Science.gov

Sample records for welfare equipment chromosome

  1. Chromosome

    MedlinePLUS

    Chromosomes are structures found in the center (nucleus) of cells that carry long pieces of DNA. DNA is the material that holds genes . It is the building block of the human body. Chromosomes also ...

  2. Equipment

    NASA Astrophysics Data System (ADS)

    Szumski, Michał

    This chapter describes the most important features of capillary electrophoretic equipment. A presentation of the important developments in high voltage power supplies for chip CE is followed by preparation of fused silica capillaries for use in CE. Detection systems that are used in capillary electrophoresis are widely described. Here, UV-Vis absorbance measurements are discussed including different types of detection cells—also those less popular (u-shaped, Z-shaped, mirror-coated). Fluorescence detection and laser-induced fluorescence detection are the most sensitive detection systems. Several LIF setups, such as collinear, orthogonal, confocal, and sheath-flow cuvette, are presented from the point of view of the sensitivity they can provide. Several electrochemical detectors for CE, such as conductivity, amperometric, and potentiometric, are also shown and their constructions discussed. CE-MS and much less known CE (CEC)-NMR systems are also described. The examples of automation and robotized CE systems together with their potential fields of application are also presented.

  3. Welfarism vs. extra-welfarism.

    PubMed

    Brouwer, Werner B F; Culyer, Anthony J; van Exel, N Job A; Rutten, Frans F H

    2008-03-01

    'Extra-welfarism' has received some attention in health economics, yet there is little consensus on what distinguishes it from more conventional 'welfarist economics'. In this paper, we seek to identify the characteristics of each in order to make a systematic comparison of the ways in which they evaluate alternative social states. The focus, though this is not intended to be exclusive, is on health. Specifically, we highlight four areas in which the two schools differ: (i) the outcomes considered relevant in an evaluation; (ii) the sources of valuation of the relevant outcomes; (iii) the basis of weighting of relevant outcomes and (iv) interpersonal comparisons. We conclude that these differences are substantive. PMID:18179835

  4. 45 CFR 2543.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Equipment. 2543.34 Section 2543.34 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE GRANTS AND... serial number, model number, Federal stock number, national stock number, or other identification...

  5. 45 CFR 602.32 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Equipment. 602.32 Section 602.32 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION UNIFORM ADMINISTRATIVE... of disposal and sale price of the property. (2) A physical inventory of the property must be...

  6. 45 CFR 602.32 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Equipment. 602.32 Section 602.32 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION UNIFORM ADMINISTRATIVE... of disposal and sale price of the property. (2) A physical inventory of the property must be...

  7. Welfare in horse breeding

    PubMed Central

    Campbell, M. L. H.; Sandøe, P.

    2015-01-01

    Welfare problems related to the way horses are bred, whether by coitus or by the application of artificial reproduction techniques (ARTs), have been given no discrete consideration within the academic literature. This paper reviews the existing knowledge base about welfare issues in horse breeding and identifies areas in which data is lacking. We suggest that all methods of horse breeding are associated with potential welfare problems, but also that the judicious use of ARTs can sometimes help to address those problems. We discuss how negative welfare effects could be identified and limited and how positive welfare effects associated with breeding might be maximised. Further studies are needed to establish an evidence base about how stressful or painful various breeding procedures are for the animals involved, and what the lifetime welfare implications of ARTs are for future animal generations. PMID:25908746

  8. Teenagers and Welfare Reform.

    ERIC Educational Resources Information Center

    Offner, Paul

    This report examines the extent to which welfare reform is changing adolescent behaviors that lead to welfare dependency. It begins by discussing the provisions in the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 that require teenagers to stay in school and live with a parent, concluding that relatively little can be

  9. Chromosomal Conditions

    MedlinePLUS

    ... instructions for the way your body grows and works. Genes are passed from parents to children. Each person has 23 pairs of chromosomes, or 46 in all. For each pair, you get one chromosome from your mother and one chromosome from your father. About 1 ...

  10. Modelling Farm Animal Welfare

    PubMed Central

    Collins, Lisa M.; Part, Chérie E.

    2013-01-01

    Simple Summary In this review paper we discuss the different modeling techniques that have been used in animal welfare research to date. We look at what questions they have been used to answer, the advantages and pitfalls of the methods, and how future research can best use these approaches to answer some of the most important upcoming questions in farm animal welfare. Abstract The use of models in the life sciences has greatly expanded in scope and advanced in technique in recent decades. However, the range, type and complexity of models used in farm animal welfare is comparatively poor, despite the great scope for use of modeling in this field of research. In this paper, we review the different modeling approaches used in farm animal welfare science to date, discussing the types of questions they have been used to answer, the merits and problems associated with the method, and possible future applications of each technique. We find that the most frequently published types of model used in farm animal welfare are conceptual and assessment models; two types of model that are frequently (though not exclusively) based on expert opinion. Simulation, optimization, scenario, and systems modeling approaches are rarer in animal welfare, despite being commonly used in other related fields. Finally, common issues such as a lack of quantitative data to parameterize models, and model selection and validation are discussed throughout the review, with possible solutions and alternative approaches suggested. PMID:26487411

  11. 45 CFR 1304.53 - Facilities, materials, and equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Facilities, materials, and equipment. 1304.53 Section 1304.53 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM PROGRAM...

  12. 45 CFR 1304.53 - Facilities, materials, and equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Facilities, materials, and equipment. 1304.53 Section 1304.53 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM PROGRAM...

  13. Child Welfare in Canada.

    ERIC Educational Resources Information Center

    McBroom, Elizabeth, Ed.

    1983-01-01

    Reflecting the current state of theory and practice in child welfare in Canada, these eight papers suggest a contemporary view of Canadian children and the contexts in which they develop as defined by legal rights and society. First, Henry S. Maas argues that attention to normal social development and its contexts, and to related ongoing theory

  14. Modelling Farm Animal Welfare.

    PubMed

    Collins, Lisa M; Part, Chrie E

    2013-01-01

    The use of models in the life sciences has greatly expanded in scope and advanced in technique in recent decades. However, the range, type and complexity of models used in farm animal welfare is comparatively poor, despite the great scope for use of modeling in this field of research. In this paper, we review the different modeling approaches used in farm animal welfare science to date, discussing the types of questions they have been used to answer, the merits and problems associated with the method, and possible future applications of each technique. We find that the most frequently published types of model used in farm animal welfare are conceptual and assessment models; two types of model that are frequently (though not exclusively) based on expert opinion. Simulation, optimization, scenario, and systems modeling approaches are rarer in animal welfare, despite being commonly used in other related fields. Finally, common issues such as a lack of quantitative data to parameterize models, and model selection and validation are discussed throughout the review, with possible solutions and alternative approaches suggested. PMID:26487411

  15. Children and Welfare Reform.

    ERIC Educational Resources Information Center

    Behrman, Richard E., Ed.

    2002-01-01

    This issue of "The Future of Children" examines whether programs implemented by the federal welfare reform law accomplished the goal of reducing the number of children growing up in poor, single-parent families and whether these programs benefited children. This examination coincides with debates in Congress on the reauthorization of the Personal

  16. Child Welfare Policy Manual

    ERIC Educational Resources Information Center

    Administration for Children & Families, 2008

    2008-01-01

    This document conveys mandatory policies that have their basis in Federal Law and/or program regulations. It also provides interpretations of Federal Statutes and program regulations initiated by inquiries from State Child Welfare agencies or Administration for Children and Families (ACF) Regional Offices. The manual replaces the Children's…

  17. Indian Child Welfare Program.

    ERIC Educational Resources Information Center

    Jewish Family and Children's Service, Phoenix, AZ.

    The Indian Child Welfare Program of the Jewish Family and Children's Service of Phoenix, Arizona is described. Section I provides a description of the program's organizational structure and purposes, which include adoption services, foster care and social work, a residential group home for adolescent Indian women, and a training and consultation

  18. Welfare Reform and Health

    ERIC Educational Resources Information Center

    Bitler, Marianne P.; Gelback, Jonah B.; Hoynes, Hilary W.

    2005-01-01

    A study of the effect of state and federal welfare reforms over the period 1990-2000 on health insurance coverage and healthcare utilization by single women aged between 20-45 is presented. It is observed that Personal Responsibility and Work Opportunity Act of 1996 which replaced the Aid to Families with Dependent Children program of 1990s with…

  19. Welfare Reform and Health

    ERIC Educational Resources Information Center

    Bitler, Marianne P.; Gelback, Jonah B.; Hoynes, Hilary W.

    2005-01-01

    A study of the effect of state and federal welfare reforms over the period 1990-2000 on health insurance coverage and healthcare utilization by single women aged between 20-45 is presented. It is observed that Personal Responsibility and Work Opportunity Act of 1996 which replaced the Aid to Families with Dependent Children program of 1990s with

  20. Welfare Recipients' Involvement with Child Protective Services after Welfare Reform

    ERIC Educational Resources Information Center

    Nam, Yunju; Meezan, William; Danziger, Sandra K.

    2006-01-01

    Objective: This study identifies factors associated with child protective services (CPS) involvement among current and former welfare recipients after welfare reform legislation was passed in the US in 1996. Method: Data come from the Women's Employment Study, a longitudinal study of randomly selected welfare recipients living in a Michigan city…

  1. Chromosomal Flexibility

    ERIC Educational Resources Information Center

    Journal of College Science Teaching, 2005

    2005-01-01

    Scientists have shown that a genetic element on one chromosome may direct gene activity on another. Howard Hughes Medical Institute (HHMI) researchers report that a multitasking master-control region appears to over-see both a set of its own genes and a related gene on a nearby chromosome. The findings reinforce the growing importance of location…

  2. Chromosomal Flexibility

    ERIC Educational Resources Information Center

    Journal of College Science Teaching, 2005

    2005-01-01

    Scientists have shown that a genetic element on one chromosome may direct gene activity on another. Howard Hughes Medical Institute (HHMI) researchers report that a multitasking master-control region appears to over-see both a set of its own genes and a related gene on a nearby chromosome. The findings reinforce the growing importance of location

  3. Welfare Policies and Black Families.

    ERIC Educational Resources Information Center

    Trader, Harriet Peat

    1979-01-01

    The family is an important resource for minority persons, and many minority families depend on public welfare for their survival. This article offers a compact analysis of how welfare policies often work to the disadvantage of poor Black families. (Author)

  4. Thoughts on farm animal welfare

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Gestating sow welfare remains a complex and contentious issue in the US, and stakeholders keep calling for objective, scientific welfare assessments. The Journal of the American Veterinary Medical Association recently published a Commentary that attempted to compare sow welfare in "the Swedish deep-...

  5. The Gentrification of Public Welfare.

    ERIC Educational Resources Information Center

    Dattalo, Patrick

    1992-01-01

    Notes that public welfare agencies are serving middle-class Americans. Examines six factors that may contribute to gentrification of public welfare agencies: growing demands for services from nontraditional clients; restructuring of public welfare's service delivery system; declining resources; increasing emphasis on child protective services;

  6. The Gentrification of Public Welfare.

    ERIC Educational Resources Information Center

    Dattalo, Patrick

    1992-01-01

    Notes that public welfare agencies are serving middle-class Americans. Examines six factors that may contribute to gentrification of public welfare agencies: growing demands for services from nontraditional clients; restructuring of public welfare's service delivery system; declining resources; increasing emphasis on child protective services;…

  7. Dairy animal welfare. Introduction.

    PubMed

    Blosser, T H

    1987-12-01

    Organizations devoted to proper animal care have focused the attention of society on humane animal treatment. In recent years, some groups have raised questions as to what constitutes proper animal care on the farm and in the research laboratory. Philosophical questions about animal rights have been raised. Several groups are active in the animal welfare, animal rights arena and they vary widely in their objectives and methods of operation. Many of these groups are well-funded. Some resort to civil disobedience to achieve their ends. Farm animal commodity groups, animal-oriented research agencies, and animal-related industry groups have become increasingly aware of the public interest in animal welfare and are organizing programs and groups to better understand and educate the public on the issues. PMID:3448117

  8. A measure of welfare.

    PubMed

    Harrison, P

    1979-10-01

    The Overseas Development Council has been seeking to perfect a new kind of measure for assessment of development strategies, for it has long been recognized that the Gross National Product is an inadequate measurement tool. The Physical Quality of Life Index, developed by the ODC over the past 3 years, scores nations on a scale of 0-100. It is calculated by averaging the countries' scores in 3 important fields of welfare -- adult literacy, infant mortality, and life expectancy at age 1. Although the PQLI data are averages also they do seem to be sensitive to the distribution of benefits. Results have been calculated for every country in the world, and they refute the arguments of conservative economists and political leaders who claim that basic human needs can only be met through rapid economic growth. Poor countries can achieve high levels of welfare for their population without waiting for growth in material wealth, and relatively high levels of national income can fail to guarantee that the mass of the population will have their basic needs met. In that their advance tends to slow down as countries approach the upper levels of the PQLI, the Overseas Development Council introduced a new concept -- the disparity reduction ratio -- for measuring changes in welfare. This is the annual rate at which each nation is closing the gap between its current score and the best expected score anywhere for the year 2000. The disparity reduction rate may permit exact targets to be established for progress in meeting basic needs. A worthwhile objective over the next 20 years might be for each country to halve the gap separating them from the best attainable. PMID:12261487

  9. Chromosome and cell genetics

    SciTech Connect

    Sharma, A.K.; Sharma, A.

    1985-01-01

    This book contains 11 chapters. Some of the titles are: Chromosomes in differentiation; Chromosome axis; Nuclear and organelle split genes; Chemical mutagenesis; and Chromosome architecture and additional elements.

  10. The science of animal welfare

    Technology Transfer Automated Retrieval System (TEKTRAN)

    People differ in their culture, education, economic status, and values; thus they may view an animal’s welfare status as good or poor based on their individuality. However, regardless of these human differences in perception the actual state of welfare for the animal does exist in a range from good ...

  11. Rural Dimensions of Welfare Reform.

    ERIC Educational Resources Information Center

    Weber, Bruce A., Ed.; Duncan, Greg J., Ed.; Whitener, Leslie A., Ed.

    The 16 chapters in this five-part book, each by different authors, trace the effects of welfare reform (mandated by the Personal Responsibility and Work Opportunity Reconciliation Act of 1996), upon poor people in rural areas of the United States. The book begins with an introduction called "As the Dust Settles: Welfare Reform and Rural

  12. Economic Conditions and Welfare Reform.

    ERIC Educational Resources Information Center

    Danziger, Sheldon H., Ed.

    This book contains 10 papers on three key questions regarding the effects of the 1996 Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA), which ended the Aid to Families with Dependent Children (AFDC) program: why welfare caseloads are falling; how welfare recipients are faring; and how the states are responding to changing…

  13. Substance abuse and welfare reform.

    PubMed

    Nakashian, Mary

    2002-01-01

    The Personal Responsibility and Work Opportunity Reconciliation Act of 1996 has forced welfare officials and substance abuse treatment providers to better understand the connections between substance abuse and welfare dependency. As a result, both are thinking differently about their policies and even their missions. Little is known about the true extent of substance abuse among welfare recipients, but estimates range from 2.7% to 22%. The current system of substance abuse treatment is poorly matched both to the needs of disadvantaged mothers and to the mandates of welfare reform. To help women achieve self-sufficiency, treatment programs must focus on the needs of women, address problems that often accompany substance abuse, attend to the needs of children, and emphasize work as an outcome of treatment. Welfare agencies must also change to meet their mandates; they must improve the tools and resources they offer staff, improve access and services for families, and align agency policies with new missions. PMID:11905489

  14. Welfare Reform and Substance Abuse

    PubMed Central

    Metsch, Lisa R; Pollack, Harold A

    2005-01-01

    The 1996 Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) changed the nature, purpose, and financing of public aid. Researchers, administrators, and policymakers expressed special concern about the act's impact on low-income mothers with substance use disorders. Before PRWORA's passage, however, little was known about the true prevalence of these disorders among welfare recipients or about the likely effectiveness of substance abuse treatment interventions for welfare recipients. Subsequent research documented that substance abuse disorders are less widespread among welfare recipients than was originally thought and are less common than other serious barriers to self-sufficiency. This research also showed significant administrative barriers to the screening, assessment, and referral of drug-dependent welfare recipients. This article summarizes current research findings and examines implications for welfare reform reauthorization. PMID:15787954

  15. Chromosome Analysis

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Perceptive Scientific Instruments, Inc., provides the foundation for the Powergene line of chromosome analysis and molecular genetic instrumentation. This product employs image processing technology from NASA's Jet Propulsion Laboratory and image enhancement techniques from Johnson Space Center. Originally developed to send pictures back to earth from space probes, digital imaging techniques have been developed and refined for use in a variety of medical applications, including diagnosis of disease.

  16. Animal welfare and international trade.

    PubMed

    Thiermann, A B; Babcock, S

    2005-08-01

    Globalisation is becoming a force that is revolutionising international trade, particularly that of animals and animal products. There is increasing interest in animal welfare worldwide, and as part of its 2001-2005 Strategic Plan the World Organisation for Animal Health (OIE) identified the development of international standards on animal welfare as a priority. The OIE's scientific approach to standard-setting provides the foundation for the development, and acceptance by all OIE Member Countries, of these animal welfare guidelines. The paper discusses how these guidelines on animal welfare can be implemented, both within the provisions of World Trade Organization (WTO) agreements and within the framework of voluntary codes of conduct. Even if animal welfare guidelines are not covered by any WTO agreements in the future, bi- and multilateral agreements, voluntary corporate codes, and transparent labelling of products should result in a progressive acceptance of OIE guidelines. Ultimately, consumer demands and demonstrable gains in animal production will result in an incremental evolution in animal welfare consciousness and adherence to international standards. PMID:16358524

  17. Chromosome structure and function

    SciTech Connect

    Risley, M.S.

    1986-01-01

    This book presents topics in chromosome structure and function. Topics covered include: the structure of interphase chromatin; chromatin structure, gene expression and differentiation; organization of mitotic chromosomes; organization of meiotic chromosomes and synaptonimal complexes; the lampbrush chromsome of animal oocytes; dosage compensation in mammals: x chromosome inactivation; and polytene chromosomes.

  18. Study of Chromosomes: Their Vital Importance in Agriculture, Biology, and Medicine

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Research on chromosomes has enriched the disciplines of genetics, plant breeding, biology, and medicine, which, in turn, have contributed to human welfare. Although the foundation of genetics occurred in 1865, long before the discovery of chromosomes, their subsequent discovery put genetics on a so...

  19. Relationships between chromosome structure and chromosomal aberrations

    NASA Astrophysics Data System (ADS)

    Eidelman, Yuri; Andreev, Sergey

    An interphase nucleus of human lymphocyte was simulated by the novel Monte Carlo tech-nique. The main features of interphase chromosome structure and packaging were taken into account: different levels of chromatin organisation; nonrandom localisation of chromosomes within a nucleus; chromosome loci dynamics. All chromosomes in a nucleus were modelled as polymer globules. A dynamic pattern of intra/interchromosomal contacts was simulated. The detailed information about chromosomal contacts, such as distribution of intrachromoso-mal contacts over the length of each chromosome and dependence of contact probability on genomic separation between chromosome loci, were calculated and compared to the new exper-imental data obtained by the Hi-C technique. Types and frequencies of simple and complex radiation-induced chromosomal exchange aberrations (CA) induced by X-rays were predicted with taking formation and decay of chromosomal contacts into account. Distance dependence of exchange formation probability was calculated directly. mFISH data for human lymphocytes were analysed. The calculated frequencies of simple CA agreed with the experimental data. Complex CA were underestimated despite the dense packaging of chromosome territories within a nucleus. Possible influence of chromosome-nucleus structural organisation on the frequency and spectrum of radiation-induced chromosome aberrations is discussed.

  20. ADVANCES IN ANIMAL WELFARE FOR FREE-LIVING ANIMALS.

    PubMed

    2016-04-01

    Over several decades, animal welfare has grown into its own free-standing field of scientific study, from its early beginnings in laboratory animal research to eventually include exhibited animals and farm animals. While it has always been present to some degree, consideration of animal welfare for free-ranging animals has lagged behind, developing as a field of study in the last 20 yr or so. Part of that increase was that animal welfare legislation was finally applied to studies being done on free-ranging animals. But it is the appreciation by the biologists and veterinarians working on wild animals, in which the quality of their results is largely controlled by the quality of the animals they use in their studies, which has resulted in increased attention to the well-being or welfare of the animals that they use. Other important influences driving the recognition of wildlife welfare have been changes in the public's expectations of how wild animals are dealt with, a shift in focus of wildlife professionals from managing animals that can be hunted or angled to include nongame species, the decrease in participation in hunting and fishing by members of the public, and the entry of large numbers of women into fish and wildlife agencies and departments and into veterinary medicine. Technical improvements have allowed the safe capture and handling of large or dangerous animals as immobilization drugs and equipment have been developed. The increasing use of sedating drugs allows for handling of animals with reduced stress and other impacts. A number of topics, such as toe-clipping, branding, defining which taxa can or cannot feel pain, catch-and-release fishing, and more, remain controversial within wildlife science. How we treat the wild animals that we deal with defines who we are as wildlife professionals, and animal welfare concerns and techniques for free-ranging animals will continue to develop and evolve. PMID:26845298

  1. Human chromosome 8.

    PubMed Central

    Wood, S

    1988-01-01

    The role of human chromosome 8 in genetic disease together with the current status of the genetic linkage map for this chromosome is reviewed. Both hereditary genetic disease attributed to mutant alleles at gene loci on chromosome 8 and neoplastic disease owing to somatic mutation, particularly chromosomal translocations, are discussed. PMID:3070042

  2. What Works in Child Welfare.

    ERIC Educational Resources Information Center

    Kluger, Miriam P., Ed.; Alexander, Gina, Ed.; Curtis, Patrick A., Ed.

    Noting the importance of identifying the effectiveness of child welfare programs for future policy planning, this book examines features of successful programs. The book is presented in six sections: family preservation and family support services, child protective services, out-of-home care, adoption, child care, and adolescent services. Each

  3. Interagency Collaboration and Welfare Reform.

    ERIC Educational Resources Information Center

    Sussman, Tara

    2000-01-01

    This issue of WIN (Welfare Information Network) Issue Notes raises some major issues that agencies may want to address as they consider expanding collaborative efforts. It describes collaborative efforts and identifies resources that could prove useful in designing successful collaborations. Section 1 offers background. Section 2 answers these…

  4. Laboratory Animal Welfare Supplement IV.

    ERIC Educational Resources Information Center

    Gluckstein, Fritz P., Comp.

    This document is the fourth supplement to a 1984 bibliography on laboratory animal welfare. Items presented were selected because they represent some of the most significant of those providing recent information or because they were considered useful. The period covered is October, 1986 through October, 1987. Monographs, conference proceedings,…

  5. Developmental Disabilities and Child Welfare.

    ERIC Educational Resources Information Center

    Rycus, Judith S.; Hughes, Ronald C.

    This monograph addresses common misconceptions about developmental disabilities, describes the conditions that child welfare workers are most likely to see, provides examples of effective interventions, and stresses the importance of early intervention to promote healthy development. Specific chapters include: (1) "Understanding Developmental

  6. Data Mining in Child Welfare.

    ERIC Educational Resources Information Center

    Schoech, Dick; Quinn, Andrew; Rycraft, Joan R.

    2000-01-01

    Examines the historical and larger context of data mining and describes data mining processes, techniques, and tools. Illustrates these using a child welfare dataset concerning the employee turnover that is mined, using logistic regression and a Bayesian neural network. Discusses the data mining process, the resulting models, their predictive…

  7. Is Welfare Bad for Children?

    ERIC Educational Resources Information Center

    Macaulay, Jacqueline

    A major fear of many who are concerned with the welfare system is that the system itself tends to create pathology among recipients, and in the case of children, to cause mal-socialization. There are a number of problems with these assertions. The chief problem is that there is not much good evidence, one way or another, concerning the effects of

  8. Data Mining in Child Welfare.

    ERIC Educational Resources Information Center

    Schoech, Dick; Quinn, Andrew; Rycraft, Joan R.

    2000-01-01

    Examines the historical and larger context of data mining and describes data mining processes, techniques, and tools. Illustrates these using a child welfare dataset concerning the employee turnover that is mined, using logistic regression and a Bayesian neural network. Discusses the data mining process, the resulting models, their predictive

  9. Welfare Entitlements: Addressing New Realities.

    ERIC Educational Resources Information Center

    Belcher, Jon R.; Fandetti, Donald V.

    1995-01-01

    Because welfare entitlements are increasingly unpopular, social work advocates need to place greater emphasis on job growth and alternate mechanisms for wealth redistribution, including refundable tax credits for working poor people. The Internal Revenue Code can be an effective weapon in combating poverty if antipoverty approaches in the code are…

  10. Progressing beyond the Welfare State.

    ERIC Educational Resources Information Center

    Benson, Lee; Harkavy, Ira

    1991-01-01

    This paper outlines a neo-Deweyan strategy to transform American public schools into genuine community schools that function as central agencies for the development of a democratic welfare society. John Dewey's thesis was that a well-functioning school system constitutes the necessary, though not sufficient, condition for a well-functioning…

  11. Welfare Reform: Serving America's Children.

    ERIC Educational Resources Information Center

    Moynihan, Daniel Patrick

    1989-01-01

    The poorest group in our population is children. This article discusses past and present public assistance programs that affect children and the disproportionate number of minority group children and children in single-parent homes who live in poverty. The need for welfare reform is discussed also. (IAH)

  12. What Works in Child Welfare.

    ERIC Educational Resources Information Center

    Kluger, Miriam P., Ed.; Alexander, Gina, Ed.; Curtis, Patrick A., Ed.

    Noting the importance of identifying the effectiveness of child welfare programs for future policy planning, this book examines features of successful programs. The book is presented in six sections: family preservation and family support services, child protective services, out-of-home care, adoption, child care, and adolescent services. Each…

  13. Air quality and human welfare

    NASA Astrophysics Data System (ADS)

    Sundseth, K.; Pacyna, J. M.; Pacyna, E. G.

    2009-02-01

    Human welfare is generally referring to allocation of resources to fit the well being of humans. If high standard of well-being is to be maintained, the concerns for a healthy environment must be balanced against requirements of economic growth. In a natural capital system, human welfare is best served by improving the quality and flow of desired services delivered rather than merely increasing the total money flow. An ecosystem based management of living and natural resource use will steer this progress to the best of human welfare while the efficiency of ecosystem based management depends strongly on the availability of integrated assessment tools that will combine environmental models and monitoring data with ecological economic valuation methods. In applied welfare economics, the methodological approach to assess resource allocations towards societal optimality and thereby establish criteria for government intervention is often linked to tools as Cost-ffectiveness Analysis (CEA), Cost-Benefit Assessment (CBA) or Multi-criteria Analysis (MCA). By illustrating an assessment on costs and benefits of the implementation of Hg emission reduction measures in the coal sector, it becomes obvious that for a full analysis of societal costs and benefits, several aspects of Hg pollution, sources, impacts and co-benefits need to be considered.

  14. Mitotic chromosome structure

    SciTech Connect

    Heermann, Dieter W.

    2012-07-15

    Mounting evidence is compiling linking the physical organizational structure of chromosomes and the nuclear structure to biological function. At the base of the physical organizational structure of both is the concept of loop formation. This implies that physical proximity within chromosomes is provided for otherwise distal genomic regions and thus hierarchically organizing the chromosomes. Together with entropy many experimental observations can be explained with these two concepts. Among the observations that can be explained are the measured physical extent of the chromosomes, their shape, mechanical behavior, the segregation into territories (chromosomal and territories within chromosomes), the results from chromosome conformation capture experiments, as well as linking gene expression to structural organization.

  15. 45 CFR 95.641 - Applicability of rules for charging equipment in Subpart G of this part.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Automatic Data Processing Equipment and Services-Conditions... 45 Public Welfare 1 2010-10-01 2010-10-01 false Applicability of rules for charging equipment in... equipment in Subpart G of this part. ADP equipment, as well as other equipment acquired under...

  16. 45 CFR 95.641 - Applicability of rules for charging equipment in Subpart G of this part.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Automatic Data Processing Equipment and Services-Conditions... 45 Public Welfare 1 2014-10-01 2014-10-01 false Applicability of rules for charging equipment in... equipment in Subpart G of this part. ADP equipment, as well as other equipment acquired under...

  17. 45 CFR 95.641 - Applicability of rules for charging equipment in Subpart G of this part.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Automatic Data Processing Equipment and Services-Conditions... 45 Public Welfare 1 2012-10-01 2012-10-01 false Applicability of rules for charging equipment in... equipment in Subpart G of this part. ADP equipment, as well as other equipment acquired under...

  18. 45 CFR 95.641 - Applicability of rules for charging equipment in Subpart G of this part.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Automatic Data Processing Equipment and Services-Conditions... 45 Public Welfare 1 2013-10-01 2013-10-01 false Applicability of rules for charging equipment in... equipment in Subpart G of this part. ADP equipment, as well as other equipment acquired under...

  19. 45 CFR 95.641 - Applicability of rules for charging equipment in Subpart G of this part.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Automatic Data Processing Equipment and Services-Conditions... 45 Public Welfare 1 2011-10-01 2011-10-01 false Applicability of rules for charging equipment in... equipment in Subpart G of this part. ADP equipment, as well as other equipment acquired under...

  20. Chromosome Oscillations in Mitosis

    NASA Astrophysics Data System (ADS)

    Camps, Otger; Sens, Pierre

    2006-09-01

    The motion and positioning of chromosomes during eukaryotic cell division is investigated theoretically. We perform a self-contained analysis where the motion of mono-oriented chromosomes results from the competition between the kinetochore and chromokinesin motors on the chromosome arms. We show that the interplay between the asterlike morphology of the mitotic spindle and the collective dynamics of motors accounts for chromosome motion, positioning, and congression. In particular, the characteristic oscillations of chromosomes observed in vivo arise naturally within this description.

  1. Text, Lies, and the Welfare State: The Portrayal of Welfare Recipients in Welfare-to-Work Educational Programs.

    ERIC Educational Resources Information Center

    Sandlin, Jennifer A.

    A study analyzed the ideological messages about welfare recipients promoted in two welfare-to-work educational programs. Data were collected through interviews with students, teachers, and administrators at an adult literacy classroom serving unemployed women on welfare and an employment preparation program designed to increase job skills of women

  2. 45 CFR 95.707 - Equipment management and disposition.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... (a) An item of equipment is subject to the property rules in subpart O of 45 CFR part 74 if the total... charged to more than one program) are not subject to the specific requirements in subpart O of 45 CFR part... 45 Public Welfare 1 2010-10-01 2010-10-01 false Equipment management and disposition....

  3. Welfare Rights in the Liberal Tradition.

    ERIC Educational Resources Information Center

    Horne, Thomas A.

    1990-01-01

    Maintains that welfare rights are not incompatible with liberalism's commitment to private property and freedom. Argues that students need to be aware of liberalism's favorable historical position on welfare. Examines the positions of John Locke, Thomas Paine, and John Stuart Mills on poverty, welfare, and the role of the state. (RW)

  4. Linking Chromosome Duplication and Segregation via Sister Chromatid Cohesion

    PubMed Central

    Leman, Adam R.; Noguchi, Eishi

    2014-01-01

    DNA replication during S phase generates two identical copies of each chromosome. Each chromosome is destined for a daughter cell, but each daughter must receive one and only one copy of each chromosome. To ensure accurate chromosome segregation, eukaryotic cells are equipped with a mechanism to pair the chromosomes during chromosome duplication and hold the pairs until a bi-oriented mitotic spindle is formed and the pairs are pulled apart. This mechanism is known as sister chromatid cohesion, and its actions span the entire cell cycle. During G1, before DNA is copied during S phase, proteins termed cohesins are loaded onto DNA. Paired chromosomes are held together through G2 phase, and finally the cohesins are dismantled during mitosis. The processes governing sister chromatid cohesion ensure that newly replicated sisters are held together from the moment they are generated to the metaphase–anaphase transition, when sisters separate. PMID:24906310

  5. Comparing Drug Use between Welfare-Receiving Arrestees and Non-Welfare-Receiving Arrestees.

    ERIC Educational Resources Information Center

    Yacoubian, George S., Jr.; Peters, Ronald J., Jr.; Urbach, Blake J.; Johnson, Regina J.

    2002-01-01

    Compares drug-positive rates between welfare-receiving arrestees, non-welfare receiving arrestees living below the poverty level, and non-welfare arrestees living above the poverty level. Welfare-receiving arrestees were more likely to be female, older, less educated, and to test positive for opiates and benzodiazepines than the other subgroups.

  6. Comparing Drug Use between Welfare-Receiving Arrestees and Non-Welfare-Receiving Arrestees.

    ERIC Educational Resources Information Center

    Yacoubian, George S., Jr.; Peters, Ronald J., Jr.; Urbach, Blake J.; Johnson, Regina J.

    2002-01-01

    Compares drug-positive rates between welfare-receiving arrestees, non-welfare receiving arrestees living below the poverty level, and non-welfare arrestees living above the poverty level. Welfare-receiving arrestees were more likely to be female, older, less educated, and to test positive for opiates and benzodiazepines than the other subgroups.…

  7. B-chromosome evolution.

    PubMed Central

    Camacho, J P; Sharbel, T F; Beukeboom, L W

    2000-01-01

    B chromosomes are extra chromosomes to the standard complement that occur in many organisms. They can originate in a number of ways including derivation from autosomes and sex chromosomes in intra- and interspecies crosses. Their subsequent molecular evolution resembles that of univalent sex chromosomes, which involves gene silencing, heterochromatinization and the accumulation of repetitive DNA and transposons. B-chromosome frequencies in populations result from a balance between their transmission rates and their effects on host fitness. Their long-term evolution is considered to be the outcome of selection on the host genome to eliminate B chromosomes or suppress their effects and on the B chromosome's ability to escape through the generation of new variants. Because B chromosomes interact with the standard chromosomes, they can play an important role in genome evolution and may be useful for studying molecular evolutionary processes. PMID:10724453

  8. The Precarious Prokaryotic Chromosome

    PubMed Central

    2014-01-01

    Evolutionary selection for optimal genome preservation, replication, and expression should yield similar chromosome organizations in any type of cells. And yet, the chromosome organization is surprisingly different between eukaryotes and prokaryotes. The nuclear versus cytoplasmic accommodation of genetic material accounts for the distinct eukaryotic and prokaryotic modes of genome evolution, but it falls short of explaining the differences in the chromosome organization. I propose that the two distinct ways to organize chromosomes are driven by the differences between the global-consecutive chromosome cycle of eukaryotes and the local-concurrent chromosome cycle of prokaryotes. Specifically, progressive chromosome segregation in prokaryotes demands a single duplicon per chromosome, while other precarious features of the prokaryotic chromosomes can be viewed as compensations for this severe restriction. PMID:24633873

  9. USGS Equipment

    USGS Multimedia Gallery

    USGS traveling equipment above Minot, North Dakota. USGS personnel were measuring the streamflow of the Souris River above Minot, NDon June 24, 2011.Streamflow was approximately 20,800 cubic feet per second, stage approximately 23.46 feet....

  10. Telescope Equipment

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Renaissance Telescope for high resolution and visual astronomy has five 82-degree Field Tele-Vue Nagler Eyepieces, some of the accessories that contribute to high image quality. Telescopes and eyepieces are representative of a family of optical equipment manufactured by Tele-Vue Optics, Inc.

  11. Challenges in assessing fish welfare.

    PubMed

    Volpato, Gilson L

    2009-01-01

    Descriptions of feeling states in nonhuman animals have relied on indirect evidence from empirical data. Assumptions that fish do not experience suffering lack evidence and in fact contradict a large body of indirect scientific evidence and ethical concern. Why should the burden of proof rest on those defending the hypothesis that fish feel pain and other discomfort? In this article I address this controversy and describe typical methodsand the problems associated with themto identify animal welfare (feeling-based, physiological, and behavioral approaches intended to demonstrate feelings and welfare states). Then I urge a shift in scientific focus from efforts to either identify an internal state of well-being or determine whether an organism suffers, to efforts to identify conditions that promote a "good state" for an animal (i.e., a state it would choose). For this approach, I discuss preference tests and their implications for scientific research, teaching, aquarism, and fishing. PMID:19949249

  12. [Guardians of the welfare state?].

    PubMed

    Nessa, J

    1996-08-30

    The welfare state in post-war Norwegian society is a result of the dominating social democratic ideology now adapted to far-reaching technological development. Increased spending on health has provoked the question of whether doctors should be the guardians of the welfare state against inappropriate demands from patients. This paper argues against this view. What is really a problem for the whole society cannot be solved on the individual level. In many ways, to be sick is to fall outside the community, with a real risk of loosing rights and duties essential to all of us. The doctor has to find-and redefine-his ancient role of spokesman and champion, and of serving as a friendly and emphatic corrective to the individual patient. This is particularly important in modern health services where having to face interpersonal problems is a key element of everyday practice. PMID:8928107

  13. Welfare to be the keynote.

    PubMed

    Narain, R

    1977-01-01

    The Policy Statement on the Family Welfare Program underlnes the Indian government's decision not to have any compulsory sterilization at either the state or national level. Free sterilization will be provided for those who want it and a cash payment will be made to offset the cost of the visit to the clinic. However, family planning will be only a minor part of the new Family Welfare Program. All aspects of family welfare, but particularly health of mothers and children, msut be implemented. Training of indigenous midwives to provide maternity services to all poor women will be started. Since there is a direct correlation between illiteracy and fertility and between infant and maternal mortality and age of marriage, the Government will present legislation to raise the minimum age of marriage for girls to 18 years and for boys to 21. Highlighting the alarming growth rate of India's population, the policy statement cautioned that the country would be near 1 billion population by the end of the century. Cooperation of media, women's groups, trade unions, and all aspects of society is needed to promote the benefits to the family and to the nation of family planning. PMID:12260195

  14. Behavioural indicators of welfare in farmed fish.

    PubMed

    Martins, Catarina I M; Galhardo, Leonor; Noble, Chris; Damsgrd, Brge; Spedicato, Maria T; Zupa, Walter; Beauchaud, Marilyn; Kulczykowska, Ewa; Massabuau, Jean-Charles; Carter, Toby; Planellas, Snia Rey; Kristiansen, Tore

    2012-02-01

    Behaviour represents a reaction to the environment as fish perceive it and is therefore a key element of fish welfare. This review summarises the main findings on how behavioural changes have been used to assess welfare in farmed fish, using both functional and feeling-based approaches. Changes in foraging behaviour, ventilatory activity, aggression, individual and group swimming behaviour, stereotypic and abnormal behaviour have been linked with acute and chronic stressors in aquaculture and can therefore be regarded as likely indicators of poor welfare. On the contrary, measurements of exploratory behaviour, feed anticipatory activity and reward-related operant behaviour are beginning to be considered as indicators of positive emotions and welfare in fish. Despite the lack of scientific agreement about the existence of sentience in fish, the possibility that they are capable of both positive and negative emotions may contribute to the development of new strategies (e.g. environmental enrichment) to promote good welfare. Numerous studies that use behavioural indicators of welfare show that behavioural changes can be interpreted as either good or poor welfare depending on the fish species. It is therefore essential to understand the species-specific biology before drawing any conclusions in relation to welfare. In addition, different individuals within the same species may exhibit divergent coping strategies towards stressors, and what is tolerated by some individuals may be detrimental to others. Therefore, the assessment of welfare in a few individuals may not represent the average welfare of a group and vice versa. This underlines the need to develop on-farm, operational behavioural welfare indicators that can be easily used to assess not only the individual welfare but also the welfare of the whole group (e.g. spatial distribution). With the ongoing development of video technology and image processing, the on-farm surveillance of behaviour may in the near future represent a low-cost, noninvasive tool to assess the welfare of farmed fish. PMID:21796377

  15. Chromosome Disorder Outreach

    MedlinePLUS

    Forgot Password? General Info About CDO Intro To Chromosomes Registered Disorders Contact Us Privacy & Disclaimer Ask The ... Medical Glossary YOU can Help Awareness Family Support Chromosome Specific Support Groups Locate A Genetic Counselor CDO ...

  16. Abnormal human sex chromosome constitutions

    SciTech Connect

    1993-12-31

    Chapter 22, discusses abnormal human sex chromosome constitution. Aneuploidy of X chromosomes with a female phenotype, sex chromosome aneuploidy with a male phenotype, and various abnormalities in X chromosome behavior are described. 31 refs., 2 figs.

  17. Chromosomal development of cancer

    SciTech Connect

    1993-12-31

    Chapter 30, describes the chromosomal development of cancer. It has been established through cytological research that the number of chromosomes in cancer cells often deviates greatly from the usual number in healthy cells of the host organism. This chapter includes discussions on chromosome studies in ascites tumors, stemline and tumor development, mitotic aberrations in cancer, and selection and tumor progression. 25 refs., 2 figs.

