Sample records for unusual ct findings

  1. Sclerosing cholangitis: CT findings.

    PubMed

    Teefey, S A; Baron, R L; Rohrmann, C A; Shuman, W P; Freeny, P C

    1988-12-01

    The value of computed tomography (CT) in the detection of primary sclerosing cholangitis (PSC) in the intrahepatic and extrahepatic biliary systems was assessed by comparing CT scans of 20 cases of PSC with cholangiographic findings. In 16 of 19 cases of extrahepatic duct disease demonstrated with cholangiography, CT demonstrated abnormalities of the common hepatic duct, or bile duct, including duct stenosis, mural nodularity, duct dilatation, wall thickening, and mural enhancement. CT demonstrated intrahepatic disease in all 20 cases, including duct dilatation, duct stenosis, pruning, and beading. CT was superior to cholangiography in characterization of the status of the intrahepatic duct system in 11 of 20 cases. In addition, CT demonstrated extrabiliary complications of PSC in 12 cases and superimposed cholangiocarcinoma in three cases. While cholangiography remains the standard for diagnosis and follow-up of PSC, CT can provide valuable information about the extent and complications of the disease. PMID:3055028

  2. Unusual thoracic CT manifestations of osteosarcoma: review of 16 cases

    Microsoft Academic Search

    Ruchi Rastogi; Rachana Garg; Sanjay Thulkar; Sameer Bakhshi; Ajay Gupta

    2008-01-01

    Pulmonary metastases are common in osteosarcoma and the most common appearance is of multiple well-defined nodules in the\\u000a lung parenchyma. However, a variety of atypical locations and presentations of osteosarcoma metastasis can occur in the thorax.\\u000a We present a review of the thoracic CT findings in 16 patients with histopathologically confirmed osteosarcoma with unusual\\u000a thoracic manifestations. The 16 patients were

  3. CT Features of an unusual calcified schwannoma of the superior laryngeal nerve.

    PubMed

    Moroni, A-L; Righini, C; Faure, C; Serra-Tosio, G; Lefournier, V

    2007-05-01

    We report the CT findings in a patient with a lateral neck mass histologically diagnosed as a laryngeal schwannoma but presenting some uncommon CT features. CT showed unusual calcified components, very rarely observed and potentially misleading for diagnosis. However, this imaging feature can be found in ancient schwannomas. Our case is, therefore, a very rare one and reviews the main differential diagnoses. PMID:17494683

  4. Atypical CT Findings in Plexiform Ameloblastoma.

    PubMed

    Arora, Karandeep Singh; Binjoo, Nagesh; Modgil, Richa; Negi, Lalit Singh; Kaur, Prabhpreet

    2014-01-01

    Ameloblastoma is an uncommon epithelial odontogenic neoplasm that is nonmineralized, locally aggressive, and, in most cases, benign. Most ameloblastomas develop in the molar-ramus region of the mandible with 70% of them arising in the molar-ramus area. Radiologically they are unilocular or multilocular radiolucency with a honeycomb or soap bubble appearance. The radiographic appearance of ameloblastoma can vary according to the type of tumor. CT is usually helpful in determining the contours of the lesion, its contents, and its extension into soft and hard tissues. Through this case we would bring to light some of the unusual CT findings which include the destruction of the surrounding structures by the lesion which appeared to be normal routine lesion when viewed clinically. PMID:25506456

  5. Atypical CT Findings in Plexiform Ameloblastoma

    PubMed Central

    Binjoo, Nagesh; Modgil, Richa; Negi, Lalit Singh; Kaur, Prabhpreet

    2014-01-01

    Ameloblastoma is an uncommon epithelial odontogenic neoplasm that is nonmineralized, locally aggressive, and, in most cases, benign. Most ameloblastomas develop in the molar-ramus region of the mandible with 70% of them arising in the molar-ramus area. Radiologically they are unilocular or multilocular radiolucency with a honeycomb or soap bubble appearance. The radiographic appearance of ameloblastoma can vary according to the type of tumor. CT is usually helpful in determining the contours of the lesion, its contents, and its extension into soft and hard tissues. Through this case we would bring to light some of the unusual CT findings which include the destruction of the surrounding structures by the lesion which appeared to be normal routine lesion when viewed clinically. PMID:25506456

  6. Primary hepatic sarcomas: CT findings

    Microsoft Academic Search

    Ri-Sheng Yu; Ying Chen; Biao Jiang; Liu-Hong Wang; Xiu-Fang Xu

    2008-01-01

    Primary hepatic sarcomas are rare tumors that are difficult to diagnose clinically. Different primary hepatic sarcomas may\\u000a have different clinical, morphologic, and radiological features. In this pictorial review, we summarized computed tomography\\u000a (CT) findings of some relatively common types of hepatic sarcomas, including angiosarcoma, epithelioid hemangioendothelioma\\u000a (EHE), liposarcoma, undifferentiated embryonal sarcoma (UES), leiomyosarcoma, malignant fibrous histiocytoma (MFH), and carcinosarcoma\\u000a (including

  7. Adrenal cortex dysfunction: CT findings

    SciTech Connect

    Huebener, K.H.; Treugut, H.

    1984-01-01

    The computed tomographic appearance of the adrenal gland was studied in 302 patients with possible endocrinologic disease and 107 patients undergoing CT for nonendocrinologic reasons. Measurements of adrenal size were also made in 100 adults with no known adrenal pathology. CT proved to be a sensitive diagnostic tool in combination with clinical studies. When blood hormone levels are increased, CT can differentiate among homogeneous organic hyperplasia, nodular hyperplasia, benign adenoma, and malignant cortical adenoma. When blood hormone levels are decreased, CT can demonstrate hypoplasia or metastatic tumorous destruction. Calcifications can be demonstrated earlier than on plain radiographs. When hormone elimination is increased, the morphologic substrate can be identified; tumorous changes can be localized and infiltration of surrounding organs recognized.

  8. Invasive gastric mucormycosis: CT findings.

    PubMed

    Samet, Jonathan D; Horton, Karen M; Fishman, Elliot K

    2008-09-01

    Mucormycosis is an uncommon fungal infection primarily seen in immunocompromised patients. We present a patient whose hospital course was rapidly complicated by invasive mucormycosis, which caused his death. Computed tomography (CT) was very helpful in characterizing the extent of involvement and directing clinical management. PMID:18071767

  9. Cyclopia and exadactyly: CT and MRI findings.

    PubMed

    Karantanas, A H; Papanikolaou, N; Danos, A; Antonakopoulos, G

    1999-11-01

    Cyclopia is a congenital abnormality consisting of fused orbits and a single eye and is the most extreme form of alobar holoprosencephaly. The present case describes the CT and MRI findings in the skull of a 33-week-old cadaver with alobar holoprosencephaly and exadactyly. PMID:10578193

  10. Reossification in Gorham's disease of the hand and wrist with unusual CT and MR imaging features.

    PubMed

    Shi, Jing; Zhang, Zekun; Li, Yuqing; Latif, Mahrukh; Gao, Feng

    2015-07-01

    Gorham's disease (GD) rarely occurs in the hand and wrist. Only nine cases of GD in the hand and wrist have been reported in the literature. The imaging technique used in all nine cases was mainly radiography. The natural history of GD is unpredictable. Spontaneous regression has been reported in a few cases. There is no consensus about the most efficient treatment of GD. Surgical resection and reconstruction with bone grafts and/or prostheses are used sparingly as bone grafts tend to be resorbed in most cases. We report a case of GD that involved the right hand and wrist in a 26-year-old male. The lesion displayed multiple areas of osteolysis in the metacarpals, carpals and proximal phalanx of the base of the thumb on radiography, while on CT and MRI, the osteolytic areas showed homogeneous density and signal intensity, similar to that of fluid. The patient was successfully treated by surgical reconstruction with autogenous iliac bone grafts. Gradual reossification in the osteolytic areas had occurred by the 3-year follow-up evaluation. This case merits special attention because of the unusual location of the involvement, unusual CT and MR imaging findings and unusual reossification in the osteolytic areas. PMID:25712769

  11. Peliosis hepatis: triphasic helical CT and dynamic MRI findings

    Microsoft Academic Search

    H. Gouya; O. Vignaux; P. Legmann; G. de Pigneux; A. Bonnin

    2001-01-01

    We report the triphasic helical computed tomographic (CT) and dynamic magnetic resonance imaging (MRI) findings in a unique case of biopsy-proven peliosis of the liver. Several reports have described the CT and MRI findings of this entity without specific appearance. This report discusses the usefulness of dynamic helical CT and MRI for the early diagnosis of peliosis.

  12. A case of secondary erythromelalgia with unusual histological findings.

    PubMed

    Bakkour, Waseem; Motta, Luisa; Stewart, Elizabeth

    2013-06-01

    Erythromelalgia clinically presents with episodic burning, erythema, and warmth of acral sites. It can be divided into primary and secondary associated with myeloproliferative and autoimmune conditions. Histology commonly shows capillary proliferation, swelling of endothelial cells, perivascular edema, and chronic inflammation with sparse lymphocytic infiltrate. We report a case of a 55-year-old man with classical secondary erythromelalgia clinically; however, he had unusual histological findings on biopsy comprising of acute perivascular infiltrate and perivascular mucin. This is the first report of such findings in the context of secondary erythromelalgia. PMID:23334520

  13. Unusual thoracic radiographic findings in children treated for Hodgkin's disease

    SciTech Connect

    Jochelson, M.S.; Tarbell, N.J.; Weinstein, H.J.

    1986-06-01

    Mantle irradiation is often part of the treatment for Hodgkin's disease. Localized pneumonitis and fibrosis are well-known sequelae of this treatment. We report nine patients with unusual thoracic radiographic findings following treatment for Hodgkin's disease. All nine had mediastinal widening. Seven of these patients received combined modality therapy in which prednisone was given with their MOPP. In these seven patients, an increase in mediastinal width developed at the same time as the radiographic changes of radiation pneumonitis. Two patients developed bilateral infiltrates extending beyond the field of radiation to the lung periphery. In one of these patients, a spontaneous pneumomediastinum developed. One patient underwent mediastinal biopsy that revealed inflammatory changes similar to those seen in radiation pneumonitis. All patients either responded to steroids or had spontaneous regression of radiographic abnormalities supporting the presumed diagnosis of treatment related changes. Recognition of these unusual sequelae of mantle irradiation will aid in differentiating them from infection or tumor and lead to prompt, appropriate treatment.

  14. CT findings in nonmucosal eosinophilic gastroenteritis.

    PubMed

    Van Hoe, L; Vanghillewe, K; Baert, A L; Ponette, E; Geboes, K; Stevens, E

    1994-01-01

    A 22-year-old patient with eosinophilic gastroenteritis with predominantly submucosal and muscular involvement is presented. The benefits of CT, using water as an orally administered contrast agent, are stressed, because CT enabled the authors to suggest a full thickness biopsy, after mucosal biopsies had remained repeatedly negative. PMID:8089335

  15. CT findings of phytobezoar associated with small bowel obstruction

    Microsoft Academic Search

    Ji-Hoon Kim; Hyun Kwon Ha; Min Sohn; Ah Kim; Tae Kim; Pyo Kim; Moon-Gyu Lee; Seung-Jae Myung; Suk-Kyun Yang; Hwoon-Yong Jung; Jin Kim

    2003-01-01

    .   The purpose of this study was to evaluate CT findings of phytobezoar associated with small bowel obstruction. We evaluated\\u000a abdominal CT of 19 patients with phytobezoar. Abdominal CT of 6 patients with small bowel feces was included for the comparison.\\u000a On CT we analyzed morphological features of phytobezoars such as location, number, size, shape, and the presence or absence

  16. Gastric involvement in Waldenstrom macroglobulinemia: CT findings

    Microsoft Academic Search

    H. M. Qutub; A. C. Wilbur; S. Dada

    1997-01-01

    .   Waldenstrom macroglobulinemia is a plasma cell dyscrasia that rarely presents with gastrointestinal involvement. We report\\u000a a case of gastric involvement of Waldenstrom macroglobulinemia detected by CT.

  17. CT findings in silicosis due to denim sandblasting

    Microsoft Academic Search

    Fatih Alper; Metin Akgun; Omer Onbas; Omer Araz

    2008-01-01

    The purpose of this study was to describe the findings of CT performed on denim sandblasters with silicosis. Fifty consecutive\\u000a male patients with silicosis were evaluated. Their clinical data and pulmonary function tests (PFT) were obtained. The CT\\u000a findings were recorded and the correlations between CT nodular profusion score and the other parameters were assessed. The\\u000a diagnoses of the patients

  18. Mesenteric panniculitis in oncologic patients: PET-CT findings

    Microsoft Academic Search

    R Zissin; U METSER; D HAIN; E EVEN-SAPIR

    2006-01-01

    The aim of this study is to assess the role of PET\\/CT in differentiating between mesenteric panniculitis (MP) and co-existing MP and mesenteric tumoural involvement. A total of 33 PET\\/CT examinations, of 19 oncologic patients (16 men and three women with ages ranging from 48 years to 83 years) with findings of MP on the CT part of the study

  19. Cystic lymphangioma of the pancreas: CT and pathologic findings

    Microsoft Academic Search

    G. Gray; K. Fried; J. Iraci

    1998-01-01

    .   A case of pancreatic cystic lymphangioma is presented with CT and pathologic findings. CT demonstrated a large septated cystic\\u000a mass in the left abdomen in an otherwise healthy young female. A diagnosis of lymphangioma was made after excision and pathologic\\u000a examination.

  20. Abdominal visceral calcification in primary amyloidosis: CT findings

    Microsoft Academic Search

    J. E. Jacobs; B. A. Birnbaum; E. E. Furth

    1997-01-01

    .   The computed tomographic (CT) findings of extensive visceral calcification involving both the liver and spleen in a patient\\u000a with primary amyloidosis are presented. Although the CT imaging appearances of amyloidosis are often nonspecific, visceral\\u000a calcification represents an important diagnostic clue for differentiating this entity from other infiltrative parenchymal\\u000a diseases.

  1. Abdominal visceral calcification in primary amyloidosis: CT findings.

    PubMed

    Jacobs, J E; Birnbaum, B A; Furth, E E

    1997-01-01

    The computed tomographic (CT) findings of extensive visceral calcification involving both the liver and spleen in a patient with primary amyloidosis are presented. Although the CT imaging appearances of amyloidosis are often nonspecific, visceral calcification represents an important diagnostic clue for differentiating this entity from other infiltrative parenchymal diseases. PMID:9233892

  2. PET/CT findings in acute gastric anisakiasis.

    PubMed

    Abe, Koichiro; Yoshikai, Tomonori; Baba, Shingo; Isoda, Takuro; Honda, Hiroshi

    2014-06-01

    Acute gastric anisakiasis is caused by the consumption of raw or undercooked fish containing Anisakis larvae. Although several reports have demonstrated the CT features of acute gastric anisakiasis, little is known about the FDG PET/CT findings. We report a 59-year-old woman who underwent FDG PET/CT and was finally diagnosed as having acute gastric anisakiasis. The PET/CT demonstrated focal FDG accumulation in the fornix of the gastric wall and lymph nodes in the lesser curvature and paraaortic regions. PMID:24810783

  3. Pediatric Burkitt’s lymphoma: CT findings

    Microsoft Academic Search

    Atheel A. Kamona; Maan A. El-Khatib; Maisa Y. Swaidan; Mohamed S. Jarar; Abdallah J. Suleiman; Hani M. Al Ali; Ahmed B. Basharaheel; Asem H. Mansour

    2007-01-01

    Purpose  To review and analyze all CT scans of the cases of Burkitt’s lymphoma (BL) in children diagnosed in our institution.\\u000a \\u000a \\u000a \\u000a Materials and methods  A retrospective analysis of 33 children with BL between the years 2003 and 2005 seen in our institution was undertaken. Twenty-nine\\u000a male and four female patients from age 3 to 16 years (with a mean age 5.9 years) were reviewed.

  4. “Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

    PubMed Central

    Oza, Vikash; Frieden, Ilona J.; Cordoro, Kelly M.; Yagi, Shigeo; Howard, Renee; Kristal, Leonard; Ginocchio, Christine C.; Schaffer, Julie; Maguiness, Sheilagh; Bayliss, Susan; Lara-Corrales, Irene; Garcia-Romero, Maria Teresa; Kelly, Dan; Salas, Maria; Oberste, M. Steven; Nix, W. Allan; Glaser, Carol; Antaya, Richard

    2013-01-01

    OBJECTIVE: To characterize the atypical cutaneous presentations in the coxsackievirus A6 (CVA6)–associated North American enterovirus outbreak of 2011–2012. METHODS: We performed a retrospective case series of pediatric patients who presented with atypical cases of hand, foot, and mouth disease (HFMD) from July 2011 to June 2012 at 7 academic pediatric dermatology centers. Patients were included if they tested positive for CVA6 or if they met clinical criteria for atypical HFMD (an enanthem or exanthem characteristic of HFMD with unusual morphology or extent of cutaneous findings). We collected demographic, epidemiologic, and clinical data including history of skin conditions, morphology and extent of exanthem, systemic symptoms, and diagnostic test results. RESULTS: Eighty patients were included in this study (median age 1.5 years, range 4 months–16 years). Seventeen patients were CVA6-positive, and 63 met clinical inclusion criteria. Ninety-nine percent of patients exhibited a vesiculobullous and erosive eruption; 61% of patients had rash involving >10% body surface area. The exanthem had a perioral, extremity, and truncal distribution in addition to involving classic HFMD areas such as palms, soles, and buttocks. In 55% of patients, the eruption was accentuated in areas of eczematous dermatitis, termed “eczema coxsackium.” Other morphologies included Gianotti-Crosti–like (37%), petechial/purpuric (17%) eruptions, and delayed onychomadesis and palm and sole desquamation. There were no patients with serious systemic complications. CONCLUSIONS: The CVA6-associated enterovirus outbreak was responsible for an exanthem potentially more widespread, severe, and varied than classic HFMD that could be confused with bullous impetigo, eczema herpeticum, vasculitis, and primary immunobullous disease. PMID:23776120

  5. CT findings in ulcerative, granulomatous, and indeterminate colitis

    SciTech Connect

    Gore, R.M.; Marn, C.S.; Kirby, D.F.; Vogelzang, R.L.; Neiman, H.L.

    1984-08-01

    Eight patients with ulcerative colitis, three with colitis indeterminate, and 15 patients with Crohn disease were studied by computed tomography (CT) to establish CT criteria for each disorder in hopes of providing a new diagnostic perspective useful in the radiographic evaluation of inflammatory colitis. The CT findings in ulcerative colitis included thickening of the colon wall, which was characterized by inhomogeneous attenuation and a target appearance of the rectum, and proliferation of perirectal fat. Bowel wall thickening with homogeneous attenuation, fistula and abscess formation, and mesenteric abnormalities were observed in patients with Crohn colitis. Patients with colitis indeterminate showed colonic changes on CT observed in both disorders. Initial experience suggests that CT can differentiate patients with well established ulcerative and Crohn colitis.

  6. CT findings in silicosis due to denim sandblasting.

    PubMed

    Alper, Fatih; Akgun, Metin; Onbas, Omer; Araz, Omer

    2008-12-01

    The purpose of this study was to describe the findings of CT performed on denim sandblasters with silicosis. Fifty consecutive male patients with silicosis were evaluated. Their clinical data and pulmonary function tests (PFT) were obtained. The CT findings were recorded and the correlations between CT nodular profusion score and the other parameters were assessed. The diagnoses of the patients were classified as accelerated silicosis (n = 43) and acute silicosis (n = 7). The most common CT finding was centrilobular nodules. Twenty-three patients had complicated silicosis based on pleural involvement and presence of progressive massive fibrosis (PMF). Lymphadenopathy (LAP) was positive in 50% of the patients, with calcification in 24%. The CT grade was highly correlated with the clinical data such as exposure duration and PFT. Our findings suggest that the clinical manifestation of silicosis in denim sandblasters is severe. Although the duration of exposure is shorter the rate of complicated silicosis patients with pleural involvement was unexpectedly higher in the cases. Because the most common radiological appearance was nodules and the CT grading of the nodules was highly correlated with the clinical data, nodule grading may be used in the management of such cases. PMID:18581116

  7. Scrub typhus associated hepatic dysfunction and abdominal CT findings

    PubMed Central

    Park, Man Je; Lee, Hyoun Soo; Shim, Sang Goon; Kim, So Hee

    2015-01-01

    Objective: This retrospective study investigated abnormal hepatic dysfunction and abdominal computed tomography (CT) findings in scrub typhus. Methods: Three hundred forty nine adult patients were diagnosed with scrub typhus. Ninety four underwent abdominal CT. The CT images were reviewed by the attending radiologist. Patient data of history, symptoms, signs, and results of laboratory tests were collected from the electronic medical records. Results: In 349 patients with scrub typhus, elevation of aspartate aminotransferase (78.5%) and alanine aminotransferase (63.0%) were dominant compared to alkaline phosphatase (27.2%) and total bilirubin (16.1%). Abdominal CT findings of 94 patients were, in descending order of frequency, enlarged lymph node (53.2%), inhomogeneous enhancement of liver (47.9%), splenomegaly (46.8%), ascites (28.7%), low attenuation of periportal areas (27.7%), gallbladder wall thickening (17.0%), and splenic infarct (6.4%). Also, the level of aspartate aminotransferase tended to be elevated according to the number of CT findings (P= 0.028) Conclusions: We found that abdominal CT manifestations of scrub typhus with elevated aminotransferases were varied and not specific. However, knowledge of these findings may evoke the recognition of scrub typhus by clinicians in endemic areas. PMID:26101478

  8. Uncommon CT Findings in Relapsing Polychondritis

    Microsoft Academic Search

    Laura E. Faix; Barton F. Branstetter

    Summary: Relapsing polychondritis is a rare inflammatory disorder of cartilage with well-established clinical features and imaging characteristics. Abnormal calcification and erosion of cartilaginous structures are the traditional ra- diographic findings. As with any disease, aberrancies of the expected clinical presentation may lead to a delayed (or missed) diagnosis. We discuss a rare case of relapsing polychondritis in which the diagnosis

  9. Serial CT Findings of Paragonimus Infested Dogs and the Micro-CT Findings of the Worm Cysts

    PubMed Central

    Lee, Chang Hyun; Goo, Jin Mo; Lee, Hyun Ju; Hong, Sung-Tae; Shen, Cheng Hua; Chung, Doo Hyun; Son, Kyu Ri; Chang, Jung Min; Eo, Hong

    2007-01-01

    Objective To investigate the serial CT findings of Paragonimus westermani infected dogs and the microscopic structures of the worm cysts using Micro-CT. Materials and Methods This study was approved by the committee on animal research at our institution. Fifteen dogs infected with P. westermani underwent serial contrast-enhanced CT scans at pre-infection, after 10 days of infection, and monthly thereafter until six months for determining the radiologic-pathologic correlation. Three dogs (one dog each time) were sacrificed at 1, 3 and 6 months, respectively. After fixation of the lungs, both multi-detector CT and Micro-CT were performed for examining the worm cysts. Results The initial findings were pleural effusion and/or subpleural ground-glass opacities or linear opacities at day 10. At day 30, subpleural and peribronchial nodules appeared with hydropneumothorax and abdominal or chest wall air bubbles. Cavitary change and bronchial dilatation began to be seen on CT scan at day 30 and this was mostly seen together with mediastinal lymphadenopathy at day 60. Thereafter, subpleural ground-glass opacities and nodules with or without cavitary changes were persistently observed until day 180. After cavitary change of the nodules, the migratory features of the subpleural or peribronchial nodules were seen on all the serial CT scans. Micro-CT showed that the cyst wall contained dilated interconnected tubular structures, which had communications with the cavity and the adjacent distal bronchus. Conclusion The CT findings of paragonimiasis depend on the migratory stage of the worms. The worm cyst can have numerous interconnected tubular channels within its own wall and these channels have connections with the cavity and the adjacent distal bronchus. PMID:17923779

  10. Cystic angiomatosis with splenic involvement: unusual MRI findings

    Microsoft Academic Search

    F. M. Vanhoenacker; A. M. De Schepper; H. De Raeve; Z. Berneman

    2003-01-01

    Cystic angiomatosis is a rare disorder with a poor prognosis. We describe a case of a 33-year-old woman who presented with longstanding bone pain, hemolytic anemia, and an enlarged spleen. Radiologically, multiple osseous lesions with a mixed pattern of lytic and sclerotic areas were seen within the shoulders, spine, and pelvis. On CT and MRI of the abdomen, the spleen

  11. Unusual histological findings in a child with idiopathic nephrotic syndrome

    Microsoft Academic Search

    James Springate; Tibor Nadasdy

    2007-01-01

    We report a 2-year-old child with corticosteroid-resistant nephrotic syndrome whose renal biopsy revealed light microscopically\\u000a normal glomeruli but highly unusual finger-like projections and arches of the glomerular basement membrane. To our knowledge,\\u000a the association between nephrotic syndrome and this patient’s rare ultrastuctural lesion has not been previously documented\\u000a in the literature. It is not certain whether this basement membrane is

  12. Trisomy 2p: Analysis of unusual phenotypic findings

    Microsoft Academic Search

    Iosif W. Lurie; Helena G. Ilyina; Dora B. Gurevich; Natalja V. Rumyantseva; Irena V. Naumchik; Claudio Castellan; Adelheid Hoeller; Albert Schinzel

    1995-01-01

    We present three probands with partial trisomies 2p21-23 due to ins(4;2)(q21;p21p23) pat, 2p23-pter due to t(2;4)(p23;q35)mat, and 2p21-pter due to t(2;11)(p21;q23.3)mat. More than 50 cases of partial trisomy 2p have been reviewed and some abnormalities, unusual for most other types of structural autosomal imbalance, have been found in patients with inherited forms of 2p trisomy and in their non-karyotyped sibs.

  13. Methanol poisoning: acute MR and CT findings in nine patients

    Microsoft Academic Search

    S. Sefidbakht; A. R. Rasekhi; K. Kamali; A. Borhani Haghighi; A. Salooti; A. Meshksar; H. R. Abbasi; M. Moghadami; S. A. Nabavizadeh

    2007-01-01

    Introduction  Methanol poisoning is an uncommon but potent central nervous system toxin. We describe here the CT and MR findings in nine\\u000a patients following an outbreak of methanol poisoning.\\u000a \\u000a \\u000a \\u000a Methods  Five patients with a typical clinical presentation and elevated anion and osmolar gaps underwent conventional brain MRI with\\u000a a 1.5-T Gyroscan Interna scanner. In addition nonenhanced CT was performed in another three

  14. Unusual lymph node metastases of prostate cancer detected by 18F-fluorocholine PET/CT.

    PubMed

    Pinaquy, J B; Allard, J B; Cornelis, F; Pasticier, G; De Clermont, H

    2015-04-01

    A 65-year-old patient with prostate adenocarcinoma was explored by 18F-fluorocholine (FCH) PET/CT for pretreatment staging because of a high risk of prostate cancer. Images showed multiple foci with increased uptake of 18F-FCH within some pelvic and retroperitoneal lymph nodes, osseous foci (iliac bones and sacrum), and much more unusual, increased uptake foci within some left supraclavicular and left axillary lymph nodes. Owing to the rarity of spread to supraclavicular lymph nodes, surgical removal was performed and revealed prostate cancer metastases. PMID:25674860

  15. A Case of Severe Sepsis Presenting Marked Decrease of Neutrophils and Interesting Findings on Dynamic CT

    PubMed Central

    Makino, Isamu; Tajima, Hidehiro; Kitagawa, Hirohisa; Nakagawara, Hisatoshi; Miyashita, Tomoharu; Nakanuma, Shinichi; Hayashi, Hironori; Takamura, Hiroyuki; Fushida, Sachio; Ohta, Tetsuo

    2015-01-01

    Patient: Male, 60 Final Diagnosis: Sepsis Symptoms: Fever • shock Medication: Sivelestat sodium hydrate Clinical Procedure: PMX-DHP • CHDF Specialty: Infectious Diseases Objective: Unusual clinical course Background: In a patient with severe sepsis, we sometimes observe immediate decrease of the counts of white blood cells (WBCs) and neutrophils, which is known as an indicator for poor prognosis. We observed marked decrease of white blood cells and neutrophils on blood examination and interesting findings on dynamic CT. Here, we present the case of a patient with severe postoperative sepsis occurring after major abdominal surgery and we discuss the mechanism of such clinical presentations. Case Report: A 60-year-old man received pancreatoduodenectomy with colectomy for pancreatic cancer. He developed a high fever on postoperative day 3. We observed marked decrease of WBCs and neutrophils on blood examination. We also observed slight swelling of the liver, inhomogeneous enhancement of liver parenchyma in arterial phase, and periportal low density in the Glisson capsule in portal phase, without any findings indicating infectious complications on dynamic CT. WBCs and neutrophils increased above normal range in just 6 hours. Blood culture examination performed while the patient had a high fever was positive for Aeromonas hydrophila. After receiving intensive care, he promptly recovered from severe sepsis. The CT findings disappeared on second dynamic CT examination performed 3 days after the first examination. Conclusions: We treated a patient with severe sepsis after major abdominal surgery who presented very rapid change of the counts of WBCs and neutrophils and interesting CT findings in the liver. We rescued him from a critical situation by prompt and intensive treatment. Research is needed to accumulate and analyze data from more patients who present a similar clinical course to better understand their pathophysiological conditions. PMID:26020838

  16. Traumatic optic neuropathy: facial CT findings affecting visual acuity.

    PubMed

    Reddy, Ramachandra P; Bodanapally, Uttam K; Shanmuganathan, Kathirkamanathan; Van der Byl, Giulia; Dreizin, David; Katzman, Lee; Shin, Robert Kang

    2015-08-01

    The purpose of this study was to determine the relationship between admission visual acuity (VA) and facial computed tomographic (CT) findings of traumatic optic neuropathy (TON). We retrospectively evaluated CT findings in 44 patients with TON. Mid-facial fractures, extraconal and intraconal hematomas, hematomas along the optic nerve and the posterior globe, optic canal fracture, nerve impingement by optic canal fracture fragment, and extraconal and intraconal emphysema were evaluated. CT variables of patients with and without available VA were compared. VA was converted into logarithm of the minimum angle of resolution (logMAR) to provide a numeric scale for the purpose of statistical analysis. The risk factors related to poor VA on univariate analysis were as follows: intraconal hematoma [median logMAR -4.7 versus -1.15, p?=?0.016] and hematoma along the optic nerve [median -4.7 versus -1.3, p?=?0.029]. Intraconal hematoma was the best predictor of poor VA (coefficient, 1.01; SE, 0.34; and p?=?0.008). Receiver operating characteristic (ROC) curve analysis showed that the presence of intraconal hematoma and hematoma along the optic nerve predicted poor VA (logMAR of -3.7 or lower) with an area under the curve of 0.8 and 0.85, respectively. TON patients at higher risk of severe visual impairment may be identified based on admission facial CT. PMID:25563705

  17. Mesenteric cystic lymphangioma with myxoid degeneration: Unusual CT and MR manifestations

    Microsoft Academic Search

    S.-F. Ko; S.-H. Ng; C.-S. Shieh; J.-W. Lin; C.-C. Huang; T.-Y. Lee

    1995-01-01

    We report an unusual case of mesenteric cystic lymphangioma presenting as a large multilocular mass with a well-enhanced solid component and a central cleft, which were were pathologically correlated to the prominent stromal myxoid degeneration interspersed with abundant capillaries and the central fibrosis, respectively. The findings of computed tomography and magnetic resonance imaging are illustrated. Recognition of the multilocular configuration

  18. Trisomy 2p: Analysis of unusual phenotypic findings

    SciTech Connect

    Lurie, I.W.; Ilyina, H.G.; Gurevich, D.B. [Belorussian Research Institute of Hereditary Disease, Minsk (Russian Federation)] [and others

    1995-01-16

    We present three probands with partial trisomies 2p21-23 due to ins(4;2)(q21;p21p23) pat, 2p23-pter due to t(2;4)(p23;q35)mat, and 2p21-pter due to t(2;11)(p21;q23.3)mat. More than 50 cases of partial trisomy 2p have been reviewed and some abnormalities, unusual for most other types of structural autosomal imbalance, have been found in patients with inherited forms of 2p trisomy and in their non-karyotyped sibs. Neural tube defects (anencephaly, occipital encephalocele, and spina bifida) were found in five probands and 4/6 affected non-karyotyped sibs. The only triplicated segment common to all was 2p24. Different forms of {open_quotes}broncho-pulmonary a/hypoplasia{close_quotes} (including two cases of lung agenesis) were described in four patients (overlapping triplicated segment was 2p21-p25). Three patients (with overlapping triplicated segment 2p23-p25) had diaphragmatic hernia. Abnormal rotation of the heart or L-transposition of large vessels (with or without visceral heterotaxia) was found in two infants (overlapping triplicated segment 2p23-p24). In two patients with common triplicated segment 2p22.3-p25, neuroblastoma has been described. The occurrence of all these defects may be explained either by the action of the same gene(s) mapped to 2p24 or by action of some independent factors located in different segments of the short arm. Although the latter hypothesis is much less probable, it can not be rejected at the present time. We propose the existence of a genetic system controlling surveillance of an abnormal embryo to explain the phenotypic differences between patients with the same imbalance within a family. In some {open_quotes}restrictive{close_quotes} combinations the abnormal embryos will die, although in {open_quotes}permissive{close_quotes} combinations they can survive. 47 refs., 2 figs., 3 tabs.

  19. Horizontal gaze palsy with progressive scoliosis: CT and MR findings.

    PubMed

    Bomfim, Rodrigo C; Távora, Daniel G F; Nakayama, Mauro; Gama, Rômulo L

    2009-02-01

    Horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare congenital disorder characterized by absence of conjugate horizontal eye movements and progressive scoliosis developing in childhood and adolescence. We present a child with clinical and neuroimaging findings typical of HGPPS. CT and MRI of the brain demonstrated pons hypoplasia, absence of the facial colliculi, butterfly configuration of the medulla and a deep midline pontine cleft. We briefly discuss the imaging aspects of this rare entity in light of the current literature. PMID:19020872

  20. Brain CT-Scan Findings in Unconscious Patients after Poisoning.

    PubMed

    Taheri, Morteza Sanei; Noori, Maryam; Shakiba, Majid; Jalali, Amir Hossein

    2011-03-01

    The aim of this study was to identify and describe brain CT findings in patients with poisoning or drug overdose and altered mental status. In this study, 403 patients with some degree of loss of consciousness who referred due to poisoning or drug overdose were evaluated by brain CT. The most common cause of intoxication was suicide. Intoxication status was determined by the physician and was mainly based on a history of intoxication, positive toxicologic screen result, or physical evidence suggesting intoxication. Among 403 unconscious patients, 229 patients who were ingested or inhaled Benzodiazepine, Carbamazepine, Carbon Monoxide, Ethanol, Methanol, Opium, Tricyclic antidepressants, and Tramadol included in the study. Others had used multiple drugs and/or toxins, or their intoxication was unknown. Mean age of patients was 37.6 ± 17.7 years (14-95). Among them, 181 (79%) were male. Among all patients, 92 had consumed opium (40.2%), 47 had consumed Benzodiazepines (20.5%) and other patients had been overdosed by other drugs or exposed to other poisonous agents. Totally 38 (16.5%) patients had abnormal CT findings. These included 10 cases of infarction, four cases of hemorrhage, two cases of herniation, 13 cases of edema, and 10 cases of basal ganglia changes (including 9 cases of hypodensity and one case of hypodensity with hemorrhage). A good knowledge of the CT findings in unconscious patients due to poisoning or drug overdose seems to be necessary for radiologists and clinicians. This study is unique in that it reported most of the radiological findings in these patients. PMID:23675213

  1. Renal infarction: CT diagnosis and correlation between CT findings and etiologies

    SciTech Connect

    Wong, W.S.; Moss, A.A.; Federle, M.P.; Cochran, S.T.; London, S.S.

    1984-01-01

    The CT scans and the clinical records of 12 patients who had renal infarction were reviewed. The renal infarcts were classified as either focal or global. The CT findings were correlated with the etiologies of renal infarction. Embolism was the most common cause of renal infarcts that were multifocal with involvement of both kidneys. Trauma caused a unilateral global type of infract. A case of sickle cell anemia presented with multiple ''slit-like'' focal infarcts and enlarged kidneys. Forty-seven per cent of infarcts demonstrated the cortical rim sign, 11% were acapsular fluid collection, and 6% had an abnormally thickened renal fascia.

  2. Unusual histopathological findings in appendectomy specimens: A retrospective analysis and literature review

    PubMed Central

    Akbulut, Sami; Tas, Mahmut; Sogutcu, Nilgun; Arikanoglu, Zulfu; Basbug, Murat; Ulku, Abdullah; Semur, Heybet; Yagmur, Yusuf

    2011-01-01

    AIM: To document unusual findings in appendectomy specimens. METHODS: The clinicopathological data of 5262 patients who underwent appendectomies for presumed acute appendicitis from January 2006 to October 2010 were reviewed retrospectively. Appendectomies performed as incidental procedures during some other operation were excluded. We focused on 54 patients who had unusual findings in their appendectomy specimens. We conducted a literature review via the PubMed and Google Scholar databases of English language studies published between 2000 and 2010 on unusual findings in appendectomy specimens. RESULTS: Unusual findings were determined in 54 (1%) cases by histopathology. Thirty were male and 24 were female with ages ranging from 15 to 84 years (median, 32.2 ± 15.1 years). Final pathology revealed 37 cases of enterobiasis, five cases of carcinoids, four mucinous cystadenomas, two eosinophilic infiltrations, two mucoceles, two tuberculosis, one goblet-cell carcinoid, and one neurogenic hyperplasia. While 52 patients underwent a standard appendectomy, two patients who were diagnosed with tuberculous appendicitis underwent a right hemicolectomy. All tumors were located at the distal part of the appendix with a mean diameter of 6.8 mm (range, 4-10 mm). All patients with tumors were alive and disease-free during a mean follow-up of 17.8 mo. A review of 1366 cases reported in the English literature is also discussed. CONCLUSION: Although unusual pathological findings are seldom seen during an appendectomy, all appendectomy specimens should be sent for routine histopathological examination. PMID:21528073

  3. [Unusual findings in a death caused by a car fire].

    PubMed

    Bohnert, Michael; Schmidt, Ulrike; Werp, Jürgen; Simon, Karl-Heinz

    2007-01-01

    Witnesses detected a burning car in the parking lot next to a discotheque in the early morning hours. After the fire had been extinguished, the charred body of the 23-year-old car owner was found in the driver's seat. The young man had been a guest of the discotheque the previous night and consumed plenty of alcoholic drinks. The traces left by the fire on the car suggested that the fire had started in the passenger compartment. At autopsy, greyish-brown discoloration and induration of the mucosa of the respiratory tract were found in addition to massive aspiration of soot and signs of soot swallowing. The macroscopic and histological findings pointed to a chemical burn of the airways probably caused by chlorine gases developing when the covering of the passenger compartment was burning. Chemical burns due to inhalation, aspiration and swallowing of soot are all signs of vitality, so that a smoldering fire must have gone on for a while inside the car with the windows closed. The most probable cause of the fire is that clothing or textile material in the car was set on fire by a burning cigarette. PMID:17380939

  4. Indicative findings of pancreatic cancer in prediagnostic CT.

    PubMed

    Ahn, Sung Soo; Kim, Myeong-Jin; Choi, Jin-Young; Hong, Hye-Suk; Chung, Yong Eun; Lim, Joon Seok

    2009-10-01

    We examined 20 prediagnostic CTs from 16 patients for whom the diagnosis of pancreatic cancer was delayed until full diagnostic CT was performed. Three radiologists independently reviewed the prediagnostic CTs along with 50 CTs of control subjects, including patients without pancreatic disease (n = 38) or with chronic pancreatitis without calcification visible on CT (n = 12). The reviewers recorded the presence of biliary or pancreatic ductal dilation, interruption of the pancreatic duct, distal parenchymal atrophy, contour abnormality and focal hypoattenuation. Frequency, sensitivity and specificity of the significant findings were calculated. Logistic regression analysis was performed. Findings indicative of pancreatic cancer were seen on 85% (17/20) of the prediagnostic CTs. Patients with pancreatic cancer were significantly (p < 0.05) more likely to show focal hypoattenuation, pancreatic duct dilation, interruption of the pancreatic duct, and distal parenchymal atrophy, with sensitivities and specificities of 75%/84%, 50%/78%, 45%/82% and 45%/96%, respectively. Focal hypoattenuation and distal parenchymal atrophy were the independent predictors of pancreatic cancer with odds ratios of 20.92 and 11.22, respectively. In conclusion, focal hypoattenuation and pancreatic duct dilation with or without interruption, especially when accompanied by distal parenchymal atrophy, were the most useful findings for avoiding delayed diagnosis of pancreatic cancer. PMID:19415290

  5. A patient with features of albright hereditory osteodystrophy and unusual neuropsychiatric findings without coding Gsalpha mutations

    PubMed Central

    2014-01-01

    Background Pseudohypoparathyroidism(PHP) is a heterogeneous group of rare metabolic disorders characterized by hypocalcemia and hyperphosphatemia resulting from PTH resistance. Different forms of PHP have been reported based on biochemical and clinical manifestation and genetic findings. Most of these forms are caused by defects in GNAS, an imprinted gene locus with multiple subunits. We reported a 12- year- old girl with unusual clinical manifestations of Pseudopseudohypoparathyroidism(PPHP). Methods After clinical and biochemical evaluations, the patients’ genomic DNA was isolated from peripheral blood leukocytes using salting out method. The whole coding sequences of GNAS gene including 13 exons were amplified by PCR. Quantitative PCR reactions were performed too. Findings We described a 12- year- old girl with Albright Hereditory osteodystrophy (AHO) phenotype, poor school performance, some abnormal movements, TSH resistance with normal serum calcium and phosphorus levels and normal Gs? bioactivity with no mutation in GNAS exons. Unusual neuropsychiatric findings in this patient were compatible with Asperger syndrome. Conclusions According to our findings this patient could not be categorized in any of PHP subgroups. Identifying of such individuals may be useful to discover different genetic patterns in pseudohypoparathyroidism and pseudopseudohypoparathyroidism. It is important to identify patients in whom PHP is caused by novel GNAS mutations, as careful investigations of these findings will likely further our knowledge of this complex and this unique disorder. In addition this case presented with unusual neuropsychiatric findings which has not been reported up to now. PMID:24959527

  6. Wassel's Type V Polydactyly with Plain Radiographic and CT Findings

    PubMed Central

    Mete, Berna Dirim; Altay, Canan; Gursoy, Merve; Oyar, Orhan

    2015-01-01

    Duplication of the thumb is the most common polydactyly of the hand. Wassel's classification is frequently used to classify the polydactyly of the hand. His classification was based on the level of duplication and the number of bones in the thumb, and has seven groups (Types I–VII) according to the level of the bifurcation, except for his Type VII. The most common type is the bifurcation at the metacarpophalangeal joint (Type IV). In this paper, we report a very rare case of Type V thumb polydactyly in a 42-year-old man, who presented with swan neck deformity of the radial thumb and discuss the plain radiography and computed tomography (CT) findings. Kumar recently reported plain radiography findings in a case of bifid first metacarpal in a 13-year-old girl, who presented with swan neck deformity of the left thumb. To our knowledge, our case is the second presented case that has a swan neck deformity with bifid metacarpal. PMID:25861550

  7. Intra-abdominal desmoplastic small round-cell tumour: multiphase CT findings in two children

    Microsoft Academic Search

    Jin Hyoung Kim; Hyun Woo Goo; Chong Hyun Yoon

    2003-01-01

    We report the multiphase CT findings of intra-abdominal desmoplastic small round-cell tumour (DSRCT) in two children. CT showed a huge heterogeneous intraperitoneal mass with or without direct invasion into solid organs such as liver or kidney, extensive intraperitoneal seeding, intratumoural calcification, ascites, and lymphadenopathy. DSRCT should be included in the differential diagnosis of malignant intraperitoneal neoplasm in children. Multiphase CT

  8. Automatically Pairing Measured Findings across Narrative Abdomen CT Reports

    PubMed Central

    Sevenster, Merlijn; Bozeman, Jeffrey; Cowhy, Andrea; Trost, William

    2013-01-01

    Radiological measurements are one of the key variables in widely adopted guidelines (WHO, RECIST) that standardize and objectivize response assessment in oncology care. Measurements are typically described in free-text, narrative radiology reports. We present a natural language processing pipeline that extracts measurements from radiology reports and pairs them with extracted measurements from prior reports of the same clinical finding, e.g., lymph node or mass. A ground truth was created by manually pairing measurements in the abdomen CT reports of 50 patients. A Random Forest classifier trained on 15 features achieved superior results in an end-to-end evaluation of the pipeline on the extraction and pairing task: precision 0.910, recall 0.878, F-measure 0.894, AUC 0.988. Representing the narrative content in terms of UMLS concepts did not improve results. Applications of the proposed technology include data mining, advanced search and workflow support for healthcare professionals managing radiological measurements. PMID:24551406

  9. Three rounds as "tandem bullets": unusual findings in a case of a suicidal gunshot to the head.

    PubMed

    Tattoli, Lucia; Schmid, Simone; Tsokos, Michael

    2014-12-01

    We report an unusual case of suicide in which three 7.65 caliber projectiles were found in the single gunshot wound to the head of a 53-year-old man. Based on data collected at the death scene, CT scan, autopsy findings, and ballistics analysis, the events were reconstructed as follows: two 7.65 mm rounds had already been fired from the 9 mm Makarov pistol the subject was using but, being a smaller caliber, the cartridges had slipped forward and lodged within the barrel. When a third 7.65 mm cartridge was chambered and the gun fired for the third time, the nose of the last bullet hit the lodged bullets and all three rounds were propelled out of the muzzle in tandem as a single shot. Ballistic investigations confirmed that the kinetic energy of the three tandem bullets would have been sufficient to perforate the skull. In cases of gunshot wounds where the manner of death is unclear, a number of well-described circumstantial parameters, such as an atypical anatomical location of the gunshot, unusual firearm, or ammunition, as well as ambiguous autopsy findings, can raise doubts about the manner of death. In very rare cases, despite a single entrance wound, two or more bullets are recovered from the body, fired by the same weapon at the same time (the so-called "tandem bullet" phenomenon). Injuries by "tandem bullets" have crucial implications in gunshot deaths because of the mismatch between the number of entrance and exit wounds and the number of bullets found in or near the body. PMID:25091600

  10. Pulmonary Tuberculosis Confirmed by Percutaneous Transthoracic Needle Biopsy: Analysis of CT Findings and Review of Correlations with Underlying Lung Disease

    PubMed Central

    Choo, Ji Young; Lee, Ki Yeol; Kim, Mi-young; Kang, Eun-young; Oh, Yu Whan; Lee, Seung Hwa; Seo, Bo Kyung; Je, Bo Kyung

    2014-01-01

    Background: Pulmonary tuberculosis (TB) can produce unusual radiographic findings. Further, negative sputum and bronchoscopic results are common. Early diagnosis is equally as significant as treatment in the reduction of morbidity and mortality associated with pulmonary TB. Aims: The aim of this study was to assess computed tomography (CT) findings of pulmonary TB, confirmed via percutaneous transthoracic needle biopsy (PTNB), and to correlate these findings with coexisting, underlying, lung diseases if present. Study Design: Cross sectional study. Methods: We selected eighty-four patients who were diagnosed with pulmonary TB by way of PTNB. Initially, acid-fast bacilli smear test results from these patients were negative. CT findings were reviewed to detect the presence of parenchymal abnormalities as follows: nodule(s) (<3 cm in diameter), mass (any masses ?3 cm), daughter nodules, air-space consolidation, cavitation, calcification, lymphadenopathy, mediastinal lymphadenopathy, and associated lung parenchymal disease. Results: The CT findings of pulmonary TB confirmed by PTNB included nodules in 44 of 84 (52.4%) cases; 15 of these 44 cases (34.1%) had daughter nodules. The second most common finding was masses in 24 cases (28.6%), nine of which also had daughter nodules. 16 cases (19.0%) displayed nonsegmental consolidation. Of these 16 cases, four had coexisting usual interstitial pneumonia; four others had emphysema. Two patients with a mass had underlying pneumoconiosis. Conclusion: Nodules or a mass mimicking lung cancer were the most common findings on CT scans in patients with pulmonary TB, confirmed via PTNB. The second most common finding was airspace consolidation. Therefore, PNTB is useful for the accurate diagnosis of pulmonary TB in the following cases: airspace consolidation or mass associated with underlying usual interstitial pneumonia, emphysema mimicking lung malignancy or cases of bacterial pneumonia. PMID:25625018

  11. Mesenteric Vascular Occlusion: Comparison of Ancillary CT Findings between Arterial and Venous Occlusions and Independent CT Findings Suggesting Life-Threatening Events

    PubMed Central

    Wu, Cheng-Hsien; Wang, Li-Jen; Chen, Huan-Wu; Lin, Being-Chuan; Huang, Chen-Chih

    2013-01-01

    Objective To compare the ancillary CT findings between superior mesenteric artery thromboembolism (SMAT) and superior mesenteric vein thrombosis (SMVT), and to determine the independent CT findings of life-threatening mesenteric occlusion. Materials and Methods Our study was approved by the institution review board. We included 43 patients (21 SMAT and 22 SMVT between 1999 and 2008) of their median age of 60.0 years, and retrospectively analyzed their CT scans. Medical records were reviewed for demographics, management, surgical pathology diagnosis, and outcome. We compared CT findings between SMAT and SMVT groups. Multivariate analysis was conducted to determine the independent CT findings of life-threatening mesenteric occlusion. Results Of 43 patients, 24 had life-threatening mesenteric occlusion. Death related to mesenteric occlusion was 32.6%. A thick bowel wall (p < 0.001), mesenteric edema (p < 0.001), and ascites (p = 0.009) were more frequently associated with SMVT, whereas diminished bowel enhancement (p = 0.003) and paralytic ileus (p = 0.039) were more frequent in SMAT. Diminished bowel enhancement (OR = 20; p = 0.007) and paralytic ileus (OR = 16; p = 0.033) were independent findings suggesting life-threatening mesenteric occlusion. Conclusion The ancillary CT findings occur with different frequencies in SMAT and SMVT. However, the independent findings indicating life-threatening mesenteric occlusion are diminished bowel wall enhancement and paralytic ileus. PMID:23323029

  12. Indicative findings of pancreatic cancer in prediagnostic CT

    Microsoft Academic Search

    Sung Soo Ahn; Myeong-Jin Kim; Jin-Young Choi; Hye-Suk Hong; Yong Eun Chung; Joon Seok Lim

    2009-01-01

    We examined 20 prediagnostic CTs from 16 patients for whom the diagnosis of pancreatic cancer was delayed until full diagnostic\\u000a CT was performed. Three radiologists independently reviewed the prediagnostic CTs along with 50 CTs of control subjects, including\\u000a patients without pancreatic disease (n?=?38) or with chronic pancreatitis without calcification visible on CT (n?=?12). The reviewers recorded the presence of biliary

  13. Triphasic Helical CT of Hepatic Focal Nodular Hyperplasia: Incidence of Atypical Findings

    Microsoft Academic Search

    Chul Soon Choi; Patrick C. Freeny

    1998-01-01

    OBJECTIVE. The objective of this paper is to assess the findings of focal nodular hyper- plasia of the liver as depicted by triphasic helical CT. MATERIALS AND METHODS. Triphasic helical CT scans (arterial, portal vein, and delayed phase scans) in 12 patients with hepatic focal nodular hyperplasia were reviewed to assess the frequency of findings on each phase. The final

  14. Intense uptake evidenced by 18F-FDG PET/CT without a corresponding CT finding--dream or reality?

    PubMed

    Caobelli, Federico; Pizzocaro, Claudio; Guerra, Ugo Paolo

    2014-01-01

    Although 18F-fluoro-deoxy-glucose (FDG) positron emission tomography (PET) has been widely validated and extensively used in the latest years in clinical practice, interpretation of PET/CT images can be affected by several pitfalls. We here present a case of intense lung uptake in a patient without a corresponding finding on CT images, probably due to a microembolism produced during the injection process and located in small vascular structures of the lung parenchyma. PMID:24610649

  15. CT and MRI of aortic coarctation: pre- and postsurgical findings.

    PubMed

    Karaosmanoglu, Ali Devrim; Khawaja, Ranish Deedar Ali; Onur, Mehmet Ruhi; Kalra, Mannudeep K

    2015-03-01

    OBJECTIVE. The purpose of this article is to summarize the roles of CT and MRI in the diagnosis and follow-up of patients with aortic coarctation. CONCLUSION. Aortic coarctation is a common congenital heart disease accounting for approximately 6-8% of congenital heart defects. Despite its deceptively simple anatomic presentation, it is a complex medical problem with several associated anatomic and physiologic abnormalities. CT and MRI may provide very accurate information of the coarctation anatomy and other associated cardiac abnormalities. PMID:25714305

  16. CT findings in sclerosing mesenteritis (panniculitis): spectrum of disease.

    PubMed

    Horton, Karen M; Lawler, Leo P; Fishman, Elliot K

    2003-01-01

    Sclerosing mesenteritis is a complex inflammatory disorder of the mesentery. Although sclerosing mesenteritis is often associated with other idiopathic inflammatory disorders such as retroperitoneal fibrosis, sclerosing cholangitis, Riedel thyroiditis, and orbital pseudotumor, its exact cause is unknown. The computed tomographic (CT) appearance of sclerosing mesenteritis will vary depending on the predominant tissue component (fat, inflammation, or fibrosis). CT plays an important role in suggesting the diagnosis in the proper clinical setting and can be useful in distinguishing sclerosing mesenteritis from other mesenteric diseases with similar CT features such as carcinomatosis, carcinoid tumor, lymphoma, desmoid tumor, and mesenteric edema. Nevertheless, surgical biopsy and pathologic analysis are usually necessary to make the diagnosis. Treatment may consist of therapy with steroids, colchicine, immunosuppressive agents, or orally administered progesterone. Surgical resection is sometimes attempted for definitive therapy, although the surgical approach is often limited by vascular involvement. CT with three-dimensional volume rendering is optimal for accurate, noninvasive follow-up of sclerosing mesenteritis and of any potential complications. PMID:14615565

  17. Ductal Cysts of the Accessory Lacrimal Glands: CT Findings

    Microsoft Academic Search

    Nabil J. Khoury; Maurice C. Haddad; Ayman N. Tawil; Riad N. Ma' luf

    Summary: Benign ductal cysts of the accessory lacrimal glands are uncommon lesions of the orbit, arising from the glands of Wolfring and Krause. We report two patients with histopathologically proved cysts in whom CT scans revealed well-circumscribed extraconal cystic lesions ad- jacent to the globe, involving both eyelids. Radiologists should be aware of these rare lesions so as to include

  18. Spontaneous vertebral dissection: Clinical, conventional angiographic, CT, and MR findings

    SciTech Connect

    Provenzale, J.M.; Morgenlander, J.C. [Duke Univ. Medical Center, Durham, NC (United States)] [Duke Univ. Medical Center, Durham, NC (United States); Gress, D. [Univ. of California, San Francisco, CA (United States)] [Univ. of California, San Francisco, CA (United States)

    1996-03-01

    The purpose of this study was to determine if typical clinical and neuroradiologic patterns exist in patients with spontaneous vertebral artery (VA) dissection. The medical records and neuroradiologic examinations of 14 patients with spontaneous VA dissection were reviewed. The medical records were examined to exclude patients with a history of trauma and to record evidence of a nontratimatic precipitating event ({open_quotes}trivial trauma{close_quotes}) and presence of possible risk factors such as hypertension. All patients under-went conventional angiography, 13 either CT or MRI (II both CT and MRI), and 3 MRA. Conventional arteriograrris were evaluated for dissection site, evidence of fibromuscular dysplasia, luminal stenosis or occlusion, and pseudoaneurysm formation, CT examinations for the presence of infarction or subarachnoid hemorrhage, MR examinations for the presence of infarction or arterial signal abnormality, and MR angiograms for abnormality of the arterial signal column. Seven patients had precipitating events within 24 h of onset of symptoms that may have been causative of dissection and five had hypertension. At catheter angiography, two patients had dissections in two arteries (both VAs in one patient, VA and internal carotid artery in one patient), giving a total of 15 VAs with dissection. Dissection sites included V1 in four patients, V2 in one patient, V3 in three patients, V4 in six patients, and both V3 and V4 in one patient. Luminal stenosis was present in 13 VAs, occlusion in 2, pseudoaneurysm in 1, and evidence of fibromuscular dysplasia in 1. Posterior circulation infarcts were found on CT or MR in five patients. Subarachnoid hemorrhage was found on CT in two patients and by lumbar puncture alone in two patients. Abnormal periarterial signal on MRI was seen in three patients. MRA demonstrated absent VA signal in one patient, pseudoaneurysm in one, and a false-negative examination in one.

