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1

Simultaneous double coronary thrombosis in a 47-year-old male patient with acute myocardial infarction  

PubMed Central

Patient: Male, 47 Final Diagnosis: Acute myocardial infarction Symptoms: Chest pain Medication: — Clinical Procedure: — Specialty: Cardiology Objective: Unusual clinical course Background: Double myocardial infarction involving two culprit major vessels is a rarely reported presentation with high incidence of mortality. Case Report: In this study, we report 47-year-old male patient who had an attack of chest pain associated with ST-segment elevation in the antero-lateral leads. Pharmaco-invasive reperfusion approach was adopted with full dose tissue plasminogen activator, followed by transferring the patient to a specialized heart center for Percutaneous Coronary Intervention (PCI). Coronary angiography showed a fresh thrombus totally occluding Left Anterior Descending (LAD) and another thrombus causing distal total occlusion of a dominant Right Coronary Artery (RCA). Two Bare metal stents were placed in both lesions with Thrombolysis in Myocardial Infarction (TIMI) 3 flow post dilatation, but the patient, unfortunately, went into Ventricular Fibrillation (VF) followed by asystole and died 35 minutes later. Conclusions: Acute double vessel coronary artery thrombosis is a serious event that requires prompt diagnosis and management to prevent its complications.

Ahmed, Mahmoud; Abdul, Arabi

2013-01-01

2

Low-tech rehabilitation and management of a 64 year old male patient with acute idiopathic onset of costochondritis  

PubMed Central

Objective This study was conducted to discuss the treatment and management of a patient presenting with acute idiopathic costochondritis. Case 64 year old male patient presenting with acute anterior chest pain of one week duration. Treatment High-velocity low-amplitude thrust manipulation was used to the zygapophyseal joints of the thoracic spine, costotransverse, and costochondral joints involved. Acupuncture, ischemic compression, cross fibre friction massage techniques, and cryotherapy were utilized on the local area of pain. Specific exercise prescription (low tech rehabilitation) was also utilized. Improvement of pain reported on the Visual Analog Scale was noted with a complete resolution of the condition at the conclusion of treatment. No recurrences were reported on an eleven month follow up of the patient. Conclusion Conservative management, including manipulation and exercise prescription, may be beneficial in the treatment of benign costochondritis.

Hudes, Karen

2008-01-01

3

Delayed diagnosis of Kearns-Sayre syndrome in a 38-year-old male patient: a case report.  

PubMed

Kearns-Sayre syndrome is a rare disorder caused by mitochondrial deoxyribonucleic acid deletion. It is characterized by a triad of progressive external ophthalmoplegia, initial symptoms that develop before the age of 20 years, and pigmentary retinopathy. Multisystem involvement is frequently associated with those features. Ragged red fibers can be identified during histopathologic examination and confirmed by electron microscopy. In this article, the case of a 38-year-old man with Kearns-Sayre syndrome in whom diagnosis was delayed despite abundant clinical evidence is presented. A brief review of clinical and laboratory findings in patients with that disorder is also provided. PMID:18205082

Yerdelen, Deniz; Koc, Filiz; Koc, Zafer

2008-02-01

4

Mumps virus encephalomyelitis in a 19-year old male patient with an undefined severe combined immunodeficiency post-haematopoietic bone marrow transplantation: a rare fatal complication.  

PubMed

We describe a rare case of fatal mumps encephalomyelitis occurring in 19-year old male following matched unrelated donor peripheral blood haematopoietic stem cell transplantation (HSCT). The indication for HSCT was for an undefined form of severe combined immunodeficiency (SCID). Molecular typing of the mumps viral RNA isolated from neural tissue indicated that the infection was acquired at the time of a mumps outbreak in England and Wales that occurred between 2004 and 2006. This case highlights the importance of considering mumps in the differential diagnosis of central nervous system infection in highly immunosuppressed patients. PMID:23485346

Eyre, Toby A; Pelosi, Emanuela; McQuaid, Stephen; Richardson, Deborah; Newman, Joan; Hill, Kate; Veys, Paul; Davies, Graham; Orchard, Kim H

2013-02-26

5

An 11-Year-Old Male with Refractory Osteomyelitis  

PubMed Central

We present a case of empirical treatment failure for chronic osteomyelitis in a previously healthy 11-year-old male involving the distal phalanx of the right first digit. After initial debridement, empiric antibiotics were started for presumed Staphylococcus aureus infection. Operative bacterial cultures yielded no growth. Despite three weeks of antistaphylococcal antibiotics the patient's symptoms worsened and the destruction of bone progressed. A repeat plain X-ray revealed a new lesion in the proximal phalanx of the right second digit. The recognition of multifocal osteomyelitis led to reexamination of bone tissue specimens using special stains which demonstrated rare broad-based budding yeast. Fungal cultures eventually grew Blastomyces dermatitidis. Treatment with amphotericin B led to rapid clinical improvement. This case illustrates that clinicians must remain vigilant for warning signs that empiric treatment may be failing for presumptive Staphylococcus aureus, provoking reconsideration of the differential diagnosis and an intensification of efforts to evaluate for alternative etiologies.

Mauriello, Clifford T.; Raustol, Ole A.; Aguiar, Maria A.; Cunnion, Kenji M.

2012-01-01

6

Atypical cause of stroke in a 27 year old male  

PubMed Central

Summary Background: Central nervous system (CNS) Tuberculosis (TB) meningitis is a progressive disease that can present in many forms. CNS TB is encountered frequently in areas of high prevalence of tuberculosis and dissemination is common, but TB meningitis is a disease that has a relatively low prevalence in North America. Case Report: 27 year-old African American male presented with complaints of headache, altered mental status (AMS), and seizure activity. He was found to have fever, encephalopathy, and leukocytosis. Work up of his AMS revealed cerebral spinal fluid (CSF) consistent with acute lymphocytic meningitis and magnetic resonance imaging (MRI) revealed right basilar meningeal enhancement with acute right basal ganglia infarction. Given the characteristic CSF and MRI finding for Tuberculosis (TB) a computed tomography (CT) of the chest was performed which revealed right upper lobe nodules with central cavitations. Biopsy results revealed Tuberculosis. The patient showed significant improvement once empiric tuberculosis therapy was begun. Conclusions: CNS TB is a treatable disease that will be fatal if not recognized early. It is imperative to be aware of the key clinical features of TB meningitis, and maintain a high level of suspicion when dealing with CNS infection if the cause is unknown.

Youngblood, Laura B.; Dooley, Jennifer Whitley

2012-01-01

7

[Bromo-Dragonfly poisoning of 18-year-old male].  

PubMed

Bromo-Dragonfly (BDF) is a designer drug chemically related to LSD and amphetamine. The first registration in Denmark was in October 2007. In the present case an 18-year-old man ingested about 2 ml BDF and developed acute psychosis. At the hospital the patient displayed, hyperpyrexia, tachycardia, tachypnea and hypertension. Because of severe hallucinations and agitation the patient was detained at the hospital and received symptomatic treatment with large doses of benzodiazepines. Four days after hospitalization, the patient discharged himself without significant symptoms or paraclinical findings. PMID:20470659

Nielsen, Visti Torbjørn; Høgberg, Lotte C G; Behrens, Jens Kristian

2010-05-10

8

A 52-year-old male with visual changes.  

PubMed

A 52 year-old male with a history of Cushing's Disease at age 18 and bilateral adrenalectomy at age 23 presented with visual changes. An MRI scan showed a pituitary macroadenoma (Nelson's syndrome). Other than the development of diabetes mellitus at age 32, his disease was stable until presentation. Serum studies show markedly elevated ACTH levels, but he had no hyperpigmentation. The tumor was removed by endoscopic surgery. Microscopic examination showed a pituitary adenoma with strong immunostaining for ACTH. In addition, the tumor cells showed Crooke's hyaline change and stained strongly for cytokeratin (Crooke's Cell Adenoma). Normal pituitary was not present. Crooke's cell adenomas are extremely rare and have not been previously reported in Nelson's Syndrome. PMID:22697384

Atkinson, David M; Hamilton, Ronald L

2012-07-01

9

81 year-old male with confusion and weakness.  

PubMed

Glioblastoma, the most common primary brain tumor, is a highly infiltrative, malignant astrocytic neoplasm that demonstrates a wide spectrum of morphologic heterogeneity. Cases with a primitive neuroectodermal tumor (PNET)-like component are rare, but are being increasingly recognized and studied. The primitive component typically shows immunohistochemical features that are indicative of potential for divergent differentiation along glial and neuronal pathways; when present, the entire neuraxis may be at risk for involvement, portending a particularly poor prognosis. Recently, data from the largest case series studying malignant gliomas with a PNET-like component suggest that the primitive component likely arises from the malignant glial component. This report presents an example of glioblastoma with a prominent primitive neuroectodermal-like component in an 81 year-old male who, during the course of concurrent chemotherapy and radiation therapy, died five weeks following initial diagnosis. PMID:20626749

Le, Brian H; Sandusky, Matthew

2010-07-01

10

Thyroid involvement with Langerhans cell histiocytosis in a 3-year-old male.  

PubMed

We report on the thyroid involvement with Langerhans cell histiocytosis (LCH) in a 3-year-old male. The patient presented with goiter and primary hypothyroidism. His goiter caused life-threatening airway obstruction. He developed locally invasive disease 4 years after his response to LCH therapy. LCH should be suspected as a cause of goiter and thyroidectomy is recommended. PMID:16944476

Burnett, Aaron; Carney, David; Mukhopadhyay, Sanjay; Scalzetti, Ernest M; Leino, Daniel; Souid, Abdul-Kader

2008-03-01

11

Recurrent cardiac myxoma in a 25 year old male: a DNA study  

PubMed Central

We present a 25 year old Caucasian male patient with multiple recurrences of cardiac myxomas after surgical removal of the original tumor. His mother was operated on for right ventricular myxoma. The genetic analyses disclosed an aneuploid DNA content by flow cytometry analysis. The familial form of the cardiac myxomas must be distinguished from Carney complex syndrome. A long- term echocardiographic follow up is recommended to patients and their first degree relatives with cardiac myxomas.

2013-01-01

12

Pathology Case Study: Bladder Mass in a 73-Year-Old Male  

NSDL National Science Digital Library

This case study, from the University of Pittsburgh School of Medicine's Department of Pathology, presents information about a 73-year-old male patient. According to the patient's history, he has a "history of invasive papillary transitional cell carcinoma with excessive muscular invasion and angiolymphatic invasion." Both gross and microscopic images of the prostate, bladder, pelvic lymph nodes, and the right and left pelvic ureter are provided in this case. Using these images and the provided patient history, students can test their knowledge of pathology and compare their diagnostic findings with the official findings in the "Final Diagnosis" section.

Hakam, Ardeshir

2007-07-26

13

Multiple bilateral traumatic pulmonary pseuodocysts in a 53 year-old male diagnosed retrospectively.  

PubMed

Traumatic pulmonary pseudocyst (TPPC) is a rare complication, which might be encountered after thoracic trauma. It is most often (75-100%) seen in children and young adults. A 53 year-old male presented with multiple bilateral pulmonary cysts after a motor vehicle accident. We evaluated the patient for abscess, tuberculosis, and Wegener's granulomatosis with negative results. Follow up chest X-rays showed spontaneous resolutions of pseudocysts with replacement with pneumatocelae. In patients with recent chest trauma, TPPC should be kept in mind to prevent unnecessary invasive tests. PMID:20695363

Rahimi-Rad, Mohammad Hossein; Mohammadi, Afshin

14

Use of personalized decision analysis in decision making for Palliative vs. surgical management of the oldest-old patients with localized skin cancer in a culturally sensitive environment: a case study of a 96-year-old male Taiwanese patient.  

PubMed

Clinical management of older cancer patients is challenging, especially for those in the oldest-old age group. In the Chinese culture, the preference toward noninvasive care for patients in this age group may create a difficult situation for clinicians when the cancer is potentially curable. Palliative care may not always be the obvious choice, especially if patients suffer from quality-of-life impairment because of symptoms related to progression of the untreated cancer. Balancing between higher rates of toxicities and potential gains in quality of life from anticancer therapies among the oldest old presents a real challenge in clinical practice. Decision analysis is an analytical tool that has a long history of successful application in clinical decision making. In this case study of a 96-year-old male with localized skin cancer, we demonstrate that personalized decision analysis can be a helpful tool to assist decision making in the clinical management of cancer patients in the oldest-old age group, especially in situations in which the evidence-based literature provides little guidance. This was achieved by providing information to help the key decision makers to better understand the risk-benefit trade offs and make an informed decision. We found that the option of surgical management was associated with higher expected quality-adjusted life years (0.894) than best supportive care (0.853). Based on this finding and various scenarios explored in sensitivity analyses, the family members recommended surgery for the patient. The patient recovered well from surgery and there is no evidence of recurrence to date. PMID:22917709

Chien, Chun-Ru; Shih, Ya-Chen Tina

2012-08-20

15

Multiple arterial emboli secondary to left ventricular thrombus in a 35-year-old obese male.  

PubMed

The very unusual case of a 35-year-old obese male patient with a left ventricular (LV) thrombus secondary to a silent myocardial infarction and resultant shower emboli to multiple arterial sites is described. His presentation with acute limb ischemia led to arterial imaging and the identification of the underlying cardiac pathology in addition to splenic and bilateral renal infarcts. He was also found to suffer from previously undiagnosed hypertension. He underwent femoral embolectomy and multiple arterial revascularization attempts but required bilateral above knee amputations and a prolonged intensive care unit stay. This rare and extreme example of a LV thrombus in a young male emphasizes the potential sequellae of the condition. Furthermore, with the increasing incidence of obesity this case demonstrates the importance of considering undiagnosed cardiovascular risk factors when assessing obese patients. PMID:21264185

Chetwood, Andrew; Sanders, Alison; Saweirs, Martin; Thapar, Ankur; Davies, Alun H

2010-10-01

16

Ninety-seven Years Old Hispanic Male With Mantle Cell Lymphoma  

PubMed Central

Treating geriatric patients can be difficult. Patients often present with subtle or atypical symptoms, and end-of-life care is rarely neatly packaged. We present a case of a 97 years old Hispanic male with multiple medical problems who was diagnosed with mantle cell lymphoma after thoracentesis from what was thought to be a para-pneumonic effusion. An oncology evaluation determined that he was not a candidate for aggressive treatment. There is no evidence of curative treatment for mantle cell lymphoma. To complicate the decision making process further, the patient’s primary caregiver requested specifically that the health care team withholds the diagnosis from the patient. We discuss the inherent difficulties associated with end-of-life care. Keywords Geriatrics; End-of-life care; Mantle cell lymphoma; Hispanic

Thompson, Beth; Gonzalez, Maria Rosaida

2010-01-01

17

Pathology Case Study: 15 Year Old Male With a Left Testicular Mass  

NSDL National Science Digital Library

This genitourinary pathology case study, provided by the University of Pittsburgh Department of Pathology, is an excellent resource for students and instructors in the health science fields. A 15-year-old male with a left testicular mass is the focus of this case. The patientâÂÂs history, gross description, and microscopic description of test results are provided to aid readers in understanding the patientâÂÂs diagnosis. The official final diagnosis is accompanied by a discussion of the contributing doctorâÂÂs findings and a list of references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose patientâÂÂs conditions.

Bastacky, Sheldon; Molina, J. T.; Ionescu, Diana

2009-02-11

18

Primary lymphedema tarda in an 88-year-old African-American male.  

PubMed Central

Primary lymphedema tarda is considered to be a congenital disease with delayed manifestations. We report a case of isolated lymphedema of the left upper extremity in an 88-year-old African-American male. The diagnosis of lymphedema was confirmed by lymphoscintigraphy, and appropriate diagnostic studies were done to rule out other known causes of lymphedema. Lymphoscintigraphic findings were consistent with idiopathic primary lymphedema. During the course of investigations, the patient was found to have adenocarcinoma in situ of the sigmoid colon with no evidence of metastatic spread. Based on the available data, we were unable to establish a causative relationship between colonic carcinoma and lymphedema in our patient. Therefore, this case can best be described as a case of Idiopathic primary lymphedema tarda. We emphasize the use of histopathologic examination in the diagnostic algorithm to rule out underlying malignant process only in patients with radionuclide findings suggestive of secondary lymphedema with no obvious etiology. Images Figure 1 Figure 2

Aslam, Ahmed Faraz; Aslam, Ahmad Kamal; Qamar, Muhammad Umair R.; Levey, Robert

2005-01-01

19

[67-year-old patient with speech disorder and dysphagia].  

PubMed

A 67-year-old man who had been heart transplanted ten years before was admitted to our hospital because of diarrhea. During his stay he developed a severe lingual and facial angioedema. After excluding hereditary angioedema caused by a deficiency in functional C1 esterase inhibitor we focused on adverse effects of his drugs. The medication was composed of Aspirin, Enalapril, Diltiazem, Everolimus, Mycophenolate Mofetil, Bisoprolol, Pravastatin, Esomeprazol and Allopurinol. The angioedema disappeared with anti-allergic treatment. The administration of the suspected trigger enalapril was stopped. However weeks later the patient was admitted again with angioedema. Due to missing urticaria Aspirin was unlikely the causer. The only new drug the patient had been medicated with was Everolimus for 30 days. We assumed a link between the angioedema and Everolimus. Consequently we changed the immunosuppressive regime. After stopping Everolimus no angioedema occurred. Conclusion: Everolimus is a potential trigger of angioedema. PMID:19006046

Er, F; Nia, A M; Erdmann, E

2008-11-12

20

Perinephric Haematoma Causing Refractory Hypertension in a 17-Year-Old Male  

PubMed Central

New-onset arterial hypertension is a well-recognised complication of kidney trauma. Cases have been described in young healthy athletes with hypertension arising years after sports-related trauma. The pathophysiology of this disease is thought to arise from intrarenal arterial stenosis resulting from rapid deceleration during the initial injury. This leads to arterial obstruction and ischaemia with increased secretion of renin, eventually leading to elevated blood pressure. Though hypertension in these cases is generally gradual in onset and long-standing, it can also rise acutely, leading to malignant hypertension. We present the case of a 17-year-old male who presented with refractory hypertension following blunt trauma to his left kidney during a recent sporting injury. This is followed by a discussion of the relevant literature in this area to date, highlighting the key challenges involved in the management of these patients.

Kelly, Y.P.; Eustace, J.A.

2012-01-01

21

Transcatheter Closure of Secundum Atrial Septal Defect in Patients Over 60 Years Old  

PubMed Central

Background and Objectives Atrial septal defect (ASD) is the one of most common congenital heart diseases detected in adults. Along with remarkable development of device technology, the first treatment strategy of secundum ASD has been transcatheter closure in feasible cases. However, there are only a few publications regarding the results of transcatheter closure of ASD in elderly patients, especially those over 60 years of age. We report our results of transcatheter closure of ASD in patients over 60 years old. Subjects and Methods Between May 2006 and December 2011, 31 patients over 60 years old (25 female and 6 male; mean 66.7±5.25 years old, range 61-78 years old) were referred to our center. Results A total of 23 patients underwent therapeutic catheterization to close secundum ASD, and the closure was successful in 22 patients (95.7%). All patients who underwent the procedure survived except for one patient who expired because of left ventricular dysfunction. A small residual shunt was observed in two (9%) of 21 patients before discharge but disappeared at follow-up. All patients eventually had complete closure. There were five patients who had coronary problems. One patient underwent percutaneous coronary intervention using a stent at the same time as transcatheter closure of ASD. Atrial arrhythmias were detected in 6 of 23 patients (26.1%) before the procedure. One patient was successfully treated by radiofrequency ablation before the procedure. No patients displayed new onset arrhythmia during the follow-up period. Follow-up echocardiographic evaluation showed a significantly improved right ventricular geometry. Conclusion We conclude that transcatheter closure of ASD is a safe and an effective treatment method for patients over 60 years old if the procedure is performed under a thorough evaluation of comorbidities and risk factors.

Woo, Saet Byul; Kim, Seong-Ho; Kim, Soo-Jin; Lee, Sang-Yun; Baek, Jae-Sook; Shim, Woo-Sup

2013-01-01

22

Successful Removal of a Penile Constriction Ring in a 14-Year-Old Male  

PubMed Central

Penile strangulation is a rarely described medical emergency, especially in the adolescent population. This case demonstrates the successful removal of a constricting metal ring from the penis of a 14-year-old male with a diamond blade equipped orthopedic oscillating saw while under ketamine anesthesia in the emergency department.

Suttle, Timothy K.; Palmer, Blake; Heinlen, Jonathan E.; Roth, Christopher C.; Reiner, William G.; Frimberger, Dominic

2009-01-01

23

Hermeneutical Portrait of Today’s 18–22 Year Old Young Adult Male  

Microsoft Academic Search

This article’s objective is to help uncover today’s 18–22 year old young adult male in his modern day milieu in order to paint\\u000a a hermeneutical portrait of his maleness and masculinity. It will attempt to do so utilizing two main categories: (1) psycho-social\\u000a development and (2) socio-cultural types and archetypes. Psycho-social development refers to the meaning and telos of the young

Robert J. Parmach

2010-01-01

24

A 26-Year-Old Male with Mesothelioma Due to Asbestos Exposure  

PubMed Central

Mesothelioma is a malignancy with poor prognosis, with an average 5-year survival rate being less than 9%. This type of cancer is almost exclusively caused by exposure to asbestos. A long exposure can cause mesothelioma and so can short ones, as each exposure is cumulative. We report a case of a 26-year-old male who was exposed to asbestos during his primary school years from the age of 6 to 12. Although the tumor mainly affects older men who in their youth were occupationally exposed to asbestos, malignant mesothelioma can also occur in young adults. A medical history was carefully taken and asbestos exposure was immediately mentioned by the patient. We conducted biopsy on the right supraclavicular lymph node. The patient was not a candidate for surgery, and chemotherapy treatment was initiated. While patient's chemotherapy is still ongoing, no other similar cases of students or teachers have been traced up to date from his school. The school building was demolished in January 2009.

Zarogoulidis, P.; Orfanidis, M.; Constadinidis, T. C.; Eleutheriadou, E.; Kontakiotis, T.; Kerenidi, T.; Sakkas, L.; Courcoutsakis, N.; Zarogoulidis, K.

2011-01-01

25

Sudden unexpected death of a 17-year-old male infected with the influenza virus  

Microsoft Academic Search

We report a case of sudden unexpected death in a 17-year-old male student showing similar clinical background and pathological findings to Reye's syndrome. He was found following cardio-pulmonary arrest in his bed, and was immediately transferred to a hospital. However, resuscitation was not successful. He had a history of high fever of 38.3°C, general malaise, myalgia, and gastrointestinal discomfort for

Naoki Nishida; Takashi Chiba; Maki Ohtani; Naofumi Yoshioka

2005-01-01

26

Life-threatening aortic dissection with cardiac tamponade in a healthy 15-year-old male.  

PubMed

We present a case of aortic dissection with shock due to cardiac tamponade in a previously healthy 15-year-old male. The diagnosis was suspected and confirmed by transthoracic echocardiography before transfer to the cardiothoracic unit for successful surgical intervention. Because it is a rare life-threatening condition with a high mortality rate in the pediatric population, a very high index of suspicion is required to reach the clinical diagnosis in a timely manner and institute appropriate surgical management. PMID:16944331

Thattakkat, K; Zbaeda, M

2006-08-30

27

Beneficial effects of chrysin and benzoflavone on virility in 2-year-old male rats.  

PubMed

This work describes the potential usefulness of bioflavonoids for countering the deleterious effects of aging on male sexuality in 2-year-old rats. A flavone chrysin from Passiflora caerulea Linn. and a benzoflavone moiety (BZF) recently isolated from Passiflora incarnata Linn. were administered to 2-year-old male rats for a period of 30 days. After cessation of these treatments, there was a significant improvement in overall sexual functions in the rats given bioflavonoids, compared with control rats. The rats receiving chrysin (1 mg/kg) and BZF (10 mg/kg) exhibited increased libido when they were allowed to interact with nonestrous female rats. Additionally, both treated groups had increased sperm count, greater fertilization potential, and greater litter size when they were allowed to interact with proven proestrous female rats of a similar strain. BZF was more potent than chrysin as an antiaromatase agent and exhibited better effects on the sexual system of the 2-year-old male rats. Plant flavonoids have great potential for clinical and therapeutic applications against the physiological and biochemical effects of aging. PMID:12511112

Dhawan, Kamaldeep; Kumar, Suresh; Sharma, Anupam

2002-01-01

28

Lung mass in a 28-year-old male: a case report of a rare tumor.  

PubMed

A twenty eight-year-old male presented with a two week history of dyspnea, cough, hemoptysis, chest pain, and fever 38-39°C. He also complained of loss of appetite, general weakness and left leg pain for two months preceding admission. He was referred with suspicion of lung tumor to our institution. Chest X-ray showed almost total atelectasis of the right lung with compensatory overinflation of the contralateral lung. Using computed tomography (CT), a lesion of diameter of 19.3 x 14.1 x 19.1 cm in the right lung, pleuritis, Th3 osteolysis, and compensatory overinflation of the left lung was seen. Bronchoscopy revealed a total obstruction of the right main bronchus due to submucosal infiltration and compression of the right main bronchus with negative histology of bronchial biopsy specimens. Transthoracic fine needle aspiration revealed celullae suspectae probabiliter neoplasmaticae suggesting tumor fusocellularis. USG of the abdomen revealed liver with numerous heterogeneous, solid areas hypo- and hyperechogenic, some of them with features of liquid or the disintegration up to diameter of 74 mm. Subsequent fine needle aspirations of the thorax and liver revealed fibrolamellar hepatocarcinoma and carcinoma adenoides of the lung. Patient underwent chemotherapy with 5-FU/DDP/VCR with no response. This report presents a case of a rare lung metastasis from FL-HCC. PMID:21147631

Mroz, Robert M; Korniluk, M; Swidzinska, E; Dzieciol, J; Czaban, J; Panek, B; Chyczewska, E

2010-11-01

29

[Sudden visual loss in a 7-year old patient].  

PubMed

A 7-year-old boy presented to us with a sudden bilateral decrease in visual acuity. At the age of 4 months bilateral congenital glaucoma had been diagnosed and trabeculotomy performed. Eye pressure and fundus were monitored regularly. Both magnetic resonance imaging and computed tomography revealed a giant supraclinoid aneurysm originating in the right internal carotid artery. After comprehensive examinations endovascular balloon occlusion of the internal carotid artery was performed in conjunction with extracranial-intracranial bypass to augment the insufficient circulation. PMID:18779968

Brandner, M; Lindner, S; Langmann, A

2009-03-01

30

Reference values of thirty-one frequently used laboratory markers for 75-year-old males and females  

PubMed Central

Background We have previously reported reference values for common clinical chemistry tests in healthy 70-year-old males and females. We have now repeated this study 5 years later to establish reference values also at the age of 75. It is important to have adequate reference values for elderly patients as biological markers may change over time, and adequate reference values are essential for correct clinical decisions. Methods We have investigated 31 frequently used laboratory markers in 75-year-old males (n = 354) and females (n = 373) without diabetes. The 2.5 and 97.5 percentiles for these markers were calculated according to the recommendations of the International Federation of Clinical Chemistry. Results Reference values are reported for 75-year-old males and females for 31 frequently used laboratory markers. Conclusion There were minor differences between reference intervals calculated with and without individuals with cardiovascular diseases. Several of the reference intervals differed from Scandinavian reference intervals based on younger individuals (Nordic Reference Interval Project).

Ryden, Ingvar; Lind, Lars

2012-01-01

31

Heel pain due to psoriatic arthritis in a 50 year old recreational male athlete: case report  

PubMed Central

Heel pain is a common presentation in a sports injury practice, with a list of common differentials including achilles tendinopathy and retrocalcaneal bursitis. However, seronegative arthritis can also cause enthesopathies that produce heel pain and should be considered in a differential diagnosis list. In this case, a 50 year old recreationally active male presented with non-traumatic insidious heel pain and without history of any skin conditions or any other symptoms of seronegative spondyloarthritis. Clinical suspicion led to laboratory testing and radiographs/bone scan which yielded the diagnosis of psoriatic arthritis.

Yedon, Dominique Forand; Howitt, Scott

2011-01-01

32

29 year-old male with seizure and syncope. Intracerebral Langerhans cell histiocytosis.  

PubMed

Langerhans cell histiocytosis (LCH), previously referred to as histiocytosis X, is a dendritic cell histiocytic tumor that demonstrates a variable spectrum of organ involvement. Clinical syndromes within this entity include eosinophilic granuloma, Hand-Schuller-Christian disease, Abt-Letterer-Siwe Disease, and Hashimoto-Pritzker disease. Currently, it is classified on the basis of extent, such as unifocal, multifocal, or disseminated disease. LCH typically occurs in childhood and adolescence as solitary osteolytic lesions. When involving the central nervous system, it is usually either a result of extra-axial extension from skull vault epicenters, or is restricted to the hypothalamic-pituitary axis. Discrete intraparenchymal, intra-axial CNS lesions are rare. This report presents a case of an intra-axial LCH in a 29 year-old male who, following this diagnosis, was found to have multiple pulmonary lesions on imaging, attributed to the same disease process. PMID:23587144

Le, Brian H; Truex, Raymond C

2013-05-01

33

Dissociative fugue symptoms in a 28-year-old male Nigerian medical student: a case report  

PubMed Central

Introduction Dissociative fugue is a psychiatric disorder characterized by amnesia coupled with sudden unexpected travel away from the individual’s usual surroundings and denial of all memory of his or her whereabouts during the period of wandering. Dissociative fugue is a rare disorder that is infrequently reported. Before now, no case of it had been reported in a medical student. Case presentation This article focuses on the report of a case of dissociative fugue symptoms in a 28-year-old male Nigerian medical student. Conclusion The observation in this case report brings to the fore that dissociative fugue is often related to stressful life events and can comorbid with a depressive disorder.

2013-01-01

34

Four-year-olds' beliefs about how others regard males and females.  

PubMed

Children's awareness of how others evaluate their gender could influence their behaviours and well-being, yet little is known about when this awareness develops and what influences its emergence. The current study investigated culturally diverse 4-year-olds' (N = 240) public regard for gender groups and whether exposure to factors that convey status and highlight gender influenced it. Children were asked whether most people thought (i) girls or boys, and (ii) women or men, were better. Overall, children thought others more positively evaluated their own gender. However more TV exposure and, among girls only, more traditional parental division of housework predicted children stating that others thought boys were better, suggesting more awareness of greater male status. Children's public regard was distinct from their personal attitudes. PMID:23331111

Halim, May Ling; Ruble, Diane N; Tamis-LeMonda, Catherine S

2012-09-19

35

Pathology Case Study: 21 Year Old Male With Back Pain and Wobbly Gait  

NSDL National Science Digital Library

This neuropathology case study, provided by the University of Pittsburgh Department of Pathology, is an excellent learning tool for students and instructors in the health science fields. In this case, a 21-year-old man presents with a three-week history of thoracic myelopathy, decreased sensation, and a wobbly gait. Visitors are shown MRI images of the patientâÂÂs spine, along with microscopic images and a gross description of the condition. The official diagnosis found in the âÂÂFinal Diagnosisâ section is accompanied by a discussion of the contributing doctorâÂÂs findings and a list of references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose patientâÂÂs conditions

Krisky, David; Molina, J. T.; Wiley, Clayton

2009-02-16

36

[The operated case of 89 year-old patient with pleomorphic carcinoma of the lung].  

PubMed

A-89-year-old male patient who complained dry cough was detected lung mass of 3 cm size in diameter at the right upper lobe by CT. FDG-PET seemed to show hilar and mediastinum lymph nodes metastasis. After three weeks, the mass showed rapid growth with 5 cm diameter in size at CT. Therefore the original tumor was supposed to be undifferentiated carcinoma, above all, pleomorphic carcinoma. He had been done pulmonary resection after short period. The right upper lobectomy with combined resection of the partial middle lobe was performed. Hilar and mediastinum lymph nodes dissection was added. In pathological examination, the tumor was proved pleomorphic carcinoma, however, no lymph node metastasis was recognized. He did not refer any complications and discharged back home at the post-operative 11th day. Pleomorphic carcinoma of the lung is known to be difficult to obtain definite diagnosis in early stage because of rapid growth. Therefore many cases are detected in advanced stage. In addition, chemotherapy is generally not effective, so only operative resection seems to be useful. Our patient was 89-year-old, he tolerated the operation and was alive with no trouble during 6 months after resection. When complete resection seems to be possible, operation should be regarded as an initial treatment. PMID:23367857

Matsubara, Yutaka; Tateishi, Masahiro; Okuyama, Toshirou; Edagawa, Ai; Higashi, Takahiro; Ishii, Hirokuni; Nagata, Shigeyuki; Hashimoto, Kenkichi; Uchiyama, Hideaki; Eguchi, Daihiko; Kawanaka, Hirofumi; Korenaga, Daisuke; Takenaka, Kenji

2012-09-01

37

GH overexpression decreases spermatic parameters and reproductive success in two-years-old transgenic zebrafish males.  

PubMed

Growth hormone (GH) transgenesis has been postulated as a biotechnological tool for improving growth performance in fish aquaculture. However, GH is implied in several other physiological processes, and transgenesis-induced GH excess could lead to unpredictable collateral effects, especially on reproductive traits. Here, we have used two-years-old transgenic zebrafish males to evaluate the effects of GH-transgenesis on spermatic parameters and reproductive success. Transgenic spermatozoa were analyzed in terms of motility, motility period, membrane integrity, mitochondrial functionality, DNA integrity, fertility and hatching rate. We have also performed histological analyses in gonad, in order to verify the presence of characteristic cell types from mature testes. The results obtained have shown that, even in transgenic testes present in all cells in normal mature gonads, a significant general decrease was observed in all spermatic and reproductive parameters analyzed. These outcomes raise concerns about the viability of GH-transgenesis appliance to aquaculture and the environmental risks at the light of Trojan gene hypothesis. PMID:23618946

Figueiredo, Marcio A; Fernandes, Raíssa V; Studzinski, Ana L; Rosa, Carlos E; Corcini, Carine D; Junior, Antônio S Varela; Marins, Luis F

2013-04-04

38

A colo-urachal-cutaneous fistula in an 88-year-old male  

PubMed Central

Introduction Urachus anomalies are remnants of the urachus, an embryonic connection between the fetal bladder and umbilicus. These anomalies usually remain asymptomatic but can cause symptoms in case of infection. An extremely rare complication of symptomatic urachal remnants is fistulizing to adjacant viscera. We describe the first case of diverticulitis associated sigmoid-urachal-cutaneous fistula. Case report An 88-year-old male visited the outpatient clinic with intermittent bleeding and gassy discharge from his umbilicus. Examination showed a normal looking umbilicus with a small fissure at the bottom in which a 10 cm probe could be inserted. Laparotomy revealed a fistula extending from the umbilicus to a pus filled cyst superior to the bladder. A second fistula between the cyst and a mid-sigmoid diverticulum was identified. The involved sigmoid segment was resected. Pathological examination demonstrated no malignancy. Discussion Urachal remnants are extremely rare in adults. They typically present with abdominal pain or palpable masses. Additional imaging can aid the diagnostic process. Conclusion Due to the risk of recurrence and malignant transformation complete surgical excision of urachal anomalies is the treatment of choice. This can be done in a 1-step or 2-step procedure.

Peters, Anna L.; Kruijer, Marjan J.P.; Wiese, Hans; Verbeek, Paul C.M.

2011-01-01

39

A case report of Gordon's syndrome in a 20-year-old male with free medical family history.  

PubMed

Gordon's syndrome is a rare autosomal dominant disease that manifests in childhood. It is characterized by hypertension, hyperkalemic hyperchloremic metabolic acidosis, low renin and usually normal aldosterone levels, and it is sensitive to thiazide diuretics. A 20-year-old male with a history of diagnosed Gordon's syndrome was referred to a nephrology clinic for evaluation. The patient, who was under treatment with hydrochlorothiazide, had been diagnosed with Gordon's syndrome at the age of 11, when he presented hypertension and episodes of hyperkalemic hyperchloremic metabolic acidosis. However, none of his relatives had been diagnosed with this syndrome. Therefore, we assume that our patient might be a case of de novo gene mutation. PMID:23340132

Kostakis, Ioannis D; Tsoukalas, Nikolaos G; Aravantinos, Dionysios C; Gkizis, Ilias G; Cholidou, Kyriaki G; Papadopoulos, Dimitris P

40

Deep recurrent infection of the hip after tumoral resection in an 18-years old male-a case report  

PubMed Central

An 18 years old male was referred to us 4 years after major tumoral surgery. In 2002 he was diagnosed with Ewing sarcoma of the proximal two–thirds of his left femur. Wide resection of the tumor was performed, with a makeshift implant one–stage reconstruction, followed by a combination of chemo and radiotherapy for another 6 months. Eight months after surgery a deep infection of the hip developed, and despite antibiotic treatment and two consecutive debridments and lavage the results were negative. When we first saw the patient in 2006, he still had an active infection in his left hip and a septic general appearance. A two–stage revision was performed and a modular tumoral reconstruction was implanted. At two years follow up the patient presents no signs of recurrence neither of the infection nor of the primary tumor.

Negrusoiu, M

2008-01-01

41

QUALITY OF LIFE FOLLOWING SPINAL CORD INJURY FOR 20-40 YEAR OLD MALES LIVING IN SRI LANKA  

Microsoft Academic Search

This study aimed to find out the quality of life achieved by 20-40 year old males living in Sri Lanka who have either received rehabilitation or have not following spinal cord injury. The study used both quantitative and qualitative methods to answer the research question. Data was collected by using a questionnaire within semi- structured interviews with 20 SCI males,

Paul Chappell; Sheila Wirz

2003-01-01

42

Osteolytic myxopapillary ependymoma with marked hyaline degeneration in a 72-year-old male: A case report  

PubMed Central

Myxopapillary ependymomas (MPEs) are uncommon and account for ?15% of all ependymomas. The current study presents a case of rare spinal MPE with abnormal hyaline degeneration. The patient was a 72-year-old male with a 10-month history of lower back pain. Magnetic resonance imaging revealed a mass involving the L4 and L5 vertebrae with local bone destruction. The tumor was completely resected. Histologically, the majority of the tumor exhibited low cellularity. A marked change in hyaline was observed in the blood vessels and stroma. In specific areas, the tumor showed reticular or tubular patterning embedded in hyaline materials. The tumor cells were cuboidal to columnar in shape with strong immunostaining for glial fibrillary acidic protein and S-100. A fluorescence in situ hybridization analysis for amplification of the epidermal growth factor receptor gene was negative. The results of pathological and immunohistochemical studies were consistent with the ependymal nature of neoplastic cells.

WANG, HAI; ZHANG, ZHIYUAN; MAKKI, MOHAMMAD SHAHIDUL; SHI, QUNLI

2013-01-01

43

A Puzzle of Hemolytic Anemia, Iron and Vitamin B12 Deficiencies in a 52-Year-Old Male  

PubMed Central

A 52-year-old male with no significant past medical history reports increasing generalized fatigue and weakness for the past 2 weeks. Physical examination reveals jaundice and pallor without organomegaly or lymphadenopathy. His hemoglobin was 5.9?g/dL with a mean corpuscular volume of 87.1?fL and elevated red blood cell distribution width of 30.7%. His liver function test was normal except for elevated total bilirubin of 3.7?mg/dL. Serum LDH was 701?IU/L, and serum haptoglobin was undetectable. Further investigation revealed serum vitamin B12 of <30?pg/mL with elevated methylmalonic acid and homocysteine level. In addition, serum ferritin and transferrin saturation were low. The patient was diagnosed with hemolytic anemia secondary to vitamin B12 deficiency with concomitant iron deficiency anemia.

Liana, Palacci; Ali, Alaa M.; Gilman, Alan D.

2013-01-01

44

Sepsis Caused by Veillonella parvula Infection in a 17YearOld Patient with X-Linked Agammaglobulinemia (Bruton's Disease)  

Microsoft Academic Search

Received 3 March 2006\\/Returned for modification 4 April 2006\\/Accepted 26 April 2006 A case of a male, 17-year-old, X-linked agammaglobulinemia patient with bacteremia caused by Veillonella parvula, without a defined primary site of infection, is presented. The report demonstrates that V. parvula should not be regarded as a nonpathogenic microorganism, at least not in patients with certain forms of immunodeficiency

Magdalena Strach; Maciej Siedlar; Danuta Kowalczyk; Marek Zembala; Tomasz Grodzicki

2006-01-01

45

Primary non-Hodgkin's lymphoma of gingiva in a 28-year-old HIV-positive patient  

PubMed Central

Non-Hodgkin's lymphoma (NHL) is seldom seen in the oral cavity, and has been reported with some frequency in HIV-positive patients. Oral HIV-related lymphomas exhibit an aggressive course and can mimic other oral tumors and infections that make early recognition and diagnosis difficult. This paper presents a case of NHL on the gingiva of a 28-year-old HIV-positive male patient.

Basavaraj, K. F.; Ramalingam, Karthikeyan; Sarkar, Amitabha; Muddaiah, Savitha

2012-01-01

46

[Primary plexiform ameloblastoma in the sinonasal tract of a 49-year-old female patient. Case report].  

PubMed

Sinonasal ameloblastoma is a rare tumor, which most frequently affects male patients in the 6th-7th decade. We report on the case of 49-year-old female patient presenting with nasal obstruction. Computed tomography revealed a solid and hypodense mass filling the maxillary sinus and the nasal cavity. The histological examination showed a plexiform ameloblastoma without significant bone erosion. Viewing this together with the literature review, we suggest that sinonasal ameloblastoma in female patients becomes apparent approximately one decade earlier than in male patients. This tumor should be considered in the differential diagnosis of unilateral sinonasal symptoms. PMID:23644482

Hansen, T; Bogumil, A; Koutsimpelas, D

2013-07-01

47

Successful prosthetic fitting of a 73-year-old hip disarticulation amputee patient with cardiopulmonary disease  

Microsoft Academic Search

Patients with hip disarticulation (HD) require high energy expenditure for successful prosthetic ambulation. Thus, older patients are rarely fitted with an HD prosthesis. To our knowledge there are no reports of gait analysis following successful prosthetic fitting of an elderly HD amputee patient with systemic cardiopulmonary disease. We report the case of successful prosthetic ambulation in a 73-year-old man with

Robert D. McAnelly; Manouchehr Refaeian; Dennis G. O'Connell; Gregory D. Powell; Nicolas E. Walsh

1998-01-01

48

Renal Replacement in End-Stage Renal Disease Patients over 75 Years Old  

Microsoft Academic Search

Background: Over the last decade, the age of dialysis patients has been increasing steadily in several units in Canada. Our main objective was to assess prevalence, co-morbidity and outcome of ESRD patients over 75 years old at the beginning of dialysis treatment in our center. As a group, they were compared to younger dialysis patients treated simultaneously. Methods: In the

Isabelle Létourneau; Denis Ouimet; Marc Dumont; Vincent Pichette; Martine Leblanc

2003-01-01

49

An Atypical Eating Disorder with Crohn's Disease in a Fifteen-Year-Old Male: A Case Study.  

ERIC Educational Resources Information Center

|Discusses how 6 months after psychological intervention for an eating disorder, a 15-year-old male was diagnosed with Crohn's disease, a chronic inflammatory bowel disease. Addresses need for additional training for those from traditional school and counseling psychology programs. Advocates a team approach and consultations. (RJM)|

Holaday, Margot; And Others

1994-01-01

50

Evaluation of specific anaerobic power in 12-14-year-old male rowers.  

PubMed

No previous study had applied the modified Wingate rowing test to young athletes (i.e. children and adolescents). The aims of this study were to evaluate the trial-to-trial reliability of a rowing-modified Wingate test in a group of 12-14-year-old rowers (n=98) and to compare anaerobic power values among the 12-, 13-, and 14-year-old rowers after accounting for differences in physical maturity and body size. Each subject performed two "all-out" 30-s trials on a Concept II rowing ergometer. The trials were separated by a 15-min active recovery period, which included walking and stretching and ensured the participants' full recovery. The test proved to be highly reliable, with coefficients of variations of 2.4 and 2.9% (CI=2.1-3.4%) and intraclass correlation coefficients of 0.994 and 0.996 (CI=0.991-0.997) for mean power and peak power, respectively. The ANCOVA analyses accounting for differences in body size and level of physical maturity (assessed using indices of pubic hair) and the Bonferroni post hoc tests identified the 14-year-olds as having significantly greater adjusted mean power and peak power values (P<0.01) than the other two age groups, while the differences between the 12- and 13-year-olds in terms of mean power and peak power were not significant. Our findings indicate (1) that the rowing-modified Wingate test may be reliably used for the assessment of specific anaerobic performance in 12-14-year-old rowers and (2) that factors other than physical maturity and body size are partly responsible for the increase in anaerobic power during growth. PMID:18762452

Mikuli?, Pavle; Ruzi?, Lana; Markovi?, Goran

2008-08-31

51

The energy cost of household and garden activities in 55- to 65-year-old males  

Microsoft Academic Search

This study measured the energy expenditure of four self-paced household and garden tasks to determine whether 55- to 65-year-old men performed them at a moderate intensity [3–6 metabolic equivalents (METs)] and to predict the activity intensity via indirect methods. Resting metabolic rate and oxygen consumption were measured using Douglas bags in 50 men \\u000a who performed self-perceived moderate paced walking and

Simon M. Gunn; Anthony G. Brooks; Robert T. Withers; Christopher J. Gore; John L. Plummer; John Cormack

2005-01-01

52

Massive intra-abdominal imatinib-resistant gastrointestinal stromal tumor in a 21-year-old male.  

PubMed

Gastrointestinal stromal tumors (GISTs) in adolescence are far less common than adult GISTs and have varied GIST genotypes that present diagnostic and therapeutic challenges. Here, we discuss a 21-year-old male with diagnosis of unresectable, imatinib-resistant GIST. At initial evaluation, a neoadjuvant treatment approach was recommended. As such, the patient received imatinib over the course of one year. Unfortunately, the GIST increased in size, and a subsequent attempt at surgical resection was aborted fearing infiltration of major vascular structures. The patient was then referred to our institution, at which time imatinib therapy was discontinued. Surgical intervention was again considered and the patient underwent successful resection of massive intra-abdominal GIST with total gastrectomy and Roux-en-Y esophagojejunostomy. Since pediatric GISTs are typically resistant to imatinib, we performed genotype analysis of the operative specimen that revealed KIT mutations associated with imatinib sensitivity and resistance. Given the sequencing data and operative findings, the patient was started postoperatively on sunitinib. This case illustrates the importance of understanding both adult and pediatric GISTs when implementing appropriate treatment regimens. Since the genotype of GISTs dictates phenotypic behavior, mutational analysis is an important component of care especially for adolescents whose disease may mirror the pediatric or adult population. PMID:23983708

Falor, Ann; Arrington, Amanda K; Luu, Carrie; Schoellhammer, Hans F; Ko, Michelle; Chow, Warren; D'Apuzzo, Massimo; Park, Jinha; Kim, Joseph

2013-08-04

53

[Abdominal mass and colicky pain in a 16-years-old patient].  

PubMed

We report about a 16-years-old patient with a newly developed palpable mass and pain in the epigastrium. On computed tomography, a trichobezoar was diagnosed. Complementary history, gathered retrospectively, revealed trichophagia and swallowing of chewing gum. Gastroscopic disintegration of the trichobezoar was unsuccessful and it therefore had to be removed by open surgery. PMID:19809981

Michel, S C A; Keerl, A; Kubik-Huch, R A; Geyer, M

2009-10-01

54

A Case of Idiopathic Central Serous Chorioretinopathy in a 12-year-old Male Treated with Bevacizumab  

PubMed Central

A 12-year-old male presented with a chief complaint of a 1-month-history of decreased visual acuity in his right eye. The patient had no past history of steroid use or other systemic diseases. On fundus examination, which included fluorescent angiography (FAG) and optical coherence tomography (OCT), the patient was diagnosed with idiopathic central chorioretinopathy, whose clinical course was monitored without any specific treatments. At the time of admission, the best-corrected visual acuity was 0.5 in the right eye and 1.0 in the left eye. On fundoscopy, a serous detachment of 1 disc diameter in size was observed in the posterior pole. According to the FAG and the OCT, serous neurosensory detachment was present. After two months of monitoring the clinical course, the best corrected visual acuity in the right eye was 0.8, and there was improvement of neurosensory retinal detachment. However, OCT detected recurrence after five months, and the corrected visual acuity was decreased to 0.6. Bevacizumab was then injected into the vitreous cavity. Complete resolution of the subretinal fluid resulted eight months later, and the corrected visual acuity improved to 1.0.

Kim, Yu Cheol; Kim, Si Dong

2012-01-01

55

Conservative management of a 31 year old male with left sided low back and leg pain: a case report  

PubMed Central

Objective: This case study reported the conservative management of a patient presenting with left sided low back and leg pain diagnosed as a left sided L5-S1 disc prolapse/herniation. Clinical features: A 31-year-old male recreational worker presented with left sided low back and leg pain for the previous 3–4 months that was exacerbated by prolonged sitting. Intervention and Outcome: The plan of management included interferential current, soft tissue trigger point and myofascial therapy, lateral recumbent manual low velocity, low amplitude traction mobilizations and pelvic blocking as necessary. Home care included heat, icing, neural mobilizations, repeated extension exercises, stretching, core muscle strengthening, as well as the avoidance of prolonged sitting and using a low back support in his work chair. The patient responded well after the first visit and his leg and back pain were almost completely resolved by the third visit. Summary: Conservative chiropractic care appears to reduce pain and improve mobility in this case of a L5-S1 disc herniation. Active rehabilitative treatment strategies are recommended before surgical referral.