  18. Chromosomal Disorders and Autism.

    ERIC Educational Resources Information Center

    Gillberg, Christopher

    1998-01-01

    This paper reviews the literature on chromosomal aberrations in autism, especially possible gene markers. It notes that Chromosome 15 and numerical and structural abnormalities of the sex chromosomes have been most frequently reported as related to the genesis of autism. (Author/DB)

  19. Mapping strategies: Chromosome 16 workshop

    SciTech Connect

    Not Available

    1989-01-01

    The following topics from a workshop on chromosome 16 are briefly discussed: genetic map of chromosome 16; chromosome breakpoint map of chromosome 16; integrated physical/genetic map of chromosome 16; pulsed field map of the 16p13.2--p13.3 region (3 sheets); and a report of the HGM10 chromosome 16 committee.

  20. Welfare Gains from Financial Liberalization

    PubMed Central

    Townsend, Robert M.; Ueda, Kenichi

    2010-01-01

    Financial liberalization has been a controversial issue, as empirical evidence for growth enhancing effects is mixed. Here, we find sizable welfare gains from liberalization (cost to repression), though the gain in economic growth is ambiguous. We take the view that financial liberalization is a government policy that alters the path of financial deepening, while financial deepening is endogenously chosen by agents given a policy and occurs in transition towards a distant steady state. This history-dependent view necessitates the use of simulation analysis based on a growth model. Our application is a specific episode: Thailand from 1976 to 1996. PMID:20806055

  1. Chromosome instability syndromes

    SciTech Connect

    1993-12-31

    Chapter 11, discusses chromosome instability syndromes. The focus is on the most extensively studied genotypic chromosomal aberrations which include Bloom syndrome, Fanconi anemia, ataxia telangiectasia, and xeroderma pigmentosum. The great interest in these syndromes is out of proportion to their rare occurrence; however, studies of genotypic chromosome breakage have been inspired by the hope of throwing light on chromosome structure and behavior. A table is given which relates chromosomal aberrations in Bloom syndrome which may cause or promote cancer. 34 refs., 3 figs., 1 tab.

  2. A Universal Animal Welfare Framework for Zoos.

    PubMed

    Kagan, Ron; Carter, Scott; Allard, Stephanie

    2015-01-01

    The Detroit Zoological Society's (DZS) Center for Zoo Animal Welfare (CZAW) was created to advance the science and policy of the welfare of exotic nonhuman animals in captivity. This important part of the DZS mission is achieved through assessments of, and research on, the welfare of animals in zoos; by recognizing extraordinary achievement in the advancement of animal welfare; by widely sharing knowledge through a bibliographic resource center; by conducting professional training for animal care staff; and by convening important discussions in the form of international symposia. This special issue of the Journal of Applied Animal Welfare Science features selected papers from the most recent international CZAW symposium held at the Detroit Zoo in November 2014, as well as a universal framework for zoo animal welfare developed by the DZS. PMID:26440493

  3. A Universal Animal Welfare Framework for Zoos

    PubMed Central

    Kagan, Ron; Carter, Scott; Allard, Stephanie

    2015-01-01

    The Detroit Zoological Society's (DZS) Center for Zoo Animal Welfare (CZAW) was created to advance the science and policy of the welfare of exotic nonhuman animals in captivity. This important part of the DZS mission is achieved through assessments of, and research on, the welfare of animals in zoos; by recognizing extraordinary achievement in the advancement of animal welfare; by widely sharing knowledge through a bibliographic resource center; by conducting professional training for animal care staff; and by convening important discussions in the form of international symposia. This special issue of the Journal of Applied Animal Welfare Science features selected papers from the most recent international CZAW symposium held at the Detroit Zoo in November 2014, as well as a universal framework for zoo animal welfare developed by the DZS. PMID:26440494

  4. Preparing Social Work Students for Rural Child Welfare Practice: Emerging Curriculum Competencies

    ERIC Educational Resources Information Center

    Riebschleger, Joanne; Norris, Debra; Pierce, Barbara; Pond, Debora L.; Cummings, Cristy

    2015-01-01

    Multiple issues that are unique to child welfare social work practice in rural areas markedly affect workforce recruitment and retention, yet little attention is given to the proficiencies needed to equip emerging social workers for this growing area of the field. Curriculum content is needed that provides students with the opportunity to master

  5. Preparing Social Work Students for Rural Child Welfare Practice: Emerging Curriculum Competencies

    ERIC Educational Resources Information Center

    Riebschleger, Joanne; Norris, Debra; Pierce, Barbara; Pond, Debora L.; Cummings, Cristy

    2015-01-01

    Multiple issues that are unique to child welfare social work practice in rural areas markedly affect workforce recruitment and retention, yet little attention is given to the proficiencies needed to equip emerging social workers for this growing area of the field. Curriculum content is needed that provides students with the opportunity to master…

  6. Animal welfare at the group level: more than the sum of individual welfare?

    PubMed

    Ohl, F; Putman, R J

    2014-03-01

    Currently assessment and management of animal welfare are based on the supposition that welfare status is something experienced identically by each individual animal when exposed to the same conditions. However, many authors argue that individual welfare cannot be seen as an 'objective' state, but is based on the animal's own self-perception; such perception might vary significantly between individuals which appear to be exposed to exactly the same challenges. We argue that this has two implications: (1) actual perceived welfare status of individuals in a population may vary over a wide range even under identical environmental conditions; (2) animals that appear to an external observer to be in better or poorer welfare condition may all in fact perceive their own individual status as the same. This would imply that optimum welfare of a social group might be achieved in situations where individual group members differ markedly in apparent welfare status and perceive their own welfare as being optimal under differing circumstances. Welfare phenotypes may also vary along a continuum between self-regarding and other-regarding behaviour; a variety of situations exist where (social) individuals appear to invest in the welfare of other individuals instead of maximising their own welfare; in such a case it is necessary to re-evaluate individual welfare within the context of a social group and recognise that there may be consequences for the welfare of individuals, of decisions made at the group level or by other group members. PMID:24114179

  7. The climate of child welfare employee retention.

    PubMed

    Cahalane, Helen; Sites, Edward W

    2008-01-01

    This article describes differences in perceptions of the child welfare work environment among Title IV-E educated individuals who remain within public child welfare and those who sought employment elsewhere after fulfilling a legal work commitment. Job satisfaction, emotional exhaustion, and personal accomplishment were predictive of staying versus leaving. The empirical evidence suggests that efforts to retain highly skilled and educated public child welfare workers should focus on creating positive organizational climates within agencies. PMID:18575259

  8. Welfare to Work. Technical Assistance Packet.

    ERIC Educational Resources Information Center

    Join Together, Boston, MA.

    "Welfare to work" is an issue in the substance abuse field because of the high number of people on welfare who have a substance abuse problem. One-fourth of women on welfare either abuse or are addicted to alcohol or other drugs. For women ages 18-24 the incidence is as high as 37%, according to the Center on Addiction and Substance Abuse.

  9. Drivers for animal welfare policies in Europe.

    PubMed

    Dalla Villa, P; Matthews, L R; Alessandrini, B; Messori, S; Migliorati, G

    2014-04-01

    The European region has been, and remains, a global leader in the development of animal welfare policies. The region has a great diversity of cultures and religions, different levels of socio-economic development, and varied legislation, policies and practices. Nevertheless, there are common drivers for animal welfare policy based on a history of animal welfare ethics and obligations to animal users and society in general. A unifying goal of countries in the region is to achieve sustainable compliance with the World Organisation for Animal Health (OIE) standards on animal health and welfare. Ethics isthe overarching driver, supported by the actions of governmental, inter-governmental and non-governmental activities, markets and trade, science and knowledge. Historically, organisations involved in promoting animal welfare have tended to act in isolation. For example, non-governmental organisations (NGOs) have run campaigns to influence retailers and the welfare policies of their farmer suppliers. Increasingly, different organisations with common or complementary goals are working together. For example, competent authorities, inter-governmental bodies and NGOs have combined their efforts to address dog population control across several countries in the region. Also, animal welfare is becoming integrated into the corporate social responsibility targets of private companies. Science and knowledge, as drivers and tools, are assisting with the harmonisation of welfare standards, e.g. by providing a common basis for measuring welfare impacts through animal-based measures and widespread sharing of this information. Current trends suggest that there will be greater collaboration among the organisations driving change, and increasing convergence of animal welfare strategies and welfare assessment tools. The result will be increased harmonisation of animal welfare standards throughout the region. PMID:25000776

  10. Welfare reform: from illusion to reality.

    PubMed

    Stoesz, D; Karger, H J

    1990-03-01

    Welfare reform is a concept that has a relatively narrow meaning in the United States, because it is associated with the Aid to Families with Dependent Children (AFDC) program. Since the 1960s, several attempts have been made to reform AFDC, but it was not until 1988 that the program was changed substantially. The alterations in the AFDC program reflect an ideological shift in American culture that is increasingly conservative. Social welfare policy as a whole has begun to reflect conservative values by emphasizing reciprocity, productivity, and familial responsibility. A myriad of important social welfare issues remain unresolved despite the new welfare reform bill of 1988. PMID:2191449

  11. Animal welfare and use of silkworm as a model animal.

    PubMed

    Sekimizu, N; Paudel, A; Hamamoto, H

    2012-08-01

    Sacrificing model animals is required for developing effective drugs before being used in human beings. In Japan today, at least 4,210,000 mice and other mammals are sacrificed to a total of 6,140,000 per year for the purpose of medical studies. All the animals treated in Japan, including test animals, are managed under control of "Act on Welfare and Management of Animals". Under the principle of this Act, no person shall kill, injure, or inflict cruelty on animals without due cause. "Animal" addressed in the Act can be defined as a "vertebrate animal". If we can make use of invertebrate animals in testing instead of vertebrate ones, that would be a remarkable solution for the issue of animal welfare. Furthermore, there are numerous advantages of using invertebrate animal models: less space and small equipment are enough for taking care of a large number of animals and thus are cost-effective, they can be easily handled, and many biological processes and genes are conserved between mammals and invertebrates. Today, many invertebrates have been used as animal models, but silkworms have many beneficial traits compared to mammals as well as other insects. In a Genome Pharmaceutical Institute's study, we were able to achieve a lot making use of silkworms as model animals. We would like to suggest that pharmaceutical companies and institutes consider the use of the silkworm as a model animal which is efficacious both for financial value by cost cutting and ethical aspects in animals' welfare. PMID:23006994

  12. Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation.

    PubMed

    Levesque, Marshall J; Raj, Arjun

    2013-03-01

    We report intron chromosomal expression FISH (iceFISH), a multiplex imaging method for measuring gene expression and chromosome structure simultaneously on single chromosomes. We find substantial differences in transcriptional frequency between genes on a translocated chromosome and the same genes in their normal chromosomal context in the same cell. Correlations between genes on a single chromosome pointed toward a cis chromosome-level transcriptional interaction spanning 14.3 megabases. PMID:23416756

  13. Preimplantation genetic diagnosis and the welfare of the child.

    PubMed

    Lavery, Stuart

    2004-12-01

    Preimplantation genetic diagnosis is a form of very early prenatal diagnosis. The technique combines assisted reproductive technology with molecular genetics and cytogenetics to allow the identification of abnormalities in embryos prior to implantation. Since its introduction in 1990 this approach has been applied to an increasing number of single gene disorders, chromosomal rearrangements, and more recent indications such as aneuploidy screening and HLA matching. Since its inception the technology has attracted much attention: geneticists have expressed concerns about the robustness and validity of diagnosis based on single cell analysis, perinatologists were anxious about the effect of embryo biopsy on normal fetal development; and philosophers and ethicists have argued the cases for and against embryo selection. This article attempts to highlight the difficult choices and ethical challenges confronting patients and clinicians in an effort to balance the recognition of parental autonomy with the obligation of clinics to consider the welfare of any child born as a result of this treatment. PMID:15621895

  14. Public Welfare and Work Incentives: Theory and Practice. Studies in Public Welfare. Paper No. 14.

    ERIC Educational Resources Information Center

    Burke, Vee; Townsend, Alair A.

    This chart book summarizes two volumes in the subcommittee's series, "Studies in Public Welfare." Paper No. 4 (Dec. 22, 1972) explored work incentive and disincentive features in existing and proposed public welfare programs (cash welfare, unemployment insurance, social security, veterans' benefits, food stamps, public housing, and medicaid).…

  15. Societal Factors Impacting Child Welfare: Validating the Perceptions of Child Welfare Scale

    ERIC Educational Resources Information Center

    Auerbach, Charles; Zeitlin, Wendy; Augsberger, Astraea; McGowan, Brenda G.; Claiborne, Nancy; Lawrence, Catherine K.

    2015-01-01

    Objective: This research examines the psychometric properties of the Perceptions of Child Welfare Scale (PCWS). This instrument is designed to assess child welfare workers' understanding of how society views their role and their work. Methods: Confirmatory factor analysis (CFA) was utilized to analyze data on 538 child welfare workers. Results:

  16. Welfare Reform in Missouri. A Report of the Welfare Reform Committee.

    ERIC Educational Resources Information Center

    De Simone, Peter, Ed.; Kunz, Julia, Ed.

    This report outlines findings and recommendations of a committee study of whether the State of Missouri is in need of welfare reform. The major finding is that Missouri's current welfare system is substantially deficient and requires correction of laws, policies, practices, and resource allocation. Three major themes are the following: (1) welfare

  17. Deterioration of Child Welfare Families under Conditions of Welfare Reform. JCPR Working Paper.

    ERIC Educational Resources Information Center

    Wells, Kathleen; Guo, Shenyang; Shafran, Robert D.; Pearlmutter, Susan

    At the time the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (P. L. 104-193) was being debated, some child welfare advocates raised the concern that its effect on families at high risk of involvement in the child welfare system or on families already involved in the child welfare system would be negative. As the debate…

  18. Importing the Poor: Welfare Magnetism and Cross-Border Welfare Migration

    ERIC Educational Resources Information Center

    Journal of Human Resources, 2005

    2005-01-01

    A study of the welfare programs in two counties bordering different states along with comparative welfare expenditure in interior counties tests the theory that Aid for Families with Dependent Children (AFDC) recipients migrate to counties which have a higher per capita welfare budget. Research shows that border counties with a $100 differential

  19. Welfare Reform and Children's Health.

    PubMed

    Baltagi, Badi H; Yen, Yin-Fang

    2016-03-01

    This study investigates the effect of the Temporary Aid to Needy Families (TANF) program on children's health outcomes using data from the Survey of Income and Program Participation over the period 1994 to 2005. The TANF policies have been credited with increased employment for single mothers and a dramatic drop in welfare caseload. Our results show that these policies also had a significant effect on various measures of children's medical utilization among low-income families. These health measures include a rating of the child's health status reported by the parents, the number of times that parents consulted a doctor, and the number of nights that the child stayed in a hospital. We compare the overall changes of health status and medical utilization for children with working and nonworking mothers. We find that the child's health status as reported by the parents is affected by the maternal employment status. Copyright © 2014 John Wiley & Sons, Ltd. PMID:25533889

  20. Welfare indicators during broiler slaughtering.

    PubMed

    Grilli, C; Loschi, A R; Rea, S; Stocchi, R; Leoni, L; Conti, F

    2015-01-01

    1. The aim of this study was to identify the most relevant welfare indicators for unloading, lairage, stunning, killing and post-mortem inspection in a poultry slaughter plant. Different indicators were unloading duration, lairage time, environmental variables in the lairage facilities, shackling time and electrical variables used in the water bath. 2. Lairage time did not correlate strongly with dead on arrival. Heat stress was limited by means of ventilation systems, correct cage placement and appropriate stocking density per crate. The acceptable shackling period was about 30 s. 3. The presence of a corneal reflex showed that an animal was alive, while spontaneous wing flapping, spontaneous eye blinking and response to a painful stimulus were regarded as indicators of stunning efficiency. 4. It was concluded that the presence of recent traumatic injuries during the post-mortem inspection could be a valid means to establish whether corrective measures concerning the handling, transport and loading procedures should be taken. PMID:25567419

  1. Welfare: Its Relationship to Social Origins. Personal and Family Characteristics.

    ERIC Educational Resources Information Center

    Ensminger, Margaret E.

    An attempt was made to identify variables associated with black mothers in a high risk community who stayed on welfare, who moved off welfare, who moved on and off welfare, and who did not participate in welfare. Three kinds of variables were explored to explain such variations in welfare participation: (1) social origin characteristics, (2)…

  2. Mechanisms for chromosome segregation.

    PubMed

    Bouet, Jean-Yves; Stouf, Mathieu; Lebailly, Elise; Cornet, François

    2014-12-01

    Bacteria face the problem of segregating their gigantic chromosomes without a segregation period restricted in time and space, as Eukaryotes do. Segregation thus involves multiple activities, general or specific of a chromosome region and differentially controlled. Recent advances show that these various mechanisms conform to a “pair and release” rule, which appears as a general rule in DNA segregation. We describe the latest advances in segregation of bacterial chromosomes with emphasis on the different pair and release mechanisms. PMID:25460797

  3. Can Work Alter Welfare Recipients' Beliefs?

    ERIC Educational Resources Information Center

    Gottschalk, Peter

    2005-01-01

    A common argument in support of work-based welfare reform is that exposure to work will lead welfare recipients to revise their beliefs about how they will be treated in the labor market. This paper explores the analytical and empirical basis for this argument. The difficulty in testing the assumption that work leads to a change in beliefs is that

  4. Finding Jobs: Work and Welfare Reform.

    ERIC Educational Resources Information Center

    Card, David E., Ed.; Blank, Rebecca M., Ed.

    This book contains 13 papers on labor market and welfare reform, with special emphasis on the demand for low-wage workers, wages and job characteristics in the less skilled labor market, public politics to increase employment and earnings of less skilled workers, and the impact of welfare reform. The following papers are included: "The Labor…

  5. Reconsidering Schools and the American Welfare State

    ERIC Educational Resources Information Center

    Cohen, Miriam

    2005-01-01

    In this article, the author discusses her comparative study of the history of the welfare state in the United States, England, and France, she studies some of the usual features of the welfare state, which include important entitlement programs, such as social insurance, and protective labor legislation, but she also focuses on the development of

  6. Hen Welfare in Different Housing Systems

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Egg production systems have become subject to heightened levels of scrutiny due to animal welfare concerns. Multiple factors such as disease, skeletal and foot health, pest and parasite load, behavior, stress, affective states, nutrition, and genetics influence the level of welfare laying hens exper...

  7. Animal Welfare: What's coming down the pipe?

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Concern for farm animal welfare is not a new concept. However, increased public pressure and an increasingly entangled global economy are effecting change across the world. The conversation about farm animal welfare is difficult because the world’s population has become disconnected from agricultur...

  8. Bioethical Problems: Animal Welfare, Animal Rights.

    ERIC Educational Resources Information Center

    March, B. E.

    1984-01-01

    Discusses various bioethical issues and problems related to animal welfare and animal rights. Areas examined include: Aristotelian views; animal welfare legislation; Darwin and evolutionary theory; animal and human behavior; and vegetarianism. A 14-point universal declaration of the rights of animals is included. (JN)

  9. Indian Child Welfare Program. Program Documentation.

    ERIC Educational Resources Information Center

    Harris, Francis

    The Indian Child Welfare Program (ICWP), sponsored by the Jewish Family and Children's Service of Phoenix and funded by the Bureau of Indian Affairs, is the nation's first program to provide comprehensive child welfare services to Indian people both on and off the reservation. Beginning in 1973 as an Indian Adoption Project to prevent the

  10. The Role of the Welfare Advocate.

    ERIC Educational Resources Information Center

    Jermany, Catherine Day

    The paper, part of the paralegal training materials prepared by the National Paralegal Institution, discusses the role of the welfare advocate, a type of legal assistant: the right and responsibility to refuse a case; competency to provide adequate representation; informal advocacy vs. formal advocacy in welfare; arranging the negotiation setting…

  11. Does the Minimum Wage Affect Welfare Caseloads?

    ERIC Educational Resources Information Center

    Page, Marianne E.; Spetz, Joanne; Millar, Jane

    2005-01-01

    Although minimum wages are advocated as a policy that will help the poor, few studies have examined their effect on poor families. This paper uses variation in minimum wages across states and over time to estimate the impact of minimum wage legislation on welfare caseloads. We find that the elasticity of the welfare caseload with respect to the…

  12. Effects of Welfare Participation on Marriage

    ERIC Educational Resources Information Center

    Teitler, Julien O.; Reichman, Nancy E.; Nepomnyaschy, Lenna; Garfinkel, Irwin

    2009-01-01

    We investigated the widely held premise that welfare participation causes women to refrain from marriage. Using data from the Fragile Families and Child Wellbeing Study (N = 3,219), we employed an event history approach to study transitions to marriage among mothers who have had a nonmarital birth. We found that welfare participation reduces the…

  13. Assessment of positive welfare: a review.

    PubMed

    Yeates, J W; Main, D C J

    2008-03-01

    As a complement to the concentration on negative states in welfare science, scientists are increasingly considering the desirability of measuring positive outcomes. Since evaluation of an animal's mental state is a critical goal for welfare assessment, considerations of both positive feelings (what an animal "likes") and resources that an animal is motivated to obtain (what an animal "wants") appear to be important. However, since animals may make choices that are not in their long-term interests, an assessment of positive feelings and resources should include an evaluation of any associated actual or potential harms, such as fear, distress, pain, injury and disease. A review of current evidence suggests that positive welfare can be best assessed by evaluation of resources (i.e. inputs) that are valued by an animal and by positive outcomes such as behavioural responses, influences on cognitive processes and physiological markers. Since negative welfare is often inversely correlated with positive welfare measures, current welfare policy will have been achieving some positive welfare outcomes, however the explicit inclusion of positive welfare outcomes in the framework allows for analyses that are both deeper and more in tune with commonsense, which can hopefully yield more objective policies. PMID:17613265

  14. Effects of Welfare Participation on Marriage

    ERIC Educational Resources Information Center

    Teitler, Julien O.; Reichman, Nancy E.; Nepomnyaschy, Lenna; Garfinkel, Irwin

    2009-01-01

    We investigated the widely held premise that welfare participation causes women to refrain from marriage. Using data from the Fragile Families and Child Wellbeing Study (N = 3,219), we employed an event history approach to study transitions to marriage among mothers who have had a nonmarital birth. We found that welfare participation reduces the

  15. Child Welfare in 25 States: An Overview.

    ERIC Educational Resources Information Center

    National Center for Child Advocacy (DHEW/OHD), Washington, DC.

    This overview presents a summary of the major findings of a 25-state survey of child welfare service delivery systems, as studied by Peat, Marwick, Mitchell & Co. in association with the Child Welfare League of America (CWLA) during the period of November 1975 through February 1976. The initial products of the survey were 25 state profiles; these…

  16. Phantom Welfare: Public Relief for Corporate America.

    ERIC Educational Resources Information Center

    Huff, Daniel D.; Johnson, David A.

    1993-01-01

    Describes and quantifies major types of federal subsidies to American businesses, calling subsidies important policies that directly affect more traditional welfare programs. Notes that policies responsible for "phantom welfare state" represent major redistribution of wealth that partially accounts for growing gap between rich and poor. Discusses

  17. The globalisation of farm animal welfare.

    PubMed

    Fraser, D

    2014-04-01

    Animal welfare has achieved significant global prominence for perhaps three reasons. First, several centuries of scientific research, especially in anatomy, evolutionary biology and animal behaviour, have led to a gradual narrowing of the gap that people perceive between humans and other species; this altered perception has prompted grass-roots attention to animals and their welfare, initially in Western countries but now more globally asthe influence of science has expanded. Second, scientific research on animal welfare has provided insights and methods for improving the handling, housing and management of animals; this 'animal welfare science' is increasingly seen as relevant to improving animal husbandry worldwide. Third, the development and use of explicit animal welfare standards has helped to integrate animal welfare as a component of national and international public policy, commerce and trade. To date, social debate about animal welfare has been dominated bythe industrialised nations. However, as the issue becomes increasingly global, it will be important for the non-industrialised countries to develop locally appropriate approaches to improving animal welfare, for example, by facilitating the provision of shelter, food, water and health care, and by improving basic handling, transportation and slaughter. PMID:25000775

  18. Child Welfare Worker Caseload: What's Just Right?

    ERIC Educational Resources Information Center

    Yamatani, Hide; Engel, Rafael; Spjeldnes, Solveig

    2009-01-01

    This study was designed to establish a caseload standard for child welfare workers. Understanding reasonable workload expectations for child welfare workers is a cornerstone of quality service provision and the recruitment and retention of qualified workers. Because of the analytic complexity of this question, qualitative and quantitative methods…

  19. AID and the Single Welfare Mother.

    ERIC Educational Resources Information Center

    Ooms, Theodora; Steinfels, Margaret O'Brien

    1983-01-01

    Debates the issue of voluntary artificial insemination among single women who depend on public assistance. Ooms argues that eligibility for welfare should be based on court defined criteria rather than on moral judgments, while Steinfels suggests that the welfare of the child is most important in any consideration. (Author/AOS)

  20. Coordinating Welfare and Substance Abuse Services.

    ERIC Educational Resources Information Center

    Kaplan, Jan

    2002-01-01

    State welfare agencies increasingly face the challenge of serving a caseload with multiple barriers to employment. For example, a significant proportion of clients may have substance abuse problems that hamper their ability to participate in required activities and move toward self-sufficiency. Coordinating and integrating welfare and substance…

  1. Finding Jobs: Work and Welfare Reform.

    ERIC Educational Resources Information Center

    Card, David E., Ed.; Blank, Rebecca M., Ed.

    This book contains 13 papers on labor market and welfare reform, with special emphasis on the demand for low-wage workers, wages and job characteristics in the less skilled labor market, public politics to increase employment and earnings of less skilled workers, and the impact of welfare reform. The following papers are included: "The Labor

  2. The Climate of Child Welfare Employee Retention

    ERIC Educational Resources Information Center

    Cahalane, Helen; Sites, Edward W.

    2008-01-01

    This article describes differences in perceptions of the child welfare work environment among Title IV-E educated individuals who remain within public child welfare and those who sought employment elsewhere after fulfilling a legal work commitment. Job satisfaction, emotional exhaustion, and personal accomplishment were predictive of staying…

  3. Climb On! From Welfare to a Degree.

    ERIC Educational Resources Information Center

    Christensen, Patti; Kime, Bruce

    In operation since 1990, the Gateway Program is a collaborative welfare reform effort developed by Colorado Mountain College (CMC), the county department of social services, and the local Job Training Partnership Act provider. One component of the program is the Link Program, developed to prepare welfare recipients for enrollment in vocational

  4. Child Welfare Worker Caseload: What's Just Right?

    ERIC Educational Resources Information Center

    Yamatani, Hide; Engel, Rafael; Spjeldnes, Solveig

    2009-01-01

    This study was designed to establish a caseload standard for child welfare workers. Understanding reasonable workload expectations for child welfare workers is a cornerstone of quality service provision and the recruitment and retention of qualified workers. Because of the analytic complexity of this question, qualitative and quantitative methods

  5. Integration into the Social Demographic Welfare State

    ERIC Educational Resources Information Center

    Hjerm, Mikael

    2005-01-01

    This article examines the assumption that the social democratic welfare state is better than others in integrating immigrants into society, or at least that the comprehensive welfare state should compensate for the problems of labour market entry. A number of key indicators from The Living Conditions Survey are used to show that this assumption is

  6. Mechanisms of Chromosomal Instability

    PubMed Central

    Thompson, Sarah L.; Bakhoum, Samuel F.; Compton, Duane A.

    2013-01-01

    Most solid tumors are aneuploid, having a chromosome number that is not a multiple of the haploid number, and many frequently mis-segregate whole chromosomes in a phenomenon called chromosomal instability (CIN). CIN positively correlates with poor patient prognosis, indicating that reduced mitotic fidelity contributes to cancer progression by increasing genetic diversity among tumor cells. Here, we review the mechanisms underlying CIN, which include defects in chromosome cohesion, mitotic checkpoint function, centrosome copy number, kinetochore–microtubule attachment dynamics, and cell-cycle regulation. Understanding these mechanisms provides insight into the cellular consequences of CIN and reveals the possibility of exploiting CIN in cancer therapy. PMID:20334839

  7. Building mitotic chromosomes

    PubMed Central

    Ohta, Shinya; Wood, Laura; Bukowski-Wills, Jimi-Carlo; Rappsilber, Juri; Earnshaw, William C

    2011-01-01

    Mitotic chromosomes are the iconic structures into which the genome is packaged to ensure its accurate segregation during mitosis. Although they have appeared on countless journal cover illustrations, there remains no consensus on how the chromatin fiber is packaged during mitosis. In fact, work in recent years has both added to existing controversies and sparked new ones. By contrast, there has been very significant progress in determining the protein composition of isolated mitotic chromosomes. Here, we discuss recent studies of chromosome organization and provide an in depth description of the latest proteomics studies, which have at last provided us with a definitive proteome for vertebrate chromosomes. PMID:20974528

  8. The context of child welfare performance measures.

    PubMed

    Carnochan, Sarah; Samples, Mark; Lawson, Jennifer; Austin, Michael J

    2013-01-01

    A growing movement in the United States seeks to improve the outcomes achieved by public agencies through performance measurement strategies. In child welfare policy, a federally mandated performance measurement system has evolved since the 1980s, establishing the federal Child and Family Services Review which uses a series of performance indicators for evaluating the child welfare system. This article reviews the literature on performance measurement and performance management in the public sector in order to develop a conceptual framework for examining the federal child welfare performance measurement system. It briefly summarizes the evolution of federal policy related to performance measurement in child welfare. The framework is then used to guide an analysis of the debate surrounding the establishment of the current child welfare performance measurement system, concluding with recommendations for consideration in future reform efforts. PMID:23705647

  9. Welfare dynamics, support services, mothers' earnings, and child cognitive development: implications for contemporary welfare reform.

    PubMed

    Yoshikawa, H

    1999-01-01

    This prospective longitudinal study, using data from the National Longitudinal Survey of Youth (NLSY; N = 614), addresses the gap in the research literature regarding the effects of welfare reform on children. Key questions addressed include whether welfare dynamics and support services relevant to welfare reform, both measured across the first 5 years of life, are associated with mothers' earnings in the 6th year and three child cognitive outcomes in the 7th and 8th years: Peabody Individual Achievement Test (PIAT) math and reading scores, and the Peabody Picture Vocabulary Test (PPVT). Welfare dynamics are represented by total time on welfare, degree of cycling on and off welfare, and degree to which welfare and work are combined. Support services measured include three forms of child care (relative, babysitter, and center-based), as well as three forms of human capital supports (child support, job training, and education). Controlling for a range of background factors and for different patterns of welfare use across the first 5 years, small positive associations with mother's earnings were found for child support, education, and job training. Small positive associations also were found between child support and both math and reading scores. Finally positive associations of medium effect size were found between center care and both mothers' earnings and child PPVT scores. Although effect sizes are generally small, the results suggest the potential value of welfare reform approaches that emphasize long-term human capital development. Interactions between welfare dynamics and support services suggest subgroup differences. Specifically, positive effects of support services on earnings are strongest among mothers with higher levels of human capital (higher levels of work while on welfare, lower total time on welfare). Babysitter care appears to have negative effects on both reading and math scores of children whose mothers report low levels of work while on welfare. Implications for welfare reform policy are discussed. PMID:10368922

  10. Chromosomal differentiation of cells

    SciTech Connect

    1993-12-31

    Chapter 16, discusses the chromosomal differentiation of cells. The chromosomes of differentiated cells have been much less studies than those of meristematic or germline cells, probably because such cells do not usually divide spontaneously. However, in many cases they can be induced to undergo mitosis. 26 refs., 2 figs.

  11. Aquatic Equipment Information.

    ERIC Educational Resources Information Center

    Sova, Ruth

    Equipment usually used in water exercise programs is designed for variety, intensity, and program necessity. This guide discusses aquatic equipment under the following headings: (1) equipment design; (2) equipment principles; (3) precautions and contraindications; (4) population contraindications; and (5) choosing equipment. Equipment is used…

  12. Chromosome-specific DNA Repeat Probes

    PubMed Central

    Baumgartner, Adolf; Weier, Jingly Fung; Weier, Heinz-Ulrich G.

    2006-01-01

    In research as well as in clinical applications, fluorescence in situ hybridization (FISH) has gained increasing popularity as a highly sensitive technique to study cytogenetic changes. Today, hundreds of commercially available DNA probes serve the basic needs of the biomedical research community. Widespread applications, however, are often limited by the lack of appropriately labeled, specific nucleic acid probes. We describe two approaches for an expeditious preparation of chromosome-specific DNAs and the subsequent probe labeling with reporter molecules of choice. The described techniques allow the preparation of highly specific DNA repeat probes suitable for enumeration of chromosomes in interphase cell nuclei or tissue sections. In addition, there is no need for chromosome enrichment by flow cytometry and sorting or molecular cloning. Our PCR-based method uses either bacterial artificial chromosomes or human genomic DNA as templates with α-satellite-specific primers. Here we demonstrate the production of fluorochrome-labeled DNA repeat probes specific for human chromosomes 17 and 18 in just a few days without the need for highly specialized equipment and without the limitation to only a few fluorochrome labels. PMID:16924124

  13. Chromosome-specific DNA Repeat Probes

    SciTech Connect

    Baumgartner, Adolf; Weier, Jingly Fung; Weier, Heinz-Ulrich G.

    2006-03-16

    In research as well as in clinical applications, fluorescence in situ hybridization (FISH) has gained increasing popularity as a highly sensitive technique to study cytogenetic changes. Today, hundreds of commercially available DNA probes serve the basic needs of the biomedical research community. Widespread applications, however, are often limited by the lack of appropriately labeled, specific nucleic acid probes. We describe two approaches for an expeditious preparation of chromosome-specific DNAs and the subsequent probe labeling with reporter molecules of choice. The described techniques allow the preparation of highly specific DNA repeat probes suitable for enumeration of chromosomes in interphase cell nuclei or tissue sections. In addition, there is no need for chromosome enrichment by flow cytometry and sorting or molecular cloning. Our PCR-based method uses either bacterial artificial chromosomes or human genomic DNA as templates with {alpha}-satellite-specific primers. Here we demonstrate the production of fluorochrome-labeled DNA repeat probes specific for human chromosomes 17 and 18 in just a few days without the need for highly specialized equipment and without the limitation to only a few fluorochrome labels.

  14. Capturing Chromosome Conformation

    NASA Astrophysics Data System (ADS)

    Dekker, Job; Rippe, Karsten; Dekker, Martijn; Kleckner, Nancy

    2002-02-01

    We describe an approach to detect the frequency of interaction between any two genomic loci. Generation of a matrix of interaction frequencies between sites on the same or different chromosomes reveals their relative spatial disposition and provides information about the physical properties of the chromatin fiber. This methodology can be applied to the spatial organization of entire genomes in organisms from bacteria to human. Using the yeast Saccharomyces cerevisiae, we could confirm known qualitative features of chromosome organization within the nucleus and dynamic changes in that organization during meiosis. We also analyzed yeast chromosome III at the G1 stage of the cell cycle. We found that chromatin is highly flexible throughout. Furthermore, functionally distinct AT- and GC-rich domains were found to exhibit different conformations, and a population-average 3D model of chromosome III could be determined. Chromosome III emerges as a contorted ring.

  15. Animal behavior and animal welfare.

    PubMed

    Houpt, K A

    1991-04-15

    The value of behavioral techniques in assessing animal welfare, and in particular assessing the psychological well being of animals, is reviewed. Using cats and horses as examples, 3 behavioral methods are presented: (1) comparison of behavior patterns and time budgets; (2) choice tests; and (3) operant conditioning. The behaviors of intact and declawed cats were compared in order to determine if declawing led to behavioral problems or to a change in personality. Apparently it did not. The behavior of free ranging horses was compared with that of stabled horses. Using two-choice preference tests, the preference of horses for visual contact with other horses and the preference for bedding were determined. Horses show no significant preference for locations from which they can make visual contact with other horses, but they do prefer bedding, especially when lying down. Horses will perform an operant response in order to obtain light in a darkened barn or heat in an outside shed. These same techniques can be used to answer a variety of questions about an animal's motivation for a particular attribute of its environment. PMID:2061151

  16. Welfare monitoring schemes: using research to safeguard welfare of animals on the farm.

    PubMed

    Barnett, John L; Hemsworth, Paul H

    2009-01-01

    There are a number of nonhuman animal welfare monitoring schemes for animals on the farm in Australia and in other countries. Although the majority of such schemes are voluntary rather than legislated, some are nevertheless enforced through a number of customer requirements that industries must meet to gain access to markets. Animal welfare monitoring schemes rely on a number of measures, but the majority are based on simple measures of resource or management inputs with fewer animal-based measures; few are specific to animal welfare outcomes. Furthermore, most measures are used retrospectively, particularly where there has been a problem, to improve welfare for the next "batch" of animals and thus few measures can be used to predict animal welfare outcomes with these schemes. There is considerable uncertainty about the concept and consequently the measurement of animal welfare. Science has a clear contribution to make in forging better agreement on animal welfare assessment and also has important roles in both developing practical animal-based measures of animal welfare and validating that animal welfare monitoring schemes are worthwhile in improving at least some aspects of animal welfare. PMID:19319714

  17. Behavior analysis and farm animal welfare

    PubMed Central

    Foster, T. Mary; Temple, William; Poling, Alan

    1997-01-01

    This article demonstrates that there is a role for behavior-analytic techniques in the area of farm animal welfare and provides examples of the kinds of work that can be done. Behavior-analytic procedures, specifically those used in the study of psychophysics, preference, and demand, can provide answers to three questions people concerned with the welfare of farm animals are likely to ask: What can the animals detect? What do they like and dislike? What will they work to attain or preserve? Such information certainly is necessary for making reasonable decisions about animal welfare, although it is not sufficient in and of itself. PMID:22478283

  18. Assessment of welfare of Brazilian and Belgian broiler flocks using the Welfare Quality protocol.

    PubMed

    Tuyttens, F A M; Federici, J F; Vanderhasselt, R F; Goethals, K; Duchateau, L; Sans, E C O; Molento, C F M

    2015-08-01

    The Welfare Quality consortium has proposed a science-based protocol for assessing broiler chicken welfare on farms. Innovative features make the protocols particularly suited for comparative studies, such as the focus on animal-based welfare measures and an integration procedure for calculating an overall welfare status. These protocols reflect the scientific status up to 2009 but are meant to be updated on the basis of inter alia implementation studies. Because only few such studies have been done, we applied the Welfare Quality protocol to compare the welfare of broiler flocks in Belgium (representing a typical European Union (EU) country which implies stringent animal welfare legislation) versus Brazil (the major broiler meat exporter to the EU and with minimal animal welfare legislation). Two trained observers performed broiler Welfare Quality assessments on a total of 22 farms in Belgium and south Brazil. All of the farms produced for the EU market. Although the overall welfare was categorized as 'acceptable' on all farms, many country differences were observed at the level of the welfare principles, criteria, and measures. Brazilian farms obtained higher scores for 3 of the 4 welfare principles: 'good feeding' (P=0.007), 'good housing' (P<0.001), and 'good health' (P=0.005). Four of the 10 welfare criteria scores were, or tended to be, higher on Brazilian than Belgian farms: 'absence of prolonged thirst' (P<0.001), 'ease of movement' (P<0.001), 'absence of injuries' (P=0.002), and 'positive emotional state' (P=0.055). The only criteria with a higher score for the Belgian farms than their Brazilian counterparts were 'absence of prolonged hunger' (P=0.048) and 'good human-animal relationship' (P=0.002). Application of the Welfare Quality protocol has raised several concerns about the validity, reliability, and discriminatory potential of the protocol. The results also call for more research into the effect of animal welfare legislation as broiler welfare on the south Brazilian farms appeared to be superior to that on the Belgian farms. Animal-based welfare assessments on a larger sample of farms are needed to evaluate to what extent these findings may be generalized. PMID:26049803

  19. Sequential cloning of chromosomes

    DOEpatents

    Lacks, Sanford A.

    1995-07-18

    A method for sequential cloning of chromosomal DNA of a target organism is disclosed. A first DNA segment homologous to the chromosomal DNA to be sequentially cloned is isolated. The first segment has a first restriction enzyme site on either side. A first vector product is formed by ligating the homologous segment into a suitably designed vector. The first vector product is circularly integrated into the target organism's chromosomal DNA. The resulting integrated chromosomal DNA segment includes the homologous DNA segment at either end of the integrated vector segment. The integrated chromosomal DNA is cleaved with a second restriction enzyme and ligated to form a vector-containing plasmid, which is replicated in a host organism. The replicated plasmid is then cleaved with the first restriction enzyme. Next, a DNA segment containing the vector and a segment of DNA homologous to a distal portion of the previously isolated DNA segment is isolated. This segment is then ligated to form a plasmid which is replicated within a suitable host. This plasmid is then circularly integrated into the target chromosomal DNA. The chromosomal DNA containing the circularly integrated vector is treated with a third, retrorestriction (class IIS) enzyme. The cleaved DNA is ligated to give a plasmid that is used to transform a host permissive for replication of its vector. The sequential cloning process continues by repeated cycles of circular integration and excision. The excision is carried out alternately with the second and third enzymes.

  20. Sequential cloning of chromosomes

    DOEpatents

    Lacks, S.A.

