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Sample records for 0450-2958 scantily dressed

  1. THE QSO HE 0450-2958: SCANTILY DRESSED OR HEAVILY ROBED? A NORMAL QUASAR AS PART OF AN UNUSUAL ULIRG

    SciTech Connect

    Jahnke, Knud; Elbaz, David; Pantin, Eric; Lagage, Pierre-Olivier; Letawe, Geraldine; Chantry, Virginie

    2009-08-01

    The luminous z = 0.286 quasar HE 0450-2958 is interacting with a companion galaxy at 6.5 kpc distance and the whole system radiates in the infrared (IR) at the level of an ultraluminous infrared galaxy (ULIRG). A so far undetected host galaxy triggered the hypothesis of a mostly 'naked' black hole (BH) ejected from the companion by three-body interaction. We present new Hubble Space Telescope (HST)/NICMOS 1.6 {mu}m imaging data at 0.''1 resolution and VLT/VISIR 11.3 {mu}m images at 0.''35 resolution that are for the first time resolving the system in the near- and mid-infrared. We combine these data with existing optical HST and CO maps. (1) At 1.6 {mu}m we find an extension NE of the quasar nucleus that is likely a part of the host galaxy, though not its main body. If true, a combination with upper limits on a main body co-centered with the quasar brackets the host-galaxy luminosity to within a factor of {approx}4 and places HE 0450-2958 directly onto the M{sub BH} - M{sub bulge} relation for nearby galaxies. (2) A dust-free line of sight to the quasar suggests a low dust obscuration of the host galaxy, but the formal upper limit for star formation (SF) lies at 60 M{sub sun} yr{sup -1}. HE 0450-2958 is consistent with lying at the high-luminosity end of Narrow-Line Seyfert 1 Galaxies, and more exotic explanations like a 'naked quasar' are unlikely. (3) All 11.3 {mu}m radiation in the system is emitted by the quasar nucleus. It has warm ULIRG-strength IR emission powered by BH accretion and is radiating at super-Eddington rate, L/L{sub Edd} = 6.2{sup +3.8}{sub -1.8}, or 12 M{sub sun} yr{sup -1}. (4) The companion galaxy is covered in optically thick dust and is not a collisional ring galaxy. It emits in the far-infrared at ULIRG strength, powered by Arp220-like SF (strong starburst-like). An M82-like SED is ruled out. (5) With its BH accretion rate, HE 0450-2958 produces not enough new stars to maintain its position on the M{sub BH} - M{sub bulge} relation, and SF

  2. [DRESS syndrome].

    PubMed

    Adamcová, Monika; Šturdík, Igor; Koller, Tomáš; Payer, Juraj

    2016-04-01

    DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is severe drug-induced allergic-type reaction which occurs few days to weeks after taking a drug in a predisposed patient. Organ damage, eosinophilia and skin rash are typical at presentation. Corticotherapy is often necessary in severe cases. In this report we describe a case of 56-year old female with fever, elevated liver tests and skin rash. DRESS syndrome was diagnosed and allopurinol was indentified as a causative drug. Due to possible fatal outcome, DRESS syndrome should be considered in a differential diagnosis of all patients presenting with similar signs and symptoms. PMID:27250614

  3. Sources and Mechanisms of Aquifer Recharge: a Hydrochemical and Isotopic Study in a Complex and Scantily Investigated Hydrogeologic System

    NASA Astrophysics Data System (ADS)

    Damtew, A. D.; Wohnlich, S.

    2013-12-01

    Over 90% of domestic water supply in the study area is tapped from shallow and deep aquifers. However, sources and mechanisms of recharge that sustain these aquifers in the area are scantily researched. To understand aquifer recharge processes in this complex geo-hydrologic environment which is confined within the southern sector of the Main Ethiopian Rift, interpretations on the hydrochemical, stable and unstable isotope constituents of waters, in conjunction with some of the basin attributes that influence on the processes of aquifer recharge are made. The study reveals meteoric sources as the main source of aquifer recharge, and complex mechanisms of recharge in the different zones of the study area. Low salinity warm waters drawn from deep aquifers around the northwestern part of the area plotted close to the Local Meteoric Water Line are replenished via local normal faults. The confined aquifers in the northern part with the characteristics of high salinity, warm, isotopically depleted waters sourced from areas less affected by rift faults, replenished by regional recharge from distant western highlands, however, recharge is considered as modern as the tritium levels in those waters signify post bomb origin. Deep aquifers around the north-eastern and the north-central parts of the study area bear isotopically depleted and cold waters. These areas are characterized by low to very low drainage density and fracture density, gentle slope, covered dominantly by unwelded tuffs, pumaceous deposits, and fractured ignimbrites. Aquifer recharge in this particular zone may occur after heavy rainfall events percolating along fractures of the ignimbritic layers and voids of the loose deposits. The depleted levels of deuterium and δ18O may explain the amount effect on isotopic fractionation. The rather high tritium counts and moderately low salinity may further imply recent recharge and relatively faster transport by both focused and diffused mechanisms at the respective

  4. [Bioactive dressings].

    PubMed

    Grasset, N; Raffoul, W; Bigliardi, P

    2010-02-17

    Wound healing is a complex process involving several cell types (keratinocytes, fibroblasts, endothelial cells, etc.) as well as many growth factors (PDGF, TGF-betas, FGFs, VEGF, etc.). It can be challenging when wounds are deep or very large (third degree burn, ulceration after cutaneous tumor resection) or in presence of peripheral vascular disease, metabolic disturbances or peripheral neuropathy (chronic vascular or diabetic wounds). In order to promote skin regeneration, numerous bioactive dressings combining cells, matrices and growth factors are available on the market. This article provides a general overview of the various product categories and presents their main indications. The principal axes of the biomedical research in this area are also discussed.

  5. Dressings for chronic wounds.

    PubMed

    Powers, Jennifer Gloeckner; Morton, Laurel M; Phillips, Tania J

    2013-01-01

    Covering wounds, acute and chronic, is one of the most fundamental activities of any medical practitioner. Although wound dressings primarily serve to contain the "good" and keep out the "bad," research has characterized more specifically the sophisticated interaction between the human wound bed and its dressing counterpart. Wound dressings for today's chronic wounds come in many flavors, ranging from the classic types of moisture-retentive dressings to silver-coated varieties to biologic dressings serving as skin substitutes. Moisture-retentive dressing types include foams, films, hydrogels, hydrocolloids, and alginates. Appropriate use of these dressings can help to keep the wound bed moist, which allows for epithelial migration, angiogenesis, retention of growth factors, autolytic debridement, and maintenance of electrical gradients. PMID:23742280

  6. Dress Codes and Uniforms.

    ERIC Educational Resources Information Center

    Lumsden, Linda; Miller, Gabriel

    2002-01-01

    Students do not always make choices that adults agree with in their choice of school dress. Dress-code issues are explored in this Research Roundup, and guidance is offered to principals seeking to maintain a positive school climate. In "Do School Uniforms Fit?" Kerry White discusses arguments for and against school uniforms and summarizes the…

  7. [Healing "booster" dressings].

    PubMed

    Fromantin, Isabelle; Téot, Luc; Meaume, Sylvie

    2011-09-01

    The relationship between the dressing and the wound is vital to clinical effectiveness. The more-or-less standard wound-surface coverings have been replaced with initial dressings, referred to as modern dressings, which contain an oily and sticky compound. They provide a moist medium by applying the basic mechanistic principles (liquid absorption and release). Other types of products and techniques modify the behaviour of wound cells by acting directly through irritation, biochemical stimulation or genetic modification of the cells, which accelerates the healing process.

  8. Dresses Make the Girl: Gender and Identity from "The Hundred Dresses" to "10,000 Dresses"

    ERIC Educational Resources Information Center

    Smulders, Sharon

    2015-01-01

    This paper offers a close reading of two works, Eleanor Estes' "The Hundred Dresses" (1944) and Marcus Ewert's "10,000 Dresses" (2008), that feature in current anti-bullying campaigns. Starting with "The Hundred Dresses," this essay examines how Estes' use of the school story not only exposes the social dynamics of…

  9. Wound Healing and the Dressing*

    PubMed Central

    Scales, John T.

    1963-01-01

    The evolution of surgical dressings is traced from 1600 b.c. to a.d. 1944. The availability of an increasing variety of man-made fibres and films from 1944 onwards has stimulated work on wound dressings, and some of the more important contributions, both clinical and experimental, are discussed. The functions of a wound dressing and the properties which the ideal wound dressing should possess are given. The necessity for both histological and clinical evaluation of wound dressings in animals and in man is stressed. Wound dressings are the most commonly used therapeutic agents, but there is no means whereby their performance can be assessed. An attempt should be made either nationally or internationally to establish a standard method of assessing the performance of wound dressings. For this it is necessary to have an internationally agreed standard dressing which could be used as a reference or control dressing in all animal and human work. The only animal with skin morphologically similar to that of man is the domestic pig. Three types of wounds could be used: (1) partial-thickness wounds; (2) full-thickness excisions; and (3) third-degree burns. The development of standard techniques for the assessment of the efficiency of wound dressings would be of considerable benefit to the research worker, the medical profession, the patient, and the surgical dressings industry. PMID:13976490

  10. Periodontal Dressing: A Review Article

    PubMed Central

    Baghani, Zahra; Kadkhodazadeh, Mahdi

    2013-01-01

    The purpose of this paper was to review the commercially available periodontal dressings, their physical and chemical properties, biocompatibility and therapeutic effects. Electronic search of scientific papers from 1956 to 2012 was carried out using PubMed, Scopus and Wiley InterScience search engines using the searched terms periodontal dressing, periodontal pack. Numerous in vitro and in vivo studies have evaluated various properties of periodontal dressings. Physical and chemical properties of dressings are directly related to their dimensional changes and adhesion properties. Their biocompatibility and therapeutic effect are among the other factors evaluated in the literature. Chlorhexidine is the most commonly used antibacterial agent in studies. In general, when comparing the advantages with the disadvantages, application of periodontal dressing seems to be beneficial. Numerous factors are involved in selection of an optimal dressing such as surgeon’s intention, required time for the dressing to remain on the surgery site and its dimensional changes. PMID:24578815

  11. DRESS syndrome in ophthalmic patients.

    PubMed

    Sousa, Jacqueline Martins de; Nascimento, Heloisa; Belfort, Rubens

    2016-01-01

    Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially fatal adverse drug reaction associated with skin rash, fever, eosinophilia, and multiple organ injury. A number of pharmacological agents are known to cause DRESS syndrome such as allopurinol, anticonvulsants, vancomycin, trimethoprime-sulfamethoxazole, and pyrimethamine-sulfadiazine. Here, we describe two patients who developed DRESS syndrome during ocular treatment. The first case was being treated for late postoperative endophthalmitis with topical antibiotics, intravenous cephalothin, meropenem, and intravitreal injection of vancomycin and ceftazidime before symptoms developed. We were unable to identify the causal drug owing to the large number of medications concurrently administered. The second case presented with DRESS syndrome symptoms during ocular toxoplasmosis treatment. In this case, a clearer association with pyrimethamine-sulfadiazine was observed. As a result of the regular prescription of pharmacological agents associated with DRESS syndrome, ophthalmologists should be aware of the potentially serious complications of DRESS syndrome. PMID:27463633

  12. [DRESS syndrome to sulfasalzine].

    PubMed

    Bourguignon, R; Piérrard-Franchimont, C; Paquet, P; Piérard, G E

    2006-09-01

    We report a case of drug hypersensibility syndrome (DRESS syndrome) developed one month after initiation of a treatment by sulfasalazine. Due to the severity of the cytolytic hepatic damages as observed in this case, we emphasize the importance of suggesting this diagnosis in any patient developing a cutaneous rash and an alteration of the general health status after initiation of a new treatment. The hematologic alterations which represent a key feature for the diagnosis may rash. develop only a few days after the cutaneous rash. PMID:17112165

  13. [Modern dressings. Hydrogels].

    PubMed

    Sedlarik, K M; Vacik, J; Wichterle, O; Hájek, M

    1995-02-01

    Hydrogels are occlusive types of dressings. They are three-dimensional nets made up of hydrophil polymers. They can be produced from synthetic or semisynthetic materials or a combination of the two. Hydrogels retain different percentages of water but are themselves insoluble in water. This is why they maintain on the wound surface their structure and do not dissolve. They are suited for the dressing of wounds with low secretion such as grade I and II burns, grade I and II bedsores and above all epithelial defects, major skin abrasions and areas after collection of epithelial grafts. Their use is contraindicated in infected wounds, in wounds with a massive secretion and ulcers of arterial origin. Although the domain of their clinical use are clean granulating or already epithelizing wounds, they are very well suited also for rehydration of dry and black skin necroses. Their advantages include minimal pain in the wound as well as the fact that they can be left on the wound without redressing till complete healing. This is made possible also by the fact that they are translucent. PMID:7777948

  14. 21 CFR 878.4022 - Hydrogel wound dressing and burn dressing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hydrogel wound dressing and burn dressing. 878.4022 Section 878.4022 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Hydrogel wound dressing and burn dressing. (a) Identification. A hydrogel wound dressing is a sterile...

  15. Black Hole Caught Zapping Galaxy into Existence?

    NASA Astrophysics Data System (ADS)

    2009-11-01

    across the whole electromagnetic spectrum; particularly spectacular is the case of quasars, where the active core is so overwhelmingly bright that it outshines the luminosity of the host galaxy. [2] This part of the study is based on observations performed at mid-infrared wavelengths, with the powerful VLT spectrometer and imager for the mid-infrared (VISIR) instrument at the VLT, combined with additional data including: spectra acquired using VLT-FORS, optical and infrared images from the NASA/ESA Hubble Space Telescope, and radio observations from the Australia Telescope National Facility. [3] Most galaxies in the local Universe contain a supermassive black hole with a mass about 1/700th the mass of the stellar bulge. The origin of this black hole mass versus stellar mass relation is one of the most debated subjects in modern astrophysics. More information This research was presented in papers published in the journal Astronomy & Astrophysics: "Quasar induced galaxy formation: a new paradigm?" by Elbaz et al., and in the Astrophysical Journal "The QSO HE0450-2958: Scantily dressed or heavily robed? A normal quasar as part of an unusual ULIRG" by Jahnke et al. The team is composed of David Elbaz (Service d'Astrophysique, CEA Saclay, France), Knud Jahnke (Max Planck Institute for Astronomy, Heidelberg, Germany), Eric Pantin (Service d'Astrophysique, CEA Saclay, France), Damien Le Borgne (Paris University 6 and CNRS, Institut d'Astrophysique de Paris, France) and Géraldine Letawe (Institut d'Astrophysique et de Géophysique, Université de Liège, Belgium). ESO, the European Southern Observatory, is the foremost intergovernmental astronomy organisation in Europe and the world's most productive astronomical observatory. It is supported by 14 countries: Austria, Belgium, the Czech Republic, Denmark, France, Finland, Germany, Italy, the Netherlands, Portugal, Spain, Sweden, Switzerland and the United Kingdom. ESO carries out an ambitious programme focused on the design

  16. DRESS Syndrome Presents as Leukoencephalopathy.

    PubMed

    Tonekaboni, Seyed Hasan; Jafari, Narjes; Chavoshzadeh, Zahra; Shamsian, Bibi Shahin; Rezaei, Nima

    2015-01-01

    DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is a potentially life-threatening syndrome, which reflects a serious hypersensitivity reaction to drugs, presenting by generalized skin rash, fever, eosinophilia, atypical lymphocytosis, and internal organ involvement. Herein a 21-month old male infant with DRESS and Encephalopathy syndrome is presented who complicated after phenobarbital usage that persisted due to phenytoin cream usage. The case received phenobarbital after a seizure disorder presented as "status epilepticus". He developed drug eruption, fever, hepatosplenomegaly, increased liver enzymes, encephalopathy and progressive loss of consciousness with extensive hyperintense white matter lesions in brain MRI. After discontinuation of phenobarbital and phenytoin, all symptoms were resolved, while brain MRI became normal after two months. To our best knowledge, this is the first reported case that developed leukoencephalopathy along with DRESS syndrome. PMID:27411428

  17. Sushi hand roll dressing for thumb polydactyly.

    PubMed

    Yen, Chi-Hung; Ho, Pak-Cheong; Hung, Leung-Kim

    2012-06-12

    Surgery for thumb polydactyly is a commonly performed orthopaedic procedure in Asia Pacific region. Despite extensive publications on topical dressing methods and dressing materials in paediatric wounds, there is no single design that affords a secure and yet comfortable post-operative wound dressing for thumb polydactyly. We have devised a new dressing method, which can easily be fabricated for such purpose from readily available materials in operation theatre.

  18. Fournier's Gangrene: Conventional Dressings versus Dressings with Dakin's Solution

    PubMed Central

    Altunoluk, Bülent; Resim, Sefa; Efe, Erkan; Eren, Mustafa; Benlioglu, Can; Kankilic, Nazim; Baykan, Halit

    2012-01-01

    Purpose. Fournier's gangrene is a fulminant and destructive inflammation of the scrotum, penis, and perineum. The objective of this study was to compare 2 different approaches to wound management after aggressive surgical debridement. Methods. Data from 14 patients with Fournier's gangrene were retrospectively collected (2005–2011). Once the patients were stabilized following surgery, they were treated with either daily antiseptic (povidone iodine) dressings (group I, n = 6) or dressings with dakin's solution (sodium hypochloride) (group II, n = 8). Results. The mean age of the patients was 68.2 ± 7.8 (55–75) years in group I and 66.9 ± 10.2 (51–79) years in group II. Length of hospital stay was 13 ± 3.5 (7–16) days in group I and 8.9 ± 3.0 (4–12) days in group II (P < 0.05). The number and rate of mortality was 1/6 (16.7%) in group I, and 1/8 (12.5%) in group II. Conclusions. The hospitalization time can be reduced with the use of dakin's solution for the dressings in the treatment of FG. Also, dressings with dakin's solution seems to have favorable effects on morbidity and mortality. Consequently dakin's solution may alter the treatment of this disastrous disease by reducing cost, morbidity and mortality. PMID:22567424

  19. School Dress Codes and Uniform Policies.

    ERIC Educational Resources Information Center

    Anderson, Wendell

    2002-01-01

    Opinions abound on what students should wear to class. Some see student dress as a safety issue; others see it as a student-rights issue. The issue of dress codes and uniform policies has been tackled in the classroom, the boardroom, and the courtroom. This Policy Report examines the whole fabric of the debate on dress codes and uniform policies…

  20. Redressing Cross-Dressed Shakespeare

    ERIC Educational Resources Information Center

    Martin, Thomas L.; Pesta, Duke

    2003-01-01

    Gender critics obsess over the boy actors who played female roles on the Elizabethan stage. But, in their far-fetched interpretation of Shakespearean drama as a spectacle of cross dressing, these new historicists lose sight of a fundamental principle of theater. Thomas Martin and Duke Pesta argue that with their prurient chatter of "the…

  1. Wound Management: The Occlusive Dressing

    PubMed Central

    Rheinecker, Scot B.

    1995-01-01

    Superficial wounds resulting from athletic injury are common in sports medicine. Although such wounds can be quite painful, they are usually merely inconvenient to the athlete. If improperly managed, however, superficial wounds may heal slowly and cause unnecessary scar tissue proliferation at the wound site. Scar formation causes the wound to break open frequently and puts the athlete at risk of cross-contamination by pathogenic organisms. New advances in the science of wound management strongly favor the use of occlusive dressings to increase patient comfort, increase patient compliance, decrease the risk of infection, and decrease overall healing time. Occlusion has clearly been proven to aid in the healing of superficial wounds and should be considered as a treatment alternative for wounds in the sports medicine setting. In this paper, I discuss three of the most widely used types of occlusive dressings: 1) films, 2) hydrogels, and 3) hydrocolloids. PMID:16558325

  2. Wound dressings. Past, present, and future.

    PubMed

    Horncastle, J

    1995-01-01

    The discovery that "moist" dressings can promote faster healing has led to a number of innovations in wound care. Modern dressings are playing an active part in the healing process and, in the future, will be condition-specific rather than offering off-the-shelf solutions. Focusing on hydrocolloids and alginates, which are used in bioactive dressings, this article reviews the developments that have been made to date, and includes discussion of the demands being made on the manufacturing process.

  3. Dressed spin of {sup 3}He

    SciTech Connect

    Esler, A.; Peng, J. C.; Chandler, D.; Howell, D.; Lamoreaux, S. K.; Liu, C. Y.; Torgerson, J. R.

    2007-11-15

    We report a measurement of dressed spin effects of polarized {sup 3}He atoms from a cold atomic source traversing a region of a constant magnetic field B{sub 0} and a transverse oscillatory dressing field B{sub d}cos{omega}{sub d}t. The observed effects are compared with a numerical simulation using the Bloch equation as well as a calculation based on the dressed atom formalism. An application of the dressed spin of {sup 3}He for a proposed neutron electric dipole moment measurement is also discussed.

  4. Fluid handling properties of hydrogel dressings.

    PubMed

    Thomas, S; Hay, P

    1995-04-01

    The fluid handling properties of four hydrogel dressings were examined in a laboratory-based study to determine their ability to absorb liquid from or donate liquid to a range of standard test substrates simulating wound tissue in various states of hydration. The tests suggest that three of the dressings are likely to be effective fluid-donating agents, and one of the dressings has a dual ability to donate or absorb liquid depending upon moisture content and nature of the substrate to which it is applied. These observations are discussed in the context of the clinical use of hydrogel dressings.

  5. Dressed qubits in nuclear spin baths

    SciTech Connect

    Wu Lianao

    2010-04-15

    We present a method to encode a dressed qubit into the product state of an electron spin localized in a quantum dot and its surrounding nuclear spins via a dressing transformation. In this scheme, the hyperfine coupling and a portion of a nuclear dipole-dipole interaction become logic gates, while they are the sources of decoherence in electron-spin qubit proposals. We discuss errors and corrections for the dressed qubits. Interestingly, the effective Hamiltonian of nuclear spins is equivalent to a pairing Hamiltonian, which provides the microscopic mechanism to protect dressed qubits against decoherence.

  6. [Negative pressure wound therapy dressings].

    PubMed

    Téot, Luc

    2016-01-01

    There are many different forms of negative pressure wound therapy dressings and it is important to distinguish clearly between each type. They enable the treatment to be adapted to the shape and depth of the wound, its degree of exudation and the persistence of the fibrinous areas on the surface. The machine's traction capacity, measured in mm of mercury (Hg), must be controlled to establish the healing profile: the more powerful the machine and the more contact there is between the foam and the wound, the faster the formation of the granulation tissue. There are many different solutions which are implemented in accordance with the clinical assessment of the wound.

  7. Acemannan hydrogel dressing versus saline dressing for pressure ulcers. A randomized, controlled trial.

    PubMed

    Thomas, D R; Goode, P S; LaMaster, K; Tennyson, T

    1998-10-01

    Aloe vera has been used for centuries as a topical treatment for various conditions and as a cathartic. An amorphous hydrogel dressing derived from the aloe plant (Carrasyn Gel Wound Dressing, Carrington Laboratories, Inc., Irving, TX) is approved by the Food and Drug Administration for the management of Stages I through IV pressure ulcers. To evaluate effectiveness of this treatment, 30 patients were randomized to receive either daily topical application of the hydrogel study dressing (acemannan hydrogel wound dressing) or a moist saline gauze dressing. Complete healing of the study ulcer occurred in 19 of 30 subjects (63%) during the 10-week observation period. No difference was observed in complete healing between the experimental and the control groups (odds ratio 0.93, 95% CI 0.16, 5.2). This study indicates that the acemannan hydrogel dressing is as effective as, but is not superior to, a moist saline gauze wound dressing for the management of pressure ulcers.

  8. Role Conflict and Conformity in Dress.

    ERIC Educational Resources Information Center

    Jasper, Cynthia R.; Roach-Higgins, Mary Ellen

    1988-01-01

    Examined conflict regarding what form of dress is appropriate for Roman Catholic priest. Data from 5,475 American Catholic priests revealed that priests who conformed to church regulations regarding dress differed from nonconformists in beliefs about their roles as priests and in their opinions of church reform, commitment to the priesthood,…

  9. The many colours of 'the dress'.

    PubMed

    Gegenfurtner, Karl R; Bloj, Marina; Toscani, Matteo

    2015-06-29

    There has been an intense discussion among the public about the colour of a dress, shown in a picture posted originally on Tumblr (http://swiked.tumblr.com/post/112073818575/guys-please-help-me-is-this-dress-white-and; accessed on 10:56 am GMT on Tue 24 Mar 2015). Some people argue that they see a white dress with golden lace, while others describe the dress as blue with black lace. Here we show that the question "what colour is the dress?" has more than two answers. In fact, there is a continuum of colour percepts across different observers. We measured colour matches on a calibrated screen for two groups of observers who had reported different percepts of the dress. Surprisingly, differences between the two groups arose mainly from differences in lightness, rather than chromaticity of the colours they adjusted to match the dress. We speculate that the ambiguity arises in the case of this particular image because the distribution of colours within the dress closely matches the distribution of natural daylights. This makes it more difficult to disambiguate illumination changes from those in reflectance. PMID:25981790

  10. Honey: A Biologic Wound Dressing.

    PubMed

    Molan, Peter; Rhodes, Tanya

    2015-06-01

    Honey has been used as a wound dressing for thousands of years, but only in more recent times has a scientific explanation become available for its effectiveness. It is now realized that honey is a biologic wound dressing with multiple bioactivities that work in concert to expedite the healing process. The physical properties of honey also expedite the healing process: its acidity increases the release of oxygen from hemoglobin thereby making the wound environment less favorable for the activity of destructive proteases, and the high osmolarity of honey draws fluid out of the wound bed to create an outflow of lymph as occurs with negative pressure wound therapy. Honey has a broad-spectrum antibacterial activity, but there is much variation in potency between different honeys. There are 2 types of antibacterial activity. In most honeys the activity is due to hydrogen peroxide, but much of this is inactivated by the enzyme catalase that is present in blood, serum, and wound tissues. In manuka honey, the activity is due to methylglyoxal which is not inactivated. The manuka honey used in wound-care products can withstand dilution with substantial amounts of wound exudate and still maintain enough activity to inhibit the growth of bacteria. There is good evidence for honey also having bioactivities that stimulate the immune response (thus promoting the growth of tissues for wound repair), suppress inflammation, and bring about rapid autolytic debridement. There is clinical evidence for these actions, and research is providing scientific explanations for them. PMID:26061489

  11. Honey: A Biologic Wound Dressing.

    PubMed

    Molan, Peter; Rhodes, Tanya

    2015-06-01

    Honey has been used as a wound dressing for thousands of years, but only in more recent times has a scientific explanation become available for its effectiveness. It is now realized that honey is a biologic wound dressing with multiple bioactivities that work in concert to expedite the healing process. The physical properties of honey also expedite the healing process: its acidity increases the release of oxygen from hemoglobin thereby making the wound environment less favorable for the activity of destructive proteases, and the high osmolarity of honey draws fluid out of the wound bed to create an outflow of lymph as occurs with negative pressure wound therapy. Honey has a broad-spectrum antibacterial activity, but there is much variation in potency between different honeys. There are 2 types of antibacterial activity. In most honeys the activity is due to hydrogen peroxide, but much of this is inactivated by the enzyme catalase that is present in blood, serum, and wound tissues. In manuka honey, the activity is due to methylglyoxal which is not inactivated. The manuka honey used in wound-care products can withstand dilution with substantial amounts of wound exudate and still maintain enough activity to inhibit the growth of bacteria. There is good evidence for honey also having bioactivities that stimulate the immune response (thus promoting the growth of tissues for wound repair), suppress inflammation, and bring about rapid autolytic debridement. There is clinical evidence for these actions, and research is providing scientific explanations for them.

  12. Alginate dressing as a donor site haemostat.

    PubMed Central

    Groves, A. R.; Lawrence, J. C.

    1986-01-01

    An alginate fibre dressing has been used to reduce blood loss from skin graft donor sites. Significant haemostasis has been achieved in the immediate post surgery phase and no adverse reactions observed. Images Fig. 1 PMID:3511833

  13. Colour Vision: Understanding #TheDress.

    PubMed

    Brainard, David H; Hurlbert, Anya C

    2015-06-29

    A widely-viewed image of a dress elicits striking individual variation in colour perception. Experiments with multiple variants of the image suggest that the individual differences may arise through the action of visual mechanisms that normally stabilise object colour.

  14. A dressed spin qubit in silicon

    DOE PAGES

    Laucht, Arne; Kalra, Rachpon; Simmons, Stephanie; Dehollain, Juan P.; Muhonen, Juha T.; Mohiyaddin, Fahd A.; Freer, Solomon; Hudson, Fay E.; Itoh, Kohei M.; Jamieson, David N.; et al

    2016-10-17

    Coherent dressing of a quantum two-level system provides access to a new quantum system with improved properties—a different and easily tunable level splitting, faster control and longer coherence times. In our work we investigate the properties of the dressed, donor-bound electron spin in silicon, and assess its potential as a quantum bit in scalable architectures. The two dressed spin-polariton levels constitute a quantum bit that can be coherently driven with an oscillating magnetic field, an oscillating electric field, frequency modulation of the driving field or a simple detuning pulse. We measure coherence times of T*2p = 2.4 ms and THahn2pmore » = 9 ms, one order of magnitude longer than those of the undressed spin. Moreover, the use of the dressed states enables coherent coupling of the solid-state spins to electric fields and mechanical oscillations.« less

  15. [Hydrocellular dressings, 25 years of evolution].

    PubMed

    Lurton, Yves

    2016-01-01

    Hydrocellular dressings have evolved considerably over the last 25 years. Manufacturers have worked to increase their absorbency, to make them easier for caregivers to use and to improve their comfort for the patients. This class now comprises a diverse range of dressings. Their inclusion on the list of products and services approved for reimbursement, given the low level of evidence provided by the clinical studies currently available, depends on their technical characteristics assessed in vitro. PMID:26763563

  16. 21 CFR 878.4022 - Hydrogel wound dressing and burn dressing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Hydrogel wound dressing and burn dressing. 878.4022 Section 878.4022 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices §...

  17. 21 CFR 878.4022 - Hydrogel wound dressing and burn dressing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Hydrogel wound dressing and burn dressing. 878.4022 Section 878.4022 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices §...

  18. 21 CFR 878.4022 - Hydrogel wound dressing and burn dressing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Hydrogel wound dressing and burn dressing. 878.4022 Section 878.4022 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices §...

  19. 21 CFR 878.4022 - Hydrogel wound dressing and burn dressing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Hydrogel wound dressing and burn dressing. 878.4022 Section 878.4022 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices §...

  20. Choosing a Wound Dressing Based on Common Wound Characteristics

    PubMed Central

    Dabiri, Ganary; Damstetter, Elizabeth; Phillips, Tania

    2016-01-01

    Significance: Chronic wounds are a major healthcare burden.The practitioner should have an appropriate understanding of both the etiology of the wound as well as the optimal type of dressings to use. Fundamental wound characteristics may be used to guide the practitioner's choice of dressings. The identification of optimal dressings to use for a particular wound type is an important element in facilitating wound healing. Recent Advances: Researchers have sought to design wound dressings that aim to optimize each stage in the healing process. In addition, dressings have been designed to target and kill infection-causing bacteria, with the incorporation of antimicrobial agents. Critical Issues: Chronic wounds are frequently dynamic in presentation, and the numerous wound dressings available make dressing selection challenging for the practitioner. Choosing the correct dressing decreases time to healing, provides cost-effective care, and improves patient quality of life. Future Directions: Research into the mechanisms of wound healing has enhanced our ability to heal chronic wounds at a faster rate through the use of moisture-retentive dressings. Newer dressings are incorporating the use of nanotechnology by incorporating miniature electrical sensors into the dressing. These dressings are engineered to detect changes in a wound environment and alert the patient or practitioner by altering the color of the dressing or sending a message to a smartphone. Additional investigations are underway that incorporate biologic material such as stem cells into dressings. PMID:26858913

  1. Ovine-Based Collagen Matrix Dressing: Next-Generation Collagen Dressing for Wound Care

    PubMed Central

    Bohn, Gregory; Liden, Brock; Schultz, Gregory; Yang, Qingping; Gibson, Daniel J.

    2016-01-01

    Significance: Broad-spectrum metalloproteinase (MMP) reduction along with inherent aspects of an extracellular matrix (ECM) dressing can bring about improved wound healing outcomes and shorter treatment duration. Initial reports of clinical effectiveness of a new ovine-based collagen extracellular matrix (CECM) dressing demonstrate benefits in chronic wound healing. Recent Advances: CECM dressings are processed differently than oxidized regenerated cellulose/collagen dressings. CECM dressings consist primarily of collagens I and III arranged as native fibers that retain the three-dimensional architecture present in tissue ECM. As such, ovine-based ECM dressings represent a new generation of collagen dressings capable of impacting a broad spectrum of MMP excess known to be present in chronic wounds. Critical Issues: While MMPs are essential in normal healing, elevated presence of MMPs has been linked to wound failure. Collagen has been shown to reduce levels of MMPs, acting as a sacrificial substrate for excessive proteases in a chronic wound. Preserving collagen dressings in a more native state enhances bioactivity in terms of the ability to affect the chronic wound environment. Clinical observation and assessment may not be sufficient to identify a wound with elevated protease activity that can break down ECM, affect wound fibroblasts, and impair growth factor response. Future Directions: Collagen dressings that target broad-spectrum excessive MMP levels and can be applied early in the course of care may positively impact healing rates in difficult wounds. Next-generation collagen dressings offer broader MMP reduction capacity while providing a provisional dermal matrix or ECM. PMID:26858910

  2. Control of photodetachment spectra through laser dressing

    NASA Astrophysics Data System (ADS)

    Morrison, Nathan; Greene, Chris

    2013-05-01

    Photodetachment and photoionization spectra often display rich resonance structures. The properties of these spectra can be modified through dressing with intense laser fields, providing control over photon absorption and the emitted electron. We present a Floquet R-matrix method for calculating photodetachment cross sections in the presence of a dressing laser. The full wave functions in the Floquet formalism for bound and escaping electrons are found by solving the Schrödinger equation near the atomic core and applying analytic boundary conditions outside of the interaction region. These calculations are used to investigate the modification of existing resonances, such as modifying the shape, or q parameter, of Feshbach resonances. We also investigate the creation of new resonances in cases where high-lying bound states become autoionizing through the absorption of dressing laser photons. This work was supported by the DOE.

  3. Wound Dressings and Comparative Effectiveness Data

    PubMed Central

    Sood, Aditya; Granick, Mark S.; Tomaselli, Nancy L.

    2014-01-01

    Significance: Injury to the skin provides a unique challenge, as wound healing is a complex and intricate process. Acute wounds have the potential to move from the acute wound to chronic wounds, requiring the physician to have a thorough understanding of outside interventions to bring these wounds back into the healing cascade. Recent Advances: The development of new and effective interventions in wound care remains an area of intense research. Negative pressure wound therapy has undoubtedly changed wound care from this point forward and has proven beneficial for a variety of wounds. Hydroconductive dressings are another category that is emerging with studies underway. Other modalities such as hyperbaric oxygen, growth factors, biologic dressings, skin substitutes, and regenerative materials have also proven efficacious in advancing the wound-healing process through a variety of mechanisms. Critical Issues: There is an overwhelming amount of wound dressings available in the market. This implies the lack of full understanding of wound care and management. The point of using advanced dressings is to improve upon specific wound characteristics to bring it as close to “ideal” as possible. It is only after properly assessing the wound characteristics and obtaining knowledge about available products that the “ideal” dressing may be chosen. Future Directions: The future of wound healing at this point remains unknown. Few high-quality, randomized controlled trials evaluating wound dressings exist and do not clearly demonstrate superiority of many materials or categories. Comparative effectiveness research can be used as a tool to evaluate topical therapy for wound care moving into the future. Until further data emerge, education on the available products and logical clinical thought must prevail. PMID:25126472

  4. Tiny patients, tiny dressings: a guide to the neonatal PICC dressing change.

    PubMed

    Sharpe, Elizabeth L

    2008-06-01

    Advances in neonatology now support the survival of the tiniest of infants. The peripherally inserted central catheter (PICC) has now become an integral part of routine practice in neonatal intensive care units around the world. Keen attention to safe maintenance of these devices is essential. A properly applied and maintained PICC dressing is the first line of defense to minimize the risk of complications such as dislodgement, migration, and infection. This article describes a neonatal PICC dressing change and discusses the frequently encountered quandaries surrounding this important procedure, including dressing materials, frequency, site preparation, barrier precautions, and other relevant concerns.

  5. Occlusive Dressings and the Healing of Standardized Abrasions

    PubMed Central

    Beam, Joel W

    2008-01-01

    Context: Acute skin trauma during sport participation, resulting in partial-thickness abrasions, is common. The limited investigations focusing on the acute wound environment and dressing techniques and the subsequent lack of evidence-based standards complicate clinical wound care decisions. Objective: To examine the effects of occlusive dressings on healing of standardized, partial-thickness abrasions. Design: Controlled, counterbalanced, repeated-measures design. Setting: University laboratory. Patients or Other Participants: Sixteen healthy women (n  =  10) and men (n  =  6). Intervention(s): Four standardized, partial-thickness abrasions were inflicted. Film, hydrogel, and hydrocolloid occlusive dressings and no dressing (control) were applied. Participants returned on postwound days 1, 3, 5, 7, 10, and 14 for digital imaging. Wound healing time was measured by change in wound contraction (cm2) and change in wound color (chromatic red) and luminance in red, green, and blue color values. Main Outcome Measure(s): Wound contraction, color (chromatic red), and luminance. Results: A day-by-dressing interaction was found for wound contraction, color, and luminance. Post hoc testing indicated that the film and hydrocolloid dressings produced greater wound contraction than the hydrogel and no dressing on days 7 and 10. Film, hydrogel, and hydrocolloid dressings also resulted in greater wound contraction than the control on day 14. Hydrocolloid dressings produced smaller measures of color and greater measures of luminance than no dressing on day 7. Film, hydrogel, and hydrocolloid dressings also resulted in smaller measures of color and greater measures of luminance compared with no dressing on days 10 and 14. Conclusions: When compared with the control (no dressing), the film, hydrogel, and hydrocolloid occlusive dressings were associated with a faster healing rate of partial-thickness abrasions across time measured by wound contraction, color, and luminance

  6. Dressing of Cognitively Impaired Nursing Home Residents: Description and Analysis

    ERIC Educational Resources Information Center

    Cohen-Mansfield, Jiska; Creedon, Michael A.; Malone, Thomas; Parpura-Gill, Aleksandra; Dakheel-Ali, Maha; Heasly, Christopher

    2006-01-01

    Purpose: Getting dressed is an activity that is of particular difficulty for many persons with dementia, given the need for hand-eye coordination, fine motor skills, and overall planning skills. Despite several studies concerning interventions to improve dressing behavior, very little is known about the dressing process as it is currently…

  7. Collagen Dressing Versus Conventional Dressings in Burn and Chronic Wounds: A Retrospective Study

    PubMed Central

    Singh, Onkar; Gupta, Shilpi Singh; Soni, Mohan; Moses, Sonia; Shukla, Sumit; Mathur, Raj Kumar

    2011-01-01

    Objective: Biological dressings like collagen are impermeable to bacteria, and create the most physiological interface between the wound surface and the environment. Collagen dressings have other advantages over conventional dressings in terms of ease of application and being natural, non-immunogenic, non-pyrogenic, hypo-allergenic, and pain-free. This study aims to compare the efficacy of collagen dressing in treating burn and chronic wounds with that of conventional dressing materials. Materials and Methods: The records of 120 patients with chronic wounds of varied aetiologies and with mean age 43.7 years were collected and analyzed. The patients had been treated either with collagen or other conventional dressing materials including silver sulfadiazine, nadifloxacin, povidone iodine, or honey (traditional dressing material). Patients with co-morbidities that could grossly affect the wound healing like uncontrolled diabetes mellitus, chronic liver or renal disease, or major nutritional deprivation were not included. For the purpose of comparison the patients were divided into two groups; ‘Collagen group’ and ‘Conventional group’, each having 60 patients. For assessment the wound characteristics (size, edge, floor, slough, granulation tissue, and wound swab or pus culture sensitivity results) were recorded. With start of treatment, appearance of granulation tissue, completeness of healing, need for skin grafting, and patients’ satisfaction was noted for each patient in both groups. Results: With two weeks of treatment, 60% of the ‘collagen group’ wounds and only 42% of the ‘conventional group’ wounds were sterile (P=0.03). Healthy granulation tissue appeared earlier over collagen-dressed wounds than over conventionally treated wounds (P=0.03). After eight weeks, 52 (87%) of ‘collagen group’ wounds and 48 (80%) of ‘conventional group’ wounds were >75% healed (P=0.21). Eight patients in the ‘collagen group’ and 12 in the

  8. "Posh Music Should Equal Posh Dress": An Investigation into the Concert Dress and Physical Appearance of Female Soloists

    ERIC Educational Resources Information Center

    Griffiths, Noola K.

    2010-01-01

    This study investigates the effects of concert dress and physical appearance on perceptions of female classical soloists' musical abilities over a range of genres. Four female violinists were recorded playing three pieces, in four styles of dress of varying formality. Each combination of performer, piece and dress was recorded twice, once as the…

  9. Surgical instruments and dressings: an information service.

    PubMed Central

    Lakie, M H; McElroy, A R

    1975-01-01

    A regional information service on surgical equipment, instruments, and dressings is proposed that would be staffed by information scientists. It would appreciably reduce the time spent on administration and make the buying of equipment more efficient. Such a service could be extended to all health service staff. PMID:1192114

  10. Gribov's horizon and the ghost dressing function

    SciTech Connect

    Boucaud, Ph.; Leroy, J. P.; Le Yaouanc, A.; Micheli, J.; Pene, O.; Rodriguez-Quintero, J.

    2009-11-01

    We study a relation recently derived by K. Kondo at zero momentum between the Zwanziger's horizon function, the ghost dressing function and Kugo's functions u and w. We agree with this result as far as bare quantities are considered. However, assuming the validity of the horizon gap equation, we argue that the solution w(0)=0 is not acceptable since it would lead to a vanishing renormalized ghost dressing function. On the contrary, when the cutoff goes to infinity, u(0){yields}{infinity}, w(0){yields}-{infinity} such that u(0)+w(0){yields}-1. Furthermore w and u are not multiplicatively renormalizable. Relaxing the gap equation allows w(0)=0 with u(0){yields}-1. In both cases the bare ghost dressing function, F(0,{lambda}), goes logarithmically to infinity at infinite cutoff. We show that, although the lattice results provide bare results not so different from the F(0,{lambda})=3 solution, this is an accident due to the fact that the lattice cutoffs lie in the range 1-3 GeV{sup -1}. We show that the renormalized ghost dressing function should be finite and nonzero at zero momentum and can be reliably estimated on the lattice up to powers of the lattice spacing; from published data on a 80{sup 4} lattice at {beta}=5.7 we obtain F{sub R}(0,{mu}=1.5 GeV){approx_equal}2.2.

  11. 21 CFR 169.115 - French dressing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... emulsified viscous fluid food prepared from vegetable oil(s) and one or both of the acidifying ingredients... this section may also be used. The vegetable oil(s) used may contain an optional crystallization... vegetable oil. French dressing may be mixed and packed in an atmosphere in which air is replaced in whole...

  12. 21 CFR 169.115 - French dressing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... emulsified viscous fluid food prepared from vegetable oil(s) and one or both of the acidifying ingredients... this section may also be used. The vegetable oil(s) used may contain an optional crystallization... vegetable oil. French dressing may be mixed and packed in an atmosphere in which air is replaced in whole...

  13. 21 CFR 169.115 - French dressing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... emulsified viscous fluid food prepared from vegetable oil(s) and one or both of the acidifying ingredients... this section may also be used. The vegetable oil(s) used may contain an optional crystallization... vegetable oil. French dressing may be mixed and packed in an atmosphere in which air is replaced in whole...

  14. 21 CFR 169.115 - French dressing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... emulsified viscous fluid food prepared from vegetable oil(s) and one or both of the acidifying ingredients... this section may also be used. The vegetable oil(s) used may contain an optional crystallization... vegetable oil. French dressing may be mixed and packed in an atmosphere in which air is replaced in whole...

  15. 21 CFR 169.115 - French dressing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... emulsified viscous fluid food prepared from vegetable oil(s) and one or both of the acidifying ingredients... this section may also be used. The vegetable oil(s) used may contain an optional crystallization... vegetable oil. French dressing may be mixed and packed in an atmosphere in which air is replaced in whole...

