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1

Process for separation of zirconium-88, rubidium-83 and yttrium-88  

DOEpatents

A process for selective separation of strontium-82 and strontium-85 from proton irradiated molybdenum targets is provided and includes dissolving the molybdenum target in a hydrogen peroxide solution to form a first ion-containing solution, passing the first ion-containing solution through a first cationic resin whereby ions selected from the group consisting of molybdenum, niobium, technetium, selenium, vanadium, arsenic, germanium, zirconium and rubidium remain in the first ion-containing solution while ions selected from the group consisting of rubidium, zinc, beryllium, cobalt, iron, manganese, chromium, strontium, yttrium and zirconium are selectively adsorbed by the first resin, contacting the first resin with an acid solution capable of stripping adsorbed ions from the first cationic exchange resin whereby the adsorbed ions are removed from the first resin to form a second ion-containing solution, evaporating the second ion-containing solution for time sufficient to remove substantially all of the acid and water from the second ion-containing solution whereby a residue remains, dissolving the residue from the evaporated second-ion containing solution in a dilute acid to form a third ion-containing solution, said third ion-containing solution having an acid molarity adapted to permit said ions to be adsorbed by a cationic exchange resin, passing the third ion-containing solution through a second cationic resin whereby the ions are adsorbed by the second resin, contacting the second resin with a dilute sulfuric acid solution whereby the adsorbed ions selected from the group consisting of rubidium, zinc, beryllium, cobalt, iron, manganese, chromium, and zirconium are selectively removed from the second resin, and contacting the second resin with a dilute acid solution whereby the adsorbed strontium ions are selectively removed. Zirconium, rubidium, and yttrium radioisotopes can also be recovered with additional steps.

Heaton, Richard C. (Los Alamos, NM); Jamriska, Sr., David J. (Los Alamos, NM); Taylor, Wayne A. (Los Alamos, NM)

1994-01-01

2

(Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2004. Yttrium  

E-print Network

186 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic, and nonlinear optics. Yttrium also was used in heating-element alloys, superalloys, and high 400 400 Yttrium oxide, per kilogram, 99.0% to 99.99% purity5 25-200 22-88 22-88 22-88 52 Yttrium metal

3

(Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2005. All  

E-print Network

188 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic, superalloys, and high-temperature superconductors. The approximate distribution in 2004 by end use 400 400 400 400 400 Yttrium oxide, per kilogram, 99.0% to 99.99% purity5 22-88 22-88 22-88 10-85 10

4

(Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2006. All  

E-print Network

184 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic, superalloys, and high-temperature superconductors. The approximate distribution in 2005 by end use 298 275 326 300 300 Yttrium oxide, per kilogram, 99.0% to 99.99% purity5 22-88 22-88 22-85 10-85 10

5

Metals Fact Sheet: Yttrium  

SciTech Connect

Yttrium is a metallic element usually included among the rare earth metals, which it resembles chemically and with which it usually occurs in minerals. Yttrium was named after the village of Ytterby in Sweden---the element was discovered in a quarry near the village. This article discusses sources of the element, the world market for the element, and various applications of the material.

NONE

1992-09-01

6

Effect of pulses from a high-power ytterbium fiber laser on a material with a nonuniform refractive index. I. Irradiation of yttrium oxide targets  

NASA Astrophysics Data System (ADS)

The irradiation of Nd:Y2O3 targets with an absorption coefficient of 13-1.7 × 103 cm-1 using laser pulses with a duration of 0.1-3.5 ms and peak power of 200-700 W at a power density of (0.2-1.3) × 106 W/cm2 is studied. A relatively large spread of the delay times of laser plume, spike emission of the laser plume, cleavage of the front surface of the target, and greater ejection of substance from the crater in comparison with the effect of the CO2-laser radiation with almost the same power are demonstrated. A numerical model of the effect of radiation on a target with a nonuniform refractive index is proposed to interpret the destruction of dielectric material (cleavage of the front surface) and the large spread of the delay times of the plume.

Osipov, V. V.; Lisenkov, V. V.; Platonov, V. V.; Orlov, A. N.; Podkin, A. V.; Savvin, I. A.

2014-05-01

7

Apoferritin-Templated Yttrium Phosphate Nanoparticle Conjugates for Radioimmunotherapy of Cancers  

SciTech Connect

We report a templated-synthetic approach based on apoferritin to prepare radionuclide nanoparticle (NP) conjugates. Non-radioactive yttrium (89Y) was used as model target and surrogate for radioyttrium (90Y) to prepare the nanoparticle conjugate. The center cavity and multiple channel structure of apoferritin offer a fast and facile method to precipitate yttrium phosphate by diffusing yttrium and phosphate ions into the cavity of apofrritin, resulting a core-shell nanocomposite. The yttrium phosphate/apoferritin nanoparticle was functionalized with biotin for further application. The synthesized nanoparticle was characterized by transmission electron microscopy (TEM) and x-ray photoelectron spectroscopy (XPS). We found that the resulting nanoparticles were uniform in size, with a diameter of around 8 nm. We tested the pre-targeting capability of the biotin-modified yttrium phosphate/apoferritin nanoparticle (yttrium phosphate/apoferritin nanoparticle) conjugate with streptavidin-modified magnetic beads and with aid of biotin-modified fluorecein isothiocyanate (FITC) tracer. This work shows that an yttrium phosphate NP conjugate provides a fast, simple and efficient method to prepare radioactive yttrium conjugate for applications in radioimmunotherapy of cancer.

Wu, Hong; Wang, Jun; Wang, Zheming; Fisher, Darrell R.; Lin, Yuehe

2008-05-01

8

Combinatorial pulsed laser deposition of doped yttrium iron garnet films on yttrium aluminium garnet  

NASA Astrophysics Data System (ADS)

We investigate the crystalline growth of yttrium iron garnet (YIG) films doped with bismuth (Bi) and cerium (Ce) by combinatorial pulsed laser deposition, co-ablating a YIG target and either a Bi2O3 or a CeO2 target, for applications in microwave and optical communications. Substrate temperature is critical for crystalline growth of YIG with simultaneous inclusion of Bi in the garnet lattice, whereas Ce is not incorporated in the garnet structure, but forms a separate CeO2 phase.

Sposito, A.; Gregory, S. A.; de Groot, P. A. J.; Eason, R. W.

2014-02-01

9

Reactivity of yttrium carboxylates toward alkylaluminum hydrides.  

PubMed

Yttrocene-carboxylate complex [Cp*2Y(OOCAr(Me))] (Cp*=C5Me5, Ar(Me) =C6H2Me3-2,4,6) was synthesized as a spectroscopically versatile model system for investigating the reactivity of alkylaluminum hydrides towards rare-earth-metal carboxylates. Equimolar reactions with bis-neosilylaluminum hydride and dimethylaluminum hydride gave adduct complexes of the general formula [Cp*2Y(?-OOCAr(Me))(?-H)AlR2] (R=CH2SiMe3, Me). The use of an excess of the respective aluminum hydride led to the formation of product mixtures, from which the yttrium-aluminum-hydride complex [{Cp*2Y(?-H)AlMe2(?-H)AlMe2(?-CH3)}2] could be isolated, which features a 12-membered-ring structure. The adduct complexes [Cp*2Y(?-OOCAr(Me))(?-H)AlR2] display identical (1)J(Y,H) coupling constants of 24.5 Hz for the bridging hydrido ligands and similar (89)Y NMR shifts of ?=-88.1 ppm (R=CH2SiMe3) and ?=-86.3 ppm (R=Me) in the (89)Y DEPT45 NMR experiments. PMID:24151216

Schädle, Christoph; Fischbach, Andreas; Herdtweck, Eberhardt; Törnroos, Karl W; Anwander, Reiner

2013-11-25

10

Rare earths, the lanthanides, yttrium and scandium  

USGS Publications Warehouse

In 2005, rare earths were not mined in the United States. The major supplier, Molycorp, continued to maintain a large stockpile of rare-earth concentrates and compounds. Consumption decreased of refined rare-earth products. The United States remained a major importer and exporter of rare earths in 2005. During the same period, yttrium was not mined or refined in the US. Hence, supply of yttrium compounds for refined yttrium products came from China, France and Japan. Scandium was not also mined. World production was primarily in China, Russia and Ukraine. Demand for rare earths in 2006 is expected to be closely tied to economic conditions in the US.

Hedrick, J.B.

2006-01-01

11

Rare earths, the lanthanides, yttrium and scandium  

USGS Publications Warehouse

In 2011, rare earths were recovered from bastnasite concentrates at the Mountain Pass Mine in California. Consumption of refined rare-earth products decreased in 2011 from 2010. U.S. rare-earth imports originated primarily from China, with lesser amounts from Austria, Estonia, France and Japan. The United States imported all of its demand for yttrium metal and yttrium compounds, with most of it originating from China. Scandium was imported in various forms and processed domestically.

Bedinger, G.; Bleiwas, D.

2012-01-01

12

Yttrium hydride nanoantennas for active plasmonics  

NASA Astrophysics Data System (ADS)

A key challenge for the development of active plasmonic nanodevices is the lack of materials with fully controllable plasmonic properties. In this work, we demonstrate that a plasmonic resonance in top-down nanofabricated yttrium antennas can be completely and reversibly turned on and off using hydrogen exposure. We fabricate arrays of yttrium nanorods and optically observe in extinction spectra the hydrogen-induced phase transition between the metallic yttrium dihydride and the insulating trihydride. Whereas the yttrium dihydride nanostructures exhibit a pronounced particle plasmon resonance, the transition to yttrium trihydride leads to a complete vanishing of the resonant behavior. The plasmonic resonance in the dihydride state can be tuned over a wide wavelength range by simply varying the size of the nanostructures. Furthermore, we develop an analytical diffusion model to explain the temporal behaviour of the hydrogen loading and unloading process observed in our experiments and gain information about the thermodynamics of our device. Thus, our nanorod system serves as a versatile basic building block for active plasmonic devices ranging from switchable perfect absorbers to active local heating control elements.

Strohfeldt, Nikolai; Tittl, Andreas; Schäferling, Martin; Neubrech, Frank; Kreibig, Uwe; Griessen, Ronald; Giessen, Harald

2014-09-01

13

Cerium and yttrium oxide nanoparticles are neuroprotective  

Microsoft Academic Search

The responses of cells exposed to nanoparticles have been studied with regard to toxicity, but very little attention has been paid to the possibility that some types of particles can protect cells from various forms of lethal stress. It is shown here that nanoparticles composed of cerium oxide or yttrium oxide protect nerve cells from oxidative stress and that the

David. Schubert; Richard Dargusch; Joan Raitano; Siu-Wai Chan

2006-01-01

14

Low energy cyclotron production and separation of yttrium-86 for evaluation of monoclonal antibody pharmacokinetics and dosimetry  

NASA Astrophysics Data System (ADS)

Although an excellent radionuclide for application to systemic isotopic therapy when complexed to various monoclonal antibodies, the lack of photon emission from yttrium-90 makes the determination of the pharmacokinetics and dosimetry of the resultant radiopharmaceutical difficult. The introduction of the positron-emitting radionuclide yttrium-86 (T1/2=14.7 h, ?+=33%) provides the non-invasive quantitation for the biodistribution of the chelated complex. The yttrium-86 radionuclide is produced at Memorial Sloan-Kettering using the CS-15 cyclotron via the (p,n) nuclear reaction on an enriched strontium-86 target. The separation is effectively achieved through a combination of solvent extraction and ion exchange chromatography. Once investigational new drug approval has been received, the mixed nuclides, Y-90 and Y-86, are to be used to formulate the HuM195 labeled monoclonal antibody, a radiopharmaceutical under active investigation against hematopoietic progenitor cells.

Finn, R. D.; McDevitt, M.; Ma, D.; Jurcic, J.; Scheinberg, D.; Larson, S.; Shoner, S.; Link, J.; Krohn, K.; Schlyer, D.

1999-06-01

15

Yttrium90 DOTATOC: first clinical results  

Microsoft Academic Search

.   In a pilot study, DOTA-d-Phe1-Tyr3-octreotide (DOTATOC), which can be labelled with the ?-emitting radioisotope yttrium-90, has recently been used for the treatment\\u000a of patients with advanced somatostatin receptor-positive tumours who had no other treatment option. The aim of the present\\u000a study was to elucidate the therapeutic potential of 90Y-DOTATOC in a larger number of patients employing a standardized treatment

A. Otte; R. Herrmann; A. Heppeler; M. Behe; E. Jermann; P. Powell; H. R. Maecke; J. Muller

1999-01-01

16

Safety of Repeated Yttrium-90 Radioembolization  

SciTech Connect

Purpose: Repeated radioembolization (RE) treatments carry theoretically higher risk of radiation-induced hepatic injury because of the liver's cumulative memory of previous exposure. We performed a retrospective safety analysis on patients who underwent repeated RE. Methods: From 2004 to 2011, a total of 247 patients were treated by RE. Eight patients (5 men, 3 women, age range 51-71 years) underwent repeated treatment of a targeted territory, all with resin microspheres (SIR-Spheres; Sirtex, Lane Cove, Australia). Adverse events were graded during a standardized follow-up. In addition, the correlation between the occurrence of RE-induced liver disease (REILD) and multiple variables was investigated in univariate and multivariate analyses in all 247 patients who received RE. Results: Two patients died shortly after the second treatment (at 84 and 107 days) with signs and symptoms of REILD. Both patients underwent whole liver treatment twice (cumulative doses 3.08 and 2.66 GBq). The other 6 patients demonstrated only minor toxicities after receiving cumulative doses ranging from 2.41 to 3.88 GBq. All patients experienced objective tumor responses. In the whole population, multifactorial analysis identified three risk factors associated with REILD: repeated RE (p = 0.036), baseline serum total bilirubin (p = 0.048), and baseline serum aspartate aminotransferase (p = 0.043). Repeated RE proved to be the only independent risk factor for REILD in multivariate analysis (odds ratio 9.6; p = 0.002). Additionally, the administered activity per target volume (in GBq/L) was found to be an independent risk factor for REILD, but only in whole liver treatments (p = 0.033). Conclusion: The risk of REILD appears to be elevated for repeated RE. Objective tumor responses were observed, but establishment of safety limits will require improvement in dosimetric measurement and prediction.

Lam, Marnix G. E. H.; Louie, John D. [Stanford University School of Medicine, Division of Interventional Radiology (United States)] [Stanford University School of Medicine, Division of Interventional Radiology (United States); Iagaru, Andrei H.; Goris, Michael L. [Stanford University School of Medicine, Division of Nuclear Medicine (United States)] [Stanford University School of Medicine, Division of Nuclear Medicine (United States); Sze, Daniel Y., E-mail: dansze@stanford.edu [Stanford University School of Medicine, Division of Interventional Radiology (United States)

2013-10-15

17

Cerium and yttrium oxide nanoparticles are neuroprotective  

SciTech Connect

The responses of cells exposed to nanoparticles have been studied with regard to toxicity, but very little attention has been paid to the possibility that some types of particles can protect cells from various forms of lethal stress. It is shown here that nanoparticles composed of cerium oxide or yttrium oxide protect nerve cells from oxidative stress and that the neuroprotection is independent of particle size. The ceria and yttria nanoparticles act as direct antioxidants to limit the amount of reactive oxygen species required to kill the cells. It follows that this group of nanoparticles could be used to modulate oxidative stress in biological systems.

Schubert, David [Salk Institute, 10010 N. Torrey Pines Rd., La Jolla, CA 92037 (United States)]. E-mail: schubert@salk.edu; Dargusch, Richard [Salk Institute, 10010 N. Torrey Pines Rd., La Jolla, CA 92037 (United States); Raitano, Joan [Columbia University, Departments of Applied Physics and Applied Mathematics, 1136 Mudd, MC 4701, New York, NY 10027 (United States); Chan, S.-W. [Columbia University, Departments of Applied Physics and Applied Mathematics, 1136 Mudd, MC 4701, New York, NY 10027 (United States)

2006-03-31

18

Safety of knee radiosynovectomy with yttrium - 90  

NASA Astrophysics Data System (ADS)

Radioisotope knee synovectomy is based on an Yttrium - 90 citrate injection (185 - 222 MBq) into the knee joint cavity. The performance of procedure needs participation of a nuclear medicine specialist as well as an orthopedist or a rheumatologist and a technologist, who prepares radiopharmaceuticals. The ionization doses for patients and personnel depend not only on the injected activity, but also on the method and process of injection and the radioactivity measurement procedure used. The aim of this study is the evaluation of the degree of radiation exposure of patients and medical personnel during the performance of therapy with 90Y.

Kempi?ska, M.; Lass, P.; ?wik?a, J. B.; ?bikowski, P.

2011-09-01

19

(Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2003.  

E-print Network

186 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic, and nonlinear optics. Yttrium also was used in heating-element alloys, superalloys, and high for consumption: In monazite (yttrium oxide contente ) -- -- -- -- -- Yttrium compounds, greater than 19% to less

20

(Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was mined as a constituent of the mineral bastnasite,  

E-print Network

184 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic, and nonlinear optics. Yttrium was also used in heating-element alloys, superalloys, and high for consumption: In monazite (yttrium oxide contente ) 1.11 0.22 -- -- -- Yttrium compounds, greater than 19

21

(Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic Production and Use: The rare-earth element, yttrium, was mined as a constituent of the mineral  

E-print Network

188 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic, and nonlinear optics. Yttrium was also used in heating-element alloys, superalloys, and high: In monazite (yttrium oxide contente ) 0.44 1.11 0.22 -- -- Yttrium compounds, greater than 19% to less than 85

22

(Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was mined as a constituent of the mineral bastnasite  

E-print Network

186 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic, and nonlinear optics. Yttrium was also used in heating-element alloys, superalloys, and high -- -- -- -- -- Imports for consumption: In monazite (yttrium oxide contente ) 0.22 -- -- -- -- Yttrium compounds, greater

23

49 CFR 393.88 - Television receivers.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Television receivers. 393.88 Section 393.88 Transportation Other Regulations Relating to...SAFE OPERATION Miscellaneous Parts and Accessories § 393.88 Television receivers. Any motor vehicle...

2010-10-01

24

29 CFR 1915.88 - Sanitation.  

...2014-07-01 2014-07-01 false Sanitation. 1915.88 Section 1915.88 ...General Working Conditions § 1915.88 Sanitation. (a) General requirements. ...provide adequate and readily accessible sanitation facilities. (2) The...

2014-07-01

25

29 CFR 1915.88 - Sanitation.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Sanitation. 1915.88 Section 1915.88 ...General Working Conditions § 1915.88 Sanitation. (a) General requirements. ...provide adequate and readily accessible sanitation facilities. (2) The...

2013-07-01

26

29 CFR 1915.88 - Sanitation.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Sanitation. 1915.88 Section 1915.88 ...General Working Conditions § 1915.88 Sanitation. (a) General requirements. ...provide adequate and readily accessible sanitation facilities. (2) The...

2012-07-01

27

Hickey, TT162, Casts 88-92 Hickey, TT162, Casts 88-92, page 1  

E-print Network

Hickey, TT162, Casts 88-92 Hickey, TT162, Casts 88-92, page 1 CTD088 #12;Hickey, TT162, Casts 88-92 Hickey, TT162, Casts 88-92, page 2 CTD088 #12;Hickey, TT162, Casts 88-92 Hickey, TT162, Casts 88-92, page 3 CTD088 #12;Hickey, TT162, Casts 88-92 Hickey, TT162, Casts 88-92, page 4 CTD088 #12;Hickey, TT162

Hickey, Barbara

28

Rare-earth elements, yttrium, and thorium. A materials survey  

Microsoft Academic Search

Survey type information is presented on rare earths, yttrium, and thorium. Chapters with references are included on properties and uses, historical notes, resources, technology, supply and distribution, industrial structure, research and development, and strategic factors. (JRD)

J. G. Parker; C. T. Baroch

1971-01-01

29

STS-88 Mating in VAB  

NASA Technical Reports Server (NTRS)

The orbiter Endeavour is suspended in a vertical position inside the Vehicle Assembly Building where it will be mated with its solid rocket boosters and external tank. Endeavour is scheduled to fly on mission STS-88, the first Space Shuttle flight for the assembly of the International Space Station, on December 3, 1998. The primary payload on the mission is the Unity connecting module, which will be mated to the Russian-built Zarya Control Module already in orbit at that time.

1998-01-01

30

STS-88 Day 06 Highlights  

NASA Technical Reports Server (NTRS)

On this sixth day of the STS-88 mission, the flight crew, Commander Robert D. Cabana, Pilot Frederick W. Sturckow, and Mission Specialists Nancy J. Currie, James H. Newman, Jerry L. Ross, and Sergei Krikalev are awakened by Dwight Yokum's "Streets of Bakersfield," requested by the wife of Pilot Rick Sturckow, a California native. Cabana and Sturckow fire Endeavour's primary reaction control jets to raise the altitude of the International Space Station by about 5-1/2 statute miles. Later on Cabana, Sturckow and Currie are interviewed by the ABC News/Discovery Channel and MSNBC.

1998-01-01

31

PET Imaging of Soluble Yttrium-86-Labeled Carbon Nanotubes in Mice  

PubMed Central

Background The potential medical applications of nanomaterials are shaping the landscape of the nanobiotechnology field and driving it forward. A key factor in determining the suitability of these nanomaterials must be how they interface with biological systems. Single walled carbon nanotubes (CNT) are being investigated as platforms for the delivery of biological, radiological, and chemical payloads to target tissues. CNT are mechanically robust graphene cylinders comprised of sp2-bonded carbon atoms and possessing highly regular structures with defined periodicity. CNT exhibit unique mechanochemical properties that can be exploited for the development of novel drug delivery platforms. In order to evaluate the potential usefulness of this CNT scaffold, we undertook an imaging study to determine the tissue biodistribution and pharmacokinetics of prototypical DOTA-functionalized CNT labeled with yttrium-86 and indium-111 (86Y-CNT and 111In-CNT, respectively) in a mouse model. Methodology and Principal Findings The 86Y-CNT construct was synthesized from amine-functionalized, water-soluble CNT by covalently attaching multiple copies of DOTA chelates and then radiolabeling with the positron-emitting metal-ion, yttrium-86. A gamma-emitting 111In-CNT construct was similarly prepared and purified. The constructs were characterized spectroscopically, microscopically, and chromatographically. The whole-body distribution and clearance of yttrium-86 was characterized at 3 and 24 hours post-injection using positron emission tomography (PET). The yttrium-86 cleared the blood within 3 hours and distributed predominantly to the kidneys, liver, spleen and bone. Although the activity that accumulated in the kidney cleared with time, the whole-body clearance was slow. Differential uptake in these target tissues was observed following intraveneous or intraperitoneal injection. Conclusions The whole-body PET images indicated that the major sites of accumulation of activity resulting from the administration of 86Y-CNT were the kidney, liver, spleen, and to a much less extent the bone. Blood clearance was rapid and could be beneficial in the use of short-lived radionuclides in diagnostic applications. PMID:17878942

Jaggi, Jaspreet S.; Finn, Ronald D.; Zanzonico, Pat B.; Villa, Carlos; Rey, Diego; Mendenhall, Juana; Batt, Carl A.; Njardarson, Jon T.; Scheinberg, David A.

2007-01-01

32

Scandium versus yttrium{amino-alkoxy-bis(phenolate)} complexes for the stereoselective ring-opening polymerization of racemic lactide and ?-butyrolactone.  

PubMed

Scandium and yttrium amide complexes Ln{ONXO(R1,R2)}(N(SiHMe2)2)(THF)n (Ln = Sc, n = 0 or Y, n = 1; X = NMe2 or OMe; R(1) = Cumyl or p-Cl-Cumyl; R(2) = Me or Cumyl) were prepared by aminolysis of Ln[N(SiHMe2)2]3(THF) with the corresponding tetradentate diamino- or alkoxy-amino-bis(phenol) pro-ligands {ONXO(R1,R2)}H2. In the solid state and in toluene solution, the scandium complexes are monomeric and 5-coordinated, while the analogous yttrium complexes all bear an extra THF-coordinated molecule and are 6-coordinated. Sc{ONXO(R1,R2)}(N(SiHMe2)2) complexes are single-site initiators for the ring-opening polymerization (ROP) of racemic lactide but are less active than their yttrium analogues Y{ONXO(R1,R2)}(N(SiHMe2)2)(THF); also, in contrast to the latter ones, they are inactive in the ROP of the more demanding racemic ?-butyrolactone. On the other hand, the scandium amide complexes feature a significantly improved control over the ROP of lactide, yielding PLAs with much narrower molecular weight distributions (?(M) < 1.1 for Sc vs. 1.5-2.0 for Y). The yttrium complex with the very bulky o,p-dicumyl-substituted ligand is more heteroselective than its scandium analogue (P(r) = 0.88 vs. 0.83), while the opposite is observed with complexes based on p-methyl-substituted ligands (P(r) = 0.50 in toluene or 0.72-0.75 in THF for Y vs. P(r) = 0.75-0.83 for Sc in toluene). These reactivity and selectivity trends are rationalized by a much more sterically crowded coordination sphere in scandium than in yttrium complexes. PMID:24886860

Chapurina, Yulia; Klitzke, Joice; Casagrande, Osvaldo de L; Awada, Mouhamad; Dorcet, Vincent; Kirillov, Evgueni; Carpentier, Jean-François

2014-10-14

33

Tungsten - Yttrium Based Nuclear Structural Materials  

NASA Astrophysics Data System (ADS)

The challenging problem currently facing the nuclear science community in this 21st century is design and development of novel structural materials, which will have an impact on the next-generation nuclear reactors. The materials available at present include reduced activation ferritic/martensitic steels, dispersion strengthened reduced activation ferritic steels, and vanadium- or tungsten-based alloys. These materials exhibit one or more specific problems, which are either intrinsic or caused by reactors. This work is focussed towards tungsten-yttrium (W-Y) based alloys and oxide ceramics, which can be utilized in nuclear applications. The goal is to derive a fundamental scientific understanding of W-Y-based materials. In collaboration with University of Califonia -- Davis, the project is designated to demonstrate the W-Y based alloys, ceramics and composites with enhanced physical, mechanical, thermo-chemical properties and higher radiation resistance. Efforts are focussed on understanding the microstructure, manipulating materials behavior under charged-particle and neutron irradiation, and create a knowledge database of defects, elemental diffusion/segregation, and defect trapping along grain boundaries and interfaces. Preliminary results will be discussed.

Ramana, Chintalapalle; Chessa, Jack; Martinenz, Gustavo

2013-04-01

34

40 CFR 763.88 - Assessment.  

...88 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Asbestos-Containing Materials in Schools § 763.88 Assessment. (a)(1) For each inspection and...

2014-07-01

35

48 CFR 1352.271-88 - Guarantees.  

Code of Federal Regulations, 2012 CFR

...271-88 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 1352.271-88 Guarantees. As prescribed in 48 CFR...

2012-10-01

36

48 CFR 1352.271-88 - Guarantees.  

Code of Federal Regulations, 2010 CFR

...271-88 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 1352.271-88 Guarantees. As prescribed in 48 CFR...

2010-10-01

37

48 CFR 1352.271-88 - Guarantees.  

Code of Federal Regulations, 2011 CFR

...271-88 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 1352.271-88 Guarantees. As prescribed in 48 CFR...

2011-10-01

38

48 CFR 1352.271-88 - Guarantees.  

Code of Federal Regulations, 2013 CFR

...271-88 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 1352.271-88 Guarantees. As prescribed in 48 CFR...

2013-10-01

39

32 CFR 644.88 - Other acquisition.  

Code of Federal Regulations, 2010 CFR

... 2010-07-01 2010-07-01 true Other acquisition. 644.88 Section 644.88 National Defense...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Acquisition Acquisition by Purchase, Donation, and Transfer §...

2010-07-01

40

50 CFR 260.88 - Political activity.  

Code of Federal Regulations, 2011 CFR

50 Wildlife and Fisheries 9 2011-10-01 2011-10-01...activity. 260.88 Section 260.88 Wildlife and Fisheries NATIONAL MARINE FISHERIES...Establishments and Fishery Products for Human Consumption Miscellaneous §...

2011-10-01

41

50 CFR 260.88 - Political activity.  

Code of Federal Regulations, 2012 CFR

50 Wildlife and Fisheries 11 2012-10-01 ...activity. 260.88 Section 260.88 Wildlife and Fisheries NATIONAL MARINE FISHERIES...Establishments and Fishery Products for Human Consumption Miscellaneous §...

2012-10-01

42

50 CFR 260.88 - Political activity.  

Code of Federal Regulations, 2013 CFR

50 Wildlife and Fisheries 11 2013-10-01 ...activity. 260.88 Section 260.88 Wildlife and Fisheries NATIONAL MARINE FISHERIES...Establishments and Fishery Products for Human Consumption Miscellaneous §...

2013-10-01

43

50 CFR 260.88 - Political activity.  

Code of Federal Regulations, 2010 CFR

50 Wildlife and Fisheries 7 2010-10-01 2010-10-01...activity. 260.88 Section 260.88 Wildlife and Fisheries NATIONAL MARINE FISHERIES...Establishments and Fishery Products for Human Consumption Miscellaneous §...

2010-10-01

44

40 CFR 721.10177 - Phosphoric acid, yttrium(3+) salt (1:1).  

Code of Federal Regulations, 2012 CFR

...Phosphoric acid, yttrium(3+) salt (1:1). 721.10177 ...Phosphoric acid, yttrium(3+) salt (1:1). (a) Chemical...phosphoric acid, yttrium(3+) salt (1:1) (PMN P-04-153...f). (ii) Release to water . Requirements as...

2012-07-01

45

40 CFR 721.10177 - Phosphoric acid, yttrium(3+) salt (1:1).  

Code of Federal Regulations, 2013 CFR

...false Phosphoric acid, yttrium(3+) salt (1:1). 721.10177 Section 721...10177 Phosphoric acid, yttrium(3+) salt (1:1). (a) Chemical substance...identified as phosphoric acid, yttrium(3+) salt (1:1) (PMN P-04-153; CAS...

2013-07-01

46

40 CFR 721.10013 - Manganese yttrium oxide (Mn2YO5).  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Manganese yttrium oxide (Mn2YO5). 721.10013...Chemical Substances § 721.10013 Manganese yttrium oxide (Mn2 YO5 ). ...The chemical substance identified as manganese yttrium oxide (Mn2 YO5 )...

2013-07-01

47

40 CFR 721.10009 - Manganese yttrium oxide (MnYO3).  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Manganese yttrium oxide (MnYO3). 721.10009...Chemical Substances § 721.10009 Manganese yttrium oxide (MnYO3). (a) Chemical...The chemical substance identified as manganese yttrium oxide (MnYO3 ) (PMN...

2010-07-01

48

40 CFR 721.10009 - Manganese yttrium oxide (MnYO3).  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Manganese yttrium oxide (MnYO3). 721.10009...Chemical Substances § 721.10009 Manganese yttrium oxide (MnYO3 ). (a...The chemical substance identified as manganese yttrium oxide (MnYO3 ) (PMN...

2013-07-01

49

40 CFR 721.10013 - Manganese yttrium oxide (Mn2YO5).  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Manganese yttrium oxide (Mn2YO5). 721.10013...Chemical Substances § 721.10013 Manganese yttrium oxide (Mn2 YO5 ). ...The chemical substance identified as manganese yttrium oxide (Mn2 YO5 )...

2012-07-01

50

40 CFR 721.10009 - Manganese yttrium oxide (MnYO3).  

...2014-07-01 2014-07-01 false Manganese yttrium oxide (MnYO3). 721.10009...Chemical Substances § 721.10009 Manganese yttrium oxide (MnYO3 ). (a...The chemical substance identified as manganese yttrium oxide (MnYO3 ) (PMN...

2014-07-01

51

40 CFR 721.10009 - Manganese yttrium oxide (MnYO3).  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Manganese yttrium oxide (MnYO3). 721.10009...Chemical Substances § 721.10009 Manganese yttrium oxide (MnYO3). (a) Chemical...The chemical substance identified as manganese yttrium oxide (MnYO3 ) (PMN...

2011-07-01

52

40 CFR 721.10013 - Manganese yttrium oxide (Mn2YO5).  

...2014-07-01 2014-07-01 false Manganese yttrium oxide (Mn2YO5). 721.10013...Chemical Substances § 721.10013 Manganese yttrium oxide (Mn2 YO5 ). ...The chemical substance identified as manganese yttrium oxide (Mn2 YO5 )...

2014-07-01

53

40 CFR 721.10009 - Manganese yttrium oxide (MnYO3).  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Manganese yttrium oxide (MnYO3). 721.10009...Chemical Substances § 721.10009 Manganese yttrium oxide (MnYO3 ). (a...The chemical substance identified as manganese yttrium oxide (MnYO3 ) (PMN...

2012-07-01

54

40 CFR 721.10013 - Manganese yttrium oxide (Mn2YO5).  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Manganese yttrium oxide (Mn2YO5). 721.10013...Chemical Substances § 721.10013 Manganese yttrium oxide (Mn2YO5). (a...The chemical substance identified as manganese yttrium oxide (Mn2 YO5 )...

2010-07-01

55

40 CFR 721.10013 - Manganese yttrium oxide (Mn2YO5).  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Manganese yttrium oxide (Mn2YO5). 721.10013...Chemical Substances § 721.10013 Manganese yttrium oxide (Mn2YO5). (a...The chemical substance identified as manganese yttrium oxide (Mn2 YO5 )...

2011-07-01

56

STS-88 Day 03 Highlights  

NASA Technical Reports Server (NTRS)

On this third day of the STS-88 mission, the flight crew, Commander Robert D. Cabana, Pilot Frederick W. Sturckow, and Mission Specialists Nancy J. Currie, James H. Newman, Jerry L. Ross, and Sergei Krikalev check out the various tools they will use during the three scheduled spacewalks to be conducted later in the flight. They then begin an early set-up of the Shuttle's airlock in preparation for that first spacewalk. Newman and Russian cosmonaut Sergei Krikalev take part in an on-line interview by the New York Times. Currie is seen placing Unity just inches above the extended outer ring on Endeavour's docking mechanism, enabling Commander Bob Cabana to fire downward maneuvering jets to lock the shuttle's docking system to one of two Pressurized Mating Adapters (PMA's) attached to Unity.

1998-01-01

57

STS-88 Day 04 Highlights  

NASA Technical Reports Server (NTRS)

On this forth day of the STS-88 mission, the flight crew, Commander Robert D. Cabana, Pilot Frederick W. Sturckow, and Mission Specialists Nancy J. Currie, James H. Newman, Jerry L. Ross, and Sergei are awakened to the sounds of "Somewhere Over the Rainbow," requested by Commander Bob Cabana's daughter, Sarah. With the three-story-high Unity connecting module latched upright in the shuttle's payload bay, Cabana takes manual control of the shuttle as it moves to within about a half-mile of Zarya. Cabana and Sturckow execute a sequence of maneuvers that will bring Endeavour directly above the module. Currie uses the robotic arm to capture the module. She then positions Zarya above Unity's docking mechanism.

1998-01-01

58

Synthesis and chemistry of yttrium and lanthanide metal complexes  

SciTech Connect

The objective of this research project is to determine the special features of complexes of yttrium and the lanthanide metals which will allow the design and synthesis of materials with unique chemical, physical, and catalytic properties. Past studies of yttrium and lanthanide metal alkyl and hydride complexes stabilized by cyclopentadienyl co-ligands have shown that a substantial, often singular, organometallic chemistry is available via these metals. More extensive utilization of the chemical opportunities available through yttrium and the lanthanides would be possible, however, if stabilizing ancillary ligand systems less sensitive to oxidation and protonolysis than cyclopentadienides could be developed. Alkoxide ligands are attractive in this regard and our recent research had focused on alkoxides and the special opportunities they can provide to these metals. 6 refs., 10 figs.

Evans, W.J.

1991-09-01

59

(Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was mined as a constituent of the mineral bastnsite  

E-print Network

188 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content, unless otherwise noted) Domestic, superalloys, and high-temperature superconductors. The approximate distribution in 2001 by end use -- -- -- -- -- Imports for consumption: In monazite (yttrium oxide contente ) -- -- -- -- -- Yttrium compounds, greater

60

(Data in metric tons of yttrium oxide (Y2O3) content, unless noted) Domestic Production and Use: The rare-earth element, yttrium, was mined by one company as a constituent of the  

E-print Network

186 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content, unless noted) Domestic, superalloys, and high-temperature superconductors. The approximate distribution in 1995 by end use-267 Yttrium concentrate, per kilogram, 60% REO 32-33 32-33 NA NA NA Yttrium oxide, per kilogram, 99.0% to 99

61

(Data in metric tons of yttrium oxide (Y O ) content, unless otherwise noted)2 3 Domestic Production and Use: The rare-earth element, yttrium, was mined as a constituent of the mineral bastnasite,  

E-print Network

190 YTTRIUM1 (Data in metric tons of yttrium oxide (Y O ) content, unless otherwise noted)2 3, superalloys, and high- temperature superconductors. The approximate distribution in 1997 by end use -- -- -- -- Imports for consumption: In monazite (yttrium oxide content ) -- 0.44 1.11 0.22 --e Yttrium compounds

62

Hydrothermal crystal growth of yttrium and rare earth stabilized hafnia  

NASA Astrophysics Data System (ADS)

Single crystals of hafnia stabilized with yttrium, neodymium, holmium and erbium 0.25 mm in size were formed in hydrothermal solutions by spontaneous nucleation in 20 M KOH at 750 °C. Positive transport conditions were established at 650 °C using a single crystal of cubic zirconia as a substrate for growth of yttrium stabilized hafnia at a rate of 0.084 mm/week. During the study single crystals could only be formed with high concentrations of the stabilizer dopants by this method. This is the lowest synthesis temperature reported for any single crystal growth method of this refractory material.

Mann, Matthew; Kolis, Joseph

2010-01-01

63

WSR-88D Cell Trends  

NASA Technical Reports Server (NTRS)

This report documents the Applied Meteorology Unit's evaluation of the Cell Trends display as a tool for radar operators to use in their evaluation of storm cell strength. The objective of the evaluation is to assess the utility of the WSR-88D graphical Cell Trends display for local radar cell interpretation in support of the 45th Weather Squadron (45 WS), Spaceflight Meteorology Group (SMG), and National Weather Service (NWS) Melbourne (MLB) operational requirements. The analysis procedure was to identify each cell and track the maximum reflectivity, height of maximum reflectivity, storm top, storm base, hail and severe hail probability, cell-based Vertically Integrated Liquid (VIL) and core aspect ratio using WATADS Build 9.0 cell trends information. One problem noted in the analysis phase was that the Storm Cell Identification and Tracking (SCIT) algorithm had a difficult time tracking the small cells associated with the Florida weather regimes. The analysis indicated numerous occasions when a cell track would end or an existing cell would be give a new ID in the middle of its life cycle. This investigation has found that most cells, which produce hail or microburst events, have discernable Cell Trends signatures. Forecasters should monitor the PUP's Cell Trends display for cells that show rapid (1 scan) changes in both the heights of maximum reflectivity and cell-based VIEL. It is important to note that this a very limited data set (four case days). Fifty-two storm cells were analyzed during those four days. The above mentioned t=ds, increase in the two cell attributes for hail events and decrease in the two cell attributes for wind events were noted in most of the cells. The probability of detection was 88% for both events. The False Alarm Rate (FAR) was a 36% for hail events and a respectable 25% for microburst events. In addition the Heidke Skill Score (HSS) is 0.65 for hail events and 0.67 for microburst events. For random forecast the HSS is 0 and that a perfect score is 1.

Wheeler, Mark M.

1998-01-01

64

STS-88 Day 11 Highlights  

NASA Technical Reports Server (NTRS)

On this eleventh day of the STS-88 mission, the flight crew, Commander Robert D. Cabana, Pilot Frederick W. Sturckow, and Mission Specialists Nancy J. Currie, James H. Newman, Jerry L. Ross, and Sergei Krikalev are awakened with the song "Goodnight, Sweetheart, Goodnight". Pilot Rick Sturckow undocks Endeavour from the station and backs the shuttle away to a distance of 450 feet above the station before beginning a nose-forward fly-around. Later Cabana, Sturckow and Ross deploy the SAC-A satellite from Endeavour's payload bay. SAC-A is a small, self-contained, non-recoverable satellite built by the Argentinean National Commission of Space Activities. The cube-shaped, 590-pound satellite will test and characterize the performance of new equipment and technologies that may be used in future scientific or operational missions. The payload includes a differential global positioning system, a magnetometer, silicon solar cells, a charge-coupled device Earth camera and a whale tracker experiment.

1998-01-01

65

STS-88 Day 10 Highlights  

NASA Technical Reports Server (NTRS)

On this tenth day of the STS-88 mission, the flight crew, Commander Robert D. Cabana, Pilot Frederick W. Sturckow, and Mission Specialists Nancy J. Currie, James H. Newman, Jerry L. Ross, and Sergei Krikalev are awakened by the sounds of Elvis Presley's "Hound Dog". Today's activities are devoted mostly to tasks that ready the station for future assembly work. The crew's first job is to release some cable ties on four cables connected on an earlier space walk, three located on Unity's upper mating adapter and one on its lower adapter, to relieve tension on the lines. The space walkers also will check an insulation cover on one cable connection on the lower Pressurized Mating Adapter (PMA 2) to make sure it is fully installed. Near the end of the space walk, the astronauts conduct a detailed photographic survey of the space station from top to bottom. Finally, each astronaut test fires the Simplified Aid for Extravehicular Activity Rescue (SAFER) jet backpacks they are wearing, a type of space "lifejacket," that would allow an astronaut to fly back to the station if they should ever become untethered.

1998-01-01

66

Discovery of Yttrium, Zirconium, Niobium, Technetium, and Ruthenium Isotopes  

E-print Network

Currently, thirty-four yttrium, thirty-five zirconium, thirty-four niobium, thirty-five technetium, and thirty-eight ruthenium isotopes have been observed and the discovery of these isotopes is discussed here. For each isotope a brief synopsis of the first refereed publication, including the production and identification method, is presented.

A. Nystrom; M. Thoennessen

2011-02-11

67

First-principles study of intrinsic defects in yttrium oxysulfide  

NASA Astrophysics Data System (ADS)

Atomic and electronic structures of intrinsic point defects in yttrium oxysulfides (Y2O2S) are studied by first-principles total-energy calculations based on density-functional theory combined with normconserving pseudopotentials. Energetics of all the intrinsic point defects are determined for a variety of charge states. From the energetics, the concentrations of the anion vacancies and the interstitial anions are found to be larger than those of the yttrium vacancy and the interstitial yttrium atom under practical conditions. It is also found that the oxygen vacancy, the sulfur vacancy, and the interstitial sulfur atom induce relatively deep levels in the energy gap, whereas the interstitial oxygen atom induces relatively shallow acceptor levels. These findings are consistent with observed broad-band blue luminescence in undoped yttrium oxysulfide, existence of shallow acceptor levels in oxysulfides, and are presumably related to persistent phosphorescence and energy storage phenomena in Eu-doped oxysulfides. Furthermore, negative-U characters are found in the oxygen vacancy and the interstitial sulfur. These behaviors of the defects can be explained from the viewpoint of the covalent bonds newly appearing around the defects in the ionic host material.

Mikami, Masayoshi; Oshiyama, Atsushi

1999-07-01

68

Evidence of yttrium silicate inclusions in YSZ-porcelain veneers.  

PubMed

This report introduces the discovery of crystalline defects that can form in the porcelain veneering layer when in contact with yttria-stabilized zirconia (YSZ). The focus was on dental prostheses and understanding the defects that form in the YSZ/porcelain system; however the data reported herein may have broader implications toward the use and stability of YSZ-based ceramics in general. Specimens were cut from fully sintered YSZ plates and veneering porcelain was applied (<1 mm thick) to one surface and fired under manufacturer's recommended protocol. Scanning electron microscopy (SEM) with integrated electron dispersive X-ray (EDAX) was used for microstructural and elemental analysis. EDAX, for chemical analysis and transmission electron diffraction (TED) for structural analysis were both performed in the transmission electron microscope (TEM). Additionally, in order to spatially resolve Y-rich precipitates, micro-CT scans were conducted at varying depths within the porcelain veneer. Local EDAX (SEM) was performed in the regions of visible inclusions and showed significant increases in yttrium concentration. TEM specimens also showed apparent inclusions in the porcelain and selected area electron diffraction was performed on these regions and found the inclusions to be crystalline and identified as either yttrium-silicate (Y2 SiO5 ) or yttrium-disilicate (Y2 Si2 O7 ). Micro-CT data showed that yttrium-silicate precipitates were distributed throughout the thickness of the porcelain veneer. Future studies are needed to determine whether many of the premature failures associated with this materials system may be the result of crystalline flaws that form as a result of high temperature yttrium diffusion near the surfaces of YSZ. PMID:24106151

Stoner, Brian R; Griggs, Jason A; Neidigh, John; Piascik, Jeffrey R

2014-04-01

69

7 CFR 3570.88 - Management assistance.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 false Management assistance. 3570...Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance....

2013-01-01

70

7 CFR 3570.88 - Management assistance.  

...2014-01-01 false Management assistance. 3570...Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance....

2014-01-01

71

7 CFR 3570.88 - Management assistance.  

Code of Federal Regulations, 2011 CFR

...2011-01-01 false Management assistance. 3570...Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance....

2011-01-01

72

7 CFR 3570.88 - Management assistance.  

Code of Federal Regulations, 2010 CFR

...2010-01-01 false Management assistance. 3570...Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance....

2010-01-01

73

7 CFR 3570.88 - Management assistance.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 false Management assistance. 3570...Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance....

2012-01-01

74

Post-radioembolization yttrium-90 PET/CT - part 1: diagnostic reporting  

PubMed Central

Background Yttrium-90 (90Y) positron emission tomography with integrated computed tomography (PET/CT) represents a technological leap from 90Y bremsstrahlung single-photon emission computed tomography with integrated computed tomography (SPECT/CT) by coincidence imaging of low abundance internal pair production. Encouraged by favorable early experiences, we implemented post-radioembolization 90Y PET/CT as an adjunct to 90Y bremsstrahlung SPECT/CT in diagnostic reporting. Methods This is a retrospective review of all paired 90Y PET/CT and 90Y bremsstrahlung SPECT/CT scans over a 1-year period. We compared image resolution, ability to confirm technical success, detection of non-target activity, and providing conclusive information about 90Y activity within targeted tumor vascular thrombosis. 90Y resin microspheres were used. 90Y PET/CT was performed on a conventional time-of-flight lutetium-yttrium-oxyorthosilicate scanner with minor modifications to acquisition and reconstruction parameters. Specific findings on 90Y PET/CT were corroborated by 90Y bremsstrahlung SPECT/CT, 99mTc macroaggregated albumin SPECT/CT, follow-up diagnostic imaging or review of clinical records. Results Diagnostic reporting recommendations were developed from our collective experience across 44 paired scans. Emphasis on the continuity of care improved overall diagnostic accuracy and reporting confidence of the operator. With proper technique, the presence of background noise did not pose a problem for diagnostic reporting. A counter-intuitive but effective technique of detecting non-target activity is proposed, based on the pattern of activity and its relation to underlying anatomy, instead of its visual intensity. In a sub-analysis of 23 patients with a median follow-up of 5.4 months, 90Y PET/CT consistently outperformed 90Y bremsstrahlung SPECT/CT in all aspects of qualitative analysis, including assessment for non-target activity and tumor vascular thrombosis. Parts of viscera closely adjacent to the liver remain challenging for non-target activity detection, compounded by a tendency for mis-registration. Conclusions Adherence to proper diagnostic reporting technique and emphasis on continuity of care are vital to the clinical utility of post-radioembolization 90Y PET/CT. 90Y PET/CT is superior to 90Y bremsstrahlung SPECT/CT for the assessment of target and non-target activity. PMID:23883566

2013-01-01

75

Radioimmunotherapy in non-Hodgkin's lymphoma: trials of yttrium 90-labeled ibritumomab tiuxetan and beyond.  