  19. EEG, CT and neurosonographic findings in patients with postischemic seizures

    Microsoft Academic Search

    Susanna Horner; Xiu-Shi Ni; Margret Duft; Kurt Niederkorn; Helmut Lechner

    1995-01-01

    Seventy-two patients with postischemic seizures were evaluated with electroencephalography (EEG), computerized tomography (CT) and neurosonography. There were 24% early-onset and 76% late-onset initial seizures. Early-onset seizure was more likely to be simple partial (53%), whereas late-onset seizure was more likely to be primarily generalized (56%). 76% early-onset and 80% late-onset seizures were single. Status epilepticus was more frequent in early-onset

  20. Ependymomas of the posterior cranial fossa: CT and MRI findings

    Microsoft Academic Search

    P. Tortori-Donati; M. P. Fondelli; A. Cama; M. L. Garrè; A. Rossi; L. Andreussi

    1995-01-01

    We studied nine children with posterior cranial fossa ependymomas to identify specific neuroradiological features. Patients were studied preoperatively with CT and MRI; T1-, T2-and proton-density (PD)-weighted images were obtained. All children underwent surgery and a definite histopathological diagnosis was made. All the tumours grew into the fourth ventricle and caused dilatation of its upper part, which resembled a cap. All

  1. Ependymomas of the posterior cranial fossa: CT and MRI findings

    Microsoft Academic Search

    P. Tortori-Donati; M. P. Fondelli; A. Cama; M. L. Garrè; A. Rossi; L. Andreussi

    1995-01-01

    We studied nine children with posterior cranial fossa ependymomas to identify specific neuroradiological features. Patients were studied preoperatively with CT and MRI; T1-, T2- and proton-density (PD)-weighted images were obtained. All children underwent surgery and a definite histopathological diagnosis was made. All the tumours grew into the fourth ventricle and caused dilatation of its upper part, which resembled a cap.

  2. Atlanto-odontoid osteoarthritis in rheumatoid arthritis: dynamic CT findings.

    PubMed

    Baysal, Ozlem; Baysal, Tamer; Sigirci, Ahmet; Ersoy, Yuksel; Altay, Zuhal

    2004-10-01

    We analyzed the CT appearances of degenerative change in the atlanto-odontoid joint (AOJ) in patients with rheumatoid arthritis (RA) and evaluated the effect of these changes on atlanto-axial joint (AAJ) rotation by dynamic CT. This revealed that 9 patients (24%) treated with methotrexate had degenerative features in the AOJ. The ratio of AAJ rotation to the total rotation of the cervical spine was significantly higher in normal subjects (54 +/- 3%) than in patients (38 +/- 12%). The degree of AAJ rotation was significantly lower in the patient group with degenerative features in the AOJ (20.9 +/- 8.4 degrees ) than in patients without degenerative features (28.5 +/- 7.4 degrees ). RA patients with a history of longstanding disease and treatment with antirheumatic drugs may develop AO OA. Although secondary OA was described as healing phenomena in the joints of RA patients, it can limit rotation in the AAJ and cause suboccipital neck pain. A regular check-up of the AAJ and AOJ by means of dynamic CT in all RA patients is proposed to avoid possible antirheumatic drug complications. PMID:15459811

  3. CT findings in ten patients with failed renal allografts: comparison with findings in functional grafts

    Microsoft Academic Search

    Gabriela Gayer; Sara Apter; Rama Katz; Aharon Ben-David; Ze'ev Katzir; Marjorie Hertz

    2000-01-01

    Our aim is to report the computed tomography (CT) features of the long-term failed renal allograft. Ten patients with failed renal transplants in whom the graft was left in situ underwent CT for various unrelated indications. The majority of the failed grafts showed marked shrinkage and coarse punctate diffuse parenchymal calcifications. Small cysts were seen in four grafts. A long-term

  4. Unenhanced Helical CT of Ureteral Stones: Incidenceof Associated UrinaryTractFindings

    Microsoft Academic Search

    Douglas S. Katz; F Graham Sommer

    OBJECTIVE. The objective of this study was to determine the incidence of urinary tract findings associated with ureteral stones on unenhanced helical CT scans of patients with acute renal colic. MATERIALS AND METHODS. One hundred forty-one consecutive patients with suspected renal colic were referred by the emergency department for a helical CT scan that was obtained without oral or IV

  5. CT findings in malignant pleural mesothelioma related to nonoccupational exposure to asbestos and fibrous zeolite (erionite)

    Microsoft Academic Search

    Canan Erzen; Muzaffer Eryilmaz; Fuat Kalyoncu; Nazmi Bilir; Altan Sahin; Y. Izettin Baris

    1991-01-01

    Endemic malignant pleural mesothelioma (MPM) in Turkey is related to two mineral fibers, tremolite asbestos and fibrous zeolite (erionite). Thirteen cases of MPM from the Cappadocian area, where the soil is rich in erionite, and 29 cases of MPM, from villages whose occupants have high asbestos exposure, were examined by CT. The CT findings of the two groups of MPM

  6. CT findings in symptomatic Rathke's cleft cysts of the pituitary gland

    Microsoft Academic Search

    J. L. Dietemann; J. F. Bonneville; F. Buchheit; F. Cattin; N. Heldt; A. Wackenheim

    1983-01-01

    Symptomatic intrasellar Rathke's cleft cysts are rather rare: only a few cases with CT findings have been reported. The authors describe the CT appearance of 3. Histological aspects and embryology are discussed. Rathke's cleft cysts have to be differentiated from other intrasellar tumours: cystic craniopharyngiomas, cystic or necrotic pituitary adenomas, cysticercosis.

  7. CT findings in metastatic ovarian tumors from gastrointestinal tract neoplasms (Krukenberg tumors)

    Microsoft Academic Search

    J. M. Mata; L. Inaraja; A. Rams; J. Andreu; L. Donoso; G. Marcuello

    1988-01-01

    The computed tomographic (CT) findings are reviewed in 7 patients with metastatic ovarian tumors from gastrointestinal tract neoplasms (Krukenberg tumors). All patients presented mixed ovarian masses. In 6 cases the masses were mainly cystic, with internal septa and focal or uniform enlargement of the cyst wall. In the seventh patient the ovarian mass appeared on the CT as mainly solid.

  8. Unusual CT Hyperattenuating Dermoid Cyst of Cerebellum: A New Case Report and Literature Review

    Microsoft Academic Search

    Zhao-Jian Li; Yuan-Xin Miao; Peng Sun; Yu-Jun Li; Yi-He Dou; Jian Xu; Xin Chen; Yun-Xia Jiang

    Almost all intracranial dermoid cysts typically display low-density lesions on plain computerized tomography (CT) scans due\\u000a to abundant lipids content. CT hyperattenuating dermoid cyst (CHADC) is very uncommon with only nine case reports in the literature\\u000a update, which occurs exclusively in the posterior fossa. Moreover, CHADC with mural nodule is exceptionally rare, and only\\u000a one such case was documented previously.

  9. Role of CT Colonography in Colonic Lesions and Its Correlation with Conventional Colonoscopic Findings

    PubMed Central

    Singh, Kunwarpal; Thukral, Chuni Lal; Singh, Neeti Rajan; Singh, Amandeep; Kaur, Harmeet

    2015-01-01

    Background Preoperative evaluation in patients with colorectal carcinoma is essential for a correct therapeutic plan. Conventional colonoscopy has certain limitations including its inability to detect synchronous lesions in case of distal obstructive mass and inaccurate tumour localization. CT colonography combines cross sectional imaging with virtual colonoscopic images and offers a comprehensive preoperative evaluation in patients with colorectal carcinoma including detection of synchronous lesions with accurate segmental localization and loco regional staging. Aim The objective was to determine the role of CT colonography in various colonic lesions and to correlate the findings with conventional colonoscopy and histopathological findings. Settings and Design This prospective study included 50 patients with clinical symptoms suspicious of colonic pathology. Materials and Methods All the patients underwent both CT colonography and conventional colonoscopy on the same day. CT colonography was performed in supine and prone position. Considering histopathological and/or surgical findings as gold standard, sensitivity and specificity of both the modalities were calculated. Results Conventional colonoscopy missed two synchronous lesions proximal to occlusive mass and one lesion proximal to the anastomotic site; all were detected with CT colonography. One carpet lesion in rectum and one case of mild ulcerative colitis were missed by CT colonography. Sensitivity and specificity for detection of colorectal cancer were 97.56% and 100%, resp. with PPV and NPV of 100% and 93.75%, for CT colonography and 92.68% and 100%, respectively with PPV and NPV of 100% and 83.3% for conventional colonoscopy. Sensitivity for correct detection of acute and chronic ulcerative colitis of CT colonography was 66.6 % and 100 %, resp. Conclusion CT colonography has higher sensitivity than conventional colonoscopy for detection of colorectal carcinoma, including its ability to detect abnormalities proximal to obstructing lesion, accurate segmental localization of lesions and staging. However, some limitations of CT colonography were difficulty in detection of flat lesions and lack of information about hyperemia and superficial mucosal erosion, where conventional colonoscopy scored over CT colonography. PMID:26023619

  10. 18F-FDG PET/CT Findings in a Splenic Lymphangioma.

    PubMed

    Ji, Ting; Kuang, Anren

    2015-07-01

    A 16-year-old girl with abdominal pain for 3 years underwent FDG PET/CT scan for evaluating identifiable origin. The images showed multifocal, subcapsular thin-walled low-attenuation masses on CT and focal, slight increased F-FDG uptake on PET with an SUVmax of 3.0. Based on the findings, malignancy cannot be excluded. Then, pathologic examination was performed, and it was identified to be splenic lymphangioma. We herein presented the FDG PET/CT findings of this splenic lymphangioma, which is a rare benign vascular tumor and commonly caused by congenital malformation of the lymphatic vessels. PMID:26018722

  11. Esophageal early basaloid squamous carcinoma with unusual narrowband imaging magnified endoscopy findings

    PubMed Central

    Kai, Yugo; Kato, Motohiko; Hayashi, Yoshito; Akasaka, Tomofumi; Shinzaki, Shinichiro; Nishida, Tsutomu; Tsujii, Masahiko; Morii, Eiichi; Takehara, Tetsuo

    2014-01-01

    Basaloid squamous carcinoma (BSC) is a rare variant of esophageal cancer. There are very few reports of “early” BSC. Here we report a case of early BSC with unusual findings by narrowband imaging magnified endoscopy (NBI-ME). A 70-year-old man with a middle thoracic esophageal tumor was referred to our hospital. White-light endoscopy revealed a reddish depressed lesion 5 mm in diameter having a subepithelial tumor-like prominence with a gentle rising slope. NBI-ME revealed irregular loop-shaped microvessels coexistent with thick irregularly branched non-looped vessels. Iodine staining revealed a pale brown lesion. We performed endoscopic submucosal dissection for diagnostic treatment. Histologic examination showed the proliferation of basal cell-like hyperchromatic tumor cells in the lamina propria and with slight invasion into the submucosa at a depth of 320 ?m. The tumor cells formed solid nests and microcystic structures, containing an Alcian blue-positive mucoid matrix. The surface was covered with squamous epithelium without cellular atypia. Thin vessels were observed in the intra-epithelial papilla and thick vessels were observed around the solid nests beneath the epithelium. Based on these findings together, we diagnosed the lesion as BSC. In this case, the NBI-ME findings differed from those of typical squamous cell carcinoma in that both non-invasive cancer-like irregular loop-shaped microvessels coexisted with massively invasive cancer-like thick non-looped vessels. We speculate that the looped and non-looped vessels observed by NBI-ME histologically corresponded to thin vessels in the intra-epithelial papilla and thick vessels around the tumor nests, respectively. These NBI-ME findings might be a feature of early esophageal BSC. PMID:25253974

  12. Airways obstruction in patients with sarcoidosis: expiratory CT scan findings.

    PubMed

    Bartz, R R; Stern, E J

    2000-10-01

    In patients with pulmonary sarcoidosis, air trapping as evidenced by expiratory high-resolution computed tomography (HRCT) is not specific for a given stage of disease. Air trapping can occur at the level of the secondary lobule, as well as in distributions suggesting sublobular, subsegmental, and segmental involvement. While air trapping can be a nonspecific finding, it is a common feature in patients with pulmonary sarcoidosis and is a supportive diagnostic finding. PMID:11039617

  13. Spontaneous rupture of a hepatic angiomyolipoma: CT findings and literature review

    Microsoft Academic Search

    G. Guidi; O. Catalano; A. Rotondo

    1997-01-01

    .   Angiomyolipoma is an uncommon lipomatous neoplasm of the liver, usually asymptomatic and identified incidentally. We describe\\u000a the CT findings of a surgically confirmed case of spontaneously ruptured angiomyolipoma with evidence of internal hemorrhage\\u000a and hemoperitoneum. The CT features were that of an exophitic, oval, well-defined mass with inhomogeneous attenuation values\\u000a due to the presence of fat- and soft-tissue densities.

  14. Spectrum of CT findings in nonmalignant disease of the adrenal gland.

    PubMed

    Kawashima, A; Sandler, C M; Fishman, E K; Charnsangavej, C; Yasumori, K; Honda, H; Ernst, R D; Takahashi, N; Raval, B K; Masuda, K; Goldman, S M

    1998-01-01

    Computed tomography (CT) plays a leading role in the evaluation of nonmalignant disease of the adrenal gland. CT is highly accurate in the localization of adrenal masses in patients with diseases associated with hyperfunctioning adrenal glands such as Cushing syndrome and Cushing disease, Conn syndrome, adrenal tumors leading to virilization or feminization, and pheochromocytomas. CT permits a specific diagnosis of acute or subacute adrenal hematoma and myelolipoma. Hematomas are round to oval and have increased attenuation (50-90 HU) that decreases on follow-up CT scans. Myelolipomas typically manifest as a well-defined suprarenal mass with an attenuation of-30 to -115 HU. Adrenal cysts are usually round to oval and manifest as a hypoattenuating mass with a smooth, thin wall. CT is useful in the evaluation of patients with Addison disease, particularly the subacute form secondary to tuberculosis or disseminated histoplasmosis. Findings typically include bilateral adrenal enlargement with a central necrotic area of hypoattenuation and peripheral enhancement. Thin-section unenhanced CT permits accurate measurement of attenuation and can be used to differentiate adrenal adenoma from metastasis in a cancer patient with an indeterminate mass: Attenuation of 10 HU or less usually indicates adenoma rather than cancer. If the mass is found incidentally at contrast material-enhanced CT, delayed scans obtained as early as 5-15 minutes after intravenous administration of contrast material appear to have comparable accuracy. PMID:9536486

  15. Early Recurring Hepatocellular Carcinoma after Partial Hepatic Resection: Preoperative CT Findings

    PubMed Central

    Jang, Hyun-Jung; Kim, Eung Yeop; Park, Cheol Keun; Joh, Jae-Won; Kim, Yong Il

    2000-01-01

    Objective The purpose of this study was to determine the utility of preoperative CT in predicting early recurrence of hepatocellular carcinoma after partial hepatic resection. Materials and Methods Preoperative three-phase helical CT scans in 53 patients with hepatocellular carcinoma were retrospectively reviewed by two radiologists. In 27 patients (group I), HCC had recurred within six months, while 26 (group II) had remained disease free for at least two years. In each group, preoperative CT findings were evaluated in each group for the tumor size and number, the presence or absence of capsule, distinctness of tumor margin, perinodular extension, and the presence or absence of portal vein thrombosis. Results In group I, a tumor capsule of tumor was seen in five of 27 patients (19%), and in group II, in 16 of 26 (62%) (p = .001). The tumor margin was distinct in eight patients (30%) in group I and in 20 (77%) in group II (p = .001). Multiple tumors, perinodular extension, and portal vein thrombosis were more frequently seen in group I but the differences were not statistically significant (p > .05). Tumor size was similar in each group (p > .05). Conclusion Preoperative CT findings that may help predict the early recurrence of hepatocellular carcinoma after surgical resection are an absence of capsule of tumors and an indistinct margin. Reference to these findings during preoperative CT can guide clinicians in their choice of treatment. PMID:11752927

  16. [Hypoglycemic encephalopathy demonstrating generalized multiple cortical infarctions--sequential CT findings].

    PubMed

    Isono, O; Araki, S; Shiota, J; Toyota, S; Sugita, K

    1993-11-01

    A fifty-nine-year-old alcoholic man with severe hypoglycemic encephalopathy was examined using sequential CT scans of the brain (CT). Twenty-seven hours after the attack, which resulted in a comatose state, CT disclosed multiple low density areas throughout the cerebral cortex which resembled multiple cortical infarctions. CT obtained four days after the ictus demonstrated more prominent low density areas in the cerebral cortex, diffuse cerebral edema and partial cortical enhancement after administration of contrast medium. Sixteen days after the ictus, the multiple low density areas in the cerebral cortex disappeared. Enhanced CT on day 23 demonstrated marked gyral enhancement throughout the cerebral cortex. Thereafter diffuse brain atrophy progressed rapidly as demonstrated by MRI on day 82 which showed extensive cortical and subcortical atrophy particularly in the frontoparietal and parieto-occipital regions bilaterally with dilated lateral ventricles. Hypoglycemia and anoxia have long been thought to give rise to similar types of brain damage based on neuropathological observations. But it has recently been shown that they are quite different based on neurochemical and neurophysiological findings. Numerous previously reported autopsy cases of hypoglycemia confirm these findings which are neuropathologically similar to the multiple infarction seen in the present case. We conclude that the acute cortical changes of the present case are specific for hypoglycemic encephalopathy. The findings indicate that the basic mechanisms operating in hypoglycemia and anoxia are different. PMID:8297667

  17. Correlation between PET/CT results and histological and immunohistochemical findings in breast carcinomas*

    PubMed Central

    Bitencourt, Almir Galvão Vieira; Lima, Eduardo Nóbrega Pereira; Chojniak, Rubens; Marques, Elvira Ferreira; de Souza, Juliana Alves; Graziano, Luciana; Andrade, Wesley Pereira; Osório, Cynthia Aparecida Bueno de Toledo

    2014-01-01

    Objective To correlate the results of 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) performed with a specific protocol for assessment of breasts with histological/immunohistochemical findings in breast carcinoma patients. Materials and Methods Cross-sectional study with prospective data collection, where patients with biopsy-confirmed breast carcinomas were studied. The patients underwent PET/CT examination in prone position, with a specific protocol for assessment of breasts. PET/CT findings were compared with histological and immunohistochemical data. Results The authors identified 59 malignant breast lesions in 50 patients. The maximum diameter of the lesions ranged from 6 to 80 mm (mean: 32.2 mm). Invasive ductal carcinoma was the most common histological type (n = 47; 79.7%). At PET/CT, 53 (89.8%) of the lesions demonstrated anomalous concentrations of 18F-FDG, with maximum SUV ranging from 0.8 to 23.1 (mean: 5.5). A statistically significant association was observed between higher values of maximum SUV and histological type, histological grade, molecular subtype, tumor diameter, mitotic index and Ki-67 expression. Conclusion PET/CT performed with specific protocol for assessment of breasts has demonstrated good sensitivity and was associated with relevant histological/immunohistochemical factors related to aggressiveness and prognosis of breast carcinomas. PMID:25741051

  18. CT and MR Findings of Anthrax Meningoencephalitis: Report of Two Cases and Review of the Literature

    Microsoft Academic Search

    Hak Jin Kim; Woong Bae Jun; Suck Hong Lee; Myung Ho Rho

    Summary: Anthrax meningoencephalitis is a rare compli- cation of infection with Bacillus anthracis and generally produces a hemorrhagic meningoencephalitis. We present the CT and MR imaging findings in two patients demon- strating subarachnoid, intracerebral, and intraventricular hemorrhage with leptomeningeal enhancement. Infection with the Bacillus anthracis, a large gram-positive, spore-forming bacillus transmitted to humans by contact with infected animals or con-

  19. Misty mesentery: a pictorial review of multidetector-row CT findings.

    PubMed

    Filippone, A; Cianci, R; Di Fabio, F; Storto, M L

    2011-04-01

    The term "misty mesentery" indicates a pathological increase in mesenteric fat attenuation at computed tomography (CT). It is frequently observed on multidetector CT (MDCT) scans performed during daily clinical practice and may be caused by various pathological conditions, including oedema, inflammation, haemorrhage, neoplastic infiltration or sclerosing mesenteritis. In patients suffering from acute abdominal disease, misty mesentery may be considered a feature of the underlying disease. Otherwise, it may represent an incidental finding on MDCT performed for other reasons. This article describes the MDCT features of misty mesentery in different diseases in order to provide a rational approach to the differential diagnosis. PMID:21311992

  20. Samonella-and Shigella-induced ileitis: CT findings in four patients

    SciTech Connect

    Balthazar, E.J.; Charles, H.W.; Megibow, A.J. [New York Univ. Tisch-Bellevue Medical Center, New York, NY (United States)] [New York Univ. Tisch-Bellevue Medical Center, New York, NY (United States)

    1996-05-01

    The purpose of this study is to describe and illustrate the CT appearance of four cases of acute terminal ileitis induced by nontyphoidal Salmonella and Shigella infection and to review the radiographic and endoscopic findings of these entities. The medical records, CT examinations, and small bowel examinations of three patients with Salmonella ileitis and one patient with Shigella ileitis were retrospectively reviewed. CT examinations were done in four patients, colonoscopy in three patients, and small bowel examinations in two patients. Stool cultures established the diagnosis of nontyphoidal Salmonella enteritis in three patients and Shigella enteritis in one patient. The patients symptoms and clinical findings resolved promptly following supportive therapy and appropriate antibiotic therapy. CT showed slight circumferential and homogeneous thickening of the terminal ileum over a segment of 10-15 cm in patients with Salmonella ileitis. Associated mild thickening of the wall of the colon was present in addition. Small bowel examination performed in one patient revealed a spastic terminal ileum with thickened mucosal folds. Colonoscopy revealed acute colitis involving the colon diffusely in one case, but sparing the distal 50 cm of the colon in one case. CT showed more pronounced thickening of the terminal ileum and a target configuration in the patient with Shigella ileitis. Small bowel examination revealed narrowing, irregular contour, several large nodular defects, and a severely ulcerated mucosa affecting the terminal ileum. Colonoscopy revealed a normal colon and large ulcerations with fibro-purulent exudate in the terminal ileum. In patients with severe Salmonella or Shigella infections or persistent and/or confusing clinical presentations, CT can play a complementary but important role in the initial diagnostic evaluation. 20 refs., 2 figs.

  1. Unusual Malignant Coronary Artery Anomaly: Results of Coronary Angiography, MR Imaging, and Multislice CT

    SciTech Connect

    Apitzsch, Jonas, E-mail: apitzsch@rad.rwth-aachen.d [RWTH Aachen University, Department of Diagnostic Radiology (Germany); Kuehl, Harald P. [RWTH Aachen University, Department of Cardiology (Germany); Muehlenbruch, Georg; Mahnken, Andreas H. [RWTH Aachen University, Department of Diagnostic Radiology (Germany)

    2010-04-15

    We report the case of a man with an uncommon anomaly of the origin and course of the left coronary artery. Clinical, coronary angiography, magnetic resonance imaging, and multislice computed tomography findings of this intermittently symptomatic 49 year-old patient with the rare anomaly of his left coronary artery stemming from the right sinus of Valsalva and taking an interarterial and intraseptal course are presented. The diagnostic value of the different imaging modalities is discussed.

  2. Incidental findings on positron emission tomography/CT scans performed in the investigation of lung cancer

    PubMed Central

    Chopra, A; Ford, A; De Noronha, R; Matthews, S

    2012-01-01

    Objectives This study aimed to clarify the number and cause of incidental findings detected on positron emission tomography (PET)/CT in patients undergoing investigation for presumed lung cancer. Methods The scan reports from PET/CT studies performed for patients with lung cancer under National Institute for Clinical Evidence guidelines from January 2006 until March 2008 were retrospectively reviewed. Incidental findings were followed up by a combination of case note review, clinician feedback, colonoscopy database, histopathology and follow-up imaging. Results 818 patients were investigated for lung cancer in the study period. 197 incidental findings were found in 175 (21%) patients. The subsequent investigation of 108 lesions confirmed a pathological correlation in 71 (66%) cases. A second primary malignancy was found in 10 patients within the bowel (6), breast (2), tongue (1) and stomach (1). A pre-malignant lesion was confirmed in 25 cases (24 large bowel tubulovillous adenomas and a follicular thyroid lesion). A further 41 (5%) benign abnormalities were detected at multiple sites; the thyroid gland was the single most frequently affected site (14 abnormalities). There were 36 (4.4%) false-positive reported findings, including 17 in the region of the pharynx and larynx and 12 within the large bowel. Conclusions Overall, 9.2% of patients with suspected or known lung cancer having PET/CT had a confirmed incidental finding. A malignant or pre-malignant lesion was found in 1.2% and 3.0%, respectively. These were mostly located within the gastrointestinal tract. The majority of false-positive incidental findings were located in the larynx and pharynx. Uptake in these regions is unlikely to be significant in the absence of a CT morphological correlation. PMID:22745208

  3. Orbital positron emission tomography/computed tomography (PET/CT) imaging findings in graves ophthalmopathy

    PubMed Central

    2013-01-01

    Background We aimed to describe orbital positron emission tomography/computed tomography (PET/CT) imaging findings, both structural and metabolic, in different clinical stages of Graves ophthalmopathy (GO). This prospective, observational, cross-sectional study examined 32 eyes of 16 patients with GO. Methods Patients were assessed with a complete ophthalmological evaluation and assigned a VISA classification for GO. All patients underwent serum thyroid hormone measurement, antibody profile, and 18-fluorodeoxyglucose positron emission tomography/computed tomography (18-FDG PET/CT) of the orbits. The 18-FDG uptake on PET images was expressed in terms of maximum standard uptake value (SUVmax). CT images were analyzed, and orbital structures were measured in millimeters. Vision, inflammation, strabismus, and overall appearance were assessed according to the VISA classification system, thyroid hormone levels, antibody values, 18-FDG uptake, and thickness of orbital structures. Results Altogether, 32 eyes of 16 patients (10 women, 6 men; mean age 44.31?±?13 years, range 20–71 years) were included. Three patients were hypothyroid, seven were euthyroid, and six were hyperthyroid. CT measurements of extraocular muscle diameter were elevated (P?CT (R2?=?0.0755, P?>?0.05). Conclusions We demonstrated a lack of correlation between 18-FDG extraocular muscle uptake and either clinical inflammation score or muscle diameter. Although 18-FDG uptake has been used as an inflammation marker in other pathologies, inflammation in GO may be clinically detected in PET/CT-negative cases, and cases with negative clinical findings may show inflammation on PET/CT. Clinical evaluation is mandatory but may be insufficient and inaccurate for classifying GO. A larger and homogeneous sample size and further research is needed to define the role of PET/CT in detecting, grading, and follow-up of GO to optimize treatment of the inflammatory stage respect clinical methods currently used. PMID:24007404

  4. Ischemic colitis: spectrum of CT findings, sites of involvement and severity.

    PubMed

    Cruz, Cinthia; Abujudeh, Hani H; Nazarian, Rosalynn M; Thrall, James H

    2015-08-01

    To summarize the frequency of findings on IV contrast, enhanced computer tomography (CT) in 335 patients with pathologically proven ischemic colitis (IC) determine the most frequent locations and patterns of involvement and establish the correlation of these findings with the severity of IC. 231 patients were excluded for not having a concomitant CT or for having underlying comorbidities. 104 cases were analyzed. Scans were evaluated for abnormal wall enhancement (AE), bowel wall thickening (BWT), bowel dilatation (DIL), mesenteric fat stranding (FS), venous engorgement (VE), pericolonic free fluid (FF), and pneumatosis (PN) and portomesenteric venous gas. Segmental versus pancolonic involvement was noted. Severity was determined by histopathology criteria. Data obtained are as follows: female to male incidence, 69 % (70) vs. 31 % (34); average age, 64.5; and positive CT, 102/104 (98.1 %). The most frequent findings include FS (88 %), BWT (88 %), and AE (82 %) regardless of severity of involvement. Statistically significant increased risk ratio and likelihood of severe ischemia for PN, DIL, and FF individually. BWT, DIL, FS, FF, VE, and PN together have a probability for severe IC of 91.8 %. A correlation between fewer findings and milder IC was found (R (2)?=?0.6771). The most frequently involved segments: descending (64 %) and sigmoid colon (54 %). Splenic flexure (SF) was infrequently involved (n?=?8, 7.84 %). Females had two times higher incidence of IC. The most frequent CT findings in IC are FS, BWT, and AE regardless of the severity. PN is suggestive of severe IC. Segmental involvement is the predominant pattern. The distal colon is more frequently involved. SF contrary to the conventional literature is not disproportionately involved in IC. PMID:25732355

  5. Common and unusual diseases involving the iliopsoas muscle compartment: spectrum of cross-sectional imaging findings

    Microsoft Academic Search

    Massimo Tonolini; Alessandro Campari; Roberto Bianco

    Although relatively uncommon, many different infectious, hemorrhagic and neoplastic disease processes may involve the iliac\\u000a and psoas muscles and are increasingly diagnosed especially in referral hospitals. Furthermore, the iliopsoas compartment\\u000a may become injured during trauma, percutaneous instrumentation, laparoscopic or open surgical procedures. State-of-the-art\\u000a cross-sectional imaging including volumetric multidetector CT and multiplanar MRI acquisitions allows prompt detection, comprehensive\\u000a visualization and confident

  6. Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus

    PubMed Central

    Ishii, Mitsuaki; Kawamata, Toshio; Akiguchi, Ichiro; Yagi, Hideo; Watanabe, Yuko; Watanabe, Toshiyuki; Mashimo, Hideaki

    2010-01-01

    We aimed to investigate the characteristics of Parkinsonian features assessed by the unified Parkinson's disease rating scale (UPDRS) and determine their correlations with the computed tomography (CT) findings in patients with idiopathic normal pressure hydrocephalus (iNPH). The total score and the scores for arising from chair, gait, postural stability, and body hypokinesia in the motor examination section of UPDRS were significantly improved after shunt operations. Stepwise multiple regression analysis revealed that postural stability was the determinant of the gait domain score of the iNPH grading scale. The canonical correlation analysis between the CT findings and the shunt-responsive Parkinsonian features indicated that Evans index rather than midbrain diameters had a large influence on the postural stability. Thus, the pathophysiology of postural instability as a cardinal feature of gait disturbance may be associated with impaired frontal projections close to the frontal horns of the lateral ventricles in the iNPH patients. PMID:20948890

  7. Abnormal Ocular Enhancement in Sturge-Weber Syndrome: Correlation of Ocular MR and CT Findings with Clinical and Intracranial Imaging Findings

    Microsoft Academic Search

    Paul D. Griffiths; Mitra B. Boodram; Susan Blaser; Filiberto Altomare; J. Raymond Buncic; Alex V. Levin; Venita Jay; Derek Armstrong; Derek Harwood-Nash

    PURPOSE: To estimate the prevalence of abnormal ocular enhancement in children with Sturge- Weber syndrome as detected with MR imaging and CT and to correlate this with the clinical, fundoscopic, and intracranial imaging findings. METHODS: Fifteen children, 4 years old or younger, with Sturge-Weber syndrome were examined with enhanced CT and MR imaging. Eleven children had unilateral intracranial involvement and

  8. US, CT and MRI findings in a case of diffuse lymphangiomatosis and cystic hygroma

    PubMed Central

    Ozel, A.; Uysal, E.; Dokucu, A.I.; Erturk, S.M.; Basak, M.; Cantisani, V.

    2008-01-01

    Lymphangiomatosis is a rare disease with multifocal lymphatic proliferation that typically occurs during childhood and involves multiple parenchymal organs including the lung, liver, spleen, bone, and skin. Lymphangiomatosis may occur synchronously or metachronously with cystic hygroma of the neck. We present US, CT, and MRI findings of cystic hygroma of the neck associated with generalized lymphangiomatosis affecting bones and spleen in a 2-year-old girl. PMID:23396953

  9. Small bowel obstruction due to phytobezoar formation within meckel diverticulum: CT findings

    SciTech Connect

    Frazzini, V.I. Jr.; English, W.J.; Bashist, B.; Moore, E. [Columbia Univ. College of Physicians and Surgeons, New York, NY (United States)] [Columbia Univ. College of Physicians and Surgeons, New York, NY (United States)

    1996-05-01

    Intestinal obstruction due to a phytobezoar within a Meckel diverticulum is exceedingly rare, with only seven reported cases in the surgical literature. The most important precipitating factor is the ingestion of agents high in fiber and cellulose. Small bowel obstruction in all but one case was due to retrograde propagation of the bezoar into the small bowel lumen. We report the clinical and CT findings in such a patient following a vegetarian diet. 14 refs., 2 figs.

  10. CT and MR findings of Krukenberg tumors: Comparison with primary ovarian tumors

    SciTech Connect

    Kim, Seung Hyup; Kim, Won Hong; Park, Kyung Joo [Seoul National Univ. (Korea, Republic of)] [Seoul National Univ. (Korea, Republic of)

    1996-05-01

    The purposes of this study were to evaluate the CT and MR findings of Krukenberg tumors and to compare them with those of primary ovarian tumors. This study included 20 patients with Krukenberg tumors and 65 patients with various primary ovarian tumors. CT/MR/both imaging studies were available in 15/1/4 patients with Krukenberg tumor and 31/10/24 patients with primary ovarian tumors, respectively. Imaging findings of the tumors were categorized into three subgroups: a solid mass with intratumoral cysts, a solid mass without intratumoral cysts, and a predominantly cystic mass. Among 32 Krukenberg tumors (bilateral in 12 patients), 22 were solid masses with intratumoral cysts, in 14 of which the wall of the intratumoral cysts showed apparently strong contrast enhancement on CT and/or MRI. Six Krukenberg tumors were solid masses without intratumoral cysts, and four were predominantly cystic masses. Imaging findings of 88 primary ovarian tumors (bilateral in 23 patients) were 5 solid masses with intratumoral cysts, 27 solid masses without intratumoral cysts, and 56 predominantly cystic masses. None of the five primary ovarian tumors with solid mass with intratumoral cysts demonstrated apparently strong contrast enhancement of the cyst wall. Krukenberg tumor should be suspected when one sees solid ovarian tumors containing well demarcated intratumoral cystic lesions, especially if the walls of those cysts demonstrate apparently strong contrast enhancement. 11 refs., 4 figs., 1 tab.

  11. Common and unusual urogenital Crohn's disease complications: spectrum of cross-sectional imaging findings.

    PubMed

    Tonolini, Massimo; Villa, Chiara; Campari, Alessandro; Ravelli, Anna; Bianco, Roberto; Cornalba, Gianpaolo

    2013-02-01

    Involvement of the urinary tract and genital organs is not uncommon in patients affected with Crohn's disease (CD). Occurring in both sexes, uro-gynecological complications are often clinically unsuspected because of the dominant intestinal or systemic symptoms. Knowledge of their manifestations and cross-sectional imaging appearances is necessary to recognize and report them, since correct medical or surgical treatment choice with appropriate specialist consultation allows to prevent further complications. Besides uncomplicated urinary tract infections that usually do not require imaging, urolithiasis and pyelonephritis represent the most commonly encountered urinary disorders: although very useful, use of computed tomography (CT) should be avoided whenever possible, to limit lifetime radiation exposure. Hydronephrosis due to ureteral inflammatory entrapment and enterovesical fistulization may result from penetrating CD, and require precise imaging assessment with contrast-enhanced CT to ensure correct surgical planning. Representing the majority of genital complication, ano- and rectovaginal fistulas and abscesses frequently complicate perianal inflammatory CD and are comprehensively investigated with high-resolution perianal MRI acquired with phased-array coils, high-resolution T2-weighted sequences and intravenous contrast. Finally, rare gynecological manifestations including internal genital fistulas, vulvar and male genital involvement are discussed. PMID:22456714

  12. Gastrointestinal tract lymphangiomas: findings at CT and endoscopic imaging with histopathologic correlation

    Microsoft Academic Search

    Hui Zhu; Zhi Yuan Wu; Xiao Zhu Lin; Bei Shi; Manavendra Upadhyaya; Kemin Chen

    2008-01-01

    Objective  To evaluate and describe CT and endoscopic imaging findings in patients with pathologically confirmed gastrointestinal tract\\u000a lymphangiomas.\\u000a \\u000a \\u000a \\u000a Methods  Findings from imaging examinations in 6 patients with pathologically confirmed lymphangioma were retrospectively reviewed\\u000a (computed tomographic images obtained in 6 patients and endoscopic images obtained in 4 patients were available for review).\\u000a Two radiologists evaluated lesion location, size, shape, edge, number, attenuation, the

  13. Multiphasic contrast-enhanced CT and MRI findings of adult mesoblastic nephroma: A report of two cases

    PubMed Central

    Ding, Yuqin; He, Deming; Zhou, Jianjun; Zeng, Mengsu

    2013-01-01

    Mesoblastic nephroma (MN) presenting in an adult is extremely rare. The computed tomography (CT) and magnetic resonance imaging (MRI) features of this tumor in adulthood have not been widely reported. We present two additional cases of adult MN and describe the multiphasic contrast-enhanced CT and MRI findings. PMID:23986620

  14. Unusual retrospective prenatal findings in a male newborn with Timothy syndrome type 1.

    PubMed

    Corona-Rivera, J Román; Barrios-Prieto, Ernesto; Nieto-García, Rafael; Bloise, Raffaella; Priori, Silvia; Napolitano, Carlo; Bobadilla-Morales, Lucina; Corona-Rivera, Alfredo; Zapata-Aldana, Eugenio; Peña-Padilla, Christian; Rivera-Vargas, Jehú; Chavana-Naranjo, Eva

    2015-01-01

    Timothy syndrome 1 (TS1) is a multisystem disorder characterized by severe QT prolongation and potentially lethal ventricular arrhythmias in the first years of life, plus other cardiac and extracardiac manifestations caused by mutation in the CACNA1C gene, a CaV1.2 L-type calcium channel. Here, we report retrospectively an unusual fetal presentation on a second patient with TS1 with fetal hydrops due to a congenital AV block and its postnatal diagnosis by a marked prolongation of the corrected QTc interval of 570 ms and a missense mutation, p.Gly406Arg, in exon 8A of CACNA1C gene. The observed manifestations in our patient during fetal period indicate a severe form and they were probably exacerbated by the maternal use of amitriptyline during the first 4 months of pregnancy. Unfortunately, he died at 3 months-old due a ventricular tachycardia and fibrillation related to a septic event. Although difficult to diagnose, possibly most fetuses with TS1 have symptoms of long QT syndrome. Despite the fatal outcome for our patient, an early diagnosis of TS may help to prevent life-threatening events or early death in future patients, especially in developing countries where availability of therapies such as cardioverter defibrillator are very limited, or require time for its funding. PMID:25882468

  15. Unusual oral findings in dermatosparaxis (Ehlers-Danlos syndrome type VIIC).

    PubMed

    De Coster, P J; Malfait, F; Martens, L C; De Paepe, A

    2003-10-01

    A 13-year-old patient with dermatosparaxis (Ehlers-Danlos syndrome type VIIC), an autosomal recessive disorder of procollagen-I-N-proteinase, is presented. The oral findings comprise micrognathia, hypodontia, localized microdontia, opalescent tooth discoloration, root dysplasia, pulp obliteration, severe gingival hyperplasia, frontal open bite, and severe restriction of TMJ mobility. The reported anomalies suggest the need for expanding the present phenotypic spectrum. This is the first report on oral findings in the syndrome. PMID:12969232

  16. Is intravenous contrast necessary for detection of clinically significant extracolonic findings in patients undergoing CT colonography?

    PubMed Central

    Alkandari, LAA; Haaland, B; Low, W; Tan, C H

    2014-01-01

    Objective: To determine whether intravenous contrast (IVC) is necessary for detection of extracolonic findings (ECFs) in patients undergoing CT colonography (CTC). Methods: We performed a retrospective review of CT findings in 179 cases of CTC studies performed over 18 months where both pre-contrast (NECT) and post-contrast (CECT) scans were performed in the prone and supine positions, respectively, in the same patients. All ECFs were recorded on a per patient basis and graded according to the colonography reporting and data system classification. Results: There was no significant change in E grade for the cohort (p?=?0.171) between the NECT and CECT scans. On the CECT scans, additional findings were detected in 49.1% of patients. Overall, there were 27/179 (15.1%) patients graded E3 and 18/179 (10.1%) patients graded E4 on the CECT study. Compared with the NECT study, there was a decrease of 12.9% of patients graded E3 and no change in the number of patients graded E4. Conclusion: With IVC administration, additional ECFs are detected in nearly half of all patients. However, there was no increase in the number of patients with clinically significant lesions. The risk–benefit ratio of routine IVC administration for CTC in symptomatic patients thus requires further evaluation. Advances in knowledge: This study reviews the utility of IVC in CTC and is thus relevant to current clinical practice at many institutions. PMID:24625066

  17. Variable CT Findings of Epithelial Origin Ovarian Carcinoma According to the Degree of Histologic Differentiation

    PubMed Central

    Jang, Yun-Jin; Park, Sung Bin; Cho, Kyoung-Sik

    2007-01-01

    Objective We wanted to evaluate the CT findings of epithelial origin ovarian carcinoma according to the degree of histologic differentiation. Materials and Methods This study enrolled 124 patients with 31 well differentiated, 44 moderately differentiated and 95 poorly differentiated carcinomas with epithelial origin. The CT images were retrospectively evaluated with regard to bilateral ovarian involvement, the tumor's nature, lymphadenopathy, adjacent organ invasion, peritoneal tumor seeding, a large amount of ascites and distant metastasis. In cystic, predominantly cystic and mixed tumors, the tumor wall, septa, papillary projection and necrosis in the solid portion were assessed. Results Bilateral ovarian involvement was more common in the poorly (48%) and moderately (42%) differentiated carcinomas than in the well differentiated carcinomas (7%) (p < 0.05). The frequency of a predominantly solid or solid nature was greater in the moderately and poorly differentiated carcinomas than in the well differentiated carcinomas (p < 0.0001). In the 87 tumors with a cystic, predominantly cystic or mixed nature, septa greater than 3 mm, papillary projection and necrosis in the solid portion were more common in the poorly differentiated carcinoma (91%, 91% and 77%, respectively) than in the moderately (64%, 68% and 34%, respectively) and well differentiated carcinomas (63%, 47% and 27%, respectively) (p < 0.05). Lymphadenopathy, organ invasion, tumor seeding and a large amount of ascites were more common in the poorly differentiated carcinomas (38%, 27%, 73% and 69%, respectively) than in the moderately (13%, 10%, 48% and 45%, respectively) and well differentiated carcinomas (3%, 0%, 10% and 17%, respectively) (p < 0.05). Conclusion Epithelial origin ovarian carcinoma shows different CT findings according to the degree of histologic differentiation. PMID:17420629

  18. Bilateral alien hand syndrome in cerebrovascular disease: CT, MR, CT angiography, and 99mTc-HMPAO-SPECT findings.

    PubMed

    Serrano-Vicente, Justo; Duran-Barquero, Carmen; Garcia-Bernardo, Lucia; Dominguez-Grande, Maria Luz; Infante-Torre, Jose Rafael; Rayo-Madrid, Juan Ignacio

    2015-03-01

    We report a 65-year-old man with a right cerebral infarction that occurred 15 years ago and a residual left hemiparesis that began with progressive contralateral hemiparesis. During the hospitalization, the patient developed a bilateral alien hand syndrome. Urgent CT, MR, CT angiography, and brain perfusion SPECT were performed that revealed an old right cerebral infarction and a new ischemic lesion in left parietal lobe and adjacent brain territories. PMID:25546190

  19. Gorlin-Goltz syndrome: incidental finding on routine ct scan following car accident

    PubMed Central

    2009-01-01

    Introduction Gorlin-Goltz syndrome is a rare hereditary disease. Pathogenesis of the syndrome is attributed to abnormalities in the long arm of chromosome 9 (q22.3-q31) and loss or mutations of human patched gene (PTCH1 gene). Multiple basal cell carcinomas (BCCs), odontogenic keratocysts, skeletal abnormalities, hyperkeratosis of palms and soles, intracranial ectopic calcifications of the falx cerebri and facial dysmorphism are considered the main clinical features. Diagnosis is based upon established major and minor clinical and radiological criteria and ideally confirmed by DNA analysis. Because of the different systems affected, a multidisciplinary approach team of various experts is required for a successful management. Case presentation We report the case of a 19 year-old female who was involved in a car accident and found to present imaging findings of Gorlin-Goltz syndrome during a routine whole body computed tomography (CT) scan in order to exclude traumatic injuries. Conclusion Radiologic findings of the syndrome are easily identifiable on CT scans and may prompt to early verification of the disease, which is very important for regular follow-up and better survival rates from the co-existent diseases. PMID:20062724

  20. Tuberculous spondylodiscitis in a patient with a sickle-cell disease: CT findings

    PubMed Central

    Krupniewski, Leszek; Palczewski, Piotr; Go??biowski, Marek; Kosi?ska-Kaczy?ska, Katarzyna

    2012-01-01

    Summary Background: Although sickle-cell anemia (SCA) is common in black Americans, Sub-Saharan Africa and in the Mediterranean area, the disease is rare in the temperate climate zone. The manifestations of the disease are related mainly to the production of abnormal hemoglobin that leads to organ ischemia and increased susceptibility to infection caused by functional asplenia. Case Report: The authors present CT findings in a 39-year-old black woman diagnosed due to abdominal pain, lymphadenopathy and fever. CT of the thorax and abdomen demonstrated changes in the liver, spleen, and skeletal system suggestive of SCA complicated with spondylodiscitis in the thoracic spine. Discussion: Hepatomegaly and small calcified spleen are typical findings in older homozygotic patients with SCA. The lesions in the skeleton may be related either to intramedullary hematopoiesis or osteonecrosis and osteomyelitis. In the latter case, diffuse osteosclerosis and H-shaped vertebrae are most typical. Tuberculous spondylodiscitis is characterized by the location in the thoracic region, preferential involvement of anterior elements, relative sparing of intervertebral discs, and cold abscesses. PMID:22802871

  1. Unusual Malignant Solid Neoplasms of the Kidney: Cross-Sectional Imaging Findings

    PubMed Central

    Karaosmano?lu, Ali Devrim; Shirkhoda, Ali; Ozmen, Mustafa; Hahn, Peter F.

    2015-01-01

    Malignant kidney neoplasms are the most frequently encountered solid kidney masses. Although renal cell carcinoma is the major renal malignancy, other solid malignant renal masses should be considered in the differential diagnosis of solid renal masses that do not contain a macroscopic fatty component. In this pictorial essay, we present the imaging findings of a primitive neuroectodermal tumor, primary liposarcoma of the kidney, primary neuroendocrine tumor, leiomyosarcoma, synovial sarcoma, malignant fibrous histiocytoma, sclerosing fibrosarcoma and renal metastasis of osteosarcoma.

  2. Uncommon CT imaging of the hepatic falciform artery in patients presenting with very unusual variants of gastrointestinal arteries: report of two cases.

    PubMed

    Coulier, Bruno

    2015-07-01

    The hepatic falciform artery (HFA) may be found in 68 % of subjects in post-mortem dissections. It is well known by interventional radiologists who perform selective hepatic angiography. The reason essentially results from the potential supraumbilical skin complications which may produce by the distribution of chemotherapeutic agents through the HFA after transcatheter chemoinfusion or chemoembolization for liver tumors. Nevertheless, the spontaneous visualization of the HFA remains very unusual in current abdominal CT practice. We hereby report the demonstration of a patent HFA during conventional abdominal CT in two patients presenting without liver disease but in which very unusual variants of the gastrointestinal arteries were simultaneously found. The first patient had a common celiomesenteric trunk and the second had a severe compression of both the celiac trunk and superior mesenteric artery by the median arcuate ligament of the diaphragm. We shortly review the literature about these rare variants. We hypothesize that the HFA was spontaneously visible in our patients because of hypertrophy due supplying collateralization. PMID:25791132

  3. Early Head CT Findings Are Associated With Outcomes After Pediatric Out-of-Hospital Cardiac Arrest

    PubMed Central

    Starling, Rebecca M.; Shekdar, Karuna; Licht, Dan; Nadkarni, Vinay M.; Berg, Robert A.; Topjian, Alexis A.

    2015-01-01

    Objectives Head CT after out-of-hospital cardiac arrest is often obtained to evaluate intracranial pathology. Among children admitted to the PICU following pediatric out-of-hospital cardiac arrest, we hypothesized that loss of gray-white matter differentiation and basilar cistern and sulcal effacement are associated with mortality and unfavorable neurologic outcome. Design Retrospective, cohort study. Setting Single, tertiary-care center PICU. Patients Seventy-eight patients less than 18 years old who survived out-of-hospital cardiac arrest to PICU admission and had a head CT within 24 hours of return of spontaneous circulation were evaluated from July 2005 through May 2012. Interventions None. Measurements and Main Results Median time to head CT from return of spontaneous circulation was 3.3 hours (1.0, 6.0). Median patient age was 2.3 years (0.4, 9.5). Thirty-nine patients (50%) survived, of whom 29 (74%) had favorable neurologic outcome. Nonsurvivors were more likely than survivors to have 1) loss of gray-white matter differentiation (Hounsfield unit ratios, 0.96 [0.88, 1.07] vs 1.1 [1.07, 1.2]; p < 0.001), 2) basilar cistern effacement (93% vs 7%; p = 0.001; positive predictive value, 94%; negative predictive value, 59%), and 3) sulcal effacement (100% vs 0%; p ? 0.001; positive predictive value, 100%; negative predictive value, 68%). All patients with poor gray-white matter differentiation or sulcal effacement had unfavorable neurologic outcomes. Only one patient with basilar cistern effacement had favorable outcome. Conclusions Loss of gray-white matter differentiation and basilar cistern effacement and sulcal effacement are associated with poor outcome after pediatric out-of-hospital cardiac arrest. Select patients may have favorable outcomes despite these findings. PMID:25844694

  4. [CT findings and surgical treatment of atlanto-axial rotatory fixation: a case report].