Howell, Emily R.

2012-01-01

56

Tongue cancer in young patients: case report of a 26-year-old patient  

PubMed Central

Introduction This article presents the case of a 26-year-old woman with tongue cancer. The median age at the diagnosis of the tongue’s cancer is 61?years. Only approximately 2% of patients are diagnosed before the age of 35. Case presentation Our patient survived acute myeloid leukemia (AML) before her second year. She had been having recurrent, poorly healing aphtae on the right side of the tongue for a period of months before the symptoms of the tongue cancer appeared. As a treatment a partial glossectomy was conducted on the right side and a neck dissection of levels I-III. Than a reconstruction of the tongue with a radialis free vascularised flap from left side was performed. Discussion It should be always looked for the causal factor in young patients with a neoplasm. There is strong evidence for second malignant neoplasms in survivors of childhood cancer.

2012-01-01

57

Strong ERG Positivity in Papillary Intralymphatic Angioendothelioma of the Testis of a 24-Year-Old Male: A Case Report.  

PubMed

Papillary intralymphatic angioendothelioma is a rare, low-grade neoplasm of lymphatic channels that usually presents intradermally or subcutaneously. We report the case of a 24-year-old male presenting with an isolated intratesticular palpable mass and symptoms of testicular pain. Preoperative ultrasound examination showed an irregular, heterogeneous mass. Subsequent surgery and pathologic assessment revealed a papillary intralymphatic angioendothelioma (PILA), formerly known as Dabska tumor within the lymphatic spaces. PMID:23607024

Schultheis, Anne M; Sandmann, Mareike; Steurer, Stefan

2013-03-31

58

Magnetic nasal foreign bodies in a 9-year-old male: opposites attract when it comes to nasal foreign bodies.  

PubMed

We report the case of a 9-year-old male who developed nasal ulcerations from magnets which were placed in his nose, and became attracted to each other across the nasal septum. The magnets came from a non-penetrating earring. Normally harmless, but when attracted to each other magnets can cause ulcerations and possibly perforation of the nasal septum and should be removed urgently whenever encountered. PMID:15911018

Greenberg, Mark; Magit, Anthony

2005-07-01

59

[Outpatient treatment of selective mutism: long-standing selective mutism in a 17-year-old male].  

PubMed

The present case report describes the successful treatment of a 17 year old male adolescent suffering for 10 years from selective mutism. Following a summary review of recent publications on therapy approaches, the report describes the treatment concept in the present case, including detailed assessment of co-morbid disorders, motivation for change, behaviour therapy with supporting drug intervention, and intensive co-operation with parents and other caretakers. PMID:20047174

Herdener-Pinnekamp, Katharina; Gundelfinger, Ronnie; Steinhausen, Hans-Christoph

2010-01-01

60

Predictors of smoking cessation in 50–66-year-old male Taiwanese smokers: A 7-year national cohort study  

Microsoft Academic Search

The study was aimed to determine the predictors of smoking cessation in 50–66-year-old male Taiwanese smokers. The study analyzed datasets of the “Survey of Health and Living Status of the Elderly in Taiwan” (SHLSET), a population-based longitudinal cohort study conducted by the Bureau of Health Promotion of Taiwan. Binary logistic regression analysis was performed to determine the association of demographic,

Alan Chung-hong Tsai; Yun-Ann Lin; Hsin-Jen Tsai

61

Correlates of weight loss and muscle-gaining behavior in 10- to 14-year-old males and females  

Microsoft Academic Search

Background. This study examined the influence of appearance and social acceptance esteem, awareness and internalization of media stereotypes, body size acceptance, and teasing on the weight loss and muscle-gaining behaviors of 10- to 14-year-old boys and girls. Methods. Male (n = 670) and female (n = 788) students were drawn from one of four public senior middle schools (grades 6-8)

Gail McVey; Stacey Tweed; Elizabeth Blackmore

2005-01-01

62

Strong ERG Positivity in Papillary Intralymphatic Angioendothelioma of the Testis of a 24-Year-Old Male: A Case Report  

PubMed Central

Papillary intralymphatic angioendothelioma is a rare, low-grade neoplasm of lymphatic channels that usually presents intradermally or subcutaneously. We report the case of a 24-year-old male presenting with an isolated intratesticular palpable mass and symptoms of testicular pain. Preoperative ultrasound examination showed an irregular, heterogeneous mass. Subsequent surgery and pathologic assessment revealed a papillary intralymphatic angioendothelioma (PILA), formerly known as Dabska tumor within the lymphatic spaces.

Schultheis, Anne M.; Sandmann, Mareike; Steurer, Stefan

2013-01-01

63

The postoperative cardiovascular arrest of a 5-year-old male: an initial presentation of Duchenne's muscular dystrophy.  

PubMed

Anesthesia may be administered to patients with Duchenne's muscular dystrophy, but cases are reported in which apparently healthy children suffer hyperkalemic cardiac arrest. We present the case of a 5-year-old boy whose muscular dystrophy was discovered following a fatal, perioperative cardiac arrest in the postanesthesia care unit. PMID:16430414

Girshin, Michael; Mukherjee, Jana; Clowney, Ross; Singer, Lewis P; Wasnick, John

2006-02-01

64

Predictors of smoking cessation in 50-66-year-old male Taiwanese smokers: a 7-year national cohort study.  

PubMed

The study was aimed to determine the predictors of smoking cessation in 50-66-year-old male Taiwanese smokers. The study analyzed datasets of the "Survey of Health and Living Status of the Elderly in Taiwan" (SHLSET), a population-based longitudinal cohort study conducted by the Bureau of Health Promotion of Taiwan. Binary logistic regression analysis was performed to determine the association of demographic, socioeconomic, lifestyle and health-related variables with changes in smoking status at baseline, or with subsequent changes in smoking status in 50-66-year-old male Taiwanese. Functional impairment was the strongest predictor of quitting smoking for 50-66-year-old Taiwanese men. Other factors including a first hospitalization, emergency visit, or diagnosis of heart disease, quitting drinking, living with a spouse and older age were associated with increased likelihood of quitting smoking. Men with long smoking history, heavy daily cigarette consumption and more formal education were less likely to quit. Results suggest that functional decline is the major cause for quitting smoking for older Taiwanese men. Physical impairment and traumatic diseases that cause physical impairment have the most impact whereas "silent diseases" such as hypertension or diabetes have little impact. These findings should be useful for designing target-specific intervention strategies for older male Taiwanese smokers. PMID:21889808

Tsai, Alan Chung-hong; Lin, Yun-Ann; Tsai, Hsin-Jen

2011-09-01

65

Disproportionately severe calcinosis cutis in an 88-year-old patient with CREST syndrome  

Microsoft Academic Search

.?  An 88-year-old woman with CREST syndrome (calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasias)\\u000a presented with hyperglycemia, intravascular depletion, and atrial fibrillation. The patient was found to have unusually severe\\u000a calcinosis cutis in both legs extending from the knees to the ankles bilaterally, as well as Raynaud’s phenomenon, sclerodactyly,\\u000a and telangiectasias. The patient was normocalcemic and normophosphatemic. Although subcutaneous calcification

Jacob M. Buchowski; Nicholas U. Ahn; Uri M. Ahn; Edward F. McCarthy; M. B. Mehta

2001-01-01

66

Alumina-on-Alumina Hip Arthroplasty in Patients Younger Than 30 Years Old  

Microsoft Academic Search

THA in patients younger than 30 years old presents challenges: the initial technical challenge relates to the initial disease\\u000a that often causes deformities making reconstruction difficult, while the long-term challenge is wear and subsequent osteolysis\\u000a and component loosening. Ceramic-on-ceramic prostheses may represent a valuable option to reduce wear. We retrospectively\\u000a studied 101 patients (132 hips) with ceramic-on-ceramic prostheses implanted from 1977

R. Nizard; D. Pourreyron; A. Raould; D. Hannouche; L. Sedel

2008-01-01

67

Macular Hole after Laser In Situ Keratomileusis in a 26-Year-Old Patient  

PubMed Central

The purpose of this study is to describe the 26-year-old patient with developed macular hole after bilateral laser in situ keratomileusis (LASIK). A macular hole with sharp margins and irregular surface of surrounding retina appeared in the left eye of the female 26-year-old patient two months after LASIK for correction of myopia (followup of 6 months). Although the best corrected visual acuity (BCVA) after LASIK was 1.0, after the macular hole has developed BCVA became 0.5. After surgery, the final visual acuity recovered to 0.7. Macular hole may develop after LASIK for myopia correction due to unknown changes of vitreoretinal interface. Complete informed consent must be obtained from patients with high myopic eyes before LASIK.

Oshitari, Toshiyuki; Sakurai, Madoka; Baba, Takayuki; Yamamoto, Shuichi

2013-01-01

68

Alveolar Rhabdomyosarcoma in a 68YearOld Patient Identified by Cytogenetic Analysis of Bone Marrow  

Microsoft Academic Search

Pancytopenia and fulminant disseminated intravascular coagulation in a 68-year-old woman suggested an acute hematologic malignancy. However, cytogenetic analysis on a bone marrow sample revealed a near-tetraploid karyotype with an isochromosome 1q and a translocation (2;13)(q35;q14), which was suggestive of an alveolar rhabdomyosarcoma (ARMS). This diagnosis was subsequently confirmed by indirect immunohistochemistry. ARMS has not yet been observed in a patient

Reinhard Stindl; Michael Fiegl; Heinz Regele; Heinz Gisslinger; Martin J. Breitenseher; Christa Fonatsch

1998-01-01

69

Homicides among 15-19-year-old males--United States, 1963-1991.  

PubMed

In 1991, nearly half (13,122 [49%]) of the 26,513 homicide victims in the United States were males aged 15-34 years. In addition, among males in this age group, homicide accounted for 18% of all deaths and was the second leading cause of death (Table 1). During 1963-1991, the pattern of homicide rates changed substantially; the change was greatest for males aged 15-19 years, for whom rates increased substantially (Figure 1). This report summarizes these trends and presents strategies for violence prevention and intervention. PMID:7935300

1994-10-14

70

The Memory Performance of Selected Depressed and Nondepressed Nine- to Eleven-Year-Old Male Children.  

ERIC Educational Resources Information Center

This study compared the performance of depressed and nondepressed males (ages 9-11) on tasks requiring overt rehearsal and free recall. The depressed children rehearsed less both in repetition of words and in the size of their rehearsal sets and recalled fewer words. It is concluded that depressed children have short-term memory processing…

Osborn, Robert G.; Meador, Darlene M.

1990-01-01

71

Pathology Case Study: Neck Mass in a 34-Year-Old Male  

NSDL National Science Digital Library

The University of Pittsburgh School of Medicine presents a case study on neck mass as part of its Ear, Nose and Throat Pathology series. This case provides comparative alternative images of similar cases and slides of known diseases for easy comparison. In addition, the student may examine the medical history of and symptoms presented by the patient. The images and information provided here allow students to examine a patient, and could be used in lecture or as a class assignment.

Schubert, Eric

2007-08-01

72

Allometric scaling of peak oxygen uptake in male roller hockey players under 17 years old.  

PubMed

Peak oxygen uptake (V?O2peak) is routinely expressed in litres per minute and by unit of body mass (mL·kg(-1)·min(-1)) despite the theoretical and statistical limitations of using ratios. Allometric modeling is an effective approach for partitioning body-size effects in a performance variable. The current study examined the relationships among chronological age (CA), skeletal age (SA), total body and appendicular size descriptors, and V?O2peak in male adolescent roller hockey players. Seventy-three Portuguese, highly trained male athletes (CA, 15.4 ± 0.6 years; SA, 16.4 ± 1.5 years; stature, 169.9 ± 6.9 cm; body mass, 63.7 ± 10.7 kg; thigh volume, 4.8 ± 1.0 L) performed an incremental maximal test on a motorized treadmill. Exponents for body size descriptors were 2.15 for stature (R(2) = 0.30, p < 0.01) and 0.55 for thigh volume (R(2) = 0.46, p < 0.01). The combination of stature or thigh volume and CA or SA, and CA(2) or SA(2), increased the explained variance in V?O2peak (R(2) ranged from 0.30 to 0.55). The findings of the allometric model combining more than 1 body size descriptor (i.e., stature and thigh volume) in addition to SA and CA(2) were not significant. Results suggest that thigh volume and SA are the main contributors to interindividual variability in aerobic fitness. PMID:23713531

Valente-Dos-Santos, João; Sherar, Lauren; Coelho-E-Silva, Manuel J; Pereira, João R; Vaz, Vasco; Cupido-Dos-Santos, Amândio; Baxter-Jones, Adam; Visscher, Chris; Elferink-Gemser, Marije T; Malina, Robert M

2013-04-01

73

[Unusual skin alterations in a 72-year-old patient with multiple myeloma].  

PubMed

We report on a 72-year-old female patient with multiple myeloma who presented with alopecia and eye-catching alterations of the skin and the nails. A biopsy of the skin could confirm the diagnosis of immunoglobulin light chain (AL) amyloidosis, which was also suspected of having affected other organs. After six cycles of a cytoreductive therapy with bortezomib and dexamethasone a very good partial response of the multiple myeloma was seen and an improvement in the skin and nail alterations could be achieved. PMID:22274304

Hart, C; Wurm, S; Hafner, C; Andreesen, R; Grube, M

2012-04-01

74

Noninvasive assessment of cardiomyopathy in normotensive diabetic patients between 20 and 50 years old  

SciTech Connect

To further the understanding of diabetic heart disease, we tested the hypothesis that an asymptomatic group of normotensive diabetic patients between 20 and 50 years old had a restrictive cardiomyopathy independent of clinically significant coronary artery disease. Quantitative two-dimensional echocardiography and stress myocardial perfusion scintigraphy were performed to detect and characterize the cardiac abnormalities in this study group comprising 88 patients with rigorously classified diabetes and 65 volunteer control subjects. Diabetic patients were shown to have a mildly reduced left ventricular end-diastolic volume index: 50.1 +/- 8.2 and 52.1 +/- 14.7 mL/m2 for patients with type I and type II diabetes, respectively, versus 58.9 +/- 11.7 mL/m2 for control subjects. The left ventricular diastolic filling was also impaired in diabetic patients as reflected by a lower atrial emptying index: 0.73 +/- 0.24 and 0.76 +/- 0.3 for type I and type II diabetics, respectively, compared with 1.14 +/- 0.24 for control subjects. Exercise tolerance was normal in subjects with type I diabetes and slightly reduced in subjects with type II diabetes. Only one patient developed regional ischemia on thallium exercise testing. Using a comprehensive, noninvasive approach, we have shown that asymptomatic normotensive patients with type I or type II diabetes who were between 20 and 50 years old had a restrictive cardiomyopathy characterized by mildly reduced left ventricular end-diastolic volume and altered left ventricular compliance independent of critical coronary artery disease.

Bouchard, A.; Sanz, N.; Botvinick, E.H.; Phillips, N.; Heilbron, D.; Byrd, B.F. 3d.; Karam, J.H.; Schiller, N.B. (Univ. of California, San Francisco (USA))

1989-08-01

75

Persistent left superior vena cava with an absent right superior vena cava in a 72-year-old male with multivessel coronary artery disease.  

PubMed

Congenital anomalies of systemic veins are usually asymptomatic and foundincidentally during ultrasonography, computed tomography (CT) or magneticresonance examinations performed for other clinical indications. Persistent leftsuperior vena cava (PLSVC) with absent right superior vena cava (RSVC) is thecongenital aberration in the thoracic venous system which occurs in only 0.09%to 0.13% of patients who have congenital heart defects. In this paper, we presentthe extremely rare case of a 72-year-old male with PLSVC associated withan absence of RSVC, referred for coronary CT angiography. Multidetector CTangiography is a powerful tool for the detection of venous anomalies, which isessential before invasive procedures such as the implantation of pacemakers. PMID:24068691

Szymczyk, K; Polguj, M; Szymczyk, E; Majos, A; Grzelak, P; Stefa?czyk, L

2013-08-01

76

Mature Ovarian Teratoma with Carcinoid Tumor in a 28-Year-Old Patient  

PubMed Central

Introduction. Coexistence of carcinoid tumor inside a mature cystic teratoma is an extremely rare phenomenon, especially in young women. We present the case of a 28-year-old woman diagnosed with a right ovarian carcinoid and treated uneventfully with conservative surgical approach. Case Report. A 28-year-old woman, gravid 0, parity 0, presented to our department for her annual gynecological examination and Pap smear test. During her examination, a mobile cystic mass was detected in the right lower abdomen. Ultrasound indicated a right ovarian mass 10.5 × 6.3?cm, confirmed by CT scan. Further investigation revealed AFP levels (1539?ng/mL). The ovarian mass was excised by laparoscopy, leaving intact the remaining right ovary. Frozen sections showed a mature cystic teratoma. However, paraffin sections revealed the presence of a small carcinoid within the teratoma's gastric-type mucosa. The patient was set to a close followup. Nine months postoperatively, ultrasound pelvis imaging and CT scan of the abdomen as well as serum tumor markers have shown no evidence of recurrence disease. Conclusion. Despite the weak evidence, fertility spare surgical approach for women wanting to preserve their genital tract might be a reasonable option.

Petousis, Stamatios; Kalogiannidis, Ioannis; Margioula-Siarkou, Chrysoula; Traianos, Alexandros; Miliaras, Dimosthenis; Kamparoudis, Apostolos; Mamopoulos, Apostolos; Rousso, David

2013-01-01

77

A western Eurasian male is found in 2000-year-old elite Xiongnu cemetery in Northeast Mongolia.  

PubMed

We analyzed mitochondrial DNA (mtDNA), Y-chromosome single nucleotide polymorphisms (Y-SNP), and autosomal short tandem repeats (STR) of three skeletons found in a 2,000-year-old Xiongnu elite cemetery in Duurlig Nars of Northeast Mongolia. This study is one of the first reports of the detailed genetic analysis of ancient human remains using the three types of genetic markers. The DNA analyses revealed that one subject was an ancient male skeleton with maternal U2e1 and paternal R1a1 haplogroups. This is the first genetic evidence that a male of distinctive Indo-European lineages (R1a1) was present in the Xiongnu of Mongolia. This might indicate an Indo-European migration into Northeast Asia 2,000 years ago. Other specimens are a female with mtDNA haplogroup D4 and a male with Y-SNP haplogroup C3 and mtDNA haplogroup D4. Those haplogroups are common in Northeast Asia. There was no close kinship among them. The genetic evidence of U2e1 and R1a1 may help to clarify the migration patterns of Indo-Europeans and ancient East-West contacts of the Xiongnu Empire. Artifacts in the tombs suggested that the Xiongnu had a system of the social stratification. The West Eurasian male might show the racial tolerance of the Xiongnu Empire and some insight into the Xiongnu society. PMID:20091844

Kim, Kijeong; Brenner, Charles H; Mair, Victor H; Lee, Kwang-Ho; Kim, Jae-Hyun; Gelegdorj, Eregzen; Batbold, Natsag; Song, Yi-Chung; Yun, Hyeung-Won; Chang, Eun-Jeong; Lkhagvasuren, Gavaachimed; Bazarragchaa, Munkhtsetseg; Park, Ae-Ja; Lim, Inja; Hong, Yun-Pyo; Kim, Wonyong; Chung, Sang-In; Kim, Dae-Jin; Chung, Yoon-Hee; Kim, Sung-Su; Lee, Won-Bok; Kim, Kyung-Yong

2010-07-01

78

Variegate porphyria in a 46-year-old patient taking sibutramine for weight loss.  

PubMed

The acute hepatic porphyrias can cause life-threatening attacks of neurovisceral symptoms that mimic other acute medical conditions. Variegate porphyria caused by mutations in the protoporphyrinogen oxidase (PPOX) gene is a latent disorder characterized by exacerbations induced by fasting, alcohol consumption or certain drugs. We describe the case of a 46-year-old female patient presenting with a first episode of symptomatic porphyria after 10 d of sibutramine treatment for weight loss. Genetic analysis showed a heterozygous R168H hot spot mutation in the PPOX gene. A putative effect of sibutramine on the hepatic haem biosynthetic pathway and reduced food intake have likely caused this exacerbation of a porphyria attack. Although this may be the first case report of this kind, the risk of acute porphyria should be considered in patients using pharmacotherapy for obesity. PMID:19845869

Reiser, M; Eickmann, S; Haverkamp, T; Finckh, U

2009-10-21

79

[Repair of post-infarction interventricular communication in a 81-year-old patient].  

PubMed

Post-infarction interventricular fistula (IVF) is a complication with a poor prognosis, particularly when it occurs very early after myocardial necrosis, when it is wide in diameter and even more so if it is at a posterior site, and if there are associated lesions which require surgery. An operation is often considered as contraindicated in cases where the patient is elderly. The authors report on the case of an 81-year-old diabetic patient operated for a wide post-infarctus posterior IVF and aorto-coronary artery bypass surgery. The operation is still a clinical success after 23 months of follow-up, showing that old age is not an absolute contraindication for surgery in cases of post-infarction IVF. PMID:2264707

Aldakar, M; Dauptain, J; Farge, C; Charon, P; Lefort, J F; Cazal, J

1990-09-01

80

[Initial clinical experience of early cardiac rehabilitation for very elderly patients over 85 years old following open heart surgery].  

PubMed

In this study, we evaluated the initial clinical experience of early cardiac rehabilitation( CR) for very elderly patients over 85 years old after open heart surgery. From September 2007 to January 2011, 7 consecutive patients (85~90 years, mean 85.9 years, male:female=4:3) who underwent cardiac surgery in our institute were selected. Preoperative activity of daily living (ADL) scores were similar in all cases, and 1 patient used a cane for walking. Preoperative New York Heart Association (NYHA) classification was class III :3, class IV:4. Three patients were admitted for acute congestive heart failure approximately 1 month prior to surgery. Standard open heart surgery using bioprosthesis was performed: 3 patients underwent mitral valve replacement( MVR), 3 had aortic valve replacement( AVR), and 1 had tricuspid valve replacement (TVR). Postoperative clinical course was uneventful, and the mean time of ventilator support was 12.1 hours. Thereafter, early CR was introduced at the intensive care unit( ICU) in all patients, and the mean time of introduction of early rehabilitation was 1.7 days. In the last 4 cases, early CR was done the 1st day following surgery. CR was effectively performed in all cases without any problems or cardiac events, and all patients improved enough to leave their beds at 3~7 days, a mean of 4.4 days after surgery. The mean hospital stay after surgery was 30.9 days( 23 ~ 42 days), almost all patients were able to walk independently, and ADL scores at discharge were improved. Only 2 patients required a cane for walking. Postoperative NYHA classification was improved to class I :5, class II :2. From these results, early CR for very elderly patients over 85 years old could be a safe and effective tool to improve and maintain the ADL and quality of life following surgical intervention. PMID:22647324

Furukawa, Hiroshi; Kangai, Keisuke; Minami, Kouhei; Ohura, Keisuke; Ochi, Yusuke; Ikumoto, Hiroko; Fujimoto, Masumi; Aono, Hitoshi; Samukawa, Masanobu

2012-06-01

81

Cardiac rehabilitation of a 77-year-old male runner: consideration of the athlete, not the age.  

PubMed

A 77-year-old geologist with coronary artery disease enrolled in our cardiac rehabilitation program after successful placement of a drug-eluting stent. Unlike the typical sedentary cardiac patient in his age group, he loved to run. He expressed a strong desire to return to his sport, and completion of a self-assessment scale confirmed his high level of athletic identity. Despite the patient's advanced age and long history of unstable blood pressure, we were able to design a special exercise program that enabled him to train safely and thereby reach his goal. When developing a cardiac rehabilitation plan, health care professionals should consider the patient's athletic identity, not just his or her chronological age. PMID:19169393

Schmid, Jack; Adams, Jenny; Cheng, Dunlei

2009-01-01

82

Sorry... It was not a sore throat!! Castleman's disease in a 19-year-old, previously normal, young patient  

PubMed Central

A 19-year-old male patient presented to the emergency department with a small amount of haemoptysis preceded by coughing and sneezing. He came back from Portugal a week ago. His physical examination was unremarkable and his routine blood tests were normal apart from a slightly raised D dimer. His chest x-ray revealed a mediastinal mass, which appeared on CT as a right-sided mediastinal mass with low attenuation compressing the superior vena cava. The CT angiogram showed multiple arterial supply from the brachiocephalic, vertebral and bronchial arteries; they drained into internal jugular, subclavian and azygous system. CT-guided biopsy was performed followed by operative excision of the mass 5 weeks later. Both histology results confirmed a hyaline vascular variant of Castleman's disease with no evidence of any malignancy.

Bagouri, E O; Faruqi, F

2011-01-01

83

Generalized Peritonitis Secondary to Spontaneous Perforation of Pyometra in a 63-Year-Old Patient  

PubMed Central

Spontaneous perforation of pyometra resulting in generalized diffuse peritonitis is extremely uncommon. Herein, we report the case of a 63-year-old woman who presented to emergency department with a 2-day history of severe diffuse abdominal pain, high-grade fever, nausea, and vomiting. Acute abdomen series was done, and upright plain chest radiograph showed free air under diaphragm. A noncontrast-enhanced computed tomography scan showed a significantly distended fluid-filled uterus measuring 10 × 7.8 × 10?cm, in addition to a single focus of perforation involving the uterine fundus and associated with presence of free air within the nondependant area. No evidence of ascites or pelvi-abdominal lymphadenopathy was identified. A preoperative diagnosis of generalized peritonitis secondary to spontaneous perforation of uterus was established. Subsequently, patient underwent urgent exploratory laparotomy which revealed pus-filled uterus with perforated fundus. Diagnosis of generalized peritonitis secondary to spontaneous perforation of pyometra was established. Consequently, patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, as well as thorough drainage and irrigation of pelvi-abdominal cavity. Postoperatively, patient was admitted to intensive care unit. Histopathological examination of uterus was negative for malignancy, and surgical culture grew Streptococcus constellatus. Patient had an uneventful recovery. Moreover, a brief literature review on pyometra is presented.

Abu-Zaid, Ahmed; AlOmar, Osama; Nazer, Ahmed; Azzam, Ayman; Abudan, Zainab; Al-Badawi, Ismail

2013-01-01

84

Alumina-on-Alumina Hip Arthroplasty in Patients Younger Than 30 Years Old  

PubMed Central

THA in patients younger than 30 years old presents challenges: the initial technical challenge relates to the initial disease that often causes deformities making reconstruction difficult, while the long-term challenge is wear and subsequent osteolysis and component loosening. Ceramic-on-ceramic prostheses may represent a valuable option to reduce wear. We retrospectively studied 101 patients (132 hips) with ceramic-on-ceramic prostheses implanted from 1977 to 2004. As a result of the long span of time, different implant designs and modes of fixation were used. The average age of the patients was 23.4 ± 5 years (range, 13–30 years), and the main indication for THA was femoral head necrosis. The minimum followup was 1 year (mean, 6.9 years; range, 1–26.5 years). We documented 17 revisions (13%) for aseptic loosening. Twelve were for isolated acetabular loosening, two for isolated femoral loosening, and three for loosening of both components. Survivorship was 82.1% at 10 years and 72.4% at 15 years. Inferior survivorship was observed for THA performed after secondary arthritis related to slipped capital epiphysis or trauma. Limited osteolysis was observed in one hip. The main limiting factor in this series was the fixation of the acetabular component. However, improvements in the design and in the mode of fixation of this component should enhance long-term results. Level of Evidence: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.

Pourreyron, D.; Raould, A.; Hannouche, D.; Sedel, L.

2008-01-01

85

Abdominal and back pain in a 65-year-old patient with metastatic prostate cancer  

PubMed Central

Objective Prostate cancer remains the second leading cause of cancer-related deaths, and African American men are affected with this disease disproportionately in terms of incidence and mortality. The purpose of this article is to present a case report that illustrates the importance of a careful evaluation, including a comprehensive historical review and appropriate physical and laboratory assessment, of a patient with back pain and seemingly unrelated symptoms. Clinical Features A 65-year-old African American man presented to a chiropractic clinic after experiencing lower back pain for 1 month. The digital rectal examination was unremarkable, but the serum prostate-specific antigen was markedly elevated. A suspicion of metastatic prostate cancer resulted in subsequent referral, further diagnostic evaluation, and palliation. Intervention and Outcome The patient was referred for medical evaluation and palliation of his condition. Spinal decompression surgery of the thoracic spine was initiated, resulting in weakness and paresthesia in the lower limbs bilaterally. The patient died because of the complications associated with the medical interventions and the disease about 12 months after the referral. Conclusion Chiropractic physicians should maintain a high degree of suspicion for catastrophic causes of back-related complaints, such as metastatic prostate cancer. The Prostate Cancer Prevention Trial Risk Calculator, a research validated instrument, should be used in the assessment of prostate cancer risk. Performance of the digital rectal examination and of the prostate-specific antigen determination remains integral in the clinical assessment of the health status in aging men, with or without back pain.

Johnson, Theodore L.

2010-01-01

86

A critical increase in right-to-left shunt after acute myocardial infarction in a 68-year-old male with tetralogy of Fallot.  

PubMed

A male patient with tetralogy of Fallot accompanied by aortic regurgitation had maintained sufficient exercise capacity for a number of decades with the status of acyanotic tetralogy of Fallot. When he was 67 years old, he suffered a posterior wall acute myocardial infarction and direct percutaneous coronary angioplasty successfully revascularised the target lesion in the left circumflex artery. However, a few months after the onset of the myocardial infarction, his shortness of breath became clinically significant and was associated with increased right-to-left shunt and increased right ventricular end-diastolic pressure, as well as hypoxia. At 68 years old, therefore, total corrective repair of the tetralogy with replacement of the aortic and pulmonary valves was performed. The patient was asymptomatic after the successful operation. This report suggests that coronary artery disease can be one of the potential factors in inducing critical hemodynamic changes in aging patients with congenital heart disease, especially those who have a shunt between the right and left chambers. The unique clinical course is described with some discussion of the repair of tetralogy in adults. PMID:15858950

Izawa, Atsushi; Sekimura, Noriyuki; Uchikawa, Shin-ichiro; Yazaki, Yoshikazu; Kinoshita, Osamu; Owa, Mafumi; Kubo, Keishi; Ikeda, Uichi; Sekiguchi, Morie; Kitahara, Hiroto; Amano, Jun; Imamura, Hiroshi

2005-01-01

87

Upper Cervical Chiropractic Care For A Nine-Year-Old Male With Tourette Syndrome, Attention Deficit Hyperactivity Disorder, Depression, Asthma, Insomnia, and Headaches: A Case Report  

Microsoft Academic Search

Objective: To review the effectiveness of chiropractic care using an upper cervical technique in the case of a nine-year- old male who presented with Tourette Syndrome (TS), Atten- tion Deficit Hyperactivity Disorder (ADHD), depression, asthma, insomnia, and headaches. Clinical Features: This nine-year-old boy suffered from asthma and upper respiratory infections since infancy; head- aches since age 6; TS, ADHD, depression

Erin L. Elster

2003-01-01

88

Neurotoxicities and behavioral changes in a 12?year?old male exposed to dicofol, an organochloride pesticide  

Microsoft Academic Search

The case of a 12?yr?old male exposed to a substantial amount of dicofol, a DDT analog, is presented. The patient was still contaminated 3 wk after exposure. Blood and fat analysis documented the presence of dicofol. The patient demonstrated subjective and objective evidence of neurological injury, which resolved. Other organ injury was not present. Cognitive and emotional difficulties persisted over

James E. Lessenger; Nell Riley

1991-01-01

89

A 17-year-old male with pseudotumor cerebri secondary to performance-enhancing steroids triggering venous thrombosis in the brain.  

PubMed

This article is a case report of a 17-year-old male who presented with a headache and blurry vision. He subsequently was noted to have papilledema on a fundoscopic examination and an initial normal magnetic resonance imaging and computed tomography of his head; his condition was, therefore, diagnosed as pseudotumor cerebri. A subsequent magnetic resonance venography of his head revealed venous thrombosis, and other investigations revealed an elevated factor VIII level as well as a mutation at the MTHFR locus, consistent with an elevated risk for hypercoagulability. In addition, he admitted to steroid usage for purposes of performance enhancement in baseball. The patient's condition eventually improved with acetazolamide and serial lumbar punctures. Steroids have been linked to predisposition to hypercoagulable states, but there are no reports identified by these authors that link performance-enhancing steroids with pseudotumor cerebri as a result of a coagulation dyscrasia. PMID:19131586

DeSena, Allen D; Weimer, Stephen

2009-01-08

90

A rare case of an aldosterone secreting metastatic adrenocortical carcinoma and papillary thyroid carcinoma in a 31-year-old male  

PubMed Central

We report a rare synchronous presentation of adrenocortical carcinoma (ACC) and papillary thyroid carcinoma (PTC). A 31-year-old male first presented with a large left adrenal mass that was identified during the workup for refractory hypertension due to hyperaldosteronism. The mass was removed surgically with pathology showing ACC. The patient was then treated with adjuvant radiation therapy and mitotane chemotherapy. Four months post ACC resection, metastatic ACC to the right upper lung and PTC in the left lobe of the thyroid were found in surveillance imaging. He subsequently developed pulmonary, contralateral adrenal and brain metastases from his ACC. Li Fraumeni syndrome and Multiple Endocrine Neoplasia Type I (MEN I) were considered, but testing of both P53 and menin genes showed no mutation. We also performed a review of the literature and found three similar cases, however gene mutation analysis was not performed..

Wanta, Stephen M.; Basina, Marina; Chang, Steven D.; Chang, Daniel T.; Ford, James M.; Greco, Ralph; Kingham, Kerry; Merritt, Robert E.; Kunz, Pamela L.

2011-01-01

91

Multimodality treatment of a complex series of parallel pathologies in a 16-year-old male that ultimately leads to bilateral hip arthroplasty surgery: A case report  

PubMed Central

INTRODUCTION Femoral head osteonecrosis is associated with significant sequelae for the patient in the long-term. A combination of factors are thought to contribute to the pathophysiology behind this debilitating disease process. PRESENTATION OF CASE We report on a 16-year-old adolescent male requiring staged bilateral hybrid hip arthroplasty within 3 years of diagnosis of acute lymphoblastic leukaemia that ran a complicated course of multimodality treatment. DISCUSSION The case examines the literature on femoral head osteonecrosis in this population cohort and the challenge for the orthopaedic surgeon in the management of this increasingly prevalent condition. CONCLUSION In a young population cohort, it is important to have arthroplasty surgery as part of the management armamentarium, especially when coupled with complex pathology.

Cullen, Emmet; Quinlan, John; Fogarty, Esmond; Keogh, Peter

2012-01-01

92

Pyonephrosis and urosepsis in a 41-year old patient with spina bifida: Case report of a preventable death  

PubMed Central

Background Urological complications are the major cause of ill health in patients with spina bifida. Urinary sepsis accounted for the majority of admissions in patients with spina bifida. As the patient grows older, changes occur in the adult bladder, leading to increases in storage pressure and consequent risk of deterioration of renal function, which may occur insidiously. Case presentation A 34-year-old male spinal bifida patient had been managing neuropathic bladder by penile sheath. Intravenous urography revealed normal kidneys. This patient was advised intermittent catheterisations. But self-catheterisation was not possible because of long, overhanging prepuce and marked spinal curvature. This patient developed repeated urine infections. Five years later, ultrasound examination of urinary tract revealed hydronephrotic right kidney with echogenic debris within the collecting system. There was no evidence of dilatation of the ureter near the vesicoureteric junction. The left kidney appeared normal. There was no evidence of calculus disease seen in either kidney. Indwelling urethral catheter drainage was established. Two years later, MAG-3 renogram revealed normal uptake and excretion by left kidney. The right kidney showed little functioning tissue. Following a routine change of urethral catheter this patient became unwell. Ultrasound examination revealed hydronephrotic right kidney containing thick hyper-echoic internal septations and debris in the right renal pelvis suspicious of pyonephrosis. Under both ultrasound and fluoroscopic guidance, an 8 French pig tail catheter was inserted into the right renal collecting system. 150?ml of turbid urine was aspirated immediately. This patient developed large left pleural effusion, collapse/consolidation of the left lower lobe, a large fluid collection in the abdomen extending into the pelvis and expired twenty days later because of sepsis and respiratory failure. Conclusion Although penile sheath drainage may be convenient for a spina bifida patient and the carers, hydronephrosis can occur insidiously. With recurrent urine infections, hydronephrotic kidney can become pyonephrosis, which is life-threatening. Therefore, every effort should be made to carry out intermittent catheterisations along with antimuscarinic drug therapy.

2012-01-01

93

[Hyperthyroidism, eosinophilia, and fever in a 64-year-old patient].  

PubMed

We report on a male patient suffering from loss of weight, fatigue, fever, eosinophilia, and hyperthyreoidism. The echocardiogram revealed a left atrial mass originating from the posterior mitral leaflet. In combination with the constitutional symptoms a left atrial myxoma was diagnosed. The tumor was surgically removed. Postoperatively therapy with corticosteroids and thiamazole was stopped. During follow-up, eosinophilia and hyperthyreodism could no longer be detected. PMID:22996359

Tack, C; Stierle, U; Heydrich, D; Petersohn, S; Sievers, H H; Feller, A C; Schneider, B

2012-10-01

94

A 21YearOld Patient with Acute Myeloid Leukemia and Bilateral Pulmonary Infiltrates  

Microsoft Academic Search

A 21-year-old man, day 62 postconsolidation chemotherapy for acute myeloid leukemia M4 (AML-M4), complained of dyspnea, fever and feeling ill at a routine follow-up visit. Four and a half months earlier he was diagnosed with AML-M4. The diagnosis of AML-M4 was made on June 23, 1999. A Hickman line was inserted and intensive induction chemotherapy with standard dose daunorubicin, ARA-C

J. Theron; G. Ainslie; J. W. Schneider; W. D. Bates; C. T. Bolliger

2001-01-01

95

Fatality Assessment and Control Evaluation (FACE) Report: A Sixteen-Year-Old Male Died After Falling 27 Feet at a Residential Construction Site in Alabama.  

National Technical Information Service (NTIS)

A 16-year-old male framing construction crew member (the victim) died after falling 27 feet from the third story of a residential dormitory construction site. The victim was moving roof trusses that were to be anchored in place using a nail gun. He was su...

2001-01-01

96

Fatality Assessment and Control Evaluation (FACE) Report for Michigan: 29-Year Old Male Hispanic Landscape Laborer Dies When Nine Foot Trench Collapses.  

National Technical Information Service (NTIS)

On February 1, 2006, a 29-year old male Hispanic landscape laborer died when the two-foot wide, sixteen-foot long and nine-foot deep trench he was working in collapsed and covered him with soil. The victim and four other laborers had been hand digging the...

2007-01-01

97

Recurrent pulmonary embolism in a 13-year-old male homozygous for the prothrombin G20210A mutation combined with protein S deficiency and increased lipoprotein (a)  

Microsoft Academic Search

We report the case of a 13-year-old male presenting with recurrent symptoms of respiratory distress after a trauma of the lower limb. Pulmonary symptoms had been misinterpreted for several weeks and only marked symptoms of deep venous (DVT) and caval vein thrombosis later prompted the correct diagnosis of DVT and embolic events and subsequently a successful thrombolytic therapy. The case

Andrea Kosch; Ralf Junker; Cornelia Wermes; Ulrike Nowak-Göttl

2002-01-01

98

Infective endocarditis complicated with left atrioventricular fistula in a 20-year-old patient. A case study  

PubMed Central

Intracardiac fistulas are rare complications of infective endocarditis. We report an unusual case of successful surgical repair of intracardiac fistula between the left ventricle and the left atrium in the course of infective endocarditis in a 20-year-old patient. According to this we conclude that timely diagnosis, proper antibiotic treatment, and early surgical intervention should improve the outcomes of infective endocarditis complications.

Pawlowski, Witold; Jander, Slawomir; Bartczak, Karol; Maciejewski, Marek; Jaszewski, Ryszard

2011-01-01

99

Males Have Greater "g": Sex Differences in General Mental Ability from 100,000 17- to 18-Year-Olds on the Scholastic Assessment Test  

ERIC Educational Resources Information Center

|In this study we found that 17- to 18-year old males averaged 3.63 IQ points higher than did their female counterparts on the 1991 Scholastic Assessment Test (SAT). We analysed 145 item responses from 46,509 males and 56,007 females (total N = 102,516) using a principal components procedure. We found (1) the "g" factor underlies both the SAT…

Jackson, Douglas N.; Rushton, J. Philippe

2006-01-01

100

Males have greater g: Sex differences in general mental ability from 100,000 17- to 18-year-olds on the Scholastic Assessment Test  

Microsoft Academic Search

In this study we found that 17- to 18-year old males averaged 3.63 IQ points higher than did their female counterparts on the 1991 Scholastic Assessment Test (SAT). We analysed 145 item responses from 46,509 males and 56,007 females (total N=102,516) using a principal components procedure. We found (1) the g factor underlies both the SAT Verbal (SAT-V) and the

Douglas N. Jackson; J. Philippe Rushton

2006-01-01

101

Males Have Greater "g": Sex Differences in General Mental Ability from 100,000 17- to 18-Year-Olds on the Scholastic Assessment Test  

ERIC Educational Resources Information Center

In this study we found that 17- to 18-year old males averaged 3.63 IQ points higher than did their female counterparts on the 1991 Scholastic Assessment Test (SAT). We analysed 145 item responses from 46,509 males and 56,007 females (total N = 102,516) using a principal components procedure. We found (1) the "g" factor underlies both the SAT…

Jackson, Douglas N.; Rushton, J. Philippe

2006-01-01

102

Type 2 segmental Darier's disease in a twelve-year-old Nigerian male--a case report.  

PubMed

Darier's disease is an autosomal dominant disorder characterized clinically by presence of keratotic papules in a seborrheic distribution, nail involvement and mucosal lesions. There are several clinical variants of Darier's disease, but few cases of segmental Darier's disease have been described in the literature. We describe a 12-year-old boy with type 2 mosaic phenotype. This unique clinical variant of Darier's disease has been described very rarely. PMID:20120148

Yusuf, S M; Mohammed, A Z; Uloko, A E

103

Sequential bilateral total knee arthroplasty under 1 anesthetic in patients > or = 75 years old: complications and functional outcomes.  

PubMed

The objectives of this study were to determine the perioperative surgical and medical risks associated with sequential bilateral total knee arthroplasty (TKA) in patients > or = 75 years old and to assess their functional status and overall level of satisfaction at follow-up. Study participants were 82 consecutive patients > or = 75 years old who underwent a sequential bilateral TKA and 82 matched patients who underwent a unilateral TKA. There were 46 postoperative complications in the bilateral TKA group compared with 27 in the unilateral TKA group (P = .003). Postoperative cardiovascular complications were significantly greater in the sequential bilateral TKA group and were associated significantly with preoperative cardiovascular comorbidity. The mean Modified Hospital for Special Surgery knee score was rated as good (mean, 63.5 out of 80), and 95% of patients rated their knees as excellent or good at follow-up. Sequential bilateral TKA in patients > or =75 years old results in high patient satisfaction and good functional status at follow-up; however, there is an increased risk of cardiovascular complications during the postoperative period in bilateral sequential TKA patients when compared with a matched cohort of unilateral TKA patients. PMID:11307122

Adili, A; Bhandari, M; Petruccelli, D; De Beer, J

2001-04-01

104

Recurrent symptomatic bilateral bundle branch block in a 74-year-old patient with a prosthetic aortic valve  

Microsoft Academic Search

This report concerns a 74-year-old patient who had undergone aortic valve replacement 11 years earlier. On admission, the patient complained of shortness of breath when climbing two flights of stairs; there was no history of dizziness, fainting or sensations of arrhythmias. An ECG at rest showed first-degree atrioventricular (A-V) block together with left bundle branch block (LBBB). On bicycle ergometry,

Günter Lehmann; Isabel Deisenhofer; Bernhard Zrenner; Claus Schmitt

1999-01-01

105

[A 38-year-old patient with gastroenteritis and unusual liver lesions].  

PubMed

A 38-year-old female presented with symptoms of gastroenteritis including fatigue and epigastric pain. An abdominal ultrasound indicated on the basis of raised liver values showed multiple liver lesions. However, additional imaging using contrast-enhanced ultrasound (CEUS), computer tomography (CT) as well as a magnetic resonance tomography (MR) failed to clarify the diagnosis. A fine needle biopsy revealed the histological diagnosis of peliosis hepatis. After discontinuing oral contraceptive medication, follow-up showed a steady state with clinical well being for at least 24 months.Peliosis hepatis is a rare hepatic disorder involving "bloody cysts" in the liver. Aetiology and pathogenesis remain unclear, but medication or toxins as possible triggering factors are discussed. Different clinical courses have been reported, including total asymptomatic state, unspecific fatigue, epigastric pain, as well as fulminant cases with liver rupture and bleeding complications. PMID:22614102

Heinrich, E; Gutberlet, K; Ockenga, J

2012-08-01

106

Bladder carcinoma in a 31-year-old female spina bifida patient with an auto-augmented bladder  

Microsoft Academic Search

We present the case of a 31-year-old spina bifida patient presenting with a poorly differentiated T3N1M0 bladder carcinoma\\u000a with sarcomatoid differentiation in an auto-augmented bladder. She underwent a radical cystectomy and a bilateral lymph node\\u000a dissection. However, only 10 months after the onset of her symptoms, she died after major lymphatic metastases had developed\\u000a in the small pelvis. This case report

Paul W. Veenboer; Laetitia M. O. de Kort

107

Recurrent atrioventricular nodal re-entrant tachycardia treated with percutaneous ablation in a 75-year old patient undergoing intermittent hemodialysis  

Microsoft Academic Search

A 75-year old man with long-term arterial hypertension was diagnosed in 1998 with stage 3 chronic kidney disease due to hypertensive\\u000a nephropathy. Since May 2004 the patient has been treated with intermittent hemodialysis. Since 1998 he has been hospitalized\\u000a several times because of palpitations in the course of paroxysmal tachycardia with narrow QRS complexes. Initially, class\\u000a I antiarrhythmic agents were

Aniela M. Ratajewska; Wojciech W. Banachowicz; Alicja E. Grzegorzewska

2009-01-01

108

Attitudes toward homosexual activity and gays as friends: A national survey of heterosexual 15? to 19?year?old males  

Microsoft Academic Search

Heterosexual adolescent males’ negative attitudes toward gays were examined using data from a 1988 national survey of male youth 15 to 19 years of age. Results indicated that the vast majority of young males, 89%, found sex between two men “disgusting,” and only 12% felt confident that they could befriend a gay person. Multivariate analyses revealed, as expected, that respondents

William Marsiglio

1993-01-01

109

The impact of young age on locoregional recurrence after doxorubicin-based breast conservation therapy in patients 40 years old or younger: How young is 'young'?  

SciTech Connect

Purpose: The aim of this study was to investigate whether patients <35 years old have similar risk of locoregional recurrence after breast conservation therapy compared with patients 35 to 40 years old. Methods and materials: We retrospectively reviewed records of 196 consecutive patients {<=}40 years old who received breast conservation therapy (BCT) from 1987 to 2000 for breast cancer and compared outcomes between patients <35 years old with patients 35 to 40 years old. The majority of patients received neoadjuvant chemotherapy as part of their treatment. Multivariate analysis was performed to assess risk factors for locoregional recurrence. Results: After a median follow-up of 64 months, 22 locoregional recurrences (LRR) were observed. Twenty patients developed locoregional recurrence as their first site of relapse. Two patients had bone-only metastases before their locoregional recurrence. On multivariate analysis, age <35 years was associated with a statistically significant increased risk of locoregional recurrence. The 5-year rate of locoregional control was 87.9% in patients <35 years old compared with 91.7% in patients 35 to 40 years old (p = 0.042). Conclusions: Our finding supports an increased risk of locoregional recurrence as a function of younger age after breast conservation therapy, even among young patients 40 years old and younger.

Oh, Julia L. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)]. E-mail: joh@mdanderson.org; Bonnen, Mark [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Outlaw, Elesyia D. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Schechter, Naomi R. [Department of Radiation Oncology, University of California-San Francisco Mt. Zion Comprehensive Cancer Center, San Francisco, CA (United States); Perkins, George H. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Strom, Eric A. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Babiera, Gildy [Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Oswald, Mary Jane [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Allen, Pamela K. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Thames, Howard D. [Department of Biostatistics and Applied Mathematics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Buchholz, Thomas A. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)

2006-08-01

110

Pheochromocytoma in an 8-year-old patient with multiple endocrine neoplasia type 2A: Implications for screening.  

PubMed

Childhood pheochromocytoma in the setting of multiple endocrine neoplasia type 2 (MEN2) remains rare and has not been reported under the age of 12. We present an 8-year-old female with known MEN 2A, C634Y RET mutation, diagnosed with a 6?cm pheochromocytoma requiring laparoscopic adrenalectomy. Given this patient's age at diagnosis, screening guidelines should recommend annual screening beginning at age 8 for patients with MEN 2B or MEN 2A codons 630 or 634 RET mutations. J. Surg. Oncol. 2013 108:203-206. © 2013 Wiley Periodicals, Inc. PMID:23868299

Rowland, Kathryn J; Chernock, Rebecca D; Moley, Jeffrey F

2013-07-19

111

Primary angiosarcoma of the ovary with prominent fibrosis of the ovarian stroma. Case report of an 81-year old patient  

PubMed Central

Primary angiosarcoma of the ovary (AS) is a rare entity with only 31 reported cases. The majority are pure angiosarcomas, the remainder are associated either with teratomas or conventional epithelial tumors. More than 50% of ovarian AS are disseminated at the time of diagnosis, the minority is detected in stage I. The prognosis of ovarian angiosarcoma in general is poor. Most reports refer to younger individuals, aged from 7 to 46 years, and only 2 case reports could be found for patients older than 64 years. Here we present a very unusual case of angiosarcoma in a 81-year-old patient.

