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1

Presumed primary muscular lymphoma in a dog.  

PubMed

A case of presumed primary muscular lymphoma in an 8-year-old, intact, male Newfoundland dog is reported. The dog was presented for evaluation of an infiltrating ventral cervical mass, respiratory distress, and anorexia of 1-month duration. Fine-needle aspiration of the mass revealed anaplastic large cell lymphoma. Despite chemotherapy, health status declined and the animal was euthanized a few weeks later. At necropsy, the mass infiltrated the cervical muscles and extended ventrally to the left forelimb and cranially to the tongue and laryngeal musculature. Other muscles were infiltrated by the same neoplasm (diaphragm and intercostal, abdominal, and gluteal muscles) indicating a probable multicentric origin. Histological examination confirmed the diagnosis of anaplastic large cell lymphoma, which showed a strong muscular tropism. Immunohistochemical staining revealed neoplastic cell reactivity for cluster of differentiation 3 (CD3) and Ki-67 antigens (70% and 90%, respectively). The neoplastic cells were negative for CD79a. The presumed histological diagnosis in this dog was primary muscular anaplastic large T-cell lymphoma. PMID:18987239

Thuilliez, Céline; Watrelot-Virieux, Dorothée; Chanut, Franck; Fournel-Fleury, Corinne; Ponce, Frédérique; Marchal, Thierry

2008-11-01

2

Prevalence of immunity presumed using rabies vaccination history and household factors associated with vaccination status among domestic dogs in Japan.  

PubMed

Rabies was eliminated in Japan over 50 years ago; however, the recent increase in the movement of humans and animals across the world highlights the potential threat of disease reentry into the country. The immune status against rabies among the dog population in Japan is not well known; thus, the purpose of this study was to estimate the prevalence of dogs with effective immunity from the vaccination history using a web-based survey. We found that 76.9% (95% confidence interval, 75.8-78.1) of dogs in this study population belonged to the population in which 90% were assumed to have the internationally accepted antibody titer. We showed that dogs taken less frequently for walks were less likely to be vaccinated. Additionally, the frequency of encounters with other dogs during walks and the number of individuals in households were associated with vaccination history. To our knowledge, this study is the first report estimating the prevalence of dogs in Japan with effective immunity against rabies. Further, we identified the population with low vaccination coverage as well as the heterogeneous characteristics of vaccination history among the dog population. These findings contribute to the implementation of an efficient strategy for improving the overall vaccination coverage in Japan and the development of a quantitative risk assessment of rabies. PMID:22996212

Hidano, Arata; Hayama, Yoko; Tsutsui, Toshiyuki

2012-01-01

3

Viral vector-mediated RNA interference.  

PubMed

RNA interference (RNAi) is a powerful gene silencing mechanism that if properly harnessed has the potential to revolutionize medical interventions. Delivery of inhibitory RNAs to target tissues needs to be safe, efficient, and for many diseases, long-lasting, in order to exploit this endogenous mechanism for therapeutic purposes. Viral vector systems, based on adeno-associated viruses and lentiviruses, are ideally suited to mediate RNAi because they can safely transduce a wide range of tissues and provide sustained levels of gene expression. There are now many examples of the use of viral vector-mediated RNAi to inhibit gene expression in animal models of disease, and in many cases proof-of-principle has been demonstrated. The efficient delivery of RNAi has also uncovered a number of concerns that raise questions regarding the clinical application of this technology, including off-target effects, innate immune responses, and alterations in the endogenous microRNA (miRNA) pathway. However, over the past several years, work has been done to address these problems and a number of solutions are now being implemented to mitigate these potential risks. With a deeper understanding of RNAi and continued progress in designing RNAi effectors, viral vector-mediated RNAi has the potential to change the way many diseases are treated. PMID:20620113

Couto, Linda B; High, Katherine A

2010-10-01

4

Retrospective study of presumably allergic dogs examined over a one-year period at the Veterinary Faculty, University of Ljubljana, Slovenia  

Microsoft Academic Search

Two hundred and twelve animals examined over a one-year period at the Dermatology Department of Small Animal Clinic, Veterinary Faculty, University of Ljubljana, were included in a retrospective study. For further evaluation dogs with flea allergy dermatitis (FAD), Canine atopic disease (CAD) and Food hypersensitivity as the first differential diagnosis (n = 126) were considered. Among the clinical features in

Tina Kotnik

5

Long-Term Follow-up of Foamy Viral Vector-Mediated Gene Therapy for Canine Leukocyte Adhesion Deficiency  

PubMed Central

The development of leukemia following gammaretroviral vector-mediated gene therapy for X-linked severe combined immunodeficiency disease and chronic granulomatous disease (CGD) has emphasized the need for long-term follow-up in animals treated with hematopoietic stem cell gene therapy. In this study, we report the long-term follow-up (4–7 years) of four dogs with canine leukocyte adhesion deficiency (CLAD) treated with foamy viral (FV) vector-mediated gene therapy. All four CLAD dogs previously received nonmyeloablative conditioning with 200 cGy total body irradiation followed by infusion of autologous, CD34+ hematopoietic stem cells transduced by a FV vector expressing canine CD18 from an internal Murine Stem Cell Virus (MSCV) promoter. CD18+ leukocyte levels were >2% following infusion of vector-transduced cells leading to ongoing reversal of the CLAD phenotype for >4 years. There was no clinical development of lymphoid or myeloid leukemia in any of the four dogs and integration site analysis did not reveal insertional oncogenesis. These results showing disease correction/amelioration of disease in CLAD without significant adverse events provide support for the use of a FV vector to treat children with leukocyte adhesion deficiency type 1 (LAD-1) in a human gene therapy clinical trial. PMID:23531552

Bauer, Thomas R; Tuschong, Laura M; Calvo, Katherine R; Shive, Heather R; Burkholder, Tanya H; Karlsson, Eleanor K; West, Robert R; Russell, David W; Hickstein, Dennis D

2013-01-01

6

Jaagsiekte sheep retrovirus pseudotyped lentiviral vector-mediated gene transfer to fetal ovine lung  

Microsoft Academic Search

Viral vector-mediated gene transfer to the postnatal respiratory epithelium has, in general, been of low efficiency due to physical and immunological barriers, non-apical location of cellular receptors critical for viral uptake and limited transduction of resident stem\\/progenitor cells. These obstacles may be overcome using a prenatal strategy. In this study, HIV-1-based lentiviral vectors (LVs) pseudotyped with the envelope glycoproteins of

M G Davey; P W Zoltick; C A Todorow; M P Limberis; E D Ruchelli; H L Hedrick; A W Flake

2012-01-01

7

HSV vector-mediated modification of primary nociceptor afferents: an approach to inhibit chronic pain  

PubMed Central

Chronic pain is a serious medical condition with millions of sufferers for whom long-term therapies are either lacking or inadequate. Here we review the use of herpes simplex virus vectors as therapeutic tools to treat chronic pain by gene therapy. We describe an approach to inhibit chronic pain signaling whereby vector-mediated genes transferred to sensory nerves will modify the primary afferent nociceptor to prevent pain signaling to second-order nerves in the spinal cord. This approach may be used to reverse the chronic pain state of the nociceptor and could affect downstream pain-related changes in the central nervous system. PMID:19357694

Goss, JR; Gold, MS; Glorioso, JC

2009-01-01

8

Therapeutic effects of viral vector-mediated antiangiogenic gene transfer in malignant ascites.  

PubMed

Malignant ascites is a common complication of advanced intraabdominal neoplasms for which standard treatments are suboptimal. Evidence suggests that tumor-mediated angiogenesis and enhanced vascular permeability in the peritoneal wall due to high levels of vascular endothelial growth factor play a fundamental role in the pathogenesis of malignant ascites. To explore the advantage of viral vector-mediated "targeted antiangiogenic therapy" in ascites formation, we constructed and administered adenoviral vectors encoding several different antiangiogenic proteins (angiostatin, endostatin, platelet factor 4, and a fusion protein between angiostatin and endostatin) alone or in combination intraperitoneally in mice with peritoneal carcinomatosis from breast cancer (TA3 cells) and ovarian cancer (SKOV-3 i.p. and ES-2 cell lines) to explore the potential of additive or synergistic activity. Our data demonstrated statistically significant downregulation of ascites formation, tumor growth, vascularity, and prolongation of animal survival after intraperitoneal treatment with antiangiogenic adenoviral vectors in three different ascites tumor models. Combined treatment proved to be more effective than treatment with one vector alone. Reduced ascites formation was accompanied by decreased microvascular density in the peritoneal wall and increased apoptosis of tumor cells after administration of antiangiogenic vectors in vivo. Of interest was the observation that AdPF4 caused a significant decrease in the level of VEGF secreted by tumor cells both in vitro and in TA3 ascites tumor-bearing animals in vivo. These data suggest that adenoviral vector-mediated delivery of genes encoding antiangiogenic proteins may represent a potentially new treatment modality for malignant ascites. PMID:11560766

Hampl, M; Tanaka, T; Albert, P S; Lee, J; Ferrari, N; Fine, H A

2001-09-20

9

Assessment of CAR or CD46Dependent Adenoviral Vector-Mediated TRAIL Gene Therapy in Clinical Adenocarcinoma Lung Cancer Cells  

Microsoft Academic Search

Adenoviral vector-mediated transfer of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can be a powerful approach to lung cancer therapy. However, the efficiency of adenoviral vector gene transfer and the sensitivity to TRAIL-induced apoptosis in the context of adenoviral vector gene transfer have yet to be characterized in primary lung cancers. In this study, we investigated the expression of adenoviral receptor

Yong Wang; Lingdi Ma; Shizhong Wang; Yongyi Bao; Cheng Ni; Naifu Guan; Jianzhong Zhao; Xiaolong Fan

2009-01-01

10

Recombinant Adeno-Associated Virus Vector-Mediated Delivery of Antisense Interleukin5 Gene Attenuates Airway Remodeling in Allergic Rats  

Microsoft Academic Search

Background: Increasing evidence indicates that eosinophils contribute greatly to airway remodeling in asthma. Since interleukin-5 (IL-5) plays a critical role in the regulation of eosinophils in asthma, anti-IL-5 therapy may be a novel approach to inhibit airway remodeling in asthma. Objectives: In this study, we applied a recombinant adeno-associated virus vector-mediated antisense IL-5 gene delivery (rAAV-ASIL-5) system to investigate its

Daxiong Zeng; Yong Cao; Qingfeng Song; Chao Cao; Min Xie; Xiansheng Liu; Shengdao Xiong; Yongjian Xu; Weining Xiong

2011-01-01

11

AAV vector-mediated RNAi of Mutant Huntingtin Expression is Neuroprotective in a Novel Genetic Rat Model of Huntington's Disease  

PubMed Central

We report the characterization of a new rapid-onset model of Huntington’s disease (HD) generated by adeno-associated virus (AAV) vector-mediated gene transfer of N-terminal huntingtin constructs into the rat striatum. Expression of exon 1 of mutant huntingtin containing 70 CAG repeats rapidly led to neuropathological features associated with HD. In addition, we report novel data relating to neuronal transduction of AAV vectors that modulated the phenotype observed in this model. Quantitative RT-PCR revealed AAV vector-mediated expression in the striatum to over 100-fold the endogenous huntingtin level. Moreover, AAV vectors exhibited non-uniform transduction patterns in striatal neuronal populations and also axonal transport that led to transduction and neuronal cell death in the globus pallidus and substantia nigra. These findings may inform future studies utilizing AAV vectors for neurodegenerative disease modeling. Furthermore, RNA interference (RNAi) of mutant huntingtin expression mediated by virus vector delivery of short hairpin RNAs (shRNAs) ameliorates early-stage disease phenotypes in transgenic mouse models of HD, however whether shRNA-mediated knockdown of mutant huntingtin expression is neuroprotective has not been reported. AAV-shRNA mediated dramatic knockdown of HD70 expression, preventing striatal neurodegeneration and concomitant motor behavioral impairment. These results provide further support for AAV vector-mediated RNAi as a therapeutic strategy for HD. PMID:18388917

Franich, Nicholas R.; Fitzsimons, Helen L.; Fong, Dahna M.; Klugmann, Matthias; During, Matthew J.; Young, Deborah

2013-01-01

12

Jaagsiekte sheep retrovirus pseudotyped lentiviral vector-mediated gene transfer to fetal ovine lung.  

PubMed

Viral vector-mediated gene transfer to the postnatal respiratory epithelium has, in general, been of low efficiency due to physical and immunological barriers, non-apical location of cellular receptors critical for viral uptake and limited transduction of resident stem/progenitor cells. These obstacles may be overcome using a prenatal strategy. In this study, HIV-1-based lentiviral vectors (LVs) pseudotyped with the envelope glycoproteins of Jaagsiekte sheep retrovirus (JSRV-LV), baculovirus GP64 (GP64-LV), Ebola Zaire-LV or vesicular stomatitis virus (VSVg-LV) and the adeno-associated virus-2/6.2 (AAV2/6.2) were compared for in utero transfer of a green fluorescent protein (GFP) reporter gene to ovine lung epithelium between days 65 and 78 of gestation. GFP expression was examined on day 85 or 136 of gestation (term is ?145 days). The percentage of the respiratory epithelial cells expressing GFP in fetal sheep that received the JSRV-LV (3.18 × 10(8)-6.85 × 10(9) viral particles per fetus) was 24.6±0.9% at 3 weeks postinjection (day 85) and 29.9±4.8% at 10 weeks postinjection (day 136). Expression was limited to the surface epithelium lining fetal airways <100??m internal diameter. Fetal airways were amenable to VSVg-LV transduction, although the percentage of epithelial expression was low (6.6±0.6%) at 1 week postinjection. GP64-LV, Ebola Zaire-LV and AAV2/6.2 failed to transduce the fetal ovine lung under these conditions. These data demonstrate that prenatal lung gene transfer with LV engineered to target apical surface receptors can provide sustained and high levels of transgene expression and support the therapeutic potential of prenatal gene transfer for the treatment of congenital lung diseases. PMID:21654824

Davey, M G; Zoltick, P W; Todorow, C A; Limberis, M P; Ruchelli, E D; Hedrick, H L; Flake, A W

2012-02-01

13

Lymphocyte transformation in presumed ocular histoplasmosis  

SciTech Connect

Lymphocytes from individuals with inactive macular disciform lesions of presumed ocular histoplasmosis challenged with three histoplasmin antigens incorporated tritiated thymidine at a significantly higher rate than histoplasmin-stimulated lymphocytes of matched control and peripheral scar groups. This finding is consistent with the etiologic association of the disciform ocular syndrome and previous systemic infection with Histoplasma capsulatum. The disciform group had a higher mean response than the other two groups to pokeweed mitogen but not to phytohemagglutinin and had higher mean counts per minute to the specific antigens Toxoplasma gondii, Blastomyces dermatitidis, Cryptococcus neoformans, Mycobacterium tuberculosis, M battery, and M gaus, but not to Candida albicans. These data would suggest that individuals with the disciform lesion of presumed ocular histoplasmosis have a hyperreactive cellular immune response; this response may play an important role in the development of the disciform.

Ganley, J.P.; Nemo, G.J.; Comstock, G.W.; Brody, J.A.

1981-08-01

14

Presumed bilateral occipital neurosarcoidosis. A case report.  

PubMed

A 37-year-old man with a history of sarcoidosis, hypertension, asthma, depression and prior intravenous drug use presented with complaints of difficulty in finding his way around the house, headache, and blurred vision in both eyes. The symptoms had been increasing in severity over the prior several months. Physical examination showed normal visual acuity, pupil reactions, and fundi but severe, circumferential constriction of the visual fields bilaterally. The visual fields enlarged appropriately on increasing the distance from the patient to the tangent screen. Neuroimaging revealed bilateral, occipital meningeal involvement and parenchymal lesions consistent with sarcoidosis. Treatment with oral corticosteroids produced a mild subjective improvement in the patient's symptoms and stabilized the visual fields, without improving them. This case represents an unusual presentation of presumed neurosarcoidosis involving the visual pathways at the level of the occipital lobes. PMID:9532537

Givre, S J; Mindel, J S

1998-03-01

15

An AAV Vector-Mediated Gene Delivery Approach Facilitates Reconstitution of Functional Human CD8+ T Cells in Mice  

PubMed Central

In the present study, a novel adeno-associated virus (AAV) vector-mediated gene delivery approach was taken to improve the reconstitution of functional CD8+ T cells in humanized mice, thereby mimicking the human immune system (HIS). Human genes encoding HLA-A2 and selected human cytokines (A2/hucytokines) were introduced to an immune-deficient mouse model [NOD/SCID/IL2r?null (NSG) mice] using AAV serotype 9 (AAV9) vectors, followed by transplantation of human hematopoietic stem cells. NSG mice transduced with AAV9 encoding A2/hucytokines resulted in higher levels of reconstitution of human CD45+ cells compared to NSG mice transduced with AAV9 encoding HLA-A2 alone or HLA-A2-transgenic NSG mice. Furthermore, this group of HIS mice also mounted the highest level of antigen-specific A2-restricted human CD8+ T-cell response upon vaccination with recombinant adenoviruses expressing human malaria and HIV antigens. Finally, the human CD8+ T-cell response induced in human malaria vaccine-immunized HIS mice was shown to be functional by displaying cytotoxic activity against hepatocytes that express the human malaria antigen in the context of A2 molecules. Taken together, our data show that AAV vector-mediated gene delivery is a simple and efficient method to transfer multiple human genes to immune-deficient mice, thus facilitating successful reconstitution of HIS in mice. The HIS mice generated in this study should ultimately allow us to swiftly evaluate the T-cell immunogenicity of various human vaccine candidates in a pre-clinical setting. PMID:24516613

Wilson, James M.; Tsuji, Moriya

2014-01-01

16

[Surgical treatments of presumed benign ovarian tumors].  

PubMed

The surgical management of presumed benign ovarian tumors (PBOT) must ensure complete removal of the cyst, reduce the risk of recurrence (especially in case of endometrioma), prevent any risk of tumor dissemination, and must preserve healthy ovarian tissue. Asymptomatic PBOT should not be punctured. Expectation is preferable to puncture. Laparoscopy is the gold standard for surgical treatment. Single-port laparoscopy is feasible and being evaluated. Peritoneal exploration and peritoneal cytology are conventionally performed. Ovarian cystectomy, oophorectomy and salpingo-oophorectomy are the standard techniques. Suture after cystectomy is not recommended. The extraction of the cyst using an endoscopic bag is recommended. Peritoneal washing after surgery is recommended. The use of anti-adhesions barriers is not recommended routinely. In case of dermoid cyst, cystectomy by mesial incision may decrease the risk of intraoperative rupture. In case of endometrioma, the intraperitoneal cystectomy is recommended as first-line surgery. Exclusive bipolar coagulation should be avoided because of increased risk of recurrence and lower pregnancy rates. There is no argument to support the use of plasma energy and CO2 laser in the treatment of endometriomas. Ethanol sclerotherapy may be proposed in patients with recurrent endometriomas after surgery and referred to medically assisted procreation, although there is no comparative trial with cystectomy. PMID:24210231

Borghese, B; Marzouk, P; Santulli, P; de Ziegler, D; Chapron, C

2013-12-01

17

20 CFR 219.24 - Evidence of presumed death.  

Code of Federal Regulations, 2013 CFR

... 2012-04-01 true Evidence of presumed death. 219.24 Section 219.24 Employees...EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of presumed death. When a person cannot be proven dead but...

2013-04-01

18

20 CFR 219.24 - Evidence of presumed death.  

Code of Federal Regulations, 2012 CFR

...2012-04-01 false Evidence of presumed death. 219.24 Section 219.24 Employees...EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of presumed death. When a person cannot be proven dead but...

2012-04-01

19

20 CFR 219.24 - Evidence of presumed death.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 false Evidence of presumed death. 219.24 Section 219.24 Employees...EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of presumed death. When a person cannot be proven dead but...

2011-04-01

20

20 CFR 219.24 - Evidence of presumed death.  

... 2012-04-01 true Evidence of presumed death. 219.24 Section 219.24 Employees...EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of presumed death. When a person cannot be proven dead but...

2014-04-01

21

Colorblind Dogs  

NSDL National Science Digital Library

This activity (on page 2 of the PDF) is a full inquiry investigation into dogs' ability (or inability) to see color. Learners conduct an experiment by first performing a control test and then experimenting to see if dogs are able to fetch colored balls amid a background of gray balls. Learners collect, record, and graph the data to draw conclusions about colorblindness in dogs. Relates to linked video, DragonflyTV: Colorblind Dogs.

Twin Cities Public Television, Inc.

2005-01-01

22

Dogs and Preventing Dog Bites  

MedlinePLUS

... how do you prevent one? Use Your Dog Manners Do you know what to do if a ... you? When we say to use your "dog manners," we don't mean you should eat off ... you can also have some equally good dog manners. That means taking certain steps every time you ...

23

20 CFR 219.24 - Evidence of presumed death.  

Code of Federal Regulations, 2010 CFR

...1 2010-04-01 2010-04-01 false Evidence of presumed death. 219.24 Section 219...REGULATIONS UNDER THE RAILROAD RETIREMENT ACT EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of...

2010-04-01

24

10 CFR 436.13 - Presuming cost-effectiveness results.  

...If the investment and other costs for an energy or water conservation measure considered for retrofit to an existing...agency may presume that an investment in an energy or water conservation measure retrofit to an existing Federal...

2014-01-01

25

10 CFR 436.13 - Presuming cost-effectiveness results.  

Code of Federal Regulations, 2013 CFR

...If the investment and other costs for an energy or water conservation measure considered for retrofit to an existing...agency may presume that an investment in an energy or water conservation measure retrofit to an existing Federal...

2013-01-01

26

10 CFR 436.13 - Presuming cost-effectiveness results.  

Code of Federal Regulations, 2012 CFR

...If the investment and other costs for an energy or water conservation measure considered for retrofit to an existing...agency may presume that an investment in an energy or water conservation measure retrofit to an existing Federal...

2012-01-01

27

10 CFR 436.13 - Presuming cost-effectiveness results.  

Code of Federal Regulations, 2010 CFR

...If the investment and other costs for an energy or water conservation measure considered for retrofit to an existing...agency may presume that an investment in an energy or water conservation measure retrofit to an existing Federal...

2010-01-01

28

10 CFR 436.13 - Presuming cost-effectiveness results.  

Code of Federal Regulations, 2011 CFR

...If the investment and other costs for an energy or water conservation measure considered for retrofit to an existing...agency may presume that an investment in an energy or water conservation measure retrofit to an existing Federal...

2011-01-01

29

Functional metastatic parathyroid adenocarcinoma in a dog  

PubMed Central

A 12-year-old dachshund dog was presented for persistent hypercalcemia and hyperparathyroidism despite bilateral parathyroidectomy. Magnetic resonance imaging of the head, neck, and cranial mediastinum identified an increased number of cranial mediastinal lymph nodes with heterogeneous signal intensity. Hypercalcemia and hyperparathyroidism resolved after surgery to remove multiple cranial mediastinal lymph nodes, one of which contained presumed metastatic parathyroid tissue. PMID:24688141

Kishi, Erin N.; Holmes, Shannon P.; Abbott, Jeffrey R.; Bacon, Nicholas J.

2014-01-01

30

Prairie Dogs  

Microsoft Academic Search

Prairie dogs are stocky burrowing rodents that live in colonies called “towns.” French explorers called them “little dogs” because of the barking noise they make. Their legs are short and muscular, adapted for digging. The tail and other extremities are short. Their hair is rather coarse with little underfur, and is sandy brown to cinnamon in color with grizzled black

Scott E. Hygnstrom; Dallas R. Virchow

1994-01-01

31

The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery.  

PubMed

Retroviral vector-mediated gene transfer has been central to the development of gene therapy. Retroviruses have several distinct advantages over other vectors, especially when permanent gene transfer is the preferred outcome. The most important advantage that retroviral vectors offer is their ability to transform their single stranded RNA genome into a double stranded DNA molecule that stably integrates into the target cell genome. This means that retroviral vectors can be used to permanently modify the host cell nuclear genome. Recently, retroviral vector-mediated gene transfer, as well as the broader gene therapy field, has been re-invigorated with the development of a new class of retroviral vectors which are derived from lentiviruses. These have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a quantum leap in technology and seemingly offer the means to achieve significant levels of gene transfer in vivo.The ability of retroviruses to integrate into the host cell chromosome also raises the possibility of insertional mutagenesis and oncogene activation. Both these phenomena are well known in the interactions of certain types of wild-type retroviruses with their hosts. However, until recently they had not been observed in replication defective retroviral vector-mediated gene transfer, either in animal models or in clinical trials. This has meant the potential disadvantages of retroviral mediated gene therapy have, until recently, been seen as largely, if not entirely, hypothetical. The recent clinical trial of gammac mediated gene therapy for X-linked severe combined immunodeficiency (X-SCID) has proven the potential of retroviral mediated gene transfer for the treatment of inherited metabolic disease. However, it has also illustrated the potential dangers involved, with 2 out of 10 patients developing T cell leukemia as a consequence of the treatment. A considered review of retroviral induced pathogenesis suggests these events were qualitatively, if not quantitatively, predictable. In addition, it is clear that the probability of such events can be greatly reduced by relatively simple vector modifications, such as the use of self-inactivating vectors and vectors derived from non-oncogenic retroviruses. However, these approaches remain to be fully developed and validated. This review also suggests that, in all likelihood, there are no other major retroviral pathogenetic mechanisms that are of general relevance to replication defective retroviral vectors. These are important conclusions as they suggest that, by careful design and engineering of retroviral vectors, we can continue to use this gene transfer technology with confidence. PMID:15310406

Anson, Donald S

2004-08-13

32

The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery  

PubMed Central

Retroviral vector-mediated gene transfer has been central to the development of gene therapy. Retroviruses have several distinct advantages over other vectors, especially when permanent gene transfer is the preferred outcome. The most important advantage that retroviral vectors offer is their ability to transform their single stranded RNA genome into a double stranded DNA molecule that stably integrates into the target cell genome. This means that retroviral vectors can be used to permanently modify the host cell nuclear genome. Recently, retroviral vector-mediated gene transfer, as well as the broader gene therapy field, has been re-invigorated with the development of a new class of retroviral vectors which are derived from lentiviruses. These have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a quantum leap in technology and seemingly offer the means to achieve significant levels of gene transfer in vivo. The ability of retroviruses to integrate into the host cell chromosome also raises the possibility of insertional mutagenesis and oncogene activation. Both these phenomena are well known in the interactions of certain types of wild-type retroviruses with their hosts. However, until recently they had not been observed in replication defective retroviral vector-mediated gene transfer, either in animal models or in clinical trials. This has meant the potential disadvantages of retroviral mediated gene therapy have, until recently, been seen as largely, if not entirely, hypothetical. The recent clinical trial of ?c mediated gene therapy for X-linked severe combined immunodeficiency (X-SCID) has proven the potential of retroviral mediated gene transfer for the treatment of inherited metabolic disease. However, it has also illustrated the potential dangers involved, with 2 out of 10 patients developing T cell leukemia as a consequence of the treatment. A considered review of retroviral induced pathogenesis suggests these events were qualitatively, if not quantitatively, predictable. In addition, it is clear that the probability of such events can be greatly reduced by relatively simple vector modifications, such as the use of self-inactivating vectors and vectors derived from non-oncogenic retroviruses. However, these approaches remain to be fully developed and validated. This review also suggests that, in all likelihood, there are no other major retroviral pathogenetic mechanisms that are of general relevance to replication defective retroviral vectors. These are important conclusions as they suggest that, by careful design and engineering of retroviral vectors, we can continue to use this gene transfer technology with confidence. PMID:15310406

Anson, Donald S

2004-01-01

33

Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson's disease  

PubMed Central

Viral vector-mediated gene transfer utilizing adeno-associated viral vectors has recently entered clinical testing as a novel tool for delivery of therapeutic agents to the brain. Clinical trials in Parkinson’s disease using adeno-associated viral vector-based gene therapy have shown the safety of the approach. Further efforts in this area will show if gene-based approaches can rival the therapeutic efficacy achieved with the best pharmacological therapy or other, already established, surgical interventions. One of the strategies under development for clinical application is continuous 3,4-dihydroxyphenylalanine delivery. This approach has been shown to be efficient in restoring motor function and reducing established dyskinesias in rats with a partial lesion of the nigrostriatal dopamine projection. Here we utilized high purity recombinant adeno-associated viral vectors serotype 5 coding for tyrosine hydroxylase and its co-factor synthesizing enzyme guanosine-5'-triphosphate cyclohydrolase-1, delivered at an optimal ratio of 5 : 1, to show that the enhanced 3,4-dihydroxyphenylalanine production obtained with this optimized delivery system results in robust recovery of function in spontaneous motor tests after complete dopamine denervation. We found that the therapeutic efficacy was substantial and could be maintained for at least 6 months. The tyrosine hydroxylase plus guanosine-5'-triphosphate cyclohydrolase-1 treated animals were resistant to developing dyskinesias upon peripheral l-3,4-dihydroxyphenylalanine drug challenge, which is consistent with the interpretation that continuous dopamine stimulation resulted in a normalization of the post-synaptic response. Interestingly, recovery of forelimb use in the stepping test observed here was maintained even after a second lesion depleting the serotonin input to the forebrain, suggesting that the therapeutic efficacy was not solely dependent on dopamine synthesis and release from striatal serotonergic terminals. Taken together these results show that vector-mediated continuous 3,4-dihydroxyphenylalanine delivery has the potential to provide significant symptomatic relief even in advanced stages of Parkinson’s disease. PMID:20129936

Carlsson, Thomas; Cederfjall, Erik Ahlm; Carta, Manolo; Kirik, Deniz

2010-01-01

34

Dog Whisperer  

E-print Network

Broadcast Transcript: As we mentioned in an earlier Postcard, dogs have only recently become favored pets rather than favorite meals here in China. And, if you needed further proof of this transformation, here it is: Cesar Millan has been tapped...

Hacker, Randi

2013-05-22

35

Dog Bite Prevention  

MedlinePLUS

... records. Consult with your veterinarian about your dog’s aggressive action. Your veterinarian can examine your dog to ... or one they know. Some owners actually promote aggression in their dogs or allow aggression to go ...

36

Presumed consent for transplantation: a dead issue after Alder Hey?  

PubMed Central

In the wake of scandals about the unauthorised retention of organs following postmortem examination, the issue of valid consent (or the lack of it) has returned to the forefront. Emphasis is put on obtaining explicit authorisation from the patient or family prior to any medical intervention, including those involving the dead. Although the controversies in the UK arose from the retention of human material for education or research rather than therapy, concern has been expressed that public mistrust could also adversely affect organ donation for transplantation. At the same time, however, the British Medical Association (BMA) continues to call for a shift to a system of presumed consent for organ transplantation. This apparent inconsistency can be justified because valid distinctions exist between the reasons requiring explicit consent for retention and the acceptability of presumed consent for transplantation. This paper argues for introducing a system of presumed consent for organ donation, given the overwhelming expressions of public support for transplantation. Ongoing legislative review in the UK provides an ideal chance to alter the default position to one where potential donors can simply acquiesce or opt out of donation. Combined with consultation with their relatives, this could be a much better method of realising individuals' wishes. It would also achieve a better balance between the duties owed to the deceased and those owed to people awaiting a transplant. PMID:12796433

English, V; Sommerville, A

2003-01-01

37

Presumed ocular histoplasmosis syndrome and linear streak lesions.  

PubMed Central

Five cases of subretinal neovascular membranes in the macula associated with punched out chorioretinal scars and linear streaks were seen in five Dutch patients. Clinically the fundus lesions are consistent with those of presumed ocular histoplasmosis syndrome (POHS) seen in the United States of America. Cutaneous serological testing for histoplasmin reactivity was negative in the three patients tested. Of special interest is the presence of linear streaks in association with POHS. They have not been previously described in patients from Europe with this syndrome. Images PMID:2757993

Bottoni, F G; Deutman, A F; Aandekerk, A L

1989-01-01

38

Dramatic regression of presumed acquired retinal astrocytoma with photodynamic therapy.  

PubMed

Photodynamic therapy (PDT) has been used for treatment of various intraocular tumors including choroidal hemangioma, vasoproliferative tumor, amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma. This case report documents the effect of PDT for a presumed acquired retinal astrocytoma. A 42-year-old female with a juxtapapillary acquired astrocytoma was treated with a single session of PDT using standard parameters. The tumor showed dramatic regression over 6 months into a fibrotic scar. It remained regressed and stable with 20/20 vision after 51 months of follow-up. We believe that PDT can be used as a primary treatment for acquired retinal astrocytoma. PMID:25100919

Tuncer, Samuray; Cebeci, Zafer

2014-01-01

39

Dramatic Regression of Presumed Acquired Retinal Astrocytoma with Photodynamic Therapy  

PubMed Central

Photodynamic therapy (PDT) has been used for treatment of various intraocular tumors including choroidal hemangioma, vasoproliferative tumor, amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma. This case report documents the effect of PDT for a presumed acquired retinal astrocytoma. A 42-year-old female with a juxtapapillary acquired astrocytoma was treated with a single session of PDT using standard parameters. The tumor showed dramatic regression over 6 months into a fibrotic scar. It remained regressed and stable with 20/20 vision after 51 months of follow-up. We believe that PDT can be used as a primary treatment for acquired retinal astrocytoma. PMID:25100919

Tuncer, Samuray; Cebeci, Zafer

2014-01-01

40

Renal clearance studies of effect of left atrial distension in the dog.  

NASA Technical Reports Server (NTRS)

Investigation of the water diuresis of left atrial distension in 16 dogs on the basis of clearance studies employing hydration, chronic and acute salt loading, deoxycorticosterone (DOCA) in excess, and distal tubular nephron blockade with diuretics. The diuresis was found in hydrated and salt-loaded dogs and was independent of DOCA and presumed renin depletion. It was not found in five dogs after distal tubular blockade. No significant reproducible saluresis was ever documented. The water diuresis was always stopped by exogenous vasopressin (seven dogs). Antidiuretic hormone inhibition with distal tubular nephron water permeability changes appears to be the sole mechanism of the diuresis of left atrial distension in the dog.

Kinney, M. J.; Discala, V. A.

1972-01-01

41

Adenovirus vector-mediated herpes simplex virus-thymidine kinase gene/ganciclovir system exhibits anti-tumor effects in an orthotopic hepatocellular carcinoma model.  

PubMed

Adenovirus vector-mediated herpes simplex virus-thymidine kinase/ganciclovir (ADV.tk/GCV) system is a promising approach for cancer gene therapy. This study aimed to investigate the anti-tumor efficacy and the underlying mechanisms of ADV.tk/GCV system in orthotopic hepatocellular carcinoma (HCC) model. A total of 132 female nude mice orthotopic HCC models were established and tumors were directly injected with ADV.tk (5.0 x 10(6) vector particles/kg) or saline solution, 24 h later the animals were intraperitoneally administrated by ganciclovir (30 mg/kg) or saline solution for 7 consecutive days. We observed that ADV.tk/GCV resulted in a significant regression of tumor growth and a significant prolongation of survival of the mice. At each given time point, the percentages of cleaved caspae-3, caspase-9 and TUNEL positive cells were significantly higher in the ADV.tk + GCV group than saline group (P < 0.005), while CD31 and VEGF staining were significantly less in ADV.tk + GCV group than in saline group (P < 0.005). In summary, ADV.tk/GCV system exhibits dramatic anti-tumor effects in orthotopic hepatocellular carcinoma model by promoting apoptosis and inhibiting angiogenesis, and is a promising treatment strategy for hepatic carcinoma. PMID:25073402

Zhu, Ruidong; Chen, Dexi; Lin, Dongdong; Lu, Fudong; Yin, Jiming; Li, Ning

2014-07-01

42

Cooperative effects of adenoviral vector-mediated interleukin 12 gene therapy with radiotherapy in a preclinical model of metastatic prostate cancer.  

PubMed

We investigated the potential benefits of combining adenoviral vector mediated in situ interleukin-12 (AdmIL-12) gene therapy with radiation therapy (XRT) to enhance therapeutic efficacy. In a metastatic mouse prostate cancer cell line, 178-2 BMA, AdmIL-12+XRT demonstrated enhanced therapeutic activities in vitro as determined by clonogenic survival, apoptosis, and mIL-12 levels. At the molecular level, increased expression of tumor necrosis factor-alpha mRNA was specific for the combined therapy. In a subcutaneous 178-2 BMA in vivo model, the combination of AdmIL-12+XRT produced statistically significant tumor growth suppression compared to control vector Adbetagal, Adbetagal XRT, or AdmIL-12 as monotherapy. In addition, significant prolongation of survival was demonstrated for the combination of AdmIL-12+XRT. The combination of AdmIL-12+XRT significantly suppressed both spontaneous and pre-established lung metastases, and led to a prolonged elevation of serum IL-12 and significantly increased natural killer (NK) activities. Importantly, in vivo depletion of NK cells resulted in significant attenuation of the antimetastatic activities of AdmIL-12 alone or AdmIL-12+XRT. These combined effects suggest that AdIL-12 gene therapy together with radiotherapy may achieve maximal tumor control (both local and systemic) in selected prostate cancer patients via radio-gene therapy induced local cytotoxicity and local and systemic antitumor immunity. PMID:17024109

Fujita, T; Timme, T L; Tabata, K; Naruishi, K; Kusaka, N; Watanabe, M; Abdelfattah, E; Zhu, J X; Ren, C; Ren, C; Yang, G; Goltsov, A; Wang, H; Vlachaki, M T; Teh, B S; Butler, E B; Thompson, T C

2007-02-01

43

Cloning Dogs  

E-print Network

Broadcast Transcript: For those of you who have put off cloning your favorite pet due to the exorbitant cost, good news! The process just got cheaper. A biotech company here in South Korea has discovered that stems cells from the fat tissue in a dog...

Hacker, Randi

2009-03-08

44

Dog Fights  

ERIC Educational Resources Information Center

Bringing service animals into schools raises serious questions about how to meet one student's special needs while ensuring the educational well-being of all. This article discusses how schools grapple with the practical and legal questions involved in allowing service dogs on campus. The author cites a case in 2009 called "Kalbfleisch v. Columbia…

Taylor, Kelley R.

2010-01-01

45

Dog Breeding  

NSDL National Science Digital Library

This online Flash game gets learners thinking like geneticists in order to breed a border collie puppy with select traits, including coat color, coat length, and ear length. Progressive levels of play encourage learners as they move from novice to master breeders. Learners can click on the Why button to learn more about genes and dog breeding.

Twin Cities Public Television, Inc.

2006-01-01

46

Dog Breeds  

NSDL National Science Digital Library

Recently, designer mutts like the Labradoodle -- a cross between a Labarador retriever and a poodle -- have become popular. A listener wanted to know if some kinds of dogs are just too different to make puppies. This Science Update explores the cross breeding of species.

;

2004-07-05

47

Ask Dog Lady  

NSDL National Science Digital Library

What to do with a problem dog? What is the best book on dog training? Would Tony Soprano benefit from owning a dog? How can you trust your dog walker with your dog? All these questions are addressed by the Dog Lady, who gives advice, as she says herself, on "dogs, love, and life." Always readable and often funny, the Dog Lady answers emails from viewers with questions about their canine pets. Users can read recent columns or review the "Best in Show" archive, a collection of the Dog Lady's most memorable advice. [CH

2003-01-01

48

Presumed Symbolic Use of Diurnal Raptors by Neanderthals  

PubMed Central

In Africa and western Eurasia, occurrences of burials and utilized ocher fragments during the late Middle and early Late Pleistocene are often considered evidence for the emergence of symbolically-mediated behavior. Perhaps less controversial for the study of human cognitive evolution are finds of marine shell beads and complex designs on organic and mineral artifacts in early modern human (EMH) assemblages conservatively dated to ?100–60 kilo-years (ka) ago. Here we show that, in France, Neanderthals used skeletal parts of large diurnal raptors presumably for symbolic purposes at Combe-Grenal in a layer dated to marine isotope stage (MIS) 5b (?90 ka) and at Les Fieux in stratigraphic units dated to the early/middle phase of MIS 3 (60–40 ka). The presence of similar objects in other Middle Paleolithic contexts in France and Italy suggest that raptors were used as means of symbolic expression by Neanderthals in these regions. PMID:22403717

Morin, Eugčne; Laroulandie, Véronique

2012-01-01

49

National Detector Dog Manual.  

National Technical Information Service (NTIS)

The National Detector Dog Manual covers background information, procedures, health care, and training related to detector dog activities. The procedures have a national focus to guide detector dog activities, and they are supplemental to general operation...

2004-01-01

50

Dog Bite Emergencies  

MedlinePLUS

... Emergency Care Animal Welfare Veterinary Careers Public Health Dog bite emergencies What do I do if I’ ... vaccination records. What do I do if my dog bites someone? Dog bites are scary for everyone ...

51

Adenovirus vector-mediated ex vivo gene transfer of brain-derived neurotrophic factor to bone marrow stromal cells promotes axonal regeneration after transplantation in completely transected adult rat spinal cord  

Microsoft Academic Search

The aim of this study was to evaluate the efficacy in adult rat completely transected spinal cord of adenovirus vector-mediated\\u000a brain-derived neurotrophic factor (BDNF) ex vivo gene transfer to bone marrow stromal cells (BMSC). BMSC were infected with\\u000a adenovirus vectors carrying ?-galactosidase (AxCALacZ) or BDNF (AxCABDNF) genes. The T8 segment of spinal cord was removed\\u000a and replaced by graft containing

Masao Koda; Takahito Kamada; Masayuki Hashimoto; Masazumi Murakami; Hiroshi Shirasawa; Seiichiro Sakao; Hidetoshi Ino; Katsunori Yoshinaga; Shuhei Koshizuka; Hideshige Moriya; Masashi Yamazaki

2007-01-01

52

PBS-Nova: Dogs And More Dogs  

NSDL National Science Digital Library

This Nova website, designed to accompany a television Feature Program on the world of Dogs, asks "How and why did man's best friend evolve from wolves, and why are dogs so remarkably diverse today?" The site showcases a slide show on working dogs and an interactive matching game entitled, Dogs Around the World. Also included at this website are a Teacher's Guide, a Links and Books page, and an Inquiry Article about Dog diversity. Additionally, this site links to the TV program transcript and to a recent "washingtonpost.com discussion with biologist and dog expert Ray Coppinger."

53

Presumed consent: the solution to the critical organ donor shortage?  

PubMed

Extraordinary advances in science and medicine such as transplantation of human tissues not only bring about previously unimaginable societal benefits but also create profound implications that involve autonomy and belonging, opposing moral considerations, and legal concerns. Today, technology is changing faster than our values. The issue of salvaging organs from the dead to meet the escalating need for human organs for lifesaving organ transplantation has evolved into an intricate web of interdisciplinary concerns and value conflicts; right and wrong are opinions and consensus does not seem to exist. This organ supply-demand mismatch, as well as suggestions for its resolution, has become a major challenge to the transplant community and to those in political and bioethical arenas. A methodical transition to presumed consent, or opting-out legislation, which removes the burden of decision from the family and the burden of request from the healthcare professional, may be the only solution to correct the imbalance between human organ need and availability. PMID:7489043

Futterman, L G

1995-09-01

54

Clinically diagnosed poliomyelitis in a presumably vaccinated population.  

PubMed

Vaccination against poliomyelitis has been compulsory all over Egypt since 1968. Therefore, it is presumed that all infants and children below six years have already been vaccinated. This study is planned to estimate the magnitude of paralytic poliomyelitis in Egypt after six years compulsory vaccination. The cases studied were investigated with regard to socioeconomic status and history and place of vaccination, association of vomiting and diarrhoea or breast feeding within two hours of vaccination, and blood grouping. These results were compared with those of a control group of non-paralytic cases chosen at random from patients who visited the same hospital. Samples of the vaccine were collected from different centres in which children received vaccination and were titrated to estimate their potency at Agouza Laboratories for Vaccines and Sera. The results revealed that still we have a high incidence of poliomyelitis viz : 985/100,000 out-patients, also males are more affected than females with sex ratio 3:2. Of the paralytic cases 22% had proper vaccination while improper vaccination was found in 78%. There was predominance of blood group O among the paralytic cases. The detailed results and discussion of paralytic cases compared to the control has been also fulfilled. Tiltration of the vaccine revealed a lower than the accepted standard indicating altered potency. PMID:1222895

El-Deeb, H; El-Rafie, M

1975-04-01

55

Two successive necrotic lesions secondary to presumed loxosceles envenomation.  