    PubMed

    Shoji, A; Nakagawa, H; Harano, H; Okumura, T; Sugiyama, T

    1984-07-01

    A case of atlanto-axial rotatory fixation (AARF) was presented in a 19-year-old female who developed sudden onset of neck pain and limitation of neck movement after direct carotid angiography for seizure disorder. Neurological examination was negative except for cock-robin posture and mild hypesthesia and hypalgesia in left C2 distribution. Plain films of the cervical spine disclosed abnormal alignment of C1-C2 and possible rotational dislocation. Bilateral selective vertebral angiography showed marked anterior and posterior displacement of left and right vertebral artery, respectively, at the level of C1. On CT metrizamide myelography, there was clockwise rotation of C1 on C2 with locked facet on the left but no evidence of cord compression was found. With diagnosis of AARF, manual reduction under general anesthesia and with fluoroscopic control was first attempted without success. Therefore, the patient underwent open reduction by using high speed air-drill and posterior fusion of C1 to C3 with acryl and wire. Postoperative course was uneventful and the patient went back to work as a computer operator in three months. The etiology of AARF was described by many authors, but in our case, congenital hypogenesis of transverse and alar ligaments plus minor trauma was most suggested. For neurological manifestations of AARF, occipital neuralgia, headache, neck pain, limitation of neck movement and cock-robin posture were reported, but the cock-robin posture was most characteristic and was an important symptom for the early diagnosis. In neuroradiological findings of AARF, plain CT and CT metrizamide myelography are very useful. Because they clearly demonstrate the degree of rotation and interlocking of atlanto-axial joints, and the presence of cord compression. PMID:6483106

  5. A rare syndrome with unusual dental findings: Oculo-facio-cardio-dental syndrome

    PubMed Central

    Verma, Geeta; Singh, Gulshan Kumar; Tandon, Pradeep; Verma, Sneh Late

    2014-01-01

    Radiculomegaly of a tooth is a rare condition. When it is associated with other dental abnormalities, facial dysmorphism and congenital cataracts, the condition is named as oculofaciocardiodental (OFCD) syndrome. This is an X-linked dominant trait, reported only in women, suggesting that it is lethal in males. The most consistent and pathognomic dental finding of OFCD is radiculomegaly (extremely long roots), particularly of the canines and occasionally of other teeth including premolars and incisors, which can easily be diagnosed on dental panoramic radiographs by a dentist or an orthodontist. Till date, 21 cases have been reported worldwide. The aim of this report is to present a new case of a 24 year old female affected by this syndrome and to evaluate it from a dental perspective to call the attention of dentists to this rare anomaly. PMID:25328326

  6. Unusual Larva in the CSF and Unique MRI Findings in a Case of Eosinophilic Meningitis

    PubMed Central

    Rai, Santosh; Madi, Deepak; Pai, Shivanand; Baliga, Shrikala

    2014-01-01

    Eosinophilic meningitis may be caused by non-infectious and infectious agents. Angiostrongylus cantonensis is the commonest causative agent of eosinophilic meningitis. Rats are the primary hosts of this parasite. Humans get infected by ingestion of raw or inadequately cooked hosts (snails or monitor lizard) or food contaminated with the infective third-stage larvae. A 16-year-old boy was admitted to our hospital with history of fever, headache, and altered sensorium. Magnetic resonance imaging of the brain showed unique findings. Cerebrospinal fluid (CSF) examination showed eosinophilia and the CSF wet mount identified a larva. Patient history revealed ingestion of monitor lizard 2 weeks prior to onset of symptoms. Hence, a diagnosis of eosinophilic meningitis caused by A. cantonensis was made. He was treated with oral albendazole and steroids, resulting in gradual improvement. A. cantonensis as a cause of eosinophilic meningitis is a possibility in patients who present with headache and vomiting after eating raw meat (monitor lizard). To the best of our knowledge, this is a very rare case being reported from India where the larva was identified during the microscopic examination of the CSF. PMID:25806134

  7. Fluorine18FDG PET findings of focal eosinophilic liver disease: correlation with CT and\\/or MRI, laboratory, and pathologic findings

    Microsoft Academic Search

    Won Hwa Kim; Se Hyung Kim; Young Hoon Kim; Sun Ho Youn; Won Jun Kang; Min A. Kim; Joon Koo Han; Byung Ihn Choi

    2010-01-01

    Purpose  To review the 2-deoxy-2-fluoro-[F-18]-d-glucose (FDG) positron emission tomography (PET) findings of focal eosinophilic liver disease (FELD) and to correlate them\\u000a with radiologic and pathologic findings.\\u000a \\u000a \\u000a \\u000a \\u000a Materials and methods  Fourteen patients, who were clinically or pathologically diagnosed as FELD and underwent CT and\\/or MR and PET, were enrolled.\\u000a Two radiologists analyzed CT and MRI regarding size, shape, margin, attenuation, signal intensity (SI),

  8. Fluorine18FDG PET findings of focal eosinophilic liver disease: correlation with CT and\\/or MRI, laboratory, and pathologic findings

    Microsoft Academic Search

    Won Hwa Kim; Se Hyung Kim; Young Hoon Kim; Sun Ho Youn; Won Jun Kang; Min A. Kim; Joon Koo Han; Byung Ihn Choi

    Purpose  To review the FDG–PET findings of focal eosinophilic liver disease (FELD) and to correlate them with radiological and pathological\\u000a findings.\\u000a \\u000a \\u000a \\u000a Materials and methods  Fourteen patients who were clinically or pathologically diagnosed as FELD and underwent CT and\\/or MR and positron emission\\u000a tomography (PET) were enrolled. Two radiologists analyzed CT and MRI regarding size, shape, margin, attenuation, signal intensity\\u000a (SI), and enhancement

  9. CT and MRI findings of renal infestation by a huge active hydatid cyst

    PubMed Central

    Kizildag, Betul; Dagistan, Emine; Gurel, Safiye; Alan, Cabir

    2013-01-01

    Hydatid cysts derived from a type of tapeworm called Echinococcus granulosis larvaes which can situate in various organs or tissues in human body. It encounters as an endemic zoonosis in many regions all over the world including eastern part of Turkey. Renal involvement of hydatid cysts is uncommon even in endemic areas. The imaging properties vary according to the phase of the disease. Although it is a benign condition, the diagnosis of a renal hydatid cyst is critical in managing treatment and complications, such as nephrectomy, medical treatment before surgery and the risk of anaphylaxis or dissemination during intervention. Herein authors reported a case of an isolated involvement of the right kidney by a huge active hydatid cyst in a young man who was treated surgically, emphasising its ultrasound, CT, contrast-enhanced MR and diffusion-weighted imaging findings. PMID:23833098

  10. CT detection of facial canal dehiscence and semicircular canal fistula: Comparison with surgical findings

    SciTech Connect

    Fuse, Takeo; Tada, Yuichiro; Aoyagi, Masaru; Sugai, Yukio [Yamagata Univ. School of Medicine (Japan)] [Yamagata Univ. School of Medicine (Japan)

    1996-03-01

    The purpose of this study was to determine the accuracy of high resolution CT (HRCT) in the detection of facial canal dehiscence and semicircular canal fistula, the preoperative evaluation of both of which is clinically very important for ear surgery. We retrospectively reviewed the HRCT findings in 61 patients who underwent mastoidectomy at Yamagata University between 1989 and 1993. The HRCT images were obtained in the axial and semicoronal planes using 1 mm slice thickness and 1 mm intersection gap. In 46 (75%) of the 61 patients, the HRCT image-based assessment of the facial canal dehiscence coincided with the surgical findings. The data for the facial canal revealed sensitivity of 66% and specificity of 84%. For semicircular canal fistula. in 59 (97%) of the 61 patients, the HRCT image-based assessment and the surgical findings coincided. The image-based assessment in the remaining two patients, who both had massive cholesteatoma, was false-positive. HRCT is useful in the diagnosis of facial canal dehiscence and labyrinthine fistula, but its limitations should also be recognized. 12 refs., 3 figs., 6 tabs.

  11. Radiologists' performance in the diagnosis of acute intestinal ischemia, using MDCT and specific CT findings, using a variety of CT protocols.

    PubMed

    Blachar, Arye; Barnes, Sophie; Adam, Sharon Z; Levy, Gad; Weinstein, Iuliana; Precel, Ronit; Federle, Michael P; Sosna, Jacob

    2011-10-01

    The aim of this study was to evaluate the performance of radiologists in the diagnosis of acute intestinal ischemia using specific multi-detector CT findings. The abdominal CT scans of 90 patients were retrospectively reviewed by three radiologists: an abdominal imaging specialist, an experienced general radiologist, and a senior resident. Forty-seven patients had surgically proven intestinal ischemia and comprised the case group, while 43 patients had no evidence of intestinal ischemia at surgery and comprised the control group. Images were reviewed in a random and blinded fashion. Radiologists' performance in diagnosing bowel ischemia from other bowel pathologies was evaluated. The sensitivity, specificity, and accuracy for diagnosing bowel ischemia were 89%, 67%, and 79% for the abdominal imager; 83%, 67%, and 76% for the general radiologist; and 66%, 83%, and 74% for the senior resident, respectively. The calculated kappa value for inter-observer agreement regarding the presence of bowel ischemia was 0.79. CT findings that significantly distinguished bowel ischemia from other bowel pathologies were decreased or absent bowel wall enhancement, filling defect in the superior mesenteric artery, small bowel pneumatosis, and gas in the portal veins or superior mesenteric vein. For most of these signs, there was good inter-observer agreement. Radiologists' performance in diagnosing bowel ischemia is good, but lower than previously reported since a significant amount of cases are evaluated using a suboptimal CT technique. Radiologists' experience and expertise have an important impact on their performance. PMID:21655965

  12. Value of CT angiography in anterior circulation large vessel occlusive stroke: Imaging findings, pearls, and pitfalls.

    PubMed

    Power, Sarah; McEvoy, Sinead H; Cunningham, Jane; Ti, Joanna P; Looby, Seamus; O'Hare, Alan; Williams, David; Brennan, Paul; Thornton, John

    2015-07-01

    Hyperacute stroke imaging is playing an increasingly important role in determining management decisions in acute stroke patients, particularly patients with large vessel occlusive stroke who may benefit from endovascular intervention. CT angiography (CTA) is an important tool in the work-up of the acute stroke patient. It reliably detects large occlusive thrombi in proximal cerebral arteries and is a quick and highly accurate method in identifying candidates for endovascular stroke treatment. In this article we review the imaging findings on CTA in acute large vessel occlusive stroke using a pictorial case based approach. We retrospectively reviewed CTA studies in 48 patients presenting with acute anterior circulation large vessel occlusive stroke who were brought for intra-arterial acute stroke intervention. We discuss and illustrate patterns of proximal intracranial arterial occlusion, collateralization to the occluded territory, as well as reviewing some important pearls, pitfalls and teaching points in CTA assessment of the acute stroke patient. Performed from the level of the aortic arch CTA also gives valuable information regarding the state of other vessels in the acute stroke patient, identifying additional significant vascular stenoses or occlusions, and as we illustrate, can demonstrate other clinically significant findings which may impact on patient management and outcome. PMID:25956493

  13. Hepatocellular carcinoma: reduced frequency of typical findings with dynamic contrast-enhanced CT in a non-Asian population.

    PubMed

    Freeny, P C; Baron, R L; Teefey, S A

    1992-01-01

    Four computed tomographic (CT) findings have been described as typical or diagnostic of hepatocellular carcinoma: Primary morphologic findings include tumor encapsulation and fatty metamorphosis and secondary findings include venous invasion and arterioportal shunting. However, virtually all of the articles reporting these findings with significant frequency have been from Japan and thus represent an almost purely Asian population. The authors analyzed a series of 93 patients with hepatocellular carcinoma, only eight of whom were Asian. With the exception of venous invasion (48%), the analysis showed that while the four CT features may be typical of hepatocellular carcinoma, three features occurred with low frequency in a non-Asian population: tumor encapsulation, 12%; fatty metamorphosis, 0%; and arterioportal shunting, 4%. In addition, a review of the literature showed that all of the findings have occurred in other hepatic neoplasms, including benign and metastatic tumors. PMID:1309214

  14. CT Findings in Bronchiectasis: Limited Value in Distinguishing Between Idiopathic and Specific Types

    Microsoft Academic Search

    Daniel B. Reiff; Athol U. Wells; Denis H. Carr; Peter J. Cole; David M. Hansell

    OBJECTIVE. The purpose of this study was to determine whether the pattern and distribution of bronchiectasis shown on CT scans can be used to discriminate between idiopathic cases and those with an identifiable cause. MATERIALS AND METHODS. The CT scans of 168 patients with chronic purulent sputum production and who were suspected of having bronchiectasis were analyzed (117 patients with

  15. Automated Quantification of High-Resolution CT Scan Findings in Individuals at Risk for Pulmonary Fibrosis

    PubMed Central

    Rosas, Ivan O.; Yao, Jianhua; Avila, Nilo A.; Chow, Catherine K.; Gahl, William A.

    2011-01-01

    Background: Automated methods to quantify interstitial lung disease (ILD) on high-resolution CT (HRCT) scans in people at risk for pulmonary fibrosis have not been developed and validated. Methods: Cohorts with familial pulmonary fibrosis (n = 126) or rheumatoid arthritis with and without ILD (n = 86) were used to develop and validate a computer program capable of quantifying ILD on HRCT scans, which imaged the lungs semicontinuously from the apices to the lung bases during end-inspiration in the prone position. This method uses segmentation, texture analysis, training, classification, and grading to score ILD. Results: Quantification of HRCT scan findings of ILD using an automated computer program correlated with radiologist readings and detected disease of varying severity in a derivation cohort with familial pulmonary fibrosis or their first-degree relatives. This algorithm was validated in an independent cohort of subjects with rheumatoid arthritis with and without ILD. Automated classification of HRCT scans as normal or ILD was significant in the derivation and validation cohorts (P < .001 and P < .001, respectively). Areas under receiver operating characteristic curves performed independently for each group were 0.888 for the derivation cohort and 0.885 for the validation cohort. Pulmonary function test results, including FVC and diffusion capacity, correlated with computer-generated HRCT scan scores for ILD (r = ?0.483 and r = ?0.532, respectively). Conclusions: Automated computer scoring of HRCT scans can objectively identify ILD and potentially quantify radiographic severity of lung disease in populations at risk for pulmonary fibrosis. PMID:21622544

  16. Burkitt's Lymphoma Presented as Advanced Ovarian Cancer without Evidence of Lymphadenopathy: CT and MRI Findings

    PubMed Central

    Manganaro, Lucia; Bernardo, Silvia; Sergi, Maria Eleonora; Sollazzo, Paolo; Vinci, Valeria; De Grazia, Alessandra; Clerico, Anna; Mollace, Maria Giovanna; Saldari, Matteo

    2013-01-01

    Burkitt's lymphoma is a rare non-Hodgkin's lymphoma which can occasionally involve the ovary and may cause confusion for the clinician since its presentation might mimic other much more frequent tumors. We present a case of a 23-year-old woman with sporadic Burkitt's lymphoma presented as advanced ovarian cancer with bilateral ovarian masses, peritoneal carcinomatosis, ascites, and marked elevation of CA-125. Liver involvement and atypical bone lesions, such as the cranial vault and the iliac wing, were also detected without evidence of lymphadenopathy. We describe the MRI and CT findings of simultaneous ovarian and bone lesions, which have never been reported in literature in a patient with Burkitt's lymphoma, before and after one cycle of chemotherapy. In evaluating any ovarian neoplasm in a young woman, Burkitt's lymphoma should be considered as a possibility, particularly if associated with bone lesions. MRI is the most useful tool to characterize the ovarian lesions and suggest the diagnosis before the histopathological results. PMID:23607034

  17. Bilateral adrenal cystic lymphangiomas in nevoid basal cell carcinoma (Gorlin-Goltz) syndrome: US, CT, and MR findings.

    PubMed

    Mortelé, K J; Hoier, M R; Mergo, P J; Ros, P R

    1999-01-01

    We present a case of bilateral adrenal cystic lymphangioma in a patient with the Gorlin-Goltz syndrome. This case is unique as it is the first illustrated case (US, CT, and MR findings) of a cystic lymphangioma arising within the adrenal gland. In addition, the coexistence of cystic adrenal lymphangioma with the Gorlin-Goltz syndrome has not been described previously. PMID:10433287

  18. NIH study finds childhood CT scans linked to leukemia and brain cancer later in life

    Cancer.gov

    Children and young adults scanned multiple times by computed tomography (CT), a commonly used diagnostic tool, have a small increased risk of leukemia and brain tumors in the decade following their first scan.

  19. Myoepitheliomas of the Soft Palate: Helical CT Findings in Two Patients

    PubMed Central

    Lee, Won Mi; Choi, Sun Myung

    2007-01-01

    We describe the enhancement patterns of myoepithelioma in two patients with a soft palate mass. In the first case, helical CT revealed a faintly enhancing mass. Histologically, the tumor was composed of plasmacytoid cells in a background of rich myxoid stroma. Immunostaining for CD34 showed scanty blood vessels. In the second case, helical CT revealed an intensely enhancing mass. Histologically, the mass was a cellular tumor with fibrous stroma. Immunostaining for CD34 also showed frequent blood vessels. PMID:18071288

  20. Misty mesentery: a pictorial review of multidetector-row CT findings

    Microsoft Academic Search

    A. Filippone; R. Cianci; F. Di Fabio; M. L. Storto

    2011-01-01

    The term “misty mesentery” indicates a pathological increase in mesenteric fat attenuation at computed tomography (CT). It\\u000a is frequently observed on multidetector CT (MDCT) scans performed during daily clinical practice and may be caused by various\\u000a pathological conditions, including oedema, inflammation, haemorrhage, neoplastic infiltration or sclerosing mesenteritis.\\u000a In patients suffering from acute abdominal disease, misty mesentery may be considered a

  1. UNUSUAL FINDINGS IN ZEBRAFISH, DANIO RERIO, FROM TOXICOLOGICAL STUDIES AND THE ZEBRAFISH INTERNATIONAL RESOURCE CENTER DIAGNOSTIC SERVICE

    EPA Science Inventory

    A number of interesting and unusual lesions have been diagnosed in zebrafish that have been evaluated from toxicological studies or submitted as cases to the Diagnostic Service at Oregon State University. Lesions were observed in various wild-type and mutant lines of zebrafish an...

  2. Fat Necrosis of the Breast: A Pictorial Review of the Mammographic, Ultrasound, CT, and MRI Findings with Histopathologic Correlation

    PubMed Central

    Kerridge, William D.; Kryvenko, Oleksandr N.; Thompson, Afua; Shah, Biren A.

    2015-01-01

    Fat necrosis of the breast is a challenging diagnosis due to the various appearances on mammography, ultrasound, CT, PET-CT, and MRI. Although mammography is more specific, ultrasound is a very important tool in making the diagnosis of fat necrosis. MRI has a wide spectrum of findings for fat necrosis and the appearance is the result of the amount of the inflammatory reaction, the amount of liquefied fat, and the degree of fibrosis. While CT and PET-CT are not first line imaging examinations for the diagnosis of breast cancer or fat necrosis, they are frequently performed in the surveillance and staging of disease. Knowledge of how fat necrosis presents on these additional imaging techniques is important to prevent misinterpretation of the imaging findings. Gross and microscopic appearances of fat necrosis depend on the age of the lesion; the histologic examination of fat necrosis is usually straightforward. Knowledge of the variable appearances of fat necrosis on a vast array of imaging modalities will enhance a radiologist's accuracy in the analysis and interpretation of fat necrosis versus other diagnoses. PMID:25861475

  3. CT appearance of splenosis

    SciTech Connect

    Mendelson, D.S.; Cohen, B.A.; Armas, R.R.

    1982-12-01

    Splenosis is an unusual complication of splenic trauma. The computed tomographic (CT) appearance of splenosis is described. One should consider this diagnosis when faced with a history of splenic trauma and multiple round or oval masses at CT.

  4. 18F-FDG PET/CT Findings in a Patient With a Proliferating Trichilemmal Cyst.

    PubMed

    Leyendecker, Pierre; de Cambourg, Ghislaine; Mahé, Antoine; Imperiale, Alessio; Blondet, Cyrille

    2015-07-01

    Proliferating trichilemmal cyst is considered as a rare tumor that originates in the outer root sheath of hair follicle. Metastatic potential has not been yet fully established. Moreover, histological analysis does not allow precise malignancy prediction. Proliferating trichilemmal cyst glucose metabolism behavior was never previously described. Herein, we report the case of a 62-year-old patient with a left shoulder proliferating trichilemmal cyst showing an intense uptake of F-FDG on PET/CT examination. F-FDG PET/CT could be proposed to optimize diagnostic strategy of patients with proliferating trichilemmal cysts. PMID:25706794

  5. Inflammatory breast cancer: PET\\/CT, MRI, mammography, and sonography findings

    Microsoft Academic Search

    Wei T. Yang; Huong T. Le-Petross; Homer Macapinlac; Selin Carkaci; Ana M. Gonzalez-Angulo; Shaheenah Dawood; Erika Resetkova; Gabriel N. Hortobagyi; Massimo Cristofanilli

    2008-01-01

    Purpose  To describe the role of Positron Emission Tomography\\/Computed Tomography (PET\\/CT), Magnetic Resonance Imaging (MRI), sonography,\\u000a and mammography in patients with inflammatory breast cancer (IBC).\\u000a \\u000a \\u000a \\u000a Materials and methods  Patients who had been newly diagnosed with IBC and who had undergone mammography, sonography, MRI, PET\\/CT, or a combination\\u000a of these were included in this study. The visibility of breast parenchymal lesion (BPLs), skin

  6. Ultrasound findings of incidental adnexal and ovarian lesions on emergency CT scans.

    PubMed

    Lin, Roger Chin; Maliyekkel, Anil Thomas; Paspulati, Raj Mohan

    2015-01-01

    A search through 6076 nontraumatic emergency computed tomography (CT) scans of female patients yielded 266 (4.4%) CT scans with an incidentally detected adnexal lesion and ultrasound follow-up within 7days. The population was 87% premenopausal and 13% postmenopausal. Follow-up ultrasound yielded an ultrasound diagnosis 32% of the time. Potentially serious diagnoses included pelvic infection (3%) and suspected malignancy (2%). Benign diagnoses included normal ovaries (16%), hemorrhagic cyst (6%), and benign cyst (5%). The remaining 68% of cases were equivocal, requiring further evaluation. PMID:25920533

  7. PET CT Thresholds for Radiotherapy Target Definition in Non-Small-Cell Lung Cancer: How Close are we to the Pathologic Findings?

    SciTech Connect

    Wu Kailiang [Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON (Canada); Department of Radiotherapy, Cancer Hospital, Fudan University, Shanghai (China); Ung, Yee C., E-mail: yee.ung@sunnybrook.c [Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON (Canada); Hornby, Jennifer [Department of Thoracic Surgery, University of Toronto, Toronto, ON (Canada)

    2010-07-01

    Purpose: Optimal target delineation threshold values for positron emission tomography (PET) and computed tomography (CT) radiotherapy planning is controversial. In this present study, different PET CT threshold values were used for target delineation and then compared pathologically. Methods and Materials: A total of 31 non-small-cell lung cancer patients underwent PET CT before surgery. The maximal diameter (MD) of the pathologic primary tumor was obtained. The CT-based gross tumor volumes (GTV{sub CT}) were delineated for CT window-level thresholds at 1,600 and -300 Hounsfield units (HU) (GTV{sub CT1}); 1,600 and -400 (GTV{sub CT2}); 1,600 and -450 HU (GTV{sub CT3}); 1,600 and -600 HU (GTV{sub CT4}); 1,200 and -700 HU (GTV{sub CT5}); 900 and -450 HU (GTV{sub CT6}); and 700 and -450 HU (GTV{sub CT7}). The PET-based GTVs (GTV{sub PET}) were autocontoured at 20% (GTV{sub 20}), 30% (GTV{sub 30}), 40% (GTV{sub 40}), 45% (GTV{sub 45}), 50% (GTV{sub 50}), and 55% (GTV{sub 55}) of the maximal intensity level. The MD of each image-based GTV in three-dimensional orientation was determined. The MD of the GTV{sub PET} and GTV{sub CT} were compared with the pathologically determined MD. Results: The median MD of the GTV{sub CT} changed from 2.89 (GTV{sub CT2}) to 4.46 (GTV{sub CT7}) as the CT thresholds were varied. The correlation coefficient of the GTV{sub CT} compared with the pathologically determined MD ranged from 0.76 to 0.87. The correlation coefficient of the GTV{sub CT1} was the best (r = 0.87). The median MD of GTV{sub PET} changed from 5.72cm to 2.67cm as the PET thresholds increased. The correlation coefficient of the GTV{sub PET} compared with the pathologic finding ranged from 0.51 to 0.77. The correlation coefficient of GTV{sub 50} was the best (r = 0.77). Conclusion: Compared with the MD of GTV{sub PET}, the MD of GTV{sub CT} had better correlation with the pathologic MD. The GTV{sub CT1} and GTV{sub 50} had the best correlation with the pathologic results.

  8. Study Finds Small Increase in Cancer Risk after Childhood CT Scans

    Cancer.gov

    A study published in the June 6, 2012, issue of The Lancet shows that radiation exposure from computed tomography (CT) scans in childhood results in very small but increased risks of leukemia and brain tumors in the first decade after exposure.

  9. Non-Hodgkin lymphoma involving the parotid gland: CT and MR imaging findings

    PubMed Central

    Zhu, L; Wang, P; Yang, J; Yu, Q

    2013-01-01

    Objectives: As an uncommon neoplasm, parotid non-Hodgkin lymphoma (NHL) comprises mucosa-associated lymphoid tissue (MALT) and non-MALT lymphomas. Both types of lymphoma vary in prognosis and treatment. The aim of this study was to explore CT and MRI characteristics of these two types of lymphoma. Methods: 61 cases of parotid NHL, 34 MALT and 27 non-MALT lymphomas with histopathological confirmation were examined with routine CT and MR scans prior to treatment, and retrospectively reviewed. Results: On CT and MRI, 34 MALT lymphomas presented with 11 solid and 23 solid-cystic forms, whereas 27 non-MALT lymphomas presented with 25 solid and 2 solid-cystic forms (p?CT and MRI can offer helpful information for differentiation of both types of parotid NHL. PMID:23975113

  10. Rhinocerebral mucormycosis in a child with leukemia: CT and MRI findings

    Microsoft Academic Search

    P. Garces; D. Mueller; C. Trevenen

    1994-01-01

    A case of rhinocerebral mucormycosis in a child, evaluated by serial computed tomography (CT) and magnetic resonance imaging (MRI), is presented, demonstrating the severity and rapidity with which the infection extends from the paranasal sinuses to the orbits and ultimately to the brain.

  11. The Sturge-Weber syndrome: correlation between the clinical status and radiological CT and MRI findings

    Microsoft Academic Search

    L. Martí-Bonmatí; F. Menor; F. Mulas

    1993-01-01

    In the Sturge-Weber syndrome facial venous and leptomeningeal angiomas are associated. We studied 14 consecutive cases with clinical and radiological evaluations [computed tomography (CT) and magnetic resonance imaging (MRI)]. Radiological studies demonstrated the extent and patency of the leptomeningeal angiomatous malformation, the degree of parenchymal atrophy, the presumed ischemic changes affecting the gray and white matter, the presence and extent

  12. Intraosseous pneumatocysts of the ilium: findings on radiographs and CT scans

    SciTech Connect

    Ramirez, H.; Blatt, E.S.; Cable, H.F.; McComb, B.L.; Zornoza, J.; Hibri, N.S.

    1984-02-01

    CT scans demonstrated a localized collection of gas adjacent to a normal sacroiliac joint in 5 patients. In each case the lesion was sharply demarcated by a thin sclerotic rim. A benign bone cyst was confirmed histologically in 2 cases. The radiologist should be aware of this appearance so as to avoid invasive procedures based on a misdiagnosis of infection or neoplasm.

  13. Gastric volvulus associated with congenital diaphragmatic hernia, wandering spleen, and intrathoracic left kidney: CT findings

    Microsoft Academic Search

    G. Pelizzo; M. A. Lembo; A. Franchella; A. Giombi; F. D'Agostino; S. Sala

    2001-01-01

    We present an unusual case of gastric volvulus associated with wandering spleen, a delayed manifestation of congenital diaphragmatic\\u000a hernia and left intrathoracic kidney. Gastric volvulus should be considered in any infant with unexplained vomiting and left\\u000a diaphragmatic anomaly: in these patients, developmental disorders of the peritoneal visceral attachments of the left upper\\u000a abdomen may coexist. The absence of ligamentous connections

  14. 18F-fluorodeoxyglucose PET/CT findings of a solitary primary hepatic lymphoma: A case report

    PubMed Central

    Pan, Bo; Wang, Cun-Shi; Han, Jian-Kui; Zhan, Lin-Feng; Ni, Ming; Xu, Shi-Cheng

    2012-01-01

    Primary hepatic lymphoma is extremely rare, and only a few cases have been described on positron emission tomography (PET) or PET/computed tomography (PET/CT) imaging in the English literature. We report a case of a 55-year-old woman who presented with low-grade fever and weight loss of three months. On CT scanning, a mass was identified which appeared to be a hypoattenuating lesion, on ultrasonographic imaging, the mass was hypoechoic, therefore, liver abscess or hepatic metastasis from a gastrointestinal primary was initially suspected. Tumor markers such as alpha-fetoprotein, carcinoembryonic antigen and carbohydrate antigen 19-9 were within normal limits. PET/CT demonstrated a large abnormal ring-like hypermetabolic focus in the right liver lobe. The lesion was resected and the histopathological findings were consistent with lymphoma. The patient was discharged two weeks after surgery and did not receive any further treatment. After 25 mo follow-up, she is in good health. 18F-fluorodeoxyglucose PET/CT is useful in confirming the diagnosis of primary hepatic lymphoma by demonstrating no other foci with high uptake in other parts of the body. PMID:23326154

  15. Lung ischaemia–reperfusion injury in a canine model: dual-energy CT findings with pathophysiological correlation

    PubMed Central

    Xu, K; Zhang, L J; Morelli, J; Krazinski, A W; Silverman, J R; Schoepf, U J; Lu, G M

    2014-01-01

    Objective: To evaluate dual-energy CT (DECT) findings of pulmonary ischaemic–reperfusion injury (PIRI) and its pathophysiological correlation in the canine model. Methods: A PIRI model was established in 11 canines, utilizing closed pectoral balloon occlusion. Two control canines were also included. For the PIRI model, the left pulmonary artery was occluded with a balloon, which was deflated and removed after 2?h. DECT was performed before, during occlusion and at 2, 3 and 4?h thereafter and was utilized to construct pulmonary perfusion maps. Immediately after the CT scan at the fourth hour post reperfusion, the canines were sacrificed, and lung specimens were harvested for pathological analysis. CT findings, pulmonary artery pressure and blood gas results were then analysed. Results: Data at every time point were available for 10 animals (experimental group, n?=?8; control group, n?=?2). Quantitative measurements from DECT pulmonary perfusion maps found iodine attenuation values of the left lung to be the lowest at 2?h post embolization and the highest at 1?h post reperfusion. In the contralateral lung, perfusion values also peaked at 1?h post reperfusion. Continuous hypoxia and acid–based disorders were observed during PIRI, and comprehensive analysis showed physiological changes to be worst at 3?h post reperfusion. Conclusion: DECT pulmonary perfusion mapping demonstrated pulmonary perfusion of the bilateral lungs to be the greatest at 1?h post reperfusion. These CT findings corresponded with pathophysiological changes. Advances in knowledge: DECT pulmonary perfusion mapping can be used to evaluate lung ischaemia–reperfusion injury. PMID:24611753

  16. Post-treatment PET-CT Findings may Predict the Prognosis of DLBCL with a Bulky Mass.

    PubMed

    Takasaki, Hirotaka; Yamamoto, Wataru; Ishii, Yoshimi; Takahashi, Hiroyuki; Watanabe, Reina; Harada, Taishi; Kawasaki, Rika; Hashimoto, Chizuko; Motomura, Shigeki; Tomita, Naoto; Ishigatsubo, Yoshiaki; Sakai, Rika

    2015-09-01

    We retrospectively analyzed the prognosis of patients with diffuse large B cell lymphoma (DLBCL) and a bulky mass at diagnosis. We retrospectively analyzed clinical data for 29 consecutive DLBCL patients with an initial bulky mass receiving R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) therapy from 2004 to 2011. Bulky disease was defined as a measurable tumor mass >10 cm in diameter or a mediastinal mass >1/3 of the chest diameter. Patients with primary mediastinal large B-cell lymphoma were excluded. The median age was 65 years (20-78 years) and the maximum tumor diameter was 11.5 cm (10.0-17.0 cm). Complete response and partial response were achieved in 14 patients each, while 1 patient had progressive disease. The 3-year overall survival (OS) rate and progression-free survival (PFS) rate were 66 and 56 %, respectively. Findings on post-treatment positron emission tomography-computed tomography (PET-CT) were significantly associated with OS (34 % for patients with abnormal uptake vs. 75 % for those without, P = 0.014), and were also associated with PFS (36 vs. 83 %, respectively, P < 0.001). Nine patients with a single site of abnormal uptake on PET-CT underwent radiotherapy and 5 of them subsequently relapsed. An initial bulky mass does not indicate a poor prognosis of DLBCL. However, the post-treatment PET-CT findings may have predictive value in DLBCL patients with a bulky mass. PMID:26085719

  17. Ruptured giant intrathoracic lipoblastoma in a 4-month-old infant: CT and MR findings

    Microsoft Academic Search

    Chung Hun Park; Kun-Il Kim; Young Tak Lim; Sung Woon Chung; Chang Hoon Lee

    2000-01-01

    Background. We describe a 4-month-old infant with a ruptured intrathoracic lipoblastoma arising from the parietal pleura and associated\\u000a with a pleural effusion.¶Objective. The clinical presentation was rapidly evolving respiratory distress. The chest radiograph showed a large mass and a pleural\\u000a effusion in the right thoracic cavity. CT demonstrated an inhomogeneous low-attenuation mass which was 7 cm in diameter and\\u000a which

  18. CT and MR in non-neonatal hypoxic–ischemic encephalopathy: radiological findings with pathophysiological correlations

    Microsoft Academic Search

    Leonardo Guilhermino Gutierrez; Àlex Rovira; Luiz Antonio Pezzi Portela; Claudia da Costa Leite; Leandro Tavares Lucato

    2010-01-01

    Non-neonatal hypoxic–ischemic encephalopathy is a clinical condition often related to cardiopulmonary arrest that demands\\u000a critical management and treatment decisions. Management depends mainly on the degree of neurological impairment and prognostic\\u000a considerations. Computed tomography (CT) is often used to exclude associated or mimicking pathology. If any, only nonspecific\\u000a signs such as cerebral edema, sulci effacement, and decreased gray matter (GM)\\/white matter

  19. Focused radiation hepatitis after Bragg-peak proton therapy for hepatocellular carcinoma: CT findings

    SciTech Connect

    Okumura, Toshiyuki; Itai, Yuji; Tsuji, Hiroshi [Central Hospital of Ibaraki (Japan)] [and others

    1994-09-01

    Radiation hepatitis is clearly demonstrated by noncontrast and contrast enhanced CT following radiotherapy for liver diseases. Radiation hepatitis is dependent on dose distribution and is usually demonstrated as nonsegmental bandlike lesion after photon therapy. We report a case of focused, oval-shaped radiation hepatitis that was induced by photon therapy. The attenuation difference was localized in a high-dose area caused by Bragg-peak proton therapy. 17 refs., 2 figs.

  20. Multiphase helical CT findings after percutaneous ablation procedures for hepatocellular carcinoma

    Microsoft Academic Search

    O. Catalano; M. Esposito; A. Nunziata; A. Siani

    2000-01-01

    Background: Multiple-phase helical computed tomography (CT) has been regarded as the method of choice in the evaluation of patients with\\u000a hepatocellular carcinoma (HCC) treated by nonsurgical procedures. The aim of this article was to report our experience in\\u000a the assessment of nodular and parenchymal changes recognizable after various percutaneous ablation therapies.\\u000a \\u000a \\u000a \\u000a \\u000a Methods: We reviewed the studies of 116 consecutive patients

  1. Clinical significance of the finding of subarachnoid blood on CT scan after head injury.

    PubMed

    Kakarieka, A; Braakman, R; Schakel, E H

    1994-01-01

    The population analysed consisted of 268 out of 819 patients of a European nimodipine multicentre trial on severe head injury, whose first CT scan after injury showed signs of subarachnoid bleeding. The study demonstrated the importance of traumatic subarachnoid haemorrhage (tSAH) per se as a prognostic factor. The outcome of patients with tSAH is significantly worse than that of patients whose first CT does not show subarachnoid blood (noSAH). The outcome was unfavourable (dead, persistent vegetative state, severe disability) in 60% of tSAH patients compared to 30% of noSAH patients (p < 0.001). The difference in mortality was 42% vs. 14% (p < 0.001). The six month follow-up of tSAH patients complying with the study protocol and treated with intravenous nimodipine, 2 mg per hour for 7 days, showed a statistically significant reduction of unfavourable outcome from 66% to 51% (p < 0.05), compared to placebo treated patients. PMID:7998486

  2. MRI and FDG PET/CT findings in a case of probable Heidenhain variant Creutzfeldt-Jakob disease.

    PubMed

    Clarençon, F; Gutman, F; Giannesini, C; Pénicaud, A; Galanaud, D; Kerrou, K; Marro, B; Talbot, J-N

    2008-10-01

    Creutzfeldt-Jakob disease (CJD) is a neurodegenerative disease caused by the accumulation of a pathogenic isoform of a prion protein in neurons that is responsible for subacute dementia. The Heidenhain variant is an atypical form of CJD in which visual signs are predominant. This is a report of the case of a 65-year-old man with probable CJD of the Heidenhain variant, with topographical concordance between findings on magnetic resonance imaging (MRI) and 18F-fluorodeoxyglucose (FDG) photopenic areas on positron emission tomography (PET)/computed tomography (CT) for cortical parietooccipital lesions. PMID:18466976

  3. The impact of image fusion in resolving discrepant findings between FDG-PET and MRI\\/CT in patients with gynaecological cancers

    Microsoft Academic Search

    Cheng-Chien Tsai; Chien-Sheng Tsai; Koon-Kwan Ng; Chyong-Huey Lai; Swei Hsueh; Pan-Fu Kao; Ting-Chang Chang; Ji-Hong Hong; Tzu-Chen Yen

    2003-01-01

    This study was performed to prospectively investigate the impact of image fusion in resolving discrepant findings between fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and magnetic resonance imaging (MRI) or X-ray computed tomography (CT) in patients with gynaecological cancers. Discrepant findings were defined as lesions where the difference between the FDG-PET and MRI\\/CT images was assigned a value of at least

  4. Respiratory Symptoms in Rheumatoid Arthritis: Relation between High Resolution CT Findings and Functional Impairment

    Microsoft Academic Search

    Hiroshi Terasaki; Kiminori Fujimoto; Naofumi Hayabuchi; Yoshio Ogoh; Takaaki Fukuda; Nestor L. Müller

    Purpose: The objectives of this study were to analyze the high resolution computed tomography (HRCT) findings in rheumatoid arthritis (RA) patients with respiratory symptoms and to evaluate the relation between the extent of HRCT findings and functional impairment as assessed by spirometry. Materials and Methods: HRCT examination of the thorax and pulmonary function tests (PFTs) were performed in 34 RA

  5. Multi-detector CT assessment in pulmonary hypertension: techniques, systematic approach to interpretation and key findings.

    PubMed

    Lewis, Gareth; Hoey, Edward T D; Reynolds, John H; Ganeshan, Arul; Ment, Jerome

    2015-06-01

    Pulmonary arterial hypertension (PAH) may be suspected based on the clinical history, physical examination and electrocardiogram findings but imaging is usually central to confirming the diagnosis, establishing a cause and guiding therapy. The diagnostic pathway of PAH involves a variety of complimentary investigations of which computed tomography pulmonary angiography (CTPA) has established a central role both in helping identify an underlying cause for PAH and assessing resulting functional compromise. In particular CTPA is considered as the gold standard technique for the diagnosis of thromboembolic disease. This article reviews the CTPA evaluation in PAH, describing CTPA techniques, a systematic approach to interpretation and spectrum of key imaging findings. PMID:26029645

  6. Multi-detector CT assessment in pulmonary hypertension: techniques, systematic approach to interpretation and key findings

    PubMed Central

    Lewis, Gareth; Reynolds, John H.; Ganeshan, Arul; Ment, Jerome

    2015-01-01

    Pulmonary arterial hypertension (PAH) may be suspected based on the clinical history, physical examination and electrocardiogram findings but imaging is usually central to confirming the diagnosis, establishing a cause and guiding therapy. The diagnostic pathway of PAH involves a variety of complimentary investigations of which computed tomography pulmonary angiography (CTPA) has established a central role both in helping identify an underlying cause for PAH and assessing resulting functional compromise. In particular CTPA is considered as the gold standard technique for the diagnosis of thromboembolic disease. This article reviews the CTPA evaluation in PAH, describing CTPA techniques, a systematic approach to interpretation and spectrum of key imaging findings. PMID:26029645

  7. Unusual Congenital Aortic Anomaly with Rare Common Celiamesenteric Trunk Variation: MR Angiography and Digital Substraction Angiography Findings

    SciTech Connect

    Tosun, Ozgur [Ankara Ataturk Education and Research Hospital, Department of Radiology (Turkey)], E-mail: ztosun@yahoo.com; Sanlidilek, Umman [Ankara University School of Medicine, Department of Radiology (Turkey); Cetin, Huseyin [Ankara Ataturk Education and Research Hospital, Department of Radiology (Turkey); Ozdemir, Ozcan [Ankara Akay Hospital, Department of Cardiology (Turkey); Kurt, Aydin; Sakarya, Mehmet Emin; Tas, Ismet [Ankara Ataturk Education and Research Hospital, Department of Radiology (Turkey)

    2007-09-15

    Magnetic resonance angiography and digital substraction angiography (DSA) findings in a case with a rare congenital thoracoabdominal aortic hypoplasia and common celiamesenteric trunk variation with occlusion of infrarenal abdominal aorta are described here. To our knowledge, this aortic anomaly has not been previously described in the English literature. DSA is the optimum imaging modality for determination of aortic hypoplasia, associated vascular malformations, collateral vessels, and direction of flow within vessels.

  8. Naeglaeria infection of the central nervous system, CT scan findings: a case series.

    PubMed

    Naqi, Rohana; Azeemuddin, Muhammad

    2013-03-01

    The imaging findings in four cases of a rare infection of the central nervous system caused by amoebae, Naeglaeria fowleri are presented. Naeglaeria fowleri are pathogenic free-living amoebae. They cause primary amoebic meningoencephalitis (PAM), a rapidly fatal disease of the central nervous system. The computed tomography brain findings in 3 (75%) of our cases of pan amoebic meningoencephalitis showed non-specific brain oedema; 2 (66%) of these cases also had moderate hydrocephalus and among that 1 (50%) case showed an old lacunar infarction in peri-ventricular region. In the remaining 1 (25%) case the scan was normal with no evidence of oedema or abnormal lesion. Out of three cases with diffuse brain oedema, postcontrast images showed abnormal meningeal enhancement throughout the brain parenchyma in 1 (33%) case. However, no definite focal enhancing lesion was noted. In the rest of the cases, no abnormal parenchymal or meningeal enhancement was seen on post-contrast images. PMID:23914650

  9. Hepatic schwannoma: imaging findings on CT, MRI and contrast-enhanced ultrasonography.

    PubMed

    Ota, Yu; Aso, Kazunobu; Watanabe, Kenji; Einama, Takahiro; Imai, Koji; Karasaki, Hidenori; Sudo, Ryuji; Tamaki, Yosui; Okada, Mituyoshi; Tokusashi, Yosihiko; Kono, Toru; Miyokawa, Naoyuki; Haneda, Masakazu; Taniguchi, Masahiko; Furukawa, Hiroyuki

    2012-09-21

    A primary benign schwannoma of the liver is extremely rare and is difficult to preoperatively discriminate from a malignant tumor. We compared the imaging and pathological findings, and examined the possibility of preoperatively diagnosing a benign liver schwannoma. A 72-year-old woman was admitted to our hospital because of a 4.6-cm mass in the liver. A malignant tumor was suspected, and a right hepatectomy was performed. After this, the diagnosis of a primary benign schwannoma of the liver was made through pathological examination. Contrast-enhanced ultrasonography (CEUS) with Sonazoid showed minute blood flows into the septum and solid areas of the tumor in the vascular phase; most likely due to increased arterial flow associated with infiltration of chronic inflammatory cells. In the postvascular phase, CEUS showed contrast defect of cystic areas and delayed enhancement of solid areas; most likely due to aggregation of siderophores. Because discriminating between a benign and malignant schwannoma of the liver is difficult, surgery is generally recommended. However, the two key findings from CEUS may be useful in discriminating ancient schwannoma by recognizing the hemorrhage involved in the secondary degeneration and aggregation of siderophores. PMID:23002371

  10. Pseudogout in the temporomandibular joint with imaging, arthroscopic, operative, and pathologic findings. Report of an unusual case.

    PubMed

    Laviv, Amir; Sadow, Peter M; Keith, David A

    2015-06-01

    The authors present a case of a 60-year-old woman with a destructive painful condition in the right temporomandibular joint (TMJ) that proved to be calcium pyrophosphate crystal deposits at subsequent biopsy examination. The patient presented with the chief complaints of pain and limitation that had not resolved with splint therapy, medications, and habit control. Magnetic resonance imaging studies showed internal derangement without reduction. Right TMJ arthroscopy with manipulation of the jaw under anesthesia showed unique findings of fronds of synovial tissue in the posterior joint space and areas of white matter. Because there was no long-term improvement in her clinical symptoms, she subsequently underwent arthroplasty of the right joint, with the white material clearly seen at surgery, and the biopsy examination confirmed the clinical and arthroscopic impression of pseudogout. The presentation, diagnosis, pathology, and treatment of pseudogout of the TMJ are discussed. PMID:25843817

  11. Retroperitoneal ancient schwannoma presenting as an adrenal incidentaloma: CT and MR findings.

    PubMed

    Inokuchi, Taku; Takiuchi, Hidekazu; Moriwaki, Yuji; Ka, Tuneyoshi; Takahashi, Sumio; Tsutsumi, Zenta; Shima, Hiroki; Hirota, Seiichi; Yamamoto, Tetsuya

    2006-12-01

    A 35-year-old woman was referred to our institution for additional examinations to evaluate bilateral suprarenal masses incidentally found on abdominal ultrasonographic images obtained during an annual medical health checkup. Our computed tomographic scans showed bilateral and well-circumscribed low-density suprarenal masses, while MRI revealed the tumors to be heterogeneous with low intensity on T1-weighted images and high intensity on T2-weighted images. A laparoscopic adrenalectomy was performed under the suspicion of a malignant tumor, such as a malignant fibrous histiocytoma. Pathologic findings indicated a retroperitoneal ancient schwannoma of two histologic types: Antoni A and Antoni B. We considered that elucidation of the characteristic features of a schwannoma would provide helpful preoperative information for diagnosis. PMID:17145411

  12. Metallosis and Metal-Induced Synovitis Following Total Knee Arthroplasty: Review of Radiographic and CT Findings

    PubMed Central

    Romesburg, Jason W.; Wasserman, Paul L.; Schoppe, Candace H.

    2010-01-01

    Metallosis and metal-induced synovitis are well-recognized complications of metal-backed polyethylene joint prostheses and have been frequently described in the orthopedic surgery literature; however, relatively fewer articles discussing the radiologic aspects of this complication have been published. To illustrate the importance of radiologic findings in the diagnosis and management of these patients, we present a case of metallosis and metal-induced synovitis complicating two revisions of a total knee arthroplasty, caused by polyethylene liner wear and dissociation of the polyethylene liner from the metal-backed patellar prosthesis. Specific attention is given to reviewing signs that aid in diagnosis, such as the “bubble sign,” “cloud sign,” and “metal-line signs.” PMID:22470753

  13. Prediction of Nodal Involvement in Primary Rectal Carcinoma without Invasion to Pelvic Structures: Accuracy of Preoperative CT, MR, and DWIBS Assessments Relative to Histopathologic Findings

    PubMed Central

    Zhou, Jun; Zhan, Songhua; Zhu, Qiong; Gong, Hangjun; Wang, Yidong; Fan, Desheng; Gong, Zhigang; Huang, Yanwen

    2014-01-01

    Objective To investigate the accuracy of preoperative computed tomography (CT), magnetic resonance (MR) imaging and diffusion-weighted imaging with background body signal suppression (DWIBS) in the prediction of nodal involvement in primary rectal carcinoma patients in the absence of tumor invasion into pelvic structures. Methods and Materials Fifty-two subjects with primary rectal cancer were preoperatively assessed by CT and MRI at 1.5 T with a phased-array coil. Preoperative lymph node staging with imaging modalities (CT, MRI, and DWIBS) were compared with the final histological findings. Results The accuracy of CT, MRI, and DWIBS were 57.7%, 63.5%, and 40.4%. The accuracy of DWIBS with higher sensitivity and negative predictive value for evaluating primary rectal cancer patients was lower than that of CT and MRI. Nodal staging agreement between imaging and pathology was fairly strong for CT and MRI (Kappa value?=?0.331 and 0.348, P<0.01) but was relatively weaker for DWIBS (Kappa value?=?0.174, P<0.05). The accuracy was 57.7% and 59.6%, respectively, for CT and MRI when the lymph node border information was used as the criteria, and was 57.7% and 61.5%, respectively, for enhanced CT and MRI when the lymph node enhancement pattern was used as the criteria. Conclusion MRI is more accurate than CT in predicting nodal involvement in primary rectal carcinoma patients in the absence of tumor invasion into pelvic structures. DWIBS has a great diagnostic value in differentiating small malignant from benign lymph nodes. PMID:24695111

  14. Orbital granulocytic sarcoma: an unusual presentation of acute myelocytic leukemia.

    PubMed

    Stein-Wexler, Rebecca; Wootton-Gorges, Sandra L; West, Daniel C

    2003-02-01

    Granulocytic sarcoma is an unusual manifestation of acute myelogenous leukemia in children and presents a diagnostic dilemma when it precedes the development of systemic disease. We present CT and MRI findings of an extraconal mass proven to be granulocytic sarcoma in a 6-year-old otherwise healthy boy with several months' history of worsening unilateral proptosis. This case is unique in providing exquisite CT and MRI correlation and in demonstrating rapid response to therapy. Further, as cytogenetics were positive for the t(8,21) translocation, this case provides opportunity for discussion of the associated incidence of this translocation and concomitant better prognosis. PMID:12557072

  15. 75 FR 38148 - Finding of No Significant Impact Related to Approval of the Mallinckrodt C-T Phase 2...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ...was under contract with the Manhattan Engineering District and the...facility associated with the C-T project meet NRC(s release criteria...elected to decommission the C-T project areas of the site in two phases...Phase 1 of the decommissioning project was completed in February...

  16. Malignant Pleural Mesothelioma Caused by Environmental Exposure to Asbestos or Erionite in Rural Turkey: CT Findings in 84

    Microsoft Academic Search

    Ahmet Altay; Ziya Toros; Muzaffer Eryllmaz; Salih Emri; Okhan Akhan; Yusuf Izzettin Barl

    OBJECTIVE. Malignant pleural mesothelioma In rural Turkey frequently results from environmental exposure to tremolite asbestos or fibrous zeolite (erionite). The aim of this study was to determine the CT features of malignant pleural mesothelloma in patients exposed to asbestos or erlonite. MATERIALS AND METHODS. The CT scans of 84 patients with proved malignant pleural mesothelioma were retrospectively evaluated. Twenty patients

  17. A new classification of peri-articular heterotopic ossification of the hip associated with neurological injury: 3D CT scan assessment and intra-operative findings.

    PubMed

    Arduini, M; Mancini, F; Farsetti, P; Piperno, A; Ippolito, E

    2015-07-01

    In this paper we propose a new classification of neurogenic peri-articular heterotopic ossification (HO) of the hip based on three-dimensional (3D) CT, with the aim of improving pre-operative planning for its excision. A total of 55 patients (73 hips) with clinically significant HO after either traumatic brain or spinal cord injury were assessed by 3D-CT scanning, and the results compared with the intra-operative findings. At operation, the gross pathological anatomy of the HO as identified by 3D-CT imaging was confirmed as affecting the peri-articular hip muscles to a greater or lesser extent. We identified seven patterns of involvement: four basic (anterior, medial, posterior and lateral) and three mixed (anteromedial, posterolateral and circumferential). Excellent intra- and inter-observer agreement, with kappa values > 0.8, confirmed the reproducibility of the classification system. We describe the different surgical approaches used to excise the HO which were guided by the 3D-CT findings. Resection was always successful. 3D-CT imaging, complemented in some cases by angiography, allows the surgeon to define the 3D anatomy of the HO accurately and to plan its surgical excision with precision. Cite this article: Bone Joint J 2015; 97-B:899-904. PMID:26130343

  18. Bifid mandibular condyle: CT and MRI appearance.

    PubMed

    Tutar, Onur; Bas, Ahmet; Gülsen, Gökçe; Bayraktarov, Elmar

    2012-01-01

    Bifid mandibular condyle (BMC) is a rare asymptomatic morphological alteration with no predilection for age group or gender. Its morphology varies from a shallow groove to two condylar heads with separate necks, oriented mediolaterally or anteroposteriorly. This report describes an unusual case of bilateral mediolateral bifid condyle in a 24-year-old female patient with the main complaint of mouth-opening limitation. MRI and CT findings revealed bilateral bifid condyle. PMID:22922936

  19. CT Findings of Risk Factors for Persistent Type II Endoleak from Inferior Mesenteric Artery to Determine Indicators of Preoperative IMA Embolization

    PubMed Central

    Matsuda, Hitoshi; Sanda, Yoshihiro; Morita, Yoshiaki; Minatoya, Kenji; Kobayashi, Junjiro; Naito, Hiroaki

    2014-01-01

    Purpose: To identify the computed tomography (CT) findings of persistent type II endoleak from the inferior mesenteric artery (IMA) which indicate the need for preoperative IMA embolization. Materials and Methods: Included were 120 patients (96 males, 49–93 years old, mean: 77.7) who underwent endovascular aortic aneurysm repair (EVAR) between June 2007 and October 2010. The relationship between persistent type II endoleak and CT findings of IMA orifice was examined. Results: CT showed no type II endoleak from IMA in 106 patients (89%; Group N), and transient type II endoleak from IMA in 10 patients (8.3%; Group T). CT showed persistent type II endoleak from IMA in 4 patients (3.3%; Group P) and three of them underwent reintervention. Univariate Cox-Mantel test analysis indicated that stenosis (p = 0.0003) and thrombus (p = 0.043) in IMA orifice were significant factors for persistent type II endoleak. The ratios of patients with proximal IMA more than 2.5 mm diameter in Groups N, Y, and P were 26/106 (24%), 5/10 (50%) and 4/4 (100%), respectively. Conclusion: Indicators for embolization of IMA prior to EVAR for the prevention of type II endoleak appear to be: (1) more than 2.5 mm in diameter and (2) no stenosis due to calcification or mural thrombus in IMA orifice. PMID:25298829

  20. Magnetic resonance imaging (MRI) and computed tomography (CT) findings in intrathecal catheter granuloma: Report of two cases

    Microsoft Academic Search

    Sir-Kit Leong; Barbara Laing; Noel Saines

    2010-01-01

    In patients who have progressive neurological deficit on a background of intrathecal morphine pump infusion, spinal catheter-associated granuloma is an important differential diagnosis. Magnetic resonance (MRI) and computed tomography (CT) are two important imaging modalities for catheter-associated granuloma. We found that catheter-associated granuloma present on MRI as a low to intermediate signal intensity mass on T1-weighted (T1W) and T2-weighted (T2W)

  1. Retrospective analysis of incidental non-trauma associated findings in severely injured patients identified by whole-body spiral CT scans

    PubMed Central

    2014-01-01

    Background Whole-body Computed Tomography (CT) scan today is considered a crucial imaging technique in the diagnostic work-up of polytrauma patients implicating a potential survival benefit. Apart from prompt identification of life threatening injuries this imaging technique provides an additional benefit by diagnosing incidental non-trauma associated medical diseases. These incidental findings might be also life threatening and warrant urgent therapy. The downside of whole-body CT is a relatively high radiation exposure that might result in an increased life time cancer risk. The aim of this study was to investigate the frequency and type of non trauma associated incidental medical findings in relation to patient age and potential clinical relevance. Methods Between January 1st 2011 and December 15th 2012, a total of 704 trauma patients were referred to our hospital’s emergency room that triggered trauma room alarm according to our trauma mechanism criteria. Of these 534 (75.8%) received a whole-body CT according to our dedicated multiple trauma protocol. Incidental Findings (IF) were assigned in three groups according to their clinical relevance. Category 1: IF with high medical relevance (urgent life threatening conditions, unless treated) needing early investigations and intervention prior to or shortly after hospital discharge. Category 2: IF with intermediate or low medical relevance, warranting further investigations. Category 3: IF without clinical relevance. Results Overall 231 IFs (43.3%) were identified, 36 (6.7%) patients had IFs with a high clinical relevance, 48 (9.0%) with a moderate or minor clinical relevance and 147 (27.5%) with no clinical relevance. The distribution of incidental findings with high or moderate relevance according to age showed an incidence of 2.6%, 6.6% and 8.8% for patients younger than 40 years, 40 to 60 years and older than 60 years, respectively. Conclusion Whole-body CT scans of trauma patients demonstrate a high rate of incidental findings. Potentially life-threatening, medical findings were found in approximately every 15th patient, predominantly aged over 40 years and presenting with minor to moderate injuries and an Injury Severity Score (ISS) of 10 or less. PMID:25187791

  2. Metastatic Melanoma: Lactate Dehydrogenase Levels and CT Imaging Findings of Tumor Devascularization Allow Accurate Prediction of Survival in Patients Treated with Bevacizumab1

    PubMed Central

    Gray, Mark R.; del Campo, Sara Martin; Zhang, Xu; Zhang, Haowei; Souza, Frederico F.; Carson, William E.; Smith, Andrew D.

