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1

[78 years old male patient with fever and recurrent meningeal involvement].  

PubMed

78-year-old man who entered twice at an interval of 8 months because of fever and recurrent meningeal involvement and remaining asymptomatic between episodes. Complementary examinations were consistent with meningoencephalitis with systemic inflammatory parameters significantly altered and adrenal mass, suggestive of myelolipoma in the first-admission and adrenal lymphoma in the second. Torpid course in the second and last entry, confirming the diagnosis. PMID:24054027

Ortiz, G; Francia, E

2013-11-01

2

Male Patients Above Age 60 have as Good Outcomes as Male Patients 50–59 Years Old at 1Year Follow-up After Bariatric Surgery  

Microsoft Academic Search

Background  It is estimated that 25% of Americans older than 60 years are obese. Male gender and advanced age are indicators of increased\\u000a risk for bariatric surgery. Good results have been shown in patients older than 50, but nearly all published studies include\\u000a a large majority of females, and few include patients >60 years old. In this study, we examined the results of

Daniel Wool; Nina Bellatorre; Sherry Wren; Dan Eisenberg

2009-01-01

3

Low-tech rehabilitation and management of a 64 year old male patient with acute idiopathic onset of costochondritis  

PubMed Central

Objective This study was conducted to discuss the treatment and management of a patient presenting with acute idiopathic costochondritis. Case 64 year old male patient presenting with acute anterior chest pain of one week duration. Treatment High-velocity low-amplitude thrust manipulation was used to the zygapophyseal joints of the thoracic spine, costotransverse, and costochondral joints involved. Acupuncture, ischemic compression, cross fibre friction massage techniques, and cryotherapy were utilized on the local area of pain. Specific exercise prescription (low tech rehabilitation) was also utilized. Improvement of pain reported on the Visual Analog Scale was noted with a complete resolution of the condition at the conclusion of treatment. No recurrences were reported on an eleven month follow up of the patient. Conclusion Conservative management, including manipulation and exercise prescription, may be beneficial in the treatment of benign costochondritis. PMID:19066696

Hudes, Karen

2008-01-01

4

Case 1/2013: 69-year-old male patient with sudden back and lower right limb pain and shock.  

PubMed

The patient, MSM, a 69-year-old man, sought medical care due to left dorsal and right lower limb pain. The chest x-ray showed mediastinal enlargement. He was undergoing examination when he lost consciousness and went into shock. Subcutaneous emphysema was observed in the left hemithorax, as well as abolition of breath sounds at auscultation. Tracheal intubation was performed with draining of blood-tinged fluid from the left hemithorax. Echocardiography showed left ventricle with 44/29 mm; septum, 12 mm; posterior wall, 13 mm; mild aortic root dilation, dissection of the lamina and periaortic hematoma. The valves and pericardium were normal. The patient was transferred to Instituto do Coraçao - InCor. Physical examination (21 Oct 2004: 10:45) showed that the patient was sedated with tracheal intubation, pale, heart rate at 90 bpm, blood pressure 130 x 80 mmHg, bloody drainage in the chest tube. Electrocardiogram - frequency 90 bpm, sinus rhythm, low voltage in the frontal plane and decreased voltage in left leads (Fig. 1). Computed tomography showed bilateral subcutaneous emphysema, thoracic aorta with inaccurate borders in its descending portion (from the subclavian artery to the middle portion), collapsed left lung and extensive collection of hematic characteristics in same hemithorax and middle and posterior mediastinum. Small right pneumothorax; small right pleural effusion with underlying parenchymal alterations. The analysis of the heart was impaired by the presence of hemothorax. While undergoing computed tomography, the patient showed no pulse, mydriasis, with asystole unresponsive to resuscitation and died (21 Oct 2011; 15:00 h). PMID:23503833

Espirito Santo, Carlos Vinícius Abreu do; Franco, Rafael Alves; Benvenuti, Luiz Alberto

2013-02-01

5

One?year?old male with accelerated growth and development  

PubMed Central

A 1?year?old male child with isosexual central (gonadotropin?dependent) precocious puberty caused by hypothalamic hamartoma is reported. Details of the diagnosis based solely on neuromaging characteristics, and satisfactory results of medical treatment with gonadotropin releasing hormone agonist analogues, are highlighted. PMID:17916866

Kashyap, Ajit Singh; Anand, Kuldip Parkash; Kashyap, Surekha; Arora, Sumeet

2007-01-01

6

[Adenocarcinoma of the stomach and neuroendocrine carcinoma of the colon in a 45-year-old male patient suffering from common variable immunodeficiency (CVID) and ulcerative colitis].  

PubMed

Common variable immunodeficiency (CVID) is the most common primary antibody deficient syndrome in adults. Among the broad spectrum of clinical manifestations are recurrent infections, allergies, autoimmune, tumour, pulmonary, liver and gastrointestinal diseases. Here we report the case of a 45-year-old male patient, who has been suffering from ulcerative colitis - likewise recognised as a CVID-associated disease - for many years. He was admitted to our clinic with a rapid progressive reduction of his general condition and a loss of weight. Diagnostic work-up revealed adenocarcinoma of the stomach as well as an undifferentiated neuroendocrine carinoma of the colorectum at the rectosigmoidal junction. Curative resection of the distal stomach and proctolcolectomy were performed. To date, the pathogenesis of the association of many diseases with CVID is still ambiguous. Yet, there is no doubt about the significantly higher incidence of e.g., inflammatory bowel disease or gastric cancer in patients with CVID. Our case highlights that in patients with CVID and obscure deterioration of their general health condition a careful search for especially malignant complications is mandatory although to date there are no precise recommendations for screening. PMID:23225557

Gemeinhardt, M; Türck, J; Piper, B; Helmberger, T; Nerlich, A; Schepp, W

2012-12-01

7

63-Year-Old Male with Gastric Outlet Obstruction  

PubMed Central

We describe a case of a 63-year-old male with complicated Bouveret's syndrome, both in its presentation and in its management. Bouveret's syndrome is a rare cause of gastric outlet obstruction resulting from mechanical obstruction from gallstones at the pyloroduodenal segment. As Bouveret's syndrome can be a diagnostic and therapeutic challenge for clinicians, we aim to identify clinical and radiologic pearls that can lower the threshold for the diagnosis of Bouveret's syndrome. PMID:25298900

Rudersdorf, Patrick; Smith, Brian R.; Lall, Chandana

2014-01-01

8

Pathology Case Study: Bladder Mass in a 73-Year-Old Male  

NSDL National Science Digital Library

This case study, from the University of Pittsburgh School of Medicine's Department of Pathology, presents information about a 73-year-old male patient. According to the patient's history, he has a "history of invasive papillary transitional cell carcinoma with excessive muscular invasion and angiolymphatic invasion." Both gross and microscopic images of the prostate, bladder, pelvic lymph nodes, and the right and left pelvic ureter are provided in this case. Using these images and the provided patient history, students can test their knowledge of pathology and compare their diagnostic findings with the official findings in the "Final Diagnosis" section.

Hakam, Ardeshir

2007-07-26

9

[Recurrent canaliculitis in a 22-year-old patient].  

PubMed

A 22-year-old patient presented with persistent epiphora over a period of about 7 months. The clinical examination revealed a canalicular swelling in both lacrimal ducts, which postoperatively transpired to be an exophytic tumor. The histopathology result of the excised tumor showed an epithelial lesion, a partially inverted papilloma without malignancy. For tumors arising from lachrimal ducts the first-line therapy is complete tumor resection. PMID:22016192

Atili, A; Holke, K; Karimdadian, D; Schittkowski, M P

2011-12-01

10

Pathology Case Study: Renal Tumor in a 44-Year-Old Male  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 44-year-old male has hypernephroma, left renal tumor. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in renal pathology.

Richert, Charles A.

2007-12-19

11

Pathology Case Study: Hematuria and Azotemia in a 60-Year-Old Male with Aortic Aneurysms  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 60-year-old male has an abdominal aortic aneurysm & liver and kidney masses. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in transplant pathology.

Richert, Charles A.

2007-12-21

12

[Informed consent to the insertion of a PEG tube in a 53-year-old male patient with highly advanced dementia].  

PubMed

In patients with advanced dementia and dysphagia, regular fluid- and food intake together with oral medication can be guaranteed by insertion of a PEG tube. Consent to a treatment in a patient without legal capacity requires nomination of a legal substitute by an Austrian court. The following case report describes the problems associated with this particular situation exposing additional psychosocial stress to closest relatives and to the palliative care team in charge for the patient. This case report describes the legal options together with the finally chosen path of medical treatment which in clinical praxis may not always match. PMID:24158417

Roden, Christian

2014-05-01

13

Primary seminoma in the middle mediastinum: case report in a 69-year-old male.  

PubMed

Primary mediastinal seminoma is an uncommon tumor usually located in the anterior mediastinum. The majority of cases occur in young males. We report here an extremely rare case of a 69-year-old male with primary seminoma in the middle mediastinum. The patient had no complaints, but an abnormal shadow was seen in a routine chest X-ray. We performed a tumorectomy in the middle mediastinum, a thymectomy and an orchidectomy and added postoperative chemotherapy. It seems that the tumor was not associated with the thymus, so we believe the tumor did not stem from the embryonic thymus. Our case demonstrated that mediastinal seminoma does not always occur in the anterior mediastinum of young males. Although this case is rare, seminoma should be included among the possible diagnoses of a middle mediastinal mass. PMID:9544831

Kitami, A; Suzuki, T; Suzuki, S; Hori, G

1998-02-01

14

Pathology Case Study: 15 Year Old Male With a Left Testicular Mass  

NSDL National Science Digital Library

This genitourinary pathology case study, provided by the University of Pittsburgh Department of Pathology, is an excellent resource for students and instructors in the health science fields. A 15-year-old male with a left testicular mass is the focus of this case. The patientâÂÂs history, gross description, and microscopic description of test results are provided to aid readers in understanding the patientâÂÂs diagnosis. The official final diagnosis is accompanied by a discussion of the contributing doctorâÂÂs findings and a list of references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose patientâÂÂs conditions.

Bastacky, Sheldon; Ionescu, Diana; Molina, J. T.

2009-02-11

15

Multiple aseptic splenic abscesses in a 15 year old patient  

PubMed Central

Background Splenic abscesses in children are rare. In recent years aseptic abscesses have been recognized as a new disease entity, especially in adults. Case presentation We present a rare case of a 15 year old girl with aseptic abscesses, in whom antibiotic therapy comprising metronidazole and meropenem was partly beneficial in improving the patient’s clinical condition and inflammatory parameters. Eventually corticosteroid therapy led to complete and long lasting resolution of symptoms. Further diagnostic work-up revealed autoimmune thyroiditis, but no signs of inflammatory bowel disease. Conclusion Aseptic splenic abscesses should always prompt clinicians to initiate further diagnostics to determine a potential underlying condition and a regular follow-up. Anaerobic bacteria may play a role in the pathogenesis of the disease and besides corticosteroid treatment antibiotics covering anaerobes may be beneficial. PMID:24502393

2014-01-01

16

Myxoid liposarcoma in a 91-year-old patient  

PubMed Central

Background Myxoid liposarcoma is a mesenchymal malignancy most commonly presenting in young adults. This tumor is known for its characteristic chromosomal rearrangement at the DDIT3 locus. Results We report a case of myxoid liposarcoma in a 91-year-old, the oldest known patient with this disease-entity. FISH analysis of the DDIT3 and FUS loci demonstrate the pathognomonic chromosomal alteration in the setting of predominantly round cell histology on biopsy, confirmed by RT-PCR. Conclusion Myxoid liposarcoma affects mostly young adults but can be seen in the elderly population. Molecular and cytogenetic assays are helpful auxiliaries to histology in the setting of unusual histology and clinical presentation. PMID:24252207

2013-01-01

17

Radiology case of the month: progressive slurring of speech and difficulty reading in a 62-year-old male.  

PubMed

A 62-year-old male with controlled hypertension, coronary artery disease, and borderline diabetes presented to the emergency room after experiencing a gradual one-month progression of slurring of speech and difficulty reading. The patient maintained his vital signs throughout his ambulance ride to the hospital and was clinically stable at time of arrival to the emergency department. PMID:25075510

Stark, Chris; Gupta, Jagan D; Austin, Tracy; Palacios, Enrique; Neitzschman, Harold

2014-01-01

18

Influenza Vaccine-Induced CNS Demyelination in a 50-Year-Old Male  

PubMed Central

Patient: Male, 50 Final Diagnosis: Acute post-vaccination CNS demyelinating disorder Symptoms: Blurred vision • hemiparesis • hemiplegia • hypertonia • itching • paresthesia Medication: — Clinical Procedure: MRI Specialty: Neurology Objective: Rare disease Background: There are several categories of primary inflammatory demyelinating disorders, which comprise clinically similar neurologic sequelae. Of interest, clinically isolated syndrome (CIS) and acute disseminated encephalomyelitis (ADEM) are 2 demyelinating conditions of the central nervous system (CNS), whose clinical similarity pose a significant challenge to definitive diagnosis. Yet, both remain important clinical considerations in patients with neurologic signs and symptoms in the context of recent vaccination. Case Report: We report a case of a 50-year-old Caucasian male with a course of progressive, focal, neurologic deficits within 24 h after receiving the influenza vaccine. Subsequent work-up revealed the possibility of an acute central nervous system (CNS) demyelinating episode secondary to the influenza vaccine, best described as either CIS or ADEM. Conclusions: Case reports of CNS demyelination following vaccinations have been previously noted, most often occurring in the context of recent influenza vaccination. This report serves to document a case of CNS demyelination occurring 24 h after influenza vaccination in a middle-aged patient, and will describe some salient features regarding the differential diagnosis of CIS and ADEM, as well as their potential management. PMID:25175754

Sacheli, Aaron; Bauer, Raymond

2014-01-01

19

A 17 year old male with a testicular fibrothecoma: a case report  

PubMed Central

We herein report the case of a right-sided testicular fibrothecoma in a 17 year old male and review the pertinent literature relatable to this rare, benign lesion. Virtual slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7738283021019280. PMID:24044431

2013-01-01

20

Avascular necrosis of the hip in a 41-year-old male: a case study.  

PubMed

This case deals with the avascular necrosis or osteonecrosis of the femoral head in a 41-year-old male presenting to a chiropractor's office. In addition to the clinical picture, diagnostic imaging should be performed to confirm the presence and extent of hip avascular necrosis. Referral to an orthopedic specialist is key and treatment is mainly surgical. PMID:17549225

Karim, Rahim; Goel, Kambiz D

2004-06-01

21

Speed and agility of 12- and 14-year-old elite male basketball players.  

PubMed

The aims of this study were (a) to identify and compare the speed and agility of 12- and 14-year-old elite male basketball players and (b) to investigate relations between speed and agility for both age groups of basketball players, to help coaches to improve their work. Sixty-four players aged 12 (M = 11.98 years, SD = 0.311) and 54 players aged 14 (M = 14.092 years, SD = 0.275) were tested. Three agility tests: agility t-test, zigzag agility drill, and agility run 4 × 15 m and 3 speed tests: 20-m run, 30-m run, and 50-m run were applied. Fourteen-year-old players achieved significantly better results in all speed and agility tests compared with 12-year-old players. The correlation coefficient (r = 0.81, p = 0.001) showed that 12-year-old players have the same ability in the 30- and 50-m runs. The other correlation coefficient (r = 0.59, p = 0.001) indicated that 20- and 30-m runs had inherently different qualities. The correlation coefficients between agility tests were <0.71, and therefore, each test in this group represents a specific task. In 14-year-old players, the correlation coefficients between the speed test results were <0.71. In contrast, the correlation coefficients between the agility tests were >0.71, which means that all the 3 tests represent the same quality. During the speed training of 12-year-old players, it is advisable to focus on shorter running distances, up to 30 m. During the agility training of the same players, it is useful to apply exercises with various complexities. In speed training of the 14-year-old players, the 30- and 50-m runs should be applied, and agility training should include more specific basketball movements and activities. PMID:22067243

Jakovljevic, Sasa T; Karalejic, Milivoje S; Pajic, Zoran B; Macura, Marija M; Erculj, Frane F

2012-09-01

22

A 26-Year-Old Male with Mesothelioma Due to Asbestos Exposure  

PubMed Central

Mesothelioma is a malignancy with poor prognosis, with an average 5-year survival rate being less than 9%. This type of cancer is almost exclusively caused by exposure to asbestos. A long exposure can cause mesothelioma and so can short ones, as each exposure is cumulative. We report a case of a 26-year-old male who was exposed to asbestos during his primary school years from the age of 6 to 12. Although the tumor mainly affects older men who in their youth were occupationally exposed to asbestos, malignant mesothelioma can also occur in young adults. A medical history was carefully taken and asbestos exposure was immediately mentioned by the patient. We conducted biopsy on the right supraclavicular lymph node. The patient was not a candidate for surgery, and chemotherapy treatment was initiated. While patient's chemotherapy is still ongoing, no other similar cases of students or teachers have been traced up to date from his school. The school building was demolished in January 2009. PMID:21776278

Zarogoulidis, P.; Orfanidis, M.; Constadinidis, T. C.; Eleutheriadou, E.; Kontakiotis, T.; Kerenidi, T.; Sakkas, L.; Courcoutsakis, N.; Zarogoulidis, K.

2011-01-01

23

Blue Thursday? Homicide and suicide among urban 15-24-year-old black male Americans.  

PubMed Central

A comparative analysis was made of day of the week variations in homicide and suicide deaths among 15-24-year-old white males, black males, white females, and black females in the 22 counties with the most black persons in the United States. Thirty-seven percent of black Americans and 14 percent of white Americans lived in these densely populated counties. The authors expected a weekend excess of homicide and a Monday excess of suicide. They found a pronounced excess of homicides on weekends, especially among white males. A slight excess of suicide was observed on Monday, but other slight excesses of suicide were also found. Young black males exhibited an unexpected excess of homicides and suicides on Thursday. On Thursdays the black male-white male ratio for homicide was 1.43 and for suicide, 1.26. Possible explanations for the young black males' blue Thursday phenomenon are offered. PMID:1594735

Greenberg, M; Schneider, D

1992-01-01

24

Pathology Case Study: Osteolytic Lesion of the Tibia in a 12-Year-Old Male  

NSDL National Science Digital Library

In this case study from the Department of Pathology at the University of Pittsburgh School of Medicine, a 12-year-old male is presented with "an osteolytic lesion of the proximal left tibia." Gross and microscopic images of the bone are provided, and the diagnosis is relayed in the "Final Diagnosis" section. A discussion of the diagnosis, including the pathogenesis and morphology of the disease, is included in the final section.

Nine, Jeff S.

2007-07-25

25

18F-FDG PET/CT in a 16-year-old patient with hydranencephaly.  

PubMed

A 16-year-old male patient with a past medical history of congenital brain malformation presented for surveillance F-FDG PET/CT scan of left parotid acinic cell adenocarcinoma. F-FDG PET/CT revealed absence of gray matter activity in the bilateral cerebral hemispheres most consistent with hydranencephaly. Hydranencephaly is a rare congenital condition characterized by absent cerebral hemispheres replaced by cerebrospinal fluid-filled sacs. The etiology is hypothesized to be secondary to intrauterine bilateral internal carotid artery compromise. Most affected individuals die in utero or within weeks of birth; however, there are rare reported cases of prolonged survival as in our patient. PMID:24395017

Short, Ryan G; Kardan, Arash

2014-10-01

26

[Case report about a 35 year old patient with cystic fibrosis and metastatic pancreatic cancer].  

PubMed

Cystic fibrosis is the most common lethal genetic disease in Caucasian population. End-stage lung disease is the most frequent cause of death, however since therapeutic options have improved the life expectancy of patients with cystic fibrosis, increased incidences of gastrointestinal tumors including pancreatic carcinoma have been reported in several cohort studies from the USA and Europe. We report about a 35-year-old male patient who died from cystic fibrosis with a pancreatic carcinoma, which was histologically confirmed by autopsy. Additionally a low grade appendiceal mucinous neoplasm (LAMN) was diagnosed. PMID:24420800

Meier, F; Oltmanns, A; Brandmaier, P; Wittekind, C

2014-01-01

27

A new sarcomatoid variant of multiple myeloma in a 20-year-old male.  

PubMed

We present a 20-year-old man with a rare variant of multiple myeloma with peculiar spindle cell morphology and sarcomatoid growth. The diagnosis of multiple myeloma was substantiated by clinical examinations. The patient was treated with several therapeutic trials including autologous stem cell support. Unfortunately, he developed a disseminated aspergillosis of the lungs and died of fatal lung bleeding. We recommended that "sarcomatous" multiple myeloma be considered in cases of "unclassifiable" sarcomatous tumors of the bone marrow. PMID:14513288

Gauer, I C; Hagen, V; Merz, H

2004-04-01

28

Right Cerebellar Hemisphere Agenesis in a 19YearOld Patient Presenting Behavioural and Thought Disorders: A Case Report  

Microsoft Academic Search

The origins of schizophrenia remain unclear, in spite of approaches based on neurobiological models. Links be- tween these models and semiological aspects are sometimes not obvious because of clinical concomitances. We report here a case of right cerebellar hemisphere agenesis in a 19-year-old male patient presenting behavioural and thought disorders. This patient, who was adopted at the age of 2

Pierre Celestin Nguimfack Mbodie; Alain Drux; Didier Robin

2002-01-01

29

Pathology Case Study: Maxillary Cyst in a 36-Year-Old Male  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 36-year-old man has a maxillary cyst. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in head and neck pathology.

Schubert, Eric

2007-08-07

30

Pathology Case Study: Gastric Mass in a 70-Year-Old Male with Weight Loss  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 70-year-old man has a stomach ache, decreased appetite, and weight loss. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in gastrointestinal pathology

Richert, Charles A.; Schubert, Eric

2007-08-03

31

Pathology Case Study:A 52-Year-Old Male with "Cholelithiasis"  

NSDL National Science Digital Library

This is a gastrointestinal pathology case study presented by the University of Pittsburgh Department of Pathology in which a 52-year-old female has âÂÂcholelithiasis,â intermittant jaundice, recent pancreatitis and gallbladder polyps. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in gastrointestinal pathology.

Schubert, Eric

2007-12-26

32

Surgical Treatment of a Mixed Pineocytoma\\/Pineoblastoma in a 72YearOld Patient  

Microsoft Academic Search

Summary.\\u000a Summary.  \\u000a ?\\u000a \\u000a \\u000a \\u000a \\u000a Background:   Although pineal parenchymal tumours are very rare in elderly patients, we recently successfully treated a 72-year-old male\\u000a patient. Interestingly, the histology of his pineal parenchymal tumour was mixed pineocytoma\\/pineoblastoma, which is reported\\u000a to be extremely rare in aged patients. We present his clinical manifestations, follow-up MRI, surgical treatment, pathological\\u000a findings, and review the literature.\\u000a \\u000a ?\\u000a \\u000a \\u000a \\u000a \\u000a Clinical

R. Saito; R. Shirane; T. Oku; M. Watanabe; T. Kumabe; C.-C. Su; H. Higuchi

2002-01-01

33

Dissociative fugue symptoms in a 28-year-old male Nigerian medical student: a case report  

PubMed Central

Introduction Dissociative fugue is a psychiatric disorder characterized by amnesia coupled with sudden unexpected travel away from the individual’s usual surroundings and denial of all memory of his or her whereabouts during the period of wandering. Dissociative fugue is a rare disorder that is infrequently reported. Before now, no case of it had been reported in a medical student. Case presentation This article focuses on the report of a case of dissociative fugue symptoms in a 28-year-old male Nigerian medical student. Conclusion The observation in this case report brings to the fore that dissociative fugue is often related to stressful life events and can comorbid with a depressive disorder. PMID:23724873

2013-01-01

34

Eosinophilic granulomatous gastroenterocolitis and hepatitis in a 1-year-old male Siberian Husky.  

PubMed

A case of eosinophilic granulomatous gastroenterocolitis and hepatitis in a 1-year-old male Siberian Husky is described. The dog presented with a history of diarrhea, weakness, lethargy, and anorexia of several months' duration. Hematologic and biochemical examinations, abdominal ultrasonography, computer tomography, and exploratory laparotomy were performed. Histopathologic examination of full-thickness biopsies from the gastrointestinal tract and liver revealed the presence of eosinophilic granulomatous lesions in the submucosa and tunica muscularis of stomach, jejunum, ileum, colon, and liver. Infectious agents were not detected by light microscopic and electron microscopic examination or by immunohistochemistry. On the basis of the findings, it is concluded that the disease in this dog represents an unusual manifestation of chronic idiopathic inflammatory bowel disease. PMID:17099165

Brellou, G D; Kleinschmidt, S; Meneses, F; Nolte, I; Hewicker-Trautwein, M

2006-11-01

35

Pathology Case Study: 21 Year Old Male With Back Pain and Wobbly Gait  

NSDL National Science Digital Library

This neuropathology case study, provided by the University of Pittsburgh Department of Pathology, is an excellent learning tool for students and instructors in the health science fields. In this case, a 21-year-old man presents with a three-week history of thoracic myelopathy, decreased sensation, and a wobbly gait. Visitors are shown MRI images of the patientâÂÂs spine, along with microscopic images and a gross description of the condition. The official diagnosis found in the âÂÂFinal Diagnosisâ section is accompanied by a discussion of the contributing doctorâÂÂs findings and a list of references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose patientâÂÂs conditions

Krisky, David; Molina, J. T.; Wiley, Clayton

2009-02-16

36

Symptomatic Solitary Osteochondroma of the Subaxial Cervical Spine in a 52-Year-Old Patient  

PubMed Central

Osteochondromas are the most common benign tumors of the bone. They mostly arise from the appendicular skeleton and present clinically in the second or third decade of life. Ostechondromas arising from the subaxial cervical spine and presenting after the 5th decade of life are extremely rare. We report a 52-year-old male patient who presented with numbness and subjective weakness of left upper and lower limbs and neck pain, and had lobulated bony hard fixed swelling in the right lower cervical paraspinal region. Radiological images revealed a bony swelling arising from C4 and C5 lamina with a cartilaginous cap and intraspinal extension. Excision biopsy with stabilisation of the spine was performed. Histopathalogical examination of the specimen confirmed the diagnosis of osteochondroma. We conclude surgical excision of such rare tumors, including the cartilaginous cap as well as the intraspinal component can reliably produce a good clinical outcome. PMID:24596611

Amritanand, Rohit; Krishnan, Venkatesh; David, Kenny Samuel

2014-01-01

37

Symptomatic solitary osteochondroma of the subaxial cervical spine in a 52-year-old patient.  

PubMed

Osteochondromas are the most common benign tumors of the bone. They mostly arise from the appendicular skeleton and present clinically in the second or third decade of life. Ostechondromas arising from the subaxial cervical spine and presenting after the 5th decade of life are extremely rare. We report a 52-year-old male patient who presented with numbness and subjective weakness of left upper and lower limbs and neck pain, and had lobulated bony hard fixed swelling in the right lower cervical paraspinal region. Radiological images revealed a bony swelling arising from C4 and C5 lamina with a cartilaginous cap and intraspinal extension. Excision biopsy with stabilisation of the spine was performed. Histopathalogical examination of the specimen confirmed the diagnosis of osteochondroma. We conclude surgical excision of such rare tumors, including the cartilaginous cap as well as the intraspinal component can reliably produce a good clinical outcome. PMID:24596611

Sekharappa, Vijay; Amritanand, Rohit; Krishnan, Venkatesh; David, Kenny Samuel

2014-02-01

38

Successful Mechanical Thrombectomy in a 2-Year-Old Male Through a 4-French Guide Catheter  

PubMed Central

A 2-year-old boy with hypoplastic left heart syndrome that required multiple cardiovascular surgeries and a heterozygous prothrombin G20210A mutation with resulting thrombophilia maintained on warfarin presented with acute right middle cerebral artery (MCA) infarction manifesting as a left hemiplegia. An MRI revealed a complete occlusion of the right M1 segment with an area of restricted diffusion in the right basal ganglia representing only a small area of acute infarction. Patchy areas of subacute infarction were also present in the right MCA territory. He underwent endovascular mechanical thrombectomy with a stent retriever. This is an account of a successful mechanical thrombectomy performed in the youngest patient reported in the English literature to date.

Stidd, David A.

2014-01-01

39

A colo-urachal-cutaneous fistula in an 88-year-old male  

PubMed Central

Introduction Urachus anomalies are remnants of the urachus, an embryonic connection between the fetal bladder and umbilicus. These anomalies usually remain asymptomatic but can cause symptoms in case of infection. An extremely rare complication of symptomatic urachal remnants is fistulizing to adjacant viscera. We describe the first case of diverticulitis associated sigmoid-urachal-cutaneous fistula. Case report An 88-year-old male visited the outpatient clinic with intermittent bleeding and gassy discharge from his umbilicus. Examination showed a normal looking umbilicus with a small fissure at the bottom in which a 10 cm probe could be inserted. Laparotomy revealed a fistula extending from the umbilicus to a pus filled cyst superior to the bladder. A second fistula between the cyst and a mid-sigmoid diverticulum was identified. The involved sigmoid segment was resected. Pathological examination demonstrated no malignancy. Discussion Urachal remnants are extremely rare in adults. They typically present with abdominal pain or palpable masses. Additional imaging can aid the diagnostic process. Conclusion Due to the risk of recurrence and malignant transformation complete surgical excision of urachal anomalies is the treatment of choice. This can be done in a 1-step or 2-step procedure. PMID:22288045

Peters, Anna L.; Kruijer, Marjan J.P.; Wiese, Hans; Verbeek, Paul C.M.

2011-01-01

40

Pancreatic Tail Schwannoma in a 44-Year-Old Male: A Case Report and Literature Review  

PubMed Central

Pancreatic schwannomas are exceedingly uncommon neoplasms. According to a recent study in 2012, less than 50 cases of pancreatic schwannoma have been described in the English literature over the past thirty years. The vast majority of pancreatic schwannomas take place in the head and body of pancreas, respectively. Herein, we report the case of pancreatic tail ancient schwannoma in a 44-year-old man who presented with a 4-month history of epigastric pain. On physical examination, epigastric region was moderately tender to palpation without evidence of a palpable mass. All laboratory tests were normal. Contrast-enhanced computed tomography (CT) scan showed a 9.2 × 9.5 × 11.5?cm, huge, and well-defined left suprarenal mass arising either from adrenal gland, pancreas, or retroperitoneum. The mass demonstrated mild heterogeneous enhancement with central cystic/necrotic area. No evidence of distant metastasis was identified. At laparoscopy, the mass was noticed to originate from pancreatic tail. Patient underwent surgical resection of pancreatic tail. Microscopic and immunohistochemical examination of the pancreatic tail specimen showed ancient schwannoma. Patient received no adjuvant therapy. At a postoperative 6-month followup, patient was completely asymptomatic and CT scan imaging showed no evidence of tumor recurrence. Moreover, a literature review on pancreatic schwannomas is presented. PMID:24371534

Alshammari, Abdullah M.; Mohammed, Shamayel

2013-01-01

41

Renal Replacement in End-Stage Renal Disease Patients over 75 Years Old  

Microsoft Academic Search

Background: Over the last decade, the age of dialysis patients has been increasing steadily in several units in Canada. Our main objective was to assess prevalence, co-morbidity and outcome of ESRD patients over 75 years old at the beginning of dialysis treatment in our center. As a group, they were compared to younger dialysis patients treated simultaneously. Methods: In the

Isabelle Létourneau; Denis Ouimet; Marc Dumont; Vincent Pichette; Martine Leblanc

2003-01-01

42

Pancytopenia in a 70-year-old african-american male: an unusual presentation of a rare disease.  

PubMed

Hairy cell leukemia is a rare lymphoid neoplasm arising from mature B-lymphocytes. Clinically, the disease presents with splenomegaly and abdominal discomfort, frequent infections, fatigue and bleeding because of related cytopenias. Bone marrow biopsy is essential for diagnosis. Below we describe a case of a 70-year-old African-American male who presented to our hematology clinic complaining of fatigue. Clinical exam and computed tomography imaging did not reveal splenic enlargement. Blood work-up revealed pancytopenia and bone marrow was diagnostic for hairy cell leukemia.The patient was started on cladribine, with gradual improvement of his symptoms and blood count abnormalities. Therefore, it is essential to keep hairy cell leukemia in the differential of pancytopenia even in the absence of a splenomegaly. PMID:24782931

Mirrakhimov, Aibek E; Ali, Alaa M; Barbaryan, Aram; Anusim, Nwabundo; Saba, Raya; Kwatra, Shawn G; Hussain, Nasir; Zdunek, Teresita; Gilman, Alan D

2014-01-01

43

Suspected Anorexia Nervosa in a 75YearOld Institutionalized Male  

Microsoft Academic Search

A male resident of an Intermediate Care Facility maintained a weight of 85 lbs. despite aggressive inter-disciplinary intervention. Evaluation revealed eating behavior and personality patterns similar to those found in adolescents and younger adults who have been diagnosed as having anorexia nervosa. Historical data supplied by the patient and his family also lent support to the belief that this man

Judah L. Ronch

1985-01-01

44

Clinical outcome of thymic lymphoepithelioma-like carcinoma: Case report of a 14-year-old male  

PubMed Central

Thymic carcinoma is a rare type of cancer, which arises from the thymic epithelium and accounts for ~1–4% of anterior mediastinal tumors in the USA. It rarely occurs in children, and is rarer among adults. Thymic lymphoepithelioma-like carcinoma (LELC) is an uncommon subtype of thymic carcinoma in children, however, it is one of the common histological subtypes of thymic carcinoma in adults. In the present study, a 14-year-old male patient presented to the Tokyo Metropolitan Cancer and Infectious diseases Center, Komagome Hospital (Tokoyo, Japan) with chest pain due to a large anterior mediastinal mass. The patient was histologically diagnosed with thymic LELC via a needle biopsy specimen, which was obtained from the primary site and indicated the Epstein-Barr virus infection, whose markers are also associated with oncogenesis. Immunohistochemical analysis demonstrated positive staining for keratin (AE1/AE3), epithelial membrane antigen, and latent membrane protein-1 and negative staining for cluster of differentiation 5. Thus, the patient was diagnosed with metastatic thymic LELC. First-line chemotherapy comprising of a cisplatin- and adriamycin-based chemotherapy regimen achieved a partial response, however, the patient succumbed within 10 months of the initial diagnosis due to rapid disease progression and refractory to subsequent cycles of chemotherapy. Thus, the current study, as well as previously reported cases, demonstrates that pediatric patients with thymic LELC continue to have a poor prognosis. PMID:25295106

SEKIHARA, KUNIKO; OKUMA, YUSUKE; KAWAMOTO, HIROSHI; HOSOMI, YUKIO

2014-01-01

45

Four-Year-Olds' Beliefs about How Others Regard Males and Females  

ERIC Educational Resources Information Center

Children's awareness of how others evaluate their gender could influence their behaviours and well-being, yet little is known about when this awareness develops and what influences its emergence. The current study investigated culturally diverse 4-year-olds' ("N" = 240) public regard for gender groups and whether exposure to…

Halim, May Ling; Ruble, Diane N.; Tamis-LeMonda, Catherine S.

2013-01-01

46

Successful Remove of a Metal Axletree Causing Penile Strangulation in a 19-Year-Old Male by Degloving Operation  

PubMed Central

Penile strangulation caused by foreign bodies mostly occurs in adolescents and adult males. When it happens, foreign bodies are often not easy to be removed. Penile strangulation is a rarely described urological emergency, especially in the adolescent population. This paper demonstrates the successful removal of a metal axletree causing penile strangulation in a 19-year-old male with the help of degloving operation. PMID:22924045

Gan, Weidong; Yang, Rong; Ji, Changwei; Lian, Huibo; Guo, Hongqian

2012-01-01

47

Tongue cancer in young patients: case report of a 26-year-old patient  

PubMed Central

Introduction This article presents the case of a 26-year-old woman with tongue cancer. The median age at the diagnosis of the tongue’s cancer is 61?years. Only approximately 2% of patients are diagnosed before the age of 35. Case presentation Our patient survived acute myeloid leukemia (AML) before her second year. She had been having recurrent, poorly healing aphtae on the right side of the tongue for a period of months before the symptoms of the tongue cancer appeared. As a treatment a partial glossectomy was conducted on the right side and a neck dissection of levels I-III. Than a reconstruction of the tongue with a radialis free vascularised flap from left side was performed. Discussion It should be always looked for the causal factor in young patients with a neoplasm. There is strong evidence for second malignant neoplasms in survivors of childhood cancer. PMID:22583815

2012-01-01

48

[76-year old patient with suspected but not confirmed "idiopathic myelofibrosis"].  

PubMed

A 76-year old patient was referred to our Oncology Unit due to hepatosplenomegaly, anemia, thrombocytopenia, eosinophilia, elevation of lactat dehydrogenase and leucocytosis with occurrence of myeloid and erythroid precursors in the peripheral blood. Histopathological examination of the bone marrow and molecular genetics showing a c-kit-D816V-mutation confirmed the diagnosis of systemic mastocytosis without evidence of idiopathic myelofibrosis. After starting of prednisone treatment anemia, thromocytopenia and the patient's performance status rapidly improved. PMID:21877149

Feld, C; Spangenberger, H; Böhm, J; Meuthen, D; Meuthen, I

2011-11-01

49

Macular hole after laser in situ keratomileusis in a 26-year-old patient.  

PubMed

The purpose of this study is to describe the 26-year-old patient with developed macular hole after bilateral laser in situ keratomileusis (LASIK). A macular hole with sharp margins and irregular surface of surrounding retina appeared in the left eye of the female 26-year-old patient two months after LASIK for correction of myopia (followup of 6 months). Although the best corrected visual acuity (BCVA) after LASIK was 1.0, after the macular hole has developed BCVA became 0.5. After surgery, the final visual acuity recovered to 0.7. Macular hole may develop after LASIK for myopia correction due to unknown changes of vitreoretinal interface. Complete informed consent must be obtained from patients with high myopic eyes before LASIK. PMID:23840997

Bikbova, Guzel; Oshitari, Toshiyuki; Sakurai, Madoka; Baba, Takayuki; Yamamoto, Shuichi

2013-01-01

50

Macular Hole after Laser In Situ Keratomileusis in a 26-Year-Old Patient  

PubMed Central

The purpose of this study is to describe the 26-year-old patient with developed macular hole after bilateral laser in situ keratomileusis (LASIK). A macular hole with sharp margins and irregular surface of surrounding retina appeared in the left eye of the female 26-year-old patient two months after LASIK for correction of myopia (followup of 6 months). Although the best corrected visual acuity (BCVA) after LASIK was 1.0, after the macular hole has developed BCVA became 0.5. After surgery, the final visual acuity recovered to 0.7. Macular hole may develop after LASIK for myopia correction due to unknown changes of vitreoretinal interface. Complete informed consent must be obtained from patients with high myopic eyes before LASIK. PMID:23840997

Oshitari, Toshiyuki; Sakurai, Madoka; Baba, Takayuki; Yamamoto, Shuichi

2013-01-01

51

Nasogastric tube syndrome: a life-threatening laryngeal obstruction in a 72-year-old patient  

Microsoft Academic Search

Nasogastric tube (NGT) syndrome is a rarely reported complication of NGT use that can cause life-threatening laryngeal obstruction. The syndrome results from post-cricoid ulceration, which affects the posterior cricoarytenoid muscles, thus causing vocal cord abduction paralysis and upper airway obstruction. We describe a case of a 72-year-old patient with this syndrome who was treated successfully and emphasise the difficulty of

ESTHER-LEE MARCUS; YEHEZKEL CAINE; KASEM HAMDAN; MENACHEM GROSS

52

Correlates of weight loss and muscle-gaining behavior in 10- to 14-year-old males and females  

Microsoft Academic Search

Background. This study examined the influence of appearance and social acceptance esteem, awareness and internalization of media stereotypes, body size acceptance, and teasing on the weight loss and muscle-gaining behaviors of 10- to 14-year-old boys and girls.Methods. Male (n = 670) and female (n = 788) students were drawn from one of four public senior middle schools (grades 6–8) in

Gail McVey; Stacey Tweed; Elizabeth Blackmore

2005-01-01

53

Strong ERG Positivity in Papillary Intralymphatic Angioendothelioma of the Testis of a 24-Year-Old Male: A Case Report.  

PubMed

Papillary intralymphatic angioendothelioma is a rare, low-grade neoplasm of lymphatic channels that usually presents intradermally or subcutaneously. We report the case of a 24-year-old male presenting with an isolated intratesticular palpable mass and symptoms of testicular pain. Preoperative ultrasound examination showed an irregular, heterogeneous mass. Subsequent surgery and pathologic assessment revealed a papillary intralymphatic angioendothelioma (PILA), formerly known as Dabska tumor within the lymphatic spaces. PMID:23607024

Schultheis, Anne M; Sandmann, Mareike; Steurer, Stefan

2013-01-01

54

Human papillomavirus vaccine uptake among 9–17 year old males in the United States  

PubMed Central

In 2009, a quadrivalent HPV vaccine was approved and “permissively” recommended for US males aged 9 to 26 y to protect against genital warts. The purpose of this study was to examine parental awareness and HPV vaccine uptake among 9–17 y old males during the first year following this recommendation. Data from the 2010 National Health Interview Survey (NHIS) were obtained to assess vaccination status (n = 2973) of this age group. Univariate logistic regression analysis was performed to examine correlates of parental awareness and uptake of the HPV vaccine. Overall, 55% of parents with sons were aware of the HPV vaccine. The likelihood of parental awareness was lower among minorities and adolescents with low family incomes, and higher among adolescents with insurance, higher parental education, and those who had a well-child check up and dental examination in the past year than their counterparts. Only 2.0% and 0.5% of 9–17 y old males initiated (? 1 dose) and completed (? 3 doses) the vaccine series, respectively. Adolescents with a Hispanic origin (odds ratio (OR) 2.03, 95% confidence interval (CI) 1.09–3.78), low family income (OR 2.89, 95% CI 1.48 -5.57), and history of influenza vaccination in the past year (OR 1.89, 95% CI 1.11 -3.22) were more likely than their counterparts to initiate the HPV vaccine. On the other hand, adolescents with private insurance (OR 0.44, 95% CI 0.20 -0.94) and those who had college educated parents (OR 0.45, 95% CI 0.22 -0.89) were less likely to initiate the vaccine. This study showed that very few adolescent males received any doses of HPV vaccine during the first year following its recommendation for this gender. Thus, interventional programs are needed to improve vaccine uptake among adolescent males. PMID:23295743

Laz, Tabassum H.; Rahman, Mahbubur; Berenson, Abbey B.

2013-01-01

55

Noninvasive assessment of cardiomyopathy in normotensive diabetic patients between 20 and 50 years old  

SciTech Connect

To further the understanding of diabetic heart disease, we tested the hypothesis that an asymptomatic group of normotensive diabetic patients between 20 and 50 years old had a restrictive cardiomyopathy independent of clinically significant coronary artery disease. Quantitative two-dimensional echocardiography and stress myocardial perfusion scintigraphy were performed to detect and characterize the cardiac abnormalities in this study group comprising 88 patients with rigorously classified diabetes and 65 volunteer control subjects. Diabetic patients were shown to have a mildly reduced left ventricular end-diastolic volume index: 50.1 +/- 8.2 and 52.1 +/- 14.7 mL/m2 for patients with type I and type II diabetes, respectively, versus 58.9 +/- 11.7 mL/m2 for control subjects. The left ventricular diastolic filling was also impaired in diabetic patients as reflected by a lower atrial emptying index: 0.73 +/- 0.24 and 0.76 +/- 0.3 for type I and type II diabetics, respectively, compared with 1.14 +/- 0.24 for control subjects. Exercise tolerance was normal in subjects with type I diabetes and slightly reduced in subjects with type II diabetes. Only one patient developed regional ischemia on thallium exercise testing. Using a comprehensive, noninvasive approach, we have shown that asymptomatic normotensive patients with type I or type II diabetes who were between 20 and 50 years old had a restrictive cardiomyopathy characterized by mildly reduced left ventricular end-diastolic volume and altered left ventricular compliance independent of critical coronary artery disease.

Bouchard, A.; Sanz, N.; Botvinick, E.H.; Phillips, N.; Heilbron, D.; Byrd, B.F. 3d.; Karam, J.H.; Schiller, N.B. (Univ. of California, San Francisco (USA))

1989-08-01

56

Cardiovascular responses to light isometric and aerobic exercise in 21- and 59-year-old males  

Microsoft Academic Search

The effects of aging on the cardiovascular response to continuous light isometric and aerobic exercise remains to be determined.\\u000a Thus, the purpose of this study was to compare the cardiovascular response of young and older males during light handgrip\\u000a and cycle ergometry exercise. Blood pressure, heart rate, rate pressure product, as well as pre-ejection period (derived from\\u000a impedance cardiography) were

Stephen H. Boutcher; Dean Stocker

1999-01-01

57

[Myocardial revascularization surgery in an 87-year-old patient. A case report].  

PubMed

A 87 years old patient, with independent life style, presented unstable angina in spite of medication. Cineangiocoronariography demonstrated severe triarterial lesions, with good distal segments and preserved left ventricular contractility. Three saphenous vein grafts were performed. Some clinical measures were employed: a) manitol, furosemide and Ringer solution were infused two hours before and during surgery; the infusion was maintaned during the two postoperative days; b) limited use of nephrotoxic agents; c) adequate doses of medication; d) red cells infusion in spite of higher hematocrit levels than those present in younger patients; e) early start of respiratory physiotherapy and deambulation. Mean arterial pressure was maintained over 80 mm/Hg during surgery. During the period of extracorporeal circulation a hollow capillary membrane oxygenador was employed. Immediate postoperative course, up till six months, was free of coronary insufficiency symptoms. This case demonstrates the benefits of myocardial revascularization in elderly patients, respecting some peculiarities of the geriatric therapeutics. PMID:2629674

Wajngarten, M; Jatene, F B; Bosisio, I B; Azul, L G; Pileggi, F J; Jatene, A D

1989-09-01

58

Macular telangiectasia type 2 (MacTel) in a 34-year-old patient.  

PubMed

We report macular telangiectasia type 2 (MacTel) in a 34-year-old man, the youngest patient so far published with MacTel type 2. The patient presented with metamorphopsia and impaired reading ability. Diagnosis was based on bilateral abnormal macular autofluorescence, perifoveal telangiectasia with fluorescein angiographic hyperfluorescence without cystoid oedema, a small foveal avascular zone, asymmetric configuration of the foveal pit, disruptions in the inner segment/outer segment layer and hyper-reflective haze and spots in the outer nuclear layer. Although MacTel usually manifests with a slowly progressive decrease in visual acuity in the fifth to seventh decades of life, younger patients may occasionally be diagnosed with the disease. Awareness of subtle signs of the condition is essential for early diagnosis. PMID:25249218

Nicolai, Heleen; Wirix, Mieke; Spielberg, Leigh; Leys, Anita

2014-01-01

59

Bladder Cancer versus Hemorrhagic Cystitis: A Case of Mistaken Identity in a 34-Year-Old Male Undergoing Therapy for Granulomatosis with Polyangiitis  

PubMed Central

A 34-year-old male was referred for management of bladder cancer noted on workup for gross hematuria and new-onset irritative voiding symptoms. The patient's history was significant for recently diagnosed granulomatosis with polyangiitis for which he was undergoing treatment with oral cyclophosphamide and corticosteroids. Cystoscopy revealed lesions suspicious for malignancy, but the patient was diagnosed with hemorrhagic cystitis secondary to BK virus infection upon cytology review, and immunostaining confirmed a polyomavirus infection of the urothelium. The patient's symptoms resolved after a modification of his immunosuppressive regimen, and antiviral therapy was ultimately unnecessary. Though symptomatic BK virus infection of the genitourinary tract is common in immunosuppressed transplant patients, its occurrence in a patient undergoing immunomodulation for an autoimmune disease has not been reported yet. This case illustrates the potential for active BK virus infections in atypical patient populations and underscores the importance of rigorous hematuria workup, particularly in patients with multiple risk factors. PMID:25028586

Amatruda, Jonathan; Dieckhaus, Kevin; Hegde, Poornima; Taylor, John

2014-01-01

60

A Case of Ocular Syphilis in a 36-Year-Old HIV-Positive Male  

PubMed Central

The incidence of syphilis in the United States has increased markedly over the last decade, particularly among men who have sex with men (MSM). Although uncommon, ocular involvement is a potentially devastating clinical manifestation of syphilis. Human immunodeficiency virus (HIV) infection appears to increase the risk of ocular syphilis. Because of the lack of pathognomonic features for ocular syphilis and its ability to occur in both immunocompetent and immunosuppressed individuals, prompt diagnosis requires a high index of suspicion. Ocular syphilis should therefore be considered in MSM and HIV-infected patients presenting with unexplained visual complaints. Herein, we present a case of ocular syphilis in a patient with newly diagnosed HIV.

Jenkins, Timothy C.

2014-01-01

61

Pathology Case Study: Intermittent Fevers in a 43-Year-Old Black Male  

NSDL National Science Digital Library

The University of Pittsburgh School of Medicine's Department of Pathology has compiled a series of case studies to help students and instructors. In this particular study the patient is complaining of intermittent fevers. The case provides test results and data as well as microscopic photos and description. Clicking on the final diagnosis provides a thorough explanation of the diagnosis as well as treatment.

Dorvault, Christine; Richert, Charles A.

2007-08-12

62

Mature (Benign) Cystic Retroperitoneal Teratoma Involving the Left Adrenal Gland in a 22-Year-Old Male: A Case Report and Literature Review  

PubMed Central

Primary retroperitoneal teratomas involving adrenal glands are exceedingly uncommon accounting for only 4% of all primary teratomas. They are more common in childhood and rarely occur in adults. Only a very few case reports have been documented in literature so far. Herein, we report a mature (benign) cystic retroperitoneal teratoma in the region of left adrenal gland in a 22-year-old otherwise healthy male patient who presented with a 1-month history of left flank pain. In addition, a literature review on teratomas is included. PMID:23762690

2013-01-01

63

Synthetic cannabinoid overdose in a 20-year-old male US soldier.  