PubMed

Brown recluse spider (Loxosceles reclusa) envenomations with subsequent necrotic skin lesions occur infrequently, and systemic loxoscelism is rarer still. We report a case of 2 successive developing necrotic lesions, each on adjacent medial aspects of the legs, secondary to presumed Loxosceles envenomation. A 31-year-old man with no significant past medical history presented to the emergency department with 2, large, necrotic lesions, 1 on each medial thigh. They had progressed over the course of 1 month from small blisters to large necrotic lesions with eschar. He underwent surgical debridement without skin grafting with no further complications. Bites from recluse spiders that progress to necrosis usually present as single lesions. The differential diagnoses for a necrotic skin lesion is large. The presence of more than 1 lesion argues against Loxosceles envenomation; however, in the absence of underlying infection, systemic diseases, immunodeficiency, or malignancy, the diagnosis must be considered if the case presents in an endemic area. Brown recluse spiders rarely bite multiple times, thus confounding the diagnosis of an already nonspecific clinical finding. PMID:23352313

Tarullo, David B; Jacobsen, Ryan C; Algren, D Adam

2013-06-01

56

Gaze-following behind barriers in domestic dogs.  

PubMed

Although gaze-following abilities have been demonstrated in a wide range of species, so far no clear evidence has been available for dogs. In the current study, we examined whether dogs follow human gaze behind an opaque barrier in two different contexts, in a foraging situation and in a non-foraging situation (food involved vs. food not involved in the situation). We assumed that dogs will spontaneously follow the human gaze and that the foraging context will have a positive effect on dogs' gaze-following behaviour by causing an expectation in the dogs that food might be hidden somewhere in the room and might be communicated by the experimenter. This expectation presumably positively affects their motivational and attentional state. Here, we report that dogs show evidence of spontaneous gaze-following behind barriers in both situations. According to our findings, the dogs gazed earlier at the barrier in the indicated direction in both contexts. However, as we expected, the context also has some effect on dogs' gaze-following behaviour, as more dogs gazed behind the barrier in the indicated direction in the foraging situation. The present results also support the idea that gaze-following is a characteristic skill in mammals which may more easily emerge in certain functional contexts. PMID:24816625

Met, Amandine; Miklósi, Adám; Lakatos, Gabriella

2014-11-01

57

Familial immotile-cilia syndrome in English springer spaniel dogs.  

PubMed

A laboratory-maintained colony of English springer spaniel dogs heterozygous for a putative autosomal recessive immotile-cilia syndrome (ICS) has been studied. Matings between dogs thought to be heterozygous for ICS resulted in 22 pups, five (three males and two females) of which were homozygous for ICS. Four of the five ICS-affected dogs had chronic rhinitis and bronchopneumonia. The other dog had a serious nasal discharge and died at 10 days. Four dogs had situs inversus totalis (kartagener syndrome), and the two males of reproductive age were azoospermic. In the two ICS dogs studied for ciliary function, in vivo mucociliary clearance was absent, and in vitro ciliary beat was rarely observed and of low frequency. Scanning and transmission electron microscopy disclosed the same lesions in respiratory cilia from all dogs with ICS, including random orientation and partial outer dynein arm deficiency. Four of five dogs with ICS had dilated lateral ventricles. One female pup with neonatal rhinitis and bronchopneumonia, situs solitus, and dilated lateral ventricles was presumed to be homozygous for ICS, but died without functional or structural confirmation of defective respiratory cilia. An autosomal recessive mode of inheritance for the ciliary defects and respiratory signs of ICS in these dogs is proposed. PMID:2801763

Edwards, D F; Kennedy, J R; Patton, C S; Toal, R L; Daniel, G B; Lothrop, C D

1989-07-01

58

[Ovarian tumor markers of presumed benign ovarian tumors].  

PubMed

Cancer Antigen 125 (CA125) and Human Epididymis Protein 4 (HE4) are the most studied ovarian tumor markers. Their diagnostic performance for identification of ovarian cancer are superior to CA19-9, CA72-4, and carcinoembryonic antigen, which are no more recommended for the diagnosis of presumed benign ovarian tumor. HE4 (>140 pmol/L) is superior to CA125 (>30 U/mL) in terms of specificity and positive likelihood ratio. CA125 and HE4 can be combined into an algorithm ROMA, or associated to clinical information (composite index), biological data (OVA1) or imaging (Risk for Malignancy Index (RMI), LR2). ROMA algorithm is an exponential equation combining plasmatic concentrations of HE4 and CA125. ROMA is more sensitive and less specific than HE4 in predicting epithelial ovarian cancer. ROMA is more accurate in post-menopausal women. The performance of ROMA is lower than the ultrasound model LR2 in differentiating malignant from benign ovarian tumors, whatever the hormonal status. The composite index combining CA125 with a symptoms index (pain, abdominal distension, bloating, difficulty eating) has a good sensitivity in a screening program, but because of a 12% false positive rate, ultrasound is required before management. The RMI algorithm is based on serum CA125, ultrasound findings (septation, solid zones, metastases, ascite, bilaterality) and menopausal status. RMI is less sensitive, but more specific than ROMA or OVA1 for the classification of ovarian masses. The addition of HE4 to RMI seems to be the most accurate. The subjective evaluation of ovarian cysts by sonography and color Doppler is better than ROMA and RMI algorithms, and not affected by the hormonal status. PMID:24210243

Lahlou, N; Brun, J-L

2013-12-01

59

‘Status dogs’ and gangs  

Microsoft Academic Search

In the light of the recent rapid growth in the ownership of ‘status dogs’ in the UK, and drawing upon research conducted in Britain and North America, this article considers the motivation of the dogs' owners, the relationship between the ownership of ‘status dogs’ and urban street gangs, and the social impact of these dogs.

Simon Harding

2010-01-01

60

Pre-Columbian origins of Native American dog breeds, with only limited replacement by European dogs, confirmed by mtDNA analysis  

PubMed Central

Dogs were present in pre-Columbian America, presumably brought by early human migrants from Asia. Studies of free-ranging village/street dogs have indicated almost total replacement of these original dogs by European dogs, but the extent to which Arctic, North and South American breeds are descendants of the original population remains to be assessed. Using a comprehensive phylogeographic analysis, we traced the origin of the mitochondrial DNA lineages for Inuit, Eskimo and Greenland dogs, Alaskan Malamute, Chihuahua, xoloitzcuintli and perro sín pelo del Peru, by comparing to extensive samples of East Asian (n = 984) and European dogs (n = 639), and previously published pre-Columbian sequences. Evidence for a pre-Columbian origin was found for all these breeds, except Alaskan Malamute for which results were ambigous. No European influence was indicated for the Arctic breeds Inuit, Eskimo and Greenland dog, and North/South American breeds had at most 30% European female lineages, suggesting marginal replacement by European dogs. Genetic continuity through time was shown by the sharing of a unique haplotype between the Mexican breed Chihuahua and ancient Mexican samples. We also analysed free-ranging dogs, confirming limited pre-Columbian ancestry overall, but also identifying pockets of remaining populations with high proportion of indigenous ancestry, and we provide the first DNA-based evidence that the Carolina dog, a free-ranging population in the USA, may have an ancient Asian origin. PMID:23843389

van Asch, Barbara; Zhang, Ai-bing; Oskarsson, Mattias C. R.; Klütsch, Cornelya F. C.; Amorim, António; Savolainen, Peter

2013-01-01

61

Dog epilepsy gene  

NSDL National Science Digital Library

Scientists have now identified a genetic mutation responsible for epilepsy in dogs. Further research on dogs with this mutation might help researchers better understand how to treat or prevent seizures in humans with Lafora disease, according to the authors.

American Association for the Advancement of Science (AAAS;)

2005-01-07

62

Genetic evaluation of Addison's disease in the Portuguese Water Dog  

PubMed Central

Background Addison's disease, also known as hypoadrenocorticism, has been reported in many individual dogs, although some breeds exhibit a greater incidence than the population as a whole. Addison's is presumed to be an autoimmune mediated hereditary defect but the mode of inheritance remains unclear. In particular, the heritability and mode of inheritance have not been defined for the Portuguese Water Dog although Addison's is known to be prevalent in the breed. Results The analyses present clear evidence that establishes Addison's disease as an inherited disorder in the Portuguese Water Dog with an estimate of heritability of 0.49 (± 0.16); there were no differences in risk for disease across sexes (p > 0.49). Further, the complex segregation analysis provides suggestive evidence that Addison's disease in the Portuguese Water Dog is inherited under the control of a single, autosomal recessive locus. Conclusion The high heritability and mode of inheritance of Addison's disease in the Portuguese Water Dog should enable the detection of segregating markers in a genome-wide scan and the identification of a locus linked to Addison's. Though the confirmation of Addison's disease as an autosomal recessive disorder must wait until the gene is identified, breeders of these dogs may wish to keep the present findings in mind as they plan their breeding programs to select against producing affected dogs. PMID:16670022

Oberbauer, AM; Bell, JS; Belanger, JM; Famula, TR

2006-01-01

63

Sight in Dogs  

Microsoft Academic Search

I THINK Mr. Kingsley rather underrates the exercise of the organs of vision by the dog when, in comparing it with the horse, he writes,-`` The dog, who has smelt everything, but looked at very little.'' Now it is true that the dog does not look about him when on his travels, in the popular sense, by turning his head

J. Hopkins Walters

1873-01-01

64

The Influence of Presumed Media Influence on Women’s Desire to Be Thin  

Microsoft Academic Search

This study investigated the effect of magazine use on the desire to be thin within the theoretical framework of presumed influence. Structural equation modeling supported the hypothesis that reading beauty and fashion magazines increased the drive for thinness both directly and indirectly. The indirect pathway included the perceived prevalence of the thin ideal in mass media, the presumed influence of

Sung-Yeon Park

2005-01-01

65

Is That Dog a Pit Bull? A Cross-Country Comparison of Perceptions of Shelter Workers Regarding Breed Identification  

PubMed Central

Bull breeds are commonly kept as companion animals, but the pit bull terrier is restricted by breed-specific legislation (BSL) in parts of the United States and throughout the United Kingdom. Shelter workers must decide which breed(s) a dog is. This decision may influence the dog's fate, particularly in places with BSL. In this study, shelter workers in the United States and United Kingdom were shown pictures of 20 dogs and were asked what breed each dog was, how they determined each dog's breed, whether each dog was a pit bull, and what they expected the fate of each dog to be. There was much variation in responses both between and within the United States and United Kingdom. UK participants frequently labeled dogs commonly considered by U.S. participants to be pit bulls as Staffordshire bull terriers. UK participants were more likely to say their shelters would euthanize dogs deemed to be pit bulls. Most participants noted using dogs' physical features to determine breed, and 41% affected by BSL indicated they would knowingly mislabel a dog of a restricted breed, presumably to increase the dog's adoption chances. PMID:24673506

Hoffman, Christy L.; Harrison, Natalie; Wolff, London; Westgarth, Carri

2014-01-01

66

20 CFR 404.721 - Evidence to presume a person is dead.  

Code of Federal Regulations, 2010 CFR

...Benefits 2 2010-04-01 2010-04-01 false Evidence to presume a person is dead. 404.721 Section...OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Evidence Evidence of Age, Marriage, and Death § 404.721...

2010-04-01

67

A Witnessed Short Fall Mimicking Presumed Shaken Baby Syndrome (Inflicted Childhood Neurotrauma)1  

Microsoft Academic Search

A witnessed fall backwards of an infant from a sitting position resulted in the subdural hematoma and retinal hemorrhages characteristic of presumed shaken baby syndrome. Violent shaking is not necessary to produce these findings.

Horace B. Gardner

2007-01-01

68

Tularaemia in Norwegian dogs.  

PubMed

We describe tularaemia in a Norwegian dog caused by Francisella tularensis subspecies holarctica. A Hamilton Hound and his owner developed tulaeremia after hunting an infected mountain hare (Lepus timidus). The dog showed signs of lethargy, anorexia and fever during a period two to four days after hunting and thereafter fully recovered. Its antibody titers increased 32-fold from one to three weeks post exposure. Thereafter, the titer declined and leveled off at moderate positive values up to one year after exposure (end of study). This is believed to be the first case report of clinical F. tularensis subspecies holarctica infection in a European dog. In 2011, enormous numbers of Norway lemmings (Lemmus lemmus) occurred in Finnmark, the northernmost county of Norway and many dogs caught and swallowed lemmings. Some of these dogs developed non-specific signs of disease and the owners consulted a veterinary surgeon, who suspected tularaemia. In order to investigate this hypothesis, serum samples from 33 dogs were examined for antibodies to F. tularensis. The dogs were allocated into three groups: Dogs from Finnmark that became sick (Group 1) or remained healthy following contact with lemmings (Group 2), and healthy control dogs from Oslo without known contact with lemmings (Group 3). All the serum samples were analyzed with a tube agglutination assay. Among dogs exposed to lemmings, 10/11 and 3/12 were antibody positive in Group 1 and Group 2, respectively, whereas none of the control dogs (n=10) were positive for antibodies against F. tularensis. These results strongly indicate that the non-specific disease seen in the dogs in Finnmark was linked to F. tularensis infection acquired through contact with lemmings. PMID:25150161

Nordstoga, Anne; Handeland, Kjell; Johansen, Tone Bjordal; Iversen, Lena; Gavier-Widén, Dolores; Mattsson, Roland; Wik-Larssen, Kjersti; Afset, Jan Egil; Nćverdal, Rune; Lund, Arve

2014-10-10

69

Circovirus in Dogs FAQ  

MedlinePLUS

... a good outcome for that dog. Although we still have a lot to learn about this circovirus, there’s no cause for panic. We know that dogs infected with circovirus don’t always become ill, but we don’t know how much of ...

70

Do Dogs Know Bifurcations?  

ERIC Educational Resources Information Center

When a dog (in this case, Tim Pennings' dog Elvis) is in the water and a ball is thrown downshore, it must choose to swim directly to the ball or first swim to shore. The mathematical analysis of this problem leads to the computation of bifurcation points at which the optimal strategy changes.

Minton, Roland; Pennings, Timothy J.

2007-01-01

71

Dogs Over Babies  

E-print Network

wee babe you find a wee dog. In a frilly t-shirt. Meet Japan's newest demographic: Career-oriented women who choose dogs instead of babies, careers instead of motherhood. These women spend big bucks on doggie accessories, doggie parties and doggie spas...

Hacker, Randi; Tsutsui, William

2007-08-19

72

One Dog Policy  

E-print Network

Broadcast Transcript: First the one child policy and now the one dog policy. First in Beijing and now in Guangzhou, the government is limiting the number of dogs in any household to one. And the regulation wasn't grandfathered in, meaning if you had...

Hacker, Randi

2009-08-19

73

Can Dogs Reason?  

Microsoft Academic Search

DR. HILL has recently asked the question, ``Can dogs reason?'' The following analogy has always appeared to me to be a sufficient reply. In ordinary circumstances, few human beings make use of their sense of smell; to excite it, the odour must be fairly strong, and also unusual. It may be regarded as probable that few dogs make habitual use

William Ramsay

1903-01-01

74

[Raising fighting dogs].  

PubMed

Some experience is reported, referring to court trials of accidents involving members of the so-called "fighting dog" breeds. Analysis of the situation makes obvious that many breeders and owners of these or similar dogs demonstrate an irresponsible attitude, thereby fostering breed standards which should be corrected. A future solution of this problem and of others could only be brought about by a law, which would regulate companion animal breeding and ownership. A ban on special breeds or their integration into a "Dangerous animals act" seems for now to be feasible for breeds only which are explicitly standard-bred for aggressiveness against man. Responsible dog breeding and ownership is postulated in order to avoid a growing aversion against dogs in society, which certainly contributed to the stagnation of the dog population in the FRG during the last years. PMID:2351054

Wegner, W

1990-04-01

75

The Discourse of Dog Fighting  

Microsoft Academic Search

In this essay, we discuss dog fighting as a blood sport with a history embedded in the status-driven display of masculinity, power and violence. Based on published reports and interviews with those living and working in dog fighting neighborhoods, we show that the contemporary cultural knowledge of dog fighting is a discourse with multiple meanings: for those who pit dogs

Linda Kalof; Carl Taylor

2007-01-01

76

Dogs Are Not for Dinner  

E-print Network

Broadcast Transcript: Dogs. They're not just for dinner anymore. Over the years, many a Chinese diner has cooked and served dog and there's a story about an emperor from ancient times whose favorite meat was dog meat. And while dog is still...

Hacker, Randi

2011-02-23

77

Animal Planet: Dog Breed Directory  

NSDL National Science Digital Library

Are you considering bringing a canine into the family, and wondering which type of dog would be the best fit? This website from Animal Planet provides potential dog owners with information about a variety of breeds. The site directory lists dogs under such categories as Hound, Sporting, Terrier, Working, Herding, and more. Site visitors can view profiles for many different types of dogs including the Bernese Mountain Dog, Irish Setter, Old English Sheepdog, and Tibetan Spaniel. Dog profiles contain a photograph, Rating of Characteristics; and concise sections addressing History, Temperament, Form and Function, Upkeep, and Health. Profiles also include a hyperlinked list of related dogs.

78

Is helmet CPAP first line pre-hospital treatment of presumed severe acute pulmonary edema?  

Microsoft Academic Search

Purpose  Non-invasive continuous positive airway pressure (CPAP) is effective in reducing intubation rate and mortality of patient\\u000a with acute cardiogenic pulmonary edema (ACPE). We report our experience on pre-hospital application of CPAP by helmet as an\\u000a adjunct to medical therapy or as a stand alone procedure in patient with presumed ACPE.\\u000a \\u000a \\u000a \\u000a Methods  In pre-hospital treatment of 62 patients with presumed ACPE, CPAP

Giuseppe Foti; Fabio Sangalli; Lorenzo Berra; Stefano Sironi; Marco Cazzaniga; Gian Piera Rossi; Giacomo Bellani; Antonio Pesenti

2009-01-01

79

Dogs discriminate identical twins.  

PubMed

Earlier studies have shown variation among experimental attempts to establish whether human monozygotic twins that are genetically identical also have identical individual scents. In none of the cases were the dogs able to distinguish all the individual scents of monozygotic twins living in the same environment if the scents were presented to them separately. Ten specially trained police German Shepherd dogs of three Czech Republic Police Regional Headquarters were used for scent identification in our study. The dogs were supposed to match scents of two monozygotic pairs (5 and 7 years old) and two dizygotic twin pairs (8 and 13 years old). Scents were collected on cotton squares stored in glass jars. Dog handlers were blind to the experiment details. In each trial (line-up), one scent was used as a starting scent and the dog was then sent to determine if any of the 7 presented glass jars contained a matching scent. Scents of children of similar ages were used as distractors. In the matching procedure, the dogs matched correctly the scent of one twin with the other, as well as two scents collected from every single identical and non-identical twin to prove their efficacy and likewise, the presence of the matching twin scent in any given glass jar. All dogs in all trials distinguished correctly the scents of identical as well as non-identical twins. All dogs similarly matched positively two scents collected from the same individuals. Our findings indicated that specially trained German Shepherd dogs are able to distinguish individual scents of identical twins despite the fact that they live in the same environment, eat the same food and even if the scents are not presented to them simultaneously. PMID:21698282

Pinc, Ludvík; Bartoš, Lud?k; Reslová, Alice; Kotrba, Radim

2011-01-01

80

Molecular diagnosis of diphyllobothriasis in Spain, most presumably acquired via imported fish, or sojourn abroad  

PubMed Central

Human diphyllobothriasis is sporadically detected in Spain. Diphyllobothrium latum and Diplogonoporus balaenopterae have been identified. In the study, four cases of presumably imported diphyllobothriasis in Spanish patients were appraised. Molecular diagnosis allowed us to identify ‘exotic’ fish tapeworms such as Diplogonoporus balaenopterae in one patient and Diphyllobothrium pacificum in the others. PMID:25356331

Pastor-Valle, J; Gonzalez, L M; Martin-Clemente, J P; Merino, F J; Gottstein, B; Garate, T

2014-01-01

81

Dark-maned males are presumably better able to withstand heat-related costs, and  

E-print Network

Dark-maned males are presumably better able to withstand heat-related costs, and although we could find no heritability in darkness, mate choice for dark manes might confer indirect genetic benefits. 18, 245 (1995). 32. These results might reflect variations in diet or vegetation. Food supply is most

Terasaki, Mark

82

From Presumed Benefit to Potential Harm — Hormone Therapy and Heart Disease  

Microsoft Academic Search

During the past decade, postmenopausal hormone therapy became one of the most frequently pre- scribed therapies in the United States, with a highly diversified portfolio of presumed benefits for post- menopausal women. The belief that hormone ther- apy might reduce a woman's risk of coronary heart disease contributed considerably to its widespread use. Beginning in 1998, results from a series

David M. Herrington; Timothy D. Howard

2003-01-01

83

Perissomyrmexmontlcola n.sp.. from Bhutan: the first natural record fora presumed Neotropical  

E-print Network

Perissomyrmexmontlcola n.sp.. from Bhutan: the first natural record fora presumed Neotropical genus i & t . Rhitnpwrrg 9. CH-4051h c l , h i & Pnir- mom~ohn. rp. is d c s c r i from Bhutan on three kcn mded horn Guattrmlp dY.The discowry ot P. monrlroh in Bhutan, Er MU M the +!c phylttic rc

Villemant, Claire

84

Neural network detected in a presumed vestigial trait: ultrastructure of the  

E-print Network

of interconnected astrocyte-like cells equipped with primary cilia. The fin contains neither adipose tissue nor finNeural network detected in a presumed vestigial trait: ultrastructure of the salmonid adipose fin J function was not recognized. The adipose fin is small, fleshy, non-rayed and located between the dorsal

Reimchen, Thomas E.

85

Jealousy in Dogs  

PubMed Central

It is commonly assumed that jealousy is unique to humans, partially because of the complex cognitions often involved in this emotion. However, from a functional perspective, one might expect that an emotion that evolved to protect social bonds from interlopers might exist in other social species, particularly one as cognitively sophisticated as the dog. The current experiment adapted a paradigm from human infant studies to examine jealousy in domestic dogs. We found that dogs exhibited significantly more jealous behaviors (e.g., snapping, getting between the owner and object, pushing/touching the object/owner) when their owners displayed affectionate behaviors towards what appeared to be another dog as compared to nonsocial objects. These results lend support to the hypothesis that jealousy has some “primordial” form that exists in human infants and in at least one other social species besides humans. PMID:25054800

Harris, Christine R.; Prouvost, Caroline

2014-01-01

86

Biliary excretion of technetium-99m-sestamibi in wild-type dogs and in dogs with intrinsic (ABCB1-1Delta mutation) and extrinsic (ketoconazole treated) P-glycoprotein deficiency.  

PubMed

P-glycoprotein (P-gp), the product of ABCB1 gene, is thought to play a role in the biliary excretion of a variety of drugs, but specific studies in dogs have not been performed. Because a number of endogenous (ABCB1 polymorphisms) and exogenous (pharmacological P-gp inhibition) factors can interfere with normal P-gp function, a better understanding of P-gp's role in biliary drug excretion is crucial in preventing adverse drug reactions and drug-drug interactions in dogs. The objectives of this study were to compare biliary excretion of technetium-99m-sestamibi ((99m)Tc-MIBI), a radio-labelled P-gp substrate, in wild-type dogs (ABCB1 wild/wild), and dogs with intrinsic and extrinsic deficiencies in P-gp function. Dogs with intrinsic P-gp deficiency included ABCB1 mut/mut dogs, and dogs with presumed intermediate P-gp phenotype (ABCB1 mut/wild). Dogs with extrinsic P-gp deficiency were considered to be ABCB1 wild/wild dogs treated with the P-gp inhibitor ketoconazole (5 mg/kg PO q12h x 9 doses). Results from this study indicate that ABCB1 mut/mut dogs have significantly decreased biliary excretion of (99m)Tc-MIBI compared with ABCB1 wild/wild dogs. Treatment with ketoconazole significantly decreased biliary excretion of (99m)Tc-MIBI in ABCB1 wild/wild dogs. P-gp appears to play an important role in the biliary excretion of (99m)Tc-MIBI in dogs. It is likely that concurrent administration of a P-gp inhibitor such as ketoconazole will decrease P-gp-mediated biliary excretion of other substrate drugs as well. PMID:19754906

Coelho, J C; Tucker, R; Mattoon, J; Roberts, G; Waiting, D K; Mealey, K L

2009-10-01

87

[Exaggerated breed characteristics in dogs].  

PubMed

Dutch dog owners seem to be aware of bad dog breeding practices with regard to exaggerated breed characteristics that are detrimental to the dog's welfare. Yet they do not always look for these features when buying a dog. Most dog owners think that veterinarians could have an important role in preventing these exaggerated physical traits, by providing information about these traits and taking action in their capacity as veterinarian. Articles 36 and 55 of the Dutch GWWD (animal health and welfare law) provide opportunities to act against the breeding of dogs with exaggerated genetic traits. PMID:22372054

Wilting, M M; Endenburg, N

2012-01-01

88

Prairie dog care and husbandry.  

PubMed

The species of prairie dog most commonly found in the pet trade is the black-tailed prairie dog, Cynomus ludovicianus. These prairie dogs are active, playful, and strong rodents that can make wonderful, affectionate pets when they are properly socialized and given attention. However, with a life span of 8 to 12 years, prairie dogs require a lot of care and a long-term commitment. Prairie dogs live in colonies; thus, they are highly social animals. Potential owners should understand a prairie dog's need for attention before adopting one. PMID:15145390

Pilny, Anthony A; Hess, Laurie

2004-05-01

89

4-H Dog Project Record Grade in Date  

E-print Network

4-H Dog Project Record Grade in Date Name___________________________________ Boy _____ Girl a photo of you & your dog in this space. Information about Your Dog My dog's name dog registered in American Kennel Club American Field Other ___________________ Dog's age _______ Year

Tullos, Desiree

90

Treating Cushing's Disease in Dogs  

MedlinePLUS

... on top of the kidneys. Dogs, cats, and horses, as well as humans, can get Cushing's disease. ... commonly found in dogs than in cats or horses. "Cortisol is one of the body's natural steroids," ...

91

Black-Tailed Prairie Dog  

USGS Multimedia Gallery

Black-tailed prairie dogs are quite susceptible to sylvatic plague, but a new plague vaccine put in their food shows significant promise in the laboratory. The prairie dogs transmit the disease to endangered black-footed ferrets, who eat the prairie dogs and are also quite susceptible to the disease...

2009-08-03

92

Biting dogs in Rome (Italy)  

Microsoft Academic Search

We present data on dog biting events which occurred in Rome and were recorded by the Public Dog Shelter and Veterinary Hospital of Rome. In Italy the control of rabies is regulated by Presidential Decree. Recently, the endorsement of a National Law, aimed at the prevention of dog and cat straying, has greatly modified the relationship with, and the management

L. Maragliano; G. Ciccone; C. Fantini; C. Petrangeli; G. Saporito; M. Di Traglia; E. Natoli

2007-01-01

93

Dog Feeding and By: Jennifer Cooper  

E-print Network

Dog Feeding and Care By: Jennifer Cooper Trista Anderson Animal Science 405 Applied Animal://www.aspca.org/pet-care/ dog-care/feeding-your- puppy.html http://www.aspca.org/pet-care/ dog-care/dog-care-newborn- puppy-care.html http://www.aspca.org/pet-care/ dog-care/feeding-your-adult- dog.html http://www.hsus.org/pets/ pet_care/dog

Selmic, Sandra

94

Dinoseb toxicosis in two dogs.  

PubMed

Two male English Setters were noticed to be breathing rapidly, hyperexcitable, and atactic after roaming a rural area for 2 hours. Both dogs' cost were stained with yellow liquid. One dog died while en route to the veterinarian. Treatment was begun for the surviving dog for what was initially diagnosed to be organophosphorus or carbamate insecticide toxicosis. Before the diagnosis could be confirmed, the second dog died. The yellow liquid on the dogs' skin was identified as dinoseb in high concentrations. Dinoseb is an acutely toxic, substituted dinitrophenolic herbicide believed to act as an uncoupler of electron transport from oxidative phosphorylation. PMID:2921205

Fikes, J D; Lovell, R A; Metzler, M; Buck, W B

1989-02-15

95

Antimicrobial management of presumed microbial keratitis: guidelines for treatment of central and peripheral ulcers  

PubMed Central

AIMS—To determine the quantitative relation between the major risk factors for microbial keratitis of previous ocular surface disease and contact lens wear and central and peripheral infiltration, often associated with ulceration, in order to establish a rational chemotherapeutic management algorithm.?METHODS—Data from 55 patients were collected over a 10 month period. All cases of presumed microbial keratitis where corneal scrapes had been subjected to microbiological examination were included. Risk factor data and laboratory outcome were recorded. Antimicrobial regimens used to treat each patient were documented.?RESULTS—57 episodes of presumed microbial keratitis were identified from 55 patients, 24 male and 31 female. There were 30 central infiltrates and 27 peripheral infiltrates of which 28 were culture positive (73% of central infiltrates, 22% of peripheral infiltrates). 26 patients had worn contact lenses of whom 12 had culture positive scrapes (9/14 for central infiltrates, 3/12 for peripheral infiltrates). 31 patients had an ocular surface disease of whom five previous herpes simplex virus keratitis patients developed secondary bacterial infection. Anterior chamber activity and an infiltrate size ? 4 mm2 were more common with culture positive central infiltrates than peripheral infiltrates (?2 test = 11.98, p<0.001).?CONCLUSIONS—Predisposing factors for "presumed" microbial keratitis, either central or peripheral, were: ocular surface disease (26/57 = 45.6%), contact lens wear (26/57 = 45.6%), and previous trauma (5/57 = 8.8%). Larger ulceration (?4 mm2) with inflammation was more often associated with positive culture results for central infiltration. None of these four variables (contact lens wear, ocular surface disease, ulcer size, anterior chamber activity) were of intrinsic value in predicting if a peripheral infiltrate would yield identifiable micro-organisms. Successful management of presumed microbial keratitis is aided by a logical approach to therapy, with the use of a defined algorithm of first and second line broad spectrum antimicrobials, for application at each stage of the investigative and treatment process considering central and peripheral infiltration separately.?? Keywords: ulcerative keratitis; antimicrobials; ulcers PMID:9613378

Bennett, H; Hay, J; Kirkness, C; Seal, D; Devonshire, P.

1998-01-01

96

Sudden unexplained hemolysis occurring in an infant due to presumed Loxosceles envenomation.  

PubMed

We report the case of a 3-week-old infant referred for evaluation of sudden onset jaundice and unexplained hemolysis. After an exhaustive workup, the most likely etiology was found to be envenomation by a brown recluse spider, Loxosceles reclusa. This case underscores the fact that severe loxoscelism may occur in the absence of the classically described necrotic cutaneous lesion, and represents one of the youngest presumed cases of loxoscelism. We present the case to illustrate the importance of considering loxoscelism in the differential diagnosis of sudden massive hemolysis in children, particularly in endemic areas of the midwestern and southern United States. PMID:14585455

Hostetler, Mark A; Dribben, William; Wilson, David B; Grossman, William J

2003-10-01

97

[Epidemiological aspects of dog bites].  

PubMed

Animal bites in humans are an important public health problem. Most of these bites are dog bites. The first step in preventing this kind of accident is to identify the associated risk factors. The present article reviews the most important published articles on the incidence of dog bites, their risk factors, and preventive measures. Concerning victim profiles, features such as age, sex, location, and the severity of the wounds are reviewed. Regarding dogs, the most frequent breeds involved and the dog's previous history of aggression are described. In addition, the different contexts in which bites occur are reported. Thus, factors such as dates, number of dogs, places, victim-dog relationship and interaction, and the distinct involved categories of aggression of the canine ethogram are reviewed. The most frequent recommendations found in the literature to reduce and prevent dog bites in the human population are also described. PMID:15745669

Palacio, Jorge; León, Marta; García-Belenguer, Sylvia

2005-01-01

98

Food of the dogs  

Microsoft Academic Search

Once again, while Greg is slacking off on vacation, his two dogs, Mink and Clifford, nobly pitch in to keep his column going. For those of you who have not met them previously (they are semi-regulars to these pages), Mink is a brave, loyal, intelligent chocolate Labrador retriever whose duties include guarding the house and watching over the family by

Gregory A Petsko

2011-01-01

99

Glow Dog Glow  

E-print Network

Broadcast Transcript: South Korean researchers, ever striving to be top in science, have cloned a glow-in-the-dark dog. The little beagle was engineered by inserting genes from species--like jellyfish--that produce fluorescent proteins. The gene...

Hacker, Randi

2011-08-17

100

Hot Dog Champ Defeated  

E-print Network

Broadcast Transcript: Arthritic jaw? Recent wisdom tooth extraction? The universe saying "It is time"? Whatever. All we know is that Japan's six year domination of Nathan's Famous July 4th Hot Dog Eating contest at Coney Island came to an end...

Hacker, Randi; Tsutsui, William; Bleier, R.H.

2007-07-25

101

Zen Hot Dog Molecules  

ERIC Educational Resources Information Center

Substituted cycloalkanes with one branch illustrating each topic in an instructional unit can serve as summaries or reviews in courses of organic chemistry. The hungry Zen master told the hot dog vendor to make him one with everything. You can do the same for your students.

Ryan, Dennis

2009-01-01

102

Protothecosis in a dog.  

PubMed

A case of a disseminated algal infection is reported in a young rough-coated collie dog with progressive neurologic deficits, blindness, and hemorrhagic diarrhea. Prototheca zopfii organisms were cultured from feces, urine, and blood. At necropsy, granulomas containing typical organisms were identified within the proximal colon, heart, kidneys, and eyes. PMID:25320382

Vince, Andrew R; Pinard, Chantale; Ogilvie, Adam T; Tan, Emmeline O; Abrams-Ogg, Anthony C G

2014-10-01

103

Inflammatory autoimmune neuropathy, presumably induced by bortezomib, in a patient suffering from multiple myeloma.  

PubMed

Bortezomib is a proteasome inhibitor demonstrating substantial activity in multiple myeloma. One of its key toxicities is peripheral neuropathy, which is reversible in most patients. The possibility that bortezomib might in rare cases induce severe neuropathies by auto-inflammatory mechanisms remains controversial. We report here the case of a 65-year-old female myeloma patient who was initially treated with bortezomib, doxorubicin, and dexamethasone (PAD). At the end of the second cycle of PAD, the patient presented with a rapid and severe onset of paresis of the left arm, accompanied by progressive sensory neuropathy and increasing neuropathic pain. After an extensive neurological work-up, including electrophysiological and laboratory evaluations as well as magnet resonance tomography imaging, we diagnosed an inflammatory autoimmune neuropathy, presumably induced by bortezomib, with accentuation of the left arm nerve plexus. We subsequently initiated regular treatment with polyvalent immunoglobulins, which gradually improved the neurological symptoms. In conclusion, the identification of an inflammatory autoimmune neuropathy, presumably associated with bortezomib, is a rare but important complication. An extensive neurological examination should be performed in patients who develop severe or unusual sensory or motor deficits under therapy with bortezomib, so as to differentiate autoimmune from toxic neuropathies, as therapeutic strategies differ for each. PMID:21553020

Schmitt, Stefan; Goldschmidt, H; Storch-Hagenlocher, B; Pham, M; Fingerle-Rowson, G; Ho, A D; Neben, K

2011-06-01

104

WASHINGTON STATE 4-H DOG OBEDIENCE PROGRAM NOVICE TEAMSCORE SHEET  

E-print Network

.... Long Down (3 minutes) Down your dog Leave your dog Back to your dog Exercise finished Long Sit (1 minute) Sit your dog Leave your dog Back to your dog Exercise finished Did not remain in place Leave your dog Call your dog Finish Exercise finished Extra command or signal to stay

New Hampshire, University of

105

Sex ratios of Dirofilaria immitis in naturally infected dogs show female bias at low worm intensities.  

PubMed

Sex ratios in invertebrates commonly deviate from parity (1:1). Various genetic and epigenetic factors distort sex ratios to favor males or females. We examined sex ratios in Dirofilaria immitis (heartworms) obtained from naturally-infected dogs. Dirofilaria from 84 naturally-infected pound-source dogs were extracted at necropsy, counted and sexed. Dogs had a median worm intensity of 15 filariae. Overall, sex ratios equaled 1. However, at low worm intensities, dogs were more likely to have female than male worms. Of eight unisex infections, seven were all-female (range 1-11 worms), while only one dog had a single male worm. Similarly, in mixed-sex infection at worm intensities<20 worms, dogs were more likely to have more female worms than male worms. Our results suggest that sex disequilibrium exists in D. immitis at lower worm intensities, but disappears with higher worm intensities. Reasons for this disequilibrium are unknown, but presumably confer a species survival advantage. PMID:22819731

Rishniw, Mark; Schukken, Ynte; Greiner, Ellis

2012-12-01

106

Presumed intramedullary spinal cord sarcoidosis in a healthy young adult woman.  

PubMed

Sarcoidosis is an inflammatory disease of unknown etiology associated with the development of granulomatous nodules in various organs, most commonly the lungs, eyes, and skin. It rarely affects the central nervous system, with the spinal cord being least common area of involvement. However, when sarcoidosis does affect the central nervous system, it is often the first presentation of the disease, making diagnosis more difficult. Physical examination findings are consistent with spinal cord pathology, and imaging often suggests spinal cord tumor. We present a case of an otherwise healthy young woman with a granulomatous mass in her cervico-thoracic spinal cord presumed to be sarcoid and review the clinical findings, diagnosis, treatment, and prognosis associated with this rare disease. PMID:22257972

Eby, Sarah A; Buchner, Eric J; Bryant, Mary G

2012-09-01

107

New Hampshire Guide 4-H Dog Shows  

E-print Network

New Hampshire Guide to 4-H Dog Shows UNH Cooperative Extension 4-H Youth Development Moiles House cooperating. #12;NH Guide to 4-H Dog Shows i Table of Contents INTRODUCTION .................................................................................................................................2 Purpose of the 4-H Dog Project

New Hampshire, University of

108

Dogs steal in the dark.  

PubMed

All current evidence of visual perspective taking in dogs can possibly be explained by dogs reacting to certain stimuli rather than understanding what others see. In the current study, we set up a situation in which contextual information and social cues are in conflict. A human always forbade the dog from taking a piece of food. The part of the room being illuminated was then varied, for example, either the area where the human was seated or the area where the food was located was lit. Results show that dogs steal significantly more food when it is dark compared to when it is light. While stealing forbidden food the dog's behaviour also depends on the type of illumination in the room. Illumination around the food, but not the human, affected the dogs' behaviour. This indicates that dogs do not take the sight of the human as a signal to avoid the food. It also cannot be explained by a low-level associative rule of avoiding illuminated food which dogs actually approach faster when they are in private. The current finding therefore raises the possibility that dogs take into account the human's visual access to the food while making their decision to steal it. PMID:23179109

Kaminski, Juliane; Pitsch, Andrea; Tomasello, Michael

2013-05-01

109

41 CFR 301-72.1 - Why is common carrier presumed to be the most advantageous method of transportation?  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Why is common carrier presumed to be the most advantageous...RESPONSIBILITIES 72-AGENCY RESPONSIBILITIES RELATED TO COMMON CARRIER TRANSPORTATION Procurement of Common Carrier Transportation § 301-72.1...

2010-07-01

110

Chronic pancreatitis in dogs.  

PubMed

Chronic pancreatitis used to be considered uncommon in dogs, but recent pathological and clinical studies have confirmed that it is in fact a common and clinically significant disease. Clinical signs can vary from low-grade recurrent gastrointestinal signs to acute exacerbations that are indistinguishable from classical acute pancreatitis. Chronic pancreatitis is a significant cause of chronic pain in dogs, which must not be underestimated. It also results in progressive impairment of endocrine and exocrine function and the eventual development of diabetes mellitus or exocrine pancreatic insufficiency or both in some affected dogs at end stage. The etiology is unknown in most cases. Chronic pancreatitis shows an increased prevalence in certain breeds, and recent work in English Cocker Spaniels suggests it is part of a polysystemic immune-mediated disease in this breed. The histological and clinical appearance is different in different breeds, suggesting that etiologies may also be different. Diagnosis is challenging because the sensitivities of the available noninvasive tests are relatively low. However, with an increased index of suspicion, clinicians will recognize more cases that will allow them to institute supportive treatment to improve the quality of life of the patient. PMID:23148854

Watson, Penny

2012-08-01

111

Obesity in show dogs.  

PubMed

Obesity is an important disease with a growing incidence. Because obesity is related to several other diseases, and decreases life span, it is important to identify the population at risk. Several risk factors for obesity have been described in the literature. A higher incidence of obesity in certain breeds is often suggested. The aim of this study was to determine whether obesity occurs more often in certain breeds. The second aim was to relate the increased prevalence of obesity in certain breeds to the official standards of that breed. To this end, we investigated 1379 dogs of 128 different breeds by determining their body condition score (BCS). Overall, 18.6% of the show dogs had a BCS >5, and 1.1% of the show dogs had a BCS>7. There were significant differences between breeds, which could be correlated to the breed standards. It warrants firm discussions with breeders and judges in order to come to different interpretations of the standards to prevent overweight conditions from being the standard of beauty. PMID:22882163

Corbee, R J

2012-08-11

112

Lycoperdonosis in two dogs.  

PubMed

Lycoperdonosis is a rare respiratory disease that results from the inhalation of spores released from the Lycoperdon (puffball) mushroom. In the present study, 2 cases of confirmed canine lycoperdonosis are described. The first case presented to the Matthew J. Ryan Veterinary Hospital of the University of Pennsylvania, and the second case was submitted for postmortem examination to the University of Tennessee Veterinary Teaching Hospital. Both dogs presented in respiratory distress, and owners reported that the dogs had been playing or digging in areas with puffball mushrooms prior to the onset of clinical signs. In the initial case, thoracic radiographs revealed a diffuse interstitial and multifocal alveolar pulmonary pattern. Despite aggressive medical treatment and mechanical ventilation, the dog continued to worsen and was euthanized. Postmortem examination revealed firm lung lobes and enlarged tracheobronchial lymph nodes. Histologically, there was a severe diffuse histiocytic and pyogranulomatous bronchointerstitial pneumonia. Throughout the lung and lymph nodes, most commonly within macrophages, were round, 3-5 µm in diameter, Gomori methenamine silver-positive structures, consistent with Lycoperdon spores. An approximately 750-base pair DNA fragment was amplified from lung of both cases by polymerase chain reaction using primers specific to yeast ribosomal DNA, and the sequence of the fragment was determined to be most closely related to Lycoperdon pyriforme. Importantly, reexamination of an endotracheal wash from the initial case revealed intrahistiocytic spores, suggesting that airway sampling may assist in diagnosing lycoperdonosis. PMID:21088194

Alenghat, Theresa; Pillitteri, Cara A; Bemis, David A; Kellett-Gregory, Lindsay; Jackson, Karen V; Kania, Stephen A; Donnell, Robert L; Van Winkle, Thomas

2010-11-01

113

Using dogs for tiger conservation and research.  

PubMed

This paper is a review of the history, development and efficacy of using dogs in wildlife studies and considers the use of dogs in the research and conservation of wild tigers (Panthera tigris Linnaeus, 1758). Using scat detection dogs, scent-matching dogs, law enforcement detection dogs and protection dogs are proven methods that can be effectively used on tigers. These methods all take advantage of the dog's extremely evolved sense of smell that allows them to detect animals or animal byproducts (often the focus of tiger studies). Dogs can be trained to communicate this information to their handlers. PMID:21392356

Kerley, Linda L

2010-12-01

114

Collection Development "Dog Care & Training": The Well-Behaved Dog  

ERIC Educational Resources Information Center

Dogs are indeed people's best friends. A majority of owners report that their dog is a "member of the family," and that acceptable canine behavior and optimal care are high priorities for them. The human-animal bond, the close connection between people and their pets, is forged by positive interactions, but unacceptable canine behaviors that…

Alpi, Kristine M.; Sherman, Barbara L.

2008-01-01

115

[Fighting dogs--dangerous dogs: legal situation in Bavaria].  