PubMed

The treatment for non-Hodgkin's lymphoma (NHL) has improved over the past 20 years, but the natural history of the disease has not improved with conventional therapeutics. New modalities using targeted therapy based on molecular biology and immunology hold promise for better outcomes with less toxicity. Major radionuclides available (iodine I 131 and yttrium 90) are discussed and clinical trial data with the 90Y-labeled antibody ibritumomab tiuxetan are presented. Long-term toxicity questions are addressed, the use of dosimetry as a means for predicting toxicity is reviewed, and quality-of-life analyses are discussed. Radioimmunotherapy represents a safe and effective treatment modality for patients with NHL. PMID:15498144

Evens, Andrew M; Gordon, Leo I

2004-10-01

76

Highly Efficient Tm-Doped Yttrium Aluminum Garnet Ceramic Laser Based on the Novel Fiber-Bulk Hybrid Configuration  

NASA Astrophysics Data System (ADS)

A polycrystalline ceramic Tm3+-doped yttrium aluminum garnet (Tm:Y3Al5O12, Tm:YAG) laser based on the novel fiber-bulk hybrid configuration is demonstrated using a high-power and tunable Er,Yb co-doped fiber laser as the pump source. Lasing characteristics of a 4.0 at. % Tm:YAG ceramic are investigated at different pump wavelengths from 1617 to 1625 nm. With an output coupler of 10% transmission, a maximum output power of 3.9 W is obtained at 2013.2 nm under an 8.8 W incident pump power at the Tm:YAG absorption peak of 1620.4 nm, corresponding to a slope efficiency of 50.1% with respect to the incident pump power.

Liu, Jun; Shen, Deyuan; Huang, Haitao; Zhang, Xiaoqi; Tang, Dingyuan; Fan, Dianyuan

2013-09-01

77

YTTRIUM ALUMINATE CERAMIC FIBERS VIA PRE-CERAMIC POLYMER AND SOL-GEL ROUTES  

Microsoft Academic Search

Yttrium aluminum garnet (YAG - Y3Al5O12) fibers have been prepared by dry spinning solutions of yttrium and aluminum carboxylate polymers (precursor route) and by dry spinning aqueous oxide sols (sol-gel route). Fibers from aqueous diphasic gels are prepared by mixing a colloidal alumina sol containing 50-nm hydrous alumina with a colloidal yttria sol containing 10-nm yttrium oxide, using polyvinylpyrrolidone as

BRUCE KING; YIN LIU; SURESH BASKARAN; RICHARD LAINE; JOHN HALLORAN

1992-01-01

78

Effects of yttrium and zinc substitutions in Bi-2212  

NASA Astrophysics Data System (ADS)

In this work, resistivity measurements of Bi 2Sr 2Ca 1- xY xCu 2- yZn yO 8+ d were analyzed. The yttrium substitution on calcium site modifies the charge concentration and the zinc substitution on cupper site leads to a depression of the superconducting transition temperature TC. Beyond the superconducting transition, the resistivity curves show the compounds evolve from a metallic state to a semi-conducting state upon the yttrium and zinc substitutions. The semi-conductive behavior is explained by a random distribution of the substituted element. The evolution of the linear resistivity upon doping confirms the presence of heterogeneities. Moreover, the results suggest that zinc lead to a more effective states localization and stripes pinning.

Pignon, Bruno; Autret-Lambert, Cécile; Ruyter, Antoine; Monot-Laffez, Isabelle; Ammor, Larbi

2007-09-01

79

Gadolinium and Yttrium Borates: Thermal Behavior and Structural Considerations  

Microsoft Academic Search

The present work deals with the phase diagram of the Gd2O3–B2O3 binary system where three solid phases with respective stoichiometries Gd3BO6, GdBO3, and Gd(BO2)3 have been evidenced. MAS NMR experiments were performed using similar yttrium compounds. Only BIV sites exist in orthoborate at room temperature and the transition phase observed at about 900°C has to be attributed to the change

M. Th. Cohen-Adad; O. Aloui-Lebbou; C. Goutaudier; G. Panczer; C. Dujardin; C. Pedrini; P. Florian; D. Massiot; F. Gerard; Ch. Kappenstein

2000-01-01

80

Thermal Decomposition of Lanthanide, Yttrium, and Scandium Oxalates and Carbonates  

NASA Astrophysics Data System (ADS)

Data concerning the thermal decomposition of lanthanide, yttrium, and scandium oxalates and carbonates are surveyed. The complexity of the process, the large number of stages involved, and the dependence of the composition of the intermediates in the thermal transformations on the experimental conditions is noted. Certain process characteristics have been discovered and it is concluded that the decomposition process depends on the ionic radius of the metal. The bibliography includes 83 references.

Sharov, Vyacheslav A.; Bezdenezhnykh, G. V.

1981-07-01

81

37 CFR 1.88 - [Reserved  

Code of Federal Regulations, 2010 CFR

...TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions The Drawings § 1.88 [Reserved] Models, Exhibits, Specimens Authority: Secs. 1.91 to 1.95 also issued under 35...

2010-07-01

82

32 CFR 88.3 - Definitions.  

Code of Federal Regulations, 2011 CFR

...DEFENSE PERSONNEL, MILITARY AND CIVILIAN TRANSITION ASSISTANCE FOR MILITARY PERSONNEL § 88.3...under the Job Training Partnership Act as described in section...102-484; continued use of military family housing...

2011-07-01

83

32 CFR 88.3 - Definitions.  

Code of Federal Regulations, 2013 CFR

...DEFENSE PERSONNEL, MILITARY AND CIVILIAN TRANSITION ASSISTANCE FOR MILITARY PERSONNEL § 88.3...under the Job Training Partnership Act as described in section...102-484; continued use of military family housing...

2013-07-01

84

32 CFR 88.3 - Definitions.  

Code of Federal Regulations, 2012 CFR

...DEFENSE PERSONNEL, MILITARY AND CIVILIAN TRANSITION ASSISTANCE FOR MILITARY PERSONNEL § 88.3...under the Job Training Partnership Act as described in section...102-484; continued use of military family housing...

2012-07-01

85

32 CFR 88.3 - Definitions.  

Code of Federal Regulations, 2010 CFR

...DEFENSE PERSONNEL, MILITARY AND CIVILIAN TRANSITION ASSISTANCE FOR MILITARY PERSONNEL § 88.3...under the Job Training Partnership Act as described in section...102-484; continued use of military family housing...

2010-07-01

86

7 CFR 984.88 - Agents.  

Code of Federal Regulations, 2010 CFR

... AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE WALNUTS GROWN IN CALIFORNIA Order Regulating Handling Miscellaneous Provisions § 984.88 Agents. The Secretary may,...

2010-01-01

87

42 CFR 88.2 - General provisions.  

Code of Federal Regulations, 2012 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.2 General provisions. (a) Designated representative. (1) An applicant,...

2012-10-01

88

42 CFR 88.2 - General provisions.  

Code of Federal Regulations, 2011 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.2 General provisions. (a) Designated representative. (1) An applicant,...

2011-10-01

89

42 CFR 88.2 - General provisions.  

Code of Federal Regulations, 2013 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.2 General provisions. (a) Designated representative. (1) An applicant,...

2013-10-01

90

42 CFR 88.1 - Definitions.  

Code of Federal Regulations, 2012 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.1 Definitions. List of WTC-Related Health Conditions (4) Cancers:...

2012-10-01

91

H2 oxidation on doped yttrium chromites/yttrium stabilized zirconia anode of solid oxide fuel cell  

NASA Astrophysics Data System (ADS)

Co and Ni doped yttrium chromites as potential anodes for solid oxide fuel cell (SOFC) are studied with respect to the electrode performance and anode reaction mechanisms. Both electrical conductivity and electrode performance of yttrium chromites have been enhanced after Co and Ni doping. Electrochemical impedance spectroscopy (EIS) results indicate that charge transfer process at high frequency and surface adsorption/diffusion processes at low frequency domain can be the dominant anode reaction steps. Ni doping accelerates the surface processes by reducing the related activation energy from 1.2 to 0.5 eV. It also substantially improves the charge transfer process probably by increasing the amount of adsorbed H on electrode surface. The resistance of high frequency is found to be dependent on H2 content. The observed reaction order is 1/4 for Co doped and 1/3-1/2 for Ni doped yttrium chromites. A model of H2 oxidation reaction is proposed, revealing this dependence stems from the reaction between adsorbed H and the lattice oxygen.

Li, Wenyuan; Gong, Mingyang; Liu, Xingbo

2013-11-01

92

(Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2007. All  

E-print Network

188 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic, superalloys, and high-temperature superconductors. The approximate distribution in 2006 by end use: Monazite concentrate, per metric ton4 275 326 300 300 300 Yttrium oxide, per kilogram, 99.0% to 99

93

(Data in metric tons of yttrium oxide (Y O ) content, unless otherwise noted)2 3 Domestic Production and Use: The rare-earth element, yttrium, was mined by one company as a constituent of the  

E-print Network

188 YTTRIUM1 (Data in metric tons of yttrium oxide (Y O ) content, unless otherwise noted)2 3, superalloys, and high- temperature superconductors. The approximate distribution in 1995 by end use-272 222-259 237-277 Yttrium oxide, per kilogram, 99.0% to 99.99% purity 15-116 16-116 20-116 17-110 17

94

(Data in metric tons of yttrium oxide (Y O ) content, unless otherwise noted)2 3 Domestic Production and Use: The rare-earth element, yttrium, was mined by one company as a constituent of the  

E-print Network

188 YTTRIUM1 (Data in metric tons of yttrium oxide (Y O ) content, unless otherwise noted)2 3, superalloys, and high-temperature superconductors. The approximate distribution in 1996 by end use, per metric ton 204-238 233-272 222-259 244-285 224-262 Yttrium oxide, per kilogram, 99.0% to 99

95

Speciation of adsorbed yttrium and rare earth elements on oxide surfaces  

E-print Network

Speciation of adsorbed yttrium and rare earth elements on oxide surfaces Wojciech Piasecki, Dimitri 10 June 2008 Abstract The distribution of yttrium and the rare earth elements (YREE) between natural investigate the applicability of the X-ray results to rare earth elements and to several oxides in addition

Sverjensky, Dimitri A.

96

Process for recovering yttrium and lanthanides from wet-process phosphoric acid  

SciTech Connect

Process for recovering yttrium and lanthanides from wet-process phosphoric acid by adding a flocculant to the phosphoric acid, separating out the resultant precipitate and then recovering yttrium and lanthanides from the precipitate. Uranium is recovered from the remaining phosphoric acid.

Janssen, J.A.; Weterings, C.A.

1983-06-28

97

Novel Synergistic Agent for Selective Separation of Yttrium from Other Rare Earth Metals  

Microsoft Academic Search

An oil-soluble synergistic agent has been developed for the selective separation of yttrium (Y) from the other rare earth metals. The synergistic agent is a polyaminocarboxylic acid alkylderivative and has interfacial activity like that of surfactants. Separation of yttrium from heavy rare earth metals [erbium (Er) and holmium (Ho)] in the presence of the synergistic agent was carried out with

Terufumi Miyata; Masahiro Goto; Fumiyuki Nakashio

1995-01-01

98

Atomistic Modeling of Native Point Defects in Yttrium Aluminum Garnet Crystals  

E-print Network

for the purpose of exploiting its potential in high-temperature applications.11­13 The diffusion and defectAtomistic Modeling of Native Point Defects in Yttrium Aluminum Garnet Crystals Maija M. Kuklja point defects in yttrium aluminum garnet (YAG) are studied in the framework of the pair

Pandey, Ravi

99

Thermal stability studies of plasma sprayed yttrium oxide coatings deposited on pure tantalum substrate  

Microsoft Academic Search

Plasma sprayed Yttrium oxide is used for coating of crucibles and moulds that are used at high temperature to handle highly reactive molten metals like uranium, titanium, chromium, and beryllium. The alloy bond layer is severely attacked by the molten metal. This commonly used layer contributes to the impurity addition to the pure liquid metal. Yttrium oxide was deposited on

Nagaraj A; Anupama P; Jaya Mukherjee; Sreekumar K P; R U Satpute; P V A Padmanabhan; L M Gantayet

2010-01-01

100

RBS and GAXRD contributions to yttrium implanted extra low carbon steel characterization  

SciTech Connect

Extra low carbon steel samples were yttrium implanted using an ion implantation method. Composition and structural studies were carried out before and after yttrium implantations by several analytical and structural techniques (Rutherford backscattering spectrometry, reflection high energy electron diffraction, scanning electron microscopy, X-ray diffraction, and glancing angle X-ray diffraction) to characterize the yttrium implantation effect on extra low carbon steel. The aim of this article is to show the contributions of Rutherford back-scattering spectrometry (RBS) and glancing angle X-ray diffraction (GAXRD) to the determination of yttrium depth profiles in the samples. The results obtained by these techniques are compared to those of the other analyses performed in this work to show the existing correlation between composition and structural studies. Their results allow a better understanding of the effect of yttrium implantation in extra low carbon steel before studying their corrosion resistance at high temperature.

Caudron, E.; Buscail, H. [Equipe Locale Univ. Blaise Pascal Clermont-Fd II, Le Puy en Velay (France). Lab. Vellave d`Elaboration et d`Etude des Materiaux] [Equipe Locale Univ. Blaise Pascal Clermont-Fd II, Le Puy en Velay (France). Lab. Vellave d`Elaboration et d`Etude des Materiaux; Jacob, Y.P.; Stroosnijder, M.F. [European Commission, Ispra (Italy). Inst. for Advanced Materials] [European Commission, Ispra (Italy). Inst. for Advanced Materials

1999-02-01

101

Concentration and temperature dependences of the oxygen migration energy in yttrium-stabilized zirconia  

NASA Astrophysics Data System (ADS)

The ionic conductivity of zirconia with different contents of the yttrium stabilizing impurity has been studied using impedance spectroscopy in the temperature range 300-910°C. A deviation of the temperature dependence of the conductivity in the crystallite bulk from the Arrhenius equation has been revealed. A quantum-mechanics estimation of the influence of the yttrium content on the oxygen-vacancy migration barrier as a function of its distance to the yttrium atom has been carried out. A two-barrier mechanism of the dependence of the oxygen migration energy on the yttrium content in zirconia due to anion vacancy trapping by yttrium has been proposed. Analytical dependences of the concentration of free (active) anion vacancies and the activation energy of ionic conductivity on the temperature and stabilizing impurity content have been obtained.

Tokiy, N. V.; Perekrestov, B. I.; Savina, D. L.; Danilenko, I. A.

2011-09-01

102

Defect-Property Correlations in Garnet Crystals. *VII: The Electrical Conductivity and Defect Structure of Yttrium Aluminum and Yttrium Iron Garnet Solid Solutions  

Microsoft Academic Search

The conduction mechanisms in yttrium aluminum and yttrium iron garnet solid solutions have been studied as a function of temperature, iron concentration and partial pressure of oxygen. At low concentrations of iron, ac conductivity and ionic transference measurements show the solid solution to be a mixed ionic-electronic conductor with an ionic mobility characterized by an activation energy of 2.6–2.8?eV and

S. R. Rotman; H. L. Tuller

1998-01-01

103

Enhanced spin pumping at yttrium iron garnet/Au interfaces  

SciTech Connect

Spin injection across the ferrimagnetic insulator yttrium iron garnet (YIG)/normal metal Au interface was studied using ferromagnetic resonance. The spin mixing conductance was determined by comparing the Gilbert damping parameter {alpha} in YIG/Au and YIG/Au/Fe heterostructures. The main purpose of this study was to correlate the spin pumping efficiency with chemical modifications of the YIG film surface using in situ etching and deposition techniques. By means of Ar{sup +} ion beam etching, one is able to increase the spin mixing conductance at the YIG/Au interface by a factor of 5 compared to the untreated YIG/Au interface.

Burrowes, C.; Heinrich, B.; Kardasz, B.; Montoya, E. A.; Girt, E. [Physics Department, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6 (Canada); Sun Yiyan; Song, Young-Yeal; Wu Mingzhong [Physics Department, Colorado State University, Fort Collins, Colorado 80523 (United States)

2012-02-27

104

Damping in Yttrium Iron Garnet Nanoscale Films Capped by Platinum  

NASA Astrophysics Data System (ADS)

Strong damping enhancement in nm-thick yttrium iron garnet (YIG) films due to Pt capping layers was observed. This damping is substantially larger than the expected damping due to conventional spin pumping, is accompanied by a shift in the ferromagnetic resonance field, and can be suppressed by the use of a Cu spacer in between the YIG and Pt films. The data indicate that such damping may originate from the ferromagnetic ordering in Pt atomic layers near the YIG/Pt interface and the dynamic exchange coupling between the ordered Pt spins and the spins in the YIG film.

Sun, Yiyan; Chang, Houchen; Kabatek, Michael; Song, Young-Yeal; Wang, Zihui; Jantz, Michael; Schneider, William; Wu, Mingzhong; Montoya, E.; Kardasz, B.; Heinrich, B.; te Velthuis, Suzanne G. E.; Schultheiss, Helmut; Hoffmann, Axel

2013-09-01

105

47 CFR 80.88 - Secrecy of communication.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 false Secrecy of communication. 80.88 Section 80.88 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY...Procedures-General § 80.88 Secrecy of communication. The station licensee,...

2011-10-01

106

29 CFR 1960.88 - Membership and participation.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 false Membership and participation. 1960.88 Section 1960.88 Labor Regulations Relating to Labor (Continued...MATTERS Field Federal Safety and Health Councils § 1960.88 Membership and participation....

2010-07-01

107

29 CFR 1960.88 - Membership and participation.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 false Membership and participation. 1960.88 Section 1960.88 Labor Regulations Relating to Labor (Continued...MATTERS Field Federal Safety and Health Councils § 1960.88 Membership and participation....

2011-07-01

108

29 CFR 1960.88 - Membership and participation.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 false Membership and participation. 1960.88 Section 1960.88 Labor Regulations Relating to Labor (Continued...MATTERS Field Federal Safety and Health Councils § 1960.88 Membership and participation....

2012-07-01

109

47 CFR 80.88 - Secrecy of communication.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 false Secrecy of communication. 80.88 Section 80.88 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY...Procedures-General § 80.88 Secrecy of communication. The station licensee,...

2010-10-01

110

40 CFR 282.88 - Pennsylvania State-Administered Program.  

...2014-07-01 false Pennsylvania State-Administered Program. 282.88 Section 282.88 Protection of...CONTINUED) APPROVED UNDERGROUND STORAGE TANK PROGRAMS Approved State Programs § 282.88 Pennsylvania...

2014-07-01

111

28 CFR 115.88 - Data review for corrective action.  

Code of Federal Regulations, 2012 CFR

...for corrective action. 115.88 Section 115.88 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Data Collection and Review § 115.88...

2012-07-01

112

28 CFR 115.88 - Data review for corrective action.  

Code of Federal Regulations, 2013 CFR

...for corrective action. 115.88 Section 115.88 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Data Collection and Review § 115.88...

2013-07-01

113

Temporary Arterial Balloon Occlusion as an Adjunct to Yttrium-90 Radioembolization  

SciTech Connect

Purpose. This study was designed to describe the technique of arterial occlusion using a temporary occlusion balloon system as an alternative to coil occlusion during Yttrium-90 radioembolization of hepatic tumors. Methods. Review of charts, angiography, and follow-up imaging studies of consecutive patients undergoing oncological embolization procedures in which a HyperForm system (ev3 Neurovascular, Irvine, CA) was used. Intraprocedural target vessel occlusion and patency of the target vessel on follow-up were recorded. Clinical data and Bremsstrahlung scans were reviewed for evidence of nontarget embolization. Results. Four radioembolization procedures were performed in three patients (all female, age 48-54 (mean 52) years). Five arteries were temporarily occluded (three gastroduodenal arteries, one right gastric artery, and one cystic artery). All radioembolization procedures were successfully completed. Follow-up imaging (either digital subtraction angiography (DSA) or computed tomography angiography (CTA)) was available for all patients between 28-454 (mean 183) days following the procedure, demonstrating all five vessels to be patent. No clinical or imaging evidence for nontarget embolization was found. Conclusions. Temporary balloon occlusion of small and medium-sized arteries during radioembolization allows safe therapy with preserved postprocedural vessel patency on early and midterm follow-up.

Hagspiel, Klaus D., E-mail: kdh2n@virginia.edu [University of Virginia Health System, Department of Radiology and Medical Imaging (United States); Nambiar, Ashwin, E-mail: uvashwin@gmail.com [SUNY Downstate Medical Center, Department of Radiology (United States); Hagspiel, Lauren M., E-mail: lmh4gg@virginia.edu [University of Virginia, College of Arts and Sciences (United States); Ahmad, Ehab Ali, E-mail: ehabradiodiagnosis@yahoo.com [Minia University, Department of Radiology (Egypt); Bozlar, Ugur, E-mail: ubozlar@yahoo.com [Gulhane Military Medical Academy, Department of Radiology (Turkey)

2013-06-15

114

Magnetism in Mo-doped Yttrium Iron Garnet  

NASA Astrophysics Data System (ADS)

Yttrium iron garnet (YIG) is a synthetic garnet and ferrimagnetic, with chemical formula Y3Fe5O12. In YIG, five iron (III) ions occupy two octahedral and three tetrahedral sites, with the yttrium (III) ions coordinated by eight oxygen ions in an irregular cube. The iron ions in the two coordination sites exhibit different spins, resulting in magnetic behavior. Bulk YIG has been synthesized systematically by solid state reaction method. The formation of pure YIG have been investigated through X-ray diffraction (XRD) beginning from weighing in molar proportions of Y2O3 and Fe2O3, mixing and grinding, pre-sintering and final sintering at 1300 ^oC. XRD study shows that YIG exhibits cubic structure with lattice constant of about 12 å. Magnetization with varying field and temperature has been measured using a SQUID magnetometer. Magnetic measurement of Mo YIG has shown that magnetic moment increase initially and then decreases with Mo doping. Detailed results will be discussed in this presentation. This work is supported by National Science Foundation (Award Number DMR-0907037).

Khanra, S.; Kolekar, Y.; Langhoff, M.; Kahol, P.; Ghosh, K.

2013-03-01

115

Rare earth and yttrium phosphate solubilities in aqueous solution  

NASA Astrophysics Data System (ADS)

Rare earth and yttrium phosphate solubility products range over more than 1 order of magnitude. Minimum solubilities are observed for light rare earths between Ce and Sm. For the elements Ce, Pr, Nd, and Sm solubility products (log Ksp0 ( M) = log ([ Mi3+] [PO 43-])) at zero ionic strength and 25°C can be approximated as log Ksp0,( M) = -26.3 ± 0.2. Rare earth phosphate solubility products for well-aged, coarse precipitates increase substantially between Sm and Lu, with log Ksp0(Lu) estimated as -24.7. The solubility product of Y is similar to that of Ho (log Ksp0 (Y) = -25.0) and is much higher than those of all light rare earths. The solubility product of La is substantially larger than that of Cc (log Ksp 0(La) - log Ksp0 (Ce) ? 0.5). Solubility products are strongly dependent on the conditions of solid phase formation. Fresh precipitates are much more soluble than slowly formed, well-aged, coarse precipitates. The pattern of rare earth and yttrium phosphate solubility products is generally similar to the fractionation patterns which are developed during phosphate coprecipitation.

Liu, Xuewu; Byrne, Robert H.

1997-04-01

116

Yttrium oxide based three dimensional metamaterials for visible light cloaking  

NASA Astrophysics Data System (ADS)

Metamaterial with negative refractive index is the key phenomenon behind the concept of a cloaking device to hide an object from light in visible spectrum. Metamaterials made of two and three dimensional lattices of periodically placed electromagnetic resonant cells can achieve absorption and propagation of incident electromagnetic radiation as confined electromagnetic fields confined to a waveguide as surface plasmon polaritons, which can be used for shielding an object from in-tune electromagnetic radiation. The periodicity and dimensions of resonant cavity determine the frequency, which are very small as compared to the wavelength of incident light. Till now the phenomena have been demonstrated only for lights in near infrared spectrum. Recent advancements in fabrication techniques have made it possible to fabricate array of three dimensional nanostructures with cross-sections as small as 25 nm that are required for negative refractive index for wavelengths in visible light spectrum of 400-700 nm and for wider view angle. Two types of metamaterial designs, three dimensional concentric split ring and fishnet, are considered. Three dimensional structures consisted of metal-dielectric-metal stacks. The metal is silver and dielectric is yttrium oxide, other than conventional materials such as FR4 and Duroid. High ? dielectric and high refractive index as well as large crystal symmetry of Yttrium oxide has been investigated as encapsulating medium. Dependence of refractive index on wavelength and bandwidth of negative refractive index region are analyzed for application towards cloaking from light in visible spectrum.

Rai, Pratyush; Kumar, Prashanth S.; Varadan, Vijay K.; Ruffin, Paul; Brantley, Christina; Edwards, Eugene

2014-04-01

117

Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88  

Microsoft Academic Search

Staphylococcal enterotoxin B (SEB) exposure triggers an exaggerated pro-inflammatory cytokine response that often leads to toxic shock syndrome (TSS) associated with organ failure and death. MyD88 mediates pro-inflammatory cytokine signaling induced by SEB exposure and MyD88?\\/? mice are resistant to SEB intoxication, suggesting that MyD88 may be a potential target for therapeutic intervention. We targeted the BB loop region of

Teri L. Kissner; Gordon Ruthel; Shahabuddin Alam; Enrique Mann; Dariush Ajami; Mitra Rebek; Eileen Larkin; Stefan Fernandez; Robert G. Ulrich; Sun Ping; David S. Waugh; Julius Rebek; Kamal U. Saikh

2012-01-01

118

Nanomechanical and optical properties of yttrium thin films by magnetron sputtering.  

PubMed

This Letter reports on nanomechanical and optical properties of yttrium thin films deposited on an Si (100) wafer. Elemental depth profiling by a secondary ion mass spectrometer revealed absence of formation of yttrium hydride, both on the surface and beneath. The optical properties were investigated by spectroscopic ellipsometry, and the refractive indices extracted after suitable modeling were found to be 2.51 at 546 nm. Hardness and elastic modulus of these films were found to be 7 and 142 GPa, respectively. These studies indicate that yttrium thin films are suitable for x-ray mirrors, photocathode emitters in e-beam lithography, electron microscopes, and free-electron lasers. PMID:24875983

Ramaseshan, R; Sundari, S Tripura; Balamurugan, A K; Dash, Sitaram; Tyagi, A K; Sato, Y; Nakayama, T; Suematsu, H

2014-06-01

119

Treatment of exhaust fluorescent lamps to recover yttrium: Experimental and process analyses  

SciTech Connect

Highlights: > Recovery of yttrium from spent fluorescent lamps by sulphuric acid leaching. > The use of sulphuric acid allows to reduce calcium dissolutions. > Main contaminant of fluorescent powder are Si, Pb, Ca and Ba. > Hydrated yttrium oxalate, recovered by selective precipitation, is quite pure (>90%). > We have studied the whole process for the treatment of dangerous waste (plant capability). - Abstract: The paper deals with recovery of yttrium from fluorescent powder coming from dismantling of spent fluorescent tubes. Metals are leached by using different acids (nitric, hydrochloric and sulphuric) and ammonia in different leaching tests. These tests show that ammonia is not suitable to recover yttrium, whereas HNO{sub 3} produces toxic vapours. A full factorial design is carried out with HCl and H{sub 2}SO{sub 4} to evaluate the influence of operating factors. HCl and H{sub 2}SO{sub 4} leaching systems give similar results in terms of yttrium extraction yield, but the last one allows to reduce calcium extraction with subsequent advantage during recovery of yttrium compounds in the downstream. The greatest extraction of yttrium is obtained by 20% w/v S/L ratio, 4 N H{sub 2}SO{sub 4} concentration and 90 deg. C. Yttrium and calcium yields are nearly 85% and 5%, respectively. The analysis of variance shows that acid concentration alone and interaction between acid and pulp density have a significant positive effect on yttrium solubilization for both HCl and H{sub 2}SO{sub 4} medium. Two models are empirically developed to estimate yttrium and calcium concentration during leaching. Precipitation tests demonstrate that at least the stoichiometric amount of oxalic acid is necessary to recover yttrium efficiently and a pure yttrium oxalate n-hydrate can be produced (99% grade). The process is economically feasible if other components of the fluorescent lamps (glass, ferrous and non-ferrous scraps) are recovered after the equipment dismantling and valorized, besides the cost that is usually paid to recycling companies for collection, treatment or final disposal of such fluorescent powders.

De Michelis, Ida, E-mail: ida.demichelis@univaq.it [University of L'Aquila, Department of Chemistry, Chemical Engineering and Materials - Ex-Optimes Loc., Campo di Pile, 67100 L'Aquila (Italy); Ferella, Francesco, E-mail: francesco.ferella@univaq.it [University of L'Aquila, Department of Chemistry, Chemical Engineering and Materials - Ex-Optimes Loc., Campo di Pile, 67100 L'Aquila (Italy); Varelli, Ennio Fioravante [University of L'Aquila, Department of Chemistry, Chemical Engineering and Materials - Ex-Optimes Loc., Campo di Pile, 67100 L'Aquila (Italy); Veglio, Francesco, E-mail: francesco.veglio@univaq.it [University of L'Aquila, Department of Chemistry, Chemical Engineering and Materials - Ex-Optimes Loc., Campo di Pile, 67100 L'Aquila (Italy)

2011-12-15

120

Mass spectroscopic characterization of yttrium-containing metallofullerene YC82 using resonant laser ablation  

SciTech Connect

In this paper, resonant laser ablation time-of-flight mass spectroscopy (RLA-TOF-MS) has been used to mass spectroscopic characterization of yttrium-containing fullerenes. Solvent soluble, yttrium-containing fullerenes are extracted from yttrium/carbon soot produced by the carbon-arc fullerene generation method. The RLA-TOF mass spectra indicate the presence of YC82. The metallofullerences YC60, YC70, Y2C82 and a series of Y2C2n are not observed by RLA-TOF-MS. This result is consistent with the ESR spectral result reported by Shinohara et al.

Wang Shiliang; Tian Jiahe; Dai Songtao; Chen Dieyan; Luo Chuping; Tan Haisong; Gan Liangbing; Huang Chunhui [Laser Single Atom Detection Laboratory, Department of Physics, Tsinghua University, Beijing 100084 (China); State Key Laboratory of Rare Earth Material Chemistry and Applications, Peking University, Beijing 100871 (China)

1995-04-01

121

Nickel hexa-yttrium deca-iodide, [NiY6]I10.  

PubMed

Comproportionation reactions of yttrium triiodide, yttrium and nickel led to the formation of the compound [NiY6]I10, which is isostructural with the prototypical [RuY6]I10. In particular, [NiY6]I10 is composed of isolated nickel centered yttrium octa-hedra (site symmetry -1) that are further surrounded by iodide ligands to construct a three-dimensional cluster complex framework. Although this compound has been previously detected by powder X-ray diffraction techniques [Payne & Corbett (1990 ?). Inorg. Chem. 29, 2246-2251], details of the crystal structure for triclinic [NiY6]I10 were not provided. PMID:24940186

Steinberg, Simon; Meyer, Gerd

2014-06-01

122

Measurements of High Energy Neutron Spectrum (> 10 MeV) by Using Yttrium Foils in a U/Pb Assembly  

NASA Astrophysics Data System (ADS)

Study of deep subcritical electronuclear systems and radioactive waste transmutation using relativistic beams were performed. This work is a preliminary step toward the study of the physical properties of Accelerator Driven Systems, in which a deeply subcritical active core is irradiated by a pulsed beam of relativistic ions. The long-range goal of the project is to study the capabilities of such systems with a hard neutron spectrum, for transmutation of radioactive nuclear wastes. Two experimental assemblies, “Energy plus Transmutation” (2006-2009) and “Quinta” (2011-), were irradiated by 1 to 6 GeV deuteron beams using the JINR NUCLOTRON accelerator. The main difference between the two experimental setups is the spallation target - lead or natural uranium. We attempt to obtain neutron energy spectra inside the volume of these assemblies using threshold reactions in natural yttrium (89Y) foils. Some results from three different experiments are presented.

Bielewicz, M.; Strugalska-Gola, E.; Szuta, M.; Wojciechowski, A.; Kadykov, M.; Tyutyunnikov, S.

2014-05-01

123

Growth of different phases of yttrium manganese oxide thin films by pulsed laser deposition  

SciTech Connect

Various phases of yttrium manganese oxide (YMO) thin films have been synthesized on different substrates from a single target of h-YMnO{sub 3}. It is observed that the phase stability and crystallinity of YMO thin films depend on the substrate used and oxygen partial pressure (OPP). (110) oriented and polycrystalline growth of h-YMnO{sub 3} are observed on the Al{sub 2}O{sub 3} (0001) and NGO (110) substrates respectively, when grown in OPP {approx_equal} 10{sup -6} Torr. While for similar OPP value, growth of mixed phases (h-YMnO{sub 3} and o-YMn{sub 2}O{sub 5}) is observed on Si (001) substrate. Oriented growth of O-YMn{sub 2}O{sub 5} phase film on Si (001) substrate is observed first time, when deposited at OPP value of 225 and 350 mTorr. +3 and mixed oxidation states (+3 and +4) of Mn were confirmed by x-ray photoelectron spectroscopy in pure YMnO{sub 3} phase and YMn{sub 2}O{sub 5} phase respectively.

Kumar, Manish; Choudhary, R. J.; Phase, D. M. [UGC-DAE Consortium for Scientific Research, Khandwa Road, Indore, 452001 (India)

2012-06-05

124

Bridgman growth of large-aperture yttrium calcium oxyborate crystal  

SciTech Connect

Highlights: ? YCOB is a novel non-linear optical crystal possessing good thermal, mechanical and nonlinear optical properties. ? Large size crystal growth is key technology question for YCOB crystal. ? YCOB crystals 3 in. in diameter were grown with modified vertical Bridgman method. ? It is a more effective growth method to obtain large size and high quality YCOB crystal. -- Abstract: Large-aperture yttrium calcium oxyborate YCa{sub 4}O(BO{sub 3}){sub 3} (YCOB) crystals with 3 in. in diameter were grown with modified vertical Bridgman method, and the large crystal plate (63 mm × 68 mm × 20 mm) was harvested for high-average power frequency conversion system. The crack, facet growth and spiral growth can be effectively controlled in the as-grown crystal, and Bridgman method displays more effective in obtain large size and high quality YCOB crystal plate than Czochralski technique.

Wu, Anhua, E-mail: wuanhua@mail.sic.ac.cn [Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050 (China)] [Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050 (China); Jiang, Linwen; Qian, Guoxing; Zheng, Yanqing; Xu, Jun; Shi, Erwei [Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050 (China)] [Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050 (China)

2012-09-15

125

Novel light emissive yttrium-based nanoparticles and composites  

NASA Astrophysics Data System (ADS)

Yttrium-based inorganic optical materials generally are of practical interest for three applications: solid state lighting/displays, lasers, and scintillators. Solid-state lighting is particularly desirable commercially for its efficiency and lifetime compared to traditional incandescent alternatives. This type of lighting technology is of increasing interest as incandescent light bulbs are being gradually phased-out due to government regulations on maximum wattage of these devices. Additionally, shortcomings in the current state of the art have driven the need for a more thermally stable material for use in this area. In this dissertation, we develop and characterize a novel composite material consisting of optically active yttrium-based nanoparticles doped into silica sol-gels. For lighting and display applications, low-cost, low-temperature synthesis methods for materials that meet or exceed the quality of the materials currently on the market are highly desirable. During the course of this work, we discuss the characterization of yttrium-based nanoparticles with respect to their incorporation in a sol-gel matrix composite. We then prepared these composite materials using a variety of methods and assess their quality according to a set of selection criteria and for lighting/display applications. Novel light-emitting composites consisting of Ce:YAG or Eu:Y2O 3 (yttria) nanoparticles in an inorganic medium were successfully developed and characterized. The optical properties of the nanoparticles were maintained when incorporated into the sol-gel medium and were shown to be comparable with the current state of the art. Comparison was made between the nanoparticle emission and the composite emission and, in the case of the Ce:YAG, the CIE coordinates, showing no change between the emission intensities or peak locations. We successfully demonstrated the conversion of fluoride-based particles into Y2O3 during sol-gel processing and demonstrated that no reaction took place between the nanoparticles and the sol-gel medium. Stability of nanoparticles in suspension was overcome through the control of pH during sol-gel synthesis. Through both base- and/or acid-catalysis, we produced optically active nanoparticle doped sol-gel composites containing YAG and Yttria. Our results indicated no detrimental effect on the nanoparticles upon incorporation into the sol-gel matrix; this was demonstrated through XRD, where no silicate phases were observed, through EDX, where we saw no diffusion of yttrium into the sol-gel and no silicon diffusing into the nanoparticles, and through photoluminescence, where emissions were consistent with that of the as-made nanoparticles. These results led us to theorize that the nanoparticles, rather than being bonded to the matrix, are seated in the void space that is prevalent in sol-gel systems. Additionally, these materials are stable at much higher temperatures than current resin-based systems.

Hill, Laura Burka

126

Ferromagnetic resonance of sputtered yttrium iron garnet nanometer films  

NASA Astrophysics Data System (ADS)

Growth of nm-thick yttrium iron garnet (YIG) films by sputtering and ferromagnetic resonance (FMR) properties in the films were studied. The FMR linewidth of the YIG film decreased as the film thickness was increased from several nanometers to about 100 nm. For films with very smooth surfaces, the linewidth increased linearly with frequency. In contrast, for films with big grains on the surface, the linewidth-frequency response was strongly nonlinear. Films in the 7-26 nm thickness range showed a surface roughness between 0.1 nm and 0.4 nm, a 9.48-GHz FMR linewidth in the 6-10 Oe range, and a damping constant of about 0.001.

Liu, Tao; Chang, Houchen; Vlaminck, Vincent; Sun, Yiyan; Kabatek, Michael; Hoffmann, Axel; Deng, Longjiang; Wu, Mingzhong

2014-05-01

127

Sol-gel synthesis and characterization of yttrium gallium garnets  

NASA Astrophysics Data System (ADS)

Precursor powders for yttrium gallium garnet (Y3Ga5O12, YGG) were prepared by a simple sol-gel method based on the formation of metal chelates in aqueous solvents. A systematic study of sol-gel technique synthesized YGG samples is presented using different complexing agents. Six high-purity organic substances were used as complexing agents, namely, tartaric acid, 1,2-ethanediol, citric acid, ethylene diamine tetra-acetic acid (EDTA), malonic acid, and oxalic acid. These agents were found to influence the characteristics of the end products, in particular their homogeneity. The phase purity, composition, and microstructure of the polycrystalline samples were studied by thermoanalytical methods (TGADTA), x-ray diffraction (XRD) analysis, IR spectroscopy, and scanning electron microscopy (SEM). From the typical XRD patterns of different synthesis products it is concluded that only the use tartaric acid, 1,2-ethanediol, citric acid, and EDTA yields a single YGG phase.

Leleckaite, Asta; Urbonaite, Sigita; Tõnsuaadu, Kaia; Kareiva, Aivaras

2005-08-01

128

0145-6008/88/1201-01 19%2.00/0 ALCOHOLISM:CLINICAL AND EXPERIMENTALRFSEARCH  

E-print Network

0145-6008/88/1201-01 19%2.00/0 ALCOHOLISM:CLINICAL AND EXPERIMENTALRFSEARCH Vol. 12,No. 1 January/February 1988 Motor Performance in Detoxified Alcoholics James L. York, PhD and Irving was increasedmoreinalcoholics as target separation decreased. Female alcoholics displayed im- pairment in speed of movement

Biederman, Irving

129

Antibacterial and antibiofilm properties of yttrium fluoride nanoparticles  

PubMed Central

Antibiotic resistance has prompted the search for new agents that can inhibit bacterial growth. Moreover, colonization of abiotic surfaces by microorganisms and the formation of biofilms is a major cause of infections associated with medical implants, resulting in prolonged hospitalization periods and patient mortality. In this study we describe a water-based synthesis of yttrium fluoride (YF3) nanoparticles (NPs) using sonochemistry. The sonochemical irradiation of an aqueous solution of yttrium (III) acetate tetrahydrate [Y(Ac)3 · (H2O)4], containing acidic HF as the fluorine ion source, yielded nanocrystalline needle-shaped YF3 particles. The obtained NPs were characterized by scanning electron microscopy and X-ray elemental analysis. NP crystallinity was confirmed by electron and powder X-ray diffractions. YF3 NPs showed antibacterial properties against two common bacterial pathogens (Escherichia coli and Staphylococcus aureus) at a ?g/mL range. We were also able to demonstrate that antimicrobial activity was dependent on NP size. In addition, catheters were surface modified with YF3 NPs using a one-step synthesis and coating process. The coating procedure yielded a homogeneous YF3 NP layer on the catheter, as analyzed by scanning electron microscopy and energy dispersive spectroscopy. These YF3 NP-modified catheters were investigated for their ability to restrict bacterial biofilm formation. The YF3 NP-coated catheters were able to significantly reduce bacterial colonization compared to the uncoated surface. Taken together, our results highlight the potential to further develop the concept of utilizing these metal fluoride NPs as novel antimicrobial and antibiofilm agents, taking advantage of their low solubility and providing extended protection. PMID:23152681

Lellouche, Jonathan; Friedman, Alexandra; Gedanken, Aharon; Banin, Ehud

2012-01-01

130

Prospective Study on Exclusive, Nonsurgical Strontium\\/Yttrium90 Irradiation of Pterygia  

Microsoft Academic Search

Purpose: Prospective study to evaluate consecutive treatment results and to demonstrate safety and efficacy of nonsurgical, exclusive strontium-\\/yttrium-90 ?-irradiation of nonoperated pterygia. Patients and Methods: Between November 1999 and March 2002, 20 patients with 21 primary pterygia and six patients with recurrent pterygia after former surgery were treated with exclusive strontium-\\/yttrium-90 irradiation up to a total dose of 3,600 cGy

Bojan Pajic; Andreas Pallas; Daniel Aebersold; Guenther Gruber; Richard H. Greiner

2004-01-01

131

[Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted] Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2010. All  

E-print Network

184 YTTRIUM1 [Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted] Domestic-temperature superconductors, and superalloys. The approximate distribution in 2011 by end use was as follows: ceramics, 59, per metric ton 4 730 480 480 NA 1,600 Yttrium oxide, per kilogram, 99.9% to 99.99% purity 5 10­85 10

132

(Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2010. All  

E-print Network

184 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic-temperature superconductors, and superalloys. The approximate distribution in 2010 by end use was as follows: phosphors (all 4 300 300 300 300 300 Yttrium oxide, per kilogram, 99.9% to 99.99% purity 5 10­85 10­85 10­85 10

133

(Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2008. All  

E-print Network

184 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic-element alloys, high-temperature superconductors, and superalloys. The approximate distribution in 2007 by end 326 300 300 300 300 Yttrium oxide, per kilogram, 99.0% to 99.99% purity5 22-85 10-85 10-85 10-85 10

134

(Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic Production and Use: The rare-earth element yttrium was not mined in the United States in 2009. All  

E-print Network

182 YTTRIUM1 (Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted) Domestic-temperature superconductors, and superalloys. The approximate distribution in 2008 by end use was as follows: phosphors (all 300 300 300 300 300 Yttrium oxide, per kilogram, 99.9% to 99.99% purity5 10-85 10-85 10-85 10-85 10

135

The Meteoritical Bulletin, No. 88, 2004 July  

USGS Publications Warehouse

The Meteoritical Bulletin No. 88 lists information for 1610 newly classified meteorites, comprising 753 from Antarctica, 302 from Africa, 505 from Asia (495 of which are from Oman), 40 from North America, 5 from South America, 4 from Europe, and 1 of unknown origin. Information is provided for 9 falls (Alby sur Che??ran, Al Zarnkh, Devgaon, Kamioka, Kendrapara, Maromandia, New Orleans, Sivas, and Villalbeto de la Pen??a). Noteworthy specimens include a eucrite fall (Alby sur Che??ran), 6 martian meteorites, 13 lunar meteorites, and 12 irons including one weighing 3 metric ions (Dronino). ?? Meteoritical Society, 2004.

Russell, S.S.; Folco, L.; Grady, M.M.; Zolensky, M.E.; Jones, R.; Righter, K.; Zipfel, J.; Grossman, J.N.

2004-01-01

136

MyD88 provides a protective role in long-term radiation-induced lung injury  

PubMed Central

Purpose The role of innate immune regulators is investigated in injury sustained from irradiation as in the clinic for cancer treatment or from a nuclear incident. The protective benefits of flagellin signaling through Toll-like receptors (TLR) in an irradiation setting warrant study of a key intracellular adaptor of TLR signaling, namely Myeloid differentiation primary response factor 88 (MyD88). The role of MyD88 in regulating innate immunity and Nuclear factor kappa-B (NF-?B)-activated responses targets this critical factor for influencing injury and recovery as well as maintaining immune homeostasis. Materials and methods To examine the role of MyD88, we examined immune cells and factors during acute pneumonitic and fibrotic phases in Myd88 -deficient animals receiving thoracic gamma (?)-irradiation. Results We found that MyD88 supports survival from radiation-induced injury through the regulation of inflammatory factors that aid in recovery from irradiation. The absence of MyD88 resulted in unresolved pulmonary infiltrate and enhanced collagen deposition plus elevated type 2 helper T cell (Th2) cytokines in long-term survivors of irradiation. Conclusions These results based only on a gene deletion model suggest that alterations of MyD88-dependent inflammatory processes impact chronic lung injury. Therefore, MyD88 may contribute to attenuating long-term radiation-induced lung injury and protecting against fibrosis. PMID:22248128

Brickey, Willie J.; Neuringer, Isabel P.; Walton, William; Hua, Xiaoyang; Wang, Ellis Y.; Jha, Sushmita; Sempowski, Gregory D.; Yang, Xuebin; Kirby, Suzanne L.; Tilley, Stephen L.; Ting, Jenny P-Y.

2013-01-01

137

Bacterial infections in Myd88-deficient mice.  

PubMed

Three breeding colonies of Myd88(-/-) mice had a history of significant morbidity and mortality. Although strain-specific poor reproductive performance might explain neonatal death and dystocia, mice were found dead or required euthanasia because of moribundity, distended abdomen, head tilt, and seizures. Histopathology results included bacteremia, placentitis, metritis, peritonitis with abscess formation, and suppurative meningoencephalitis. Intralesional gram-negative coccobacilli were present, often in extremely high number. Cultures of samples of the cardiac blood of a mouse and from water-bottle sipper tubes provided to some affected mice grew Pseudomonas aeruginosa. In addition, affected tissues from 2 mice and feces from a third tested PCR-positive for P. aeruginosa. Although the mice had received autoclaved reverse-osmosis-purified drinking water, we suspect that the mice were inoculated with P. aeruginosa through contaminated sipper tubes. Because of the deficiency in most of the Toll-like receptor signaling pathways, these Myd88(-/-) mice were unlikely to have developed competitive innate and adaptive immune responses, resulting in bacterial infections. These clinical cases underscore the importance of understanding how genotype, phenotype and environment affect animal health. Sound husbandry and experimental practices are needed to prevent the exposure of immuno-deficient mice to pathogens. PMID:24674585

Villano, Jason S; Rong, Fang; Cooper, Timothy K

2014-04-01

138

Bacterial Infections in Myd88-Deficient Mice  

PubMed Central

Three breeding colonies of Myd88?/? mice had a history of significant morbidity and mortality. Although strain-specific poor reproductive performance might explain neonatal death and dystocia, mice were found dead or required euthanasia because of moribundity, distended abdomen, head tilt, and seizures. Histopathology results included bacteremia, placentitis, metritis, peritonitis with abscess formation, and suppurative meningoencephalitis. Intralesional gram-negative coccobacilli were present, often in extremely high number. Cultures of samples of the cardiac blood of a mouse and from water-bottle sipper tubes provided to some affected mice grew Pseudomonas aeruginosa. In addition, affected tissues from 2 mice and feces from a third tested PCR-positive for P. aeruginosa. Although the mice had received autoclaved reverse-osmosis–purified drinking water, we suspect that the mice were inoculated with P. aeruginosa through contaminated sipper tubes. Because of the deficiency in most of the Toll-like receptor signaling pathways, these Myd88?/? mice were unlikely to have developed competitive innate and adaptive immune responses, resulting in bacterial infections. These clinical cases underscore the importance of understanding how genotype, phenotype and environment affect animal health. Sound husbandry and experimental practices are needed to prevent the exposure of immunodeficient mice to pathogens. PMID:24674585

Villano, Jason S; Rong, Fang; Cooper, Timothy K

2014-01-01

139

Biodistribution of Yttrium-90-Labeled Anti-CD45 Antibody in a Nonhuman Primate Model  

SciTech Connect

Radioimmunotherapy may improve the outcome of hematopoietic cell transplantation for hematologic malignancies by delivering targeted radiation to hematopoietic organs while relatively sparing nontarget organs. We evaluated the organ localization of yttrium-90-labeled anti-CD45 (90Y-anti-CD45) antibody in macaques, a model that had previously predicted iodine-131-labeled anti-CD-45 (131I-anti-CD45) antibody biodistribution in humans. Experimental Design: Twelve Macaca nemestrina primates received anti-CD45 antibody labeled with 1 to 2 mCi of 90Y followed by serial blood sampling and marrow and lymph node biopsies, and necropsy. The content of 90Y per gram of tissue was determined by liquid scintillation spectrometry. Time-activity curves were constructed using average isotope concentrations in each tissue at measured time points to yield the fractional residence time and estimate radiation absorbed doses for each organ per unit of administered activity. The biodistribution of 90Y-anti-CD45 antibody was then compared with that previously obtained with 131I-anti-CD45 antibody in macaques. Results: The spleen received 2,120, marrow 1,060, and lymph nodes 315 cGy/mCi of 90Y injected. The liver and lungs were the nontarget organs receiving the highest radiation absorbed doses (440 and 285 cGy/mCi, respectively). Ytrrium-90-labeled anti-CD45 antibody delivered 2.5- and 3.7-fold more radiation to marrow than to liver and lungs, respectively. The ratios previously observed with 131I-antiCD45 antibody were 2.5-and 2.2-fold more radiation to marrow than to liver and lungs, respectively. Conclusions: This study shows that 90Y-anti-CD45 antibody can deliver relatively selective radiation to hematopoietic tissues, with similar ratios of radiation delivered to target versus nontarget organs, as compared with the 131I immunoconjugate in the same animal model.