PubMed

Popularity of synthetic cannabinoids among US military service members has risen over the last several years, leading to an increase in hospitalizations and legal actions stemming from its use and possession. Although synthetic cannabinoids, collectively referred to as "Spice," are similar in structure to the active metabolites found in cannabis, significant concerns exist regarding the severity of short- and long-term medical and psychiatric sequelae. This article presents a case, in which a patient experienced severe medical and psychiatric symptoms far exceeding the severity and duration typically resulting from cannabis use. PMID:23327506

Berry-Cabán, Cristóbal S; Ee, Juliana; Ingram, Victoria; Berry, Carlos E; Kim, Eugene H

2013-01-01

64

[Pulmonary infiltrates with blood eosinophilia in a 62-year-old patient].  

PubMed

A 62-year-old woman was admitted because of chronic cough and bilateral infiltrates on chest roentgenogram. Additional history revealed that the patient had been taken diclofenac emulgel during the previous 10 years for arthrosis. Diagnostic bronchoscopy showed eosinophilic alveolitis. After ruling out infectious, parasitic or systemic diseases drug-induced eosinophilic pneumonia was diagnosed due to topical diclofenac therapy and subsequent percutaneous drug absorption. No previous case of eosinophilic pneumonia to topical diclofenac was discovered in our review of the literature. The diclofenac therapy was discontinued. Oral corticosteroid therapy cleared bilateral infiltrates on CT scan within seven days. Drug reactions are the most common cause of pulmonary infiltrates with blood eosinophilia and/or eosinophilic alveolitis and should be considered as a differential diagnosis. PMID:14671818

Kohlhäufl, M; Weber, N; Morresi-Hauf, A; Geiger, D; Raith, H; Häussinger, K

2003-08-01

65

Rhabdomyolysis and Cardiomyopathy in a 20-Year-Old Patient with CPT II Deficiency  

PubMed Central

Aim. To raise the awareness of adult-onset carnitite palmitoyltransferase II deficiency (CPT II) by describing clinical, biochemical, and genetic features of the disease occurring in early adulthood. Method. Review of the case characteristics and literature review. Results. We report on a 20-year-old man presenting with dyspnea, fatigue, fever, and myoglobinuria. This was the second episode with such symptoms (the previous one being three years earlier). The symptoms occurred after intense physical work, followed by a viral infection resulting in fever treated with NSAIDs. Massive rhabdomyolysis was diagnosed, resulting in acute renal failure necessitating plasmapheresis and hemodialysis, acute hepatic lesion, and respiratory insufficiency. Additionally, our patient had cardiomyopathy with volume overload. After a detailed workup, CPT II deficiency was suspected. We did a sequencing analysis for exons 1, 3, and 4 of the CPT II gene and found that the patient was homozygote for Ser 113 Leu mutation in exon 3 of the CPT II gene. The patient recovery was complete except for the cardiomiopathy with mildly impaired systolic function. Conclusion. Whenever a patient suffers recurrent episodes of myalgia, followed by myoglobinuria due to rhabdomyolysis, we should always consider the possibility of this rare condition. The definitive diagnose of this condition is achieved by genetic testing. PMID:24563797

Vavlukis, M.; Eftimov, A.; Zafirovska, P.; Caparovska, E.; Pocesta, B.; Kedev, S.; Dimovski, A. J.

2014-01-01

66

Rhabdomyolysis and Cardiomyopathy in a 20-Year-Old Patient with CPT II Deficiency.  

PubMed

Aim. To raise the awareness of adult-onset carnitite palmitoyltransferase II deficiency (CPT II) by describing clinical, biochemical, and genetic features of the disease occurring in early adulthood. Method. Review of the case characteristics and literature review. Results. We report on a 20-year-old man presenting with dyspnea, fatigue, fever, and myoglobinuria. This was the second episode with such symptoms (the previous one being three years earlier). The symptoms occurred after intense physical work, followed by a viral infection resulting in fever treated with NSAIDs. Massive rhabdomyolysis was diagnosed, resulting in acute renal failure necessitating plasmapheresis and hemodialysis, acute hepatic lesion, and respiratory insufficiency. Additionally, our patient had cardiomyopathy with volume overload. After a detailed workup, CPT II deficiency was suspected. We did a sequencing analysis for exons 1, 3, and 4 of the CPT II gene and found that the patient was homozygote for Ser 113 Leu mutation in exon 3 of the CPT II gene. The patient recovery was complete except for the cardiomiopathy with mildly impaired systolic function. Conclusion. Whenever a patient suffers recurrent episodes of myalgia, followed by myoglobinuria due to rhabdomyolysis, we should always consider the possibility of this rare condition. The definitive diagnose of this condition is achieved by genetic testing. PMID:24563797

Vavlukis, M; Eftimov, A; Zafirovska, P; Caparovska, E; Pocesta, B; Kedev, S; Dimovski, A J

2014-01-01

67

Congenital insensitivity to pain with anhidrosis: a case report of a 33-year-old patient.  

PubMed

Congenital insensitivity to pain with anhidrosis is a type IV hereditary sensory and autonomic neuropathy, presenting early in life. This disorder results from defective neural crest differentiation with loss of the first-order afferent system, which is responsible for sensations of pain and temperature; a neuronal loss in the sympathetic ganglia is also present. A case of a 33-year-old patient with congenital insensitivity to pain with anhidrosis is presented. From the time of birth, he did not sweat and did not respond to painful stimuli, although unexplained bouts of fever were often observed in infancy; an extensive workup during childhood helped establish the diagnosis. Throughout childhood and adulthood, the patient presented multiple infections and fractures in various sites of his body, growth disturbances, and avascular necrosis, and Charcot arthropathies and joint dislocations mainly affected his elbow and hip joint. At the final follow-up, at the age of 33 years, he was found to be obese, with a limited social life. A Charcot elbow restricted the activity of his left upper limb, and the dislocated hips combined with the instability of the ankle joints limited the ambulation distance. A specific treatment protocol has not been established in the literature; the main principles that can be applied in patients with normal intelligence include training programs to prevent self-mutilation and accidental injuries and an early diagnosis and treatment of the infections. PMID:22422007

Kosmidis, Ilias; Krallis, Panagiotis; Tsiamasfirou, Damiani; Filiopoulos, Konstantinos

2013-01-01

68

Annular Pancreas: A Cause of Gastric Outlet Obstruction in a 20-Year-Old Patient  

PubMed Central

Patient: Female, 20 Final Diagnosis: Annular pancreas Symptoms: Food intolerance • vomiting Medication:— Clinical Procedure: — Specialty: Gastroenterology and Hepatology Objective: Congenital defects/diseases Background: Annular pancreas is a congenital anomaly that consists of a ring of pancreatic tissue partially or completely encircling the descending portion of the duodenum. It is formed due to the failure of the ventral bud to rotate, thus it elongates and encircles the upper part of the duodenum. It can present in a wide range of clinical severities, and can affect neonates to the elderly, making it difficult to diagnosis. Although diagnosis of annular pancreas can be made pre-operatively by upper GI series, upper GI endoscopy, or CT scan, 40% of diagnoses require surgery for confirmation. Case Report: We report the case of a 20-year-old woman presenting with history of vomiting and weight loss since childhood. We present the clinical characteristics, surgical management in the form of bypass procedure done through a duodenojujenostomy, and follow-up of the patient. Conclusions: Annular pancreas occasionally presents in adults. Variable presentations have been described in the literature, including pancreatic neoplasm, pancreatitis, obstructive jaundice, duodenal obstruction, and peptic ulcer diseases. Most studies of these lesions are single case reports or small series, which do not allow a surgeon to accumulate extensive experience; therefore, reliance on the combined experience of others in recognition and appropriate management has been the norm. PMID:25300027

Alahmadi, Raha; Almuhammadi, Saud

2014-01-01

69

Acute unintentional intoxication with paraffin in a 25-year old patient - clinical case report.  

PubMed

"Fire-breathing" or "fire-eating" is a special kind of street art where the acts are always stunning, spectacular and amazing. People exhibiting this kind of show are professionals, not rare amateurs, who use different kind of fuels, usually hydrocarbons, in order to produce a pillar of fire. Intoxications caused by ingestion or inhalation of liquid paraffin, used as a fuel while performing, are numerous and various. We present a clinical case report of a 25-year old, previously healthy, amateur "fire-breather". During October, 2010 this young men arrived at the Emergency Unit of the University Clinic for toxicology and Urgent Internal Medicine in a severe clinical condition, after his unsuccessful attempt to perform real "fire-breathing". He had fever, strong headaches, mild abdominal and chest pain and he also had difficulties breathing and persistent dry cough. The patient was extremely dyspneic with peripheral cyanosis and shortness of breath. "Fire-breathers" must be viewed as a population at risk of paraffin-induced pneumonia, which has low mortality rate, but still is related with numerous and various chronic complications. Our patient was first in a life threatening, extremely serious clinical condition which was urgently treated with appropriate vigorous and effective therapy. This therapeutic protocol led to successful full recovery of these young men, who luckily didn't exhibit any chronic complications. PMID:25066163

Chibishev, Andon; Simonovska, Natasa

2014-08-01

70

Multiple supernumerary teeth in a nonsyndromic 12-year-old female patient - a case report.  

PubMed

Supernumerary teeth (ST) are uncommon alterations of development that may appear in either of the dental arches and that are frequently associated with syndromes such as cleidocranial dysplasia and Gardner syndrome. Multiple ST in individuals with no other disease or syndrome are very rare. In view of this situation, correct diagnosis, treatment and evaluation of ST with the use of appropriate imaging techniques are highly important. This case report presents radiographic images of a nonsyndromic 12-year-old female patient who presented with 14 supernumerary teeth and was treated under general anesthesia, with the extraction of all ST in a single surgical intervention. During the postoperative period, the patient did not complain of pain nor did she present any signs or symptoms of infection. During late follow-up period, due to difficulty in traction of the maxillary right canine and mandibular left first premolar towards the dental arch, it was necessary to extract these teeth under local anesthesia. Radiographic examination 3 years after surgery revealed the absence of ST and of diseases related to the existence of these teeth. PMID:24789298

Santos, Thiago de Santana; Silva, Erick Ricardo; Faria, Ana Célia; Mello Filho, Francisco Veríssimo de; Xavier, Samuel Porfírio

2014-01-01

71

Annular pancreas: a cause of gastric outlet obstruction in a 20-year-old patient.  

PubMed

Background Annular pancreas is a congenital anomaly that consists of a ring of pancreatic tissue partially or completely encircling the descending portion of the duodenum. It is formed due to the failure of the ventral bud to rotate, thus it elongates and encircles the upper part of the duodenum. It can present in a wide range of clinical severities, and can affect neonates to the elderly, making it difficult to diagnosis. Although diagnosis of annular pancreas can be made pre-operatively by upper GI series, upper GI endoscopy, or CT scan, 40% of diagnoses require surgery for confirmation. Case Report We report the case of a 20-year-old woman presenting with history of vomiting and weight loss since childhood. We present the clinical characteristics, surgical management in the form of bypass procedure done through a duodenojujenostomy, and follow-up of the patient. Conclusions Annular pancreas occasionally presents in adults. Variable presentations have been described in the literature, including pancreatic neoplasm, pancreatitis, obstructive jaundice, duodenal obstruction, and peptic ulcer diseases. Most studies of these lesions are single case reports or small series, which do not allow a surgeon to accumulate extensive experience; therefore, reliance on the combined experience of others in recognition and appropriate management has been the norm. PMID:25300027

Alahmadi, Raha; Almuhammadi, Saud

2014-01-01

72

Hemolytic Uremic Syndrome in a 65-Year-Old Male Linked to a Very Unusual Type of stx2e- and eae-Harboring O51:H49 Shiga Toxin-Producing Escherichia coli  

PubMed Central

We report on a 65-year-old male patient with a Shiga toxin-producing Escherichia coli O51:H49 gastrointestinal infection and sepsis associated with hemolytic uremic syndrome (HUS) with a fatal outcome. The strains isolated harbored stx2e and eae, a very unusual and new virulence profile for an HUS-associated enterohemorrhagic E. coli. PMID:24501025

Fasel, Dominique; Mellmann, Alexander; Cernela, Nicole; Hachler, Herbert; Fruth, Angelika; Khanna, Nina; Egli, Adrian; Beckmann, Christiane; Hirsch, Hans H.; Goldenberger, Daniel

2014-01-01

73

Hemolytic uremic syndrome in a 65-Year-old male linked to a very unusual type of stx2e- and eae-harboring O51:H49 shiga toxin-producing Escherichia coli.  

PubMed

We report on a 65-year-old male patient with a Shiga toxin-producing Escherichia coli O51:H49 gastrointestinal infection and sepsis associated with hemolytic uremic syndrome (HUS) with a fatal outcome. The strains isolated harbored stx2e and eae, a very unusual and new virulence profile for an HUS-associated enterohemorrhagic E. coli. PMID:24501025

Fasel, Dominique; Mellmann, Alexander; Cernela, Nicole; Hächler, Herbert; Fruth, Angelika; Khanna, Nina; Egli, Adrian; Beckmann, Christiane; Hirsch, Hans H; Goldenberger, Daniel; Stephan, Roger

2014-04-01

74

A 17-year-old male with pseudotumor cerebri secondary to performance-enhancing steroids triggering venous thrombosis in the brain.  

PubMed

This article is a case report of a 17-year-old male who presented with a headache and blurry vision. He subsequently was noted to have papilledema on a fundoscopic examination and an initial normal magnetic resonance imaging and computed tomography of his head; his condition was, therefore, diagnosed as pseudotumor cerebri. A subsequent magnetic resonance venography of his head revealed venous thrombosis, and other investigations revealed an elevated factor VIII level as well as a mutation at the MTHFR locus, consistent with an elevated risk for hypercoagulability. In addition, he admitted to steroid usage for purposes of performance enhancement in baseball. The patient's condition eventually improved with acetazolamide and serial lumbar punctures. Steroids have been linked to predisposition to hypercoagulable states, but there are no reports identified by these authors that link performance-enhancing steroids with pseudotumor cerebri as a result of a coagulation dyscrasia. PMID:19131586

DeSena, Allen D; Weimer, Stephen

2009-03-01

75

[19-year-old asthma patient with pronounced eosinophilia and acute coronary syndrome].  

PubMed

Diagnosis of Churg-Strauss syndrome should be considered in young asthmatics with fatigue and eosinophilia. On the base of the etiopathology of a 19-year old man, who was initially admitted because of dyspnoea, fever and acute chest pain, we show that eosinophilia gives an important hint for further diagnostic and is the key trend parameter. Histologically an eosinophilic myocarditis could be shown in the myocardial biopsy. High dose prednisolone induced a clear improvement in symptoms, with decrease of the inflammatory signs and the eosinophilia and a clear improvement of the left ventricular function. PMID:21505837

Tränkner, A; Hass, N; Simonis, G; Braun-Dullaeus, R; Geiger, K; Strasser, R H

2011-12-01

76

Males Have Greater "g": Sex Differences in General Mental Ability from 100,000 17- to 18-Year-Olds on the Scholastic Assessment Test  

ERIC Educational Resources Information Center

In this study we found that 17- to 18-year old males averaged 3.63 IQ points higher than did their female counterparts on the 1991 Scholastic Assessment Test (SAT). We analysed 145 item responses from 46,509 males and 56,007 females (total N = 102,516) using a principal components procedure. We found (1) the "g" factor underlies both the SAT…

Jackson, Douglas N.; Rushton, J. Philippe

2006-01-01

77

[Sore throat and subcutaneous emphysema in a 71-year-old patient].  

PubMed

A 71-year-old woman was admitted to our emergency department due to sore throat and swelling of the neck and face. She had a history of chronic obstructive pulmonary disease grade 4 based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Clinical examination revealed subcutaneous emphysema of the neck and face. CT scan of the thorax and abdomen showed air in the retroperitoneum, ascending through the mediastinum into the neck and face. Laparotomy confirmed the diagnosis of a retroperitoneal colon perforation due to colon diverticulitis. The colon was partially removed followed by a surgical debridement and Hartmann's procedure. The postoperative course was without complications, the clinical symptoms resolved rapidly. PMID:25056733

Floer, M; Röming, H; Rastan, M; Dörner, H; Meister, T

2014-10-01

78

[Aseptic, simultaneous and bilateral mobilisation due to an acetabular shell fracture in a 43 year-old patient].  

PubMed

The acetabular shell mobilization is the main long-term complication in total hip replacement. Metal-back fracture has also to be considered among the possible causes of shell mobilization. A case is presented of bilateral acetabular shell mobilization due to the trabecular covering de-soldering from the metal-back in a 43 year-old patient, 13-14 years after the first surgery. PMID:24360788

Ceretti, M; Fanelli, M; Pappalardo, S

2014-01-01

79

Arteriovenous fistula of the kidney: a case report of 47-year-old female patient treated by embolisation.  

PubMed

Arteriovenous fistulas of the kidney are rare. They may be acquired, idiopathic or arise in congenital arteriovenous malformations. There are only few reports in the current literature describing the successful embolisation of idiopathic arteriovenous fistulas. We report a 47-year-old hypertensive female patient with a successfully embolised arteriovenous fistula. Diagnosis was made on the basis of colour duplex Doppler examination and this method enabled further successful embolisation of the fistula. PMID:12692574

Paschalis-Purtak, K; Januszewicz, M; Rokicki, A; Puci?owska, B; Imiela, J; Cybulska, I; Cie?la, W; Prejbisz, A; Szostek, M; Januszewicz, A

2003-04-01

80

The impact of young age on locoregional recurrence after doxorubicin-based breast conservation therapy in patients 40 years old or younger: How young is 'young'?  

SciTech Connect

Purpose: The aim of this study was to investigate whether patients <35 years old have similar risk of locoregional recurrence after breast conservation therapy compared with patients 35 to 40 years old. Methods and materials: We retrospectively reviewed records of 196 consecutive patients {<=}40 years old who received breast conservation therapy (BCT) from 1987 to 2000 for breast cancer and compared outcomes between patients <35 years old with patients 35 to 40 years old. The majority of patients received neoadjuvant chemotherapy as part of their treatment. Multivariate analysis was performed to assess risk factors for locoregional recurrence. Results: After a median follow-up of 64 months, 22 locoregional recurrences (LRR) were observed. Twenty patients developed locoregional recurrence as their first site of relapse. Two patients had bone-only metastases before their locoregional recurrence. On multivariate analysis, age <35 years was associated with a statistically significant increased risk of locoregional recurrence. The 5-year rate of locoregional control was 87.9% in patients <35 years old compared with 91.7% in patients 35 to 40 years old (p = 0.042). Conclusions: Our finding supports an increased risk of locoregional recurrence as a function of younger age after breast conservation therapy, even among young patients 40 years old and younger.

Oh, Julia L. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)]. E-mail: joh@mdanderson.org; Bonnen, Mark [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Outlaw, Elesyia D. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Schechter, Naomi R. [Department of Radiation Oncology, University of California-San Francisco Mt. Zion Comprehensive Cancer Center, San Francisco, CA (United States); Perkins, George H. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Strom, Eric A. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Babiera, Gildy [Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Oswald, Mary Jane [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Allen, Pamela K. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Thames, Howard D. [Department of Biostatistics and Applied Mathematics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Buchholz, Thomas A. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)

2006-08-01

81

Radiographically Negative, Asymptomatic, Sentinel Lymph Node Positive Cutaneous T-Cell Lymphoma in a 3-Year-Old Male: A Case Report  

PubMed Central

We present a case of a 3-year-old male originally diagnosed with a CD30+ anaplastic cutaneous T-cell lymphoma with no evidence of systemic disease after CT scan, PET scan, and bone marrow aspiration. Sentinel lymph node biopsy (SLNB) was performed as an additional step in the workup and showed microscopic disease. Current management/recommendations for cutaneous T-cell lymphoma do not include SLNB. Medical and surgical management of cutaneous malignancies is dramatically different for local versus advanced disease. Therefore adequate evaluation is necessary to properly stage patients for specific treatment. Such distinction in extent of disease suggests more extensive therapy including locoregional radiation and systemic chemotherapy versus local excision only. Two international case reports have described SLNB in cutaneous T-cell lymphoma with one demonstrating evidence of node positive microscopic disease despite a negative metastatic disease workup. This case is being presented as a novel case in a child with implications including lymphoscintigraphy and SLNB as a routine procedure for evaluation and staging of cutaneous T-cell lymphoma if the patient does not demonstrate evidence of metastatic disease on routine workup. PMID:23150841

Carson, Jeffrey; Bedrnicek, Jiri; Abdessalam, Shahab

2012-01-01

82

Verocytotoxin-Producing Escherichia coli O128ab:H2 Bacteremia in a 27-Year-Old Male with Hemolytic-Uremic Syndrome  

PubMed Central

Verocytotoxin-producing Escherichia coli (VTEC) strains of serotype O128ab:H2 were isolated from blood and stool of a 27-year-old male presenting diarrhea-associated hemolytic-uremic syndrome complicated by bacteremia. This report once again illustrates the pathogenic potential of a non-O157 VTEC strain carrying a virulence profile previously associated with mild disease. PMID:23467596

Buvens, Glenn; De Rauw, Klara; Roisin, Sandrine; Vanfraechem, Gaelle; Denis, Olivier; Jacobs, Frederique; Scheutz, Flemming

2013-01-01

83

Attitudes toward homosexual activity and gays as friends: A national survey of heterosexual 15? to 19?year?old males  

Microsoft Academic Search

Heterosexual adolescent males’ negative attitudes toward gays were examined using data from a 1988 national survey of male youth 15 to 19 years of age. Results indicated that the vast majority of young males, 89%, found sex between two men “disgusting,” and only 12% felt confident that they could befriend a gay person. Multivariate analyses revealed, as expected, that respondents

William Marsiglio

1993-01-01

84

Diagnosis and treatment of a 16-year-old Chinese patient with concurrent hereditary hemochromatosis and Gilbert's syndrome.  

PubMed

Gilbert's syndrome and hereditary hemochromatosis predominantly affect Caucasians with a low incidence in Asians. Here we report the case of a 16-year-old Chinese boy, who was admitted with hepatalgia, jaundice, hyperpigmentation, and splenomegaly to our hospital. After excluding chronic hepatitis, autoimmune disorders, and alcohol or drug injury, genetic analyses of the patient and his parents revealed simultaneous manifestations of Gilbert's syndrome and hereditary hemochromatosis, though his parents did not develop related symptoms. The presented case indicates that diagnoses of Gilbert's syndrome and hereditary hemochromatosis should be taken into consideration when chronic hepatitis is suspected without a clear etiology. PMID:25262004

Wang, Xianbo; Liu, Yanmin; Chang, Yujuan; Liu, Huimin; Wang, Peng

2014-01-01

85

[Veno-arterial ECMO as bridge to recovery. Cardiogenic shock and suspected myocarditis in a 37-year-old patient].  

PubMed

We report a case of a 37-year-old patient presenting with fulminant cardiogenic shock, almost noncontractile ventricles, followed by electromechanical dissociation. During performance of cardiopulmonary resuscitation, a veno-arterial extracorporeal membrane oxygenation device (VA ECMO) was implanted, which became necessary for 13 days. Subsequently, a total arrest of ventricular function was observed and prominent multiple organ failure emerged. A rapid test for respiratory syncytial virus was positive, supporting the suspected diagnosis of myocarditis. Despite numerous complications, complete recovery was achieved. PMID:22349535

Fox, H; Seeger, F H; Schmitt, J; Potente, M; Dzemali, O; Fichtlscherer, S; Ehrlich, J R

2012-04-01

86

Significance of radical cystectomy for bladder cancer in patients over 80 years old  

Microsoft Academic Search

Objectives  The objective of this study was to evaluate the usefulness of radical cystectomy for bladder cancer in elderly patients.\\u000a \\u000a \\u000a \\u000a Materials and methods  This study included 72 patients aged ?80 years (group A) who underwent radical cystectomy and urinary diversion between January\\u000a 1995 and December 2003, and the clinical outcome of these patients were compared with those of 557 patients aged <80 years\\u000a (group B)

Kazuki Yamanaka; Hideaki Miyake; Isao Hara; Taka-aki Inoue; Masato Fujisawa

2007-01-01

87

Performance measures of 16– to 86-year-old males and females on the auditory verbal learning test  

Microsoft Academic Search

This study reports Auditory Verbal Learning Test (AVLT) data for 153 adults in age groups spanning seven decades, with approximately equal numbers of males and females and matched for intelligence, education, and occupation. Overall performance deteriorated with increased age, females performing better than males. Older subjects recalled fewer words, were more susceptible to information overload during input, showed diminished retrieval

Gina Geffen; K. J. Moar; A. P. Ohanlon; C. R. Clark; L. B. Geffen

1990-01-01

88

Repair of a Large Main Pulmonary Artery Aneurysm in a 71-Year-Old Jehovah's Witness Patient  

PubMed Central

Pulmonary artery aneurysm is a rarely reported and poorly studied entity; most mentions in the literature are in case series and case reports. Cardiac surgery in Jehovah's Witness patients is occurring more frequently because of improved techniques of blood conservation. We report the repair of a large pulmonary artery aneurysm in a 71-year-old woman who was a Jehovah's Witness. Using total cardiopulmonary bypass, we replaced the main pulmonary artery and both branches with Gelweave tube-grafts, because the fragility of a homograft presented possible bleeding problems. The patient recovered rapidly, and her symptoms were greatly improved. We think that a patient's status as a Jehovah's Witness need not preclude potentially life-saving cardiac operations. PMID:23914038

Henn, Lucas W.; Esmailian, Fardad

2013-01-01

89

Repair of a large main pulmonary artery aneurysm in a 71-year-old Jehovah's Witness patient.  

PubMed

Pulmonary artery aneurysm is a rarely reported and poorly studied entity; most mentions in the literature are in case series and case reports. Cardiac surgery in Jehovah's Witness patients is occurring more frequently because of improved techniques of blood conservation. We report the repair of a large pulmonary artery aneurysm in a 71-year-old woman who was a Jehovah's Witness. Using total cardiopulmonary bypass, we replaced the main pulmonary artery and both branches with Gelweave tube-grafts, because the fragility of a homograft presented possible bleeding problems. The patient recovered rapidly, and her symptoms were greatly improved. We think that a patient's status as a Jehovah's Witness need not preclude potentially life-saving cardiac operations. PMID:23914038

Henn, Lucas W; Esmailian, Fardad

2013-01-01

90

[Acute cholestatic hepatitis caused by simvastatine in a 67-year-old patient].  

PubMed

The following work presents the case of undesired during side effect (toxic hepatocellular damage ) by Simvastatine (Cardin). The main syptoms were jaundice and pruritus. Conclusions draw the attention to the role of history taking in the diagnosis of the described disease, as well as the importance of regular patient checkups whoin those use statines. PMID:17806197

Lata, Stanis?aw; Chudy, Barbara

2006-01-01

91

Perinatal Exposure to a High-Fat Diet Is Associated with Reduced Hepatic Sympathetic Innervation in One-Year Old Male Japanese Macaques  

PubMed Central

Our group recently demonstrated that maternal high-fat diet (HFD) consumption is associated with non-alcoholic fatty liver disease, increased apoptosis, and changes in gluconeogenic gene expression and chromatin structure in fetal nonhuman primate (NHP) liver. However, little is known about the long-term effects that a HFD has on hepatic nervous system development in offspring, a system that plays an important role in regulating hepatic metabolism. Utilizing immunohistochemistry and Real-Time PCR, we quantified sympathetic nerve fiber density, apoptosis, inflammation, and other autonomic components in the livers of fetal and one-year old Japanese macaques chronically exposed to a HFD. We found that HFD exposure in-utero and throughout the postnatal period (HFD/HFD), when compared to animals receiving a CTR diet for the same developmental period (CTR/CTR), is associated with a 1.7 fold decrease in periportal sympathetic innervation, a 5 fold decrease in parenchymal sympathetic innervation, and a 2.5 fold increase in hepatic apoptosis in the livers of one-year old male animals. Additionally, we observed an increase in hepatic inflammation and a decrease in a key component of the cholinergic anti-inflammatory pathway in one-year old HFD/HFD offspring. Taken together, these findings reinforce the impact that continuous exposure to a HFD has in the development of long-term hepatic pathologies in offspring and highlights a potential neuroanatomical basis for hepatic metabolic dysfunction. PMID:23118937

Grant, Wilmon F.; Nicol, Lindsey E.; Thorn, Stephanie R.; Grove, Kevin L.; Friedman, Jacob E.; Marks, Daniel L.

2012-01-01

92

[Severe lower gastrointestinal bleeding in a 25-year-old patient].  

PubMed

Lower gastrointestinal bleeding refers to blood loss originating from a site distal to the ligament of Treitz. The aetiology varies depending on the age of patients. Excluding benign anorectal pathology in children and young people, Meckel's diverticulum, juvenile polyps and inflammatory bowel disease are the main causes. Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract, being present in about 2% of the general population. Most Meckel's diverticulum are asymptomatic and are diagnosed incidentally. The risk of complications is 4-6%, with bleeding as one of them. PMID:23296238

Ruiz Clavijo, D; Fernández-Urién, I; Vila, J J; Goñi, S; González de la Higuera, B; Martínez Echeverría, A

2012-01-01

93

Pyogenic granuloma of unusual size with alveolar resorption in a 75-year-old patient  

PubMed Central

Pyogenic granuloma is an overzealously proliferative non-neoplastic lesion of connective tissue origin, found commonly in oral cavity and is secondary to chronic low grade local irritation, poor oral hygiene, and hormonal disturbances. The term is misnomer because a lesion is unrelated to infection. It is characterized by excessive and exuberant tissue repair response with varied inflammatory component. Since it is a benign lesion, choice of treatment is surgical excision with removal of underlying cause if any. This article aims at presenting a case of pyogenic granuloma in an extremely old patient which is unusual as it attained a very large size and also has caused mild resorption of underlying alveolar bone of mandible. PMID:23251065

Shaikh, Shoyeb; Singh, Gaurav; Singh, Anil; Gaur, Amit

2012-01-01

94

Analysis of the molecular and clinicopathologic features of surgically resected lung adenocarcinoma in patients under 40 years old  

PubMed Central

Introduction The youthful lung cancer may constitute an entity with distinct clinicopathologic characteristics and a controversial prognosis compared with the older counterpart. Whether the youthful lung cancer has the exclusively distinct molecular features has not been well investigated. Methods Thirty-six resected lung adenocarcinomas from young patients under 40 years old were analyzed concurrently for mutations in EGFR, KRAS, HER2, BRAF, AKT1, ALK, RET, TP53 and LKB1 and enrolled as the younger group. Their molecular and clinicopathologic characteristics were compared with those of 87 adenocarcinoma cases from patients above 40 years old which were collected as the older group. Results The comparable overall survival (OS) (P=0.942), more early adenocarcinomas (P=0.033), more wedge resections (P<0.001) and fewer smokers (P=0.004) were seen in the younger group, when compared with the clinicopathologic characteristics in the older group. Nineteen EGFR mutations (52.8%), 3 KRAS mutations (8.3%), 2 EML4-ALK fusions (5.6%) and 1 KIF5b-RET fusion (2.8%) were identified in the younger group. The difference of oncogenic mutations between the two groups was statistically insignificant (P=0.396). Twenty-six TP53 mutations (72.2%) and 4 LKB1 mutations (11.1%) were found in the younger group. When compared with the old patients, young patients showed a higher prevalence of TP53 mutations (P<0.001) and a comparable prevalence of LKB1 mutations (P=0.951). Conclusions The youthful lung cancer unequivocally presented the distinct clinicopathologic characteristics including more early adenocarcinomas and fewer smokers. It showed the similar oncogenic characteristics and higher prevalence of TP53 mutations compared with the older counterpart. PMID:25364516

Ye, Ting; Pan, Yunjian; Wang, Rui; Hu, Haichuan; Zhang, Yang; Li, Hang; Wang, Lei

2014-01-01

95

The Association of Irritability and Impulsivity with Suicidal Ideation Among 15- to 20-Year-Old Males  

ERIC Educational Resources Information Center

Information on the association of impulsivity and measures of aggression with suicidal ideation in adolescents and young adults is limited. Data were gathered from a community sample of 625 adolescent and young adult males. Analyses were based on multivariate generalized estimating equations. Impulsivity and irritability were associated strongly…

Conner, Kenneth R.; Meldrum, Sean; Wieczorek, William F.; Duberstein, Paul R.; Welte, John W.

2004-01-01

96

A 16YearOld Male with Noonan’s Syndrome Develops Progressive Scoliosis and Deteriorating Gait  

Microsoft Academic Search

Robin Bowman, MD: This is a male aged 16½ years, with a complex past medical history involving multiple diagnoses, who was admitted for work-up after presenting with decreased muscle function in his lower extremities, requiring assistance to walk, and decreased endurance with dyspnea. He was born at full term via a normal vaginal delivery. He is a second twin of

Robert A. Sanford; Robin Bowman; Tadanori Tomita; Guillermo De Leon; Peter Palka

1999-01-01

97

Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator for Ischemic Stroke Patients over 80 Years Old: The Fukuoka Stroke Registry  

PubMed Central

Objectives The benefit of intravenous recombinant tissue plasminogen activator (rt-PA) therapy for very old patients with acute ischemic stroke remains unclear. The aim of this study was to elucidate the efficacy and safety of intravenous rt-PA therapy for patients over 80 years old. Methods Of 13,521 stroke patients registered in the Fukuoka Stroke Registry in Japan from June 1999 to February 2013, 953 ischemic stroke patients who were over 80 years old, hospitalized within 3 h of onset, and not treated with endovascular therapy were included in this study. Among them, 153 patients were treated with intravenous rt-PA (0.6 mg/kg). For propensity score (PS)-matched case-control analysis, 148 patients treated with rt-PA and 148 PS-matched patients without rt-PA therapy were selected by 1?1 matching with propensity for using rt-PA. Clinical outcomes were neurological improvement, good functional outcome at discharge, in-hospital mortality, and hemorrhagic complications (any intracranial hemorrhage [ICH], symptomatic ICH, and gastrointestinal bleeding). Results In the full cohort of 953 patients, rt-PA use was associated positively with neurological improvement and good functional outcome, and negatively with in-hospital mortality after adjustment for multiple confounding factors. In PS-matched case-control analysis, patients treated with rt-PA were still at lower risk for unfavorable clinical outcomes than non-treated patients (neurological improvement, odds ratio 2.67, 95% confidence interval 1.61–4.40; good functional outcome, odds ratio 2.23, 95% confidence interval 1.16–4.29; in-hospital mortality, odds ratio 0.30, 95% confidence interval 0.13–0.65). There was no significant association between rt-PA use and risk of hemorrhagic complications in the full and PS-matched cohorts. Conclusions Intravenous rt-PA therapy was associated with improved clinical outcomes without significant increase in risk of hemorrhagic complications in very old patients (aged>80 years) with acute ischemic stroke. PMID:25329379

Matsuo, Ryu; Kamouchi, Masahiro; Fukuda, Haruhisa; Hata, Jun; Wakisaka, Yoshinobu; Kuroda, Junya; Ago, Tetsuro; Kitazono, Takanari

2014-01-01

98

Prosthodontic Rehabilitation of Hereditary Ectodermal Dysplasia in an 11-Year-Old Patient with Flexible Denture: A Case Report  

PubMed Central

Hereditary ectodermal dysplasia is a rare group of inherited disorders characterized by aplasia or dysplasia of two or more tissues of ectodermal origin such as hair, nails, teeth, and skin. The dental characteristics of this syndrome include anodontia or hypodontia of the primary and/or permanent teeth, hypoplastic conical teeth, and underdevelopment of the alveolar ridges. The options for a definitive treatment plan include fixed, removable or implant-supported prostheses, singly or in combination. This clinical report describes the prosthetic rehabilitation of an 11-year-old boy with hereditary ectodermal dysplasia. Maxillary flexible removable partial denture and mandibular conventional complete denture were fabricated to establish an acceptable masticatory function, speech, and esthetics for the patient. PMID:23320200

Jain, Neha; Naitam, Dinesh; Wadkar, Arti; Nemane, Anuradha; Katoch, Shiva; Dewangan, Ashish

2012-01-01

99

[Alopecia totalis, hypotension and erectile dysfunction in a 34 year old patient. Difficult clarification of a common cause].  

PubMed

The occurrence of both autoimmune endocrinopathies and endocrinopathies caused by other reasons is called polyglandular autoimmune syndrome (PAS-syndrome). In a 34 years old man with weakness, weight loss and erectile dysfunction we found low cortisol caused by an autoimmune adrenalitis and low testosterone caused by a hypophysitis with impaired gonadotropin secretion. Thyroid autoantibodies and islet cell autoantibodies without any hormone deficiencies were further signs of a broad endocrine autoimmune syndrome. In the following 11 years the patient developed three autoimmune disorders: paradrenal glandular insufficiency, hypogonadism caused by hypophysitis, Diabetes mellitus type 1. In the same time several non endocrine autoimmune diseases became manifest: alopecia totalis, vitiligo, retrobulbar neuritis and keratoconjunctivitis. PMID:15800777

Hunger-Dathe, W; Braun, A; Müller, U A

2005-06-01

100

Management of a 59-year-old female patient with adult degenerative scoliosis using manipulation under anesthesia  

PubMed Central

Objective Manipulation under anesthesia (MUA) is an outpatient procedure that is performed to restore normal joint kinematics and musculoskeletal function. This article presents a case of a patient with idiopathic lumbar degenerative scoliosis who developed intractable pain as an adult and reports on the outcomes following a trial of MUA. Clinical Features A 59-year-old female patient presented to a chiropractic office with primary subjective symptoms of lower back and bilateral hip pain. Numerical pain rating scores were reported at 8 of 10 for the lower back and 9 of 10 for the sacroiliac joint/gluteal region. A disability score using a functional rating index demonstrated a score of 26 of 40 (or 64% disability). Over the preceding 5 years, the patient had tried a number of conservative therapies to relieve her pain without success. Intervention and Outcome The patient was evaluated for MUA. The patient was scheduled for a serial MUA over 3 days. Numerical pain rating scores 8 weeks after the MUA were 1 of 10 for the lower back and 3 of 10 for the sacroiliac joint. Her disability rating decreased to 11 of 40 (28%). Radiological improvements were also observed. These outcomes were maintained at 6-month follow-up. Conclusion Pain, functional, and radiographic outcomes demonstrated improvements immediately following treatment for this patient. PMID:21629554

Morningstar, Mark W.; Strauchman, Megan N.

2010-01-01

101

A 90-year-old patient presenting with postoperative hypotension and a new murmur: a case report  

PubMed Central

Introduction Hospitalists are frequently consulted on postoperative patients with hypotension. Postoperative hypotension is common and can be due to variety of causes. Systolic anterior motion of the mitral valve leading to left ventricular outflow tract obstruction is a rare cause of postoperative hypotension and can occur without prior structural heart disease. A high index of suspicion can lead to early recognition of this unique condition. Case presentation A 90-year-old Caucasian woman with no known structural heart abnormality was admitted to the intensive care unit with hypotension after a left hip arthroplasty revision. A transthoracic echocardiogram revealed systolic anterior motion of the mitral valve and dynamic left ventricular outflow tract obstruction as the likely cause of her hypotension. Our patient was treated with fluid resuscitation and phenylephrine with improvement in blood pressure. A repeat echocardiogram on postoperative day 5 showed resolution of the left ventricular outflow tract obstruction. Intraoperative vasodilatation and volume loss that caused underfilling of the left ventricle likely led to dynamic outflow tract obstruction in our patient. Conclusions Hospitalists should be aware of systolic anterior motion of the mitral valve as a rare peri-operative complication in patients with or without underlying cardiac pathology as it is treated differently than other causes of peri-operative hypotension. Clinical suspicion, early recognition, and prompt treatment can improve clinical outcomes in these patients. PMID:25384414

2014-01-01

102

Curing a 96-year-old patient afflicted with benign paroxysmal positional vertigo on a motorized turntable  

PubMed Central

Background Dizziness in the elderly is a serious health concern due to the increased morbidity caused by falling. The most common cause of dizziness in the elderly, benign paroxysmal positional vertigo (BPPV), is frequently undiagnosed, and bedside treatment of these patients can be difficult due to neck and back stiffness, which makes repeated and accurate repositioning maneuvers difficult. Case presentation After a fall, a 96-year-old woman was referred by a resident neurologist for intractable BPPV. The patient was placed on a motorized turntable and repositioned to remove the calcite particles from the affected posterior semicircular canal. Video monitoring of the eyes allowed confirmation of the diagnosis, as well as an immediate evaluation of the effectiveness of the maneuver. Conclusion Every patient with dizziness or imbalance, even in the absence of typical complaints of BPPV, should be tested with provocation maneuvers, because the clinical picture of BPPV is not always typical. Even if elderly patients with dizziness are very frail, the completion of provocation maneuvers is imperative, since the therapeutic maneuvers are extremely effective. A motorized turntable is very helpful to perform the repositioning accurately and safely. PMID:24748776

Bockisch, Christopher J; Straumann, Dominik; Weber, Konrad P

2014-01-01

103

Quantification of biological tissue and construction of patient equivalent phantom (skull and chest) for infants (1-5 years old)  

NASA Astrophysics Data System (ADS)

Our main purpose in this study was to quantify biological tissue in computed tomography (CT) examinations with the aim of developing a skull and a chest patient equivalent phantom (PEP), both specific to infants, aged between 1 and 5 years old. This type of phantom is widely used in the development of optimization procedures for radiographic techniques, especially in computed radiography (CR) systems. In order to classify and quantify the biological tissue, we used a computational algorithm developed in Matlab ®. The algorithm performed a histogram of each CT slice followed by a Gaussian fitting of each tissue type. The algorithm determined the mean thickness for the biological tissues (bone, soft, fat, and lung) and also converted them into the corresponding thicknesses of the simulator material (aluminum, PMMA, and air). We retrospectively analyzed 148 CT examinations of infant patients, 56 for skull exams and 92 were for chest. The results provided sufficient data to construct a phantom to simulate the infant chest and skull in the posterior-anterior or anterior-posterior (PA/AP) view. Both patient equivalent phantoms developed in this study can be used to assess physical variables such as noise power spectrum (NPS) and signal to noise ratio (SNR) or perform dosimetric control specific to pediatric protocols.

Alves, A. F.; Pina, D. R.; Bacchim Neto, F. A.; Ribeiro, S. M.; Miranda, J. R. A.

2014-03-01

104

Robot-assisted laparoscopic prostatectomy in a 68-year-old patient with previous heart transplantation and pelvic irradiation  

Microsoft Academic Search

We report the case of a 68-year-old man who had previously undergone heart transplantation and pelvic irradiation for Hodgkin’s\\u000a lymphoma and who was under active surveillance for prostate cancer. In response to his increased prostate-specific antigen\\u000a levels and elevated Gleason score, he was offered robot-assisted laparoscopic prostatectomy.

Karol Axcrona; Ljiljana Vlatkovic; Jarl Hovland; Bjørn Brennhovd; Ulf Kongsgaard; Karl-Erik Giercksky

105

Blinding Bilateral Hyperviscosity Retinopathy in a 43-Year-Old Nigerian Male with Lymphoplasmacytic Lymphoma: A Case Report and Management Challenges  

PubMed Central

Lymphoplasmacytic lymphomas are rare and may present with uncommon and devastating symptoms. We report a case of a 43-year-old male who presented with bleeding gums and sudden onset of bilateral blindness but was not on anticoagulants and had no family history of bleeding disorder. He had bilateral hyperpigmented infraorbital skin lesions, visual acuities (VA) of hand motion in both eyes (blindness), round and sluggish pupils, and bilateral diffuse and extensive retinal haemorrhages obliterating the retinal details with central visual field defects. The optical coherence tomography revealed retinal haemorrhage, oedema, detachment, and diffuse photoreceptors damage. Investigations revealed elevated ESR and ?2 microglobulin, monoclonal peak on serum protein electrophoresis, high IG with lambda restriction on serum, and urine immunofixation with increased lymphocytes and plasma cells in the bone marrow. A diagnosis of lymphoplasmacytic lymphoma complicated by blinding hyperviscosity retinopathy was made. In the absence of an aphaeresis machine, he received four cycles of manual exchange blood transfusion (EBT) and commenced with chlorambucil/prednisolone due to difficulty in obtaining blood for continued EBT. His general condition and VA has improved and he is stable for more than six months into treatment. PMID:24883217

Ayanniyi, Abdulkabir A.; Ejikeme, Uchenna Godswill; Tanko, Yohanna; Muhammad, Rilwan C.; Nnodu, Obiageli E.

2014-01-01

106

Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: Report of a case  

PubMed Central

Background Pulmonary sclerosing hemangioma (SH) is a rare tumor of the lung predominantly affecting Asian women in their fifth decade of life. SH is thought to evolve from primitive respiratory epithelium and mostly shows benign biological behavior; however, cases of lymph node metastases, local recurrence and multiple lesions have been described. Case Presentation We report the case of a 21-year-old Caucasian male with a history of locally advanced and metastatic rectal carcinoma (UICC IV; pT4, pN1, M1(hep)) that was eventually identified as having hereditary non-polyposis colorectal cancer (HNPCC, Lynch syndrome). After neoadjuvant chemotherapy followed by low anterior resection, adjuvant chemotherapy and metachronous partial hepatectomy, he was admitted for treatment of newly diagnosed bilateral pulmonary metastases. Thoracic computed tomography showed a homogenous, sharply marked nodule in the left lower lobe. We decided in favor of atypical resection followed by systematic lymphadenectomy. Histopathological analysis revealed the diagnosis of SH. Conclusions Cases have been published with familial adenomatous polyposis (FAP) and simultaneous SH. FAP, Gardner syndrome and Li-Fraumeni syndrome, however, had been ruled out in the present case. To the best of our knowledge, this is the first report describing SH associated with Lynch syndrome. PMID:21645337

2011-01-01

107

Blinding bilateral hyperviscosity retinopathy in a 43-year-old nigerian male with lymphoplasmacytic lymphoma: a case report and management challenges.  

PubMed

Lymphoplasmacytic lymphomas are rare and may present with uncommon and devastating symptoms. We report a case of a 43-year-old male who presented with bleeding gums and sudden onset of bilateral blindness but was not on anticoagulants and had no family history of bleeding disorder. He had bilateral hyperpigmented infraorbital skin lesions, visual acuities (VA) of hand motion in both eyes (blindness), round and sluggish pupils, and bilateral diffuse and extensive retinal haemorrhages obliterating the retinal details with central visual field defects. The optical coherence tomography revealed retinal haemorrhage, oedema, detachment, and diffuse photoreceptors damage. Investigations revealed elevated ESR and ? 2 microglobulin, monoclonal peak on serum protein electrophoresis, high IG with lambda restriction on serum, and urine immunofixation with increased lymphocytes and plasma cells in the bone marrow. A diagnosis of lymphoplasmacytic lymphoma complicated by blinding hyperviscosity retinopathy was made. In the absence of an aphaeresis machine, he received four cycles of manual exchange blood transfusion (EBT) and commenced with chlorambucil/prednisolone due to difficulty in obtaining blood for continued EBT. His general condition and VA has improved and he is stable for more than six months into treatment. PMID:24883217

Ayanniyi, Abdulkabir A; Ejikeme, Uchenna Godswill; Tanko, Yohanna; Muhammad, Rilwan C; Nnodu, Obiageli E

2014-01-01

108

Shiga Toxin-Producing Escherichia coli-Associated Kidney Failure in a 40YearOld Patient and Late Diagnosis by Novel Bacteriologic and Toxin Detection Methods  

Microsoft Academic Search

CASE REPORT A 40-year-old African-American male with a 10-year history of hypertension presented at a community hospital with several days of abdominal cramps, vomiting, and loose stool with in- terspersed blood. Upon admission, he was found to be in acute renal failure with anemia and occult blood in the stool. He was afebrile, with an elevated blood pressure of 243

Louise D. Teel; Brett R. Steinberg; Naomi E. Aronson; Alison D. O'Brien

2003-01-01

109

Bilateral Optic Nerve Sheath Meningioma with Intracanalicular and Intracranial Component in a 25-year-old Saudi Patient  

PubMed Central

Bilateral optic nerve sheath meningioma is rare. A meningioma is a benign neoplastic lesion from meningothelial cells of the meninges. They usually involve the intracanalicular portion of the optic nerve but may extend into the optic canal and through it to occupy the intracranial space. We present a case of 25-year-old Saudi female with bilateral optic nerve sheath meningioma. The diagnosis was delayed more than six years from initial symptoms. PMID:21369471

Badr, Maha A.; Elkhamary, Sahar M.; Al Sabbagh, Samira; Al Turjoman, Abdulsalam

2008-01-01

110

Effect of Postmastectomy Radiotherapy in Patients <35 Years Old With Stage II-III Breast Cancer Treated With Doxorubicin-Based Neoadjuvant Chemotherapy and Mastectomy  

SciTech Connect

Purpose: Postmastectomy radiotherapy (PMRT) improves locoregional control (LRC) in patients with high-risk features after mastectomy. Young age continues to evolve as a potentially important risk factor. The objective of this study was to assess the benefits of PMRT in patients <35 years old treated with doxorubicin-based neoadjuvant chemotherapy for Stage II-III breast cancer. Patients and Methods: We retrospectively analyzed 107 consecutive breast cancer patients <35 years old with Stage IIA-IIIC disease treated at our institution with doxorubicin-based neoadjuvant chemotherapy and mastectomy, with or without PMRT. The treatment groups were compared in terms of LRC and overall survival. Results: Despite more advanced disease stages, the patients who received PMRT (n = 80) had greater rates of LRC (5-year rate, 88% vs. 63%, p = 0.001) and better overall survival (5-year rate, 67% vs. 48%, p = 0.03) than patients who did not receive PMRT (n = 27). Conclusion: Among breast cancer patients <35 years old at diagnosis, the use of PMRT after doxorubicin-based neoadjuvant chemotherapy and mastectomy led to a statistically greater rate of LRC and overall survival compared with patients without PMRT. The benefit seen for PMRT in young patients provides valuable data to better tailor adjuvant, age-specific treatment decisions after mastectomy.