  16. Colour Vision: Understanding #TheDress.

    PubMed

    Brainard, David H; Hurlbert, Anya C

    2015-06-29

    A widely-viewed image of a dress elicits striking individual variation in colour perception. Experiments with multiple variants of the image suggest that the individual differences may arise through the action of visual mechanisms that normally stabilise object colour. PMID:26126278

  17. Student Dress Codes and Uniforms. Research Brief

    ERIC Educational Resources Information Center

    Johnston, Howard

    2009-01-01

    According to an Education Commission of the States "Policy Report", research on the effects of dress code and school uniform policies is inconclusive and mixed. Some researchers find positive effects; others claim no effects or only perceived effects. While no state has legislatively mandated the wearing of school uniforms, 28 states and the…

  18. A Dressed Spin Qubit in Silicon

    NASA Astrophysics Data System (ADS)

    Laucht, Arne; Kalra, Rachpon; Dehollain, Juan; Simmons, Stephanie; Muhonen, Juha; Mohiyaddin, Fahd; Freer, Solomon; Hudson, Fay; Itoh, Kohei; Jamieson, David; McCallum, Jeff; Dzurak, Andrew; Morello, Andrea

    Coherent dressing of a quantum two-level system has been demonstrated on a variety of systems, including atoms, self-assembled quantum dots, and superconducting quantum bits, and can be demonstrated by measuring Rabi oscillations, or a Mollow triplet in the spectrum. It can be used to gain access to a new quantum system with improved properties - a different and tunable level splitting, faster and easier control, and longer coherence times. In our work we investigate the properties of the dressed, donor-bound electron spin in silicon, and probe its potential for the use as quantum bit in scalable architectures. Here, the two dressed spin-polariton levels constitute the quantum bit. The dressed qubit can be coherently driven with an oscillating magnetic field, an oscillating electric field, by frequency modulating the driving field, or by a simple detuning pulse. We measure coherence times of T2* = 2.4 ms and T2 = 9 ms (Hahn echo), one order of magnitude longer than those of the undressed qubit. This research was funded by the ARC Centre of Excellence for Quantum Computation and Communication Technology (Project Number CE110001027) and the US Army Research Office (W911NF-13-1-0024).

  19. Scattering of dressed nucleons in nuclear matter

    NASA Astrophysics Data System (ADS)

    Dickhoff, W. H.

    1998-11-01

    The scattering of dressed nucleons in nuclear matter is studied. By casting the conventional asymptotic analysis of scattering in free space in the language of the two-body propagator, it becomes possible to develop modifications of this analysis due to the dressing of the scattering nucleons in the medium. While the scattering energy singles out a unique (on-shell) momentum characterizing the relative wave function of free or mean-field nucleons, this uniqueness is no longer maintained for dressed nucleons. The resulting distribution of momenta in the relative wave function leads to a localization in coordinate space of the influence of the scattering process which can be expressed as a healing of the wave function to the noninteracting one. An analytic approximation to the noninteracting propagator of the dressed nucleons is utilized to illustrate these points. The localization of the scattered wave implies that the particles no longer ``remember'' their scattering event beyond some finite distance. This feature suggests that the strict notion of a cross section in the medium is a tenuous concept. Approximate expressions are developed to characterize the strength of the interaction in the medium in terms of phase shifts and cross sections to facilitate comparisons with results of calculations involving mean-field nucleons.

  20. Compatibility of a protein topical gel with wound dressings.

    PubMed

    Ji, Junyan A; Borisov, Oleg; Ingham, Erika; Ling, Victor; Wang, Y John

    2009-02-01

    The compatibility between several dressing materials and a recombinant human vascular endothelial growth factor (rhVEGF) topical methylcellulose gel formulation was investigated. The dressings being studied were Adaptic, Non-stick Dressing, Conformant 2, Opsite and Tegapore. The criteria to select a compatible dressing include protein stability, absence of leachables from the dressing, and ability to retain gel on wound. An LC-MS method with sample treatment using cellulase was developed to determine protein oxidation in gel formulations. Results showed that rhVEGF was significantly oxidized by Adaptic dressing in 24 h. Protein oxidation was likely due to the peroxides, as determined by FOX assay, released into the protein solution from the dressing. Furthermore, Adaptic dressing caused protein adsorption loss, formation of high MW protein adducts, and released leachables as determined by RP-HPLC, LC-MS, and SEC. No protein oxidation or loss was observed after exposure to the other four alternative dressings. However, unknown leachables were detected in the presence of Opsite and Non-stick Dressing. The pore sizes of the Conformant 2 and Non-stick dressings were too large to hold the topical gel within the wound area, making them unsuitable for patient use. No rhVEGF bioactivity loss was observed in the presence of Tegapore. In conclusion, Tegapore was considered suitable for the rhVEGF topical gel.

  1. Inductively guided circuits for ultracold dressed atoms.

    PubMed

    Sinuco-León, German A; Burrows, Kathryn A; Arnold, Aidan S; Garraway, Barry M

    2014-01-01

    Recent progress in optics, atomic physics and material science has paved the way to study quantum effects in ultracold atomic alkali gases confined to non-trivial geometries. Multiply connected traps for cold atoms can be prepared by combining inhomogeneous distributions of DC and radio-frequency electromagnetic fields with optical fields that require complex systems for frequency control and stabilization. Here we propose a flexible and robust scheme that creates closed quasi-one-dimensional guides for ultracold atoms through the 'dressing' of hyperfine sublevels of the atomic ground state, where the dressing field is spatially modulated by inductive effects over a micro-engineered conducting loop. Remarkably, for commonly used atomic species (for example, (7)Li and (87)Rb), the guide operation relies entirely on controlling static and low-frequency fields in the regimes of radio-frequency and microwave frequencies. This novel trapping scheme can be implemented with current technology for micro-fabrication and electronic control. PMID:25348163

  2. Quantum complex sine-Gordon dressed boundaries

    NASA Astrophysics Data System (ADS)

    Bowcock, P.; Umpleby, J. M.

    2008-11-01

    In this paper we investigate the quantum reflection factor for the CSG dressed boundary, previously constructed by dressing the Dirichlet boundary with the integrable CSG defect [1]. We analyse classical bound states and use semi-classical methods to investigate the quantum boundary spectrum. We conjecture a fully quantum reflection matrix for a particle reflecting from an unexcited boundary. By using the reflection and boundary bootstrap equations, the reflection matrix for a charge Q = +n soliton reflecting from the mth excited boundary is constructed. Evidence supporting our conjecture is given by checking that the bootstrap closes and that the reflection matrices agrees with known results in the classical limit. A partial analysis of the poles in the reflection matrices which arise from Coleman-Thun diagrams is given.

  3. [Diabetic, neuropathic, arteriopathic foot and dressing choice].

    PubMed

    Lowe, S; Kayoumi, M

    2012-11-14

    The definition for the diabetic foot is infection, ulceration or destruction of deep tissues of the foot associated with neuropathy or peripheral vascular disease in the lower extremity of people with diabetes. Non-diabetic patients may suffer the same risks when neuropathy and arteriopathy are present. Knowing that 85% of amputations are preceded by foot ulcers, prevention is primordial. At the onset of an ulcer, immediate treatment must be undertaken and preferably by an interdisciplinary team. Delayed healing and increased risk of infection are often due to an associated vascular disease. While the array of dressings is expansive there is no «gold standard» treatment or «miracle dressing» described for foot ulcers. The management consists of wound analysis, debridement, woundcare and especially offloading.

  4. Efficacy of Dressing with Absorbent Foam versus Dressing with Gauze in Prevention of Tracheostomy Site Infection

    PubMed Central

    Ahmadinegad, Mehdi; Lashkarizadeh, Mohammad Reza; Ghahreman, Minoo; Shabani, Mohammad; Mokhtare, Mahsa

    2014-01-01

    Background Tracheostomy site infection can cause numerous problems. Absorbent foam dressing may be able to prevent proliferation of infectious microorganisms by absorbing the tracheostomy stoma exudate. This study aimed to compare the efficacy of absorbent foam with gauze dressing for prevention of tracheostomy site infection. Materials and Methods In this double-blind randomized clinical trial, 80 patients (18 to 60 years) hospitalized in the intensive care unit (ICU) due to severe head injury were randomly divided into two groups and early tracheostomy was done for them during the first 2 days. In the first group, gauze was used as tracheostomy site dressing, while in the second, absorbent foam, was placed. Tracheostomy site was checked daily for any sign of infection and samples were taken from the stoma for culture in case of presence of any sign of infection. Results Of a total of 80, 11 had tracheostomy site infection (13.75%), including 7 (17.5%) in the gauze group and 4 (10%) in the foam group. The difference in this regard between the two groups was not significant (P=0.051). Also, the dominant strains in the culture of gauze group were hospital-acquired Gram-negative bacteria (particularly Acinetobacter), while in the foam group, Gram-positives and more commonly Staphylococcus epidermidis were found. Conclusion Absorbent foam dressing is not superior to gauze dressings for prevention of tracheostomy site infection. PMID:25506371

  5. Dressings and Products in Pediatric Wound Care

    PubMed Central

    King, Alice; Stellar, Judith J.; Blevins, Anne; Shah, Kara Noelle

    2014-01-01

    Significance: The increasing complexity of medical and surgical care provided to pediatric patients has resulted in a population at significant risk for complications such as pressure ulcers, nonhealing surgical wounds, and moisture-associated skin damage. Wound care practices for neonatal and pediatric patients, including the choice of specific dressings or other wound care products, are currently based on a combination of provider experience and preference and a small number of published clinical guidelines based on expert opinion; rigorous evidence-based clinical guidelines for wound management in these populations is lacking. Recent Advances: Advances in the understanding of the pathophysiology of wound healing have contributed to an ever-increasing number of specialized wound care products, most of which are predominantly marketed to adult patients and that have not been evaluated for safety and efficacy in the neonatal and pediatric populations. This review aims to discuss the available data on the use of both more traditional wound care products and newer wound care technologies in these populations, including medical-grade honey, nanocrystalline silver, and soft silicone-based adhesive technology. Critical Issues: Evidence-based wound care practices and demonstration of the safety, efficacy, and appropriate utilization of available wound care dressings and products in the neonatal and pediatric populations should be established to address specific concerns regarding wound management in these populations. Future Directions: The creation and implementation of evidence-based guidelines for the treatment of common wounds in the neonatal and pediatric populations is essential. In addition to an evaluation of currently marketed wound care dressings and products used in the adult population, newer wound care technologies should also be evaluated for use in neonates and children. In addition, further investigation of the specific pathophysiology of wound healing in

  6. DRESS syndrome: à propos de trois observations

    PubMed Central

    Chebbi, Wafa; Souissi, Jihed; Chelli, Jihène; Larbi, Fatma; Zantour, Baha; Habib Sfar, Mohamed

    2014-01-01

    Le syndrome d'hypersensibilité médicamenteuse ou Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) est une toxidermie rare mais sévère. Nous rapportons trois observations de DRESS syndromes secondaires à la prise de carbamazipine dans deux cas et de salazopyrine dans un cas. Le délai moyen entre la prise médicamenteuse et la survenue du DRESS syndrome était de six semaines. Le médicament incriminé était arrêté d'une façon définitive dans tous les cas. Une corticothérapie par voie générale était instaurée chez tous les patients devant l'atteinte hépatique sévère. L’évolution était favorable avec disparation des lésions cutanées et normalisation du bilan hépatique. Le diagnostic du syndrome DRESS doit être évoqué devant un tableau associant une éruption fébrile et des signes systémiques faisant suite à une prise médicamenteuse. La précocité du diagnostic est fondamentale pour l'arrêt définitif des médicaments suspects. Le traitement n'est pas bien codifié mais repose actuellement sur la corticothérapie générale. PMID:25810802

  7. Quantum dress for a naked singularity

    NASA Astrophysics Data System (ADS)

    Casals, Marc; Fabbri, Alessandro; Martínez, Cristián; Zanelli, Jorge

    2016-09-01

    We investigate semiclassical backreaction on a conical naked singularity space-time with a negative cosmological constant in (2 + 1)-dimensions. In particular, we calculate the renormalized quantum stress-energy tensor for a conformally coupled scalar field on such naked singularity space-time. We then obtain the backreacted metric via the semiclassical Einstein equations. We show that, in the regime where the semiclassical approximation can be trusted, backreaction dresses the naked singularity with an event horizon, thus enforcing (weak) cosmic censorship.

  8. Antigen Presentation by MHC-Dressed Cells

    PubMed Central

    Nakayama, Masafumi

    2015-01-01

    Professional antigen-presenting cells (APCs) such as conventional dendritic cells (DCs) process protein antigens to MHC-bound peptides and then present the peptide–MHC complexes to T cells. In addition to this canonical antigen presentation pathway, recent studies have revealed that DCs and non-APCs can acquire MHC class I (MHCI) and/or MHC class II (MHCII) from neighboring cells through a process of cell–cell contact-dependent membrane transfer called trogocytosis. These MHC-dressed cells subsequently activate or regulate T cells via the preformed antigen peptide–MHC complexes without requiring any further processing. In addition to trogocytosis, intercellular transfer of MHCI and MHCII can be mediated by secretion of membrane vesicles such as exosomes from APCs, generating MHC-dressed cells. This review focuses on the physiological role of antigen presentation by MHCI- or MHCII-dressed cells, and also discusses differences and similarities between trogocytosis and exosome-mediated transfer of MHC. PMID:25601867

  9. Dressed active particles in spherical crystals.

    PubMed

    Yao, Zhenwei

    2016-08-17

    We investigate the dynamics of an active particle in two-dimensional spherical crystals, which provide an ideal environment to illustrate the interplay between active particles and crystallographic defects. A moving active particle is observed to be surrounded by localized topological defects, becoming a dressed active particle. Such a physical picture characterizes both the lattice distortion around the moving particle and the healing of the distorted lattice in its trajectory. We find that the dynamical behaviors of an active particle in both random and ballistic motions uniformly conform to this featured scenario, whether the particle is initially a defect or not. We further observe that the defect pattern around a dressed ballistic active particle randomly oscillates between two well-defined wing-like defect motifs regardless of its speed. The established physical picture of dressed active particles in this work partially deciphers the complexity of the intriguing nonequilibrium behaviors in active crystals, and opens the promising possibility of introducing the activity to engineer defects, which has strong connections with the design of materials.

  10. Role of Surgical Dressings in Total Joint Arthroplasty: A Randomized Controlled Trial.

    PubMed

    Springer, Bryan D; Beaver, Walter B; Griffin, William L; Mason, J Bohannon; Odum, Susan M

    2015-09-01

    We conducted a randomized controlled trial to compare efficacy of an occlusive antimicrobial barrier dressing and a standard surgical dressing in patients who underwent primary total joint arthroplasty. Two hundred sixty-two patients were randomized to receive either an occlusive dressing or a standard dressing. Wounds were closed in identical fashion. Outcomes included wound complications, dressing changes, and patient satisfaction. With use of occlusive dressing (vs standard dressing), wound complications (including skin blistering) were significantly (P = 0.15) reduced; there were significantly (P < .0001) fewer dressing changes; and patient satisfaction was significantly (P < .0001) higher. Use of occlusive dressings can reduce wound complications and promote wound healing after total joint arthroplasty.

  11. A vapour-permeable film dressing used on superficial wounds.

    PubMed

    Meuleneire, Frans

    2014-08-12

    Films are an extremely versatile dressing type that can be effectively used in the treatment of many superficial wounds, such as skin grafts, surgical wounds and superficial burns; they provide an optimal moist environment to promote healing, act as a barrier to bacteria, and afford protection from urine and faecal contamination. Unfortunately, many film dressings are difficult to handle and use traditional adhesives, which can cause trauma to the wound and surrounding skin, as well as increased wound pain at dressing removal. Mepitel® Film is a new, easy-to-use wound dressing designed with Safetac® technology that helps to minimise dressing-related trauma and pain and assist undisturbed wound healing. This article presents case studies that examine Mepitel Film's use on a variety of wounds, and reviews the findings of research that was undertaken to evaluate the benefits of using this recently developed dressing.

  12. The local treatment and available dressings designed for chronic wounds.

    PubMed

    Skórkowska-Telichowska, Katarzyna; Czemplik, Magdalena; Kulma, Anna; Szopa, Jan

    2013-04-01

    The great diversity of wounds and the broad range of available dressings complicate the selection of proper chronic wound treatment. Choosing the right treatment is the essential step in the healing process. In this review, we focus on chronic nonhealing ulcers, which are a critical problem in clinical practice, and current knowledge about persistent wound care. Here, we present the objectives of local treatment with description of several types of dressings and their ingredients, features, indications, and contraindications. These include hydrocolloid, alginate, hydrogel, and dextranomer dressings; polyurethane foam and membrane dressings; semipermeable polyurethane membrane dressings; and TenderWet (Hartmann, Rock Hill, SC) and flax dressings. There is also a brief section on the use of other alternative wound-healing accelerators, such as platelet-rich plasma and light-emitting diode therapy. PMID:21982060

  13. Evaluation of an alginate dressing for pressure ulcers.

    PubMed

    Fowler, E; Papen, J C

    1991-08-01

    Pressure ulcers that secrete moderate to large amounts of fluid often cause leakage from under dressings, odor, staining of clothing, denuding of the skin, and pain. Two highly absorbent dressings derived from seaweed have been introduced into the U.S. market for use in the management of exuding wounds. Severely debilitated patients with full-thickness pressure ulcers were treated for one week to three months with one of these alginate dressings (Kaltostat). The handling and performance characteristics of the dressing are discussed.

  14. The role of dressings in the prevention of pressure ulcers.

    PubMed

    Brown, Julie

    2016-08-11

    Pressure ulceration is a significant global healthcare problem and represents a considerable burden on healthcare resources. Within the literature an increasing number of studies have examined the role prophylactic dressings play in redistributing pressure and helping to protect the skin from the effects of friction and shear. The use of dressings to prevent pressure ulcers may be considered a controversial issue, as previous opinion has been that dressings do not reduce the effects of pressure. This article will critically evaluate the literature to examine the role dressings play in the prevention of pressure ulceration. PMID:27523773

  15. Redoable tie-over dressing using multiple loop silk threads.

    PubMed

    Jo, Hyeon Jong; Kim, Jun Sik; Kim, Nam Gyun; Lee, Kyung Suk; Choi, Jae Hoon

    2013-05-01

    After skin grafting, to prevent hematoma or seroma collection at the graft site, a tie-over dressing has been commonly used. However, although the conventional tie-over dressing by suture is a useful method for securing a graft site, refixation is difficult when repeated tie-over dressing is needed. Therefore, we recommend a redoable tie-over dressing technique with multiple loops threads and connecting silk threads. After the raw surface of each of our cases was covered with a skin graft, multiple loop silk thread attached with nylon at the skin graft margin. We applied the ointment gauze and wet cotton/fluffy gauze over the skin graft, then fixed the dressing by connecting cross-counter multiple loop thread with connecting silk threads. When we opened the tie-over dressing by cutting the connecting silk threads, we repeated the tie-over dressing with the same method. The skin graft was taken successfully without hematoma or seroma collection or any other complications. In conclusion, we report a novel tie-over dressing enabling simple fixation of the dressing to maintain proper tension for wounds that require repetitive fixation. Further, with this reliable method, the skin grafts were well taken.

  16. Constructing medical social authority on dress in Victorian Canada.

    PubMed

    O'Connor, Eileen

    2008-01-01

    During the late-Victorian period, campaigns to "reform" middle-class women's dress were grounded in discourses on health, eugenics, declining birth rates, comfort, and aesthetics. In Britain, the United States and Germany, organized "dress reform" movements emerged in the latter half of the 19th century, while in Canada the campaign was led primarily by physicians through public health education. This article explores the discussion on women's dress in public health literature in Canadian circulation between 1860-1900 and interprets findings within a feminist poststructuralist framework that posits the understanding of women's bodies and gender regulation to be central to knowledge construction on women's dress.

  17. Dress Nicer = Know More? Young Children’s Knowledge Attribution and Selective Learning Based on How Others Dress

    PubMed Central

    McDonald, Kyla P.; Ma, Lili

    2015-01-01

    This research explored whether children judge the knowledge state of others and selectively learn novel information from them based on how they dress. The results indicated that 4- and 6-year-olds identified a formally dressed individual as more knowledgeable about new things in general than a casually dressed one (Study 1). Moreover, children displayed an overall preference to seek help from a formally dressed individual rather than a casually dressed one when learning about novel objects and animals (Study 2). These findings are discussed in relation to the halo effect, and may have important implications for child educators regarding how instructor dress might influence young students’ knowledge attribution and learning preferences. PMID:26636980

  18. Prototype Development of a Responsive Emotive Sensing System (DRESS) to aid older persons with dementia to dress independently

    PubMed Central

    Mahoney, Diane Feeney; Burleson, Winslow; Lozano, Cecil; Ravishankar, Vijay; Mahoney, Edward Leo

    2015-01-01

    Background Prior research has critiqued the lack of attention to the stressors associated with dementia related dressing issues, stigmatizing patient clothing, and wearable technology challenges. This paper describes the conceptual development and feasibility testing of an innovative ‘smart dresser’ context aware affective system (DRESS) to enable dressing by people with moderate memory loss through individualized audio and visual task prompting in real time. Methods Mixed method feasibility study involving qualitative focus groups with 25 Alzheimer’s family caregivers experiencing dressing difficulties to iteratively inform system design and a quantitative usability trial with 10 healthy subjects in a controlled laboratory setting to assess validity of technical operations. Results Caregivers voiced the need for tangible dressing assistance to reduce their frustration from time spent in repetitive cueing and power struggles over dressing. They contributed 6 changes that influenced the prototype development, most notably adding a dresser top iPad to mimic a familiar ‘TV screen’ for the audio and visual cueing. DRESS demonstrated promising overall functionality, however the validity of identification of dressing status ranged from 0% for the correct pants dressing to 100% for all shirts dressing scenarios. Adjustments were made to the detection components of the system raising the accuracy of detection of all acted dressing scenarios for pants from 50% to 82%. Conclusions Findings demonstrate family caregiver acceptability of the proposed system, the successful interoperability of the built system’s components, and the system’s ability to interpret correct and incorrect dressing actions in controlled laboratory simulations. Future research will advance the system to the alpha stage and subsequent testing with end users in real world settings. PMID:26321895

  19. Economics of pressure-ulcer care: review of the literature on modern versus traditional dressings.

    PubMed

    San Miguel, L; Torra i Bou, J E; Verdú Soriano, J

    2007-01-01

    Published evidence suggests that some of the benefits of modern dressings--longer wear times and less frequent dressing changes--make them more cost-effective than traditional gauze dressings in pressure ulcer management.

  20. One Dress, Two Dress: Dialectal Influence on Spelling of English Words among Kindergarten Children in Singapore

    ERIC Educational Resources Information Center

    Dixon, L. Quentin; Zhao, Jing; Joshi, R. Malatesha

    2012-01-01

    The present study examined the influence of Singapore Colloquial English (SCE) on Standard English word spelling through a plural formation task of four words ("man", "tooth", "dress" and "child") among 168 Singaporean bilingual children with Chinese background. It was found that "dropping the plural" was the most prevalent type of error. Poor…

  1. An Inexpensive Bismuth-Petrolatum Dressing for Treatment of Burns

    PubMed Central

    Chattopadhyay, Arhana; Chang, Kathleen; Nguyen, Khoa; Galvez, Michael G.; Legrand, Anais; Davis, Christopher; McGoldrick, Rory; Long, Chao; Pham, Hung

    2016-01-01

    Background: Xeroform remains the current standard for treating superficial partial-thickness burns but can be prohibitively expensive in developing countries with prevalent burn injuries. This study (1) describes the production of an alternative low-cost dressing and (2) compares the alternative dressing and Xeroform using the metrics of cost-effectiveness, antimicrobial activity, and biocompatibility in vitro, and wound healing in vivo. Methods: To produce the alternative dressing, 3% bismuth tribromophenate powder was combined with petroleum jelly by hand and applied to Kerlix gauze. To assess cost-effectiveness, the unit costs of Xeroform and components of the alternative dressing were compared. To assess antimicrobial properties, the dressings were placed on agar plated with Escherichia coli and the Kirby-Bauer assay performed. To assess biocompatibility, the dressings were incubated with human dermal fibroblasts and cells stained with methylene blue. To assess in vivo wound healing, dressings were applied to excisional wounds on rats and the rate of re-epithelialization calculated. Results: The alternative dressing costs 34% of the least expensive brand of Xeroform. Antimicrobial assays showed that both dressings had similar bacteriostatic effects. Biocompatibility assays showed that there was no statistical difference (P < 0.05) in the cytotoxicity of Xeroform, alternative dressing, and Kerlix gauze. Finally, the in vivo healing model showed no statistical difference (P < 0.05) in mean re-epithelialization time between Xeroform (13.0 ± 1.6 days) and alternative dressing (13.5 ± 1.0 days). Conclusions: Xeroform is biocompatible, reduces infection, and enhances healing of burn wounds by preventing desiccation and mechanical trauma. Handmade petrolatum gauze may be a low-cost replacement for Xeroform. Future studies will focus on clinical trials in burn units. PMID:27482485

  2. Large energy superpositions via Rydberg dressing

    NASA Astrophysics Data System (ADS)

    Khazali, Mohammadsadegh; Lau, Hon Wai; Humeniuk, Adam; Simon, Christoph

    2016-08-01

    We propose to create superposition states of over 100 strontium atoms in a ground state or metastable optical clock state using the Kerr-type interaction due to Rydberg state dressing in an optical lattice. The two components of the superposition can differ by an order of 300 eV in energy, allowing tests of energy decoherence models with greatly improved sensitivity. We take into account the effects of higher-order nonlinearities, spatial inhomogeneity of the interaction, decay from the Rydberg state, collective many-body decoherence, atomic motion, molecular formation, and diminishing Rydberg level separation for increasing principal number.

  3. Identification of Workplace Dress by Low-Income Job Seekers

    ERIC Educational Resources Information Center

    Saiki, Diana

    2013-01-01

    The author examined how low-income job seekers participating in a workplace dress program identified traditional business and business casual dress. Seventy low-income job seekers identified clothing items as traditional business (e.g., suits, ties), similar to identifications made by professionals and image consultants in previous literature.…

  4. Inhibition of Pseudomonas aeruginosa biofilm formation on wound dressings

    PubMed Central

    Brandenburg, Kenneth S.; Calderon, Diego F.; Kierski, Patricia R.; Brown, Amanda L.; Shah, Nihar M.; Abbott, Nicholas L.; Schurr, Michael J.; Murphy, Christopher J.; McAnulty, Jonathan F.; Czuprynski, Charles J.

    2016-01-01

    Chronic non-healing skin wounds often contain bacterial biofilms that prevent normal wound healing and closure and present challenges to the use of conventional wound dressings. We investigated inhibition of Pseudomonas aeruginosa biofilm formation, a common pathogen of chronic skin wounds, on a commercially available biological wound dressing. Building upon prior reports, we examined whether the amino acid tryptophan would inhibit P. aeruginosa biofilm formation on the 3-dimensional surface of the biological dressing. Bacterial biomass and biofilm polysaccharides were quantified using crystal violet staining or an enzyme linked lectin, respectively. Bacterial cells and biofilm matrix adherent to the wound dressing were visualized through scanning electron microscopy. D-/L-tryptophan inhibited P. aeruginosa biofilm formation on the wound dressing in a dose dependent manner and was not directly cytotoxic to immortalized human keratinocytes although there was some reduction in cellular metabolism or enzymatic activity. More importantly, D-/L-tryptophan did not impair wound healing in a splinted skin wound murine model. Furthermore, wound closure was improved when D-/L-tryptophan treated wound dressing with P. aeruginosa biofilms were compared with untreated dressings. These findings indicate that tryptophan may prove useful for integration into wound dressings to inhibit biofilm formation and promote wound healing. PMID:26342168

  5. Moral Crisis in Higher Institutions and the Dress Code Phenomenon

    ERIC Educational Resources Information Center

    Fayokun, K. O.; Adedeji, S. O.; Oyebade, S. A.

    2009-01-01

    This article reviewed the case of indecent dressing among the youth of today especially on the universities campuses, which has forced the authorities of those institutions to enact dress codes to stem the tide and restore high moral standards, integrity and decency. Whether this bid was successful or not was another thing which was a function of…

  6. Fashion as Argument: Nineteenth-Century Dress Reform.

    ERIC Educational Resources Information Center

    Torrens, Kathleen M.

    1999-01-01

    Examines the place of the body in the dress-reform movement, a social movement that focused on fashion as a vehicle for achieving social and political equality. Discusses how fashion became one arena in which definitions of gender were contested. Suggests the dress-reform movement's failure in redefining femininity indicates the depth of…

  7. The disc dressing for local irrigation of experimental burn wounds.

    PubMed

    Kaufman, T; Levin, M; Eichenlaub, E H; Hurwitz, D J; Futrell, J W

    1984-12-01

    The newly designed disc dressing permits the surface of experimental burn wounds to be irrigated with liquid therapeutic agents without the need for frequent dressing changes. This approach is simple to handle, reduces the risk of trauma or contamination of the wound, and is not time consuming.

  8. Inhibition of Pseudomonas aeruginosa biofilm formation on wound dressings.

    PubMed

    Brandenburg, Kenneth S; Calderon, Diego F; Kierski, Patricia R; Brown, Amanda L; Shah, Nihar M; Abbott, Nicholas L; Schurr, Michael J; Murphy, Christopher J; McAnulty, Jonathan F; Czuprynski, Charles J

    2015-01-01

    Chronic nonhealing skin wounds often contain bacterial biofilms that prevent normal wound healing and closure and present challenges to the use of conventional wound dressings. We investigated inhibition of Pseudomonas aeruginosa biofilm formation, a common pathogen of chronic skin wounds, on a commercially available biological wound dressing. Building on prior reports, we examined whether the amino acid tryptophan would inhibit P. aeruginosa biofilm formation on the three-dimensional surface of the biological dressing. Bacterial biomass and biofilm polysaccharides were quantified using crystal violet staining or an enzyme linked lectin, respectively. Bacterial cells and biofilm matrix adherent to the wound dressing were visualized through scanning electron microscopy. D-/L-tryptophan inhibited P. aeruginosa biofilm formation on the wound dressing in a dose dependent manner and was not directly cytotoxic to immortalized human keratinocytes although there was some reduction in cellular metabolism or enzymatic activity. More importantly, D-/L-tryptophan did not impair wound healing in a splinted skin wound murine model. Furthermore, wound closure was improved when D-/L-tryptophan treated wound dressing with P. aeruginosa biofilms were compared with untreated dressings. These findings indicate that tryptophan may prove useful for integration into wound dressings to inhibit biofilm formation and promote wound healing.

  9. Inhibition of Pseudomonas aeruginosa biofilm formation on wound dressings.

    PubMed

    Brandenburg, Kenneth S; Calderon, Diego F; Kierski, Patricia R; Brown, Amanda L; Shah, Nihar M; Abbott, Nicholas L; Schurr, Michael J; Murphy, Christopher J; McAnulty, Jonathan F; Czuprynski, Charles J

    2015-01-01

    Chronic nonhealing skin wounds often contain bacterial biofilms that prevent normal wound healing and closure and present challenges to the use of conventional wound dressings. We investigated inhibition of Pseudomonas aeruginosa biofilm formation, a common pathogen of chronic skin wounds, on a commercially available biological wound dressing. Building on prior reports, we examined whether the amino acid tryptophan would inhibit P. aeruginosa biofilm formation on the three-dimensional surface of the biological dressing. Bacterial biomass and biofilm polysaccharides were quantified using crystal violet staining or an enzyme linked lectin, respectively. Bacterial cells and biofilm matrix adherent to the wound dressing were visualized through scanning electron microscopy. D-/L-tryptophan inhibited P. aeruginosa biofilm formation on the wound dressing in a dose dependent manner and was not directly cytotoxic to immortalized human keratinocytes although there was some reduction in cellular metabolism or enzymatic activity. More importantly, D-/L-tryptophan did not impair wound healing in a splinted skin wound murine model. Furthermore, wound closure was improved when D-/L-tryptophan treated wound dressing with P. aeruginosa biofilms were compared with untreated dressings. These findings indicate that tryptophan may prove useful for integration into wound dressings to inhibit biofilm formation and promote wound healing. PMID:26342168

  10. Umbilical Negative Pressure Dressing for Transumbilical Appendectomy in Childern

    PubMed Central

    Kundu, Neilendu; Guerron, Alfredo D.; Garland, Mary M.; Gaffley, Michaela W. G.; Worley, Sarah; Knight, Colin G.

    2016-01-01

    Background and Objectives: Transumbilical laparoscopic-assisted appendectomy (TULAA) carries a high risk for surgical site infection. We investigated the effect of a bio-occlusive umbilical vacuum dressing on wound infection rates after TULAA for patients with acute appendicitis and compared to it with a conventional 3-port appendectomy with a nonvacuum dressing. Methods: This study was a retrospective chart review of 1377 patients (2–20 years) undergoing laparoscopic appendectomy for acute appendicitis in 2 tertiary care referral centers from January 2007 through December 2012. Twenty-two different operative technique/dressing variations were documented. The 6 technique/dressing groups with >50 patients were assessed, including a total of 1283 patients. Results: The surgical site infection rate of the 220 patients treated with TULAA and application of an umbilical vacuum dressing with dry gauze is 1.8% (95% CI, 0.0–10.3%). This compares to an infection rate of 4.1% (95% CI, 1.3–10.5%) in 97 patients with dry dressing without vacuum. In the 395 patients who received an umbilical vacuum dressing with gauze and bacitracin, the surgical site infection rate was found to be 4.3% (95% CI, 2.7–6.8%). Conclusions: Application of an umbilical negative-pressure dressing with dry gauze lowers the rate of umbilical site infections in patients undergoing transumbilical laparoscopic-assisted appendectomy for acute appendicitis. PMID:27807398

  11. Civil Behavior, Safe-School Planning, and Dress Codes

    ERIC Educational Resources Information Center

    Studak, Cathryn M.; Workman, Jane E.

    2007-01-01

    This research examined news reports in order to identify incidents that precipitated dress code revisions. News reports were examined within the framework of rules for civil behavior. Using key words "school dress codes" and "violence," LEXIS/NEXIS was used to access 104 articles from 44 U.S. newspapers from December 3, 2004 to December 2, 2005.…

  12. Connective tissue response to periodontal dressing.

    PubMed

    Nezwek, R A; Caffesse, R G; Bergenholtz, A; Nasjleti, C E

    1980-09-01

    The effects of three periodontal dressings (Coe-Pak, PPC, Perio Putty) upon subcutaneous tissues in 26 Sprague-Dawley rats were investigated. The three dressings, and a control (Teflon), were placed into polyethylene tubes. Two tubes per animal were implanted on either side of the dorsal midline area. After 14 days the specimens were retrieved and prepared for histological examination. Three methods of scoring were utilized for evaluation. First, a system evaluating the overall number of inflammatory cells, connective tissue capsule thickness, and the vascular changes produced; second, an inflammatory cell count, the Inflammatory Index (I.I), computing the inflammatory cells in a particular field of view for each material; and third, a Reaction Spread Index (R.S.I.) comparing the distance of the spread of the inflammatory reaction into the connective tissues. Statistical analysis of the data was carried out utilizing the Chi-square test and analysis of variance. While the three scoring systems utilized did result in some comparative variation in reactions, the overall order of decreasing severity was always PPC, Coe-Pak, Perio Putty, and Teflon.

  13. Novel silk fibroin/elastin wound dressings.

    PubMed

    Vasconcelos, Andreia; Gomes, Andreia C; Cavaco-Paulo, Artur

    2012-08-01

    Silk fibroin (SF) and elastin (EL) scaffolds were successfully produced for the first time for the treatment of burn wounds. The self-assembly properties of SF, together with the excellent chemical and mechanical stability and biocompatibility, were combined with elastin protein to produce scaffolds with the ability to mimic the extracellular matrix (ECM). Porous scaffolds were obtained by lyophilization and were further crosslinked with genipin (GE). Genipin crosslinking induces the conformational transition from random coil to β-sheet of SF chains, yielding scaffolds with smaller pore size and reduced swelling ratios, degradation and release rates. All results indicated that the composition of the scaffolds had a significant effect on their physical properties, and that can easily be tuned to obtain scaffolds suitable for biological applications. Wound healing was assessed through the use of human full-thickness skin equivalents (EpidermFT). Standardized burn wounds were induced by a cautery and the best re-epithelialization and the fastest wound closure was obtained in wounds treated with 50SF scaffolds; these contain the highest amount of elastin after 6 days of healing in comparison with other dressings and controls. The cytocompatibility demonstrated with human skin fibroblasts together with the healing improvement make these SF/EL scaffolds suitable for wound dressing applications.

  14. IV 3000 Dressing for Fingertip Injury: Management and Discussion.

    PubMed

    Kurian, Susan; Davis, Meghan; Fazi, Alyssa; McClellan, W Thomas

    2016-01-01

    An active, right hand dominant. 86-year-old male presented with transverse amputation of the right ring finger just distal to the DIP joint. Conservative management was recommended in order to preserve digit length, mobility, and the DIP joint. The IV3000 semipermeable dressing was utilized as the primary treatment. The clear adhesive dressing has a high moisture vapor transmission rate that facilitates creation of a suitable wound microenvironment. The digit showed significant epithelialization and mobility at two weeks post-injury and was healed with full range of motion at both the DIP and PIP joints by week six. There were no complications from use of the IV3000 dressing, and both healing time and pain during dressing change are improved over alternative dressings like gauze.

  15. A new postoperative otoplasty dressing technique using cyanoacrylate tissue adhesives.

    PubMed

    Vetter, Miriam; Foehn, Matthias; Wedler, Volker

    2010-04-01

    There are many techniques for cosmetic surgery of the ears and also many different procedures for postoperative treatment. The postoperative dressing is described as important for a successful outcome. We present our method of postoperative dressing in the form of liquid bonding. Cyanoacrylate tissue adhesives as liquid bonding agents are used for fixation of the pinna at the mastoid area. After 10-14 days the bonding can be easily removed. No huge dressings, tapes, or plasters are necessary. The patients are satisfied with the light dressing; they do not feel ashamed to appear in public. We have found this dressing technique to be simple and economical, especially because of the use of the bonding for skin closure before. It can be used after otoplasty with an anterior or a posterior approach.

  16. The analgesic effect of odour and music upon dressing change.

    PubMed

    Kane, F M A; Brodie, E E; Coull, A; Coyne, L; Howd, A; Milne, A; Niven, C C; Robbins, R

    Vascular wounds may require frequent dressing changes over a long period of time, often involving pain, which may not be adequately controlled with conventional analgesia. Complementary analgesia may be beneficial as an adjunctive therapy. This pilot study presented eight patients with two odour therapies, lavender and lemon, two music therapies, relaxing and preferred music and a control condition, during vascular wound dressing changes. Although the therapies did not reduce the pain intensity during the dressing change there was a significant reduction in pain intensity for the lavender therapy and a reduction in pain intensity for the relaxing music therapy after the dressing change. This supports the use of these complementary therapies, which are inexpensive, easy to administer and have no known side effects, as adjunctive analgesia in this patient population. Earlier administration before dressing change may enhance these effects. Further research is required to ascertain why certain complementary therapies are more effective than others at relieving pain.

  17. Wound dressings for a proteolytic-rich environment.

    PubMed

    Vasconcelos, Andreia; Cavaco-Paulo, Artur

    2011-04-01

    Wound dressings have experienced continuous and significant changes over the years based on the knowledge of the biochemical events associated with chronic wounds. The development goes from natural materials used to just cover and conceal the wound to interactive materials that can facilitate the healing process, addressing specific issues in non-healing wounds. These new types of dressings often relate with the proteolytic wound environment and the bacteria load to enhance the healing. Recently, the wound dressing research is focusing on the replacement of synthetic polymers by natural protein materials to delivery bioactive agents to the wounds. This article provides an overview on the novel protein-based wound dressings such as silk fibroin keratin and elastin. The improved properties of these dressings, like the release of antibiotics and growth factors, are discussed. The different types of wounds and the effective parameters of healing process will be reviewed.

  18. A Dressing Solution for Burn Wounds: Antibacterial and Low-Adherent Wound Dressings

    NASA Astrophysics Data System (ADS)

    Pu, Tianyun

    Considering the infection and second trauma caused by dressing changes, development of antibacterial and low-adherent wound dressings is urgently needed. Silver ion is a widely used antimicrobial agent, but its cytotoxicity remains a problem. In this study, low-adherent PAM (polyacrylamide) hydrogel incorporated with less toxic AgNP (silver nanoparticle), was immobilized onto PET (poly(ethylene terephthalate)) substrates by an IPN (interpenetrating polymer network) method. The modified PET is effectively antibacterial and the surface is significantly less adherent than untreated PET. However, silver-resistant bacteria become a potential problem. Thus, ionic 5,5-dimethylhydantoin (DMH) analogues containing either a quaternary ammonium moiety or a phosphonate functional group were designed and synthesized. The DMH analogues were converted to antibacterial N-chloramine counterparts through chlorination to serve as potential alternatives to AgNP. The N-chloramine with a structural cation exhibited distinctly enhanced antibacterial functions both in solution and after immobilization on fabrics.

  19. An observational evaluation of a new foam adhesive dressing.

    PubMed

    Merlin-Manton, Elizabeth; Greenwood, Michelle; Linthwaite, Adele

    Following the work of Winter demonstrating the benefits of moist wound healing, there has been a constant stream of wound care products launched into the market to support this concept. This article will describe the findings of an observational evaluation to observe, document and analyse the clinical effectiveness of a new foam adhesive dressing, UrgoTul® Absorb Border (Urgo Medical). The main objective of the evaluation was to define the parameters to allow data capture that would demonstrate the clinical effectiveness of the dressing. Parameters studied and analysed included atraumatic pain-free dressing changes; ease of dressing application; comfort and conformability; exudate management; ability of the dressing to stay in place; and peri-wound skin management. A total of 25 patients with wounds suitable to be dressed using the evaluation product were recruited following a full documented wound assessment by the tissue viability nurse. Participants were selected across the organisation from acute hospital wards and outpatient departments, care homes, wound care clinics and the participants' own homes. Digital photography was used to demonstrate improvement or deterioration of the wound bed and surrounding skin, and images were assessed by non-participating clinicians to confirm documented observations made within the evaluation. The dressing was found to be clinically effective in both chronic and acute wound types, and had an excellent level of participant acceptance. PMID:26266560

  20. An observational evaluation of a new foam adhesive dressing.

    PubMed

    Merlin-Manton, Elizabeth; Greenwood, Michelle; Linthwaite, Adele

    Following the work of Winter demonstrating the benefits of moist wound healing, there has been a constant stream of wound care products launched into the market to support this concept. This article will describe the findings of an observational evaluation to observe, document and analyse the clinical effectiveness of a new foam adhesive dressing, UrgoTul® Absorb Border (Urgo Medical). The main objective of the evaluation was to define the parameters to allow data capture that would demonstrate the clinical effectiveness of the dressing. Parameters studied and analysed included atraumatic pain-free dressing changes; ease of dressing application; comfort and conformability; exudate management; ability of the dressing to stay in place; and peri-wound skin management. A total of 25 patients with wounds suitable to be dressed using the evaluation product were recruited following a full documented wound assessment by the tissue viability nurse. Participants were selected across the organisation from acute hospital wards and outpatient departments, care homes, wound care clinics and the participants' own homes. Digital photography was used to demonstrate improvement or deterioration of the wound bed and surrounding skin, and images were assessed by non-participating clinicians to confirm documented observations made within the evaluation. The dressing was found to be clinically effective in both chronic and acute wound types, and had an excellent level of participant acceptance.

  1. Effects of wound dressings on cultured primary keratinocytes.

    PubMed

    Esteban-Vives, Roger; Young, Matthew T; Ziembicki, Jenny; Corcos, Alain; Gerlach, Jörg C

    2016-02-01

    Autologous cell-spray grafting of non-cultured epidermal cells is an innovative approach for the treatment of severe second-degree burns. After treatment, wounds are covered with dressings that are widely used in wound care management; however, little is known about the effects of wound dressings on individually isolated cells. The sprayed cells have to actively attach, spread, proliferate, and migrate in the wound for successful re-epithelialization, during the healing process. It is expected that exposure to wound dressing material might interfere with cell survival, attachment, and expansion. Two experiments were performed to determine whether some dressing materials have a negative impact during the early phases of wound healing. In one experiment, freshly isolated cells were seeded and cultured for one week in combination with eight different wound dressings used during burn care. Cells, which were seeded and cultured with samples of Adaptic(®), Xeroform(®), EZ Derm(®), and Mepilex(®) did not attach, nor did they survive during the first week. Mepitel(®), N-Terface(®), Polyskin(®), and Biobrane(®) dressing samples had no negative effect on cell attachment and cell growth when compared to the controls. In a second experiment, the same dressings were exposed to pre-cultured cells in order to exclude the effects of attachment and spreading. The results confirm the above findings. This study could be of interest for establishing skin cell grafting therapies in burn medicine and also for wound care in general.

  2. Inductively guided circuits for ultracold dressed atoms

    NASA Astrophysics Data System (ADS)

    Sinuco-León, German A.; Burrows, Kathryn A.; Arnold, Aidan S.; Garraway, Barry M.