Nemecek, Eneida; Hamlin, Donald K.; Fisher, Darrell R.; Krohn, Kenneth A.; Pagel, John M.; Applebaum, F. R.; Press, Oliver W.; Matthews, Dana C.

2005-01-15

140

Selective liquid chromatographic separation of yttrium from heavier rare earth elements using acetic acid as a novel eluent.  

PubMed

One of the major difficulties in the rare earth elements separation is purification of yttrium from heavy rare earth elements. Thus, an HPLC method using acetic acid as novel eluent was explored for selective separation of yttrium form the heavy rare earth elements. When acetic acid is used as a mobile phase yttrium eluted with the lighter lanthanides. This is contrary to its relative position amongst heavier lanthanides when eluents commonly used for separation of rare earth elements were employed. The shift in elution position of yttrium with acetic acid as eluent may reflect a relatively lower stability constant of the yttrium-AcOH complex (in the same order as for the lighter lanthanides) compared to the corresponding AcOH complexes with heavy lanthanides, enabling selective separation of yttrium from the latter. The method was successfully used for selective separation of yttrium in mixed rare earth sample containing about 80% of yttrium and about 20% of heavy rare earth oxides. Thus, the use of AcOH as eluent is an effective approach for separating and determining the trace amounts of heavy rare earth elements in large amounts of yttrium matrix. Separation was performed on C18 column by running appropriate elution programs. The effluent from the column was monitored with diode array detector at absorbance wavelength of 658nm after post column derivatization with Arsenazo III. PMID:23932372

Kifle, Dejene; Wibetoe, Grethe

2013-09-13

141

STS-88 crew members and technicians participate in their CEIT in the SSPF  

NASA Technical Reports Server (NTRS)

STS-88 crew members and Boeing Manufacturing Engineer Harry Feinberg enjoy a moment inside Node 1 of the International Space Station (ISS) during the mission's Crew Equipment Interface Test (CEIT) in KSC's Space Station Processing Facility. Discussing the mission are, from left to right, Feinberg, Commander Bob Cabana, Mission Specialist Nancy Currie, and Pilot Rick Sturckow. The CEIT gives astronauts an opportunity to get a hands-on look at the payloads with which they will be working on-orbit. STS-88, the first ISS assembly flight, is targeted for launch in July 1998 aboard Space Shuttle Endeavour.

1997-01-01

142

21 CFR 520.88e - Amoxicillin trihydrate boluses.  

Code of Federal Regulations, 2010 CFR

... 2010-04-01 false Amoxicillin trihydrate boluses. 520.88e ...ANIMAL DRUGS § 520.88e Amoxicillin trihydrate boluses. (a) Specifications...equivalent of 400 milligrams of amoxicillin. (b) Sponsor....

2010-04-01

143

21 CFR 520.88f - Amoxicillin trihydrate tablets.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Amoxicillin trihydrate tablets. 520.88f ...ANIMAL DRUGS § 520.88f Amoxicillin trihydrate tablets. (a) Specifications... Each tablet contains amoxicillin trihydrate equivalent to 50,...

2010-04-01

144

21 CFR 520.88 - Amoxicillin oral dosage forms.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Amoxicillin oral dosage forms. 520.88 ...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.88 Amoxicillin oral dosage...

2010-04-01

145

21 CFR 520.88 - Amoxicillin oral dosage forms.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 false Amoxicillin oral dosage forms. 520.88 ...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.88 Amoxicillin oral dosage...

2011-04-01

146

7 CFR 3201.88 - Agricultural spray adjuvants.  

Code of Federal Regulations, 2013 CFR

...false Agricultural spray adjuvants. 3201.88 Section 3201...88 Agricultural spray adjuvants. (a) Definition. ...in the spray tank with the herbicide, pesticide, or fertilizer...biobased agricultural spray adjuvants. By that date,...

2013-01-01

147

7 CFR 3201.88 - Agricultural spray adjuvants.  

...false Agricultural spray adjuvants. 3201.88 Section 3201...88 Agricultural spray adjuvants. (a) Definition. ...in the spray tank with the herbicide, pesticide, or fertilizer...biobased agricultural spray adjuvants. By that date,...

2014-01-01

148

28 CFR 2.88 - Confidentiality of parole records.  

... 2.88 Section 2.88 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS District of Columbia Code: Prisoners and Parolees §...

2014-07-01

149

40 CFR 725.88 - Uses of a microorganism.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 false Uses of a microorganism. 725.88 Section 725...REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Confidentiality and Public...Information § 725.88 Uses of a microorganism. (a) Assertion of...

2010-07-01

150

40 CFR 725.88 - Uses of a microorganism.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 false Uses of a microorganism. 725.88 Section 725...REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Confidentiality and Public...Information § 725.88 Uses of a microorganism. (a) Assertion of...

2013-07-01

151

40 CFR 725.88 - Uses of a microorganism.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 false Uses of a microorganism. 725.88 Section 725...REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Confidentiality and Public...Information § 725.88 Uses of a microorganism. (a) Assertion of...

2011-07-01

152

40 CFR 725.88 - Uses of a microorganism.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 false Uses of a microorganism. 725.88 Section 725...REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Confidentiality and Public...Information § 725.88 Uses of a microorganism. (a) Assertion of...

2012-07-01

153

Comparative physical and pharmacologic characteristics of iodine-131 and yttrium-90: implications for radioimmunotherapy for patients with non-Hodgkin's lymphoma.  

PubMed

Radioimmunotherapy (RIT) is a promising new treatment option for patients with relapsed/refractory non-Hodgkin's lymphoma. Clinical trials have demonstrated that both iodine-131 (131I) and yttrium-90 (90Y) are suitable radionuclides for RIT. Iodine-131 and 90Y differ markedly in their physical properties including half-life, path length, type of energy emissions, intracellular stability, and the organs targeted by the free radionuclide. Both radionuclides can be safely administered in the outpatient setting under current Nuclear Regulatory Commission guidelines. Potential advantages of 131I for RIT include availability, stable chemistry, longer half-life, and an emission spectrum that allows for dosimetric studies and therapy with the same immunoconjugate. By contrast, 90Y has a longer path length and superior intracellular stability compared with 131I. Yttrium-90 may therefore be preferable to 131I for patients with bulky disease, poorly vascularized solid tumors, or when targeting internalized antigens. Although 90Y emits no gamma photon, dosimetry studies for 90Y RIT can be performed using a surrogate radionuclide such as indium-111. Both 131I- and 90Y-labeled anti-CD20 antibodies have demonstrated efficacy in treating relapsed/refractory non-Hodgkin's lymphoma. Further studies are needed, however, to determine if the differences in the pharmacology of 131I and 90Y are clinically relevant. PMID:12743990

Leonard, John P; Siegel, Jeffry A; Goldsmith, Stanley J

2003-04-01

154

33 CFR 88.15 - Lights on dredge pipelines.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Lights on dredge pipelines. 88.15 Section 88.15 Navigation...RULES ANNEX V: PILOT RULES § 88.15 Lights on dredge pipelines. Dredge pipelines that are floating or supported on...

2011-07-01

155

33 CFR 88.15 - Lights on dredge pipelines.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Lights on dredge pipelines. 88.15 Section 88.15 Navigation...RULES ANNEX V: PILOT RULES § 88.15 Lights on dredge pipelines. Dredge pipelines that are floating or supported on...

2012-07-01

156

33 CFR 88.15 - Lights on dredge pipelines.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Lights on dredge pipelines. 88.15 Section 88.15 Navigation...RULES ANNEX V: PILOT RULES § 88.15 Lights on dredge pipelines. Dredge pipelines that are floating or supported on...

2010-07-01

157

33 CFR 88.15 - Lights on dredge pipelines.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Lights on dredge pipelines. 88.15 Section 88.15 Navigation...RULES ANNEX V: PILOT RULES § 88.15 Lights on dredge pipelines. Dredge pipelines that are floating or supported on...

2013-07-01

158

36 CFR 7.88 - Indiana Dunes National Lakeshore.  

Code of Federal Regulations, 2012 CFR

...Public Property 1 2012-07-01 2012-07-01 false Indiana Dunes National Lakeshore. 7.88 Section 7.88 Parks...REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.88 Indiana Dunes National Lakeshore. (a) Fishing. Unless...

2012-07-01

159

36 CFR 7.88 - Indiana Dunes National Lakeshore.  

Code of Federal Regulations, 2010 CFR

...Public Property 1 2010-07-01 2010-07-01 false Indiana Dunes National Lakeshore. 7.88 Section 7.88 Parks...REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.88 Indiana Dunes National Lakeshore. (a) Fishing. Unless...

2010-07-01

160

36 CFR 7.88 - Indiana Dunes National Lakeshore.  

Code of Federal Regulations, 2011 CFR

...Public Property 1 2011-07-01 2011-07-01 false Indiana Dunes National Lakeshore. 7.88 Section 7.88 Parks...REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.88 Indiana Dunes National Lakeshore. (a) Fishing. Unless...

2011-07-01

161

36 CFR 7.88 - Indiana Dunes National Lakeshore.  

Code of Federal Regulations, 2013 CFR

...Public Property 1 2013-07-01 2013-07-01 false Indiana Dunes National Lakeshore. 7.88 Section 7.88 Parks...REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.88 Indiana Dunes National Lakeshore. (a) Fishing. Unless...

2013-07-01

162

MASKER MASKER TARGET TARGET TARGET  

E-print Network

from a large speech database (Ives et al,2005). The original speech is from one speaker Probabilitycorrect -6 dB 0 dB Listeners were presented with two phrases of concurrent speech syllables. The masker syllables coincided with the second and third target syllables. The speech syllables were taken

Ives, D. Timothy

163

Low-voltage cathodoluminescence of europium-activated yttrium orthovanadate  

SciTech Connect

Emissive flat panel display systems operating in full color demand higher performance at low voltages (ca. 501000 V) from cathodoluminescent (CL) phosphors than cathode ray tubes require. Hydrothermal synthesis has been suggested as a route to phosphors with improved efficiencies, lower voltage thresholds, and increased saturation power. This hypothesis was tested in europium-doped yttrium orthovanadate (YVO{sub 4}:Eu), an efficient, red emitting CL phosphor. The CL efficiency of YVO{sub 4}:Eu crystallized from aqueous solution at 200{degrees}C is relatively low until it is annealed. The distribution of particle sizes in the low-temperature phosphor is similar to that in material made via a solid-state route, but crystallites remain much smaller (ca. 400 {Angstrom}) until they are annealed. These observations, along with the anomalously strong dependence of CL intensity on europium concentration, support a model in which efficiency principally depends on crystallite size. CL efficiency of both solid state and hydrothermal YVO{sub 4}:Eu increases with voltage at constant power. Surface-bound electrons are likely the dominant influence on efficiency at voltages near threshold. Saturation power is independent of synthetic route. It is apparent that the CL properties of hydrothermally synthesized YVO{sub 4}:Eu are essentially the same as those of YVO{sub 4}:Eu produced via conventional, high-temperature routes.

Phillips, M.L.F.

1995-03-01

164

Magnon thermal mean free path in yttrium iron garnet  

NASA Astrophysics Data System (ADS)

The magnetothermal properties of monocrystalline yttrium iron garnet (YIG) are reported. The magnon contribution to both the thermal conductivity and specific heat at low temperatures has been determined by measuring these properties under an applied magnetic field, which allows us to freeze the magnon modes and isolate the phonon contribution relative to the zero-field behavior. These results are interpreted within the framework of a simple kinetic gas model for magnon heat conduction that allows us to estimate the magnon thermal mean free path, i.e., the inelastic scattering length scale for thermally driven bulk magnons. We observe this parameter to reach as high as approximately 100 ?m at 2 K. It tracks the acoustic phonon thermal mean free path closely and decreases rapidly as the temperature is increased. This relatively short length scale suggests that magnon modes at thermal energies in YIG are not solely or directly responsible for coherent macroscale thermal spin transport (e.g., in the spin Seebeck effect) at high temperatures. Instead, these results support a growing consensus that subthermal magnons, i.e., those at energies below about 30 ± 10 K, are important for spin transport in YIG at all temperatures. These results also emphasize that magnon effects should be considered wavelength dependent, and that magnon-magnon interactions may be just as important for thermal spin transport as magnon-phonon scattering. This, in turn, has implications for understanding the characteristic temperature and length scales involved in spin caloritronic phenomena.

Boona, Stephen R.; Heremans, Joseph P.

2014-08-01

165

Few-MeV neutrons incident on yttrium  

SciTech Connect

Neutron total and scattering cross sections of elemental yttrium are measured in the few-MeV region with broad resolutions. The total-cross section measurements extend from approx. = 0.5 to 4.2 MeV in steps of less than or equal to 0.1 MeV. Neutron elastic- and inelastic-scattering cross sections are measured from approx. = 1.5 to 4.0 MeV, at incident-neutron energy intervals of less than or equal to 50 keV and at ten or more scattering angles distributed between 20 and 160 deg. Inelastically-scattered neutron groups are observed corresponding to the excitation of levels at 909 +- 23, 1504 +- 20, 1747 +- 16, 2224 +- 16, 2567 +- 26, 2889 +- 12 and 3104 +- 10 keV. The experimental results are discussed in terms of the spherical optical-statistical, coupled-channels and core-coupling models and compared with corresponding quantities given in the evaluated nuclear data file ENDF/B-V.

Budtz-Jorgensen, C.; Guenther, P.; Smith, A.; Whalen, J.

1982-09-01

166

Phase Diagram for Magnon Condensate in Yttrium Iron Garnet Film  

PubMed Central

Recently, magnons, which are quasiparticles describing the collective motion of spins, were found to undergo Bose-Einstein condensation (BEC) at room temperature in films of Yttrium Iron Garnet (YIG). Unlike other quasiparticle BEC systems, this system has a spectrum with two degenerate minima, which makes it possible for the system to have two condensates in momentum space. Recent Brillouin Light Scattering studies for a microwave-pumped YIG film of thickness d = 5??m and field H = 1?kOe find a low-contrast interference pattern at the characteristic wavevector Q of the magnon energy minimum. In this report, we show that this modulation pattern can be quantitatively explained as due to unequal but coherent Bose-Einstein condensation of magnons into the two energy minima. Our theory predicts a transition from a high-contrast symmetric state to a low-contrast non-symmetric state on varying the d and H, and a new type of collective oscillation. PMID:23455849

Li, Fuxiang; Saslow, Wayne M.; Pokrovsky, Valery L.

2013-01-01

167

Nanoscale inhomogeneities in yttrium-barium-copper-oxide (YBCO) superconductors  

NASA Astrophysics Data System (ADS)

X-ray diffraction studies at the Advanced Photon Source reveal that nanoscale inhomogeneities, electronic or structural in origin, form in yttrium-barium-copper-oxide (YBa_2Cu_3O_6+x) superconductors and coexist with the superconducting (SC) state. Diffuse scattering from these inhomogeneous superstructures is due to atomic displacements with respect to equilibrium lattice sites (Z. Islam et al. Phys. Rev. B 66, 92501 (2002)), that are characterized by a wavevector of the form q=(q_x,0,0), where qx varies with hole doping from 2 unit cells (along shorter Cu-O-Cu direction) for very low doping to 4 unit cells at optimal doping. Interestingly, while these superstructures are 3-dimensionally ordered when the SC state is weakened (e.g., at x=0.4), as the doping increases, they become quasi 1D with correlation lengths comparable to SC coherence lengths in these cuprates. Recent first-principles calculations (D. de Fontaine et al., to be published) for the x=0.63 compound show that atomic displacements consistent with experimental data can be the result of ordering of O vacancies in YBCO. Models for various superstructures and their role in the phase diagram will be discussed.

Islam, Zahirul; Sinha, S. K.; Lang, J. C.; Liu, X.; Haskel, D.; Moss, S. C.; Srajer, G.; Veal, B. W.; Wermeille, D.; Lee, D. R.; Haeffner, D. R.; Welp, U.; Wochner, P.

2004-03-01

168

Trans-arterial hepatic radioembolisation of yttrium-90 microspheres  

PubMed Central

The liver represents a frequent site for metastatic disease, in addition to being a site for primary cancer. Hepatic metastases from certain neoplasms, such as colon, neuroendocrine, melanoma and gastrointestinal stromal tumour have a distinct predilection to metastasize the liver, which in many cases may represent the only or the dominant site of disease. In these circumstances, cytoreduction via surgery or in situ ablative techniques aims to influence the natural history of the disease progression and improve clinical outcomes. Liver directed therapy utilising yttrium-90 microspheres represents a recently introduced in situ multidisciplinary cancer therapy that has caught the attention of many physicians faced with the challenges of treating these complex patients. Although similar to other forms of trans-arterial liver directed therapy, there are discrete differences and potentially fatal treatment consequences unique to this therapy. This objective of this review article is to provide the reader a basis for understanding the therapeutic principles, patient exclusion criteria, pre and post therapy investigations and salient clinical results in the two most commonly treated disease types; metastatic colorectal cancer and hepatocellular cancer. PMID:21614250

Murthy, R; Habbu, A; Salem, R

2006-01-01

169

Structural and electrical properties of zirconium doped yttrium oxide nanostructures  

NASA Astrophysics Data System (ADS)

A synthetic process for the formation of ZrxY1-xOy nanostructures is demonstrated by the reaction of yttrium nitrate hexahydrate with zirconium propoxide. The reactions are carried out at temperature 60°C and pressure 0.1 MPa. The energy dispersive X-ray (EDX) spectroscopy measurements confirm formation of ZrxY1-xOy nanostructures and the presence of carbonate and hydroxide species which are removed after high temperature anneals. It was found that the oxygen pressure during synthesis plays a determinant role on the structural properties of the nanostructure. This effect is further studied by atomic force microscopy (AFM) measurements and scanning electron microscope (SEM), which showed the formation of an isotopically organized structure. X-ray diffraction (XRD) measurement reveals that these changes in the nanostructural efficiency are associated with structural and compositional changes among the substrate. The dielectric constant as measured by the capacitance-voltage (C-V) technique is estimated to be around 39.05. C-V measurements taken at 1 MHz show the maximum capacitance for the Zr0.05Y0.95Oy film. The leakage current densities were below 10-5 A/cm2 for the Zr0.05Y0.95Oy film.

Bahari, Ali; Ebrahimzadeh, Masoud; Gholipur, Reza

2014-04-01

170

Phase diagram for magnon condensate in Yttrium Iron Garnet film.  

PubMed

Recently, magnons, which are quasiparticles describing the collective motion of spins, were found to undergo Bose-Einstein condensation (BEC) at room temperature in films of Yttrium Iron Garnet (YIG). Unlike other quasiparticle BEC systems, this system has a spectrum with two degenerate minima, which makes it possible for the system to have two condensates in momentum space. Recent Brillouin Light Scattering studies for a microwave-pumped YIG film of thickness d = 5??m and field H = 1?kOe find a low-contrast interference pattern at the characteristic wavevector Q of the magnon energy minimum. In this report, we show that this modulation pattern can be quantitatively explained as due to unequal but coherent Bose-Einstein condensation of magnons into the two energy minima. Our theory predicts a transition from a high-contrast symmetric state to a low-contrast non-symmetric state on varying the d and H, and a new type of collective oscillation. PMID:23455849

Li, Fuxiang; Saslow, Wayne M; Pokrovsky, Valery L

2013-01-01

171

Method of forming a relatively stable slip of silicon metal particles and yttrium containing particles  

SciTech Connect

The method concerns forming a relatively stable slip of silicon metal particles and yttrium containing particles. In one embodiment, a casting slip of silicon metal particles is formed in water. Particles of a yttrium containing sintering aid are added to the casting slip. The yttrium containing sintering aid is a compound which has at least some solubility in water to form Y/sup +3/ ions which have a high potential for totally flocculating the silicon metal particles into a semiporous solid. A small amount of a fluoride salt is added to the casting slip which contains the yttrium containing sintering aid. The fluoride salt is one which will produce fluoride anions when dissolved in water. The small amount of the fluoride anions produced are effective to suppress the flocculation of the silicon metal particles by the Y/sup +3/ ions so that all particles remain in suspension in the casting slip and the casting slip has both an increased shelf life and can be used to cast articles having a relatively thick crosssection. The pH of the casting slip is maintained in a range from 7.5 to 9. Preferably, the fluoride salt used is one which is based on a monovalent cation such as sodium or ammonia. The steps of adding the yttrium containing sintering aid and the fluoride salt may be interchanged if desired, and the salt may be added to a solution containing the sintering aid prior to addition of the silicon metal particles.

Dickie, R.A.; Mangels, J.A.

1984-09-11

172

Yttrium-doped cobalt nanoferrites prepared by sol-gel combustion method and its characterization.  

PubMed

Ferrites are extremely important magnetic ceramics in the production of electronic components because they reduce the energy losses by the induced currents acting as electrical insulators. Similarly, the spinel-structured cobalt-based ferrites are promising materials for stress, torsion sensors and energy storage applications (anode materials in lithium batteries, fuel cells and solar cells). Therefore, many studies have focused on cobalt ferrites obtained using conventional techniques. Different sintering conditions, types and levels of substitution result in different microstructures and magnetostriction coefficients under a wide range of preparation conditions. Despite many attempts, there are no specific reports on the trivalent substitution of yttrium in cobalt ferrite to the best of our knowledge. In the present study, yttrium-doped cobalt ferrite was prepared with different concentrations to identify the crystallite size with respect to the yttrium concentration, temperature and changes in the structural and electrical properties. In addition, the resistance of the nanostructured yttrium-doped cobalt ferrites nanopowders was analyzed. The resistance was increased by the addition of yttrium to cobalt ferrites. PMID:23858896

Shobana, M K; Nam, Wonjong; Choe, Heeman

2013-05-01

173

Activation of TAK1 by MYD88 L265P drives malignant B-cell Growth in non-Hodgkin lymphoma  

PubMed Central

Massively parallel sequencing analyses have revealed a common mutation within the MYD88 gene (MYD88L265P) occurring at high frequencies in many non-Hodgkin lymphomas (NHLs) including the rare lymphoplasmacytic lymphoma, Waldenström's macroglobulinemia (WM). Using whole-exome sequencing, Sanger sequencing and allele-specific PCR, we validate the initial studies and detect the MYD88L265P mutation in the tumor genome of 97% of WM patients analyzed (n=39). Due to the high frequency of MYD88 mutation in WM and other NHL, and its known effects on malignant B-cell survival, therapeutic targeting of MYD88 signaling pathways may be clinically useful. However, we are lacking a thorough characterization of the role of intermediary signaling proteins on the biology of MYD88L265P-expressing B cells. We report here that MYD88L265P signaling is constitutively active in both WM and diffuse large B-cell lymphoma cells leading to heightened MYD88L265P, IRAK and TRAF6 oligomerization and NF-?B activation. Furthermore, we have identified the signaling protein, TAK1, to be an essential mediator of MYD88L265P-driven signaling, cellular proliferation and cytokine secretion in malignant B cells. Our studies highlight the biological significance of MYD88L265P in NHL and reveal TAK1 inhibition to be a potential therapeutic strategy for the treatment of WM and other diseases characterized by MYD88L265P. PMID:24531446

Ansell, S M; Hodge, L S; Secreto, F J; Manske, M; Braggio, E; Price-Troska, T; Ziesmer, S; Li, Y; Johnson, S H; Hart, S N; Kocher, J-P A; Vasmatzis, G; Chanan-Kahn, A; Gertz, M; Fonseca, R; Dogan, A; Cerhan, J R; Novak, A J

2014-01-01

174

TLR4 induces tumor growth and inhibits paclitaxel activity in MyD88-positive human ovarian carcinoma in vitro  

PubMed Central

In ovarian cancer patients, chemotherapy resistance is the principal factor restricting long-term treatment. Paclitaxel (Pac) has been previously reported to be a ligand to Toll-like receptor 4 (TLR4). It was determined that TLR4 signaling is divided into the following two pathways: Myeloid differentiation factor 88 (MyD88)-dependent and MyD88-independent. The present study investigated the effect of TLR4 ligation by Pac in MyD88-positive (MyD88+) and MyD88-negative (MyD88?) human ovarian cancer cell lines. An RNA interference expression vector was specifically constructed to target TLR4 mRNA, which was stably transfected into the human ovarian cancer cell lines (SKOV3, OVCAR3, A2780 and 3AO). Cytokines, including interleukin (IL)-6 and IL-8, were detected. Cell proliferation and apoptosis were assessed in the cells transfected with scramble control and TLR4 shRNA to explore the possible functions of TLR4 in ovarian cancer cell growth. It was found that lipopolysaccharide and Pac significantly increase the secretion of IL-6 and IL-8 in the SKOV3 cell line. Similarly, Pac resulted in a significant upregulation of IL-6 and IL-8 in OVCAR3 cells, but not in A2780 and 3AO cells. These results suggested that in MyD88+ ovarian cancer cell lines, TLR4 depletion shows increased sensitivity to Pac treatment in inhibiting cell proliferation compared with in cells without TLR4 knockdown. On the contrary, such changes were not found in MyD88? cells (A2780 and 3AO). TLR4 negatively regulates Pac chemotherapy, particularly in terms of cell proliferation, and TLR4 may be a novel treatment target in Pac-resistant ovarian cancer. PMID:24527095

WANG, AN-CONG; MA, YUE-BING; WU, FENG-XIA; MA, ZHI-FANG; LIU, NAI-FU; GAO, RONG; GAO, YONG-SHENG; SHENG, XIU-GUI

2014-01-01

175

Characterisation of bismuth-doped yttrium iron garnet layers prepared by sol-gel process  

NASA Astrophysics Data System (ADS)

Yttrium iron garnets and Bi-substituted yttrium iron garnets were prepared by two different sol-gel processes. We investigated the evolution with temperature of XRD patterns and of the magnetisation of powders issued from sol-gel solution decomposition. We prepared layers on silica glass by the spin- or dip-coating processes. XRD patterns on layers were also obtained. The dependency of the Faraday effect upon the light wavelength and Bi amount was shown. The main result is the possibility to prepare stable sol-gel solutions containing bismuth, yttrium and iron precursors which lead to garnet phase after annealing at low temperature. These bismuth-doped garnet phases give the expected magneto-optical properties. These processes are promising for the preparation of inexpensive magneto-optical recording media.

Rehspringer, J.-L. J.-L.; Bursik, J.; Niznansky, D.; Klarikova, A.

2000-03-01

176

Production and quality control of radioactive yttrium microspheres for medical applications.  

PubMed

In this paper, a method for production of yttrium silicate microspheres is reported. Yttrium silicate microspheres with approximate sizes of 20-50µm were obtained when an aqueous solution of Y(NO3)3 was added to tetraethyl orthosilicate (TEOS) and was pumped into silicone oil under constant stirring. The shapes of the particles produced by the proposed method were regular and nearly spherical. The spherical shapes, composition and element distribution were investigated by scanning electron microscopy (SEM), carbon/sulfur analysis and SEM/EDS mapping analysis. Paper chromatography was used to identify radiochemical impurities in the radioactive microspheres. The radionuclide purity was determined using a gamma spectrometry system and an ultra-low-level liquid scintillation spectrometer. The results indicated that the proposed silicone oil spheroidization method is suitable for the production of yttrium silicate microspheres. PMID:24389532

Ghahramani, M R; Garibov, A A; Agayev, T N

2014-02-01

177

Yttrium segregation and surface phases of yttria-stabilized zirconia (1 1 1) surface  

NASA Astrophysics Data System (ADS)

Surface segregation of yttria-stabilized zirconia (YSZ) was studied via first-principles computations and thermodynamics. For the cubic YSZ (1 1 1) surface, yttrium can segregate only to a subsurface layer, and these segregation phases are terminated at the surface by defective oxygen layers with honeycomb structure. The segregation is independent of the bulk yttrium concentration at high oxygen partial pressures or low temperatures. At very low oxygen partial pressures and high temperatures there is no surface yttrium segregation and the surface is terminated by O-Zr. Our results provide a reasonable explanation for previous experimental work, and also a framework for extending our understanding of cation segregation in oxide surfaces.

Wang, Xiao-Gang

178

Hanford isotope project strategic business analysis yttrium-90 (Y-90)  

SciTech Connect

The purpose of this analysis is to address the short-term direction for the Hanford yttrium-90 (Y-90) project. Hanford is the sole DOE producer of Y-90, and is the largest repository for its source in this country. The production of Y-90 is part of the DOE Isotope Production and Distribution (IP and D) mission. The Y-90 is ``milked`` from strontium-90 (Sr-90), a byproduct of the previous Hanford missions. The use of Sr-90 to produce Y-90 could help reduce the amount of waste material processed and the related costs incurred by the clean-up mission, while providing medical and economic benefits. The cost of producing Y-90 is being subsidized by DOE-IP and D due to its use for research, and resultant low production level. It is possible that the sales of Y-90 could produce full cost recovery within two to three years, at two curies per week. Preliminary projections place the demand at between 20,000 and 50,000 curies per year within the next ten years, assuming FDA approval of one or more of the current therapies now in clinical trials. This level of production would incentivize private firms to commercialize the operation, and allow the government to recover some of its sunk costs. There are a number of potential barriers to the success of the Y-90 project, outside the control of the Hanford Site. The key issues include: efficacy, Food and Drug Administration (FDA) approval and medical community acceptance. There are at least three other sources for Y-90 available to the US users, but they appear to have limited resources to produce the isotope. Several companies have communicated interest in entering into agreements with Hanford for the processing and distribution of Y-90, including some of the major pharmaceutical firms in this country.

NONE

1995-10-01

179

Root Cause Analysis of Gastroduodenal Ulceration After Yttrium-90 Radioembolization  

SciTech Connect

IntroductionA root cause analysis was performed on the occurrence of gastroduodenal ulceration after hepatic radioembolization (RE). We aimed to identify the risk factors in the treated population and to determine the specific mechanism of nontarget RE in individual cases. Methods: The records of 247 consecutive patients treated with yttrium-90 RE for primary (n = 90) or metastatic (n = 157) liver cancer using either resin (n = 181) or glass (n = 66) microspheres were reviewed. All patients who developed a biopsy-proven microsphere-induced gastroduodenal ulcer were identified. Univariate and multivariate analyses were performed on baseline parameters and procedural data to determine possible risk factors in the total population. Individual cases were analyzed to ascertain the specific cause, including identification of the culprit vessel(s) leading to extrahepatic deposition of the microspheres. Results: Eight patients (3.2 %) developed a gastroduodenal ulcer. Stasis during injection was the strongest independent risk factor (p = 0.004), followed by distal origin of the gastroduodenal artery (p = 0.004), young age (p = 0.040), and proximal injection of the microspheres (p = 0.043). Prolonged administrations, pain during administration, whole liver treatment, and use of resin microspheres also showed interrelated trends in multivariate analysis. Retrospective review of intraprocedural and postprocedural imaging showed a probable or possible culprit vessel, each a tiny complex collateral vessel, in seven patients. Conclusion: Proximal administrations and those resulting in stasis of flow presented increased risk for gastroduodenal ulceration. Patients who had undergone bevacizumab therapy were at high risk for developing stasis.

Lam, Marnix G. E. H. [Stanford University School of Medicine, Division of Interventional Radiology (United States); Banerjee, Subhas [Stanford University School of Medicine, Division of Gastroenterology and Hepatology (United States)] [Stanford University School of Medicine, Division of Gastroenterology and Hepatology (United States); Louie, John D.; Abdelmaksoud, Mohamed H. K. [Stanford University School of Medicine, Division of Interventional Radiology (United States)] [Stanford University School of Medicine, Division of Interventional Radiology (United States); Iagaru, Andrei H. [Stanford University School of Medicine, Division of Nuclear Medicine and Molecular Imaging (United States)] [Stanford University School of Medicine, Division of Nuclear Medicine and Molecular Imaging (United States); Ennen, Rebecca E.; Sze, Daniel Y., E-mail: dansze@stanford.edu [Stanford University School of Medicine, Division of Interventional Radiology (United States)

2013-12-15

180

Selective encapsulation of the carbides of yttrium and titanium into carbon nanoclusters  

NASA Astrophysics Data System (ADS)

Characterization of the arc-discharge deposits at the cathode from anodes containing yttrium oxide and titanium by transmission electron microscopy and x-ray diffraction shows different results with respect to an encapsulation of the metal carbides into carbon clusters. Yttrium carbide is encapsulated into carbon nanoclusters in a crystalline phase. The formation of titanium carbide, on the other hand, preempts the formation of the carbon—carbon bonds necessary to form the carbon cages, so that only titanium carbide clusters are observed. Thermodynamic data support the interpretation of the results.

Seraphin, Supapan; Zhou, Dan; Jiao, Jun; Withers, James C.; Loutfy, Raouf

1993-10-01

181

Direct Observation and Calipering of the {open_quotes}Webbing{close_quotes} Fermi Surface of Yttrium  

SciTech Connect

The first measurement of both the size and shape of the region of the Fermi surface of yttrium known as the {open_quotes}webbing{close_quotes} is reported. This particular Fermi surface feature is of considerable interest because it is very similar to that found in a number of the heavier rare earth metals, where it is believed to play a vital role in driving the exotic magnetic structures found therein. In this positron study, two-dimensional angular correlation measurements combined with three-dimensional reconstruction provide a direct image of this part of the yttrium Fermi surface. {copyright} {ital 1997} {ital The American Physical Society}

Dugdale, S.B.; Fretwell, H.M.; Alam, M.A. [H.H.Wills Physics Laboratory, University of Bristol,Tyndall Avenue, Bristol, BS8 1TL (United Kingdom)] [H.H.Wills Physics Laboratory, University of Bristol,Tyndall Avenue, Bristol, BS8 1TL (United Kingdom); Kontrym-Sznajd, G. [Polish Academy of Sciences, W. Trzebiatowski Intsitute of Low Temperature and Structure Research, 50-950 Wroclaw 2, P.O.Box 937 (Poland)] [Polish Academy of Sciences, W. Trzebiatowski Intsitute of Low Temperature and Structure Research, 50-950 Wroclaw 2, P.O.Box 937 (Poland); West, R.N.; Badrzadeh, S. [Department of Physics, University of Texas at Arlington, P.O.Box 19059, Arlington, Texas 76019 (United States)] [Department of Physics, University of Texas at Arlington, P.O.Box 19059, Arlington, Texas 76019 (United States)

1997-08-01

182

Preparation of yttrium, lanthanum, cerium, and neodymium basic carbonate particles by homogeneous precipitation  

SciTech Connect

Uniform yttrium, lanthanum, cerium, and neodymium basic carbonate particles were prepared by homogeneous precipitation. Powders were characterized with respect to size, shape, crystal structure, and thermal decomposition behavior. Yttria precursor particles were spherical, monosized (0.4 {mu}m), and amorphous; whereas lanthana, neodymia, and ceria precursors were prismatic (ranging from 1 to 6 {mu}m in size) and crystalline. Crystal structure was found to be ancylite-type orthorhombic symmetry in all three cases. Upon heating in air, yttrium, lanthanum, and neodymium precursors underwent two-step decomposition to first form oxycarbonate and then oxide. Cerium hydroxycarbonate decomposed in a single step to form the oxide.

Akinc, M.; Sordelet, D. (Iowa State Univ., Ames (USA))

1987-07-01

183

Hydrothermal synthesis, crystal structures and photoluminescence properties of mixed europium-yttrium organic frameworks  

NASA Astrophysics Data System (ADS)

Three mixed europium-yttrium organic frameworks: Eu2-xYx(Mel)(H2O)6 (Mel=mellitic acid or benzene-1,2,3,4,5,6-hexacarboxylic acid, x=0.38 1, 0.74 2, and 0.86 3) have been synthesized and characterized. All the compounds contain a 3-D net with (4, 8)-flu topology. The study indicates that the photoluminescence properties are effectively affected by the different ratios of europium and yttrium ions, the quantum efficiency is increased and the Eu3+ lifetime becomes longer in these MOFs than those of the Eu analog.

Han, Yinfeng; Fu, Lianshe; Mafra, Luís; Shi, Fa-Nian

2012-02-01

184

Atomic layer deposition of the aluminum oxide-yttrium oxide pseudo-binary system  

Microsoft Academic Search

The growth of thin films of selected phases from the pseudo-binary Al 2O3-Y2O3 material system was demonstrated using atomic layer deposition (ALD). Specifically ALD growth of Al2O 3, Y2O3, Ce2O3, Y2 Al4O12 (Yttrium Aluminum Monoclinic - YAM), and Y3Al5O12 (Yttrium Aluminum Garnet - YAG) was accomplished. All films were grown using the same precursors: AlCl 3 at 105°C and H2O,

Jason Conrad Rowland

2009-01-01

185

[Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted] Domestic Production and Use: Rare earths were mined by one U.S. company in 2013. Bastnasite, a rare-earth  

E-print Network

182 YTTRIUM1 [Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted] Domestic-earth oxide mineral concentrate in 2013 was estimated to be 4,000 tons in 2013. Yttrium was estimated and as a deoxidizer. Yttrium was used in heating-element alloys, high-temperature superconductors, and superalloys

186

Planktic foraminifer census data from Northwind Ridge cores PI-88-AP P3, PI-88-AR P7 and PI-88-AR P9, Arctic Ocean  

USGS Publications Warehouse

The U.S. Geological Survey recovered 9 piston cores from the Northwind Ridge in the Canada Basin of the Arctic Ocean from a cruise of the USCGC Polar Star during 1988. Preliminary analysis of the cores suggests sediments deposited on Northwind Ridge preserve a detailed record of glacial and interglacial cycles for the last few hundred-thousand to one million years. This report includes quantitative data on foraminifers and selected sediment size-fraction data in 98 samples from Northwind Ridge core PI-88AR P3, 51 samples from core PI-88-AR P7 and 117 samples from core PI-88-AR P9.

Foley, Kevin M.; Poore, Richard Z.

1993-01-01

187

Preparation and anticoagulant activity of the phosphosulfomannan PI88  

Microsoft Academic Search

A yeast-derived phosphomannan mixture was chemically sulfonated and the composition and structure of the product mixture was studied. This phosphosulfomannan mixture, PI-88, is currently under clinical evaluation as an anti-cancer agent. Analysis using capillary electrophoresis demonstrated that PI-88 was a multi-component mixture. Gel permeation chromatography provided four fractions of PI-88 that contained components which differed in size from disaccharide to

Guangli Yu; Nur Sibel Gunay; Robert J Linhardt; Toshihiko Toida; Jawed Fareed; Debra A Hoppensteadt; Hazar Shadid; Vito Ferro; Caiping Li; Kym Fewings; Maria C Palermo; Denis Podger

2002-01-01

188

Rotated stripe order and its competition with superconductivity in La1.88Sr0.12CuO4  

NASA Astrophysics Data System (ADS)

We report the observation of a bulk charge modulation in La1.88Sr0.12CuO4 (LSCO) with a characteristic in-plane wave vector of (0.236,±?), with ? =0.011 r.l.u. The transverse shift of the ordering wave vector indicates the presence of rotated charge-stripe ordering, demonstrating that the charge ordering is not pinned to the Cu-O bond direction. On cooling through the superconducting transition, we find an abrupt change in the growth of the charge correlations and a suppression of the charge order parameter indicating competition between the two orderings. Orthorhombic LSCO thus helps bridge the apparent disparities between the behavior previously observed in the tetragonal "214" cuprates and the orthorhombic yttrium and bismuth-based cuprates and thus lends strong support to the idea that there is a common motif to charge order in all cuprate families.

Thampy, V.; Dean, M. P. M.; Christensen, N. B.; Steinke, L.; Islam, Z.; Oda, M.; Ido, M.; Momono, N.; Wilkins, S. B.; Hill, J. P.

2014-09-01

189

7 CFR 1214.88 - OMB control numbers.  

Code of Federal Regulations, 2012 CFR

...AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE CHRISTMAS TREE PROMOTION, RESEARCH, AND INFORMATION ORDER Christmas Tree Promotion, Research, and Information Order Miscellaneous § 1214.88 OMB...

2012-01-01

190

40 CFR 8.8 - Comprehensive environmental evaluation.  

Code of Federal Regulations, 2010 CFR

...8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL ENVIRONMENTAL IMPACT ASSESSMENT OF NONGOVERNMENTAL ACTIVITIES IN ANTARCTICA § 8.8 Comprehensive environmental evaluation. (a) Preparation...

2010-07-01

191

Structural and functional characterization of CFE88: Evidence that a conserved and essential bacterial protein is a methyltransferase  

PubMed Central

CFE88 is a conserved essential gene product from Streptococcus pneumoniae. This 227-residue protein has minimal sequence similarity to proteins of known 3Dstructure. Sequence alignment models and computational protein threading studies suggest that CFE88 is a methyltransferase. Characterization of the conformation and function of CFE88 has been performed by using several techniques. Backbone atom and limited side-chain atom NMR resonance assignments have been obtained. The data indicate that CFE88 has two domains: an N-terminal domain with 163 residues and a C-terminal domain with 64 residues. The C-terminal domain is primarily helical, while the N-terminal domain has a mixed helical/extended (Rossmann) fold. By aligning the experimentally observed elements of secondary structure, an initial unrefined model of CFE88 has been constructed based on the X-ray structure of ErmC? methyltransferase (Protein Data Bank entry 1QAN). NMR and biophysical studies demonstrate binding of S-adenosyl-L-homocysteine (SAH) to CFE88; these interactions have been localized by NMR to the predicted active site in the N-terminal domain. Mutants that target this predicted active site (H26W, E46R, and E46W) have been constructed and characterized. Overall, our results both indicate that CFE88 is a methyltransferase and further suggest that the methyltransferase activity is essential for bacterial survival. PMID:15929997

Constantine, Keith L.; Krystek, Stanley R.; Healy, Matthew D.; Doyle, Michael L.; Siemers, Nathan O.; Thanassi, Jane; Yan, Ning; Xie, Dianlin; Goldfarb, Valentina; Yanchunas, Joseph; Tao, Li; Dougherty, Brian A.; Farmer, Bennett T.

2005-01-01

192

Increased N-glycosylation of Asn88 in serum pancreatic ribonuclease 1 is a novel diagnostic marker for pancreatic cancer  

PubMed Central

Alterations of carbohydrate structures in cancer cells are the most promising targets for developing clinical diagnostic reagents. Pancreatic cancer is one of the most difficult cancers to diagnose because it lacks definitive symptoms. Two antibodies were raised against human pancreatic ribonuclease 1 that bind to the enzyme containing unglycosylated Asn88, but not when its Asn88 is N-glycosylated. Differential studies using these antibodies in immunoassays and Western blot analyses showed a significant increase in the serum levels of pancreatic ribonuclease 1 containing N-glycosylated Asn88 in pancreatic cancer patients compared with normal human subjects. Focusing on the increase in an N-glycosylated Asn residue of serum pancreatic ribonuclease 1, specifically Asn88, affords a new diagnostic marker for pancreatic cancer. This is the first report of a diagnostic cancer marker that takes advantage of the presence or absence of N-glycosylation at a specific Asn residue of a glycoprotein. PMID:25336120

Nakata, Daisuke

2014-01-01

193

Increased N-glycosylation of Asn(88) in serum pancreatic ribonuclease 1 is a novel diagnostic marker for pancreatic cancer.  

PubMed

Alterations of carbohydrate structures in cancer cells are the most promising targets for developing clinical diagnostic reagents. Pancreatic cancer is one of the most difficult cancers to diagnose because it lacks definitive symptoms. Two antibodies were raised against human pancreatic ribonuclease 1 that bind to the enzyme containing unglycosylated Asn(88), but not when its Asn(88) is N-glycosylated. Differential studies using these antibodies in immunoassays and Western blot analyses showed a significant increase in the serum levels of pancreatic ribonuclease 1 containing N-glycosylated Asn(88) in pancreatic cancer patients compared with normal human subjects. Focusing on the increase in an N-glycosylated Asn residue of serum pancreatic ribonuclease 1, specifically Asn(88), affords a new diagnostic marker for pancreatic cancer. This is the first report of a diagnostic cancer marker that takes advantage of the presence or absence of N-glycosylation at a specific Asn residue of a glycoprotein. PMID:25336120

Nakata, Daisuke

2014-01-01

194

Post-radioembolization yttrium-90 PET/CT - part 2: dose-response and tumor predictive dosimetry for resin microspheres  

PubMed Central

Background Coincidence imaging of low-abundance yttrium-90 (90Y) internal pair production by positron emission tomography with integrated computed tomography (PET/CT) achieves high-resolution imaging of post-radioembolization microsphere biodistribution. Part 2 analyzes tumor and non-target tissue dose-response by 90Y PET quantification and evaluates the accuracy of tumor 99mTc macroaggregated albumin (MAA) single-photon emission computed tomography with integrated CT (SPECT/CT) predictive dosimetry. Methods Retrospective dose quantification of 90Y resin microspheres was performed on the same 23-patient data set in part 1. Phantom studies were performed to assure quantitative accuracy of our time-of-flight lutetium-yttrium-oxyorthosilicate system. Dose-responses were analyzed using 90Y dose-volume histograms (DVHs) by PET voxel dosimetry or mean absorbed doses by Medical Internal Radiation Dose macrodosimetry, correlated to follow-up imaging or clinical findings. Intended tumor mean doses by predictive dosimetry were compared to doses by 90Y PET. Results Phantom studies demonstrated near-perfect detector linearity and high tumor quantitative accuracy. For hepatocellular carcinomas, complete responses were generally achieved at D70 > 100 Gy (D70, minimum dose to 70% tumor volume), whereas incomplete responses were generally at D70 < 100 Gy; smaller tumors (<80 cm3) achieved D70 > 100 Gy more easily than larger tumors. There was complete response in a cholangiocarcinoma at D70 90 Gy and partial response in an adrenal gastrointestinal stromal tumor metastasis at D70 53 Gy. In two patients, a mean dose of 18 Gy to the stomach was asymptomatic, 49 Gy caused gastritis, 65 Gy caused ulceration, and 53 Gy caused duodenitis. In one patient, a bilateral kidney mean dose of 9 Gy (V20 8%) did not cause clinically relevant nephrotoxicity. Under near-ideal dosimetric conditions, there was excellent correlation between intended tumor mean doses by predictive dosimetry and those by 90Y PET, with a low median relative error of +3.8% (95% confidence interval, -1.2% to +13.2%). Conclusions Tumor and non-target tissue absorbed dose quantification by 90Y PET is accurate and yields radiobiologically meaningful dose-response information to guide adjuvant or mitigative action. Tumor 99mTc MAA SPECT/CT predictive dosimetry is feasible. 90Y DVHs may guide future techniques in predictive dosimetry. PMID:23885971

2013-01-01

195

Why There Are 88 Keys on the Piano: "88 Logic-The Mackay Method for Piano." Volume 1  

ERIC Educational Resources Information Center

Background: After trying to define the reason why the piano ended up with 88 keys, I found patterns to explain ways of playing the piano with an 8:8 ratio which gives purpose to why the piano has 88 keys on it. Purpose: The first purpose is to enable piano teachers and music students to benefit from understanding how to play piano and be…

Mackay, Stephen R.

2005-01-01

196

Intrinsic trapping sites in rare-earth and yttrium oxyorthosilicates D. W. Cooke,a)  

E-print Network

Intrinsic trapping sites in rare-earth and yttrium oxyorthosilicates D. W. Cooke,a) B. L. Bennett spectrum observed in undoped LSO is ascribed to transitions of low-level rare-earth impurities. Regardless associated with the configuration of oxygen ions in the vicinity of the host rare-earth ions. The presence

197

Preliminary results on a new method for producing yttrium phosphorous microspheres.  