Garg, Amit K. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Oh, Julia L. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)], E-mail: joh@mdanderson.org; Oswald, Mary Jane; Huang, Eugene; Strom, Eric A.; Perkins, George H.; Woodward, Wendy A.; Yu, T. Kuan; Tereffe, Welela [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Meric-Bernstam, Funda [Department of Surgical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Hahn, Karin [Department of Breast Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Buchholz, Thomas A. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)

2007-12-01

111

Non-Contrast-Enhanced Whole-Body Magnetic Resonance Imaging in the General Population: The Incidence of Abnormal Findings in Patients 50 Years Old and Younger Compared to Older Subjects  

PubMed Central

Purpose To assess and compare the incidence of abnormal findings detected during non-contrast-enhanced whole-body magnetic resonance imaging (WB-MRI) in the general population in two age groups: (1) 50 years old and younger; and (2) over 50 years old. Materials and Methods The analysis included 666 non-contrast-enhanced WB-MRIs performed on a 1.5-T scanner between December 2009 and June 2013 in a private hospital in 451 patients 50 years old and younger and 215 patients over 50 years old. The following images were obtained: T2-STIR (whole body-coronal plane), T2-STIR (whole spine-sagittal), T2-TSE with fat-saturation (neck and trunk-axial), T2-FLAIR (head-axial), 3D T1-GRE (thorax-coronal, axial), T2-TSE (abdomen-axial), chemical shift (abdomen-axial). Detected abnormalities were classified as: insignificant (type I), potentially significant, requiring medical attention (type II), significant, requiring treatment (type III). Results There were 3375 incidental findings depicted in 659 (98.9%) subjects: 2997 type I lesions (88.8%), 363 type II lesions (10.8%) and 15 type III lesions (0.4%), including malignant or possibly malignant lesions in seven subjects. The most differences in the prevalence of abnormalities on WB-MRI between patients 50 years old and younger and over 50 years old concerned: brain infarction (22.2%, 45.0% respectively), thyroid cysts/nodules (8.7%, 18.8%), pulmonary nodules (5.0%, 16.2%), significant degenerative disease of the spine (23.3%, 44.5%), extra-spinal degenerative disease (22.4%, 61.1%), hepatic steatosis (15.8%, 24.9%), liver cysts/hemangiomas (24%, 34.5%), renal cysts (16.9%, 40.6%), prostate enlargement (5.1% of males, 34.2% of males), uterine fibroids (16.3% of females, 37.9% of females). Conclusions Incidental findings were detected in almost all of the subjects. WB-MRI demonstrated that the prevalence of the vast majority of abnormalities increases with age. PMID:25259581

Cieszanowski, Andrzej; Maj, Edyta; Kulisiewicz, Piotr; Grudzinski, Ireneusz P.; Jakoniuk-Glodala, Karolina; Chlipala-Nitek, Irena; Kaczynski, Bartosz; Rowinski, Olgierd

2014-01-01

112

Minoxidil induced hypertrichosis in a 2 year-old child.  

PubMed

We report a case of a 2 year-old male patient who developed generalized hypertrichosis after 2 months of treatment with 5% minoxidil foam for alopecia areata. This report highlights the danger of prescribing  topical minoxidil to young children and the need to correctly instruct caretakers about its administration. PMID:24555107

Herskovitz, Ingrid; Freedman, Joshua; Tosti, Antonella

2013-01-01

113

Minoxidil induced hypertrichosis in a 2 year-old child  

PubMed Central

We report a case of a 2 year-old male patient who developed generalized hypertrichosis after 2 months of treatment with 5% minoxidil foam for alopecia areata. This report highlights the danger of prescribing  topical minoxidil to young children and the need to correctly instruct caretakers about its administration. PMID:24555107

Herskovitz, Ingrid

2013-01-01

114

Limited Impact on Health and Access to Care for 19- to 25-Year-Olds Following the Patient Protection and Affordable Care Act  

PubMed Central

IMPORTANCE The Patient Protection and Affordable Care Act (PPACA) allowed young adults to remain on their parents’ insurance until 26 years of age. Reports indicate that this has expanded health coverage. OBJECTIVE To evaluate coverage, access to care, and health care use among 19- to 25-year-olds compared with 26- to 34-year-olds following PPACA implementation. DESIGN, SETTING, AND PARTICIPANTS Data from the Behavior Risk Factor Surveillance System and the National Health Interview Survey, which provide nationally representative measures of coverage, access to care, and health care use, were used to conduct the study among participants aged 19 to 25 years (young adults) and 26 to 34 years (adults) in 2009 and 2012. EXPOSURE Self-reported health insurance coverage. MAIN OUTCOMES AND MEASURES Health status, presence of a usual source of care, and ability to afford medications, dental care, or physician visits. RESULTS Health coverage increased between 2009 and 2012 for 19- to 25-year-olds (68.3% to 71.7%). Using a difference-in-differences (DID) approach, after adjustment, the likelihood of having a usual source of care decreased in both groups but more significantly for 26- to 34-year-olds (DID, 2.8%; 95% CI, 0.45 to 5.15). There was no significant change in health status for 19- to 25-year-olds compared with 26- to 34-year-olds (DID, ?0.5%; 95% CI, ?1.87 to 0.87). There was no significant change for 19- to 25-year-olds compared with 26- to 34-year-olds in the percentage who reported receiving a routine checkup in the past year (DID, 0.3%; 95% CI, ?2.25 to 2.85) or in the ability to afford prescription medications (DID, ?0.4%; 95% CI, ?2.93 to 1.93), dental care (DID, ?2.6%; 95% CI, ?5.61 to 0.61), or physician visits (DID, ?1.7%; 95% CI, ?3.66 to 0.26). There was also no change in the percentage who reported receiving a flu shot (DID, 1.9; 95% CI, ?1.93 to 4.93). Insured individuals were more likely to report having a usual source of care and a recent routine checkup and were more likely to be able to afford health care than uninsured individuals. CONCLUSIONS AND RELEVANCE Implementation of the PPACA was associated with increased health insurance coverage for 19- to 25-year-olds without significant changes in perceived health care affordability or health status. Although the likelihood of having a usual source of care declined between 2009 and 2012 for all, this decrease was smaller among 19- to 25-year-olds, and younger adults were more likely than 26- to 34-year-olds to have a usual source of care. PMID:25200181

Kotagal, Meera; Carle, Adam C.; Kessler, Larry G.; Flum, David R.

2014-01-01

115

Myopathy in a 20-year-old female patient with D4ST-1 deficient Ehlers-Danlos syndrome due to a homozygous CHST14 mutation.  

PubMed

We here report on a 20-year-old female patient with EDS due to a homozygous CHST14 single nucleotide deletion resulting in D4ST-1 deficiency, accompanied by muscle hypoplasia and muscle weakness. Findings of muscle ultrasound, electromyography, and muscle biopsy pointed to a myopathy, similarly as in other EDS types. This myopathy probably contributes to the gross motor developmental delay in this type of EDS. PMID:22407744

Voermans, N C; Kempers, M; Lammens, M; van Alfen, N; Janssen, M C; Bönnemann, C; van Engelen, B G; Hamel, B C

2012-04-01

116

A 5YearOld Boy with Cryptorchidism and Pubic Hair: Investigation and Management of Apparent Male Disorders of Sex Development in Mid-Childhood  

Microsoft Academic Search

Background: Late presentation of congenital adrenal hyperplasia as a 46,XX disorder of sex development due to 11-? hydroxylase deficiency is uncommon. Such a case raises issues regarding appropriate investigation and management. Case History: A 5-year-old boy who had recently moved to the United Kingdom presented at the endocrinology clinic with recurrent abdominal pain. He was normotensive and had a history

L. S. Keir; S. O’Toole; A. L. Robertson; A. M. Wallace; S. F. Ahmed

2009-01-01

117

Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old  

PubMed Central

Background In clinical practice, unexpected diagnosis of colorectal cancer in young patients requires prompt surgery, thus genetic testing for Lynch Syndrome is frequently missed, and clinical management may result incorrect. Methods Patients younger than 50 years old undergoing colorectal resection for cancer in the period 1994-2007 were identified (Group A, 49 cases), and compared to a group of randomly selected patients more than 50 (Group B, 85 cases). In 31 group A patients, immunohistochemical expression analysis of MLH1, MSH2 and MSH6 was performed; personal and familial history of patients with defective MMR proteins expression was further investigated, searching for synchronous and metachronous tumors in probands and their families. Results Fifty-one percent of patients did not express one or more MMR proteins (MMR-) and should be considered Lynch Syndrome carriers (16 patients, group A1); while only 31.2% of them were positive for Amsterdam criteria, 50% had almost another tumor, 37.5% had another colorectal tumor and 68% had relatives with colorectal tumor. This group of patients, compared with A2 group (< 50 years old, MMR+) and B group, showed typical characteristics of HNPCC, such as proximal location, mucinous histotype, poor differentiation, high stage and shorter survival. Conclusions The present study confirms that preoperative knowledge of MMR proteins expression in colorectal cancer patients would allow correct staging, more extended colonic resection, specific follow-up and familial screening. PMID:24533633

2014-01-01

118

Central low-grade osteosarcoma with an unusual localization in the diaphysis of a 12-year old patient  

PubMed Central

Background Low-grade central osteosarcoma is a very rare subtype of osteosarcoma with a predilection for the metaphysis of long bones and a peak incidence in the 3rd decade of life. Absence of specific clinical symptoms and a good prognosis after wide resection are the characteristics of this entity. Chemotherapy is not indicated in this highly differentiated tumour. Case report A 12-year old girl presented with limping, swelling and pain in the mid of the left femur. Radiography showed a 12 cm long intraosseous expansion with lamellated periosteal reaction and contrast medium enhancement in MRI. Although radiology led to the differential diagnoses of Ewing’s sarcoma, osteomyelitis and fibrous dysplasia, the histological specimen showed a hyopocellular spindle-cell proliferation arranged in fascicles with mild cytologic atypia and only single mitotic figures. In synopsis with radiology the diagnosis of low-grade central osteosarcoma was made and confirmed by reference pathology. The tumour was resected with wide margins and reconstruction was performed with a vascularized fibula, a homologous allograft and a plate. Staging was negative for recurrence and metastasis at a follow-up of 16 months. Conclusions Low-grade osteosarcoma accounts for only 1% of all osteosarcomas with a peak incidence in the 3rd decade. The diaphyseal localization and the young age make this case special. To achieve the correct diagnosis of this rare low-grade entity and thereby the adequate treatment, despite a wide range of differential diagnoses, a multidisciplinary approach is essential. PMID:23801917

Gilg, Magdalena Maria; Liegl, Bernadette; Wibmer, Christine; Maurer-Ertl, Werner; Leithner, Andreas

2013-01-01

119

Blood parameters of one-year-old and seven-year old partridges (Alectoris chukar).  

PubMed

Several blood parameters were determined for 12 1-year-old and 12 7-year-old partridges to establish base line values on blood chemistry of this species. After taking blood samples, the 7-year-old birds were killed and necropsied for gross examination. With aging, there was a significant increase in plasma glucose, glutamic-oxalacetic transaminase (GOT), potassium, cholesterol, uric acid, and albumin. Males generally had a significantly lower lactic dehydrogenase (LDH) than females. The 7-year-old males had a significantly higher plasma cholesterol and GOT than 1-year-old males. There were no differences in plasma potassium, sodium, and calcium between partridges and data previously reported for chickens. Blood glucose levels in young and old partridge appear to be twice that for chickens, whereas cholesterol and lactic dehydrogenase levels were much lower in chickens. PMID:6669515

Woodard, A E; Vohra, P; Mayeda, B

1983-12-01

120

Emotional Development: 1 Year Olds  

MedlinePLUS

... 1 Year Olds Ages & Stages Listen Emotional Development: 1 Year Olds Article Body Throughout her second year, ... for shelter. She may seem to change from one moment to the next, or she may seem ...

121

Anesthetic management of hypertensive crisis in a three-year-old patient with undiagnosed severe renal artery stenosis: a case report  

PubMed Central

Pediatric hypertensive crisis is a potentially life threatening medical emergency, usually secondary to an underlying disease. Hypertension commonly occurs during general anesthesia, and is usually promptly and appropriately treated by anesthesiologists. However in children with severe, unexplained, or refractory hypertension, it has the potential to cause morbidity and even mortality in susceptible patients. We report an anesthetic management of an unexpected hypertensive crisis that developed during general anesthesia in a three-year-old girl with undiagnosed severe left renal artery stenosis. PMID:25368787

Park, Sang-hee; Min, Too Jae; Kim, Woon Young; Kim, Jae Hwan; Park, Young Cheol

2014-01-01

122

Multimodal endovascular management of acute ischemic stroke in patients over 75 years old is safe and effective  

PubMed Central

Introduction Greater attention has been directed to endovascular recanalization of acute ischemic stroke in septuagenarians and above. Technique A retrospective chart review was conducted to include patients treated for acute ischemic stroke from 2006 to 2012. All patients underwent initial neurological assessment and non-contrast head CT. Patients treated from 2009 to 2012 additionally received emergent CT angiogram and CT perfusion. 51 patients met the clinical and radiographic criteria and underwent multimodal endovascular revascularization for acute ischemic events. Results All patients underwent cerebral angiography and met angiographic criteria for endovascular thrombolysis. 34 patients (67%) were older than 80?years of age. 23 patients (45%) received intravenous tissue plasminogen activator prior to admission. Eight (16%) patients underwent stent placement after intra-arterial thrombolysis, 10 (20%) underwent balloon angioplasty and seven (14%) underwent both angioplasty and stent placement. 21 (41%) required only intra-arterial thrombolytics. An improvement in Thrombolysis in Myocardial Infarction score was noted in 34 patients (67%). The average modified Rankin Scale score on discharge was 3.9. Symptomatic intracranial hemorrhage occurred in three patients (6%); none required surgery. One patient (1.9%) had a postoperative retroperitoneal hematoma, which was managed conservatively. Two fatalities resulted from intraoperative vessel rupture (3.9%), with a combined morbidity and mortality of 27.5%. Conclusions Multimodal endovascular recanalization of acute ischemic stroke is a relatively safe treatment option in patients older than 75?years of age. Careful patient selection by clinical and radiographic inclusion criteria is necessary for the successful management of stroke in this age group. PMID:22791182

Ghobrial, George M; Chalouhi, Nohra; Rivers, Lana; Witte, Samantha; Davanzo, Justin; Dalyai, Richard; Gardecki, Michelle L; Jabbour, Pascal; Gonzalez, Fernando; Dumont, Aaron S; Rosenwasser, Robert H; Tjoumakaris, Stavropoula

2013-01-01

123

Perioperative risk factors affecting hospital stay and hospital costs in open heart surgery for patients) 65 years old1  

Microsoft Academic Search

Objective: Demographic changes, associated with increased demands for open heart surgery in the elderly, place increased burden on financial resources. To evaluate perioperative risk factors affecting incidence of hospital events and estimation of hospital charges, 2577 patients)65 years (range 65-91), operated on from January 1991 to December 1994, were compared with a concurrent cohort of 2642 younger patients. Methods: Statistical

Javier Fernandez; Chao Chen; Gail Anolik; Otto B. Brdlik; Glenn W. Laub; William A. Anderson; Lynn B. McGrath

124

Eruptive Nevi Mimicking Wart-Like Lesions under Selective BRAF Inhibition in a 37-Year-Old Female Melanoma Patient  

PubMed Central

Background The BRAF inhibitor vemurafenib is state of the art in therapy of patients with malignant melanoma in non-resectable stage III or stage IV and evidence of oncogenetic BRAF mutation. Multiple cutaneous side effects like rash and keratoacanthoma-like lesions have been described so far. Case Report We report a patient who presented multiple wart-like lesions under therapy with vemurafenib. Histologically we have seen multiple melanocytic nevi with a wart-like appearance. One melanoma in situ developed on the left forearm. Conclusions Eruptive nevi and induction of melanoma may be a further side effect in patients undergoing a therapy with BRAF inhibitors. PMID:23626542

Schmitt, Laurenz; Schumann, Tamara; Inhoff, Oliver; Loser, Christoph; Rebel, Martin; Dippel, Edgar

2013-01-01

125

Outcome Following Decompressive Craniectomy for Malignant Middle Cerebral Artery Infarction in Patients Older Than 70 Years Old  

PubMed Central

Objective Malignant middle cerebral artery (MCA) infarction occurs in 10% of all ischemic strokes and these severe strokes are associated with high mortality rates. Recent clinical trials demonstrated that early decompressive craniectomy reduce mortality rates and improves functional outcomes in healthy young patients (less than 61 years of age) with a malignant infarction. The purpose of this study was to assess the efficacy of decompressive craniectomy in elderly patients (older than 70 years of age) with a malignant MCA infarction. Methods Between February 2008 and October 2011, 131 patients were diagnosed with malignant MCA infarctions. We divided these patients into two groups: patients who underwent decompressive craniectomy (n = 58) and those who underwent conservative care (n = 73). A cut-off point of 70 years of age was set, and the study population was segregated into those who fell above or below this point. Mortality rates and functional outcome scores were assessed, and a modified Rankin Scale (mRS) score of > 3 was considered to represent a poor outcome. Results Mortality rates were significantly lower at 29.3% (one-month mortality rate) and 48.3% (six-month mortality rate) in the craniectomy group as compared to 58.9% and 71.2%, respectively, in the conservative care group (p < 0.001, p = 0.007). Age (?70 years vs. < 70 years) did not statistically differ between groups for the six-month mortality rate (p = 0.137). However, the pre-operative National Institutes of Health Stroke Scale (NIHSS) score did contribute to the six-month mortality rate (p = 0.047). Conclusion Decompressive craniectomy is effective for patients with a malignant MCA infarction regardless of their age. Therefore, factors other than age should be considered and the treatment should be individualized in elderly patients with malignant infarctions. PMID:23210030

Yu, Jae Won; Choi, Jae-Hyung; Kim, Dae-Hyun; Cha, Jae-Kwan

2012-01-01

126

[Serious course of a miliary tuberculosis in a 34-year-old patient with ulcerative colitis and HIV infection under concomitant therapy with infliximab].  

PubMed

A 34-year-old HIV-positive patient with ulcerative colitis was transferred to the authors' hospital because of progressive worsening of his general condition with intermittent fever, increasing lymphopenia, anemia, thrombopenia and neutropenia under anti-tumor necrosis factor-(TNF-)alpha therapy with infliximab. In spite of negative screening tests before initiation of infliximab therapy and intermittent tests during treatment, miliary tuberculosis was finally diagnosed and a tuberculostatic therapy was started. The patient's clinical condition worsened due to the development of a serious exudative necrotizing pancreatitis which was likely to be caused by the tuberculostatic treatment. Due to severe pulmonary infiltrates and pleural effusions with respiratory failure the patient finally passed away. PMID:20455057

Zeitz, Jonas; Huber, Milo; Rogler, Gerhard

2010-04-01

127

FH Tulsa-1 and -2: Two unique alleles for familial hypercholesterolemia presenting in an affected two-year-old African-American male  

SciTech Connect

A two-year-old African American boy presented with cutaneous xanthomata and extreme hypercholesterolemia. Subsequent studies revealed that the LDL-cholesterol was 1,001 mg/dl and apoB 507 mg/dl. LDL-receptor activity was almost undetectable, which is compatible with the finding of two newly described defective alleles on exon 4 of the LDL-receptor gene coding for part of the ligand-binding domain. One allele contained a 21 base-pair insertion from codon 200 to 207 whereas the other had a point mutation at codon 207. The rarity of genes for FH reported in individuals of African ancestry is discussed. 16 refs., 2 figs., 2 tabs.

Blackett, P.R.; Altmiller, D.H. [Univ. of Oklahoma Health Services Center, Oklahoma City, OK (United States); Jelley, D. [Childrens Medical Center, Tulsa, OK (United States); Wilson, D.P. [Driscoll Children`s Hospital, Corpus Christi, TX (United States)

1995-11-20

128

Reinnervation of facial muscles with only a cross-facial nerve graft in a 25-year-old patient with congenital facial palsy.  

PubMed

The standard method for managing chronic facial palsy is the two-stage free-muscle flap. We report a case involving a 25-year-old patient who had facial palsy from her birth. Twelve months after the first stage of a cross-facial nerve graft, we found that the voluntary movements of her facial muscles had returned. Within the following 12 months, she gained complete recovery of her movements on the affected side, as confirmed by electromyography studies. This case demonstrates that neurotization of facial muscles in chronic facial palsy is possible. However, further studies are needed to define the trophic effects or trophic mediators that can restore function to atrophied facial muscles and to determine which patients might benefit from the cross-facial nerve graft procedure without the free-muscle graft procedure. PMID:25025423

Seyed-Forootan, Kamal; Karimi, Hamid; Hasani, Esmaiil

2014-07-01

129

A 12-year-old student athlete with exercise-induced bronchospasm: Getting Jenny B. back on track: A case 360 degrees patient presentation.  

PubMed

Jenny B. is an active 12-year-old white female who recently stopped participating in junior high school track because of respiratory symptoms she experiences while running. On presentation to her pediatrician's office for a consultation, it immediately became apparent that she was anxious to rejoin her team to compete. This article will navigate through a patient case and explore multiple clinical approaches to exercise-induced broncho-spasm from diagnosis to treatment. As clinicians, our goal is to partner with all patients who experience asthma or respiratory symptoms, enabling them to have a life without limitations. Let us review Jenny B.'s case and examine what might be the best approach to get her back on track. PMID:19781513

Mosnaim, Giselle

2009-01-01

130

Language Development: 2 Year Olds  

MedlinePLUS

... Ages & Stages > Toddler > Language Development: 2 Year Olds Ages & Stages Listen Language Development: 2 Year Olds Article Body Your two- ... school. You can help enrich his vocabulary and language skills by making reading a part of your everyday routine. At this age, he can follow a story line and will ...

131

Free flap scalp reconstruction in a 91-year-old patient under local-regional anesthesia: case report and review of the literature.  

PubMed

In the elderly population with significant medical comorbidities, the safety of general anesthesia is often in question. In the head and neck, where regional and extradural anesthesia are not options, reconstruction of defects requiring free tissue transfer becomes a particular challenge for patients in whom general anesthesia is contraindicated. We present a case of a scalp reconstruction utilizing a latissimus dorsi free flap in a 91-year-old man performed entirely under local and regional anesthesia. General anesthesia was contraindicated secondary to the patient's multiple medical comorbidities. A paravertebral block was used for the harvest of the latissimus dorsi muscle and skin grafts. The microvascular portion of the procedure and the inset were performed under local anesthesia alone. The patient tolerated the procedure, and the operation was successful. This case is unique in that there are no published reports of head and neck free tissue transfer being performed entirely under local-regional anesthesia. We conclude that despite the medical challenges of performing complex reconstruction in elderly patients, expedient free tissue transfer can offer patients access to successful reconstruction. PMID:22274769

Carey, Joseph Nicholas; Watt, Andrew J; Ho, Oscar; Zeidler, Kamakshi; Lee, Gordon Kwanlyp

2012-03-01

132

[A case of a 91-year-old patient with advanced squamous cell lung cancer complicated with renal dysfunction successfully treated with trans-arterial chemo-embolization].  

PubMed

In 2009, a 91-year-old man with renal dysfunction was detected with a small nodule in the left pulmonary field. The nodule was found to have gradually increased in size by April, 2010. A trans-bronchial lung biopsy(TBLB)and computed tomography( CT)revealed squamous cell lung cancer and stage IV (a tumor was found on the right side as well), respectively. Systemic chemotherapy was not administered because of the advanced age of the patient and mild renal dysfunction. We obtained informed consent from the patient and his family before trans-arterial chemo-embolization(TACE)was performed. No side effects were observed either during or after treatment. Although his visits to our hospital stopped, he sought treatment for a cold 8 months after TACE. CT showed 87% shrinkage of the tumor shadow. This method could be a new therapeutic option for non-small cell lung cancer with little side effects, particularly in older patients or those with pulmonary complications. PMID:23863736

Kunisada, Keita; Ishikawa, Hideo; Takafuji, Jun; Komuta, Kiyoshi

2013-07-01

133

[A case of idiopathic ventricular tachycardia in a 14-year-old obese patient due to golden berry fruit extract pills for weight loss].  

PubMed

Several studies have determined an association between obesity and increased risk of cardiac arrhythmia. Currently, due to the increased frequency of obesity, food-, plant-, and drug-based therapies for weight loss have gained great attention. A 14-year-old female patient presented with complaints of palpitation of one-hour onset. Blood pressure was 110/70 mmHg and peripheral pulses were present. She had been using golden berry extract pill three times a day for 10 days. The electrocardiogram showed nonsustained monomorphic ventricular tachycardia (VT). Echocardiographic examination and cardiac magnetic resonance imaging (MRI) were normal. She returned to sinus rhythm following amiodarone infusion. She refused the electrophysiologic study, which plays a vital role in the diagnosis and establishment of the appropriate therapy. Although there was no decrease in body mass index (BMI) of the patient during the two-year follow-up, she had no complaint or evidence of VT on intermittent rhythm Holter studies. This case suggests the primary role of golden berry extract use in the development of VT, rather than obesity. PMID:23917008

Sim?ek, Hakk?; Do?an, Adnan; Sahin, Musa; Gümrükçüo?lu, Hasan Ali

2013-07-01

134

70-year old female patient with mismatch between hematocrit and hemoglobin values: the effects of cold agglutinin on complete blood count  

PubMed Central

Introduction: There are a number of pre-analytical and analytical factors, which cause false results in the complete blood count. The present case identifies cold agglutinins as the cause for the mismatch between hematocrit and hemoglobin values. Materials and methods: 70-year old female patient had a history of cerebrovascular diseases and rheumatoid arthritis. During routine laboratory examination, the patient had normal leukocyte and platelet counts; however, the hemoglobin (Hb: 105 g/L) and hematocrit (HCT: 0.214 L/L) results were discordant. Hemolysis, lipemia and cold agglutinin were evaluated as possible reasons for the mismatch between hematocrit and hemoglobin values. Results: First blood sample was slightly hemolysed. Redrawn sample without hemolysis or lipemia was analyzed but the mismatch became even more distinct (Hb: 104 g/L and HCT: 0.08 L/L). In this sample, the titration of the cold agglutinin was determined and found to be positive at 1:64 dilution ratios. After an incubation of the sample at 37°C for 2 hours, reversibility of agglutination was observed. Conclusion: We conclude that cold agglutinins may interfere with the analysis of erythrocyte and erythrocyte-related parameters (HCT, MCV, MCH and MCHC); however, Hb, leukocyte and platelet counts are not affected. PMID:25351358

Ercan, Serif; Cal?skan, Mustafa; Koptur, Erhan

2014-01-01

135

A novel (paternally inherited) duplication 13q31.3q32.3 in a 12-year-old patient with facial dysmorphism and developmental delay.  

PubMed

We report a 12-year-old boy referred to the Clinical Genetics service in view of facial dysmorphism, learning difficulties and autistic spectrum disorder. 60K arrayCGH revealed an 8.2-Mb duplication on chromosome 13q31.3q32.3, which was paternally inherited. This specific duplication on chromosome 13 has not been previously reported in the medical literature, and there are no familial or de novo patients with the same duplication breakpoints. This region contains 24 OMIM genes, including the glypicans GPC5 and GPC6, and the ZIC2 gene. We discuss the relevance of this chromosome imbalance and discuss the impact of this duplication on our patient's phenotype. Given that the duplication on 13q was paternally inherited, and although initially thought to be of uncertain significance, on exploring the family history further, it became apparent that the father had learning difficulties as a child and previous surgery for congenital diaphragmatic hernia. Here we explore the phenotype in association with this novel duplication on chromosome 13q and add to the existing literature on array findings within this region. PMID:25337073

Atack, E; Fairtlough, H; Smith, K; Balasubramanian, M

2014-08-01

136

Unintended Harm and Benefit of the Implantable Defibrillator in an Unfortunate 19-Year-Old Male: Featuring a Sequence of Rare Life-threatening Complications of Cardiac Procedures.  

PubMed

All procedures have inherent risk. Our patient endured a sequence of rare life-threatening complications from commonly preformed procedures. The sequence of these complications was; large pericardial effusion post implantable cardioverter-defibrillator (ICD) implantation with echocardiographic signs of tamponade, left main narrowing post radiofrequency ablation, and late stent thrombosis post coronary intervention with a bare metal stent. All these occurred to one unfortunate young man. Furthermore, our patient demonstrated an unintended benefit of ICD which saved his life. PMID:24086098

Daoulah, Amin; Ocheltree, Ali; Lotfi, Amir; Ocheltree, Sara; Alsheikh-Ali, Alawi A; Al-Habib, Abdul-Karim; El-Sayed, Osama; Haneef, Ali

2013-01-01

137

A Quantitative Study on the Condom-Use Behaviors of Eighteen- to Twenty-Four-Year-Old Urban African American Males  

PubMed Central

This research study sought to develop, pilot test, and assess a brief male-centered condom promotion program for urban young adult African American males. For study implementation, both qualitative and quantitative research methods were used, and the project was guided by tenets of two common but integrated theoretical frameworks in HIV/sexually transmitted disease (STD) prevention research: the social cognitive theory and the stages of change model. The purpose of the qualitative component was to identify and explore condom-use barriers and facilitators while that of the quantitative component was to identify the prevalence of condom-related behaviors and the feasibility of program administration. After recruitment of study participants from hang-out spots and street intercepts, study participants were self-administered a baseline survey regarding their perceived condom-use behaviors prior to random assignment to program conditions (a condom promotion program and an attention-matched comparison condition). In this paper, we report the findings from the analyses of the quantitative baseline survey data. While the occurrence of HIV/STD-related risk behaviors were highly prevalent among this population; importantly, regression analyses revealed that sexual debut, favorable attitudes toward condom use, social or personal connectedness to HIV/STDs, health beliefs, perceived susceptibility, unprotected sexual encounters, and refusal skills were predictive of retrospective (i.e., prior 30 days) condom use while positive reasons (pros) to use condoms, condom-use beliefs, condom-carrying, health belief, unprotected sexual encounters and refusal skills were also predictive of prospective (i.e., future 30 days) condom-use intentions. The implications and limitations of this study are described and recommendations provided for program development. PMID:17518523

KENNEDY, STEPHEN B.; NOLEN, SHERRY; APPLEWHITE, JEFFREY; PAN, ZHENFENG; SHAMBLEN, STEPHEN; VANDERHOFF, KENNETH J.

2007-01-01

138

Unexpected finding of T-cell lymphoma in a previously healthy 16-year-old patient after a thorax trauma: a case report  

PubMed Central

Introduction We describe the clinical course and emphasize the difficulties in diagnosing T-cell lymphoblastic lymphoma. The differential diagnostic difficulties have previously been described in regard to pneumonia, but to the best of the authors’ knowledge this is the first case report to describe lymphoma in relation to trauma. Case presentation A previously healthy 16-year-old Danish boy presented to our hospital with chest pain and accentuated protruding thoracic veins. Ten days prior to hospitalization he had suffered a blunt thoracic trauma while playing soccer. After drainage of an excessive amount of pleural fluid, he developed severe respiratory distress. A chest tube was inserted and he was transferred to a level 1 trauma centre. Here, a computed tomography scan unexpectedly revealed significantly swollen mediastinal and retroperitoneal lymph nodes, and he was later diagnosed with T-cell lymphoblastic lymphoma. Conclusions This case emphasizes the importance of reacting to an unexplained large amount of pleural fluid after a patient suffers thoracic trauma and to consider possible underlying causes. This report is mainly addressed to emergency personnel, but it is also relevant to pediatricians, surgeons, anesthesiologists, and general practitioners. PMID:25403976

2014-01-01

139

A 37-year-old spinal cord-injured female patient, transplanted of multipotent stem cells from human UC blood, with improved sensory perception and mobility, both functionally and morphologically: a case study  

Microsoft Academic Search

HLA-matched UC blood-derived multipotent stem cells were directly transplanted into the injured spinal cord site of a 37-year-old female patient suffering from spinal cord injury (SPI). In this case, human cord blood (UCB)-derived multipotent stem cells improved sensory perception and movement in the SPI patient's hips and thighs within 41 days of cell transplantation. CT and MRI results also showed

K-S Kang; SW Kim; YH Oh; JW Yu; K-Y Kim; C-H Song; H Han

2005-01-01

140

3-D printout of a DICOM file to aid surgical planning in a 6 year old patient with a large scapular osteochondroma complicating congenital diaphyseal aclasia.  

PubMed

A 6 year old girl presented with a large osteochondroma arising from the scapula. Radiographs, CT and MRI were performed to assess the lesion and to determine whether the lesion could be safely resected. A model of the scapula was created by post-processing the DICOM file and using a 3-D printer. The CT images were segmented and the images were then manually edited using a graphics tablet, and then an STL-file was generated and a 3-D plaster model printed. The model allowed better anatomical understanding of the lesion and helped plan surgical management. PMID:22690278

Tam, Matthew D; Laycock, Stephen D; Bell, Duncan; Chojnowski, Adrian

2012-01-01

141

Generalized odontodysplasia in a 5-year-old patient with Hallermann-Streiff syndrome: clinical aspects, cone beam computed tomography findings, and conservative clinical approach.  

PubMed

This article aims to report the main clinical aspects, cone beam computed tomography (CBCT) findings, and conservative oral rehabilitation in a child born from a consanguineous marriage who presented with Hallermann-Streiff syndrome (HSS) and generalized odontodysplasia. A 5-year-old girl presented with a diagnosis of HSS for oral evaluation. Radiographically, all teeth showed wide pulp chambers and roots with thin dentinal walls and open apices, resembling ghost teeth and indicating a diagnosis of odontodysplasia. Oral rehabilitation consisted of partial dentures that were regularly adjusted to conform the device with the pattern of growth and development of the child. CBCT scan provided great insight into HSS, allowing a detailed view of the morphologic aspects and associated trabecular bone pattern. Treatment of these 2 rare conditions in young children must consider the stage of growth and development. Although extremely rare in HSS, odontodysplasia should be investigated and conservatively managed in young children. PMID:25047934

Damasceno, Juliana Ximenes; Couto, José Luciano Pimenta; Alves, Karla Shangela da Silva; Chaves, Cauby Maia; Costa, Fábio Wildson Gurgel; Pimenta, Alynne de Menezes Vieira; Fonteles, Cristiane Sá Roriz

2014-08-01

142

Diagnosis of cardiac metastasis from cervical cancer in a 33-year-old patient using multimodal imaging studies: a case report and literature review.  

PubMed

We report a case of a 33-year-old woman with emergency admission due to dyspnoea and fever. History included squamous cell carcinoma of the cervix in complete remission. Contrast-enhanced computed tomography (CT) scanning of the chest, which was indicated to rule out pneumonia, revealed an infiltrative cardiac mass. Further assessment of the tumour by echocardiography and cardiac magnetic resonance imaging (MRI) showed transmural infiltration of the apical interventricular septum with a mass extending into the left and right ventricle cavities. The mass was highly suspicious for a cardiac metastasis. Cardiac metastases from cervical cancer are extremely rare. Recurrence of cervical carcinoma involving the heart should be considered even after a curative therapy approach. Non-invasive imaging plays a paramount role in investigating cardiac masses. Echocardiography, CT and MRI are complementary imaging modalities for complete work-up of intracardiac lesions. PMID:25346849

Schawkat, Khoschy; Hoksch, Beatrix; Schwerzmann, Markus; Puig, Stefan; Klink, Thorsten

2014-09-01

143

Diagnosis of cardiac metastasis from cervical cancer in a 33-year-old patient using multimodal imaging studies: a case report and literature review  

PubMed Central

We report a case of a 33-year-old woman with emergency admission due to dyspnoea and fever. History included squamous cell carcinoma of the cervix in complete remission. Contrast-enhanced computed tomography (CT) scanning of the chest, which was indicated to rule out pneumonia, revealed an infiltrative cardiac mass. Further assessment of the tumour by echocardiography and cardiac magnetic resonance imaging (MRI) showed transmural infiltration of the apical interventricular septum with a mass extending into the left and right ventricle cavities. The mass was highly suspicious for a cardiac metastasis. Cardiac metastases from cervical cancer are extremely rare. Recurrence of cervical carcinoma involving the heart should be considered even after a curative therapy approach. Non-invasive imaging plays a paramount role in investigating cardiac masses. Echocardiography, CT and MRI are complementary imaging modalities for complete work-up of intracardiac lesions. PMID:25346849

Hoksch, Beatrix; Schwerzmann, Markus; Puig, Stefan; Klink, Thorsten

2014-01-01

144

Parotid sialolithiasis in a two-year-old boy  

PubMed Central

Sialolithiasis is caused by the obstruction of a salivary gland or its excretory duct by the formation of calcareous concretions or sialoliths; this results in salivary ectasia and provokes subsequent dilation of the salivary gland. Sialolithiasis is relatively common, accounting for 30% of salivary diseases; however, it is rarely observed in childhood. This case report describes a 2-year-old male patient who complained of a painful swelling over the right cheek, and presented with palpable stones and pus discharge from the orifice of the right Stensen's duct. Computerized tomography of the neck confirmed the diagnosis, and the patient received intravenous empiric antibiotics combined with intraoral sialolithotomy. We also provide a review of the spectrum of concepts regarding the pathogenesis, diagnosis, and treatment of sialolithiasis. PMID:24244214

Kim, Do Hoon; Song, Woo Sun; Kim, Yeong Jin

2013-01-01

145

Pulmonary Hernia in a Two-Year-Old Child  

PubMed Central

Pulmonary hernia, also known as lung herniation or intercostal herniation, is best explained as the lung parenchyma protruding beyond the confines of the thoracic wall. This rare finding can be classified as congenital or acquired. Acquired pulmonary herniations are often the complication of blunt or penetrating trauma to the chest wall. This report describes a two-year-old male who fell onto a rigid post, striking his left lower chest. Imaging studies demonstrated a small pneumothorax as well as pulmonary herniation. The patient underwent a diagnostic thoracoscopy and repair of a pulmonary hernia within the 7th intercostal space without complication. In this case report, we aim to add to the limited body of existing literature on the surgical management of pulmonary hernias.

Walters, Bryan S.; Agnoni, Alysia A.; Coppola, Christopher P.; Scorpio, Ronald J.; Kennedy, Alfred P.

2014-01-01

146

Prevalence and Prognostic Influence of Peripheral Arterial Disease in Patients ?40 Years Old Admitted into Hospital Following an Acute Coronary Event  

Microsoft Academic Search

ObjectiveA significant proportion of patients with ischemic heart disease have associated peripheral arterial disease (PAD), but many are asymptomatic and this condition remains underdiagnosed. We aimed to study the prevalence of PAD in patients with an acute coronary syndrome (ACS) and to evaluate its influence in hospital clinical outcomes.

V. Bertomeu; P. Morillas; J. R. Gonzalez-Juanatey; J. Quiles; J. Guindo; F. Soria; A. Llacer; I. Lekuona; P. Mazón; C. Martín-Luengo; L. Rodriguez-Padial

2008-01-01

147

Recurrent hemoptysis in a 62-year-old smoker  

PubMed Central

Tracheal papillary adenoma is a rare benign tumor. We report a case of papillary adenoma in a 62-year-old male smoker who presented with recurrent hemoptysis. The tumor was located in the upper third of trachea and forceps biopsy through flexible bronchoscopy was uncomplicated and diagnostic. PMID:23741099

Gowrinath, Karanam; Ramakrishna, Baddukonda Appala; Shanthi, Vissa; Sujatha, Gogineni

2013-01-01

148

How Grammatical Are 3-Year-Olds?  

ERIC Educational Resources Information Center

Purpose: This study investigated the level of grammatical accuracy in typically developing 3-year-olds and the types of errors they produce. Method: Twenty-two 3-year-olds participated in a picture description task. The percentage of grammatical utterances was computed and error types were analyzed. Results: The mean level of grammatical accuracy…

Eisenberg, Sarita L.; Guo, Ling-Yu; Germezia, Mor

2012-01-01

149

Primary Sjögren syndrome in a 2-year-old patient: role of the dentist in diagnosis and dental management with a 6-year follow-up.  

PubMed

BACKGROUND. Primary Sjögren syndrome is a rare autoimmune disease, especially in children, mainly affecting girls (77%), and usually diagnosed around 10 years of age. Diagnosis during childhood is difficult, especially because of the diversity of the clinical presentation and difficulty obtaining reliable history data, accounting for a higher frequency of underdiagnosed cases. Differential conditions should be considered, especially the ones that promote xerostomia, such as diabetes, ectodermal dysplasia, rheumatoid arthritis, scleroderma, systemic lupus erythematosus, sarcoidosis, lymphoma, HIV and HTLV infection. Conditions associated with parotid enlargement should also be excluded, including juvenile recurrent parotitis (JRP), sialadenosis, sarcoidosis, lymphoma, infectious parotitis caused by streptococcal and staphylococcal infections, viral infections (paramyxovirus, Epstein-Barr virus, cytomegalovirus, and parvovirus), and diffuse infiltrative lymphocytosis syndrome (associated with HIV infection), and rare congenital conditions, such as polycystic parotid disease. CASE REPORT. A paediatric female patient was referred to our clinic for dental treatment complaining about dry mouth, oral discomfort, and dysphagia. The patient presented five of the required criteria to establish the diagnosis of pSS, including ocular symptoms, oral symptoms, evidence of keratoconjunctivitis sicca, focal sialadenitis confirmed by minor salivary gland biopsy, and evidence of major salivary gland involvement. Our patient did not have positive SS-A and SS-B autoantibodies. According to the literature, about 29% of individuals with pSS can present seronegativity for SS-A (anti-Ro) antibodies and about 33% can present seronegativity for SS-B (anti-La) antibodies. CONCLUSION. To the best of our knowledge, this is the youngest patient reported in the scientific English literature with pSS. Primary Sjögren syndrome has a wide clinical and immunologic spectrum and may progress with increased morbidity. Clinicians must be aware of the development of pSS in such an early age and exclude all possible differential findings to provide early diagnosis and treatment. PMID:21623979

De Oliveira, Marcio Augusto; De Rezende, Nathalie Pepe Medeiros; Maia, Célia Márcia Fernandes; Gallottini, Marina

2011-11-01

150

Coexistence of renal cell carcinoma of clear cell type with sarcomatoid cell type component and adrenal mature ganglioneuroma with myelolipoma - a case of 69-year-old female patient.  

PubMed

This report presents a case of 69-year-old woman, who was operated due to renal tumor. Apart from renal neoplasm, the adjacent adrenal gland contained another one tumor in medulla of the organ. The renal lesion was diagnosed renal cell carcinoma, clear cell type with undifferentiated cell sarcomatoid component. The adrenal neoplasm was composed of wavy S100-positive, Schwann-like cells and dispersed chromogranin A-reactive ganglion cells to be consistent with mature ganglioneuroma. It was accompanied by coexistent myelolipoma that contained hematopoietic cells including clearly visible megakaryocytes and foci of fat. To our knowledge, our paper is the first to report sporadic clear cell renal cell carcinoma with sarcomatoid cell type component and mature adrenal ganglioneuroma with myelolipoma in the same patient. PMID:24969996

Lewitowicz, Piotr; Wincewicz, Andrzej; Horecka-Lewitowicz, Agata; Matykiewicz, Jaros?aw; Kozie?, Dorota; G?uszek, Stanis?aw; Sulkowski, Stanis?aw

2014-01-01

151

[Giant intracranial aneurysm in three years old boy: case report].  

PubMed

Cerebral aneurysms are rare in the pediatric age group and differ from adults' aneurysms in size, localization and incidence. We report a 3-year-old boy with giant middle cerebral artery aneurysms who presented with subarachnoid hemorrhage. The patient was submitted to surgical treatment and the postoperative period was uneventful. PMID:16917634

de Tella, Osvaldo Inácio; Crosera, João Francisco; Herculano, Marco Antonio; de Paiva Neto, Manoel Antonio

2006-06-01

152

Pathology Case Study: A 42-Year-Old Man with Hip Pain  

NSDL National Science Digital Library

This is a genitourinary pathology case study presented by the University of Pittsburgh Department of Pathology in which a 42-year-old male has hip pain and an elevated PSA. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in genitourinary pathology.

Hakam, Ardeshir; Nine, Jeff S.

2007-08-14

153

47-year-old man with left leg numbness.  

PubMed

A 47-year-old white male with a history of uveitis, hypercalcemia and nephrolithiasis presented with acute onset partial seizure. On exam he had decreased sensation to light touch on his left lower extremity. A Brain MRI revealed a right frontal mass, which was initially thought to be a metastatic lesion or a primary brain tumor. However, biopsy of the lesion revealed it to be a non-caseating granulomatous lesion consistent with neurosarcoidosis. PMID:23432649

Mahta, Ali; Kim, Ryan Y; Saad, Ali G; Kesari, Santosh

2013-03-01

154

Confirmed testicular torsion in a 67 year old  

PubMed Central

Torsion amongst the elderly population is rarely described. This case presents the oldest surgically confirmed case of testicular torsion, in a 67-year-old male, within the UK. Presenting to the emergency department with a 10-day history of left-sided testicular pain, initially treated with antibiotics. There was no pyrexia or urinary symptoms and negative urine dipstick. In adults above the age of 40, likely diagnoses include epididymo-orchitis, epididymitis, neoplasm or hydrocele. Clinical differentiation with epididymo-orchitis can be difficult in any age range. Clinical signs such as fever, elevated C-reactive protein and positive urine dipstick test are suggestive of epididymo-orchitis/orchitis. This case study demonstrates that testicular torsion can occur at any age, and clinical suspicion should always be high in patients presenting with testicular pain and a negative urine dipstick, regardless of age. Although risk in this subgroup is low, the identification of a potentially reversible testicular abnormality should be of high priority. PMID:24876322

Farrington, Nicola L.; Lucky, Marc A.; Barnes, Thomas; Calvert, Robert

2014-01-01

155

Confirmed testicular torsion in a 67 year old.  

PubMed

Torsion amongst the elderly population is rarely described. This case presents the oldest surgically confirmed case of testicular torsion, in a 67-year-old male, within the UK. Presenting to the emergency department with a 10-day history of left-sided testicular pain, initially treated with antibiotics. There was no pyrexia or urinary symptoms and negative urine dipstick. In adults above the age of 40, likely diagnoses include epididymo-orchitis, epididymitis, neoplasm or hydrocele. Clinical differentiation with epididymo-orchitis can be difficult in any age range. Clinical signs such as fever, elevated C-reactive protein and positive urine dipstick test are suggestive of epididymo-orchitis/orchitis. This case study demonstrates that testicular torsion can occur at any age, and clinical suspicion should always be high in patients presenting with testicular pain and a negative urine dipstick, regardless of age. Although risk in this subgroup is low, the identification of a potentially reversible testicular abnormality should be of high priority. PMID:24876322

Farrington, Nicola L; Lucky, Marc A; Barnes, Thomas; Calvert, Robert

2014-01-01

156

A 72 year old woman with ALCAPA  

Microsoft Academic Search

ALCAPA syndrome (anomalous origin of the left coronary artery from the pulmonary artery), which causes the left coronary artery to grow with an anomalous origin from the pulmonary artery, is a rare disease which may result in myocardial infarction, congestive heart failure, and sometimes death during the early infantile period. A 72 year old woman with ALCAPA syndrome is presented.

C Fierens; W Budts; B Denef; F Van de Werf

2000-01-01

157

100-Year Old Adobe Building Destroyed  

USGS Multimedia Gallery

A one hundred year old adobe building in Talca, Chile suffered near-total collapse during the M 8.8 earthquake on Feb. 27, 2010. Adobe, which is made of clay, sand and straw, is no longer used as a building material in Chile, but ancient structures are still common and can pose a hazard to their occ...

2010-03-30

158

Conversational Topics of Four-Year-Olds.  

ERIC Educational Resources Information Center

Conversational samples of 10 dyads of 4-year-old children during play were analyzed. All dyads evidenced some lengthy topics (13-91 utterances), characterized by 3 text-level functions: enacting scenarios, describing, and problem solving. Three-fourths of all dialogues were considered relatively short. (Author/JDD)

Schober-Peterson, Debra; Johnson, Cynthia J.

1989-01-01

159

Correction of skeletal class III in a growing male patient by reverse pull facemask.  

PubMed

The following case report describes the management of a 6-year-old male patient in early mixed dentition with a mesial step molar relation, an anterior reverse overjet, and skeletal Class III due to a slightly deficient maxilla. The treatment plan included protraction of the maxilla by a reverse pull Petit type facemask for 10 months followed by 15 months of active retention by a Frankel III appliance. PMID:21985889

Kapoor, P; Kharbanda, O P

2011-01-01

160

Sebaceous trichofolliculoma of the cheek in a 65-year-old man.  

PubMed

Sebaceous trichofolliculoma is considered as hamartomatous lesion with follicular differentiation. In this study, we demonstrated a classic histopathologic picture of sebaceous trichofolliculoma in a 65-year-old male presented with large sized right cheek swelling. PMID:25372425

Abdou, Ag; Asaad, Ny

2014-11-01

161

Elective transplant pneumonectomy in a 38-year-old man.  