2011-01-01

112

Performance measures of 16– to 86-year-old males and females on the auditory verbal learning test  

Microsoft Academic Search

This study reports Auditory Verbal Learning Test (AVLT) data for 153 adults in age groups spanning seven decades, with approximately equal numbers of males and females and matched for intelligence, education, and occupation. Overall performance deteriorated with increased age, females performing better than males. Older subjects recalled fewer words, were more susceptible to information overload during input, showed diminished retrieval

Gina Geffen; K. J. Moar; A. P. Ohanlon; C. R. Clark; L. B. Geffen

1990-01-01

113

A novel mutation (Cys145-->Stop) in Bruton's tyrosine kinase is associated with newly diagnosed X-linked agammaglobulinemia in a 51-year-old male.  

PubMed Central

BACKGROUND: X-linked agammaglobulinemia (XLA) is a severe, life-threatening disease characterized by failure of B cell differentiation and antibody production and is associated with mutations in Bruton's tyrosine kinase (Btk). The proband in this study is a 51-year-old male presenting with chronic nasal congestion, recurrent sinusitis, sporadic pneumonia, and pronounced B cell deficiency. A family history suggestive of an X-linked immunodeficiency disease was noted. MATERIALS AND METHODS: cDNA was synthesized from mRNA prepared from peripheral blood mononuclear leukocytes. Btk cDNA amplified by polymerase chain reaction (PCR) was subjected to both manual and automated DNA sequencing. A DNA sequence corresponding to exons 6 and 7 of Btk was amplified from genomic DNA. Western blot analysis employed both polyclonal and monoclonal antibodies to Btk and reaction patterns were obtained both by chemiluminescence and an in vitro kinase assay. RESULTS: A mutation (Cys145-->Stop) was identified in Btk cDNA and was confirmed in amplified exon 6 of genomic DNA from both the proband and an affected nephew. Neither Btk nor a truncated peptide was detected in Western blot analyses of peripheral blood mononuclear cell lysates. CONCLUSIONS: The C145A mutation reported here is novel. This family study is extraordinary in that affected male members who did not undergo aggressive medical management either succumbed to complications in early life or survived into later life. The proband is the oldest de novo diagnosed patient with XLA reported to date. Images FIG. 2 FIG. 3

Kornfeld, S. J.; Haire, R. N.; Strong, S. J.; Tang, H.; Sung, S. S.; Fu, S. M.; Litman, G. W.

1996-01-01

114

Involved-field radiotherapy is effective for patients 70 years old or more with early stage non-small cell lung cancer  

Microsoft Academic Search

Background and purposeNon-small cell lung cancer (NSCLC) accounts for approximately 80–85% of all lung cancers, especially in patients 70 years old or more. In this study, we investigated the efficacy and safety of involved-field radiotherapy (IFRT) for patients 70 years old or more with early stage NSCLC.

Hui Ming Yu; Yun Fang Liu; Jin Ming Yu; Jie Liu; Yuxia Zhao; Ming Hou

2008-01-01

115

The frequency of latent prostate carcinoma in autopsies of over 50 years old males, the Iranian experience  

PubMed Central

Background Latent adenocarcinoma of prostate refers to cases who present no obvious sign or symptom during their life spans and the tumor is incidentally found at postmortem examination. Its frequency can be very important in epidemiologic investigations, prevention and treatment. No previous study has been done in this regard in Iran and the studies performed in other countries show various results. The aim of present study is to determine the frequency of latent prostate carcinoma by studying the corpora of men above 50 years old referred to forensic medicine organization in Tehran in 2008 and 2009. Methods In this study, 149 men aged above 50 who had died of different reasons and undergone autopsy were examined. Their prostates were excised and the slides were studied for the presence of adenocarcioma and prostatic intraepithelial neoplasia (PIN). In each case, age, weight of prostate, location of lesion, and grading according to Gleason's system were determined and the results were analyzed by SPSS software (version 16). Results Out of 149 cases, 34(22.8%) had low grade PIN, 26(17.4%) high grade PIN, and 14(9.4%) invasive adenocarcinoma. Most of the tumors were located in posterior lobe of prostate and they were more frequent in older cases (>65 years of age) and heavier prostates (p value <0.05). All invasive adenocarciomas were accompanied by PIN. Conclusion Worldwide studies show lower prevalence of latent carcinoma of prostate in Asian men than white European ones. Considering the absence of such studies in Iran, a larger study to compare and find out the precise rate of this kind of carcinoma, is recommended.

Balvayeh, Payam; Imamhadi, Mohammad Ali; Lotfi, Maryam

2012-01-01

116

A rare noncardiac cause for acute myocardial infarction in a 13-year-old patient.  

PubMed

A case of ST-segment elevation myocardial infarction in an adolescent patient is presented. The patient presented with resting angina and echocardiographic evidence of wall motion abnormalities in the inferior and posterior segments. The patient was known to have metastatic hepatocellular carcinoma. Tumor was seen in the left inferior pulmonary vein and is proposed to be the source of embolism-causing myocardial infarction. Secondary to intracranial metastatic lesions, the patient was treated conservatively with opiates, nitrates, and beta-blockers. This case is an opportunity to review the causes and management of myocardial infraction in pediatric patients and represents a rare cause of embolic myocardial infraction. PMID:14667262

Aragon, Joseph

117

Evaluation of Health Related Quality of Life in 6–18 Years Old Patients with Acute Leukemia during Chemotherapy  

Microsoft Academic Search

Objective  To evaluate the quality of life (QOL) of Iranian children with acute leukemia during chemotherapy.\\u000a \\u000a \\u000a \\u000a Methods  One hundred patients between 6 to 18-years-old were selected by convenient sampling method. EORTC QLQ-C30 Questionnaire was\\u000a completed by their parents’ help. Demographic information such as age, sex and type of leukemia were also collected. These\\u000a data were evaluated by SPSS software, Chi-square and independent

Soheila Zareifar; Mohammad Reza Farahmandfar; Nader Cohan; Forough Modarresnia; Sezaneh Haghpanah

118

[Pitfalls in Diagnosis and Therapy for CMV Colitis in a 30-Year-Old HIV-Positive Patient].  

PubMed

We report on a 30-year-old patient who presented with bloody diarrhoea. After initially, assuming a previously not diagnosed ulcerative colitis, an immunosuppressive therapy was initiated, a week later an HIV infection stage C2 according to the CDC classification, complicated by CMV viraemia, was diagnosed. In this case report the course of treatment with highly active antiretroviral therapy (HAART), ganciclovir and prednisolone is reported and discussed on the basis of histological, immunohistochemical and microbiological findings. The case illustrates the difficulty to distinguish between ulcerative colitis, immune reconstitution syndrome, CMV colitis and HIV-associated diarrhoea. PMID:23955139

Walldorf, J; Lübbert, C

2013-08-16

119

Percutaneous extraction of a coiled, 20-year-old lead in a patient with cardiac resynchronization therapy.  

PubMed

A 61-year-old patient with a 20-year history of permanent pacemaker implantation and half--a-year cardiac resynchronization therapy using a left ventricular lead placed via surgical approach was admitted for extraction of an old coiled right ventricular lead, which triggered ventricular arrhythmia and created a risk of pulmonary embolism. The lead was extracted via the left femoral vein in two stages: untying a loop on the lead using a pig-tail catheter and Dotter basket followed by traction and dissection of adhesions using a Byrd dilator sheath. Dissection of the old lead from the active right ventricular one posed special technical problems. PMID:18698547

Ma?ecka, Barbara; Kutarski, Andrzej; Bednarek, Jacek; Zabek, Andrzej; Lelakowski, Jacek

2008-01-01

120

TUNEL and growth factor expression in the prefrontal cortex of Alzheimer patients over 80 years old.  

PubMed

To elucidate factors underlying the increased risk of developing Alzheimers disease (AD) in older individuals, the prefrontal cortices of younger (58-79 years) and of older (over 80 years) AD patients were examined by silver impregnation, TUNEL assay and immunohistochemistry for hyperphosphorylated tau, LDH and two growth factors (BDNF, NGF). Quantitative data were compared with those of age-matched controls. TUNEL-positive cells were mainly located in superficial cortical layers of younger and in deeper layers of older AD patients. Their density was more than 5 times higher in older AD than in younger AD (p < or = 0.05), but apoptotic cell morphology was rarely seen. Significantly more neuronal somas were contacted by degenerating fibers both in younger and older AD cortices. Density of tau-immunoreactive cells, which were virtually absent in controls, was twice as high in older AD patients as in younger AD individuals (p < or = 0.05). In younger AD, TUNEL positive cells generally lacked tau immunoreaction, whereas in older AD, most cells were double-labeled for hyperphosphorylated tau and TUNEL (p < or = 0.05). Numerical density of BDNF-immunoreactive cells was significantly reduced by 20 percent in older AD patients, compared to both control individuals and younger AD patients, whereas density of NGF-positive cells was the same in all patient groups examined. The distinct differences between younger and older AD patients suggest a faster progression of AD in older patients. PMID:20377991

Lorke, D E; Wai, M S M; Liang, Y; Yew, D T

121

Transcatheter aortic valve implantation and four-year follow up in a 99-year-old patient.  

PubMed

Transcatheter aortic valve implantation (TAVI) has emerged as a life-saving therapy in patients with severe aortic valve stenosis who are considered to be high-risk surgical candidates. However, there is a paucity of data on the long-term survival and quality-of-life in very old patients undergoing TAVI. Here, the case is reported of a now 104-year-old patient who underwent percutaneous transfemoral TAVI with a CoreValve prosthesis at the age of 99 years; details of his four-year outcome data are also provided. To best of the authors' knowledge, this patient is the oldest reported to have undergone TAVI, and is currently living with good functional status more than four years after the intervention. PMID:23798219

Jabs, Alexander; Kilic, Teoman; Schnelle, Nalan; Post, Felix; Vosseler, Markus; Vahl, Christian-Friedrich; Münzel, Thomas; Hink, Ulrich

2013-03-01

122

Perinatal care for incarcerated patients: a 25-year-old woman pregnant in jail.  

PubMed

More than 6 million men and 1 million women are under US correctional control, be it jail, prison, probation, or parole. On any given day, about 250,000 women and adolescent girls are behind bars, a number well in excess of those documented for all other sovereign nations. Moreover, women and girls represent the fastest-growing segment of the prison and jail populations. Approximately 75% of these women are mothers of minor children (leaving 200,000 children "motherless") and as many as 10,000 may be pregnant. Primarily designed for male offenders, the US correctional system is struggling to meet the specialized needs of its female inmates. Although incarceration during pregnancy is both stressful and dehumanizing, most studies paradoxically document better outcomes for pregnancies managed behind bars than for women of similar socioeconomic status whose pregnancies are managed in the community. Using the case of Ms A as a springboard for discussion, the issues, benefits, and challenges of caring for an incarcerated pregnant woman are addressed, as is the importance of family planning services to those about to be released. PMID:21304069

Clarke, Jennifer G; Adashi, Eli Y

2011-02-08

123

Immunogenicity of the quadrivalent human papillomavirus (type 6/11/16/18) vaccine in males 16 to 26 years old.  

PubMed

Human papillomavirus (HPV) infection can lead to significant disease in males, including anogenital warts, intraepithelial neoplasias, and several types of oral and anogenital cancers. The quadrivalent HPV (type 6/11/16/18) L1 virus-like particle (VLP) vaccine (qHPV vaccine; Gardasil) has recently been demonstrated to prevent persistent infection and associated disease related to vaccine HPV types in males. We report the overall immunogenicity results from a trial of the quadrivalent HPV vaccine in males. Overall, 3,463 heterosexual men and 602 men who had sex with men were enrolled into a randomized, placebo-controlled, double-blind safety, immunogenicity, and efficacy study. Serum samples were collected prior to vaccination at day 1 and at months 7, 24, and 36 postvaccination. Immunogenicity was evaluated with a multiplex, competitive Luminex immunoassay. Almost all subjects (97.4 to 99.2%) seroconverted for vaccine HPV types by month 7. At month 36, 88.9%, 94.0%, 97.9%, and 57.0% of subjects were still seropositive for HPV-6, -11, -16, and -18, respectively. For all vaccine HPV types, black subjects had significantly higher antibody titers at month 7 than did both Caucasian and Asian subjects. An anamnestic antibody response was seen in men seropositive before vaccination. The vaccine was highly immunogenic in males 16 to 23 years of age; responses were comparable to those observed in women. Furthermore, the immune responses were consistent with the established efficacy of the vaccine in the prevention of incident and persistent HPV infection, anogenital warts, and anal intraepithelial neoplasia. PMID:22155768

Hillman, Richard J; Giuliano, Anna R; Palefsky, Joel M; Goldstone, Stephen; Moreira, Edson D; Vardas, Eftyhia; Aranda, Carlos; Jessen, Heiko; Ferris, Daron G; Coutlee, Francois; Marshall, J Brooke; Vuocolo, Scott; Haupt, Richard M; Guris, Dalya; Garner, Elizabeth I O

2011-12-07

124

[Noninvasive studies of the left ventricular systolic function in patients over 65 years old].  

PubMed

Left ventricular functions were assessed in 96 patients (26 men, 70 women aged over 65 years; mean age 74.6 +/- 6.3 years) with various cardiovascular diseases (arterial hypertension, coronary heart disease, cardiomyopathy, various cardiac defects) by comparing various left-ventricular time intervals obtained from resting ECGs, apex cardiograms, carotid-pulse curves and phonocardiograms with left-ventricular ejection fractions by echocardiography. The correlations were strongest with the Weissler index (ratio of pre-ejection and left-ventricular ejection times), PEP/LVET (r = -0.76; P less than 0.001), with PEP itself (r = -0.65; P less than 0.001), as well as with rate-corrected PEP (r = -0.71; P less than 0.001). The plain chest X-ray did not make it possible to assess quantitatively patients with diminished cardiac pump function, despite radiological signs of congestion. PMID:2354661

Schuster, P; Seiwert, F J; Neuhaus, C

1990-06-01

125

Condom use behaviours among 18-24 year-old urban African American males: a qualitative study  

PubMed Central

The purpose of this pilot project was to develop, administer and assess a brief male-focused and behavioural-driven condom promotion programme for young adult African American males in an urban setting. To achieve the aims of this study, linkages with local community centres were initially fostered and both quantitative and qualitative research methods were employed. Based on relevant tenets of the social cognitive theory and the stages of change model, a series of focus groups were conducted among the target population, recruited from non-traditional urban settings, to identify and further explore their perceived condom use barriers and facilitators in order to support programme development. Specifically, the topical items addressed those young men’s perceptions of sexuality and condom use within three broad contexts: general sexual behaviours, condom use behaviours, and the relationship between condoms and substance use. The focus group discussions were audiotaped and the transcribed data summarized and analysed based on those thematic topics. The findings revealed that significant myths, misconceptions and knowledge gaps exist regarding HIV/STD-related prevention, condom promotion and substance use. The findings imply that there is a critical need to develop target group suitable condom promotion programmes in order to successfully promote, foster and sustain condom use among high-risk populations.

KENNEDY, S. B.; NOLEN, S.; APPLEWHITE, J.; WAITERS, E.; VANDERHOFF, J.

2007-01-01

126

The surgical management of a leiomyosarcoma of the submandibular gland in a 95-year-old patient.  

PubMed

Primary sarcomas of the major salivary glands are rare and appear to originate from undifferentiated pluripotential mesenchymal cells. They must be distinguished from malignant supporting tissue neoplasms that secondarily involve the glands by direct extension or metastasis. Multidisciplinary management of head and neck soft tissue sarcomas is still controversial. We report a case of leiomyosarcoma of the submandibular gland in a 95-year-old man who was treated with excision of the right submandibular gland, extended to the surrounding tissues, without neck dissection. The patient tolerated the treatment well. Twenty-four months after surgery, the patient was doing well without any evidence of locoregional or distant disease. Surgery is the cornerstone of the management of leiomyosarcomas of the salivary glands. Wide surgical excision with histologically proven tumor-free margins was an appropriate treatment that may guarantee prolonged survival. PMID:21856190

Boffano, Paolo; Roccia, Fabio; Zavattero, Emanuele; Gallesio, Cesare; Cassarino, Emanuele; Campisi, Paola; Berrone, Sid

2011-08-19

127

Primary immunodeficiency in combination with transverse upper limb defect and anal atresia in a 34-year-old patient with Jacobsen syndrome.  

PubMed

We describe a 34-year-old male patient with Jacobsen syndrome associated with a broad spectrum of anomalies and an increased susceptibility to infections. Features commonly seen in Jacobsen syndrome were short stature, mental retardation, congenital heart disease, cryptorchidism, strabismus, distal hypospadia glandis, and mild thrombocytopenia. Chromosome analysis disclosed a mosaic 46,XY,del(11)(q24.1)/46,XY karyotype with a very low percentage of normal cells. In addition, transverse upper limb defect, imperforate anus, and hearing impairment were noted. Cellular anomalies include functional impairment and deficiency of T-helper cells, and a low serum immunoglobulin M (IgM)-level. The presence of a transverse limb defect and primary immunodeficiency has not been reported previously in Jacobsen syndrome. PMID:15054845

von Bubnoff, Dagmar; Kreiss-Nachtsheim, Martina; Novak, Natalija; Engels, Eva; Engels, Hartmut; Behrend, Claudia; Propping, Peter; de la Salle, Henri; Bieber, Thomas

2004-04-30

128

Secondary Chondrosarcoma of the Pelvis Arising from a Solitary Exostosis in an 11-Year-Old Patient  

PubMed Central

Although conversion of an osteochondroma to chondrosarcoma is a well-described rare occurrence, it is usually associated with syndromes such as multiple hereditary exostoses and is much more common after maturity. We present here a rare case of secondary pelvic chondrosarcoma arising from a solitary exostosis in a pediatric patient. An 11-year-old, otherwise healthy, female was referred to our clinic for evaluation of a pelvic mass detected on a radiograph. The radiographs obtained by the referring physician demonstrated a large lesion arising from the right superior pubic ramus, which was visible but not identified on an abdominal radiograph several years prior. Histopathologic analysis showed chondrosarcoma which was supported by an additional opinion to rule out chondroblastic osteosarcoma. The patient was treated with wide resection without adjuvant therapy and is doing well with no evidence of recurrence five years post-operatively. There have been only a few small case series describing chondrosarcoma in the pediatric patient. Even rarer are descriptions of secondary chondrosarcoma with only occasional cases reported as part of larger case series. Chondrosarcoma is a rare and difficult diagnosis in the pediatric patient. There is often considerable debate between chondrosarcoma and chondroblastic osteosarcoma, and the treatment implications of differentiating these diagnoses are of paramount importance.

Nystrom, Lukas M.; DeYoung, Barry R.; Morcuende, Jose A.

2013-01-01

129

Iatrogenic aspiration of a large piece of a wooden spoon in a 14-year-old epilepsy patient.  

PubMed

Foreign body aspiration in childhood is a common and life-threatening emergency. A 14-year-old male with history of mental retardation was transferred from another center to our hospital with diagnosis of foreign body aspiration. According to the anamnesis, he had been diagnosed with epilepsy a few years ago. Approximately 10 hours before admission, while at home, his parents had urgently placed a wooden spoon in the boy's mouth during a generalized tonic-clonic seizure to avoid possible airway injury. Nevertheless, he had inhaled a large piece of the wood after breaking the handle of the spoon with his teeth. Rigid bronchoscopic evaluation revealed the presence of a large piece of wood sitting vertically 2 cm beyond the glottis. Although bronchoscopic removal of the wooden piece from the trachea was difficult and prolonged, it was successful. Following this process, he presented with subcutaneous emphysema and pneumothorax in the intensive care unit (ICU). After improvement with the aid of chest tube drainage in the ICU, he was discharged from the hospital on the 3rd day of rigid bronchoscopy. Early diagnosis and urgent removal of a foreign body are very important for reducing mortality. However, complications related to the foreign body itself or the bronchoscopy may occur. In conclusion, the physical characteristics, position and location of the foreign body can influence the outcome, even in skilled hands. PMID:21935837

Sazak, Hilal; Yaz?c?, Ulkü; Gülgösteren, Mahmut; Topçuo?lu, Güler; Ozkan, Serdar; Savk?l?o?lu, Eser

2011-07-01

130

Efficacy and tolerability of EPs 7630 in patients (aged 6-18 years old) with acute bronchitis  

PubMed Central

Aim: For EPs-7630, a herbal drug preparation from Pelargonium sidoides roots, therapeutic effects in respiratory tract infections outside the strict indication for antibiotics have already been demonstrated in adults. Now, a dose-finding study for EPs-7630 was performed in children and adolescents. Methods: A total of 400 patients (aged 6–18 years) were randomized to receive either 30 mg, 60 mg or 90 mg EPs-7630 or placebo daily. Primary outcome criterion was the change in the Bronchitis Severity Score (BSS) from day 0 to day 7. Results: After 7 days of treatment, the change in the BSS total score was significantly better in the 60 mg and 90 mg groups compared with placebo that of the without relevant differences between these two dosages. Especially ‘coughing’, ‘sputum’ and ‘rales at auscultation’ improved under EPs-7630. Onset of effect was faster, time of bed rest shorter and treatment outcome and satisfaction with treatment were rated better. Tolerability was comparable with placebo in all treatment groups. Conclusion: EPs-7630 is effective in acute bronchitis outside the strict indication for antibiotics in 6–18 years old patients, with a dose of 60 mg or 90 mg daily offering the best benefit/risk ratio. EPs-7630 significantly reduces the severity of symptoms, leads to a more favourable course of the disease and a faster recovery from acute bronchitis compared with the placebo, and is well tolerated.

Kamin, W; Maydannik, VG; Malek, FA; Kieser, M

2010-01-01

131

Minimal change nephrotic syndrome in an 82 year old patient following a tetanus-diphteria-poliomyelitis-vaccination  

PubMed Central

Background The most common cause of idiopathic nephrotic syndrome in children and younger adults is the minimal change nephrotic syndrome (MCNS). In the elderly MCNS is relatively uncommon. Over the last decade some reports suggest a rare but possible association with the administration of various vaccines. Case presentation A 82-year old Caucasian female presented with pronounced nephrotic syndrome (proteinuria of 7.1 g/d, hypoproteinemia of 47 g/l). About six weeks prior to admission, she had received a combination vaccination for tetanus, diphtheria and poliomyelitis as a booster-vaccination from her general practitioner. The renal biopsy revealed typical minimal change lesions. She responded well to the initiated steroid treatment. As through physical examination as well as extensive laboratory and imaging studies did neither find any evidence for malignancies nor infections we suggest that the minimal change nephrotic syndrome in this patient might be related to the activation of the immune system triggered by the vaccination. Conclusion Our case as well as previous anecdotal reports suggests that vaccination and the resulting stimulations of the immune system might cause MCNS and other severe immune-reactions. Increased awareness in that regard might help to expand the database of those cases.

2009-01-01

132

A case of an 18-year-old male rugby union forward with a C5/C6 central disc herniation.  

PubMed

The patient was an 18-year-old front row forward rugby player who had a history of episodic neck pain for over 2 years following playing games of rugby. The initial event of April 2005 for which the symptoms manifested was a scrum collapse; he continued playing until a front-on tackle occurred when the symptoms dictated that he leave the field and be taken to the local hospital. A diagnosis of a cervical sprain was made and conservative management ensued. During the selections held on January 2008, a medical assessment was made and an MRI found that he had a central disc herniation at C5/C6. He was referred to a spinal orthopaedic surgeon for further treatment. The risks to cervical spinal injuries are illustrated in this case, in a scrum and in the tackle. The prevention of such an injury is discussed. PMID:21686741

Broughton, Henare Renata

2009-04-28

133

Blister-like supraclinoid internal carotid artery pseudoaneurysm in a 15-year-old male: case report and review of the literature.  

PubMed

With an incidence of less than 1-3 per million, pediatric aneurysms are rare clinical entities. A traumatic etiology is implicated in a large proportion of these cases, leading to the formation of both 'false' and 'true' aneurysms. These occur most often in the distal circulation, but have also been described in the supraclinoid distal internal carotid artery (ICA). Blood blister aneurysms are also found in this location; however, they have not been described in the pediatric population. We report the case of a 15-year-old male who presented following cranial trauma with diffuse basal subarachnoid hemorrhage and limited additional intracranial pathology. Computed tomography angiography demonstrated a small, 2-mm blister-like aneurysm arising from the dorsal surface of the left supraclinoid ICA at a non-branching site. Despite early endovascular treatment with Guglielmi detachable coils, the lesion continued to grow over subsequent studies, necessitating open surgical clipping. At the time of surgery, gross pathology of the native ICA was observed, raising the possibility of a preexisting blood-blister aneurysm. We review the epidemiology, pathophysiology and diagnostic considerations of these lesions. The endovascular and surgical management of these complex non-branching supraclinoid ICA aneurysms is also discussed. PMID:22777210

Haji, Faizal Aminmohamed; Boulton, Melfort R; de Ribaupierre, Sandrine

2012-07-07

134

Robot-assisted laparoscopic prostatectomy in a 68-year-old patient with previous heart transplantation and pelvic irradiation  

Microsoft Academic Search

We report the case of a 68-year-old man who had previously undergone heart transplantation and pelvic irradiation for Hodgkin’s\\u000a lymphoma and who was under active surveillance for prostate cancer. In response to his increased prostate-specific antigen\\u000a levels and elevated Gleason score, he was offered robot-assisted laparoscopic prostatectomy.

Karol Axcrona; Ljiljana Vlatkovic; Jarl Hovland; Bjørn Brennhovd; Ulf Kongsgaard; Karl-Erik Giercksky

135

Unusually long survival of a 67-year-old patient with near-tetraploid acute myeloid leukemia m0 without erythroblastic and megakaryocytic dysplasia.  

PubMed

Patients with near-tetraploid acute myeloid leukemia (NT-AML) typically have poor survival. We present the case of a 67-year-old Caucasian male with NT-AML M0 who had an unusually long first complete remission of 51 months and an overall survival of 80 months. The only characteristic distinguishing him from other previously described patients with NT-AML was the absence of erythroblastic and/or megakaryocytic dysplasia (EMD) at diagnosis. Molecular-genetic testing for AML fusion transcripts associated with a favorable prognosis (PML/RAR?,AML1/ETO, and CBF?/MYH11) were negative, as were other prognostic markers like MLL-PTD,FLT3-ITD, or mutations of FLT3-D835,NPM1, or CEBPA. Expression studies of ERG,MN1, and EVI1 revealed overexpression of ERG only. The absence of EMD may be a useful prognostic/diagnostic feature of this new rare subtype of NT-AML. PMID:21701158

Lemež, Petr; Klamová, Hana; Zemanová, Zuzana; Marinov, Iuri; Fuchs, Ota; Schwarz, Ji?í; B?ezinová, Jana; Provazníková, Dana; Koste?ka, Arnošt; Marková, Jana; Michalová, Kyra; Jelínek, Jaroslav

2011-06-24

136

Bilateral Optic Nerve Sheath Meningioma with Intracanalicular and Intracranial Component in a 25-year-old Saudi Patient  

PubMed Central

Bilateral optic nerve sheath meningioma is rare. A meningioma is a benign neoplastic lesion from meningothelial cells of the meninges. They usually involve the intracanalicular portion of the optic nerve but may extend into the optic canal and through it to occupy the intracranial space. We present a case of 25-year-old Saudi female with bilateral optic nerve sheath meningioma. The diagnosis was delayed more than six years from initial symptoms.

Badr, Maha A.; Elkhamary, Sahar M.; Al Sabbagh, Samira; Al Turjoman, Abdulsalam

2008-01-01

137

Effect of Postmastectomy Radiotherapy in Patients <35 Years Old With Stage II-III Breast Cancer Treated With Doxorubicin-Based Neoadjuvant Chemotherapy and Mastectomy  

SciTech Connect

Purpose: Postmastectomy radiotherapy (PMRT) improves locoregional control (LRC) in patients with high-risk features after mastectomy. Young age continues to evolve as a potentially important risk factor. The objective of this study was to assess the benefits of PMRT in patients <35 years old treated with doxorubicin-based neoadjuvant chemotherapy for Stage II-III breast cancer. Patients and Methods: We retrospectively analyzed 107 consecutive breast cancer patients <35 years old with Stage IIA-IIIC disease treated at our institution with doxorubicin-based neoadjuvant chemotherapy and mastectomy, with or without PMRT. The treatment groups were compared in terms of LRC and overall survival. Results: Despite more advanced disease stages, the patients who received PMRT (n = 80) had greater rates of LRC (5-year rate, 88% vs. 63%, p = 0.001) and better overall survival (5-year rate, 67% vs. 48%, p = 0.03) than patients who did not receive PMRT (n = 27). Conclusion: Among breast cancer patients <35 years old at diagnosis, the use of PMRT after doxorubicin-based neoadjuvant chemotherapy and mastectomy led to a statistically greater rate of LRC and overall survival compared with patients without PMRT. The benefit seen for PMRT in young patients provides valuable data to better tailor adjuvant, age-specific treatment decisions after mastectomy.

Garg, Amit K. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Oh, Julia L. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)], E-mail: joh@mdanderson.org; Oswald, Mary Jane; Huang, Eugene; Strom, Eric A.; Perkins, George H.; Woodward, Wendy A.; Yu, T. Kuan; Tereffe, Welela [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Meric-Bernstam, Funda [Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Hahn, Karin [Department of Breast Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Buchholz, Thomas A. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)

2007-12-01

138

Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes  

Microsoft Academic Search

Aims\\/hypothesis  We investigated whether there was evidence of attempted beta cell regeneration in the pancreas obtained from a patient with recent-onset type 1 diabetes, and if so by what mechanism this occurred.Subjects, materials and methods  We examined pancreas tissue from a lean 89-year-old patient (BMI 18.0 kg\\/m2) with recent-onset type 1 diabetes who had had a distal pancreatectomy to remove a low-grade pancreatic

J. J. Meier; J. C. Lin; A. E. Butler; R. Galasso; D. S. Martinez; P. C. Butler

2006-01-01

139

A 5YearOld Boy with Cryptorchidism and Pubic Hair: Investigation and Management of Apparent Male Disorders of Sex Development in Mid-Childhood  

Microsoft Academic Search

Background: Late presentation of congenital adrenal hyperplasia as a 46,XX disorder of sex development due to 11-? hydroxylase deficiency is uncommon. Such a case raises issues regarding appropriate investigation and management. Case History: A 5-year-old boy who had recently moved to the United Kingdom presented at the endocrinology clinic with recurrent abdominal pain. He was normotensive and had a history

L. S. Keir; S. O’Toole; A. L. Robertson; A. M. Wallace; S. F. Ahmed

2009-01-01

140

Fatality Assessment and Control Evaluation (FACE) Report for Kentucky: 21 Year-Old Male Dies When Struck in the Head with a Track Hoe Bucket, FACE-02-KY-106.  

National Technical Information Service (NTIS)

On November 22, 2002, a 21-year-old male laborer died after being hit in the head with the bucket of a track hoe. He was wearing a safety helmet at the time of the incident. There were six to seven workers at the job site when the incident occurred. The w...

2003-01-01

141

Brief Communication Recurrent pulmonary embolism in a 13-year-old male homozygous for the prothrombin G20210A mutation combined with protein S deficiency and increased lipoprotein (a)  

Microsoft Academic Search

We report the case of a 13-year-old male presenting with recurrent symptoms of respiratory distress after a trauma of the lower limb. Pulmonary symptoms had been misinterpreted for several weeks and only marked symptoms of deep venous (DVT) and caval vein thrombosis later prompted the correct diagnosis of DVT and embolic events and subsequently a successful thrombolytic therapy. The case

Andrea Kosch; Ralf Junker; Cornelia Wermes; Ulrike Nowak-Gottl

142

Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial  

PubMed Central

Background An aging population and better management of various heart diseases explain the exponential growth in incidence and prevalence of chronic heart failure, with poor prognosis and heavy health costs. Medical management is codified in international guidelines. The management of heart failure in over-80 year-old patients follows these guidelines, but no clinical trials have been able to confirm benefit. Moreover, registries show down-prescription of heart failure treatments in the elderly and over-80s. Methods/Design We present the design of the HF-80 ("Is there benefit in optimising heart failure treatment in over-80 year-old patients?") study, which is a prospective randomised open-label clinical trial with blinded end-points, designed to evaluate the effect of optimising management by adhering to guidelines in over-80 year-old heart failure patients. Patients over 80 years of age admitted with acute heart failure will be included. The primary endpoint is to assess quality of life at 6 months on the Minnesota questionnaire. The secondary endpoints are to assess the effect of optimised management on quality of life, mortality, readmission for acute heart failure, cardiac fibrosis and economic data at 12 months. 80 patients will be included, divided into 2 groups: group A, with usual heart failure management by general practitioners; and group B, with optimised management based on international guidelines. Discussion It is necessary to assess the benefit of guidelines in over-80 year-old heart failure patients because of the fragility of this population and the elevated risk of iatrogenic complications. Trial Registration Clinical trials.gov number: NCT01437371.

2012-01-01

143

Breast cancer detection method among 20- to 49-year-old patients at a community based cancer center: 1990-2008.  

PubMed

Our research goal is to report on method of breast cancer detection among young women from a prospective cohort study of primary breast cancer patients, aged 20-49?years, 1990-2008 (n?=?2579). Clinical presentation characteristics including race, TNM stage, first degree relative family history, histologic type and method of detection by patient (PtD), physician (PhysD), or mammography (MamD) were chart abstracted. Forward conditional stepwise regression was used to for association with detection method and Kaplan-Meier for relapse free survival (RFS) analysis. Among 20- to 39-year olds (n?=?602) no change in detection method occurred over time with 12% MamD, 7% PhysD, and 81% PtD. Among 40- to 49-year olds, MamD BC increased over time (28% to 58%) and PtD BC decreased (63-36%) (Pearson X(2) =?72.72, p?year old MamD cases 31%/32% were stage 0 versus 2%/6% of the PhysD/PtD cases. In two separate conditional logistic regression models, older age at diagnosis and first degree relative BC history were associated with MamD BC for 20- to 39- and 40- to 49-year olds. Five-year MamD BC RFS was superior for both age groups (20-39: 94%, 40-49: 94%) compared to PtD BC rates (20-39: 80%, p?=?.016; 40-49: 88%, p?year olds had worse RFS (5?year 80%, 10?year 75%) than 40- to 49-year olds (5?year 88%, 10?year 82%) (p?=?.002) but RFS was equivalent for MamD cases by age. The majority of breast cancers among women 20-49?years were patient detected and mammography detection occurred rarely among youngest women. Lower stage and superior survival among MamD patients support mammography for detecting disease in high risk women aged 30-39?years and 40-49?years. PMID:22487162

Malmgren, Judith; Atwood, Mary; Kaplan, Henry

2012-04-05

144

Late-onset combined immune deficiency associated to skin granuloma due to heterozygous compound mutations in RAG1 gene in a 14 years old male.  

PubMed

We report a male with atypical severe combined immunodeficiency caused by heterozygous compound mutations c.256-257del and c.C1331T in RAG1 gene. The patient presents with recurrent bronchopneumonias with obstruction, chronic fibrosing alveolitis, complicated by respiratory failure, pulmonary hypertension and hepatosplenomegaly. He was diagnosed with agammaglobulinemia at the age of 9. His condition was complicated by granulomatous skin disease at the age of 12 despite regular IVIg substitution. Immunological presentation included profound hypogammaglobulinemia and absence of B cells. Under immunoglobulin substitution for 5 years patient has permanent lymphopenia, skewed phenotype of T cells and diminished number of recent thymic emigrants. PMID:23085344

Sharapova, Svetlana O; Migas, Alexandr; Guryanova, Irina; Aleshkevich, Svetlana; Kletski, Semen; Durandy, Anne; Belevtsev, Michael

2012-10-17

145

Identification of an unusual Brucella strain (BO2) from a lung biopsy in a 52 year-old patient with chronic destructive pneumonia  

Microsoft Academic Search

BACKGROUND: Brucellosis is primarily a zoonotic disease caused by Brucella species. There are currently ten Brucella spp. including the recently identified novel B. inopinata sp. isolated from a wound associated with a breast implant infection. In this study we report on the identification of an unusual Brucella-like strain (BO2) isolated from a lung biopsy in a 52-year-old patient in Australia

Rebekah V Tiller; Jay E Gee; David R Lonsway; Sonali Gribble; Scott C Bell; Amy V Jennison; John Bates; Chris Coulter; Alex R Hoffmaster; Barun K De

2010-01-01

146

Pain Reporting, Opiate Dosing, and the Adverse Effects of Opiates After Hip or Knee Replacement in Patients 60 Years Old or Older  

PubMed Central

Our goal was to determine whether there were age-related differences in pain, opiate use, and opiate side effects after total hip or knee arthroplasty in patients 60 years old or older. We hypothesized that there would be no significant differences between age groups in (1) mean pain score, (2) opiate use after adjusting for pain, or (3) opiate side effects after adjusting for opiate use and pain score. We retrospectively reviewed the electronic and paper charts of all patients undergoing total joint replacements at our institution over 3 years who met the following criteria: (1) 60 years old or older, (2) primary single total knee or total hip replacement, and (3) no preoperative dementia. Preoperative, intraoperative, and postoperative course data were collected using a customized data entry process and database. We divided the patients into 2 age groups, those 60 to 79 years old and those 80 years old or older. Using a marginal model with the panel variable of postoperative day, we investigated the associations between age group and pain, age group and pain adjusting for opiate use, and age group and complications (respiratory depression, naloxone usage as a measure of respiratory arrest, delirium, constipation, and urinary retention) adjusting for opiate use (Xtgee, Stata10, Stata Corp. LP, College Station, Texas). Significance was set at P < .05. We found no significant difference in pain scores between groups, but the older group had significantly fewer opiates prescribed yet significantly more side effects, including delirium (odds ratio 4.2), than did the younger group, even after adjusting for opiate dose and pain score.

Petre, Benjamin M.; Roxbury, Christopher R.; McCallum, Jeremy R.; DeFontes, Kenneth W.; Belkoff, Stephen M.; Mears, Simon C.

2012-01-01

147

Successful treatment with low-dose decitabine in acute myelogenous leukemia in elderly patients over 80 years old: Five case reports  

PubMed Central

The incidence of acute myelogenous leukemia (AML) in patients over 80 years old is >20 times greater than that observed in younger patients. Previously, no standard treatment protocol for elderly patients with AML existed, however the development of hypomethylating agents, including decitabine, has brought about promising results in AML. In the present study, we report on the usage of a lower than routine dosage of decitabine in patients over 80 years old with AML. Since January 2010, 5 patients diagnosed with AML over the age of 80 years old received treatment with decitabine in our hospital. Decitabine was administered at a dose of 10–15 mg/m2 and repeated every other day for a total of 5 days. This cycle was repeated for ?6 weeks. The 5 patients received a total of 19 cycles of treatment with decitabine. No patient achieved complete or partial remission. An antileukemic effect was observed in 25% of courses (3/12). An increase in platelet count of >20×109/l was observed in 26.3% (5/19) of cycles compared with previous treatment. An increase in hemoglobin concentration of >20 g/l was observed in 36.8% (7/19) of cycles in comparison to previous treatment, four of which achieved normal hemoglobin levels. One patient became red blood cell transfusion-independent. The median survival time was 19.8±4.8 months. Survival time from decitabine administration to mortality was 13.2±5.1 months. The main side-effect was bone marrow suppression with grade III–IV thrombocytopenia, grade III–IV leukocytopenia, grade III–IV neutropenia and anemia accounting for 94.7% (18/19), 47.4% (9/19), 89.5% (17/19) and 21.1% (4/19), respectively. Severe infection or bleeding was not observed and no patient stopped treatment due to adverse effects. In conclusion, extremely low-dose decitabine may be used safely in elderly patients and achieved longer survival times than reported previously in AML patients aged 80 and above. It is suggested that complete remission may not be the primary objective, while improvement of quality of life may be a better choice in AML patients over 80 years old. The cases observed in our study were limited, so more cases are required for further study.

LIN, JIE; ZHU, HONGLI; LI, SUXIA; FAN, HUI; LU, XUECHUN; CHANG, CHENG; GUO, BO; ZHAI, BING

2013-01-01

148

Severe frostbite injury in a 19-year-old patient requiring amputation of both distal forearms and lower legs due to delayed rescue: a need for advanced accident collision notification systems?  

PubMed

Frostbite injury is a rare but severe injury especially when rescue triage is prolonged. We here report the case of a 19-year-old male patient with severe frostbite injuries requiring amputation of both distal forearms and both lower legs due to delayed admission to medical care. This case demonstrates that even mild ambient temperatures can cause deleterious injuries if the exposure time is long enough paralleling our knowledge of burn trauma. Immediate admission to medical care is, therefore, paramount and GPS-based automated accident collision notification systems would therefore be of great benefit especially in rural areas. PMID:21298278

Kloeters, Oliver; Ryssel, Henning; Suda, Arnold J; Lehnhardt, Marcus

2011-02-05

149

FH Tulsa-1 and -2: Two unique alleles for familial hypercholesterolemia presenting in an affected two-year-old African-American male  

SciTech Connect

A two-year-old African American boy presented with cutaneous xanthomata and extreme hypercholesterolemia. Subsequent studies revealed that the LDL-cholesterol was 1,001 mg/dl and apoB 507 mg/dl. LDL-receptor activity was almost undetectable, which is compatible with the finding of two newly described defective alleles on exon 4 of the LDL-receptor gene coding for part of the ligand-binding domain. One allele contained a 21 base-pair insertion from codon 200 to 207 whereas the other had a point mutation at codon 207. The rarity of genes for FH reported in individuals of African ancestry is discussed. 16 refs., 2 figs., 2 tabs.

Blackett, P.R.; Altmiller, D.H. [Univ. of Oklahoma Health Services Center, Oklahoma City, OK (United States); Jelley, D. [Childrens Medical Center, Tulsa, OK (United States); Wilson, D.P. [Driscoll Children`s Hospital, Corpus Christi, TX (United States)

1995-11-20

150

Multimodal endovascular management of acute ischemic stroke in patients over 75 years old is safe and effective  

PubMed Central

Introduction Greater attention has been directed to endovascular recanalization of acute ischemic stroke in septuagenarians and above. Technique A retrospective chart review was conducted to include patients treated for acute ischemic stroke from 2006 to 2012. All patients underwent initial neurological assessment and non-contrast head CT. Patients treated from 2009 to 2012 additionally received emergent CT angiogram and CT perfusion. 51 patients met the clinical and radiographic criteria and underwent multimodal endovascular revascularization for acute ischemic events. Results All patients underwent cerebral angiography and met angiographic criteria for endovascular thrombolysis. 34 patients (67%) were older than 80?years of age. 23 patients (45%) received intravenous tissue plasminogen activator prior to admission. Eight (16%) patients underwent stent placement after intra-arterial thrombolysis, 10 (20%) underwent balloon angioplasty and seven (14%) underwent both angioplasty and stent placement. 21 (41%) required only intra-arterial thrombolytics. An improvement in Thrombolysis in Myocardial Infarction score was noted in 34 patients (67%). The average modified Rankin Scale score on discharge was 3.9. Symptomatic intracranial hemorrhage occurred in three patients (6%); none required surgery. One patient (1.9%) had a postoperative retroperitoneal hematoma, which was managed conservatively. Two fatalities resulted from intraoperative vessel rupture (3.9%), with a combined morbidity and mortality of 27.5%. Conclusions Multimodal endovascular recanalization of acute ischemic stroke is a relatively safe treatment option in patients older than 75?years of age. Careful patient selection by clinical and radiographic inclusion criteria is necessary for the successful management of stroke in this age group.

Ghobrial, George M; Chalouhi, Nohra; Rivers, Lana; Witte, Samantha; Davanzo, Justin; Dalyai, Richard; Gardecki, Michelle L; Jabbour, Pascal; Gonzalez, Fernando; Dumont, Aaron S; Rosenwasser, Robert H; Tjoumakaris, Stavropoula

2013-01-01

151

Phakic intraocular lens implantation versus clear lens extraction in highly myopic eyes of 30- to 50-year-old patients  

Microsoft Academic Search

Purpose: To compare the outcome of treatment for myopia by phakic intraocular lens (IOL) implantation or by clear lens extraction (CLE).Setting: Service d'Ophtalmologie, Hôpital Purpan, Toulouse, France.Methods: Thirty-nine patients from 32 to 49 years of age were studied. Forty-one eyes of 21 patients received a phakic IOL, and 36 eyes of 18 patients had phacoemulsification of the crystalline lens. The

Jean L. Arne

2004-01-01

152

A Novel Deletion Mutation of SLC16A2 Encoding Monocarboxylate Transporter (MCT) 8 in a 26-year-old Japanese Patient with Allan-Herndon-Dudley Syndrome.  

PubMed

Allan-Herndon-Dudley Syndrome (AHDS), an X linked condition, is characterized by congenital hypotonia that progresses to spasticity with severe psychomotor delays, in combination with altered thyroid hormone levels, in particular, high serum T3 levels. Recently, this disease was proved to be caused by mutations in SLC16A2 coding for the monocarboxylate thyroid hormone transporter 8 (MCT8). Here we describe a 26-year -old Japanese patient with AHDS who had deletion of exon 3 of SLC16A2. PMID:24170966

Yamamoto, Sayaka; Okuhara, Koji; Tonoki, Hidefumi; Iizuka, Susumu; Nihei, Noriko; Tajima, Toshihiro

2013-10-26

153

A Novel Deletion Mutation of SLC16A2 Encoding Monocarboxylate Transporter (MCT) 8 in a 26-year-old Japanese Patient with Allan-Herndon-Dudley Syndrome  

PubMed Central

Abstract. Allan-Herndon-Dudley Syndrome (AHDS), an X linked condition, is characterized by congenital hypotonia that progresses to spasticity with severe psychomotor delays, in combination with altered thyroid hormone levels, in particular, high serum T3 levels. Recently, this disease was proved to be caused by mutations in SLC16A2 coding for the monocarboxylate thyroid hormone transporter 8 (MCT8). Here we describe a 26-year -old Japanese patient with AHDS who had deletion of exon 3 of SLC16A2.

Yamamoto, Sayaka; Okuhara, Koji; Tonoki, Hidefumi; Iizuka, Susumu; Nihei, Noriko; Tajima, Toshihiro

2013-01-01

154

Eruptive Nevi Mimicking Wart-Like Lesions under Selective BRAF Inhibition in a 37-Year-Old Female Melanoma Patient  

PubMed Central

Background The BRAF inhibitor vemurafenib is state of the art in therapy of patients with malignant melanoma in non-resectable stage III or stage IV and evidence of oncogenetic BRAF mutation. Multiple cutaneous side effects like rash and keratoacanthoma-like lesions have been described so far. Case Report We report a patient who presented multiple wart-like lesions under therapy with vemurafenib. Histologically we have seen multiple melanocytic nevi with a wart-like appearance. One melanoma in situ developed on the left forearm. Conclusions Eruptive nevi and induction of melanoma may be a further side effect in patients undergoing a therapy with BRAF inhibitors.

Schmitt, Laurenz; Schumann, Tamara; Inhoff, Oliver; Loser, Christoph; Rebel, Martin; Dippel, Edgar

2013-01-01

155

Primary Hyperoxaluria Type 1 Causing End-Stage Renal Disease in a 45YearOld Patient  

Microsoft Academic Search

Primary hyperoxaluria type 1 (PH1) is caused by deficiency of peroxisomal alanine-glyoxylate aminotransferase which is in humans exclusively expressed in liver cells. The disease is inherited as an autosomal recessive trait, and initial symptoms usually occur in early childhood. Up to the age of 25 years, 90% of the patients are symptomatic, and many patients develop end-stage renal failure. Pronounced

T. David-Walek; C. Niederstadt; P. M. Rob; L. Fricke; K. Latta; J. Steinhoff; E. F. Stange

2001-01-01

156

Aggressive treatment is appropriate for glioblastoma multiforme patients 70 years old or older: a retrospective review of 206 cases*  

PubMed Central

Elderly patients have largely been excluded from randomized trials for glioblastoma multiforme (GBM). We reviewed the results of treatment approaches, which included surgery, chemotherapy, and radiation in this group of patients. Patients were treated during the period 1979–2007 and were 70 years of age and older with histologically confirmed GBM. Overall survival (OS) was the primary endpoint of this retrospective study. Two hundred six patients 70 years of age and older were identified. Median age was 75 years (range 70–90). Median OS time was 4.5 months. Univariate analysis showed that OS was significantly impacted by KPS score (1.8 months for KPS ?50 to 17.2 months for KPS ?90, P < .001), age at diagnosis (5.1 months for age 70–79 versus 3.1 months for age ?80, P < .001), and extent of disease (worse for bilateral disease [P = .003], multifocal disease [P = .005], and multicentric disease [P = .02]). On multivariate analysis, higher KPS score (P = .006), surgical resection (any surgery beyond biopsy) (P < .001), radiation therapy (P < .001), and chemotherapy (P < .001) were all found to be independently associated with improved OS. In this study of newly diagnosed glioblastoma patients over the age of 70 years, aggressive treatment with radiation, chemotherapy, and surgery is associated with OS.

