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Sample records for watch gaw programme

  1. Gamma Air Watch (GAW): the electronics and trigger concept

    E-print Network

    P. Assis; G. Agnetta; P. Brogueira; O. Catalano; G. Cusumano; N. Galli; S. Giarrusso; G. la Rosa; M. Pimenta; G. Pires; F. Russo; B. Sacco

    2007-07-30

    GAW proposes a new approach for the detection and measurement of the Cherenkov light produced by GeV/TeV gamma rays traversing the Earth atmosphere which imposes specific requirements on the electronics design. The focal surface of the GAW telescope consists of a matrix of multi-anode photomultipliers. The large number of active channels (of the order of 10^5) makes it basically a large UV sensitive digital camera with high resolution imaging capability. The limited amount of space available, due to the large number of channels, requires a compact design with minimal distance between the elements of the focal surface. The front-end electronics uses the single photoelectron counting technique to capture the Cherenkov light. The data acquisition is based on free-running data taking method. Self-triggering capability for each telescope is assured by detecting an excess of active pixels, in a 10ns time frame, inside overlapping trigger areas covering the whole focal surface. In this paper we describe the GAW electronics, as well as the trigger concept and implementation.

  2. The first VOC intercomparison exercise within the Global Atmosphere Watch (GAW)

    NASA Astrophysics Data System (ADS)

    Rappenglück, B.; Apel, E.; Bauerfeind, M.; Bottenheim, J.; Brickell, P.; ?avolka, P.; Cech, J.; Gatti, L.; Hakola, H.; Honzak, J.; Junek, R.; Martin, D.; Noone, C.; Plass-Dülmer, Ch.; Travers, D.; Wang, D.

    In 2003 the World Calibration Centre for volatile organic compounds (WCC-VOC) which forms part of the Global Atmosphere Watch (GAW) program coordinated the first comprehensive intercomparison exercise among the GAW-VOC community. The intercomparison focused on a synthetic C 2-C 11 VOC standard mixture in nitrogen (N 2) and involved nine different stations/laboratories (10 instruments) from seven countries (Brazil, Canada [two labs], Czech Republic, Finland, Germany [two labs; three instruments], Ireland, and Slovakia), representing four measurement programs (GAW, EMEP, CAPMoN, LBA). These sites either run canister or online measurements. WCC-VOC provided each participant of the intercomparison exercise with standard gas canisters which contained 73 VOCs prepared and certified by the National Center for Atmospheric Research (NCAR), Boulder. The participating laboratories were expected to identify and quantify as many compounds of the WCC-VOC standard canister as possible based on their routine identification and calibration methods. The primary objective of this first intercomparison was to examine the current performance status of the analytical facilities of each laboratory and to check whether the results meet the Data Quality Objectives (DQO) developed by WCC-VOC. An additional objective was to establish a ranking of properly determined compounds among all laboratories in order to identify compounds which could be most accurately determined by all laboratories. Due to the variety of sampling and analytical methods among the participants both the number of identified species (16-150 VOCs) and their proper quantification differed largely. Focusing on a subset of 28 VOCs recognized as primary GAW target compounds the results show that the DQOs for repeatability are met in most cases. However for the deviation from the WCC-VOC reference values the picture is different. For some VOCs the concentrations differed significantly among the different laboratories. In terms of both uncertainty and repeatability a significant number of atmospherically relevant VOCs (e.g. propane, propylene, isoprene, and benzene) are properly determined by most labs. However, difficulties occur with other important VOCs (e.g. acetylene, i-pentane, toluene). From this subset of VOC results it appears imperative to strengthen harmonization procedures particular with regard to real air samplings. These processes have been initiated and include more frequent intercomparisons also covering ambient air samples, individual performance audits, and a future networkwide calibration standard.

  3. Long-term observations of tropospheric ozone: GAW Measurement Guidelines

    NASA Astrophysics Data System (ADS)

    Tarasova, Oksana; Galbally, Ian E.; Schultz, Martin G.

    2013-04-01

    The Global Atmosphere Watch (GAW) Programme of the World Meteorological Organization (WMO) coordinates long-term observations of the chemical composition and physical properties of the atmosphere which are relevant for understanding of atmospheric chemistry and climate change. Atmospheric observations of reactive gases (tropospheric ozone, carbon monoxide, volatile organic compounds and nitrogen oxides) coordinated by the GAW Programme complement local and regional scale air quality monitoring efforts. As part of the GAW quality assurance (QA) system detailed measurement guidelines for atmospheric trace species are developed by international expert teams at irregular intervals. The most recent report focuses on continuous in-situ measurements of ozone in the troposphere, performed in particular at continental or island sites with altitudes ranging from sea level to mountain tops. Data Quality Objectives (DQOs) are defined for different applications of the data (e.g. trend analysis and verification of global model forecasts). These DQOs include a thorough discussion of the tolerable level of measurement uncertainty and data completeness. The guidelines present the best practices and practical arrangements adopted by the GAW Programme in order to enable the GAW station network to approach or achieve the defined tropospheric ozone DQOs. The document includes information on the selection of station and measurement locations, required skills and training of staff, recommendations on the measurement technique and the necessary equipment to perform highest quality measurements, rules for conducting the measurements, preparing the data and archiving them, and more. Much emphasis is given to discussions about how to ensure the quality of the data through tracing calibrations back to primary standards, proper calibration and data analysis, etc. In the GAW Programme the QA system is implemented through Central Facilities (Central Calibration Laboratories, World and Regional Calibration Centers and World Data Centers), Scientific Advisory Groups and GAW Training and Education Center. These bodies support primary standards, provide calibration and data archiving facilities, coordinate comparison campaigns, perform stations audit, provide documentation and training of personnel.

  4. The PharmWatch programme: challenges to engaging the community pharmacists in Jamaica

    PubMed Central

    Gossell-Williams, Maxine; Adebayo, Sarafadeen A.

    2008-01-01

    In February 2006, there was a renewed effort to encourage reporting of adverse drug reactions (ADRs) in Jamaica. It involved renaming the process the “PharmWatchprogramme and revising the reporting form. Objectives The aims of this study were to assess the attitudes of community pharmacists to ADR reporting and to assess their utilization of the PharmWatch programme. Methods The survey was conducted in January 2007, involving 102 community pharmacists islandwide. A questionnaire was designed to assess their attitudes towards ADR reporting, their awareness of the PharmWatch programme and also to collate number of ADRs through recall. Pharmacists were then followed prospectively to collect ADRs occurring over the next three months using the PharmWatch form. Results Although most of the pharmacists involved in the survey had more than five years of experience, the majority (67%) were not aware of the PharmWatch programme; however, 86% of the responding pharmacists indicated that they accepted that ADR reporting was a professional responsibility. They identified “reaction already known”, “more information needed about reporting ADRs” and “lack of time” as key factors that would cause non-reporting. One hundred and twenty eight retrospective ADRs were collected; none were reported to the Ministry of Health directly, while two were reported to the respective drug companies. A three month prospective follow-up with pharmacists yielded 45 reports. The most common ADR reports among both the retrospective and prospective data were associated with anti-infectives. Conclusions The results suggest that awareness of the PharmWatch programme is not adequate to facilitate active participation in ADR reporting. More proactive interventions, such as continuous training and encouragement in the use of ADR reporting should be considered. PMID:25157292

  5. Results of a feasibility randomised controlled trial (RCT) for WATCH IT: a programme for obese children and adolescents

    PubMed Central

    Farrin, Amanda; Christie, Deborah; Jebb, Susan A; Cooper, Ashley R; Rudolf, Mary

    2011-01-01

    Background In the evaluation of childhood obesity interventions, few researchers undertake a rigorous feasibility stage in which the design and procedures of the evaluation process are examined. Consequently, phase III studies often demonstrate methodological weaknesses. Purpose Our aim was to conduct a feasibility trial of the evaluation of WATCH IT, a community obesity intervention for children and adolescents. We sought to determine an achievable recruitment rate; acceptability of randomisation, assessment procedures, and dropout rate; optimal outcome measures for the definitive trial; and a robust sample size calculation. Method Our goal was to recruit 70 participants over 6 months, randomise them to intervention or control group, and retain participation for 12 months. Assessments were taken prior to randomisation and after 6 and 12 months. Procedures mirrored those intended for a full-scale trial, but multiple measures of similar outcomes were included as a means to determine those most appropriate for future research. Acceptability of the research and impact of the research on the programme were ascertained through interviewing participants and staff. Results We recruited 70 participants and found that randomisation and data collection procedures were acceptable. Self-referral (via media promotion) was more effective than professional referral. Blinding of assessors was sustained to a reasonable degree, and optimal outcome measures for a full-scale trial were identified. Estimated sample size was significantly greater than sample sized reported in published trials. There was some negative impact on the existing programme as a result of the research, a lesson for designers of future trials. Limitations We successfully recruited socially disadvantaged families, but the majority of families were of White British nationality. The composition of the participants was an added valuable lesson, suggesting that recruitment strategies to obtain a more heterogeneous ethnic sample warrant consideration in future research. Conclusions This study provided us with confidence that we can run a phase III multi-centre trial to test the effectiveness of WATCH IT. Importantly, it was invaluable in informing the design not only of that trial but also of future evaluations of childhood obesity treatment interventions. PMID:22024104

  6. A statistical approach to quantify uncertainty in carbon monoxide measurements at the Izaña global GAW station: 2008-2011

    NASA Astrophysics Data System (ADS)

    Gomez-Pelaez, A. J.; Ramos, R.; Gomez-Trueba, V.; Novelli, P. C.; Campo-Hernandez, R.

    2013-03-01

    Atmospheric CO in situ measurements are carried out at the Izaña (Tenerife) global GAW (Global Atmosphere Watch Programme of the World Meteorological Organization - WMO) mountain station using a Reduction Gas Analyser (RGA). In situ measurements at Izaña are representative of the subtropical Northeast Atlantic free troposphere, especially during nighttime. We present the measurement system configuration, the response function, the calibration scheme, the data processing, the Izaña 2008-2011 CO nocturnal time series, and the mean diurnal cycle by months. We have developed a rigorous uncertainty analysis for carbon monoxide measurements carried out at the Izaña station, which could be applied to other GAW stations. We determine the combined standard measurement uncertainty taking into consideration four contributing components: uncertainty of the WMO standard gases interpolated over the range of measurement, the uncertainty that takes into account the agreement between the standard gases and the response function used, the uncertainty due to the repeatability of the injections, and the propagated uncertainty related to the temporal consistency of the response function parameters (which also takes into account the covariance between the parameters). The mean value of the combined standard uncertainty decreased significantly after March 2009, from 2.37 nmol mol-1 to 1.66 nmol mol-1, due to improvements in the measurement system. A fifth type of uncertainty we call representation uncertainty is considered when some of the data necessary to compute the temporal mean are absent. Any computed mean has also a propagated uncertainty arising from the uncertainties of the data used to compute the mean. The law of propagation depends on the type of uncertainty component (random or systematic). In situ hourly means are compared with simultaneous and collocated NOAA flask samples. The uncertainty of the differences is computed and used to determine whether the differences are significant. For 2009-2011, only 24.5% of the differences are significant, and 68% of the differences are between -2.39 and 2.5 nmol mol-1. Total and annual mean differences are computed using conventional expressions but also expressions with weights based on the minimum variance method. The annual mean differences for 2009-2011 are well within the ±2 nmol mol-1 compatibility goal of GAW.

  7. ACTRIS non-methane hydrocarbon intercomparison experiment in Europe to support WMO GAW and EMEP observation networks

    NASA Astrophysics Data System (ADS)

    Hoerger, C. C.; Claude, A.; Plass-Duelmer, C.; Reimann, S.; Eckart, E.; Steinbrecher, R.; Aalto, J.; Arduini, J.; Bonnaire, N.; Cape, J. N.; Colomb, A.; Connolly, R.; Diskova, J.; Dumitrean, P.; Ehlers, C.; Gros, V.; Hakola, H.; Hill, M.; Hopkins, J. R.; Jäger, J.; Junek, R.; Kajos, M. K.; Klemp, D.; Leuchner, M.; Lewis, A. C.; Locoge, N.; Maione, M.; Martin, D.; Michl, K.; Nemitz, E.; O'Doherty, S.; Pérez Ballesta, P.; Ruuskanen, T. M.; Sauvage, S.; Schmidbauer, N.; Spain, T. G.; Straube, E.; Vana, M.; Vollmer, M. K.; Wegener, R.; Wenger, A.

    2015-07-01

    The performance of 18 European institutions involved in long-term non-methane hydrocarbon (NMHC) measurements in ambient air within the framework of the Global Atmosphere Watch (GAW) and the European Monitoring and Evaluation Programme (EMEP) was assessed with respect to data quality objectives (DQOs) of ACTRIS (Aerosols, Clouds, and Trace gases Research InfraStructure Network) and GAW. Compared to previous intercomparison studies the DQOs define a novel approach to assess and ensure a high quality of the measurements. Having already been adopted by GAW, the ACTRIS DQOs are demanding with deviations to a reference value of less than 5 % and a repeatability of better than 2 % for NMHC mole fractions above 0.1 nmol mol-1. The participants of the intercomparison analysed two dry gas mixtures in pressurised cylinders, a 30-component NMHC mixture in nitrogen (NMHC_N2) at approximately 1 nmol mol-1 and a whole air sample (NMHC_air), following a standardised operation procedure including zero- and calibration gas measurements. Furthermore, participants had to report details on their instruments and assess their measurement uncertainties. The NMHCs were analysed either by gas chromatography-flame ionisation detection (GC-FID) or by gas chromatography-mass spectrometry (GC-MS). For the NMHC_N2 measurements, 62 % of the reported values were within the 5 % deviation class corresponding to the ACTRIS DQOs. For NMHC_air, generally more frequent and larger deviations to the assigned values were observed, with 50 % of the reported values within the 5 % deviation class. Important contributors to the poorer performance in NMHC_air compared to NMHC_N2 were a more complex matrix and a larger span of NMHC mole fractions (0.03-2.5 nmol mol-1). The performance of the participating laboratories were affected by the different measurement procedures such as the usage of a two-step vs. a one-step calibration, breakthroughs of C2-C3 hydrocarbons in the focussing trap, blank values in zero-gas measurements (especially for those systems using a Nafion® Dryer), adsorptive losses of aromatic compounds, and insufficient chromatographic separation.

  8. The sensitivity of mussel-watch programmes to detect temporal trends in the bio-availability of metals. A case study of the Saronicos Gulf of Greece.

    PubMed

    Zangrandi, Marco; Catsiki, Vassiliki-Angelique; Avdis, Olivia L V

    2005-08-01

    Statistical power analysis has been used to determine the sensitivity of the mussel-watch programme in Hellenic seas, with particular focus placed on the data obtained for metal content in mussels from the Saronicos Gulf during the period 1985-1997. Sample collection was carried out quarterly. Soft tissues of 60-100 similarly sized mussels (Mytilus galloprovincialis) were pooled into six composite samples and analysed by Atomic Absorption Spectroscopy (AAS). The study concludes that the resolution of monitoring programmes employed thus far is sufficiently high to detect temporal trends related to changes in contaminant levels caused either by drastic environmental control (such as those imposed on point-source pollutants) or by sudden increases in contaminant load. However, the detection of more subtle trends, which may be expected in the near future as a result of global pollution-control policies, is likely to require the adoption of much more sensitive programmes. In addition, the review of up-to-date knowledge on metal biology in mussels suggests that factors related to growth and reproduction should be taken into account to remarkably increase the resolution of mussel-watch programmes. Indicative maximum values for components of error to be complied with during routine monitoring are suggested. PMID:16049581

  9. Terpenoids from the Octocoral Sinularia gaweli

    PubMed Central

    Lin, Wun-Jie; Wu, Tung-Ying; Su, Tzu-Rong; Wen, Zhi-Hong; Chen, Jih-Jung; Fang, Lee-Shing; Wu, Yang-Chang; Sung, Ping-Jyun

    2015-01-01

    Two eudesmane sesquiterpenoids, verticillatol (1) and 5?-acetoxy-4(14)-eudesmene-1?-ol (2) and two cembrane diterpenoids, (–)-leptodiol acetate (3) and sinulacembranolide A (4) were isolated from the octocoral Sinularia gaweli and compounds 2–4 are new isolates. The structures of new terpenoids 2–4 were elucidated by spectroscopic methods and by comparison the spectral data with those of known analogues. Terpenoid 4 was found to inhibit the accumulation of the pro-inflammatory inducible nitric oxide synthase (iNOS) protein of the lipopolysaccharide (LPS)-stimulated RAW264.7 marcophage cells. PMID:26295226

  10. Television watching

    MedlinePLUS

    ... normally. Watching television may take the place of social interaction with friends and family. Children who watch too ... time, and other times of the day when social interaction and learning are going on. Read to -- and ...

  11. Metadata for WIS and WIGOS: GAW Profile of ISO19115 and Draft WIGOS Core Metadata Standard

    NASA Astrophysics Data System (ADS)

    Klausen, Jörg; Howe, Brian

    2014-05-01

    The World Meteorological Organization (WMO) Integrated Global Observing System (WIGOS) is a key WMO priority to underpin all WMO Programs and new initiatives such as the Global Framework for Climate Services (GFCS). The development of the WIGOS Operational Information Resource (WIR) is central to the WIGOS Framework Implementation Plan (WIGOS-IP). The WIR shall provide information on WIGOS and its observing components, as well as requirements of WMO application areas. An important aspect is the description of the observational capabilities by way of structured metadata. The Global Atmosphere Watch is the WMO program addressing the chemical composition and selected physical properties of the atmosphere. Observational data are collected and archived by GAW World Data Centres (WDCs) and related data centres. The Task Team on GAW WDCs (ET-WDC) have developed a profile of the ISO19115 metadata standard that is compliant with the WMO Information System (WIS) specification for the WMO Core Metadata Profile v1.3. This profile is intended to harmonize certain aspects of the documentation of observations as well as the interoperability of the WDCs. The Inter-Commission-Group on WIGOS (ICG-WIGOS) has established the Task Team on WIGOS Metadata (TT-WMD) with representation of all WMO Technical Commissions and the objective to define the WIGOS Core Metadata. The result of this effort is a draft semantic standard comprising of a set of metadata classes that are considered to be of critical importance for the interpretation of observations relevant to WIGOS. The purpose of the presentation is to acquaint the audience with the standard and to solicit informal feed-back from experts in the various disciplines of meteorology and climatology. This feed-back will help ET-WDC and TT-WMD to refine the GAW metadata profile and the draft WIGOS metadata standard, thereby increasing their utility and acceptance.

  12. Password Management Strategies for Online Accounts Shirley Gaw

    E-print Network

    Sadeh, Norman M.

    Password Management Strategies for Online Accounts Shirley Gaw Department of Computer Science authentication in on- line correspondence, subscription services, and shopping, there is growing concern about justified their habits. While they wanted to protect financial data and personal communication, reusing

  13. Identifying rare variants from exome scans: the GAW17 experience

    PubMed Central

    2011-01-01

    Genetic Analysis Workshop 17 (GAW17) provided a platform for evaluating existing statistical genetic methods and for developing novel methods to analyze rare variants that modulate complex traits. In this article, we present an overview of the 1000 Genomes Project exome data and simulated phenotype data that were distributed to GAW17 participants for analyses, the different issues addressed by the participants, and the process of preparation of manuscripts resulting from the discussions during the workshop. PMID:22373325

  14. Trial watch

    PubMed Central

    Menger, Laurie; Vacchelli, Erika; Kepp, Oliver; Eggermont, Alexander; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Cardiac glycosides (CGs) are natural compounds sharing the ability to operate as potent inhibitors of the plasma membrane Na+/K+-ATPase, hence promoting—via an indirect mechanism—the intracellular accumulation of Ca2+ ions. In cardiomyocytes, increased intracellular Ca2+ concentrations exert prominent positive inotropic effects, that is, they increase myocardial contractility. Owing to this feature, two CGs, namely digoxin and digitoxin, have extensively been used in the past for the treatment of several cardiac conditions, including distinct types of arrhythmia as well as contractility disorders. Nowadays, digoxin is approved by the FDA and indicated for the treatment of congestive heart failure, atrial fibrillation and atrial flutter with rapid ventricular response, whereas the use of digitoxin has been discontinued in several Western countries. Recently, CGs have been suggested to exert potent antineoplastic effects, notably as they appear to increase the immunogenicity of dying cancer cells. In this Trial Watch, we summarize the mechanisms that underpin the unsuspected anticancer potential of CGs and discuss the progress of clinical studies that have evaluated/are evaluating the safety and efficacy of CGs for oncological indications. PMID:23525565

  15. Trial watch

    PubMed Central

    Vacchelli, Erika; Galluzzi, Lorenzo; Eggermont, Alexander; Fridman, Wolf Hervé; Galon, Jerome; Sautès-Fridman, Catherine; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido

    2012-01-01

    Toll-like receptors (TLRs) have first been characterized for their capacity to detect conserved microbial components like lipopolysaccharide (LPS) and double-stranded RNA, resulting in the elicitation of potent (innate) immune responses against invading pathogens. More recently, TLRs have also been shown to promote the activation of the cognate immune system against cancer cells. Today, only three TLR agonists are approved by FDA for use in humans: the bacillus Calmette-Guérin (BCG), monophosphoryl lipid A (MPL) and imiquimod. BCG (an attenuated strain of Mycobacterium bovis) is mainly used as a vaccine against tuberculosis, but also for the immunotherapy of in situ bladder carcinoma. MPL (derived from the LPS of Salmonella minnesota) is included in the formulation of Cervarix®, a vaccine against human papillomavirus-16 and -18. Imiquimod (a synthetic imidazoquinoline) is routinely employed for actinic keratosis, superficial basal cell carcinoma, and external genital warts (condylomata acuminata). In this Trial Watch, we will summarize the results of recently completed clinical trials and discuss the progress of ongoing studies that have evaluated/are evaluating FDA-approved TLR agonists as off-label medications for cancer therapy. PMID:23162757

  16. Trial Watch

    PubMed Central

    Galluzzi, Lorenzo; Vacchelli, Erika; Fridman, Wolf Hervé; Galon, Jerome; Sautès-Fridman, Catherine; Tartour, Eric; Zucman-Rossi, Jessica; Zitvogel, Laurence; Kroemer, Guido

    2012-01-01

    Since the advent of hybridoma technology, dating back to 1975, monoclonal antibodies have become an irreplaceable diagnostic and therapeutic tool for a wide array of human diseases. During the last 15 years, several monoclonal antibodies (mAbs) have been approved by FDA for cancer therapy. These mAbs are designed to (1) activate the immune system against tumor cells, (2) inhibit cancer cell-intrinsic signaling pathways, (3) bring toxins in the close proximity of cancer cells, or (4) interfere with the tumor-stroma interaction. More recently, major efforts have been made for the development of immunostimulatory mAbs that either enhance cancer-directed immune responses or limit tumor- (or therapy-) driven immunosuppression. Some of these antibodies, which are thought to facilitate tumor eradication by initiating or sustaining a tumor-specific immune response, have already entered clinical trials. In this Trial Watch, we will review and discuss the clinical progress of the most important mAbs that are have entered clinical trials after January 2008. PMID:22720209

  17. Trial Watch

    PubMed Central

    Vacchelli, Erika; Aranda, Fernando; Eggermont, Alexander; Galon, Jérôme; Sautès-Fridman, Catherine; Cremer, Isabelle; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    Accumulating evidence suggests that the clinical efficacy of selected anticancer drugs, including conventional chemotherapeutics as well as targeted anticancer agents, originates (at least in part) from their ability to elicit a novel or reinstate a pre-existing tumor-specific immune response. One of the mechanisms whereby chemotherapy can stimulate the immune system to recognize and destroy malignant cells is commonly known as immunogenic cell death (ICD). Cancer cells succumbing to ICD are de facto converted into an anticancer vaccine and as such elicit an adaptive immune response. Several common chemotherapeutics share the ability of triggering ICD, as demonstrated in vaccination experiments relying on immunocompetent mice and syngeneic cancer cells. A large number of ongoing clinical trials involve such ICD inducers, often (but not always) as they are part of the gold standard therapeutic approach against specific neoplasms. In this Trial Watch, we summarize the latest advances on the use of cyclophosphamide, doxorubicin, epirubicin, oxaliplatin, and mitoxantrone in cancer patients, discussing high-impact studies that have been published during the last 13 months as well as clinical trials that have been initiated in the same period to assess the antineoplastic profile of these immunogenic drugs as off-label therapeutic interventions. PMID:24800173

  18. Trial Watch

    PubMed Central

    Aranda, Fernando; Vacchelli, Erika; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Hervé Fridman, Wolf; Cremer, Isabelle; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    The expression “adoptive cell transfer” (ACT) is commonly employed to indicate an immunotherapeutic regimen involving the isolation of autologous blood-borne or tumor-infiltrating lymphocytes, their selection/expansion/activation ex vivo, and their reinfusion into the patient, most often in the context of lymphodepleting pre-conditioning and in combination with immunostimulatory treatments. Optionally, the cellular material for ACT is genetically manipulated before expansion to (1) target specific tumor-associated antigens; (2) endogenously express immunostimulatory molecules; and/or (3) persist for long periods upon reinfusion. Consistent efforts have been dedicated at the amelioration of this immunotherapeutic regimen throughout the past decade, resulting in the establishment of ever more efficient and safer ACT protocols. Accordingly, the number of clinical trials testing ACT in oncological indications does not cease to increase. In this Trial Watch, we summarize recent developments in this exciting area of research, covering both high-impact studies that have been published during the last 12 months and clinical trials that have been launched in the same period to evaluate the safety and therapeutic potential of ACT in cancer patients. PMID:25050207

  19. Trial Watch

    PubMed Central

    Pol, Jonathan; Bloy, Norma; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Hervé Fridman, Wolf; Cremer, Isabelle; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    During the past 2 decades, the possibility that preparations capable of eliciting tumor-specific immune responses would mediate robust therapeutic effects in cancer patients has received renovated interest. In this context, several approaches to vaccinate cancer patients against their own malignancies have been conceived, including the administration of DNA constructs coding for one or more tumor-associated antigens (TAAs). Such DNA-based vaccines conceptually differ from other types of gene therapy in that they are not devised to directly kill cancer cells or sensitize them to the cytotoxic activity of a drug, but rather to elicit a tumor-specific immune response. In spite of an intense wave of preclinical development, the introduction of this immunotherapeutic paradigm into the clinical practice is facing difficulties. Indeed, while most DNA-based anticancer vaccines are well tolerated by cancer patients, they often fail to generate therapeutically relevant clinical responses. In this Trial Watch, we discuss the latest advances on the use of DNA-based vaccines in cancer therapy, discussing the literature that has been produced around this topic during the last 13 months as well as clinical studies that have been launched in the same time frame to assess the actual therapeutic potential of this intervention. PMID:24800178

  20. Trial Watch

    PubMed Central

    Aranda, Fernando; Vacchelli, Erika; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Sautès-Fridman, Catherine; Cremer, Isabelle; Henrik ter Meulen, Jan; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    Toll-like receptors (TLRs) are an evolutionarily conserved group of enzymatically inactive, single membrane-spanning proteins that recognize a wide panel of exogenous and endogenous danger signals. Besides constituting a crucial component of the innate immune response to bacterial and viral pathogens, TLRs appear to play a major role in anticancer immunosurveillance. In line with this notion, several natural and synthetic TLR ligands have been intensively investigated for their ability to boost tumor-targeting immune responses elicited by a variety of immunotherapeutic and chemotherapeutic interventions. Three of these agents are currently approved by the US Food and Drug Administration (FDA) or equivalent regulatory agencies for use in cancer patients: the so-called bacillus Calmette-Guérin, monophosphoryl lipid A, and imiquimod. However, the number of clinical trials testing the therapeutic potential of both FDA-approved and experimental TLR agonists in cancer patients is stably decreasing, suggesting that drug developers and oncologists are refocusing their interest on alternative immunostimulatory agents. Here, we summarize recent findings on the use of TLR agonists in cancer patients and discuss how the clinical evaluation of FDA-approved and experimental TLR ligands has evolved since the publication of our first Trial Watch dealing with this topic. PMID:25083332

  1. Trial watch

    PubMed Central

    Vacchelli, Erika; Vitale, Ilio; Eggermont, Alexander; Fridman, Wolf Hervé; Fu?íková, Jitka; Cremer, Isabelle; Galon, Jérôme; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Dendritic cells (DCs) occupy a privileged position at the interface between innate and adaptive immunity, orchestrating a large panel of responses to both physiological and pathological cues. In particular, whereas the presentation of antigens by immature DCs generally results in the development of immunological tolerance, mature DCs are capable of priming robust, and hence therapeutically relevant, adaptive immune responses. In line with this notion, functional defects in the DC compartment have been shown to etiologically contribute to pathological conditions including (but perhaps not limited to) infectious diseases, allergic and autoimmune disorders, graft rejection and cancer. Thus, the possibility of harnessing the elevated immunological potential of DCs for anticancer therapy has attracted considerable interest from both researchers and clinicians over the last decade. Alongside, several methods have been developed not only to isolate DCs from cancer patients, expand them, load them with tumor-associated antigens and hence generate highly immunogenic clinical grade infusion products, but also to directly target DCs in vivo. This intense experimental effort has culminated in 2010 with the approval by the US FDA of a DC-based preparation (sipuleucel-T, Provenge®) for the treatment of asymptomatic or minimally symptomatic metastatic castration-refractory prostate cancer. As an update to the latest Trial Watch dealing with this exciting field of research (October 2012), here we summarize recent advances in DC-based anticancer regimens, covering both high-impact studies that have been published during the last 13 mo and clinical trials that have been launched in the same period to assess the antineoplastic potential of this variant of cellular immunotherapy. PMID:24286020

  2. Trial Watch

    PubMed Central

    Vacchelli, Erika; Eggermont, Alexander; Fridman, Wolf Hervé; Galon, Jérôme; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Adoptive cell transfer (ACT) represents a prominent form of immunotherapy against malignant diseases. ACT is conceptually distinct from dendritic cell-based approaches (which de facto constitute cellular vaccines) and allogeneic transplantation (which can be employed for the therapy of hematopoietic tumors) as it involves the isolation of autologous lymphocytes exhibiting antitumor activity, their expansion/activation ex vivo and their reintroduction into the patient. Re-infusion is most often performed in the context of lymphodepleting regimens (to minimize immunosuppression by host cells) and combined with immunostimulatory interventions, such as the administration of Toll-like receptor agonists. Autologous cells that are suitable for ACT protocols can be isolated from tumor-infiltrating lymphocytes or generated by engineering their circulating counterparts for the expression of transgenic tumor-specific T-cell receptors. Importantly, lymphocytes can be genetically modified prior to re-infusion for increasing their persistence in vivo, boosting antitumor responses and minimizing side effects. Moreover, recent data indicate that exhausted antitumor T lymphocytes may be rejuvenated in vitro by exposing them to specific cytokine cocktails, a strategy that might considerably improve the clinical success of ACT. Following up the Trial Watch that we published on this topic in the third issue of OncoImmunology (May 2012), here we summarize the latest developments in ACT-related research, covering both high-impact studies that have been published during the last 13 months and clinical trials that have been initiated in the same period to assess the antineoplastic profile of this form of cellular immunotherapy. PMID:23762803

  3. Trial watch

    PubMed Central

    Senovilla, Laura; Vacchelli, Erika; Garcia, Pauline; Eggermont, Alexander; Fridman, Wolf Hervé; Galon, Jérôme; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    The foundation of modern vaccinology dates back to the 1790s, when the English physician Edward Jenner uncovered the tremendous medical potential of prophylactic vaccination. Jenner’s work ignited a wave of nationwide vaccination campaigns abating the incidence of multiple life-threatening infectious diseases and culminating with the eradication of natural smallpox virus, which was definitively certified by the WHO in 1980. The possibility of using vaccines against cancer was first proposed at the end of the 19th century by Paul Ehrlich and William Coley. However, it was not until the 1990s that such a hypothesis began to be intensively investigated, following the realization that the immune system is not completely unresponsive to tumors and that neoplastic cells express immunogenic tumor-associated antigens (TAAs). Nowadays, anticancer vaccines are rapidly moving from the bench to the bedside, and a few prophylactic and therapeutic preparations have already been approved by FDA for use in humans. In this setting, one interesting approach is constituted by DNA vaccines, i.e., TAA-encoding circularized DNA constructs, often of bacterial origin, that are delivered to patients as such or by means of specific vectors, including (but not limited to) liposomal preparations, nanoparticles, bacteria and viruses. The administration of DNA vaccines is most often performed via the intramuscular or subcutaneous route and is expected to cause (1) the endogenous synthesis of the TAA by myocytes and/or resident antigen-presenting cells; (2) the presentation of TAA-derived peptides on the cell surface, in association with MHC class I molecules; and (3) the activation of potentially therapeutic tumor-specific immune responses. In this Trial Watch, we will summarize the results of recent clinical trials that have evaluated/are evaluating DNA vaccines as therapeutic interventions against cancer. PMID:23734328

  4. Trial watch

    PubMed Central

    Vacchelli, Erika; Eggermont, Alexander; Sautès-Fridman, Catherine; Galon, Jérôme; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Oncolytic virotherapy is emerging as a promising approach for the treatment of several neoplasms. The term “oncolytic viruses” is generally employed to indicate naturally occurring or genetically engineered attenuated viral particles that cause the demise of malignant cells while sparing their non-transformed counterparts. From a conceptual standpoint, oncolytic viruses differ from so-called “oncotropic viruses” in that only the former are able to kill cancer cells, even though both display a preferential tropism for malignant tissues. Of note, such a specificity can originate at several different steps of the viral cycle, including the entry of virions (transductional specificity) as well as their intracellular survival and replication (post-transcriptional and transcriptional specificity). During the past two decades, a large array of replication-competent and replication-incompetent oncolytic viruses has been developed and engineered to express gene products that would specifically promote the death of infected (cancer) cells. However, contrarily to long-standing beliefs, the antineoplastic activity of oncolytic viruses is not a mere consequence of the cytopathic effect, i.e., the lethal outcome of an intense, productive viral infection, but rather involves the elicitation of an antitumor immune response. In line with this notion, oncolytic viruses genetically modified to drive the local production of immunostimulatory cytokines exert more robust therapeutic effects than their non-engineered counterparts. Moreover, the efficacy of oncolytic virotherapy is significantly improved by some extent of initial immunosuppression (facilitating viral replication and spread) followed by the administration of immunostimulatory molecules (boosting antitumor immune responses). In this Trial Watch, we will discuss the results of recent clinical trials that have evaluated/are evaluating the safety and antineoplastic potential of oncolytic virotherapy. PMID:23894720

  5. Can Positive Matrix Factorization identify sources of organic trace gases at the continental GAW site Hohenpeissenberg?

    NASA Astrophysics Data System (ADS)

    Leuchner, M.; Gubo, S.; Schunk, C.; Wastl, C.; Kirchner, M.; Menzel, A.; Plass-Dülmer, C.

    2014-03-01

    From the rural Global Atmosphere Watch (GAW) site Hohenpeissenberg in the pre-alpine area of Southern Germany, a dataset of 24 C2-C8 non-methane hydrocarbons over a period of seven years was analyzed. Receptor modeling was performed by Positive Matrix Factorization (PMF) and the resulting factors were compared to literature source profiles. Photochemical aging during transport to the relatively remote site violates the PMF prerequisite of mass conservation from source to receptor. However, previous studies showed plausible results with this method at remote sites; the applicability and restrictions of the PMF model to such a remote dataset and the influence of photochemical processing on the interpretability of the results are discussed. A six factor solution showed a high stability and the most plausible results. In addition to biogenic sources and remote sources of very stable compounds - reflecting the continental background - four additional anthropogenic factors were resolved that could be divided into two short- and two long-lived patterns from evaporative sources and incomplete combustion processes, respectively. A method to increase the uncertainty for each individual compound by including photochemical reactivity did not improve the results, but decreased the stability of the model output. The contribution of the different source categories at the site over the entire period was, in decreasing order: remote sources, long-lived evaporative sources, residential heating and long-lived combustion sources, short-lived evaporative sources, short-lived combustion sources, and biogenic sources. Despite a low overall impact, biogenic sources played an important role during summer, in particular in terms of reactivity.

  6. YELLOWSTONE RIVER WATCH (YRW)

    EPA Science Inventory

    Yellowstone River Watch seeks to expand its monitoring and education efforts throughout the Yellowstone River Basin by actively recruiting and training new teacher members. Yellowstone River Watch also seeks to advance existing school programs by offering quality assurance/quali...

  7. Swatch Watch in School

    ERIC Educational Resources Information Center

    Osterer, Irv

    2010-01-01

    For centuries, Swiss firms manufactured and sold precision watches and were the undisputed leaders in timekeeping. All this came to an abrupt end when, in the mid-1970s, the Japanese began to make reliable digital watches at a fraction of the cost of the expensive, labor-intensive Swiss product. In 1983, Switzerland answered with the introduction…

  8. Boise Watershed Watch

    USGS Multimedia Gallery

    USGS hydrologic technicians Erin Murray (far left) and Russ Miller collect water-quality data from the Boise River with citizen volunteers as part of the 2014 Boise Watershed Watch. Watershed Watch is an annual community outreach effort of the City of Boise's WaterShed Environmental Education Center...

  9. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Groover, Richard S.

    1981-01-01

    Operation Waste Watch is a seven-unit program for grades K-6 which addresses such topics as litter control, recycling, and resources recovery. It is designed to instill in students positive feelings about the environment. (DS)

  10. Treasure Valley Watershed Watch

    USGS Multimedia Gallery

    USGS biologist Dorene MacCoy and a group of citizen volunteers prepare to collect and record water-quality data as part of the October 27 Watershed Watch citizen science event on the Boise River in Boise, ID....

  11. Treasure Valley Watershed Watch

    USGS Multimedia Gallery

    USGS biologist Dorene MacCoy and a group of citizen volunteers collect and record water-quality data as part of the October 27 Watershed Watch citizen science event on the Boise River in Boise, ID....

  12. One-year aerosol profiling with EUCAARI Raman lidar at Shangdianzi GAW station: Beijing plume and seasonal variations

    NASA Astrophysics Data System (ADS)

    HäNel, A.; Baars, H.; Althausen, D.; Ansmann, A.; Engelmann, R.; Sun, J. Y.

    2012-07-01

    The study examines seasonal and air-flow-dependent variations of the vertical distribution of aerosols at the Global Atmospheric Watch (GAW) station of Shangdianzi in the North China Plain 100 km northeast of Beijing. One-year Raman lidar observations of profiles of aerosol extinction and backscatter coefficients at 532 nm were performed from April 2009 to March 2010 in the framework of the European Aerosol Cloud Climate and Air Quality Interactions (EUCAARI) project. In the nighttime statistics a two-layer structure with the main haze layer reaching to 1-1.5 km height asl and an elevated aerosol layer on top with a top height of 2.5-5 km height asl was generally observed. A case study of a Beijing haze plume is presented to document the drastic changes in the environmental conditions over the background monitoring station during the passage of a strong haze front. Aerosol optical depth (AOD) and extinction coefficients increased from 0.2 to 1.2 and from 200 Mm-1 to 1000 Mm-1, respectively, within less than two hours. The statistical analysis revealed layer mean extinction coefficients of the haze layer most frequently from 200-600 Mm-1 and typically from 50-100 Mm-1in the elevated layer. The AOD ranged from about 0.3 for northerly air flows to, on average, 0.95 during southerly air flows. The lidar ratio shows a narrow distribution peaking at 60 sr in the haze layer caused by anthropogenic fine-mode aerosol and a broad distribution from 40-90 sr in the elevated layer caused by the complex mixture of aged desert dust, biomass burning smoke, and industrial pollution over eastern Asia.

  13. Study of the regional CO2 mole fractions filtering approach at a WMO/GAW regional station in China

    NASA Astrophysics Data System (ADS)

    Fang, S. X.; Tans, P. P.; Steinbacher, M.; Zhou, L. X.; Luan, T.

    2015-07-01

    The identification of atmospheric CO2 observation data which is minimally influenced by very local emissions/removals is essential for the estimation of trend analysis, regional sources and sinks, and for modeling of long-range transport of CO2. In this study, four approaches are used to filter the atmospheric CO2 observation records from 2009 to 2011 at one World Meteorological Organization/Global Atmosphere Watch (WMO/GAW) regional station (Lin'an, LAN) in China. The methods are based on the atmospheric black carbon concentration (BC), on a statistical approach (REBS), on CH4 as auxiliary tracer (AUX) and on meteorological parameters (MET). All approaches do suitably well to capture the seasonal CO2 cycle at LAN. Differences are observed in the average regional mole fractions with annual values in the REBS method at least 1.7 ± 0.2 ppm higher than the other methods. The BC method may underestimate the regional CO2 mole fractions during winter-spring period and should be treated with caution. The REBS method is a purely statistical method and it may also introduce errors on the regional CO2 mole fractions evaluations, as the filtered trend may be deviated by the "noisy" raw data series. Although there are correlations between CH4 and CO2 mole fractions at LAN, the different source/sink regimes may introduce bias on the regional CO2 estimation in the AUX method, typically in summer. Overall, the MET method seems to be the most favorable because it mainly focuses on the influence of potential local sources and sinks and considers diurnal variations, local topography, and meteorological conditions. Using the MET method, the annual growth rate of regional CO2 at LAN is determined to be 3.1 ± 0.01 ppm yr-1 (standard error) from 2009 to 2013.