PubMed

This paper reports on a new method to embed phosphorus particles into the matrix of yttrium aluminum silicate microspheres. Yttrium phosphorus glass microspheres about 20µm in size were obtained when an aqueous solution of YCl3 and AlCl3 were added to tetraethyl orthosilicate (TEOS) (phosphoric acid was used to catalyze the hydrolysis and condensation of TEOS) and was pumped into silicone oil under constant stirring. The shapes of the particles produced by this method are regular and nearly spheric in shape. Paper chromatography was used to determine the radiochemical impurity of radioactive microspheres. Radionuclide purity was determined using a gamma spectrometry system and an ultra-low level liquid scintillation spectrometer. The P(+) ions implantation stage was eliminated by embedding phosphorus particles in the matrix of the glass microspheres. This paper shows that a high temperature is not required to produce yttrium phosphorus aluminum silicate microspheres. The result shows that the silicone oil spheroidization method is a very suitable way to produce yttrium phosphorus glass microspheres. The topographical analysis of microspheres shows that the Y, P, Si, and Al elements are distributed in the microspheres and the distribution of elements in the samples is homogenous. PMID:24998745

Ghahramani, M R; Garibov, A A; Agayev, T N

2014-09-01

198

Solid state battery with pure and doped sodium yttrium fluoride as the solid electrolyte  

Microsoft Academic Search

Solid state batteries using pure and doped sodium yttrium fluoride as the solid electrolytes were fabricated at ambient temperature. The discharge characteristics of the cells for a load of 1 M Omega were studied. The cell with NaYF4:Dy as the solid electrolyte exhibited a larger plateau region compared with the other cells. Open circuit voltage and short circuit current of

M. Shareefuddin; M. Jamal; M. Narasimha Chary

1995-01-01

199

THE THERMAL DECOMPOSITION OF YTTRIUM AND THE RARE EARTH METAL SULPHATE HYDRATES  

Microsoft Academic Search

The thermal decompositin of lanthanum, cerium (III), praseodymium, ; neodymium, samarium, gadolinium, dysprosium, holmiuun, erbium, ytterbium, and ; yttrium sulfate hydrates was studied on the thermobalance. The formation of ; intermediate hydrates was more pronounced with the lighter rare earth elements ; than with the heavier ones. The first weight loss temperatures for the hydrated ; salts ranged from 40

Wesley W. Wendlandt

1958-01-01

200

Al NMR study of the structure of lanthanum and yttrium based aluminosilicate glasses and melts  

E-print Network

A 27 Al NMR study of the structure of lanthanum and yttrium based aluminosilicate glasses and melts allowed to follow selected samples from 2200°C down to 1700°C and hence to characterize the aluminum of glasses has a large range of applications in modern technology like (a) host materials for laser, optical

Paris-Sud XI, Université de

201

DOMAIN STRUCTURES OF MONOCRYSTALS OF THE FERRITIES OF YTTRIUM, HOLMIUM, ERBIUM, AND GADOLINIUM  

Microsoft Academic Search

The response of the domain structure to magnetic fields for the ferrites ; of Y, Ho, Er, and Gd as monocrystals is described. The domain structure on (110) ; for yttrium ferrite was the same as in isometric crystals. Figures on (211) were ; examined for the other ferrites. Erbium ferrite closely resembled holmium ; ferrite. The gadolinium ferrite showed

A. I. Drokin; V. D. Dylgerov; B. V. Beznosikov

1962-01-01

202

COMPLEXOMETRIC TITRATION OF YTTRIUM AND THE LANTHANONS. I. A COMPARISON OF DIRECT METHODS  

Microsoft Academic Search

A comparison was made of a number of direct complexometric titrations ; previously published ior the determination of yttrium and the lanthanons. ; Working and optimum pH ranges were obtained for what are considered to be the ; best indicators, Alizarin Red S screened with Methylene Blue, Eriochrome Black T, ; Copper-Naphthyl Azoxine, and Xylenol Orange. The precision and accuracy

S. J. Lyle

1963-01-01

203

Project 88: Parent Participation in the Elementary School.  

ERIC Educational Resources Information Center

The program described in this paper illustrates the extension of teaching to parents and older children. Project 88, so-called because of the 88 children who were involved during the first year of the program in 1969, is a parent participation program that included a kindergarten, a first grade, and an interage 4-5-6 combination at the Castro…

Elliott, David L.

204

10 CFR 71.88 - Air transport of plutonium.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 2012-01-01 false Air transport of plutonium. 71.88 Section...Controls and Procedures § 71.88 Air transport of plutonium. (a...or delivered to a carrier for air transport unless: (1) The...

2012-01-01

205

10 CFR 71.88 - Air transport of plutonium.  

Code of Federal Regulations, 2010 CFR

...2010-01-01 2010-01-01 false Air transport of plutonium. 71.88 Section...Controls and Procedures § 71.88 Air transport of plutonium. (a...or delivered to a carrier for air transport unless: (1) The...

2010-01-01

206

10 CFR 71.88 - Air transport of plutonium.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Air transport of plutonium. 71.88 Section...Controls and Procedures § 71.88 Air transport of plutonium. (a...or delivered to a carrier for air transport unless: (1) The...

2013-01-01

207

10 CFR 71.88 - Air transport of plutonium.  

...2014-01-01 2014-01-01 false Air transport of plutonium. 71.88 Section...Controls and Procedures § 71.88 Air transport of plutonium. (a...or delivered to a carrier for air transport unless: (1) The...

2014-01-01

208

10 CFR 71.88 - Air transport of plutonium.  

Code of Federal Regulations, 2011 CFR

...2011-01-01 2011-01-01 false Air transport of plutonium. 71.88 Section...Controls and Procedures § 71.88 Air transport of plutonium. (a...or delivered to a carrier for air transport unless: (1) The...

2011-01-01

209

47 CFR 80.88 - Secrecy of communication.  

Code of Federal Regulations, 2013 CFR

47 ? Telecommunication ? 5 ? 2013-10-01 ? 2013-10-01 ? false ? Secrecy of communication. ? 80.88 ? Section 80.88 ? Telecommunication ? FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) ? SAFETY AND SPECIAL RADIO SERVICES ? STATIONS IN THE MARITIME SERVICES ? Operating Requirements and Procedures...

2013-10-01

210

47 CFR 80.88 - Secrecy of communication.  

Code of Federal Regulations, 2012 CFR

47 ? Telecommunication ? 5 ? 2012-10-01 ? 2012-10-01 ? false ? Secrecy of communication. ? 80.88 ? Section 80.88 ? Telecommunication ? FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) ? SAFETY AND SPECIAL RADIO SERVICES ? STATIONS IN THE MARITIME SERVICES ? Operating Requirements and Procedures...

2012-10-01

211

ISI TechnicalManual ISI/TM-88-197  

E-print Network

ISI TechnicalManual ISI/TM-88-197 February1988 University ofSouthern California Gabriel Robins %% ... ... .. The ISI Grapher Manual INFORMATION SCIENCES 213/822-1511 INSTITUTEJ f-"-676 292-t5466Admiralty Way. MONITORING ORGANIZATION REPORT NUMBER(S) ISI/TM-88-197 6a. NAME OF PERFORMING ORGANIZATION USC

Robins, Gabriel

212

ISI ReprintSeries ISIIRS-88-210  

E-print Network

ISI ReprintSeries ISIIRS-88-210 June1988 University ofSouthern California Gabriel Robins Applications of the ISI Grapher Reprinted from Proceedingsof the ArtificialIntelligenceand Advanced Computer PERFORMING ORGANIZATION REPORT NUMBER(S) 5. MONITORING ORGANIZATION REPORT NUMBER(S) ISI/RS-88

Robins, Gabriel

213

Effects of yttrium, aluminum and chromium concentrations in bond coatings on the performance of zirconia-yttria thermal barriers  

NASA Technical Reports Server (NTRS)

A cyclic furnace study was conducted on thermal barrier systems to evaluate the effects of yttrium, chromium and aluminum in nickel-base alloy bond coatings and the influence of the bond coating thickness on yttria-stabilized zirconia thermal barrier coating lifetimes. Without yttrium in the bond coatings, the zirconia coatings failed very rapidly. Increasing concentrations of chromium and aluminum in the Ni-Cr-Al-Y bond coatings increased the total coating lifetimes. This effect was not as great as that due to yttrium. Increased bond coating thickness was also found to increase the lifetimes.

Stecura, S.

1980-01-01

214

Effects of yttrium, aluminum and chromium concentrations in bond coatings on the performance of zirconia-yttria thermal barriers  

NASA Technical Reports Server (NTRS)

A cyclic furnace study was conducted on thermal barrier systems to evaluate the effects of yttrium, chromium, and aluminum in nickel-base alloy bond coatings and the effect of bond coating thickness on yttria-stabilized zirconia thermal barrier coating life. Without yttrium in the bond coatings, the zirconia coatings failed very rapidly. Increasing chromium and aluminum in the Ni-Cr-Al-Y bond coatings increased total coating life. This effect was not as great as that due to yttrium. Increased bond coat thickness was also found to increase life.

Stecura, S.

1980-01-01

215

Effects of yttrium, aluminum and chromium concentrations in bond coatings on the performance of zirconia-yttria thermal barriers  

NASA Technical Reports Server (NTRS)

A cyclic furnace study was conducted on thermal barrier systems to evaluate the effects of yttrium, chromium and aluminum in nickel-base alloy bond coatings and the effect of bond coating thickness on yttria-stabilized zirconia thermal barrier coating life. Without yttrium in the bond coatings, the zirconia coatings failed very rapidly. Increasing chromium and aluminum in the Ni-Cr-Al-Y bond coatings increased total coating life. This effect was not as great as that due to yttrium. Increased bond coat thickness was also found to increase life.

Stecura, S.

1980-01-01

216

Electrodeposition of cobalt–yttrium hydroxide\\/oxide nanocomposite films from particle-free aqueous baths containing chloride salts  

Microsoft Academic Search

The feasibility of growing nanostructured films composed of cobalt and yttrium hydroxide\\/oxide phases by electrodeposition is demonstrated. Particle-free aqueous solutions containing YCl3 and CoCl2 salts and glycine were used. The incorporation of yttrium compounds into the cobalt deposit was achieved using pulse deposition (ton=0.1ms, toff=0.9ms) and for cathodic pulses higher than ?500mAcm?2. Deposits obtained were crack-free, typically with 1–5wt% yttrium,

K. M. Sivaraman; O. Ergeneman; S. Pané; E. Pellicer; J. Sort; K. Shou; S. Suriñach; M. D. Baró; B. J. Nelson

2011-01-01

217

Bulletin of the College of Engineering, N.T.U., No. 88, June 2003, pp. 1322 DESIGN AND IMPLEMENTATION OF  

E-print Network

13­22 Bulletin of the College of Engineering, N.T.U., No. 88, June 2003, pp. 13­22 13 AES-library technology. The simulation result shows that the AES chip works at 70MHz clock and the target throughput rate communication systems, users have a great demand for secure mechanisms for data transmission over the non

Hung, Shih-Hao

218

http://www.sjsu.edu/senate/f88-5.htm F88-5 CONTINUING EDUCATION COMMITTEE  

E-print Network

related to Continuing Education and ITFS (Instructional Television Fixed Service Channels) activitieshttp://www.sjsu.edu/senate/f88-5.htm F88-5 CONTINUING EDUCATION COMMITTEE Legislative History. That Continuing Education and other certificate programs be subject to review by the Curriculum Committee

Gleixner, Stacy

219

Increased Serum GP88 (Progranulin) Concentrations in Rheumatoid Arthritis.  

PubMed

GP88 (Progranulin; PGRN) is a secreted glycosylated protein with important functions in several processes, including immune response and cancer growth. Recent reports have shown that PGRN is a therapeutic target for rheumatoid arthritis (RA) because of its capability to bind with tumor necrosis factor receptor (TNFR). However, the serum PGRN level in RA patients has not been investigated. We used enzyme-linked immunosorbent assay (ELISA) to quantify the serum levels of PGRN in 417 healthy subjects, 56 patients with RA and 31 patients with osteoarthritis (OA). In RA patients, we also measured the serum TNF-? and sTNFR concentration. Immunohistochemical staining of PGRN was performed using synovectomy tissue of RA patients. The serum PGRN normal range was established as 40.1?±?8.7 ng/ml. PGRN levels were not influenced by sex or age. A significant increase in serum PGRN levels was observed in RA (50.2?±?11.1 ng/ml) and OA (45.4?±?6.6 ng/ml) groups compared to those in age-matched healthy controls (40.4?±?9.9 ng/ml) (p?

Yamamoto, Yasuko; Takemura, Masao; Serrero, Ginette; Hayashi, Jun; Yue, Binbin; Tsuboi, Aya; Kubo, Hisako; Mitsuhashi, Takashi; Mannami, Kenji; Sato, Masao; Matsunami, Hidetoshi; Matuo, Yushi; Saito, Kuniaki

2014-10-01

220

Cutaneous human papillomavirus 88: remarkable differences in viral load.  

PubMed

A human papillomavirus (HPV) was cloned from a patient with multiple squamous cell carcinomas (SCCs) and identified as HPV88, recently categorized into a new species within the genus Gamma. The HPV88 viral load in an SCC of the index patient exceeded 1 million copies/cell. By contrast, a survey of 447 skin lesions (79 actinic keratoses, 73 seborrhoeic keratoses, 169 basal cell carcinomas and 126 SCCs) and 362 healthy skin biopsies found detectable HPV88 DNA in only 7 specimens. All these had very low viral loads (<1 copy/10(3) cells) implying extreme biological variability in viral load. PMID:17935140

Kullander, Johanna; Handisurya, Alessandra; Forslund, Ola; Geusau, Alexandra; Kirnbauer, Reinhard; Dillner, Joakim

2008-01-15

221

Verification of d-wave pairing symmetry by microwave intermodulation distortion measurements in yttrium barium copper oxide  

E-print Network

We report measurements of the temperature and power dependence of the microwave frequency intermodulation distortion (IMD) in high quality pulsed laser deposition (PLD) Yttrium Barium Copper Oxide (YBCO) on LaAlO3 substrate. ...

Park, Sang-Hoon, Ph. D. Massachusetts Institute of Technology

2004-01-01

222

Effects of yttrium, aluminum, and chromium concentrations in bond coatings on the performance of zirconia-yttria thermal barriers  

NASA Technical Reports Server (NTRS)

A cyclic furnace study was conducted between 990 - 280 C and 1095 - 280 C to evaluate the effects of yttrium, chromium, and aluminum concentrations in nickel base alloy bond coatings and also the effect of the bond coating thickness on the performance of yttria-stabilized zirconia thermal barrier coatings. The presence and the concentration of yttrium is very critical. Without yttrium, rapid oxidation of Ni-Al, Ni-Cr, and Ni-Cr-Al bond coatings causes zirconia thermal barrier coatings to fail very rapidly. Concentrations of chrominum and aluminum in Ni-Cr-Al-Y bond coating have a very significant effect on the thermal barrier coating life. This effect, however, is not as great as that due to yttrium. Furthermore, the thickness and the thickness uniformity also have a very significant effect on the life of the thermal barrier system.

Stecura, S.

1979-01-01

223

Impact of yttrium ion implantation on corrosion behavior of laser beam welded zircaloy-4 in sulfuric acid solution  

Microsoft Academic Search

In order to study the effect of yttrium ion implantation on the aqueous corrosion behavior of laser beam welded zircaloy-4 (LBWZr4), The butt weld joint of zircaloy-4 was made by means of a carbon dioxide laser, subsequently the LBWZr4 samples were implanted with yttrium ion using a MEVVA source at an energy of 40keV, with a fluence range from 1×1016

Qian Wan; Xinde Bai; Xiaoyang Liu

2005-01-01

224

42 CFR 88.3 - Eligibility-currently identified responders.  

Code of Federal Regulations, 2012 CFR

...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.3 Eligibility—currently...between NIOSH and the consortium administered by Mount Sinai School of Medicine in New York City and the Fire Department,...

2012-10-01

225

42 CFR 88.3 - Eligibility-currently identified responders.  

Code of Federal Regulations, 2011 CFR

...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.3 Eligibility—currently...between NIOSH and the consortium administered by Mount Sinai School of Medicine in New York City and the Fire Department,...

2011-10-01

226

42 CFR 88.3 - Eligibility-currently identified responders.  

Code of Federal Regulations, 2013 CFR

...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.3 Eligibility—currently...between NIOSH and the consortium administered by Mount Sinai School of Medicine in New York City and the Fire Department,...

2013-10-01

227

BOOK REVIEWS Journal of Mammalogy, 88(3):824, 2007  

E-print Network

BOOK REVIEWS Journal of Mammalogy, 88(3):824, 2007 Thorington, R. W., Jr., and K. E. Ferrell. 2006 squirrel [Petaurillus emiliae]) or as large as a medium-sized carnivore (8.5 kg--gray marmot [Marmota

Baker, Robert J.

228

40 CFR 146.88 - Injection well operating requirements.  

...2014-07-01 2014-07-01 false Injection well operating requirements. 146...Class VI Wells § 146.88 Injection well operating requirements. ...maintain mechanical integrity of the injection well at all times. (e) The...

2014-07-01

229

28 CFR 115.88 - Data review for corrective action.  

...Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Data Collection and Review § 115.88 Data review for corrective action. (a) The agency shall review data...

2014-07-01

230

Vol. 88, No. 10, 1998 1087 Ecology and Population Biology  

E-print Network

that genetic drift and gene flow were not major contributors to genetic structure, while asexual reproduction in a sorghum disease nursery. Phytopathology 88:1087-1093. Restriction fragment length polymorphisms (RFLPs

McDonald, Bruce

231

7 CFR 989.88 - Duration of immunities.  

Code of Federal Regulations, 2011 CFR

...MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE RAISINS PRODUCED FROM GRAPES GROWN IN CALIFORNIA Order Regulating Handling Miscellaneous Provisions § 989.88 Duration of immunities. The...

2011-01-01

232

21 CFR 520.88d - Amoxicillin trihydrate soluble powder.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Amoxicillin trihydrate soluble powder. 520...ANIMAL DRUGS § 520.88d Amoxicillin trihydrate soluble powder. (a...Specifications. Each gram contains amoxicillin trihydrate equivalent to 115.4...

2010-04-01

233

21 CFR 520.88c - Amoxicillin trihydrate oral suspension.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Amoxicillin trihydrate oral suspension. 520...ANIMAL DRUGS § 520.88c Amoxicillin trihydrate oral suspension. (a...8-milliliter dose contains amoxicillin trihydrate equivalent to 40...

2010-04-01

234

21 CFR 526.88 - Amoxicillin trihydrate for intramammary infusion.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Amoxicillin trihydrate for intramammary infusion...DOSAGE FORMS § 526.88 Amoxicillin trihydrate for intramammary infusion...single dose syringe contains amoxicillin trihydrate equivalent to 62.5...

2010-04-01

235

21 CFR 522.88 - Sterile amoxicillin trihydrate for suspension.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Sterile amoxicillin trihydrate for suspension. 522... § 522.88 Sterile amoxicillin trihydrate for suspension. (a...vial contains 3 grams of amoxicillin as the trihydrate. The powder is...

2010-04-01

236

40 CFR 146.88 - Injection well operating requirements.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Injection well operating requirements. 146...Class VI Wells § 146.88 Injection well operating requirements. ...maintain mechanical integrity of the injection well at all times. (e) The...

2013-07-01

237

40 CFR 146.88 - Injection well operating requirements.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Injection well operating requirements. 146...Class VI Wells § 146.88 Injection well operating requirements. ...maintain mechanical integrity of the injection well at all times. (e) The...

2011-07-01

238

40 CFR 146.88 - Injection well operating requirements.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Injection well operating requirements. 146...Class VI Wells § 146.88 Injection well operating requirements. ...maintain mechanical integrity of the injection well at all times. (e) The...

2012-07-01

239

40 CFR 86.603-88 - Test orders.  

Code of Federal Regulations, 2010 CFR

...CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES (CONTINUED) Selective Enforcement Auditing of New Light-Duty Vehicles, Light-Duty Trucks, and Heavy-Duty Vehicles § 86.603-88 Test orders....

2010-07-01

240

88. Historic American Buildings Survey, Donald W. Dickensheets, Photographer. July ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. Historic American Buildings Survey, Donald W. Dickensheets, Photographer. July 6, 1940. ANGEL, WEST SIDE MAIN ALTAR (SOUTHEAST ELEVATION). - San Xavier del Bac Mission, Mission Road, Tucson, Pima County, AZ

241

88. Reproduction from glass plate negative (original in Modjeski and ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. Reproduction from glass plate negative (original in Modjeski and Masters office, Harrisburg, Pennsylvania, Modjeski Collection, No. 4, not dated) LOOKING DOWNSTREAM - Burlington Northern Railroad Bridge, Spanning Willamette River at River Mile 6.9, Portland, Multnomah County, OR

242

38 CFR 21.88 - Individualized employment assistance plan.  

... Pensions, Bonuses, and Veterans' Relief 2 2014-07-01...2014-07-01 false Individualized employment assistance plan. 21.88... Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED)...

2014-07-01

243

40 CFR 87.83-87.88 - [Reserved  

Code of Federal Regulations, 2010 CFR

...PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM AIRCRAFT AND AIRCRAFT ENGINES Test Procedures for Engine Smoke Emissions (Aircraft Gas Turbine Engines) §§ 87.83-87.88...

2010-07-01

244

40 CFR 144.88 - What are the additional requirements?  

Code of Federal Regulations, 2010 CFR

...Owners and Operators of Class V Injection Wells § 144.88 What are the additional...Preclosure Notification for Closure of Injection Wells,” At least 30 days prior...Preclosure Notification for Closure of Injection Wells”. At least 30 days...

2010-07-01

245

42 CFR 88.15 - Appeals regarding treatment.  

Code of Federal Regulations, 2013 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.15 Appeals regarding treatment. (a) Individuals may appeal the following...

2013-10-01

246

42 CFR 88.7 - Eligibility-currently identified survivors.  

Code of Federal Regulations, 2011 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.7 Eligibility—currently identified survivors. (a) Survivors who have been...

2011-10-01

247

42 CFR 88.7 - Eligibility-currently identified survivors.  

Code of Federal Regulations, 2012 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.7 Eligibility—currently identified survivors. (a) Survivors who have been...

2012-10-01

248

42 CFR 88.14 - Standard for determining medical necessity.  

Code of Federal Regulations, 2012 CFR

...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.14 Standard for determining...the medical treatment protocols developed by the Data Centers and approved by the WTC Program...

2012-10-01

249

42 CFR 88.14 - Standard for determining medical necessity.  

Code of Federal Regulations, 2011 CFR

...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.14 Standard for determining...the medical treatment protocols developed by the Data Centers and approved by the WTC Program...

2011-10-01

250

42 CFR 88.15 - Appeals regarding treatment.  

Code of Federal Regulations, 2012 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.15 Appeals regarding treatment. (a) Individuals may appeal the following...

2012-10-01

251

42 CFR 88.14 - Standard for determining medical necessity.  

Code of Federal Regulations, 2013 CFR

...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.14 Standard for determining...the medical treatment protocols developed by the Data Centers and approved by the WTC Program...

2013-10-01

252

42 CFR 88.7 - Eligibility-currently identified survivors.  

Code of Federal Regulations, 2013 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.7 Eligibility—currently identified survivors. (a) Survivors who have been...

2013-10-01

253

42 CFR 88.15 - Appeals regarding treatment.  

Code of Federal Regulations, 2011 CFR

...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.15 Appeals regarding treatment. (a) Individuals may appeal the following...

2011-10-01

254

42 CFR 32.88 - Examinations and treatment.  

Code of Federal Regulations, 2010 CFR

...HEALTH AND HUMAN SERVICES MEDICAL CARE AND EXAMINATIONS MEDICAL CARE FOR PERSONS WITH HANSEN'S DISEASE AND OTHER PERSONS IN EMERGENCIES Persons with Hansen's Disease § 32.88 Examinations and treatment. Patients will be provided...

2010-10-01

255

88. North and west facades of powerhouse; looking southeast. Photo ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. North and west facades of powerhouse; looking southeast. Photo by Jet Lowe, HAER, 1989. - Puget Sound Power & Light Company, White River Hydroelectric Project, 600 North River Avenue, Dieringer, Pierce County, WA

256

A WSR-88D Approach to Waterspout Forecasting  

Microsoft Academic Search

Abstract The WSR-88D is being installed at National Weather Service (NWS) forecast and warning offices and many,military installations across the county. The added capabilities of the WSR-88D over conventional radar provides the forecaster a multitude of products which allow a more complete interrogation of small scale weather features. In Florida, waterspouts and weak tornadoes account for much of the state's

Lt Barry K. Choy; Noaa Corps; Scott M. Spratt

257

Unresponsiveness of MyD88Deficient Mice to Endotoxin  

Microsoft Academic Search

MyD88 is a general adaptor protein that plays an important role in the Toll\\/IL-1 receptor family signalings. Recently, Toll-like receptors 2 and 4 (TLR2 and TLR4) have been suggested to be the signaling receptors for lipopolysaccharide (LPS). In this study, we demonstrate that MyD88 knockout mice lack the ability to respond to LPS as measured by shock response, B cell

Taro Kawai; Osamu Adachi; Tomohiko Ogawa; Kiyoshi Takeda; Shizuo Akira

1999-01-01

258

MyD88 and its divergent toll in carcinogenesis  

PubMed Central

Toll-like and interleukin-1 (IL-1) family receptors recognize microbial or endogenous ligands and inflammatory mediators, respectively, and with the exception of Toll-like receptor 3 (TLR3), signal via the adaptor molecule myeloid differentiation factor 88 (MyD88). MyD88 is involved in oncogene-induced cell intrinsic inflammation and in cancer-associated extrinsic inflammation, and as such MyD88 contributes to skin, liver, pancreatic, and colon carcinogenesis, as well as sarcomagenesis. MyD88 is also protective, for example in oncogenic virus carcinogenesis or, acting downstream of IL-18R to strengthen mucosal repair, in azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colon carcinogenesis. Here, we discuss the mechanisms of the divergent effects of MyD88 and the balance of its protumor role in cancer-enhancing inflammation and immunity and its antitumor role in tissue homeostasis, repair, and immunity against the tumor or oncogenic pathogens. PMID:23660392

Salcedo, Rosalba; Cataisson, Christophe; Hasan, Uzma; Yuspa, Stuart H.; Trinchieri, Giorgio

2013-01-01

259

Exceptional field theory. III. E8(8)  

NASA Astrophysics Data System (ADS)

We develop exceptional field theory for E8(8), defined on a (3+248)-dimensional generalized spacetime with extended coordinates in the adjoint representation of E8(8). The fields transform under E8(8) generalized diffeomorphisms and are subject to covariant section constraints. The bosonic fields include an "internal" dreibein and an E8(8)-valued "zweihundertachtundvierzigbein" (248-bein). Crucially, the theory also features gauge vectors for the E8(8) E bracket governing the generalized diffeomorphism algebra and covariantly constrained gauge vectors for a separate but constrained E8(8) gauge symmetry. The complete bosonic theory, with a novel Chern-Simons term for the gauge vectors, is uniquely determined by gauge invariance under internal and external generalized diffeomorphisms. The theory consistently comprises components of the dual graviton encoded in the 248-bein. Upon picking particular solutions of the constraints the theory reduces to D =11 or type IIB supergravity, for which the dual graviton becomes pure gauge. This resolves the dual graviton problem, as we discuss in detail.

Hohm, Olaf; Samtleben, Henning

2014-09-01

260

Samarium solubility in an yttrium- and gadolinium-containing magnesium-based solid solution  

NASA Astrophysics Data System (ADS)

Metallographic, X-ray diffraction, and electron microprobe analyses and electrical resistivity measurements are used to study the samarium solubility in a magnesium-based solid solution containing equal fractions of yttrium and gadolinium at 500, 400, and 300°C. The regions of existence of the magnesium-based solid solution at these temperatures and the phases in equilibrium with this solid solution are determined. The magnesium solid solution is found to be in equilibrium only with the Mg41Sm5 and Mg24(Y, Gd)5 phases, which belong to the binary Mg-Sm and Mg-Y-Gd systems, respectively. These results are used to construct isothermal sections of the Mg-Y-Gd-Sm phase diagram at 500, 400, and 300°C and equal yttrium and gadolinium contents in the region adjacent to the magnesium solid solution.

Luk'yanova, E. A.; Rokhlin, L. L.; Dobatkina, T. V.; Korol'kova, I. G.

2012-07-01

261

Bulky Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Treated with Yttrium-90 Ibritumomab Tiuxetan  

PubMed Central

An 84-year-old woman was admitted to our hospital with nonproductive cough and dyspnea on exertion. Computed tomography (CT) scan revealed extensive consolidation in the right lung. She was diagnosed with pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma using CT-guided lung biopsy. Her pulmonary images and respiratory symptoms did not improve two months after receiving 4 cycles of rituximab weekly; therefore, yttrium-90 ibritumomab tiuxetan was chosen as salvage therapy. The abnormal shadow on her pulmonary images was significantly reduced two months later, and she had no symptoms without nonhematological toxicities. She has had no progression for 18 months. Furthermore, radiation pneumonitis has not also been observed. We herein reported bulky pulmonary MALT lymphoma treated with yttrium-90 ibritumomab tiuxetan. PMID:24371530

Tamura, Shinobu; Ikeda, Tokuji; Kurihara, Toshio; Kakuno, Yoshiteru; Nasu, Hideki; Nakano, Yoshio; Oshima, Koichi; Fujimoto, Tokuzo

2013-01-01

262

Co-sputtering yttrium into hafnium oxide thin films to produce ferroelectric properties  

SciTech Connect

Thin film capacitors were fabricated by sputtering TiN-Y doped HfO{sub 2}-TiN stacks on silicon substrates. Yttrium was incorporated into the HfO{sub 2} layers by simultaneously sputtering from Y{sub 2}O{sub 3} and HfO{sub 2} sources. Electric polarization and relative permittivity measurements yield distinct ferroelectric properties as a result of low yttrium dopant concentrations in the range of 0.9-1.9 mol. %. Grazing incidence x-ray diffraction measurements show the formation of an orthorhombic phase in this range. Compared to atomic layer deposition films, the highest remanent polarization and the highest relative permittivity were obtained at significantly lower doping concentrations in these sputtered films.

Olsen, T. [NaMLab gGmbH, 01187 Dresden (Germany); Department of Electrical and Computer Engineering, University of Alberta, Edmonton T6G 2V4 (Canada); Schroeder, U.; Mueller, S.; Krause, A.; Martin, D.; Singh, A. [NaMLab gGmbH, 01187 Dresden (Germany); Mueller, J. [Fraunhofer CNT, 01099 Dresden (Germany); Geidel, M. [Institute of Semiconductors and Microsystems, Technische Universitaet Dresden, 01062 Dresden (Germany); Mikolajick, T. [NaMLab gGmbH, 01187 Dresden (Germany); Institute of Semiconductors and Microsystems, Technische Universitaet Dresden, 01062 Dresden (Germany)

2012-08-20

263

Boehmite and yttrium oxide coatings on silicon nitride from aqueous sols  

SciTech Connect

To improve the processing of silicon nitride, boehmite and yttrium oxide were coated on silicon nitride particles by an aqueous sol-gel method. It is shown that boehmite and Y{sub 2}O{sub 3} can be coated on Si{sub 3}N{sub 4} particles from aqueous solutions. However, the Y{sub 2}O{sub 3} coating is not as complete as boehmite coating. The coating of a yttria coating followed by a boehmite coating was attempted and the TEM showed a coating twice as thick as the Y{sub 2}O{sub 3} or AlOOH coating. Hydrothermal treatment of yttrium nitrate hydrous hydroxide results in the formation and growth of Y(OH){sub 3} fibers which can be calcined and transformed into Y{sub 2}O{sub 3} fibers at 500 C.

Buchta, M.; Shih, W.H. [Drexel Univ., Philadelphia, PA (United States). Dept. of Materials Engineering

1997-08-01

264

Synthesis of aluminum garnets of rare-earth elements and yttrium with combined deposition of hydroxides  

Microsoft Academic Search

This work is concerned with the study of the mechanism of the formation of aluminum garnets of rare-earth elements as well as the conditions for their synthesis by the method of combined deposition of hydroxides. The deposition was conducted by continuously dripping a mixture of a 0.5 M solution of nitric acid salts of aluminum and rare-earth elements or yttrium

V. B. Glushkova; S. Yu. Zinovev; V. A. Krzhizhanovskaya; A. K. Kuznetsov

1986-01-01

265

Physical properties of natively textured yttrium doped zinc oxide films by sol-gel  

Microsoft Academic Search

Sol-gel derived yttrium doped ZnO films of various thicknesses have been deposited by the dip coating technique. The investigations of microstructural, electrical and optical properties of post heat-treated films in air as a function of thickness have been made. It is found that high quality films are obtained at an annealing temperature of 550 ?C. The (002) preferential growth of

R. Kaur; A. V. Singh; R. M. Mehra

2005-01-01

266

Low Temperature Resistivity of Yttrium-Based Alloys Containing Small Amounts of Rare Earth Metals  

Microsoft Academic Search

The resistivity of the dilute alloys of rare earth metals with yttrium has been measured at low temperatures. The result is in qualitative agreement with the recent theories due to Kondo and others on the s--d or s--f scattering. The effective s--f exchange integrals for various rare-earth solutes have been derived from the analysis of the resistivity data and compared

Tadashi Sugawara

1965-01-01

267

Self-Generation of Microwave Magnetic Envelope Soliton Trains in Yttrium Iron Garnet Thin Films  

Microsoft Academic Search

The self-generation of microwave magnetic envelope solitons in magnetic films has been realized for the first time. Solitons with a width of 20 ns and a carrier frequency of 5.1555 GHz were generated for the magnetostatic backward volume wave (MSBVW) configuration in a 5.2 mum thick yttrium iron garnet film. The film and MSBVW propagation structure were part of a

Boris A. Kalinikos; Nikolai G. Kovshikov; Carl E. Patton

1998-01-01

268

Interface reactions during processing of chemical vapor deposited yttrium oxide high-k dielectrics  

Microsoft Academic Search

High dielectric constant (high-k) insulators are important for advanced MOS devices to limit gate leakage and increase gate capacitance. Reactions between high-k's and the substrate during deposition or post-deposition processing lead to an increase in the equivalent oxide thickness, and the mechanisms that control the changes need to be well understood. We investigate yttrium-based high-k dielectrics formed by oxygen plasma

Dong Niu

2002-01-01

269

Thermal behaviour of gel-grown pure and mixed rare earth tartrates of yttrium and samarium  

Microsoft Academic Search

Thermal behaviour of gel-grown pure and mixed rare earth tartrates of yttrium and samarium is investigated using thermogravimetric\\u000a analysis (TGA) and differential scanning calorimetry (DSC). The thermal behaviour suggests that the materials are unstable\\u000a at lower energies and pass through various stages of decomposition, decomposing to respective rare earth oxides which remain\\u000a stable on further heating. It is estimated that

Anima Jain; Sushma Bhat; Sanjay Pandita; M L Kaul; P N Kotru

1997-01-01

270

Hepatic Abscess After Yttrium-90 Radioembolization for Islet-Cell Tumor Hepatic Metastasis  

SciTech Connect

Infectious complications after yttrium-90 (y-90) radioembolization of hepatic tumors are rare. Most reports describe hepatic abscesses as complications of other locoregional therapies, such as transcatheter arterial embolization or chemoembolization. These usually occur in patients with a history of biliary intervention and present several weeks after treatment. We report a case of hepatic abscess formed immediately after y-90 radioembolization of a hepatic metastasis in a patient who had no history of previous biliary instrumentation.

Mascarenhas, Neil B., E-mail: neilmascarenhas1@gmail.co [Northwestern Memorial Hospital, Department of Radiology, Section of Interventional Radiology (United States); Mulcahy, Mary F. [Robert H Lurie Comprehensive Cancer Center, Northwestern Memorial Hospital, Department of Medicine, Division of Hematology and Oncology (United States); Lewandowski, Robert J.; Salem, Riad; Ryu, Robert K., E-mail: rryu@nmff.or [Northwestern Memorial Hospital, Department of Radiology, Section of Interventional Radiology (United States)

2010-06-15

271

Microanalytical study of the hexagonal phase in an yttrium-containing low expansion superalloy  

Microsoft Academic Search

The resistance to stress-accelerated grain boundary oxygen embrittlement (SAGBO) in Fe–Ni–Co–Nb–Ti controlled low expansion superalloy has been improved by trace yttrium element addition. The platelet precipitates in the alloy have been studied by means of optical microscopy, transmission electron microscopy, convergent beam electron microscopy, high-resolution transmission electron microscopy and X-ray diffraction technique. The crystal structure and the chemical composition of

R. M. Wang; C. Z. Li; D. H. Ping; M. G. Yan

1998-01-01

272

Study on phosphating treatment of aluminum alloy: role of yttrium oxide  

Microsoft Academic Search

Zinc phosphate coatings formed on 6061-Al alloy, after dipping in phosphating solutions containing different amounts of Y2O3(yttrium oxide), were studied by scanning electron microscopy (SEM), X-ray diffraction (XRD) and electrochemical measurements. Significant variations in the morphology and corrosion resistance afforded by zinc phosphate coating were especially observed as Y2O3 in phosphating solution varied from 0 to 40 mg\\/L. The addition

Shenglin ZHANG

2009-01-01

273

Spin wave localization in one-dimensional magnonic microcavity comprising yttrium iron garnet  

NASA Astrophysics Data System (ADS)

We demonstrate the localization of magnetostatic surface waves, i.e., spin waves, in a one-dimensional magnonic microcavity substantialized with periodical conductivity modulation. The narrow localized state is observed inside band gaps and is responsible for a sharp transmission peak. The experimental results strongly agree with the theoretical prediction made with the shape magnetic anisotropy of the propagating medium composed of yttrium iron garnet taken into account.

Kanazawa, Naoki; Goto, Taichi; Inoue, Mitsuteru

2014-08-01

274

PLASTICIT DU SESQUIOXYDE D'YTTRIUM (Y2O3) PAR MICRO-INDENTATION  

E-print Network

oxydes [2], lui confère une grande stabilité par rapport à la température. C'est un des oxydes les moins contexte de l'étude des propriétés plas- tiques de cet oxyde, que ce travail est effectué. 2. Echantillons d'oxyde d'yttrium. - La structure de Y2O3 peut être obtenue à partir de la structure fluorine (CaF2

Paris-Sud XI, Université de

275

Effect of nonstoichiometry on fracture toughness and hardness of yttrium oxide ceramics  

Microsoft Academic Search

This work deals with the changes in mechanical properties of yttrium oxide ceramics induced by nonstoichiometry. The maximum fracture toughness Î\\/sub ic\\/, is observed at the stoichiometric composition. For an oxygen-deficient ceramic, a decrease of Î\\/sub ic\\/ is observed from 3.5 to 2.3 MPa.m¹². On the other hand, the Vickers hardness seems to be less dependent on stoichiometry. These results

Gilbert Fantozzi; Gilles Orange; Kaiming Liang; Martine Gautier; Jean-Paul Duraud; Philippe Maire; C. LeGressus; E. Gillett

1989-01-01

276

Superselective Internal Radiation With Yttrium-90 Microspheres in the Management of a Chemorefractory Testicular Liver Metastasis  

SciTech Connect

We treated a patient with biopsy-proven, chemotherapy-resistant testicular cancer liver metastasis using Y-90 selective internal radiation treatment. We chose yttrium-90 rather than surgery and ablation due to tumor location and size as well as the patient's clinical history. The result was marked tumor response by positron emission tomography and computed tomography as well as significant improvement of the patient's quality of life accompanied by a substantial decrease of his tumor markers.

Sideras, Panagiotis A.; Sofocleous, Constantinos T., E-mail: sofoclec@mskcc.org; Brody, Lynn A.; Siegelbaum, Robert H.; Shah, Rajesh P.; Taskar, Neeta-Pandit [Memorial Sloan Kettering Cancer Center (United States)

2012-04-15

277

Correlations of the Stability, Static Dipole Polarizabilities, and Electronic Properties of Yttrium Clusters  

Microsoft Academic Search

Static dipole polarizabilities for the ground-state geometries of yttrium clusters (Yn, n <= 15) are investigated by using the numerically finite field method in the framework of density functional theory. The structural size dependence of electronic properties, such as the highest occupied molecular orbital-lowest occupied molecular orbital (HOMO-LUMO) gap, ionization energy, electron affinity, chemical hardness and softness, etc., has been

Xi-Bo Li; Hong-Yan Wang; Ran Lv; Wei-Dong Wu; Jiang-Shan Luo; Yong-Jian Tang

2009-01-01

278

Erbium, chromium:yttrium–scandium–gallium–garnet laser-assisted sinus graft procedure  

Microsoft Academic Search

The possibility of using lasers in the field of dentistry has been a subject of investigation. There are few reports that\\u000a any laser systems have been used for bony window osteotomy by direct sinus grafting. In this study, erbium, chromium:yttrium–scandium–gallium–garnet\\u000a (Er,Cr:YSGG) laser of various laser systems was used for 12 sinus bone grafts in ten patients, and the efficiency of

Dong-Seok Sohn; Ji-Soo Lee; Kyung-Mi An; George E. Romanos

2009-01-01

279

Evaluation of mineral content of dentin prepared by erbium, chromium:yttrium scandium gallium garnet laser  

Microsoft Academic Search

Laser etching has an effect on the mineral content of dentin. The aim of this study was to evaluate the mineral content of\\u000a dentin prepared at three different power settings with an erbium, chromium:yttrium scandium gallium garnet (Er,Cr:YSGG) laser.\\u000a The enamel of five, lower, wisdom, molar teeth was removed to expose the dentin surface. Four dentin slabs were obtained,\\u000a then

Asli Secilmis; Subutayhan Altintas; Aslihan Usumez; Gizem Berk

2008-01-01

280

Shear bond strength of composite bonded to erbium:yttrium-aluminum-garnet laser-prepared dentin  

Microsoft Academic Search

The purpose of this study was to evaluate the dentin bond strength to resin composite following erbium:yttrium-aluminum-garnet\\u000a (Er:YAG) laser preparation using different adhesive systems. Seventy dentin specimens prepared from human molar teeth were\\u000a randomly assigned to seven groups of ten. The first five groups were prepared with an Er:YAG laser 2940 nm at the manufacturer’s\\u000a recommended settings and (1) acid etched,

Sevil Gurgan; Arlin Kiremitci; Filiz Yalcin Cakir; Esra Yazici; Jale Gorucu; Norbert Gutknecht

2009-01-01

281

Hydrothermal synthesis, crystal structures and photoluminescence properties of mixed europium-yttrium organic frameworks  

SciTech Connect

Three mixed europium-yttrium organic frameworks: Eu{sub 2-x}Y{sub x}(Mel)(H{sub 2}O){sub 6} (Mel=mellitic acid or benzene-1,2,3,4,5,6-hexacarboxylic acid, x=0.38 1, 0.74 2, and 0.86 3) have been synthesized and characterized. All the compounds contain a 3-D net with (4, 8)-flu topology. The study indicates that the photoluminescence properties are effectively affected by the different ratios of europium and yttrium ions, the quantum efficiency is increased and the Eu{sup 3+} lifetime becomes longer in these MOFs than those of the Eu analog. - Graphical abstract: Three mixed europium and yttrium organic frameworks: Eu{sub 2-x}Y{sub x}(Mel)(H{sub 2}O){sub 6} (Mel=mellitic acid) have been synthesized and characterized. All the compounds contain a 3-D net with (4, 8)-flu topology. The study indicates that the photoluminescence properties are effectively affected by the different ratios of europium and yttrium ions, the quantum efficiency is increased and the Eu{sup 3+} lifetime becomes longer in these MOFs than those of the Eu analog. Highlights: Black-Right-Pointing-Pointer Three (4, 8)-flu topological mixed Eu and Y MOFs were synthesized under mild conditions. Black-Right-Pointing-Pointer Metal ratios were refined by the single crystal data consistent with the EDS analysis. Black-Right-Pointing-Pointer Mixed Eu and Y MOFs show longer lifetime and higher quantum efficiency than the Eu analog. Black-Right-Pointing-Pointer Adding inert lanthanide into luminescent MOFs enlarges the field of luminescent MOFs.

Han Yinfeng [Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro (Portugal); Department of Chemistry and Environmental Science, Taishan University, Taian 271021 (China); Fu Lianshe [Department of Physics, CICECO, University of Aveiro, 3810-193 Aveiro (Portugal); Mafra, Luis, E-mail: lmafra@ua.pt [Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro (Portugal); Shi, Fa-Nian, E-mail: fshi@ua.pt [Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro (Portugal)

2012-02-15

282

Efficient holmium:yttrium lithium fluoride laser longitudinally pumped by a semiconductor laser array  

NASA Technical Reports Server (NTRS)

Optical pumping of a holmium:yttrium lithium floride (Ho:YLF) crystal with a 790-nm continuous-wave diode-laser array has generated 56 mW of 2.1-micron laser radiation with an optical-to-optical conversion slope efficiency of 33 percent while the crystal temperature is held at 77 K. The lasing threshold occurs at 7 mW of input power, and laser operation continues up to a crystal temperature of 124 K.

Hemmati, H.

1987-01-01

283

Peripheral Blood Lymphocyte Depletion After Hepatic Arterial {sup 90}Yttrium Microsphere Therapy for Hepatocellular Carcinoma  

SciTech Connect

Purpose: The short- and long-term effects of {sup 90}Yttrium microspheres therapy for hepatocellular carcinoma (HCC) on peripheral blood lymphocytes are unknown and were therefore examined. Methods and Materials: Ninety-two HCC patients were enrolled in a {sup 90}Yttrium therapy study and routine blood counts were examined as part of standard clinical monitoring. Results: We found an early, profound, and prolonged lymphopenia. In a subsequent cohort of 25 additional HCC patients, prospective flow cytometric immune-monitoring analysis was performed to identify specific changes on distinct lymphocyte subsets (i.e., CD3, CD4, CD8 T, and CD19 B lymphocytes) and NK cells absolute numbers, in addition to the granulocytes and platelets subsets. We found that the pretreatment lymphocyte subset absolute numbers (with the exception of NK cells) had a tendency to be lower compared with healthy control values, but no significant differences were detected between groups. Posttherapy follow-up revealed that overall, all lymphocyte subsets, except for NK cells, were significantly (>50% from pretherapy values), promptly (as early as 24 h) and persistently (up to 30 months) depleted post-{sup 90}Yttrium microspheres therapy. In contrast, granulocytes increased rapidly (24 h) to compensate for lymphocyte depletion, and remained increased at 1-year after therapy. We further stratified patients into two groups, according to survival at 1 year. We found that lack of recovery of CD19, CD3, CD8, and especially CD4 T cells was linked to poor patient survival. No fungal or bacterial infections were noted during the 30-month follow-up period. Conclusions: The results show that lymphocytes (and not granulocytes, platelets, or NK cells) are sensitive to hepatic arterial {sup 90}Yttrium without associated clinical toxicity, and lack of lymphocyte recovery (possibly leading to dysregulation of adaptive cellular immunity) posttherapy indicates poor survival.

Carr, Brian I., E-mail: brianicarr@hotmail.com [Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA and Department of Nutrition and Exptl Biology, Saverio De Bellis Medical Research Institute, Castellana Grotte, Bari (Italy); Metes, Diana M. [Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA and Department of Nutrition and Exptl Biology, Saverio De Bellis Medical Research Institute, Castellana Grotte, Bari (Italy)

2012-03-01

284

Recovery of niobium from irradiated targets  

DOEpatents

A process for selective separation of niobium from proton irradiated molybdenum targets is provided and includes dissolving the molybdenum target in a hydrogen peroxide solution to form a first ion-containing solution, contacting the first ion-containing solution with a cationic resin whereby ions selected form the group consisting of molybdenum, biobium, technetium, selenium, vanadium, arsenic, germanium, zirconium and rubidium remain in a second ion-containing solution while ions selected from the group consisting of rubidium, zinc, beryllium, cobalt, iron, manganese, chromium, strontium, yttrium and zirconium are selectively adsorbed by the cationic resin; adjusting the pH of the second ion-containing solution to within a range of from about 5.0 to about 6.0; contacting the pH adjusting second ion-containing solution with a dextran-based material for a time to selectively separate niobium from the solution and recovering the niobium from the dextran-based material.