PubMed

Transplant pneumonectomy is a rarely performed procedure. It is occasionally carried out in the course of retransplantation. To our knowledge, resection of a transplanted lung without its replacement and with successful outcome in the adult has not been previously reported. We present a case of elective left transplant pneumonectomy in a 38-year-old man 6 years after left single-lung transplant. At 12 months after resection, the patient remains well, with good exercise tolerance. PMID:16102460

Onyeaka, C V Patrick; Alexiou, Christos; Rocco, Gaetano; Hopkinson, David N; Suvarna, S Kim; Braidley, Peter C; Locke, Tim J

2005-08-01

162

Giant cephalhematoma in a 15-year-old boy  

Microsoft Academic Search

BACKGROUNDThe term “cephalhematoma” is applied to a collection of blood under the periosteum of a skull bone. It most frequently occurs in the neonatal period and is rare at other times of life.METHODS AND RESULTSWe report on a 15-year-old boy with a subperiosteal hematoma involving the whole cranial surface. Surgical drainage was performed. In the immeidate postoperative course, the patient

Jesus Aguas; Cesareo Conde; Gemma G Fructuoso; Francisco J Mondelo; Enrique Ferrer

1995-01-01

163

Development of 5- and 10-year-old pediatric phantoms based on polygon mesh surfaces  

SciTech Connect

Purpose: The purpose of this study is the development of reference pediatric phantoms for 5- and 10-year-old children to be used for the calculation of organ and tissue equivalent doses in radiation protection. Methods: The study proposes a method for developing anatomically highly sophisticated pediatric phantoms without using medical images. The 5- and 10-year-old male and female phantoms presented here were developed using 3D modeling software applied to anatomical information taken from atlases and textbooks. The method uses polygon mesh surfaces to model body contours, the shape of organs as well as their positions, and orientations in the human body. Organ and tissue masses comply with the corresponding data given by the International Commission on Radiological Protection (ICRP) for the 5- and 10-year-old reference children. Bones were segmented into cortical bone, spongiosa, medullary marrow, and cartilage to allow for the use of micro computer tomographic ({mu}CT) images of trabecular bone for skeletal dosimetry. Results: The four phantoms, a male and a female for each age, and their organs are presented in 3D images and their organ and tissue masses in tables which show the compliance of the ICRP reference values. Dosimetric data, calculated for the reference pediatric phantoms by Monte Carlo methods were compared with corresponding data from adult mesh phantoms and pediatric stylized phantoms. The comparisons show reasonable agreement if the anatomical differences between the phantoms are properly taken into account. Conclusions: Pediatric phantoms were developed without using medical images of patients or volunteers for the first time. The models are reference phantoms, suitable for regulatory dosimetry, however, the 3D modeling method can also be applied to medical images to develop patient-specific phantoms.

Melo Lima, V. J. de; Cassola, V. F.; Kramer, R.; Oliveira Lira, C. A. B. de; Khoury, H. J.; Vieira, J. W. [Department of Anatomy, Federal University of Pernambuco, Avenida Professor Moraes Rego 1235, CEP 50670-901, Recife, Pernambuco (Brazil); Department of Nuclear Energy, Federal University of Pernambuco, Avenida Professor Luiz Freire 1000, CEP 50740-540, Recife, Pernambuco (Brazil); Federal Institute of Education, Science and Technology of Pernambuco, Avenida Professor Luiz Freire 500, CEP 50740-540, Recife, Pernambuco, Brazil and Polytechnic School of Pernambuco, University of Pernambuco, Rua Benfica 455, CEP 50751-460, Recife, Pernambuco (Brazil)

2011-08-15

164

Zygomatic arch fracture in a 40-year-old woman.  

PubMed

This case describes an injury to a 40-year-old woman, employed as a softball team coach, who presented to an emergency department (ED) after sustaining a line drive hit to the right side of the face with a softball during practice. Upon arrival to the ED, the patient complained of moderate pain, swelling, and bruising over the right side of her midface area. After evaluation in the ED, the patient received a diagnosis of a zygomatic arch fracture that was further managed by an occupational medicine nurse practitioner, a plastic surgeon, and an ear, nose, and throat (ENT) physician specialist. PMID:25356889

Ramponi, Denise; White, Thomas

2014-01-01

165

11 year-old girl undergoing scoliosis surgery.  

PubMed

We report the case of an 11-year-old girl operated on for a severe left thoracolumbar scoliosis. Pedicular screw insertion and rod positioning was technically successful, but five days later, for signs of an early infection, the wound revised and unexpectedly the patient died during surgery. Autopsy recognized a diffuse cerebral cortical venous air embolism as the cause of death and excluded pulmonary embolism and associated cardiac defects.This is the first and unique case describing a fatal paradoxical air venous cerebral embolism in a pediatric patient undergone spine surgery: the possible mechanism involving azygos and jugular veins systems is discussed. PMID:22697383

De-Giorgio, Fabio; Arena, Vincenzo; Turturro, Francesco; d'Aloja, Ernesto; Miscusi, Massimo

2012-07-01

166

Acoustic emphasis in four year olds  

PubMed Central

Acoustic emphasis may convey a range of subtle discourse distinctions, yet little is known about how this complex ability develops in children. This paper presents a first investigation of the factors which influence the production of acoustic prominence in young children’s spontaneous speech. In a production experiment, SVO sentences were elicited from 4 year olds who were asked to describe events in a video. Children were found to place more acoustic prominence both on ‘new’ words and on words which were ‘given’ but had shifted to a more accessible position within the discourse. This effect of accessibility concurs with recent studies of adult speech (Dahan, Tanenhaus, & Chambers, 2002, Watson, Arnold & Tanenhaus 2005). We conclude that, by age four, children show appropriate, adult-like use of acoustic prominence, suggesting sensitivity to a variety of discourse distinctions. PMID:18070621

Wonnacott, Elizabeth; Watson, Duane G.

2008-01-01

167

Physical Fitness and Cognitive Function in an 85YearOld Community-Dwelling Population  

Microsoft Academic Search

Background: Little is known about the association between physical fitness and cognitive function in very elderly people (over 80 years of age). Objectives: To evaluate that relationship in 85-year-old community-dwelling individuals. Methods: Out of 207 participants (90 males, 117 females) who were 85 years old and community-dwelling, 205 completed the Mini-Mental State Examination (MMSE) for evaluating cognitive function. The numbers

Y. Takata; T. Ansai; I. Soh; Y. Kimura; Y. Yoshitake; K. Sonoki; S. Awano; S. Kagiyama; A. Yoshida; I. Nakamichi; T. Hamasaki; T. Torisu; K. Toyoshima; T. Takehara

2008-01-01

168

Accidental dextromethorphan ingestions in children less than 5 years old  

Microsoft Academic Search

Introduction  The purpose of this study is to evaluate the clinical presentation of accidental dextromethorphan (DXM) ingestions in children\\u000a <5 years old. Two consecutive years of poison center patient encounters were reviewed. Data including age, outcomes, amount\\u000a of DXM ingested, co-ingestions, vital signs, clinical manifestations, hospital admissions, and mortality were abstracted.\\u000a Data were analyzed using descriptive statistics.\\u000a \\u000a \\u000a \\u000a Discussion  A total of 304

Frank LoVecchio; Anthony Pizon; Bradley Riley; Leslie Matesick; Sean O’Patry

2008-01-01

169

A 40-year-old woman 'off legs'.  

PubMed

We present the case of a 40-year-old woman with progressive lower-limb weakness resulting in an inability to mobilise independently. This was associated with a degree of confusion and shortness of breath on exertion. This case illustrates rare and severe complications of vitamin B(12) deficiency, namely subacute combined degeneration of the spinal cord, megaloblastic anaemia and impaired cognitive function. The patient's condition improved considerably with adequate early resuscitation, followed by administration of synthetic vitamin B(12) analogues and neuro-rehabilitation. PMID:23291820

Mehrotra, Prerna; Bhalla, Ashish

2013-01-01

170

[Decompensated liver cirrhosis caused by galactosemia in a 52-year-old man].  

PubMed

A 52-year-old oligophrenic man hospitalized for esophageal hemorrhage had histologically proven liver cirrhosis and died from massive rehemorrhage. As a neonate he had survived severe jaundice, had had delayed psychomotor development and remained severely retarded. At age 15 years, bilateral cataracts had been excised and from 18 to 25 years he had had occasional grand mal seizures. The triad oligophrenia, liver cirrhosis and cataracts, prompted suspicion of galactosemia. Deficiency of galactose-1-phosphate uridyltransferase was demonstrated in blood and post mortem tissue. At autopsy, liver cirrhosis and esophageal varices were confirmed and unilateral chronic pyelonephritis, bilateral nephrolithiasis and testicular atrophy were found. There was not brain pathology. The patient appeared to be the oldest nondiagnosed galactosemic and the first male patient in whom hypogonadism was documented. PMID:7455652

Vogt, M; Gitzelmann, R; Allemann, J

1980-11-22

171

Pilon Fracture: A Case Report of a 45-Year-Old Dental Technician  

PubMed Central

Pilon fractures are complex and difficult-to-treat fractures of the lower extremity that account for about 1% of all lower extremity fractures and up to 10% of tibial fractures. The injury is caused by high energy axial load either from motor vehicle accidents or a fall from height. The treatment of these fractures has caused controversy among surgeons due to mixed outcomes. Here we report a case of pilon fracture in a 45 year old male patient who has sustained the injury as a result of a fall from a height of approximately 12 feet. We describe why it is absolutely crucial that the patient is treated with external fixation initially and evaluate its merits and drawbacks as well as ways to minimize the complications associated with external fixation of open intra-articular distal tibial fractures. PMID:25408785

Mafi, Pouya; Stanley, James; Hindocha, Sandip; Mafi, Reza

2014-01-01

172

When are you old enough in England? 16 years old +  

E-print Network

When are you old enough in England? 16 years old + can get married with one parent's consent can if accompanied by a person over 18 can play the National Lottery can work full time 17 years old + can obtain years old + can buy alcohol can drink alcohol in a pub can buy tobacco/cigarettes can appear before

Applebaum, David

173

Multifocal tumoral calcinosis in a 4-year-old girl  

PubMed Central

Patient: Female, 4 Final Diagnosis: Tumoral calcinosis Symptoms: Hard immobile mass Medication: — Clinical Procedure: — Specialty: Surgery Objective: Congenital defects Background: Tumoral calcinosis is an uncommon condition associated with the deposition of painless calcific masses. It is more common in childhood or early adolescence of African-American females. Case Report: We present a case of a 4-year-old girl with tumoral calcinosis treated surgically. The case is rather rare in terms of the age of the patient and the localization of the masses (gluteal site). In our patient, the biochemical findings were normal, except for hyperphosphatemia and elevated alkaline phosphatase. Conclusions: Total excision appears to lead to a good clinical outcome and a low incidence of local relapse. PMID:24644527

Sayar, Ilyas; Peker, Kemal; Kap?s?z, Alparslan; Bostanc?, Is?l Esen; Gürbüzel, Mehmet; Isik, Arda; Peker, Necla Ayd?n

2014-01-01

174

An Unusual Case Report of Rapunzel Syndrome Trichobezoar in a 3-Year-Old Boy  

PubMed Central

Rapunzel Syndrome is a rare trichobezoar, involving strands of swallowed hair extending as a tail through the duodenum, beyond the stomach. Trichobezoar usually occur in patients with history of trichotillomania, characterized by compulsive behavioral disorder of pulling own hairs, combined with trichophagia that consists of ingesting that hairs. It typically occurs in stomach and rarely affects the small intestine. Trichobezoars are more common in adolescent females. Common presentation is gastrointestinal tract obstruction with nausea and vomiting, gut perforation, acute pancreatic necrosis, obstructive jaundice, hypochromic anemia, vitamin B12 deficiency, weight loss, an abdominal mass, or other serious problems. Intestinal obstruction due to trichobezoar is extremely rare. We are here reporting a large trichobezoar in a 3-year-old male child who presented to the emergency department with thread protruding from mouth with no sign of hair loss on body. PMID:22223971

Jain, Manish; Solanki, Sohan Lal; Bhatnagar, Ankur; Jain, Pavan Kumar

2011-01-01

175

Choline associated hypersexuality in a 79-year-old man.  

PubMed

Hypersexuality, also referred to as sexually inappropriate behavior and sexual disinhibition, involves persistent, uninhibited sexual behaviors directed at oneself or at others, sometimes associated with neurodegenerative disorders. Choline is a water-soluble essential nutrient, used as a dietary supplement in different diseases. This report was aimed at considering choline intake as a possible cause of iatrogenic hypersexuality. After an evaluation, a 79-year-old man affected by memory loss was diagnosed with mild cognitive impairment and treated with oral choline. After 6 weeks of regular choline assumption, the patient showed a pathological increase in libido with sexual urges. As choline was withdrawn, the hypersexuality disappeared within 5 days. Since hypersexuality may be an underreported and overlooked adverse effect of drugs and dietary supplements acting on the cholinergic pathway, this should be considered when treating and counselling patients with inappropriate sexual behavior. PMID:23733158

Calabrò, Rocco Salvatore; Cordici, Francesco; Genovese, Carmelo; Bramanti, Placido

2014-01-01

176

Systemic lupus erythematosus in 50 year olds.  

PubMed Central

We compared the clinical and serological characteristics of 15 patients with onset of systemic lupus erythematosus after the age of 50 with those of 232 younger patients. The sex distribution was similar in both groups. All 15 patients were Caucasian. Autoimmune thyroiditis was found in 20% of the elderly patients. Initial manifestations, which presented more frequently in the older group, included thrombocytopenia (P < 0.05), sicca syndrome (P < 0.01) and cardiomyopathy (P < 0.005), whereas butterfly rash (P < 0.05) presented more frequently in the younger group. Analysis of cumulative clinical symptoms showed that butterfly rash (P < 0.05) and livedo reticularis (P < 0.05) were less frequent in the elderly. However, this group presented a significantly increased incidence of sicca syndrome (P < 0.005) and cardiomyopathy (P < 0.005). Antibodies to double-stranded DNA tended to occur less frequently in older patients (P < 0.05). PMID:1437923

Domenech, I.; Aydintug, O.; Cervera, R.; Khamashta, M.; Jedryka-Goral, A.; Vianna, J. L.; Hughes, G. R.

1992-01-01

177

28. Graffiti in north cells: '20 years old 4315 CD ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. Graffiti in north cells: '20 years old 4315 C-D Mamoru Yoshimoto 5/24/45 180 days Kumamoto'; '18 ' ' years old 1406-A Haruo Yokoi 6/17/45 270 days Nagoya'; '31 ' ' years old 5604-B Masaki Nishii 5/24/45 180 days Kumamoto'; '19 ' ' years old 1806-B Masaharu Yoshida 5/24/45 180 days Hiroshima'; 135mm lens with electronic flash illumination. - Tule Lake Project Jail, Post Mile 44.85, State Route 139, Newell, Modoc County, CA

178

Wellens' syndrome in a 24-year-old woman.  

PubMed

Wellens' syndrome refers to specific ECG abnormalities in the precordial T-wave segment, which are associated with critical stenosis of the proximal left anterior descending (LAD) coronary artery culminating in an acute anterior wall myocardial infarction (MI) if the patient is not urgently revascularised. We describe the youngest reported presentation of Wellens' syndrome in a 24-year-old woman with unstable chest pain, characteristic ECG changes and slight troponin biomarker elevation. This was initially unrecognised by the emergency department as unstable coronary syndrome and she subsequently progressed to an anterior non-ST elevation MI (NSTEMI). Her coronary angiogram showed critical narrowing of the proximal LAD which was successfully treated with a drug-eluting stent. PMID:23632614

Khan, Beenish; Alexander, John; Rathod, Krishnaraj Sinhji; Farooqi, Fahad

2013-01-01

179

The Prevalence of Common Cardiovascular Diseases among 17YearOld Israeli Conscripts  

Microsoft Academic Search

Background: There are only few reports on the prevalence of common cardiovascular disorders among adolescents. The previous studies focused on specific diseases, and screened relatively small samples. Objective: The aim of this study was to define the prevalence of different common cardiovascular disorders among 17-year-old Israeli conscripts. A comparison between the morbidity patterns of female and male adolescents was also

Yaron Bar-Dayan; Keren Elishkevits; Liav Goldstein; Avishay Goldberg; Nisim Ohana; Erez Onn; Yehezkel Levi; Yosefa Bar-Dayan

2005-01-01

180

Risk Factors for Speech Delay of Unknown Origin in Three-Year-Old Children.  

ERIC Educational Resources Information Center

Compared 100 three-year-olds with speech delay of unknown origin and 539 same-age peers with respect to 6 speech disorder variables; also examined abnormal hearing in a subset of 279 children. Found significant odds ratios only for low maternal education, male sex, and positive family history; a child with all 3 factors was 7.71 times as likely to…

Campbell, Thomas F.; Dollaghan, Christine A.; Rockette, Howard E.; Paradise, Jack L.; Feldman, Heidi M.; Shriberg, Lawrence D.; Sabo, Diane L.; Kurs-Lasky, Marcia

2003-01-01

181

Growth and Your 2- to 3-Year-Old  

MedlinePLUS

... With Us Growth and Your 2- to 3-Year-Old KidsHealth > Parents > Growth & Development > Growth > Growth and Your 2- to 3-Year-Old Print A A A Text Size What's ... Grow At the Doctor's Office During the third year of life, most toddlers gain about 4 pounds ( ...

182

Growth and Your 1- to 2-Year-Old  

MedlinePLUS

... With Us Growth and Your 1- to 2-Year-Old KidsHealth > Parents > Growth & Development > Growth > Growth and Your 1- to 2-Year-Old Print A A A Text Size What's ... in for many changes! By midway through this year, most babies are walking and learning to talk. ...

183

A 55 years old man with pulmonary alveolar microlithiasis.  

PubMed

Pulmonary alveolar microlithiasis (PAM) is a very rare diffuse chronic lung disease characterized by deposition of small spherules of calcium phosphate within the alveolar cavity. The disease is usually seen from birth up to 40 years of age and is usually diagnosed incidentally during radiography of the chest for other reasons. Most of patients are asymptomatic or having very mild symptoms and the majority of patients either have normal or restrictive pulmonary function test. Clinically, the course of the disease is different; it remains static in few patients or it may progress to pulmonary fibrosis, respiratory failure and cor pulmonale in others. In this case report, we present a 55-year-old man who presented with moderate shortness of breath which has progressed from mild symptoms with in the previous years. His chest high-resolution CT scan showed diffusely scattered, ill-defined little shadowy micronodules which involve the left lung; lingula and left lower lobe in particular. A lung biopsy confirmed the diagnosis of PAM. He was followed up for 1 year with treatment by steroid and alendronate, and no progression was noticed in fact improvement in pulmonary function test noticed. This is the first case report of PAM in Kurdistan. PMID:25125824

Saeed, Rebeen R; Ali, Kosar M

2014-07-01

184

A retrospective study of tonsillectomy in the under 2-year-old child: indications, perioperative management, and complications  

Microsoft Academic Search

Objective: To retrospectively review the experience with tonsillectomy in the under 2-year-old child at an urban children's hospital. Methods: The medical records of 94 patients under 2 years old undergoing tonsillectomy between May 1, 1995, and May 31, 2000, were reviewed. The methods of tonsil and adenoid excision were noted, as was the use of perioperative steroids, antibiotics, and antiemetics.

Andreas H. Werle; Pamela J. Nicklaus; Daniel J. Kirse; Daniel E. Bruegger

2003-01-01

185

Primary pleural angiosarcoma in a 63-year-old gentleman.  

PubMed

Primary pleural angiosarcomas are extremely rare. As of 2010, only around 50 case reports have been documented in the literature. Herein, we report the case of a 63-year-old gentleman who presented with a 3-month history of right-sided chest pain, dyspnea, and hemoptysis. Chest X-ray showed bilateral pleural effusion with partial bibasilar atelectasis. Ultrasound-guided thoracocentesis showed bloody and exudative pleural fluid. Cytologic examination was negative for malignant cells. An abdominal contrast-enhanced computed tomography (CT) scan showed two right diaphragmatic pleural masses. Whole-body positron emission tomography/computed tomography (PET/CT) scan showed two hypermetabolic fluorodeoxyglucose- (FDG-) avid lesions involving the right diaphragmatic pleura. CT-guided needle-core biopsy was performed and histopathological examination showed neoplastic cells growing mainly in sheets with focal areas suggestive of vascular spaces lined by cytologically malignant epithelioid cells. Immunohistochemical analysis showed strong positivity for vimentin, CD31, CD68, and Fli-1 markers. The overall pathological and immunohistochemical features supported the diagnosis of epithelioid angiosarcoma. The patient was scheduled for surgery in three weeks. Unfortunately, the patient died after one week after discharge secondary to pulseless ventricular tachycardia arrest followed by asystole. Moreover, we also present a brief literature review on pleural angiosarcoma. PMID:23844302

Abu-Zaid, Ahmed; Mohammed, Shamayel

2013-01-01

186

[A 67-year old man with right arm paresthesias].  

PubMed

A 63-year-old man was admitted to the emergency room with chest pain. He had experienced a painful, tingling sensation in the right arm for the last three months, as well as pain in the right scapula. ECG and standard blood samples were normal. An X-ray of the thorax showed a mass in the superior sulcus on the right side. Further investigation with CT and MRI identified a large tumour, about 6 cm in size, with infiltrative growth involving the upper costae. Biopsy revealed a non-small cell carcinoma of the lung. The patient underwent a tri-modal treatment regimen with induction chemotherapy (two courses of cisplatin and etopside) and concomitant radiotherapy (50 Gy in 2 Gy fractions) before a right upper lobectomy was performed. 1 year after surgery the patient is alive, with no signs of recurrent or metastatic disease. Pancoast tumours are an infrequent subtype of lung cancers. Diagnostic delay is not uncommon. The peripheral location of the tumour generates symptoms that may easily be attributed to other causes, such as those of a musculoskeletal origin. Pre-operative chemo-radiotherapy has showed improved survival outcomes compared to pre-operative radiotherapy alone. PMID:20029558

Sagerup, Camilla M T; Brustugun, Odd Terje; Jørgensen, Lars

2009-12-17

187

Clinical Crossroads: A 45YearOld Man With Low Back Pain  

Microsoft Academic Search

To the Editor: The Clinical Crossroads1 about the 45-year-old attorney with low back pain was intriguing and brought out some of the diagnostic dilemmas in the practice of clinical medicine. The patient consulted an orthopedic surgeon who recom- mended lumbar laminectomy with spinal fusion. The patient then obtained consultation with a neurosurgeon who advised against surgery and recommended that the

Brian A. Davis

188

Chiropractic management of a 47-year-old firefighter with lumbar disk extrusion  

PubMed Central

Abstract Objective This case report describes the effect of exercise-based chiropractic treatment on chronic and intractable low back pain complicated by lumbar disk extrusion. Clinical Features A 47-year–old male firefighter experienced chronic, unresponsive low back pain. Pre- and posttreatment outcome analysis was performed on numeric (0-10) pain scale, functional rating index, and the low back pain Oswestry data. Secondary outcome assessments included a 1-rep maximum leg press, balancing times, push-ups and sit-ups the patient performed in 60 seconds, and radiographic analysis. Intervention and Outcome The patient was treated with Pettibon manipulative and rehabilitative techniques. At 4 weeks, spinal decompression therapy was incorporated. After 12 weeks of treatment, the patient's self-reported numeric pain scale had reduced from 6 to 1. There was also overall improvement in muscular strength, balance times, self-rated functional status, low back Oswestry scores, and lumbar lordosis using pre- and posttreatment radiographic information. Conclusion Comprehensive, exercise-based chiropractic management may contribute to an improvement of physical fitness and to restoration of function, and may be a protective factor for low back injury. This case suggests promising interventions with otherwise intractable low back pain using a multimodal chiropractic approach that includes isometric strengthening, neuromuscular reeducation, and lumbar spinal decompression therapy. PMID:19646377

Schwab, Matthew J.

2008-01-01

189

Communication and Your 13-to 18-Year-Old  

MedlinePLUS

... Free Health Lessons Social Media: Connect With Us Communication and Your 13- to 18-Year-Old KidsHealth > ... games, and talking about current events. Vocabulary and Communication Teens essentially communicate as adults, with increasing maturity ...

190

Complex Motor Learning in Four-Year-Olds  

ERIC Educational Resources Information Center

The effects of 4 months of gymnostic training upon complex and simple gross motor abilities and general cognitive and psychosocial functioning in 4-year-olds were compared with the effects of music training and no treatment. (WY)

Leithwood, K. A.; Fowler, W.

1971-01-01

191

Primary Mature Cyst?c Teratoma Mimick?ng an Adrenal Mass in an Adult Male Patient  

PubMed Central

Teratomas are bizarre neoplasms derived from embryonic tissues that are typically found only in the gonadal and sacrococcygeal regions of adults. Primary retroperitoneal teratomas are rare and present challenging management options. We report a case of a unilateral primary retroperitoneal mature cystic teratoma mimicking an adrenal mass in a 54-year-old male patient. Complete resection of the adrenal mass was performed by the flank approach by using the 11th rib resection. Because of the risk of malignancy, follow-up radiographic studies were performed to ensure the oncologic efficacy of resection. The patient has been free of recurrence for longer than 12 months. PMID:24578814

Ener, Kemal; Aldemir, Mustafa; Isik, Evren; Irkkan, Cigdem; Kayigil, Onder

2014-01-01

192

Primary mature cyst?c teratoma mimick?ng an adrenal mass in an adult male patient.  

PubMed

Teratomas are bizarre neoplasms derived from embryonic tissues that are typically found only in the gonadal and sacrococcygeal regions of adults. Primary retroperitoneal teratomas are rare and present challenging management options. We report a case of a unilateral primary retroperitoneal mature cystic teratoma mimicking an adrenal mass in a 54-year-old male patient. Complete resection of the adrenal mass was performed by the flank approach by using the 11th rib resection. Because of the risk of malignancy, follow-up radiographic studies were performed to ensure the oncologic efficacy of resection. The patient has been free of recurrence for longer than 12 months. PMID:24578814

Okulu, Emrah; Ener, Kemal; Aldemir, Mustafa; Isik, Evren; Irkkan, Cigdem; Kayigil, Onder

2014-02-01

193

A Spinal Arteriovenous Fistula in a 3-Year Old Boy  

PubMed Central

We present a case of a 3-year-old boy with neurodegeneration. Family history reveals Rendu-Osler-Weber disease. Magnetic resonance imaging (MRI) of the spinal cord and spinal angiography showed a spinal arteriovenous fistula with venous aneurysm, causing compression of the lumbar spinal cord. Embolisation of the fistula was executed, resulting in clinical improvement. A week after discharge he was readmitted with neurologic regression. A second MRI scan revealed an intraspinal epidural haematoma and increase in size of the aneurysm with several new arterial feeders leading to it. Coiling of the aneurysm and fistulas was performed. Postoperative, the spinal oedema increased despite corticoids, causing more extensive paraplegia of the lower limbs and a deterioration of his mental state. A laminectomy was performed and the aneurysm was surgically removed. Subsequently, the boy recovered gradually. A new MRI scan after two months showed less oedema and a split, partly affected spinal chord. This case shows the importance of excluding possible arteriovenous malformations in a child presenting with progressive neurodegeneration. In particular when there is a family history for Rendu-Osler-Weber disease, scans should be performed instantly to rule out this possibility. The case also highlights the possibility of good recovery of paraplegia in paediatric Rendu-Osler-Weber patients. PMID:24707424

Crijnen, Thomas E. M.; Voormolen, Maurits H. J.; Robert, Dominique; Jorens, Philippe G.; Ramet, Jose

2014-01-01

194

Development of a sex education programme for 12?year?old to 14?year?old Turkish adolescents  

Microsoft Academic Search

Previous research has documented a need for the development of a sex education programme in Turkish schools in terms of adolescence readiness and the presence of misconceptions regarding critical aspects of sexual issues. Currently no school?based sex education is available for Turkish adolescents. This paper presents the development of a contemporary sex education programme for 12?year?old to 14?year?old adolescents, entitled

Figen Cok; Lizbeth Ann Gray

2007-01-01

195

A 62YearOld Man Presenting with Shortness of Breath for 6 Months  

Microsoft Academic Search

62-year-old man with no significant past medi- cal history presented to the emergency depart- ment with a chief complaint of shortness of breath for 6 months. The patient stated that at baseline he expe- rienced shortness of breath after walking approximately 100 feet, but that this progressively worsened over the course of six months until the morning of presentation when

Bryan DiBuono; Mark Wegmann; Jeevan J. Pai; Rebecca A. F. Murray; Erick Blaudeau; Fred A. Lopez

2005-01-01

196

A novel case of chronic conjunctivitis in a 58-year-old woman caused by Raoultella.  

PubMed

A 58-year-old woman presented to eye emergency with a chronic conjunctivitis which was diagnosed by laboratory microbiological testing to be due to the environmental pathogen Raoultella planticola. The organism was sensitive to Chloramphenicol and the patient made a rapid recovery on these drops. This is the first report of this organism infecting the eye. PMID:24865691

Zuberbuhler, B; Abedin, A; Roudsari, A

2014-10-01

197

Severe mitral valve regurgitation in a 23-year-old man.  

PubMed

Early surgical repair of severe mitral valve regurgitation in symptomatic and asymptomatic patients is associated with better long-term outcomes than watchful waiting. This article describes an asymptomatic, 23-year-old man whose significant cardiac murmur (later confirmed to be mitral regurgitation) was found during a routine examination for a prescription refill of an antiviral drug. PMID:25343433

Guerra, Michael

2014-11-01

198

Oral Health and Treatment Needs among 18YearOld Iranians  

Microsoft Academic Search

Objective: To investigate the oral health status of 18-year-old Iranians in relation to their gender, place of residence and level of education. Subjects and Methods: Thirty-three calibrated examiners in 2002 collected data as part of a national survey, according to World Health Organization criteria for sampling and clinical diagnoses, across 28 provinces. The study sample was 4,448; male: 2,021 and

Hossein Hessari; Miira M. Vehkalahti; Mohammad J. Eghbal; Hamid Samadzadeh; Heikki T. Murtomaa

2008-01-01

199

Development and health of 5 - 8-year-old singletons born after intracytoplasmic sperm injection  

Microsoft Academic Search

This thesis describes the Leiden Artificial Reproductive Techniques Follow-up Project. In this project, the potential long-term effects of intracytoplasmic sperm injection (ICSI) were assessed in 5 – 8-year-old singleton children. ICSI is the method of artificial reproduction in which a sperm cel is injected into an oocyte using a microinjection pipette. The technique is mainly successful in overcoming male factor

Marjolein Knoester

2007-01-01

200

Decreased melatonin secretion in a phenotypically male 46,XX patient with classic 21-hydroxylase deficiency.  

PubMed

The possible role of gonadal steroids and gonadotropins in regulating melatonin secretion has been suggested in clinical syndromes of the hypothalamic-pituitary-gonadal axis. We describe the results of melatonin secretion in a 37-year old male patient who presented with azoospermia. The patient was an XX male, had classic simple virilizing form of 21-hydroxylase deficiency, which led to a masculine phenotype. He was ovariectomized at the age of three years and reared as a male. Melatonin production (aMT6s) was determined at baseline and during 12 months of replacement therapy. Results were compared with those obtained in age-matched male controls. Pretreatment aMT6s values were decreased (14.3 microg/24 h vs. 29.0+/-5.5 in controls). Dexamethasone replacement was associated with an increase in aMT6s values (19.3-20.9 microg/24 h). The addition of testosterone to dexamethasone replacement resulted in normalization of aMT6s (27.6-33.1 microg/24 h) and serum 17OH progesterone, testosterone and estradiol levels. The present data indicate that androgen excess due to 21 hydroxylase deficiency is associated with decreased melatonin secretion. These results support the hypothesis that sex steroids modulate melatonin secretion. PMID:10926323

Luboshitzky, R; Qupti, G; Shen-Orr, Z; Hardoff, R

2000-01-01

201

"Generalist Genes" and Mathematics in 7-Year-Old Twins  

ERIC Educational Resources Information Center

Mathematics performance at 7 years as assessed by teachers using UK national curriculum criteria has been found to be highly heritable. For almost 3000 pairs of 7-year-old same-sex twins, we used multivariate genetic analysis to investigate the extent to which these genetic effects on mathematics performance overlap with genetic effects on reading…

Kovas, Y.; Harlaar, N.; Petrill, S. A.; Plomin, R.

2005-01-01

202

Balancing on a Slackline: 8-Year-Olds vs. Adults  

PubMed Central

Children are less stable than adults during static upright stance. We investigated whether the same holds true for a task that was novel for both children and adults and highly dynamic: single-legged stance on a slackline. We compared 8-year-olds with young adults and assessed the following outcome measures: time on the slackline, stability on the slackline (calculated from slackline reaction force), gaze movement, head-in-space rotation and translation, trunk-in-space rotation, and head-on-trunk rotation. Eight-year-olds fell off the slackline quicker and were generally less stable on the slackline than adults. Eight-year-olds also showed more head-in-space rotation and translation, and more gaze variability around a visual anchor point they were instructed to fixate. Trunk-in-space and head-on-trunk rotations did not differ between groups. The results imply that the lower postural stability of 8-year-olds compared to adults – as found in simple upright stance – holds true for dynamic, novel tasks in which adults lack the advantage of more practice. They also suggest that the lack of head and gaze stability constitutes an important limiting factor in children’s ability to master such tasks. PMID:23626583

Schärli, Andrea Melanie; Keller, Melanie; Lorenzetti, Silvio; Murer, Kurt; van de Langenberg, Rolf

2013-01-01

203

The Passive in 3- and 4-Year-Olds  

ERIC Educational Resources Information Center

This paper argues that analyzing the patterns of individual subject performance in tests of comprehension of passives might give insight into how little children interpret passives: 3 and 4 year-olds seem to go through a range of passive interpretation, that varies from actual comprehension to total non-comprehension. The fact that some small…

de Barros Pereira Rubin, Maraci Coelho

2009-01-01

204

Five and Six-Year Olds' Views of Friendship.  

ERIC Educational Resources Information Center

Reports on a study of views of friendship among 20 5- and 6-year-old British students. Finds that boys and girls were able to interpret friendships as transactions. Also finds differences between boys and girls on their understanding of "bad friends." (CFR)

Craft, Anna

1994-01-01

205

A 54-year-old woman with degenerative back pain  

Microsoft Academic Search

Back pain is a common symptom: up to 70% of UK adults experience this symptom by the age of 60 and most have moderate to severe pain. Back pain accounted for 12% of consultations to traditional acupuncturists in 2001 and is one of the most common reasons for consultation with an acupuncturist. This case report concerns a 54-year-old woman with

Claire M Tuck

2010-01-01

206

Service Organization for Four Year Old Children with Auditory Handicaps.  

ERIC Educational Resources Information Center

An oral program for four-year-old children with hearing impairments features teamwork among direct interventionists (teacher, speech therapist, audiologist, psychologist, social workers, and parents) on rehabilitative speech therapy activities as well as integration of hearing with hearing impaired children. (CL)

Morrow-Lettre, Christiane

1984-01-01

207

Measurement of Temperament in One to Three Year Old Children.  

ERIC Educational Resources Information Center

This study was designed to (1) gather Australian data on the Toddler Temperament Scale (TTS), (2) assess age differences on temperament in the one- to three-year-old group; (3) assess the psychometric properties of the TTS; and (4) consider some issues of concurrent validity in the measurement of temperament and behavioral adjustment. (Author)

Prior, Margot; And Others

1987-01-01

208

Localized secondary erythromelalgia in an 11-year-old boy.  

PubMed

We report an 11-year-old boy with localized secondary erythromelalgia on his left medial thigh. The episodes responded well to indomethacin and prednisone but recurred after the medications were stopped. The disease was stable after being treated for 5 months. PMID:22612394

Wu, Hui-Hui; Wang, Ming-Jun; Luo, Di-Qing; Lin, Qing

2013-01-01

209

Oral Health among 35- to 44YearOld Iranians  

Microsoft Academic Search

Objective: To investigate the oral health status of 35- to 44-year-old Iranians in relation to gender, place of residence and education. Subjects and Methods: In 2002, data (n = 8,301) were collected as part of a national survey using WHO criteria for sampling and clinical diagnoses across 28 provinces by 33 calibrated examiners who performed examinations under a dental light

Hossein Hessari; Miira M. Vehkalahti; Mohammad J. Eghbal; Heikki T. Murtomaa

2007-01-01

210

Concepts of Romance in 15-Year-Old Adolescents.  

ERIC Educational Resources Information Center

Examined 15-year olds' descriptions of dating partners and romance. Dating experiences were brief in duration, though intense in frequency of contact. Affiliative qualities more than attachment qualities characterized their conscious views of romance. Girls were more likely than boys to mention interpersonal qualities, while boys were more likely…

Feiring, Candice

1996-01-01

211

A Three Year Old Learning Literacy at Home  

Microsoft Academic Search

This study provides a record of one day of literacy learning at home of a three year old child. It indicates the wide variety of literacy activities which a young child explores and often initiates. The importance of story readings as well as repeated readings of the same book are noted. However, the use of other print at home, songs

Robin Campbell

1998-01-01

212

20-year-old injury: an unusual cause of stroke.  

PubMed

A 62-year-old man presented with a 2-day history of headache, nausea and dizziness on a background of recently diagnosed stage 2c prostate carcinoma and controlled hypertension. Imaging confirmed bilateral cerebellar strokes; on further investigations, he was found to have undiagnosed subclavian steal syndrome following severe injury to his left arm more than 20 years earlier. PMID:23606391

Lim, V W L; Flynn, C A; O'Connor, M; Lyons, D

2013-01-01

213

Repetitive Behaviours in Typically Developing 2-Year-Olds  

ERIC Educational Resources Information Center

Background: Repetitive behaviours are an essential part of the diagnosis of autism but are also commonly seen in typically developing children. The current study investigated the frequency and factor structure of repetitive behaviours in a large community sample of 2-year-olds. Methods: A new measure, the Repetitive Behaviour Questionnaire (RBQ-2)…

Leekam, Susan; Tandos, Jonathan; McConachie, Helen; Meins, Elizabeth; Parkinson, Kathryn; Wright, Charlotte; Turner, Michelle; Arnott, Bronia; Vittorini, Lucia; Le Couteur, Ann

2007-01-01

214

Grammatical Morpheme Production in 4-Year-Old Children.  

ERIC Educational Resources Information Center

Grammatical morpheme (GM) production was studied in 15-minute spontaneous language samples from 100 4-year-olds. Substantial variability was observed in both the frequency of obligatory contexts and in the percentages of correct usage of GM. For only one morpheme did all 100 participants contain the minimum number of 3 obligatory contexts.…

Balason, Denise V.; Dollaghan, Christine A.

2002-01-01

215

A 42-year-old man with “pseudo-coprolalia”  

Microsoft Academic Search

A 42-year-old right-handed man presented with one week’s history of uncharacteristic use of coarse language with associated anomia, inappropriate word usage and slowness of thoughts. Imaging demonstrated a solitary infarct involving the anterior left thalamus. Clinical and imaging findings and the current literature on anterior thalamic insult are discussed.

A. Chiu; W. McAuliffe

2010-01-01

216

The Structure of Executive Function in 3-Year-Olds  

ERIC Educational Resources Information Center

Although the structure of executive function (EF) during adulthood is characterized by both unity and diversity, recent evidence suggests that preschool EF may be best described by a single factor. The latent structure of EF was examined in 228 3-year-olds using confirmatory factor analysis. Children completed a battery of executive tasks that…

Wiebe, Sandra A.; Sheffield, Tiffany; Nelson, Jennifer Mize; Clark, Caron A. C.; Chevalier, Nicolas; Espy, Kimberly Andrews

2011-01-01

217

A 54-year-old man referred with nonresolving pneumonia.  

PubMed

A 54-year-old man was referred with nonresolving pneumonia. He had been treated for community-acquired pneumonia 6 weeks earlier. He reported grade 2 dyspnea, malaise, and a nonproductive cough. He had also experienced three episodes of minimal hemoptysis but denied weight loss, fever, or any other constitutional symptoms. He was a nonsmoker and was being treated for dyslipidemia. PMID:25180750

Catteeuw, Julie; Koegelenberg, Coenraad F N; Bruwer, Johannes W; Sissolak, Gerhard; Schroeter, Leocardea; Mohamed, Nooroudien; Irusen, Elvis M

2014-09-01

218

How Do Korean Nine Year Olds Make Historical Inferences?  

ERIC Educational Resources Information Center

This study explores how a group of nine year olds in Korea form historical inferences using pictures of historical paintings. It investigates whether they have the ability to form plausible inferences about the lives of people depicted in these pictures, what they can infer about the lives of people depicted in the pictures using prior knowledge,…

Kang, Sunjoo

2010-01-01

219

Two-Year-Olds Compute Syntactic Structure On-Line  

ERIC Educational Resources Information Center

Syntax allows human beings to build an infinite number of new sentences from a finite stock of words. Because toddlers typically utter only one or two words at a time, they have been thought to have no syntax. Using event-related potentials (ERPs), we demonstrated that 2-year-olds do compute syntactic structure when listening to spoken sentences.…

Bernal, Savita; Dehaene-Lambertz, Ghislaine; Millotte, Severine; Christophe, Anne

2010-01-01

220

Allograft Reconstruction After Sarcoma Resection in Children Younger Than 10 Years Old  

Microsoft Academic Search

Preservation of limb function in pediatric oncology patients is challenging with the ongoing growth of limbs contralateral\\u000a to reconstructed limbs. We analyzed 22 patients younger than 10 years old who received an allograft after resection of a bone\\u000a sarcoma with a minimum followup of 2 years (mean, 4 years; range, 2–14 years). The mean age was 7 years (range, 2–10 years).\\u000a There were 16 boys and

D. Luis Muscolo; Miguel A. Ayerza; Luis Aponte-Tinao; German Farfalli

2008-01-01

221

Gender, Popularity and Notions of In/Authenticity amongst 12-Year-Old to 13-Year-Old School Girls  

ERIC Educational Resources Information Center

This paper draws on data from a research project investigating gendered identities and interactions of high-achieving students in Year Eight in England (12-13 years old), particularly in relation to students' "popularity" amongst their peers. As part of this study 71 students were interviewed from nine different schools in urban, rural and small…

Read, Barbara; Francis, Becky; Skelton, Christine

2011-01-01

222

Gender, popularity and notions of in\\/authenticity amongst 12?year?old to 13?year?old school girls  

Microsoft Academic Search

This paper draws on data from a research project investigating gendered identities and interactions of high?achieving students in Year Eight in England (12–13 years old), particularly in relation to students’ ‘popularity’ amongst their peers. As part of this study 71 students were interviewed from nine different schools in urban, rural and small town locations. From an analysis of participants’ conceptions

Barbara Read; Becky Francis; Christine Skelton

2011-01-01

223

Internet Use and Psychological Well-Being among 10-Year-Old and 11-Year-Old Children  

ERIC Educational Resources Information Center

This paper uses data from the 2009 Kids' Life and Times Survey, involving 3657 children aged 10 or 11 years old in Northern Ireland. The survey indicated high levels of use of Internet applications, including social-networking sites and online games. Using the KIDSCREEN-27 instrument, the data indicate that the use of social-networking sites and…

Devine, Paula; Lloyd, Katrina

2012-01-01

224

Poor Stroop performances in 15-year-old dyslexic teenagers  

Microsoft Academic Search

The Stroop test enables interference between color naming and reading to be studied. Protopapas et al. (2007) reported more errors in an interference task and longer reaction times in 12.5-year-old dyslexics; also more Stroop interference\\u000a with lower reading skills. The present study uses a version of the Stroop with four color cards and aims to test interference\\u000a and flexibility in

Zoï Kapoula; Thanh-Thuan Lê; Audrey Bonnet; Pauline Bourtoire; Emilie Demule; Caroline Fauvel; Catherine Quilicci; Qing Yang

2010-01-01

225

Dietary Habits of Welsh 12-13 Year Olds  

ERIC Educational Resources Information Center

This study examined the dietary habits of Welsh 12-13 year olds. A cohort of 84 boys and 81 girls, age 12.9 SD 0.3 years; body mass 51.3 SD 12.6kg; and stature 1.54 SD 0.08m, completed a food frequency questionnaire and seven-day food diary. Mean daily kilocalories (kcal/d), and percentages of total fat, saturated fat, carbohydrate, and protein,…

Thomas, Non-Eleri; Cooper, Stephen-Mark; Graham, Mike; Boobier, Wyndham; Baker, Julien; Davies, Bruce

2007-01-01

226

Clock time in seven to ten year-old children  

Microsoft Academic Search

The present research aimed to study how children identify and produce various types of clock time on pictures of analogue\\u000a display and whether the use of digital watches makes a difference in their performance on the identification and production\\u000a tasks. Over one hundred (129) 7–10 year-old children of both sexes were tested under two different conditions. In the first\\u000a condition

Mary Vakali

1991-01-01

227

Caries Prevalence in 2.5YearOld Children  

Microsoft Academic Search

The prevalence of caries and gingivitis was determined clinically in 2.5-year-old children (n = 832) living in the southern suburbs of Stockholm. The occurence of mutans streptococci and lactobacilli was determined in samples taken from the tongue and the buffer capacity of the saliva was measured. The parents answered a structured questionnaire concerning their children’s dietary habits, oral hygiene, fluoride

M. Grindefjord; G. Dahllöf; G. Ekström; B. Höjer; T. Modéer

1993-01-01

228

Chemical properties of two-year-old deciduous species  

Microsoft Academic Search

Contents of ash, hot-water extractives, 1% sodium hydroxide extractives, alcohol-benzene extractive, lignin, holocellulose, alpha-cellulose, and pentosan were determined on two-year-old, short-rotation trees of autumn olive, black alder, black locust, eastern cottonwood, royal paulownia, silver maple, and sycamore. These plantations were established in 1978 on marginal agricultural land that was not suitable for food production in Illinois. Six comparable species of

P. Chow; G. L. Rolfe; C. S. Lee; T. A. White

1983-01-01

229

Electroconvulsive Therapy use in a 97YearOld Woman  

Microsoft Academic Search

Objectives: The aim of this paper is to report the use of electroconvulsive therapy (ECT) to successfully treat depression in a 97-year-old woman, and to discuss the safety and efficacy of ECT in the very old.Methods: A case report and review of the literature on the use of ECT to treat depression in the very old is presented.Results: The subject

David Burke; Joanne Shannon; Alexander Beveridge

2007-01-01

230

Treatment of a four-year-old victim of incest  

Microsoft Academic Search

A case study describing the use of behavior techniques in the treatment of a four—year—old sexual assault victim is presented. The target behaviors included eating, phobic behaviors, self—injurious behaviors, and comments made about the father (the perpetrator) and the paternal grandmother. The child's mother served as both data collector and therapist. The study demonstrates that child victims can experience a

Judith V. Becker; Linda J. Skinner; Gene G. Abel

1982-01-01

231

Cosmetic Clitoridectomy in a 33YearOld Woman  

Microsoft Academic Search

The Female Genital Mutilation Act (2003) in England allows for mental health exceptions for cosmetic surgery resulting from\\u000a perceived abnormality. Similar legislation exists in other countries. There are no reported cases of clitoridectomy for cosmetic\\u000a reasons or any discussion in the literature of mental health exceptions to the Act. This is a single case report on a 33-year-old\\u000a married, heterosexual

David Veale; Joe Daniels

232

Germination of 151-year old Acacia spp. seeds  

Microsoft Academic Search

A collection of seeds from five Acacia species was made in Egypt in 1856. Since then, the seeds have been stored at room temperature in different Swedish museums.\\u000a Due to the extreme longevity within the seeds of Acacia and related species, germination tests were performed on the now 151-year old seed. Seeds of two of the five species tested\\u000a germinated.

Matti W. Leino; Johan Edqvist

2010-01-01

233

Heart Health...Your Choice. 11-14 Year Olds.  

ERIC Educational Resources Information Center

The purpose of this illustrated booklet is to teach 11-14 year old students that all healthy Americans, 2 years of age or older, should eat in a way that is low in saturated fat and cholesterol to help reduce the risk of heart disease. The guide is designed to promote changes in eating patterns, to show children how to switch to good eating…

National Heart, Lung, and Blood Inst. (DHHS/NIH), Bethesda, MD.

234

Giant aneurysm of the basilar artery in an 86 year old woman  

PubMed Central

In this article we present an 80 year old female patient with an unruptured giant aneurysm of the basilar artery presenting with posterior circulation ischemic symptoms. Angiography and CT revealed giant basilar aneurysmal dilatation with severe and wide intracranial arteriosclerosis. We described the uniqueness of this case. Giant basilar aneurysm is associated with various complications particularly brain stem infarction. It is emphasized that arteriosclerosis plays an important role in the formation of giant basilar aneurysms. PMID:24358886

Yu, Yong peng

2013-01-01

235

Diaphragmatic hernia in an 8-year-old with Ehlers-Danlos syndrome  

Microsoft Academic Search

Ehlers-Danlos syndrome (EDS) includes a group of connective-tissue disorders characterized by abnormal collagen metabolism.\\u000a The diverse spectrum of this disease and its complications present a distinct challenge to the surgeon. Patients with this\\u000a hereditary disorder may have hyperelastic or fragile skin, poor wound healing, hypermobile joints, clotting abnormalities,\\u000a spontaneous pneumothoraces, recurrent hernias, bowel perforation, and vascular complications. An 8-year-old female

J. L. Iglesias; T. Renard

1998-01-01

236

Renal Cell Carcinoma in a 3 year-old Girl: a case report  

Microsoft Academic Search

A 3-year-old girl presented with vomiting for two days. Abdominal ultrasonogram revealed a mass at the lower pole of left kidney. Non-contrast enhanced abdominal computed tomography(CT) scan revealed high attenuation of the tumor and calcified lymphadenopathies in the retroperito - neum. On a contrast-enhanced CT scan, the mass was enhanced heterogenously. The patient under - went left radical nephrectomy and

Fei-Shih Ya ng; Shin-Lin Shih; Chung Shan

2008-01-01

237

Pathology Case Study: A 45-Year-Old Female with Acute Liver Failure  

NSDL National Science Digital Library

The University of Pittsburgh School of Medicine's Department of Pathology has compiled a series of case studies to help both students and instructors. In this particular study a 45-year-old female patient is suffering from acute liver failure. The case study provides test results and images along with microscopic photos and description. Clicking on the final diagnosis provides a thorough explanation of the diagnosis and treatment.

Richert, Charles A.

2007-08-11

238

Case 6-2003: A Nine-Year-Old Girl with Progressive Weakness and Areflexia  

Microsoft Academic Search

A nine-year-old right-handed girl from the United Arab Emirates was admitted to the hospital because of progressive weakness and areflexia. The patient had been well until three months earlier, when a gait difficulty developed. A physician diagnosed a vitamin deficiency, and treatment was instituted but without benefit. One month later, progressive weakness and a slapping gait developed; she was unable

Howard W. Sander; E. Tessa Hedley-Whyte

2010-01-01

239

Membranous nephropathy associated with familial chronic ulcerative colitis in a 12-year-old girl  

Microsoft Academic Search

Glomerulonephritis is a rare complication in patients with inflammatory bowel disease. We report a case of membranous nephropathy (MN) in a 12.6-year-old girl with chronic ulcerative colitis. The girl was referred to the hospital with bloody diarrhea and arthralgia. Routine urinalysis showed 1 g\\/m2 protein excretion in 24 h. Serum ANCA titers were positive. The diagnoses were confirmed by coloscopy and kidney

Regina M. Ridder; Hans W. Kreth; Eva Kiss; Hermann J. Gröne; Nader Gordjani

2005-01-01

240

Ascites associated with uterine leiomyoma in a 22-year-old woman with systemic lupus erythematosus.  