  14. Uncertainty and bias of surface ozone measurements at selected Global Atmosphere Watch sites

    NASA Astrophysics Data System (ADS)

    Klausen, JöRg; Zellweger, Christoph; Buchmann, Brigitte; Hofer, Peter

    2003-10-01

    The Global Atmosphere Watch (GAW) program currently coordinates 22 ground-based atmospheric background monitoring stations of global scope. The GAW World Calibration Centre for Surface Ozone, Carbon Monoxide and Methane (WCC-EMPA) is responsible for tracing surface ozone measurements at these stations to the designated reference within the GAW program, the Standard Reference Photometer SRP 2 maintained at the National Institute of Standards and Technology (NIST). The recommended method for surface ozone measurements is based on UV absorption at 254 nm (Hg line). Repeated and regular intercomparisons of station instruments are necessary to achieve and maintain high and known data quality. In this paper, the traceability chain is explained, and standard uncertainties for each element are evaluated. Data of 26 intercomparisons performed at 14 stations between 1996 and 2002 are analyzed. On 23 occasions, the instruments passed the audit with "good" agreement, in one case with "sufficient" agreement. On 2 occasions, both first audits at the site, the audited instrument did not comply with the minimal data quality requirements. The best instruments in use exhibit a median absolute bias of approximately 0.32 ppbv and a standard uncertainty of approximately 0.8 ppbv (0-100 ppbv). The quantitative improvement of data quality as a result of repeated audits can be demonstrated with several stations.

  15. Wrist-watch dosimeter

    DOEpatents

    Wolf, M.A.; Waechter, D.A.; Umbarger, C.J.

    1982-04-16

    The disclosure is directed to a wristwatch dosimeter utilizing a CdTe detector, a microprocessor and an audio and/or visual alarm. The dosimeter is entirely housable within a conventional digital watch case having an additional aperture enabling the detector to receive radiation.

  16. The Monarch Watch.

    ERIC Educational Resources Information Center

    Brown, Ken

    1994-01-01

    Science education can be an exciting process of observation and discovery. This article describes the use of the Monarch Watch project by environmental educators to study migratory behavior and scientific research through the tagging of Monarch butterflies. Discusses reasons the national project has been successful. (LZ)

  17. Logistic transmission models of insulin dependent diabetes from GAW5 data

    SciTech Connect

    Neas, B.R.; Harley, J.B.

    1994-09-01

    A nonparametric and general method of linkage analysis has been developed. The repeated measure strategy of Speilman has been adapted to the conditional logistic function to establish linkage by stepwise modeling of transmission from parent to progeny. No foreknowledges of genetic association, linkage nor mode of inheritance is required. The effects at multiple loci are easily modelled. Such logistic transmission models have been developed from GAW5 data. Serology at HLA-DR is more closely linked to the phenotype than are the other GAW5 HLA loci with coefficients at DR2 of -1.4 (S.E. of 0.4), DR3 of 1.1 (S.E. of 0.2), and DR4 of 1.2 (S.E. of 0.2). Relative to the random transmission of alleles, the model achieves a {chi}{sub 3}{sup 2} of 114 (p<10{sup -24}). From the GAW5 subset with insulin gene data, models incorporating either the insulin gene 1 or the 3 alleles are similar. Overall models from this GAW5 subset are also consistent with genetic heterogeneity at HLA and the insulin gene (e.g., {chi}{sub 1}{sup 2} for improvement > 4.6, overall model {chi}{sub 4}{sup 2} = 71, p=10{sup -18}). Properties of the logistic transmission model suggest this approach will be useful when linkage is sought over small recombination distances, when resistance and susceptibility alleles coexist at a locus, and when a complex mode of inheritance is suspected.

  18. Children under the age of two are more likely to watch inappropriate background media than older children

    PubMed Central

    Tomopoulos, Suzy; Brockmeyer Cates, Carolyn; Dreyer, Benard P; Fierman, Arthur H; Berkule, Samantha B; Mendelsohn, Alan L

    2014-01-01

    Aim To establish whether young children watched foreground electronic media or background media that was not aimed at them or was inappropriate for their age. Methods We performed a longitudinal analysis of mother-infant dyads participating in a larger parenting study. The primary dependent variable was maternal reports of watching habits from media diaries at six, 14, 24 and 36 months. Independent variables were child age, programme content and whether the programme was turned on specifically for the child. Results We analysed 3,570 programme exposures in 527 children, mostly from television. Children were significantly more likely to actually watch programmes if they were older, if the content was coded as “educational-young child” or if the parent tuned on the programme specifically so the child could watch it. Children under the age of two were more likely than older children to watch background media that featured age-inappropriate content or had not been turned on for them to watch (30% versus 16% of programmes; AOR = 2.19, [95%CI 1.82-2.65]). Conclusions Young children under the age of two frequently watch background media that has age-inappropriate content or has not been turned on for them to watch. PMID:24812713

  19. The International Halley Watch

    NASA Technical Reports Server (NTRS)

    1980-01-01

    In preparation for the 1985 to 1986 apparition of Halley's Comet, the International Halley Watch (IHW) has initiated a comprehensive program to simulate, encourage, and coordinate scientific observation of the apparition. The observing groups with which the IHW plans to interact are discussed and the ground based observing nets are described in detail. An outline of the history of observations of Halley's Comet and a synopsis of comet properties and physics are included.

  20. Country watch: Malawi.

    PubMed

    Knox, G

    1995-01-01

    The Drought Network for information sharing eventually led to the establishment of the more formal Southern Region AIDS Network (SORAN) where representatives from government and nongovernmental organizations (NGOs) focused on awareness raising, lobbying, and advocacy. As an initial step towards networking on HIV/AIDS issues, a festival was organized in Blantyre on December 4, 1993, by NGOs, private companies, church groups, school children, and volunteers to bring about behavior change. About 2000 people gathered to listen to music, learn about HIV transmission through drama group presentations, watch videos with HIV/STD prevention messages, and learn about proper condom use. The participants officially established SORAN in February 1994 to act as a coordinating body for organizations working in prevention and care for HIV/STD-infected persons and their families. Network activities endeavored: to assist organizations interested in developing HIV/AIDS programs and activities; to encourage the business communities to participate in multisectoral coordination and to help channel funds from them to HIV/AIDS programs; to act as a resource center for information about HIV/AIDS; and to lobby among politicians as well as traditional local and religious leaders. When the first multi-party parliamentary election approached in May 1994, SORAN challenged representatives of 7 political parties and a women's organization to speak out publicly on what they envisioned doing about HIV/AIDS. The Grand Walk was also organized by SORAN members representing the Catholic Episcopal Conference of Malawi, the Protestant Blantyre Synod, a local brewery, and UNICEF. About 500 walkers received support from passersby. 70% were school children 10-18 years old who sang AIDS awareness songs and passed out flyers. Three months later the National AIDS Program's Big Walk for AIDS, following a National AIDS Crisis Conference, signaled the government's public recognition of the need for a multisectoral approach to combatting HIV/AIDS. PMID:12289026

  1. Proposing a tornado watch scale

    NASA Astrophysics Data System (ADS)

    Mason, Jonathan Brock

    This thesis provides an overview of language used in tornado safety recommendations from various sources, along with developing a rubric for scaled tornado safety recommendations, and subsequent development and testing of a tornado watch scale. The rubric is used to evaluate tornado refuge/shelter adequacy responses of Tuscaloosa residents gathered following the April 27, 2011 Tuscaloosa, Alabama EF4 tornado. There was a significant difference in the counts of refuge adequacy for Tuscaloosa residents when holding the locations during the April 27th tornado constant and comparing adequacy ratings for weak (EF0-EF1), strong (EF2-EF3) and violent (EF4-EF5) tornadoes. There was also a significant difference when comparing future tornado refuge plans of those same participants to the adequacy ratings for weak, strong and violent tornadoes. The tornado refuge rubric is then revised into a six-class, hierarchical Tornado Watch Scale (TWS) from Level 0 to Level 5 based on the likelihood of high-impact or low-impact severe weather events containing weak, strong or violent tornadoes. These levels represent maximum expected tornado intensity and include tornado safety recommendations from the tornado refuge rubric. Audio recordings similar to those used in current National Oceanic and Atmospheric Administration (NOAA) weather radio communications were developed to correspond to three levels of the TWS, a current Storm Prediction Center (SPC) tornado watch and a particularly dangerous situation (PDS) tornado watch. These were then used in interviews of Alabama residents to determine how changes to the information contained in the watch statements would affect each participant's tornado safety actions and perception of event danger. Results from interview participants (n=38) indicate a strong preference (97.37%) for the TWS when compared to current tornado watch and PDS tornado watch statements. Results also show the TWS elicits more adequate safety decisions from participants along with a more appropriate perception of the danger being conveyed by each statement.

  2. Exploration Medical Capability - Technology Watch

    NASA Technical Reports Server (NTRS)

    Krihak, Michael; Watkins, Sharmila; Barr, Yael; Barsten, Kristina; Fung, Paul; Baumann, David

    2011-01-01

    The objectives of the Technology Watch process are to identify emerging, high-impact technologies that augment current ExMC development efforts, and to work with academia, industry, and other government agencies to accelerate the development of medical care and research capabilities for the mitigation of potential health issues that could occur during space exploration missions. The establishment of collaborations with these entities is beneficial to technology development, assessment and/or insertion. Such collaborations also further NASA s goal to provide a safe and healthy environment for human exploration. The Tech Watch project addresses requirements and capabilities identified by knowledge and technology gaps that are derived from a discrete set of medical conditions that are most likely to occur on exploration missions. These gaps are addressed through technology readiness level assessments, market surveys, collaborations and distributed innovation opportunities. Ultimately, these gaps need to be closed with respect to exploration missions, and may be achieved through technology development projects. Information management is a key aspect to this process where Tech Watch related meetings, research articles, collaborations and partnerships are tracked by the HRP s Exploration Medical Capabilities (ExMC) Element. In 2011, ExMC will be introducing the Tech Watch external website and evidence wiki that will provide access to ExMC technology and knowledge gaps, technology needs and requirements documents.

  3. Visual Skills: Watch the Ball?

    ERIC Educational Resources Information Center

    Moen, Sue

    1989-01-01

    In tennis as well as in other racket/paddle sports, simply watching the ball does not guarantee success in hitting the ball to the desired location. Teachers and coaches should teach players to integrate available visual, spatial, and kinesthetic information. Several drills for good ball contact are outlined. (IAH)

  4. The Benefits of Watching Television.

    ERIC Educational Resources Information Center

    Levinson, Paul

    The unfounded and sometimes absurd attacks on television have tended to obscure many of the medium's obvious personal, social, and aesthetic benefits. It is easy to watch, and if its content does not always provide viewers with much to think about, television does not ask much of them either: they may eat, sleep, and unwind in front of it,…

  5. GENOME WATCH Metagenomics with guts

    E-print Network

    Borenstein, Elhanan

    microbiota and the immune system have an important role in many diseases both within and outside the gut1 . Two large collaborative efforts aimed at characterizing the human microbiome have concluded individuals and was discussed in a previous Genome Watch2 . The Human Microbiome Project (HMP) focused mainly

  6. SEA TURTLES Guidelines for watching turtles

    E-print Network

    Exeter, University of

    SEA TURTLES Guidelines for watching turtles At night on the beach please follow the following code the journey every 3 or 4 Where to watch sea turtles on Ascension From December until early March the best, turtle watching is best on a full moon. Walk the beach looking for turtle tracks, these will be about 1

  7. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Watches. 15.705 Section 15.705 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Limitations and Qualifying Factors § 15.705 Watches. (a) Title 46 U.S.C. 8104 applies to the establishment of watches aboard certain U.S. vessels. The...

  8. Long-term trends of surface ozone and its influencing factors at the Mt. Waliguan GAW station, China - Part 1: Overall trends and characteristics

    NASA Astrophysics Data System (ADS)

    Xu, W. Y.; Lin, W. L.; Xu, X. B.; Tang, J.; Huang, J. Q.; Wu, H.; Zhang, X. C.

    2015-11-01

    Tropospheric ozone is an important atmospheric oxidant, greenhouse gas and atmospheric pollutant at the same time. The level of tropospheric ozone, particularly in the surface layer, is impacted by emissions of precursors and is subjected to meteorological conditions. Due its importance, the long-term variation trend of baseline ozone is highly needed for environmental and climate change assessment. So far, studies about the long-term trends of ozone at representative sites are mainly available for European and North American sites. Similar studies are lacking for China, a country with rapid economic growth for recent decades, and many other developing countries. To uncover the long-term characteristics and trends of baseline surface ozone, concentration in western China, measurements at a global baseline Global Atmospheric Watch (GAW) station in the north-eastern Tibetan Plateau region (Mt. Waliguan) for the period of 1994 to 2013 were analysed in this study, using a modified Mann-Kendall test and the Hilbert-Huang Transform analysis for the trend and periodicity analysis, respectively. Results reveal higher surface ozone during the night and lower during the day at Waliguan, due to mountain-valley breezes. A seasonal maximum in summer was found, which was probably caused by enhanced stratosphere-to-troposphere exchange events and/or by tropospheric photochemistry. Analysis suggests that there is a season-diurnal cycle in the three-dimensional winds on top of Mt. Waliguan. Season-dependent daytime and nighttime ranges of 6 h were determined based on the season-diurnal cycle in the three-dimensional winds and were used to sort subsets of ozone data for trend analysis. Significant increasing trends in surface ozone were detected for both daytime (1.5-2.7 ppbv 10 a-1) and nighttime (1.3-2.9 ppbv 10 a-1). Autumn and spring revealed the largest increase rates, while summer and winter showed relatively weaker increases. The HHT spectral analysis confirmed the increasing trends in surface ozone concentration and could further identify four different stages with different increasing rates, with the largest increase occurring around May 2000 and October 2010. A 2-4, 7 and 11 year periodicity was found in the surface ozone concentration. The results are highly valuable for related climate and environment change assessments of western China and surrounding areas, and for the validation of chemical-climate models.

  9. ExMC Technology Watch

    NASA Technical Reports Server (NTRS)

    Krihak, M.; Barr, Y.; Watkins, S.; Fung, P.; McGrath, T.; Baumann, D.

    2012-01-01

    The Technology Watch (Tech Watch) project is a NASA endeavor conducted under the Human Research Programs (HRP) Exploration Medical Capability (ExMC) element, and focusing on ExMC technology gaps. The project involves several NASA centers, including the Johnson Space Center (JSC), Glenn Research Center (GRC), Ames Research Center (ARC), and the Langley Research Center (LaRC). The objective of Tech Watch is to identify emerging, high-impact technologies that augment current NASA HRP technology development efforts. Identifying such technologies accelerates the development of medical care and research capabilities for the mitigation of potential health issues encountered during human space exploration missions. The aim of this process is to leverage technologies developed by academia, industry and other government agencies and to identify the effective utilization of NASA resources to maximize the HRP return on investment. The establishment of collaborations with these entities is beneficial to technology development, assessment and/or insertion and further NASAs goal to provide a safe and healthy environment for human exploration. In 2011, the major focus areas for Tech Watch included information dissemination, education outreach and public accessibility to technology gaps and gap reports. The dissemination of information was accomplished through site visits to research laboratories and/or companies, and participation at select conferences where Tech Watch objectives and technology gaps were presented. Presentation of such material provided researchers with insights on NASA ExMC needs for space exploration and an opportunity to discuss potential areas of common interest. The second focus area, education outreach, was accomplished via two mechanisms. First, several senior student projects, each related to an ExMC technology gap, were sponsored by the various NASA centers. These projects presented ExMC related technology problems firsthand to collegiate laboratories. Second, a RASC-AL (Revolutionary Aerospace Systems Concepts Academic Linkage) topic for FY12 was developed for medical systems and astronaut health under the Human-Focused Mars Mission Systems and Technologies theme. Announcement of the competition was made to the public in August 2011. Finally, critical Tech Watch information was prepared for public release in the form of gap reports. Complementing the ExMC technology gaps in the public domain, gap reports were generated, reviewed and revised through a series of technical, medical and subject matter expert reviews before approval for public release. An important vehicle for the public release of such documents was development of the ExMC wiki website, which will continue to be populated with gap reports and relevant documents throughout the upcoming year.

  10. ExMC Technology Watch

    NASA Technical Reports Server (NTRS)

    Krihak, M.; Barr, Y.; Watkins, S.; Fung, P.; McGrath, T.; Baumann, D.

    2012-01-01

    The Technology Watch (Tech Watch) project is a NASA endeavor conducted under the Human Research Program's (HRP) Exploration Medical Capability (ExMC) element, and focusing on ExMC technology gaps. The project involves several NASA centers, including the Johnson Space Center (JSC), Glenn Research Center (GRC), Ames Research Center (ARC), and the Langley Research Center (LaRC). The objective of Tech Watch is to identify emerging, high-impact technologies that augment current NASA HRP technology development efforts. Identifying such technologies accelerates the development of medical care and research capabilities for the mitigation of potential health issues encountered during human space exploration missions. The aim of this process is to leverage technologies developed by academia, industry and other government agencies and to identify the effective utilization of NASA resources to maximize the HRP return on investment. The establishment of collaborations with these entities is beneficial to technology development, assessment and/or insertion and further NASA's goal to provide a safe and healthy environment for human exploration. In 2011, the major focus areas for Tech Watch included information dissemination, education outreach and public accessibility to technology gaps and gap reports. The dissemination of information was accomplished through site visits to research laboratories and/or companies, and participation at select conferences where Tech Watch objectives and technology gaps were presented. Presentation of such material provided researchers with insights on NASA ExMC needs for space exploration and an opportunity to discuss potential areas of common interest. The second focus area, education outreach, was accomplished via two mechanisms. First, several senior student projects, each related to an ExMC technology gap, were sponsored by the various NASA centers. These projects presented ExMC related technology problems firsthand to collegiate laboratories. Second, a RASC-AL (Revolutionary Aerospace Systems Concepts - Academic Linkage) topic for FY12 was developed for medical systems and astronaut health under the Human-Focused Mars Mission Systems and Technologies theme. Announcement of the competition was made to the public in August 2011. Finally, critical Tech Watch information was prepared for public release in the form of gap reports. Complementing the ExMC technology gaps in the public domain, gap reports were generated, reviewed and revised through a series of technical, medical and subject matter expert reviews before approval for public release. An important vehicle for the public release of such documents was development of the ExMC wiki website, which will continue to be populated with gap reports and relevant documents throughout the upcoming year.

  11. ExMC Technology Watch

    NASA Technical Reports Server (NTRS)

    Krihak, M.; Watkins, S.; Fung, Paul P.

    2013-01-01

    The Technology Watch (Tech Watch) project is a NASA project that is operated under the Human Research Programs (HRP) Exploration Medical Capability (ExMC) element, and focuses on ExMC technology gaps. The project coordinates the efforts of several NASA centers, including the Johnson Space Center (JSC), Glenn Research Center (GRC), Ames Research Center (ARC), and the Langley Research Center (LaRC). The objective of Tech Watch is to identify emerging, high-impact technologies that augment current NASA HRP technology development efforts. Identifying such technologies accelerates the development of medical care and research capabilities for the mitigation of potential health issues encountered during human space exploration missions. The aim of this process is to leverage technologies developed by academia, industry and other government agencies and to identify the effective utilization of NASA resources to maximize the HRP return on investment. The establishment of collaborations with these entities is beneficial to technology development, assessment and/or insertion and further NASAs goal to provide a safe and healthy environment for human exploration. In 2012, the Tech Watch project expanded the scope of activities to cultivate student projects targeted at specific ExMC gaps, generate gap reports for a majority of the ExMC gaps and maturate a gap report review process to optimize the technical and managerial aspects of ExMC gap status. Through numerous site visits and discussions with academia faculty, several student projects were initiated and/or completed this past year. A key element to these student projects was the ability of the project to align with a specific ExMC technology or knowledge gap. These projects were mentored and reviewed by Tech Watch leads at the various NASA centers. Another result of the past years efforts was the population of the ExMC wiki website that now contains more the three quarters of the ExMC gap reports. The remaining gap reports will be completed in FY13. Finally, the gap report review process for all ExMC gaps was initiated. This review process was instrumental in ensuring that each gap report was thoroughly reviewed for accuracy and relevant content prior to its public release. In the upcoming year, the gap report review process will be refined such that in addition to the gap report update, programmatic information related to gap closure will also be emphasized.

  12. ExMC Technology Watch

    NASA Technical Reports Server (NTRS)

    Krihak, M.; Watkins, S.; Shaw, T.

    2014-01-01

    The Technology Watch (Tech Watch) project is directed by the NASA Human Research Program's (HRP) Exploration Medical Capability (ExMC) element, and primarily focuses on ExMC technology gaps. The project coordinates the efforts of multiple NASA centers, including the Johnson Space Center (JSC), Glenn Research Center (GRC), Ames Research Center (ARC), and the Langley Research Center (LaRC). The objective of Tech Watch is to identify emerging, high-impact technologies that augment current NASA HRP technology development efforts. Identifying such technologies accelerates the development of medical care and research capabilities for the mitigation of potential health issues encountered during human space exploration missions. The aim of this process is to leverage technologies developed by academia, industry and other government agencies and to identify the effective utilization of NASA resources to maximize the HRP return on investment. The establishment of collaborations with these entities is beneficial to technology development, assessment and/or insertion, and advance NASA's goal to provide a safe and healthy environment for human exploration. In fiscal year 2013, the Tech Watch project maintained student project activity aimed at specific ExMC gaps, completed the gap report review cycle for all gaps through a maturated gap report review process, and revised the ExMC Tech Watch Sharepoint site for enhanced data content and organization. Through site visits, internships and promotions via aerospace journals, several student projects were initiated and completed this past year. Upon project completion, the students presented their results via telecom or WebEx to the ExMC Element as a whole. The upcoming year will continue to forge strategic alliances and student projects in the interest of technology and knowledge gap closure. Through the population of Sharepoint with technologies assessed by the gap owners, the database expansion will develop a more comprehensive technology set for each gap. By placing such data in Sharepoint, the gap report updates in fiscal year 2014 are anticipated to be streamlined since the evaluated technologies will be readily available to the gap owners in a sortable archive, and may be simply exported into the final gap report presentation

  13. ExMC Technology Watch

    NASA Technical Reports Server (NTRS)

    Krihak, M.; Watkins, S.; Shaw, T.

    2014-01-01

    The Technology Watch (Tech Watch) project is directed by the NASA Human Research Programs (HRP) Exploration Medical Capability (ExMC) element, and primarily focuses on ExMC technology gaps. The project coordinates the efforts of multiple NASA centers, including the Johnson Space Center (JSC), Glenn Research Center (GRC), Ames Research Center (ARC), and the Langley Research Center (LaRC). The objective of Tech Watch is to identify emerging, high-impact technologies that augment current NASA HRP technology development efforts. Identifying such technologies accelerates the development of medical care and research capabilities for the mitigation of potential health issues encountered during human space exploration missions. The aim of this process is to leverage technologies developed by academia, industry and other government agencies and to identify the effective utilization of NASA resources to maximize the HRP return on investment. The establishment of collaborations with these entities is beneficial to technology development, assessment and/or insertion, and advance NASAs goal to provide a safe and healthy environment for human exploration. In fiscal year 2013, the Tech Watch project maintained student project activity aimed at specific ExMC gaps, completed the gap report review cycle for all gaps through a maturated gap report review process, and revised the ExMC Tech Watch Sharepoint site for enhanced data content and organization. Through site visits, internships and promotions via aerospace journals, several student projects were initiated and completed this past year. Upon project completion, the students presented their results via telecom or WebEx to the ExMC Element as a whole. The upcoming year will continue to forge strategic alliances and student projects in the interest of technology and knowledge gap closure. Through the population of Sharepoint with technologies assessed by the gap owners, the database expansion will develop a more comprehensive technology set for each gap. By placing such data in Sharepoint, the gap report updates in fiscal year 2014 are anticipated to be streamlined since the evaluated technologies will be readily available to the gap owners in a sortable archive, and may be simply exported into the final gap report presentation.

  14. Antibodies to watch in 2015

    PubMed Central

    Reichert, Janice M

    2015-01-01

    The commercial pipeline of recombinant antibody therapeutics is robust and dynamic. As of early December 2014, a total of 6 such products (vedolizumab, siltuximab, ramucirumab, pembrolizumab, nivolumab, blinatumomab) were granted first marketing approvals in 2014. As discussed in this perspective on antibodies in late-stage development, the outlook for additional approvals, potentially still in 2014 and certainly in 2015, is excellent as marketing applications for 6 antibody therapeutics (secukinumab, evolocumab, mepolizumab, dinutuximab, nivolumab, necitumumab) are undergoing a first regulatory review in the EU or US. Of the 39 novel mAbs currently in Phase 3 studies, a marketing application for one (alirocumab) may be submitted in late 2014, and marketing application submissions for at least 4 (reslizumab, ixekizumab, ocrelizumab, obiltoxaximab) are expected in 2015. Other ‘antibodies to watch’ are those in Phase 3 studies with estimated primary completion dates in late 2014 or 2015, which includes 13 for non-cancer indications (brodalumab, bimagrumab, bococizumab, MABp1, gevokizumab, dupilumab, sirukumab, sarilumab, tildrakizumab, guselkumab, epratuzumab, combination of actoxumab + bezlotoxumab, romosozumab) and 2 (racotumomab and clivatuzumab tetraxetan) undergoing evaluation as treatments for cancer. In addition to the novel antibody therapeutics mentioned, biosimilar infliximab and biosimilar trastuzumab are ‘antibodies to watch’ in 2015 because of their potential for entry into the US market and regulatory review, respectively. PMID:25484055

  15. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 false Watch requirements for ship stations. 80.1123 Section 80.1123 ...Communications § 80.1123 Watch requirements for ship stations. (a) While at sea, all ships must maintain a continuous watch: (1)...

  16. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 false Watch requirements for ship stations. 80.1123 Section 80.1123 ...Communications § 80.1123 Watch requirements for ship stations. (a) While at sea, all ships must maintain a continuous watch: (1)...

  17. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 false Watch requirements for ship stations. 80.1123 Section 80.1123 ...Communications § 80.1123 Watch requirements for ship stations. (a) While at sea, all ships must maintain a continuous watch: (1)...

  18. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...2010-10-01 false Watch requirements for ship stations. 80.1123 Section 80.1123 ...Communications § 80.1123 Watch requirements for ship stations. (a) While at sea, all ships must maintain a continuous watch: (1)...

  19. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...2011-10-01 false Watch requirements for ship stations. 80.1123 Section 80.1123 ...Communications § 80.1123 Watch requirements for ship stations. (a) While at sea, all ships must maintain a continuous watch: (1)...

  20. 29 CFR 1915.504 - Fire watches.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 CFR Part 1915, Subpart B, requires that a fire watch be posted. (c) Assigning employees to fire... personal protective equipment (PPE) that must be made available and worn as required by 29 CFR Part 1915... 29 Labor 7 2013-07-01 2013-07-01 false Fire watches. 1915.504 Section 1915.504 Labor...

  1. 29 CFR 1915.504 - Fire watches.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 CFR Part 1915, Subpart B, requires that a fire watch be posted. (c) Assigning employees to fire... personal protective equipment (PPE) that must be made available and worn as required by 29 CFR Part 1915... 29 Labor 7 2012-07-01 2012-07-01 false Fire watches. 1915.504 Section 1915.504 Labor...

  2. 29 CFR 1915.504 - Fire watches.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 CFR Part 1915, Subpart B, requires that a fire watch be posted. (c) Assigning employees to fire... personal protective equipment (PPE) that must be made available and worn as required by 29 CFR Part 1915... 29 Labor 7 2014-07-01 2014-07-01 false Fire watches. 1915.504 Section 1915.504 Labor...

  3. 29 CFR 1915.504 - Fire watches.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 CFR Part 1915, Subpart B, requires that a fire watch be posted. (c) Assigning employees to fire... personal protective equipment (PPE) that must be made available and worn as required by 29 CFR Part 1915... 29 Labor 7 2011-07-01 2011-07-01 false Fire watches. 1915.504 Section 1915.504 Labor...

  4. 29 CFR 1915.504 - Fire watches.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 CFR Part 1915, Subpart B, requires that a fire watch be posted. (c) Assigning employees to fire... personal protective equipment (PPE) that must be made available and worn as required by 29 CFR Part 1915... 29 Labor 7 2010-07-01 2010-07-01 false Fire watches. 1915.504 Section 1915.504 Labor...

  5. 75 FR 49510 - Credit Watch Termination Initiative

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ...'s mortgagee approval regulations at 24 CFR 202.3. On May 17, 1999 HUD published a notice (64 FR... URBAN DEVELOPMENT Credit Watch Termination Initiative AGENCY: Office of the Assistant Secretary for... (FHA) against HUD-approved mortgagees through the FHA Credit Watch Termination Initiative. This...

  6. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Watches. 15.705 Section 15.705 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Limitations and Qualifying Factors § 15.705 Watches. (a) Title 46 U.S.C. 8104 is the law applicable to the establishment...

  7. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Watches. 15.705 Section 15.705 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Limitations and Qualifying Factors § 15.705 Watches. (a) Title 46 U.S.C. 8104 is the law applicable to the establishment...

  8. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Watches. 15.705 Section 15.705 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Limitations and Qualifying Factors § 15.705 Watches. (a) Title 46 U.S.C. 8104 is the law applicable to the establishment...

  9. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Watches. 15.705 Section 15.705 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Limitations and Qualifying Factors § 15.705 Watches. (a) Title 46 U.S.C. 8104 is the law applicable to the establishment...

  10. FIRST teams watch the competition

    NASA Technical Reports Server (NTRS)

    2000-01-01

    FIRST teams watch robots in action during the FIRST competition. Students from all over the country are at the KSC Visitor Complex for the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition March 9-11 in the Rocket Garden. Teams of high school students are testing the limits of their imagination using robots they have designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing, 16 are Florida teams co-sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville.

  11. Turkey Watch: EU Member States' Perceptions on Turkey's Accession to ISBN: 978-605-89751-2-5

    E-print Network

    Hasýrcý, Vasýf

    #12;#12;#12;#12;#12;1 Turkey Watch: EU Member States' Perceptions on Turkey's Accession to the EU Technical University, Ankara, Turkey. SInAN logosu ve Strengthening and Integrating Academic Networks University under the Programme `Promotion of Civil Society Dialogue between the EU and Turkey: Universities

  12. Watching the Moon from Tenerife

    ERIC Educational Resources Information Center

    Baruch, John; Machell, James; Norris, Kath

    2005-01-01

    "Where does the Sun go at night?" or "Why don't the Australians fall off?" are typical of the innocent questions that children ask. A new "Earth and Beyond" primary science learning programme from the University of Bradford is piloting some exciting ways to engage children with these questions and providing opportunities for them to find answers…

  13. Radon Emissions from Radium-Dial Watches.

    NASA Astrophysics Data System (ADS)

    Gillmore, G.; Crockett, R.

    2012-04-01

    Preliminary research during the latter half of 2011 has indicated that significant and potentially hazardous radon concentrations can arise from radium-dial watches stored in the built environment. Radium (226Ra) decays via alpha-particle emission to radon (222Rn); in addition, mesothorium (228Ra) and radiothorium (228Th) were also used in such watches and decay to thoron (220Rn). In the main experiments conducted to date, a set of radium-dial watches representative of a small private collection, was placed in a controlled access room, of volume 67 m3, that is continuously ventilated to the external environment. Prior to placing the watches in the room, the radon level at the maximum ventilation rate was ca. 10 Bq/m3. This rose to ca. 190-230 Bq/m3 following the placing of the watches in the room, again under conditions of maximum ventilation. When the ventilation rate decreased to a 'standby' setting, the radon concentration increased rapidly to ca. 2-3 kBq/m3, then decreased rapidly to the lower concentration when the ventilation rate returned to maximum. Extrapolation of results of monitoring a single watch under zero-ventilation conditions indicates that the zero-ventilation equilibrium concentration in the room arising from the set of watches exceeds 5 kBq/m3 and Monte-Carlo simulation indicates this could exceed 10 kBq/m3, both of which are greatly in excess of the UK Action Levels. Observation of such levels is largely unreported in the literature and our preliminary conclusion is that whilst collectors might be aware of the radiation hazard that arises directly from the radioactive material content of such watches, they are probably not aware of the large radon (and thoron) hazard that can arise, particularly if the watches are kept in a poorly ventilated room in a private house.

  14. Development of a new concept diver's watch

    NASA Astrophysics Data System (ADS)

    Tsunoda, Takeo; Aizawa, Hitomi

    The 'Scuba Master' diver's watch represents a new concept. It was developed and announced in 1990. This watch automatically displays information necessary for safe scuba diving and records diving data. The watch was well accepted by divers all over the world. Safe diving techniques were investigated. This led to the need for developing a highly accurate, highly reliable depth measurement system. The functions and features of 'Scuba Masters' are described. The way to make the depth measurement system highly accurate and highly reliable is explained.

  15. Flood Watch A new service for the Queensland community

    E-print Network

    Greenslade, Diana

    Flood Watch A new service for the Queensland community What is a FloodWatch? Flood Watch there is an increased risk of riverine flooding. It joins the best of our rainfall and flood forecasting capabilities into a single product. Flood Watches will be available from 15 October 2014, allowing Queenslanders to make

  16. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...certificate of inspection take into consideration routine maintenance requirements and ability of the crew to perform all operational evolutions, including emergencies, as well as those functions which may be assigned to persons in watches. (b) Subject...

  17. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...manning document take into consideration routine maintenance requirements and ability of the crew to perform all operational evolutions, including emergencies, as well as those functions which may be assigned to persons in watches. (b) Subject to...

  18. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...certificate of inspection take into consideration routine maintenance requirements and ability of the crew to perform all operational evolutions, including emergencies, as well as those functions which may be assigned to persons in watches. (b) Subject...

  19. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...certificate of inspection take into consideration routine maintenance requirements and ability of the crew to perform all operational evolutions, including emergencies, as well as those functions which may be assigned to persons in watches. (b) Subject...

  20. 46 CFR 15.705 - Watches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...certificate of inspection take into consideration routine maintenance requirements and ability of the crew to perform all operational evolutions, including emergencies, as well as those functions which may be assigned to persons in watches. (b) Subject...

  1. National Weather Service: Watch, Warning, Advisory Display

    MedlinePLUS

    ... Fire Wx Outlooks RSS Feeds E-Mail Alerts Weather Information Storm Reports Storm Reports Dev. NWS Hazards ... Watch/Warning Map National RADAR Product Archive NOAA Weather Radio Research Non-op. Products Forecast Tools Svr. ...

  2. PROGRAMME SPECIFICATION Programme title: Statistics

    E-print Network

    Guillas, Serge

    PROGRAMME SPECIFICATION Programme title: Statistics Final award (BSc, MA etc): (where stopping off in statistical computing and communication are assessed by coursework only. The summer project is assessed Sciences (MAPS) Parent Department: (the department responsible for the administration of the programme

  3. Department of Energy Support for Operations of the WMO/GAW Quality Control/Science Activity Center for the Americas

    SciTech Connect

    Hicks, B. B.

    2003-11-13

    As a formal activity of the World Meteorological Organization's Global Atmosphere Watch, to provide, through agency collaboration, a center of excellence in the United States that would impose quality assurance techniques on data collected by national air and precipitation quality networks operating in the Americas (north, south, and central).

  4. Radium dial watches, a potentially hazardous legacy?

    PubMed

    Gillmore, Gavin K; Crockett, Robin; Denman, Tony; Flowers, Alan; Harris, Richard

    2012-09-15

    This study re-examines the risk to health from radium ((226)Ra) dial watches. Ambient dose equivalent rates have been measured for fifteen pocket watches giving results of up to 30 ?Sv h(-1) at a distance of 2 cm taken with a series 1000 mini-rad from the front face (arithmetic mean ambient dose equivalent for pocket watches being 13.2 ?Sv h(-1)). A pocket compass gave rise to a similar ambient dose equivalent rate, of 20 ?Sv h(-1), to the pocket watches, with its cover open. Eighteen wristwatches have also been assessed, but their dose rates are generally much lower (the arithmetic mean being 3.0 ?Sv h(-1)), although the highest ambient dose equivalent rate noted was 20 ?Sv h(-1). A phantom experiment using a TLD suggested an effective dose equivalent of 2.2 mSv/y from a 1 ?Ci (37 kBq) radium dial worn for 16 h/day throughout the year (dose rate 0.375 ?Sv h(-1)). For this condition we estimated maximum skin dose for our pocket watches as 16 mSv per year, with effective doses of 5.1 mSv and 1.169 mSv when worn in vest and trouser pockets respectively. This assumes exposure from the back of the watch which is generally around 60-67% of that from the front. The maximum skin dose from a wristwatch was 14 mSv, with 4.2 mSv effective dose in vest pocket. Radium ((226)Ra) decays to the radioactive gas radon ((222)Rn), and atmospheric radon concentration measurements taken around a pocket watch in a small sealed glass sphere recorded 18,728 B qm(-3). All watches were placed in a room with a RAD7 real-time radon detector. Radon concentration average was 259±9 Bq m(-3) over 16 h, compared to background average over 24h of 1.02 Bq m(-3). Over 6 weeks highs of the order of 2000 Bq m(-3) were routinely recorded when the heating/ventilation system in the room was operating at reduced rates, peaking at over 3000 Bq m(-3) on several occasions. Estimates of the activity of (226)Ra in the watches ranged from 0.063 to 1.063 ?Ci (2.31 to 39.31 kBq) for pocket watches and from 0.013 to 0.875 ?Ci (0.46 to 32.38 kBq) for wrist watches. The risk from old watches containing radium appears to have been largely forgotten today. This paper indicates a health risk, particular to collectors, but with knowledge and appropriate precautions the potential risks can be reduced. PMID:22580295

  5. Should I Let My Child Watch Television?

    ERIC Educational Resources Information Center

    Bharadwaj, Balaji

    2013-01-01

    While the prevalence of autism has been increasing globally, there is a search for the causative factors behind the rise. The point of view presented here examines the possibility of children brought up in social deprivation and watching television being at higher risk for developing autistic symptoms. The association is evident in the clinical…

  6. 10 Trends to Watch in Campus Technology

    ERIC Educational Resources Information Center

    Martin, James; Samels, James E.

    2007-01-01

    College and university presidents are increasingly called upon to make informed choices about technology. The rapidly shifting landscape makes it tough to keep up with change and innovation, let alone stay ahead of the curve. In this article, the authors discuss 10 trends to watch in campus technology. These trends are the following: (1) increased…

  7. The Quartz Analog Watch: A Wonder Machine.

    ERIC Educational Resources Information Center

    Crane, H. Richard, Ed.

    1993-01-01

    Summarizes how a quartz watch works. Discusses the quartz crystal, its form, and how its frequency is set to a standard; the integrated circuit chip that drives the crystal in vibration, scales its frequency down, and forms pulses that turn the motor; and the motor that drives the gear train that turns the hands. (ZWH)

  8. Perceptions of Learning among Swiss Watch Managers

    ERIC Educational Resources Information Center

    Tajeddini, Kayhan

    2009-01-01

    Purpose: This paper aims to explore managers' perceptions of learning within a sample of Swiss watch firms. Design/methodology/approach: A purposeful (judgmental) stratified sampling method was employed, where in-depth interviews with 13 marketing managers and owners were carried out over a three-month period. Meaning units (MUs) were abstracted,…

  9. Whale Watching in the Gulf of Maine.

    ERIC Educational Resources Information Center

    Carkin, Clayton A.

    1985-01-01

    Describes a variety of teaching strategies to prepare a class for a whale watching field trip. Guidelines for recording a sighting, pictures and statistics for commonly and/or occasionally seen whales, and hints for avoiding sea sickness are included. (DH)

  10. Whale Watching: 1. BE CAUTIOUS and COURTEOUS

    E-print Network

    Acevedo, Alejandro

    DOWN: reduce speed to less than 7 knots when within 400 metres/yards of the nearest whale. Avoid abrupt of many vessels and give consideration to other viewers. 9. DO NOT swim with or feed whales. Porpoises and dolphins: 1. OBSERVE all guidelines for watching whales. 2. DO NOT drive through groups of porpoises

  11. 47 CFR 80.882 - 2182 kHz watch.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false 2182 kHz watch. 80.882 Section 80.882 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... kHz watch. Ships subject to this subpart must maintain a watch on the frequency 2182 kHz pursuant...

  12. 47 CFR 80.882 - 2182 kHz watch.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false 2182 kHz watch. 80.882 Section 80.882 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... kHz watch. Ships subject to this subpart must maintain a watch on the frequency 2182 kHz pursuant...

  13. 47 CFR 80.882 - 2182 kHz watch.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false 2182 kHz watch. 80.882 Section 80.882 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... kHz watch. Ships subject to this subpart must maintain a watch on the frequency 2182 kHz pursuant...

  14. 47 CFR 80.882 - 2182 kHz watch.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false 2182 kHz watch. 80.882 Section 80.882 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... kHz watch. Ships subject to this subpart must maintain a watch on the frequency 2182 kHz pursuant...

  15. 28 CFR 552.42 - Suicide watch conditions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Suicide watch conditions. 552.42 Section... CUSTODY Suicide Prevention Program § 552.42 Suicide watch conditions. (a) Housing. Each institution must have one or more rooms designated specifically for housing an inmate on suicide watch. The...

  16. 28 CFR 552.42 - Suicide watch conditions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Suicide watch conditions. 552.42 Section... CUSTODY Suicide Prevention Program § 552.42 Suicide watch conditions. (a) Housing. Each institution must have one or more rooms designated specifically for housing an inmate on suicide watch. The...

  17. 28 CFR 552.42 - Suicide watch conditions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Suicide watch conditions. 552.42 Section... CUSTODY Suicide Prevention Program § 552.42 Suicide watch conditions. (a) Housing. Each institution must have one or more rooms designated specifically for housing an inmate on suicide watch. The...

  18. 28 CFR 552.42 - Suicide watch conditions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Suicide watch conditions. 552.42 Section... CUSTODY Suicide Prevention Program § 552.42 Suicide watch conditions. (a) Housing. Each institution must have one or more rooms designated specifically for housing an inmate on suicide watch. The...