PubMed

A report is given on eight years of experience with the Bavarian legal regulation for the protection against dangerous dogs of 10.7.1992. The implementation of the regulation was a success. Since then only two cases of biting accidents are reported. In one case the dogs were euthanatized, in the other case they were taken away and given to other owners. The advantages of the regulation are seen in the increased responsibility of the dog owner who has to give proof of the peaceful character of his dog in form of an expert testimony. This lowers the administration costs and has revealed a preventive effect, the dog owners are looking more carefully after their animals to avoid any security problems. PMID:11314462

Breitsamer, F

2001-03-01

116

Excimer Laser Phototherapeutic Keratectomy for the Treatment of Clinically Presumed Fungal Keratitis  

PubMed Central

This retrospective study was to evaluate treatment outcomes of excimer laser phototherapeutic keratectomy (PTK) for clinically presumed fungal keratitis. Forty-seven eyes of 47 consecutive patients underwent manual superficial debridement and PTK. All corneal lesions were located in the anterior stroma and were resistant to medication therapy for at least one week. Data were collected by a retrospective chart review with at least six months of follow-up data available. After PTK, infected corneal lesions were completely removed and the clinical symptoms resolved in 41 cases (87.2%). The mean ablation depth was 114.39 ± 45.51??m and diameter of ablation was 4.06 ± 1.07?mm. The mean time for healing of the epithelial defect was 8.8 ± 5.6 days. Thirty-four eyes (82.9%) showed an improvement in best spectacle-corrected visual acuity of two or more lines. PTK complications included mild to moderate corneal haze, hyperopic shift, irregular astigmatism, and thinning cornea. Six eyes (12.8%) still showed progressed infection, and conjunctival flap covering, amniotic membrane transplantation, or penetrating keratoplasty were given. PTK is a valuable therapeutic alternative for superficial infectious keratitis. It can effectively eradicate lesions, hasten reepithelialization, and restore and preserve useful visual function. However, the selection of surgery candidates should be conducted carefully. PMID:24891945

Li, Liang-Mao; Zhao, Li-Quan; Qu, Ling-Hui; Li, Peng

2014-01-01

117

A dog in the fight  

Microsoft Academic Search

Holly Hughes’ “A Dog in the Fight” is a queer and feminist literary performance that models a feminist politics of performance that stands as alternative to performances of power that come from the officially anointed space of politics. In this piece, Hughes meditates on the queer relationship between US Presidents and their faithful companions, their dogs. Refusing to jump through

Holly Hughes

2010-01-01

118

Communal nursing in prairie dogs  

Microsoft Academic Search

Within a natural population of blacktailed prairie dogs (Cynomys ludovicianus), 68% of sampled juveniles received milk from foster mothers via communal nursing (Table 1). In proximate terms, communal nursing may result because prairie dog mothers seem unable to discriminate between their own and others' offspring. In ultimate terms, both indirect selection and reduced predation on juveniles resulting from the formation

J. L. Hoogland; R. H. Tamarin; C. K. Levy

1989-01-01

119

2014 NEW MEXICO STATE 4-H DOG SCHOOL What is a Dog School all about?  

E-print Network

2014 NEW MEXICO STATE 4-H DOG SCHOOL What is a Dog School all about? The New Mexico State 4-H Dog School was designed to help 4-H youth become familiar with the 4-H Dog Project. The first two days consists of training sessions for the youth with their dogs in Obedience, Rally-O, Agility, and Showmanship

120

Rotary slot dog  

DOEpatents

A clamp or dog is disclosed which preferably comprises a slotted stepped cylindrical body which is inserted into a hole in a workpiece and then fastened to a base or fixture using a screw which is inserted through the slot. The stepped configuration provides an annular clamping surface which securely clamps the workpiece against the base or fixture. The slotted cylindrical configuration permits adjustment of the workpiece and retaining clamp in any direction, i.e., over 360.degree., relative to the mounting position of the screw in the base or fixture.

Cutburth, Ronald W. (Tracy, CA); Smauley, David A. (Livermore, CA)

1987-01-01

121

Functional MRI in Awake Unrestrained Dogs  

Microsoft Academic Search

Because of dogs' prolonged evolution with humans, many of the canine cognitive skills are thought to represent a selection of traits that make dogs particularly sensitive to human cues. But how does the dog mind actually work? To develop a methodology to answer this question, we trained two dogs to remain motionless for the duration required to collect quality fMRI

Gregory S. Berns; Andrew M. Brooks; Mark Spivak

2012-01-01

122

4-H Sporting Dog Project Member Guide  

E-print Network

program. The program helps young people learn the sport of hunting with dogs by doing activities exposure to sporting dogs, shooting, hunting, and related activities · Enhancedevelopmentofself are interested in how to train sporting dogs for hunting, companionship, and the 4-H Sporting Dog project.This4

Tullos, Desiree

123

Old Tricks, New Dogs: Ethology and Interactive  

E-print Network

1 Old Tricks, New Dogs: Ethology and Interactive Creatures Bruce Mitchell Blumberg Bachelor of Arts:.................................................................................................................................................................... #12;2 Old Tricks, New Dogs: Ethology and Interactive Creatures #12;3 Old Tricks, New Dogs: Ethology on these ideas and used it to build "Silas", a virtual animated dog, as well as other creatures. We believe

124

38 CFR 17.148 - Service dogs.  

...2014-07-01 2014-07-01 false Service dogs. 17.148 Section 17.148 Pensions...Rehabilitative Aids § 17.148 Service dogs. (a) Definitions. For the purposes of this section: Service dogs are guide or service dogs...

2014-07-01

125

Correspondence Dog as an Outgroup to Human  

E-print Network

Correspondence Dog as an Outgroup to Human and Mouse Gerton Lunter In a recent contribution to PLo to human and dog [1], in disagreement with several recent studies suggesting that the dog is an outgroup to the primate­rodent clade [2,3]. The authors' arguments rest on a variety of analyses of human, mouse, and dog

Gerstein, Mark

126

Dog Obedience, Showmanship, and Contest Guide  

E-print Network

Dog Obedience, Showmanship, and Contest Guide 4-H 1202 Revised January 2013 Purpose Obedience and showmanship contests provide an opportunity for you to demonstrate how well you've trained your dog and how you and your dog work as a team. Eligibility You may enter 4-H dog obedience and showmanship trials

New Hampshire, University of

127

German shepherd dog pyoderma: a prospective study of 12 dogs.  

PubMed

Twelve German shepherd dogs, each diagnosed as having a recurrent or refractory deep pyoderma (i.e., German shepherd dog pyoderma [GSP]), were evaluated for several parameters over a six-year period. Results indicated that GSP could be associated with flea allergy dermatitis, atopic dermatitis, food allergy, cell-mediated immunodeficiency, or hypothyroidism, or could be an idiopathic disease. The combination of diseases present for a given dog varied from case to case. Adequate control of the pyoderma was achieved only after each identified underlying disease was treated specifically, along with aggressive concurrent medical therapy using systemic antibiotics and medicated baths. PMID:9204474

Rosser, E J

1997-01-01

128

Dog and cat bites.  

PubMed

Animal bites account for 1% of all emergency department visits in the United States and more than $50 million in health care costs per year. Most animal bites are from a dog, usually one known to the victim. Most dog bite victims are children. Bite wounds should be cleaned, copiously irrigated with normal saline using a 20-mL or larger syringe or a 20-gauge catheter attached to the syringe. The wound should be explored for tendon or bone involvement and possible foreign bodies. Wounds may be closed if cosmetically favorable, such as wounds on the face or gaping wounds. Antibiotic prophylaxis should be considered, especially if there is a high risk of infection, such as with cat bites, with puncture wounds, with wounds to the hand, and in persons who are immunosuppressed. Amoxicillin/clavulanate is the first-line prophylactic antibiotic. The need for rabies prophylaxis should be addressed with any animal bite because even domestic animals are often unvaccinated. Postexposure rabies prophylaxis consists of immune globulin at presentation and vaccination on days 0, 3, 7, and 14. Counseling patients and families about animal safety may help decrease animal bites. In most states, physicians are required by law to report animal bites. PMID:25250997

Ellis, Robert; Ellis, Carrie

2014-08-15

129

Oesophageal foreign bodies in dogs.  

PubMed

The aim of the paper is to present own experience in diagnosis and endoscopic removal of foreign bodies from the oesophagus in dogs. The study was performed on 22 dogs of different breed and sex, aged 7 months to 17 years, with suspicion of a foreign body in the oesophagus. All the dogs were subjected to a radiography of the oesophagus and oesophagoscopy. The most commonly observed clinical signs were regurgitation and swallowing disorders. The best diagnostic method allowing detection of foreign bodies in the oesophagus was esophagoscopy. PMID:24195295

Jankowski, M; Spuzak, J; Kubiak, K; Gli?ska-Suchocka, K; Nicpo?, J

2013-01-01

130

Dog pack attack: hunting humans.  

PubMed

Dog bite-related fatalities, although unusual, accounted for 304 deaths in the United States between 1979 and 1996 and 6 fatalities in Canada between 1994 and 1996. Fatal dog pack attacks and attacks involving human predation are less common. The following describes a dog pack attack on a family of four involving 2 fatalities with predation of the victims. Factors previously identified that contribute to pack attacks and predation, including prior group hunting, social feeding, territorial defense, lack of human interaction, and prey stimuli, are discussed. PMID:10507791

Avis, S P

1999-09-01

131

[Mitochondrial DNA variation in Asian guardian dogs].  

PubMed

The hypervariable site of the mitochondrial DNA (mtDNA) control region has been studied in several sheepdog breeds. The genetic diversity is high in the Central Asian guardian dog and the Northern Caucasian wolf dog (an aboriginal group of breeds) and low in the Caucasian guardian dog. Haplotypes of groups A, B, C, and E/W have been found in Central Asian guardian dogs; haplotypes of groups A and B, in Caucasian guardian dogs. There is evidence suggesting a gene flow from Scandinavian dog populations to the Northern Caucasus. The results of the analysis allow the Caucasian guardian dog, Northern Caucasian wolf dog, Central Asian guardian dog, and the Turkish breeds akbash and kangal to be combined into a single group with an extremely low degree of differentiation. PMID:16915922

Riabinina, O M

2006-07-01

132

9 CFR 93.600 - Importation of dogs.  

Code of Federal Regulations, 2010 CFR

...OF CONVEYANCE AND SHIPPING CONTAINERS Dogs § 93.600 Importation of dogs. (a) All dogs. Dogs from Angola, Argentina, Bahrain, Bangladesh, Benin, Bolivia, Botswana, Brazil, Brunei, Burkina Faso, Burundi, Cambodia,...

2010-01-01

133

9 CFR 93.600 - Importation of dogs.  

Code of Federal Regulations, 2011 CFR

...OF CONVEYANCE AND SHIPPING CONTAINERS Dogs § 93.600 Importation of dogs. (a) All dogs. Dogs from Angola, Argentina, Bahrain, Bangladesh, Benin, Bolivia, Botswana, Brazil, Brunei, Burkina Faso, Burundi, Cambodia,...

2011-01-01

134

Dog Bites: How to Teach Your Children to Be Safe  

MedlinePLUS

... To learn about dog breeds, talk with a veterinarian, read books about dogs and search the Internet. ... date. Have your dog checked regularly by a veterinarian. What do I tell my children about dogs? ...

135

Low glutathione S -transferase dogs  

Microsoft Academic Search

Liver and kidney glutathione S-transferase (GST) activities to 1,2-dichloro-4-nitrobenzene (DCNB) as a substrate (GST-D activities) were measured in 280 dogs from five different breeders, and significant individual differences in this activity were observed in both organs. Interestingly, 34 out of the 280 dogs (i.e. 12.1%) were those in which liver GST-D activities were less than 10 nmol\\/min per mg cytosolic protein,

Toshiyuki Watanabe; Tomomi Sugiura; Sunao Manabe; Wataru Takasaki; Yoshihiko Ohashi

2004-01-01

136

VSF Dog Department Entry Form 2014 In order to show your dog(s), you must have completed the Dog Approval/Identification form that was due to your Extension  

E-print Network

VSF Dog Department Entry Form 2014 In order to show your dog(s), you must have completed the Dog BE SUBMITTED FOR EACH DOG YOU'RE ENTERING to the UVM Extension Office, 1 Scale Avenue, Suite 55, Rutland, Vermont 05701-4457 ATTN: VSF Dog Department, or scanned and sent as an attachment to mary

Hayden, Nancy J.

137

Performance failure in Alaskan sled dogs: Biochemical correlates  

Microsoft Academic Search

Many dogs competing in long distance sled dog races do not complete the race. In this study the plasma biochemical variables of dogs that completed a long distance sled race were compared with those of dogs that did not complete the race. Blood samples were collected from dogs completing the race and from retired dogs, within six hours of their

K. W Hinchcliff

1996-01-01

138

Introduction There are many varieties of dog collars available to dog  

E-print Network

1 Introduction There are many varieties of dog collars available to dog owners today. The primary purpose of a collar is to provide an effective way for the owner to control his/her dog. In addition collars are appropriate for wear at all times, while others are specifically for walking the dog

139

Comparative Social Cognition of Dogs 26 Comparative Social Cognition: From wolf and dog to humans  

E-print Network

Comparative Social Cognition of Dogs 26 Comparative Social Cognition: From wolf and dog to humans, their natural socialization to humans, and the possibility of tracing evolutionary changes by comparing dogs some dog-specific behaviors, especially with regard to their interactions with humans, by comparing

Indiana University

140

Communication technology for human-dog interaction: exploration of dog owners' experiences and expectations  

Microsoft Academic Search

Whereas communication technology to connect people has long been an integral part of our everyday lives, it has only recently expanded to offer applications for dogs and dog-owners. In this paper, we present two explorative studies to understand the experiences and expectations of dog owners for communication technology to support their interaction with dogs. These studies look at two different

Mikko Paldanius; Tuula Kärkkäinen; Kaisa Väänänen-Vainio-Mattila; Oskar Juhlin; Jonna Häkkilä

2011-01-01

141

Noninvasive radioisotopic technique for detection of platelet deposition in mitral valve prostheses and quantitation of visceral microembolism in dogs  

SciTech Connect

A noninvasive technique has been developed in the dog model for imaging, with a gamma camera, the platelet deposition on Bjoerk-Shiley mitral valve prostheses early postoperatively. At 25 hours after implantation of the prosthesis and 24 hours after intravenous administration of 400 to 500 microCi of platelets labeled with indium-111, the platelet deposition in the sewing ring and perivalvular cardiac tissue can be clearly delineated in a scintiphotograph. An in vitro technique was also developed for quantitation of visceral microemboli in brain, lungs, kidneys, and other tissues. Biodistribution of the labeled platelets was quantitated, and the tissue/blood radioactivity ratio was determined in 22 dogs in four groups: unoperated normal dogs, sham-operated dogs, prosthesis-implanted dogs, and prosthesis-implanted dogs treated with dipyridamole before and aspirin and dipyridamole immediately after operation. Fifteen to 20% of total platelets were consumed as a consequence of the surgical procedure. On quantitation, we found that platelet deposition on the components of the prostheses was significantly reduced in prosthesis-implanted animals treated with dipyridamole and aspirin when compared with prosthesis-implanted, untreated dogs. All prosthesis-implanted animals considered together had a twofold to fourfold increase in tissue/blood radioactivity ratio in comparison with unoperated and sham-operated animals, an indication that the viscera work as filters and trap platelet microemboli that are presumably produced in the region of the mitral valve prostheses. In the dog model, indium-111-labeled platelets thus provide a sensitive marker for noninvasive imaging of platelet deposition on mechanical mitral valve prostheses, in vitro evaluation of platelet microembolism in viscera, in vitro quantitation of surgical consumption of platelets, and evaluation of platelet-inhibitor drugs.

Dewanjee, M.K.; Fuster, V.; Rao, S.A.; Forshaw, P.L.; Kaye, M.P.

1983-05-01

142

Plasma Creatinine Clearance in the Dog  

ERIC Educational Resources Information Center

Lists materials and methods for an experiment that demonstrates the concept of glomerular filtration rate (GFR) using anesthesized dogs. In the dog, GFR is equivalent to the renal plasma clearance of exogenous creatinine. (CS)

Frazier, Loy W.

1977-01-01

143

49 CFR 236.718 - Chart, dog.  

Code of Federal Regulations, 2013 CFR

...Transportation 4 2013-10-01 2013-10-01 false Chart, dog. 236.718 Section 236.718 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.718 Chart, dog. A diagrammatic representation of the mechanical...

2013-10-01

144

49 CFR 236.718 - Chart, dog.  

Code of Federal Regulations, 2010 CFR

...Transportation 4 2010-10-01 2010-10-01 false Chart, dog. 236.718 Section 236.718 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.718 Chart, dog. A diagrammatic representation of the mechanical...

2010-10-01

145

49 CFR 236.718 - Chart, dog.  

Code of Federal Regulations, 2011 CFR

...Transportation 4 2011-10-01 2011-10-01 false Chart, dog. 236.718 Section 236.718 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.718 Chart, dog. A diagrammatic representation of the mechanical...

2011-10-01

146

49 CFR 236.718 - Chart, dog.  

Code of Federal Regulations, 2012 CFR

...Transportation 4 2012-10-01 2012-10-01 false Chart, dog. 236.718 Section 236.718 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.718 Chart, dog. A diagrammatic representation of the mechanical...

2012-10-01

147

Evolutionary history of dog rabies in Brazil.  

PubMed

Although dogs are considered to be the principal transmitter of rabies in Brazil, dog rabies had never been recorded in South America before European colonization. In order to investigate the evolutionary history of dog rabies virus (RABV) in Brazil, we performed a phylogenetic analysis of carnivore RABV isolates from around the world and estimated the divergence times for dog RABV in Brazil. Our estimate for the time of introduction of dog RABV into Brazil was the late-19th to early-20th century, which was later than the colonization period but corresponded to a period of increased immigration from Europe to Brazil. In addition, dog RABVs appeared to have spread to indigenous animals in Brazil during the latter half of the 20th century, when the development and urbanization of Brazil occurred. These results suggest that the movement of rabid dogs, along with human activities since the 19th century, promoted the introduction and expansion of dog RABV in Brazil. PMID:20926638

Kobayashi, Yuki; Suzuki, Yoshiyuki; Itou, Takuya; Ito, Fumio H; Sakai, Takeo; Gojobori, Takashi

2011-01-01

148

Key Facts about Canine Influenza (Dog Flu)  

MedlinePLUS

... dogs, not of humans. What is a canine influenza virus? The â??canine influenza virusâ?ť is an influenza ... Where can I find more information on canine influenza virus? More information on canine influenza in pet dogs ...

149

Examining how presumed media influence affects social norms and adolescents' attitudes and drinking behavior intentions in rural Thailand.  

PubMed

This study uses the influence of presumed media influence model as the theoretical framework to examine how perceived social norms (i.e., descriptive, subjective, and injunctive norms) will mediate the influence of pro- and antidrinking media messages on adolescents' intention to consume alcohol in rural Thailand. Data collected from 1,028 high school students indicate that different mechanisms underlie drinking intentions between nondrinkers and those who have consumed alcohol or currently drink. Among nondrinkers, perceived peer attention to prodrinking messages indirectly influenced adolescents' prodrinking attitudes and intentions to consume alcohol through all three types of perceived social norms. Among drinkers, perceived peer attention to pro- and antidrinking messages indirectly influenced adolescents' prodrinking attitudes and intentions to drink alcohol through perceived subjective norm. The findings provide support for the extended influence of presumed media influence model and have practical implications for how antidrinking campaigns targeted at teenagers in Thailand might be designed. PMID:24354888

Ho, Shirley S; Poorisat, Thanomwong; Neo, Rachel L; Detenber, Benjamin H

2014-01-01

150

Stray Dogs: Danijel Zezelj  

NSDL National Science Digital Library

The website of the Isabella Stewart Gardner Museum in Boston has a digitized version of its contemporary exhibition, from several years ago, that featured the drawings of graphic novelist Danijel Zezelj. The digital exhibition provides a written excerpt of an informative "Interview" with the artist by the curator of the exhibit, and visitors can find the interview under the "Artist Biography" link. To view the exhibition, visitors should click on the "Enter the Exhibition" link, which contains the drawings from the graphic novel "Stray Dogs", but without the accompanying text found in the novel. Each page is an artwork in itself, and contains several seemingly separate drawings per page. The beautiful drawings sometimes resemble paintings or lithographs, with their large swaths of ink. The "Exhibition Details" link is an interesting peek inside the business of lending out a museum exhibit, and visitors will find the criteria for borrowing the work including: the space requirements of the exhibition, the required color of the walls (Autumn Purple by Benjamin Moore), the cost to borrow it from the museum, the cost of multimedia performances related to the exhibit, and the cost of an artist talk.

151

Dark spots in late-phase indocyanine green angiographic studies in a patient with presumed ocular histoplasmosis syndrome  

Microsoft Academic Search

·   Purpose: We analyzed indocyanine green (ICG) angiograms in a patient with presumed ocular histoplasmosis syndrome (POHS)\\u000a complaining about “seeing spots” and decreased visual acuity in order to identify the pathologic process. · Patients and methods:\\u000a A 30-year-old caucasian man with clinical signs of POHS who had previously undergone laser photocoagulation for secondary\\u000a choroidal neovascularization developed visual disturbances primarily in

Andreas W. A. Weinberger; Thomas Kube; S. Wolf

1999-01-01

152

Evaluating the effect of intraoperative peritoneal lavage on bacterial culture in dogs with suspected septic peritonitis  

PubMed Central

This pilot study describes the effect of intraoperative peritoneal lavage (IOPL) on bacterial counts and outcome in clinical cases of septic peritonitis. Intraoperative samples were cultured before and after IOPL. Thirty-three dogs with presumed septic peritonitis on the basis of cytology were managed surgically during the study period. Positive pre-lavage bacterial cultures were found in 14 cases, 13 of which were a result of intestinal leakage. The post-lavage cultures showed fewer isolates in 9 cases and in 1 case became negative. The number of dogs with a decrease in the concentration of bacteria cultured from pre-lavage to post-lavage samples was not statistically significant. There was no significant effect of the change in pre- to post-lavage culture, single versus multiple types of bacteria, selection of an appropriate empiric antimicrobial on survival or the need for subsequent surgery. PMID:23450861

Swayne, Seanna L.; Brisson, Brigitte; Weese, J. Scott; Sears, William

2012-01-01

153

Increased Incidence of Benign Pancreatic Pathology following Pancreaticoduodenectomy for Presumed Malignancy over 10 Years despite Increased Use of Endoscopic Ultrasound  

PubMed Central

Despite using imaging studies, tissue sampling, and serologic tests about 5–10% of surgeries done for presumed pancreatic malignancies will have benign findings on final pathology. Endoscopic ultrasound (EUS) is used with increasing frequency to study pancreatic masses. The aim of this study is to examine the effect of EUS on prevalence of benign diseases undergoing Whipple over the last decade. Patients who underwent Whipple procedure for presumed malignancy at Emory University Hospital from 1998 to 2011 were selected. Demographic data, history of smoking and drinking, history of diabetes and pancreatitis, imaging data, pathology reports, and tumor markers were extracted. 878 patients were found. 95 (10.82%) patients had benign disease. Prevalence of benign finding had increased over the recent years despite using more EUS. Logistic regression models showed that abdominal pain (OR: 5.829, 95% CI 2.681–12.674, P ? 0.001) and alcohol abuse (OR: 3.221, CI 95%: 1.362–7.261, P: 0.002) were predictors of benign diseases. Jaundice (OR: 0.221, 95% CI: 0.084–0.58, P: 0.002), mass (OR: 0.145, 95% CI: 0.043–0.485, P: 0.008), and ductal dilation (OR: 0.297, 95% CI 0.134–0.657, P: 0.003) were associated with malignancy. Use of imaging studies, ERCP, and EUS has not decreased the percentage of benign findings after surgery for presumed pancreatic malignancy. PMID:25002810

Yarandi, Shadi S.; Wang, Lei; Liu, Zhijian; Jiang, Yueping; Woods, Kevin E.; Keilin, Steven; Willingham, Field F.; Xu, Hong; Cai, Qiang

2014-01-01

154

[Biology of aggression in dogs].  

PubMed

The science of ethology is concerned with the way external stimuli and internal events cause animals to fight in a particular way. The classification of dog breeds with respect to their relative danger to humans makes no sense, as both, the complex antecedent conditions in which aggressive behaviour occurs, and its ramifying consequences in the individual dog's ecological and social environment, are not considered. From a biological point of view, environmental and learning effects are always superimposed upon genetic influences. Based on the recent developments in the study of ethology, aggression of wolves (Canis lupus L.) and domesticated dogs (Canis lupus f. familiaris) was put into context with respect to other aspects of the lifestyle of wild and domestic canids. Aggressive behaviour does not occur in a biological vacuum. This is also true for domestic dogs and their relationship to human partners. Individual dogs can become highly aggressive and dangerous. Their development and social situation will be presented and discussed in case studies. Finally, there is the question about defining "normal aggression" versus symptoms for maladaptive aggression resp. danger to humans as conspecifics. It is possible to protect the safety of the public and at the the same time practise animal care. Effective animal control legislation must focus on responsible ownership and socialisation of pups f.e. Problems are not unique to some breeds. PMID:11314475

Feddersen-Petersen, D U

2001-03-01

155

Impact of community-based vector control on house infestation and Trypanosoma cruzi infection in Triatoma infestans, dogs and cats in the Argentine Chaco  

PubMed Central

The relative impact of two community-based vector control strategies on house infestation by Triatoma infestans and Trypanosoma cruzi infection in bugs, domestic dogs and cats was assessed in two neighboring rural areas comprising 40 small villages and 323 houses in one of the regions most endemic for Chagas disease in northern Argentina. The prevalence and abundance of domestic infestation were 1.5- and 6.5-fold higher, respectively, in the area under pulsed, non-supervised control actions operating under the guidelines of the National Vector Control Program (NCVP) than in the area under sustained, supervised surveillance carried out jointly by the UBA research team and NCVP. The prevalence of infestation and infection varied widely among village groups within each area. In the pulsed control area, the prevalence of infection in bugs, dogs and cats was two- to three-fold higher than in the area under sustained surveillance, most of the infected animals qualified as autochthonous cases, and evidence of recent transmission was observed. Infection was highly aggregated at the household level and fell close to the 80/20 rule. Using multiple logistic regression analysis clustered by household, infection in dogs was associated positively and significantly with variables reflecting local exposure to infected T. infestans, thus demonstrating weak performance of the vector surveillance system. For high-risk areas in the Gran Chaco region, interruption of vector-mediated domestic transmission of T. cruzi requires residual insecticide spraying that is more intense, of a higher quality and sustained in time, combined with community participation and environmental management measures. PMID:17686448

CARDINAL, M.V.; LAURICELLA, M.A.; MARCET, P.L.; OROZCO, M.M.; KITRON, U.; GURTLER, R.E.

2009-01-01

156

Adoptive immunotherapy against allogeneic kidney grafts in dogs with stable hematopoietic trichimerism.  

PubMed

Dogs given nonmyeloablative conditioning and marrow grafts from 2 dog leukocyte antigen (DLA)-identical littermate donors developed stable trichimerism and stably accepted a subsequent kidney graft from one of the marrow donors without the need for immunosuppression. In this study, we used trichimeras to evaluate strategies for adoptive immunotherapy to solid tumors, using the kidney as a tumor surrogate. Three DLA-identical trichimeric recipients were established by simultaneously infusing marrow from 2 DLA-identical donor dogs into a DLA-identical recipient conditioned with 2 Gy of total body irradiation (TBI) and given a short course of postgraft immunosuppression. After stable hematopoietic engraftment was confirmed, a kidney was transplanted from 1 of the 2 marrow donors into each respective trichimeric recipient. Peripheral blood lymphocytes from each kidney donor were then used to sensitize the alternate marrow donor. The trichimeric recipients were given donor lymphocyte infusions (DLIs) from the sensitized dogs and monitored for chimerism, graft-versus-host disease (GVHD), and kidney rejection. After DLI, we observed both prompt rejection of the transplanted marrow and donor kidney and disappearance of corresponding hematopoietic chimerism. Presumably due to shared minor histocompatibility antigens, host chimerism also disappeared, and GVHD in skin, gut, and liver developed. The native kidneys, although exhibiting lymphocytic infiltration, remained functionally normal. This study demonstrates that under certain experimental conditions, the kidney--an organ ordinarily not involved in graft-versus-host reactions--can be targeted by sensitized donor lymphocytes. PMID:18940673

Graves, Scott S; Hogan, William J; Kuhr, Christian; Diaconescu, Razvan; Harkey, Michael; Sale, George E; Stone, Brad; Georges, George E; Storb, Rainer

2008-11-01

157

Intraarticular Dirofilaria immitis microfilariae in two dogs  

Microsoft Academic Search

Dirofilaria immitis microfilariae were found in the synovial fluid of two dogs. One dog had clinical and cytological evidence of polyarthritis at the time of presentation. The second dog presented with severe effusion in a single joint and was later diagnosed with synovial sarcoma of the affected joint. These patients were not protected with heartworm prophylaxis and lived in heartworm

Steven Hodges; Mark Rishniw

2008-01-01

158

Factors Influencing Odor Sensitivity in the Dog.  

National Technical Information Service (NTIS)

The report covers an investigation of the possible influence of adaptation on the ability of dogs and human subjects to detect alpha-ionone; the form of the concentration-response function for alpha-ionone in dogs; the time trained dogs required to reach ...

D. G. Moulton

1975-01-01

159

Cephalic index and perceived dog trainability  

Microsoft Academic Search

People rank breeds of dogs for trainability despite a lack of evidence of breed differences in underlying behaviour. Instead of using behavioural information, people may use dog morphology to determine the trainability of breeds. Dogs are categorized as dolichocephalic, mesocephalic, or brachycephalic based on cephalic index, a ratio between skull width and length. Dolichocephalic breeds are anatomically more specialized for

William S. Helton

2009-01-01

160

49 CFR 236.743 - Dog, swing.  

Code of Federal Regulations, 2010 CFR

...Transportation 4 2010-10-01 2010-10-01 false Dog, swing. 236.743 Section 236.743 Transportation...DEVICES, AND APPLIANCES Definitions § 236.743 Dog, swing. A locking dog mounted in such a manner that it is free to...

2010-10-01

161

Have Fun. Be Active with Your Dog!  

MedlinePLUS

... a plan with a neighbor to walk the dogs together. l Take a brisk walk to your local dog park. Be imaginative. Walks are great, but consider ... walks, bring water for both you and your dog. l In hot weather, go out in the ...

162

50 CFR 216.82 - Dogs prohibited.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Dogs prohibited. 216.82 Section 216...Pribilof Islands Administration § 216.82 Dogs prohibited. In order to prevent molestation of fur seal herds, the landing of any dogs at Pribilof Islands is prohibited....

2010-10-01

163

Dog Committee Meeting Minutes November 16th  

E-print Network

1 Dog Committee Meeting Minutes November 16th , 2013 Merrimack County 4-H Office Boscawen, NH After introductions Rhiannon thanked all for attending. 4-H Dog Events in New Hampshire Several canine events open to 4-H youth were discussed. They include: · 4-H "All About Dogs" Weekend o Held annually

New Hampshire, University of

164

50 CFR 216.82 - Dogs prohibited.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Dogs prohibited. 216.82 Section 216...Pribilof Islands Administration § 216.82 Dogs prohibited. In order to prevent molestation of fur seal herds, the landing of any dogs at Pribilof Islands is prohibited....

2012-10-01

165

49 CFR 236.743 - Dog, swing.  

Code of Federal Regulations, 2013 CFR

...Transportation 4 2013-10-01 2013-10-01 false Dog, swing. 236.743 Section 236.743 Transportation...DEVICES, AND APPLIANCES Definitions § 236.743 Dog, swing. A locking dog mounted in such a manner that it is free to...

2013-10-01

166

50 CFR 216.82 - Dogs prohibited.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Dogs prohibited. 216.82 Section 216...Pribilof Islands Administration § 216.82 Dogs prohibited. In order to prevent molestation of fur seal herds, the landing of any dogs at Pribilof Islands is prohibited....

2013-10-01

167

49 CFR 236.743 - Dog, swing.  

Code of Federal Regulations, 2011 CFR

...Transportation 4 2011-10-01 2011-10-01 false Dog, swing. 236.743 Section 236.743 Transportation...DEVICES, AND APPLIANCES Definitions § 236.743 Dog, swing. A locking dog mounted in such a manner that it is free to...

2011-10-01

168

50 CFR 216.82 - Dogs prohibited.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Dogs prohibited. 216.82 Section 216...Pribilof Islands Administration § 216.82 Dogs prohibited. In order to prevent molestation of fur seal herds, the landing of any dogs at Pribilof Islands is prohibited....

2011-10-01

169

49 CFR 236.743 - Dog, swing.  

Code of Federal Regulations, 2012 CFR

...Transportation 4 2012-10-01 2012-10-01 false Dog, swing. 236.743 Section 236.743 Transportation...DEVICES, AND APPLIANCES Definitions § 236.743 Dog, swing. A locking dog mounted in such a manner that it is free to...

2012-10-01

170

Dipylidium (Dog and Cat Flea Tapeworm) FAQs  

MedlinePLUS

... the most common kind of tapeworm dogs and cats get? The most common tapeworm of dogs and cats in the United States is called Dipylidium caninum . ... infected with a tapeworm larvae. A dog or cat may swallow a flea while self-grooming. Once ...

171

Barking in family dogs: An ethological approach  

Microsoft Academic Search

Although it is one of the most conspicuous features of dog behaviour, barking has received little attention from ethologists or from an applied perspective. In this review, an ethological look is taken at the communicative aspect of dog barking. Emerging new research has indicated that in the repertoire of dog vocalisations barking has unique features in showing wide ranges of

Péter Pongrácz; Csaba Molnár; Ádám Miklósi

2010-01-01

172

Dogs as pets, visitors, therapists and assistants.  

PubMed

Dogs can play an integral role in the recovery of patients through companionship, animal-assisted therapy, and as assistance dogs. This article will define and differentiate these 3 categories and provide resources for home healthcare and hospice clinicians who may want to include dogs in the plan of care for select patients. PMID:25370974

Winkle, Melissa Y; Wilder, Anna; Jackson, Liberty Z

2014-01-01

173

Paleoeskimo Dogs of the Eastern Arctic  

Microsoft Academic Search

Sled or pack dogs have been perceived as an integral part of traditional life in the Eastern Arctic. This perception stems from our knowledge of the lifeway of recent Thule and modern Inuit peoples, among whom dog sledding has often been an important means of transportation. In contrast, the archaeological record of preceding Paleoeskimo peoples indicates that dogs were sparse

DARCY F. MOREY; KIM AARIS-SŘRENSEN

2002-01-01

174

4-H Family Dog Score Sheet This class is designed for 4-H members enrolled in the Family Dog Project. While in the ring the dog will  

E-print Network

4-H Family Dog Score Sheet This class is designed for 4-H members enrolled in the Family Dog Project. While in the ring the dog will be on display and the member will demonstrate that the dog can sit, stay, come and walk calmly on a leash. The member should be able to discuss the dog's home care

New Hampshire, University of

175

Hyperthermia in running sled dogs.  

PubMed

Hyperthermia, as measured by increase in rectal temperature, was studied in a group of 22 adult mongrel sled dogs that had been selectively bred for high-speed (up to 33 km/h) races 16-50 km in distance. Under normal working conditions, rectal temperature in the sled dogs increased significantly during initial 15-20 min of run (gathered gallop) after which temperature usually stabilized or decreased slightly. Amount of increase in rectal temperature was correlated directly with ambient temperature but not with speed or distance. Significant differences in degree of hyperthermia were found among dogs but these differences were not correlated with such factors as sex, size, coat color, weight, or genetic history. Training was found to significantly diminish amount of increase in rectal temperature during work. Data from the present study were compared to those of other laboratory investigations and relationships of heat storage and radiative surface area to body weight are discussed. PMID:7263406

Phillips, C J; Coppinger, R P; Schimel, D S

1981-07-01

176

Extraskeletal osteosarcoma in two dogs.  

PubMed

Extraskeletal osteosarcoma (ESOS) of the spleen and jejunum was diagnosed in 2 dogs. As an extremely uncommon type of tumor that has proven difficult to treat, ESOS is associated with high rate of local recurrence and metastatic disease. Extraskeletal osteosarcoma principally affects older dogs, has no apparent breed predilection, and may develop more frequently in males. The cause of ESOS is unknown, but may involve malignant metaplasia of pluripotential mesenchymal cells into osteoblasts. Macroscopically, ESOS usually is observed as a hard mass and may appear similar to calcified hematoma or myositis ossificans. The classic radiographic appearance of ESOS is a soft tissue mass with focal mineralization and without adjacent bone involvement. PMID:2722641

Schena, C J; Stickle, R L; Dunstan, R W; Trapp, A L; Reimann, K A; White, J V; Killingsworth, C R; Hauptman, J G

1989-05-15

177

Cephalic index and perceived dog trainability.  

PubMed

People rank breeds of dogs for trainability despite a lack of evidence of breed differences in underlying behaviour. Instead of using behavioural information, people may use dog morphology to determine the trainability of breeds. Dogs are categorized as dolichocephalic, mesocephalic, or brachycephalic based on cephalic index, a ratio between skull width and length. Dolichocephalic breeds are anatomically more specialized for running and brachycephalic breeds are more specialized for fighting. Dog breeds rated as highly trainable are instead mesocephalic, morphological generalists. Looking trainable in dogs may reflect differences in physical morphology. PMID:19683035

Helton, William S

2009-11-01

178

Breed-specific dog-dandruff allergens.  

PubMed

Fifty-one patients with clinical history of dog allergy were skin prick tested with eight individual standardized dog breed-allergen preparations, one mixed breed-allergen preparation (Poodle/Alsatian), dog-serum albumin, and histamine hydrochloride, 1 mg/ml. All extracts were characterized by crossed immunoelectrophoresis and crossed radioimmunoelectrophoresis with a pool of sera from patients clinically sensitive to dog. The dog-breed extracts contained common antigens/allergens, as well as components represented only in one or two dog-breed extracts. The concentration corresponding 1000 BU/ml varied from 16 to 100 micrograms of protein per milliliter. The sensitivity of skin prick test was 67% to 88% for the various dog breed-allergen preparations, but only 18% for dog-serum albumin. Significant difference between the skin test response to different dog breed-allergen preparations indicating dog breed-specific allergens was obtained in 15% of the patients. There was no significant correlation between skin prick test results and symptoms related to a specific dog breed. PMID:2457041

Lindgren, S; Belin, L; Dreborg, S; Einarsson, R; Pĺhlman, I

1988-08-01

179

Handler beliefs affect scent detection dog outcomes.  

PubMed

Our aim was to evaluate how human beliefs affect working dog outcomes in an applied environment. We asked whether beliefs of scent detection dog handlers affect team performance and evaluated relative importance of human versus dog influences on handlers' beliefs. Eighteen drug and/or explosive detection dog/handler teams each completed two sets of four brief search scenarios (conditions). Handlers were falsely told that two conditions contained a paper marking scent location (human influence). Two conditions contained decoy scents (food/toy) to encourage dog interest in a false location (dog influence). Conditions were (1) control; (2) paper marker; (3) decoy scent; and (4) paper marker at decoy scent. No conditions contained drug or explosive scent; any alerting response was incorrect. A repeated measures analysis of variance was used with search condition as the independent variable and number of alerts as the dependent variable. Additional nonparametric tests compared human and dog influence. There were 225 incorrect responses, with no differences in mean responses across conditions. Response patterns differed by condition. There were more correct (no alert responses) searches in conditions without markers. Within marked conditions, handlers reported that dogs alerted more at marked locations than other locations. Handlers' beliefs that scent was present potentiated handler identification of detection dog alerts. Human more than dog influences affected alert locations. This confirms that handler beliefs affect outcomes of scent detection dog deployments. PMID:21225441

Lit, Lisa; Schweitzer, Julie B; Oberbauer, Anita M

2011-05-01

180

Sequence Diversities of Serine-Aspartate Repeat Genes among Staphylococcus aureus Isolates from Different Hosts Presumably by Horizontal Gene Transfer  

PubMed Central

Background Horizontal gene transfer (HGT) is recognized as one of the major forces for bacterial genome evolution. Many clinically important bacteria may acquire virulence factors and antibiotic resistance through HGT. The comparative genomic analysis has become an important tool for identifying HGT in emerging pathogens. In this study, the Serine-Aspartate Repeat (Sdr) family has been compared among different sources of Staphylococcus aureus (S. aureus) to discover sequence diversities within their genomes. Methodology/Principal Findings Four sdr genes were analyzed for 21 different S. aureus strains and 218 mastitis-associated S. aureus isolates from Canada. Comparative genomic analyses revealed that S. aureus strains from bovine mastitis (RF122 and mastitis isolates in this study), ovine mastitis (ED133), pig (ST398), chicken (ED98), and human methicillin-resistant S. aureus (MRSA) (TCH130, MRSA252, Mu3, Mu50, N315, 04-02981, JH1 and JH9) were highly associated with one another, presumably due to HGT. In addition, several types of insertion and deletion were found in sdr genes of many isolates. A new insertion sequence was found in mastitis isolates, which was presumably responsible for the HGT of sdrC gene among different strains. Moreover, the sdr genes could be used to type S. aureus. Regional difference of sdr genes distribution was also indicated among the tested S. aureus isolates. Finally, certain associations were found between sdr genes and subclinical or clinical mastitis isolates. Conclusions Certain sdr gene sequences were shared in S. aureus strains and isolates from different species presumably due to HGT. Our results also suggest that the distributional assay of virulence factors should detect the full sequences or full functional regions of these factors. The traditional assay using short conserved regions may not be accurate or credible. These findings have important implications with regard to animal husbandry practices that may inadvertently enhance the contact of human and animal bacterial pathogens. PMID:21625460

Xue, Huping; Lu, Hong; Zhao, Xin

2011-01-01

181

A retrospective study of 230 consecutive patients hospitalized for presumed travel-related illness (2000–2006)  

Microsoft Academic Search

A good knowledge of morbidity profiles among ill-returned travelers is necessary in order to guide their management. We reviewed\\u000a the medical charts of 230 patients hospitalized in one infectious diseases department in France for presumed travel-related\\u000a illnesses. The male-to-female ratio was 1.6 and the median age was 33 years (interquartile range [IQR], 25–50). Most patients\\u000a (70.9%) were returning from sub-Saharan Africa.

H. Leroy; C. Arvieux; J. Biziragusenyuka; J. M. Chapplain; C. Guiguen; C. Michelet; P. Tattevin

2008-01-01

182

Mitochondrial profiling of dog hairs  

Microsoft Academic Search

In order to make greater use of dog hairs as forensic evidence, we have developed a robust method for duplex amplification of adjacent 306 and 332bp amplicons within the 5? hypervariable region (5? HVR) of the canine mitochondrial control region. In support of this, a 595bp region covering 35 polymorphic sites has been sequenced from the blood of 105 UK

Jon H. Wetton; Jenny E. Higgs; Adrian C. Spriggs; Chris A. Roney; Carol S. F. Tsang; Aiden P. Foster

2003-01-01

183

Female African wild dogs emigrate  

Microsoft Academic Search

AMONG mammals, the common mechanism of individual transfer between social groups is male emigration. While studying the African wild dog (Lycaon pictus Temminck) over a period of 2 yr, we have recorded four positive cases of female group emigration, three possible cases of single female emigration, and only one possible case of male group emigration. From this we conclude that

Lory Herbison Frame; George W. Frame

1976-01-01

184

KEEPING OURSELVES SAFE NEAR DOGS  

E-print Network

a poster to help others understand and be aware of your `triggers', that is events or situations that might think may bite you? What if the situation were to change? Might your view be different? Discuss your, if a dog is likely to bite us in these situations? Look at these photographs carefully. Divide

Little, Tony

185

Aggressive conflicts amongst dogs and factors affecting them  

Microsoft Academic Search

Over one year, 206 dog owners were questioned in a veterinary clinic. The survey included two groups: 151 owners who visited the clinic because of an injury to their dog caused by another dog and 55 people who owned dogs that caused injuries to others. The questioning served to compare aggressors and victims of dog fights. The form contained 43

A. Roll; J. Unshelm

1997-01-01

186

)_ ^ ^^> ill / 5 4-H Dog Care and Training  

E-print Network

)_ ^ ^^> ill · / 5 4-H Dog Care and Training Leader Guide 4-H 120L Revised July 1985 Oregon State This publication is for 4-H dog club leaders to use in working more effectively with 4-H members in 4-H dog and understand animals. The dog project is an excellent tool for character development. Training a dog teaches

New Hampshire, University of

187

9 CFR 93.600 - Importation of dogs.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Importation of dogs. 93.600 Section 93.600 Animals and Animal...FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Dogs § 93.600 Importation of dogs. (a) All dogs. Dogs from any...