    2014-10-01

    Recent progress in optics, atomic physics and material science has paved the way to study quantum effects in ultracold atomic alkali gases confined to non-trivial geometries. Multiply connected traps for cold atoms can be prepared by combining inhomogeneous distributions of DC and radio-frequency electromagnetic fields with optical fields that require complex systems for frequency control and stabilization. Here we propose a flexible and robust scheme that creates closed quasi-one-dimensional guides for ultracold atoms through the ‘dressing’ of hyperfine sublevels of the atomic ground state, where the dressing field is spatially modulated by inductive effects over a micro-engineered conducting loop. Remarkably, for commonly used atomic species (for example, 7Li and 87Rb), the guide operation relies entirely on controlling static and low-frequency fields in the regimes of radio-frequency and microwave frequencies. This novel trapping scheme can be implemented with current technology for micro-fabrication and electronic control.

  3. Supersymmetry in Rydberg-dressed lattice fermions

    NASA Astrophysics Data System (ADS)

    Weimer, Hendrik; Huijse, Liza; Gorshkov, Alexey; Pupillo, Guido; Zoller, Peter; Lukin, Mikhail; Demler, Eugene

    2012-06-01

    Supersymmetry is a powerful tool that allows the characterization of strongly correlated many-body systems, in particular in the case of supersymmetric extensions of the fermionic Hubbard model [1]. At the same time, these models can exhibit rich and exotic physics on their own, such as flat bands with a vanishing dispersion relation. We show that such lattice models can be realized with Rydberg-dressed fermions in optical lattices. Strong interactions within the ground state manifold of the atoms can be realized by admixing a weak contribution of a highly excited Rydberg state [2]. We discuss the unique possbilities of ultracold atoms for the detection of supersymmetry and the effects of tuning the system away from the supersymmetric point.[4pt] [1] P. Fendley, K. Schoutens, J. de Boer, PRL 90, 120402 (2003).[0pt] [2] J. Honer, H. Weimer, T. Pfau, H. P. B"uchler, PRL 105, 160404 (2010).

  4. Toxicity assessment of nanosilver wound dressing in Wistar rat.

    PubMed

    Bidgoli, Sepideh Arbabi; Mahdavi, Moujan; Rezayat, Seyed Mahdi; Korani, Mitra; Amani, Amir; Ziarati, Parisa

    2013-05-07

    Antibiotic resistance to microorganisms is one of the major problems faced in the field of wound care in burns patients. Silver nanoparticles have come up as potent antimicrobial agent and are being evaluated in diverse medical applications ranging from silver based dressings to silver coated medical devices. We aimed in present study to test the release of nanosilver from nanosilver wound dressing and compare the dermal and systemic toxicity of nanosilver dressings in a repeated dose (21 days) model. Under general anesthesia, a limited standard 2nd degree burns were provided on the back of each rat in all treatment, negative control (simple dressing) and 5% silver nitrate groups, each contained 5 male wistar rats. According to the analysis made by atomic absorption spectrometry, the wound dressings released 0.599 ± 0.083 ppm of nanosilver during first 24 hrs of study. Daily observations were recoded and wounds were covered with new dressings each 24 hrs. Burn healing was observed in nanosilver wound dressing group in shorter time periods than the control groups. In toxicity assessment, this dressing didn't cause any hematological and histopathological abnormalities in treatment group but biochemical studies showed significant rise of plasma transaminase (ALT) at the endpoint (21 days) of the study (P=0.027). Portal mononuclear lymphoid and polymorphonuclear leukocyte infiltrations in three to four adjacent foci were recognized around the central hepatic vein in treatment group. Mild hepatotoxic effects of nanosilver wound dressing in wistar rat emphasize the necessity of more studies on toxicity potentials of low dose nanosilver by dermal applications.

  5. Conservative management of exomphalos major with silver dressings: are they safe?

    PubMed

    Lewis, Nicola; Kolimarala, Vinod; Lander, Anthony

    2010-12-01

    Historically, some dressings used in exomphalos major were associated with toxicity. These have been abandoned in favor of safer dressings. Silver toxicity has not been described following the use of silver dressings in infants. We, however, found disconcerting serum silver levels in 2 consecutive patients during treatment with silver salt containing dressings.

  6. Dressed spin of polarized {sup 3}He in a cell

    SciTech Connect

    Chu, P.-H.; Esler, A. M.; Peng, J. C.; Beck, D. H.; Chandler, D. E.; Clayton, S.; Williamson, S.; Yoder, J.; Hu, B.-Z.; Ngan, S. Y.; Sham, C. H.; So, L. H.

    2011-08-15

    We report a measurement of the modification of the effective precession frequency of polarized {sup 3}He atoms in response to a dressing field in a room-temperature cell. The {sup 3}He atoms were polarized using the metastability spin-exchange method. An oscillating dressing field was then applied perpendicular to the constant magnetic field. Modification of the {sup 3}He effective precession frequency was observed over a broad range of the amplitude and frequency of the dressing field. The observed effects are compared with calculations based on quantum optics formalism.

  7. Scanning electron microscopy of biosynthetic wound dressings Biocol.

    PubMed

    Pogorelov, A G; Gavriluk, V B; Pogorelova, V N; Gavriluk, B K

    2012-11-01

    The surface of wound dressing Biocol was studied by scanning electron microscopy. This composite system consists of latex matrix with incorporated water-soluble polysaccharide. The peculiarities of the surface are important for manufacturing of the dressing and for modification of its surface upon contact with fluids, e.g. during de novo tissue reconstruction. The method for studying the fine structure of the polymeric film surface was developed. The relief of the wound dressing changes during interaction with the fluid and nanopores appear on the surface. Thus, scanning electron microscopy is an informative method for studying the surface of biosynthetic films. PMID:23330116

  8. Triple-mode squeezing with dressed six-wave mixing.

    PubMed

    Wen, Feng; Li, Zepei; Zhang, Yiqi; Gao, Hong; Che, Junling; Che, Junling; Abdulkhaleq, Hasan; Zhang, Yanpeng; Wang, Hongxing

    2016-05-12

    The theory of proof-of-principle triple-mode squeezing is proposed via spontaneous parametric six-wave mixing process in an atomic-cavity coupled system. Special attention is focused on the role of dressed state and nonlinear gain on triple-mode squeezing process. Using the dressed state theory, we find that optical squeezing and Autler-Towns splitting of cavity mode can be realized with nonlinear gain, while the efficiency and the location of maximum squeezing point can be effectively shaped by dressed state in atomic ensemble. Our proposal can find applications in multi-channel communication and multi-channel quantum imaging.

  9. Dressed solitons in quantum electron-positron-ion plasmas

    NASA Astrophysics Data System (ADS)

    Chatterjee, Prasanta; Roy, Kaushik; Mondal, Ganesh; Muniandy, S. V.; Yap, S. L.; Wong, C. S.

    2009-12-01

    Nonlinear propagation of quantum ion acoustic waves in a dense quantum plasma whose constituents are electrons, positrons, and positive ions is investigated using a quantum hydrodynamic model. The Korteweg-de Vries equation is derived using reductive perturbation technique. The higher order inhomogeneous differential equation is obtained for the dressed soliton. The dynamical equation for dressed soliton is solved using the renormalization method. The conditions for the validity of the higher order correction are described. The effects of quantum parameter, positron concentration, electron to positron Fermi temperature ratio, and soliton velocity on the amplitude and width of the dressed soliton are studied.

  10. Triple-mode squeezing with dressed six-wave mixing

    PubMed Central

    Wen, Feng; Li, Zepei; Zhang, Yiqi; Gao, Hong; Che, Junling; Che, Junling; Abdulkhaleq, Hasan; Zhang, Yanpeng; Wang, Hongxing

    2016-01-01

    The theory of proof-of-principle triple-mode squeezing is proposed via spontaneous parametric six-wave mixing process in an atomic-cavity coupled system. Special attention is focused on the role of dressed state and nonlinear gain on triple-mode squeezing process. Using the dressed state theory, we find that optical squeezing and Autler-Towns splitting of cavity mode can be realized with nonlinear gain, while the efficiency and the location of maximum squeezing point can be effectively shaped by dressed state in atomic ensemble. Our proposal can find applications in multi-channel communication and multi-channel quantum imaging. PMID:27169878

  11. Adiabatic control of atomic dressed states for transport and sensing

    NASA Astrophysics Data System (ADS)

    Cooper, N. R.; Rey, A. M.

    2015-08-01

    We describe forms of adiabatic transport that arise for dressed-state atoms in optical lattices. Focusing on the limit of weak tunnel-coupling between nearest-neighbor lattice sites, we explain how adiabatic variation of optical dressing allows control of atomic motion between lattice sites: allowing adiabatic particle transport in a direction that depends on the internal state, and force measurements via spectroscopic preparation and readout. For uniformly filled bands these systems display topologically quantized particle transport. An implementation of the dressing scheme using optical transitions in alkaline-earth atoms is discussed as well as its favorable features for precise force sensing.

  12. [Care of the non-tunneled central venous catheter. Literature search on disinfectants, dressings and intervals between dressing changes].

    PubMed

    Ausserhofer, Dietmar; Fritz, Elfriede; Them, Christa

    2008-08-01

    Patient care in hospitals often involves insertion of a non-tunneled central venous catheter for administering drugs, intravenous solutions, or total parenteral nutrition. Every change of dressing must be carried out in an appropriate fashion in order to reduce the risk of bacterial infection. We reviewed the existent literature in order to make a listof recommended disinfectants, type of dressings and intervals between dressing changes of a central venous catheter. A comparison was drawn between the guidelines of the Centers for Disease Control and Prevention (CDC) and the Robert Koch-Institut (RKI) issued in 2002 with those more recently published. Our search showed that chlorhexidine gluconate (from 0.5 to 2 percent), povidone-iodine (from 5 to 10 percent) or alcohol (70 percent) are the recommended disinfecting agents. The recommended dressing is gauze or transparent steam-permeable polyurethane dressings. Intervals between dressing changes varied between once a day and once in seven days, depending on the nature of the dressing applied.

  13. DRESS syndrome with autoimmune hepatitis from strontium ranelate.

    PubMed

    di Meo, Nicola; Gubertini, Nicoletta; Crocè, Lory; Tiribelli, Claudio; Trevisan, Giusto

    2016-05-01

    Strontium ranelate, which is used for postmenopausal osteoporosis, has been associated with drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, a severe, acute, potentially fatal, multisystem adverse drug reaction characterized by skin rash, fever, hematological abnormalities, and lymphadenopathy with involvement of several internal organs. We report the case of a woman who developed DRESS syndrome with a generalized maculopapular rash, eosinophilia, dyspnea, bilateral cervical lymphadenopathy, and reactivation of Epstein-Barr virus (EBV) with liver damage 3 weeks after administration of strontium ranelate for postmenopausal osteoporosis. Approximately 6 months after total remission of cutaneous symptoms, the patient developed autoimmune hepatitis. This case confirms that strontium ranelate should be considered as a possible factor in the etiopathology of DRESS syndrome as well as in the subsequent development of autoimmune hepatitis. The possibility of developing autoimmune hepatitis as a part of DRESS syndrome related to strontium ranelate use can occur months after the acute episode. PMID:27274555

  14. 9. View to west of Tropic Dressing Room (typical). ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. View to west of Tropic Dressing Room (typical). - Natick Research & Development Laboratories, Climatic Chambers Building, U.S. Army Natick Research, Development & Engineering Center (NRDEC), Natick, Middlesex County, MA

  15. Seed dressings to control slug damage in oilseed rape.

    PubMed

    Simms, Louise C; Mullins, Christopher E; Wilson, Michael J

    2002-07-01

    Slugs are major pests of oilseed rape that are poorly controlled by conventional bait pellets. A series of laboratory experiments investigated the potential of seed-dressings to control slug damage in this crop. Four compounds: metaldehyde, methiocarb, cinnamamide and 3,5-dimethoxycinnamic acid (DMCA) were tested at a range of doses for phytotoxicity and ability to reduce damage by Deroceras reticulatum (Müller). Metaldehyde and methiocarb were not phytotoxic at any doses, whereas all doses of cinnamamide and DMCA were. All compounds reduced slug damage, but metaldehyde and methiocarb consistently performed better than cinnamamide and DMCA. Metaldehyde and methiocarb seed-dressings were compared with baited pellets containing the same active ingredients at recommended field doses. The seed-dressings protected plants from damage by D reticulatum and Arion subfuscus (Draparnaud) as well as, or better than, baited pellets. We therefore recommend that metaldehyde and methiocarb should be field-tested as seed dressings to control slugs in oilseed rape.

  16. 12. VIEW, LOOKING SOUTH FROM LEFT TO RIGHT, SHOWING DRESSING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. VIEW, LOOKING SOUTH FROM LEFT TO RIGHT, SHOWING DRESSING FROM AND WORK/CHAMBER ROOM - U.S. Naval Submarine Base, New London Submarine Escape Training Tank, Albacore & Darter Roads, Groton, New London County, CT

  17. 3. INTERIOR VIEW OF PARTITIONS IN DRESSING ROOM; INTERIOR HALLWAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. INTERIOR VIEW OF PARTITIONS IN DRESSING ROOM; INTERIOR HALLWAY FOR HYDROTHERAPY AREA AT RIGHT - Fort McCoy, Building No. T-1054, South side of South Tenth Avenue, Block 10, Sparta, Monroe County, WI

  18. [Design of a Special Shaped Foam Dressing Based on Anatomy].

    PubMed

    Shen, Yunming; Wang, Lin; Zheng, Siyu; Zhang, Keping; Zheng, Kun

    2015-07-01

    As the dressings currently used in clinic settings unflat shape in general, they can't be fitted completely on occiput, heel, elbow, knee and other body parts unflat. This paper developed one kind of foam dressing of special shape based on local anatomy. The foam dressing is waterproof and air permeable, it can cover the wound closely enough to prevent bacteria from invasion and infection. With a saturated absorption ratio of 1: 8 or higher, it can keep the wound clean and moisture by absorbing large amounts of wound inflammatory secretions and is almost completely permeable to oxygen and carbon dioxide. Assuring safety and effect meanwhile, it has better outcomes than common dressings in the same application settings. PMID:26665946

  19. [THE ROLE OF WOUND DRESSING IN BIOFILM DESTRUCTION AND REFORMATION].

    PubMed

    Tunuković, Suzana

    2016-03-01

    Application of supportive wound dressing is an important segment for successful result of modern treatment of chronic ulcers. The right choice of dressing is the key to faster, better, and ultimately more cost-effective treatment outcome. Due to the extremely large number of generic types and variants, the main element for proper dressing selection is to know the mechanisms of action and clinical evidence of the effectiveness because of many local factors that delay ulcer healing. The advent of wound dressing that is efficient at the three clinically identified key local factors that largely impede the healing of ulcers, i.e. exudate, infection and biofilm, has made a significant step forward in the creation of optimal conditions for faster healing of chronic ulcers. The complexity of the effects of new technologies, which integrate hidrofiber technology and Ag + technology, provides effective antimicrobial control while at the same time preventing biofilm reformation.

  20. 9. VIEW OF SOUTHERN ROCKFACED DRESSED AND MORTARED STONE ABUTMENT, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. VIEW OF SOUTHERN ROCKFACED DRESSED AND MORTARED STONE ABUTMENT, SHOWING STEEL CROSSBEAMS, TORSIONAL DIAGONAL STRUTS, AND WOODEN STRINGERS. FACING SOUTHWEST. - Coverts Crossing Bridge, Spanning Mahoning River along Township Route 372 (Covert Road), New Castle, Lawrence County, PA

  1. DEVELOPMENT OF A NEXT-GENERATION ANTIMICROBIAL WOUND DRESSING.

    PubMed

    Metcalf, Daniel; Parsons, David; Bowler, I Philip

    2016-03-01

    Delayed wound healing due to infection is a burden on healthcare systems, and the patient and caregiver alike. An emerging factor in infection and delayed healing is the presence development of biofilm in wounds. Biofilm is communities of microorganisms, protected by an extracellular matrix of slime in the wound, which can tolerate host defences and applied antimicrobials such as antibiotics or antimicrobial dressings. A growing evidence base exists suggesting that biofilm exists in a majority of chronic wounds, and can be a precursor to infection while causing delayed healing itself. In vivo models have demonstrated that the inflammatory, granulation and epithelialization processes of normal wound healing are impaired by biofilm presence. The challenge in the development of a new antimicrobial wound dressing was to make standard antimicrobial agents more effective against biofilm, and this was answered following extensive biofilm research and testing. A combination of metal chelator, surfactant and pH control displayed highly synergistic anti-biofilm action with 1.2% ionic silver in a carboxymethylcellulose dressing. Its effectiveness was challenged and proven in complex in vitro and in vivo wound biofilm models, followed by clinical safety and performance demonstrations in a 42-patient study and 113 clinical evaluations. Post-market surveillance was conducted on the commercially available dressing, and in a 112-case evaluation, the dressing was shown to effectively manage exudate and suspected biofilm while shifting difficult-to-heal wounds onto healing trajectories, after an average of 4 weeks of new dressing use in otherwise standard wound care protocols. This was accompanied by a low frequency of dressing related adverse events. In a second evaluation, clinical signs of infection and wound dimension data, before and after the evaluations, were also available. Following an average of 5.4 weeks of dressing use, all signs of clinical infection were reduced, from

  2. DEVELOPMENT OF A NEXT-GENERATION ANTIMICROBIAL WOUND DRESSING.

    PubMed

    Metcalf, Daniel; Parsons, David; Bowler, I Philip

    2016-03-01

    Delayed wound healing due to infection is a burden on healthcare systems, and the patient and caregiver alike. An emerging factor in infection and delayed healing is the presence development of biofilm in wounds. Biofilm is communities of microorganisms, protected by an extracellular matrix of slime in the wound, which can tolerate host defences and applied antimicrobials such as antibiotics or antimicrobial dressings. A growing evidence base exists suggesting that biofilm exists in a majority of chronic wounds, and can be a precursor to infection while causing delayed healing itself. In vivo models have demonstrated that the inflammatory, granulation and epithelialization processes of normal wound healing are impaired by biofilm presence. The challenge in the development of a new antimicrobial wound dressing was to make standard antimicrobial agents more effective against biofilm, and this was answered following extensive biofilm research and testing. A combination of metal chelator, surfactant and pH control displayed highly synergistic anti-biofilm action with 1.2% ionic silver in a carboxymethylcellulose dressing. Its effectiveness was challenged and proven in complex in vitro and in vivo wound biofilm models, followed by clinical safety and performance demonstrations in a 42-patient study and 113 clinical evaluations. Post-market surveillance was conducted on the commercially available dressing, and in a 112-case evaluation, the dressing was shown to effectively manage exudate and suspected biofilm while shifting difficult-to-heal wounds onto healing trajectories, after an average of 4 weeks of new dressing use in otherwise standard wound care protocols. This was accompanied by a low frequency of dressing related adverse events. In a second evaluation, clinical signs of infection and wound dimension data, before and after the evaluations, were also available. Following an average of 5.4 weeks of dressing use, all signs of clinical infection were reduced, from

  3. [DRESS in intensive care unit: a challenging diagnosis and treatment].

    PubMed

    Derlon, V; Audibert, G; Barbaud, A; Mertes, P M

    2014-12-01

    Drug reaction with eosinophilia ans systemic symptoms (DRESS) is a severe medication-induced adverse reaction, which can threaten patient's life. Clinical symptoms and organ failures present wide variability. Furthermore, the latency period is long, so that diagnosis could be a real challenge in the intensive care unit. We report the case of a woman developing a DRESS after neurosurgery complicated by a nosocomial infection. PMID:25450727

  4. 5. GENERAL VIEW OF HOG DRESSING AREA ON LEVEL 4; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. GENERAL VIEW OF HOG DRESSING AREA ON LEVEL 4; LOOKING WEST; WORKERS STOOD ON RAISED PLATFORMS TO EVISCERATE AND WASH CARCASSES; EXPANDED STEEL GRATING PROVIDED NON-SLIP WORKING SURFACE; STAINLESS-STEEL BAFFLES BETWEEN PLATFORMS HELPED TO CONTAIN STEAM AND WATER SPRAY; METAL TROUGHS BELOW PLATFORMS AND CONCRETE GUTTERS IN FLOOR HELPED CHANNEL WASTE WATER TO DRAINS - Rath Packing Company, Hog Dressing Building, Sycamore Street between Elm & Eighteenth Streets, Waterloo, Black Hawk County, IA

  5. Dressed soliton in quantum dusty pair-ion plasma

    SciTech Connect

    Chatterjee, Prasanta; Muniandy, S. V.; Wong, C. S.; Roy, Kaushik

    2009-11-15

    Nonlinear propagation of a quantum ion-acoustic dressed soliton is studied in a dusty pair-ion plasma. The Korteweg-de Vries (KdV) equation is derived using reductive perturbation technique. A higher order inhomogeneous differential equation is obtained for the higher order correction. The expression for a dressed soliton is calculated using a renormalization method. The expressions for higher order correction are determined using a series solution technique developed by Chatterjee et al. [Phys. Plasmas 16, 072102 (2009)].

  6. An overview of Acticoat dressing in wound management.

    PubMed

    Dowsett, Caroline

    2003-10-01

    This article reviews the in vitro and in vivo studies available on a new nanocrystalline silver dressing, Acticoat (Smith & Nephew), and discusses their relevance to the availability of this product on the Drug Tariff. The addition of nanocrystalline silver dressings will make a valuable contribution to wound care in the community, in terms of providing continuity of care for patients who are discharged from hospital and also in preventing admission to hospital with non-manageable wound infection.

  7. Application of wound dressings in dermatology laser procedures

    NASA Astrophysics Data System (ADS)

    Hetzel, Fred W.; Chen, Qun; Hoskins, Greg

    1995-05-01

    High powered lasers have been used in dermatological procedures such as tattoo removal. This use is associated with a potential, biological hazard of high speed tissue particles from the laser field. It has been proposed that by applying a clear dermatological would dressing directly over the laser treatment site, it may be possible to completely trap the potentially airborne tissue particles from the procedure. Some important questions must be addressed prior to the implementation of such a technique. While the use of a wound dressing may significantly reduce the airborne materials during the laser procedures, new problems may arise: 1 . The wound dressing or some of its components may absorb excessive amount of light energy. This would result in a very localized temperature rise which may be harmful to the patient; 2. The smooth surface of the wound dressing material could induce specular reflection of the incident laser beam, thus introducing a laser hazard to the staff and patient. To address these possible problems, we studied a series of ClearSite Wound Dressings which have been reportedly tested for such laser procedures. The objective of the studies were, to determine if the use of ClearSite in conjunction with laser procedures poses a possible hazard to either the patient or to the Operating Room personnel, and to determine the effect of the ClearSite dressing on the optical characteristics of the light beam. The latter includes light absorption and transmittance for various wavelengths.

  8. Biomedical evaluation of a novel nitrogen oxides releasing wound dressing.

    PubMed

    Dave, Rachna N; Joshi, Hiren M; Venugopalan, Vayalam P

    2012-12-01

    Chronic wounds are a major cause for both suffering and economical losses. Management of chronic non-healing wounds requires multipronged approach. They are polymicrobial and agonizing for the patient due to associated pain. Moist dressing providing antimicrobial action is a highly desirable chronic wound management option. Here we report a hydrogel based dressing that possesses the antimicrobial properties of acidified sodium nitrite and the homeostatic property of a hydrogel. The dressing was developed by combining citric acid cross-linked cotton gauze and sodium nitrite loaded gelatin. The cotton gauze was cross-linked with citric acid by pad-dry-curing in presence of nano-titania catalyst. The cotton gauze-gelatin hydrogel combination was gamma-irradiated and freeze-dried. At the time of application, the freeze-dried dressing is wetted by sodium nitrite solution. The dressing has a fluid uptake ability of 90 % (w/v) and the water vapour evaporation rate was estimated to be 2,809 ± 20 g/m(2)/day. The dressing showed significant antimicrobial activity against both planktonic and biofilm forms and was effective during consecutive re-uses. Cytotoxicity study showed inhibition of fibroblasts, but to a lesser extent than clinically administered concentrations of antiseptic like povidone iodine. Storage at 37 °C over a 3 month period resulted in no significant loss of its antimicrobial activity.

  9. Evaluation of a new liquid occlusive dressing for excisional wounds.

    PubMed

    Singer, Adam J; Nable, Maria; Cameau, Paul; Singer, Daniel D; McClain, Steve A

    2003-01-01

    We evaluated a novel octylcyanoacrylate-based liquid occlusive dressing for partial-thickness wounds. One hundred and fifteen standardized wounds were created with an electric dermatome set at a depth of 600 micro on the flanks of three pigs and randomly treated with liquid occlusive dressing, a hydrocolloid dressing, or gauze. In one pig, wounds were swabbed with Staphylococcus aureus. Biopsies were taken after 4, 5, 6, and 21 days. Hemostasis was obtained in all wounds treated with the liquid occlusive. The percent reepithelialization of wounds treated with the liquid occlusive and hydrocolloid dressings were significantly greater at days 4 and 5 than control wounds (78% and 82% vs. 40%, p < 0.001 and 99% and 100% vs. 72%, p < 0.001, respectively). None of the liquid occlusive-treated wounds challenged with bacteria became infected. Foreign body reactions were least common in wounds treated with the liquid occlusive (p < 0.001). Scar depth was less for liquid occlusive- and hydrocolloid-treated wounds than controls (285 micro and 303 micro vs. 490 micro, p < 0.001). We conclude that excisional wounds treated with the liquid occlusive dressing reepithelialize as quickly as hydrocolloid-treated wounds. The liquid occlusive dressing is an effective microbial barrier and hemostatic agent resulting in fewer foreign body reactions than hydrocolloid-treated wounds or controls.

  10. The brain's dress code: How The Dress allows to decode the neuronal pathway of an optical illusion.

    PubMed

    Schlaffke, Lara; Golisch, Anne; Haag, Lauren M; Lenz, Melanie; Heba, Stefanie; Lissek, Silke; Schmidt-Wilcke, Tobias; Eysel, Ulf T; Tegenthoff, Martin

    2015-12-01

    Optical illusions have broadened our understanding of the brain's role in visual perception. A modern day optical illusion emerged from a posted photo of a striped dress, which some perceived as white and gold and others as blue and black. Here we show, using functional magnetic resonance imaging (fMRI), that those who perceive The Dress as white/gold have higher activation in response to the image of The Dress in brain regions critically involved in higher cognition (frontal and parietal brain areas). These results are consistent with theories of top-down modulation and present a neural signature associated with the differences in perceiving The Dress as white/gold or blue/black. Furthermore the results support recent psychophysiological data on this phenomenon and provide a fundamental building block to study interindividual differences in visual processing. PMID:26478963

  11. Inductively guided circuits for ultracold dressed atoms

    PubMed Central

    Sinuco-León, German A.; Burrows, Kathryn A.; Arnold, Aidan S.; Garraway, Barry M.

    2014-01-01

    Recent progress in optics, atomic physics and material science has paved the way to study quantum effects in ultracold atomic alkali gases confined to non-trivial geometries. Multiply connected traps for cold atoms can be prepared by combining inhomogeneous distributions of DC and radio-frequency electromagnetic fields with optical fields that require complex systems for frequency control and stabilization. Here we propose a flexible and robust scheme that creates closed quasi-one-dimensional guides for ultracold atoms through the ‘dressing’ of hyperfine sublevels of the atomic ground state, where the dressing field is spatially modulated by inductive effects over a micro-engineered conducting loop. Remarkably, for commonly used atomic species (for example, 7Li and 87Rb), the guide operation relies entirely on controlling static and low-frequency fields in the regimes of radio-frequency and microwave frequencies. This novel trapping scheme can be implemented with current technology for micro-fabrication and electronic control. PMID:25348163

  12. Effects of wound dressings on cultured primary keratinocytes.

    PubMed

    Esteban-Vives, Roger; Young, Matthew T; Ziembicki, Jenny; Corcos, Alain; Gerlach, Jörg C

    2016-02-01

    Autologous cell-spray grafting of non-cultured epidermal cells is an innovative approach for the treatment of severe second-degree burns. After treatment, wounds are covered with dressings that are widely used in wound care management; however, little is known about the effects of wound dressings on individually isolated cells. The sprayed cells have to actively attach, spread, proliferate, and migrate in the wound for successful re-epithelialization, during the healing process. It is expected that exposure to wound dressing material might interfere with cell survival, attachment, and expansion. Two experiments were performed to determine whether some dressing materials have a negative impact during the early phases of wound healing. In one experiment, freshly isolated cells were seeded and cultured for one week in combination with eight different wound dressings used during burn care. Cells, which were seeded and cultured with samples of Adaptic(®), Xeroform(®), EZ Derm(®), and Mepilex(®) did not attach, nor did they survive during the first week. Mepitel(®), N-Terface(®), Polyskin(®), and Biobrane(®) dressing samples had no negative effect on cell attachment and cell growth when compared to the controls. In a second experiment, the same dressings were exposed to pre-cultured cells in order to exclude the effects of attachment and spreading. The results confirm the above findings. This study could be of interest for establishing skin cell grafting therapies in burn medicine and also for wound care in general. PMID:26678326

  13. Biofilm hydrogel dressing: a clinical evaluation in the treatment of pressure sores.

    PubMed

    Darkovich, S L; Brown-Etris, M; Spencer, M

    1990-01-01

    A new dressing for chronic wounds, BioFilm hydrogel dressing, was compared to a hydrocolloid dressing (HCD) control in a clinical trial involving 90 patients and 129 Stage I and II wounds (defined by Enis and Sarmienti). The testing sites included both acute care and extended care facilities. A comparison of healing response and functional characteristics of both dressings was part of this assessment. Biofilm dressings demonstrated a healing advantage over the HCD. In addition, clinicians judged that the hydrogel dressings were easier to use and had superior fluid management capability and product integrity with minimal disruption to the healing wounds.

  14. Groin dressing after cardiac catheterization. Comparison between light dressing with thin transparent tape (Tegaderm) and conventional tight/pressure dressing with an elastic adhesive bandage (Tensoplast).

    PubMed

    Boonbaichaiyapruck, S; Hutayanon, P; Chanthanamatta, P; Dumrongwatana, T; Intarayotha, N; Krisdee, V; Yamvong, S

    2001-12-01

    Post cardiac catheterization puncture site care is usually done with a tight pressure dressing by an elastic adhesive bandage (Tensoplast) due to the belief that it should prevent bleeding. The practice is uncomfortable to the patients. The authors compared a new way of dressing using light transparent tape (Tegaderm) to the conventional tight pressure one. 126 post coronary angiography patients were randomized to have their groins dressed either with Tensoplast or with Tegaderm. Patients ambulated 8 hours after the procedures. The groin was evaluated for pain, discomfort and bleeding complications. 49 per cent in the Tensoplast vs 26.9 per cent in the Tegaderm group experienced pain (p value of 0.01). 55.5 per cent in the Tensoplast group vs 11.1 per cent in the Tegaderm group reported discomfort. 4.7 per cent in the Tensoplast vs 1.6 per cent in the Tegaderm group developed bleeding or hematoma. Dressing of the puncture site after cardiac catheterization with Tegaderm was more comfortable than the conventional Tensoplast without any difference in bleeding complications.

  15. Application of VitaVallis dressing for infected wounds

    SciTech Connect

    Kirilova, N. V. Fomenko, A. N. Korovin, M. S.

    2015-11-17

    Today there is a growing demand for safe and efficient antimicrobial dressings for infected wound treatment. The antimicrobial sorption material for VitaVallis dressings was produced by one-stage oxidation of aluminum nanopowder in water in the presence of fibrous acetylcellulose matrix. Scanning electron microscopy revealed that the material is made up of fibers of diameter 1.5–3.0 µm with adhered agglomerated alumina nanosheets. An antimicrobial study revealed a high inhibitory effect of VitaVallis against the growth of gram-negative (E.coli, P. aeruginosa) and gram-positive (S. aureus) strains. The antimicrobial activity of the dressing against microbial pathogens on the wound surface was demonstrated in in vivo experiments on male rats. The dressing was also tested on volunteer patients. The testing showed reduction of the wound healing period, accelerated cleaning of the infected wound and enhanced tissue regeneration in the wound. The results demonstrate that the VitaVallis dressing can be used for the treatment of deep infected wounds.

  16. Advanced Therapeutic Dressings for Effective Wound Healing--A Review.

    PubMed

    Boateng, Joshua; Catanzano, Ovidio

    2015-11-01

    Advanced therapeutic dressings that take active part in wound healing to achieve rapid and complete healing of chronic wounds is of current research interest. There is a desire for novel strategies to achieve expeditious wound healing because of the enormous financial burden worldwide. This paper reviews the current state of wound healing and wound management products, with emphasis on the demand for more advanced forms of wound therapy and some of the current challenges and driving forces behind this demand. The paper reviews information mainly from peer-reviewed literature and other publicly available sources such as the US FDA. A major focus is the treatment of chronic wounds including amputations, diabetic and leg ulcers, pressure sores, and surgical and traumatic wounds (e.g., accidents and burns) where patient immunity is low and the risk of infections and complications are high. The main dressings include medicated moist dressings, tissue-engineered substitutes, biomaterials-based biological dressings, biological and naturally derived dressings, medicated sutures, and various combinations of the above classes. Finally, the review briefly discusses possible prospects of advanced wound healing including some of the emerging physical approaches such as hyperbaric oxygen, negative pressure wound therapy and laser wound healing, in routine clinical care.

  17. Application of VitaVallis dressing for infected wounds

    NASA Astrophysics Data System (ADS)

    Kirilova, N. V.; Fomenko, A. N.; Korovin, M. S.

    2015-11-01

    Today there is a growing demand for safe and efficient antimicrobial dressings for infected wound treatment. The antimicrobial sorption material for VitaVallis dressings was produced by one-stage oxidation of aluminum nanopowder in water in the presence of fibrous acetylcellulose matrix. Scanning electron microscopy revealed that the material is made up of fibers of diameter 1.5-3.0 µm with adhered agglomerated alumina nanosheets. An antimicrobial study revealed a high inhibitory effect of VitaVallis against the growth of gram-negative (E.coli, P. aeruginosa) and gram-positive (S. aureus) strains. The antimicrobial activity of the dressing against microbial pathogens on the wound surface was demonstrated in in vivo experiments on male rats. The dressing was also tested on volunteer patients. The testing showed reduction of the wound healing period, accelerated cleaning of the infected wound and enhanced tissue regeneration in the wound. The results demonstrate that the VitaVallis dressing can be used for the treatment of deep infected wounds.

  18. Chronic Wound Dressings Based on Collagen-Mimetic Proteins

    PubMed Central

    Cereceres, Stacy; Touchet, Tyler; Browning, Mary Beth; Smith, Clayton; Rivera, Jose; Höök, Magnus; Whitfield-Cargile, Canaan; Russell, Brooke; Cosgriff-Hernandez, Elizabeth

    2015-01-01

    Objective: Chronic wounds are projected to reach epidemic proportions due to the aging population and the increasing incidence of diabetes. There is a strong clinical need for an improved wound dressing that can balance wound moisture, promote cell migration and proliferation, and degrade at an appropriate rate to minimize the need for dressing changes. Approach: To this end, we have developed a bioactive, hydrogel microsphere wound dressing that incorporates a collagen-mimetic protein, Scl2GFPGER, to promote active wound healing. A redesigned Scl2GFPGER, engineered collagen (eColGFPGER), was created to reduce steric hindrance of integrin-binding motifs and increase overall stability of the triple helical backbone, thereby resulting in increased cell adhesion to substrates. Results: This study demonstrates the successful modification of the Scl2GFPGER protein to eColGFPGER, which displayed enhanced stability and integrin interactions. Fabrication of hydrogel microspheres provided a matrix with adaptive moisture technology, and degradation rates have potential for use in human wounds. Innovation: This collagen-mimetic wound dressing was designed to permit controlled modulation of cellular interactions and degradation rate without impact on other physical properties. Its fabrication into uniform hydrogel microspheres provides a bioactive dressing that can readily conform to irregular wounds. Conclusion: Overall, this new eColGFPGER shows strong promise in the generation of bioactive hydrogels for wound healing as well as a variety of tissue scaffolds. PMID:26244101

  19. Transient absorption spectra of the laser-dressed hydrogen atom

    NASA Astrophysics Data System (ADS)

    Murakami, Mitsuko; Chu, Shih-I.

    2013-10-01

    We present a theoretical study of transient absorption spectra of laser-dressed hydrogen atoms, based on numerical solutions of the time-dependent Schrödinger equation. The timing of absorption is controlled by the delay between an extreme ultra violet (XUV) pulse and an infrared (IR) laser field. The XUV pulse is isolated and several hundred attoseconds in duration, which acts as a pump to drive the ground-state electron to excited p states. The subsequent interaction with the IR field produces dressed states, which manifest as sidebands between the 1s-np absorption spectra separated by one IR-photon energy. We demonstrate that the population of dressed states is maximized when the timing of the XUV pulse coincides with the zero crossing of the IR field, and that their energies can be manipulated in a subcycle time scale by adding a chirp to the IR field. An alternative perspective to the problem is to think of the XUV pulse as a probe to detect the dynamical ac Stark shifts. Our results indicate that the accidental degeneracy of the hydrogen excited states is removed while they are dressed by the IR field, leading to large ac Stark shifts. Furthermore, we observe the Autler-Townes doublets for the n=2 and 3 levels using the 656 nm dressing field, but their separation does not agree with the prediction by the conventional three-level model that neglects the dynamical ac Stark shifts.

  20. Effect of Hydrofiber wound dressings on bacterial ultrastructure.

    PubMed

    Hobot, Jan; Walker, Michael; Newman, Geoffrey; Bowler, Philip

    2008-04-01

    Ionic silver has well-proven bactericidal properties, and silver-containing wound dressings are now widely used to aid in the creation of an antimicrobial environment in wounds. The effect of silver ions on bacterial ultrastructure can best be studied by viewing bacterial cells under a transmission electron microscope (TEM). Bacterial cells of Pseudomonas aeruginosa were incubated within a control dressing (e.g. a non-antimicrobial Hydrofiber dressing) (Hydrofiber is a registered trademark of E.R. Squibb and Sons, L.L.C.) and a silver-containing Hydrofiber dressing, followed by processing for TEM. Liquid cultures, with and without silver, were prepared for comparison. The addition of silver to growing bacterial cultures stopped growth of the cells very quickly. Ultrastructurally, the presence of silver was found to affect both the shape of the bacterial nucleoid and the organization of bacterial DNA. X-ray microanalysis of bacteria from liquid cultures showed the presence of silver within silver-treated cells and the absence of calcium. It is suggested that the presence of available silver ions within the Hydrofiber dressing could lead to the loss of cellular ions, vital for maintaining the structural integrity of the nuclear area.

  1. Novel wound models for characterizing ibuprofen release from foam dressings.

    PubMed

    Steffansen, Bente; Herping, Sofie P K

    2008-11-19

    The purpose of the present study was to design and characterize low exudate level wound (LEW) and high exudate level wound (HEW) in vitro models by means of investigating therapeutic substance release from exudate-absorbing formulations. Biatain Ibu foam dressing was used to characterize in vitro release of ibuprofen within the models and also for in vitro-in vivo correlation (IVIVC) studies. Ibuprofen release was described by zero order rate constants of 0.0147 for 1 day and 0.0038 mg/cm(2) h for 3 days in HEW and LEW models, respectively. The release is suggested to be controlled by ibuprofen diffusion from the dressing in the HEW model, whereas fluid absorption is rate-limiting in the LEW model. Ibuprofen release, from Biatain Ibu foam dressings in vivo, is within the same ranges as in vitro. Thus, it is suggested that, depending on the level of exudate, the in vivo release of ibuprofen depends on ibuprofen diffusion from and absorption of exudates to the dressings. Consequently, both the HEW and LEW in vitro models should be applied in order to fully characterize ibuprofen release from Biatain Ibu foam dressings. Future studies may show whether these in vitro models can be used to characterize therapeutic substance release from exudate-absorbing formulations in general.

  2. Development of antimicrobial and scar preventive chitosan hydrogel wound dressings.

    PubMed

    Anjum, Sadiya; Arora, Abha; Alam, M S; Gupta, Bhuvanesh

    2016-07-11

    Antimicrobial and scar preventive wound dressings were developed by coating a blend of chitosan (CS), polyethylene glycol (PEG) and polyvinyl pyrolidone (PVP) on the cotton fabric and subsequent freeze drying. The miscibility of blend systems and functional group interaction were investigated by attenuated total reflectance-infra red spectroscopy. The scanning electron microscopy of the coated fabric revealed porous structure. The porosity of the material was 54-70% and the pore size was in the range of 75-120μm depending on the blend composition. The air permeability diminished as the PVP content increased. The water vapour transmission rate was in the range of 2000-3500g/m(2)day which may offer to be proper material for the wound dressing with moderate exudate absorption. Tetracycline hydrochloride was used as model drug within the hydrogel matrix. The cumulative release of drug was found to be ∼80% of the total loading after ∼48h. The drug loaded dressings showed good antimicrobial nature against both gram positive and gram negative bacteria. In vivo wound healing and tissue compatibility studies were carried out over a period of 21 days on full-thickness skin wounds created on male Wistar rats. Fast healing was observed in drug loaded dressing treated wounds with minimum scarring, as compared to the other groups. These results suggest that drug loaded dressing could provide scar preventive wound healing.

  3. [Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): a review].

    PubMed

    Ständer, S; Metze, D; Luger, T; Schwarz, T

    2013-08-01

    DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms), also known as hypersensitivity syndrome (HSS), is a severe and potentially life-threatening drug reaction. The worldwide rate of mortality is about 10 %, its incidence is increasing. Drugs that most frequently induce DRESS are aromatic anticonvulsive drugs (carbamazepine, lamotrigine, phenobarbital), and more recently new retroviral therapies. The pathogenesis of DRESS is not yet fully understood, but is certainly multifactorial involving a combination of immune reactions, ethnic predisposition, genetically determined enzyme deficiencies and reactivation of herpes viruses (HHV-6, HHV-7, EBV, CMV). Because of the involvement of the skin and internal organs, the clinical picture can be very variable. No specific clinical, histologic or laboratory parameter is available, so the diagnosis has to rely on the clinical appearance. The long latency period between start of drug intake and the initial manifestation of DRESS and the successive onset of skin and organ involvement complicates the early diagnosis. Although or even because DRESS represents a diagnostic challenge, detailed knowledge about this disease is of utmost importance to enable early therapeutic actions.

  4. Review of new topical hemostatic dressings for combat casualty care.

    PubMed

    Bennett, Brad L; Littlejohn, Lanny

    2014-05-01

    This review analyzes the new (2008-2013) hemostatic agents and dressings for enhanced efficacy in preclinical studies, and investigates supportive findings among case reports of effectiveness and safety in hospital and prehospital literature. A literature search was conducted using PubMed, National Library of Medicine using key words and phrases. The search revealed a total of 16 articles that fit the criteria established for third-generation hemostatic dressings. There were a total of 9 preclinical, 5 clinical, and 2 prehospital studies evaluated. Evaluation of these third-generation studies reveals that mucoadhesive (chitosan) dressings, particularly Celox Gauze and ChitoGauze, clearly show equal efficacy to Combat Gauze across many dependent variables. Chitosan-based products are ideal prehospital dressings because they are shown to work independently from the physiological clotting mechanisms. Many first-, second-, and third-generation chitosan-based dressings have been in use for years by the United States and other NATO militaries at the point of injury, and during tactical evacuation, in Operation Enduring Freedom and Operation Iraqi Freedom without reported complications or side effects. Based on the reported efficacy and long-term safety of chitosan-based products, increased use of Celox Gauze and ChitoGauze within the Department of Defense and civilian venues merits further consideration and open debate. PMID:24806495

  5. Assessing the effect of an antimicrobial wound dressing on biofilms.

    PubMed

    Percival, Steven L; Bowler, Phil; Woods, Emma J

    2008-01-01

    To date the effect of silver-containing wound dressings on biofilms, known to be present in chronic wounds, has not been determined or documented. In this current study, we aimed to determine the antimicrobial effect of a silver-containing dressing on biofilms grown in a chambered slide model. Before the addition of a wound dressing onto a 24-hour biofilm, composed of either Pseudomonas aeruginosa, Enterobacter cloacae, Staphylococcus aureus, or a mixed bacterial community, a fluorescent dye was applied. This enabled the viability of sessile bacteria to be monitored in real-time, using a rapid form of confocal laser scanning microscopy over a contact time period of 48 hours. By analyzing all the three-dimensional data generated from the confocal time-lapse sequences, 90% of all sessile bacteria within the biofilm were observed to progressively turn red (i.e., died) within 24 hours. Total bacterial kill in the biofilm was achieved after 48 hours. This research has shown that the dressing was effective in killing the tested bacteria evident in both the tested mono and polymicrobial biofilms, which provides valuable evidence that this dressing may have an effect on biofilms found in recalcitrant chronic wounds.