  19. 28 CFR 552.42 - Suicide watch conditions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Suicide watch conditions. 552.42 Section... CUSTODY Suicide Prevention Program § 552.42 Suicide watch conditions. (a) Housing. Each institution must have one or more rooms designated specifically for housing an inmate on suicide watch. The...

  20. Impact on Psychiatric Interns of Watching Live Electroconvulsive Treatment

    ERIC Educational Resources Information Center

    Gazdag, Gabor; Sebestyen, Gabor; Ungvari, Gabor S.; Tolna, Judit

    2009-01-01

    Objective: Watching a live electroconvulsive treatment (ECT) has both positive and negative effects on spectators. The authors aim to survey the attitude change towards ECT in interns after watching a live ECT session. Methods: A 23-item questionnaire was administered to 66 interns before and after watching ECT. Results: In five statements, the…

  1. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch requirements for ship stations. 80.1123... Procedures for Distress and Safety Communications § 80.1123 Watch requirements for ship stations. (a) While at sea, all ships must maintain a continuous watch: (1) On VHF DSC channel 70, if the ship is...

  2. Additional flow field studies of the GA(W)-1 airfoil with 30-percent chord Fowler flap including slot-gap variations and cove shape modifications

    NASA Technical Reports Server (NTRS)

    Wentz, W. H., Jr.; Ostowari, C.

    1983-01-01

    Experimental measurements were made to determine the effects of slot gap opening and flap cove shape on flap and airfoil flow fields. Test model was the GA(W)-1 airfoil with 0.30c Fowler flap deflected 35 degrees. Tests were conducted with optimum, wide and narrow gaps, and with three cove shapes. Three test angles were selected, corresponding to pre-stall and post-stall conditions. Reynolds number was 2,200,000 and Mach number was 0.13. Force, surface pressure, total pressure, and split-film turbulence measurements were made. Results were compared with theory for those parameters for which theoretical values were available.

  3. The Verification of MACC-II Global Reactive Gas Forecasts with Global Atmosphere Watch Surface Observations and Ozonesonde Measurements from the NDACC, WOUDC, NILU and SHADOZ Databases

    NASA Astrophysics Data System (ADS)

    Wagner, A.

    2012-04-01

    The MACC-II (Monitoring Atmospheric Composition and Climate- phase II) project, funded under the 7th framework program of the European Union, provides a comprehensive monitoring and operational forecasting system for atmospheric constituents relevant to climate and air quality issues and surface solar radiation. The MACC-II forecast system is based on the global weather forecasting system operated by the European Centre for Medium-Range Weather Forecasts (ECMWF) coupled with the chemistry transport models MOZART (Model for OZone and Related chemical Tracers) and TM5. On a near real time (NRT) basis observational data and forecasts, as well as reanalyses are made available for greenhouse and reactive gases, UV radiation and aerosol optical density. The sub group "VAL" is focusing on the evaluation of reactive gases, thus, stratospheric and tropospheric ozone as well as its precursors and aerosols. The GAW (Global Atmosphere Watch) network provides the ground-based observational data for the evaluation of model simulation forecast and reanalysis of the reactive gases CO and O3 at surface levels on a global scale. Contributing stations in this validation process provide their data in rapid delivery mode (within 1 day to 1 month), thus enabling a fast evaluation process. Currently, there are 12 stations providing data in Near-Real-Time. The validation process is performed online and daily updates of the results are displayed on the MACC website (http://www.gmes-atmosphere.eu/d/services/gac/verif/grg/gaw/). For the validation of stratospheric and free tropospheric ozone forecasts, balloon sonde measurements from the data bases NDACC (Network for the Detection of Atmospheric Composition Change), WOUDC (World Ozone and Ultraviolet Radiation Data Centre), NILU (Norwegian Institute for Air Research) and SHADOZ (Southern Hemisphere Additional OZon Sondes) are used. Here, we will give an overview on the status and the results of this Near-Real-Time (NRT) validation of the coupled forecast system for surface O3 and CO, based on GAW observational data, as well as for stratospheric ozone based on NDACC, WOUDC, NILU and SHADOZ sonde data. This work is supported by the EU-funded project MACC-II.

  4. Programmable Oscillator

    NASA Technical Reports Server (NTRS)

    Quirk, Kevin J.; Patawaran, Ferze D.; Nguyen, Danh H.; Lee, Clement G.; Nguyen, Huy

    2011-01-01

    A programmable oscillator is a frequency synthesizer with an output phase that tracks an arbitrary function. An offset, phase-locked loop circuit is used in combination with an error control feedback loop to precisely control the output phase of the oscillator. To down-convert the received signal, several stages of mixing may be employed with the compensation for the time-base distortion of the carrier occurring at any one of those stages. In the Goldstone Solar System Radar (GSSR), the compensation occurs in the mixing from an intermediate frequency (IF), whose value is dependent on the station and band, to a common IF used in the final stage of down-conversion to baseband. The programmable oscillator (PO) is used in the final stage of down-conversion to generate the IF, along with a time-varying phase component that matches the time-base distortion of the carrier, thus removing it from the final down-converted signal.

  5. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...

  6. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...

  7. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...

  8. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...

  9. 47 CFR 80.309 - Watch required by the Bridge-to-Bridge Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Watch required by the Bridge-to-Bridge Act. 80... Safety Watches § 80.309 Watch required by the Bridge-to-Bridge Act. In addition to the watch requirement contained in § 80.148, all vessels subject to the Bridge-to-Bridge Act must keep a watch on the...

  10. Boreal Forest Watch: A BOREAS Outreach Program

    NASA Technical Reports Server (NTRS)

    Rock, Barrett N.

    1999-01-01

    The Boreal Forest Watch program was initiated in the fall of 1994 to act as an educational outreach program for the BOREAS project in both the BOREAS Southern Study Area (SSA) and Northern Study Area (NSA). Boreal Forest Watch (13FW) was designed to introduce area high school teachers and their students to the types of research activities occurring as part of the BOREAS study of Canadian boreal forests. Several teacher training workshops were offered to teachers from central and northern Saskatchewan and northern Manitoba between May, 1995 and February, 1999; teachers were introduced to techniques for involving their students in on-going environmental monitoring studies within local forested stands. Boreal Forest Watch is an educational outreach program which brings high school students and research scientists together to study the forest and foster a sustainable relationship between people and the planetary life-support system we depend upon. Personnel from the University of New Hampshire (UNH), Complex Systems Research Center (CSRC), with the cooperation from the Prince Albert National Park (PANP), instituted this program to help teachers within the BOREAS Study Areas offer real science research experience to their students. The program has the potential to complement large research projects, such as BOREAS, by providing useful student- collected data to scientists. Yet, the primary goal of BFW is to allow teachers and students to experience a hands-on, inquiry-based approach to leaming science - emulating the process followed by research scientists. In addition to introducing these teachers to on-going BOREAS research, the other goals of the BFW program were to: 1) to introduce authentic science topics and methods to students and teachers through hands-on, field-based activities; and, 2) to build a database of student-collected environmental monitoring data for future global change studies in the boreal region.

  11. The IHW island network. [International Halley Watch

    NASA Technical Reports Server (NTRS)

    Niedner, Malcolm B., Jr.; Liller, William

    1987-01-01

    Early astronomical photography of comets at perihelion encouraged the establishment of an International Halley Watch (IHW) Team for regularly photographing the Comet. The February 1986 period was particularly troublesome due to the limitations of cometary visibility in the Southern Hemisphere. Schmidt cameras were placed on Tahiti, Easter Island, Faraday Station on the Antarctic Peninsula, Reunion Island and in South Africa. Blue- and red-filter B/W images were obtained every night and color prints were occasionally shot. Each night's images were examined before the next night's photography. Several interesting anecdotes are recounted from shipping, manning and operation of the telescopes.

  12. A watch on the watch Whether we use our fingertips to

    E-print Network

    van Vliet, Lucas J.

    a glucose- and dehydration-monitoring watch. The glucose sensor is the first wearable device that can heart rate. "Biometric monitoring can prevent many serious health issues by providing an early warn- ing of the day, we've all monitored our bodies from time to time - and it can be sketchy at best. For many

  13. The GAW-PFR aerosol optical depth network: The 2008-2013 time series at Cape Point Station, South Africa

    NASA Astrophysics Data System (ADS)

    Nyeki, S.; Wehrli, C.; Gröbner, J.; Kouremeti, N.; Wacker, S.; Labuschagne, C.; Mbatha, N.; Brunke, E.-G.

    2015-05-01

    A ground-based aerosol optical depth (AOD) climatology is presented for Cape Point (CPT) station, South Africa, for the 2008-2013 period. CPT is part of the Global Atmosphere Watch-Precision Filter Radiometer network which conducts long-term AOD measurements at remote background sites. AOD (? = 500 nm) and Ångström exponent (368 to 862 nm; ?368-862) averages for the entire period were 0.059 and 0.68, displaying only a weak seasonality. Based on an established method for air mass classification using the in situ wind direction and 222Rn concentration, the following four air mass types were used to further investigate AOD: background marine, marine, mixed, and continental. AOD was similar for all types, but ?368-862 was distinctly lower (0.43) for background marine and higher (1.07) for continental air masses, illustrating the presence of coarse mode and anthropogenic aerosols, respectively. Trajectory cluster analysis of 5 day back trajectories confirmed/augmented this classification. AOD for background marine and marine air mass types were consistent with ship-based (Maritime Aerosol Network) and island (AErosol RObotic NETwork) measurements, suggesting that CPT is a suitable site to monitor pristine conditions in the South Atlantic and Southern Oceans when 222Rn concentrations are < 100 mBq m-3.

  14. The Weight-Watch Program for Subdwarfs

    NASA Astrophysics Data System (ADS)

    Jao, Wei-Chun

    2011-10-01

    The mass-luminosity relation {MLR} is one of the most important map in stellar astronomy. The empirical MLR for dwarfs has been done for many years, but we do not even have enough low metallicity stars, the counterpart of dwarfs, for their MLR. This project of "Weight-Watch Program for Subdwarfs" is to establish such empirical MLR for low metallicity stars. We propose to use HST/FGS1r to finish mapping the visual orbit of one important benchmark low metallicity binary, G006-026. We resolved this double-lined spectroscopic binary in our Cycle 15 HST/FGS program. By combining the SB2 data and our single-epoch HST/FGS1r result, we have estimated their masses and visual orbit, but with errors in excess of 10%. By combining that effort with four additional orbits proposed in Cycle 19, we will reduce the mass errors to 5% {or less} and finish this star's "Weight-Watch program".

  15. Fire Watch Inspector Checklist A Fire Watch is an inspection conducted by DFSL staff to provide fire and smoke detection and emergency warning

    E-print Network

    Hill, Wendell T.

    14 Fire Watch Fire Watch Inspector Checklist A Fire Watch is an inspection conducted by DFSL staff to provide fire and smoke detection and emergency warning to occupants when a building's fire alarm or sprinkler system is non-operational. Fire Watch inspectors serve as a "human smoke detector" and notify 911

  16. Housing Coordinator Fire Watch Implementation Checklist A Fire Watch is an inspection conducted by DFSL staff in order to provide fire and smoke detection and emergency

    E-print Network

    Hill, Wendell T.

    12 Fire Watch Housing Coordinator Fire Watch Implementation Checklist A Fire Watch is an inspection conducted by DFSL staff in order to provide fire and smoke detection and emergency warning to occupants when a building's fire alarm or sprinkler system is non-operational. Fire Watch inspectors serve as a "human smoke

  17. A low speed two-dimensional study of flow separation on the GA(W)-1 airfoil with 30-percent chord Fowler flap

    NASA Technical Reports Server (NTRS)

    Seetharam, H. C.; Wentz, W. H., Jr.

    1977-01-01

    Measurements of flow fields with low speed turbulent boundary layers were made for the GA(W)-1 airfoil with a 0.30 c Fowler flap deflected 40 deg at angles of attack of 2.7 deg, 7.7 deg, and 12.8 deg, at a Reynolds number of 2.2 million, and a Mach number of 0.13. Details of velocity and pressure fields associated with the airfoil flap combination are presented for cases of narrow, optimum and wide slot gaps. Extensive flow field turbulence surveys were also conducted employing hot-film anemometry. For the optimum gap setting, the boundaries of the regions of flow reversal within the wake were determined by this technique for two angles of attack. Local skin friction distributions for the basic airfoil and the airfoil with flap (optimum gap) were obtained using the razor blade technique.

  18. Passenger Preferences for Whale Watching Tour Attributes and Payment

    E-print Network

    Passenger Preferences for Whale Watching Tour Attributes and Payment for Grey Whale Habitat of Resource Management (Planning) Report No. 553 Title of Project: Passenger Preferences for Whale Watching Tour Attributes and Payment for Grey Whale Habitat Protection: A Case Study in Tofino, B.C. Examining

  19. 47 CFR 80.310 - Watch required by voluntary vessels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Voluntary vessels not equipped with DSC must maintain a watch on 2182 kHz...Voluntary vessels equipped with VHF-DSC equipment must maintain a watch on 2182...Voluntary vessels equipped with MF-HF DSC equipment must have the radio turned...

  20. Gender Roles and Night-Sky Watching among College Students

    ERIC Educational Resources Information Center

    Kelly, William E.; McGee, Catherine M.

    2012-01-01

    The present study investigated the relationship between gender roles and night-sky watching in a sample of college students (N=161). The Bem Sex-Role Inventory (BSRI) and the Noctcaelador Inventory (NI) were used to investigate the differences between gender role groups for night-sky watching. The results supported the hypothesis that androgynous…

  1. Watching television by kids: How much and why?

    PubMed Central

    Morowatisharifabad, Mohammad Ali; Karimi, Masoud; Ghorbanzadeh, Fatemeh

    2015-01-01

    Introduction: Television (TV) viewing by children may be linked to a range of adverse health and behavioral outcomes. This study was aimed at examining the relationship between socioeconomic factors of families and TV watching behavior among 3–5 years old children in Ardakan, Yazd, Iran. Materials and Methods: In the cross-sectional study, mothers of 188 children (93 boys and 95 girls) between 3 and 5 years old completed a researcher-designed questionnaire. Data were analyzed by using SPSS, using bivariate correlations and t-test for independent samples. Results: The mean of TV viewing was 2.68 ± 1.6 h daily, ranging from 0 to 9 h. There were no statistically significant gender differences on the basis of daily TV watching. There were positive associations between the children's daily TV watching and age as well aschildren's daily TV watching and their mothers’ time spent on watching TV. Children who lived in houses with the yard and could use it as a playground watched less TV than did the children who lived in houses without the yard. Conclusion: The results suggest that health care professionals should be aware of the association between different socioeconomic status aspects of families, such as the children's and mothers’ time spent on watching TV and having a yard in the house in an attempt to develop effective strategies and interventions to prevent excess TV watching. PMID:26097850

  2. A SERVICE TO THE VICTORIAN COMMUNITY What is Flood Watch?

    E-print Network

    Greenslade, Diana

    A SERVICE TO THE VICTORIAN COMMUNITY What is Flood Watch? Flood Watch is a service provided by the Bureau of Meteorology to notify the Victorian community of the potential flood threat from a developing weather situation. It is an enhancement and replacement to the Flood Advice service previously provided

  3. Automatic Image Capturing and Processing for PetrolWatch

    E-print Network

    New South Wales, University of

    Automatic Image Capturing and Processing for PetrolWatch Yi Fei Dong1 Salil Kanhere1 Chun Tung Chou SOUTH WALES School of Computer Science and Engineering The University of New South Wales Sydney 2052 called PetrolWatch to collect fuel prices from camera images of road-side price board (billboard

  4. Frequency of College Students' Night-Sky Watching Behaviors

    ERIC Educational Resources Information Center

    Kelly, William E.; Kelly, Kathryn E.; Batey, Jason

    2006-01-01

    College students (N = 112) completed the Noctcaelador Inventory, a measure of psychological attachment to the night-sky, and estimated various night-sky watching related activities: frequency and duration of night-sky watching, astro-tourism, ownership of night-sky viewing equipment, and attendance of observatories or planetariums. The results…

  5. 76 FR 62760 - Grant of Authority for Subzone Status; LVMH Watch and Jewelry U.S.A., Inc.; (Watches, Jewelry...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-11

    ... facility of LVMH Watch and Jewelry U.S.A., Inc., located in Springfield, New Jersey (FTZ Docket 5-2011, filed 1-14-2011); Whereas, notice inviting public comment has been given in the Federal Register (76 FR...-Trade Zones Board Grant of Authority for Subzone Status; LVMH Watch and Jewelry U.S.A., Inc.;...

  6. Characteristics of aerosols and mass closure study at two WMO GAW regional background stations in eastern China

    NASA Astrophysics Data System (ADS)

    Yan, Peng; Zhang, Renjian; Huan, Ning; Zhou, Xiuji; Zhang, Yangmei; Zhou, Huaigang; Zhang, Leiming

    2012-12-01

    In the summer and winter of 2004 and 2005, size-segregated atmospheric aerosols were sampled with modified Andersen KA200 Multi-stage impactor at two regional background stations in the eastern China, the Shangdianzi station (SDZ) in the suburb of Beijing and the Lin'An station (LA) in the Yangtze river delta region, both are WMO Global Atmospheric Watch station, which represent the regional background of air pollutions of the two rapid developing economical zone of China, the Yangtze River Delta region (YRD) and Beijing-Tianjin region. The aerosol mass size distributions, ionic compositions, organic and elemental carbon (OC and EC), and elemental components were analyzed. The mass concentrations for TSP (total suspend particle), PM11 (aerodynamic diameter less than 11 ?m), and PM2.1 (aerodynamic diameter less than 2.1 ?m) at both sites showed obviously different between the winter and summer, with higher mass concentrations measured in the winter time. All seasonal mean mass concentrations of PM2.1 accounted for over 50% of PM11 at both sites. The aerosol mass closure study indicated that the total mass concentration reconstructed from the aerosol chemical composition agreed well with the measured gravimetric mass at the two stations. The fine aerosol particles at the two stations were composed mainly of sulfate and organic matter. In the summer, more than half of the PM2.1 mass was sulfate, suggesting a dominant contribution of secondary aerosol to the fine particles in these two regions. In the winter, the contribution of nitrate to the fine particles increased significantly due to the lower volatile losses under the cold weather. The proportions of soil type components in the PM2.1 showed similar magnitude in the winter and summer at Lin'An station but significant seasonal differences with higher fractions in the winter at Shangdianzi station. On average EC accounted for about 2%-6% of the fine particle mass (PM2.1) at both sites with proportionally lower EC values in the summer. The percentage of OM (Organic material) in TSP and PM2.1 showed less differences between winter and summer at Lin'An station, about 20%-30% in both TSP and PM2.1, however, the percentage at Shangdianzi station varied greatly from summer to winter, from 11% to 35% in PM2.1 and 12%-28% in TSP. Seasonal and geographical similarities and differences in PM2.1, PM11 and total suspended particles and comparison with previous studies at these regions are also discussed.

  7. Characterising Radon Emanations from Radium-Dial Watches

    NASA Astrophysics Data System (ADS)

    Crockett, Robin; Gillmore, Gavin

    2013-04-01

    Research during the latter half of 2011 has indicated that in addition to the hazard arising from the radium content of radium-dial watches, significant radon concentrations that exceed the UK Domestic and Workplace Action Levels of 200 Bq/m3 and 400 Bq/m3, respectively, can arise from watches stored in the built environment (1). In an extension to that earlier research, the radon emanations from the watches are being investigated in order to evaluate the radon hazard and the effective radium content of the watches. These radon measurements are made by placing the watches in a sealed chamber in a closed loop with a Durridge RAD7. We report here preliminary results from this ongoing investigation which suggest that radon emanation is not necessarily a straightforward function of radium content, as anticipated, but also depends on chamber temperature and humidity impacting upon watch-dependent factors such as design, construction, materials and wear-and-tear. Reference. 1. Gillmore G K, Crockett R G M, Denman A R, Flowers A, Harris R; Radium dial watches, a potentially hazardous legacy? Environment International. 45, 91-98. 2012. doi:10.1016/j.envint.2012.03.013.

  8. Global positioning system watches for estimating energy expenditure.

    PubMed

    Hongu, Nobuko; Orr, Barron J; Roe, Denise J; Reed, Rebecca G; Going, Scott B

    2013-11-01

    Global positioning system (GPS) watches have been introduced commercially, converting frequent measurements of time, location, speed (pace), and elevation into energy expenditure (EE) estimates. The purpose of this study was to compare EE estimates of 4 different GPS watches (Forerunner, Suunto, Polar, Adeo), at various walking speeds, with EE estimate from a triaxial accelerometer (RT3), which was used as a reference measure in this study. Sixteen healthy young adults completed the study. Participants wore 4 different GPS watches and an RT3 accelerometer and walked at 6-minute intervals on an outdoor track at 3 speeds (3, 5, and 7 km/hr). The statistical significance of differences in EE between the 3 watches was assessed using linear contrasts of the coefficients from the overall model. Reliability across trials for a given device was assessed using intraclass correlation coefficients as estimated in the mixed model. The GPS watches demonstrated lower reliability (intraclass correlation coefficient) across trials when compared with the RT3, particularly at the higher speed, 7 km/hr. Three GPS watches (Forerunner, Polar, and Suunto) significantly and consistently underestimated EE compared with the reference EE given by the RT3 accelerometer (average mean difference: Garmin, -50.5%; Polar, -41.7%; and Suunto, -41.7%; all p < 0.001). Results suggested that caution should be exercised when using commercial GPS watches to estimate EE in athletes during field-based testing and training. PMID:23439338

  9. Watching reality weight loss TV. The effects on body satisfaction, mood, and snack food consumption.

    PubMed

    Bourn, Rebecca; Prichard, Ivanka; Hutchinson, Amanda D; Wilson, Carlene

    2015-08-01

    The present study investigated the influence of a weight loss reality TV show on body satisfaction, mood and food consumption. Young Australian women (N?=?99) first completed baseline measures of state body satisfaction and mood. They were then randomly allocated to either a weight loss or a home renovation programme and were provided with snack foods during viewing. Post-measures included state body satisfaction, state mood and trait dietary restraint and snack food consumption. BMI moderated the relationship between condition and body satisfaction and mood. Larger women experienced less body satisfaction and less positive mood in response to the weight loss programme. Dietary restraint moderated the relationship between condition and food consumption. A greater percentage of women with lower dietary restraint ate in the control condition; whilst a greater percentage of women with higher dietary restraint ate food whilst watching the weight loss programme. These findings highlight the potential negative impact of weight-focused reality TV on mood, body satisfaction and snack food consumption among some women. PMID:25936290

  10. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  11. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  12. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  13. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  14. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  15. 76 FR 24504 - Agency Information Collection Activities: BioWatch Filter Holder Log

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... SECURITY Agency Information Collection Activities: BioWatch Filter Holder Log AGENCY: Department of... information from BioWatch jurisdictions. The BioWatch Program operates aerosol collector equipment in... representative of a BioWatch jurisdiction (either an employee, or a contractor) assigned responsibility...

  16. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 false Station log and radio watches. 80.1153 Section 80.1153...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153...

  17. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 false Station log and radio watches. 80.1153 Section 80.1153...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153...

  18. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...2010-10-01 false Station log and radio watches. 80.1153 Section 80.1153...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153...

  19. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 false Station log and radio watches. 80.1153 Section 80.1153...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153...

  20. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...2011-10-01 false Station log and radio watches. 80.1153 Section 80.1153...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153...

  1. Astronauts Sullivan and Ride synchronize their watches before liftoff

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Astronauts Kathryn Sullivan and Sally Ride synchronize their watches in the white room on the orbiter access arm before insertion into the orbiter crew compartment. This photo was done before liftoff of the Shuttle Challenger.

  2. Trial Watch: DNA vaccines for cancer therapy.

    PubMed

    Pol, Jonathan; Bloy, Norma; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Hervé Fridman, Wolf; Cremer, Isabelle; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    During the past 2 decades, the possibility that preparations capable of eliciting tumor-specific immune responses would mediate robust therapeutic effects in cancer patients has received renovated interest. In this context, several approaches to vaccinate cancer patients against their own malignancies have been conceived, including the administration of DNA constructs coding for one or more tumor-associated antigens (TAAs). Such DNA-based vaccines conceptually differ from other types of gene therapy in that they are not devised to directly kill cancer cells or sensitize them to the cytotoxic activity of a drug, but rather to elicit a tumor-specific immune response. In spite of an intense wave of preclinical development, the introduction of this immunotherapeutic paradigm into the clinical practice is facing difficulties. Indeed, while most DNA-based anticancer vaccines are well tolerated by cancer patients, they often fail to generate therapeutically relevant clinical responses. In this Trial Watch, we discuss the latest advances on the use of DNA-based vaccines in cancer therapy, discussing the literature that has been produced around this topic during the last 13 months as well as clinical studies that have been launched in the same time frame to assess the actual therapeutic potential of this intervention. PMID:24800178

  3. The experiment AIR-WATCH from SPACE

    NASA Astrophysics Data System (ADS)

    Scarsi, Livio

    1999-03-01

    The observation in the Cosmic Radiation of particles with energy above 1020eV and the foreseeable existence of neutrinos of comparable energy open a chapter of fundamental interest in Astro-particle Physics concerning their origin and propagation in the intergalactic space. The extremely low flux involved (order of 1 particle/year 1000km2 sr) on one side and the very low interaction cross section of neutrinos on the other, require detectors of exceptional dimensions. An adequate solution can be represented by exploiting the UV fluorescence induced by the ionizing radiation in the Earth atmosphere which offers a target with up to millions of km2 sr and 1013 tons. The primary Cosmic Ray particles, neutrinos and gammas can be detected through the luminescence associated to the giant showers (EAS) they give rise to by the cascade of interactions produced in the atmosphere. The observation is carried out from Space with detectors on board of a LEO (Low Earth Orbit) satellite. The experimental framework is outlined and a description is given of the AIR-WATCH from SPACE mission and of the observational strategy.

  4. Watch Dog detector for beam diagnostic in hadrontherapy application

    NASA Astrophysics Data System (ADS)

    Rojatti, E.; Bazzano, G.; Bosser, J.; Caldara, M.; Calvi, G.; Lanzavecchia, L.; Parravicini, A.; Pullia, M.; Viviani, C.

    2013-12-01

    The "Watch Dog" is a beam monitor designed for medical accelerators, that will be installed at the end of the CNAO (Centro Nazionale di Adroterapia Oncologica) extraction lines. Its main goal is to achieve a real time monitoring of the beam position during patient treatments; the system can generate an interlock signal in case the measured quantity is out of the nominal range. In this paper the Watch Dog is described, and preliminary tests are presented.

  5. "Walking and watching" in queer London: Sarah Waters' Tipping The Velvet and The Night Watch.

    PubMed

    Wood, Rachel

    2013-01-01

    This article argues that Sarah Waters' representation of London in her historical fictions Tipping the Velvet and The Night Watch is used to delineate the gendered bodies and sexual identities of her characters. A historical summary demonstrates that female masculinity was slowly mapped onto sexual identity between the 1880s and 1940s in Britain. The article argues that Waters' "inventive" use of this history allows her to question the construction of both historical and contemporary identifications. The way that Waters' characters are constricted and liberated by London's urban landscape demonstrates the spatial and temporal contingency of both gender and sexuality. PMID:23855943

  6. The modelling and assessment of whale-watching impacts

    USGS Publications Warehouse

    New, Leslie; Hall, Ailsa J.; Harcourt, Robert; Kaufman, Greg; Parsons, E.C.M.; Pearson, Heidi C.; Cosentino, A. Mel; Schick, Robert S

    2015-01-01

    In recent years there has been significant interest in modelling cumulative effects and the population consequences of individual changes in cetacean behaviour and physiology due to disturbance. One potential source of disturbance that has garnered particular interest is whale-watching. Though perceived as ‘green’ or eco-friendly tourism, there is evidence that whale-watching can result in statistically significant and biologically meaningful changes in cetacean behaviour, raising the question whether whale-watching is in fact a long term sustainable activity. However, an assessment of the impacts of whale-watching on cetaceans requires an understanding of the potential behavioural and physiological effects, data to effectively address the question and suitable modelling techniques. Here, we review the current state of knowledge on the viability of long-term whale-watching, as well as logistical limitations and potential opportunities. We conclude that an integrated, coordinated approach will be needed to further understanding of the possible effects of whale-watching on cetaceans.

  7. Trial watch: Peptide vaccines in cancer therapy.

    PubMed

    Vacchelli, Erika; Martins, Isabelle; Eggermont, Alexander; Fridman, Wolf Hervé; Galon, Jerome; Sautès-Fridman, Catherine; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2012-12-01

    Prophylactic vaccination constitutes one of the most prominent medical achievements of history. This concept was first demonstrated by the pioneer work of Edward Jenner, dating back to the late 1790s, after which an array of preparations that confer life-long protective immunity against several infectious agents has been developed. The ensuing implementation of nation-wide vaccination programs has de facto abated the incidence of dreadful diseases including rabies, typhoid, cholera and many others. Among all, the most impressive result of vaccination campaigns is surely represented by the eradication of natural smallpox infection, which was definitively certified by the WHO in 1980. The idea of employing vaccines as anticancer interventions was first theorized in the 1890s by Paul Ehrlich and William Coley. However, it soon became clear that while vaccination could be efficiently employed as a preventive measure against infectious agents, anticancer vaccines would have to (1) operate as therapeutic, rather than preventive, interventions (at least in the vast majority of settings), and (2) circumvent the fact that tumor cells often fail to elicit immune responses. During the past 30 y, along with the recognition that the immune system is not irresponsive to tumors (as it was initially thought) and that malignant cells express tumor-associated antigens whereby they can be discriminated from normal cells, considerable efforts have been dedicated to the development of anticancer vaccines. Some of these approaches, encompassing cell-based, DNA-based and purified component-based preparations, have already been shown to exert conspicuous anticancer effects in cohorts of patients affected by both hematological and solid malignancies. In this Trial Watch, we will summarize the results of recent clinical trials that have evaluated/are evaluating purified peptides or full-length proteins as therapeutic interventions against cancer. PMID:23264902

  8. Trial watch: DNA vaccines for cancer therapy.

    PubMed

    Senovilla, Laura; Vacchelli, Erika; Garcia, Pauline; Eggermont, Alexander; Fridman, Wolf Hervé; Galon, Jérôme; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-04-01

    The foundation of modern vaccinology dates back to the 1790s, when the English physician Edward Jenner uncovered the tremendous medical potential of prophylactic vaccination. Jenner's work ignited a wave of nationwide vaccination campaigns abating the incidence of multiple life-threatening infectious diseases and culminating with the eradication of natural smallpox virus, which was definitively certified by the WHO in 1980. The possibility of using vaccines against cancer was first proposed at the end of the 19th century by Paul Ehrlich and William Coley. However, it was not until the 1990s that such a hypothesis began to be intensively investigated, following the realization that the immune system is not completely unresponsive to tumors and that neoplastic cells express immunogenic tumor-associated antigens (TAAs). Nowadays, anticancer vaccines are rapidly moving from the bench to the bedside, and a few prophylactic and therapeutic preparations have already been approved by FDA for use in humans. In this setting, one interesting approach is constituted by DNA vaccines, i.e., TAA-encoding circularized DNA constructs, often of bacterial origin, that are delivered to patients as such or by means of specific vectors, including (but not limited to) liposomal preparations, nanoparticles, bacteria and viruses. The administration of DNA vaccines is most often performed via the intramuscular or subcutaneous route and is expected to cause (1) the endogenous synthesis of the TAA by myocytes and/or resident antigen-presenting cells; (2) the presentation of TAA-derived peptides on the cell surface, in association with MHC class I molecules; and (3) the activation of potentially therapeutic tumor-specific immune responses. In this Trial Watch, we will summarize the results of recent clinical trials that have evaluated/are evaluating DNA vaccines as therapeutic interventions against cancer. PMID:23734328

  9. Trial watch: Oncolytic viruses for cancer therapy.

    PubMed

    Vacchelli, Erika; Eggermont, Alexander; Sautès-Fridman, Catherine; Galon, Jérôme; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-06-01

    Oncolytic virotherapy is emerging as a promising approach for the treatment of several neoplasms. The term "oncolytic viruses" is generally employed to indicate naturally occurring or genetically engineered attenuated viral particles that cause the demise of malignant cells while sparing their non-transformed counterparts. From a conceptual standpoint, oncolytic viruses differ from so-called "oncotropic viruses" in that only the former are able to kill cancer cells, even though both display a preferential tropism for malignant tissues. Of note, such a specificity can originate at several different steps of the viral cycle, including the entry of virions (transductional specificity) as well as their intracellular survival and replication (post-transcriptional and transcriptional specificity). During the past two decades, a large array of replication-competent and replication-incompetent oncolytic viruses has been developed and engineered to express gene products that would specifically promote the death of infected (cancer) cells. However, contrarily to long-standing beliefs, the antineoplastic activity of oncolytic viruses is not a mere consequence of the cytopathic effect, i.e., the lethal outcome of an intense, productive viral infection, but rather involves the elicitation of an antitumor immune response. In line with this notion, oncolytic viruses genetically modified to drive the local production of immunostimulatory cytokines exert more robust therapeutic effects than their non-engineered counterparts. Moreover, the efficacy of oncolytic virotherapy is significantly improved by some extent of initial immunosuppression (facilitating viral replication and spread) followed by the administration of immunostimulatory molecules (boosting antitumor immune responses). In this Trial Watch, we will discuss the results of recent clinical trials that have evaluated/are evaluating the safety and antineoplastic potential of oncolytic virotherapy. PMID:23894720

  10. Making the Venus Concept Watch 1.0

    NASA Astrophysics Data System (ADS)

    Balint, Tibor S.; Melchiorri, Julian P.

    2014-08-01

    Over the past year we have celebrated the 50th anniversary of planetary exploration, which started with the Venus flyby of Mariner-2; and the 35th anniversary of the Pioneer-Venus multi-probe mission where one large and three small probes descended to the surface of Venus, encountering extreme environmental conditions. At the surface of Venus the temperature is about 460 °C, and the pressure is 92 bar, with a highly corrosive super-critical CO2 atmosphere. At a Venusian altitude of 50 km the pressure and temperature conditions are near Earth-like, but the clouds carry sulfuric acid droplets. Deep probe missions to Jupiter and Saturn, targeting the 100 bar pressure depth encounter similar pressure and temperature conditions as the Pioneer-Venus probes did. Mitigating these environments is highly challenging and requires special considerations for designs and materials. While assessing such space mission concepts, we have found that there is an overlap between the extreme environments in planetary atmospheres and the environments experienced by deep-sea explorers back on Earth. Consequently, the mitigation approaches could be also similar between planetary probes and diver watches. For example, both need to tolerate about 100 bar of pressure-although high temperatures are not factors on Earth. Mitigating these environments, the potential materials are: titanium for the probe and the watch housing; sapphire for the window and glass; resin impregnated woven carbon fiber for the aeroshell's thermal protection system and for the face of the watch; and nylon ribbon for the parachute and for the watch band. Planetary probes also utilize precision watches; thus there is yet another crosscutting functionality with diver watches. Our team, from the Innovation Design Engineering Program of the Royal College of Art, has designed and built a concept watch to commemorate these historical events, while highlighting advances in manufacturing processes over the past three to five decades, relevant to both future planetary mission designs and can be used to produce deep diver watches. In this paper we describe our design considerations; give a brief overview of the extreme environments these components would experience on both Venus and Earth; the manufacturing techniques and materials we used to build the Venus Watch; and its outreach potential to bring a distant concept of planetary exploration closer to Earth. We will also address lessons learned from this project and new ideas forward, for the next generation of this concept design.

  11. Cell scientist to watch - Maya Schuldiner.

    PubMed

    2015-11-15

    Maya Schuldiner pursued her PhD degree under the guidance of Prof. Nissim Benvenisty at the Hebrew University in Jerusalem. She carried out her postdoctoral training in the laboratory of Prof. Jonathan Weissman at the University of California, San Francisco, with support from the Human Frontiers Science Program and the Sandler Fellows Program. Since 2008, Maya has been running her own laboratory at the Weizmann Institute of Sciences in Rehovot, Israel. She received the Human Frontiers Science Program Career Development Award and the NIH Pathway to Independence Award, and she is a member of the EMBO Young Investigator programme and Faculty of 1000. Her current research interests are focused on unravelling novel functions of yeast proteins that are involved in organelle biology. PMID:26574503

  12. Design of programmable matter

    E-print Network

    Knaian, Ara N. (Ara Nerses), 1977-

    2008-01-01

    Programmable matter is a proposed digital material having computation, sensing, actuation, and display as continuous properties active over its whole extent. Programmable matter would have many exciting applications, like ...

  13. Programme Designs & Compulsory Modules

    E-print Network

    Harman, Neal.A.

    Programme Design 25 MSc Accounting/Finance Conversion Suite Programme Design Related documents Business Management & International Relations 1 Accounting & Finance BSc Accounting & Finance BSc Accounting BSc Finance Economics BSc Economics BSc Economics & Business BSc Economics & Finance BSc

  14. Programmable Neurocomputing Krste Asanovic

    E-print Network

    Asanovic, Krste

    Programmable Neurocomputing Krste Asanovi´c MIT Laboratory for Computer Science 200 Technology neurocomputers. Programmable neurocomputers(hereafter abbreviated to "neurocomputers") attempt to maintain most proces- sors for neural computation. This article first reviews the most significant neurocomputer

  15. 3-year chemical composition of free tropospheric PM1 at the Mt. Cimone GAW global station - South Europe - 2165 m a.s.l.

    NASA Astrophysics Data System (ADS)

    Carbone, Claudio; Decesari, Stefano; Paglione, Marco; Giulianelli, Lara; Rinaldi, Matteo; Marinoni, Angela; Cristofanelli, Paolo; Didiodato, Attilio; Bonasoni, Paolo; Fuzzi, Sandro; Facchini, Maria Cristina

    2014-04-01

    Nocturnal organic and inorganic chemical characterization of fine (PM1) aerosol was carried out at the GAW global high mountain station of Mt. Cimone (CMN), from January 2009 to December 2011, in the framework of the EU-EUSAAR and ACTRIS programs. The station is located at the summit of the Northern Italian Apennines (2165 m a.s.l.) overlooking the polluted Po river basin and is considered representative of background conditions for Southern Europe/Northern Mediterranean. The concentrations of carbonaceous and ionic aerosol follow a typical seasonal trend, with maxima during summer and minima during winter. The average PM1 mass apportioned by the chemical analyses ranged between 1.2 ± 0.68 ?g m-3 (winter) and 5.0 ± 2.7 ?g m-3 (summer), with ca. 80% and 60%, respectively, accounted for by organic matter, mainly water-soluble (yearly average WSOC/TC ratio 0.67 ± 0.18), the remainder taking the form of ammonium salts. The fine fraction turned out to be mostly neutralized by ammonia, with a slight tendency to acidity during colder months. This seasonal cycle can be explained by the interplay between the local/mesoscale (vertical) and large-scale (advective) circulations. From mid-spring to late summer, stable anticyclonic conditions and increased turbulent mixing in the lower troposphere, associated to the thermal mountain wind system, induce convective/thermal uplift of air masses from the Po Valley to CMN, strongly altering the free tropospheric aerosol features. Conversely, higher vertical stability at the low levels and variable transport patterns related to the passage of synoptic disturbances over Northern Italy, determine a weaker influence of vertical transport of pollution on aerosol composition, during midfall-winter. At CMN, the synoptic-scale circulation regimes presented four principal contributions: Mediterranean, Western Europe, continental Europe and Eastern Europe.

  16. GOES Weather Satellite Watches The Sun - Duration: 4 minutes, 47 seconds.

    NASA Video Gallery

    NASA satellites such as STEREO, SOHO, and SDO are dedicated to studying the sun. GOES is a weather satellite but also watches the sun constantly. Watch this video and learn why space weather data i...

  17. 47 CFR 80.148 - Watch on 156.8 MHz (Channel 16).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... vessels subject to the Bridge-to-Bridge Act and participating in a Vessel Traffic Service (VTS) system... Watches § 80.148 Watch on 156.8 MHz (Channel 16). Each compulsory vessel, while underway, must maintain...

  18. 47 CFR 80.148 - Watch on 156.8 MHz (Channel 16).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... subject to the Bridge-to-Bridge Act and participating in a Vessel Traffic Service (VTS) system when the... Watches § 80.148 Watch on 156.8 MHz (Channel 16). Each compulsory vessel, while underway, must maintain...

  19. 47 CFR 80.148 - Watch on 156.8 MHz (Channel 16).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... vessels subject to the Bridge-to-Bridge Act and participating in a Vessel Traffic Service (VTS) system... Watches § 80.148 Watch on 156.8 MHz (Channel 16). Each compulsory vessel, while underway, must maintain...

  20. 47 CFR 80.148 - Watch on 156.8 MHz (Channel 16).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... vessels subject to the Bridge-to-Bridge Act and participating in a Vessel Traffic Service (VTS) system... Watches § 80.148 Watch on 156.8 MHz (Channel 16). Each compulsory vessel, while underway, must maintain...

  1. Can positive matrix factorization help to understand patterns of organic trace gases at the continental Global Atmosphere Watch site Hohenpeissenberg?

    NASA Astrophysics Data System (ADS)

    Leuchner, M.; Gubo, S.; Schunk, C.; Wastl, C.; Kirchner, M.; Menzel, A.; Plass-Dülmer, C.