    2014-01-01

    Purpose To predict survival in patients with metastatic melanoma by evaluating a combination of serum lactate dehydrogenase (LDH) level and initial computed tomographic (CT) findings of tumor devascularization after antiangiogenic therapy. Materials and Methods Consent was waived for this institutional review board–approved, retrospective, secondary analysis. Forty-four patients with metastatic melanoma received bevacizumab therapy in a randomized prospective phase II trial. Target lesions on the initial posttherapy CT images were evaluated by using Response Evaluation Criteria in Solid Tumors, the Choi criteria, and Morphology, Attenuation, Size, and Structure (MASS) criteria. Cox proportional hazards models were used to assess the association of baseline clinical variables including serum LDH and imaging findings with progression-free and overall survival. The receiver operating characteristic curve with area under the curve (AUC) was used to evaluate accuracy. Results In multivariate analysis, a high baseline serum LDH level was associated with decreased progression-free survival (hazard ratio = 1.29 for each increase of 100 IU/L; P = .002) and overall survival (hazard ratio = 1.44 for each increase of 100 IU/L; P = .001). Evaluation with MASS criteria of the first CT examination after therapy strongly predicted progression-free (P < .001) and overall (P < .001) survival. Baseline serum LDH level was moderately accurate for predicting progression-free survival at 9 months (AUC = 0.793) and overall survival at 18 months (AUC = 0.689). The combination of baseline serum LDH levels and evaluation with MASS criteria at the first CT examination after therapy had significantly higher accuracy for predicting progression-free survival at 9 months (AUC = 0.969) and overall survival at 18 months (AUC = 0.813) than did baseline serum LDH levels alone for prediction of progression-free survival (P = .020). Conclusion A combination of baseline serum LDH levels and evaluation with MASS criteria at the first CT examination after bevacizumab therapy had the highest accuracy for predicting survival in patients with metastatic melanoma. PMID:24072776

  3. A method of ROC analysis by applying item response theory (IRT) to results of 1/0 judgments on the presence or absence of abnormal findings in CT image readings

    NASA Astrophysics Data System (ADS)

    Matsumoto, Toru; Furukawa, Akira; Nisizawa, Kanae; Murao, Kohei; Hanai, Kozo; Yamamoto, Shinji; Wada, Shinichi; Sone, Shusuke

    2008-03-01

    The purpose of this study is to develop a method of ROC analysis to evaluate both the ability of individual readers to detect abnormal findings and the detectability of abnormal findings in individual cases by applying item response theory to the results of 1/0 judgments on presence of abnormal findings in CT image readings. The validity of the method was verified by the following data and methods. Twenty-four readers searched for abnormal findings in 25 cases for which there were chest CT images with defined abnormal findings. From the 1/0 judgment data for the 25 cases with CT images (column) read by the 24 readers (row), each reader's potential ability to detect the abnormal findings (?), the rate of "1" judgment by each reader, i.e. confidence level for TP and FP, P(?), and the individual image response characteristic curves with the image as the item were calculated, from which ROC curves that represent the ability of each reader to detect abnormal findings were created. In addition, from the 1/0 judgment data for the 25 cases with CT images (row) read by the 24 readers (column), the potential detectability of abnormal findings for each CT image (?) and the rate of "1" judgment for the image by readers, i.e. confidence level for TP and FP, P(?), were calculated, from which ROC curves that represent the detectability of the abnormal finding in each case were created.

  4. Clinically-Important Brain Injury and CT Findings in Pediatric Mild Traumatic Brain Injuries: A Prospective Study in a Chinese Reference Hospital

    PubMed Central

    Zhu, Huiping; Gao, Qi; Xia, Xin; Xiang, Joe; Yao, Hongli; Shao, Jianbo

    2014-01-01

    This study investigated injury patterns and the use of computed tomography (CT) among Chinese children with mild traumatic brain injury (MTBI). We enrolled children with MTBI who were treated within 24 hours of head trauma in the emergency department of Wuhan Medical Care Center for Women and Children in Wuhan, China. Characteristics of MTBIs were analyzed by age and gender. Results of cranial CT scan and clinically-important brain injury (ciTBI) for children were obtained. The definition of ciTBI was: death from TBI, intubation for more than 24 h for TBI, neurosurgery, or hospital admission of 2 nights or more. Of 455 eligible patients with MTBI, ciTBI occurred in two, and no one underwent neurosurgical intervention. CT scans were performed for 441 TBI patients (96.9%), and abnormal findings were reported for 147 patients (33.3%, 95% CI 29.0–37.8). Falls were the leading cause of MTBI (61.5%), followed by blows (18.9%) and traffic collisions (14.1%) for children in the 0–2 group and 10–14 group. For children aged between 3 and 9, the top three causes of TBI were falls, traffic collisions and blows. Leisure activity was the most reported activity when injuries occurred for all age groups. Sleeping/resting and walking ranked in the second and third place for children between 0 and 2 years of age, and walking and riding for the other two groups. The places where the majority injuries occurred were the home for the 0–2 and 3–9 years of age groups, and school for the 10–14 years of age group. There was no statistical difference between boys and girls with regard to the activity that caused the MTBI. This study highlights the important roles that parents and school administrators in the development of preventive measures to reduce the risk of traumatic brain injury in children. Also, identifying children who had a head trauma at very low risk of clinically important TBI for whom CT might be unnecessary is a priority area of research in China. PMID:24675642

  5. Spontaneous regression of hepatic adenoma in a patient with glycogen storage disease type I after hemodialysis: ultrasonographic and CT findings.

    PubMed

    Iijima, H; Moriwaki, Y; Yamamoto, T; Takahashi, S; Nishigami, T; Hada, T

    2001-09-01

    A 23-year-old woman was admitted to our hospital with recurrent gouty arthritis. Laboratory findings showed hypoglycemia, lactic acidosis, hyperlipidemia, and hyperuricemia, with normal values of serum alfa-fetoprotein (AFP) and protein induced by vitamin K absence (PIVKA-II). A diagnosis of glycogen storage disease type I (GSD-type I) was made on the basis of the laboratory data, liver biopsy findings, and partially deficient thrombocyte glucose-6-phosphatase (G-6-Pase) activity. Ultrasonography and computed tomography revealed multiple focal hepatic masses. Biopsied specimens of the lesion demonstrated a hepatic adenoma, which changed in appearance in the relatively short period between echography and computed tomography. This interesting phenomenon may highlight the importance for careful follow-up of hepatic adenomas, because of the potential of rupture, hemorrhage, or malignant transformation. During follow-up, the present patient received hemodialysis due to renal failure, and the adenoma regressed spontaneously after 8 years. Included are diagnostic images, demonstrating the association of hepatic adenoma and GSD-type I. PMID:11579951

  6. Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis.

    PubMed

    Hussain, Shahid M; Terkivatan, Türkan; Zondervan, Pieter E; Lanjouw, Esmée; de Rave, Sjoerd; Ijzermans, Jan N M; de Man, Rob A

    2004-01-01

    Focal nodular hyperplasia (FNH) is the second most common benign liver tumor after hemangioma. FNH is classified into two types: classic (80% of cases) and nonclassic (20%). Distinction between FNH and other hypervascular liver lesions such as hepatocellular adenoma, hepatocellular carcinoma, and hypervascular metastases is critical to ensure proper treatment. An asymptomatic patient with FNH does not require biopsy or surgery. Magnetic resonance (MR) imaging has higher sensitivity and specificity for FNH than does ultrasonography or computed tomography. Typically, FNH is iso- or hypointense on T1-weighted images, is slightly hyper- or isointense on T2-weighted images, and has a hyperintense central scar on T2-weighted images. FNH demonstrates intense homogeneous enhancement during the arterial phase of gadolinium-enhanced imaging and enhancement of the central scar during later phases. Familiarity with the proper MR imaging technique and the spectrum of MR imaging findings is essential for correct diagnosis of FNH. PMID:14730031

  7. Primary malignant fibrous histiocytoma of the liver MRI findings.

    PubMed

    Reed, J G; Goodman, P; Soloway, R D

    1993-01-01

    Primary malignant fibrous histiocytoma (MFH) is an unusual tumor which involves the deep fascia or skeletal muscles of the extremities or retroperitoneum. It rarely arises in the liver and, to our knowledge, the MRI appearance of primary MFH of the liver has never been reported. We present a patient with primary MFH of the liver and discuss the findings on MRI, CT, and angiography. PMID:8380881

  8. A case of boomerang dysplasia with a novel causative mutation in filamin B: identification of typical imaging findings on ultrasonography and 3D-CT imaging.

    PubMed

    Tsutsumi, Seiji; Maekawa, Ayako; Obata, Miyuki; Morgan, Timothy; Robertson, Stephen P; Kurachi, Hirohisa

    2012-01-01

    Boomerang dysplasia is a rare lethal osteochondrodysplasia characterized by disorganized mineralization of the skeleton, leading to complete nonossification of some limb bones and vertebral elements, and a boomerang-like aspect to some of the long tubular bones. Like many short-limbed skeletal dysplasias with accompanying thoracic hypoplasia, the potential lethality of the phenotype can be difficult to ascertain prenatally. We report a case of boomerang dysplasia prenatally diagnosed by use of ultrasonography and 3D-CT imaging, and identified a novel mutation in the gene encoding the cytoskeletal protein filamin B (FLNB) postmortem. Findings that aided the radiological diagnosis of this condition in utero included absent ossification of two out of three long bones in each limb and elements of the vertebrae and a boomerang-like shape to the ulnae. The identified mutation is the third described for this disorder and is predicted to lead to amino acid substitution in the actin-binding domain of the filamin B molecule. PMID:22354125

  9. A complex de novo translocation of chromosomes 4, 6 and 21 in a child with dysmorphic features and unusual hematological findings

    SciTech Connect

    Muneer, R.S.; Hopcus, D.J.; Sarale, C. [Univ. of Oklahoma Health Sciences Center, Oklahoma City, OK (United States)] [and others

    1994-09-01

    A 5 1/2-year-old white male was referred to our institution for evaluation of easy bruising confined to lower extremities since infancy. His family history is not significant with healthy parents and six normal siblings. Physical examination revealed weight and height both in 50th and 75th percentile, respectively. Major findings included macrocephaly with prominent forehead, hypertelorism with inner and outer canthus distances both above 97th percentile, epicanthus folds, normal ears with prominent upper pinnae, thin, sharp nose with pointed tip, neck with pterygium coli appearance and shortened clavicles, short thumbs with hyperconvex nails that curved around tip of fingers, abnormally bowed elbows and knee joints, prominent abdomen with omphalocele and flat feet with hypoplastic nails. He has a speech articulation problem which may be due to high arched palate. Hematological evaluation revealed PT/PTT values in normal range with prolonged bleeding time > 15 minutes. Because of abnormal elbow and knee joints, Mitromycin C Stress test was performed to rule out Fanconi`s anemia (FA). The chromosome breakage frequency was found to be within the normal range for both the patient and the control. Thus, the diagnosis of FA was ruled out. However, cytogenetic analysis revealed a three-way complex translocation between chromosomes 4, 6 and 21 with an apparent balanced carrier male karyotype: 46,XY,t(4;6;21)(4qter{r_arrow}4p16::21q21{r_arrow} 21qter;6qter{r_arrow}6p21.1::4p16{r_arrow}4pter;21pter{r_arrow} 21q21::6p21.1{r_arrow}6pter). Both parents have normal chromosomes.

  10. Finding Unusual Correlation Using Matrix Decompositions

    Microsoft Academic Search

    David B. Skillicorn

    2004-01-01

    \\u000a One important aspect of terrorism detection is the ability to detect small-scale, local correlations against a background\\u000a of large-scale, diffuse correlations. Several matrix decompositions transform correlation into other properties: for example,\\u000a Singular Value Decomposition (SVD) transforms correlation into proximity, and SemiDiscrete Decomposition (SDD) transforms\\u000a correlation into regions of increased density. Both matrix decompositions are effective at detecting local correlation in

  11. Finding unusual review patterns using unexpected rules

    Microsoft Academic Search

    Nitin Jindal; Bing Liu; Ee-Peng Lim

    2010-01-01

    In recent years, opinion mining attracted a great deal of research attention. However, limited work has been done on detecting opinion spam (or fake reviews). The problem is analogous to spam in Web search [1, 9 11]. However, review spam is harder to detect because it is very hard, if not impossible, to recognize fake reviews by manually reading them

  12. CT scan

    MedlinePLUS

    Risks of CT scans include: Allergic reaction to contrast dye Being exposed to radiation CT scans expose you to more radiation than regular x-rays. Having many x-rays or CT scans over time may increase ...

  13. CT and MR Imaging Findings and Their Implications in the Follow-up of Patients with Intracranial Aneurysms Treated with Endosaccular Occlusion with Onyx

    Microsoft Academic Search

    Isil Saatci; H. Saruhan Cekirge; Elisa F. M. Ciceri; Michel E. Mawad; A. Gulsun Pamuk; Aytekin Besim

    BACKGROUND AND PURPOSE: Our purpose was to describe the CT and MR features of intracranial aneurysms occluded with the liquid polymer Onyx. METHODS: At two centers, 35 aneurysms in 33 patients and 11 in nine patients were treated with the polymer. In 17 patients, adjunctive stents were placed at the aneurysm neck. All but three aneurysms originated from the internal

  14. Imaging findings of splenic hamartoma

    Microsoft Academic Search

    Ri-Sheng Yu; Shi-Zheng Zhang; Jian-Ming Hua

    AIM: To assess CT and MR manifestations and their diagnostic value in splenic hamartoma with review of literatures. METHODS: We described a woman who was accidentally found to have a splenic tumor by ultrasound of the abdomen. CT and MR findings of this splenic hamartoma were proved by pathology retrospectively. RESULTS: The CT and MR findings in this case included

  15. Unusual effect colourants

    Microsoft Academic Search

    P Gregory

    2003-01-01

    Summaries  An unusual effect colourant is one that exhibits a colour change or some other unusual effect outside the traditional colour-imparting\\u000a properties of a colourant. Il also includes novel ways of producing colour.\\u000a \\u000a Many such effects are known and commercialised. For example, holograms and optically-variable pigments, which utilise the\\u000a interference of visible light, and the electrostatic and photoconductive effects used in

  16. ATWAI 7-20-2011 GE CT120 uCT

    E-print Network

    Sabatini, David M.

    ATWAI 7-20-2011 GE CT120 uCT Quick Operation Guide #12;ATWAI 7-20-2011 CT120: Pre-Scan · Log and cradle compartment Tableside Controller #12;ATWAI 7-20-2011 CT120: Pre-Scan (Cont.) · Position specimen 3 Toggle Lasers Laser Mark Plane #12;ATWAI 7-20-2011 CT120: Scanning · Select the Scan icon · Find

  17. Unusual Spinal Dysraphic Lesions

    PubMed Central

    Pacheco, Pollyana; Wanderley, Luiz Eduardo

    2013-01-01

    Human tail and multiple spinal dysraphism are unusual congenital malformations. Human tail appeared as a prominent lesion from the lumbosacrococcygeal region, generally without connection between the tail and the neurospinal axis. Spinal dysraphisms are usually isolated, reaching 0.038% of incidence of multiple spinal dysraphisms in the same child. There were three cases described of unusual spinal dysraphic lesions: two cases of human tail and a case of a multiple thoracic myelomeningocele. The literature about diagnosis and treatment was reviewed. Microsurgical technique was performed to provide better exploration of the lesions, and resection could be done in those congenital malformations, without morbidity. PMID:24194997

  18. Rare and challenging extra-axial brain lesions: CT and MRI findings with clinico-radiological differential diagnosis and pathological correlation

    PubMed Central

    Demir, Mustafa Kemal; Yap?c?er, Özlem; Onat, Elif; Tokta?, Zafer Orkun; Akak?n, Ak?n; Urgun, Kamran; K?l?ç, Türker

    2014-01-01

    There are many kinds of extra-axial brain tumors and tumor-like lesions, and definitive diagnosis is complicated in some cases. In this pictorial essay, we present rare and challenging extra-axial brain lesions including neuroenteric cyst, primary leptomeningeal melanomatosis, isolated dural neurosarcoidosis, intradiploic epidermoid cyst, ruptured dermoid cyst, intraventricular cavernoma, and cavernous hemangioma of the skull with imaging findings and clinico-radiological differential diagnosis, including the pathologic correlation. Familiarity with these entities may improve diagnostic accuracy and patient management. PMID:25010368

  19. CT features of abdominal plasma cell neoplasms

    Microsoft Academic Search

    J. Monill; J. Pernas; E. Montserrat; C. Pérez; J. Clavero; A. Martinez-Noguera; R. Guerrero; S. Torrubia

    2005-01-01

    The aim of this study was to describe the CT features of abdominal plasma cell neoplasms. We reviewed CT imaging findings in 11 patients (seven men, four women; mean age 62 years) with plasma cell neoplasms and abdominal involvement. Helical CT of the entire abdomen and pelvis was performed following intravenous administration of contrast material. Images were analyzed in consensus

  20. Identifying Unusual Galaxies

    NSDL National Science Digital Library

    In this activity, students match unusual galaxies with their distinctive names and justify their reasoning. Students discover that often, galaxies acquire their names based upon how they appear to observers. This activity includes a student worksheet and background information for the teacher. This is activity four in "The Hidden Lives of Galaxies" information and activity booklet.

  1. FDG PET/CT in follicular dendritic cell sarcoma with extensive peritoneal involvement.

    PubMed

    Dong, Aisheng; Wang, Yang; Zuo, Changjing

    2014-06-01

    Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that originates from follicular dendritic cells. A 33-year-old woman was referred because of a 2-month history of lower abdominal fullness. Enhanced T1-weighted MR images showed enhancement of the thickened pelvic peritoneum. FDG PET/CT was performed showing multiple FDG-avid lymph nodes in the parapharyngeal, bilateral supraclavicular, left axillary, mediastinal, and abdominal regions, and intense FDG uptake in the thickened mesentery and peritoneum. Pathologic findings of both the left supraclavicular lymph node and peritoneal biopsy specimens were consistent with high-grade FDCS. In this case, extensive peritoneal involvement by FDCS was unusual. PMID:24476636

  2. Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis

    PubMed Central

    2011-01-01

    During spermatogenesis, spermatogonial stem cells, undifferentiated and differentiated spermatogonia, spermatocytes, spermatids and spermatozoa all express specific antigens, yet the functions of many of these antigens remain unexplored. Studies in the past three decades have shown that many of these transiently expressed genes in developing germ cells are proto-oncogenes and oncogenes, which are expressed only in the testis and various types of cancers in humans and rodents. As such, these antigens are designated cancer/testis antigens (CT antigens). Since the early 1980s, about 70 families of CT antigens have been identified with over 140 members are known to date. Due to their restricted expression in the testis and in various tumors in humans, they have been used as the target of immunotherapy. Multiple clinical trials at different phases are now being conducted with some promising results. Interestingly, in a significant number of cancer patients, antibodies against some of these CT antigens were detected in their sera. However, antibodies against these CT antigens in humans under normal physiological conditions have yet to be reported even though many of these antigens are residing outside of the blood-testis barrier (BTB), such as in the basal compartment of the seminiferous epithelium and in the stem cell niche in the testis. In this review, we summarize latest findings in the field regarding several selected CT antigens which may be intimately related to spermatogenesis due to their unusual restricted expression during different discrete events of spermatogenesis, such as cell cycle progression, meiosis and spermiogenesis. This information should be helpful to investigators in the field to study the roles of these oncogenes in spermatogenesis. PMID:22319669

  3. Unusual causes of pneumothorax.

    PubMed

    Ouellette, Daniel R; Parrish, Scott; Browning, Robert F; Turner, J Francis; Zarogoulidis, Konstantinos; Kougioumtzi, Ioanna; Dryllis, Georgios; Kioumis, Ioannis; Pitsiou, Georgia; Machairiotis, Nikolaos; Katsikogiannis, Nikolaos; Tsiouda, Theodora; Madesis, Athanasios; Karaiskos, Theodoros; Zarogoulidis, Paul

    2014-10-01

    Pneumothorax is divided to primary and secondary. It is a situation that requires immediate treatment, otherwise it could have severe health consequences. Pneumothorax can be treated either by thoracic surgeons, or pulmonary physicians. In our current work, we will focus on unusual cases of pneumothorax. We will provide the etiology and treatment for each case, also a discussion will be made for each situation. PMID:25337394

  4. [An unusual leading symptom].

    PubMed

    von Felten, Claudia; Eberhard, Stephan

    2014-08-01

    We report the case of a 81-year-old male with a long standing history of progressive dyspnea and depression. In spite of extensive cardiological, pneumological and neurological investigations the reason for his complaints remained unclear. Known for a parasellar meningioma MRI scans were repeated, but were shown to be stable. Finally endocrine investigations revealed the presence of a panhypopituitarism explaining the unusual clinical picture. PMID:25097165

  5. Lacaziosis - unusual clinical presentation.

    PubMed

    Sousa, Pétra Pereira de; Schettini, Antonio Pedro Mendes; Rodrigues, Carlos Alberto Chirano; Westphal, Danielle Cristine

    2015-01-01

    Lacaziosis or Jorge Lobo's disease is a fungal, granulomatous, chronic infectious disease caused by Lacazia loboi, which usually affects the skin and subcutaneous tissue. It is characterized by slow evolution and a variety of cutaneous manifestations with the most common clinical expression being nodular keloid lesions that predominate in exposed areas. We report the case of a patient who had an unusual clinical presentation, with a single-plated lesion on the back. Histopathological examination confirmed the diagnosis of Lacaziosis. PMID:25831004

  6. Unusual causes of pneumothorax

    PubMed Central

    Ouellette, Daniel R.; Parrish, Scott; Browning, Robert F.; Turner, J. Francis; Zarogoulidis, Konstantinos; Kougioumtzi, Ioanna; Dryllis, Georgios; Kioumis, Ioannis; Pitsiou, Georgia; Machairiotis, Nikolaos; Katsikogiannis, Nikolaos; Tsiouda, Theodora; Madesis, Athanasios; Karaiskos, Theodoros

    2014-01-01

    Pneumothorax is divided to primary and secondary. It is a situation that requires immediate treatment, otherwise it could have severe health consequences. Pneumothorax can be treated either by thoracic surgeons, or pulmonary physicians. In our current work, we will focus on unusual cases of pneumothorax. We will provide the etiology and treatment for each case, also a discussion will be made for each situation. PMID:25337394

  7. CT and MRI of diffuse lobar involvement pattern in liver pathology.

    PubMed

    Karçaaltincaba, Mu?turay; Sirlin, Claude B

    2011-12-01

    Focal, segmental, and diffuse liver pathologies have been described in the literature. This article describes a pattern in which liver pathology is confined to a lobe. This lobar pattern has not been described previously to our knowledge. Herein, we illustrate computed tomography (CT) and magnetic resonance imaging (MRI) findings of diffuse lobar involvement patterns in various liver conditions. Diffuse lobar involvement can be observed in benign (steatosis, hepatic iron overload, cholestasis, perfusion alterations, infarction, alveolar hydatid cysts, trauma, and hemangiomas) and primary malignant (hepatocellular carcinoma) pathologies. Diffuse lobar involvement in metastatic disease appears to be rare. Due in part to their potentially unusual appearances, the diagnosis of lobar pathologies using imaging can be challenging, and entities with lobar patterns can cause diagnostic confusion. Liver MRI can be used as a problem-solving tool for diffuse lobar pathologies detected on ultrasonography and CT. Inand out-of-phase MRI can help in the assessment of lobar fat accumulation. PMID:21053176

  8. Lumbosacral spine CT

    MedlinePLUS

    Spinal CT; CT - lumbosacral spine ... table that slides into the center of the CT scanner. You will need to lie on your ... creates a clearer image. In other cases, a CT of the lumbosacral spine may be done after ...

  9. Extracolonic Findings on Computed Tomography (CT) Colonography

    ClinicalTrials.gov

    2013-01-25

    Solitary Pulmonary Nodules; Multiple Pulmonary Nodules; Renal Neoplasms; Adrenal Gland Neoplasms; Aortic Aneurysm, Abdominal; Liver Neoplasms; Adnexal and Skin Appendage Neoplasms; Lymphadenopathy; Pancreatic Neoplasms

  10. CT findings in extensive tracheobronchial amyloidosis

    Microsoft Academic Search

    J. Kirchner; V. Jacobi; P. Kardos; J. Kollath

    1998-01-01

    .   Primary pulmonary amyloidosis is a rare disorder that appears in three forms: tracheobronchial, nodular parenchymal, and\\u000a diffuse parenchymal. We report the case of a 46-year-old women with extensive tracheobronchial amyloidosis which presented\\u000a with a 2-year history of dyspnea and with signs of severe fixed obstruction in pulmonary function tests. Computed tomography\\u000a of the thorax demonstrated marked thickening of the

  11. Orf with unusual features.

    PubMed

    Tahir, Moizza; Dar, Nasser Rashid; Mumtaz, Jauhar; Anwar, Irfan; Mustafvi, Sajid

    2014-11-01

    We describe a case of Orf in an immunocompetent man with no history of direct contact with farm animals. The patient presented with numerous large lesions on hands and feet including a lesion in the subungual area. Later on multiple lesions with more bizarre morphology developed on the trunk. The diagnosis was suspected on clinical appearance of the lesion and confirmed later by histopathology. We consider contact with contaminated soil as the possible source of infection as virus can survive in pastures. Awareness of unusual clinical patterns of known entities is important to avoid unnecessary interventions. PMID:25518762

  12. CT Urography for Evaluation of the Ureter.

    PubMed

    Potenta, Scott E; D'Agostino, Robert; Sternberg, Kevan M; Tatsumi, Kanayo; Perusse, Karina

    2015-01-01

    Over the past decade, computed tomographic (CT) urography has emerged as the primary imaging modality for evaluating the urinary tract in various clinical settings, including the initial workup of hematuria. With the widespread implementation of CT urography, it is critical for radiologists to understand normal ureteral anatomy and the varied appearance of pathologic ureteral conditions at CT urography. Pathologic findings at CT urography include congenital abnormalities, filling defects, dilatation, narrowing, and deviations in course. These abnormalities are reviewed, along with the indications for CT urography, current imaging protocols with specific techniques for optimal evaluation of the ureter, and dose reduction strategies. PMID:25815907

  13. Unusual infections in humans.

    PubMed Central

    Neafie, R C; Marty, A M

    1993-01-01

    Nine cases of unusual infections in humans are presented. In each case, we present the clinical history, histopathologic changes (if indicated), morphologic features of the causative organism, diagnosis, discussion, differential diagnosis, therapy, and current literature. All of the cases are illustrated with pertinent photographs. The nine cases are as follows: (i) acanthocephaliasis, the first acquired human infection by Moniliformis moniliformis in the United States; (ii) dipylidiasis, an uncommon infection caused by the dog tapeworm, Dipylidium caninum; (iii) granulomatous amebic encephalitis, caused by the recently identified leptomyxid group of amebae; (iv) schistosomiasis, a dual infection of the urinary bladder with the rare presentation of both adult worms and eggs of Schistosoma haematobium and Schistosoma mansoni in tissue sections; (v) syphilitic gastritis, an uncommon presentation of Treponema pallidum infection, in a patient with an additional incidental infection by Helicobacter pylori; (vi) microsporidiosis, the only infection caused by a Pleistophora sp. in humans; (vii) sporotrichosis, a rare disseminated infection caused by Sporothrix schenckii with numerous yeast cells in the scrotum; (viii) angiostrongyliasis, the first and only infection caused by Angiostrongylus costaricensis acquired in either Puerto Rico or the United States; and (ix) botryomycosis of the skin and subcutaneous tissue, caused by gram-positive cocci with an unusually large number of granules. Images PMID:8457979

  14. CT Diagnosis of Small-Bowel Obstruction: Efficacy in 60 Patients

    Microsoft Academic Search

    Tatsuro Fukuya; Donald A. Hawes; Charles C. Lu; Paul J. Chang; Thomas J. Barloon

    We retrospectively compared the CT findings in patients with and without surgically proved small-bowel obstruction to evaluate the role of CT in diagnosing the presence and cause of obstruction. In the patients with obstruction, we compared the CT findings with findings on plain abdominal radiographs and contrast studies of the small intestine. CT criteria used for the diagnosis of obstruction

  15. CT Scans

    Cancer.gov

    An arm or chest radiograph looks all the way through a body without being able to tell how deep anything is. A CT scan is three-dimensional. By imaging and looking at several three-dimensional slices of a body (like slices of bread) a doctor could not only tell if a tumor is present, but roughly how deep it is in the body.

  16. Acute eosinophilic ascites: an unusual form of an unusual case.

    PubMed

    Kodan, Parul; Shetty, Meenakshi A; Pavan, M R; Kariappa, Ahalya; Mahabala, Chakrapani

    2015-01-01

    Eosinophilic gastroenteritis (EGE) is an uncommon disease characterised by eosinophilic infiltration in the gastrointestinal tract. EGE may involve more than one layer of the gastrointestinal tract. Clinical features depend on the layer and location which is involved. We report an unusual case of eosinophilic ascites associated with antinuclear antibody positivity, which is an unusual variety of serosal form of EGE. PMID:25315240

  17. Bleomycin-related lung damage: CT evidence

    SciTech Connect

    Bellamy, E.A.; Husband, J.E.; Blaquiere, R.M.; Law, M.R.

    1985-07-01

    Computed tomography (CT) examinations of the chest were evaluated in 100 patients treated with bleomycin. The CT findings were compared with those of conventional chest radiographs and lung-function tests. Lung damage due to bleomycin was detected in 38% of patients by CT, while damage was detected in only 15% by radiography. Changes in appearance seen on CT scans due to bleomycin damage were compared with measurements of lung volume and gas transfer per unit lung volume. There was good correlation between severity of damage shown on CT scans and changes in lung volume. Gas transfer capabilities were reduced in most patients regardless of changes observed on CT scans. Sequential CT studies showed that complete resolution of bleomycin damage may occur within 9 months in patients with minor or moderate damage. Residual abnormalities were seen in all patients with severe damage.

  18. Computed tomography findings of a solitary extramedullary plasmacytoma of the spleen: A case report and literature review.

    PubMed

    Wang, Ying; Yang, Li; Qian, Zi-Hua; Zhu, Xiu-Liang; Yu, Ri-Sheng

    2015-01-01

    Solitary extramedullary plasmacytoma (EMP) of the spleen is a rare condition. The present study describes the case of a 23-year-old female with an extremely rare solitary EMP of the spleen. Upon examination, the tumor demonstrated unusual and notable multiple-phase spiral computed tomography (CT) findings. The lesion was a solitary, well-defined mass, with areas of variable splenic necrosis and cystic degeneration. Contrast-enhanced CT revealed progressive enhancement of the lesion in the cystic wall, internal septa and solid portion, a finding that has not previously been described. The patient underwent a splenectomy and recovered without complications. No evidence of tumor recurrence has occurred during the past two years of follow-up. To the best of our knowledge, this is the first study to examine the CT findings of a solitary EMP of the spleen. The study aimed to investigate the imaging features of solitary EMP, in particular the multiple-phase spiral CT findings, and raise awareness of the disease to reduce misdiagnoses. PMID:25435962

  19. An unusual case of incaprettamento.

    PubMed

    Focardi, Martina; Pinchi, Vilma; Defraia, Beatrice; Norelli, Gian-Aristide

    2014-06-01

    Incaprettamento is a ritual strangulation that represents a method of homicide typical of the Italian Mafia. While the victim is in the prone position, he/she is bound by one end of a rope, creating a slipknot around the throat, while the other end is used to tie the limbs behind the back. Forensic investigations reveal that in most cases, the binding of the extremities and the positioning of the victim are carried out after death due to others means and are intended to hold somebody in contempt and to punish betrayers. When the victim is tied while alive, the death is caused by self-strangulation because it is impossible to maintain the legs in this forced position. Here, we describe in detail a case with a lot of similarities to incaprettamento, although we define it as atypical because of the unusual methods of the actual binding and the circumstances in which death occurred. In fact, the investigation of the crime scene, the external and internal findings, and the histologic examination result show that this is a crime of passion. PMID:24457582

  20. Three Unusual Hungaria Asteroids

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2015-07-01

    Three Hungaria asteroids observed at the Center for Solar System Studies-Palmer Divide Station (CS3-PDS) in 2015 January-March showed unusual characteristics. 2449 Kenos, a probable member of the Hungaria collisional family, is likely to be a binary object with period P1 = 3.8481 h and P2 = 15.85 h. The 2015 observations of 6901 Roybishop, a member of the Hungaria orbital group, showed signs of a weak secondary period, P2 = 10.58 h. The secondary period is in contradiction with previous results. (23615) 1996 FK12 may be another example of so-called wide binaries, showing a strong short period, P2 = 3.6456 h, presumably due to a widely-separated satellite that is not tidally locked to a very long orbital period. The primary in such a system has a very long period, P1 = 368 h in this instance. The main question for 1996 FK12 is the validity of the long period.

  1. Cervical spine CT scan

    MedlinePLUS

    ... scan – cervical spine; Computed tomography scan – cervical spine; CT scan - cervical spine; Neck CT scan ... table that slides into the center of the CT scanner. Once you are inside the scanner, the ...

  2. CtBP, an Unconventional Transcriptional Corepressor in Development and Oncogenesis

    Microsoft Academic Search

    G Chinnadurai

    2002-01-01

    CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.

  3. Sturge Weber Syndrome--unusual presentation. .

    PubMed

    Neki, N S

    2014-01-01

    Sturge Weber Syndrome or encephalo-trigeminal angiomatosis is non-hereditary, congenital and rare disorder of unknown aetiology. It is characterised by vascular malformation with capillary venous angiomas involving face, eye and leptomeninges resulting in neurological and orbital manifestations. A case of 23 years old female presented with history of tonic-clonic convulsions, evidence of Port wine stain on face since birth, characteristic CT findings diagnosed as a case of Sturge Weber Syndrome is reported here for its rarity. PMID:25358234

  4. Cross-sectional imaging of common and unusual complications after endoscopic retrograde cholangiopancreatography.

    PubMed

    Tonolini, Massimo; Pagani, Alessandra; Bianco, Roberto

    2015-06-01

    Endoscopic retrograde cholangiopancreatography (ERCP) is currently a primarily therapeutic procedure that is extensively employed to treat several biliopancreatic disorders. Although widely considered a safe procedure, ERCP is associated with a non-negligible morbidity and occasional mortality. Due to the number and complexity of operative ERCPs performed, radiologists are increasingly faced with urgent requests for investigation of suspected post-procedural complications, which often have similar clinical and laboratory manifestations. This pictorial essay reviews the usual post-procedural CT findings, the clinical features and imaging appearances of common and unusual post-ERCP occurrences including interstitial oedematous and necrotising acute pancreatitis, haemorrhages, retroperitoneal and intraperitoneal duodenal perforations, infections and stent-related complications. Emphasis is placed on the pivotal role of multidetector CT, which is warranted after complex or prolonged ERCP procedures as it represents the most effective modality to detect and grade ERCP-related complications and to monitor nonsurgically treated patients. Timely diagnosis and optimal management require a combination of clinical and laboratory data with imaging appearances; therefore, this article aims to provide an increased familiarity with interpretation of early post-ERCP studies, particularly to triage those occurrences that require interventional or surgical treatment. In selected patients MRI allows imaging pancreatitis and abnormal collections without the use of ionising radiation. Teaching Points • Endoscopic retrograde cholangiopancreatography (ERCP) allows treating many biliopancreatic disorders.• Due to the number and complexity of procedures, post-ERCP complications are increasingly encountered.• Main complications include acute pancreatitis, haemorrhages, duodenal perforation and infections.• Diagnosis and management of complications rely on combined clinical, laboratory and imaging data.• Multidetector CT is most effective to diagnose, categorise and monitor post-ERCP complications. PMID:25716101

  5. Mesenteric panniculitis: US and CT features

    Microsoft Academic Search

    A. C. van Breda Vriesman; H. M. Schuttevaer; E. G. Coerkamp; J. B. C. M. Puylaert

    2004-01-01

    Mesenteric panniculitis is an aseptic inflammation of mesenteric fat. Before the age of ultrasonography (US) and computed tomography (CT), mesenteric panniculitis was rarely diagnosed, but today the disorder is more commonly encountered, often as an incidental imaging finding. Its exact cause remains unknown. This review illustrates the characteristic US and CT features of mesenteric panniculitis and discusses its differential diagnosis.

  6. An unusual case of rhabdomyolysis

    PubMed Central

    Gentili, Giorgio; Verdura, Claudio; Calabrò, Giuseppe; Miele, Maria Luisa

    2011-01-01

    We report an unusual case of rhabdomyolysis due to coturnism (food poisoning caused by eating quails). The patient’s clinical course is described, and possible pathogenetic mechanisms of this syndrome are briefly discussed. PMID:25984149

  7. Unusual molecular findings in autosomal recessive spinal muscular atrophy

    Microsoft Academic Search

    G Matthijs; E Schollen; E Legius; K Devriendt; N Goemans; H Kayserili; M Y Apäk; J J Cassiman

    1996-01-01

    All three types of autosomal recessive spinal muscular atrophy map to chromosome 5q11.2-q13.3 and are associated with deletions or mutations of the SMN (survival motor neurone) gene. The availability of a test to distinguish between the SMN gene and its nearly identical centromeric copy cBCD541 allows molecular diagnosis. We have analysed patients from 24 Belgian and 34 Turkish families for

  8. Two unusual, radially pulsating stars

    NASA Astrophysics Data System (ADS)

    Smolec, Rados?aw

    2014-12-01

    We present the results of pulsation modelling of two unusual radially pulsating stars pds and bep. The former variable is the first BL Her-type star showing the period doubling effect. The second variable is a member of well-detached eclipsing binary system and the first member of a new class of variable stars that mimic RR Lyrae pulsation, but have unusually small masses.

  9. Unusual variants of malignant melanoma

    Microsoft Academic Search

    Cynthia M Magro; A Neil Crowson; Martin C Mihm

    2006-01-01

    A potential diagnostic pitfall in the histologic assessment of melanoma is the inability to recognize unusual melanoma variants. Of these, the more treacherous examples include the desmoplastic melanoma, the nevoid melanoma, the so-called ‘minimal-deviation melanoma,’ melanoma with prominent pigment synthesis or ‘animal-type melanoma,’ and the malignant blue nevus. Also problematic are the unusual phenotypic profiles seen in vertical growth phase

  10. Use of ICT and its Relationship with Performance in Examinations: A Comparison of the ImpaCT2 Project's Research Findings Using Pupil-Level, School-Level and Multilevel Modelling Data

    ERIC Educational Resources Information Center

    Harrison, Colin; Lunzer, Eric A.; Tymms, Peter; Fitz-Gibbon, Carol Taylor; Restorick, Jane

    2004-01-01

    This paper reports a previously unpublished comparative analysis of data from the ImpaCT2 study investigating the relationship between students' performance in England on national tests and their reported use of information technology (particularly networked technology) for school work, at three age levels (11, 14 and 16), in English, Maths and…

  11. 111 Single centre prospective cardiac CT study to determine the prevalence of patients with coronary artery disease with a zero coronary artery calcium score and associated non-cardiac incidental findings

    Microsoft Academic Search

    A J Shah; D R Obaid; D Gopalan; J Babar; J H F Rudd

    2011-01-01

    IntroductionCardiac CT, incorporating coronary artery calcium (CAC) scoring and angiography, is being increasingly used to evaluate patients with chest pain and exclude coronary artery disease (CAD), as recommended in the recent NICE guidelines. Calcification of the coronary arteries is an excellent marker of underlying atherosclerosis, but a zero CAC score does not completely exclude the diagnosis as potentially significant non-calcified

  12. Neonatal nasopharyngeal hairy polyp: CT and MR appearance.

    PubMed

    Kochanski, S C; Burton, E M; Seidel, F G; Chanin, L R; Hensley, S; Acker, J D

    1990-01-01

    We report a rare tumor of the nasopharynx in the neonate: the teratoid or hairy polyp. In addition to the traditional modes of evaluation (barium swallow, plain radiography, and indirect laryngoscopy), CT and magnetic resonance were used to assess this unusual cause of respiratory distress and vomiting in a newborn. PMID:2229543

  13. Intracranial vascular malformations: MR and CT imaging

    SciTech Connect

    Kucharczyk, W.; Lemme-Pleghos, L.; Uske, A.; Brant-Zawadzki, M.; Dooms, G.; Norman, D.

    1985-08-01

    Twenty-four patients with 29 cerebrovascular malformations were evaluated with a combination of computed tomography (CT), angiography, and magnetic resonance (MR) imaging. Characteristics of the malformations on MR images were reviewed retrospectively, and a comparative evaluation of MR and CT images was made. Of 14 angiographically evident malformations, 13 intra-axial lesions were detected on both CT and MR images, and one dural malformation gave false-negative results on both modalities. The appearance of parenchymal lesions on MR images closely mirrored characteristic CT findings. Angiographically evident malformations have a highly characteristic appearance on MR images. MR may be more sensitive than CT in the detection of small hemorrhagic foci associated with cryptic arteriovenous malformations and may add specificity in the diagnosis of occult malformations in some cases, but MR is less sensitive than CT for the detection of small calcified malformations.

  14. Gastric interposition following transhiatal esophagectomy: CT evaluation

    SciTech Connect

    Gross, B.H.; Agha, F.P.; Glazer, G.M.; Orringer, M.B.

    1985-04-01

    Transhiatal esophagectomy without thoracotomy (THE) but with gastric interposition results in less morbidity and mortality than standard transpleural esophagectomy with thoracotomy. Barium examination has been the primary radiographic study following THE for detecting postoperative complications. The authors reviewed computed tomography (CT) scans of 21 patients who had undergone THE and correlated CT appearance with clinical status and with findings of the barium studies. Local mediastinal recurrent neoplasm was detected by CT in seven patients; barium study within 2 weeks of the CT scan failed to detect tumor recurrence in three of these patients. CT is the modality of choice for detecting locally recurrent neoplasm and distant metastases following THE and may also be helpful in patients with postoperative mediastinal abscess. Normal mediastinal CT anatomy after esophagectomy is reviewed in order to warn against pitfalls in scan interpretation.

  15. Computed Tomographic Findings of Syphilitic Aortitis: A Case Report

    SciTech Connect

    Kimura, Fumiko; Satoh, Hideyuki; Sakai, Fumikazu; Nishii, Noriko; Tohda, Joe; Fujimura, Mikihiko [Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Department of Radiology (Japan); Haruta, Shoji [Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Department of Cardiology (Japan); Yamazaki, Kenji; Endo, Masahiro [Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Department of Cardiovascular Surgery (Japan); Sakomura, Yasunari [Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Department of Cardiology (Japan); Kurosama, Hiromi [Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Department of Cardiovascular Surgery (Japan); Kasanuki, Hiroshi [Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Department of Cardiology (Japan)

    2004-03-15

    We describe the computerized tomographic (CT) findings of the aortic wall in a case of acute-phase syphilitic arteritis. The delayed phase of the contrast-enhanced CT shows a double-ring configuration of the thick thoracic aortic wall, which is similar to CT findings previously reported for Takayasu arteritis. We speculate that the resemblance of the CT findings for these two diseases accounts for their similar histopathological features.

  16. An unusual presentation of diabetic amyotrophy: myoclonus

    PubMed Central

    Zaidi, Syed Amir; Chhetri, Suresh Kumar; Lekwuwa, Godwin; Majeed, Tahir

    2013-01-01

    Diabetic amyotrophy is a distinctive form of diabetic neuropathy. It is characterised by a weakness and wasting of proximal muscles of the lower limbs with associated pain. We report a case of an elderly patient with unusual presentation of diabetic amyotrophy. He presented with myoclonic jerks and recurrent falls. Examination findings and electrophysiological studies were consistent with a diagnosis of diabetic amyotrophy. He responded well to steroids with marked improvement in strength of the lower limb muscles and complete resolution of myoclonic jerks. Diabetic amyotrophy presenting as myoclonic jerks has been rarely reported before. PMID:23386493

  17. Adenoid cystic carcinoma: An unusual presentation

    PubMed Central

    Pushpanjali, M; Sujata, D Naga; Subramanyam, S Bala; Jyothsna, M

    2014-01-01

    The adenoid cystic carcinoma is a relatively rare epithelial tumor of the major and minor salivary glands, accounting for about 1% of all malignant tumor of the oral and maxillofacial regions. Peak incidence occurs between the 5th and 6th decades of life. The clinical and pathological findings typical of this tumor include slow growth, peri-neural invasion, multiple local recurrences and distant metastasis. Herein, we report a case of adenoid cystic carcinoma of oropharynx with unusual clinical presentation. The diagnosis of this case and importance of cytology in diagnosing such cases is discussed. PMID:25328314

  18. Dedicated Breast CT: Initial Clinical Experience1

    PubMed Central

    Lindfors, Karen K.; Boone, John M.; Nelson, Thomas R.; Yang, Kai; Kwan, Alexander L. C.; Miller, DeWitt F.

    2008-01-01

    Purpose: To prospectively and intraindividually compare dedicated breast computed tomographic (CT) images with screen-film mammograms. Materials and Methods: All patient studies were performed according to protocols approved by the institutional review board and Radiation Use Committee; informed consent was obtained. A breast CT scanner prototype was used to individually scan uncompressed breasts in 10 healthy volunteers (mean age, 52.1 years) and 69 women with Breast Imaging Reporting and Data System category 4 and 5 lesions (mean age, 54.4 years). In women with lesions, breast CT images were compared with screen-film mammograms by an experienced mammographer and ranked with a continuous scale of 1–10 (score 1, excellent lesion visualization with CT and poor visualization with mammography; score 5.5, equal visualization with both modalities; and score 10, poor visualization with CT and excellent visualization with mammography). A Wilcoxon signed rank procedure was used to test the null hypothesis that ratings were symmetric at about a score of 5.5 for the entire group and for distinguishing microcalcifications versus masses and other findings and benign versus malignant lesions and for effect of breast density on lesion visualization. Women were asked to compare their comfort during CT with that during mammography on a continuous scale of 1–10. With a Wilcoxon signed rank procedure, the null hypothesis that comfort ratings were symmetric about a score of 5.5 (equal comfort with CT and mammography) was tested. Results: Overall, CT was equal to mammography for visualization of breast lesions. Breast CT was significantly better than mammography for visualization of masses (P = .002); mammography outperformed CT for visualization of microcalcifications (P = .006). No significant differences between CT and mammography were seen among benign versus malignant lesions or for effect of breast density on lesion visualization. Subjects found CT significantly more comfortable than mammography (P < .001). Conclusion: Some technical challenges remain, but breast CT is promising and may have potential clinical applications. © RSNA, 2008 PMID:18195383

  19. An initial experience with screening for colon polyps using spiral CT with and without CT colography (virtual colonoscopy)

    Microsoft Academic Search

    Douglas K. Rex; David Vining; Kenyon K. Kopecky

    1999-01-01

    Background: Computed tomographic (CT) colography (virtual colonoscopy) is a new imaging method for detection of colon polyps and cancer. Objective: To evaluate the sensitivity of CT colography for polyp detection in a population without symptoms that included persons without colon neoplasia and with radiologists blinded to colonoscopic findings. Methods: Forty-six persons without symptoms underwent spiral CT followed by same-day colonoscopy

  20. Abdominal complications of chemotherapy: findings at computed tomography.

    PubMed

    Liu, Yueyi I; Jha, Priyanka; Wang, Zhen J; Yeh, Benjamin M; Poder, Liina; Westphalen, Antonio C; Coakley, Fergus V

    2012-01-01

    Modern chemotherapy may result in an array of complications that can produce computed tomography (CT) findings in the hepatobiliary, gastrointestinal and urinary systems. This article describes the CT findings that may be seen in abdominal complications of contemporary chemotherapy. Knowledge of the varying CT appearances that can be encountered may facilitate both diagnosis and management in such cases. PMID:22226444

  1. Dercum's disease: an unusual presentation.

    PubMed

    Kosseifi, Semann; Anaya, Ervin; Dronovalli, Goutham; Leicht, Stuart

    2010-09-01

    Dercum's disease, also known as adiposis dolorosa, is a rare disease characterized by the accumulation of painful subcutaneous deposits of mature adult fatty tissue around the thighs, trunk, and upper arms and usually in a multifocal distribution. We are reporting an unusual presentation of Dercum's disease, presenting as a single painful, erythematous lesion around the left hip in a 71-year old postmenopausal woman. This report emphasizes the unusual presentation of adiposa dolorosa with a new modality for therapy. A summary of the major clinical associations, diagnostic challenges, and treatment modalities are also included in this manuscript. PMID:20659266

  2. An Unusual Case of Bilateral Granulomatous Mastitis

    PubMed Central

    Pistolese, C. A.; Di Trapano, R.; Girardi, V.; Costanzo, E.; Di Poce, I.; Simonetti, G.

    2013-01-01

    Idiopathic granulomatous mastitis (IGM) is an uncommon benign disorder of the breast. At clinical examination, IGM is characterized by an inflammatory process of the breast, usually unilateral. Possible clinical findings are palpable mass with erythematous skin, pain, sterile abscesses, fistula and nipple retraction. Mammography and ultrasound findings are not specific for IGM. Magnetic resonance imaging (MRI) is a useful tool for the differential diagnosis; it is also necessary to delineate the exact extension of the disease and to plan the correct treatment. Final diagnosis is histological. We described an unusual case of IGM with bilateral involvement in a patient with history of pacemaker implantation and IGM typical clinical symptoms. Mammography, ultrasound, and MRI examinations were performed to identify the inflammatory disorder and to plan the correct therapy. Imaging features were correlated with final histological diagnosis of IGM. PMID:23781373

  3. An unusual shotgun slug injury.

    PubMed

    Ikeda, N; Harada, A; Suzuki, T

    1989-04-01

    A fatal case with an unusual shotgun slug injury caused by an accidental discharge of a shotgun used in hunting bear is reported. The slug is old-fashioned, and is no longer on the market. Some old hunters, however, still possess such shotgun slugs, and the possibility of their use must be borne in mind. PMID:2747477

  4. An unusual cause of syncope

    Microsoft Academic Search

    Lin H. Yeo; Rachel Pyburn; Thirumalesha Desa Venkatanarayana

    2006-01-01

    We present an unusual cause for syncope that was initially thought to be due to drug therapy. Further investigations revealed the cause to be secondary to hypoadrenalism from a primary breast tumour. This case highlights the importance of arriving at the right diagnosis as signs and symptoms of adrenal insufficiency can mimic other conditions. Appropriate treatment also improves quality of

  5. An unusual case of phospholipidosis

    Microsoft Academic Search

    M. Elleder; A. Jirásek; F. šmíd; K. Harzer; D. Schlegerová

    1978-01-01

    We present the results of a structural, histochemical and lipid-chromatographic study of tissues obtained at postmortem from an unusual case of phospholipidosis. A previous biopsy of the appendix and liver (Elleder et al., 1975a) had revealed a predominance of phosphoglyceride storage, principally of lysobisphosphatidic acid (LBPA) postmortem material showed that this lipid was stored exclusively in central neurons. In the

  6. Multidetector CT and three-dimensional CT angiography for suspected vascular trauma of the extremities.

    PubMed

    Fishman, Elliot K; Horton, Karen M; Johnson, Pamela T

    2008-01-01

    The evolution of computed tomography (CT) from four to 16 to 64 sections since its inception in the late 1970s has led to more widespread use of this imaging modality in the emergent setting. CT angiography has become a crucial diagnostic technique for identifying vascular injury in the trauma patient. Regardless of the nature of the traumatic injury (eg, stab wound, gunshot wound, injury from a motor vehicle accident), use of multidetector CT with two-dimensional (2D) reformation and three-dimensional (3D) rendering allows visualization of injury to bone, muscle, and vasculature. The radiologist should be familiar with the indications for CT angiography, optimization of current multidetector CT acquisition protocols, utility of 2D and 3D displays, and CT findings in the presence of vascular injury to ensure prompt diagnosis and treatment. PMID:18480477

  7. Abdominal CT scan

    MedlinePLUS

    Computed tomography scan - abdomen; CT scan - abdomen; CAT scan - abdomen ... An abdominal CT scan makes detailed pictures of the structures inside your belly (abdomen) very quickly. This test may be used to ...

  8. Knee CT scan

    MedlinePLUS

    A computed tomography (CT) scan of the knee is test that uses x-rays to make detailed images of the knee. ... table that slides into the center of the CT scanner. When you are inside the scanner, the ...

  9. Heart CT scan

    MedlinePLUS

    ... Computed tomography scan - heart; Calcium scoring; Multi-detector CT scan - heart; Electron beam computed tomography - heart; Agaston ... table that slides into the center of the CT scanner. You will lie on your back with ...

  10. Head CT (image)

    MedlinePLUS

    CT stands for computerized tomography. In this procedure, a thin X-ray beam is rotated around the ... D image of a section through the body. CT scans are very detailed and provide excellent information ...

  11. CT scan (image)

    MedlinePLUS

    CT stands for computerized tomography. In this procedure, a thin X-ray beam is rotated around the ... D image of a section through the body. CT scans are very detailed and provide excellent information ...