2013-01-01

188

9 CFR 93.600 - Importation of dogs.  

...2014-01-01 2014-01-01 false Importation of dogs. 93.600 Section 93.600 Animals and Animal...FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Dogs § 93.600 Importation of dogs. (a) All dogs. Dogs from any...

2014-01-01

189

Presuming the influence of the media: teenagers' constructions of gender identity through sexual/romantic relationships and alcohol consumption.  

PubMed

Using empirical data from group discussions and in-depth interviews with 13 to 15-year olds in Scotland, this study explores how teenagers' alcohol drinking and sexual/romantic relationships were shaped by their quest for appropriate gendered identities. In this, they acknowledged the influence of the media, but primarily in relation to others, not to themselves, thereby supporting Milkie's 'presumed media influence' theory. Media portrayals of romantic/sexual relationships appeared to influence teenagers' constructions of gender-appropriate sexual behaviour more than did media portrayals of drinking behaviour, perhaps because the teenagers had more firsthand experience of observing drinking than of observing sexual relationships. Presumed media influence may be less influential if one has experience of the behaviour portrayed. Drinking and sexual behaviour were highly interrelated: sexual negotiation and activities were reportedly often accompanied by drinking. For teenagers, being drunk or, importantly, pretending to be drunk, may be a useful way to try out what they perceived to be gender-appropriate identities. In sum, teenagers' drinking and sexual/romantic relationships are primary ways in which they do gender and the media's influence on their perceptions of appropriate gendered behaviour is mediated through peer relationships. PMID:24443822

Hartley, Jane E K; Wight, Daniel; Hunt, Kate

2014-06-01

190

[Lens luxation in dogs: a retrospective study of 134 dogs (2000-2011)].  

PubMed

This retrospective study evaluated cases of lens luxation in dogs that were documented at the University of Zurich Veterinary Teaching Hospital between 2000 and 2011. A total 134 dogs were included in the study. This population of dogs with lens luxation represents 0.41 % of all dogs presented to the Zurich Veterinary Teaching Hospital (32'523) and 3.02 % of all dogs presented to the ophthalmology service during the same time period. The 134 dogs represented over 40 different breeds, including mixed breeds. 63 of the dogs were male, 71 were female. The 134 dogs were divided in primary lens luxation (86 of the 134 dogs, 64 %) and secondary lens luxation (48 dogs, 36 %). The most frequent causes for secondary lens luxation were glaucoma (58 %), cataract (19 %) and trauma (17 %). This study shows the predisposition for primary lens luxations in terrier breeds, Chinese Crested dogs, Pinscher and Spitz. In contrast, Siberian Huskies, Basset Hounds, Bearded Collies, Cairn Terriers, mixed breed dogs, Bolonka Zwetna, Boston Terriers, Borzoi, Doberman, Eurasian, Leonberg, Luzerner Niederlaufhund and Weimaraner suffered significantly more often from secondary lens luxation. There was no sex predilection for primary or secondary lens luxation. Dogs with primary lens luxation were on average 7.39 ± 3.02 years old, which is significantly younger than the dogs with secondary lens luxation (9.12 ± 3.38 years). Dogs with primary lens luxation showed a significantly higher rate of a bilateral development than those with secondary lens luxation (85.5 % of the dogs with primary lens luxation and only 14.5 % of the dogs with secondary lens luxation showed it in both their eyes). PMID:24568806

Betschart; Hässig; Spiess

2014-03-01

191

WASHINGTON STATE 4-H DOG OBEDIENCE PROGRAM PRE-NOVICE SCORE SHEET  

E-print Network

.... Long Down (3 minutes) On Leash Down your dog Leave your dog Back to your dog Exercise finished Long Sit (1 minute) On Leash Sit your dog Leave your dog Back to your dog Exercise finished 30 Did not remain On Leash Leave your dog Call your dog Finish Exercise finished Extra command or signal to stay

New Hampshire, University of

192

WASHINGTON STATE 4-H DOG OBEDIENCE PROGRAM LONG SIT / LONG DOWN GROUP EXAMINATION CHART  

E-print Network

LONG DOWN Long Sit Sit your dog Leave your dog Back to your dog Exercise finished Long Down Down your dog Leave your dog Back to your dog Exercise finished A Did not remain in place B Went to another dogWASHINGTON STATE 4-H DOG OBEDIENCE PROGRAM LONG SIT / LONG DOWN GROUP EXAMINATION CHART SHOW

New Hampshire, University of

193

Going to the Dogs: The Dog and I, LLC  

ERIC Educational Resources Information Center

How do you go from being a successful mechanical engineer or the manager of an optical store to giving up the security of those positions and caring for man's best friend? Just ask the mother and daughter team of Diane Holstein and Lisa Ferrerio, co-owners of The Dog and I. Everyone has the dream of doing a job they love, but not everyone can make…

Carlson, Priscilla

2008-01-01

194

4-H Dog Fitting and Show Score Sheet Date _______________________ Class _________________  

E-print Network

4-H Dog Fitting and Show Score Sheet Date _______________________ Class _________________ Breed ______________________ Armband# ____________ Possible Points Points Earned Dog Condition and Appearance ____ Brushed without matting ____ Clean ears ____ Nails trimmed ____ Dog in good condition, not underweight 10 Handler

New Hampshire, University of

195

Purification and characterization of liver catalase in acatalasemic beagle dog: comparison with normal dog liver catalase  

Microsoft Academic Search

Catalase from acatalasemic dog liver was purified to homogeneity and its properties were compared with those of normal dog liver catalase. The purified acatalasemic and normal dog liver catalases were found to have the same molecular weight (230,000 Da) and isoelectric point (pI: 6.0–6.2) and both enzymes contained four hematins per molecule. The catalytic activity of catalase from acatalasemic dog

Kouichi Nakamura; Misa Watanabe; Yukio Sasaki; Toshihiko Ikeda

2000-01-01

196

Toxic smoke inhalation in fire victim dogs.  

PubMed

Fifteen dogs were found dead in a house that was on fire. Several of these dogs were partially burned. Four dogs were submitted for postmortem examination, 2 of which were determined to have died prior to the fire. Of the 2 submitted fire fatalities, only 1 dog had burns on its body (dorsum and right side of body). Internally, both dogs had soot deposits mixed with mucus in the larynx, trachea, and primary bronchi. Microscopically, soot was identified within both airways and alveolar spaces. There were no macroscopic or microscopic indications of vital heat exposure. High levels of carboxyhemoglobin were detected in the 2 dogs tested. The findings in this case support the use of postmortem examination and toxicology testing to allow for determination of vital reaction to heat and fire fumes. PMID:24442575

Stern, A W; Lewis, R J; Thompson, K S

2014-11-01

197

Dog handlers' and dogs' emotional and cortisol secretion responses associated with animal-assisted therapy sessions  

Microsoft Academic Search

The study investigated 13 dog handlers and 18 companion dogs (Canis familiaris) working as teams in nonhuman animal-assisted service. The handlers described in questionnaires what emotions they chose to associate with their daily life and therapeutic work. They described their emotional condition before and after therapeutic sessions, giving analogous descriptions for their dogs. Handlers collected saliva samples from themselves and

D. K. Haubenhofer; S. Kirchengast

2007-01-01

198

Incidence and impact of dog attacks on guide dogs in the UK  

Microsoft Academic Search

In a retrospective survey, researchers identified 100 incidents of attacks on guide dogs by other dogs. These were reviewed in order to determine the number, severity and impact on the handler and dog, and the characteristics of the aggressors and victims. During the study period there were more than three attacks reported each month, with 61 per cent of the

A. Brooks; R. Moxon; G. C. W. England

2010-01-01

199

"What Are All These Dogs Doing at School?" Using Therapy Dogs to Promote Children's Reading Practice  

ERIC Educational Resources Information Center

This article discusses how registered therapy dogs can motivate and support children as they practice reading aloud in the company of the dog and with the support of the dog's handler. It also offers practical advice to educators, librarians, administrators, and community members seeking to implement such a program in their communities.

Jalongo, Mary Renck

2005-01-01

200

Clostridium difficile in faeces from healthy dogs and dogs with diarrhea  

PubMed Central

Background This study was conducted to evaluate the faecal occurrence and characterization of Clostridium difficile in clinically healthy dogs (N?=?50) and in dogs with diarrhea (N?=?20) in the Stockholm-Uppsala region of Sweden. Findings Clostridium difficile was isolated from 2/50 healthy dogs and from 2/20 diarrheic dogs. Isolates from healthy dogs were negative for toxin A and B and for the tcdA and tcdB genes. Both isolates from diarrheic dogs were positive for toxin B and for the tcdA and tcdB genes. The C. difficile isolates from healthy dogs had PCR ribotype 009 (SE-type 6) and 010 (SE-type 3) whereas both isolates from dogs with diarrhoea had the toxigenic ribotype 014 (SE-type 21). One of the isolates from healthy dogs was initially resistant to metronidazole. Conclusions This study revealed presence of toxigenic C. difficile in faecal samples of diarrheic dogs and low number of non- toxigenic isolates in healthy dogs from Uppsala-Stockholm region in Sweden. However, more comprehensive studies are warranted to investigate the role of C. difficile in gastrointestinal disease in dogs. PMID:23497714

2013-01-01

201

Reproductive potential of Echinococcus multilocularis in experimentally infected foxes, dogs, raccoon dogs and cats  

Microsoft Academic Search

A total of 15 red foxes, 15 raccoon dogs, 15 domestic dogs and 15 domestic cats were each infected with 20,000 protoscolices of Echinococcus multilocularis. At 35, 63, and 90 days post inoculation (dpi), five animals from each group were necropsied and the worm burdens determined. The highest worm burdens in foxes (mean of 16,792) and raccoon dogs (mean of

C. M. O. Kapel; P. R. Torgerson; R. C. A. Thompson; P. Deplazes

2006-01-01

202

A study of dogs with kennel cough.  

PubMed

A detailed study of a population of dogs with kennel cough was undertaken. Twenty-seven (77 per cent) of a total of 35 dogs had pathological evidence of respiratory disease in the form of tracheobronchitis with, in some animals, exudative pneumonia. A variety of viral and bacterial agents were isolated from the respiratory tract of diseased dogs but Bordetella bronchiseptica and canine parainfluenza virus SV-5 appeared to be the most significant organisms recovered. PMID:207006

McCandlish, I A; Thompson, H; Cornwell, H J; Wright, N G

1978-04-01

203

[Dangerous dogs: application of federal regulations].  

PubMed

During the last years nearly in all provinces in Germany new, hotly debated rules were published in order to meet the threat dangerous dogs or so-called fighting dogs mean to animals and men. Comparing current regulations of different provinces two categories of rules can be identified: one considering particular breeds as extremely dangerous and the other defining and characterising the dangerous dog. The application of these regulations differs enormously in expenditure and procedure. Recent statistics of all registered dog-bites allow other conclusions than those which seemed to have been relevant for the elaboration of the existing legislation. This is particularly true for the breeds which are considered extremely dangerous. It seems to be more useful to use the expression dangerous dog in general. Routine application of the new regulations have, except from some cases, increased administrative input but have not improved the situation itself. Animals homes are complaining of more "fighting" dogs. The fact that it is extremely difficult to find a new owner for these dogs leads to additional animal health problems. Judgement and treatment of dogs presented to public authorities because of dog-biting has not become any easier and dogs causing severe injury are not even presented. The new regulations are not sufficiently preventive and do not really tackle the cause of the problem of dangerous dogs. The existing regulations were developed under a strong political pressure. Authorities are now calling into question the usefulness and purpose of the new legislation. In the past the problem of dangerous dogs was dealt with using general safety legislation and police regulations offering flexibility. Obviously there is an urgent need to identify countermeasures on a larger scale. PMID:10774066

Rossi-Broy, C

2000-03-01

204

Energy metabolism of Inuit sled dogs  

Microsoft Academic Search

We explored how seasonal changes in temperature, exercise and food supply affected energy metabolism and heart rate of Inuit\\u000a dogs in Greenland. Using open flow respirometry, doubly labeled water, and heart rate recording, we measured metabolic rates\\u000a of the same dogs at two different locations: at one location the dogs were fed with high energy food throughout the year while

Nadine Gerth; Paula Redman; John Speakman; Sue Jackson; J. Matthias Starck

2010-01-01

205

Degenerative lumbosacral stenosis in dogs.  

PubMed

Degenerative lumbosacral stenosis (DLSS) is the most common disorder of the caudal lumbar spine in dogs. This article reviews the management of this disorder and highlights the most important new findings of the last decade. Dogs with DLSS are typically neuro-orthopedic patients and can be presented with varying clinical signs, of which the most consistent is lumbosacral pain. Due to the availability of advanced imaging techniques such as computed tomography and magnetic resonance imaging that allow visualization of intervertebral disc degeneration, cauda equina compression, and nerve root entrapment, tailor-made treatments can be adopted for the individual patient. Current therapies include conservative treatment, decompressive surgery, and fixation-fusion of the L7-S1 junction. New insight into the biomechanics and pathobiology of DLSS and developments in minimally invasive surgical techniques will influence treatment options in the near future. PMID:20732601

Meij, Björn P; Bergknut, Niklas

2010-09-01

206

The Shadow of the Dog  

NSDL National Science Digital Library

This resource uses an everyday example of walking a dog as a context where students can observe changes in shadows over the course of a day, and deduce that light travels and tends to maintain its direction of motion. The activity is from PUMAS - Practical Uses of Math and Science - a collection of brief examples created by scientists and engineers showing how math and science topics taught in K-12 classes have real world applications.

207

Clifford the Big Red Dog  

NSDL National Science Digital Library

PBS Kids has companion sites for their programs that offer a number of activities for young users. This one features everyone's favorite enormous, bright-red pooch, Clifford. At Clifford's site, visitors can play a matching game, read a story, print a cut-out dog house, and print out pages to color. The site also offers some Clifford video clips. THe site is compact, easy to navigate, and well suited for their target audience.

2000-01-01

208

Super-Athletes ... sled dogs  

NSDL National Science Digital Library

Thirty-second monthly installment of our "What A Year!" website project, introducing life science breakthroughs to middle and high school students and their teachers. It would be impossible for a human to complete a 1,000-mile race, even if it were done in chunks, with plenty of recovery time. Unlike humans, sled dogs are able to maintain a high level of exercise for over two weeks without experiencing fatigue. Why is that?

2009-11-02

209

Ototoxicity in dogs and cats  

PubMed Central

Synopsis A variety of drugs in veterinary use have side effects that can potentially damage the senses of hearing or balance in animals. A large body of literature exists on the incidence and mechanisms of “ototoxicity” in experimental animals and in humans, but little is documented in domestic dogs and cats. However, the generality of these adverse actions across species allows us to extrapolate and provide the veterinarian with insight into possible complications of chemotherapy. PMID:23122180

Oishi, Naoki; Talaska, Andra E.; Schacht, Jochen

2012-01-01

210

Regulation of protein intake in adult dogs.  

PubMed

To determine whether adult dogs are able to regulate their intake of protein, 2-year-old female Beagles were allowed self-selection from 2 diets that differed in concentration of protein. Such a feeding regimen permitted the dogs to select for protein without affecting energy intake. Within the 1st week of the 4-week study, the dogs had established their pattern of protein intake. They selected approximately 30% of metabolizable energy from protein. Adult female rats offered the same diets also selected 30% of metabolizable energy from protein. The results indicated that adult dogs are able to regulate protein and energy intake. PMID:6822458

Romsos, D R; Ferguson, D

1983-01-01

211

Primary ciliary dyskinesia in Newfoundland dogs.  

PubMed

Primary ciliary dyskinesia was diagnosed in three Newfoundland dogs with histories of chronic rhinitis and bronchopneumonia from an early age. Thoracic radiographs of two of them showed severe, dependent bronchopneumonia and right displacement of the cardiac apex but normal positioning of other organs. Histopathological examination of sections of lung from the other dog showed severe bronchopneumonia. A semen sample from one dog had a high percentage of spermatozoa with abnormal tails and poor progressive motility. Transmission electron microscopy of nasal brushings from all three dogs showed consistent ultrastructural defects in the cilia, including an absence of outer and inner dynein arms, disorganisation of peripheral doublets, occasional supernumerary doublets and singlets, and consistently disorganised basal bodies and foot processes; sections of trachea from one dog also had disorganised basal bodies. Pedigree analysis was consistent with a monogenic autosomal recessive pattern of inheritance for the defect. One dog is still alive, one dog died aged five years two months, and one dog was euthanased aged nine months. This is the first time primary ciliary dyskinesia has been reported in Newfoundland dogs. PMID:10423815

Watson, P J; Herrtage, M E; Peacock, M A; Sargan, D R

1999-06-26

212

Diffuse Idiopathic Skeletal Hyperostosis in the dog.  

E-print Network

??Abstract Study design: A retrospective radiographic cohort study. Objective: To determine the prevalence of diffuse idiopathic skeletal hyperostosis (DISH) in a out-patient population of dogs… (more)

Kranenburg, Hendrik-jan

2008-01-01

213

Intrahost evolutionary dynamics of canine influenza virus in naive and partially immune dogs.  

PubMed

The patterns and dynamics of evolution in acutely infecting viruses within individual hosts are largely unknown. To this end, we investigated the intrahost variation of canine influenza virus (CIV) during the course of experimental infections in naďve and partially immune dogs and in naturally infected dogs. Tracing sequence diversity in the gene encoding domain 1 of the hemagglutinin (HA1) protein over the time course of infection provided information on the patterns and processes of intrahost viral evolution and revealed some of the effects of partial host immunity. Viral populations sampled on any given day were generally characterized by mean pairwise genetic diversities between 0.1 and 0.2% and by mutational spectra that changed considerably on different days. Some observed mutations may have affected antigenicity or host range, including reversions of CIV host-associated mutations. Patterns of sequence diversity differed between naďve and vaccinated dogs, with some presumably antigenic mutations transiently reaching high frequency in the latter. CIV populations are therefore characterized by the rapid generation and clearance of genetic diversity. Potentially advantageous mutations arise readily during the course of single infections and may give rise to antigenic escape or host range variants. PMID:20219907

Hoelzer, Karin; Murcia, Pablo R; Baillie, Gregory J; Wood, James L N; Metzger, Stephan M; Osterrieder, Nikolaus; Dubovi, Edward J; Holmes, Edward C; Parrish, Colin R

2010-05-01

214

Mixed-Breed Dogs Increasing in Popularity  

NSDL National Science Digital Library

To the average person words such as cockapoo, yorkipoo, and dorgi may seem inappropriate for polite conversation, but in actuality they are the names of mixed-breed dogs. Previously, many of these mixed-breed dogs (formerly referred to as mutts), would have been of little interest. But in recent years more and more people have become entranced with having these animals as household pets. The labradoodle, for example, was originally bred in Australia in the 1970s, and was used as a guide dog for allergy sufferers. These dogs are not at all cheap however, as some of these labradoodles can cost up to $4000. Another interesting development is that the labradoodle may become eligible for American Kennel Club recognition if there are at least 300 of them in at least 20 states with three substantiated generations of labradoodle to labradoodle mixing. Some dog experts are also touting the merits of these new mixes, claiming that the are in fact healthier than purebreds. Other experts in the field remain skeptical, such as Allan Reznik, editor-in-chief of Dog Fancy and Dog World magazines, who opined thusly: "It's indicative of a society that loves labels. Having a dog that is part spaniel and part poodle isn't enough -- it has to be a cockapoo."The first link leads to a news story from CNN.com that documents this latest trend in designer dogs, along with a nice table that deciphers what the names of these mixed-breeds mean exactly. The second link leads to another story about these new hybrid dogs from the National Geographic website, authored by Bijal P. Trivedi. The third link will take visitors to the homepage of the American Kennel Club, where they may read about various purebred dogs, browse a calendar of related events, and learn about the upcoming national dog championship event sponsored by the Club that will take place in Long Beach, California. The fourth link leads to a page devoted to the Schnoodle (a cross between a poodle and a schnauzer) provided by the Dog Breeder Info Center website. The fifth link leads to a site created by Catherine N. Ball (an adjunct professor of linguistics at Georgetown University) that offers a list of the words for the sounds that dogs make in several dozen languages, including Croatian, Esperanto, and Bengali. The final link leads to a fun site that allows visitors to engage in a virtual dog simulation game where they can prepare their animals to compete in the show ring.

215

Dog ownership, dog behaviour and transmission of Echinococcus spp. in the Alay Valley, southern Kyrgyzstan.  

PubMed

Echinococcosis is a re-emerging zoonotic disease in Kyrgyzstan, and the incidence of human infection has increased substantially since the collapse of the Soviet Union in 1991. Domestic dogs are hosts of Echinococcus spp. and play an important role in the transmission of these parasites. The demography, ecology and behaviour of dogs are therefore relevant in studying Echinococcus spp. transmission. Dog demographics, roles of dogs, dog movements and faecal environmental contamination were assessed in four rural communities in the Alay Valley, southern Kyrgyzstan. Arecoline purge data revealed for the first time that E. granulosus, E. canadensis and E. multilocularis were present in domestic dogs in the Alay Valley. Surveys revealed that many households had dogs and that dogs played various roles in the communities, as pets, guard dogs or sheep dogs. Almost all dogs were free to roam, and GPS data revealed that many moved outside their communities, thus being able to scavenge offal and consume rodents. Faecal environmental contamination was high, presenting a significant infection risk to the local communities. PMID:23985326

Van Kesteren, Freya; Mastin, Alexander; Mytynova, Bermet; Ziadinov, Iskender; Boufana, Belgees; Torgerson, Paul R; Rogan, Michael T; Craig, Philip S

2013-11-01

216

A survey of the dog population in rural Bangladesh.  

PubMed

Globally, Bangladesh ranks third in the number of human deaths from rabies. Although dogs are the principal known transmitters of rabies and knowledge of dog populations is essential for effective national control and proper planning, dog control programs are scarce in Bangladesh. Our objective was to count dogs in a rural area to understand the dog population of the country. For this purpose we selected six unions of Raipura upazila in Narsingdi district. Dog counting was done by direct observation following accepted guidelines. We determined the mean density of the dog population in Bangladesh to be 14 dog/km(2) (95% CI 3.7, 24) and the human:dog ratio to be 120 (95% CI 55, 184). Our paper contribute to the literature which shows great variation in the human:dog ratio across regions of the developing world. The human:dog ratio depends on the area's human (as well as dog) population, whereas dog density per unit area indicates the true number of dogs. We propose that extrapolating from the human:dog ratios of other regions not be relied upon for estimating dog populations, unless the ratios can be supplemented by actual counts of dogs within the target area. PMID:23590964

Hossain, Moazzem; Ahmed, Kamruddin; Marma, Aung Swi Prue; Hossain, Sohrab; Ali, Mohammad Azmat; Shamsuzzaman, Abul Khair Mohammad; Nishizono, Akira

2013-08-01

217

Pneumovirus in dogs with acute respiratory disease.  

PubMed

To determine which respiratory viruses circulate among confined dogs, we analyzed nasal and pharyngeal swab specimens from shelter dogs with acute respiratory disease. An unknown virus was isolated. Monoclonal antibody testing indicated that it was probably a pneumovirus. PCR and sequence analysis indicated that it was closely related to murine pneumovirus. PMID:20507755

Renshaw, Randall W; Zylich, Nancy C; Laverack, Melissa A; Glaser, Amy L; Dubovi, Edward J

2010-06-01

218

Prevalence of dental disorders in pet dogs  

Microsoft Academic Search

Oral disorders of the dog represent for veterinarians a medical challenge and an important field of interest from the economical point of view. Although many epidemiological studies on dental diseases in beagles bred under controlled conditions have been realized, information on frequency of these alterations in populations of pet dogs, especially in Central Europe, is far from complete. The aim

M. Kyllar; K. Witter

219

POLLUTION DETECTION DOGS: PROOF OF CONCEPT  

EPA Science Inventory

Dogs have been used extensively in law enforcement and military applications to detect narcotics and explosives for over thirty years. Dogs are regularly used in arson investigations to detect accelerants since they are much more accurate at discriminating between accelerants an...

220

The Sense of Smell in Dogs  

Microsoft Academic Search

IT is, I think, of some interest to supplement the very striking and exact experiments of Mr. Romanes on the scent of dogs, by an account of some experiments of a like kind made with a very different kind of dog, viz. a pug bitch. She was taught to hunt for small pieces of dry biscuit in a good-sized dining-room.

W. J. Russell

1887-01-01

221

Utilization of police dogs: a Turkish perspective  

Microsoft Academic Search

Purpose – The use of canines in the gathering of evidence is a valuable tool for law enforcement to discover crime and criminals. Narcotics, explosives, cadaver detection, search and rescue, or patrol dogs are prevalently used by most police organizations for combatting crime. Police service dogs decrease the time required and increase success in crime detection. The purpose of this

S. Sebnem Ozcan; Hulki Akin; Hakan Bayram; Musa Bas; Ahmet Yildiz; Atalay Ozdemiroglu

2009-01-01

222

Histoplasmosis in a dog from New Brunswick  

PubMed Central

A young dog was presented with a history of chronic diarrhea, anorexia, and weight loss. Histoplasma capsulatum was suspected, based on cytologic examination of lymph node aspirates and peritoneal fluid, and confirmed by fungal culture. To our knowledge, this is the first case of histoplasmosis diagnosed in a dog in Atlantic Canada. PMID:17824159

Tyre, Erica; Eisenbart, David; Foley, Peter; Burton, Shelley

2007-01-01

223

Pavlov's Dog - Nobel Prize Educational Game  

NSDL National Science Digital Library

The Pavlov's Dog game and related reading are based on some of the scientific achievements of Ivan Pavlov, who was awarded the 1904 Nobel Prize in Physiology or Medicine. Even though the first image that comes to mind with Ivan Pavlov is his drooling dogs, he was awarded the Nobel Prize for his pioneering studies of how the digestive system works.

2009-01-01

224

Interactions of wolves and dogs in Minnesota  

USGS Publications Warehouse

This article reports on the nature and extent of wolf-dog interactions in Minnesota, based on investigations of complaints received by personnel of the federal government dealing with wolf-depredation control. Findings may indicate the wolf-dog interactions that can be expected in other recovery areas.

Fritts, S.H.; Paul, W.J.

1989-01-01

225

49 CFR 236.742 - Dog, locking.  

Code of Federal Regulations, 2010 CFR

...Transportation 4 2010-10-01 2010-10-01 false Dog, locking. 236.742 Section 236.742 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.742 Dog, locking. A steel block attached to a locking bar or...

2010-10-01

226

Genetic Structure of the Purebred Domestic Dog  

Microsoft Academic Search

We used molecular markers to study genetic relationships in a diverse collection of 85 domestic dog breeds. Differences among breeds accounted for ~30% of genetic variation. Microsatellite genotypes were used to correctly assign 99% of individual dogs to breeds. Phylogenetic analysis separated several breeds with ancient origins from the remaining breeds with modern European origins. We identified four genetic clusters,

Heidi G. Parker; Lisa V. Kim; Nathan B. Sutter; Scott Carlson; Travis D. Lorentzen; Tiffany B. Malek; Gary S. Johnson; Hawkins B. DeFrance; Elaine A. Ostrander; Leonid Kruglyak

2004-01-01

227

49 CFR 236.742 - Dog, locking.  

Code of Federal Regulations, 2013 CFR

...Transportation 4 2013-10-01 2013-10-01 false Dog, locking. 236.742 Section 236.742 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.742 Dog, locking. A steel block attached to a locking bar or...

2013-10-01

228

A Folk Tale of a Dog  

E-print Network

Folk Tale of a Dog Translation of title Description (to be used in archive entry) Tshe 'dzin tells a folktale in which a dog helps three girls escape from a demon. Genre or type (i.e. epic, song, ritual) Folktale Name of recorder (if...

Bkra shis bzang po

2009-11-17

229

49 CFR 236.742 - Dog, locking.  

Code of Federal Regulations, 2012 CFR

...Transportation 4 2012-10-01 2012-10-01 false Dog, locking. 236.742 Section 236.742 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.742 Dog, locking. A steel block attached to a locking bar or...

2012-10-01

230

49 CFR 236.742 - Dog, locking.  

Code of Federal Regulations, 2011 CFR

...Transportation 4 2011-10-01 2011-10-01 false Dog, locking. 236.742 Section 236.742 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.742 Dog, locking. A steel block attached to a locking bar or...

2011-10-01

231

Primary ciliary dyskinesia in Newfoundland dogs  

Microsoft Academic Search

Primary ciliary dyskinesia was diagnosed in three Newfoundland dogs with histories of chronic rhinitis and bronchopneumonia from an early age. Thoracic radiographs of two of them showed severe, dependent bronchopneumonia and right displacement of the cardiac apex but normal positioning of other organs. Histopathological examination of sections of lung from the other dog showed severe bronchopneumonia. A semen sample from

P. J. Watson; M. E. Herrtage; M. A. Peacock; D. R. Sargan

1999-01-01

232

Belgian dog mitochondrial DNA database for forensics  

Microsoft Academic Search

A Belgian population sample of 117 unrelated breed dogs and mongrels, was mitochondrial DNA profiled by sequencing the two hypervariable regions HV1 and HV2. The complete control region of each dog was amplified in a single PCR. The combination of eight sequencing reactions compiles the mtDNA profile, of which each position was covered at least twice. 48 haplotypes were identified,

Stijn Desmyter; Sylvie Comblez

2009-01-01

233

Context specificity of inhibitory control in dogs  

PubMed Central

Across three experiments, we explored whether a dog's capacity for inhibitory control is stable or variable across decision-making contexts. In the social task, dogs were first exposed to the reputations of a stingy experimenter that never shared food and a generous experimenter who always shared food. In subsequent test trials, dogs were required to avoid approaching the stingy experimenter when this individual offered (but withheld) a higher-value reward than the generous experimenter did. In the A-not-B task, dogs were required to inhibit searching for food in a previously rewarded location after witnessing the food being moved from this location to a novel hiding place. In the cylinder task, dogs were required to resist approaching visible food directly (because it was behind a transparent barrier), in favor of a detour reaching response. Overall, dogs exhibited inhibitory control in all three tasks. However, individual scores were not correlated between tasks, suggesting that context has a large effect on dogs' behavior. This result mirrors studies of humans, which have highlighted intra-individual variation in inhibitory control as a function of the decision-making context. Lastly, we observed a correlation between a subject's age and performance on the cylinder task, corroborating previous observations of age-related decline in dogs' executive function. PMID:23584618

MacLean, Evan L.; Hare, Brian A.

2014-01-01

234

Skeletal muscle fibre types in the dog.  

PubMed Central

Using a variety of histochemical methods we have investigated the mATPase reaction of skeletal muscle fibres in the dog. Types I, IIA, IIDog (peculiar to the dog) and IIC fibres were identified. The results reveal that the interpretation of the fibre type composition depends on the methods used. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 PMID:8226288

Latorre, R; Gil, F; Vazquez, J M; Moreno, F; Mascarello, F; Ramirez, G

1993-01-01

235

Hyperferritinemia in Dogs with Splenic Hemangiosarcoma  

PubMed Central

ABSTRACT Serum ferritin concentration increases in dogs in association with various diseases. In this study, we measured serum ferritin levels in dogs with splenic masses, using a sandwich ELISA assay. Eleven dogs with hemangiosarcoma (HSA), six with hematoma, 1 with hemangioma and 3 with lymphoma were enrolled. All dogs with HSA had serum ferritin concentrations above the normal limit (1,357 ng/ml, mean + 2× standard deviation of normal). Increased serum ferritin concentrations have also been observed in few cases of hematoma, hemangioma and lymphoma. Therefore, hyperferritinemia is not specific for splenic HSA, but may have clinical usefulness as a sensitive test for the disease. Further evaluation of serum ferritin concentrations in dogs with splenic HSA is needed. PMID:23803459

CHIKAZAWA, Seishiro; HORI, Yasutomo; HOSHI, Fumio; KANAI, Kazutaka; ITO, Naoyuki; HIGUCHI, Seiichi

2013-01-01

236

Functional MRI in Awake Unrestrained Dogs  

PubMed Central

Because of dogs' prolonged evolution with humans, many of the canine cognitive skills are thought to represent a selection of traits that make dogs particularly sensitive to human cues. But how does the dog mind actually work? To develop a methodology to answer this question, we trained two dogs to remain motionless for the duration required to collect quality fMRI images by using positive reinforcement without sedation or physical restraints. The task was designed to determine which brain circuits differentially respond to human hand signals denoting the presence or absence of a food reward. Head motion within trials was less than 1 mm. Consistent with prior reinforcement learning literature, we observed caudate activation in both dogs in response to the hand signal denoting reward versus no-reward. PMID:22606363

Berns, Gregory S.; Brooks, Andrew M.; Spivak, Mark

2012-01-01

237

Herb induced liver injury presumably caused by black cohosh: a survey of initially purported cases and herbal quality specifications.  

PubMed

Herb induced liver injury (HILI) is a particular challenge that also applies to purported cases presumably caused by black cohosh (BC), an herb commonly used to treat menopausal symptoms. We analyzed and reviewed all published case reports and spontaneous reports of initially alleged BC hepatotoxicity regarding quality of case details and causality assessments. Shortcomings of data quality were more evident in spontaneous reports of regulatory agencies compared to published case reports, but assessments with the scale of CIOMS (Council for the International Organizations of Sciences) or its updated version revealed lack of causality for BC in all cases. The applied causality methods are structured, quantitative, and liver specific with clear preference over an ad hoc causality method or the liver unspecific Naranjo scale. Reviewing the case data and the reports dealing with quality specifications of herbal BC products, there is general lack of analysis with respect to authentication of BC in the BC products used by the patients. However, in one single regulatory study, there was a problem of BC authentication in the analysed BC products, and other reports addressed the question of impurities and adulterants in a few BC products. It is concluded that the use of BC may not exert an overt hepatotoxicity risk, but quality problems in a few BC products were evident that require additional regulatory quality specifications. PMID:21677326

Teschke, Rolf; Schwarzenboeck, Alexander; Schmidt-Taenzer, Wolfgang; Wolff, Albrecht; Hennermann, Karl-Heinz

2011-01-01

238

Identification of telomerase in dog  

E-print Network

map and multiple cloning site. . . . . . Southern blot cTR probe preparation. Restriction digest of pUC 19 Pst I clones with Pst I . Amplification by PRC of cTR fragment from pUC 19 Pst I clones . . . Amplification by PCR of cTR from dog genomic... with Qiagen QIAprep Spin Miniprep Kit (Qiagen, ?27104). The isolated clone's DNA was screened by PCR and restriction digest with EcoRI for the presence of the cTR gene (see Fig. 5 and Fig. 6). Bi D ee Se uencin ABI PE-ABI?4303150. 30 pmoles of primer, 400...

Lyuksyutova, Anna

2013-02-22

239

Dogs as Sentinels for Human Lyme Borreliosis in The Netherlands  

Microsoft Academic Search

Serum samples from hunters (n 5 440), their hunting dogs (n 5 448), and hunters without dog ownership (n 5 53) were collected in The Netherlands at hunting dog trials and were tested for antibodies against Borrelia burgdorferi by a whole-cell enzyme-linked immunosorbent assay. Additionally, 75 healthy pet dogs were tested. The results of this study indicate that the seroprevalence

H. A. T. Goossens; A. E. van den Bogaard; M. K. E. Nohlmans

2001-01-01

240

4 CFR 25.12 - Dogs and other animals.  

Code of Federal Regulations, 2010 CFR

...Accounts 1 2010-01-01 2010-01-01 false Dogs and other animals. 25.12 Section 25.12...ACCOUNTABILITY OFFICE BUILDING AND ON ITS GROUNDS § 25.12 Dogs and other animals. Dogs and other animals, except seeing eye dogs or...

2010-01-01

241

36 CFR 504.10 - Dogs and other animals.  

Code of Federal Regulations, 2010 CFR

...Property 3 2010-07-01 2010-07-01 false Dogs and other animals. 504.10 Section 504.10...SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.10 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2010-07-01

242

31 CFR 91.11 - Dogs and other animals.  

Code of Federal Regulations, 2010 CFR

...Treasury 1 2010-07-01 2010-07-01 false Dogs and other animals. 91.11 Section 91.11...BUREAU OF THE MINT BUILDINGS AND GROUNDS § 91.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2010-07-01

243

36 CFR 520.11 - Dogs and other animals.  

Code of Federal Regulations, 2010 CFR

...Property 3 2010-07-01 2010-07-01 false Dogs and other animals. 520.11 Section 520.11...PARK OF THE SMITHSONIAN INSTITUTION § 520.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2010-07-01

244

4 CFR 25.12 - Dogs and other animals.  

Code of Federal Regulations, 2012 CFR

...Accounts 1 2012-01-01 2012-01-01 false Dogs and other animals. 25.12 Section 25.12...ACCOUNTABILITY OFFICE BUILDING AND ON ITS GROUNDS § 25.12 Dogs and other animals. Dogs and other animals, except seeing eye dogs or...

2012-01-01

245

36 CFR 520.11 - Dogs and other animals.  

Code of Federal Regulations, 2013 CFR

...Property 3 2013-07-01 2012-07-01 true Dogs and other animals. 520.11 Section 520.11...PARK OF THE SMITHSONIAN INSTITUTION § 520.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2013-07-01

246

36 CFR 520.11 - Dogs and other animals.  

Code of Federal Regulations, 2011 CFR

...Property 3 2011-07-01 2011-07-01 false Dogs and other animals. 520.11 Section 520.11...PARK OF THE SMITHSONIAN INSTITUTION § 520.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2011-07-01

247

36 CFR 504.10 - Dogs and other animals.  

Code of Federal Regulations, 2011 CFR

...Property 3 2011-07-01 2011-07-01 false Dogs and other animals. 504.10 Section 504.10...SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.10 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2011-07-01

248

31 CFR 91.11 - Dogs and other animals.  

Code of Federal Regulations, 2011 CFR

...Treasury 1 2011-07-01 2011-07-01 false Dogs and other animals. 91.11 Section 91.11...BUREAU OF THE MINT BUILDINGS AND GROUNDS § 91.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2011-07-01

249

36 CFR 504.10 - Dogs and other animals.  

Code of Federal Regulations, 2013 CFR

...Property 3 2013-07-01 2012-07-01 true Dogs and other animals. 504.10 Section 504.10...SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.10 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2013-07-01

250

36 CFR 504.10 - Dogs and other animals.  

...Property 3 2014-07-01 2014-07-01 false Dogs and other animals. 504.10 Section 504.10...SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.10 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2014-07-01

251

31 CFR 407.11 - Dogs and other animals.  

...Treasury 2 2014-07-01 2014-07-01 false Dogs and other animals. 407.11 Section 407.11...TREASURY BUILDING AND THE TREASURY ANNEX § 407.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2014-07-01

252

Fluffiness of dog Fluffiness of towel Inferring Analogous Attributes  

E-print Network

Fluffiness of dog Fluffiness of towel = ?? Inferring Analogous Attributes Chao-Yeh Chen and Kristen dogs A striped dog? Yes. + Prediction3 ?? = Inferred attribute21 Learned category-sensitive attributes Dog Equine Spotted BrownStriped + - + - + - + - No training examples ?? Attribute Category No training

Grauman, Kristen

253

36 CFR 504.10 - Dogs and other animals.  

Code of Federal Regulations, 2012 CFR

...Property 3 2012-07-01 2012-07-01 false Dogs and other animals. 504.10 Section 504.10...SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.10 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2012-07-01

254

31 CFR 91.11 - Dogs and other animals.  

Code of Federal Regulations, 2012 CFR

...Treasury 1 2012-07-01 2012-07-01 false Dogs and other animals. 91.11 Section 91.11...BUREAU OF THE MINT BUILDINGS AND GROUNDS § 91.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2012-07-01

255

31 CFR 91.11 - Dogs and other animals.  

Code of Federal Regulations, 2013 CFR

...Treasury 1 2013-07-01 2013-07-01 false Dogs and other animals. 91.11 Section 91.11...BUREAU OF THE MINT BUILDINGS AND GROUNDS § 91.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2013-07-01

256

Exploring Interspecies Sensemaking: Dog Tracking Semiotics and Multispecies Ethnography  

E-print Network

Exploring Interspecies Sensemaking: Dog Tracking Semiotics and Multispecies Ethnography *Department tracking practices reconfigure human-dog relationships changing both humans and dogs. We question the sensemaking mechanisms by which both humans and dogs engage in context- mediation. We show how an indexical

257

4 CFR 25.12 - Dogs and other animals.  

Code of Federal Regulations, 2011 CFR

...Accounts 1 2011-01-01 2011-01-01 false Dogs and other animals. 25.12 Section 25.12...ACCOUNTABILITY OFFICE BUILDING AND ON ITS GROUNDS § 25.12 Dogs and other animals. Dogs and other animals, except seeing eye dogs or...

2011-01-01

258

31 CFR 91.11 - Dogs and other animals.  

...Treasury 1 2014-07-01 2014-07-01 false Dogs and other animals. 91.11 Section 91.11...BUREAU OF THE MINT BUILDINGS AND GROUNDS § 91.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2014-07-01

259

36 CFR 520.11 - Dogs and other animals.  

Code of Federal Regulations, 2012 CFR

...Property 3 2012-07-01 2012-07-01 false Dogs and other animals. 520.11 Section 520.11...PARK OF THE SMITHSONIAN INSTITUTION § 520.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2012-07-01

260

4 CFR 25.12 - Dogs and other animals.  

...Accounts 1 2014-01-01 2013-01-01 true Dogs and other animals. 25.12 Section 25.12...ACCOUNTABILITY OFFICE BUILDING AND ON ITS GROUNDS § 25.12 Dogs and other animals. Dogs and other animals, except seeing eye dogs or...

2014-01-01

261

36 CFR 520.11 - Dogs and other animals.  

...Property 3 2014-07-01 2014-07-01 false Dogs and other animals. 520.11 Section 520.11...PARK OF THE SMITHSONIAN INSTITUTION § 520.11 Dogs and other animals. Dogs and other animals, except seeing-eye dogs,...

2014-07-01

262

4 CFR 25.12 - Dogs and other animals.  

Code of Federal Regulations, 2013 CFR

...Accounts 1 2013-01-01 2013-01-01 false Dogs and other animals. 25.12 Section 25.12...ACCOUNTABILITY OFFICE BUILDING AND ON ITS GROUNDS § 25.12 Dogs and other animals. Dogs and other animals, except seeing eye dogs or...

2013-01-01

263

A Simple Genetic Architecture Underlies Morphological Variation in Dogs  

E-print Network

of canine genetic variation by genotyping 915 dogs from 80 domestic dog breeds, 83 wild canids, and 10 outbred African shelter dogs across 60,968 single-nucleotide polymorphisms (SNPs). Coupling this genomicA Simple Genetic Architecture Underlies Morphological Variation in Dogs Adam R. Boyko1,2. , Pascale

Paris-Sud XI, Université de

264

Dogs acquire food preferences from interacting with recently fed conspecifics  

Microsoft Academic Search

Social transmission of food preferences has been documented in many species including humans, rodents, and birds. In the current experiment, 12 pairs of domestic dogs (Canis familiaris) were utilized. Within each pair, one dog (the demonstrator) was fed dry dog food flavored with either basil or thyme. The second dog (the observer) interacted with one demonstrator for 10min before being

Gwen Lupfer-Johnson; Julie Ross

2007-01-01

265

Coping with blindness: a survey of 50 blind dogs  

Microsoft Academic Search

A telephone survey of 50 owners of blind dogs was made in order to assess how well visually deprived dogs can cope within their environment. Ten of the 50 dogs surveyed died or were euthanased as a direct result of their blindness or ocular disease. Three owners were unable to come to terms with their pet's visual loss. Two dogs

Z Chester; WT Clark

1988-01-01

266

Fatal dog attacks in Canada, 1990-2007  

Microsoft Academic Search

In Canada, public debates on dog attacks are dominated by studies from the United States. An elec- tronic search of media reports in the Canadian Newsstand database, for the years 1990 to 2007, identified 28 fatali- ties from dog-bite injuries. Predominant factors in this case series were owned, known dogs; residential location; children's unsupervised access to area with dogs; and

Malathi Raghavan

267

Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.  