PubMed

Ascites in systemic lupus erythematosus (SLE) patients has a variety of etiologies, which usually require different treatment options. Our case was a 22-year-old patient with an unusual combination of ascites, uterine leiomyoma and SLE. The patient presented with painless ascites of an inflammatory nature. However, the ascites was not related to peritonitis and SLE disease activity. The ascites disappeared following laparotomy and tumor resection without additional medication. Gynecologic benign tumors including uterine leiomyoma can be the cause of ascites in SLE patients. Clinicians should be aware of that possibility in case painless ascites occurs in females with SLE. PMID:24972898

Seo, M R; Sung, J Y; Cho, H J; Ryu, H J; Choi, H-J; Park, C-Y; Baek, H J

2014-10-01

241

Lymph node metastasis in gastric cardiac adenocarcinoma in male patients  

PubMed Central

AIM: To reveal the clinicopathological features and risk factors for lymph node metastases in gastric cardiac adenocarcinoma of male patients. METHODS: We retrospective reviewed a total of 146 male and female patients with gastric cardiac adenocarcinoma who had undergone curative gastrectomy with lymphadenectomy in the Department of Surgery, Xin Hua Hospital and Rui Jin Hospital of Shanghai Jiaotong University Medical School between November 2001 and May 2012. Both the surgical procedure and extent of lymph node dissection were based on the recommendations of Japanese gastric cancer treatment guidelines. Univariate and multivariate analyses of lymph node metastases and the clinicopathological features were undertaken. RESULTS: The rate of lymph node metastases in male patients with gastric cardiac adenocarcinoma was 72.1%. Univariate analysis showed an obvious correlation between lymph node metastases and tumor size, gross appearance, differentiation, pathological tumor depth, and lymphatic invasion in male patients. Multivariate logistic regression analysis revealed that tumor differentiation and pathological tumor depth were the independent risk factors for lymph node metastases in male patients. There was an obvious relationship between lymph node metastases and tumor size, gross appearance, differentiation, pathological tumor depth, lymphatic invasion at pN1 and pN2, and nerve invasion at pN3 in male patients. There were no significant differences in clinicopathological features or lymph node metastases between female and male patients. CONCLUSION: Tumor differentiation and tumor depth were risk factors for lymph node metastases in male patients with gastric cardiac adenocarcinoma and should be considered when choosing surgery. PMID:24115823

Ren, Gang; Chen, Ying-Wei; Cai, Rong; Zhang, Wen-Jie; Wu, Xiang-Ru; Jin, Ye-Ning

2013-01-01

242

A 39-year-old man with dyspnoea, low forced expiratory volume and a large mass of the left hemithorax  

PubMed Central

In patients with intrathoracic neoplasms, low forced expiratory volume (FEV1) can preclude surgical treatment. Here, we present a case of a giant solitary fibroma of the pleura (SFTP) successfully treated by surgical removal in spite of low FEV1. A 39-year-old male patient was referred to our hospital with dyspnoea and chest distress. Computed tomography (CT) showed a large mass in the left chest. Spirometry showed FEV1 1.4 L (39% of the expected value). Computed tomography scan-guided transcutaneous aspiration biopsy was performed on the patient, and microscopic examination of the specimen revealed spindle tumor cells with a background of abundant collagen. Complete surgical resection was accomplished. The tumor was large and encapsulated. It measured 28 cm × 20 cm × 18 cm. The definitive diagnosis obtained by histopathology after resection was benign SFTP. The patient felt no dyspnoea at discharge. Surgical treatment of SFTP should be considered even in patients with a huge tumor and with increased post-operative risk. PMID:24596524

Sun, Zhi-Gang; Liu, Xiang-Yan; Shan, Bao-Zhong; Zhang, Min; Li, Zhe

2013-01-01

243

75 FR 76636 - Anthropomorphic Test Devices; Hybrid III 6-Year-Old Child Test Dummy, Hybrid III 6-Year-Old...  

Federal Register 2010, 2011, 2012, 2013

...Anthropomorphic Test Devices; Hybrid III 6-Year-Old Child Test Dummy, Hybrid III 6-Year-Old Weighted Child Test Dummy AGENCY: National Highway Traffic...specifications for the Hybrid III six-year-old child dummy, and the Hybrid III...

2010-12-09

244

Bronchopulmonary sequestration in a 60 year old man.  

PubMed

We report a case of bronchopulmonary sequestration (BPS) in a 60 year old man with recurrent cough. After failed antibiotic therapy for presumed left lower lobe (LLL) pneumonia seen on chest radiographs, bronchoscopy was performed revealing cryptogenic organizing pneumonia. Further work-up with thoracic imaging demonstrates a feeding artery from the thoracic aorta to the LLL consolidation indicating the presence of BPS. A brief review of the clinical and radiological features and management options of BPS are listed, with particular emphasis on the various imaging modalities and techniques in the diagnosis and pre-surgical planning of intralobar sequestration. PMID:25426223

Naffaa, Lena; Tank, Jay; Ali, Sara; Ong, Cesar

2014-10-01

245

[Torsion of a hydrosalpinx in a 14-year old].  

PubMed

Lower abdominal pain in women often gives rise to diagnostic problems. We had a 14-year-old girl suffering from acute lower abdominal pain without effect of painkillers. Ultrasound revealed a cystic process in the pelvis. At laparoscopy we saw a right-sided hydrosalpinx with torsion. The hydrosalpinx was removed and afterwards she had no pain. Torsion of a hydrosalpinx is a very rare condition. It is very important that adnexal torsion is diagnosed and treated promptly in order to save the reproductive organs and prevent further complications. PMID:18940159

Sørensen, Rikke Korsgaard

2008-10-01

246

Spontaneous intratesticular hemorrhage in a 15-year-old boy.  

PubMed

Spontaneous testicular hemorrhage is a very rare pathology, especially in children. We report an interesting case of spontaneous testicular hemorrhage in a 15-year-old boy. There were no associated constitutional symptoms and no history of trauma, infection, or bleeding disorders. Tumor markers, hemogram parameters, and biochemical tests were normal. At scrotal exploration, there was no evidence of testicular torsion or any other pathology. A scrotal orchiectomy was performed. The main histopathological findings were diffuse hematoma, interstitial hemorrhage, and coagulative necrosis. The synchronized evaluation of clinical and ultrasonographic findings and an appropriate histopathological evaluation can usually diagnose this rare pathology. PMID:21459415

Yuksel, Mehmet Bilgehan; Altok, Muammer; Sayg?n, Ismail; Ciloglu, Murat

2011-10-01

247

A five years old girl child with Takayasu arteritis.  

PubMed

Takayasu arteritis is a systemic vasulitis of large vessels that mainly involves the aorta and its branches. It normally presents in third decade of life and has rarely been reported in children under 10 years of age. We report here a case of Takayasu arteritis in a 5 years old girl who presented with headache, generalized body swelling, severe hypertension, proteinuria and minimal functioning kidneys. Conventional angiography demonstrated narrowing of descending aorta, right subclavian artery and right common iliac artery. She responded steroids, diuretics, antiplatelets and digoxin and discharged home on maintenance therapy. PMID:24304997

Mahmud, Shahid; Ul Hassan Shah, Syed Awais; Zaman, Syed Qamar; Ali, Salman

2013-12-01

248

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

NASA Administrator Dan Goldin (left) shares a light moment during his meeting with 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. Behind Goldin is astronaut Doug Wheelock; behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

2000-01-01

249

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

NASA Administrator Dan Goldin (left) shares a laugh with VIP 10- year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. Behind Goldin is astronaut Doug Wheelock; behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS- 99.

2000-01-01

250

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

NASA Administrator Dan Goldin (left) listens intently to 10-year- old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. Behind Goldin is astronaut Doug Wheelock; behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS- 99.

2000-01-01

251

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

Ten-year-old Jonathan Pierce (second from right), who is garbed in a protective cooling suit, without the helmet, which was designed by NASA, poses with (left to right) NASA Administrator Dan Goldin, Mrs. Goldin, and astronaut Doug Wheelock. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS- 99.

2000-01-01

252

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

NASA Administrator Dan Goldin (left) watches as 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA, shakes hands with astronaut Dog Wheelock. Behind Jonathan is his mother, Penny. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

2000-01-01

253

Clinical, histologic, and genetic features of mesothelioma in a 7-year-old child.  

PubMed

Malignant mesothelioma (MM) is a highly aggressive malignancy that is extremely rare in children. This case report documents a 7-year-old male without previous asbestos exposure with peritoneal MM that initially responded to chemotherapy with cisplatin and gemcitabine but ultimately metastasized to his chest. He was diagnosed with MM based on histology, extensive immunohistochemical analyses, and an elevated serum CA-125 level. Cytogenetics and comparative genomic hybridization (CGH) analysis of his tumor identified a single extra copy number of chromosome 11 with few other changes noted. PMID:22961710

Sugalski, Aaron; Davis, Mary; Prasannan, Latha; Saldivar, Victor; Hung, Jaclyn Y; Tomlinson, Gail E

2013-01-01

254

Fournier's Gangrene in a Two Year Old Child: A Case Report  

PubMed Central

Necrotizing fasciitis of the perineum and external genitalia is a life-threatening infective gangrene, primarily seen in adults. It may be seen at any age but it is relatively uncommon in children. Here, we report a case of Fournier’s gangrene in a two year old male child who was treated aggressively with broad spectrum antibiotics and early surgical debridement with hemodynamic stabilization. Even though no obvious precipitating cause was identified, hygiene was thought to be the inciting factor. Early surgical debridement with appropriate antibiotics and aggressive supportive care gave good results. PMID:25302233

Bains, Satinder Pal Singh; Singh, Vikram; Jain, Amit; Arry, Vivek

2014-01-01

255

Fournier's Gangrene in a Two Year Old Child: A Case Report.  

PubMed

Necrotizing fasciitis of the perineum and external genitalia is a life-threatening infective gangrene, primarily seen in adults. It may be seen at any age but it is relatively uncommon in children. Here, we report a case of Fournier's gangrene in a two year old male child who was treated aggressively with broad spectrum antibiotics and early surgical debridement with hemodynamic stabilization. Even though no obvious precipitating cause was identified, hygiene was thought to be the inciting factor. Early surgical debridement with appropriate antibiotics and aggressive supportive care gave good results. PMID:25302233

Bains, Satinder Pal Singh; Singh, Vikram; Gill, Manmeet Kaur; Jain, Amit; Arry, Vivek

2014-08-01

256

Spontaneous midlobar lung lobe torsion in a 2-year-old Newfoundland.  

PubMed

A 2-year-old, intact male Newfoundland was presented for evaluation of a 1- to 2-day history of coughing, retching, and progressive lethargy. Thoracic radiographs demonstrated right-sided pleural effusion and lobar vesicular emphysema. An exploratory thoracotomy revealed midlobar torsion of the right caudal lung lobe. A partial lung lobectomy was performed, and following surgery, the dog recovered without complications. Lung lobe torsions in dogs typically occur at the hilus of the affected lung lobe. This report documents that midlobar lung lobe torsions occur in dogs and should be considered as a differential diagnosis in cases of lobar vesicular emphysema and pleural effusion. PMID:15131103

Hofeling, Andrew D; Jackson, Andrew H; Alsup, Joel C; O'Keefe, Debi

2004-01-01

257

Dirofilariasis in a 22-year-old airman deployed to the Mediterranean.  

PubMed

A 22-year-old male U.S. Navy airman with new nontender subcutaneous, 4-cm mass inferior to the right anterior costal margin was sent for routine biopsy. Sudden appearance of axillary lymph nodes prompted immediate excisional biopsy of the primary mass. Pathological evaluation was initially read as Onchocerca volvulus, the filarial nematode classically responsible for river blindness. Subsequent evaluation by Armed Forces Institute of Pathology resulted in a change of diagnosis to Dirofilaria species, not pathogenic in humans. The author discusses the literature of Dirofilaria infestations in humans, and how they may affect U.S. servicemen and women traveling to endemic areas. PMID:21987970

Udall, Don N

2011-09-01

258

Orthodontic Findings in 4- to 6-year-old Kindergarten Children from Southwest Germany  

Microsoft Academic Search

\\u000a Abstract\\u000a \\u000a \\u000a Objective:\\u000a   The objective of this epidemiologic study was to make basic data available on the age dependence of malocclusions and their\\u000a developmental tendency in 4- to 6-year-old kindergarten children so as to define the optimum time to start early treatment.\\u000a \\u000a \\u000a \\u000a \\u000a \\u000a Materials and Methods:\\u000a   In this study 2015 kindergarten children (1048 male, 967 female) aged between 4 and 6 years

Mirjam Berneburg; Claudia Zeyher; Till Merkle; Matthias Möller; Edgar Schaupp; Gernot Göz

2010-01-01

259

[Acute jaw-thoracic pain and syncope in a 41-year-old man].  

PubMed

A 41-year-old physically active man with no significant past medical history presented with sudden thoracic pain. The patient was referred to the next tertiary care hospital. A CT scan showed an ectasia of the ascending aorta with irregularities of the aortic wall without dissection. Despite initial refusal, the patient was referred to a university hospital with experience in aortic surgery. A triphase ECG-synchronized cardiothoracic flash protocol performed on a 256 line CT scanner confirmed an aortic intramural hematoma and a covered aortic perforation. Shortly afterwards the patient collapsed and had to be resuscitated. PMID:25139704

Günther, S; Mudra, H; Reichelt, A; Khaladj, N; Hagl, C; Pichlmaier, M

2014-10-01

260

A rare case report of tracheal leech infestation in a 40-year-old woman  

PubMed Central

Leeches are the very rare types of airway foreign body. Here we report a rare case of a 40-year-old woman with tracheal leech infestation. A 40-year-old woman presented 2-month history of dyspnea, occasional haemoptysis. There were foreign body sensation in throat, cough and hoarseness. Computed Tomography (CT) revealed some soft tissue shadow in the upper trachea. Eventually a 5 cm long living leech was smoothly removed from trachea by rigid bronchoscopy under sevoflurane general anesthesia. The airway leech infestation should be kept in mind especially in patients presenting with unexplained haemoptysis, dyspnea, hoarseness and a foreign body sensation in the throat and a history of drinking infested water from streams, pools and spring. General anesthesia might be necessary for the removal of the leech.

Zhang, Peng; Zhang, Rui; Zou, Jian; Zhu, Tao

2014-01-01

261

29 CFR 570.129 - Limited driving of automobiles and trucks by 17-year-olds.  

Code of Federal Regulations, 2013 CFR

...of automobiles and trucks by 17-year-olds. 570.129 Section 570.129 Labor...of automobiles and trucks by 17-year-olds. Section 13(c)(6) of the FLSA provides an exemption for 17-year-olds, but not 16-year-olds,...

2013-07-01

262

29 CFR 570.129 - Limited driving of automobiles and trucks by 17-year-olds.  

Code of Federal Regulations, 2012 CFR

...of automobiles and trucks by 17-year-olds. 570.129 Section 570.129 Labor...of automobiles and trucks by 17-year-olds. Section 13(c)(6) of the FLSA provides an exemption for 17-year-olds, but not 16-year-olds,...

2012-07-01

263

29 CFR 570.129 - Limited driving of automobiles and trucks by 17-year-olds.  

...of automobiles and trucks by 17-year-olds. 570.129 Section 570.129 Labor...of automobiles and trucks by 17-year-olds. Section 13(c)(6) of the FLSA provides an exemption for 17-year-olds, but not 16-year-olds,...

2014-07-01

264

29 CFR 570.129 - Limited driving of automobiles and trucks by 17-year-olds.  

Code of Federal Regulations, 2011 CFR

...of automobiles and trucks by 17-year-olds. 570.129 Section 570.129 Labor...of automobiles and trucks by 17-year-olds. Section 13(c)(6) of the FLSA provides an exemption for 17-year-olds, but not 16-year-olds,...

2011-07-01

265

Automatic quantity processing in 5-year olds and adults.  

PubMed

In this study adults performed numerical and physical size judgments on a symbolic (Arabic numerals) and non-symbolic (groups of dots) size congruity task. The outcomes would reveal whether a size congruity effect (SCE) can be obtained irrespective of notation. Subsequently, 5-year-old children performed a physical size judgment on both tasks. The outcomes will give a better insight in the ability of 5-year-olds to automatically process symbolic and non-symbolic numerosities. Adult performance on the symbolic and non-symbolic size congruity tasks revealed a SCE for numerical and physical size judgments, indicating that the non-symbolic size congruity task is a valid indicator for automatic processing of non-symbolic numerosities. Physical size judgments on both tasks by children revealed a SCE only for non-symbolic notation, indicating that the lack of a symbolic SCE is not related to the mathematical or cognitive abilities required for the task but instead to an immature association between the number symbol and its meaning. PMID:18607652

Gebuis, Titia; Cohen Kadosh, Roi; de Haan, Edward; Henik, Avishai

2009-05-01

266

Chemical properties of two-year-old deciduous species  

SciTech Connect

Contents of ash, hot-water extractives, 1% sodium hydroxide extractives, alcohol-benzene extractive, lignin, holocellulose, alpha-cellulose, and pentosan were determined on two-year-old, short-rotation trees of autumn olive, black alder, black locust, eastern cottonwood, royal paulownia, silver maple, and sycamore. These plantations were established in 1978 on marginal agricultural land that was not suitable for food production in Illinois. Six comparable species of commercial lumber were also analyzed. Test results indicated that all chemical properties did vary with species, above-ground tree portions, and ages of species. The two-year-old juvenile trees had higher average extractives, holocellulose, pentosan, and ash content than did the lumber of matured wood. Black locust possessed the highest values of holocellulose and alpha-cellulose, while the eastern cottonwood had the highest extractive contents. Silver maple had the highest lignin content. Both bark and branches which consisted of about 32% of the mass weight of young trees, had a higher average lignin, extractive and ash content than those of the stemwood. Based on chemical composition, these seven juvenile deciduous species could serve as a raw material for the paper and chemical industries, as well as for energy. 19 references, 8 figures, 6 tables.

Chow, P.; Rolfe, G.L.; Lee, C.S.; White, T.A.

1983-01-01

267

Growth Disorders Among 6-Year-Old Iranian Children  

PubMed Central

Background: Sociodemographic factors are important determinants of weight disorders. National representative studies provide a view on this health problem at national and regional levels. Objectives: This study aimed to assess the distribution of growth disorders in terms of body mass index (BMI) and height in 6-year-old Iranian children using geographical information system (GIS). Materials and Methods: In this cross-sectional nationwide survey, all Iranian children entering public and private elementary schools were examined in a mandatory national screening program in 2009. Descriptive analysis was used to calculate the prevalence of underweight, overweight, obesity, and short stature. Then, ArcGIS software was used to draw the figures. Results: The study population consisted of 955388 children (48.5% girls and 76.5% urban). Overall, 20% of children were underweight, and 14.3% had high BMI, consisted of 10.9% overweight and 3.4% obese. The corresponding figure for short stature was 6.6%; however, these growth disorders were not equally distributed across various provinces. Conclusions: Our results confirmed unequal distribution of BMI and height of 6-year-old children in Iran generally and in most of its provinces particularly. The differences among provinces cannot be fully explained by the socioeconomic pattern. These findings necessitate a comprehensive national policy with provincial evidence-based programs. PMID:25068062

Kelishadi, Roya; Amiri, Masoud; Motlagh, Mohammad Esmaeil; Taslimi, Mahnaz; Ardalan, Gelayol; Rouzbahani, Reza; Poursafa, Parinaz

2014-01-01

268

Two-year-olds' understanding of self-symbols.  

PubMed

This study investigated 48 2.5-year-olds' ability to map from their own body to a two-dimensional self-representation and also examined relations between parents' talk about body representations and their children's understanding of self-symbols. Children participated in two dual-representation tasks in which they were asked to match body parts between a symbol and its referent. In one task, they used a self-symbol and in the other they used a symbol for a doll. Participants were also read a book about body parts by a parent. As a group, children found the self-symbol task more difficult than the doll-task; however, those whose parents explicitly pointed out the relation between their children's bodies and the symbols in the book performed better on the self-symbol task. The findings demonstrate that 2-year-old children have difficulty comprehending a self-symbol, even when it is two-dimensional and approximately the same size as them, and suggest that parents' talk about self-symbols may facilitate their understanding. PMID:24588085

Herold, Katherine; Akhtar, Nameera

2014-09-01

269

Aging in Place in a Retirement Community: 90+ Year Olds  

PubMed Central

Aging in place, an image of growing old in one’s home and maintaining one’s daily routine, is desired by most older adults. To identify variables promoting such independent living in the oldest-old, we examined the association between living situation of a population-based cohort of 90+ year olds with health and lifestyle variables. Of 1485 participants, 53% still lived in their home at a retirement community designed to foster wellness. Those living at home tended to be healthier, with smaller proportions having chronic diseases or hospitalizations in the preceding year and a greater proportion having normal functional ability. Dementia was the chronic disease most significantly related to living situation. In addition to not having dementia, not using a wheelchair or bath aid, receiving meals on wheels, and being married were jointly related to living at home. With the help of family and friends and with a medical and social support system, many 90+ year olds can age in place. This is often because they have a caregiving spouse or paid caregiver.

Paganini-Hill, Annlia

2014-01-01

270

Differences in the clinical spectrum of two adolescent male patients with Alstr?m syndrome  

PubMed Central

Alström syndrome is a rare disorder typified by early childhood obesity, neurosensory deficits, cardiomyopathy, progressive renal and hepatic dysfunction, and endocrinological features such as severe insulin resistance, type 2 diabetes, hyperlipidemia, and hypogonadism. Widespread fibrosis leads to multiple organ failure. Mutations in ALMS1 cause Alström’s syndrome. Two age-matched, unrelated adolescent males of Serbian descent with Alström syndrome underwent an extensive workup of blood chemistries, and ophthalmological, audiological, and genetic evaluations. Although both showed typical features of Alström syndrome in childhood, several differences were observed that have not been reported previously. Patient 1 was first studied at the age of 13 years for multisystemic disease and re-evaluated at the age of 15.5 years. Patient 2 is a 15-year-old boy who presented at birth with epilepsy and psychomotor developmental delay and generalized tonic–clonic seizures with severe cognitive impairment, features not documented previously in this syndrome. Sequencing analysis indicated two novel ALMS1 mutations in exon 8: p.E1055GfsX4 and p.T1386NfsX15. Metabolic and physiological similarities were observed in both patients, including severe insulin resistance, and truncal obesity with fat loss suggestive of partial lipodystrophy, supporting evidence for a role for ALMS1 in adipose tissue function. The unusual phenotypes of clonic–tonic seizures and severe cognitive abnormalities and lipodystrophy-like adiposity pattern have not been documented previously in Alström syndrome and may be an under-reported abnormality. PMID:23188138

Kuburovic, Vladimir; Marshall, Jan D.; Collin, Gayle B.; Nykamp, Keith; Kuburovic, Nina; Milenkovic, Tatjana; Rakic, Sanja; Djuric, Milena; Jecmenica, Jovana; Milenkovic, Svetislav; Naggert, Jurgen K.

2013-01-01

271

Gender identity disorder and autism spectrum disorder in a 23-year-old female.  

PubMed

We describe the case of a 23-year-old woman with Gender Identity Disorder (GID) asking for a cross-sex hormonal treatment with sex reassignment surgery and who was recently diagnosed with Autism Spectrum Disorder (ASD). Gender identity clinics are now reporting an overrepresentation of individuals with ASD among GID patients. The prevalence of ASD is 10-fold higher among GID patients than in general population. However, few case reports or studies have explored the co-occurrence of ASD and GID. This co-occurrence is relevant for diagnostic and clinical management and also raises important theoretical issues. PMID:23835847

Lemaire, Mathieu; Thomazeau, Barbara; Bonnet-Brilhault, Frédérique

2014-02-01

272

Pathology Case Study: A 73-Year-Old Jewish Female with Anemia of Unknown Etiology  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 73-year-old Jewish woman has anemia of unknown etiology and a low reticulocyte count. Visitors are given the microscopic description, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in hematopathology.

Goldblatt, Curtis

2007-12-28

273

Pathology Case Study: An 80-Year-Old Female with a Neck Mass  

NSDL National Science Digital Library

This is an ear nose & throat case study presented by the University of Pittsburgh Department of Pathology in which an 80-year-old female has insular carcinoma of the thyroid (i.e. a neck mass). Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in ear, nose, and throat medicine.

Schubert, Eric

2007-12-20

274

A 25-year-old man with 50 teeth: Astonishing but true!!  

PubMed Central

Retained primary teeth is a well-known process but multiple retained primary, permanent, and supernumerary teeth that too in an asymptomatic, non-syndromic patient is a rare possibility that has rarely been reported in literature. This case report discusses the clinical and radiographic details along with treatment options in a 21-year-old patient having a total number of 50 teeth, i.e., 16 retained primary teeth, 32 permanent teeth, and 2 supernumerary teeth without being associated with any known syndrome complex or metabolic disorder. PMID:24082755

Bhatia, Vishwas; Jain, Nitul; Bhatia, Garima; Garg, Rakesh

2013-01-01

275

Pathology Case Study: Brain Mass in a 62-Year-Old Woman  

NSDL National Science Digital Library

This is a neuropathology case study presented by the University of Pittsburgh Department of Pathology in which a 62-year-old female has a brain mass. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in neuropathology.

Schubert, Eric

2007-12-27

276

Pathology Case Study: Right Cerebellopontine Angle Mass in a 64-Year-Old Woman  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 64-year-old woman is complaining of dizziness and hearing loss. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in neuropathology.

Nine, Jeff S.

2007-08-04

277

Pathology Case Study: Bladder Mass in a 57-Year-Old Woman  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 57-year-old woman has a history of bladder tumors. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in genitourinary pathology.

Hakam, Ardeshir

2007-08-05

278

Pathology Case Study: A 68-Year-Old Woman with Brain Mass in Temporal Lobe  

NSDL National Science Digital Library

This is a neuropathology case study presented by the University of Pittsburgh Department of Pathology in which a 68-year-old female has a temporal tumor with extensive edema. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in neuropathology.

Schubert, Eric

2007-12-24

279

Pathology Case Study: Mesenteric Adenopathy in a 57-Year-Old Woman  

NSDL National Science Digital Library

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 57-year-old woman has had elevated creatinine levels. Visitors are given microscopic and gross descriptions, images, flow cytometry, molecular diagnosis, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in transplant pathology.

Nalesnik, Michael

2007-11-14

280

[Congenital left ventricular aneurysm in a 17-year-old competitive athlete].  

PubMed

We present the case of a 17-year-old competitive athlete with an asymptomatic left ventricular aneurysm (LVA). Echocardiography demonstrated hypoplasia of the septum and a large apical LVA. Magnetic resonance imaging (MRI) detected a very thin and fibrotic wall of the LVA. Due to the potential risk of rupture the LVA was surgically resected and the apex of the left ventricle was covered with a patch plasty. The patient had an event-free postoperative course. Because of the potential risk of arrhythmia, the patient was recommended not to participate further in competitive sport. PMID:21611822

Breker, I M; Butz, T; van Bracht, M; Plehn, G; Vormbrock, J; Prull, M; Yeni, H; Meissner, A; Trappe, H J

2012-03-01

281

A 70-year-old man with intraoperative hypoxia and hypotension during total hip replacement.  

PubMed

A 70-year-old man underwent total hip replacement surgery under general anesthesia, endotracheal intubation, and controlled ventilation, with the patient in left lateral position. Intraoperatively, the patient was hemodynamically stable, with a normal range of pulse, ECG trace, oxygen saturation as measured by pulse oximetry (Spo2), and end-tidal CO2 (etco2). Five minutes after insertion of the hip prosthesis, his heart rate dropped to 30 beats/min, BP to 40/30 mm Hg, Spo2 to 70%, and etco2 to 10 mm Hg. PMID:25367483

Alansari, Mariam A; Abdulmomen, Ahmed A

2014-11-01

282

Pathology Case Sstudy: A 59-Year-Old Female with a Right Atrial Mass  

NSDL National Science Digital Library

This is a cardiovascular pathology case study presented by the University of Pittsburgh Department of Pathology in which a 59-year-old black female has diffuse large cell lymphoma (i.e. right atrial mass). Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in cardiovascular pathology.

Schubert, Eric

2007-12-14

283

Development of 1-year-old computational phantom and calculation of organ doses during CT scans using Monte Carlo simulation  

NASA Astrophysics Data System (ADS)

With the rapidly growing number of CT examinations, the consequential radiation risk has aroused more and more attention. The average dose in each organ during CT scans can only be obtained by using Monte Carlo simulation with computational phantoms. Since children tend to have higher radiation sensitivity than adults, the radiation dose of pediatric CT examinations requires special attention and needs to be assessed accurately. So far, studies on organ doses from CT exposures for pediatric patients are still limited. In this work, a 1-year-old computational phantom was constructed. The body contour was obtained from the CT images of a 1-year-old physical phantom and the internal organs were deformed from an existing Chinese reference adult phantom. To ensure the organ locations in the 1-year-old computational phantom were consistent with those of the physical phantom, the organ locations in 1-year-old computational phantom were manually adjusted one by one, and the organ masses were adjusted to the corresponding Chinese reference values. Moreover, a CT scanner model was developed using the Monte Carlo technique and the 1-year-old computational phantom was applied to estimate organ doses derived from simulated CT exposures. As a result, a database including doses to 36 organs and tissues from 47 single axial scans was built. It has been verified by calculation that doses of axial scans are close to those of helical scans; therefore, this database could be applied to helical scans as well. Organ doses were calculated using the database and compared with those obtained from the measurements made in the physical phantom for helical scans. The differences between simulation and measurement were less than 25% for all organs. The result shows that the 1-year-old phantom developed in this work can be used to calculate organ doses in CT exposures, and the dose database provides a method for the estimation of 1-year-old patient doses in a variety of CT examinations.

Pan, Yuxi; Qiu, Rui; Gao, Linfeng; Ge, Chaoyong; Zheng, Junzheng; Xie, Wenzhang; Li, Junli

2014-09-01

284

Renovating a 65-year-old performing arts center  

SciTech Connect

This article describes the HVAC, electrical and lighting systems that were upgraded in the renovations to the Wang Center for the Performing Arts. The renovations and restorations involved a complete restoration to elaborate interior finishes and a comprehensive upgrade of antiquated core mechanical and electrical systems in a 65-year-old performing arts theater. A new thermal storage cooling system, a new electrical power distribution system, new lighting systems and a new fire protection system were accomplished simultaneously as the theater interior was completely refinished with meticulous detail. The project offered a rare opportunity to integrate current technology with what may at first appear to be obsolete systems to enable the original architectural grandeur to be maintained, yet be fully functional to meet the demanding requirements of a modern performing arts center. It is an example of a successful project that was completed within a very aggressive construction schedule and within a controlled budget.

Gifford, R.S. (R.G. Vanderweil Engineers Inc., Boston, MA (United States))

1994-03-01

285

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

NASA Administrator Dan Goldin (center) presents a bag of special gifts to 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. In the background, between them, are Jonathan's mother, Penny; his grandfather, John Janocka; and his sister, Jaimie.. At left is Mrs. Goldin. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

2000-01-01

286

Similarity predicts liking in 3-year-old children.  

PubMed

Two studies examined the influence of similarity on 3-year-old children's initial liking of their peers. Children were presented with pairs of childlike puppets who were either similar or dissimilar to them on a specified dimension and then were asked to choose one of the puppets to play with as a measure of liking. Children selected the puppet whose food preferences or physical appearance matched their own. Unpacking the physical appearance finding revealed that the stable similarity of hair color may influence liking more strongly than the transient similarity of shirt color. A second study showed that children also prefer to play with a peer who shares their toy preferences, yet importantly, show no bias toward a peer who is similar on an arbitrary dimension. The findings provide insight into the earliest development of peer relations in young children. PMID:20092828

Fawcett, Christine A; Markson, Lori

2010-04-01

287

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

NASA Administrator Dan Goldin (center) greets 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. In the background, between them, are Jonathan's mother, Penny; his grandfather, John Janocka; and his sister, Jaimie.. At left is Mrs. Goldin. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

2000-01-01

288

NASA Administrator Dan Goldin greets 10-year-old VIP.  

NASA Technical Reports Server (NTRS)

NASA Administrator Dan Goldin (center) talks to 10-year-old Jonathan Pierce (right), who is garbed in a protective cooling suit designed by NASA. In the background, between them, are Jonathan's mother, Penny; his grandfather, John Janocka; and his sister, Jaimie. At left is Mrs. Goldin. Jonathan suffers from erythropoietic protoporphyria, a rare condition that makes his body unable to withstand ultraviolet rays. The suit allows him to be outside during the day, which would otherwise be impossible. Jonathan's trip was funded by the Make-A-Wish Foundation and included a visit to Disney World. He and his family were among a dozen VIPs at KSC to view the launch of STS-99.

2000-01-01

289

Orbital histiocytic sarcoma in a 2-year-old child.  

PubMed

Histiocytic sarcoma (HS) is an exceedingly rare hematologic malignancy that typically presents in the skin, gastrointestinal tract, and lymph nodes. Few cases of HS have been reported in the head and neck. This study describes the case of a 2-year-old girl presenting with 2 weeks of left lower eyelid swelling. Diagnostic testing and biopsy revealed a large inferior orbital mass causing severe bony destruction with extension into the sinuses. Pathologic analysis revealed classic features of HS. To the best of knowledge, no previous case of HS occurring in the orbit of a child has been reported. This study presents an exceedingly rare case of HS in a young child presenting with eyelid swelling. In addition, this case report is in compliance with HIPAA regulations. PMID:24807797

Aakalu, Vinay K; Patel, Rakesh M; Lim, Janet; Setabutr, Pete

2014-01-01

290

Late Established Mutans Streptococci in Children over 3 Years Old  

PubMed Central

Acquisition of mutans streptococci has been reported to most commonly occur at approximately 26 months of age. In the present study, we detected Streptococcus mutans and S. sobrinus using polymerase chain reaction (PCR) assays in children, then re-examined the subjects to determine the time of acquisition of these bacteria over a 1-year period. The subjects were 57 children ranging in age from 3 to 5 years old, each with primary dentition. Plaque samples were collected from all erupted tooth sites using a sterile toothbrush. PCR assays were performed to detect the targeted mutans streptococci at the beginning of the study (baseline) and after 1 year. At the baseline examination, the prevalence of S. mutans and S. sobrinus was 61.4% and 54.4%, respectively, in all subjects, of whom 14 (24.6%) were positive for S. mutans alone, 10 (17.5%) for S. sobrinus alone, and 21 (36.8%) for both S. mutans and S. sobrinus, with 12 (21.1%) negative for both. After 1 year, 4 of 22 (18.2%) subjects newly had acquired S. mutans and 15 of 26 (57.7%) had aquired S. sobrinus, while 5 (8.8%) remained negative for both bacteria. The age of the first positive S. mutans finding ranged from 49 to 71 months, while that for S. sobrinus ranged from 49 to 81 months old. Our results suggest that S. sobrinus becomes established later than S. mutans in the oral cavities of children over the age of 3 years old. PMID:20339489

Okada, Mitsugi; Taniguchi, Yoshiko; Hayashi, Fumiko; Doi, Takako; Suzuki, Junji; Sugai, Motoyuki; Kozai, Katsuyuki

2010-01-01

291

De novo mutation in a male patient with Fabry disease: a case report  

PubMed Central

Background Fabry disease is an X-linked inherited metabolic condition where the deficit of the ?-galactosidase A enzyme, encoded by the GLA gene, leads to glycosphingolipid storage, mainly globotriaosylceramide. To date, more than 600 mutations have been identified in human GLA gene that are responsible for FD, including missense and nonsense mutations, small and large deletions. Such mutations are usually inherited, and cases of de novo onset occur rarely. Case presentation In this article we report an interesting case of a 44-year-old male patient suffering from a severe form of Fabry disease, with negative family history. The patient showed signs such as cornea verticillata, angiokeratomas, cardiac and neurological manifestations, an end-stage renal disease and he had low ?-galactosidase A activity. We detected, in this subject, the mutation c.493 G?>?C in the third exon of the GLA gene which causes the amino acid substitution D165H in the protein. This mutation affects the amino acid - belonging to the group of buried residues - involved, probably, in the preservation of the protein folding. Moreover, studies of multiple sequence alignment indicate that this amino acid is highly conserved, thus strengthening the hypothesis that it is a key amino acid to the enzyme functionality. The study of the relatives of the patient showed that, surprisingly, none of the members of his family of origin had this genetic alteration, suggesting a de novo mutation. Only his 11-year-old daughter - showing acroparaesthesias and heat intolerance with reduced enzymatic activity - had the same mutation. Conclusions We suggest that a non-inherited mutation of the ?-galactosidase A gene is responsible for Fabry disease in the patient who had reduced enzyme activity and classical clinical manifestations of the disease. In a family, it is rare to find only one Fabry disease affected subject with a de novo mutation. These findings emphasize the importance of early diagnosis, genetic counselling, studying the genealogical tree of the patients and starting enzyme replacement therapy to prevent irreversible vital organ damage that occurs during the course of the disease. PMID:24398019

2014-01-01

292

[Therapy for male patients with sexual dysfunction].  

PubMed

Phosphodiasterase type 5 inhibitors (sildenafil, vardenafil, tadalafil) are the first line symptomatic therapy for patients with erectile dysfunction. The patient should receive a meticolous information on the use of these drugs and their possible side effects. These drugs are safe and can be used even in patients with stable cardiovascular disease. Patients not responding to oral drugs may be offered intraurethral or intracavernous alprostadil. Vacuum constriction devices are a second line option more acceptable to older patients. Penile prosthesis are very seldom used in Switzerland and vascular surgery is a vanishing option. Testosterone substitution is seldom needed in this setting. Treatment of premature ejaculation subdivides into behavioural therapy ("stop-start" or "squeeze" technique) and drug therapy as well. Topical therapy with lidocaine/prilocaine-containing medications to be applied before sexual intercourse and a oral daily off label use therapy with selective serotonin re-uptake inhibitors (paroxetine, fluoxetine, sertraline) can be offered. Dapoxetine, a potent selective serotonin reuptake inhibitor with short half life time, is the first officially approved medication for the treatment of premature ejaculation and should be available soon in Switzerland. PMID:20235039

Casella, Roberto

2010-03-01

293

Male genitoplasty for 46 XX congenital adrenal hyperplasia patients presenting late and reared as males  

PubMed Central

Aim: To evaluate the clinical profile and management of 46 XX Congenital Adrenal Hyperplasia (CAH) patients presenting with severe virilization and assigned a male gender. Materials and Methods: Of 173 children diagnosed with CAH at the Pediatric Intersex Clinic since 1980, seven children with CAH presented late with severe virilization and were reared as males. All of them were assigned the male sex with removal of the female adnexa. Six were treated with male genitoplasty. Appropriate hormonal supplementation was offered after puberty. Results: The mean age at presentation was 14.2 years (7 – 21). Six patients had presented after puberty, only one at seven years of age. Staged male genitoplasty comprising of chordee correction, male urethroplasty, and bilateral testicular prosthesis was performed. The female adnexa (uterus, ovaries, most of the upper vagina, and the fallopian tubes) were removed. The mental makeup was masculine in six and bigender in one. Bilateral mastectomy was performed at puberty in all. Hormonal treatment comprised of glucocorticoids and testosterone. Six patients were comfortable with the outcome of the masculinizing genitoplasty. One had a short-sized phallus. One had repeated attacks of urinary tract infection arising from the retained lower vaginal pouch. Social adjustments were good in all, except in one who had a bigender mental makeup. Conclusion: CAH patients with severe virilization presenting late and reared as males are extremely rare. However, the assigned gender can be retained adequately as males, meeting the socioeconomic compulsions of the society. The results are satisfactory following appropriate surgical procedures and hormonal supplementation. PMID:23226638

Sharma, Shilpa; Gupta, Devendra K.

2012-01-01

294

The middle ear pressure does not change after adenotonsillectomy in children younger than 10 years old.  

PubMed

OBJECTIVE. In children aged less than 10 years, to assess whether adenotonsillectomy has some permanent or transitory effect on middle ear pressure. MATERIAL AND METHODS. 20 children aged 4 to 9 years old (13 girls and 7 boys) participated in the study. The day before surgery and on days 1, 7, 14 and 21 after adenotonsillectomy both tympanometry and pure tone audiometry were performed. During surgery, medication consisted in dexamethasone, atropine, propofol and sevoflurane. RESULTS. Before surgery, the middle ear pressure was within the range of 0 ± 99 daPa. On day 1 of the followup study, the average right and left middle ear pressure decreased less than -99 daPa in 6 patients aged 4 to 9 years old (2 girls and 4 boys), with a body mass index from 11.9 to 16.6. At day 7 of follow-up, the middle ear pressure increased and none of the patients showed a pressure less than -99 daPa. Before surgery and during the 21 days of follow-up, hearing thresholds were always ? 20 dB nHL. No significant difference was observed between children with or without an average middle ear pressure lower than -99 daPa on their age, weight, height, body mass index or duration of the surgery. CONCLUSIONS. After adenotonsillectomy, children aged 4 to 9 years old who received dexamethasone, atropine and sevoflurane might develop negative middle ear pressure with no hearing loss, which may resolve in 1 week. After adenotonsillectomy, in patients with otalgia or risk factors for middle ear disease, closer evaluation of middle ear pressure may be advisable. PMID:24960325

Montaño-Velázquez, Bertha Beatriz; Villanueva-Padrón, Laura Alejandra; Conde-Vázquez, Ernesto; Alvarez-Romero, Edith; Romero-Asato, Jaime Gaspar; Jáuregui-Renaud, Kathrine

2014-01-01

295

Malignant Fibrous Histiocytoma of the Breast in Young Male Patient: A Case Report and a Review of the Literature  

PubMed Central

Malignant Fibrous Histiocytoma (MFH) is a fairly common tumor in the deep soft tissues: the most frequent primary sites are the lower (49%) and upper (19%) limbs, but it has been reported even in the retroperitoneum and abdomen (16%), while localization in the breast is extremely rare (1-2). Breast cancer is rarely seen in males, accounts for approximately 1% of all breast cancer, and the breast sarcomas constitute less than 1% of breast tumors in both sexes. In the review of the literature, this is the third male and first young male with MFH. Here, we present a 37-years-old male patient who is diagnosed to have malignant fibrous histiocytoma in a variant of pleomorphic fusiform cell localized in the left breast. Following the wide local excision, the patient was given an adjuvant 50?Gy of external radiotherapy. He remained alive and well after 42 months of followup. We believe that reporting such few cases would contribute to forming treatment algorithms of rare tumors. PMID:23573437

Kocak Uzel, Esengul; Figen, Metin; Bek, Tuba Tulin; Inanc, Kubilay; Onder, Senem; Kizilkaya, Hazim orhan

2013-01-01

296

A 61-year-old woman with osteomalacia and a thoracic spine lesion.  

PubMed

Phosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia. It is generally found in the soft tissue and bone of the extremities. We report a case of a 61-year-old female with long-standing osteomalacia who was found to have PMT-MCT of the thoracic spine. There have been very few previously reported cases of PMT involving the spinal vertebrae and neuropathologists should be aware of this lesion. Recognition of PMT-MCT is critical for optimal patient care since complete surgical resection without additional therapy is curative. PMID:20438469

Marshall, Ann E; Martin, Sarah E; Agaram, Narasimhan P; Chen, Jey-Hsin; Horn, Eric M; Douglas-Akinwande, Annette C; Hattab, Eyas M

2010-03-01

297

[A case of childhood granulomatous perioral dermatitis (CGPD) in a three year old boy from Madagascar].  

PubMed

A case of childhood granulomatous perioral dermatitis (CGPD)/facial Afro-Caribbean childhood eruption (FACE) in a three year old boy from Madagascar is described. This disorder occurs predominantly in black children until puberty. It is a relatively uncommon condition of unknown aetiology characterized by a monomorphic, papular eruption around the mouth, nose and eyes. The disorder looks like sarcoidosis, but it is benign and self-limited and not associated with any systemic manifestations. In our case we treated the patient with Elidel (pimecrolimus) with an excellent result. PMID:18252166

Mørtz, Charlotte Gotthard; Deleuran, Mette Søndergaard

2008-01-28

298

Anaphylaxis to lidocaine with tolerance to articaine in a 12 year old girl.  

PubMed

True allergic reactions to local anesthetics are extremely rare and constitute less than 1% of all reactions. In addition, many of those allergic reactions are caused by the preservative constituents of the local anesthetics. Here we report a 12 year old girl with anaphylaxis to lidocaine (an amide local anesthetic) on two occasions. The allergy was confirmed by positive skin prick test to the drug. Skin testing and challenge to another amide local anesthetic (articaine) were negative. Subsequently, its use was well tolerated in a dental procedure. Up to our knowledge, this is the first report of a patient who is allergic to lidocaine and tolerant to articaine. PMID:25067903

Al-Dosary, Khalid; Al-Qahtani, Ahmad; Alangari, Abdullah

2014-07-01

299

Pathology Case Study: Brainstem Mass in a 2-Year-Old Female  

NSDL National Science Digital Library

The Department of Pathology at the University of Pittsburgh School of Medicine maintains a website with hundreds of case studies and sample diagnoses. These case studies are great learning tools for those studying medicine and planning on entering a medical field. This specific case involves the diagnosis of a 2-year-old female patient suffering from neck pain. A gross description of an MRI scan, and microscopic images are provided. Using the information provided, students are encouraged to make their own diagnosis and then check it against the official findings in the "Final Diagnosis" section.

Nine, Jeff S.

2007-08-09

300

Metallic foreign body in the appendix of 3-year-old boy.  

PubMed

Foreign body-induced appendicitis is a rare but well-known entity. This condition was discovered during the first appendectomy performed almost 275 years ago. For the pediatric surgeon, evaluation of a patient for swallowed foreign bodies is common, and most foreign bodies traverse the gastrointestinal tract without incident. However, when the foreign body becomes incarcerated in the appendix, a prophylactic appendectomy is recommended to prevent appendicitis. We present the case of an asymptomatic 3-year-old boy with a metallic foreign body lodged in the appendix that was treated with a fluoroscopically assisted laparoscopic appendectomy and discuss treatment of sharp vs blunt foreign bodies of the appendix. PMID:18970950

Hartin, Charles W; Lau, Stanley T; Caty, Michael G

2008-11-01

301

Ectopic Thoracic Kidney and End-Stage Renal Disease in a 38-Year-Old Nigerian  

PubMed Central

This patient is a 38-year-old housewife who presented with a one-month history of difficulty, in breathing, chest pain and bilateral leg swelling and had a blood pressure of 260/150?mmHg, features of malignant hypertension and hypertensive heart disease. Chest CT scan revealed a chest location of the left kidney. She also had elevated serum urea and creatinine and proteinuria (++). The right kidney was normally located with loss of corticomedullary differentiation. She is on maintenance haemodialysis and is being worked up for possible left nephrectomy. PMID:24527243

Ekrikpo, U. E.; Effa, E. E.; Akpan, E. E.

2013-01-01

302

Diffuse Alveolar Hemorrhage in a 39-year-old Woman: Unusual Initial Presentation of Microscopic Polyangiitis  

PubMed Central

Microscopic polyangiitis (MPA) is a necrotizing vasculitis involving the small vessels without granulomatous inflammation. Most MPA initially presents with renal involvement without pulmonary involvement. Isolated and initially presenting alveolar hemorrhage is very rare. The patient was a 39-year-old female with a progressive cough, dyspnea, and blood-tinged sputum for the previous 5 days. We determined that her condition was MPA though VATS lung biopsy and renal biopsy. After 2 months of steroid therapy, the chest lesions had improved. We report here a rare case of MPA with isolated and initial involvement of the lung with a review of the literature. PMID:22324034

Kim, Jae Jun; Wang, Young-Pil; Park, Hyung Joo; Sung, Sook-Whan; Kim, Do-Yeon

2011-01-01

303

Invasive ductal carcinoma of the breast in a 14-year-old girl.  

PubMed

Breast cancer is rare in children and adolescents. In particular, there are very few cases of invasive ductal carcinoma in childhood. We report a case of invasive ductal carcinoma of the breast in a 14-year-old girl presenting as a palpable mass. While the tumor demonstrated a relatively benign appearance on ultrasound, magnetic resonance imaging revealed typical malignant features. Several polymorphisms of single nucleotide variation were observed on gene analysis. The patient underwent breast conserving surgery and received subsequent concurrent chemo-radiation therapy. An awareness that ductal carcinoma of the breast rarely occurs in children is important to detect early stage breast cancer. PMID:24997789

Kim, Joo Yeon; Kim, Yun Ju; Kim, Sung Hun; Kang, Bong Joo; Song, Byung Joo

2014-11-01

304

Progressive dystonia in a 12-year-old boy.  

PubMed

Pantothenate kinase-associated neurodegeneration (PKAN) (MIM 234200; Hallervorden-Spatz syndrome) is a degenerative, autosomal recessive disorder in childhood, currently without specific treatment. In contrast to variable clinical features, T2-weighted magnetic resonance images show a characteristic 'eye-of-the-tiger sign' in the globus pallidus due to excess iron deposition. Recently a defect in pantothenate kinase, the key regulatory enzyme in the synthesis of coenzyme A from pantothenate, has been identified as the cause of the disease. We report a 12-year-old boy with progressive rigidity, dystonia, impaired voluntary movement, dysarthria, and mental deterioration. Over 10 years the boy had been misdiagnosed with clumsiness, emotional and behavioural deficits, and attention deficit disorder, before neuroimaging was performed showing the characteristic 'eye-of-the-tiger sign'. Molecular analyses confirmed two mutations in the PANK2 gene [coding sequence of a gene that has homology to murine pantothenate kinase-1]. We conclude that in progressive childhood dystonia, PKAN should be considered and magnetic resonance imaging performed early. The newly described defect of the pantothenate kinase enzyme enables a novel therapeutic approach to be considered, based on the mutation analyses of the PANK2 gene, as well as the prenatal diagnosis of this disorder. PMID:12697433

Klepper, Jörg; Schaper, Jörg; Raca, Gordana; Coryell, Jason; Das, Soma; Hayflick, Susan J; Voit, Thomas

2003-01-01

305

In urban South Africa, 16 year old adolescents experience greater health equality than children.  