    2015-02-01

    From the rural Global Atmosphere Watch (GAW) site Hohenpeissenberg in the pre-alpine area of southern Germany, a data set of 24 C2-C8 non-methane hydrocarbons over a period of 7 years was analyzed. Receptor modeling was performed by positive matrix factorization (PMF) and the resulting factors were interpreted with respect to source profiles and photochemical aging. Differing from other studies, no direct source attribution was intended because, due to chemistry along transport, mass conservation from source to receptor is not given. However, at remote sites such as Hohenpeissenberg, the observed patterns of non-methane hydrocarbons can be derived from combinations of factors determined by PMF. A six-factor solution showed high stability and the most plausible results. In addition to a biogenic and a background factor of very stable compounds, four additional anthropogenic factors were resolved that could be divided into two short- and two long-lived patterns from evaporative sources/natural gas leakage and incomplete combustion processes. The volume or mass contribution at the site over the entire period was, in decreasing order, from the following factor categories: background, gas leakage and long-lived evaporative, residential heating and long-lived combustion, short-lived evaporative, short-lived combustion, and biogenic. The importance with respect to reactivity contribution was generally in reverse order, with the biogenic and the short-lived combustion factors contributing most. The seasonality of the factors was analyzed and compared to results of a simple box model using constant emissions and the photochemical decay calculated from the measured annual cycles of OH radicals and ozone. Two of the factors, short-lived combustion and gas leakage/long-lived evaporative, showed winter/summer ratios of about 9 and 7, respectively, as expected from constant source estimations. Contrarily, the short-lived evaporative emissions were about 3 times higher in summer than in winter, while residential heating/long-lived combustion emissions were about 2 times higher in winter than in summer.

  2. BY DANIEL CRESSEY oat trips to watch whales and dolphins

    E-print Network

    Gomulkiewicz, Richard

    with boats can hurt the animals,researchersaremoreconcernedabout effects such as animals failing to feed to whale- watching boats as they do to natural preda- tors, upping their speed and respir- ing more heavily1 . But whether this was a direct result of the boats is dif- ficult to pin down: Lusseau, who

  3. FROM WHALE HARVESTING TO WHALE WATCHING: TANGALOOMA 30 YEARS ON

    E-print Network

    FROM WHALE HARVESTING TO WHALE WATCHING: TANGALOOMA 30 YEARS ON Mark B. Orams and Paul H. Forestell Whale Foundation, Kealia Beach Plaza, 10 I N. Kihei Road, Kihei, Hawaii 96753, U.S.A. ABSTRACT Tourism on interactions with wild cetaceans. Tangalooma Whaling Station was located in South-east Queensland, Australia

  4. Motivation for Participation in Online Neighborhood Watch Communities: An Empirical

    E-print Network

    Shneiderman, Ben

    Motivation for Participation in Online Neighborhood Watch Communities: An Empirical Study Involving--This paper presents a three-part experiment de- signed to investigate the motivations of users of a community versions of an invitation email which differ by expressing one of four possible motivations for using

  5. FAU Study Finds Babies Learn To Speak By Watching Mouths

    E-print Network

    Fernandez, Eduardo

    FAU Study Finds Babies Learn To Speak By Watching Mouths January 17, 2012 11:34 PM Reporting most of their looks on the mouth region. "Our thinking is they're doing it because they're trying all. Now you'll focus on them looking at their mouth, like you'll want them to look at you more when

  6. Environmental Thought, the Language of Sustainability, and Digital Watches.

    ERIC Educational Resources Information Center

    Jickling, Bob

    2001-01-01

    Examines the limitations associated with the language of sustainability and their implications for environmental thinking. Explores what sustainability is not by using the idea of digital watches as a metaphor. Uses contemporary examples from advertising, curriculum development, and wildlife management to illustrate the central theme. (Author/SAH)

  7. Long Lake Whale Watch: Outdoor Education Comes Alive.

    ERIC Educational Resources Information Center

    Briggs, James N.

    1993-01-01

    Promotes the experiential learning benefits of outdoor education. Describes the experiences of students in grades 4-6 who planned, raised funds for, and participated in a field trip that included a visit to the New England Aquarium, a whale watch cruise, and camping on Cape Cod during a tropical storm. (LP)

  8. Litter Pollution, Level 2. Teacher Guide. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Waste Management, Richmond. Div. of Litter & Recycling.

    Operation Waste Watch is a series of seven sequential learning units which addresses the subject of litter control and solid waste management. Each unit may be used in a variety of ways, depending on the needs and schedules of individual schools, and may be incorporated into various social studies, science, language arts, health, mathematics, and…

  9. Watching MOOCs Together: Investigating Co-Located MOOC Study Groups

    ERIC Educational Resources Information Center

    Li, Nan; Verma, Himanshu; Skevi, Afroditi; Zufferey, Guillaume; Blom, Jan; Dillenbourg, Pierre

    2014-01-01

    Research suggests that massive open online course (MOOC) students prefer to study in groups, and that social facilitation within the study groups may render the learning of difficult concepts a pleasing experience. We report on a longitudinal study that investigates how co-located study groups watch and study MOOC videos together. The study was…

  10. Trash Treasures, Level 5. Teacher Guide. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Waste Management, Richmond. Div. of Litter & Recycling.

    Operation Waste Watch is a series of seven sequential learning units which addresses the subject of litter control and solid waste management. Each unit may be used in a variety of ways, depending on the needs and schedules of individual schools, and may be incorporated into various social studies, science, language arts, health, mathematics, and…

  11. Kathleen England watches her image transmitted to shuttle

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Kathleen England watches her image transmitted to her husband in the shuttle via the Shuttle Amateur Radio Experiment (SAREX). Looking on are amateur radio operators employed at JSC: Gil Carman (WA5NOM); Lou McFaddin (WSDIO), and Candy Torres (KASUKJ).

  12. Kathleen England watches her image transmitted to shuttle

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Kathleen England (foreground and on monitor) watches her image transmitted to her husband in the shuttle via the Shuttle Amateur Radio Experiment (SAREX). Looking on are amateur radio operators employed at JSC: Gil Carman (WA5NOM); Lou McFaddin (WSDIO), and Candy Torres (KASUKJ).

  13. Beginning Bird-Watching: New Programming Ideas Made More Affordable.

    ERIC Educational Resources Information Center

    Strauss, Mitchell

    1994-01-01

    Through corporate support, a bird-watching program was implemented at a summer camp for underprivileged New York City children. The program featured oversized flashcards containing color photos and facts about each bird, instruction on use of binoculars, and a hands-on experience in which campers used binoculars to identify bird cards placed in…

  14. Watch Out for Children: A Mothers' Statement to Advertisers.

    ERIC Educational Resources Information Center

    Institute for American Values, New York, NY.

    This report explains that all adults must watch out for all children, cautioning that marketing is harmful to children. Advertisers are aggressively targeting age groups that, until recently, have been considered off-limits and occupying more of children's psychic and physical space. The report presents a commitment by mothers to all children to…

  15. How Surfers Watch: Measuring audience response to video advertising online

    E-print Network

    Cortes, Corinna

    How Surfers Watch: Measuring audience response to video advertising online Sundar Dorai-Raj Google viewers through video advertising. Furthermore, we find that viewing behavior is even more effected by spe we measure ad abandonment. Section 3 describes methods we use to measure the effects due to partner

  16. Grid Watch: Mapping Blackouts with Smart Phones Noah Klugman

    E-print Network

    Dutta, Prabal

    Grid Watch: Mapping Blackouts with Smart Phones Noah Klugman , Javier Rosa , Pat Pannuto , Matthew General Terms Economics, Measurement, Reliability, Security Keywords Smart Grid, Power Monitoring into the power grid is via a cen- tralized network of utility owned, deployed, and controlled smart meters. While

  17. Watching and Feeling Proteins at Work Rede uitgesproken door

    E-print Network

    Schmidt, Thomas

    Watching and Feeling Proteins at Work Rede uitgesproken door Thomas Schmidt Bij de aanvaarding van molecuul met een perfect kristal: "Yet, compared with a biomolecule2 , they are rather plain and dull The Human Genome, Nature 15 Feb 2001 en Science 16 Feb 2001. #12;4 wellicht van de `biologische revolutie

  18. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Station log and radio watches. 80.1153 Section 80.1153 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153 Station log...

  19. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Station log and radio watches. 80.1153 Section 80.1153 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153 Station log...

  20. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Station log and radio watches. 80.1153 Section 80.1153 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153 Station log...

  1. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Station log and radio watches. 80.1153 Section 80.1153 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153 Station log...

  2. 47 CFR 80.1153 - Station log and radio watches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Station log and radio watches. 80.1153 Section 80.1153 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Voluntary Radio Installations General § 80.1153 Station log...

  3. Trash Trends, Level 3. Teacher Guide. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Waste Management, Richmond. Div. of Litter & Recycling.

    Operation Waste Watch is a series of seven sequential learning units which addresses the subject of litter control and solid waste management. Each unit may be used in a variety of ways, depending on the needs and schedules of individual schools, and may be incorporated into various social studies, science, language arts, health, mathematics, and…

  4. Sun Watching Lesson 4: Making a Sun Clock

    E-print Network

    Lawrence, Rick L.

    29 Sun Watching Lesson 4: Making a Sun Clock Lesson 4: Making a Sun Clock A major factor contributing toward our concept of time is based on the apparent motion of the Sun. In this activity, students will construct Pocket Sun Clocks. They are challenged to determine the correct orientation needed for the Sun

  5. Framework for a Technology-Watch Relay Station

    ERIC Educational Resources Information Center

    Stokes, C. A.; Palmer, P. J.

    2004-01-01

    At the centre of the PRIME Faraday Partnership's Technology Watch service is a growing series of technology and market reviews for managers and engineers in small and medium-sized enterprises (SMEs) producing "smart" products. Its aim is to help them maintain their awareness of new technologies and markets and thereby seize opportunities to…

  6. Losing Sleep to Watch the Night-Sky: The Relationship between Sleep-Length and Noctcaelador

    ERIC Educational Resources Information Center

    Kelly, William E.; Rose, Callie

    2005-01-01

    For most of history, humans have been watching the night-sky (Hawkins, 1983). Historically, individuals have watched the night-sky for aesthetic appreciation and to gain insights and knowledge (Brecher & Feirtag, 1979). Despite the long history of night-sky watching among humans and the apparent importance of the behavior to large groups of…

  7. 47 CFR 80.148 - Watch on 156.8 MHz (Channel 16).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch on 156.8 MHz (Channel 16). 80.148 Section 80.148 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... Watches § 80.148 Watch on 156.8 MHz (Channel 16). Each compulsory vessel, while underway, must maintain...

  8. 47 CFR 80.303 - Watch on 156.800 MHz (Channel 16).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch on 156.800 MHz (Channel 16). 80.303 Section 80.303 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... Watches § 80.303 Watch on 156.800 MHz (Channel 16). (a) During its hours of operation, each coast...

  9. Watching Together: Integrating Text Chat with Video Justin D. Weisz, Sara Kiesler, Hui Zhang,

    E-print Network

    Kiesler, Sara

    Watching Together: Integrating Text Chat with Video Justin D. Weisz, Sara Kiesler, Hui Zhang of an active social experience is unclear: both chatting and watching video require attention, and may the activity of chatting while watching video online. We examine how groups of friends and strangers interact

  10. 76 FR 42130 - Agency Information Collection Activities: BioWatch Filter Holder Log

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... collection request (ICR) in the Federal Register on May 2, 2011 at 76 FR 24504, for a 60-day public comment... SECURITY Agency Information Collection Activities: BioWatch Filter Holder Log AGENCY: Department of... information from BioWatch jurisdictions. The BioWatch Program operates aerosol collector equipment...

  11. The Global Economic Impact of Manta Ray Watching Tourism

    PubMed Central

    O’Malley, Mary P.; Lee-Brooks, Katie; Medd, Hannah B.

    2013-01-01

    As manta rays face increased threats from targeted and bycatch fisheries, manta ray watching tourism, if managed properly, may present an attractive economic alternative to consumptive use of these species. Both species in the genus Manta (Manta alfredi and Manta birostris) are classified by the International Union for the Conservation of Nature Red List as species Vulnerable to extinction in the wild, and are considered unsustainable as fisheries resources due to their conservative life history characteristics, which considerably reduce their ability to recover population numbers when depleted. Utilising dive operator surveys, Internet research, and a literature review, this study provides the first global estimate of the direct economic impact of manta ray watching tourism and examines the potential socio-economic benefits of non-consumptive manta ray watching operations relative to consumptive use of manta rays as a fishery resource. In the 23 countries in which manta ray watching operations meeting our criteria were identified, we estimated direct revenue to dive operators from manta ray dives and snorkels at over US$73 million annually and direct economic impact, including associated tourism expenditures, of US$140 million annually. Ten countries account for almost 93% of the global revenue estimate, specifically Japan, Indonesia, the Maldives, Mozambique, Thailand, Australia, Mexico, United States, Federated States of Micronesia and Palau. In many of the areas where directed fisheries for manta rays are known to occur, these activities overlap with manta ray tourism sites or the migratory range of the mantas on which these sites depend, and are likely to be unsustainable and detrimental to manta ray watching tourism. PMID:23741450

  12. Long-term surface ozone variability at Mt. Cimone WMO/GAW global station (2165 m a.s.l., Italy)

    NASA Astrophysics Data System (ADS)

    Cristofanelli, P.; Scheel, H.-E.; Steinbacher, M.; Saliba, M.; Azzopardi, F.; Ellul, R.; Fröhlich, M.; Tositti, L.; Brattich, E.; Maione, M.; Calzolari, F.; Duchi, R.; Landi, T. C.; Marinoni, A.; Bonasoni, P.

    2015-01-01

    The Mediterranean basin represents a hot spot area for short-term O3 distribution and anthropogenic contributions to it. This is why we analysed in this work the surface O3 variability observed at Mt. Cimone WMO/GAW global station (CMN, 44°12? N, 10°42? E, 2165 m a.s.l., Italy) from 1991 to 2011. The measurements performed at this mountain observatory represent the longest surface O3 record at a baseline site in the Mediterranean basin. Monthly O3 averages at CMN show a typical seasonal cycle characterised by a winter minimum and a spring - summer maxima. The shape of the mean annual variation of O3 is well comparable with those observed at other four baseline sites in the Alps and in the Mediterranean region: Jungfraujoch - Swiss Alps, Sonnblick - Austrian Alps, Mt. Krvavec- Slovenia and Giordan Lightouse - Island of Gozo, Malta. In general, O3 levels at CMN show higher values during warm months, which is likely to be related both to vertical transport of polluted air-masses at regional and continental scales and to enhanced photochemistry. Here, we also investigate the influence of specific atmospheric processes (i.e. the occurrence of heat-waves, North Atlantic Oscillation, thermal transport of air-masses from the regional PBL and stratospheric intrusions) in affecting O3 variability at CMN. Overall, a significant positive (95% confidence level) linear trend in monthly O3 mole fraction was observed over the period 1991-2011 (0.21 ± 0.10 nmol/mol yr-1) while no trend (-0.02 ± 0.12 nmol/mol yr-1) was detected for the 1996-2011, when measurements were carried out by an homogeneous experimental set-up. On a seasonal basis, a positive trend has been observed for 1996-2011 (0.34 ± 0.32 nmol/mol yr-1) only for spring. Significant decreases of the seasonal O3 growth-rates have been detected at CMN during 1991-2011 from winter to spring and only for summer during 1996-2011.

  13. Globe Watch. Teachers' Guide for Globe Watch IV: Mexico, Canada, Finland, Japan, the Arms Race, the Iran-Iraq War.

    ERIC Educational Resources Information Center

    Turner, Ginny

    To enhance the use of the Globe Watch IV public television series, produced jointly by Hampden-Sydney College (Virginia) and the University of North Carolina Center for Public Television, each lesson in this guide provides: (1) a statement of the objective of the program; (2) a synopsis of the issue discussed; (3) background information; (4) brief…

  14. The European Fusion Programme

    SciTech Connect

    Antidormi, R.; Bartlett, D.; Bruhns, H.

    2004-03-15

    The long-term objective of the European fusion programme is the harnessing of the power of fusion to help meet mankind's future energy needs.This paper describes the current research programme, the unique organisational character of the fusion programme, and European and world-wide co-operation. The future evolution of the programme as part of the European Research Area and the developments currently taking place in preparation for the possible construction of ITER, the next major step towards the realisation of fusion power, are discussed.

  15. Analysing the Types of TV Programmes Viewed by Children from Different Socio-Economic Strata Based on Their Self-Report in the Turkish Context

    ERIC Educational Resources Information Center

    Kabadayi, Abdulkadir

    2006-01-01

    This research investigated the amount of time that children from different socio-economic strata spend watching television per week and whether there was a difference among children from low, middle and upper socio-economic strata with regard to viewing programme types, including action adventure, news and information, competitions, sports,…

  16. Conceptualizing Programme Evaluation

    ERIC Educational Resources Information Center

    Hassan, Salochana

    2013-01-01

    The main thrust of this paper deals with the conceptualization of theory-driven evaluation pertaining to a tutor training programme. Conceptualization of evaluation, in this case, is an integration between a conceptualization model as well as a theoretical framework in the form of activity theory. Existing examples of frameworks of programme

  17. Undergraduate Education programmes

    E-print Network

    Molinari, Marc

    and Maths (C or above) + personal statement #12;Why Education/Education and Psychology in Southampton? · BScUndergraduate Education programmes BSc (Hons) Education BSc (Hons) Education & Psychology (BPS accreditation) Dr Kiki Messiou, Programme Director #12;What are we looking for? BSc Education · A levels ­ ABB

  18. Watch-wearing as a marker of conscientiousness

    PubMed Central

    Jenkins, Rob

    2015-01-01

    Several aspects of an individual’s appearance have been shown to predict personality and related behaviour. While some of these cues are grounded in biology (e.g., the human face), other aspects of a person’s appearance can be actively controlled (e.g., clothing). In this paper, we consider a common fashion accessory, the wristwatch. In an exploratory sample (N > 100) and a confirmatory sample (N > 600), we compared big-five personality traits between individuals who do or do not regularly wear a standard wristwatch. Significantly higher levels of conscientiousness were observed in participants who wore a watch. In a third study (N = 85), watch wearers arrived significantly earlier to appointments in comparison to controls. These results are discussed in relation to enclothed cognition and the rise of wearable technology including smartwatches. PMID:26334540

  19. SOTANCP3 Scientific Programme

    NASA Astrophysics Data System (ADS)

    2014-12-01

    The programme for the 3rd International Workshop on "State of the Art in Nuclear Cluster Physics" which was held at the KGU (Kanto Gakuin University) Kannai Media Center (8th floor of Yokohoma Media Business Center (YMBC))

  20. WORLD WATER ASSESSMENT PROGRAMME

    EPA Science Inventory

    The overall objective of the World Water Assessment Programme is to support the building of global security - food, environment, economic, social and political security -- through an integrated comprehensive freshwater assessment.The specific objectives within the assessment pr...

  1. Programmable matter by folding

    E-print Network

    Wood, R. J.

    Programmable matter is a material whose properties can be programmed to achieve specific shapes or stiffnesses upon command. This concept requires constituent elements to interact and rearrange intelligently in order to ...

  2. Job title Bioinformatics programmer

    E-print Network

    Pompeu Fabra, Universitat

    on the minimum requirements Applicants should have a University degree in Biology, Chemistry, Physics Job title Bioinformatics programmer Job description A technician position is available immediately at Eyras' Research Group at the Pompeu Fabra University, PRBB

  3. Programmable Logic Application Notes

    NASA Technical Reports Server (NTRS)

    Katz, Richard

    1998-01-01

    This column will be provided each quarter as a source for reliability, radiation results, NASA capabilities, and other information on programmable logic devices and related applications. This quarter's column will include some announcements and some recent radiation test results and evaluations of interest. Specifically, the following topics will be covered: the Military and Aerospace Applications of Programmable Devices and Technologies Conference to be held at GSFC in September, 1998, proton test results, heavy ion test results, and some total dose results.

  4. ESR response of watch glasses to proton beams

    NASA Astrophysics Data System (ADS)

    Longo, A.; Basile, S.; Brai, M.; Marrale, M.; Tranchina, L.

    2010-09-01

    In this paper we have analyzed the electron spin resonance (ESR) signal of watch glasses irradiated with ?60 MeV proton beams in the dose range between 1 and 105 Gy. The composition of samples expressed in oxides weight percentages has been obtained carrying out X-ray fluorescence spectrometry (XRF) measurements. The ESR signal has been studied in terms of its dependence on microwave power and modulation field in order to choose the optimal recording parameters. The dependence of the radioinduced signal on the exposure dose has been investigated. A numerical procedure aimed at improving the sensitivity in the low dose range has been developed.

  5. The Canadian Ozone Watch and UV-B advisory programs

    NASA Technical Reports Server (NTRS)

    Kerr, J. B.; Mcelroy, C. T.; Tarasick, D. W.; Wardle, D. I.

    1994-01-01

    The Ozone Watch, initiated in March, 1992, is a weekly bulletin describing the state of the ozone layer over Canada. The UV-B advisory program, which started in May, 1992, produces daily forecasts of clear-sky UV-B radiation. The forecast procedures use daily ozone measurements from the eight-station monitoring network, the output from the Canadian operational forecast model and a UV-B algorithm based on three years of spectral UV-B measurements with the Brewer spectrophotometer.

  6. Watch and wait approach to rectal cancer: A review

    PubMed Central

    Pozo, Marcos E; Fang, Sandy H

    2015-01-01

    In 2014, there were an estimated 136800 new cases of colorectal cancer, making it the most common gastrointestinal malignancy. It is the second leading cause of cancer death in both men and women in the United States and over one-third of newly diagnosed patients have stage III (node-positive) disease. For stage II and III colorectal cancer patients, the mainstay of curative therapy is neoadjuvant therapy, followed by radical surgical resection of the rectum. However, the consequences of a proctectomy, either by low anterior resection or abdominoperineal resection, can lead to very extensive comorbidities, such as the need for a permanent colostomy, fecal incontinence, sexual and urinary dysfunction, and even mortality. Recently, trends of complete regression of the rectal cancer after neoadjuvant chemoradiation therapy have been confirmed by clinical and radiographic evaluation-this is known as complete clinical response (cCR). The “watch and wait” approach was first proposed by Dr. Angelita Habr-Gama in Brazil in 2009. Those patients with cCR are followed with close surveillance physical examinations, endoscopy, and imaging. Here, we review management of rectal cancer, the development of the “watch and wait” approach and its outcomes. PMID:26649153

  7. 47 CFR 80.147 - Watch on 2182 kHz.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch on 2182 kHz. 80.147 Section 80.147 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... 2182 kHz. Ship stations must maintain a watch on 2182 kHz as prescribed by § 80.304....

  8. 47 CFR 80.147 - Watch on 2182 kHz.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch on 2182 kHz. 80.147 Section 80.147 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... 2182 kHz. Ship stations must maintain a watch on 2182 kHz as prescribed by § 80.304....

  9. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...false Watch required by the Great Lakes Radio Agreement. 80.308 Section 80.308...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES...308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  10. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...false Watch required by the Great Lakes Radio Agreement. 80.308 Section 80.308...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES...308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  11. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...false Watch required by the Great Lakes Radio Agreement. 80.308 Section 80.308...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES...308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  12. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...false Watch required by the Great Lakes Radio Agreement. 80.308 Section 80.308...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES...308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  13. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...false Watch required by the Great Lakes Radio Agreement. 80.308 Section 80.308...COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES...308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  14. From Whale Hunting to Whale Watching in Tonga: A Sustainable Future?

    E-print Network

    From Whale Hunting to Whale Watching in Tonga: A Sustainable Future? Mark B. Orams Centre reputation as a whale-watching destination. The pro-whaling organisation, the World Council of Whalers, with some local people, has, however, been actively promoting a resumption of whaling in Tonga. This study

  15. 47 CFR 80.148 - Watch on 156.8 MHz (Channel 16).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...general communications using digital selective calling and the watch on 156.800 MHz is provided so that ships not fitted with DSC will be able to call GMDSS ships, thus providing a link between GMDSS and non-GMDSS compliant ships. The watch on...

  16. Incidental Foreign-Language Acquisition by Children Watching Subtitled Television Programs

    ERIC Educational Resources Information Center

    Ina, Lekkai

    2014-01-01

    Series of international studies have shown that subtitled television programs provide a rich context for foreign language acquisition. This study investigated whether incidental language acquisition occurs from watching a television program with/without subtitles. Children in the experimental conditions watch: (a) a 15 minute snapshot of a well…

  17. 47 CFR 80.147 - Watch on 2182 kHz.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch on 2182 kHz. 80.147 Section 80.147 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... 2182 kHz. Ship stations must maintain a watch on 2182 kHz as prescribed by § 80.304....

  18. 47 CFR 80.147 - Watch on 2182 kHz.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch on 2182 kHz. 80.147 Section 80.147 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE... 2182 kHz. Ship stations must maintain a watch on 2182 kHz as prescribed by § 80.304....

  19. Watching Together: Integrating Conversation with Video Justin D. Weisz*, Sara Kiesler*, Hui Zhang*,

    E-print Network

    increasingly popular, and new video streaming technologies have the potential to transform video-watching from attentional resources. Anyone who has attempted to watch a movie while others are talking knows of the effort important to HCI for several reasons. First, HCI has a history of interest in the human capacity

  20. September 30, 2010 Watch the Web Town Hall on UC Benefits

    E-print Network

    Leistikow, Bruce N.

    September 30, 2010 Watch the Web Town Hall on UC Benefits Those who missed last Friday's live university issues can still watch an archived tape of the Web Town Hall on UC Benefits. The event Anderson. Panelists tried to answer as many questions as they could from both the live and web audience

  1. 33 CFR 80.155 - Watch Hill, RI to Montauk Point, NY.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Atlantic Coast § 80.155 Watch Hill, RI to Montauk Point, NY. (a) A line drawn from Watch Hill Light to East Point on Fishers Island. (b) A line drawn from Race Point to Race Rock Light; thence to Little Gull Island Light thence to East...

  2. Realizing Outdoor Independent Learning with a Butterfly-Watching Mobile Learning System

    ERIC Educational Resources Information Center

    Chen, Yuh-Shyan; Kao, Tai-Chien; Sheu, Jang-Ping

    2005-01-01

    In this article, we describe the development of a mobile butterfly-watching learning (BWL) system to realize outdoor independent learning for mobile learners. The mobile butterfly-watching learning system was designed in a wireless mobile ad-hoc learning environment. This is first result to provide a cognitive tool with supporting the independent…

  3. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Vessel Traffic Services (VTS) system as required or recommended by the U.S. Coast Guard, when an...-Bridge Act and participating in a Vessel Traffic Services (VTS) system when a watch is maintained on both... authorized traffic. The VHF watch must be maintained at the vessel's steering station actually in use by...

  4. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Vessel Traffic Services (VTS) system as required or recommended by the U.S. Coast Guard, when an... such station is not being used for authorized traffic. The VHF watch must be maintained at the vessel's... Act and participating in a Vessel Traffic Services (VTS) system when an efficient listening watch...

  5. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Vessel Traffic Services (VTS) system as required or recommended by the U.S. Coast Guard, when an... such station is not being used for authorized traffic. The VHF watch must be maintained at the vessel's... Act and participating in a Vessel Traffic Services (VTS) system when an efficient listening watch...

  6. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Vessel Traffic Services (VTS) system as required or recommended by the U.S. Coast Guard, when an...-Bridge Act and participating in a Vessel Traffic Services (VTS) system when a watch is maintained on both... authorized traffic. The VHF watch must be maintained at the vessel's steering station actually in use by...

  7. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Vessel Traffic Services (VTS) system as required or recommended by the U.S. Coast Guard, when an... such station is not being used for authorized traffic. The VHF watch must be maintained at the vessel's... Act and participating in a Vessel Traffic Services (VTS) system when an efficient listening watch...

  8. International Halley watch amateur observers' manual for scientific comet studies. Part 1: Methods

    NASA Technical Reports Server (NTRS)

    Edberg, S. J.

    1983-01-01

    The International Halley Watch is described as well as comets and observing techniques. Information on periodic Comet Halley's apparition for its 1986 perihelion passage is provided. Instructions are given for observation projects valuable to the International Halley Watch in six areas of study: (1) visual observations; (2) photography; (3) astrometry; (4) spectroscopic observations; (5) photoelectric photometry; and (6) meteor observations.

  9. eWatch: A Wearable Sensor and Notification Platform Uwe Maurer1

    E-print Network

    Rowe, Anthony

    eWatch: A Wearable Sensor and Notification Platform Uwe Maurer1 , Anthony Rowe2 , Asim Smailagic3, Technische Universität München, Germany Abstract The eWatch is a wearable sensing, notification, and com a wearable comput- ing platform, a description of the power aware hardware and software architectures

  10. Media Richness and Social Norms in the Choice to Attend Lectures or to Watch Them Online

    ERIC Educational Resources Information Center

    Bassili, John N.

    2008-01-01

    Lectures in a large psychology course were taped and posted online where they could be viewed by streaming video. All students in the course had the option to attend lectures or watch them online, a choice that could be exercised on a lecture-by-lecture basis. The proportion of lectures watched online revealed that students chose between…

  11. 75 FR 10463 - Office of Insular Affairs; Allocation of Duty-Exemptions for Calendar Year 2010 for Watch...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... Changes in Watch, Watch Movement and Jewelry Program for the U.S. Insular Possessions, 65 FR 8048... producer allocation Belair Quartz, Inc 500,000 The balance of the units allocated to the USVI is...

  12. Overview of Training Programmes Autumn 2013 Project/ Training programme Description

    E-print Network

    Aickelin, Uwe

    Overview of Training Programmes Autumn 2013 Project/ Training programme Description Advanced Port Talbot and Carmarthenshire County Borough Council. Advanced Sustainable Manufacturing Technologies. Welsh Printing and Coating Centre Providing support in all aspects of the printing and coating industry

  13. Watching as an ordinary affect: Care and mothers’ preemption of injury in child supervision

    PubMed Central

    Dao, Amy

    2014-01-01

    As unintentional injuries continue to be the leading cause of hospitalization and death for toddlers between the ages of 1 and 4, the Centers for Disease Control has argued that child supervision is a key factor in reducing these injuries and fatalities. This article focuses on the affective relationships in the concept of supervision and practice of watching as an injury prevention method. Three parts frame our argument. First, we describe how watching is an ordinary affect. Second, as part of the ethos of caring, watching is embedded in a temporal frame of anticipation and gives rise to an affectsphere of watching and to a parents’ subjectivity as ‘good’ or ‘bad’ supervisors. Third, these affective relationships generate seemingly contradictory outcomes wherein children are expected to gain independence and experience injury. The affective qualities of watching provide a critique of the individualizing forces of supervision and an analysis of subjectivities generated by gender and class. PMID:25114724

  14. Development of ultrasonic motor and application to silent alarm analog quartz watch

    NASA Astrophysics Data System (ADS)

    Kasuga, Masao; Satoh, Takashi; Hirotomi, Jun; Kawata, Masayuki

    An ultrasonic motor was developed for use in new generation watches and portable information devices. This motor shows promise as a new principle actuator. Measuring 10 mm in diameter and 4.5 mm thick, this ultrasonic motor is the world's smallest for practical use. Powered by a single lithium coin battery, this motor is expected to be applied to a broad range of miniature devices, including watches. The structure of the motor makes it possible to reduce its size and drive frequency. This motor was used to incorporate a silent alarm into an analog quartz watch. Unlike conventional electronic alarm watches, an eccentric weight rotates intermittently at high speed generating gentle vibration which notifies the wearer. The silent alarm analog quartz watch which incorporates the new ultrasonic motor, as well as the influence of design parameters on the performance of the ultrasonic motor, are described.

  15. MEDICINE SOCIETY PROGRAMME Acknowledgements

    E-print Network

    Rambaut, Andrew

    research 21 3.1|The concept of `therapeutic cloning' 23 3.2|Terminology 23 3.3|Judgements about using Cloning The Wellcome Trust Medicine in Society Programme A Social Research Study #12;Contents 2 one explored 8 1.6|The sample 9 1.7|Recruitment 10 1.8|Briefing the researchers 10 Summary 4 twoCloning

  16. Tribal health programme.

    PubMed

    Kuriyan, J

    1982-01-01

    In June 1978, the Department of Social Welfare, Government of Maharashtra, commissioned the Centre for Development Studies and Activities (CDSA), Pune, to prepare an Action Programme for the Improvement of Health in the Tribal Areas of Maharashtra. The following is the brief report submitted by CDSA. PMID:10260956

  17. Programmable physiological infusion

    NASA Technical Reports Server (NTRS)

    Howard, W. H.; Young, D. R.; Adachi, R. R. (inventors)

    1974-01-01

    A programmable physiological infusion device and method are provided wherein a program source, such as a paper tape, is used to actuate an infusion pump in accordance with a desired program. The system is particularly applicable for dispensing calcium in a variety of waveforms.

  18. NSEPMI 2014 Technical Programme

    E-print Network

    Dharmadhikari, C. V.

    for drug delivery applications) 12.15 ­ 12.30 PM Soumen Karmakar (Phenomenological perspectives Processing and Industrial Applications 2014 Technical Programme Day 1 (Thursday) Date 13/02/2014 SESSION 1 of particle nucleation and growth in transferred arc thermal plasma system) 03.30 - 04.00PM TEA SESSION 4

  19. Work Programme, 2014

    ERIC Educational Resources Information Center

    Cedefop - European Centre for the Development of Vocational Training, 2014

    2014-01-01

    Cedefop's work programme 2014 constitutes an ambitious attempt to preserve its core activities, respond to new requests and ensure previous quality standards while respecting resource constraints. Nevertheless, it also reflects the risk that the Centre's ability to deliver its mission and increasing demands may be affected by further budgetary…

  20. Developing Online Doctoral Programmes

    ERIC Educational Resources Information Center

    Chipere, Ngoni

    2015-01-01

    The objectives of the study were to identify best practices in online doctoral programming and to synthesise these practices into a framework for developing online doctoral programmes. The field of online doctoral studies is nascent and presents challenges for conventional forms of literature review. The literature was therefore reviewed using a…

  1. Programmation Web Introduction

    E-print Network

    Belaïd, Abdel

    1 Programmation Web Introduction #12;2 Introduction 10 séances ­ 1 h cours + 1h TD Notes 2 absences non justifiées) ­ Note finale : (2DS+TP)/3 ~TD #12;3 Objectif Créer une application Web;5 Introduction C'est quoi une application web ? ­ Une application dont l'infrastructure d'exécution est

  2. Computer Programmer/Analyst.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This publication contains 25 subjects appropriate for use in a competency list for the occupation of computer programmer/analyst, 1 of 12 occupations within the business/computer technologies cluster. Each unit consists of a number of competencies; a list of competency builders is provided for each competency. Titles of the 25 units are as…

  3. MSc Programme Construction Management

    E-print Network

    Langendoen, Koen

    in Civil Engineering. I teach Construction Law and Planning Law as a part of the CME programme. This provides students with an introduction to the following topics: Building Contract Law, Procurement Law for exciting jobs in today's demanding construction markets. I take tremendous pleasure in teaching law to CME

  4. Programmable Logic Application Notes

    NASA Technical Reports Server (NTRS)

    Katz, Richard

    2000-01-01

    This column will be provided each quarter as a source for reliability, radiation results, NASA capabilities, and other information on programmable logic devices and related applications. This quarter will start a series of notes concentrating on analysis techniques with this issues section discussing worst-case analysis requirements.

  5. Programme, Abstracts, Presentations & Proceedings

    E-print Network

    Programme, Abstracts, Presentations & Proceedings 24th IAEA Fusion Energy Conference October 8 be authorized to attend, but without the right to take part in the proceedings. Scientists interested of their own countries, in most cases the Ministry of Foreign Affairs or national atomic energy authority. IAEA

  6. Resource Engineering MSc Programme

    E-print Network

    Langendoen, Koen

    to recover minerals and mineral ores from the earth, how these materials can be processed and how useable: In this specialisation, you will learn about the processing of mineral resources and secondary materials. Material life a programme that covers every aspect of the life cycle of mineral resources. In this track, you will learn how

  7. Programmable Logic Application Notes

    NASA Technical Reports Server (NTRS)

    Katz, Richard; Day, John H. (Technical Monitor)

    2001-01-01

    This report will be provided each quarter as a source for reliability, radiation results, NASA capabilities, and other information on programmable logic devices and related applications. This quarter will continue a series of notes concentrating on analysis techniques with this issue's section discussing the use of Root-Sum-Square calculations for digital delays.

  8. Backgrounder: The MAB Programme.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Office of Public Information.

    The Man and the Biosphere Programme (MAB) was launched in November 1971 under the auspices of Unesco. Its aim is to help to develop scientific knowledge with a view to the rational management and conservation of natural resources, to train qualified personnel in this field, and to disseminate the knowledge acquired both to the decision-makers and…

  9. programme in MATHEMATICS AND PHYSICS

    E-print Network

    ?umer, Slobodan

    CODEX Doctoral programme in MATHEMATICS AND PHYSICS Ljubljana, August 2008 #12;FMF UL, Phys.....................................................................................4 3. Fundamental objectives of the doctoral study programme mathematics and physics and general.................................................................................12 Subprogramme Physics............................................................................12

  10. Watching paint dry; more exciting than it seems.

    PubMed

    van der Kooij, Hanne M; Sprakel, Joris

    2015-08-28

    With an ever-increasing demand for sustainable alternatives to solvent-borne coatings and paints, the pressure to develop aqueous alternatives that match or exceed the performance of their traditional counterparts rises. A crucial step in this sustainability challenge for the years to come is to arrive at a deep, and complete, understanding of how aqueous paints dry and form their final protective films. As it turns out, this is no minor challenge. Yet, understanding drying and film formation is a prototypical soft matter problem at heart, displaying a rich variety of complex non-equilibrium phenomena that are waiting to be understood. Watching paint dry is far from the boring activity the saying suggests. PMID:26205733

  11. Master programme in Ecology & Evolution

    E-print Network

    Richner, Heinz

    Master programme in Ecology & Evolution Jointly organized by the Institute of Ecology and Evolution at the University of Bern Selected specialisation within the MSc programme in Ecology & Evolution Programme start and conservation Plant ecology Behaviour Evolution autumn semester spring semester year: 20.. 3 semester 4 semester

  12. Future Programmes Scientific Steering Committee

    E-print Network

    Page Foreword Future Programmes Scientific Steering Committee Scientific Policy Statement Programme, because of the quality of people and science at the Institute, and a responsibility, to the UK community the Scientific Steering Committee which is at the heart of the peer review process for selecting programmes; from

  13. PROGRAMME GROUP RESEARCH UPDATE: Biodiversity indicators &

    E-print Network

    1 PROGRAMME GROUP RESEARCH UPDATE: Biodiversity indicators & knowledge management programme group Introduction Duncan Ray The programme group Biodiversity Indicators and Knowledge Management (BIKM) was established by the merger of the Biodiversity Indicators & Evaluation Programme and the Decision Support

  14. Is Watching Television a Realistic Leisure Option for People with Dementia?

    PubMed Central

    Gústafsdóttir, Margrét

    2015-01-01

    Background Watching television is a common leisure activity, not least among older people. However, watching television may become difficult when it is disturbed by symptoms of dementia. Method A total of 284 questionnaires were handed out to relatives of people with dementia in Iceland, in the Memory Clinic of the University Hospital and in specialized units for people with dementia (6 day-care units and 8 units within nursing homes). The response rate was just below 58%. Results Watching television was shown to play a less important role in the course of the daily life of people with dementia as soon as the symptoms of the disease became evident, and it increasingly became less relevant. So, this previous leisure activity left an ever-growing void of time to fill. However, watching television may provide an important social context for contact and togetherness during the progress of the disease, as watching television with someone close to them was important for the individuals with dementia. Conclusion It is not a viable option for people with dementia to watch television on their own, but they may enjoy watching television while sharing this activity with a person close to them. This may even provide quality time. PMID:25941531

  15. Punch Card Programmable Microfluidics

    PubMed Central

    Korir, George; Prakash, Manu

    2015-01-01

    Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external components has remained elusive. Combining the idea of punch card programming with arbitrary fluid control, here we describe a self-contained, hand-crank powered, multiplex and robust programmable microfluidic platform. A paper tape encodes information as a series of punched holes. A mechanical reader/actuator reads these paper tapes and correspondingly executes operations onto a microfluidic chip coupled to the platform in a plug-and-play fashion. Enabled by the complexity of codes that can be represented by a series of holes in punched paper tapes, we demonstrate independent control of 15 on-chip pumps with enhanced mixing, normally-closed valves and a novel on-demand impact-based droplet generator. We demonstrate robustness of operation by encoding a string of characters representing the word “PUNCHCARD MICROFLUIDICS” using the droplet generator. Multiplexing is demonstrated by implementing an example colorimetric water quality assays for pH, ammonia, nitrite and nitrate content in different water samples. With its portable and robust design, low cost and ease-of-use, we envision punch card programmable microfluidics will bring complex control of microfluidic chips into field-based applications in low-resource settings and in the hands of children around the world. PMID:25738834

  16. Punch card programmable microfluidics.

    PubMed

    Korir, George; Prakash, Manu

    2015-01-01

    Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external components has remained elusive. Combining the idea of punch card programming with arbitrary fluid control, here we describe a self-contained, hand-crank powered, multiplex and robust programmable microfluidic platform. A paper tape encodes information as a series of punched holes. A mechanical reader/actuator reads these paper tapes and correspondingly executes operations onto a microfluidic chip coupled to the platform in a plug-and-play fashion. Enabled by the complexity of codes that can be represented by a series of holes in punched paper tapes, we demonstrate independent control of 15 on-chip pumps with enhanced mixing, normally-closed valves and a novel on-demand impact-based droplet generator. We demonstrate robustness of operation by encoding a string of characters representing the word "PUNCHCARD MICROFLUIDICS" using the droplet generator. Multiplexing is demonstrated by implementing an example colorimetric water quality assays for pH, ammonia, nitrite and nitrate content in different water samples. With its portable and robust design, low cost and ease-of-use, we envision punch card programmable microfluidics will bring complex control of microfluidic chips into field-based applications in low-resource settings and in the hands of children around the world. PMID:25738834

  17. The Ulysses Supplement to the GRANAT/WATCH Catalog of Cosmic Gamma-Ray Bursts

    E-print Network

    K. Hurley; N. Lund; S. Brandt; C. Barat; T. Cline; R. Sunyaev; O. Terekhov; A. Kuznetsov; S. Sazonov; A. Castro-Tirado

    2000-01-03

    We present 3rd interplanetary network (IPN) localization data for 56 gamma-ray bursts in the GRANAT/ WATCH catalog which occurred between 1990 November and 1994 September. These localizations are obtained by triangulation using various combinations of spacecraft in the IPN, which consisted of Ulysses, BATSE, Pioneer Venus Orbiter (PVO), Mars Observer (MO), WATCH, and PHEBUS. The intersections of the triangulation annuli with the WATCH error circles produce error boxes with areas as small as 16 sq. arcmin., reducing the sizes of the error circles by up to a factor of 800.