    1995-07-18

    A method for sequential cloning of chromosomal DNA of a target organism is disclosed. A first DNA segment homologous to the chromosomal DNA to be sequentially cloned is isolated. The first segment has a first restriction enzyme site on either side. A first vector product is formed by ligating the homologous segment into a suitably designed vector. The first vector product is circularly integrated into the target organism`s chromosomal DNA. The resulting integrated chromosomal DNA segment includes the homologous DNA segment at either end of the integrated vector segment. The integrated chromosomal DNA is cleaved with a second restriction enzyme and ligated to form a vector-containing plasmid, which is replicated in a host organism. The replicated plasmid is then cleaved with the first restriction enzyme. Next, a DNA segment containing the vector and a segment of DNA homologous to a distal portion of the previously isolated DNA segment is isolated. This segment is then ligated to form a plasmid which is replicated within a suitable host. This plasmid is then circularly integrated into the target chromosomal DNA. The chromosomal DNA containing the circularly integrated vector is treated with a third, retrorestriction (class IIS) enzyme. The cleaved DNA is ligated to give a plasmid that is used to transform a host permissive for replication of its vector. The sequential cloning process continues by repeated cycles of circular integration and excision. The excision is carried out alternately with the second and third enzymes. 9 figs.

  1. Sequential cloning of chromosomes

    SciTech Connect

    Lacks, S.A.

    1991-12-31

    A method for sequential cloning of chromosomal DNA and chromosomal DNA cloned by this method are disclosed. The method includes the selection of a target organism having a segment of chromosomal DNA to be sequentially cloned. A first DNA segment, having a first restriction enzyme site on either side. homologous to the chromosomal DNA to be sequentially cloned is isolated. A first vector product is formed by ligating the homologous segment into a suitably designed vector. The first vector product is circularly integrated into the target organism`s chromosomal DNA. The resulting integrated chromosomal DNA segment includes the homologous DNA segment at either end of the integrated vector segment. The integrated chromosomal DNA is cleaved with a second restriction enzyme and ligated to form a vector-containing plasmid, which is replicated in a host organism. The replicated plasmid is then cleaved with the first restriction enzyme. Next, a DNA segment containing the vector and a segment of DNA homologous to a distal portion of the previously isolated DNA segment is isolated. This segment is then ligated to form a plasmid which is replicated within a suitable host. This plasmid is then circularly integrated into the target chromosomal DNA. The chromosomal DNA containing the circularly integrated vector is treated with a third, retrorestriction enzyme. The cleaved DNA is ligated to give a plasmid that is used to transform a host permissive for replication of its vector. The sequential cloning process continues by repeated cycles of circular integration and excision. The excision is carried out alternately with the second and third enzymes.

  2. [Ethological approaches concerning forensic animal welfare].

    PubMed

    Zeeb, K

    1996-11-01

    Two cases of jurisdiction lay open the practicability of ethological approaches as to answer forensical questions of animal welfare. Two concepts were presented: The concept of satisfaction of requirements and a new concept for the assessment of feelings. PMID:9081822

  3. The Child Welfare Agency as School Consultant

    ERIC Educational Resources Information Center

    Schild, Judith S.; And Others

    1976-01-01

    Describes the School Consultation Program offered by the Jewish Children's Bureau (JCB) to the special education personnel of four elementary schools in a suburban school district. Discusses problems and special techniques of applying child welfare to school consultation. (JH)

  4. Health insurance: an eye on American welfare.

    PubMed

    Draper, J

    1980-02-15

    One of the great myths about the United States is that it does not have a welfare state. The myth is largely founded on the fact that America is one of the few remaining western nations with no national health insurance scheme to protect its citizens against the crippling costs of medical and hospital care. However, that does not mean that the United States does not have an extensive welfare system, writes John Draper. PMID:10245813

  5. Welfare reform and parenting: reasonable expectations.

    PubMed

    Chase-Lansdale, P Lindsay; Pittman, Laura D

    2002-01-01

    Although the primary goals of federal welfare reform legislation were to move welfare mothers into the workforce and reduce births outside of marriage, promotion of responsible parenting was also an important underlying theme. Parenting is a complex, multifaceted phenomenon, however, encompassing a wide range of functions related to nurturing, discipline, stimulation, values, activities, and routines. This article provides a framework for assessing the impact of welfare reform on various dimensions of parenting, with the following key findings: Many aspects of life affect parenting and child development, such as parent characteristics, child characteristics, family economic resources, family structure, parental mental health, marital or partner relationships, and the quality of parents' kin and social networks. About two-thirds of states are using federal welfare funds to promote better parenting through programs such as home visits to new parents and parenting classes, but virtually no state parenting programs have been evaluated. Welfare reform appears to have limited effects on parenting. The only dimension of parenting significantly affected by some welfare demonstration programs was parents' choice of child care settings and extracurricular activities for their children. The programs with the greatest positive impact on parenting were those with more generous work supports and more flexible work requirements. Not only did these programs lead to different choices concerning child care and activities for preschool and school-age children, but they also resulted in more stable marriages and less violence between partners, which also could lead to improved parenting. The authors conclude that many important aspects of the connection between welfare reform and parenting have yet to be examined, and that further research is needed to identify the ways states' welfare programs can promote better parenting. PMID:11980035

  6. A new chromosome was born: comparative chromosome painting in Boechera.

    PubMed

    Koch, Marcus A

    2015-09-01

    Comparative chromosome painting is a powerful tool to study the evolution of chromosomes and genomes. Analyzing karyotype evolution in cruciferous plants highlights the origin of aberrant chromosomes in apomictic Boechera and further establishes the cruciferous plants as important model system for our understanding of plant chromosome and genome evolution. PMID:26228436

  7. Animal welfare: an animal science approach.

    PubMed

    Koknaroglu, H; Akunal, T

    2013-12-01

    Increasing world population and demand for animal-derived protein puts pressure on animal production to meet this demand. For this purpose animal breeding efforts were conducted to obtain the maximum yield that the genetic makeup of the animals permits. Under the influence of economics which is the driving force behind animal production, animal farming became more concentrated and controlled which resulted in rearing animals under confinement. Since more attention was given on economics and yield per animal, animal welfare and behavior were neglected. Animal welfare which can be defined as providing environmental conditions in which animals can display all their natural behaviors in nature started gaining importance in recent years. This does not necessarily mean that animals provided with good management practices would have better welfare conditions as some animals may be distressed even though they are in good environmental conditions. Consumers are willing to pay more for welfare-friendly products (e.g.: free range vs caged egg) and this will change the animal production practices in the future. Thus animal scientists will have to adapt themselves for the changing animal welfare rules and regulations that differ for farm animal species and countries. In this review paper, animal welfare is discussed from an animal science standpoint. PMID:23664009

  8. Drivers for animal welfare policies in Africa.

    PubMed

    Molomo, M; Mumba, T

    2014-04-01

    Livestock in Africa represent on average 30% of the agricultural gross domestic product (GDP) and about 10% of the national GDP. Up to 300 million people depend on livestock for their income and livelihood. Accordingly, livestock are considered to be important for the African continent. Despite this, little or no provision for animal welfare is made in the laws and regulations of most African countries. However, the World Organisation for Animal Health (OIE) Performance of Veterinary Services (PVS) Tool includes animal welfare as a critical competency in Veterinary Services, and most African countries have now conducted PVS appraisals. The development of a Regional Animal Welfare Strategy in Africa is also important because it will provide opportunities for full engagement by all relevant parties. Key elements in this process should include collaboration and coordination in information dissemination to all stakeholders, who should include all those in the value chain. The roles played by the OIE Member Delegates and Focal Points, and non-governmental organisations (NGOs), in driving animal welfare policy in most African countries are notable. Without a level of understanding of animal welfare that is sufficient to support clear animal welfare policy development and implementation, problems may appear in the near future which could jeopardise the attainment of increased animal productivity and product quality. This may have negative implications for economic growth and for national and international trade. PMID:25000777

  9. [Epilepsy in chromosome aberrations].

    PubMed

    Bahi-Buisson, N; Ville, D; Eisermann, M; Plouin, P; Kaminska, A; Chiron, C

    2005-04-01

    Epilepsy is among the most frequent finding in many chromosome aberrations. While most chromosome aberrations can be associated with different seizure types, there are few aberrations which feature specific seizures and EEG patterns. Among the 400 different chromosomal imbalances described with seizures and EEG abnormalities, eight have a high association with epilepsy. These comprise: the monosomy 1p36, Wolf-Hirschhorn syndrome (4p-), Angelman syndrome, Miller-Dieker del 17p13.3, the inversion duplication 15 syndrome, ring 20 and ring 14 syndromes, Down's syndrome. These chromosomal regions where aberrations have an evident association with epilepsy may be useful targets for gene hunters. On the other hand, a better characterisation of epileptic syndrome in these disorders may lead to a better and specific treatment. PMID:15808438

  10. [Chromosomal changes in cancers].

    PubMed

    Sakaki, M S

    1984-04-01

    In addition to the chromosome changes common to cancers, recent development of cytogenetics in human cancers has revealed, the site of specific chromosome changes which characterize specific cancers. Such cancer-specific aberrations are generally reciprocal translocations or deletions, and in some cases the translocations have been unequivocally demonstrated to involve cellular oncogenes (c-onc) in the new transcriptional control of other genes. Chromosome changes relatively common to cancers are amplification of specific genes by chromosome duplication or selective amplification as manifested by double minutes or homogeneously staining regions, and genome reorganization by nondisjunction, somatic recombination, polyploidization-segregation or other parasexual recombinations. The importance of such genome reorganization in cancer development was discussed in relation to the possible involvement of cellular escape mechanisms. PMID:6372697

  11. Levers for Change: Educational Opportunity Center's and Welfare Reform.

    ERIC Educational Resources Information Center

    Dann-Messier, Brenda

    2001-01-01

    Asserts the importance of changing welfare policies to allow postsecondary education as a work activity. Discusses the history of welfare reform and the benefits of postsecondary education for welfare recipients; describes services provided to welfare recipients by several TRIO-sponsored Educational Opportunity Centers (EOCs); and offers…

  12. Longitudinal Effects of Domestic Violence on Employment and Welfare Outcomes

    ERIC Educational Resources Information Center

    Lindhorst, Taryn; Oxford, Monica; Gillmore, Mary Rogers

    2007-01-01

    This study uses longitudinal data spanning 13 years from a study of 234 adolescent mothers to evaluate the effects of cumulative domestic violence on employment and welfare use before and after welfare reform. Domestic violence increased the odds of unemployment after welfare reform, but not before; domestic violence had no effect on welfare use

  13. Effects of Welfare Reform on Vocational Education and Training

    ERIC Educational Resources Information Center

    Dave, Dhaval M.; Reichman, Nancy E.; Corman, Hope; Das, Dhiman

    2011-01-01

    Exploiting variation in welfare reform across states and over time and using relevant comparison groups, this study estimates the effects of welfare reform on an important source of human capital acquisition among women at risk for relying on welfare: vocational education and training. The results suggest that welfare reform reduced enrollment in…

  14. Effects of Welfare Reform on Vocational Education and Training

    ERIC Educational Resources Information Center

    Dave, Dhaval M.; Reichman, Nancy E.; Corman, Hope; Das, Dhiman

    2011-01-01

    Exploiting variation in welfare reform across states and over time and using relevant comparison groups, this study estimates the effects of welfare reform on an important source of human capital acquisition among women at risk for relying on welfare: vocational education and training. The results suggest that welfare reform reduced enrollment in

  15. A Look at Child Welfare from a Homeless Education Perspective

    ERIC Educational Resources Information Center

    National Center for Homeless Education at SERVE, 2007

    2007-01-01

    Although navigating the child welfare system can be daunting for those working in the field of homeless education, local liaisons and others must determine whether children in the child welfare system are eligible for McKinney-Vento services and collaborate with child welfare staff. This document provides an overview of the U.S. child welfare

  16. 43 CFR 17.250 - Health, welfare, and social services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Health, welfare, and social services. 17... § 17.250 Health, welfare, and social services. This subpart applies to health, welfare, and other...) General. In providing health, welfare, or other social services or benefits, a recipient may not, on...

  17. Longitudinal Effects of Domestic Violence on Employment and Welfare Outcomes

    ERIC Educational Resources Information Center

    Lindhorst, Taryn; Oxford, Monica; Gillmore, Mary Rogers

    2007-01-01

    This study uses longitudinal data spanning 13 years from a study of 234 adolescent mothers to evaluate the effects of cumulative domestic violence on employment and welfare use before and after welfare reform. Domestic violence increased the odds of unemployment after welfare reform, but not before; domestic violence had no effect on welfare use…

  18. 43 CFR 17.250 - Health, welfare, and social services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Health, welfare, and social services. 17... § 17.250 Health, welfare, and social services. This subpart applies to health, welfare, and other...) General. In providing health, welfare, or other social services or benefits, a recipient may not, on...

  19. 43 CFR 17.250 - Health, welfare, and social services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Health, welfare, and social services. 17... § 17.250 Health, welfare, and social services. This subpart applies to health, welfare, and other...) General. In providing health, welfare, or other social services or benefits, a recipient may not, on...

  20. 43 CFR 17.250 - Health, welfare, and social services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Health, welfare, and social services. 17... § 17.250 Health, welfare, and social services. This subpart applies to health, welfare, and other...) General. In providing health, welfare, or other social services or benefits, a recipient may not, on...

  1. Genetic markers on chromosome 7.

    PubMed Central

    Tsui, L C

    1988-01-01

    Chromosome 7 is frequently associated with chromosome aberrations, rearrangements, and deletions. It also contains many important genes, gene families, and disease loci. This brief review attempts to summarise these and other interesting aspects of chromosome 7. With the rapid accumulation of cloned genes and polymorphic DNA fragments, this chromosome has become an excellent substrate for molecular genetic studies. PMID:3290488

  2. Chromosome doubling method

    SciTech Connect

    Kato, Akio

    2006-11-14

    The invention provides methods for chromosome doubling in plants. The technique overcomes the low yields of doubled progeny associated with the use of prior techniques for doubling chromosomes in plants such as grasses. The technique can be used in large scale applications and has been demonstrated to be highly effective in maize. Following treatment in accordance with the invention, plants remain amenable to self fertilization, thereby allowing the efficient isolation of doubled progeny plants.

  3. Pure chromosome-specific PCR libraries from single sorted chromosomes.

    PubMed Central

    VanDevanter, D R; Choongkittaworn, N M; Dyer, K A; Aten, J; Otto, P; Behler, C; Bryant, E M; Rabinovitch, P S

    1994-01-01

    Chromosome-specific DNA libraries can be very useful in molecular and cytogenetic genome mapping studies. We have developed a rapid and simple method for the generation of chromosome-specific DNA sequences that relies on polymerase chain reaction (PCR) amplification of a single flow-sorted chromosome or chromosome fragment. Previously reported methods for the development of chromosome libraries require larger numbers of chromosomes, with preparation of pure chromosomes sorted by flow cytometry, generation of somatic cell hybrids containing targeted chromosomes, or a combination of both procedures. These procedures are labor intensive, especially when hybrid cell lines are not already available, and this has limited the generation of chromosome-specific DNA libraries from nonhuman species. In contrast, a single sorted chromosome is a pure source of DNA for library production even when flow cytometric resolution of chromosome populations is poor. Furthermore, any sorting cytometer may be used with this technique. Using this approach, we demonstrate the generation of PCR libraries suitable for both molecular and fluorescence in situ hybridization studies from individual baboon and canine chromosomes, separate human homologues, and a rearranged marker chromosome from a transformed cell line. PCR libraries specific to subchromosomal regions have also been produced by sorting a small chromosome fragment. This simple and rapid technique will allow generation of nonhuman linkage maps and probes for fluorescence in situ hybridization and the characterization of marker chromosomes from solid tumors. In addition, allele-specific libraries generated by this strategy may also be useful for mapping genetic diseases. Images PMID:8016078

  4. Welfare state regimes and population health: integrating the East Asian welfare states.

    PubMed

    Abdul Karim, Syahirah; Eikemo, Terje A; Bambra, Clare

    2010-01-01

    Epidemiological studies have consistently shown that population health varies significantly by welfare state regime. However, these studies have focused exclusively on the welfare states of Europe, North America and Australasia. This focus ignores the existence of welfare states in other parts of the world, specifically in East Asia. This study therefore investigates whether the association between population health (Infant Mortality Rates and Life Expectancy at birth) and welfare state regimes is still valid when the welfare states of East Asia are added into the analysis. It also examines whether population health is worse in the East Asian welfare states. Infant Mortality Rates and Life Expectancy at birth as well as GDP per capita and social and health expenditures as a percentage of GDP were examined in 30 welfare states, categorised into six different regimes (Scandinavian, Anglo-Saxon, Bismarckian, Southern, Eastern European and East Asian). ANOVA analysis showed significant differences by welfare state regime in the magnitude of IMR, LE, SE, HE and GDP per capita. However, when controlling for GDP per capita in the ANCOVA analyses, only Life Expectancy (R(2)=0.58, adjusted R(2)=0.47, p<0.05) and Social Expenditure (R(2)=0.70, adjusted R(2)=0.61, p<0.05) differed significantly by welfare state regime. 47% of the variation in Life Expectancy was explained by welfare state regime type. Further, the East Asian welfare states did not have the worst health outcomes. The study concludes by highlighting the need to expand comparative health analysis both in terms of the range of countries examined and also in terms of incorporating other societal and public health factors-towards a 'public health regime' analysis. PMID:19748149

  5. Micromechanics of human mitotic chromosomes

    NASA Astrophysics Data System (ADS)

    Sun, Mingxuan; Kawamura, Ryo; Marko, John F.

    2011-02-01

    Eukaryote cells dramatically reorganize their long chromosomal DNAs to facilitate their physical segregation during mitosis. The internal organization of folded mitotic chromosomes remains a basic mystery of cell biology; its understanding would likely shed light on how chromosomes are separated from one another as well as into chromosome structure between cell divisions. We report biophysical experiments on single mitotic chromosomes from human cells, where we combine micromanipulation, nano-Newton-scale force measurement and biochemical treatments to study chromosome connectivity and topology. Results are in accord with previous experiments on amphibian chromosomes and support the 'chromatin network' model of mitotic chromosome structure. Prospects for studies of chromosome-organizing proteins using siRNA expression knockdowns, as well as for differential studies of chromosomes with and without mutations associated with genetic diseases, are also discussed.

  6. Personal protective equipment

    MedlinePLUS

    Personal protective equipment (PPE) is special equipment you wear to create a barrier between you and germs. ... Centers for Disease Control and Prevention. Personal protective equipment. http://www.cdc.gov/niosh/ppe. Accessed February 20, 2014.

  7. 45 CFR 95.705 - Equipment costs-Federal financial participation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Equipment costs-Federal financial participation... financial participation. (a) General rule. In computing claims for Federal financial participation, equipment having a unit acquisition cost of $25,000 or less may be claimed in the period acquired...

  8. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false State standards for office space, equipment, and... SERVICES GENERAL ADMINISTRATION-PUBLIC ASSISTANCE PROGRAMS § 205.170 State standards for office space... establish and maintain standards for office space, equipment, and facilities that will adequately...

  9. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true State standards for office space, equipment, and... SERVICES GENERAL ADMINISTRATION-PUBLIC ASSISTANCE PROGRAMS § 205.170 State standards for office space... establish and maintain standards for office space, equipment, and facilities that will adequately...

  10. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false State standards for office space, equipment, and... SERVICES GENERAL ADMINISTRATION-PUBLIC ASSISTANCE PROGRAMS § 205.170 State standards for office space... establish and maintain standards for office space, equipment, and facilities that will adequately...

  11. 45 CFR 205.170 - State standards for office space, equipment, and facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false State standards for office space, equipment, and... SERVICES GENERAL ADMINISTRATION-PUBLIC ASSISTANCE PROGRAMS § 205.170 State standards for office space... establish and maintain standards for office space, equipment, and facilities that will adequately...

  12. An Assessment of Social Welfare in Spain: Territorial Analysis Using a Synthetic Welfare Indicator

    ERIC Educational Resources Information Center

    Espina, Pilar Zarzosa; Arechavala, Noelia Somarriba

    2013-01-01

    The aim of this paper is measure social welfare in Spanish provinces. To achieve this, we use the distance method P[subscript 2] to compose a synthetic indicator of welfare for 2007, the last year for which data are available. The index comprises information on different social indicators from various life domains and enables a classification of

  13. On Welfare and Terror: Social Welfare Policies and Political-Economic Roots of Terrorism

    ERIC Educational Resources Information Center

    Burgoon, Brian

    2006-01-01

    This article argues that social welfare policies may reduce international and domestic terrorism. Social policies likely affect terrorism in offsetting ways but, on balance, should diminish preferences for terrorism by reducing economic insecurity, inequality, poverty, and religious-political extremism. Thus, countries with more generous welfare

  14. Methamphetamine and the Changing Face of Child Welfare: Practice Principles for Child Welfare Workers

    ERIC Educational Resources Information Center

    Connell-Carrick, Kelli

    2007-01-01

    Methamphetamine use and production is changing child welfare practice. Methamphetamine is a significant public health threat (National Institute of Justice, 1999) reaching epidemic proportions (Anglin, Burke, Perrochet, Stamper, & Dawud-Nouris, 2000). The manufacturing of methamphetamine is a serious problem for the child welfare system, yet child

  15. Education and Partnerships in Child Welfare: Mapping the Implementation of a Child Welfare Certificate Program

    ERIC Educational Resources Information Center

    Cash, Scottye J.; Mathiesen, Sally G.; Barbanell, Lisa D.; Smith, Thomas E.; Graham, Pamela

    2006-01-01

    This article presents the results of focus groups conducted with participants following the completion of a Child Welfare Practice Certificate Program. Concept mapping was used as the guiding research method for the data collection and analysis. Social work students and child welfare workers generated statements during the focus group session that

  16. Education and Partnerships in Child Welfare: Mapping the Implementation of a Child Welfare Certificate Program

    ERIC Educational Resources Information Center

    Cash, Scottye J.; Mathiesen, Sally G.; Barbanell, Lisa D.; Smith, Thomas E.; Graham, Pamela

    2006-01-01

    This article presents the results of focus groups conducted with participants following the completion of a Child Welfare Practice Certificate Program. Concept mapping was used as the guiding research method for the data collection and analysis. Social work students and child welfare workers generated statements during the focus group session that…

  17. The Role of Education and Training in Welfare Reform. Welfare Reform and Beyond. Policy Brief.

    ERIC Educational Resources Information Center

    Gueron, Judith M.; Hamilton, Gayle

    States have used variants of these three approaches to structure the welfare to-work component of welfare reform for single mothers: (1) put education or training first; (2) place job searching first; and (3) create a flexible program that allows staff and participants choice in the initial and subsequent activities. Research on these program

  18. Experimental studies of welfare reform and children.

    PubMed

    Zaslow, Martha J; Moore, Kristin A; Brooks, Jennifer L; Morris, Pamela A; Tout, Kathryn; Redd, Zakia A; Emig, Carol A

    2002-01-01

    Even prior to passage of federal welfare reform, many demonstration programs anticipated key features of the 1996 law, such as "work-first" strategies, time limits on welfare receipt, and financial incentives to work. Over the past decade, 10 experimental evaluations of these programs have extended their studies to examine the impacts on children. This article provides a synthesis of findings from the first seven of these studies to release results concerning child impacts. Key observations include the following: Across the different types of welfare-to-work programs examined, researchers found neither widespread harm nor widespread benefit to young children, but some significant impacts did occur. Favorable impacts tended to occur in programs that improved family economic status or maternal education, but these programs still did not bring children to the level of national norms for positive child development. Unfavorable impacts tended to occur when families did not show economic progress or when their economic situation worsened, when the children were adolescents, and--unexpectedly--when the families were believed to be at lower risk for long-term welfare receipt. Thus, although impacts were not widespread, these programs did have the potential to affect children for both better and worse across a range of developmental outcomes. The authors conclude that these findings underscore the importance of strengthening program approaches to enhance developmental outcomes for children in families being served by the welfare system. PMID:11980040

  19. Social welfare with a foreign competitor

    NASA Astrophysics Data System (ADS)

    Ferreira, Fernanda A.

    2009-11-01

    In this paper, we consider a mixed market in which a state-owned welfare-maximizing public (domestic) firm competes against a profit-maximizing private (foreign) firm. We suppose that the domestic firm is less efficient than the foreign firm. However, the domestic firm can lower its marginal costs by conducting cost-reducing R&D investment. We examine the impacts of entry of a foreign firm on decisions upon cost-reducing R&D investment by the domestic firm and how these affect the domestic welfare.

  20. A study on laws related to women's welfare.

    PubMed

    Kim, E

    1991-01-01

    Since 1980, the domestic policy of every Korean government has focused on the construction of a welfare society, yet real change remains elusive, leaving women particularly neglected. This study examines social security legislation, especially the laws that define the status and welfare of women with the goal of advancing women's welfare and eliminating sexual discrimination against them. Welfare laws and literature were collected and examined from Korea and aboard, and facilities were visited. This paper reviews: 1) the theoretical background of women's welfare including the feminist critique and strategies for the welfare state and social welfare, and the significance and necessity of women's welfare; 2) women's welfare: international treaties and trends, including the World Declaration of Human Rights, international agreements on human rights, the International Labor Organization Treaty, the UN Convention on the Elimination of Sexual Discrimination Against Women, and the women's development strategies toward the year 2000; 3) the analysis of the laws and regulations related to women's welfare, including the systematic organization of women's welfare law (judicial, and systematic organization by applicable clients), the constitutional basis of the women's welfare related legislation and legal principles, the main feature and problems of the women's welfare related legislation, e.g. the Social Security Act: the National Pensions Act, Medical Insurance Act, the Livelihood Protection Act, Mother-child Welfare Act, Child Welfare Act, the Anti-prostitution Act, and the Gender Equal Employment Act, and 4) the direction of revision of the women's welfare related legislation including the revision and legislation of women's welfare related laws, restructuring of the delivery system, and the formation of proper environment conducive to the realization of women's welfare. PMID:12285932

  1. Phenylbutazone and chromosomal damage.

    PubMed Central

    Walker, S; Price Evans, A; Benn, P A; Littler, T R; Halliday, L D

    1975-01-01

    Investigation of 44 paired test and control patients, all suffering from rheumatoid arthritis, following exposure to phenylbutazone (PBZ) and/or oxyphenbutazone (OPB), suggests that there is no significant increase in the level of chromosomal damage in lymphocytes. The control subjects comprised two series, one previously exposed to PBZ and/or OPB, but not for at least 1-5 years, and the other never exposed to PBZ or OPB. No significant difference in the level of chromosome damage was found between patients never exposed, previously exposed, or now receiving PBZ and/or OPB. PMID:769706

  2. Characterization of chromosomal architecture in Arabidopsis by chromosome conformation capture

    PubMed Central

    2013-01-01

    Background The packaging of long chromatin fibers in the nucleus poses a major challenge, as it must fulfill both physical and functional requirements. Until recently, insights into the chromosomal architecture of plants were mainly provided by cytogenetic studies. Complementary to these analyses, chromosome conformation capture technologies promise to refine and improve our view on chromosomal architecture and to provide a more generalized description of nuclear organization. Results Employing circular chromosome conformation capture, this study describes chromosomal architecture in Arabidopsis nuclei from a genome-wide perspective. Surprisingly, the linear organization of chromosomes is reflected in the genome-wide interactome. In addition, we study the interplay of the interactome and epigenetic marks and report that the heterochromatic knob on the short arm of chromosome 4 maintains a pericentromere-like interaction profile and interactome despite its euchromatic surrounding. Conclusion Despite the extreme condensation that is necessary to pack the chromosomes into the nucleus, the Arabidopsis genome appears to be packed in a predictive manner, according to the following criteria: heterochromatin and euchromatin represent two distinct interactomes; interactions between chromosomes correlate with the linear position on the chromosome arm; and distal chromosome regions have a higher potential to interact with other chromosomes. PMID:24267747

  3. Assessing the Employability of Welfare Clients.

    ERIC Educational Resources Information Center

    Nightingale, Demetra Smith

    This paper describes the client assessment package being used in the Philadelphia Urban Saturation Work Program and discusses some of the issues that should be considered in designing and implementing employability assessment components of welfare-employment programs. The original objectives of the assessment component were the following: (1) to

  4. The View from 1999: A Welfare Fantasy.

    ERIC Educational Resources Information Center

    Olasky, Marvin

    1995-01-01

    This fantasy looks back from 1999 to chronicle the imagined scenario of welfare reform in the presidency of Forrest Gump (and the vice-presidency of William Bennett). The decline in government assistance is matched by an increase in private sources of aid and a heightened sense of personal responsibility among Americans. (SLD)

  5. Adoption and Child Welfare Protection in France

    ERIC Educational Resources Information Center

    Dumaret, Annick-Camille; Rosset, Dominique-Jeanne

    2005-01-01

    This article presents the French Child Protection system, which is managed by Child Welfare of the local authorities (Aide Sociale a l'Enfance) and by Judicial Juvenile Protection depending on the central government (Protection Judiciaire de la Jeunesse) Children's judges are involved in child protection. The majority of children in care live in

  6. Welfare and Support Services for Farm Families.

    ERIC Educational Resources Information Center

    Stayner, Richard; Barclay, Elaine

    Following the extended Australian drought of the 1990s, a review was undertaken to assess the programs and services that support farm families and respond to their welfare needs. A total of 43 service providers and 21 farm families were interviewed in New South Wales and Queensland. Following an introduction and description of methodology, the

  7. Car Ownership and Welfare-to-Work

    ERIC Educational Resources Information Center

    Ong, Paul M.

    2002-01-01

    This study examines the role of car ownership in facilitating employment among recipients under the current welfare-to-work law. Because of a potential problem with simultaneity, the analysis uses predicted car ownership constructed from two instrumental variables, insurance premiums and population density for car ownership. The data come from a

  8. South Dakota Indian Recipients of Public Welfare.

    ERIC Educational Resources Information Center

    South Dakota State Dept. of Public Welfare, Pierre.

    In October of each year, the Research and Statistics Section of the South Dakota Department of Public Welfare studies the racial makeup of its recipients to report on the proportion of American Indians, the state's largest minority group (32,402 or 4.9% of the state's population according to the 1970 census), receiving assistance under state

  9. Global Perspectives on Child Welfare. Preface.

    ERIC Educational Resources Information Center

    Pasztor, Eileen Mayers; McFadden, Emily Jean

    2001-01-01

    Discusses the effects of a global perspective on awareness of issues affecting child welfare worldwide, including warfare, land mines, AIDS, child labor, child sexual exploitation, and immigration. Considers programs and policies from other countries, including nongovernmental organizations, that can be replicated worldwide to better children's…

  10. The use of animal welfare indicators

    Technology Transfer Automated Retrieval System (TEKTRAN)

    At any given time, an animal’s welfare ranges on a scale of very good to very poor. It contains both physical elements and mental elements. The physical elements, such as behaviour, physiology, health, productivity and pathology, can be measured relatively easily, in an experimental setting, but the...

  11. Jobs, Welfare, and Links with Education.

    ERIC Educational Resources Information Center

    Curtis, LeaAnn; Murphrey, Suzanne

    The federally mandated welfare program Jobs Opportunities and Basic Skills (JOBS) was preceded in Kansas by KANWORK, a pilot effort in four counties designed to initiate job preparedness and esteem-building programs. KANWORK, which was to be mandatory for certain public assistance recipients, included education, job skills training, job readiness

  12. Measuring Racial Disparity in Child Welfare

    ERIC Educational Resources Information Center

    Shaw, Terry V.; Putnam-Hornstein, Emily; Magruder, Joseph; Needell, Barbara

    2008-01-01

    Overrepresentation of certain racial/ethnic groups in the foster care system is one of the most troubling and challenging issues in child welfare today. In response, many states have started reporting outcomes by race and ethnicity to identify disproportionately high rates of system contact. The identification of disproportional representation is

  13. SWINE PRODUCTION SYSTEMS: ANIMAL WELFARE CONSIDERATIONS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A general public perception is that it is easy to visualize when an animals welfare is adequate. Scientifically, this determination is quite difficult. The difficulty resides in our ability to objectively assess the animals physical and psychological state; as well as to determine the difference b...

  14. Hen Welfare in Different Housing Systems

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Recently, the public has begun to question the conditions under which intensively-managed livestock are housed. As a consequence of this concern, animal production practices, including egg production systems, have become subject to heightened levels of scrutiny. Animal welfare issues lie at the he...

  15. Welfare and Child Support: Complements, Not Substitutes

    ERIC Educational Resources Information Center

    Cancian, Maria; Meyer, Daniel R.; Caspar, Emma

    2008-01-01

    In most states, child support paid on behalf of Temporary Assistance for Needy Families (TANF) participants is used to offset TANF and child support administrative expenditures; this policy primarily benefits taxpayers. In contrast, Wisconsin allowed most custodial parents to keep all support paid on their behalf. This policy, which treats welfare

  16. STATEWIDE AUTOMATED CHILD WELFARE INFORMATION SYSTEM (SACWIS)

    EPA Science Inventory

    SACWIS stands for Statewide Automated Child Welfare Information System(s). It was authorized by Congress in 1993 to help states meet data collection and reporting requirements of the Social Security Act. The regulations at 45 CFR 1355.50 through 1355.57 provide the basis for Stat...

  17. Welfare Careers and Low Wage Employment.

    ERIC Educational Resources Information Center

    Miller, Joe A.; Ferman, Louis A.

    A sample of 1010 low-wage workers in Detroit (stratified by sex and welfare status) were interviewed in 1969. Data were collected on background characteristics, labor market experiences, and work career histories. The data relate to sexism as an important determinant of income in low-wage groups (women earn less and have lower status jobs),

  18. Welfare Triangles and Economic Policy Analysis.

    ERIC Educational Resources Information Center

    James, Stephen

    1989-01-01

    Shows how the concepts of consumer's surplus and producer's surplus can be related to basic welfare economics. Provides illustrations of the ways in which these concepts can be applied in introductory economics courses. Examines the social cost of monopoly, the tax burden, free trade, tariffs, and the English Channel Tunnel. (KO)

  19. Child Welfare and Stigma: Principles into Practice.

    ERIC Educational Resources Information Center

    Colton, Matthew; And Others

    1997-01-01

    Investigated the stigma attached to child welfare services in the Netherlands, United Kingdom, and Spain. Found that stigma continues to be part of the experience of using and delivering such services, despite positive determination of policies in all three countries that this should not be so. Also found that the experience of stigma can, with…

  20. Immigrants, Welfare Reform, and the Economy

    ERIC Educational Resources Information Center

    Haider, Steven J.; Schoeni, Robert F.; Bao, Yuhua; Danielson, Caroline

    2004-01-01

    The welfare reform bill adopted in the United States in 1996 limited the eligibility of immigrants for several government assistance programs, and early projections estimated that nearly half of the savings associated with the reforms would come from these immigrant restrictions. Several studies have found that subsequent program participation

  1. Immigrants, Welfare Reform, and the Economy

    ERIC Educational Resources Information Center

    Haider, Steven J.; Schoeni, Robert F.; Bao, Yuhua; Danielson, Caroline

    2004-01-01

    The welfare reform bill adopted in the United States in 1996 limited the eligibility of immigrants for several government assistance programs, and early projections estimated that nearly half of the savings associated with the reforms would come from these immigrant restrictions. Several studies have found that subsequent program participation…

  2. Summary: Ecosystem Services and Human Welfare

    EPA Science Inventory

    The ecosystem services paradigm is a framework conceived to engage support among people, especially policy- and decision-makers, for the recognition that human welfare, prosperity, security, and well-being are intrinsically linked to the health of the environment. Simply stated, ...

  3. Global Perspectives on Child Welfare. Preface.

    ERIC Educational Resources Information Center

    Pasztor, Eileen Mayers; McFadden, Emily Jean

    2001-01-01

    Discusses the effects of a global perspective on awareness of issues affecting child welfare worldwide, including warfare, land mines, AIDS, child labor, child sexual exploitation, and immigration. Considers programs and policies from other countries, including nongovernmental organizations, that can be replicated worldwide to better children's

  4. Assuring the welfare of food animals.

    PubMed

    Honey, Laura

    2013-12-14

    There is a plethora of schemes for assuring the welfare of food animals but, with each having different standards and with incomplete coverage of all livestock sectors, consumers are confused about what they all mean. A debate at this year's BVA Congress highlighted the problem, and considered how it might be addressed at a farm and consumer level. Laura Honey reports. PMID:24337085

  5. Multiple-Father Families and Welfare

    ERIC Educational Resources Information Center

    Evenhouse, Eirik; Reilly, Siobhan

    2012-01-01

    In the United States, multipartnered fertility (MPF) has become commonplace. This study provides the first nationally representative measures of women's MPF, across multiple years, using the U.S. Census Bureau's Surveys of Income and Program Participation. Because welfare rules contain strong incentives for MPF, and because MPF is especially

  6. Culture, Cooperation, and the General Welfare

    ERIC Educational Resources Information Center

    Berigan, Nick; Irwin, Kyle

    2011-01-01

    Solutions to social dilemmas require cooperation. Given that there are commonly multiple avenues for cooperation, sometimes social dilemmas require coordination of strategies in addition to sufficient cooperation to be successful. This study examines one social dilemma where such coordination is necessary: supporting the general welfare. Using

  7. Work, Welfare, and Family Well-Being.

    ERIC Educational Resources Information Center

    Sing, Merrile; Hill, Heather; Mendenko, Linda

    As more families move from welfare to work, little is known about the implications of employment for family well-being. This survey and case study examined the effects of employment on the economic, social, and emotional well-being of parents, children, and families. Survey respondents received assistance through Iowa's Family Investment Program…

  8. The welfare state, class, and gender.

    PubMed

    Berlinguer, G

    1992-01-01

    If we compare the welfare state countries with others, from the point of view of both health and health services, the crisis concerns primarily the second group of countries. Nevertheless, difficulties arise also for welfare state policies. The problem is how to respond to neoconservative attacks on social and health rights, and how to change the bureaucratic and medicalized bias of the welfare state. The "golden era" of social insurance and health services, conceived as free access to funds to cope with all the growing needs of the population, is over. Limitations, controls, and priorities have to be established. In Italy and similar countries, the tendency is toward restricting health care for those who have greater needs, cutting funds for prevention, and creating greater inequalities. It is clear that the state must intervene to reduce social inequalities, but at the same time some existing differences (sexual, cultural, ethnic) have an intrinsic value that must be recognized. A policy of free-choice welfare is useful, and has nothing to do with the selective measures that are being introduced. Moreover, a key point has become the relationship between class and gender. The working class continues to be exploited, but new phenomena arise, connected with production and social reproduction and not limited to this sphere. It is true that gender includes social classes, but no social class may represent both sexes, or different ethnic groups, or gender itself. PMID:1735627

  9. Welfare to Work: Solutions or Snake Oil?

    ERIC Educational Resources Information Center

    Ream, John W.; Wagner, Brenda G; Knorr, Robin C.

    2001-01-01

    Focuses on the development and implementation of a customer service call center training program, implemented by Metropolitan Community Colleges (Missouri) to assist welfare recipients overcome the obstacles facing them in the workplace. Discusses components of the program, and its effects on both the consumer and the corporate community. (AUTH/NB)

  10. The Y Chromosome

    ERIC Educational Resources Information Center

    Offner, Susan

    2010-01-01

    The Y chromosome is of great interest to students and can be used to teach about many important biological concepts in addition to sex determination. This paper discusses mutation, recombination, mammalian sex determination, sex determination in general, and the evolution of sex determination in mammals. It includes a student activity that…

  11. Why Chromosome Palindromes?

    PubMed Central

    Betrán, Esther; Demuth, Jeffery P.; Williford, Anna

    2012-01-01

    We look at sex-limited chromosome (Y or W) evolution with particular emphasis on the importance of palindromes. Y chromosome palindromes consist of inverted duplicates that allow for local recombination in an otherwise nonrecombining chromosome. Since palindromes enable intrachromosomal gene conversion that can help eliminate deleterious mutations, they are often highlighted as mechanisms to protect against Y degeneration. However, the adaptive significance of recombination resides in its ability to decouple the evolutionary fates of linked mutations, leading to both a decrease in degeneration rate and an increase in adaptation rate. Our paper emphasizes the latter, that palindromes may exist to accelerate adaptation by increasing the potential targets and fixation rates of incoming beneficial mutations. This hypothesis helps reconcile two enigmatic features of the “palindromes as protectors” view: (1) genes that are not located in palindromes have been retained under purifying selection for tens of millions of years, and (2) under models that only consider deleterious mutations, gene conversion benefits duplicate gene maintenance but not initial fixation. We conclude by looking at ways to test the hypothesis that palindromes enhance the rate of adaptive evolution of Y-linked genes and whether this effect can be extended to palindromes on other chromosomes. PMID:22844637

  12. The Y Chromosome

    ERIC Educational Resources Information Center

    Offner, Susan

    2010-01-01

    The Y chromosome is of great interest to students and can be used to teach about many important biological concepts in addition to sex determination. This paper discusses mutation, recombination, mammalian sex determination, sex determination in general, and the evolution of sex determination in mammals. It includes a student activity that

  13. [New chromosomal syndromes].