Phillips, Dennis R. (Los Alamos, NM); Jamriska, Sr., David J. (Los Alamos, NM); Hamilton, Virginia T. (Los Alamos, NM)

1994-01-01

285

Spectroscopy of 88Y by the (p,d ) Reaction  

SciTech Connect

Low-spin, high-excitation energy states in 88Y have been studied using the 89Y(p,d ) reaction. For this experiment a 25 MeV proton beam was incident upon a monoisotopic 89Y target. A silicon telescope array was used to detect deuterons, and coincident rays were detected using a germanium clover array. Most of the known low-excitation-energy low-spin states populated strongly via the (p, d) reaction mechanism are confirmed. Two states are seen for the first time and seven new transitions, including one which bypasses the two low-lying isomeric states, are observed.

Ross, T.J. [University of Richmond; Beausang, C.W. [University of Richmond; Hughes, R.O. [University of Richmond; Scielzo, N.D. [Lawrence Livermore National Laboratory (LLNL); Burke, J.T. [Lawrence Livermore National Laboratory (LLNL); Allmond, James M [ORNL; Angell, C.T. [Lawrence Berkeley National Laboratory (LBNL); Basunia, M.S. [Lawrence Berkeley National Laboratory (LBNL); Bleuel, D.L. [Lawrence Livermore National Laboratory (LLNL); Casperson, R.J. [Lawrence Livermore National Laboratory (LLNL); Escher, J.E. [Lawrence Livermore National Laboratory (LLNL); Fallon, P. [Lawrence Berkeley National Laboratory (LBNL); Hatarik, R. [Lawrence Berkeley National Laboratory (LBNL); Munson, J. [Lawrence Berkeley National Laboratory (LBNL); Paschalis, S. [Lawrence Berkeley National Laboratory (LBNL); Petri, M. [Lawrence Berkeley National Laboratory (LBNL); Phair, L. [Lawrence Berkeley National Laboratory (LBNL); Ressler, J.J. [Lawrence Livermore National Laboratory (LLNL)

2012-01-01

286

Applications of an Y88/Be Photoneutron Calibration Source to Dark Matter and Neutrino Experiments  

NASA Astrophysics Data System (ADS)

The low-energy monochromatic neutron emission from an Y88/Be source can be exploited to mimic the few keVnr nuclear recoils expected from low-mass weakly interacting massive particles and coherent scattering of neutrinos off nuclei. Using this source, a ?10% quenching factor is measured for sodium recoils below 24keVnr in NaI[Tl]. This is considerably smaller than the 30% typically adopted in the interpretation of the DAMA/LIBRA dark matter experiment, resulting in a marked increase of its tension with other searches, under the standard set of phenomenological assumptions. The method is illustrated for other target materials (superheated and noble liquids).

Collar, J. I.

2013-05-01

287

The influence of implanted yttrium on the cyclic oxidation behaviour of 304 stainless steel  

NASA Astrophysics Data System (ADS)

High-temperature alloys are frequently used in power plants, gasification systems, petrochemical industry, combustion processes and in aerospace applications. Depending on the application, materials are subjected to corrosive atmospheres and thermal cycling. In the present work, thermal cycling was carried out in order to study the influence of implanted yttrium on the oxide scale adherence on 304 steel specimens oxidised in air at 1273 K. In situ X-ray diffraction indicates that the oxides formed at 1273 K are different on blank specimens compared to implanted specimens. Glancing angle XRD allows to analyse the oxide scale composition after cooling to room temperature. Experimental results show that yttrium implantation at a nominal dose of 10 17 ions cm -2 does not improve significantly the cyclic oxidation behaviour of the austenitic AISI 304 steel. However, it appears that yttrium implantation remarkably enhance the oxidation resistance during isothermal oxidation. It reduces the transient oxidation stage and the parabolic oxidation rate constant by one order of magnitude.

Riffard, F.; Buscail, H.; Caudron, E.; Cueff, R.; Issartel, C.; Perrier, S.

2006-03-01

288

Novel syntergistic agent for selective separation of yttrium from other rare earth metals  

SciTech Connect

An oil-soluble synergistic agent has been developed for the selective separation of yttrium (Y) from the other rare earth metals. The synergistic agent is a polyaminocarboxylic acid alkylderivative and has interfacial activity like that of surfactants. Separation of yttrium from heavy rare earth metals (erbium (Er) and holmium (Ho)) in the presence of the synergistic agent was carried out with a 2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester as a carrier using a hollow-fiber membrane extractor. The new agent shows a synergistic effect on the permeation rate of rare earth metals at the oil-water interface. By the addition of a small amount of the agent, the selectivity for yttrium from the two rare earth metals was enhanced remarkably, because of the permeation rate of Y was selectively decreased compared with those of Er and Ho. The synergistic effect is discussed from the viewpoint of the stability constant for rare earth metals and the interfacial activity of the synergistic agent. The difference in interaction between the synergistic agent and rare earth ions at the oil-water interface results in an increase in the separation efficiency.

Miyata, Terufumi; Goto, Masahiro; Nakashio, Fumiyuki [Kyushu Univ., Fukuoka (Japan)

1995-06-01

289

Yttrium-90 microspheres for the treatment of hepatocellular carcinoma: A review  

SciTech Connect

To present a critical review of yttrium-90 (TheraSphere) for the treatment of hepatocellular carcinoma (HCC). Medical literature databases (Medline, Cochrane Library, and CANCERLIT) were searched for available literature concerning the treatment of HCC with TheraSphere. These publications were reviewed for scientific and clinical validity. Studies pertaining to the use of yttrium-90 for HCC date back to the 1960s. The results from the early animal safety studies established a radiation exposure range of 50-100 Gy to be used in human studies. Phase I dose escalation studies followed, which were instrumental in delineating radiation dosimetry and safety parameters in humans. These early studies emphasized the importance of differential arteriolar density between hypervascular HCC and surrounding liver parenchyma. Current trends in research have focused on advancing techniques to safely implement this technology as an alternative to traditional methods of treating unresectable HCC, such as external beam radiotherapy, conformal beam radiotherapy, ethanol ablation, trans-arterial chemoembolization, and radiofrequency ablation. Yttrium-90 (TheraSphere) is an outpatient treatment option for HCC. Current and future research should focus on implementing multicenter phase II and III trials comparing TheraSphere with other therapies for HCC.

Salem, Riad [Radiology, Section of Interventional Radiology, Northwestern Memorial Hospital, Chicago, IL (United States)]. E-mail: r-salem@northwestern.edu; Hunter, Russell D. [MDS Pharma Services, Global Clinical Development, King of Prussia, PA (United States)

2006-10-01

290

Polymorphism in yttrium molybdate Y{sub 2}Mo{sub 3}O{sub 12}  

SciTech Connect

Yttrium molybdate (Y{sub 2}Mo{sub 3}O{sub 12}) has been prepared by non-hydrolytic sol-gel chemistry. The phase evolution upon heating was investigated using in situ and ex situ heat treatments combined with powder X-ray diffraction. This method has led to the isolation of two orthorhombic phases with different atomic connectivity. Yttrium adopts 6- and 7-coordinate sites in the Pbcn and Pba2 structures, respectively. Cocrystallization of both phases was observed in a narrow temperature range, suggesting that crystallization kinetics play a major role in phase formation. It was found that the Pba2 phase is the stable polymorph below 550 deg. C, and converts to Pbcn at higher temperatures. - Graphical abstract: Yttrium molybdate (Y{sub 2}Mo{sub 3}O{sub 12}) prepared by non-hydrolytic sol-gel chemistry crystallizes in a mixture of orthorhombic polymorphs with different atomic connectivities. The Pbcn and Pba2 phases coexist over a narrow temperature range. Crystallization of the Pbcn structure is kinetically favored. The Pba2 polymorph is the thermodynamically stable phase at low temperatures, and converts to Pbcn above 550 deg. C.

Gates, Stacy D. [Department of Chemistry, University of Toledo, Toledo, OH 43606 (United States); Lind, Cora [Department of Chemistry, University of Toledo, Toledo, OH 43606 (United States)], E-mail: cora.lind@utoledo.edu

2007-12-15

291

Cold laser machining of nickel-yttrium stabilised zirconia cermets: Composition dependence  

SciTech Connect

Cold laser micromachining efficiency in nickel-yttrium stabilised zirconia cermets was studied as a function of cermet composition. Nickel oxide-yttrium stabilised zirconia ceramic plates obtained via tape casting technique were machined using 8-25 ns pulses of a Nd: YAG laser at the fixed wavelength of 1.064 {mu}m and a frequency of 1 kHz. The morphology of the holes, etched volume, drill diameter, shape and depth were evaluated as a function of the processing parameters such as pulse irradiance and of the initial composition. The laser drilling mechanism was evaluated in terms of laser-material interaction parameters such as beam absorptivity, material spallation and the impact on the overall process discussed. By varying the nickel oxide content of the composite the optical absorption (-value is greatly modified and significantly affected the drilling efficiency of the green state ceramic substrates and the morphology of the holes. Higher depth values and improved drilled volume upto 0.2 mm{sup 3} per pulse were obtained for substrates with higher optical transparency (lower optical absorption value). In addition, a laser beam self-focussing effect is observed for the compositions with less nickel oxide content. Holes with average diameter from 60 {mu}m to 110 {mu}m and upto 1 mm in depth were drilled with a high rate of 40 ms per hole while the final microstructure of the cermet obtained by reduction of the nickel oxide-yttrium stabilised zirconia composites remained unchanged.

Sola, D. [Instituto de Ciencia de Materiales de Aragon, CSIC- Universidad de Zaragoza, C/ Pedro Cerbuna 12, E-50009, Zaragoza (Spain); Gurauskis, J., E-mail: jonas.gurauskis@unizar.es [Instituto de Ciencia de Materiales de Aragon, CSIC- Universidad de Zaragoza, C/ Pedro Cerbuna 12, E-50009, Zaragoza (Spain); Pena, J.I.; Orera, V.M. [Instituto de Ciencia de Materiales de Aragon, CSIC- Universidad de Zaragoza, C/ Pedro Cerbuna 12, E-50009, Zaragoza (Spain)

2009-09-15

292

Effect of yttrium additions on void swelling in Liquid Metal Fast Breeder Reactor candidate cladding alloys  

SciTech Connect

Candidate Liquid Metal Fast Breeder Reactor cladding alloys AL1 (Fe-26% Ni-9% Cr) and AL2 (Fe-35% Ni-12% Cr) without and with the addition of 0.1% yttrium were bombarded by 4 MeV/sup 56/Fe/sup 2 +/ ions without and with simultaneous bombardment by 0.4 MeV /sup 4/He/sup +/ ions. These bombardments were conducted at various irradiation temperatures to determine the effect of yttrium on void swelling. The addition of yttrium decreased peak swelling for 4 MeV /sup 56/Fe/sup 2 +/ ion bombarded AL1 and AL2 by 28% and 20%, respectively. In all cases where similar sample comparisons were made (i.e., undoped with undoped and doped with doped) and where bombardment conditions were similar (i.e., single with single beam and dual with dual beam), AL1 showed less peak swelling than did AL2. Simultaneously implanting helium during heavy-ion bombardment increased peak swelling in undoped and doped AL1 by factors of 2.3 and 2.6, respectively.

Hopson, R.D.

1981-10-01

293

Space Shuttle Endeavour arrives at Launch Pad 39A for Mission STS-88  

NASA Technical Reports Server (NTRS)

Towering atop the mobile launcher platform and crawler transporter in the early morning light, Space Shuttle Endeavour arrives at Launch Pad 39A after rollout from the Vehicle Assembly Building. At its left are the Rotating Service Structure and the Fixed Service Structure; at the right is the 300,000-gallon water tank, part of the sound suppression water system. While at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-88 launch targeted for Dec. 3, 1998. Mission STS-88 is the first U.S. flight for the assembly of the International Space Station and will carry the Unity connecting module. While on orbit, the flight crew will deploy Unity from the payload bay and connect it to the Russian- built Zarya control module which will be in orbit at that time. Unity will be the main connecting point for later U.S. station modules and components. More than 40 launches are planned over five years involving the resources and expertise of 16 cooperating nations. Comprising the STS-88 crew are Commander Robert D. Cabana, Pilot Frederick W. 'Rick' Sturckow, Mission Specialists Nancy J. Currie, Jerry L. Ross, James H. Newman and Russian cosmonaut Sergei Konstantinovich Krikalev. Ross and Newman will make three spacewalks to connect power, data and utility lines and install exterior equipment.

1998-01-01

294

Space Shuttle Endeavour arrives at Launch Pad 39A for Mission STS-88  

NASA Technical Reports Server (NTRS)

Space Shuttle Endeavour arrives at Launch Pad 39A in the dim early morning light, atop the mobile launcher platform and crawler transporter, after rollout from the Vehicle Assembly Building. The flag identifying the Shuttle (at right) waves slightly from the wind. At left are the Fixed Service Structure and Rotating Service Structure. While at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-88 launch targeted for Dec. 3, 1998. Mission STS-88 is the first U.S. flight for the assembly of the International Space Station and will carry the Unity connecting module. While on orbit, the flight crew will deploy Unity from the payload bay and connect it to the Russian-built Zarya control module which will be in orbit at that time. Unity will be the main connecting point for later U.S. station modules and components. More than 40 launches are planned over five years involving the resources and expertise of 16 cooperating nations. Comprising the STS-88 crew are Commander Robert D. Cabana, Pilot Frederick W. 'Rick' Sturckow, Mission Specialists Nancy J. Currie, Jerry L. Ross, James H. Newman and Russian cosmonaut Sergei Konstantinovich Krikalev. Ross and Newman will make three spacewalks to connect power, data and utility lines and install exterior equipment.

1998-01-01

295

Space Shuttle Endeavour arrives at Launch Pad 39A for Mission STS-88  

NASA Technical Reports Server (NTRS)

In the cloud-dimmed light of early morning, Space Shuttle Endeavour sits in place at Launch Pad 39A , atop the mobile launcher platform and crawler transporter, after rollout from the Vehicle Assembly Building. At its left are the Rotating Service Structure and Fixed Service Structure with the orbiter access arm extended. The access arm swings out to the orbiter crew compartment hatch to allow personnel to enter the crew compartment. At its outer end is the white room, an environmental chamber, that mates with the orbiter. While at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-88 launch targeted for Dec. 3, 1998. Mission STS-88 is the first U.S. flight for the assembly of the International Space Station and will carry the Unity connecting module. While on orbit, the flight crew will deploy Unity from the payload bay and connect it to the Russian-built Zarya control module which will be in orbit at that time. Unity will be the main connecting point for later U.S. station modules and components. More than 40 launches are planned over five years involving the resources and expertise of 16 cooperating nations. Comprising the STS-88 crew are Commander Robert D. Cabana, Pilot Frederick W. 'Rick' Sturckow, Mission Specialists Nancy J. Currie, Jerry L. Ross, James H. Newman and Russian cosmonaut Sergei Konstantinovich Krikalev. Ross and Newman will make three spacewalks to connect power, data and utility lines and install exterior equipment.

1998-01-01

296

Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses.  

PubMed

Intestinal epithelial cells (IECs), including secretory goblet cells, form essential physiochemical barriers that separate luminal bacteria from underlying immune cells in the intestinal mucosa. IECs are common targets for enteric bacterial pathogens, with hosts responding to these microbes through innate toll-like receptors that predominantly signal through the MyD88 adaptor protein. In fact, MyD88 signaling confers protection against several enteric bacterial pathogens, including Salmonella enterica serovar Typhimurium and Citrobacter rodentium. Since IECs are considered innately hyporesponsive, it is unclear whether MyD88 signaling within IECs contributes to this protection. We infected mice lacking MyD88 solely in their IECs (IEC-Myd88(-/-)) with S. Typhimurium. Compared to wild-type (WT) mice, infected IEC-Myd88(-/-) mice suffered accelerated tissue damage, exaggerated barrier disruption, and impaired goblet cell responses (Muc2 and RELM?). Immunostaining revealed S. Typhimurium penetrated the IECs of IEC-Myd88(-/-) mice, unlike in WT mice, where they were sequestered to the lumen. When isolated crypts were assayed for their antimicrobial actions, crypts from IEC-Myd88(-/-) mice were severely impaired in their antimicrobial activity against S. Typhimurium. We also examined whether MyD88 signaling in IECs impacted host defense against C. rodentium, with IEC-Myd88(-/-) mice again suffering exaggerated tissue damage, impaired goblet cell responses, and reduced antimicrobial activity against C. rodentium. These results demonstrate that MyD88 signaling within IECs plays an important protective role at early stages of infection, influencing host susceptibility to infection by controlling the ability of the pathogen to reach and survive at the intestinal mucosal surface. PMID:24958710

Bhinder, Ganive; Stahl, Martin; Sham, Ho Pan; Crowley, Shauna M; Morampudi, Vijay; Dalwadi, Udit; Ma, Caixia; Jacobson, Kevan; Vallance, Bruce A

2014-09-01

297

PI-88 and novel heparan sulfate mimetics inhibit angiogenesis.  

PubMed

The heparan sulfate (HS) mimetic PI-88 is a promising inhibitor of tumor growth and metastasis expected to commence phase III clinical evaluation in 2007 as an adjuvant therapy for postresection hepatocellular carcinoma. Its anticancer properties are attributed to inhibition of angiogenesis via antagonism of the interactions of angiogenic growth factors and their receptors with HS. It is also a potent inhibitor of heparanase, an enzyme that plays a key role in both metastasis and angiogenesis. A series of PI-88 analogs have been prepared with enhanced chemical and biological properties. The new compounds consist of single, defined oligosaccharides with specific modifications designed to improve their pharmacokinetic properties. These analogs all inhibit heparanase and bind to the angiogenic fibroblast growth factor 1 (FGF-1), FGF-2, and vascular endothelial growth factor with similar affinity to PI-88. However, compared with PI-88, some of the newly designed compounds are more potent inhibitors of growth factor-induced endothelial cell proliferation and of endothelial tube formation on Matrigel. Representative compounds were also tested for antiangiogenic activity in vivo and were found to reduce significantly blood vessel formation. Moreover, the pharmacokinetic profile of several analogs was also improved, as evidenced primarily by lower clearance in comparison with PI-88. The current data support the development of HS mimetics as potent antiangiogenic anticancer agents. PMID:17629854

Ferro, Vito; Dredge, Keith; Liu, Ligong; Hammond, Edward; Bytheway, Ian; Li, Caiping; Johnstone, Ken; Karoli, Tomislav; Davis, Kat; Copeman, Elizabeth; Gautam, Anand

2007-07-01

298

A Study of the Density of Unfilled States in Yttrium Barium Copper Oxide by means of Soft X-ray Continuum Isochromats  

NASA Astrophysics Data System (ADS)

The New Mexico State University two-crystal X-ray spectrometer is designed for spectroscopy in the soft X-ray region. It has a demountable ultra-high vacuum X-ray tube and is equipped with Potassium Acid Phthalate (KAP) crystals and a flowing gas proportional counter. The KAP crystals provide a unique and sensitive spectral window at a photon energy of 530 eV. The high signal to background available makes it possible to record continuum limit spectra as continuum isochromats. We intend to obtain continuum isochromats at 530 eV from Yttrium Barium Copper Oxide, a high temperature superconductor. Such spectra are convolutions of the energy spectrum of the incident electrons in the target with the product of the density of unfilled states and a matrix element for the transition. The spectrum of initially mono-energetic electrons in the target can be derived from equivalent photoemission experiments and used to obtain a representation of the density of unfilled states above the Fermi level of the target material from the isochromat spectra.

Rajaram, Ramya; Liefeld, Robert

2002-10-01

299

Use of CAP88 at Department of Energy Sites  

SciTech Connect

The U.S. Department of Energy is committed to protecting the public and environment against undue risk from radiation associated with radiological activities conducted under its control. Some U.S. Department of Energy Site activities result in emissions of radioactive materials to the air. CAP88 codes are used to model these emissions and the subsequent maximum estimated dose to a member of the public in the vicinity of the U.S. Department of Energy Site. This paper reviews the use of the CAP88 code at the variety of U.S. Department of Energy sites that use it for compliance reporting under 40 CFR Part 61, Subpart H.

Snyder, Sandra F.; Vazquez, Gustavo; Hay, Tristan R.

2013-08-16

300

9 CFR 3.88 - Primary conveyances (motor vehicle, rail, air, and marine).  

...2014-01-01 false Primary conveyances (motor vehicle, rail, air, and marine). 3.88 Section 3.88 Animals and...Standards § 3.88 Primary conveyances (motor vehicle, rail, air, and marine). (a) The animal cargo space...

2014-01-01

301

[Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted] Domestic Production and Use: Rare earths were mined by one U.S. company in 2012. Bastnasite, a rare-earth  

E-print Network

184 YTTRIUM1 [Data in metric tons of yttrium oxide (Y2O3) content unless otherwise noted] Domestic-temperature superconductors, and superalloys. The approximate distribution in 2012 by end use was as follows: phosphors, 44 Yttrium oxide, per kilogram, minimum 99.9% purity 5 10­85 10­85 38­41 165­185 90-110 Yttrium metal, per

302

Novel myeloid differentiation factor 88, EsMyD88, exhibits EsTube-binding activity in Chinese mitten crab Eriocheir sinensis.  

PubMed

Myeloid differentiation factor 88 (MyD88) is a universal and essential adapter protein that participates in the activation of the Toll-like receptor/interleukin-1 receptor-mediated signaling pathway. In the present study, a new MyD88 gene (named EsMyD88) was identified in the Chinese mitten crab Eriocheir sinensis. The cDNA of EsMyD88 was 2210?bp long with a 1416?bp open reading frame that encoded a protein with 472 amino acids. Predicted EsMyD88 protein had a death domain at the N-terminal and a TIR domain at the C-terminal. BLASTP and phylogenetic analysis results showed that EsMyD88 was clustered in one group together with other crustaceans MyD88 (SpMyD88, FcMyD88, LvMyD88, and LvMyD88-1). EsMyD88 was detected in all the examined tissues of healthy crabs, and was mainly expressed in the hemocytes and nerves. When normal crabs were challenged with lipopolysaccharide, peptidoglycan, Staphylococcus aureus, Vibrio parahaemolyticus, or Aeromonas hydrophila, the expression levels of EsMyD88 significantly increased either in the hepatopancreas or hemocytes. Results of the pull-down assay showed that EsMyD88 could bind to downstream cytosolic adaptor EsTube. Overexpression of EsMyD88 protein in Drosophila Schneider 2 cells led to the activation of antimicrobial peptide genes. RNA interference assay showed that EsMyD88 is involved in regulating the transcription of ALF1 and ALF2, Cru1 and Cru2, and Lys in crab challenged with V. parahaemolyticus. All the results mentioned earlier indicated that EsMyD88 gene has a key function in antibacterial innate immune defense. PMID:25150191

Huang, Ying; Chen, Yi-Hong; Wang, Zheng; Wang, Wen; Ren, Qian

2014-12-01

303

Model-Based Radiation Dose Correction for Yttrium-90 Microsphere Treatment of Liver Tumors With Central Necrosis  

SciTech Connect

Purpose: The objectives of this study were to model and calculate the absorbed fraction {phi} of energy emitted from yttrium-90 ({sup 90}Y) microsphere treatment of necrotic liver tumors. Methods and Materials: The tumor necrosis model was proposed for the calculation of {phi} over the spherical shell region. Two approaches, the semianalytic method and the probabilistic method, were adopted. In the former method, the range--energy relationship and the sampling of electron paths were applied to calculate the energy deposition within the target region, using the straight-ahead and continuous-slowing-down approximation (CSDA) method. In the latter method, the Monte Carlo PENELOPE code was used to verify results from the first method. Results: The fraction of energy, {phi}, absorbed from {sup 90}Y by 1-cm thickness of tumor shell from microsphere distribution by CSDA with complete beta spectrum was 0.832 {+-} 0.001 and 0.833 {+-} 0.001 for smaller (r{sub T} = 5 cm) and larger (r{sub T} = 10 cm) tumors (where r is the radii of the tumor [T] and necrosis [N]). The fraction absorbed depended mainly on the thickness of the tumor necrosis configuration, rather than on tumor necrosis size. The maximal absorbed fraction {phi} that occurred in tumors without central necrosis for each size of tumor was different: 0.950 {+-} 0.000, and 0.975 {+-} 0.000 for smaller (r{sub T} = 5 cm) and larger (r{sub T} = 10 cm) tumors, respectively (p < 0.0001). Conclusions: The tumor necrosis model was developed for dose calculation of {sup 90}Y microsphere treatment of hepatic tumors with central necrosis. With this model, important information is provided regarding the absorbed fraction applicable to clinical {sup 90}Y microsphere treatment.

Liu, Ching-Sheng [National PET/Cyclotron Center, Taipei Veterans General Hospital, Taipei, Taiwan (China); Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan (China); Lin, Ko-Han [Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan (China); Lee, Rheun-Chuan, E-mail: rclee@vghtpe.gov.tw [Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan (China); Tseng, Hsiou-Shan [Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan (China); Wang, Ling-Wei; Huang, Pin-I; Chao, Liung-Sheau [Cancer Therapy Center, Taipei Veterans General Hospital, Taipei, Taiwan (China); Chang, Cheng-Yen [Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan (China); Yen, Sang-Hue [Cancer Therapy Center, Taipei Veterans General Hospital, Taipei, Taiwan (China); Tung, Chuan-Jong [Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan (China); Wang, Syh-Jen [National PET/Cyclotron Center, Taipei Veterans General Hospital, Taipei, Taiwan (China); Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan (China); Oliver Wong, Ching-yee [Department of Nuclear Medicine and PET/Cyclotron Center, Oakland University William Beaumont School of Medicine Hospital, Royal Oak, Michigan (United States); Liu, Ren-Shyan [National PET/Cyclotron Center, Taipei Veterans General Hospital, Taipei, Taiwan (China); Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan (China)

2011-11-01

304

Depletion, Quantum Jumps, and Temperature Measurements of 88  

E-print Network

in Iodine to stabilize the length of a Fabry-Perot cavity for laser locking. After constructing this laser in Physics Abstract This thesis describes the design and construction of two laser systems to probe the 674nm transition of 88 Sr+ ions in a linear Paul trap. The first laser system made use of a molecular transition

Richerme, Phil

305

PHYSICAL REVIEW E 88, 032914 (2013) Weakly noisy chaotic scattering  

E-print Network

PHYSICAL REVIEW E 88, 032914 (2013) Weakly noisy chaotic scattering Juan D. Bernal,* Jes´us M 23 September 2013) The effect of a weak source of noise on the chaotic scattering is relevant affects both the dynamics and the topology of a paradigmatic chaotic scattering problem as the one taking

Rey Juan Carlos, Universidad

306

38 CFR 11.88 - Cancellation of note.  

Code of Federal Regulations, 2010 CFR

...Disposition of Notes Secured by Adjusted Certificates Redeemed from Banks by the Department of Veterans Affairs Under Section 502 of the World War Adjusted Compensation Act, As Amended (pub. L. 120, 68th Cong.) § 11.88 Cancellation of note. When a...

2010-07-01

307

88. MECHANICAL EQUIPMENT ROOM (101), LSB (BLDG. 770). FEATURES LEFT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. MECHANICAL EQUIPMENT ROOM (101), LSB (BLDG. 770). FEATURES LEFT TO RIGHT: S-2 SUPPLY FAN TO BOOSTER POD, R-4 COMPRESSOR, S-4 SUPPLY FAN TO PAYLOAD (SYSTEM 1). - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

308

40 CFR 745.88 - Recognized test kits.  

Code of Federal Regulations, 2010 CFR

40 Protection of Environment 30 2010-07-01 2010-07-01...Section 745.88 Protection of Environment ENVIRONMENTAL PROTECTION...TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION...criteria. For paint containing lead at or above the regulated...

2010-07-01

309

40 CFR 745.88 - Recognized test kits.  

Code of Federal Regulations, 2012 CFR

40 Protection of Environment 32 2012-07-01 2012-07-01...Section 745.88 Protection of Environment ENVIRONMENTAL PROTECTION...TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION...criteria. For paint containing lead at or above the regulated...

2012-07-01

310

40 CFR 745.88 - Recognized test kits.  

Code of Federal Regulations, 2013 CFR

40 Protection of Environment 32 2013-07-01 2013-07-01...Section 745.88 Protection of Environment ENVIRONMENTAL PROTECTION...TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION...criteria. For paint containing lead at or above the regulated...

2013-07-01

311

40 CFR 745.88 - Recognized test kits.  

Code of Federal Regulations, 2011 CFR

40 Protection of Environment 31 2011-07-01 2011-07-01...Section 745.88 Protection of Environment ENVIRONMENTAL PROTECTION...TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION...criteria. For paint containing lead at or above the regulated...

2011-07-01

312

PHYSICAL REVIEW B 88, 024303 (2013) Tunable active acoustic metamaterials  

E-print Network

PHYSICAL REVIEW B 88, 024303 (2013) Tunable active acoustic metamaterials Bogdan-Ioan Popa,* Lucian July 2013) We describe and demonstrate an architecture for active acoustic metamaterials whose types of unit cells that generate metamaterials in which either the effective density or bulk modulus

Cummer, Steven A.

313

Uniform 8×8 lithium niobate switch arrays  

Microsoft Academic Search

We report the fabrication and characterization of two packaged 8×8 Ti:LiNbO3 switch arrays. The devices, with their polarization-maintaining fiber arrays, exhibit low crosstalk and excellent uniformity in control voltages and insertion loss

Edmond J. Murphy; Carl T. Kemmerer; David T. Moser; Michael R. Serbin; James E. Watson; Paul L. Stoddard

1995-01-01

314

88. Photographic copy of retouched photograph (circa 1918, original print ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. Photographic copy of retouched photograph (circa 1918, original print in Archives, Public Affairs Department, Sears Merchandise Group, Hoffman Estates, Illinois). Photographer unknown. INTERIOR VIEW OF MERCHANDISE BUILDING, SHIPPING COURT, SECOND FLOOR - Sears Roebuck & Company Mail Order Plant, Merchandise Building, 924 South Homan Avenue, Chicago, Cook County, IL

315

The Bronson Settlement Review: Year Four, 1987-88.  

ERIC Educational Resources Information Center

School year 1987-88 marked the mid-point of the seven-year desegregation settlement for the Cincinnati (Ohio) Public Schools. This report presents data from a review of progress that was provided for in the Bronson Settlement Agreement, answers plaintiff questions, and addresses district concerns. The following subjects are discussed: (1) progress…

Evans, Robert W.; Nieman, Ronald W.

316

88. Photocopy of drawing (October 1950 architectural drawing by Stevens ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. Photocopy of drawing (October 1950 architectural drawing by Stevens & Wilkinson, original in possession of Stevens & Wilkinson, Atlanta, Georgia). First floor plan, additions and alterations to Rich's Inc., drawing no. A-3. - Rich's Downtown Department Store, 45 Broad Street, Atlanta, Fulton County, GA

317

Rapport Technique TR/CMGC/03/88  

E-print Network

Rapport Technique TR/CMGC/03/88 QUELQUES RESULTATS DES PREVISIONS COUPLEES DEMETER EFFECTUEES AU CERFACS #12;CERFACS Working Note QUELQUES RESULTATS DES PREVISIONS COUPLEES DEMETER EFFECTUEES AU CERFACS résultats ont été obtenus dans le cadre du projet européen DEMETER (Palmer et al., 2003, voir aussi http://www.ecmwf.int/research/demeter

318

3>K88OOJIQ2> ,, ,, , Ris-M-2741  

E-print Network

- 1. INTRODUCTION In validation studies of models used to simulate transport of radionuclides FOR THE PROGRAM TAMDYN A modelling tool for use on personal computers to simulate environmental transportTf 3>K88OOJIQ2> 1$±)1&KQJ ,, ,, , Risø-M-2741 2 Users Guide for the Program TAMDYN A modelling tool

319

PLANKTON SAMPLERS SPECIAL SCIENTIFIC REPORT: FISHERIES No. 88  

E-print Network

HIGH SPEED PLANKTON SAMPLERS SPECIAL SCIENTIFIC REPORT: FISHERIES No. 88 UNITED STATES DEPARTMENT Se^^rice, Albert M» Day, Director HIGH SPEED PLANKTON SAMPLERS 1» A High Speed Plankton Sampler-metal Plankton Sampler (Model Gulf III) by Jack Wo Gehringer Fishery Research Biologist Gulf Fishery

320

Direct atomic flux measurement of electron-beam evaporated yttrium with a diode-laser-based atomic absorption monitor at 668 nm  

E-print Network

Direct atomic flux measurement of electron-beam evaporated yttrium with a diode-laser-based atomic May 1997 A direct measurement of atomic flux in e-beam evaporated yttrium has been demonstrated with a diode-laser-based atomic absorption AA monitor at 668 nm. Atomic number density and velocity were

Fejer, Martin M.

321

The crucial role of the MyD88 adaptor protein in the inflammatory response induced by Bothrops atrox venom.  

PubMed

Most snake accidents in North Brazil are attributed to Bothrops atrox, a snake species of the Viperidae family whose venom simultaneously induces local and systemic effects in the victims. The former are clinically more important than the latter, as they cause severe tissue lesions associated with strong inflammatory responses. Although several studies have shown that inflammatory mediators are produced in response to B. atrox venom (BaV), there is little information concerning the molecular pathways involved in innate immune system signaling. Myeloid differentiation factor 88 (MyD88) is an adaptor molecule responsible for transmitting intracellular signals from most toll-like receptors (TLRs) after they interact with pathogen-associated molecular patterns (PAMPs) or other stimuli such as endogenous damage-associated molecular patterns (DAMPs). The MyD88-dependent pathway leads to activation of transcription factors, which in turn induce synthesis of inflammatory mediators such as eicosanoids, cytokines and chemokines. The aim of this study was to investigate the involvement of MyD88 on the acute inflammatory response induced by BaV. Wild-type (WT) C57BL/6 mice and MyD88 knockout (MyD88(-/-)) mice were intraperitoneally injected with BaV. Compared to WT mice, MyD88(-/-) animals showed an impaired inflammatory response to BaV, with lower influx of polymorphonuclear and mononuclear cells to the peritoneal cavity. Furthermore, peritoneal leukocytes from BaV-injected MyD88(-/-) mice did not induce COX-2 or LTB4 protein expression and released low concentrations of PGE2. These mice also failed to produce Th1 and Th17 cytokines and CCL-2, but IL-10 levels were similar to those of BaV-injected WT mice. Our results indicate that MyD88 signaling is required for activation of the inflammatory response elicited by BaV, raising the possibility of developing new therapeutic targets to treat Bothrops sp. poisoning. PMID:23474268

Moreira, Vanessa; Teixeira, Catarina; Borges da Silva, Henrique; D'Império Lima, Maria Regina; Dos-Santos, Maria Cristina

2013-06-01

322

Prognostic Value of Myeloid Differentiation Primary Response 88 and Toll-Like Receptor 4 in Breast Cancer Patients  

PubMed Central

Purpose Breast cancer remains a major cause of death in women worldwide, and tumor metastasis is the leading cause of death in breast cancer patients after conventional treatment. Chronic inflammation is often related to the occurrence and growth of various malignancies. This study evaluated the prognosis of breast cancer patients based on contributors to the innate immune response: myeloid differentiation primary response 88 (MyD88) and Toll-like receptor 4 (TLR4). Methods We analyzed data from 205 breast invasive ductal carcinoma (IDC) patients who were treated at the Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, from 2002 to 2006. Overall survival (OS) and disease-free survival (DFS) were compared. Results In total, 152 patients (74.15%) were disease-free without relapse or metastasis, whereas 53 (25.85%) patients developed recurrence or metastasis. A significant positive correlation was observed between MyD88 and TLR4 expression (p<0.001). Patients with high expression were more likely to experience death and recurrence/metastasis events (p<0.05). Patients with low MyD88 or TLR4 expression levels had better DFS and OS than patients with high expression levels (log-rank test: p<0.001). Patients with low MyD88 and TLR4 expression levels had better DFS and OS than patients with high expression levels of either (log-rank test: p<0.001). In a multivariate analysis, high MyD88 expression was an independent predictive factor for decreased DFS (adjusted HR, 3.324; 95% CI, 1.663–6.641; p?=?0.001) and OS (adjusted HR, 4.500; 95% CI, 1.546–13.098; p?=?0.006). Conclusions TLR4-MyD88 signaling pathway activation or MyD88 activation alone may be a risk factor for poor prognosis in breast cancer. Therefore, TLR4-MyD88 signaling pathway activation in tumor biology provides a novel potential target for breast cancer therapy. PMID:25360699

Ling, Hong; Li, Shan; Wu, Jiong; Shao, Zhi-Ming

2014-01-01

323

Synthesis and chemistry of yttrium and lanthanide metal complexes. Progress report, March 15, 1991--March 14, 1992  

SciTech Connect

The objective of this research project is to determine the special features of complexes of yttrium and the lanthanide metals which will allow the design and synthesis of materials with unique chemical, physical, and catalytic properties. Past studies of yttrium and lanthanide metal alkyl and hydride complexes stabilized by cyclopentadienyl co-ligands have shown that a substantial, often singular, organometallic chemistry is available via these metals. More extensive utilization of the chemical opportunities available through yttrium and the lanthanides would be possible, however, if stabilizing ancillary ligand systems less sensitive to oxidation and protonolysis than cyclopentadienides could be developed. Alkoxide ligands are attractive in this regard and our recent research had focused on alkoxides and the special opportunities they can provide to these metals. 6 refs., 10 figs.

Evans, W.J.

1991-09-01

324

The comparison of CAP88-PC version 2.0 versus CAP88-PC version 1.0  

SciTech Connect

40 CFR Part 61 (Subpart H of the NESHAP) requires DOE facilities to use approved sampling procedures, computer models, or other approved procedures when calculating Effective Dose Equivalent (EDE) values to members of the public. Currently version 1.0 of the approved computer model CAP88-PC is used to calculate EDE values. The DOE has upgraded the CAP88-PC software to version 2.0. This version provides simplified data entry, better printing characteristics, the use of a mouse, and other features. The DOE has developed and released version 2.0 for testing and comment. This new software is a WINDOWS based application that offers a new graphical user interface with new utilities for preparing and managing population and weather data, and several new decay chains. The program also allows the user to view results before printing. This document describes a test that confirmed CAP88-PC version 2.0 generates results comparable to the original version of the CAP88-PC program.

Yakubovich, B.A.; Klee, K.O.; Palmer, C.R.; Spotts, P.B.

1997-12-01

325

Radiographic Response to Yttrium-90 Radioembolization in Anterior Versus Posterior Liver Segments  

SciTech Connect

The purpose of our study was to determine if preferential radiographic tumor response occurs in tumors located in posterior versus anterior liver segments following radioembolization with yttrium-90 glass microspheres. One hundred thirty-seven patients with chemorefractory liver metastases of various primaries were treated with yttrium-90 glass microspheres. Of these, a subset analysis was performed on 89 patients who underwent 101 whole-right-lobe infusions to liver segments V, VI, VII, and VIII. Pre- and posttreatment imaging included either triphasic contrast material-enhanced CT or gadolinium-enhanced MRI. Responses to treatment were compared in anterior versus posterior right lobe lesions using both RECIST and WHO criteria. Statistical comparative studies were conducted in 42 patients with both anterior and posterior segment lesions using the paired-sample t-test. Pearson correlation was used to determine the relationship between pretreatment tumor size and posttreatment tumor response. Median administered activity, delivered radiation dose, and treatment volume were 2.3 GBq, 118.2 Gy, and 1,072 cm{sup 3}, respectively. Differences between the pretreatment tumor size of anterior and posterior liver segments were not statistically significant (p = 0.7981). Differences in tumor response between anterior and posterior liver segments were not statistically significant using WHO criteria (p = 0.8557). A statistically significant correlation did not exist between pretreatment tumor size and posttreatment tumor response (r = 0.0554, p = 0.4434). On imaging follow-up using WHO criteria, for anterior and posterior regions of the liver, (1) response rates were 50% (PR = 50%) and 45% (CR = 9%, PR = 36%), and (2) mean changes in tumor size were -41% and -40%. In conclusion, this study did not find evidence of preferential radiographic tumor response in posterior versus anterior liver segments treated with yttrium-90 glass microspheres.

Ibrahim, Saad M.; Lewandowski, Robert J.; Ryu, Robert K.; Sato, Kent T.; Gates, Vanessa L. [Northwestern University, Department of Radiology, Section of Interventional Radiology (United States); Mulcahy, Mary F. [Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Department of Medicine, Division of Hematology and Oncology (United States); Kulik, Laura [Northwestern University, Department of Medicine, Division of Hepatology (United States); Larson, Andrew C. [Northwestern University, Department of Biomedical Engineering (United States); Omary, Reed A.; Salem, Riad, E-mail: r-salem@northwestern.ed [Northwestern University, Department of Radiology, Section of Interventional Radiology (United States)

2008-11-15

326

A human 88-kD membrane glycoprotein (CD36) functions in vitro as a receptor for a cytoadherence ligand on Plasmodium falciparum-infected erythrocytes.  

PubMed Central

Plasmodium falciparum-infected erythrocytes (IE) specifically adhere to vascular endothelium in vivo and to human endothelial cells, some human melanoma cell lines, and human monocytes in vitro. The tissue cell receptor for a ligand on the surface of the infected erythrocytes is an Mr 88,000 glycoprotein (GP88) recognized by the MAb OKM5, which also blocks cytoadherence of IE. Isolated, affinity-purified GP88 (CD36) competitively blocks cytoadherence and when absorbed to plastic surfaces, specifically binds P. falciparum IE. Additionally, monoclonal and polyclonal antibodies to GP88 block cytoadherence to both target cells and immobilized GP88. Binding to GP88 by IE is unaffected by the absence of calcium or the absence of thrombospondin, a putative mediator for cytoadherence of P. falciparum IE. Thus, GP88 (CD36), which has been demonstrated to be the same as platelet glycoprotein IV, interacts directly with P. falciparum IE, presumably via a parasite-induced ligand exposed on the surface of the infected erythrocytes. CD36 is shown to be present on brain endothelium in both individuals without malaria and individuals with cerebral malaria. This would suggest that factors other than just cerebral sequestration of IE play an initiating role in the genesis of cerebral malaria. Images PMID:2474574

Barnwell, J W; Asch, A S; Nachman, R L; Yamaya, M; Aikawa, M; Ingravallo, P

1989-01-01

327

Yttrium ionization scheme development for Ti:Sa laser based RILIS  

NASA Astrophysics Data System (ADS)

Resonant ionization laser ion sources (RILIS) are popular ion sources if intense, radioactive ion beams (RIBs) with minimal isobaric contamination are required. The intensity of the ion beam depends strongly on the applied resonant laser ionization scheme. Based on the all solid state laser system TRIUMF's RILIS (TRILIS) is using, the off-line development towards an efficient ionization scheme for yttrium is presented. Several continuous wavelength scans have been performed to compare different nonresonant ionization schemes and to identify suitable Rydberg or autoionizing states for resonant ionization schemes.

Teigelhöfer, A.; Lassen, J.; Abboud, Z.; Bricault, P.; Heggen, H.; Kunz, P.; Li, R.; Quenzel, T.; Raeder, S.

2013-04-01

328

Bond durability in erbium:yttrium–aluminum–garnet laser-irradiated enamel  

Microsoft Academic Search

This study sought to evaluate the influence of thermocycling and water storage on the microtensile bond strength of composite\\u000a resin bonded to erbium:yttrium–aluminum–garnet (Er:YAG)-irradiated and bur-prepared enamel. Eighty bovine incisors were selected\\u000a and sectioned. Specimens were ground to produce a flat enamel surface. Samples were randomly assigned according to cavity\\u000a preparation device: (I) Er:YAG laser and (II) high-speed turbine, and

F. L. B. Amaral; V. Colucci; A. E. Souza-Gabriel; M. A. Chinelatti; R. G. Palma-Dibb; S. A. M. Corona

2010-01-01

329

Improvement of the yttrium iron garnet/platinum interface for spin pumping-based applications  

NASA Astrophysics Data System (ADS)

The dependence of the spin pumping efficiency and the spin mixing conductance on the surface processing of yttrium iron garnet (YIG) before the platinum (Pt) deposition has been investigated quantitatively. The ferromagnetic resonance driven spin pumping injects a spin polarized current into the Pt layer, which is transformed into an electromotive force by the inverse spin Hall effect. Our experiments show that the spin pumping effect indeed strongly depends on the YIG/Pt interface condition. We measure an enhancement of the inverse spin Hall voltage and the spin mixing conductance by more than two orders of magnitude with improved sample preparation.

Jungfleisch, M. B.; Lauer, V.; Neb, R.; Chumak, A. V.; Hillebrands, B.

2013-07-01

330

Thermal Synthesis of Bismuth-Doped Yttrium Iron Garnet for Magneto-Optical Imaging  

NASA Astrophysics Data System (ADS)

This contribution deals with the preparation and characterization of bismuth-doped yttrium iron garnets with composition BiY2Fe5O12 (Bi:YIG). The samples have been prepared by sintering of metal oxides homogenized in acetone for 10 minutes. The estimated average crystallite size of the single phase Bi:YIG synthesized at temperature 950 °C for 15 hours is ~ 65 nm. The real content of Bi3+ cations in samples was quantitatively evaluated by application of real-coded genetic algorithm to the powder X-ray diffraction patterns.

Pigošová, J.; Cigá?, A.; Ma?ka, J.

2008-01-01

331

Spin mixing conductance at a well-controlled platinum/yttrium iron garnet interface  

NASA Astrophysics Data System (ADS)

A platinum (Pt)/yttrium iron garnet (YIG) bilayer system with a well-controlled interface has been developed; spin mixing conductance at the Pt/YIG interface has been studied. A clear interface with good crystal perfection is experimentally demonstrated to be one of the important factors for an ultimate spin mixing conductance. The spin mixing conductance is obtained to be 1.3 × 1018 m-2 at the well-controlled Pt/YIG interface, which is close to a theoretical prediction.

Qiu, Z.; Ando, K.; Uchida, K.; Kajiwara, Y.; Takahashi, R.; Nakayama, H.; An, T.; Fujikawa, Y.; Saitoh, E.

2013-08-01

332

Enhanced spin pumping damping in yttrium iron garnet/Pt bilayers  

NASA Astrophysics Data System (ADS)

Detailed measurements of the magnetic relaxation expressed in the linewidth of the ferromagnetic resonance (FMR) absorption in thick films of yttrium iron garnet (YIG) and in YIG/Pt bilayers carried out at room temperature reveal a very large increase in the relaxation rate with the deposition of a Pt layer. The additional relaxation increases linearly with the microwave frequency characteristics of the spin pumping mechanism. The value of the spin mixing conductance obtained from the data is one order of magnitude larger than the largest possible value determined from measurements of the voltage generated by FMR spin-pumping.

Rezende, S. M.; Rodríguez-Suárez, R. L.; Soares, M. M.; Vilela-Leão, L. H.; Ley Domínguez, D.; Azevedo, A.

2013-01-01

333

Electric field tuning of domain magnetic resonances in yttrium iron garnet films  

NASA Astrophysics Data System (ADS)

The converse magnetoelectric effect is studied by voltage tuning of magnetic resonance in a bilayer of (111) yttrium iron garnet (YIG) film and polycrystalline lead zirconate titanate (PZT) when the YIG film is in a multi-domain state or under magnetic saturation. The application of a DC voltage across PZT manifests as a uniaxial anisotropy field in YIG and results in a shift in the resonance. In the multi-domain state, the voltage tuning of resonance is strong with a magneto-electric coefficient A = 12 MHz cm/kV. Under magnetic saturation, the voltage tuning is rather weak with A = 2 MHz cm/kV.

Zavislyak, I. V.; Popov, M. A.; Sreenivasulu, G.; Srinivasan, G.

2013-06-01

334

Induced magneto-transport properties at palladium/yttrium iron garnet interface  

NASA Astrophysics Data System (ADS)

As a thin layer of palladium (Pd) is directly deposited on an yttrium iron garnet or YIG (Y3Fe5O12) magnetic insulator film, Pd develops both low- and high-field magneto-transport effects that are absent in standalone Pd or thick Pd on YIG. While the low-field magnetoresistance peak of Pd tracks the coercive field of the YIG film, the much larger high-field magnetoresistance and the Hall effect do not show any obvious relationship with the bulk YIG magnetization. The distinct high-field magneto-transport effects in Pd are shown to be caused by interfacial local moments in Pd.