Scott, Jacob G.; Suh, John H.; Elson, Paul; Barnett, Gene H.; Vogelbaum, Michael A.; Peereboom, David M.; Stevens, Gene H. J.; Elinzano, Heinrich; Chao, Samuel T.

2011-01-01

157

[Sucessful treatment with clofazimine and itraconazole in a 46 year old patient after 32 years duration of disease].  

PubMed

Lobomycosis, caused by the fungal pathogen Lacazia loboi, is a chronic deep mycosis and is only found in Central and South America. Clinically the disease is characterized by shiny keloidal nodules appearing mainly on the exposed parts such as face and the upper and lower extremities. Therapeutically the surgical removal of the lesions is considered as the only successful treatment. We describe the therapeutic response of a patient with Lobo's disease treated for one year with a combination of clofazimine (100 mg/day) and itraconazole (100 mg/day). A complete clinical and histopathological remission of the disease was observed. The patient has been followed for three years. PMID:12297950

Fischer, M; Chrusciak Talhari, A; Reinel, D; Talhari, S

2002-10-01

158

Prosthetic reconstruction using gingiva-colored ceramic agent in fixed partial restoration in a 24-year old patient.  

PubMed

Achieving an optimal esthetic result when replacing missing anterior teeth with a fixed partial denture can be a challenge. This is especially true when interdisciplinary treatment is needed and the patient refuses this for personal or financial reasons. Here we report a clinical case where a fixed partial denture was used to change the incisor relationship and to restore the normal tooth and gingival tissue shape, morphology, and relationship by including artificial gingiva within the fixed partial denture when the patient refused lengthy and costly multispecialty treatment options. PMID:23674924

Sadaqah, Nasrin R; Tair, Jawad Ali Abu

2012-11-30

159

Prosthetic reconstruction using gingiva-colored ceramic agent in fixed partial restoration in a 24-year old patient  

PubMed Central

Achieving an optimal esthetic result when replacing missing anterior teeth with a fixed partial denture can be a challenge. This is especially true when interdisciplinary treatment is needed and the patient refuses this for personal or financial reasons. Here we report a clinical case where a fixed partial denture was used to change the incisor relationship and to restore the normal tooth and gingival tissue shape, morphology, and relationship by including artificial gingiva within the fixed partial denture when the patient refused lengthy and costly multispecialty treatment options.

Sadaqah, Nasrin R; Tair, Jawad Ali Abu

2012-01-01

160

Astrocytoma development following complete multiple myeloma remission in a 49-year-old patient: A case report  

PubMed Central

Multiple myeloma (MM), one of the B-cell non-Hodgkin lymphomas, is a bone marrow-derived, antibody-producing cancer of the plasma cells. In the advanced stages, the cancer cells frequently cause widespread osteolytic bone damage; however, in rare cases, MM also manifests as an intracranial plasmacytoma. In the present study, we describe a case in which a patient, initially treated for MM and with subsequent complete remission, was admitted to hospital with a lesion in the right cerebellar hemisphere and neurological symptoms of a brain tumor. Our initial diagnosis was an MM relapse with the rare occurring intracranial manifestation. However, pathological tests confirmed the diagnosis of a high-grade astrocytoma. In this case report, we describe the characteristics, as well as the treatment issues, diagnoses and clinical developments of this patient.

HAN, XIAOYAN; JIN, DIAN; ZHENG, GAOFENG; LUO, YI; CAI, ZHEN

2013-01-01

161

Prevalence and Impact of Anxiety and Depression on Type 2 Diabetes in Tunisian Patients over Sixty Years Old  

PubMed Central

Objectives. To estimate the prevalence of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS) in a population aged over sixty years with type 2 diabetes and to study the impact of anxiety and depression on glycemic balance and disease outcome. Results. The prevalence of anxiety and depression in the 62 subjects included in the study was, respectively, 40.3% and 22.6%. We found a relationship between these disorders and complicated diabetes. The subjects having an imperfectly balanced diabetes had a higher average anxiety score than those having a good glycemic control (9.1 ± 4.2 versus 6.5 ± 3.1; P = 0.017). No relationship was found between diabetes balance and depression. Conclusion. Association between anxiety and depressive disorders and diabetes is frequent and worsens patients' outcome, in terms of diabetes imbalance as well as in terms of diabetic complications. Our study shows that there is need for physicians to detect, confirm, and treat anxiety and depressive disorders in elderly diabetic patients.

Masmoudi, Jawaher; Damak, Rahma; Zouari, Hela; Ouali, Uta; Mechri, Anouar; Zouari, Nouri; Jaoua, Abdelaziz

2013-01-01

162

Human papillomavirus vaccine uptake among 9-17 year old males in the United States: The National Health Interview Survey, 2010.  

PubMed

In 2009, a quadrivalent HPV vaccine was approved and "permissively" recommended for US males aged 9 to 26 y to protect against genital warts. The purpose of this study was to examine parental awareness and HPV vaccine uptake among 9-17 y old males during the first year following this recommendation. Data from the 2010 National Health Interview Survey (NHIS) were obtained to assess vaccination status (n = 2973) of this age group. Univariate logistic regression analysis was performed to examine correlates of parental awareness and uptake of the HPV vaccine. Overall, 55% of parents with sons were aware of the HPV vaccine. The likelihood of parental awareness was lower among minorities and adolescents with low family incomes, and higher among adolescents with insurance, higher parental education, and those who had a well-child check up and dental examination in the past year than their counterparts. Only 2.0% and 0.5% of 9-17 y old males initiated (? 1 dose) and completed (? 3 doses) the vaccine series, respectively. Adolescents with a Hispanic origin (odds ratio (OR) 2.03, 95% confidence interval (CI) 1.09-3.78), low family income (OR 2.89, 95% CI 1.48 -5.57), and history of influenza vaccination in the past year (OR 1.89, 95% CI 1.11 -3.22) were more likely than their counterparts to initiate the HPV vaccine. On the other hand, adolescents with private insurance (OR 0.44, 95% CI 0.20 -0.94) and those who had college educated parents (OR 0.45, 95% CI 0.22 -0.89) were less likely to initiate the vaccine. This study showed that very few adolescent males received any doses of HPV vaccine during the first year following its recommendation for this gender. Thus, interventional programs are needed to improve vaccine uptake among adolescent males. PMID:23295743

Laz, Tabassum H; Rahman, Mahbubur; Berenson, Abbey B

2013-01-07

163

Meta-analysis comparing total hip arthroplasty with hemiarthroplasty in the treatment of displaced femoral neck fractures in patients over 70 years old.  

PubMed

Objective: Total hip arthroplasty (THA) and hemiarthroplasty (HA) are effective methods currently used to treat femoral neck fracture in elderly patients, but the two options remain controversial in patients over 70 years old. The main purpose of our study was to determine whether THA or HA is a superior treatment of femoral fractures involving a displaced neck in patients who are over 70 years of age. Methods: A computer-based online search of Medline (1970-2011), PubMed (1977-2011), and the Cochrane Central Register of Controlled Trials (2002-2011) was conducted. Six relevant randomized controlled trials with a total of 739 patients were included for the final analysis. The analysis was performed with software RevMan 5.0. Results: We found that compared with THA, HA needed shorter average time and lost less blood. While over the long-term follow-up, THA patients exhibited significantly less pain and better function and were less likely to require a revision hip surgery. Postoperative infection was equally common among HA and THA patients. Conclusions: The significant differences in outcomes suggest that THA is a valuable treatment option for active elderly hip fracture individuals. However, patients who are older, impaired or institutionalized benefit from HA. PMID:22863335

He, Jun-Hui; Zhou, Cheng-Pei; Zhou, Zong-Ke; Shen, Bin; Yang, Jing; Kang, Peng-de; Pei, Fu-Xing

2012-08-01

164

Childhood and adolescent body fat and its relationship with health outcome in 50 year old males and females: the Wroc?aw Growth Study.  

PubMed

The aim of the study was to estimate the association between relative weight in childhood and adolescence and its relationship with adult health outcome. Longitudinal data of the body mass index (BMI) from the Wroc?aw Growth Study (WGS) covering ages 8 to 18 and then a follow-up at 50 were used. At the age of 50, 124 males and 139 females in the longitudinal study underwent medical examination. Systolic and diastolic blood pressure (SBP, DBP), total cholesterol (TCH), high density lipoprotein cholesterol level (HDL), low density lipoprotein cholesterol level (LDL), triglyceride level (TGL) and fasting glucose level (GLUC) were assessed by using standard techniques. The values of BMI were standardised with the LMS method. Multiple linear regression was used to assess the relationship between health parameters and BMI at ages 8-18, adjusted for BMI at the age of 50, separately for different age categories and parameters, except for blood pressure where the usage of anti-hypertension medication was additionally used as a control variable. In males total cholesterol concentration showed a significant negative correlation with standardised BMI at ages 9-12 and 16 and 17. In females, only blood pressure showed a significant negative relationship with standardised BMI in all age categories reaching the highest values at age 15. The BMI in childhood and adolescence have only a weak effect on health outcome at age 50. PMID:21761602

Kozie?, S?awomir; Lipowicz, Anna; Hulanicka, Barbara

2011-06-01

165

Unintended Harm and Benefit of the Implantable Defibrillator in an Unfortunate 19-Year-Old Male: Featuring a Sequence of Rare Life-threatening Complications of Cardiac Procedures  

PubMed Central

All procedures have inherent risk. Our patient endured a sequence of rare life-threatening complications from commonly preformed procedures. The sequence of these complications was; large pericardial effusion post implantable cardioverter-defibrillator (ICD) implantation with echocardiographic signs of tamponade, left main narrowing post radiofrequency ablation, and late stent thrombosis post coronary intervention with a bare metal stent. All these occurred to one unfortunate young man. Furthermore, our patient demonstrated an unintended benefit of ICD which saved his life.

Daoulah, Amin; Ocheltree, Ali; Lotfi, Amir; Ocheltree, Sara; Alsheikh-Ali, Alawi A; Al-Habib, Abdul-Karim; El-Sayed, Osama; Haneef, Ali

2013-01-01

166

Secondary chondrosarcoma of the pelvis arising from a solitary exostosis in an 11-year-old patient: a case report with 5-year follow-up.  

PubMed

Although conversion of an osteochondroma to chondrosarcoma is a well-described rare occurrence, it is usually associated with syndromes such as multiple hereditary exostoses and is much more common after maturity. We present here a rare case of secondary pelvic chondrosarcoma arising from a solitary exostosis in a pediatric patient. An 11-year-old, otherwise healthy, female was referred to our clinic for evaluation of a pelvic mass detected on a radiograph. The radiographs obtained by the referring physician demonstrated a large lesion arising from the right superior pubic ramus, which was visible but not identified on an abdominal radiograph several years prior. Histopathologic analysis showed chondrosarcoma which was supported by an additional opinion to rule out chondroblastic osteosarcoma. The patient was treated with wide resection without adjuvant therapy and is doing well with no evidence of recurrence five years post-operatively. There have been only a few small case series describing chondrosarcoma in the pediatric patient. Even rarer are descriptions of secondary chondrosarcoma with only occasional cases reported as part of larger case series. Chondrosarcoma is a rare and difficult diagnosis in the pediatric patient. There is often considerable debate between chondrosarcoma and chondroblastic osteosarcoma, and the treatment implications of differentiating these diagnoses are of paramount importance. PMID:24027486

Nystrom, Lukas M; Deyoung, Barry R; Morcuende, Jose A

2013-01-01

167

Anaplastic large cell anaplastic lymphoma kinase + non-Hodgkin lymphoma in a 10-year-old male discovered during dental visit: a case report.  

PubMed

Non-Hodgkin lymphoma is rare in children, even though it is the third most frequent type of tumour. Management of a child with non-Hodgkin lymphoma is complex and coordinate presence of haematologists, surgeons, radiotherapists, neurologists, psychologists and other expert personnel is required. Our patient presented with a bulky mass of approximately 5 cm in diameter, which grew from his upper-left maxillary bone, thereby causing gum bulge. Thus, the left side of his face from lip to eye appeared swollen. A whole body computed tomography-positron emission tomography examination revealed that the mass was growing in the mouth and maxillary bone and that many bulky nodes were present both in the right and left neck. Histological haematoxylin and eosin assessment revealed an anaplastic large cell proliferation underlying the epithelial tissue without epithelial infiltration. The patient underwent a first cycle of chemotherapy according to the 'International Protocol of anaplastic large cell lymphoma'. The Maxillofacial Surgery Unit and the Dentistry Unit of the same hospital took care of his dental situation to avoid the spread of infective foci to the entire body. After 1 year and 3 months from the first cycle of chemotherapy, a bulky splenic mass was discovered. Laparoscopic biopsy revealed a relapse of the anaplastic lymphoma kinase-positive anaplastic large cell lymphoma in a splenic node. The patient is now alive in good conditions, and continuously followed-up by the Pediatric and Hemato-oncology Operative Unit of University Hospital of Parma. Rapidity of action and a correct multidisciplinary (oncology-maxillofacial surgery-dentistry) approach is the key to cure illness, promptly diagnose relapse and avoid the spread of infective foci from the patient's teeth during chemotherapy cycles. PMID:23296283

Guida, A; Meleti, M; Vescovi, P; Serpico, R; Lucchese, A; Lo Muzio, L; Bufo, P; Pannone, G

2012-12-07

168

Arteriovenous fistula and pseudoaneurysm of the anterior spinal artery caused by an epidural needle in a 5-year-old patient.  

PubMed

Authors present the case of a 5-year-old patient with a spinal arteriovenous fistula (AVF) and pseudoaneurysm of the anterior spinal artery (ASA) caused by a traumatic epidural needle stick injury. A discussion and relevant review of the literature follow. The boy had a remote history of a liver transplant and required neuraxial blockade for an unrelated abdominal surgical procedure. Initial insertion of the epidural needle at the T9-10 interspace yielded blood. A second attempt at T10-11 was successful. Delayed left leg weakness developed on postoperative Day 8, with an MR image showing a track injury through the cord and a ventral subarachnoid hematoma. Laminectomies from T-9 to T-11were performed emergently to decompress the spinal cord. The dura mater was opened, the ventral hematoma was evacuated, and brisk venous bleeding was controlled with cauterization. Postoperative spinal angiography demonstrated an AVF and pseudoaneurysm of the ASA. Repeat angiography at postoperative Week 4 demonstrated complete resolution of the AVF and pseudoaneurysm, probably due to intraoperative cauterization of the draining vein. The patient underwent a short course of rehabilitation and had no clinical or electrophysiological evidence of spinal cord damage at the 20-month follow-up. One should be cognizant of the possibility of a cord injury in a patient with new-onset neurological deficits following an interventional spine procedure. Neuroimaging is essential for prompt diagnosis and treatment. PMID:23311385

Alnaami, Ibrahim; Lam, Fred C; Steel, Graham; Dicken, Bryan; O'Kelly, Cian J; Aronyk, Keith; Mehta, Vivek

2013-01-11

169

Successful treatment of a 14-year-old patient with intestinal malrotation with laparoscopic Ladd procedure: case report and literature review.  

PubMed

Midgut malrotation is an anomaly of intestinal rotation that occurs during fetal development and usually presents in the neonatal period. We present a rare case of malrotation in a 14-year-old patient who presented with cramping, generalized right abdominal pain, and vomiting for a duration of one day. A computed tomography abdominal scan and upper gastrointestinal contrast studies showed malrotation of the small bowel without volvulus. Laparoscopy revealed typical Ladd's bands and a distended flabby third and fourth duodenal portion extrinsically obstructing the misplaced duodeno-jejunal junction. The Ladd procedure, including widening of the mesenteric base and appendectomy, was performed. Symptoms completely resolved in a half-year follow up period. Patients with midgut malrotation may present with vague abdominal pain, intestinal obstruction, or intestinal ischemia. The laparoscopic Ladd procedure is feasible and safe, and it appears to be as effective as the standard open Ladd procedure in the diagnosis and treatment of teenage or adult patients with intestinal malrotation. PMID:23684081

Nakajima, Yuka; Sakata, Hiroyuki; Yamaguchi, Tomohiro; Yoshie, Norichika; Yamada, Taihei; Osako, Takaaki; Terashima, Mariko; Mambo, Naomi; Saka, Ryuta; Nose, Satoko; Sasaki, Takashi; Okuyama, Hiroomi; Nakao, Atsunori; Kotani, Joji

2013-05-17

170

Combination of acupuncture and spinal manipulative therapy: management of a 32-year-old patient with chronic tension-type headache and migraine  

PubMed Central

Objective The purpose of this case study is to describe the treatment using acupuncture and spinal manipulation for a patient with a chronic tension-type headache and episodic migraines. Clinical Features A 32-year-old woman presented with headaches of 5 months' duration. She had a history of episodic migraine that began in her teens and had been controlled with medication. She had stopped taking the prescription medications because of gastrointestinal symptoms. A neurologist diagnosed her with mixed headaches, some migrainous and some tension type. Her headaches were chronic, were daily, and fit the International Classification of Headache Disorders criteria of a chronic tension-type headache superimposed with migraine. Intervention and Outcome After 5 treatments over a 2-week period (the first using acupuncture only, the next 3 using acupuncture and chiropractic spinal manipulative therapy), her headaches resolved. The patient had no recurrences of headaches in her 1-year follow-up. Conclusion The combination of acupuncture with chiropractic spinal manipulative therapy was a reasonable alternative in treating this patient's chronic tension-type headaches superimposed with migraine.

Ohlsen, Bahia A.

2012-01-01

171

Long-Term Results of Total Hip Arthroplasty with an Extensively Porous Coated Stem in Patients Younger than 45 Years Old  

PubMed Central

Purpose This study analyzed the long-term results of cementless total hip arthroplasty using an extensively porous coated stem in patients younger than 45 years old. Materials and Methods The clinical and radiographic results of 45 hips from 38 patients who underwent cementless total hip replacement arthroplasty with an AML prosthesis were reviewed retrospectively. The average follow-up was 12 years (range, 10-15 years). Results The average Harris hip score at the time of final follow-up was 87.3 (range 77-94) points. Forty two hips (93.3%) showed excellent and good clinical results. Osteolysis occurred around the stem in 20 hips (44.4%) and around the cup in 26 hips (57.8%). Stress-mediated femoral resorption was observed in 33 hips (73.3%) at 10 years. There was no incidence of resorption progressing after 5 years postoperatively. There was no stem loosening. Five hips were revised for osteolysis, cup loosening and polyethylene wear. Conclusion The long term results of total hip arthroplasty using an extensively porous coated stem were acceptable, and there was no case involving the progression of proximal bone resorption.

Moon, Kyong Ho; Park, Seung Rim; Choi, Seong Wook

2010-01-01

172

Social Development:: 2 Year Olds  

MedlinePLUS

... help you appreciate the importance of being a good role model, by demonstrating that children often do as we do, not as we say. The best way for your two-year-old to learn how to behave around other people is to be ...

173

A 44-year-old patient with a new-onset seizure disorder after vaccination against Japanese encephalitis: a case report  

PubMed Central

Introduction Seizure disorders can have a wide variety of causes. In many cases, however, the underlying cause remains unknown. Vaccinations, for example, can trigger seizures, especially during childhood. In the literature, many cases have been reported in which febrile convulsions occurred after the administration of different types of vaccines, such as the measles, mumps and rubella vaccine or the tetanus and diphtheria vaccine. Only a few cases of epilepsy after vaccination have thus far been described in adults. Case presentation In the case reported here, a 44-year-old German Caucasian man working as a soldier had a seizure the day after he received a third dose of Japanese encephalitis vaccine. Before this vaccination, he had received multiple vaccines that he had tolerated well. He underwent several drug therapies at various institutions but has continued to experience different forms of seizures for more than 18 months. The intervals between seizures were approximately six weeks in length. The present work discusses our patient’s history, including all diagnostic procedures and results, as well as treatment approaches. None of the examinations revealed a possible cause for the seizures. Since no structural or genetic causes were detected, the seizures were deemed most likely to have been caused by the vaccinations, especially vaccination against Japanese encephalitis. To date, no medication has prevented our patient from having repeated attacks. Conclusions To the best of our knowledge there have been no previous cases reported in the literature where seizures occurred after multiple vaccinations in general or after vaccinations against Japanese encephalitis in particular. Although vaccines are tested before release, the appearance of new adverse reactions cannot be prevented in all cases. Seizure after vaccination is difficult to treat. In our patient’s case, different approaches have not led to a satisfying result to date.

2013-01-01

174

Radiation-induced Malignant Fibrous Histiocytoma of the Maxillary sinus in a 25-year-old patient with Nasopharyngeal Carcinoma: Early MR Imaging Characteristics  

Microsoft Academic Search

The early MR imaging characteristics of a malig - nant fibrous histiocytoma (MFH) in a 25-year-old man under the radiation treatment of nasopharyn - geal carcinoma were presented in this study. The tumor developed four years and 9 months following the 3-dimentional conformal radiotherapy of naso - pharyngeal carcinoma. Early magnetic resonance imaging features were nonspecific for neoplasm and not

Cheng-Yu Chen; Yi-Jen Peng

2006-01-01

175

6-year-old girl with hydrocephalus.  

PubMed

With rare exceptions, pediatric tectal gliomas have been generally reported as low-grade tumors with relatively good prognosis. The patients are usually treated conservatively to manage the signs and symptoms of obstructive hydrocephalus. We report a case of a tectal glioma in a 6-years-old girl with histological features of anaplastic mixed oligoastrocytoma that continues to progress despite chemotherapy and radiation therapy. PMID:19744043

Chang, Howard T; Cuison, Reuben V; Gera, Renuka; Saah, Elna; Scott-Emuakpor, Ajovi; Abood, Christopher

2009-10-01

176

Evaluation the treatment outcomes of intracapsular femoral neck fractures with closed or open reduction and internal fixation by screw in 18-50-year-old patients in Isfahan from Nov 2010 to Nov 2011  

PubMed Central

Background: There is conflict of interest in the treatment of intracapsular femoral neck fractures and the outcomes. The aim of this study was evaluation the treatment outcomes of closed and open reduction and internal fixation with screw in 18–50-year-old patients. Materials and Methods: This clinical randomized study was conducted in Ayatollah Kashani Center in Isfahan from Nov 2010 to Nov 2011. In 42 patients selected in a randomized manner, fractures were reduced by closed reduction or open if necessary and C-ARM was controlled in AP and lateral plans. Movement range and femur pain severity were evaluated according to Visual analogue Scale (VAS) score at 3 and 6 months after surgery. Data were analyzed by SPSS 18. Chi-square, t-test, one-way analysis of variance (ANOVA), and descriptive statistics such as frequency distribution, mean, and mean deviation were used. Results: Forty-two patients with femoral neck fracture were treated by open [31 patients (73.8%)] or closed reduction [11 patients (26.2%)] and also osteosynthesis. Their mean age was 47.3 ± 9.8 years; 29 of them were males and 13 were females. Twelve patients had bad range of motion (ROM) (28.6%), 16 had intermediate ROM (38%), and 14 had good ROM (33.4%). After 6 months, 12 patients (28.6%) had bad ROM, 10 (23.8%) had intermediate ROM, and 20 (47.6%) had good ROM. There were 11 cases of non-union (35.5%) in the open reduction group and 4 in the closed group. Conclusion: This study showed that femoral neck fracture is associated with several complications, especially if open reduction was necessary. So, the surgical method and necessary equipments such as radiolucent bed, C-ARM machine, and implant cannulated screw set should be considered.

Javdan, Mohammad; Bahadori, Mehran; Hosseini, Alireza

2013-01-01

177

Cerebral amyloid angiopathy with co-localization of prion protein and beta-amyloid in an 85-year-old patient with sporadic Creutzfeldt–Jakob disease  

Microsoft Academic Search

We report on an 85-year-old woman with hypertensive cerebral arteriolosclerosis who presented with rapidly progressive encephalopathy\\u000a leading to death within 4 months. Magnetic resonance imaging showed mild cortical atrophy consistent with her age and diffuse\\u000a leukoaraiosis. Her CSF 14–3–3 protein was positive. Neuropathology showed severe spongiform change and gliosis in the grey\\u000a matter and immunohistochemistry revealed diffuse prion protein deposition in

Claire Paquet; Nicolas Privat; Rachid Kaci; Marc Polivka; Olivier Dupont; Stéphane Haïk; Jean Louis Laplanche; Jean Jacques Hauw; Françoise Gray

2008-01-01

178

Isolated aglossia in a six year old child presenting with impaired speech: a case report  

Microsoft Academic Search

INTRODUCTION: The most mobile organ of the body, the tongue is associated with various congenital anomalies; most of which are in association with many other systemic abnormalities. Rarely do they occur in isolation. Isolated aglossia, that we presented, is one of the more rare presentations. CASE PRESENTATION: Our patient is a 6-year-old male child of Asiatic origin from Kashmir (India),

Altaf Rasool; Mohammad Inam Zaroo; Adil Hafeez Wani; Mohammad Ashraf Darzi; Shiekh Adil Bashir; Akram Hussain Bijli; Shafaq Rashid

2009-01-01

179

3-D printout of a DICOM file to aid surgical planning in a 6 year old patient with a large scapular osteochondroma complicating congenital diaphyseal aclasia  

PubMed Central

A 6 year old girl presented with a large osteochondroma arising from the scapula. Radiographs, CT and MRI were performed to assess the lesion and to determine whether the lesion could be safely resected. A model of the scapula was created by post-processing the DICOM file and using a 3-D printer. The CT images were segmented and the images were then manually edited using a graphics tablet, and then an STL-file was generated and a 3-D plaster model printed. The model allowed better anatomical understanding of the lesion and helped plan surgical management.

Tam, Matthew D; Laycock, Stephen D; Bell, Duncan; Chojnowski, Adrian

2012-01-01

180

3-D printout of a DICOM file to aid surgical planning in a 6 year old patient with a large scapular osteochondroma complicating congenital diaphyseal aclasia.  

PubMed

A 6 year old girl presented with a large osteochondroma arising from the scapula. Radiographs, CT and MRI were performed to assess the lesion and to determine whether the lesion could be safely resected. A model of the scapula was created by post-processing the DICOM file and using a 3-D printer. The CT images were segmented and the images were then manually edited using a graphics tablet, and then an STL-file was generated and a 3-D plaster model printed. The model allowed better anatomical understanding of the lesion and helped plan surgical management. PMID:22690278

Tam, Matthew D; Laycock, Stephen D; Bell, Duncan; Chojnowski, Adrian

2012-01-01

181

A 37-year-old spinal cord-injured female patient, transplanted of multipotent stem cells from human UC blood, with improved sensory perception and mobility, both functionally and morphologically: a case study  

Microsoft Academic Search

HLA-matched UC blood-derived multipotent stem cells were directly transplanted into the injured spinal cord site of a 37-year-old female patient suffering from spinal cord injury (SPI). In this case, human cord blood (UCB)-derived multipotent stem cells improved sensory perception and movement in the SPI patient's hips and thighs within 41 days of cell transplantation. CT and MRI results also showed

K-S Kang; SW Kim; YH Oh; JW Yu; K-Y Kim; C-H Song; H Han

2005-01-01

182

Recurrent hemoptysis in a 62-year-old smoker  

PubMed Central

Tracheal papillary adenoma is a rare benign tumor. We report a case of papillary adenoma in a 62-year-old male smoker who presented with recurrent hemoptysis. The tumor was located in the upper third of trachea and forceps biopsy through flexible bronchoscopy was uncomplicated and diagnostic.

Gowrinath, Karanam; Ramakrishna, Baddukonda Appala; Shanthi, Vissa; Sujatha, Gogineni

2013-01-01

183

Laparoscopic Adjustable Gastric Banding in a Morbidly Obese 18-year-old with Hypertrophic Cardiomyopathy  

Microsoft Academic Search

In this case report, we present an 18-year-old morbidly obese male with complicating hypertensive cardiomyopathy who underwent\\u000a laparoscopic adjustable gastric band surgery. The patient had multiple comorbidities associated with his obesity, including\\u000a obstructive sleep apnea, systemic hypertension, asthma, and depression. Given the severity of his underlying cardiac pathology\\u000a and multiple previously unsuccessful attempts at weight loss with conventional medical and

Jasmine Waipa; Sanjeev Dutta; Craig T. Albanese; John M. Morton

2008-01-01

184

Fatal Case of Brucellosis Misdiagnosed in Early Stages of Brucella suis Infection in a 46-Year-Old Patient with Marfan Syndrome  

PubMed Central

We report a fatal case of Brucella suis endocarditis initially misdiagnosed by automated identification systems as Ochrobactrum anthropi infection in a patient with a history of Marfan syndrome and recreational feral swine hunting. This report emphasizes the need to consider brucellosis as a part of the differential diagnosis of acute febrile illness, particularly in patients with known risk of exposure.

Carrington, M.; Choe, U.; Ubillos, S.; Stanek, D.; Campbell, M.; Wansbrough, L.; Lee, P.; Churchwell, G.; Rosas, K.; Zaki, S. R.; Drew, C.; Paddock, C. D.; DeLeon-Carnes, M.; Guerra, M.; Hoffmaster, A. R.; Tiller, R. V.

2012-01-01

185

Seizure with single-pulse transcranial magnetic stimulation in a 35-year-old otherwise-healthy patient with bipolar disorder.  

PubMed

This case report describes a patient who developed a seizure with single-pulse transcranial magnetic stimulation during motor threshold estimation. The patient had no history of seizures in the past and no gross neurologic deficits. The only possible seizure-provoking factors were modest doses of lithium and chlorpromazine, which the patient was on, and family history of seizure in a brother. This report aims to highlight the fact that single-pulse transcranial magnetic stimulation may provoke a seizure even in the absence of gross neurologic abnormality. PMID:16127313

Tharayil, Biju Sunny; Gangadhar, B N; Thirthalli, Jagadisha; Anand, L

2005-09-01

186

Three-Column Osteotomies in the Treatment of Spinal Deformity in Adult Patients 60 Years Old and Older: Outcome and Complications.  

PubMed

ABSTRACT: Study Design. Retrospective review.Objective. To report and analyze the perioperative complications, radiographic results, and functional outcomes in elderly patients undergoing pedicle subtraction osteotomy (PSO) and/or vertebral column resection (VCR) procedures for spinal deformity correction.Summary of Background Data. To our knowledge, no studies have focused on 3-column osteotomies in the elderly.Methods. We retrospectively reviewed prospectively collected data for 51 consecutive patients ?60 years undergoing 3-three column osteotomies for spinal deformity correction (PSO, 36 patients; VCR, 13 patients; PSO and VCR, 2 patients) and who had at least 2 years' follow-up. We analyzed the perioperative complications; the preoperative, postoperative, and final follow-up radiographic measurements; and the preoperative, postoperative, and final follow-up functional outcome scores (using SRS-22 and Oswestry Disability Index). Hotelling's t-square test and the ? test were used for analysis (statistical significance, P < 0.05).Results. There were 9 (18%) major complications (5 with PSO and 4 with VCR) and 20 (39%) minor complications (14 with PSO and 6 with VCR). Compared with preoperative values, improvement at 6 weeks after surgery averaged 16° (range = 0°-42°) in thoracic scoliosis, 14° (range = 2°-25°) in lumbar scoliosis, 9° (range = 5°-35°) in thoracic kyphosis, -24° (range = -12° to 68°) in lumbar lordosis, 2.4 cm (range = 0-12 cm) in coronal balance, and 6.9 cm (range = -2 to 20 cm) in sagittal balance. At final follow-up, improvements in the coronal and sagittal balance were maintained. By final follow-up, compared to preoperative state, there were significant improvements in all 5 SRS-22 domains and in the Oswestry Disability Index.Conclusion. In the elderly patient, PSO and VCR can achieve significant restoration of sagittal and coronal balance and significant improvement in quality of life. However, both techniques can lead to serious complications and should be selectively used. PMID:23138408

Hassanzadeh, Hamid; Jain, Amit; El Dafrawy, Mostafa H; Ain, Michael C; Mesfin, Addisu; Skolasky, Richard L; Kebaish, Khaled M

2012-11-01

187

Probable dementia associated with Lewy body pathology as a cause of prolonged acute confusional state in a 79-year-old patient.  

PubMed

Differentiation of "dementia with Lewy body pathology" (DLB) and delirium may be problematic in some cases, due to some of their common clinical characteristics such as fluctuations and hallucinations. Longer duration of cognitive changes usually aids in DLB diagnosis. However, presentation of DLB with an abrupt onset as a prolonged confusional state and hallucinations is also, even if rarely, described. We report the case of an elderly patient with probable dementia with Lewy body pathology, presenting with a prolonged acute confusional state, in order to draw attention to its diagnostic difficulty and the importance of careful target-oriented anamnesis in such cases. This type of dementia should be included in the differential diagnosis of elderly patients presenting with otherwise unexplained prolonged acute confusional states. PMID:22842839

Bahat, Gulistan; Tufan, Fatih; Akin, Sibel; Erten, Nigun; Karan, Mehmet Akif

2012-04-01

188

Primary Sjögren syndrome in a 2-year-old patient: role of the dentist in diagnosis and dental management with a 6-year follow-up.  

PubMed

BACKGROUND. Primary Sjögren syndrome is a rare autoimmune disease, especially in children, mainly affecting girls (77%), and usually diagnosed around 10 years of age. Diagnosis during childhood is difficult, especially because of the diversity of the clinical presentation and difficulty obtaining reliable history data, accounting for a higher frequency of underdiagnosed cases. Differential conditions should be considered, especially the ones that promote xerostomia, such as diabetes, ectodermal dysplasia, rheumatoid arthritis, scleroderma, systemic lupus erythematosus, sarcoidosis, lymphoma, HIV and HTLV infection. Conditions associated with parotid enlargement should also be excluded, including juvenile recurrent parotitis (JRP), sialadenosis, sarcoidosis, lymphoma, infectious parotitis caused by streptococcal and staphylococcal infections, viral infections (paramyxovirus, Epstein-Barr virus, cytomegalovirus, and parvovirus), and diffuse infiltrative lymphocytosis syndrome (associated with HIV infection), and rare congenital conditions, such as polycystic parotid disease. CASE REPORT. A paediatric female patient was referred to our clinic for dental treatment complaining about dry mouth, oral discomfort, and dysphagia. The patient presented five of the required criteria to establish the diagnosis of pSS, including ocular symptoms, oral symptoms, evidence of keratoconjunctivitis sicca, focal sialadenitis confirmed by minor salivary gland biopsy, and evidence of major salivary gland involvement. Our patient did not have positive SS-A and SS-B autoantibodies. According to the literature, about 29% of individuals with pSS can present seronegativity for SS-A (anti-Ro) antibodies and about 33% can present seronegativity for SS-B (anti-La) antibodies. CONCLUSION. To the best of our knowledge, this is the youngest patient reported in the scientific English literature with pSS. Primary Sjögren syndrome has a wide clinical and immunologic spectrum and may progress with increased morbidity. Clinicians must be aware of the development of pSS in such an early age and exclude all possible differential findings to provide early diagnosis and treatment. PMID:21623979

De Oliveira, Marcio Augusto; De Rezende, Nathalie Pepe Medeiros; Maia, Célia Márcia Fernandes; Gallottini, Marina

2011-05-31

189

Phase II trial of arsenic trioxide in relapsed and refractory acute myeloid leukemia, secondary leukemia and\\/or newly diagnosed patients at least 65 years old  

Microsoft Academic Search

The prognosis for patients with relapsed\\/refractory AML, secondary leukemia and AML in older adults is extremely poor. An appealing alternative approach to intensive cytotoxic chemotherapy is to induce apoptosis with a novel agent. There is in vitro evidence that arsenic trioxide (ATO) has anti-proliferative and pro-apoptotic effects on myeloid leukemia cell lines. To evaluate efficacy and toxicities of ATO, we

Simrit Parmar; Lynn M Rundhaugen; Larry Boehlke; MaryBeth Riley; Chadi Nabhan; Adekunle Raji; John L Frater; Martin S Tallman

2004-01-01

190

Higher fungal infection rate in elderly patients (more than 80 years old) suffering from diffuse large B cell lymphoma and treated with rituximab plus CHOP  

Microsoft Academic Search

Although adding rituximab to standard cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy is an\\u000a efficacious and well-tolerated regimen in elderly patients with diffuse large B cell lymphoma (DLBCL), it may increase susceptibility\\u000a to opportunistic infections, and such cases have been reported. Our study was to identify the risk factors for fungal infection\\u000a in a retrospective case-control matched study of 34

Peng-Chan Lin; Liang-Tsai Hsiao; Say-Bee Poh; Wei-Shu Wang; Chueh-Chuan Yen; Ta-Chung Chao; Jin-Hwang Liu; Tzeon-Jye Chiou; Po-Min Chen

2007-01-01

191

Comparison of Acceptance, Preference, and Efficacy Between Jet Injection INJEX and Local Infiltration Anesthesia in 6 to 11 Year Old Dental Patients  

PubMed Central

Abstract Needleless devices have been developed to provide anesthesia without injections. Little controlled research has examined the acceptability of needleless devices in pediatric patients. The aims of the study were to compare children’s acceptance and preference for one type of needleless jet injection with classical local infiltration as well as to evaluate the efficacy of the needleless anesthesia. Eighty-seven nonfearful children with no previous experience of dental anesthesia were studied using a split-mouth design. The first dental procedure was performed with the classical infiltration anesthesia. The same amount of anesthetic was administered using the INJEX needleless device in a second session 1 week later, during which a second dental procedure was performed. Patients rated their acceptance and preference for the 2 methods, and the dentist recorded data about the need for additional anesthesia. More negative experiences were reported for the INJEX method. Most (73.6%) of the children preferred the traditional method. Among the 87 treatment procedures attempted following the use of INJEX, 80.5% required additional anesthesia, compared with 2.3% of those attempted following traditional infiltration. Traditional infiltration was more effective, acceptable, and preferred, compared with the needleless INJEX.

Arapostathis, Konstantinos Nikolaos; Dabarakis, Nikolaos Nestoras; Coolidge, Trilby; Tsirlis, Anastasios; Kotsanos, Nikolaos

2010-01-01

192

A prospective study of reduced-dose three-course CHOP followed by involved-field radiotherapy for patients 70 years old or more with localized aggressive non-Hodgkin's lymphoma  

SciTech Connect

Purpose: We conducted a multicenter prospective study to evaluate the efficacy and safety of reduced-dose three-course CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone) followed by involved-field radiotherapy for elderly patients with localized aggressive non-Hodgkin's lymphoma. The primary endpoint was compliance with the combined modality. Methods and Materials: This study included untreated patients, {>=}70 years old, with diffuse aggressive lymphoma, Stage IA or contiguous nonbulky Stage IIA. 80%-CHOP (cyclophosphamide 600 mg/m{sup 2}, doxorubicin 40 mg/m{sup 2}, vincristine 1.1 mg/m{sup 2}, and prednisolone at 80 mg/day for 5 days) was repeated every 3 weeks. After three cycles of chemotherapy, involved-field radiotherapy was performed with a radiation dose of 30-50 Gy in 15-28 fractions. Results: Twenty-four patients with a median age of 75 years (range, 70-84 years) were enrolled. The compliance rate of the protocol study was 87.5% (95% confidence interval [CI], 67.6-97.3). Three patients received only two cycles of chemotherapy because of toxicity or second neoplasm. There were no deaths caused by severe toxicity. The 3-year progression-free and overall survival rates were 83.1% (95% CI, 75.4-90.8) and 82.9% (95% CI, 75.1-90.6), respectively. Conclusion: Three-course 80%-CHOP followed by involved-field radiotherapy may be safe for administration to elderly patients over 70 years old. The next step is to evaluate three-course 80%-CHOP and rituximab followed by radiotherapy in elderly patients with localized disease.

Shikama, Naoto [Department of Radiology, Shinshu University School of Medicine, Matsumoto (Japan)]. E-mail: shikama@hsp.md.shinshu-u.ac.jp; Oguchi, Masahiko [Department of Radiation Oncology, Cancer Institute Hospital, Tokyo (Japan); Isobe, Koichi [Department of Radiology, Chiba University Hospital, Chiba (Japan); Nakamura, Katsumasa [Department of Radiology, Kyushu University Graduate School of Medicine, Fukuoka (Japan); Tamaki, Yoshio [Department of Radiology, Gunma Prefectural Cancer Center, Gunma (Japan); Hasegawa, Masatoshi [Department of Radiation Oncology, Nara Medical University, Nara (Japan); Kodaira, Takeshi [Department of Radiation Oncology, Aichi Cancer Center, Nagoya (Japan); Sasaki, Shigeru [Department of Radiology, Shinshu University School of Medicine, Matsumoto (Japan); Kagami, Yoshikazu [Department of Radiation Oncology, National Cancer Center, Tokyo (Japan)

2006-09-01

193

Axillary Metastasis as the First Manifestation of Occult Breast Cancer in a Male Patient  

Microsoft Academic Search

SummaryBackground: The aim of this study was to investigate the clinicopathologic features of male breast cancer. Case Report: We present the clinicopathologic data of a 72year-old male patient with occult breast cancer, who was diagnosed and underwent surgery in our hospital. The diagnosis was confirmed by histological examination, and the patient underwent modified radical mastectomy and axillary dissection. The histological

Guo-Li Gu; Shi-Lin Wang; Xue-Ming Wei; Li Ren; Fu-Xian Zou

2009-01-01

194

TFE3 Translocation-Associated Renal Cell Carcinoma Presenting as Avascular Necrosis of the Femur in a 19-Year-Old Patient: Case Report and Review of the Literature  

PubMed Central

In the United States, renal cell carcinoma (RCC) accounts for approximately 3% of adult malignancies and 90–95% of all neoplasms arising from the kidney. According to the National Cancer Institute, 58?240 new cases and 13?040 deaths from renal cancer will occur in 2010. RCC usually occurs in older adults between the ages of 50 and 70 and is rare in young adults and children. We describe a case of a TFE3 translocation-associated RCC in a 19-year-old patient presenting as avascular necrosis of the femur. Due to the rarity of this malignancy, we present this case including a review of the existing literature relative to diagnosis and treatment.

Nelius, T.; Al-Khalil, I.; Vordermark, J.; Rinard-Holden, K.; Cammack, T.; Mamlok, V.; Filleur, S.

2011-01-01

195

Tracheal mucoepidermoid carcinoma in a 7-year-old child  

Microsoft Academic Search

Mucoepidermoid cancers are rare tumors that arise from the serous and mucous glands of the upper airway and salivary glands. Patients, especially children, with tumors that arise in the trachea and upper airways are often misdiagnosed as asthmatic and are treated with bronchodilators without resolution. A 7-year-old girl who had been diagnosed as asthmatic was subsequently found to have a

Seiichi Noda; Sudhir Sundaresan; Eric N Mendeloff

1998-01-01

196

Cyanotic tetralogy of Fallot in a 77 year old man  

Microsoft Academic Search

We report the clinical details of a 77 year old man with classical tetralogy of Fallot. The patient had clubbing and cyanosis at birth, and exertional squatting in childhood. He was asymptomatic as an adult until the seventh decade, when he developed biventricular failure and had an episode of bacterial endocarditis. He finally died of cerebral infarction and bronchopneumonia following

S. H. Thomas; P. Bass; H. Pambakian; J. H. Marigold

1987-01-01

197

Giant mesenteric lipoblastoma in a 4-year-old child.  

PubMed

Lipoblastoma is a rare benign neoplasm of embryonal fat that occurs typically in infancy and childhood. An unusual case of a giant mesenteric lipoblastoma in a 4-year-old child is presented. The lipoblastoma was completely removed. Histopathologic examination confirmed the diagnosis of mesenteric lipoblastoma. Observation of the patient for 4 months postoperatively showed no evidence of recurrence. PMID:19361656

Tang, Xiao Bing; Zhang, Tao; Bai, Yu Zuo; Wang, Wei Lin

2009-04-01

198

The Hybrid III 10-Year-Old Dummy.  

PubMed

This paper describes the design and development of the Hybrid III 10-year-old crash test dummy. The size of the dummy was chosen to fill the gap between the Hybrid III 6-year-old and the Hybrid III small adult female dummy which is also about the size of a 13-year-old teenager. Characteristic dimensions and segment weights of the dummy are based on the anthropometry of the average 10-year-old. Biofidelity response guidelines for forehead, sternum and knee impacts and for fore/aft neck bending are scaled from the midsize adult male biofidelity guidelines taking into account the effects of differences in size, mass and material properties due to the age difference. The dummy is similar in construction to the other Hybrid III dummies except it has an adjustable lumbar spine which allows the dummy to slouch and its neck structure is aligned with its thoracic spine. Data are given showing the responses of the prototype dummy relative to its biofidelity guidelines. The prototype dummy was evaluated in out-of-position air bag tests and three-point belt tests to evaluate its durability and ease of use. The prototype dummy has demonstrated acceptable biofidelity, repeatability and durability and the design has been approved by the SAE Hybrid III Dummy Family Task Group for production. PMID:17458751

Mertz, H J; Jarrett, K; Moss, S; Salloum, M; Zhao, Y

2001-11-01

199

HFOV Case Study 14 year old  

Microsoft Academic Search

A 14-year-old female is admitted with a decreased level of consciousness and abdominal bleeding. She also complains of abdominal pain, diaphoresis, and cramping in the left upper quadrant and periumbilical area. A diagnostic laparoscopy is performed, noting copious bleeding from a hemorrhagic cyst. She experiences hypotension and a decreased hemoglobin and hematocrit. Packed red blood cells are transfused. After fluid

Student Copy

200

Phase I/II study of vinorelbine and exisulind as first-line treatment of advanced non-small cell lung cancer in patients at least 70 years old: a Wisconsin Oncology Network Study  

PubMed Central

INTRODUCTION Exisulind is an apoptotic agent with preclinical activity in non-small cell lung cancer (NSCLC). Vinorelbine is safe and effective in older patients with advanced NSCLC. We assessed these agents together as palliative treatment for older patients with advanced NSCLC. METHODS Chemotherapy-naïve patients ? 70 years old with stage IIIB-IV NSCLC and a performance status (PS) ? 2 were eligible. Primary endpoints were the maximum tolerated dose (MTD, phase I) and time-to-progression (TTP, phase II) of oral exisulind with 25 mg/m2/week of intravenous (IV) vinorelbine on a 28-day cycle. Patients with clinical benefit after six cycles of this combination received exisulind alone. RESULTS Fourteen phase I patients (median PS 1; median age 78 years) were enrolled. Dose-limiting toxicities included grade 3 constipation (one patient), grade 3 febrile neutropenia (one patient) and grade 3 diarrhea (one patient). The MTD of oral exisulind with 25 mg/m2/week of IV vinorelbine was 125 mg twice daily. Thirty phase II patients (median PS 1; median age 78 years) were enrolled. Grade ? 3 neutropenia occurred in 14/30 patients. Two patients experienced neutropenic fever. There were no complete responses, one partial response and 12 patients with stable disease as their best response. The objective response rate was 4.0% (95% CI: 0.1–20.4%). Phase II median TTP was 4.7 months (95% CI: 3.1 – 9.3 months) and median OS was 9.6 months (95% CI: 6.6 – 19.1 months). CONCLUSIONS This combination is safe, appears to have activity in the elderly with advanced NSCLC and a PS ? 2, and warrants further investigation.

Attia, Steven; Traynor, Anne M.; Kim, KyungMann; Merchant, Joseph J.; Hoang, Tien; Ahuja, Harish G.; Beatty, Peter A.; Hansen, Richard M.; Masters, Gregory A.; Oettel, Kurt R.; Shapiro, Gary R.; Larson, Martha M.; Larson, Marilyn L.; Schiller, Joan H.

2008-01-01

201

Pathology Case Study: A 42-Year-Old Man with Hip Pain  

NSDL National Science Digital Library

This is a genitourinary pathology case study presented by the University of Pittsburgh Department of Pathology in which a 42-year-old male has hip pain and an elevated PSA. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in genitourinary pathology.

Nine, Jeff S.; Hakam, Ardeshir

2007-08-14

202

Pathology Case Study: A 50-Year-Old Man with a Submandibular Mass  

NSDL National Science Digital Library

This is an ear, nose, & throat case study case study presented by the University of Pittsburgh Department of Pathology in which a 48- or 50-year-old male has an asymptomatic enlarging white submandibular mass. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in ear, nose, and throat medicine.

Schubert, Eric

2007-08-10

203

Eleven-year-old boys in trouble  

Microsoft Academic Search

A study of the Detroit police files of 334 eleven-year old boys and of 3,787 who had passed their twelfth birthday indicated that the former came in greater proportion from poorer socio-economic levels, and were more dependent on their parents for spending money. The younger group expressed less hostile feelings toward adults, perhaps thus showing only a more conventional pattern

William W. Wattenberg

1953-01-01

204

A novel case of t(X;1)(p11.2;p34) in a renal cell carcinoma with TFE3 rearrangement and favorable outcome in a 57-year-old patient.  