PubMed

This study was designed to examine haemodynamic and haematologic effects of the crown-of-thorns starfish venom (Acanthaster planci venom: APV) in dogs. Severe systemic hypotension, thrombocytopenia and leukopenia were induced by APV (1.0 mg protein/kg i.v.), followed by gradual return to the baseline level within 60 min. Hypotension was presumably caused by two factors: an early decrease in systemic vascular resistance and the large reduction in cardiac output due to reduced ventricular filling. Indomethacin, a cyclooxygenase inhibitor, remarkably suppressed systemic hypotension induced by APV. The peak reduction in systemic pressure was associated with concomitant rise of plasma 6-keto-PGF1 alpha, a major stable metabolite of prostacyclin. Thus, the hypotensive effect of APV may be caused primarily by prostacyclin and/or some vasodilating prostaglandins. In contrast, thrombocytopenia and leukopenia were not affected by cyclooxygenase inhibitor, 5-lipoxygenase inhibitor or platelet activating factor (PAF) receptor antagonist. When APV was administered repeatedly, tachyphylaxis was developed in haemodynamic effects, but not in haematologic effects. These findings suggest that APV-induced hypotensive effects may occur mainly through endogenous production of vasodilating prostaglandins including prostacyclin, although APV-induced thrombocytopenia and leukopenia may be caused by other mechanism(s) unrelated to arachidonate metabolites and/or PAF. PMID:7846692

Shiroma, N; Noguchi, K; Matsuzaki, T; Ojiri, Y; Hirayama, K; Sakanashi, M

1994-10-01

268

Phylogenetic distinctiveness of Middle Eastern and Southeast Asian village dog Y chromosomes illuminates dog origins.  

PubMed

Modern genetic samples are commonly used to trace dog origins, which entails untested assumptions that village dogs reflect indigenous ancestry or that breed origins can be reliably traced to particular regions. We used high-resolution Y chromosome markers (SNP and STR) and mitochondrial DNA to analyze 495 village dogs/dingoes from the Middle East and Southeast Asia, along with 138 dogs from >35 modern breeds to 1) assess genetic divergence between Middle Eastern and Southeast Asian village dogs and their phylogenetic affinities to Australian dingoes and gray wolves (Canis lupus) and 2) compare the genetic affinities of modern breeds to regional indigenous village dog populations. The Y chromosome markers indicated that village dogs in the two regions corresponded to reciprocally monophyletic clades, reflecting several to many thousand years divergence, predating the Neolithic ages, and indicating long-indigenous roots to those regions. As expected, breeds of the Middle East and East Asia clustered within the respective regional village dog clade. Australian dingoes also clustered in the Southeast Asian clade. However, the European and American breeds clustered almost entirely within the Southeast Asian clade, even sharing many haplotypes, suggesting a substantial and recent influence of East Asian dogs in the creation of European breeds. Comparison to 818 published breed dog Y STR haplotypes confirmed this conclusion and indicated that some African breeds reflect another distinct patrilineal origin. The lower-resolution mtDNA marker consistently supported Y-chromosome results. Both marker types confirmed previous findings of higher genetic diversity in dogs from Southeast Asia than the Middle East. Our findings demonstrate the importance of village dogs as windows into the past and provide a reference against which ancient DNA can be used to further elucidate origins and spread of the domestic dog. PMID:22194840

Brown, Sarah K; Pedersen, Niels C; Jafarishorijeh, Sardar; Bannasch, Danika L; Ahrens, Kristen D; Wu, Jui-Te; Okon, Michaella; Sacks, Benjamin N

2011-01-01

269

Ectoparasites of dogs and cats in Albania.  

PubMed

One hundred eighty-one dogs and 26 short-hair cats from suburban areas around Tirana, Albania were examined for ectoparasite infestation. The dogs were examined on several occasions from 2005 through 2009 representing three seasons: winter (December-February), spring (March-May), and summer (June-August); the cats were examined in late autumn (November). In addition, deep ear swab specimens of 30 dogs were examined for ear mites. The arthropod ectoparasite fauna of the dogs included two tick species (Rhipicephalus sanguineus and Ixodes ricinus), three mite species (Sarcoptes scabiei var. canis, Otodectes cynotis, and Demodex canis), three flea species (Ctenocephalides canis, Ctenocephalides felis, and Pulex irritans), and one louse species (Trichodectes canis). In the dogs, rates of infestation were 23.8% for R. sanguineus, 0.6% for I. ricinus, 4.4% for S. scabiei var. canis, 6.7% for O. cynotis, 0.6% for D. canis, 75.7% for C. canis, 5.0% for C. felis, 8.3% for P. irritans, and 6.6% for T. canis. Mixed infestation with two or three species of ectoparasites was recorded on 38.1% of the dogs. Fleas infested 75.7% dogs (geometric mean, 3.96; range, 1-80) and were observed in winter, spring, and summer with increasing prevalences of 64.3%, 75.9%, and 100%. Ticks parasitized 24.3% of the dogs (geometric mean, 0.41; range, 1-331). R. sanguineus ticks were recorded on 34.2% and 50% of the dogs examined in spring and summer, respectively, but were absent on the dogs during winter except for a single I. ricinus specimen observed. Prevalence of infestation with R. sanguineus, S. scabiei var. canis, C. felis, P. irritans, and T. canis did not differ between dogs < or = 6 months and dogs > 6 months of age; however, prevalence of infestation with C. canis was significantly (p < 0.01) higher in dogs > 6 months old. There was no difference between the sexes for the prevalences of infestation with those parasites. The examination of the cats revealed infestation with only one species of ectoparasite, C. felis (prevalence, 100%; geometric mean, 2.5; range, 1-9). PMID:19690887

Xhaxhiu, Dashamir; Kusi, Ilir; Rapti, Dhimiter; Visser, Martin; Knaus, Martin; Lindner, Thomas; Rehbein, Steffen

2009-11-01

270

Forestry, Wildlife and Fisheries Graduate SeminarForestry, Wildlife and Fisheries Graduate Seminar Hunting with DogsHunting with Dogs  

E-print Network

Seminar Hunting with DogsHunting with Dogs tradition or travestytradition or travesty Matthew McCollister OutlineOutline IntroductionIntroduction -- Description of hunting with dogsDescription of hunting with dogs Types of HuntingTypes of Hunting Breeds, PurposeBreeds, Purpose Why is this Controversial

Gray, Matthew

271

Quantum non-barking dogs  

NASA Astrophysics Data System (ADS)

Quantum weak measurements with states both pre- and post-selected offer a window into a hitherto neglected sector of quantum mechanics. A class of such systems involves time dependent evolution with transitions possible. In this paper we explore two very simple systems in this class. The first is a toy model representing the decay of an excited atom. The second is the tunneling of a particle through a barrier. The post-selection criteria are chosen as follows: at the final time, the atom remains in its initial excited state for the first example and the particle remains behind the barrier for the second. We then ask what weak values are predicted in the physical environment of the atom (to which no net energy has been transferred) and in the region beyond the barrier (to which the particle has not tunneled). Thus, just as the dog that didn't bark in Arthur Conan Doyle's story Silver Blaze gave Sherlock Holmes meaningful information about the dog's non-canine environment, here we probe whether the particle that has not decayed or has not tunneled can provide measurable information about physical changes in the environment. Previous work suggests that very large weak values might arise in these regions for long durations between pre- and post-selection times. Our calculations reveal some distinct differences between the two model systems.

Imari Walker, Sara; Davies, Paul C. W.; Samantray, Prasant; Aharonov, Yakir

2014-06-01

272

Lymphangiosarcoma of dogs: a review.  

PubMed

Lymphangiosarcoma in dogs, an extremely rare tumour with only 16 cases reported in the literature, is reviewed. Lymphangiosarcoma in humans, also very rare, and known in post-mastectomy, chronically-lymphoedematous patients as 'Stewart-Treves' syndrome, is briefly outlined, as well as the various other causes of lymphoedema, both primary and secondary, which usually precede malignancy. Comparisons between human and canine lymphoedema are made when such references were found. The genetic links to primary lymphoedema and the manifestation thereof in humans are mentioned. Lymphangiosarcoma in the majority of human and canine patients is an aggressively malignant tumour with few patients surviving despite various attempted treatments. The tumour most commonly arises in the subcutaneous tissues and rapidly invades underlying tissues and may spread widely internally via haematogenous and lymphatic routes, with frequent pleural and chest involvement. The tumour has been reported mostly in medium- to large-breed dogs, in slightly more males than females, and in an age-range of 8 weeks to 13 years, with more cases aged 5 years and older. Methods of diagnosis, with the variations encountered, including routine histopathology, immunohistochemistry, electron microscopy, tissue culture characteristics and endothelial expression of glycocongugates, are discussed. PMID:16300179

Williams, J H

2005-09-01

273

Factors associated with aggressive responses in pet dogs  

Microsoft Academic Search

This study used The Canine Behavioral Assessment and Research Questionnaire (C-BARQ) and regression models to explore the relative importance of dog and owner characteristics, living environment and owner–dog interaction to household dogs’ aggressiveness towards strangers, owners and other dogs. Exploratory factor analysis revealed 10 interpretable factors from the Chinese translation of C-BARQ: stranger-directed aggression, owner-directed aggression, dog-directed aggression, social fear,

Yuying Hsu; Liching Sun

2010-01-01

274

Experimental infection of dogs with Sarcocystis from wapiti.  

PubMed

Ten domestic dogs became infected with Sarcocystis when fed simple portions of heart, esophagus and diaphragm from a two-year-old female wapiti (Cervus canadensis). The prepatent period was 14 days in all exposed dogs; the patent period ranged from 8 to 20 days. Neither the 10 control dogs, nor two dogs fed sporocysts collected from the infected dogs passed sporocysts within the study period. Sporocysts averaged 16.5 by 11.1 micron in size. PMID:113562

Margolin, J H; Jolley, W R

1979-04-01

275

Circovirus in Tissues of Dogs with Vasculitis and Hemorrhage  

PubMed Central

We characterized the complete genome of a novel dog circovirus (DogCV) from the liver of a dog with severe hemorrhagic gastroenteritis, vasculitis, and granulomatous lymphadenitis. DogCV was detected by PCR in fecal samples from 19/168 (11.3%) dogs with diarrhea and 14/204 (6.9%) healthy dogs and in blood from 19/409 (3.3%) of dogs with thrombocytopenia and neutropenia, fever of unknown origin, or past tick bite. Co-infection with other canine pathogens was detected for 13/19 (68%) DogCV-positive dogs with diarrhea. DogCV capsid proteins from different dogs varied by up to 8%. In situ hybridization and transmission electron microscopy detected DogCV in the lymph nodes and spleens of 4 dogs with vascular compromise and histiocytic inflammation. The detection of a circovirus in tissues of dogs expands the known tropism of these viruses to a second mammalian host. Our results indicate that circovirus, alone or in co-infection with other pathogens, might contribute to illness and death in dogs. PMID:23628223

Li, Linlin; McGraw, Sabrina; Zhu, Kevin; Leutenegger, Christian M.; Marks, Stanley L.; Kubiski, Steven; Gaffney, Patricia; Dela Cruz Jr, Florante N.; Wang, Chunlin; Delwart, Eric

2013-01-01

276

Eye diseases in Siberian husky dogs.  

PubMed

A full ophthalmic examination was performed on 40 Siberian husky dogs using direct and indirect ophthalmoscopy, gonloscopy and nasolacrimal cannulation. Eight (20%) of the dogs were found to have distichia, 10 (25%) had excessive medial caruncular hairs, 8 (20%) had absence, displacement, or narrowing of the nasolacrimal puncta, 2 (5%) had bilateral corneal crystalline opacities, and 2 (5%) had unilateral areas of lateral corneal lipidosis. Fifty percent of the dogs had some abnormality of the iridocorneal (drainage) angle. However, in only one of these was the deformity severe enough to require glaucoma prophylaxis. An association between blue iris colour and malformation of the iridocorneal angle was noted. PMID:1883291

Stanley, R G; Blogg, J R

1991-05-01

277

Dog Experts' Brains Distinguish Socially Relevant Body Postures Similarly in Dogs and Humans  

PubMed Central

We read conspecifics' social cues effortlessly, but little is known about our abilities to understand social gestures of other species. To investigate the neural underpinnings of such skills, we used functional magnetic resonance imaging to study the brain activity of experts and non-experts of dog behavior while they observed humans or dogs either interacting with, or facing away from a conspecific. The posterior superior temporal sulcus (pSTS) of both subject groups dissociated humans facing toward each other from humans facing away, and in dog experts, a distinction also occurred for dogs facing toward vs. away in a bilateral area extending from the pSTS to the inferior temporo-occipital cortex: the dissociation of dog behavior was significantly stronger in expert than control group. Furthermore, the control group had stronger pSTS responses to humans than dogs facing toward a conspecific, whereas in dog experts, the responses were of similar magnitude. These findings suggest that dog experts' brains distinguish socially relevant body postures similarly in dogs and humans. PMID:22720054

Kujala, Miiamaaria V.; Kujala, Jan; Carlson, Synnove; Hari, Riitta

2012-01-01

278

Evaluation of the shock index in dogs presenting as emergencies  

PubMed Central

Objectives To 1) determine the normal range for Shock Index (SI) [defined as heart rate (HR)/systolic blood pressure (SBP)], in healthy dogs, and 2) compare SI in healthy dogs with dogs presenting to the emergency room (ER) deemed to be in or not in a state of shock. Design Prospective study. Animals 68 clinically normal dogs,,18 dogs that were presented to the ER deemed to be in shock and 19 dogs presenting to the ER not deemed to be in shock. Setting University teaching hospital. Interventions Peripheral or central venous blood sampling. Measurements and Main Results Heart rate and SBP were recorded on simulated presentation (healthy dogs), and emergency presentations for both dogs deemed to be in shock and dogs not deemed in shock. Dogs in shock had a median SI of 1.37 (0.87–3.13), which was significantly higher than both other groups; dogs not deemed in shock had median SI 0.73 (0.56–1.20), P<0.0001 and healthy dogs had median SI 0.78 (0.37–1.30) P<0.0001), respectively. Receiver operator characteristic curve analysis suggested a SI cut-off of 1.0, yielding an area under the receiver operator characteristic (AUROC) of 0.89 (Specificity (Sp) 89, Sensitivity (Sn) 90) when comparing dogs deemed in shock with healthy dogs, and 0.92 (Sp 95, Sn 89) when comparing dogs in shock with to dogs not deemed in shock. Conclusions The SI is an easy and non-invasive patient parameter that is higher in dogs that are deemed to be in shock than both healthy dogs and dogs presented as emergencies but not deemed to be in a state of shock. The measurement of SI may have some benefit in clinical assessment of emergency patients. PMID:23855723

Porter, Adam E.; Rozanski, Elizabeth A.; Sharp, Claire R.; Dixon, Kursten L.; Lyn Price, Lori; Shaw, Scott P.

2013-01-01

279

Analysis of neuroretinal rim distribution and vascular pattern in eyes with presumed large physiological cupping: a comparative study  

PubMed Central

Background To investigate possible differences in neuroretinal rim distribution, vascular pattern, and peripapillary region appearance between eyes with presumed large physiological optic disc cupping (pLPC) and eyes with minimal optic disc excavation. Methods We prospectively enrolled consecutive subjects with pLPC and individuals with minimal excavation (optic disc excavation within normal limits; control group). All eyes had normal visual fields and untreated intraocular pressure (IOP) <21 mmHg. Eyes with pLPC required vertical cup-to-disc ratio (VCDR) ?0.6 and ?30 months of follow-up with no evidence of glaucomatous neuropathy. For controls, VCDR was limited to ?0.5. We compared ocular signs and characteristics related to the neuroretinal rim distribution, vascular pattern, peripapillary region appearance and disc size between groups. Whenever both eyes were eligible, one was randomly selected for analysis. Results A total of 74 patients (mean age, 45.6?±?14.9 years) with pLPC and 45 controls (mean age, 44.8?±?11.6 years) were enrolled (p?=?0.76). Median disc size and VCDR was significantly larger in eyes with pLPC compared to controls (p?

2014-01-01

280

Dogs  

MedlinePLUS

... septicemic and pneumonic, cause more severe disease. More Ringworm ( Microsporum canis ) Ringworm is a condition caused by a fungus that ... hair, and nails of both people and animals. Ringworm is transmitted from animals to people through direct ...

281

Vulvar lipoleiomyoma in a dog.  

PubMed

A vulvar neoplasm from a 5-year-old female Siberian Husky dog was removed surgically and examined histologically. Macroscopically, the neoplasm was firm, white, and measured 6 x 4 x 3 cm. Microscopically, the neoplasm was expansile, nonencapsulated, and composed of lobules of mature adipocytes ad-mixed with streams and bundles of well-differentiated smooth muscle cells. Immunohistochemically, the neoplastic cells had strong diffuse cytoplasmic immunoreactivity for alpha-smooth muscle actin and desmin, and no immunoreactivity for cytokeratin or vimentin. On the basis of gross, histopathologic, and immunohistochemical findings, a diagnosis of lipoleiomyoma was made. This is, to the author's knowledge, the first report of canine vulvar lipoleiomyoma. PMID:15690962

Radi, Zaher A

2005-01-01

282

Disseminated pseudallescheriosis in a dog.  

PubMed

A case of disseminated pseudallescheriasis in a German Shepherd bitch is presented. Bones (ilium, a rib and phalanges), joints (elbow and acetabulum) and the surrounding tissues were the principal organs affected. In addition, Pseudallescheria boydii was isolated, in lower numbers, from the eye, kidney, lymph nodes draining the affected regions and urine. The dog was euthanized. P. boydii was identified by morphologic characteristics and molecular techniques (beta tubulin sequence). In addition, an ITS nucleotide sequence analysis showed that this strain differed from another isolate identified as Scedosporium apiospermum that had caused a disseminated infection in another German Shepherd. The importance of the molecular characterization of fungi belonging to the Pseudallescheria/Scedosporium complex, isolated from animals is stressed in light of the ongoing attempts to recharacterize these fungi. PMID:19886774

Elad, D; Perl, S; Yamin, G; Blum, S; David, D

2010-06-01

283

Pathology Case Study: Dog Bites  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology, which describes a 56-year-old male with a past medical history significant for lymphoma (in remission). The patient is a health care worker who presented to the emergency room because of a dog bite. Visitors are given a patient history and culture findings, including images. They are also given an opportunity to diagnose the patient before clicking on the "Final Diagnosis" section, which provides a discussion of the findings as well as references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in clinical microbiology.

Iscoll, Eileen; Lourduraj, Leena T.; Pasculle, A. W.

2008-11-17

284

Theileria annae in a young Swedish dog.  

PubMed

A severe regenerative anemia was detected in a 12-week-old mixed breed puppy in Sweden. A small protozoan parasite was observed in erythrocytes on a blood smear. It was initially suspected to be Babesia gibsoni based on its size and because B. gibsoni was previously recorded in Sweden. Surprisingly, specific polymerase chain reaction analysis identified the protozoan as Theileria annae. T. annae is endemic in Northwest Spain, is very uncommonly reported elsewhere and has never been recorded in Scandinavia. T. annae has been identified in dogs used for dog fighting, and it is thought to be transmitted by dog bites. This puppy was a mixed pit bull terrier. Pit bull terriers are sometimes used for dog fighting. T. annae has been reported to be transmitted vertically, and in light of the puppy's age, this transmission was suspected in the present case. PMID:23842507

Falkenö, Ulrika; Tasker, Séverine; Osterman-Lind, Eva; Tvedten, Harold W

2013-01-01

285

Dog DNA---A Recipe for Traits  

NSDL National Science Digital Library

Students will discover how DNA will "code" for traits by performing a lab activity where segments of paper DNA (genes) are picked at random, a list of traits is made, and a dog is drawn featuring its genetic traits.

Perrault, Tanya

2012-02-20

286

Heartworm in dogs in Canada in 1983.  

PubMed

In late December 1983, 2 800 veterinarians across Canada were sent a questionnaire in order to assess the status of heartworm disease in Canada in 1983 and 26% of them responded. Veterinarians reported that 59 504 dogs were blood-tested to check for microfilariae and 771 dogs (1.30% of those tested) were found with Dirofilaria immitis. Heartworm disease was diagnosed in all provinces except New Brunswick and Newfoundland but most (733) of the cases were in Ontario.Heartworm disease was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 31% of the cases were observed with clinical signs of heartworm disease and 64% had a history of not having left Canada. Southwestern Ontario continues to be the focus of the infection and most of the dogs there had not left the province previously. PMID:17422451

Slocombe, J O; McMillan, I

1984-09-01

287

Factors Involved in Search Dog Training  

E-print Network

Events of significant impact as recent as hurricane Ike yielded a consistent disturbing truth: we lack sufficient numbers of competent search dog [Canis familiaris] teams. This study was conceived to provide information in identifying factors...

Alexander, Michael B.

2010-07-14

288

Bifidobacterium animalis subsp. lactis strains isolated from dog faeces.  

PubMed

The aim of the study was to identify and characterize dog bifidobacterial isolates and compare them with commercial probiotic strains. Sixteen isolates of Bifidobacterium animalis ssp. lactis from dog faeces (German Shepherd Dog) were identified by subspecies-specific PCR, MALDI-TOF MS and sequencing. This study is the first describing B. animalis ssp. lactis occurring within the intestinal tract of dogs. Our dog isolates showed slightly different fingerprinting profiles obtained by RAPD-PCR and REP-PCR from those isolated from yogurt and type strains of B. animalis ssp. lactis. Both, dog and yogurt origin strains indicated survival in the simulated in vitro digestion assay and were resistant to low pH and bile salts. Moreover, strong auto-aggregation activity was observed only in dog origin B. animalis ssp. lactis strains. Dog strains showed good properties predicting their survival ability in GIT and could be tested as a potential new probiotics for dogs or other hosts. PMID:22749610

Bunešová, V?ra; Vlková, Eva; Rada, Vojt?ch; Ro?ková, Sárka; Svobodová, Ivona; Jebavý, Lukáš; Kme?, Vladimír

2012-12-01

289

Mucocutaneous plasmacytomas in dogs: 75 cases (1980-1987).  

PubMed

Mucocutaneous plasmacytomas were diagnosed in 75 dogs. Medical records and communication with owners and referring veterinarians provided information regarding location and description of the tumor, clinicopathologic data, treatment, and postoperative status of the dogs. Males and females were equally represented, and most dogs were aged adults (mean, 9.7 years). Tumors developed most commonly in the mouth, on the feet or trunk, and in the ears. Plasmacytomas were confined to the skin and mucosa in 70 dogs. Two dogs had disseminated lymphoid neoplasia, and 1 dog developed cutaneous plasmacytoma during clinical remission of lymphosarcoma. Two dogs had multiple myeloma, which was diagnosed concurrently or within a few weeks of diagnosis of the cutaneous tumor. Multiple plasmacytomas were found in 10 dogs but were not associated with clinical signs of generalized disease. Tumors did not recur after surgical excision. Clinicopathologic values, when determined, were normal in all dogs with localized plasmacytomas. PMID:2466821

Rakich, P M; Latimer, K S; Weiss, R; Steffens, W L

1989-03-15

290

Functioning unilateral adrenocortical carcinoma in a dog.  

PubMed

An 11-year-old, 24-kg, intact female Siberian husky dog in anestrus had a 2-month history of polyuria and polydipsia. The dog had signs of mineralocorticoid excess such as hypertension and hypokalemia refractory to potassium supplementation. Abdominal ultrasound revealed an irregular mass in the left adrenal gland. The ACTH stimulation test for aldosterone concentration did not reveal hyperaldosteronism. Unilateral adrenalectomy was performed and histopathology identified adrenal cortical carcinoma. All clinical signs of mineralocorticoid excess ceased after surgery. PMID:23204580

Gójska-Zygner, Olga; Lechowski, Roman; Zygner, Wojciech

2012-06-01

291

WILDLIFE RESPONSES TO PEDESTRIANS AND DOGS  

Microsoft Academic Search

ABSTRACT We measured the responses of two grassland passerines, one forest passerine, and one large mammal exposed to recreational treatments both on- and off-trail, including a pedestrian alone, a pedestrian accompanied by a dog-on-leash, and a dog alone. Responses measured included flush response (whether the animal flushed or not), flush distance (distance between disturbance and animal when flushed), distance of

Richard L. Knight

292

Imaging diagnosis--spinal cord chondrosarcoma associated with spirocercosis in a dog.  

PubMed

A 7-year-old neutered female Boerboel cross was examined for progressive left pelvic limb lameness. There was no left patellar reflex but the remaining pelvic limb reflexes were hyperreflexic. Radiographically, there was a poorly mineralized opacity occupying the intervertebral foramen at LA-L5. On computed tomography images there was a hyperattenuating intramedullary lesion at LA-L5 that continued caudally, lateralized to the left and became extramedullary, terminating at L5-L6. In addition, well marginated, hyperattenuating lesions were noted at two muscular sites. The dog underwent euthanasia and a caudal esophageal mass was found at post mortem examination. The tumors in the spinal cord, the esophagus, and the skeletal muscles were diagnosed histologically as low-grade chondrosarcoma undergoing endochondral ossification. Spirocerca lupi-induced esophageal chondrosarcoma was believed to be the primary site from which the other, presumably metastatic, lesions originated. PMID:21158232

Lindsay, Nicolette; Kirberger, Robert; Williams, Mark

2010-01-01

293

Lymphocytic-plasmacytic enteritis in 24 dogs.  

PubMed

Lymphocytic-plasmacytic enteritis (LPE) was diagnosed by intestinal biopsy in 24 dogs with chronic small intestinal diarrhea. Vomiting, weight loss, and reduced appetite were frequent. Breed predispositions were not documented, although four patients were German Shepherd dogs. Hypoproteinemia, hypoalbuminemia, and hypoglobulinemia were common and most likely a result of protein-losing enteropathy. Other biochemical abnormalities were uncommon. Intestinal malabsorption was common. Neutrophilia (sometimes with increased band neutrophils), monocytosis, lymphopenia, and eosinopenia were the most consistent hematologic abnormalities. The severity of the lymphocytic-plasmacytic infiltration was not significantly different (P greater than 0.05) between regions of small intestine. However, the severity of cellular infiltration often varied among different regions of small intestine in the same dog. Changes in villous architecture and lacteal dilation were common. Intestinal nematode infestation was diagnosed in five dogs, and pancreatic exocrine insufficiency was diagnosed in one dog. In the remaining 18 dogs, besides LPE, no other associated or concurrent intestinal disease was diagnosed. PMID:2342021

Jacobs, G; Collins-Kelly, L; Lappin, M; Tyler, D

1990-01-01

294

Genomic Analyses of Modern Dog Breeds  

PubMed Central

A rose may be a rose by any other name, but when you call a dog a poodle it becomes a very different animal than if you call it a bulldog. Both the poodle and the bulldog are examples of dog breeds of which there are >400 recognized world-wide. Breed creation has played a significant role in shaping the modern dog from the length of his leg to the cadence of his bark. The selection and line-breeding required to maintain a breed has also reshaped the genome of the dog resulting in a unique genetic pattern for each breed. The breed-based population structure combined with extensive morphologic variation and shared human environments have made the dog a popular model for mapping both simple and complex traits and diseases. In order to obtain the most benefit from the dog as a genetic system, it is necessary to understand the effect structured breeding has had on the genome of the species. That is best achieved by looking at genomic analyses of the breeds, their histories, and their relationships to each other. PMID:22231497

Parker, Heidi G.

2013-01-01

295

Suppression of fertility in adult dogs.  

PubMed

Unfortunately, the overpopulation of dogs is still a problem in the majority of countries and even though surgical methods of sterilization, the most traditional and commonly used technique, have been intensively performed, the impact on the dog population is negligible. The neutering of companion animals as ovariohysterectomy (spaying) or orchidectomy (castration) has its limitations because of the cost, the need of a surgical environment and the risk of surgical and/or anaesthetical complications (ACCD 2009). In fact, surgical castration has been banished in some northern European countries and has limited acceptance in other countries. In a survey performed in Sao Paulo, Brazil, 56.5% of the owners of adopted shelter dogs were against the surgical procedure for different reasons (Soto et al. 2005). Currently, the options for contraception, defined as suppression of fertility are based on hormonal treatment. The treatments can be divided into analogues of gonadotropin releasing hormone (GnRH), progestins and androgens. Other possibilities of contraception are via the immunological system with vaccinations against GnRH, the luteinizing hormone (LH) receptor and the zona pellucida proteins. Finally, there is also the intra-epididymal or intratesticular injection of sclerosing substances in dogs. Mechanical devices to disrupt fertility are not used anymore due to the side effects. Suppression of fertility in adult dogs will be reviewed in order of use and possible impact on the dog population. PMID:24947862

Maenhoudt, C; Santos, N R; Fontbonne, A

2014-06-01

296

First Case of Pulmonary Disease Caused by a Mycobacterium avium Complex Strain of Presumed Veterinary Origin in an Adult Human Patient  

PubMed Central

We report the first case of pulmonary disease caused by a strain of Mycobacterium avium complex of presumed veterinary origin in an elderly patient. All serial isolates were identified by multilocus sequence analysis based on rpoB, hsp65, and 16S rRNA fragments. Disease persisted despite macrolide-based combination antibiotic therapy. PMID:23554206

Kim, Su-Young; Shin, Sung Jae; Lee, Nam Yong

2013-01-01

297

Efficacy of Malarone(®) in Dogs Naturally Infected with Babesia gibsoni.  

PubMed

The efficacy of Malarone(®) alone and in combination with doxycycline (DOXY) against Babesia gibsoni infections was examined in 8 dogs. In all dogs except one treated with Malarone(®), parasitemia decreased, and anemia improved soon after initiation of treatment. However, 3 of 4 dogs treated with Malarone(®) relapsed, and relapse was inhibited in 2 of 4 dogs treated with Malarone(®) and DOXY. All relapsed dogs responded well to the second treatment, but 1 dog relapsed again and did not respond to the third treatment. Malarone(®) may be useful for acute stage of B. gibsoni infections, and at least second repeating treatment might be effective. PMID:24909969

Iguchi, Aiko; Shiranaga, Nobuyuki; Matsuu, Aya; Hikasa, Yoshiaki

2014-10-01

298

Dog Experts' Brains Distinguish Socially Relevant Body Postures Similarly in Dogs and Humans  

Microsoft Academic Search

We read conspecifics' social cues effortlessly, but little is known about our abilities to understand social gestures of other species. To investigate the neural underpinnings of such skills, we used functional magnetic resonance imaging to study the brain activity of experts and non-experts of dog behavior while they observed humans or dogs either interacting with, or facing away from a

Miiamaaria V. Kujala; Jan Kujala; Synnöve Carlson; Riitta Hari

2012-01-01

299

Human Perception of Fear in Dogs Varies According to Experience with Dogs  

PubMed Central

To investigate the role of experience in humans’ perception of emotion using canine visual signals, we asked adults with various levels of dog experience to interpret the emotions of dogs displayed in videos. The video stimuli had been pre-categorized by an expert panel of dog behavior professionals as showing examples of happy or fearful dog behavior. In a sample of 2,163 participants, the level of dog experience strongly predicted identification of fearful, but not of happy, emotional examples. The probability of selecting the “fearful” category to describe fearful examples increased with experience and ranged from.30 among those who had never lived with a dog to greater than.70 among dog professionals. In contrast, the probability of selecting the “happy” category to describe happy emotional examples varied little by experience, ranging from.90 to.93. In addition, the number of physical features of the dog that participants reported using for emotional interpretations increased with experience, and in particular, more-experienced respondents were more likely to attend to the ears. Lastly, more-experienced respondents provided lower difficulty and higher accuracy self-ratings than less-experienced respondents when interpreting both happy and fearful emotional examples. The human perception of emotion in other humans has previously been shown to be sensitive to individual differences in social experience, and the results of the current study extend the notion of experience-dependent processes from the intraspecific to the interspecific domain. PMID:23284765

Wan, Michele; Bolger, Niall; Champagne, Frances A.

2012-01-01

300

Who Let the Dog in? How to Incorporate a Dog into a Self-Contained Classroom  

ERIC Educational Resources Information Center

Described in this article are outcomes, procedures, and suggestions for incorporating a dog into a classroom for students with emotional or behavioral disorders. First, the outcomes for the inclusion of a dog are presented and are reported from an empirical study conducted by the author. Next, details are provided on how teachers would initially…

Anderson, Katherine L.

2007-01-01

301

Human perception of fear in dogs varies according to experience with dogs.  

PubMed

To investigate the role of experience in humans' perception of emotion using canine visual signals, we asked adults with various levels of dog experience to interpret the emotions of dogs displayed in videos. The video stimuli had been pre-categorized by an expert panel of dog behavior professionals as showing examples of happy or fearful dog behavior. In a sample of 2,163 participants, the level of dog experience strongly predicted identification of fearful, but not of happy, emotional examples. The probability of selecting the "fearful" category to describe fearful examples increased with experience and ranged from.30 among those who had never lived with a dog to greater than.70 among dog professionals. In contrast, the probability of selecting the "happy" category to describe happy emotional examples varied little by experience, ranging from.90 to.93. In addition, the number of physical features of the dog that participants reported using for emotional interpretations increased with experience, and in particular, more-experienced respondents were more likely to attend to the ears. Lastly, more-experienced respondents provided lower difficulty and higher accuracy self-ratings than less-experienced respondents when interpreting both happy and fearful emotional examples. The human perception of emotion in other humans has previously been shown to be sensitive to individual differences in social experience, and the results of the current study extend the notion of experience-dependent processes from the intraspecific to the interspecific domain. PMID:23284765

Wan, Michele; Bolger, Niall; Champagne, Frances A

2012-01-01

302

Immunotherapy with dog and cat allergen preparations in dog-sensitive and cat-sensitive asthmatics.  

PubMed

Standardized dog and cat allergen preparations with defined allergen composition were used for immunotherapy (IT) in dog-sensitive and/or cat-sensitive adult patients. Seventeen patients completed 1 year of IT. Eleven patients were treated with dog allergen, five with cat allergen, and one with both dog and cat allergen. The treatment was well tolerated, with increased subjective tolerance. After 3 months of IT there was a significant decrease in conjunctival (p less than .05) and skin sensitivity (p less than .05). Specific IgE decreased significantly within 1 year as assayed by RAST and IgE-crossed radioimmunoelectrophoresis. Specific IgG increased in all patients. The results indicate that IT with potent and standardized dog and cat allergens influence the sensitivity to these allergens. PMID:2705663

Bucur, J; Dreborg, S; Einarsson, R; Ljungstedt-Pĺhlman, I; Nilsson, J E; Persson, G

1989-04-01

303

Molecular Genetic Diversity of the Gyeongju Donggyeong Dog in Korea  

PubMed Central

ABSTRACT The present study was conducted to analyze the genetic characteristics of the Donggyeong dog and establish parentage conservation systems for it by using 10 microsatellite markers recommended by the International Society for Animal Genetics (ISAG). A total of 369 dogs from 12 dog breeds including the Donggyeong dog were genotyped using 10 microsatellite loci. The number of alleles per locus varied from 5 to 10 with a mean value of 7.6 in the Donggyeong dog. The observed heterozygosity and expected heterozygosity ranged from 0.4706 to 0.9020 (mean 0.7657) and from 0.4303 to 0.8394 (mean 0.7266), respectively. The total exclusion probability of 10 microsatellite loci was 0.99955. Of the 10 microsatellite markers, the AHT121, AHTh260 and CXX279 markers had relatively high PIC values (?0.7). This study found that there were specific alleles, 116 allele at AHT121 in the Donggyeong dog when compared with other dog breeds. Also, the results showed two (Korean native dogs and the foreign dog breeds) distinct clusters. The closest distance (0.1184) was observed between the Donggyeong dog and Jindo dog, and the longest distance (0.3435) was observed between the Donggyeong dog and Bulgae. The Korean native dog breeds have comparatively near genetic distances between each other. PMID:25030603

LEE, Eun-Woo; CHOI, Seong-Kyoon; CHO, Gil-Jae

2014-01-01

304

Morphometry of skin changes in Newfoundland dogs following coat clipping.  

PubMed

Dog breeds are unique in their coat conformation and quality. Newfoundland dogs have a long and fine hair coat, and clipping may induce changes in newly grown hair. This study examined structural changes in the skin of Newfoundland dogs following clipping. Dogs included in the study had visible coat changes following clipping that appeared as loss of gloss, increased scaling and textural changes. The control groups consisted of two groups of dogs that had never been clipped: Newfoundland dogs served as within-breed controls, and long-haired dogs of other breeds served as between-breed controls. All dogs were healthy with no history of dermatological problems. Two skin biopsies were taken from each dog and evaluated for predetermined parameters. A total of 41 samples were examined: 11 from clipped Newfoundland dogs, 16 from unclipped ones, and 14 from dogs of other breeds. By histopathology, the clipped dogs had a thicker cornified layer (P=0.006) and smaller sebocytes (P=0.022) than the unclipped ones. Newfoundlands had larger and more epitrichial sweat glands than other breeds (P=0.0002, P=0.036, respectively), and those were not affected by clipping. These results suggest that hyperkeratosis and decreased sebocyte size may explain the observed coat changes following clipping in Newfoundland dogs. PMID:23317660

Zur, Gila; Regal, Keren; Loeb, Emmanuel

2013-06-01

305

Dog bite injuries to the hand.  

PubMed

Dog bites to the hand and forearm are common. Although bites are usually minor, aggressive dogs may cause extensive bites developing to a public health problem. In a database review of dog bites to the hand applied to Emergency Department or to the Department of Hand Surgery in Malmö, Sweden 2008-2009, we found 81 cases [42 men and 39 women; median age 45 (range 2-88) years]. Three of 81 (4%) were children younger than 11 years. Six of the 81 (8%) patients included had bilateral injuries. Seventy-five patients were treated at the Department of Hand Surgery, where 31 of 75 (41%) were admitted to hospital in 181 days (median 4, range 1-20). The injuries included lacerations of the skin, muscle, and tendons as well as fractures, arterial and nerve injuries, and traumatic amputations of fingers. Some cases developed infections, necrosis of muscle and skin, arthritis, osteomyelitis, and even sepsis. A total of 96 operations were done for 51 patients (median 1, range 1-8) and the patients had 343 (median 2, range 0-22) outpatient visits. Almost half of the bites occurred when the patients was trying to separate two fighting dogs. The size of the lacerations increased with the size of the dog. Serious infections were found independently of size of dog. We suggest that education of owners and the public, reporting of all bites, and control of animals are some of the actions to reduce the number of attacks. At least one serious case could have been prevented if the dog had been put down after a previous serious attack. PMID:21504280

Nygaard, Marianne; Dahlin, Lars B

2011-04-01

306

Analysis of Pediatric Facial Dog Bites  

PubMed Central

The aim of this study was to characterize and report the epidemiological data regarding pediatric facial dog bites. For this study, a retrospective chart review was used. This study was performed at a large tertiary pediatric hospital. All children younger than 18 years who sought medical attention after a facial dog bite between January 1, 2003, and December 31, 2008, were included. Demographic and epidemiologic data were collected and analyzed. A total of 537 children were identified. The average age was 4.59?±?3.36 years, with a slight male preponderance (52.0%). The majority of dog bites occurred in children 5 years of age or younger (68.0%). Almost all (89.8%) of the dogs were known to the children. When circumstances surrounding the bite were documented, over half (53.2%) of the cases were provoked. The most common breeds were mixed breed (23.0%), Labrador retriever (13.7%), Rottweiler (4.9%), and German shepherd (4.4%). Inpatient treatment was required in 121 (22.5%) patients with an average length of stay of 2.96?±?2.77 days. Children 5 years or younger were more likely to be hospitalized than older children. Children 5 years old and younger are at high risk for being bitten in the face by a familiar dog and are more likely to require hospitalization than older children. Certain dog breeds are more likely to bite, and there is often a history of provocation. There is a tremendous financial and psychosocial burden associated with dog bites, and prevention strategies should focus on education with the aid of public policies and better documentation and reporting systems. PMID:24436765

Chen, Henry H.; Neumeier, Anna T.; Davies, Brett W.; Durairaj, Vikram D.

2013-01-01

307

Oxygen cost of breathing in dogs.  

PubMed

The O2 cost of breathing has been calculated in awake and anesthetized dogs breathing spontaneously. Respiratory variables were measured in tracheostomized dogs in the standing position, while supported in a canvas sling, at room temperatures between 20 and 23 degrees C. Minute ventilation ranged between 3 and 53 liters/min while VO2 ranged from 61 to 686 ml/min. VE, VO2 and f varied considerably from measurement to measurement even though body temperatures and experimental conditions changed very little. VO2 increased with VE: VO2 = 10.2 VE + 58.4 r = 0.94. A cubic polynomial equation was also calculated for these data: VO2 = 11.6 + 19.0 VE-0.42 (VE)2 + 0.0057 (VE)3. Awake dogs showed panting and considerable hyperventilation (PACO2 = 22.5 +/- SD of 4.5 mm Hg). Anesthetized dogs had lower average values of f, VE and VO2; while average PACO2 was 29.1 +/- 4.5 mm Hg. VO2 and VE measured when the dogs were anesthetized, paralyzed and artifically ventilated were related by this equation: VO2 = 5.9 VE + 87.5, r = 0.88. The O2 cost of breathing, calculated by subtracting the regression equation obtained while the dogs were under artificial respiration, from the cubic polynomial equation, increased with increasing VE in a curvilinear fashion. The values for O2 cost of breathing at high levels of ventilation were high because dogs' lungs are small. After correcting for lung size, values for O2 cost of breathing were similar to those in humans. PMID:635302

Romo-Salas, F; Aquin, L; Searles, J M; Banchero, N

1978-01-01

308

Preference for copying unambiguous demonstrations in dogs (Canis familiaris).  

PubMed

In an earlier study (P. Pongracz et al., 2001), it was shown that human demonstration significantly enhances the detouring ability of dogs (Canis familiaris) around a V-shaped fence. The authors investigated the effect of the direction of the demonstrated detour and the dogs' detouring experience. They found that dogs' trial-and-error experience influences strongly the direction of the dogs' detours later, even if the demonstrator showed detours along the opposite side of the fence. However, dogs' preferences based on their own experiences were changed when the dogs observed demonstrations only on 1 side of the fence. Dogs with no trial-and-error experience followed the direction of 1-sided demonstrations. The change from dogs' own directions to the demonstrated directions seems not to be due to simple facilitative effects of social experience; the similarity with the demonstrated action depends on complex interactions between individual experience and socially provided information. PMID:14498810

Pongrácz, Péter; Miklósi, Adám; Timár-Geng, Katalin; Csányi, Vilmos

2003-09-01

309

My Dog Has Cancer: What Do I Need to Know?  

MedlinePLUS

... Products Vaccines, Blood & Biologics Articulos en Espanol My Dog Has Cancer: What Do I Need to Know? ... to top FDA-Approved Drugs for Cancer in Dogs Troutman says that sponsors are continuing to develop ...

310

Five common toxins ingested by dogs and cats.  

PubMed

When a dog or cat ingests a common household toxin, rapid decontamination is critical. This article provides treatment recommendations for some of the most common toxicoses in dogs and cats, along with a summary table for quick reference. PMID:19140100

Luiz, Julie A; Heseltine, Johanna

2008-11-01

311

Bounding on Rough Terrain with the LittleDog Robot  

E-print Network

A motion planning algorithm is described for bounding over rough terrain with the LittleDog robot. Unlike walking gaits, bounding is highly dynamic and cannot be planned with quasi-steady approximations. LittleDog is modeled ...

Shkolnik, Alexander C.

312

WISE Discovers Hyperluminous Hot DOGs  

NASA Astrophysics Data System (ADS)

One of the primary science objectives for NASA's Wide-field Infrared Survey Explorer (WISE) is to find the most luminous galaxies in the Universe. We have used WISE photometry to select an extraordinary all-sky sample of galaxies, which are prominent at 12 microns (W3) or 22 microns (W4), but faint or undetected at 3.4 microns (W1) and 4.6 microns (W2). Follow-up observations reveal that most of these galaxies are at redshift > 1.5, that they are hyperluminous (> 10^13 Lsun; with ~10% exceeding 10^14 Lsun, comparable to the most luminous optical QSOs). The follow-up observations also show that they are at least twice as hot as other types of infrared luminous galaxies, so that they are hot dust-obscured-galaxies, or Hot DOGs. Their SEDs have a very high mid-IR to submillimeter luminosity ratio, which is quite different from any existing galaxy templates. They may represent a rare, new phase in the galaxy evolution, possibly hosting extremely powerful super massive black holes.