Lin, Tao; Tang, Chi; Shi, Jing

2013-09-01

335

Epitaxial liftoff of thin oxide layers: Yttrium iron garnets onto GaAs  

NASA Astrophysics Data System (ADS)

We report on the implementation of epitaxial liftoff in magnetic garnets. Deep-ion implantation is used to create a buried sacrificial layer in single-crystal yttrium iron garnet (YIG) and bismuth-substituted YIG epilayers grown on gadolinium gallium garnet. The damage generated by the implantation induces a large etch selectivity between the sacrificial layer and the rest of the garnet. 10-?m-thick films of excellent quality are lifted off and bonded to silicon and GaAs substrates. No noticeable degradation in magnetic coercivity due to domain pinning is observed. Stress-induced microfracturing in the thin oxide layers is also addressed.

Levy, M.; Osgood, R. M., Jr.; Kumar, A.; Bakhru, H.

1997-11-01

336

Infrared-to-visible upconversion luminescence of Er 3+ doped barium–natrium–yttrium–fluoride phosphor  

Microsoft Academic Search

Infrared-to-visible upconversion luminescence has been investigated in Er3+-doped barium–natrium–yttrium–fluoride phosphor (BaxNayYzF2x+y+3z+3m:Erm) with different cation concentrations. Intense upconversion emissions around 530, 550, and 660nm corresponding to the 2H11\\/2, 4S3\\/2, and 4F9\\/2 transitions, respectively to the 4I15\\/2 ground state were observed when excited by CW laser radiation at 1550nm. We adopted the low-temperature combustion synthesis (LCS) method to decrease the phosphor particle

Liping Lu; Xiyan Zhang; Zhaohui Bai; Xiaochun Wang

2011-01-01

337

Fluorine contamination in yttrium-doped barium zirconate film deposited by atomic layer deposition  

SciTech Connect

The authors have investigated the change of chemical composition, crystallinity, and ionic conductivity in fluorine contaminated yttrium-doped barium zirconate (BYZ) fabricated by atomic layer deposition (ALD). It has been identified that fluorine contamination can significantly affect the conductivity of the ALD BYZ. The authors have also successfully established the relationship between process temperature and contamination and the source of fluorine contamination, which was the perfluoroelastomer O-ring used for vacuum sealing. The total removal of fluorine contamination was achieved by using all-metal sealed chamber instead of O-ring seals.

An Jihwan; Beom Kim, Young; Sun Park, Joong; Hyung Shim, Joon; Guer, Turgut M.; Prinz, Fritz B. [Stanford University, Department of Mechanical Engineering, 440 Escondido Mall, Bldg. 530, Rm. 226, Stanford, California 94305 (United States); Stanford University, Department of Mechanical Engineering, 440 Escondido Mall, Bldg. 530, Rm. 226, Stanford, California 94305 (United States) and Korea University, Department of Mechanical Engineering, Seoul 136-701 (Korea, Republic of); Stanford University, Department of Materials Science and Engineering, 440 Escondido Mall, Bldg. 530, Rm. 226, Stanford, California 94305 (United States); Stanford University, Department of Mechanical Engineering and Department of Materials Science and Engineering, 440 Escondido Mall, Bldg. 530, Rm. 226, Stanford, California 94305 (United States)

2012-01-15

338

HRTEM Study of yttrium oxide particles in ODS steels for fusion reactor application  

Microsoft Academic Search

An oxide dispersion strengthened ferritic-martensitic steel with yttrium oxide (Y2O3) was produced by mechanical alloying and hot isostatic pressing techniques for high-performance structures of fusion energy devices. The structure of the nanometer-sized Y2O3 particles analysed by HRTEM shows a strong correlation of its crystallographic orientation with the alloy lattice. The orientation correlations [110]YO?[111]FeCr and (11?1?)YO?(11?0)FeCr were found. The strong orientation

M. Klimiankou; R. Lindau; A. Möslang

2003-01-01

339

Integration of nonlinear dielectric barium strontium titanate with polycrystalline yttrium iron garnet  

NASA Astrophysics Data System (ADS)

Biaxially oriented nonlinear dielectric Ba0.6Sr0.4TiO3 (BST) films have been grown on polycrystalline ferrite yttrium iron garnet (YIG) substrates. We use a structurally and chemically compatible MgO buffer to improve the crystallinity of the BST on polycrystalline YIG substrates, where the biaxially oriented MgO is deposited by an ion-beam assisted-deposition technique. The biaxially oriented BST has a dielectric loss of less than 0.01 and a capacitance tunability of greater than 25% at a direct current bias voltage of 40 V at room temperature.

Jia, Q. X.; Groves, J. R.; Arendt, P.; Fan, Y.; Findikoglu, A. T.; Foltyn, S. R.; Jiang, H.; Miranda, F. A.

1999-03-01

340

Adhesion after erbium, chromium:yttrium-scandium-gallium-garnet laser application at three different irradiation conditions  

Microsoft Academic Search

The aim of this study was to investigate whether distinct cooling of low fluence erbium, chromium:yttrium-scandium-gallium-garnet\\u000a (Er,Cr:YSGG) laser irradiation would influence adhesion. Main factors tested were: substrates (two), irradiation conditions\\u000a (three), and adhesives (three). A 750 ?m diameter tip was used, for 50 s, 1 mm from the surface, with a 0.25 W power output,\\u000a 20 Hz, energy density of 2.8 J\\/cm2 with energy per pulse

Sérgio Brossi Botta; Patricia Aparecida da Ana; Denise Maria Zezell; John M. Powers; Adriana Bona Matos

2009-01-01

341

Eu 3+ doped yttrium oxysulfide nanocrystals - crystallite size and luminescence transition(s)  

NASA Astrophysics Data System (ADS)

Nanocrystals of yttrium oxysulfide doped with trivalent europium has been synthesized using a two step sol-gel polymer thermolysis method employing urea formaldehyde resin in the presence of ethylene diamine tetra acetic acid as chelating agent. In this synthesis, marginal tunability in crystallite size ( ? = 7-15 nm) was achieved by varying the concentration of reactants and organic precursors. In this nanocrystalline system, various luminescence transitions, in particular 5D 0 ? 7F 2 transition of Eu 3+ shows moderate (˜ 60%) lifetime shortening which can be explained by considering possible increase in non-radiative rate ( ?nr) and also possible modification in optical electronegativity induced by surface states of the crystallites.

Dhanaraj, J.; Geethalakshmi, M.; Jagannathan, R.; Kutty, T. R. N.

2004-03-01

342

Cooling of Er(3+) with Tm(3+) for accurate temperature sensing using yttrium silicate compact powders.  

PubMed

Er(3+) doped nanocrystalline powders are extensively used for thermometry based on luminescence spectral analysis. The luminescence from Er(3+) is produced by a nonlinear (two-photon) absorption process which may generate strong internal heat by activation of nonradiative relaxation channels. If the heat dissipation is not efficient, as is the case for compact powders, there will be inaccurate readings of the temperature. Our proposed solution is to cool down Er(3+) by transferring part of its accumulated energy to another rare-earth element in the lattice. Here, we show our results for Er(3+)-Tm(3+) co-doped yttrium silicate powders prepared by combustion synthesis. PMID:25232991

Rakov, Nikifor; Maciel, Glauco S

2014-10-01

343

A process for the separation and purification of yttrium-90 for medical applications  

DOEpatents

An extraction chromatographic method for the preparation of {sup 90}Y of high chemical and radiochemical purity is disclosed. After an initial purification of a {sup 90}Sr stock solution and a suitable period of {sup 90}Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the {sup 90}Sr content of the mixture by a factor of about 10{sup 3}. The {sup 90}Y remaining is freed from any residual {sup 90}Sr, from its {sup 90}Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.

Horwitz, P.E.; Dietz, M.L.

1993-01-01

344

Histological Changes in Nontumoral Liver Secondary to Radioembolization of Hepatocellular Carcinoma with Yttrium 90-impregnated Microspheres: Report of Two Cases.  

PubMed

Transarterial radioembolization (TARE) with yttrium-90 is a minimally invasive locoregional therapy for hepatocellular carcinoma (HCC), and involves selective delivery of glass or resin microspheres impregnated with radioactive yttrium-90 into small arteries preferentially supplying the tumor for tumoricidal effect thus sparing the nontumoral liver, or into lobar artery to induce atrophy and contralateral hypertrophy. Clinically, post-TARE a small proportion of cases develop radioembolization-induced liver disease. Histological changes of TARE on nontumoral liver parenchyma have not been well characterized. Herein, we report two cases of liver resections for HCC post-TARE, and describe the histological changes in nontumoral liver parenchyma. PMID:25369308

Dhingra, Sadhna; Schwartz, Myron; Kim, Edward; Mabel Ko, Huaibin; Ward, Stephen C; Fiel, M Isabel; Thung, Swan N

2014-11-01

345

Sputter target  

DOEpatents

The disclosure relates to an improved sputter target for use in the deposition of hard coatings. An exemplary target is given wherein titanium diboride is brazed to a tantalum backing plate using a gold-palladium-nickel braze alloy.

Gates, Willard G. (Kansas City, MO); Hale, Gerald J. (Overland Park, KS)

1980-01-01

346

Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88  

PubMed Central

Staphylococcal enterotoxin B (SEB) exposure triggers an exaggerated pro-inflammatory cytokine response that often leads to toxic shock syndrome (TSS) associated with organ failure and death. MyD88 mediates pro-inflammatory cytokine signaling induced by SEB exposure and MyD88?/? mice are resistant to SEB intoxication, suggesting that MyD88 may be a potential target for therapeutic intervention. We targeted the BB loop region of the Toll/IL-1 receptor (TIR) domain of MyD88 to develop small-molecule therapeutics. Here, we report that a synthetic compound (EM-163), mimic to dimeric form of BB-loop of MyD88 attenuated tumor necrosis factor (TNF)- ?, interferon (IFN)-?, interleukin (IL)-1?, IL-2 and IL-6 production in human primary cells, whether administered pre- or post-SEB exposure. Results from a direct binding assay, and from MyD88 co-transfection/co-immunoprecipitation experiments, suggest that EM-163 inhibits TIR-TIR domain interaction. Additional results indicate that EM-163 prevents MyD88 from mediating downstream signaling. In an NF-kB-driven reporter assay of lipopolysaccharide-stimulated MyD88 signaling, EM-163 demonstrated a dose-dependent inhibition of reporter activity as well as TNF-? and IL-1? production. Importantly, administration of EM-163 pre- or post exposure to a lethal dose of SEB abrogated pro-inflammatory cytokine responses and protected mice from toxic shock-induced death. Taken together, our results suggest that EM-163 exhibits a potential for therapeutic use against SEB intoxication. PMID:22848400

Kissner, Teri L.; Ruthel, Gordon; Alam, Shahabuddin; Mann, Enrique; Ajami, Dariush; Rebek, Mitra; Larkin, Eileen; Fernandez, Stefan; Ulrich, Robert G.; Ping, Sun; Waugh, David S.; Rebek, Julius; Saikh, Kamal U.

2012-01-01

347

Application of SAC88 to Estimating Hydrologic Effects of Fire on a  

E-print Network

Application of SAC88 to Estimating Hydrologic Effects of Fire on a Watersheds1 R. Larry Ferral2 Abstract: SAC88 is a major revision of the Sacramento Model, which was developed in 1969 with minor exceeds the rate at which water can enter the upper level storages. SAC88 REVISIONS SAC88, a major

Standiford, Richard B.

348

STS-88 Mission Specialist James Newman suits up before launch  

NASA Technical Reports Server (NTRS)

In the Operations and Checkout Building, STS-88 Mission Specialist James H. Newman takes part in a complete suit check before launch. Newman holds a toy dog, 'Pluto,' representing the crew nickname Dog Crew 3 and Newman's nickname, Pluto. Mission STS-88 is expected to launch at 3:56 a.m. EST with the six-member crew aboard Space Shuttle Endeavour on Dec. 3. Endeavour carries the Unity connecting module, which the crew will be mating with the Russian-built Zarya control module already in orbit. In addition to Unity, two small replacement electronics boxes are on board for possible repairs to Zarya batteries. The mission is expected to last 11 days, 19 hours and 49 minutes, landing at 10:17 p.m. EST on Dec. 14.

1998-01-01

349

Surface Observed Global Land Precipitation Variations during 1900–88  

Microsoft Academic Search

The authors have analyzed global station data and created a gridded dataset of monthly precipitation for the period of 1900-88. Statistical analyses suggest that discontinuities associated with instrumental errors are large for many high-latitude station records, although they are unlikely to be significant for the majority of the stations. The first leading EOF in global precipitation fields is an ENSO-related

Aiguo Dai; Inez Y. Fung; Anthony D. Del Genio

1997-01-01

350

PET computer programs for use with the 88-inch cyclotron  

SciTech Connect

This report describes in detail several offline programs written for the PET computer which provide an efficient data management system to assist with the operation of the 88-Inch Cyclotron. This function includes the capability to predict settings for all cyclotron and beam line parameters for all beams within the present operating domain of the facility. The establishment of a data base for operational records is also described from which various aspects of the operating history can be projected.

Gough, R.A.; Chlosta, L.

1981-06-01

351

An 88-kilodalton antigen secreted by Aspergillus fumigatus.  

PubMed Central

An 88-kDa component secreted in vitro by Aspergillus fumigatus has been purified by sequential chromatographic procedures. The molecule is a glycoprotein with an N-linked sugar moiety composed of mannose glucose, and galactose (16:10:1). It is recognized by antibodies from patients with aspergilloma and has potential for the immunodiagnosis of aspergilloma. The antigenicity is associated with the polypeptide part of the molecule (79 kDa). Images PMID:8406876

Kobayashi, H; Debeaupuis, J P; Bouchara, J P; Latge, J P

1993-01-01

352

88. Groundhog Mountain. View of the log fire lookout constructed ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. Groundhog Mountain. View of the log fire lookout constructed by the Virginia State Forest service in the summer of 1942. A buck or Yankee fence crosses the foreground with a snake fence in the background. Civilian public service employees began erecting the rail fences in April 1939. Looking north-northeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

353

[Fetal pathology study of 88 cases of letal spina bifida].  

PubMed

Lethal spina bifida continue to be frequent in Tunisia; we report 88 cases of letal spina bifida: 1.05 per thousand births. This pathology was more frequent with women. The up letal spina bifida situated is predominant with female and the dow spina bifida situated is frequent with male. We have noted an association with anencephalia (46 cases) and hydrocephaly (21 cases). Prevention is based on obstetric health care and hygiene dietetic advices to avoid alimentary deficit. PMID:11155378

Gaigi, S S; Masmoudi, A; Mahjoub, S; Jabnoun, S; Ouni, S; Channoufi, M B; Oueslati, H; Chabchoub, A; Marrakchi, Z; Sfar, E; Lebbi, I; Rezigua, H; Zouari, F; Chelli, H; Khrouf, N

2000-12-01

354

Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence  

PubMed Central

Toll-like receptor signaling requires functional Toll/interleukin-1 (IL-1) receptor (TIR) domains to activate innate immunity. By producing TIR homologous proteins, microbes inhibit host response induction and improve their own survival. The TIR homologous protein TcpC was recently identified as a virulence factor in uropathogenic Escherichia coli (E. coli), suppressing innate immunity by binding to MyD88. This study examined how the host MyD88 genotype modifies the in vivo effects of TcpC and whether additional, TIR-domain containing proteins might be targeted by TcpC. In wild type mice (wt), TcpC enhanced bacterial virulence, increased acute mortality, bacterial persistence and tissue damage after infection with E. coli CFT073 (TcpC+), compared to a ?TcpC deletion mutant. These effects were attenuated in Myd88?/? and Tlr4?/? mice. Transcriptomic analysis confirmed that TcpC inhibits MYD88 dependent gene expression in CFT073 infected human uroepithelial cells but in addition the inhibitory effect included targets in the TRIF and IL-6/IL-1 signaling pathways, where MYD88 dependent and independent signaling may converge. The effects of TcpC on bacterial persistence were attenuated in Trif ?/? or Il-1? ?/? mice and innate immune responses to ?TcpC were increased, confirming that Trif and Il-1? dependent targets might be involved in vivo, in addition to Myd88. Furthermore, soluble TcpC inhibited Myd88 and Trif dependent TLR signaling in murine macrophages. Our results suggest that TcpC may promote UTI-associated pathology broadly, through inhibition of TIR domain signaling and downstream pathways. Dysregulation of the host response by microbial TcpC thus appears to impair the protective effects of innate immunity, while promoting inflammation and tissue damage. PMID:20886104

Yadav, Manisha; Zhang, Jingyao; Fischer, Hans; Huang, Wen; Lutay, Nataliya; Cirl, Christine; Lum, Josephine; Miethke, Thomas; Svanborg, Catharina

2010-01-01

355

Population Files for use with CAP88 at Los Alamos  

SciTech Connect

CAP88 (Clean Air Act Assessment Package 1988) is a computer model developed for the US Environmental Protection Agency to assess the potential dose from radionuclide emissions to air and to demonstrate compliance with the Clean Air Act. It has options to calculate either individual doses, in units of mrem, or a collective dose, also called population dose, in units of person-rem. To calculate the collective dose, CAP88 uses a population file such as LANL.pop, that lists the number of people in each sector (N, NNE, NE, etc.) as a function of distance (1 to 2 km, etc.) out to a maximum radius of 80 km. Early population files are described in the Los Alamos National Laboratory (LANL) Environmental Reports for 1985 (page 14) and subsequent years. LA-13469-MS describes a population file based on the 1990 census. These files have been updated several times, most recently in 2006 for CAP88 version 3. The 2006 version used the US census for 2000. The present paper describes the 2012 updates, using the 2010 census.

McNaughton, Michael W [Los Alamos National Laboratory; Brock, Burgandy R [Los Alamos National Laboratory

2012-07-10

356

Overexpression of FOXO3, MYD88, and GAPDH Identified by Suppression Subtractive Hybridization in Esophageal Cancer Is Associated with Autophagy  

PubMed Central

To find genes involved in tumorigenesis and the development of esophageal cancer, the suppression subtractive hybridization (SSH) method was used to identify genes that are overexpressed in esophageal cancer tissues compared to normal esophageal tissues. In our SSH library, the forkhead box O3 (FOXO3), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and myeloid differentiation primary response 88 (MYD88) genes were the most highly upregulated genes, and they were selected for further studies because of their potential role in the induction of autophagy. Upregulation of these genes was also observed in clinical samples using qRT-PCR. In addition, coexpression analysis of the autophagy-related genes Beclin1, ATG12, Gabarapl, PIK3C3, and LC3 demonstrated a significant correlation between the differentially overexpressed genes and autophagy. Autophagy is an important mechanism in tumorigenesis and the development of chemoresistance in cancer cells. The upregulation of FOXO3, GAPDH, and MYD88 variants in esophageal cancer suggests a role for autophagy and provides new insight into the biology of esophageal cancer. We propose that FOXO3, GAPDH, and MYD88 are novel targets for combating autophagy in esophageal cancer. PMID:24527027

Mottaghi-Dastjerdi, Negar; Setayesh, Neda; Roshandel, Gholamreza; Ebrahimifard, Farzaneh; Sepehrizadeh, Zargham

2014-01-01

357

Mycobacterium indicus pranii mediates macrophage activation through TLR2 and NOD2 in a MyD88 dependent manner.  

PubMed

Mycobacterium indicus pranii (MIP) is a non-pathogenic strain of mycobacterium and has been used as a vaccine against tuberculosis and leprosy. Here, we investigated the role of different pattern recognition receptors in the recognition of heat-killed MIP by macrophages. Treatment of macrophages with MIP caused upregulation of pro-inflammatory cytokines (like TNF? and IL-1?) which was mediated through both TLR2 and NOD2, as revealed by our knockdown and/or knockout studies. Mechanistically, MIP-induced macrophage activation was shown to result in NF-?B activation and drastically abrogated by MyD88 deficiency, suggesting its regulation via an MyD88-dependent, NF-?B pathway. Interestingly, the IFN-inducible cytokine, CXCL10, which is known target of the TRIF-dependent TLR pathway was found to be upregulated in response to MIP but, in an MyD88-dependent manner. Collectively, these results demonstrate macrophages to recognize and respond to MIP through a TLR2, NOD2 and an MyD88-dependent pathway. However, further studies should clarify whether additional TLR-dependent or -independent pathways also exist in regulating the full spectrum of MIP action on macrophage activation. PMID:22796586

Pandey, Rajeev Kumar; Sodhi, Ajit; Biswas, Subhra K; Dahiya, Yogesh; Dhillon, Manprit K

2012-08-24

358

ISAC targets  

NASA Astrophysics Data System (ADS)

The TRIUMF-ISAC radioactive ion beam facility was designed and constructed to allow irradiation of thick targets with up to 100 A proton beam intensities. Since beginning operation in 1998, beam intensities on ISAC targets have progressively increased toward the 100 A design limit. Routine operation with p + intensities up to 75 A is currently possible for both refractory metal target materials and for composite metal carbide materials; full 99 A p + intensity has been achieved for Nb foil target material. Consideration must be given to the beam power deposition, the power dissipation and the limiting temperature criteria of each target material. Increased beam power dissipation has been achieved by modifying target materials and target containers. Increasing irradiation currents have produced benefits, drawbacks and unexpected results for ISOL operations.

Dombsky, M.; Kunz, P.

2014-01-01

359

Electrical and Magnetic Properties of Nanostructured Mo-Doped Yttrium Iron Garnet  

NASA Astrophysics Data System (ADS)

Yttrium Iron Garnet (YIG) is a synthetic garnet and ferromagnetic with the chemical formula Y3Fe5O12. In YIG, five iron (III) ions occupy two octahedral and three tetrahedral sites, with yttrium (III) ions coordinated by eight oxygen ions in an irregular cube. The iron ions in the two coordination sites exhibit different spins, resulting in magnetic behavior. It is also transparent to infrared wavelengths over 600 nm. Nanostructured YIG has been synthesized systematically by solid state reaction method. The formation of pure YIG have been investigated through X-ray diffraction (XRD) beginning from weighing in molar proportions of Y2O3 and Fe2O3, mixing and grinding, pre-sintering and final sintering at 1300 ^oC. XRD study shows that YIG exhibits cubic structure with lattice constant of about 12 å. Magnetization with varying field and temperature has been measured using a SQUID magnetometer. Room temperature dielectric measurements indicate that the YIG shows the usual dielectric dispersion. Magnetic studies of Mo YIG has shown that it becomes diluted after doping and dielectric measurement have shown that dielectric constant of that sample has been reduced.

Khanra, S.; Laudari, A.; Kolekar, Y.; Kahol, P.; Ghosh, K.

2012-02-01

360

Short-term effects of intratracheal installations of yttrium barium copper oxide  

SciTech Connect

Inhalation exposures to the new high-temperature ({Tc}) superconductor (SC) materials can occur during manufacturing and fabrication processes. In this exploratory study, we examined the pulmonary response to the deposition of an yttrium barium copper oxide SC powder. Groups of Sprague-Dawley rats were intratracheally instilled with either 10 mg or 20 mg of SC in phosphate-buffered saline (PBS) or with PBS only. The animals were sacrificed 60 days later for histopathologic assessments of their lungs. Lung lesions in the 10-mg SC group were found mainly in alveolar ducts and proximal alveoli. The lesions consisted of variably sized foci of interstitial thickening involving accumulations of macrophages. These interstitial aggregates were often times centered around one or more extracellular crystals, which, presumably, were retained SC product. Trichome stains also demonstrated the presence of fibrosis in the walls of alveoli surrounding the granulomas. Similar interstitial-macrophage accumulations and fibrosis were observed in rats instilled with 20 mg of SC. However, alveolus like structures lined by ciliated cuboidal epithelium near interstitial granulomas were additionally found in the lungs of some of the animals in this latter group. These results suggest SC material of the yttrium barium copper oxide type may represent a potential exposure hazard to the lung.

London, J.E.; Newkirk, L.R.; Lehnert, B.E.

1990-12-01

361

Structure and conductivity of praseodymium and yttrium co-doped barium cerates  

NASA Astrophysics Data System (ADS)

Praseodymium-doped yttrium barium cerates were synthesised by solid-state reactions followed by quick sintering at 1500 °C for only 1 h achieving relative density > 96%. All studied compounds are stable in ambient air and reducing atmosphere (both wet and dry 5% H2-Ar). The Zr-free sample (BaCe0.7Y0.2Pr0.1O3-?) exhibits the highest conductivity of 0.0121 S cm-1 at 700 °C in air, comparable to results obtained for yttrium-doped barium cerate under similar conditions (0.014 S cm-1). Pr-doped compounds were also found to retain much larger amounts of water as suggested by the higher conductivities obtained in wet hydrogen comparing to the values in ambient air. This latter phenomenon is of special interest as it suggests the possibility of higher ionic conductivities in water-containing atmosphere. On the other hand, co-doping of praseodymium and bismuth did not yield the expected enhanced electrical properties from the bismuth addition probably due to structural factors influenced by the diminution of the cerium content.

Petit, Christophe T. G.; Tao, Shanwen

2013-03-01

362

Yttrium-succinates coordination polymers: Hydrothermal synthesis, crystal structure and thermal decomposition  

SciTech Connect

New polymeric yttrium-succinates, Y{sub 2}(C{sub 4}H{sub 4}O{sub 4}){sub 3}(H{sub 2}O){sub 4}.6H{sub 2}O and Y{sub 2}(C{sub 4}H{sub 4}O{sub 4}){sub 3}(H{sub 2}O){sub 2}, have been synthesized, and their structures (solved by single crystal XRD) are compared with that of Y{sub 2}(C{sub 4}H{sub 4}O{sub 4}){sub 3}(H{sub 2}O){sub 2}.H{sub 2}O. Three compounds were obtained as single phases, and their thermal behaviour is described. - Graphical abstract: In the field of coordination polymers or MOF's, few studies report on the polymorphs of Ln(III)-succinic acid. Here, we describe the hydrothermal synthesis and structural characterization of two novel yttrium-succinates coordination polymers, respectively 2D and 3D, Y{sub 2}(C{sub 4}H{sub 4}O{sub 4}){sub 3}(H{sub 2}O){sub 4}.6H{sub 2}O and Y{sub 2}(C{sub 4}H{sub 4}O{sub 4}){sub 3}(H{sub 2}O){sub 2}.

Amghouz, Zakariae; Roces, Laura; Garcia-Granda, Santiago [Departamentos de Quimica Fisica y Analitica y Quimica Organica e Inorganica, Universidad de Oviedo, 33006 Oviedo (Spain); Garcia, Jose R., E-mail: jrgm@uniovi.e [Departamentos de Quimica Fisica y Analitica y Quimica Organica e Inorganica, Universidad de Oviedo, 33006 Oviedo (Spain); Souhail, Badredine [Departement de Chimie, Faculte des Sciences, Universite Abdelmalek Essaadi, 93002 Tetouan, Maroc (Morocco); Mafra, Luis; Shi, Fa-nian; Rocha, Joao [Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro (Portugal)

2009-12-15

363

Process for making a titanium diboride-chromium diboride-yttrium titanium oxide ceramic composition  

DOEpatents

A ceramic composition composition is described. The ceramic composition consists essentially of from about 84 to 96 w/o titanium diboride, from about 1 to 9 w/o chromium diboride, and from about 3 to aobut 15 w/o yttrium-titanium-oxide. A method of making the ceramic composition is also described. The method of making the ceramic composition comprises the following steps: Step 1--A consolidated body containing stoichiometric quantities of titanium diboride and chromium diboride is provided. Step 2--The consolidated body is enclosed in and in contact with a thermally insulated package of yttria granules having a thickness of at least 0.5 inches. Step 3--The consolidated body enclosed in the thermally insulated package of yttria granules is heated in a microwave oven with microwave energy to a temperature equal to or greater than 1,900 degrees centigrade to sinter and uniformly disperse yttria particles having a size range from about 1 to about 12 microns throughout the consolidated body forming a densified body consisting essentially of titanium diboride, chromium diboride, and yttrium-titanium-oxide. The resulting densified body has enhanced fracture toughness and hardness.

Holcombe, Cressie E. (Knoxville, TN); Dykes, Norman L. (Oak Ridge, TN)

1992-01-01

364

Process for making a titanium diboride-chromium diboride-yttrium titanium oxide ceramic composition  

DOEpatents

A ceramic composition is described. The ceramic composition consists essentially of from about 84 to 96 w/o titanium diboride, from about 1 to 9 w/o chromium diboride, and from about 3 to about 15 w/o yttrium-titanium-oxide. A method of making the ceramic composition is also described. The method of making the ceramic composition comprises the following steps: Step 1--A consolidated body containing stoichiometric quantities of titanium diboride and chromium diboride is provided. Step 2--The consolidated body is enclosed in and in contact with a thermally insulated package of yttria granules having a thickness of at least 0.5 inches. Step 3--The consolidated body enclosed in the thermally insulated package of yttria granules is heated in a microwave oven with microwave energy to a temperature equal to or greater than 1,900 degrees centigrade to sinter and uniformly disperse yttria particles having a size range from about 1 to about 12 microns throughout the consolidated body forming a densified body consisting essentially of titanium diboride, chromium diboride, and yttrium-titanium-oxide. The resulting densified body has enhanced fracture toughness and hardness. No Drawings

Holcombe, C.E.; Dykes, N.L.

1992-04-28

365

Thermal stability studies of plasma sprayed yttrium oxide coatings deposited on pure tantalum substrate  

NASA Astrophysics Data System (ADS)

Plasma sprayed Yttrium oxide is used for coating of crucibles and moulds that are used at high temperature to handle highly reactive molten metals like uranium, titanium, chromium, and beryllium. The alloy bond layer is severely attacked by the molten metal. This commonly used layer contributes to the impurity addition to the pure liquid metal. Yttrium oxide was deposited on tantalum substrates (25 mm × 10mm × 1mm thk and 40 mm × 8mm × 1mm thk) by atmospheric plasma spray technique with out any bond coat using optimized coating parameters. Resistance to thermal shock was evaluated by subjecting the coated specimens, to controlled heating and cooling cycles between 300K to 1600K in an induction furnace in argon atmosphere having <= 0.1ppm of oxygen. The experiments were designed to examine the sample tokens by both destructive and non-destructive techniques, after a predetermined number of thermal cycles. The results upto 24 thermal cycles of 25 mm × 10mm × 1mm thk coupons and upto 6 cycles of 40 mm × 8mm × 1mm thk coupons are discussed. The coatings produced with the optimized parameters were found to exhibit excellent thermal shock resistance.

Nagaraj, A.; Anupama, P.; Mukherjee, Jaya; Sreekumar, K. P.; Satpute, R. U.; Padmanabhan, P. V. A.; Gantayet, L. M.

2010-02-01

366

Toll-Like Receptors and Cancer: MYD88 Mutation and Inflammation  

PubMed Central

Pattern recognition receptors (PRRs) expressed on immune cells are crucial for the early detection of invading pathogens, in initiating early innate immune response and in orchestrating the adaptive immune response. PRRs are activated by specific pathogen-associated molecular patterns that are present in pathogenic microbes or nucleic acids of viruses or bacteria. However, inappropriate activation of these PRRs, such as the Toll-like receptors (TLRs), due to genetic lesions or chronic inflammation has been demonstrated to be a major cause of many hematological malignancies. Gain-of-function mutations in the TLR adaptor protein MYD88 found in 39% of the activated B cell type of diffuse large B cell lymphomas and almost 100% of Waldenström’s macroglobulinemia further highlight the involvement of TLRs in these malignancies. MYD88 mutations result in the chronic activation of TLR signaling pathways, thus the constitutive activation of the transcription factor NF?B to promote cell survival and proliferation. These recent insights into TLR pathway driven malignancies warrant the need for a better understanding of TLRs in cancers and the development of novel anti-cancer therapies targeting TLRs. This review focuses on TLR function and signaling in normal or inflammatory conditions, and how mutations can hijack the TLR signaling pathways to give rise to cancer. Finally, we discuss how potential therapeutic agents could be used to restore normal responses to TLRs and have long lasting anti-tumor effects. PMID:25132836

Wang, James Q.; Jeelall, Yogesh S.; Ferguson, Laura L.; Horikawa, Keisuke

2014-01-01

367

Brillouin light scattering analysis of three-magnon splitting processes in yttrium iron garnet films Christoph Mathieu,* Valeri T. Synogatch,  

E-print Network

surface wave MSSW pulse signals in a long and narrow yttrium iron garnet film strip through three magnon that the launch and propagation of a relatively wide high-power magnetostatic surface wave MSSW pulse in a thin. The frequencies and k values match those predicted from the dispersion relations and energy and momentum

Patton, Carl

368

Origin of anomalous rare-earth element and yttrium enrichments in subaerially exposed basalts: Evidence from French Polynesia  

Microsoft Academic Search

Basalts from French Polynesian islands occasionally display extremely high abundances and anomalous distributions of rare-earth elements (REE) and yttrium, whereas other incompatible element concentrations and O, Sr, Nd and Pb isotopic ratios do not differ from those of “normal” basalts from the same area. The REE- and Y-enriched basalts contribute up to 15% of the sample set, suggesting that this

J. Cotten; A. Le Dez; M. Bau; M. Caroff; R. C. Maury; P. Dulski; S. Fourcade; M. Bohn; R. Brousse

1995-01-01

369

Rare-earth elements and yttrium distributions in mangrove coastal water systems: The western Gulf of Thailand  

Microsoft Academic Search

The concentration of rare-earth elements and yttrium (REY) was investigated in dissolved phase, suspended particulate matter, and seafloor sediments of the western coastal area of the Gulf of Thailand. The samples show Eu and Gd positive anomalies in the shale-normalized REY patterns, especially in the suspended particulate matter. On the other hand, a very high REE content was detected in

P. Censi; S. E. Spoto; G. Nardone; F. Saiano; R. Punturo; S. I. Di Geronimo; S. Mazzola; A. Bonanno; B. Patti; M. Sprovieri; D. Ottonello

2005-01-01

370

Influence of Water on the Domain Structure of Epitaxy Films of Gadolinium Iron Garnet and Yttrium Iron Garnet  

Microsoft Academic Search

The effect of moisture on the magnetic domain patterns of single-crystal gadolinium iron garnet and yttrium iron garnet was observed. The change in magnetic domain structure and the disappearance of magnetic ``bubble'' domains is related to a reduction of surface stresses by water.

H. Lessoff; P. J. Coane; T. E. Everhart; H. Kanter; C. Wells

1971-01-01

371

Synergistic separation of yttrium ions in lanthanide series from rare earths mixture via hollow fiber supported liquid membrane  

Microsoft Academic Search

Separation of yttrium ions from the mixture of rare earths in lanthanide series has been examined by a microporous hydrophobic hollow fiber supported liquid membrane. Cyanex 272 and TBP in kerosene are used separately as an extractant. Nitric acid solution is used as a stripping solution. Increasing the concentration of Cyanex 272 increases the percentages of extraction and stripping of

Prakorn Ramakul; Tossaporn Supajaroon; Tatchanok Prapasawat; Ura Pancharoen; Anchaleeporn W. Lothongkum

2009-01-01

372

Scandium, Chromium(VI), Gallium, Yttrium, Rhodium, Palladium, Indium in Mice: Effects on Growth and Life Span  

Microsoft Academic Search

In order to evaluate possible innate toxic effe'cts of small doses of scandium, hexavalent chromium, gallium, yttrium, indium, rhodium and palladium in terms of growth and survival, 958 mice divided as to sex were raised in an environment limited in metallic contamination and given 5 ppm metal in drinking water from weaning until natural death. Body weight was measured at

HENRY A. SCHROEDER; MARIAN MITCHENER

373

In situ high-temperature X-ray diffraction characterization of yttrium-implanted extra low-carbon steel  

SciTech Connect

Yttrium-implanted and unimplanted extra low-carbon steel samples were analyzed at T = 700 C and under an oxygen partial pressure P{sub O2} = 0.041Pa for 24 h to show the yttrium implantation effect on extra low-carbon steel high-temperature corrosion resistance. Sample oxidation weight gains were studied by thermogravimetry, and structural analyses were performed using in situ high-temperature X-ray diffraction with the same experimental conditions. The aim of this paper is to show the initial nucleation stage of the main compounds induced by oxidation at high temperatures according to the initial sample treatment (yttrium-implanted or unimplanted). The results obtained by in situ high-temperature X-ray diffraction will be compared to those by thermogravimetry to show the existing correlation between weight gain curves and structural studies. Results allow one to understand the improved corrosion resistance of yttrium-implanted extra low-carbon steel at high temperatures.

Caudron, E.; Buscail, H.; Perrier, S.

1999-11-01

374

Applications of an 88Y/Be photoneutron calibration source to dark matter and neutrino experiments.  

PubMed

The low-energy monochromatic neutron emission from an (88)Y/Be source can be exploited to mimic the few keV(nr) nuclear recoils expected from low-mass weakly interacting massive particles and coherent scattering of neutrinos off nuclei. Using this source, a target materials (superheated and noble liquids). PMID:23745854

Collar, J I

2013-05-24

375

Mal, more than a bridge to MyD88.  

PubMed

The family of type 1 transmembrane proteins known as Toll-like receptors (TLRs) provide early immune system recognition and response to infection. In order to transmit their signal to the nucleus and initiate activation of pro-inflammatory and anti-microbial genes, TLRs must initiate a cytoplasmic signalling cascade, which is alternately controlled by 6 known signalling adaptors. These signaling adaptors are crucial for activating the correct immune response to any given TLR / pathogen interaction. This review will focus on one of those adaptors, MyD88 adaptor-like (Mal), also known as TIRAP. Mal is critical for signalling by the best studied of the TLRs, the Gram negative bacterial lipopolysaccharide (LPS) sensor, TLR4. Mal's role in TLR2 signalling in response to activation of the bacterial lipopeptide receptor, TLR2, is more contentious. Mal is a component of the so-called 'MyD88-dependent pathway' in TLR4 signalling. Recent advances in our understanding of the signalling pathways downstream of Mal highlight MyD88-indpendent roles, thus positioning Mal as multifunctional and integral for the molecular control of bacterial infections as well as inflammatory diseases. Here we describe the sequence of molecular events involved in the signalling pathways controlled by Mal, and the importance of Mal in driving host protection against a variety of bacteria, with specific attention to the evidence for Mal's role in TLR2 signalling, recent structural findings that have altered our understanding of Mal signalling, and evidence that single nucleotide polymorphisms (SNPs) of Mal are responsible for variations in population level resistance and susceptibility to bacterial infection. PMID:23983209

Bernard, Nicholas J; O'Neill, Luke A

2013-09-01

376

Modified 8×8 quantization table and Huffman encoding steganography  

NASA Astrophysics Data System (ADS)

A new secure steganography, which is based on Huffman encoding and modified quantized discrete cosine transform (DCT) coefficients, is provided in this paper. Firstly, the cover image is segmented into 8×8 blocks and modified DCT transformation is applied on each block. Huffman encoding is applied to code the secret image before embedding. DCT coefficients are quantized by modified quantization table. Inverse DCT(IDCT) is conducted on each block. All the blocks are combined together and the steg image is finally achieved. The experiment shows that the proposed method is better than DCT and Mahender Singh's in PSNR and Capacity.

Guo, Yongning; Sun, Shuliang

2014-10-01

377

STS-88 Mission Highlights Resources Tape. Tape C  

NASA Technical Reports Server (NTRS)

The STS-88 flight crew, Commander Robert D. Cabana, Pilot Frederick W. Sturckow, and Mission Specialists Nancy J. Currie, James H. Newman, Jerry L. Ross, and Sergei Krikalev present a video overview of their space flight. This is the last of three videos which show the highlights of the mission. This video covers the last four days (day 9 - 12) of the mission. Important images include the closing of the UNITY Connecting Module's hatch, the crew exercising, and the reentry of the spacecraft into Earth's atmosphere.

1999-01-01

378

Comparative study of yttrium and rare-earth element behaviours in fluorine-rich hydrothermal fluids  

NASA Astrophysics Data System (ADS)

The mineral ‘fluorite’ is utilized as a probe to investigate the behaviour of the pseudolanthanide yttrium with respect to the lanthanides (rare-earth elements, REE) in fluorine-rich hydrothermal solutions. Hydrothermal vein fluorites are characterized by the close association of Y and REE, but in contrast to igneous and clastic rocks they show variable and non-chondritic Y/Ho ratios of up to 200. This suggests that Y and Ho, although similar in charge and size, may be fractionated in fluorine-rich medium-temperature aqueous fluids. In such solutions Y acts as a pseudolanthanide heavier than Lu. Y/Ho ratios of hydrothermal siderites are slightly below those of chondrites, suggesting that in (bi)carbonate-rich siderite-precipitating solutions Y may act as a Sm-like light pseudolanthanide. This indicates that Y-Ho fractionation is not a source-related phenomenon but depends on fluid composition. Based on these results it is strongly recommended that discussions of normalized REE patterns in general should be extended to normalized Rare-Earth-and-Yttrium (REY) patterns (Y inserted between Dy and Ho), because the slightly variable behaviour of the pseudolanthanide yttrium with respect to the REE may provide additional geochemical information. Available thermodynamic data suggest a negative correlation between Y/Ho and La/Ho during migration of a fluorite-precipitating hydrothermal solution. Cogenetic fluorites, therefore, should display either similar Y/Ho and similar La/Ho ratios, or a negative correlation between these ratios. This criterion may help to choose samples suitable for Sm-Nd isotopic studies prior to isotope analysis. However, in cogenetic hydrothermal vein fluorites the range of Y/Ho ratios is often almost negligible compared to the range of La/Ho ratios. This may be explained by modification of REE distributions by post-precipitation processes involving (partial) loss of a separate LREE-enriched phase. The presence of variable amounts of such an accessory phase in most fluorite samples is revealed by experiments employing stepwise incomplete fluorite decomposition. Fluorites derived from and deposited near to igneous rocks apparently display chondritic Y/Ho ratios close to those of their igneous source-rocks. However, a positive YSN anomaly is likely to develop as the distance between sites of REY mobilization and deposition increases.

Bau, Michael; Dulski, Peter

1995-03-01

379

Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis  

PubMed Central

Context: Therapeutic wounding includes wounding the skin to induce pigmentation of the depigmented skin patches that was earlier used for repigmenting small patches of stable vitiligo. In this study, we have used the same principle to induce pigmentation in idiopathic guttate hypomelanosis (IGH) by spot peel with 88% phenol. Aims: To study the efficacy of phenol in causing repigmentation in IGH and its adverse effect profile. Settings and Design: Open prospective study. Materials and Methods: Twenty patients with 139 IGH macules were subjected to spot peel. Eighty-eight percent phenol was applied with an ear bud once a month for two sittings. Patients were assessed both subjectively and objectively after every session and at the end of 3 months of initiation of therapy. Results: Repigmentation was noted in 64% of IGH macules. More than 75% improvement was seen in 45% of the total IGH macules, while 41.5% showed 50-75% improvement at the end of three months. Persistent scabbing was the common adverse effect noted in 17.26% of lesions. Conclusion: Spot peel with 88% phenol is a safe, simple, cost-effective, outpatient procedure for IGH, which can be combined with other medical therapies. PMID:24616848

Ravikiran, Shilpashree P.; Sacchidanand, S.; Leelavathy, B.

2014-01-01

380

Heavy ion cocktail beams at the 88 inch Cyclotron  

SciTech Connect

Cyclotrons in combination with ECR ion sources provide the ability to accelerate ''cocktails'' of ions. A cocktail is a mixture of ions of near-identical mass-to-charge (m/q) ratio. The different ions cannot be separated by the injector mass-analyzing magnet and are tuned out of the ion source together. The cyclotron then is utilized as a mass analyzer by shifting the accelerating frequency. This concept was developed soon after the first ECR ion source became operational at the 88-Inch Cyclotron and has since become a powerful tool in the field of heavy ion radiation effects testing. Several different ''cocktails'' at various energies are available at the 88-Inch cyclotron for radiation effect testing, covering a broad range of linear energy transfer and penetration depth. Two standard heavy ion cocktails at 4.5 MeV/nucleon and 10 MeV/nucleon have been developed over the years containing ions from boron to bismuth. Recently, following requests for higher penetration depths, a 15MeV/nucleon heavy ion cocktail has been developed. Up to nine different metal and gaseous ion beams at low to very high charge states are tuned out of the ion source simultaneously and injected together into the cyclotron. It is therefore crucial to balance the ion source very carefully to provide sufficient intensities throughout the cocktail. The paper describes the set-up and tuning of the ion source for the various heavy ion cocktails.

Leitner, Daniela; McMahan, Margaret A.; Argento, David; Gimpel, Thomas; Guy, Aran; Morel, James; Siero, Christine; Thatcher, Ray; Lyneis, Claude M.

2002-09-03

381

Lawrence's Legacy : Seaborg's Cyclotron - The 88-Inch Cyclotron turns 40  

NASA Astrophysics Data System (ADS)

In 1958, Sputnik had recently been launched by the Russians, leading to worry in Congress and increased funding for science and technology. Ernest Lawrence was director of the "Rad Lab" at Berkeley. Another Nobel Prize winner, Glenn Seaborg, was Associate Laboratory Director and Director of the Nuclear Chemistry Division. In this atmosphere, Lawrence was phoned by commissioners of the Atomic Energy Commission and asked what they could do for Seaborg, "because he did such a fine job of setting up the chemistry for extracting plutonium from spent reactor fuel" [1]. In this informal way, the 90-Inch (eventually 88-Inch) Cyclotron became a line item in the federal budget at a cost of 3M (later increased to 5M). The 88-Inch Cyclotron achieved first internal beam on Dec. 12, 1961 and first external beam in May 1962. Forty years later it is still going strong. Pieced together from interviews with the retirees who built it, Rad Lab reports and archives from the Seaborg and Lawrence collections, the story of its design and construction - on-time and under-budget - provides a glimpse into the early days of big science. [1] remarks made by Elmer Kelly, "Physicist-in-charge' of the project on the occasion of the 40th anniversary celebration.

McMahan, Margaret; Clark, David

2003-04-01

382

Hydrogen gas sensor based on palladium and yttrium alloy ultrathin film.  

PubMed

Compared with the other hydrogen sensors, optical fiber hydrogen sensors based on thin films exhibits inherent safety, small volume, immunity to electromagnetic interference, and distributed remote sensing capability, but slower response characteristics. To improve response and recovery rate of the sensors, a novel reflection-type optical fiber hydrogen gas sensor with a 10 nm palladium and yttrium alloy thin film is fabricated. The alloy thin film shows a good hydrogen sensing property for hydrogen-containing atmosphere and a complete restorability for dry air at room temperature. The variation in response value of the sensor linearly increases with increased natural logarithm of hydrogen concentration (ln[H(2)]). The shortest response time and recovery response time to 4% hydrogen are 6 and 8 s, respectively. The hydrogen sensors based on Pd(0.91)Y(0.09) alloy ultrathin film have potential applications in hydrogen detection and measurement. PMID:23278019

Yi, Liu; You-Ping, Chen; Han, Song; Gang, Zhang

2012-12-01

383

Synthesis of dense yttrium-stabilised hafnia pellets for nuclear applications by spark plasma sintering  

NASA Astrophysics Data System (ADS)

Dense yttrium-stabilised hafnia pellets (91.35 wt.% HfO2 and 8.65 wt.% Y2O3) were prepared by spark plasma sintering consolidation of micro-beads synthesised by the “external gelation” sol-gel technique. This technique allows a preparation of HfO2-Y2O3 beads with homogenous yttria-hafnia solid solution. A sintering time of 5 min at 1600 °C was sufficient to produce high density pellets (over 90% of the theoretical density) with significant reproducibility. The pellets have been machined in a lathe to the correct dimensions for use as neutron absorbers in an experimental test irradiation in the High Flux Reactor (HFR) in Petten, Holland, in order to investigate the safety of americium based nuclear fuels.

Tyrpekl, Vaclav; Holzhäuser, Michael; Hein, Herwin; Vigier, Jean-Francois; Somers, Joseph; Svora, Petr

2014-11-01

384

Yttrium enrichment and improved magnetic properties in partially melted Y-Ba-Cu-O materials  

NASA Technical Reports Server (NTRS)

The yttrium-rich compositions in the Y-Ba-Cu-O system were mapped out in a systematic manner to quantify their magnetic properties and to correlate them with the microstructure and phase composition as determined by scanning electron microscopy and X-ray diffraction analysis. It is found that the microstructure of Y-Ba-Cu-O compositions is a sensitive function of both their composition and processing conditions. Measurements of magnetic susceptibility and maximum (low-field) and remanent magnetization for the system Y:Ba:Cu = x:2:3 show highest values for x = 2. The corresponding structures involve numerous small crystals of Y2BaCuO5 (211) embedded in highly ordered assemblages of continous YBa2Cu3O(7-y) (123) layers.