  6. Development of antimicrobial and scar preventive chitosan hydrogel wound dressings.

    PubMed

    Anjum, Sadiya; Arora, Abha; Alam, M S; Gupta, Bhuvanesh

    2016-07-11

    Antimicrobial and scar preventive wound dressings were developed by coating a blend of chitosan (CS), polyethylene glycol (PEG) and polyvinyl pyrolidone (PVP) on the cotton fabric and subsequent freeze drying. The miscibility of blend systems and functional group interaction were investigated by attenuated total reflectance-infra red spectroscopy. The scanning electron microscopy of the coated fabric revealed porous structure. The porosity of the material was 54-70% and the pore size was in the range of 75-120μm depending on the blend composition. The air permeability diminished as the PVP content increased. The water vapour transmission rate was in the range of 2000-3500g/m(2)day which may offer to be proper material for the wound dressing with moderate exudate absorption. Tetracycline hydrochloride was used as model drug within the hydrogel matrix. The cumulative release of drug was found to be ∼80% of the total loading after ∼48h. The drug loaded dressings showed good antimicrobial nature against both gram positive and gram negative bacteria. In vivo wound healing and tissue compatibility studies were carried out over a period of 21 days on full-thickness skin wounds created on male Wistar rats. Fast healing was observed in drug loaded dressing treated wounds with minimum scarring, as compared to the other groups. These results suggest that drug loaded dressing could provide scar preventive wound healing. PMID:27163526

  7. Wound dressing with sustained anti-microbial capability.

    PubMed

    Loke, W K; Lau, S K; Yong, L L; Khor, E; Sum, C K

    2000-01-01

    To overcome current limitations in wound dressings for treating mustard-burn induced septic wound injuries, a nonadherent wound dressing with sustained anti-microbial capability has been developed. The wound dressing consists of two layers: the upper layer is a carboxymethyl-chitin hydrogel material, while the lower layer is an anti-microbial impregnated biomaterial. The hydrogel layer acts as a mechanical and microbial barrier, and is capable of absorbing wound exudate. In physiological fluid, the carboxymethylated-chitin hydrogel swells considerably, imbibing up to 4 times its own weight of water and is also highly porous to water vapor. The moisture permeability of the dressing prevents the accumulation of fluid in heavily exudating wounds seen in second-degree burns. The lower layer, fabricated from chitosan acetate foam, is impregnated with chlorhexidine gluconate. From the in vitro release studies, the loading concentration was optimized to deliver sufficient anti-microbial drug into the wound area to sustain the anti-microbial activity for 24 h. The anti-microbial activity of the dressing against Pseudomonas aeruginosa and Staphylococcus aureus was tested using the Bauer-Kirby Disk Diffusion Test.

  8. Biotechnologically produced microbial alginate dressings show enhanced gel forming capacity compared to commercial alginate dressings of marine origin.

    PubMed

    Hoefer, Dirk; Schnepf, Julia K; Hammer, Timo R; Fischer, Melissa; Marquardt, Christoph

    2015-04-01

    Marine alginate fibre dressings are well established in wound management. Alginate fibres can absorb plenty of wound exudate due to their gel forming abilities and ion exchange. Alginates from bacteria have never been studied for medical applications so far, although the microbial polymer raises expectations for improved gelling capacity due to its unique O-acetylation. To prove the gelling capacity of bacterial alginate, we extracted the co-polymer from fermentation of the soil bacterium Azotobacter vinelandii ATCC 9046, cultivated on crude glycerol as an alternative carbon source. Bacterial alginate was isolated in high purity and extruded by a wet spinning method. Fibre structure and properties were characterised by infrared spectroscopy, NMR, GPC, scanning electron microscopy and tensile testing. The fibres could be processed into biocompatible needle web dressings, which showed more than twice the gel formation in saline compared to commercial dressings made of marine alginates. Gelled dressings of bacterial alginate formed stable hydrogels of sufficient shape and strength for wound healing applications. This work suggests that the increased gel formation of bacterial alginate from A. vinelandii may be optimal for the preparation of novel wound dressings.

  9. Co-Trimoxazole-Induced DRESS Syndrome: A Case Report.

    PubMed

    Paitorn, Limvorraphan

    2016-02-01

    Drug Rash with Eosinophilia and Systemic Symptoms (DRESS syndrome) is a severe adverse drug reaction. The drugs, which most commonly induce this condition, are anti-convulsants and sulfonamides. A 15-year-old Thai woman with no known underlying disease was prescribed co-trimoxazole, and two months after initiation, DRESS was diagnosed by RegiSCAR's score. Her clinical symptoms were fever laboratory abnormalities and maculopapular rash on her face, trunk and extremities. She was treated with antipyretics, antihistamines and steroid therapy, and her clinical and laboratory findings were restored to normal by the 10th day of treatment. Early diagnosis, discontinuation of the culprit drug, and management with steroids therapy can reduce the severity of DRESS syndrome. PMID:27266243

  10. Cross-dressing: an alternative mechanism for antigen presentation.

    PubMed

    Campana, Stefania; De Pasquale, Claudia; Carrega, Paolo; Ferlazzo, Guido; Bonaccorsi, Irene

    2015-12-01

    Cross-dressing involves the transfer of preformed functional peptide-MHC complexes from the surface of donor cells to recipient cells, such as dendritic cells (DCs). These cross-dressed cells might eventually present the intact, unprocessed peptide-MHC complexes to T lymphocytes. In this review we will discuss some recent findings concerning the intercellular transfer of preformed MHC complexes and the possible mechanisms by which the transfer may occur. We will report evidences showing that both MHC class I and MHC class II functional complexes might be transferred, highlighting the physiological relevance of these cross-dressed cells for the presentation of exogenous antigens to both cytotoxic and helper T lymphocytes.

  11. Expanding Dress Code Requirements in the Doctor of Pharmacy Program.

    PubMed

    Naughton, Cynthia A; Schweiger, Teresa A; Angelo, Lauren B; Lea Bonner, C; Dhing, Conrad W; Farley, Joel F

    2016-06-25

    Although the use of a professional dress code is standard practice across colleges and schools of pharmacy during introductory and advanced pharmacy practice experiences, requiring professional attire is not applied consistently during the didactic portion of students' education. There are arguments for and against the adoption of a professional dress code throughout the entire doctor of pharmacy program, including the classroom setting. Given uncertainty regarding the potential benefits and challenges that may arise from adopting a professional dress code in the didactic portion of a student pharmacist's education, it is perhaps not surprising that programs adopt disparate policies regarding its use. This exploration was conducted as part of a series of debates held in conjunction with the American Association of Colleges of Pharmacy's (AACP) Academic Leadership Fellows Program (ALFP) and was presented at the 2015 AACP Interim Meeting on February 7, 2015. PMID:27402977

  12. Expanding Dress Code Requirements in the Doctor of Pharmacy Program

    PubMed Central

    Schweiger, Teresa A.; Angelo, Lauren B.; Lea Bonner, C.; Dhing, Conrad W.; Farley, Joel F.

    2016-01-01

    Although the use of a professional dress code is standard practice across colleges and schools of pharmacy during introductory and advanced pharmacy practice experiences, requiring professional attire is not applied consistently during the didactic portion of students’ education. There are arguments for and against the adoption of a professional dress code throughout the entire doctor of pharmacy program, including the classroom setting. Given uncertainty regarding the potential benefits and challenges that may arise from adopting a professional dress code in the didactic portion of a student pharmacist’s education, it is perhaps not surprising that programs adopt disparate policies regarding its use. This exploration was conducted as part of a series of debates held in conjunction with the American Association of Colleges of Pharmacy’s (AACP) Academic Leadership Fellows Program (ALFP) and was presented at the 2015 AACP Interim Meeting on February 7, 2015. PMID:27402977

  13. Dust acoustic dressed soliton with dust charge fluctuations

    SciTech Connect

    Asgari, H.; Muniandy, S. V.; Wong, C. S.

    2010-06-15

    Modeling of dust acoustic solitons observed in dusty plasma experiment [Bandyopadhyay et al., Phys. Rev. Lett. 101, 065006 (2008)] using the Korteweg-de Vries (KdV) equation showed significant discrepancies in the regime of large amplitudes (or high soliton speed). In this paper, higher order perturbation corrections to the standard KdV soliton are proposed and the resulting dressed soliton is shown to describe the experimental data better, in particular, at high soliton speed. The effects of dust charge fluctuations on the dust acoustic dressed soliton in a dusty plasma system are also investigated. The KdV equation and a linear inhomogeneous equation, governing the evolution of first and second order potentials, respectively, are derived for the system by using reductive perturbation technique. Renormalization procedure is used to obtain nonsecular solutions of these coupled equations. The characteristics of dust acoustic dressed solitons with and without dust charge fluctuations are discussed.

  14. Dressing ignition and facial burns following orbital exenteration.

    PubMed

    Bajnrauh, Robert; Nguyen, Elizabeth V; Reifler, David M; Wilcox, Richard M

    2007-01-01

    A 49-year-old woman with type II diabetes mellitus and a history of smoking underwent partial eyelid-sparing exenteration of the right orbit and antifungal therapy for zygomycosis. The medial orbital wall healed with a 7-mm fistula to the ethmoid sinus and a moist granulating apex required daily dressing changes for several months. Eighteen weeks following surgery, the patient cleaned her face with an alcohol wipe and then lit a cigarette, igniting the dressing covering the exenterated eye socket. This caused severe burns to the periorbital regions of both eyes requiring debridement, allografts, and then split-thickness skin grafting. Factors predisposing to this unusual and serious complication of orbital exenteration are reviewed and the subjects of treatment and prevention are discussed. To our knowledge, this is the first reported case of dressing ignition with serious facial burns in a postexenteration patient.

  15. Use of fibre dressings in children with severe epidermolysis bullosa.

    PubMed

    Denyer, Jacqueline; Gibson, Elaine

    This non-comparative study explored the benefits of a natural gelling fibre dressing in 10 children with epidermolysis bullosa (EB). The clinical challenge in managing these children is that they often present with recalcitrant wounds that are perpetuated by critical colonisation, presence of biofilms and infection. KytoCel® (Aspen Medical) is a highly absorbent dressing composed of natural, biodegradable acylated chitosan. These fibres bond with wound exudate to form a clear gel that locks in fluid absorbs pathogens and is conformable to the wound bed. It also has haemostatic properties. ( Dutta PK et al, 2004 ; Lee et al, 2009 ; Stephen Haynes et al, 2014 ). Factors considered were whether the dressing could aid healing, reduce bleeding, reduce bioburden, be atraumatic and comfortable during wear time and removal.

  16. [Skin reaction to carbamazepine or DRESS syndrome: a case presentation].

    PubMed

    Cabrera Fundora, Emigdio Jesús; Cabrera Osorio, Yuliet; Cabrera Osorio, Claudia

    2016-02-25

    Carbamazepine is a frequently used drug that can produce adverse reactions like vertigo, somnolence and severe skin reactions like Drug Rash with Eosinophilia and Systemic Symptoms Syndrome (DRESS Syndrome). This syndrome is characterized by a late-appearing, slow-progressing cutaneous eruption accompanied by atypical lymphocytes, eosinophilia, and systemic symptoms such as fever, lymphadenopathy, hepatic compromise, and renal dysfunction that can be severe enough to cause death. We present a case that aims to highlight the importance of an early diagnosis of DRESS syndrome to adjust therapy and improve survival. The patient is a female patient prescribed carbamazepine for trigeminal neuralgia who presented with skin lesions, which were initially attributed to a hypersensitivity reaction. The lesions worsened in spite of treatment and systemic symptoms ensued. A diagnosis of DRESS syndrome was proposed and steroid treatment was initiated with rapid improvement.

  17. Dissipationless electron transport in photon-dressed nanostructures.

    PubMed

    Kibis, O V

    2011-09-01

    It is shown that the electron coupling to photons in field-dressed nanostructures can result in the ground electron-photon state with a nonzero electric current. Since the current is associated with the ground state, it flows without the Joule heating of the nanostructure and is nondissipative. Such a dissipationless electron transport can be realized in strongly coupled electron-photon systems with the broken time-reversal symmetry--particularly, in quantum rings and chiral nanostructures dressed by circularly polarized photons. PMID:21981519

  18. Speeding up Adiabatic Quantum State Transfer by Using Dressed States

    NASA Astrophysics Data System (ADS)

    Baksic, Alexandre; Ribeiro, Hugo; Clerk, Aashish A.

    2016-06-01

    We develop new pulse schemes to significantly speed up adiabatic state transfer protocols. Our general strategy involves adding corrections to an initial control Hamiltonian that harness nonadiabatic transitions. These corrections define a set of dressed states that the system follows exactly during the state transfer. We apply this approach to stimulated Raman adiabatic passage protocols and show that a suitable choice of dressed states allows one to design fast protocols that do not require additional couplings, while simultaneously minimizing the occupancy of the "intermediate" level.

  19. An alternative buildup material: combine dressing and liquid paraffin.

    PubMed

    Rykers, K; Trenkner, S

    1998-01-01

    A tissue substitute of combine dressing (gauze and cottonwool) soaked with liquid paraffin was found to be a practical, easily manufactured and inexpensive buildup material for use in treating radiation therapy patients with electron and photon beams. Tissue equivalence was measured for electron energies of 6, 9, 12, and 16 MeV and photon energies of 6 MV and 10 MV delivered by a Varian 2100C linear accelerator. The solid water equivalence of the combine dressing/liquid paraffin material was approximately 1.2 times the geometric thickness of tissue substitute material across all energies.

  20. Evaluation of a flexible new liquid polymer wound dressing.

    PubMed

    Hsiung, Sherry H; Robins, Perry

    2005-01-01

    Occlusive dressings are the foundation of wound care and have been shown to speed epithelialization and healing of surgical sites. Many different dressings have been introduced over the years including antibacterial ointments with gauze and adhesive, hydrocolloid bandages, and liquid adhesives. All of these have their limitations and advantages. We introduce our experience with a new organic polymer in solvent which when applied to a wound forms a flexible occlusive bandage. The material has been shown to have antimicrobial properties and be well-tolerated by patients.

  1. Leflunomide-induced DRESS syndrome with renal involvement and vasculitis.

    PubMed

    Pinto, Benzeeta; Dhir, Varun; Krishnan, Sabari; Nada, Ritambhra

    2013-05-01

    DRESS or drug reaction (or rash) with eosinophilia and systemic symptoms belongs to the severe cutaneous adverse reaction group and is characterized by hematological abnormalities and visceral organ involvement. Although most often related with anticonvulsant and sulfonamide use, it is reported with numerous other drugs. We report an unusual case of DRESS syndrome due to Leflunomide, also complicated by renal involvement in the form of granulomatous interstitial nephritis and vasculitis. On a review of the literature, eight similar cases were found, and these are discussed.

  2. Hemicellulose dressing versus rayon dressing in the re-epithelialization of split-thickness skin graft donor sites: a multicenter study.

    PubMed

    Ferreira, Lydia M; Blanes, Leila; Gragnani, Alfredo; Veiga, Daniela F; Veiga, Frederico P; Nery, Gilka B; Rocha, Gustavo Henrique H R; Gomes, Heitor C; Rocha, Mario G; Okamoto, Regina

    2009-08-01

    The aim of this study was to compare the effectiveness of a hemicellulose dressing with that of rayon dressing in the healing of split-thickness skin graft donor sites. Twenty-eight patients were selected from five different hospitals and randomized into two groups: hemicellulose dressing group and rayon dressing group. All patients underwent split-thickness skin grafting for various reasons, and the skin graft donor site wounds were covered with hemicellulose dressing (n=14) or rayon dressing (n=14). The donor site was assessed on postoperative days 1, 7, 14, 21, and 28 for hyperemia, pruritus, pain, exudate level, and adherence of the wound dressing. At the 60-day follow-up visit, the donor site was assessed again for pruritus and pain. Touch-pressure, thermal, and pain sensibility tests were performed preoperatively and on postoperative day 60 together with the assessment of color and texture of the re-epithelialized area. In all patients, re-epithelialization was completed between 14 and 21 days after surgery. There were no significant differences between the two groups with regard to pain, hyperemia, pruritus, exudate, and final appearance (color and texture) of the skin graft donor site. The rayon dressing provided significantly better adherence than the hemicellulose dressing, and both dressings showed similar results with regard to the parameters evaluated when used in the treatment of split-thickness skin graft donor sites.

  3. Evaluation of gaseous transmission (O2 and CO2) through burn wound dressings.

    PubMed

    Queen, D; Gaylor, J D; Evans, J H; Courtney, J M; Reid, W H

    1987-10-01

    The rates of transmission of oxygen and carbon dioxide through various burn wound dressing materials were determined. The British Standard Vacuum technique was used to determine the Gas Transmission Rate (GTR) of hydrophobic dressings. A Gas to Liquid technique was used to determine the GTR of hydrophilic (water containing) dressings. All the materials tested showed greater GTR values for carbon dioxide than for oxygen. The role of the transmission characteristics of the dressings to influence the wound healing environment is discussed.

  4. Similarities between Students Receiving Dress Code Violations and Discipline Referrals at Newport Junior High School

    ERIC Educational Resources Information Center

    Nicholson, Nikki

    2007-01-01

    Background: Looking at dress code violations and demographics surrounding kids breaking the rules. Purpose: To see if there is a connection between dress code violations and discipline referrals. Setting: Jr. High School; Study Sample: Students with dress code violations for one week; Intervention: N/A; Research Design: Correlational; and Control…

  5. The role of hydrogel dressings in prophylactic sets used by soldiers involved in Polish military contingents.

    PubMed

    Ziemba, Radosław

    2013-01-01

    This paper describes the available production technology of hydrogel dressings. Their practical application were tested--solid and semi-liquid--in the daily practice of medical emergency. An analysis was made of risk associated with the application of these type of dressings, and of the ability to apply them in individual prophylactic sets. The aim of the study was to compare commercially available hydrogel dressings--to the conditions and the risk of their use. Anti-burn dressings were used of three different companies, provided for the research in original packaging. The study was conducted in the laboratory. The samples of dressings were placed on a thermally insulating surface, and then for a period of 60 h with a thermocouple the temperature was measured under the dressing. The measured values were compared with measurements effected parallel to the ambient temperature. The implementation of the dressing on the surface resulted in the immediate cooling of the surface (about 10 min). Time after application of the dressing to achieve its full cooling capacity is approximately 60 min for each of the tested dressings. The maximum reduction in temperature of cooled surface was analogous for the three tested dressings and was 4.20 degrees C. Maximum cooling times of dressings differed significantly. In conclusion, the dressings in the form of solid hydrogels are characterized by an easier application, they are safe during oxygen therapy and they provide a longer cooling time.

  6. Rationales and Norms for Teacher Dress Codes: A Review of Employee Handbooks

    ERIC Educational Resources Information Center

    Freeburg, Beth W.; Workman, Jane E.; Arnett, Sally E.; Robinson, Joyce R.

    2011-01-01

    The research question was "What dress norms and related rationales are found in teacher dress policies?" Data were 102 school employee handbooks. Eighty-two handbooks (80.4%) provided one or more rationale, most frequently being "To project a positive image in the community" (n = 56). Dress norms, categorized as broad and itemized, were determined…

  7. Dress Codes in Post-Apartheid South African Workplaces

    ERIC Educational Resources Information Center

    Grant, Terri; Nodoba, Gaontebale

    2009-01-01

    There are many factors that influence dress code decision making in formal and informal business arenas. In South Africa, with its colonial and apartheid history followed by an exuberant resurgence of Africanism, factors such as diversity of race, ethnicity, religion, and culture play a critical role in lifestyle and worldview. These many and…

  8. Prevention of dressing slippage under an elastic bandage.

    PubMed

    Sawada, Y; Yotsuyanagi, T

    1992-06-01

    A technique is described to prevent the shift in position of dressing materials by applying a double-sided adhesive tape between the skin and the elastic bandage. This technique also prevents a shift in position of a pressure garment, especially when applied around joints on the extremities.

  9. Keratin dressings speed epithelialization of deep partial-thickness wounds.

    PubMed

    Pechter, Patricia M; Gil, Joel; Valdes, Jose; Tomic-Canic, Marjana; Pastar, Irena; Stojadinovic, Olivera; Kirsner, Robert S; Davis, Stephen C

    2012-01-01

    Keratin gene expression is regarded as a hallmark of epidermal biology. It demarcates the three keratinocyte phenotypes: basal (expressing KRT5 and KRT14), differentiating (expressing KRT1 and KRT10), and activated (wound healing), which is characterized by expression of KRT6, KRT16, and KRT17. Activated keratinocytes are among the first signals of epidermal wound healing. In addition, they are found deregulated in nonhealing chronic wounds. To examine keratins as a potential modality for wound-healing disorders, we evaluated two different keratin dressings, liquid or solid, and assessed their effects of epithelialization and closure using porcine partial-thickness wound-healing model in vivo. We found that both forms of keratin dressings accelerated closure and epithelialization, achieving statistically significant differences on day 5. Evidence suggesting early onset of epithelialization was corroborated further by gene expression analyses revealing induction of KRT6A, KRT16, and KRT17 by day 2 postwounding. The data suggest that keratin dressings may stimulate epithelialization by enhancing the activation of keratinocytes. We conclude that keratin-containing dressings can accelerate wound healing and closure. Further studies are needed to determine the molecular mechanisms of this activation.

  10. Cyclodextrin-based hydrogels toward improved wound dressings.

    PubMed

    Pinho, Eva; Grootveld, Martin; Soares, Graça; Henriques, Mariana

    2014-12-01

    Optimal wound dressings should be capable of mechanical wound protection and also facilitate the healing process via maintenance of suitable environmental conditions and the controlled delivery of bioactive molecules. Hydrogels present suitable properties for wound-dressing applications such as good biocompatibility, together with a high water content, the latter of which is important for the maintenance of a moist environment and ready removal from the wound with a minimal level of associated pain. However, their properties as drug delivery systems can be improved by the use of cyclodextrins as cross-linking agents. Cyclodextrins have been extensively used as "carriers" on food, textile, cosmetic and, most especially, in the pharmaceutical industry in view of their powerful complexation abilities and biocompatibilities, together with further desirable characteristics. The conjugation of cyclodextrins with hydrogels may allow the achievement of an optimal wound-dressing material, because the hydrogel component will maintain the moist environment required for the healing process, and the cyclodextrin moiety has the ability to protect and modulate the release of bioactive molecules. Therefore, this review aims to gather information regarding cyclodextrin-based hydrogels for possible wound-dressing applications.

  11. 9 CFR 108.9 - Dressing rooms and other facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Dressing rooms and other facilities. 108.9 Section 108.9 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... running water, soap, towels, and the like. They shall be in sufficient number, ample in size,...

  12. 9 CFR 108.9 - Dressing rooms and other facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Dressing rooms and other facilities. 108.9 Section 108.9 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... running water, soap, towels, and the like. They shall be in sufficient number, ample in size,...

  13. 9 CFR 108.9 - Dressing rooms and other facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Dressing rooms and other facilities. 108.9 Section 108.9 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... running water, soap, towels, and the like. They shall be in sufficient number, ample in size,...

  14. 9 CFR 108.9 - Dressing rooms and other facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Dressing rooms and other facilities. 108.9 Section 108.9 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... running water, soap, towels, and the like. They shall be in sufficient number, ample in size,...

  15. 9 CFR 108.9 - Dressing rooms and other facilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Dressing rooms and other facilities. 108.9 Section 108.9 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... running water, soap, towels, and the like. They shall be in sufficient number, ample in size,...

  16. Seed dressings to control slug damage in oilseed rape.

    PubMed

    Simms, Louise C; Mullins, Christopher E; Wilson, Michael J

    2002-07-01

    Slugs are major pests of oilseed rape that are poorly controlled by conventional bait pellets. A series of laboratory experiments investigated the potential of seed-dressings to control slug damage in this crop. Four compounds: metaldehyde, methiocarb, cinnamamide and 3,5-dimethoxycinnamic acid (DMCA) were tested at a range of doses for phytotoxicity and ability to reduce damage by Deroceras reticulatum (Müller). Metaldehyde and methiocarb were not phytotoxic at any doses, whereas all doses of cinnamamide and DMCA were. All compounds reduced slug damage, but metaldehyde and methiocarb consistently performed better than cinnamamide and DMCA. Metaldehyde and methiocarb seed-dressings were compared with baited pellets containing the same active ingredients at recommended field doses. The seed-dressings protected plants from damage by D reticulatum and Arion subfuscus (Draparnaud) as well as, or better than, baited pellets. We therefore recommend that metaldehyde and methiocarb should be field-tested as seed dressings to control slugs in oilseed rape. PMID:12146169

  17. Dressed to Present: Ratings of Classroom Presentations Vary with Attire

    ERIC Educational Resources Information Center

    Gurung, Regan A. R.; Kempen, Laura; Klemm, Kayla; Senn, Rebecca; Wysocki, Rosie

    2014-01-01

    This study investigates the effects of formality of dress on ratings of classroom presentations. Participants (N = 65, 66% women) from a Midwestern university in the United States rated three female students giving a presentation designed for a health psychology class in one of four outfits: casual, party, business casual, or business formal.…

  18. French national wound management survey: choice criteria of dressings.

    PubMed

    Meaume, Sylvie; Barrois, Brigitte; Faucher, Nathalie

    Across Europe, wound care management is organized differently, and in some countries such as the UK or Denmark, wound healing centres have been implemented. In France, a large number of health professionals are not sufficiently educated in wound care management during their vocational training. The rapid evolution of dressings has changed wound management practices and has given rise to new professional recommendations. This national survey was carried out in France in 2009, including 465 health professionals, to determine the criteria they use to choose a dressing and their habits of care with acute or chronic wounds. Around 73% of respondents were nurses and, on average, participants took care of 43 wounds per month. It was also found that 89% of the health professionals who took part prefer the sequential treatment of the wound based on its appearance. Regardless of whether the wound is acute or chronic, the priorities for wound care and the choice of dressing are the management of the exudate and the prevention or treatment of infection. These results put into evidence the adequacy of the recommendations by these practitioners and the good correlation between the choice of dressing and the local therapeutic goal. To reach the same level of expertise, the professional training for health professionals who are less frequently involved in wound care is necessary.

  19. Lasers without inversion: Interference of dressed lifetime-broadened states

    SciTech Connect

    Imamoglu, A.; Harris, S.E.

    1989-12-15

    We describe the use of a coupling electromagnetic field to provide a general method of producing inversion-free laser systems. The interference between dressed states produces a zero in absorption while allowing gains of the order of that of the uncoupled system.

  20. Moving beyond Dance, Dress, and Dining in Multicultural Canada

    ERIC Educational Resources Information Center

    Sensoy, Ozlem; Sanghera, Raj; Parmar, Geetu; Parhar, Nisha; Nosyk, Lianne; Anderson, Monica

    2010-01-01

    The mainstream curriculum is extremely efficient in furthering a neoliberal multicultural discourse, what is described as the dance, dress, and dining, or heroes and holidays, or Taco Tuesday approaches to diversity. Given this, doing anything else is an ongoing challenge. This paper shares details of a government-university-school collaboration…

  1. 21 CFR 878.4018 - Hydrophilic wound dressing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Hydrophilic wound dressing. 878.4018 Section 878.4018 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4018 Hydrophilic wound...

  2. 21 CFR 878.4018 - Hydrophilic wound dressing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Hydrophilic wound dressing. 878.4018 Section 878.4018 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4018 Hydrophilic wound...

  3. 21 CFR 878.4018 - Hydrophilic wound dressing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hydrophilic wound dressing. 878.4018 Section 878.4018 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4018 Hydrophilic wound...

  4. 21 CFR 878.4018 - Hydrophilic wound dressing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Hydrophilic wound dressing. 878.4018 Section 878.4018 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4018 Hydrophilic wound...

  5. 21 CFR 878.4490 - Absorbable hemostatic agent and dressing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Absorbable hemostatic agent and dressing. 878.4490 Section 878.4490 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4490...

  6. 21 CFR 878.4490 - Absorbable hemostatic agent and dressing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Absorbable hemostatic agent and dressing. 878.4490 Section 878.4490 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4490...

  7. 21 CFR 878.4490 - Absorbable hemostatic agent and dressing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Absorbable hemostatic agent and dressing. 878.4490 Section 878.4490 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4490...

  8. 21 CFR 878.4020 - Occlusive wound dressing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Occlusive wound dressing. 878.4020 Section 878.4020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4020 Occlusive wound...

  9. 21 CFR 878.4018 - Hydrophilic wound dressing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Hydrophilic wound dressing. 878.4018 Section 878.4018 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4018 Hydrophilic wound...

  10. 21 CFR 878.4020 - Occlusive wound dressing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Occlusive wound dressing. 878.4020 Section 878.4020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4020 Occlusive wound...

  11. 21 CFR 878.4020 - Occlusive wound dressing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Occlusive wound dressing. 878.4020 Section 878.4020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4020 Occlusive wound...

  12. 21 CFR 878.4490 - Absorbable hemostatic agent and dressing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Absorbable hemostatic agent and dressing. 878.4490 Section 878.4490 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4490...

  13. 21 CFR 878.4020 - Occlusive wound dressing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Occlusive wound dressing. 878.4020 Section 878.4020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4020 Occlusive wound...

  14. 21 CFR 878.4490 - Absorbable hemostatic agent and dressing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Absorbable hemostatic agent and dressing. 878.4490 Section 878.4490 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4490...

  15. 21 CFR 878.4020 - Occlusive wound dressing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Occlusive wound dressing. 878.4020 Section 878.4020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Surgical Devices § 878.4020 Occlusive wound...

  16. Students' Rights in Mississippi on Matters of Dress and Grooming.

    ERIC Educational Resources Information Center

    Robbins, Jerry H.

    In the past few years numerous cases have appeared before the courts concerning the dress and grooming of students. In many of these cases, the issue has been related to male students' hair length. Throughout the nation, conflicting trends have emerged from a legal point of view, and the issues remain largely unresolved. This paper discusses the…

  17. Good-by to Dress Codes--for Now.

    ERIC Educational Resources Information Center

    Johnson, Bettye

    1979-01-01

    Strict dress codes have been virtually eliminated in the public schools, particularly those regulations for hair length and style. The existing grooming policies are general and deal mainly with cleanliness, neatness, appropriateness, safety, health, and nondisruption of the learning environment. (Author)

  18. Pants and Hats: Dress Codes and Expressive Conduct as Speech.

    ERIC Educational Resources Information Center

    DeMitchell, Todd A.

    1999-01-01

    It has been 30 years since the U.S. Supreme Court, in the "Tinker" case, upheld three students' right to wear black armbands protesting the Vietnam War to school. Recent cases involving sagging pants and an African headwrap (dress code violations) did not meet allowable "free-speech" requirements. (MLH)

  19. Real-time monitoring of moisture levels in wound dressings in vitro: an experimental study.

    PubMed

    McColl, David; Cartlidge, Brian; Connolly, Patricia

    2007-10-01

    Retaining an appropriate level of moisture at the interface between a healing wound and an applied dressing is considered to be critical for effective wound healing. Failure to control exudate at this interface can result in maceration or drying out of the wound surface. The ability to control moisture balance at the wound interface is therefore a key aspect of wound dressing performance. To date it has not been possible to monitor in any effective manner the distribution of moisture within dressings or how this varies with time. A new measurement system is presented based on sensors placed at the wound/dressing interface which are capable of monitoring moisture levels in real time. The system comprises a model wound bed and sensor array complete with fluid injection path to mimic exudate flow. Eight monitoring points, situated beneath the test dressing, allow the moisture profile across the complete dressing to be measured both during and after fluid injection. The system has been used to evaluate the performance of four foam dressings, a composite hydrofibre dressing and a film dressing. Stark contrasts in the performance of the wound contact layer were found between the different wound dressing types. The composite hydrofibre dressing retained moisture at the wound interface throughout the experiments while areas of the foam dressing quickly became dry, even during constant injection of fluid. The abundance of sensors allowed a moisture map of the surface of the wound dressing to be constructed, illustrating that the moisture profile was not uniform across several of the dressings tested during absorption and evaporation of liquid. These results raise questions as to how the dressings behave on a wound in vivo and indicate the need for a similar clinical monitoring system for tracking wound moisture levels.

  20. [Combined polyurethane foam and hydrogel dressing. Outcome in lesions of diverse etiology].

    PubMed

    Rueda López, Justo; Arboix Perejamo, Montserrat; Muñoz Bueno, Ana Maria; Rosell Moreno, Carmen; Blanco Blanco, Joan; Ballester Torralba, Jordi; Gago Fornells, Manuel; García González, R Fernando

    2004-11-01

    The authors present an observational evaluation on the effectiveness of a dressing included in the Indafoam brand for treatment of skin lesions due to different etiology which have an acute or chronic diagnosis; the authors include some very valuable information for professionals who use combined polyurethane foam and hydrogel dressings in their daily practice. Due to their composition, these dressings may be considered combined dressings having only one structure which maintains a stable temperature at the lesion site; these dressings have a high absorption capacity which prevents maceration of the skin surrounding lesions and protects lesions from contamination by exogenous germs.

  1. Are chlorhexidine-containing dressings safe for use with ventricular drainages?

    PubMed

    Scheithauer, S; Möller, M; Höllig, A; Marx, G; Thoröe, S; Lopez-Gonzalez, L; Reinges, M H T; Lemmen, S W

    2014-06-01

    The purpose of this report was to assess the safety and application of chlorhexidine (CHG)-containing dressings--shown to reduce central line infection rates markedly--for external ventricular drainages (EVDs) and lumbar drainages (LDs). Cerebrospinal fluid samples of patients receiving standard dressings and CHG-containing dressing (ten each) were analyzed by high-performance liquid chromatography for the presence of CHG. The application was evaluated. CHG was not detectable in all samples. The dressings' application for EVDs and LDs worked without problems. Thus, the use of CHG-containing dressings for EVDs and LDs seems to be safe. Further studies addressing their infection reduction potential are warranted.

  2. The use of bioactive wound dressing, stimulating epithelial regeneration of IIIa-degree burn wounds.

    PubMed

    Ermolov, A S; Smirnov, S V; Khvatov, V B; Istranov, L P; Koniushko, O I; Kolokolchikova, E G; Sychevsky, M V; Bocharova, V S

    2008-07-01

    Clinical and morphological comparison of wound healing after transplantation of living cultured allofibroblast on days 1-2 after the injury, collagen-1-based dressing with PDGF-BB, and traditional dressing with levomecol ointment showed that bioactive dressing accelerated wound epithelialization (5-7 days vs. 20-22 days with gauze dressing); the incidence of suppurative complications decreased, no crust formed, and epithelialization was not associated with the formation of a hypertrophic cicatrix. Biological dressing based on living cultured allofibroblasts and collagen-1 with PDGF-BB exhibited equal stimulatory effects on burn wound healing.

  3. Novel Asymmetric Wettable AgNPs/Chitosan Wound Dressing: In Vitro and In Vivo Evaluation.

    PubMed

    Liang, Donghui; Lu, Zhong; Yang, Hao; Gao, Jingting; Chen, Rong

    2016-02-17

    A novel silver nanoparticles (AgNPs)/chitosan composite dressing with asymmetric wettability surfaces was successfully prepared via a simple two-step method for biomedical applications as wound healing materials. First, AgNPs were assembled into the chitosan sponge which was prepared by lyophilization process. Then one side of the sponge was modified by a thin layer of stearic acid. The incorporation of AgNPs into chitosan dressing could enhance the antibacterial activity against drug-sensitive and drug-resistant pathogenic bacteria. The asymmetric surface modification endows the dressing with both highly hydrophobic property and inherent hydrophilic nature of chitosan. The hydrophobic surface of the dressing shows waterproof and antiadhesion for contaminant properties, whereas the hydrophilic surface preserves its water-absorbing capability and efficiently inhibits the growth of bacteria. Furthermore, the AgNPs/chitosan composite dressing displays improved moisture retention and blood clotting ability compared to the unmodified dressings. Cytocompatibility test evaluated in vitro and in a wound infection model illustrates the nontoxic nature of the composite dressing. More importantly, the in vivo wound healing model evaluation in mice reveals that the asymmetric AgNPs/chitosan dressing promotes the wound healing and accelerates the reepithelialization and collagen deposition. The silver accumulation in mice body treated by the composite dressing is far lower than that of the clinically used Acasin nanosilver dressing treated mice. This work indicates the huge potential of the novel AgNPs/chitosan wound dressing with asymmetrical wettability for clinical use. PMID:26800283

  4. A comparative study to evaluate the effect of honey dressing and silver sulfadiazene dressing on wound healing in burn patients.

    PubMed

    Baghel, P S; Shukla, S; Mathur, R K; Randa, R

    2009-07-01

    To compare the effect of honey dressing and silver-sulfadiazene (SSD) dressing on wound healing in burn patients. Patients (n=78) of both sexes, with age group between 10 and 50 years and with first and second degree of burn of less than 50% of TBSA (Total body surface area) were included in the study, over a period of 2 years (2006-08). After stabilization, patients were randomly attributed into two groups: 'honey group' and 'SSD group'. Time elapsed since burn was recorded. After washing with normal saline, undiluted pure honey was applied over the wounds of patients in the honey group (n=37) and SSD cream over the wounds of patients in SSD group (n=41), everyday. Wound was dressed with sterile gauze, cotton pads and bandaged. Status of the wound was assessed every third and seventh day and on the day of completion of study. Patients were followed up every fortnight till epithelialization. The bacteriological examination of the wound was done every seventh day. The mean age for case (honey group) and control (SSD group) was 34.5 years and 28.5 years, respectively. Wound swab culture was positive in 29 out of 36 patients who came within 8 hours of burn and in all patients who came after 24 hours. The average duration of healing in patients treated with honey and SSD dressing at any time of admission was 18.16 and 32.68 days, respectively. Wound of all those patients (100%) who reported within 1 hour became sterile with honey dressing in less than 7 days while none with SSD. All of the wounds became sterile in less than 21 days with honey, while tthis was so in only 36.5% with SSD treated wounds. The honey group included 33 patients reported within 24 hour of injury, and 26 out of them had complete outcome at 2 months of follow-up, while numbers for the SSD group were 32 and 12. Complete outcome for any admission point of time after 2 months was noted in 81% and 37% of patients in the honey group and the SSD group. Honey dressing improves wound healing, makes the

  5. Evaluation of a foam dressing for acute and chronic wound exudate management.

    PubMed

    Bullough, Lindsay; Johnson, Sue; Forder, Rebecca

    2015-09-01

    This article discusses the use of a foam dressing for exudate management in both chronic and acute wounds, such as surgical wounds, pressure ulcers, diabetic ulcers, trauma wounds, and leg ulcers. The primary objective of the study was to observe patients' wound progression in terms of wound size and the condition of the wound bed, when using this foam dressing as either a primary or secondary dressing. The outcome of the evaluation demonstrated that ActivHeal Foam Contact dressing effectively managed exudate. It was also observed that the dressing can assist in autolysis and support improvements in peri-wound status. Choosing an appropriate dressing to manage a wound is essential. Clinicians working in the NHS are under pressure to deliver good-quality clinical outcomes, and the ActivHeal Foam Contact dressing supports this outcome.

  6. Evaluation of a no-dressing intervention for tunneled central venous catheter exit sites.

    PubMed

    Olson, Karin; Rennie, Robert P; Hanson, John; Ryan, Mary; Gilpin, Jean; Falsetti, Maria; Heffner, Thea; Gaudet, Shirley

    2004-01-01

    This study tested whether central venous catheter (CVC)-related sepsis could be reduced by removing a hypothesized reservoir for pathogens, the CVC exit site dressing. Seventy-eight individuals with cancer, stratified for gender (37 men and 41 women) and transplant status, with newly inserted CVCs were recruited and randomly assigned to receive either a gauze dressing or no dressing, once their catheter insertion site had healed (3 weeks). Because there was no difference in CVC-related septic episodes based on gender or transplant status, the stratification was not maintained for remaining analyses. Although there was no significant difference in CVC-related septic episodes (P =.28) or rehospitalization rates (P =.41) because of CVC-related sepsis between the dressing and no-dressing group, individuals in the dressing group developed CVC-related sepsis sooner (P =.02) than did individuals in the no-dressing group.

  7. Controlling the transition of bright and dark states via scanning dressing field

    NASA Astrophysics Data System (ADS)

    Li, Peiying; Zheng, Huaibin; Zhang, Yiqi; Sun, Jia; Li, Changbiao; Huang, Gaoping; Zhang, Zhaoyang; Li, Yuanyuan; Zhang, Yanpeng

    2013-03-01

    We report the transitions between the bright and dark states of singly-dressed four-wave mixing (FWM) and doubly-dressed FWMs, and the corresponding probe transmissions by scanning the dressing field frequency detuning in a five-level atomic system. Moreover, doubly-dressed six-wave mixing with avoided-crossing plots and triple-dressed eight-wave mixing with the comparison of scanning probe field and dressing field are studied. Such controlled transitions of the nonlinear optical signals can be realizable not only in atomic vapors but also in solid medium. The investigations maybe have potential applications in optical communication, quantum information processing and optoelectronic devices, and maybe also provide a sensitive probe method to study the dressing effect.

  8. Optimization of the dressing parameters in cylindrical grinding based on a generalized utility function

    NASA Astrophysics Data System (ADS)

    Aleksandrova, Irina

    2016-01-01

    The existing studies, concerning the dressing process, focus on the major influence of the dressing conditions on the grinding response variables. However, the choice of the dressing conditions is often made, based on the experience of the qualified staff or using data from reference books. The optimal dressing parameters, which are only valid for the particular methods and dressing and grinding conditions, are also used. The paper presents a methodology for optimization of the dressing parameters in cylindrical grinding. The generalized utility function has been chosen as an optimization parameter. It is a complex indicator determining the economic, dynamic and manufacturing characteristics of the grinding process. The developed methodology is implemented for the dressing of aluminium oxide grinding wheels by using experimental diamond roller dressers with different grit sizes made of medium- and high-strength synthetic diamonds type ??32 and ??80. To solve the optimization problem, a model of the generalized utility function is created which reflects the complex impact of dressing parameters. The model is built based on the results from the conducted complex study and modeling of the grinding wheel lifetime, cutting ability, production rate and cutting forces during grinding. They are closely related to the dressing conditions (dressing speed ratio, radial in-feed of the diamond roller dresser and dress-out time), the diamond roller dresser grit size/grinding wheel grit size ratio, the type of synthetic diamonds and the direction of dressing. Some dressing parameters are determined for which the generalized utility function has a maximum and which guarantee an optimum combination of the following: the lifetime and cutting ability of the abrasive wheels, the tangential cutting force magnitude and the production rate of the grinding process. The results obtained prove the possibility of control and optimization of grinding by selecting particular dressing

  9. [Clinical evaluation of hydrocolloidal dressing in 147 patients undergoing cardiovascular surgery].

    PubMed

    Ogawa, Mitsugu; Tsukui, H; Ishii, H; Yokoyama, S; Koh, E

    2005-07-01

    Recent evidence has suggested that a moist environment plays an important role in wound healing. Karayahesive, one type of hydrocolloidal dressing, contains natural karaya gum as a hydrophilic gel. We applied hydrocolloidal dressing to operative wounds in 147 patients who underwent cardiovascular surgery from April 2001 through August 2002 to evaluate its clinical usefulness. The dressing was kept on the wounds for 7 days after operation, but was immediately switched to conventional dressing with gauze if there was any problem. A total of 144 patients (98%) had no wound chest infections. Good wound healing was obtained with only 1 dressing, removed 7 days after operation, in 128 patients (87%). In 19 patients (13%), the hydrocolloidal dressing was switched to conventional dressing. In 13 of these patients the hydrocolloidal dressing dissolved naturally or exudation occurred; clinically, there were no local problems; however, 3 patients had infection, 2 had fat necrosis, and 1 had burn injury caused by electrocautery. No patients had skin problems caused by this dressing. We conclude that hydrocolloidal dressing can be used safely and effectively in patients undergoing cardiovascular surgery and reduce the workload of healthcare workers.

  10. Development of a novel antimicrobial seaweed extract-based hydrogel wound dressing.

    PubMed

    Tan, Shiau Pin; McLoughlin, Peter; O'Sullivan, Laurie; Prieto, Maria Luz; Gardiner, Gillian E; Lawlor, Peadar G; Hughes, Helen

    2013-11-01

    The objective of this study was to develop a novel antimicrobial seaweed wound dressing. The seaweed extract was active against nine clinically-relevant wound pathogens. A hydrogel formulation was prepared using polyvinyl alcohol (PVA) and polyvinylpyrrolidone (PVP), followed by addition of 1% seaweed extract. The antimicrobial properties of the novel dressing were tested using agar diffusion assays, with release-profiles examined using gel leaching and gel transfer assays. The dressing was found to be effective against the same microbial strains as the seaweed extract, with similar efficacy to the commonly used silver-based dressing, Acticoat(®). Antimicrobial release-profile assays revealed that the dressing was effective in inhibiting 70-90% of the bacterial population within the first 30 min, followed by a long, sustained released up to 97 h, without leaving a residue following five subsequent transfers of the dressing. Antimicrobial activity was stable for up to 6 months of storage at 4 °C, but activity was reduced slightly after 15 weeks. Following autoclave sterilization, the dressing displayed a slower release profile compared to a non-autoclaved counterpart. Hence, the seaweed dressing may have commercial applications, potentially competing with silver-based dressings at a lower cost per-application. This is the first report of development of a seaweed-based antimicrobial dressing.