    PubMed

    Schluth-Bolard, C; Till, M; Edery, P; Sanlaville, D

    2008-09-01

    Mental retardation occurs in 2-3% of the general population either in isolation or in combination with facial dysmorphism and/or malformations. Chromosomal abnormalities are a most common etiology. Karyotype displays chromosome aberrations in about 10% of patients but it has a limited resolution (5 Mb). Recently, the development of new molecular cytogenetic tools, especially array CGH, allowed to detect smaller abnormalities and increased the diagnosis capability of 15-20%. Among these newly detected rearrangements, some of them are recurrent and define new recognized syndromes. We will first briefly explain the non-allelic homologous recombination (NAHR) mechanism that underlines the origin of recurrent microdeletions and microduplications. Then we will describe eight new syndromes, four microdeletions (del 17q21.31, del 3q29, del 15q24, del 2q32.3q33) and four microduplications (dup 22q11.2, dup 7q11.23, dup 17p11.2, duplication of MECP2). A better knowledge of these new recurrent chromosomal syndromes will allow to improve care for patients, to develop targeted chromosomal diagnosis and to identify genes involved in neurocognitive functions. PMID:18467039

  14. 45 CFR 205.45 - Federal financial participation in relation to State emergency welfare preparedness.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... emergency welfare situations resulting from natural disasters, civil disorders, and enemy caused disasters... with other government and voluntary welfare agencies, and welfare-related business and...

  15. 45 CFR 205.45 - Federal financial participation in relation to State emergency welfare preparedness.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... emergency welfare situations resulting from natural disasters, civil disorders, and enemy caused disasters... with other government and voluntary welfare agencies, and welfare-related business and...

  16. What Use Is Science to Animal Welfare?

    NASA Astrophysics Data System (ADS)

    Webster, A. J. F.

    1998-06-01

    My concern is to question the quality and utility of science in general and ethology in particular as applied to animal welfare. This topic has in the past provoked me to some severe criticism, for example, 'A lot of well-intended welfare research is neither very good science nor very helpful to the animals.... Too much welfare research is (in my opinion) flawed either because it is oversimplistic, or because it is not so much designed to test preconceptions but to reinforce prejudice' (Webster 1994). Dawkins (1997) has recently responded to this challenge, addressing the question 'Why has there not been more progress in welfare research?' Her response is concerned largely with applied ethology. My own criticism was not directed at ethologists in particular. I was more concerned by the misuse of scientific method by those who seek to obtain a so-called 'objective' measurement of something which they preconceive to be a stress (e.g. measurement of plasma concentrations of cortisol or endorphins in animals following transportation). Here the 'objective' measure frequently becomes the test that gives the answer that they want, and if it fails, then they seek other 'objective' markers until they achieve a set of measurements that supports the subjective impression which they had at the outset. My second main concern is that the welfare state of a sentient animal is a very complex affair and cannot be embraced by any single scientific discipline, be it ethology, physiology, molecular or neurobiology. Unfortunately it is also too complex to be embraced by a single-sentence definition. The best I can do is to suggest that it is determined by the capacity of an animal to sustain physical fitness and avoid mental suffering. The assessment of this is necessarily multidisciplinary.

  17. Assessing the welfare of laboratory mice in their home environment using animal-based measures - a benchmarking tool.

    PubMed

    Spangenberg, Elin Mf; Keeling, Linda J

    2016-02-01

    Welfare problems in laboratory mice can be a consequence of an ongoing experiment, or a characteristic of a particular genetic line, but in some cases, such as breeding animals, they are most likely to be a result of the design and management of the home cage. Assessment of the home cage environment is commonly performed using resource-based measures, like access to nesting material. However, animal-based measures (related to the health status and behaviour of the animals) can be used to assess the current welfare of animals regardless of the inputs applied (i.e. the resources or management). The aim of this study was to design a protocol for assessing the welfare of laboratory mice using only animal-based measures. The protocol, to be used as a benchmarking tool, assesses mouse welfare in the home cage and does not contain parameters related to experimental situations. It is based on parameters corresponding to the 12 welfare criteria established by the Welfare Quality project. Selection of animal-based measures was performed by scanning existing published, web-based and informal protocols, and by choosing parameters that matched these criteria, were feasible in practice and, if possible, were already validated indicators of mouse welfare. The parameters should identify possible animal welfare problems and enable assessment directly in an animal room during cage cleaning procedures, without the need for extra equipment. Thermal comfort behaviours and positive emotional states are areas where more research is needed to find valid, reliable and feasible animal-based measures. PMID:25801331

  18. Massachusetts and Scotland: from juvenile justice to child welfare?

    PubMed

    McGhee, Janice; Alice, Lorraine; Waterhouse, Margaret

    2012-01-01

    Comparative data from two systems of dual jurisdiction, the Massachusetts juvenile court and the Scottish children's hearings, is examined to explore the relative use of child welfare and juvenile justice referrals in the lives of children. In Scotland, a radical shift away from juvenile delinquency toward child welfare cases has altered the system's capacity to fulfill a welfare-oriented approach to older adolescents. In Massachusetts, the juvenile court is becoming more welfare-oriented as older adolescents are claimed. PMID:24205555

  19. [Chromosomal organization of the genomes of small-chromosome plants].

    PubMed

    Muravenko, O V; Zelenin, A V

    2009-11-01

    An effective approach to study the chromosome organization in genomes of plants with small chromosomes and/or with low-informative C-banding patterns was developed in the course of investigation of the karyotypes of cotton plant, camomile, flax, and pea. To increase the resolving power of chromosome analysis, methods were worked out for revealing early replication patterns on chromosomes and for artificial impairment of mitotic chromosome condensation with the use of a DNA intercalator, 9-aminoacridine (9-AMA). To estimate polymorphism of the patterns of C-banding of small chromosomes on preparations obtained with the use of 9-AMA, it is necessary to choose a length interval that must not exceed three average sizes of metaphase chromosomes without the intercalator. The use of 9-AMA increases the resolution of differential C- and OR-banding and the precision of physical chromosome mapping by the FISH method. Of particular importance in studying small chromosomes is optimization of the computer-aided methods used to obtain and process chromosome images. The complex approach developed for analysis of the chromosome organization in plant genomes was used to study the karyotypes of 24 species of the genus Linum L. It permitted their chromosomes to be identified for the first time, and, in addition, B chromosomes were discovered and studied in the karyotypes of the species of the section Syllinum. By similarity of the karyotypes, the studied flax species were distributed in eight groups in agreement with the clusterization of these species according to the results of RAPD analysis performed in parallel. Systematic positions and phylogenetic relationships of the studied flax species were verified. Out results can serve as an important argument in favour of the proposal to develop a special program for sequencing the genome of cultivated flax (L. usitatissimum L.), which is a major representative of small-chromosome species. PMID:20058798

  20. A New Fractal Model of Chromosome and DNA Processes

    NASA Astrophysics Data System (ADS)

    Bouallegue, K.

    Dynamic chromosome structure remains unknown. Can fractals and chaos be used as new tools to model, identify and generate a structure of chromosomes?Fractals and chaos offer a rich environment for exploring and modeling the complexity of nature. In a sense, fractal geometry is used to describe, model, and analyze the complex forms found in nature. Fractals have also been widely not only in biology but also in medicine. To this effect, a fractal is considered an object that displays self-similarity under magnification and can be constructed using a simple motif (an image repeated on ever-reduced scales).It is worth noting that the problem of identifying a chromosome has become a challenge to find out which one of the models it belongs to. Nevertheless, the several different models (a hierarchical coiling, a folded fiber, and radial loop) have been proposed for mitotic chromosome but have not reached a dynamic model yet.This paper is an attempt to solve topological problems involved in the model of chromosome and DNA processes. By combining the fractal Julia process and the numerical dynamical system, we have finally found out four main points. First, we have developed not only a model of chromosome but also a model of mitosis and one of meiosis. Equally important, we have identified the centromere position through the numerical model captured below. More importantly, in this paper, we have discovered the processes of the cell divisions of both mitosis and meiosis. All in all, the results show that this work could have a strong impact on the welfare of humanity and can lead to a cure of genetic diseases.

  1. Degeneration of a Nonrecombining Chromosome

    NASA Astrophysics Data System (ADS)

    Rice, William R.

    1994-01-01

    Comparative studies suggest that sex chromosomes begin as ordinary autosomes that happen to carry a major sex determining locus. Over evolutionary time the Y chromosome is selected to stop recombining with the X chromosome, perhaps in response to accumulation of alleles beneficial to the heterogametic but harmful to the homogametic sex. Population genetic theory predicts that a nonrecombining Y chromosome should degenerate. Here this prediction is tested by application of specific selection pressures to Drosophila melanogaster populations. Results demonstrate the decay of a nonrecombining, nascent Y chromosome and the capacity for recombination to ameliorate such decay.

  2. A Profile of Families Cycling on and off Welfare

    ERIC Educational Resources Information Center

    Richberg-Hayes, Lashawn; Freedman, Stephen

    2004-01-01

    This report analyzes the experiences of welfare "cyclers," a group that has received relatively little attention in previous research on welfare dynamics. For this study, "cycling" is defined as receipt of welfare benefits during three or more discrete spells during a four-year observation period. The goals of this report are to understand the

  3. Involving Employers in Welfare-to-Work Efforts.

    ERIC Educational Resources Information Center

    Relave, Nanette

    2001-01-01

    The success of work-centered welfare programs depends on clients connecting to the workforce and sustaining employment. Engaging employers in welfare and workforce development policies and programs is critical to achieving positive labor market outcomes for clients. Employer involvement in welfare-to-work activities can benefit public agencies,

  4. Welfare Reform and the Long-Term Care Workforce

    ERIC Educational Resources Information Center

    Filinson, Rachel; Cone, Donna; Ray, Eileen

    2005-01-01

    The research reported in this paper examined the role of welfare reform in increasing the availability of entry-level workers to meet the rising demand for long-term care employees. Findings from national and statewide evaluations of welfare programs show mixed results in the extent to which beneficiaries could be shifted from welfare caseloads to…

  5. Governmental and Nongovernmental Youth Welfare in the New German Lander.

    ERIC Educational Resources Information Center

    Gawlik, Marion; And Others

    1994-01-01

    Survey of the general conditions of youth welfare departments in eastern Germany revealed severe money shortages. Increasing demands on youth welfare, rising social problems, right-wing extremism, and widespread unemployment among youths cause long-term social problems and prohibit effective youth welfare. (RJM)

  6. Employment among Current and Former Welfare Recipients: A Literature Review

    ERIC Educational Resources Information Center

    Morris, Susan; Santhiveeran, Janaki; Lam, Brian Trung

    2006-01-01

    The primary goal of welfare reform is to move recipients from welfare to work. Several factors influence the employment of welfare recipients. The purpose of this content analysis is to offer a comprehensive understanding of employment characteristics and important personal, family, and employment characteristics that either promote or deter

  7. 12 CFR 24.3 - Public welfare investments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Public welfare investments. 24.3 Section 24.3 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY COMMUNITY AND ECONOMIC DEVELOPMENT ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE INVESTMENTS § 24.3 Public welfare investments. A national bank or...

  8. Pupil Welfare in Finnish Schools -- Communal or Falling Apart?

    ERIC Educational Resources Information Center

    Koskela, Teija; Mtt, Kaarina; Uusiautti, Satu

    2013-01-01

    The need for pupil welfare has increased in schools as has the need to renew the traditional teacher's work. The purpose of this article is to find out how committed the teachers are to pupil welfare work and how the school organisation supports pupil welfare work structurally and practically. The original research was carried out in northern

  9. Patterns of Welfare Attitudes in the Australian Population

    PubMed Central

    Schofield, Timothy P.; Butterworth, Peter

    2015-01-01

    The study of community attitudes toward welfare and welfare recipients is an area of increasing interest. This is not only because negative attitudes can lead to stigmatization and discrimination, but because of the relevance of social attitudes to policy decisions. We quantify the attitudes toward welfare in the Australian population using attitude data from a nationally representative survey (N = 3243). Although there was broad support for the social welfare system, negative attitudes are held toward those who receive welfare benefits. Using canonical correlation analysis we identify multivariate associations between welfare attitudes and respondent demographic characteristics. A primary attitudinal dimension of welfare positivity was found amongst those with higher levels of education, life instability, and personal exposure to the welfare system. Other patterns of negative welfare attitudes appeared to be motivated by beliefs that the respondent’s personal circumstances indicate their deservingness. Moreover, a previously unidentified and unconsidered subset of respondents was identified. This group had positive attitudes toward receiving government benefits despite having no recent experience of welfare. They did, however, possess many of the characteristics that frequently lead to welfare receipt. These results provide insights into not only how attitudinal patterns segment across the population, but are of relevance to policy makers considering how to align welfare reform with community attitudes. PMID:26554361

  10. 43 CFR 17.250 - Health, welfare, and social services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Health, welfare, and social services. 17... 17.250 Health, welfare, and social services. This subpart applies to health, welfare, and other social service programs or activities that receive Federal financial assistance and to recipients...

  11. The American Welfare System and Family Structure: An Historical Perspective

    ERIC Educational Resources Information Center

    Moehling, Carolyn M.

    2007-01-01

    Cross-sectional studies find a positive relationship between a state's welfare benefits and single motherhood. But is this evidence of a "welfare effect" or rather of cross state differences in social attitudes that influence both policy and behavior? This paper demonstrates that the spatial variation in welfare policy long preceded the spatial

  12. Devolution and Welfare Reform: Re-Evaluating "Success"

    ERIC Educational Resources Information Center

    Sheely, Amanda

    2012-01-01

    The passage of welfare reform shifted significant authority for welfare provision from the federal government to state and local governments. Proponents of devolution point to drastic caseload declines as evidence that state-run programs are decreasing dependency among families. However, welfare rolls in many states have remained stagnant or

  13. Microform Retrieval Equipment Guide.

    ERIC Educational Resources Information Center

    National Archives and Records Service (GSA), Washington, DC. Office of Records Management.

    A basis for comparing available equipment against the requirements of the prospective user or purchaser of microform retrieval equipment is provided. As used in the handbook, microform retrieval equipment is defined as any device that is used to locate, enlarge, and display microform images or that produces enlarged hard copy from the images. Only

  14. Mobile Equipment Expands Inventory.

    ERIC Educational Resources Information Center

    McGough, Robert L.; And Others

    1978-01-01

    Describes the Mobile Equipment Modules (MEM) system in Duluth, Minnesota. MEM is a way to hold down costs and increase learning opportunities by consolidating purchases of expensive shop equipment within the school district, grouping the equipment in modules, and scheduling and moving it from school to school as needed. (MF)

  15. The chromosome cycle of prokaryotes

    PubMed Central

    Kuzminov, Andrei

    2013-01-01

    Summary In both eukaryotes and prokaryotes, chromosomal DNA undergoes replication, condensation-decondensation and segregation, sequentially, in some fixed order. Other conditions, like sister-chromatid cohesion (SCC), may span several chromosomal events. One set of these chromosomal transactions within a single cell cycle constitutes the “chromosome cycle”. For many years it was generally assumed that the prokaryotic chromosome cycle follows major phases of the eukaryotic one: -replication-condensation-segregation-(cell division)-decondensation-, with SCC of unspecified length. Eventually it became evident that, in contrast to the strictly consecutive chromosome cycle of eukaryotes, all stages of the prokaryotic chromosome cycle run concurrently. Thus, prokaryotes practice “progressive” chromosome segregation separated from replication by a brief SCC, and all three transactions move along the chromosome at the same fast rate. In other words, in addition to replication forks, there are “segregation forks” in prokaryotic chromosomes. Moreover, the bulk of prokaryotic DNA outside the replication-segregation transition stays compacted. I consider possible origins of this concurrent replication-segregation and outline the “nucleoid administration” system that organizes the dynamic part of the prokaryotic chromosome cycle. PMID:23962352

  16. [Chromosomal Aberrations in Myelodysplastic Syndromes].

    PubMed

    Ru, Xiao; Zhang, Ling-Yan; Li, Ying

    2015-10-01

    Myelodysplastic syndromes (MDS) are a group of clonal hematopioetic disorders characterized by myelodysplasia, decreased peripheral blood cells and high-risk of transformation into acute leukemia. MDS are often accompanied by a variety of chromosomal aberrations which play a role in disease pathogenesis, and are crucial in diagnosis and prognostic evaluation of this disease. About half of the patients with MDS have chromosomal abnormalities, mainly unbalanced chromosomal aberration. Different chromosomal aberration types are associated with different clinical outcome of this disease. Though balanced chromosomal translocations are not common in MDS, it seems that the patients with them have a higher leukemia transformation rate than those with other type of chromosomal aberrations. In this review, the chromosomal aberrations in MDS and their clinical significance for diagnosis and prognosis are briefly summarized. PMID:26524067

  17. High-speed chromosome sorting

    SciTech Connect

    Gray, J.W.; Dean, P.N.; Fuscoe, J.C.; Peters, D.C.; Trask, B.J.; van den Engh, G.J.; van Dilla, M.A.

    1987-10-16

    Dual-beam high-speed sorting has been developed to facilitate purification of chromosomes based on DNA staining with the fluorescent dyes Hoechst 33258 and chromomycin A3. Approximately 200 chromosomes per second of two types can be sorted from a suspension of chromosome isolated from human lymphoblasts while fluorescent objects (chromosomes, debris fragments, chromosome clumps, and nuclei) are processed at the rate of about 20,000 per second. This sorting rate is approximately ten times that possible with conventional sorters. Chromosomes of a single type can be sorted with a purity of about 90 percent. DNA from the sorted chromosomes is suitable for construction of recombinant DNA libraries and for gene mapping.

  18. Chromosome 19 International Workshop

    SciTech Connect

    Pericak-Vance, M.A. . Medical Center); Ropers, H.H. . Dept. of Human Genetics); Carrano, A.J. )

    1993-01-04

    The Second International Workshop on Human Chromosome 19 was hosted on January 25 and 26, 1992, by the Department of Human Genetics, University Hospital Nijmegen, The Netherlands, at the 'Meerdal Conference Center'. The workshop was supported by a grant from the European Community obtained through HUGO, the Dutch Research Organization (NWO) and the Muscular Dystrophy Association (MDA). Travel support for American participants was provided by the Department of Energy. The goals of this workshop were to produce genetic, physical and integrated maps of chromosome 19, to identify inconsistencies and gaps, and to discuss and exchange resources and techniques available for the completion of these maps. The second day of the meeting was largely devoted to region or disease specific efforts. In particular, the meeting served as a platform for assessing and discussing the recent progress made into the molecular elucidation of myotonic dystrophy.

  19. Automated Chromosome Breakage Assessment

    NASA Technical Reports Server (NTRS)

    Castleman, Kenneth

    1985-01-01

    An automated karyotyping machine was built at JPL in 1972. It does computerized karyotyping, but it has some hardware limitations. The image processing hardware that was available at a reasonable price in 1972 was marginal, at best, for this job. In the meantime, NASA has developed an interest in longer term spaceflights and an interest in using chromosome breakage studies as a dosimeter for radiation or perhaps other damage that might occur to the tissues. This uses circulating lymphocytes as a physiological dosimeter looking for chromosome breakage on long-term spaceflights. For that reason, we have reactivated the automated karyotyping work at JPL. An update on that work, and a description of where it appears to be headed is presented.

  20. Welfare Time Limits: An Interim Report Card. The Cross-State Study of Time-Limited Welfare.

    ERIC Educational Resources Information Center

    Bloom, Dan

    A study focused on results from seven of the earliest state welfare reform initiatives with some form of welfare time limit. Four programs--Connecticut, Delaware, Florida, and Wisconsin--- included benefit-termination time limits triggering cancellation of a family's entire welfare grant. Arizona and Indiana imposed benefit-reduction time limits,

  1. Interpreting chromosome aberration spectra.

    PubMed

    Levy, Dan; Reeder, Christopher; Loucas, Bradford; Hlatky, Lynn; Chen, Allen; Cornforth, Michael; Sachs, Rainer

    2007-03-01

    Ionizing radiation can damage cells by breaking both strands of DNA in multiple locations, essentially cutting chromosomes into pieces. The cell has enzymatic mechanisms to repair such breaks; however, these mechanisms are imperfect and, in an exchange process, may produce a large-scale rearrangement of the genome, called a chromosome aberration. Chromosome aberrations are important in killing cells, during carcinogenesis, in characterizing repair/misrepair pathways, in retrospective radiation biodosimetry, and in a number of other ways. DNA staining techniques such as mFISH (multicolor fluorescent in situ hybridization) provide a means for analyzing aberration spectra by examining observed final patterns. Unfortunately, an mFISH observed final pattern often does not uniquely determine the underlying exchange process. Further, resolution limitations in the painting protocol sometimes lead to apparently incomplete final patterns. We here describe an algorithm for systematically finding exchange processes consistent with any observed final pattern. This algorithm uses aberration multigraphs, a mathematical formalism that links the various aspects of aberration formation. By applying a measure to the space of consistent multigraphs, we will show how to generate model-specific distributions of aberration processes from mFISH experimental data. The approach is implemented by software freely available over the internet. As a sample application, we apply these algorithms to an aberration data set, obtaining a distribution of exchange cycle sizes, which serves to measure aberration complexity. Estimating complexity, in turn, helps indicate how damaging the aberrations are and may facilitate identification of radiation type in retrospective biodosimetry. PMID:17456013

  2. Interpreting Chromosome Aberration Spectra

    NASA Technical Reports Server (NTRS)

    Levy, Dan; Reeder, Christopher; Loucas, Bradford; Hlatky, Lynn; Chen, Allen; Cornforth, Michael; Sachs, Rainer

    2007-01-01

    Ionizing radiation can damage cells by breaking both strands of DNA in multiple locations, essentially cutting chromosomes into pieces. The cell has enzymatic mechanisms to repair such breaks; however, these mechanisms are imperfect and, in an exchange process, may produce a large-scale rearrangement of the genome, called a chromosome aberration. Chromosome aberrations are important in killing cells, during carcinogenesis, in characterizing repair/misrepair pathways, in retrospective radiation biodosimetry, and in a number of other ways. DNA staining techniques such as mFISH ( multicolor fluorescent in situ hybridization) provide a means for analyzing aberration spectra by examining observed final patterns. Unfortunately, an mFISH observed final pattern often does not uniquely determine the underlying exchange process. Further, resolution limitations in the painting protocol sometimes lead to apparently incomplete final patterns. We here describe an algorithm for systematically finding exchange processes consistent with any observed final pattern. This algorithm uses aberration multigraphs, a mathematical formalism that links the various aspects of aberration formation. By applying a measure to the space of consistent multigraphs, we will show how to generate model-specific distributions of aberration processes from mFISH experimental data. The approach is implemented by software freely available over the internet. As a sample application, we apply these algorithms to an aberration data set, obtaining a distribution of exchange cycle sizes, which serves to measure aberration complexity. Estimating complexity, in turn, helps indicate how damaging the aberrations are and may facilitate identification of radiation type in retrospective biodosimetry.

  3. Chromosome abnormalities in glioma

    SciTech Connect

    Li, Y.S.; Ramsay, D.A.; Fan, Y.S.

    1994-09-01

    Cytogenetic studies were performed in 25 patients with gliomas. An interesting finding was a seemingly identical abnormality, an extra band on the tip of the short arm of chromosome 1, add(1)(p36), in two cases. The abnormality was present in all cells from a patient with a glioblastoma and in 27% of the tumor cells from a patient with a recurrent irradiated anaplastic astrocytoma; in the latter case, 7 unrelated abnormal clones were identified except 4 of those clones shared a common change, -Y. Three similar cases have been described previously. In a patient with pleomorphic astrocytoma, the band 1q42 in both homologues of chromosome 1 was involved in two different rearrangements. A review of the literature revealed that deletion of the long arm of chromosome 1 including 1q42 often occurs in glioma. This may indicate a possible tumor suppressor gene in this region. Cytogenetic follow-up studies were carried out in two patients and emergence of unrelated clones were noted in both. A total of 124 clonal breakpoints were identified in the 25 patients. The breakpoints which occurred three times or more were: 1p36, 1p22, 1q21, 1q25, 3q21, 7q32, 8q22, 9q22, 16q22, and 22q13.

  4. Captive care and welfare considerations for beavers.

    PubMed

    Campbell-Palmer, Risn; Rosell, Frank

    2015-01-01

    Beavers (Castor spp.) tend not to be a commonly held species and little published material exists relating to their captive care. We review published material and discuss husbandry issues taking into account the requirements of wild beavers. As social mammals with complex chemical communication systems and with such an ability to modify their environments, studies of wild counterparts suggest the captive requirements of beavers may actually be more sophisticated than generally perceived. Common field techniques may have practical application in the captive setting. Their widespread utilisation in conservation, including reintroductions, translocations and habitat management, also requires components of captive care. As welfare science advances there is increasing pressure on captive collections to improve standards and justify the keeping of animals. Conservation science is increasingly challenged to address individual welfare standards. Further research focusing on the captive care of beavers is required. PMID:25653085

  5. Generalized Nutrient Taxes Can Increase Consumer Welfare.

    PubMed

    Bishai, David

    2015-11-01

    Certain nutrients can stimulate appetite making them fattening in a way that is not fully conveyed by the calorie content on the label. For rational eaters, this information gap could be corrected by more labeling. As an alternative, this paper proposes a set of positive and negative taxes on the fattening and slimming nutrients in food rather than on the food itself. There are conditions under which this tax plus subsidy system could increase welfare by stopping unwanted weight gain while leaving the final retail price of food unchanged. A nutrient tax system could improve welfare if fattening nutrients, net of their effect on weight, are inferior goods and the fiscal cost of administering the tax is sufficiently low. More data on the price elasticity of demand for nutrients as well as data on how specific nutrients affect satiety and how total calorie intake would be necessary before one could be sure a nutrient tax would work in practice. PMID:25241653

  6. When do fat taxes increase consumer welfare?

    PubMed

    Lusk, Jayson L; Schroeter, Christiane

    2012-11-01

    Previous analyses of fat taxes have generally worked within an empirical framework in which it is difficult to determine whether consumers benefit from the policy. This note outlines on simple means to determine whether consumers benefit from a fat tax by comparing the ratio of expenditures on the taxed good to the weight effect of the tax against the individual's willingness to pay for a one-pound weight reduction. Our empirical calculations suggest that an individual would have to be willing to pay about $1500 to reduce weight by one pound for a tax on sugary beverages to be welfare enhancing. The results suggest either that a soda tax is very unlikely to increase individual consumer welfare or that the policy must be justified on some other grounds that abandon standard rationality assumptions. PMID:21887810

  7. Welfare during stunning and slaughter of poultry.

    PubMed

    Raj, M

    1998-12-01

    This paper describes research on the electrical stunning of poultry and the problems of achieving an effective humane stun with water bath stunners. The welfare and meat quality advantages of using gas mixtures to stun and kill birds are then described. The evidence strongly suggests that chickens and turkeys can be killed very humanely using either 90% argon in air or a mixture of 30% carbon dioxide and 60% argon in air. PMID:9872584

  8. Global perspectives on animal welfare: Africa.

    PubMed

    Masiga, W N; Munyua, S J M

    2005-08-01

    Livestock production systems, production objectives, the cultural values of livestock keepers, and the close relationship between keepers and their livestock have evolved over the years and have influenced the quality of animal welfare in Africa. An equivalent level and quality of care is not evident for companion animals, especially dogs and donkeys, who are often mistreated and physically abused. In the densely populated highland and humid coastal belts of Africa, profit-driven commercial large-scale intensive livestock production systems predominate. As the main production objective of these operations is to maximise profit, the operators of these production systems do not exhibit the same kind of attachment to their livestock as traditional farmers. In some large-scale commercial systems animals and birds are kept in sub-standard poorly constructed structures that greatly restrict the animals' movements. In Africa, conservation of wildlife habitats is part of animal welfare, but due to an increasing human population and a greater demand for land for grazing, cultivation, and housing, wildlife reserves are quickly diminishing. This essentially means that the land that was previously set aside for wildlife and forests is being encroached upon and previously unsettled plains and marginal lands are being used for agriculture and mining. In most places there is significant conflict between humans and wildlife, such that wildlife are considered to be pests that need to be destroyed. This is a particular problem in areas where wildlife have destroyed crops, attacked man and/or livestock, or there has been disease transmission between animals and humans. In situations and/or areas that do not have official animal control services, crude weapons, poisons, and traps are used to kill the wildlife. Animal welfare issues, domestic and wildlife related, need to be urgently addressed through policy and legal frameworks and supported by community awareness of, education about, and participation in, animal welfare issues. PMID:16358509

  9. Renewal of radiological equipment.

    PubMed

    2014-10-01

    In this century, medical imaging is at the heart of medical practice. Besides providing fast and accurate diagnosis, advances in radiology equipment offer new and previously non-existing options for treatment guidance with quite low morbidity, resulting in the improvement of health outcomes and quality of life for the patients. Although rapid technological development created new medical imaging modalities and methods, the same progress speed resulted in accelerated technical and functional obsolescence of the same medical imaging equipment, consequently creating a need for renewal. Older equipment has a high risk of failures and breakdowns, which might cause delays in diagnosis and treatment of the patient, and safety problems both for the patient and the medical staff. The European Society of Radiology is promoting the use of up-to-date equipment, especially in the context of the EuroSafe Imaging Campaign, as the use of up-to-date equipment will improve quality and safety in medical imaging. Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or renewal. This plan should look forward a minimum of 5 years, with annual updates. Teaching points Radiological equipment has a definite life cycle span, resulting in unavoidable breakdown and decrease or loss of image quality which renders equipment useless after a certain time period. Equipment older than 10 years is no longer state-of-the art equipment and replacement is essential. Operating costs of older equipment will be high when compared with new equipment, and sometimes maintenance will be impossible if no spare parts are available. Older equipment has a high risk of failure and breakdown, causing delays in diagnosis and treatment of the patient and safety problems both for the patient and the medical staff. Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or replacement. This plan should look forward a minimum of 5 years, with annual updating. PMID:25230589

  10. Rapid animal welfare assessment: an archaeological approach

    PubMed Central

    Schork, Ivana Gabriela; Young, Robert John

    2014-01-01

    The welfare of an individual depends on its capacity to overcome suboptimal conditions in its environment; otherwise, its physical and psychological health becomes compromised. A situation that clearly indicates lack of control of the environment is the expression of abnormal behaviours, such as stereotypies. This study aimed to verify the well-being of police horses using a new rapid form of welfare assessment: an archaeological approach. To this end, we sampled and quantified marks found on the stables, deposited as a result of abnormal behaviour. We cross-referenced these physical marks with veterinary records of diseases, such as colic, known to be associated with stress. A total of 46 horses were sampled and the results showed a significant medium-strength, positive correlation between bite mark frequency on stable doors and the incidence of colic. A weak significant positive correlation was found between length of scratch marks (from pawing) and the incidence of lameness. We conclude that these marks reflect the accumulated expression of abnormal behaviour and can provide rapid insight into the welfare of individual animals. PMID:25209197

  11. Slowed ageing, welfare, and population problems.

    PubMed

    Wareham, Christopher

    2015-10-01

    Biological studies have demonstrated that it is possible to slow the ageing process and extend lifespan in a wide variety of organisms, perhaps including humans. Making use of the findings of these studies, this article examines two problems concerning the effect of life extension on population size and welfare. The first--the problem of overpopulation--is that as a result of life extension too many people will co-exist at the same time, resulting in decreases in average welfare. The second--the problem of underpopulation--is that life extension will result in too few people existing across time, resulting in decreases in total welfare. I argue that overpopulation is highly unlikely to result from technologies that slow ageing. Moreover, I claim that the problem of underpopulation relies on claims about life extension that are false in the case of life extension by slowed ageing. The upshot of these arguments is that the population problems discussed provide scant reason to oppose life extension by slowed ageing. PMID:26246312

  12. Citizen empowerment using healthcare and welfare cards.

    PubMed

    Cheshire, Paul

    2006-01-01

    Cards are used in health and welfare to establish the identity of the person presenting the card; to prove their entitlement to a welfare or healthcare service; to store data needed within the care process; and to store data to use in the administration process. There is a desire to empower citizens - to give them greater control over their lives, their health and wellbeing. How can a healthcare and welfare card support this aim? Does having a card empower the citizen? What can a citizen do more easily, reliably, securely or cost-effectively because they have a card? A number of possibilities include: Choice of service provider; Mobility across regional and national boundaries; Privacy; and Anonymity. But in all of these possibilities a card is just one component of a total system and process, and there may be other solutions--technological and manual. There are risks and problems from relying on a card; and issues of Inclusion for people who are unable use a card. The article concludes that: cards need to be viewed in the context of the whole solution; cards are not the only technological mechanism; cards are not the best mechanism in all circumstances; but cards are very convenient method in very many situations. PMID:17095830

  13. Rapid animal welfare assessment: an archaeological approach.

    PubMed

    Schork, Ivana Gabriela; Young, Robert John

    2014-09-01

    The welfare of an individual depends on its capacity to overcome suboptimal conditions in its environment; otherwise, its physical and psychological health becomes compromised. A situation that clearly indicates lack of control of the environment is the expression of abnormal behaviours, such as stereotypies. This study aimed to verify the well-being of police horses using a new rapid form of welfare assessment: an archaeological approach. To this end, we sampled and quantified marks found on the stables, deposited as a result of abnormal behaviour. We cross-referenced these physical marks with veterinary records of diseases, such as colic, known to be associated with stress. A total of 46 horses were sampled and the results showed a significant medium-strength, positive correlation between bite mark frequency on stable doors and the incidence of colic. A weak significant positive correlation was found between length of scratch marks (from pawing) and the incidence of lameness. We conclude that these marks reflect the accumulated expression of abnormal behaviour and can provide rapid insight into the welfare of individual animals. PMID:25209197

  14. Animal health and welfare: equivalent or complementary?

    PubMed

    Nicks, B; Vandenheede, M

    2014-04-01

    The concepts of 'health' and 'welfare', whether applied to humans or animals, are increasingly becoming linked. But are they really indissociable, or even synonymous? Although human health is generally defined as a complete state of physical, mental and social well-being, animal health is still considered as simply the absence of disease. However, recent advances in scientific knowledge are forcing us to revise our ideas about the mental complexity of animals and to recognise their ability to feel emotions and to have needs and a degree of consciousness. The precise objective of animal welfare science is to study their mental states and their ability to adapt to domestication. Pending a global application of this concept of health, including mental health, to animals as well as to humans, the idea of welfare remains an important element in addition to traditional health concerns. More generally, this linkage fuels the ethical debate about the ways in which people use animals, prompting society to change its stance on some aspects of the issue. PMID:25000781

  15. 45 CFR 605.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Health, welfare, and other social services. 605.52 Section 605.52 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... ASSISTANCE Health, Welfare, and Social Services § 605.52 Health, welfare, and other social services....

  16. 45 CFR 605.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Health, welfare, and other social services. 605.52 Section 605.52 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... ASSISTANCE Health, Welfare, and Social Services § 605.52 Health, welfare, and other social services....

  17. 45 CFR 605.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Health, welfare, and other social services. 605.52 Section 605.52 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... ASSISTANCE Health, Welfare, and Social Services 605.52 Health, welfare, and other social services....

  18. RETRIEVAL EQUIPMENT DESCRIPTIONS

    SciTech Connect

    J. Steinhoff

    1997-08-25

    The objective and the scope of this document are to list and briefly describe the major mobile equipment necessary for waste package (WP) retrieval from the proposed subsurface nuclear waste repository at Yucca Mountain. Primary performance characteristics and some specialized design features of the equipment are explained and summarized in the individual subsections of this document. There are no quality assurance requirements or QA controls in this document. Retrieval under normal conditions is accomplished with the same fleet of equipment as is used for emplacement. Descriptions of equipment used for retrieval under normal conditions is found in Emplacement Equipment Descriptions, DI: BCAF00000-01717-5705-00002 (a document in progress). Equipment used for retrieval under abnormal conditions is addressed in this document and consists of the following: (1) Inclined Plane Hauler; (2) Bottom Lift Transporter; (3) Load Haul Dump (LHD) Loader; (4) Heavy Duty Forklift for Emplacement Drifts; (5) Covered Shuttle Car; (6) Multipurpose Vehicle; and (7) Scaler.

  19. The preferred role and perceived performance of the welfare state: European welfare attitudes from a multidimensional perspective.

    PubMed

    Roosma, Femke; van Oorschot, Wim; Gelissen, John

    2014-03-01

    Welfare state support has two core dimensions: attitudes about what the welfare state should do and beliefs about its actual performance. People can combine any position on one dimension with any position on the other, yielding four opinion clusters: people can combine preferences for a relatively strong role of the welfare state with a perception of a relatively low or high welfare state performance; likewise, people preferring a small role of the welfare state can perceive a high or low performing welfare state. We apply Latent Class Factor Analysis to data of 22 European countries from the 2008/9 European Social Survey. We find that each of the four clusters contains a substantial proportion of respondents that differs between welfare regimes. In addition, cluster membership is also related to covariates that measure people's structural positions and ideological preferences. PMID:24468444

  20. Shoulder rehabilitation: equipment - - modifications.

    PubMed

    Einhorn, A R

    1985-01-01

    A systematic approach toward weight-training equipment is needed in the physical therapy clinic and in establishing guidelines for the home program. Many different types of exercise equipment are currently being used. With an aggressive patient population, the physical therapist should become familiar with the various types of equipment now available in many of the exercise centers. J Orthop Sports Phys Ther 1985;6(4):247-253. PMID:18802307

  1. From cruelty to welfare: the emergence of farm animal welfare in Britain, 1964-71.

    PubMed

    Woods, Abigail

    2012-03-01

    There is a long history of concern in Britain for how animals are treated. Until the 1960s, these concerns were expressed largely in terms of cruelty or suffering, which was prevented through various acts of Parliament. Over the period 1964-71, amidst public debates about intensive farming, a new discourse of animal welfare emerged. To understand what welfare meant and how it became established as a term, a concept and a target of government regulation, it is necessary to examine farming politics and practices, the existing tradition of animal protection and attempts to rethink the nature of animal suffering. PMID:22192762

  2. Spatial organization of bacterial chromosomes

    PubMed Central

    Wang, Xindan; Rudner, David Z.