Alterescu, Sidney; Hojaji, Hamid; Barkatt, Aaron; Michael, Karen A.; Hu, Shouxiang

1990-01-01

385

Mathematical model of metal-hydride phase change applied to Yttrium  

NASA Astrophysics Data System (ADS)

We present a mathematical model for the kinetics of hydriding and dehydriding of metal powders. The single powder particle is considered. Its shape is approximated by one of the symmetric ones: sphere, long thin cylinder (wire), or flat thin plate. A few concurrent processes are considered. The model equations are derived from the mass conservation law. We consider the case of the "shrinking core" morphology, i.e. formation of the hydride skin on the surface of the particle with subsequent growth of this skin. We consider three successive stages of the phase change: skin development, skin growth, and final saturation or degassing. We apply the model to experimental data for Yttrium and show that the approximation of the experimental curves by the model ones is comparable for different cycles and different shapes for similar sets of the kinetic parameters. This also shows that shape of powder particles do not influence significantly on the kinetics of hydriding and dehydriding.

Chernov, I. A.; Manicheva, S. V.; Gabis, I. E.

2013-08-01

386

Inverse spin Hall effect in nanometer-thick yttrium iron garnet/Pt system  

NASA Astrophysics Data System (ADS)

High quality nanometer-thick (20 nm, 7 nm, and 4 nm) epitaxial Yttrium Iron Garnet (YIG) films have been grown on gadolinium gallium garnet substrates using pulsed laser deposition. The Gilbert damping coefficient for the 20 nm thick films is 2.3 × 10-4 which is the lowest value reported for sub-micrometric thick films. We demonstrate Inverse spin Hall effect (ISHE) detection of propagating spin waves using Pt. The amplitude and the lineshape of the ISHE voltage correlate well to the increase of the Gilbert damping when decreasing thickness of YIG. Spin Hall effect based loss-compensation experiments have been conducted but no change in the magnetization dynamics could be detected.

d'Allivy Kelly, O.; Anane, A.; Bernard, R.; Ben Youssef, J.; Hahn, C.; Molpeceres, A. H.; Carrétéro, C.; Jacquet, E.; Deranlot, C.; Bortolotti, P.; Lebourgeois, R.; Mage, J.-C.; de Loubens, G.; Klein, O.; Cros, V.; Fert, A.

2013-08-01

387

Specific heat and thermal conductivity of ferromagnetic magnons in Yttrium Iron Garnet  

NASA Astrophysics Data System (ADS)

The specific heat and thermal conductivity of an insulating ferrimagnet Y3Fe5O12 (Yttrium Iron Garnet, YIG) single crystal were measured down to 50 mK. The ferromagnetic magnon specific heat Cm shows a characteristic T1.5-dependence down to 0.77 K. Below 0.77 K, a downward deviation is observed, which is attributed to the magnetic dipole-dipole interaction with typical magnitude of 10^{-4}\\ \\text{eV} . The ferromagnetic magnon thermal conductivity \\kappa_m does not show the characteristic T2-dependence below 0.8 K. To fit the \\kappa_m data, both magnetic defect scattering effect and dipole-dipole interaction are taken into account. These results provide a complete picture of the thermodynamic and thermal transport properties of the low-lying ferromagnetic magnons.

Pan, B. Y.; Guan, T. Y.; Hong, X. C.; Zhou, S. Y.; Qiu, X.; Zhang, H.; Li, S. Y.

2013-08-01

388

Spin valve effect of the interfacial spin accumulation in yttrium iron garnet/platinum bilayers  

NASA Astrophysics Data System (ADS)

We report the spin valve effect in yttrium iron garnet/platinum (YIG/Pt) bilayers. The spin Hall effect (SHE) generates spin accumulation at the YIG/Pt interface and can be opened/closed by magnetization switching in the electrical insulator YIG. The interfacial spin accumulation was measured in both YIG/Pt and YIG/Cu/Pt structures using a planar Hall configuration. The spin valve effect remained, even after a 2 nm thick Cu layer was inserted between the YIG and Pt layers, which aimed to exclude the induced magnetization at the YIG/Pt interface. The transverse Hall voltage and switching field were dependent on the applied charge current density. The origin of this behavior can be explained by the SHE induced torque exerted on the domain wall, caused by the transfer of the spin angular momentum from the spin-polarized current to the YIG magnetic moment.

Jin, Lichuan; Zhang, Dainan; Zhang, Huaiwu; Tang, Xiaoli; Bai, Feiming; Zhong, Zhiyong; Fan, Xin; Xiao, John Q.

2014-09-01

389

A wideband electronically tunable microwave notch filter in yttrium iron garnet-gallium arsenide material structure  

NASA Astrophysics Data System (ADS)

A wideband electronically tunable microwave notch (band-stop) filter has been constructed in an yttrium iron garnet (YIG)/gallium arsenide (GaAs) material structure. An incident microwave propagating along the microstrip transmission line in the GaAs substrate is coupled into and to excite the magnetostatic surface waves in the YIG layer, which is laid upon the microstrip transmission line. Maximum coupling and thus the peak absorption of the output microwave power occur at the ferromagnetic resonance frequency in the YIG film as determined by a bias magnetic field. A tuning range as large as 2.5-23.0 GHz in the peak absorption frequency with the corresponding magnetic field tuning range of 290-7300 Oe has been accomplished. Peak absorption of 15-38 dB in the microwave output power has also been measured.

Tsai, Chen S.; Su, Jun

1999-04-01

390

Yttrium silicate oxidation protective coating for SiC coated carbon\\/carbon composites  

Microsoft Academic Search

Four kinds of yttrium silicate oxidation protective coatings SiO2·Y2O3, 1.5SiO2·Y2O3, 1.5SiO2·Y2O3\\/SiO2·Y2O3 and 2SiO2·Y2O3\\/1.5SiO2·Y2O3\\/SiO2·Y2O3 were prepared by plasma spray on the surface of SiC pre-coated carbon\\/carbon composites. The structures of the coatings were characterized by XRD, SEM and EDS analyses. It was shown that the gradied 2SiO2·Y2O3\\/1.5SiO2·Y2O3\\/SiO2·Y2O3 multi-layer coating had better high-temperature oxidation resistance. It could protect carbon\\/carbon composites from oxidation

Jian-Feng Huang; He-Jun Li; Xie-Rong Zeng; Ke-Zhi Li

2006-01-01

391

Yttrium-90 radioembolization of liver tumors: what do the images tell us?  

PubMed Central

Abstract Transarterial radioembolization (TARE) with yttrium 90 microspheres is an increasingly popular therapy for both primary and secondary liver malignancies. TARE entails delivery of ?-particle brachytherapy and embolization of the tumor vasculature. The consequent biological sequelae are distinct from those of other transarterial therapies for liver tumors, as reflected in the often baffling post-treatment imaging features. As the clinical use of TARE is increasing, more diverse post-treatment radiological findings are encountered with variable overlap among treatment response, residual disease, reactionary changes and complications. Thus, post-TARE image interpretation is challenging. This review provides a comprehensive description of the different findings seen in post-treatment scans, with the aim of facilitating appropriate radiological interpretation of post-TARE pathologic changes, notwithstanding their existing limitations. PMID:24434228

Singh, Pavel

2013-01-01

392

Luminescence and absorption of divalent ytterbium ion in yttrium-aluminum garnet ceramics  

NASA Astrophysics Data System (ADS)

Strong absorption bands at 280, 385, and 640 nm; a pulsed cathodoluminescence band with peaks at 325 and 520 nm and a dip at 385 nm; and a structured luminescence band in the range of 591-711 nm composed of four pair lines and having a dip near 640 nm have been observed in the spectra of yttrium-aluminum garnet ceramics activated with ytterbium (10 mol %) and subjected to vacuum sintering at a temperature of 1800°C. It is shown that these spectral features are absorption and luminescence bands of divalent ytterbium ions with the 4 f 136 s electron configuration of the ground state. These ions occupy the cubic site that is formed under conditions of oxygen deficit and disappears when the latter is removed during annealing ceramics in air.

Solomonov, V. I.; Osipov, V. V.; Spirina, A. V.

2014-09-01

393

High-temperature acoustic emission sensing tests using a yttrium calcium oxyborate sensor.  

PubMed

Piezoelectric materials have been broadly utilized in acoustic emission sensors, but are often hindered by the loss of piezoelectric properties at temperatures in the 500°C to 700°C range or higher. In this paper, a piezoelectric acoustic emission sensor was designed and fabricated using yttrium calcium oxyborate (YCOB) single crystals, followed by Hsu-Nielsen tests for high-temperature (>700°C) applications. The sensitivity of the YCOB sensor was found to have minimal degradation with increasing temperature up to 1000°C. During Hsu-Nielsen tests with a steel bar, this YCOB acoustic sensor showed the ability to detect zero-order symmetric and antisymmetric modes at 30 and 120 kHz, respectively, as well as distinguish a first-order antisymmetric mode at 240 kHz at elevated temperatures up to 1000°C. The frequency characteristics of the signal were verified using a finite-element model and wavelet transformation analysis. PMID:24800684

Johnson, Joseph A; Kim, Kyungrim; Zhang, Shujun; Wu, Di; Jiang, Xiaoning

2014-05-01

394

First-principles calculations of the high-temperature phase transformation in yttrium tantalate  

NASA Astrophysics Data System (ADS)

The high-temperature phase transition between the tetragonal (scheelite) and monoclinic (fergusonite) forms of yttrium tantalite (YTaO4 ) has been studied using a combination of first-principles calculations and a Landau free-energy expansion. Calculations of the Gibbs free energies show that the monoclinic phase is stable at room temperature and transforms to the tetragonal phase at 1430 °C, close to the experimental value of 1426±7 °C. Analysis of the phonon modes as a function of temperature indicate that the transformation is driven by softening of transverse acoustic modes with symmetry Eu in the Brillouin zone center rather than the Raman-active Bg mode. Landau free-energy expansions demonstrate that the transition is second order and, based on the fitting to experimental and calculated lattice parameters, it is found that the transition is a proper rather than a pseudoproper type. Together these findings are consistent with the transition being ferroelastic.

Feng, Jing; Shian, Samuel; Xiao, Bing; Clarke, David R.

2014-09-01

395

8-Quinolinolate complexes of yttrium and ytterbium: molecular arrangement and fragmentation under laser impact.  

PubMed

New 8-quinolinolate (Q) complexes of yttrium (1) and ytterbium (2) were synthesized by the reactions of Cp3Y and Yb[N(SiMe3)2]3 with 3 equiv. of 8-hydroxyquinoline in a DME solution. Single crystal X-ray analysis revealed the trinuclear molecular structure of the compounds Ln3Q9. The LDI-TOFMS investigation displayed that under the laser impact the compounds split off Q(-) anions to give Ln3Q8(+), Ln2Q5(+) and LnQ3(+) moieties. In the negative mode spectra the anions Q(-) and LnQ4(-) were observed. The DFT calculations showed the decreased stability of cationic Ln-quinolinolate as compared with their anionic counterparts. Complex 2 which is used as an emitter in a three-layer OLED displayed a metal-centered emission at 979 nm and an intensity of 50 ?W cm(-2) at 15.5 V. PMID:24048370

Baranov, Evgeny V; Fukin, Georgy K; Balashova, Tatyana V; Pushkarev, Anatoly P; Grishin, Ivan D; Bochkarev, Mikhail N

2013-11-28

396

Optical properties of amorphous, erbium-doped yttrium alumino-borate thin films  

NASA Astrophysics Data System (ADS)

In this paper, we report on the optical characterizations of erbium-doped yttrium alumino-borate glassy thin films prepared by the polymeric precursor and sol-gel routes and the spin-coating technique. High quality planar waveguides were produced by a multilayer processing of Y 1-xEr xAl 3(BO 3) 4 compositions with x = 0.02, 0.05, 0.10, 0.30, and 0.50. Their optical properties were investigated using transmission, photoluminescence, and m-lines spectroscopy, whereas high resolution scanning electron microscopy (HR-SEM) was applied to check film thickness and surface homogeneity. The refractive indices determined from transmission and m-lines spectroscopy are in good agreement just like the film thickness measured by HR-SEM and transmission spectroscopy. We observed low propagation losses, together with efficient photoluminescence emission for polymeric precursor thin films, involving low cost and environment friendly reactants.

Maia, L. J. Q.; Fick, J.; Hernandes, A. C.; Mastelaro, V. R.; Ibanez, A.

2012-02-01

397

http://www.sjsu.edu/senate/f88-6.htm F88-6 NON-TRADITIONAL GRADING; CREDIT/NO CREDIT  

E-print Network

http://www.sjsu.edu/senate/f88-6.htm F88-6 NON-TRADITIONAL GRADING; CREDIT/NO CREDIT (PASS ON NON-TRADITIONAL GRADING F 88-6 Supersedes S 73-12. Resolved, A, B, C, D, F, shall be the basic grading the first four weeks of instruction change the option from Credit/No Credit to a traditional grading system

Gleixner, Stacy

398

Cathodoluminescent properties of an Am3+ ion in a matrix of yttrium-aluminum garnet Y3Al5O12  

NASA Astrophysics Data System (ADS)

The luminescent properties of an americium ion are studied. Luminescence spectra of americium in yttrium-aluminum garnet are recorded for the first time. The luminescence bands are identified, and the levels responsible for the observed optical transitions are determined.

Kuznetsova, Ya. V.; Usacheva, V. P.; Zamoryanskaya, M. V.

2014-03-01

399

Spin Fluctuations in (cerium, YTTRIUM)COBALT-2 and Related Systems.  

NASA Astrophysics Data System (ADS)

The pseudobinary alloy systems (Y_ {rm x}Zr_{1 -rm x})Co_2, (Y _{rm x}Ce _{1-rm x})Co_2 , and (Ce_{rm x} Zr_{1-rm x})Co _2, for 0 < x < 1, have been studied. The temperature dependence of the electrical resistivity, magnetic susceptibility and specific heat have been measured for these systems. The temperature ranges were: for the electrical resistivity 1.5 to 300 K, for the magnetic susceptibility 6 to 300 K and for the specific heat 1.5 to 25 K. All three measurements show a rapid falloff of enhancements due to d-electron spin fluctuations as yttrium is replaced by zirconium in the (Y,Zr)Co_2 system. The variation of both the magnetic susceptibility and the specific heat as one substitutes cerium for yttrium in the (Y,Ce)Co _2 system is strikingly similar to that observed for (Y,Zr)Co_2. However, the resistivity of the (Y,Ce)Co_2 system is markedly different from that observed in (Y,Zr)Co_2 . Measurements done on the (Ce,Zr)Co_2 system confirm both the similarities between CeCo _2 and ZrCo_2 seen in the magnetic susceptibility and specific heat and the difference seen in the resistivity. Of greatest interest to this study is the evolution of the curvature of the temperature dependent magnetic susceptibility, which evolves from an upward bending form in YCo_2 to a downward bending form in both CeCo_2 and ZrCo_2 as predicted by theory for strongly enhanced paramagnets with a suitable density of states. This is the first controlled alloy study which shows such an evolution.

Timlin, John

400

Yttrium-90 Radioembolization in Patients with Hepatocellular Carcinoma Who have Previously Received Sorafenib  

PubMed Central

Purpose: Yttrium-90 radioembolization (RE) is a locoregional therapy option for hepatocellular carcinoma (HCC). Sorafenib is a multikinase inhibitor used in HCC that can potentially affect the efficacy of RE by altering tumor vascularity or suppressing post-irradiation angiogenesis. The safety and efficacy of sorafenib followed by RE has not been previously reported. Materials and Methods: Patients with HCC who received RE after sorafenib were included in this retrospective review. Overall survival, toxicity, and maximal radiographic response and necrosis criteria were examined. Results: Ten patients (15 RE administrations) fit the inclusion criteria. All were Barcelona Clinic Liver Cancer (BCLC) stage C. Median follow-up was 16.5?weeks. Median overall survival and radiographic progression-free survival were 30 and 28?weeks, respectively. Significant differences in overall survival were seen based on Child-Pugh class (p?=?0.002) and radiographic response (p?=?0.009). Three patients had partial response, six had stable disease, and one had progressive disease. Grade 1 or 2 acute fatigue, anorexia, and abdominal pain were common. Three patients had Grade 3 ascites in the setting of disease progression. Two patients had Grade 3 biochemical toxicity. One patient was sufficiently downstaged following RE and sorafenib to receive a partial hepatectomy. Conclusion: Yttrium-90 RE in patients with HCC who have received sorafenib demonstrate acceptable toxicity and rates of radiographic response. However, the overall survival is lower than that reported in the literature on RE alone or sorafenib alone. This may be due in part to more patients in this study having advanced disease compared to these other study populations. Larger prospective studies are needed to determine whether the combination of RE and sorafenib is superior to either therapy alone. PMID:24416722

Rana, Nitesh; Ju, Andrew Wenhua; Bazylewicz, Michael; Kallakury, Bhaskar; He, Aiwu Ruth; Unger, Keith R.; Lee, Justin S.

2013-01-01

401

Thermionic emission and surface composition of the lanthanum-boron and yttrium-boron systems  

SciTech Connect

At thermionic temperatures, a difference between bulk and surface composition will exist unless the interior happens to be at the congruently vaporizing composition (CVC). Vaporization rates from the surface compete with diffusion rates in the bulk to cause this difference. The surface composition will tend toward the congruently vaporizing composition which is YB/sub 4/ in the yttrium-Boron system and LaB/sub 6/ in the Lanthanum-Boron system. The CVC is also a function of temperature and may vary slightly for the same bulk composition at different temperature. Four Yttrium-Boron (Y-B) compounds, YB/sub 2/ /sub 5/, YB/sub 5/, YB/sub 6/ /sub 4/, YB/sub 14/ and three Lanthanum-Boron (La-B) compounds, LaB/sub 6/ /sub 01/, LaB/sub 8/ /sub 5/ and LaB/sub 5/ /sub 9/ were tested in a variable spacing vacuum emission system with a guard assembly. Emitted current measurements were made with interelctrode potentials between 250 and 1400 volts. Schottky plots were used to extrapolate the zero field currents. When a sample is taken from equilibrium to a new temperature, a definite time lag appears while vaporization rates change to bring about a new equilibrium surface composition. This manifests itself in the recorded emission currents. After thermal equilibrium is reached a distinct change is seen in emission currents. A higher density is measured, reflecting the emission of a surface that has been raised to a higher temperature. But with time, at this temperature, the surface reacts through vaporization and a new composition appears that is closer to the congruently vaporizing composition, and hence, has a work function nearer that of the CVC.

Jaskie, J.E.

1981-12-01

402

50 CFR 217.88 - Renewal of Letters of Authorization and adaptive management.  

Code of Federal Regulations, 2012 CFR

50 Wildlife and Fisheries 10 2012-10-01...88 Section 217.88 Wildlife and Fisheries NATIONAL...described work, mitigation or monitoring undertaken during the upcoming...reviewed, and accepted the monitoring reports required...

2012-10-01

403

50 CFR 217.88 - Renewal of Letters of Authorization and adaptive management.  

Code of Federal Regulations, 2013 CFR

50 Wildlife and Fisheries 10 2013-10-01...88 Section 217.88 Wildlife and Fisheries NATIONAL...described work, mitigation or monitoring undertaken during the upcoming...reviewed, and accepted the monitoring reports required...

2013-10-01

404

40 CFR 141.88 - Monitoring requirements for lead and copper in source water.  

Code of Federal Regulations, 2011 CFR

...requirements for lead and copper in source water. 141.88 Section 141.88 Protection...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper...

2011-07-01

405

40 CFR 141.88 - Monitoring requirements for lead and copper in source water.  

Code of Federal Regulations, 2013 CFR

...requirements for lead and copper in source water. 141.88 Section 141.88 Protection...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper...

2013-07-01

406

40 CFR 141.88 - Monitoring requirements for lead and copper in source water.  

Code of Federal Regulations, 2012 CFR

...requirements for lead and copper in source water. 141.88 Section 141.88 Protection...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper...

2012-07-01

407

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.  

Code of Federal Regulations, 2011 CFR

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2011-07-01

408

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.  

Code of Federal Regulations, 2012 CFR

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2012-07-01

409

40 CFR 88.204-94 - Sales requirements for the California Pilot Test Program.  

Code of Federal Regulations, 2010 CFR

...false Sales requirements for the California Pilot Test Program. 88.204-94...CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.204-94 Sales requirements for the California Pilot Test Program. (a)...

2010-07-01

410

40 CFR 88.206-94 - State opt-in for the California Pilot Test Program.  

Code of Federal Regulations, 2011 CFR

... false State opt-in for the California Pilot Test Program. 88.206-94...CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.206-94 State opt-in for the California Pilot Test Program....

2011-07-01

411

40 CFR 88.206-94 - State opt-in for the California Pilot Test Program.  

Code of Federal Regulations, 2010 CFR

... false State opt-in for the California Pilot Test Program. 88.206-94...CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.206-94 State opt-in for the California Pilot Test Program....

2010-07-01

412

40 CFR 88.206-94 - State opt-in for the California Pilot Test Program.  

Code of Federal Regulations, 2012 CFR

... false State opt-in for the California Pilot Test Program. 88.206-94...CONTINUED) CLEAN-FUEL VEHICLES California Pilot Test Program § 88.206-94 State opt-in for the California Pilot Test Program....

2012-07-01

413

40 CFR 81.88 - Billings Intrastate Air Quality Control Region.  

...2014-07-01 false Billings Intrastate Air Quality Control Region. 81.88 Section 81...CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.88 Billings...

2014-07-01

414

40 CFR 86.1312-88 - Weighing chamber and microgram balance specifications.  

Code of Federal Regulations, 2010 CFR

...false Weighing chamber and microgram balance specifications. 86.1312-88 Section...1312-88 Weighing chamber and microgram balance specifications. (a) Ambient conditions...the sample filters. (b) Weighing balance specifications. The microgram...

2010-07-01

415

42 CFR 88.13 - WTC Program Administrator's certification of health conditions.  

Code of Federal Regulations, 2011 CFR

42 Public Health 1 2011-10-01 2011-10-01 false WTC Program Administrator's...certification of health conditions. 88.13 Section 88.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

2011-10-01

416

42 CFR 88.13 - WTC Program Administrator's certification of health conditions.  

Code of Federal Regulations, 2012 CFR

42 Public Health 1 2012-10-01 2012-10-01 false WTC Program Administrator's...certification of health conditions. 88.13 Section 88.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

2012-10-01

417

42 CFR 88.13 - WTC Program Administrator's certification of health conditions.  

Code of Federal Regulations, 2013 CFR

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2013-10-01

418

10 CFR 1040.88 - Remedial and affirmative action by recipients.  

Code of Federal Regulations, 2011 CFR

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2011-01-01

419

10 CFR 1040.88 - Remedial and affirmative action by recipients.  

...2014-01-01 false Remedial and affirmative action by recipients. 1040.88... § 1040.88 Remedial and affirmative action by recipients. (a...discrimination, a recipient may take affirmative action to overcome the effects...

2014-01-01

420

10 CFR 1040.88 - Remedial and affirmative action by recipients.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 false Remedial and affirmative action by recipients. 1040.88... § 1040.88 Remedial and affirmative action by recipients. (a...discrimination, a recipient may take affirmative action to overcome the effects...

2013-01-01

421

10 CFR 1040.88 - Remedial and affirmative action by recipients.  

Code of Federal Regulations, 2010 CFR

...2010-01-01 false Remedial and affirmative action by recipients. 1040.88... § 1040.88 Remedial and affirmative action by recipients. (a...discrimination, a recipient may take affirmative action to overcome the effects...

2010-01-01

422

10 CFR 1040.88 - Remedial and affirmative action by recipients.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 false Remedial and affirmative action by recipients. 1040.88... § 1040.88 Remedial and affirmative action by recipients. (a...discrimination, a recipient may take affirmative action to overcome the effects...

2012-01-01

423

42 CFR 88.16 - Reimbursement for medically necessary treatment, outpatient prescription pharmaceuticals...  

Code of Federal Regulations, 2013 CFR

42 Public Health 1 2013-10-01 2013-10-01 false...prescription pharmaceuticals, monitoring, initial health evaluations, and travel expenses. 88.16 Section 88.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF...

2013-10-01

424

42 CFR 88.16 - Reimbursement for medically necessary treatment, outpatient prescription pharmaceuticals...  

Code of Federal Regulations, 2012 CFR

42 Public Health 1 2012-10-01 2012-10-01 false...prescription pharmaceuticals, monitoring, initial health evaluations, and travel expenses. 88.16 Section 88.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF...

2012-10-01

425

42 CFR 88.16 - Reimbursement for medically necessary treatment, outpatient prescription pharmaceuticals...  

Code of Federal Regulations, 2011 CFR

42 Public Health 1 2011-10-01 2011-10-01 false...prescription pharmaceuticals, monitoring, initial health evaluations, and travel expenses. 88.16 Section 88.16 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF...

2011-10-01

426

40 CFR 141.88 - Monitoring requirements for lead and copper in source water.  

...requirements for lead and copper in source water. 141.88 Section 141.88 Protection...ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper...

2014-07-01

427

33 CFR 88.09 - Temporary exemption from light and shape requirements when operating under bridges.  

Code of Federal Regulations, 2012 CFR

...shape requirements when operating under bridges. 88.09 Section 88.09 Navigation...shape requirements when operating under bridges. A vessel's navigation lights...lowered if necessary to pass under a...

2012-07-01

428

33 CFR 88.09 - Temporary exemption from light and shape requirements when operating under bridges.  

Code of Federal Regulations, 2010 CFR

...shape requirements when operating under bridges. 88.09 Section 88.09 Navigation...shape requirements when operating under bridges. A vessel's navigation lights...lowered if necessary to pass under a...

2010-07-01

429

33 CFR 88.09 - Temporary exemption from light and shape requirements when operating under bridges.  

Code of Federal Regulations, 2011 CFR

...shape requirements when operating under bridges. 88.09 Section 88.09 Navigation...shape requirements when operating under bridges. A vessel's navigation lights...lowered if necessary to pass under a...

2011-07-01

430

33 CFR 88.09 - Temporary exemption from light and shape requirements when operating under bridges.  

Code of Federal Regulations, 2013 CFR

...shape requirements when operating under bridges. 88.09 Section 88.09 Navigation...shape requirements when operating under bridges. A vessel's navigation lights...lowered if necessary to pass under a...

2013-07-01

431

Upcoming replacements for NAD83, NAVD88 and IGLD85  

NASA Astrophysics Data System (ADS)

The National Geodetic Survey (NGS), part of the National Oceanic and Atmospheric Administration (NOAA) is responsible for defining, maintaining and providing access to the National Spatial Reference System (NSRS) for the United States. The NSRS is the official system to which all civil federal mapping agencies should refer, and contains, amongst other things, the official geopotential (historically "vertical") datum of NAVD 88, the 3-D geometric reference system (historically "horizontal datum") of NAD 83 and great lakes datum (IGLD 85). Although part of the United States NSRS, all three of these datums have been created through international partnerships across North America. Unfortunately, time has shown both the systematic errors existent within these datums, as well as the inherent weaknesses of relying exclusively on passive monuments to define and provide access to these datums. In recognition of these issues, the National Geodetic Survey has issued a "10 year plan", available online, which outlines steps which will be taken to update NAD 83, NAVD 88 and IGLD 85 concurrently around the year 2018. The primary source of success will be in the refinement of the CORS network and the upcoming execution of the GRAV-D project (Gravity for the Re-definition of the American Vertical Datum). Conversations are ongoing with colleagues in Canada, Mexico, Central America and the Caribbean in order to coordinate all of these efforts across the entire continent. The largest changes expected to occur are the removal of over 2 meters of non-geocentricity in NAD 83; the removal of decimeters of bias and over a meter of tilt in NAVD 88; the addition of the ability to track crustal motions (subsidence, tectonics, etc) in the datums; the removal of leveling as a tool for long-line height differencing; the use of a "best" geoid as the orthometric height reference surface; the addition of datum velocities (motions of the 3-D geometric reference system origin and motions of the geoid); and the use of GNSS technology as the way to access both orthometric and dynamic heights in the vertical datum. This talk will outline the broad plan of action and invite further collaboration along these lines.

Smith, D. A.; Snay, R.

2009-05-01

432

UCDHS PeopleSoft HRMS 8.8 [Employee Self Service Applying for Jobs  

E-print Network

UCDHS PeopleSoft HRMS 8.8 [Employee Self Service ­ Applying for Jobs] 8.8 Employee SS - Applying for Jobs V4.0 9/12/2008 Employee User Guide Applying for Jobs #12;UCDHS PeopleSoft HRMS 8.8 ­ Employee Self Service ­ Applying for Jobs 8.8 Employee SS - Applying for Jobs V4.0 Page 2 of 15 1/31/2007 View Job

Nguyen, Danh

433

UCDHS PeopleSoft HRMS 8.8 [Employee Self Service Applying for Jobs  

E-print Network

UCDHS PeopleSoft HRMS 8.8 [Employee Self Service ­ Applying for Jobs] 8.8 Employee SS - Applying for Jobs V4.0 1/31/2007 Employee User Guide Applying for Jobs #12;UCDHS PeopleSoft HRMS 8.8 ­ Employee Self Service ­ Applying for Jobs 8.8 Employee SS - Applying for Jobs V4.0 Page 2 of 16 1/31/2007 View Job

Leistikow, Bruce N.

434

RESEARCH Open Access MyD88 is crucial for the development of a  

E-print Network

with AIDS, neoplastic diseases and organ transplants. Toll-like receptor (TLR) adaptor MyD88 activation but there was no histological change in the liver, heart, lungs and small intestine of MyD88-/- and MyD88+/+ mice. However, My

Paris-Sud XI, Université de

435

Escherichia coli K88 adhesion : A comparison of Chinese and Large White piglets  

E-print Network

Note Escherichia coli K88 adhesion : A comparison of Chinese and Large White piglets J.P. CHAPPUIS : K88 adhesion, E. coli, pig, genetic resistance. Résumé L'attachement de Escherichia coli K88, maintained in plastic film isolators. Shortly after successive oral inoculations of 2 E. coli strains, one K

Paris-Sud XI, Université de

436

40 CFR 96.88 - NOX allowance allocations to opt-in units.  

...allowance allocations to opt-in units. 96.88 Section 96.88...IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.88 NOX allowance allocations to opt-in units. (a) NO X allowance...source's baseline NOX emissions rate (in lb/mmBtu)...

2014-07-01

437

42 CFR 412.88 - Additional payment for new medical service or technology.  

Code of Federal Regulations, 2011 CFR

...Additional payment for new medical service or technology. 412.88 Section 412.88 Public...Cases, Special Treatment Payment for New Technology, and Payment Adjustment for Certain...Additional Special Payment for Certain New Technology § 412.88 Additional payment...

2011-10-01

438

42 CFR 412.88 - Additional payment for new medical service or technology.  

Code of Federal Regulations, 2010 CFR

...Additional payment for new medical service or technology. 412.88 Section 412.88 Public...Cases, Special Treatment Payment for New Technology, and Payment Adjustment for Certain...Additional Special Payment for Certain New Technology § 412.88 Additional payment...

2010-10-01

439

42 CFR 412.88 - Additional payment for new medical service or technology.  

Code of Federal Regulations, 2013 CFR

...Additional payment for new medical service or technology. 412.88 Section 412.88 Public...Cases, Special Treatment Payment for New Technology, and Payment Adjustment for Certain...Additional Special Payment for Certain New Technology § 412.88 Additional payment...

2013-10-01

440

42 CFR 412.88 - Additional payment for new medical service or technology.  

Code of Federal Regulations, 2012 CFR

...Additional payment for new medical service or technology. 412.88 Section 412.88 Public...Cases, Special Treatment Payment for New Technology, and Payment Adjustment for Certain...Additional Special Payment for Certain New Technology § 412.88 Additional payment...

2012-10-01

441

Production of high intensity 48Ca for the 88-Inch Cyclotron and other updates.  

PubMed

Recently the Versatile ECR for NUclear Science (VENUS) ion source was engaged in a 60-day long campaign to deliver high intensity (48)Ca(11+) beam to the 88-Inch Cyclotron. As the first long term use of VENUS for multi-week heavy-element research, new methods were developed to maximize oven to target efficiency. First, the tuning parameters of VENUS for injection into the cyclotron proved to be very different than those used to tune VENUS for maximum beam output of the desired charge state immediately following its bending magnet. Second, helium with no oxygen support gas was used to maximize the efficiency. The performance of VENUS and its low temperature oven used to produce the stable requested 75 e?A of (48)Ca(11+) beam current was impressive. The consumption of (48)Ca in VENUS using the low temperature oven was checked roughly weekly, and was found to be on average 0.27 mg/h with an ionization efficiency into the 11+ charge state of 5.0%. No degradation in performance was noted over time. In addition, with the successful operation of VENUS the 88-Inch cyclotron was able to extract a record 2 p?A of (48)Ca(11+), with a VENUS output beam current of 219 e?A. The paper describes the characteristics of the VENUS tune used for maximum transport efficiency into the cyclotron as well as ongoing efforts to improve the transport efficiency from VENUS into the cyclotron. In addition, we briefly present details regarding the recent successful repair of the cryostat vacuum system. PMID:24593540

Benitez, J Y; Franzen, K Y; Hodgkinson, A; Lyneis, C M; Strohmeier, M; Thullier, T; Todd, D; Xie, D

2014-02-01

442

Production of high intensity 48Ca for the 88-Inch Cyclotron and other updatesa)  

NASA Astrophysics Data System (ADS)

Recently the Versatile ECR for NUclear Science (VENUS) ion source was engaged in a 60-day long campaign to deliver high intensity 48Ca11+ beam to the 88-Inch Cyclotron. As the first long term use of VENUS for multi-week heavy-element research, new methods were developed to maximize oven to target efficiency. First, the tuning parameters of VENUS for injection into the cyclotron proved to be very different than those used to tune VENUS for maximum beam output of the desired charge state immediately following its bending magnet. Second, helium with no oxygen support gas was used to maximize the efficiency. The performance of VENUS and its low temperature oven used to produce the stable requested 75 e?A of 48Ca11+ beam current was impressive. The consumption of 48Ca in VENUS using the low temperature oven was checked roughly weekly, and was found to be on average 0.27 mg/h with an ionization efficiency into the 11+ charge state of 5.0%. No degradation in performance was noted over time. In addition, with the successful operation of VENUS the 88-Inch cyclotron was able to extract a record 2 p?A of 48Ca11+, with a VENUS output beam current of 219 e?A. The paper describes the characteristics of the VENUS tune used for maximum transport efficiency into the cyclotron as well as ongoing efforts to improve the transport efficiency from VENUS into the cyclotron. In addition, we briefly present details regarding the recent successful repair of the cryostat vacuum system.

Benitez, J. Y.; Franzen, K. Y.; Hodgkinson, A.; Lyneis, C. M.; Strohmeier, M.; Thullier, T.; Todd, D.; Xie, D.

2014-02-01

443

Targeted Metabolomics  

PubMed Central

The metabolome is the terminal downstream product of the genome and consists of the total complement of all the low molecular weight molecules (metabolites) in a cell, tissue or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or in disease states. Metabolomics methodologies fall into two distinct groups; untargeted metabolomics, an intended comprehensive analysis of all the measurable analytes in a sample including chemical unknowns, and targeted metabolomics, the measurement of defined groups of chemically characterized and biochemically annotated metabolites. The methodologies considered in this unit focus on the processes of conducting targeted metabolomics experiments, and the advantages of this general approach are highlighted herein. This unit outlines the procedures for extracting nitrogenous metabolites, including the amino acids, lipids, and intermediary metabolites, including the TCA cycle oxoacids, from blood plasma. Specifically, protocols for the analysis of these metabolites using liquid chromatography-mass spectrometry-based targeted metabolomics experiments is discussed. PMID:22470063

Roberts, Lee D.; Souza, Amanda L.; Gerszten, Robert E.; Clish, Clary B.

2012-01-01

444

Z-scan measurement of the ground and excited state absorption cross sections of Cr4+ in yttrium aluminum garnet  

Microsoft Academic Search

Z-scan measurements of the ground and excited state absorption cross sections of Cr4+-doped yttrium aluminum garnet are reported. These quantities are found to depend on crystal preparation but are independent of temperature from -60°C to 98°C. Their ratio is shown to weakly determine the energy output of a passively Q-switched Nd:glass laser using this material as the saturable absorber

Guohua Xiao; Jin Hong Lim; Sidney Yang; Eric Van Stryland; Michael Bass; Lou Weichman

1999-01-01

445

High Performance Ceramic Interconnect Material for Solid Oxide Fuel Cells (SOFCs): Ca- and Transition Metal-doped Yttrium Chromite  

SciTech Connect

The effect of transition metal substitution on thermal and electrical properties of Ca-doped yttrium chromite was investigated in relation to use as a ceramic interconnect in high temperature solid oxide fuel cells (SOFCs). 10 at% Co, 4 at% Ni, and 1 at% Cu substitution on B-site of 20 at% Ca-doped yttrium chromite led to a close match of thermal expansion coefficient (TEC) with that of 8 mol% yttria-stabilized zirconia (YSZ), and a single phase Y0.8Ca0.2Cr0.85Co0.1Ni0.04Cu0.01O3 remained stable between 25 and 1100 degree C over a wide oxygen partial pressure range. Doping with Cu significantly facilitated densification of yttrium chromite. Ni dopant improved both electrical conductivity and dimensional stability in reducing environments, likely through diminishing the oxygen vacancy formation. Substitution with Co substantially enhanced electrical conductivity in oxidizing atmosphere, which was attributed to an increase in charge carrier density and hopping mobility. Electrical conductivity of Y0.8Ca0.2Cr0.85Co0.1Ni0.04Cu0.01O3 at 900 degree C is 57 S/cm in air and 11 S/cm in fuel (pO2=5×10^-17 atm) environments. Chemical compatibility of doped yttrium chromite with other cell components was verified at the processing temperatures. Based on the chemical and dimensional stability, sinterability, and thermal and electrical properties, Y0.8Ca0.2Cr0.85Co0.1Ni0.04Cu0.01O3 is suggested as a promising SOFC ceramic interconnect to potentially overcome technical limitations of conventional acceptor-doped lanthanum chromites.

Yoon, Kyung J.; Stevenson, Jeffry W.; Marina, Olga A.

2011-10-15

446

Bonding mechanism of a yttrium iron garnet film on Si without the use of an intermediate layer  

NASA Astrophysics Data System (ADS)

Direct bonding of yttrium iron garnet (YIG) on silicon without the use of an intermediate bonding layer is demonstrated and characterized using scanning transmission electron microscopy and energy-dispersive x-ray spectroscopy. During the bonding experiment, the garnet is reduced in the presence of oxide-free silicon. As a result, a 5 nm thick SiO2/amorphous-YIG bilayer is formed and welds the garnet to silicon.

Pantzas, Konstantinos; Patriarche, Gilles; Talneau, Anne; Youssef, Jamal Ben

2014-10-01

447

Spectroscopic analysis of Eu3+ -and Eu3+:Yb3+-doped yttrium silicate crystalline powders prepared by combustion synthesis  

Microsoft Academic Search

Yttrium silicate powders doped with Eu3+ and codoped with Eu3+ and Yb3+ were prepared by combustion synthesis. The x-ray powder diffraction data showed the presence of Y2SiO5 and Y2Si2O7 crystalline phases. Singly doped (1 wt %) sample illuminated with ultraviolet light (lambda=256 nm) showed the characteristic red luminescence corresponding to 5D0-->7FJ transitions of Eu3+. The Judd-Ofelt intensity parameters were calculated

Nikifor Rakov; Dayanne F. Amaral; Glauco S. Maciel

2010-01-01

448

Spectroscopic analysis of Eu3+ -and Eu3+:Yb3+-doped yttrium silicate crystalline powders prepared by combustion synthesis  

Microsoft Academic Search

Yttrium silicate powders doped with Eu3+ and codoped with Eu3+ and Yb3+ were prepared by combustion synthesis. The x-ray powder diffraction data showed the presence of Y2SiO5 and Y2Si2O7 crystalline phases. Singly doped (1 wt %) sample illuminated with ultraviolet light (?=256 nm) showed the characteristic red luminescence corresponding to 5D0?7FJ transitions of Eu3+. The Judd–Ofelt intensity parameters were calculated

Nikifor Rakov; Dayanne F. Amaral; Renato B. Guimarães; Glauco S. Maciel

2010-01-01

449

Synthesis of yttrium iron garnet (YIG) by citrate–nitrate gel combustion and precursor plasma spray processes  

Microsoft Academic Search

The influence of synthesis conditions on the formation of yttrium iron garnet (YIG) powders starting from the same precursor solution was investigated by employing a citrate–nitrate (C–N) gel combustion process and a precursor plasma spraying technique. Two different C–N ratios were used in the synthesis and their influences on phase formation were studied by thermal analysis (DTA\\/TGA) and X-ray powder

X. Z. Guo; B. G. Ravi; P. S. Devi; J. C. Hanson; J. Margolies; R. J. Gambino; J. B. Parise; S. Sampath

2005-01-01

450

Influence of cyclic frequency on oxidation behavior of K38 superalloy with yttrium additions at 1 273 K  

Microsoft Academic Search

Cyclic oxidation test is a fundamental method to assess lifetime of materials in high temperature environment. Cycle length or cyclic frequency is one important variable in cyclic oxidation testing. In present work, cyclic oxidation tests were performed on cast K38 alloys with 0 wt.%, 0.1 wt.%, and 0.5 wt.% yttrium additions at 1 273 K respectively. Two cyclic frequencies were

Ping YU; Wen WANG; Fuhui WANG

2011-01-01

451

High performance ceramic interconnect material for solid oxide fuel cells (SOFCs): Ca- and transition metal-doped yttrium chromite  

NASA Astrophysics Data System (ADS)

The effect of transition metal substitution on thermal and electrical properties of Ca-doped yttrium chromite was investigated in relation to use as a ceramic interconnect in high temperature solid oxide fuel cells (SOFCs). 10 at.% Co, 4 at.% Ni, and 1 at.% Cu substitution on B-site of 20 at.% Ca-doped yttrium chromite led to a close match of thermal expansion coefficient (TEC) with that of 8 mol% yttria-stabilized zirconia (YSZ), and a single phase Y0.8Ca0.2Cr0.85Co0.1Ni0.04Cu0.01O3 remained stable between 25 and 1100 °C over a wide oxygen partial pressure range. Doping with Cu significantly facilitated densification of yttrium chromite. Ni dopant improved both electrical conductivity and dimensional stability in reducing environments, likely through diminishing the oxygen vacancy formation. Substitution with Co substantially enhanced electrical conductivity in oxidizing atmosphere, which was attributed to an increase in charge carrier density and hopping mobility. Electrical conductivity of Y0.8Ca0.2Cr0.85Co0.1Ni0.04Cu0.01O3 at 900 °C is 57 S cm-1 in air and 11 S cm-1 in fuel (pO2 = 5 × 10-17 atm) environments. Chemical compatibility of doped yttrium chromite with other cell components was verified at the processing temperatures. Based on the chemical and dimensional stability, sinterability, and thermal and electrical properties, Y0.8Ca0.2Cr0.85Co0.1Ni0.04Cu0.01O3 is suggested as a promising SOFC ceramic interconnect to potentially overcome technical limitations of conventional acceptor-doped lanthanum chromites.

Yoon, Kyung Joong; Stevenson, Jeffrey W.; Marina, Olga A.

2011-10-01

452

MyD88 signaling in brain endothelial cells is essential for the neuronal activity and glucocorticoid release during systemic inflammation.  

PubMed

Activation of neuronal circuits involved in the control of autonomic responses is critical for the host survival to immune threats. The brain vascular system plays a key role in such immune-CNS communication, but the signaling pathway and exact type of cells within the blood-brain barrier (BBB) mediating these functions have yet to be uncovered. To elucidate this issue we used myeloid differentiation factor 88 (MyD88)-deficient mice, because these animals do not show any responses to the cytokine interleukin-1beta (IL-1beta). We created chimeric mice with competent MyD88 signaling in either the BBB endothelium or perivascular microglia of bone marrow origin and challenged them with IL-1beta. Systemic treatment with the cytokine caused a robust transcriptional activation of genes involved in the prostaglandin E(2) (PGE(2)) production by vascular cells of the brain. Upregulation of these genes is dependent on a functional MyD88 signaling in the endothelium, because MyD88-deficient mice that received bone marrow stem cells from wild-type animals (for example, functional perivascular microglia) exhibited no response to systemic IL-1beta administration. MyD88 competent endothelial cells also mediate neuronal activation and plasma release of glucocorticoids, whereas chimeric mice with MyD88-competent perivascular microglia did not show a significant increase of these functions. Moreover, competent endothelial cells for the gene encoding Toll-like receptor 4 (TLR4) are essential for the release of plasma corticosterone in response to low and high doses of lipopolysaccharide. Therefore, BBB endothelial cells and not perivascular microglia are the main target of circulating inflammatory mediators to activate the brain circuits and key autonomic functions during systemic immune challenges. PMID:18180766

Gosselin, D; Rivest, S

2008-05-01

453

Effect of Yttrium Alloying on Intermediate to High-Temperature Oxidation Behavior of Mo-Si-B Alloys  

NASA Astrophysics Data System (ADS)

The oxidation behavior of 0.2 Y-alloyed Mo-9Si-8B (at. pct) was investigated in a wide temperature range from 923 K to 1673 K (650 °C to 1400 °C). Formation of a thin yttrium-silicate scale at the outer layer along with the thick silica-rich inner layer containing Y-rich oxide inclusions was detected beyond 1573 K (1300 °C). A substantial improvement in the oxidation resistance of the alloy could be realized at 1073 K to 1273 K (800 °C to 1000 °C) with the addition of yttrium. The formation of a viscous silica-rich protective scale could prevent the permeation of MoO3 at the initial stages of oxidation at this temperature regime. The growth of the internal oxidation zone followed a parabolic rate at 1273 K to 1673 K (1000 °C to 1400 °C), and the activation energy values calculated for both the outer oxide scale and internal oxidation zone formation indicated the inward diffusion of oxygen as the dominant rate controlling mechanism. The microstructural and kinetic data obtained for internal and external oxidation indicate that yttrium-silicate scale reduces the inward diffusion of oxygen, thereby improving the oxidation resistance of the alloy at high temperatures in any oxidizing environment.

Majumdar, S.; Schliephake, D.; Gorr, B.; Christ, H.-J.; Heilmaier, M.

2013-05-01

454

Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila  

PubMed Central

Innate immunity mediated by Toll signalling has been extensively studied, but how Toll signalling is precisely controlled in balancing innate immune responses remains poorly understood. It was reported that the plasma membrane localization of Drosophila MyD88 is necessary for the recruitment of cytosolic adaptor Tube to the cell surface, thus contributing to Toll signalling transduction. Here we demonstrate that Drosophila Pellino functions as a negative regulator in Toll-mediated signalling. We show that Pellino accumulates at the plasma membrane upon the activation of Toll signalling in a MyD88-dependent manner. Moreover, we find that Pellino is associated with MyD88 via its CTE domain, which is necessary and sufficient to promote Pellino accumulation at the plasma membrane where it targets MyD88 for ubiquitination and degradation. Collectively, our study uncovers a mechanism by which a feedback regulatory loop involving MyD88 and Pellino controls Toll-mediated signalling, thereby maintaining homeostasis of host innate immunity. PMID:24632597

Ji, Shanming; Sun, Ming; Zheng, Xiudeng; Li, Lin; Sun, Liwei; Chen, Dahua; Sun, Qinmiao

2014-01-01

455

Mycobacterium bovis BCG Triggered MyD88 Induces miR-124 Feedback Negatively Regulates Immune Response in Alveolar Epithelial Cells  

PubMed Central

The emerging roles of microRNAs (miRNAs) and pulmonary epithelial cells in regulating the immune response against microbial invasion has attracted increasing attention in recent years, however, the immunoregulatory roles of miRNAs in the pulmonary epithelial cells in response to mycobacterial infection has not been fully demonstrated. In this study, we show that miR-124 expression is induced upon Mycobacterium bovis Bacillus Calmette-Guerin (BCG) infection in A549 alveolar epithelial cells and murine lungs. miR-124 is able to modulate Toll-like receptor (TLR) signaling in A459 cells. In this regard, multiple components, including TLR6, myeloid differentiation factor 88 (MyD88), TNFR-associated factor 6 and tumor necrosis factor-? of the TLR signaling cascade are directly regulated by miR-124 in response to BCG stimulation. In addition, miR-124 expression was induced upon MyD88 overexpression and/or BCG stimulation, while silencing MyD88 expression by small interfering RNA dramatically down-regulated miR-124 transcription in A549 cells. These results indicate an underlying negative feedback mechanism between miR-124 and MyD88 in alveolar epithelial cells to prevent an excessive inflammatory response during mycobacterial infection. These observations suggest that miR-124 is a potential target for preventive and therapeutic intervention against the pulmonary tuberculosis, an infectious disease caused by Mycobacterium tuberculosis infection. PMID:24705038

Zeng, Jin; Wu, Xiaoling; Liu, Xiaoming; Wang, Yujiong

2014-01-01

456

RAPID COMMUNICATIONS PHYSICAL REVIEW E 88, 050802(R) (2013)  

E-print Network

node at random and attaches to this target and/or to one or more of its parents. If redirection occurs of the parent degree b [14], a rule that leads to sublinear preferential attachment network growth. In this work of networks that grow by enhanced redirection. Nodes are introduced sequentially, and each either attaches

Redner, Sidney

457

Targeting Subgroups.  