  11. Dressing the post-Newtonian two-body problem and classical effective field theory

    NASA Astrophysics Data System (ADS)

    Kol, Barak; Smolkin, Michael

    2009-12-01

    We apply a dressed perturbation theory to better organize and economize the computation of high orders of the 2-body effective action of an inspiralling post-Newtonian (PN) gravitating binary. We use the effective field theory approach with the nonrelativistic field decomposition (NRG fields). For that purpose we develop quite generally the dressing theory of a nonlinear classical field theory coupled to pointlike sources. We introduce dressed charges and propagators, but unlike the quantum theory there are no dressed bulk vertices. The dressed quantities are found to obey recursive integral equations which succinctly encode parts of the diagrammatic expansion, and are the classical version of the Schwinger-Dyson equations. Actually, the classical equations are somewhat stronger since they involve only finitely many quantities, unlike the quantum theory. Classical diagrams are shown to factorize exactly when they contain nonlinear worldline vertices, and we classify all the possible topologies of irreducible diagrams for low loop numbers. We apply the dressing program to our post-Newtonian case of interest. The dressed charges consist of the dressed energy-momentum tensor after a nonrelativistic decomposition, and we compute all dressed charges (in the harmonic gauge) appearing up to 2PN in the 2-body effective action (and more). We determine the irreducible skeleton diagrams up to 3PN and we employ the dressed charges to compute several terms beyond 2PN.

  12. Control of electronic transport in graphene by electromagnetic dressing.

    PubMed

    Kristinsson, K; Kibis, O V; Morina, S; Shelykh, I A

    2016-01-01

    We demonstrated theoretically that the renormalization of the electron energy spectrum near the Dirac point of graphene by a strong high-frequency electromagnetic field (dressing field) drastically depends on polarization of the field. Namely, linear polarization results in an anisotropic gapless energy spectrum, whereas circular polarization leads to an isotropic gapped one. As a consequence, the stationary (dc) electronic transport in graphene strongly depends on parameters of the dressing field: A circularly polarized field monotonically decreases the isotropic conductivity of graphene, whereas a linearly polarized one results in both giant anisotropy of conductivity (which can reach thousands of percents) and the oscillating behavior of the conductivity as a function of the field intensity. Since the predicted phenomena can be observed in a graphene layer irradiated by a monochromatic electromagnetic wave, the elaborated theory opens a substantially new way to control electronic properties of graphene with light. PMID:26838371

  13. Dress syndrome with sepsis, acute respiratory distress syndrome and pneumomediastinum.

    PubMed

    Giri, Prabhas Prasun; Roy, Swapan; Bhattyacharya, Sukanta; Pal, Priyankar; Dhar, Sandipan

    2011-11-01

    Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome reflects a serious hypersensitivity reaction to drugs, and is characterized by skin rash, fever, lymph node enlargement, and internal organ involvement. So far, numerous drugs such as sulfonamides, phenobarbital, sulfasalazine, carbamazepine, and phenytoin have been reported to cause DRESS syndrome. We report a case of a 10-year-old girl who developed clinical manifestations of fever, rash, lymphadenopathy, hypereosinophilia, and visceral involvement (hepatitis and pneumonitis) after taking phenobarbital for seizures, with subsequent development of sepsis, acute respiratory distress syndrome (ARDS) and spontaneous air leak syndrome (pnemothorax and pneumomediastinum). She was put on steroids and various antibiotics and was ventilated, but ultimately succumbed to sepsis and pulmonary complications. PMID:22345792

  14. Control of electronic transport in graphene by electromagnetic dressing

    PubMed Central

    Kristinsson, K.; Kibis, O. V.; Morina, S.; Shelykh, I. A.

    2016-01-01

    We demonstrated theoretically that the renormalization of the electron energy spectrum near the Dirac point of graphene by a strong high-frequency electromagnetic field (dressing field) drastically depends on polarization of the field. Namely, linear polarization results in an anisotropic gapless energy spectrum, whereas circular polarization leads to an isotropic gapped one. As a consequence, the stationary (dc) electronic transport in graphene strongly depends on parameters of the dressing field: A circularly polarized field monotonically decreases the isotropic conductivity of graphene, whereas a linearly polarized one results in both giant anisotropy of conductivity (which can reach thousands of percents) and the oscillating behavior of the conductivity as a function of the field intensity. Since the predicted phenomena can be observed in a graphene layer irradiated by a monochromatic electromagnetic wave, the elaborated theory opens a substantially new way to control electronic properties of graphene with light. PMID:26838371

  15. Preparation and evaluation of biocomposites as wound dressing material.

    PubMed

    Ramnath, V; Sekar, S; Sankar, S; Sankaranarayanan, C; Sastry, T P

    2012-12-01

    Collagen was isolated from the chrome containing leather waste (CCLW) which is a major solid waste in leather industry. Composite films were made using sago starch (SG), soya protein (SY), and collagen (C) and were cross linked with glutaraldehyde (G).The films prepared were characterized for their physico chemical properties like tensile strength, infrared spectra, thermogravimetric analysis, surface morphology, and water absorption studies. Better mechanical properties and surface morphology were observed for SG-SY-G-C films compared to other films prepared using collagen. The composite films prepared were used as wound dressing material on the experimental wounds of rats and healing pattern was evaluated using planimetric, biochemical, and histopathological studies. These studies have revealed better wound healing capacity of SG-SY-G-C film and utilization of CCLW in the preparation of value added product like wound dressing material.

  16. How to perform a tracheostomy dressing and inner cannula change.

    PubMed

    Credland, Nicola

    2016-03-23

    RATIONALE AND KEY POINTS: Proactive tracheostomy management increases patient safety and reduces adverse events. ▶ A cleaning regimen performed every four hours reduces the risk of a blocked tracheostomy cannula, complete tube occlusion and respiratory arrest. ▶ Sterile tracheostomy dressings allow secretions from the stoma to be absorbed and prevent pressure damage from the tracheostomy tube. ▶ Regular dressing changes and skin inspection permit timely identification of inflammatory processes and skin excoriation, enabling prompt treatment to be instigated. REFLECTIVE ACTIVITY: Clinical skills articles can help update your practice and ensure it remains evidence based. Apply this article to your practice. Reflect on and write a short account of: 1. How this article will change your practice. 2. How you intend to develop your knowledge and skills regarding tracheostomy management. PMID:27008151

  17. Resonant scattering of surface plasmon polaritons by dressed quantum dots

    SciTech Connect

    Huang, Danhong; Cardimona, Dave; Easter, Michelle; Gumbs, Godfrey; Maradudin, A. A.; Lin, Shawn-Yu; Zhang, Xiang

    2014-06-23

    The resonant scattering of surface plasmon-polariton waves (SPP) by embedded semiconductor quantum dots above the dielectric/metal interface is explored in the strong-coupling regime. In contrast to non-resonant scattering by a localized dielectric surface defect, a strong resonant peak in the spectrum of the scattered field is predicted that is accompanied by two side valleys. The peak height depends nonlinearly on the amplitude of SPP waves, reflecting the feedback dynamics from a photon-dressed electron-hole plasma inside the quantum dots. This unique behavior in the scattered field peak strength is correlated with the occurrence of a resonant dip in the absorption spectrum of SPP waves due to the interband photon-dressing effect. Our result on the scattering of SPP waves may be experimentally observable and applied to spatially selective illumination and imaging of individual molecules.

  18. Radio-frequency dressed lattices for ultracold alkali atoms

    NASA Astrophysics Data System (ADS)

    Sinuco-León, German A.; Garraway, Barry M.

    2015-05-01

    Ultracold atomic gases in periodic potentials are powerful platforms for exploring quantum physics in regimes dominated by many-body effects as well as for developing applications that benefit from quantum mechanical effects. Further advances face a range of challenges including the realization of potentials with lattice constants smaller than optical wavelengths as well as creating schemes for effective addressing and manipulation of single sites. In this paper we propose a dressed-based scheme for creating periodic potential landscapes for ultracold alkali atoms with the capability of overcoming such difficulties. The dressed approach has the advantage of operating in a low-frequency regime where decoherence and heating effects due to spontaneous emission do not take place. These results highlight the possibilities of atom-chip technology in the future development of quantum simulations and quantum technologies, and provide a realistic scheme for starting such an exploration.

  19. Control of electronic transport in graphene by electromagnetic dressing

    NASA Astrophysics Data System (ADS)

    Kristinsson, K.; Kibis, O. V.; Morina, S.; Shelykh, I. A.

    2016-02-01

    We demonstrated theoretically that the renormalization of the electron energy spectrum near the Dirac point of graphene by a strong high-frequency electromagnetic field (dressing field) drastically depends on polarization of the field. Namely, linear polarization results in an anisotropic gapless energy spectrum, whereas circular polarization leads to an isotropic gapped one. As a consequence, the stationary (dc) electronic transport in graphene strongly depends on parameters of the dressing field: A circularly polarized field monotonically decreases the isotropic conductivity of graphene, whereas a linearly polarized one results in both giant anisotropy of conductivity (which can reach thousands of percents) and the oscillating behavior of the conductivity as a function of the field intensity. Since the predicted phenomena can be observed in a graphene layer irradiated by a monochromatic electromagnetic wave, the elaborated theory opens a substantially new way to control electronic properties of graphene with light.

  20. Hydrogel wound dressings: where do we stand in 2003?

    PubMed

    Eisenbud, David; Hunter, Heather; Kessler, Linda; Zulkowski, Karen

    2003-10-01

    Among the many categories of advanced wound dressing products available today, hydrogels are popular because they are effective, comfortable, easy to use, and cost effective. With proper use, these agents provide control of wound surface hydration, sometimes absorbing excess exudate and often providing moisture. This review describes the chemistry of hydrogels, the physiology of their interaction with the wound surface, and their role in patient care. Hydrogels have been proven effective in facilitating repair of pressure, diabetic, vascular, burn, and other wounds, and they have supplanted saline-moistened gauze for many applications. Clinical evidence suggests that no particular hydrogel is significantly more efficacious than any other, implying that other factors such as cost and ease of use may guide clinician choice of product within this class of wound dressings. PMID:14652421

  1. Control of electronic transport in graphene by electromagnetic dressing.

    PubMed

    Kristinsson, K; Kibis, O V; Morina, S; Shelykh, I A

    2016-02-03

    We demonstrated theoretically that the renormalization of the electron energy spectrum near the Dirac point of graphene by a strong high-frequency electromagnetic field (dressing field) drastically depends on polarization of the field. Namely, linear polarization results in an anisotropic gapless energy spectrum, whereas circular polarization leads to an isotropic gapped one. As a consequence, the stationary (dc) electronic transport in graphene strongly depends on parameters of the dressing field: A circularly polarized field monotonically decreases the isotropic conductivity of graphene, whereas a linearly polarized one results in both giant anisotropy of conductivity (which can reach thousands of percents) and the oscillating behavior of the conductivity as a function of the field intensity. Since the predicted phenomena can be observed in a graphene layer irradiated by a monochromatic electromagnetic wave, the elaborated theory opens a substantially new way to control electronic properties of graphene with light.

  2. Dressing up nursing diagnoses: a critical-thinking strategy.

    PubMed

    Sedlak, C A; Ludwick, R

    1996-01-01

    Teaching nursing diagnoses to beginning students who have no clinical experiences challenges educators to use their creative energies in developing strategies that facilitate students' critical-thinking skills. Dressing Up Nursing Diagnoses is a fun and creative classroom teaching strategy you can use during the Halloween season to help beginning students formulate nursing diagnoses. Two nurse educators describe their successful experiences with this unique teaching strategy. PMID:8718155

  3. Noise correlations controlled by dressed suppression and enhancement

    NASA Astrophysics Data System (ADS)

    Lan, Huayan; Ahmed, Irfan; Wang, Hang; Yang, Yiheng; Tang, Haijun; Zhang, Yiqi; Zhang, Yanpeng

    2016-08-01

    The intensity noise correlations between anti-Stokes and Stokes fields, generated from spontaneous parametric four-wave mixing (SP-FWM) process have been investigated in a ladder-type three-level system of sodium atomic vapor. By introduction of an external dressing field, the strengthened (weakened) correlations are obtained under enhancement (suppression) condition of SP-FWM. Besides, sharp correlations have been obtained as attributed to a pair of non-classical beams generated from amplified spontaneous emission.

  4. Bio-Conjugated Polycaprolactone Membranes: A Novel Wound Dressing

    PubMed Central

    Cai, Elijah Zhengyang; Teo, Erin Yiling; Jing, Lim; Koh, Yun Pei; Qian, Tan Si; Wen, Feng; Lee, James Wai Kit; Hing, Eileen Chor Hoong; Yap, Yan Lin; Lee, Hanjing; Lee, Chuen Neng; Teoh, Swee-Hin; Lim, Jane

    2014-01-01

    Background The combination of polycaprolactone and hyaluronic acid creates an ideal environment for wound healing. Hyaluronic acid maintains a moist wound environment and accelerates the in-growth of granulation tissue. Polycaprolactone has excellent mechanical strength, limits inflammation and is biocompatible. This study evaluates the safety and efficacy of bio-conjugated polycaprolactone membranes (BPM) as a wound dressing. Methods 16 New Zealand white rabbits were sedated and local anaesthesia was administered. Two 3.0×3.0 cm full-thickness wounds were created on the dorsum of each rabbit, between the lowest rib and the pelvic bone. The wounds were dressed with either BPM (n=12) or Mepitel (n=12) (control), a polyamide-silicon wound dressing. These were evaluated macroscopically on the 7th, 14th, 21st, and 28th postoperative days for granulation, re-epithelialization, infection, and wound size, and histologically for epidermal and dermal regeneration. Results Both groups showed a comparable extent of granulation and re-epithelialization. No signs of infection were observed. There was no significant difference (P>0.05) in wound size between the two groups. BPM (n=6): 8.33 cm2, 4.90 cm2, 3.12 cm2, 1.84 cm2; Mepitel (n=6): 10.29 cm2, 5.53 cm2, 3.63 cm2, 2.02 cm2; at the 7th, 14th, 21st, and 28th postoperative days. The extents of epidermal and dermal regeneration were comparable between the two groups. Conclusions BPM is comparable to Mepitel as a safe and efficacious wound dressing. PMID:25396174

  5. UrgoClean: a new dressing for desloughing exuding wounds.

    PubMed

    Kelly, Jennifer; McGrath, Alison; Wildman, Sue

    2013-06-01

    Wound debridement plays a key role in wound bed preparation and the healing of chronic wounds. A variety of techniques can be used to achieve debridement and autolytic debridement is frequently the clinician's first choice. This is aided by dressings including hydrogels and hydrocolloids, which provide the moist environment required for white blood cells to function. This product focus uses 12 case studies to examine the effectiveness of UrgoClean in wound debridement. PMID:24156171

  6. Use of Transparent Film Dressing for Dermoscopy of Mucosal Lesions.

    PubMed

    Sorrell, Jennifer; Lauren, Christine T

    2016-01-01

    Genital and mucosal nevi are not uncommonly encountered in children. These type of nevi highlight challenges in performing a thorough dermoscopic examination. Contact dermoscopy can provide additional information about a nevus that non-contact dermoscopy cannot. We propose applying a sterile transparent film dressing over the dermatoscope to act as a waterproof barrier that is also impermeable to bacteria and viruses. This provides a sanitary way to evaluate nevi in genital skin as well as on other mucosal surfaces. PMID:26250593

  7. [Biophysical properties of membrane dressing made of bacterial cellulose].

    PubMed

    Slezak, Andrzej; Jasik-Slezak, Jolanta; Kucharzewski, Marek

    2005-01-01

    In the paper, review of papers devoted to biophysical properties of membrane dressing made of bacterial cellulose was done. These properties were determined on the basis of studies on osmotic and diffusive transport through pure (non modified) bacterial cellulose membrane form called Bio-Fill. The measures of these properties are values of membrane transport parameters resulted from Kedem-Katchalsky's theory and interferograms of near-membrane regions made laser interferometric method.

  8. A Preliminary Study on Dressing Patterns and Incidence of Candidiasis

    PubMed Central

    Elegbe, Isaac A.; Botu, Modupe

    1982-01-01

    The incidence of candidiasis in two groups of voluntary participants wearing tight and loose fitted dresses was investigated by both microscopic and cultural techniques for a period of two months. Two-thirds of the positives by stain and culture were recovered from those wearing tight clothing (P < 0.05). The findings suggest that tight clothing can predispose the wearer to candidiasis, an organism that can cause vaginitis. (Am J Public Health 1982; 72:176-177.) PMID:7034553

  9. Improved collagen bilayer dressing for the controlled release of drugs.

    PubMed

    Sripriya, Ramasamy; Kumar, Muthusamy Senthil; Sehgal, Praveen Kumar

    2004-08-15

    A novel bilayer dressing has been developed from bovine succinylated collagen. The dressing contains an antibiotic, Ciprofloxacin, for both immediate and time-regulated release for controlling the infection, as the infected open wounds need special care. The dressing consists of a sponge and a film, both prepared from succinylated bovine collagen. The sponge has a smooth surface on one side; its rough surface on the other side forms the bilayer system with the film. Both sponge and film act as an anionic reservoir to hold the cationic Ciprofloxacin. The drug, after dispersing in poly (N-vinyl-2-pyrrolidione) (PVP) solution is allowed to spread in the bilayer system by diffusion. The drug stays in the bilayer system because of ionic binding, but starts releasing when comes in contact with the wound. Release of the drug is immediate, but it is regulated by ionic binding between the drug and succinylated collagen. The wound exudates, and there is a polarity-controlled release of the drug from the bilayer system. The PVP and bilayer system permits only time-regulated release, and the system lasts up to 5 days with therapeutically sufficient drug availability.

  10. Fabrication and characterization of ovalbumin films for wound dressing applications.

    PubMed

    Shojaee, Mozhgan; Navaee, Fatemeh; Jalili-Firoozinezhad, Sasan; Faturechi, Rahim; Majidi, Mohammad; Bonakdar, Shahin

    2015-03-01

    A great number of people suffer from burning injuries all around the world each year. Applying an appropriate wound dressing can promote new tissue formation, prevent losing water and inhibit invasion of infectious organisms. In this study, egg white with a long standing history, as a homemade remedy, was fabricated as a wound dressing for burn injuries. For this reason, ovalbumin films were cross-linked by 1-ethyl-3-3-dimethyl aminopropyl carbodiimide hydrochloride (EDC) with different concentrations (1, 5 and 10mM) using three concentrations of ethanol. Physical-chemical characterizations including Fourier transform infrared spectroscopy (FTIR), gas transmission rate (GTR), tensile mechanical tests, water uptake and degradation rate were performed on the samples. The sample with 5mM crosslinking agent at 70% ethanol was considered as the optimized one with 417kPa of ultimate tensile strength, 64% elongation at break and 230% water uptake. In addition, biological evaluations conducted by MTT and live/dead assay indicated no sign of cyto-toxicity for all the samples. Moreover, scanning electron microscopy (SEM) showed that the fibroblast cells were well spread on the sample with the formation of filopodia. In conclusion, modified ovalbumin can be applied as the base material for fabrication of wound dressing and skin care products.

  11. Malignant wound management: what dressings do nurses use?

    PubMed

    Wilkes, L; White, K; Smeal, T; Beale, B

    2001-03-01

    This paper reports on the findings from the first part of a three-phase project that aimed to identify nursing strategies used in the management of malignant wounds. The difficulties relating to the management of these wounds and the significant physical and psychological impact on patients are described. A quantitative postal survey aiming to identify the types of dressing used in the care of malignant wounds was sent to specialist nurses working in oncology and palliative care in New South Wales, Australia. Additional qualitative data showed that the major issues were coping with odour and meeting the financial costs of the dressing products. The long list of products compiled for this research demonstrates the complexities nurses face when selecting dressings for the management of malignant wounds. Furthermore, there are no clear recommendations to guide nursing practice. This study provides a framework for subsequent phases of the project and will hopefully lead to the development of guidelines for best practice in malignant wound management.

  12. DRESS syndrome associated with type 2 diabetes in a child

    PubMed Central

    Erdem, Semiha Bahceci; Bag, Ozlem; Karkiner, Canan Sule Unsal; Korkmaz, Huseyin Anil; Can, Demet

    2016-01-01

    Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is an uncommon, life-threatening drug reaction. The basic findings are skin rash, multiorgan involvement, and eosinophilia. Most of the aromatic anticonvulsants, such as phenytoin, phenobarbital and carbamazepine can induce DRESS. Herein we report a 14-year-old patient with DRESS syndrome related to carbamazepine use. The patient presented with signs of involvement of the skin, lungs, liver, and microscopic hematuria. Carbamazepine treatment was discontinued; antihistamines and steroids were started. Hyperglycemia, commencing on the first dose of the steroid given, persisted even after the discontinuation of steroids and improvement of other signs. There were no signs of pancreatitis or type 1 diabetes clinically in laboratory tests. Her blood glucose levels were regulated at first with insulin and later with metformin. Within 1 year of follow-up, still regulated with oral antidiabetics, she has been diagnosed with type 2 diabetes. Formerly, long-term sequelae related to “drug rash with eosinophilia and systemic symptoms syndrome” such as hepatic and renal failure, type 1 diabetes mellitus, Grave's disease, autoimmune hemolytic anemia, and lupus have also been reported. However, up to date, no cases with type 2 diabetes have been reported as long-term sequelae. To our knowledge, this is the first case in the literature presenting with type 2 diabetes as long-term sequelae. PMID:26862317

  13. Seed dressing pesticides on springtails in two ecotoxicological laboratory tests.

    PubMed

    Alves, Paulo Roger L; Cardoso, Elke J B N; Martines, Alexandre M; Sousa, José Paulo; Pasini, Amarildo

    2014-07-01

    Terrestrial ecotoxicological tests are powerful tools for assessing the ecological risks that pesticides pose to soil invertebrates, but they are rarely used to evaluate seed dressing pesticides. This study investigated the effects of seed dressing pesticides on survival and reproduction of Folsomia candida (Collembola), using standardized ecotoxicological tests (after ISO guidelines with few adaptations for tropical conditions). Commercial formulations of five seed dressing pesticides were tested individually in Tropical Artificial Soil (TAS): the insecticides imidacloprid, fipronil, thiametoxam, and the fungicides captan and carboxin+thiram. Thiametoxam, captan, and carboxin+thiram were only lethal to F. candida at the highest concentration tested (1000mg of active ingredient kg(-1) of dry soil). Imidacloprid and fipronil were lethal at lower concentrations (100 and 10mg a.i. kg(-1) soil d.w, respectively), however, these concentrations were much higher than those predicted (PEC) for soil. Imidacloprid and fipronil were the most toxic pesticides in both tests, reducing significantly collembolan reproduction (EC20=0.02 and 0.12mga.i.kg(-1) soil d.w, respectively). Further studies under more realistic conditions are needed, since imidacloprid and fipronil reduced collembolan reproduction at concentrations below or close to their respective PECs.

  14. A multicentred cohort evaluation of a chitosan gelling fibre dressing.

    PubMed

    Mason, Sue; Clarke, Caroline

    A multicentre cohort evaluation was undertaken by 15 clinicans in 11 centres across Staffordshire community care on chitosan gelling fibre dressing (Kytocel(®)). The aim of this evaluation was to examine whether the new fibre dressing improved healing outcomes for patients with chronic non-healing wounds of 6 weeks or more, observations were made regarding tissue type, fluid handling, haemostasis in bleeding friable wounds and increased granulation. Quality of life observations regarding leaking, strikethrough, pain, wear time and malodour were observed over a 4-week period or until healed. A total of 18 patients took part; 13 women and 5 men, with a mean age of 60.7 years. Fifteen (83%) had wounds in excess of 12 weeks and nine (50%) received care within wound clinics compared to home visits. Eleven (61%) patients' wounds healed within 4 weeks. A number of quality-of-life issues were addressed successfully, namely reduction in malodour and fluid handling. Sixteen (89%) rated the dressing's overall performance as very good to good. PMID:26419713

  15. Seed dressing pesticides on springtails in two ecotoxicological laboratory tests.

    PubMed

    Alves, Paulo Roger L; Cardoso, Elke J B N; Martines, Alexandre M; Sousa, José Paulo; Pasini, Amarildo

    2014-07-01

    Terrestrial ecotoxicological tests are powerful tools for assessing the ecological risks that pesticides pose to soil invertebrates, but they are rarely used to evaluate seed dressing pesticides. This study investigated the effects of seed dressing pesticides on survival and reproduction of Folsomia candida (Collembola), using standardized ecotoxicological tests (after ISO guidelines with few adaptations for tropical conditions). Commercial formulations of five seed dressing pesticides were tested individually in Tropical Artificial Soil (TAS): the insecticides imidacloprid, fipronil, thiametoxam, and the fungicides captan and carboxin+thiram. Thiametoxam, captan, and carboxin+thiram were only lethal to F. candida at the highest concentration tested (1000mg of active ingredient kg(-1) of dry soil). Imidacloprid and fipronil were lethal at lower concentrations (100 and 10mg a.i. kg(-1) soil d.w, respectively), however, these concentrations were much higher than those predicted (PEC) for soil. Imidacloprid and fipronil were the most toxic pesticides in both tests, reducing significantly collembolan reproduction (EC20=0.02 and 0.12mga.i.kg(-1) soil d.w, respectively). Further studies under more realistic conditions are needed, since imidacloprid and fipronil reduced collembolan reproduction at concentrations below or close to their respective PECs. PMID:24785712

  16. A Dressed Atom Description of the Bichromatic Force

    NASA Astrophysics Data System (ADS)

    Yatsenko, Leonid; Metcalf, Harold

    2004-05-01

    We have elaborated on the dressed atom description of the bichromatic force initially proposed by Grimm et al(R. Grimm et al., Opt. Lett. 19), 658 (1994).^,(R. Grimm et al., Proceeding of the International School of Physics, ``Enrico Fermi", Course CXXXI, IOS Press, Amsterdam 1996.). We present two completely equivalent Floquet Hamiltonians that mimic the ``atom plus field" system of the dressed atom spectrum. One is best for high velocities and the other for small velocities (kv relative to 2δ, the bichromatic frequency difference). Then we argue that the force arises from the exchange of kinetic energy with the ``atom plus field" system. But transitions between the dressed states must occur by Landau-Zener (LZ) transitions as the atoms pass through exact or small crossings, and calculate these rates from the eigenstates of the Floquet Hamiltonian. We find that some ``anti-crossings" are passed adiabatically and some non-adiabatically, and the criterion is the atomic velocity. We find two LZ velocities that bound the range of the force, thus enabling a description of its velocity range. This is the first time that the observed capture range ± δ/2k has been calculated.

  17. Molecular mechanisms of enhanced wound healing by copper oxide-impregnated dressings.

    PubMed

    Borkow, Gadi; Gabbay, Jeffrey; Dardik, Rima; Eidelman, Arthur I; Lavie, Yossi; Grunfeld, Yona; Ikher, Sergey; Huszar, Monica; Zatcoff, Richard C; Marikovsky, Moshe

    2010-01-01

    ABSTRACT Copper plays a key role in angiogenesis and in the synthesis and stabilization of extracellular matrix skin proteins, which are critical processes of skin formation. We hypothesized that introducing copper into wound dressings would enhance wound repair. Application of wound dressings containing copper oxide to wounds inflicted in genetically engineered diabetic mice (C57BL/KsOlaHsd-Lepr(db)) resulted in increased gene and in situ up-regulation of proangiogenic factors (e.g., placental growth factor, hypoxia-inducible factor-1 alpha, and vascular endothelial growth factor), increased blood vessel formation (p<0.05), and enhanced wound closure (p<0.01) as compared with control dressings (without copper) or commercial wound dressings containing silver. This study proves the capacity of copper oxide-containing wound dressings to enhance wound healing and sheds light onto the molecular mechanisms by which copper oxide-impregnated dressings stimulate wound healing. PMID:20409151

  18. Gauze vs. plastic for peripheral intravenous dressings: testing a new technology.

    PubMed

    Littenberg, B; Thompson, L

    1987-01-01

    The authors conducted a randomized, prospective, controlled trial of three different dressings for peripheral intravenous catheters in 301 acutely ill medical inpatients. Catheters were dressed with dry clean gauze or one of two brands of transparent plastic. The gauze dressings remained in place significantly longer (47 hours median) than either Uniflex (39 hours) of Tegaderm (32 hours) transparent plastic dressings (p = 0.026). Catheters were removed for complications (inflammation, mechanical failure, or infiltration) in 35% of the gauze group, compared with 58% of the Uniflex group and 48% of the Tegaderm group (p = 0.015). Not only were inflamed venipuncture sites seen less often with gauze, inflammation occurred later (p = 0.002) and with lesser severity. Dry gauze dressings resulted in longer catheter life, lower complication rates, and less expense than transparent plastic dressings for peripheral intravenous catheters.

  19. Preparation and characterization of antimicrobial wound dressings based on silver, gellan, PVA and borax.

    PubMed

    Cencetti, C; Bellini, D; Pavesio, A; Senigaglia, D; Passariello, C; Virga, A; Matricardi, P

    2012-10-15

    Silver-loaded dressings are designed to provide the same antimicrobial activity of topical silver, with the advantages of a sustained silver release and a reduced number of dressing changes. Moreover, such type of dressing must provide a moist environment, avoiding fiber shedding, dehydration and adherence to the wound site. Here we describe the preparation of a novel silver-loaded dressing based on a Gellan/Hyaff(®) (Ge-H) non woven, treated with a polyvinyl alcohol (PVA)/borax system capable to enhance the entrapment of silver in the dressing and to modulate its release. The new hydrophilic non woven dressings show enhanced water uptake capability and slow dehydration rates. A sustained silver release is also achieved. The antibacterial activity was confirmed on Staphylococcus aureus and Pseudomonas aeruginosa. PMID:22939352

  20. Preparation and characterization of antimicrobial wound dressings based on silver, gellan, PVA and borax.

    PubMed

    Cencetti, C; Bellini, D; Pavesio, A; Senigaglia, D; Passariello, C; Virga, A; Matricardi, P

    2012-10-15

    Silver-loaded dressings are designed to provide the same antimicrobial activity of topical silver, with the advantages of a sustained silver release and a reduced number of dressing changes. Moreover, such type of dressing must provide a moist environment, avoiding fiber shedding, dehydration and adherence to the wound site. Here we describe the preparation of a novel silver-loaded dressing based on a Gellan/Hyaff(®) (Ge-H) non woven, treated with a polyvinyl alcohol (PVA)/borax system capable to enhance the entrapment of silver in the dressing and to modulate its release. The new hydrophilic non woven dressings show enhanced water uptake capability and slow dehydration rates. A sustained silver release is also achieved. The antibacterial activity was confirmed on Staphylococcus aureus and Pseudomonas aeruginosa.

  1. Physical and biological assessments of the innovative bilayered wound dressing made of silk and gelatin for clinical applications.

    PubMed

    Hasatsri, Sukhontha; Yamdech, Rungnapha; Chanvorachote, Pithi; Aramwit, Pornanong

    2015-04-01

    The physical and biological assessments of the innovative bilayered wound dressing made of silk and gelatin that we have developed previously were performed to evaluate its efficacy for clinical applications. The absorption ability and dehydration rate of the dressing were assessed using the split-thickness skin graft and leg ulcer wound bed models. The bioactivities of the bilayered wound dressing were evaluated. The bilayered dressing showed continuous absorption rate of wound exudate, providing the suitability for the wound with extended inflammation phase. The dehydration rate of the bilayered dressing was comparable to the commercially available dressing of which the moisture maintenance capability is claimed. The bilayered dressing showed good conformability, as can be seen by the homogeneous distribution pattern of bromophenol blue absorbed. In terms of biological activities, the bilayered dressing was less toxic to skin cells than the commercially available dressing. The bilayered dressing was also shown to promote cell migration and collagen production due to the bioactive protein components. We here concluded that the superior properties of the bilayered dressing over the commercially available dressing were the conformability and biological activities to accelerate the wound healing, while the other properties were comparable to those of commercially available dressing. The data obtained in this study would be very useful for the further evaluation of the bilayered dressing in clinical trial.

  2. Minocycline-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome with persistent myocarditis.

    PubMed

    Shaughnessy, Kerry K; Bouchard, Susan M; Mohr, Melinda R; Herre, John M; Salkey, Kimberly S

    2010-02-01

    Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare serious adverse effect associated with a variety of medications. We present a case of minocycline-induced DRESS syndrome, which resulted in acute renal failure, transient thyroiditis, and transaminitis, and a persistent lymphocytic myocarditis resulting in congestive heart failure. To our knowledge, this is the third reported case of minocycline-induced myocarditis. Additionally, we report successful plasmapheresis and rituximab treatment for minocycline-induced myocarditis associated with the DRESS syndrome.

  3. A comparison of strength for two continuous peripheral nerve block catheter dressings

    PubMed Central

    Borg, Lindsay; Howard, Steven K.; Kim, T. Edward; Steffel, Lauren; Shum, Cynthia

    2016-01-01

    Background Despite the benefits of continuous peripheral nerve blocks, catheter dislodgment remains a major problem, especially in the ambulatory setting. However, catheter dressing techniques to prevent such dislodgment have not been studied rigorously. We designed this simulation study to test the strength of two commercially available catheter dressings. Methods Using a cadaver model, we randomly assigned 20 trials to one of two dressing techniques applied to the lateral thigh: 1) clear adhesive dressing alone, or 2) clear adhesive dressing with an anchoring device. Using a digital luggage scale attached to a loop secured by the dressing, the same investigator applied steadily increasing force with a downward trajectory towards the floor until the dressing was removed or otherwise disrupted. Results The weight, measured (median [10th–90th percentile]) at the time of dressing disruption or removal, was 1.5 kg (1.3–1.8 kg) with no anchoring device versus 4.9 kg (3.7–6.5 kg) when the dressing included an anchoring device (P < 0.001). Conclusions Based on this simulation study, using an anchoring device may help prevent perineural catheter dislodgement and therefore premature disruption of continuous nerve block analgesia.

  4. Severe acute hepatitis in the DRESS syndrome: Report of two cases.

    PubMed

    Lens, Sabela; Crespo, Gonzalo; Carrión, Jose A; Miquel, Rosa; Navasa, Miquel

    2010-01-01

    The DRESS (drug rash, eosinophilia and systemic symptoms) syndrome, also known as DIHS (drug-induced hypersensitivity syndrome), is a severe idiosyncratic reaction to several drugs, mainly antiepileptics and antibiotics, which can occasionally produce acute liver failure. In this article we present two cases of the DRESS syndrome presenting with severe acute hepatitis, including the first case of DRESS associated with levetiracetam. Although both cases finally resolved with good outcomes, DRESS can lead to acute liver failure and has a bad prognosis when liver damage is present. Rapid diagnosis is crucial since withdrawal of the offending drug is the key of treatment, while the potential role of corticosteroids is discussed. PMID:20526017

  5. Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilm development

    NASA Astrophysics Data System (ADS)

    Anghel, Ion; Holban, Alina Maria; Grumezescu, Alexandru Mihai; Andronescu, Ecaterina; Ficai, Anton; Anghel, Alina Georgiana; Maganu, Maria; Lazǎr, Veronica; Chifiriuc, Mariana Carmen

    2012-12-01

    This paper reports a newly fabricated nanophyto-modified wound dressing with microbicidal and anti-adherence properties. Nanofluid-based magnetite doped with eugenol or limonene was used to fabricate modified wound dressings. Nanostructure coated materials were characterized by TEM, XRD, and FT-IR. For the quantitative measurement of biofilm-embedded microbial cells, a culture-based method for viable cell count was used. The optimized textile dressing samples proved to be more resistant to staphylococcal and pseudomonal colonization and biofilm formation compared to the uncoated controls. The functionalized surfaces for wound dressing seems to be a very useful tool for the prevention of wound microbial contamination on viable tissues.

  6. An innovative bi-layered wound dressing made of silk and gelatin for accelerated wound healing.

    PubMed

    Kanokpanont, Sorada; Damrongsakkul, Siriporn; Ratanavaraporn, Juthamas; Aramwit, Pornanong

    2012-10-15

    In this study, the novel silk fibroin-based bi-layered wound dressing was developed. Wax-coated silk fibroin woven fabric was introduced as a non-adhesive layer while the sponge made of sericin and glutaraldehyde-crosslinked silk fibroin/gelatin was fabricated as a bioactive layer. Wax-coated silk fibroin fabrics showed improved mechanical properties compared with the non-coated fabrics, but less adhesive than the commercial wound dressing mesh. This confirmed by results of peel test on both the partial- and full-thickness wounds. The sericin-silk fibroin/gelatin spongy bioactive layers showed homogeneous porous structure and controllable biodegradation depending on the degree of crosslinking. The bi-layered wound dressings supported the attachment and proliferation of L929 mouse fibroblasts, particularly for the silk fibroin/gelatin ratio of 20/80 and 0.02% GA crosslinked. Furthermore, we proved that the bi-layered wound dressings promoted wound healing in full-thickness wounds, comparing with the clinically used wound dressing. The wounds treated with the bi-layered wound dressings showed the greater extent of wound size reduction, epithelialization, and collagen formation. The superior properties of the silk fibroin-based bi-layered wound dressings compared with those of the clinically used wound dressings were less adhesive and had improved biological functions to promote cell activities and wound healing. This novel bi-layered wound dressing should be a good candidate for the healing of full-thickness wounds.

  7. Colloidal silver-based nanogel as nonocclusive dressing for multiple superficial pellet wounds.

    PubMed

    Dharmshaktu, Ganesh Singh; Singhal, Aanshu; Pangtey, Tanuja

    2016-01-01

    A good dressing is mandatory to an uncomplicated wound healing, especially when foreign particles contaminate the wound. Various forms of dressing preparations are available for use and differ in chemical composition and efficacy. Silver has been a known agent with good antimicrobial and healing properties and recent times has seen an upsurge in various silver-based dressing supplements. We describe our report of use and efficacy of a silver nanoparticle- based gel dressing in the healing of multiple superficial firearm pellet wounds. PMID:27453869

  8. Treating skin tears in nursing home residents: a pilot study comparing four types of dressings.

    PubMed

    Edwards, H; Gaskill, D; Nash, R

    1998-03-01

    A pilot study was conducted to compare four types of dressings used to treat skin tears in nursing home residents. Wounds treated with a non-occlusive dressing healed more quickly than those dressed with occlusive dressings. The results suggest that ease of use and product wastage are important considerations when treating skin tears. The pilot study also highlights the need for further research into skin tear management and the need for ongoing education for nurses regarding skin integrity risk assessment and product information.

  9. Magnetoelectronic properties of graphene dressed by a high-frequency field

    NASA Astrophysics Data System (ADS)

    Kibis, O. V.; Morina, S.; Dini, K.; Shelykh, I. A.

    2016-03-01

    Solving the Schrödinger problem for electrons in graphene subjected to both a stationary magnetic field and a strong high-frequency electromagnetic wave (dressing field), we found that the dressing field drastically changes the structure of Landau levels in graphene. As a consequence, the magnetoelectronic properties of graphene are very sensitive to the dressing field. Particularly, it is demonstrated theoretically that the dressing field strongly changes the optical spectra and the Shubnikov-de Haas oscillations. As a result, the developed theory opens a way for controlling magnetoelectronic properties of graphene with light.

  10. Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilm development.

    PubMed

    Anghel, Ion; Holban, Alina Maria; Grumezescu, Alexandru Mihai; Andronescu, Ecaterina; Ficai, Anton; Anghel, Alina Georgiana; Maganu, Maria; Laz R, Veronica; Chifiriuc, Mariana Carmen

    2012-01-01

    This paper reports a newly fabricated nanophyto-modified wound dressing with microbicidal and anti-adherence properties. Nanofluid-based magnetite doped with eugenol or limonene was used to fabricate modified wound dressings. Nanostructure coated materials were characterized by TEM, XRD, and FT-IR. For the quantitative measurement of biofilm-embedded microbial cells, a culture-based method for viable cell count was used. The optimized textile dressing samples proved to be more resistant to staphylococcal and pseudomonal colonization and biofilm formation compared to the uncoated controls. The functionalized surfaces for wound dressing seems to be a very useful tool for the prevention of wound microbial contamination on viable tissues.

  11. A comparison of an opaque foam dressing versus a transparent film dressing in the management of skin tears in institutionalized subjects.

    PubMed

    Thomas, D R; Goode, P S; LaMaster, K; Tennyson, T; Parnell, L K

    1999-06-01

    Epidemiological studies suggest that at least 1.5 million skin tears occur each year in institutionalized adults. Despite this incidence, very little is known about the management of skin tears in elderly persons. Studies related to wound dressings and healing rates for these skin tears have rarely been reported in the medical literature. A randomized, prospective trial of 37 subjects compared the treatment of skin tears using either an opaque foam dressing or a transparent film dressing. Subjects had either a modified Payne-Martin Category II (25%-75% epidermal loss) or Category III (100% epidermal loss) skin tear. Category I skin tears (linear with no tissue loss) and skin tears greater than 48 hours old were excluded. Mean subject age was 85.1 +/- 9.7 years. Subjects were followed weekly until healed or for up to 21 days. Subjects in the comparison groups did not differ at baseline in age, sex, wound severity score, presence of diabetes, nutrition score, ambulation and mobility score, or mental status score. Complete healing occurred in 94% (16/17) of subjects treated with the foam dressing as opposed to 65% (11/17) of subjects treated with the film dressing (P < 0.05). Complete healing correlated only with dressing type (P < 0.05) and age (P < 0.01). No other factor was associated with the healing outcome. The number of dressing changes was similar in each group, 3.1 +/- 1.2 versus 3.4 +/- 1.1. Based on the results of this study, we conclude that this opaque foam dressing is a superior wound dressing for skin tears.

  12. The design, characteristics, and application of polyurethane dressings using the electrospinning process

    NASA Astrophysics Data System (ADS)

    Kampeerapappun, Piyaporn

    In general, a dressing is used to protect and help heal wounds. There are several types of dressings on the market such as hydrocolloid, hydrogel, and medicated dressings. One technique for making a dressing is electrospinning, which is a very simple procedure used to produce fibers. Due to much smaller fiber-diameters than produced with the conventional technique, the fibers from electrospinning have unique properties: high porosity and high surface areas, which are advantageous for wound healing. In this research, the fibers were electrospun using polyurethane, TecophilicRTM or TecoflexRTM, with various additives. First, multilayer transdermal electrospun dressings, four and five-layers, were developed that allowed for the controlled release of nitric oxide (NO) from a NO2 -/ascorbic acid system encapsulated in polymer nanofibers. The amount of NO released from each wound dressing was investigated. Both the four and five-layer dressings were tested for morphology of fibers, water absorption, nitrite distribution, NO release profile after sterilization by gamma radiation, and stability. In the case of the four-layer transdermal dressing, the dressing was tested in diabetic, periodontal, and cutaneous leishmaniasis patients. Furthermore, the color change of dressing was investigated. TecophilicRTM was also spun with an antimicrobial agent, which was added to the TecophilicRTM solution to electrospin an antimicrobial dressing. The morphology of fibers was tested using an optical microscope and the water absorption, uniformity, and percent extraction of dressing were also determined. In addition, the efficiency of the antimicrobial agent in the dressing was determined according to SN 195920-1994 and ASTM 2149-01. Another NO-releasing dressing was developed employing the NO donor molecules, sodium salt of linear polyethylenimine NONOates (LPEINO-Na) and calcium salt of linear polyethylenimine NONOates (LPEINO-Ca), which were electrospun with TecophilicRTM. The NO

  13. Antimicrobial activity of silver-containing dressings on wound microorganisms using an in vitro biofilm model.

    PubMed

    Percival, Steven L; Bowler, Phillip G; Dolman, Jayne

    2007-06-01

    Antimicrobial dressings such as those containing silver are now being used widely to control wound bioburden, and tests to demonstrate their efficacy predominantly involve in vitro models using free-living or planktonic bacteria. In this present study a wide range of antibiotic-sensitive and resistant bacteria were tested in their quasi-sessile state using a standard agar assay and a second method used a poloxamer gel (true biofilm state - poloxamer encourages microorganisms to exhibit a more clinically relevant biofilm phenotype) technique. The antimicrobial activity of two silver dressings, a silver-containing Hydrofiber (SCH) dressing and a nanocrystalline silver-containing dressing (NCS), were evaluated on a variety of microorganisms, using a zone-of-inhibition (ZOI) test. When grown on agar (presenting a quasi-sessile state of each organism), the antibiotic-susceptible microorganisms were generally more susceptible to the SCH dressing compared with the NCS. ZOIs associated with SCH dressing ranged between 5.7 and 17.5 mm; those for the NCS against the same group of organisms ranged between 1.9 and 8.6 mm. When grown on poloxamer gel, (presenting the biofilm state of each organism) the same group of microorganisms were less susceptible to both dressings. The SCH dressing was most effective against strains of Pseudomonas aeruginosa, Candida albicans and Staphylococcus aureus (ZOI range: 2.6-6 mm); the NCS was most effective against strains of Klebsiella pneumoniae, Enterococcus faecalis and Escherichia coli (i.e. ZOI range: 1-2.8 mm). Similarly to the antibiotic-susceptible microorganisms, nine of ten antibiotic-resistant bacterial strains when grown on agar were more susceptible to the SCH dressing compared with the NCS. Although the microorganisms tested were universally less susceptible to the silver dressings when in their biofilm state, in the majority of cases, the SCH dressing demonstrated greater biofilm-inhibiting activity than the NCS.