PubMed

Despite the strongly established link between socio-economic status (SES) and health across most stages of the life-course, the evidence for a socio-economic gradient in adolescent health outcomes is less consistent. This paper examines associations between household, school, and neighbourhood SES measures with body composition outcomes in 16 year old South African Black urban adolescents from the 1990 born Birth to Twenty (Bt20) cohort. Multivariable regression analyses were applied to data from a sub-sample of the Bt20 cohort (n=346, 53% male) with measures taken at birth and 16 years of age to establish socio-economic, biological, and demographic predictors of fat mass, lean mass, and body mass index (BMI). Results were compared with earlier published evidence of health inequality at ages 9-10 years in Bt20. Consistent predictors of higher fat mass and BMI in fully adjusted models were being female, born post term, having a mother with post secondary school education, and having an obese mother. Most measures of SES were only weakly associated with body composition, with an inconsistent direction of association. This is in contrast to earlier findings with Bt20 9-10 year olds where SES inequalities in body composition were observed. Findings suggest targeting obesity interventions at females in households where a mother has a high BMI. PMID:23876525

Griffiths, Paula L; Johnson, William; Cameron, Noël; Pettifor, John M; Norris, Shane A

2013-12-01

306

Pantoea agglomerans bacteremia in a 65-year-old man with acute myeloid leukemia: case report and review.  

PubMed

A 65-year-old man with a recent history of acute leukemia was admitted with complaints of chills and rigors. He had a long-standing Hickman catheter which was removed following the isolation of a gram negative rod later identified as Pantoea agglomerans. The patient recovered with antimicrobial therapy. Pantoea species are rare causes of clinically relevant infections. PMID:18176303

Uche, Anayochukwu

2008-01-01

307

Curative resection of hilar cholangiocarcinoma in a 25-year-old woman: report of a case.  

PubMed

A 25-year-old woman was referred to our hospital with persistent upper abdominal pain. Preoperative imaging studies revealed a hilar bile duct stricture with portal venous encasement, and the patient underwent curative resection involving extended left hepatectomy and segmental portal vein resection. The pathological findings demonstrated a well-differentiated tubular adenocarcinoma of the bile duct with regional lymph node metastasis (stage IIIB according to the UICC TNM classification), as well as the overexpression of p53 proteins and the K-ras gene mutation in tumor cells. The patient has shown no evidence of recurrence in the 10 months since the operation. Although there are several reports of relatively young adults with cholangiocarcinoma, the majority of such patients demonstrate either an anomalous arrangement of the pancreaticobiliary duct system or primary sclerosing cholangitis. The absence of any morphological abnormalities in this patient's biliary system implicates de novo carcinogenesis as the most likely cause of the cholangiocarcinoma. PMID:23580078

Murakami, Sae; Ajiki, Tetsuo; Ueno, Kimihiko; Sawa, Hidehiro; Tsuchida, Shinobu; Otsubo, Izuru; Yoshida, Yuko; Shinozaki, Kenta; Okazaki, Taro; Matsumoto, Ippei; Fukumoto, Takumi; Ku, Yonson

2014-07-01

308

A 71-year-old man with anaphylaxis after eating grits  

PubMed Central

The allergist is frequently called on to evaluate patients after episodes of anaphylaxis to determine the cause and implement preventive measures that will reduce the patient’s risk from future episodes. The etiology of anaphylaxis can be the result of numerous causes that may go undiagnosed if a thorough evaluation is not performed. We present a 71-year-old man with no history of food allergy or atopy who presented to the emergency room and then our allergy clinic for evaluation after suffering anaphylaxis after a meal of grits and shrimp. The underlying diagnosis, which was subsequently determined, requires a high index of suspicion and should be included in the differential diagnosis of any patient presenting with unexplained anaphylaxis. PMID:22370536

Posthumus, Jonathon; Borish, Larry

2014-01-01

309

Intelligence and Visual Motor Integration in 5-Year-Old Children with 22q11-Deletion Syndrome  

ERIC Educational Resources Information Center

The purpose of this study was to explore the relationship between intelligence and visual motor integration skills in 5-year-old children with 22q11-deletion syndrome (22q11DS) (N = 65, 43 females, 22 males; mean age 5.6 years (SD 0.2), range 5.23-5.99 years). Sufficient VMI skills seem a prerequisite for IQ testing. Since problems related to…

Duijff, Sasja; Klaassen, Petra; Beemer, Frits; Swanenburg de Veye, Henriette; Vorstman, Jacob; Sinnema, Gerben

2012-01-01

310

Children's Readiness Gains in Publically Funded, Community-Based Pre-Kindergarten Programs for 4 Year Olds and Preschool for 3 Year Olds  

ERIC Educational Resources Information Center

Background: Many states provide public funding to facilitate school readiness for community-based pre-K and preschool programs for 4 year old children and "at risk" 3 year old children. Little research exists on the school readiness gains of children participating in these "garden variety" community-based programs. Objective:…

Goldstein, Peggy; Warde, Beverly; Peluso, Paul

2013-01-01

311

Dynamics of hand preference in 4 year-old children.  

PubMed

Hand preference in groups of 4 year-old children towards either end of the skill continuum (as determined by the Movement ABC test) was explored by means of a catching task in which the 'direction of approach of the ball' was used as a control parameter within a dynamical systems framework. In Condition 1, the ball direction was systematically scaled in degrees from the right side of the subject to the left and vice versa. In Condition 2, the spatial location of the ball direction was varied randomly, rather than systematically, over the same range as for Condition 1. In both conditions, the two groups of children were shown to switch between hands (from left to right and vice versa) at well-defined positions on the scale. The different scale values obtained when ball direction was scaled from left to right compared with right to left were used to define hysteresis areas. These areas were more extensive and located more to the left of the midline for the group towards the less skilled end of the continuum than for those towards the more skilled end. Additionally, the less-skilled children were shown to use the right hand more to catch the balls delivered to the left side than did the more skilled children. In Condition 3, objects were placed on the table of the ball-delivery apparatus in order to make the catching action more complicated. The less skilled group were shown to use the right hand more than the left hand in all catching positions whereas the more skilled group showed an equal usage of both catching regimes. PMID:11853858

Rostoft, M S; Sigmundsson, H; Whiting, H T A; Ingvaldsen, R P

2002-04-15

312

Health Concerns (excluding AIDS) for Male Homosexual Patients  

PubMed Central

Since 1981, the Acquired Immune Deficiency Syndrome (AIDS) has emerged as the major infectious epidemic of our time and has focused much attention on the male homosexual community. While AIDS is the most serious of gay-related health concerns, it is only one of several infectious diseases that have particular relevance for this group of patients. In addition, the mere acknowledgement of homosexuality by a male patient evokes unique psychosocial concerns that are important considerations for the primary health-care provider. The author of this article describes an approach to gay male patients for those who provide health care to such men and provides a review of specific infectious diseases (excluding AIDS) for which they are at risk. PMID:21253077

Willoughby, Brian C.

1988-01-01

313

A Case of Human Pulmonary Dirofilariasis in a 48-Year-Old Korean Man  

PubMed Central

Dirofilariasis is a rare disease in humans. We report here a case of a 48-year-old male who was diagnosed with pulmonary dirofilariasis in Korea. On chest radiographs, a coin lesion of 1 cm in diameter was shown. Although it looked like a benign inflammatory nodule, malignancy could not be excluded. So, the nodule was resected by video-assisted thoracic surgery. Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen. In the center of the necrotic nodules, a degenerating parasitic organism was found. The parasite had prominent internal cuticular ridges and thick cuticle, a well-developed muscle layer, an intestinal tube, and uterine tubules. The parasite was diagnosed as an immature female worm of Dirofilaria immitis. This is the second reported case of human pulmonary dirofilariasis in Korea. PMID:24327784

Kang, Hyo Jae; Park, Young Sik; Lee, Chang-Hoon; Lee, Sang-Min; Yim, Jae-Joon; Yoo, Chul-Gyu; Kim, Young Whan; Han, Sung Koo; Chai, Jong-Yil

2013-01-01

314

A case of human pulmonary dirofilariasis in a 48-year-old Korean man.  

PubMed

Dirofilariasis is a rare disease in humans. We report here a case of a 48-year-old male who was diagnosed with pulmonary dirofilariasis in Korea. On chest radiographs, a coin lesion of 1 cm in diameter was shown. Although it looked like a benign inflammatory nodule, malignancy could not be excluded. So, the nodule was resected by video-assisted thoracic surgery. Pathologically, chronic granulomatous inflammation composed of coagulation necrosis with rim of fibrous tissues and granulations was seen. In the center of the necrotic nodules, a degenerating parasitic organism was found. The parasite had prominent internal cuticular ridges and thick cuticle, a well-developed muscle layer, an intestinal tube, and uterine tubules. The parasite was diagnosed as an immature female worm of Dirofilaria immitis. This is the second reported case of human pulmonary dirofilariasis in Korea. PMID:24327784

Kang, Hyo Jae; Park, Young Sik; Lee, Chang-Hoon; Lee, Sang-Min; Yim, Jae-Joon; Yoo, Chul-Gyu; Kim, Young Whan; Han, Sung Koo; Chai, Jong-Yil; Lee, Jinwoo

2013-10-01

315

Cushing syndrome secondary to CRH-producing Wilms tumor in a 6 year old.  

PubMed

Abstract Cushing syndrome is caused by prolonged exposure to elevated serum cortisol. It is uncommon in children, and etiology includes pituitary adenoma, adrenal tumor, and exogenous glucocorticoid administration. Rarely, it is paraneoplastic in origin. We present a case of paraneoplastic Cushing syndrome due to Wilms tumor that secreted corticotropin-releasing hormone (CRH). A 6-year-old male presented with polyphagia and weight gain. He showed Cushingoid appearance, hypertension, and palpable left flank mass. Serum cortisol and adrenocorticotropic hormone (ACTH) levels were elevated. Computed tomography showed a neoplasm originating from the left kidney. Pathologic diagnosis of Wilms tumor was made upon nephroureterectomy. Immunohistochemical staining was positive for CRH and negative for ACTH. All features of Cushing syndrome disappeared after surgery. This represents a rare case of Cushing syndrome secondary to Wilms tumor in which CRH production has been demonstrated. PMID:25153573

Lee, Moon Hee; Cho, Uiju; Lee, Jae-Wook; Cho, Won-Kyoung; Jung, Min Ho; Chung, Nak Gyun; Cho, Bin; Choi, Yeong Jin; Lee, Myung Duk; Suh, Byung-Kyu

2014-11-01

316

Neurosyphillis presenting with normal pressure hydrocephalus in a 76 year old man  

PubMed Central

Summary Background: Normal pressure hydrocephalus (NPH) is composed of gait abnormalities, urinary incontinence and decline in mentation. It is uncommonly induced by syphilitic infection. Case Report: A 76 year-old male present with gait disturbances, urinary incontinence, declining vision and cognition, with a known diagnosis of NPH. He underwent therapeutic lumbar puncture (LP), which demonstrated leukocytosis and elevated protein. Venereal disease research laboratory testing (VDRL) was reactive in a 1:64 dilution with positive fluorescent Treponemal Antibody (FTA-Abs). The subject was treated with 14 days of Intravenous (IV) Penicillin 3 million units for 3 weeks and intramuscular benzathine PCN for 2 shots, with marked clinical improvement. Conclusions: The incidence of Tabes Dorsalis is limited in the age of penicillin, especially in subjects without HIV. Subjects are diagnosed with either LP RPR or VDRL, confirmed with FTA-Abs. Common treatment is IV PCN 1.4–3 mU for 10–14 days. PMID:23569521

Mok, Shaffer R.S.; Punjabi, Vivek; Shklar, David L.

2012-01-01

317

Genetic and Environmental Contributions to Sleep-Wake Behavior in 12-Year-Old Twins  

PubMed Central

Study Objectives: To examine the role of genetic and environmental factors on sleep behavior in 12-year-old twins matched for family environment. Design: Population-based twin cohort. Setting: Participants were assessed in their home environment. Patients or Participants: One hundred thirty-two adolescent twins comprising 25 monozygotic (MZ) and 41 dizygotic (DZ) twin pairs; aged 12.2 ± 0.1 y (mean ± standard deviation). Interventions: N/A. Measurements and Results: For 2 weeks in their home environment, participants wore a wrist activity monitor and completed a daily sleep diary. Sleep diaries included reports of bedtime, wake time, and estimated sleep onset time. Mean timing, duration, and quality of sleep during the 2 weeks were calculated for each individual and compared within twin pairs. MZ twin correlations were higher than the DZ correlations for total sleep time (MZr = 0.64; DZr = 0.38) and sleep onset latency (MZr = 0.83; DZr = 0.53) and significantly higher for wake after sleep onset (MZr = 0.66; DZr = 0.04) and sleep efficiency (MZr = 0.82; DZr = 0.10). Univariate modeling showed additive genetic factors accounted for 65% of the variance in total sleep time, 83% in sleep onset latency, and 52% and 57% of the variance in wake after sleep onset and sleep efficiency, respectively. A predominant influence of shared environment was found on the timing of sleep (67% for sleep start time, 86% for sleep end time). Conclusions: There is a strong genetic influence on the sleep-wake patterns of 12-year-old adolescents. Genes have a greater influence on sleep initiation and sleep maintenance and a smaller role in sleep timing, likely to be influenced by family environment. Citation: Sletten TL; Rajaratnam SMW; Wright MJ; Zhu G; Naismith S; Martin NG; Hickie I. Genetic and environmental contributions to sleep-wake behavior in 12-year-old twins. SLEEP 2013;36(11):1715-1722. PMID:24179306

Sletten, Tracey L.; Rajaratnam, Shantha M.W.; Wright, Margaret J.; Zhu, Gu; Naismith, Sharon; Martin, Nicholas G.; Hickie, Ian

2013-01-01

318

Video games use patterns and parenteral supervision in a clinical sample of Hispanic adolescents 13-17 years old.  

PubMed

Video games have become a popular entertainment among adolescents. Although some video games are educational, there are others with high content of violence and the potential for other harmful effects. Lack of appropriate supervision of video games use during adolescence, a crucial stage of development, may lead to serious behavioral consequences in some adolescents. There is also concern about time spent playing video games and the subsequent neglect of more developmentally appropriate activities, such as completing academic tasks. Self-administered questionnaires were used to assess video game use patterns and parental supervision among 55 adolescent patients 13-17 years old (mean age 14.4 years; 56.4% males) and their parents. Parental supervision /monitoring of the adolescents video games use was not consistent and gender related differences were found regarding their video game use. Close to one third (32%) of the participants reported video game playing had interfered with their academic performance. Parents who understood video games rating system were more likely to prohibit their use due to rating. These findings underscore the need for clear and consistently enforced rules and monitoring of video games use by adolescents. Parents need to be educated about the relevance of their supervision, video games content and rating system; so they will decrease time playing and exposure to potentially harmful video games. It also supports the relevance of addressing supervision, gender-based parental supervisory styles, and patterns of video games use in the evaluation and treatment of adolescents. PMID:22788074

Colón-de Martí, Luz N; Rodríguez-Figueroa, Linnette; Nazario, Lelis L; Gutiérrez, Roberto; González, Alexis

2012-01-01

319

Angioedema in a 47-year-old woman with hypocomplementemic urticarial vasculitis syndrome.  

PubMed

Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a type III hypersensitivity reaction characterized by urticaria with persistent acquired hypocomplementemia. Although HUVS is uncommon, it is important for physicians to be familiar with this disease, as the initial presentation is often life-threatening angioedema. The author reports the case of a 47-year-old white woman with a history of HUVS. She presented to an outpatient clinic complaining of a rash and difficulty swallowing. Urticaria and angioedema were diagnosed. The patient was given epinephrine in the clinic and then transferred to the hospital. Laboratory testing confirmed urticaria, and the patient was given intravenous methylprednisolone sodium succinate and an additional dose of epinephrine. After 1 week, the patient's angioedema improved. PMID:22331803

Jones, Julie M; Reich, Keith A; Raval, Deena G

2012-02-01

320

Varicella Pneumonia in a 39-year-old Female in Third Trimester Twin Pregnancy  

PubMed Central

SUMMARY CONFLICT OF INTEREST: none declared. Introduction Chickenpox is disease caused by varicella-zoster virus (VZV), with possibly devastated consequences during pregnancy, for mother and neonate. Pneumonia is most common complication in pregnancy with very high mortality. Case report A 39-year-old female in third trimester twin pregnancy, referred to Clinic for infectious diseases in Sarajevo, with five days history of illness. Before the admission her condition get worse, with fatigue, exhaustion, and shortness of breath. In a first three days patient was febrile, tachydispnoic and ortopnoic. We started therapy with acyclovir and antibiotic. After four days we had detoriation in patient’s condition. Chest X-ray revealed infiltrative shadows in basal parts of lung. Antimicrobial therapy was changed and corticosteroids were associated. Significant improvement was noticed after five days of therapy. Conclusion Varicella pneumonia during third trimester may have serious consequences for mother and child, with possible fatal outcome. PMID:24493990

Baljic, Rusmir; Hadzovic, Meliha; Mehanic, Snjezana; Lukovac, Enra; Koluder-Cimic, Nada; Baljic, Izet; Imsirovic, Bilal

2012-01-01

321

Symbolic Modes of Activity in Two-Year-Old Children.  

ERIC Educational Resources Information Center

The influence of age, sex, representational detail of objects (prototypicality) and adult play suggestions on children's progression of pretend behaviors was studied. A checklist was developed and utilized for coding the responses of 20 children (10 males, 10 females), to objects judged to be high and low prototypical by 12 adults. Children ranged…

Hrncir, Elizabeth J.

322

First Diagnosis of Inflammatory Bowel Disease in a 91-Year-Old Man  

PubMed Central

Inflammatory bowel diseases (IBDs) are diseases that occur primarily in adolescence and early adult life. A second peak of IBD incidence occurs at the age of 50–80 years, while reports of first diagnosis after the age of 80 years are extremely rare. It is difficult to establish the true incidence of IBD in older patients due to problems of case definition, population, and particularly because it may be confused with other clinical conditions. A 91-year-old man was admitted to the Emergency Department with progressively worsening abdominal pain and 2–4 episodes of bloody diarrhea daily for the last month. Similar symptoms were not reported by the patient or his family during the past. Complete blood count and biochemical tests were normal, while stool examination showed erythrocytes and white blood cells. Pelvic CT showed inflammatory changes and loss of homogeneity in the perirectal fat together with considerable bowel wall thickening of both the rectum and sigmoid. Colonoscopy revealed edema, hyperemia and spontaneous friability, as well as microulcerations of the rectosigmoid mucosa. Tissue biopsies revealed histopathological lesions compatible with IBD. Finally the patient was treated with metronidazole, ciprofloxacin and mesalazine, with clear clinical improvement during the 5th day of treatment, and was finally discharged with almost normal stools. In conclusion, we report the case of first diagnosis of IBD in a 91-year-old man. The prevalence of IBD in patients aged >80 years is difficult to determine. Diagnostic tools are the same as for other age groups, but diagnosis may be difficult because there are a number of clinical conditions that may mimic IBD at this age. The treatment options are those used in younger patients, but special precautions should be taken. PMID:23341803

Koutsounas, Ioannis; Pyleris, Emmanouil; Karantanos, Panagiotis; Barbatzas, Charalambos

2012-01-01

323

First diagnosis of inflammatory bowel disease in a 91-year-old man.  

PubMed

Inflammatory bowel diseases (IBDs) are diseases that occur primarily in adolescence and early adult life. A second peak of IBD incidence occurs at the age of 50-80 years, while reports of first diagnosis after the age of 80 years are extremely rare. It is difficult to establish the true incidence of IBD in older patients due to problems of case definition, population, and particularly because it may be confused with other clinical conditions. A 91-year-old man was admitted to the Emergency Department with progressively worsening abdominal pain and 2-4 episodes of bloody diarrhea daily for the last month. Similar symptoms were not reported by the patient or his family during the past. Complete blood count and biochemical tests were normal, while stool examination showed erythrocytes and white blood cells. Pelvic CT showed inflammatory changes and loss of homogeneity in the perirectal fat together with considerable bowel wall thickening of both the rectum and sigmoid. Colonoscopy revealed edema, hyperemia and spontaneous friability, as well as microulcerations of the rectosigmoid mucosa. Tissue biopsies revealed histopathological lesions compatible with IBD. Finally the patient was treated with metronidazole, ciprofloxacin and mesalazine, with clear clinical improvement during the 5th day of treatment, and was finally discharged with almost normal stools. In conclusion, we report the case of first diagnosis of IBD in a 91-year-old man. The prevalence of IBD in patients aged >80 years is difficult to determine. Diagnostic tools are the same as for other age groups, but diagnosis may be difficult because there are a number of clinical conditions that may mimic IBD at this age. The treatment options are those used in younger patients, but special precautions should be taken. PMID:23341803

Koutsounas, Ioannis; Pyleris, Emmanouil; Karantanos, Panagiotis; Barbatzas, Charalambos

2012-09-01

324

Body Image Dissatisfaction in Male Cosmetic Surgery Patients  

Microsoft Academic Search

.   This study was the first empirical investigation of body image dissatisfaction in male cosmetic surgery patients. Thirty\\u000a men completed two body image measures prior to their initial consultation. Results were compared to the norms for each of\\u000a the measures and with a sample of 30 women seeking similar cosmetic procedures. Results indicated that patients did not demonstrate\\u000a greater dissatisfaction

Michael J. Pertschuk; David B. Sarwer; Thomas A. Wadden; Linton A. Whitaker

1998-01-01

325

[Clinical study of 62 patients with symptoms of male climacterium].  

PubMed

We prospectively reviewed the records of 62 patients who had sought evaluation at our hospital with a chief complaint of male climacteric symptoms. Late-onset hypogonadism (LOH)-related symptoms were evaluated during the initial visit based on the Aging Males' Symptoms (AMS) score, International Index of Erectile Function (IIEF) -5 score, and Center for Epidemiologic Studies Depression Scale (CES-D). Laboratory and endocrinologic testing, including the free testosterone (FT) level, was performed with blood samples collected before 10 : 00 am. The AMS psychological and CES-D scores in patients with a FT ?8.5 pg/ml were significantly higher than those in patients with a FT ?8.5 pg/ml. The study included 32 patients who were diagnosed with LOH (FT ?8.5 pg/ml) and treated with androgen replacement therapy (ART). The total, somatic, psychological, and sexual scores of the AMS were significantly decreased after the third intramuscular administration of testosterone enanthate; there were no serious complications. Because a significant proportion of depressed patients may be amongst the patients with aging male's symptoms, it is important to consider depression in the exclusion diagnosis during a clinical examination for LOH. PMID:23995524

Hori, Yasuhide; Nishii, Masahiko; Masui, Satoru; Yoshio, Yuko; Hasegawa, Yoshihiro; Kanda, Hideki; Yamada, Yasushi; Arima, Kiminobu; Sugimura, Yoshiki

2013-08-01

326

Benign osteoblastoma of the mandible in a 12-year-old female: A case report  

PubMed Central

Benign osteoblastoma refers to a benign tumor of the bone. Osteoblastoma most commonly affects the vertebrae and long tubular bones, however, in rare cases is observed in the facial bones. The current study presents the case of a 12-year-old female patient with a tumor in the mandibular body. Radiological imaging revealed a lesion with regular contours. The lesion was radically resected and histological analysis of the specimen demonstrated features that are typical of a benign osteoblastoma. The consequential defects of the jaw were reconstructed using titanium implants and autologous bone transplantation. The patient remains disease free subsequent to a five-month follow-up period. The aim of the present report is to present a rare case of benign osteoblastoma of the mandible. This study demonstrated that correct diagnosis and complete surgical excision are important to reduce the risk of recurrence of a benign osteoblastoma. PMID:25364451

MARDALEISHVILI, KONSTANTINE; KAKABADZE, ZURAB; MACHAVARIANI, AVTANDIL; GRDZELIDZE, TEIMURAZ; KAKABADZE, ANNA; SUKHITASHVILI, NATIA; KURASHVILI, TAMAR; SHONIA, NESTAN; MENABDE, GIORGI; ABIATARI, IVANE

2014-01-01

327

A new form of shoulder dysplasia in an 11-year-old boy  

PubMed Central

Pain and impaired function in the shoulder can result from a variety of conditions. Dysplasias of the shoulder girdle are usually asymptomatic; previous literature reports on shoulder malformation have focused on glenoid dysplasia or complete agenesis of the clavicle. We report the case of an 11 year old patient with severe shoulder pain after strenuous physical exercise. Physical inspection showed a prominent clavicle and anteriorly displaced humerus. X-ray demonstrated an abnormally shortened clavicle and a hypoplastic acromion; MRI imaging revealed an elongated deltoid muscle leading over the humeral head. The patient recovered with analgesics and careful mobilization. This is the first reported case of a dysplasia of both the acromion and the clavicle. This developmental abnormality can lead to significant pain, but apparently responds well to conservative treatment. It is possible that this condition is underdiagnosed or represents significantly delayed development.

Bichler, Jennifer; Arbogast, Martin; Krumrey-Langkammerer, Manuela; Hugle, Boris

2014-01-01

328

Fertility preservation strategies for male patients with cancer.  

PubMed

With the increasing number of patients surviving cancer, there is increasing interest in long-term quality of life, especially with respect to cancer-related infertility. Although infertility most commonly occurs as the result of treatment with gonadotoxic agents, it can also manifest before treatment has commenced. Current fertility preservation strategies for the postpubertal male patient with cancer focus on sperm cryopreservation before therapy. Sperm acquisition techniques should be discussed with the patient as early as possible, by either an oncologist or a specialist in male reproduction. For patients rendered infertile by cancer treatment who did not cryopreserve sperm beforehand, there are no techniques currently available to restore fertility. For the prepubertal male patient, cryopreservation of sperm is impossible. However, emerging research--primarily in animal models--into promising fertility preservation and restoration strategies might provide a clinical solution in the future. Advances in the protection and cryopreservation of spermatogonial stem cells (SSCs) might translate into clinical options for fertility preservation before treatment. Restoring fertility after treatment might also be possible via SSC autotransplantation or in vitro maturation of SSCs. Before any of these techniques become clinically viable, a number of scientific, logistical and ethical issues will need to be resolved. PMID:23835578

Katz, Darren J; Kolon, Thomas F; Feldman, Darren R; Mulhall, John P

2013-08-01

329

[Dental caries and dental erosion among 5- and 6-year old and 11- and 12-year old school children in the Hague, the Netherlands. Changing prevalences?  

Microsoft Academic Search

In 2002 a dental survey amongst 6- and 12-year-old schoolchildren in The Hague had been carried out. The 2002 survey suggested that in the period 1996-2002 the caries prevalence (% of cariesfree children) and the caries experience (mean dmfs\\/dmft scores) among 6-year-old children did not have changed significantly. Children of low socio-economic status in 2002 had an average higher dmfs\\/dmft

G. J. Truin; H. M. van Rijkom; J. Mulder; M. A. van't Hof

2004-01-01

330

Early attachment predicts emotion recognition at 6 and 11 years old  

Microsoft Academic Search

This paper reports on findings from a sample of 63 children at 6 years old, and 49 children at 11 years old, all from the same cohort who had been observed with mother in the Strange Situation at 1-year-old. At 6 and 11 years, the children responded to the task of providing verbal labels for line-drawn (caricatures of) emotion faces.

Howard Steele; Miriam Steele; Carla Croft

2008-01-01

331

Dental caries experience and tobacco use in 19-year-old Croatian army recruits.  

PubMed

The aim of this study is to investigate caries prevalence and smoking habit in the population of 19-year-old Croatian male recruits. Dental examination of 505 male recruits was conducted in 2001 in the military centre in Koprivnica. Caries status was described by the FS-T (Filled and Sound Teeth) index and DMFT (Decayed, Missing and Filled Teeth) index. Mean DMFT scores were 7.32 and FST 23.56. There was a significant statistical difference in comparison of smoking habits depending on the reason to visit the dentist (p = 0.001). The subjects who do not smoke tobacco have less decayed teeth (DT index with p < 0.001), and more teeth with fillings and/or sound teeth (FT with p = 0.005 and FST with p = 0.004). There is no statistically significant difference for the DMFT (p = 0.657) and MT (p = 0.703). In conclusion, it showed that FS-T is a more appropriate index for describing variation in the population with higher caries experience. In the population of Croatian recruits, there were an astonishing 58.6% of smokers. PMID:25145005

Badel, Tomislav; Pavicin, Ivana Savi?; Carek, Andreja Jelini?; Segovi?, Sanja

2014-06-01

332

Morphology of palatal rugae patterns among 5-15 years old children  

PubMed Central

Introduction: “The fibers running anteroposteriorly within the core and in concentric curves across the base of each ruga” determine their orientation and forms. The varying shapes of palatal rugae can be attributed to the fact that rugae develop as localized regions of epithelial proliferation and thickening. Fibroblasts and collagen fibers then accumulate in the connective tissue beneath the thickened epithelium and assume distinct orientation. Aim: The aim of the present study was to assess the morphology, gender difference of rugae pattern in 5-15 year old children. Materials and Methods: The various diagnostic dental stone cast available in Department of Pedodontics were analyzed by the method based on Thomas and Kotze classification in 1983. Results: There was a female prediction in the total count and primary rugae pattern. Comparing the shapes of rugae both in male and female study models showed a predominance in wave shape followed by cure. No circular pattern was observed in the study population. No statistical difference in the direction and unification of rugae among males and females. Conclusion: The fingerprint-like uniqueness of rugae to each individual has become accepted as a possible aid to person identification. This may help narrow the field for identification and give results in conjunction with the other methods such as visual, fingerprints, and dental characteristics in forensic sciences. PMID:23946575

Rajan, Vilvanathan Prabu; John, John Baby; Stalin, Ariudinambi; Priya, Geetha; Abuthagir, Abdul Kareem Syed

2013-01-01

333

Recurrent perioperative anaphylaxis in a 54-year-old man.  

PubMed

Reports suggest that perioperative anaphylaxis in patients undergoing general anesthesia range from 1 in 5000 to 1 in 20,000 with mortality rates as high as 9%. Because of the variety of medications that are used for general anesthesia and the rapid succession in which they are administered, it is often difficult to determine the etiology of a severe allergic episode in this setting. Antibiotics and anesthetics are notorious for precipitating allergic reactions and are often implicated. Other perioperative exposures and patient risk factors must also be considered. In this article, we describe the case of a patient who exhibited recurrent anaphylaxis episodes while trying to undergo a vital cardiac surgery. PMID:23883604

Franxman, Timothy J; Greenhawt, Matthew J; Baldwin, James L

2013-01-01

334

Distinct Molecular Phenotypes in Male and Female Schizophrenia Patients  

PubMed Central

Background In schizophrenia, sex specific dimorphisms related to age of onset, course of illness and response to antipsychotic treatment may be mirrored by sex-related differences in the underlying molecular pathways. Methodology/Principal Findings Here, we have carried out multiplex immunoassay profiling of sera from 4 independent cohorts of first episode antipsychotic naive schizophrenia patients (n?=?133) and controls (n?=?133) to identify such sex-specific illness processes in the periphery. The concentrations of 16 molecules associated with hormonal, inflammation and growth factor pathways showed significant sex differences in schizophrenia patients compared with controls. In female patients, the inflammation-related analytes alpha-1-antitrypsin, B lymphocyte chemoattractant BLC and interleukin-15 showed negative associations with positive and negative syndrome scale (PANSS) scores. In male patients, the hormones prolactin and testosterone were negatively associated with PANSS ratings. In addition, we investigated molecular changes in a subset of 33 patients before and after 6 weeks of treatment with antipsychotics and found that treatment induced sex-specific changes in the levels of testosterone, serum glutamic oxaloacetic transaminase, follicle stimulating hormone, interleukin-13 and macrophage-derived chemokine. Finally, we evaluated overlapping and distinct biomarkers in the sex-specific molecular signatures in schizophrenia, major depressive disorder and bipolar disorder. Conclusions/Significance We propose that future studies should investigate the common and sex-specific aetiologies of schizophrenia, as the current findings suggest that different therapeutic strategies may be required for male and female patients. PMID:24244349

Ramsey, Jordan M.; Schwarz, Emanuel; Guest, Paul C.; van Beveren, Nico J. M.; Leweke, F. Markus; Rothermundt, Matthias; Bogerts, Bernhard; Steiner, Johann; Bahn, Sabine

2013-01-01

335

Endoscopic papillary balloon dilation for a 7-year-old girl with choledocholithiasis.  

PubMed

A 7-year-old girl was referred to our hospital for severe abdominal pain and elevated serum levels of amylase and aminotransferase. Radiological examinations revealed choledocholithiasis. EPBD was performed under intravenous anesthesia using midazolam and ketamine chloride. After fluoroscopic confirmation of a bile duct stone, a dilation balloon (30 mm-long, 8 mm-diameter) was passed over the guidewire and placed across the papilla. The balloon was gradually inflated until the notch created by the papillary sphincter disappeared. At 4 atm, the notch disappeared and the pressure was maintained for 15 s. Stone extraction was performed by using a retrieval balloon catheter. Abdominal pain disappeared immediately after EPBD, and she resumed oral intake 2 days after EPBD. In conclusion, EPBD may be a safe and effective technique for the treatment of choledocholithiasis in pediatric patients. EPDB should be selected as a treatment for pediatric choledocholithiasis in view of its advantages of preserving papillary function. PMID:23679173

Sogo, Tsuyoshi; Kondo, Takeo; Tsunoda, Tomoyuki; Murayama, Akitoshi; Komatsu, Haruki; Inui, Ayano; Fujisawa, Tomoo

2013-04-01

336

Chronic recurrent multifocal osteomyelitis in a 13 year old female athlete: a case report  

PubMed Central

Chronic recurrent mutlifocal osteomyelitis (CRMO) is an extremely rare skeletal disorder in the younger population. It presents with multifocal bony lesions that often mimic more sinister diagnoses such as infection or neoplasm. The cause of this condition remains unknown and there is limited evidence on effective treatments. In this case, a 13-year-old female athlete presented to a sports chiropractic clinic with non-traumatic onset of right ankle pain. After failed conservative management, radiographs and MRI were obtained exhibiting a bony lesion of the distal tibia resembling osteomyelitis. The patient was non-responsive to antibiotics, which lead to the diagnosis of CRMO. CRMO should be considered as a differential diagnosis for chronic bone pain with affinity for the long bones of the lower extremity in children and adolescents. The role of the primary clinician in cases of CRMO is primarily that of recognition and referral for further diagnostic investigations. PMID:24302781

Ferguson, Brad; Gryfe, David; Hsu, William

2013-01-01

337

A 60-year-old woman with mild memory impairment: review of mild cognitive impairment.  

PubMed

Many older individuals experience or demonstrate cognitive impairment that is significantly abnormal for their age and education yet beneath the threshold for a diagnosis of dementia. This mild cognitive impairment causes minimal functional impairment and is often overlooked in clinical settings, yet affected individuals are at heightened risk for a range of adverse outcomes including conversion to dementia. The case of Ms E, a 60-year-old woman with mild memory impairment and white matter lesions on magnetic resonance imaging, provides an opportunity to consider the questions that face patient, family, and clinicians when mild cognitive symptoms prompt a search for diagnosis and management options. Discussion of her case reviews mild cognitive impairment with emphasis on an evidence-based approach to evaluation and treatment, including management of comorbid medical conditions, lifestyle changes, and pharmacotherapy. PMID:18768403

Ellison, James M

2008-10-01

338

Fatal childhood calciphylaxis in a 10-year-old and literature review.  

PubMed

Calciphylaxis is a rare but highly morbid disorder of vascular calcification and skin necrosis, affecting 1% to 4% of adults with end-stage renal disease. Only three affected children have previously been described. We report an unusual instance of fatal calciphylaxis involving a 10-year-old boy, in the setting of sarcoidosis-induced end-stage renal disease. A review of pediatric calciphylaxis cases suggests: (a) increased risk in boys with end-stage renal disease and secondary hyperparathyroidism; (b) frequent distal extremity and visceral organ involvement, (c) worse prognosis with acral necrosis, and (d) possible increased resistance to medical treatment compared to adult patients. Hyperesthetic pain is a common sentinel symptom, and soft tissue x-rays or xeroradiography or both may aid in the diagnosis of pediatric calciphylaxis. Parathyroidectomy in combination with supportive medical management may be the best treatment option in stopping the progression of disease in the pediatric population. PMID:16780477

Feng, Jing; Gohara, Mona; Lazova, Rossitza; Antaya, Richard J

2006-01-01

339

2,8-Dihydroxyadenine renal stones in a 41-year-old man.  

PubMed

A case is presented of a 41-year-old man with a history of recurrent renal stones over 10 years. Analysis of the stone showed that, although it gave a positive reaction with the non-specific phosphotungstic acid test, uricase failed to identify any urate present. Analysis in a reference laboratory confirmed its composition as dihydroxyadenine. Patients who are homozygous for the rare autosomal-recessive adenine phosphoribosyltransferase deficiency, excrete large amounts of 2,8-dihydroxyadenine, which has poor solubility at normal urinary pH. Treatment with the xanthine oxidase inhibitor allopurinol induces a total cessation of stone formation. Increased awareness of the condition and knowledge of the limitations of some methods of laboratory analysis for renal stones should help to identify this type of stone and prevent renal damage. PMID:15025810

Wilkinson, Hazel; Samuell, Colin; Stower, Michael

2004-03-01

340

Pesticide-induced quadriplegia in a 55-year-old woman.  

PubMed

Acephate is a commercial organophosphate pesticide formerly used in households and now used primarily for agriculture. Poisoning symptoms include salivation, lacrimation, urination, defecation, gastrointestinal illness, and emesis. In addition to these classic symptoms, neurodegeneration can result from increased and continued exposure of organophosphates. This 55-year-old woman presented with organophosphate-induced delayed neuropathy in the form of quadriplegia due to the commonly used pesticide acephate. She was exposed to this pesticide through multiple sprayings in her work office with underrecognized poisoning symptoms. She presented to her primary care physician with neuropathic pain and paralysis in her arm following the sprayings and eventual complete paralysis. The patient lived for 2 years following her toxic exposure and quadriplegia. A complete autopsy after her death confirmed a transverse myelitis in her spinal cord. We conclude that in susceptible individuals, acephate in excessive amounts can produce severe delayed neurotoxicity as demonstrated in animal studies. PMID:25354225

Beavers, Charles T; Parker, Joseph J; Flinchum, Dane A; Weakley-Jones, Barbara A; Jortani, Saeed A

2014-12-01

341

Osteogenesis imperfecta presenting as aneurysmal subarachnoid haemorrhage in a 53-year-old man  

PubMed Central

The authors describe a case of aneurysmal subarachnoid haemorrhage in a 53-year-old man with background of osteogenesis imperfecta (OI). CT brain revealed diffuse subarachnoid haemorrhage (SAH) and cerebral angiogram subsequently confirmed vertebral artery aneurysm rupture leading to SAH. To the authors knowledge this is the first case of vertebral artery aneurysmal SAH described in OI. A previously undiagnosed OI was confirmed by genetic analysis (COL1A1 gene mutation). This aneurysm was successfully treated by endovascular route. Post interventional treatment patient developed stroke secondary to vasospasm. Communicating hydrocephalus, which developed in the process of management, was successfully treated with ventriculo-peritoneal shunt. The aetio-pathogenesis and management of this condition is described. The authors have reviewed the literature and genetic basis of this disease. PMID:22674700

Kaliaperumal, Chandrasekaran; Walsh, Tom; Balasubramanian, Chandramouli; Wyse, Gerry; Fanning, Noel; Kaar, George

2011-01-01

342

Hyperimmunoglobulin E Syndrome Presenting as Osteogenesis Imperfecta in a 3 Year Old Child  

PubMed Central

We present a case of hyperimmunoglobulin E (hyper-IgE) syndrome in a three year old boy. There are many pitfalls in diagnosing this disease in the very young population, mainly due to the ambiguity of some diagnostic criteria in this population. Recognizing this syndrome early in life can potentially be very beneficial to the patients involved and the medical system as a whole. Early diagnosis can lead to fewer diagnostic tests, fewer referrals, and more focused exams, thus potentially reducing medical cost while also reducing the number of serious infections later in life, including those which are potentially fatal. Additionally, a wellknown association between lymphoma and hyper-IgE syndrome has been established; while no recommendations are currently in place for screening, early diagnosis could help medical providers have a higher threshold for diagnosis of this disease. PMID:24470957

Gorgas, Stephen; Abuhammour, Walid; Blackwood, R. Alexander

2013-01-01

343

Pulmonary veno-occlusive disease in an 11-year-old girl: diagnostic pitfalls.  

PubMed

Pulmonary veno-occlusive disease (PVOD) is a rare chronic lung disease that is difficult to diagnose due to non-specific clinical findings. Little is known about the pathogenesis of PVOD. Reported herein is the case of an 11-year-old girl who initially presented with 'bat-wing' shadows on chest radiography. This finding, coupled with prominent hemosiderosis in bronchoalveolar lavage fluid, initially led to a misdiagnosis of idiopathic pulmonary hemosiderosis. Oral prednisolone dramatically improved signs and symptoms initially, but her condition then gradually deteriorated during maintenance therapy with corticosteroids and other immunosuppressants. PVOD was suspected but not confirmed owing to a lack of hallmark radiographic findings and contraindications for lung biopsy. Three years later, while arranging for lung transplantation, the patient experienced sudden onset of fatal massive pulmonary edema. PVOD was confirmed at autopsy. This case provides insights regarding an unfamiliar presentation of PVOD and may help physicians to avoid diagnostic pitfalls. PMID:24548200

Kano, Gen; Nakamura, Keiko; Sakamoto, Izumi

2014-02-01

344

Postintubation tracheal stenosis in an 11-year-old boy: a surgical and anaesthetic challenge.  

PubMed

We present a case of postintubation tracheal stenosis in an 11-year-old boy occurring after a relatively short period of intubation. He had been intubated and ventilated in a paediatric intensive care unit after a road traffic accident. Clinical symptoms manifested by oxygen desaturation and wheeziness, finally leading to deterioration of the level of consciousness, occurred a few hours after the first attempt at extubation after 48 h requiring reintubation. Endoscopic examination performed a few weeks later revealed a tracheal stenosis. Consequently, he underwent an initial period of conservative treatment consisting of balloon dilatation and intralesional injection of steroids, followed by a tracheal resection and reconstruction. The anaesthetic management of patients with tracheal stenosis presenting for laryngo-tracheobronchoscopy and balloon dilatation is discussed. PMID:12472713

Aguilera, I M; Walker, R W M; Dearlove, O R

2002-10-01

345

Pleomorphic Adenoma of Minor Salivary Gland in a 14 year Old Child.  

PubMed

Salivary gland tumours are rare in childhood, and almost all of them occur in parotid gland. Minor salivary gland tumours are even rarer, pleomorphic adenoma being the most frequently found tumour. Only seventeen cases of pleomorphic adenoma arising in the minor salivary gland tumour have been reported in children and adolescents. Pleomorphic adenoma of minor salivary gland represents about 45% of all the tumours of the minor salivary glands. Pleomorphic adenoma is slowly enlarging tumour indistinguishable from adenoid cystic carcinoma clinically, except for pain and ulceration, which is more common in the latter. Carcinoma arising from pleomorphic adenoma has been reported in 3% cases amongst the minor salivary gland tumours. This report presents a case of pleomorphic adenoma of minor salivary gland in a 14 year old female patient with a brief review of literature. PMID:24431845

Pramod Krishna, B

2013-06-01

346

Laparoscopic treatment for torsion of the gallbladder in a 7-year-old female.  

PubMed

A 7-year-old girl was diagnosed with viral enteritis and was admitted to our hospital. Sudden right upper quadrant tenderness appeared 2 days after admission. Ultrasonography revealed a large thick-walled cystic gallbladder and an inflammation-induced hyperechoic cystic duct. The long axis of the gallbladder was in a horizontal rather than a vertical alignment. Computed tomography demonstrated a markedly enlarged gallbladder with a slightly thickened wall and an enhanced twisted cystic pedicle. The diagnosis of gallbladder torsion led to laparoscopic detorsion and cholecystectomy. The gallbladder was gangrenous and was rotated counterclockwise with the attachment of the mesentery to the inferior surface of the liver. Although it occurs more rarely in children than in adults, torsion of the gallbladder must be considered in the differential diagnosis of an acute abdomen. Early diagnosis and immediate laparoscopic intervention can help to achieve an excellent patient outcome. PMID:19793492

Matsuda, Akihisa; Sasajima, Koji; Miyamoto, Masayuki; Maruyama, Hiroshi; Yokoyama, Tadashi; Suzuki, Seiji; Matsutani, Takeshi; Sugiura, Atsushi; Yanagi, Ken; Matsushita, Akira; Arai, Hiroki; Tajiri, Takashi

2009-01-01

347

Multiple Brain Tuberculomas in a 32-year-old Woman with Chronic Headache.  

PubMed

Tuberculosis (TB) has re-emerged in the two past decades as a major health problem worldwide. Presently, more than 2 billion people (one third of the world population) are infected with TB, of which approximately 10% will develop the clinical disease. The incidence of central nervous system (CNS) TB is related to the prevalence of TB in the community, and it is still the most common type of chronic CNS infection in developing countries. We describe a 32-year-old woman, who presented with chronic headache, followed by gaze palsy and decreased level of consciousness. The disease was diagnosed through TB PCR of the cerebrospinal fluid (CSF). Anti TB drugs and corticosteroid were started for her and she responded successfully to treatment. We conclude that TB of CNS should be considered in patients with chronic headache, particularly in endemic regions because its diagnosis may be missed. PMID:25305774

Ahmadi, Fatemeh; Nashibi, Roohangiz; Naghieh, Masih; Feizi, Jalil; Shirmardi, Mohammad

2014-10-01

348

A 46-year-old woman with left shoulder pain and worsening dyspnea.  

PubMed

A 46-year-old woman presented with worsening dyspnea and palpitations for 3 days following an episode of left shoulder pain. The patient had received a diagnosis of patent ductus arteriosus with Eisenmenger syndrome in childhood but had been inconsistently taking digoxin and diuretics since then. She was married but had never been pregnant. Over the previous 2 to 3 years, her exercise capacity had decreased significantly, with frequent episodes of near syncope and chest pain. She had developed bilateral leg edema. Three days prior to admission, she noticed an episode of severe, sharp pain in her left shoulder that was nonradiating but associated with palpitations and sweating and that lasted for about 20 min. The shoulder pain subsided spontaneously but her dyspnea worsened significantly, which prompted her to present to the ED. PMID:25180748

Liu, Shuang; Li, Xiaoyun; Huang, Xiaoyong; Li, Tiezheng; Yang, Ya; Qiao, Renli

2014-09-01

349

A Doctor Talks to 9-to-12-Year Olds.  

ERIC Educational Resources Information Center

As a part of a series of books written by physicians for their patients, this publication explains heredity, birth, and growth patterns to pre-teen children. The chapters are written in language appropriate for children moving from childhood into their teens and deal with topics like: cells, conception, prenatal development, puberty, and changing…

Larrigo, Marion O.; Cassidy, Michael A.

350

A Doctor Talks to 5-to-8-Year Olds.  

ERIC Educational Resources Information Center

One of a series of books written by doctors for their patients, this publication gives information about life in casual and straightforward children's language. Birds, fish and other animals are compared to humans and are used as examples to explain conception, birth and the development of babies to adulthood. To illustrate important concepts,…

Meilach, Dona Z.; Mandel, Elias

351

Improvements in Behavioral Symptoms following Antibiotic Therapy in a 14-Year-Old Male with Autism  

PubMed Central

This case report describes the benefits of antibiotic and antifungal therapy on behavior in a child with autism undergoing treatment for encopresis. Over the course of treatment, the child exhibited a reduction in aberrant behaviors, increased gastrointestinal function, and improved quality of life. PMID:23853732

Ramirez, P. Lucas; Barnhill, Kelly

2013-01-01

352

Tattoos on 18-year-old male adolescents - Characteristics and associated factors*  

PubMed Central

BACKGROUND Prevalence of tattoos is around 10-26% in men and 10-22% in women, and can involve negative effects such as: regret, removal attempts, physical and biological changes of the skin and association with some viral diseases. OBJECTIVE to determine the prevalence, characteristics and factors associated with tattoos in recruiters joining the military. METHODS the recruiters were examined by dermatologists that documented the presence or absence of tattoos, as well as their sizes, colors, designs and patterns, and whether they needed a parent's consent to get a tattoo. RESULTS 1,968 recruiters were examined and the prevalence of tattoos was 10.82% (213), 141 (66.20%) had a single tattoo, 44 (20.66%) two tattoos, 15 (7.04%) three tattoos, 9 (4.23%) four tattoos, and 4 (1.88%) had more than four. Of the total sample, 168 (80.77%) reported getting the first tattoo before the age of 18. 158 (74.53%) were monochromatic. In relation to size, 108 (50.70%) had tattoos of up to 10 cm, 75 (35.21%) had tattoos measuring between 11-20cm, while 30 had ones over 21cm (14.09%). CONCLUSIONS The population studied had a high prevalence of tattoos for their age, the percentage of complex (large and polychromatic) tattoos was also high. PMID:24474101

Bicca, Jose Froner; Duquia, Rodrigo Pereira; Breunig, Juliano de Avelar; de Souza, Paulo Ricardo Martins; de Almeida Jr., Hiram Larangeira

2013-01-01

353

Case Report: 16-Year-Old Male with Autistic Disorder with Preoccupation with Female Feet  

ERIC Educational Resources Information Center

This paper highlights clinical challenges faced when diagnosing and then treating an individual presenting to a child and adolescent psychiatry clinic because of unwelcome comments he made to female peers about their feet. Novel use of exposure therapy helped him effectively decrease his comments from 1 to 2 times per month to once every 6 months.…

Early, Maureen C.; Erickson, Craig A.; Wink, Logan K.; McDougle, Christopher J.; Scott, Eric L.