    2014-01-01

    Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a deeper characterization of chromosome dynamics in the original model systems have provided a broader and more complete picture of both chromosome organization and the activities that generate the observed spatial patterns. Here, we summarize these different patterns highlighting similarities and differences and discuss the protein factors that help establish and maintain them. PMID:25460798

  3. A Survey of Chinese Citizens’ Perceptions on Farm Animal Welfare

    PubMed Central

    You, Xiaolin; Li, Yibo; Zhang, Min; Yan, Huoqi; Zhao, Ruqian

    2014-01-01

    Farm animal welfare has been gradually recognized as an important issue in most parts of the world. In China, domestic animals were traditionally raised in backyard and treated as an important component of family wealth. Industrialization of animal production brings forth the farm animal welfare concerns recently in China, yet the modern concept of animal welfare has not been publicized and a comprehensive recognition on how consumers and farmers perceive animal welfare is lacking. Therefore, we conducted a survey on public opinions toward farm animal welfare in China, based on pigs (including sows, piglets, and fattening pigs), domestic fowls (including layers and broilers) and their products. From 6,006 effective questionnaires approximately two thirds of the respondents had never heard of ‘animal welfare’; 72.9% of the respondents claimed that, for the sake of animal derived food safety, human beings should improve the rearing conditions for pigs and domestic fowls; 65.8% of the respondents totally or partly agreed on establishing laws to improve animal welfare; more than half of the respondents were willing, or to some extent willing, to pay more for high-welfare animal products, whereas 45.5% of the respondents were not willing or reluctant to pay more. In summary, farm animal welfare is still in its early stage of development and more efforts are needed to improve the public conception to animal welfare in the process of establishing farm animal welfare standards and legislations in China. PMID:25314159

  4. Chromosome Connections: Compelling Clues to Common Ancestry

    ERIC Educational Resources Information Center

    Flammer, Larry

    2013-01-01

    Students compare banding patterns on hominid chromosomes and see striking evidence of their common ancestry. To test this, human chromosome no. 2 is matched with two shorter chimpanzee chromosomes, leading to the hypothesis that human chromosome 2 resulted from the fusion of the two shorter chromosomes. Students test that hypothesis by looking for…

  5. Chromosome Connections: Compelling Clues to Common Ancestry

    ERIC Educational Resources Information Center

    Flammer, Larry

    2013-01-01

    Students compare banding patterns on hominid chromosomes and see striking evidence of their common ancestry. To test this, human chromosome no. 2 is matched with two shorter chimpanzee chromosomes, leading to the hypothesis that human chromosome 2 resulted from the fusion of the two shorter chromosomes. Students test that hypothesis by looking for

  6. Influences of Maternal Care on Chicken Welfare

    PubMed Central

    Edgar, Joanne; Held, Suzanne; Jones, Charlotte; Troisi, Camille

    2016-01-01

    Simple Summary For a domestic chick, the mother hen is an important role model; chicks learn a great deal from their mother about what to peck, when to rest and how to behave when there is a threat. However, in large farms, natural brooding is not commercially viable and so chicks are hatched in large incubators and reared artificially. Chicks reared without a mother in this way are more fearful and more likely to develop behavioural problems, such as feather pecking. We discuss the important features of maternal care in chickens, the behavioural consequences of deprivation, and the welfare implications on commercial farms. We finish by suggesting ways to simulate natural maternal care to improve commercial chick rearing practice. Abstract In domestic chickens, the provision of maternal care strongly influences the behavioural development of chicks. Mother hens play an important role in directing their chicks’ behaviour and are able to buffer their chicks’ response to stressors. Chicks imprint upon their mother, who is key in directing the chicks’ behaviour and in allowing them to develop food preferences. Chicks reared by a mother hen are less fearful and show higher levels of behavioural synchronisation than chicks reared artificially. In a commercial setting, more fearful chicks with unsynchronised behaviour are more likely to develop behavioural problems, such as feather pecking. As well as being an inherent welfare problem, fear can also lead to panic responses, smothering, and fractured bones. Despite the beneficial effects of brooding, it is not commercially viable to allow natural brooding on farms and so chicks are hatched in large incubators and reared artificially, without a mother hen. In this review we cover the literature demonstrating the important features of maternal care in domestic chickens, the behavioural consequences of deprivation and the welfare implications on commercial farms. We finish by suggesting ways to use research in natural maternal care to improve commercial chick rearing practice. PMID:26742081

  7. The welfare of livestock transported by ship.

    PubMed

    Phillips, Clive J C; Santurtun, Eduardo

    2013-06-01

    The transport of livestock by ship is growing in importance, but there are concerns about the welfare impact on the animals. Short sea journeys are usually completed in the vehicles that are used to transport the animals by road, and injury and stress can result. Long sea journeys require offloading of the animals into pens, where they are mixed and provided with feed, water and sometimes artificial ventilation. In addition, animals are often exposed to high stocking densities, elevated temperature and ammonia concentration, as well as noise and changes in photoperiod and light intensity. Mortality rate is the main measure of welfare used by the Australian live export industry for long distance shipments, and the rate is higher at sea compared to the same period of transport on land. Heat stress often challenges livestock when they are transported from cold to hot regions at high stocking densities with no diurnal temperature fluctuation. Sheep cope with heat stress better than cattle, but can still develop respiratory alkalosis if hyperventilation ensues. Bos taurus cattle cope less well with heat stress than Bos indicus breeds. High ammonia concentrations may accumulate on long voyages, causing mucosal irritation and pulmonary inflammation. Some sheep and goats do not adapt to the pellets provided after extensive grazing in Australia, resulting in inanition, often in combination with salmonellosis, which together are the main cause of high mortality rates. Long distance transport may also result in disease transmission to the recipient country and high standards of biosecurity are necessary. It is concluded that there are significant risks to the welfare of livestock caused by transporting them in ships, especially over long distances. PMID:23473873

  8. Chromosomal abnormalities in oocytes.

    PubMed

    Plachot, M

    2001-10-22

    Since the beginning of in vitro fertilization (IVF), basic research has provided insight in the field of human reproduction, especially in genetics. Indeed, the contribution of chromosomal abnormalities to oocyte disorders and impaired embryonic development is now well known. Of oocytes that fail to fertilize after in vitro insemination, 26.5% have been found to be abnormal, with 13.3% showing hypohaploidy, 8.1% hyperhaploidy, 1.6% structural abnormalities and 3.5% diploidy. The total incidence of abnormalities seems to be correlated with the fertility status of the woman. It is higher in oocytes from women with tubal or unexplained infertility than in those from women whose husband's infertility is the sole cause of infertility in the couple. Although few oocytes recovered during natural cycles have been studied, gonadotropins, which are widely used to stimulate follicle growth and ovulation, do not increase the risk of abnormalities. The effect of maternal age on fetal aneuploidy, well documented at birth, has not been unambiguously shown to result from an increase in the frequency of aneuploid oocytes. Intra- and extra-follicular influences (perifollicular microvasculature, oxygenation, and the presence of residues from cigarette smoke) may disturb maturation, leading to immaturity and aneuploidy. Thus, oocyte meiosis is very sensitive to endogenous and exogenous factors that could result in oocytes with chromosomal abnormalities and therefore, abnormal zygotes. PMID:11576735

  9. A fractal model of chromosomes and chromosomal DNA replication.

    PubMed

    Takahashi, M

    1989-11-01

    With the aim of clarifying topological problems involved in the process of chromosomal DNA replication, a fractal model of chromosomes was built based on the assumption that a part of a chromosome, e.g. a radial loop, is similar in shape to a whole chromosome and each radial loop represents structures in the lower-order organization (an assumption of self-similarity). Several other assumptions used include (i) one continuous DNA fiber makes a whole chromosome (a unineme hypothesis), (ii) in situ DNA exists in the form of a double duplex or a tetraplex which is made of two duplex DNAs, although a duplex DNA may appear transiently in S-phase (multi-strandedness hypothesis) and (iii) torsional stress on a DNA fiber causes the fiber to supercoil and thus stabilizes chromosome structure (torque-based stabilization). This model allowed to calculate of a fractal dimension of a representative metaphase chromosome (e.g. d = 2.34), to predict the mode of replication of double duplex and to furnish a topological basis for the decondensation unit hypothesis. It must also be admitted that all the arguments in this report except for the possible existence of split telomeres hold true without assuming a tetraplex organization of chromosomes. Implications of this model was discussed and the importance of the fractal dimension as a measure of chromatin condensation stressed. PMID:2699341

  10. Revolutionizing Child Welfare with Outcomes Management

    PubMed Central

    Toche-Manley, Linda L.; Dietzen, Laura; Nankin, Jesse; Beigel, Astrid

    2013-01-01

    Outcomes management technology holds great promise for improving the quality of services provided to youth in the child welfare system. Advantages include better detection of behavioral health and trauma-related issues, early indicators of case progress or risk of failure and program- and system-level learning. Yet organizational barriers to implementation persist. Attention is spent in this paper on addressing these barriers so the use of outcomes management technology becomes a common practice. A model for predicting resiliency is presented, along with case examples demonstrating its potential use for treatment planning and monitoring progress. PMID:23460130

  11. Bangladeshis in London: a challenge to welfare.

    PubMed

    Curtis, S E; Ogden, P E

    1986-12-01

    "Immigrants of Bangladeshi origin living in Britain are a relatively small part of the population from the New Commonwealth. They are, however, highly distinctive, particularly in their degree of residential concentration within parts of inner London. The paper has two aims: first, using 1981 census data, to plot immigrant distribution within a national and London-wide context; second, to explore some of the implications of this concentration for the provision of welfare services, particularly health, within one of the city's most deprived boroughs." (SUMMARY IN FRE AND SPA) PMID:12314651

  12. The Welfare Effects of Medical Malpractice Liability

    PubMed Central

    Lakdawalla, Darius N.; Seabury, Seth A.

    2013-01-01

    We use variation in the generosity of local juries to identify the causal impact of medical malpractice liability on social welfare. Growth in malpractice payments contributed at most 5 percentage points to the 33% total real growth in medical expenditures from 1990-2003. On the other hand, malpractice leads to modest mortality reductions; the value of these more than likely exceeds the costs of malpractice liability. Therefore, reducing malpractice liability is unlikely to have a major impact on health care spending, and unlikely to be cost-effective over conventionally accepted values of a statistical life. PMID:23526860

  13. Shipboard Electronic Equipments.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    Fundamentals of major electronic equipments on board ships are presented in this text prepared for naval officers in general. Basic radio principles are discussed in connection with various types of transmitters, receivers, antennas, couplers, transfer panels, remote-control units, frequency standard equipments, teletypewriters, and facsimile…

  14. Equipment & New Products.

    ERIC Educational Resources Information Center

    Poitras, Adrian W., Ed.

    1977-01-01

    Presents several new products and equipment for teaching college science courses such as laser optics bench, portable digital thermometer, solar energy furnaces and blackboard optics kit. A description of all equipment or products, cost, and addresses of manufacturers are also included. (HM)

  15. School optical equipment

    NASA Astrophysics Data System (ADS)

    Bilmes, G. M.; Bolognini, Nestor A.; Gallardo, Mario; Tocho, Jorge O.; Trivi, Marcelo; Aljanati, D.; Dicovskiy, E.; Propato, J. L.

    2001-08-01

    A school optical equipment has been designed and developed. It is the result from the cooperative activities of researchers and experts in didactic of the science. The equipment includes a handbook, experimental guides and proposals to be carried in the classroom.

  16. Engineer Equipment Mechanic.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    Developed as part of the Marine Corps Institute (MCI) correspondence training program, this course on engineer equipment mechanics is designed to advance the professional competence of privates through sergeants as equipment mechanics, Military Occupation Specialty 1341, and is adaptable for nonmilitary instruction. Introductory materials include…

  17. Adaptive Recreational Equipment.

    ERIC Educational Resources Information Center

    Schilling, Mary Lou, Ed.

    1983-01-01

    Designed for teachers interested in therapeutic recreation, the document lists sources of adaptive recreational equipment and their homemade counterparts. Brief descriptions for ordering or constructing recreational equipment for the visually impaired, poorly coordinated, physically impaired, and mentally retarded are given. Specific adaptations

  18. Troubleshooting rotating equipment

    SciTech Connect

    Wong, R.F. )

    1992-10-01

    This paper reports that equipment problems in a Peruvian refinery illustrate the process engineer's role as a troubleshooter. Examples show that rotating equipment problems can stem from mechanical or process factors and involve both inspection/maintenance specialists and process engineers.

  19. Technology Equipment Rooms.

    ERIC Educational Resources Information Center

    Day, C. William

    2001-01-01

    Examines telecommunications equipment room design features that allow for growth and can accommodate numerous equipment replacements and upgrades with minimal service disruption and with minimal cost. Considerations involving the central hub, power and lighting needs, air conditioning, and fire protection are discussed. (GR)

  20. Selecting WP Equipment.

    ERIC Educational Resources Information Center

    Casady, Mona J.

    1981-01-01

    Suggestions for schools considering the purchase of word processing equipment are presented. Procedures for selecting equipment include getting information on prices, servicing, warranties, training, speed of printing, and quality of output. Choices to make include brand vs. service, price vs. service, and variety vs. limitations of brands. (CT)

  1. Equipment Operator 1 & C.

    ERIC Educational Resources Information Center

    Naval Education and Training Program Development Center, Pensacola, FL.

    The Rate Training Manual and Nonresident Career Course (RTM/NRCC) form a self-study package to assist Navy Equipment Operators First and Chief in fulfilling the requirements of their rating. (Navy Equipment Operators First and Chief direct and coordinate efforts of individuals and crews in construction, earthmoving, roadbuilding, quarrying, and

  2. Attitudes of meat retailers to animal welfare in Spain.

    PubMed

    Miranda-de la Lama, Genaro C; Seplveda, Wilmer S; Villarroel, Morris; Mara, Gustavo A

    2013-11-01

    This study analyzes retailer attitude towards animal welfare in Spain, and how this attitude has changed over recent years (2006-2011). Retailers were concerned about animal welfare issues but a declining trend is observed recently, probably due to the financial crisis. The concern about animal welfare was affected by sex, with women retailers expressing a more positive attitude towards animal welfare issues than men. Retailers, based on their experience, perceive a low level of willingness to pay more for welfare friendly products (WFP) on behalf of their customers. This fact is reflected in the sales of the WFP, which declined from 2006 to 2011. The main reason for consumers to buy WFP, according to retailer perception, is organoleptic quality, with improved welfare being second. The results obtained provide a pessimistic picture in relation to the current market positioning of WFP, which is probably a consequence of market contraction. PMID:23797014

  3. Animal Welfare in Different Human Cultures, Traditions and Religious Faiths

    PubMed Central

    Szűcs, E.; Geers, R.; Jezierski, T.; Sossidou, E. N.; Broom, D. M.

    2012-01-01

    Animal welfare has become a growing concern affecting acceptability of agricultural systems in many countries around the world. An earlier Judeo-Christian interpretation of the Bible (1982) that dominion over animals meant that any degree of exploitation was acceptable has changed for most people to mean that each person has responsibility for animal welfare. This view was evident in some ancient Greek writings and has parallels in Islamic teaching. A minority view of Christians, which is a widespread view of Jains, Buddhists and many Hindus, is that animals should not be used by humans as food or for other purposes. The commonest philosophical positions now, concerning how animals should be treated, are a blend of deontological and utilitarian approaches. Most people think that extremes of poor welfare in animals are unacceptable and that those who keep animals should strive for good welfare. Hence animal welfare science, which allows the evaluation of welfare, has developed rapidly. PMID:25049508

  4. Increasing Research Capacity in Ontario Child Welfare Organizations: A Unique University-Child Welfare Agency Partnership

    ERIC Educational Resources Information Center

    Fallon, Barbara; Trocm, Nico; Van Wert, Melissa; Budau, Krista; Ballantyne, Mary; Lwin, Kristen

    2015-01-01

    The objective of this article is to describe the successes and challenges of a unique knowledge mobilization initiative that was funded through the Social Sciences and Humanities Research Council of Canada. This initiative focused on promoting knowledge mobilization by increasing the capacity of child welfare organizations in Ontario to conduct

  5. On Welfare and Terror: Social Welfare Policies and Political-Economic Roots of Terrorism

    ERIC Educational Resources Information Center

    Burgoon, Brian

    2006-01-01

    This article argues that social welfare policies may reduce international and domestic terrorism. Social policies likely affect terrorism in offsetting ways but, on balance, should diminish preferences for terrorism by reducing economic insecurity, inequality, poverty, and religious-political extremism. Thus, countries with more generous welfare…

  6. Increasing Research Capacity in Ontario Child Welfare Organizations: A Unique University-Child Welfare Agency Partnership

    ERIC Educational Resources Information Center

    Fallon, Barbara; Trocmé, Nico; Van Wert, Melissa; Budau, Krista; Ballantyne, Mary; Lwin, Kristen

    2015-01-01

    The objective of this article is to describe the successes and challenges of a unique knowledge mobilization initiative that was funded through the Social Sciences and Humanities Research Council of Canada. This initiative focused on promoting knowledge mobilization by increasing the capacity of child welfare organizations in Ontario to conduct…

  7. Kinship Care as a Child Welfare Service: The Policy Debate in an Era of Welfare Reform.

    ERIC Educational Resources Information Center

    Gleeson, James P.

    1996-01-01

    Presents a case study of the development of kinship care policy in Illinois due to court decisions regarding the provision of financial support to relatives acting as foster parents. Compares recent reform of kinship care policies in Illinois with welfare reform efforts across the country and their national implications. (SD)

  8. Associations between Intensity of Child Welfare Involvement and Child Development among Young Children in Child Welfare

    ERIC Educational Resources Information Center

    Stahmer, Aubyn C.; Hurlburt, Michael; Horwitz, Sarah McCue; Landsverk, John; Zhang, Jinjin; Leslie, Laurel K.

    2009-01-01

    Objective: To examine developmental and behavioral status of children in child welfare (CW) over time, by intensity of CW involvement using a national probability sample. Methods: As part of the National Survey of Child and Adolescent Well-being (NSCAW), data were collected on 1,049 children 12-47 months old investigated by CW agencies for

  9. Racial and Spatial Equity in Welfare Programs: Interstate and Intercounty Differences in Welfare Spending.

    ERIC Educational Resources Information Center

    Nord, Mark

    1999-01-01

    States where a large proportion of the poor are rural residents or racial/ethnic minorities provided less welfare support per poor child under Aid to Families with Dependent Children than did other states. No corresponding rural or racial/ethnic disadvantage was observed for the Food Stamp program, which has nationwide eligibility criteria and

  10. Animal welfare and developing countries: opportunities for trade in high-welfare products from developing countries.

    PubMed

    Bowles, D; Paskin, R; Gutirrez, M; Kasterine, A

    2005-08-01

    Discussion on the potential for developing countries to develop trade in niche markets such as higher welfare standards has been highlighted with moves by the World Organisation for Animal Health (OIE) to set internationally agreed standards for animal welfare. This paper examines the existing and potential trade in value-added higher welfare products using case studies in the beef and poultry sectors from three countries in Africa, Asia and Latin America. It shows that at present there is only a small trade in these products but that this can have a major effect at a national level. In the beef export trade from Namibia, the existence of the only assurance scheme in Africa setting standards in hygiene, veterinary care and animal welfare has created a trusted, safe and healthy product and ensured that Namibia has grown into Africa's largest exporter of beef to the European Union. In Thailand, the broiler industry, which has enjoyed annual growth in the past 15 years, is developing value-added products to develop markets to counter competition from other countries. The development and implementation of standards for organic products in both Thailand and Argentina over the past decade have also resulted in growth in the export markets of these products. The paper concludes that there is growth potential for the sectors in all three markets which can be assisted by the development of OIE baseline standards. PMID:16358527

  11. Organization of the bacterial chromosome.

    PubMed Central

    Krawiec, S; Riley, M

    1990-01-01

    Recent progress in studies on the bacterial chromosome is summarized. Although the greatest amount of information comes from studies on Escherichia coli, reports on studies of many other bacteria are also included. A compilation of the sizes of chromosomal DNAs as determined by pulsed-field electrophoresis is given, as well as a discussion of factors that affect gene dosage, including redundancy of chromosomes on the one hand and inactivation of chromosomes on the other hand. The distinction between a large plasmid and a second chromosome is discussed. Recent information on repeated sequences and chromosomal rearrangements is presented. The growing understanding of limitations on the rearrangements that can be tolerated by bacteria and those that cannot is summarized, and the sensitive region flanking the terminator loci is described. Sources and types of genetic variation in bacteria are listed, from simple single nucleotide mutations to intragenic and intergenic recombinations. A model depicting the dynamics of the evolution and genetic activity of the bacterial chromosome is described which entails acquisition by recombination of clonal segments within the chromosome. The model is consistent with the existence of only a few genetic types of E. coli worldwide. Finally, there is a summary of recent reports on lateral genetic exchange across great taxonomic distances, yet another source of genetic variation and innovation. PMID:2087223

  12. SEX CHROMOSOMES IN FLOWERING PLANTS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sex chromosomes in dioecious and polygamous plants evolved as a mechanism for ensuring outcrossing to increase genetic variation in the offspring. Sex specificity has evolved in 75% of plant families by male sterile or female sterile mutations, but well defined heteromorphic sex chromosomes are know...

  13. Cohesin in determining chromosome architecture

    SciTech Connect

    Haering, Christian H.; Jessberger, Rolf

    2012-07-15

    Cells use ring-like structured protein complexes for various tasks in DNA dynamics. The tripartite cohesin ring is particularly suited to determine chromosome architecture, for it is large and dynamic, may acquire different forms, and is involved in several distinct nuclear processes. This review focuses on cohesin's role in structuring chromosomes during mitotic and meiotic cell divisions and during interphase.

  14. Conflicting and complementary ethics of animal welfare considerations in reintroductions.

    PubMed

    Harrington, Lauren A; Moehrenschlager, Axel; Gelling, Merryl; Atkinson, Rob P D; Hughes, Joelene; Macdonald, David W

    2013-06-01

    Despite differences in focus, goals, and strategies between conservation biology and animal welfare, both are inextricably linked in many ways, and greater consideration of animal welfare, although important in its own right, also has considerable potential to contribute to conservation success. Nevertheless, animal welfare and animal ethics are not always considered explicitly within conservation practice. We systematically reviewed the recent scientific peer-reviewed and online gray literature on reintroductions of captive-bred and wild-caught animals (mammals, birds, amphibians, and reptiles) to quantify the occurrence of animal welfare issues. We considered monitoring that could be indicative of the animal's welfare status and supportive management actions that could improve animal welfare (regardless of whether the aim was explicitly animal-welfare orientated). Potential welfare issues (of variable nature and extent) were recorded in 67% of 199 projects reviewed; the most common were mortality >50%, dispersal or loss of animals, disease, and human conflict. Most (>70%) projects monitored survival, 18% assessed body condition, and 2% monitored stress levels. Animal welfare, explicitly, was referred to in 6% of projects. Supportive actions, most commonly use of on-site prerelease pens and provision of supplemental food or water, were implemented in 79% of projects, although the extent and duration of support varied. Practitioners can address animal-welfare issues in reintroductions by considering the potential implications for individual animals at all stages of the release process using the decision tree presented. We urge practitioners to report potential animal-welfare issues, describe mitigation actions, and evaluate their efficacy to facilitate transparent evaluation of common moral dilemmas and to advance communal strategies for dealing with them. Currently, comparative mortality rates, health risks, postrelease stress, effectiveness of supportive measures, and behavior of individuals warrant further research to improve animal welfare in reintroductions and to increase success of such projects. PMID:23506045

  15. Influences of Maternal Care on Chicken Welfare.

    PubMed

    Edgar, Joanne; Held, Suzanne; Jones, Charlotte; Troisi, Camille

    2016-01-01

    In domestic chickens, the provision of maternal care strongly influences the behavioural development of chicks. Mother hens play an important role in directing their chicks' behaviour and are able to buffer their chicks' response to stressors. Chicks imprint upon their mother, who is key in directing the chicks' behaviour and in allowing them to develop food preferences. Chicks reared by a mother hen are less fearful and show higher levels of behavioural synchronisation than chicks reared artificially. In a commercial setting, more fearful chicks with unsynchronised behaviour are more likely to develop behavioural problems, such as feather pecking. As well as being an inherent welfare problem, fear can also lead to panic responses, smothering, and fractured bones. Despite the beneficial effects of brooding, it is not commercially viable to allow natural brooding on farms and so chicks are hatched in large incubators and reared artificially, without a mother hen. In this review we cover the literature demonstrating the important features of maternal care in domestic chickens, the behavioural consequences of deprivation and the welfare implications on commercial farms. We finish by suggesting ways to use research in natural maternal care to improve commercial chick rearing practice. PMID:26742081

  16. Welfare and the intensive production of rabbits.

    PubMed

    Morisse, J P; Maurice, R

    1994-03-01

    Rabbit production in Europe is concentrated largely in the "Latin" countries of Italy, France and Spain, in which animal protectionist attitudes are considered moderate. However, in the case of rabbits, the intensification of husbandry necessitates strict observance of physiological, behavioural and health requirements, in view of the very special needs of the species and the sensitivity of rabbits to environmental conditions. Rabbits are described as anxious, timid and emotional, with unusual arrangements for reproduction (induced ovulation) and digestion (caecotrophy). Therefore, these animals could not be reared intensively until the completion of extensive research, which has been conducted over the past twenty years, into the environmental and nutritional needs of rabbits, and the selection of lines having a calm temperament and maternal aptitude. This research was required to meet the welfare needs of this species. These concepts are perfectly integrated into the current operation of intensive units, and should not be brought into question on the basis of fragmentary observations by some researchers who would wish to see a return to rearing on litter. A discussion of rabbit welfare conducted in 1992 by specialists of the German branch of the World Rabbit Science Association approved modern methods of keeping rabbits on wire grids, provided that some changes were made to current procedures. PMID:8173093

  17. Welfare, women, and families: implications for clinicians.

    PubMed

    Smith, Lauren A

    2002-01-01

    Although the 1996 welfare reform law signaled a most profound shift in US social policy, clinicians do not fully appreciate the potential impact this legislation could have on patterns of health and the provision of health services to millions of American women and children. The data presented in this issue of JAMWA point to definitive steps clinicians can take to provide optimal care for their patients. First, we must commit to educating ourselves and others who care for patients about the nature and potential impact of welfare reform. Second, we must devise efficient and effective ways of identifying and addressing these needs in our clinical settings. Third, clinicians should use their experience to effectively advocate for their patients on individual and population levels. As clinicians, we have no choice but to respond to the social forces that so profoundly affect the health of the families we serve; we must take advantage of our capacity to make substantial contributions to the health and well-being of our patients. PMID:11905495

  18. Bacterial Chromosome Organization and Segregation.

    PubMed

    Badrinarayanan, Anjana; Le, Tung B K; Laub, Michael T

    2015-11-13

    If fully stretched out, a typical bacterial chromosome would be nearly 1 mm long, approximately 1,000 times the length of a cell. Not only must cells massively compact their genetic material, but they must also organize their DNA in a manner that is compatible with a range of cellular processes, including DNA replication, DNA repair, homologous recombination, and horizontal gene transfer. Recent work, driven in part by technological advances, has begun to reveal the general principles of chromosome organization in bacteria. Here, drawing on studies of many different organisms, we review the emerging picture of how bacterial chromosomes are structured at multiple length scales, highlighting the functions of various DNA-binding proteins and the impact of physical forces. Additionally, we discuss the spatial dynamics of chromosomes, particularly during their segregation to daughter cells. Although there has been tremendous progress, we also highlight gaps that remain in understanding chromosome organization and segregation. PMID:26566111

  19. Schizophrenia and chromosomal deletions

    SciTech Connect

    Lindsay, E.A.; Baldini, A.; Morris, M. A.

    1995-06-01

    Recent genetic linkage analysis studies have suggested the presence of a schizophrenia locus on the chromosomal region 22q11-q13. Schizophrenia has also been frequently observed in patients affected with velo-cardio-facial syndrome (VCFS), a disorder frequently associated with deletions within 22q11.1. It has been hypothesized that psychosis in VCFS may be due to deletion of the catechol-o-methyl transferase gene. Prompted by these observations, we screened for 22q11 deletions in a population of 100 schizophrenics selected from the Maryland Epidemiological Sample. Our results show that there are schizophrenic patients carrying a deletion of 22q11.1 and a mild VCFS phenotype that might remain unrecognized. These findings should encourage a search for a schizophrenia-susceptibility gene within the deleted region and alert those in clinical practice to the possible presence of a mild VCFS phenotype associated with schizophrenia. 9 refs.

  20. Chromosome preparation from cultured cells.

    PubMed

    Howe, Bradley; Umrigar, Ayesha; Tsien, Fern

    2014-01-01

    Chromosome (cytogenetic) analysis is widely used for the detection of chromosome instability. When followed by G-banding and molecular techniques such as fluorescence in situ hybridization (FISH), this assay has the powerful ability to analyze individual cells for aberrations that involve gains or losses of portions of the genome and rearrangements involving one or more chromosomes. In humans, chromosome abnormalities occur in approximately 1 per 160 live births(1,2), 60-80% of all miscarriages(3,4), 10% of stillbirths(2,5), 13% of individuals with congenital heart disease(6), 3-6% of infertility cases(2), and in many patients with developmental delay and birth defects(7). Cytogenetic analysis of malignancy is routinely used by researchers and clinicians, as observations of clonal chromosomal abnormalities have been shown to have both diagnostic and prognostic significance(8,9). Chromosome isolation is invaluable for gene therapy and stem cell research of organisms including nonhuman primates and rodents(10-13). Chromosomes can be isolated from cells of live tissues, including blood lymphocytes, skin fibroblasts, amniocytes, placenta, bone marrow, and tumor specimens. Chromosomes are analyzed at the metaphase stage of mitosis, when they are most condensed and therefore more clearly visible. The first step of the chromosome isolation technique involves the disruption of the spindle fibers by incubation with Colcemid, to prevent the cells from proceeding to the subsequent anaphase stage. The cells are then treated with a hypotonic solution and preserved in their swollen state with Carnoy's fixative. The cells are then dropped on to slides and can then be utilized for a variety of procedures. G-banding involves trypsin treatment followed by staining with Giemsa to create characteristic light and dark bands. The same procedure to isolate chromosomes can be used for the preparation of cells for procedures such as fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), and spectral karyotyping (SKY)(14,15). PMID:24513647

  1. X-Chromosome dosage compensation.

    PubMed Central

    Meyer, Barbara J

    2005-01-01

    In mammals, flies, and worms, sex is determined by distinctive regulatory mechanisms that cause males (XO or XY) and females (XX) to differ in their dose of X chromosomes. In each species, an essential X chromosome-wide process called dosage compensation ensures that somatic cells of either sex express equal levels of X-linked gene products. The strategies used to achieve dosage compensation are diverse, but in all cases, specialized complexes are targeted specifically to the X chromosome(s) of only one sex to regulate transcript levels. In C. elegans, this sex-specific targeting of the dosage compensation complex (DCC) is controlled by the same developmental signal that establishes sex, the ratio of X chromosomes to sets of autosomes (X:A signal). Molecular components of this chromosome counting process have been defined. Following a common step of regulation, sex determination and dosage compensation are controlled by distinct genetic pathways. C. elegans dosage compensation is implemented by a protein complex that binds both X chromosomes of hermaphrodites to reduce transcript levels by one-half. The dosage compensation complex resembles the conserved 13S condensin complex required for both mitotic and meiotic chromosome resolution and condensation, implying the recruitment of ancient proteins to the new task of regulating gene expression. Within each C. elegans somatic cell, one of the DCC components also participates in the separate mitotic/meiotic condensin complex. Other DCC components play pivotal roles in regulating the number and distribution of crossovers during meiosis. The strategy by which C. elegans X chromosomes attract the condensin-like DCC is known. Small, well-dispersed X-recognition elements act as entry sites to recruit the dosage compensation complex and to nucleate spreading of the complex to X regions that lack recruitment sites. In this manner, a repressed chromatin state is spread in cis over short or long distances, thus establishing the global, epigenetic regulation of X chromosomes that is maintained throughout the lifetime of hermaphrodites. PMID:18050416

  2. Chromosome Preparation From Cultured Cells

    PubMed Central

    Howe, Bradley; Umrigar, Ayesha; Tsien, Fern

    2014-01-01

    Chromosome (cytogenetic) analysis is widely used for the detection of chromosome instability. When followed by G-banding and molecular techniques such as fluorescence in situ hybridization (FISH), this assay has the powerful ability to analyze individual cells for aberrations that involve gains or losses of portions of the genomeand rearrangements involving one or more chromosomes. In humans, chromosome abnormalities occur in approximately 1 per 160 live births1,2, 60-80% of all miscarriages3,4, 10% of stillbirths2,5, 13% of individuals with congenital heart disease6, 3-6% of infertility cases2, and in many patients with developmental delayand birth defects7. Cytogenetic analysis of malignancy is routinely used by researchers and clinicians, as observations of clonal chromosomal abnormalities have been shown to have both diagnostic and prognostic significance8,9. Chromosome isolation is invaluable for gene therapy and stem cell research of organisms including nonhuman primates and rodents10-13. Chromosomes can be isolated from cells of live tissues, including blood lymphocytes, skin fibroblasts, amniocytes, placenta, bone marrow, and tumor specimens. Chromosomes are analyzed at the metaphase stage of mitosis, when they are most condensed and therefore more clearly visible. The first step of the chromosome isolation technique involves the disruption of the spindle fibers by incubation with Colcemid, to prevent the cells from proceeding to the subsequent anaphase stage. The cells are then treated with a hypotonic solution and preserved in their swollen state with Carnoy's fixative. The cells are then dropped on to slides and can then be utilized for a variety of procedures. G-banding involves trypsin treatment followed by staining with Giemsa to create characteristic light and dark bands. The same procedure to isolate chromosomes can be used for the preparation of cells for procedures such as fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), and spectral karyotyping (SKY)14,15. PMID:24513647

  3. Chromosomal analysis of blastocysts from balanced chromosomal rearrangement carriers.

    PubMed

    Gui, Baoheng; Yao, Zhongyuan; Li, Yanping; Liu, Donge; Liu, Nenghui; Xia, Yan; Huang, Yanru; Mei, Libin; Ma, Ruiyu; Lu, Sijia; Liang, Desheng; Wu, Lingqian

    2016-04-01

    Balanced chromosomal rearrangements (CRs) are among the most common genetic abnormalities in humans. In the present study, we have investigated the degree of consistency between the chromosomal composition of the blastocyst inner cell mass (ICM) and trophectoderm (TE) in carriers with balanced CR, which has not been previously addressed. As a secondary aim, we have also evaluated the validity of cleavage-stage preimplantation genetic diagnosis (PGD) based on fluorescence in situ hybridization (FISH) of blastocysts from CR carriers. Blastocyst ICM and TE were screened for chromosomal aneuploidy and imbalance of CR-associated chromosomes based on whole-genome copy number variation analysis by low-coverage next-generation sequencing (NGS) following single-cell whole-genome amplification by multiple annealing and looping-based amplification cycling. The NGS results were analyzed without knowledge of cleavage-stage FISH results. NGS results for blastocyst ICM and TE from CR carriers were 86.49% (32/37) consistent. Of the 1702 (37×46) chromosomes examined, 99.47% (1693/1702) showed consistency. However, only 40.0% (18/45) of all embryos had consistent results for chromosomes involved in CR, as determined by blastocyst NGS and cleavage-stage FISH. Of the 85 CR-affected chromosomes analyzed by FISH, 37.65% (32/85) were incongruous with NGS results, with 87.5% (28/32) showing imbalanced composition by FISH but balanced composition by NGS. These results indicate that chromosomal composition of blastocyst ICM and TE in balanced CR carriers is highly consistent, and that PGD based on cleavage-stage FISH is inaccurate; therefore, using blastocyst TE biopsies for NGS-based PGD is recommended for identifying chromosomal imbalance in embryos from balanced CR carriers. PMID:26825930

  4. Genetics Home Reference: Ring chromosome 20 syndrome

    MedlinePLUS

    ... help with understanding ring chromosome 20 syndrome? cell ; cell division ; chromosome ; disability ; embryonic ; epilepsy ; epileptic ; gene ; inherited ; microcephaly ; mosaicism ; prevalence ; reproductive ...

  5. Mitotic chromosome condensation in vertebrates

    SciTech Connect

    Vagnarelli, Paola

    2012-07-15

    Work from several laboratories over the past 10-15 years has revealed that, within the interphase nucleus, chromosomes are organized into spatially distinct territories [T. Cremer, C. Cremer, Chromosome territories, nuclear architecture and gene regulation in mammalian cells, Nat. Rev. Genet. 2 (2001) 292-301 and T. Cremer, M. Cremer, S. Dietzel, S. Muller, I. Solovei, S. Fakan, Chromosome territories-a functional nuclear landscape, Curr. Opin. Cell Biol. 18 (2006) 307-316]. The overall compaction level and intranuclear location varies as a function of gene density for both entire chromosomes [J.A. Croft, J.M. Bridger, S. Boyle, P. Perry, P. Teague,W.A. Bickmore, Differences in the localization and morphology of chromosomes in the human nucleus, J. Cell Biol. 145 (1999) 1119-1131] and specific chromosomal regions [N.L. Mahy, P.E. Perry, S. Gilchrist, R.A. Baldock, W.A. Bickmore, Spatial organization of active and inactive genes and noncoding DNA within chromosome territories, J. Cell Biol. 157 (2002) 579-589] (Fig. 1A, A'). In prophase, when cyclin B activity reaches a high threshold, chromosome condensation occurs followed by Nuclear Envelope Breakdown (NEB) [1]. At this point vertebrate chromosomes appear as compact structures harboring an attachment point for the spindle microtubules physically recognizable as a primary constriction where the two sister chromatids are held together. The transition from an unshaped interphase chromosome to the highly structured mitotic chromosome (compare Figs. 1A and B) has fascinated researchers for several decades now; however a definite picture of how this process is achieved and regulated is not yet in our hands and it will require more investigation to comprehend the complete process. From a biochemical point of view a vertebrate mitotic chromosomes is composed of DNA, histone proteins (60%) and non-histone proteins (40%) [6]. I will discuss below what is known to date on the contribution of these two different classes of proteins and their co-operation in establishing the final mitotic chromosome structure.

  6. Common NICU Equipment

    MedlinePLUS

    ... added to your dashboard . The NICU contains many machines and other types of equipment used to care for sick babies with many different problems. These machines seem less intimidating when you understand how they ...

  7. Magnetotelluric Equipment Installation

    USGS Multimedia Gallery

    USGS scientist, Jared Peacock making sure the equipment is set up properly with good data coming in, and programming the data logger to collect magnetotelluric data for 24 hours as NAGT intern, Monica Mustain looks on....

  8. Selecting Library Furniture & Equipment.

    ERIC Educational Resources Information Center

    Media & Methods, 1997

    1997-01-01

    Offers suggestions for selecting school library furniture and equipment. Describes various models of computer workstations; reading tables and chairs; and shelving. Sidebar lists names and addresses of library furniture manufactures and distributors. (AEF)

  9. Equipment & New Products.

    ERIC Educational Resources Information Center

    Poitras, Adrian W., Ed.

    1979-01-01

    Reviews new science equipment and products for the laboratory. Includes hand-held calculators, fiberglass fume hoods, motorized microtomy, disposable mouse cages, and electric timers. Describes 11 products total. Provides manufacturer name, address, and price. (MA)

  10. Cleaning supplies and equipment

    MedlinePLUS

    ... something means to clean it to destroy germs. Disinfectants are the cleaning solutions that are used to ... each solution. You may need to allow the disinfectant to dry on the equipment for a set ...

  11. The Supply Chain’s Role in Improving Animal Welfare

    PubMed Central

    Harvey, David; Hubbard, Carmen

    2013-01-01

    Simple Summary The ability of supply chains to deliver high(er) levels and standards of animal welfare is subject to two critical conditions: (a) the innovative and adaptive capacity of actors in the chain to respond to society’s demands; (b) consumers actually buying animal-friendly products. Unless citizens are willing to support suppliers who comply with high(er) standards, their votes for better animal welfare risk exporting poor animal welfare to other countries with less rigorous standards. The logic of market failure in the case of animal welfare points to the superiority of consumer subsidies over producer subsidies to deliver improved animal welfare. Abstract Supply chains are already incorporating citizen/consumer demands for improved animal welfare, especially through product differentiation and the associated segmentation of markets. Nonetheless, the ability of the chain to deliver high(er) levels and standards of animal welfare is subject to two critical conditions: (a) the innovative and adaptive capacity of the chain to respond to society’s demands; (b) the extent to which consumers actually purchase animal-friendly products. Despite a substantial literature reporting estimates of willingness to pay (WTP) for animal welfare, there is a belief that in practice people vote for substantially more and better animal welfare as citizens than they are willing to pay for as consumers. This citizen-consumer gap has significant consequences on the supply chain, although there is limited literature on the capacity and willingness of supply chains to deliver what the consumer wants and is willing to pay for. This paper outlines an economic analysis of supply chain delivery of improved standards for farm animal welfare in the EU and illustrates the possible consequences of improving animal welfare standards for the supply chain using a prototype belief network analysis. PMID:26479533

  12. Drivers for animal welfare policies in the Middle East.

    PubMed

    Aidaros, H

    2014-04-01

    Religion, ethics and culture are an important group of drivers for animal welfare policies in the Middle East. In many countries of the region the understanding of animal welfare is expressed more in terms of religious precepts and humane ethics than via regulations and legislation. In fact, regulatory and legislated animal welfare standards are still not well implemented and many animal welfare issues require attention. The Qur'an provides considerable support for conscientiously attending to animal welfare. For example, the Islamic rules on the process of slaughter were intended to provide a quick, humane and relatively painless death. Current practices that are not in accordance with these religious teachings may cause great suffering to animals. Although these rules have been in place for 1,400 years or more, now, in the 21st Century, they are found to closely correspond to the related standards of the World Organisation for Animal Health (OIE). The OIE plays an important role in improving animal welfare by developing global animal welfare standards. These should assist countries in two important ways: first, by helping them to establish new, or to refine existing, animal welfare legislation, and second, at the OIE regional level, by facilitating interactions between Member Countries as they develop and refine a strategic plan for the advancement of animal welfare. As the OIE standards are compatible with the requirements of Islamic law, issuing animal welfare legislation referring to those standards and implementing them at a national level is highly recommended. A dialogue between the OIE and the Veterinary Services and religious leaders in the region should therefore start with the objective of improving animal welfare. PMID:25000780

  13. Medicine As a Corporate Enterprise, Patient Welfare Centered Profession, or Patient Welfare Centered Professional Enterprise?