  14. RF-dressed Rydberg atoms in hollow-core fibres

    NASA Astrophysics Data System (ADS)

    Veit, C.; Epple, G.; Kübler, H.; Euser, T. G.; Russell, P. St. J.; Löw, R.

    2016-07-01

    The giant electro-optical response of Rydberg atoms manifests itself in the emergence of sidebands in the Rydberg excitation spectrum if the atom is exposed to a radio-frequency (RF) electric field. Here we report on the study of RF-dressed Rydberg atoms inside hollow-core photonic crystal fibres, a system that enables the use of low modulation voltages and offers the prospect of miniaturised vapour-based electro-optical devices. Narrow spectroscopic features caused by the RF field are observed for modulation frequencies up to 500 MHz.

  15. An(1) Toda solitons and the dressing symmetry

    NASA Astrophysics Data System (ADS)

    Belich, H.; Paunov, R.

    1997-08-01

    We present an elementary derivation of the solitonlike solutions in the An(1) Toda models which is an alternative to the previously used Hirota method. The solutions of the underlying linear problem corresponding to the N-solitons are calculated. This enables us to obtain explicit expression for the element which, by dressing group action, produces a generic soliton solution. In the particular example of monosolitons we suggest a relation to the vertex operator formalism, previously used by Olive, Turok, and Underwood. Our results can also be considered as generalization of the approach to the sine-Gordon solitons, proposed by Babelon and Bernard.

  16. Nonlinear dressed states at the miscibility-immiscibility threshold

    NASA Astrophysics Data System (ADS)

    Nicklas, E.; Muessel, W.; Strobel, H.; Kevrekidis, P. G.; Oberthaler, M. K.

    2015-11-01

    The dynamical evolution of spatial patterns in a complex system can reveal the underlying structure and stability of stationary states. As a model system we employ a two-component Bose-Einstein condensate at the transition from miscible to immiscible with the additional control of linear interconversion. Excellent agreement is found between the detailed experimental time evolution and the corresponding numerical mean-field computations. Analyzing the dynamics of the system, we find clear indications of stationary states that we term nonlinear dressed states. A steady-state bifurcation analysis reveals a smooth connection of these states with dark-bright soliton solutions of the integrable two-component Manakov model.

  17. Surgical dressings and turbulent years of cotton industry.

    PubMed

    Stephens-Borg, Keith

    2008-07-01

    Everyday use of a simple cotton bud should remind us of our not so distant past and of the appalling trade in people. Harvesting this precious commodity required forced labour eventually leading to a key turning point in the history of surgery, as civil war raged in America during the 1860s. The fight to end slavery was to reveal a new weapon against disease and certain death. A material used in this struggle against wound infection was the available stockpiles of redundant cotton. Once boiled to make softer, its use on patients in military hospitals proved to be the first clinical application of sterile surgical dressings.

  18. Surgical dressings and turbulent years of cotton industry.

    PubMed

    Stephens-Borg, Keith

    2008-07-01

    Everyday use of a simple cotton bud should remind us of our not so distant past and of the appalling trade in people. Harvesting this precious commodity required forced labour eventually leading to a key turning point in the history of surgery, as civil war raged in America during the 1860s. The fight to end slavery was to reveal a new weapon against disease and certain death. A material used in this struggle against wound infection was the available stockpiles of redundant cotton. Once boiled to make softer, its use on patients in military hospitals proved to be the first clinical application of sterile surgical dressings. PMID:18710130

  19. Comparing the efficacies of alginate, foam, hydrocolloid, hydrofiber, and hydrogel dressings in the management of diabetic foot ulcers and venous leg ulcers: a systematic review and meta-analysis examining how to dress for success.

    PubMed

    Saco, Michael; Howe, Nicole; Nathoo, Rajiv; Cherpelis, Basil

    2016-01-01

    Diabetic foot ulcers and venous leg ulcers are chronic wounds frequently encountered by dermatologists. Choosing appropriate wound dressings can effectively promote wound healing and potentially reduce morbidity and financial burden experienced by patients. The objective of our systematic review and meta-analysis was to evaluate wound healing efficacies of synthetic active dressings in diabetic foot ulcer and venous leg ulcer management. For data collection, PubMed, Embase, Cochrane Library, CINAHL, and clinicaltrials.gov online databases were searched from database inception to 10 May 2015. Fixed and random effects modeling were used to calculate pooled risk ratios for complete ulcer healing from pairwise dressing comparisons. The results of our review showed moderate-quality level evidence that hydrogels were more effective in healing diabetic foot ulcers than basic wound contact dressings (RR 1.80 [95% CI, 1.27-2.56]). The other dressing comparisons showed no statistically significant differences between the interventions examined in terms of achieving complete diabetic foot ulcer healing. Non-adherent dressings were more cost-effective than hydrofiber dressings for diabetic foot ulcers in terms of mean total cost per patient of the dressings themselves. All venous leg ulcer pairwise dressing comparisons showed equivalent dressing efficacies in terms of promoting complete ulcer healing. Overall, most synthetic active dressings and traditional wound dressings are equally efficacious in treating diabetic foot ulcers and venous leg ulcers. For treating diabetic foot ulcers, hydrogels are more efficacious than basic wound contact dressings, and non-adherent dressings are more cost-effective than hydrofiber dressings. Ultimately, dressing choice should be tailored to the wound and the patient. PMID:27617934

  20. An Approach to Teaching Self-Dressing to a Child with Dual Sensory Impairment.

    ERIC Educational Resources Information Center

    McKelvey, Jenifer L.; And Others

    1992-01-01

    A self-help skills instructional program used graduated guidance as a method of teaching independent dressing to an 11-year-old girl with profound mental retardation, seizure disorder, deafness, and blindness. Dressing skills improved with instruction and were maintained. Task analyses are presented for putting on socks, shorts, and shirts. (JDD)

  1. Effect of Most-to-Least Prompting Procedure on Dressing Skill of Students with Autism

    ERIC Educational Resources Information Center

    Çetrez-Iscan, Galibiye; Nurçin, Elçin; Fazlioglu, Yesim

    2016-01-01

    Dressing skill is one of the necessary self-care skills that is taught to individuals with autism in order for them to be able to live independently. Typically, developing individuals can acquire dressing skill on their own; however, children with autism have difficulties in learning such skill without systematic teaching. Thus, teaching dressing…

  2. Analyzing a School Dress Code in a Junior High School: A Set of Exercises.

    ERIC Educational Resources Information Center

    East, Maurice A.; And Others

    Five exercises based on a sample school dress code were designed from a political science perspective to help students develop skills in analyzing issues. The exercises are intended to be used in five or more class periods. In the first exercise, students read a sample dress code and name groups of people who might have opinions about it. In…

  3. Prospective clinical study of a new adhesive gelling foam dressing in pressure ulcers.

    PubMed

    Parish, Lawrence Charles; Dryjski, Maciej; Cadden, Sue

    2008-03-01

    This prospective, non comparative study evaluated the safety and effectiveness of an adhesive gelling foam dressing in pressure ulcer management. Twenty-three subjects with exuding pressure ulcers were recruited from seven centres in the USA and Canada. Study treatment included an adhesive gelling foam dressing, optional tape/roll bandaging and mandatory pressure-reducing/relieving devices. Subjects were followed until ulcer healing, for up to 28 days, or on patient withdrawal from the study, whichever came first. Dressings were changed at least once every 7 days. Mean percentage change in ulcer area from baseline to final measurement was -13%. Investigators reported healing or subjective improvement of ulcer condition in 61% of patients. Mean dressing wear time was 4.2 days. Subjects found the dressing was comfortable, soothing and cushioning in situ at 80%, 64% and 70% of dressing changes, respectively. Subjects reported pain severity of none or mild for every dressing change. Fourteen subjects experienced adverse events, including seven subjects with study-related maceration, erythema, wound enlargement, blister or infection. A regimen including an adhesive gelling foam dressing proved to be safe and effective for managing exudate, protecting the surrounding skin, minimising pain and supporting healing of pressure ulcers with exudate.

  4. Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review.

    PubMed

    Moura, Liane I F; Dias, Ana M A; Carvalho, Eugénia; de Sousa, Hermínio C

    2013-07-01

    Diabetic foot ulcers (DFUs) are a chronic, non-healing complication of diabetes that lead to high hospital costs and, in extreme cases, to amputation. Diabetic neuropathy, peripheral vascular disease, abnormal cellular and cytokine/chemokine activity are among the main factors that hinder diabetic wound repair. DFUs represent a current and important challenge in the development of novel and efficient wound dressings. In general, an ideal wound dressing should provide a moist wound environment, offer protection from secondary infections, remove wound exudate and promote tissue regeneration. However, no existing dressing fulfills all the requirements associated with DFU treatment and the choice of the correct dressing depends on the wound type and stage, injury extension, patient condition and the tissues involved. Currently, there are different types of commercially available wound dressings that can be used for DFU treatment which differ on their application modes, materials, shape and on the methods employed for production. Dressing materials can include natural, modified and synthetic polymers, as well as their mixtures or combinations, processed in the form of films, foams, hydrocolloids and hydrogels. Moreover, wound dressings may be employed as medicated systems, through the delivery of healing enhancers and therapeutic substances (drugs, growth factors, peptides, stem cells and/or other bioactive substances). This work reviews the state of the art and the most recent advances in the development of wound dressings for DFU treatment. Special emphasis is given to systems employing new polymeric biomaterials, and to the latest and innovative therapeutic strategies and delivery approaches. PMID:23542233

  5. Dressing of diamond grinding wheels by abrasive water jet for freeform optical surface grinding

    NASA Astrophysics Data System (ADS)

    Wang, Wei; Yao, Peng; Li, Chengwu; Huang, Chuanzhen; Wang, Jun; Zhu, Hongtao; Liu, Zengwen

    2014-08-01

    During the ultra-precision grinding of a large aperture mirror made of RB-SiC, the grinding wheel becomes dull rapidly, which will lead to an increase of grinding force and a decrease of grinding ratio. In this paper, diamond grinding sticks were dressed with micro SiC abrasive water jet and water jet. Through single factorial experiments, the influence of jet pressure on the dressing performance was investigated. To analyze and evaluate the effect of dressing quantitatively, the 3D roughness and the wheel topography were measured and compared with laser scanning confocal microscope before and after dressing. The experimental results show that the abrasive grains are well protruded from binder and the distribution of the abrasive grains becomes uniform after dressing by abrasive water jet when the dressing parameters are properly selected. The dressing performance of abrasive water jet is much better than water jet. For dressing ultra-fine grit size wheels, the abrasive size of the jet should be smaller than the wheel grit size to achieve a better result. The jet pressure is an obvious influence factor of the surface topography.

  6. Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review.

    PubMed

    Moura, Liane I F; Dias, Ana M A; Carvalho, Eugénia; de Sousa, Hermínio C

    2013-07-01

    Diabetic foot ulcers (DFUs) are a chronic, non-healing complication of diabetes that lead to high hospital costs and, in extreme cases, to amputation. Diabetic neuropathy, peripheral vascular disease, abnormal cellular and cytokine/chemokine activity are among the main factors that hinder diabetic wound repair. DFUs represent a current and important challenge in the development of novel and efficient wound dressings. In general, an ideal wound dressing should provide a moist wound environment, offer protection from secondary infections, remove wound exudate and promote tissue regeneration. However, no existing dressing fulfills all the requirements associated with DFU treatment and the choice of the correct dressing depends on the wound type and stage, injury extension, patient condition and the tissues involved. Currently, there are different types of commercially available wound dressings that can be used for DFU treatment which differ on their application modes, materials, shape and on the methods employed for production. Dressing materials can include natural, modified and synthetic polymers, as well as their mixtures or combinations, processed in the form of films, foams, hydrocolloids and hydrogels. Moreover, wound dressings may be employed as medicated systems, through the delivery of healing enhancers and therapeutic substances (drugs, growth factors, peptides, stem cells and/or other bioactive substances). This work reviews the state of the art and the most recent advances in the development of wound dressings for DFU treatment. Special emphasis is given to systems employing new polymeric biomaterials, and to the latest and innovative therapeutic strategies and delivery approaches.

  7. Cross Dressing and Gender Dysphoria in People with Learning Disabilities: A Descriptive Study

    ERIC Educational Resources Information Center

    Parkes, Georgina; Hall, Ian; Wilson, Daniel

    2009-01-01

    We aimed to determine the characteristics of people with learning disability who cross-dress or who have gender dysphoria. Using a retrospective review of anonymised data from clinical records about people referred to a specialist service. All 13 participants cross-dressed and 12 were biological males. Only one person was in a core transsexual…

  8. Human neutrophil elastase inhibition with a novel cotton alginate wound dressing formulation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Occlusion and elasticity were combined in a novel cotton-based alginate dressing containing a non-toxic elastase inhibitor. Cotton gauzes were modified with a textile finishing process for incorporating alginate to yield a dressing material that retains elasticity while enhancing absorption. The ...

  9. The Effect of Academics' Dress and Gender on Student Perceptions of Instructor Approachability and Likeability

    ERIC Educational Resources Information Center

    Chatelain, Amber M.

    2015-01-01

    This study sought to discover student perceptions of academics' dress and gender and their impact on perceived instructor approachability and likeability. Three categories of dress were examined: casual, business casual and professional. The results of this study suggest students at career-arts institutions perceive female teachers as less…

  10. Politicas de uniformes y codigos de vestuario (Uniforms and Dress-Code Policies). ERIC Digest.

    ERIC Educational Resources Information Center

    Lumsden, Linda

    This digest in Spanish examines schools' dress-code policies and discusses the legal considerations and research findings about the effects of such changes. Most revisions to dress codes involve the use of uniforms, typically as a way to curb school violence and create a positive learning environment. A recent survey of secondary school principals…

  11. The multifunctional wound dressing with core-shell structured fibers prepared by coaxial electrospinning

    NASA Astrophysics Data System (ADS)

    Wei, Qilin; Xu, Feiyang; Xu, Xingjian; Geng, Xue; Ye, Lin; Zhang, Aiying; Feng, Zengguo

    2016-06-01

    The non-woven wound dressing with core-shell structured fibers was prepared by coaxial electrospinning. The polycaprolactone (PCL) was electrospun as the fiber's core to provide mechanical strength whereas collagen was fabricated into the shell in order to utilize its good biocompatibility. Simultaneously, the silver nanoparticles (Ag-NPs) as anti-bacterial agent were loaded in the shell whereas the vitamin A palmitate (VA) as healing-promoting drug was encapsulated in the core. Resulting from the fiber's core-shell structure, the VA released from the core and Ag-NPs present in the shell can endow the dressing both heal-promoting and anti-bacteria ability simultaneously, which can greatly enhance the dressing's clinical therapeutic effect. The dressing can maintain high swelling ratio of 190% for 3 d indicating its potential application as wet dressing. Furthermore, the dressing's anti-bacteria ability against Staphylococcus aureus was proved by in vitro anti-bacteria test. The in vitro drug release test showed the sustainable release of VA within 72 h, while the cell attachment showed L929 cells can well attach on the dressing indicating its good biocompatibility. In conclusion, the fabricated nanofibrous dressing possesses multiple functions to benefit wound healing and shows promising potential for clinical application.

  12. School Dress Code Law in the 90's: "Tinkering" with Fashion and Gangs.

    ERIC Educational Resources Information Center

    Lane, Kenneth E.; Richardson, Michael D.

    Dress codes directed at gang attire present school officials with the dilemma of ensuring the safety of the students in a school environment versus the First Amendment rights of students to express themselves. A review of some of the court decisions limited to freedom of expression and general dress code cases serves as a foundation from which to…

  13. Counterconformity: An Attribution Model of Adolescents' Uniqueness-Seeking Behaviors in Dressing

    ERIC Educational Resources Information Center

    Ling, I-Ling

    2008-01-01

    This article explores how an attribution model will illustrate uniqueness-seeking behavior in dressing in the Taiwanese adolescent subculture. The study employed 443 senior high school students. Results show that the tendency of uniqueness-seeking behavior in dressing is moderate. However, using cluster analysis to segment the counterconformity…

  14. Media Frames regarding Teacher Dress: Implications for Career and Technical Education Teacher Preparation

    ERIC Educational Resources Information Center

    Freeburg, Beth Winfrey; Workman, Jane E.

    2010-01-01

    The purpose of this study was to explore teacher dress in United States schools as presented in the newspaper. Twenty-nine articles were examined to answer three questions. Results revealed: (a) the newspaper provided four contexts for processing information about teacher dress--roles, control, impression management, and educational learning…

  15. 21 CFR 520.2380a - Thiabendazole top dressing and mineral protein block.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Thiabendazole top dressing and mineral protein... § 520.2380a Thiabendazole top dressing and mineral protein block. (a) Chemical name. 2-(4-Thiazolyl..., Ostertagia and Cooperia). (iv) Limitations. Administer to cattle on pasture or range accustomed to...

  16. 21 CFR 520.2380a - Thiabendazole top dressing and mineral protein block.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Thiabendazole top dressing and mineral protein... § 520.2380a Thiabendazole top dressing and mineral protein block. (a) Chemical name. 2-(4-Thiazolyl..., Ostertagia and Cooperia). (iv) Limitations. Administer to cattle on pasture or range accustomed to...

  17. 21 CFR 520.2380a - Thiabendazole top dressing and mineral protein block.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Thiabendazole top dressing and mineral protein... § 520.2380a Thiabendazole top dressing and mineral protein block. (a) Chemical name. 2-(4-Thiazolyl..., Ostertagia and Cooperia). (iv) Limitations. Administer to cattle on pasture or range accustomed to...

  18. 21 CFR 520.2380a - Thiabendazole top dressing and mineral protein block.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Thiabendazole top dressing and mineral protein... § 520.2380a Thiabendazole top dressing and mineral protein block. (a) Chemical name. 2-(4-Thiazolyl..., Ostertagia and Cooperia). (iv) Limitations. Administer to cattle on pasture or range accustomed to...

  19. 21 CFR 520.2380a - Thiabendazole top dressing and mineral protein block.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Thiabendazole top dressing and mineral protein... § 520.2380a Thiabendazole top dressing and mineral protein block. (a) Chemical name. 2-(4-Thiazolyl..., Ostertagia and Cooperia). (iv) Limitations. Administer to cattle on pasture or range accustomed to...

  20. The Influence of Physical Attractiveness and Dress on Campus Recruiters' Impressions of Female Job Applicants.

    ERIC Educational Resources Information Center

    Johnson, Kim K. P.; Roach-Higgins, Mary E.

    1987-01-01

    The influence of physical attractiveness, dress, and job type upon 300 college recruiters' impressions of females' employment potential was investigated. Subjects rated female applicants from a photograph on eight employment potential statements. Results indicate that the applicant's style of dress exerted a consistent influence on recruiters'…

  1. Thrombin production and human neutrophil elastase sequestration by modified cellulose dressings and their electrokinetic analysis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Hemostatic control of lethal extremity arterial hemorrhage has been addressed with a variety of dressing motifs which have included the use of widely divergent materials i.e. clay minerals, fibrin sealant, and chitosan. The rapid deployment of some of these products as combat dressings reflects the ...

  2. A budget impact analysis comparing a Hydrofiber® ; dressing to an alginate dressing in managing exuding venous leg ulcers in France.

    PubMed

    Yan, Songkai; Colin, Xavier; Coudray-Omnès, Carole; Guido-Morin, Pascale; Kommala, Dheerendra R

    2014-06-01

    An Excel model was developed to compare total costs (including primary and secondary dressings only) of Hydrofiber(®) ; dressing (2010 branded price) versus an alginate dressing (generic or branded price) in managing exuding venous leg ulcers considering mean wear time and mean duration of exudate management phase, from the French Social Security perspective over 5 years (2011-2015). Budget impact (based on prevalence of venous leg ulcers in France) was estimated as the difference between scenario 1 (Hydrofiber(®) ; versus alginate dressing usage proportion increasing slightly per year) and Scenario2 (proportion remaining at 2010 levels). Annual costs and net savings per patient for the dressings were calculated in analyses 1 and 2. Analysis 1 (28-day mean exudate management phase for both Hydrofiber(®) ; and alginate dressing groups): total costs 66·82€ Hydrofiber(®) ;, 70·08€ generic alginate, 77·0€ branded alginate; net savings 3·26€ and 10·18€ for Hydrofiber(®) ; versus generic and branded alginate. Analysis 2 (mean exudate management phase of 22·2 versus 28 days for Hydrofiber(®) ; versus alginate): total costs 52·92€, 70·08€ and 77·0€, and net savings 17·10€ and 24·02€, accordingly. Total cost savings (budget impact scenario 1 minus scenario 2): Analysis 1 - 223 107€ and 696 304€ for Hydrofiber(®) ; versus generic and branded alginate dressings, respectively; Analysis 2 - 1 169 845€ and 1 643 042€ accordingly. Sensitivity analyses indicated that results are reliable. This conservative analysis shows that effective exudate management using Hydrofiber(®) ; dressing can produce sizeable cost savings.

  3. Comfortable and leisurely: Old women on style and dress.

    PubMed

    Lövgren, Karin

    2016-01-01

    This article uses wardrobe interviews with women in the ages of 62-94 to explore transitions and continuities during the life course. During interviews the women have defined their style preferences. One categorization favored by several of them was comfortable. Different meanings were attached to this concept. Practical and convenient outfits were described as increasingly important when aging. Garments that did not expose the body-and its changes with aging-were preferred. The informants talked about the importance of feeling at ease, appropriately dressed for the occasion and situation. They were concerned with feeling nice in their outfits but also stressed becoming more laid-back and prioritizing convenience in their later years. All of these examples had to do with comfort and being comfortable. Uncomfortable clothes were too tight, deemed wrong for the occasion, and unwanted sources of self-consciousness and visibility. Transitions in their style of dress had been gradual, slowly adapting to changes in everyday life as well as in their bodies. PMID:26713964

  4. 150 patient experiences with a soft silicone foam dressing.

    PubMed

    Bateman, Sharon Dawn

    Pain, malodour and exudate from acute and chronic wounds can be catastrophic to the patient. Excessive exudate results in significant tissue damage to the wound bed and surrounding skin, reduces quality of life, and often requires costly specialist service input. Effective wound assessment and management including appropriate dressing choice is, therefore, paramount to ensure wound healing can take place in a timely manner. This observational evaluation explores 150 ward-based patients who presented with acute and chronic exuding wounds; it examines and evaluates the proposed benefits of the Cutimed(®) Siltec foam dressing range over a 4-month period in an acute hospital setting. The outcomes of the evaluation were exudate management, maceration reduction, atraumatic application and removal, non-adherence and patient experience. The evaluation highlights not only an overall positive improvement in exudate management and maceration reduction, non-adherence, atraumatic application and removal but also emphasises the importance of a positive patient experience in the wound-care journey.

  5. Elastic adhesive dressing treatment of bleeding wounds in trauma victims.

    PubMed

    Naimer, S A; Chemla, F

    2000-11-01

    Conventional methods for hemorrhage control in the trauma patient fall short of providing a full solution for the life-threatening bleeding injury. The tourniquet is limited specifically to injuries of the distal limbs. Local pressure or tight bandaging with military bandages is cumbersome and often insufficient. Therefore, we sought a superior method to stop bleeding in emergency situations. Our objective is report and description of our experience with this method. Since 1992 our trauma team repeatedly encountered multiple trauma victims presenting with bleeding wounds. We achieved hemorrhage control by means of an adhesive elastic bandage applied directly over a collection of 4 x 4 gauze pads placed on the wound surface. The roll is then wrapped around the body surface, over the bleeding site, until sufficient pressure is reached to terminate ongoing hemorrhage. Three typical cases are described in detail. Adhesive elastic dressing compression was successful in fully controlling bleeding without compromise of distal blood flow. Our method corresponded to the demand for an immediate, effective and lasting form of hemorrhage control without complications. Furthermore, this technique proved successful even over body surfaces normally recognized as difficult to compress. We experienced equal favorable success while working during transit by either ambulance or helicopter transportation. We find our preliminary experience using elastic adhesive dressing for bleeding control encouraging and suggest that this may substitute existing practices as the selected treatment when indicated. This method is presently underrecognized for this purpose. Development of a single unit bandage may further enhance success in the future.

  6. Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

    NASA Astrophysics Data System (ADS)

    Martínez-Pardo, M. E.; Ley-Chávez, E.; Reyes-Frías, M. L.; Rodríguez-Ferreyra, P.; Vázquez-Maya, L.; Salazar, M. A.

    2007-11-01

    Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is "Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation". At present, more than 150 patients from 16 hospitals have been successfully treated with these tissues. This paper presents a brief description of the tissue processing, as well as the present Mexican clinical experience with children and adult patients who underwent medical treatment with radiosterilized amnion and pig skin, used as biological wound dressings on burns and ocular surface disorders.

  7. Physically crosslinked-sacran hydrogel films for wound dressing application.

    PubMed

    Wathoni, Nasrul; Motoyama, Keiichi; Higashi, Taishi; Okajima, Maiko; Kaneko, Tatsuo; Arima, Hidetoshi

    2016-08-01

    The thin hydrogel films consisting of water-swollen polymer networks can potentially be applied for biomedical fields. Recently, natural polysaccharides have great attentions to be developed as wound healing and protection. In the present study, we newly prepared and characterized a physically crosslinked-hydrogel film composed of a novel megamolecular polysaccharide sacran for wound dressing application. We successfully fabricated a physically crosslinked-sacran hydrogel film by a solvent-casting method. The thickness of a sacran hydrogel film was lower than that of a sodium alginate (Na-alginate) film. Importantly, the swollen ratio of a sacran hydrogel film in water at 24h was 19-fold, compared to initial weight. Meanwhile, a Na-alginate hydrogel film was completely broken apart after rehydration. Moreover, a sacran hydrogel film did not show any cytotoxicity on NIH3T3 cells, a murine fibroblast cell line. The in vivo skin hydration study revealed that a sacran hydrogel film significantly increased the moisture content on hairless mice skin and considerably improved wound healing ability, compared to control (non-treated), probably due to not only the moisturing effect but also the anti-inflammatory effect of sacran. These results suggest that sacran has the potential properties as a basic biomaterial in a hydrogel film for wound dressing application. PMID:27151668

  8. Hydrocellular foam dressing increases the leptin level in wound fluid.

    PubMed

    Yoshino, Sawako; Nakagami, Gojiro; Ohira, Tomomi; Kawasaki, Rui; Shimura, Mari; Iwatsuki, Ken; Sanada, Hiromi; Kobayashi-Hattori, Kazuo; Oishi, Yuichi; Yamane, Takumi

    2015-09-01

    Hydrocellular foam dressing (HCF) absorbs excessive wound fluid, which contains various cytokines and growth factors, and ensures a moist environment to promote wound healing. However, the molecular mechanisms underlying the wound fluid component changes induced by HCF are poorly understood. In the present study, we examined the effect of HCF on wound healing and the associated regulatory mechanisms in relation to variations in cytokine levels in the wound fluid. We created full-thickness wounds on the dorsolateral skin of rats and collected the resulting wound fluid samples. HCF was immersed in a plate containing the wound fluids. HCF was then removed and the excess wound fluid remaining in the plate was examined by cytokine array and enzyme-linked immunosorbent assay. We also used a rat model and human dermal fibroblast cultures to examine the effect of wound fluid component changes during the wound healing process. Upon treatment with HCF, leptin levels were upregulated in the wound fluid. Fibroblast proliferation was enhanced and the effect was suppressed in the presence of leptin antagonist. In our in vivo model, HCF increased wound contraction compared with film dressings and this positive effect of HCF was suppressed by addition of leptin antagonist. Our results suggest that dermal fibroblast proliferation is upregulated by HCF due to increased leptin level at the wound surface, and these effects promote wound healing. We believe that the present study contributes to furthering the understanding of the mechanisms underlying the effects of HCF-induced wound healing.

  9. 150 patient experiences with a soft silicone foam dressing.

    PubMed

    Bateman, Sharon Dawn

    Pain, malodour and exudate from acute and chronic wounds can be catastrophic to the patient. Excessive exudate results in significant tissue damage to the wound bed and surrounding skin, reduces quality of life, and often requires costly specialist service input. Effective wound assessment and management including appropriate dressing choice is, therefore, paramount to ensure wound healing can take place in a timely manner. This observational evaluation explores 150 ward-based patients who presented with acute and chronic exuding wounds; it examines and evaluates the proposed benefits of the Cutimed(®) Siltec foam dressing range over a 4-month period in an acute hospital setting. The outcomes of the evaluation were exudate management, maceration reduction, atraumatic application and removal, non-adherence and patient experience. The evaluation highlights not only an overall positive improvement in exudate management and maceration reduction, non-adherence, atraumatic application and removal but also emphasises the importance of a positive patient experience in the wound-care journey. PMID:26110984

  10. Enhancing pressure ulcer prevention using wound dressings: what are the modes of action?

    PubMed

    Call, Evan; Pedersen, Justin; Bill, Brian; Black, Joyce; Alves, Paulo; Brindle, C Tod; Dealey, Carol; Santamaria, Nick; Clark, Michael

    2015-08-01

    Recent clinical research has generated interest in the use of sacral wound dressings as preventive devices for patients at risk of ulceration. This study was conducted to identify the modes of action through which dressings can add to pressure ulcer prevention, for example, shear and friction force redistribution and pressure distribution. Bench testing was performed using nine commercially available dressings. The use of dressings can reduce the amplitude of shear stress and friction reaching the skin of patients at risk. They can also effectively redirect these forces to wider areas which minimises the mechanical loads upon skeletal prominences. Dressings can redistribute pressure based upon their effective Poisson ratio and larger deflection areas, providing greater load redistribution.

  11. In vivo wound-healing effects of novel benzalkonium chloride-loaded hydrocolloid wound dressing.

    PubMed

    Jin, Sung Giu; Yousaf, Abid Mehmood; Jang, Sun Woo; Son, Mi-Won; Kim, Kyung Soo; Kim, Dong-Wuk; Li, Dong Xun; Kim, Jong Oh; Yong, Chul Soon; Choi, Han-Gon

    2015-05-01

    The purpose of this study was to evaluate the wound-healing effects of a novel benzalkonium chloride (BC)-loaded hydrocolloid wound dressing (HCD). A BC-loaded HCD was prepared with various constituents using a hot melting method, and its mechanical properties and antimicrobial activities were assessed. The in vivo wound healings of the BC-loaded HCD in various would models were evaluated in rats compared with a commercial wound dressing, Duoderm™. This BC-loaded HCD gave better skin adhesion, swelling, mechanical strength, and flexibility compared with the commercial wound dressing. It showed excellent antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. In addition, as compared with the commercial wound dressing, it showed more improved wound healings and tissue restoration effect on the excision, infection, and abrasion wounds in rats. Thus, this novel BC-loaded HCD would be an excellent alternative to the commercial wound dressing for treatment of various wounds.

  12. Efficiency of Microbial Cellulose Dressing in Partial-Thickness Burn Wounds

    PubMed Central

    Muangman, Pornprom; Opasanon, Supaporn; Suwanchot, Supaparn; Thangthed, Orapin

    2011-01-01

    Microbial cellulose is a natural polymer that can hold a quantity of water without any disconformities. Therefore, it is proposed for use as wound dressing material. We report a case of 28% total body surface area partial-thickness flame burn: approximately 4.5% superficial partial-thickness burns on anterior face and 23.5% combined superficial and deep partial-thickness burns on both upper arms and anterior trunk. A microbial cellulose dressing, Nanocell (Thai Nano Cellulose Co Ltd, Bangkok, Thailand), was applied to the face wound only once, without any further dressing change. Progress of healing, until full epithelialization on the face, was observed for 2 weeks. During the treatment period, the patient did not show any irritation or allergic reaction to this new dressing, and wound swab culture showed no evidence of bacteria presence. This innovative material can be an alternative dressing for superficial partial-thickness burn wounds. PMID:24527162

  13. Removal of adhesive wound dressing and its effects on the stratum corneum of the skin: comparison of eight different adhesive wound dressings.

    PubMed

    Matsumura, Hajime; Imai, Ryutaro; Ahmatjan, Niyaz; Ida, Yukiko; Gondo, Masahide; Shibata, Dai; Wanatabe, Katsueki

    2014-02-01

    In recent years, adhesive wound dressings have been increasingly applied postoperatively because of their ease of use as they can be kept in place without having to cut and apply surgical tapes and they can cover a wound securely. However, if a wound dressing strongly adheres to the wound, a large amount of stratum corneum is removed from the newly formed epithelium or healthy periwound skin. Various types of adhesives are used on adhesive wound dressings and the extent of skin damage depends on how much an adhesive sticks to the wound or skin surface. We quantitatively determined and compared the amount of stratum corneum removed by eight different wound dressings including polyurethane foam using acrylic adhesive, silicone-based adhesive dressing, composite hydrocolloid and self-adhesive polyurethane foam in healthy volunteers. The results showed that wound dressings with silicone adhesive and self-adhesive polyurethane foam removed less stratum corneum, whereas composite hydrocolloid and polyurethane foam using acrylic adhesive removed more stratum corneum.

  14. A model for quantitative evaluation of skin damage at adhesive wound dressing removal.

    PubMed

    Matsumura, Hajime; Ahmatjan, Niyaz; Ida, Yukiko; Imai, Ryutaro; Wanatabe, Katsueki

    2013-06-01

    The removal of adhesive wound dressings from the wound surface involves a risk of damaging the intact stratum corneum and regenerating epithelium. Pain associated with the removal of wound dressings is a major issue for patients and medical personnel. Recently, wound dressings coated with a silicone adhesive have been developed to reduce such skin damage and pain on removal and they have received good evaluation in various clinical settings. However, there is neither a standard method to quantify whether or not the integrity of the stratum corneum and regenerating epithelium is retained or if both structures are damaged by the removal of wound dressings, nor are there standardised values with which to assess skin damage. We applied six different types of adhesive wound dressing on plain copy paper printed with black ink by a laser printer, removed the dressings, examined the adhesive-coated surface of the wound dressings using a high-power videoscope, and examined the stripped areas. Wound dressings coated with a silicone adhesive showed significantly less detachment of the stratum corneum and regenerating epithelium, followed by those coated with polyurethane, hydrocolloid, and acrylic adhesives. The assessment method utilised in this study revealed distinct differences between wound dressing types, but less variation in the evaluation outcome of each type. This assessment method may be useful for the evaluation of adhesive wound dressings, particularly during product development. However, further studies will be needed to examine the effectiveness of this assessment method in the clinical setting because the adherent properties of polyurethane and hydrocolloid adhesives may be altered by the absorption of water from the skin.

  15. Role of natural polysaccharides in radiation formation of PVA hydrogel wound dressing

    NASA Astrophysics Data System (ADS)

    Varshney, Lalit

    2007-02-01

    Radiation processed PVA-polysaccharides hydrogels have been observed to be suitable for producing transparent, flexible, mechanically strong, biocompatible, effective and economical hydrogel dressings. The dressings were formed in single stage irradiation process achieving gel formation and sterilization at 25-30 kGy gamma radiation dose. No synthetic plasticizers and additives were used. Different formulations containing poly-vinylalcohol (PVA) and polysaccharides selected from combinations of agar and carrageenan were used to make the dressings. The selected polysaccharides themselves form thermo-reversible gels and degrade on irradiation. Using concentration of polysaccharides as low as 0.5-2% resulted in increase of tensile strength from 45 g/cm 2 to 411 g/cm 2, elongation from 30% to 410% and water uptake from 25% to 157% with respect to PVA gel without polysaccharides. Besides improving mechanical strength, agar contributes more to elongation and carrageenan to mechanical strength of the gel dressing. PVA formulations containing the polysaccharides show significantly different pre-gel viscosities behaviour. Increasing the concentration of agar in the formulation to about 2% converts the sheet gel to paste gel useful for filling wound cavities. The results indicate that pre irradiation network structure of the formulation plays an important role in determining mechanical properties of the irradiated gel dressing. Formulations containing 7-9% PVA, 0.5-1.5% carrageenan and 0.5-1% agar gave highly effective usable hydrogel dressings. Scanning electron micrographs show highly porous structure of the gel. Clinical trials of wound dressing on human patients established safety and efficacy of the dressing. The dressing has been observed to be useful in treating burns, non-healing ulcers of diabetes, leprosy and other external wounds. The dressings are now being marketed in India under different brand names.

  16. [Application of modern wound dressings in the treatment of chronic wounds].

    PubMed

    Triller, Ciril; Huljev, Dubravko; Smrke, Dragica Maja

    2012-10-01

    Chronic and acute infected wounds can pose a major clinical problem because of associated complications and slow healing. In addition to classic preparations for wound treatment, an array of modern dressings for chronic wound care are currently available on the market. These dressings are intended for the wounds due to intralesional physiological, pathophysiological and pathological causes and which failed to heal as expected upon the use of standard procedures. Classic materials such as gauze and bandage are now considered obsolete and of just historical relevance because modern materials employed in wound treatment, such as moisture, warmth and appropriate pH are known to ensure optimal conditions for wound healing. Modern wound dressings absorb wound discharge, reduce bacterial contamination, while protecting wound surrounding from secondary infection and preventing transfer of infection from the surrounding area onto the wound surface. The use of modern wound dressings is only justified when the cause of wound development has been established or chronic wound due to the underlying disease has been diagnosed. Wound dressing is chosen according to wound characteristics and by experience. We believe that the main advantages of modern wound dressings versus classic materials include more efficient wound cleaning, simpler placement of the dressing, reduced pain to touch, decreased sticking to the wound surface, and increased capacity of absorbing wound exudate. Modern wound dressings accelerate the formation of granulation tissue, reduce the length of possible hospital stay and facilitate personnel work. Thus, the overall cost of treatment is reduced, although the price of modern wound dressings is higher than that of classic materials. All types of modern wound dressings, their characteristics and indications for use are described.

  17. Experimental Comparison of Efficiency of First Aid Dressings in Burning White Phosphorus on Bacon Model

    PubMed Central

    Witkowski, Wojciech; Surowiecka-Pastewka, Agnieszka; Biesaga, Magdalena; Gierczak, Tomasz

    2015-01-01

    Background The aim of this study was to determine effectiveness of first aid dressings in extinguishing burning white phosphorous (WP), eliminating WP pieces from the surface, inhibiting re-ignition on the model (fresh bacon covered with military uniform), and preventing from late re-ignition caused by persistent WP pieces. Material/Methods Burning WP was extinguished with several dressings: tactical Military Dressing (WJ10), wet gauze, 2 hydrocolloids, and 3 prototypes of hydrocolloids developed by the authors. Results All examined dressings were effective in extinguishing WP provided that the entire area of the burning substance was completely covered. Moist gauze was especially effective in extinguishing WP, and also removed and absorbed the majority of the WP mass, preventing deeper penetration of WP particles. The immediate re-ignition was observed when all the remaining examined dressings were removed from the bacon. A stream of water was dangerous, as it splashed and transferred pieces of WP around. Conclusions Moist gauze placed on burning WP for approximately 3 min was most effective in extinguishing WP and removing most of the WP pieces. We recommend moist gauze, used once or twice, as the best primary means for WP elimination and preventing tissue penetration. As a dressing used for medical evacuation (MEDEVAC), or as a second step after complete removal of visible WP, innovative hydrocolloid or hydrogel dressings should be used. PMID:26264209

  18. Assessing clinical efficacy of a hydrocolloid/alginate dressing on full-thickness pressure ulcers.

    PubMed

    Barr, J E; Day, A L; Weaver, V A; Taler, G M

    1995-04-01

    An absorbent hydrocolloid/alginate spiral dressing and a hydrocolloid secondary dressing were used in the management of 30 patients with 30 exuding State III and IV pressure ulcers. After a mean treatment time of 12.9 days (SD 6.5), all wounds had a significant increase in the amount of granulation tissue/epithelium and a decrease in the amount of devitalized tissue (p < 0.05). Wounds that underwent wide surgical debridement prior to the study were covered with 15 percent fibrin slough at study entry versus 39 percent for non-debrided wounds (p < 0.05). The dressing combination facilitated wound contraction and removal of fibrin slough in ulcers that were surgically debrided prior to the study. Ulcers which had not been surgically debrided expanded as autolytic debridement reduced the amount of fibrin slough/necrotic tissue present at the wound bed (Mean: 17.6 percent, p < 0.05). The absorbent spiral dressing helped manage exudate, was easy to use and comfortable for the patients. The average time between dressing changes in these exuding wounds was 1.56 days (SD = 0.95). Use of air-fluidized bed or mattress was found to significantly reduce wear time of the dressing (p < 0.01). Further studies are needed to confirm short-term, and evaluate long-term effects of this dressing combination on healing and debridement.

  19. Atmospheric pressure plasma CVD as a tool to functionalise wound dressings.

    PubMed

    Spange, Sebastian; Pfuch, Andreas; Wiegand, Cornelia; Beier, Oliver; Hipler, Uta C; Grünler, Bernd

    2015-02-01

    The main goal of this investigation was the preparation of an antibacterial layer system for additional modification of wound dressings with atmospheric plasma. Furthermore, the modified wound dressings were checked on there bactericidal and cytotoxic activity. The layer system was applied by using a novel atmospheric pressure plasma chemical vapour deposition technique on a variety of textile substrates which are suitable as wound dressing materials. The layer system composed of silicon dioxide with in situ generated embedded silver nanoparticles. The bactericidal activity of the produced wound dressings was investigated against different bacteria like Staphylococcus aureus and Klebsiella pneumoniae while the cytotoxic potential of the coated wound dressings was verified using human keratinocytes. Even at low concentrations of silver precursor a strong antibacterial effect was observed in direct contact with S. aureus and K. pneumoniae. Furthermore, extractions produced from the coated textiles showed a good antibacterial effect. By means of optimised coating parameters a therapeutic window for those wound dressings could be identified. Consequently, the atmospheric pressure plasma chemical vapour deposition technique promise an effective and low cost modification of wound dressing materials.

  20. Silver-based wound dressings reduce bacterial burden and promote wound healing.

    PubMed

    Lin, Yu-Hsin; Hsu, Wei-Shan; Chung, Wan-Yu; Ko, Tse-Hao; Lin, Jui-Hsiang

    2016-08-01

    Various types of wound dressings have been designed for different purposes and functions. Controlling bacterial burden in a wound during the early phase is important for successful wound repair. Once bacterial burden is under control, the active promotion of wound healing is another important factor for efficient wound healing. This study investigated the potential of three silver-containing dressings, namely KoCarbonAg(®) , Aquacel(®) Ag and Acticoat 7, in reducing bacterial survival and promoting wound healing. The ability of these dressings to block the entry of bacteria from external environment and retain intrinsic bacteria was studied in vitro. In addition, the study used a rat model to compare the healing efficiencies of the three dressings and investigate the quantity of collagen synthesis in vivo. In vitro results indicated that the silver-containing dressings prevented bacterial growth in wounds by blocking the entry of external bacteria and by retaining the bacteria in the dressing. In vivo study indicated that reduction in bacterial burden accelerated wound healing. Wounds treated by the silver-containing dressings showed better healing than those treated with gauze. Moreover, KoCarbonAg(®) further accelerated wound healing by promoting collagen synthesis and arrangement.

  1. Polarisation response of delay dependent absorption modulation in strong field dressed helium atoms probed near threshold

    NASA Astrophysics Data System (ADS)

    Simpson, E. R.; Sanchez-Gonzalez, A.; Austin, D. R.; Diveki, Z.; Hutchinson, S. E. E.; Siegel, T.; Ruberti, M.; Averbukh, V.; Miseikis, L.; Strüber, C. S.; Chipperfield, L.; Marangos, J. P.

    2016-08-01

    We present the first measurement of the vectorial response of strongly dressed helium atoms probed by an attosecond pulse train (APT) polarised either parallel or perpendicular to the dressing field polarisation. The transient absorption is probed as a function of delay between the APT and the linearly polarised 800 nm field of peak intensity 1.3× {10}14 {{W}} {{cm}}-2. The APT spans the photon energy range 16-42 eV, covering the first ionisation energy of helium (24.59 eV). With parallel polarised dressing and probing fields, we observe modulations with periods of one half and one quarter of the dressing field period. When the polarisation of the dressing field is altered from parallel to perpendicular with respect to the APT polarisation we observe a large suppression in the modulation depth of the above ionisation threshold absorption. In addition to this we present the intensity dependence of the harmonic modulation depth as a function of delay between the dressing and probe fields, with dressing field peak intensities ranging from 2 × 1012 to 2 × 1014 {{W}} {{cm}}-2. We compare our experimental results with a full-dimensional solution of the single-atom time-dependent (TD) Schrödinger equation obtained using the recently developed abinitio TD B-spline ADC method and find good qualitative agreement for the above threshold harmonics.