  12. Normalized CT Dose Index of the CT Scanners Used in the National Lung Screening Trial

    PubMed Central

    Cody, Dianna D.; Kim, Hyun-Jung; Cagnon, Christopher H.; Larke, Frederick J.; McNitt-Gray, Michael M.; Kruger, Randell L.; Flynn, Michael J.; Seibert, J. Anthony; Judy, Philip F.; Wu, Xizeng

    2010-01-01

    The National Lung Screening Trial (NLST) includes 33 participating institutions, which performed 75, 133 lung cancer screening CT exams from 26,724 subjects during 2002–2007. For trial quality assurance reasons, CT radiation dose measurement data were collected from all multidetector-row CT scanners used in the NLST. A total of 247 measurements on 96 multi-row detector scanners were collected using a standard CT dose index (CTDI) measurement protocol. The scan parameters employed in the measurements (tube voltage, mAs and detector-channel configuration) were set according to trial-protocol for average size subjects. The normalized CTDIw (computed as CTDIw /mAs) obtained from each trial-participating scanner was tabulated. This study demonstrated a statistically significant difference in normalized CT dose index among CT scanner manufacturers, likely due to design differences such as filtration, bow-tie design and geometry. Our findings also indicated a statistically significant difference in normalized CT dose index among CT scanner models within GE, Siemens, and Philips. We also demonstrated a statistically significant difference in normalized CT dose index among all models and all manufacturers. And, we demonstrated a statistically significant difference in normalized CT dose index from CT scanners among manufacturers when grouped by 4 or 8 data channels vs 16, 32, or 64 channels, suggesting improved dose efficiency in more complex scanners. Average normalized CT dose index values varied by almost a factor of two across all scanners from all manufacturers. This study was focused on machine specific normalized CT dose index; patient dose and image quality were not addressed. PMID:20489094

  13. MRI of unusual lesions in the internal auditory canal

    Microsoft Academic Search

    A. Krainik; F. Cyna-Gorse; D. Bouccara; D. Cazals-Hatem; V. Vilgrain; A. Denys; A. Rey; O. Sterkers; Y. Menu

    2001-01-01

    We report the MRI findings of six unusual lesions of the internal auditory canal: three haemangiomas, one lipoma, one metastasis\\u000a and one traumatic neuroma. We compare the findings to those of 20 intracanalicular schwannomas. We noted the site and size\\u000a of the tumour, its signal intensity, borders and the homogeneity of enhancement were studied on T1-weighted images before\\u000a and after

  14. Unusual traits associated with Robinow syndrome.

    PubMed Central

    Sabry, M A; Ismail, E A; al-Naggar, R L; al-Torki, N A; Farah, S; al-Awadi, S A; Obenbergerova, D; Bastaki, L

    1997-01-01

    We report on some members of two unrelated families showing the characteristic features of Robinow syndrome. In a consanguineous Kuwaiti family, the index case with Robinow syndrome showed some unusual features including severe IUGR, laxity of ligaments, hyperextensible joints, redundant skin folds, severe normocytic anaemia, repeated infection, increased percentage of total T cells and CD4 positive population, reduced percentage of CD8 positive cells, and EMG abnormality. In a Pakistani family with a high degree of multigenerational consanguinity, a single case with the Robinow phenotype also had congenital heart disease, mainly involving the right side of the heart, with pulmonary stenosis, tricuspid atresia, ASD, VSD, double outlet right ventricle, and right atrial isomerism. This report suggests that the disease profile of Robinow syndrome may be extended to accommodate the unusual traits mentioned above. The association of the Robinow phenotype with congenital heart disease in case 2 of this report is consistent with the previously reported finding that congenital heart disease, particularly involving the right side of the heart, may be a prominent component of Robinow syndrome in a subset of patients. Images PMID:9321759

  15. CT of osteomyelitis of the spine

    SciTech Connect

    Golimbu, C.; Firooznia, H.; Rafii, M.

    1984-01-01

    Computed tomography (CT) scans were performed in 17 adults with osteomyelitis of the spine. The dominant features were paravertebral soft-tissue swelling, abscess formation, and bone erosion. In two patients there were no findings indicative of osteomyelitis on conventional radiographs, but CT revealed paravertebral abscesses and bone lysis, helping to establish the diagnosis of osteomyelitis, chiefly because of its ability to detect early erosion of spongy vertabral bone, disk involvement, paravertebral soft-tissue swelling or abscess, and extension of the pathology into the spinal canal. Furthermore, CT facilitated closed-needle biopsy, helping to establish the pathologic diagnosis.

  16. Incremental Value of Adenosine-induced Stress Myocardial Perfusion Imaging with Dual-Source CT at Cardiac CT Angiography1

    PubMed Central

    Rocha-Filho, Jose A.; Blankstein, Ron; Shturman, Leonid D.; Bezerra, Hiram G.; Okada, David R.; Rogers, Ian S.; Ghoshhajra, Brian; Hoffmann, Udo; Feuchtner, Gudrun; Mamuya, Wilfred S.; Brady, Thomas J.

    2010-01-01

    Purpose: First, to assess the feasibility of a protocol involving stress-induced perfusion evaluated at computed tomography (CT) combined with cardiac CT angiography in a single examination and second, to assess the incremental value of perfusion imaging over cardiac CT angiography in a dual-source technique for the detection of obstructive coronary artery disease (CAD) in a high-risk population. Materials and Methods: Institutional review board approval and informed patient consent were obtained before patient enrollment in the study. The study was HIPAA compliant. Thirty-five patients at high risk for CAD were prospectively enrolled for evaluation of the feasibility of CT perfusion imaging. All patients underwent retrospectively electrocardiographically gated (helical) adenosine stress CT perfusion imaging followed by prospectively electrocardiographically gated (axial) rest myocardial CT perfusion imaging. Analysis was performed in three steps: (a)Coronary arterial stenoses were scored for severity and reader confidence at cardiac CT angiography, (b)myocardial perfusion defects were identified and scored for severity and reversibility at CT perfusion imaging, and (c)coronary stenosis severity was reclassified according to perfusion findings at combined cardiac CT angiography and CT perfusion imaging. The sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) of cardiac CT angiography before and after CT perfusion analysis were calculated. Results: With use of a reference standard of greater than 50% stenosis at invasive angiography, all parameters of diagnostic accuracy increased after CT perfusion analysis: Sensitivity increased from 83% to 91%; specificity, from 71% to 91%; PPV, from 66% to 86%; and NPV, from 87% to 93%. The area under the receiver operating characteristic curve increased significantly, from 0.77 to 0.90 (P < .005). Conclusion: A combination protocol involving adenosine perfusion CT imaging and cardiac CT angiography in a dual-source technique is feasible, and CT perfusion adds incremental value to cardiac CT angiography in the detection of significant CAD. © RSNA, 2010 PMID:20093513

  17. Unusual Presentation of Cutaneous Leiomyoma

    PubMed Central

    Bhaskar, Sapnashree; Jaiswal, Ashok K; Madhu, SM; Santosh, KV

    2014-01-01

    Herein, we report a case of leiomyoma cutis because of its rarity and unusual presentation. The case presented with a solitary leiomyoma lesion which was painless. However, the adjacent normal appearing area was tender. A biopsy of the lesion as well as of a portion of the adjacent normal appearing area was taken, which confirmed the diagnosis of cutaneous leiomyoma. This may suggest the dormant nature of the disease which has not yet become apparent. PMID:25484434

  18. Unusual presentation of cutaneous leiomyoma.

    PubMed

    Bhaskar, Sapnashree; Jaiswal, Ashok K; Madhu, Sm; Santosh, Kv

    2014-11-01

    Herein, we report a case of leiomyoma cutis because of its rarity and unusual presentation. The case presented with a solitary leiomyoma lesion which was painless. However, the adjacent normal appearing area was tender. A biopsy of the lesion as well as of a portion of the adjacent normal appearing area was taken, which confirmed the diagnosis of cutaneous leiomyoma. This may suggest the dormant nature of the disease which has not yet become apparent. PMID:25484434

  19. Star Library: An Unusual Episode

    NSDL National Science Digital Library

    2009-02-16

    Created by Mary Richardson of Grand Valley State University, this article describes an activity that illustrates contingency table (two-way table) analysis. Students use contingency tables to analyze the "Â?Â?unusual episode" (the sinking of the ocean liner Titanic) data (from Dawson, 1995) and attempt to use their analysis to deduce the origin of the data. The activity is appropriate for use in an introductory college statistics course or in a high school AP statistics course.

  20. Abdominal catastrophes and other unusual events in continuous ambulatory peritoneal dialysis patients.

    PubMed

    Steiner, R W; Halasz, N A

    1990-01-01

    Primary bacterial peritonitis and catheter-associated infections compose the large majority of abdominal events in continuous ambulatory peritoneal dialysis (CAPD) patients. Yet occasionally primary pathology involving the abdominal viscera develops, and surgery is frequently considered. The early manifestations of intraabdominal inflammation or bleeding in patients undergoing CAPD depend on the pathological process, its access to the peritoneal cavity, and whether generalized bacterial peritonitis supervenes to obscure helpful physical findings. Clear dialysate is not a reliable sign that major pathology is absent, nor does initial stabilization of the clinical course with antibiotic therapy uniformly indicate that surgery will not be necessary. Polymicrobial peritonitis may develop in cholecystitis, pancreatitis, or from a colonic source, the latter featuring more bacterial species and more gram-negative and anaerobic organisms. A history directed at progression of symptoms and sites of abdominal discomfort and an examination for deep local tenderness and bowel incarcerated in an abdominal wall hernia are essential. Measurement of dialysate amylase and Gram stain of dialysate for food fibers may be helpful. Imaging techniques such as abdominal radiographs for dilated bowel or free subdiaphragmatic air, ultrasonography of the gallbladder or pancreas, computed tomographic (CT) scanning of the lower abdomen, and water-soluble contrast colonic studies may help identify the pathologic process. Special studies such as these should be considered early in the course of suspected unusual abdominal events in patients on CAPD. PMID:2403751

  1. An unusual breast mass: primary synovial sarcoma

    PubMed Central

    Doyle, Victoria J; Bateman, Adrian C; Theaker, Jeffery M

    2013-01-01

    We describe a 54-year-old woman presenting with mastalgia and a 6?mm breast lesion on imaging. Core biopsy revealed a lesion characterised by a predominant epithelioid and a minor spindle cell component. Our differential diagnosis included intraduct papilloma/adenoma and adenomyoepithelioma. However, initial immunohistochemistry did not support these diagnoses and further immunohistochemistry raised the possibility of a synovial sarcoma. This was confirmed with the finding, using fluorescence in-situ hybridisation, of the characteristic translocation t(x; 18) (p11.2; q11.2). Establishing a diagnosis of synovial sarcoma at unusual sites may be difficult, especially when limited tissue is available, for example, within a core biopsy. In this case, immunohistochemistry was useful, but cytogenetics was the key additional investigation. It is important to consider the possibility of rare tumours when the morphological and immunohistochemical features of a lesion initially appear conflicting or inconclusive. PMID:23784772

  2. CT in hepatic cirrhosis and chronic hepatitis.

    PubMed

    Valls, Carlos; Andía, Eduard; Roca, Yolanda; Cos, Mònica; Figueras, Juan

    2002-02-01

    Cirrhosis is a diffuse liver disease with premalignant potential in which hepatocellular carcinoma (HCC) frequently develops. The hemodynamics of contrast material are the key to diagnosis of focal liver lesions with computed tomography (CT). Lesions with arterial-dominant vascularity, such as HCC, show brisk enhancement during the arterial phase, whereas lesions with portal blood supply can appear as hyperenhancing lesions in the portal phase. The advent of helical CT has significantly improved the CT examination of the liver because the arterial phase can be displayed independently of the portal phase. The addition of arterial phase imaging to conventional portal phase imaging seems to improve tumor detection and characterization. Although HCC is the single most frequent tumor seen in chronic liver disease, other lesions such as peripheral cholangiocarcinoma and hemangioma should be considered in the differential diagnosis. Optimization of helical CT techniques may allow better detection and characterization of these lesions. In addition to tumor detection, CT plays an important role in preoperative staging of HCC as well as in preoperative assessment of patient candidates to hepatic transplantation. The use of CT angiography with maximum intensity projection techniques may allow for better preoperative work-up and vascular mapping in HCC patients. This article shows the spectrum of helical CT findings in chronic liver disease and specifically in the imaging of HCC and other focal lesions. PMID:11866222

  3. Dural tear of unusual cause

    PubMed Central

    Kechna, Hicham; Loutid, Jaouad; Ouzzad, Omar; Hanafi, Sidi Mohamed; Hachimi, Moulay Ahmed

    2015-01-01

    Epidural analgesia is highly recommended in cancer anorectal surgery. In addition to the fight against pain it provides some benefit in allowing early rehabilitation of patients. One of the risks of this practice is the dural tear creating a cerebrospinal fluid leak (CSF) in the epidural space (EPD). Clinical features the typical positional headache, a procession of various more or less severe symptoms: nausea, vomiting, dizziness, visual or hearing impairment or radicular pain. We report a dural of unusual cause secondary of the obstruction of tuohy catheter by vertebral cartilage.

  4. CT of soft-tissue neoplasms

    SciTech Connect

    Weekes, R.G.; McLeod, R.A.; Reiman, H.M.; Pritchard, D.J.

    1985-02-01

    The computed tomographic scans (CT) of 84 patients with untreated soft-tissue neoplasms were studied, 75 with primary and nine with secondary lesions. Each scan was evaluated using several criteria: homogeneity and density, presence and type of calcification, presence of bony destruction, involvement of multiple muscle groups, definition of adjacent fat, border definition, and vessel or nerve involvement. CT demonstrated the lesion in all 84 patients and showed excellent anatomic detail in 64 of the 75 patients with primary neoplasms. The CT findings were characteristic enough to suggest the histology of the neoplasm in only 13 lesions (nine lipomas, three hemangiomas, one neurofibroma). No malignant neoplasm had CT characteristics specific enough to differentiate it from any other malignant tumor. However, malignant neoplasms could be differentiated from benign neoplasms in 88% of the cases.

  5. Fluorodeoxyglucose uptake in absence of CT abnormality on PET-CT: What is it?

    PubMed Central

    Liu, Yiyan

    2013-01-01

    The purpose of this article is to provide a pictorial review of the findings and interpretative pitfalls about focal fluorodeoxyglucose (FDG) uptake in the absence of corresponding computer tomography (CT) lesion or abnormality on an integrated positron emission tomography (PET)-CT. The integrated CT images in the PET-CT scanner allow correct co-registration and fused imaging of anatomical and functional data. On FDG PET-CT imaging, a real pathologic process often demonstrates abnormal uptake associated with a visible corresponding CT lesion or abnormality. When focal uptake is seen on PET imaging but no corresponding anatomic abnormality is visualized on the integrated CT, one should always be aware of possible mis-registration or mismatch of the PET and CT images due to the patient’s respiratory or body motion. While most of the hot spots in the absence of corresponding anatomic abnormalities are artefactual or secondary to benign etiologies, some may represent small sized or early staged neoplasm or metastases, especially in the gastrointestinal tract and skeletons. Caution should be exercised to simply diagnose a pathology based on the presence of the uptake only, or exclude the disease based on the absence of anatomic abnormality. PMID:24379932

  6. Primary combined hepatocellular-cholangiocellular sarcoma: An unusual case.

    PubMed

    Xiang, Shuai; Chen, Yi-Fa; Guan, Yan; Chen, Xiao-Ping

    2015-06-21

    Primary liver carcinosarcoma is rare. Here we report an unusual case of liver carcinosarcoma containing combined hepatocellular cholangiocarcinoma. A mass in the right liver lobe of a 45-year-old man was accidentally discovered by ultrasonic inspection and computed tomography (CT) scan. Surgical resection was performed following a diagnosis of primary liver cancer. Micropathologically, both carcinomatous and sarcomatous elements were present, and diagnosis of liver carcinosarcoma was confirmed. The carcinomatous element consisted of hepatocellular carcinoma and foci of cholangiocellular carcinoma. The sarcomatous element was composed of spindle cells and bizarre cells, as well as foci of osteosarcoma and chondrosarcoma. Hepatocellular carcinoma cells diffusely expressed both hepatocyte specific markers cytokeratin (CK) 8/18 and cholangiocyte specific markers CK19, and sarcoma cells were positive for vimentin. Interestingly, both carcinomatous and sarcomatous cells expressed epithelial membrane antigen. CD117-positive ductular reactions and small undifferentiated cells were observed. A liver progenitor cell origin of the liver carcinosarcoma was proposed. PMID:26109824

  7. Primary combined hepatocellular-cholangiocellular sarcoma: An unusual case

    PubMed Central

    Xiang, Shuai; Chen, Yi-Fa; Guan, Yan; Chen, Xiao-Ping

    2015-01-01

    Primary liver carcinosarcoma is rare. Here we report an unusual case of liver carcinosarcoma containing combined hepatocellular cholangiocarcinoma. A mass in the right liver lobe of a 45-year-old man was accidentally discovered by ultrasonic inspection and computed tomography (CT) scan. Surgical resection was performed following a diagnosis of primary liver cancer. Micropathologically, both carcinomatous and sarcomatous elements were present, and diagnosis of liver carcinosarcoma was confirmed. The carcinomatous element consisted of hepatocellular carcinoma and foci of cholangiocellular carcinoma. The sarcomatous element was composed of spindle cells and bizarre cells, as well as foci of osteosarcoma and chondrosarcoma. Hepatocellular carcinoma cells diffusely expressed both hepatocyte specific markers cytokeratin (CK) 8/18 and cholangiocyte specific markers CK19, and sarcoma cells were positive for vimentin. Interestingly, both carcinomatous and sarcomatous cells expressed epithelial membrane antigen. CD117-positive ductular reactions and small undifferentiated cells were observed. A liver progenitor cell origin of the liver carcinosarcoma was proposed. PMID:26109824

  8. Intestinal spirochaetosis: an electron microscopic study of an unusual case.

    PubMed

    Antonakopoulos, G; Newman, J; Wilkinson, M

    1982-07-01

    An unusual case of intestinal spirochaetosis is described. The rectum of a 34-year-old male, suffering from Crohn's disease and ankylosing spondylitis, was heavily infested by spirochaetes. Both absorptive and goblet cells were colonized. Spirochaetes were found not only on the luminal surface of these cells, but also within the cytoplasm, in occasional macrophages within the lamina propria and, even more surprisingly, within the occasional Schwann cell. The significance of these findings is discussed. PMID:7118085

  9. Bilateral tarsometatarsal joint injuries: An unusual mechanism producing unusual variants.

    PubMed

    Young, P S; Clement, V L; Lomax, A; Badhesha, J; Miller, R J; Mahendra, A

    2015-06-01

    Tarsometatarsal (Lisfranc) joint injuries are rare but potentially devastating conditions requiring anatomical reduction and internal fixation or arthrodesis. We describe an unusual mechanism involving forced eversion and dorsiflexion on both fully supinated feet resulting in bilateral tarsometatarsal joint injury. The injury pattern involved incongruity between the medial and middle columns extending between the cuneiform bones with associated fracture of the cuboid on the right and the cuboid, os calcis and talus on the left. Operative fixation is discussed and the clinical outcome was good at 4 years post-operatively. We believe this introduces an additional and potentially serious mechanism of injury and pattern of ligamentous and osseous disruption into the pantheon of injuries classed as Lisfranc, which surgeons should be aware of. Furthermore, we recommend attention to the mechanism of injury in consideration with classification to aid in operative reduction and fixation. PMID:25510168

  10. Unexplained Brightening of Unusual Star

    NASA Astrophysics Data System (ADS)

    1997-01-01

    Recent observations with the Hubble Space Telescope (HST) have documented an unexpected and rapid, seven-fold brightening of an unusual double star at the centre of the impressive 47 Tucanae globular cluster in the southern sky. This is the first HST observation of such a rare phenomenon. The astronomers [1] who are involved in this observational program find that this event cannot be explained by any of the common processes known to occur in such stars. The cores of globular clusters Globular clusters are like huge swarms of stars, containing about one million suns, which move around in their common gravitational field. Most galaxies contain globular clusters; around 150 are known within the confines of our Galaxy, the Milky Way. Globular clusters change with time. In particular, at some stage in the life of a globular cluster, its central region will contract whereby the stars there move closer to each other. This phenomenon is referred to as core collapse [2]. Observations with the Hubble Space Telescope (HST) have revealed enormous central densities of the order of 30,000 stars per cubic light-year in clusters with fully collapsed cores; this is to be compared with the stellar density in the solar neighborhood of only 0.003 stars per cubic light-year [3]. Binary stars in globular clusters Binary (i.e., double) stars play an important role in the evolution of globular clusters: they can delay, halt, or even reverse the process of core collapse. In this dense stellar environment, close encounters between passing stars and binaries are relatively frequent. Such events may leave the binary stars more tightly bound, and at the same time speed up the motion of the stars involved, thereby counteracting the contraction of the core. The same close stellar encounters may also produce a diverse progeny of exotic objects. The centers of globular clusters contain blue stragglers (stars that ``look'' younger than they really are), millisecond pulsars (rapidly rotating, very compact objects), both high- and low-luminosity X-ray sources , and cataclysmic variables (double stars whose light `flickers'). The kinds and numbers of these objects in cluster cores constrain the complex and as yet incompletely understood formation channels, most of which involve encounters with binaries. Many of the above exotic objects are strong emitters of ultraviolet light. The globular cluster 47 Tucanae 47 Tucanae is an impressive globular cluster that is visible with the naked eye from the southern hemisphere. It is one of the closest (distance 15,000 lightyears) and heaviest (total mass about 1 million solar masses) in our Galaxy. It contains about 1 million stars and the member stars have been intensively studied for decades. The observed structure of 47 Tucanae indicates that it is now approaching its ultimate fate during a core collapse phase. There are five known low-luminosity X-ray sources in the core of this cluster, eleven millisecond pulsars, many blue stragglers, and a centrally concentrated population of eclipsing binary stars. The observations support the idea that the population of primordial binaries in this cluster has been heavily modified by stellar encounters. The HST observations In late 1996, the group of astronomers obtained time to observe the central area of 47 Tucanae with the Hubble Space Telescope and the second Wide Field and Planetary Camera (WFPC2). During a period of more than 4 hours, a total of 15 CCD exposures were obtained through an ultraviolet filter (transmission near 3000 A), showing the thousands of individual stars in this densely populated region. Caption to ESO PR Photo 03/97 [GIF, 57k] When inspecting this material, it immediately became clear that one of the stars had undergone a substantial brightening in the course of these observations. In fact, its brightness increased by as much as 2.1 magnitudes, that is a factor of seven, in less than one hour; see the photos that accompany this Press Release. By the end of the observations, it had become the brightest star in the core of the cluster. Caption to ESO

  11. Chest CT Scan

    MedlinePLUS

    ... CT scan. On average, though, the amount of radiation will not exceed the amount a person is naturally exposed to over 3 years. The benefits of a CT scan should always be weighed against the possible risks. Rarely, people have allergic reactions to the contrast dye that's sometimes used during ...

  12. Intraventricular Hemorrhage after Epidural Blood Patching: An Unusual Complication

    PubMed Central

    Couldwell, William T.

    2014-01-01

    The authors present two cases of intraventricular hemorrhage (IVH) believed to be a result of epidural blood patching. The first was a 71-year-old woman who had new onset of nontraumatic IVH on computed tomography (CT) scan after undergoing an epidural blood patch (EBP). This amount of intraventricular blood was deemed an incidental finding since it was of very small volume to account for her overall symptoms. The second patient, a 29-year-old woman, was found to have nontraumatic IVH three days after undergoing an EBP. This was seen on CT scan of the head for workup of pressure-like headaches, nausea, vomiting, and absence seizures. Conservative management was followed in both instances. Serial CT scan of the head in our first patient displayed complete resolution of her IVH. The second patient did not have follow-up CT scans because her overall clinical picture had improved significantly. This highlights a potential sequel of EBP that may be observed on CT scan of the head. In the event that IVH is detected, signs and symptoms of hydrocephalus should be closely monitored with the consideration for a future workup if warranted by the clinical picture. PMID:25544916

  13. CT features of nonfunctioning islet cell carcinoma

    SciTech Connect

    Eelkema, E.A.; Stephens, D.H.; Ward, E.M.; Sheedy, P.F. II

    1984-11-01

    To determine the computed tomographic (CT) characteristics of nonfunctioning islet cell carcinoma of the pancreas, the CT scans of 27 patients with that disease were reviewed. The pancreatic tumor was identified as a mass in 26 patients (96%) Of the 25 tumors evaluated with contrast enhancement, 20 became partially diffusely hyperdense relative to nearby normal pancreatic tissue. Hepatic metastases were identified in 15 patients (56%), regional lymphadenopathy in 10 (37%), atrophy of the gland proximal to the tumor in six (22%), dilatation of the biliary ducts in five (19%), and dilatation of the pancreatic duct in four (15%). The CT appearances of the nonfunctioning islet cell tumors were compared with those of 100 ordinary (ductal) pancreatic adenocarcinomas. Although the two types of tumors were sometimes indistinguishable, features found to be more characteristic of islet cell carcinoma included a pancreatic mass of unusually large size, calcification within the tumor, and contrast enhancement of either the primary tumor or hepatic metastases. Involvement of the celiac axis or proximal superior mesenteric artery was limited to ductal carcinoma.

  14. Combined 18F-FDG PET/CT Imaging for the Initial Evaluation of Glottic Cancer

    PubMed Central

    Jeong, Han-Sin; Chung, Man Ki; Choi, Joon Young; Son, Young-Ik; Kim, Hyung-Jin; Hong, Sang Duk; Bok, Kwon Hyo

    2008-01-01

    Objectives The primary aim of this study was to determine whether 18F-FDG-PET/CT (PET/CT) scans provide additional diagnostic information in addition to the direct laryngoscopic examination (L/E) and contrast-enhanced CT (CT) in patients with glottic cancer during the initial evaluation. Methods Fifty-five consecutive patients with glottic cancer of the larynx that had L/E, CT and PET/CT were enrolled. The diagnostic value of each modality was compared for their accuracy in predicting the extent of the primary tumors on sub-site based analysis and the final tumor staging. The reference standards were either the surgical pathology findings or clinical/radiological follow-up outcome. Changes in patient care based on PET/CT results were compared with the treatment decisions based on L/E with CT. Results For primary tumor sub-site based analysis, the sensitivity was significantly higher for L/E (92.8%) than for PET/CT (79.4%, P=0.028). The comparisons between L/E vs. CT and CT vs. PET/CT did not reach statistical significance. As an initial tumor-staging method the L/E had a diagnostic accuracy of 76.4%, compared to 61.8% for CT and 41.8% for PET/CT. The L/E and CT were better than the PET/CT (P=0.0009 and 0.049) for the initial TNM staging. PET/CT scanning changed the clinical decision-making based on the L/E with CT results in 12.7% of cases, of whom 5.5% had no additional PET/CT related benefit. Conclusion The results of this study showed that PET/CT imaging added no clinical information benefit compared to the L/E and CT for the initial evaluation of patients with glottic cancer. PMID:19434260

  15. Hepatic focal nodular hyperplasia: angiography, CT, sonography, and scintigraphy

    Microsoft Academic Search

    J. V. Rogers; L. A. Mack; P. C. Freeny; M. L. Johnson; P. J. Sones

    1981-01-01

    Eleven patients with focal nodular hyperplasia of the liver underwent a combination of radiologic procedures, including sonography, computed tomography (CT), hepatic scintigraphy, and angiography. This paper describes the radiologic findings in this group of patients and reviews the current literature. In the present series, sonography was the most sensitive (100%) method for detection of focal nodular hyperplasia, while CT was

  16. FDG-PET/CT in lymphoma

    PubMed Central

    D'souza, Maria M; Jaimini, Abhinav; Bansal, Abhishek; Tripathi, Madhavi; Sharma, Rajnish; Mondal, Anupam; Tripathi, Rajendra Prashad

    2013-01-01

    Lymphomas are a heterogeneous group of diseases that arise from the constituent cells of the immune system or from their precursors. 18F-fludeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is now the cornerstone of staging procedures in the state-of-the-art management of Hodgkin's disease and aggressive non-Hodgkin's lymphoma. It plays an important role in staging, restaging, prognostication, planning appropriate treatment strategies, monitoring therapy, and detecting recurrence. However, its role in indolent lymphomas is still unclear and calls for further investigational trials. The protean PET/CT manifestations of lymphoma necessitate a familiarity with the spectrum of imaging findings to enable accurate diagnosis. A meticulous evaluation of PET/CT findings, an understanding of its role in the management of lymphomas, and knowledge of its limitations are mandatory for the optimal utilization of this technique. PMID:24604942

  17. UNUSUAL SONGS IN PASSERINE BIRDS1

    Microsoft Academic Search

    DONALD J. BORROR

    Unusual songs of passerine birds fall into five categories: (1) special songs, sung only under certain circumstances, and considered unusual only because they are seldom heard; (2) developmental stages of primary song; (3) songs resembling those of another species (mimicry); (4) song types outside their usual geographic range, and rare or accidental where heard; and (5) atypical songs. Songs of

  18. SNOMED CT in pathology.

    PubMed

    García-Rojo, Marcial; Daniel, Christel; Laurinavicius, Arvydas

    2012-01-01

    Pathology information systems have been using SNOMED II for many years, and in most cases, they are in a migration process to SNOMED CT. COST Action IC0604 (EURO-TELEPATH) has considered terminology normalization one of its strategic objectives. This paper reviews the use of SNOMED CT in healthcare, with a special focus in pathology. Nowadays, SNOMED CT is mainly used for concept search and coding of clinical data. Some ontological errors found in SNOMED CT are described. The Integrating the Healthcare Enterprise (IHE) initiative has fostered the use of SNOMED CT, also in Pathology, as recommended in the Supplement Anatomic Pathology Structured Reports of the IHE Anatomic Pathology Technical Framework. Rule governing concept post-coordination is also described. Some recent initiatives are trying to define a SNOMED CT subset for Pathology. The Spanish Society of Pathology has defined a subset for specimens and procedures in Pathology. Regarding diagnosis coding, the morphological abnormality sub-hierarchy of SNOMED CT need to be significantly extended and improved to become useful for pathologists. A consensus is needed to encode pathology reports with the adequate hierarchies and concepts. This will make the implementation of pathology structured reports more feasible. PMID:22925793

  19. Cirrhosis: CT and MR imaging evaluation

    Microsoft Academic Search

    Giuseppe Brancatelli; Michael P. Federle; Roberta Ambrosini; Roberto Lagalla; Alessandro Carriero; Massimo Midiri; Valérie Vilgrain

    2007-01-01

    In this article, we present the CT and MR imaging characteristics of the cirrhotic liver. We describe the altered liver morphology in different forms of viral, alcoholic and autoimmune end-stage liver disease. We present the spectrum of imaging findings in portal hypertension, such as splenomegaly, ascites and varices. We describe the patchy and lacelike patterns of fibrosis, along with the

  20. Nanoexposure, Unusual Diseases, and New Health and Safety Concerns

    PubMed Central

    Song, Yuguo; Tang, Shichuan

    2011-01-01

    Accumulating studies in animals have shown that nanoparticles could cause unusual rapid lung injury and extrapulmonary toxicity. Whether exposure of workers to nanoparticles may result in some unexpected damage as seen in animals is still a big concern. We previously reported findings regarding a group of patients exposed to nanoparticles and presenting with an unusual disease. The reported disease was characterized by bilateral chest fluid, pulmonary fibrosis, pleural granuloma, and multiorgan damage and was highly associated with the nanoparticle exposure. To strengthen this association, further information on exposure and the disease was collected and discussed. Our studies show that some kinds of nanomaterials, such as silica nanoparticles and nanosilicates, may be very toxic and even fatal to occupational workers exposed to them without any effective personal protective equipment. More research and collaborative efforts on nanosafety are required in order to prevent and minimize the potential hazards of nanomaterials to humans and the environment. PMID:22125440

  1. Unusual phenomena in ferroelectric nanostructures

    NASA Astrophysics Data System (ADS)

    Prosandeev, Sergey

    2007-03-01

    First-principles based computations are nowadays capable of tackling really complex challenges of fundamental and technological importance. For example, a dipole vortex structure has been discovered, by means of these methods, in isolated nanoparticles of ferroelectrics --which may lead to a new generation of efficient nanoscale memory devices [1]. Here, we use first-principles-based approaches to address the following issues: (i) what are the elastic signatures and field charateristics of dipole vortices in isolated ferroelectric nanodots? (ii) how to control the chirality of such dipole vortices (which is an important challenge to solve for future applications)? and (iii) what are the possible ground states of arrays of ferroelectric dots embedded in a crystal lattice? Regarding item (i), we found that the tetragonal axial ratio in the vortex state is lower than 1 (unlike in ``normal'' ferroelectric or antiferrodistortive phases), and that the electric field produced by the dipole vortex outside the dot oscillates in space when changing the polar angle of the cylindrical coordinate system. Such features can serve as fingerprints of the vortex state to experimentally confirm the existence of such unusual state. Moreover, we demonstrate that, and explain why, using inhomogeneous electric fields is an efficient solution to item (ii) [2]. Finally, it is predicted that array of embedded dots can adopt new phases, depending on the temperature and difference in polarizability between the dots and medium [3]. Atomistic details of such phases, as well as their governing mechanisms, will be provided. Coauthors: I. Ponomareva, I. Kornev, I. Naumov, and L. Bellaiche, University of Arkansas. [1] I. Naumov, L. Bellaiche, & H. Fu. ``Unusual phase transitions in ferroelectric nanodisks and nanorods, '' Nature 432, 737 (2004). [2] S. Prosandeev, I. Ponomareva, I. Kornev, I. Naumov, & L. Bellaiche. ``Controlling toroidal moment by means of an inhomogeneous static field: an ab initio study,'' Phys. Rev. Lett. 96, 237601-1-4 (2006). [3] S. Prosandeev & L. Bellaiche. ``Properties of ferroelectric nanodots embedded in a polarizable medium: atomistic simulations.,'' Phys. Rev. Lett. 97, 167601 (2006).

  2. Medical Imaging Computed Tomography (CT)

    E-print Network

    Massey, Thomas N.

    ,000 pixels! #12;Modern Example of CT Scan with the addition of Surface Shading Standard CT With Surface Sources PET-TOF #12;Four Sources PET #12;Four Sources PET-TOF #12;PET Scan MRI CT scan #12;Endocrine Gland;Basic SPECT #12;Basic Diagram #12;Brain Scans #12;Glioma CT SPEC #12;Perfusion of the left ventricle

  3. Pneumoconiosis: Comparison of imaging and pathologic findings

    SciTech Connect

    Chong, S.; Lee, K.S.; Chung, M.J.; Han, J.H.; Kwon, O.J.; Kim, T.S. [Sungkyunkwan University School of Medicine, Seoul (Republic of Korea). Samsung Medical Center

    2006-01-15

    Pneumoconiosis may be classified as either fibrotic or nonfibrotic, according to the presence or absence of fibrosis. Silicosis, coal worker pneumoconiosis, asbestosis, berylliosis, and talcosis are examples of fibrotic pneumoconiosis. Siderosis, stannosis, and baritosis are nonfibrotic forms of pneumoconiosis that result from inhalation of iron oxide, tin oxide, and barium sulfate particles, respectively. In an individual who has a history of exposure to silica or coal dust, a finding of nodular or reticulonodular lesions at chest radiography or small nodules with a perilymphatic distribution at thin-section computed tomography (CT), with or without eggshell calcifications, is suggestive of silicosis or coal worker pneumoconiosis. Magnetic resonance imaging is helpful for distinguishing between progressive massive fibrosis and lung cancer. CT and histopathologic findings in asbestosis are similar to those in idiopathic pulmonary fibrosis, but the presence of asbestos bodies in histopathologic specimens is specific for the diagnosis of asbestosis. Giant cell interstitial pneumonia due to exposure to hard metals is classified as a fibrotic form of pneumoconiosis and appears on CT images as mixed ground-glass opacities and reticulation. Berylliosis simulates pulmonary sarcoidosis on CT images. CT findings in talcosis include small centrilobular and subpleural nodules or heterogeneous conglomerate masses that contain foci of high attenuation indicating talc deposition. Siderosis is nonfibrotic and is indicated by a CT finding of poorly defined centrilobular nodules or ground-glass opacities.

  4. Pneumoconiosis: comparison of imaging and pathologic findings

    SciTech Connect

    Semin Chong; Kyung Soo Lee; Myung Jin Chung; Joungho Han; O. Jung Kwon; d Tae Sung Kim [Sungkyunkwan University School of Medicine, Seoul (Republic of Korea). Department of Radiology and Center for Imaging Science

    2006-01-15

    Pneumoconiosis may be classified as either fibrotic or nonfibrotic, according to the presence or absence of fibrosis. Silicosis, coal worker pneumoconiosis, asbestosis, berylliosis, and talcosis are examples of fibrotic pneumoconiosis. Siderosis, stannosis, and baritosis are nonfibrotic forms of pneumoconiosis that result from inhalation of iron oxide, tin oxide, and barium sulfate particles, respectively. In an individual who has a history of exposure to silica or coal dust, a finding of nodular or reticulonodular lesions at chest radiography or small nodules with a perilymphatic distribution at thin-section computed tomography (CT), with or without eggshell calcifications, is suggestive of silicosis or coal worker pneumoconiosis. Magnetic resonance imaging is helpful for distinguishing between progressive massive fibrosis and lung cancer. CT and histopathologic findings in asbestosis are similar to those in idiopathic pulmonary fibrosis, but the presence of asbestos bodies in histopathologic specimens is specific for the diagnosis of asbestosis. Giant cell interstitial pneumonia due to exposure to hard metals is classified as a fibrotic form of pneumoconiosis and appears on CT images as mixed ground-glass opacities and reticulation. Berylliosis simulates pulmonary sarcoidosis on CT images. CT findings in talcosis include small centrilobular and subpleural nodules or heterogeneous conglomerate masses that contain foci of high attenuation indicating talc deposition. Siderosis is nonfibrotic and is indicated by a CT finding of poorly defined centrilobular nodules or ground-glass opacities.

  5. Managing unusual presentations of venous thromboembolism.

    PubMed

    Ageno, Walter

    2015-04-01

    Venous thromboembolism that occurs in unusual sites is challenging because of the potential severity of presentation, the presence of some major provoking risk factors, the high prevalence of potential contraindications to antithrombotic therapies, the lack of solid evidence to guide therapeutic decisions, and because of the severity of long-term consequences. For example, venous thrombosis in the splanchnic veins frequently occurs in patients with liver cirrhosis. Not uncommonly, these patients present with concomitant active gastrointestinal bleeding, and/or low platelet count or oesophageal varices. If inadequately treated, splanchnic vein thrombosis (SVT) may further worsen portal hypertension and, thus, increase the long-term risk of bleeding. Up to 40% of patients with cerebral vein thrombosis (CVT) have signs of intracranial bleeding at the time of the diagnosis. This finding is associated with worst prognosis in terms of death or severe disability. Despite the apparent presence of a major contraindication to anticoagulation, only a timely administration of parenteral anticoagulant drugs may improve this unfavourable outcome. The available evidence on the management of these two challenging disorders, SVT and CVT, will be reviewed in this article. PMID:25682057

  6. Unusual Foreign Bodies in the Orofacial Region

    PubMed Central

    Passi, Sidhi; Sharma, Neeraj

    2012-01-01

    Foreign bodies may be deposited in the oral cavity either by traumatic injury or iatrogenically. Among the commonly encountered iatrogenic foreign bodies are restorative materials like amalgam, obturation materials, broken instruments, needles, and so forth. The discovery of foreign bodies in the teeth is a special situation, which is often diagnosed accidentally. Detailed case history, clinical and radiographic examinations are necessary to come to a conclusion about the nature, size, location of the foreign body, and the difficulty involved in its retrieval. It is more common to find this situation in children as it is a well-known fact that children often tend to have the habit of placing foreign objects in the mouth. Sometimes the foreign objects get stuck in the root canals of the teeth, which the children do not reveal to their parents due to fear. These foreign objects may act as a potential source of infection and may later lead to a painful condition. This paper discusses the presence of unusual foreign bodies—a tip of the metallic compass, stapler pin, copper strip, and a broken sewing needle impregnated in the gingiva and their management. PMID:22830058

  7. BVRI PHOTOMETRY OF 53 UNUSUAL ASTEROIDS

    SciTech Connect

    Ye, Q.-Z., E-mail: tom6740@gmail.com [Department of Atmospheric Sciences, School of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou (China)

    2011-02-15

    We present the results of BVRI photometry and classification of 53 unusual asteroids, including 35 near-Earth asteroids (NEAs), 6 high eccentricity/inclination asteroids, and 12 recently identified asteroid-pair candidates. Most of these asteroids were not classified prior to this work. For the few asteroids that have been previously studied, the results are generally in agreement. In addition to observing and classifying these objects, we merge the results from severalphotometric/spectroscopic surveys to create the largest-ever sample with 449 spectrally classified NEAs for statistical analysis. We identify a 'transition point' of the relative number of C/X-like and S-like NEAs at H {approx} 18 {r_reversible} D {approx} 1 km with confidence level at {approx}95% or higher. We find that the C/X-like:S-like ratio for 18 {<=} H < 22 is about twice as high as that of H < 18 (0.33 {+-} 0.04 versus 0.17 {+-} 0.02), virtually supporting the hypothesis that smaller NEAs generally have less weathered surfaces (therefore less reddish appearance) due to younger collision ages.

  8. Leg CT scan

    MedlinePLUS

    CAT scan - leg; Computed axial tomography scan - leg; Computed tomography scan - leg; CT scan - leg ... 2008:chap 2. Shaw AS, Dixon AK. Multidetector computed tomography. In: Adam A, Dixon AK, eds. Grainger & Allison's ...

  9. Computed Tomography (CT) -- Sinuses

    MedlinePLUS Videos and Cool Tools

    ... CT or CAT scan, is a diagnostic medical test that, like traditional x-rays, produces multiple images ... for exams. The costs for specific medical imaging tests and treatments vary widely across geographic regions. Many— ...

  10. Computed Tomography (CT) -- Head

    MedlinePLUS Videos and Cool Tools

    ... CT or CAT scan, is a diagnostic medical test that, like traditional x-rays, produces multiple images ... for exams. The costs for specific medical imaging tests and treatments vary widely across geographic regions. Many— ...

  11. Lumbar spine CT scan

    MedlinePLUS

    CAT scan - lumbar spine; Computed axial tomography scan - lumbar spine; Computed tomography scan - lumbar spine; CT - lower back ... stopping.) A computer creates separate images of the spine area, called slices. These images can be stored, ...

  12. Normal Abdominal CT

    NSDL National Science Digital Library

    Shaffer, Kitt

    Set of normal abdominal CT images with various important anatomic structures outlined, for cine viewing to gain a 3D view of the structure and its relationship to adjacent organs.Annotated: trueDisease diagnosis: Normal

  13. Normal Chest CT

    NSDL National Science Digital Library

    Shaffer, Kitt

    Set of normal chest CT images with various important anatomic structures outlined, for cine viewing to gain a 3D view of the structure and its relationship to adjacent organs.Annotated: trueDisease diagnosis: Normal

  14. Sinus CT scan

    MedlinePLUS

    CAT scan - sinus; Computed axial tomography scan - sinus; Computed tomography scan - sinus; CT scan - sinus ... polyps The cause of repeated bloody noses ( epistaxis ) Sinus infection ( sinusitis ) This results from this test may ...

  15. Rock Finding

    ERIC Educational Resources Information Center

    Rommel-Esham, Katie; Constable, Susan D.

    2006-01-01

    In this article, the authors discuss a literature-based activity that helps students discover the importance of making detailed observations. In an inspiring children's classic book, "Everybody Needs a Rock" by Byrd Baylor (1974), the author invites readers to go "rock finding," laying out 10 rules for finding a "perfect" rock. In this way, the…

  16. Intraabdominal panniculitis: clinical, radiographic, and CT features

    SciTech Connect

    Katz, M.E.; Heiken, J.P.; Glazer, H.S.; Lee, J.K.T.

    1985-08-01

    Intraabdominal panniculitis, also known as lipodystrophy, is an inflammatory condition of adipose tissue that may result in development of large masses containing necrotic fat (nodular intraabdominal panniculitis). Symptoms are secondary to inflammation or mass effect on adjacent organs. Barium studies may show nonspecific inflammatory changes and displacement of bowel loops. Computed tomography (CT) demonstrates inhomogeneous masses containing fat and soft tissue density. The diagnosis of intraabdominal panniculitis has seldom been made prospectively. However, the CT findings are characteristic and can aid in the evaluation and management of patients with this disease.

  17. Unusual breast lesions: radiologic-pathologic correlation.

    PubMed

    Feder, J M; de Paredes, E S; Hogge, J P; Wilken, J J

    1999-10-01

    Unusual lesions of the breast can present a diagnostic challenge. These lesions include systemic diseases, benign tumors, and primary and metastatic malignancies. Lymphadenopathy is the most common mammographic finding associated with collagen vascular disease. Wegener granulomatosis may manifest as an irregular, high-density mass simulating breast cancer. Diabetic fibrous mastopathy manifests at mammography as very dense breast tissue and at ultrasonography (US) as an irregular, hypoechoic mass with striking posterior acoustic shadowing simulating malignancy. Fibromatosis simulates malignancy at mammography as an irregularly shaped, uncalcified, high-density mass and at US as an irregular, hypoechoic mass with posterior acoustic shadowing. At US, granular cell tumor may manifest as a solid, poorly marginated mass with marked posterior acoustic shadowing or may appear more benign. At mammography, hamartomas are typically well-circumscribed, round to oval masses with a thin, radiopaque pseudocapsule; at US, they manifest as a sharply defined, heterogeneous oval mass or as normal glandular tissue. Phyllodes tumor manifests at mammography as a large, well-circumscribed oval or lobulated mass; at US, it usually manifests as an inhomogeneous, solid-appearing mass. At mammography, primary breast lymphoma manifests as a relatively circumscribed mass or a solitary, indistinctly marginated, uncalcified mass. Metastatic lesions may manifest mammographically as single or multiple masses or as diffuse skin thickening; at US, they tend to have circumscribed margins with low-level internal echoes. Radiologists should be familiar with the characteristic mammographic appearances of these lesions and should consider benign and systemic causes in the differential diagnosis when malignant-appearing findings are encountered. PMID:10517440

  18. Multithreaded cardiac CT

    SciTech Connect

    Kachelriess, Marc; Knaup, Michael; Kalender, Willi A. [Institute of Medical Physics, University of Erlangen, Nuernberg (Germany)

    2006-07-15

    Phase-correlated CT, as it is used for cardiac imaging, is the most popular and the most important but also the most demanding special CT application in the clinical routine, today. Basically, it fulfills the four-dimensional imaging task of depicting a quasiperiodically moving object at any desired motion phase with significantly reduced motion artifacts. Although image quality with phase-correlated reconstruction is far better than with standard reconstruction, there are motion artifacts remaining and improvements of temporal resolution are required. As a well-known alternative to simply decreasing rotation time, we consider a spiral cone-beam CT scanner that has G x-ray guns and detectors mounted. We call this a multisource or a multithreaded CT scanner. Aiming for improved temporal resolution the relative temporal resolution {tau}, which measures the fraction of a motion period that enters the image, is studied as a function of the motion rate (heart rate) and the degree of scan overlap (pitch value) for various configurations. The parameters to optimize are the number of threads G and the interthread parameters {delta}{alpha} and {delta}z, which are the angular and the longitudinal separation between adjacent threads, respectively. To demonstrate the improvements approximate image reconstruction of multithreaded raw data is performed by using a generalization of the extended parallel back projection cone-beam reconstruction algorithm [Med. Phys. 31(6), 1623-1641 (2004)] to the case of multithreaded CT. Reconstructions of a simulated cardiac motion phantom and of simulated semi-antropomorphic phantoms are presented for two and three threads and compared to the single-threaded case to demonstrate the potential of multithreaded cardiac CT. Patient data were acquired using a clinical double-threaded CT scanner to validate the theoretical results. The optimum angle {delta}{alpha} between the tubes is 90 deg.for a double-threaded system, and for triple-threaded scanners it is 60 deg.or 120 deg.. In all cases, {delta}z=0 results as an optimum, which means that the threads should be mounted in the same transversal plane. However, the dependency of the temporal resolution on {delta}z is very weak and a longitudinal separation {delta}z{ne}0 would not deteriorate image quality. The mean temporal resolution achievable with an optimized multithreaded CT scanner is a factor of G better than the mean temporal resolution obtained with a single-threaded scanner. The standard reconstructions showed decreased cone-beam artifacts with multithreaded CT compared to the single-threaded case. Our phase-correlated reconstructions demonstrate that temporal resolution is significantly improved with multithreaded CT. The clinical patient data confirm our results.

  19. Association of TGF-?1 -509 C/T, 29 C/T and 788 C/T gene polymorphisms with chronic periodontitis: a case-control study.

    PubMed

    Heidari, Zahra; Mahmoudzadeh-Sagheb, Hamidreza; Rigi-Ladiz, Mohammad Ayub; Taheri, Mohsen; Moazenni-Roodi, Abdolkarim; Hashemi, Mohammad

    2013-04-15

    The aim of this study was to investigate the possible association between TGF-?1 -509 C/T (rs1800469), 29 C/T (Prol10Leu, rs1800470) and 788 C/T (Thr263Ile, rs1800472) gene polymorphisms and chronic periodontitis (CP) in a sample of Iranian population. This case-control study was conducted on 100 CP patients and 100 healthy unrelated, age-, sex-, and ethnicity-matched. Genotyping was performed by tetra amplification refractory mutation system-polymerase chain reaction (T-ARMS-PCR) technique. Our findings showed that there was a significant difference between the groups regarding TGF-?1 29 C/T (rs1800470) polymorphism (?2=23.23, P<0.0001). The CT and TT genotypes increased the risk of CP in comparison with the CC genotype (OR=4.42, 95% CI=2.16-9.06, P<0.001 and OR=5.84, 95% CI=2.32-14.71, P<0.001, respectively). The T allele increased the risk of CP (OR=2.50, 95% CI=1.66-3.74, P<0.001) in comparison with C allele. No significant association was found among the groups regarding -509 C/T and 788 C/T variants of TGF-?1 gene. This study shows that TGF-?1 29 C/T polymorphism, but not -509 C/T and 788 C/T polymorphisms, may contribute to the development of CP in a sample of Iranian population. Further studies with larger sample sizes and different ethnicities are needed to validate our findings. PMID:23352795

  20. Thoracic Computed Tomography Findings in Malignant Mesothelioma

    PubMed Central

    Tamer Dogan, Omer; Salk, Ismail; Tas, Fikret; Epozturk, Kursat; Gumus, Cesur; Akkurt, Ibrahim; Levent Ozsahin, Sefa

    2012-01-01

    Background Malignant pleural mesothelioma (MPM) is an uncommon neoplasm. MPM occurs more frequently in patients born or living in certain villages of Turkey. Objectives We aimed to review radiological findings of MPM. Patients and Methods We reviewed the CT findings in 219 biopsy-proven MPM patients admitted to our clinic between 1993 and 2008. Results The most common CT findings included pleural thickening (n=197, 90%) classified as diffuse (n=138, 63%), nodular (n=49, 22%) and mass-type (n=16, 7%). Pleural effusion was found in 173 patients (79%), involvement of the interlobar fissures in 159 (73%), mediastinal pleural involvement in 170 (78%), volume contraction in 142 (65%), mediastinal shift in 102 (47%) and mediastinal lymphadenopathy in 54 (25%). Conclusion MPM may present with diverse radiological features. Pleural thickening and pleural effusion were the most frequent radiological findings. Thoracic CT scans might be assessed more cautiously in patients with environmental exposure to asbestos. PMID:23407863

  1. Ten uncommon and unusual variants of renal angiomyolipoma (AML): radiologic-pathologic correlation.

    PubMed

    Schieda, N; Kielar, A Z; Al Dandan, O; McInnes, M D F; Flood, T A

    2015-02-01

    Classic (triphasic) renal angiomyolipoma (AML) is currently classified as a neoplasm of perivascular epithelioid cells. For diagnosis of AML, the use of thin-section non-contrast enhanced CT (NECT) improves diagnostic accuracy; however, identifying gross fat within a very small AML is challenging and often better performed with chemical-shift MRI. Although the presence of gross intra-tumoural fat is essentially diagnostic of AML; co-existing intra-tumoural fat and calcification may represent renal cell carcinoma (RCC). Differentiating AML from retroperitoneal sarcoma can be difficult when AML is large; the feeding vessel and claw signs are suggestive imaging findings. AML can haemorrhage, with intra-tumoural aneurysm size >5 mm a more specific predictor of future haemorrhage than tumor size >4 cm. Diagnosis of AML in the setting of acute haemorrhage is complex; comparison studies or follow-up imaging may be required. Not all AML contain gross fat and imaging features of AML without visible fat overlap with RCC; however, homogeneity, hyperdensity at NECT, low T2-weighted signal intensity and, microscopic fat are suggestive features. Patients with tuberous sclerosis often demonstrate a combination of classic and minimal fat AML, but are also at a slightly increased risk for RCC and should be imaged cautiously. Several rare pathological variants of AML exist including AML with epithelial cysts and epithelioid AML, which have distinct imaging characteristics. Classic AML, although benign, can be locally invasive and the rare epithelioid AML can be frankly malignant. The purpose of this review is to highlight the imaging manifestations of 10 uncommon and unusual variants of AML using pathological correlation. PMID:25468637

  2. Unusual cause of pulmonary emboli.

    PubMed

    Vitums, V C

    1984-10-01

    Pulmonary emboli resulted due to intravasation of iophendylate during myelography the previous day. Findings consistent with pulmonary emboli in nonambulatory patients after myelography should not always be diagnosed as thromboembolic disease from blood clots. PMID:6478908

  3. Dose reduction in chest CT examination.

    PubMed

    Sulieman, A; Tammam, N; Alzimami, K; Elnour, A M; Babikir, E; Alfuraih, A

    2015-07-01

    Computed tomography (CT) examinations involve relatively high doses to patients. The objectives of this study were to optimise the radiation dose for patient during CT chest scan and to estimate the lifetime cancer risk. A total of 50 patients were studied: control group (A) (38 patients) and optimisation group (B) (12 patients). The optimisation protocol was based on CT pitch increment and lowering tube current. The mean volume CT dose index (CTDIvol) was 21.17 mGy and dose length product (DLP) was 839.0 mGy cm for Group A, and CTDIvol was 8.3 mGy and DLP was 339.7 for Group B. The overall cancer risk was estimated to be 8.0 and 3.0 cancer incidence per million for Groups A and B, respectively. The patient dose optimisation during CT chest was investigated. Lowering tube current and pitch increment achieved a radiation dose reduction of up to 60 % without compromising the diagnostic findings. PMID:25836698

  4. Some unusual minor volatile components of tomato.

    PubMed

    Buttery, Ron G; Takeoka, Gary R

    2004-10-01

    The identities and possible origins of three minor unusual volatile components of tomato are discussed. These are pentyl nitrate, the first identification of a volatile alkyl nitrate in a fresh vegetable or fruit; 5-ethyl-2(5H)-furanone, which, besides its presence in tomato, was found to be a major autoxidation product of pure (Z)-3-hexenal; and 5-ethylcyclopentene-1-carbaldehyde, a likely unusual linolenic acid oxidation product. PMID:15453697

  5. An Unusual Bone Loss Around Implants

    PubMed Central

    Rokn, Amir Reza; Sajedinejad, Neda; Yousefyfakhr, Hosnieh; Badri, Samare

    2013-01-01

    Pre-implant disease is an inflammatory process that affects the surrounding tissues of a functional osseointegrated implant. It is usually the result of a disequilibrium between the micro-flora and the defense system. This case reports a 57-year-old man with unusual bone loss around dental implants. This was an unusual case of peri-implantitis that occurred only in the implants on one side of the mouth although they were all unloaded implants. PMID:24396359

  6. Angiographic findings in tumoral calcinosis.

    PubMed

    Neeman, Ziv; Wood, Bradford J

    2003-01-01

    Tumor calcinosis is uncommon, typically manifesting as paraarticular, extracapsular soft tissue deposits containing amorphous calcium phosphate and calcium carbonate, with associated hydroxyapatite crystal. CT and MRI are the primary diagnostic radiological tools evaluating these lesions. Primary treatment is early surgical excision with wide margins, as there is a high recurrence rate. We describe the angiographic findings in tumoral calcinosis, demonstrating hypervascularity beyond the calcified mass periphery. Exact margin definition with angiography may influence management and surgical approach. PMID:12727056

  7. The need for skull radiography in patients presenting for CT

    SciTech Connect

    Tress, B.M.