PubMed

Renal cell carcinoma (RCC) with translocation involving Xp11.2 (Xp11.2-RCC) is a rare neoplasm that usually occurs in children and young adults. This incidence is underestimated in adults because its morphological similarities with clear-cell RCC or papillary RCC2,3, as well as immunohistochemical and cytogenetic analyses are not carried out systematically in adults. We present a novel case of Xp11.2-RCC in a 57-year-old woman. The histologic features were those of a clear-cell RCC. Molecular cytogenetic analysis showed an uncommon t(X;1)(p11.2;p34) with TFE3 rearrangement and no alteration of chromosome 3. The immunohistochemical analysis showed expression of the TFE3 protein. Only nine cases of (X;1)(p11.2;p34) have been published, most of them occurring in children or young adults. To our knowledge, this is the second report of such a translocation in a patient older than 55 years. After a follow-up period of 13 months, the patient showed no evidence of disease. The clinical outcome was favorable, indicating that this particular translocation might be associated with a good prognosis. This observation confirms that Xp11.2-RCC are very likely to be underestimated in adults older than 40 years, and it highlights the importance of performing immunohistochemical and cytogenetic analyses in RCC for accurate diagnosis. PMID:20620589

Haudebourg, Juliette; Hoch, Benjamin; Fabas, Thibault; Burel-Vandenbos, Fanny; Carpentier, Xavier; Amiel, Jean; Cardot-Leccia, Nathalie; Michiels, Jean-François; Pedeutour, Florence

2010-07-15

205

MULTIPLE ERUPTIVE PILOMATRICOMAS IN A 9-YEAR-OLD BOY WITH GLIOBLASTOMA.  

PubMed

? A 9-year-old male presented to our dermatology clinic with a recent history of developing numerous cutaneous pilomatricomas, and was subsequently discovered to have sustained a recurrence of his glioblastoma multiforme. Immunohistochemical staining of a representative pilomatricoma and his original brain tumor revealed upregulation and nuclear localization of beta-catenin, a sign associated with poor prognosis in glioblastoma. We hypothesize that the development of multiple pilomatricomas may have been a hallmark of this patient's tumor recurrence and provide support for a recent report of an association between multiple pilomatricomas and gliomatosis cerebri. PMID:22304393

Hollmig, S Tyler; Tollefson, Megha M; Kim, Jinah; Khuu, Phuong

2012-02-01

206

A 3YearOld Girl with Headaches and Ataxia  

Microsoft Academic Search

Tadanori Tomita: This is a 3.5-year-old Caucasian female from the Island of Crete in Greece. She had been normal until 2 months prior to admission, when she started to have increasing headaches, instability and dizziness involving ataxia. She also started to have a head tilt. The patient was noted to have an ocular anomaly by a local ophthalmologist in Greece,

Harold Rekate; Tadanori Tomita; Guillermo A. de Leon; Mary Ann Radkowski

1999-01-01

207

Identification of Strategies for Penetrating the 19-to-23-Year-Old Recruiting Market.  

National Technical Information Service (NTIS)

Nine marketing strategies were evaluated for their potential effectiveness in attracting and enlisting a target population of 19-to 23-year old, unmarried, nonprior-service males with high school diplomas. The evaluation was based on information obtained ...

A. P. Romanczuk B. E. Goodstadt C. L. Colby K. Fernandes

1982-01-01

208

Oral mucosal lichen planus in nine-year-old child.  

PubMed

Lichen planus (LP) is a fairly distinctive mucocutaneous disease. The etiology of the condition appears to be complex and multifactorial, with unique histopathological features. Immunofluorescence studies have provided some insight into a proposed immunopathogenesis. LP is seen frequently in the middle-aged and elderly population. The female-to-male ratio is approximately 2:1. Children are rarely affected. The incidence of oral LP in children is reportedly high among Asians. We present a 9-year-old Indian child with the documented clinical aspects, histopathology and immunofluorescence studies. PMID:22338815

Anuradha, Ch; Reddy, G Sridhar; Nandan, S R K; Kumar, Shamala Ravi; Reddy, B Venkat Ramana

2011-11-01

209

A craniopharyngioma in a seven-year-old dog.  

PubMed

A seven-year-old male Border Collie was presented with a history of lethargy, episodic circling, incoordination and polydypsia. Physical examination revealed depression, obesity and bradycardia. A neurological examination indicated the possible presence of a space-occupying lesion in the brain. Results of the clinical investigation revealed hyposthenuria, sinus bradycardia and increased concentration of protein in the cerebrospinal fluid. A computerised axial tomography scan revealed a mass in the region of the hypophysis. The dog was euthanased and a post mortem examination confirmed the presence of a craniopharyngioma. PMID:1941890

Eckersley, G N; Geel, J K; Kriek, N P

1991-06-01

210

Primary retroperitoneal mucinous cystadenocarcinoma in a male patient: a case report  

Microsoft Academic Search

In the literature, 51 cases of primary retroperitoneal mucinous cystadenocarcinoma have been published. We report the fourth case occurring in a male patient. The 42-year-old patient presented with multiple retroperitoneal cystic masses causing abdominal discomfort without alteration of the global clinical state. The masses were totally removed by a two-stage surgery. No other treatment has been introduced. After a follow-up

Abdelmalek Hrora; Sanae Reggoug; Houda Jallal; Farid Sabbah; Abdessalam Benamer; Mouna Alaoui; Mohamed Raiss; Mohamed Ahallat

2009-01-01

211

Report of a male patient with brain metastases from breast cancer  

Microsoft Academic Search

As in female patients, the clinical course in male patients with breast cancer is determined mainly by tumor stage. The literature contains very limited data on either the occurrence or the treatment of CNS metastases.This paper presents the case report of a 69-year-old man with multiple brain metastases 7 years after a diagnosis of lymph-node positive breast cancer, which had

C Nieder; P. J Jost; A. L Grosu; C Peschel; M Molls

2003-01-01

212

Sialolithiasis in a 10 year old child.  

PubMed

Sialolithiasis is often observed in the oral region, and is caused by the development of a calculus in the salivary gland or duct. This disease is mostly seen in adults or young adults, and seldom develops in children. Of all the cases of sialolithiasis, only 3% are seen in the pediatric population. The clinical presentation typically consists of a painful swelling of the involved salivary gland at meal times, as the obstruction is most acute at this time. The clinical signs often lead to an easy diagnosis. The salivary gland most commonly affected is the submandibular gland. In this paper, we have reported the case of a 10 year old female with sialolithiasis of the left submandibular duct. The treatment consisted of the use of lemon and orange drop candies, which stimulated the salivary flow and in turn resulted in the expulsion of stone. PMID:23257494

Marwaha, Mohita; Nanda, Kanwar Deep Singh

213

A 32-year-old male with brainstem lesions.  

PubMed

Schwannosis is a condition characterized by a benign proliferation of Schwann cells and an incomplete myelination of central nervous system axons following different chronic stimuli. It. has been mainly observed in the spinal cord. Various hypotheses have been put forward with respect to the appearance of Schwann cells inside the central nervous system since they exclusively populate the peripheral nervous system. According to these hypotheses, schwannosis seems to be either the result of aberrant migration under certain conditions, especially in response to spinal cord injury, or as a developmental abnormality in form of ectopia during ontogenesis.We report, for the first time, on the multifocal occurrence of this rare nosological entity in the brain stem. Furthermore we compare the histological and immunohistochemical profile of schwannosis to that of an intracerebral schwannoma taken from our archive. PMID:23217006

Kanakis, Dimitrios N; Kamphausen, Thomas; Van de Nes, Johannes

2013-01-01

214

11 year-old girl undergoing scoliosis surgery.  

PubMed

We report the case of an 11-year-old girl operated on for a severe left thoracolumbar scoliosis. Pedicular screw insertion and rod positioning was technically successful, but five days later, for signs of an early infection, the wound revised and unexpectedly the patient died during surgery. Autopsy recognized a diffuse cerebral cortical venous air embolism as the cause of death and excluded pulmonary embolism and associated cardiac defects.This is the first and unique case describing a fatal paradoxical air venous cerebral embolism in a pediatric patient undergone spine surgery: the possible mechanism involving azygos and jugular veins systems is discussed. PMID:22697383

De-Giorgio, Fabio; Arena, Vincenzo; Turturro, Francesco; d'Aloja, Ernesto; Miscusi, Massimo

2012-07-01

215

The Intentions of Men 23 to 29 Years Old to Join the Military: Results of a National Survey.  

ERIC Educational Resources Information Center

|Since the population of 17-to-21-year-old males, the traditional source for military recruitment, will decline sharply during the 1980s, consideration is being given to recruiting males aged 23-29. A national survey was conducted to assess the interest of 23-to-29-year-old men in joining the military under present conditions and with monetary…

Borack, Jules I.

216

Protean manifestations of lipoid proteinosis in a 16-year-old boy.  

PubMed

We report a 16-year-old Japanese male with lipoid proteinosis showing various skin manifestations. The patient was born to nonconsanguineous parents and none of his relatives was similarly affected. The patient suffered from a hoarse voice and refractory temporal epilepsy from early childhood. Computed tomography scanning of the brain showed bilateral calcification in the temporal lobes, a characteristic feature of lipoid proteinosis. On physical examination, various skin manifestations, including papules and haemorrhagic blisters, acne-like scars at sites of minor trauma or friction, and beads of small papules along the free margins of the eyelids were noted. A skin biopsy showed deposits of homogeneous hyaline-like material, positive on periodic acid-Schiff staining, throughout the dermis, particularly around small blood vessels. It is noteworthy that a range of characteristic skin lesions can be present in a patient with lipoid proteinosis even with mild systemic involvement. PMID:10671967

Nagasaka, T; Tanaka, M; Ito, D; Tanaka, K; Shimizu, H

2000-01-01

217

Oral rehabilitation of a 12-year-old patient diagnosed with a central giant cell granuloma using a fibula graft and an implant-supported prosthesis: a clinical report.  

PubMed

This clinical report describes the oral rehabilitation of a 12-year-old boy with a central giant cell granuloma of the mandible. He underwent en bloc resection of a central giant cell granuloma, free vascularized fibula reconstruction, implant placement, and prosthesis fabrication. The multidisciplinary approach successfully restored function and esthetics. Considerations regarding the extensive surgical and prosthetic rehabilitation of a young adult with remaining growth are discussed. PMID:18395534

Lee, Heeje; Ercoli, Carlo; Fantuzzo, Joseph J; Girotto, John A; Coniglio, John U; Palermo, Matthew

2008-04-01

218

Terrible Twos: Why Are 2-Year-Olds So Difficult?  

MedlinePLUS

... be reprinted for personal, noncommercial use only. Terrible twos: Why are 2-year-olds so difficult? By Mayo Clinic staff ... your e-mail address Sign up Question Terrible twos: Why are 2-year-olds so difficult? I' ...

219

Recurrent diarrhea in a 26-year-old man.  

PubMed

This is a case report of a 26-year-old healthy man with chronic diarrhea for 2 years. He was initially believed to have irritable bowel syndrome by his primary care physician after all stool studies yielded negative results. His symptoms persisted, which prompted a referral to a gastroenterology specialist. The patient's esophagogastroduodenoscopy revealed variable villous blunting and a paucity of CD 138 plasma cells, which helped reveal the final diagnosis. This cases illustrates a unique presentation of a common primary immunodeficiency that allergy/immunology specialists, along with primary care specialists, will likely encounter. PMID:22221444

Baker, Troy W; Stokes, Shayne; Clawson, Jacob; Garrett, Todd; Sacha, Josh J; Gonzalez-Reyes, Erika

220

Alcoholic ketoacidosis in an 11-year-old boy.  

PubMed

A history of ethanol consumption combined with vomiting, anion gap metabolic acidosis, and altered mental status is consistent with a broad differential diagnosis, which requires a systematic approach. Alcoholic ketoacidosis is rare after binge drinking in the naïve individual and typically occurs in patients with heavy, chronic use. We present the case of an 11-year-old boy with acute ethanol intoxication and a clinical course that is most consistent with alcoholic ketoacidosis. Alcoholic ketoacidosis should be considered in the differential diagnosis of children with unexplained ketoacidosis when there is history or evidence of ethanol consumption combined with the appropriate clinical presentation. PMID:18347497

Manini, Alex F; Hoffman, Robert S; Nelson, Lewis S

2008-03-01

221

[Malignant insulinoma in an 84-year-old woman].  

PubMed

The malignant insulinoma is a very strange disorder (6% of the diagnosed insulinoma whose incidence is one to eight cases records in a million inhabitant per year) specially in people under 40 years or over 70 years old. We report the case of a woman, aged 84, who was admitted because of lost of consciouness and sweating. The patient suffers pancreatic tumour that products insuline with liver metastasis. She shows a good response when treated with diazoxide. We also revise her clinical, diagnostic and therapeutic features in this disease. PMID:12666308

Val, E; Saiz, F; Iriarte, A; Racionero, M

2003-01-01

222

Physical Fitness and Cognitive Function in an 85YearOld Community-Dwelling Population  

Microsoft Academic Search

Background: Little is known about the association between physical fitness and cognitive function in very elderly people (over 80 years of age). Objectives: To evaluate that relationship in 85-year-old community-dwelling individuals. Methods: Out of 207 participants (90 males, 117 females) who were 85 years old and community-dwelling, 205 completed the Mini-Mental State Examination (MMSE) for evaluating cognitive function. The numbers

Y. Takata; T. Ansai; I. Soh; Y. Kimura; Y. Yoshitake; K. Sonoki; S. Awano; S. Kagiyama; A. Yoshida; I. Nakamichi; T. Hamasaki; T. Torisu; K. Toyoshima; T. Takehara

2008-01-01

223

Metastatic pulmonary calcification in multiple myeloma in a 45-year-old man.  

PubMed

Metastatic calcification has been associated with multiple-myeloma-induced hypercalcemia. Despite of a relatively high prevalence of metastatic pulmonary calcification in patients with multiple myeloma, only a few cases have been clinically and radiologically detected. A 45-year-old Hispanic male presented to the Emergency Department with complaint of worsening weakness and myalgia. Laboratory findings revealed renal insufficiency and hypercalcemia. CT scan of chest revealed calcified pleural and pulmonary nodule. Technetium (Tc) 99 bone scan revealed diffuse activity in the pulmonary parenchyma consistent with metastatic pulmonary calcification. Metastatic pulmonary calcification, despite its high prevalence, remains undetected. This is, in part, due to its radiographic characteristic properties that evade detection by routine imaging studies. We present a case of a metastatic pulmonary calcification in a patient diagnosed with multiple myeloma and chronic kidney disease, as well as a brief literature review including clinical findings and treatment options. PMID:23662234

Surani, Salim R; Surani, Sara; Khimani, Amina; Varon, Joseph

2013-04-11

224

Lobular Breast Cancer in a Male Patient with a Previous History of Irradiation Due to Hodgkin's Disease  

PubMed Central

Background Male breast cancer is rare and represents less than 1% of all breast cancers. Considering the fact that the male breast most often does not consist of lobules and acini, lobular carcinoma of the male breast is exceptionally rare. Case Report In this paper we present a unique case of alveolar variant of lobular male breast cancer in a 56-year-old patient. Conclusion According to our knowledge this is the first presentation of an alveolar variant of lobular male breast cancer that appeared 14 years after chemo- and radiotherapy for the treatment of Hodgkin's disease.

Ninkovic, Srdjan; Azanjac, Goran; Knezevic, Milan; Radovanovic, Dragce; Canovic, Dragan; Nedovic, Jasmina; Mitrovic, Slobodanka

2012-01-01

225

Basilar impression and osteogenesis imperfecta in a three-year-old girl: CT and MRI  

Microsoft Academic Search

A 3-year-old girl with osteogenesis imperfecta developed symptomatic basilar impression. Her neurological symptoms were treated\\u000a by foramen magnum decompression and laminectomy. This is an unusually young patient to have this condition.

P. J. Rush; D. Berbrayer; B. J. Reilly

1989-01-01

226

[A 78 year-old man with hyponatremia, malaise and weight loss caused by a pituitary mass].  

PubMed

A 78 year-old male was admitted for rehabilitation after a trans-tibial amputation three months earlier. Scheduled training with a prosthetic leg was postponed due to muscle atrophy and weakness. As the patient's status deteriorated, blood results showed worsening hyponatremia.Work-up revealed pituitary insufficiency caused by a pituitary mass. The patient's general health improved greatly and the hyponatremia corrected after hormonal replacement therapy with hydrocortisone, thyroxin and testosterone was initiated. Key words: hyponatremia, malaise, weight loss, pituitary insufficiency, pituitary adenoma. PMID:22460436

Gudnason, Gudni Arnar; Valtysdottir, Sigridur Thordis; Valdimarsson, Trausti; Thorvaldsson, Stefan; Magnusson, Thorvaldur

2012-04-01

227

Subarachnoid hemorrhage in a 13-year-old girl.  

PubMed

At 5:20 pm, a local flight team was activated to respond for an interfacility transfer of a 13-year-old girl with a subarachnoid hemorrhage. In the history obtained, the patient's parents noted that she had not been feeling well for the past several days. She had been complaining of intermittent dizziness and a persistent headache. Until the onset of these prodromal events, she had been active with no medical history. That afternoon, the child was playing with her friends at the school playground. As the group was walking home, they noticed that the patient was not with them. They subsequently returned and found her lying face-down in the bushes, unresponsive, with agonal respirations. PMID:20826349

Tilney, Peter

228

Rapunzel Syndrome Case Report: A 13-year-old Girl.  

PubMed

Bezoars are masses, which are commonly encountered in patients after stomach surgery or in those with psychiatric problems, formed by the accumulation of intraluminal nondigestible substances that can lead to obstruction of the stomach and the small intestine. The anatomical changes in the gastrointestinal tract are known to cause bezoar formation. In the absence of an anatomical change, psychiatric disorders such as trichotillomania may lead to the formation of trichobezoars in the stomach. The so-called Rapunzel syndrome is the extension of the bezoars down to the duodenum and the jejunum, which is a rare condition. In this paper, a 13-year-old patient with trichotillomania is reported, who was admitted to our clinic with nausea, vomiting, and fatigue complaints, in whom a giant trichobezoar was identified, which completely filled the stomach and duodenum, without causing obstruction. PMID:23766614

Ozdemir, Hakan; Ozdemir, Zehra U; Sahiner, Ibrahim T; Senol, Metin

2012-10-01

229

Rapunzel Syndrome Case Report: A 13-year-old Girl  

PubMed Central

Bezoars are masses, which are commonly encountered in patients after stomach surgery or in those with psychiatric problems, formed by the accumulation of intraluminal nondigestible substances that can lead to obstruction of the stomach and the small intestine. The anatomical changes in the gastrointestinal tract are known to cause bezoar formation. In the absence of an anatomical change, psychiatric disorders such as trichotillomania may lead to the formation of trichobezoars in the stomach. The so-called Rapunzel syndrome is the extension of the bezoars down to the duodenum and the jejunum, which is a rare condition. In this paper, a 13-year-old patient with trichotillomania is reported, who was admitted to our clinic with nausea, vomiting, and fatigue complaints, in whom a giant trichobezoar was identified, which completely filled the stomach and duodenum, without causing obstruction.

Ozdemir, Hakan; Ozdemir, Zehra U; Sahiner, Ibrahim T; Senol, Metin

2012-01-01

230

An Unusual Case Report of Rapunzel Syndrome Trichobezoar in a 3-Year-Old Boy  

PubMed Central

Rapunzel Syndrome is a rare trichobezoar, involving strands of swallowed hair extending as a tail through the duodenum, beyond the stomach. Trichobezoar usually occur in patients with history of trichotillomania, characterized by compulsive behavioral disorder of pulling own hairs, combined with trichophagia that consists of ingesting that hairs. It typically occurs in stomach and rarely affects the small intestine. Trichobezoars are more common in adolescent females. Common presentation is gastrointestinal tract obstruction with nausea and vomiting, gut perforation, acute pancreatic necrosis, obstructive jaundice, hypochromic anemia, vitamin B12 deficiency, weight loss, an abdominal mass, or other serious problems. Intestinal obstruction due to trichobezoar is extremely rare. We are here reporting a large trichobezoar in a 3-year-old male child who presented to the emergency department with thread protruding from mouth with no sign of hair loss on body.

Jain, Manish; Solanki, Sohan Lal; Bhatnagar, Ankur; Jain, Pavan Kumar

2011-01-01

231

Vagal nerve stimulation in children under 12 years old with medically intractable epilepsy.  

PubMed

OBJECTIVE: This study aims to assess the efficacy and safety of vagal nerve stimulation (VNS) in children less than 12 years old operated on at the University Hospital Wales. METHOD: Retrospective review of patients undergoing VNS insertion, over a 3-year period, was undertaken. All children had a minimum follow-up period of 2 years. Sixteen patients were identified via the paediatric epilepsy surgery database. A case note review and telephone evaluation was conducted. Seizure frequency using the McHugh classification was the primary outcome measure, with anti-epileptic drug (AED) use as a secondary outcome measure. RESULTS: There were 10 males and 6 females. The mean time with epilepsy prior to surgery was 5.7 years and the mean age at the time of surgery was 7.6 years. Overall, nine (56 %) children experienced a reduction in their seizure frequency of 50 % or more. Of these, four (25 %) had a reduction of more than 80 %. Seven children (44 %) had no reduction in their seizure frequency, although two of these patients reported benefit regarding seizure control and post-ictal recovery. The VNS system was removed in two patients due to infection and no benefit, respectively. Half of the cohort (50 %) reduced the number of anti-epileptic drugs post-surgery, and there was an overall mean reduction of AED of 0.5. CONCLUSION: This study suggests that VNS is a safe and effective adjuvant therapy in children under 12 years old, with over half reporting significant benefit. Further studies are needed to enable preoperative selection of patients in order to maximise the potential benefit. PMID:23681311

Healy, S; Lang, J; Te Water Naude, J; Gibbon, F; Leach, P

2013-05-17

232

28. Graffiti in north cells: '20 years old 4315 CD ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. Graffiti in north cells: '20 years old 4315 C-D Mamoru Yoshimoto 5/24/45 180 days Kumamoto'; '18 ' ' years old 1406-A Haruo Yokoi 6/17/45 270 days Nagoya'; '31 ' ' years old 5604-B Masaki Nishii 5/24/45 180 days Kumamoto'; '19 ' ' years old 1806-B Masaharu Yoshida 5/24/45 180 days Hiroshima'; 135mm lens with electronic flash illumination. - Tule Lake Project Jail, Post Mile 44.85, State Route 139, Newell, Modoc County, CA

233

Twelve-Year-Old Girl with Primary Biliary Cirrhosis  

PubMed Central

Primary biliary cirrhosis (PBC) is a slowly progressive cholestatic liver disease of autoimmune etiology. The initial presentation of PBC is varies from asymptomatic, abnormal liver biochemical tests to overt cirrhosis. Unlike other autoimmune liver diseases, PBC has rarely been reported in childhood. We report a case of primary biliary cirrhosis in a 12-year-old girl. In addition to characteristic histology features, strongly positive antimitochondrial antibodies, increased liver enzyme levels, increased serum quantitative immunoglobulin M levels, and cholestasis were discovered. She had been treated with ursodeoxycholic acid. In the world literature, we found only few pediatric patients of primary biliary cirrhosis. Aetiology, pathogenesis, the long-term natural history, and prognosis remain obscure. Due to increased awareness of early-onset PBC, rather than typical older ones, further pediatric cases may be discovered.

Kitic, Ivana; Boskovic, Aleksandra; Stankovic, Ivica; Prokic, Dragan

2012-01-01

234

[Ramsay Hunt syndrome in a 13-year-old boy].  

PubMed

We describe a formerly healthy 13-year-old boy who was admitted with symptoms of epiphora from his left eye over a period of four days and of left-sided peripheral facial palsy for one day. There was no history of trauma or tick bites. Cutaneous vesicles were observed in the ipsilateral ear. Pleocytosis was found and positive polymerase chain reaction for varicella zoster virus was obtained in samples from the vesicles and the cerebrospinal fluid. A magnetic resonance imaging confirmed neuritis of the left facial nerve. The patient was treated with a combination of aciclovir and prednisolone for ten days. On follow-up one week later, full recovery had been obtained. PMID:23428268

Andersen, Lise Bols; Christensen, Ann-Margrethe R; Thelle, Thomas

2013-02-18

235

A 46-year-old man with excruciating shoulder pain.  

PubMed

A 46-year-old man with no significant medical history presented to his local emergency department complaining of excruciating right shoulder pain. The patient was in his usual state of excellent health until 4 days prior, when right shoulder pain developed while he was using a chainsaw to cut wood. The next day, flu-like symptoms developed with fevers, chills, and headache. An MRI revealed that the right pectoralis major was torn from its attachment to the acromion. His shoulder pain intensified despite treatment with hydrocodone and acetaminophen, and the flu-like symptoms progressed over the next 2 days. Finally, on the day of hospital admission, he was weak and unable to arise out of bed. He was taken by family members to the local emergency department. PMID:15764791

Olafsson, Eric J; Zeni, Tallal; Wilkes, David S

2005-03-01

236

Spontaneous Coronary Artery Dissection in a Male Patient with Takayasu's Arteritis and Antiphospholipid Antibody Syndrome  

PubMed Central

We present a case of a 34-year-old male who presented to the emergency ward with fever and abdominal pain. The diagnosis of Takayasu's arteritis and also antiphospholipid syndrome was made during an imaging workup of deep-vein thrombosis. A spontaneous coronary artery dissection was revealed in coronary CT angiography requested for chest pain and dyspnea. The patient was treated medically and discharged on close followup. The concurrence of spontaneous coronary artery dissection with antiphospholipid syndrome and Takayasu's arteritis has not been reported in the previous literature. The possibility of a spontaneous coronary artery dissection should be considered in patients presenting with both diseases.

Gerede, Demet Menekse; Yuksel, Bagdagul; Tutar, Eralp; Kucuksahin, Orhan; Uzun, Caglar; Atasoy, Kayhan Cetin; Duzgun, Nursen; Bengisun, Ugur

2013-01-01

237

Medical Care and Your 1- to 2-Year-Old  

MedlinePLUS

Medical Care and Your 1- to 2-Year-Old KidsHealth > Parents > Growth & Development > Medical Care > Medical Care and Your 1- to 2-Year-Old Print A A A Text Size ... Recognizing his or her own name? By age 2, following simple instructions? Saying a few words? Combining ...

238

Medical Care and Your 2- to 3-Year-Old  

MedlinePLUS

Medical Care and Your 2- to 3-Year-Old KidsHealth > Parents > Doctors & Hospitals > Doctor & Hospital Visits > Medical Care and Your 2- to 3-Year-Old Print A A A ... feel kids should have a first exam between 2 and 3 years of age — earlier if problems ...

239

Talocalcaneal coalition in a 15 year old female basketball player.  

PubMed

This case reports an adolescent athlete with activity related chronic bilateral dorsal foot pain and stiffness. A 15 year old competitive female basketball player presented to a chiropractor subsequent to an unsuccessful course of conservative treatment for posterior tibial dysfunction. The patient's plain films were incorrectly read as normal and a CT scan obtained by the radiologist called the findings bilateral osteoarthritis. The patient was awaiting a referral to a rheumatologist at the time of initial consultation with the chiropractor. Examination revealed limited subtalar mobility and review of the images revealed bilateral non-osseous talocalcaneal coalition. The patient was subsequently directed to a pediatric orthopedic surgeon and is scheduled for a resection of the coalition. Primary care practitioners should be aware of this uncommon, but not rare, variable clinical presentation as misdiagnosis and mismanagement could lead to suboptimal patient outcomes. To our knowledge this is the first case report of a patient with tarsal coalition published in chiropractic literature. In addition, this case is the first to report radiographic evidence of chronic mechanical stress to the second metatarsal associated with tarsal coalition. PMID:21120013

Schenkel, David; Degraauw, Jennifer; Degraauw, Christopher

2010-12-01

240

Gender differences in respiratory symptoms in 19-year-old adults born preterm  

Microsoft Academic Search

OBJECTIVE: To study the prevalence of respiratory and atopic symptoms in (young) adults born prematurely, differences between those who did and did not develop Bronchopulmonary Disease (BPD) at neonatal age and differences in respiratory health between males and females. METHODS: Design: Prospective cohort study. Setting: Nation wide follow-up study, the Netherlands. Participants: 690 adults (19 year old) born with a

Elianne JLE Vrijlandt; Jorrit Gerritsen; H Marike Boezen; Eric J Duiverman

2005-01-01

241

Risk Factors for Speech Delay of Unknown Origin in Three-Year-Old Children.  

ERIC Educational Resources Information Center

Compared 100 three-year-olds with speech delay of unknown origin and 539 same-age peers with respect to 6 speech disorder variables; also examined abnormal hearing in a subset of 279 children. Found significant odds ratios only for low maternal education, male sex, and positive family history; a child with all 3 factors was 7.71 times as likely to…

Campbell, Thomas F.; Dollaghan, Christine A.; Rockette, Howard E.; Paradise, Jack L.; Feldman, Heidi M.; Shriberg, Lawrence D.; Sabo, Diane L.; Kurs-Lasky, Marcia

2003-01-01

242

Hepatocellular adenoma in a 12-year-old crossbred German shepherd dog  

PubMed Central

Abstract A 12-year-old, neutered male crossbred German shepherd presented with lethargy, inappetence, vomiting, and diarrhea. Bile duct carcinoma was diagnosed by cytological analysis of samples obtained by ultrasound-guided fine-needle aspiration. After surgical excision of the mass, the histologic diagnosis was hepatocellular adenoma.

2004-01-01

243

Personal and Social Correlates of the "Closed Mind" among 16-Year-Old Adolescents in England.  

ERIC Educational Resources Information Center

|Compares what is known about key personal and social correlates of scores on Rokeach dogmatism scales with findings from a new study of English 16-year-old pupils. Demonstrates that higher dogmatism scores are associated with lower IQ scores, lower social-class backgrounds, higher neuroticism scores, higher lie-scale scores, and being male. (DSK)|

Francis, Leslie J.

1997-01-01

244

Lap-belt syndrome: management of aortic intimal dissection in a 7-year-old child with a constellation of injuries  

Microsoft Academic Search

We present a case of lap-belt motor vehicle injury in a 7-year-old male who was admitted with abdominal ecchymoses and pain\\u000a with associated aortic intimal flap, bowel injury, hemoperitoneum, and retroperitoneal hematoma at initial imaging with CT.\\u000a Most of these findings were confirmed at subsequent laparotomy, and the patient underwent operative repair of bowel injuries.\\u000a His aortic intimal flap was

Paritosh C. Khanna; Patricia Rothenbach; Philip C. Guzzetta; Dorothy I. Bulas

2007-01-01

245

Puzzlemaking and Part-Whole Perception of Two-Year-Old and Four-Year-Old Children  

ERIC Educational Resources Information Center

The relationship between preschoolers' puzzlemaking strategies and part-whole perception was investigated in the present study. Forty-eight two year olds and 48 four year olds were randomly selected from eight licensed childcare centers. Puzzlemaking strategies (image, form, color, and trial and error) were measured by performance in the…

Montford, Emily I. Purvis; Readdick, Christine A.

2008-01-01

246

Ductal carcinoma in situ in a 25-year-old man presenting with apparent unilateral gynecomastia  

PubMed Central

Ductal carcinoma in situ (dcis) in a young man is rarely reported. Our patient, a 25-year-old man, presented with apparent symptomatic unilateral gynecomastia. He has a strong history of cancer on both the maternal and paternal sides of his family, including breast and lung (maternal) and melanoma, colon, and pancreatic (paternal). His mother tested negative for BRCA1 and BRCA2. There is no information on paternal genetic testing. The patient was treated with left subcutaneous mastectomy. Upon histologic review of the sample, concurrent gynecomastia and dcis were discovered. To date, only 4 cases of gynecomastia and dcis have been described in younger male patients. Because only 30%–50% of patients with dcis eventually develop invasive cancer in the subsequent 10–20 years, dcis prevalence in the general population may be higher than predicted. This case underscores the importance of family history in any patient presenting with a breast mass. Patients must be made aware of the risk, however small it may be, and physicians must remain cautious of cancer in young men with gynecomastia.

Coroneos, C.J.; Hamm, C.

2010-01-01

247

Ductal carcinoma in situ in a 25-year-old man presenting with apparent unilateral gynecomastia.  

PubMed

Ductal carcinoma in situ (DCIS) in a young man is rarely reported. Our patient, a 25-year-old man, presented with apparent symptomatic unilateral gynecomastia. He has a strong history of cancer on both the maternal and paternal sides of his family, including breast and lung (maternal) and melanoma, colon, and pancreatic (paternal). His mother tested negative for BRCA1 and BRCA2. There is no information on paternal genetic testing.The patient was treated with left subcutaneous mastectomy. Upon histologic review of the sample, concurrent gynecomastia and DCIS were discovered. To date, only 4 cases of gynecomastia and DCIS have been described in younger male patients. Because only 30%-50% of patients with DCIS eventually develop invasive cancer in the subsequent 10-20 years, DCIS prevalence in the general population may be higher than predicted. This case underscores the importance of family history in any patient presenting with a breast mass. Patients must be made aware of the risk, however small it may be, and physicians must remain cautious of cancer in young men with gynecomastia. PMID:20697526

Coroneos, C J; Hamm, C

2010-08-01

248

Prurigo nodularis in a 9-year-old girl.  

PubMed

A 9-year-old African-American female with a known history of atopic dermatitis presented for evaluation of an intensely pruritic nodular rash on both upper and lower extremities, buttocks, and lower abdomen for more than 1 year. The patient had been treated with several medium-potency topical steroids and antipruritics without appreciable improvement. After considering and excluding other differential diagnoses, the diagnosis of prurigo nodularis (PN) in association with atopic dermatitis was made. Prurigo nodularis usually occurs in middle-aged and older persons and is rarely seen in the pediatric population. The onset of PN in the case presented is considerably earlier than what has been described in literature. The etiology of the disorder is unknown. The management of prurigo nodularis is usually challenging for both patients and treating physicians. Frequently, combinations of several medications or modalities are used in an attempt to control disease activity. Overall, PN is a benign condition in children, particularly when it is associated with atopic dermatitis. It does not increase mortality; however, it can cause significant morbidity in untreated patients. PMID:18648078

Amer, Ahdi; Fischer, Howard

2008-07-22

249

Primary Cardiac Angiosarcoma in a 25-Year-Old Man  

PubMed Central

Primary cardiac tumors do not occur frequently, and only one quarter of them, chiefly sarcomas, are malignant. Patients with angiosarcoma typically have a shorter survival time than do patients with other sarcomas, and the prognosis for survival depends strictly on the stage of the disease at the time of diagnosis and the possibility of complete surgical excision. Chemotherapy and radiotherapy have well-established postoperative roles because of the high probability of metastasis. We report the case of a 25-year-old man who presented with pericardial effusion and echocardiographic evidence of an intracavitary right atrial mass but without the bulky, infiltrative growth typical of this location of the disease. Malignancy was suggested by the clinical presentation, the location of the mass in the right side of the heart, and the absence of conditions favoring thrombus formation. After complete surgical excision, the mass was confirmed to be an angiosarcoma. Conventional adjuvant chemotherapy and maintenance therapy with inhibitors of CD117 (c-kit) and vascular endothelial growth factor relieved the patient's clinical symptoms and enabled his long-term, disease-free survival. In addition to reporting this case, we discuss aspects of the diagnosis and treatment of angiosarcoma.

Bellitti, Renato; Buonocore, Marianna; De Rosa, Nicolina; Covino, Franco Enrico; Casale, Beniamino; Sante, Pasquale

2013-01-01

250

Clustering of Health-Related Behaviors among 18YearOld Australians  

Microsoft Academic Search

Background.Few studies among young adults have examined clustering of health behaviors affecting risk for lifestyle diseases.Methods.Smoking, alcohol consumption, physical activity, and diet were examined among Australian 18-year-olds (301 males, 282 females) initially recruited at the age of 9 years from 26 schools. Association analysis was used to recognize behavior clustering.Results.Fat intake was greater among male smokers than nonsmokers (36% energy

V. Burke; R. A. K. Milligan; L. J. Beilin; D. Dunbar; M. Spencer; E. Balde; M. P. Gracey

1997-01-01

251

Sigmoid Volvulus in 16-year-old Boy with an Associated Anomalous Congenital Band.  

PubMed

Sigmoid volvulus, a condition generally seen in debilitated elderly patients, is extremely rare in the pediatric age group. Frequent predisposing conditions that accompany pediatric sigmoid volvulus include intestinal malrotation, omphalomesenteric abnormalities, Hirschsprung's disease, imperforate anus and chronic constipation. A 16-year-old previously healthy African American male presented with a 12 hour history of sudden onset abdominal pain and intractable vomiting. CT was consistent with sigmoid volvulus. A contrast enema did not reduce the volvulus, but it was colonoscopically reduced. Patient condition initially improved after colonoscopy, but he again became distended with abdominal pain, so he was taken to the operating room. On exploratory laparotomy, a band was discovered where the mesenteries of the sigmoid and small bowel adhered and created a narrow fixation point around which the sigmoid twisted. A sigmoidectomy with primary anastomosis was performed. The diagnosis of sigmoid volvulus may be more difficult in children, with barium enema being the most consistently helpful. Seventy percent of cases do not involve an associated congenital problem, suggesting that some pediatric patients may have congenital redundancy of the sigmoid colon and elongation of its mesentery. The congenital band found in our patient was another potential anatomic factor that led to sigmoid volvulus. Pediatric surgeons, accustomed to unusual problems in children, may thus encounter a condition generally found in the debilitated elderly patient. PMID:24165246

Albert, Ann A; Nolan, Tracy L; Weidner, Bryan C

2013-11-01

252

Primary retroperitoneal mucinous cystadenocarcinoma in a male patient: a case report  

PubMed Central

In the literature, 51 cases of primary retroperitoneal mucinous cystadenocarcinoma have been published. We report the fourth case occurring in a male patient. The 42-year-old patient presented with multiple retroperitoneal cystic masses causing abdominal discomfort without alteration of the global clinical state. The masses were totally removed by a two-stage surgery. No other treatment has been introduced. After a follow-up of 6 months, the patient is disease-free. This rare tumor most likely arises from the mucinous metaplasia of peritoneal inclusion cysts rather than from ectopic ovarian tissue or ovarian teratomas. The occurrence of such a tumor in a male patient supports this theory. Preoperative diagnosis is mostly difficult. Clinical behavior and treatment are still controversial.

Hrora, Abdelmalek; Jallal, Houda; Sabbah, Farid; Benamer, Abdessalam; Alaoui, Mouna; Raiss, Mohamed; Ahallat, Mohamed

2009-01-01

253

Feeding and Nutrition: Your Two-Year-Old  

MedlinePLUS

... Old Ages & Stages Listen Feeding and Nutrition: Your Two-Year-Old Article Body By age two, your toddler should be eating three healthy meals a day , plus one or two snacks. He can eat the same food as ...

254

Medical Care and Your 13- to 18-Year-Old  

MedlinePLUS

Medical Care and Your 13- to 18-Year-Old KidsHealth > Parents > Doctors & Hospitals > Doctor & Hospital Visits > Medical ... physical activity Back Continue If You Suspect a Medical Problem Parents or other caregivers should receive health ...

255

Medical Care and Your 4- to 5-Year-Old  

MedlinePLUS

Medical Care and Your 4- to 5-Year-Old KidsHealth > Parents > Doctors & Hospitals > Doctor & Hospital Visits > Medical ... locked at all times. If You Suspect a Medical Problem Parents often can tell by their child's ...

256

The pharmacologic stability of 35-year old theophylline  

Microsoft Academic Search

The propensity to preserve and to hoard drugs over the years at home is a well-known phenomenon and offers the possibility for intentional and accidental drug poisoning in man. We report a case of acute theophylline poisoning in an 80-year old women after ingestion of ‘Asthmo-Kranit1 ’, a 35-year old combined preparation containing theophylline and aminopyrine as the main ingredients.

R Regenthal; D Stefanovic; T Albert; H Trauer; T Wolf

2002-01-01

257

Isolated aglossia in a six year old child presenting with impaired speech: a case report  

PubMed Central

Introduction The most mobile organ of the body, the tongue is associated with various congenital anomalies; most of which are in association with many other systemic abnormalities. Rarely do they occur in isolation. Isolated aglossia, that we presented, is one of the more rare presentations. Case presentation Our patient is a 6-year-old male child of Asiatic origin from Kashmir (India), who was physically well built and mentally sound and presented with history of impaired speech. The patient had normal velopharangeal competence but absence of tongue which was replaced by a small mucus membrane projection near the floor of oropharangeal isthmus. The patient had no difficulty in feeding or taste sensation but he was unable to pronounce lingual consonants. Conclusion Isolated aglossia is very rare condition explained on the basis of growth failure of lateral lingual swellings and tubercular impar. Such patients do not usually need reconstruction of tongue; as feeding, swallowing and taste sensations are usually intact and speech cannot be improved by reconstruction. However, malocclusion of teeth needs to be taken care of.

Zaroo, Mohammad Inam; Wani, Adil Hafeez; Darzi, Mohammad Ashraf; Bashir, Shiekh Adil; Bijli, Akram Hussain; Rashid, Shafaq

2009-01-01

258

[A ten-year-old girl with dizziness].  

PubMed

Childhood dizziness may take many forms; most often it presents as acute short-lived spinning attacks associated with headaches and nausea and less frequently as long-lasting symptoms with unsteadiness. Migrainous vertigo and middle ear infections are considered to be the most common causes of childhood dizziness, while head injury and pathology of the central nervous system are less common causes. We present a case history of a 10-year-old girl with acute positional vertigo attacks. Investigations and treatment demonstrated that this patient had canalithiasis variant Benign Paroxysmal Positional Vertigo (BPPV) in the lateral canal of the inner ear. The conventional view among many vestibular specialists is that childhood BPPV does not exist. We have demonstrated the opposite, and propose that childhood BPPV is more widespread than previously thought. We believe that children often spontaneously reposition dislodged otoconia through normal childhood play activities (e. g. tumbling, running, jumping, rolling etc.) thus avoiding the need to present for treatment with Epley and/ or Barbecue manoeuvres. PMID:19337333

Skatvedt, Olav; Mjøen, Svein; Sealy, Alan

2009-03-26

259

Cosmetic clitoridectomy in a 33-year-old woman.  

PubMed

The Female Genital Mutilation Act (2003) in England allows for mental health exceptions for cosmetic surgery resulting from perceived abnormality. Similar legislation exists in other countries. There are no reported cases of clitoridectomy for cosmetic reasons or any discussion in the literature of mental health exceptions to the Act. This is a single case report on a 33-year-old married, heterosexual woman who had already had a cosmetic labiaplasty and was seeking a clitoridectomy for aesthetic reasons. At assessment, there were no psychiatric contra-indications or unrealistic expectations and the patient proceeded with a clitoridectomy. At 9 and 22 months follow-up, she was reassessed and was very pleased with the outcome. There were improvements in the satisfaction with her genital appearance, sexual satisfaction, and quality of life related to body image. Assessments for cosmetic clitoridectomy will continue to be rare, but this case may provide some guidance for practitioners who are confronted with such requests for body modification. However there remains only limited understanding of the motivation for such a request. PMID:21837517

Veale, David; Daniels, Joe

2011-08-12

260

Pulmonary adiaspiromycosis in a two year old girl.  

PubMed Central

A case of disseminated bilateral pulmonary adiaspiromycosis is reported in a two year old Finnish girl. She recovered from this rare infection after treatment with amphotericin B. She is the first human case of adiaspiromycosis in Scandinavia and she is the youngest child with this disease reported so far. Electron microscopy showed that the three layers of the spore wall were not typical; rather, there seemed to be a gradual transition between the main wall zones, which may be split into an indefinite number of thin layers. Varying numbers and thicknesses were seen with different staining methods, and in different spores. Diagnosis relies on recognition of the fungus in a pulmonary biopsy specimen, because there are no reliable serological tests and culture of the fungus is time consuming and not always successful. It was thought that this patient had become infected as a result of contact with soil dust containing the spores in the yard surrounding her home, and as a result of her mother's work in a large garden shop. Images

Nuorva, K; Pitkanen, R; Issakainen, J; Huttunen, N P; Juhola, M

1997-01-01

261

Malignant Blue Nevus with Lymph Node Metastases in Five-Year-Old Girl  

Microsoft Academic Search

We report an unusual case of a malignant blue nevus in a five-year-old girl, which turned out to be ma- lignant only after the development of lymph node metastases three years after the excision of the pri- mary tumor on the patient's cheek. A functional bilateral neck dissection was performed and the patient is alive with no evidence of disease

Marko Hoèevar; Lidija Kitanovski

262

Short-term and long-term results of speech improvement after surgery for velopharyngeal insufficiency with pharyngeal flaps in patients younger and older than 6 years old: 10-year experience.  

PubMed

Velopharyngeal insufficiency (VPI) is a well-known cause for hypernasality. To overcome this problem, the authors use a static surgical technique: a cranially or caudally based flap. In 93 patients, the results of this technique on speech (hypernasality, nasal air escape, articulation) and velopharyngeal function were evaluated over a period of at least 1 year. In 53 patients, pharyngoplasty flaps were based caudally. In 40 patients, pharyngoplasty flaps were based cranially. The patients were age 2.5 to 24.5 years, with a mean of 5.5 years (SD: 4 years and 2 months). Improvement was found in almost all patients. The patients who underwent surgery when they were younger than age 6 significantly improved better then the patients who were treated when they were older than age 6. There were no differences in outcome between cranially based and caudally based flaps. There were also no differences between patients with plain VPI and patients with VPI (e.g., Pierre Robin sequence and Shprintzen). PMID:12545103

Meek, Marcel F; Coert, J Henk; Hofer, Stefan O P; Goorhuis-Brouwer, Sieneke M; Nicolai, Jean-Philipe A

2003-01-01

263

Deformities due to Leprosy in Children under Fifteen Years Old as an Indicator of Quality of the Leprosy Control Programme in Brazilian Municipalities  

PubMed Central

The present study aims at analysing the degree of deformity in leprosy cases diagnosed in children under 15 years old and its relationship with operational and epidemiological factors. This epidemiological cross-sectional study was carried out at municipalities of three microregions in a Brazilian hyperendemic area. Data between 1998 and 2010 was collected from the Information System for Notifiable Diseases database. The average coefficient of detection was 32.96/100.000 inhabitants; 7.61% of new cases were diagnosed in children under 15 years old; 5% in this age group were grade 2 deformity at diagnosis. Prevalence of leprosy cases in children under 15 years old with deformity was higher in males (PR = 2.65;P = 0.032; CI 95%: 1.09–6.45) and in multibacillary patients (PR = 14.68;P < 0.001; CI 95%: 3.54–60.87) and lower when the detection mode was passive (PR = 0.73,P = 0.47, CI 95%: 0.31–1.73). Such context suggests high transmissibility and early exposure to Mycobacterium leprae since a lot of cases were diagnosed in children under fifteen years old and the incubation period of the leprosy bacillus varies from 02 to 07 years. This situation contributes to maintaining the chain of disease transmission in the area and indicates that health care services should intensify leprosy control.

Lana, Francisco Carlos Felix; Fabri, Angelica da Conceicao Oliveira Coelho; Lopes, Fabiana Nascimento; Carvalho, Ana Paula Mendes; Lanza, Fernanda Moura

2013-01-01

264

Deformities due to Leprosy in Children under Fifteen Years Old as an Indicator of Quality of the Leprosy Control Programme in Brazilian Municipalities.  

PubMed

The present study aims at analysing the degree of deformity in leprosy cases diagnosed in children under 15 years old and its relationship with operational and epidemiological factors. This epidemiological cross-sectional study was carried out at municipalities of three microregions in a Brazilian hyperendemic area. Data between 1998 and 2010 was collected from the Information System for Notifiable Diseases database. The average coefficient of detection was 32.96/100.000 inhabitants; 7.61% of new cases were diagnosed in children under 15 years old; 5% in this age group were grade 2 deformity at diagnosis. Prevalence of leprosy cases in children under 15 years old with deformity was higher in males (PR = 2.65;P = 0.032; CI 95%: 1.09-6.45) and in multibacillary patients (PR = 14.68;P < 0.001; CI 95%: 3.54-60.87) and lower when the detection mode was passive (PR = 0.73,P = 0.47, CI 95%: 0.31-1.73). Such context suggests high transmissibility and early exposure to Mycobacterium leprae since a lot of cases were diagnosed in children under fifteen years old and the incubation period of the leprosy bacillus varies from 02 to 07 years. This situation contributes to maintaining the chain of disease transmission in the area and indicates that health care services should intensify leprosy control. PMID:23577038

Lana, Francisco Carlos Félix; Fabri, Angélica da Conceição Oliveira Coelho; Lopes, Fabiana Nascimento; Carvalho, Ana Paula Mendes; Lanza, Fernanda Moura

2013-03-19

265

Degeneration of skeletal muscle fibers in the rat administrated carbon tetrachloride: similar histological findings of the muscle in a 64-year-old patient of LC with muscle cramp.  

PubMed

It is well known that painful muscle cramps occur frequently in patients with advanced liver cirrhosis (LC). Although many studies discuss the pathophysiological causes of these muscle cramps in various conditions, the results are not clear as far as the cause associated to LC is concerned. In order to investigate the cause of muscle cramps in LC, we examined the histological findings of skeletal muscle fibers in LC rat model and in a patient with LC. LC (n=9) was induced in rats by chronic carbon tetrachloride administration. The histological findings of skeletal muscle tissues from the lower leg in LC rats and those of the upper arm in a patient with LC were compared. The degenerated muscle fibers and centronucleus in LC rats were similar to the opaque fibers frequently observed in myotonic dystrophy with severe muscle rigidity in patients with LC. In conclusion, results of this study suggest that one of the causes for muscle cramps in patients with LC is due to skeletal muscle fiber degeneration. Therefore, histological observation of skeletal muscle fibers should be considered in the treatment of painful muscle cramps. PMID:12479935

Matsuzaki, Yasushi; Miyazaki, Teruo; Ohkoshi, Norio; Miyakawa, Shunpei; Bouscarel, Bernard; Tanaka, Naomi

2002-12-01

266

Can bilingual two-year-olds code-switch?  