  2. DRESS Syndrome Caused by Cross-reactivity Between Vancomycin and Subsequent Teicoplanin Administration: A Case Report

    PubMed Central

    Miyazu, Daisuke; Kodama, Nobuhiro; Yamashita, Daiki; Tanaka, Hirokazu; Inoue, Sachiko; Imakyure, Osamu; Hirakawa, Masaaki; Shuto, Hideki; Kataoka, Yasufumi

    2016-01-01

    Patient: Male, 79 Final Diagnosis: DRESS Symptoms: Eosinophilia • fever • interstitial pneumonitis • skin rash Medication: Teicoplanin • vancomycin Clinical Procedure: — Specialty: Infectious Diseases Objective: Adverse events of drug therapy Background: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening syndrome comprising severe skin eruption, fever, eosinophilia, lymphadenopathy, and involvement of internal organs. Here, we describe a case of DRESS syndrome caused by cross-reactivity between vancomycin and subsequent teicoplanin administration. Case Report: A 79-year-old male was admitted to our hospital for the treatment of injuries incurred in a traffic accident. Eosinophilia and lung dysfunction appeared after vancomycin administration. These symptoms were improved temporarily by withdrawal of vancomycin and administration of corticosteroid, but exacerbated by subsequent teicoplanin administration. These symptoms disappeared after discontinuation of teicoplanin. Based on comprehensive assessment of the overall clinical course, we judged that DRESS syndrome was induced by cross-reactivity between vancomycin and subsequent teicoplanin administration. Using the European Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) scoring system, we categorized DRESS syndrome related to vancomycin and teicoplanin as “probable.” We describe, for the first time, DRESS syndrome (defined using the RegiSCAR scoring system) caused by cross-reactivity between vancomycin and subsequent teicoplanin administration. Conclusions: Clinicians should be aware that DRESS syndrome can be induced by cross-reactivity between vancomycin and teicoplanin. PMID:27572807

  3. A Wireless Electroceutical Dressing Lowers Cost of Negative Pressure Wound Therapy

    PubMed Central

    Ghatak, Piya Das; Schlanger, Richard; Ganesh, Kasturi; Lambert, Lynn; Gordillo, Gayle M.; Martinsek, Patsy; Roy, Sashwati

    2015-01-01

    Objective: To test whether the use of a wireless electroceutical dressing (WED) (Procellera®) in conjunction with a 5-day negative pressure wound therapy (NPWT) may reduce the number of dressing changes required per week with this therapy. Approach: At the Ohio State University Comprehensive Wound Center, chronic wound patients (n=30) undergoing NPWT were randomized into two arms following consent as approved by the institutional review board. The control arm received standard of care NPWT, where the dressing change was performed thrice a week. The test arm received the same care except that the WED was added as an interface layer and dressing change was limited to twice a week. Results: A reduced cost of care was achieved using the WED in conjunction with NPWT. Despite fewer dressing changes in wounds dressed with the WED, closure outcomes were comparable with no overt signs of any wound complication, including infection. The cost of NPWT care during the week was significantly lower (from $2918 to $2346) in the WED-treated group compared with patients in the control arm. Innovation: This work introduces a novel technology platform involving a WED, which may be used in conjunction with NPWT. If used as such, NPWT is effective in decreasing the frequency of dressing change and lowering the cost of care. Conclusion: This work points toward the benefit of using the WED combined with NPWT. A larger clinical trial investigating the cost-effectiveness of WED in wound care is warranted. PMID:26005596

  4. Influence of hydrophilic polymers on functional properties and wound healing efficacy of hydrocolloid based wound dressings.

    PubMed

    Jin, Sung Giu; Yousaf, Abid Mehmood; Kim, Kyeong Soo; Kim, Dong Wuk; Kim, Dong Shik; Kim, Jin Ki; Yong, Chul Soon; Youn, Yu Seok; Kim, Jong Oh; Choi, Han-Gon

    2016-03-30

    The purpose of this study was to investigate the influence of different hydrophilic polymers on the swelling, bioadhesion and mechanical strength of hydrocolloid wound dressings (HCDs) in order to provide an appropriate composition for a hydrocolloid wound dressing system. In this study, the HCDs were prepared with styrene-isoprene-styrene copolymer (SIS) and polyisobutylene (PIB) as the base using a hot melting method. Additionally, numerous SIS/PIB-based HCDs were prepared with six hydrophilic polymers, and their wound dressing properties were assessed. Finally, the wound healing efficacy of the selected formulations was compared to a commercial wound dressing. The swelling ratio, bioadhesive force and mechanical strengths of HCDs were increased in the order of sodium alginate>sodium CMC=poloxamer=HPMC>PVA=PVP, sodium alginate>sodium CMC=poloxamer>PVA>HPMC=PVP and sodium alginate≥PVA>PVP=HPMC=sodium CMC>poloxamer, respectively. Among the hydrophilic polymers tested, sodium alginate most enhanced the swelling capacity, bioadhesive force and mechanical strengths. Thus, the hydrophilic polymers played great role in the swelling, bioadhesion and mechanical strength of SIS/PIB-based HCDs. The HCD formulation composed of PIB, SIS, liquid paraffin and sodium alginate at the weight ratio of 20/25/12/43 gave better wound dressing properties and more excellent wound healing efficacy than the commercial wound dressing. Therefore, the novel HCD formulation could be a promising hydrocolloid system for wound dressings. PMID:26851354

  5. Clinical Curative Effect of Mesalt Combined with Mepilex Dressing in Postoperative Infection of Inguinal Hernia

    PubMed Central

    Liu, Zhenjun; Xiong, Zhonghua; Wu, Jiayu; Wang, Fang

    2015-01-01

    Background Inguinal hernia is a common surgical disease. Tension-free hernioplasty is currently commonly used for its treatment, with multiple advantages such as simple surgical method, low recurrence rate, and ability to be performed in primary care hospitals, but the risk of incision infection still exists. Mild infection can be cured by local washing, dressing, and systemic antibiotics. If the infection is severe, the wound may not heal after removing the patch, and secondary suturing is needed. Material/Methods A total of 60 patients with postoperative infection after tension-free repair of inguinal hernia were randomly divided into control (n=30) and treatment (n=30) groups. Patients in the treatment group received Mesalt combined with Mepilex for dressing while the patients in the control group received conventional gauze for dressing. Pain degree, wound healing time, and dressing times were observed. Results The clinical therapeutic effect in the treatment group was significantly better than in the control group. The treatment group exhibited significantly less pain when patients receive dressing, shorter wounds healing time (15±3.5 vs. 30±5.0), and less dressing frequency (10±2.1 vs. 20±2.4). Conclusions Mesalt combined with Mepilex can effectively improve postoperative infection after inguinal hernia treatment, obviously reducing pain, shorting wound healing time, and decreasing dressing frequency. It can be widely used in clinical practice. PMID:25854191

  6. The efficacy of silver dressings and antibiotics on MRSA and MSSA isolated from burn patients.

    PubMed

    Percival, Steven L; Thomas, John G; Slone, Will; Linton, Sara; Corum, Linda; Okel, Tyler

    2011-11-01

    In this study our objectives were (1) to investigate whether meticillin-resistant Staphylococcus aureus (MRSA) showed an increased tolerance to silver wound dressings compared with meticillin-sensitive S. aureus (MSSA); and (2) to evaluate the effects of bacterial phenotypic states of MRSA and MSSA, and pH, on the activity of silver wound dressings and two antibiotics, ampicillin and clindamycin. Twenty MRSA strains and 10 MSSA strains isolated from burns patients in South Africa were evaluated for their susceptibility to a silver alginate and a silver carboxymethyl cellulose wound dressing, employing a corrected zone of inhibition assay, conducted on Mueller Hinton agar and a poloxamer-based biofilm model. When exposed to the two silver dressings, all 30 S. aureus strains showed susceptibility. Possible enhanced antimicrobial efficacy of the silver dressings occurred when pH was lowered to 5.5, compared with a pH of 7.0. When all S. aureus were grown in the biofilm phenotypic state and exposed to both silver dressings and antibiotics, enhanced tolerance was noted. Susceptibility to silver was overall higher for MRSA when compared with MSSA. This study showed that the effect of pH and bacterial phenotypic state must be considered when the antimicrobial activity of silver wound dressings is being investigated. It is evident from the data generated that both pH and the bacterial phenotypic state are factors that induce changes that affect both antimicrobial performance and bacterial susceptibility.

  7. Comparative evaluation of the functional properties of superabsorbent dressings and their effect on exudate management.

    PubMed

    Browning, P; White, R J; Rowell, T

    2016-08-01

    A range of wound dressings currently available in the UK and elsewhere, each claiming to possess different performance characteristics, can make dressing selection difficult. This report concentrates on the superabsorbent polymer dressings (SAPs) - which are designed to absorb medium to high levels of exudate and to maintain an 'ideal moist wound healing environment'. What do these dressings achieve, what are they suitable/not suitable for, and are all super-absorbent dressings equal in terms of performance and quality? When assessing the key performance characteristics of absorbency, moisture vapour transmission rate (MVTR), strikethrough and structural integrity, results show that SAPs are not all the same-in fact each of them varies considerably and may lend themselves to different wound aetiologies and usage conditions. While performance data is often presented from non-standard tests or modifications, it is proposed that to provide clarity over dressing selection, all SAPs were measured using International Standards for the key performance characteristics. This will aid clinical staff in selecting the most appropriate dressing for each wound. PMID:27523657

  8. Polarisation response of delay dependent absorption modulation in strong field dressed helium atoms probed near threshold

    NASA Astrophysics Data System (ADS)

    Simpson, E. R.; Sanchez-Gonzalez, A.; Austin, D. R.; Diveki, Z.; Hutchinson, S. E. E.; Siegel, T.; Ruberti, M.; Averbukh, V.; Miseikis, L.; Strüber, C. S.; Chipperfield, L.; Marangos, J. P.

    2016-08-01

    We present the first measurement of the vectorial response of strongly dressed helium atoms probed by an attosecond pulse train (APT) polarised either parallel or perpendicular to the dressing field polarisation. The transient absorption is probed as a function of delay between the APT and the linearly polarised 800 nm field of peak intensity 1.3× {10}14 {{W}} {{cm}}-2. The APT spans the photon energy range 16–42 eV, covering the first ionisation energy of helium (24.59 eV). With parallel polarised dressing and probing fields, we observe modulations with periods of one half and one quarter of the dressing field period. When the polarisation of the dressing field is altered from parallel to perpendicular with respect to the APT polarisation we observe a large suppression in the modulation depth of the above ionisation threshold absorption. In addition to this we present the intensity dependence of the harmonic modulation depth as a function of delay between the dressing and probe fields, with dressing field peak intensities ranging from 2 × 1012 to 2 × 1014 {{W}} {{cm}}-2. We compare our experimental results with a full-dimensional solution of the single-atom time-dependent (TD) Schrödinger equation obtained using the recently developed abinitio TD B-spline ADC method and find good qualitative agreement for the above threshold harmonics.

  9. Robust quantum logic in neutral atoms via adiabatic Rydberg dressing

    NASA Astrophysics Data System (ADS)

    Keating, Tyler; Cook, Robert L.; Hankin, Aaron M.; Jau, Yuan-Yu; Biedermann, Grant W.; Deutsch, Ivan H.

    2015-01-01

    We study a scheme for implementing a controlled-Z (cz) gate between two neutral-atom qubits based on the Rydberg blockade mechanism in a manner that is robust to errors caused by atomic motion. By employing adiabatic dressing of the ground electronic state, we can protect the gate from decoherence due to random phase errors that typically arise because of atomic thermal motion. In addition, the adiabatic protocol allows for a Doppler-free configuration that involves counterpropagating lasers in a σ+/σ- orthogonal polarization geometry that further reduces motional errors due to Doppler shifts. The residual motional error is dominated by dipole-dipole forces acting on doubly excited Rydberg atoms when the blockade is imperfect. For reasonable parameters, with qubits encoded into the clock states of 133Cs, we predict that our protocol could produce a cz gate in <10 μ s with error probability on the order of 10-3.

  10. Dressed polyions, counterion condensation, and adsorption excess in polyelectrolyte solutions.

    PubMed Central

    Mohanty, U; Ninham, B W; Oppenheim, I

    1996-01-01

    The phenomenon of Manning-Oosawa counterion condensation is given an explicit statistical mechanical and qualitative basis via a dressed polyelectrolyte formalism in connection with the topology of the electrostatic free-energy surface and is derived explicitly in terms of the adsorption excess of ions about the polyion via the nonlinear Poisson-Boltzmann equation. The approach is closely analogous to the theory of ion binding in micelles. Our results not only elucidate a Poisson-Boltzmann analysis, which shows that a fraction of the counterions lie within a finite volume around the polyion even if the volume of the system tends towards infinity, but also provide a direct link between Manning's theta-the number of condensed counterions for each polyion site-and a statistical thermodynamic quantity, namely, the adsorption excess per monomer. PMID:8633067

  11. Dressing phases of AdS3/CFT2

    NASA Astrophysics Data System (ADS)

    Borsato, Riccardo; Ohlsson Sax, Olof; Sfondrini, Alessandro; Stefański, Bogdan, Jr.; Torrielli, Alessandro

    2013-09-01

    We determine the all-loop dressing phases of the AdS3/CFT2 integrable system related to type IIB string theory on AdS3×S3×T4 by solving the recently found crossing relations and studying their singularity structure. The two resulting phases present a novel structure with respect to the ones appearing in AdS5/CFT4 and AdS4/CFT3. In the strongly coupled regime, their leading order reduces to the universal Arutyunov-Frolov-Staudacher phase as expected. We also compute their subleading order and compare it with recent one-loop perturbative results and comment on their weak-coupling expansion.

  12. Fatty acid-based polyurethane films for wound dressing applications.

    PubMed

    Gultekin, Guncem; Atalay-Oral, Cigdem; Erkal, Sibel; Sahin, Fikret; Karastova, Djursun; Tantekin-Ersolmaz, S Birgul; Guner, F Seniha

    2009-01-01

    Fatty acid-based polyurethane films were prepared for use as potential wound dressing material. The polymerization reaction was carried out with or without catalyst. Polymer films were prepared by casting-evaporation technique with or without crosslink-catalyst. The film prepared from uncatalyzed reaction product with crosslink-catalyst gave slightly higher crosslink density. The mechanical tests showed that, the increase in the tensile strength and decrease in the elongation at break is due to the increase in the degree of crosslinking. All films were flexible, and resisted to acid solution. The films prepared without crosslink-catalyst were more hydrophilic, absorbed more water. The highest permeability values were generally obtained for the films prepared without crosslink catalyst. Both the direct contact method and the MMT test were applied for determination of cytotoxicity of polymer films and the polyurethane film prepared from uncatalyzed reaction product without crosslink-catalyst showed better biocompatibility property, closest to the commercial product, Opsite.

  13. Addressed qubit manipulation in radio-frequency dressed lattices

    NASA Astrophysics Data System (ADS)

    Sinuco-León, G. A.; Garraway, B. M.

    2016-03-01

    Precise control over qubits encoded as internal states of ultracold atoms in arrays of potential wells is a key element for atomtronics applications in quantum information, quantum simulation and atomic microscopy. Here we theoretically study atoms trapped in an array of radio-frequency dressed potential wells and propose a scheme for engineering fast and high-fidelity single-qubit gates with low error due to cross-talk. In this proposal, atom trapping and qubit manipulation relies exclusively on long-wave radiation making it suitable for atom-chip technology. We demonstrate that selective qubit addressing with resonant microwaves can be programmed by controlling static and radio-frequency currents in microfabricated conductors. These results should enable studies of neutral-atom quantum computing architectures, powered by low-frequency electromagnetic fields with the benefit of simple schemes for controlling individual qubits in large ensembles.

  14. Potential of quaternization-functionalized chitosan fiber for wound dressing.

    PubMed

    Zhou, Yingshan; Yang, Hongjun; Liu, Xin; Mao, Jun; Gu, Shaojin; Xu, Weilin

    2013-01-01

    Quaternization-functionalized chitosan fibers were successfully prepared by using 2,3-epoxypropyl trimethyl ammonium chloride as a quaternized reagent reacted with chitosan fiber. FTIR and (1)H NMR were used to characterize the structure of quaternized chitosan fibers (QCFs). The swelling behavior and mechanical property of QCFs were studied. The results showed that, QCFs had higher liquid absorption capacity than chitosan fiber, while the tensile strength and elongation at break of QCFs were lower than those of chitosan fiber. The antibacterial activity of the QCF had been evaluated by Gram-positive bacteria Staphylococcus aureus (S. aureus). The results indicated that, the antibacterial activity of QCF against S. aureus was stronger than that of chitosan fiber. Indirect cytotoxicity assessment of the fibers indicated that QCF was nontoxic to the L929 cell with relatively low extraction concentration. This novel fiber would be used as potential wound dressing for skin regeneration.

  15. Thawing of Frozen Dressed Tuna by Microwave Heating

    NASA Astrophysics Data System (ADS)

    Tanaka, Takeo; Nagasaki, Tasuku; Takahashi, Kenji

    Large sized frozen yellowfin tuna and southern bluefin tuna in dressed form (decapitated and gutted) were thawed by microwave (915 MHz) irradiation. Temperature rise of the tuna during thawing was measured. Quality of the tuna meat before and after thawing was compared with each other using objective quality index such as degree of discoloration (met-myoglobin ratio), freshness (K1 value) and taste cornponent (K2 value). Results are as follows : (1) Both frozen tunas were thawed fairly well within as short time as 30 min without any partial over heating. (2) No changes in met-myoglobin ratio, K1 and K2 values were observed in the cases of yellow fin tuna. Slight discoloration, however, occurred in southern bluefin tuna meat during microwave thawing. This problem has been left unsolved.

  16. Low-momentum ghost dressing function and the gluon mass

    SciTech Connect

    Boucaud, Ph.; Leroy, J. P.; Le Yaouanc, A.; Micheli, J.; Pene, O.; Gomez, M. E.; Rodriguez-Quintero, J.

    2010-09-01

    We study the low-momentum ghost propagator Dyson-Schwinger equation in the Landau gauge, assuming for the truncation a constant ghost-gluon vertex, as it is extensively done, and a simple model for a massive gluon propagator. Then, regular Dyson-Schwinger equation solutions (the zero-momentum ghost dressing function not diverging) appear to emerge, and we show the ghost propagator to be described by an asymptotic expression reliable up to the order O(q{sup 2}). That expression, depending on the gluon mass and the zero-momentum Taylor-scheme effective charge, is proven to fit pretty well some low-momentum ghost propagator data [I. L. Bogolubsky, E. M. Ilgenfritz, M. Muller-Preussker, and A. Sternbeck, Phys. Lett. B 676, 69 (2009); Proc. Sci., LAT2007 (2007) 290] from big-volume lattice simulations where the so-called ''simulated annealing algorithm'' is applied to fix the Landau gauge.

  17. Fatty acid-based polyurethane films for wound dressing applications.

    PubMed

    Gultekin, Guncem; Atalay-Oral, Cigdem; Erkal, Sibel; Sahin, Fikret; Karastova, Djursun; Tantekin-Ersolmaz, S Birgul; Guner, F Seniha

    2009-01-01

    Fatty acid-based polyurethane films were prepared for use as potential wound dressing material. The polymerization reaction was carried out with or without catalyst. Polymer films were prepared by casting-evaporation technique with or without crosslink-catalyst. The film prepared from uncatalyzed reaction product with crosslink-catalyst gave slightly higher crosslink density. The mechanical tests showed that, the increase in the tensile strength and decrease in the elongation at break is due to the increase in the degree of crosslinking. All films were flexible, and resisted to acid solution. The films prepared without crosslink-catalyst were more hydrophilic, absorbed more water. The highest permeability values were generally obtained for the films prepared without crosslink catalyst. Both the direct contact method and the MMT test were applied for determination of cytotoxicity of polymer films and the polyurethane film prepared from uncatalyzed reaction product without crosslink-catalyst showed better biocompatibility property, closest to the commercial product, Opsite. PMID:18839285

  18. Sauces and dressings: a review of properties and applications.

    PubMed

    Sikora, Marek; Badrie, Neela; Deisingh, Anil K; Kowalski, Stanislaw

    2008-01-01

    This comprehensive review of sauces and salad dressings covers the literature over the last decade with respect to physical and chemical properties and the applications of these products. As such, texturizing and structural systems (especially hydrocolloids) are described in detail and the application of polysaccharide thickeners as texture providers is described. Microbiological aspects of sauces are covered with relevant sections discussing the factors affecting microbiological activity and microbial spoilage and/or enhancement of a range of sauces. In addition, the use of carbohydrates and proteins as emulsifiers in many sauces is described. Quality aspects are given prominence in this review with sections being devoted to rheological and textural properties, chromatographic approaches and sensory aspects. Healthy sauces such as those having low sodium, reduced fat and cholesterol or containing inulin or microcrystalline cellulose are reviewed. Finally, for various sections the trends of the main findings as well as suggestions for future research are presented.

  19. Hyperbranched polyglycerol electrospun nanofibers for wound dressing applications.

    PubMed

    Vargas, E A Torres; do Vale Baracho, N C; de Brito, J; de Queiroz, A A A

    2010-03-01

    This study reports on the performance of electrospun hyperbranched polyglycerol nanofibers capable of providing an active agent delivery for wound dressing applications. The aim of this work was to prepare electrospun HPGL nanofibers containing Calendula officinalis as a wound-healing and anti-inflammatory agent. The morphology of the electrospun HPGL-C. officinalis nanofibers was analyzed using a scanning electron microscope. The results showed that the diameters of the fibers were in nanoscales. The release of C. officinalis from the electrospun HPGL fibers was determined by HPLC at a physiological temperature (37 degrees C). Rapid release of the C. officinalis from the electrospun HPGL-C. officinalis nanofibers was exhibited as result of the high swelling ability as well as the high porosity of the electrospun HPGL-C. officinalis membranes. The degree of swelling, and the mechanical and biocompatible properties of the electrospun HPGL fibers were determined. The results showed that, in physiological conditions, the water absorption into the HPGL electrospun fibers slowed down, governed by the rate at which the electrospun HPGL-C. officinalis membranes interacted with the physiological fluid. The rate of release of C. officinalis seemed to depend on the C. officinalis content in the HPGL nanofibers. From the elastic modulus, it could be seen that elastic electrospun HPGL fibers were obtained with increments of C. officinalis content in the HPGL-C. officinalis membranes. The results of in vivo experiments in rats suggested that HPGL-C. officinalis might be an interesting bioactive wound dressing material for clinical applications.

  20. Development of a wound dressing composed of hyaluronic acid and collagen sponge with epidermal growth factor.

    PubMed

    Kondo, Shinya; Kuroyanagi, Yoshimitsu

    2012-01-01

    This study was designed to investigate the effect of a wound dressing composed of hyaluronic acid (HA) and collagen (Col) sponge containing epidermal growth factor (EGF) on various parameters of wound healing in vitro and in vivo. High-molecular-weight (HMW) HA solution, hydrolyzed low-molecular-weight (LMW) HA solution and heat-denatured Col solution were mixed, followed by freeze-drying to obtain a spongy sheet. Cross-linkage between Col molecules was induced by UV irradiation to the spongy sheet (Type-I dressing). In a similar manner, a spongy sheet containing EGF was prepared (Type-II dressing). The efficacy of these products was firstly evaluated in vitro. Fibroblast proliferation was assessed in culture medium in the presence or absence of a piece of each wound dressing. EGF stimulated cell proliferation after UV irradiation and dry sterilization at 110°C for 1 h. In the second experiment, fibroblasts-embedded Col gels were elevated to the air-liquid interface to create a wound surface model, on which wound dressings were placed and cultured for 1 week. Cell proliferation and the production of vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) were investigated. With Type-II dressings, the amounts of VEGF and HGF released from fibroblasts in the Col gel were significantly increased compared with Type-I dressing. Next, the efficacy of these products was evaluated in vivo using Sprague-Dawley (SD) rats. Wound conditions after 1 and 2 weeks of treatment with the wound dressings were evaluated based on the gross and histological appearances. Type-II dressings promoted a decrease in wound size, re-epithelialization and granulation tissue formation associated with angiogenesis. These findings indicate that the combination of HA, Col and EGF promotes wound healing by stimulating fibroblast function.

  1. Dynamic sensitivity of photon-dressed atomic ensemble with quantum criticality

    SciTech Connect

    Huang Jinfeng; Kuang Leman; Li Yong; Liao Jieqiao; Sun, C. P.

    2009-12-15

    We study the dynamic sensitivity of an atomic ensemble dressed by a single-mode cavity field (called a photon-dressed atomic ensemble), which is described by the Dicke model near the quantum critical point. It is shown that when an extra atom in a pure initial state passes through the cavity, the photon-dressed atomic ensemble will experience a quantum phase transition showing an explicit sudden change in its dynamics characterized by the Loschmidt echo of this quantum critical system. With such dynamic sensitivity, the Dicke model can resemble the cloud chamber for detecting a flying particle by the enhanced trajectory due to the classical phase transition.

  2. Burn dressings: a critical indicator for patient care classification in burn units.

    PubMed

    Driscoll, D M

    1991-12-01

    Nursing services consume approximately 60% of a hospital personnel budget, requiring justification for staffing levels and manpower expenses. The lack of an adequate level of nursing care affects the operation of the entire health care team. The purpose of this descriptive study is to establish the mean tasking time to apply burn dressings. The number of nursing staff required to complete a burn dressing application is dependent on the location of injury and the ability of the patient to cooperate. Establishing the essential mean tasking time for routine post-operative dressing assists in the production of accurate reporting of nursing manpower requirements. PMID:1780065

  3. Recombinant human basic-fibroblastic growth factor: different medical dressings for clinical application in wound healing.

    PubMed

    Finetti, G; Farina, M

    1992-06-01

    Recombinant human basic-Fibroblastic Growth Factor (rhb-FGF) is a basic single-chain protein showing high activity as mitogenetic and angiogenetic agent. The application of rhb-FGF in wound healing as stimulator of the tissue repair process is strictly connected with the covering of the wound by means of a proper dressing. A wide number of synthetic occlusive or non-occlusive wound dressings has been developed. Owing to the delicate proteic structure of rhb-FGF, and generally of all the Growth Factors, compatibility with the dressings has to be every time tested, to avoid its inactivation and consequent loss of tissue repair properties.

  4. The properties of the “ideal” donor site dressing: results of a worldwide online survey

    PubMed Central

    Lars, P. Kamolz L.P.; Giretzlehner, M.; Trop, M.; Parvizi, D.; Spendel, S.; Schintler, M.; Justich, I.; Wiedner, M.; Laback, C.; Lumenta, D.B..

    2013-01-01

    Summary Split skin grafting is a widely used technique for reconstructing skin defects. Although a vast number of different coverage options for donor sites have become available in daily clinical practice, no optimum dressing material has been found to date. For this reason, we conducted a globally-distributed online survey to poll for the properties of such an “ideal” donor site dressing, possibly leading to an improved clinically-driven direction of future wound dressing developments. A total of 69 respondents from 34 countries took part in the questionnaire, resulting in a response rate of 13.8% (69/500) over a 1-month period. The majority of respondents rated the characteristics of an “ideal” donor site dressing to be either “essential” or “desirable” as follows: lack of adhesion to the wound bed (“essential”: 31/69, 44.9%; “desirable”: 30/69, 43.5%); pain-free dressing changes (“essential”: 38/69, 55.1%; “desirable”: 30/69, 43.5%); absorbency (“essential”: 27/69, 39.1%; “desirable”: 33/69, 47.8%); ease of removal (“essential”: 37/69, 53.6%; “desirable”: 27/69, 39.13%). With regard to the desired frequency of dressing changes, respondents preferred “no dressing change until the donor site has healed” (51/69, 73.9%) in the majority of cases, followed by “twice weekly” (10/69, 14.5%), “alternate days” (5/69, 7.2%) and “daily” (3/69, 4.3%). With regard to the design of the dressing material, the majority of participants preferred a one-piece (composite) dressing product (44/69, 63.8%). The majority of respondents also denied the current availability of an “ideal” donor site dressing (49/69, 71%). The strength of this study was the remarkable geographic distribution of responses; all parts of the world were included and participated. We believe that this globally conducted online survey has polled for the properties of the “ideal” donor site dressing and possibly will lead to an improved

  5. The properties of the "ideal" donor site dressing: results of a worldwide online survey.

    PubMed

    Lars, P Kamolz L P; Giretzlehner, M; Trop, M; Parvizi, D; Spendel, S; Schintler, M; Justich, I; Wiedner, M; Laback, C; Lumenta, D B

    2013-09-30

    Split skin grafting is a widely used technique for reconstructing skin defects. Although a vast number of different coverage options for donor sites have become available in daily clinical practice, no optimum dressing material has been found to date. For this reason, we conducted a globally-distributed online survey to poll for the properties of such an "ideal" donor site dressing, possibly leading to an improved clinically-driven direction of future wound dressing developments. A total of 69 respondents from 34 countries took part in the questionnaire, resulting in a response rate of 13.8% (69/500) over a 1-month period. The majority of respondents rated the characteristics of an "ideal" donor site dressing to be either "essential" or "desirable" as follows: lack of adhesion to the wound bed ("essential": 31/69, 44.9%; "desirable": 30/69, 43.5%); pain-free dressing changes ("essential": 38/69, 55.1%; "desirable": 30/69, 43.5%); absorbency ("essential": 27/69, 39.1%; "desirable": 33/69, 47.8%); ease of removal ("essential": 37/69, 53.6%; "desirable": 27/69, 39.13%). With regard to the desired frequency of dressing changes, respondents preferred "no dressing change until the donor site has healed" (51/69, 73.9%) in the majority of cases, followed by "twice weekly" (10/69, 14.5%), "alternate days" (5/69, 7.2%) and "daily" (3/69, 4.3%). With regard to the design of the dressing material, the majority of participants preferred a one-piece (composite) dressing product (44/69, 63.8%). The majority of respondents also denied the current availability of an "ideal" donor site dressing (49/69, 71%). The strength of this study was the remarkable geographic distribution of responses; all parts of the world were included and participated. We believe that this globally conducted online survey has polled for the properties of the "ideal" donor site dressing and possibly will lead to an improved clinically-driven direction of future wound dressing development.

  6. [Human herpes virus 6 infection in an inmunocompetent patient with carbamazepine-induced DRESS syndrome].

    PubMed

    Álvarez, Sergio; Delama, Ignacio; Navajas-Galimany, Lucas; Eymin, Gonzalo; Ceballos, M Elena; Andino-Navarrete, Romina

    2016-06-01

    DRESS syndrome (drug reaction with eosinophilia and systemic symptoms) is an adverse life-threatening drug reaction characterized by a polymorphous rash associated with fever, lymphadenopathy and multiorgan involvement with eosinophilia. We present the case of an immunocompetent man with DRESS syndrome secondary to carbamazepine, that developed concomitantly meningoencephalitis caused by human herpes virus 6 (HHV-6), and a review of literature. The pathogenic role of HHV-6 in DRESS syndrome remains controversial. Given the diagnostic and possibly prognostic significance of HHV-6, the screening seems to be a good measure to use in the clinical management of these patients. PMID:27598287

  7. Blue-Black or White-Gold? Early Stage Processing and the Color of 'The Dress'

    PubMed Central

    Rabin, Jeff

    2016-01-01

    Purpose In Feb 2015 an image of a dress posted on Tumblr triggered an internet phenomenon: Is the Dress blue and black (BB) or white and gold (WG)? Many claim BB and others insist WG while the true colors are BB. The prevailing theory is that assumptions about the illuminant govern perception of the Dress with WG due to bluish lighting and BB due to yellowish. Our purpose was to determine if early stage optical, retinal and/or neural factors also impact perception of the Dress. Methods Thirty-nine subjects were categorized as BB or WG based on their initial perception of the Dress and their perception reported when viewing the Dress on iPhone 5, iPad, and 22” LCD displays. Macular pigment optical density (MPOD) measured with the QuantifEye™ MPS II and visual brainwaves (VEPs) in response to brief presentations of a transparency of the Dress illuminated by a flashing light were measured on each subject and compared between BB and WG groups. Additionally, CIE chromaticity (color) and luminance (brightness) were measured from multiple areas of the Dress image to determine cone stimulation and contrast. Results Mean MPOD was higher in the WG group (0.49) vs. the BB (0.41, p = 0.04) and median values were higher as well (WG = 0.46, BB = 0.36, p = 0.03). There was no difference in VEP amplitude between groups (p > 0.85) but mean VEP latency was longer in WG (130 msec.) vs. the BB group (107 msec., p = 0.0005). Colorimetry of the Dress showed significantly greater stimulation of blue cones (contrast = 73%) vs. red and green sensitive cones (contrast = 13%). Conclusions Our findings indicate that observers with denser MPOD may be predisposed to perceive the Dress as WG due to great absorption of blue light by the macular pigment. Moreover, the novel, substantial stimulation of blue cones by the Dress may contribute to ambiguity and dichotomous perception since the blue cones are so sparse in the retina. Finally, the delayed WG VEPs indicate distinct neural processing

  8. The properties of the "ideal" donor site dressing: results of a worldwide online survey.

    PubMed

    Lars, P Kamolz L P; Giretzlehner, M; Trop, M; Parvizi, D; Spendel, S; Schintler, M; Justich, I; Wiedner, M; Laback, C; Lumenta, D B

    2013-09-30

    Split skin grafting is a widely used technique for reconstructing skin defects. Although a vast number of different coverage options for donor sites have become available in daily clinical practice, no optimum dressing material has been found to date. For this reason, we conducted a globally-distributed online survey to poll for the properties of such an "ideal" donor site dressing, possibly leading to an improved clinically-driven direction of future wound dressing developments. A total of 69 respondents from 34 countries took part in the questionnaire, resulting in a response rate of 13.8% (69/500) over a 1-month period. The majority of respondents rated the characteristics of an "ideal" donor site dressing to be either "essential" or "desirable" as follows: lack of adhesion to the wound bed ("essential": 31/69, 44.9%; "desirable": 30/69, 43.5%); pain-free dressing changes ("essential": 38/69, 55.1%; "desirable": 30/69, 43.5%); absorbency ("essential": 27/69, 39.1%; "desirable": 33/69, 47.8%); ease of removal ("essential": 37/69, 53.6%; "desirable": 27/69, 39.13%). With regard to the desired frequency of dressing changes, respondents preferred "no dressing change until the donor site has healed" (51/69, 73.9%) in the majority of cases, followed by "twice weekly" (10/69, 14.5%), "alternate days" (5/69, 7.2%) and "daily" (3/69, 4.3%). With regard to the design of the dressing material, the majority of participants preferred a one-piece (composite) dressing product (44/69, 63.8%). The majority of respondents also denied the current availability of an "ideal" donor site dressing (49/69, 71%). The strength of this study was the remarkable geographic distribution of responses; all parts of the world were included and participated. We believe that this globally conducted online survey has polled for the properties of the "ideal" donor site dressing and possibly will lead to an improved clinically-driven direction of future wound dressing development. PMID:24563639

  9. Development of novel wound dressing composed of hyaluronic acid and collagen sponge containing epidermal growth factor and vitamin C derivative.

    PubMed

    Niiyama, Hayato; Kuroyanagi, Yoshimitsu

    2014-03-01

    This study was designed to investigate the potential of a wound dressing composed of hyaluronic acid (HA) and collagen (Col) spongy sheet containing epidermal growth factor (EGF) and vitamin C derivative (VC). High-molecular-weight HA aqueous solution, hydrolyzed low-molecular-weight HA aqueous solution and heat-denatured Col aqueous solution were mixed, followed by freeze-drying to obtain a spongy sheet. Cross-linkage between Col molecules was induced by UV irradiation of the spongy sheet (C-wound dressing). In a similar manner, three types of spongy sheet containing EGF (EGF-wound dressing), containing VC (VC-wound dressing) or containing EGF and VC (EGF·VC-wound dressing) were prepared by freeze-drying the mixed solution containing the specified components. Cytokine production by fibroblasts was assessed in a wound surface model using a fibroblast-incorporating Col gel sheet (cultured dermal substitute; CDS). CDS was elevated to the air-medium interface, onto which each wound dressing was placed and cultured for 7 days. Fibroblasts in CDS covered with EGF-wound dressing released 3.6 times more VEGF and 3.0 times more HGF, as compared with the C-wound dressing. Fibroblasts in CDS covered with EGF·VC-wound dressing released 4.2 times more VEGF and 6.0 times more HGF, as compared with the C-wound dressing. The efficacy of these wound dressings was evaluated in animal tests using diabetic mice. Each wound dressing was applied to a full-thickness skin defect on the dorsal area measuring 1.5 × 2.0 cm. After 1 week of application, wound conditions were evaluated histologically. The EGF·VC-wound dressing more effectively promoted granulation tissue formation associated with angiogenesis, as compared with other wound dressings.

  10. Development of a wound dressing composed of hyaluronic acid sponge containing arginine and epidermal growth factor.

    PubMed

    Matsumoto, Yasuhiro; Kuroyanagi, Yoshimitsu

    2010-01-01

    Hyaluronic acid (HA) has the ability to promote wound healing. Epidermal growth factor (EGF) is able to promote the proliferation of various cell types, in addition to epidermal cells. A novel wound dressing was designed using high-molecular-weight hyaluronic acid (HMW-HA) and low-molecular-weight hyaluronic acid (LMW-HA). Spongy sheets composed of cross-linked high-molecular-weight hyaluronic acid (c-HMW-HA) were prepared by freeze-drying an aqueous solution of HMW-HA containing a crosslinking agent. Each spongy sheet was immersed into an aqueous solution of LMW-HA containing arginine (Arg) alone or both Arg and epidermal growth factor (EGF), and were then freeze-dried to prepare two types of product. One was a wound dressing composed of c-HMW-HA sponge containing LMW-HA and Arg (c-HMW-HA/LMW-HA + Arg; Group I). The other was a wound dressing composed of c-HMW-HA sponge containing LMW-HA, Arg and EGF (c-HMW-HA/LMW-HA + Arg + EGF; Group II). The efficacy of these products was evaluated in animal tests using rats. In the first experiment, each wound dressing was applied to a full-thickness skin defect with a diameter of 35 mm in the abdominal region of Sprague-Dawley (SD) rats, leaving an intact skin island measuring 15 mm in diameter in the central area of this skin defect. Commercially available polyurethane film dressing was then applied to each wound dressing as a covering material. In the control group, the wound surface was covered with polyurethane film dressing alone. Both wound dressings (Group I and Group II) potently decreased the size of the full-thickness skin defect and increased the size of the intact skin island, when compared with the control group. The wound dressing in Group II showed particularly potent activity in increasing the distance of epithelization from the intact skin island. This suggests that EGF release from the spongy sheet serves to promote epithelization. The wound dressing in Group II enhanced early-stage inflammation after 1 week

  11. The effectiveness of hydrocolloid dressings versus other dressings in the healing of pressure ulcers in adults and older adults: a systematic review and meta-analysis1

    PubMed Central

    Pott, Franciele Soares; Meier, Marineli Joaquim; Stocco, Janislei Giseli Dorociak; Crozeta, Karla; Ribas, Janyne Dayane

    2014-01-01

    Objective to evaluate the effectiveness of hydrocolloids in the healing of pressure ulcers in adult and older adult patients. Method systematic review with meta-analysis, based on the recommendations of the Cochrane Handbook. The search was undertaken in the databases: Medical Literature Analysis and Retrieval System Online, Latin American and Caribbean Health Sciences Literature (LILACS), Cochrane Database, Cumulative Index to Nursing and Allied Health Literature, Web of Science and the Scientific Electronic Library Online. Results 646 primary studies were identified, 69 were evaluated and nine were selected, referring to the use of the hydrocolloid dressing in healing; of these, four studies allowed meta-analysis. There was no statistically significant difference between the hydrocolloid group and the foams group (p value=0.84; Odds Ratio 1.06, CI 95% 0.61-1.86). A slight superiority of the polyurethane dressings was observed in relation to the hydrocolloid dressings. Conclusion the evidence is not sufficient to affirm whether the efficacy of hydrocolloid dressings is superior to that of other dressings. It is suggested that clinical randomized trials be undertaken so as to ascertain the efficacy of this intervention in the healing of pressure ulcers, in relation to other treatments. PMID:25029065

  12. Hydrocellular foam dressings promote wound healing associated with decrease in inflammation in rat periwound skin and granulation tissue, compared with hydrocolloid dressings.

    PubMed

    Yamane, Takumi; Nakagami, Gojiro; Yoshino, Sawako; Shimura, Mari; Kitamura, Aya; Kobayashi-Hattori, Kazuo; Oishi, Yuichi; Nishijima, Yoshimi; Minematsu, Takeo; Sanada, Hiromi

    2015-01-01

    The effects of modern dressings on inflammation, which represent the earliest phase of wound healing, are poorly understood. We investigated the effects of modern hydrocellular foam dressings (HCFs) on wound healing and on the gene expression levels of the inflammatory markers--interleukin (IL)-1β, IL-6, and IL-10--in rat periwound skin and granulation tissue by quantitative reverse transcription-polymerase chain reaction. HCF absorbed significantly higher volume of water than hydrocolloid dressing (HCD) and increased the contraction of wounds. Polymorphonuclear neutrophils were massively infiltrated to the wound edge and boarded between granulation and dermis in the HCD group. IL-1β, IL-6, and IL-10 mRNA levels were significantly decreased in the periwound skin around the wounds and granulation tissue covered with HCF. These findings suggest that HCF may promote wound healing along with decrease in inflammation by reducing gene expression levels of IL-1β, IL-6, and IL-10.

  13. Surface waviness resulting from single point diamond dressing in cylindrical grinding

    SciTech Connect

    Redmond, J.; Hinnerichs, T.; Apodaca, E.

    1996-05-01

    This paper describes an experimental investigation of workpiece surface waviness that stems from poor single point diamond wheel dressing procedures in cylindrical grinding. If done improperly, single point dressing can produce a thread on the grinding wheel surface that is then imposed on the workpiece during machining. The circumferential waviness exhibited by the threaded workpiece is similar to that resulting from one per rev vibrations of the grinding wheel. In order to differentiate between these two sources of waviness, a geometrical approach to predicting the circumferential and axial waves produced during grinding is presented. The concepts presented are illustrated through a series of plunge grinding tests incorporating dressing procedures of varying quality. Test results verify that dressing induced circumferential waviness is similar to waviness resulting from one per rev type vibrations of the grinding wheel. The two sources can be distinguished, however, through examination of the workpiece waviness in the axial direction.

  14. Dressings as an adjunct to pressure ulcer prevention: consensus panel recommendations.

    PubMed

    Black, Joyce; Clark, Michael; Dealey, Carol; Brindle, Christopher T; Alves, Paulo; Santamaria, Nick; Call, Evan

    2015-08-01

    The formulation of recommendations on the use of wound dressings in pressure ulcer prevention was undertaken by a group of experts in pressure ulcer prevention and treatment from Australia, Portugal, UK and USA. After review of literature, they concluded that there is adequate evidence to recommend the use of five-layer silicone bordered dressings (Mepilex Border Sacrum(®) and 3 layer Mepilex Heel(®) dressings by Mölnlycke Health Care, Gothenburg, Sweden) for pressure ulcer prevention in the sacrum, buttocks and heels in high-risk patients, those in Emergency Department (ED), intensive care unit (ICU) and operating room (OR). Literature on which this recommendation is based includes one prospective randomised control trial, three cohort studies and two case series. Recommendations for dressing use in patients at high risk for pressure injury and shear injury were also provided.

  15. Assessing an adherent silicone foam dressing: a clinical evaluation across five NHS trusts.

    PubMed

    Stephen-Haynes, Jackie; Callaghan, Rosie; Bethell, Elaine; Linthwaite, Adele; Bullough, Lindsey; Armstrong, Jayne

    2015-12-01

    The wound contact layer of UrgoTul Absorb Border (Urgo Medical) foam dressing contains a Technology Lipido Colloid (TLC) Healing Matrix, which includes hydrocolloid and lipophilic substances designed to stimulate fibroblast proliferation and thus promote granulation tissue formation. A multicentre, noncomparative, clinical evaluation of UrgoTul Absorb Border investigated whether use of the dressing promoted granulation tissue formation and the management of wound exudate. Other parameters evaluated included: pain-free dressing changes, protection and improvement of surrounding tissue, ease of application, conformability, ability to remain in place, wear time, effect on peri-wound skin, durability, ease of removal, and patient comfort. There were 43 patients recruited into the evaluation. Results show that 8 wounds (19%) achieved full epithelialisation and 34 (81%) improved. All participating clinicians rated the dressing's overall performance, including its ability to manage exudate, as excellent, very good, or good. PMID:26639071

  16. Dressed adiabatic and diabatic potentials to study conical intersections for F + H2

    NASA Astrophysics Data System (ADS)

    Das, Anita; Sahoo, Tapas; Mukhopadhyay, Debasis; Adhikari, Satrajit; Baer, Michael

    2012-02-01

    We follow a suggestion by Lipoff and Herschbach [Mol. Phys. 108, 1133 (2010), 10.1080/00268971003662912] and compare dressed and bare adiabatic potentials to get insight regarding the low-energy dynamics (e.g., cold reaction) taking place in molecular systems. In this particular case, we are interested to study the effect of conical intersections (ci) on the interacting atoms. For this purpose, we consider vibrational dressed adiabatic and vibrational dressed diabatic potentials in the entrance channel of reactive systems. According to our study, the most one should expect, in case of F + H2, is a mild effect of the (1, 2) ci on its reactive/exchange process-an outcome also supported by experiment. This happens although the corresponding dressed and bare potential barriers (and the corresponding van der Waals potential wells) differ significantly from each other.