    PubMed Central

    Singh, Ajai; Singh, Shakuntala

    2005-01-01

    There is an alarming trend in the field of medicine, whose portents are ominous but do not seem to shake the complacency and merry making doing the rounds. The wants of the medical man have multiplied beyond imagination. The cost of organizing conferences is no longer possible on delegate fees. The bottom-line is: Crores for a Conference Millions for a Mid-Term. However, the problem is that sponsors keep a discreet but careful tab on docs. All in all, costs of medicines escalate, and quality medical care becomes a luxury. The whole brunt of this movement is borne by the patient. Companies like GlaxoSmithKline, Bayer, Pfizer, Bristol-Myers Squibb, AstraZeneca, Schering-Plough, Abbott Labs, TAP Pharmaceuticals, Wyeth and Merck have paid millions of dollars each as compensation in the last few years. The financial condition of many pharmaceutical majors is not buoyant either. Price deflation, increased Rand D spending, and litigation costs are the main reasons. In the future, the messy lawsuits situation would no longer be restricted to industry. It would involve academia and practising doctors as well. Indian pharma industry captains, who were busy raking in the profits at present, would also come under the scanner. If nothing else, it means industry and docs will have to sit down and do some soul searching. Both short and long-term measures will have to be put into place. Short-term measures involve reduction in i) pharma spending over junkets and trinkets; ii) hype over me too drugs; iii) manipulation of drug trials; iv) getting pliant researchers into drug trials; iv) manipulation of Journal Editors to publish positive findings about their drug trials and launches; v) and for Indian Pharma, to conduct their own unbiased clinical trial of the latest drug projected as a blockbuster in the West, before pumping in their millions. The long-term measures are related to the way biomedical advance is to be charted. We have to decide whether medicine is to become a corporate enterprise or remain a patient welfare centered profession. A third approach involves an eclectic resolution of the two. Such amount of patient welfare as also ensures profit, and such amount of profit as also ensures patient welfare is to be forwarded. For, profit, without patient welfare, is blind. And patient welfare, without profit, is lame. According to this approach, medicine becomes a patient welfare centered professional enterprise. The various ramifications of each of these approaches are discussed in this monograph. PMID:22679354

  14. A chromosome 11 YAC library

    SciTech Connect

    Qin, S.; Zhang, J.; Isaacs, C.M.; Nagafuchi, S.; Jani Sait, S.N.; Abel, K.J.; Higgins, M.J.; Nowak, N.J.; Shows, T.B. )

    1993-06-01

    A targeted yeast artificial chromosome (YAC) library for chromosome 11 has been constructed from the J1 cell line that carries a single human chromosome 11 within a hamster DNA background. Interspecies chimeric clones generated during construction of the library were detected during the screening process and eliminated from the library. Contig assembly becomes much less difficult using such a library as the complexity is decreased and the ends of the clone inserts can be rescued for walking to neighboring clones. The library contains > 1824 clones with an average insert length of 337 kb. This represents a fourfold coverage of chromosome 11 or a >95% chance of recovering a unique single-copy sequence from the library. Two hundred YAC clones were localized by fluorescence in situ hybridization and found to be randomly distributed along the chromosome. The library has been screened with probes for the chromosome 11 markers HBB, GLUR4, H19, and D11S193. Corresponding YAC clones have been isolated for each locus. This analysis has indicated that the library is unbiased, that cognate YAC clones can be recovered with chromosome 11 markers, and that extensive contig assembly should be feasible. 31 refs., 5 figs.

  15. Chromosome specific repetitive DNA sequences

    DOEpatents

    Moyzis, Robert K.; Meyne, Julianne

    1991-01-01

    A method is provided for determining specific nucleotide sequences useful in forming a probe which can identify specific chromosomes, preferably through in situ hybridization within the cell itself. In one embodiment, chromosome preferential nucleotide sequences are first determined from a library of recombinant DNA clones having families of repetitive sequences. Library clones are identified with a low homology with a sequence of repetitive DNA families to which the first clones respectively belong and variant sequences are then identified by selecting clones having a pattern of hybridization with genomic DNA dissimilar to the hybridization pattern shown by the respective families. In another embodiment, variant sequences are selected from a sequence of a known repetitive DNA family. The selected variant sequence is classified as chromosome specific, chromosome preferential, or chromosome nonspecific. Sequences which are classified as chromosome preferential are further sequenced and regions are identified having a low homology with other regions of the chromosome preferential sequence or with known sequences of other family me This invention is the result of a contract with the Department of Energy (Contract No. W-7405-ENG-36).

  16. Anaesthesia of farmed fish: implications for welfare.

    PubMed

    Zahl, Inger Hilde; Samuelsen, Ole; Kiessling, Anders

    2012-02-01

    During their life cycle as farmed animals, there are several situations in which fish are subjected to handling and confinement. Netting, weighing, sorting, vaccination, transport and, at the end, slaughter are frequent events under farming conditions. As research subjects, fish may also undergo surgical procedures that range from tagging, sampling and small incisions to invasive procedures. In these situations, treatment with anaesthetic agents may be necessary in order to ensure the welfare of the fish. The main objective of this paper is to review our knowledge of the effects of anaesthetic agents in farmed fish and their possible implications for welfare. As wide variations in response to anaesthesia have been observed both between and within species, special attention has been paid to the importance of secondary factors such as body weight, water temperature and acute stress. In this review, we have limited ourselves to the anaesthetic agents such as benzocaine, metacaine (MS-222), metomidate hydrochloride, isoeugenol, 2-phenoxyethanol and quinaldine. Anaesthetic protocols of fish usually refer to one single agent, whereas protocols of human and veterinary medicine cover combinations of several drugs, each contributing to the effects needed in the anaesthesia. As stress prior to anaesthesia may result in abnormal reactions, pre-anaesthetic sedation is regularly used in order to reduce or avoid stress and is an integral part of the veterinary protocols of higher vertebrates. Furthermore, the anaesthetic agents that are used in order to obtain general anaesthesia are combined with analgesic agents that target nociception. The increased use of such combinations in fish is therefore included as a special section. Anaesthetic agents are widely used to avoid stress during various farming procedures. While several studies report that anaesthetics are effective in reducing the stress associated with confinement and handling, there are indications that anaesthesia may in itself induce a stress response, measured by elevated levels of cortisol. MS-222 has been reported to elicit high cortisol release rates immediately following exposure, while benzocaine causes a bimodal response. Metomidate has an inhibitory effect on cortisol in fish and seems to induce the lowest release of cortisol of the agents reported in the literature. Compared to what is observed following severe stressors such as handling and confinement, the amount of cortisol released in response to anaesthesia appears to be low but may represent an extra load under otherwise stressful circumstances. Furthermore, anaesthetics may cause secondary adverse reactions such as acidosis and osmotic stress due to respiratory arrest and insufficient exchange of gas and ions between the blood and the water. All in all, anaesthetics may reduce stress and thereby improve welfare but can also have unwanted side effects that reduce the welfare of the fish and should therefore always be used with caution. Finally, on the basis of the data reported in the literature and our own experience, we recommend that anaesthetic protocols should always be tested on a few fish under prevailing conditions in order to ensure an adequate depth of anaesthesia. This recommendation applies whether a single agent or a combination of agents is used, although it appears that protocols comprising combinations of agents provide wider safety margins. The analgesic effects of currently used agents, in spite of their proven local effects, are currently being debated as the agents are administrated to fish via inhalation rather than locally at the target site. We therefore recommend that all protocols of procedures requiring general anaesthesia should be complemented by administration of agents with analgesic effect at the site of tissue trauma. PMID:22160749

  17. An animal welfare view of wildlife contraception.

    PubMed

    Grandy, J W; Rutberg, A T

    2002-01-01

    Although there is some dissent, the animal protection community generally supports the concept of wildlife contraception. However, some contraceptive agents, delivery mechanisms and specific applications will be opposed by animal welfare advocates on environmental, humane or other ethical grounds, and some animal rights advocates may oppose wildlife contraception entirely. The Humane Society of the United States (HSUS) has supported and conducted wildlife contraception studies for more than 10 years. In general, we have invested in contraceptive agents (such as porcine zona pellucida) that we believe will prove environmentally, physiologically and behaviourally benign, and in delivery mechanisms that are narrowly targeted. As we consider contraception to be a major intervention into natural processes, we believe that wildlife contraception should be applied judiciously, locally and in a manner that is sensitive to the needs of animals, humans and ecosystem function. PMID:12220149

  18. 45 CFR 84.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Health, welfare, and other social services. 84.52..., Welfare, and Social Services 84.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits, a recipient may not, on the basis of handicap:...

  19. 45 CFR 605.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Health, welfare, and other social services. 605.52 Section 605.52 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and...

  20. 45 CFR 605.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Health, welfare, and other social services. 605.52 Section 605.52 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and...

  1. 45 CFR 84.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Health, welfare, and other social services. 84.52..., Welfare, and Social Services 84.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits, a recipient may not, on the basis of handicap:...

  2. 45 CFR 84.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Health, welfare, and other social services. 84.52..., Welfare, and Social Services 84.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits, a recipient may not, on the basis of handicap:...

  3. 45 CFR 84.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Health, welfare, and other social services. 84.52..., Welfare, and Social Services 84.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits, a recipient may not, on the basis of handicap:...

  4. Analysis of chromosome 21 yeast artificial chromosome (YAC) clones

    SciTech Connect

    Tassone, F. A. Gemelli School of Medicine, Rome ); Cheng, S.; Gardiner, K. )

    1992-12-01

    Chromosome 21 contains genes relevant to several important diseases. Yeast artificial chromosome (YAC) clones, because they span >100 kbp, will provide attractive material for initiating searches for such genes. Twenty-two YAC clones, each of which maps to a region of potential relevance either to aspects of the Down syndrome phenotype or to one of the other chromosome 21-associated genetic diseases, have been analyzed in detail. Clones total [approximately]6,000 kb and derive from all parts of the long arm. Rare restriction-site maps have been constructed for each clone and have been used to determine regional variations in clonability, methylation frequency, CpG island density, and CpG island frequency versus gene density. This information will be useful for the isolation and mapping of new genes to chromosome 21 and for walking in YAC libraries. 48 refs., 3 figs., 4 tabs.

  5. Family planning offered in local welfare offices.

    PubMed

    1998-04-01

    This article describes expanded access to family planning (FP) services through community welfare offices in Washington state, US. The government aim is to decrease unintended pregnancies and to help families achieve self-sufficiency. The staff must be sensitive and respectful of clients served. The team effort includes contacting clients in other community locations to offer FP education. The approach is characterized as "1-stop shopping" that includes FP, welfare, access to jobs, training, and medical coupons. Preventing unintended pregnancies is cost effective. A state (90%) investment of $40/person for contraceptives is good business compared to $400/person as a 50/50 state/federal investment in prenatal and delivery costs. The program began in 1992, by educating staff members in community services offices (CSOs) about FP issues. In 1994, the program hired registered nurses and nurse practitioners at CSOs to provide FP services. Almost all CSOs now have nurses, and there are 8 full exam clinics. A resource handbook for CSO workers and FP nurses was compiled by state and local FP personnel. CSOs typically assign 1 staff member to FP, usually on a part time basis. Close collaboration between nurses and CSO workers usually involves more creative strategies and outreach projects. For example, in 1 CSO in Washington, the FP worker offers contraceptive counseling, pregnancy tests, and sexually transmitted disease prevention. Contraceptives are provided at a separate time with local private providers or at health department clinics. CSOs continue to provide counseling regardless of referrals to private clinics. The project is growing and forming collaborations with other FP groups. These 1-stop sites offer accessible, familiar, and comfortable services. PMID:12293169

  6. Numerous Transitions of Sex Chromosomes in Diptera

    PubMed Central

    Vicoso, Beatriz; Bachtrog, Doris

    2015-01-01

    Many species groups, including mammals and many insects, determine sex using heteromorphic sex chromosomes. Diptera flies, which include the model Drosophila melanogaster, generally have XY sex chromosomes and a conserved karyotype consisting of six chromosomal arms (five large rods and a small dot), but superficially similar karyotypes may conceal the true extent of sex chromosome variation. Here, we use whole-genome analysis in 37 fly species belonging to 22 different families of Diptera and uncover tremendous hidden diversity in sex chromosome karyotypes among flies. We identify over a dozen different sex chromosome configurations, and the small dot chromosome is repeatedly used as the sex chromosome, which presumably reflects the ancestral karyotype of higher Diptera. However, we identify species with undifferentiated sex chromosomes, others in which a different chromosome replaced the dot as a sex chromosome or in which up to three chromosomal elements became incorporated into the sex chromosomes, and others yet with female heterogamety (ZW sex chromosomes). Transcriptome analysis shows that dosage compensation has evolved multiple times in flies, consistently through up-regulation of the single X in males. However, X chromosomes generally show a deficiency of genes with male-biased expression, possibly reflecting sex-specific selective pressures. These species thus provide a rich resource to study sex chromosome biology in a comparative manner and show that similar selective forces have shaped the unique evolution of sex chromosomes in diverse fly taxa. PMID:25879221

  7. Listing of Food Service Equipment.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI. Testing Lab.

    A comprehensive listing of food service equipment including--(1) companies authorized to use the National Sanitation Foundation seal of approval, and (2) equipment listed as meeting NSF standards including soda fountains, spray-type dishwashers, dishwashing equipment, cooking equipment, commerical cooking and warming equipment, freezers,…

  8. Repetitive telomeric sequences in chromosomal translocations involving chromosome 21

    SciTech Connect

    Qu, J.; Dallaire, L.; Fetni, R.

    1994-09-01

    Telomeres perform key functions in maintaining chromosome integrity. In some structural rearrangements the structure and polymorphism in human telomeres may play a significant role. However, of all the telomeric and subtelomeric sequences, only the terminal TTAGGG repeats are believed essential for telomere function. During the course of a study on the role of telomere structure and polymorphism in chromosomal rearrangements observed in families referred for prenatal diagnosis, we studied three cases in which chromosome 21 was involved. Repetitive TTAGGG sequences for all human chromosomes were used as probes (Oncor). Case 1, a de novo cryptic translocation (2;21) was initially identified as monosomy 21 in a child with psychomotor delay and mild dysmorphism. Using a cosmid probe specific for region 21q22.3 and whole chromosome 21 specific painting probe, the long arm of 21 was found on the short arm of chromosome 2 with an interstitial telomere at the breakpoint junction. All the cells were monosomic for 21pter{yields}q21. Case 2 is a familial (19;21) translocation. GTG-banding and FISH with a satellite probe showed no apparent loss of material at the end of either 19q or 21q, with an interstitial telomere at the fusion site of the two intact chromosomes. In case 3, a four generation reciprocal (20;21) translocation, there was no interstitial telomere. The persistence of an interstitial telomere is a relatively rare event which can now be observed with in situ hybridization. Its study may lead to a better understanding of the dynamics of translocations and of chromosome imbalance.

  9. Indian Child Welfare: A Status Report. Final Report of the Survey of Indian Child Welfare and Implementation of the Indian Child Welfare Act and Section 428 of the Adoption Assistance and Child Welfare Act of 1980.

    ERIC Educational Resources Information Center

    Plantz, Margaret C.; And Others

    This is a report on the first national examination of the effects of the Indian Child Welfare Act (Public Law 95-608), enacted in 1978. The study examines the prevalence of Native American children in substitute care and the implementation of the act and portions of the Adoption Assistance and Child Welfare Act of 1980 as they affect Indian

  10. Depression and Welfare Reform: From Barriers to Inclusion

    ERIC Educational Resources Information Center

    Lewis, Dan A.; Lee, Bong Joo; Altenbernd, Lisa M.

    2006-01-01

    The authors identify ways to facilitate work among current and recent welfare recipients with mental illness. Their analysis assesses the relationship between a particular mental illness, depression, and labor force involvement in a statewide sample of welfare recipients, identifies the factors that promote work for those with depression, and

  11. 20 CFR 638.521 - Student welfare association.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Student welfare association. 638.521 Section 638.521 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Center Operations § 638.521 Student welfare association. The center operator shall...

  12. For Love or Money? Welfare Reform and Immigrant Naturalization

    ERIC Educational Resources Information Center

    Van Hook, Jennifer; Brown, Susan K.; Bean, Frank D.

    2006-01-01

    The Welfare Reform Act of 1996 generally restricted immigrants' eligibility for welfare to those who had naturalized. By increasing the salience of naturalization, the law provides a unique opportunity to examine how social and economic contexts of reception influence immigrants' pursuit of citizenship. This paper summarizes instrumental-legal

  13. Keeping battered women safe during welfare reform: new challenges.

    PubMed

    Raphael, Jody

    2002-01-01

    This paper reviews the growing body of research literature on the relationship of domestic violence to welfare. Not only do women on welfare suffer from domestic violence in far greater numbers than women in the general population, but their abusers, threatened by the women's efforts at education, training, or work, also use violence and threats of violence to sabotage these efforts at economic self-sufficiency. For this reason, welfare reform exacerbates domestic violence in the lives of many low-income women. As a result of the federal Family Violence Option, most state welfare plans allow battered women on welfare more time and specialized services before mandating work in order to keep them and their children safe. Recent research and monitoring have shown, however, that the majority of battered women on welfare do not tell their welfare workers about the violence. Ending the isolation of these battered women and helping them with domestic violence services pose difficult challenges. Women's health providers may be in a better position to accomplish this task than welfare department personnel. PMID:11905488

  14. Child Welfare Services and Delinquency: The Need to Know More

    ERIC Educational Resources Information Center

    Jonson-Reid, Melissa

    2004-01-01

    This article describes the need for a better understanding of the moderating effects of child welfare services on delinquency. Although juvenile delinquency is a commonly studied issue, researchers have paid little attention to the degree to which child welfare services may be associated with changes in subsequent delinquency rates. Emerging

  15. 20 CFR 638.521 - Student welfare association.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Student welfare association. 638.521 Section 638.521 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Center Operations § 638.521 Student welfare association. The center operator shall...

  16. 20 CFR 638.521 - Student welfare association.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Student welfare association. 638.521 Section 638.521 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Center Operations § 638.521 Student welfare association. The center operator shall...

  17. Morbid Obesity and the Transition from Welfare to Work

    ERIC Educational Resources Information Center

    Cawley, John; Danziger, Sheldon

    2005-01-01

    This paper utilizes a rich longitudinal data set--the Women's Employment Study (WES)--to investigate whether obesity, which is common among women of low socioeconomic status, is a barrier to employment and earnings for current and former welfare recipients. We find that former welfare recipients who are both White and morbidly obese have been less

  18. Supporting Child Welfare Supervisors to Improve Worker Retention

    ERIC Educational Resources Information Center

    Landsman, Miriam

    2007-01-01

    Recent child welfare research has identified supervisors as key to retaining qualified and committed workers. This paper describes implementation of a federally funded child welfare training initiative designed to improve worker retention largely through developing, implementing, and evaluating a statewide supervisor training program in a

  19. Validating the Psychological Climate Scale in Voluntary Child Welfare

    ERIC Educational Resources Information Center

    Zeitlin, Wendy; Claiborne, Nancy; Lawrence, Catherine K.; Auerbach, Charles

    2016-01-01

    Objective: Organizational climate has emerged as an important factor in understanding and addressing the complexities of providing services in child welfare. This research examines the psychometric properties of each of the dimensions of Parker and colleagues' Psychological Climate Survey in a sample of voluntary child welfare workers. Methods:…

  20. Teaching Social Welfare Policy: A Comparison of Two Pedagogical Approaches

    ERIC Educational Resources Information Center

    Anderson, Debra K.; Harris, Barbara M.

    2005-01-01

    The use of experiential approaches to teach social welfare policy suggests that such methods may increase undergraduate social work students' knowledge of and skill in working on social and economic justice issues. This article compares 2 such methods using qualitative and quantitative approaches. The first teaches social welfare policy as a…

  1. Predicting Turnover: Validating the Intent to Leave Child Welfare Scale

    ERIC Educational Resources Information Center

    Auerbach, Charles; Schudrich, Wendy Zeitlin; Lawrence, Catherine K.; Claiborne, Nancy; McGowan, Brenda G.

    2014-01-01

    A number of proxies have been used in child welfare workforce research to represent actual turnover; however, there have been no psychometric studies to validate a scale specifically designed for this purpose. The Intent to Leave Child Welfare Scale is a proxy for actual turnover that measures workers' intention to leave. This scale was

  2. Validating the Psychological Climate Scale in Voluntary Child Welfare

    ERIC Educational Resources Information Center

    Zeitlin, Wendy; Claiborne, Nancy; Lawrence, Catherine K.; Auerbach, Charles

    2016-01-01

    Objective: Organizational climate has emerged as an important factor in understanding and addressing the complexities of providing services in child welfare. This research examines the psychometric properties of each of the dimensions of Parker and colleagues' Psychological Climate Survey in a sample of voluntary child welfare workers. Methods:

  3. Child Welfare Worker Characteristics and Job Satisfaction: A National Study

    ERIC Educational Resources Information Center

    Barth, Richard P.; Lloyd, E. Christopher; Christ, Sharon L.; Chapman, Mimi V.; Dickinson, Nancy S.

    2008-01-01

    The education, recruitment, training, and retention of a quality child welfare workforce is critical to the successful implementation of public policy and programs for the nation's most vulnerable children. Yet, national information about child welfare workers has never been collected. The National Survey of Child and Adolescent Well-Being is a

  4. Child Welfare Outcomes 2002-2005. Report to Congress

    ERIC Educational Resources Information Center

    US Department of Health and Human Services, 2008

    2008-01-01

    "Child Welfare Outcomes 2002-2005: Report to Congress" (Child Welfare Outcomes Report) is the seventh in a series of annual reports from the U.S. Department of Health and Human Services (the Department). The reports are developed in accordance with section 479A of the Social Security Act (as amended by the Adoption and Safe Families Act of 1997)

  5. Welfare Effects of Entry into International Markets with Licensing

    NASA Astrophysics Data System (ADS)

    Ferreira, F. A.; Ferreira, Fl.

    2008-10-01

    We study the effects of entry of a foreign firm on domestic welfare in the presence of licensing, when the entrant is technologically inferior to the incumbent. We show that foreign entry increases domestic welfare for intermediate (respectively, sufficiently large) technological differences between the firms under licensing with fixed fee (respectively, output royalty).

  6. Childcare Subsidies and the Transition from Welfare to Work

    ERIC Educational Resources Information Center

    Danziger, Sandra K.; Ananat, Elizabeth Oltmans; Browning, Kimberly G.

    2004-01-01

    We address how childcare subsidies help in the welfare-to-work transition relative to other factors. We examine how the policy operates, whether childcare problems differ by subsidy receipt, and the effect of subsidy on work. Data are from a random sample panel study of welfare recipients after 1996. Findings show that subsidy receipt reduces

  7. Families' Experience with Welfare Reform on Reservations in Arizona

    ERIC Educational Resources Information Center

    Pandey, Shanta; Zhan, Min; Collier-Tenison, Shannon

    2004-01-01

    This article documents the impact of the 1996 federal welfare legislation on American Indian families in the state of Arizona over a period of four years. The authors analyzed primary data obtained from interviews with 445 former or current welfare families with children from three Indian reservations: Navajo, San Carlos, and Salt River. Compared

  8. Charting the Impacts of University-Child Welfare Collaboration.

    ERIC Educational Resources Information Center

    Briar-Lawson, Katharine, Ed.; Zlotnik, Joan Levy, Ed.

    Few fields of service command as much public attention as child welfare. Workforce development is often a less visible yet critical response to service delivery crises and efforts to improve child and family outcomes. In the late 1980s, a campaign was undertaken to rebuild public child welfare systems with trained social workers. The subsequent

  9. Welfare Reform when Recipients Are Forward-Looking

    ERIC Educational Resources Information Center

    Swann, Christopher A.

    2005-01-01

    By studying recipients of aid under the Temporary Assistance for Needy Families (TANF) welfare scheme, the effect of time limits of welfare schemes on forward looking recipients is assessed using a discrete-choice dynamic programming framework model. The policy simulations for the preferred specification of utility reveal that two year time limits

  10. The How, Why and What of Child Welfare Services.

    ERIC Educational Resources Information Center

    Hepworth, H. Philip

    This paper reports findings of a retrospective longitudinal reconstruction of child welfare service activities in Canada. The first section discusses demographic developments and the child welfare services. It is reported that the increase in the number of children in care in the 20-year period from 1940 to 1960 was to some extent a reflection of

  11. The Role of European Welfare States in Explaining Resources Deprivation

    ERIC Educational Resources Information Center

    Muffels, Ruud; Fouarge, Didier

    2004-01-01

    In a previous paper in this journal (Headey et al., 2000) a comparison was made between three so-called 'best cases' of welfare regime types, the 'Liberal' US, 'the 'Corporatist' Germany and the 'Social-Democratic' Netherlands. The main conclusion was that the Social-Democratic welfare state performed best on nearly all social and economic…

  12. University Based Welfare to Work Project and Materials. Final Report.

    ERIC Educational Resources Information Center

    Kohler, Maxie P.

    Staff from the University of Alabama at Birmingham (UAB) and the Jefferson County, Alabama, Department of Human Resources (DHS) worked together to create a "pipeline to employment" at UAB for welfare recipients by combining on-the-job training with educational opportunities. Welfare recipients referred to UAB by the Jefferson County DHS were given

  13. Effective Teaching and Learning in Interprofessional Education in Child Welfare

    ERIC Educational Resources Information Center

    Whiteley, Robert F.; Gillespie, Judy; Robinson, Cathy; Watts, Wilda; Carter, Deb

    2014-01-01

    This article reports on research regarding interprofessional education (IPE) in child welfare conducted in 2009 and 2010. Pre service nursing, social worker and teacher education candidates participated in a workshop that "exposed" (Charles, Bainbridge & Gilbert, 2010) students to IPE in child welfare. This paper addresses a gap in…

  14. Demystifying Welfare: Its Feminization and Its Effect on Stakeholders

    ERIC Educational Resources Information Center

    Hartlep, Nicholas D.

    2008-01-01

    Welfare is misunderstood, mystified, and feminized by many stakeholders (i.e. government, media, majoritarian culture, etc.). This text analysis will assess how well the text achieved the following: (1) articulate why the current U.S. welfare state is based upon myths or false assumptions, (2) analyze what these false assumptions mean for

  15. Welfare Recipiency and Savings Outcomes in Individual Development Accounts

    ERIC Educational Resources Information Center

    Zhan, Min; Sherraden, Michael; Schreiner, Mark

    2004-01-01

    The authors examined how welfare recipiency is associated with savings outcomes in individual development accounts (IDAs), a structured savings program for low-income people. They investigated whether welfare recipients can save if they are provided with incentives. Data for this study ore from the American Dream Demonstration (ADD), the first

  16. Welfare Attitudes and Social Expenditure: Do Regimes Shape Public Opinion?

    ERIC Educational Resources Information Center

    Jakobsen, Tor Georg

    2011-01-01

    This article examines the link between regime types, social expenditure, and welfare attitudes. By employing data on 19 countries taken from the World Values Survey, the main aim is to see to what degree the institutions of a country affect the attitudes of its citizens. According to Esping-Andersen ("The three worlds of welfare capitalism".

  17. 42 CFR 86.19 - Human subjects; animal welfare.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Occupational Safety and Health Training Grants § 86.19 Human subjects; animal welfare. No grant award may be made under this subpart unless the applicant has complied with: (a) 45 CFR part 46 pertaining to the... 42 Public Health 1 2010-10-01 2010-10-01 false Human subjects; animal welfare. 86.19 Section...

  18. 42 CFR 86.19 - Human subjects; animal welfare.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Occupational Safety and Health Training Grants § 86.19 Human subjects; animal welfare. No grant award may be made under this subpart unless the applicant has complied with: (a) 45 CFR part 46 pertaining to the... 42 Public Health 1 2012-10-01 2012-10-01 false Human subjects; animal welfare. 86.19 Section...

  19. 42 CFR 86.19 - Human subjects; animal welfare.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Occupational Safety and Health Training Grants § 86.19 Human subjects; animal welfare. No grant award may be made under this subpart unless the applicant has complied with: (a) 45 CFR part 46 pertaining to the... 42 Public Health 1 2013-10-01 2013-10-01 false Human subjects; animal welfare. 86.19 Section...

  20. 42 CFR 86.19 - Human subjects; animal welfare.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Occupational Safety and Health Training Grants § 86.19 Human subjects; animal welfare. No grant award may be made under this subpart unless the applicant has complied with: (a) 45 CFR part 46 pertaining to the... 42 Public Health 1 2011-10-01 2011-10-01 false Human subjects; animal welfare. 86.19 Section...

  1. 42 CFR 86.19 - Human subjects; animal welfare.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Occupational Safety and Health Training Grants § 86.19 Human subjects; animal welfare. No grant award may be made under this subpart unless the applicant has complied with: (a) 45 CFR part 46 pertaining to the... 42 Public Health 1 2014-10-01 2014-10-01 false Human subjects; animal welfare. 86.19 Section...

  2. Measuring Is Believing! Improving Conventional Indicators of Welfare State Development

    ERIC Educational Resources Information Center

    Olaskoaga-Larrauri, Jon; Alaez-Aller, Ricardo; Diaz-de-Basurto, Pablo

    2010-01-01

    Welfare effort (social spending as a percentage of GDP) has conventionally been the preferred measure for comparisons in space and time of the level of development of welfare states. However, a wide variety of other measuring systems are potentially available in this field, because there are different sources and different methods for calculating…

  3. Improving Collaboration between Welfare and Workforce Development Agencies.

    ERIC Educational Resources Information Center

    Relave, Nanette

    2002-01-01

    Collaboration between welfare and workforce development agencies has increased since the implementation of welfare reform. Federal legislation, state and local policy-making environments, and the capacity of potential partners to serve an agency's clients affect agency collaboration. The following broad approaches to collaboration have been

  4. Welfare Reform in California: Early Results from the Impact Analysis.

    ERIC Educational Resources Information Center

    Klerman, Jacob Alex; Hotz, V. Joseph; Reardon, Elaine; Cox, Amy G.; Farley, Donna O.; Haider, Steven J.; Imbens, Guido; Schoeni, Robert

    The impact of California Work Opportunity and Responsibility to Kids (CalWORKS), which was passed to increase California welfare recipients' participation in welfare-to-work (WTW) activities, was examined. The impact study consisted of a nonexperimental program evaluation that used statistical models to estimate causal effects and a simulation

  5. Welfare Attitudes and Social Expenditure: Do Regimes Shape Public Opinion?

    ERIC Educational Resources Information Center

    Jakobsen, Tor Georg

    2011-01-01

    This article examines the link between regime types, social expenditure, and welfare attitudes. By employing data on 19 countries taken from the World Values Survey, the main aim is to see to what degree the institutions of a country affect the attitudes of its citizens. According to Esping-Andersen ("The three worlds of welfare capitalism".…

  6. Predicting Turnover: Validating the Intent to Leave Child Welfare Scale

    ERIC Educational Resources Information Center

    Auerbach, Charles; Schudrich, Wendy Zeitlin; Lawrence, Catherine K.; Claiborne, Nancy; McGowan, Brenda G.

    2014-01-01

    A number of proxies have been used in child welfare workforce research to represent actual turnover; however, there have been no psychometric studies to validate a scale specifically designed for this purpose. The Intent to Leave Child Welfare Scale is a proxy for actual turnover that measures workers' intention to leave. This scale was…

  7. Community College Participation in Welfare Programs: Do State Policies Matter?

    ERIC Educational Resources Information Center

    Melendez, Edwin; Falcon, Luis; Bivens, Josh

    2003-01-01

    Reports that 80% of community colleges have implemented programs targeting welfare recipients. Examines policies affecting community college participation in welfare-to-work programs, and how, why, and to what extent community colleges are responding to these initiatives. Identifies qualities of some of the most successful programs. Includes five

  8. 12 CFR 24.3 - Public welfare investments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Public welfare investments. 24.3 Section 24.3... DEVELOPMENT ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE INVESTMENTS § 24.3 Public... investment would receive consideration under 12 CFR 25.23 as a “qualified investment.”...

  9. Accessibility and Clarity of State Child Welfare Agency Mission Statements

    ERIC Educational Resources Information Center

    Busch, Monique; Folaron, Gail

    2005-01-01

    The authors reviewed 40 mission statements guiding U.S. public child welfare practice for accessibility, clarity, and values. Nine of the 40 state-administered child welfare agencies had not posted their missions on the Web as of October 2002, and 30 mission statements required a 12th-grade or college reading level for easy comprehension. The…

  10. 12 CFR 24.3 - Public welfare investments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Public welfare investments. 24.3 Section 24.3... DEVELOPMENT ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE INVESTMENTS § 24.3 Public... investment would receive consideration under 12 CFR 25.23 as a “qualified investment.”...

  11. 12 CFR 24.3 - Public welfare investments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Public welfare investments. 24.3 Section 24.3... DEVELOPMENT ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE INVESTMENTS § 24.3 Public... investment would receive consideration under 12 CFR 25.23 as a “qualified investment.”...

  12. 12 CFR 24.3 - Public welfare investments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Public welfare investments. 24.3 Section 24.3... DEVELOPMENT ENTITIES, COMMUNITY DEVELOPMENT PROJECTS, AND OTHER PUBLIC WELFARE INVESTMENTS § 24.3 Public... investment would receive consideration under 12 CFR 25.23 as a “qualified investment.”...

  13. Did Welfare Reform Influence the Fertility of Young Teens?

    ERIC Educational Resources Information Center

    Lopoo, Leonard M.; DeLeire, Thomas

    2006-01-01

    During the 1990s, states made several reforms to their welfare programs designed to reduce teenage fertility among minors. Among the most prominent of these changes, states started requiring teenage mothers younger than 18 to live with a parent or legal guardian and enroll in high school in order to receive welfare benefits. Using natality data

  14. A Stock-Flow Analysis of the Welfare Caseload

    ERIC Educational Resources Information Center

    Klerman, Jacob Alex; Haider, Steven J.

    2004-01-01

    A reconsideration of the methods used to access the welfare caseload movements during the 1990s is done. A model is developed in which the welfare caseload is the net outcome of past flows onto and off of the caseloads and it is shown that such a stock-flow model could explain some of the anomalous findings of the earlier studies.

  15. 29 CFR 2510.3-1 - Employee welfare benefit plan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Employee welfare benefit plan. 2510.3-1 Section 2510.3-1... TERMS USED IN SUBCHAPTERS C, D, E, F, AND G OF THIS CHAPTER 2510.3-1 Employee welfare benefit plan. (a) General. (1) The purpose of this section is to clarify the definition of the terms employee...

  16. The Role of European Welfare States in Explaining Resources Deprivation

    ERIC Educational Resources Information Center

    Muffels, Ruud; Fouarge, Didier

    2004-01-01

    In a previous paper in this journal (Headey et al., 2000) a comparison was made between three so-called 'best cases' of welfare regime types, the 'Liberal' US, 'the 'Corporatist' Germany and the 'Social-Democratic' Netherlands. The main conclusion was that the Social-Democratic welfare state performed best on nearly all social and economic

  17. 29 CFR 2510.3-1 - Employee welfare benefit plan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Employee welfare benefit plan. 2510.3-1 Section 2510.3-1... TERMS USED IN SUBCHAPTERS C, D, E, F, AND G OF THIS CHAPTER 2510.3-1 Employee welfare benefit plan. (a) General. (1) The purpose of this section is to clarify the definition of the terms employee...

  18. Welfare Regimes and Educational Inequality: A Cross-National Exploration

    ERIC Educational Resources Information Center

    Peter, Tracey; Edgerton, Jason D.; Roberts, Lance W.

    2010-01-01

    Research on welfare state regimes and research on educational policy share a common concern for the reduction of social inequality. On one hand, welfare state research is typically designed within a comparative approach where scholars investigate similarities and differences in social institutions across selected countries. On the other hand, the

  19. Measuring Is Believing! Improving Conventional Indicators of Welfare State Development

    ERIC Educational Resources Information Center

    Olaskoaga-Larrauri, Jon; Alaez-Aller, Ricardo; Diaz-de-Basurto, Pablo

    2010-01-01

    Welfare effort (social spending as a percentage of GDP) has conventionally been the preferred measure for comparisons in space and time of the level of development of welfare states. However, a wide variety of other measuring systems are potentially available in this field, because there are different sources and different methods for calculating

  20. 29 CFR 2510.3-1 - Employee welfare benefit plan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Employee welfare benefit plan. 2510.3-1 Section 2510.3-1... TERMS USED IN SUBCHAPTERS C, D, E, F, AND G OF THIS CHAPTER 2510.3-1 Employee welfare benefit plan. (a) General. (1) The purpose of this section is to clarify the definition of the terms employee...

  1. Welfare Time Limits: State Policies, Implementation, and Effects on Families.

    ERIC Educational Resources Information Center

    Bloom, Dan; Farrell, Mary; Fink, Barbara

    The effect of welfare time limits on families in different states was examined in a comprehensive study that involved the following activities: (1) a survey of state welfare administrators regarding states' time-limit policies and experiences to date; (2) site visits to five states; and (3) a synthesis of research on time limits. The following

  2. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... institution has complied with: (a) 45 CFR part 46 pertaining to the protection of human subjects; and (b... 42 Public Health 1 2012-10-01 2012-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where...

  3. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... institution has complied with: (a) 45 CFR part 46 pertaining to the protection of human subjects; and (b... 42 Public Health 1 2010-10-01 2010-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where...

  4. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... institution has complied with: (a) 45 CFR part 46 pertaining to the protection of human subjects; and (b... 42 Public Health 1 2014-10-01 2014-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where...

  5. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... institution has complied with: (a) 45 CFR part 46 pertaining to the protection of human subjects; and (b... 42 Public Health 1 2013-10-01 2013-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where...

  6. 42 CFR 86.33 - Human subjects; animal welfare.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... institution has complied with: (a) 45 CFR part 46 pertaining to the protection of human subjects; and (b... 42 Public Health 1 2011-10-01 2011-10-01 false Human subjects; animal welfare. 86.33 Section 86.33... Occupational Safety and Health Direct Traineeships § 86.33 Human subjects; animal welfare. Where...

  7. Correlates of welfare dependency among immigrants in Australia.

    PubMed

    Khoo, S

    1994-01-01

    "This article investigates some of the factors that are associated with welfare dependency among immigrants in Australia. It examines the role of factors such as gender, age, migration category, birthplace, period of arrival and educational background in explaining immigrants' dependence on government pensions and benefits as their main source of income." The author finds that there are "significant differences in welfare dependency...by birthplace and migration category even after controlling for age, education and employment status. Immigrants from Vietnam, Lebanon and Turkey were more likely than others to be dependent on welfare. Refugees were also more likely than other immigrants to be dependent on welfare; however the effect of refugee status on welfare dependency diminished with duration of residence in Australia." PMID:12287279

  8. Status of animal welfare awareness of producers and direction of animal welfare research in the future.

    PubMed

    Albright, J L

    1983-10-01

    Most producers are as humane in their thinking and care of animals as are those people involved in the many activist organizations springing up around the United States. That there are no major problems of animal welfare with the dairy cow posed by changes of systems has been suggested. However, veal producers have been criticized for their production practices. The major areas to be resolved between animal welfare advocates and commercial veal producers is the matter of individual pens versus group systems that permit general freedom of movement. Recent developments of dairy cattle management that have improved the comfort and well-being of dairy cattle include raising of calves in individual pens or hutches; exercise prior to calving; change of flooring (grooving of concrete, use of dirt exercise lots, elimination of slats); use of free stalls rather than loose housing; use of materials to keep cows dry, clean, out of the mud, cool, and free from flies and pests; and elimination of stray voltage. Design of a system for animal welfare is only part of the solution. The most important factor in determining stress in the herd is the behavior, attitude, and consistency of the caretaker. PMID:6358291

  9. Knowledge of the Animal Welfare Act and Animal Welfare Regulations Influences Attitudes toward Animal Research

    PubMed Central

    2015-01-01

    Recent public-opinion polls indicate that Americans have shown a decline in support for animal experimentation, and several reports suggest a relationship between people's knowledge of animal welfare regulations and their attitudes toward animal research. Therefore, this study was designed to assess respondent's knowledge of several provisions in the Animal Welfare Act (AWA) and Animal Welfare Regulations (AWR), and determine whether exposure to elements of this legislation would influence an individual's attitudes toward the use of animals in research. A survey was used to assess knowledge of animal research regulations and attitudes toward animal research from a sample of individuals recruited through Amazon's Mechanical Turk crowdsourcing marketplace. Results from study 1 confirmed the hypothesis that respondents had little knowledge of various federal regulations that govern animal research activities. Data from study 2 revealed that exposure to elements of the AWA and AWR influenced participants’ attitudes toward the use of animals in research. These results suggest that providing information to the general public about the AWA and AWR that protect laboratory animals from abuse and neglect may help alleviate concerns about using animals in research settings. PMID:25651094

  10. Chromosome Aberrations in Astronauts

    NASA Technical Reports Server (NTRS)

    George, Kerry A.; Durante, M.; Cucinotta, Francis A.

    2007-01-01

    A review of currently available data on in vivo induced chromosome damage in the blood lymphocytes of astronauts proves that, after protracted exposure of a few months or more to space radiation, cytogenetic biodosimetry analyses of blood collected within a week or two of return from space provides a reliable estimate of equivalent radiation dose and risk. Recent studies indicate that biodosimetry estimates from single spaceflights lie within the range expected from physical dosimetry and biophysical models, but very large uncertainties are associated with single individual measurements and the total sample population remains low. Retrospective doses may be more difficult to estimate because of the fairly rapid time-dependent loss of "stable" aberrations in blood lymphocytes. Also, biodosimetry estimates from individuals who participate in multiple missions, or very long (interplanetary) missions, may be complicated by an adaptive response to space radiation and/or changes in lymphocyte survival and repopulation. A discussion of published data is presented and specific issues related to space radiation biodosimetry protocols are discussed.

  11. DNA Repair and Chromosomal Translocations.

    PubMed

    Bohlander, Stefan K; Kakadia, Purvi M

    2015-01-01

    The balance between DNA damage, especially double strand breaks, and DNA damage repair is a critical determinant of chromosomal translocation frequency. The non-homologous end-joining repair (NHEJ) pathways seem to play the major role in the generation of chromosomal translocations. The "landscape" of chromosomal translocation identified in malignancies is largely due to selection processes which operate on the growth advantages conveyed to the cells by the functional consequences of chromosomal translocations (i.e., oncogenic fusion proteins and overexpression of oncogenes, both compromising tumor suppressor gene functions). Newer studies have shown that there is an abundance of local rearrangements in many tumors, like small deletions and inversions. A better understanding of the interplay between DNA repair mechanisms and the generation of tumorigenic translocations will, among many other things, depend on an improved understanding of DNA repair mechanisms and their interplay with chromatin and the 3D organization of the interphase nucleus. PMID:26376870

  12. Wellhead equipment support

    SciTech Connect

    Nichols, R.P.