  18. Programmable matter by folding

    PubMed Central

    Hawkes, E.; An, B.; Benbernou, N. M.; Tanaka, H.; Kim, S.; Demaine, E. D.; Rus, D.; Wood, R. J.

    2010-01-01

    Programmable matter is a material whose properties can be programmed to achieve specific shapes or stiffnesses upon command. This concept requires constituent elements to interact and rearrange intelligently in order to meet the goal. This paper considers achieving programmable sheets that can form themselves in different shapes autonomously by folding. Past approaches to creating transforming machines have been limited by the small feature sizes, the large number of components, and the associated complexity of communication among the units. We seek to mitigate these difficulties through the unique concept of self-folding origami with universal crease patterns. This approach exploits a single sheet composed of interconnected triangular sections. The sheet is able to fold into a set of predetermined shapes using embedded actuation. To implement this self-folding origami concept, we have developed a scalable end-to-end planning and fabrication process. Given a set of desired objects, the system computes an optimized design for a single sheet and multiple controllers to achieve each of the desired objects. The material, called programmable matter by folding, is an example of a system capable of achieving multiple shapes for multiple functions. PMID:20616049

  19. P2.2 A LOOK AT THE TORNADO REPORT AND WATCH CLIMATOLOGY FOR THE CONTINENTAL UNITED STATES FROM 1986-2005

    E-print Network

    P2.2 A LOOK AT THE TORNADO REPORT AND WATCH CLIMATOLOGY FOR THE CONTINENTAL UNITED STATES FROM 1986 * This study is an update to the Imy et al (1998) tornado watch climatology. Tornado watch issuances are examined for the two 10-year periods 1986-1995 and 1996-2005. Tornado watches typically cover roughly 65

  20. Safety evaluation of interim stabilization of non-stabilized single-shell watch list tanks

    SciTech Connect

    Stahl, S.M.

    1994-12-30

    The report provides a summation of the status of safety issues associated with interim stabilization of Watch List SSTs (organic, ferrocyanide, and flammable gas), as extracted from recent safety analyses, including the Tank Farms Accelerated Safety Analysis efforts.

  1. 75 FR 61164 - Credit Watch Termination Initiative Termination of Origination Approval Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ..., 1999 HUD published a notice (64 FR 26769), on its procedures for terminating Origination Approval... URBAN DEVELOPMENT Credit Watch Termination Initiative Termination of Origination Approval Agreements..., Office of Housing, Department of Housing and Urban Development, 451 Seventh Street, SW., Room...

  2. Barbara Morgan and Christa McAuliffe watch the STS 61-A launch of Challenger

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Barbara R. Morgan and Sharon Christa McAuliffe (right) watch the STS 61-A launch of Challenger at Kennedy Space Center's Launch complex 39 (25293); McAuliffe turns to camera as STS 61-A launch progresses (25294).

  3. 76 FR 42130 - Agency Information Collection Activities: BioWatch Filter Holder Log

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ...Information Collection Activities: BioWatch Filter Holder Log AGENCY: Department of Homeland...responsibility for installing and removing filters from aerosol collection devices and transportation...laboratories for sample analysis. A standard filter log form is completed for each...

  4. 76 FR 24504 - Agency Information Collection Activities: BioWatch Filter Holder Log

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ...Information Collection Activities: BioWatch Filter Holder Log AGENCY: Department of Homeland...responsibility for installing and removing filters from aerosol collection devices and transportation...laboratories for sample analysis. A standard filter log form is completed for each...

  5. How Things Work: A Spinning Top, Lenz's Law and Electric Watches.

    ERIC Educational Resources Information Center

    Crane, H. Richard, Ed.

    1984-01-01

    Provides a physics explanation for a toy top driven by a magnet. Draws parallels to electric watches which use balance wheels with small permanent magnet mounts on them and having the coils mounted at one side. (JM)

  6. 33 CFR 157.420 - Vessel specific watch policy and procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain Tank Vessels Without Double Hulls Carrying Petroleum Oils § 157.420 Vessel specific watch policy and...

  7. 33 CFR 157.420 - Vessel specific watch policy and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain Tank Vessels Without Double Hulls Carrying Petroleum Oils § 157.420 Vessel specific watch policy and...

  8. 33 CFR 157.420 - Vessel specific watch policy and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain Tank Vessels Without Double Hulls Carrying Petroleum Oils § 157.420 Vessel specific watch policy and...

  9. 33 CFR 157.420 - Vessel specific watch policy and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain Tank Vessels Without Double Hulls Carrying Petroleum Oils § 157.420 Vessel specific watch policy and...

  10. 33 CFR 157.420 - Vessel specific watch policy and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain Tank Vessels Without Double Hulls Carrying Petroleum Oils § 157.420 Vessel specific watch policy and...

  11. 76 FR 4126 - Credit Watch Termination Initiative Termination of Origination Approval Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ..., 1999 HUD published a notice (64 FR 26769), on its procedures for terminating Origination Approval... URBAN DEVELOPMENT Credit Watch Termination Initiative Termination of Origination Approval Agreements..., Office of Housing, Department of Housing and Urban Development, 451 Seventh Street, SW., Room...

  12. Children infer affiliative and status relations from watching others imitate.

    PubMed

    Over, Harriet; Carpenter, Malinda

    2015-11-01

    We investigated whether young children are able to infer affiliative relations and relative status from observing others' imitative interactions. Children watched videos showing one individual imitating another and were asked about the relationship between those individuals. Experiment 1 showed that 5-year-olds assume that individuals imitate people they like. Experiment 2 showed that children of the same age assume that an individual who imitates is relatively lower in status. Thus, although there are many advantages to imitating others, there may also be reputational costs. Younger children, 4-year-olds, did not reliably make either inference. Taken together, these experiments demonstrate that imitation conveys valuable information about third party relationships and that, at least by the age of 5, children are able to use this information in order to infer who is allied with whom and who is dominant over whom. In doing so, they add a new dimension to our understanding of the role of imitation in human social life. PMID:25529928

  13. Trial Watch: Chemotherapy with immunogenic cell death inducers.

    PubMed

    Vacchelli, Erika; Aranda, Fernando; Eggermont, Alexander; Galon, Jérôme; Sautès-Fridman, Catherine; Cremer, Isabelle; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    Accumulating evidence suggests that the clinical efficacy of selected anticancer drugs, including conventional chemotherapeutics as well as targeted anticancer agents, originates (at least in part) from their ability to elicit a novel or reinstate a pre-existing tumor-specific immune response. One of the mechanisms whereby chemotherapy can stimulate the immune system to recognize and destroy malignant cells is commonly known as immunogenic cell death (ICD). Cancer cells succumbing to ICD are de facto converted into an anticancer vaccine and as such elicit an adaptive immune response. Several common chemotherapeutics share the ability of triggering ICD, as demonstrated in vaccination experiments relying on immunocompetent mice and syngeneic cancer cells. A large number of ongoing clinical trials involve such ICD inducers, often (but not always) as they are part of the gold standard therapeutic approach against specific neoplasms. In this Trial Watch, we summarize the latest advances on the use of cyclophosphamide, doxorubicin, epirubicin, oxaliplatin, and mitoxantrone in cancer patients, discussing high-impact studies that have been published during the last 13 months as well as clinical trials that have been initiated in the same period to assess the antineoplastic profile of these immunogenic drugs as off-label therapeutic interventions. PMID:24800173

  14. Trial Watch: Toll-like receptor agonists in oncological indications.

    PubMed

    Aranda, Fernando; Vacchelli, Erika; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Sautès-Fridman, Catherine; Cremer, Isabelle; Henrik Ter Meulen, Jan; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    Toll-like receptors (TLRs) are an evolutionarily conserved group of enzymatically inactive, single membrane-spanning proteins that recognize a wide panel of exogenous and endogenous danger signals. Besides constituting a crucial component of the innate immune response to bacterial and viral pathogens, TLRs appear to play a major role in anticancer immunosurveillance. In line with this notion, several natural and synthetic TLR ligands have been intensively investigated for their ability to boost tumor-targeting immune responses elicited by a variety of immunotherapeutic and chemotherapeutic interventions. Three of these agents are currently approved by the US Food and Drug Administration (FDA) or equivalent regulatory agencies for use in cancer patients: the so-called bacillus Calmette-Guérin, monophosphoryl lipid A, and imiquimod. However, the number of clinical trials testing the therapeutic potential of both FDA-approved and experimental TLR agonists in cancer patients is stably decreasing, suggesting that drug developers and oncologists are refocusing their interest on alternative immunostimulatory agents. Here, we summarize recent findings on the use of TLR agonists in cancer patients and discuss how the clinical evaluation of FDA-approved and experimental TLR ligands has evolved since the publication of our first Trial Watch dealing with this topic. PMID:25083332

  15. Trial Watch: Adoptive cell transfer for anticancer immunotherapy.

    PubMed

    Aranda, Fernando; Vacchelli, Erika; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Hervé Fridman, Wolf; Cremer, Isabelle; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    The expression "adoptive cell transfer" (ACT) is commonly employed to indicate an immunotherapeutic regimen involving the isolation of autologous blood-borne or tumor-infiltrating lymphocytes, their selection/expansion/activation ex vivo, and their reinfusion into the patient, most often in the context of lymphodepleting pre-conditioning and in combination with immunostimulatory treatments. Optionally, the cellular material for ACT is genetically manipulated before expansion to (1) target specific tumor-associated antigens; (2) endogenously express immunostimulatory molecules; and/or (3) persist for long periods upon reinfusion. Consistent efforts have been dedicated at the amelioration of this immunotherapeutic regimen throughout the past decade, resulting in the establishment of ever more efficient and safer ACT protocols. Accordingly, the number of clinical trials testing ACT in oncological indications does not cease to increase. In this Trial Watch, we summarize recent developments in this exciting area of research, covering both high-impact studies that have been published during the last 12 months and clinical trials that have been launched in the same period to evaluate the safety and therapeutic potential of ACT in cancer patients. PMID:25050207

  16. Toughening elastomers with sacrificial bonds and watching them break

    NASA Astrophysics Data System (ADS)

    Creton, Costantino

    2014-03-01

    Most unfilled elastomers are relatively brittle, in particular when the average molecular weight between crosslinks is lower than the average molecular weight between entanglements. We created a new class of tough elastomers by introducing isotropically prestretched chains inside ordinary acrylic elastomers by successive swelling and polymerization steps. These new materials combine a high entanglement density with a densely crosslinked structure reaching elastic moduli of 4 MPa and fracture strength of 25 MPa. The highly prestretched chains are the minority in the material and can break in the bulk of the material before catastrophic failure occurs, increasing the toughness of the material by two orders of magnitude up to 5 kJ/m2. To investigate the details of the toughening mechanism we introduced specific sacrificial dioxetane bonds in the prestretched chains that emit light when they break. In uniaxial extension cyclic experiments, we checked that the light emission corresponded exactly and quantitatively to the energy dissipation in each cycle demonstrating that short chains break first and long chains later. We then watched crack propagation in notched samples and mapped spatially the location of bond breakage ahead of the crack tip before and during propagation. This new toughening mechanism for elastomers creates superentangled rubbers and is ideally suited to overcome the trade-off between toughness and stiffness of ordinary elastomers. We gratefully acknowledge funding from DSM Ahead

  17. Confined quantum Zeno dynamics of a watched atomic arrow

    NASA Astrophysics Data System (ADS)

    Signoles, Adrien; Facon, Adrien; Grosso, Dorian; Dotsenko, Igor; Haroche, Serge; Raimond, Jean-Michel; Brune, Michel; Gleyzes, Sébastien

    2014-10-01

    In a quantum world, a watched arrow never moves. This is the quantum Zeno effect. Repeatedly asking a quantum system `are you still in your initial state?' blocks its coherent evolution through measurement back-action. Quantum Zeno dynamics (QZD; refs , ) gives more freedom to the system. Instead of pinning it to a single state, it sets a border in its evolution space. Repeatedly asking the system `are you beyond the border?' makes this limit impenetrable. As the border can be designed by choosing the measured observable, QZD allows one to dynamically tailor the system's Hilbert space. Recent proposals, particularly in the cavity quantum electrodynamics context, highlight the interest of QZD for quantum state engineering tasks, which are the key to quantum-enabled technologies and quantum information processing. We report the observation of QZD in the 51-dimensional Hilbert space of a large angular momentum J = 25. Continuous selective interrogation limits the evolution of this angular momentum to an adjustable multi-dimensional subspace. This confined dynamics leads to the production of non-classical `Schrödinger cat' states, quantum superpositions of angular momenta pointing in different directions. These states are promising for sensitive metrology of electric and magnetic fields. This QZD approach could also be generalized to cavity and circuit quantum electrodynamics experiments by replacing the angular momentum with a photonic harmonic oscillator.

  18. Effect of Watching 3-Dimensional Television on Refractive Error in Children

    PubMed Central

    Kim, Seung-Hyun; Choi, Yong-Min; Han, Ji-Yoon; Nam, Gi-Tae; You, Eun-Joo; Cho, Yoonae A.

    2015-01-01

    Purpose To investigate the effect of watching 3-dimensional (3D) television (TV) on refractive error in children. Methods Sixty healthy volunteers, aged 6 to 12 years, without any ocular abnormalities other than refractive error were recruited for this study. They watched 3D TV for 50 minutes at a viewing distance of 2.8 meters. The image disparity of the 3D contents was from -1 to 1 degree. Refractive errors were measured both before and immediately after watching TV and were rechecked after a 10-minute rest period. The refractive errors before and after watching TV were compared. The amount of refractive change was also compared between myopes and controls. The refractive error of the participants who showed a myopic shift immediately after watching TV were compared across each time point to assure that the myopic shift persisted after a 10-minute rest. Results The mean age of the participants was 9.23 ± 1.75 years. The baseline manifest refractive error was -1.70 ± 1.79 (-5.50 to +1.25) diopters. The refractive errors immediately after watching and after a 10-minute rest were -1.75 ± 1.85 and -1.69 ± 1.80 diopters, respectively, which were not different from the baseline values. Myopic participants (34 participants), whose spherical equivalent was worse than -0.75 diopters, also did not show any significant refractive change after watching 3D TV. A myopic shift was observed in 31 participants with a mean score of 0.29 ± 0.23 diopters, which resolved after a 10-minute rest. Conclusions Watching properly made 3D content on a 3D TV for 50 minutes with a 10-minute intermission at more than 2.8 meters of viewing distance did not affect the refractive error of children. PMID:25646061

  19. A programmable Fortran preprocessor

    SciTech Connect

    Rosing, M.

    1995-06-01

    A programmable Fortran preprocessor is described. It allows users to define compile time operations that can examine and modify the source tree before it is compiled with a traditional compiler. This intermediate step allows the definition of routines and operations that adapt to the context in which they are used. Context sensitive operations increase the flexibility of abstractions that can be built without degrading efficiency, as compared to using traditional run time based abstractions such as libraries or objects. The preprocessor is described briefly along with an example of how it is used to add CMFortran array operations to Fortran77. Other preprocessors that have been implemented are also briefly described.

  20. NASCAP programmer's reference manual

    NASA Technical Reports Server (NTRS)

    Mandell, M. J.; Stannard, P. R.; Katz, I.

    1993-01-01

    The NASA Charging Analyzer Program (NASCAP) is a computer program designed to model the electrostatic charging of complicated three-dimensional objects, both in a test tank and at geosynchronous altitudes. This document is a programmer's reference manual and user's guide. It is designed as a reference to experienced users of the code, as well as an introduction to its use for beginners. All of the many capabilities of NASCAP are covered in detail, together with examples of their use. These include the definition of objects, plasma environments, potential calculations, particle emission and detection simulations, and charging analysis.

  1. Flexible programmable logic module

    DOEpatents

    Robertson, Perry J. (Albuquerque, NM); Hutchinson, Robert L. (Albuquerque, NM); Pierson, Lyndon G. (Albuquerque, NM)

    2001-01-01

    The circuit module of this invention is a VME board containing a plurality of programmable logic devices (PLDs), a controlled impedance clock tree, and interconnecting buses. The PLDs are arranged to permit systolic processing of a problem by offering wide data buses and a plurality of processing nodes. The board contains a clock reference and clock distribution tree that can drive each of the PLDs with two critically timed clock references. External clock references can be used to drive additional circuit modules all operating from the same synchronous clock reference.

  2. Hybridized Electromagnetic-Triboelectric Nanogenerator for a Self-Powered Electronic Watch.

    PubMed

    Quan, Ting; Wang, Xue; Wang, Zhong Lin; Yang, Ya

    2015-12-22

    We report a hybridized nanogenerator including a triboelectric nanogenerator (TENG) and six electromagnetic generators (EMGs) that can effectively scavenge biomechanical energy for sustainably powering an electronic watch. Triggered by the natural motions of the wearer's wrist, a magnetic ball at the center in an acrylic box with coils on each side will collide with the walls, resulting in outputs from both the EMGs and the TENG. By using the hybridized nanogenerator to harvest the biomechanical energy, the electronic watch can be continuously powered under different motion types of the wearer's wrist, where the best approach is to charge a 100 ?F capacitor in 39 s to maintain the continuous operation of the watch for 456 s. To increase the working time of the watch further, a homemade Li-ion battery has been utilized as the energy storage unit for realizing the continuous working of the watch for about 218 min by using the hybridized nanogenerator to charge the battery within 32 min. This work will provide the opportunities for developing a nanogenerator-based built-in power source for self-powered wearable electronics such as an electronic watch. PMID:26565597

  3. Watching you watching you

    E-print Network

    Nagura, Hideji

    1982-01-01

    This thesis consists of four parts. Part one is a written dialogue in which I respond to the words and the thoughts of the photographer, Diane Arbus. Through responding to Arbus' thoughts, I had hoped to make clear my own ...

  4. CAMAC modular programmable function generator

    SciTech Connect

    Turner, G.W.; Suehiro, S.; Hendricks, R.W.

    1980-12-01

    A CAMAC modular programmable function generator has been developed. The device contains a 1024 word by 12-bit memory, a 12-bit digital-to-analog converter with a 600 ns settling time, an 18-bit programmable frequency register, and two programmable trigger output registers. The trigger registers can produce programmed output logic transitions at various (binary) points in the output function curve, and are used to synchronize various other data acquisition devices with the function curve.

  5. Electrically-programmable diffraction grating

    DOEpatents

    Ricco, Antonio J. (Albuquerque, NM); Butler, Michael A. (Albuquerque, NM); Sinclair, Michael B. (Albuquerque, NM); Senturia, Stephen D. (Brookline, MA)

    1998-01-01

    An electrically-programmable diffraction grating. The programmable grating includes a substrate having a plurality of electrodes formed thereon and a moveable grating element above each of the electrodes. The grating elements are electrostatically programmable to form a diffraction grating for diffracting an incident beam of light as it is reflected from the upper surfaces of the grating elements. The programmable diffraction grating, formed by a micromachining process, has applications for optical information processing (e.g. optical correlators and computers), for multiplexing and demultiplexing a plurality of light beams of different wavelengths (e.g. for optical fiber communications), and for forming spectrometers (e.g. correlation and scanning spectrometers).

  6. Copernicus Earth observation programme

    NASA Astrophysics Data System (ADS)

    Žlebir, Silvo

    European Earth observation program Copernicus is an EU-wide programme that integrates satellite data, in-situ data and modeling to provide user-focused information services to support policymakers, researchers, businesses and citizens. Land monitoring service and Emergency service are fully operational already, Atmosphere monitoring service and Marine environment monitoring service are preoperational and will become fully operational in the following year, while Climate change service and Security service are in an earlier development phase. New series of a number of dedicated satellite missions will be launched in the following years, operated by the European Space Agency and EUMETSAT, starting with Sentinel 1A satellite early this year. Ground based, air-borne and sea-borne in-situ data are provided by different international networks and organizations, EU member states networks etc. European Union is devoting a particular attention to secure a sustainable long-term operational provision of the services. Copernicus is also stated as a European Union’s most important contribution to Global Earth Observation System of Systems (GEOSS). The status and the recent development of the Copernicus programme will be presented, together with its future perspective. As Copernicus services have already demonstrated their usability and effectiveness, some interesting cases of their deployment will be presented. Copernicus free and open data policy, supported by a recently adopted EU legislative act, will also be presented.

  7. Programme Specification Title of programme: MSc Genomic Medicine

    E-print Network

    Huang, Xun

    1 Programme Specification Title of programme: MSc Genomic Medicine This specification provides Medicine Interim Exit awards Postgraduate Diploma in Genomic Medicine / Postgraduate Certificate in Genomic Medicine/ Postgraduate Certificate in the Principles of Genomic Medicine. FHEQ level of final award 7 UCAS

  8. Trial watch: Dendritic cell-based interventions for cancer therapy.

    PubMed

    Vacchelli, Erika; Vitale, Ilio; Eggermont, Alexander; Fridman, Wolf Hervé; Fu?íková, Jitka; Cremer, Isabelle; Galon, Jérôme; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-10-01

    Dendritic cells (DCs) occupy a privileged position at the interface between innate and adaptive immunity, orchestrating a large panel of responses to both physiological and pathological cues. In particular, whereas the presentation of antigens by immature DCs generally results in the development of immunological tolerance, mature DCs are capable of priming robust, and hence therapeutically relevant, adaptive immune responses. In line with this notion, functional defects in the DC compartment have been shown to etiologically contribute to pathological conditions including (but perhaps not limited to) infectious diseases, allergic and autoimmune disorders, graft rejection and cancer. Thus, the possibility of harnessing the elevated immunological potential of DCs for anticancer therapy has attracted considerable interest from both researchers and clinicians over the last decade. Alongside, several methods have been developed not only to isolate DCs from cancer patients, expand them, load them with tumor-associated antigens and hence generate highly immunogenic clinical grade infusion products, but also to directly target DCs in vivo. This intense experimental effort has culminated in 2010 with the approval by the US FDA of a DC-based preparation (sipuleucel-T, Provenge(®)) for the treatment of asymptomatic or minimally symptomatic metastatic castration-refractory prostate cancer. As an update to the latest Trial Watch dealing with this exciting field of research (October 2012), here we summarize recent advances in DC-based anticancer regimens, covering both high-impact studies that have been published during the last 13 mo and clinical trials that have been launched in the same period to assess the antineoplastic potential of this variant of cellular immunotherapy. PMID:24286020

  9. Trial Watch: Adoptive cell transfer for anticancer immunotherapy.

    PubMed

    Vacchelli, Erika; Eggermont, Alexander; Fridman, Wolf Hervé; Galon, Jérôme; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-05-01

    Adoptive cell transfer (ACT) represents a prominent form of immunotherapy against malignant diseases. ACT is conceptually distinct from dendritic cell-based approaches (which de facto constitute cellular vaccines) and allogeneic transplantation (which can be employed for the therapy of hematopoietic tumors) as it involves the isolation of autologous lymphocytes exhibiting antitumor activity, their expansion/activation ex vivo and their reintroduction into the patient. Re-infusion is most often performed in the context of lymphodepleting regimens (to minimize immunosuppression by host cells) and combined with immunostimulatory interventions, such as the administration of Toll-like receptor agonists. Autologous cells that are suitable for ACT protocols can be isolated from tumor-infiltrating lymphocytes or generated by engineering their circulating counterparts for the expression of transgenic tumor-specific T-cell receptors. Importantly, lymphocytes can be genetically modified prior to re-infusion for increasing their persistence in vivo, boosting antitumor responses and minimizing side effects. Moreover, recent data indicate that exhausted antitumor T lymphocytes may be rejuvenated in vitro by exposing them to specific cytokine cocktails, a strategy that might considerably improve the clinical success of ACT. Following up the Trial Watch that we published on this topic in the third issue of OncoImmunology (May 2012), here we summarize the latest developments in ACT-related research, covering both high-impact studies that have been published during the last 13 months and clinical trials that have been initiated in the same period to assess the antineoplastic profile of this form of cellular immunotherapy. PMID:23762803

  10. Promoting interdisciplinary education - the Vienna Doctoral Programme on Water Resource Systems

    NASA Astrophysics Data System (ADS)

    Blöschl, G.; Carr, G.; Bucher, C.; Farnleitner, A. H.; Rechberger, H.; Wagner, W.; Zessner, M.

    2012-02-01

    The Vienna Doctoral Programme on Water Resource Systems (DK-WRS) is a programme that aims to educate students in interdisciplinary water science through cutting edge research at an international level. It is funded by the Austrian Science Fund and designed to run over a period of 12 yr during which 80 doctoral students are anticipated to graduate. This paper reports on our experiences of setting up and implementing the Programme. We identify three challenges: integrating the disciplines, maintaining depth in an interdisciplinary programme, and teaching subjects remote to each student's core expertise. To address these challenges we adopt a number of approaches. We use three levels of instruments to foster integration across the disciplines: joint groups (e.g. a joint study programme), joint science questions (e.g. developed in annual symposia), and joint study sites. To maintain depth we apply a system of quality control including regular feedback sessions, theses by journal publications and international study exchange. For simultaneously teaching students from civil and environmental engineering, biology, geology, chemistry, mathematics we use visually explicit teaching, learning by doing, extra mentoring and by cross relating associated subjects. Our initial assessment of the Programme shows some very positive outcomes. Joint science questions formed between students from various disciplines indicate integration is being achieved. The number of successful publications in top journals suggests that depth is maintained. Positive feedback from the students on the variety and clarity of the courses indicates the teaching strategy is working well. Our experiences have shown that implementing and running an interdisciplinary doctoral programme has its challenges and is demanding in terms of time and human resources but seeing interactions progress and watching people grow and develop their way of thinking in an interdisciplinary environment is a valuable reward.

  11. Promoting interdisciplinary education - the Vienna Doctoral Programme on Water Resource Systems

    NASA Astrophysics Data System (ADS)

    Blöschl, G.; Carr, G.; Bucher, C.; Farnleitner, A. H.; Rechberger, H.; Wagner, W.; Zessner, M.

    2011-11-01

    The Vienna Doctoral Programme on Water Resource Systems (DK-WRS) is a programme that aims to educate students in interdisciplinary water science through cutting edge research at an international level. It is funded by the Austrian Science Fund and designed to run over a period of 12 yr during which 80 doctoral students are anticipated to graduate. This paper reports on our experiences of setting up and implementing the Programme. We identify three challenges: integrating the disciplines, maintaining depth in an interdisciplinary programme, and teaching subjects remote to each student's core expertise. To address these challenges we adopted a number of approaches. We use three levels of instruments to foster integration across the disciplines: joint groups (e.g. a joint study programme), joint science questions (e.g. developed in annual symposia), and joint study sites. To maintain depth we apply a system of quality control including regular feedback sessions, theses by journal publications and international study exchange. For simultaneously teaching students from civil and environmental engineering, biology, geology, chemistry, mathematics we use visually explicit teaching, learning by doing, extra mentoring and by cross relating associated subjects. Our initial assessment of the Programme shows some very positive outcomes. Joint science questions formed between students from various disciplines indicate integration is being achieved. The number of successful publications in top journals suggests that depth is maintained. Positive feedback from the students on the variety and clarity of the courses indicates the teaching strategy is working well. Our experiences have shown that implementing and running an interdisciplinary doctoral programme has its challenges and is demanding in terms of time and human resources but seeing interactions progress and watching people grow and develop their way of thinking in an interdisciplinary environment is a valuable reward.

  12. General purpose programmable accelerator board

    DOEpatents

    Robertson, Perry J. (Albuquerque, NM); Witzke, Edward L. (Edgewood, NM)

    2001-01-01

    A general purpose accelerator board and acceleration method comprising use of: one or more programmable logic devices; a plurality of memory blocks; bus interface for communicating data between the memory blocks and devices external to the board; and dynamic programming capabilities for providing logic to the programmable logic device to be executed on data in the memory blocks.

  13. Altera Corporation 1 Programmable Logic

    E-print Network

    Wawrzynek, John

    ® Altera Corporation 1 Mercury Programmable Logic Device Family January 2003, ver. 2.2 Data Sheet DS-MERCURY-2.2 13 Tools Features... High-performance programmable logic device (PLD) family (see. Mercury Device Features Feature EP1M120 EP1M350 Typical gates 120,000 350,000 HSDI channels 8 18 LEs 4

  14. In this issue... Current programmes

    E-print Network

    1 In this issue... Current programmes· Women in Mathematics· Day 2013 Donation for INI· Group visits to the Institute· Upcoming events· Transatlantic interview· with Jerry Ericksen Newsletter Isaac with the Mathematics of Liquid Crystals programme between 26 June and 6 July. The event provides interdisciplinary

  15. Japan's Eco-School Programme

    ERIC Educational Resources Information Center

    Mori, Masayuki

    2007-01-01

    Since 1997, several ministries in Japan have collaborated on an eco-school programme, which applies to both newly constructed and renovated school buildings, in an effort to make its schools more environmentally friendly. The programme equips school buildings with ecological features such as photovoltaic cells, solar thermal collectors, other new…

  16. Programmation Structure Master1 BBSG

    E-print Network

    Tichit, Laurent

    faire un clone de l'un des programmes de la suite EMBOSS : restrict « Finds restriction enzyme cleavage des enzymes de restrictions (base de données REBASE) Pour ce programme il n'y a que 2 choses à faire enzymes de restriction Le point d'entrée de REBASE est : http://rebase.neb.com/rebase/rebase.html. Il faut

  17. GCS programmer's manual

    NASA Technical Reports Server (NTRS)

    Lowman, Douglas S.; Withers, B. Edward; Shagnea, Anita M.; Dent, Leslie A.; Hayhurst, Kelly J.

    1990-01-01

    A variety of instructions to be used in the development of implementations of software for the Guidance and Control Software (GCS) project is described. This document fulfills the Radio Technical Commission for Aeronautics RTCA/DO-178A guidelines, 'Software Considerations in Airborne Systems and Equipment Certification' requirements for document No. 4, which specifies the information necessary for understanding and programming the host computer, and document No. 12, which specifies the software design and implementation standards that are applicable to the software development and testing process. Information on the following subjects is contained: activity recording, communication protocol, coding standards, change management, error handling, design standards, problem reporting, module testing logs, documentation formats, accuracy requirements, and programmer responsibilities.

  18. Programmable Cadence Timer

    NASA Technical Reports Server (NTRS)

    Hall, William A.; Gilbert, John

    1990-01-01

    Electronic metronome paces users through wide range of exercise routines. Conceptual programmable cadence timer provides rhythmic aural and visual cues. Timer automatically changes cadence according to program entered by the user. It also functions as clock, stopwatch, or alarm. Modular pacer operated as single unit or as two units. With audiovisual module moved away from base module, user concentrates on exercise cues without distraction from information appearing on the liquid-crystal display. Variety of uses in rehabilitative medicine, experimental medicine, sports, and gymnastics. Used in intermittent positive-pressure breathing treatment, in which patient must rhythmically inhale and retain medication delivered under positive pressure; and in incentive spirometer treatment, in which patient must inhale maximally at regular intervals.

  19. Approximate programmable quantum processors

    SciTech Connect

    Hillery, Mark; Ziman, Mario; Buzek, Vladimir

    2006-02-15

    A quantum processor is a programmable quantum circuit in which both the data and the program, which specifies the operation that is carried out on the data, are quantum states. We study the situation in which we want to use such a processor to approximate a set of unitary operators to a specified level of precision. We measure how well an operation is performed by the process fidelity between the desired operation and the operation produced by the processor. We show how to find the program for a given processor that produces the best approximation of a particular unitary operation. We also place bounds on the dimension of the program space that is necessary to approximate a set of unitary operators to a specified level of precision.

  20. Fast Flux Watch: A mechanism for online detection of fast flux networks.

    PubMed

    Al-Duwairi, Basheer N; Al-Hammouri, Ahmad T

    2014-07-01

    Fast flux networks represent a special type of botnets that are used to provide highly available web services to a backend server, which usually hosts malicious content. Detection of fast flux networks continues to be a challenging issue because of the similar behavior between these networks and other legitimate infrastructures, such as CDNs and server farms. This paper proposes Fast Flux Watch (FF-Watch), a mechanism for online detection of fast flux agents. FF-Watch is envisioned to exist as a software agent at leaf routers that connect stub networks to the Internet. The core mechanism of FF-Watch is based on the inherent feature of fast flux networks: flux agents within stub networks take the role of relaying client requests to point-of-sale websites of spam campaigns. The main idea of FF-Watch is to correlate incoming TCP connection requests to flux agents within a stub network with outgoing TCP connection requests from the same agents to the point-of-sale website. Theoretical and traffic trace driven analysis shows that the proposed mechanism can be utilized to efficiently detect fast flux agents within a stub network. PMID:25685515

  1. Fast Flux Watch: A mechanism for online detection of fast flux networks

    PubMed Central

    Al-Duwairi, Basheer N.; Al-Hammouri, Ahmad T.

    2014-01-01

    Fast flux networks represent a special type of botnets that are used to provide highly available web services to a backend server, which usually hosts malicious content. Detection of fast flux networks continues to be a challenging issue because of the similar behavior between these networks and other legitimate infrastructures, such as CDNs and server farms. This paper proposes Fast Flux Watch (FF-Watch), a mechanism for online detection of fast flux agents. FF-Watch is envisioned to exist as a software agent at leaf routers that connect stub networks to the Internet. The core mechanism of FF-Watch is based on the inherent feature of fast flux networks: flux agents within stub networks take the role of relaying client requests to point-of-sale websites of spam campaigns. The main idea of FF-Watch is to correlate incoming TCP connection requests to flux agents within a stub network with outgoing TCP connection requests from the same agents to the point-of-sale website. Theoretical and traffic trace driven analysis shows that the proposed mechanism can be utilized to efficiently detect fast flux agents within a stub network. PMID:25685515

  2. New indicators for global crop monitoring in CropWatch -case study in North China Plain

    NASA Astrophysics Data System (ADS)

    Bingfang, Wu; Miao, Zhang; Hongwei, Zeng; Guoshui, Liu; Sheng, Chang; Gommes, René

    2014-03-01

    CropWatch is a monitoring system developed and operated by the Institute of Remote Sensing and Digital Earth (Chinese Academy of Sciences) to provide global-scale crop information. Now in its 15th year of operation, CropWatch was modified several times to be a timely, comprehensive and independent global agricultural monitoring system using advanced remote sensing technology. Currently CropWatch is being upgraded with new indicators based on new sensors, especially those on board of China Environmental Satellite (HJ-1 CCD), the Medium Resolution Spectral Imager (MERSI) on Chinese meteorological satellite (FY-3A) and cloud classification products of FY-2. With new satellite data, CropWatch will generate new indicators such as fallow land ratio (FLR), crop condition for irrigated (CCI) and non-irrigated (CCNI) areas separately, photosynthetically active radiation (PAR), radiation use efficiency for the photosynthetically active radiation (RUEPAR) and cropping index (CI) with crop rotation information (CRI). In this paper, the methods for monitoring the new indicators are applied to the North China Plain which is one of the major grain producing areas in China. This paper shows the preliminary results of the new indicators and methods; they still need to be thoroughly validated before being incorporated into the operational CropWatch system. In the future, the new and improved indicators will help us to better understand the global situation of food security.

  3. The UPANAYAN' early intervention programme.

    PubMed

    Krishnaswamy, J

    1992-01-01

    The Upanayan programme is a product of Indchem Research and Development Laboratory, a scientific association recognized by Government of India, Ministry of Science and Technology. The objective of the project was to develop a computer assisted programme for the training of persons with mental retardation. The project was executed by an inter disciplinary team of experts. The focus of the training programme is the mother who is the intervening agent. The programme, developed in the first phase of the project, is an expert system for the infant stimulation and early intervention process for children below 2 years of age with the disability. The system comprises of: (i) a development check list of skills for assessment and programming, (ii) a profile to record the observations, (iii) intervention strategies in the form of activities to acquire all the skills in the check list. The programme is designed for the Indian socio-economic conditions and is available in the form of a printed manual, and also as a computer software. The two can be used independently of each other. The programme has been translated into Hindi, Tamil, Malayalam and Marathi. With this programme as the basis, a centre for early intervention, Madhuram Narayanan Centre for Exceptional Children--was set up in Madras about 3 years back. Presently 210 children are receiving training there. The Centre has evolved intervention strategies based on parental involvement, with salutary effect on the parents as well as on the children. PMID:1340858

  4. Automatic TLI recognition system, programmer`s guide

    SciTech Connect

    Lassahn, G.D.

    1997-02-01

    This report describes the software of an automatic target recognition system (version 14), from a programmer`s point of view. The intent is to provide information that will help people who wish to modify the software. In separate volumes are a general description of the ATR system, Automatic TLI Recognition System, General Description, and a user`s manual, Automatic TLI Recognition System, User`s Guide. 2 refs.

  5. Television and families: what do young children watch with their parents?

    PubMed

    St Peters, M; Fitch, M; Huston, A C; Wright, J C; Eakins, D J

    1991-12-01

    A sample of 271 3- and 5-year-olds and their families participated in a 2-year longitudinal study of television viewing patterns. 5 1-week diaries for all family members were collected at 6-month intervals. Programs were categorized as: (1) child informative, (2) child entertainment, (3) news and informative, (4) sports, (5) comedy, (6) drama, (7) action-adventure, and (8) variety-game. The majority of child programs were viewed without parents, while the majority of adult programs were watched with parents. Coviewing patterns of adult programs were predicted from parents' individual viewing habits, but not from the child's. Coviewing declined with age. Parental encouragement and regulation of viewing were orthogonal. Children whose parents encouraged viewing watched more child informative programming; children of restrictive parents watched less entertainment programming. Encouraging parents coviewed more than nonencouraging parents. Results support the assertion that parental viewing preferences, habits, and orientations toward television influence children's viewing, both with and without parents. PMID:1786724

  6. Programmable electronic synthesized capacitance

    NASA Technical Reports Server (NTRS)

    Kleinberg, Leonard L. (inventor)

    1987-01-01

    A predetermined and variable synthesized capacitance which may be incorporated into the resonant portion of an electronic oscillator for the purpose of tuning the oscillator comprises a programmable operational amplifier circuit. The operational amplifier circuit has its output connected to its inverting input, in a follower configuration, by a network which is low impedance at the operational frequency of the circuit. The output of the operational amplifier is also connected to the noninverting input by a capacitor. The noninverting input appears as a synthesized capacitance which may be varied with a variation in gain-bandwidth product of the operational amplifier circuit. The gain-bandwidth product may, in turn, be varied with a variation in input set current with a digital to analog converter whose output is varied with a command word. The output impedance of the circuit may also be varied by the output set current. This circuit may provide very small ranges in oscillator frequency with relatively large control voltages unaffected by noise.

  7. Scientific Programme Committee

    NASA Astrophysics Data System (ADS)

    2013-02-01

    Scientific Programme Committee A. Blondel, University of Geneva A. Cervera, IFIC M. Dracos, IN2P3 I. Efhymiopoulos, CERN J. Ellis, CERN S. Geer, FNAL R. Garoby, CERN M. Goodman, ANL D. Harris, FNAL T. Hasegawa, KEK P. Huber, Virginia Tech. D. Kaplan, IIT Y.D. Kim, Sejong University H. Kirk, BNL Y. Kuno, Osaka University K. Long, Imperial College N.K. Mondal, TIFR J. Morfin, FNAL Y. Mori, Kyoto University K. Nishikawa, KEK V. Palladino, University of Napoli C. Prior, RAL F.J.P. Soler, University of Glasgow J. Strait, FNAL R. Svoboda, University of California Davis F. Terranova, LN Frascati M. Zisman, LBNL Local Organizing Committee E. Benedetto, CERN/NTUA C. Blanchard, University of Geneva A. Blondel, University of Geneva (co-chair) I. Efthymiopoulos, CERN (co-chair) F. Dufour, University of Geneva F. Girard-Madoux, CERN E. Gschwendtner, CERN A. Korzenev, University of Geneva M. Morer-Olafsen, CERN S. Murphy, University of Geneva G. Prior, CERN G. Wikström, University of Geneva E. Wildner, CERN Sponsors EuCARD European Organization for Nuclear Research (CERN) Swiss Institute for Particle Physics (CHIPP) University of Geneva

  8. ALICE pp physics programme

    E-print Network

    Ingrid Kraus; for the ALICE Collaboration

    2009-07-09

    The physics programme of the ALICE experiment at CERN-LHC comprises besides studies of high-energy heavy-ion collisions measurements of proton-proton interactions at unprecedented energies, too. This paper focuses on the global event characterisation in terms of the multiplicity distribution of charged hadrons and mean transverse momentum. These bulk observables become accessible because the detector features excellent track reconstruction, especially at low transverse momenta. The measurement of strange hadrons is of particular interest since the strange-particle phase-space was found to be suppressed beyond canonical reduction at lower center-of-mass energies and the production mechanism of soft particles is not yet fully understood. Here we benefit in particular from particle identification down to very low transverse momentum, i.e. 100 - 300 MeV/c, giving access to spectra and integrated yields of identified hadrons. Equipped with these features, ALICE will play a complementary role w.r.t. other LHC experiments. New interest in the soft part of pp collisions arose recently and new insights in the physics of the underlying event are expected from both, theory and experiment.