Eisenhardt, Peter R.; Wu, J.; WISE Team

2013-01-01

313

The role of police dogs as companions and working partners.  

PubMed

Written responses to a questionnaire by 255 officers who used canines in police work were assessed. Almost all officers frequently played with, talked to, petted, and brushed their dogs and believed the dogs benefitted their health and well-being. Officers whose dogs slept indoors, often in the same bedroom, generally said they loved their dogs and they described their dogs as calm rather than active, as indicated by a multiple correspondence analysis. These 96 officers more than the 154 officers whose dogs slept outdoors or in kennels also planned to remain in canine work. Although departments often assumed responsibility for purchasing the dogs, the more experienced officers usually were involved in the final selection of dogs (logistic regression: p < .0001). Compared with 94 officers not involved in selecting their dogs, 106 officers with a specific role in selecting their dogs planned to stay in canine work, as shown by a multiple correspondence analysis. They believed the dogs had saved their lives (p < .01). Over-all, officers reported spending 4.1 hr. on-duty and 2.9 hr. off-duty per week training their dogs, and also played with them for 6.5 hr. per week, assuring a regular pattern of exercise for the officers. Virtually all officers valued canine service and believed the dogs enhanced the department's effectiveness. This study showed that both close companionship with the dog and involvement in selecting the dog were associated both with satisfaction with the dog and with working as a canine officer. PMID:10778270

Hart, L A; Zasloff, R L; Bryson, S; Christensen, S L

2000-02-01

314

Serum butyrylcholinesterase activity in dogs with diabetes mellitus  

Microsoft Academic Search

Increased serum butyrylcholinesterase (BChE) activity is a feature of diabetes mellitus (DM) in humans and rats. The objective of this study was to evaluate serum BChE activity in diabetic dogs. The activity of the enzyme was assessed in three cohorts of animals: (1) dogs with naturally occurring DM (n=74); (2) clinically normal dogs (n=74); and (3) dogs with various other

A. Tvarijonaviciute; J. J. Ceron; M. Caldin

315

Dogs turn left to emotional stimuli.  

PubMed

During feeding behaviour, dogs were suddenly presented with 2D stimuli depicting the silhouette of a dog, a cat or a snake simultaneously into the left and right visual hemifields. A bias to turn the head towards the left rather than the right side was observed with the cat and snake stimulus but not with the dog stimulus. Latencies to react following stimulus presentation were lower for left than for right head turning, whereas times needed to resume feeding behaviour were higher after left rather than after right head turning. When stimuli were presented only to the left or right visual hemifields, dogs proved to be more responsive to left side presentation, irrespective of the type of stimulus. However, cat and snake stimuli produced shorter latencies to react and longer times to resume feeding following left rather than right monocular visual hemifield presentation. Results demonstrate striking lateralization in dogs, with the right side of the brain more responsive to threatening and alarming stimuli. Possible implications for animal welfare are discussed. PMID:20060016

Siniscalchi, Marcello; Sasso, Raffaella; Pepe, Anna Maria; Vallortigara, Giorgio; Quaranta, Angelo

2010-04-01

316

Oxytocin promotes social bonding in dogs.  

PubMed

Recent evidence suggests that enduring social bonds have fitness benefits. However, very little is known about the neural circuitry and neurochemistry underlying the formation and maintenance of stable social bonds outside reproductive contexts. Oxytocin (OT), a neuropeptide synthetized by the hypothalamus in mammals, regulates many complex forms of social behavior and cognition in both human and nonhuman animals. Animal research, however, has concentrated on monogamous mammals, and it remains unknown whether OT also modulates social bonds in nonreproductive contexts. In this study we provide behavioral evidence that exogenous OT promotes positive social behaviors in the domestic dog toward not only conspecifics but also human partners. Specifically, when sprayed with OT, dogs showed higher social orientation and affiliation toward their owners and higher affiliation and approach behaviors toward dog partners than when sprayed with placebo. Additionally, the exchange of socio-positive behaviors with dog partners triggered the release of endogenous OT, highlighting the involvement of OT in the development of social relationships in the domestic dog. These data provide new insight into the mechanisms that facilitate the maintenance of close social bonds beyond immediate reproductive interest or genetic ties and complement a growing body of evidence that identifies OT as one of the neurochemical foundations of sociality in mammalian species. PMID:24927552

Romero, Teresa; Nagasawa, Miho; Mogi, Kazutaka; Hasegawa, Toshikazu; Kikusui, Takefumi

2014-06-24

317

Heartworm in dogs in Canada in 1989.  

PubMed

In late November 1989, 1732 clinics and institutional veterinarians were sent a questionnaire to assess the status of Dirofilaria immitis, and 51.7% responded. Of 247,716 dogs tested, 394 had D. immitis microfilariae and 51 were amicrofilaremic for a total of 445 cases and heartworm prevalence of 0.17%. Most (408) of these dogs had no preventive medication and the prevalence among dogs tested and unprotected was 1.01%. That prevalence was considerably higher in endemic areas. Thirty-seven dogs with heartworm had preventive medication. Heartworm was most frequent in companion dogs over three years of age maintained outdoors in rural areas. About 75% of the cases had never left Canada, 26% had clinical signs and 125 were not treated.Heartworm was reported from British Columbia, Manitoba, Ontario, Quebec, Nova Scotia and Newfoundland, but 383 cases were in Ontario. South-western Ontario was the primary focus of infection. There were 33 cases in Quebec and 24 in Manitoba, mainly found in and around Metropolitan Montreal and Winnipeg respectively. PMID:17423627

Slocombe, J O

1990-07-01

318

[The nature of the dog--a contribution to the keeping and breeding of so-called fighting dogs].  

PubMed

The behavioural repertoire of dogs derives from that of the wolf. But there are distinct race-specific differences which go back to the man's breeding influence in the course of domestication to develop special qualities in dogs. Today, dog keeping no longer corresponds to these qualities of dogs in many ways. We refer to the problems resulting from this and man's responsibility for the establishment of a man-dog relationship that is functional and responds to the dog's character. The abuse of certain dog behaviour by man has to be pursued consistently. In the same way we must also take care of an unforced integration of dogs into our society. PMID:1889368

Loeffler, K; Eichelberg, H

1991-06-01

319

MRI of surgically created pulmonary artery narrowing in the dog  

Microsoft Academic Search

Narrowing of the pulmonary arteries was created surgically in twelve dogs. In six of the dogs the narrowing was central (main pulmonary artery), and in the remaining six the narrowing was located peripherally at the hilar level of the right pulmonary artery beyond the pericardial reflection. MRI and angiography were performed in all dogs. MRI clearly delineated the site of

R. J. Hernandez; A. P. Rocchini; E. L. Bove; T. L. Chenevert; B. Gubin

1989-01-01

320

Isolation and characterisation of dog uropathogenic Proteus mirabilis strains  

Microsoft Academic Search

Proteus mirabilis strains isolated from the urine of dogs with urinary tract infections, were characterised with respect to the production of haemolysin and fimbriae. In contrast to healthy dogs, P. mirabilis was also isolated in high numbers from the faeces of dogs suffering from recurrent urinary tract infections. Production of fimbriae was demonstrated by electron microscopy and the presence of

Wim Gaastra; Robert A. A. van Oosterom; Eef W. J. Pieters; Hans E. N. Bergmans; Linda van Dijk; A. Agnes; H. M. ter Huurne

1996-01-01

321

Prairie dog engineering indirectly affects beetle movement behavior  

Microsoft Academic Search

Previous studies have shown that landscape structure influences animal movement and population structure. In this study, we show an indirect interaction between beetles and prairie dogs due to prairie dog ecosystem engineering. Gunnison's prairie dog (Cynomys gunnisoni Hollister) towns have more bare ground and are structurally less complex than adjacent unmodified grasslands. This results in bare ground facilitating beetle movement.

R. K. Bangert; C. N. Slobodchikoff

2004-01-01

322

Investigation of antibodies to extractable nuclear antigens in dogs.  

PubMed

Determination of antibodies to specific nuclear antigens, termed extractable nuclear antigen (ENA), was investigated in healthy dogs and in dogs with autoimmune, inflammatory, and neoplastic diseases. Using a counterimmunoelectrophoresis method, the dogs' sera were tested for antibodies against the nuclear antigens single-stranded DNA, Sm, Ro, La, ribonucleoprotein, Scl, and proliferating cell nuclear antigen. Antibodies to the Ro antigen were found in 1 dog with discoid lupus erythematosus, in 1 dog with pemphigus erythematosus, and in 1 dog with facial pyoderma and chronic superficial keratitis. In 15 dogs, antibodies were detected to ENA, but the precipitin lines were too weak to identify the specific ENA. These antibodies were found in some dogs with systemic lupus erythematosus, discoid lupus erythematosus, pemphigus erythematosus, dermatomyositis, vitiligo, lymphoma; in the dog with facial pyoderma and chronic superficial keratitis; and in 1 healthy dog. The highest percentage of dogs with antibodies to ENA in a large series (greater than 8) of this study was in dogs with systemic lupus erythematosus (4 of 13; 31%). PMID:1626770

White, S D; Rosychuk, R A; Schur, P H

1992-06-01

323

Dog population management for the control of human echinococcosis.  

PubMed

Cystic and alveolar hydatid disease of humans caused by infection with Echinococcus granulosus or Echinococcus multilocularis are significant zoonoses in developing countries. For human infections, the main definitive host is the dog, and reduction in the population of unwanted dogs, together with anthelmintic treatment of wanted dogs, are recommended control procedures for these zoonoses. Both owned and unowned dogs have been shown to be a major source of Echinococcus spp. infection in developing countries. Unowned dogs are the most challenging category in dog population management for the control of major zoonotic diseases. Unowned dogs are those dogs that do not have an owner, and those dogs whose owner cannot readily be identified. Control of numbers of unowned dogs can be done in various ways if funds are available. Fertility control and humane euthanasia are likely to be the most effective procedures in developing countries. Fertility control requires significant funding, and where resources are scarce humane euthanasia may be the most effective option. Both procedures are ongoing events, with no predictable end point. This paper examines the sociology and technology for the population management of owned and unowned dogs, specifically for the reduction of human hydatid disease. Examples are given for developing and developed countries. Although a "One Health" approach is desirable, the technology for hydatid control is different from that for rabies, and FAO Animal Welfare recommendations for dog population management should be adjusted accordingly. PMID:25046696

Kachani, Malika; Heath, David

2014-11-01

324

A Prairie Dog Abatement Program in San Juan County, Utah  

Microsoft Academic Search

Four species of prairie dogs are native to the plains and plateaus of the western United States. The most abundant and widely distributed of these is the blacktailed prairie dog, (Cynomys ludovicianus). This species has been a frequent topic of discussion at previous Great Plains Wildlife Damage Control workshops. Black-tailed prairie dog ecology and management was the topic of a

Terry A. Messmer; Jim Keyes; Roy McDonald

1993-01-01

325

46 CFR 386.19 - Dogs and other animals.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Dogs and other animals. 386.19 Section...STATES MERCHANT MARINE ACADEMY § 386.19 Dogs and other animals. Persons are prohibited from bringing dogs and other animals on to the Academy...

2010-10-01

326

36 CFR 262.11 - Impounding of dogs.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Impounding of dogs. 262.11 Section 262.11 Parks, Forests, and...Impoundments and Removals § 262.11 Impounding of dogs. Any dog found running at large in a part of the National...

2010-07-01

327

50 CFR 28.43 - Destruction of dogs and cats.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Destruction of dogs and cats. 28.43 Section 28.43 Wildlife and... Impoundment Procedures § 28.43 Destruction of dogs and cats. Dogs and cats running at large on a national wildlife...

2010-10-01

328

Inheritance of coat colour in the field spaniel dog  

E-print Network

Note Inheritance of coat colour in the field spaniel dog R Robinson St Stephens Nursery, Stephens known as roan. dog genetics / coat colour / field spaniel / breed R�sum� - H�r�dit� de la couleur du for the heredity of coat colour in the dog (Little, 1957; Robinson, 1990), it has become apparent as work

Paris-Sud XI, Université de

329

36 CFR 262.11 - Impounding of dogs.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Impounding of dogs. 262.11 Section 262.11 Parks, Forests, and...Impoundments and Removals § 262.11 Impounding of dogs. Any dog found running at large in a part of the National...

2011-07-01

330

LATEX circa 2010 Teaching an Old Dog New Tricks  

E-print Network

LATEX circa 2010 Teaching an Old Dog New Tricks Mark Hickman Department of Mathematics & Statistics 2010 Teaching an Old Dog New Tricks Mark Hickman Department of Mathematics & Statistics UniversityTeX\\ {\\em c i r c a } 2010}\\\\[3mm] 2 Teaching an Old Dog New Tricks } 3 \\ author {Mark Hickman\\\\ 4

Hickman, Mark

331

36 CFR 262.11 - Impounding of dogs.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Impounding of dogs. 262.11 Section 262.11 Parks, Forests, and...Impoundments and Removals § 262.11 Impounding of dogs. Any dog found running at large in a part of the National...

2013-07-01

332

46 CFR 386.19 - Dogs and other animals.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Dogs and other animals. 386.19 Section...STATES MERCHANT MARINE ACADEMY § 386.19 Dogs and other animals. Persons are prohibited from bringing dogs and other animals on to the Academy...

2012-10-01

333

46 CFR 386.19 - Dogs and other animals.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Dogs and other animals. 386.19 Section...STATES MERCHANT MARINE ACADEMY § 386.19 Dogs and other animals. Persons are prohibited from bringing dogs and other animals on to the Academy...

2013-10-01

334

36 CFR 262.11 - Impounding of dogs.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Impounding of dogs. 262.11 Section 262.11 Parks, Forests, and...Impoundments and Removals § 262.11 Impounding of dogs. Any dog found running at large in a part of the National...

2012-07-01

335

Port-access mitral valve replacement in dogs  

Microsoft Academic Search

Objective: The objective was to assess mitral valve replacement in a minimally invasive fashion by means of port-access technology. Methods: Fifteen dogs, 28 ± 3 kg (mean ± standard deviation), were studied with the port-access mitral valve replacement system (Heartport, Inc., Redwood City, Calif.). Eleven dogs underwent acute studies and were sacrificed immediately after the procedure. Four dogs were allowed

Mario F. Pompili; John H. Stevens; Thoms A. Burdon; Lawrence C. Siegel; William S. Peters; Greg H. Ribakove; Bruce A. Reitz

1996-01-01

336

Original article Determination of selamectin in dog plasma by high  

E-print Network

Original article Determination of selamectin in dog plasma by high performance liquid of selamectin in dog plasma, using High-Per- formance Liquid Chromatography (HPLC) with fluorescence detection and its suitability was demonstrated by a pharmacokinetic study on a dog receiving the therapeutic dose

Paris-Sud XI, Université de

337

46 CFR 386.19 - Dogs and other animals.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Dogs and other animals. 386.19 Section...STATES MERCHANT MARINE ACADEMY § 386.19 Dogs and other animals. Persons are prohibited from bringing dogs and other animals on to the Academy...

2011-10-01

338

Original article Cytokeratin immunostaining in normal dog major  

E-print Network

Original article Cytokeratin immunostaining in normal dog major and minor salivary glands Mahmut for cytokeratins 5, 6, 8, 17 and 19 of dog submandibular, sublingual, parotid, palatine, tongue and zygomatic sali. Mucous cells were not stained in any of the glands. © Inra/Elsevier, Paris salivary gland / dog

Paris-Sud XI, Université de

339

Genetic Evidence for an East Asian Origin of Domestic Dogs  

Microsoft Academic Search

The origin of the domestic dog from wolves has been established, but the number of founding events, as well as where and when these occurred, is not known. To address these questions, we examined the mitochondrial DNA (mtDNA) sequence variation among 654 domestic dogs representing all major dog populations worldwide. Although our data indicate several maternal origins from wolf, >95%

Peter Savolainen; Ya-ping Zhang; Jing Luo; Joakim Lundeberg; Thomas Leitner

2002-01-01

340

The conservation role of captive African wild dogs (Lycaon pictus)  

E-print Network

The conservation role of captive African wild dogs (Lycaon pictus) M.A.J. Frantzen, J.W.H. Ferguson the long-term survival of the African wild dog (Lycaon pictus). To aid this, a studbook was assembled the largest existing regional population of captive African wild dogs. These populations were investigated

Altwegg, Res

341

Distribution and conservation of African wild dogs in Cameroon  

Microsoft Academic Search

The African wild dog (Lycaon pictus) has de- clined dramatically during the last century and has experienced a significant reduction in its range throughout sub-Saharan Africa. Very little is known about wild dogs in Central Af- rica, especially the population in northern Cameroon. Human and ecological factors lim- iting wild dogs in and around Faro National Park were investigated in

Thomas Breuer

342

Wild dogs, Lycaon pictus, are a social species, obligated  

E-print Network

conditions apply for the African wild dog, Lycaon pictus, and data on this species in Zimbabwe support ourWild dogs, Lycaon pictus, are a social species, obligated to breed in a group, in which only one extinctions?: The case of wild dogs Angulo et al. Angulo et al. Frontiers in Zoology 2013, 10:11 http

Courchamp, Franck

343

Dog paw preference shows lability and sex differences  

Microsoft Academic Search

Paw preferences in domestic dogs were studied using three different behavioural tests, recording frequency, duration and latency of paw use. No overall population tendency to right- or left-paw preference was seen on any of the tests, nor could a sub-population of handed dogs be detected. This failure to replicate previous reports that male dogs tend to use their left paws

Fay Poyser; Christine Caldwell; Matthew Cobb

2006-01-01

344

Washington State 4-H Dog Project Rally Obedience  

E-print Network

be a sense of teamwork between the dog and handler both during the numbered exercises and betweenWashington State 4-H Dog Project Rally Obedience #12;#12;Table of Contents Introduction ......................................................................................................................15 #12;Introduction Rally is a sport in which the dog and handler complete a course that has been

New Hampshire, University of

345

Thrombocytosis associated with a myeloproliferative disorder in a dog  

SciTech Connect

A dog with a myeloproliferative disorder and thrombocytosis had clinical signs that were consistent with a diagnosis of essential thrombocythemia. The dog was treated with aspirin, radioactive phosphorus, and melphalan. Eighteen months after referral, the disorder progressed to chronic granulocytic leukemia, and treatment was switched to hydroxyurea. Fourteen months later, the dog was euthanatized because of uncontrollable atrial fibrillation.

Degen, M.A.; Feldman, B.F.; Turrel, J.M.; Goding, B.; Kitchell, B.; Mandell, C.P. (Univ. of California, Davis (USA))

1989-05-15

346

A possible predisposition to dilated cardiomyopathy in Huntaway dogs  

Microsoft Academic Search

AIM: To compare the prevalence of dilated cardiomyopathy (DCM) in New Zealand Huntaway dogs with the prevalence of DCM in other breeds of dog.METHODS: The necropsy database at Massey University was used to identify cases of DCM diagnosed between January 1999 and March 2006. Dogs were considered to have DCM if echocardiographic, gross necropsy, or histological findings were consistent with

JS Munday; CB Dyer; AC Hartman; GMB Orbell

2006-01-01

347

How Dogs Know when Communication Is Intended for Them  

ERIC Educational Resources Information Center

Domestic dogs comprehend human gestural communication in a way that other animal species do not. But little is known about the specific cues they use to determine when human communication is intended for them. In a series of four studies, we confronted both adult dogs and young dog puppies with object choice tasks in which a human indicated one of…

Kaminski, Juliane; Schulz, Linda; Tomasello, Michael

2012-01-01

348

Concurrent diabetes mellitus and lymphoma in a German shepherd dog  

Microsoft Academic Search

Summary Concurrent disorders with diabetes mellitus is one of the most challenging subject. Our knowledge of the most common concurrent disorders in diabetic dogs may be useful in diagnosis of these disorders and better treatment of diabetic dogs. In this study diabetes mellitus was diagnosed in a 7-year-old male German shepherd dog, based on clinical and laboratory findings. Following the

Selk Ghaffari; O. Dezfoulian; M. Selk Ghaffari

349

Comparative aspects of diabetes mellitus in dogs and cats  

Microsoft Academic Search

Diabetes mellitus is a common disease in cats and dogs. Its incidence is increasing, possibly due to an increase in obesity in both species. Different types of diabetes have been identified in pet animals. The classification of diabetic dogs and cats is modeled after the human classification but especially in the diabetic dogs, many aspects are different. The diabetic cat,

M Hoenig

2002-01-01

350

Evidence of cardiac autonomic neuropathy in dogs with diabetes mellitus  

Microsoft Academic Search

The NeuroScope, a specific and sensitive indicator of cardiac vagal tone, was used to look for differences in autonomic tone between 25 dogs with naturally occurring diabetes mellitus and 23 healthy control dogs, to determine whether there was any correlation between the dogs' cardiac vagal tone, the duration of diabetes and the adequacy of glycaemic control. The cardiac index of

S. Kenefick; N. Parker; L. Slater; A. Boswood

2007-01-01

351

Clinical peripheral neuropathy associated with diabetes mellitus in 3 dogs  

Microsoft Academic Search

Clinical and electrodiagnostic findings in 3 spontaneously diabetic dogs with clinical peripheral neuropathy (PN) are reported. Clinical signs of a PN may develop in diabetic dogs with adequate glycemic control. In addition, laryngeal paralysis may develop in association with diabetes mellitus in dogs with clinical PN. Résumé — Neuropathie périphérique clinique associée au diabčte sucré chez 3 chiens. Les données

Megan J. Morgan; Charles H. Vite; Anant Radhakrishnan; Rebecka S. Hess

352

Fear of novel and startling stimuli in domestic dogs  

Microsoft Academic Search

Dog aggression to humans is a serious problem and it appears that fear-induced aggression in dogs is often implicated. Furthermore, it has been suggested that novel and startling stimuli may trigger fear-induced aggression. The aim of the present study was to study some possible behavioural and physiological measures of fear in the dog Canis familiaris in tests involving novel and

T King; P. H Hemsworth; G. J Coleman

2003-01-01

353

Explosives detection by sniffer dogs following strenuous physical activity  

Microsoft Academic Search

Reduced olfactory efficiency in sniffer dogs results mainly from overheating, and causes physiological and behavioural resources to be diverted from concentration on the assigned task and applied instead to methods of body cooling. Dogs do not possess sweat glands, and panting is the main means of cooling the body. Since a dog can either sniff or pant, but can never

Irit Gazit; Joseph Terkel

2003-01-01

354

O1 Dog Pack revising mental models creating mental models  

E-print Network

O1 Dog Pack revising mental models creating mental models A1 First sources Q1 Folk Psychology Wolf Inquiry Activity Module 1. Dogs & People Partnerships ANSWER QUESTIONS Distinguish between observation (fact) and inference (interpretation) when folk psychology influences our understanding of dog

Packard, Jane M.

355

Vitamin E and exertional rhabdomyolysis during endurance sled dog racing  

Microsoft Academic Search

Exertional rhabdomyolysis (ER) is common in sled dogs, animals with high energy expenditures that consume high fat (60% of ingested calories) diets. Associations between pre-race plasma [vitamin E] and total antioxidant status (TAS) and risk of developing ER were examined in dogs competing in the 1998 Iditarod race. Pre-race blood samples were collected from 750 dogs and a second sample

Richard J Piercy; Kenneth W Hinchcliff; Paul S Morley; Robert A DiSilvestro; Gregory A Reinhart; Stuart L Nelson; Karin E Schmidt; A. Morrie Craig

2001-01-01

356

50 CFR 36.36 - Sled dogs and household pets.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Sled dogs and household pets. 36.36...Other Refuge Uses § 36.36 Sled dogs and household pets. The general...not apply to household pets and sled, work, or pack dogs under the direct control...

2013-10-01

357

50 CFR 36.36 - Sled dogs and household pets.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Sled dogs and household pets. 36.36...Other Refuge Uses § 36.36 Sled dogs and household pets. The general...not apply to household pets and sled, work, or pack dogs under the direct control...

2011-10-01

358

50 CFR 36.36 - Sled dogs and household pets.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Sled dogs and household pets. 36.36...Other Refuge Uses § 36.36 Sled dogs and household pets. The general...not apply to household pets and sled, work, or pack dogs under the direct control...

2010-10-01

359

50 CFR 36.36 - Sled dogs and household pets.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Sled dogs and household pets. 36.36...Other Refuge Uses § 36.36 Sled dogs and household pets. The general...not apply to household pets and sled, work, or pack dogs under the direct control...

2012-10-01

360

50 CFR 28.43 - Destruction of dogs and cats.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Destruction of dogs and cats. 28.43 Section 28.43 Wildlife and Fisheries...Impoundment Procedures § 28.43 Destruction of dogs and cats. Dogs and cats running at large on a national wildlife refuge and...

2011-10-01

361

50 CFR 28.43 - Destruction of dogs and cats.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Destruction of dogs and cats. 28.43 Section 28.43 Wildlife and Fisheries...Impoundment Procedures § 28.43 Destruction of dogs and cats. Dogs and cats running at large on a national wildlife refuge and...

2013-10-01

362

50 CFR 28.43 - Destruction of dogs and cats.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Destruction of dogs and cats. 28.43 Section 28.43 Wildlife and Fisheries...Impoundment Procedures § 28.43 Destruction of dogs and cats. Dogs and cats running at large on a national wildlife refuge and...

2012-10-01

363

The role of mediastinal and multi-organ CT scans in staging presumable surgical candidates with non-small-cell lung cancer  

Microsoft Academic Search

In order to evaluate the role of CT scan and bone scan in staging patients with non-small-cell lung cancer presumably indicated\\u000a for surgery, 70 consecutive patients who underwent thoracotomy were reviewed. Most of them received mediastinal and multi-organ\\u000a (brain, liver and adrenal) CT scans and a bone scan. In the most recent 40 of the 70 patients, CT findings of

Hiroaki Osada; Yasuo Nakajima; Yasuhiko Taira; Kumio Yokote; Teruhiko Noguchi

1987-01-01

364

The authority of next-of-kin in explicit and presumed consent systems for deceased organ donation: an analysis of 54 nations  

PubMed Central

Background. The degree of involvement by the next-of-kin in deceased organ procurement worldwide is unclear. We investigated the next-of-kin’s authority in the procurement process in nations with either explicit or presumed consent. Methods. We collected data from 54 nations, 25 with presumed consent and 29 with explicit consent. We characterized the authority of the next-of-kin in the decision to donate deceased organs. Specifically, we examined whether the next-of-kin’s consent to procure organs was always required and whether the next-of-kin were able to veto procurement when the deceased had expressed a wish to donate. Results. The next-of-kin are involved in the organ procurement process in most nations regardless of the consent principle and whether the wishes of the deceased to be a donor were expressed or unknown. Nineteen of the 25 nations with presumed consent provide a method for individuals to express a wish to be a donor. However, health professionals in only four of these nations responded that they do not override a deceased’s expressed wish because of a family’s objection. Similarly, health professionals in only four of the 29 nations with explicit consent proceed with a deceased’s pre-existing wish to be a donor and do not require next-of-kin’s consent, but caveats still remain for when this is done. Conclusions. The next-of-kin have a considerable influence on the organ procurement process in both presumed and explicit consent nations. PMID:22121233

Rosenblum, Amanda M.; Horvat, Lucy D.; Siminoff, Laura A.; Prakash, Versha; Beitel, Janice

2012-01-01

365

How do guide dogs of blind owners and pet dogs of sighted owners ( Canis familiaris ) ask their owners for food?  

Microsoft Academic Search

Although there are some indications that dogs (Canis familiaris) use the eyes of humans as a cue during human–dog interactions, the exact conditions under which this holds true are unclear.\\u000a Analysing whether the interactive modalities of guide dogs and pet dogs differ when they interact with their blind, and sighted\\u000a owners, respectively, is one way to tackle this problem; more

Florence Gaunet

2008-01-01

366

DOG-SPOT database for comprehensive management of dog genetic research data  

PubMed Central

Research laboratories studying the genetics of companion animals have no database tools specifically designed to aid in the management of the many kinds of data that are generated, stored and analyzed. We have developed a relational database, "DOG-SPOT," to provide such a tool. Implemented in MS-Access, the database is easy to extend or customize to suit a lab's particular needs. With DOG-SPOT a lab can manage data relating to dogs, breeds, samples, biomaterials, phenotypes, owners, communications, amplicons, sequences, markers, genotypes and personnel. Such an integrated data structure helps ensure high quality data entry and makes it easy to track physical stocks of biomaterials and oligonucleotides. PMID:21159202

2010-01-01

367

Country Dog Gentlemen Travel to Extraordinary Worlds  

NSDL National Science Digital Library

This interactive gallery designed for children of all ages was produced by the Education Department of the San Francisco Museum of Modern Art (SFMOMA). In the interactive, the "Country Dog Gentlemen", characters first depicted in a 1972 painting of the same name by the late Bay Area artist Roy De Forest (1930-2007), lead explorations of paintings and sculpture by Frieda Kahlo, Jackson Pollack, and Sargent Johnson. Students can watch the dogs sniffing out the story of each work, or create their own art, in various activities inspired by the originals. For example, the activity based on Kahlo's portrait, Frieda and Diego Rivera, 1931, is to swap the clothing and pets in Kahlo's work. The questions the Country Dog Gentlemen ask about Sargent Johnson's sculpture Forever Free, 1933, could make a good Black History Month lesson.

368

Astaxanthin uptake in domestic dogs and cats  

PubMed Central

Background Research on the uptake and transport of astaxanthin is lacking in most species. We studied the uptake of astaxanthin by plasma, lipoproteins and leukocytes in domestic dogs and cats. Methods Mature female Beagle dogs (18 to 19 mo old; 11 to 14 kg BW) were dosed orally with 0, 0.1, 0.5, 2.5, 10 or 40 mg astaxanthin and blood taken at 0, 3, 6, 9, 12, 18 and 24 h post-administration (n = 8/treatment). Similarly, mature domestic short hair cats (12 mo old; 3 to 3.5 kg body weight) were fed a single dose of 0, 0.02, 0.08, 0.4, 2, 5, or 10 mg astaxanthin and blood taken (n = 8/treatment) at the same interval. Results Both dogs and cats showed similar biokinetic profiles. Maximal astaxanthin concentration in plasma was approximately 0.14 ?mol/L in both species, and was observed at 6 h post-dosing. The plasma astaxanthin elimination half-life was 9 to 18 h. Astaxanthin was still detectable by 24 h in both species. In a subsequent study, dogs and cats were fed similar doses of astaxanthin daily for 15 to 16 d and astaxanthin uptake by plasma, lipoproteins, and leukocytes studied. In both species, plasma astaxanthin concentrations generally continued to increase through d 15 or 16 of supplementation. The astaxanthin was mainly associated with high density lipoprotein (HDL). In blood leukocytes, approximately half of the total astaxanthin was found in the mitochondria, with significant amounts also associated with the microsomes and nuclei. Conclusion Dogs and cats absorb astaxanthin from the diet. In the blood, the astaxanthin is mainly associated with HDL, and is taken up by blood leukocytes, where it is distributed to all subcellular organelles. Certain aspects of the biokinetic uptake of astaxanthin in dogs and cats are similar to that in humans. PMID:20565958

2010-01-01

369

Profile of dog bite victims in Jos Plateau State, Nigeria: a review of dog bite records (2006-2008)  

PubMed Central

Introduction Dogs are the major reservoir of rabies virus in Nigeria; transmission to humans is via a bite by rabid dog. Between 2006 and 2008 National Veterinary Research Institute (NVRI) rabies laboratory reported increased numbers of rabies in dogs and human dog bites. The objective of the study was to use veterinary and health records to develop a profile of bite victims and recommend appropriate public health actions. Methods We used the dog brain specimen result register of Rabies Laboratory of NVRI, from “January, 2006” to “December, 2008” and traced dog bite cases. Structured questionnaires were administered to persons who reported dog bite incident and could be traced. We reviewed records from Evangelical Churches of West Africa (ECWA) clinic from “January, 2006” to “December, 2008” to collect detailed profiles of bite victims. Results Bite victims linked to positive dog samples were traced to “ECWA clinic” from “January, 2006” to “December, 2008”. Most bite victims were <16 years 141 (72.3%), male 128 (65.6%), and 48.2% had primary school education. Bites were unprovoked 184 (94.4%), mostly on arms. 54.4% victims received complete post exposure prophylaxis (PEP). Majority of the biting dogs were housed and unvaccinated. Conclusion This study provided important information on the profile of dog bite victims and highlights the need for a sustained awareness and education of children on the dangers of dog bite. It has shown lack of enforcement of regulations for licensing of dogs and rabies vaccination. PMID:25328631

Alabi, Olaniran; Nguku, Patrick; Chukwukere, Silvester; Gaddo, Ayika; Nsubuga, Peter; Umoh, Joliath

2014-01-01

370

Genome Sequencing Highlights the Dynamic Early History of Dogs  

PubMed Central

To identify genetic changes underlying dog domestication and reconstruct their early evolutionary history, we generated high-quality genome sequences from three gray wolves, one from each of the three putative centers of dog domestication, two basal dog lineages (Basenji and Dingo) and a golden jackal as an outgroup. Analysis of these sequences supports a demographic model in which dogs and wolves diverged through a dynamic process involving population bottlenecks in both lineages and post-divergence gene flow. In dogs, the domestication bottleneck involved at least a 16-fold reduction in population size, a much more severe bottleneck than estimated previously. A sharp bottleneck in wolves occurred soon after their divergence from dogs, implying that the pool of diversity from which dogs arose was substantially larger than represented by modern wolf populations. We narrow the plausible range for the date of initial dog domestication to an interval spanning 11–16 thousand years ago, predating the rise of agriculture. In light of this finding, we expand upon previous work regarding the increase in copy number of the amylase gene (AMY2B) in dogs, which is believed to have aided digestion of starch in agricultural refuse. We find standing variation for amylase copy number variation in wolves and little or no copy number increase in the Dingo and Husky lineages. In conjunction with the estimated timing of dog origins, these results provide additional support to archaeological finds, suggesting the earliest dogs arose alongside hunter-gathers rather than agriculturists. Regarding the geographic origin of dogs, we find that, surprisingly, none of the extant wolf lineages from putative domestication centers is more closely related to dogs, and, instead, the sampled wolves form a sister monophyletic clade. This result, in combination with dog-wolf admixture during the process of domestication, suggests that a re-evaluation of past hypotheses regarding dog origins is necessary. PMID:24453982

Freedman, Adam H.; Gronau, Ilan; Schweizer, Rena M.; Ortega-Del Vecchyo, Diego; Han, Eunjung; Silva, Pedro M.; Galaverni, Marco; Fan, Zhenxin; Marx, Peter; Lorente-Galdos, Belen; Beale, Holly; Ramirez, Oscar; Hormozdiari, Farhad; Alkan, Can; Vila, Carles; Squire, Kevin; Geffen, Eli; Kusak, Josip; Boyko, Adam R.; Parker, Heidi G.; Lee, Clarence; Tadigotla, Vasisht; Siepel, Adam; Bustamante, Carlos D.; Harkins, Timothy T.; Nelson, Stanley F.; Ostrander, Elaine A.; Marques-Bonet, Tomas; Wayne, Robert K.; Novembre, John

2014-01-01

371

An Old Dog and New Tricks  

NASA Technical Reports Server (NTRS)

As I approach my 55th birthday, the old adage 'you can't teach an old dog new tricks' keeps coming to mind. I'm not sure why, because I don't feel old and I'm still interested in taking on new challenges and learning new tricks. However, as I mentor new project managers, I am also aware that others may consider me an old dog unable to learn new tricks. To the contrary, the people I mentor continue to teach me new tricks and challenge my assumptions about project management.

Cameron, W. Scott

2003-01-01

372

Intranasal malignant melanoma in a dog.  

PubMed

A 10-year-old, female Newfoundland-cross dog was presented for evaluation of chronic intermittent unilateral epistaxis, nasal stertor, and sneezing. Nasal magnetic resonance imaging revealed a 3 x 5-cm mass in the left nasal cavity. Histopathological evaluation of nasal biopsies determined that the mass was a malignant melanoma. The mass was surgically resected and treated with bilateral opposed photon-beam radiation. This is the first report to describe the presentation, diagnosis, and treatment of an intranasal malignant melanoma in a dog. PMID:17088396

Hicks, Daniel G; Fidel, Janean L

2006-01-01

373

Pediatric seizure disorders in dogs and cats.  

PubMed

Seizure disorders in young animals pose different considerations as to cause and therapeutic decisions compared with adult animals. Infectious diseases of the nervous system are more likely in puppies and kittens compared with adults. The diagnosis of canine distemper is often based on clinical signs. Idiopathic epilepsy typically occurs in dogs between 1 and 5 years of age; however, inflammatory brain diseases such as necrotizing encephalitis and granulomatous meningoencephalomyelitis also commonly occur in young to middle-aged small-breed dogs. The choice of which anticonvulsant to administer for maintenance therapy is tailored to each individual patient. PMID:24580991

Lavely, James A

2014-03-01

374

Guidelines for vaccination of dogs and cats in Korea  

PubMed Central

This guideline contains the recommended vaccination schedules of dogs and cats from World Small Animal Veterinary Association (WSAVA) and American Animal Hospital Association (AAHA). In 2010, WSAVA published guidelines for the vaccination of dogs and cats. And, in 2011, AAHA also published guidelines for vaccination of dogs. In Korea, there is no published guideline for vaccination of dogs and cats yet. Therefore, the plane of vaccination also reports the present situation of vaccination schedule of dogs and cats in Korean animal hospitals. PMID:25003099

2014-01-01

375

Infection of Domestic Dogs in Peru by Zoonotic Bartonella Species: A Cross-Sectional Prevalence Study of 219 Asymptomatic Dogs  

PubMed Central

Bartonella species are emerging infectious organisms transmitted by arthropods capable of causing long-lasting infection in mammalian hosts. Among over 30 species described from four continents to date, 15 are known to infect humans, with eight of these capable of infecting dogs as well. B. bacilliformis is the only species described infecting humans in Peru; however, several other Bartonella species were detected in small mammals, bats, ticks, and fleas in that country. The objective of this study was to determine the serological and/or molecular prevalence of Bartonella species in asymptomatic dogs in Peru in order to indirectly evaluate the potential for human exposure to zoonotic Bartonella species. A convenient sample of 219 healthy dogs was obtained from five cities and three villages in Peru. EDTA-blood samples were collected from 205 dogs, whereas serum samples were available from 108 dogs. The EDTA-blood samples were screened by PCR followed by nucleotide sequencing for species identification. Antibodies against B. vinsonii berkhoffii and B. rochalimae were detected by IFA (cut-off of 1?64). Bartonella DNA was detected in 21 of the 205 dogs (10%). Fifteen dogs were infected with B. rochalimae, while six dogs were infected with B. v. berkhoffii genotype III. Seropositivity for B. rochalimae was detected in 67 dogs (62%), and for B. v. berkhoffii in 43 (40%) of the 108 dogs. Reciprocal titers ?1?256 for B. rochalimae were detected in 19% of dogs, and for B. v. berkhoffii in 6.5% of dogs. This study identifies for the first time a population of dogs exposed to or infected with zoonotic Bartonella species, suggesting that domestic dogs may be the natural reservoir of these zoonotic organisms. Since dogs are epidemiological sentinels, Peruvian humans may be exposed to infections with B. rochalimae or B. v. berkhoffii. PMID:24040427

Diniz, Pedro Paulo V. P.; Morton, Bridget A.; Tngrian, Maryam; Kachani, Malika; Barron, Eduardo A.; Gavidia, Cesar M.; Gilman, Robert H.; Angulo, Noelia P.; Brenner, Elliott C.; Lerner, Richard; Chomel, Bruno B.

2013-01-01

376

Classifying dogs' (Canis familiaris) facial expressions from photographs.  

PubMed

Humans accurately read other humans' emotional facial expressions. Little research was found examining human ability to read dogs' expressions. Cross-species research extended facial expression research to chimpanzees, and there is much research on dogs' auditory signaling to humans. To explore humans' ability to identify dogs' facial displays, photographs of a dog's face were taken under behaviorally defined conditions expected to elicit specific emotions. Dog experts consistently rated these photographs. The photographs rated as best by experts were used as stimuli for people experienced and inexperienced with dogs. Both groups were able to read the dog's emotions. Paradoxically, experienced people were less accurate reading aggressiveness. Experienced people were better identifying behaviorally defined situations. Research using behaviorally anchored, standardized photographs is recommended. PMID:23485925

Bloom, Tina; Friedman, Harris

2013-06-01

377

The prevalence of Dirofilaria immitis in dogs in Kirikkale.  

PubMed

Heartworm infection is one of the most important parasitic diseases in dogs. The aim of the present study was to determine the prevalence of heartworm in dogs in Kirikkale. Blood samples of 172 dogs were collected. Microfilariae were detected in 10 (5.8%). dogs with the Knott technique. The anal and excretory pores stained with acid phosphates showed that the microfilariae belonged to Dirofilaria immitis. Microfilariae were found in dogs aged between 2-10 years, and especially in Siberian huskies, setters, pointers and crossbred sheepdogs. The serum samples of 142 dogs were analyzed using the commercial ELISA test kit for detection of anti-D. immitis antibody. The occult infection rate was found to be 27.46% in dogs. According to these results, Kirikkale region has a high risk for heartworm infection. PMID:18985575

Yildiz, Kader; Duru, Sibel Yasa; Ya?ci, Bu?rahan B; Ocal, Naci; Gazya?ci, Aycan N

2008-01-01

378

Social acknowledegments for children with disabilities: effects of service dogs.  

PubMed

While service dogs are known to perform important tasks for people using wheelchairs, such as retrieving dropped items or pulling a wheelchair, they may also serve as an antidote for social ostracism. Adults in wheelchairs have been found to receive many more social acknowledgements when a service dog is present than when not. This study examined whether disabled children in wheelchairs with service dogs receive more frequent social acknowledgment than when no dog is present. Behaviors of passersby in response to children in wheelchairs were recorded in shopping malls and on school playgrounds. In both settings, social acknowledegments (e.g., friendly glances, smiles, and conversations) were substantially more frequent when a service dog was present. Social effects of the dog were more pronounced in shopping malls, typical of unfamiliar settings where the child would be likely to experience being ignored or overlooked. Service dogs may assist in normalizing the social interactions for children with disabilities producing social isolation. PMID:2533060

Mader, B; Hart, L A; Bergin, B

1989-12-01

379

Laser lithotripsy for removal of uroliths in dogs  

NASA Astrophysics Data System (ADS)

Introduction: This study evaluated the ability to fragment and remove naturally occurring uroliths in dogs using a holmium: YAG laser. Methods: Twenty four dogs with naturally occurring uroliths including 10 spayed females and 14 neutered males. The dogs were 8.7 +/- 2.8 years old and weighed 13.7 +/- 8.0 kg. All dogs had bladder stones and 5 male dogs also had urethral stones. In female dogs, cystoscopy was performed using a rigid cystoscope with sheath diameter of 14 to 19 french. Cystoscopy was performed in males dogs using a 7.5 french diameter pediatric ureteroscope. Uroliths were fragmented using a 20 watt Holmium: YAG laser and the fragments were removed by basket extraction and voiding urohydropropulsion. Results: Average laser parameters for urolith fragmentation were 0.7 Joules at 8 Hertz (range: 0.5 to 1.3 Joules at 5 to 13 Hertz). All urolith fragments were successfully removed in all 10 female dogs and 11 of 14 male dogs. In one male dog, the urethra was too small to allow passage of the ureteroscope. In one of the male dogs, the urethral stones were successfully removed by laser lithotripsy, but removal of the bladder stones was performed by cystotomy. There was one complication of urethral perforation during attempts to pass an access sheath transurethrally in a dog with extensive proliferative urethritis. Conclusions: Laser lithotripsy is a safe and effective method of removing bladder and urethral stones in dogs provided the dog is large enough to permit transurethral passage of a cystoscope or ureteroscope.

Adams, Larry G.; Lulich, Jody P.

2006-02-01

380

Dog Therapy: The Importance of Just Being.  

ERIC Educational Resources Information Center

Excerpts from the book, "The Advantage of Being Useless"; anecdotes from the author's experiences; and observations of his dog illustrate how counselors can be so busy counseling that they miss the human connection. Outdoor activities are conducive to unself-conscious spontaneity and unconditional acceptance--a just "letting it happen," which…

Schusser, Eric

1998-01-01

381

Oral eosinophilic granuloma in Siberian husky dogs.  