    1987-03-24

    A wellhead assembly is described for supporting equipment in a well, comprising: a suspension nut having a threaded outer surface; a wellhead member having an inner threaded surface adapted to mesh with the threaded outer surface of the suspension nut; the suspension nut having a projection extending axially from its threaded outer surface and having an inner surface adapted to support equipment in the well; at least a portion of the inner surface for supporting the equipment facing both inwardly and upwardly such that force exerted by the weight of the equipment against the inner surface is transformed at least in part to a radially outwardly directed force; the projecting having an outer surface sized such that the outer surface is spaced from an inner surface of the wellhead member in the absence of force exerted against the inner surface of the projection such that the projection is deflected outwardly by the force exerted by the weight of the equipment against the inner surface.

  13. The Reality of Welfare-to-Work: Employment Opportunities for Women Affected by Welfare Time Limits in Texas.

    ERIC Educational Resources Information Center

    Lawson, Leslie O.; King, Christopher T.

    Researchers assembled a database of current and projected information on the following: welfare recipients; other female participants in the labor market; employment, occupational availability, and job openings; and occupational characteristics. The database was used in a multistep process to project the number of women forced to leave welfare

  14. Child Welfare: Most States Are Developing Statewide Information Systems, but Reliability of Child Welfare Data Could Be Improved.

    ERIC Educational Resources Information Center

    Pietrowiak, Diana; Schibanoff, Sara L.

    To better monitor children and families served by state child welfare agencies, Congress authorized matching funds for the development of statewide automatic child welfare information systems (SACWIS) and required that U.S. Department of Health and Human Services (HHS) compile information on children served by state agencies. This report to

  15. Methods for chromosome-specific staining

    DOEpatents

    Gray, Joe W. (Livermore, CA); Pinkel, Daniel (Walnut Creek, CA)

    1995-01-01

    Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.

  16. Computational model for chromosomal instabilty

    NASA Astrophysics Data System (ADS)

    Zapperi, Stefano; Bertalan, Zsolt; Budrikis, Zoe; La Porta, Caterina

    2015-03-01

    Faithful segregation of genetic material during cell division requires alignment of the chromosomes between the spindle poles and attachment of their kinetochores to each of the poles. Failure of these complex dynamical processes leads to chromosomal instability (CIN), a characteristic feature of several diseases including cancer. While a multitude of biological factors regulating chromosome congression and bi-orientation have been identified, it is still unclear how they are integrated into a coherent picture. Here we address this issue by a three dimensional computational model of motor-driven chromosome congression and bi-orientation. Our model reveals that successful cell division requires control of the total number of microtubules: if this number is too small bi-orientation fails, while if it is too large not all the chromosomes are able to congress. The optimal number of microtubules predicted by our model compares well with early observations in mammalian cell spindles. Our results shed new light on the origin of several pathological conditions related to chromosomal instability.

  17. Microelasticity of Single Mitotic Chromosomes

    NASA Astrophysics Data System (ADS)

    Poirier, Michael; Eroglu, Sertac; Chatenay, Didier; Marko, John F.; Hirano, Tatsuya

    2000-03-01

    The force-extension behavior of mitotic chromosomes from the newt TVI tumor cell line was studied using micropipette manipulation and force measuring techniques. Reversible, linear elastic response was observed for extensions up to 5 times the native length; the force required to double chromosome length was 1 nanonewton (nN). For further elongations, the linear response teminates at a force plateau of 15 nN and at an extension of 20x. Beyond this extension, the chromosome breaks at elongations between 20x and 70x. These results will be compared to the similar behavior of mitotic chromosomes from explanted newt cells (Poirier, Eroglu, Chatenay and Marko, Mol. Biol. Cell, in press). Also, the effect of biochemical modifications on the elasticity was studied. Ethidium Bromide, which binds to DNA, induces up to a 10 times increase in the Young's modulus. Anti-XCAP-E, which binds to a putative chromosome folding protein, induces up to a 2 times increase in the Young's modulus. Preliminary results on the dynamical relaxation of chromosomes will also be presented. Support of this research through a Biomedical Engineering Research Grant from The Whitaker Foundation is gratefully acknowledged.

  18. Chromosome Architecture and Genome Organization

    PubMed Central

    Bernardi, Giorgio

    2015-01-01

    How the same DNA sequences can function in the three-dimensional architecture of interphase nucleus, fold in the very compact structure of metaphase chromosomes and go precisely back to the original interphase architecture in the following cell cycle remains an unresolved question to this day. The strategy used to address this issue was to analyze the correlations between chromosome architecture and the compositional patterns of DNA sequences spanning a size range from a few hundreds to a few thousands Kilobases. This is a critical range that encompasses isochores, interphase chromatin domains and boundaries, and chromosomal bands. The solution rests on the following key points: 1) the transition from the looped domains and sub-domains of interphase chromatin to the 30-nm fiber loops of early prophase chromosomes goes through the unfolding into an extended chromatin structure (probably a 10-nm “beads-on-a-string” structure); 2) the architectural proteins of interphase chromatin, such as CTCF and cohesin sub-units, are retained in mitosis and are part of the discontinuous protein scaffold of mitotic chromosomes; 3) the conservation of the link between architectural proteins and their binding sites on DNA through the cell cycle explains the “mitotic memory” of interphase architecture and the reversibility of the interphase to mitosis process. The results presented here also lead to a general conclusion which concerns the existence of correlations between the isochore organization of the genome and the architecture of chromosomes from interphase to metaphase. PMID:26619076

  19. 20 CFR 645.110 - What are the purposes of the Welfare-to-Work Program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... hard-to-employ welfare recipients and certain noncustodial parents into transitional employment... retention services which will assist the hard-to-employ welfare recipient and certain noncustodial parents... with large numbers of hard-to-employ welfare recipients....

  20. 20 CFR 645.110 - What are the purposes of the Welfare-to-Work Program?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... hard-to-employ welfare recipients and certain noncustodial parents into transitional employment... retention services which will assist the hard-to-employ welfare recipient and certain noncustodial parents... with large numbers of hard-to-employ welfare recipients....

  1. 20 CFR 645.110 - What are the purposes of the Welfare-to-Work Program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... hard-to-employ welfare recipients and certain noncustodial parents into transitional employment... retention services which will assist the hard-to-employ welfare recipient and certain noncustodial parents... with large numbers of hard-to-employ welfare recipients....

  2. 20 CFR 645.110 - What are the purposes of the Welfare-to-Work Program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... hard-to-employ welfare recipients and certain noncustodial parents into transitional employment... retention services which will assist the hard-to-employ welfare recipient and certain noncustodial parents... with large numbers of hard-to-employ welfare recipients....

  3. Numerically abnormal chromosome constitutions in humans

    SciTech Connect

    1993-12-31

    Chapter 24, discusses numerically abnormal chromosome constitutions in humans. This involves abnormalities of human chromosome number, including polyploidy (when the number of sets of chromosomes increases) and aneuploidy (when the number of individual normal chromosomes changes). Chapter sections discuss the following chromosomal abnormalities: human triploids, imprinting and uniparental disomy, human tetraploids, hydatidiform moles, anomalies caused by chromosomal imbalance, 13 trisomy (D{sub 1} trisomy, Patau syndrome), 21 trisomy (Down syndrome), 18 trisomy syndrome (Edwards syndrome), other autosomal aneuploidy syndromes, and spontaneous abortions. The chapter concludes with remarks on the nonrandom participation of chromosomes in trisomy. 69 refs., 3 figs., 4 tabs.

  4. German mining equipment

    SciTech Connect

    Not Available

    1993-10-01

    The German mining equipment industry developed to supply machines and services to the local mining industry, i.e., coal, lignite, salt, potash, ore mining, industrial minerals, and quarrying. The sophistication and reliability of its technology also won it worldwide export markets -- which is just as well since former major domestic mining sectors such as coal and potash have declined precipitously, and others such as ore mining have all but disappeared. Today, German mining equipment suppliers focus strongly on export sales, and formerly unique German mining technologies such as continuous mining with bucket wheel excavators and conveyors for open pits, or plowing of underground coal longwalls are widely used abroad. The status of the German mining equipment industry is reviewed.

  5. [Medical Equipment Maintenance Methods].

    PubMed

    Liu, Hongbin

    2015-09-01

    Due to the high technology and the complexity of medical equipment, as well as to the safety and effectiveness, it determines the high requirements of the medical equipment maintenance work. This paper introduces some basic methods of medical instrument maintenance, including fault tree analysis, node method and exclusive method which are the three important methods in the medical equipment maintenance, through using these three methods for the instruments that have circuit drawings, hardware breakdown maintenance can be done easily. And this paper introduces the processing methods of some special fault conditions, in order to reduce little detours in meeting the same problems. Learning is very important for stuff just engaged in this area. PMID:26904890

  6. Equipment Operational Requirements

    SciTech Connect

    Greenwalt, B; Henderer, B; Hibbard, W; Mercer, M

    2009-06-11

    The Iraq Department of Border Enforcement is rich in personnel, but poor in equipment. An effective border control system must include detection, discrimination, decision, tracking and interdiction, capture, identification, and disposition. An equipment solution that addresses only a part of this will not succeed, likewise equipment by itself is not the answer without considering the personnel and how they would employ the equipment. The solution should take advantage of the existing in-place system and address all of the critical functions. The solutions are envisioned as being implemented in a phased manner, where Solution 1 is followed by Solution 2 and eventually by Solution 3. This allows adequate time for training and gaining operational experience for successively more complex equipment. Detailed descriptions of the components follow the solution descriptions. Solution 1 - This solution is based on changes to CONOPs, and does not have a technology component. It consists of observers at the forts and annexes, forward patrols along the swamp edge, in depth patrols approximately 10 kilometers inland from the swamp, and checkpoints on major roads. Solution 2 - This solution adds a ground sensor array to the Solution 1 system. Solution 3 - This solution is based around installing a radar/video camera system on each fort. It employs the CONOPS from Solution 1, but uses minimal ground sensors deployed only in areas with poor radar/video camera coverage (such as canals and streams shielded by vegetation), or by roads covered by radar but outside the range of the radar associated cameras. This document provides broad operational requirements for major equipment components along with sufficient operational details to allow the technical community to identify potential hardware candidates. Continuing analysis will develop quantities required and more detailed tactics, techniques, and procedures.

  7. Flow karyotyping and sorting of human chromosomes

    SciTech Connect

    Gray, J.W.; Lucas, J.; Peters, D.; Pinkel, D.; Trask, B.; van den Engh, G.; Van Dilla, M.A.

    1986-07-16

    Flow cytometry and sorting are becoming increasingly useful as tools for chromosome classfication and for the detection of numerical and structural chromosome aberrations. Chromosomes of a single type can be purified with these tools to facilitate gene mapping or production of chromosome specific recombinant DNA libraries. For analysis of chromosomes with flow cytometry, the chromosomes are extracted from mitotic cells, stained with one or more fluorescent dyes and classified one-by-one according to their dye content(s). Thus, the flow approach is fundamentally different than conventional karyotyping where chromosomes are classified within the context of a metaphase spread. Flow sorting allows purification of chromosomes that can be distinguished flow cytometrically. The authors describe the basic principles of flow cytometric chromosome classification i.e. flow karyotyping, and chromosome sorting and describe several applications. 30 refs., 8 figs.

  8. Equipment Management Manual

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The NASA Equipment Management Manual (NHB 4200.1) is issued pursuant to Section 203(c)(1) of the National Aeronautics and Space Act of 1958, as amended (42 USC 2473), and sets forth policy, uniform performance standards, and procedural guidance to NASA personnel for the acquisition, management, and use of NASA-owned equipment. This revision is effective upon receipt. This is a controlled manual, issued in loose-leaf form, and revised through page changes. Additional copies for internal use may be obtained through normal distribution.

  9. Human chromosomes: Structure, behavior, and effects

    SciTech Connect

    Therman, E.; Susman, M.

    1993-12-31

    The book `Human Chromosomes: Structure, Behavior, and Effects` covers the most important topics regarding human chromosomes and current research in cytogenetics. Attention is given both to structure and function of autosomes and sex chromosomes, as well as definitions and causes of chromosomal aberrations. This often involves discussion about various aspects of the cell cycle (both mitosis and meiosis). Methods and techniques involved in researching and mapping human chromosomes are also discussed.

  10. Amplification of chromosomal DNA in situ

    DOEpatents

    Christian, Allen T.; Coleman, Matthew A.; Tucker, James D.

    2002-01-01

    Amplification of chromosomal DNA in situ to increase the amount of DNA associated with a chromosome or chromosome region is described. The amplification of chromosomal DNA in situ provides for the synthesis of Fluorescence in situ Hybridization (FISH) painting probes from single dissected chromosome fragments, the production of cDNA libraries from low copy mRNAs and improved in Comparative Genomic Hybridization (CGH) procedures.

  11. Defining, assessing and promoting the welfare of farmed fish.

    PubMed

    Huntingford, F A; Kadri, S

    2014-04-01

    As currently practised, the culture of fish for food potentially raises concerns about the welfare of farmed fish, and this is a topic that has received considerable attention. As vertebrates, fish share a number of features with the birds and mammals that are more commonly farmed, so many welfare principles derived from consideration of these groups may also be applied to fish. However, fish have a long, separate evolutionary history and are also adapted to a very different, aquatic environment. For these reasons, they have a number of special features that are relevant to how welfare is defined, assessed and promoted and these are discussed. The various methods that are available to researchers for identifying and assessing good and bad welfare in fish are considered, including assessment of physical health and physiological, behavioural and genomic status. The subset of practical welfare indicators that can be used on working farms is also reviewed. Various aspects of intensive aquaculture that can potentially compromise fish welfare are outlined, as are some strategies available for mitigating such adverse effects. Finally, the paper ends by looking briefly to the future, identifying likely changes in aquaculture practices and how these might affect the welfare of farmed fish. PMID:25000796

  12. Chromosome I Controls Chromosome II Replication in Vibrio cholerae

    PubMed Central

    Baek, Jong Hwan; Chattoraj, Dhruba K.

    2014-01-01

    Control of chromosome replication involves a common set of regulators in eukaryotes, whereas bacteria with divided genomes use chromosome-specific regulators. How bacterial chromosomes might communicate for replication is not known. In Vibrio cholerae, which has two chromosomes (chrI and chrII), replication initiation is controlled by DnaA in chrI and by RctB in chrII. DnaA has binding sites at the chrI origin of replication as well as outside the origin. RctB likewise binds at the chrII origin and, as shown here, to external sites. The binding to the external sites in chrII inhibits chrII replication. A new kind of site was found in chrI that enhances chrII replication. Consistent with its enhancing activity, the chrI site increased RctB binding to those chrII origin sites that stimulate replication and decreased binding to other sites that inhibit replication. The differential effect on binding suggests that the new site remodels RctB. The chaperone-like activity of the site is supported by the finding that it could relieve the dependence of chrII replication on chaperone proteins DnaJ and DnaK. The presence of a site in chrI that specifically controls chrII replication suggests a mechanism for communication between the two chromosomes for replication. PMID:24586205

  13. Clinical performance of a system for semiautomated chromosome analysis.

    PubMed

    Lundsteen, C; Gerdes, T; Maahr, J; Philip, J

    1987-09-01

    Until recently equipment for automated chromosome analysis has not been used for routine purposes in clinical cytogenetic laboratories. During a 3 1/2-year period the chromosome laboratory of Rigshospitalet has tested the Magiscan chromosome system under routine conditions and performed the first evaluation of its clinical performance. The system consists of an image processor with a light pen for manual interaction connected to a hard-copy printer and a microscope with a TV camera and a motorized scanning stage for eight slides. Automated metaphase finding takes place without operator assistance. An operator is involved in the analysis after the metaphases are located. Using two of these complete systems, we have performed a total of 4,691 chromosome analyses comprising a count of 10 metaphases, of which three were "eyeball" karyotyped and one was "machine" karyotyped. Presently, two-thirds of our prenatal analyses (amniotic-cell cultures) are carried out with these two machines. A third Magiscan system without scanning stage is used as a "karyotyping-only" system to produce hard-copy karyograms in those cases in which metaphases are manually located and counted in the microscope. Since the end of 1984, 4,773 additional machine karyograms have been produced with this system. With a complete system, a prenatal analysis can be carried out in an average of 35 min. The average time for a machine karyotype is 7 min. Since 1984 the productivity of the laboratory has increased 17%-20% without enlarging the staff. PMID:3631082

  14. Lennox - Student Training Equipment.

    ERIC Educational Resources Information Center

    Lennox Industries, Inc., Marshalltown, IA.

    Presents a series of demonstration units designed by Lennox Industries for the purpose of training students to become familiar with Lennox mechanical equipment. Demonstrators are designed to present technical information in a clear simplified manner thus reducing frustration for the beginning trainee. The following demonstrators are available--(1)

  15. STDN ranging equipment

    NASA Technical Reports Server (NTRS)

    Jones, C. E.

    1975-01-01

    Final results of the Spaceflight Tracking and Data Network (STDN) Ranging Equipment program are summarized. Basic design concepts and final design approaches are described. Theoretical analyses which define requirements and support the design approaches are presented. Design verification criteria are delineated and verification test results are specified.

  16. Lennox - Student Training Equipment.

    ERIC Educational Resources Information Center

    Lennox Industries, Inc., Marshalltown, IA.

    Presents a series of demonstration units designed by Lennox Industries for the purpose of training students to become familiar with Lennox mechanical equipment. Demonstrators are designed to present technical information in a clear simplified manner thus reducing frustration for the beginning trainee. The following demonstrators are available--(1)…

  17. Equipment & New Products.

    ERIC Educational Resources Information Center

    Poitras, Adrian W., Ed.

    1977-01-01

    Identifies several pieces of equipment and new products for use in college science teaching such as: (1)rotary retracting microtome; (2)airflow bench; and (3)digital stop clock. A description of each one, the price, and the address of the seller are also presented. (HM)

  18. Engineer Equipment Operator.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    This student guide, one of a series of correspondence training courses designed to improve the job performance of members of the Marine Corps, deals with the skills needed by engineer equipment operators. Addressed in the seven individual units of the course are the following topics: introduction to Military Occupation Specialty (MOS) 1345…

  19. Engineer Equipment Chief.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    This student guide, one of a series of correspondence training courses designed to improve the job performance of members of the Marine Corps, deals with the skills needed by engineer equipment chiefs. Addressed in the five individual units of the course are the following topics: construction management (planning, scheduling, and supervision);…

  20. Equipment & New Products.

    ERIC Educational Resources Information Center

    Poitras, Adrian W., Ed.

    1977-01-01

    Presents information about equipment and new products such as the melting point instrument and TV-microscope coupler which are helpful in college science teaching. Descriptions of each product, how it operates, its prices, and address for ordering are presented. (HM)

  1. Dairy Equipment Lubrication

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Lake To Lake Dairy Cooperative, Manitowoc, Wisconsin, operates four plants in Wisconsin for processing milk, butter and cheese products from its 1,300 member farms. The large co-op was able to realize substantial savings by using NASA information for improved efficiency in plant maintenance. Under contract to Marshall Space Flight Center, Midwest Research Institute compiled a handbook consolidating information about commercially available lubricants. The handbook details chemical and physical properties, applications, specifications, test procedures and test data for liquid and solid lubricants. Lake To Lake's plant engineer used the handbook to effect savings in maintenance labor and materials costs by reducing the number of lubricants used on certain equipment. Strict U.S. Department of Agriculture and Food and Drug Administration regulations preclude lubrication changes n production equipment, but the co-op's maintenance chief was able to eliminate seven types of lubricants for ancillary equipment, such as compressors and high pressure pumps. Handbook data enabled him to select comparable but les expensive lubricants in the materials consolidation process, and simplified lubrication schedules and procedures. The handbook is in continuing use as a reference source when a new item of equipment is purchased.

  2. The EQUIP Program

    ERIC Educational Resources Information Center

    Gibbs, John C.; Potter, Granville Bud; DiBiase, Ann-Marie; Devlin, Renee

    2008-01-01

    Youth who present anti-social behavior need powerful interventions that strengthen empathy, counter negative peer influence, and challenge thinking errors. This article recaps some key points about EQUIP, a Positive Peer Culture (PPC)-based cognitive behavioral intervention program for behaviorally at-risk youth, and notes how the program has

  3. Basic Engineer Equipment Mechanic.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    This student guide, one of a series of correspondence training courses designed to improve the job performance of members of the Marine Corps, deals with the skills needed by basic engineer equipment mechanics. Addressed in the four individual units of the course are the following topics: mechanics and their tools (mechanics, hand tools, and power…

  4. The EQUIP Program

    ERIC Educational Resources Information Center

    Gibbs, John C.; Potter, Granville Bud; DiBiase, Ann-Marie; Devlin, Renee

    2008-01-01

    Youth who present anti-social behavior need powerful interventions that strengthen empathy, counter negative peer influence, and challenge thinking errors. This article recaps some key points about EQUIP, a Positive Peer Culture (PPC)-based cognitive behavioral intervention program for behaviorally at-risk youth, and notes how the program has…

  5. Chromosome therapy. Correction of large chromosomal aberrations by inducing ring chromosomes in induced pluripotent stem cells (iPSCs).

    PubMed

    Kim, Taehyun; Bershteyn, Marina; Wynshaw-Boris, Anthony

    2014-01-01

    The fusion of the short (p) and long (q) arms of a chromosome is referred to as a "ring chromosome." Ring chromosome disorders occur in approximately 1 in 50,000-100,000 patients. Ring chromosomes can result in birth defects, mental disabilities, and growth retardation if additional genes are deleted during the formation of the ring. Due to the severity of these large-scale aberrations affecting multiple contiguous genes, no possible therapeutic strategies for ring chromosome disorders have so far been proposed. Our recent study (Bershteyn et al.) using patient-derived fibroblast lines containing ring chromosomes, found that cellular reprogramming of these fibroblasts into induced pluripotent stem cells (iPSCs) resulted in the cell-autonomous correction of the ring chromosomal aberration via compensatory uniparental disomy (UPD). These observations have important implications for studying the mechanism of chromosomal number control and may lead to the development of effective therapies for other, more common, chromosomal aberrations. PMID:25482192

  6. Generic drug names and social welfare.

    PubMed

    Lobo, Flix; Feldman, Roger

    2013-06-01

    This article studies how well International Nonproprietary Names (INNs), the "generic" names for pharmaceuticals, address the problems of imperfect information. Left in private hands, the identification of medicines leads to confusion and errors. Developed in the 1950s by the World Health Organization, INNs are a common, global, scientific nomenclature designed to overcome this failure. Taking stock after sixty years, we argue that the contribution of INNs to social welfare is paramount. They enhance public health by reducing errors and improving patient safety. They also contribute to economic efficiency by creating transparency as the foundation of competitive generic drug markets, reducing transaction costs, and favoring trade. The law in most countries requires manufacturers to designate pharmaceuticals with INNs in labeling and advertising. Generic substitution is also permitted or mandatory in many countries. But not all the benefits of INNs are fully realized because prescribers may not use them. We advocate strong incentives or even legally binding provisions to extend the use of INNs by prescribing physicians and dispensing pharmacists, but we do not recommend replacing brand names entirely with INNs. Instead, we propose dual use of brand names and INNs in prescribing, as in drug labeling. PMID:23418366

  7. [Animal experimentation, animal welfare and scientific research].

    PubMed

    Tal, H

    2013-10-01

    Hundreds of thousands of laboratory animals are being used every year for scientific experiments held in Israel, mostly mice, rats, rabbits, guinea pigs, and a few sheep, cattle, pigs, cats, dogs, and even a few dozen monkeys. In addition to the animals sacrificed to promote scientific research, millions of animals slain every year for other purposes such as meat and fine leather fashion industries. While opening a front against all is an impossible and perhaps an unjustified task, the state of Israel enacted the Animal Welfare (Animal Experimentation) Law (1994). The law aims to regulate scientific animal experiments and to find the appropriate balance between the need to continue to perform animal experiments for the advancement of research and medicine, and at the same time to avoid unnecessary trials and minimize animal suffering. Among other issues the law deals with the phylogenetic scale according to which experimental animals should be selected, experiments for teaching and practicing, and experiments for the cosmetic industry. This article discusses bioethics considerations in animal experiments as well as the criticism on the scientific validity of such experiments. It further deals with the vitality of animal studies and the moral and legal obligation to prevent suffering from laboratory animals. PMID:24660572

  8. The map of chromosome 20.

    PubMed

    Simpson, N E

    1988-12-01

    The number of gene assignments to human chromosome 20 has increased slowly until recently. Only seven genes and one fragile site were confirmed assignments to chromosome 20 at the Ninth Human Gene Mapping Workshop in September 1987 (HGM9). One fragile site, 13 additional genes, and 10 DNA sequences that identify restriction fragment length polymorphisms (RFLPs), however, were provisionally added to the map at HGM9. Five mutated genes on chromosome 20 have a relation to disease: a mutation in the adenosine deaminase gene results in a deficiency of the enzyme and severe combined immune deficiency; mutations in the gene for the growth hormone releasing factor result in some forms of dwarfism; mutations in the closely linked genes for the hormones arginine vasopressin and oxytocin and their neurophysins are probably responsible for some diabetes insipidus; and mutations in the gene that regulates both alpha-neuraminidase and beta-galactosidase activities determine galactosialidosis. The gene for the prion protein is on chromosome 20; it is related to the infectious agent of kuru, Creutzfeld-Jacob disease, and Gertsmann-Straussler syndrome, although the nature of the relationship is not completely understood. Two genes that code for tyrosine kinases are on the chromosome, SRC1 the proto-oncogene and a gene (HCK) coding for haemopoietic kinase (an src-like kinase), but no direct relation to cancer has been shown for either of these kinases. The significance of non-random loss of chromosome 20 in the malignant diseases non-lymphocytic leukaemia and polycythaemia vera is not understood. Twenty-four additional loci are assigned to the chromosome: five genes that code for binding proteins, one for a light chain of ferritin, genes for three enzymes (inosine triphosphatase, s-adenosylhomocysteine hydrolase, and sterol delta 24-reductase), one for each of a secretory protein and an opiate neuropeptide, a cell surface antigen, two fragile sites, and 10 DNA sequences (one satellite and nine unique) that detect RFLPs. PMID:3070044

  9. Psychiatry, homeless patients and welfare reforms: historical links and chains.

    PubMed

    Abdul-Hamid, Walid Khalid; Bhui, Kamaldeep

    2014-02-01

    The birthplace of the specialty of psychiatry was in the asylum, which was created to divert patients from workhouses where the most disadvantaged and destitute people with mental illness were to be found. The current welfare reforms are endangering the welfare and livelihood of the most disadvantaged of our patients. These reforms in the authors' opinion are related more to the historical cycle of societal attitude to homeless people than to seeing them as the undeserving poor. This is particularly true since the current economic crisis was not caused by the poor, so it is very unfair that our poorest patients should suffer most as a result of the welfare reforms. PMID:23564721

  10. Simplifying the Welfare Quality® assessment protocol for broiler chicken welfare.

    PubMed

    de Jong, I C; Hindle, V A; Butterworth, A; Engel, B; Ferrari, P; Gunnink, H; Perez Moya, T; Tuyttens, F A M; van Reenen, C G

    2016-01-01

    Welfare Quality® (WQ) assessment protocols place the emphasis on animal-based measures as an indicator for animal welfare. Stakeholders, however, emphasize that a reduction in the time taken to complete the protocol is essential to improve practical applicability. We studied the potential for reduction in time to complete the WQ broiler assessment protocol and present some modifications to the protocol correcting a few errors in the original calculations. Data was used from 180 flocks assessed on-farm and 150 flocks assessed at the slaughter plant. Correlations between variables were calculated, and where correlation was moderate, meaningful and promising (in terms of time reduction), simplification was considered using one variable predicted from another variable. Correlation analysis revealed a promising correlation between severe hock burn and gait scores on-farm. Therefore, prediction of gait scores using hock burn scores was studied further as a possible simplification strategy (strategy 1). Measurements of footpad dermatitis, hock burn, cleanliness and gait score on-farm correlated moderately to highly with slaughter plant measurements of footpad dermatitis and/or hock burn, supporting substitution of on-farm measurements with slaughter plant data. A simplification analysis was performed using footpad dermatitis, hock burn, cleanliness and gait scores measured on-farm predicted from slaughter plant measurements of footpad dermatitis and hock burn (strategy 2). Simplification strategies were compared with the full assessment protocol. Close agreement was found between the full protocol and both simplification strategies although large confidence intervals were found for specificity of the simplified models. It is concluded that the proposed simplification strategies are encouraging; strategy 1 can reduce the time to complete the on-farm assessment by ~1 h (25% to 33% reduction) and strategy 2 can reduce on-farm assessment time by ~2 h (50% to 67% reduction). Both simplification strategies should, however, be validated further, and tested on farms with a wide distribution across the different welfare categories of WQ. PMID:26306882

  11. Chromosome imbalances associated with epilepsy.

    PubMed

    Schinzel, A; Niedrist, D

    2001-01-01

    Epilepsy is among the most frequent findings in many, especially autosomal, chromosome aberrations. Its incidence, however, is very variable, and there are very few aberrations in which epilepsy is a constant finding. Even siblings and monozygotic twins with the same aberration are often discordant for seizure disorders. Similar observations can be made for congenital (major) malformations in chromosome aberrations. The common explanation is that in these instances epilepsy is not caused by the action of a single gene in single or triple dose, but is influenced by the combined action of a number of genes within and outside of the aneuploid segment. The situation is comparable to a polygenic model of inheritance. Gene mutations associated with epilepsy are known, to date, only for two disorders: the lissencephaly 1 gene in Miller-Dieker syndrome and mutations in the UBE3A gene in Angelman syndrome. Chromosome aberrations in which epilepsy is a major and consistent finding include Angelman syndrome due to loss of the maternal 15q11.2-q12 segment, tetrasomy of the maternal segment 15pter-q13 due to an additional inv dup chromosome, Miller-Dieker syndrome due to deletion of the 17p13.3 segment including the lissencephaly1 gene, ring chromosome 20, and Wolf-Hirschhorn syndrome due to deletion of at least the 4p16.3 segment. PMID:11579431

  12. Chromosome segregation in plant meiosis

    PubMed Central

    Zamariola, Linda; Tiang, Choon Lin; De Storme, Nico; Pawlowski, Wojtek; Geelen, Danny

    2014-01-01

    Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating aneuploid or polyploid progeny, respectively. Accurate segregation requires the coordinated execution of conserved processes occurring throughout the two meiotic cell divisions. Synapsis and recombination ensure the establishment of chiasmata that hold homologous chromosomes together allowing their correct segregation in the first meiotic division, which is also tightly regulated by cell-cycle dependent release of cohesin and monopolar attachment of sister kinetochores to microtubules. In meiosis II, bi-orientation of sister kinetochores and proper spindle orientation correctly segregate chromosomes in four haploid cells. Checkpoint mechanisms acting at kinetochores control the accuracy of kinetochore-microtubule attachment, thus ensuring the completion of segregation. Here we review the current knowledge on the processes taking place during chromosome segregation in plant meiosis, focusing on the characterization of the molecular factors involved. PMID:24987397

  13. Condensin: crafting the chromosome landscape.

    PubMed

    Piazza, Ilaria; Haering, Christian H; Rutkowska, Anna

    2013-06-01

    The successful transmission of complete genomes from mother to daughter cells during cell divisions requires the structural re-organization of chromosomes into individualized and compact structures that can be segregated by mitotic spindle microtubules. Multi-subunit protein complexes named condensins play a central part in this chromosome condensation process, but the mechanisms behind their actions are still poorly understood. An increasing body of evidence suggests that, in addition to their role in shaping mitotic chromosomes, condensin complexes have also important functions in directing the three-dimensional arrangement of chromatin fibers within the interphase nucleus. To fulfill their different functions in genome organization, the activity of condensin complexes and their localization on chromosomes need to be strictly controlled. In this review article, we outline the regulation of condensin function by phosphorylation and other posttranslational modifications at different stages of the cell cycle. We furthermore discuss how these regulatory mechanisms are used to control condensin binding to specific chromosome domains and present a comprehensive overview of condensin's interaction partners in these processes. PMID:23546018

  14. Disorders caused by chromosome abnormalities

    PubMed Central

    Theisen, Aaron; Shaffer, Lisa G

    2010-01-01

    Many human genetic disorders result from unbalanced chromosome abnormalities, in which there is a net gain or loss of genetic material. Such imbalances often disrupt large numbers of dosage-sensitive, developmentally important genes and result in specific and complex phenotypes. Alternately, some chromosomal syndromes may be caused by a deletion or duplication of a single gene with pleiotropic effects. Traditionally, chromosome abnormalities were identified by visual inspection of the chromosomes under a microscope. The use of molecular cytogenetic technologies, such as fluorescence in situ hybridization and microarrays, has allowed for the identification of cryptic or submicroscopic imbalances, which are not visible under the light microscope. Microarrays have allowed for the identification of numerous new syndromes through a genotype-first approach in which patients with the same or overlapping genomic alterations are identified and then the phenotypes are described. Because many chromosomal alterations are large and encompass numerous genes, the ascertainment of individuals with overlapping deletions and varying clinical features may allow researchers to narrow the region in which to search for candidate genes. PMID:23776360

  15. Chromosomal abnormalities in human sperm

    SciTech Connect

    Martin, R.H.

    1985-01-01

    The ability to analyze human sperm chromosome complements after penetration of zona pellucida-free hamster eggs provides the first opportunity to study the frequency and type of chromosomal abnormalities in human gametes. Two large-scale studies have provided information on normal men. We have studied 1,426 sperm complements from 45 normal men and found an abnormality rate of 8.9%. Brandriff et al. (5) found 8.1% abnormal complements in 909 sperm from 4 men. The distribution of numerical and structural abnormalities was markedly dissimilar in the 2 studies. The frequency of aneuploidy was 5% in our sample and only 1.6% in Brandriff's, perhaps reflecting individual variability among donors. The frequency of 24,YY sperm was low: 0/1,426 and 1/909. This suggests that the estimates of nondisjunction based on fluorescent Y body data (1% to 5%) are not accurate. We have also studied men at increased risk of sperm chromosomal abnormalities. The frequency of chromosomally unbalanced sperm in 6 men heterozygous for structural abnormalities varied dramatically: 77% for t11;22, 32% for t6;14, 19% for t5;18, 13% for t14;21, and 0% for inv 3 and 7. We have also studied 13 cancer patients before and after radiotherapy and demonstrated a significant dose-dependent increase of sperm chromosome abnormalities (numerical and structural) 36 months after radiation treatment.

  16. Structure and function of eukaryotic chromosomes

    SciTech Connect

    Hennig, W.

    1987-01-01

    Contents: Introduction; Polytene Chromosomel Giant Chromosomes in Ciliates; The sp-I Genes in the Balbiani Rings of Chironomus Salivary Glands; The White Locus of Drosophila Melanogaster; The Genetic and Molecular Organization of the Dense Cluster of Functionally Related Vital Genes in the DOPA Decarboxylase Region of the Drosophila melanogaster Genome; Heat Shock Puffs and Response to Environmental Stress; The Y Chromosomal Lampbrush Loops of Drosophila; Contributions of Electron Microscopic Spreading Preparations (''Miller Spreads'') to the Analysis of Chromosome Structure; Replication of DNA in Eukaryotic Chromosomes; Gene Amplification in Dipteran Chromosomes; The Significance of Plant Transposable Elements in Biologically Relevant Processes; Arrangement of Chromosomes in Interphase Cell Nuclei; Heterochromatin and the Phenomenon of Chromosome Banding; Multiple Nonhistone Protein-DNA Complexes in Chromatin Regulate the Cell- and Stage-Specific Activity of an Eukaryotic Gene; Genetics of Sex Determination in Eukaryotes; Application of Basic Chromosome Research in Biotechnology and Medicine. This book presents an overview of various aspects of chromosome research.

  17. Health insurance and access to care among welfare leavers.

    PubMed

    Danziger, Sheldon; Davis, Matthew M; Orzol, Sean; Pollack, Harold A

    2008-01-01

    This analysis explores the effects of the 1996 welfare reform on health insurance coverage and access to care among former recipients of cash aid. Using panel data from the Women's Employment Study, which conducted five interviews between 1997 and 2003 in one Michigan county, we find that 25% of welfare leavers lacked health insurance coverage in fall 2003. Uninsured adults were significantly more likely than others to report that they could not afford a medical or dental visit during the year prior to the 2003 interview. Fixed-effect logistic regression analysis indicates that women who had been off the welfare rolls for at least 12 months (the duration of transitional Medicaid) were significantly more likely to be uninsured than women who had made more recent welfare exits, and were significantly more likely to report financial obstacles to the receipt of medical and dental care. PMID:18767383

  18. Welfare reforms in Australia: how will they affect women's health?

    PubMed

    Kelaher, Margaret; Manderson, Lenore; Stellman, Jeanne Mager

    2002-01-01

    Like most Western countries, Australia is in the process of introducing welfare reforms to curb costs. Australian reforms follow and are informed by similar reforms in the United States and United Kingdom and will be incrementally implemented until 2003. Australian reforms emphasize mutual obligation, preventing people from "taking advantage" of the welfare system, and avoiding long-term reliance on welfare. In contrast to the United States, where the mothers of young children have specifically been targeted, reforms in Australia do not privilege women's roles as workers over their roles as caregivers. Work obligations will be introduced only for mothers whose youngest child is older than 16 years. In fact, financial incentives for providing care for young children and people with disabilities have actually increased. Existing health research suggests that the impact of welfare reform on both health and society will depend on how the balance between women's roles as caregivers and workers is struck. PMID:11905493

  19. The Impacts of Climate Change Mitigation Strategies on Animal Welfare.

    PubMed

    Shields, Sara; Orme-Evans, Geoffrey

    2015-01-01

    The objective of this review is to point out that the global dialog on reducing greenhouse gas emissions in animal agriculture has, thus far, not adequately considered animal welfare in proposed climate change mitigation strategies. Many suggested approaches for reducing emissions, most of which could generally be described as calls for the intensification of production, can have substantial effects on the animals. Given the growing world-wide awareness and concern for animal welfare, many of these approaches are not socially sustainable. This review identifies the main emission abatement strategies in the climate change literature that would negatively affect animal welfare and details the associated problems. Alternative strategies are also identified as possible solutions for animal welfare and climate change, and it is suggested that more attention be focused on these types of options when allocating resources, researching mitigation strategies, and making policy decisions on reducing emissions from animal agriculture. PMID:26479240

  20. Uruguay: Population Geography of a Troubled Welfare State

    ERIC Educational Resources Information Center

    Tata, Robert J.