    1983-01-01

    One thousand patients had both CT of the head and a conventional skull series of radiographs. Radiographic findings were abnormal in 250 patients (25%), but only 64 patients (6.4%) had diagnostically significant abnormalities at radiography that were not detected by CT. If the 163 patients who presented after acute trauma were excluded from the series, only 39 (4.7%) of the remaining patients had radiographically significant abnormal findings that were not seen at CT, and only two (0.2%) of these abnormalities could not be diagnosed by a lateral skull radiograph alone. In only five patients (0.5%) was the management actively changed because an abnormaltiy that was detected at skull radiography was not detected at CT. Thus, in nontrauma patients who have stroke, epilepsy, dementia, or non-specific symptoms without focal signs, or have recently undergone craniotomy, and who have been referred for CT, skull radiographs are not justified. In the patient with a history and findings that are strongly suggestive of a pathological disorder anywhere other than in the sella turcica, cerebello-pontine angle, and paranasal sinuses, only the lateral skull radiograph should be obtained after CT, and only if CT is equivocal.

  8. An Unusual Case of Bony Styloid Processes That Extend to the Hyoid Bone

    PubMed Central

    Gadkaree, Shekhar K.; Hyppolite, Christopher G.; Harun, Aisha; Sobel, Ryan H.; Kim, Young

    2015-01-01

    The embryological origin of the hyoid bone is a point of uncertainty, with controversy surrounding the relative contribution of the second pharyngeal arch to hyoid development. We encountered a 52-year-old male with bilateral bony styloid extension to the lesser cornu of the hyoid bone during the workup of a patient with laryngeal cancer. This embryological malformation clearly supports the hypothesis that the second pharyngeal arch gives rise to the lesser cornu and demonstrates an unusual clinical finding that may be encountered by otolaryngologists. We demonstrate the imaging findings and surgical management of this unusual anatomical variant and review the embryological basis for this rare malformation. PMID:26185698

  9. Oral Rehabilitation for Amniotic Band Syndrome: An Unusual Presentation

    PubMed Central

    Sharma, Krishna

    2015-01-01

    ABSTRACT Amniotic band syndrome (ABS) is a congenital disorder caused by entrapment of fetal parts in fibrous amniotic bands while in utero. The syndrome is underdiagnosed and its presentation is variable. The syndrome has been well described in the pediatric, orthopedic and obstetric literature; however, despite the discernable craniomaxillofacial involvement, ABS has not been reported in the dental literature very often. The present report describes a case of a patient with ABS and concomitant dental findings. How to cite this article: Hotwani K, Sharma K. Oral Rehabilitation for Amniotic Band Syndrome: An Unusual Presentation. Int J Clin Pediatr Dent 2015;8(1):55-57.

  10. Dried apricots: an unusual cause of bowel obstruction.

    PubMed

    Piotto, Lino; Gent, Roger

    2005-12-01

    We report an unusual cause of intestinal obstruction in a 16-month-old boy who presented with abdominal pain of 6 h duration. The patient was thought to have an intussusception, with plain radiographic evidence of a small-bowel obstruction (SBO). A subsequent US examination showed no evidence of intussusception but resulted in a diagnosis of SBO caused by the ingestion of whole dried apricots. The apricots had been eaten several hours earlier and had swelled in the intestinal lumen. The US imaging findings and experimental correlation are presented. PMID:16049687

  11. Computational investigation of unusual behavior in certain capillary tubes

    SciTech Connect

    Brady, Victor; Concus, Paul; Finn, Robert

    2004-03-12

    We investigate computationally two recent mathematical findings involving unusual behavior of solutions of the Young-Laplace capillary equation in cylindrical tubes of particular sections. The first concerns a configuration for which smoothing of the boundary curve at a sharp corner leads from existence to non-existence of a solution over the container section in zero gravity. The second describes a discontinuous behavior of relative rise height in nesting tubes placed vertically in an infinite reservoir. The numerical results support and quantify the mathematical predictions.

  12. Unusual manifestations of astroblastoma: a radiologic-pathologic analysis.

    PubMed

    Ganapathy, Srinivas; Kleiner, Laurence I; Mirkin, David L; Broxson, Emmett

    2009-02-01

    Astroblastoma is a very rare primary glial tumor occurring in children and young adults that is almost exclusively supratentorial in location. We report an extremely unusual presentation of a densely calcified posterior fossa astroblastoma with disseminated spinal and supratentorial metastasis. The mass exhibited neoplastic bone formation, which has not been reported, although calcifications are commonly seen in astroblastomas. A companion case of a low-grade astroblastoma that demonstrated classic histologic features but nonspecific and atypical imaging findings is also included. These cases expand the imaging and pathologic spectrum of this controversial tumor that shows highly variable biologic behavior and is difficult to distinguish from ependymoma. PMID:18958463

  13. The cruel and unusual phenomenology of solitary confinement

    PubMed Central

    Gallagher, Shaun

    2014-01-01

    What happens when subjects are deprived of intersubjective contact? This paper looks closely at the phenomenology and psychology of one example of that deprivation: solitary confinement. It also puts the phenomenology and psychology of solitary confinement to use in the legal context. Not only is there no consensus on whether solitary confinement is a “cruel and unusual punishment,” there is no consensus on the definition of the term “cruel” in the use of that legal phrase. I argue that we can find a moral consensus on the meaning of “cruelty” by looking specifically at the phenomenology and psychology of solitary confinement. PMID:24971072

  14. Using Helical CT to Predict Stone Fragility in Shock Wave Lithotripsy (SWL)

    SciTech Connect

    Williams, James C. Jr.; Zarse, Chad A.; Jackson, Molly E.; McAteer, James A. [Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN 46202 (United States); Lingeman, James E. [Methodist Hospital Institute for Kidney Stone Disease, 1801 North Senate Boulevard, Suite 220, Indianapolis, Indiana 46202 (United States)

    2007-04-05

    Great variability exists in the response of urinary stones to SWL, and this is true even for stones composed of the same mineral. Efforts have been made to predict stone fragility to shock waves using computed tomography (CT) patient images, but most work to date has focused on the use of stone CT number (i.e., Hounsfield units). This is an easy number to measure on a patient stone, but its value depends on a number of factors, including the relationship of the size of the stone to me resolution (i.e., the slicewidth) of the CT scan. Studies that have shown a relationship between stone CT number and failure in SWL are reviewed, and all are shown to suffer from error due to stone size, which was not accounted for in the use of Hounsfield unit values. Preliminary data are then presented for a study of calcium oxalate monohydrate (COM) stones, in which stone structure-rather than simple CT number values-is shown to correlate with fragility to shock waves. COM stones that were observed to have structure by micro CT (e.g., voids, apatite regions, unusual shapes) broke to completion in about half the number of shock waves required for COM stones that were observed to be homogeneous in structure by CT. This result suggests another direction for the use of CT in predicting success of SWL: the use of CT to view stone structure, rather than simply measuring stone CT number. Viewing stone structure by CT requires the use of different viewing windows than those typically used for examining patient scans, but much research to date indicates that stone structure can be observed in the clinical setting. Future clinical studies will need to be done to verify the relationship between stone structure observed by CT and stone fragility in SWL.

  15. Using Helical CT to Predict Stone Fragility in Shock Wave Lithotripsy (SWL)

    NASA Astrophysics Data System (ADS)

    Williams, James C.; Zarse, Chad A.; Jackson, Molly E.; Lingeman, James E.; McAteer, James A.

    2007-04-01

    Great variability exists in the response of urinary stones to SWL, and this is true even for stones composed of the same mineral. Efforts have been made to predict stone fragility to shock waves using computed tomography (CT) patient images, but most work to date has focused on the use of stone CT number (i.e., Hounsfield units). This is an easy number to measure on a patient stone, but its value depends on a number of factors, including the relationship of the size of the stone to me resolution (i.e., the slicewidth) of the CT scan. Studies that have shown a relationship between stone CT number and failure in SWL are reviewed, and all are shown to suffer from error due to stone size, which was not accounted for in the use of Hounsfield unit values. Preliminary data are then presented for a study of calcium oxalate monohydrate (COM) stones, in which stone structure—rather than simple CT number values—is shown to correlate with fragility to shock waves. COM stones that were observed to have structure by micro CT (e.g., voids, apatite regions, unusual shapes) broke to completion in about half the number of shock waves required for COM stones that were observed to be homogeneous in structure by CT. This result suggests another direction for the use of CT in predicting success of SWL: the use of CT to view stone structure, rather than simply measuring stone CT number. Viewing stone structure by CT requires the use of different viewing windows than those typically used for examining patient scans, but much research to date indicates that stone structure can be observed in the clinical setting. Future clinical studies will need to be done to verify the relationship between stone structure observed by CT and stone fragility in SWL.

  16. Soft tissue imaging with photon counting spectroscopic CT.

    PubMed

    Shikhaliev, Polad M

    2015-03-21

    The purpose of this work was experimental investigation of photon counting spectroscopic CT (PCS-CT) imaging of anatomical soft tissue with clinically relevant size. The imaging experiments were performed using a spectroscopic CT system based on CdZnTe photon counting detector with two rows of pixels, 256 pixels in each row, 1? × ?1?mm(2)?pixel size, and 25.6?cm detector length. The detector could split the x-ray energy spectrum to 5 regions (energy bins), and acquire 5 multi-energy (spectroscopic) CT images in a single CT scan. A sample of round shaped anatomical soft tissue of 14?cm diameter including lean and fat was used for imaging. To avoid the negative effect of anatomical noise on quantitative analysis, a spectroscopic CT phantom with tissue equivalent solid materials was used. The images were acquired at 60, 90, and 120?kVp tube voltages, and spectroscopic image series were acquired with 3 and 5 energy bins. Spectroscopic CT numbers were introduced and used to evaluate an energy selective image series. The anatomical soft tissue with 14?cm diameter was visualized with good quality and without substantial artifacts by the photon counting spectroscopic CT system. The effects of the energy bin crosstalk on spectroscopic CT numbers were quantified and analyzed. The single and double slice PCS-CT images were acquired and compared. Several new findings were observed, including the effect of soft tissue non-uniformity on image artifacts, unique status of highest energy bin, and material dependent visualization in spectroscopic image series. Fat-lean decomposition was performed using dual energy subtraction and threshold segmentation methods, and compared. Using K-edge filtered x-rays improved fat-lean decomposition as compared to conventional x-rays. Several new and important aspects of the PCS-CT were investigated. These include imaging soft tissue with clinically relevant size, single- and double-slice PCS-CT imaging, using spectroscopic CT numbers to quantify multi-energy PCS-CT images, application of K-edge filtered x-rays for improved soft tissue decomposition, and several others. The study suggests that the presented PCS-CT technology meets the requirements of a particular clinical application, i.e. dedicated breast CT. PMID:25739788

  17. Learning optimal eye movements to unusual faces

    PubMed Central

    Peterson, Matthew F.; Eckstein, Miguel P.

    2014-01-01

    Eye movements, which guide the fovea’s high resolution and computational power to relevant areas of the visual scene, are integral to efficient, successful completion of many visual tasks. How humans modify their eye movements through experience with their perceptual environments, and its functional role in learning new tasks, has not been fully investigated. Here, we used a face identification task where only the mouth discriminated exemplars to assess if, how, and when eye movement modulation may mediate learning. By interleaving trials of unconstrained eye movements with trials of forced fixation, we attempted to separate the contributions of eye movements and covert mechanisms to performance improvements. Without instruction, a majority of observers substantially increased accuracy and learned to direct their initial eye movements towards the optimal fixation point. The proximity of an observer’s default face identification eye movement behavior to the new optimal fixation point and the observer’s peripheral processing ability were predictive of performance gains and eye movement learning. After practice in a subsequent condition in which observers were directed to fixate different locations along the face, including the relevant mouth region, all observers learned to make eye movements to the optimal fixation point. In this fully learned state, augmented fixation strategy accounted for 43% of total efficiency improvements while covert mechanisms accounted for the remaining 57%. The findings suggest a critical role for eye movement planning to perceptual learning, and elucidate factors that can predict when and how well an observer can learn a new task with unusual exemplars. PMID:24291712

  18. Aberrant radial-ulnar nerve communication in the upper arm presenting as an unusual radial nerve palsy: a case report.

    PubMed

    Lombardo, Daniel J; Buzas, David; Siegel, Geoffrey; Afsari, Alan

    2015-05-01

    An unusual communication between the radial and ulnar nerves was observed during repair of a fracture of the humerus in an adult patient who presented with unusual physical exam findings. The patient had loss of radial and ulnar nerve motor function, as well as decreased sensation in both nerve distributions. Radial nerve injury following fracture of the humerus is a common condition, and anatomic variations are therefore of importance to clinicians. Communications between branches of the brachial plexus are also not uncommon findings; however there is very little mention of communication between the radial and ulnar nerves in the literature. An appreciation of unusual nerve anatomy is important in explaining unusual finding in patients. PMID:25481257

  19. Finding trails

    Microsoft Academic Search

    Scott Morris; Kobus Barnard

    2008-01-01

    We present a statistical learning approach for finding recreational trails in aerial images. While the problem of recognizing relatively straight and well defined roadways in digital images has been well studied in the literature, the more difficult problem of extracting trails has received no attention. However, trails and rough roads are less likely to be adequately mapped, and change more

  20. An unusual cause of a pain in the neck: pseudoaneurysm from tuberculous lymphadenitis.

    PubMed

    Kennedy, B; Curran, D R; Brady, A; O'Connor, T M

    2012-01-01

    A pseudoaneurysm is a haematoma which is surrounded by connective tissue and communicates with the lumen of a ruptured blood vessel. It has no true defined capsule. We describe a case of tuberculous pseudoaneurysm. This is a rare complication of tuberculosis. The clinical presentation of these lesions is highly variable. Definitive diagnosis should consist of contrast-enhanced CT and arteriography. Treatment should include repair of the arterial wall by surgery, endovascular stent-graft insertion, or embolization followed by a full course of antituberculous chemotherapy. Our case is highly unusual in that the pseudoaneurysm arose from the subclavian vasculature in a patient with extrapulmonary tuberculosis only. PMID:22969808

  1. Hepatic Portal Venous Gas: An Unusual Complication Following Upper Endoscopy and Dilation

    PubMed Central

    Seeger, Kristina

    2014-01-01

    Hepatic portal venous gas (HPVG), a rare condition in which gas accumulates in the portal venous circulation, is often associated with a significant underlying pathology, such as intestinal ischemia, sepsis, and trauma. HPVG after endoscopy or dilation is an unusual complication. We report a case of HPVG following upper endoscopy and dilation for an esophageal stricture in a 34-year-old patient with eosinophilic esophagitis (EoE). The patient was treated conservatively, and his symptoms resolved. Follow-up computed tomography (CT) scan showed resolution of HPVG. This case highlights a rare and potentially ominous complication of upper endoscopy and dilation and underscores the role of conservative management.

  2. Acute subarachnoid hemorrhage. An unusual clinical presentation of cerebral venous sinus thrombosis.

    PubMed

    Hassan, Ali; Ahmad, Bakhtiar; Ahmed, Zahoor; Al-Quliti, Khalid W

    2015-01-01

    Ruptured cerebral aneurysm is the most common cause of spontaneous subarachnoid hemorrhage (SAH). Rarely cerebral venous sinus thrombosis (CVST) may present initially as acute SAH, and clinically mimics aneurysmal bleed. We report 2 cases of CVST who presented with severe headache associated with neck pain and focal seizures. Non-contrast brain CT showed SAH, involving the sulci of the convexity of hemisphere (cSAH) without involving the basal cisterns. Both patients received treatment with anticoagulants and improved. Awareness of this unusual presentation of CVST is important for early diagnosis and treatment. The purpose of this paper is to emphasize the inclusion of vascular neuroimaging like MRI with venography or CT venography in the diagnostic workup of SAH, especially in a patient with strong clinical suspicion of CVST or in a patient where neuroimaging showed cSAH. PMID:25630784

  3. An unusual case of "dyadic-death" with a single gunshot.

    PubMed

    Viero, Alessia; Giraudo, Chiara; Cecchetto, Giovanni; Muscovich, Cristina; Favretto, Donata; Puglisi, Massimo; Fais, Paolo; Viel, Guido

    2014-11-01

    The terms "dyadic death" or "murder-suicide" refer to an incident where an individual commits homicide and then takes his or her own life. These events are generally committed by men within the family network, using firearms or sharp force instruments, and make up a relatively small proportion of homicides overall. Herein, we present the application of post-mortem multislice computed tomography (CT) and micro-CT analysis to an unusual case of dyadic death, where a 38-year-old man fired a single gunshot to his own right temple, killing himself and his 50-year-old wife, lying on the bed beside him. The integration of radiological, autoptic and histological data allowed us to reconstruct the trajectory of the gunshot, the most probable dynamics of the event, and to classify the incident as a "suicide-homicide", because the female victim died a few minutes later than her husband and murderer. PMID:25194714

  4. FDG-PET/CT Imaging for Staging and Target Volume Delineation in Preoperative Conformal Radiotherapy of Rectal Cancer

    SciTech Connect

    Bassi, Maria Chiara; Turri, Lucia [Department of Radiotherapy, University of Piemonte Orientale, Novara (Italy); Sacchetti, Gianmauro [Department of Nuclear Medicine, University of Piemonte Orientale, Novara (Italy); Loi, Gianfranco; Cannillo, Barbara [Department of Medical Physics, Hospital Maggiore della Carita, Novara (Italy); La Mattina, Pierdaniele [Department of Radiotherapy, University of Piemonte Orientale, Novara (Italy); Brambilla, Marco [Department of Medical Physics, Hospital Maggiore della Carita, Novara (Italy); Inglese, Eugenio [Department of Nuclear Medicine, University of Piemonte Orientale, Novara (Italy); Krengli, Marco [Department of Radiotherapy, University of Piemonte Orientale, Novara (Italy)], E-mail: krengli@med.unipmn.it

    2008-04-01

    Purpose: To investigate the potential impact of using {sup 18}F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) on staging and target volume delineation for patients affected by rectal cancer and candidates for preoperative conformal radiotherapy. Methods and Materials: Twenty-five patients diagnosed with rectal cancer T3-4 N0-1 M0-1 and candidates for preoperative radiotherapy underwent PET/CT simulation after injection of 5.18 MBq/kg of FDG. Clinical stage was reassessed on the basis of FDG-PET/CT findings. The gross tumor volume (GTV) and the clinical target volume (CTV) were delineated first on CT and then on PET/CT images. The PET/CT-GTV and PET/CT-CTV were analyzed and compared with CT-GTV and CT-CTV, respectively. Results: In 4 of 25 cases (24%), PET/CT affected tumor staging or the treatment purpose. In 3 of 25 cases (12%) staged N0 M0, PET/CT showed FDG uptake in regional lymph nodes and in a case also in the liver. In a patient with a single liver metastasis PET/CT detected multiple lesions, changing the treatment intent from curative to palliative. The PET/CT-GTV and PET/CT-CTV were significantly greater than the CT-GTV (p = 0.00013) and CT-CTV (p = 0.00002), respectively. The mean difference between PET/CT-GTV and CT-GTV was 25.4% and between PET/CT-CTV and CT-CTV was 4.1%. Conclusions: Imaging with PET/CT for preoperative radiotherapy of rectal cancer may lead to a change in staging and target volume delineation. Stage variation was observed in 12% of cases and a change of treatment intent in 4%. The GTV and CTV changed significantly, with a mean increase in size of 25% and 4%, respectively.

  5. Finding Colors

    NSDL National Science Digital Library

    2014-08-27

    In this chemistry challenge, learners combine acids and bases in a universal indicator to create five different colors. Using vinegar, washing soda, and Bogen universal indicator, the goal is to find combinations that create red, orange, yellow, green, and blue solutions. Background information explains a little about how acids and bases interact to affect the pH of a solution, and how the indicator changes color based on the pH. Safety notes are included.

  6. Factor Findings

    NSDL National Science Digital Library

    Jamie Piecora

    2000-01-01

    In this lesson, students first create factor posters for a variety of different numbers that will be displayed in the classroom to be utilized as a resource throughout the school year. They make discoveries about factors using color tiles, represent their discoveries using graph paper, and display their information on poster board as find factors of an assigned number. The plan includes a list of materials, questions, assessment options, and extensions.

  7. Methanol poisoning: characteristic MRI findings.

    PubMed

    Jain, Nirdesh; Himanshu, Dandu; Verma, Shailendra Prasad; Parihar, Anit

    2013-01-01

    Acute methanol intoxication is not an unusual poisoning. It can have serious neurological sequelae. We emphasize how neuroimaging can help in distinguishing methanol poisoning from other causes of acute unconsciousness in alcoholic patients such as hypoglycemic brain damage and carbon monoxide poisoning or head injury, which are frequently observed in alcoholic patients and are also responsible for altered sensorium. The most important findings in MR brain imaging in methanol poisoning have been bilateral putaminal hemorrhagic necrosis. Other less common findings are subcortical and deep white matter lesions, cerebral and cerebellar cortical lesions, and midbrain lesions, cerebral and intraventricular hemorrhage, and even enhancement of necrotic lesions, we found almost the entire spectrum of MRI findings in this patient with methanol poisoning. Neurological sequelae can entail the course and prognosis in methanol poisoning. The patient died because of ventilator-associated pneumonia that developed in the course of prolonged hospitalization. PMID:22634487

  8. Cholesterol granuloma of the petrous apex: CT diagnosis

    SciTech Connect

    Lo, W.W.M.; Solti-Bohman, L.G.; Brackmann, D.E.; Gruskin, P.

    1984-12-01

    Cholesterol granuloma of the petrous apex is a readily recognizable and treatable entity that is more common than previously realized. Cholesterol granuloma grows slowly in the petrous apex as a mass lesion until it produces hearing loss, tinnitus, vertigo, and facial twitching. Twelve cases of cholesterol granuloma of the petrous apex are illustrated; ten of these analyzed in detail, especially with respect to CT findings. A sharply and smoothly marginated expansile lesion in the petrous apex, isodense with plain and nonenhancing on CT, is in all probability a cholesterol granuloma. Preoperative recognition by CT is important for planning proper treatment.

  9. On the unusual characteristics of the diamonds from Letšeng-la-Terae kimberlites, Lesotho

    NASA Astrophysics Data System (ADS)

    Bowen, Debbie C.; Ferraris, Ray D.; Palmer, Claire E.; Ward, John D.

    2009-11-01

    The Letšeng-la-Terae kimberlites are situated 3100 m above sea level in the Maloti Mountains of Lesotho, southern Africa. The principal economic bodies are two Late Cretaceous, low grade, 1-3.5 carats/hundred ton (cpht), kimberlite pipes that host high-value diamonds realising US 2000-2500/carat (/ct) in 2008 terms. Locally, the larger kimberlite body is referred to as the Main Pipe (17.2 ha) and the smaller one is called the Satellite Pipe (5.2 ha). These pipes, and their associated eluvial and proximal alluvial deposits, are renowned for yielding large, "D" colour, gem quality diamonds, including + 100 carat (ct) stones. Earlier artisanal effort (1959-1977) and formal mining (1977-1982) produced 335,000 carats (cts), including the 601 ct Lesotho Brown in 1968. In 2003, Letšeng Diamonds Limited re-commenced mining operations and had produced 265,000 cts by the end of July 2008, including 24 + 100 ct diamonds, the largest of which was the 603 ct Lesotho Promise. We report here on the unusual characteristics of the Letšeng diamond population that include: 75% gem quality that is more commonly associated with alluvial diamond deposits, large average stone size of ca. 1 carat/stone (ct/stn) that is also more typical of certain alluvial diamond placers, high-yielding, rounded to flattened irregular, resorbed dodecahedral shapes (Main Pipe 67% and Satellite Pipe 87%) with subordinate dodecahedral macle (Main Pipe 32% and Satellite Pipe 12%) and broken (ca. 1%) forms. In both pipes the octahedral component is virtually absent (< 0.1%), economically favourable colour mix (ca. 33% white colour diamonds in both pipes), abundance of nitrogen-free, "D" colour, Type IIa diamonds that dominate the internationally recognised "special" stone size fraction which covers all diamonds larger than + 10.8 cts (Main Pipe 32% and Satellite Pipe 51%). During 2008, these larger, "special" diamonds commanded prices in excess of US 15,000/ct, contributing ca. 75% of the revenue generated by the Letšeng mine. Furthermore, of the 24 + 100 ct diamonds recovered between November 2003 and July 2008, 18 (75%) were Type IIa "D" colour diamonds that also fetched prices mostly in excess of US 25,000/ct. Therefore the Type IIa diamonds boost significantly the revenue per unit measure (in this case, the US$/ton) of the Letšeng-la-Terae pipes, making these low grade kimberlites economic to mine.

  10. Less common CT features of medulloblastoma

    SciTech Connect

    Zee, C.S (Univ. of Southern California School of Medicine, Los Angeles); Segall, H.D.; Miller, C.; Ahmad, J.; McComb, J.G.; Han, J.S.; Park, S.H.

    1982-07-01

    While many medulloblastomas have characteristic features on computed tomography (CT), a significant number have atypical features, including a cystic or necrotic component, calcification, hemorrhage, lack of contrast enhancement, and eccentric location, and/or direct supratentorial extension. Of 30 consecutive untreated cases reviewed by the authors, 14 (47%) had such findings. Failure to make the proper diagnosis will result in some cases if these features are not recognized as possible signs of medulloblastoma.

  11. Pitfalls in PET/CT imaging

    NASA Astrophysics Data System (ADS)

    Rondogianni, Ph; Papathanasiou, N.; Giannopoulou, Ch

    2011-09-01

    PET with 2-[fluorine 18] fluoro-2-deoxy-d-glucose (FDG), has been a clinical tool for the evaluation of various cancers providing valuable metabolic information clinically helpful in the diagnosis, initial staging, therapy monitoring and restaging. However, FDG is not specific for neoplastic processes. Unless anatomic correlation is available to delineate normal structures, pathologic sites of FDG accumulation can easily be confused with normal physiological uptake, leading to false-positive or false-negative findings. Coregistration of PET scans (functional and morphologic information) with computed tomographic (CT) scans (anatomic information) using a combined PET-CT scanner improves the overall sensitivity and specificity of information provided by PET or CT alone. In this paper, we discuss the probable causes of false negative images and pitfalls due to technical reasons, inflammatory processes or benign lesions as well as the utility of PET-CT in differentiating malignant from inflammatory and benign processes, since in some cases such differentiation cannot be made, with certainty, using FDG PET alone.

  12. Testing Peer Effects among College Students: Evidence from an Unusual Admission Policy Change in China

    ERIC Educational Resources Information Center

    Lu, Fangwen

    2014-01-01

    This paper studies a natural experiment due to an unusual change in the college admission policy at a Chinese university, which brought a large number of low-score students into several academic departments in the university. Exploiting large variations in peer characteristics and strong interactions among peer groups, the analysis finds that…

  13. Leukaemic infiltration of gall bladder – unusual presentation of occult chronic lymphocytic leukaemia

    PubMed Central

    Rao, VSR; Watkins, R; Kaleem, AZ; Cooke, J; Wedgwood, K

    2011-01-01

    Extramedullary involvement in early stage chronic lymphocytic leukaemia (CLL) is rare. We report the first case of an incidental finding of gall bladder infiltration in a patient who underwent a cholecystectomy for gallstone pancreatitis with no preceding history of CLL. This case reiterates the importance of subjecting even routine cholecystectomy specimens for histopathology examination in the context of this unusual presentation. PMID:24950545

  14. Wuchereria bancrofti microfilariae in the dentigerous cystic fluid: an unusual presentation.

    PubMed

    Agrawal, K; Mekhala, A; Chitra, S; Narasimhan, R; Ratnakar, C

    1998-08-01

    An unexpected and unusual presence of Wuchereria bancrofti microfilariae in the cystic fluid of a maxillary dentigerous cyst in an 8-year-old boy is being reported for the first time. This was an incidental finding during routine fine-needle aspiration cytological examination. PMID:9718157

  15. Pancreatic ductal adenocarcinoma: diagnosis and staging with dynamic CT.

    PubMed

    Freeny, P C; Marks, W M; Ryan, J A; Traverso, L W

    1988-01-01

    The authors assessed the accuracy of dynamic computed tomography (CT) in diagnosis and staging of ductal adenocarcinoma of the pancreas and analyzed the survival rates of patients with resectable and unresectable tumors. A correct diagnosis based on CT findings was made in 159 of 174 patients (91%) with 13 false-positive (8%) and two false-negative diagnoses (1%). The 13 false-positive diagnoses highlight the need for confirmation of diagnosis with biopsy. The accuracy of staging with CT was compared with that of angiography (42 patients) and surgery (51 patients). CT was more accurate than angiography in demonstrating tumor involvement of major peripancreatic vessels. Staging criteria were reliable: No unresectable tumors based on CT findings were found to be resectable during surgery (42 patients), while only three of nine resectable tumors based on CT findings were found to be unresectable. Thus, no tumors were incorrectly staged, which would potentially deny surgery for a patient. The average survival rate after resection was 14 months, while the survival rates after palliative (biliary or gastrointestinal bypass) or no treatment were 8 months and 5 months, respectively. PMID:2827228

  16. CT number definition

    NASA Astrophysics Data System (ADS)

    Bryant, J. A.; Drage, N. A.; Richmond, S.

    2012-04-01

    The accuracy of CT number plots has been found lacking in several medical applications. This is of concern since the ability to compare and evaluate results on a reproducible and standard basis is essential to long term development. Apart from the technical limitations arising from the CT scanner and the data treatment, there are fundamental issues with the definition of the Hounsfield number, namely the absence of a standard photon energy and the need to specify the attenuation mechanism for standard measurements. This paper presents calculations to demonstrate the shortcomings of the present definition with a brief discussion. The remedy is straightforward, but probably of long duration as it would require an international agreement.

  17. Pericardiacophrenic shunt: imaging finding of rare splenosystemic collateral. Case report.

    PubMed

    Kutlu, Ramazan; Alkan, Alpay; Sigirci, Ahmet

    2006-08-01

    Portosystemic collaterals are the natural consequence of portal hypertension. These collaterals can occur anywhere in the gastrointestinal tract. Apart from the usual sites, they can develop in some unusual and rare locations. In this report, imaging findings of an unusual venous collateral pathway between spleen and left subclavian vein in a 30-year-old female patient with cirrhosis and portal hypertension are presented. PMID:16628381

  18. Lateral displacement of the right kidney by the colon: an anatomic variation demonstrated by CT

    SciTech Connect

    Silverman, P.M.; Kelvin, F.M.; Korobkin, M.

    1983-02-01

    Lateral displacement of the kidney on a urogram can be caused by a variety of retroperitoneal abnormalities, including enlarged lymph nodes, primary or metastatic neoplasm, aortic aneurysm, hematoma, abscess, or even benign accumulations of fat. CT commonly is used to evaluate the cause of renal displacement and often suggests the correct etiology. An unusual case is reported in which CT demonstrated that lateral displacement of the right kidney was caused by insinuation of an otherwise normal right colon between the kidney and the right psoas muscle. The authors are not aware of any previous report of this benign anatomic variant.

  19. [The Adamant, an unusual care centre].

    PubMed

    Khidichian, Frédéric

    2011-01-01

    The day care centre of the central Paris area has established itself in an unusual location--a 650 m2 floating building moored on the right bank of the Seine. Patients and caregivers were involved in the design of this original and ecological care centre, which places the emphasis on comfort and safety. PMID:21972746

  20. 5, 1040910420, 2005 Unusual high solar

    E-print Network

    Paris-Sud XI, Université de

    the tropics. The resultant increase in UV-radiation is of particular significance for human health. We want to point out the risks for human health by exeACPD 5, 10409­10420, 2005 Unusual high solar ultraviolet radiation in central Europe C. Stick et al

  1. An unusual oviraptorosaurian dinosaur from China

    Microsoft Academic Search

    Xing Xu; Yen-Nien Cheng; Xiao-Lin Wang; Chun-Hsiang Chang

    2002-01-01

    Oviraptorosaurians are an unusual group of theropod dinosaurs, with highly specialized skulls. Here we report a new oviraptorosaurian, Incisivosaurus gauthieri, gen. et sp. nov., from the lowest part of the Lower Cretaceous Yixian Formation of China. This oviraptorosaurian displays a number of characters closer to more typical theropods, such as a low skull and toothed jaws, thus greatly reducing the

  2. Performance of integrated FDG PET\\/contrast-enhanced CT in the diagnosis of recurrent colorectal cancer: Comparison with integrated FDG PET\\/non-contrast-enhanced CT and enhanced CT

    Microsoft Academic Search

    Kazuhiro Kitajima; Koji Murakami; Erena Yamasaki; Yasushi Domeki; Masahiro Tsubaki; Masakatsu Sunagawa; Yasushi Kaji; Narufumi Suganuma; Kazuro Sugimura

    2009-01-01

    Purpose  The aim of our study was to evaluate the accuracy of integrated positron emission tomography and computed tomography (PET\\/CT)\\u000a using 18F-fluorodeoxyglucose (FDG) with IV contrast for depiction of suspected recurrent colorectal cancer and to assess the impact\\u000a of PET\\/contrast-enhanced CT findings on clinical management compared with PET\\/non-contrast-enhanced CT and CT component.\\u000a \\u000a \\u000a \\u000a Methods  One hundred seventy patients previously treated for colorectal cancer

  3. CT and MR of the Brain in Glutaric Acidemia Type I: A Review of 59 Published Cases and a Report of 5 New Patients

    Microsoft Academic Search

    Jan Brismar; Pinar T. Ozand

    PURPOSE: To identify a pattern of findings on CT or MR of the brain in glutaric acidemia type I typical enough to permit a correct diagnosis.METHODS:Clinical history and findings and brain CT and MR results in 59 previously reported patients (MR in 12) and in 5 new patients (all examined with MR and 3 also with CT) were reviewed. RESULTS:

  4. CT number variations in micro CT imaging systems

    NASA Astrophysics Data System (ADS)

    Tu, Shu-Ju; Hsieh, Hui-Ling; Chao, Tsi-Chian

    2008-03-01

    CT numbers can be directly computed from the linear attenuation coefficients in the reconstructed CT images and are correlated to the electron densities of the chemical elements with specific atomic numbers. However, the computed CT numbers can be varied when different imaging parameters are used. Phantoms composed of clinically relevant and tissue-equivalent materials (lung, bone, muscle, and adipose) were scanned with a commercial circular-scanning micro CT imager. This imaging system is composed with a micro-focused x-ray tube and charged-coupled device (CCD) camera as the detector. The mean CT numbers and the corresponding standard deviations in terms of Hounsfield units were then computed from a pre-defined region of interest located within the reconstructed volumetric images. The variations of CT number were then identified from a series of imaging parameters. Those parameters include imaging acquisition modes (e.g., the metal filter used in the x-ray tube), reconstruction methods (e.g., Feldkamp and iterative algorithm), and post-image processing techniques (e.g., ring artifact, beam-hardening artifact, and smoothing processing). These variations of CT numbers are useful and important in tissue characterization, quantitative bone structure analysis, bone marrow density evaluation, and Monte Carlo dose calculations for the pilot small animal study when micro CT imaging systems are employed. Also these variations can be used as the quantification for the performance of the micro CT imaging systems.

  5. PET/CT AND RADIOIMMUNOTHERAPY OF PROSTATE CANCER

    PubMed Central

    Bouchelouche, Kirsten; Capala, Jacek; Oehr, Peter

    2009-01-01

    Purpose of review Traditional morphologically based imaging modalities are now being complemented by positron emission tomography (PET)/computerized tomography (CT) in prostate cancer. Metastatic prostate cancer is an attractive target for radioimmunotherapy (RIT) since no effective therapies are available. This review highlights the most important achievements within the last year in PET/CT and RIT of prostate cancer. Recent findings Conflicting results exist on the use of choline for detection of malignant disease in the prostate gland. The role of PET/CT in N-staging remains to be elucidated further. However, 18F-choline and 11C-choline PET/CT have been demonstrated to be useful for detection of recurrence. 18F-choline and 18F-fluoride PET/CT are useful for detection of bone metastases. Prostate tumor antigens may be used as targets for RIT. Prostate specific membrane antigen (PSMA) is currently under focus of a number of diagnostic and therapeutic strategies. J591, a monoclonal antibody, that targets the extracellular domain of PSMA, shows promising results. HER2 receptors may also have a potential as target for PET/CT imaging and RIT of advanced prostate cancer. Summary PET/CT in prostate cancer has proven to play a significant role, in particular for detection of prostate cancer recurrence and bone metastases. Radioimmunotherapy of metastatic prostate cancer warrant further investigations. PMID:19535981

  6. Finding Your Way University Hospital East

    E-print Network

    Hawthorne Ave Phale D. Hale Dr P P P WALLACE AUDITORIUM ENTRANCE EMERGENCY Physician Entrance Tower Talbot Elevators Stairs Mens Restroom Womens Restroom RadiologyEmergency Entrance Second Floor #12;Finding Your Way- Floor 4 EEG/EMG Check In at West Registration Talbot - Floor 4 Education Ct Tower 16 Emergency Enter

  7. 48 CFR 432.114 - Unusual contract financing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...2011-10-01 false Unusual contract financing. 432.114...Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial...Financing 432.114 Unusual contract financing. The HCA...

  8. Unusual fan shaped ossification in a female fetus with radiological features of boomerang dysplasia.

    PubMed

    Odent, S; Loget, P; Le Marec, B; Delezoïde, A L; Maroteaux, P

    1999-04-01

    We report on a female fetus of 24 weeks whose clinical and radiological findings were compatible with boomerang dysplasia (BD). However, histopathology was unusual with a lateral fan shaped diaphyseal ossification. This has never been described either in typical atelosteogenesis I (AT-I) or in BD. The purpose of this report is to find out if this condition is a separate lethal bone dysplasia or another histological feature of the nosological group of AT-I and BD. PMID:10227404

  9. Coronary CT Angiography: Native Vessels

    Microsoft Academic Search

    Stephan Achenbach

    \\u000a Visualization of the coronary arteries has been the major focus of cardiac CT in the past years. Noninvasive “coronary CT\\u000a angiography” has tremendous clinical potential for detecting or ruling out coronary artery stenoses in selected patients.\\u000a In addition, imaging of coronary atherosclerotic plaque may play a potential role in risk stratification. However, spatial\\u000a resolution and temporal resolution of CT imaging,

  10. Comparison of CT head interpretation between emergency physicians and neuroradiologists.

    PubMed

    Al-Reesi, Abdullah; Stiell, Ian G; Al-Zadjali, Nabil; Cwinn, A Adam

    2010-10-01

    Cranial computed tomography (CT) of the head is widely used in the emergency department 24 h a day. We compared the accuracy of CT head interpretation between staff emergency physicians (EPs) and neuroradiologists. We conducted a health records review of patients who required head CT in the emergency department. Two independent reviewers rated disagreement as clinically normal, significant, or clinically insignificant findings using published definition criteria. We calculated concordance and prepared descriptive and kappa statistics with 95% confidence intervals using SAS 9.1 software. We included 442 for this study. CT heads were classified as: normal or nonacute 81.5% (360 cases), insignificant 3.8% (17 cases), and significant 14.7% (65 cases). The weighted kappa for agreement was 0.83 (95% confidence interval 0.76-0.90). None of these patients had adverse outcomes related to EP misinterpretation of the CT head. In conclusion, clinically important findings on CT head are not commonly missed by our EPs and patients rarely have inappropriate disposition. PMID:20154626

  11. CT dose reduction in practice.

    PubMed

    Callahan, Michael J

    2011-09-01

    Greater than 10% of diagnostic imaging studies performed in developed countries are CT examinations. In the United States, as many as 60 million CT studies are performed each year, up to 7 million of which are performed in pediatric patients. In the spirit of the ALARA principle, both adult and pediatric radiologists should strive to decrease pediatric radiation exposure whenever possible. This can be achieved by utilizing imaging studies that do not require the use of ionizing radiation, thus decreasing the number of CT studies performed. If a CT study is indicated, the delivered dose should be optimized to use the lowest possible dose level while still answering the clinical question. PMID:21847727

  12. Chronic osteomyelitis examined by CT

    SciTech Connect

    Wing, V.W.; Jeffrey, R.B. Jr.; Federle, M.P.; Helms, C.A.; Trafton, P.

    1985-01-01

    CT examination of 25 patients who had acute exacerbations of chronic osteomyelitis allowed for the correct identification of single or multiple sequestra in 14 surgical patients. Plain radiographs were equivocal for sequestra in seven of these patients, because the sequestra were too small or because diffuse bony sclerosis was present. CT also demonstrated a foreign body and five soft tissue abscesses not suspected on the basis of plain radiographs. CT studies, which helped guide the operative approach, were also useful in treating those patients whose plain radiographs were positive for sequestra. The authors review the potential role of CT in evaluating patients with chronic osteomyelitis.

  13. Cardiac Computed Tomography (Multidetector CT, or MDCT)

    MedlinePLUS

    Cardiac Computed Tomography (Multidetector CT, or MDCT) Updated:May 18,2015 What is Computerized Tomography (CT)? CT is a noninvasive test that uses X-rays to make pictures of your heart. Modern CT scanners (multidetector CT, or MDCT) work very fast ...

  14. CT Scan (CAT Scan)

    NSDL National Science Digital Library

    This patient education program explains the benefits and risks of Computed Axial Tomography, CAT scan or CT scan, and describes the procedure for the test. This is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute. NOTE: The tutorial requires a special Flash plug-in, version 4 or above. If you do not have Flash, you will be prompted to obtain a free download of the software before you start the tutorial. You will also need an Acrobat Reader, available as a free download, in order to view the Reference Summary.

  15. Detection and quantification of the parenchymal abnormalities in emphysema using pulmo-CT

    Microsoft Academic Search

    Osman Temizoz; Omer Etlik; Mehmet Emin Sakarya; Kursat Uzun; Halil Arslan; Mustafa Harman; Mustafa Kemal Demir

    2007-01-01

    We aimed to determine the degree and extent of parenchymal abnormalities on pulmo-CT in patients with emphysema. The study group consisted of 29 patients (18 male, 11 female; mean age 57.9±13). The diagnosis was based on clinical symptoms, pulmonary function tests (PFT) values, and chest CT findings. All of the patients CT scans were obtained during suspended deep inspiration from

  16. Diagnostic accuracy of preoperative CT scanning of pituitary prolactinomas.

    PubMed

    Marcovitz, S; Wee, R; Chan, J; Hardy, J

    1988-01-01

    Between 1980 and 1985, 102 patients (84 women and 18 men) who had coronal CT scans of the sella turcica for suspected prolactin adenoma underwent transsphenoidal exploration. The CT examinations were performed with a fourth-generation EMI scanner (CT 7070), and reports of the preoperative CT examinations were compared with the findings at transsphenoidal exploration. The same neurosurgeon performed all the operations. In 97 patients distinct adenomas were found at surgery, among which were 36 macroadenomas (diameter larger than 10 mm) and 62 microadenomas (one patient had two coexisting microadenomas). All macroadenomas were identified correctly on the preoperative CT scans. Preoperative CT scans correctly localized 58 microadenomas in 57 of 62 patients, for a sensitivity rate of 91.9%; this included correct localization in four patients with recurrent microprolactinomas and in the one patient with two coexisting adenomas. Three patients in whom the adenomas were found in a location other than that reported on the preoperative CT scan were considered to have false-negative scans for the purpose of statistical calculations; two other false negatives occurred in patients whose scans had been interpreted as entirely normal and who were subsequently found to have adenomas at operation. Four patients had negative surgical explorations and the preoperative CT scan was correct in one, for a specificity of 25%. The overall accuracy rate was 92.1% for the entire group of patients and 87.7% for the subgroup of microadenomas. In our experience, coronal CT scanning has high diagnostic accuracy in patients with pituitary prolactinomas. PMID:3124565

  17. Rising utilization of CT in adult fall patients.

    PubMed

    Brinjikji, Waleed; Kallmes, David F; Cloft, Harry J

    2015-03-01

    OBJECTIVE. Falls are a common cause of emergency department (ED) visits in the United States. We evaluated trends in CT utilization for adult fall patients in the United States from 2001 to 2010. MATERIALS AND METHODS. Using the National Hospital Ambulatory Medical Care Survey, we identified all visits from 2001 to 2010 of adult patients presenting to EDs after falls. This database surveys approximately 500 EDs annually for 4 weeks, providing national estimates on ED resource utilization and outcomes. We studied trends in CT utilization and proportion of visits with life-threatening conditions (intracranial hemorrhage, organ laceration, axial skeletal fractures) after falls. We also studied the association between CT utilization rates and demographic characteristics and admission status. RESULTS. A total of 22,166 unweighted observations representing 73,241,368 visits were identified. The proportion of adult fall patient visits during which CT was performed increased from 11.4% in 2001 to 28.0% in 2010 (p < 0.0001), whereas the proportion of adult fall visits with life-threatening conditions increased from 5.7% to 8.2% (p < 0.0001). On adjusted analysis (adjusting for life-threatening condition and demographic variables), each successive year was independently associated with CT utilization (odds ratio, 1.21 [95% CI, 1.21-1.21]). The odds of CT utilization in 2010 compared with 2001 were 2.62 (95% CI, 2.61-2.62). CONCLUSION. There was a 2.5-fold increase in CT utilization among adult fall patient visits from 2001 to 2010. When demographic and clinical variables were controlled for, increasing year was independently associated with CT utilization. These findings suggest that CT may be overutilized among adult fall patients. PMID:25714285

  18. AMP-activated protein kinase phosphorylates CtBP1 and down-regulates its activity

    SciTech Connect

    Kim, Jae-Hwan; Choi, Soo-Youn; Kang, Byung-Hee; Lee, Soon-Min [National Creative Research Center for Epigenome Reprogramming Network, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 110-799 (Korea, Republic of)] [National Creative Research Center for Epigenome Reprogramming Network, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 110-799 (Korea, Republic of); Park, Hyung Soon; Kang, Gum-Yong; Bang, Joo Young [Center for Biomedical Mass Spectrometry, Diatech Korea Co., Ltd., Seoul (Korea, Republic of)] [Center for Biomedical Mass Spectrometry, Diatech Korea Co., Ltd., Seoul (Korea, Republic of); Cho, Eun-Jung [National Research Laboratory for Chromatin Dynamics, College of Pharmacy, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of)] [National Research Laboratory for Chromatin Dynamics, College of Pharmacy, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of); Youn, Hong-Duk, E-mail: hdyoun@snu.ac.kr [National Creative Research Center for Epigenome Reprogramming Network, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 110-799 (Korea, Republic of) [National Creative Research Center for Epigenome Reprogramming Network, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 110-799 (Korea, Republic of); WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence and Technology, Seoul National University, Seoul (Korea, Republic of)

    2013-02-01

    Highlights: ? AMPK phosphorylates CtBP1 on serine 158. ? AMPK-mediated phosphorylation of CtBP1 causes the ubiquitination and nuclear export of CtBP1. ? AMPK downregulates the CtBP1-mediated repression of Bax transcription. -- Abstract: CtBP is a transcriptional repressor which plays a significant role in the regulation of cell proliferation and tumor progression. It was reported that glucose withdrawal causes induction of Bax due to the dissociation of CtBP from the Bax promoter. However, the precise mechanism involved in the regulation of CtBP still remains unclear. In this study, we found that an activated AMP-activated protein kinase (AMPK) phosphorylates CtBP1 on Ser-158 upon metabolic stresses. Moreover, AMPK-mediated phosphorylation of CtBP1 (S158) attenuates the repressive function of CtBP1. We also confirmed that triggering activation of AMPK by various factors resulted in an increase of Bax gene expression. These findings provide connections of AMPK with CtBP1-mediated regulation of Bax expression for cell death under metabolic stresses.

  19. [An unusual case of fatal airbag injury].

    PubMed

    Usumoto, Yosuke; Hikiji, Wakako; Kudo, Keiko; Tsuji, Akiko; Ikeda, Noriaki

    2008-11-01

    We report an unusual case of fatal airbag injury. A woman in her forties was driving a light car when it was involved in an accident. When the car was found, the left front wheel had dropped into the gutter, the front bumper was dented and the airbag had deployed. Forensic autopsy revealed that the right subclavian artery and the left vertebral artery were ruptured and 1,570 ml and 360 ml of blood with clots were observed in the left and the right thoracic cavity, respectively. It was considered that the unusual collision produced by deployment of the airbag had caused these ruptures and massive hemorrhaging. Although an airbag is an effective tool for ensuring the safety of a driver and the passengers, it may injure and occasionally kill the occupants if they do not remain in the appropriate and restrained seating position. PMID:19198248

  20. Diagnostic accuracy of preoperative CT scanning of pituitary somatotroph adenomas.

    PubMed

    Marcovitz, S; Wee, R; Chan, J; Hardy, J

    1988-01-01

    Between 1980 and 1986, 58 patients (23 women and 35 men) had coronal CT scans of the sella turcica for suspected growth hormone-secreting adenoma and underwent transsphenoidal exploration. The CT examinations were performed with a fourth-generation EMI scanner (CT 7070), and reports of the preoperative CT were compared with the findings at transsphenoidal exploration. The same neurosurgeon performed all the operations. In three patients arthritic changes in the neck caused difficulties in positioning, which made it impossible to obtain adequate coronal CT scans. These nondiagnostic examinations are excluded from the statistical calculations. In all 55 patients with scans that were able to be evaluated, distinct adenomas were found at surgery. Among these were 39 macroadenomas (diameter larger than 10 mm) and 16 microadenomas. Three macroadenomas and two microadenomas caused combined hypersecretion of growth hormone and prolactin. All macroadenomas were localized correctly on the preoperative CT scans (sensitivity 100%), but in two cases there was a discrepancy in size of more than 5 mm compared with the operative findings. Preoperative CT scans correctly localized 13 of 16 microadenomas, for a sensitivity rate of 81.2%. Two patients with negative scans and one patient in whom the adenoma was found in a location other than that reported on the preoperative CT scan were considered to have negative scans for the purpose of statistical calculations. If both correct localization and size estimation within 2 mm of that found at surgery are considered, the accuracy rate was 90.9% for the entire group of patients, 94.9% for those with macroadenomas, and 81.2% for microadenomas. PMID:3124569

  1. Intracranial CT angiography obtained from a cerebral CT perfusion examination

    Microsoft Academic Search

    H. A. F. Gratama van Andel; H. W. Venema; C. B. Majoie; Heeten den G. J; C. A. Grimbergen; G. J. Streekstra

    2009-01-01

    CT perfusion (CTP) examinations of the brain are performed increasingly for the evaluation of cerebral blood flow in patients with stroke and vasospasm after subarachnoid hemorrhage. Of the same patient often also a CT angiography (CTA) examination is performed. This study investigates the possibility to obtain CTA images from the CTP examination, thereby possibly obviating the CTA examination. This would

  2. Extrarenal retroperitoneal angiomyolipoma with unusual evolution.

    PubMed

    Vîlcea, Ionic? Daniel; Victor, Radu; Mirea, Cecil Sorin; Simionescu, Cristiana Eugenia; Mogoant?, Stelian ?tef?ni??; Moraru, Emil; Vasile, Ioana Manuela; Ciorbagiu, Mihai C?lin; Obleag?, Cosmin Vasile; Crafciuc, Antoanela Valentina; Vasile, Ion; Vîlcea, Alina Maria; Gheonea, Cristian

    2015-01-01

    The aim of this paper is to present the case of an extrarenal retroperitoneal angiomyolipoma with unusual evolution, due to the herniation through the inguinal canal, determining an extraperitoneal hernia. A ureteral duplicity and associated hydronephrosis contributed to the peculiarity of the case. The case was operated (en block tumor and right kidney removal), the postoperative evolution being favorable at seven years after the surgery. PMID:25826514

  3. Total acquired vulval synechia: an unusual presentation.

    PubMed

    Kallam, Anji Reddy

    2015-04-01

    An unusual case of Acquired Total vulval synechia due to vulvar Lichen planus is reported in an 18-year-old girl, which is an extremely rare condition. It has a potential for producing extensive scarring and narrowing of introitus resulting in dyspareunia and rarely carcinoma of vulva. Successful surgical management of total vulvar synechiae in patient suffering from Lichen Planus is being reported. PMID:26023590

  4. Total Acquired Vulval Synechia: An Unusual Presentation

    PubMed Central

    2015-01-01

    An unusual case of Acquired Total vulval synechia due to vulvar Lichen planus is reported in an 18-year-old girl, which is an extremely rare condition. It has a potential for producing extensive scarring and narrowing of introitus resulting in dyspareunia and rarely carcinoma of vulva. Successful surgical management of total vulvar synechiae in patient suffering from Lichen Planus is being reported. PMID:26023590

  5. Sialolithiasis: an unusually large submandibular salivary stone.

    PubMed

    Siddiqui, S J

    2002-07-27

    Salivary gland calculi account for the most common disease of the salivary glands. The majority of sialoliths occur in the submandibular gland or its duct and are a common cause of acute and chronic infections. This case report describes a patient presenting with an unusually large submandibular gland sialolith, the subsequent patient management, the aetiology, diagnosis and various treatment modalities available for management of salivary gland calculi depending on their site and size. PMID:12199129

  6. Unusual radiologic manifestations of bronchogenic cyst.

    PubMed

    Dahmash, N S; Chen, J T; Ravin, C E; Reed, J C; Pratt, P C

    1984-06-01

    We have presented four cases of bronchogenic cyst, emphasizing the uncommon radiologic manifestations, including air trapping and/or lobulated contour. Two of the cysts were in the lung parenchyma, one in the left hilum adherent to the left lower lobe bronchus, and one in the posterior mediastinum. Recognition of the unusual radiologic features aids in establishing an appropriate differential diagnosis and directing subsequent evaluation. PMID:6729555

  7. Unusual Case of ALL with Ovarian Relapse.

    PubMed

    Sasidharan, P K; Sugeeth, M; Abdul Majeed, P; Shaan, Mohamed; Hitha, B

    2015-03-01

    Patients with acute lymphoblastic leukemia (ALL) can develop relapse in sanctuary sites like brain, ovary or testis even when the bone marrow is in remission. Pelvic recurrence is rarely reported during the follow up of successfully treated ALL in females. We report here a very unusual case of a large pelvic lump which the patient herself could feel, that was probably an ovarian relapse of ALL, successfully treated with re-induction chemotherapy alone and achieved complete remission. PMID:25548463

  8. An unusual combination: lipedema with myiasis.

    PubMed

    Koss, Tamara; Lanatra, Nicole; Stiller, Mathew J; Grossman, Marc E

    2004-06-01

    Lipedema refers to the abnormal deposition of subcutaneous fat causing a striking enlargement of the lower extremities that is out of proportion to the upper body. Most clinicians are unaware of this disease and thus it is seldom diagnosed correctly. Cutaneous myiasis is the infestation of skin by fly larvae. We describe an unusual case of a woman with lipedema who developed cutaneous myiasis. PMID:15153906

  9. An Unusual Manifestation of Q Fever: Peritonitis.

    PubMed

    Y?lmaz, Gülden; Öztürk, Bengi; Memiko?lu, Osman; Co?kun, Belgin; Yalç?, Aysun; Metin, Özge; Ünal, Hatice; Kurt, Halil

    2015-01-01

    Q fever has rarely been reported and can be difficult to diagnose, especially in immunocompromised patients. In the present report, we describe an unusual case of Q fever that presented as peritonitis and was treated with long-term combination therapy with doxycycline, ciprofloxacin and rifampicin for five weeks in a patient who had been on peritoneal dialysis for six years due to hypertensive nephropathy. PMID:25899561

  10. Segmental lichen planus pigmentosus: An unusual presentation

    PubMed Central

    Kumar, Y Hari Kishan; Babu, Anagha Ramesh

    2014-01-01

    Lichen planus pigmentosus (LPP) is a distinct clinical entity commonly encountered in the Indian population. It is considered a variant of lichen planus (LP). A 40-year-old male presented with asymptomatic hyperpigmented macules in a segmental distribution since 10 years that were clinically and histopathologically suggestive of LPP. We propose the terminology “segmental lichen planus pigmentosus” and report this unusual presentation. PMID:24860750

  11. Mechanism of an unusual decarboxylative cyclization

    Microsoft Academic Search

    Andrew S. Kende; Olivier Henry; Zecheng Chen

    2004-01-01

    The mechanism of an unusual decarboxylative cyclization from 5-methoxy-1-(2-carboxyphenyl)-1,4-dihydro-4-oxopyridine-2-carboxylic acid (diacid) to 3-methoxypyrido[1,2-a]indole-2,10-dione (ketone) has been investigated. 13C-labeling has demonstrated that the carbonyl carbon of the ketone arises exclusively from the anthranilic acid carboxyl of the diacid. A zwitterionic mechanism has been proposed.