2012-01-01

354

Case report: 16-Year-old male with autistic disorder with preoccupation with female feet.  

PubMed

This paper highlights clinical challenges faced when diagnosing and then treating an individual presenting to a child and adolescent psychiatry clinic because of unwelcome comments he made to female peers about their feet. Novel use of exposure therapy helped him effectively decrease his comments from 1 to 2 times per month to once every 6 months. Conceptualizing this case as the individual's failed attempts toward relationships with females instead of sexual harassment led to diminution of problematic behavior. Implications for diagnosis and treatment of individuals with Autistic Disorder displaying problematic behaviors are presented. PMID:21818675

Early, Maureen C; Erickson, Craig A; Wink, Logan K; McDougle, Christopher J; Scott, Eric L

2012-06-01

355

A 17YearOld Competitive Soccer Player with Pre-excitation Pattern on 12Lead ECG  

Microsoft Academic Search

The patient was a 17-year-old soccer player. He played competitive, non-professional, soccer in a regional league, with 1\\u000a or 2 matches per week and 2 additional training sessions of 2?h each. He was seen elsewhere for a first screening evaluation.\\u000a His exercise capacity was unrestricted. There were no familial cases of sudden death or known cardiac disease. He had no

Hein Heidbüchel

356

Progressive cerebellar ataxia, spasticity, psychomotor retardation, and hexosaminidase deficiency in a 10-year-old child: juvenile Sandhoff disease.  

PubMed

During the course of investigating a 10-year-old boy because of progressive deterioration of intellectual functioning, ataxia, and hemiplegia, an absence of serum hexosaminidase activity was noted. A skin biopsy examined by electron microscopy showed axonal accumulations of dense osmiophilic deposits. Because of the patient's age at onset and the slowly progressive nature of his ilness, we are reporting an atypical juvenile case of Sandhoff disease. PMID:559267

MacLeod, P M; Wood, S; Jan, J E; Applegarth, D A; Dolman, C L

1977-06-01

357

Aicardi-Goutières Syndrome and Systemic Lupus Erythematosus (SLE) in a 12YearOld Boy With SAMHD1 Mutations  

Microsoft Academic Search

Aicardi-Goutières syndrome is an early-onset encephalopathy with a presumed immune pathogenesis caused by inherited defects in nucleic acid metabolism. The clinical picture resembles a congenital viral infection despite negative investigations for common viruses. In addition to leukoencephalopathy with calcifications of basal ganglia, patients show increased levels of the antiviral cytokine interferon-? in cerebrospinal fluid. We report on a 12-year-old boy

Georgia Ramantani; Martin Häusler; Pascal Niggemann; Britta Wessling; Hedwig Guttmann; Michael Mull; Klaus Tenbrock; Min Ae Lee-Kirsch

2011-01-01

358

Acute coronary syndrome in a 100-year-old woman treated successfully with primary percutaneous coronary angioplasty  

PubMed Central

We present a case of a 100-year-old woman living alone with ST-elevation myocardial infarction acute coronary syndrome of the infero-lateral wall treated with percutaneous coronary intervention. Coronary angiography revealed critical 99% stenosis in the marginal branch of the circumflex artery and insignificant lesions in other arteries. Two bare metal stents were implanted successfully in the same session. The patient was discharged home in good general condition, able to live and function independently. PMID:24570714

Beckowski, Maciej; Szwed, Hanna; Ciszewski, Andrzej

2013-01-01

359

Prolonged QT Syndrome in a 27-Year-Old Female Presenting as a Cardiac Arrest after Elective Surgery  

PubMed Central

Cardiac arrest is a true medical emergency and clinicians should base the management on American Heart Association advanced cardiac life support algorithm. The potential triggers of cardiac arrest should be sought. We present a case of a 27-year-old female who developed cardiac arrest and was later found to have congenital long QT syndrome. The patient's outcome was favorable. Discussion of the key management options will be discussed in the text.

Mirrakhimov, Aibek E.; Voore, Prakruthi; Ali, Alaa M.

2014-01-01

360

74-year-old man with left main and carotid artery disease - how life can change plans  

PubMed Central

An unexpected incident or rapid deterioration of a patient's condition may require optimal adaptation of the treatment to the current state of the patient. We present a case of a 74-year-old man with significant left main coronary artery stenosis and tight stenoses of both carotid arteries. The case was initially qualified for bypass grafting with accompanying carotid artery endarterectomy, but an unexpected accident changed our way of treatment. Three days after angiography the patient suffered an ischemic stroke. We held a multidisciplinary meeting of the “Neuro-Vascular-Heart Team” and decided to treat the patient percutaneously. PMID:24570726

Ilnicki, Dawid; Telichowski, Artur; Reczuch, Krzysztof

2013-01-01

361

Megaloblastic hematopoiesis in a 20 year old pregnant female  

PubMed Central

Summary Background: Nitrous oxide can cause disordered blood cell proliferation and lead to pancytopenia and altered immune function. Case Report: A young pregnant female patient presented after binge nitrous oxide abuse with altered mental status and abnormal vital signs. From her initial assessment she was noted to have pancytopenia and was found to have megaloblastic, hyper-cellular changes in a subsequent bone marrow biopsy. This presentation was determined to be secondary to toxic effects after heavy use of nitrous oxide. Conclusions: Nitrous oxide exposure, including use as an inhalant, over 12 hours can lead to bone marrow abnormalities such as megaloblastic hematopoiesis. PMID:23569553

Trivette, Evan T.; Hoedebecke, Kyle; Berry-Caban, Cristobal S.; Jacobs, Brandy R.

2013-01-01

362

A 17 year old with isolated proximal tibiofibular joint arthritis  

PubMed Central

The proximal tibiofibular joint (TFJ) is rarely affected in rheumatic diseases, and we frequently interpret pain of the lateral knee as the result of overuse or trauma. Nonetheless, the TFJ is a synovial joint that communicates with the tibiofemoral joint in a proportion of patients. While proximal TFJ arthritis has been rarely associated with existing spondyloarthritis, isolated TFJ arthritis as the presenting manifestation of spondyloarthritis has not yet been described. Here, we report the clinical and radiographic presentation of an adolescent with chronic proximal TFJ arthritis heralding spondyloarthritis highly suggestive of ankylosing spondylitis. PMID:23302539

2013-01-01

363

Intratentorial osteochondrolipoma in a 9-year-old boy.  

PubMed

Intracranial osteolipomas and chondromas are rare benign tumors. Forty-five chondromas, mostly supratentorial, have been reported in the literature since 1981, with origins most commonly in the sellar regions. Twenty-one osteolipomas have been described to date, usually located near the tuber cinereum or the corpus callosum. The authors present a case of an osteochondrolipoma arising from the tentorium diagnosed in a pediatric patient at the age of 9 years. The case and treatment are discussed, and a review of the literature is provided. PMID:19409017

Ahmadi, Sebastian A; van Landeghem, Frank K H; Blechschmidt, Cristiane; Lieber, Kerstin; Haberl, Ernst-Johannes; Thomale, Ulrich-Wilhelm

2009-05-01

364

Fatality Assessment and Control Evaluation (FACE) for Wisconsin: A 20 Year Old Farmer Dies After Entering a Silo Recently Filled with Haylage.  

National Technical Information Service (NTIS)

A 20 year old white male college student who worked and lived on the family farm, died while working for a neighbor filling silo. This was the worker's fourth day at work, the farm had been in operation for 29 years. A load of fresh chopped haylage had be...

1993-01-01

365

Mamontovaya Kurya: an enigmatic, nearly 40 000 years old Paleolithic site  

E-print Network

Mamontovaya Kurya: an enigmatic, nearly 40 000 years old Paleolithic site in the Russian Arctic). This site, radiocarbon dated to 35-40 000 years BP, is believed to represent the oldest reported evi- dence an updated documentation of the 109 MAMONTOVAYA KURYA: AN ENIGMATIC, NEARLY 40 000 YEARS OLD PALEOLITHIC SITE

Ingólfsson, �lafur

366

Auditory-Motor Learning during Speech Production in 9-11-Year-Old Children  

E-print Network

Auditory-Motor Learning during Speech Production in 9- 11-Year-Old Children Douglas M. Shiller1 of speaking ability remain poorly understood. Auditory feedback during speech production is believed to play: In the present study, we manipulated auditory feedback during speech production in a group of 9�11-year old

367

STATIC AND FATIGUE PERFORMANCE OF 40 YEAR OLD PRESTRESSED CONCRETE GIRDERS STRENGTHENED WITH VARIOUS CFRP SYSTEMS  

E-print Network

STATIC AND FATIGUE PERFORMANCE OF 40 YEAR OLD PRESTRESSED CONCRETE GIRDERS STRENGTHENED program aimed at investigating the static and fatigue behavior of 40 year old prestressed concrete bridge fatigue loading conditions. The girders were taken from a decommissioned bridge erected in 1961. Two

368

The Semiotic Landscape and 3-Year-Olds' Emerging Understanding of Multimodal Communication Practices  

ERIC Educational Resources Information Center

This article considers the impact of the increasing use of the visual mode in texts found in urban landscapes on two 3-year-olds' understanding of communication practices. The data discussed are taken from a study into a group of 3- to 6-year-olds' interaction with and emerging comprehension of the visual mode and its connection to…

Yamada-Rice, Dylan

2014-01-01

369

Five- to Twelve-Year-Olds' Control of Movement Velocity in a Dynamic Collision Avoidance Task  

ERIC Educational Resources Information Center

We investigated age-related differences in a dynamic collision avoidance task that bears a resemblance to pedestrian road crossing. Five- to seven-year-old children, ten- to twelve-year-old children and adults were instructed to push a doll across a small-scale road between two toy vehicles, which approached one after the other. We analysed the…

te Velde, Arenda F.; van der Kamp, John; Savelsbergh, Geert J. P.

2008-01-01

370

Four- and Six-Year-Olds Use Pragmatic Competence to Guide Word Learning  

ERIC Educational Resources Information Center

The present study investigates whether four- and six-year-old children use pragmatic competence as a criterion for learning from someone else. Specifically, we ask whether children use others' adherence to Gricean maxims to determine whether they will offer valid labels for novel objects. Six-year-olds recognized adherence to the maxims of…

Vazquez, Maria D.; Delisle, Sarah S.; Saylor, Megan M.

2013-01-01

371

Oral spironolactone therapy in male patients with rosacea.  

PubMed

Spironolactone at 50 mg/day was orally administered for four weeks to 13 male patients with rosacea in order to observe its clinical effectiveness. Serum estradiol (E2), 17OH-progesterone (17OH-P4), testosterone (T), androstenedione (delta 4 A), dihydrotestosterone (DHT), dehydro-epiandrosterone sulfate (DHEA-S) were measured prior to and after treatment. Although there were no significant changes in T, delta 4A, DHT, or DHEA-S, the serum levels of 17OH-P4 increased significantly. E2 tended to increase, although the change was not significant. Two of the 13 patients discontinued spironolactone treatment because of general malaise, but seven of the remaining eleven patients exhibited an improvement in their rosacea. These findings demonstrate that a low dose of spironolactone is effective in the treatment of rosacea in some male patients and suggest that it is possible that changes in the metabolism of sex steroid hormones such as cytochrome p-450 isozymes have some bearing on the etiology of rosacea. PMID:1386614

Aizawa, H; Niimura, M

1992-05-01

372

A 24-year-old Ethiopian farmer with burning feet.  

PubMed

Podoconiosis is a non-infectious tropical disease caused by exposure of bare feet to irritant alkalic clay soils. This causes an asymmetrical swelling of the feet and lower limbs due to lymphoedema. This swelling is called "elephantiasis" and may lead to severe disability of the patient. It is found in areas of tropical Africa, Central and South America and north-west India, where such soils coexist with high altitude, high seasonal rainfall and low income. Social stigmatization of people with the disease is widespread and economic losses are enormous. Podoconiosis is unique in being an entirely preventable non-communicable tropical disease. However, so far it has received little attention from health care policy makers. PMID:23042845

Visser, Benjamin Jelle; Korevaar, Daniel Arnoldus; van der Zee, Janneke

2012-10-01

373

Forty-Year-Old Foam Springs Back With New Benefits  

NASA Technical Reports Server (NTRS)

The most recognized and widely used NASA spinoff is at it again. Temper foam, whose origins date back to 1966 when it was developed to absorb shock and, thus, offer improved protection and comfort in NASA s airplane seats, has paid its dividends to Earth repeatedly, and in many different ways. It has padded the helmets of the Dallas Cowboys throughout the 1970s and 1980s, protected bedridden patients from bedsores, and comforted the feet of thousands wearing stylish shoes that incorporate the cushioning material in their insoles. Four decades later, the world has come to realize that there are no bounds to temper foam s benefits. Though the rights to the technology have been shared amongst various manufacturers, the original product maker is still going strong, pushing temper foam into new arenas, including automotives, amusement parks, prosthetics, and modern art.

2005-01-01

374

Initial Hospital / Hospice Care and Discharge on Same Day A 92 year old female has been in the hospital for 2 weeks, her health is deteriorating and the  

E-print Network

Initial Hospital / Hospice Care and Discharge on Same Day A 92 year old female has been in the hospital for 2 weeks, her health is deteriorating and the decision was made to transfer the patient to hospice care. The patient will not be moving from her hospital room; just the status of the patient has

Oliver, Douglas L.

375

Elective laparoscopic cholecystectomy in a 75-year-old woman with situs viscerum inversus totalis  

PubMed Central

Situs viscerum inversus totalis is a rare disorder presenting with complete transposition of thoracic and abdominal viscera. It is associated with certain organ anomalies, but it is not a predisposing factor to cholecystolithiasis. To date, fewer than 100 cholecystectomies in patients with situs inversus have been published worldwide. We report a case of a 75-year-old woman referred to our hospital with abdominal pain in the left hypochondrium. Situs inversus totalis and acute calculous cholecystitis were diagnosed and successfully conservatively treated with antibiotics. The patient underwent elective laparoscopic cholecystectomy 3 months later. The procedure and postoperative course were uneventful and the patient recovered well. The clinical presentation of these patients with cholecystolithiasis may be confusing and vague and the correct diagnosis delayed. Laparoscopic cholecystectomy is the gold standard in the treatment even though the operation requires some modifications in operating theatre arrangement and position of the surgical team. Most surgeons are right-handed, and to operate laparoscopically in the “mirror image” anatomical situation using mainly the left hand for dissection may be stressful, uncomfortable and more time-consuming. Some recommendations to overcome this issue have been published. In conclusion, the above-mentioned anomaly may cause some risk and delay of the exact diagnosis, but it is not dangerous in itself. Laparoscopic cholecystectomy is a safe procedure, even in the case of acute cholecystitis, if performed by an experienced laparoscopic surgeon. The most dangerous is always an incautious and too self-confident surgeon. PMID:23256031

Hoffmann, Petr; Koci, Jaromir

2012-01-01

376

The prevalence of middle ear diseases among 7- to 13-year-old primary school students in Yozgat province.  

PubMed

External and/or middle ear pathologies are commonly encountered by otolaryngologists, family practitioners and pediatricians. If left undiagnosed, these conditions may result in significant irreversible damage such as varying degree of hearing loss that can affect the social or professional performance of the individuals in later stages of life. In this study, we aimed to investigate the prevalence of several external and/or middle ear diseases among 7-13-year-old primary school students in Yozgat province. The province of Yozgat serves as a transition point between the Central Anatolian and Black Sea regions of Turkey. Nine hundred and seventy-eight primary school students were included in the study between March 1, 2012 and March 15, 2012. All subjects underwent a routine ear examination in school with a diagnostic otoscope. The students with pathologic ear findings were further evaluated to identify the underlying process. The age range of 978 students (527 males, 451 females) was 7 to 13 (mean: 10.5) years. Tympanic membrane (TM) pathology was detected in 33 (3.37%) of the cases overall. Of the cases, 3 (0.30%) had TM perforation, 11 (1.12%) had myringosclerosis (MS), 13 (1.32%) had serous otitis media, 1 (0.10%) had atresia of the left ear, and 4 (0.40%) had retraction pocket. One patient (0.10%) had undergone a left cochlear implantation procedure. The results of our study seem to be comparable with the other studies reported in the literature. Routine periodic ear examinations during the primary school ages are mandatory to obtain the exact prevalence of these pathologies in the entire population. We believe that early childhood screening of middle ear disease will have a positive effect on treatment. PMID:23427512

Ozkiri?, Mahmut; Kapusuz, Zeliha; Saydam, Levent

2012-01-01

377

Initial diagnosis of HIV/AIDS in a 56-year-old man with non-healing forearm lesion  

PubMed Central

SUMMARY A 56-year-old Hispanic man with no significant medical problems presented with a 2-month history of a non-healing right forearm lesion that progressed despite several courses of empiric antibiotics. The patient underwent incision and drainage. Warthin-Starry stain with immunohistochemistry testing diagnosed bacillary angiomatosis secondary to Bartonella quintana. Subsequently, the patient was diagnosed with HIV, with a CD4 count of 68 cells/mm3, and a HIV viral load of 47, 914 copies/mL. The patient was treated with doxycycline and started on antiretroviral therapy. The lesion has resolved and he has had no recurrence after 16 months of treatment. PMID:24248316

Zapata, Heidi J; Villanueva, Merceditas; Shenoi, Sheela

2014-01-01

378

Initial diagnosis of HIV/AIDS in a 56-year-old man with non-healing forearm lesion.  

PubMed

A 56-year-old Hispanic man with no significant medical problems presented with a 2-month history of a non-healing right forearm lesion that progressed despite several courses of empiric antibiotics. The patient underwent incision and drainage. Warthin-Starry stain with immunohistochemistry testing diagnosed bacillary angiomatosis secondary to Bartonella quintana. Subsequently, the patient was diagnosed with HIV, with a CD4 count of 68 cells/mm(3), and a HIV viral load of 47, 914 copies/mL. The patient was treated with doxycycline and started on antiretroviral therapy. The lesion has resolved and he has had no recurrence after 16 months of treatment. PMID:24248316

Zapata, Heidi J; Villanueva, Merceditas; Shenoi, Sheela

2013-01-01

379

From coitus to concurrency: sexual partnership characteristics and risk behaviors of 15-19 year old men recruited from urban venues in Tanzania  

PubMed Central

Understanding the uptake and patterns of sexual partnerships of adolescent males reveals their risky behaviors that could persist into adulthood. Using venue-based sampling, we surveyed 671 male youth ages 15–19 from an urban Tanzanian neighborhood about their sexual partnerships during the past six months. The proportion of males who had ever had sex increased with age (21% at age 15; 70% at age 17; 94% at age 19), as did the proportion who engaged in concurrency (5% at age 15; 28% at age 17; 44% at age 19). Attendance at ?2 social venues per day and meeting a sexual partner at a venue was associated with concurrency. Concurrency was associated with alcohol consumption before sex among 18–19 year olds and with not being in school among 15–17 year olds. We find that concurrency becomes normative over male adolescence. Venue-based sampling may reach youth vulnerable to developing risky sexual partnership patterns. PMID:22990763

Yamanis, Thespina J.; Doherty, Irene A.; Weir, Sharon S.; Bowling, James M.; Kajula, Lusajo J.; Mbwambo, Jessie K.; Maman, Suzanne

2012-01-01

380

Genome sequence of a 45,000-year-old modern human from western Siberia.  

PubMed

We present the high-quality genome sequence of a ?45,000-year-old modern human male from Siberia. This individual derives from a population that lived before-or simultaneously with-the separation of the populations in western and eastern Eurasia and carries a similar amount of Neanderthal ancestry as present-day Eurasians. However, the genomic segments of Neanderthal ancestry are substantially longer than those observed in present-day individuals, indicating that Neanderthal gene flow into the ancestors of this individual occurred 7,000-13,000 years before he lived. We estimate an autosomal mutation rate of 0.4 × 10(-9) to 0.6 × 10(-9) per site per year, a Y chromosomal mutation rate of 0.7 × 10(-9) to 0.9 × 10(-9) per site per year based on the additional substitutions that have occurred in present-day non-Africans compared to this genome, and a mitochondrial mutation rate of 1.8 × 10(-8) to 3.2 × 10(-8) per site per year based on the age of the bone. PMID:25341783

Fu, Qiaomei; Li, Heng; Moorjani, Priya; Jay, Flora; Slepchenko, Sergey M; Bondarev, Aleksei A; Johnson, Philip L F; Aximu-Petri, Ayinuer; Prüfer, Kay; de Filippo, Cesare; Meyer, Matthias; Zwyns, Nicolas; Salazar-García, Domingo C; Kuzmin, Yaroslav V; Keates, Susan G; Kosintsev, Pavel A; Razhev, Dmitry I; Richards, Michael P; Peristov, Nikolai V; Lachmann, Michael; Douka, Katerina; Higham, Thomas F G; Slatkin, Montgomery; Hublin, Jean-Jacques; Reich, David; Kelso, Janet; Viola, T Bence; Pääbo, Svante

2014-10-23

381

Fatal accidental hanging from a lanyard key chain in a 10-year-old boy.  

PubMed

Lanyard chains are commonly worn around the neck to hold keys and identification badges. A ten-year-old Black male child was home alone jumping and swinging of the raised crossbars on his mother's four-poster bed. He commonly did this. He also wore a lanyard around his neck with his house key, which he used to let himself in after school. His mother found him hanging on the corner of the bedpost by the lanyard when she returned from work. The death scene showed that he was jumping on the bed and the lanyard hooked over the top of the corner bedpost, causing first and second cervical vertebrae dislocation of an abrupt "drop-type" hanging with neck abrasion marks. Lanyards, or any loose rope material around the neck, are inherently dangerous due to their strength and ability to catch fixed or moving objects. Safety modifications to the lanyards are easily made with "breakaway" Velcro-type or plastic clip fasteners. This is the first reported case of an accidental hanging after review of the medical literature and files of the U.S. Consumer Products Safety Commission. PMID:12455662

Denton, J Scott

2002-11-01

382

Clinical reasoning: a 76-year-old man remaining comatose after cardiopulmonary resuscitation.  

PubMed

A 76-year-old man was admitted to the hospital after having a "cardiac arrest" while riding his bicycle and subsequently falling into a canal. Thirty minutes after the accident, he was resuscitated by an ambulance crew. They detected a ventricular tachycardia, which responded to defibrillation. Thereafter, there was a sinus bradycardia, which was treated with atropine and adrenaline. After 30 minutes of resuscitation, there was return of spontaneous circulation (ROSC). At admission to our hospital, the patient was comatose, with a body temperature of 30°C and Glasgow Coma Scale score (GCS) of E1M1V1. According to protocol for presumed acute hypoxic ischemic encephalopathy, he was started on therapeutic hypothermia. The body temperature of the patient was kept at 32°C to 34°C for 24 hours. A few hours after starting hypothermia, twitches around the eyes and mouth were noticed and a neurology consultation was requested. Neurologic examination during hypothermia and under sedation showed a deeply comatose patient with intact pupillary reaction to light bilaterally and present oculocephalic reflex. He had multifocal random twitching movements involving the face, arms, and legs. These shock-like movements were found to increase by external stimuli. PMID:24491976

Li, Simon C; de Graaf, Marieke T; Cherian, Perumpillichira J

2014-02-01

383

Progressive Multifocal Leukoencephalopathy in a 62-Year-Old Immunocompetent Woman  

PubMed Central

Progressive multifocal encephalopathy (PML) is a rare demyelinating disease that typically presents in immunodeficient patients. We report a case of a previously healthy 62-Year-Old woman who suffered from an unsteady gait, throbbing headaches, and progressive left-sided weakness and numbness. Stroke was initially suspected based on imaging and symptoms. A series of follow-up magnetic resonance images of the brain showed a right parietal lesion growing in size as the patient became unable to walk and experienced increasing lethargy and confusion. A biopsy of the lesion was positive for the John Cunningham virus (JCV). A diagnosis of PML was made and she was started on mefloquine. No improvement was seen on this treatment and her condition worsened. Although PML remains uncommon in immunocompetent individuals, it cannot be ruled out based on their immune status. Although the exact cause remains uncertain, underlying or transient states of immunosuppression may be responsible for reactivation of the JCV in these patients. PMID:24711940

Gourineni, Venkata C.; Kumar, Yogesh; Bordea, Doru; Sena, Kanaga N.

2014-01-01

384

Mediastinal paraganglioma between the great vessels in an 81-year-old woman.  

PubMed

Nonfunctional paragangliomas are slow-growing, typically benign tumors that arise from the extra-adrenal paraganglion of the autonomic nervous system. They are identified and characterized with the use of computed tomography and other imaging methods; for definitive diagnosis, histopathologic evaluation is crucial. Surgical resection is the treatment of choice, and results of postoperative biochemical testing can reveal recurrence. Because of this lesion's familial association, genetic testing is suggested. We report the case of an 81-year-old woman who presented with neck pain, intermittent palpitations, hypertension, and dyspnea. Contrast-enhanced computed tomography of the chest revealed a multilobular, high-density lesion between the aorta and the pulmonary artery in the superior mediastinum. The patient's 24-hour urinary vanillylmandelic acid levels were not elevated, which suggested a nonfunctional tumor. Mediastinal exploration revealed a large, vascular, irregular, consistently firm mass that adhered to the aortic arch. Upon histopathologic analysis after complete resection, the mass was determined to be a paraganglioma with a low index of mitosis. The patient had postoperative respiratory insufficiency that necessitated tracheostomy, but she recovered well after rehabilitation. In addition to reporting our patient's case, we discuss the nature, diagnosis, and treatment of paragangliomas. PMID:23678220

Ghouri, Maaz A; Krishnan, Elangovan; Singh, Awinderpreet; Zaman, Tariq; Hallman, Charles H

2013-01-01

385

Mediastinal Paraganglioma between the Great Vessels in an 81-Year-Old Woman  

PubMed Central

Nonfunctional paragangliomas are slow-growing, typically benign tumors that arise from the extra-adrenal paraganglion of the autonomic nervous system. They are identified and characterized with the use of computed tomography and other imaging methods; for definitive diagnosis, histopathologic evaluation is crucial. Surgical resection is the treatment of choice, and results of postoperative biochemical testing can reveal recurrence. Because of this lesion's familial association, genetic testing is suggested. We report the case of an 81-year-old woman who presented with neck pain, intermittent palpitations, hypertension, and dyspnea. Contrast-enhanced computed tomography of the chest revealed a multilobular, high-density lesion between the aorta and the pulmonary artery in the superior mediastinum. The patient's 24-hour urinary vanillylmandelic acid levels were not elevated, which suggested a nonfunctional tumor. Mediastinal exploration revealed a large, vascular, irregular, consistently firm mass that adhered to the aortic arch. Upon histopathologic analysis after complete resection, the mass was determined to be a paraganglioma with a low index of mitosis. The patient had postoperative respiratory insufficiency that necessitated tracheostomy, but she recovered well after rehabilitation. In addition to reporting our patient's case, we discuss the nature, diagnosis, and treatment of paragangliomas. PMID:23678220

Ghouri, Maaz A.; Krishnan, Elangovan; Singh, Awinderpreet; Zaman, Tariq; Hallman, Charles H.

2013-01-01

386

Effects of a Resistance Training Programme on Isokinetic Peak Torque and Anaerobic Power of 13-16 Years Old Taekwondo Athletes Running Head: Resistance Training and Taekwondo Athletes  

Microsoft Academic Search

The purpose of this study was to determine the effect of a 12 week (2 days per week) resistance training programme at an intensity of 50% of 1RM in adolescent males (13-16 years old) male taekwondo athletes on their isokinetic peak torque and anaerobic power. The intervention group (n=12) aged 14±1 years, participated in the prescribed resistance training programme along

Woo Mei Teng; Chen Chee Keong; Asok Kumar Ghosh; Visvanathan Thimurayan

387

Effectiveness of Saikokaryukotsuboreito (Herbal Medicine) for Antipsychotic-Induced Sexual Dysfunction in Male Patients with Schizophrenia: A Description of Two Cases  

PubMed Central

Antipsychotics sometimes cause sexual dysfunction in people with schizophrenia. The authors report the effectiveness of Saikokaryukotsuboreito (Japanese traditional herbal medicine, Chai-Hu-Jia-Long-Gu-Mu-Li-Tang in Chinese) for antipsychotic-induced sexual dysfunction in two male patients with schizophrenia. The first patient was a 28-year-old man with schizophrenia who suffered erectile dysfunction induced by olanzapine 10?mg/day; the erectile dysfunction significantly improved following the treatment of Saikokaryukotsuboreito 7.5?g/day. The other case was a 43-year-old man with schizophrenia who was receiving fluphenazine decanoate at 50?mg/month and had difficulties in ejaculation; add-on of Saikokaryukotsuboreito 7.5?g/day recovered his ejaculatory function. There has been no report on the effectiveness of Japanese herbal medicine formulations for antipsychotic-induced sexual dysfunction. Although the effectiveness of Saikokaryukotsuboreito needs to be tested in systematic clinical trials, this herbal medicine may be a treatment option to consider for this annoying side effect. PMID:24587934

Takashi, Tsuboi; Uchida, Hiroyuki

2014-01-01

388

Traumatic dental injury among 12-year-old South Brazilian schoolchildren: prevalence, severity, and risk indicators.  

PubMed

An increasing prevalence of traumatic dental injury (TDI) has been reported in the last few decades. The aim of this study was to assess the prevalence and severity of TDI and its association with socio-demographics and physical characteristics in the anterior permanent teeth of 12-year-old Brazilian schoolchildren. A cross-sectional study was carried out in a population-based sample of 1528 subjects attending 33 public and nine private schools (response rate of 83.17%). A single calibrated examiner performed the clinical examinations at the schools and recorded the TDI index (Children's Dental Health Survey criteria), overjet and lip coverage. Height and weight were measured to calculate the body mass index (BMI). Parents/legal guardians answered a questionnaire containing socio-demographic questions. The relationships among TDI, socio-demographic variables and physical characteristics were assessed by survey Poisson regression models. The prevalence of TDI was 34.79% (mild trauma = 24.37%; severe trauma =?10.43%). Male schoolchildren (RR?=?1.41, 95% CI?=?1.23-1.61, P?=?0.002) and schoolchildren from low socioeconomic status (RR?=?1.32, 95% CI?=?1.07-1.64, P?=?0.021) were more likely to present at least one tooth with TDI, whereas students attending 7th grade (advanced students) were less likely to experience TDI (RR?=?0.59, 95% CI?=?0.43-0.82, P?=?0.012). Regarding the severity analysis, students of mid-high (RR?=?1.46, 95% CI?=?1.09-1.94, P?=?0.022), mid-low (RR?=?1.68, 95% CI?=?1.01-2.77, P?=?0.045) and low (RR?=?1.78, 95% CI?=?1.11-2.85, P?=?0.027) socioeconomic status were more likely to have mild trauma when compared with schoolchildren of high socioeconomic status. No significant association between severe trauma and socioeconomic status was observed. In conclusion, this study showed a high prevalence of TDI in 12-year-old Brazilian schoolchildren. Socio-demographic data and school achievement were associated with TDI. PMID:22453035

Damé-Teixeira, Nailê; Alves, Luana Severo; Susin, Cristiano; Maltz, Marisa

2013-02-01

389

[Weight concerns and dieting among 8 to 12-year-old children].  

PubMed

According to a recent study it could be shown that more than one third of female high school students and more than 20 % of male students in the age of 14 to 18 years indicated an impaired eating behaviour, expressed as a medium or high risk to develop eating disorders based upon the standardized Eating Attitudes Test (EAT) . The current study tested the prevalence of weight concerns and dieting as an indicator of problematic eating behaviour among younger children. 230 Thuringian female and male students in the 3 (rd) and 4 (th) year (between 8 and 12-years-old) as well as their parents were investigated using standardized and modified instruments. Weight and height were measured directly to determine the Body Mass Index (BMI) that was put into relation to some factors of potential influence such as parents, peers, media and eating behaviours. It could be shown that 42 % of the boys and 53 % of the girls preferred a thin ideal body image; 32 % of the children revealing normal weight expressed the wish to be thinner. 18 % of the boys and 19 % of the girls tried to lose weight at the time of the investigation. Dieting was influenced by the perceived (not actual) dieting behaviour of the parents. The BMI significantly predicted weight concerns: In total, 85 % of the overweight children but also 17 % of the children with normal weight were convinced to be overweight. The girls' eating behaviour was mostly influenced by the peers, the boys' behaviour by criticism of the parents. Generally, a significant influence of the media could be demonstrated. PMID:15986283

Berger, Uwe; Schilke, Carolin; Strauss, Bernhard

2005-07-01

390

Temperament and character profiles of male COPD patients  

PubMed Central

Background Chronic obstructive pulmonary disease (COPD) is a respiratory disorder, and is characterized by persistent airflow obstruction. These patients are exposed to severe physical limitations and substantial psychosocial trouble. The aims of this study were to determine the temperament and character profiles of personality in patients with COPD and to compare the results with those of healthy controls. Methods Thirty-nine male COPD patients and 67 age- and gender-matched healthy controls completed the self-administered 240-item temperament and character inventory (TCI) and 14-item hospital anxiety and depression scale. The relationships between temperament and character personality profiles and clinical factors such as severity of COPD, anxiety, and depression were evaluated. Results COPD patients had significantly higher mean scores of Harm avoidance and lower mean score of Self-directedness than those of healthy controls. In the COPD patients, the anxiety score was significantly higher (P=0.03) and the depression score was found to be insignificantly higher than that of control group. The TCI profiles were not correlated with the severity of COPD. In COPD patients, Self-directedness and Cooperativeness traits of TCI character negatively correlated with anxiety, but any of traits did not correlate with depression. Conclusions The present study defined the Harm avoidance score was higher and Self-directedness was lower in COPD patients and the COPD severity did not correlate with any of the personality trait. We suggest that during evaluation of COPD patients for treatment, personality trait should also be considered in clinical practice. PMID:23991295

Orhan, Fatma Ozlem; Sucakli, Mustafa Haki; Ozer, Ali; Koksal, Nurhan; Sen, Bilal

2013-01-01

391

Assessing Physicians' Intentions to Talk about Sex when They Vaccinate Nine-Year-Old to 15-Year-Old Girls against HPV  

ERIC Educational Resources Information Center

The human papillomavirus (HPV) vaccine provides physicians with an opportunity to have conversations with girls about sex and sex-related topics. Current research suggests that these conversations are not happening. This study was designed to assess whether physicians would use the HPV vaccination as an opening to communicate with nine-year-old to…

Askelson, Natoshia M.; Campo, Shelly; Smith, Sandi; Lowe, John B.; Dennis, Leslie; Andsager, Julie

2011-01-01

392

Radiographic diagnosis and differentiation of an aggressive angiomyxoma in a male patient  

PubMed Central

Aggressive angiomyxoma is a rare soft-tissue tumor which usually occurs in female patients of reproductive age. Its occurrence in men is even more unusual and as illustrated in this case the difference between pathology suggested by a physical examination and its actual extent can be quite striking. We present a case report of an 81-year-old man with the typical MRI appearances of a pelvic aggressive angiomyxoma, describe imaging and histopathologic features of this rarely seen locally infiltrative neoplasm and also discuss therapeutic options for patients with an aggressive angiomyxoma. PMID:24421942

Karwacki, Grzegorz Marek; Stockli, Martin; Kettelhack, Christoph; Mengiardi, Bernard; Studler, Ueli

2013-01-01

393

[Depression of testosterone secretion in male patients with respiratory failure].  

PubMed

To investigate the changes of testosterone (T) secretion under sustained hypoxia, we determined basal levels of urine T, 17 ketosteroid, luteinizing hormone releasing hormone (LHRH), luteinizing hormone (LH), follicle stimulating hormone (FSH) and response to LHRH and HCG (human chorionic gonadotropin) in male patients with respiratory failure. After evaluating blood gas data, we also measured serum T, LH, FSH, plasma progesterone (P) and 17 hydroxyprogesterone (17OH-P). The subjects were divided into 3 groups according to PaO2; Group 1 with a PaO2 under 60 Torr, Group 2 with a PaO2 between 60 Torr and under 70 Torr, Group 3 was an age-matched control group. Urine T and serum T were significantly lower in Group 1 compared with those of Group 3. In the LHRH test, augmented relative responsiveness and delayed peak value in LH secretion were observed in Group 1, compared with those of Group 3. As for the HCG test, no differences were observed among the 3 groups. The ratio of 17OH-P to P, which indicates activity of 17-hydroxylase, was observed to be diminished with increasing degrees of hypoxia. These data suggest that in male patients with respiratory failure there was depression in T secretion as well as 17-hydroxylase activity due to hypothalamic-pituitary hypofunction. PMID:2615089

Kouchiyama, S; Shinozaki, T; Masuyama, S; Tatsumi, K; Kimura, H; Kuriyama, T

1989-03-01

394

[18-year-old woman with an ovarian tumour detected by coincidence].  

PubMed

Massive ovarian edema (MOE) is a rare, benign disease of young women. Because preoperatively in most cases the differential diagnosis primarily appears to indicate the presence of a malignant tumour, there is a risk that these patients will be subjected to unnecessary overtreatment. In the case of the 18-year-old patient described here, on the basis of the preoperative data the suspected clinical diagnosis was polycystic ovarian (PCO) syndrome. In the MRI the enlarged ovary was interpreted as a mucous tumour. The laparotomy showed a smooth-walled, opalescent ovarian tumour with adnexal torsion. Histopathological examination of the adnexectomy specimen gave the diagnosis of a massive ovarian edema (MOE). Therapeutically, a wedge-shaped excision, immediate-section histology and derotation and suspension of the ovary would have been sufficient. Unnecessary overtreatment can be avoided in young women with enlarged ovaries, if MOE is included in the differential diagnosis and if the characteristic sonography, MRI and macroscopy findings are known. PMID:19585444

Kunz, J; Bannwart, F; Gerber, M; Dombi, V H

2009-07-01

395

Angiosarcoma arising from the tongue of an 11-year-old girl with xeroderma pigmentosum.  

PubMed

Xeroderma pigmentosum (XP) is a rare autosomal recessive defect in DNA endonuclease activity that is associated with the development of cutaneous malignancies, at sun exposed sites, including basal cell carcinoma, squamous cell carcinoma, and melanoma. Squamous cell carcinomas are also known to target the anterior tongue. Patients sometimes develop angiosarcomas, and these invariably arise from sun-exposed skin. A biopsy was taken from a large mass arising in the anterior tongue of an 11-year-old girl with XP and a history of cutaneous basal cell carcinomas. The histopathologic findings demonstrated a high grade epithelioid neoplasm resembling a poorly differentiated squamous cell carcinoma, but the immunohistochemical profile (AE1/AE3 negative, p63 negative, CD31 positive, CD34 positive) established the diagnosis of angiosarcoma. Angiosarcoma is an XP-related tumor that usually arises in sun-exposed skin but can also arise in the oral cavity. For patients with XP who develop epithelioid neoplasms of the oral cavity, epithelioid angiosarcoma should be considered in the differential diagnosis. PMID:21987224

Olson, Matthew T; Puttgen, Katherine B; Westra, William H

2012-06-01

396

Anomalous left main coronary artery causing a myocardial infarction in a 14-year-old boy.  

PubMed

A 14-year-old boy presented with exertional chest pain and was found to have rising cardiac biomarkers. The electrocardiogram revealed ST-segment elevation and T-wave inversion in the anterolateral leads. Coronary arteriograms and coronary computed tomography (CCT) showed an anomalous left main coronary artery originating from the right coronary sinus of Valsalva and coursing intramurally within the wall of the aorta between the aorta and the pulmonary trunk. The proximal left main was narrow with normal distal left main, left anterior descending, and left circumflex coronary arteries. The patient underwent surgical de-roofing of the intramural course of the left main artery with relief of his symptoms. Coronary artery anomalies have been found in 1.3% of the patients in a large arteriographic study. These anomalies are classified on the basis of the origin of the coronary arteries, as well as their course and distribution. Many of these variations are discovered incidentally at arteriography or autopsy. However, some of the anomalies cause symptoms, and a few of them can cause sudden cardiac death, even at a young age. PMID:25073257

Karim, Saima; Young, Thomas; Reilly, John R; Delaney, Patrick

2013-01-01

397

Torsion of the gallbladder in a 3-year-old infant.  

PubMed

A 3-year-old girl was admitted to hospital with complaints of severe upper abdominal pain and vomiting. On admission, a board-like rigidity in the right hypochondrium was noted, along with a high white blood cell count and a high C-reactive protein value. Abdominal ultrasonography (US) revealed a left-sided enlarged gallbladder with a thickened wall, without gallstones. Contrast-enhanced computed tomography (CT) demonstrated an enlarged gallbladder without enhancement effects and a cystic duct located on the right side of the gallbladder. The patient underwent an emergency operation following a diagnosis of torsion of the gallbladder. The gallbladder appeared gangrenous, and 180 degrees clockwise torsion was found at the neck of the gallbladder. The gallbladder was straightened and then removed without difficulty because there was only slight inflammation around Calot's triangle and the gallbladder was not fixed to the liver. Histopathological examination revealed an acute bleeding infarction of the gallbladder. The patient was discharged on the ninth day after surgery, without any complications. The present case suggested that abdominal US and contrast-enhanced CT examinations are helpful in making a correct diagnosis of torsion of the gallbladder even in an infant; in the event of this diagnosis, prompt cholecystectomy is necessary. PMID:19165413

Hamada, Takayuki; Tajima, Yoshitsugu; Yamaguchi, Junzo; Ueda, Takashi; Izawa, Kunihide; Ohtani, Hiroshi; Shimokawa, Isao; Kanematsu, Takashi

2009-01-01

398

Gallbladder torsion-induced emphysematous cholecystitis in a 16-year-old boy.  

PubMed

The patient was a 16-year-old boy who had turned to the right rapidly as he fielded a baseball that had come to him quickly. Two days after this event, which occurred in July 2004, he was admitted to hospital with repeated vomiting and increasing right hypochondralgia. Laboratory examination on admission showed elevation of the white blood count and of serum C-reactive protein and total bilirubin. Computed tomography on admission demonstrated an enlarged gallbladder and a thickened wall without gallstones, and magnetic resonance imaging performed 1 day later showed air within the gallbladder wall. His symptoms worsened, with a positive Murphy's sign, and emergency laparotomy was performed, with a diagnosis of emphysematous cholecystitis. Intraoperatively, the gallbladder was dark red, necrotic, distended, and enlarged. The cystic duct was attached only to the mesentery, and the gallbladder was floating freely, with the neck of the gallbladder having rotated 180 degrees counterclockwise, leading to a definitive diagnosis of gallbladder torsion with emphysematous cholecystitis. Cholecystectomy was performed, and analysis of bile showed Escherichia coli to be the causative organism. Histopathologic examination revealed necrotized cholecystitis. The patient is doing well 25 months after surgery, with an uneventful postoperative course. PMID:18040631

Tanaka, Shogo; Kubota, Daisuke; Oba, Kazuki; Lee, Sang Hun; Yamamoto, Takatsugu; Uenishi, Takahiro; Tanaka, Hiromu; Kubo, Shoji; Matsuyama, Mitsuharu

2007-01-01

399

A 58-Year-Old Woman with Recurrent Hemoptysis after Successful Bronchial Artery Embolization  

PubMed Central

Massive hemoptysis is a life-threatening complication of respiratory disease. It is an emergency requiring immediate medical attention. A 58 year-old woman with bronchiectasis was admitted to the hospital following episodes of massive hemoptysis. Chest CT scan and bronchoscopy did not reveal any endobronchial lesion and bronchial artery angiography and embolization were performed successfully. Despite successful embolization, her hemoptysis recurred and the patient underwent angiography for the 2nd time; which showed normal left bronchial artery and occluded right intercostobronchial artery. Lower thoracic aortogram revealed a systemic non-bronchial artery in the right lower lung field and evidence of pulmonary shunting. Super-selective angiogram of this artery showed vascularity to lower esophagus and considerable supply of the right lower lung field with pulmonary vascular shunting. Embolization of this non-bronchial systemic artery was carried out successfully with complete occlusion. Few days after the embolization, the patient reported pleuritic and epigastric pain and also complained of odynophagia and dysphagia; which were managed conservatively. Four days later, her symptoms improved and she was discharged subsequently. At 40-day follow up, she was still symptom-free with no hemoptysis.

Pourdowlat, Guitti; Kashani, Babak Sharif; Bagheri, Alireza

2014-01-01

400

Sudden onset vision loss in an 8-year-old female with McCune-Albright syndrome.  

PubMed

We describe a case of an 8-year-old girl with large irregular café au lait macules on the right cheek and right lower extremity presenting with sudden onset vision loss and found to have polyostotic fibrous dysplasia on imaging. The classic triad of McCune-Albright syndrome is discussed along with the importance of recognition in patients with partial presentation. This case also highlights a rare and potentially devastating neurologic complication of McCune-Albright syndrome, as well as the need for early diagnosis and continual surveillance in these patients. PMID:23013381

Kim, David; Wysong, Ashley; Lai, Jennifer; Alcorn, Deborah M; Benjamin, Latanya T

2014-01-01

401

Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds  

MedlinePLUS

... 1-Year-Olds May Be at Risk for Obesity Later, Study Finds But experts say genes aren' ... 2014 Related MedlinePlus Pages Genes and Gene Therapy Obesity in Children Toddler Health TUESDAY, Oct. 21, 2014 ( ...

402

Feeding and Caring for a Two-Year-Old 4-H Futurity Horse  

E-print Network

This publication explains how to care for a 2-year-old horse and have a successful 4-H futurity horse project. Topics include proper nutrition; regular coat, hoof, and health care; adequate exercise; and consistent training. Activities are included...

Antilley, Teri J.; Sigler, Dennis

2009-05-15

403

Osteosarcoma in a 6-year-old Newfoundland dog: limb-sparing surgery and cisplatin chemotherapy.  

PubMed

A 6-year-old Newfoundland dog was presented with left forelimb lameness, which was diagnosed as osteosarcoma and treated with an endoprosthetic limb-spare surgery and cisplatin chemotherapy. PMID:18050799

Dawe, Janelle

2007-11-01

404

Physiological and Behavioral Regulation in Two-Year-Old Children with Aggressive\\/Destructive Behavior Problems  

Microsoft Academic Search

A sample of 99 two-year-old children was selected on the basis of parents' responses to two administrations of the Child Behavior Checklist for two- to three-year-olds. Forty-nine of these children displayed symptoms of aggressive\\/destructive (externalizing) problems that were in the borderline clinical range (labelled “high risk”) and 50 children displayed few such symptoms (“low risk”). The children were assessed in

Susan D. Calkins; Susan E. Dedmon

2000-01-01

405

Is peer victimization related to body esteem in 10-year-old girls and boys?  

Microsoft Academic Search

Several studies show that a history of exposure to appearance-related teasing is linked to body dissatisfaction. This study extends those findings by examining the impact of bullying, and other forms of peer victimization, on different aspects of 10-year-old girls’ and boys’ body esteem. Participants were 960 Swedish 10-year-olds, 515 girls and 445 boys. Principal results show that social exclusion is

Carolina Lunde; Ann Frisén; Carl Philip Hwang

2006-01-01

406

Drug Ingestions in Children 10-14 Years Old: An Old Problem Revisited  

ERIC Educational Resources Information Center

To determine changes in rates of drug ingestions in 10-14 year old children in our country, a retrospective chart review of 10-14 year olds hospitalized for drug ingestion between 1993-1995 and 2000-2004 was performed. Odds ratios and Chi-square were used for analyses. From 1993-1995 there were 92.8 ingestions/100,000 children/year; from 2000-2004…

Pomerantz, Wendy; Gittelman, Michael; Farris, Sarah; Frey, Lauren

2009-01-01

407

Muscular strength and aerobic capacity in men 50–64 years old  

Microsoft Academic Search

Summary  44 men 50–54 years old, 22 men 55–59 and 5 men 60–64 years old were examined with regard to maximal isometric strength of the elbow flexors and lifting strength.The mean value of the muscular strength of the elbow flexors was for the first age group 25 kp, for the second 26 and for the third 21 kp. The corresponding values

Irma Ästband; Rune Hedman

1963-01-01

408

Soda Consumption and Overweight Status of 2YearOld Mexican-American Children in California  

Microsoft Academic Search

Objective: The prevalence of overweight in United States children, 2 to 5 years old, has increased 2-fold since 1975, with the highest prevalence in Mexican Americans. The objective of this study was to determine the association between current soda consumption and overweight in 2-year-old Mexican-American children.Research Methods and Procedures: The Center for the Health Assessment of Mothers and Children of

Marcella L. Warner; Kim Harley; Asa Bradman; Gloria Vargas; Brenda Eskenazi

2006-01-01

409

Prevalence and Severity of Dental Caries in 12YearOld Children in Kaunas, Lithuania 1995  

Microsoft Academic Search

In order to evaluate suitable strategies for control of dental caries, a longitudinal study of caries progression has been initiated among 12-year-old children in Kaunas, Lithuania. The aim of the present paper was to describe the baseline caries situation in a sample of 12-year-olds, who had been examined using caries diagnostic criteria which differentiate between active and inactive caries lesions

V. Machiulskiene; B. Nyvad; V. Baelum

1998-01-01

410

Self-Esteem Links in Families with 12YearOld Children and in Separated Spouses  

Microsoft Academic Search

The aim of the present study is to map associations of self-esteem in families with 12-year-old children and in separated spouses. The authors assessed self-esteem using the Harter Self-Perception Profile for Adults (B. Messer & S. Harter, 1986) and the Harter Self-Perception Profile for Children (S. Harter, 1988; L. Wichstrom, 1995) in (a) 1,236 pairs of spouses and their 12-year-old

Kristina Elfhag; Per Tynelius; Finn Rasmussen

2010-01-01

411

The Social Development of Two Year Old Children in Residential Nurseries.  