  9. Physical activity and television watching in relation to semen quality in young men

    PubMed Central

    Gaskins, Audrey J; Mendiola, Jaime; Afeiche, Myriam; Jørgensen, Niels; Swan, Shanna H; Chavarro, Jorge E

    2013-01-01

    Background Semen quality appears to have declined over the past decades but reasons for this decline are unresolved. The concurrent increase in sedentary behavior may be a contributing factor. The objective of this study was to evaluate the relationship of physical activity and television (TV) watching with sperm parameters in a population of young, healthy men Methods Men aged 18-22 years (n=189) from the Rochester Young Men's Study (2009-2010) were used in this analysis. Physical activity (hours/week of moderate and vigorous exercise) and TV watching (hours/week of TV, video, or DVD watching) over the past 3 months was assessed via questionnaire. Semen quality was assessed by sperm concentration, motility, morphology, and total sperm count. Results Sperm concentration and total sperm count were directly related to physical activity after multivariable adjustment (p-trend=0.01 and 0.04); men in the highest quartile of moderate-to-vigorous activity (?15 hours/week) had 73% (95% CI 15 to 160%) higher sperm concentration than men in the lowest quartile (< 5 hours/week). TV watching was inversely associated with sperm concentration and total sperm count in multivariable analyses (p-trend=0.05 and 0.06); men in the highest quartile of TV watching (>20 hours/week) had 44% (95% CI 15 to 63%) lower sperm concentration than men in the lowest quartile (0 hours/week). These measures of physical and leisure time activities were not significantly associated with sperm motility or morphology. Conclusions In this population of healthy men, higher moderate-to-vigorous activity and less TV watching were significantly associated with higher total sperm count and sperm concentration. PMID:23380634

  10. Electrical classification for the single shell flammable gas watch list tanks

    SciTech Connect

    Huckfeldt, R.A.; Anderson, R.A.

    1995-04-01

    This document is to establish the hazard classification of single shell watch list tanks according to National Fire Protection Association (NFPA) criteria and sound engineering judgment. Establishing the hazard classification is necessary to determine the appropriate wiring methods and installation of electrical and mechanical equipment assure safety in an atmosphere that may be hazardous. The tanks have been placed on the flammable gas watch list because their waste types are similar to those in tanks that exhibit episodic behavior and/or unexplained growth of the waste-level height occuring over time. They contain mostly solid wastes.

  11. International Mussel Watch: A global assessment of environmental levels of chemical contaminants

    SciTech Connect

    Not Available

    1992-01-01

    The primary goal of the International Mussel Watch is to ascertain and assess the levels of chlorinated hydrocarbon pesticide (CHP) and polychlorinated biphenyls (PCB) in bivalves collected from coastal marine waters throughout the world. Increased use of these persistent toxic biocides may result in contamination of living coastal resources from whole ecosystems to specific food resources with consequent implication for human health and the integrity of marine communities. Another goal for the International Mussel Watch Project will be to help develop a sustainable activity for observation and monitoring chemical contamination in especially susceptible regions of the world's oceans.

  12. Identification of a homicide victim by a Casio data bank watch.

    PubMed

    Costello, J; Zugibe, F T

    1994-07-01

    A positive identification of a homicide victim was made possible by observing an inconspicuous Casio watch worn by the deceased. Identification of deceased individuals are usually made by fingerprints or dental matching, visual means, DNA studies, X-rays of other bodily structures, tattoos, etc. When all of these methods fail and no suspects are known, medical examiners are caught between Charybdis and Scilla. This assumes greater importance in cases of homicides. It is the purpose of this paper to present a homicide case in which an identification was made by observing an inconspicuous object, a small Casio watch worn by the deceased. PMID:8064272

  13. Electrically-programmable diffraction grating

    DOEpatents

    Ricco, A.J.; Butler, M.A.; Sinclair, M.B.; Senturia, S.D.

    1998-05-26

    An electrically-programmable diffraction grating is disclosed. The programmable grating includes a substrate having a plurality of electrodes formed thereon and a moveable grating element above each of the electrodes. The grating elements are electrostatically programmable to form a diffraction grating for diffracting an incident beam of light as it is reflected from the upper surfaces of the grating elements. The programmable diffraction grating, formed by a micromachining process, has applications for optical information processing (e.g. optical correlators and computers), for multiplexing and demultiplexing a plurality of light beams of different wavelengths (e.g. for optical fiber communications), and for forming spectrometers (e.g. correlation and scanning spectrometers). 14 figs.

  14. Field Evaluation of Programmable Thermostats

    SciTech Connect

    Sachs, O.; Tiefenbeck, V.; Duvier, C.; Qin, A.; Cheney, K.; Akers, C.; Roth, K.

    2012-12-01

    Prior research suggests that poor programmable thermostats usability may prevent their effective use to save energy. The Fraunhofer team hypothesized that home occupants with high-usability thermostats would be more likely to use them to save energy than people with a basic thermostats. In this report, the team discusses results of a project in which the team monitored and compared programmable thermostats with basic thermostats in an affordable housing apartment complex.

  15. FSC-Watch: FSC undermines paper recycling, contributes to global warming FSC undermines paper recycling, contributes to global

    E-print Network

    FSC-Watch: FSC undermines paper recycling, contributes to global warming FSC-Watch FSC undermines paper recycling, contributes to global warming Tags: Canada, Recycling, Certifier conflict of interest industry, as to why the FSC is helping to undermine efforts at paper recycling by allowing

  16. 78 FR 2683 - Carriage Standards for Bridge Navigational Watch Alarm Systems (BNWAS) Aboard U.S. Flagged Vessels

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... SECURITY Coast Guard Carriage Standards for Bridge Navigational Watch Alarm Systems (BNWAS) Aboard U.S... Guard announces the implementation date of carriage standards for Bridge Navigational Watch Alarm... bridge. Consistent with the position of other SOLAS member flag states, the Coast Guard does not...

  17. The role of intergenerational influence in waste education programmes: The THAW project

    SciTech Connect

    Maddox, P.; Doran, C.; Williams, I.D.; Kus, M.

    2011-12-15

    Highlights: > Children can be effective advocates in changing their parents' lifestyles. > We investigated the role of intergenerational influence in waste education programmes. > Waste Watch's Take Home Action on Waste project worked with 6705 children in 39 schools. > The results showed increased participation in recycling and declines in residual waste. > The study shows that recycling behaviour is positively impacted by intergenerational influence. - Abstract: Whilst the education of young people is often seen as a part of the solution to current environmental problems seeking urgent attention, it is often forgotten that their parents and other household members can also be educated/influenced via home-based educational activities. This paper explores the theory of intergenerational influence in relation to school based waste education. Waste Watch, a UK-based environmental charity ((www.wastewatch.org.uk)), has pioneered a model that uses practical activities and whole school involvement to promote school based action on waste. This methodology has been adopted nationally. This paper outlines and evaluates how effective school based waste education is in promoting action at a household level. The paper outlines Waste Watch's 'Taking Home Action on Waste (THAW)' project carried out for two and half years in Rotherham, a town in South Yorkshire, England. The project worked with 6705 primary age children in 39 schools (44% of primary schools in the project area) to enable them to take the 'reduce, reuse and recycle message' home to their families and to engage these (i.e. families) in sustainable waste management practices. As well as substantial increases in students' knowledge and understanding of waste reduction, measurement of the impact of the project in areas around 12 carefully chosen sample schools showed evidence of increased participation in recycling and recycling tonnages as well as declining levels of residual waste. Following delivery of the project in these areas, an average increase of 8.6% was recorded in recycling set out rates which led to a 4.3% increase in paper recycling tonnages and an 8.7% increase in tonnages of cans, glass and textiles collected for recycling. Correspondingly, there was a 4.5% fall in tonnages of residual waste. Waste Watch's THAW project was the first serious attempt to measure the intergenerational influence of an education programme on behaviour at home (i.e. other than schools' own waste). It clearly shows that household recycling behaviour can be positively impacted by intergenerational influence via a practical school-based waste education model. However, although the model could potentially have a big impact if rolled out nationally, it will require seed funding and the long-term durability of the model has not yet been fully quantified.

  18. Computer Science at Bath Degree programmes in

    E-print Network

    Vorobjov, Nicolai

    Computer Science at Bath Degree programmes in Computer Science Computer Science and Mathematics Computer Science with Business #12;Computer Science programmes Programme UCaS DUration CoDe of Programme BSc (Hons) Computer Science g400 3 years BSc (Hons) Computer Science with placement year g401 4 years

  19. BusView and Transit Watch: an Update on Two Products from the

    E-print Network

    1 BusView and Transit Watch: an Update on Two Products from the Seattle SMART TREK Model Deployment Trek model deployment, two new applications where created to provide real-time transit information. The two venues where transit riders need information are (1) on the desktop and (2) at the transit center

  20. 33 CFR 110.47 - Little Narragansett Bay, Watch Hill, R.I.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... All of the navigable waters of Watch Hill Cove southeasterly of a line beginning at the shore end of the United States project groin on the southerly shore of the cove and running 41°30? true, to the northerly shore of the cove at a point about 200...

  1. 33 CFR 110.47 - Little Narragansett Bay, Watch Hill, R.I.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... All of the navigable waters of Watch Hill Cove southeasterly of a line beginning at the shore end of the United States project groin on the southerly shore of the cove and running 41°30? true, to the northerly shore of the cove at a point about 200...

  2. 33 CFR 110.47 - Little Narragansett Bay, Watch Hill, R.I.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... All of the navigable waters of Watch Hill Cove southeasterly of a line beginning at the shore end of the United States project groin on the southerly shore of the cove and running 41°30? true, to the northerly shore of the cove at a point about 200...

  3. 33 CFR 110.47 - Little Narragansett Bay, Watch Hill, R.I.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... All of the navigable waters of Watch Hill Cove southeasterly of a line beginning at the shore end of the United States project groin on the southerly shore of the cove and running 41°30? true, to the northerly shore of the cove at a point about 200...

  4. 33 CFR 110.47 - Little Narragansett Bay, Watch Hill, R.I.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... All of the navigable waters of Watch Hill Cove southeasterly of a line beginning at the shore end of the United States project groin on the southerly shore of the cove and running 41°30? true, to the northerly shore of the cove at a point about 200...

  5. Community Solutions for Solid Waste Pollution, Level 6. Teacher Guide. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Waste Management, Richmond. Div. of Litter & Recycling.

    Operation Waste Watch is a series of seven sequential learning units which addresses the subject of litter control and solid waste management. Each unit may be used in a variety of ways, depending on the needs and schedules of individual schools, and may be incorporated into various social studies, science, language arts, health, mathematics, and…

  6. Folklore in Zora Neale Hurston's "Their Eyes Were Watching God." [Lesson Plan].

    ERIC Educational Resources Information Center

    2002

    Zora Neale Hurston's work is lively, lyrical, funny, and poignant, but this consummate literary craftsperson was also a first-rate ethnographer, conducting field work for Franz Boas and for the Works Progress Administration (WPA). "Their Eyes Were Watching God," often acclaimed as Hurston's masterpiece, is perhaps the richest beneficiary of her…

  7. 49 CFR 1560.107 - Use of watch list matching results by covered aircraft operators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Use of watch list matching results by covered aircraft operators. 1560.107 Section 1560.107 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY SECURE FLIGHT PROGRAM Collection...

  8. 49 CFR 1560.107 - Use of watch list matching results by covered aircraft operators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Use of watch list matching results by covered aircraft operators. 1560.107 Section 1560.107 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY SECURE FLIGHT PROGRAM Collection...

  9. Watch Global, Cache Local: YouTube Network Traffic at a Campus Network -Measurements and Implications

    E-print Network

    Massachusetts at Amherst, University of

    Watch Global, Cache Local: YouTube Network Traffic at a Campus Network - Measurements of web services such as YouTube allowing the distribution of such user-produced media content in an easy in YouTube is realized and then conduct a measurement study of YouTube traffic in a large university

  10. Watch, Discover, Think, and Act: A Model for Patient Education Program Development.

    ERIC Educational Resources Information Center

    Bartholomew, L. K.; Shegog, R.; Parcel, G. S.; Gold, R. S.; Fernandez, M.; Czyzewski, D. I.; Sockrider, M. M.; Berlin, N.

    2000-01-01

    Describes the development of the Watch, Discover, Think, and Act asthma self-management computer program for inner-city children with asthma. The intervention focuses on teaching two categories of behaviors: asthma specific behaviors such as taking preventive medication, and self-regulatory processes such as monitoring symptoms and solving asthma…

  11. Harmony: A Hand Wash Monitoring and Reminder System using Smart Watches

    E-print Network

    Stankovic, John A.

    , proper hand washing procedure comprises of different ways of rubbing the hands to ensure that no areaHarmony: A Hand Wash Monitoring and Reminder System using Smart Watches Md Abu Sayeed Mondol@cs.virginia.edu ABSTRACT Hand hygiene compliance is extremely important in hos- pitals, clinics and food businesses

  12. CLIMATE AND PERCEPTION The social impacts of the heathealth watch/warning system

    E-print Network

    Sheridan, Scott

    CLIMATE AND PERCEPTION The social impacts of the heat­health watch/warning system in Phoenix specifically, to gauge risk perception and warning response. Consistent with previous research, increased risk perception of heat results in increased response to a warning. Different social factors such as sex, race

  13. Validity of the Smarthealth Watch to Measure Heart Rate during Rest and Exercise

    ERIC Educational Resources Information Center

    Lee, C. Matthew; Gorelick, Mark

    2011-01-01

    The purpose of this study was to examine the validity of the Smarthealth watch (Salutron, Inc., Fremont, California, USA), a heart rate monitor that includes a wristwatch without an accompanying chest strap. Twenty-five individuals participated in 3-min periods of standing, 2.0 mph walking, 3.5 mph walking, 4.5 mph jogging, and 6.0 mph running.…

  14. 75 FR 67387 - Credit Watch Termination Initiative Termination of Origination Approval Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ...This notice advises of the cause and effect of termination of Origination Approval Agreements taken by HUD's Federal Housing Administration (FHA) against HUD-approved mortgagees through the FHA Credit Watch Termination Initiative. This notice includes a list of mortgagees which have had their Origination Approval Agreements...

  15. 75 FR 67388 - Credit Watch Termination Initiative; Termination of Direct Endorsement (DE) Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ...This notice advises of the cause and effect of termination of Direct Endorsement (DE) Approval taken by HUD's Federal Housing Administration (FHA) against HUD-approved mortgagees through the FHA Credit Watch Termination Initiative. This notice includes a list of mortgagees which have had their DE Approval...

  16. Originally published in EarthWatch. October-November 2002 The Termites' Dilemma

    E-print Network

    Turner, Scott

    Originally published in EarthWatch. October-November 2002 The Termites' Dilemma Scott Turner A termite queen surrounded by her sterile retinue I had an epiphany a few years ago: I realized that there was no such thing as a termite. My epiphany came while trying to decide whether organisms, like termites, or mice

  17. Improving Video Classification via YouTube Video Co-Watch Data

    E-print Network

    Cortes, Corinna

    Improving Video Classification via YouTube Video Co-Watch Data John R. Zhang Dept. Computer View, USA leungt@google.com ABSTRACT Classification of web-based videos is an important task with many applications in video search and ads targeting. How- ever, collecting labeled data needed for classifier

  18. 77 FR 5263 - Credit Watch Termination Initiative Termination of Origination Approval Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... published a notice (64 FR 26769), on its procedures for terminating Origination Approval Agreements with FHA... URBAN DEVELOPMENT Credit Watch Termination Initiative Termination of Origination Approval Agreements..., Office of Housing, Department of Housing and Urban Development, 451 Seventh Street SW., Room...

  19. 77 FR 5262 - Credit Watch Termination Initiative Termination of Direct Endorsement (DE) Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... (64 FR 26769), on its procedures for terminating Origination Approval Agreements with FHA lenders and... URBAN DEVELOPMENT Credit Watch Termination Initiative Termination of Direct Endorsement (DE) Approval..., Department of Housing and Urban Development, 451 Seventh Street SW., Room B133-P3214, Washington, DC...

  20. N E U RO S C I E N C E Watchful Waking

    E-print Network

    Wilf, Peter

    ) and REM or dreaming sleep (which exhibits the strong 7 to 8 hertz theta activity associated with active1603 N E U RO S C I E N C E Watchful Waking Sleep is traditionally thought to consist of two states: slow- wave sleep (SWS) alternates with periods of rapid eye move- ment (REM) sleep.These two states can

  1. "Princess Alice Is Watching You": Children's Belief in an Invisible Person Inhibits Cheating

    ERIC Educational Resources Information Center

    Piazza, Jared; Bering, Jesse M.; Ingram, Gordon

    2011-01-01

    Two child groups (5-6 and 8-9 years of age) participated in a challenging rule-following task while they were (a) told that they were in the presence of a watchful invisible person ("Princess Alice"), (b) observed by a real adult, or (c) unsupervised. Children were covertly videotaped performing the task in the experimenter's absence. Older…

  2. 47 CFR 80.305 - Watch requirements of the Communications Act and the Safety Convention.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Watch requirements of the Communications Act and the Safety Convention...part II of title III of the Communications Act or chapter IV of the...part II of title III of the Communications Act or chapter IV of the...the vessel is beyond VHF communication range of the...

  3. STS-37 crewmembers watch Pilot Cameron juggle cassettes on OV-104's middeck

    NASA Technical Reports Server (NTRS)

    1991-01-01

    STS-37 crewmembers watch Pilot Kenneth D. Cameron juggle cassette tapes on the middeck of Atlantis, Orbiter Vehicle (OV) 104. Laughing at Cameron's stunt are Mission Specialist (MS) Linda M. Godwin (foreground), Commander Steven R. Nagel (behind Cameron), and MS Jerry L. Ross (at floor level). Ross snacks on chocolate candy during the performance.

  4. BirdWatch--Supporting Citizen Scientists for Better Linked Data Quality for Biodiversity

    E-print Network

    Hyvönen, Eero

    BirdWatch--Supporting Citizen Scientists for Better Linked Data Quality for Biodiversity Management biodiversity. The education and skills of the citizens participating in the work varies a lot, and the process of the observational data in repos- itories, such as the Global Biodiversity Information Facility GBIF Data Portal

  5. Apple watch: has its time come? Charles Arthur for guardian.co.uk

    E-print Network

    South Bohemia, University of

    Apple watch: has its time come? Charles Arthur for guardian.co.uk Apple's next big thing next year as consumers, fitness fanatics, healthcare and the military begin to adopt it. But if Apple to show data updates. But few people bought them, and Microsoft stopped selling it in 2008

  6. Even more exciting than the Apple Watch: ResearchKit | accrualnet.cancer.gov

    Cancer.gov

    Embedded in the splashy debut of the Apple Watch, was something that the clinical trials world will find pretty interesting. Apple introduced a new open source tool called ResearchKit. Along with academic partners, Apple developed and launched 5 clinical trial apps built with the ResearchKit tool.

  7. Television and Families: What Do Young Children Watch With Their Parents?

    ERIC Educational Resources Information Center

    St. Peters, Michelle; And Others

    This study investigated several questions concerning the amount of viewing and types of programs children and parents watch alone and together. Patterns of children's viewing with and without parents were examined, as well as how parent-child coviewing affects individual family members' viewing. Children 3 to 5 and 5 to 7 years old, and their…

  8. Watching energy transfer in metalloporphyrin heterodimers using stimulated X-ray

    E-print Network

    Mukamel, Shaul

    Watching energy transfer in metalloporphyrin heterodimers using stimulated X-ray Raman spectroscopy molecular electronics applications. Simulations of the stimulated X-ray Raman spectroscopy signals of a Zn/Ni porphyrin heterodimer induced by attosecond X-ray pulses show that these signals can directly reveal

  9. The Use of Common Planning Time: A Case Study of Two Kentucky Schools to Watch

    ERIC Educational Resources Information Center

    Cook, Christopher M.; Faulkner, Shawn A.

    2010-01-01

    Interdisciplinary teams with common planning time have been a hallmark of the middle school organizational structure since the 1960s, yet research on the effective use of common planning time is limited. This study explores how interdisciplinary teams at schools designated Kentucky Schools to Watch use common planning time, including the factors…

  10. Watching eyes on potential litter can reduce littering: evidence from two field experiments.

    PubMed

    Bateson, Melissa; Robinson, Rebecca; Abayomi-Cole, Tim; Greenlees, Josh; O'Connor, Abby; Nettle, Daniel

    2015-01-01

    Littering constitutes a major societal problem, and any simple intervention that reduces its prevalence would be widely beneficial. In previous research, we have found that displaying images of watching eyes in the environment makes people less likely to litter. Here, we investigate whether the watching eyes images can be transferred onto the potential items of litter themselves. In two field experiments on a university campus, we created an opportunity to litter by attaching leaflets that either did or did not feature an image of watching eyes to parked bicycles. In both experiments, the watching eyes leaflets were substantially less likely to be littered than control leaflets (odds ratios 0.22-0.32). We also found that people were less likely to litter when there other people in the immediate vicinity than when there were not (odds ratios 0.04-0.25) and, in one experiment but not the other, that eye leaflets only reduced littering when there no other people in the immediate vicinity. We suggest that designing cues of observation into packaging could be a simple but fruitful strategy for reducing littering. PMID:26644979

  11. Effects of watching eyes and norm cues on charitable giving in a surreptitious behavioral experiment.

    PubMed

    Fathi, Moe; Bateson, Melissa; Nettle, Daniel

    2014-01-01

    A series of experimental studies by multiple groups of researchers have found that displaying images of watching eyes causes people to behave more prosocially. It is not yet clear whether watching eyes increase prosocial motivation per se, or whether they simply make people's behavior more normative. Here, we report results from a surreptitious behavioral experiment examining the impacts of watching eye images and cues to local norms on charitable donations in a controlled setting. Eye images significantly increased average donations. Eye images did not make people conform more closely to the apparent norm overall. Instead, there were different patterns according to the apparent norm. For an apparent norm of small donations, eye images made many participants more generous than the norm. For an apparent norm of large donations, there was an excess of participants giving zero in the no-eyes treatment, which was abolished in the eyes treatment. Our results can be explained by a combination of watching eyes increasing prosocial motivation and reluctance to leave a donation visibly less generous than the norm. PMID:25331033

  12. Does Watching Television Rot Your Mind? Estimates of the Effect on Test Scores

    ERIC Educational Resources Information Center

    Zavodny, Madeline

    2006-01-01

    This study examines whether the number of hours of television watched by young adults is associated with performance on standardized exams and whether any such relationship is causal. Data from the National Longitudinal Survey of Youth, the High School and Beyond survey and the National Education Longitudinal Study all indicate a negative…

  13. Watching an Enzyme at Work: A Mass Spectrometry View of Allosteric Citrate Synthase

    E-print Network

    Ens, Werner

    Watching an Enzyme at Work: A Mass Spectrometry View of Allosteric Citrate Synthase Lynda J. Donald Citrate synthase is the enzyme at the entry point of the citric acid cycle. In Gram-negative bacteria of the wild-type enzyme from Escherichia coli shows three quasi- symmetrical dimers arranged around a 3-fold

  14. Natural and Man-Made Objects, Level K. Teacher's Guide. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Waste Management, Richmond. Div. of Litter & Recycling.

    Operation Waste Watch is a series of seven sequential learning units which addresses the subject of litter control and solid waste management. Each unit may be used in a variety of ways, depending on the needs and schedules of individual schools, and may be incorporated into various social studies, science, language arts, health, mathematics, and…

  15. Waste Out of Place, Level 1. Teacher Guide. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Waste Management, Richmond. Div. of Litter & Recycling.

    Operation Waste Watch is a series of seven sequential learning units which addresses the subject of litter control and solid waste management. Each unit may be used in a variety of ways, depending on the needs and schedules of individual schools, and may be incorporated into various social studies, science, language arts, health, mathematics, and…

  16. Let's Waste Less Waste, Level 4. Teacher Guide. Operation Waste Watch.

    ERIC Educational Resources Information Center

    Virginia State Dept. of Waste Management, Richmond. Div. of Litter & Recycling.

    Operation Waste Watch is a series of seven sequential learning units which addresses the subject of litter control and solid waste management. Each unit may be used in a variety of ways, depending on the needs and schedules of individual schools, and may be incorporated into various social studies, science, language arts, health, mathematics, and…

  17. 33 CFR 157.420 - Vessel specific watch policy and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Vessel specific watch policy and procedures. 157.420 Section 157.420 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim...

  18. 33 CFR 157.420 - Vessel specific watch policy and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Vessel specific watch policy and procedures. 157.420 Section 157.420 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim...

  19. WATCH: WiFi in Active TV Channels Xu Zhang and Edward W. Knightly

    E-print Network

    Natelson, Douglas

    WATCH: WiFi in Active TV Channels Xu Zhang and Edward W. Knightly Rice University, Houston, Texas in the UHF TV band allows channels that are not being used regionally by a TV broadcaster to be re channels for white space usage. Nonetheless, from the UHF TV view- er's perspective, Nielsen data show

  20. NATURE METHODS | VOL.5 NO.1 | JANUARY 2008 | 25 METHODS TO WATCH | SPECIAL FEATURE

    E-print Network

    Cai, Long

    NATURE METHODS | VOL.5 NO.1 | JANUARY 2008 | 25 METHODS TO WATCH | SPECIAL FEATURE The challenge the extent of information a true`meta-database' couldprovide;a scientist starts a search with, for example accessible meta-network so people can optimally use knowledge generated outside their own box of expertise

  1. Volunteer Watershed Health Monitoring by Local Stakeholders: New Mexico Watershed Watch

    ERIC Educational Resources Information Center

    Fleming, William

    2003-01-01

    Volunteers monitor watershed health in more than 700 programs in the US, involving over 400,000 local stakeholders. New Mexico Watershed Watch is a student-based watershed monitoring program sponsored by the state's Department of Game and Fish which provides high school teachers and students with instruction on methods for water quality…

  2. Watching eyes on potential litter can reduce littering: evidence from two field experiments

    PubMed Central

    Bateson, Melissa; Robinson, Rebecca; Abayomi-Cole, Tim; Greenlees, Josh; O’Connor, Abby

    2015-01-01

    Littering constitutes a major societal problem, and any simple intervention that reduces its prevalence would be widely beneficial. In previous research, we have found that displaying images of watching eyes in the environment makes people less likely to litter. Here, we investigate whether the watching eyes images can be transferred onto the potential items of litter themselves. In two field experiments on a university campus, we created an opportunity to litter by attaching leaflets that either did or did not feature an image of watching eyes to parked bicycles. In both experiments, the watching eyes leaflets were substantially less likely to be littered than control leaflets (odds ratios 0.22–0.32). We also found that people were less likely to litter when there other people in the immediate vicinity than when there were not (odds ratios 0.04–0.25) and, in one experiment but not the other, that eye leaflets only reduced littering when there no other people in the immediate vicinity. We suggest that designing cues of observation into packaging could be a simple but fruitful strategy for reducing littering. PMID:26644979

  3. Crewmen of the U.S.S. Wasp watching recovery of Gemini 6 spacecraft

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Crewmen of the aircraft carrier U.S.S. Wasp gather on deck to watch the recovery of the Gemini 6 spacecraft and astronauts. Note the signs hanging from the railings which say 'Seasons Greetings from WASP' and 'Spirit of 76'.

  4. Crewmen of the U.S.S. Wasp watching recovery of Gemini 7 spacecraft

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Crewmen of the aircraft carrier U.S.S. Wasp gather on deck to watch the recovery of the Gemini 7 spacecraft and astronauts. Note the signs hanging from the railings which say 'Seasons Greetings from WASP' and 'Spirit of 76'.

  5. 76 FR 4364 - Credit Watch Termination Initiative; Termination of Direct Endorsement (DE) Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... published a notice (64 FR 26769), on its procedures for terminating Origination Approval Agreements with FHA... URBAN DEVELOPMENT Credit Watch Termination Initiative; Termination of Direct Endorsement (DE) Approval..., Department of Housing and Urban Development, 451 Seventh Street, SW., Room B133-P3214, Washington, DC...

  6. Environmental Monitoring of Lake Michigan Using CoastWatch Data and JAVA GIS

    E-print Network

    Environmental Monitoring of Lake Michigan Using CoastWatch Data and JAVA GIS George A. Leshkevich Observation Data) Statistics (Great Lakes Average Surface Water Temperature) JAVA GIS (JAVA Applet) CDAT activities. New utilities such as JAVA based interactive retrieval of physical parameters such as surface

  7. Analysis of NWS/SPC Watch Counts by Partial Winter and Spring Astronomical Seasons (January 1 to March 19 & March 20 to June 6)

    E-print Network

    Analysis of NWS/SPC Watch Counts by Partial Winter and Spring Astronomical Seasons (January 1 to March 19 & March 20 to June 6) Greg Carbin NOAA/NWS/Storm Prediction Center Winter Season* Watch Summary (*defined here as the "winter season"), in reverse annual order. Percent of normal watch count values

  8. Programmable data communications controller requirements

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The design requirements for a Programmable Data Communications Controller (PDCC) that reduces the difficulties in attaching data terminal equipment to a computer are presented. The PDCC is an interface between the computer I/O channel and the bit serial communication lines. Each communication line is supported by a communication port that handles all line control functions and performs most terminal control functions. The port is fabricated on a printed circuit board that plugs into a card chassis, mating with a connector that is joined to all other card stations by a data bus. Ports are individually programmable; each includes a microprocessor, a programmable read-only memory for instruction storage, and a random access memory for data storage.

  9. Multiple channel programmable coincidence counter

    DOEpatents

    Arnone, Gaetano J. (Los Alamos, NM)

    1990-01-01

    A programmable digital coincidence counter having multiple channels and featuring minimal dead time. Neutron detectors supply electrical pulses to a synchronizing circuit which in turn inputs derandomized pulses to an adding circuit. A random access memory circuit connected as a programmable length shift register receives and shifts the sum of the pulses, and outputs to a serializer. A counter is input by the adding circuit and downcounted by the seralizer, one pulse at a time. The decoded contents of the counter after each decrement is output to scalers.

  10. Computer, Programme Programmiersprachen, Compiler Erste Java-Programme Objektorientierte Programmierung

    E-print Network

    Brass, Stefan

    Programmierung Kapitel 1: Einf¨uhrung Stefan Brass Martin-Luther-Universit¨at Halle-Wittenberg Wintersemester 2013/14 http://www.informatik.uni-halle.de/~brass/oop13/ Stefan Brass: OOP (Java), 1. Einf¨uhrung 1, Umgang mit Syntaxfehlern Stefan Brass: OOP (Java), 1. Einf¨uhrung 2/67 #12;Computer, Programme

  11. Vagotonicity of Violence: Biochemical and Cardiac Responses to Violent Films and Television Programmes

    PubMed Central

    Carruthers, Malcolm; Taggart, Peter

    1973-01-01

    In a search for a reproducible means of evoking different types of emotional stress it was found that in spite of increased adrenaline secretion slowing of the heart occurred when watching violent television programmes. Further evidence of increased vagal tone was provided by the “sinus arrhythmia” effect, a widening of the gap between the maximum and minimum heart rates during the respiratory cycle in parts of the humour, violence, and suspense sections of the television programme. Groups of people taken to see two particularly violent films showed similar evidence suggesting vagal overactivity, together with increases in plasma free fatty acids and decreases in triglycerides. As these changes occurred even with ?-blockade it is suggested that they might be caused by non-sympathetically mediated changes in the levels of hormones, such as growth hormone, producing lipolysis. The ability to assess objectively an individual's reaction to viewing violence might make it possible to judge the likely social impact of violent films and television programmes. PMID:4730188

  12. The United Nations Environment Programme.

    ERIC Educational Resources Information Center

    Miller, Norman N.

    1979-01-01

    Described is the history of the United Nations Environment Programme (UNEP) since its formation in 1972. Also included is an examination of UNEP's major programs and projects, and an assessment of the organization's problems and future prospects. The function of UNEP is to coordinate the management and assessment of the world's environment by…

  13. Portugal's Secondary School Modernisation Programme

    ERIC Educational Resources Information Center

    Heitor, Teresa V.; Freire da Silva, Jose M. R.

    2009-01-01

    The aim of the Secondary School Modernisation Programme, being implemented in Portugal by "Parque Escolar, EPE", is based on the pursuit of quality and makes Portuguese education a potential international benchmark. This paper discusses the strategies adopted to reorganise school spaces. It describes the conceptual model and highlights the…

  14. Code Description 0 General Programmes

    E-print Network

    Costagliola, Gennaro

    524 Chemical and process 525 Motor vehicles, ships and aircraft 529 Engineering and engineering trades, Manufacturing and Construction 52 Engineering and engineering trades 520 Engineering and engineering trades (others) 54 Manufacturing and processing 540 Manufacturing and processing (broad programmes) 541 Food

  15. Trevor Henthorn Programmer Analyst III

    E-print Network

    Gleeson, Joseph G.

    , to a large set of systems including recording studios, electronic music studios, theatrical lighting control, teaching electronic music and recording technology. He has also created an internship program for manyTrevor Henthorn Programmer Analyst III Academic Affairs: Music Trevor Henthorn graduated from UCSD

  16. Implementing a Successful Laptop Programme.

    ERIC Educational Resources Information Center

    Westwood, Pete; Dobson, Lindsey

    1999-01-01

    Describes experiences in instituting a personal ownership laptop programme for 10 and 11 year-olds. Argues that learning with laptops captivates and empowers students, making them more self-motivated and task-oriented. There is increased risk-taking, as students work at their own pace, and in their own time. Furthermore, creativity is encouraged.…

  17. The Massey Kiwi Friend Programme

    ERIC Educational Resources Information Center

    Ramsey, Philip; Ramsey, Deborah; Mason, Robyn

    2007-01-01

    Like many institutions, Massey University has experienced growth in enrolments of international students. Increasing numbers of international students has led to frustrations for international and domestic students, and for staff. This paper describes an innovative programme designed to help with the orientation of international students. Domestic…

  18. PROGRAMMING MULTICORES: DO APPLICATIONS PROGRAMMERS

    E-print Network

    Sendag, Resit

    AND KESHAV PINGALI DEBATE WHETHER EXPLICITLY PARALLEL PROGRAMMING IS A NECESSARY EVIL FOR APPLICATIONS programmers need to write explicitly parallel programs? Most people be- lieve that the current method of the message passing in- terface (MPI), experts were concerned that people would not be able to write parallel

  19. PROGRAMMING MULTICORES: DO APPLICATIONS PROGRAMMERS

    E-print Network

    August, David

    AND KESHAV PINGALI DEBATE WHETHER EXPLICITLY PARALLEL PROGRAMMING IS A NECESSARY EVIL FOR APPLICATIONS programmers need to write explicitly parallel programs? Most people be- lieve that the current method), experts were concerned that people would not be able to write parallel programs at all because humans

  20. DIGITAL Visual Fortran Programmer's Guide

    E-print Network

    DIGITAL Visual Fortran Programmer's Guide Date: September, 1997 Software Version: DIGITAL Visual on Intel® Systems Microsoft Windows NT on Windows 95® Systems Digital Equipment Corporation Maynard, Massachusetts 1 of 1 9/4/97 3:15 PM #12;Copyright Page Digital Equipment Corporation makes no representations

  1. DIGITAL Visual Fortran Programmer's Guide

    E-print Network

    DIGITAL Visual Fortran Programmer's Guide Date: December, 1998 Software Version: DIGITAL Visual 98, or Windows NT® Version 4 Digital Equipment Corporation Maynard, Massachusetts #12;Copyright Page Digital Equipment Corporation makes no representations that the use of its products in the manner

  2. Tech & Trends TV-Programm

    E-print Network

    Wang, James Z.

    Porno-Sites Strapse und viel Haut vielleicht bald unter ".xxx". 18. September 1997 (tk) Das Policy/gTLD-MoU"), will alle Porno- und Sex-Sites mit der gleichen Top-Level-Domain kennzeichnen. Damit reagieren die Komitee-Elite-Universität Harvard mit einem neuen Porno-Schutz-Programm Kinder vor Schmuddel-Kram aus dem Internet zu schützen. Das

  3. Masters programmes taught in English

    E-print Network

    in the chemical and pharmaceutical industries Environmental management positions in industry and with government of pharmaceutical engineering. Also the future chemical industry requires cleaner, highly sustainable and moreMaster´s programmes taught in English Chemical and Pharmaceutical Engineering Technical Chemistry

  4. Simulation of a sprinter. Part II. Implementation on a programmable calculator.

    PubMed

    Vaughan, C L

    1983-01-01

    Although successful models have been developed to simulate a sprinter's performance, they are often complex and sophisticated, requiring a main frame environment and expensive monitoring equipment. These disadvantages preclude the wide-spread use of the models by practitioners. This paper presents a method in which the necessary data can be easily gathered--using a tape measure, six stop watches and bollards, a starting gun, and a bathroom scale. A simple algorithm is presented for calculating the parameters of a previously defined model, and implemented on hand-held programmable calculators, the Casio FX-502P and HP41C. The model calculates the sprinter's initial horizontal acceleration, maximum horizontal velocity and can be used to predict the time for any given race distance. The model can therefore be used to evaluate the sprinter's current performance as well as indicate his potential if he were able to reach and maintain maximum velocity. PMID:6687467

  5. 21 CFR 870.3700 - Pacemaker programmers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Prosthetic Devices § 870.3700 Pacemaker programmers. (a) Identification. A pacemaker programmer is a device used...

  6. Visual discomfort under various brightness conditions using eye movements in watching stereoscopic 3D video

    NASA Astrophysics Data System (ADS)

    Cho, Sang-Hyun; Kang, Hang-Bong

    2014-03-01

    Visual discomfort is caused by various factors when watching stereoscopic 3D contents. In particular, brightness change is known as one of the major factors related to visual discomfort. However, most previous research about visual discomfort dealt with binocular disparity as related to accommodation and vergence linkage. In this paper, we analyze visual discomfort caused by brightness change using eye-movements and a subjective test. Eye-movements are computed using eye pupil motion as detected from a near-infrared eye image. We measure eye-blinking and pupil size while watching stereoscopic 3D videos with global and local brightness variations. The results show that viewers felt more visual discomfort in local change than in global change of brightness in a scene.

  7. Reading Books and Watching Films as a Protective Factor against Suicidal Ideation.

    PubMed

    Kasahara-Kiritani, Mami; Hadlaczky, Gergö; Westerlund, Michael; Carli, Vladimir; Wasserman, Camilla; Apter, Alan; Balazs, Judit; Bobes, Julio; Brunner, Romuald; McMahon, Elaine M; Cosman, Doina; Farkas, Luca; Haring, Christian; Kaess, Michael; Kahn, Jean-Pierre; Keeley, Helen; Nemes, Bogdan; Mars Bitenc, Urša; Postuvan, Vita; Saiz, Pilar; Sisask, Merike; Värnik, Airi; Sarchiapone, Marco; Hoven, Christina W; Wasserman, Danuta

    2015-01-01

    Reading books and watching films were investigated as protective factors for serious suicidal ideation (SSI) in young people with low perceived social belonging. Cross-sectional and longitudinal (12-month) analyses were performed using data from a representative European sample of 3256 students from the "Saving and Empowering Young Lives in Europe" study. Low social belonging was associated to SSI. However, reading books and watching films moderated this association, especially for those with lowest levels of belonging. This was true both at baseline and at 12 months of follow-up analyses. These media may act as sources of social support or mental health literacy and thus reduce the suicide risk constituted by low sense of belonging. PMID:26694431

  8. Reading Books and Watching Films as a Protective Factor against Suicidal Ideation

    PubMed Central

    Kasahara-Kiritani, Mami; Hadlaczky, Gergö; Westerlund, Michael; Carli, Vladimir; Wasserman, Camilla; Apter, Alan; Balazs, Judit; Bobes, Julio; Brunner, Romuald; McMahon, Elaine M.; Cosman, Doina; Farkas, Luca; Haring, Christian; Kaess, Michael; Kahn, Jean-Pierre; Keeley, Helen; Nemes, Bogdan; Mars Bitenc, Urša; Postuvan, Vita; Saiz, Pilar; Sisask, Merike; Värnik, Airi; Sarchiapone, Marco; Hoven, Christina W.; Wasserman, Danuta

    2015-01-01

    Reading books and watching films were investigated as protective factors for serious suicidal ideation (SSI) in young people with low perceived social belonging. Cross-sectional and longitudinal (12-month) analyses were performed using data from a representative European sample of 3256 students from the “Saving and Empowering Young Lives in Europe” study. Low social belonging was associated to SSI. However, reading books and watching films moderated this association, especially for those with lowest levels of belonging. This was true both at baseline and at 12 months of follow-up analyses. These media may act as sources of social support or mental health literacy and thus reduce the suicide risk constituted by low sense of belonging. PMID:26694431

  9. The New Product Watch: Successes and Challenges of Crowdsourcing as a Method of Surveillance.

    PubMed

    Nyman, Amy L; Biener, Lois

    2016-01-01

    New smokeless tobacco (eg, snus and dissolvable tobacco products) and nontobacco nicotine products (eg, e-cigarettes) have emerged in recent years amid widespread speculation about locations of test marketing, toxic constituents, and consumer targeting. The New Product Watch was a pilot online monitoring system aimed at filling these information gaps by using a form of crowdsourcing: recruiting volunteers to visit local retailers and report their findings. With very little funding, the New Product Watch gathered county-specific data on new product availability in 19 states as well as trend data on product marketing and demand, and completed 2 rounds of product purchases and subsequent toxic constituent analyses. Data were collected over a 2-year period, between 2009 and 2011. Despite the successes, we found that this small-scale, volunteer effort was not a sustainable method for ensuring continuous, systematic surveillance of new product availability, marketing, and toxicity. PMID:24335713

  10. CORRELATION OF DNA METHYLATION WITH MERCURY CONTAMINATION IN MARINE ORGANISMS: A CASE STUDY OF NOAA MUSSEL WATCH TISSUE SAMPLES 

    E-print Network

    Brinkmeyer, Robin; Taylor, Robert; Germ, Kaylyn E.