  12. Unusual Bilateral Paramolars Associated with Clinical Complications

    PubMed Central

    Sulabha, A. N.; Sameer, C.

    2015-01-01

    Paramolars are rare supernumerary structures of maxillofacial complex that occur buccally or lingually near the molar row. Predominantly these occur singly; bilateral presentation is very rare. This paper reports two unusual bilateral presentations of paramolars with clinical complication and its management. One of the cases in the present paper also documents the cooccurrence of bilateral paramolars and microdontia of single tooth and one of its paramolars presented with multilobed crown with an anomalous buccal tubercle.

  13. Common Postmortem Computed Tomography Findings Following Atraumatic Death: Differentiation between Normal Postmortem Changes and Pathologic Lesions

    PubMed Central

    Gonoi, Wataru; Okuma, Hidemi; Shirota, Go; Shintani, Yukako; Abe, Hiroyuki; Takazawa, Yutaka; Fukayama, Masashi; Ohtomo, Kuni

    2015-01-01

    Computed tomography (CT) is widely used in postmortem investigations as an adjunct to the traditional autopsy in forensic medicine. To date, several studies have described postmortem CT findings as being caused by normal postmortem changes. However, on interpretation, postmortem CT findings that are seemingly due to normal postmortem changes initially, may not have been mere postmortem artifacts. In this pictorial essay, we describe the common postmortem CT findings in cases of atraumatic in-hospital death and describe the diagnostic pitfalls of normal postmortem changes that can mimic real pathologic lesions. PMID:26175579

  14. RamCT Training & Support RamCT Clear Java Files ACNS/Colorado State University

    E-print Network

    Rutledge, Steven

    RamCT Training & Support RamCT Clear Java Files ACNS/Colorado State University © May 2013 RamCT Training & Support RamCT Clear Java Files ACNS/Colorado State University © May 2013 If You Selected DonCT Training & Support RamCT Clear Java Files ACNS/Colorado State University © May 2013 Delete Temporary Files

  15. The Unusual Chance Fracture: Case Report & Literature Review

    PubMed Central

    Karargyris, O; Morassi, LG; Zafeiris, C; Evangelopoulos, DS; Pneumaticos, SG

    2013-01-01

    The Chance fracture represents a spinal lesion caused by a flexion-distraction injury pattern. We describe a rare case of a male driver admitted at the Emergencies of our Institution, level A Trauma center. The was involved in an automobile accident without wearing a seatbelt. Radiological findings of plain radiography and computed tomography (CT) demonstrated a horizontal fracture extending across the vertebral body to the posterior elements with loss of vertebral height at the anterior aspect of T12. Based on these findings, the diagnosis of a T12 Chance fracture was established. The patient was treated conservatively with a thoracolumbar orthosis, without any subsequent disabilities. Although Chance fractures are rare lesions, they should always be considered in spinal injuries, even in cases of motor-vehicle accidents where no seatbelt is used. PMID:24015161

  16. Diagnostic Performance of CT Colonography for the Detection of Colorectal Polyps

    PubMed Central

    Ro, Hee Jeong; Park, Jong Beom; Choi, Jung-Bin; Chung, Ji Eun; Kim, Yong Jin; Suh, Won Hyuck; Lee, Jong Kyun

    2007-01-01

    Objective To investigate the diagnostic value of CT colonography for the detection of colorectal polyps. Materials and Methods From December 2004 to December 2005, 399 patients underwent CT colonography and follow-up conventional colonoscopy. We excluded cases of advanced colorectal cancer. We retrospectively analyzed the CT colonography findings and follow-up conventional colonoscopy findings of 113 patients who had polyps more than 6 mm in diameter. Radiologists using 3D and 2D computer generated displays interpreted the CT colonography images. The colonoscopists were aware of the CT colonography findings before the procedure. Results CT colonography detected 132 polyps in 107 of the 113 patients and conventional colonoscopy detected 114 colorectal polyps more than 6 mm in diameter in 87 of the 113 patients. The sensitivity of CT colonography analyzed per polyp was 91% (41/45) for polyps more than 10 mm in diameter and 89% (101/114) for polyps more than 6 mm in diameter. Thirteen polyps were missed by CT colonography and were detected on follow-up conventional colonoscopy. Conclusion CT colonography is a sensitive diagnostic tool for the detection of colorectal polyps and adequate bowel preparation, optimal bowel distention and clinical experience are needed to reduce the rate of missing appropriate lesions. PMID:18071278

  17. Renal malignant solitary fibrous tumor with single lymph node involvement: report of unusual metastasis and review of the literature

    PubMed Central

    Mearini, Ettore; Cochetti, Giovanni; Barillaro, Francesco; Fatigoni, Sonia; Roila, Fausto

    2014-01-01

    Solitary fibrous tumors are rare mesenchymal spindle cell neoplasms that are usually found in the pleura. The kidneys are an uncommon site and only few cases of renal solitary fibrous tumor exhibit malignant behavior metastasizing to the liver, lung, and bone through the hematogenous pathway. Purpose To describe the first case of lymph node metastasis from renal solitary fibrous tumor in order to increase the knowledge about the malignant behavior of these tumors. Patients and methods A 19-year-old female patient had intermittent hematuria for several months without flank pain or other symptoms. A chest and abdomen CT scan was performed and showed a multi-lobed bulky solid mass of 170 × 98 × 120 mm in the left kidney. One day before the surgery, the left renal artery was catheterized and the kidney embolization was performed using a Haemostatic Absorbable Gelatin Sponge and polyvinyl alcohol. We then performed a radical nephrectomy with hilar, para-aortic, and inter-aortocaval lymphadenectomy. Results Estimated intraoperative blood loss was 200 mL and the operative time was 100 minutes. No postoperative complications occurred. The hospital stay was 7 days long. The histological examination was malignant solitary fibrous tumor of the kidney. Cancerous tissue showed cellular atypia, with an increased mitotic index (up to 7 × 10 hpf). Immunohistochemical analysis showed positive results for CD34, BCL2, partial expression of HBME1, and occasionally of synaptophysin. Histological evaluation confirmed the presence of metastasis in one hilar node. The patient did not receive any other therapy. At 30-month follow-up, the patient was in good health and no local recurrence or metastases had occurred. Conclusion This is the first case of lymph node metastasis from a renal solitary fibrous tumor showing unusual malignant behavior; this finding adds new information about the biology and progression of these tumors, which remain unclear. PMID:24855378

  18. CT Reconstruction and Functional Imaging

    E-print Network

    Bartz, Dirk

    (Spiral) CT Tutorial 3IEEE Visualization 2005 Data Acquisition: Cone-Beam #12;2 Tutorial 3IEEE expensive than MRI) Tutorial 3IEEE Visualization 2005 Comparison: Cone-Beam CT One rotation covers a large resolution (6-8 mm) · tracer decay slower - therefore longer-lasting effects can be monitored - tracers don

  19. CT navigated lateral interbody fusion.

    PubMed

    Drazin, Doniel; Liu, John C; Acosta, Frank L

    2013-10-01

    Lateral interbody fusion techniques are heavily reliant on fluoroscopy for retractor docking and graft placement, which expose both the patient and surgeon to high doses of radiation. Use of image-guided technologies with CT-based images, however, can eliminate this radiation exposure for the surgeon. We describe the surgical technique of performing lateral lumbar interbody fusion using CT navigation. PMID:23931938

  20. CT of Hepatic Tumors: Prevalence and Specificity of Retraction of the Adjacent Liver Capsule

    Microsoft Academic Search

    Philippe Soyer; David A. Bluemke; Christiane Vissuzaine; Marc Levesque

    OBJECTIVE. The purpose of this study was to describe the CT features of capsular retraction of the liver adjacent to hepatic tumors and to test the hypothesis that this finding is specific for malignant hepatic tumors. MATERIALS AND METHODS. We first retrospectively reviewed the CT scans of eight patients with pathologically proved malignant hepatic tumors (five secondary and three primary)

  1. CT in the evaluation of patients on ECMO due to acute respiratory failure

    Microsoft Academic Search

    Marika Lidegran; Kenneth Palmér; Håkan Jorulf; Viveka Lindén

    2002-01-01

    Background. In patients with acute severe respiratory failure (ARF) treated with extracorporeal membrane oxygenation (ECMO) the radiological evaluation has until now almost exclusively relied on bedside radiography and US. At St. Göran\\/Karolinska ECMO centre CT has become a routine complement to bedside examinations. Objective. To review retrospectively the frequency, indications and findings on CT of patients with ARF on ECMO

  2. ORIGINAL RESEARCH MTHFR 677C>T effects on anterior cingulate structure

    E-print Network

    Manoach, Dara S.

    ORIGINAL RESEARCH MTHFR 677C>T effects on anterior cingulate structure and function during response heritable alterations of dACC function. We examined whether the hypofunctional 677C>T variant in MTHFR fractional anisotropy in bilateral dACC. These findings suggest that the MTHFR 677T allele blunts response

  3. Diagnosis of Bowel Infarction: A Comparison of Plain Films and CT Scans in 23 Cases

    Microsoft Academic Search

    Michael J. Smerud; C. Daniel Johnson; David H. Stephens

    We retrospectively reviewed abdominal CT and plain film findings in 23 proved cases of mesenteric infarction to compare the value of the two techniques. Criteria considered specific for infarction on CT were identified in nine (39%) of 23 patients and comprised pneumatosis in seven patients (30%), mesenteric or portal venous gas in three patients (13%), and focally thick-walled bowel in

  4. Adding Liver Window Setting to the Standard Abdominal CT Scan Protocol: Is It Useful?

    Microsoft Academic Search

    S. Sabouri; A. Khatami; P. Azadeh; J. Ghoroubi

    2008-01-01

    Background\\/Objective: Hepatic lesions may be missed in the routine abdominal computed tomography (CT) scan protocol using soft tissue window setting. The ability to find these lesions is very important in the assessment of metastasis and follow-up of patients. Patients and Methods: In this study, 411 patients who underwent abdominal CT for various causes were evaluated separately by two radiologists blindly.

  5. Metastatic Pulmonary Calcification in Patients with Hypercalcemia: Findingson Chest Radiographsand CT Scans

    Microsoft Academic Search

    Nestor L. Muller; Steven L. Primack; Takeshi Johkoh; Noriyuki Takeuchi; Stephen J. Swensen

    OBJECTIVE. The objective of this study was to characterize the findings on chest radiographs and CT scans in patients with metastatic pulmonary calcification due to hypercalcemla. MATERIALS AND METHODS. The chest radiographs and CT scans of seven patients with biopsy-proved metastatic pulmonary calcification were reviewed by two observers. Metastatic calcification was due to chronic renal failure (n = 4), T-cell

  6. Histoplasmosis of the adrenal glands studied by CT

    SciTech Connect

    Wilson, D.A.; Muchmore, H.G.; Tisdal, R.G.; Fahmy, A.; Pitha, J.V.

    1984-03-01

    Computed tomography (CT) of the adrenal glands was performed on seven patients who had histologically proved disseminated histoplasmosis. All seven patients showed some degree of adrenal gland abnormality. The range of CT findings included minimal enlargement with faint flecks of calcium, moderate enlargement with focal low attenuation nodules, and massive enlargement with large areas of necrosis or dense calcification. The changes in each patient were bilateral and symmetrical. Adrenal gland shape was usually preserved. Finding of percutaneous adrenal biopsy, which was performed under CT guidance, made the diagnosis in one patient. Five of seven patients had adrenal insufficiency. It is concluded that the diagnosis of disseminated histoplasmosis should be considered in any patient who has bilateral adrenal gland enlargement and who resides in an endemic area, especially if there is evidence of adrenal insufficiency.

  7. CT of the chest in the evaluation of idiopathic pulmonary arterial hypertension in children

    Microsoft Academic Search

    Gulraiz Chaudry; Cathy MacDonald; Ian Adatia; Munire Gundogan; David Manson

    2007-01-01

    Background  Idiopathic pulmonary arterial hypertension (IPAH) is a rare disease in children. By definition it is a diagnosis of exclusion,\\u000a and CT of the chest is primarily performed to exclude other causes. Previous studies have defined CT features suggestive of\\u000a the diagnosis of IPAH, but these have all been limited to the adult population.\\u000a \\u000a \\u000a \\u000a Objective  Contrast-enhanced chest CT and high-resolution CT findings

  8. Lingual mandibular bony defects: CT in the buccolingual plane

    SciTech Connect

    Slasky, B.S.; Bar-Ziv, J. [Hebrew Univ., Jerusalem (Israel)] [Hebrew Univ., Jerusalem (Israel)

    1996-05-01

    Our goal was to record the appearance of lingular mandibular bony defects (LMBD) on CT imaging of the mandible in the buccolingual plane. During the CT evaluation of patients planning to undergo dental implant surgery, five cases of LMBD were found. Axial 1.2 x 1.00 mm overlapping CT sections of the mandible and the maxilla were obtained. Then with use of specific software (DentaCT; Elscint), panoramic and cross-sectional (buccolingual) images of the mandible and maxilla were reformatted. Five cases of posterior LMBD were identified; one patient had both a posterior as well as the much rarer anterior LMBD. All cases were incidental findings and all were asymptomatic. CT features of LMBD were displayed it axial, panoramic, and buccolingual planes. The characteristic opening of the bony defect in the lingual aspect of the mandible was clearly displayed on the axial as well as the buccolingual images; however, this key feature was not manifest on the panoramic images; however, this key feature was not manifest on the panoramic images of the mandible. CT features of LMBD in the buccolingual plane are added to the known radiologic description of this entity. 8 refs., 6 figs.

  9. Imaging of extranodal lymphoma with PET/CT.

    PubMed

    Ilica, Ahmet Turan; Kocacelebi, Kenan; Savas, Recep; Ayan, Asli

    2011-10-01

    Hodgkin disease (HD) and non-Hodgkin lymphoma (NHL) represent a spectrum of malignant neoplasms arising from the lymphoid system with an incidence of around 8% of all malignancies. Although they are generally known as tumors of lymph nodes, 25% to 40% of HD/NHL tumors, especially NHL, arise at extranodal sites along the gastrointestinal tract, head and neck, orbit, central and peripheral nervous system, thorax, bone, skin, breast, testis, thyroid, and genitourinary tract. Extranodal involvement is an important pretreatment prognostic factor for patients with lymphoma and its incidence has increased in the past 2 decades. Imaging plays an important role in the noninvasive pretreatment assessment of patients with extranodal lymphoma. This involvement can be subtle and may be overlooked during computed tomography (CT). Positron emission tomography/CT (PET/CT) has evolved into an important imaging tool for evaluation of lymphomas, facilitating the detection of affected extranodal sites even when CT shows subtle or no obvious lesions. Familiarity with extranodal manifestations and suggestive PET/CT features in different sites is important for accurate evaluation of lymphoma. This article reviews the extranodal PET/CT imaging findings regarding HD and NHL. PMID:21892025

  10. Radiological findings in acute Haemophilus influenzae pulmonary infection

    PubMed Central

    Okada, F; Ando, Y; Tanoue, S; Ishii, R; Matsushita, S; Ono, A; Maeda, T; Mori, H

    2012-01-01

    Objective The aim of this study was to assess pulmonary thin-section CT findings in patients with acute Haemophilus influenzae pulmonary infection. Methods Thin-section CT scans obtained between January 2004 and March 2009 from 434 patients with acute H. influenzae pulmonary infection were retrospectively evaluated. Patients with concurrent infection diseases, including Streptococcus pneumoniae (n=76), Staphylococcus aureus (n=58) or multiple pathogens (n=89) were excluded from this study. Thus, our study group comprised 211 patients (106 men, 105 women; age range, 16–91 years, mean, 63.9 years). Underlying diseases included cardiac disease (n=35), pulmonary emphysema (n=23), post-operative status for malignancy (n=20) and bronchial asthma (n=15). Frequencies of CT patterns and disease distribution of parenchymal abnormalities, lymph node enlargement and pleural effusion were assessed by thin-section CT. Results The CT findings in patients with H. influenzae pulmonary infection consisted mainly of ground-glass opacity (n=185), bronchial wall thickening (n=181), centrilobular nodules (n=137) and consolidation (n=112). These abnormalities were predominantly seen in the peripheral lung parenchyma (n=108). Pleural effusion was found in 22 patients. Two patients had mediastinal lymph node enlargement. Conclusion These findings in elderly patients with smoking habits or cardiac disease may be characteristic CT findings of H. influenzae pulmonary infection. PMID:21224303

  11. Marine dolomite of unusual isotopic composition.

    PubMed

    Russell, K L; Deffeyes, K S; Fowler, G A; Lloyd, R M

    1967-01-13

    A piston core taken off of the coast of Oregon in 358 meters of water contained an indurated calcareous layer composed partly of dolomite with a composition Ca(58.7)Mg(41.3). Dolomites of this chemical composition are typical of the supratidal environment. However, the dolomite has isotopic composition delta0(18) = 5.8 per mille, deltaC(13) = 35.1 per mille relative to the Chicago PDB-I standard. The unusual carbon isotope ratio is similar to that of calcites produced as a byproduct of bacterial breakdown of hydrocarbons. PMID:17738221

  12. An unusual case of shoulder pain.

    PubMed

    Slipman, C W; Shin, C H; Ellen, M I; Patel, R K; Braverman, D; Lenrow, D

    2000-10-01

    Shoulder pain is a common musculoskeletal ailment. The process of determining the etiology of shoulder pain can be difficult. The differential diagnoses include: both intracapsular and extracapsular lesions; and neurologic, vascular, postural, and visceral causes. We present an unusual case of shoulder pain accompanied by loss of shoulder range of motion (ROM), initially thought to be caused by an intrinsic shoulder disorder. However, it ultimately was determined that a cervical radicular disorder caused both the impaired ROM and the patient's shoulder pain. PMID:16906176

  13. Diabetic ketoacidosis: an unusual presentation of acromegaly

    PubMed Central

    Dosi, Rupal V; Patell, Rushad D; Shah, Pratik J; Joshi, Harshal K

    2013-01-01

    Secondary diabetes mellitus is known to occur in acromegaly due to insulin resistance caused by growth hormone excess. However, diabetes in acromegaly usually does not lead to ketosis. We describe an unusual case of a patient that presented with diabetic ketoacidosis in the emergency room with thirst, polyuria and dyspnoea. The patient was subsequently diagnosed with a growth hormone-secreting pitutary macroadenoma as the underlying pathology; after initial stabilisation with insulin and fluids, the patient was successfully treated with trans-sphenoidal surgery. PMID:23761570

  14. Unusual bond paths in organolithium compounds

    SciTech Connect

    Bachrach, S.M.; Ritchie, J.P.

    1986-01-01

    We have applied the topological method to a number of organolithium compounds. The wavefunctions were determined with GAUSSIAN-82 using 3-21G basis set and fully optimized geometries. Gradient paths were obtained using the RHODER package and critical points were located using EXTREME. These results indicate the unusual nature of organolithium compounds. The strange bond paths arise mainly from the ionic nature of the C-Li interaction. We suggest that the term ''bond path'' may best be suited for covalent bonds. 4 figs., 1 tab.

  15. Fatal bupivacaine intoxication following unusual erotic practices.

    PubMed

    Yazzie, Janice; Kelly, Sean C; Zumwalt, Ross E; Kerrigan, Sarah

    2004-03-01

    A fatal drug overdose is described which involved unusual erotic practices. A 54-year-old male was discovered supine on the floor surrounded by sexual paraphernalia, syringes, and medications including three empty bottles of bupivacaine. Acute and chronic injection sites of the external genitalia with contusions, scarring, focal necrosis, and calcification were present at autopsy. Toxicology revealed femoral blood, heart blood, and vitreous bupivacaine concentrations of 3.8, 2.8 and 1.3 mg/L, respectively. The urine bupivacaine concentration was 11.4 mg/L. The cause of death was attributed to bupivacaine intoxication and the manner of death was accidental. PMID:15027559

  16. [Muscular disorders: unusual or focal presentations].

    PubMed

    Campana-Salort, Emmanuelle

    2008-12-31

    Despite major development of complementary investigations, diagnosis of muscular disorders is mainly clinical. Myopathies can present with unusual or atypical clinical features: myotonia, periodic paralysis, respiratory failure, swallowing difficulties, ptosis, ophtalmoplegia, camptocormia, distal or asymmetrical limb muscle weakness. It can be cause of inaccurate diagnosis. The clinical variability of muscular disorders must be recognized by physicians to drive diagnosis process and to offer an opportunity for early interventional management strategies. This paper reviews the main atypical clinical features of myopathies and their causes. PMID:19209655

  17. Forced flow evaporator for unusual gravity conditions

    NASA Technical Reports Server (NTRS)

    Niggemann, Richard E. (Inventor); Ellis, Wilbert E. (Inventor)

    1987-01-01

    Low efficiency heat transfer in evaporators subject to unusual gravitational conditions is avoided through the use of a spiral evaporator conduit 12 receiving at an inlet 14 a vaporizable coolant at least partly in the liquid phase. Flow of the coolant through the conduit 12 demists the coolant by centrifuging the liquid phase against a pressurre wall 44 of the conduit 12. Vapor flow 40 induces counterrotating vortices 46, 48 which circulate the liquid phase coolant around the interior of the conduit 12 to wet all surfaces thereof.

  18. Put your back into it: pathologic conditions of the spine at chest CT.

    PubMed

    Meyer, Cristopher A; Vagal, Achala S; Seaman, Danielle

    2011-01-01

    It is common to encounter pathologic processes of the lower cervical, thoracic, or upper lumbar spine in the course of routine computed tomography (CT) of the chest. Although magnetic resonance (MR) is the imaging modality of choice for evaluating known spinal disease, evaluation of the spine is an integral part of interpreting a chest CT study. Spinal diseases often have a characteristic CT appearance that allows the radiologist to make the diagnosis or provide a structured differential diagnosis. Pathologic conditions of the spine that can be identified at chest CT are categorized into benign or incidental findings, congenital anomalies, traumatic injuries, infectious spondylitis, primary or secondary neoplastic involvement, and associations with systemic disease. CT also provides information about bone mineralization and lesion calcification that complements the superior soft-tissue imaging capability of MR. In addition, chest CT data may be reformatted to create volumetric or multiplanar images of the spine to facilitate management decisions about spinal stabilization in symptomatic patients. PMID:21918053

  19. Characterization of scatter radiation in cone beam CT mammography

    Microsoft Academic Search

    Bob Liu; Stephen J. Glick; Corinne Groiselle

    2005-01-01

    Cone beam CT mammography (CBCTM) is an emerging breast imaging technology and is currently under intensive investigation [1-3]. One of the major challenges in CBCTM is to understand the characteristics of scatter radiation and to find ways to reduce or correct its degrading effects. Since the breast shape, geometry and image formation process are significantly different from conventional mammography, all

  20. Leigh's subacute necrotizing encephalomyelopathy: Possible diagnosis by CT scan

    Microsoft Academic Search

    Je G. Chi; Han Wook Yoo; Ki Hyun Chang; Chul Woo Kim; Hyung Ro Moon; Kwang Wook Ko

    1981-01-01

    A 28-month-old Korean girl developed a rapidly progressive disease, characterized by disturbance of consciousness, tremor, nystagmus, ophthalmoplegia, irregular deep respiration and vomiting. The patient succumbed 2 weeks after the onset of the illness. CT scan disclosed bilaterally symmetrical, low density lesions in the white matter and lateral basal ganglia. Distinctive histopathological findings at postmortem included spongiotic necrosis of the neuropil,

  1. Using GVF Snake to Segment Liver from CT Images

    Microsoft Academic Search

    Shaohui Huang; Boliang Wang; Xiaoyang Huang

    2006-01-01

    Liver segmentation on computed tomography (CT) images is a challenging task because the images are often corrupted by noise and sampling artifacts. Thus we choose GVF snake to perform the task. Unfortunately, GVF snake use Gaussian function to generate the edge map. We find that this often cause new problems such as blur the liver boundary. To avoid this, a

  2. Group A Escherichia coli-Related Purpura Fulminans: an Unusual Manifestation Due to an Unusual Strain?

    PubMed Central

    Amara, Marlène; Bonacorsi, Stéphane; Bedel, Jérôme; Mira, Jean-Paul; Laurent, Virginie; Socha, Koryna; Bruneel, Fabrice; Pangon, Béatrice; Bédos, Jean-Pierre

    2014-01-01

    We describe an exceptional case of life-threatening group A Escherichia coli-induced purpura fulminans. Genotyping of common polymorphisms in genes involved in innate immunity or coagulation did not reveal known susceptibility to such a manifestation. Genetic analysis of the strain revealed an unusual conserved virulence plasmidic region, pointing out its potential virulence. PMID:25232165

  3. Evaluation of Early Computed Tomographic Findings in Acute Ischemic Stroke

    Microsoft Academic Search

    Michael P. Marks; Eric B. Holmgren; Allan J. Fox; Suresh Patel; Rudiger von Kummer; Juergen Froehlich

    Background and Purpose—Detection of large, hypoattenuated brain-tissue volume on hyperacute CT scan has been suggested as an exclusion criterion for early intravenous tissue plasminogen activator (IV-tPA) treatment. This study assessed the reliability of detection for these findings and their relationship to outcome. Methods—Fifty hyperacute CT scans ( ,6 hours after ictus) were selected from a randomized trial evaluating IV-tPA (ATLANTIS

  4. Unusual case of acute tracheal injury complicated by application of positive end expiratory pressure (PEEP).

    PubMed

    Farooqui, Asif Masroor; Mbarushimana, Simon; Faheem, Mohammad

    2014-01-01

    Blunt neck trauma can be caused by a variety of injuries such as deceleration, road traffic accidents and crush injuries. The worst scenario is airway rupture. We report an unusual case of acute tracheal injury in a 34-year-old Irish man who presented with a history of strangulation while working with a tractor. On arrival, he had one episode of mild haemoptysis and reported pain around the base of the neck and voice hoarseness. His chest X-ray revealed pneumopericardium and CT of thorax showed airway oedema. After elective intubation, positive end-expiratory pressure (PEEP) of 5 cm H2O caused deterioration in his clinical condition with increasing surgical emphysema and rise of carbon dioxide partial pressure (PaCO2), which was completely reversed after stopping PEEP. This case shows how PEEP and intermittent positive pressure ventilation can worsen air leak and compromise stability in patients with acute tracheal injury. PMID:25398917

  5. An unusual case of lead snowstorm caused by fragmentation of buckshot.

    PubMed

    Pavelites, Joseph J; Prahlow, Joseph A; Landrum, Jeffry E; Zollinger, David; Vermillion, Daniel

    2011-09-01

    This article reports the unusual radiographic findings of 2 cases of a shotgun shooting incident involving the homicide of a plant manager and the subsequent suicide of the assailant. Radiologic examination of wounds produced by the no. 00 copper-plated buckshot used in the incident revealed images with striking similarity to the lead snowstorm appearance generally associated with high-velocity, soft-point rifle bullets. PMID:21817870

  6. Photometric study of the unusual binary system vsx j052807.9 + 725606

    Microsoft Academic Search

    N. A. Virnina; I. L. Andronov; K. A. Antonyuk

    2011-01-01

    Results are reported from a three color (B, V, and R) photometric study of the recently discovered, unusual binary system VSX J052807.9 + 725606 = USNO-B1.0 1629-0064825. This system is extremely similar to the system V361 Lyr, which had previously been regarded as unique. We confirm the strong asymmetry of the phase curve and find that its amplitude depends on

  7. CT Demonstration of Caput Medusae

    ERIC Educational Resources Information Center

    Weber, Edward C.; Vilensky, Joel A.

    2009-01-01

    Maximum intensity and volume rendered CT displays of caput medusae are provided to demonstrate both the anatomy and physiology of this portosystemic shunt associated with portal hypertension. (Contains 2 figures.)

  8. Hepatic hemangioma: dynamic bolus CT.

    PubMed

    Freeny, P C; Marks, W M

    1986-10-01

    Forty-seven patients with 58 hepatic hemangiomas were studied prospectively with a dynamic bolus CT protocol (single-level or incremental scans) that included precontrast scans, rapid-sequence scanning during the IV bolus injection of 150 ml of 60% contrast agent, and delayed scans taken as long as 60 min after contrast. Three CT criteria are believed to be necessary to make a specific diagnosis of hemangioma: lesion with diminished attenuation on precontrast scan; peripheral contrast enhancement during the dynamic bolus phase of scanning; and complete isodense fill-in on delayed scans obtained up to 60 min after contrast. These CT criteria were seen in only 32 (55%) of 58 hemangiomas, making CT a relatively poor imaging technique for diagnosis. PMID:3489370

  9. Synthetic Hounsfield units from spectral CT data

    NASA Astrophysics Data System (ADS)

    Bornefalk, Hans

    2012-04-01

    Beam-hardening-free synthetic images with absolute CT numbers that radiologists are used to can be constructed from spectral CT data by forming ‘dichromatic’ images after basis decomposition. The CT numbers are accurate for all tissues and the method does not require additional reconstruction. This method prevents radiologists from having to relearn new rules-of-thumb regarding absolute CT numbers for various organs and conditions as conventional CT is replaced by spectral CT. Displaying the synthetic Hounsfield unit images side-by-side with images reconstructed for optimal detectability for a certain task can ease the transition from conventional to spectral CT.

  10. HOT SAX: Efficiently Finding the Most Unusual Time Series Subsequence Eamonn Keogh Jessica Lin

    E-print Network

    Fu, Ada Waichee

    with objective experiments on domains as diverse as Space Shuttle telemetry monitoring, medicine, surveillance anomalies in domains as diverse as Space Shuttle telemetry, industry, and medicine. One reason why discords such a definition here and validate it in domains as diverse as medicine, surveillance, and space telemetry. Second

  11. Endobronchial tumor in children: Unusual finding in recurrent pneumonia, report of three cases.

    PubMed

    Madafferi, Silvia; Catania, Vincenzo D; Accinni, Antonella; Boldrini, Renata; Inserra, Alessandro

    2015-05-01

    We are reporting 3 cases of pediatric endobronchial tumors presented with recurrent pneumonia. The median age of patients, at time of presentation, was 10.6 years. All patients presented with recurrent pneumonia with a mean time to occurrence, after onset of symptoms, of 14 mo. Bronchoscopy was early performed as part of diagnostic work-up and it revealed an endobronchial mass in every case. Complete surgical resection was performed in all cases, with lung preservation in two of them. Neither post-operative chemotherapy nor radiotherapy was required. The mean duration of follow-up was 7 years and all patients are still alive and disease-free. Recurrent pneumonia, in pediatrics, should raise the suspicion of an obstructing lesion, congenital malformation or systemic disease. A systematic approach is useful for organize the clinicians initial workup. Prompt diagnosis allows parenchymal-sparing surgery, which offers the best chance of cure and reduces clinical and functional complications in these patients. PMID:26015878

  12. CT of Hepatic Sarcoidosis: Small Nodular Lesions Simulating Metastatic Disease

    PubMed Central

    Ufuk, Furkan; Herek, Duygu

    2015-01-01

    Summary Background Sarcoidosis is a multisystemic inflammatory disease of unknown origin. The lymphoid system and the lungs are the most commonly involved organs. The frequency of signs or symptoms of hepatic involvement is very low. Case Report We present a case of symptomatic granulomatous liver disease secondary to sarcoidosis, mimicking a metastatic disease on ultrasonography and CT. Conclusions Hepatic involvement in sarcoidosis might be a perplexing diagnostic problem. The decisive CT finding with respect to the differential diagnosis was the absence of a mass effect and intact vascular architecture around the lesions. PMID:25908950

  13. Pyogenic liver abscess: an unusual cause.

    PubMed

    Dinnoo, A; Barbier, L; Soubrane, O

    2015-02-01

    A 60-year-old female patient was referred for a massive pyogenic liver abscess that had been initially treated with percutaneous drainage and antibiotics. CT-scan showed a foreign body in the hepatic pedicle, adjacent to the right portal vein: a fishbone. After 6 weeks of medical management with antibiotics, the foreign body was removed laparoscopically. The presence of a foreign body should be sought in cases of pyogenic liver abscess, especially if no other intra-abdominal cause has been found or if the abscess fails to resolve with medical treatment alone. PMID:25662871

  14. Imaging findings in neurocysticercosis.

    PubMed

    García, Héctor H; Del Brutto, Oscar H

    2003-06-01

    The diagnosis of neurocysticercosis was greatly improved by the introduction of computed tomography (CT) and magnetic resonance imaging (MRI). These techniques demonstrate the number and topography of lesions, their stage of involution, and the degree of inflammatory reaction of the host against the parasites and have largely replaced previous radiological procedures such as plain roentgenograms, pneumoencephalograms, cerebral angiography and myelography. In general, MRI provides better image detection and definition. The possibility of multiplanar reconstruction of images, its capability to visualize the posterior fossa without bone artifacts, and its high contrast resolution (far superior to that of CT) allow MRI to recognize many forms of cysticercosis not visualized on CT. However, the costs of MRI are high and the equipment is scarcely available in many endemic countries, and its sensitivity for the detection of calcified lesions is poor. CT remains the best screening neuroimaging procedure for patients with suspected neurocysticercosis, and MRI is the imaging modality of choice for the evaluation of patients with intraventricular cysticercosis, brainstem cysts and small cysts located over the convexity of cerebral hemispheres. Its better image definition also suggests that MRI is superior to CT in the follow-up of the patients after therapy. PMID:12781380

  15. Chandra X-Ray Observations of Two Unusual BAL Quasars

    E-print Network

    Rogerson, Jesse A; Snedden, Stephanie A; Brotherton, Michael S; Anderson, Scott F

    2010-01-01

    We report sensitive Chandra X-ray non-detections of two unusual, luminous Iron Low-Ionization Broad Absorption Line Quasars (FeLoBALs). The observations do detect a non-BAL, wide-binary companion quasar to one of the FeLoBAL quasars. We combine X-ray-derived column density lower limits (assuming solar metallicity) with column densities measured from ultraviolet spectra and CLOUDY photoionization simulations to explore whether constant-density slabs at broad-line region densities can match the physi- cal parameters of these two BAL outflows, and find that they cannot. In the "overlapping-trough" object SDSS J0300+0048, we measure the column density of the X-ray absorbing gas to be NH >= 1.8 x 1024 cm-2. From the presence of Fe ii UV78 absorption but lack of Fe ii UV195/UV196 absorption, we infer the density in that part of the absorbing region to be ne ~ 106 cm-3. We do find that a slab of gas at that density might be able to explain this object's absorption. In the Fe iii-dominant object SDSS J2215-0045, the ...

  16. Hexaaminobenzene derivatives: synthesis and unusual oxidation behavior.

    PubMed

    Wolff, J J; Zietsch, A; Nuber, B; Gredel, F; Speiser, B; Würde, M

    2001-04-20

    The syntheses and the electrochemical behavior of the monomeric peralkylated hexaamino(1,3)metacyclophane 4, the dimeric dodecaamino(1,3)cyclophane 5a, and the dodecaamino(1,3,5)cyclophane 6 are described. Electrochemical measurements show that the hexaaminobenzene units in 4 and 5a undergo an unusually slow two-electron transfer attributed to the deformation of the rings into bis-cyanine cations when oxidized to the respective dication. Further oxidations to tri-, tetra-, and hexacationic units occur at more positive potentials. In the dimeric structures, no interaction between the rings can be seen in the (1,3)cyclophane, but strong interaction for the (1,3,5)cyclophane is observed. PMID:11304200

  17. Unusual presentation in Axenfeld-Rieger syndrome

    PubMed Central

    Parikh, Rajul S; Parikh, Shefali R; Debashish, B; Harsha, B L; Thomas, Ravi

    2011-01-01

    We report an unusual presentation of a case of Axenfeld-Rieger (A-R) syndrome. A 14-year-old male presented with gradual dimness of vision for 1 year and redness of left eye for 3 days. The patient had megalocornea with Haab's striae in the right eye and posterior embryotoxon in both the eyes. In the left eye, there was a white cord-like structure traversing the anterior chamber with adhesions to iris tissue along its course. On two antiglaucoma medications, his intraocular pressure (IOP) was 22 mm Hg in the right eye and 18 mm Hg in the left eye. Gonioscopy revealed a cord-like structure originating at the level of Schwalbe's line. He underwent right eye trabeculectomy with mitomycin-C. This case highlights a rare presentation of a strange cord-like structure, a rare presentation of A-R syndrome. PMID:21666320

  18. Unusual Cytochrome P450 Enzymes and Reactions*

    PubMed Central

    Guengerich, F. Peter; Munro, Andrew W.

    2013-01-01

    Cytochrome P450 enzymes primarily catalyze mixed-function oxidation reactions, plus some reductions and rearrangements of oxygenated species, e.g. prostaglandins. Most of these reactions can be rationalized in a paradigm involving Compound I, a high-valent iron-oxygen complex (FeO3+), to explain seemingly unusual reactions, including ring couplings, ring expansion and contraction, and fusion of substrates. Most P450s interact with flavoenzymes or iron-sulfur proteins to receive electrons from NAD(P)H. In some cases, P450s are fused to protein partners. Other P450s catalyze non-redox isomerization reactions. A number of permutations on the P450 theme reveal the diversity of cytochrome P450 form and function. PMID:23632016

  19. Unusual patterns of I-131 contamination.

    PubMed

    Ozguven, Mehmet; Ilgan, Seyfettin; Arslan, Nuri; Karacalioglu, A Ozgur; Yuksel, Dogangun; Dundar, Sabri

    2004-05-01

    Whole body imaging with radioiodine can detect functioning metastases, which can often be effectively treated with appropriate amounts of radioiodine. Non-physiologic I-131 uptake detected on images is usually interpreted as suggesting functioning thyroid metastases. However, extra-thyroidal I-131 accumulation does not always imply thyroid cancer metastases and has been reported on many occasions, including various non-thyroidal neoplasms, and contamination by body secretions. In order to avoid unnecessary therapeutic interventions it is extremely important to properly distinguish false-positive sites of I-131 localization. Three patients with unusual radioiodine contamination patterns, either presented for the first time or rarely presented in the existing literature, were reported. Reported cases consist of contamination in hair (due to styling hair with sputum), contamination in neck (due to drooling during sleep) and, contaminated chewing gum. False positive contamination sources were clarified by careful examination of patients and further images when necessary. PMID:15233290

  20. Unusual isolated tubercolous epididymitis. Case report

    PubMed Central

    DELL’ATTI, L.

    2014-01-01

    We present an unusual case of tuberculous epididymitis in a 33-year-old African patient, who was referred to our Department of Urology with a right intrascrotal mass. There was no evidence of fever, hematuria, dysuria or symptoms from the lower urinary tract. The patient did not demonstrate any laboratory signs of inflammation (white blood cells, C reactive protein). Scrotal sonography revealed a solid heterogeneous, hypoecoic lesion between the epididymal head and the upper testis pole, with disruption of the architecture of the testicular parenchyma. Strong ultrasound suspicion of tuberculous etiology was confirmed by epididymectomy and partial orchiectomy. The patient started an antitubercular treatment. Although rare, epididymal TB may be the only clinically evident location of infection. Clinical suspicion and prompt diagnosis are important because earlier treatment can prevent complications and lead to clinical improvement. PMID:24979105

  1. Nerve biopsy findings in two cases of Tangier disease

    Microsoft Academic Search

    R. S. Kocen; R. H. M. King; P. K. Thomas; L. F. Haas

    1973-01-01

    Nerve biopsy findings are recorded for two previously reported patients with Tangier disease (hereditary high density lipoprotein deficiency). Both cases showed unusual clinical manifestations in comparison with other reported cases. The neurological disorder, symptoms from which began in the third decade, gave rise to a lower motor neuron deficit of unique distribution, which was accompanied by progressive sensory impairment limited

  2. Theory of the unusual high-temperature anisotropic resistivity of underdoped iron arsenide superconductors: Evidence for an orbital nematic order

    Microsoft Academic Search

    M. S. Laad; L. Craco

    2011-01-01

    Recent finding of an unusual in-plane resistivity anisotropy in the underdoped 122 family at high temperature (T) suggests an orbital nematic (ON) order, posing a challenge to extant theories. The sign of the anisotropy contradicts expectations from weakly correlated as well as pure spin-only nematic views. Here, we show how such an ON order with accompanying structural distortion arises from

  3. Cardiac cone-beam CT

    SciTech Connect

    Manzke, Robert [University of London (King's College) (United Kingdom)]. E-mail: robert.manzke@philips.com

    2005-10-15

    This doctoral thesis addresses imaging of the heart with retrospectively gated helical cone-beam computed tomography (CT). A thorough review of the CT reconstruction literature is presented in combination with a historic overview of cardiac CT imaging and a brief introduction to other cardiac imaging modalities. The thesis includes a comprehensive chapter about the theory of CT reconstruction, familiarizing the reader with the problem of cone-beam reconstruction. The anatomic and dynamic properties of the heart are outlined and techniques to derive the gating information are reviewed. With the extended cardiac reconstruction (ECR) framework, a new approach is presented for the heart-rate-adaptive gated helical cardiac cone-beam CT reconstruction. Reconstruction assessment criteria such as the temporal resolution, the homogeneity in terms of the cardiac phase, and the smoothness at cycle-to-cycle transitions are developed. Several reconstruction optimization approaches are described: An approach for the heart-rate-adaptive optimization of the temporal resolution is presented. Streak artifacts at cycle-to-cycle transitions can be minimized by using an improved cardiac weighting scheme. The optimal quiescent cardiac phase for the reconstruction can be determined automatically with the motion map technique. Results for all optimization procedures applied to ECR are presented and discussed based on patient and phantom data. The ECR algorithm is analyzed for larger detector arrays of future cone-beam systems throughout an extensive simulation study based on a four-dimensional cardiac CT phantom. The results of the scientific work are summarized and an outlook proposing future directions is given. The presented thesis is available for public download at www.cardiac-ct.net.

  4. Urachal carcinoma: imaging findings

    PubMed Central

    Monteiro, Vanessa; Cunha, Teresa Margarida

    2012-01-01

    Urachal carcinoma is a rare neoplasm, which accounts for only 0.5–2% of bladder malignancies, and arises from a remnant of the fetal genitourinary tract. A 46-year-old woman presented with a history of pelvic pain and frequent daytime urination. Ultrasound (US), computed tomography (CT), and magnetic resonance (MR) demonstrated a supravesical heterogeneous mass with calcifications. The patient underwent a partial cystectomy with en-bloc resection of the mass and histopathological examination revealed the diagnosis of urachal adenocarcinoma. Urachal carcinomas are usually associated with poor prognosis and early diagnosis is fundamental. CT and MR are useful to correctly diagnose and preoperatively staging. PMID:23986824

  5. Classic and unusual appearances of hydatid disease in children

    Microsoft Academic Search

    Savvas Andronikou; Chris J. Welman; Ebrahim Kader

    2002-01-01

    Background. In endemic regions, hydatid disease is commoner in children than in adults. The hydatid cysts may have classic appearances, but unusual sites and appearances may cause diagnostic difficulties. Objective. To assess the classic and unusual appearances of hydatid disease in children. Materials and methods. A 3-year retrospective review of available imaging of proven hydatid disease at a tertiary paediatric

  6. 46 CFR 153.1020 - Unusually toxic cargoes.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Shipping 5 2010-10-01 2010-10-01 false Unusually toxic cargoes. 153.1020 Section 153.1020 Shipping COAST...Operations Special Cargo Procedures § 153.1020 Unusually toxic cargoes. (a) No person may load or carry a cargo...

  7. Characterization of Highly Unusual NH+ -O Hydrogen Bonding to

    E-print Network

    Lectka, Thomas

    Characterization of Highly Unusual NH+ -O Hydrogen Bonding to Ester Ether Oxygen Atoms through characterize a highly unusual, charged NH- O hydrogen bond formed within esters of 8-(dimethylamino)- naphthalen-1-ol in which an ammonium ion serves as an intramolecular hydrogen bond donor to spatially

  8. Unusual Foreign Body in Nose and Nasopharynx - A Rare Case

    PubMed Central

    Gannavarapu, Durga Prasad; Mukkamala, Achuta Narasimha Murty; K M, Jameel

    2015-01-01

    Lodgment of foreign body in the nose/nasopharynx in a sane adult person is unusual. Here, we present the case of a patient who came with an unusual foreign body (fish) lodged in the nose & nasopharynx. It was removed successfully in the outpatient department transorally with aid of nasal endoscopy. PMID:26023574

  9. [Diagnosis of fungal pneumonia in the thoracic CT].

    PubMed

    Heckmann, Martina; Uder, Michael; Bautz, Werner; Heinrich, Marc

    2008-01-01

    The importance of fungal infection of the lung in immunocompromised patients has increased substantially during the last decades. Numerically the most patients are those with neutropenia, e.g., patients with malignancies or solid organ and stem cell transplantation, chemotherapy, corticosteroid use and HIV infection. Although fungal infections can occur in immunocompetent patients, their frequency in this population is rare. The clinical symptoms such as fever accompanied with non-productive cough are unspecific. In some patients progression to hypoxemia and dyspnea may occur rapidly. In spite of improved antifungal therapy morbidity and mortality of these infections are still high. Therefore an early and non-invasive diagnosis is very important. That is why CT and even better High-Resolution-CT (HR-CT) is a very important modality in examining immunocompromised patients with a probability of fungal infection. CT is everywhere available and, as a non-invasive method, able to give the relevant diagnose efficiently. This paper should give an overview about the radiologic findings and possible differential diagnosis of diverse pulmonary fungal infections in CT. Pneumonias caused by Aspergillus, Cryptococcus, Candida, Histoplasma, Mucor and Geotrichum capitatum are illustrated. PMID:19294867

  10. Detection of relevant colonic neoplasms with PET\\/CT: promising accuracy with minimal CT dose and a standardised PET cut-off

    Microsoft Academic Search

    Wolfgang Luboldt; Teresa Volker; Bärbel Wiedemann; Klaus Zöphel; Ursula Wehrmann; Arne Koch; Todd Toussaint; Nasreddin Abolmaali; Markus Middendorp; Daniela Aust; Jörg Kotzerke; Frank Grünwald; Thomas J. Vogl; Hans-Joachim Luboldt

    2010-01-01

    Objective:  To determine the performance of FDG-PET\\/CT in the detection of relevant colorectal neoplasms (adenomas ?10 mm, with high-grade\\u000a dysplasia, cancer) in relation to CT dose and contrast administration and to find a PET cut-off.\\u000a \\u000a \\u000a \\u000a \\u000a Methods:  84 patients, who underwent PET\\/CT and colonoscopy (n?=?79)\\/sigmoidoscopy (n?=?5) for $${\\\\left( {{\\\\hbox{79}} \\\\times {\\\\hbox{6}} + {\\\\hbox{5}} \\\\times {\\\\hbox{2}}} \\\\right)} = {\\\\hbox{484}}$$ colonic segments, were included in a

  11. Recurrent pancreatic carcinoma and cholangiocarcinoma: 18 F-fluorodeoxyglucose positron emission tomography\\/computed tomography (PET\\/CT)

    Microsoft Academic Search

    Katherine Cameron; Sivan Golan; William Simpson; Steven Peti; Sasan Roayaie; Daniel Labow; Lale Kostakoglu

    Although the current literature is limited, available data suggest that 18F-fluorodeoxyglucose positron emission tomography\\/computed tomography (PET\\/CT) imaging improves the evaluation of patients\\u000a with recurrent pancreatic carcinoma and cholangiocarcinoma. There is evidence that PET\\/CT is particularly useful in the setting\\u000a of elevated tumor markers and negative or equivocal CT findings. This article reviews the nature of these carcinomas in the\\u000a post-therapy

  12. Unusual fan shaped ossification in a female fetus with radiological features of boomerang dysplasia

    PubMed Central

    Odent, S.; Loget, P.; Le Marec, B.; Delezoide, A.; Maroteaux, P.

    1999-01-01

    We report on a female fetus of 24 weeks whose clinical and radiological findings were compatible with boomerang dysplasia (BD). However, histopathology was unusual with a lateral fan shaped diaphyseal ossification. This has never been described either in typical atelosteogenesis I (AT-I) or in BD. The purpose of this report is to find out if this condition is a separate lethal bone dysplasia or another histological feature of the nosological group of AT-I and BD. ???Keywords: boomerang dysplasia; atelosteogenesis; lethal chondrodysplasia; lethal dwarfism PMID:10227404

  13. Serial volumetric registration of pulmonary CT studies

    NASA Astrophysics Data System (ADS)

    Silva, José Silvestre; Silva, Augusto; Sousa Santos, Beatriz

    2008-03-01

    Detailed morphological analysis of pulmonary structures and tissue, provided by modern CT scanners, is of utmost importance as in the case of oncological applications both for diagnosis, treatment, and follow-up. In this case, a patient may go through several tomographic studies throughout a period of time originating volumetric sets of image data that must be appropriately registered in order to track suspicious radiological findings. The structures or regions of interest may change their position or shape in CT exams acquired at different moments, due to postural, physiologic or pathologic changes, so, the exams should be registered before any follow-up information can be extracted. Postural mismatching throughout time is practically impossible to avoid being particularly evident when imaging is performed at the limiting spatial resolution. In this paper, we propose a method for intra-patient registration of pulmonary CT studies, to assist in the management of the oncological pathology. Our method takes advantage of prior segmentation work. In the first step, the pulmonary segmentation is performed where trachea and main bronchi are identified. Then, the registration method proceeds with a longitudinal alignment based on morphological features of the lungs, such as the position of the carina, the pulmonary areas, the centers of mass and the pulmonary trans-axial principal axis. The final step corresponds to the trans-axial registration of the corresponding pulmonary masked regions. This is accomplished by a pairwise sectional registration process driven by an iterative search of the affine transformation parameters leading to optimal similarity metrics. Results with several cases of intra-patient, intra-modality registration, up to 7 time points, show that this method provides accurate registration which is needed for quantitative tracking of lesions and the development of image fusion strategies that may effectively assist the follow-up process.

  14. Nonlesions, unusual cell types, and postmortem artifacts in the central nervous system of domestic animals.

    PubMed

    Wohlsein, P; Deschl, U; Baumgärtner, W

    2013-01-01

    In the central nervous system (CNS) of domestic animals, numerous specialized normal structures, unusual cell types, findings of uncertain or no significance, artifacts, and various postmortem alterations can be observed. They may cause confusion for inexperienced pathologists and those not specialized in neuropathology, leading to misinterpretations and wrong diagnoses. Alternatively, changes may mask underlying neuropathological processes. "Specialized structures" comprising the hippocampus and the circumventricular organs, including the vascular organ of the lamina terminalis, subfornical organ, subcommissural organ, pineal gland, median eminence/neurohypophyseal complex, choroid plexus, and area postrema, are displayed. Unusual cell types, including cerebellar external germinal cells, CNS progenitor cells, and Kolmer cells, are presented. In addition, some newly recognized cell types as of yet incompletely understood significance and functionality, such as synantocytes and aldynoglia, are introduced and described. Unusual reactive astrocytes in cats, central chromatolysis, neuronal vacuolation, spheroids, spongiosis, satellitosis, melanosis, neuromelanin, lipofuscin, polyglucosan bodies, and psammoma bodies may represent incidental findings of uncertain or no significance and should not be confused with significant microscopic changes. Auto- and heterolysis as well as handling and histotechnological processing may cause postmortem morphological changes of the CNS, including vacuolization, cerebellar conglutination, dark neurons, Buscaino bodies, freezing, and shrinkage artifacts, all of which have to be differentiated from genuine lesions. Postmortem invasion of micro-organisms should not be confused with intravital infections. Awareness of these different changes and their recognition are a prerequisite for identifying genuine lesions and may help to formulate a professional morphological and etiological diagnosis. PMID:22692622

  15. Ocular findings in trigonocephaly

    Microsoft Academic Search

    D. Denis; J. B. Saracco; L. Genitori; M. Choux; J. Bardot; I. H. Maumenee

    1994-01-01

    • Background: Trigonocephaly, caused by premature closure of the metopic suture, is a rare form of craniosynostosis. The aim of this study was to assess the visual outcome in children operated on for trigonocephaly • Methods: We present eight cases of children with trigonocephaly surgically corrected by the same craniofacial technique. CT with 3D reconstruction was performed in all cases.