ERIC Educational Resources Information Center

This study focuses upon some aspects of the social behavior of 2-year-old children being reared in long-stay residential nurseries. These children are compared with working class 2-year-old children being raised in two-parent homes in which the mother is not working full-time and there are no older siblings of preschool age. All children were…

Tizard, Jack; Tizard, Barbara

412

An Objective Method for Measurement of Sedentary Behavior in 3- to 4Year Olds  

Microsoft Academic Search

Objective: To test the ability of accelerometry to quantify sedentary behavior in 3- to 4-year-old children.Research Methods and Procedures: We developed a cut-off for accelerometry output (validation study) in 30 healthy 3 to 4 year olds, which provided highest sensitivity and specificity for the detection of sedentary behavior relative to a criterion method of measurement, direct observation using the children’s

John J. Reilly; Jennifer Coyle; Louise Kelly; Genevieve Burke; James Y. Paton

2003-01-01

413

Polymorphisms of glutathione S-transferase M1 and male infertility in Taiwanese patients with varicocele  

Microsoft Academic Search

BACKGROUND: To examine glutathione S-transferase M1 (GST M1) gene polymorphism and male infertility in Taiwanese patients with varicocele, 80 young male patients with varicocele (group 1), 62 young male patients with subclinical varicocele (group 2) and 60 normal young males (group 3) were recruited in this study. METHODS: GST M1 null homozygous genotype (GST M1 (-)) and the occurrence of

Shiou-Sheng Chen; Luke S. Chang; Haw-Wen Chen; Yau-Huei Wei

414

Cardiomyopathy in a male patient with neutropenia and growth delay  

PubMed Central

Neutropenia encompasses a family of neutropenic disorders, both permanent and intermittent, ranging from severe (<500 neutrophils/mm3) to mild (500–1500 neutrophils/mm3), which may also affect other organ systems such as the pancreas, central nervous system, heart, muscle and skin. Neutropenia can lead to life-threatening pyogenic infections whose severity is roughly inversely proportional to the circulating neutrophil counts. When neutropenia is detected, an attempt should be made to establish the etiology, and to distinguish acquired forms (the most frequent, including post viral neutropenia and autoimmune neutropenia) and congenital forms (rare disorders) that may be either isolated or part of a complex rare genetic disease. We report on a male patient initially diagnosed with isolated neutropenia who later turned out to be affected with Barth syndrome, a rare complex inherited disorder. PMID:24887148

2014-01-01

415

Central precocious puberty in a 3 year-old girl with Phenylketonuria: a rare association?  

PubMed Central

Background Central precocious puberty (CPP) and phenylketonuria (PKU) are two rare conditions, the latter being the rarer. To date, only one case featuring both these conditions has been reported, and hyperphenylalaninemia was assumed triggering CPP. Case presentation We present a 3.2?years old girl referred with a 12?months history of breast and pubic hair development, and vaginal discharge. Hyperphenylalaninemia had been identified by newborn screening and PKU subsequently confirmed by plasma amino acid and genetic analysis. Early dietary control of plasma phenylalanine had been excellent afterwards, resulting in phenylalanine concentrations consistently within the recommended range. Clinical scenario, hormonal assessment and imaging were in keeping with true idiopathic central precocious puberty. Treatment with long lasting gonadotropin-releasing hormone analogue led to regression of secondary sexual characteristics. Conclusion We describe for the first time CPP in a girl affected with PKU but with persistently well controlled blood phenylalanine concentrations. This finding is in contrast to a previous report which suggested persistently high phenylalaninemia levels as potential trigger for CPP in PKU patients. Our report, together with the lack of evidence in published cohort studies of children with PKU, strongly suggests this rare association is coincidental and independent of the presence of severe hyperphenylalaninemia. PMID:24773629

2014-01-01

416

May-Thurner Syndrome in a 68-Year-Old Woman after Remote Abdominal Surgery  

PubMed Central

May-Thurner syndrome, also called iliac vein compression syndrome, is a rare cause of left iliac deep vein thrombosis, which arises from pulsatile compression of the left common iliac vein by the right common iliac artery. The resultant endothelial damage and intraluminal spur formation can lead to iliac deep vein thrombosis and sudden-onset left-lower-extremity edema and pain. Patients typically present with May-Thurner syndrome in their 2nd to 4th decades of life. In chronic form, the syndrome can be debilitating because of venous claudication and stasis ulcers. Surgical approaches and endovascular interventions have been effective in the acute phase of the disease, and intravenous stents can resolve the manifestations of chronic venous compression. Anticoagulation alone is ineffective, and a consensus regarding the usage and duration of antiplatelet and antithrombotic therapy has not been established. We present the case of a 68-year-old woman with a remote history of abdominal surgery who presented with left-lower-extremity edema and pain. Magnetic resonance venography of the pelvic veins yielded a definitive diagnosis of May-Thurner syndrome. Catheter-directed thrombolysis and intravenous stent placement resolved her symptoms, and she was discharged from the hospital on anticoagulative therapy. A year later, she had no residual pain or edema, and the affected veins were patent with normal phasic flow and normal responses to compression and augmentation. PMID:23467335

Fernando, Rajeev Ruben; Koranne, Ketan Prakash; Schneider, Daniel; Fuentes, Francisco

2013-01-01

417

[A 52 year-old woman with fever, cough and dyspnoea].  

PubMed

A 52 year-old woman with gastric cancer treated with surgery and chemotherapy, is admitted in our Internal Medicine Department because of the presence of fever (max 41.2 degrees C), dyspnoea, non-productive cough and mental confusion. The anamnesis and the physical examination address to the diagnosis of CAP (Community-Acquired Pneumonia); in particular the alteration of consciousness and the onset of symptoms after the insertion of a nose-gastric tube let us to consider the diagnosis of aspiration pneumonia. The clinical presentation and radiological imaging (Rx and CT of thorax) suggest the pattern of bronchiolitis obliterans with organizing pneumonia (BOOP). BOOP is not a disease, but a non specific pattern of answer to a lung injury. It can be either idiopathic or associated with a variety of causes, such as infections, drugs, radiations and connective tissue diseases. Besides the clinical course is complicated by the onset of an ARDS (Adult Respiratory Distress Syndrome). The gold standard for the diagnosis is represented by lung biopsy with hystopathologic confirmation but, if it cannot be done, it's necessary to start immediately steroid therapy because BOOP may be fatal. The patient received antibiotic and steroid therapy with success. PMID:15700634

Palma Modoni, A; De Galasso, L; Scriccia, S; Milanetti, F; Sgambato, E; Spoto, S; Costantino, S

2004-09-01

418

Central Precocious Puberty and Granulosa Cell Ovarian Tumor in An 8-Year Old Female  

PubMed Central

Ovarian tumors associated with hormonal changes of the peripheral iso-sexual precocious puberty are of common presentation. We describe here a rare case of juvenile granulosa cell tumor in a female with central precocious puberty (CPP). An 8-year old girl with CPP presented with vaginal bleeding four months after the diagnosis and before starting treatment with gonadotropin-releasing hormone (GnRH)-analogs. Suppression of basal follicle-stimulating hormone (FSH) level, elevation of serum estradiol, progesterone and Cancer Antigen-125 were documented. Abdominal ultrasound examination (US) and magnetic resonance imaging showed a pelvic mass affecting the left ovary. A left salpingo-oophorectomy was performed and the mass was totally resected. Juvenile granulosa cell ovarian tumor was diagnosed. One month post surgery, estradiol and progesterone decreased to values of the first evaluation and FSH increased; Cancer Antigen-125 resulted normal while ultrasound pelvic examination showed absence of pelvic masses. In our patient, the tumor had grown very quickly since hormonal data demonstrated a CPP without any evidence of ovarian mass on US only four months before diagnosis. The overstimulation of the FSH or aberrant activation of FSH receptors may have contributed to the development of the mass. PMID:24198925

Calcaterra, Valeria; Nakib, Ghassan; Pelizzo, Gloria; Rundo, Barbara; Anna Rispoli, Gaetana; Boghen, Stella; Bonetti, Federico; Del Monte, Barbara; Gertosio, Chiara; Larizza, Daniela

2013-01-01

419

Weight loss strategies for adolescents: a 14-year-old struggling to lose weight.  

PubMed

With prevalence approaching 20% in the United States, adolescent obesity has become a common problem for patients, parents, and clinicians. Obese adolescents may experience physical and psychosocial complications, as illustrated by the case of Ms K, a 14-year-old girl with a body mass index of 40. Unfortunately, the effectiveness of pediatric obesity treatment is modest in younger children and declines in older children and adolescents, and few interventions involving adolescents have produced significant long-term weight loss. Nevertheless, novel strategies to alter energy balance have shown preliminary evidence of benefit in clinical trials, including a diet focused on food quality rather than fat restriction and a lifestyle approach to encourage enjoyable physical activity throughout the day rather than intermittent exercise. Parents can have an important influence on weight-related behaviors in adolescents despite typically complicated emotional dynamics at this age, especially through the use of noncoercive methods. A key parenting practice applicable to children of all ages is to create a protective environment in the home, substituting nutritious foods for unhealthful ones and facilitating physical activities instead of sedentary pursuits. Other behaviors that may promote successful long-term weight management include good sleep hygiene, stress reduction, and mindfulness. Ultimately, the obesity epidemic can be attributed to changes in the social environment that hinder healthful lifestyle habits, and prevention will require a comprehensive public health strategy. PMID:22215761

Ludwig, David S

2012-02-01

420

A 63 year old woman with white matter lesions and pachymeningeal inflammation.  

PubMed

We describe the case of a 63-year-old woman with CNS Rosai-Dorfman disease, presenting with diffuse dural infiltration, mimicking idiopathic hypertrophic pachymeningitis, and right vertebral artery dissection. Her symptoms included a progressive 11-month history of vertigo, gait ataxia, and right thalamic stroke. A diagnosis of CNS Rosai-Dorfman disease was made following open dural biopsy, and later confirmed on autopsy studies. The autopsy demonstrated widespread dural infiltration by inflammatory cells, principally large histiocytes, many of which exhibited emperipolesis, a characteristic finding in Rosai-Dorfman disease. A second pathological finding on autopsy was the presence of multiple demyelinating plaques (with preservation of axons), located in the corpus callosum, periventricular white matter, and multiple brainstem segments. These were consistent with a diagnosis of multiple sclerosis. This case description serves to remind clinicians that CNS Rosai-Dorfman disease—although uncommon—may present as a focal, dural-based, hemispheric mass lesion, or as diffuse pachymeningeal inflammation. Our case was also unusual due to the co-existence of CNS Rosai-Dorfman disease, multiple sclerosis, and polycythemia vera (all rare diseases) in a single patient. Although the overlap of disorders may have been co-incidental, one could raise the question whether all three disorders were triggered by the same underlying dysimmune state. PMID:23432650

Breiner, Ari; Dubinski, William; Gray, Bruce; Munoz, David G

2013-03-01

421

Early-onset of multiple sclerosis in a 5-year-old girl.  

PubMed

Childhood multiple sclerosis is a rare demyelinating autoimmune disease with particular features. Onset of multiple sclerosis is extremely uncommon in early childhood, particularly before 6 years of age. We report the case of a 5-year-old girl admitted to the hospital for altered consciousness and rapid onset of right hemiparaplegia. Magnetic resonance imaging (MRI) of the brain showed multifocal white matter disease with T2 hyperintense oval lesions in subcortical, periventricular, and cerebellar hemispheres. Treatment with high dose intravenous methylprednisolone (30 mg/kg/day for 3 days) improved symptoms. Intravenous corticosteroid therapy was followed by 1mg/kg/day of oral prednisone. A second MRI, 40 days later, revealed new disseminated T2 hyperintense lesions in the frontal periventricular white matter, corpus callosum, left middle cerebellar peduncle, and dorsal spinal cord, leading to the diagnosis of multiple sclerosis. Azathioprine (2.5 mg/kg/day) was started and the steroid dose was tapered before being stopped after 3 months. After 2 years of follow-up, the patient has remained asymptomatic with a normal neurological exam and with no relapse or side effects of azathioprine. This work shows the particularities in clinical and radiological features of multiple sclerosis in a child aged less than 6 years. PMID:24462295

Gargouri, L; Safi, F; Fourati, H; Kmiha, S; Turki, F; Zidi, F; Mnif, Z; Mahfoudh, A

2014-03-01

422

Cortisol Reactivity in Two-Year-Old Children Prenatally Exposed to Methamphetamine  

PubMed Central

Objective: Until now, the functioning of the hypothalamic–pituitary–adrenal (HPA) axis in children with prenatal methamphetamine exposure (PME) had been unexamined. Previous research indicates that prenatal exposure to stimulant drugs is associated with dose-response alterations in neural growth and connectivity and consequent neurobehavioral deficits. In addition, children of drug-using parents are at an increased risk for exposure to chronic postnatal stress. In this preliminary study, we examined the associations of PME and postnatal environmental stress with cortisol stress reactivity in children with PME. Method: Participants were 2-year-old children (N = 123; 55.3% male) with PME from a multicenter longitudinal Infant, Development, Environment, and Lifestyle Study. Saliva samples were obtained before and after a stress-inducing separation task. Hierarchical multiple regression analyses examined prenatal drug exposure, methodological and postnatal stress covariates, and interactions between levels of PME and postnatal stress. Results: Mild to moderate potential for child physical abuse moderated increased cortisol reactivity in high exposed children with PME. Blunted cortisol reactivity was associated with caregiver’s postnatal alcohol use, child’s behavioral dysregulation, and the interaction between higher levels of PME and caregiver’s psychopathology. Conclusions: Consistent with the known effects of stimulant drugs and chronically stressful environments on the HPA axis and, thus, the toxic stress and allostatic load phenomena, our results imply that elevated PME may be associated with alterations in the programming of the HPA axis reflecting hyperactivity, which under significant and chronic environmental stress then may become hypoactive. PMID:23490574

Kirlic, Namik; Newman, Elana; LaGasse, Linda L.; Derauf, Chris; Shah, Rizwan; Smith, Lynne M.; Arria, Amelia M.; Huestis, Marilyn A.; Haning, William; Strauss, Arthur; Dellagrotta, Sheri; Dansereau, Lynne M.; Abar, Beau; Neal, Charles R.; Lester, Barry M.

2013-01-01

423

Health-related behaviours and psycho-social characteristics of 18 year-old Australians.  

PubMed

Psychosocial variables associated with health-related behaviours for diet, physical activity, alcohol consumption and smoking were examined in 18 year-old Australian men (n = 301) and women (n = 282). These psychosocial variables included Type A behaviour and depression, perceived self-efficacy for engaging in healthy behaviours and perceived barriers to performing these behaviours. Self-efficacy for following a healthy diet and moderating alcohol intake was greater in females but males had higher self-efficacy for physical activity. Self-efficacy for smoking did not differ according to gender. Lack of willpower was perceived as a barrier to desirable dietary, smoking and physical activity behaviours. Other perceived diet-related barriers included buying suitable foods when eating out, ignorance about appropriate foods and, in young women, perceived expense. Barriers for desirable levels of physical activity included planning time, tiredness, limiting social life and lack of social support. Social occasions were the main perceived barriers preventing both alcohol moderation and quitting smoking. Lack of family support, stress and concerns about weight gain, particularly in women, were perceived barriers to smoking cessation. Type A behaviour was associated with smoking and "unsafe" drinking in both men and women, generally unhealthy dietary choices in young women but with greater physical activity in young men. Depressive affect was significantly higher in female smokers and "unsafe" drinkers and tended to have an inverse relationship with physical activity in men and women. Depressive affect was inversely related to self-efficacy in both men and women for each of the health behaviours examined. Health promotion in young adults should therefore attempt to increase self-efficacy and address perceived barriers to change, taking into account gender-related differences in attitudes and the influence of depression and Type A characteristics on health-related behaviours. PMID:9351145

Milligan, R A; Burke, V; Beilin, L J; Richards, J; Dunbar, D; Spencer, M; Balde, E; Gracey, M P

1997-11-01

424

Dermafrac™: an innovative new treatment for periorbital melanosis in a dark-skinned male patient.  

PubMed

Periorbital melanosis (under eye dark circles) is an often idiopathic cosmetically disturbing condition that is poorly responsive to currently available treatment modalities. We present the case of a 48-year-old man (skin phototype V) with significant idiopathic periorbital melanosis and who had good to excellent reduction in periorbital melanosis with the new DermaFrac™, which combines microneedling with simultaneous infusion of a serum containing active ingredients. The possible mechanisms of benefit are discussed. DermaFrac™ may be an innovative and effective new treatment option for patients with periorbital melanosis. PMID:24163534

Sahni, Kanika; Kassir, Martin

2013-07-01

425

Dermafrac™: An Innovative New Treatment for Periorbital Melanosis in a Dark-Skinned Male Patient  

PubMed Central

Periorbital melanosis (under eye dark circles) is an often idiopathic cosmetically disturbing condition that is poorly responsive to currently available treatment modalities. We present the case of a 48-year-old man (skin phototype V) with significant idiopathic periorbital melanosis and who had good to excellent reduction in periorbital melanosis with the new DermaFrac™, which combines microneedling with simultaneous infusion of a serum containing active ingredients. The possible mechanisms of benefit are discussed. DermaFrac™ may be an innovative and effective new treatment option for patients with periorbital melanosis. PMID:24163534

Sahni, Kanika; Kassir, Martin

2013-01-01

426

Synchronous primary neoplasms of the bladder, skin and breast in a male patient: a case report  

PubMed Central

The incidence of multiple primary malignant neoplasms increases with age, reflecting an increase in overall cancer risk in older patients. Cases of two or more concurrent primary cancers are still rare, although its incidence is increasing. Here, we report the case of a 57-year-old man who was referred to our institution with synchronous squamous cell carcinoma of the skin on the forehead, infiltrating ductal carcinoma of the breast, and transitional cell carcinoma of the urinary bladder. To the best of our knowledge, this is the first reported case in literature of this combination of primary neoplasms. PMID:24139546

2013-01-01

427

Vogt-Koyanagi-Harada disease in an 8-year-old boy  

PubMed Central

Vogt-Koyanagi-Harada (VKH) disease is an autoimmune disease involving pigmented tissue in eyes, auditory system, skin, and central nervous system. The pathogenesis is a result of T cell lymphocyte reaction against melanocyte component, tyrosinase and tyrosinase-related protein. This disease uniquely affected pigmented race in Asia and native America, mostly women aged 20-50. We reported an 8-years-old boy complained for visual disturbance since 6 weeks prior admission. Two years earlier, the parents noted the patient eyes were looked red when photographed (suggesting a dilated pupil) preceded by whitened on the right forehead and nose and whitened hair, eyebrow and eyelashes. The examination showed a vitiligo and skin atrophy on right frontal and right nasal, poliosis on the eyebrows, eyelids and hair. The diameter of right pupil was 8 mm, with a paresis on 3rd, 4th, 6th, and 9th nerves. Fundus examination revealed sunset glow appearance. The visual acuity on the right eye: 2/60, left eye: 1-0. There's positive serology for antitoxoplasma IgG, anti Rubella IgG, anti CMV IgG. The patient was diagnosed with a VKH disease and then prescribed with methylprednisolone 1 mg/kg/day. The patient also had further follow up with dermatovenerologist and ophthalmologist. The eye examination revealed an improvement on right eye panuveitis, with a remaining keratic precipitate in the endothelium, and minimal flare and cell on the anterior chamber. ENT consultation revealed no ear inflammation or hearing disturbance. PMID:22053304

Karfiati, Feti; Ghrahani, Reni; Sapartini, Gartika; Sahril, Indra

2011-01-01

428

Chondroblastoma of the Medial Cuneiform Bone in a 32-Year-Old Woman  

PubMed Central

Patient: Female, 32 Final Diagnosis: Chondroblastoma Symptoms: Pain Medication: — Clinical Procedure: — Specialty: Oncology Objective: Unusual clinical course Background: 1% of all bone tumors are Chondroblastomas. Chondroblastomas, initially considered to be an osteoclastoma variant are benign, cartilaginous tumors which usually occur in the epiphysis of long bones, especially in the humerus, tibia, and femur, most common in children and young adults between the ages of 10 and 20 years. 4% of all chondroblastomas settle in the talus whereas cuneiform and other tarsal bones are very rare sites for the development of this benign chondroid lesion. Case Report: A case of chondroblastoma involving the medial cuneiform of the left foot of a 32-year-old woman is described. The patient presented with moderate localized pain and tenderness over the medial aspect of her left foot. Radiographs showed a lytic expansile lesion within the right cuneiform bone indicating a bone tumor. Biopsy demonstrated cellular areas made up of round, polygonal cells, with round-oval nucleus and chondroblasts that appear with a thin calcification rim. Intralesional curettage and synthetic bone grafting with PRP (Platelet-Rich Plasma) application was performed for its treatment. After 18 month follow up, osteointegration was observed with the defect completely filled and the patient was free of disease and pain. Conclusions: A painful, expansile, thin, sclerotic lesion detected at the cuneiform should arise suspicion for chondroblastoma even at age over 20 years. Meticulous curettage of the lesion from a small window with removal of the lesion followed by injectable phosphocalcic cement application with autologous PRP can be considered as a curative and technically simple treatment method. PMID:25072961

Ar?kan, Murat; Aktas, Erdem; To?ral, Guray; Y?ld?r?m, Ahmet; Kandemir, Olcay

2014-01-01

429

[A case of pituitary metastasis in a patient with male breast cancer developing anterior lobe dysfunction successfully treated by using hormone replacement therapy].  

PubMed

Male breast cancer is a rare disease and accounts for <1% of all breast cancers. Anterior lobe dysfunction of the pituitary gland is known to occur in only 15% of patients with pituitary gland metastasis, and diabetes insipidus occurs in 70% of patients in this subset. We report a case of pituitary metastasis in a patient with male breast cancer that resulted in anterior lobe dysfunction. A 64-year-old man presented with consciousness loss and gait disturbance. His serum sodium level was 117mEq/L. Magnetic resonance imaging revealed a suprasellar tumor that showed inhomogeneous enhancement and was attached to the optic chiasm. Diabetes insipidus was not evident at admission, but was observed immediately after the administration of the steroid hormone complement. The patient underwent subtotal resection of the tumor via a transsphenoidal approach. Pathological examination revealed metastasis from estrogen receptor-positive breast cancer. The patient underwent conventional post-operative radiotherapy combined with hormone replacement therapy and has remained free of symptoms for 16 months. Herein, we discuss the neuroendocrinology of and treatment for pituitary gland metastasis. PMID:25006103

Fukunaga, Atsushi; Yazaki, Takahito; Shimizu, Katsuyoshi; Ochiai, Masato

2014-07-01

430

The primary percutaneous coronary intervention for acute anterior myocardial infarction in a middle-aged male patient with bilateral coronary artery to pulmonary artery fistulas.  

PubMed

A 38-year-old man admitted to emergency department with 2 h of typical substernal chest pain, shortness of breath and nausea. The ECG revealed sinus rhythm with a 3 mm ST elevation in precordial leads V1-V6. The coronary angiography revealed acute total occlusion in left anterior descending artery (LAD) with normal circumflex and right coronary artery (RCA) along with bilateral fistulas arising from the proximal LAD and ostial RCA draining into the main pulmonary artery. Therefore, primary percutaneous coronary intervention and bare metal stent implantation was performed to culprit LAD lesion. The electrocardiographically gated 64-slice multidetector-row CT showed two large, tortuous abnormal vessels which arose from the both ostial part of the RCA and LAD draining into the main pulmonary artery. We report an unusual case of bilateral coronary artery to pulmonary artery fistulas leading to acute anterior myocardial infarction in a middle-aged male patient. PMID:23152179

Altay, Servet; Cakmak, Huseyin Altug; Velibey, Yalcin; Erer, Betul

2012-01-01

431

Recurrent ascites with severe hypoproteinemia in 4-year-old child: A diagnostic dilemma - An atypical presentation of hypothyroidism  

PubMed Central

Hypothyroidism is frequently encountered condition to a pediatrician. Passive effusions into serous cavities, sometimes to considerable amount are frequently noted. However, the significant ascites caused by this is rare in a child and in no instance, it is too excessive. So diagnosis is frequently delayed and patient frequently receive unnecessary procedures such as liver, even gastrointestinal biopsies. Analysis of ascitic fluid shows exudative nature with high protein. The case we present here is a 4-year-old female child with recurrent ascites, developmental delay and hypoproteinemia. High index of suspicion can lead to diagnosis. Over all prognosis is excellent after stating replacement therapy with L-thyroxine. PMID:25143889

Mehta, Sudhir; Sanghvi, Jyoti; Kela, Gunjan

2014-01-01

432

Pulmonary medium vessel vasculitis in an 11 year old boy: Hughes Stovin syndrome as a variant of polyarteritis nodosa?  

PubMed Central

We present the case of an 11-year-old boy presenting with haemoptysis, dyspnoea and weight loss as a manifestation of isolated pulmonary vasculitis, leading to pulmonary hypertension. He also appeared to have a longstanding dural venous sinus thrombosis. This rare presentation, especially in childhood, might represent a case of the seldomly reported Hughes-Stovin syndrome. The patient achieved remission after therapy with cyclophosphamide pulses and high-dose steroids. Based on the presented case and review of the literature, we propose that this syndrome might be a variant of polyarteritis nodosa. This report highlights diagnostic issues and describes a successful treatment regimen. PMID:21816089

2011-01-01

433

[Dyspnea on exertion, angina pectoris and loud thrill in the right groin in an 82-year-old man].  

PubMed

We report on the case of an 82-year-old man who was suffering from chest pain and dyspnea. Acute cardiac ischemia could be excluded. Cardiac catheterization also revealed an aneurysm of the right common iliac artery. In addition, an arteriovenous fistula between the iliac artery and vein was detected by computer tomography angiography. Apparently, these symptoms were caused by a high output heart failure with known coronary heart disease. The patient was treated by implantation of prosthesis and oversewing the fistula which led to full recovery. PMID:25070612

Reinhold, C; Lange, T; Haake, H; Weis-Müller, B T

2014-11-01

434

Primary Care Physicians' Knowledge of and Confidence in Their Referrals for Special Education Services in 3- to 5-Year-Old Children  

PubMed Central

Background Children 3 to 5 years old with developmental delays are eligible for special education services. Objective To assess primary care physicians' (PCPs) knowledge, attitudes, and practices regarding their referrals to the special education system on behalf of children 3 to 5 years old. Design/Methods Mail survey of 400 office-based general pediatricians and 414 family physicians in Michigan, fielded in fall 2012 and winter 2013, with a response rate of 44%. The 4-page survey included knowledge questions about special education eligibility, PCPs' role in accessing school-based services, and self-confidence in ability to help patients access these services. Results PCPs neither fully understood requirements for special education services nor were they very confident in identifying 3- to 5-year-old children eligible for special education services. Conclusions PCPs recognize interacting with special education as a relative weakness, and they may be accepting of interventions to improve their knowledge and skills. PMID:24057570

Hastings, Elizabeth A.; Lumeng, Julie C.; Clark, Sarah J.

2014-01-01

435

Effects of perceptual variables on numerosity comparison in 5-6-year-olds and adults  

PubMed Central

Although a critical issue in the debate over the existence of abstract numerical representation, it remains unclear whether and how perceptual variables affect numerosity judgment and how they change across development stages. In this research, we examine the effects of perceptual variables on approximate numerosity comparison in 5–6-year-olds and adults using the identical experimental procedure. In the assessment of the effect of the perceptual variables, we measured precision (i.e., Weber fraction) and accuracy (i.e., point of subjective equality; PSE) of the numerosity comparison. In Study 1, we tested how the manipulation of the cumulative element area would affect approximate numerosity comparison. The results showed that Weber fractions increased and the size of bias enlarged in the large element condition in both adults and 5–6-year-olds. In study 2, we tested how the manipulation of the array area would affect the precision and accuracy of approximate numerosity comparison. The results demonstrated that Weber fractions increased and the size of bias enlarged in the large array condition in both adults and 5–6-year-olds. Overall, our results suggest that the effect of perceptual variables on 5–6-year-olds is qualitatively similar to that on adults. In addition, we also tested whether the performance of approximate comparison correlated with the initial numerical skill in 5–6-year-olds to reveal least relationship between them. PMID:23898308

Tokita, Midori; Ishiguchi, Akira

2013-01-01

436

Seasonal Incidence of Medically Attended Respiratory Syncytial Virus Infection in a Community Cohort of Adults >=50 Years Old  

PubMed Central

Background Diagnostic testing for respiratory syncytial virus (RSV) is not routinely performed in adults. We estimated medically attended RSV seasonal incidence in a community cohort of adults ?50 years old during four influenza seasons (2006–07 through 2009–10). Methods Patients seeking care for acute respiratory illness (ARI) were prospectively enrolled and tested for RSV by multiplex RT-PCR. Results from enrolled patients were used to estimate projected cases among non-enrolled patients with ARI. The seasonal incidence of medically attended RSV was the sum of actual and projected cases divided by the community cohort denominator. Since each enrollment period did not include the entire RSV season, incidence estimates were adjusted to account for the statewide proportion of RSV occurring outside the study enrollment period. Results There were 16,088 to 17,694 adults in the cohort each season and 164 RSV cases in all 4 seasons. The overall seasonal incidence of medically attended RSV was 154 episodes (95% CI, 132–180) per 10,000 persons; the incidence was highest in 2007–08 (179) and lowest in 2006–07 (110). Among persons 50–59, 60–69, and ?70 years old, RSV incidence was 124 (95% CI, 99–156), 147 (95% CI, 110–196), and 199 (95% CI, 153–258), respectively. Conclusions The incidence of medically attended RSV increased with age and was similar during four seasons. PMID:25025344

McClure, David L.; Kieke, Burney A.; Sundaram, Maria E.; Simpson, Melissa D.; Meece, Jennifer K.; Sifakis, Frangiscos; Gasser, Robert A.; Belongia, Edward A.

2014-01-01

437

Primary Cytomegalovirus-Related Eosinophilic Pneumonia in a Three-year-old Child with Acute Lymphoblastic Leukaemia  

PubMed Central

A diagnosis of eosinophilic pneumonia (EP) is rare in patients with acute lymphoblastic leukaemia (ALL). We report a case of EP in association with a primary cytomegalovirus (CMV) infection in a three-year-old Omani child with ALL. The patient presented with fever while undergoing maintenance chemotherapy. He was admitted to the Child Health Department of Royal Hospital, in Muscat, Oman, in November 2011. He was initially thought to have sepsis but failed to respond to antibiotics. Chest computed tomography showed diffuse ground glass lung opacification. Bronchoalveolar lavage (BAL) cytology was consistent with the diagnosis of EP. Polymerase chain reaction tests for CMV were performed on the BAL and blood samples and were both markedly elevated. The patient made a full recovery after treatment with prednisolone and ganciclovir. The association between CMV infection and EP as well as the management of this combination in immunocompromised patients has never been reported in the English literature.

Reesi, Mohammed Al; Al-Maani, Amal; Paul, George; Al-Arimi, Sumaiah

2014-01-01

438

Auditory function in 70- and 75-year-olds of four age cohorts. A cross-sectional and time-lag study of presbyacusis.  

PubMed

Within the framework of the gerontological and geriatric population studies in Göteborg, Sweden, 473 elderly persons were examined using pure-tone audiometry in two recent cohorts. The aim of this study was to present cross-sectionally acquired hearing data in these contemporary groups aged 70 and 75. Another objective was to compare hearing function at the same age over the last two decades (time-lag study) in three 70-year-old cohorts and three 75-year-old cohorts. The largest time-lags were 14 years (75-year-olds) and 21 years (70-year-olds). The most recently tested cohort of 70-year-olds, studied in 1992, demonstrated median pure-tone averages (PTA: 0.5, 1 and 2 kHz) of 20.2 dB HL in the left ear of men and 18.2 dB HL in women. The left median pure-tone thresholds at 4 kHz were 56.0 dB HL in men and 34.7 dB HL in women. Hearing acuity in 70-year-olds was not demonstrated to have changed in any consistent fashion over a 21-year time-lag. For the most recently evaluated 75-year-olds, the median PTA in the left ear was 27.3 dB HL in men and 21.6 dB in women. The left median 4 kHz threshold was 67.3 in the male group and 45.5 dB HL in the female group. Hearing in 75-year-olds over a time-lag of 14 years demonstrated somewhat better pure-tone thresholds predominantly in the men's better ear in the earliest cohort when compared to the cohort tested in 1990-91. However, there were no consistent differences of pure-tone thresholds between these age cohorts, except for the intermediate cohort 2, in which the men had generally worse hearing. Thus, there was no apparent evidence of changes of the auditory function in elderly of the same age over the last two decades. Gender-specific dissimilarities in annual pure-tone threshold deterioration between the ages of 70 and 75 were found and are discussed. PMID:9638827

Jönsson, R; Rosenhall, U; Gause-Nilsson, I; Steen, B

1998-01-01

439

Children's Judgments of Emotion from Conflicting Cues in Speech: Why 6-Year-Olds Are So Inflexible  

ERIC Educational Resources Information Center

Six-year-old children can judge a speaker's feelings either from content or paralanguage but have difficulty switching the basis of their judgments when these cues conflict. This inflexibility may relate to a lexical bias in 6-year-olds' judgments. Two experiments tested this claim. In Experiment 1, 6-year-olds (n = 40) were as inflexible when…

Waxer, Matthew; Morton, J. Bruce

2011-01-01

440

Early attachment predicts emotion recognition at 6 and 11 years old.  

PubMed

This paper reports on findings from a sample of 63 children at 6 years old, and 49 children at 11 years old, all from the same cohort who had been observed with mother in the Strange Situation at 1-year-old. At 6 and 11 years, the children responded to the task of providing verbal labels for line-drawn (caricatures of) emotion faces. The faces comprised the six basic emotions identified as such by Darwin (sadness, happiness, anger, fear, surprise, and disgust) as well as a neutral face and two more complex (blended) emotions (mischievousness and disappointment). Infant-mother attachment was linked significantly with children's emotion judgments 5 years and, to a lesser extent, 10 years after the Strange Situation assessment. Results are discussed in terms of the long-term but attenuating influence of early learning experiences in the relationship with mother, and implications for how we think about the functioning of internal working models of attachment. PMID:19016048

Steele, Howard; Steele, Miriam; Croft, Carla

2008-12-01

441

Verbal and nonverbal interactions of four- and five-year-old friends in potential conflict situations.  

PubMed

Dyads of 4- and 5-year-old friends and nonfriends attending preschools in central Italy were identified by friendship nominations. The 217 dyads of friends and non-friends participated in 2 closed-field tasks designed to simulate real-life situations of potential conflict. In the 4-year-old cohort, there were no significant differences in the behavior of the partners in either of the situations. However, at age 5 years, friends respected the rules of a fast-paced competitive game significantly more than did nonfriends. In discussing how to share a single object (a chocolate egg with a toy inside), 5-year-old friends were more likely to reach agreement than were nonfriends. The results suggest important developmental changes in the processes of negotiation and sharing within the preschool years. PMID:12230153

Tomada, Giovanna; Schneider, Barry H; Fonzi, Ada

2002-09-01

442

[Dimenhydrinate overdosage in a 3(1/2) year-old-girl with dilative cardiomyopathy].  

PubMed

Dimenhydrinate overdosage in a 3(1/2) year-old-girl with dilative cardiomyopathy. Dimenhydrinate (Vomex(R)) is frequently used in the treatment of sickness and vomiting. The symptoms of overdosage present like an anticholinergic syndrome. We report on the clinical findings of an intoxication with dimenhydrinate in a 3(1/2) year-old-girl with functional dilative cardiomyopathy following a congenital left ventricular diverticle. Especially in small children, with the application of 40 mg suppositories once or twice per day the maximum dose of 3.75 mg/kgBW/d is achieved. PMID:18240110

Girisch, M; Hofbeck, M; Rauch, R; Apitz, C; Sieverding, L

2009-01-01

443

Genetic and Environmental Influences on Frontal EEG Asymmetry and Alpha Power in 9-10 Year Old Twins  

PubMed Central

Modest genetic influences on frontal EEG asymmetry have been found in adults, but little is known about its genetic origins in children. Resting frontal asymmetry and alpha power were examined in 951 9–10-year-old twins. Results showed that in both males and females: (1) a modest but significant amount of variance in frontal asymmetry was accounted for by genetic factors (11–27%) with the remainder accounted for by non-shared environmental influences, and (2) alpha power were highly heritable, with 70–85% of the variance accounted for by genetic factors. Results suggest that the genetic architecture of frontal asymmetry and alpha power in late childhood are similar to that in adulthood and that the high non-shared environmental influences on frontal asymmetry may reflect environmentally-influenced individual differences in the maturation of frontal cortex as well as state-dependent influences on specific measurements. PMID:19386046

Gao, Yu; Tuvblad, Catherine; Raine, Adrian; Lozano, Dora I.; Baker, Laura A.

2008-01-01

444

Bilateral Leydig cell tumor in a six-year-old intersex goat affected by Polled Intersex Syndrome.  

PubMed

A 6-year-old, sterile, Blanca Celtibérica breed adult doe was referred to our faculty. The doe had external female genitalia, a short anogenital distance, and normally shaped udders. Masculinization signs in the head shape and male behavior were also noted at the time of referral. Genetic analysis demonstrated normal 2n = 60 XX karyotype and an absence of the sex-determining region Y (SRY). The animal was homozygous for a DNA deletion responsible for the Polled Intersex Syndrome (PIS). A uterus and 2 uterine horns were present at the postmortem examination. Gartner's ducts and degenerated Wolffian derivatives persisted. There were 2 intra-abdominal testicle-like structures, one of which consisted of epididymal and deferent ducts. An advanced Leydig cell tumor, resulting in almost total destruction of the intratesticular structures, was also observed. Leydig cell tumors usually produce testosterone. Thus, these histologic findings are compatible with the evident virilization. PMID:18192573

Monteagudo, L V; Arruga, M V; Bonafonte, J I; Ordás, M; Whyte, A; Gallego, M; Bascuas, J A; Sierra, I

2008-01-01

445

Encysted Spermatic Cord Hydrocele in a 60-year-old, Mimicking Incarcerated Inguinal Hernia: A Case Report  

PubMed Central

Hydrocele of spermatic cord is caused by defect in closure of the processus vaginalis, as the testicles descend into the scrotum during foetal development. It usually occurs in infancy and childhood. There are two types of hydrocele of spermatic cord. Encysted type is caused by defective closure at both proximal and distal ends of processus vaginalis and it does not communicate with the peritoneal cavity. Funicular type is caused by defective closure of only distal end of tunica vaginalis and it communicates with the peritoneal cavity. The encysted type can be confused clinically with incarcerated inguinal hernia, inguinal lymphadenopathy, undescended testis and primary tumours of cord like lipoma. We are presenting a case of encysted hydrocele of spermatic cord in a 60-year-old male, which clinically mimicked incarcerated inguinal hernia. PMID:24701514

D, Manimaran; M, Karthikeyan T; Khan, Dost Mohamed

2014-01-01

446

A case of thyrotoxic periodic paralysis as initial manifestation of Graves' disease in a 16-year-old Korean adolescent  

PubMed Central

Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism, with recurrent muscle paralysis and hypokalemia that are caused by an intracellular shift of potassium. TPP is relatively common in Asian males, but is extremely rare in children and adolescents, even for those of Asian descent. We describe a 16-year-old Korean adolescent presenting with a two-week history of episodic leg weakness in the morning. He showed sinus tachycardia, lower leg weakness, and hypokalemia. Thyroid function test showed hyperthyroidism, and thyroid ultrasonography revealed a diffuse enlarged thyroid with increased vascularity, consistent with Graves' disease. He was treated with ?-adrenergic blocker and antithyroid drugs. He has been symptom free for one year, as his hyperthyroidism has been controlled well with antithyroid drugs. TPP should be considered in children and adolescents with acute paralysis of the lower extremities and hypokalemia.

Jung, Se Yong; Song, Kyung Chul; Shin, Jae Il; Chae, Hyun Wook; Kim, Ho-Seong

2014-01-01

447

Prune-belly syndrome associated with extra-abdominal abnormalities in a 7-year-old boy.  

PubMed

Prune-belly syndrome (PBS) is an association of abdominal wall deficiency, genitourinary anomalies, and in males, cryptorchidism. Other congenital anomalies are associated with PBS, particularly musculoskeletal deformities and gastrointestinal tract anomalies. In this report, a seven-year-old boy with PBS had mega cisterna magna variant, microcornea, aortic stenosis with bicuspid aortic valves, cholelithiasis, and Hirschsprung's disease. Coexistence of these abnormalities with PBS supports the concept of PBS being caused by an early disturbance of not only mesodermal development but also of the other germ layers. There was maternal ingestion of drugs in the 1st month of gestation. All cases with PBS should be evaluated thoroughly for extra-abdominal abnormalities resulting from disturbances of ectodermal and endodermal development. Even though disturbances related to ectodermal and endodermal development may be asymptomatic, early diagnosis of the disturbances may help in preventing possible future problems. PMID:10936985

Kabaku?, N; Serhatlio?lu, S; Akfirat, M; Kazez, A; Aydino?lu, H; Ozercan, I; Aygün, A D

2000-01-01

448

A case of thyrotoxic periodic paralysis as initial manifestation of Graves' disease in a 16-year-old Korean adolescent.  

PubMed

Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism, with recurrent muscle paralysis and hypokalemia that are caused by an intracellular shift of potassium. TPP is relatively common in Asian males, but is extremely rare in children and adolescents, even for those of Asian descent. We describe a 16-year-old Korean adolescent presenting with a two-week history of episodic leg weakness in the morning. He showed sinus tachycardia, lower leg weakness, and hypokalemia. Thyroid function test showed hyperthyroidism, and thyroid ultrasonography revealed a diffuse enlarged thyroid with increased vascularity, consistent with Graves' disease. He was treated with ?-adrenergic blocker and antithyroid drugs. He has been symptom free for one year, as his hyperthyroidism has been controlled well with antithyroid drugs. TPP should be considered in children and adolescents with acute paralysis of the lower extremities and hypokalemia. PMID:25346923

Jung, Se Yong; Song, Kyung Chul; Shin, Jae Il; Chae, Hyun Wook; Kim, Ho-Seong; Kwon, Ah Reum

2014-09-01

449

Bochdalek hernia and repetitive pancreatitis in a 33 year old woman  

PubMed Central

INTRODUCTION Bochdalek hernia presentation in adulthood is rare. The presentation in newborns is the most common, manifesting with data from respiratory failure secondary to pulmonary hypoplasia, requiring urgent surgical intervention with high morbidity and mortality. PRESENTATION OF CASE We present the case of a 33 year old woman admitted in the emergency room with severe abdominal pain in the left upper quadrant and disnea. After physical examination and laboratory test we diagnose mild acute pancreatitis. The patient haven’t colelitiasis by ulstrasound or any risk factor for pancreatitis. Initially she received medical treatment and was discharged after one week. After four weeks she presented the same symptoms in two different occasions, with severe and mild pancreatitis respectively. A computed tomography report a left posterolateral diafragmatic hernia. In spite of the rare association of pancreatitis and Bochdalek hernia, we realized it as the etiology until the second event and planned his surgery. We made a posterolateral torachotomy and diafragmatic plasty with a politetrafluoroetileno mesh and after a 6 months follow up she has coursed asymptomatic. DISCUSSION The high rate of complications in this type of hernia requires us to perform surgical treatment as the hernia is detected. In this case it is prudent medical treatment prior to surgical correction despite this being the origin of the pancreatitis, because the systemic inflammatory response added by the surgical act could result in a higher rate of complications if not performed at the appropriate time. There is no precise rule to determine the type of approach of choice in this type of hernia which thoracotomy or laparotomy may be used. CONCLUSION Bochdalek hernia is a rare find in adults who require treatment immediately after diagnosis because of the high risk of complications. When presented with data from pancreatitis is recommended to complete the medical treatment of pancreatitis before surgery to obtain the best results, unless it exist another abdominal complication. PMID:25222941

Angel, Medina Andrade Luis; David, Coot Polanco Reyes; Laura, Medina Andrade; Abraham, Medina Andrade; Stephanie, Serrano Collazos; Grecia, Ortiz Ramirez

2014-01-01

450

Would Screening for Lung Cancer Benefit 75- to 84-Year-Old Residents of the United States?  

PubMed Central

Background: The National Lung Screening Trial demonstrated that screening for lung cancer improved overall survival (OS) and reduced lung cancer mortality in the 55- to 74-year-old age group by increasing the proportion of cancers detected at an early stage. Because of the increasing life expectancy of the American population, we investigated whether screening for lung cancer might benefit men and women aged 75–84?years. Materials/Methods: Rates of non-small cell lung cancer (NSCLC) from 2000 to 2009 were calculated in both younger and older age groups using the surveillance epidemiology and end reporting database. OS and lung cancer-specific survival (LCSS) in patients with Stage I NSCLC diagnosed from 2004 to 2009 were analyzed to determine the effects of age and treatment. Results: The per capita incidence of NSCLC decreased in the 55–74 cohort, but increased in the 75–84 cohort over the study period. Crude lung cancer death rates in the two age groups who had no specific treatment were 39.5 and 44.9%, respectively. These rates fell in both age groups when increasingly aggressive treatment was used. Rates of OS and LCSS improved significantly with increasingly aggressive treatment in the 75–84 age group. The survival benefits of increasingly aggressive treatment in 75- to 84-year-old females did not differ from their counterparts in the younger cohort. Conclusion: Screening for lung cancer might be of benefit to individuals at increased risk of lung cancer in the 75–84 age group. The survival benefits of aggressive therapy are similar in females between 55–74 and 75–84?years old. PMID:24639950

Varlotto, John M.; DeCamp, Malcolm M.; Flickinger, John C.; Lake, Jessica; Recht, Abram; Belani, Chandra P.; Reed, Michael F.; Toth, Jennifer W.; Mackley, Heath B.; Sciamanna, Christopher N.; Lipton, Alan; Ali, Suhail M.; Mahraj, Richkesvar P. M.; Gilbert, Christopher R.; Yao, Nengliang

2014-01-01

451

Multimodal physical therapy management of a 48-year-old female with post-stroke complex regional pain syndrome.  

PubMed

This case report describes a 48-year-old female who presented with complaints of right shoulder pain, hyperesthesias and swelling of the hand along with added symptoms of pain centralization following a cerebrovascular accident. On clinical evaluation, the patient satisfied the Budapest diagnostic criteria for Complex Regional Pain Syndrome (CRPS) type-1. Physical therapy management (1st three sessions) was initially focused on pain neurophysiology education with an aim to reduce kinesiophobia and reconceptualise her pain perception. The patient had an immediate significant improvement in her pain and functional status. Following this, pain modulation in the form of transcutaneous electrical nerve stimulation, kinesio tape application, "pain exposure" physical therapy and exercise therapy was carried out for a period of 7 weeks. The patient had complete resolution of her symptoms which was maintained at a six-month follow-up. PMID:23879307

Anandkumar, Sudarshan; Manivasagam, Murugavel

2014-01-01

452

Still dizzy after all these years: a 90-year-old woman with a 54-year history of dizziness  

PubMed Central

This report presents the case of a 90-year-old female with a 54-year history of dizziness, which has been exhaustively investigated. Over the years, the patient made 59 visits to her family doctor and 18 visits to various specialists, as well as emergency department visits and hospitalisations. In detailing the exhaustive investigations and referrals that the patient has undergone over many years (with inconclusive results), this case illustrates the myriad challenges in diagnosing and treating chronic dizziness in the older. The authors suggest that, in complex cases characterised by multimorbidity and polypharmacy, a function-oriented approach is indicated. In place of the conventional ‘diagnose and treat’ model, a functional approach to ongoing care emphasises the symptom management, improvement of function and quality of life. To optimise patient outcomes, an interprofessional team approach is preferred. PMID:22679229

Smirnova, Alina; Bell, Stephanie H; Tracy, C Shawn; Upshur, Ross EG

2011-01-01

453

Conservative treatment of a pathological fracture in a 3-year-old boy with primary hyperoxaluria type I.  

PubMed

Primary hyperoxaluria type I is a rare inherited disease that presents a disturbed metabolism of glyoxylate. Consequently, patients suffer from hyperoxaluria, leading to renal failure and subsequent skeletal calcium oxalate deposition. Areas with high concentrations of calcium oxalate, so-called dense metaphyseal bands, are at risk for pathological fracturing. The primary disease is treated by combined liver-kidney transplantation, although pathological fracturing also occurs in the posttransplant period. In the current case, we present a 3-year-old boy with a pathological fracture of his right femur, 2 years after liver-kidney transplantation. We opted for a conservative regime, leading to good fracture healing. As there are limited data in the literature regarding treatment of fractures in these patients, it is important to notify the outcome of conservative treatment of pathological fractures in patients with primary hyperoxaluria type I. PMID:22215125

Dierselhuis, Edwin F; Maathuis, Patrick G M

2013-03-01

454

[Hand replantation: differences in functional outcome considering patient age and sociomedical aspects].  

PubMed

By presenting 2 cases of successful hand replantation with similar trauma mechanism, level of amputation and ischaemia time of an 18-year-old female patient and a 48-year-old depressive male patient, the influence of age and sociomedical status on the postoperative outcome is discussed. DASH- (disabilities of the arm, shoulder and hand) score and Biometrics E-LINK power and sensitivity measurement were used to evaluate the outcomes. PMID:24357479

Reichl, H; Schütz, T; Gabl, M; Angermann, P; Russe, E; Wechselberger, G

2013-12-01

455

ADL-reduction and need for technical aids among 70-year-olds. From the population study of 70-year-olds in Göteborg.  

PubMed

Six hundred and nineteen persons from the population study of 70-year-olds "The intervention study of the elderly in Göteborg" (IVEG) were examined. They were interviewed in their home environment concerning their ability to manage activities of daily living (ADL), and the definition "ADL-reduction" is based on seven of these ADL-measurements. One third of the 70-year-old population had reduced ADL-capability, some only slightly. Joint disorders, paresis and congestive heart failure were the most common problems among the ADL-reduced subjects. Forty-three per cent of the ADL-reduced subjects (19% of total) received help with their personal care and/or housekeeping. One third had technical aid, mostly quite simple and inexpensive. Half were provided with new technical aids. The need for technical aids and home help service was noted and intervention undertaken as and when necessary. The needs were correlated to physical activity and performance in functional tests. The results do not illustrate the occurrence of handicap but are aimed at illustrating the special needs that elderly people may have in their normal surroundings. PMID:3180153

Gosman-Hedström, G; Aniansson, A; Persson, G B

1988-04-01