PubMed

Oral eosinophilic granuloma in 6 young Siberian Husky dogs was characterized by involvement of lateral and ventral surfaces of the tongue. Histologically, the major change was degenerated (necrobiotic) collagen. Although the cause of the disease is unknown, hereditary and immunologic factors are implicated in the pathogenesis. PMID:7440364

Madewell, B R; Stannard, A A; Pulley, L T; Nelson, V G

1980-10-15

382

Fatal diphenhydramine poisoning in a dog.  

PubMed

We report a fatal diphenhydramine poisoning of a 10-year-old, male poodle-cross dog with pre-existing conditions and suspected co-ingestion of ethanol. This case illustrates that diphenhydramine overdose can be fatal in certain circumstances and that analytical toxicology may play an important role in animal death investigations. PMID:25392554

Buchweitz, John P; Raverty, Stephen A; Johnson, Margaret B; Lehner, Andreas F

2014-11-01

383

Dogs Don't Need Calculus  

ERIC Educational Resources Information Center

Many optimization problems can be solved without resorting to calculus. This article develops a new variational method for optimization that relies on inequalities. The method is illustrated by four examples, the last of which provides a completely algebraic solution to the problem of minimizing the time it takes a dog to retrieve a thrown ball,…

Bolt, Mike

2010-01-01

384

Intraocular Foreign Body in a Dog  

PubMed Central

An unusual clinical case of panophthalmitis in the dog is discussed. Failure of resolution led to enucleation. Histopathology study showed an intraocular foreign body, probably a grass awn, that had migrated into the eye and established a panophthalmitis. ImagesFigure 1.Figure 2.Figure 3.Figure 4. PMID:7340916

Bussanich, M. N.; Rootman, J.

1981-01-01

385

Rabies and African Wild Dogs in Kenya  

Microsoft Academic Search

Three packs of African wild dogs (Lycaon pictus) ranging to the north of the Masai Mara National Reserve in southwestern Kenya were monitored from 1988 to 1990. During a six week period (August 2-September 14, 1989), 21 of 23 members of one of these packs died. Histological examination of two brain samples revealed eosinophilic intracytoplasmic inclusions (Negri bodies), supporting a

P. W. Kat; K. A. Alexander; J. S. Smith; L. Munson

1995-01-01

386

Intravenous Infusion in Dogs and Primates  

Microsoft Academic Search

Continuous intravenous infusion allows the intended clinical dosing regime to be better evaluated during preclinical studies. Depending on the test material and vehicle, infusion for up to 6 months in primates and 12 months in beagle dogs is possible, but 28 days is the most frequent duration. Under general anesthesia, medical grade catheters are placed in the vena cava via

C. J. Perkin; R. Stejskal

1994-01-01

387

Heartworm in dogs in Canada in 1985.  

PubMed

In late December 1985, 1485 institutional veterinarians and small and mixed animal clinics across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1985 and 44% of them responded. Veterinarians reported that 137,300 dogs were blood-tested to check for microfilariae and 1210 dogs were found with heartworm. Another 36 dogs were amicrofilaremic but diagnosed with heartworm disease to give the total number diagnosed in 1985 as 1247 (0.91%).Heartworm was reported from all provinces except Prince Edward Island, Newfoundland and Saskatchewan but most (1126) of the cases were in Ontario. Southwestern Ontario continued to be the primary focus of the infection in Canada. From Quebec, 91 cases were reported mostly from and around Montreal. From Manitoba, 19 cases were reported from Winnipeg and surrounding areas. Heartworm was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 28% of the cases were observed with clinical signs of heartworm disease and 78% had a history of not having left Canada. PMID:17422691

Owen, J; Slocombe, D; McMillan, I

1986-09-01

388

Heartworm in dogs in Canada in 1987.  

PubMed

In late November 1987, 1246 institutional veterinarians and small and mixed animal clinics across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1987, and 50% of them responded. Veterinarians reported that 165,428 dogs were blood tested for heartworm disease and 511 dogs were found with D. immitis microfilariae. Another 78 dogs were amicrofilaremic but diagnosed with heartworm disease to give the total number of cases diagnosed in 1987 as 589 (0.35%).Heartworm was reported from British Columbia, Manitoba, Newfoundland, Ontario and Quebec, but most (478) of the cases were from Ontario. South-western Ontario continued to be the primary focus of the infection in Canada. There were 82 cases reported from Quebec, mostly from and around Montreal, and 23 from Manitoba, mostly from Winnipeg, Selkirk, and surrounding areas. Heartworm was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 29% of the cases were observed with clinical signs of heartworm disease and 81% had a history of not having left Canada. PMID:17423099

Slocombe, J O; McMillan, I

1988-08-01

389

Heartworm in dogs in Canada in 1984.  

PubMed

In late December 1984, 1853 institutional veterinarians and small and mixed animal clinics across Canada were sent a questionnaire in order to assess the status of Dirofilaria immitis in Canada in 1984 and 35% of them responded. Veterinarians reported that 97,794 dogs were blood-tested to check for microfilariae and 1417 dogs (1.45% of those tested) were found with heartworm. Another 34 dogs were amicrofilaremic, but were diagnosed as having heartworm disease, to give the total number diagnosed in 1984 as 1451 (1.48%). Heartworm was reported from all provinces except Prince Edward Island and Newfoundland but most (1310) of the cases were in Ontario. In Quebec, 126 cases were reported mostly from west of Montreal.Heartworm was found most frequently in companion dogs over three years of age maintained mainly outdoors in rural areas. About 27% of the cases were observed with clinical signs of heartworm disease and 72% had a history of not having left Canada. Southwestern Ontario continued to be the primary focus of the infection. PMID:17422583

Slocombe, J O; McMillan, I

1985-10-01

390

Do Dogs Know Calculus? Timothy J. Pennings  

E-print Network

Do Dogs Know Calculus? Timothy J. Pennings Tim Pennings (pennings@hope.edu) is an Associate, for an outing to Lake Michigan to play fetch with his favorite tennis ball. Standing on the water's edge (See. Finally, there is the option of running a portion of the way, and then plunging into the lake at D

Williams, Susan

391

Ebola Virus Antibody Prevalence in Dogs  

E-print Network

observed that several dogs were highly exposed to Ebola virus by eating infected dead animals. To examine whether these animals became infected with Ebola virus, we sampled 439 dogs and screened them by Ebola virus–specific immunoglobulin (Ig) G assay, antigen detection, and viral polymerase chain reaction amplification. Seven (8.9%) of 79 samples from the 2 main towns, 15 (15.2%) of 99 samples from Mekambo, and 40 (25.2%) of 159 samples from villages in the Ebola virus–epidemic area had detectable Ebola virus–IgG, compared to only 2 (2%) of 102 samples from France. Among dogs from villages with both infected animal carcasses and human cases, seroprevalence was 31.8%. A significant positive direct association existed between seroprevalence and the distances to the Ebola virus–epidemic area. This study suggests that dogs can be infected by Ebola virus and that the putative infection is asymptomatic. *Centre International de Recherches Médicales de Franceville,

Human Risk; Loďs Allela; Olivier Bourry; Régis Pouillot; André Délicat; Brice Kumulungui; Pierre Rouquet; Jean-paul Gonzalez; Eric M. Leroy

392

Prenatal olfactory learning in the domestic dog  

Microsoft Academic Search

The ability of individuals to learn about chemosensory stimuli in the prenatal, or immediate postnatal, period may be advan- tageous in acquiring information about ''safe'' foods after weaning. In this study, we examined the influence of perinatal exposure to aniseed via the mother's diet on a two-choice food test in the domestic dog. Pups were tested at 10 weeks of

Deborah L. Wells; Peter G. Hepper

2006-01-01

393

Ringworm by Microsporon gypseum in a dog  

Microsoft Academic Search

Summary The authors make a review ofM. gypseum infection in animals in Brazil. They relate a case of ringworm in a dog by this dermatophyte. They predict that the finding of animal ringworm by this fungus may be commoner in Brazil.

Olga Fischman; A. T. Londero; M. A. Santiago

1966-01-01

394

DOG AGGRESSION: CANINE BEHAVIOR AND FACTORS CONTRIBUTING TO AGGRESSION TOWARD HUMANS  

E-print Network

DOG AGGRESSION: CANINE BEHAVIOR AND FACTORS CONTRIBUTING TO AGGRESSION TOWARD HUMANS J. Kottferova1: kottfer@uvm.sk; Phone: 1421 915 984 670 Our study focused on dog aggression toward people dog owners about their dog's aggression toward unknown persons. More than half of the dogs surveyed

Champagne, Frances A.

395

Safety and efficacy of tolterodine extended release in men with overactive bladder symptoms and presumed non-obstructive benign prostatic hyperplasia  

Microsoft Academic Search

Patients with presumed non-obstructive BPH (Q\\u000a max ? 15 ml\\/s) treated with tolterodine ER 4 mg\\/day for OAB symptoms, alone or added to unsuccessful alpha-blocker treatment of\\u000a ?6 weeks duration, were observed for 12 weeks in a non-interventional study to generate real-life efficacy and safety data.\\u000a Patients completed the IPSS, the OAB-q and a 2-day micturition diary at baseline and 12 weeks. PVR was determined sonographically.\\u000a Seven

K. Höfner; M. Burkart; G. Jacob; U. Jonas

2007-01-01

396

How dogs know when communication is intended for them.  

PubMed

Domestic dogs comprehend human gestural communication in a way that other animal species do not. But little is known about the specific cues they use to determine when human communication is intended for them. In a series of four studies, we confronted both adult dogs and young dog puppies with object choice tasks in which a human indicated one of two opaque cups by either pointing to it or gazing at it. We varied whether the communicator made eye contact with the dog in association with the gesture (or whether her back was turned or her eyes were directed at another recipient) and whether the communicator called the dog's name (or the name of another recipient). Results demonstrated the importance of eye contact in human-dog communication, and, to a lesser extent, the calling of the dog's name--with no difference between adult dogs and young puppies--which are precisely the communicative cues used by human infants for identifying communicative intent. Unlike human children, however, dogs did not seem to comprehend the human's communicative gesture when it was directed to another human, perhaps because dogs view all human communicative acts as directives for the recipient. PMID:22356178

Kaminski, Juliane; Schulz, Linda; Tomasello, Michael

2012-03-01

397

STS-69 Crew members display 'Dog Crew' patches  

NASA Technical Reports Server (NTRS)

Following their arrival at KSC's Shuttle Landing Facility, the five astronauts assigned to Space Shuttle Mission STS-69 display the unofficial crew patch for their upcoming spaceflight: the Dog Crew II patch. Mission Commander David M. Walker (center) and Payload Commander James S. Voss (second from right) previously flew together on Mission STS-53, the final dedicated Department of Defense flight on the Space Shuttle. A close comradery formed among Walker, Voss and the rest of the crew, and they dubbed themselves the 'dogs of war', with each of the STS-53 'Dog Crew' members assigned a 'dog tag' or nickname. When the STS-69 astronauts also became good buddies, they decided it was time for the Dog Crew II to be named. Walker's dog tag is Red Dog, Voss's is Dogface, Pilot Kenneth D. Cockrell (second from left) is Cujo, space rookie and Mission Specialist Michael L. Gernhardt (left) is Under Dog, and Mission Specialist James H. Newman (right) is Pluato. The Dog Crew II patch features a bulldog peering out from a doghouse shaped like the Space Shuttle and lists the five crew member's dog names. The five astronauts are scheduled to lift off on the fifth Shuttle flight of the year at 11:04 a.m. EDT, August 31, aboard the Space Shuttle Endeavour.

1995-01-01

398

Pemphigus foliaceus in dogs: a review of 37 cases.  

PubMed

Thirty-seven dogs with pemphigus foliaceus were seen over a span of 9 years in a veterinary medical teaching hospital. Four breeds of dogs (Bearded Collie, Akita, Newfoundland, Schipperke) were at significant elevated risk when compared with both the dermatology canine case population and the hospital canine population. The mean age of onset was 4.2 years. The dorsal part of the muzzle was the most common site of initial involvement in over 50% of the dogs, and lesions of the head were seen first in 81% of the dogs. Disease progression was gradual (greater than 3 months) in 73% of the dogs. Somewhat bilaterally symmetric scaling, crusting, and alopecia were seen in all of the dogs. Vesicles, pustules, and bullae were not seen commonly, but target lesions with peripheral collarettes were seen frequently. Most dogs had characteristic footpad lesions, with erythematous swelling at the pad margins, cracking, and villous hypertrophy. Generalized exfoliative dermatitis was seen in dogs with widespread disease. Pruritus was noted in less than one half of the dogs. Typical histopathologic findings included subcorneal and intragranular cell layer epidermal pustules, or intrafollicular pustules with prominent acantholysis. Direct immunofluorescence in an intercellular pattern was noted in 76% of the dogs tested and indirect immunofluorescence was noted in 75% of a much smaller sample. Thirty-nine percent of the dogs responded to corticosteroid therapy alone, and 50% and 55% responded, respectively, to prednisone and cytotoxic drugs, and to prednisone with aurothioglucose. Aurothioglucose was successful alone in 27% of the dogs. One-year survival was achieved in 53% of the dogs. PMID:3880732

Ihrke, P J; Stannard, A A; Ardans, A A; Griffin, C E

1985-01-01

399

SOCIAL GROUP FISSION AND GENE DYNAMICS AMONG BLACK-TAILED PRAIRIE DOGS  

E-print Network

SOCIAL GROUP FISSION AND GENE DYNAMICS AMONG BLACK-TAILED PRAIRIE DOGS (CYNOMYS LUDOVICIANUS fission. Key words: coancestry, competition, cooperation, Cynomys ludovicianus, dispersal, fission, gene al. 1990). Black-tailed prairie dogs (Cynomys ludovicianus; hereafter, simply ``prairie dogs

Foltz, David W.

400

49 CFR 236.338 - Mechanical locking required in accordance with locking sheet and dog chart.  

Code of Federal Regulations, 2012 CFR

...accordance with locking sheet and dog chart. 236.338 Section 236.338 Transportation...accordance with locking sheet and dog chart. Mechanical locking shall be in accordance with locking sheet and dog chart currently in...

2012-10-01

401

49 CFR 236.338 - Mechanical locking required in accordance with locking sheet and dog chart.  

Code of Federal Regulations, 2011 CFR

...accordance with locking sheet and dog chart. 236.338 Section 236.338 Transportation...accordance with locking sheet and dog chart. Mechanical locking shall be in accordance with locking sheet and dog chart currently in...

2011-10-01

402

49 CFR 236.338 - Mechanical locking required in accordance with locking sheet and dog chart.  

Code of Federal Regulations, 2013 CFR

...accordance with locking sheet and dog chart. 236.338 Section 236.338 Transportation...accordance with locking sheet and dog chart. Mechanical locking shall be in accordance with locking sheet and dog chart currently in...

2013-10-01

403

49 CFR 236.338 - Mechanical locking required in accordance with locking sheet and dog chart.  

Code of Federal Regulations, 2010 CFR

...accordance with locking sheet and dog chart. 236.338 Section 236.338 Transportation...accordance with locking sheet and dog chart. Mechanical locking shall be in accordance with locking sheet and dog chart currently in...

2010-10-01

404

33 CFR 147.839 - Mad Dog Truss Spar Platform safety zone.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Mad Dog Truss Spar Platform safety zone. 147...ACTIVITIES SAFETY ZONES § 147.839 Mad Dog Truss Spar Platform safety zone. (a) Description. Mad Dog Truss Spar Platform, Green Canyon 782...

2010-07-01

405

33 CFR 147.839 - Mad Dog Truss Spar Platform safety zone.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Mad Dog Truss Spar Platform safety zone. 147...ACTIVITIES SAFETY ZONES § 147.839 Mad Dog Truss Spar Platform safety zone. (a) Description. Mad Dog Truss Spar Platform, Green Canyon 782...

2012-07-01

406

33 CFR 147.839 - Mad Dog Truss Spar Platform safety zone.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Mad Dog Truss Spar Platform safety zone. 147...ACTIVITIES SAFETY ZONES § 147.839 Mad Dog Truss Spar Platform safety zone. (a) Description. Mad Dog Truss Spar Platform, Green Canyon 782...

2011-07-01

407

33 CFR 147.839 - Mad Dog Truss Spar Platform safety zone.  

...2014-07-01 2014-07-01 false Mad Dog Truss Spar Platform safety zone. 147...ACTIVITIES SAFETY ZONES § 147.839 Mad Dog Truss Spar Platform safety zone. (a) Description. Mad Dog Truss Spar Platform, Green Canyon 782...

2014-07-01

408

33 CFR 147.839 - Mad Dog Truss Spar Platform safety zone.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Mad Dog Truss Spar Platform safety zone. 147...ACTIVITIES SAFETY ZONES § 147.839 Mad Dog Truss Spar Platform safety zone. (a) Description. Mad Dog Truss Spar Platform, Green Canyon 782...

2013-07-01

409

Dog breed stereotype and exposure to negative behavior: effects on perceptions of adoptability.  

PubMed

The purpose of the study was to determine if brief exposure to a dog behaving badly or in a friendly manner affects subsequent perceptions of the target dog's and other dogs' adoptability. Participants viewed a videotape of an adoptable German shepherd behaving either aggressively or prosocially and were then asked to rate the characteristics and adoptability of the same and different dogs. The results showed that people who saw the aggressive behavioral schema perceived only the target dog and a dog of the same breed to be significantly less adoptable than dogs of other breeds (p<.01). Results of a principal components analysis showed participants perceived the adoptability of dogs to be related to "sociability": Adoptable dogs were more approachable, friendly, intelligent, and less dangerous and aggressive (p<.01). Brief exposure to a misbehaving dog prior to making a decision to adopt may unfairly penalize other dogs perceived to be similar to the misbehaving dog. PMID:17645409

Wright, John C; Smith, Alison; Daniel, Katie; Adkins, Karen

2007-01-01

410

Dog obesity: can dog caregivers' (owners') feeding and exercise intentions and behaviors be predicted from attitudes?  

PubMed

Dog obesity is a common nutritional disorder affecting up to 40% of the companion animal (pet) dog population in Australia and other developed nations. A clear understanding of factors determining relevant caregiver (owner) behaviors underpins effective treatment for this disorder. The theory of planned behavior can be used to understand factors contributing to human behavior. This article describes research informed by this theory. The research examined relationships between owners' behavioral beliefs and barriers, normative beliefs and perceptions of control, owners' feeding and exercise behaviors toward their dogs, and the body condition scores (BCSs) of dogs. The study recruited a sample of 182 dog and owner dyads. The researcher independently assessed BCSs. Owners completed a questionnaire measuring relevant feeding and exercise beliefs and behaviors. This revealed significant correlations between many psychological variables and BCSs and between psychological variables and specific owner behaviors: for example, the relationship of low levels of intentions to feed appropriately to ambivalent beliefs toward feeding appropriately and low perceived control. Careful consideration of the specific variables identified will permit the development of more effective interventions. PMID:20563903

Rohlf, Vanessa I; Toukhsati, Samia; Coleman, Grahame J; Bennett, Pauleen C

2010-01-01

411

Survival of Skin Graft between Transgenic Cloned Dogs and Non-Transgenic Cloned Dogs  

PubMed Central

Whereas it has been assumed that genetically modified tissues or cells derived from somatic cell nuclear transfer (SCNT) should be accepted by a host of the same species, their immune compatibility has not been extensively explored. To identify acceptance of SCNT-derived cells or tissues, skin grafts were performed between cloned dogs that were identical except for their mitochondrial DNA (mtDNA) haplotypes and foreign gene. We showed here that differences in mtDNA haplotypes and genetic modification did not elicit immune responses in these dogs: 1) skin tissues from genetically-modified cloned dogs were successfully transplanted into genetically-modified cloned dogs with different mtDNA haplotype under three successive grafts over 63 days; and 2) non-transgenic cloned tissues were accepted into transgenic cloned syngeneic recipients with different mtDNA haplotypes and vice versa under two successive grafts over 63 days. In addition, expression of the inserted gene was maintained, being functional without eliciting graft rejection. In conclusion, these results show that transplanting genetically-modified tissues into normal, syngeneic or genetically-modified recipient dogs with different mtDNA haplotypes do not elicit skin graft rejection or affect expression of the inserted gene. Therefore, therapeutically valuable tissue derived from SCNT with genetic modification might be used safely in clinical applications for patients with diseased tissues. PMID:25372489

Kim, Geon A; Oh, Hyun Ju; Kim, Min Jung; Jo, Young Kwang; Choi, Jin; Park, Jung Eun; Park, Eun Jung; Lim, Sang Hyun; Yoon, Byung Il; Kang, Sung Keun; Jang, Goo; Lee, Byeong Chun

2014-01-01

412

Characterization of the dog agouti gene and a nonagouti mutation in german shepherd dogs  

SciTech Connect

The interaction between two genes, Agouti and Melanocortin-1 receptor (Mc1r), produces diverse pigment patterns in mammals by regulating the type, amount, and distribution pattern of the two pigment types found in mammalian hair: eumelanin (brown/black) and pheomelanin (yellow/red). In domestic dogs (Canis familiaris), there is a tremendous variation in coat color patterns between and within breeds; however, previous studies suggest that the molecular genetics of pigment-type switching in dogs may differ from that of other mammals. Here we report the identification and characterization of the Agouti gene from domestic dogs, predicted to encode a 131-amino-acid secreted protein 98 percent identical to the fox homolog, and which maps to chromosome CFA24 in a region of conserved linkage. Comparative analysis of the Doberman Pinscher Agouti cDNA, the fox cDNA, and 180 kb of Doberman Pinscher genomic DNA suggests that, as with laboratory mice, different pigment-type-switching patterns in the canine family are controlled by alternative usage of different promoters and untranslated first exons. A small survey of Labrador Retrievers, Greyhounds, Australian Shepherds, and German Shepherd Dogs did not uncover any polymorphisms, but we identified a single nucleotide variant in black German Shepherd Dogs predicted to cause an Arg-to-Cys substitution at codon 96, which is likely to account for recessive inheritance of a uniform black coat.

Kerns, Julie A.; Newton, J.; Berryere, Tom G.; Rubin, Edward M.; Cheng, Jan-Fang; Schmutz, Sheila M.; Barsh, Gregory S.

2004-07-08

413

Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs.  

PubMed

The interaction between two genes, Agouti and Melanocortin-1 receptor ( Mc1r), produces diverse pigment patterns in mammals by regulating the type, amount, and distribution pattern of the two pigment types found in mammalian hair: eumelanin (brown/black) and pheomelanin (yellow/red). In domestic dogs ( Canis familiaris), there is a tremendous variation in coat color patterns between and within breeds; however, previous studies suggest that the molecular genetics of pigment-type switching in dogs may differ from that of other mammals. Here we report the identification and characterization of the Agouti gene from domestic dogs, predicted to encode a 131-amino-acid secreted protein 98% identical to the fox homolog, and which maps to chromosome CFA24 in a region of conserved linkage. Comparative analysis of the Doberman Pinscher Agouti cDNA, the fox cDNA, and 180 kb of Doberman Pinscher genomic DNA suggests that, as with laboratory mice, different pigment-type-switching patterns in the canine family are controlled by alternative usage of different promoters and untranslated first exons. A small survey of Labrador Retrievers, Greyhounds, Australian Shepherds, and German Shepherd Dogs did not uncover any polymorphisms, but we identified a single nucleotide variant in black German Shepherd Dogs predicted to cause an Arg-to-Cys substitution at codon 96, which is likely to account for recessive inheritance of a uniform black coat. PMID:15520882

Kerns, Julie A; Newton, J; Berryere, Tom G; Rubin, Edward M; Cheng, Jan-Fang; Schmutz, Sheila M; Barsh, Gregory S

2004-10-01

414

Response and adaptation of Beagle dogs to hypergravity  

NASA Technical Reports Server (NTRS)

Eight male Beagle dogs, five months old, were centrifuged continuously for three months at progressively increasing loads. Heart rate and deep body temperature were monitored continuously by implant biotelemetry. Initially, centrifuged dogs showed transient decreases in heart rate and body temperature along with changes in their diurnal rhythm patterns. Compared with normal gravity controls, exposed dogs showed a slower growth rate and a reduced amount of body fat. Blood protein, total lipids, cholesterol, calcium, packed cell volume, red blood cell count, and hemoglobin were also decreased significantly. Absolute weights of the leg bones of centrifuged dogs were significantly greater than controls. Photon absorptiometry revealed significant density increases in selective regions of the femur and humerus of centrifuged dogs. In spite of the various changes noted, results from this and other studies affirm the view that dogs can tolerate and adapt to sustained loads as high as 2.5 g without serious impairment of their body structure and function.

Oyama, J.

1975-01-01

415

Radiotherapy of metastatic seminoma in the dog. Case reports  

SciTech Connect

Four dogs with metastatic seminoma were treated with cesium 137 teleradiotherapy. Minimum total tumor dose ranged from 17 to 40 gray (Gy) and was usually given through bilateral opposing sublumbar ports in eight to ten fractions, with three fractions given weekly. The tumor regressed in all four dogs. The first dog (case 1) was free of tumor and died of non-tumor related causes at 57 months. The second dog (case 2) was free of tumor but was euthanatized at 37 months for a limb fracture. The third dog (case 3) was euthanatized for undertermined pulmonary disease 43 months after radiotherapy. The fourth dog (case 4) was euthanatized 6 months following radiotherapy because of transitional cell carcinoma and renal failure. No evidence of seminoma was found at necropsy. Radiotherapy was shown to be effective treatment for seminoma with regional metastasis.

McDonald, R.K.; Walker, M.; Legendre, A.M.; vanEe, R.T.; Gompf, R.E.

1988-04-01

416

Evidence of an oncogenic gammaherpesvirus in domestic dogs  

SciTech Connect

In humans, chronic infection with the gammaherpesvirus Epstein-Barr virus is usually asymptomatic; however some infected individuals develop hematological and epithelial malignancies. The exact role of EBV in lymphomagenesis is poorly understood partly because of the lack of clinically relevant animal models. Here we report the detection of serological responses against EBV capsid antigens in healthy dogs and dogs with spontaneous lymphoma and that dogs with the highest antibody titers have B cell lymphoma. Moreover, we demonstrate the presence of EBV-like viral DNA and RNA sequences and Latent Membrane Protein-1 in malignant lymph nodes of dogs with lymphoma. Finally, electron microscopy of canine malignant B cells revealed the presence of classic herpesvirus particles. These findings suggest that dogs can be naturally infected with an EBV-like gammaherpesvirus that may contribute to lymphomagenesis and that dogs might represent a spontaneous model to investigate environmental and genetic factors that influence gammaherpesvirus-associated lymphomagenesis in humans.

Huang, Shih-Hung, E-mail: ncku309@gmail.com [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States)] [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States); Kozak, Philip J., E-mail: philj@vet.upenn.edu [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States); Kim, Jessica, E-mail: jesskim820@gmail.com [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States)] [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States); Habineza-Ndikuyeze, Georges, E-mail: georgesh@vet.upenn.edu [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States)] [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States); Meade, Charles, E-mail: cmeade@vet.upenn.edu [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States)] [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States); Gaurnier-Hausser, Anita, E-mail: anitag@vet.upenn.edu [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States)] [Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 335 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States); Patel, Reema, E-mail: rtpatel@vet.upenn.edu [Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 315 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States)] [Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 315 Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104-6010 (United States); Robertson, Erle, E-mail: erle@mail.med.upenn.edu [Department of Microbiology, and Abramson Comprehensive Cancer Center, Tumor Virology Program, University of Pennsylvania, 202A Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104-6076 (United States)] [Department of Microbiology, and Abramson Comprehensive Cancer Center, Tumor Virology Program, University of Pennsylvania, 202A Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104-6076 (United States); and others

2012-06-05

417

Serum butyrylcholinesterase activity in dogs with diabetes mellitus.  

PubMed

Increased serum butyrylcholinesterase (BChE) activity is a feature of diabetes mellitus (DM) in humans and rats. The objective of this study was to evaluate serum BChE activity in diabetic dogs. The activity of the enzyme was assessed in three cohorts of animals: (1) dogs with naturally occurring DM (n=74); (2) clinically normal dogs (n=74); and (3) dogs with various other diseases (n=74). A statistically significant increase in BChE activity was found in the diabetic dogs (7.59 ± 2.9 kUI/L) compared with the clinically normal animals (6.12 ± 1.94 kUI/L; P<0.05), and with the dogs with other diseases (5.55 ± 2.06 kUI/L; P<0.01). Such increased activity could be the result of the altered glucose and lipid metabolism that occurs in DM. PMID:21820337

Tvarijonaviciute, A; Ceron, J J; Caldin, M

2012-06-01

418

All About the Dogs 4-H Weekend -2012 In June, the Rolling Bones 4-H Dog Club of Merrimack county held its fifteenth  

E-print Network

All About the Dogs 4-H Weekend - 2012 In June, the Rolling Bones 4-H Dog Club of Merrimack county held its fifteenth annual All About the Dogs weekend at the 4-H Youth Center in New Boston, NH. This clinic provides a canine training-themed weekend for children enrolled in the 4-H Dog Program

New Hampshire, University of

419

Leading the Pack: Dog 3--Fun Activities for You and Your Dog. 4-H Skills for Life Animal Series. National 4-H Curriculum. BU-08168  

ERIC Educational Resources Information Center

Experienced youth investigate responsible breeding, diseases, caring for geriatric dogs, training, service dogs, dog roles and careers related to dogs. This guide provides youth with numerous leadership opportunities. Because youth development programs help build tomorrow's leaders, leadership is a strong theme in Level 3 activities. One will be…

National 4-H Council, 2005

2005-01-01

420

SOURCE: http://articles.cnn.com/2010-11-18/living/intelligent.dog.psychology_1_dogs-brian-hare-problems?_s=PM:LIVING accessed 12 Nov 2012  

E-print Network

SOURCE: http://articles.cnn.com/2010-11-18/living/intelligent.dog.psychology_1_dogs-brian-hare- problems?_s=PM:LIVING accessed 12 Nov 2012 Inside the science of how dogs think CNN Living: WORLD November toy! Ever wonder what your dog is thinking as it gazes at you while you are barking commands? Duke

Packard, Jane M.

421

Children's behavior toward and understanding of robotic and living dogs  

Microsoft Academic Search

This study investigated children's reasoning about and behavioral interactions with a computationally sophisticated robotic dog (Sony's AIBO) compared to a live dog (an Australian Shepherd). Seventy-two children from three age groups (7–9 years, 10–12 years, and 13–15 years) participated in this study. Results showed that more children conceptualized the live dog, as compared to AIBO, as having physical essences, mental states, sociality, and

Gail F. Melson; Peter H. Kahn Jr.; Alan Beck; Batya Friedman; Trace Roberts; Erik Garrett; Brian T. Gill

2009-01-01

422

The seeing-eye dog: an infection risk in hospital?  

PubMed Central

Because an increasing number of blind people are using guide dogs, hospital administrators may receive more frequent requests to allow a guide dog to accompany its blind owner during visit with a hospital patient. This article considers the risks and problems for all concerned if seeing-eye dogs are permitted in hospitals, and proposes a reasonable set of guidelines for hospital personnel to apply when considering these requests. PMID:7471013

Hardy, G J

1981-01-01

423

Hydrocolpos in dogs: surgical treatment in two cases.  

PubMed

Two young female dogs were diagnosed with hydrocolpos as a result of a congenital vaginal obstruction. In one dog, hydrocolpos had led to faecal tenesmus; in the other, the condition was an incidental finding during laparotomy. Diagnostic tests included vaginoscopy, ultrasonography and retrograde vagino-urethrocystography. In both dogs, the obstruction was located at the junction between the caudal vagina and the vaginal vestibule. Anastomosis of the caudal vagina and vestibule through an episiotomy was successful in both cases. PMID:14510330

Viehoff, F W; Sjollema, B E

2003-09-01

424

Prevalence of Dirofilaria immitis infection in dogs from Dandong, China  

Microsoft Academic Search

The aim of the present study was to estimate the prevalence and risk factors of Dirofilaria immitis infection in dogs from Dandong, China. A total of 886 dogs were examined for D. immitis infection by microscopic examination and PCR, indicating that the prevalence was 16.6% (213\\/886) and 24.0% (147\\/886), respectively. The odds of infection were significantly higher in older dogs

Honglie Hou; Guoshun Shen; Wei Wu; Pengtao Gong; Quan Liu; Juan You; Yanan Cai; Jianhua Li; Xichen Zhang

425

Prevalence of dirofilarial infection in raccoon dogs in Japan  

Microsoft Academic Search

The raccoon dog (Nyctereutes procyonoides viverrinus) is known to acquire canine heartworm (Dirofilaria immitis) infection. We surveyed the prevalence of heartworm infection in free-ranging raccoon dogs in the Nishi-Tama (Tokyo) and Kanagawa areas of Japan. A total of 75 raccoon dog carcasses, including 29 animals from the Nishi-Tama area and 46 from the Kanagawa area, were necropsied between 1992 and

Kazuhide Nakagaki; Takashi Suzuki; Shin Ichi Hayama; Eiji Kanda

2000-01-01

426

Ultrasonographic characteristics of the abdominal esophagus and cardia in dogs.  

PubMed

Differential diagnoses for regurgitation and vomiting in dogs include diseases of the gastroesophageal junction. The purpose of this cross-sectional study was to describe ultrasonographic characteristics of the abdominal esophagus and gastric cardia in normal dogs and dogs with clinical disease involving this region. A total of 126 dogs with no clinical signs of gastrointestinal disease and six dogs with clinical diseases involving the gastroesophageal junction were included. For seven euthanized dogs, ultrasonographic features were also compared with gross pathology and histopathology. Cardial and abdominal esophageal wall thicknesses were measured ultrasonographically for all normal dogs and effects of weight, sex, age, and stomach filling were tested. Five layers could be identified in normal esophageal and cardial walls. The inner esophageal layer was echogenic, corresponding to the cornified mucosa and glandular portion of the submucosa. The cardia was characterized by a thick muscularis, and a transitional zone between echogenic esophageal and hypoechoic gastric mucosal layers. Mean (±SD) cardial wall thicknesses for normal dogs were 7.6 mm (±1.6), 9.7 mm (±1.8), 10.8 mm (±1.6), 13.3 mm (±2.5) for dogs in the <10 kg, 10-19.9 kg, 20-29.9 kg and ?30 kg weight groups, respectively. Mean (±SD) esophageal wall thicknesses were: 4.1 mm (±0.6), 5.1 mm (±1.3), 5.6 mm (±1), and 6.4 mm (±1.1) for the same weight groups, respectively. Measurements of wall thickness were significantly correlated with dog weight group. Ultrasonography assisted diagnosis in all six clinically affected dogs. Findings supported the use of transabdominal ultrasonography as a diagnostic test for dogs with suspected gastroesophageal disease. PMID:24629089

Gory, Guillaume; Rault, Delphine N; Gatel, Laure; Dally, Claire; Belli, Patrick; Couturier, Laurent; Cauvin, Eddy

2014-09-01

427

Lymphocytic insulitis in a juvenile dog with diabetes mellitus  

Microsoft Academic Search

Autoimmune diabetes has never been described in a juvenile dog, whereas serologica evidence has established its development\\u000a in adult dogs. Diabetes mellitus was diagnosea in a 3-mo-old Donge de Bordeaux dog suffering from persistent hyperglycemia\\u000a and concurrent insulinopenia. Histological analysis of the pancreas revealed in flammatory lesions in 40% of the islets of\\u000a Lagerhans, with infiltration predominantly by T lymphocytes

G. Jouvion; J. Abadie; J. M. Bach; F. Roux; J. Miclard; J. Y. Deschamps; L. Guigand; P. Saď; M. Wyers

2006-01-01

428

Relationship between atrial fibrillation and primary hypothyroidism in the dog.  

PubMed

Atrial fibrillation (AF) and primary hypothyroidism are most often diagnosed in middle-aged and older dogs of large and giant breeds. We hypothesized that the frequency of primary hypothyroidism may be higher in dogs with AF than in those without AF. Two groups were investigated. Group 1 (March 1987-June 1990) consisted of 128 dogs with AF. A thyroid-stimulating hormone (TSH) stimulation test was performed in dogs with a low voltage on the ECG and low uptake of pertechnetate on a thyroid scan. Group 2 (July 1990-July 1991) consisted of both dogs with AF (n = 38) and control dogs (n = 235) in which plasma thyroxine (T4) was measured. If T4 was below 15 nmol/l, a TSH stimulation test was performed. The frequencies of primary hypothyroidism in group 1 (8/128) and in the group 2 AF dogs (3/38) were not different, but were higher than in the control animals (3/235) (P < 0.05). The group 1 and the group 2 AF dogs were found to be comparable, and pooling of the data of the two groups enhanced the significance of the frequency of primary hypothyroidism in dogs with AF versus the control animals (11/166 versus 3/235) (P < 0.01). We concluded that the frequency of primary hypothyroidism in dogs with AF is higher than in the group of control dogs without AF. This may be due to the additional cardiovascular changes accompanying primary hypothyroidism in dogs that already have heart disease. PMID:8792593

Gerritsen, R J; van den Brom, W E; Stokhof, A A

1996-06-01

429

Plasma Cortisol Levels of Dogs at a County Animal Shelter  

Microsoft Academic Search

Hennessy, M. B., H. N. Davis, M. T. Williams, C. Mellott and C. W. Douglas. Plasma cortisol levels of dogs in a county animal shelter. Physiol Behav 62(3) 485–490, 1997.—Plasma cortisol levels were examined to assess the stress of dogs in a county animal shelter. Groups of dogs confined in the shelter for their 1st, 2nd, or 3rd day had

Michael B Hennessy; Harry N Davis; Michael T Williams; Carolyn Mellott; Chet W Douglas

1997-01-01

430

Planning and operational considerations for units utilizing military working dogs.  

PubMed

Military working dogs are rapidly becoming integral to military operations. While they bring many valuable capabilities to the battlefield, it is important that Special Operations leaders consider canine team capabilities and requirements when planning missions. Careful logistical and operational planning can optimize the health, performance, and readiness of the working dog while protecting the safety and well-being of the team members working with them. We also offer recommendations for medical treatment of dog bites. PMID:19813342

Royal, Joseph; Taylor, Charles L

2009-01-01

431

A Comparison of Tethering and Pen Confinement of Dogs  

Microsoft Academic Search

This study compared general activity and specific behaviors of 30 adult Alaskan sled dogs, 19 male and 11 female dogs, on 3.5 m tethers and in 5.9 m2 pens. The investiga- tors used activity level and steriotypies as indicators of welfare. The dogs spent most of their time inactive, either lying or sitting both on the tether and in the

Seong C. Yeon; Glen Golden; Wailani Sung; Hollis N. Erb; Arleigh J. Reynolds; Katherine A. Houpt

2001-01-01

432

Ancient DNA evidence for Old World origin of New World dogs.  

PubMed

Mitochondrial DNA sequences isolated from ancient dog remains from Latin America and Alaska showed that native American dogs originated from multiple Old World lineages of dogs that accompanied late Pleistocene humans across the Bering Strait. One clade of dog sequences was unique to the New World, which is consistent with a period of geographic isolation. This unique clade was absent from a large sample of modern dogs, which implies that European colonists systematically discouraged the breeding of native American dogs. PMID:12446908

Leonard, Jennifer A; Wayne, Robert K; Wheeler, Jane; Valadez, Raúl; Guillén, Sonia; Vilŕ, Carles

2002-11-22

433

Renal parameter estimates in unrestrained dogs  

NASA Technical Reports Server (NTRS)

A mathematical formulation has been developed to describe the hemodynamic parameters of a conceptualized kidney model. The model was developed by considering regional pressure drops and regional storage capacities within the renal vasculature. Estimation of renal artery compliance, pre- and postglomerular resistance, and glomerular filtration pressure is feasible by considering mean levels and time derivatives of abdominal aortic pressure and renal artery flow. Changes in the smooth muscle tone of the renal vessels induced by exogenous angiotensin amide, acetylcholine, and by the anaesthetic agent halothane were estimated by use of the model. By employing totally implanted telemetry, the technique was applied on unrestrained dogs to measure renal resistive and compliant parameters while the dogs were being subjected to obedience training, to avoidance reaction, and to unrestrained caging.

Rader, R. D.; Stevens, C. M.

1974-01-01

434

Respiratory epithelial adenomatoid hamartoma in a dog.  

PubMed

A 6-month-old, intact, male Weimaraner dog presented to the veterinary teaching hospital for bilateral mucopurulent ocular and nasal discharge that began at approximately 10 weeks of age. A computed tomography scan showed an expansile soft-tissue mass involving both frontal sinuses, the ethmoid regions, and nasal cavities with lysis of the maxillary turbinates and hyperostosis of the walls of the frontal sinus. The dog was euthanized after complications during a trephination and biopsy procedure. At necropsy, a large, tan, papillary, gelatinous mass filled the entire nasal cavity and frontal sinus. The mass was composed of large fronds of loose fibrovascular stroma covered by a single layer of pseudostratified, columnar, ciliated epithelium and intermixed goblet cells. The cells occasionally formed glandular structures that were continuous with the surface epithelium. The mass was diagnosed as a respiratory epithelial adenomatoid hamartoma based on the morphologic appearance. PMID:19901304

Leroith, Tanya; Binder, Ellen M; Graham, A Heather; Duncan, Robert B

2009-11-01

435

In Vitro Culture of 'Dog Ridge' Grapevine  

E-print Network

as UNDERGRADUATE RESEARCH SCHOLAR A Senior Scholars Thesis by KAH-YAT ISAAC WONG IN VITRO CULTURE OF ?DOG RIDGE? GRAPEVINE Approved by: Research Advisor: R. Daniel Lineberger Associate Dean for Undergraduate Research: Robert C. Webb... Major: Horticulture April 2009 Submitted to the Office of Undergraduate Research Texas A&M University in partial fulfillment of the requirements for the designation as UNDERGRADUATE RESEARCH SCHOLAR A Senior Scholars Thesis by KAH-YAT ISAAC...

Wong, Kah-Yat Isaac

2009-06-09

436

The history of a catatonic dog  

Microsoft Academic Search

This article is a condensed life-history of a dog (“V3”) born and reared in the Pavlovian Laboratory and studied until his\\u000a death in 1961. A detailed study was made of his pathologic development, his relations to people, and the effects of drugs.\\u000a Measurements recorded were heart rate, blood pressure, respiration, 24-hour activity, sexual reflexes, general behavior. Although\\u000a early experiments were

Joseph E. O. Newton; W. Horsley Gantt

1968-01-01

437

Toxicokinetics of labeled amatoxins in the dog  

Microsoft Academic Search

Radioactivities were measured in serum, urine, and bile of dogs at different times after intravenous injection of 14C-methyl-?-amanitin (14C-A) and 3H-O-methyl-dehydroxy methyl-?-amanitin (3H-A). For either substance, the relation between the specific plasma activity C and the time t could be best described with the function \\u000a $$C = C_1 \\\\cdot e^{ - \\\\lambda _1 \\\\cdot t} + C_2 \\\\cdot e^{ -

H. Faulstich; A. Talas; H. H. Wellhöner

1985-01-01

438

Salmonella organisms in mature, healthy dogs  

E-print Network

studies and proved to be klhaligsnss, Proteus and par-colons. Three additional culturea that were identified as proteus required fourteen days to demonstrate uraaae activity. Eighteen cultures identified as Salmonella did not show ureasa activity... doubt that tha seam need exists in ths plants manufacturing tbs finished feeds. 11 Bacteria of Cbe genus proteus aru troublesome vien culturing dog faces for Salmonella. Eighty tuo psr cant of three hundred attempts Co isolate Sahsonslla yielded...

Jungerman, Paul F

2012-06-07

439

The healing power of dogs: Cocoa's story.  