    2011-08-04

    American oysters (Crassostrea virginica) obtained from the NOAA Mussel Watch program were screened for DNA methylation, a type of epigenetic response to stressors. Oysters were collected from sites in the Gulf of Mexico having high mercury...

  11. Programmation Web Sites dynamiques et langage PHP

    E-print Network

    Lacroix, Mathieu

    Programmation Web Sites dynamiques et langage PHP Mathieu Lacroix I.U.T. de Villetaneuse Année 2015/ ~lacroix/ Mathieu Lacroix Programmation Web 1 / 77 #12;Plan 1 Rappels 2 Sites dynamiques 3 Langage PHP 4 Compléments Mathieu Lacroix Programmation Web 2 / 77 #12;Plan 1 Rappels 2 Sites dynamiques 3 Langage PHP 4

  12. Programmation Web Sites dynamiques et langage PHP

    E-print Network

    Lacroix, Mathieu

    Programmation Web Sites dynamiques et langage PHP Mathieu Lacroix I.U.T. de Villetaneuse Année 2014/ ~lacroix/ Mathieu Lacroix Programmation Web 1 / 75 #12;Plan 1 Rappels 2 Sites dynamiques 3 Langage PHP 4 Compléments Mathieu Lacroix Programmation Web 2 / 75 #12;Plan 1 Rappels 2 Sites dynamiques 3 Langage PHP 4

  13. Degree Entry Programme Design Studies Key details

    E-print Network

    Painter, Kevin

    Degree Entry Programme Design Studies Key details Duration: 2 semesters (full-time) Delivery type: Day Intake date: September, January Fees: 38000 AED Overview This programme is designed to provide students with a pathway into an undergraduate degree programme in the School of Textiles and Design

  14. Director's Foreword Brief Scientific Report on Programmes

    E-print Network

    Page Director's Foreword Brief Scientific Report on Programmes Introducing Sir David Wallace Recent and Future Programmes Scientific Steering Committee Scientific Policy Statement Programme Participation Young community in the UK. The concept of bringing the best international mathematical scientists to work together

  15. Tuition Fees 2015-16 Undergraduate Programmes

    E-print Network

    Chittka, Lars

    -sessional English language courses 2 Foundation programmes 2 Diploma programmes 2 Students in Year 1 in Oral Health Education (part-time) £850 £2,250 Y2GE International Foundation Programme in Humanities Sciences £9,000 £16,950 NN12 BSc Business Management £9,000 £15,000 A200 BDS Dentistry (Year 1) £9,000 £30

  16. School Security Assessment Programme in Australia

    ERIC Educational Resources Information Center

    Marrapodi, John

    2007-01-01

    This article describes a successful security risk management programme in Australia. The state-wide programme follows a structured risk management approach focusing on the safety and security of people, information, provision, and assets in the school environment. To assist school principals, a Security Risk Assessment Programme was developed on a…

  17. Stakeholder Perspectives: CLIL Programme Management in Estonia

    ERIC Educational Resources Information Center

    Mehisto, Peeter; Asser, Hiie

    2007-01-01

    In 2000, Estonia launched a voluntary Estonian language CLIL programme for seven year-olds in four Russian-medium schools. The programme has expanded rapidly to a total of 48 kindergartens and schools. This paper reports on research into stakeholder perspectives on programme management. In addition to surveying parents, teachers, vice-principals…

  18. Eye Movements While Watching Narrative Film: A Dissociation of Eye Movements and Comprehension.

    PubMed

    Hutson, John; Smith, Tim; Magliano, Joseph; Heidebrecht, Grace; Hinkel, Thomas; Tang, Jia Li; Loschky, Lester

    2015-09-01

    During reading there is a strong relationship between eye-movements and comprehension, but does this extend to the ubiquitous activity of watching movies? In four experiments we tested two competing hypotheses: H1) Mental Model: viewers' narrative comprehension guides their visual attention, versus H2) Tyranny of Film: Attentional synchrony across viewers washes out comprehension-based differences in attention. We tested these hypotheses by manipulating comprehension through the presence/absence of context while participants watched a clip from "Touch of Evil" (Welles, 1958): the Context condition saw a bomb put in a car to begin the clip, which the No-context condition did not see. We measured comprehension by having participants predict what would happen next after watching the clip. Experiment 1 established a strong comprehension difference; only the Context condition predicted the car exploding. Experiment 2, which added eyetracking, replicated the comprehension difference, but found no differences in eye movements in either attentional synchrony or looking at the car. Experiments 3 and 4 altered the perceived protagonist of the clip by what was shown first: the Context condition still saw the bomb and car first (i.e., car passengers = protagonists), but the No-context began watching later, first seeing a couple walking (i.e., couple = protagonists) and the car temporarily off-screen. Experiment 3 again showed the comprehension difference and overall eye movement similarity; however, when the No-context condition later first saw the car, they looked at it less than the Context condition. Experiment 4 measured on-line comprehension by having participants press a button whenever they perceived a new event. Results showed large differences in comprehension-the No-context condition perceived more events-thus demonstrating substantial differences in comprehension using two qualitatively different measures. However, these comprehension differences minimally affected eye-movements, with one small difference when the protagonist was manipulated, thus generally supporting the Tyranny of Film hypothesis. Meeting abstract presented at VSS 2015. PMID:26325804

  19. Star Watch: The Amateur Astronomer's Guide to Finding, Observing, and Learning about Over 125 Celestial Objects

    NASA Astrophysics Data System (ADS)

    Harrington, Philip S.

    2003-07-01

    Your Passport to the Universe The night sky is alive with many wonders--distant planets, vast star clusters, glowing nebulae, and expansive galaxies, all waiting to be explored. Let respected astronomy writer Philip Harrington introduce you to the universe in Star Watch, a complete beginner's guide to locating, observing, and understanding these celestial objects. You'll start by identifying the surface features of the Moon, the banded cloud tops of Jupiter, the stunning rings of Saturn, and other members of our solar system. Then you'll venture out beyond our solar system, where you'll learn tips and tricks for finding outstanding deep-sky objects from stars to galaxies, including the entire Messier catalog--a primary goal of every serious beginner. Star Watch features a detailed physical description of each target, including size, distance, and structure, as well as concise directions for locating the objects, handy finder charts, hints on the best times to view each object, and descriptions of what you'll really see through a small telescope or binoculars and with the naked eye. Star Watch will transport you to the farthest depths of space--and return you as a well-traveled, experienced stargazer.

  20. Viewers vs. doers. The relationship between watching food television and BMI.

    PubMed

    Pope, Lizzy; Latimer, Lara; Wansink, Brian

    2015-07-01

    The objective of this study was to examine where nutritional gatekeepers obtain information about new foods, and whether information source is associated with Body Mass Index (BMI), as well as whether any association varied according to how often the participant cooked from scratch. A national panel survey of 501 females aged 20-35 assessed how participants obtained information on new recipes, and asked a series of questions about their cooking habits, their weight and height. Linear regressions were run to determine associations between information source, cooking from scratch, and BMI. Obtaining information from cooking shows was positively correlated with BMI (p?<0.05), as was obtaining information from social media (p?<0.05), whereas obtaining information from other print, online, or in-person sources was not significantly associated with BMI. A significant interaction between watching cooking shows and cooking from scratch indicated that cooking from scratch, as well as watching cooking shows was associated with higher BMI (p?<0.05). Obtaining information about new foods from television cooking shows or social media - versus other sources - appears to have a unique relationship with BMI. Furthermore, watching cooking shows may have a differential effect on BMI for those who are merely TV "viewers," versus those who are "doers." Promoting healthy foods on cooking shows may be one way to positively influence the weight status of "doers" as well as "viewers." PMID:25747286

  1. Kinematics of Liquid Crystal used in LCD Screens of Sport's Watches

    NASA Astrophysics Data System (ADS)

    Sharma, Dipti; Iannacchione, Germano

    2006-10-01

    Properties of phase transitions of liquid crystals are used to manufacture LCD screens of watches and TVs. The kinematics of phase transitions of bulk liquid crystals pay vital role to understand the thermodynamic behavior of liquid crystals which further can be used in LCD screens of watches. Here we present the kinematics of phase transitions of bulk liquid crystal octylcyanobiphenyl (8CB) using calorimetry technique. Bulk 8CB was studied at different heating scan rates from 20 to 0.5 K/min for heating and cooling scans. Transition peaks, observed at the melting/crystallization, smectic-A to nematic (SmA-N), and nematic to isotropic (N-I) transitions, showed significant temperature shift in respective peaks with different scan rates following an Arrhenius behavior. The activation energy of a transition increases as the total energy involved in the transition decreases. The more enthalpy or latent heat involved in the transition belongs to less activation energy of the transition. This shows the significance of the 1^st order transition as a transition from N to I, and needs less activation than 2^nd order transition from SmA to N transition and hence liquid crystal is more used in this transition range for LCD screens of watches.

  2. Treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment

    SciTech Connect

    Young, R.C.; Longo, D.L.; Glatstein, E.; Ihde, D.C.; Jaffe, E.S.; DeVita, V.T. Jr.

    1988-04-01

    Patients with advanced indolent lymphoma often have long survival (median, 4 to 8 years) in spite of frequent relapses. The inability of combination chemotherapy or radiation therapy (RT) to render patients disease free has led to radically divergent treatment approaches. Initial treatment may vary from aggressive combined modality therapy to no initial treatment. We sought to evaluate these two divergent approaches in a randomized trial of advanced indolent lymphomas (nodular, poorly differentiated lymphocytic; nodular mixed; diffuse, well-differentiated lymphocytic; diffuse, intermediately differentiated lymphocytic; and diffuse, poorly differentiated lymphocytic). A total of 104 patients were entered: 44 were randomly assigned to watch and wait in which only carefully defined, limited RT was administered if necessary; 45 were randomly assigned to aggressive combined modality treatment with prednisone, methotrexate, doxorubicin, cyclophosphamide, plus etoposide plus mechlorethamine, vincristine, procarbazine, prednisone (ProMACE-MOPP), followed by total nodal irradiation (TNI); and 15, with symptoms requiring initial therapy, received the identical combined treatment but were not randomly assigned. Of 41 evaluable patients on watch and wait, 23 (56%) have still not required systemic therapy, although 16 (39%) have received limited RT. Median time to crossover was 34 months. Of 18 patients crossed over, seven of the 16 who completed therapy (43%) achieved CR; two (11%) have relapsed. Histologic progression was seen in six (15%) of 41 patients on watch and wait without intervening chemotherapy. Of 45 patients randomly assigned to chemotherapy, 37 (82%) have completed induction therapy, and 29 of the 37 (78%) achieved CR.

  3. Visual fatigue caused by watching 3DTV: an fMRI study

    PubMed Central

    2015-01-01

    The objective of this study is to observe the visual fatigue caused by watching 3DTV using the method of functional magnetic resonance imaging (fMRI). The data of fMRI during three kinds of visual stimulation tasks were obtained from twenty subjects. At first, blood-oxygen-level dependent (BOLD) signal changes during stimuli of checkerboard task were compared before and after one-hour watching 3D/2DTV, and subjective evaluation was conducted based on the questionnaire simultaneously. Then 3D and 2D images were used to stimulate healthy individuals to measure brain activities that correlated with stereoscopic vision. Finally, the relationship between front or back depth of field images and visual fatigue was investigated. The results reveal that the 3D group shows more significant differences of brain activities in BA8, BA17, BA18 and BA19 than the 2D group during the checkerboard stimulation. BA5, BA6, BA7 and BA8 were testified to have close relationship with stereoscopic perception via the 2D/3D images stimulation. Furthermore, the front depth of field image was proven to impose a more serious impact on visual fatigue than the back one. These conclusions are useful for healthy and reasonable 3DTV watching as well as properly designing of 3D scenes. PMID:25603496

  4. Correlation between Inter-Blink Interval and Episodic Encoding during Movie Watching

    PubMed Central

    Shin, Young Seok; Chang, Won-du; Park, Jinsick; Im, Chang-Hwan; Lee, Sang In; Kim, In Young; Jang, Dong Pyo

    2015-01-01

    Human eye blinking is cognitively suppressed to minimize loss of visual information for important real-world events. Despite the relationship between eye blinking and cognitive state, the effect of eye blinks on cognition in real-world environments has received limited research attention. In this study, we focused on the temporal pattern of inter-eye blink interval (IEBI) during movie watching and investigated its relationship with episodic memory. As a control condition, 24 healthy subjects watched a nature documentary that lacked a specific story line while electroencephalography was performed. Immediately after viewing the movie, the subjects were asked to report its most memorable scene. Four weeks later, subjects were asked to score 32 randomly selected scenes from the movie, based on how much they were able to remember and describe. The results showed that the average IEBI was significantly longer during the movie than in the control condition. In addition, the significant increase in IEBI when watching a movie coincided with the most memorable scenes of the movie. The results suggested that the interesting episodic narrative of the movie attracted the subjects’ visual attention relative to the documentary clip that did not have a story line. In the episodic memory test executed four weeks later, memory performance was significantly positively correlated with IEBI (p<0.001). In summary, IEBI may be a reliable bio-marker of the degree of concentration on naturalistic content that requires visual attention, such as a movie. PMID:26529091

  5. The Archive of the Amateur Observation Network of the International Halley Watch. Volume 2; Comet Halley

    NASA Technical Reports Server (NTRS)

    Edberg, Stephen J. (Editor)

    1996-01-01

    The International Halley Watch (IHW) was organized for the purpose of gathering and archiving the most complete record of the apparition of a comet, Halley's Comet (1982i = 1986 III = 1P/Halley), ever compiled. The redirection of the International Sun-Earth Explorer 3 (ISEE-3) spacecraft, subsequently renamed the International Cometary Explorer (ICE), toward Comet Giacobini- Zinner (1984e = 1985 XIII = 21P/Giacobini-Zinner) prompted the initiation of a formal watch on that comet. All the data collected on P/Giacobini-Zinner and P/Halley have been published on CD-ROM in the Comet Halley Archive. This document contains a printed version of the archive data, collected by amateur astronomers, on these two comets. Volume 1 contains the Comet Giacobini-Zinner data archive and Volume 2 contains the Comet Halley archive. Both volumes include information on how to read the data in both archives, as well as a history of both comet watches (including the organizing of the network of astronomers and lessons learned from that experience).

  6. The JOSHUA (J80) system programmer`s manual

    SciTech Connect

    Smetana, A.O.; McCort, J.T.; Westmoreland, B.W.

    1993-08-01

    The JOSHUA system routines (JS routines) can be used to manage a JOSHUA data base and execute JOSHUA modules on VAX/VMS and IBM/MVS computer systems. This manual provides instructions for using the JS routines and information about the internal data structures and logic used by the routines. It is intended for use primarily by JOSHUA systems programmers, however, advanced applications programmers may also find it useful. The JS routines are, as far as possible, written in ANSI FORTRAN 77 so that they are easily maintainable and easily portable to different computer systems. Nevertheless, the JOSHUA system provides features that are not available in ANSI FORTRAN 77, notably dynamic module execution and a data base of named, variable length, unformatted records, so some parts of the routines are coded in nonstandard FORTRAN or assembler (as a last resort). In most cases, the nonstandard sections of code are different for each computer system. To make it easy for programmers using the JS routines to avoid naming conflicts, the JS routines and common block all have six character names that begin with the characters {open_quotes}JS.{close_quotes} Before using this manual, one should be familiar with the JOSHUA system as described in {open_quotes}The JOSHUA Users` Manual,{close_quotes} ANSI FORTRAN 77, and at least one of the computer systems for which the JS routines have been implemented.

  7. The Physics Programme at Superb

    NASA Astrophysics Data System (ADS)

    Bevan, Adrian

    2013-11-01

    SuperB is a next generation high luminosity e+e- collider that will be built at the Cabibbo Laboratory, Tor Vergata, in Italy. The physics goals of this experiment are to search for signs of physics beyond the Standard Model through precision studies of rare or forbidden processes. While the name suggests that B physics is the main goal, this experiment is a Super Flavour Factory, and precision measurements of Bu,d,s, D, ?, ?, and ?(3770) decays as well as spectroscopy and exotica searches form part of a broad physics programme. In addition to searching for new physics (NP) in the form of heavy particles, or violations of laws of physics, data from SuperB will be able to perform precision tests of the Standard Model. I will briefly review of some highlights of the SuperB physics programme.

  8. Designing Efficient Programmable Quantum Circuits

    E-print Network

    Anmer Daskin; Ananth Grama; Giorgos Kollias; Sabre Kais

    2012-07-22

    Constructing general programmable circuits to be able to run any given unitary operator efficiently on a quantum processor is of fundamental importance. We present a new quantum circuit design technique resulting two general programmable circuit schemes. The circuit schemes can be used to simulate any given operator by setting the angle values in the circuit. This provides a fixed circuit design whose angles are determined from the elements of the given matrix, which can be non-unitary, in an efficient way. We also give both classical and quantum complexity analysis for these circuits and show that the circuits require a few classical computations, and the quantum complexities of them are almost the same as non-general circuits.

  9. Learning to Watch Cinema in the Classroom: Production and Investigation for the Teaching of Cinematographic Language

    ERIC Educational Resources Information Center

    Goncalves, Ana Luisa; Fandos, Manuel; Aguaded, Jose-Ignacio

    2011-01-01

    This article synthesises an investigation of the making of a didactic programme as a consequence of the excess of consumption of audiovisual messages and the non critical and non-thoughtful attitude the youngsters have towards it. As an answer to this problem, the authors have produced a didactical programme about cinema and its language, the main…

  10. Programmable data collection platform study

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The results of a feasibility study incorporating microprocessors in data collection platforms in described. An introduction to microcomputer hardware and software concepts is provided. The influence of microprocessor technology on the design of programmable data collection platform hardware is discussed. A standard modular PDCP design capable of meeting the design goals is proposed, and the process of developing PDCP programs is examined. A description of design and construction of the UT PDCP development system is given.

  11. Programmable Multi-Chip Module

    DOEpatents

    Kautz, David (Lenexa, KS); Morgenstern, Howard (Lee's Summit, MO); Blazek, Roy J. (Overland Park, KS)

    2004-11-16

    A multi-chip module comprising a low-temperature co-fired ceramic substrate having a first side on which are mounted active components and a second side on which are mounted passive components, wherein this segregation of components allows for hermetically sealing the active components with a cover while leaving accessible the passive components, and wherein the passive components are secured using a reflow soldering technique and are removable and replaceable so as to make the multi-chip module substantially programmable with regard to the passive components.

  12. Programmable Automated Welding System (PAWS)

    NASA Technical Reports Server (NTRS)

    Kline, Martin D.

    1994-01-01

    An ambitious project to develop an advanced, automated welding system is being funded as part of the Navy Joining Center with Babcock & Wilcox as the prime integrator. This program, the Programmable Automated Welding System (PAWS), involves the integration of both planning and real-time control activities. Planning functions include the development of a graphical decision support system within a standard, portable environment. Real-time control functions include the development of a modular, intelligent, real-time control system and the integration of a number of welding process sensors. This paper presents each of these components of the PAWS and discusses how they can be utilized to automate the welding operation.

  13. Programmable, automated transistor test system

    NASA Technical Reports Server (NTRS)

    Truong, L. V.; Sundburg, G. R.

    1986-01-01

    A programmable, automated transistor test system was built to supply experimental data on new and advanced power semiconductors. The data will be used for analytical models and by engineers in designing space and aircraft electric power systems. A pulsed power technique was used at low duty cycles in a nondestructive test to examine the dynamic switching characteristic curves of power transistors in the 500 to 1000 V, 10 to 100 A range. Data collection, manipulation, storage, and output are operator interactive but are guided and controlled by the system software.

  14. Seagrass-Watch: Engaging Torres Strait Islanders in marine habitat monitoring

    NASA Astrophysics Data System (ADS)

    Mellors, Jane E.; McKenzie, Len J.; Coles, Robert G.

    2008-09-01

    Involvement in scientifically structured habitat monitoring is a relatively new concept to the peoples of Torres Strait. The approach we used was to focus on awareness, and to build the capacity of groups to participate using Seagrass-Watch as the vehicle to provide education and training in monitoring marine ecosystems. The project successfully delivered quality scientifically rigorous baseline information on the seasonality of seagrasses in the Torres Strait—a first for this region. Eight seagrass species were identified across the monitoring sites. Seagrass cover varied within and between years. Preliminary evidence indicated that drivers for seagrass variability were climate related. Generally, seagrass abundance increased during the north-west monsoon ( Kuki), possibly a consequence of elevated nutrients, lower tidal exposure times, less wind, and higher air temperatures. Low seagrass abundance coincided with the presence of greater winds and longer periods of exposure at low tides during the south-east trade wind season ( Sager). No seasonal patterns were apparent when frequency of disturbance from high sedimentation and human impacts was high. Seagrass-Watch has been incorporated in to the Thursday Island High School's Marine Studies Unit ensuring continuity of monitoring. The students, teachers, and other interested individuals involved in Seagrass-Watch have mastered the necessary scientific procedures to monitor seagrass meadows, and developed skills in coordinating a monitoring program and skills in mentoring younger students. This has increased the participants' self-esteem and confidence, and given them an insight into how they may participate in the future management of their sea country.

  15. A graduate programme for academic family physicians.

    PubMed

    Brennan, M; McWhinney, I R; Stewart, M; Weston, W

    1985-09-01

    The paper describes a graduate studies programme designed to prepare outstanding family physicians for academic leadership and reports an evaluation of the programme. The programme aims to produce academic family physicians who exhibit certain qualities: outstanding clinical skills, professional interest in the organization and transmission of knowledge, and a scholarly approach through research and skills of leadership. The course includes clinical and teaching practice, formal course work and a scholarly thesis; the emphasis is on teaching and learning, theoretical foundations of family medicine, whole person medicine, research design and techniques, ethical decision making, and administration of organizations. A survey of the first 30 graduates of the programme indicated that the majority did more clinical teaching, small group teaching, research, writing and administration than before the course. The graduates' opinions of the programme indicated the extent to which the programme goals have been met; to provide a coherent learning experience integrating the art, science and technology of the discipline of family medicine. PMID:4043606

  16. Forest Watch: Using Student Data to Monitor Forest Response to Ground-Level Ozone

    NASA Astrophysics Data System (ADS)

    Spencer, S.; Rock, B. N.

    2006-12-01

    Forest Watch, a k-12 science outreach program begun at the University of New Hampshire (UNH) in 1991, has engaged pre-college students in providing UNH researchers with data on the annual response of white pine (Pinus strobus; a bio-indicator species for ozone exposure) to ground-level ozone across the New England region. Each year, student-collected growth and foliar symptomology data for 5 pine trees adjacent to their schools, along with first-year foliar samples, are submitted to UNH. Key foliar symptoms and student data are compared with summer monthly (JJA) maximum ozone concentrations collected by state and federal ozone monitoring stations across the region. To date, tree health indicators are inversely correlated (r2=0.83;p=0.10) with ozone concentrations: low ozone levels correlate with symptoms of good health (spectral indices diagnostic of high foliar chlorophyll levels and moisture content, normal incremental growth, low number of foliar symptoms), while summers characterized by high ozone concentrations correlate with symptoms of reduced health (low chlorophyll indices and moisture content, reduced incremental growth, increased number of foliar symptoms). In drought years (1999, 2001, 2002, 2003) few foliar symptoms of ozone damage are seen even though ozone levels were high, likely due to drought-induced stomatal closure. Based on student data since 1998, either low ozone summers, or drought summers have resulted in improved health in the sampled trees (n=30). Based on the success of Forest Watch in New England, we are exploring the extension of the program to Colorado as Front Range Forest Watch, operated from Colorado State University (CSU). The primary objective is to develop a student-scientist-local agency project that addresses real ecological issues in northern Colorado, including ozone pollution, and to provide pre-college students and teachers authentic science experiences. CSU runs a GK-12 program with Poudre School District in northern Colorado, which infuses ecology graduate students into the public school system to assist in the delivery of science content. The extension of Forest Watch to northern Colorado will provide a test-bed for the possible extension of the program to the rest of the state.

  17. Network-Level Connectivity Dynamics of Movie Watching in 6-Year-Old Children

    PubMed Central

    Emerson, Robert W.; Short, Sarah J.; Lin, Weili; Gilmore, John H.; Gao, Wei

    2015-01-01

    Better understanding of the developing brain’s functional mechanisms is critical for improving diagnosis and treatment of different developmental disorders. Particularly, characterizing how the developing brain dynamically reorganizes during different cognitive states may offer novel insight into the neuronal mechanisms of cognitive deficits. Imaging the brain during naturalistic conditions, like movie watching, provides a highly practical way to study young children’s developing functional brain systems. In this study we compared the network-level functional organization of 6-year-old children while they were at rest with their functional connectivity as they watched short video clips. We employed both a data-driven independent component analysis (ICA) approach and a hypothesis-driven seed-based analysis to identify changes in network-level functional interactions during the shift from resting to video watching. Our ICA results showed that naturally watching a movie elicits significant changes in the functional connectivity between the visual system and the dorsal attention network when compared to rest (t(32) = 5.02, p = 0.0001). More interestingly, children showed an immature, but qualitatively adult-like, pattern of reorganization among three of the brain’s higher-order networks (frontal control, default-mode and dorsal attention). For both ICA and seed-based approaches, we observed a decrease in the frontal network’s correlation with the dorsal attention network (ICA: t(32) = ?2.46, p = 0.02; Seed-based: t(32) = ?1.62, p =0.12) and an increase in its connectivity with the default mode network (ICA: t(32) = 2.84, p = 0.008; Seed-based: t(32) = 2.28, p =0.03), which is highly consistent with the pattern observed in adults. These results offer improved understanding of the developing brain’s dynamic network-level interaction patterns during the transition between different brain states and call for further studies to examine potential alterations to such dynamic patterns in different developmental disorders. PMID:26635584

  18. Astronaut David Scott watching hammer and feather fall to lunar surface

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Astronaut David R. Scott, Apollo 15 commander, watches a geological hammer and a feather hit the lunar surface simultaneously in a test of Galileo's law of motion concerning falling bodies, as seen in this color reproduction taken from a transmission made by the RCA color television camera mounted on the Lunar Roving Vehicle. Scott released the hammer from his right hand and the feather from his left at the same instant. This experiment occured toward the end of the third and final lunar surface extravehicular activity.

  19. The use of transplanted mussels in the California State Mussel Watch Program

    SciTech Connect

    Stephenson, M.D.; Ichikawa, G.S.; Goetzl, J.

    1995-12-31

    Many contaminant programs have been established to study the geographical distributions of potential pollutants, but unfortunately, many have relied solely on resident bivalves. This approach limits the versatility of monitoring programs in that residents are not often found in all the places necessary to sample and there are factors which are inherent in using residents that confound the results. The California State Mussel Watch Program has relied heavily on transplants because they eliminate much of the variation inherent in using residents and they can be transplanted almost anywhere. Examples are given that demonstrate the advantages of using transplants over residents.

  20. This (Sandpiper like) bird, as well as many other species keep watch over Moffett Field wetlands.

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This (Sandpiper like) bird, as well as many other species keep watch over Moffett Field wetlands. The shorebird in this picture is a greater yellowlegs (Tinga melanoleuca) which is a common bird found in our coastal salt marsh and tidal zones in winter months. Generally, they summer/breed up north in Canada and Alaska and then migrate in the fall to winter along the west coast of the U.S. and Mexico. Known for their loud call of a slightly descending series of three or more tew notes. Diet consists of small fish, insects, snails, worms, and tadpoles. used in Ames 60 yr. History NASA SP-2000-4314

  1. EDAA20 Programmering och databaser Lsperiod 1

    E-print Network

    -2 programmering) HT 2014 5 / 48 #12;Exempel på en algoritm Problem: Beräkna summan av talen 12.5 och 0.7 och skriv EDAA20 (F1-2 programmering) HT 2014 6 / 48 #12;Exempel på programkod Problem: Beräkna summan av talen1 + nbr2; System.out.println("Summan av talen är " + sum); EDAA20 (F1-2 programmering) HT 2014 7

  2. Building a global business continuity programme.

    PubMed

    Lazcano, Michael

    2014-01-01

    Business continuity programmes provide an important function within organisations, especially when aligned with and supportive of the organisation's goals, objectives and organisational culture. Continuity programmes for large, complex international organisations, unlike those for compact national companies, are more difficult to design, build, implement and maintain. Programmes for international organisations require attention to structural design, support across organisational leadership and hierarchy, seamless integration with the organisation's culture, measured success and demonstrated value. This paper details practical, but sometimes overlooked considerations for building successful global business continuity programmes. PMID:24854730

  3. Ethical Issues for Community College Student Programmers.

    ERIC Educational Resources Information Center

    Friedrich, Sue

    2002-01-01

    Discusses examples of unique ethical issues faced by community college student programmers: member commitment, poor program attendance and lack of programming board diversity, and conflicts of interest (EV)

  4. PROGRAMMABLE CONTEXTUAL ANALYSIS David J. Ittner

    E-print Network

    Baird, Henry S.

    PROGRAMMABLE CONTEXTUAL ANALYSIS David J. Ittner Henry S. Baird AT&T Bell Laboratories 600 Mountain- guistics, information retrieval, string matching, numerical optimization, nat- ural language processing

  5. 21 CFR 870.3700 - Pacemaker programmers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Prosthetic Devices § 870.3700 Pacemaker programmers. (a) Identification. A...

  6. Programme and Module BSc Chemistry and Maths

    E-print Network

    Rzepa, Henry S.

    Programme and Module Handbook 2014-2015 BSc Chemistry and Maths BSc Natural Sciences MNatSc, BSc ........................................................................................................... 3 BSc Chemistry & Maths ......................................................................................................................... 5 BSc Chemistry & Maths (Industrial

  7. Trial Watch

    PubMed Central

    Aranda, Fernando; Vacchelli, Erika; Eggermont, Alexander; Galon, Jerome; Sautès-Fridman, Catherine; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Throughout the past 3 decades, along with the recognition that the immune system not only influences oncogenesis and tumor progression, but also determines how established neoplastic lesions respond therapy, renovated enthusiasm has gathered around the possibility of using vaccines as anticancer agents. Such an enthusiasm quickly tempered when it became clear that anticancer vaccines would have to be devised as therapeutic, rather than prophylactic, measures, and that malignant cells often fail to elicit (or actively suppress) innate and adaptive immune responses. Nonetheless, accumulating evidence indicates that a variety of anticancer vaccines, including cell-based, DNA-based, and purified component-based preparations, are capable of circumventing the poorly immunogenic and highly immunosuppressive nature of most tumors and elicit (at least under some circumstances) therapeutically relevant immune responses. Great efforts are currently being devoted to the identification of strategies that may provide anticancer vaccines with the capacity of breaking immunological tolerance and eliciting tumor-associated antigen-specific immunity in a majority of patients. In this sense, promising results have been obtained by combining anticancer vaccines with a relatively varied panels of adjuvants, including multiple immunostimulatory cytokines, Toll-like receptor agonists as well as inhibitors of immune checkpoints. One year ago, in the December issue of OncoImmunology, we discussed the biological mechanisms that underlie the antineoplastic effects of peptide-based vaccines and presented an abundant literature demonstrating the prominent clinical potential of such an approach. Here, we review the latest developments in this exciting area of research, focusing on high-profile studies that have been published during the last 13 mo and clinical trials launched in the same period to evaluate purified peptides or full-length proteins as therapeutic anticancer agents. PMID:24498550

  8. Weather Watch

    ERIC Educational Resources Information Center

    Bratt, Herschell Marvin

    1973-01-01

    Suggests a number of ways in which Federal Aviation Agency weather report printouts can be used in teaching the weather section of meteorology. These weather sequence reports can be obtained free of charge at most major airports. (JR)

  9. Trial Watch

    PubMed Central

    Vacchelli, Erika; Eggermont, Alexander; Sautès-Fridman, Catherine; Galon, Jérôme; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Toll-like receptors (TLRs) have long been known for their ability to initiate innate immune responses upon exposure to conserved microbial components such as lipopolysaccharide (LPS) and double-stranded RNA. More recently, this family of pattern recognition receptors has been attributed a critical role in the elicitation of anticancer immune responses, raising interest in the development of immunochemotherapeutic regimens based on natural or synthetic TLR agonists. In spite of such an intense wave of preclinical and clinical investigation, only three TLR agonists are currently licensed by FDA for use in cancer patients: bacillus Calmette–Guérin (BCG), an attenuated strain of Mycobacterium bovis that operates as a mixed TLR2/TLR4 agonist; monophosphoryl lipid A (MPL), a derivative of Salmonella minnesota that functions as a potent agonist of TLR4; and imiquimod, a synthetic imidazoquinoline that activates TLR7. One year ago, in the August and September issues of OncoImmunology, we described the main biological features of TLRs and discussed the progress of clinical studies evaluating the safety and therapeutic potential of TLR agonists in cancer patients. Here, we summarize the latest developments in this exciting area of research, focusing on preclinical studies that have been published during the last 13 mo and clinical trials launched in the same period to investigate the antineoplastic activity of TLR agonists. PMID:24083080

  10. Trial Watch

    PubMed Central

    Vacchelli, Erika; Vitale, Ilio; Tartour, Eric; Eggermont, Alexander; Sautès-Fridman, Catherine; Galon, Jérôme; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Radiotherapy has extensively been employed as a curative or palliative intervention against cancer throughout the last century, with a varying degree of success. For a long time, the antineoplastic activity of X- and ?-rays was entirely ascribed to their capacity of damaging macromolecules, in particular DNA, and hence triggering the (apoptotic) demise of malignant cells. However, accumulating evidence indicates that (at least part of) the clinical potential of radiotherapy stems from cancer cell-extrinsic mechanisms, including the normalization of tumor vasculature as well as short- and long-range bystander effects. Local bystander effects involve either the direct transmission of lethal signals between cells connected by gap junctions or the production of diffusible cytotoxic mediators, including reactive oxygen species, nitric oxide and cytokines. Conversely, long-range bystander effects, also known as out-of-field or abscopal effects, presumably reflect the elicitation of tumor-specific adaptive immune responses. Ionizing rays have indeed been shown to promote the immunogenic demise of malignant cells, a process that relies on the spatiotemporally defined emanation of specific damage-associated molecular patterns (DAMPs). Thus, irradiation reportedly improves the clinical efficacy of other treatment modalities such as surgery (both in neo-adjuvant and adjuvant settings) or chemotherapy. Moreover, at least under some circumstances, radiotherapy may potentiate anticancer immune responses as elicited by various immunotherapeutic agents, including (but presumably not limited to) immunomodulatory monoclonal antibodies, cancer-specific vaccines, dendritic cell-based interventions and Toll-like receptor agonists. Here, we review the rationale of using radiotherapy, alone or combined with immunomodulatory agents, as a means to elicit or boost anticancer immune responses, and present recent clinical trials investigating the therapeutic potential of this approach in cancer patients. PMID:24319634

  11. Trial Watch

    PubMed Central

    Vacchelli, Erika; Eggermont, Alexander; Fridman, Wolf Hervé; Galon, Jérôme; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    During the past two decades, the notion that cancer would merely constitute a cell-intrinsic disease has gradually been complemented by a model postulating that the immune system plays a relevant role during all stages of oncogenesis and tumor progression. Along with this conceptual shift, several strategies have been devised to stimulate tumor-specific immune responses, including relatively unselective approaches such as the systemic administration of adjuvants or immunomodulatory cytokines. One year ago, in the July issue of OncoImmunology, we described the main biological features of this large group of proteins and discussed the progress of ongoing clinical studies evaluating their safety and therapeutic potential in cancer patients. Here, we summarize the latest developments in this area of clinical research, focusing on high impact studies that have been published during the last 13 mo and clinical trials launched in the same period to investigate which cytokines can be employed as safe and efficient immunostimulatory interventions against cancer. PMID:24073369

  12. Nature Watch

    ERIC Educational Resources Information Center

    Sterling, Donna R.

    2010-01-01

    Children are naturally curious about the world in which they live. To focus this sense of wonder, have your students investigate their local habitat as it changes over the year. This multiseason study will build connections and add relevance to the habitats that children learn about. This series of activities for grades 4-6 explores the changing…

  13. Trial Watch

    PubMed Central

    Vacchelli, Erika; Aranda, Fernando; Eggermont, Alexander; Galon, Jérôme; Sautès-Fridman, Catherine; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    In 1997, for the first time in history, a monoclonal antibody (mAb), i.e., the chimeric anti-CD20 molecule rituximab, was approved by the US Food and Drug Administration for use in cancer patients. Since then, the panel of mAbs that are approved by international regulatory agencies for the treatment of hematopoietic and solid malignancies has not stopped to expand, nowadays encompassing a stunning amount of 15 distinct molecules. This therapeutic armamentarium includes mAbs that target tumor-associated antigens, as well as molecules that interfere with tumor-stroma interactions or exert direct immunostimulatory effects. These three classes of mAbs exert antineoplastic activity via distinct mechanisms, which may or may not involve immune effectors other than the mAbs themselves. In previous issues of OncoImmunology, we provided a brief scientific background to the use of mAbs, all types confounded, in cancer therapy, and discussed the results of recent clinical trials investigating the safety and efficacy of this approach. Here, we focus on mAbs that primarily target malignant cells or their interactions with stromal components, as opposed to mAbs that mediate antineoplastic effects by activating the immune system. In particular, we discuss relevant clinical findings that have been published during the last 13 months as well as clinical trials that have been launched in the same period to investigate the therapeutic profile of hitherto investigational tumor-targeting mAbs. PMID:24605265

  14. Trial Watch

    PubMed Central

    Aranda, Fernando; Vacchelli, Erika; Eggermont, Alexander; Galon, Jerome; Fridman, Wolf Hervé; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    Immunostimulatory monoclonal antibodies (mAbs) exert antineoplastic effects by eliciting a novel or reinstating a pre-existing antitumor immune response. Most often, immunostimulatory mAbs activate T lymphocytes or natural killer (NK) cells by inhibiting immunosuppressive receptors, such as cytotoxic T lymphocyte-associated protein 4 (CTLA4) or programmed cell death 1 (PDCD1, best known as PD-1), or by engaging co-stimulatory receptors, like CD40, tumor necrosis factor receptor superfamily, member 4 (TNFRSF4, best known as OX40) or TNFRSF18 (best known as GITR). The CTLA4-targeting mAb ipilimumab has been approved by the US Food and Drug Administration for use in patients with unresectable or metastatic melanoma in 2011. The therapeutic profile of ipilimumab other CTLA4-blocking mAbs, such as tremelimumab, is currently being assessed in subjects affected by a large panel of solid neoplasms. In the last few years, promising clinical results have also been obtained with nivolumab, a PD-1-targeting mAb formerly known as BMS-936558. Accordingly, the safety and efficacy of nivolumab and other PD-1-blocking molecules are being actively investigated. Finally, various clinical trials are underway to test the therapeutic potential of OX40- and GITR-activating mAbs. Here, we summarize recent findings on the therapeutic profile of immunostimulatory mAbs and discuss clinical trials that have been launched in the last 14 months to assess the therapeutic profile of these immunotherapeutic agents. PMID:24701370

  15. Trial watch

    PubMed Central

    Vacchelli, Erika; Aranda, Fernando; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Cremer, Isabelle; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    Tumor-targeting immune responses provide a significant contribution to (when they do not entirely account for) the clinical activity of diverse antineoplastic regimens, encompassing not only a large panel of immunotherapeutic strategies but also conventional cytotoxic molecules, targeted anticancer agents and irradiation. In line with this notion, several approaches have been devised to elicit novel or boost existing anticancer immune responses, including the administration of immunomodulatory cytokines. Such a relatively unspecific intervention suffices to mediate clinical effects in (at least a subset of) patients bearing particularly immunogenic tumors, like melanoma and renal cell carcinoma. More often, however, immunostimulatory cytokines are administered to boost the immunogenic potential of other agents, including (but not limited to) immune checkpoint-blocking antibodies, anticancer vaccines, oncolytic viruses and immunogenic chemotherapeutics. Here, we summarize the latest advances in the clinical development of recombinant cytokines as an immunomodulatory intervention for cancer therapy. PMID:25083328

  16. Arctic Watch

    NASA Astrophysics Data System (ADS)

    Orcutt, John; Baggeroer, Arthur; Mikhalevsky, Peter; Munk, Walter; Sagen, Hanne; Vernon, Frank; Worcester, Peter

    2015-04-01

    The dramatic reduction of sea ice in the Arctic Ocean will increase human activities in the coming years. This will be driven by increased demand for energy and the marine resources of an Arctic Ocean more accessible to ships. Oil and gas exploration, fisheries, mineral extraction, marine transportation, research and development, tourism and search and rescue will increase the pressure on the vulnerable Arctic environment. Synoptic in-situ year-round observational technologies are needed to monitor and forecast changes in the Arctic atmosphere-ice-ocean system at daily, seasonal, annual and decadal scales to inform and enable sustainable development and enforcement of international Arctic agreements and treaties, while protecting this critical environment. This paper will discuss multipurpose acoustic networks, including subsea cable components, in the Arctic. These networks provide communication, power, underwater and under-ice navigation, passive monitoring of ambient sound (ice, seismic, biologic and anthropogenic), and acoustic remote sensing (tomography and thermometry), supporting and complementing data collection from platforms, moorings and autonomous vehicles. This paper supports the development and implementation of regional to basin-wide acoustic networks as an integral component of a multidisciplinary, in situ Arctic Ocean Observatory.