ERIC Educational Resources Information Center

By requiring limited-English-proficient students and students with disabilities to meet the same targets at the same times as all other students, the NCLB imposes a one-size-fits-all approach that ignores the individual child. Challenges school leaders to take care not to blame the students and still hold themselves accountable for continual…

Schwartzbeck, Terri Duggan

2003-01-01

458

Improved Czochralski growth and activator efficiency of cerium doped yttrium aluminum garnet by defect engineering  

NASA Astrophysics Data System (ADS)

The past several decades have seen a genuine surge in development of scintillator materials for use in a multitude of applications ranging from high energy physics to medical imaging. Despite the rapid materials discovery that has been undertaken in the search for better scintillators, a host of defects still limit scintillator performance in many promising materials. Thus the key to tapping into a scintillators full potential lies in understanding and modifying their defect structure through a process known as defect engineering. One such promising visible light scintillator is cerium doped yttrium aluminum garnet (Ce:YAG). Despite characteristics that make Ce:YAG an excellent yellow phosphor that see it commonly used in fluorescent lights and while light LEDs, performance hindering defects severely limited its potential as a bulk scintillator, a critical defect being that of UV defect luminescence. By successfully building a new Czochralski (CZ) furnace, samples could be grown with careful control over growth conditions to study and reduce these defects. All samples were grown in similar conditions by the CZ method with a (111) oriented undoped YAG seed. Several original approaches were developed in this study to reduce defects or mitigate their influence. The first method of solving the problem relied on recognizing that what many in the past identified as visible scintillation light was in fact UV defect luminescence. By using multiple photodetectors it was demonstrated that when higher cerium doping levels are involved in Ce:YAG, luminescence is not decreased due to self-absorption as previously thought, but rather UV defect emission is quenched in favor of visible emission. Once established, new avenues of research became available. Another study demonstrates Ce:YAG grown by the Czochralski method in alumina rich conditions is an effective method for reducing the number of UV producing yttrium antisite defects. This culminated in record energy resolution of Ce:YAG in a bulk sample. A final study investigated Ce:YAG grown in a rhenium crucible, both to investigate the future of high temperature oxide crystal growth, and to investigate potential benefits of Ce:YAG growth outside of an iridium crucible. The study showed significant promise in both of these categories.

Haven, Drew Thomas

459

Recovery of germanium-68 from irradiated targets  

DOEpatents

A process for selective separation of germanium-68 from proton irradiated molybdenum targets is provided and includes dissolving the molybdenum target in a hydrogen peroxide solution to form a first ion-containing solution, contacting the first ion-containing solution with a cationic resin whereby ions selected from the group consisting of molybdenum, niobium, technetium, selenium, vanadium, arsenic, germanium, zirconium and rubidium remain in a second ion-containing solution while ions selected from the group consisting of rubidium, zinc, beryllium, cobalt, iron, manganese, chromium, strontium, yttrium and zirconium are selectively adsorbed by the first resin, adjusting the pH of the second ion-containing solution to within a range of from about 0.7 to about 3.0, adjusting the soluble metal halide concentration in the second ion-containing solution to a level adapted for subsequent separation of germanium, contacting the pH-adjusted, soluble metal halide-containing second ion-containing solution with a dextran-based material whereby germanium ions are separated by the dextran-based material, and recovering the germanium from the dextran-based material, preferably by distillation.

Phillips, Dennis R. (Los Alamos, NM); Jamriska, Sr., David J. (Los Alamos, NM); Hamilton, Virginia T. (Los Alamos, NM)

1993-01-01

460

Tumor marker nucleoporin 88 kDa regulates nucleocytoplasmic transport of NF-{kappa}B  

SciTech Connect

Nucleoporin 88 kDa (Nup88) is a tumor marker, overexpressed in various types of cancer. In Drosophila Nup88 (mbo) was reported to selectively mediate the nucleocytoplasmic transport of NF-{kappa}B, an ubiquitous transcription factor involved in immune responses, apoptosis, and cancer. We addressed the function of Nup88 in mammalian cells. Selective depletion of Nup88 by small interfering RNA (siRNA) inhibited NF-{kappa}B-dependent reporter gene activation and the nuclear translocation of NF-{kappa}B without affecting the upstream activation pathway in NIH3T3 cells. In contrast, nuclear translocation of glucocorticoid receptor was not reduced by the depletion of Nup88. In metastatic melanoma cells overexpressing Nup88, constitutive activation of NF-{kappa}B was found both in nucleus and cytoplasm. Nup88 depletion in these cells reduced TNF-induced nuclear accumulation of NF-{kappa}B subunits. We conclude that Nup88 regulates the activity of NF-{kappa}B at the level of nucleocytoplasmic transport. Overexpression of Nup88 in tumor cells may, thus be involved in the constitutive NF-{kappa}B activation.

Takahashi, Nozomi [Rheumatology Research and Advanced Therapeutics, 272, NCMLS, Radboud University Medical Centre Nijmegen, P.O. Box 9101, Geert Grooteplein 26-28, 6500 HB Nijmegen (Netherlands)], E-mail: N.Takahashi@reuma.umcn.nl; Kilsdonk, Jeroen W.J. van [Department of Biomolecular Chemistry, IMM and NCMLS, Radboud University Nijmegen, 6500 HB Nijmegen (Netherlands); Ostendorf, Benedikt [Rheumatology Research and Advanced Therapeutics, 272, NCMLS, Radboud University Medical Centre Nijmegen, P.O. Box 9101, Geert Grooteplein 26-28, 6500 HB Nijmegen (Netherlands); Centre for Rheumatology, Department of Endocrinology, Diabetology and Rheumatology, Heinrich-Heine University of Duesseldorf, 40225 Duesseldorf (Germany); Smeets, Ruben [Rheumatology Research and Advanced Therapeutics, 272, NCMLS, Radboud University Medical Centre Nijmegen, P.O. Box 9101, Geert Grooteplein 26-28, 6500 HB Nijmegen (Netherlands); Bruggeman, Sophia W.M. [Department of Biomolecular Chemistry, IMM and NCMLS, Radboud University Nijmegen, 6500 HB Nijmegen (Netherlands); Netherlands Cancer Institute, 1066CX Amsterdam (Netherlands); Alonso, Angel [Deutsches Krebsforschungszentrum (DKFZ) Heidelberg, 69120 Heidelberg (Germany); Loo, Fons van de [Rheumatology Research and Advanced Therapeutics, 272, NCMLS, Radboud University Medical Centre Nijmegen, P.O. Box 9101, Geert Grooteplein 26-28, 6500 HB Nijmegen (Netherlands); Schneider, Matthias [Centre for Rheumatology, Department of Endocrinology, Diabetology and Rheumatology, Heinrich-Heine University of Duesseldorf, 40225 Duesseldorf (Germany); Berg, Wim B. van den [Rheumatology Research and Advanced Therapeutics, 272, NCMLS, Radboud University Medical Centre Nijmegen, P.O. Box 9101, Geert Grooteplein 26-28, 6500 HB Nijmegen (Netherlands); Swart, Guido W.M. [Department of Biomolecular Chemistry, IMM and NCMLS, Radboud University Nijmegen, 6500 HB Nijmegen (Netherlands)

2008-09-26

461

Target assembly  

DOEpatents

A target for a proton beam which is capable of generating neutrons for absorption in a breeding blanket includes a plurality of solid pins formed of a neutron emissive target material disposed parallel to the path of the beam and which are arranged axially in a plurality of layers so that pins in each layer are offset with respect to pins in all other layers, enough layers being used so that each proton in the beam will strike at least one pin with means being provided to cool the pins. For a 300 mA, 1 GeV beam (300 MW), stainless steel pins, 12 inches long and 0.23 inches in diameter are arranged in triangular array in six layers with one sixth of the pins in each layer, the number of pins being such that the entire cross sectional area of the beam is covered by the pins with minimum overlap of pins.

Lewis, Richard A. (Falls Church, VA)

1980-01-01

462

Acute leukemia in middle Norway 1984-88.  

PubMed

One hundred and eight adult patients with acute leukemia were diagnosed in the middle Norwegian health region during the 5-year period 1984-88, giving an incidence rate of 4.6/100,000 per year. Nine patients had acute lymphoblastic leukemia (ALL), 93 acute myeloid leukemia (AML) and 6 patients acute leukemia without definite sub-classification. The median age of AML patients was 66 years. Thirty-five patients (median age 78 years) were found non-suitable for cytotoxic drugs, while 58 AML patients (median age 57 years) were given aplasia-inducing drug combinations according to one of three treatment programs depending on the time of diagnosis and age, in order to induce remission. Six patients were given oral drugs or low dose ara-C. All patients were followed until death or for an observation time of more than 5 years (median 7 years). The overall long term survival was found to be 12/108 for all acute leukemias, 8/93 for AML patients and 4/9 for ALL patients. For the AML patients given intravenous aplasia-inducing drugs the remission rate was 0.65, the median remission duration 12.2 months and the 5-year survival rate 0.19. For 31 AML patients, (median age 41 years), started on an intensive chemotherapy program, the 5-year survival rate was 0.32 and the relapse-free 5-year survival rate for the 22 patients entering complete remission was also 0.32. PMID:7696933

Lamvik, J; Dybedal, I; Hammerstrøm, J; Waage, A

1994-12-01

463

Structure of trichosanthin at 1.88 A resolution.  

PubMed

Trichosanthin (TCS) is one of the single chain ribosome-inactivating proteins (RIPs). The crystals of the orthorhombic form of trichosanthin have been obtained from a citrate buffer (pH 5.4) with KCl as the precipitant. The crystal belongs to the space group P2(1)2(1)2(1) with a = 38.31, b = 76.22, c = 79.21 A. The structure was solved by molecular replacement method and refined using the programs XPLOR and PROLSQ to an R-factor of 0.191 for the reflections within the 6-1.88 A resolution range. The bond length and bond angle in the protein molecule have root-mean-square deviations from ideal value of 0.013 A and 3.3 degrees, respectively. The refined model includes 247 residues and 197 water molecules. The TCS molecule consists of two structural domains. The large domain contains six alpha-helices, a six-stranded sheet, and an antiparallel beta-sheet. The small domain has a largest alpha-helix, which shows a distinct bend. The possible active site of the molecule located on the cleft between two domains was proposed. In the active site Arg-163 and Glu-160, Glu-189 and Arg-122 form two ion pairs, Glu-189 and Gln-156 are hydrogen bonded to each other. Three water molecules are bonded to the residues in the active site region. The structures of TCS molecule and ricin A-chain (RTA) superimpose quite well, showing that the structures of the two protein molecules are homologous. Comparison of the structures of the TCS molecule in this orthorhombic crystal with that in the monoclinic crystal indicates that there are no essential differences of the structures between the two protein crystals. PMID:8066085

Zhou, K; Fu, Z; Chen, M; Lin, Y; Pan, K

1994-05-01

464

Structure and scintillation yield of Ce-doped Al–Ga substituted yttrium garnet  

SciTech Connect

Highlights: ? Range of Y{sub 3}(Al{sub 1?x}Ga{sub x}){sub 5}O{sub 12}:Ce solid solution crystals are grown from melt by the Czochralski method. ? Light yield of mixed crystals reaches 130% of the YAG:Ce value at x ? 0.4. ? ?1% of antisite defects is formed in YGG:Ce, but no evidence of this is obtained for the rest of crystals. -- Abstract: Structure and scintillation yield of Y{sub 3}(Al{sub 1?x}Ga{sub x}){sub 5}O{sub 12}:Ce solid solution crystals are studied. Crystals are grown from melt by the Czochralski method. Distribution of host cations in crystal lattice is determined. Quantity of antisite defects in crystals is evaluated using XRD and atomic emission spectroscopy data. Trend of light output at Al/Ga substitution in Y{sub 3}(Al{sub 1?x}Ga{sub x}){sub 5}O{sub 12}:Ce is determined for the first time. Light output in mixed crystals reaches 130% comparative to Ce-doped yttrium–aluminum garnet. Luminescence properties at Al/Ga substitution are evaluated.

Sidletskiy, Oleg, E-mail: sidletskiy@isma.kharkov.ua [Institute for Scintillation Material NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine)] [Institute for Scintillation Material NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine); Kononets, Valerii [Institute for Scintillation Material NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine); LPCML, CNRS, Université de Lyon 1, 69622 Villeurbanne Cedex (France); Lebbou, Kheirreddine [LPCML, CNRS, Université de Lyon 1, 69622 Villeurbanne Cedex (France)] [LPCML, CNRS, Université de Lyon 1, 69622 Villeurbanne Cedex (France); Neicheva, Svetlana; Voloshina, Olesya; Bondar, Valerii [Institute for Scintillation Material NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine)] [Institute for Scintillation Material NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine); Baumer, Vyacheslav; Belikov, Konstantin [SSI “Institute for Single Crystals” NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine)] [SSI “Institute for Single Crystals” NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine); Gektin, Alexander; Grinyov, Boris [Institute for Scintillation Material NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine)] [Institute for Scintillation Material NAS of Ukraine, 60 Lenin Ave., 61001 Kharkiv (Ukraine); Joubert, Marie-France [LPCML, CNRS, Université de Lyon 1, 69622 Villeurbanne Cedex (France)] [LPCML, CNRS, Université de Lyon 1, 69622 Villeurbanne Cedex (France)

2012-11-15

465

Surface-directed synthesis of erbium-doped yttrium oxide nanoparticles within organosilane zeptoliter containers.  

PubMed

We introduce an approach to synthesize rare earth oxide nanoparticles using high temperature without aggregation of the nanoparticles. The dispersity of the nanoparticles is controlled at the nanoscale by using small organosilane molds as reaction containers. Zeptoliter reaction vessels prepared from organosilane self-assembled monolayers (SAMs) were used for the surface-directed synthesis of rare earth oxide (REO) nanoparticles. Nanopores of octadecyltrichlorosilane were prepared on Si(111) using particle lithography with immersion steps. The nanopores were filled with a precursor solution of erbium and yttrium salts to confine the crystallization step to occur within individual zeptoliter-sized organosilane reaction vessels. Areas between the nanopores were separated by a matrix film of octadecyltrichlorosilane. With heating, the organosilane template was removed by calcination to generate a surface array of erbium-doped yttria nanoparticles. Nanoparticles synthesized by the surface-directed approach retain the periodic arrangement of the nanopores formed from mesoparticle masks. While bulk rare earth oxides can be readily prepared by solid state methods at high temperature (>900 °C), approaches for preparing REO nanoparticles are limited. Conventional wet chemistry methods are limited to low temperatures according to the boiling points of the solvents used for synthesis. To achieve crystallinity of REO nanoparticles requires steps for high-temperature processing of samples, which can cause self-aggregation and dispersity in sample diameters. The facile steps for particle lithography address the problems of aggregation and the requirement for high-temperature synthesis. PMID:25163977

Englade-Franklin, Lauren E; Morrison, Gregory; Verberne-Sutton, Susan D; Francis, Asenath L; Chan, Julia Y; Garno, Jayne C

2014-09-24

466

Oxidation behavior of chromium and a chromium-yttrium binary alloy  

SciTech Connect

The effect of an addition of 0.04 wt % Y on the oxidation behavior of pure Cr at 900 and 1025/sup 0/C has been investigated. The microstructures and chemical compositions of the Cr/sub 2/O/sub 3/ scales formed were studied both parallel and transverse to the oxide/metal interface by SEM, TEM, and STEM. Oxidation kinetics were measured by TGA and the direction of scale growth determined using inert markers. At 900/sup 0/C, the rate of scale growth, the direction of scale growth and the scale microstructure were unchanged by the addition of 0.04 wt % Y to Cr At 1025/sup 0/C, the direction of scale growth and scale microstructure were unchanged by the addition of 0.04 wt % Y, but the rate of oxidation was reduced by a factor of six. A model for the development of the microstructures of chromia scales formed on Cr and Cr-0.04 wt % Y is presented, and the effect of yttrium on the rate of growth of chromia at 900 and 1025/sup 0/C is discussed.

Cotell, C.M.; Przybylski, K.; Yurek, G.J.

1986-01-01

467

Power scaling of diode-pumped neodymium yttrium aluminum borate laser  

NASA Technical Reports Server (NTRS)

Preliminary results are presented of the efficient diode-pumped operation of a neodymium yttrium aluminum borate (NYAB) laser at 531.5 nm using two 1-W diode-laser arrays for the pump. With 1380 mW of CW power incident on the crystal, as much as 51 mW of 532.5-nm laser radiation was obtained with the unoptimized cavity. The corresponding optical-to-optical conversion efficiency was 3.7 percent. A plot of the output 531.5 nm vs incident 807 nm pump power is shown. The crystal output power was critically dependent on the rotational and translational adjustment of the NYAB crystal inside the cavity. It is suggested that a crystal cut at the exact phase matching angle, placed in a cavity with proper optimal reflection and transmission mirror coatings, and pumped at proper wavelength can result in higher output power. Thus, the NYAB output power approaches that of a CW intracavity frequency doubled Nd:YAG laser.

Hemmati, Hamid

1991-01-01

468

A transmission electron microscope study of hydrothermally synthesized yttrium disilicate powders  

SciTech Connect

The crystallization of three hydrothermally synthesized Y{sub 2}Si{sub 2}O{sub 7} precursor powders at temperatures between 991 and 1038 C has been studied using transmission electron microscopy. Powders prepared in acidic or near-neutral conditions were found to be highly inhomogeneous both chemically and microstructurally, with a wide range of crystalline phases formed. In contrast to this, a powder prepared in alkaline conditions was found to be very homogeneous. Small crystalline nuclei were formed in this powder on heating to 1006 C which grew rapidly at 1038 C to form large single crystal particles. The majority of these had the {alpha}-Y{sub 2}Si{sub 2}O{sub 7} phase but some were of the y-Y{sub 2}Si{sub 2}O{sub 7} phase. The reasons for the formation of this y-phase are unclear, although it would be expected to transform to {alpha}-Y{sub 2}Si{sub 2}O{sub 7} on further heat treatment at 1200 C. Weaknesses in the current crystal structure data for yttrium disilicate phases are identified and suggestions made for rectifying them.

MacLaren, I.; Trusty, P.A.; Ponton, C.B. [Univ. of Birmingham, Edgbaston (United Kingdom)] [Univ. of Birmingham, Edgbaston (United Kingdom)

1999-02-05

469

Structure and dynamics in yttrium-based molten rare earth alkali fluorides  

E-print Network

The transport properties of molten LiF-YF3 mixtures have been studied by pulsed field gradient nuclear magnetic resonance spectroscopy, potentiometric experiments, and molecular dynamics simulations. The calculated diffusion coefficients and electric conductivities compare very well with the measurements accross a wide composition range. We then extract static (radial distribution functions, coordination numbers distributions) and dynamic (cage correlation functions) quantities from the simulations. Then, we discuss the interplay between the microscopic structure of the molten salts and their dynamic properties. It is often considered that variations in the diffusion coefficient of the anions are mainly driven by the evolution of its coordination with the metallic ion (Y3+ here). We compare this system with fluorozirconate melts and demonstrate that the coordination number is a poor indicator of the evolution of the diffusion coefficient. Instead, we propose to use the ionic bonds lifetime. We show that the weak Y-F ionic bonds in LiF-YF3 do not induce the expected tendency of the fluoride diffusion coefficient to converge toward the one of yttrium cation when the content in YF3 increases. Implications on the validity of the Nernst-Einstein relation for estimating the electrical conductivity are discussed.

Maximilien Levesque; Vincent Sarou-Kanian; Mathieu Salanne; Mallory Gobet; Henri Groult; Catherine Bessada; Paul A. Madden; Anne-Laure Rollet

2013-02-19

470

Structural and spectroscopic analyses of europium doped yttrium oxyfluoride powders prepared by combustion synthesis  

NASA Astrophysics Data System (ADS)

A facile widely spread technique employed to produce low-cost high-yield oxide powders, combustion synthesis, was used to prepare yttrium oxyfluoride crystalline ceramic powders. The structure of the powders was analyzed by X-ray powder diffraction and Rietveld refinement. Samples heat treated at 700 °C had a predominance of vernier orthorhombic Y6O5F8 phase, while samples heat treated at 800 °C crystallized in stoichiometric rhombohedral YOF phase. The samples were doped with luminescent europium trivalent ions (Eu3+) in different concentrations (1-15 wt.%) and Judd-Ofelt theory was used to probe the distortion from the inversion symmetry of the local crystal field and the degree of covalency between the rare-earth ion and the surrounding ligands. The luminescence lifetime was measured and the luminescence quantum efficiency (LQE) was estimated. We observed that Eu3+:Y6O5F8 samples presented higher LQE in spite of the larger local crystal field anisotropy found for Eu3+:YOF samples.

Rakov, Nikifor; Guimarães, R. B.; Lozano B., W.; Maciel, Glauco S.

2013-07-01

471

Light desorption from an yttrium neutralizer for Rb and Fr magneto-optical trap loading  

NASA Astrophysics Data System (ADS)

We present here the first evidence of photodesorption induced by low-intensity non-resonant light from an yttrium thin foil, which works as a neutralizer for Rb and Fr ions beam. Neutral atoms are suddenly ejected from the metal surface in a pulsed regime upon illumination with a broadband flash light and then released in the free volume of a pyrex cells. Here atoms are captured by a Magneto-Optical Trap (MOT), which is effectively loaded by the photodesorption. Loading times of the order of the flash rise time are measured. Desorption is also obtained in the continuous regime, by exploiting CW visible illumination of the metallic neutralizer surface. We demonstrate that at lower CW light intensities vacuum conditions are not perturbed by the photodesorption and hence the MOT dynamics remains unaffected, while the trap population increases thanks to the incoming desorbed atoms flux. Even with the Y foil at room temperature and hence with no trapped atoms, upon visible illumination, the number of trapped atoms reaches 105. The experimental data are then analyzed by means of an analytical rate equation model, which allows the analysis of this phenomenon and its dynamics and allows the determination of critical experimental parameters and the test of the procedure in the framework of radioactive Francium trapping. In this view, together with an extensive investigation of the phenomenon with 85Rb, the first demonstration of the photodesorption-aided loading of a 210Fr MOT is shown.

Coppolaro, V.; Papi, N.; Khanbekyan, A.; Marinelli, C.; Mariotti, E.; Marmugi, L.; Moi, L.; Corradi, L.; Dainelli, A.; Arikawa, H.; Ishikawa, T.; Sakemi, Y.; Calabrese, R.; Mazzocca, G.; Tomassetti, L.; Ricci, L.

2014-10-01

472

Synthesis of Eu3+ doped yttrium orthosilicate phosphor by sol-combustion method  

NASA Astrophysics Data System (ADS)

Eu3+ doped yttrium orthosilicate (Y2SiO5) phosphor was prepared by the sol-combustion method using citric acid as complexing agent in this experiment. The X-ray diffraction (XRD) pattern, excitation and emission spectra were used to investigate the crystal structure and luminescent properties of the phosphor. XRD pattern showed that pure Y2SiO5:Eu3+ phosphor was obtained. The excitation spectrum was composed of a broad band from 200-350 nm and a series of narrow bands from 350-500 nm, in which the excitation peaks at 400 nm and 470 nm were stronger. The emission spectrum showed the most intense emission peak was located at 613 nm, which corresponded to the 5D0-->7F2 transition of Eu3+. The results showed that this phosphor could be excited by UV or blue light and emit red light. The luminescent intensity depends on the concentration of Eu3+ and it reached the maximum when the molar concentration of Eu3+ was 4 mol%. In this study, we found that the emission intensity reached maximum when the ratio of citric acid and Y3+ was 1.5:1. The results indicated that Y2SiO5:Eu3+ is a potential red-emitting candidate phosphor for white light-emitting diodes.

Guan, Li; Jin, Litao; Jia, Guoqi; Li, Xu; Yang, Zhiping; Guo, Qinglin; Fu, Guangsheng

2010-11-01

473

Electronic structure, vibrational spectrum, and thermal properties of yttrium nitride: A first-principles study  

NASA Astrophysics Data System (ADS)

Yttrium nitride (YN) is a promising semiconductor for use in metal/semiconductor superlattices for thermoelectric applications. We determine its electronic structure, vibrational spectrum, and thermal properties using first-principles density functional theory (DFT) based simulations with a generalized gradient approximation (GGA) of the exchange correlation energy. We employ GGA+U and GW approximations in our calculations to (a) improve the accuracy of the calculation of bandgaps and (b) determine specific features of its electronic structure relevant to transport properties, such as transverse (mt*) and longitudinal (m1*) conduction band effective mass. To evaluate consequences of forming alloys of YN with other materials to its electronic properties, we have determined the volume deformation potentials. Our results for phonons show a large longitudinal optical (LO) and transverse optical (TO) splitting at the ? point in the vibrational spectrum with a gap of 325 cm-1 arising from long- range dipole-dipole interactions. We estimate temperature dependent lattice specific heat and lattice thermal conductivity based on Boltzmann transport theory to assess YN's potential for thermoelectric applications.

Saha, Bivas; Sands, Timothy D.; Waghmare, Umesh V.

2011-04-01

474

Induced Magneto-transport Effects in Non-magnetic Metals on Yttrium Iron Garnet  

NASA Astrophysics Data System (ADS)

Yttrium iron garnet (YIG) was called ``spin Seebeck insulator,'' for it supports heat-generated pure spin currents. Pt thin film, with strong spin-orbit interaction, is used as a spin current generator or detector based on the spin Hall effect or the inverse spin Hall effect. The combination of these two materials plays a very important role in spintronics. A recent magnetotransport study shows strong evidence of a magnetic proximity effect in thin Pt films deposited on YIG. Here, we present a magneto-transport study of several non-magnetic (NM) metal films (e.g. Pt, Pd) on YIG films grown on gadolinium gallium garnet substrates with laser molecular beam epitaxy. The anisotropic magnetoresistance (AMR) and anomalous Hall effect (AHE) reveal clear ferromagnetic characteristics in NM films. The magnitude of the AHE angle ? in Pd/YIG structure increases with decreasing temperature, while ? in Pt/YIG structure has a sign reversal at an intermediate temperature. Both AMR and AHE have been investigated as the NM film thickness is varied and an optimal effective thickness is identified. The effect of annealing has also been studied and the results are consistent with the observed thickness dependence. In thin NM films, a ln(T) temperature dependence with a resistivity minimum is observed at low temperatures, suggesting that the Kondo effect may be relevant. Detailed discussions about the origin of these effects will be presented.

Lin, Tao; Tang, Chi; Shi, Jing

2013-03-01

475

Effect of Yttrium Doping in Barium Zirconium Titanate Ceramics: A Structural, Impedance, and Modulus Spectroscopy Study  

NASA Astrophysics Data System (ADS)

In the current article, we studied the effect of yttrium [Y3+] ions' substitution on the structure and electric behavior of barium zirconate titanate (BZT) ceramics with a general formula [Ba1- x Y2 x/3](Zr0.25Ti0.75)O3 (BYZT) with [ x = 0, 0.025, and 0.05] which were prepared by the solid-state reaction method. X-ray diffraction patterns indicate that these ceramics have a single phase with a perovskite-type cubic structure. Rietveld refinement data confirmed [BaO12], [ZrO6], [TiO6], and [YO6] clusters in the cubic lattice. The Y3+ ions' effects on the electric conductivity behavior of BZT ceramics as a function of temperature and frequency are described, which are based on impedance spectroscopy analyses. The complex impedance plots display a double semicircle which highlights the influences of grain and grain boundary on the ceramics. Impedance analyses showed that the resistance decreased with the increasing temperature and resulted in a negative temperature coefficient of the resistance property in all compositions. Modulus plots represent a non-Debye-type dielectric relaxation which is related to the grain and grain boundary as well as temperature-dependent electric relaxation phenomenon and an enhancement in the mobility barrier by Y3+ ions. Moreover, the electric conductivity increases with the replacement of Ba2+ by Y3+ ions may be due to the rise in oxygen vacancies.

Badapanda, Tanmaya; Cavalcante, Laécio Santos; da Luz, Geraldo Eduardo; Batista, Nouga Cardoso; Anwar, Shahid; Longo, Elson

2013-09-01

476

A study of Au adsorption on yttrium disilicide nanowires on Si (001) substrate from first principles  

NASA Astrophysics Data System (ADS)

Core-shell nanoclusters with Au coating layer on uniformly dispersed rear-earth disilicide nanowires are very promising for various applications such as nanocatalysis. Using the first principles approach, we studied the structure and electronic properties of a single Au atatom on yttrium disilicide nanowires on the Si(100) substrate. A series of possible adsorption sites were explored and we found that the ``hollow'' site on the YSi2 nanowire is the most preferential one, where the Au adatom binds to two Si atoms and an Y atom underneath. The most stable site for Au on Si(001) is the ``cave'' site, but the binding energy is 0.11 eV higher than that on the wire. This indicates that the Au atoms tend to aggregate toward nanowires, which leads to growth of core-shell metallic structures. Electrons deplete from Au adatom and accumulated in regions between Au and Si. The chemical activity of Au/YSi2 will be discussed in light of charge density, density of states and adsorption energy of CO molecules.

Ouyang, Wenjie; Shinde, Aniketa; Cao, Juexian; Wu, Ruqian

2010-03-01

477

Grain growth and microstructural evolution of yttrium aluminum garnet nanocrystallites during calcination process  

SciTech Connect

An yttrium aluminum garnet (YAG) precursor precipitate was synthesized by urea method using yttria (Y{sub 2}O{sub 3}) and aluminum nitrate (Al(NO{sub 3}){sub 3}.9H{sub 2}O) as raw materials. The fresh wet precipitate was dried by supercritical carbon dioxide (CO{sub 2}) fluid and the resulting powder was calcined at temperatures from 600 to 1600 {sup o}C. Crystallization of YAG was detected at 800 {sup o}C, and completed at 900 {sup o}C. HRTEM images of the YAG product obtained above 900 {sup o}C revealed crystallographically specific oriented attachment along the [1 1 2] direction. Based on the observation of the particle morphology a possible growth mechanism of YAG nanoparticles was presented. The fast increase on the average crystallite size of YAG at temperatures from 900 to 1300 {sup o}C is attributed to the crystallographically specific oriented attachment growth process. As the growth process proceeds at higher temperatures, oriented attachment based growth becomes less important because of the increase on particle size, and the self-integration assisted by the Ostwald ripening becomes dominant.

Qin, Jie [State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029 (China)] [State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029 (China); Yang, Ru, E-mail: yangru@bbn.cn [State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029 (China)] [State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029 (China); Liu, Guoqiang; Li, Min [State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029 (China)] [State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029 (China); Shi, Yongxi [Colleges of Science, Beijing University of Chemical Technology, Beijing, 100029 (China)] [Colleges of Science, Beijing University of Chemical Technology, Beijing, 100029 (China)

2010-10-15

478

Determination of yttrium iron garnet superexchange parameters as a function of oxygen and cation stoichiometry  

NASA Astrophysics Data System (ADS)

In this work, we describe the consequences of oxygen and metal-ion deficiency for the magnetic properties of a magnetic oxide in bulk and thin-film form. The influence of the off stoichiometry on valence of the iron atoms and the local structural configuration of these atoms is investigated in correlation with the magnetic Curie temperatures and the associated microscopic parameters, such as the exchange integrals. Combining both structural information obtained by x-ray absorption spectroscopy at FeK edge and exchange integrals as determined from temperature-resolved magneto-optical magnetometry, we show that the electron-transfer integrals, underlying the superexchange interaction, control the global dependence of the Curie temperature on stoichiometry as should be expected. The determination of the electron-transfer integrals allows also the confirmation that metal-ion deficiencies in off-stoichiometric yttrium iron garnet (OS YIG) films lead to a significant increase in the magnetization (as observed experimentally). That can only be explained when considering a preferential site occupation of the iron vacancies on octahedral sites in agreement with our earlier work on OS YIG films [Y. Dumont , Phys. Rev. B 76, 6 (2007)]. Furthermore, the combination of the experimentally determined iron valence with the Fea-O-Fed bonding angle and the exchange integrals allows for the direct determination of the crystal electric field parameter and the Coulomb repulsion energy as a function of the stoichiometry of the YIG films.

Noun, W.; Popova, E.; Bardelli, F.; Dumont, Y.; Bertacco, R.; Tagliaferri, A.; Tessier, M.; Guyot, M.; Berini, B.; Keller, N.

2010-02-01

479

Patient Selection and Activity Planning Guide for Selective Internal Radiotherapy With Yttrium-90 Resin Microspheres  

SciTech Connect

Purpose: Selective internal radiotherapy (SIRT) with yttrium-90 ({sup 90}Y) resin microspheres can improve the clinical outcomes for selected patients with inoperable liver cancer. This technique involves intra-arterial delivery of {beta}-emitting microspheres into hepatocellular carcinomas or liver metastases while sparing uninvolved structures. Its unique mode of action, including both {sup 90}Y brachytherapy and embolization of neoplastic microvasculature, necessitates activity planning methods specific to SIRT. Methods and Materials: A panel of clinicians experienced in {sup 90}Y resin microsphere SIRT was convened to integrate clinical experience with the published data to propose an activity planning pathway for radioembolization. Results: Accurate planning is essential to minimize potentially fatal sequelae such as radiation-induced liver disease while delivering tumoricidal {sup 90}Y activity. Planning methods have included empiric dosing according to degree of tumor involvement, empiric dosing adjusted for the body surface area, and partition model calculations using Medical Internal Radiation Dose principles. It has been recommended that at least two of these methods be compared when calculating the microsphere activity for each patient. Conclusions: Many factors inform {sup 90}Y resin microsphere SIRT activity planning, including the therapeutic intent, tissue and vasculature imaging, tumor and uninvolved liver characteristics, previous therapies, and localization of the microsphere infusion. The influence of each of these factors has been discussed.

Lau, Wan-Yee, E-mail: josephlau@surgery.cuhk.edu.hk [Faculty of Medicine, Chinese University of Hong Kong, Shatin, New Territories (Hong Kong); Kennedy, Andrew S. [Wake Radiology Oncology, Cary, NC (United States); Department of Biomedical Engineering, North Carolina State University, Raleigh, NC (United States); Kim, Yun Hwan [Department of Radiology, Anam Hospital, Korea University College of Medicine, Seoul (Korea, Republic of); Lai, Hee Kit [Nuclear Medicine and PET Centre, Mount Elizabeth Hospital, Singapore (Singapore); Lee, Rheun-Chuan [Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan (China); Leung, Thomas W.T. [Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital (Hong Kong); Liu, Ching-Sheng [Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan (China); Salem, Riad [Division of Interventional Radiology, Northwestern University, Chicago, IL (United States); Sangro, Bruno [Liver Unit, Clinica Universitaria de Navarra and Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas, Pamplona (Spain); Shuter, Borys [Department of Diagnostic Imaging, National University Hospital, Singapore (Singapore); Wang, Shih-Chang [Parker-Hughes Professor of Diagnostic Radiology, University of Sydney, Sydney, NSW (Australia)

2012-01-01

480

Chiral bis(phthalocyaninato) yttrium double-decker complexes. Synthesis, structure, spectroscopy, and electrochemistry.  

PubMed

Two new chiral sandwich-type bis(phthalocyaninato) yttrium double-decker complexes including the homoleptic species (R)- and (S)-Y[Pc(OBNP)4]2 (1) and a heteroleptic analogue (R)- and (S)-Y(Pc)[Pc(OBNP)4] (2) {Pc = unsubstituted phthalocyaninate; [Pc(OBNP)4] = tetrakis(dinaphtho[1,2-e:1',2'-g]-1,4-(dioxocine)[2,3-b;2',3'-k;2'',3''-t;2''',3'''-c']phthalocyaninate)} have been synthesized and spectroscopically characterized. In particular, the molecular structures of (R)- and (S)-1 were determined on the basis of single crystal X-ray diffraction analysis, representing the first structurally characterized chiral bis(phthalocyaninato) rare earth double-decker complexes. Perfect mirror-image CD signals observed in the whole phthalocyanine absorption range of the CD spectra of the (R)- and (S)-enantiomers for both compounds reveal the effective chiral information transfer from the peripheral binaphthyl moieties to the phthalocyanine chromophore, while the difference observed in the CD spectrum between 1 and 2 indicates the effect of the chiral substituent number on the chiral information transfer. Nevertheless, the absolute structures unambiguously elucidated for both enantiomers of the homoleptic double-decker render it possible to clarify the chirality of optically active bis(phthalocyaninato) rare earth compounds. PMID:24225848

Zhou, Hang; Wang, Kang; Qi, Dongdong; Jiang, Jianzhuang

2014-01-28

481

Radiopharmaceuticals for radiation synovectomy: Evaluation of two yttrium-90 particulate agents  

SciTech Connect

Radiation synovectomy, a noninvasive therapeutic alternative to surgical synovectomy, has not gained widespread acceptance in the United States because of the lack of a suitable radiopharmaceutical. Two new radioactive particles, (/sup 90/Y)Ca oxalate and (/sup 90/Y)ferric hydroxide macroaggregates (FHMA), were developed in our laboratory and evaluated for size, stability, and joint leakage. More than 90% of the (/sup 90/Y)Ca oxalate particles were in the optimal size range of 1-10 microns, and the unbound activity in serum and synovial fluid was 3.7% to 5.0%. Following injection in rabbit knees, leakage of (/sup 90/Y)Ca oxalate was 5 +/- 2%, with localization primarily in the bone and virtually no uptake by the lymph nodes or liver. Yttrium-90 FHMA particles were larger (95% greater than 10 microns), and at least on a microscopic level, appeared to distribute homogeneously over the articular surface. Leakage of (/sup 90/Y)FHMA was initially less but eventually slightly exceeded that of (/sup 90/Y)Ca oxalate. Nevertheless, both radiopharmaceuticals can provide a satisfactory therapeutic dose to the knee with less than half the leakage and a marked reduction in absorbed dose to nontarget tissues compared to previously tested agents. Ease of preparation, physical characteristics of the /sup 90/Y beta ray, and apparent lack of substantial leakage from the joint make these agents extremely attractive for clinical evaluation in rheumatoid arthritis patients who are unresponsive to medical therapy.

Davis, M.A.; Chinol, M.

1989-06-01

482

Efficient eye-safe neodymium doped composite yttrium gallium garnet crystal laser.  

PubMed

We report a laser-diode pumped continuous-wave (cw) and passively Q-switched eye-safe laser at about 1.42 ?m with the neodymium-doped yttrium gallium garnet (Nd:YGG) crystal for the first time to our knowledge. The composite Nd:YGG crystal was developed originally. A systematic comparison of laser performance between the homogeneously doped and composite Nd:YGG crystal was made, which showed that the composite Nd:YGG manifested less thermally induced effects. Cw output power of 2.06 W was obtained with the slope efficiency of 20.7%. With a V:YAG as a saturable absorber, the passive Q-switching at 1.42 ?m was gotten with the pulse width, pulse energy, and peak power of 34 ns, 46.7 ?J, and 1.4 kW, respectively. The present work should provide a potential candidate for the generation of eye-safe lasers. PMID:24690782

Yu, Haohai; Wang, Shuxian; Han, Shuo; Wu, Kui; Su, Liangbi; Zhang, Huaijin; Wang, Zhengping; Xu, Jun; Wang, Jiyang

2014-03-15

483

Structural and spectroscopic analyses of europium doped yttrium oxyfluoride powders prepared by combustion synthesis  

SciTech Connect

A facile widely spread technique employed to produce low-cost high-yield oxide powders, combustion synthesis, was used to prepare yttrium oxyfluoride crystalline ceramic powders. The structure of the powders was analyzed by X-ray powder diffraction and Rietveld refinement. Samples heat treated at 700 °C had a predominance of vernier orthorhombic Y{sub 6}O{sub 5}F{sub 8} phase, while samples heat treated at 800 °C crystallized in stoichiometric rhombohedral YOF phase. The samples were doped with luminescent europium trivalent ions (Eu{sup 3+}) in different concentrations (1–15 wt.%) and Judd-Ofelt theory was used to probe the distortion from the inversion symmetry of the local crystal field and the degree of covalency between the rare-earth ion and the surrounding ligands. The luminescence lifetime was measured and the luminescence quantum efficiency (LQE) was estimated. We observed that Eu{sup 3+}:Y{sub 6}O{sub 5}F{sub 8} samples presented higher LQE in spite of the larger local crystal field anisotropy found for Eu{sup 3+}:YOF samples.

Rakov, Nikifor [PG-Ciência dos Materiais, Universidade Federal do Vale do São Francisco, 48902-300 Juazeiro, BA (Brazil)] [PG-Ciência dos Materiais, Universidade Federal do Vale do São Francisco, 48902-300 Juazeiro, BA (Brazil); Guimarães, R. B.; Maciel, Glauco S. [Instituto de Física, Universidade Federal Fluminense, 24210-346 Niterói, RJ (Brazil)] [Instituto de Física, Universidade Federal Fluminense, 24210-346 Niterói, RJ (Brazil); Lozano B, W. [Departamento de Física, Universidade Federal de Pernambuco, 50670-901 Recife, PE (Brazil)] [Departamento de Física, Universidade Federal de Pernambuco, 50670-901 Recife, PE (Brazil)

2013-07-28

484

Tuning the architecture and properties of microstructured yttrium tungstate oxide hydroxide and lanthanum tungstate.  

PubMed

In this paper, various microstructures of yttrium and lanthanum tungstates were synthesized under hydrothermal conditions, at pH 5, in a ligand-free environment, and in the presence of a dioctyl sodium sulfosuccinate (DSS) surfactant. It was observed that the shape of the nanobuilding blocks, and therefore the architecture of the microstructures, could be tuned by controlling the reaction conditions, such as the source of the rare earth, the amount of a surfactant and the reaction time. X-ray powder diffraction (XRD), elemental analysis, scanning electron microscopy (SEM), and N2 adsorption were employed to characterize the obtained products. The photoluminescent properties of Eu(3+) and Dy(3+) doped tungstate materials were investigated. Luminescence measurements showed an efficient charge transfer from the WO4(2-) groups to Eu(3+) and Dy(3+) ions. It was found that under UV excitation the Dy(3+) doped Y(WO3)2(OH)3 and La2(WO4)3 precursors exhibit white emission. PMID:23426044

Kaczmarek, Anna M; Liu, Ying-Ya; Van der Voort, Pascal; Van Deun, Rik

2013-04-21

485

Light desorption from an yttrium neutralizer for Rb and Fr magneto-optical trap loading.  

PubMed

We present here the first evidence of photodesorption induced by low-intensity non-resonant light from an yttrium thin foil, which works as a neutralizer for Rb and Fr ions beam. Neutral atoms are suddenly ejected from the metal surface in a pulsed regime upon illumination with a broadband flash light and then released in the free volume of a pyrex cells. Here atoms are captured by a Magneto-Optical Trap (MOT), which is effectively loaded by the photodesorption. Loading times of the order of the flash rise time are measured. Desorption is also obtained in the continuous regime, by exploiting CW visible illumination of the metallic neutralizer surface. We demonstrate that at lower CW light intensities vacuum conditions are not perturbed by the photodesorption and hence the MOT dynamics remains unaffected, while the trap population increases thanks to the incoming desorbed atoms flux. Even with the Y foil at room temperature and hence with no trapped atoms, upon visible illumination, the number of trapped atoms reaches 10(5). The experimental data are then analyzed by means of an analytical rate equation model, which allows the analysis of this phenomenon and its dynamics and allows the determination of critical experimental parameters and the test of the procedure in the framework of radioactive Francium trapping. In this view, together with an extensive investigation of the phenomenon with (85)Rb, the first demonstration of the photodesorption-aided loading of a (210)Fr MOT is shown. PMID:25296799

Coppolaro, V; Papi, N; Khanbekyan, A; Marinelli, C; Mariotti, E; Marmugi, L; Moi, L; Corradi, L; Dainelli, A; Arikawa, H; Ishikawa, T; Sakemi, Y; Calabrese, R; Mazzocca, G; Tomassetti, L; Ricci, L

2014-10-01

486

Structure and spectroscopic properties of oxygen divacancy in yttrium-stabilized zirconia  

NASA Astrophysics Data System (ADS)

We have studied the structure and spectroscopic properties of the oxygen divacancy defect in Yttrium-stabilized ZrO2 using periodic and embedded cluster methods and GGA and B3LYP density functionals. The results demonstrate that the defect spectroscopic properties depend on the particular arrangement of Y dopants near vacancies. The optical transition energies calculated for the negatively charged state of the divacancy at 2.8 eV and 3.3 eV are in agreement with experimental data. The second set of transitions between 1.9 eV and 2.7 eV corresponds to the electron transfer between vacancies. The calculated EPR g-tensor values are in agreement with other works. The results support the proposed attribution of the optical absorption peaking at 3.3 eV and related EPR spectra to Zr3+ ions in the YSZ matrix, however, they are not fully conclusive due to dependence on Y concentration.

Ramo, D. M.; Shluger, A. L.

2008-06-01

487

Yttrium recovery from primary and secondary sources: a review of main hydrometallurgical processes.  

PubMed

Yttrium is important rare earths (REs) used in numerous fields, mainly in the phosphor powders for low-energy lighting. The uses of these elements, especially for high-tech products are increased in recent years and combined with the scarcity of the resources and the environmental impact of the technologies to extract them from ores make the recycling waste, that contain Y and other RE, a priority. The present review summarized the main hydrometallurgical technologies to extract Y from ores, contaminated solutions, WEEE and generic wastes. Before to discuss the works about the treatment of wastes, the processes to retrieval Y from ores are discussed, since the processes are similar and derived from those already developed for the extraction from primary sources. Particular attention was given to the recovery of Y from WEEE because the recycle of them is important not only for economical point of view, considering its value, but also for environmental impact that this could be generated if not properly disposal. PMID:24613592

Innocenzi, Valentina; De Michelis, Ida; Kopacek, Bernd; Vegliò, Francesco

2014-07-01

488

Radiographic Parameters in Predicting Outcome of Patients with Hepatocellular Carcinoma Treated with Yttrium-90 Microsphere Radioembolization  

PubMed Central

Background. In patients with hepatocellular carcinoma, selection criteria for transarterial hepatic selective internal radiotherapy are imprecise. Additionally, radiographic parameters to predict outcome of transarterial hepatic selective internal radiotherapy have not been fully characterized. Patients and methods. Computed tomography (CT) scans of 23 patients with unresectable primary hepatocellular carcinoma before and after transarterial hepatic selective internal radiotherapy with yttrium-90 microspheres were retrospectively reviewed. Selected radiographic parameters were evaluated and correlated with progression-free survival and overall survival. Response to treatment was assessed with Response RECIST 1.1 and Morphology, Attenuation, Size, and Structure (MASS) criteria. Results. On the post-SIRT CT, 68% of tumors demonstrated decreased size (median decrease of 0.8?cm, P = 0.3); 64% had decreased attenuation (median decrease 5.7?HU, P = 0.06), and 48% demonstrated increased tumor necrosis (P < 0.001). RECIST-defined partial response was seen in 10% patients, stable disease in 80%, and 10% had disease progression. Median progression-free survival was 3.9 months (range, 3.3 to 7.3), and median overall survival was 11.2 months (7.1 to 31.1). Pretreatment lower hepatopulmonary shunt fraction, central hypervascularity, and well-defined tumor margins were associated with improved progression-free survival. Conclusion. In patients with unresectable hepatocellular carcinoma, pretreatment CT parameters may predict favorable response to SIRT and improve patient selection. PMID:24167742

Salem, Mohamed E.; Dyson, Gregory; El-Refai, Sherif M.; Choi, Minsig; Shields, Anthony F.; Critchfield, Jeffery; Philip, Philip A.

2013-01-01

489

MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus.  

PubMed

MyD88 is a key adaptor molecule in innate resistance, engaged in most Toll-like receptor, as well as IL-1 and IL-18, signalling. Here, w