PubMed

Animals bring a sense of "at homeness" and even normalcy to people who are hospitalized or live in health care facilities. Illnesses, separation from family, fear, loneliness, and even depression may be lessened for those who receive a therapy dog visit by providing a welcome change in routine and something to look forward to. Individuals are often more active and responsive during and after a visit. Just stroking and petting a dog requires the use of hands and arms, as well as the motions of stretching and turning. Dogs are also unconcerned with age or physical ability; they accept people as they are. This alone causes many to reach out and interact with dogs. Animals provide a focus for conversation and a common interest. As Cocoa's human partner can attest, a pet also makes it easier for strangers to talk. Cocoa is known by so many people at the facilities she visits that residents' family members often stop to talk with "Cocoa's mom" when they meet her in the community, asking questions about how Cocoa is doing. When Cocoa is no longer able to perform her services, many in her community will mourn. Cocoa's story, as well as the limited research literature, supports the positive physical and psychological effects of animals, but continued research on the effect of therapy animals on health outcomes is needed. As advocates for clients, nurses are in key positions to facilitate the inclusion of animals in clients' care. Although not for everyone, including those who react negatively to animals or who are allergic, pet therapy offers important possibilities for providing holistic care that extends not only to clients, but also to family members and staff, and to the pets themselves. PMID:16475440

Cangelosi, Pamela R; Embrey, Carolyn N

2006-01-01

440

Risk factors for development of chronic superficial keratitis in dogs.  

PubMed

Proportional hospital accession ratios for chronic superficial keratitis (CSK) of dogs were determined for 16 US veterinary teaching hospitals participating in the Veterinary Medical Data Base between Jan 1, 1976 and Dec 31, 1991. The prevalence of CSK was significantly correlated (r = 0.90) with altitude of residence, but not with latitude, longitude, mean annual solar radiation, or mean annual relative humidity. Medical records of dogs with (n = 595) and without (n = 72,877) CSK examined at the Colorado State University Veterinary Teaching Hospital between Jan 1, 1976 and Oct 28, 1991 were also reviewed. Belgian Tervuren, German Shepherd Dogs, Border Collies, Greyhounds, Siberian Huskies, and Australian Shepherds were disproportionately affected. Dogs between 4 and 7 years old were 2.36 times more likely to develop lesions than were dogs < 4 years old (P < 0.05). Among dogs < 4 years old, spayed females, sexually intact males, and castrated males were more likely to develop the condition (P < 0.05) than were sexually intact females. Altitude of residence was a significant risk factor in the development of CSK among dogs in Colorado. Dogs living at altitudes > 7,000 ft above sea level were 7.75 times more likely to develop lesions than were dogs living at elevations between 3,000 and 5,000 ft. PMID:8050943

Chavkin, M J; Roberts, S M; Salman, M D; Severin, G A; Scholten, N J

1994-05-15

441

Science Sampler: You can learn a lot from your dog  

NSDL National Science Digital Library

Recently, dogs have been the focus of a great deal of scientific research. In fact, dogs were the inspiration for Professor Bruce Blumberg's class, The Cognitive Dog: Savant or Slacker, at Harvard University. This course serves as the impetus for the thematic unit presented here--You Can Learn A Lot From Your Dog. The unit incorporates cooperative learning, data analysis, and presentations while providing a powerful approach to teaching science. This unit is meaningful for middle school students as they develop an understanding of selected aspects of the inquiry process.

Worsham, Sherry

2007-11-01

442

HUNT STABLE COMPLEX LOOKING NORTHWEST TOWARD DOG KENNEL RUINS ACROSS ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HUNT STABLE COMPLEX LOOKING NORTHWEST TOWARD DOG KENNEL RUINS ACROSS THE GREAT CIRCUS - Overhills, Fort Bragg Military Reservation, Approximately 15 miles NW of Fayetteville, Overhills, Harnett County, NC

443

Association between passive smoking and atopic dermatitis in dogs.  

PubMed

Onset of atopic dermatitis and occurrence of related skin lesions are influenced by various environmental factors in humans, and companion animals. Several studies have demonstrated an association between passive smoking and the development of atopic dermatitis in children. This association has never been investigated in the dog to our knowledge. We enrolled 161 dogs seen at dermatology and vaccination consultations over a six-month period for this study. Dog owners were asked to complete a questionnaire, to evaluate the exposure of the dog to tobacco smoke. The atopic or non-atopic status of the dog was assessed on the basis of Favrot's criteria (history, clinical examination and cutaneous cytology for Malassezia). Analysis of the data for the 161 dogs enrolled revealed a significant association between high levels of passive exposure to tobacco smoke (cigarette consumption divided by the area of the home) and the presence of atopic dermatitis in the dogs (OR, 4.38; 95% CI, 1.10-17.44; p=0.03; NNH (number needed to harm) 3, 95% CI 2-52). The prevalence of atopic dermatitis showed a slight, but non-significant association with breed predisposition. Dogs with high levels of exposure to tobacco smoke may have a higher risk of atopic dermatitis than non-exposed dogs. PMID:24491262

Ka, D; Marignac, G; Desquilbet, L; Freyburger, L; Hubert, B; Garelik, D; Perrot, S

2014-04-01

444

Survival and clinical outcome of dogs with ischaemic stroke.  

PubMed

The objectives of the present study were to investigate survival time, possible predictors of survival and clinical outcome in dogs with ischaemic stroke. A retrospective study of dogs with a previous diagnosis of ischaemic stroke diagnosed by magnetic resonance imaging (MRI) was performed. The association between survival and the hypothesised risk factors was examined using univariable exact logistic regression. Survival was examined using Kaplan-Meier and Cox regression. Twenty-two dogs were identified. Five dogs (23%) died within the first 30days of the stroke event. Median survival in 30-day survivors was 505days. Four dogs (18%) were still alive by the end of the study. Right-sided lesions posed a significantly increased risk of mortality with a median survival time in dogs with right-sided lesions of 24days vs. 602days in dogs with left sided lesions (P=0.006). Clinical outcome was considered excellent in seven of 17 (41%) 30-day survivors. Another seven 30-day survivors experienced new acute neurological signs within 6-17months of the initial stroke event; in two of those cases a new ischaemic stroke was confirmed by MRI. In conclusion, dogs with ischaemic stroke have a fair to good prognosis in terms of survival and clinical outcome. However, owners should be informed of the risk of acute death within 30days and of the possibility of new neurological events in survivors. Mortality was increased in dogs with right-sided lesions in this study. PMID:23206661

Gredal, H; Toft, N; Westrup, U; Motta, L; Gideon, P; Arlien-Sřborg, P; Skerritt, G C; Berendt, M

2013-06-01

445

A practical dog bed for environmental enrichment for geriatric beagles, with applications for puppies and other small dogs.  

PubMed

A group of 30 older beagle dogs was acquired for aging studies. The dogs were initially housed in kennel runs equipped with elevated benches, but it became apparent that some of the oldest animals had difficulties jumping down from them. To improve animal safety and comfort, practical dog beds were made out of the ends of clean high-density polyethylene barrels. Synthetic fleece bed liners were used for dogs that did not chew them or remove them from the beds. Nine of the beagles regularly were observed to use the beds. We also have found that this easily fashioned dog bed is a useful kennel resting place option for puppies and other small dogs. PMID:11353524

Eisele, P H

2001-05-01

446

"Dog pox": some clinical aspects of an eruptive condition of certain mucous surfaces in dogs.  

PubMed

An eruptive condition seen on certain mucous membranes of dogs occurs frequently but often asymptomatically. Lesions have been found to be present in over 60 percent of male dogs. The infection is probably due to a canine herpes virus and has been termed conveniently but inaccurately "dog pox". In many cases lesions are present without observable clinical signs but severe irritation, especially related to lesions in the lower bowel, can give rise to marked symptoms which may be confused with abnormality of the para-anal sacs, or to chronic diarrhoea of a type suggestive of colitis. The incidence, sites of infection and possible syndromes which may be ascribed to the condition are briefly discussed on a clinical basis only. PMID:165610

Joshua, J O

1975-04-01

447

Attributes of specialist search dogs--a questionnaire survey of UK dog handlers and trainers.  

PubMed

The ideal and actual characteristics of specialist search dogs have been examined in questionnaire surveys of 244 dog handlers and trainers from the six main UK dog-using Government agencies. The ten most important characteristics were (ideal level in brackets): acuity of sense of smell (very high), incentive to find an object which is out of sight (very high), health (very high), tendency to hunt by smell alone (very high), stamina (very high), ability to learn from being rewarded (very high), tendency to be distracted when searching (very low); agility (high), consistency of behaviour from day to day (high), motivation to chase an object (high). Significant differences between actual and ideal levels were found for 22 of the 30 characteristics, predominantly in undesirable attributes, suggesting that there is scope for significant improvement in operational effectiveness. PMID:15027550

Rooney, Nicola J; Bradshaw, John W S; Almey, Helen

2004-03-01

448

Probable essential thrombocythemia in a dog  

SciTech Connect

Essential thrombocythemia (ET), in an 11-year-old dog was characterized by persistently high platelet counts range, 4.19 X 10(6)/microliters to 4.95 X 10(6)/microliters, abnormal platelet morphology, marked megakaryocytic hyperplasia in the bone marrow, absence of circulating megakaryoblasts, and history of splenomegaly and gastrointestinal bleeding. Increased numbers of megakaryocytes and megakaryoblasts (15% to 20%) in the bone marrow were confirmed by a positive acetylcholinesterase reaction. Another significant finding was the presence of a basophilia in blood (4,836/microliters) and bone marrow. The marked persistent thrombocytosis, absence of reactive (secondary) thrombocytosis, abnormal platelet morphology, and quantitative and qualitative changes in the megakaryocytic series in the bone marrow suggested the presence of a myeloproliferative disease. Cytochemical and ultrastructural findings aided in the diagnosis of ET. The dog was treated with radiophosphorus. The results was a rapid decline in the numbers of megakaryoblasts and megakaryocytes in the bone marrow and platelets and basophils in the peripheral blood. The dog died unexpectedly of acute necrotizing pancreatitis and diabetes mellitus before a complete remission was achieved.

Hopper, P.E.; Mandell, C.P.; Turrel, J.M.; Jain, N.C.; Tablin, F.; Zinkl, J.G.

1989-04-01

449

Canine kobuvirus infections in Korean dogs.  

PubMed

To investigate canine kobuvirus (CaKoV) infection, fecal samples (n = 59) were collected from dogs with or without diarrhea (n = 21 and 38, respectively) in the Republic of Korea (ROK) in 2012. CaKoV infection was detected in four diarrheic samples (19.0 %) and five non-diarrheic samples (13.2 %). All CaKoV-positive dogs with diarrhea were found to be infected in mixed infections with canine distemper virus and canine parvovirus or canine adenovirus. There was no significant difference in the prevalence of CaKoV in dogs with and without diarrhea. By phylogenetic analysis based on partial 3D genes and complete genome sequences, the Korean isolates were found to be closely related to each other regardless of whether they were associated with diarrhea, and to the canine kobuviruses identified in the USA and UK. This study supports the conclusion that CaKoVs from different countries are not restricted geographically and belong to a single lineage. PMID:24906525

Oem, Jae-Ku; Choi, Jeong-Won; Lee, Myoung-Heon; Lee, Kyoung-Ki; Choi, Kyoung-Seong

2014-10-01

450

Demographic and ecological survey of dog population in aba, abia state, Nigeria.  

PubMed

Dog ecology is essential in understanding the distribution, structure, and population density of dogs and pattern of dog ownership in any given area. A cross-sectional study was designed to study dog ecology in Aba, Abia state, Nigeria, from April to June 2013. The study revealed that the 500 households surveyed possessed 5,823 individuals and 747 dogs, giving a dog to human ratio of 1?:?7.8; hence dog population in Aba was estimated to be 68,121. About 495/747 (66.3%) of the dogs were exotic and 465/747 (62.2%) were males. A total of 319/500 (63.8%) of the households had fences that restrained dog movement and there was no incidence of dog bite in 447/500 (89.4%) of the households surveyed. There were statistical associations between vaccination against antirabies and breeds of dogs (? (2) = 79.8, df = 2, P < 0.005). Exotic breed (adjusted OR = 0.39; CI = 0.23-0.65) and local breed of dogs (adjusted OR = 0.08; CI = 0.04-0.14) had less odds of being vaccinated as compared to crossbreed of dogs. About 126 dogs (2.5 dogs per street) were estimated from street counts survey. The relative high dog to human ratio and low vaccination coverage of owned dogs population pose public health concerns requiring adequate public health education and proper antirabies vaccination coverage of dogs in the study area. PMID:25002978

Otolorin, Gbeminiyi Richard; Umoh, Jarlath U; Dzikwi, Asabe Adamu

2014-01-01

451

Craniomandibular Trauma and Tooth Loss in Northern Dogs and Wolves: Implications for the Archaeological Study of Dog Husbandry and Domestication  

PubMed Central

Archaeological dog remains from many areas clearly show that these animals suffered tooth fractures, tooth loss, trauma, and dental defects during their lives. Relatively little research has explored the meanings of these patterns, particularly for ancient dog remains from small-scale societies of the North. One limiting issue is the lack of comparative data on dental health and experiences of trauma among northern wolves and dogs. This paper examines tooth loss, tooth fracture, enamel hypoplasia, and cranial trauma in a large sample of historic dog and wolf remains from North America and Northern Russia. The data indicate that the dogs more commonly experienced tooth loss and tooth fracture than the wolves, despite reportedly being fed mostly soft foods such as blubber and fish. The higher rates observed in the dogs likely is a result of food stress and self-provisioning through scavenging. The ability to self-provision was likely important for the long-term history of dog use in the north. Dogs also more commonly experienced cranial fractures than wolves, particularly depression fractures on their frontal bones, which were likely the result of blows from humans. Hypoplastic lesions are rare in both wolves and dogs, and probably result from multiple causes, including food stress, disease, and trauma. PMID:24941003

Losey, Robert J.; Jessup, Erin; Nomokonova, Tatiana; Sablin, Mikhail

2014-01-01

452

Methamphetamine intoxication in a dog: case report  

PubMed Central

Background Methamphetamine abuse has undergone a dramatic worldwide increase, and represents a significant and global issue for public health. Incidents of methamphetamine intoxication and death in humans are relatively commonplace. Because of its increasing illicit availability, together with legitimate use in human medicine, accidental or intentional exposure to methamphetamine in dogs is becoming a more likely scenario. Case presentation A 3-year-old, 3.7 kg intact female Miniature Poodle who had been intentionally fed an unknown amount of a crystalline-like substance developed extreme agitation, seizures, tachycardia, hyperthermia, hypertension, disseminated intravascular coagulation (DIC), bloody diarrhea, and dilated pupils. Blood work revealed leukocytosis, erythropenia, lymphocytosis, thrombocytopenia, coagulation abnormalities, but all to a mild extent, together with mild elevation in both alanine aminotranferease (ALT) and alkaline phosphatase (ALKP), and a mild decreased in glucose. Radiologic diagnosis revealed generalized, severe distension of the stomach and small intestinal tract with air. Immunochromatographic screening tests and gas chromatography mass spectrometry analysis confirmed methamphetamine intoxication and revealed concentrations of methamphetamine in blood and urine of 0.32 ?g/mL and 2.35 ?g/mL respectively. The dog demonstrated progressive improvement after supportive care, with the high fever resolved over the initial 24 hours of hospitalization, and agitation was successfully controlled beyond 48 hours after initial hospitalization. Hemostatic abnormalities were progressive improved after heparin therapy and supportive care. By the sixth day of hospitalization the dog was clinically well, and all laboratory data had returned to normal with the exception of a mild elevateion of ALKP. Conclusion To the authors’ knowledge, this is the second case report of methamphetamine intoxication in dogs presented in veterinary practice in open literature so far. Although rare, methamphetamine intoxication should be considered as a differential diagnosis in dogs with a toxic substance ingestion history and with typical nervous and cardiovascular system symptoms. In such cases rapid diagnosis and aggressive intervention is important for prognosis. Blood methamphetamine concentration may be a helpful value for assessment of the severity of intoxication and prediction of clinical outcomes. PMID:24962469

2014-01-01

453

Reactivity to intradermal injections of extracts of house dust and housedust mite in healthy dogs and dogs suspected of being atopic.  

PubMed

Fifty dogs underwent intradermal allergy testing with housedust mite and house dust extracts, using concentrations recommended by the manufacturer. Twelve dogs (group I) were healthy dogs obtained from a pound; 12 dogs (group II) were healthy, privately owned dogs; 15 dogs (group III) were suspected of being atopic and had had multiple positive reactions to intradermal injections of allergens of specific trees, weeds, grasses, or molds; and 11 dogs (group IV) were suspected of being atopic, but only had had positive reactions to intradermal injections of housedust mite, house dust, and flea antigen extracts. Use of the concentrations of housedust mite and house dust extracts currently recommended for intradermal allergy testing resulted in false-positive reactions in 14 of 24 (58%) and 12 of 24 (50%) healthy dogs tested, respectively. Differences in number of dogs with positive reactions or grade of reaction to housedust mite or house dust allergens were not detected between groups of healthy dogs (groups I vs II), between groups of suspected atopic dogs (groups III vs IV), or between healthy dogs and dogs suspected of being atopic (groups I and II vs III and IV). Therefore, clinical importance of positive results of intradermal allergy testing of house dust or housedust mite allergens was equivocal for dogs suspected of being atopic. Threshold concentrations for intradermal allergy testing were determined in 24 healthy dogs (group I and II) by intradermal administration of 5 dilutions each of housedust mite extract and house dust extract.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7759333

Codner, E C; Tinker, M K

1995-03-15

454

Energy Requirements of Adult Dogs: A Meta-Analysis  

PubMed Central

A meta-analysis was conducted to determine the maintenance energy requirements of adult dogs. Suitable publications were first identified, and then used to generate relationships amongst energy requirements, husbandry, activity level, methodology, sex, neuter status, dog size, and age in healthy adult dogs. Allometric equations for maintenance energy requirements were determined using log-log linear regression. So that the resulting equations could readily be compared with equations reported by the National Research Council, maintenance energy requirements in the current study were determined in kcal/kg0.75 body weight (BW). Ultimately, the data of 70 treatment groups from 29 publications were used, and mean (± standard deviation) maintenance energy requirements were 142.8±55.3 kcal.kgBW?0.75.day?1. The corresponding allometric equation was 81.5 kcal.kgBW?0.93.day?1 (adjusted R2?=?0.64; 70 treatment groups). Type of husbandry had a significant effect on maintenance energy requirements (P<0.001): requirements were greatest in racing dogs, followed by working dogs and hunting dogs, whilst the energy requirements of pet dogs and kennel dogs were least. Maintenance energy requirements were less in neutered compared with sexually intact dogs (P<0.001), but there was no effect of sex. Further, reported activity level tended to effect the maintenance energy requirement of the dog (P?=?0.09). This review suggests that estimating maintenance energy requirements based on BW alone may not be accurate, but that predictions that factor in husbandry, neuter status and, possibly, activity level might be superior. Additionally, more information on the nutrient requirements of older dogs, and those at the extremes of body size (i.e. giant and toy breeds) is needed. PMID:25313818

Bermingham, Emma N.; Thomas, David G.; Cave, Nicholas J.; Morris, Penelope J.; Butterwick, Richard F.; German, Alexander J.

2014-01-01

455

Humans Process Dog and Human Facial Affect in Similar Ways  

PubMed Central

Humans share aspects of their facial affect with other species such as dogs. Here we asked whether untrained human observers with and without dog experience are sensitive to these aspects and recognize dog affect with better-than-chance accuracy. Additionally, we explored similarities in the way observers process dog and human expressions. The stimulus material comprised naturalistic facial expressions of pet dogs and human infants obtained through positive (i.e., play) and negative (i.e., social isolation) provocation. Affect recognition was assessed explicitly in a rating task using full face images and images cropped to reveal the eye region only. Additionally, affect recognition was assessed implicitly in a lexical decision task using full faces as primes and emotional words and pseudowords as targets. We found that untrained human observers rated full face dog expressions from the positive and negative condition more accurately than would be expected by chance. Although dog experience was unnecessary for this effect, it significantly facilitated performance. Additionally, we observed a range of similarities between human and dog face processing. First, the facial expressions of both species facilitated lexical decisions to affectively congruous target words suggesting that their processing was equally automatic. Second, both dog and human negative expressions were recognized from both full and cropped faces. Third, female observers were more sensitive to affective information than were male observers and this difference was comparable for dog and human expressions. Together, these results extend existing work on cross-species similarities in facial emotions and provide evidence that these similarities are naturally exploited when humans interact with dogs. PMID:24023954

Schirmer, Annett; Seow, Cui Shan; Penney, Trevor B.

2013-01-01

456

Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs.  

PubMed

Loteprednol etabonate, a new glucocorticoid soft drug with a characteristic chloromethyl ester function in the 17 beta-position, is currently in the early phases of clinical development. As the basis for human trials, this study describes a new reversed-phase high-performance liquid chromatographic method for the determination of levels of drug in plasma and urine samples and assesses the pharmacokinetic properties of loteprednol etabonate in dogs and rats. Intravenous administration of loteprednol etabonate (5 mg/kg) to dogs revealed a terminal half-life of 2.8 h, a volume of distribution of 3.7 L/kg, and a total body clearance of 0.9 L/h/kg. Intact loteprednol etabonate was not detectable in the urine. After oral administration of the drug (5 mg/kg) to dogs, only metabolites, but no intact drug, were found in the plasma, an indication for a high first-pass effect. A pronounced binding of the drug to plasma protein (> 90%) and a high erythrocyte-buffer partition coefficient of 7.8 were determined in vitro. Preliminary information about tissue distribution and possible metabolic pathways were obtained in rats after oral administration of a 14C-labeled loteprednol etabonate suspension (5 mg/kg). pH-selective extraction into ethyl acetate revealed three distinguishable fractions: (1) a neutral lipophilic fraction, presumably intact drug, (2) an acidic, lipophilic fraction, and (3) a hydrophilic nonextractable fraction. Levels of intact drug and metabolites were highest in liver and kidney, whereas significantly lower levels were found in other investigated organs (lung, brain, heart).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1491342

Hochhaus, G; Chen, L S; Ratka, A; Druzgala, P; Howes, J; Bodor, N; Derendorf, H

1992-12-01

457

The role of pet dogs in casual conversations of elderly adults.  

PubMed

Casual conversations were recorded as elderly persons routinely walked their dogs through a familiar mobile home park in the United States. Control observations included walks without dogs by owners and non-owners of dogs. All owners talked to and about their dogs. Transcribed conversations indicated that dogs were a primary focus of conversation. A majority of sentences to dogs were imperatives; the owners were instructing the dogs. Dog owners frequently included dogs' names or nicknames in their sentences when they spoke to the dogs and made reference to the dogs' wishes or needs. Speaking to dogs was also associated with frequent repetition of sentences. Passersby talked to the owners about their dogs whether or not the dogs were present. When dog owners spoke with other people, their conversations often concerned activities that were occurring in the present, whereas conversations of non-owners focused on stories about past events. Dog owners reported taking twice as many daily walks as non-owners. Dog owners also reported significantly less dissatisfaction with their social, physical and emotional states. PMID:8412041

Rogers, J; Hart, L A; Boltz, R P

1993-06-01

458

Dogs show left facial lateralization upon reunion with their owners.  

PubMed

Domestic dogs demonstrate behavioral laterality in response to emotional stimuli; those responses include tail wagging and head turning. The dog is the species with the closest relationship to humans; dogs can express strong social emotions (e.g., attachment and separation anxiety) to specific persons, such as their owners. In this study, we examined whether dogs demonstrate more facial laterality when reunited with their owners than when they encounter an unfamiliar person in an unfamiliar situation. We also examined whether the observed laterality was specific to positive social stimuli (i.e., the owner) or a general response to nonsocial positive stimuli (i.e., toys). The dogs' facial expressions were recorded by a high-speed video camera during the presentation of emotional stimuli and the acceleration rates of parts of their faces were analyzed. The results showed that the left eyebrow moved more when the owner was present than at baseline. No bias in terms of eyebrow movement was observed when the dogs saw attractive toys. These results suggest that dogs show facial laterality in response to emotional stimuli. This laterality was specific to social stimuli, probably reflecting the dog's attachment to the owner. PMID:23727034

Nagasawa, Miho; Kawai, Emi; Mogi, Kazutaka; Kikusui, Takefumi

2013-09-01

459

Inhibition of glycolysis by L-sorbose in dog erythrocytes  

Microsoft Academic Search

Summary We have demonstrated previously that in vitro L-sorbose acts directly on dog erythrocytes to induce hemolysis. Here we report that L-sorbose depresses lactate formation in dog hemolysates from glucose, mannose and fructose but not from glucose-6-phosphate and galactose, suggesting that L-sorbose interacts with glycolysis at the level of the hexokinase.

A. Kistler; P. Keller

1978-01-01

460

Experimental infection of dogs with the nasal mite Pneumonyssoides caninum.  

PubMed

A successful experimental transmission of the canine nasal mite, Pneumonyssoides caninum, is described. Some 11 weeks after repeated systemic ivermectin treatment, four Beagles were inoculated via the right nostril with 20 P. caninum mites of different sexes and life stages, obtained at the necropsy of an infected dog. The inoculated dogs and a matching uninoculated control were observed for clinical signs for 14 weeks and then euthanised. Vague upper respiratory signs and a transient minor increase in the number of eosinophils in peripheral blood were recorded in the inoculated dogs. At necropsy 4-12 P. caninum mites were found in the nasal cavities and sinuses of the inoculated dogs, but none in the control. In three out of the four infected dogs mites were found in both the right and left nasal cavities and sinuses of the skull. Since in no case more mites than the number used for inoculation were detected it is not clear if the mites managed to reproduce in the dogs. Inflammatory lesions were seen most consistently in the olfactory mucosa, respiratory mucosa and tonsils, and growth of opportunistic bacteria was observed in the tonsils of the infected dogs. The inflammatory lesions seen in the olfactory mucosa may explain why dogs infected with P. caninum sometimes appear to suffer from impaired scenting ability. PMID:9746287

Gunnarsson, L; Zakrisson, G; Lilliehook, I; Christensson, D; Rehbinder, C; Uggla, A

1998-06-15

461

Lipoma in the Mediastinum of a Prairie Dog (Cynomys ludovicianus)  

Microsoft Academic Search

A large, firm lipoma was found in the cranial mediastinum of a 3-year-old female prairie dog (Cynomys ludovicianus). It encompassed the carotid arteries, jugular veins, and thymus, and compressed the esophagus and trachea. Localized compression caused dysphagia, weight loss, and dyspnea, which eventually resulted in death. Most reports on prairie dogs involve their use in research on gallbladder contractility and

KAREN L. ROGERS; CLARENCE E. CHRISP

462

Novel amdoparvovirus infecting farmed raccoon dogs and arctic foxes.  

PubMed

A new amdoparvovirus, named raccoon dog and fox amdoparvovirus (RFAV), was identified in farmed sick raccoon dogs and arctic foxes. Phylogenetic analyses showed that RFAV belongs to a new species within the genus Amdoparvovirus of the family Parvoviridae. An RFAV strain was isolated in Crandell feline kidney cell culture. PMID:25417672

Shao, Xi-Qun; Wen, Yong-Jun; Ba, Heng-Xing; Zhang, Xiu-Ting; Yue, Zhi-Gang; Wang, Ke-Jian; Li, Chun-Yi; Qiu, Jianming; Yang, Fu-He

2014-12-01

463

Estimation of roaming dog populations in Timor Leste.  

PubMed

The continued spread of rabies through the eastern islands of Indonesia poses a risk of rabies introduction to Timor Leste. To prepare for such an incursion and to undertake surveillance activities, the size and distribution of the roaming dog population needs to be estimated. We present the results of the first such surveys ever undertaken in Timor Leste. Roaming dog surveys were undertaken in each capital of the 13 districts of Timor Leste, including the national capital, Dili. Within these locations, local urban areas (aldeias) were targeted and sight-re-sight counts were undertaken on consecutive days. Estimated dog populations were adjusted for the sampling fraction. Overall, counts were performed in a total of 53 of 131 (40.5%) sucos and in 192 of 797 (24.1%) aldeias in these selected sucos. Within the surveyed urban areas, there were an estimated 21.2 people per roaming dog, a ratio substantially higher than the World Health Organization's average global estimate of 10 people per dog. The highest populations of dogs were estimated in the cities of Dili (4919), Baucau vila (3449) and Lospalos (2536). The latter two are important because of their location in the northeast of Timor Leste, where the risk of rabies incursion from recently infected islands in eastern Indonesia, is likely greatest. The sight-resight method of estimating roaming dog populations is practical in developing countries; more use of photography to aid resighting of dogs could increase the accuracy of this method. PMID:24360218

Amaral, Acáçio Cardoso; Ward, Michael P; da Costa Freitas, Joana

2014-03-01

464

Did that Dog Sniff Violate the Fourth Amendment?  

ERIC Educational Resources Information Center

Is sniffing at the front door of a private home by a trained narcotics detection dog a Fourth Amendment search requiring probable cause? Is a "drug dog" somehow like a manmade technology, such as a thermal imaging device? These were a couple of the questions recently presented to the U.S. Supreme Court during arguments in "Florida v. Jardines."…

Hawke, Catherine; Middleton, Tiffany

2012-01-01

465

Translation of new cancer treatments from pet dogs to humans  

Microsoft Academic Search

Naturally occurring cancers in pet dogs and humans share many features, including histological appearance, tumour genetics, molecular targets, biological behaviour and response to conventional therapies. Studying dogs with cancer is likely to provide a valuable perspective that is distinct from that generated by the study of human or rodent cancers alone. The value of this opportunity has been increasingly recognized

Melissa Paoloni; Chand Khanna

2008-01-01

466

Nuclear angiography in a dog with congestive cardiomyopathy  

SciTech Connect

Nuclear angiography was used as a diagnostic aid and in monitoring the clinical course of a case of congestive cardiomyopathy in a dog. Serial examinations revealed progressively deteriorating values for left ventricular ejection fraction before the dog's death. This noninvasive technique can be an alternative to echocardiography for the evaluation of cardiac performance.

Lippert, A.C.; Twardock, A.R.; Gelberg, H.B.

1986-03-01

467

Immunization coverage required to prevent outbreaks of dog rabies  

Microsoft Academic Search

WHO recommends that 70% of dogs in a population should be immunized to eliminate or prevent outbreaks of rabies. This critical percentage (pc) has been established empirically from observations on the relationship between vaccination coverage and rabies incidence in dog populations around the world. Here, by contrast, we estimate pc by using epidemic theory, together with data available from four

Paul G. Coleman; Christopher Dye

1996-01-01

468

Investigating financial aspects of dog-fighting in the UK  

Microsoft Academic Search

Purpose – The purpose of this paper is to discuss financial aspects of illegal dog-fighting in the UK and to reflect upon and discuss the difficulties of researching illegal entrepreneurial activities such as dog-fighting which are operated for criminal profit. Such activities are conducted by urban criminals often in a rural setting. Such crimes invariably occur in a closed social

Robert Smith

2011-01-01

469

Morphometric analysis of parathyroid glands in neonatal and growing dogs  

Microsoft Academic Search

In dogs aged 6 days or 5 months, the parathyroid (PT) glands exhibited differences of both the distribution and ultrastructure of dark and light cells. Morphometric estimates of cytoplasm, nucleus, mitochondria, rough endoplasmic reticulum (rER), Golgi apparatus, secretory granules, lysosomes and plasma membranes of both dark and light cells were obtained by point counting volumetry from PT glands of dogs

P. Wild; E. Manser

1980-01-01

470

Cocaethylene formation in rat, dog, and human hepatic microsomes  

Microsoft Academic Search

The dog and rat are important animal models for studying the role of cocaethylene in the pharmacodynamic interaction between cocaine and ethanol. In a previous study in our laboratory it was found that a cocaine dose of 3 mg\\/kg IV and ethanol 1 g\\/kg IV failed to produce detectable concentrations of cocaethylene in the plasma of dogs. In follow up

Ning Song; Robert B. Parker; S. Casey Laizure

1999-01-01

471

Animal Health Diagnostic Center Lyme Disease Multiplex Testing for Dogs  

E-print Network

Animal Health Diagnostic Center Lyme Disease Multiplex Testing for Dogs Background on Lyme disease Lyme Multiplex Assay was developed at the Animal Health Diagnostic Center at Cornell University of a warm-blooded host, such as dogs, horses, or humans (Fig. 2). In response to infection, #12;Animal

Keinan, Alon

472

Disseminated aspergillosis in a dog due to Aspergillus alabamensis  

PubMed Central

Disseminated aspergillosis is uncommon in dogs and often associated with Aspergillus terreus. A case of disseminated disease in an English springer spaniel is reported from which Aspergillus alabamensis was recovered by culture and identified by molecular means suggesting a potential role for this agent as a primary pathogen of dogs. PMID:24371723

Burrough, Eric; Deitz, Krysta; Kinyon, Joann; Andreasen, Claire; Frana, Timothy; Sutton, Deanna; Thompson, Elizabeth; Fu, Jianmin; Wickes, Brian; Hostetter, Jesse

2012-01-01

473

Children's Behavior toward and Understanding of Robotic and Living Dogs  

ERIC Educational Resources Information Center

This study investigated children's reasoning about and behavioral interactions with a computationally sophisticated robotic dog (Sony's AIBO) compared to a live dog (an Australian Shepherd). Seventy-two children from three age groups (7-9 years, 10-12 years, and 13-15 years) participated in this study. Results showed that more children…

Melson, Gail F.; Kahn, Peter H., Jr.; Beck, Alan; Friedman, Batya; Roberts, Trace; Garrett, Erik; Gill, Brian T.

2009-01-01

474

A Folk Tale of a Dog and a Pauper  

E-print Network

Folk Tale of a Dog and a Pauper Translation of title Description (to be used in archive entry) Dbal bzang provides a folktale in which a dog helps a pauper to become a very rich man. Genre or type (i.e. epic, song, ritual) Interview...

Bkra shis bzang po

2009-10-30

475

270. OFFICERS' QUARTERS (FORMER SUMMER COTTAGES) AT DOG PATCH BEACH, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

270. OFFICERS' QUARTERS (FORMER SUMMER COTTAGES) AT DOG PATCH BEACH, C. 1939. VIEW NORTH DOWN GREENWICH ROAD TOWARD FORMER SUMMER COTTAGES, CONVERTED TO OFFICER'S QUARTERS, OVER-LOOKING DOG PATCH BEACH. - Quonset Point Naval Air Station, Roger Williams Way, North Kingstown, Washington County, RI

476

Blindfolded dogs relocate a target through path integration  

Microsoft Academic Search

We investigated whether dogs, Canis familiaris, can relocate a briefly presented food target after having been led away from it, by relying on feedback from locomotion (path integration). Dogs were led blindfolded and with earphones into a large symmetrical enclosure. Sitting at a location near the periphery of the enclosure, the subject could see the experimenter throw a food item

Jennifer Cattet; Ariane S. Etienne

2004-01-01

477

Sex-biased dispersal in African wild dogs, Lycaon pictus  

Microsoft Academic Search

Sex differences in African wild dog dispersal behaviour have been described variously as strongly female biased to unbiased. Dispersal from natal home ranges to reproductive home ranges was recorded over 5 years from eight study packs in a free-ranging population of wild dogs in northern Botswana. Analysis of sex differences in natal dispersal was based on (1) age of natal

J. WELDON McNUTT

1996-01-01

478

Acoustic stimulation as a tool in African wild dog conservation  

Microsoft Academic Search

A 9-year study of the African wild dog, Lycaon pictus, was conducted in Hwange National Park, Zimbabwe, primarily in Colophospermum mopane woodland and Combretum thicket. A protocol using both playbacks and human simulations of long distance calls was developed to facilitate radio-collaring operations and data collection. Wild dogs were known to be in the area prior to each trial (n=32).

Robert L. Robbins; E. Kim McCreery

2003-01-01

479

The ecology of dog bite injury in St. Louis, Missouri.  

PubMed Central

A detailed analysis of all the reported dog bites that occurred over a 2-year period in St. Louis, Mo., provided new insight not only into the severity of the problem, but also the environmental context for injury. Dog bite is a major medical problem that affects at least 1 of every 222 people and specifically 1 of every 83 children, 5 to 9 years old. Nearly 20 percent of all the children bitten were injured on the head or face, a source of concren and expense for all concerned. Nearly 10 percent of all bites were classified as serious. In only 25 percent of all injuries did the victim's behabior involve the dog at the time ofe victim interacting with the dog's owner. The victim was on the dog owner's property in about u9 percent of the incidents, and in about 48 percent of the cases the bite took pla-e near the owner's property. Bite incidents go up whenever the weather is conductive to street activity. More than 85 percent of all the biting dogs had owners. These results indicate that society's views of dog bite injury, which tend to minimize the problem and find fault with the victim, must be re-evaluated. It is time to place less emphasis on the victim and even the animal and review thae public health implications of dog ownership Images p264-a p265-a p267-a PMID:807942

Beck, A M; Loring, H; Lockwood, R

1975-01-01

480

Viral Antibody Patterns in Laboratory Dogs With Respiratory Disease.  

National Technical Information Service (NTIS)

Serologic tests were carried out to determine the occurrence of viral infections in 169 dogs during a 3-week conditioning period after their arrival at a laboratory. One hundred twenty-three (72.8%) of the dogs developed respiratory disease and 22 (13.0%)...

L. N. Binn, E. C. Lazar, J. Helms, R. E. Cross

1969-01-01

481

Shock collars used as correction of behaviour in dogs  

Microsoft Academic Search

In the canine business, running from dogs kept as family pets to highly specialized working dogs, training methods are frequently discussed. One of the methods causing a consistent debate is the use of shock collars. A shock collar is an electric receiver attached to the animals' neck by a firm collar. The owner\\/trainer holds a transmitter, which can be used

Carina Kraft Thomassen

482

The domestic dog: man's best friend in the genomic era  

Microsoft Academic Search

ABSTRACT: The domestic dog genome - shaped by domestication, adaptation to human-dominated environments and artificial selection - encodes tremendous phenotypic diversity. Recent developments have improved our understanding of the genetics underlying this diversity, unleashing the dog as an important model organism for complex-trait analysis.

Adam R Boyko

2011-01-01

483

Serologic detection of Angiostrongylus vasorum infection in dogs  

Microsoft Academic Search

Angiostrongylus vasorum, French Heartworm, is a metastrongylid nematode infecting the pulmonary arteries and right heart of wild and domestic canids in various regions of the world. Infection in dogs can result in fatal cardiopulmonary disease. A single endemic focus of A. vasorum in North America occurs in the southeastern portion of Newfoundland, Canada. Dogs are currently diagnosed by detection of

I. Verzberger-Epshtein; R. J. F. Markham; J. A. Sheppard; H. Stryhn; H. Whitney; G. A. Conboy

2008-01-01

484

MITF and White Spotting in Dogs: A Population Study  

Microsoft Academic Search

This study was designed to determine if one of the variants found in our laboratory, or previously reported in microphthalmia- associated transcription factor (MITF), was associated with one or more spotting patterns in dogs. None of the rare variants found in the coding sequence consistently occurred in dogs of any particular spotting pattern. However, an insertion of a short interspersed

SHEILA M. SCHMUTZ; T. G. Berryere; DAYNA L. DREGER

2009-01-01

485

Angiostrongylus vasorum infection in 2 dogs from Newfoundland.  

PubMed

Described are the first antemortem diagnosis made via fecal examination using the Baermann technique and the first postmortem recovery of endemic Angiostrongylus vasorum in dogs from North America, specifically the Avalon peninsula of Newfoundland. In one dog, A. vasorum was recovered and identified at postmortem; gross and histologic lesions are described. PMID:12497965

Bourque, Andrea; Conboy, Gary; Miller, Lisa; Whitney, Hugh; Ralhan, Sanjay

2002-11-01

486

A novel intradural extramedullary spinal cord tumor in young dogs  

Microsoft Academic Search

We have studied an unusual, spontaneous, intradural extramedullary spinal cord tumor in 12 dogs. Animals presented with paraparesis and ataxia early in life (11\\/12 ranged from 6 to 38 months of age) suggesting that these tumors may be congenital. Various breeds of dogs were represented with four cases in German Shepherds and three in retrievers; there was no sex predisposition.

B. A. Summers; A. deLahunta; M. McEntee; F. P. Kuhajda

1988-01-01

487

Distal neuropathy in spontaneous diabetes mellitus in the dog  

Microsoft Academic Search

Peripheral nerves of three mature dogs with chronic spontaneous diabetes mellitus were examined using qualitative and quantitative techniques. The principal pathologic findings in single-teased fibers were remyelination and axonal regeneration. It is suggested that these changes which occurred in distal plantar nerves but not in more proximal tibial nerves result from a distal axonopathy. The dog may prove to be

K. G. Braund; J. E. Steiss

1982-01-01

488

Canine diabetes mellitus: can old dogs teach us new tricks?  

Microsoft Academic Search

Background  Diabetes is common in dogs, with an estimated prevalence of 0.32% in the UK. Clinical signs, as in man, include polydipsia, polyuria and weight loss, associated with hyperglycaemia and glucosuria. Diabetes typically occurs in dogs between 5 and 12 years of age, and is uncommon under 3 years of age. Breeds predisposed to diabetes include the Samoyed, Tibetan Terrier and

B. Catchpole; J. M. Ristic; L. M. Fleeman; L. J. Davison

2005-01-01

489

Canine Distemper Virus Strains Circulating among North American Dogs  

Microsoft Academic Search

Canine distemper virus (CDV) is a highly contagious virus that causes multisystemic disease in dogs. We received seven samples from dogs with CD from the United States during 2007. CDV isolates from these samples formed large, multinucleated syncytia in a Vero cell line expressing canine signaling lymphocyte activation molecule (SLAM). Based on the hemagglutinin gene sequences, the CDV isolates from

Sanjay Kapil; Robin W. Allison; Larry Johnston; Brandy L. Murray; Steven Holland; Jim Meinkoth; Bill Johnson

2008-01-01

490

Assessing fear of novel and startling stimuli in domestic dogs  

Microsoft Academic Search

Dog attacks on humans are a community issue and, while defensive and offensive aggression are implicated, little is known about the motivational basis of these attacks. Defensive aggression arising from fear may be implicated in some attacks and thus research on measuring fear in dogs is clearly required. The aim of the present study was to examine the validity of

Jacqueline Ley; Grahame J. Coleman; Robert Holmes; Paul H. Hemsworth

2007-01-01

491

Domination of olfaction over vision in explosives detection by dogs  

Microsoft Academic Search

This study examines the relative contribution of the senses of sight and smell to detection of explosives in dogs. Six sniffer dogs were required to detect explosives in a controlled (indoors) and uncontrolled (field track) environment, under both virtually dark (very low light intensity) and full light conditions. Detection percentages, search duration, and sniffing and panting frequencies were measured.Olfaction was

Irit Gazit; Joseph Terkel

2003-01-01

492

Managing Dog Waste: Campaign Insights from the Health Belief Model  

ERIC Educational Resources Information Center

Aiming to help municipalities develop effective education and outreach campaigns to reduce stormwater pollutants, such as pet waste, this study applied the Health Belief Model (HBM) to identify perceptions of dog waste and corresponding collection behaviors from dog owners living in a small U.S. city. Results of 455 online survey responses…

Typhina, Eli; Yan, Changmin

2014-01-01

493

Successful treatment of nasal sporotrichosis in a dog  

Microsoft Academic Search

Sporotrichosis is an uncommon mycosis of dogs caused by Sporothrix schenckii. This report details the diagnosis and treatment of intranasal sporotrichosis in a dog presented for a loss of smell, sneezing, and nasal congestion. Following 6 months of itraconazole treatment, a computed tomography scan showed a complete resolution of previously identified abnormalities.

Jacqueline C. Whittemore; C B Webb

2007-01-01

494

Successful treatment of nasal sporotrichosis in a dog.  

PubMed

Sporotrichosis is an uncommon mycosis of dogs caused by Sporothrix schenckii. This report details the diagnosis and treatment of intranasal sporotrichosis in a dog presented for a loss of smell, sneezing, and nasal congestion. Following 6 months of itraconazole treatment, a computed tomography scan showed a complete resolution of previously identified abnormalities. PMID:17494369

Whittemore, Jacqueline C; Webb, Craig B

2007-04-01

495

INCIDENCE OF OSTEOCHONDROSIS IN DOGS AND ITS LATE DIAGNOSIS  

Microsoft Academic Search

Neăas A., M. Dvofiák, J. Zatloukal: Incidence of Osteochondrosis in Dogs and Its Late Diagnosis. Acta Vet. Brno 1999, 68: 131-139. An incidence of osteochondrosis in dogs from the total number of 38 126 patients treated in the Clinic of Surgery and Orthopedics at University of Veterinary and Pharmaceutical Sciences in Brno from 1989 till the end of October 1998

A. NEâAS; M. DVO; J. ZATLOUKAL