  17. Watch It

    ERIC Educational Resources Information Center

    Bolch, Matt

    2008-01-01

    For the school chief information officer (CIO), safeguarding students and facilities is as much a part of the job description as keeping the data networks running and the servers protected from hackers. This article describes how two districts, Miami-Dade County Public Schools and Taos Municipal Schools, secured their surveillance systems. The…

  18. Trial Watch

    PubMed Central

    Bloy, Norma; Pol, Jonathan; Manic, Gwenola; Vitale, Ilio; Eggermont, Alexander; Galon, Jérôme; Tartour, Eric; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    During the past two decades, it has become increasingly clear that the antineoplastic effects of radiation therapy do not simply reflect the ability of X-, ?- and ?-rays to damage transformed cells and directly cause their permanent proliferative arrest or demise, but also involve cancer cell-extrinsic mechanisms. Indeed, among other activities, radiotherapy has been shown to favor the establishment of tumor-specific immune responses that operate systemically, underpinning the so-called ‘out-of-field’ or ‘abscopal’ effect. Thus, ionizing rays appear to elicit immunogenic cell death, a functionally peculiar variant of apoptosis associated with the emission of a particularly immunostimulatory combination of damage-associated molecular patterns. In line with this notion, radiation therapy fosters, and thus exacerbates, the antineoplastic effects of various treatment modalities, including surgery, chemotherapy and various immunotherapeutic agents. Here, we summarize recent advances in the use of ionizing rays as a means to induce or potentiate therapeutically relevant anticancer immune responses. In addition, we present clinical trials initiated during the past 12 months to test the actual benefit of radioimmunotherapy in cancer patients. PMID:25941606

  19. Trial Watch

    PubMed Central

    Semeraro, Michaela; Vacchelli, Erika; Eggermont, Alexander; Galon, Jerome; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2013-01-01

    Lenalidomide is a synthetic derivative of thalidomide currently approved by the US Food and Drug Administration for use in patients affected by multiple myeloma (in combination with dexamethasone) and low or intermediate-1 risk myelodysplastic syndromes that harbor 5q cytogenetic abnormalities. For illustrative purposes, the mechanism of action of lenalidomide can be subdivided into a cancer cell-intrinsic, a stromal, and an immunological component. Indeed, lenalidomide not only exerts direct cell cycle-arresting and pro-apoptotic effects on malignant cells, but also interferes with their physical and functional interaction with the tumor microenvironment and mediates a robust, pleiotropic immunostimulatory activity. In particular, lenalidomide has been shown to stimulate the cytotoxic functions of T lymphocytes and natural killer cells, to limit the immunosuppressive impact of regulatory T cells, and to modulate the secretion of a wide range of cytokines, including tumor necrosis factor ?, interferon ? as well as interleukin (IL)-6, IL-10, and IL-12. Throughout the last decade, the antineoplastic and immunostimulatory potential of lenalidomide has been investigated in patients affected by a wide variety of hematological and solid malignancies. Here, we discuss the results of these studies and review the status of clinical trials currently assessing the safety and efficacy of this potent immunomodulatory drug in oncological indications. PMID:24482747

  20. Suicide Watch.

    ERIC Educational Resources Information Center

    Jones, Rebecca

    2001-01-01

    Researchers say the best way to prevent suicide is to find and treat kids with depression and substance-abuse problems. Schools should also develop a suicide-prevention policy, make curriculum decisions wisely, train staff as detectives, notify parents, make sure affected children get help, and attend to survivors. (Contains 13 references.) (MLH)

  1. Trial Watch:

    PubMed Central

    Pol, Jonathan; Bloy, Norma; Obrist, Florine; Eggermont, Alexander; Galon, Jérôme; Cremer, Isabelle; Erbs, Philippe; Limacher, Jean-Marc; Preville, Xavier; Zitvogel, Laurence; Kroemer, Guido; Galluzzi, Lorenzo

    2014-01-01

    Oncolytic viruses are natural or genetically modified viral species that selectively infect and kill neoplastic cells. Such an innate or exogenously conferred specificity has generated considerable interest around the possibility to employ oncolytic viruses as highly targeted agents that would mediate cancer cell-autonomous anticancer effects. Accumulating evidence, however, suggests that the therapeutic potential of oncolytic virotherapy is not a simple consequence of the cytopathic effect, but strongly relies on the induction of an endogenous immune response against transformed cells. In line with this notion, superior anticancer effects are being observed when oncolytic viruses are engineered to express (or co-administered with) immunostimulatory molecules. Although multiple studies have shown that oncolytic viruses are well tolerated by cancer patients, the full-blown therapeutic potential of oncolytic virotherapy, especially when implemented in the absence of immunostimulatory interventions, remains unclear. Here, we cover the latest advances in this active area of translational investigation, summarizing high-impact studies that have been published during the last 12 months and discussing clinical trials that have been initiated in the same period to assess the therapeutic potential of oncolytic virotherapy in oncological indications. PMID:25097804

  2. A programmable image compression system

    NASA Technical Reports Server (NTRS)

    Farrelle, Paul M.

    1989-01-01

    A programmable image compression system which has the necessary flexibility to address diverse imaging needs is described. It can compress and expand single frame video images (monochrome or color) as well as documents and graphics (black and white or color) for archival or transmission applications. Through software control, the compression mode can be set for lossless or controlled quality coding; the image size and bit depth can be varied; and the image source and destination devices can be readily changed. Despite the large combination of image data types, image sources, and algorithms, the system provides a simple consistent interface to the programmer. This system (OPTIPAC) is based on the TITMS320C25 digital signal processing (DSP) chip and has been implemented as a co-processor board for an IBM PC-AT compatible computer. The underlying philosophy can readily be applied to different hardware platforms. By using multiple DSP chips or incorporating algorithm specific chips, the compression and expansion times can be significantly reduced to meet performance requirements.

  3. GMES Space Component: Programme overview

    NASA Astrophysics Data System (ADS)

    Aschbacher, J.; Milagro-Perez, M. P.

    2012-04-01

    The European Union (EU) and the European Space Agency (ESA) have developed the Global Monitoring for Environment and Security (GMES) programme as Europe's answer to the vital need for joined-up data about our climate, environment and security. Through a unique combination of satellite, atmospheric and Earth-based monitoring systems, the initiative will provide new insight into the state of the land, sea and air, providing policymakers, scientists, businesses and the public with accurate and timely information. GMES capabilities include monitoring and forecasting of climatic change, flood risks, soil and coastal erosion, crop and fish resources, air pollution, greenhouse gases, iceberg distribution and snow cover, among others. To accomplish this, GMES has been divided into three main components: Space, In-situ and Services. The Space Component, led by ESA, comprises five types of new satellites called Sentinels that are being developed by ESA specifically to meet the needs of GMES, the first of which to be launched in 2013. These missions carry a range of technologies, such as radar and multi-spectral imaging instruments for land, ocean and atmospheric monitoring. In addition, access to data from the so-called Contributing Missions guarantees that European space infrastructure is fully used for GMES. An integrated Ground Segment ensures access to Sentinels and Contributing Missions data. The in-situ component, under the coordination of the European Environment Agency (EEA), is composed of atmospheric and Earth based monitoring systems, and based on established networks and programmes at European and international levels. The European Commission is in charge of implementing the services component of GMES and of leading GMES overall. GMES services, fed with data from the Space and In-situ components, will provide essential information in five main domains, atmosphere, ocean and land monitoring as well as emergency response and security. Climate change has been added as a new GMES service and cross-cuts all these domains. Even if GMES is built to primarily serve operational services, there is a large benefit for science users as well. In addition, science will be crucial to advance services and provide critical input to the definition of new observation systems. Access to Sentinel data is governed by the Sentinel data policy, which is part of a wider GMES data and information access policy. The Sentinel data policy envisages free and open access, subject to restrictions only if security or other European interests need to be preserved. The programme will enter the operational phase in 2014, when the first dedicated spacecraft, the Sentinel missions, will be in orbit. The main programmatic challenge is to ensure the programme's long-term sustainability. This session aims at informing users about the current programme's overall status and its potential for users in the services and scientific fields.

  4. The European eLearning Programme(s): Between Rhetoric and Reality

    ERIC Educational Resources Information Center

    Salajan, Florin D.

    2007-01-01

    This article presents the findings of a qualitative study conducted by the author on the implications of e-learning programmes for the higher education systems of the member states of the European Union. The study takes a look behind the scenes of the eLearning Programme and other e-learning actions within other European programmes by tapping into…

  5. Programme Theory, Programme Documents and State Standards in Evaluating Teacher Education

    ERIC Educational Resources Information Center

    Papanastasiou, Elena C.; Tatto, Maria Teresa; Neophytou, Lefkios

    2012-01-01

    Across the USA as well as worldwide, numerous universities offer teacher preparation programmes and award such degrees. However, there are no consistent valid or reliable indicators for determining the coherence and quality of these programmes. An effective way of starting to evaluate these programmes is by looking at their standards and their…

  6. Experimental study of the differential effects of playing versus watching violent video games on children's aggressive behavior.

    PubMed

    Polman, Hanneke; de Castro, Bram Orobio; van Aken, Marcel A G

    2008-01-01

    There is great concern about the effects of playing violent video games on aggressive behavior. The present experimental study was aimed at investigating the differential effects of actively playing vs. passively watching the same violent video game on subsequent aggressive behavior. Fifty-seven children aged 10-13 either played a violent video game (active violent condition), watched the same violent video game (passive violent condition), or played a non-violent video game (active non-violent condition). Aggression was measured through peer nominations of real-life aggressive incidents during a free play session at school. After the active participation of actually playing the violent video game, boys behaved more aggressively than did the boys in the passive game condition. For girls, game condition was not related to aggression. These findings indicate that, specifically for boys, playing a violent video game should lead to more aggression than watching television violence. PMID:18161877

  7. Geostatistical Analyses of Interactions between Minke Whales (Balaenoptera acutorostrata) and Whale-Watching Boats in Skjalfandi Bay, Northeast Iceland

    NASA Astrophysics Data System (ADS)

    Cummings, Joshua I.

    The Icelandic whale-watching industry has experienced rapid growth since its inception in 1991, and today represents the fastest growing economic activity of the country. Skjalfandi Bay in Northeast Iceland has become the epicenter of whale-watching in Iceland, yet little is known about the local effects of the whale-watching industry on cetaceans. I used theodolite techniques and GIS to examine boat effects on the swimming speed, directionality, inter-breath intervals, and surface feeding events of minke whales (Balaenoptera acutorostrata) in Skjalfandi Bay. The proximity and number of vessels did not have a statistically significant effect on any aspect of minke behavior. These results contradict a previous study from Faxafloi Bay, suggesting that differences exist between the two locations, and that management strategies may need to be location-specific.

  8. Part Two: Learning Science Through Digital Video: Student Views on Watching and Creating Videos

    NASA Astrophysics Data System (ADS)

    Wade, P.; Courtney, A. R.

    2014-12-01

    The use of digital video for science education has become common with the wide availability of video imagery. This study continues research into aspects of using digital video as a primary teaching tool to enhance student learning in undergraduate science courses. Two survey instruments were administered to undergraduate non-science majors. Survey One focused on: a) What science is being learned from watching science videos such as a "YouTube" clip of a volcanic eruption or an informational video on geologic time and b) What are student preferences with regard to their learning (e.g. using video versus traditional modes of delivery)? Survey Two addressed students' perspectives on the storytelling aspect of the video with respect to: a) sustaining interest, b) providing science information, c) style of video and d) quality of the video. Undergraduate non-science majors were the primary focus group in this study. Students were asked to view video segments and respond to a survey focused on what they learned from the segments. The storytelling aspect of each video was also addressed by students. Students watched 15-20 shorter (3-15 minute science videos) created within the last four years. Initial results of this research support that shorter video segments were preferred and the storytelling quality of each video related to student learning.

  9. Waterway wide area tactical coverage and homing (WaterWATCH) program overview

    NASA Astrophysics Data System (ADS)

    Driggers, Gerald; Cleveland, Tammy; Araujo, Lisa; Spohr, Robert; Umansky, Mark

    2008-04-01

    The Congressional and Army sponsored WaterWATCH TM Program has developed and demonstrated a fully integrated shallow water port and facility monitoring system. It provides fully automated monitoring of domains above and below the surface of the water using primarily off-the-shelf sensors and software. The system is modular, open architecture and IP based, and elements can be mixed and matched to adapt to specific applications. The sensors integrated into the WaterWATCH TM system include cameras, radar, passive and active sonar, and various motion detectors. The sensors were chosen based on extensive requirements analyses and tradeoffs. Descriptions of the system and individual sensors are provided, along with data from modular and system level testing. Camera test results address capabilities and limitations associated with using "smart" image analysis software with stressing environmental issues such as bugs, darkness, rain and snow. Radar issues addressed include achieving range and resolution requirements. The passive sonar capability to provide near 100% true positives with zero false positives is demonstrated. Testing results are also presented to show that inexpensive active sonar can be effective against divers with or without SCUBA gear and that false alarms due to fish can be minimized. A simple operator interface has also been demonstrated.

  10. Degree Entry Programme Engineering / Key details

    E-print Network

    Painter, Kevin

    Degree Entry Programme Engineering / Computing Key details Duration: 2 semesters (full-time) Delivery type: Day Intake date: September, January Fees: 38000 AED Overview This programme is designed to provide students with a pathway into an undergraduate degree in Engineering or Computing at the Dubai

  11. Handwashing Programme in Kindergarten: A Pilot Study

    ERIC Educational Resources Information Center

    Au, W. H.; Suen, L. K. P.; Kwok, Y. L.

    2010-01-01

    Purpose: The purpose of this paper is to evaluate the effectiveness of a structured programme on handwashing which has taken into account of the developmental stage of children. Design/methodology/approach: This is a pilot study using a structured handwashing programme as intervention. The intervention group (n=15) receives the structured…

  12. Erasmus + Programme Erasmus Policy Statement (Overall Strategy)

    E-print Network

    Di Pillo, Gianni

    the Erasmus placement and Leonardo da Vinci programme. For Erasmus placements, the choice of the organization is often made by the Faculties whether for the Leonardo da Vinci we use a centralized approach. The Leonardo da Vinci programme UNIPHARMA-GRADUTES coordinated by Sapienza was shortlisted in 2006

  13. Gender Differences in Peace Education Programmes

    ERIC Educational Resources Information Center

    Yablon, Yaacov Boaz

    2009-01-01

    Peace education programmes have become part of the school curriculum all over the world, as a way to enhance positive relationships between conflict groups. However, although gender differences are being taken into account when planning various educational programmes, this is usually not the case with peace education. The present study aimed to…

  14. Tuition Fees 2014-15 Undergraduate Programmes

    E-print Network

    Chittka, Lars

    Tuition Fees 2014-15 Undergraduate Programmes New students: Page Pre-sessional English language in Oral Health Education (part-time) £825 £2,175 Y2GE International Foundation Programme in Humanities Business Management £9,000 £13,750 L100 BSc (Econ) Economics £9,000 £13,500 LG11 BSc (Econ) Economics

  15. MSc Integrated Petroleum Geoscience Programme Handbook

    E-print Network

    Neri, Peter

    MSc Integrated Petroleum Geoscience Programme Handbook 2013-14 edition #12;Page 2 Contents Preface 3 1.MSc Integrated Petroleum Geoscience ­ FAQ 4 1.1 Why should I do this programme? 4 1.2 What Integrated Petroleum Geoscience: 57F610B1 PgDip Integrated Petroleum Geoscience: 61F610VX PgCert Integrated

  16. PROGRAMME GROUP RESEARCH UPDATE: Rural & urban landscape

    E-print Network

    1 PROGRAMME GROUP RESEARCH UPDATE: Rural & urban landscape ecology programme group Introduction Kevin Watts The purpose of the rural and urban landscape ecology group (ruLE) is to conduct and manage agendas (including habitat networks and urban greening). In this issue we highlight work on four current

  17. Cardiff School of Psychology Undergraduate Degree Programmes

    E-print Network

    Martin, Ralph R.

    School of Psychology OUTSTANDING FACILITIES BRIGHT PROSPECTS WORLD-CLASS RESEARCH AWARDCardiff School of Psychology Undergraduate Degree Programmes www.cardiff.ac.uk/psych #12;Cardiff in Cardiff 8 Student Life 9 Cardiff School of Psychology 10 Undergraduate Degree Programmes 13 Degree

  18. Evaluating Large-Scale Interactive Radio Programmes

    ERIC Educational Resources Information Center

    Potter, Charles; Naidoo, Gordon

    2009-01-01

    This article focuses on the challenges involved in conducting evaluations of interactive radio programmes in South Africa with large numbers of schools, teachers, and learners. It focuses on the role such large-scale evaluation has played during the South African radio learning programme's development stage, as well as during its subsequent…

  19. Erasmus Mundus SEN: The Inclusive Scholarship Programme?

    ERIC Educational Resources Information Center

    Grinbergs, Christopher J.; Jones, Hilary

    2013-01-01

    The Erasmus Mundus MA/Mgr in Special Education Needs (EM SEN) was created as a Masters Course funded by the European Commission's Erasmus Mundus Programme (EMP) to challenge and educate students in inclusive policy and practice in education. Yet, it is debatable the extent to which this programme embodies the values of an inclusive approach,…

  20. HORIZON 2020 WORK PROGRAMME 2016 2017

    E-print Network

    Hasýrcý, Vasýf

    HORIZON 2020 WORK PROGRAMME 2016 ­ 2017 DRAFT 3. Marie Sklodowska-Curie Actions #12;HORIZON 2020 ­ WORK PROGRAMME 2016-2017 Marie Sklodowska-Curie Actions Part 3 - Page 2 of 40 Table of contents................................................................................................................................ 3 2016 Call for Marie Sklodowska-Curie Innovative Training Networks (ITN

  1. Students' Perception of Industrial Internship Programme

    ERIC Educational Resources Information Center

    Renganathan, Sumathi; Karim, Zainal Ambri Bin Abdul; Li, Chong Su

    2012-01-01

    Purpose: An important aspect of an academic curriculum in higher learning institutions for technical disciplines is the industrial internship programme for students. The purpose of this paper is to investigate students' perception of the effectiveness of an industrial internship programme offered by a private technological university in Malaysia.…

  2. COMPARATIVE RESEARCH PROGRAMME ON POVERTY Internships

    E-print Network

    Maróti, Miklós

    COMPARATIVE RESEARCH PROGRAMME ON POVERTY Internships The Comparative Research Programme on Poverty. Internships at CROP are currently only open to students seeking academic credit at their university through editing carrying out general administrative tasks Terms and conditions Internships can be arranged

  3. An overview of the STFC Futures Programme

    E-print Network

    of the Futures Programme Brayn Edwards Defence, Security and Resilience Theme Leader Kevin Smith Energy societal challenges: 1. Energy 2. Environment 3. Healthcare 4. Security Challenge-led programme Creates at broadening STFC impact in energy, environment, healthcare and security The STFC Futures Health and Cancer

  4. Admissions statement for Orthodontics (DDS) Programmes covered

    E-print Network

    Bristol, University of

    Admissions statement for Orthodontics (DDS) Programmes covered This admissions statement relates to the following programme: Orthodontics (DDS). Applicants should also refer to the relevant prospectus entry. The next intake for Orthodontics (DDS) will be in 2017. The application process for UK and EU students

  5. THE UNIVERSITY OF MANCHESTER Undergraduate Programme Specification

    E-print Network

    Sidorov, Nikita

    -time (exit award only) Certificate Mathematics with Business and Management 1 year Full time (exit award onlyTHE UNIVERSITY OF MANCHESTER Undergraduate Programme Specification Programme Specification: Mathematics with Business and Management Last printed 12/20/2013 11:33:00 AM 1 Mathematics with Business

  6. Director's Foreword Brief Scientific Report on Programmes

    E-print Network

    scientific achievement at the Isaac Newton Institute. The pages that follow record the programmes that have Programmes National Advisory Board and UK Mathematics Newton Institute Correspondents Other Institute News the Institute on request, or from http://www.newton.cam.ac.uk/reports/0405/appendices.html 1 Long

  7. Aurora europe's space exploration programme

    NASA Astrophysics Data System (ADS)

    Ongaro, F.; Swings, J. P.; Condessa, R.

    2003-04-01

    What will happen after the ISS in terms of space exploration, specifically to the human presence beyond Earth? What will be the role of Europe in the future international venture to explore space? What are the most immediate actions to be undertaken in Europe in order to best profit from the efforts made through the participation in the ISS and to position Europe's capabilities according to its interests? As approved by the Ministers at the Edinburgh Council in November 2001, the European Space Exploration Programme - Aurora - is ESA's programme in charge of defining and implementing the long term plan for human and robotic exploration of the Solar system. The Aurora programme started in 2002 and extends until the end goal of Aurora: the first human mission to Mars, expected in the 2025-2030 time-frame. The approach of Aurora is to implement a robust development of technologies and robotic missions, in parallel to the utilization phase of the ISS, to prepare for a continuous and sustainable future of human space exploration (which shall include the Moon, Mars and the asteroids as targets), in which Europe will be a valuable partner. Two classes of missions are foreseen in the programme's strategy: Flagships, defined as major missions driving to soft landing, in-situ analysis, sample return from other planetary bodies and eventually human missions; and Arrows, defined as cost-capped, short development time missions to demonstrate new technologies or mission approaches, or to exploit opportunities for payloads on European or international missions. So far the participating national delegations have approved two Flagships (ExoMars and Mars Sample Return) and two Arrows (Earth Re-entry and Mars Aerocapture) for phase A industrial studies. Although the last call for ideas of Aurora resulted in the definition of two Flagship missions targeted to Mars, the next one might be aimed to the Moon. At this stage the role of the Moon, on the path of Mars exploration is not totally clear, however in the Aurora long term plan a lander mission is being considered for the first half of the next decade and a human mission for later on. An example of what an Arrow mission to the Moon could be is SMART-1, in this class a cooperative opportunity for lunar exploration could be envisaged. ExoMars is proposed to fly in 2009 and is an exobiology driven mission. It includes a rover carrying a payload called Pasteur, which integrates a set of instruments with the primary objective of identifying biosignatures. A secondary objective is to assess the hazards (e.g. radiation) to human exploration. Mars Sample Return, aimed for launch in 2011, is one of the most important milestones for Mars exploration as even a small amount of sample brought back to Earth will dramatically increase our knowledge about the red planet. Besides, this would be the first mission to incorporate all the basic operations of a human mission. Earth Re-entry will validate technologies required for future missions, namely the Mars Sample Return. Mars Aerocapture will test an orbit insertion technique, which could significantly reduce the cost of future missions. The assessment of priorities and most urgent technology fields to be developed by Europe, within an international framework, are determined taking into consideration the technologies that will enable the most immediate Aurora missions; as well those which are fundamental for the European interests and need an early development start given their complexity or originality. Fields which will be of relevance to planetary exploration include: Automated guidance & navigation control; Micro-Avionics; Data Processing & Communication Entry, Descent and Landing; Crew and Life Support Systems; In Situ Resource Utilisation; Power generation, conditioning and storage; Propulsion (In-space transportation, Ascent/descent vehicles); Robotics and mechanisms; Structure & thermal control; Instrument Technologies.

  8. Field Evaluation of Programmable Thermostats

    SciTech Connect

    Sachs, O.; Tiefenbeck, V.; Duvier, C.; Qin, A.; Cheney, K.; Akers, C.; Roth, K.

    2012-12-01

    Prior research suggests that poor programmable thermostats usability may prevent their effective use to save energy. We hypothesized that home occupants with a high-usability thermostats would be more likely to use them to save energy than people with a basic thermostat. We randomly installed a high-usability thermostat in half the 77 apartments of an affordable housing complex, installing a basic thermostat in the other half. During the heating season, we collected space temperature and furnace on-off data to evaluate occupant interaction with the thermostats, foremost nighttime setbacks. We found that thermostat usability did not influence energy-saving behaviors, finding no significant difference in temperature maintained among apartments with high- and low-usability thermostats.

  9. The Scientific Return of VLT Programmes

    NASA Astrophysics Data System (ADS)

    Sterzik, M.; Dumas, C.; Grothkopf, U.; Kaufer, A.; Leibundgut, B.; Marteau, S.; Meakins, S.; Patat, F.; Primas, F.; Rejkuba, M.; Romaniello, M.; Stoehr, F.; Tacconi-Garman, L.; Vera, I.

    2015-12-01

    An in-depth analysis of the publications from 8414 distinct scheduled VLT observing programmes between April 1999 and March 2015 (Periods 63 to 94) is presented. The productivity by mode (Visitor or Service Mode) and type (Normal and Large, Guaranteed Time, Target of Opportunity, Director’s Discretionary Time) are examined through their publication records. We investigate how Service Mode rank classes impact the scientific return. Several results derive from this study: Large Programmes result in the highest productivity, whereas only about half of all scheduled observing programmes produce a refereed publication. Programmes that result in a publication yield on average two refereed papers. B rank class Service Mode Programmes appear to be slightly less productive. Follow-up studies will investigate in more detail the parameters that influence the productivity of the Observatory.

  10. XML does Real Programmers a Service

    SciTech Connect

    Gorton, Ian

    2008-09-01

    As the sun slowly sets of this first decade of the new millenium, it seems appropriate to update the sojourn of the real programmers as they adapt to their ever changing technical and business environment. Real Programmers were perfectly characterized and differentiated from their quiche-eating, Pascal programming brethren in Ed Post’s seminal “Real Programmers Don’t Use Pascal” (Datamation, 1983). My follow-up ("Real programmers do use Delphi," Software, IEEE , vol.12, no.6, pp.8, 10, 12-, Nov 1995) charted their evolution from FORTRAN-only programmers to embracing a wider range of mainstream languages and tools that still afforded ample opportunity for creativity, game-playing, irregular work hours, and importantly, long-term job security.

  11. Sheridan, S.C. and L.S. Kalkstein, 1998: Health watch/warning systems in urban areas. World Resource Review, 10, 375-383.

    E-print Network

    Sheridan, Scott

    to the body when temperatures are excessive (Steadman 1979). Many watch-warning systems account for neither1 Sheridan, S.C. and L.S. Kalkstein, 1998: Health watch/warning systems in urban areas. World Resource Review, 10, 375-383. INTRODUCTION Interest in the impact of weather on human health has increased

  12. 76 FR 4284 - Foreign-Trade Zone 49-Newark, NJ Area; Application for Subzone; LVMH Watch & Jewelry U.S.A., Inc...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... Foreign-Trade Zones Board Foreign-Trade Zone 49--Newark, NJ Area; Application for Subzone; LVMH Watch... LVMH Watch & Jewelry U.S.A., Inc. (LVMH), located in Springfield, New Jersey. The application was... regulations of the Board (15 CFR part 400). It was formally filed on January 14, 2011. The LVMH facility...

  13. 21 CFR 870.1425 - Programmable diagnostic computer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...2011-04-01 false Programmable diagnostic computer. 870.1425 Section 870.1425...870.1425 Programmable diagnostic computer. (a) Identification. A programmable diagnostic computer is a device that can be...

  14. 21 CFR 870.1425 - Programmable diagnostic computer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...2012-04-01 false Programmable diagnostic computer. 870.1425 Section 870.1425...870.1425 Programmable diagnostic computer. (a) Identification. A programmable diagnostic computer is a device that can be...

  15. 21 CFR 870.1425 - Programmable diagnostic computer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...2010-04-01 false Programmable diagnostic computer. 870.1425 Section 870.1425...870.1425 Programmable diagnostic computer. (a) Identification. A programmable diagnostic computer is a device that can be...

  16. 21 CFR 870.1425 - Programmable diagnostic computer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...2014-04-01 false Programmable diagnostic computer. 870.1425 Section 870.1425...870.1425 Programmable diagnostic computer. (a) Identification. A programmable diagnostic computer is a device that can be...

  17. 21 CFR 870.1425 - Programmable diagnostic computer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...2013-04-01 false Programmable diagnostic computer. 870.1425 Section 870.1425...870.1425 Programmable diagnostic computer. (a) Identification. A programmable diagnostic computer is a device that can be...

  18. 21 CFR 870.1750 - External programmable pacemaker pulse generator.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...External programmable pacemaker pulse generator. 870.1750 Section 870.1750...External programmable pacemaker pulse generator. (a) Identification. An external programmable pacemaker pulse generators is a device that can be...

  19. 21 CFR 870.1750 - External programmable pacemaker pulse generator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...External programmable pacemaker pulse generator. 870.1750 Section 870.1750...External programmable pacemaker pulse generator. (a) Identification. An external programmable pacemaker pulse generators is a device that can be...

  20. 21 CFR 870.1750 - External programmable pacemaker pulse generator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...External programmable pacemaker pulse generator. 870.1750 Section 870.1750...External programmable pacemaker pulse generator. (a) Identification. An external programmable pacemaker pulse generators is a device that can be...

  1. 21 CFR 870.1750 - External programmable pacemaker pulse generator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...External programmable pacemaker pulse generator. 870.1750 Section 870.1750...External programmable pacemaker pulse generator. (a) Identification. An external programmable pacemaker pulse generators is a device that can be...

  2. 21 CFR 870.1750 - External programmable pacemaker pulse generator.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...External programmable pacemaker pulse generator. 870.1750 Section 870.1750...External programmable pacemaker pulse generator. (a) Identification. An external programmable pacemaker pulse generators is a device that can be...

  3. Graz University of Technology Curriculum for the University Graduate Programme

    E-print Network

    Ganster, Maximilian

    technicians, road engineers, etc.). Graduate programme organisation § 2 Duration and structure (1 Programme objective § 2 Duration and structure § 3 Academic direction and Programme administration § 4 Vehicle development Safety engineering Road engineering Vehicle engineering The university graduate

  4. The role of intergenerational influence in waste education programmes: the THAW project.

    PubMed

    Maddox, P; Doran, C; Williams, I D; Kus, M

    2011-12-01

    Whilst the education of young people is often seen as a part of the solution to current environmental problems seeking urgent attention, it is often forgotten that their parents and other household members can also be educated/influenced via home-based educational activities. This paper explores the theory of intergenerational influence in relation to school based waste education. Waste Watch, a UK-based environmental charity (www.wastewatch.org.uk), has pioneered a model that uses practical activities and whole school involvement to promote school based action on waste. This methodology has been adopted nationally. This paper outlines and evaluates how effective school based waste education is in promoting action at a household level. The paper outlines Waste Watch's 'Taking Home Action on Waste (THAW)' project carried out for two and half years in Rotherham, a town in South Yorkshire, England. The project worked with 6705 primary age children in 39 schools (44% of primary schools in the project area) to enable them to take the "reduce, reuse and recycle message" home to their families and to engage these (i.e. families) in sustainable waste management practices. As well as substantial increases in students' knowledge and understanding of waste reduction, measurement of the impact of the project in areas around 12 carefully chosen sample schools showed evidence of increased participation in recycling and recycling tonnages as well as declining levels of residual waste. Following delivery of the project in these areas, an average increase of 8.6% was recorded in recycling set out rates which led to a 4.3% increase in paper recycling tonnages and an 8.7% increase in tonnages of cans, glass and textiles collected for recycling. Correspondingly, there was a 4.5% fall in tonnages of residual waste. Waste Watch's THAW project was the first serious attempt to measure the intergenerational influence of an education programme on behaviour at home (i.e. other than schools' own waste). It clearly shows that household recycling behaviour can be positively impacted by intergenerational influence via a practical school-based waste education model. However, although the model could potentially have a big impact if rolled out nationally, it will require seed funding and the long-term durability of the model has not yet been fully quantified. PMID:21868211

  5. Programmer`s manual for CAMCON: Compliance Assessment Methodology CONtroller

    SciTech Connect

    Rechard, R.P.; Gilkey, A.P.; Rudeen, D.K.; Byle, K.A.; Iuzzolino, H.J.

    1993-05-01

    CAMCON, the Compliance Assessment Methodology CONtroller, is an analysis system that assists in assessing the compliance of the Waste Isolation Pilot Plant (WIPP) with applicable long-term regulations of the US Environmental Protection Agency, including Subpart B of the Environmental Standards for the Management and Disposal of spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes, 40 CFR 191 and 40CFR268.6, which is the portion of the Land Disposal Restrictions implementing the Resource, Conservative, and Recovery Act of 1976, as amended that states the conditions for disposal of hazardous chemical wastes. This manual provides an architectural overview of the CAMCON system. Furthermore this manual presents guidelines and presents suggestions for programmers developing the many different types of software necessary to investigate various events and physical processes of the WIPP. These guidelines include user interface requirements, minimum quality assurance requirements, coding style suggestions, and the use of numerous software libraries developed specifically for or adapted for the CAMCON system.

  6. National and regional asthma programmes in Europe.

    PubMed

    Selroos, Olof; Kupczyk, Maciej; Kuna, Piotr; ?acwik, Piotr; Bousquet, Jean; Brennan, David; Palkonen, Susanna; Contreras, Javier; FitzGerald, Mark; Hedlin, Gunilla; Johnston, Sebastian L; Louis, Renaud; Metcalf, Leanne; Walker, Samantha; Moreno-Galdó, Antonio; Papadopoulos, Nikolaos G; Rosado-Pinto, José; Powell, Pippa; Haahtela, Tari

    2015-09-01

    This review presents seven national asthma programmes to support the European Asthma Research and Innovation Partnership in developing strategies to reduce asthma mortality and morbidity across Europe. From published data it appears that in order to influence asthma care, national/regional asthma programmes are more effective than conventional treatment guidelines. An asthma programme should start with the universal commitments of stakeholders at all levels and the programme has to be endorsed by political and governmental bodies. When the national problems have been identified, the goals of the programme have to be clearly defined with measures to evaluate progress. An action plan has to be developed, including defined re-allocation of patients and existing resources, if necessary, between primary care and specialised healthcare units or hospital centres. Patients should be involved in guided self-management education and structured follow-up in relation to disease severity. The three evaluated programmes show that, thanks to rigorous efforts, it is possible to improve patients' quality of life and reduce hospitalisation, asthma mortality, sick leave and disability pensions. The direct and indirect costs, both for the individual patient and for society, can be significantly reduced. The results can form the basis for development of further programme activities in Europe. PMID:26324809

  7. Children's Hostile Attribution Bias Is Reduced after Watching Realistic Playful Fighting, and the Effect Is Mediated by Prosocial Thoughts

    ERIC Educational Resources Information Center

    Boulton, Michael J.

    2012-01-01

    Hostile attribution bias (HAB) has been found to characterize aggressive children. Watching prosocial media has been shown to have positive effects on children, and the general learning model has been used to account for these observations. This study tested the hypotheses derived from this theory that exposure to playful fighting would lead to a…

  8. 46 CFR 11.329 - Requirements to qualify for an STCW endorsement as Officer in Charge of an Engineering Watch...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Requirements to qualify for an STCW endorsement as Officer in Charge of an Engineering Watch (OICEW) in a manned engineroom or designated duty engineer in a periodically unmanned engineroom on vessels powered by main propulsion machinery of 750 kW/1,000 HP propulsion power or more (operational...

  9. Relationship between Noctcaelador and Aesthetic Sensitivity: Art-Related Personality Factors Associated with College Students' Night-Sky Watching

    ERIC Educational Resources Information Center

    Kelly, William E.

    2008-01-01

    This study explored the relationship between positive attitudes and behaviors concerning night-sky watching (noctcaelador) and aesthetic sensitivity. College students (N = 106) completed the Noctcaelador Inventory (Kelly, 2004a) and a shortened version of the Sensitivity Questionnaire (Child, 1965). Noctcaelador was significantly, positively…

  10. Pick a Hand, Any Hand: Mixed-Handedness and Night-Sky Watching in a College Student Sample

    ERIC Educational Resources Information Center

    Kelly, William E.

    2009-01-01

    This study explored the relationship between handedness and interest in night-sky watching. University students (N= 128) completed the Edinburgh Handedness Inventory (Oldfield, 1971) and the Noctcaelador Inventory (Kelly, 2004). The findings indicated that mixed-handed participants scored highest on noctcaelador relative to those classified as…

  11. The New Classified Research. Corporate Sponsored Biomedical Research and the Reign of Secrecy at Harvard University. A Harvard Watch Report.

    ERIC Educational Resources Information Center

    Bourke, Jaron

    Harvard Watch asserts that withholding essential information from public scrutiny is not uncommon at Harvard University. Maintaining that Harvard has reversed its position from extolling the virtues of public disclosure to one of imposing secrecy, the document suggests that this about face is linked to the university's recent collaboration with…

  12. A Need For Correction: Reforming New York's Juvenile Justice System. Child Welfare Watch. Vol. 18, Fall 2009

    ERIC Educational Resources Information Center

    White, Andrew; Hemphill, Clara; Hurley, Kendra

    2009-01-01

    In the wake of a U.S. Justice Department investigation that found widespread use of excessive force by staff at upstate psychiatric care facilities for mentally ill children, this new edition of Child Welfare Watch identifies shortcomings in mental health services and explores possible solutions, including the expansion of alternatives to…

  13. nature methods | VOL.7 NO.1 | JANUARY 2010 | 37 MethOds tO wAtch | special feature

    E-print Network

    Cai, Long

    , live organ- ism with a m i n i m a l genome, as a method to watch. Although that task was notachieved i the code of life are really five. The occurrence of a methyl modification on cytosine has important sequences using a redundant code in which a thymine can represent either a thymine or an unmethylated

  14. Behind the Scenes / Govt closely watching efforts to actively use Arctic 8:59 pm, November 18, 2015

    E-print Network

    Banbara, Mutsunori

    military strength there. The Arctic Ocean is surrounded by five nations, including the United States to sail across the Arctic Ocean. Another factor behind the murky prospects for Arctic regionALL GENRES Behind the Scenes / Govt closely watching efforts to actively use Arctic region #12

  15. WhaleWatch: An Intelligent Multimedia Math Tutor David M. Hart, Ivon Arroyo, Joseph E. Beck and Beverly P. Woolf

    E-print Network

    Massachusetts at Amherst, University of

    with these features in mind, using the study of endangered species such as Right Whales as a context for problem also suggest beneficial tutor modifications that will be incorporated WhaleWatch's successor, Animal and science career fields, a problem that is getting worse instead of better in areas such as Computer Science

  16. 78 FR 44957 - Agency Information Collection Activities: BioWatch Filter Holder Log, Filter Holder Log DHS Form...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... Final Rule; FR citation: 67 FR 76908 and the CDC Interim Final Rule 42 CFR Part 73 Possession, Use, and Transfer of Select Agents and Toxins; Interim Final Rule; FR citation: 67 FR 76886, inter alia. Information... SECURITY Agency Information Collection Activities: BioWatch Filter Holder Log, Filter Holder Log DHS...

  17. Published on Science 2.0 (http://www.science20.com) Home > Life Sciences > Genetics & Molecular Biology > News Articles > Rad51: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Breast Cancer

    E-print Network

    Kowalczykowski, Stephen C.

    Biology > News Articles > Rad51: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Breast Cancer Rad51: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Breast: Watching Single Strands Of DNA Being Prepped For Repair Could Help Fight Br... 6/17/2013http

  18. Data Observations on Double Shell Tank (DST) Flammable Gas Watch List Tank Behavior

    SciTech Connect

    HEDENGREN, D.C.

    2000-09-28

    This report provides the data from the retained gas sampler, void fraction instrument, ball rheometer, standard hydrogen monitoring system, and other tank data pertinent to gas retention and release behavior in the waste stored in double-shelled Flammable Gas Watch List tanks at Hanford. These include tanks 241-AN-103,241-AN-104, 241-AN-105, 241-AW-101, 241-SY-101, and 241-SY-103. The tanks and the waste they contain are described in terms of fill history and chemistry. The results of mixer pump operation and recent waste transfers and back-dilution in SY-101 are also described. In-situ measurement and monitoring systems are described and the data are summarized under the categories of thermal behavior, waste configuration and properties, gas generation and composition, gas retention and historical gas release behavior.

  19. TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

    PubMed

    Demichelis, F; Fall, K; Perner, S; Andrén, O; Schmidt, F; Setlur, S R; Hoshida, Y; Mosquera, J-M; Pawitan, Y; Lee, C; Adami, H-O; Mucci, L A; Kantoff, P W; Andersson, S-O; Chinnaiyan, A M; Johansson, J-E; Rubin, M A

    2007-07-01

    The identification of the TMPRSS2:ERG fusion in prostate cancer suggests that distinct molecular subtypes may define risk for disease progression. In surgical series, TMPRSS2:ERG fusion was identified in 50% of the tumors. Here, we report on a population-based cohort of men with localized prostate cancers followed by expectant (watchful waiting) therapy with 15% (17/111) TMPRSS2:ERG fusion. We identified a statistically significant association between TMPRSS2:ERG fusion and prostate cancer specific death (cumulative incidence ratio=2.7, P<0.01, 95% confidence interval=1.3-5.8). Quantitative reverse-transcription-polymerase chain reaction demonstrated high ets-related [corrected] gene (ERG) expression to be associated with TMPRSS2:ERG fusion (P<0.005). These data suggest that TMPRSS2:ERG fusion prostate cancers may have a more aggressive phenotype, possibly mediated through increased ERG expression. PMID:17237811

  20. Listening, Watching, and Reading: The Structure and Correlates of Entertainment Preferences

    PubMed Central

    Rentfrow, Peter J.; Goldberg, Lewis R.; Zilca, Ran

    2010-01-01

    People spend considerable amounts of time and money listening to music, watching TV and movies, and reading books and magazines, yet almost no attention in psychology has been devoted to understanding individual differences in preferences for such entertainment. The present research was designed to examine the structure and correlates of entertainment genre preferences. Analyses of the genre preferences of over 3,000 individuals revealed a remarkably clear factor structure. Using multiple samples, methods, and geographic regions, data converged to reveal five entertainment-preference dimensions: Communal, Aesthetic, Dark, Thrilling, and Cerebral. Preferences for these entertainment dimensions were uniquely related to demographics and personality traits. Results also indicated that personality accounted for significant proportions of variance in entertainment preferences over and above demographics. The results provide a foundation for developing and testing hypotheses about the psychology of entertainment preferences. PMID:20649744