  16. Bilateral adrenal gland haemorrhage: an unusual cause

    PubMed Central

    Shenoy, Vasant; Malabu, Usman; Cameron, Donald; Sangla, Kunwarjit

    2014-01-01

    Summary Our patient had drainage of a large amoebic liver abscess. This got complicated by a severe degree of hypotension, which required aggressive fluid resuscitation and hydrocortisone support. Computerised tomography (CT) of the abdomen revealed bilateral adrenal gland haemorrhage (BAH) resulting in primary adrenal gland failure, which was the cause for hypotension. Patient was on long-term warfarin for provoked deep vein thrombosis of lower limb, which was discontinued before the procedure. Thrombophilia profile indicated the presence of lupus anticoagulant factor with prolonged activated partial thromboplastin time (aPTT). Patient was discharged on lifelong warfarin. This case emphasises the need for strong clinical suspicion for diagnosing BAH, rare but life-threatening condition, and its association with amoebic liver abscess and anti-phospholipid antibody syndrome (APLS). Learning points Recognition of BAH as a rare complication of sepsis.APLS can rarely cause BAH. PMID:25276353

  17. An unusual aetiology for internuclear ophthalmoplegia

    PubMed Central

    Vishwas, Mellekate Shadaksharappa; Whitlow, Christopher T; Haq, Ihtsham ul

    2013-01-01

    Typical causes of internuclear ophthalmoplegia (INO) include arterial infarcts, demyelinating conditions, inflammation and trauma. We here report the unique case of a 33-year-old man with INO of the right eye caused by infarction of the right midbrain, confirmed by diffusion-weighted MRI. At presentation he displayed impaired adduction of the right eye with normal movement of the left. CT angiogram revealed an underlying developmental venous anomaly (DVA), raising the concern of venous infarction. His symptoms improved with aggressive management of blood pressure and risk factors. The patient had vascular risk factors—smoking, hypertension and dyslipidaemia—and we theorise that the hyalinised and inelastic walls of our patient's DVA were more vulnerable to the thrombogenic effects of his risk factors, predisposing him to this event. Venous infarcts owing to DVA are rare. To our knowledge INO secondary to venous infarct has not been reported, and should be considered in the differential of such cases. PMID:23737577

  18. Eyelid swelling, an unusual presentation of pneumomediastinum.

    PubMed

    Hwang, Richard Y; Rezaei, Kasra A; Melson, Mark R

    2014-01-01

    An 11-year-old girl with no significant medical or ocular history presented to the emergency department with asymmetrical eyelid swelling for 2 days. She was noted to have eyelid crepitus on examination. The patient reported a prolonged episode of crying followed by chest pain and dyspnea that resolved prior to her presentation. Both face and chest CT showed extensive air tracking in the subcutaneous tissues of the neck and face and pneumomediastinum without pneumothorax. The patient was discharged home without further intervention. On follow-up 1 to 2 weeks later, she had complete resolution of her symptoms. While pneumomediastinum is extremely rare in the pediatric population, it can be considered in the differential diagnoses of eyelid swelling and crepitus in the appropriate context. To this author's knowledge, this is the first pediatric case of pneumomediastinum with an initial presentation of eyelid swelling. PMID:24833458

  19. Colitis: an unusual presentation of Wegener's granulomatosis

    PubMed Central

    Sinnott, Joseph Dalby; Matthews, Paul; Fletcher, Simon

    2013-01-01

    Wegener's granulomatosis (WG) also known as granulomatosis with polyangiitis (GPA) is an anti-neutrophil cytoplasmic antibody-positive (ANCA) vasculitis which most commonly affects the upper respiratory tract, lungs and kidneys. It is uncommon for colitis to be the primary reason for the first hospital admission related to WG. This case represents one of the few in the literature where colitis is associated with WG and in particular, where colonic involvement was the presenting symptom. The patient presented to hospital with a 3-day history of bloody diarrhoea and was treated for colitis. The disease progressed and during the second admission renal and pulmonary involvement was found. A renal biopsy showed a crescentic change and a CT-confirmed inflammatory changes in the caecum and ascending colon. A diagnosis of WG was made and appropriate treatment initiated. The patient is now in remission. PMID:23436885

  20. Colitis: an unusual presentation of Wegener's granulomatosis.

    PubMed

    Sinnott, Joseph Dalby; Matthews, Paul; Fletcher, Simon

    2013-01-01

    Wegener's granulomatosis (WG) also known as granulomatosis with polyangiitis (GPA) is an anti-neutrophil cytoplasmic antibody-positive (ANCA) vasculitis which most commonly affects the upper respiratory tract, lungs and kidneys. It is uncommon for colitis to be the primary reason for the first hospital admission related to WG. This case represents one of the few in the literature where colitis is associated with WG and in particular, where colonic involvement was the presenting symptom. The patient presented to hospital with a 3-day history of bloody diarrhoea and was treated for colitis. The disease progressed and during the second admission renal and pulmonary involvement was found. A renal biopsy showed a crescentic change and a CT-confirmed inflammatory changes in the caecum and ascending colon. A diagnosis of WG was made and appropriate treatment initiated. The patient is now in remission. PMID:23436885

  1. Unusual case of a lung abscess.

    PubMed

    Musa, Duduzile; Godbole, Gauri; Chiodini, Peter L; Phillips, Russell

    2013-01-01

    A 56-year-old Caucasian lady presented with a short history of pleuritic chest pain on the background of a 2-month history of fever, chills, 10-kg weight loss and cough with brown sputum after a laparoscopic cholecystectomy. She had persistent eosinophilia and was diagnosed with a lung abscess as seen on chest x-ray. She did not respond to standard intravenous broad spectrum antibacterial medication and her chest CT scan showed a moderate pleural collection in continuity with the abscess. She also underwent bronchoscopy, the microscopy of the bronchial washings revealing eggs of the trematode Fasciola. The bacterial and fungal cultures of the washings were sterile. She had visited Turkey in the previous year but did not remember consuming any watercress or aquatic plants. She was successfully treated with two doses of the antiparasitic agent triclabendazole. Ectopic Fasciola can be a rare cause of a lung abscess. PMID:23595175

  2. Gradenigo Syndrome: Unusual Consequence of Otitis Media

    PubMed Central

    Valles, Jennie M.; Fekete, Robert

    2014-01-01

    Introduction In 1904, Giuseppe Gradenigo published his case series on the triad of ipsilateral abducens nerve palsy, facial pain in the trigeminal nerve distribution, and suppurative otitis media, which would subsequently be referred to as Gradenigo syndrome. Case Report Our patient was a 36-year-old female, 23 weeks pregnant, with a 6-day history of right-sided otalgia and hearing loss and a 4-day history of purulent otorrhea, who presented with severe, holocephalic headache, meningeal signs, fever, photophobia, and mental status decline. Lumbar puncture yielded a white blood cell count of 1,559 cells/mm3 with 95% polymorphonuclear leukocytes, a red blood cell count of 111 cells/mm3, a protein level of 61 mg/dl, and a glucose level of <40 mg/dl. Cerebrospinal fluid Gram stain showed Gram-positive diplococci, which were subsequently identified as Streptococcus pneumoniae and treated with ceftriaxone. On the second hospital day, she developed horizontal diplopia due to right abducens nerve palsy and right mydriasis. Both symptoms resolved on the third hospital day. Erosion of temporal bone and opacification of mastoid air cells was shown on CT scan. A CT venogram showed an irregularity of the left transverse and superior sagittal sinuses. She was treated with enoxaparin for possible sinus thrombosis. Discussion This case demonstrates rare but serious sequelae of otitis media and Gradenigo syndrome. Holocephalic headache from meningitis masked trigeminal pain. Involvement of the ipsilateral petrous apex and surrounding structures on imaging and clinical improvement with antibiotic treatment supports Gradenigo syndrome over intracranial hypertension due to venous sinus thrombosis as the cause of the abducens nerve palsy. PMID:25232331

  3. Etiology of Children's Diarrhea in Montevideo, Uruguay: Associated Pathogens and Unusual Isolates

    PubMed Central

    Torres, M. E.; Pírez, M. C.; Schelotto, F.; Varela, G.; Parodi, V.; Allende, F.; Falconi, E.; Dell'Acqua, L.; Gaione, P.; Méndez, M. V.; Ferrari, A. M.; Montano, A.; Zanetta, E.; Acuña, A. M.; Chiparelli, H.; Ingold, E.

    2001-01-01

    We studied microorganisms associated with infant diarrhea in a group of 256 children admitted to a public pediatric hospital in Montevideo, Uruguay. Diagnostic procedures were updated to optimize detection of potential pathogens, which were found in 63.8% of cases, and to be able to define their characteristics down to molecular or antigenic type. Coinfection with two or more agents was detected in more than one-third of positive studies. Escherichia coli enteric virotypes, especially enteropathogenic E. coli (EPEC), were shown to be prevalent. Rotavirus, Cryptosporidium, Campylobacter (mainly Campylobacter jejuni), and Shigella flexneri were also often identified. Enterotoxigenic E. coli, Salmonella, and Giardia lamblia were sporadically recognized. Unusual findings included two enteroinvasive E. coli strains, one Shigella dysenteriae 2 isolate, and a non-O:1 Vibrio cholerae culture. EPEC bacteria and S. flexneri (but not Salmonella) showed unusually frequent antimicrobial resistance, especially towards beta-lactam antibiotics, which is the subject of ongoing work. PMID:11376047

  4. Frequency of Incidental Findings on Computed Tomography of Trauma Patients

    PubMed Central

    Devine, Alicia S.; Jackson, Corinne S.; Lyons, Lisa; Mason, Jon D.

    2010-01-01

    Objective: To determine the incidence and frequency of follow-up instructions for incidental findings on computed tomography (CT) scanning of the abdomen and pelvis in trauma patients. Methods: We performed a retrospective chart review of all adult patients triaged to the trauma service at a Level I trauma center between July 1, 2003 and June 30, 2004. Included patients were 16 years of age and older who underwent abdomen and pelvic CT scans as part of their primary evaluation. We excluded patients under the age of 16 years, patients unable to complete radiographic studies due to deterioration in condition, patients with missing CT scan reports, and transferred patients who had CT scans done at outside facilities. Results: A total of 1,633 patients presented to the trauma service during the study period; 922 patients met inclusion criteria. Of these, 392 had incidental findings noted on the formal radiology report. Twenty patients with incidental findings either received additional workup during their hospital admission for their trauma injuries or were notified of the findings on discharge. Nine died prior to discharge. One hundred twenty-two patients with incidental findings had those findings noted in the history and physical or discharge summary with no documentation of follow-up. There was no documentation of any incidental findings in the electronic record for the majority of patients (242) with incidental findings. Conclusion: The majority of incidental findings discovered on abdomen and pelvic CT scanning of trauma patients are not documented; therefore, many patients may not receive the appropriate recommended follow up. PMID:20411070

  5. Finding overlapping images Finding overlapping images

    E-print Network

    Giger, Christine

    Finding overlapping images #12;Finding overlapping images · Close-range image sets are often unordered · no "natural" order of acquisition · no systematic block structure · How to find images to match? · obvious idea: try all pairs - does not scale to big projects · 1'000 images 499'500 pairs · 10'000 images

  6. Fluorine-18 fluorodeoxyglucose PET-CT for extranodal staging of non-Hodgkin and Hodgkin lymphoma

    PubMed Central

    Ömür, Özgür; Baran, Yusuf; Oral, Aylin; Ceylan, Ye?im

    2014-01-01

    PURPOSE We aimed to evaluate the role of fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT) involving care-dose unenhanced CT to detect extranodal involvement in patients with non-Hodgkin and Hodgkin lymphoma. MATERIALS AND METHODS Lymphoma patients (35 Hodgkin lymphoma, 75 non-Hodgkin lymphoma) who were referred for 18F-FDG PET-CT imaging, following a diagnostic contrast-enhanced CT (CE-CT) performed within the last month, were included in our study. A total of 129 PET-CT images, and all radiologic, clinical, and pathological records of these patients were retrospectively reviewed. RESULTS In total, 137 hypermetabolic extranodal infiltration sites were detected by 18F-FDG PET-CT in 62 of 110 patients. There were no positive findings by CE-CT that reflected organ involvement in 40 of 137 18F-FDG-positive sites. The ? statistics revealed fair agreement between PET-CT and CE-CT for the detection of extranodal involvement (?=0.60). The organs showing a disagreement between the two modalities were the spleen, bone marrow, bone, and thyroid and prostate glands. In all lesions that were negative at CE-CT, there was a diffuse 18F-FDG uptake pattern in the PET-CT images. The frequency of extranodal involvement was 51% and 58% in Hodgkin and non-Hodgkin lymphoma patients, respectively. There was a high positive correlation between the maximum standardized uptake values of the highest 18F-FDG-accumulating lymph nodes and extranodal sites (r=0.67) in patients with nodal and extranodal involvement. CONCLUSION 18F-FDG PET-CT is a more effective technique than CE-CT for the evaluation of extranodal involvement in Hodgkin and non-Hodgkin lymphoma patients. PET-CT has a significant advantage for the diagnosis of diffusely infiltrating organs without mass lesions or contrast enhancement compared to CE-CT. PMID:24412817

  7. PET/CT in radiation oncology

    SciTech Connect

    Pan, Tinsu; Mawlawi, Osama [Department of Imaging Physics, M. D. Anderson Cancer Center, University of Texas, Houston, Texas 77030 (United States)

    2008-11-15

    PET/CT is an effective tool for the diagnosis, staging and restaging of cancer patients. It combines the complementary information of functional PET images and anatomical CT images in one imaging session. Conventional stand-alone PET has been replaced by PET/CT for improved patient comfort, patient throughput, and most importantly the proven clinical outcome of PET/CT over that of PET and that of separate PET and CT. There are over two thousand PET/CT scanners installed worldwide since 2001. Oncology is the main application for PET/CT. Fluorine-18 deoxyglucose is the choice of radiopharmaceutical in PET for imaging the glucose uptake in tissues, correlated with an increased rate of glycolysis in many tumor cells. New molecular targeted agents are being developed to improve the accuracy of targeting different disease states and assessing therapeutic response. Over 50% of cancer patients receive radiation therapy (RT) in the course of their disease treatment. Clinical data have demonstrated that the information provided by PET/CT often changes patient management of the patient and/or modifies the RT plan from conventional CT simulation. The application of PET/CT in RT is growing and will become increasingly important. Continuing improvement of PET/CT instrumentation will also make it easier for radiation oncologists to integrate PET/CT in RT. The purpose of this article is to provide a review of the current PET/CT technology, to project the future development of PET and CT for PET/CT, and to discuss some issues in adopting PET/CT in RT and potential improvements in PET/CT simulation of the thorax in radiation therapy.

  8. CT of the gluteal region

    SciTech Connect

    Wechsler, R.J.; Schilling, J.F.

    1985-01-01

    Although the buttock can be involved in many pathologic processes, most physicians pay little attention to this area of the body. Because pelvic computed tomography (CT) delineates gluteal anatomy exquisitely, pathologic processes in the buttock are now frequently seen. Inflammation, neoplasm, or trauma involving the buttock may be difficult to differentiate without clinical history. However, spread of these processes to or from the pelvis or retroperitoneum is easily documented by CT. A number of these pathologic processes and the pathways of spread of disease involving the pelvis or retroperitoneum are described in this review.

  9. Low-dose interpolated average CT for attenuation correction in cardiac PET/CT

    NASA Astrophysics Data System (ADS)

    Wu, Tung-Hsin; Zhang, Geoffrey; Wang, Shyh-Jen; Chen, Chih-Hao; Yang, Bang-Hung; Wu, Nien-Yun; Huang, Tzung-Chi

    2010-07-01

    Because of the advantages in the use of high photon flux and thus the short scan times of CT imaging, the traditional 68Ge scans for positron emission tomography (PET) image attenuation correction have been replaced by CT scans in the modern PET/CT technology. The combination of fast CT scan and slow PET scan often causes image misalignment between the PET and CT images due to respiration motion. Use of the average CT derived from cine CT images is reported to reduce such misalignment. However, the radiation dose to patients is higher with cine CT scans. This study introduces a method that uses breath-hold CT images and their interpolations to generate the average CT for PET image attenuation correction. Breath-hold CT sets are taken at end-inspiration and end-expiration. Deformable image registration is applied to generate a voxel-to-voxel motion matrix between the two CT sets. The motion is equally divided into 5 steps from inspiration to expiration and 5 steps from expiration to inspiration, generating a total of 8 phases of interpolated CT sets. An average CT image is generated from all the 10 phase CT images, including original inhale/exhale CT and 8 interpolated CT sets. Quantitative comparison shows that the reduction of image misalignment artifacts using the average CT from the interpolation technique for PET attenuation correction is at a similar level as that using cine average CT, while the dose to the patient from the CT scans is reduced significantly. The interpolated average CT method hence provides a low dose alternative to cine CT scans for PET attenuation correction.

  10. Functional MRI and CT biomarkers in oncology.

    PubMed

    Winfield, J M; Payne, G S; deSouza, N M

    2015-04-01

    Imaging biomarkers derived from MRI or CT describe functional properties of tumours and normal tissues. They are finding increasing numbers of applications in diagnosis, monitoring of response to treatment and assessment of progression or recurrence. Imaging biomarkers also provide scope for assessment of heterogeneity within and between lesions. A wide variety of functional parameters have been investigated for use as biomarkers in oncology. Some imaging techniques are used routinely in clinical applications while others are currently restricted to clinical trials or preclinical studies. Apparent diffusion coefficient, magnetization transfer ratio and native T1 relaxation time provide information about structure and organization of tissues. Vascular properties may be described using parameters derived from dynamic contrast-enhanced MRI, dynamic contrast-enhanced CT, transverse relaxation rate (R2*), vessel size index and relative blood volume, while magnetic resonance spectroscopy may be used to probe the metabolic profile of tumours. This review describes the mechanisms of contrast underpinning each technique and the technical requirements for robust and reproducible imaging. The current status of each biomarker is described in terms of its validation, qualification and clinical applications, followed by a discussion of the current limitations and future perspectives. PMID:25578953

  11. 12 CFR 792.16 - What unusual circumstances can delay NCUA's response?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...16 What unusual circumstances can delay NCUA's response? (a) In unusual circumstances, the time limits for responding to your request...The unusual circumstances that can delay NCUA's response to your request...

  12. 12 CFR 792.16 - What unusual circumstances can delay NCUA's response?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...16 What unusual circumstances can delay NCUA's response? (a) In unusual circumstances, the time limits for responding to your request...The unusual circumstances that can delay NCUA's response to your request...

  13. 12 CFR 792.16 - What unusual circumstances can delay NCUA's response?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...16 What unusual circumstances can delay NCUA's response? (a) In unusual circumstances, the time limits for responding to your request...The unusual circumstances that can delay NCUA's response to your request...

  14. 12 CFR 792.16 - What unusual circumstances can delay NCUA's response?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...16 What unusual circumstances can delay NCUA's response? (a) In unusual circumstances, the time limits for responding to your request...The unusual circumstances that can delay NCUA's response to your request...

  15. 12 CFR 792.16 - What unusual circumstances can delay NCUA's response?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...16 What unusual circumstances can delay NCUA's response? (a) In unusual circumstances, the time limits for responding to your request...The unusual circumstances that can delay NCUA's response to your request...

  16. A Survey of Direct Users and Uses of SNOMED CT: 2010 Status

    PubMed Central

    Elhanan, Gai; Perl, Yehoshua; Geller, James

    2010-01-01

    SNOMED CT is gaining momentum and endorsements as an international clinical terminology. However, many vendors await a clearer business case and clients’ demand. We conducted a survey of direct users of SNOMED CT to determine the current profile of users, modes of use, and attitudes towards different aspects of the terminology. A web-base survey, consisting of 43 questions was distributed in January 2010, and 215 responses were elicited. This paper summarizes findings regarding profiles of users and their SNOMED CT use. The results indicate significant use by non-researchers and by industry and government sectors. Many users are relative newcomers with less than 3 years experience with SNOMED CT, and production-related use was reported by 39% of respondents. Most users are satisfied with the level of content coverage. The results indicate that SNOMED CT has a solid footing in production systems, and that SCT is mostly used for concept searches and clinical coding. PMID:21346970

  17. Opacification of the middle ear and mastoid: imaging findings and clues to differential diagnosis.

    PubMed

    Lo, A C C; Nemec, S F

    2015-05-01

    Opacification of the middle ear and mastoid represents a spectrum of inflammatory, neoplastic, vascular, fibro-osseous, and traumatic changes. This article reviews the most important clinical and pathological characteristics, emphasizing CT and MRI findings. Knowledge of subtle patterns of middle ear and mastoid opacification at CT and MRI provide guidance towards the correct diagnosis. PMID:25573814

  18. Case Series: Pericardial gossypibomas detected after cardiovascular surgery: Imaging findings

    PubMed Central

    Erol, Cengiz; Koplay, Mustafa; Paksoy, Yahya; Kanat, Fikret

    2012-01-01

    We present the chest radiograph, computed tomography (CT), and magnetic resonance imaging (MRI) findings of three pericardial gossypibomas, which are rarely reported and an exceptional complication of cardiovascular surgery. The diagnosis is usually possible with surgical history, high clinical suspicion, and awareness of variable imaging findings. Usage of sponges with radiopaque markers facilitates early detection by chest radiographs and CT. In case of radiolucent gossypibomas, specific MRI features help to differentiate this pathology from other masses and diffusion-weighted images can be used to distinguish it from an abscess. PMID:23833418

  19. Case Series: Pericardial gossypibomas detected after cardiovascular surgery: Imaging findings.

    PubMed

    Erol, Cengiz; Koplay, Mustafa; Paksoy, Yahya; Kanat, Fikret

    2012-10-01

    We present the chest radiograph, computed tomography (CT), and magnetic resonance imaging (MRI) findings of three pericardial gossypibomas, which are rarely reported and an exceptional complication of cardiovascular surgery. The diagnosis is usually possible with surgical history, high clinical suspicion, and awareness of variable imaging findings. Usage of sponges with radiopaque markers facilitates early detection by chest radiographs and CT. In case of radiolucent gossypibomas, specific MRI features help to differentiate this pathology from other masses and diffusion-weighted images can be used to distinguish it from an abscess. PMID:23833418

  20. Unusual inherent electrochemistry of graphene oxides prepared using permanganate oxidants.

    PubMed

    Eng, Alex Yong Sheng; Ambrosi, Adriano; Chua, Chun Kiang; San?k, Filip; Sofer, Zden?k; Pumera, Martin

    2013-09-16

    Graphene and graphene oxides are materials of significant interest in electrochemical devices such as supercapacitors, batteries, fuel cells, and sensors. Graphene oxides and reduced graphenes are typically prepared by oxidizing graphite in strong mineral acid mixtures with chlorate (Staudenmaier, Hofmann) or permanganate (Hummers, Tour) oxidants. Herein, we reveal that graphene oxides pose inherent electrochemistry, that is, they can be oxidized or reduced at relatively mild potentials (within the range ±1 V) that are lower than typical battery potentials. This inherent electrochemistry of graphene differs dramatically from that of the used oxidants. Graphene oxides prepared using chlorate exhibit chemically irreversible reductions, whereas graphene oxides prepared through permanganate-based methods exhibit very unusual inherent chemically reversible electrochemistry of oxygen-containing groups. Insight into the electrochemical behaviour was obtained through cyclic voltammetry, chronoamperometry, and X-ray photoelectron spectroscopy experiments. Our findings are of extreme importance for the electrochemistry community as they reveal that electrode materials undergo cyclic changes in charge/discharge cycles, which has strong implications for energy-storage and sensing devices. PMID:23934966

  1. Unusual manifestation of hepatic encephalopathy in two Irish wolfhound siblings.

    PubMed

    Herden, C; Beineke, A; Hetzel, U; Lemmer, W; Baumgärtner, W

    2003-11-29

    In hepatic encephalopathy the brain lesions are usually characterised by polymicrocavitation, preferentially in the white matter, and the occurrence of Alzheimer type II cells. This paper describes an unusual manifestation of hepatic encephalopathy in two Irish wolfhound siblings in which the white matter was not involved predominantly. Both puppies had developed progressive neurological disturbances and signs of blindness. Histologically, there were widespread spongiform changes in the neuropil and fibre bundles interspersed within the grey matter, and there were some neuronal vacuoles. In both animals, the regions of the brain mainly affected were the nucleus caudatus, amygdala, cerebellar nuclei, mesencephalon, thalamus, hypothalamus and medulla oblongata. An astrogliosis characterised by Alzheimer type II-like cells was also observed. Electron microscopy revealed a splitting of the myelin sheath. No infectious agents such as rabies virus, canine distemper virus or prion proteins were detected. The main findings in the portal regions of the liver consisted of a dilatation of the lymphatic vessels and increased numbers of small arteries, indicating that a portosystemic shunt was the probable cause of the spongiform brain lesions. PMID:14682542

  2. The unusual UBZ domain of Saccharomyces cerevisiae polymerase ?

    PubMed Central

    Woodruff, Rachel V.; Bomar, Martha G.; D’Souza, Sanjay; Zhou, Pei; Walker, Graham C.

    2010-01-01

    Recent research has revealed the presence of ubiquitin-binding domains in the Y family polymerases. The ubiquitin-binding zinc finger (UBZ) domain of human polymerase ? is vital for its regulation, localization, and function. Here, we elucidate structural and functional features of the non-canonical UBZ motif of S. cerevisiae pol ?. Characterization of pol ? mutants confirms the importance of the UBZ motif and implies that its function is independent of zinc binding. Intriguingly, we demonstrate that zinc does bind to and affect the structure of the purified UBZ domain, but is not required for its ubiquitin-binding activity. Our finding that this unusual zinc finger is able to interact with ubiquitin even in its apo form adds support to the model that ubiquitin binding is the primary and functionally important activity of the UBZ domain in S. cerevisiae polymerase ?. Putative ubiquitin-binding domains, primarily UBZs, are identified in the majority of known pol ? homologs. We discuss the implications of our observations for zinc finger structure and pol ? regulation. PMID:20837403

  3. Restrictive myocardium with an unusual pattern of apical hypertrophic cardiomyopathy.

    PubMed

    Sato, Takuma; Matsuyama, Taka-Aki; Seguchi, Osamu; Murata, Yoshihiro; Sunami, Haruki; Yanase, Masanobu; Fujita, Tomoyuki; Ishibashi-Ueda, Hatsue; Nakatani, Takeshi

    2015-01-01

    Loeffler endocarditis is a fibrous restrictive cardiomyopathy thought to be caused by persistent eosinophilia. It is difficult to diagnose, and the prognosis is often poor if the underlying eosinophilia is not promptly recognized and treated. We describe the case of a middle-aged woman treated for hypertrophic cardiomyopathy first detected during a routine check-up at age 35years but whose symptoms gradually progressed over the next 14years. Right ventricular biopsy showed extensive fibrosis of the endocardial tissue, and right heart catheterization revealed right heart failure and a low cardiac output state. Ultimately, she became reliant on inotropic and mechanical cardiovascular support, but we were not able to bridge her to transplant. Autopsy findings were typical of endocardial fibroelastosis, but she had not suffered from any tropical disease or traveled to high-risk areas. The presence of abnormal capillary proliferation suggested a diagnosis of Loeffler endocarditis. Nonetheless, apart from a 6-month period of eosinophilia 7years before her death, a history of well-controlled asthma and several drug sensitivities, we were unable to definitively identify the disease trigger. It is critical to diagnose and treat the underlying eosinophilia of Loeffler endocarditis to avoid a poor prognosis. This case highlights the importance of considering the diagnosis of eosinophilic endomyocarditis in patients with an unusual pattern of apical hypertrophic cardiomyopathy (or myocardial fibrosis of unknown etiology), even when there is no apparent history of eosinophilia. PMID:25804825

  4. An Unusual Stellar Death on Christmas Day

    NASA Technical Reports Server (NTRS)

    Thone, C. C.; de Ugarte Postigo, A.; Fryer, C. L.; Page, K. L.; Gorosabel, J.; Aloy, M. A.; Perley, D. A.; Kouveliotou, C.; Janka, H. T.; Mimica, P.; Racusin, J. L.; Krimm, H.; Cummings, J.; Oates, S. R.; Holland, S. T.; Siegel, M. H.; De Pasquale, M.; Sonbas, E.; Im, M.; Park, W. K.; Kann, D. A.; Guziy, S.; Hernandez Garcia, L.; Llorente, A.; Bundy, K.

    2011-01-01

    Long Gamma-Ray Bursts (GRBs) are the most dramatic examples of massive stellar deaths, usually associated with supernovae. They release ultra-relativistic jets producing non-thermal emission through synchrotron radiation as they interact with the surrounding medium. Here we report observations of the peculiar GRB 101225A (the "Christmas burst"). Its gamma-ray emission was exceptionally long and followed by a bright X-ray transient with a hot thermal component and an unusual optical couuterpart. During the first 10 days, the optical emission evolved as an expanding, cooling blackbody after which an additional component, consistent with a faint supernova, emerged. We determine its distance to 1.6 Gpc by fitting the spectral-energy distribution and light curve of the optical emission with a GRB-supernova template. Deep optical observations may have revealed a faint, unresolved host galaxy. Our proposed progenitor is a helium star-neutron star merger that underwent a common envelope phase expelling its hydrogen envelope. The resulting explosion created a GRB-like jet which gets thermalized by interacting with the dense, previously ejected material and thus creating the observed black-body, until finally the emission from the supernova dominated. An alternative explanation is a minor body falling onto a neutron star io the Galaxy

  5. Unusual Volcanic Pyroclastic Deposits on Io

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Four views of Euboea Fluctus on Jupiter's moon Io showing changes seen on June 27th, 1996 by the Galileo spacecraft as compared to views seen by the Voyager spacecraft during the 1979 flybys. Clockwise from upper left is a Voyager 1 high resolution image, a Galileo enhanced color image, a Galileo image with simulated Voyager colors, and a Voyager 2 color image. North is to the top of the picture. The Galileo images show new diffuse deposits which have an unusual morphology for plume deposits. A diffuse yellowish deposit with a radius of 285 km extends to the northwest, whereas an intense reddish deposit marks a curving fallout margin to the southeast. This morphology may have resulted from the presence of a topographic obstruction to southeast of the vent. The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC. This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

  6. SPECT-CT: applications in musculoskeletal radiology

    PubMed Central

    Burke, C; Desai, A; Vijayanathan, S; Gnanasegaran, G

    2013-01-01

    This article reviews the technique, basic science principles and applications of integrated single photon emission CT (SPECT)-CT in musculoskeletal radiology. A review of the current evidence on the topic was undertaken, and selected clinical cases from the authors' institution have been used for illustration. SPECT-CT is a technology with emerging applications that offers technical advantages to image fusion of separately acquired SPECT and CT studies. The prevailing evidence indicates that there may be benefit in adding SPECT-CT to conventional imaging algorithms during the evaluation of some malignant and benign musculoskeletal conditions. SPECT-CT can improve both sensitivity and specificity by reducing equivocal interpretation in comparison to planar scintigraphy or SPECT alone. The evidence base for SPECT-CT in musculoskeletal radiology is still evolving. There is a lack of evidence comparing SPECT-CT with MRI in many key indications, and further research is required in these areas. PMID:24096590

  7. CT diagnosis of hernia of Morgagni

    Microsoft Academic Search

    Donald Fagelman; James G. Caridi

    1984-01-01

    A single case of hernia of Morgagni diagnosed by computed tomography (CT) is presented. CT is an accurate, noninvasive method of evaluating this entity and can replace many of the other imaging modalities previously employed.

  8. Pocket atlas of normal CT anatomy

    SciTech Connect

    Weinstein, J.B.; Lee, J.K.T.; Sagel, S.S.

    1985-01-01

    This book is a quick reference for interpreting CT scans of the extracranial organs. This collection of 41 CT scans covers all the major organs of the body: neck and larynx; chest; abdomen; male pelvis; and female pelvis.

  9. Evaluation of Mediastinal Lymph Nodes in Sarcoidosis, Sarcoid Reaction, and Malignant Lymph Nodes Using CT and FDG-PET/CT.

    PubMed

    Koo, Hyun Jung; Kim, Mi Young; Shin, So Youn; Shin, Sooyoung; Kim, Sung-Soo; Lee, Sei Won; Choi, Chang-Min

    2015-07-01

    The aim of this study was to analyze the clinical, computed tomography (CT), and positron emission tomography (PET) findings of sarcoidosis, sarcoid reaction, and malignant lymph nodes (LNs) to the results of transbronchial LN aspiration and biopsy (TBNA).The TBNA results of mediastinal and hilar LNs of 152 patients in our hospital from July 2008 to March 2013 were retrospectively reviewed. Two independent radiologists measured the size and attenuation of LNs on CT and assessed the probability of the 3 categories: sarcoidosis (n?=?36), sarcoid reaction (n?=?25), or malignant LNs (n?=?91). The total volume and attenuation of LNs were measured using Image J (NIH). The median maximum standardized uptake value (maxSUV) of the 3 mediastinal and hilar LNs on PET/CT was obtained.There was no significantly different CT finding between sarcoidosis and sarcoid reaction. Multivariate analysis showed that the age, total volume of LNs, and number of enlarged LNs significantly differed between sarcoid reaction and malignant LNs. Sarcoid reaction tends to be occurred in young patients (P?=?0.007), the total volume of LNs was smaller (P?=?0.04) than that of malignant LNs, and there were significantly more LNs >1?cm (P?=?0.005). The median maxSUV of the 3 highest SUVs of the LNs did not significantly differ between the 3 entities. PMID:26166096

  10. The diagnostic accuracy of preoperative CT scanning in the evaluation of pituitary ACTH-secreting adenomas.

    PubMed

    Marcovitz, S; Wee, R; Chan, J; Hardy, J

    1987-10-01

    Between 1980 and 1985, 35 patients (26 women and nine men) who had coronal CT scans of the sella turcica for suspected ACTH-secreting pituitary adenoma underwent transsphenoidal exploration. The CT examinations were performed with a fourth-generation EMI scanner (CT 7070). The reports of the preoperative CT examinations were compared with the findings at transsphenoidal exploration; in cases with negative CT scans, the decision to operate was based on biochemical evidence of Cushing's disease. In 27 patients, distinct adenomas were found at surgery; in the eight others, total hypophysectomy (four cases) or resection of the central core of the pituitary gland (four cases) was performed. Three patients had macroadenomas, all of which had been identified correctly on preoperative CT scan. Among the 24 microadenomas (less than 10 mm diameter), 14 had been correctly identified on preoperative CT scan while 10 were found in patients with negative scans. The CT examinations in these 35 patients showed probable adenomas in 20 cases, of which 17 (85%) were confirmed at surgery. In the other three cases (15%), adenomas were not found. Among the 15 patients with negative CT scans, 10 (66.6%) had distinct adenomas found at surgery. Coronal CT scans for ACTH-secreting adenomas had a sensitivity of 63%, a specificity of 62.5%, and an overall accuracy rate of 62.8%. Thus, in our experience, CT scanning with current state-of-the-art equipment has poor diagnostic accuracy in Cushing's disease. The possible reasons for this are that most of the adenomas in this series were microadenomas less than 6 mm in diameter, and that ACTH microadenomas probably show almost the same degree of enhancement with contrast medium as the surrounding normal pituitary tissue. PMID:2820217

  11. CT diagnosis and staging of pancreatic carcinoma.

    PubMed

    Freeny, Patrick C

    2005-11-01

    The current use of multidector row helical CT (MDCT) and imaging postprocessing techniques represents an additional step forward in the use of helical CT for detection and staging of pancreatic carcinoma. Although no large series have been published detailing the accuracy of MDCT compared to single detector row helical CT, the additional resolution of the MDCT thin-section images and use of postprocessing techniques should certainly equal, if not exceed, the accuracy of the helical CT. PMID:16479656

  12. An Aneurysm of the CervicalVertebral Artery Causing Radiculopathy—An UnusualCase

    Microsoft Academic Search

    Wolfgang Börm; Gregor Antoniadis; Alexander Müller; Hans-Peter Richter

    2003-01-01

    Case Report: We report on a 37-year-old woman with a 10-week history of neck pain and brachialgia along the right C6 dermatome. Neurological findings included weakness of the right biceps muscle and hypesthesia of the right thumb. The patient was diagnosed as having von Recklinghausen’s disease (neurofibromatosis 1) 10 years ago, and a CT scan demonstrated an extraspinal paravertebral mass

  13. An unusual nasopharyngeal foreign body with unusual presentation as nasal regurgitation and change in voice.

    PubMed

    Kumar, Sunil; Singh, Devendra Bahadur; Singh, Abhishek Bahadur

    2013-01-01

    Upper aerodigestive tract may harbour foreign bodies such as sponges, grains, toy parts, stones, paper, insects, cotton, etc. These objects may go undetected for days or even weeks. A metallic foreign body after being inhaled and ultimately being lodged in the nasopharynx is a rare entity. We report a case of an unusual nasopharyngeal foreign body (metallic bolt) presenting with symptoms of nasal regurgitation and change in voice in a 2-year boy. The foreign body was diagnosed by X-ray skull lateral view including nasopharynx and was removed under general anaesthesia. PMID:23884977

  14. CT Localization in Stereotactic Surgery

    Microsoft Academic Search

    J. Boëthius; M. Bergström; T. Greitz; T. Ribbe

    1980-01-01

    A stereotactic system is described. It is built around a baseplate which is fastened to the head of the patient and to various diagnostic and therapeutic modalities. In principle this system can function as an interface between most diagnostic (CT scanners, PET scanners, conventional X-ray instrumentation for angiograms and pneumoencephalograms) and therapeutic (stereotactic instruments, linear accelerators) instruments. It has been

  15. [Transabdominal CT-guided sympathectomy].

    PubMed

    Schild, H; Grönniger, J; Günther, R; Thelen, M; Schwab, R

    1984-11-01

    A new technique for lumbar sympathectomy is described. It consists of CT-guided trans-abdominal fine needle puncture and injection of alcohol. The technique is simple and well tolerated by the patient, and it permits accurate application of the alcohol. Complications have so far not been observed. PMID:6438713

  16. Unusual persistence of DDT in some western USA soils

    SciTech Connect

    Hitch, R.K.; Day, H.R. (Environmental Protection Agency, Washington, DC (United States))

    1992-02-01

    Agricultural use of DDT (1,1,1-trichloro-2,2,2-bis (p-chlorophenyl) ethane) was canceled in 1972. By the late 1970's and early 1980's, the National Soils Monitoring Program of the US Environmental Protection Agency (EPA) was consistently finding higher soil residues of the degradate DDE (1,1-dichloro 2,2-bis (p-chlorophenyl) ethylene) than of parent DDT. Similarly, the US Fish and Wildlife Service (FWS) had been finding during the late 1970's that DDT and related compounds had been decreasing in birds throughout the US. During 1984 and 1985, the EPA and the agriculture departments of Texas and New Mexico, in response to the FWS, conducted soil sampling in 13 areas where contaminated birds had been collected. It was agreed that soil samples containing higher levels of DDT than DDE would serve as a possible indicator of illegal DDT use. This was an intensive soil sampling program; over 236 fields were sampled. A controversy developed as to whether high ratios of DDT and DDE might corroborate the accusations of recent illegal use of DDT products. Dell City area soils containing higher levels of DDT than of DDE became classified as suspicious soils. Soils bearing the expected higher level of DDE were dubbed as normal. To resolve the controversy, the authors, in 1989, conducted a DDT soil metabolism study with representative samples of the suspicious and normal soils. It was felt that a soil metabolism study could, once and for all, determine if there was, indeed, something unusual about the rate at which the suspicious soils degrade DDT.

  17. Experimental assessment of CT-based thermometry during laser ablation of porcine pancreas

    NASA Astrophysics Data System (ADS)

    Schena, E.; Saccomandi, P.; Giurazza, F.; Caponero, M. A.; Mortato, L.; Di Matteo, F. M.; Panzera, F.; Del Vescovo, R.; Beomonte Zobel, B.; Silvestri, S.

    2013-08-01

    Laser interstitial thermotherapy (LITT) is employed to destroy tumors in organs, and its outcome strongly depends on the temperature distribution inside the treated tissue. The recent introduction of computed tomography (CT) scan thermometry, based on the CT number dependence of the tissue with temperature, overcomes the invasiveness of other techniques used to monitor temperature during LITT. The averaged CT number (ROI = 0.02 cm2) of an ex vivo swine pancreas is monitored during LITT (Nd:YAG laser power of 3 W, treatment time: 120 s) at different distances from the applicator (from 4 to 30 mm). The averaged CT number shows a clear decrease during treatment: it is highest at 4 mm from the applicator (mean variation in the whole treatment of -0.256 HU s-1) and negligible at 30 mm, since the highest temperature increase is present close to the applicator (i.e., 45 °C at 4 mm and 25 °C at 6 mm). To obtain the relationship between CT numbers and pancreas temperature, the reference temperature was measured by 12 fiber Bragg grating sensors. The CT number decreases as a function of temperature, showing a nonlinear trend with a mean thermal sensitivity of -0.50 HU °C-1. Results here reported are the first assessment of pancreatic CT number dependence on temperature, at the best of our knowledge. Findings can be useful to further investigate CT scan thermometry during LITT on the pancreas.

  18. Interactive Exploration of Large Remote -CT Scans

    E-print Network

    Prohaska, Steffen

    Interactive Exploration of Large Remote µ-CT Scans Steffen Prohaska · Andrei Hutanu Ralf Kähler. The sheer size of the micro CT scans make them difficult to handle. [NEXT SLIDE] We decided to handle them... #12;local data acquisition central storage Internet µ-CT Scans 8 GB per dataset [cont.] We decided

  19. CT Innovators Reunion: Where Are They Now?

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2012-01-01

    Each year, "Campus Technology" ("CT") gazes across higher ed horizons to identify the most innovative IT programs at colleges and universities around the globe. The projects "CT" profiles are inspiring examples of technology making a difference on campus--at least at that moment. The question is, have they stood the test of time? "CT" followed up…

  20. Calibrator Blocks For Computerized Tomography (CT)

    NASA Technical Reports Server (NTRS)

    Engel, H. Peter

    1990-01-01

    Sets of calibrator blocks developed for use with industrial computerized tomography (CT) systems. Set of blocks (or number of stacked sets of blocks) placed on object table of CT system and scanned in usual way. Blocks include holes of known size, shape, and location. Appearance of holes in output image of CT system used to verify operation of system.

  1. CT Colonography of Colorectal Polyps: A Metaanalysis

    Microsoft Academic Search

    Jacob Sosna; Martina M. Morrin; Jonathan B. Kruskal; Philip T. Lavin; Max P. Rosen; Vassilios Raptopoulos

    OBJECTIVE. For proper evaluation of the accuracy of CT colonography, prospective multiinstitutional trials would be ideal. Until these trials are available, data can be collectively analyzed. The purpose of this study is to use metaanalysis to assess the reported accuracy of CT colonography compared with conventional colonoscopy for detecting colorectal polyps. MATERIALS AND METHODS. Articles comparing CT colonography and conven-

  2. CT diagnosis and staging of pancreatic carcinoma

    Microsoft Academic Search

    Patrick C. Freeny

    2005-01-01

    The current use of multidector row helical CT (MDCT) and imaging postprocessing techniques represents an additional step forward in the use of helical CT for detection and staging of pancreatic carcinoma. Although no large series have been published detailing the accuracy of MDCT compared to single detector row helical CT, the additional resolution of the MDCT thin-section images and use

  3. Posttreatment assessment of response using FDG-PET/CT for patients treated with definitive radiation therapy for head and neck cancers

    SciTech Connect

    Andrade, Regiane S. [Department of Radiation Oncology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States); Heron, Dwight E. [Department of Radiation Oncology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States)]. E-mail: HeronD2@upmc.edu; Degirmenci, Berna [Division of Nuclear Medicine, Department of Radiology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States); Filho, Pedro A.A. [Department of Otolaryngology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States); Branstetter, Barton F. [Division of Neuroradiology, Department of Radiology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States); Department of Otolaryngology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States); Seethala, Raja R. [Department of Pathology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States); Ferris, Robert L. [Department of Otolaryngology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States); Avril, Norbert [Division of Nuclear Medicine, Department of Radiology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States)

    2006-08-01

    Purpose: The goal of this study was to evaluate coregistered [{sup 18}F] fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) for the detection of persistent disease after definitive radiation therapy in head and neck cancer. Methods and Materials: Posttreatment FDG-PET/CT was performed in 28 patients on average 8 weeks (range, 4 to 15.7 weeks) after completing definitive radiation therapy. FDG-PET/CT was visually analyzed for the entire patient group and at two time points (4-8 and >8 weeks) after treatment. The contrast-enhanced CT portion of PET/CT was separately analyzed blinded to the results of coregistered FDG-PET/CT and classified as negative or positive for residual locoregional disease. Pathologic findings and clinical follow-up served as the reference standard. Results: Follow-up data were available for all 28 patients (median, 17.6 months). Regarding the detection of residual disease, the overall sensitivity and specificity of FDG-PET/CT was 76.9% and 93.3%, respectively, compared with 92.3% and 46.7% for contrast-enhanced CT. The accuracy of FDG-PET/CT was 85.7%, compared with 67.9% for CT alone. All false-negative (n = 3) and false-positive (n = 1) FDG-PET/CT results occurred between 4 and 8 weeks after treatment. At 8 weeks or later after treatment, the specificity of CT was 28%, compared with 100% for FDG-PET/CT. Conclusions: The metabolic-anatomic information from coregistered FDG-PET/CT provided the most accurate assessment for treatment response when performed later than 8 weeks after the conclusion of radiation therapy. FDG-PET/CT excelled by a higher specificity and overall diagnostic performance than CT imaging alone. These results support a potential clinical role of FDG-PET/CT in the early assessment of therapy response after definitive radiation therapy.

  4. A radiation exposure index for CT.

    PubMed

    Huda, Walter

    2013-12-01

    The purpose of this study is to define an Exposure Index for CT (EI(CT)) and to estimate the magnitude of the EI(CT) for common clinical CT examinations. For a single-axial rotation of a CT X-ray tube that includes only rays that pass through the patient, the CT Exposure Index (EI(CT)) is defined as the average Air Kerma that would be incident on an extended 360° detector array completely surrounding the patient. For an axial scan of a uniform cylindrical phantom, EI(CT) can be approximated as T × [(CTDI(air))/4] × [?°/360°] where T is the fractional transmission through the cylinder, CTDI(air) is the CT Dosimetry Index-determined 'free in air' at isocentre, and ?/2 is the fan beam angle that will completely irradiate a cylindrical phantom at isocentre. The value of CTDI(air) can be estimated from the weighted CTDI (CTDI(w)) for a given CT examination, and the angle ? depends on the irradiation geometry that can be obtained from the cylinder diameter (r) and the focus to isocentre distance (R). At a voltage of 120 kV, transmission through an adult head was ?2.6%, through an adult abdomen?0.4% and through a 5-y-old paediatric abdomen ?3%. Average ratios of CTDI(air)/CTDI(w) were 1.42 ± 0.12 in 16-cm dosimetry phantom and 2.82 ± 0.37 in 32-cm phantom. Values of ? ranged from 30.1° (R = 61 cm and r=8 cm) to 85.3° (R = 55 cm and r=20 cm). For an adult head CT examination, EI(CT) was estimated to be?70 µGy at a CTDI(vol) of 75 mGy (16 cm), and for an adult abdominal CT examination, EI(CT) was estimated to be?11 µGy at a CTDI(vol) of 25 mGy (32 cm). For an abdomen CT examination in a 5-y-old child, EI(CT) was estimated to be ?21 µGy at a CTDI(vol) of 20 mGy (16 cm). The EI(CT) is introduced that provides a quantitative measure of the amount of the radiation used to generate images in any CT examination and is analogous to the average image receptor Exposure Index recently proposed for use in projection imaging. The EI(CT) metric provides operators with an objective index of the amount of the radiation used to create CT images and can be used to control quantum mottle in CT. PMID:23690648

  5. Unusually severe case of dermatosis neglecta.

    PubMed

    Turrentine, Jake E; Blalock, Travis W; Davis, Loretta S

    2012-01-01

    An 18-year-old black woman with cerebral palsy was admitted for evaluation of an intrathecal baclofen pump site infection. The dermatology service was consulted for treatment suggestions of a presumed diagnosis of chronic tinea capitis. Three courses of oral griseofulvin during the past 2 years failed to resolve the patient's chronic scalp dermatosis. Scalp lesions first began about 2 years earlier after hospitalization for placement of an intrathecal baclofen pump. The patient was unable to care for her scalp due to her cerebral palsy, and her mother interpreted the scalp condition as infectious. No routine shampoo care, scalp care, or topical treatment was performed for more than 1 1/2 years. The mother felt that touching the patient's scalp might cause pain and noted that the majority of her time was spent concentrating on more critical medical issues. Physical examination revealed coalescing hyperkeratotic plaques extending dorsally from the anterior hairline to the occipital scalp with small flecks of keratinous debris throughout the remaining hair (Figure 1). The plate-like plaques were devoid of hair, except at a few fissures where a few tufts of hair emerged. No cervical lymph nodes were appreciated on palpation. Treatment was initiated with compresses consisting of large warm water-soaked towels 4 times daily. Three times a day, a nursing staff applied 5% salicylic acid in olive oil to the scalp under a shower cap for approximately 1 hour. Over the following 2 days, a significant reduction in keratinous debris was appreciated. Within 2 weeks, the bulk of the plaques had been removed (Figure 2). At 6-week follow-up, the underlying scalp showed areas of fibrosis and possible scarring with a few emerging tufts of hair. On the basis of history and response to treatment with salicylic acid and routine scalp care, the patient was diagnosed with an unusually severe case of dermatosis neglecta. PMID:22324178

  6. Solitary Splenic Metastasis From Hepatocellular Carcinoma Detected on 18F-FDG PET/CT.

    PubMed

    Kim, Do-Hoon; Jeong, Shin Young; Lee, Sang-Woo; Lee, Jaetae; Ahn, Byeong-Cheol

    2015-06-01

    We report a case of solitary splenic metastasis from hepatocellular carcinoma detected on F-FDG PET/CT. A 67-year-old man with hepatocellular carcinoma was referred for F-FDG PET/CT to determine the cause of his elevated serum ?-fetoprotein levels after liver segmentectomy and radio-frequency ablation. F-FDG PET/CT imaging showed focal FDG uptake in the spleen, with no other abnormal findings. A splenectomy was performed, and histopathologic examination confirmed the lesion as a metastasis from the hepatocellular carcinoma. PMID:25546205

  7. Multi-Slice Spiral CT of Living-Related Liver Transplantation in Children: Pictorial Essay

    PubMed Central

    Choi, Seong Hoon; Yoon, Chong Hyun

    2004-01-01

    In pediatric living-related liver transplantation, preoperative evaluation of the recipient is important for surgical planning, while the accurate diagnosis of postoperative complications is essential for graft salvage. Multiplanar and three-dimensional imaging using multi-slice spiral CT can be used for preoperative vascular imaging, as well as for evaluating postoperative complications. In this essay, we describe the usefulness of multi-slice CT, combined with a variety of different reconstruction techniques, for the preoperative evaluation of transplant recipients. In addition, we demonstrate the multi-slice CT findings of postoperative complications, including vascular stenosis or thrombosis, bile duct leak or stricture, and extrahepatic fluid collection. PMID:15467417

  8. Unusual forms of halloysite in a Guatemalan soil 

    E-print Network

    Askenasy, Pablo Ernesto

    1971-01-01

    ) August 1871 ABSTRACT Unusual Porms of IIalloysitc in a Guatemalan Soil (August. 1971) Pablo Ernesto Askenasy, B. S. , Texas ASM University Directed by: Dr. Joe B. Dixon Alotenango clay subsoil of volcanic origin was di. spersed and fraction...

  9. 48 CFR 232.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 232.501-2 Unusual progress payments. Follow the procedures at PGI 232.501-2 for...

  10. 48 CFR 1332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1332.501-2 Unusual progress payments. The designee authorized to approve a...

  11. 48 CFR 932.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 932.501-2 Unusual progress payments. (a)(3) For DOE, the Head of the...

  12. 48 CFR 32.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 32.501-2 Unusual progress payments...documents an actual need to supplement any private financing available, including guaranteed loans;...

  13. 48 CFR 1332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1332.501-2 Unusual progress payments. The designee authorized to approve a...

  14. 48 CFR 1332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1332.501-2 Unusual progress payments. The designee authorized to approve a...

  15. 48 CFR 932.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 932.501-2 Unusual progress payments. (a)(3) For DOE, the Head of the...

  16. 48 CFR 32.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 32.501-2 Unusual progress payments...documents an actual need to supplement any private financing available, including guaranteed loans;...

  17. 48 CFR 232.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 232.501-2 Unusual progress payments. Follow the procedures at PGI 232.501-2 for...

  18. 48 CFR 932.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 932.501-2 Unusual progress payments. (a)(3) For DOE, the Head of the...

  19. 48 CFR 232.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 232.501-2 Unusual progress payments. Follow the procedures at PGI 232.501-2 for...

  20. 48 CFR 232.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 232.501-2 Unusual progress payments. Follow the procedures at PGI 232.501-2 for...

  1. 48 CFR 1332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1332.501-2 Unusual progress payments. The designee authorized to approve a...

  2. 48 CFR 1432.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1432.501-2 Unusual progress payments. The CO shall obtain the advance approval of the...

  3. 48 CFR 332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Cost 332.501-2 Unusual progress payments. (a)(3) The HCA (non-delegable) shall...

  4. 48 CFR 32.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 32.501-2 Unusual progress payments...documents an actual need to supplement any private financing available, including guaranteed loans;...

  5. 48 CFR 32.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 32.501-2 Unusual progress payments...documents an actual need to supplement any private financing available, including guaranteed loans;...

  6. 48 CFR 332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Cost 332.501-2 Unusual progress payments. (a)(3) The HCA (non-delegable) shall...

  7. 48 CFR 1432.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1432.501-2 Unusual progress payments. The CO shall obtain the advance approval of the...

  8. 48 CFR 332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Cost 332.501-2 Unusual progress payments. (a)(3) The HCA (non-delegable) shall...

  9. 48 CFR 32.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 32.501-2 Unusual progress payments...documents an actual need to supplement any private financing available, including guaranteed loans;...

  10. 48 CFR 1332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1332.501-2 Unusual progress payments. The designee authorized to approve a...

  11. 48 CFR 932.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 932.501-2 Unusual progress payments. (a)(3) For DOE, the Head of the...

  12. 48 CFR 932.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 932.501-2 Unusual progress payments. (a)(3) For DOE, the Head of the...

  13. 48 CFR 1432.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1432.501-2 Unusual progress payments. The CO shall obtain the advance approval of the...

  14. 48 CFR 332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Cost 332.501-2 Unusual progress payments. (a)(3) The HCA (non-delegable) shall...

  15. 48 CFR 232.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 232.501-2 Unusual progress payments. Follow the procedures at PGI 232.501-2 for...

  16. 48 CFR 1432.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1432.501-2 Unusual progress payments. The CO shall obtain the advance approval of the...

  17. 48 CFR 332.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Cost 332.501-2 Unusual progress payments. (a)(3) The HCA (non-delegable) shall...

  18. 48 CFR 1432.501-2 - Unusual progress payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress Payments Based on Costs 1432.501-2 Unusual progress payments. The CO shall obtain the advance approval of the...

  19. NASA Reveals Most Unusual Planet - Duration: 31 seconds.

    NASA Video Gallery

    In exploring the universe, NASA has uncovered one planet more unusual than all others. This 30 second video shows you which planet that is, and explains that NASA science helps us better understand...

  20. Neutron scattering investigations on the unusual phase behavior of water

    E-print Network

    Zhang, Yang, Ph. D. Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering

    2010-01-01

    Water is the most ubiquitous substance on earth, and is essential to sustain all known forms of life. However, despite centuries of research, a coherent picture of the unusual phase behavior of water is so far lacking. The ...