PubMed

Sociolinguists have investigated language mixing as code-switching in the speech of bilingual children three years old and older. Language mixing by bilingual two-year-olds, however, has generally been interpreted in the child language literature as a sign of the child's lack of language differentiation. The present study applies perspectives from sociolinguistics to investigate the language mixing of a bilingual two-year-old acquiring Norwegian and English simultaneously in Norway. Monthly recordings of the child's spontaneous speech in interactions with her parents were made from the age of 2;0 to 2;7. An investigation into the formal aspects of the child's mixing and the context of the mixing reveals that she does differentiate her language use in contextually sensitive ways, hence that she can code-switch. This investigation stresses the need to examine more carefully the roles of dominance and context in the language mixing of young bilingual children. PMID:1429952

Lanza, E

1992-10-01

267

Four years old, one eye, pars planitis and cataract: surgical challenges give challenging surprises.  

PubMed

Pars planitis (PP) is an intermediate form of uveitis, which, if left untreated, can result in vision loss. Although phacoemulsification with IOL implantation in eyes with PP often results in improved vision, it represents a surgical challenge due to inflammatory sequelae and the possibility of postoperative complications. This case report describes a 4-year-old male who was admitted for poor visual acuity and severe photophobia. The patient previously received vitreo-retinal surgery on his right eye due to an 'unknown disease'. Ophthalmological evaluation revealed NLP, pupillary seclusion and band keratopathy in the right eye; echographic scans revealed funnel retinal detachment. The left eye had a visual acuity of CF at 1 foot, minimal band keratopathy, posterior synechiae and the following echographic findings: abundant vitreous opacities and increased chorioretinal thickness (1.6 mm). Complete medical and laboratory assessments found no infectious pathologies. The patient was diagnosed with PP. Anti-inflammatory and immunological therapy was given in order to control inflammation. Within four months, the inflammation was controlled. Slow motion phacoemulsification with iris-retractors was performed. During the surgery, an unexpected challenge was identified: an opaque-vascular retrolental membrane. The membrane was cauterized with diathermy. Primary posterior capsulotomy and membranectomy were performed, followed by a limited anterior vitrectomy. An in-the-bag IOL was implanted successfully, with no postoperative complications, and visual acuity improved to 20/200. PMID:23626571

García-Rojas, Leonardo; Matiz-Moreno, Humberto; Chávez-Mondragón, Eduardo

2013-03-06

268

A case of premature ovarian failure in a 33-year-old woman.  

PubMed

Objective. To assess aetiology of a POF in a 33-year-old woman and, if possible, plan a cure. Design. Case report. Setting. medical genetics diagnostic unit in a university hospital. Patient. A 33-year-old woman with premature ovarian failure (POF). Intervention(s). Genetic counseling, karyotyping, FISH study. Result(s). Turner-like diagnosis. Conclusion(s). Most cases of POF remain idiopathic. Turner syndrome can occur in very different phenotypes; cytogenetic and molecular profiling can provide a definitive diagnosis in cases with nonclassical phenotype. PMID:23509644

Colao, Emma; Granata, Teresa; Vismara, Marco F M; Bombardiere, Francesco; Nocera, Donatella; Luciano, Elisa; Perrotti, Nicola; Malatesta, Paola

2013-01-29

269

A Case of Premature Ovarian Failure in a 33-Year-Old Woman  

PubMed Central

Objective. To assess aetiology of a POF in a 33-year-old woman and, if possible, plan a cure. Design. Case report. Setting. medical genetics diagnostic unit in a university hospital. Patient. A 33-year-old woman with premature ovarian failure (POF). Intervention(s). Genetic counseling, karyotyping, FISH study. Result(s). Turner-like diagnosis. Conclusion(s). Most cases of POF remain idiopathic. Turner syndrome can occur in very different phenotypes; cytogenetic and molecular profiling can provide a definitive diagnosis in cases with nonclassical phenotype.

Colao, Emma; Granata, Teresa; Vismara, Marco F. M.; Bombardiere, Francesco; Nocera, Donatella; Luciano, Elisa; Perrotti, Nicola; Malatesta, Paola

2013-01-01

270

Risk Factors for Speech Delay of Unknown Origin in 3YearOld Children  

Microsoft Academic Search

One hundred 3-year-olds with speech delay of unknown origin and 539 same-age peers were compared with respect to 6 variables linked to speech disorders: male sex, family history of developmental communication disorder, low maternal education, low socioeconomic status (indexed by Medicaid health insurance), African American race, and prolonged otitis media. Abnormal hearing was also examined in a subset of 279

Thomas F. Campbell; Christine A. Dollaghan; Howard E. Rockette; Jack L. Paradise; Heidi M. Feldman; Lawrence D. Shriberg; Diane L. Sabo; Marcia Kurs-Lasky

2003-01-01

271

Ventilation-limited exercise capacity in a 59-year-old athlete  

Microsoft Academic Search

Aerobic exercise performance may be limited by the respiratory system in fit elderly adults whose lungs undergo the normal ageing process or who develop lung diseases but can maintain high pulmonary blood flows and ventilatory requirements. Here we describe a 59-year-old athlete demonstrating high aerobic exercise performance limited by his relatively low ventilatory capacity.The male hobby cyclist (59 years, 176cm,

M. Burtscher; M. Schocke; R. Koch

2011-01-01

272

A Two-Year-Old with Rickets: Diet History, Treatment and Follow-Up  

Microsoft Academic Search

AJ, a 2-year-old African-American male, was referred to a nutrition and gastroenterology clinic with the diagnosis of rickets and iron deficiency anemia, both of which were secondary to poor nutrition. All of the classic signs of rickets were present: frontal bossing, rachitic rosary, enlarged joints, and bowed legs with the latter condition making it impossible for AJ to walk without

K. R. Kramer; S. M. Phillips; J. Radcliffe

1998-01-01

273

Recurrent ventriculoperitoneal shunt pseudocyst in a nine-year-old girl  

Microsoft Academic Search

Summary A case of a ventriculoperitoneal shunt pseudocyst in a 9-year-old girl diagnosed using computed tomography is reported. Two attempts at relocation of the shunt failed to prevent reaccumulation of cerebrospinal fluid. A ventriculoatrial shunt was then performed with a successful outcome. Such pseudocysts should be part of the differential diagnosis of abdominal processes in patients with ventriculoperitoneal shunts. If

F. J. Baumgartner; T. C. Moore; J. Mitchner

1990-01-01

274

Beginning psychoanalysis of a 16 year old autistic girl: the first three months.  

PubMed

This clinical report attempts to show some aspects of the first three months of analysis with a 16 year old autistic girl with some conceptualization of the technical difficulties of instituting psychoanalysis with such a patient, as well as some conceptualizations of the material itself. PMID:519631

Eyre, D P

1979-11-01

275

Uncorrected tetralogy of fallot in a 25-year old nigerian african.  

PubMed

Tetralogy of Fallot is the most common form of cyanotic congenital heart disease. Survival after the age of 12 years without corrective surgery is rare. We present the case of a 25 year-old man with uncorrected tetralogy of Fallot. Possible reasons for the longetivity in this patient are left ventricular hypertrophy and systemic to pulmonary shunting through internal mammary arteries. PMID:21769263

Ojji, Dike B; Babalola, Akinola O; Falase, Ayodele O

2011-04-27

276

Uncorrected Tetralogy of Fallot in a 25-Year Old Nigerian African  

PubMed Central

Tetralogy of Fallot is the most common form of cyanotic congenital heart disease. Survival after the age of 12 years without corrective surgery is rare. We present the case of a 25 year-old man with uncorrected tetralogy of Fallot. Possible reasons for the longetivity in this patient are left ventricular hypertrophy and systemic to pulmonary shunting through internal mammary arteries.

Ojji, Dike B.; Babalola, Akinola O.; Falase, Ayodele O.

2011-01-01

277

A 95-year-old woman with leucocytosis and eosinophilia: anaplastic carcinoma in an ectopic thyroid  

Microsoft Academic Search

A 95-year-old woman had been treated over the past 8 years for progressive dysphagia. When her condition worsened, blood tests revealed the presence of leucocytosis and eosinophilia in the absence of anaemia or thrombocytopenia. Within 11 days of diagnosis, the patient died of respiratory failure. Necropsy showed normal thyroid tissue and an absence of infectious disease. However, an upper mediastinal

Einstein Francisco Camargos; Marcela Basso Pandolfi; Maria Alice V Toledo; Juliana Lima Quintas; Sebastião Moreira-Junior; Ana Emília Borges de Azevedo; Alexandre Cavalca Tavares

2010-01-01

278

Pulmonary artery sling and tracheal bronchus presenting in a 2-year-old child.  

PubMed

Pulmonary artery sling is an incomplete vascular ring, the result of the left pulmonary artery arising from the right pulmonary artery and effectively constricting the airway, and it usually presents within the first weeks to months of life. We report a surgical correction of tracheal stenosis for a two-year-old patient associated with pulmonary artery sling and tracheal broncus. PMID:23196661

Lovett, Marlina; Entrikin, Daniel; Ungerleider, Ross; Ootaki, Yoshio

2012-11-30

279

Tetralogy of Fallot with Dextrocardia and Situs Inversus in a 7-Year-Old Boy  

PubMed Central

Tetralogy of Fallot is one of the most frequently diagnosed congenital cardiac abnormalities; however, its association with dextrocardia and situs inversus is reported only rarely. We report a case of these findings in a 7-year-old boy, describe the patient's postoperative course, and review the medical literature relevant to these combined conditions.

DiLorenzo, Michael; Weinstein, Samuel; Shenoy, Rajesh

2013-01-01

280

Pyloric ulceration and stenosis in a two-year-old thoroughbred filly: a case report  

Microsoft Academic Search

The case of the two year old thoroughbred filly presented here has been diagnosed with and treated for equine gastric ulceration syndrome (EGUS). The results of her examination are documented over a five month period. The patient was finally hospitalised with acute severe colic. Absence of chronic clinical problems common for pyloric stenosis can be attributed to the permanent antiulceration

B. BEZDEKOVA; P. JAHN; J. MEZEROVA

281

Adenomatoid odontogenic tumour in mandible in a 14-year-old boy.  

PubMed

A 14-year-old boy reported with a painless swelling over the right anterior mandible with missing right canine tooth. The lesion was diagnosed as 'central follicular adenomatoid odontogenic tumour' and excised surgically under general anaesthesia. The patient was on a year-long clinical and radiographical follow-up. PMID:23839612

Bhatt, Rohan; Dave, Jay; Nalawade, Triveni M; Mallikarjuna, Rachappa

2013-07-08

282

Complex percutaneous extraction of a 15-year-old atrial lead dislodged into the subclavian vein.  

PubMed

We present a case of a 50-year-old patient with DDD pacing failure who underwent atrial lead extraction. The lead was implanted 15 years ago, and 4 months ago it dislodged into the subclavian vein following a fracture. The lead was removed via the femoral vein approach using a Cook Medical device (Byrd Femoral Workstation, Dotter basket) and pigtail catheter. PMID:22291751

Lelakowski, Jacek; Kutarski, Andrzej; Ma?ecka, Barbara; Majewski, Jacek

2011-03-08

283

Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the ?2 agonist vilanterol administered once daily for 52 weeks in patients >=12 years old with asthma: a randomised trial  

PubMed Central

Background The inhaled corticosteroid fluticasone furoate (FF) in combination with the long-acting ?2 agonist vilanterol (VI) is in development for asthma and chronic obstructive pulmonary disease. Objective To assess the safety and tolerability of FF/VI over 52?weeks in patients with asthma. Methods Patients (aged ?12?years; on inhaled corticosteroid) were randomised (2:2:1) to FF/VI 100/25?µg or FF/VI 200/25?µg once daily in the evening, or fluticasone propionate (FP) 500?µg twice daily. Safety evaluations included adverse events (AEs), non-fasting glucose, potassium, 24-h urinary cortisol excretion, ophthalmic assessments, heart rate and pulse rate. Results On-treatment AEs were similar across groups (FF/VI 66–69%; 73% FP). Oral candidiasis/oropharyngeal candidiasis was more common with FF/VI (6–7%) than FP (3%). Twelve serious AEs were reported; one (worsening hepatitis B on FP) was considered drug related. Statistically significant cortisol suppression was seen with FP compared with both FF/VI groups at Weeks 12 and 28 (ratios [95% CI] to FP ranged from 1.43 [1.11 to 1.84] to 1.67 [1.34 to 2.08]; p?0.006), but not at Week 52 (ratios to FP were 1.05 [0.83 to 1.33] for FF/VI 100/25?µg and 1.09 [0.87 to 1.38] for FF/VI 200/25?µg). No clinically important changes in non-fasting glucose, potassium, QT interval corrected using Fridericia's formula (QTc[F]) or ophthalmic assessments were reported. Pulse rate (10?min post dose [Tmax], Week 52) was significantly increased with FF/VI versus FP (3.4?bpm, 95% CI 1.3 to 5.6; p=0.002 [FF/VI 100/25?µg]; 3.4?bpm, 95% CI 1.2 to 5.6; p=0.003 [FF/VI 200/25?µg]). Mean heart rate (24-h Holter monitoring) decreased from screening values in all groups (0.2–1.1?bpm FF/VI vs 5?bpm FP; Week 52). Conclusions FF/VI (100/25?µg or 200/25?µg) administered once daily over 52?weeks was well tolerated by patients aged ?12?years with asthma. The overall safety profile of FF/VI did not reveal any findings of significant clinical concern. ClinicalTrials.gov NCT01018186

Busse, William W; O'Byrne, Paul M; Bleecker, Eugene R; Lotvall, Jan; Woodcock, Ashley; Andersen, Leslie; Hicks, Wesley; Crawford, Jodie; Jacques, Loretta; Apoux, Ludovic; Bateman, Eric D

2013-01-01

284

Molecular cytogenetic analysis of a ring-Y infertile male patient.  

PubMed

In the present study, we report on the case of a 43-year-old male patient seeking for fertility assistance, who showed a seminal analysis and testicular biopsy of complete azoospermia. Peripheral blood culture for chromosome studies revealed a karyotype of 46 chromosomes with a ring-Y-chromosome that lost the long arm heterochromatin. Molecular analysis of genomic DNA from the patient detected the presence of the sex-determining region of the Y-chromosome (SRY) but the complete absence of regions involved in spermatogenesis (AZFa, AZFb, AZFc). Several molecular markers distributed along the Y-chromosome were tested through PCR amplification, and a breakpoint was established close to the centromere, predicting the deletion of the growth control region, in agreement with the short stature observed in this patient. All results obtained through molecular cytogenetic characterization are in accordance with the clinical features observed in this patient. PMID:17469055

Carvalho, F M; Wolfgramm, E V; Degasperi, I; Verbeno, B M; Vianna, B A; Chagas, F F; Perroni, A M S; Paula, F; Louro, I D

2007-03-09

285

Two-Year-Olds Compute Syntactic Structure On-Line  

ERIC Educational Resources Information Center

|Syntax allows human beings to build an infinite number of new sentences from a finite stock of words. Because toddlers typically utter only one or two words at a time, they have been thought to have no syntax. Using event-related potentials (ERPs), we demonstrated that 2-year-olds do compute syntactic structure when listening to spoken sentences.…

Bernal, Savita; Dehaene-Lambertz, Ghislaine; Millotte, Severine; Christophe, Anne

2010-01-01

286

A 69YearOld Man With Chronic Dizziness  

Microsoft Academic Search

DR PARKER: Mr D is a 69-year-old man troubled by dizziness. He is retired from his job as building superintendent for a public school. He is married, lives in the Boston, Mass, sub- urbs, and has managed Medicare insurance. Mr D dates the onset of his dizziness to 1994, when the symptoms were predominantly vertiginous. He described the sensation as

David A. Drachman

1998-01-01

287

Meaning from Syntax: Evidence from 2-Year-Olds  

ERIC Educational Resources Information Center

|When toddlers view an event while hearing a novel verb, the verb's syntactic context has been shown to help them identify its meaning. The current work takes this finding one step further to reveal that even in the absence of an accompanying event, syntactic information supports toddlers' identification of verb meaning. Two-year-olds were first…

Arunachalam, Sudha; Waxman, Sandra R.

2010-01-01

288

Localized Secondary Erythromelalgia in an 11-Year-Old Boy.  

PubMed

? We report an 11-year-old boy with localized secondary erythromelalgia on his left medial thigh. The episodes responded well to indomethacin and prednisone but recurred after the medications were stopped. The disease was stable after being treated for 5?months. PMID:22612394

Wu, Hui-Hui; Wang, Ming-Jun; Luo, Di-Qing; Lin, Qing

2012-05-21

289

Five-Year-Olds' Fascination for Television: A Comparative Study.  

ERIC Educational Resources Information Center

Compared 5-year-olds' understanding of and fascination with a public service and a commercial television program; also compared parents' and children's perspectives. Found that children were particularly fascinated by sequences containing conflicts and aggression. Sixteen of 20 children chose the commercial channel program. Parents showed insight…

Hake, Karin

2001-01-01

290

Moral and Faith Development in Seventeen-year Old Students.  

ERIC Educational Resources Information Center

Subjects were 50 17 year-old students from a variety of types of schools (parochial, private, public) in two New England areas were interviewed for moral and faith development according to the theories of Kohlberg and Fowler. Socioeconomic level and IQ were highly correlated with faith and moral scores. Experiences of the death of someone close…

Gorman, Margaret

291

Effectiveness of language elicitation tasks with two-year-olds  

Microsoft Academic Search

One unstructured and two structured language sampling conditions were compared to determine the ways in which different types of structure would affect 2-year-olds' productions of the possessor + possession semantic relation. In the unstructured, naturalistic condition, the clinician followed the child's lead and responded in ways that would encourage the produc tion of the possessive construction. In the structured conditions,

Rebecca M. Landa; Lesley B. Olswang

1988-01-01

292

Oral Health among 35- to 44YearOld Iranians  

Microsoft Academic Search

Objective: To investigate the oral health status of 35- to 44-year-old Iranians in relation to gender, place of residence and education. Subjects and Methods: In 2002, data (n = 8,301) were collected as part of a national survey using WHO criteria for sampling and clinical diagnoses across 28 provinces by 33 calibrated examiners who performed examinations under a dental light

Hossein Hessari; Miira M. Vehkalahti; Mohammad J. Eghbal; Heikki T. Murtomaa

2007-01-01

293

Recommended Immunizations for Children from 7 Through 18 Years Old  

MedlinePLUS

2013 Recommended Immunizations for Children from 7 Through 18 Years Old 7–10 YEARS 11-12 YEARS13-18 YEARS Tdap 1 ... high risk for pneumococcal disease. 6 Hepatitis A vaccination is recommended for older children with certain medical ...

294

Triadic Interaction among Newly Acquainted 2-year-olds  

Microsoft Academic Search

Are children as young as 2 years old able to interact in groups of three? The study applied the family triad model first introduced by Parke, Power, and Gottman (1979) to the case of peer interaction. In Experiment 1, the model was refined for use in studies of peer interaction and applied to an existing dataset of 16 triads of

Fumiko Ishikawa; Dale F. Hay

2006-01-01

295

Sebaceous adenitis in a 7-year-old Arabian gelding.  

PubMed

A 7-year-old Arabian gelding was presented with a 9-month history of progressive patches of nonpruritic scaling, crusting, alopecia, and leukoderma of the periocular areas and muzzle, becoming generalized over time. Sebaceous adenitis was diagnosed on histopathologic examination. Lesions resolved without treatment, coinciding with regression of a sarcoid on the neck. PMID:16808233

Osborne, Christina

2006-06-01

296

Sebaceous adenitis in a 7-year-old Arabian gelding  

PubMed Central

Abstract A 7-year-old Arabian gelding was presented with a 9-month history of progressive patches of nonpruritic scaling, crusting, alopecia, and leukoderma of the periocular areas and muzzle, becoming generalized over time. Sebaceous adenitis was diagnosed on histopathologic examination. Lesions resolved without treatment, coinciding with regression of a sarcoid on the neck.

2006-01-01

297

Repetitive Behaviours in Typically Developing 2-Year-Olds  

ERIC Educational Resources Information Center

Background: Repetitive behaviours are an essential part of the diagnosis of autism but are also commonly seen in typically developing children. The current study investigated the frequency and factor structure of repetitive behaviours in a large community sample of 2-year-olds. Methods: A new measure, the Repetitive Behaviour Questionnaire (RBQ-2)…

Leekam, Susan; Tandos, Jonathan; McConachie, Helen; Meins, Elizabeth; Parkinson, Kathryn; Wright, Charlotte; Turner, Michelle; Arnott, Bronia; Vittorini, Lucia; Le Couteur, Ann

2007-01-01

298

The Passive in 3- and 4-Year-Olds  

ERIC Educational Resources Information Center

|This paper argues that analyzing the patterns of individual subject performance in tests of comprehension of passives might give insight into how little children interpret passives: 3 and 4 year-olds seem to go through a range of passive interpretation, that varies from actual comprehension to total non-comprehension. The fact that some small…

de Barros Pereira Rubin, Maraci Coelho

2009-01-01

299

Gallbladder mucocele in a 12-year-old cocker spaniel  

PubMed Central

A 12-year-old, spayed cocker spaniel was presented for panting behavior which had increased over the past several months. A diagnosis of hyperadrenocorticism was made, and ultrasound imaging revealed the presence of a gallbladder mucocele. While often an incidental finding, gallbladder mucoceles can have consequences and require intervention. The etiology, diagnosis, and management of gallbladder mucoceles are discussed.

Norwich, Alison

2011-01-01

300

Urethral Mucosa Prolapse in an 18-Year-Old Adolescent  

PubMed Central

Urethra mucosa prolapse is a benign condition in which there is a circular protrusion of the distal urethra through the external urethra meatus. It is more commonly seen in prepubertal black girls and postmenopausal white women. It is rare in the reproductive age group. This case describes the presentation and management of an 18-year-old adolescent with urethra mucosa prolapse.

Olumide, Akadiri; Kayode Olusegun, Ajenifuja; Babatola, Bakare

2013-01-01

301

Use of Apostrophes by Six to Nine Year Old Children  

ERIC Educational Resources Information Center

This paper investigated six to nine year old children's ability to use contractive and possessive apostrophes, the effects of type and token frequency, and the effect of teaching on this ability. Apostrophes provide an interesting opportunity to examine the basis of frequency effects in rule inference, as type and token frequencies dissociate in…

Stuart, Morag; Dixon, Maureen; Masterson, Jackie

2004-01-01

302

Giant parapox infection in a two year old child.  

PubMed

We report the case of a two year old boy who developed a large tumour on his face. The lesion resembled a pyogenic granuloma clinically and histologically. Viral studies indicated a parapox infection and a bovine source was supported on epidemiological grounds. The lesion was removed by shave excision and the area healed without significant scarring. PMID:2562071

Rogers, M; Bale, P; De Silva, L M; Glasson, M J; Collins, E

1989-01-01

303

Persistent left sciatic artery eliminated need for revascularization in a 13-year-old with pseudoaneurysm of the superficial femoral artery.  

PubMed

Persistent sciatic artery (PSA) is an anatomical variation which is rare and most frequently diagnosed secondary to its clinical complications. The sciatic artery walls have a tendency to aneurysmal degeneration and may evolve to thrombosis or thromboembolism. This article reports the case of a 13-year-old male patient with left superficial femoral artery pseudoaneurysm after gunshot wound and complete PSA with in-line flow to the popliteal artery as incidental finding. The patient underwent coil embolization of the pseudoaneurysm with the sciatic artery left intact. The technical aspects are discussed and the literature on diagnosis and therapeutic approach of this anatomical variation is reviewed. PMID:23393087

Tsilimparis, Nikolaos; Khare, Amitesh; Riesenmann, Paul J; Reeves, James G

2013-02-06

304

Internet Use and Psychological Well-Being among 10-Year-Old and 11-Year-Old Children  

ERIC Educational Resources Information Center

|This paper uses data from the 2009 Kids' Life and Times Survey, involving 3657 children aged 10 or 11 years old in Northern Ireland. The survey indicated high levels of use of Internet applications, including social-networking sites and online games. Using the KIDSCREEN-27 instrument, the data indicate that the use of social-networking sites and…

Devine, Paula; Lloyd, Katrina

2012-01-01

305

Internet Use and Psychological Well-Being among 10-Year-Old and 11-Year-Old Children  

ERIC Educational Resources Information Center

This paper uses data from the 2009 Kids' Life and Times Survey, involving 3657 children aged 10 or 11 years old in Northern Ireland. The survey indicated high levels of use of Internet applications, including social-networking sites and online games. Using the KIDSCREEN-27 instrument, the data indicate that the use of social-networking sites and…

Devine, Paula; Lloyd, Katrina

2012-01-01

306

Are Story Preferences Sex-Linked for 2 and 3 Year Olds and for 4 and 5 Year Olds?  

ERIC Educational Resources Information Center

This study attempted to determine: (1) whether 2-, 3-, 4-, and 5-year-old children have sex typed story preferences; and (2) whether an attempt on the part of parents to prevent sex stereotyping would affect sex typed preferences. A review of previous research discusses measures used to determine sex linked responses and the implications of…

Ross, Martha

307

Multifocal meningioangiomatosis in a 3-year-old patient.  

PubMed

Meningioangiomatosis consists of benign hamartomatous lesions of the brain and the leptomeninges, which typically present with seizure. Management is predicated on resection and control of seizures with medication. Lesions are typically solitary. Multifocal meningioangiomatosis is extremely rare, with only 2 cases reported in adults and none in children. The authors report the first case, to their knowledge, of multifocal meningioangiomatosis in a child. This unique case highlights therapeutic challenges associated with these lesions and demonstrates that multifocality is possible in the pediatric population. This finding has implications for diagnosis and follow-up for children afflicted with these tumors. PMID:23020197

Jamil, Osama; Ramkissoon, Shakti; Folkerth, Rebecca; Smith, Edward

2012-09-28

308

Patterns of Temporal Genetic Variation in Coho Salmon: Estimates of the Effective Proportion of 2-Year-Olds in Natural and Hatchery Populations  

Microsoft Academic Search

The majority of coho salmon Oncorhynchus kisutch south of central British Columbia spawn when they are 3 years old, so gene flow among brood years occurs predominately when precocious 2-year-old males (jacks) spawn successfully. To determine how much gene flow among brood years is occurring, we evaluated temporal differences in allozyme allele frequencies in four coho salmon populations in Washington

Donald M. Van Doornik; Michael J. Ford; David J. Teel

2002-01-01

309

Cosmetic Clitoridectomy in a 33YearOld Woman  

Microsoft Academic Search

The Female Genital Mutilation Act (2003) in England allows for mental health exceptions for cosmetic surgery resulting from\\u000a perceived abnormality. Similar legislation exists in other countries. There are no reported cases of clitoridectomy for cosmetic\\u000a reasons or any discussion in the literature of mental health exceptions to the Act. This is a single case report on a 33-year-old\\u000a married, heterosexual

David Veale; Joe Daniels

310

Heart Health...Your Choice. 11-14 Year Olds.  

ERIC Educational Resources Information Center

|The purpose of this illustrated booklet is to teach 11-14 year old students that all healthy Americans, 2 years of age or older, should eat in a way that is low in saturated fat and cholesterol to help reduce the risk of heart disease. The guide is designed to promote changes in eating patterns, to show children how to switch to good eating…

National Heart, Lung, and Blood Inst. (DHHS/NIH), Bethesda, MD.

311

Dietary Habits of Welsh 12-13 Year Olds  

ERIC Educational Resources Information Center

|This study examined the dietary habits of Welsh 12-13 year olds. A cohort of 84 boys and 81 girls, age 12.9 SD 0.3 years; body mass 51.3 SD 12.6kg; and stature 1.54 SD 0.08m, completed a food frequency questionnaire and seven-day food diary. Mean daily kilocalories (kcal/d), and percentages of total fat, saturated fat, carbohydrate, and protein,…

Thomas, Non-Eleri; Cooper, Stephen-Mark; Graham, Mike; Boobier, Wyndham; Baker, Julien; Davies, Bruce

2007-01-01

312

Victimization and bullying among 8-year-old Finnish children  

Microsoft Academic Search

Objective  There are only few population-based time-trend studies on changes in prevalence of bullying and victimization among children.\\u000a The main aim of this study was to find out whether changes have occurred in prevalence rates of bullying and victimization\\u000a from 1989 to 1999 among eight-year-old children. The associations between victimization and bullying and psychiatric symptoms\\u000a and their possible differences in the

Päivi Santalahti; Andre Sourander; Minna Aromaa; Hans Helenius; Kaija Ikäheimo; Jorma Piha

2008-01-01

313

Treatment of a four-year-old victim of incest  

Microsoft Academic Search

A case study describing the use of behavior techniques in the treatment of a four—year—old sexual assault victim is presented. The target behaviors included eating, phobic behaviors, self—injurious behaviors, and comments made about the father (the perpetrator) and the paternal grandmother. The child's mother served as both data collector and therapist. The study demonstrates that child victims can experience a

Judith V. Becker; Linda J. Skinner; Gene G. Abel

1982-01-01

314

Sleeve Gastrectomy in a 10-year-old Child  

Microsoft Academic Search

Adolescents bariatric surgery (ABS) in morbid obesity (MO), with or without comorbid conditions, is and will be more and more\\u000a indicated. Restrictive operations have the advantage of no influence on absorption. Laparoscopic sleeve gastrectomy (LSG)\\u000a can be an excellent alternative. A LSG was done in a 10-year-old boy, body mass index (BMI) 42, who has Blount’s disease (tibia\\u000a vara) with

Aniceto Baltasar; Carlos Serra; Rafael Bou; Marcelo Bengochea; Luis Andreo

2008-01-01

315

A five-year-old child with renal hydatidosis.  

PubMed

Abstract. Hydatidosis is a zoonosis of worldwide distribution caused by the parasite Echinococcus granulosus. Clinical manifestations include cyst formation, most commonly in the liver (67-89%) and lungs (10-15%). Renal localizations are rare. We report a case of renal hydatidosis in a five-year-old child treated in a tertiary pediatric hospital in Argentina. After the diagnosis was made, elective surgery was performed, which led to a rapid recovery. PMID:23897992

Moscatelli, Guillermo; Moroni, Samanta; Freilij, Héctor; Salgueiro, Fabián; García Bournissen, Facundo; Altcheh, Jaime

2013-07-29

316

Eyewitness identification by 5-to 6-year-old children  

Microsoft Academic Search

Thirty-four 5-to 6-year-old children participated in a unique event in which children interacted with 4 individuals-2 for a long period of time and 2 for a brief period only. Each child was interviewed 1 to 2 days later with photographic lineups that contained the target individuals (target-present) or with lineups that did not (target-absent). When tested with target-present lineups, 5-to

Julien Gross; Harlene Hayne

1996-01-01

317

The cause of 50 million-year-old colour.  

PubMed Central

Multilayer reflectors cause structural, 'metallic' colours in a diversity of animals today, yet are unknown in extinct species. We identify a multilayer reflector, causing structural colour, in a 50-million-year-old beetle from Messel, Germany. It is proposed that the original material of this reflector has been preserved, although this is not a precondition for determining original colours from ancient multilayer reflectors. Therefore, the potential exists to reveal the original colours of other (particularly arthropod) extinct species.

Parker, Andrew R; McKenzie, David R

2003-01-01

318

Dietary Habits of Welsh 12-13 Year Olds  

ERIC Educational Resources Information Center

This study examined the dietary habits of Welsh 12-13 year olds. A cohort of 84 boys and 81 girls, age 12.9 SD 0.3 years; body mass 51.3 SD 12.6kg; and stature 1.54 SD 0.08m, completed a food frequency questionnaire and seven-day food diary. Mean daily kilocalories (kcal/d), and percentages of total fat, saturated fat, carbohydrate, and protein,…

Thomas, Non-Eleri; Cooper, Stephen-Mark; Graham, Mike; Boobier, Wyndham; Baker, Julien; Davies, Bruce

2007-01-01

319

Gender identity disorder in a five-year-old boy.  

PubMed Central

Markedly effeminate behavior in a young boy is a source of concern and confusion for parents, teachers, and the child. It also represents a therapeutic dilemma for the child psychiatrist. The case of a five-year-old boy with gender identity disorder of childhood is presented and the literature on hypotheses of etiology, treatment, and long-term follow-up is reviewed. The ethical and philosophical questions posed by such a case are discussed.

Herman, S. P.

1983-01-01

320

Classroom postures of 8–12 year old children  

Microsoft Academic Search

This study examined classroom postures of 8–12 year old school children in Flanders and related the outcomes to self-reported back or neck pain. Postural behaviours using the portable ergonomic observation (PEO) method and self-reported one-week back and neck pain were studied in 105 children from 41 different class groups. Pupils sat statically for 85% of the time, 28% of which

E. Geldhof; D. De Clercq; I. De Bourdeaudhuij; G. Cardon

2007-01-01

321

A 14-year-old girl with recumbent proteinuria  

Microsoft Academic Search

We describe a 14-year-old female who presented with persistently elevated nighttime urinary protein excretion without additional\\u000a clinical symptoms. She had no evidence of intrinsic renal disease on physical examination or laboratory studies. Ultrasound\\u000a examination of the abdomen revealed a large cyst arising from the spleen. CT scan showed compression of the left renal vein\\u000a by the splenic cyst. Removal of

M. Khurram Faizan; Laura S. Finn; Angelisa M. Paladin; Ruth A. McDonald

2002-01-01

322

Dietary habits of Welsh 12—13 year olds  

Microsoft Academic Search

This study examined the dietar y habits of Welsh 12—13 year olds. A cohor t of 84 boys and 81 girls, age 12.9 SD 0.3 years; body mass 51.3 SD 12.6kg; and stature 1.54 SD 0.08m, completed a food frequency questionnaire and seven-day food diary. Mean daily kilocalories (kcal\\/d), and percentages of total fat, saturated fat, carbohydrate, and protein, as

Non-Eleri Thomas; Stephen-Mark Cooper; Mike Graham; Wyndham Boobier; Julien Baker; Bruce Davies

2007-01-01

323

[Isolated ptosis in a 58-year-old woman].  

PubMed

A 60-year-old woman who had experienced isolated ptosis for two years was seen when it had been fixed for one year. She had a personal and familial history of stromal corneal dystrophy. The diagnosis of mitochondrial cytopathy was made on the basis of clinical, electrophysiological, biological and histological findings. Surgical repair of the ptosis allowed visual recovery. The relationship between ptosis, corneal dystrophy and mitochondrial cytopathy is discussed. PMID:16106815

Tourbah, A; Sedel, F; Miléa, D; Bellefqih, S; Lyon-Caen, O

2005-05-01

324

[A clinic analysis of 62 male patients with lupus nephritis].  

PubMed

To study the difference between male and female patients with lupus nephritis(LN), we made a retrospective analysis. The clinical characteristics of 62 male patients with LN were compared with 62 female patients with LN. The result indicated the distribution of LN onset ages was different between male and female patients with LN. The incidence of LN was higher in the male than in female patients with SLE. Male patients were often misdiagnosed or diagnosed long after the onset of the disease. Arthritis and positive rate of ANA were less commonly occurred in female patients with LN. Other clinical and pathologic features of LN were similar in male and female patients. The response to treatment and prognosis of male patients with LN was relatively poor. So male patients with LN should be paid more attention to. PMID:12903459

Li, H; Li, X; Chu, G; Liu, J; Bi, Z

2000-08-01

325

An 11-Year-Old Child with Autosomal Dominant Polycystic Kidney Disease Who Presented with Nephrolithiasis  

PubMed Central

Patients with autosomal dominant polycystic kidney disease become symptomatic and are diagnosed usually at adulthood. The rate of nephrolithiasis in these patients is 5–10 times the rate in the general population, and both anatomic and metabolic abnormalities play role in the formation of renal stones. However, nephrolithiasis is rare in childhood age group. In this paper, an 11-year-old child with autosomal dominant polycystic kidney disease presenting with nephrolithiasis is discussed.

Firinci, Fatih; Soylu, Alper; Kasap Demir, Belde; Turkmen, Mehmet; Kavukcu, Salih

2012-01-01

326

Metastatic Breast Cancer in a 54YearOld Woman: Integrative Treatment with Yttrium90 Radioembolization  

Microsoft Academic Search

In 1993, a 54-year-old woman was diagnosed with early-stage breast adenocarcinoma and treated with doxorubicin and cyclophosphamide followed by tamoxifen. Nine years later, the patient presented for integrative treatment, with liver metastases. Carcinoembryonic antigen was significantly elevated. The patient was started on a heavily fractionated, multiple-agent chemotherapy regimen; however, she underwent significant adverse effects and the treatment was suspended. She

Daniel Rubin; Charles Nutting; Bonita Jones

2004-01-01

327

Anemia secondary to valproic acid therapy in a 13-year-old boy: a case report  

PubMed Central

Introduction Valproic acid is a commonly used anti-epileptic drug. Hematological toxicities are among the occasionally observed adverse effects of this medication. Case presentation We present the case of a 13-year-old Caucasian boy who demonstrated mild anemia 12?months after the introduction of valproic acid therapy. A bone marrow biopsy revealed maturation arrest of proerythroblasts. Conclusion Prompt diagnosis and valproic acid discontinuation resulted in the patient’s recovery.

2012-01-01

328

[Human papillomavirus infection in male genitalia].  

PubMed

A prospective and transversal study in 100 patients since January to December of 1994, was done, to know the human papiloma virus infection prevalence in male genitals. The patients were studied by a clinical history, genital area colposcopic revision after acetic acid 5% application, biopsy of the lesion and histopathology study. The patients age was among 16 to 71 years old, with a media of 38.8 years old. The sexual activity beginning was from 12 to 27 years old, with an average of 18 years old. Forty one percent of the patients have had sexual relations with prostitutes, 26% have had sexually transmitted diseases, 9% of the patients referred only 1 sexual mate and 82% had human papiloma virus infection. PMID:8549928

Cano Garfias, R; Villarreal Peral, C; Juárez Azpilcueta, A

1995-10-01

329

75 FR 76636 - Anthropomorphic Test Devices; Hybrid III 6-Year-Old Child Test Dummy, Hybrid III 6-Year-Old...  

Federal Register 2010, 2011, 2012, 2013

...572 [Docket No. NHTSA-2010-0147] RIN 2127-AK34 Anthropomorphic Test Devices; Hybrid III 6-Year-Old Child Test Dummy, Hybrid III 6-Year-Old Weighted Child Test Dummy AGENCY: National Highway Traffic Safety Administration,...

2010-12-09

330

Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds  

PubMed Central

Influenza vaccination is now recommended for all ages; CDC pneumococcal polysaccharide vaccination (PPV) recommendations are comorbidity-based in nonelderly patients. We constructed a Markov model to estimate the cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds. Patients were followed for 10 years, with differing time horizons examined in sensitivity analyses. With 100% vaccine uptake, dual vaccination cost $37,700/QALY gained compared to a CDC recommendation strategy; with observed vaccine uptake, dual vaccination cost $5,300/QALY. Results were sensitive to shorter time horizons, favoring CDC recommendations. We found dual vaccination of all 50-year-olds economically reasonable. Shorter duration models may not fully account for PPV effectiveness.

Smith, Kenneth J; Lee, Bruce Y.; Nowalk, Mary Patricia; Raymund, Mahlon; Zimmerman, Richard K.

2010-01-01

331

An 81-year-old gentleman with symptomatic Bochdalek hernia.  

PubMed

An 81-year-old gentleman with congenital polycystic kidney disease presented to his primary care physician with dysphagia, gastroesophageal reflux refractory to medical management, and 11.25 kg weight loss in a 6 mo-period. A barium swallow misdiagnosed a paraesophageal hernia for a Bochdalek hernia. Herein, we highlight how a Bochdalek hernia may be disregarded in the differential diagnosis and how providers can resort to a more common diagnosis, a paraesophageal hernia, which is more frequently encountered in old age and whose radiologic appearance might mimic a Bochdalek hernia. PMID:23894690

Rajput, Mohammed Zak; Fisichella, Piero Marco

2013-07-27

332

Ballpoint pen ingestion in a 2-year-old child.  

PubMed

A 2-year-old girl ingested a ballpoint pen, which was found on chest x-ray to have lodged in the lower esophagus and stomach. The pen, which measured nearly 15 cm in length, was removed via rigid esophagoscopy without complication. To the best of our knowledge, this is the longest nonflexible foreign body ingested by a young child ever reported in the English-language literature. We describe the presentation of this case and the current guidelines for safety as enumerated in the Small Parts Regulations established by the U.S. Consumer Product Safety Commission. PMID:21792786

Rameau, Anaïs; Anand, Sumeet M; Nguyen, Lily H

2011-07-01

333

Characterization of 80-million-year-old mollusk shell proteins.  

PubMed Central

Fossil glycoproteins of the soluble organic matrix are present in an 80-million-year-old mollusk shell from the Late Cretaceous Period. Discrete molecular weight components, as determined by gel electrophoresis, are preserved. The fossil organic matrix was compared with the organic matrix of a living representative species of the same superfamily. A particular repeating amino acid sequence, found in contemporary mollusk shell proteins, was identified in the fossil glycoproteins. The ultrastructure, mineralogy, and chemistry of the inorganic components of the fossil and contemporary shells provide information on the state of preservation of the fossil. The use of fossil shell proteins to further our understanding of molecular evolution is discussed. Images

Weiner, S; Lowenstam, H A; Hood, L

1976-01-01

334

Ameloblastic fibroma in one-year-old girl  

PubMed Central

Ameloblastic fibroma (AF) is a relatively rare, slow growing benign mixed odontogenic tumor, comprising of 1.5-4.5% of all odontogenic tumors. It is usually asymptomatic except for the eventual expansion of the jaw. AFs are most common in adolescents and young adults, mostly affecting the mandible as a well-defined uni or multilocular radiolucency. The effective surgical treatment includes enucleation and curettage of the surrounding bone and removal of the affected teeth. Although recurrence of AF is rare, a long term follow up is recommended. This report describes a 1-year-old girl with AF in the mandible and discusses its clinical, radiographic and histological findings.

Munde, Anita D; Karle, Ravindra R; Kale, Ujwala B

2013-01-01

335

Ashy dermatosis in an 8-year-old Indian child.  

PubMed

Ashy dermatosis is a disorder of pigmentation, characterized by asymptomatic symmetric ashy gray-colored macules, in the first to third decade of life. It can, however, affect children sometime. But, there is a paucity of similar cases in Indian children. We present a case of ashy dermatosis in an 8-year-old Indian girl who presented to skin OPD with areas of ashy pigmentation, which were distributed symmetrically. Skin biopsy was consistent with lichenoid pattern histology. This case has been reported to highlight the rarity of ashy dermatosis in Indian children. PMID:23439983

Keisham, Chitralekha; Sarkar, Rashmi; Garg, V K; Chugh, Shikha

2013-01-01

336

[Traumatic odontoid synchodrotic slip in a 2-year old child].  

PubMed

We report a case of a two-and-a-half year-old child involved in a head-on motor vehicle accident, which is a typical mechanism of traumatic injury of the odontoid process in small children. The child was neurologically intact and the first X-ray was without signs of fractures. Two weeks later, X-ray revealed a 1 cm anterior luxation of the odontoid process. After closed reduction the child was treated conservatively with a Minerva jacket, which led to consolidation. PMID:9381569

Houshian, S; Grossmann, P

1997-09-29

337

Trisomy 14 mosaicism in a 5-year-old boy.  

PubMed

We report on a 5-year-old boy with failure to thrive, mental retardation, a broad nose, hypertelorism, slight antimongoloid slant palpebral fissures, mild ptosis, microphthalmia, short and wide neck, apparently acyanotic tetralogy of Fallot, dislocation of the left hip, generalized linear and patchy hyperpigmentation, micropenis, and undescended testes. He had mosaicism of 46,XY/47,XY, + 14 in a ratio of 3:1. Comparisons are made with the other reports of trisomy 14 mosaicism and relationship to incontinentia pigmenti. PMID:1887854

Vachvanichsanong, P; Jinorose, U; Sangnuachua, P

1991-07-01

338

Frontal Lobe Morphometry with MRI in a Normal Age Group of 6-17 Year-Olds  

PubMed Central

Background Morphometric data of the frontal lobe are important for surgical planning of lesions in the frontal lobe and its surroundings. Magnetic resonance imaging (MRI) techniques provide suitable data for this purpose. Objectives In our study, the morphometric data of mid-sagittal MRI of the frontal lobe in certain age and gender groups of children have been presented. Patients and Methods In a normal age group of 6-17-year-old participants, the length of the line passing through predetermined different points, including the frontal pole (FP), commissura anterior (AC), commissura posterior (PC), the outermost point of corpus callosum genu (AGCC), the innermost point of corpus callosum genu (IGCC), tuberculum sella (TS), AGCC and IGCC points parallel to AC-PC line and the point such line crosses at the frontal lobe surface (FCS) were measured in three age groups (6-9, 10-13 and 14-17 years) for each gender. Results The frontal lobe morphometric data were higher in males than females. Frontal lobe measurements peak at the age group of 10-13 in the male and at the age group of 6-13 in the female. In boys, the length of FP-AC increases 4.1% in the 10-13 age group compared with the 6-9-year-old group, while this increase is 2.3% in girls. Conclusion Differences in age and gender groups were determined. While the length of AGCC-IGCC increases 10.4% in adults, in children aged 6-17, the length of AC-PC is 11.5% greater than adults. These data will contribute to the preliminary assessment for developing a surgical plan in fine interventions in the frontal lobe and its surroundings in children.

Ilkay Kosar, M; Otag, Ilhan; Sabanc?ogullar?, Vedat; Atalar, Mehmet; Tetiker, Hasan; Otag, Aynur; Cimen, Mehmet

2012-01-01

339

Unexplained refractory iron-deficiency anaemia in a 41-year-old woman  

Microsoft Academic Search

The clinical and instrumental findings revealed a case of autoimmune polyendocrine syndrome (APS) type 3B+C in a 41-year-old Caucasian woman with unexplained refractory iron-deficiency anaemia secondary to autoimmune atrophic gastritis and a long-term history of two different autoimmune diseases—Hashimoto's disease and vitiligo. Indeed the occurrence in the same patient of three or more autoimmune diseases defines APS. The first classification

N. de Matthaeis; G. L. Rapaccini; L. Riccardi; D. Pugliese

2010-01-01

340

Carotid dissection causing stroke in a 13-year-old boy with mild hyperhomocysteinemia: case report.  

PubMed

The author describes a 13-year-old Thai boy who developed stroke caused by carotid dissection and found mild elevation of plasma homocysteine (tHcy). The patient improved after anticoagulation therapy and his plasma tHcy decreased after vitamin supplement. With long-term follow-up, he is having normal neurological condition. This case proposes that the pathogenesis of carotid dissection may associate with mild hyperhomocysteinemia. PMID:21675455

Lusawat, Apasri

2011-05-01

341

Primary systemic amyloidosis leading to advanced renal and cardiac involvement in a 30-year old man  

Microsoft Academic Search

The case of a 30-year-old man with primary systemic amyloidosis is reported. Three months prior to admission the patient developed fever, night sweats, dyspnea, and bilateral ankle swelling. Recurrent left-sided pleural effusion led to further investigation when massive proteinuria with free monoclonal lambda chains in the urine became evident. Abdominal subcutaneous fat aspiration and renal biopsy confirmed the diagnosis of

I. Spyridopoulos; U. Helber; W. Voelker; P. E. Huppert; H. V. Gärtner; J. G. Saal; H. M. Hoffmeister; T. Risler

1994-01-01

342

A 71-year-old woman with a pigmented nail bed, which persisted after trauma.  

PubMed

A 71-year-old woman presented in our out-patients department with pigmentation of the nail bed of her left large toe, which had persisted after a trauma two years earlier. An inconclusive biopsy showed melanoma in situ. The lesion was excised with amputation of the big toe at the IP-joint and closed primarily. The pathological diagnosis was melanoma in situ and lentigo maligna. The lesion had been radically excised. PMID:20919673

Juten, P G; Hinnen, J W

343

Fibromyxoid sarcoma in a 4-year-old boy: case report and review of the literature  

Microsoft Academic Search

The authors report on the case of a low-grade fibromyxoid sarcoma (LGFMS) with giant rosettes in a 4-year-old boy. The tumor arose in the paravertebral region and had infiltrated the vertebral canal between L2 and S1. A review of the literature indicates that this is one of the youngest patients diagnosed with a tumor of this type, and spinal involvement

G. Rando; V. Buonuomo; C. D‘Urzo; F. Vecchio; M. Caldarelli; C. Pintus

2005-01-01

344

Fibromyxoid sarcoma in a 4-year-old boy: case report and review of the literature.  