    1977-01-01

    Discussed is whether or not Uruguay's elaborate welfare system can be maintained by a deteriorating economy plagued by social tension and political unrest. Historical background is presented, demographic variables are discussed and modern influences are measured. (Author/DB)

  1. Welfare Impacts of Pindone Poisoning in Rabbits (Oryctolagus cuniculus).

    PubMed

    Fisher, Penny; Brown, Samantha; Arrow, Jane

    2016-01-01

    Control methods used to manage unwanted impacts of the European rabbit in Australia and New Zealand include the use of toxic bait containing the anticoagulant pindone. Towards increased certainty in evaluating the animal welfare impacts of pindone poisoning in rabbits, we recorded behavioral and post-mortem data from rabbits which ingested lethal quantities of pindone bait in a laboratory trial. Pindone poisoning in rabbits resulted in welfare compromise, primarily through functional impairments related to internal haemorrhage over a maximum duration of 7 days. Applying this data to a formal assessment framework for ranking animal welfare impacts indicated that pindone had relatively high severity and also duration of welfare impacts in comparison to other rabbit control methods. PMID:26927192

  2. Safeguarding the welfare of farmed fish at harvest.

    PubMed

    Lines, J A; Spence, J

    2012-02-01

    Fish welfare at harvest is easily compromised by poor choice of handling and slaughter methods, lack of attention to detail and by unnecessary adherence to fish farming traditions. The harvest process comprises fasting the fish to empty the gut, crowding the fish, gathering and moving the fish using brails, fish pumps, and sometimes also road or boat transport and finally stunning and killing the fish. The harvesting processes commonly used for bass, bream, carp, catfish, cod, eel, halibut, pangasius, salmon, tilapia, trout, tuna and turbot are outlined. These harvesting processes are discussed; the consequences for fish welfare identified and practical tests which can be made at the harvest site highlighted. Welfare at harvest for the majority of farmed fish species can be improved by adopting and adapting existing procedures already known to be beneficial for fish welfare through their use in other fish farming systems or with other species. It is seldom necessary to develop completely new concepts or methods. PMID:21989953

  3. Welfare reform: advocacy and intervention in the health care setting.

    PubMed Central

    Lawton, E; Leiter, K; Todd, J; Smith, L

    1999-01-01

    Welfare reform has drastically altered the lives of poor families in the US. In its wake, many former recipients are not receiving whatever transitional benefits and other safeguards to which they remain entitled under federal and state laws. Families are losing access to Medicaid and are not receiving the child care assistance or Food Stamps for which they continue to be eligible. Ill-served by stringent time limits and work requirements, lack of child care assistance, and lack of training and educational opportunities for the development of skills that will lead to better jobs, families need help to navigate the complexities of the new welfare system. Boston Medical Center's Department of Pediatrics has instituted a welfare screening project to educate families about their rights under welfare reform and assist them in advocating for themselves and their children. PMID:10670622

  4. The politics of welfare privatization: the British experience.

    PubMed

    Taylor-Gooby, P

    1989-01-01

    The 1980s Conservative government in Britain is committed to policies of welfare privatization for practical and ideological reasons--to facilitate tax cuts and to roll back the state. One problem this policy faces is that the most expensive and interventionist services are highly popular with voters from all parties. In this article, the author examines the extent to which recent privatization policies in welfare are influenced by conflict between the goals of achieving tax cuts and of maintaining electoral support, so that the outcome is a change in the form of state interventionism, rather than a rolling back of the welfare state. It also considers the impact of new policies designed to undermine the consensus across social groups and political parties of support for big-spending state services, which may facilitate reductions in the overall scope of welfare provision in future years. PMID:2714921

  5. Heterogeneous Risk Preferences and the Welfare Cost of Business Cycles

    PubMed Central

    Schulhofer-Wohl, Sam

    2009-01-01

    I study the welfare cost of business cycles in a complete-markets economy where some people are more risk averse than others. Relatively more risk-averse people buy insurance against aggregate risk, and relatively less risk-averse people sell insurance. These trades reduce the welfare cost of business cycles for everyone. Indeed, the least risk-averse people benefit from business cycles. Moreover, even infinitely risk-averse people suffer only finite and, in my empirical estimates, very small welfare losses. In other words, when there are complete insurance markets, aggregate fluctuations in consumption are essentially irrelevant not just for the average person the surprising finding of Lucas (1987) but for everyone in the economy, no matter how risk averse they are. If business cycles matter, it is because they affect productivity or interact with uninsured idiosyncratic risk, not because aggregate risk per se reduces welfare. PMID:21709768

  6. Public Welfare Agenda or Corporate Research Agenda?

    PubMed Central

    Singh, Ajai; Singh, Shakuntala

    2005-01-01

    As things stand today, whether we like it or not, industry funding is on the upswing. The whole enterprise of medicine in booming, and it makes sense for industry to invest more and more of one's millions into it. The pharmaceutical industry has become the single largest direct funding agency of medical research in countries like Canada, the United Kingdom and the United States. Since the goals of industry and academia differ, it seems that conflicts of interest are inevitable at times. The crucial decision is whether the public welfare agenda of academia, or the corporate research agenda of industry, should occupy center stage when they conflict. There is enough evidence to show that funding by industry is very systematic, and results that are supportive of the safety and efficacy of sponsor's products alone get the funds. It is no surprise, therefore, that one finds very few negative drug trials reports published, and whatever are, are likely to be by rival companies to serve their commercial interests. Renewed and continued funding by industry decides the future prospects of many academic researchers. At the same time there is now evidence that pharmaceutical companies attempt suppression of research findings, may be selective in publishing results, and may delay or stymie publication of unfavourable results. This is a major area of concern for all conscientious researchers and industry watchers. Industry commonly decides which clinical research/trial gets done, not academia, much though the latter may wish to believe otherwise. It finds willing researchers to carry this out. This can be one area of concern. Another area of pressing concern is when industry decides to both design and control publication of research. It makes sense for researchers to refuse to allow commercial interests to rule research reporting. Research having been reported, the commercial implications of such reporting is industry's concern. But, doctoring of findings to suit commerce is to be resisted at all costs. In this even pliant researchers need have no fear, for if they indeed publish what will work, the concerned sponsor will benefit in the long run. The only decision academia has to make is refuse to comply with predestined conclusions of sponsors for the ‘thirty pieces of silver’. Instead do genuine research and make sixty for themselves. The useful rule of thumb is: Keep the critical antenna on, especially with regard to drug trials, and more especially their methodology, and study closely the conflict of interest disclosed, and if possible undisclosed, before you jump on the band wagon to herald the next great wonder drug. There are three important lessons to be learnt by academia in all academia-industry relationships: i)Lesson number one: incorporate the right to publish contrary findings in the research contract itself. Which means, it makes great sense for academia to concentrate on the language and contractual provisions of sponsored research, to read the fine print very closely, and protect their research interests in case of conflict.ii)Lesson number two: a number of lawsuits successfully brought up against industry recently reflect earnest attempts by patient welfare bodies and others to remedy the tilt. It will result in a newfound confidence in academia that augurs well for academia industry relationship in the long run. Hence the second lesson for academia: do not get browbeaten by threats of legal actioniii)Lesson number three: Academia should keep itself involved right from inception of the clinical trial through to ultimate publication. And this must be an integral part of the written contract. The time to repeat cliches about the exciting future of the academia-industry connect is past. A concerted effort to lay a strong foundation of the relationship on practical ethical grounds has become mandatory. PMID:22679348

  7. Oral Gavage in Rats: Animal Welfare Evaluation

    PubMed Central

    Turner, Patricia V; Vaughn, Elizabeth; Sunohara-Neilson, Janet; Ovari, Jelena; Leri, Francesco

    2012-01-01

    The effect of chronic daily orogastric gavage with water (5 mL/kg) on behavior and physiology was evaluated in male SpragueDawley rats. Treatment groups included: unmanipulated control, restraint control, dry gavage, and gavage, with all rats singly housed (n = 9 or 10 per group). In addition, a group of pair-housed rats (n = 18) was included to determine whether social housing affected response to gavage. Weekly body weights and food consumption were recorded as well as use of a nylon chew toy for enrichment. Feces were collected biweekly at the end of the light and dark phases for fecal corticoid metabolite determinations. After 28 d of treatment, animals underwent conditioned place preference testing to evaluate sensitivity to motivational properties of the anxiolytic drug chlordiazepoxide (5.6 mg/kg SC). Brain and paired adrenal gland weights were collected at necropsy. Week 2 total fecal corticosterone levels were elevated in all groups and attributed to a fire alarm accidentally tripped during building renovations. No differences occurred in body weight or food consumption between any groups. All groups used a nylon chew toy given for enrichment and demonstrated mild preference for the drug-associated chamber. Fecal weights and corticoid metabolite levels were similar between all groups at week 4 and showed normal diurnal variation. No biologically significant variations were noted in brain or paired adrenal gland to body weight ratios. We conclude that orogastric gavage of aqueous solutions at 5 mL/kg does not negatively affect the welfare of laboratory rats acclimated to handling. PMID:22330864

  8. Oral gavage in rats: animal welfare evaluation.

    PubMed

    Turner, Patricia V; Vaughn, Elizabeth; Sunohara-Neilson, Janet; Ovari, Jelena; Leri, Francesco

    2012-01-01

    The effect of chronic daily orogastric gavage with water (5 mL/kg) on behavior and physiology was evaluated in male Sprague-Dawley rats. Treatment groups included: unmanipulated control, restraint control, dry gavage, and gavage, with all rats singly housed (n = 9 or 10 per group). In addition, a group of pair-housed rats (n = 18) was included to determine whether social housing affected response to gavage. Weekly body weights and food consumption were recorded as well as use of a nylon chew toy for enrichment. Feces were collected biweekly at the end of the light and dark phases for fecal corticoid metabolite determinations. After 28 d of treatment, animals underwent conditioned place preference testing to evaluate sensitivity to motivational properties of the anxiolytic drug chlordiazepoxide (5.6 mg/kg SC). Brain and paired adrenal gland weights were collected at necropsy. Week 2 total fecal corticosterone levels were elevated in all groups and attributed to a fire alarm accidentally tripped during building renovations. No differences occurred in body weight or food consumption between any groups. All groups used a nylon chew toy given for enrichment and demonstrated mild preference for the drug-associated chamber. Fecal weights and corticoid metabolite levels were similar between all groups at week 4 and showed normal diurnal variation. No biologically significant variations were noted in brain or paired adrenal gland to body weight ratios. We conclude that orogastric gavage of aqueous solutions at 5 mL/kg does not negatively affect the welfare of laboratory rats acclimated to handling. PMID:22330864

  9. Sex chromosome tetrasomy and pentasomy.

    PubMed

    Linden, M G; Bender, B G; Robinson, A

    1995-10-01

    Sex chromosome abnormalities occur in at least 1 in 400 births and include the well-described 47,XXX, 47,XXY, 47,XYY, and 45,X karyotypes. The addition of more than one extra X or Y chromosome occurs rarely, and little information is available in the medical literature. Individual case reports make up most of this body of knowledge, and all are based on subjects who identified themselves postnatally. Many were ascertained through screenings of institutions and hospitals; thus, there is no unbiased information on the natural history of poly X and Y karyotypes. A direct relationship between the number of additional sex chromosomes and the severity of the phenotype is generally assumed. The purpose of this article is to summarize what is known about these conditions and to present 10 additional cases. The karyotypes include, 48,XXXX, 49,XXXXX, 48,XXYY, 48,XXXY, 49,XXXXY, 49,XXXYY, 48,XYYY, 49,XYYYY, and 49,XXYYY. PMID:7567329

  10. Equipment Failure Analysis

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Tennessee Eastman uses NASTRAN to minimize lost production by pinpointing the causes of equipment failures and preventing recurrences. An example of the program's utility involves a large centrifugal fan which developed cracks during start-ups and shutdowns. This information prompted redesign of the fan. Tennessee Eastman has made extensive use of NASTRAN, both as failure analysis tool and as an aid in redesigning production hardware.

  11. Applying ethological and health indicators to practical animal welfare assessment.

    PubMed

    Wemelsfelder, F; Mullan, S

    2014-04-01

    There is a growing effort worldwide to develop objective indicators for animal welfare assessment, which provide information on an animal's quality of life, are scientifically trustworthy, and can readily be used in practice by professionals. Animals are sentient beings capable of positive and negative emotion, and so these indicators should be sensitive not only to their physical health, but also to their experience of the conditions in which they live. This paper provides an outline of ethological research aimed at developing practical welfare assessment protocols. The first section focuses on the development and validation of welfare indicators generally, in terms of their relevance to animal well-being, their interobserver reliability, and the confidence with which the prevalence of described features can be estimated. Challenges in this work include accounting for the ways in which welfare measures may fluctuate over time, and identifying measures suited to monitoring positive welfare states. The second section focuses more specifically on qualitative welfare indicators, which assess the 'whole animal' and describe the expressive qualities of its demeanour (e.g. anxious, content). Such indicators must be validated in the same way as other health and behaviour indicators, with the added challenge of finding appropriate methods of measurement. The potential contribution of qualitative indicators, however, is to disclose an emotional richness in animals that helps to interpret information provided by other indicators, thus enhancing the validity of welfare assessment protocols. In conclusion, the paper emphasises the importance of integrating such different perspectives, showing that new knowledge of animals and new ways of relating to animals are both needed for the successful development of practical welfare assessment tools. PMID:25000783

  12. Child welfare employee recruitment and retention: an organizational culture perspective.

    PubMed

    Agbnyiga, DeBrenna LaFa

    2009-01-01

    Drawing data from an organizational culture study, this cross-sectional study investigates the effect of organizational culture on child welfare employee recruitment and retention (N=92). Findings from quantitative analyses of the organizational culture inventory suggest that constructive culture style in child welfare organizations, especially humanistic-encouraging and self-actualizing culture norms, highly predict recruitment through employees' perception of "fit" and satisfaction as a member of the organization. Limitations, future research, and relevant implications are discussed. PMID:20695293

  13. Secure authenticated video equipment

    SciTech Connect

    Doren, N.E.

    1993-07-01

    In the verification technology arena, there is a pressing need for surveillance and monitoring equipment that produces authentic, verifiable records of observed activities. Such a record provides the inspecting party with confidence that observed activities occurred as recorded, without undetected tampering or spoofing having taken place. The secure authenticated video equipment (SAVE) system provides an authenticated series of video images of an observed activity. Being self-contained and portable, it can be installed as a stand-alone surveillance system or used in conjunction with existing monitoring equipment in a non-invasive manner. Security is provided by a tamper-proof camera enclosure containing a private, electronic authentication key. Video data is transferred communication link consisting of a coaxial cable, fiber-optic link or other similar media. A video review station, located remotely from the camera, receives, validates, displays and stores the incoming data. Video data is validated within the review station using a public key, a copy of which is held by authorized panics. This scheme allows the holder of the public key to verify the authenticity of the recorded video data but precludes undetectable modification of the data generated by the tamper-protected private authentication key.

  14. Consumers and animal welfare. A comparison between European Union countries.

    PubMed

    Toma, Luiza; Stott, Alistair W; Revoredo-Giha, Cesar; Kupiec-Teahan, Beata

    2012-04-01

    This paper analyses the impact of a priori identified determinants on stated willingness to change usual place of shopping in order to be able to buy more animal welfare friendly food products of consumers in nine European Union countries. We used Eurobarometer data and structural equation models with observed and latent variables. The results show that the ranking of determinants' impact on the behavioural willingness is similar in the majority of models, with access to information as the strongest determinant, followed by perceived responsibility of consumers and education with strong influence, then by labelling and occupation with lower impact and ending with children, with the lowest influence. This study aims to provide some evidence on the relationship between welfare friendly behavioural willingness and information and labelling issues, amongst other determinants, in the European Union. As both access to information and perception of welfare labelling were found to significantly influence the behavioural willingness, this might suggest the need for the European Union to invest more in improving the welfare labelling system, enhance the welfare information available to the public and improve access to it through measures such as welfare education campaigns. PMID:22127269

  15. Evolution of cooperation driven by social-welfare-based migration

    NASA Astrophysics Data System (ADS)

    Li, Yan; Ye, Hang; Zhang, Hong

    2016-03-01

    Individuals' migration behavior may play a significant role in the evolution of cooperation. In reality, individuals' migration behavior may depend on their perceptions of social welfare. To study the relationship between social-welfare-based migration and the evolution of cooperation, we consider an evolutionary prisoner's dilemma game (PDG) in which an individual's migration depends on social welfare but not on the individual's own payoff. By introducing three important social welfare functions (SWFs) that are commonly studied in social science, we find that social-welfare-based migration can promote cooperation under a wide range of parameter values. In addition, these three SWFs have different effects on cooperation, especially through the different spatial patterns formed by migration. Because the relative efficiency of the three SWFs will change if the parameter values are changed, we cannot determine which SWF is optimal for supporting cooperation. We also show that memory capacity, which is needed to evaluate individual welfare, may affect cooperation levels in opposite directions under different SWFs. Our work should be helpful for understanding the evolution of human cooperation and bridging the chasm between studies of social preferences and studies of social cooperation.

  16. Assessing animal welfare: different philosophies, different scientific approaches.

    PubMed

    Fraser, David

    2009-11-01

    Attempts to improve animal welfare have commonly centered around three broad objectives: (1) to ensure good physical health and functioning of animals, (2) to minimize unpleasant "affective states" (pain, fear, etc.) and to allow animals normal pleasures, and (3) to allow animals to develop and live in ways that are natural for the species. Each of these objectives has given rise to scientific approaches for assessing animal welfare. An emphasis on health and functioning has led to assessment methods based on rates of disease, injury, mortality, and reproductive success. An emphasis on affective states has led to assessment methods based on indicators of pain, fear, distress, frustration and similar experiences. An emphasis on natural living has led to research on the natural behavior of animals and on the strength of animals' motivation to perform different elements of their behavior. All three approaches have yielded practical ways to improve animal welfare, and the three objectives are often correlated. However, under captive conditions, where the evolved adaptations of animals may not match the challenges of their current circumstances, the single-minded pursuit of any one criterion may lead to poor welfare as judged by the others. Furthermore, the three objectives arise from different philosophical views about what constitutes a good life-an area of disagreement that is deeply embedded in Western culture and that is not resolved by scientific research. If efforts to improve animal welfare are to achieve widespread acceptance, they need to strike a balance among the different animal welfare objectives. PMID:19434682

  17. Array painting: a protocol for the rapid analysis of aberrant chromosomes using DNA microarrays

    PubMed Central

    Gribble, Susan M; Ng, Bee Ling; Prigmore, Elena; Fitzgerald, Tomas; Carter, Nigel P

    2012-01-01

    Aarray painting is a technique that uses microarray technology to rapidly map chromosome translocation breakpoints. previous methods to map translocation breakpoints have used fluorescence in situ hybridization (FIsH) and have consequently been labor-intensive, time-consuming and restricted to the low breakpoint resolution imposed by the use of metaphase chromosomes. array painting combines the isolation of derivative chromosomes (chromosomes with translocations) and high-resolution microarray analysis to refine the genomic location of translocation breakpoints in a single experiment. In this protocol, we describe array painting by isolation of derivative chromosomes using a MoFlo flow sorter, amplification of these derivatives using whole-genome amplification and hybridization onto commercially available oligonucleotide microarrays. although the sorting of derivative chromosomes is a specialized procedure requiring sophisticated equipment, the amplification, labeling and hybridization of Dna is straightforward, robust and can be completed within 1 week. the protocol described produces good quality data; however, array painting is equally achievable using any combination of the available alternative methodologies for chromosome isolation, amplification and hybridization. PMID:19893508

  18. Multiscale image enhancement of chromosome banding patterns

    NASA Astrophysics Data System (ADS)

    Wu, Qiang; Castleman, Kenneth R.

    1996-10-01

    Visual examination of chromosome banding patterns is an important means of chromosome analysis. Cytogeneticists compare their patient's chromosome image against the prototype normal/abnormal human chromosome banding patterns. Automated chromosome analysis instruments facilitate this by digitally enhancing the chromosome images. Currently available systems employing traditional highpass/bandpass filtering and/or histogram equalization are approximately equivalent to photomicroscopy in their ability to support the detection of band pattern alterations. Improvements in chromosome image display quality, particularly in the detail of the banding pattern, would significantly increase the cost-effectiveness of these systems. In this paper we present our work on the use of multiscale transform and derivative filtering for image enhancement of chromosome banding patterns. A steerable pyramid representation of the chromosome image is generated by a multiscale transform. The derivative filters are designed to detect the bands of a chromosome, and the steerable pyramid transform is chosen based on its desirable properties of shift and rotation invariance. By processing the transform coefficients that correspond to the bands of the chromosome in the pyramid representation, contrast enhancement of the chromosome bands can be achieved with designed flexibility in scale, orientation and location. Compared with existing chromosome image enhancement techniques, this new approach offers the advantage of selective chromosome banding pattern enhancement that allows designated detail analysis. Experimental results indicate improved enhancement capabilities and promise more effective visual aid to comparison of chromosomes to the prototypes and to each other. This will increase the ability of automated chromosome analysis instruments to assist the evaluation of chromosome abnormalities in clinical samples.

  19. From welfare states to welfare sectors: Explaining sectoral differences in occupational pensions with economic and political power of employees

    PubMed Central

    Wiß, Tobias

    2015-01-01

    Studies analysing welfare have previously focused on countries as units. In the course of pension cuts and the increasing importance of occupational welfare, our traditional understanding of a homogeneous welfare state is being challenged. In this article, I distinguish between both economic individual power (employee skills) and political collective power (trade unions), and their relation with different occupational pensions. A combined analysis by both factors is not common, where employee skills and power resources are traditionally treated as separate, rival explanations of public welfare. Combining the ‘method of difference’ with the ‘method of agreement’, the article first presents the within-country variety of occupational pensions in Germany, Italy, the United Kingdom and Denmark. Occupational pensions in the same economic sectors across countries are then used as the units of analysis in order to illustrate the plausible determinants of economic individual power and political collective power. PMID:26663983

  20. Good animal welfare makes economic sense: potential of pig abattoir meat inspection as a welfare surveillance tool

    PubMed Central

    2012-01-01

    During abattoir meat inspection pig carcasses are partially or fully condemned upon detection of disease that poses a risk to public health or welfare conditions that cause animal suffering e.g. fractures. This incurs direct financial losses to producers and processors. Other health and welfare-related conditions may not result in condemnation but can necessitate ‘trimming’ of the carcass e.g. bruising, and result in financial losses to the processor. Since animal health is a component of animal welfare these represent a clear link between suboptimal pig welfare and financial losses to the pig industry. Meat inspection data can be used to inform herd health programmes, thereby reducing the risk of injury and disease and improving production efficiency. Furthermore, meat inspection has the potential to contribute to surveillance of animal welfare. Such data could contribute to reduced losses to producers and processors through lower rates of carcass condemnations, trimming and downgrading in conjunction with higher pig welfare standards on farm. Currently meat inspection data are under-utilised in the EU, even as a means of informing herd health programmes. This includes the island of Ireland but particularly the Republic. This review describes the current situation with regard to meat inspection regulation, method, data capture and utilisation across the EU, with special reference to the island of Ireland. It also describes the financial losses arising from poor animal welfare (and health) on farms. This review seeks to contribute to efforts to evaluate the role of meat inspection as a surveillance tool for animal welfare on-farm, using pigs as a case example. PMID:22738170

  1. 8. CONTROL AND EQUIPMENT ROOM INTERIOR. MECHANICAL EQUIPMENT ROOM AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. CONTROL AND EQUIPMENT ROOM INTERIOR. MECHANICAL EQUIPMENT ROOM AT RIGHT AND ENTRANCE AT LEFT. Looking east. - Edwards Air Force Base, South Base Sled Track, Firing Control Blockhouse, South of Sled Track at east end, Lancaster, Los Angeles County, CA

  2. 12. VIEW OF REMOTELY OPERATED EQUIPMENT. OPERATORS VIEWED THE EQUIPMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. VIEW OF REMOTELY OPERATED EQUIPMENT. OPERATORS VIEWED THE EQUIPMENT THROUGH A WATER-FILLED WINDOW. (10/8/81) - Rocky Flats Plant, Plutonium Recovery Facility, Northwest portion of Rocky Flats Plant, Golden, Jefferson County, CO

  3. 45 CFR 400.112 - Child welfare services for refugee children.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 2 2013-10-01 2012-10-01 true Child welfare services for refugee children. 400... RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Child Welfare Services § 400.112 Child welfare services for refugee children. (a)...

  4. 45 CFR 400.112 - Child welfare services for refugee children.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Child welfare services for refugee children. 400... RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Child Welfare Services § 400.112 Child welfare services for refugee children. (a)...

  5. 45 CFR 400.112 - Child welfare services for refugee children.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Child welfare services for refugee children. 400... RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Child Welfare Services § 400.112 Child welfare services for refugee children. (a)...

  6. 45 CFR 400.112 - Child welfare services for refugee children.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Child welfare services for refugee children. 400... RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Child Welfare Services § 400.112 Child welfare services for refugee children. (a)...

  7. 45 CFR 400.112 - Child welfare services for refugee children.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 2 2012-10-01 2012-10-01 false Child welfare services for refugee children. 400... RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Child Welfare Services § 400.112 Child welfare services for refugee children. (a)...

  8. Effects of Welfare Reform on Vocational Education and Training. NBER Working Paper No. 16659

    ERIC Educational Resources Information Center

    Dave, Dhaval M.; Reichman, Nancy E.; Corman, Hope; Das, Dhiman

    2011-01-01

    Exploiting variation in welfare reform across states and over time and using relevant comparison groups, this study estimates the effects of welfare reform on an important source of human capital acquisition among women at risk for relying on welfare: vocational education and training. The results indicate that welfare reform reduced enrollment in…

  9. 34 CFR 104.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Health, welfare, and other social services. 104.52... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services 104.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits,...

  10. 34 CFR 104.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Health, welfare, and other social services. 104.52... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services 104.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits,...

  11. Welfare Reform's Impact on Adolescents: Early Warning Signs. Child Trends Research Brief.

    ERIC Educational Resources Information Center

    Brooks, Jennifer L.; Hair, Elizabeth C.; Zaslow, Martha J.

    With the passage of the 1996 welfare reform law, numerous commentators expressed concern about the impact of welfare reform on young children of welfare recipients, while few expressed concern about adolescents. However, recent evidence suggests that adolescents are affected negatively when their parents participate in welfare-to-work programs.

  12. Employment as a "Solution" to Welfare: Challenges over the Next Ten Years.

    ERIC Educational Resources Information Center

    Bartik, Timothy J.

    2000-01-01

    Recent reforms assume that welfare recipients can achieve employment if welfare agencies just give them a "push". Over the next ten years, the "employment solution" to welfare faces the following three challenges: (1) employing all employable welfare recipients; (2) helping them get and keep good jobs; and (3) reconstructing a safety net for those

  13. The Colonization of (M)Others in Welfare-to-Work Education.

    ERIC Educational Resources Information Center

    Bloom, Leslie Rebecca; Kilgore, Deborah

    2003-01-01

    Argues that welfare reform policies colonize poor mothers. Using ethnographic data of a welfare-to-work educational program, analyzes how colonizing public and governmental discourses about welfare mothers infiltrate the program's educational policy and everyday practices. Asserts that welfare-to-work neither fully colonizes nor fully educates,…

  14. 34 CFR 104.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Health, welfare, and other social services. 104.52... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services 104.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits,...

  15. 34 CFR 104.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Health, welfare, and other social services. 104.52... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services 104.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits,...

  16. 34 CFR 104.52 - Health, welfare, and other social services.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Health, welfare, and other social services. 104.52... FEDERAL FINANCIAL ASSISTANCE Health, Welfare, and Social Services 104.52 Health, welfare, and other social services. (a) General. In providing health, welfare, or other social services or benefits,...

  17. Effects of Welfare Reform on Vocational Education and Training. NBER Working Paper No. 16659

    ERIC Educational Resources Information Center

    Dave, Dhaval M.; Reichman, Nancy E.; Corman, Hope; Das, Dhiman

    2011-01-01

    Exploiting variation in welfare reform across states and over time and using relevant comparison groups, this study estimates the effects of welfare reform on an important source of human capital acquisition among women at risk for relying on welfare: vocational education and training. The results indicate that welfare reform reduced enrollment in

  18. Characterization of chromosome structures of Falconinae (Falconidae, Falconiformes, Aves) by chromosome painting and delineation of chromosome rearrangements during their differentiation.

    PubMed

    Nishida, Chizuko; Ishijima, Junko; Kosaka, Ayumi; Tanabe, Hideyuki; Habermann, Felix A; Griffin, Darren K; Matsuda, Yoichi

    2008-01-01

    Karyotypes of most bird species are characterized by around 2n = 80 chromosomes, comprising 7-10 pairs of large- and medium-sized macrochromosomes including sex chromosomes and numerous morphologically indistinguishable microchromosomes. The Falconinae of the Falconiformes has a different karyotype from the typical avian karyotype in low chromosome numbers, little size difference between macrochromosomes and a smaller number of microchromosomes. To characterize chromosome structures of Falconinae and to delineate the chromosome rearrangements that occurred in this subfamily, we conducted comparative chromosome painting with chicken chromosomes 1-9 and Z probes and microchromosome-specific probes, and chromosome mapping of the 18S-28S rRNA genes and telomeric (TTAGGG)( n ) sequences for common kestrel (Falco tinnunculus) (2n = 52), peregrine falcon (Falco peregrinus) (2n = 50) and merlin (Falco columbarius) (2n = 40). F. tinnunculus had the highest number of chromosomes and was considered to retain the ancestral karyotype of Falconinae; one and six centric fusions might have occurred in macrochromosomes of F. peregrinus and F. columbarius, respectively. Tandem fusions of microchromosomes to macrochromosomes and between microchromosomes were also frequently observed, and chromosomal locations of the rRNA genes ranged from two to seven pairs of chromosomes. These karyotypic features of Falconinae were relatively different from those of Accipitridae, indicating that the drastic chromosome rearrangements occurred independently in the lineages of Accipitridae and Falconinae. PMID:18293111

  19. Mathematical glimpse on the Y chromosome degeneration

    NASA Astrophysics Data System (ADS)

    Lobo, M. P.

    2006-04-01

    The Y chromosomes are genetically degenerate and do not recombine with their matching partners X. Non-recombination of XY pairs has been pointed out as the key factor for the degeneration of the Y chromosome. The aim here is to show that there is a mathematical asymmetry in sex chromosomes which leads to the degeneration of Y chromosomes even in the absence of XX and XY recombination. A model for sex-chromosome evolution in a stationary regime is proposed. The consequences of their asymmetry are analyzed and lead us to a couple of conclusions. First, Y chromosome degeneration shows up sqrt{2} more often than X chromosome degeneration. Second, if nature prohibits female mortalities from beeing exactly 50%, then Y chromosome degeneration is inevitable.

  20. Genetics Home Reference: Isodicentric chromosome 15 syndrome

    MedlinePLUS

    ... An isodicentric chromosome contains mirror-image segments of genetic material and has two constriction points (centromeres), rather than ... of two extra copies of a segment of genetic material from chromosome 15, attached end-to-end. Typically ...

  1. Genetics Home Reference: Y chromosome infertility

    MedlinePLUS

    ... chromosome infertility is usually caused by deletions of genetic material in regions of the Y chromosome called azoospermia ... AZF regions may affect several genes. The missing genetic material likely prevents production of a number of proteins ...

  2. Detection of amplified or deleted chromosomal regions

    DOEpatents

    Stokke, T.; Pinkel, D.; Gray, J.W.

    1995-12-05

    The present invention relates to in situ hybridization methods for the identification of new chromosomal abnormalities associated with various diseases. In particular, it provides probes which are specific to a region of amplification in chromosome 20. 3 figs.

  3. Chromosomes from testicular preparations of lepidoptera.

    PubMed

    Miller, L D; Miller, S M

    1966-04-22

    Typical elongate, beaded chromosomes have been observed in squash preparations of testicular tissue of the butterfly Speyeria aphrodite (Fabricius), the first demonstration of relatively uncondensed chromosomes in the Lepidoptera. PMID:17815082

  4. NCI Center of Excellence in Chromosome Biology

    Cancer.gov

    Chromosome biology in the 21st century focuses on genome function in the context of the intact eukaryotic cell nucleus. Its goals are a comprehensive understanding of the mechanisms involved in chromosome function, and the correction of aberrations in the

  5. Detection of amplified or deleted chromosomal regions

    DOEpatents

    Stokke, Trond (San Francisco, CA); Pinkel, Daniel (Walnut Creek, CA); Gray, Joe W. (San Francisco, CA)

    1995-01-01

    The present invention relates to in situ hybridization methods for the identification of new chromosomal abnormalities associated with various diseases. In particular, it provides probes which are specific to a region of amplification in chromosome 20.

  6. Detection Of Amplified Or Deleted Chromosomal Regions

    DOEpatents

    Stokke, Trond (San Fransisco, CA), Pinkel, Daniel (Walnut Creek, CA), Gray, Joe W. (San Fransisco, CA)

    1997-05-27

    The present invention relates to in situ hybridization methods for the identification of new chromosomal abnormalities associated with various diseases. In particular, it provides probes which are specific to a region of amplification in chromosome 20.

  7. An Automated System for Chromosome Analysis

    NASA Technical Reports Server (NTRS)

    Castleman, K. R.; Melnyk, J. H.

    1976-01-01

    The design, construction, and testing of a complete system to produce karyotypes and chromosome measurement data from human blood samples, and to provide a basis for statistical analysis of quantitative chromosome measurement data are described.

  8. Chromosomal destabilization during gene amplification.

    PubMed Central

    Ruiz, J C; Wahl, G M

    1990-01-01

    Acentric extrachromosomal elements, such as submicroscopic autonomously replicating circular molecules (episomes) and double minute chromosomes, are common early, and in some cases initial, intermediates of gene amplification in many drug-resistant and tumor cell lines. In order to gain a more complete understanding of the amplification process, we investigated the molecular mechanisms by which such extrachromosomal elements are generated and we traced the fate of these amplification intermediates over time. The model system consists of a Chinese hamster cell line (L46) created by gene transfer in which the initial amplification product was shown previously to be an unstable extrachromosomal element containing an inverted duplication spanning more than 160 kilobases (J. C. Ruiz and G. M. Wahl, Mol. Cell. Biol. 8:4302-4313, 1988). In this study, we show that these molecules were formed by a process involving chromosomal deletion. Fluorescence in situ hybridization was performed at multiple time points on cells with amplified sequences. These studies reveal that the extrachromosomal molecules rapidly integrate into chromosomes, often near or at telomeres, and once integrated, the amplified sequences are themselves unstable. These data provide a molecular and cytogenetic chronology for gene amplification in this model system; an early event involves deletion to generate extrachromosomal elements, and subsequent integration of these elements precipitates a cascade of chromosome instability. Images PMID:2188107

  9. Coordinator's Report: Chromosome 7H

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This report summarizes published research across the world in 2006 that placed additional markers, genes and quantitative trait loci (QTLs) on barley chromosome 7H. Some of the traits located include those affecting agronomic traits, root system size, vernalization, and cold tolerance. Studies conti...

  10. CHROMOSOMAL MULTIPLICITY IN BURKHOLDERIA CEPACIA

    EPA Science Inventory

    We have used CHEF gel electrophoresis to screen preparations of large DNA from different Burkholderia cepacia isolates for the presence of DNA species corresponding to the linearized forms of the three chromosomes of 3.4,2.5, and 0.9 Mb identified in B. cepacia strain 17616. DNA ...

  11. Chromosome analysis guidelines preliminary report.

    PubMed

    Knutsen, T; Bixenman, H A; Lawce, H; Martin, P K

    1991-03-01

    These guidelines have been developed by the Association of Cytogenetic Technologists (ACT) for chromosome analysis. In formulating its recommendations, the task force reviewed guidelines established by several states and regional genetics groups. Draft guidelines prepared by the task force were reviewed by a panel of expert consultants, all of whom are laboratory directors and well known in their respective fields of expertise. The intention of the task force was to reflect procedures that are believed to be generally accepted by cytogenetic laboratories as basic criteria for effective chromosome analysis and that are consistent with existing cytogenetic quality assurance guidelines. It is important to stress that the primary purpose of the task force at this time is to establish guidelines for chromosome analysis. While the present guidelines address issues other than chromosome analysis, they do so incidentally and only in general terms. A more comprehensive discussion of other technical aspects of cytogenetics can be found in the forthcoming second edition of the ACT Cytogenetics Laboratory Manual. It is important to note that these guidelines are not intended to prescribe appropriate analyses for all individual circumstances. That determination is appropriately a matter for the judgment of the laboratories concerned. ACT, its members, and the task force that assisted in preparation of these guidelines make no warranty and assume no liability with respect to the information contained herein. PMID:2009505

  12. Chromosome transfer in mature oocytes.

    PubMed

    Tachibana, Masahito; Sparman, Michelle; Mitalipov, Shoukhrat

    2010-06-01

    In this article, we describe detailed protocols for the isolation and transfer of spindle-chromosomal complexes between mature, metaphase II-arrested oocytes. In brief, the spindle-chromosomal complex is visualized using a polarized microscope and extracted into a membrane-enclosed karyoplast. Chromosomes are then reintroduced into an enucleated recipient egg (cytoplast), derived from another female, by karyoplast-cytoplast membrane fusion. Newly reconstructed oocytes consist of nuclear genetic material from one female and cytoplasmic components, including mitochondria and mitochondrial DNA (mtDNA), from another female. This approach yields developmentally competent oocytes suitable for fertilization and producing embryonic stem cells or healthy offspring. The protocol was initially developed for monkey oocytes but can also be used in other species, including mouse and human oocytes. Potential clinical applications include mitochondrial gene replacement therapy to prevent transmission of mtDNA mutations and treatment of infertility caused by cytoplasmic defects in oocytes. Chromosome transfer between the cohorts of oocytes isolated from two females can be completed within 2 h. PMID:20539289

  13. Vicia faba chromosomal aberration assay.

    PubMed

    Kanaya, N; Gill, B S; Grover, I S; Murin, A; Osiecka, R; Sandhu, S S; Andersson, H C

    1994-10-16

    A collaborative study involving laboratories in six countries was initiated under the sponsorship of the International Programme on Chemical Safety (IPCS) to determine the sensitivity, efficiency and reliability of the Vicia faba root tip meristem chromosomal aberration assay using a standardized protocol. The six laboratories that participated in this study were located in the Slovak Republic, India, Japan, Poland, Sweden and the USA. All laboratories adhered to a standardized protocol for the Vicia faba chromosomal aberration assay. Four coded chemicals, azidoglycerol (AG), N-methyl-N-nitrosourea (MNU), sodium azide (NaN3) and maleic hydrazide (MH) were tested with the Vicia faba chromosomal aberration assay. Of the four chemicals, three (MH, AG and MNU) were found to be clastogenic and gave a concentration related response. However, the results of NaN3 were equivocal which might be explained by the stability of NaN3. The conclusions from this study suggest that the Vicia faba chromosomal aberration bioassay is an efficient and reliable short-term bioassay for the rapid screening of chemicals for clastogenicity. PMID:7523894

  14. [Ring (20) chromosome epileptic syndrome].

    PubMed

    Hirose, Genjiro

    2015-05-01

    Ring (20) chromosome epilepsy syndrome is characterized by highly refractory epilepsy that is often associated with non-pathognomonic, electroencephalographic (EEG) changes. Seizures typically begin during the stage of childhood around the age of 6 years. Nonconvulsive status epilepticus (NCSE) is the most common seizure types and is distinguished by a long-lasting, confusional state that is often associated with EEG patterns in the form of prolonged, high-voltage slow waves with occasional spike/sharp components. Patients with this syndrome suffer from intractable seizures with cognitive decline and frequent epileptic episodes. Accompanying features of this rare disorder, such as superficial minor dysmorphic abnormalities if any, mental retardation and behavioral changes are quite variable. Because of the variability in clinical presentation, in particular the lack of clear dysmorphic features, the clinical diagnosis of this disorder can be delayed before being diagnosed genetically. Most patients with this syndrome have chromosomal changes in the form of a mosaic. High levels of mosaicism correlate well with a lower age of onset and severe cognitive impairment. Here, we emphasize the importance of early G-banding chromosomal analysis when patients present with unexplainable severe seizures and repetitive NCSE, even in the absence of any dysmorphic features suggestive of a chromosomal disorder. PMID:25957205

  15. The XXXXY Sex Chromosome Abnormality

    PubMed Central

    Barr, M. L.; Carr, D. H.; Pozsonyi, J.; Wilson, R. A.; Dunn, H. G.; Jacobson, T. S.; Miller, J. R.; Chown, B.

    1962-01-01

    The most common sex chromosome complex in sex chromatin-positive males with Klinefelter's syndrome is XXY. When the complex is XXYY or XXXY, the clinical findings do not seem to differ materially from those seen in XXY subjects, although more patients with these intersexual chromosome complements need to be studied to establish possible phenotypical expressions of the chromosomal variants. Two male children with an XXXXY sex chromosome abnormality are described. The data obtained from the study of these cases and five others described in the literature suggest that the XXXXY patient is likely to have congenital defects not usually seen in the common form of the Klinefelter syndrome. These include a triad of (1) skeletal anomalies (including radioulnar synostosis), (2) hypogenitalism (hypoplasia of penis and scrotum, incomplete descent of testes and defective prepubertal development of seminiferous tubules), and (3) greater risk of severe mental deficiency. That the conclusions are based on data from a small number of patients is emphasized, together with the need for a cytogenetic survey of a large control or unselected population. ImagesFig. 1Fig. 2Fig. 3Fig. 4Fig. 5Fig. 6Fig. 7Fig. 8Fig. 9Fig. 10 PMID:13969480

  16. Chromosome synteny in cucumis species

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cucumber, Cucumis sativus L. (2n = 2x = 14) and melon, C. melo L. (2n = 2x = 24) are two important vegetable species in the genus Cucumis (family Cucurbitaceae). Two inter-fertile botanical varieties with 14 chromosomes, the cultivated C. sativus var. sativus L. and the wild C. sativus var. hardwick...

  17. Interpreting chromosomal abnormalities using Prolog.

    PubMed

    Cooper, G; Friedman, J M

    1990-04-01

    This paper describes an expert system for interpreting the standard notation used to represent human chromosomal abnormalities, namely, the International System for Human Cytogenetic Nomenclature. Written in Prolog, this program is very powerful, easy to maintain, and portable. The system can be used as a front end to any database that employs cytogenetic notation, such as a patient registry. PMID:2185921

  18. Highway Maintenance Equipment Operator. Specialized Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes 18 units of instruction covering the large equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance objectives,

  19. Highway Maintenance Equipment Operator. Miscellaneous Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes six units of instruction covering the small, specialized equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance

  20. Getting Equipped and Staying Equipped, Part 2: Finding the Funds.

    ERIC Educational Resources Information Center

    Jordahl, Gregory; Orwig, Ann

    1995-01-01

    Suggests how school libraries can fund computer equipment; gain assistance from high-tech businesses; develop business partnerships and foundations; lease equipment; accept equipment donations; fund raise; build money into the budget; and communicate school needs with budget voters. Sidebars include leasing advice; resources for parent-teacher