PubMed

The authors report on the case of a low-grade fibromyxoid sarcoma (LGFMS) with giant rosettes in a 4-year-old boy. The tumor arose in the paravertebral region and had infiltrated the vertebral canal between L2 and S1. A review of the literature indicates that this is one of the youngest patients diagnosed with a tumor of this type, and spinal involvement had never been reported with LGFMS. PMID:15747125

Rando, G; Buonuomo, V; D'Urzo, C; Vecchio, F; Caldarelli, M; Pintus, C

2005-03-04

345

Diaphragmatic hernia in an 8-year-old with Ehlers-Danlos syndrome  

Microsoft Academic Search

Ehlers-Danlos syndrome (EDS) includes a group of connective-tissue disorders characterized by abnormal collagen metabolism.\\u000a The diverse spectrum of this disease and its complications present a distinct challenge to the surgeon. Patients with this\\u000a hereditary disorder may have hyperelastic or fragile skin, poor wound healing, hypermobile joints, clotting abnormalities,\\u000a spontaneous pneumothoraces, recurrent hernias, bowel perforation, and vascular complications. An 8-year-old female

J. L. Iglesias; T. Renard

1998-01-01

346

Supraorbital Blowin Fracture Presenting as an Ocular Dystopia in a Nine-Year-Old Girl  

PubMed Central

A 9-year-old girl was referred to a trauma centre with severe head injury. 3D CT scan revealed depressed fracture involving the frontal bone on the right side, right parietal bone, and right superior orbital margin, right lamina papyracea. The frontal table was managed conservatively and open reduction and internal fixation was done for the supraorbital blow in to correct the ocular dystopia. The clinical course, possible mechanism, and management of the patient are discussed.

Nallamothu, Ranganadh; Kallam, Shanmukha Reddy; Gunturu, Srikanth; Singh, Sukumar; Rachalapally, Vijay Kumar

2013-01-01

347

Unpredicted spontaneous extrusion of a renal calculus in an adult male with spina bifida and paraplegia: report of a misdiagnosis. Measures to be taken to reduce urological errors in spinal cord injury patients  

Microsoft Academic Search

BACKGROUND: A delay in diagnosis or a misdiagnosis may occur in patients with spinal cord injury (SCI) or spinal bifida as typical symptoms of a clinical condition may be absent because of their neurological impairment. CASE PRESENTATION: A 29-year old male, who was born with spina bifida and hydrocephalus, became unwell and developed a swelling and large red mark in

Subramanian Vaidyanathan; Peter L Hughes; Bhakul M Soni; Gurpreet Singh; Paul Mansour; Pradipkumar Sett

2001-01-01

348

PAGETOID RETICULOSIS IN A 5 YEAR OLD BOY  

PubMed Central

We present a rare case of pagetoid reticulosis arising in a five year old white boy. He had a history of a large chronic erythematous, scaly patch on his left buttock that had shown intermittent partial response to a topical anti-fungal medication. A punch biopsy revealed dramatic epidermal hyperplasia, with parakeratosis and prominent exocytosis of single and clustered mononuclear cells (Pautrier’s microabscesses) into the epidermis. Some of these exhibited hyperchromatic nuclei with irregular contours. They stained prominently for CD3, CD4 and CD8, with a predominance of CD8+ cells. T cell receptor gene rearrangement by PCR was negative for a clonal process on a second biopsy that was sub diagnostic on routine sections. Pagetoid reticulosis is an indolent, unilesional variant of mycosis fungoides, in which the atypical T cells may express a CD4?/CD8+ phenotype. This is in contrast to primary cutaneous epidermotropic CD8+ cytotoxic T-cell lymphoma, which is often very aggressive with a poor outcome. Pagetoid reticulosis is exceedingly rare in children and adolescents. Two features predict a benign course in this 5 year old child: the unilesional clinical presentation and the CD8 predominance of the epidermal lymphocytes.

Miedler, John; Gould, Jennifer; Tamburro, Joan; Gilliam, Anita C.

2008-01-01

349

Pharmacologic cardiac resynchronization of a 1-year-old boy with severe left ventricular dysfunction.  

PubMed

Postero-septal accessory pathways (AP) are a rare cause of intraventricular dyssynchrony and severe LV dysfunction in children. Beside the common treatment with radiofrequency ablation of septal substrates we present the case of a successful pharmacologic resynchronization in a 13/12 years old male toddler with Wolff-Parkinson-White syndrome (WPW) and severe LV dysfunction (left ventricular biplane EF of 31 %) due to intraventricular dyssynchrony with septal to posterior wall motion delay (SPWMD) of 350 ms. Interventricular mechanical delay (IVMD) was 65 ms. Using propafenone, pharmacologic cardiac resynchronization could be achieved. Pharmacologic resynchronization should be considered as safe and effective alternative to catheter ablation in very young children. PMID:22484822

Paech, Christian; Flosdorff, Patrick; Gebauer, Roman Antonin

2012-04-07

350

Dermatitis and lymphadenitis resembling juvenile cellulitis in a four-year-old dog.  

PubMed

A four-year-old, entire male toy poodle was presented with a two-and-a-half-week history of ocular discharge progressing to periorbital alopecia, depigmentation, alopecia and ulceration around the muzzle. There was also a haemorrhagic discharge from the ears, pyrexia, lethargy and generalised lymphadenopathy. The clinical, cytological, bacteriological and histopathological findings were consistent with a diagnosis of dermatitis resembling juvenile cellulitis in an adult dog. Glucocorticoid therapy led to rapid resolution of the clinical signs and the dog has remained in remission for two years after cessation of treatment. PMID:15163053

Neuber, A E; van den Broek, A H M; Brownstein, D; Thoday, K L; Hill, P B

2004-05-01

351

A 32-year-old Man with Normokalemic Thyrotoxic Periodic Paralysis  

PubMed Central

Thyrotoxic Periodic Paralysis (TPP) is a rare and life threatening condition commonly occurring in young Asian males. It is characterized by acute paralytic attacks and hypokalemia in association with thyrotoxicosis. Serum potassium levels may be normal in rare cases of TPP. The diagnosis of normokalemic TPP may be overlooked and/or delayed in most cases. Here, we describe a 32-year-old Iranian man with normokalemic TPP misdiagnosed as somatization disorder with the correct diagnosis made one year after the onset of symptoms.

Valizadeh, Neda; Zarrin, Sahar

2013-01-01

352

A 32-year-old Man with Normokalemic Thyrotoxic Periodic Paralysis.  

PubMed

Thyrotoxic Periodic Paralysis (TPP) is a rare and life threatening condition commonly occurring in young Asian males. It is characterized by acute paralytic attacks and hypokalemia in association with thyrotoxicosis. Serum potassium levels may be normal in rare cases of TPP. The diagnosis of normokalemic TPP may be overlooked and/or delayed in most cases. Here, we describe a 32-year-old Iranian man with normokalemic TPP misdiagnosed as somatization disorder with the correct diagnosis made one year after the onset of symptoms. PMID:23613659

Valizadeh, Neda; Zarrin, Sahar

2013-01-01

353

Axillary Metastasis as the First Manifestation of Occult Breast Cancer in a Male Patient  

PubMed Central

Summary Background The aim of this study was to investigate the clinicopathologic features of male breast cancer. Case Report We present the clinicopathologic data of a 72-year-old male patient with occult breast cancer, who was diagnosed and underwent surgery in our hospital. The diagnosis was confirmed by histological examination, and the patient underwent modified radical mastectomy and axillary dissection. The histological examination showed no tumor foci in the resected breast tissue, but 2 of 15 dissected axillary lymph nodes were invaded by infiltrating ductal carcinoma. Immunohistochemistry staining was negative for both estrogen and progesterone receptors, but showed expression of p53 protein (+++), proliferating cell nuclear antigen (PCNA) (+++), Bcl-2 on-coprotein (+++), nm23 protein (++), multidrug resistance protein (MRP) (++), and human epidermal receptor (HER-2) oncoprotein (+++). 24 months after being diagnosed, the patient is alive without any residual or metastatic disease. Conclusions Breast cancer is very rare in men, and the occurrence of occult breast cancer is even less common. Axillary metastases can present as the first manifestation of breast cancer in a male.

Gu, Guo-Li; Wang, Shi-Lin; Wei, Xue-Ming; Ren, Li; Zou, Fu-Xian

2009-01-01

354

Community Approaches to Serving Four-Year-Old Children in Wisconsin: Lessons Learned from Wisconsin Communities.  

ERIC Educational Resources Information Center

|The Wisconsin Forces for Four-Year-Olds Project promotes a collaborative community approach to offering universal access to four-year-old kindergarten services for Wisconsin 4-year-olds. Presented in three major sections, this report offers an overview of a community approach to serving 4-year-olds, summarizes experiences in seven communities…

Rodgers-Rhyme, Anne; Wright, Arlene

355

Bilateral temporomandibular joint dislocation in a 29-year-old man: a case report  

PubMed Central

Introduction A dislocation of the temporomandibular joint represents three percent of all reported dislocated joints. The treatment entails reduction of the deformity and this can often be achieved in a ward setting. Case presentation We present the case of a 29-year-old Caucasian man with a non-traumatic bilateral anterior temporomandibular joint dislocation. Following several unsuccessful attempts, due to both inadequate patient analgesia and sedation, joint reduction had to be performed in theatre with the patient under general anesthesia. Conclusion This case highlights the importance of providing the patient with adequate analgesia and sedation when attempting the reduction of temporomandibular joint dislocations.

2010-01-01

356

A young 20-year-old woman with an atypical tuberculin reaction.  

PubMed

A 20-year-old female patient presented with fever and swelling in the neck accompanied by anorexia and weight loss. The clinical examination revealed a febrile patient with diffuse cervical lymphadenopathy. Routine investigations were negative. A 5TU (tuberculin units) tuberculin skin test (Mantoux test) was positive with an induration of 52×40 mm after 72 h with central blistering, exudation and ulceration. Aspiration cytology from the cervical lymph node revealed the presence of caseating granulomas. The patient responded completely to antitubrecular therapy. Enhanced-tuberculin reactions may occur on occasion in tuberculosis. PMID:24027250

Khan, Umar H; Koul, Parvaiz A

2013-09-11

357

Treatment of SCFE in a healthy 5-year-old child: case report and review.  

PubMed

Slipped capital femoral epiphysis is a common adolescent hip disorder and when patients present at an age younger than 10 years, it is atypical and there is often some identifiable associated metabolic or endocrinologic abnormality. We present the case of a 5-year-old boy with idiopathic bilateral slipped capital femoral epiphysis. This patient underwent staged bilateral pinning in situ using a uniquely modified screw where the distal threads were machined-off for smooth fixation across the physis. The patient had an unremarkable postoperative course and showed evidence of remodeling and patent physes at 1-year follow-up. PMID:20847702

Lazar, Meredith A; Van Gelderen, Jeffrey T; Chu, Alice

2011-07-01

358

Two-year-olds compute syntactic structure on-line.  

PubMed

Syntax allows human beings to build an infinite number of new sentences from a finite stock of words. Because toddlers typically utter only one or two words at a time, they have been thought to have no syntax. Using event-related potentials (ERPs), we demonstrated that 2-year-olds do compute syntactic structure when listening to spoken sentences. We observed an early left-lateralized brain response when an expected verb was incorrectly replaced by a noun (or vice versa). Thus, toddlers build on-line expectations as to the syntactic category of the next word in a sentence. In addition, the response topography was different for nouns and verbs, suggesting that different neural networks already underlie noun and verb processing in toddlers, as they do in adults. PMID:20121864

Bernal, Savita; Dehaene-Lambertz, Ghislaine; Millotte, Séverine; Christophe, Anne

2010-01-01

359

[Cerebral haematoma in a 12-year-old girl].  

PubMed

A 12-year-old girl with an upper respiratory infection deteriorated suddenly with a severe headache and declining level of consciousness, and was brought to the ER on suspicion of meningitis. On arrival, the girl had a Glascow Coma Scale score of 6 and a dilated pupil that was not reactive to light. A computed tomography of the cerebrum showed a large intracerebral haematoma, which was surgically removed. The bleeding was due to an AV-malformation. The girl survived with a homonym hemianopsis as the only sequela. Stroke is one of the top ten causes of death in children. This case illustrates that adequate diagnosing and treatment can save lives and reduce disabilities. PMID:22735117

Søndergaard, Mia; Grunnet, Sarah; Born, Alfred Peter

2012-06-25

360

Malocclusion in 12-year-old Sudanese children.  

PubMed

Malocclusions are generally less common among African and Arab children than Europeans. This difference may be due to racial as well as external and environmental factors. Angle CI. III malocclusion is, however, more common among African and Arab children than in Europeans, whereas the opposite is found for Angle CI. II malocclusions. Space conditions are better in African and Arab than in European populations. The aim of the study was to assess the prevalence of malocclusion in 12 year old Sudanese children using the method for epidemiological registration devised by Björk, Krebs and Solow. The majority of the children had Angle CI. I (normal and malocclusion), followed by CI. II and CI. III malocclusion. Sagittal, vertical and transversal occlusal anomalies were not common. The number of the abnormal conditions found in the survey suggests that public awareness and preventive orthodontics are important fields when the future orthodontic service in Sudan is organized. PMID:2075148

Abu Affan, A H; Wisth, P J; Boe, O E

1990-09-01

361

Pathology Case Study: A 54-Year-Old Man with a Right Cheek Mass  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 54-year-old man has a recurrent neoplasm in his right cheek. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in head and neck pathology

Nine, Jeff S.; Schubert, Eric

2007-07-29

362

Pathology Case Study: A 68-Year-Old Woman with Brain Mass in Temporal Lobe  

NSDL National Science Digital Library

This is a neuropathology case study presented by the University of Pittsburgh Department of Pathology in which a 68-year-old female has a temporal tumor with extensive edema. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in neuropathology.

Schubert, Eric

2007-12-24

363

Pathology Case Study: Brain Mass in a 62-Year-Old Woman  

NSDL National Science Digital Library

This is a neuropathology case study presented by the University of Pittsburgh Department of Pathology in which a 62-year-old female has a brain mass. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in neuropathology.

Schubert, Eric

2007-12-27

364

Pathology Case Study: Right Cerebellopontine Angle Mass in a 64-Year-Old Woman  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 64-year-old woman is complaining of dizziness and hearing loss. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in neuropathology.

Nine, Jeff S.

2007-08-04

365

Alopecia associated with strontium ranelate use in a 62-year-old woman.  

PubMed

Strontium ranelate is an effective drug that was developed for treating osteoporosis. Here, we report the case of a 62-year-old woman who developed headache and diffuse scalp hair loss 1 week after receiving strontium ranelate treatment for osteoporosis. The treatment was subsequently stopped because of the intractable headache. Nevertheless, the patient continued to lose hair for 6 weeks following treatment discontinuation. Histopathological analysis of scalp tissues revealed anagen effluvium. The patient's hair started regrowing slowly 2 months after treatment with strontium ranelate was discontinued. PMID:22525979

Lee, Y-Y; Yang, C-H; Chen, C-H; Hwang, J-S

2012-04-12

366

Successful Sleeve Lobectomy of Inflammatory Myofibroblastic Tumor in a 4-year-old Child.  

PubMed

Primary pulmonary tumors in small children have remained a challenge for pediatric surgeons. Pneumonectomy and radical lobectomy are limitedly indicated due to surgical difficulties and sequelae. Here, we present our experience with a 4-year-old patient who suffered from an inflammatory myofibroblastic tumor. A left lower sleeve lobectomy was performed, and the patient recovered significantly after surgery. At the last follow-up, the child was growing well without any sequel, which supports our hypothesis that in small children, sleeve resection is the preferred treatment for tumors on the main stem bronchus and presents an alternative to an otherwise unavoidable pneumonectomy. PMID:23445794

Pan, Weihua; Du, Lei; Wu, Yeming; Cai, Wei

2013-02-28

367

Pathology Case Study: An 80-Year-Old Female with a Neck Mass  

NSDL National Science Digital Library

This is an ear nose & throat case study presented by the University of Pittsburgh Department of Pathology in which an 80-year-old female has insular carcinoma of the thyroid (i.e. a neck mass). Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in ear, nose, and throat medicine.

Schubert, Eric

2007-12-20

368

Multiple Presacral Teratomas in an 18-year-old Girl: A Case Report  

PubMed Central

Although the sacrococcygeal area is the most common site for a teratoma in infants, it is a rare site for a teratoma in older patients. Most of the teratomas found in this area in adults are single mass, but in a few cases, multiple masses have been reported. The author reports on the case of an 18-year-old female patient with 3 presacral teratomas. The tumors were surgically removed via a transabdominal approach and were pathologically diagnosed as mature cystic teratomas. This case report indicates that an adult presacral teratoma can appear as multiple tumors, although it is very unusual.

2011-01-01

369

Multiple Presacral Teratomas in an 18-year-old Girl: A Case Report.  

PubMed

Although the sacrococcygeal area is the most common site for a teratoma in infants, it is a rare site for a teratoma in older patients. Most of the teratomas found in this area in adults are single mass, but in a few cases, multiple masses have been reported. The author reports on the case of an 18-year-old female patient with 3 presacral teratomas. The tumors were surgically removed via a transabdominal approach and were pathologically diagnosed as mature cystic teratomas. This case report indicates that an adult presacral teratoma can appear as multiple tumors, although it is very unusual. PMID:21602968

Park, Young Jin

2011-04-30

370

A 25-year-old man with 50 teeth: Astonishing but true!!  

PubMed Central

Retained primary teeth is a well-known process but multiple retained primary, permanent, and supernumerary teeth that too in an asymptomatic, non-syndromic patient is a rare possibility that has rarely been reported in literature. This case report discusses the clinical and radiographic details along with treatment options in a 21-year-old patient having a total number of 50 teeth, i.e., 16 retained primary teeth, 32 permanent teeth, and 2 supernumerary teeth without being associated with any known syndrome complex or metabolic disorder.

Bhatia, Vishwas; Jain, Nitul; Bhatia, Garima; Garg, Rakesh

2013-01-01

371

Pathology Case Study: A 73-Year-Old Jewish Female with Anemia of Unknown Etiology  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 73-year-old Jewish woman has anemia of unknown etiology and a low reticulocyte count. Visitors are given the microscopic description, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in hematopathology.

Goldblatt, Curtis

2007-12-28

372

Late diagnosis of nodular melanoma of the foot in a 74-year-old Brazilian man.  

PubMed

The incidence and mortality of malignant melanoma is increasing. Its early diagnosis can contribute to a favorable prognosis. We report a 74-year-old black man with a dark brown mole in the right plantar area, that grew slowly in the last decade. A biopsy of the lesion revealed a nodular malignant melanoma. A wide excision of the tumor was performed 18 months ago, followed by chemotherapy for nine months. At admission, the patient was debilitated, and presented with numerous nodules in the lower limb and suprapubic area. Imaging studies disclosed chest and abdominal nodules. The patient died 13 days after admission. PMID:22446655

Santos, Vitorino M; Leal, Cristina T; Vasconcellos, Martha J M

2012-02-08

373

Risk factors for speech delay of unknown origin in 3-year-old children.  

PubMed

One hundred 3-year-olds with speech delay of unknown origin and 539 same-age peers were compared with respect to 6 variables linked to speech disorders: male sex, family history of developmental communication disorder, low maternal education, low socioeconomic status (indexed by Medicaid health insurance), African American race, and prolonged otitis media. Abnormal hearing was also examined in a subset of 279 children who had at least 2 hearing evaluations between 6 and 18 months of age. Significant odds ratios were found only for low maternal education, male sex, and positive family history; a child with all 3 factors was 7.71 times as likely to have a speech delay as a child without any of these factors. PMID:12705559

Campbell, Thomas F; Dollaghan, Christine A; Rockette, Howard E; Paradise, Jack L; Feldman, Heidi M; Shriberg, Lawrence D; Sabo, Diane L; Kurs-Lasky, Marcia

374

Kõrk beyave üstü kadõnlarda osteoporoz risk faktörleri Osteoporosis risk factors in the women over 45-years old  

Microsoft Academic Search

Aim: The social and economic burden of osteoporosis is increasing worldwide, as the population ages. The clini- cal evaluation of osteoporosis in clinical practise is de- pend on the avareness of patients and health staff. The aim of this study was to determine osteoporosis risk fac- tors on the female patients over 45-year old admitted to the menopauses outpatient clinic

Gül Põnar; Tevfik Põnar; Nevin Doan; Azize Karahan; Lale Algõer; Aysel Abbasolu; Esra Kucu

375

JAMA Patient Page: Male Sexual Dysfunction  

MedlinePLUS

... sexual dysfunction can be caused by physical or psychological problems. The June 23/30, 2004, issue of JAMA includes an article about the various types of male sexual dysfunction and treatments for them. ...

376

Infant Brain Atlases from Neonates to 1- and 2-Year-Olds  

PubMed Central

Background Studies for infants are usually hindered by the insufficient image contrast, especially for neonates. Prior knowledge, in the form of atlas, can provide additional guidance for the data processing such as spatial normalization, label propagation, and tissue segmentation. Although it is highly desired, there is currently no such infant atlas which caters for all these applications. The reason may be largely due to the dramatic early brain development, image processing difficulties, and the need of a large sample size. Methodology To this end, after several years of subject recruitment and data acquisition, we have collected a unique longitudinal dataset, involving 95 normal infants (56 males and 39 females) with MRI scanned at 3 ages, i.e., neonate, 1-year-old, and 2-year-old. State-of-the-art MR image segmentation and registration techniques were employed, to construct which include the templates (grayscale average images), tissue probability maps (TPMs), and brain parcellation maps (i.e., meaningful anatomical regions of interest) for each age group. In addition, the longitudinal correspondences between age-specific atlases were also obtained. Experiments of typical infant applications validated that the proposed atlas outperformed other atlases and is hence very useful for infant-related studies. Conclusions We expect that the proposed infant 0–1–2 brain atlases would be significantly conducive to structural and functional studies of the infant brains. These atlases are publicly available in our website, http://bric.unc.edu/ideagroup/free-softwares/.

Shi, Feng; Yap, Pew-Thian; Wu, Guorong; Jia, Hongjun; Gilmore, John H.; Lin, Weili; Shen, Dinggang

2011-01-01

377

[Lymphomatoid papulosis in a 2 1/2-year-old boy].  

PubMed

Lymphomatoid papulosis (LyP) is a rare cutaneous lymphoproliferative disorder that has malignant histologic features and a benign clinical course. LyP is classified according to the WHO/EORTC classification for cutaneous lymphoma as a CD30-positive lymphoproliferative disorder. Few previous reports have detailed features of LyP in pediatric and adolescent patients, but LyP very rarely presents in early childhood. A 2 1/2-year-old boy presented with a 1-year history of recurrent papular and nodular lesions on the face and trunk. Clinical and histopathologic criteria lead to the diagnosis lymphomatoid papulosis. PMID:22037883

Amann, P M; Megahed, M

2011-11-01

378

Systemic lupus erythematosus presenting with pulmonary thromboembolism in a 15-year-old girl  

Microsoft Academic Search

Pulmonary embolism is rare in children aged less than 15 years in whom its estimated annual incidence is 0.2 cases per 100,000,\\u000a against the approximately 700 cases per 100,000 in patients aged more than 85 years. We describe the case of a 15-year-old\\u000a girl who had a history of thrombocytopenia with anti-platelet and anti-nuclear antibodies. Misdiagnosed chest pain and dyspnea\\u000a were treated

L. Dell’Era; F. Corona; A. C. Defilippi; A. Esposito; N. Principi; S. Esposito

379

Three-year-old child with middle aortic syndrome treated by endovascular stent implantation.  

PubMed

Middle aortic syndrome (MAS) is an extremely rare anomaly and represents both a diagnostic and therapeutic challenge, particularly in young children. A case of a 3.5 year-old child with MAS and arterial hypertension is reported, where owing to the patient's young age and the length of the hypoplastic aortic segment, surgical correction with end-to-end anastomosis was not feasible. Instead of palliative bypass grafting between the thoracic and abdominal aorta, successful percutaneous balloon angioplasty and stenting of the lesion was performed with the assistance of three-dimensional rotational angiography. PMID:22638999

Moszura, Tomasz; Goreczny, Sebastian; Dryzek, Pawel; Niwald, Marek

2012-05-26

380

Intraabdominal focal fat infarction in a 75-year-old woman presenting as acute abdomen.  

PubMed

Epiploic appendagitis is a rare, self-limiting inflammation of the epiploic appendices or omental appendices. It presents as abdominal pain often misdiagnosed as appendicitis, cholecystitis, or diverticulitis. Epiploic appendagitis can be treated conservatively with anti-inflammatory and pain medications. It is important to diagnose this etiology of abdominal pain in order to avoid long-term hospital stay and other medical expenses including surgery. In this case report we present a rare case of epiploic appendagitis that presents in a 75 year old female patient. PMID:22424988

Arora, Shitij; Goyal, Hemant; Aggarwal, Prachi; Duffoo, Frantz; Basavaiah, Thara; Patel, Jigar; Hossain, Afzal

2012-03-16

381

Primary pericardial mesothelioma in a 19-year-old presenting as pericarditis.  

PubMed

Primary pericardial mesothelioma is a rare clinical entity. The association between asbestos and pericardial mesothelioma has not been well established, partly due to the small number of reported patients. Treatment options are limited for this very aggressive cancer. Surgical resection in the form of pericardiectomy can be curative, but owing to the frequently late presentation, surgical intervention is usually palliative. Chemotherapy and radiotherapy have overall poor results. We present the case of a 19-year-old man who initially had symptoms of pericarditis. He died 1 year after initial presentation. PMID:23353042

Kayatta, Michael O; Dineen, Sean P; Sica, Gabriel; Puskas, John D; Pickens, Allan

2013-01-23

382

Incidentally detected unilateral pulmonary artery agenesis with pulmonary hypoplasia in a 67 year old woman  

PubMed Central

Unilateral pulmonary artery agenesis is commonly seen associated with other congenital cardiovascular defects, when it is detected early in life, but isolated absence of the pulmonary artery is a rare entity, usually detected in adulthood. The latter patients are usually asymptomatic or might present with varied non-specific manifestations such as respiratory tract infections and hemoptysis. This report describes the imaging findings of a 67 year old female with absence of the right pulmonary artery. The embryology and clinical manifestations of the condition are reviewed.

Muthusami, Prakash; Ananthakrishnan, Ramesh; Elangovan, S.

2010-01-01

383

[Fever, leg swelling, coughing, and left upper quadrant pain in a 19-year-old woman].  

PubMed

Persistent fever and unspecific general symptoms need a complete and thorough medical history and search for infection. We report on a case of brucellosis (Malta fever) with involvement of organs in a 19-year-old woman. She had previously lived on a farm in Portugal for several weeks, where she had consumed self-produced goat cheese. After a latency period of several months, unspecific general symptoms, fever, monarthritis, an increase of transaminases, and a newly diagnosed cardiac murmur became apparent. After the serologic and cultural proof of brucellosis, the patient underwent an antibiotic combination therapy. Within 20 days she was free of symptoms and could be released. PMID:23568060

Fitzner, S; Wohlfart, J; Müller, A; Stich, A; Weiss, T

2013-05-01

384

Bifocal pyomyositis in a 3-year-old child with eczema: a case report.  

PubMed

Pyomyositis is an infection of the skeletal muscles, resulting in a pus-filled abscess. Immunodeficiency of the patient is considered to play an important role in pathogenesis. We report a case of a 3-year-old child, who presented with multifocal pyomyositis in the gastrocnemius muscle, extending to the posterior muscles of the thigh. Even though there was no evidence of immunodeficiency, the presence of atopic eczema in the big toe of the affected limb could interfere with the immune system response, and therefore, could be associated with pyomyositis. The increasing incidence of pyomyositis in non-tropical areas and its severe complications requires an acute clinical awareness. PMID:21610311

Mitsionis, Grigorios I; Paschos, Nikolaos K; Manoudis, Grigorios N; Xenakis, Theodoros A

2011-01-01

385

[Epidural blood patch for postdural puncture headache in a five-year-old child].  

PubMed

A case was presented of a 5-year-old girl who suffered an accidental dural puncture during placement of an epidural catheter under general anesthesia for orthopedic surgery. She complained of headache 4 days after the operation, which was relieved on supine position but became worse on sitting position. Her symptoms failed to respond to conservative management. An epidural blood patch was performed under general anesthesia and completely resolved her symptoms. The reported incidence of epidural blood patch for post dural puncture headache following accidental dural puncture in children is low. We outline this case and the consideration for management for epidural blood patch in pediatric patients. PMID:20960901

Haruna, Junichi; Yamanaka, Hidenori; Tachibana, Kazuya; Takeuchi, Muneyuki; Tanaka, Yayoi; Matsunari, Yasunori; Nishimura, Nobuyuki; Kinouchi, Keiko

2010-10-01

386

The case of a 1-year-old girl with hereditary hyperferritinemia cataract syndrome.  

PubMed

Hereditary hyperferritinemia cataract syndrome (HHCS) is an autosomal dominant disorder characterized by high serum ferritin levels in the absence of iron overload accompanied by early onset of bilateral cataracts. The authors report the case of HHCS in a 1-year-old girl in a family of German origin. Routine blood examination revealed serum ferritin levels up to 2530 microg/L. Slit-lamp examination showed bilateral cataracts. HHCS should be considered in cases of high serum ferritin level and bilateral cataracts, which can even occur in pediatric patients. A liver biopsy and bone marrow aspiration are unnecessary diagnostic procedures in cases of HHCS and repeated phlebotomies are harmful. PMID:19382035

Rochow, Niels; Bachmaier, Natalie; Tost, Frank; Beck, James F; Bernig, Toralf

387

Vulva Fibroadenoma Associated with Lactating Adenoma in a 26-Year-Old Nigerian Female  

PubMed Central

Background. Vulva lactating adenoma is rare and may be misdiagnosed as adenocarcinoma in frozen section and aspiration cytology if breast tissue is not anticipated. Objective. To raise the awareness of lactating vulva ectopic breast lesion among clinicians and pathologists. Case Report. We present a case of vulva fibroadenoma associated with lactating adenoma in a 26-year-old Nigerian female. Conclusion. The rarity of vulva ectopic breast tissue can present a diagnostic challenge for both the clinician and the anatomical pathologist. Once excisional biopsy is done and the lesion confirmed histologically, the anxious patient can be reassured.

Anunobi, C. C.; Obiajulu, F. J. N.; Banjo, A. A. F.; Okonkwo, A. O. E.

2013-01-01

388

Intrascrotal lipoblastoma in a ten year old: case report and review of literature  

PubMed Central

Lipoblastoma is a rare benign soft tissue tumor encountered almost exclusively in infancy and early childhood. The location of tumors varies, but most occur in the extremities, trunk, head and neck. Less frequently, lipoblastomas have been reported in the mediastinum, the retroperitoneum and the inguinal region. Only 7 cases of lipoblastoma in the scrotum have been reported so far in the English literature, with none of the patients older than 8. We report an intrascrotal lipoblastoma in a 10 year-old boy. The differential diagnosis is discussed with reference to the literature.

Nakib, Ghassan; Calcaterra, Valeria; Avolio, Luigi; Guazzotti, Marinella; Goruppi, Ilaria; Viglio, Alessandra; Pelizzo, Gloria

2013-01-01

389

Intrascrotal lipoblastoma in a ten year old: case report and review of literature.  

PubMed

Lipoblastoma is a rare benign soft tissue tumor encountered almost exclusively in infancy and early childhood. The location of tumors varies, but most occur in the extremities, trunk, head and neck. Less frequently, lipoblastomas have been reported in the mediastinum, the retroperitoneum and the inguinal region. Only 7 cases of lipoblastoma in the scrotum have been reported so far in the English literature, with none of the patients older than 8. We report an intrascrotal lipoblastoma in a 10 year-old boy. The differential diagnosis is discussed with reference to the literature. PMID:23772297

Nakib, Ghassan; Calcaterra, Valeria; Avolio, Luigi; Guazzotti, Marinella; Goruppi, Ilaria; Viglio, Alessandra; Pelizzo, Gloria

2013-03-12

390

A Giant Trichobezoar Causing Rapunzel Syndrome in a 12-year-old Female  

PubMed Central

Bezoar is a tightly packed collection of undigested material that is unable to exit the stomach. Most bezoars are of indigestible organic matter such as hair-trichobezoars; or vegetable and fruit–phytobezoars; or a combination of both. Trichobezoars commonly occur in patients with psychiatric disturbances who chew and swallow their own hair. In very rare cases, the Rapunzel syndrome hair extends through the pylorus into the small bowel causing symptom and sign of partial or complete gastric outlet obstruction. A case report of trichobezoar in the stomach causing Rapunzel syndrome in a 12-year-old female is reported.

Kawoosa, Nadeem Ul Nazeer; Zargar, Babar Rashid

2011-01-01

391

Extrarenal testicular Wilms' tumor in a 3-year-old child.  

PubMed

We report an extremely rare case of extrarenal testicular Wilms' tumor in a 3-year-old boy with intrabdominal undescended left testis. The patient was admitted because of pain and vomiting, with evidence of a huge abdominal mass. At surgery a large tumor arising from the intrabdominal testis was found. Histology showed the classical triphasic Wilms' tumor elements: epithelial, mesenchymal and blastemal areas. Extrarenal Wilms' tumors account for only 3 % of all Wilms' tumors and just ~100 cases have been reported in literature. Testicular origin is anecdotic. We present histomorphological, histogenetic, clinical, diagnostic, prognostic and therapeutic features of this rare tumor. PMID:23794024

Morandi, A; Fagnani, A M; Runza, L; Farris, G; Zanini, A; Parolini, F; Bassi, G; Gentilino, V; Macchini, F; Arnoldi, R; Leva, E

2013-06-22

392

A 38-year-old hairdresser with irritant-associated vocal cord dysfunction.  

PubMed

The present case study reports the first case of a 38-year-old hairdresser with irritant-associated vocal cord dysfunction (VCD) due to alkaline persulfate, who was referred on suspicion of occupational asthma. Several tests were performed, including specific inhalation challenge and upper airway endoscopy. During the specific inhalation challenge to alkaline persulfate, the patient experienced dysphonia and a non-significant decrease in forced expiratory volume in 1 second on spirometry. Upper airway endoscopy was then performed and revealed VCD. A specific inhalation challenge test is therefore essential in cases of VCD to exclude possible concomitant occupational asthma. PMID:22236860

Herin, F; Poussel, M; Renaudin, J-M; Leininger, A; Moreau-Colson, C; Menard, O; Paris, C

2012-01-01

393

Plasma levels of insulin and liver glycogen contents in one- and two-year old Atlantic salmon ( Salmo salar L.) during the period of parr-smolt transformation  

Microsoft Academic Search

Plasma levels of insulin were measured by specific radioimmunoassay in 1-year and 2-year old Atlantic salmon (Salmo salar) parr during the period of parr-smolt transformation. The two-year old fish were of two different categories; silvering pre-smolts\\u000a and previously mature male parr. If insulin plays an important role in parr-smolt transformation and\\/or subsequent osmoregulatory\\u000a changes it was expected that the pre-smolts

Ian Mayer; Bertil Borg; Erika M. Plisetskaya

1994-01-01

394

Lymph node metastasis in gastric cardiac adenocarcinoma in male patients  

PubMed Central

AIM: To reveal the clinicopathological features and risk factors for lymph node metastases in gastric cardiac adenocarcinoma of male patients. METHODS: We retrospective reviewed a total of 146 male and female patients with gastric cardiac adenocarcinoma who had undergone curative gastrectomy with lymphadenectomy in the Department of Surgery, Xin Hua Hospital and Rui Jin Hospital of Shanghai Jiaotong University Medical School between November 2001 and May 2012. Both the surgical procedure and extent of lymph node dissection were based on the recommendations of Japanese gastric cancer treatment guidelines. Univariate and multivariate analyses of lymph node metastases and the clinicopathological features were undertaken. RESULTS: The rate of lymph node metastases in male patients with gastric cardiac adenocarcinoma was 72.1%. Univariate analysis showed an obvious correlation between lymph node metastases and tumor size, gross appearance, differentiation, pathological tumor depth, and lymphatic invasion in male patients. Multivariate logistic regression analysis revealed that tumor differentiation and pathological tumor depth were the independent risk factors for lymph node metastases in male patients. There was an obvious relationship between lymph node metastases and tumor size, gross appearance, differentiation, pathological tumor depth, lymphatic invasion at pN1 and pN2, and nerve invasion at pN3 in male patients. There were no significant differences in clinicopathological features or lymph node metastases between female and male patients. CONCLUSION: Tumor differentiation and tumor depth were risk factors for lymph node metastases in male patients with gastric cardiac adenocarcinoma and should be considered when choosing surgery.

Ren, Gang; Chen, Ying-Wei; Cai, Rong; Zhang, Wen-Jie; Wu, Xiang-Ru; Jin, Ye-Ning

2013-01-01

395

Family poverty accounts for differences in lower-extremity amputation rates of minorities 50 years old or more with diabetes.  

PubMed

Rates of leg amputations in diabetics are known to differ among racial/ethnic groups, but the relationship between family poverty and the risk of amputation has not been fully addressed. One-hundred-seven diabetic patients, all 50 or more years old and all from ZIP code tabulation area 778, underwent their first amputations at one hospital. Linear regression evaluated differences in age and atherosclerosis severity among African-American, Hispanic-American and other patients. chi2 statistics evaluated differences among African-American, Hispanic-American and other patients, with respect to sex and type of amputation. chi2 statistics evaluated differences among fractions of African- American, Hispanic-American and other patients, with respect to those residents 50 years old and older and those of poor families. Patient groups did not differ in regard to age, atherosclerosis severity, sex or type of amputation (P>0.05). The percents who were African-American, Hispanic-American, and other (33%, 21%, and 47%, respectively) differed markedly from those of persons 50 or more years old [13%, 7%, and 79%, (w=0.81, P<0.00001)] and mirrored those of poor families [37%, 19%, and 44% (w=0.08, P>0.05)]. Family poverty accounts for differences in diabetic amputation rates of African Americans, Hispanic Americans and other persons 50 or more years old. PMID:15779497

Wachtel, Mitchell S

2005-03-01

396

First preoperative functional mapping via navigated transcranial magnetic stimulation in a 3-year-old boy.  

PubMed

Preoperative functional mapping in children younger than 5 years old remains a challenge. Awake functional MRI (fMRI) is usually not an option for these patients. Except for a description of passive fMRI in sedated patients and magnetoencephalography, no other noninvasive mapping method has been reported as a preoperative diagnostic tool in children. Therefore, invasive intraoperative direct cortical stimulation remains the method of choice. To the authors' knowledge, this is the first case of a young child undergoing preoperative functional motor cortex mapping with the aid of navigated transcranial magnetic stimulation (nTMS). In this 3-year-old boy with a rolandic ganglioglioma, awake preoperative mapping was performed using nTMS. A precise location of Broca area 4 could be established. The surgical approach was planned according to the preoperative findings. Intraoperative direct cortical stimulation verified the location of the nTMS hotspots, and complete resection of the precentral tumor was achieved. Navigated TMS is a precise tool for preoperative motor cortex mapping and is feasible even in very young pediatric patients. In children for whom performing the fMRI motor paradigm is challenging, nTMS is the only available option for functional mapping. PMID:22656259

Coburger, Jan; Karhu, Jari; Bittl, Markus; Hopf, Nikolai J

2012-06-01

397

Intelligence and Visual Motor Integration in 5-Year-Old Children with 22q11-Deletion Syndrome  

ERIC Educational Resources Information Center

|The purpose of this study was to explore the relationship between intelligence and visual motor integration skills in 5-year-old children with 22q11-deletion syndrome (22q11DS) (N = 65, 43 females, 22 males; mean age 5.6 years (SD 0.2), range 5.23-5.99 years). Sufficient VMI skills seem a prerequisite for IQ testing. Since problems related to…

Duijff, Sasja; Klaassen, Petra; Beemer, Frits; Swanenburg de Veye, Henriette; Vorstman, Jacob; Sinnema, Gerben

2012-01-01

398

Obesity in 70YearOld Subjects as a Risk Factor for 15Year Coronary Heart Disease Incidence  

Microsoft Academic Search

Objective: To investigate the role of obesity in general and waist circumference (WC) and BMI in particular as risk factors for 15-year incidence of coronary heart disease (CHD) in the elderly.Research Methods and Procedures: This prospective study was based on 1597 (737 males and 860 females) 70-year-olds free from CHD and participants of three birth cohorts examined in 1971 to

Debashish K. Dey; Lauren Lissner

2003-01-01

399

Reliability and discriminative ability of a modified Wingate rowing test in 12- to 18-year-old rowers  

Microsoft Academic Search

We evaluated (1) the test–retest reliability of the Wingate test conducted on a rowing ergometer, and (2) the sensitivity of this test in determining the differences in performance attained by 12- to 18-year-old rowers. Altogether, 297 male rowers aged 12.0–18.9 years (mean ± s: 14.8 ± 1.7) completed a maximal 30-s test on a rowing ergometer, and 80 rowers representing all age groups were

Pavle Mikulic; Davor Emersic; Goran Markovic

2010-01-01

400

Perinatal characteristics among early (10-14 years old) and late (15-19 years old) pregnant adolescents  

PubMed Central

Background Pregnancy in adolescents is a worldwide health problem and has been mostly common in poor populations. It is not clear if socioeconomic or biological factors are the main determinants of perinatal adverse outcomes in pregnant adolescents. Adolescents under 15 years old may present a high growth rate which may contribute to impair fetal growth. Our aim is to compare perinatal characteristics among early (aged 10 to 14 years) and late (aged 15 to 19 years) pregnant adolescents. Methods A cross-sectional study was performed using data from Pernambuco State 2009, obtained from DATASUS/SISNAC, a Brazilian Government, open-access public health database. Maternal and neonatal outcomes were compared between early (aged 10–14 years) and late (aged 15–19 years) pregnant adolescents. Family income was compared between early and late pregnant adolescents using a sample of 412 subjects evaluated at Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) during 2011. Statistical comparisons were made using the chi-square test was used with a significant level of 0.05; bivariate and multivariate analysis were performed. This project was approved by the Institutional Ethics Review Board. Results Data from 31,209 pregnant adolescents were analyzed. 29,733 (95.2%) were aged 15 to 19 years and 1,476 (4.7%) were aged 10 to 14 years. There were significant differences with respect to marital status, education level and number of prenatal visits of mothers aged 10 to 14 years compared to 15 to 19 years. Of importance, early adolescents had a greater rate of neonates born premature and with low birth weight. Prematurity and low birth weight remained statistically significant after multivariate analysis. Conclusions Early aged adolescents may have an increased risk of prematurity and low birth weight. These findings highlight the potential role of biological factors in newborn outcomes in pregnant adolescents.

2012-01-01

401

Esophageal Adenocarcinoma in a 40-Year-Old Man With Cystic Fibrosis: Coincidence or Not?  

PubMed Central

Objective To report a case of esophageal cancer in an adult patient with cystic fibrosis (CF) and review the relationship between these 2 diseases. Case Report A 40-year-old man with CF presented with worsening epigastric pain, weight loss, and upper gastrointestinal (GI) bleeding. Endoscopy revealed innumerable masses in the distal esophagus. The workup revealed esophageal adenocarcinoma metastatic to the liver and the lungs. Discussion Abnormal mucous secretions in CF patients impair the innate GI mucosal barriers. The incidence of both gastroesophageal reflux disease and GI malignancies is higher in patients with CF. Patients with CF now survive long enough to potentially experience the consequences of long-term acid exposure, including esophagitis, Barrett esophagus, and esophageal cancer. Conclusion Our case report adds to a small but growing body of evidence that CF is a significant risk factor for GI malignancies, including esophageal adenocarcinoma. Controlled studies are needed to determine whether a causal relationship truly exists.

Holt, Edward W.; Yimam, Kidist K.; Liberman, Martin S.

2013-01-01

402

Osteopathic manipulative treatment of a 27-year-old man after anterior cruciate ligament reconstruction.  

PubMed

Increasing instability of the knee developed in a 27-year-old man who had torn his anterior cruciate ligament (ACL) approximately 10 years prior to surgical intervention. After initial conservative treatment, including use of a functional brace for activity, the patient opted for surgical reconstruction with a patellar tendon graft. One of the authors conducted three preoperative examinations to assess the condition of the patient's musculoskeletal system. These manual examinations included findings of somatic dysfunction in the lumbo-pelvic region. In addition, there was extension of muscular tension from the injured left knee and ankle into the lower thorax and ribs 6 through 9. During the postoperative rehabilitation process, examination at regular intervals included documentation of somatic dysfunction and osteopathic manipulative treatment (OMT). Following ACL reconstruction and OMT, the patient showed increasingly stable mobility in the lumbopelvic region. Furthermore, episodic new dysfunctions readily resolved with OMT. The patient returned to his regular sports activities 6 months after surgery. PMID:16790541

Gugel, Mark R; Johnston, William L

2006-06-01

403

Case Report: Aortic Dissection and Cystic Medial Degeneration in a 24YearOld Without Marfan Syndrome  

Microsoft Academic Search

The effective management of aortic dissection relies heavily on a high index of suspicion followed by timely definitive diagnosis. Young adults without a history of blunt trauma who are not at risk for atherosclerotic disease may lower this suspicion. We present a 24-year-old patient with complaints of chest pain who presented in multiple urgent care clinics and emergency departments. With

Chris Caraang; Adel El-Bialy

2004-01-01

404

Anomalous drainage of the right superior vena cava into the left atrium in a 61-year-old woman  

Microsoft Academic Search

This report describes a 61-year-old female with an anomalous drainage of the right superior vena cava into the left atrium. The patient presented progressively severe dyspnea and precordial pain on exertion, lightheadedness, easy fatiguability and a constant decline in her performance but normal cardiac and pulmonary findings. Following a suspicious lung perfusion scan, diagnosis was assessed by echocardiography and confirmed

Stephan Rosenkranz; Alexander Stäblein; Hans J Deutsch; Hans W Verhoeven; Erland Erdmann

1998-01-01

405

Perforating eyelid injury extending to the brain stem in a 17-year-old woman: a case report  

Microsoft Academic Search

INTRODUCTION: This case report describes a patient who had a perforating eyelid injury that extended to the brain stem. CASE PRESENTATION: A 17-year-old Japanese woman complained of decreased vision in her right eye, with severe ocular pain and headaches, after the metal tip of an umbrella struck her upper right eyelid accidentally. Her vision in the right eye decreased to

Eiichiro Noda; Makoto Inoue; Izumi Yoshikawa-Kobayashi; Toshiyuki Nagamoto

2010-01-01

406

An 8-year-old boy with vertebral artery dissection with cerebellar ataxia featuring suspected vertebral artery hypoplasia  

Microsoft Academic Search

We report an 8-year-old boy with left vertebral artery dissection featuring cerebellar ataxia in which congenital vertebral artery hypoplasia was suspected as a predisposing factor in the dissection. The patient suddenly suffered from vertigo and vomiting while swimming, and he was brought to our department. The initial brain Computed Tomography (CT) demonstrated no abnormalities, and his symptoms disappeared the next

Yasuhiko Kawakami; Shin-ya Koizumi; Kentaro Kuwabara; Juri Fujimura; Junji Shirai; Makoto Watanabe; Satoru Murata; Takehide Imai; Sachiyo Takeda; Ryuji Fukazawa; Masato Takase; Takehisa Fujita; Masatoshi Hida; Osamu Fujino

2009-01-01

407

23-year-old man with a superficial cortical brain tumor.  

PubMed

A 23-year-old male presented with a tonic-clonic generalized seizure. Neuroradiological examination revealed a superficial cystic mass with a mural nodule in the right fronto-parietal lobe. Histological and immunohistochemical examination were consistent with a pigmented (melanin producing) desmoplastic ganglioglioma.These tumors have been first described in childhood, one of them displaying melanin deposits. Only twenty cases of non-infantile desmoplastic gangliogliomas have been reported in the literature, none of them pigmented. According to the clinical and histomorphology (including the desmoplastic component) features, the differential diagnosis should include the ganglioglioma, the xanthoastrocytoma pleomorphic (both tumors also with pigmented forms) and the superficial desmoplastic infantile astrocytoma. PMID:22497616

Costa, Sónia; Marques, Joana; Pereira, Pedro; Firmo, Carla; Pimentel, José

2012-05-01

408

Influence of anterior tooth alignment on peer perception in 8- to 10-year-old children.  

PubMed

The purpose of this research was to investigate whether anterior dental alignment in 8- to 10-year-old children influences the first impressions of their peers, and to verify the validity of the tested method. From colour photographs of two attractive children, one male and one female, Adobe Photoshop 5.0 was used to alter the images and create three versions of each photograph: one with good anterior dental alignment (OK smile), a second with proclination of the upper incisors (P-type smile), and finally one with moderate-to-severe anterior crowding (C-type smile). The six different photographs were shown to 121 subjects with mean age of 9.2 years (65 females and 56 males). Each subject was asked to view one photograph and subsequently respond to a questionnaire, the 'Smile perception questionnaire for children between the ages of 8 and 10' (SPQ 8-10), composed of 13 questions with graded responses. The responses for each photograph were analysed using linear regression analysis to determine the questionnaires validity as a whole and to investigate five area of common interest (honesty, intelligence, personal happiness, pleasantness, and extroversion). The results demonstrated that the questionnaire was reliable both from an internal coherence standpoint and from a test-retest reliability perspective. Data regarding the five areas of interest showed that 8- to 10-year-olds viewed their peers with well-aligned teeth more favourably as far as honesty, personal happiness, and intelligence were concerned. However, there was no statistically significant difference with regard to pleasantness and extroversion in children with harmonious, as opposed to crowded or proclined anterior teeth. PMID:20663781

Verdecchia, Federica; Bee, Marco; Lombardo, Luca; Sgarbanti, Chiara; Gracco, Antonio

2010-07-27

409

Five-year-olds are willing, but 4-year-olds refuse, to trust informants who offer new and unfamiliar labels for parts of the body.  

PubMed

This study employed the selective trust paradigm to examine how children interpret novel labels when compared with labels they already know to be accurate or inaccurate within the biological domain. The participants-3-, 4-, and 5-year-olds (N=144)-were allocated to one of three conditions. In the accurate versus inaccurate condition, one informant labeled body parts correctly, whereas the other labeled them incorrectly (e.g., calling an eye an "arm"). In the accurate versus novel condition, one informant labeled body parts accurately, whereas the other provided novel labels (e.g., calling an eye a "roke"). Finally, in the inaccurate versus novel condition, one informant labeled body parts incorrectly, whereas the other offered novel labels. In subsequent test trials, the two informants provided conflicting labels for unfamiliar internal organs. In the accurate versus inaccurate condition, children sought and endorsed labels from the accurate informant. In the accurate versus novel condition, only 4- and 5-year-olds preferred the accurate informant, whereas 3-year-olds did not selectively prefer either informant. In the inaccurate versus novel condition, only 5-year-olds preferred the novel informant, whereas 3- and 4-year-olds did not demonstrate a selective preference. Results are supportive of previous studies suggesting that 3-year-olds are sensitive to inaccuracy and that 4-year-olds privilege accuracy. However, 3- and 4-year-olds appear to be unsure as to how the novel informant should be construed. In contrast, 5-year-olds appreciate that speakers offering new information are more trustworthy than those offering inaccurate information, but they are cautious in judging such informants as being "better" at providing that information. PMID:23872524

Luu, Betty; Rosnay, Marc de; Harris, Paul L

2013-07-17

410

Aneurysm of a 32-year-old aortorenal saphenous vein bypass graft.  

PubMed

We report the case of an incidentally discovered aneurysm of a previous saphenous vein bypass graft performed 32 years earlier for a renal artery aneurysm. The patient is a 52-year-old man who initially suffered from symptoms of hypertension and left-sided back pain. Saphenous vein bypass grafting was performed with aneurysm resection. Thirty-two years after surgery, the patient underwent a magnetic resonance imaging scan for back pain, hip pain, and anemia, discovering a 1.8-cm focal aneurysm at the site of the previous bypass. The patient underwent a repeat aortorenal bypass with an 8-mm flanged Dacron graft with excision of the existing aneurysmal saphenous vein graft. PMID:22951065

Bath, Jonathan; Cho, Jae-Sung

2012-08-28

411

Cytomegalovirus Colitis in a 10 Year-Old Girl after Kidney Transplantation  

PubMed Central

Background Cytomegalovirus is an important infection in kidney Transplantation. Isolation of the CMV virus or detection of its proteins or nucleic acid in any body fluid or tissue specimen is defined as “CMV infection”. Case Presentation A 10-year-old girl was admitted frequently for vomiting and colicky watery diarrhea starting one month after renal transplantation from a non-relative living donor. Cr, BUN, serum electrolytes and also liver function tests were normal. Anti CMV IgM titer was negative before and after transplantation. On colonoscopy large aphthous like lesions were detected in the colon. CMV PCR of the lesion was strongly positive (>2000 copies/ml). The patient received Ganciclovir. Conclusion Usually CMV infected patients present with renal dysfunction after renal transplantation but other organ involvements must not be ignored. We report a patient presenting only with intestinal signs and symptoms of CMV infection.

Merrikhi, Ali-Reza; Amir-Shahkarami, Seyed-Mohammad; Saneian, Hosein

2013-01-01

412

A 71-year-old man with anaphylaxis after eating grits.  

PubMed

The allergist is frequently called on to evaluate patients after episodes of anaphylaxis to determine the cause and implement preventive measures that will reduce the patient's risk from future episodes. The etiology of anaphylaxis can be the result of numerous causes that may go undiagnosed if a thorough evaluation is not performed. We present a 71-year-old man with no history of food allergy or atopy who presented to the emergency room and then our allergy clinic for evaluation after suffering anaphylaxis after a meal of grits and shrimp. The underlying diagnosis, which was subsequently determined, requires a high index of suspicion and should be included in the differential diagnosis of any patient presenting with unexplained anaphylaxis. PMID:22370536

Posthumus, Jonathon; Borish, Larry

413

Radical prostatectomy in men less than 50 years old  

Microsoft Academic Search

We studied the effect of age on tumor progression (defined as postoperative prostate specific antigen elevation) in 543 men who underwent radical prostatectomy for clinically localized prostate cancer. Patients were divided into two age groups: patients under 50 years (N = 85) and patients older than 50 years (N = 458). The mean follow-up for both groups was S.3 years.

Maureen A. Riopel; Thomas J. Polascik; Alan W. Partin; Jurgita Sauvageot; Patrick C. Walsh; Jonathan I. Epstein

1995-01-01

414

Video games use patterns and parenteral supervision in a clinical sample of Hispanic adolescents 13-17 years old.  

PubMed

Video games have become a popular entertainment among adolescents. Although some video games are educational, there are others with high content of violence and the potential for other harmful effects. Lack of appropriate supervision of video games use during adolescence, a crucial stage of development, may lead to serious behavioral consequences in some adolescents. There is also concern about time spent playing video games and the subsequent neglect of more developmentally appropriate activities, such as completing academic tasks. Self-administered questionnaires were used to assess video game use patterns and parental supervision among 55 adolescent patients 13-17 years old (mean age 14.4 years; 56.4% males) and their parents. Parental supervision /monitoring of the adolescents video games use was not consistent and gender related differences were found regarding their video game use. Close to one third (32%) of the participants reported video game playing had interfered with their academic performance. Parents who understood video games rating system were more likely to prohibit their use due to rating. These findings underscore the need for clear and consistently enforced rules and monitoring of video games use by adolescents. Parents need to be educated about the relevance of their supervision, video games content and rating system; so they will decrease time playing and exposure to potentially harmful video games. It also supports the relevance of addressing supervision, gender-based parental supervisory styles, and patterns of video games use in the evaluation and treatment of adolescents. PMID:22788074

Colón-de Martí, Luz N; Rodríguez-Figueroa, Linnette; Nazario, Lelis L; Gutiérrez, Roberto; González, Alexis

415

Anterior hippocampal volume reduction in male patients with schizophrenia  

Microsoft Academic Search

Quantitative high resolution magnetic resonance imaging (MRI) was utilized to measure anterior, posterior, and total hippocampal volumes in 27 male patients with chronic schizophrenia and 24 male controls. To optimize measurement techniques, hippocampal volumes were: (1) acquired with 1.4-mm slices; (2) excluded with the amygdala; (3) normalized for position; and (4) corrected for total intracranial volume (ICV). The results of

Mary P Pegues; Linda J Rogers; Diane Amend; Sophia Vinogradov; Raymond F Deicken

2003-01-01

416

Cystic Dysplasia of the Rete Testis Accompanying an Inguinal Hernia: A 63-Year-Old Man  

PubMed Central

Cystic dysplasia of the rete testis (CDT) is a very rare congenital benign testicular tumor that is often associated with ipsilateral genitourinary anomalies. It is usually found in the pediatric population and must be differentially diagnosed from a malignant lesion. Here we report the case of a 63-year-old man with a left inguinal hernia who visited our urologic outpatient clinic. Scrotal ultrasonography showed a left direct inguinal hernia in the inguinal area and a well-circumscribed cystic lesion containing multiple minute cysts with echogenic foci occupying almost one-third of the left testicular parenchyma. Testicular tumor markers were within the normal range and a computed tomography scan of the abdomen showed no genitourinary abnormalities. We presumed that the left testicular lesion was malignant, and the patient underwent radical orchiectomy. However, the pathologic examination revealed a CDT. Here we present this case of a 63-year-old man with an inguinal hernia accompanied by multiple cystic lesions on the left testis.

Kang, Kyung Seok; Cho, Dae Yeon; Park, Min Gu

2011-01-01

417

Cystic dysplasia of the rete testis accompanying an inguinal hernia: a 63-year-old man.  

PubMed

Cystic dysplasia of the rete testis (CDT) is a very rare congenital benign testicular tumor that is often associated with ipsilateral genitourinary anomalies. It is usually found in the pediatric population and must be differentially diagnosed from a malignant lesion. Here we report the case of a 63-year-old man with a left inguinal hernia who visited our urologic outpatient clinic. Scrotal ultrasonography showed a left direct inguinal hernia in the inguinal area and a well-circumscribed cystic lesion containing multiple minute cysts with echogenic foci occupying almost one-third of the left testicular parenchyma. Testicular tumor markers were within the normal range and a computed tomography scan of the abdomen showed no genitourinary abnormalities. We presumed that the left testicular lesion was malignant, and the patient underwent radical orchiectomy. However, the pathologic examination revealed a CDT. Here we present this case of a 63-year-old man with an inguinal hernia accompanied by multiple cystic lesions on the left testis. PMID:21860774

Kang, Kyung Seok; Cho, Dae Yeon; Park, Min Gu; Yeo, Jeong Kyun

2011-07-24

418

Chiropractic management of a 5-year-old boy with urinary and bowel incontinence  

PubMed Central

Objective The purpose of this article is to describe chiropractic management of a 5-year-old boy with urinary and bowel incontinence. Clinical Features A 5-year-old boy presented with the primary symptoms of a complete lack of bowel and bladder control with prior surgical correction for lumbar meningocele, spinal lipoma, and tethered spinal cord. Examination revealed spinal and pelvic dysfunction. Intervention and Outcome Chiropractic treatment methods included using the Activator adjusting instrument and shortwave diathermy to the lumbar spine and sacrum. A total of 5 treatments were initially provided over a period of 4 weeks. After the initial treatment period, he was able to maintain satisfactory control of his bladder and bowel, day and night, for a period of approximately 6 months. A second course of treatments was initiated approximately 6 months later because of a recurrence of bladder and bowel incontinence. Four additional treatments were provided over a period of 4 weeks. This second course of treatment reestablished satisfactory control of bladder and bowel function. Conclusion For this patient, chiropractic care was successful in establishing satisfactory bladder and bowel control.

Kamrath, Keith R.

2010-01-01

419

Increased time to pregnancy is associated with suboptimal neurological condition of 2-year-olds  

PubMed Central

Objective To evaluate whether time to pregnancy (TTP) is associated with neurological condition of 2-year-old children born to subfertile parents. Design Data collected in a prospective, assessor-blinded follow-up study were used for cross-sectional analyses. Patients Participants were the singletons of the Groningen assisted reproductive technique cohort study: all children were born to subfertile couples (n=209). The active waiting TTP of the couples obtained from fertility charts was recorded in years and months, and was converted to decimal years. Main outcome measure The presence of minor neurological dysfunction (MND), assessed with the Hempel examination. Results MND was present in 16 (7.7%) children. TTP of children with MND (median 4.1, range 1.6–13.2) was significantly longer than that of children without MND (median 2.8, range 0.1–13.3; Mann-Whitney U test p=0.014). Logistic regression analysis on the contribution of TTP to MND resulted in a crude OR of 1.27 (95% CI 1.06 to 1.54). After correction for gestational age, parental age and parental level of education, the association remained statistically significant: OR=1.30 (95% CI 1.05 to 1.61). Conclusions Increased TTP was associated with suboptimal neurological development in 2-year-old children. This suggests that subfertility and its determinants are involved in the genesis of neurodevelopmental problems.

Seggers, Jorien; Schendelaar, Pamela; Bos, Arend F; Heineman, Maas Jan; Middelburg, Karin J; Haadsma, Maaike L; Hadders-Algra, Mijna

2013-01-01

420

Sentinel lymph node biopsy in male breast cancer patients.  

PubMed

The concept of sentinel node biopsy has been validated for female breast cancer patients whereas, ALND remains the standard of care for male breast cancer patients with similar tumours. We evaluated the results of SLN biopsy in male breast cancer patients with clinically negative axillae. This study included all male breast cancer patients who underwent SLN biopsy between February 1998 and October 2003. All patients had negative axillae on clinical examination. All patients underwent pre-operative lymphoscintigraphy. SLN biopsy was performed using a combination of Patent blue V and 99mTc-radiolabelled colloidal albumin injected peritumourally. Nine patients, 26-79 years of age, were included in the study. Pre-operative lymphoscinitgraphy identified SLNs in all patients. Intraoperatively, SLNs were successfully localised in all patients. The mean number of SLNs encountered was 2.4. Five patients had a positive SLN, four a negative SLN. Five patients (one with a negative SLN, four with a positive SLN) had been elected pre-operatively to undergo ALND regardless of findings on SLN biopsy. ALND confirmed the SLN to be negative in one patient (false-negative rate: 0%) and three of the four patients with positive SLN(s) had additional positive nodes in the axilla. SLN biopsy accurately predicted axillary lymph node status in these five patients. These findings compare favourably with findings reported in the literature regarding SLN biopsy in female breast cancer patients. SLN biopsy accurately staged the axilla in male breast cancer patients and should be considered for axillary staging in male breast cancer patients with clinically negative axillae. PMID:15135473

Goyal, A; Horgan, K; Kissin, M; Yiangou, C; Sibbering, M; Lansdown, M; Newcombe, R G; Mansel, R E; Chetty, U; Ell, P; Fallowfield, L; Kissin, M

2004-06-01

421

Multiple congenital bilateral trigger digits in a 2-year-old child: case report.  

PubMed

Trigger finger is a rare condition in children. In this paper, we report on a 2-year-old boy with multiple congenital bilateral trigger digits. The patient had no history of perinatal trauma, viral or bacterial infections, or metabolic disorders. The patient was treated with physiotherapy for one year. At the one-year follow-up, the boy presented with six trigger fingers (3 on the right hand, 3 on the left hand). Neither thumb was involved. The six trigger fingers were treated surgically: first, the right-hand trigger fingers and, six months later, those of the left hand. After each operation, a 4-week brace in extension was applied to the operated hand. The symptoms were completely resolved after surgical treatment. Many authors have recommended surgical release for the treatment of trigger finger in children; empirical treatment with physiotherapy may be an option when symptoms present or appear at an older age. PMID:23667405

De Luna, V; Potenza, V; Garro, L; Farsetti, P; Caterini, R

2013-04-05

422

Multiple Congenital Bilateral Trigger Digits in a 2-Year-Old Child: Case Report  

PubMed Central

Trigger finger is a rare condition in children. In this paper, we report on a 2-year-old boy with multiple congenital bilateral trigger digits. The patient had no history of perinatal trauma, viral or bacterial infections, or metabolic disorders. The patient was treated with physiotherapy for one year. At the one-year follow-up, the boy presented with six trigger fingers (3 on the right hand, 3 on the left hand). Neither thumb was involved. The six trigger fingers were treated surgically: first, the right-hand trigger fingers and, six months later, those of the left hand. After each operation, a 4-week brace in extension was applied to the operated hand. The symptoms were completely resolved after surgical treatment. Many authors have recommended surgical release for the treatment of trigger finger in children; empirical treatment with physiotherapy may be an option when symptoms present or appear at an older age.

De Luna, V; Potenza, V; Garro, L; Farsetti, P; Caterini, R

2013-01-01

423

Rhabdomyosarcoma of spermatic cord in a 65-year-old man presenting as a groin swelling.  

PubMed

A 65-year-old man presented with a swelling in the right groin of 6 months duration. The swelling was associated with dull aching pain and the patient reported of increase in size of the swelling during lifting of heavy weights. The swelling was 6×5 cm, hard in consistency, mobile and there was no impulse of cough. Ultrasonography showed a solid mass measuring 5.3×1.5×5.2 cm arising from the spermatic cord. High-inguinal orchiectomy was performed. Histopathology revealed rhabdomyosarcoma (RMS) of the spermatic cord. Patient was advised adjuvant chemotherapy but he refused. Spermatic cord RMS is a rare tumour derived from the undifferentiated mesoderm. It is most often observed in children and adolescents. It rarely appears after the second decade of life. It usually manifests as a painless, firm to hard mass in the inguinal canal or scrotum. Radical high-inguinal orchiectomy is the treatment of choice. PMID:23814027

Prabhu, Raghunath; Natarajan, Arjun; Shenoy, Rajgopal; Vaidya, Kuldeep

2013-06-24

424

Xenophilus aerolatus Peritonitis in a six-year-old boy on maintenance eritoneal dialysis.  

PubMed

Peritonitis remains a significant complication of peritoneal dialysis (PD). Although most patients can be treated successfully with antibiotics and continue PD, the poorest outcomes are noted in patients with peritonitis secondary to gram-negative organisms, which may lead to temporary or permanent technique failure. Biofilm formation may result in. failure of appropriate antibiotic therapy to eradicate infection, necessitating catheter replacement or a switch to hemodialysis. Here, we report the first case of gram-negative peritonitis caused by Xenophilus aerolatus in a 6-year-old boy on continuous cycling PD. This case highlights the importance of close monitoring of clinical response and of collaboration with the microbiologist and microbiology lab in the identification of unusual organisms, their antimicrobial susceptibilities, and their expected characteristics. PMID:22073828

Tsampalieros, Anne K; Gooden, Marsha; Thampi, Nisha; Yau, Yvonne C W; Harvey, Elizabeth A

2011-01-01

425

Walterinnesia aegyptia envenomation in a 22-year-old female: a case report.  

PubMed

A 22-year-old woman was bitten on the third finger of her left hand by a Walterinnesia aegyptia (desert black cobra). Local signs included a marked swelling of the entire hand with pain along the left upper limb. Systemic reactions were irritability, fever, tachycardia, ventricular premature beats, nausea and high blood leukocytes count. About 15 h post-envenomation the patient had no symptoms except for a mild swelling of the hand. Despite the severe toxic venom composition of the W. aegyptia, the clinical course of our patient was relatively benign. This could be explained by the snake's behavior and the mechanism by which the venom penetrates the body. A survey of the literature revealed only a few clinical cases reported. Most of the information concerning W. aegyptia was collected from laboratory and animal studies. PMID:12657325

Lifshitz, Matitiahu; Maimon, Nimrod; Livnat, Shachar

2003-03-01

426

The natural history of Möbius syndrome in a 32-year-old man.  

PubMed

Möbius syndrome (OMIM#157900) is an extremely rare congenital entity involving bilateral or unilateral palsy of the facial nerve, usually with dysfunction of other cranial nerves (second, third, fifth, sixth, ninth, tenth and twelfth). It was estimated that Möbius syndrome occurs in 1 of 50 000 live births. The aetiology and the pathogenesis of the syndrome remain unknown. The majority of published cases were sporadic. We report on the natural history of a 32-year-old man with de novo Möbius syndrome. The diagnosis was established at the age of 9 months due to partial bilateral facial and abducent nerve palsy. Additionally, the patient demonstrated failure to thrive during infancy and childhood, many dysmorphic features, lower limb anomalies, and hypogonadism in adulthood, but his intelligence was in the normal range. The low quality of life of the patient with Möbius syndrome is emphasized. PMID:21384297

Chor??y, Monika; Le?niewicz, Ryszard; Posmyk, Renata; Halicka, Dorota; Zalewska, Anna; Wincewicz-Pietrzykowska, Anna; Chor??y, Kamila; Drozdowski, Wies?aw

427

Bilateral ovarian teratoma complicated with carcinosarcoma in a 68 year old woman: a case report  

PubMed Central

Background Composing of less than 1% of all ovarian cancers, immature teratoma is a malignancy that mainly affects the young, and they present with advanced disease. The treatment of immature teratoma is conservative primary surgery usually involving unilateral salpingo-oophorectomy followed by combination chemotherapy. Case presentation Here we present a case of a 68 year old woman with bilateral ovarian teratoma complicated with carcinosarcoma. The patient was diagnosed as FIGO stage IIIC. She underwent neoadjuvant chemotherapy and interval cytoreduction followed by optimal cytoreduction. The post operative management strategies and gynaecological follow up studies revealed no evidence of regional or distant metastasis. Conclusion Thus the choice of initial treatment should be decided in a selective fashion depending on various prognostic factors in order to increase the survival of the patients.

2011-01-01

428

[Severe dysphagia and erythrodermia in a 59-year-old man].  

PubMed

A 59-year-old man presented with a history of dysphagia and generalized myalgia and muscle weakness and a rash on the face, neck, and upper arms. Serum muscle enzymes, myoglobin, C-reactive protein, and erythrocyte sedimentation rate were elevated and antinuclear antibodies positive. Electromyographic conduction studies showed pathological changes on arm and leg muscles and magnetic resonance imaging of the oral and neck muscles. A diagnosis of dermatomyositis with severe esophageal involvement was established. Treatment with prednisolone was started and methotrexate added. Enteral feeding with a percutaneous endoscopic gastrostomy was started and a therapy with intravenous immunoglobulin (IVIG) initiated, which caused a rapid improvement of the patient's ability to swallow. This case demonstrates a patient with polymyositis/dermatomyositis who showed steroid-resistant life-threatening esophageal impairment. IVIG resulted in a dramatic improvement of symptoms. PMID:23404266

Zuber, M A; Kouba, M; Rudolph, S E; Weller, M; Hrdlicka, P

2013-03-01

429

Right ventricular myxoma in a 12-year-old child: a case report.  

PubMed

Cardiac myxoma especially of the right ventricle, is rare in children. A 12-year-old boy with right ventricle myxoma is reported. His heart murmur was found incidentally when he visited the Outpatient Department (OPD) because of upper respiratory infection symptoms. There was no exertional dyspnea, no palpitation, no syncope and no skin lesion. The echocardiogram revealed a heart tumor of about 4 x 3 cm in the right ventricle (RV) extending to the right atrium (RA). The tumor grew from the interventricular septum, resulting in an RV outlet and inlet obstruction. Magnetic resonance image (MRI) revealed a well-defined mass in the RV ventricle, with good enhancement after injecting a contrast medium. The patient received right atriotomy and total excision of the tumor with repairing of the interventricular septum base. Pathology revealed myxoma with gelatinous whitish color and central hemorrhage. At post-operative follow-up, the patient's condition was good. PMID:7850689

Tsai, T S; Chen, Y J; Hsieh, K S; Lee, P C; Chi, C S

1994-12-01

430

A 56-year-old woman with stress-induced hoarseness.  

PubMed

A 56-year-old woman was admitted to hospital due to stress-dependent hoarseness and hypertensive urgency. The patient reported peaks of blood pressure of 210/160 mm Hg in combination with hoarseness. With indirect mirror examination, the ear-nose-and throat doctor diagnosed a paralysis of the vocal cord on the left side. The authors suspected a mass affecting the vagus nerve and performed a CT-scan with iodinated contrast material of the neck and thorax. Surprisingly the CT-scan showed an aneurysm of the aortic arch with a dilatation up to 4.8 cm, a kinking of 120° and a chronic dissection in the aneurysm. During exercise or elevated blood pressure this aneurysm expanded and made a compression of the nervus laryngeus recurrens on the left side. Thus, there is an explanation for the patient's hoarseness on exertion and during hypertensive urgency. PMID:22604762

Latus, Joerg; Franke, Ulrich; Alscher, M Dominik; Braun, Niko

2012-04-23

431

Multiple Pituitary Hormone Deficiency Due toGunshot Injury in a 6-Year-Old Girl.  

PubMed

Gunshot injuries (GSI) of the cranial area have an extremely high mortality rate. Herein, we present a girl who has been living with a bullet in the posterior sellar region. A 6-year-old girl was admitted with complaints of headache, polyuria and polydypsia, which started after a GSI. At the time of admission the patient's anthropometric, physical and neurological examinations were normal. Urine output was 5.5 L/m2/24h. A water deprivation test suggested central diabetes insipidus, which responded to treatment. Evaluation of other pituitary hormones revealed central hypothyroidism and growth hormone deficiency. Pituitary hormone deficiency must be kept in mind in patients injured by a gunshot to the sellar/parasellar region. PMID:24072093

Demirbilek, Hüseyin; Ozbek, Mehmet Nuri; Baran, R?za Taner; Baran, Ahmet

2013-09-10

432

Fibromatous Uterus in a 16-Year-Old Girl: A Case Report  

PubMed Central

Although uterine leiomyomas are the most common neoplasms of the female genital tract, this is not the case when referring to women under the age of 20. Only a few cases of uterus leiomyomas have been reported in this age. Preoperative imaging evaluation is mandatory in adolescent women for the accurate detection, localization, and characterization of uterus leiomyomas. We report a case of a 16-year-old girl admitted to our hospital for pain and abdominal distention. The patient underwent multidetector CT examination of the abdomen and MR examination of the pelvis. Both imaging modalities revealed uterine enlargement and the presence of innumerable variably sized leiomyomas. Histopathologic examination following exploratory laparotomy confirmed the presence of uterus leiomyomas. The patient underwent laparoscopic myomectomy two years after the first operation, following MR examination of the pelvis.

Tsili, Athina C.; Lentoudi, Ekaterini D.; Argyropoulou, Maria I.; Dalkalitsis, Nikolaos; Batistatou, Anna; Paraskevaidis, Evangelos; Tsampoulas, Konstantine

2010-01-01

433

A 69-year-old man with excessive sweating of the right hemithorax  

PubMed Central

The pure autonomic failure is a rare entity, with only a few cases reported in the literature. The authors describe a case with compensatory excessive sweating of the right hemithorax as an initial manifestation of a pure autonomic failure, and the authors review the clinical characteristics of this disease. A 69-year-old man presented excessive sweating of the right hemithorax. Physical examination revealed orthostatic hypotension. No other neurological features were present. The autonomic study showed a low heart rate response to the Valsalva maneuver and reduced supine plasma norepinephrine levels. A pure autonomic failure was diagnosed. Treatment did not improve patient’s symptoms. Anhidrosis with asymmetrical compensatory hyperhidrosis can be the only symptom of a pure autonomic failure. The authors highlight an unusual form of presentation of a rare disease, difficult to diagnose if it is not taken into consideration.

Gil-Diaz, Aida; Conde-Martel, Alicia; Betancor-Leon, Pedro

2011-01-01

434

Osteoid osteoma of a scapula: a case report in a 34 years old woman  

PubMed Central

Osteoid osteoma is a benign bone tumor and accounts for 10% of benign tumors. Almost any bones can be involved but half of cases involving femur or tibia. Osteoid osteoma is a rare tumor of the scapula with only 18 reported cases in the literature. We presented a case of osteoid osteoma of the scapula in right shoulder in angle of coracoid and geloneid in a 34- year old woman. She had right radicular shoulder pain increased at night for 4 years. An important point about this case is that, patient was treated in long-term with miss diagnosis of cervicospinal discopathy. The key of diagnosis in this patient was paying attention to the nature of night increasing pain and performing bone scan. After the operative curettage of the tumor, the pain dramatically stopped and a few weeks of physical therapy led to full range of motion in her shoulder.

Pourfeizi, Hojjat Hossein; Sales, Jafar Ganjpour; Tabrizi, Ali

2012-01-01

435

Inoue Balloon Mitral Valvotomy in a 4-Year-Old Boy  

PubMed Central

Mitral stenosis in children often has a fulminant and rapid course. Percutaneous transvenous mitral commissurotomy is accepted as the treatment of choice for mitral stenosis not only in adults, but also in younger patients who have pliable valves. Balloon mitral valvotomy has yielded good immediate and long-term results. Herein, we report successful Inoue balloon mitral valvotomy in a 4-year-old boy who had severe, symptomatic rheumatic mitral stenosis. To our knowledge, our patient is the youngest to have undergone this procedure. In addition to the case description, we discuss the features of juvenile rheumatic mitral stenosis and several technical aspects of performing the Inoue balloon mitral valvotomy procedure in children.

Kapoor, Aditya; Moorthy, Nagaraja; Kumar, Sudeep

2012-01-01

436

A 65-year-old man with an endobronchial gossypiboma after lobectomy for abscessing pneumonia.  

PubMed

We present a case of a 65-year-old man with recurrent hemoptysis and weight loss for 6 months. Thirty-two years earlier, lobectomy of the right lower lobe had been performed for abcessing pneumonia. Due to recurrent pulmonary infections after lobectomy the patient had to retire at the age of 46. A diagnostic procedure to explain the hemoptysis was performed. A computed tomogram revealed a suspicious formation in the bronchus intermedius, and the patient was referred to our department with the suspicion of lung cancer. During bronchoscopy an endobronchial mass was detected and extracted whole with a foreign-body forceps. Textile fibers of a sponge in the histology specimen led to the final diagnosis of gossypiboma (also known as textiloma). After removal of the gossypiboma no further pulmonary infections occurred. PMID:20587107

Kreuter, Michael; Eberhardt, Ralf; Wiebel, Matthias; Schulz, Martin R; Mueller, Klaus-Michael; Herth, Felix Jf

2010-07-01

437

Primary Cardiac Pleomorphic Sarcoma Presenting as Back Pain in an 18-Year-Old Man  

PubMed Central

Soft-tissue sarcoma is the most prevalent primary malignant cardiac tumor. This sarcoma usually presents with cardiac manifestations secondary to local obstruction or arrhythmias; very rarely does it present with initial symptoms of distant metastasis. We discuss the unusual case of an 18-year-old man who emergently presented with acute-on-chronic back pain. Imaging revealed a lesion on the 12th thoracic vertebra and a large mass arising from the left atrium. The cardiac mass was resected, and immunohistochemical analysis revealed it to be a pleomorphic sarcoma that had metastasized to the spine. The patient died 2 years later of diffuse metastases. In addition to the patient's case, we discuss the nature and treatment of cardiac sarcoma.

Alsara, Osama; Rayamajhi, Supratik; Ghanem, Firas; Skaf, Elias; Abela, George S.

2013-01-01

438

Chondrosarcoma presenting as dyspnea in a 19-year-old man: a case report  

PubMed Central

Introduction Acute pulmonary embolism has varied presentations ranging from asymptomatic, incidentally discovered emboli to massive embolism, causing immediate death. Tumor embolism is a rare but unique complication of malignancies. This uncommon catastrophe of a malignant tumor in a young patient, culminating as a pulmonary embolism, is being reported for the first time. Case presentation A 19-year-old Asian man presented to the emergency service at our hospital with acute onset dyspnea. His clinical examination led to the suspicion of an acute pulmonary embolism with a lower lumbosacral radiculopathy. A magnetic resonance imaging scan of the pelvis demonstrated a chondrosarcoma arising from the right iliac wing, eroding into the common iliac vein and creeping up the inferior vena cava to lodge in the pulmonary artery, thus producing a saddle embolus. Conclusion The importance of exploring for malignancies in the event of an idiopathic pulmonary embolism is highlighted. Early detection of such malignancies can substantially affect the outcome in young patients.

2011-01-01

439

Abnormal melatonin secretion in male patients with hypogonadism  

Microsoft Academic Search

Recently we have demonstrated that melatonin secretion is increased in untreated male patients with GnRH deficiency. Testosterone\\u000a administration to these patients decreased melatonin secretion to normal levels. These data, however, did not exclude a gonadotropic\\u000a effect on melatonin secretion.\\u000a \\u000a To further elucidate whether gonadal steroids and\\/or gonadotropins modulate melatonin secretion in humans we compared untreated\\u000a young males with hypogonadotropic hypogonadism

Rafael Luboshitzky; Oded Wagner; Schahar Lavi; Paula Herer; Peretz Lavie

1996-01-01

440

Quality of spirometry in 5-to-8-year-old children.  

PubMed

INTRODUCTION: Although spirometry quality standards for children were proposed by American Thoracic Society/European Respiratory Society (ATS/ERS) in 2007, there is limited information on the percentage of children that fulfill these criteria during routine clinical testing, especially among 5-to-8-year-olds. AIMS OF THE STUDY: to report the percentage of children that met the current 2007 ATS/ERS quality criteria; explore factors potentially associated with poor quality spirometry; and ascertain the repeatability of forced expiratory volume at 0.5?sec (FEV(0.5) ), and at 1?sec (FEV(1) ), as well as forced vital capacity (FVC). METHODS: We evaluated the quality of spirometries without bronchodilator use performed at our laboratory in 2008 by 5-to-8-year-old children. FEV(1) , FEV(0.5) , FVC, back-extrapolated volume (BEV), forced expiratory time (FET), number of acceptable maneuvers, and repeatability, were computed and the percentage of tests that met the quality criteria standards was calculated. Based on our results, we propose a quality scoring system for spirometry for children that grades on a scale from A-to-F. RESULTS: Three hundred seventy-six spirometries were reviewed. Mean age was 6.7 years; (53% males); 68% fulfilled the 2005 and 2007 ATS/ERS quality standards; >90% reached a repeatability ?150 and ?100?ml, or 10%, in FVC or FEV(1) ; 87.2% reached FET ?3?sec; 88% had a BEV ?80?ml. The 90 percentile repeatability was 120?ml for FVC and FEV(1) . Quality improved with age. CONCLUSIONS: Our results support the proposal that a FET ?3?sec, a BEV ?80?ml, and repeatability in FEV(1) and FVC ?100?ml, or 10%, be taken into account as elements in quality control for spirometry in children. Pediatr Pulmonol. © 2013 Wiley Periodicals, Inc. PMID:23401425

Gochicoa-Rangel, Laura; Vargas-Domínguez, Claudia; García-Mujica, María Eugenia; Bautista-Bernal, Anaid; Salas-Escamilla, Isabel; Pérez-Padilla, Rogelio; Torre-Bouscoulet, Luis

2013-02-01

441

False aneurysm of a proper digital artery caused by repetitive microtrauma in a 16-year-old baseball player  

Microsoft Academic Search

We report a case of false aneurysm of a proper digital artery of the thumb in a 16-year-old baseball player. Resection of\\u000a the aneurysm and end-to-end anastomosis resulted in relief of the patient’s symptoms and recovery allowing a return to baseball\\u000a activity. Repetitive microtrauma, which is an atypical cause of a false aneurysm, to the ulnar aspect of the left

Wataru Miyamoto; Souichirou Yamamoto; Takahito Inoue; Yuji Uchio

2009-01-01

442

Desmoplastic small round cell tumour in a 74 year old man: an uncommon cause of ascites (case report).  

PubMed

A rare case is provided of a 74 year old man who presented with ascites of unknown etiology. CT scan of the abdomen revealed extensive omental caking, and omental biopsy cytogenetics showed findings in keeping with a diagnosis of desmoplastic small round cell tumour (DSRCT). This case is unique in that it involves a significantly older patient, negative WT1 immunohistochemical staining, and negative cytology. Despite repeated paracenteses and fluid management, the patient died in hospital secondary to renal complications. PMID:21696639

Heikkila, Andrew J; Prebtani, Ally P H

2011-06-23

443

Desmoplastic small round cell tumour in a 74 year old man: an uncommon cause of ascites (case report)  

PubMed Central

A rare case is provided of a 74 year old man who presented with ascites of unknown etiology. CT scan of the abdomen revealed extensive omental caking, and omental biopsy cytogenetics showed findings in keeping with a diagnosis of desmoplastic small round cell tumour (DSRCT). This case is unique in that it involves a significantly older patient, negative WT1 immunohistochemical staining, and negative cytology. Despite repeated paracenteses and fluid management, the patient died in hospital secondary to renal complications.

2011-01-01

444

Intra-abdominal metastasis of an intracranial germinoma via ventriculo-peritoneal shunt in a 13-year-old female.  

PubMed

A 13-year-old patient presented with massive intra-abdominal metastasis and spontaneous acute tumour lysis syndrome, 17-months after VP shunt placement for metastatic pineal germinoma treated with cranio-spinal-irradiation. Hyperhydration/rasburicase improved renal function, allowing chemotherapy with subsequent surgery. The patient remains event-free 34-months later. Risk of intra-abdominal metastasis from VP shunts is discussed. PMID:21501064

Murray, Matthew J; Metayer, Lucy E; Mallucci, Conor L; Hale, Juliet P; Nicholson, James C; Kirollos, Ramez W; Burke, G A Amos

2011-04-18

445

Assessment of Gingival Health Status among 5- and 12-Year-Old Children in Yemen: A Cross-Sectional Study  

PubMed Central

Purpose. There are limited data about the gingival health status in Yemeni children. The aim, therefore, was to assess oral hygiene status and prevalence and severity of gingivitis among Yemeni preschool and school children. Materials and Methods. A total of 5396 children were included from 5 representative Yemeni governorates: Sana'a, Hajjah, Hodeida, Hadramaut, and Taiz. Five-year olds (1292) were recruited from private kindergartens while 12-year olds (4104) were selected from public primary schools. Gingival health status was assessed using the plaque index (PI), calculus index (CAI), and gingival index (GI) on the 6 Ramfjord teeth. The latter index was used to categorize gingivitis severity at the subject level. Data were analyzed using simple hypothesis testing, as well as ordinal regression. Results. The 12-year old children had significantly much higher mean PI, CAI, and GI (P < 0.001) with 78.6% presenting with gingivitis and 47.8% with moderate gingivitis. In contrast, the figures were 27.2% and 3.1% in the younger group (P < 0.001). There were significant variations according to gender, area of residence, and governorate. Regression analysis revealed that mean PI (OR = 35), mean CAI (OR = 7.7), male gender (OR = 1.6), living in rural areas (OR = 1.4), and being from Hajjah or Sana'a were independent risk factors of gingivitis severity in the older group. For the 5-year olds, the determinants were mean PI (OR = 122), male gender (OR = 1.4), and living in Sana'a or Taiz. Conclusions. Bad oral hygiene and moderate gingivitis are highly prevalent among Yemeni preschool and school children. Geographical location appeared as important independent risk factors of gingival inflammation.

Al-Haddad, Khaled A.; Ibrahim, Yahia T.; Al-Haddad, Ahmed M.; Al-Hebshi, Nezar N.

2013-01-01

446

Interviewing Former 1- and 2Year Olds About Medical Emergencies 5 Years Later  

Microsoft Academic Search

Five years earlier, 1- and 2-year-old children who had been injured seriously enough to require hospital ER treatment had been recruited from the ER. For this study, as many of these children as could be found participated. The majority of former 1-year olds recalled nothing about these highly stressful events, whereas most former 2-year olds recalled a great deal. For

Carole Peterson; Brenda Parsons

2005-01-01

447

Employment of Minors. A Guide for 14- through 17-year-olds, Their Parents and Employers.  

ERIC Educational Resources Information Center

|This guide on the employment of minors is intended for 14- through 17-year olds, their parents, and employers. It first lists requirements for employers who hire minors. Then it lists the jobs that 14- and 15-year-old workers can do, both the types of businesses that would hire them and examples of the kinds of jobs that 14- and 15-year-olds may…

Oregon State Bureau of Labor and Industry, Portland.

448

Laboratory surveillance of influenza virus in children under 10 years old, in northern Greece, during 2004-2010  

PubMed Central

Objectives: Influenza viruses constitute one of the most common pathogens that cause acute respiratory disease in children. The aim of this study is to present the contribution of influenza viruses to influenza-like illness (ILI) in children (aged<10 years old) in Northern Greece during six influenza seasons (2004-2010). Materials and Methods: 1,242 pharyngeal swabs or/and washes from children younger than 10 years old, presented as ILI infections during the last six influenza seasons (2004-2005, 2005-2006, 2006-2007, 2007-2008, 2008-2009 and 2009-2010) were examined for influenza A and B by Real-time one step RT-PCR. Results: Influenza viruses were detected in 431 (34.7%) of the 1,242 specimens. In a total of 372 specimens were positive for influenza A and 58 for influenza B. The majority of the infected young patients were 6-10 years old (51.9%). Conclusion: Our results show that in N. Greece, influenza viruses type A and B contribute to ILI presenting infections at a rate of 34.7 % in children younger than 10 years old.

Gioula, G; Melidou, A; Exindari, M; Chatzopoulou, E; Chatzidimitriou, D; Malisiovas, N

2013-01-01

449

Malignant fibrous histiocytoma of the breast in young male patient: a case report and a review of the literature.  

PubMed

MALIGNANT FIBROUS HISTIOCYTOMA (MFH) IS A FAIRLY COMMON TUMOR IN THE DEEP SOFT TISSUES: the most frequent primary sites are the lower (49%) and upper (19%) limbs, but it has been reported even in the retroperitoneum and abdomen (16%), while localization in the breast is extremely rare (1-2). Breast cancer is rarely seen in males, accounts for approximately 1% of all breast cancer, and the breast sarcomas constitute less than 1% of breast tumors in both sexes. In the review of the literature, this is the third male and first young male with MFH. Here, we present a 37-years-old male patient who is diagnosed to have malignant fibrous histiocytoma in a variant of pleomorphic fusiform cell localized in the left breast. Following the wide local excision, the patient was given an adjuvant 50?Gy of external radiotherapy. He remained alive and well after 42 months of followup. We believe that reporting such few cases would contribute to forming treatment algorithms of rare tumors. PMID:23573437

Kocak Uzel, Esengul; Figen, Metin; Bek, Tuba Tulin; Inanc, Kubilay; Onder, Senem; Kizilkaya, Hazim Orhan

2013-03-14

450

Malignant Fibrous Histiocytoma of the Breast in Young Male Patient: A Case Report and a Review of the Literature  

PubMed Central

Malignant Fibrous Histiocytoma (MFH) is a fairly common tumor in the deep soft tissues: the most frequent primary sites are the lower (49%) and upper (19%) limbs, but it has been reported even in the retroperitoneum and abdomen (16%), while localization in the breast is extremely rare (1-2). Breast cancer is rarely seen in males, accounts for approximately 1% of all breast cancer, and the breast sarcomas constitute less than 1% of breast tumors in both sexes. In the review of the literature, this is the third male and first young male with MFH. Here, we present a 37-years-old male patient who is diagnosed to have malignant fibrous histiocytoma in a variant of pleomorphic fusiform cell localized in the left breast. Following the wide local excision, the patient was given an adjuvant 50?Gy of external radiotherapy. He remained alive and well after 42 months of followup. We believe that reporting such few cases would contribute to forming treatment algorithms of rare tumors.

Kocak Uzel, Esengul; Figen, Metin; Bek, Tuba Tulin; Inanc, Kubilay; Onder, Senem; Kizilkaya, Hazim orhan

2013-01-01

451

Invasive Ductal Breast Carcinoma Underneath a Lipoma in a Male Patient  

PubMed Central

Male breast cancer is a rare malignancy and accounts for less than one percent of all cancers in men. The authors describe the case of a 76-year-old Caucasian man with invasive ductal breast carcinoma who presented with a common lipoma. This paper reviews the current literature on epidemiology, risk factors, etiology, different types of breast cancer, clinical presentation, imaging, diagnostic workup, and treatment.

Landero, James; Glick, Bradley P.

2012-01-01

452

Synthetic Cannabinoid Overdose in a 20YearOld Male US Soldier  

Microsoft Academic Search

Popularity of synthetic cannabinoids among U.S. military service members has risen over the last several years, leading to an increase in hospitalizations and legal actions stemming from its use and possession. While synthetic cannabinoids, collectively referred to as “Spice,” are similar in structure to the active metabolites found in cannabis, significant concerns exist regarding the severity of short and long

Cristóbal S. Berry-Cabán; Juliana Ee; Victoria Ingram; Carlos E. Berry; Eugene H. Kim

2012-01-01

453

Case report: 16-Year-old male with autistic disorder with preoccupation with female feet.  

PubMed

This paper highlights clinical challenges faced when diagnosing and then treating an individual presenting to a child and adolescent psychiatry clinic because of unwelcome comments he made to female peers about their feet. Novel use of exposure therapy helped him effectively decrease his comments from 1 to 2 times per month to once every 6 months. Conceptualizing this case as the individual's failed attempts toward relationships with females instead of sexual harassment led to diminution of problematic behavior. Implications for diagnosis and treatment of individuals with Autistic Disorder displaying problematic behaviors are presented. PMID:21818675

Early, Maureen C; Erickson, Craig A; Wink, Logan K; McDougle, Christopher J; Scott, Eric L

2012-06-01

454

Case Report: 16-Year-Old Male with Autistic Disorder with Preoccupation with Female Feet  

ERIC Educational Resources Information Center

|This paper highlights clinical challenges faced when diagnosing and then treating an individual presenting to a child and adolescent psychiatry clinic because of unwelcome comments he made to female peers about their feet. Novel use of exposure therapy helped him effectively decrease his comments from 1 to 2 times per month to once every 6…

Early, Maureen C.; Erickson, Craig A.; Wink, Logan K.; McDougle, Christopher J.; Scott, Eric L.

2012-01-01

455

Case Report: 6YearOld Male with Autism and Systemic Onset Juvenile Rheumatoid Arthritis  

Microsoft Academic Search

Autism is a developmental disorder characterized by pervasive social and communication impairments and restricted range of interests and activities. Although the specific cause is unknown, proposed etiologies for autism have included autoimmune dysregulation of cellular or humoral components and maternal–fetal immunoregulation problems. Juvenile rheumatoid arthritis (JRA) constitutes several heterogeneous arthritides with onset in childhood. JRA is believed to be an

Gail Williams; Richard H. McChane; Ken Schikler

2004-01-01

456

Improvements in Behavioral Symptoms following Antibiotic Therapy in a 14-Year-Old Male with Autism.  

PubMed

This case report describes the benefits of antibiotic and antifungal therapy on behavior in a child with autism undergoing treatment for encopresis. Over the course of treatment, the child exhibited a reduction in aberrant behaviors, increased gastrointestinal function, and improved quality of life. PMID:23853732

Ramirez, P Lucas; Barnhill, Kelly; Gutierrez, Alan; Schutte, Claire; Hewitson, Laura

2013-06-19

457

Massive pulmonary embolus in a 14 year old boy  

Microsoft Academic Search

Pulmonary embolus in children is rare. A case of massive pulmonary embolus, after surgery, in a child of 14 years is described. Accident and emergency doctors should be aware that pulmonary embolus can occur in children and exercise a high index of suspicion for the diagnosis in those patients with risk factors for the condition who present acutely with typical

S D Crane; D W Beverley; M J Williams

1999-01-01

458

A Doctor Talks to 9-to-12-Year Olds.  

ERIC Educational Resources Information Center

|As a part of a series of books written by physicians for their patients, this publication explains heredity, birth, and growth patterns to pre-teen children. The chapters are written in language appropriate for children moving from childhood into their teens and deal with topics like: cells, conception, prenatal development, puberty, and changing…

Larrigo, Marion O.; Cassidy, Michael A.

459

Clinical features and polysomnographic findings in greek male patients with obstructive sleep apnea syndrome: differences regarding the age.  

PubMed

Background-Aim. Although sleep disturbance is a common complaint among patients of all ages, research suggests that older adults are particularly vulnerable. The aim of this retrospective study was to elucidate the influence of age on clinical characteristics and polysomnographic findings of obstructive sleep apnea syndrome (OSAS) between elderly and younger male patients in a Greek population. Methods. 697 male patients with OSAS were examined from December 2001 to August 2011. All subjects underwent an attended overnight polysomnography (PSG). They were divided into two groups: young and middle-aged (<65 years old) and elderly (?65 years old). We evaluated the severity of OSAS, based on apnea-hypopnea index (AHI), and the duration of apnea-hypopnea events, the duration of hypoxemia during total sleep time (TST) and during REM and NREM sleep, and the oxygen saturation in REM and in NREM sleep. Results. PSG studies showed that elderly group had significant higher duration of apnea-hypopnea events, longer hypoxemia in TST and in NREM sleep, as well as lower oxygen saturation in REM and NREM sleep than the younger group. Otherwise, significant correlation between BMI and neck circumference with AHI was observed in both groups. Conclusions. The higher percentages of hypoxemia during sleep and longer duration of apnea-hypopnea events that were observed in the elderly group might be explained by increased propensity for pharyngeal collapse and increased deposition of parapharyngeal fat, which are associated with aging. Another factor that could explain these findings might be a decreased partial arterial pressure of oxygen (PaO2) due to age-related changes in the respiratory system. PMID:23470883

George, Efremidis; Katerina, Varela; Maria, Spyropoulou; Lambros, Beroukas; Konstantina, Nikoloutsou; Dimitrios, Georgopoulos

2012-01-23

460

A 44-year-old man with bilateral eyelid swelling.  

PubMed

Swollen eyelids are commonly ascribed to allergic conjunctivitis, contact dermatitis, eczema, angioedema, or acute sinusitis. The differential diagnosis extends to thyroid eye disease; blepharitis; Sjögren's syndrome; Churg-Strauss vasculitis; Wegener's granulomatosis; Gleich syndrome; orbital and ocular lymphoid hyperplasia or adnexal lymphoma; idiopathic orbital inflammatory disease/idiopathic sclerosing orbital inflammation; rarely, orbital parasitosis; and IgG4-related diseases. The likely diagnosis proceeds from the more to the less common in patients without a history of allergy or infection. Both ocular lymphoid hyperplasia and ocular adnexal lymphoma must be considered in the differential diagnosis of persistent disease, and neither of these entities can be recognized or differentiated from one another clinically or radiologically. Early diagnosis is essential because therapy may consist of frequent follow-up and/or active intervention. Outcomes in patients treated early and appropriately are often favorable. PMID:22525399

Ricketti, Anthony J; Cleri, Dennis J; Moser, Robert L; Bilyk, Jurij R; Vernaleo, John R; Unkle, David W

461

A 42-year-old woman with breast cancer.  

PubMed

This premenopausal women has a T1c, N1 (two nodes positive) ER-positive, PR weakly positive, HER2 FISH-positive, grade 3 invasive ductal carcinoma. She has been treated with lumpectomy and axillary node dissection. The recommendation of the panel is for her to join one of the randomized trials studying the role of trastuzumab in node-positive breast cancers. Off protocol, we would recommend adjuvant chemotherapy with doxorubicin/cyclophosphamide followed by docetaxel, although numerous options are available. Chemotherapy would be followed by radiation therapy and hormonal treatment. At this point, we recommend tamoxifen, with consideration to adding goserelin (Zoladex) if the patient does not remain amenorrheic. The patient chose to enter the Intergroup trastuzumab trial. PMID:12800791

Crawford, E David

2003-05-01