  17. Effect of bound-state dressing in laser-assisted radiative recombination

    NASA Astrophysics Data System (ADS)

    Müller, Robert A.; Seipt, Daniel; Fritzsche, Stephan; Surzhykov, Andrey

    2015-11-01

    We present a theoretical study on the recombination of a free electron into the ground state of a hydrogenlike ion in the presence of an external laser field. Emphasis is placed on the effects caused by the laser dressing of the residual ionic bound state. To investigate how this dressing affects the total and angle-differential cross section of laser-assisted radiative recombination (LARR) we apply first-order perturbation theory and the separable Coulomb-Volkov continuum ansatz. Using this approach, detailed calculations are performed for low-Z hydrogenlike ions and laser intensities in the range from IL=1012 to 1013W/cm2 . It is seen that the total cross section as a function of the laser intensity is remarkably affected by the bound-state dressing. Moreover, the laser dressing becomes manifest as asymmetries in the angular distribution and the (energy) spectrum of the emitted recombination photons.

  18. Protecting a Solid-State Spin from Decoherence Using Dressed Spin States

    NASA Astrophysics Data System (ADS)

    Golter, D. Andrew; Baldwin, Thomas K.; Wang, Hailin

    2014-12-01

    We report experimental studies of dressing an electron spin in diamond with resonant and continuous microwave fields to protect the electron spin from magnetic fluctuations induced by the nuclear spin bath. We use optical coherent population trapping (CPT) to probe the energy level structure, optically induced spin transitions, and spin decoherence rates of the dressed spin states. Dressing an electron spin with resonant microwaves at a coupling rate near 1 MHz leads to a 50 times reduction in the linewidth of the spin transition underlying the CPT process, limited by transit-time broadening. Compared with dynamical decoupling, where effects of the bath are averaged out at specific times, the dressed spin state provides a continuous protection from decoherence.

  19. 13. Interior view of break/dressing room in rehabilitation and testing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Interior view of break/dressing room in rehabilitation and testing facilities; showing casework and exterior window; southeast corner of occupied portion; view to west. - Ellsworth Air Force Base, Mess & Administration Building, 2279 Risner Drive, Blackhawk, Meade County, SD

  20. Reducing infection in chronic leg ulcers with an activated carbon cloth dressing.

    PubMed

    Murphy, Nina

    2016-06-23

    Zorflex is a new type of antimicrobial dressing composed of 100% activated carbon cloth. It attracts and binds bacteria to its surface, enabling them to be safely removed at dressing change. It has no reported toxic effects and can be used on either a short-or long-term basis. This article describes 4 case studies in which patients with recalcitrant chronic venous leg ulcers that were prone to recurrent infection were treated with the activated carbon cloth dressing. All of the wounds had failed to respond to antimicrobial dressings containing silver, iodine or polyhexamethylene biguanide (PHMB), and were heavily exuding and painful. In all cases, the signs of infection reduced significantly within 4 weeks, resulting in good patient outcomes. PMID:27345081

  1. Two-body interactions and decay of three-level Rydberg-dressed atoms

    NASA Astrophysics Data System (ADS)

    Helmrich, S.; Arias, A.; Pehoviak, N.; Whitlock, S.

    2016-02-01

    We theoretically analyze the interactions and decay rates for atoms dressed by multiple laser fields to strongly interacting Rydberg states using a quantum master equation approach. In this framework a comparison of two-level and three-level Rydberg-dressing schemes is presented. We identify a resonant enhancement of the three-level dressed interaction strength which originates from cooperative multiphoton couplings as well as small distance dependent decay rates. In this regime the soft-core shape of the potential is independent of the sign of the bare Rydberg-Rydberg interaction, while its sign can be repulsive or attractive depending on the intermediate state detuning. As a consequence, near-resonant Rydberg dressing in three-level atomic systems may enable the realization of laser driven quantum fluids with long-range and anisotropic interactions and with controllable dissipation.

  2. A comparative study of 'Op-site' and 'Nobecutan gauze' dressings for central venous line care.

    PubMed

    Andersen, P T; Herlevsen, P; Schaumburg, H

    1986-03-01

    A comparative study of 'Op-site' and 'Nobecutan-gauze' dressings for central venous lines was performed. Seventy-seven long antebrachial and 68 infraclavicular subclavian catheters were studied. A statistically significant reduction in the incidence of positive cultures from the catheter tip and from the skin puncture site was found with the 'Nobecutan-gauze' dressing. No difference in the incidence of catheter-related septicaemia was found. The theoretical advantage of being able to observe signs of inflammation when 'Op-site' was used did not reduce the incidence of local infection at the skin puncture site. In conclusion we found that a 'Nobecutan-gauze' dressing was a satisfactory alternative to an 'Op-site' dressing.

  3. Pain and anxiety with burn dressing changes: patient self-report.

    PubMed

    Weinberg, K; Birdsall, C; Vail, D; Marano, M A; Petrone, S J; Mansour, E H

    2000-01-01

    Pain and anxiety are integral parts of burn dressing care. Descriptions of pain and anxiety from the patients' perspectives enhance our understanding of their experiences. This descriptive study measured relationships between self-reported pain and anxiety. Twenty-four patients who had an uncomplicated flame or scald wound reported scores immediately before, immediately after, and 1/2 hour after dressing changes. Results indicated that pain and anxiety increased until day 4. Pain correlated with anxiety. Self-report scores showed that pain and anxiety are perceived by patients in a similar manner. Self-report scores are of great value because they indicate the degree of relief achieved with medication. Through the descriptive study, we found that the pain score immediately after dressing changes was greater than 3 on all study days. This finding indicates a need to further examine the way pain is managed with dressing changes. PMID:10752749

  4. Wound dressing composed of hyaluronic acid and collagen containing EGF or bFGF: comparative culture study.

    PubMed

    Yu, Akane; Niiyama, Hayato; Kondo, Shinya; Yamamoto, Akiko; Suzuki, Ryusuke; Kuroyanagi, Yoshimitsu

    2013-01-01

    We developed a novel wound dressing composed of a hyaluronic acid (HA) and collagen (Col) spongy sheet containing epidermal growth factor (EGF) or basic fibrolast growth factor (bFGF) by freeze-drying method (EGF-wound dressing or bFGF-wound dressing, respectively). A wound dressing without any growth factor was prepared as a control in a similar manner as above (C-wound dressing). Intermolecular cross-linkage between Col molecules was induced by UV irradiation. The release behavior of free HA from the wound dressing was investigated using a C-wound dressing. The weight of C-wound dressing after 1 day, 3, 5, and 7 days of incubation on top of a Col gel sheet at the air-water interface (wound surface model) was 55, 36, 30, and 19% of the original weight, respectively. Most free HA and a part of Col was released from the cross-linked Col network in the wound dressing during incubation, as the original Col content in the wound dressing was 33%. Next, fibroblast proliferation was assessed in conventional culture medium preconditioned by immersion of a piece of C-, EGF-, or bFGF-wound dressing, i.e. C-conditioned medium, EGF-conditioned medium, or bFGF-conditioned medium. Cell proliferation in C-conditioned medium increased to approximately the same level as that in conventional medium. Cell proliferation in EGF- and bFGF-conditioned medium was 1.9 times and 2.6 times greater than that in conventional medium after 7 days of cultivation, respectively. Finally, cytokine production of fibroblasts was assessed in a wound surface model using a fibroblast-incorporating Col gel sheet (cultured dermal substitute [CDS]). CDS was elevated to the air-medium interface, on which each wound dressing was placed and cultured for 7 days. Fibroblasts in CDS covered with EGF-wound dressing released 3.6 times more vascular endothelial growth factor (VEGF) and 4.6 times more hepatocyte growth factor (HGF) when compared with the C-wound dressing. Fibroblasts in CDS covered with b

  5. Putting on the style: what patients think of the way their doctor dresses.

    PubMed Central

    McKinstry, B; Wang, J X

    1991-01-01

    The aim of this study was to determine how acceptable patients found different styles of doctors' dress and whether patients felt that a doctor's style of dress influenced their respect for his or her opinion. A total of 475 patients from five general practices in Lothian were surveyed using photographs of different styles in a male and female doctor and questions about their attitudes to doctors' dress in general. Overall, patients seemed to favour a more formal approach to dress, with the male doctor wearing a formal suit and tie and the female doctor in a white coat scoring the most high marks. This was particularly true of older patients and those in social classes 1 and 2. The male doctor wearing a tweed jacket and informal shirt and tie scored fewer low marks and this was therefore the least disliked of the outfits. There was a marked variation between preferences of patients registered with different practices. When asked, 28% of patients said they would be unhappy about consulting one of doctors shown, usually the ones who were informally dressed. However, some patients said they would dislike their doctor wearing a white coat. Although there are more important attributes for a general practitioner than the way he or she dresses, a majority of patients (64%) thought that the way their doctor dressed was very important or quite important. Given that 41% of the patients said they would have more confidence in the ability of one of the doctors based on their appearance it would seem logical for doctors to dress in a way that inspires confidence.(ABSTRACT TRUNCATED AT 250 WORDS) Images A B C D E F G H PMID:1747264

  6. Dressing method for the vector sine-Gordon equation and its soliton interactions

    NASA Astrophysics Data System (ADS)

    Mikhailov, Alexander V.; Papamikos, Georgios; Wang, Jing Ping

    2016-06-01

    In this paper, we develop the dressing method to study the exact solutions for the vector sine-Gordon equation. The explicit formulas for one kink and one breather are derived. The method can be used to construct multi-soliton solutions. Two soliton interactions are also studied. The formulas for position shift of the kink and position and phase shifts of the breather are given. These quantities only depend on the pole positions of the dressing matrices.

  7. A Comparison of the Efficacy and Cost of Different Venous Leg Ulcer Dressings: A Retrospective Cohort Study

    PubMed Central

    Hussain, Syed M. Asim

    2015-01-01

    Objective. To compare the efficacy and cost-effectiveness of simple nonadherent dressings with other more expensive dressing types in the treatment of venous leg ulcers. Study Design. Retrospective cohort study. Location. The leg ulcer clinic at the University Hospital of South Manchester. Subjects and Methods. The healing rates of twelve leg ulcer patients treated with simple nonadherent dressings (e.g., NA Ultra) were compared with an equal number of patients treated with modern dressings to determine differences in healing rates and cost. Main Outcome Measures. Rate of healing as determined by reduction in ulcer area over a specified period of time and total cost of dressing per patient. Results. Simple nonadherent dressings had a mean healing rate of 0.353 cm2/week (standard deviation ± 0.319) compared with a mean of 0.415 cm2/week (standard deviation ± 0.383) for more expensive dressings. This resulted in a one-tailed p value of 0.251 and a two-tailed p value of 0.508. Multiple regression analysis gave a significance F of 0.8134. Conclusion. The results indicate that the difference in healing rate between simple and modern dressings is not statistically significant. Therefore, the cost of dressing type should be an important factor influencing dressing selection. PMID:25954532

  8. Identifying prognostic factors for drug rash with eosinophilia and systemic symptoms (DRESS).

    PubMed

    Wei, Chia-Hung; Chung-Yee Hui, Rosaline; Chang, Chee-Jen; Ho, Hsin-Chun; Yang, Chih-Hsun; Lin, Yu-Jr; Chung, Wen-Hung

    2011-01-01

    Drug rash with eosinophilia and systemic symptoms (DRESS) is a severe cutaneous drug reaction. Although the severity-of-illness score (SCORTEN) has been proposed for toxic epidermal necrolysis (TEN) for 10 years, a prognostic score for DRESS is still lacking. To identify prognostic factors of DRESS patients during hospitalization in one medical health system in Taiwan. We retrospectively reviewed all patients with DRESS diagnosed by dermatologists in Chang Gung Memorial Hospital (CMGH) Health System from 2001 to 2010. To study prognostic factors, we collected data at early disease and maximal disease stages. 91 individuals, including 13 dead patients, were evaluated. Five independent prognostic factors of death were found: heart rate > 90/min, white blood cells >12,000/mm(3) and respiratory rate >20/min (at early disease stage), coagulopathy and gastrointestinal bleeding (at maximal disease stage). In addition, systemic inflammatory response syndrome (SIRS) occurred at a much higher percentage among non-survivors throughout hospitalization. We found tachycardia, leukocytosis, tachypnea, coagulopathy, gastrointestinal bleeding and SIRS were associated with a poor outcome in DRESS patients. DRESS patients with persistent SIRS during hospitalization were also associated with a higher mortality risk. Early recognition and prompt intervention in these factors may improve outcome.

  9. Incorporating gold into nanocrystalline silver dressings reduces grain boundary size and maintains suitable antimicrobial properties.

    PubMed

    Unrau, Kevin R; Cavanagh, Marion H; Cheng, On Kwan; Wang, Shiman; Burrell, Robert E

    2013-12-01

    Nanocrystalline silver dressings are widely known to be potent antimicrobial and anti-inflammatory agents and have long been used to treat topical wounds. Gold is known to be a strong anti-inflammatory agent and has been used in the treatment of rheumatoid arthritis for >70 years. The purpose of this work was to study the effect of incorporating gold into nanocrystalline silver dressings from antimicrobial and anti-inflammatory perspectives. Gold and silver dressing alloys were created by direct current magnetron sputtering and compared with pure silver nanocrystalline dressings using conventional biological (log reduction and corrected zone of inhibition) and physical (X-ray diffraction, X-ray photoelectron spectroscopy, energy-dispersive X-ray spectroscopy, atomic absorption spectroscopy, atomic force microscopy and scanning electron microscopy) characterisation techniques. While the gold/silver dressings were slightly weaker antimicrobials than the pure silver nanocrystalline structures, the addition of gold to the nanostructure reduces the minimum crystallite size from 17 to 4 nm. This difference increases the number of grain boundary atoms from 12% to 40% which could augment the anti-inflammatory properties of the dressings. The formation of gold oxide (Au2O3) was thought to be responsible for the observed decrease in crystallite size.

  10. Peroxide-based oxygen generating topical wound dressing for enhancing healing of dermal wounds.

    PubMed

    Chandra, Prafulla K; Ross, Christina L; Smith, Leona C; Jeong, Seon S; Kim, Jaehyun; Yoo, James J; Harrison, Benjamin S

    2015-01-01

    Oxygen generating biomaterials represent a new trend in regenerative medicine that aims to generate and supply oxygen at the site of requirement, to support tissue healing and regeneration. To enhance the healing of dermal wounds, we have developed a highly portable, in situ oxygen generating wound dressings that uses sodium percarbonate (SPO) and calcium peroxide (CPO) as chemical oxygen sources. The dressing continuously generated oxygen for more than 3 days, after which it was replaced. In the in vivo testing on porcine full-thickness porcine wound model, the SPO/CPO dressing showed enhanced wound healing during the 8 week study period. Quantitative measurements of wound healing related parameters, such as wound closure, reepithelialization, epidermal thickness and collagen content of dermis showed that supplying oxygen topically using the SPO/CPO dressing significantly accelerated the wound healing. An increase in neovascularization, as determined using Von Willebrand factor (vWF) and CD31 staining, was also observed in the presence of SPO/CPO dressing. This novel design for a wound dressing that contains oxygen generating biomaterials (SPO/CPO) for supplying topical oxygen, may find utility in treating various types of acute to chronic wounds.

  11. Striking individual differences in color perception uncovered by 'the dress' photograph.

    PubMed

    Lafer-Sousa, Rosa; Hermann, Katherine L; Conway, Bevil R

    2015-06-29

    'The dress' is a peculiar photograph: by themselves the dress' pixels are brown and blue, colors associated with natural illuminants, but popular accounts (#TheDress) suggest the dress appears either white/gold or blue/black. Could the purported categorical perception arise because the original social-media question was an alternative-forced-choice? In a free-response survey (N = 1401), we found that most people, including those naïve to the image, reported white/gold or blue/black, but some said blue/brown. Reports of white/gold over blue/black were higher among older people and women. On re-test, some subjects reported a switch in perception, showing the image can be multistable. In a language-independent measure of perception, we asked subjects to identify the dress' colors from a complete color gamut. The results showed three peaks corresponding to the main descriptive categories, providing additional evidence that the brain resolves the image into one of three stable percepts. We hypothesize that these reflect different internal priors: some people favor a cool illuminant (blue sky), discount shorter wavelengths, and perceive white/gold; others favor a warm illuminant (incandescent light), discount longer wavelengths, and see blue/black. The remaining subjects may assume a neutral illuminant, and see blue/brown. We show that by introducing overt cues to the illumination, we can flip the dress color. PMID:25981795

  12. Transient absorption and reshaping of ultrafast XUV light by laser-dressed helium

    SciTech Connect

    Gaarde, Mette B.; Schafer, Kenneth J.; Buth, Christian; Tate, Jennifer L.

    2011-01-15

    We present a theoretical study of transient absorption and reshaping of extreme ultraviolet (XUV) pulses by helium atoms dressed with a moderately strong infrared (IR) laser field. We formulate the atomic response using both the frequency-dependent absorption cross section and a time-frequency approach based on the time-dependent dipole induced by the light fields. The latter approach can be used in cases when an ultrafast dressing pulse induces transient effects, and/or when the atom exchanges energy with multiple frequency components of the XUV field. We first characterize the dressed atom response by calculating the frequency-dependent absorption cross section for XUV energies between 20 and 24 eV for several dressing wavelengths between 400 and 2000 nm and intensities up to 10{sup 12} W/cm{sup 2}. We find that for dressing wavelengths near 1600 nm, there is an Autler-Townes splitting of the 1s{yields}2p transition that can potentially lead to transparency for absorption of XUV light tuned to this transition. We study the effect of this XUV transparency in a macroscopic helium gas by incorporating the time-frequency approach into a solution of the coupled Maxwell-Schroedinger equations. We find rich temporal reshaping dynamics when a 61-fs XUV pulse resonant with the 1s{yields}2p transition propagates through a helium gas dressed by an 11-fs, 1600-nm laser pulse.

  13. Observations of λ /4 structure in a low-loss radio-frequency-dressed optical lattice

    NASA Astrophysics Data System (ADS)

    Lundblad, N.; Ansari, S.; Guo, Y.; Moan, E.

    2014-11-01

    We load a Bose-Einstein condensate into a one-dimensional (1D) optical lattice altered through the use of radio-frequency (rf) dressing. The rf resonantly couples the three levels of the 87Rb F =1 manifold and combines with a spin-dependent "bare" optical lattice to result in adiabatic potentials of variable shape, depth, and spatial frequency content. We choose dressing parameters such that the altered lattice is stable over lifetimes exceeding tens of ms at higher depths than in previous work. We observe significant differences between the BEC momentum distributions of the dressed lattice as compared to the bare lattice, and find general agreement with a 1D band-structure calculation informed by the dressing parameters. Previous work using such lattices was limited by very shallow dressed lattices and strong Landau-Zener tunneling loss between adiabatic potentials, equivalent to failure of the adiabatic criterion. In this work we operate with significantly stronger rf coupling (increasing the avoided-crossing gap between adiabatic potentials), observing dressed lifetimes of interest for optical lattice-based analog solid-state physics.

  14. The effect of Ringer's solution within a dressing to elicit pain relief.

    PubMed

    Colegrave, M; Rippon, M G; Richardson, C

    2016-04-01

    Clinical studies suggest that dressings containing Ringer's solution, such as the TenderWet and HydroClean families, provide relief from wound pain. This report reviews the available evidence and possible mechanisms for the relief of wound pain by these dressings. The ability of dressings containing Ringer's solution to provide pain relief is likely to be through providing a moist environment that is favourable for wound healing; furthermore, the dressing augments the protective barrier function by having additional fluid under the dressing, which covers exposed nerve endings and protects against friction damage. Ringer's solution will have a dilution effect and an influence on the pH of exudate. Diluting cytokines within the exudate would be expected to decrease inflammation in chronic wounds and reduce the influence of caustic components such as matrix metalloproteases (MMPs). Altering the pH of the wound bed could inactivate proteins and glycoproteins implicated in the pain response such as MMPs and sodium and calcium channels. The moist environment may also be better at recruiting leukocytes that release natural painkillers at areas of injury. These mechanisms are likely to act in combination to explain why dressings containing Ringer's solution can have analgesic effects. PMID:27064367

  15. The Controlled Induction of Distributed Microdeformation in Wounded Tissue via a Microchamber Array Dressing

    PubMed Central

    Kane, Bartholomew J.; Younan, George; Helm, Douglas; Dastouri, Pouya; Prentice-Mott, Harrison; Irimia, Daniel; Chan, Rodney K.; Toner, Mehmet; Orgill, Dennis P.

    2010-01-01

    Mechanical stimuli are known to play an important role in determining the structure and function of living cells and tissues. Recent studies have highlighted the role of mechanical signals in mammalian dermal wound healing. However, the biological link between mechanical stimulation of wounded tissue and the subsequent cellular response has not been fully determined. The capacity for researchers to study this link is partially limited by the lack of instrumentation capable of applying controlled mechanical stimuli to wounded tissue. The studies outlined here tested the hypothesis that it was possible to control the magnitude of induced wound tissue deformation using a microfabricated dressing, comprised of an array of open-faced, hexagonally-shaped microchambers rendered in a patch of silicone rubber. By connecting the dressing to a single vacuum source, the underlying wounded tissue was drawn up into each of the microchambers, thereby inducing tissue deformation. For these studies, the dressings were applied to full thickness murine dermal wounds with 200 mmHg vacuum for 12 hours. The studies demonstrated that the dressing was capable of inducing wound tissue deformation with values ranging from 11 to 29 %. Through statistical analysis, the magnitude of the induced deformation was shown to be a function of both microchamber height and width. These results demonstrated that the dressing was capable of controlling the amount of deformation imparted in the underlying tissue. By allowing the application of mechanical stimulation with varying intensity, such a dressing will enable the performance of sophisticated mechanobiology studies in dermal wound healing. PMID:20607869

  16. Egg white/poly (vinyl alcohol)/MMT nanocomposite hydrogels for wound dressing.

    PubMed

    Jahani-Javanmardi, Azinsadat; Sirousazar, Mohammad; Shaabani, Yasaman; Kheiri, Farshad

    2016-08-01

    Nanocomposite hydrogels on the basis of egg white and poly (vinyl alcohol) (PVA) containing 0, 5, and 10 wt.% of montmorillonite (MMT) nanoclay were prepared by a facile cyclic freezing-thawing technique and their properties investigated for wound dressing application. The morphological, structural, thermal, physical, and in vitro cytotoxic properties of the prepared nanocomposite hydrogel wound dressings (NHWDs) were experimentally studied. The NHWDs had an exfoliated morphology with a porous structure having pores sizes in the nanometric scale. It was shown that MMT acted as cross-linker in the network of NHWDs and improved their thermal stabilities. The prepared wound dressings were transparent and their equilibrium water contents and water vapor transmission rates, as two important factors of wound dressings, were very close to the properties of human skin which means that the prepared wound dressings could interact appropriately with the damaged tissues of wounds and protect them like an artificial skin during the wound healing process. The in vitro cytotoxicity assay also confirmed the non-cytotoxic nature of the prepared NHWDs. It was finally concluded that the prepared egg white/PVA/MMT nanocomposite hydrogels are promising materials to be used as novel wound dressings in wound and burn care. PMID:27193240

  17. DRESS Syndrome Caused by Cross-reactivity Between Vancomycin and Subsequent Teicoplanin Administration: A Case Report.

    PubMed

    Miyazu, Daisuke; Kodama, Nobuhiro; Yamashita, Daiki; Tanaka, Hirokazu; Inoue, Sachiko; Imakyure, Osamu; Hirakawa, Masaaki; Shuto, Hideki; Kataoka, Yasufumi

    2016-01-01

    BACKGROUND Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening syndrome comprising severe skin eruption, fever, eosinophilia, lymphadenopathy, and involvement of internal organs. Here, we describe a case of DRESS syndrome caused by cross-reactivity between vancomycin and subsequent teicoplanin administration. CASE REPORT A 79-year-old male was admitted to our hospital for the treatment of injuries incurred in a traffic accident. Eosinophilia and lung dysfunction appeared after vancomycin administration. These symptoms were improved temporarily by withdrawal of vancomycin and administration of corticosteroid, but exacerbated by subsequent teicoplanin administration. These symptoms disappeared after discontinuation of teicoplanin. Based on comprehensive assessment of the overall clinical course, we judged that DRESS syndrome was induced by cross-reactivity between vancomycin and subsequent teicoplanin administration. Using the European Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) scoring system, we categorized DRESS syndrome related to vancomycin and teicoplanin as "probable." We describe, for the first time, DRESS syndrome (defined using the RegiSCAR scoring system) caused by cross-reactivity between vancomycin and subsequent teicoplanin administration. CONCLUSIONS Clinicians should be aware that DRESS syndrome can be induced by cross-reactivity between vancomycin and teicoplanin. PMID:27572807

  18. Guanidine hydrochloride embedded polyurethanes as antimicrobial and absorptive wound dressing membranes with promising cytocompatibility.

    PubMed

    Sahraro, Maryam; Yeganeh, Hamid; Sorayya, Marziyeh

    2016-02-01

    Preparation and assessments of novel absorptive wound dressing materials with efficient antimicrobial activity as well as very good cytocompatibility were described in this work. An amine terminated poly(hexamethylene guanidine hydrochloride) was prepared and used as curing agent of different epoxy-terminated polyurethane prepolymers. The structures of prepared materials were elucidated by evaluation of their (1)H NMR and FTIR spectra. The recorded tensile strength of membranes confirmed the excellent dimensional stability of the film type dressings even at fully hydrated conditions. Therefore, these dressings could protect the wound bed from external forces during the healing period. The structurally optimized dressing membranes could preserve the desired moist environment over the wounded area, as a result of their balanced equilibrium, water absorption and water vapor transmission rate. Therefore, a very good condition for stimulation of self-healing of wound bed was attained. Also, owing to the presence of guanidine hydrochloride moieties embedded into the structure of dressings, efficient antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans were detected. In vitro cytotoxicity assay of the prepared dressings revealed cytocompatibility of these materials against fibroblast cells. Therefore, they could support cell growth and proliferation at the wounded area.

  19. Antimicrobial dressing efficacy against mature Pseudomonas aeruginosa biofilm on porcine skin explants.

    PubMed

    Phillips, Priscilla L; Yang, Qingping; Davis, Stephen; Sampson, Edith M; Azeke, John I; Hamad, Afifa; Schultz, Gregory S

    2015-08-01

    An ex vivo porcine skin explant biofilm model that preserves key properties of biofilm attached to skin at different levels of maturity (0-3 days) was used to assess the efficacy of commercially available antimicrobial dressings and topical treatments. Assays were also performed on the subpopulation of antibiotic tolerant biofilm generated by 24 hours of pre-treatment with gentamicin (120× minimal inhibitory concentration) prior to agent exposure. Five types of antimicrobial agents (iodine, silver, polyhexamethylene biguanide, honey and ethanol) and four types of moisture dressings (cotton gauze, sodium carboxymethylcellulose fibre, calcium alginate fibre and cadexomer beads) were assessed. Time-release silver gel and cadexomer iodine dressings were the most effective in reducing mature biofilm [between 5 and 7 logarithmic (log) of 7-log total], whereas all other dressing formulations reduced biofilm between 0·3 and 2 log in 24 or 72 hours with a single exposure. Similar results were found after 24-hour exposure to silver release dressings using an in vivo pig burn wound model, demonstrating correlation between the ex vivo and in vivo models. Results of this study indicate that commonly used microbicidal wound dressings vary widely in their ability to kill mature biofilm and the efficacy is influenced by time of exposure, number of applications, moisture level and agent formulation (sustained release).

  20. Randomized Comparison of Dry Dressings Versus Hydrogel in Management of Radiation-Induced Moist Desquamation

    SciTech Connect

    Macmillan, Maureen S. . E-mail: m.macmillan@napier.ac.uk; Wells, Mary; MacBride, Sheila; Raab, Gillian M.; Munro, Alastair; MacDougall, Hugh

    2007-07-01

    Purpose: We present the results of a randomized controlled clinical trial that evaluated the effect of a hydrogel or dry dressing on the time to healing of moist desquamation after radiotherapy to the head-and-neck, breast, or anorectal areas. Methods and Materials: A total of 357 patients were randomized before radiotherapy to receive simple dry dressings (Tricotex) or a hydrogel (Intrasite), with Tricotex as a secondary dressing. Patients were instructed to use their dressings from the onset of moist desquamation, if it occurred. Results: Of the 357 patients, 100 (28%) developed moist desquamation. The time to healing was significantly prolonged (hazard ratio, 0.64; 95% confidence interval, 0.42-0.99), in patients assigned to gel dressings. No evidence was found that gel dressings had a significant impact on subjectively reported skin symptoms. Conclusion: The results of this study have not supported the routine use of hydrogels in the care of patients with moist desquamation and suggests that the healing times are prolonged, without any improvement in patient comfort.

  1. Novel biodegradable composite wound dressings with controlled release of antibiotics: microstructure, mechanical and physical properties.

    PubMed

    Elsner, Jonathan J; Shefy-Peleg, Adaya; Zilberman, Meital

    2010-05-01

    Wound dressings aim to restore the milieu required for skin regeneration and protect the wound from environmental threats, including penetration of bacteria. The dressings should be easy to apply and remove and maintain a moist healing environment. In this study, novel biodegradable composite wound dressings based on a polyglyconate mesh and a porous PDLGA binding matrix were developed and studied. These novel dressings were prepared by dip-coating woven meshes in inverted emulsions, followed by freeze-drying. Their investigation focused on the microstructure, mechanical and physical properties, and the release profile of the antibiotic drug ceftazidime from the binding matrix. The mechanical properties of our wound-dressing structures were found to be superior, combining relatively high tensile strength and ductility, which changed only slightly during 3 weeks of incubation in an aqueous medium. The parameters of the inverted emulsion, the organic-aqueous phase ratio, and the type of surfactant used for stabilizing the emulsion were found to affect the microstructure of the binding matrix and the resulting properties, i.e., water absorbance, water vapor transmission rate, and drug-release profile from the binding matrix. Appropriate selection of these parameters can yield composite structures that have the desired physical properties and drug release behavior. Thus, these unique structures are potentially very useful as burn and ulcer dressings.

  2. Striking individual differences in color perception uncovered by 'the dress' photograph.

    PubMed

    Lafer-Sousa, Rosa; Hermann, Katherine L; Conway, Bevil R

    2015-06-29

    'The dress' is a peculiar photograph: by themselves the dress' pixels are brown and blue, colors associated with natural illuminants, but popular accounts (#TheDress) suggest the dress appears either white/gold or blue/black. Could the purported categorical perception arise because the original social-media question was an alternative-forced-choice? In a free-response survey (N = 1401), we found that most people, including those naïve to the image, reported white/gold or blue/black, but some said blue/brown. Reports of white/gold over blue/black were higher among older people and women. On re-test, some subjects reported a switch in perception, showing the image can be multistable. In a language-independent measure of perception, we asked subjects to identify the dress' colors from a complete color gamut. The results showed three peaks corresponding to the main descriptive categories, providing additional evidence that the brain resolves the image into one of three stable percepts. We hypothesize that these reflect different internal priors: some people favor a cool illuminant (blue sky), discount shorter wavelengths, and perceive white/gold; others favor a warm illuminant (incandescent light), discount longer wavelengths, and see blue/black. The remaining subjects may assume a neutral illuminant, and see blue/brown. We show that by introducing overt cues to the illumination, we can flip the dress color.

  3. Antibacterial hemostatic dressings with nanoporous bioglass containing silver

    PubMed Central

    Hu, Gangfeng; Xiao, Luwei; Tong, Peijian; Bi, Dawei; Wang, Hui; Ma, Haitao; Zhu, Gang; Liu, Hui

    2012-01-01

    Nanoporous bioglass containing silver (n-BGS) was fabricated using the sol-gel method, with cetyltrimethyl ammonium bromide as template. The results showed that n-BGS with nanoporous structure had a surface area of 467 m2/g and a pore size of around 6 nm, and exhibited a significantly higher water absorption rate compared with BGS without nanopores. The n-BGS containing small amounts of silver (Ag) had a slight effect on its surface area. The n-BGS containing 0.02 wt% Ag, without cytotoxicity, had a good antibacterial effect on Escherichia coli, and its antibacterial rate reached 99% in 12 hours. The n-BGS’s clotting ability significantly decreased prothrombin time (PT) and activated partial thromboplastin time (APTT), indicating n-BGS with a higher surface area could significantly promote blood clotting (by decreasing clotting time) compared with BGS without nanopores. Effective hemostasis was achieved in skin injury models, and bleeding time was reduced. It is suggested that n-BGS could be a good dressing, with antibacterial and hemostatic properties, which might shorten wound bleeding time and control hemorrhage. PMID:22745538

  4. Robust quantum logic in neutral atoms via adiabatic Rydberg dressing

    DOE PAGES

    Keating, Tyler; Cook, Robert L.; Hankin, Aaron M.; Jau, Yuan -Yu; Biedermann, Grant W.; Deutsch, Ivan H.

    2015-01-28

    We study a scheme for implementing a controlled-Z (CZ) gate between two neutral-atom qubits based on the Rydberg blockade mechanism in a manner that is robust to errors caused by atomic motion. By employing adiabatic dressing of the ground electronic state, we can protect the gate from decoherence due to random phase errors that typically arise because of atomic thermal motion. In addition, the adiabatic protocol allows for a Doppler-free configuration that involves counterpropagating lasers in a σ+/σ- orthogonal polarization geometry that further reduces motional errors due to Doppler shifts. The residual motional error is dominated by dipole-dipole forces actingmore » on doubly-excited Rydberg atoms when the blockade is imperfect. As a result, for reasonable parameters, with qubits encoded into the clock states of 133Cs, we predict that our protocol could produce a CZ gate in < 10 μs with error probability on the order of 10-3.« less

  5. Revealing dressed quarks via the proton's charge distribution.

    PubMed

    Cloët, Ian C; Roberts, Craig D; Thomas, Anthony W

    2013-09-01

    The proton is arguably the most fundamental of nature's readily detectable building blocks. It is at the heart of every nucleus and has never been observed to decay. It is nevertheless a composite object, defined by its valence-quark content: u+u+d--i.e., two up (u) quarks and one down (d) quark; and the manner by which they influence, inter alia, the distribution of charge and magnetization within this bound state. Much of novelty has recently been learned about these distributions; and it now appears possible that the proton's momentum-space charge distribution possesses a zero. Experiments in the coming decade should answer critical questions posed by this and related advances; we explain how such new information may assist in charting the origin and impact of key emergent phenomena within the strong interaction. Specifically, we show that the possible existence and location of a zero in the proton's electric form factor are a measure of nonperturbative features of the quark-quark interaction in the standard model, with particular sensitivity to the running of the dressed-quark mass.

  6. Robust quantum logic in neutral atoms via adiabatic Rydberg dressing

    SciTech Connect

    Keating, Tyler; Cook, Robert L.; Hankin, Aaron M.; Jau, Yuan -Yu; Biedermann, Grant W.; Deutsch, Ivan H.

    2015-01-28

    We study a scheme for implementing a controlled-Z (CZ) gate between two neutral-atom qubits based on the Rydberg blockade mechanism in a manner that is robust to errors caused by atomic motion. By employing adiabatic dressing of the ground electronic state, we can protect the gate from decoherence due to random phase errors that typically arise because of atomic thermal motion. In addition, the adiabatic protocol allows for a Doppler-free configuration that involves counterpropagating lasers in a σ+- orthogonal polarization geometry that further reduces motional errors due to Doppler shifts. The residual motional error is dominated by dipole-dipole forces acting on doubly-excited Rydberg atoms when the blockade is imperfect. As a result, for reasonable parameters, with qubits encoded into the clock states of 133Cs, we predict that our protocol could produce a CZ gate in < 10 μs with error probability on the order of 10-3.

  7. Multifunctional medicated lyophilised wafer dressing for effective chronic wound healing.

    PubMed

    Pawar, Harshavardhan V; Boateng, Joshua S; Ayensu, Isaac; Tetteh, John

    2014-06-01

    Wafers combining weight ratios of Polyox with carrageenan (75/25) or sodium alginate (50/50) containing streptomycin and diclofenac were prepared to improve chronic wound healing. Gels were freeze-dried using a lyophilisation cycle incorporating an annealing step. Wafers were characterised for morphology, mechanical and in vitro functional (swelling, adhesion, drug release in the presence of simulated wound fluid) characteristics. Both blank (BLK) and drug-loaded (DL) wafers were soft, flexible, elegant in appearance and non-brittle in nature. Annealing helped to improve porous nature of wafers but was affected by the addition of drugs. Mechanical characterisation demonstrated that the wafers were strong enough to withstand normal stresses but also flexible to prevent damage to newly formed skin tissue. Differences in swelling, adhesion and drug release characteristics could be attributed to differences in pore size and sodium sulphate formed because of the salt forms of the two drugs. BLK wafers showed relatively higher swelling and adhesion than DL wafers with the latter showing controlled release of streptomycin and diclofenac. The optimised dressing has the potential to reduce bacterial infection and can also help to reduce swelling and pain associated with injury due to the anti-inflammatory action of diclofenac and help to achieve more rapid wound healing.

  8. Antioxidant capacity of vegetables, spices and dressings relevant to nutrition.

    PubMed

    Ninfali, Paolino; Mea, Gloria; Giorgini, Samantha; Rocchi, Marco; Bacchiocca, Mara

    2005-02-01

    Vegetables are the most important sources of phenolics in the Mediterranean diet. Phenolics, especially flavonoids, are suggested as being essential bioactive compounds providing health benefits. In this study, twenty-seven vegetables, fifteen aromatic herbs and some spices consumed in Central Italy (the Marches region) were studied to reveal total phenolic, flavonoid and flavanol content as well as their antioxidant capacity measured by the oxygen radical absorbance capacity (ORAC) method. A comparison in terms of antioxidant capacity was made between different salads, as well as between salads to which aromatic herbs had been added. Lemon balm and marjoram at a concentration of 1.5 % w/w increased by 150 % and 200 % respectively the antioxidant capacity of a salad portion. A 200 g portion of a salad enriched with marjoram corresponded to an intake of 200 (SD 10) mg phenolics and 4000 (SD 300) ORAC units (micromol Trolox equivalents). Olive oils and wine or apple vinegars were the salad dressings that provided the highest increase in antioxidant capacity. Among the spices tested, cumin and fresh ginger made the most significant contribution to the antioxidant capacity. The results are useful in surveying the antioxidant parameters of vegetables, herbs and spices produced and consumed in our geographical area as well as in quantifying the daily intake of phenolics and ORAC units. The results can be used in public health campaigns to stimulate the consumption of vegetables able to provide significant health protection in order to prevent chronic diseases.

  9. Alginate hydrogels coated with chitosan for wound dressing.

    PubMed

    Straccia, Maria Cristina; d'Ayala, Giovanna Gomez; Romano, Ida; Oliva, Adriana; Laurienzo, Paola

    2015-05-11

    In this work, a coating of chitosan onto alginate hydrogels was realized using the water-soluble hydrochloride form of chitosan (CH-Cl), with the dual purpose of imparting antibacterial activity and delaying the release of hydrophilic molecules from the alginate matrix. Alginate hydrogels with different calcium contents were prepared by the internal setting method and coated by immersion in a CH-Cl solution. Structural analysis by cryo-scanning electron microscopy was carried out to highlight morphological alterations due to the coating layer. Tests in vitro with human mesenchymal stromal cells (MSC) were assessed to check the absence of toxicity of CH-Cl. Swelling, stability in physiological solution and release characteristics using rhodamine B as the hydrophilic model drug were compared to those of relative uncoated hydrogels. Finally, antibacterial activity against Escherichia coli was tested. Results show that alginate hydrogels coated with chitosan hydrochloride described here can be proposed as a novel medicated dressing by associating intrinsic antimicrobial activity with improved sustained release characteristics.

  10. Nanolayered siRNA dressing for sustained localized knockdown.

    PubMed

    Castleberry, Steven; Wang, Mary; Hammond, Paula T

    2013-06-25

    The success of RNA interference (RNAi) in medicine relies on the development of technology capable of successfully delivering it to tissues of interest. Significant research has focused on the difficult task of systemic delivery of RNAi; however its local delivery could be a more easily realized approach. Localized delivery is of particular interest for many medical applications, including the treatment of localized diseases, the modulation of cellular response to implants or tissue engineering constructs, and the management of wound healing and regenerative medicine. In this work we present an ultrathin electrostatically assembled coating for localized and sustained delivery of short interfering RNA (siRNA). This film was applied to a commercially available woven nylon dressing commonly used for surgical applications and was demonstrated to sustain significant knockdown of protein expression in multiple cell types for more than one week in vitro. Significantly, this coating can be easily applied to a medically relevant device and requires no externally delivered transfection agents for effective delivery of siRNA. These results present promising opportunities for the localized administration of RNAi. PMID:23672676

  11. Ion-acoustic dressed solitons in a dusty plasma

    SciTech Connect

    Tiwari, R.S.; Mishra, M.K.

    2006-06-15

    Using the reductive perturbation method, equations for ion-acoustic waves governing the evolution of first- and second-order potentials in a dusty plasma including the dynamics of charged dust grains have been derived. The renormalization procedure of Kodama and Taniuti is used to obtain a steady state nonsecular solution of these equations. The variation of velocity and width of the Korteweg-de Vries (KdV) as well as dressed solitons with amplitude have been studied for different concentrations and charge multiplicity of dust grains. The higher-order perturbation corrections to the KdV soliton description significantly affect the characteristics of the solitons in dusty plasma. It is found that in the presence of positively charged dust grains the system supports only compressive solitons. However, the plasma with negatively charged dust grains can support compressive solitons only up to a certain concentration of dust. Above this critical concentration of negative charge, the dusty plasma can support rarefactive solitons. An expression for the critical concentration of negatively charged dust in terms of charge and mass ratio of dust grains with plasma ions is also derived.

  12. Dressing and Hair-Styling Virtual Characters from a Sketch

    NASA Astrophysics Data System (ADS)

    Wither, Jamie; Cani, Marie-Paule

    This chapter presents a different use of sketch-based modeling, namely the modeling of complex objects from a single sketch, illustrated by the examples of dressing and hairstyling a virtual character. Knowing the nature of the object being modeled eases the extraction of information from a sketch, so that a single sketch depicting a front view (and optionally a second one from the back or side) is sufficient to specify these complex 3D shapes. We show how different levels of prior knowledge about the object being modeled, from basic rules of thumb to more intricate geometric or physically based properties, can be used to interpret the sketch strokes and to infer the missing 3D information, leading to different degrees of visual realism. In addition to discussing practical solutions for the sketch-based modeling of garments and hair that save several orders of magnitude of user time compared to standard 3D modeling methods, this chapter provides the basis of a general methodology towards the design of sketch-based interfaces for complex models.

  13. Alginate Hydrogels Coated with Chitosan for Wound Dressing

    PubMed Central

    Straccia, Maria Cristina; Gomez d’Ayala, Giovanna; Romano, Ida; Oliva, Adriana; Laurienzo, Paola

    2015-01-01

    In this work, a coating of chitosan onto alginate hydrogels was realized using the water-soluble hydrochloride form of chitosan (CH-Cl), with the dual purpose of imparting antibacterial activity and delaying the release of hydrophilic molecules from the alginate matrix. Alginate hydrogels with different calcium contents were prepared by the internal setting method and coated by immersion in a CH-Cl solution. Structural analysis by cryo-scanning electron microscopy was carried out to highlight morphological alterations due to the coating layer. Tests in vitro with human mesenchymal stromal cells (MSC) were assessed to check the absence of toxicity of CH-Cl. Swelling, stability in physiological solution and release characteristics using rhodamine B as the hydrophilic model drug were compared to those of relative uncoated hydrogels. Finally, antibacterial activity against Escherichia coli was tested. Results show that alginate hydrogels coated with chitosan hydrochloride described here can be proposed as a novel medicated dressing by associating intrinsic antimicrobial activity with improved sustained release characteristics. PMID:25969981

  14. Dressings and drains in posterior spine surgery and their effect on wound complications.

    PubMed

    Andrew Glennie, R; Dea, Nicolas; Street, John T

    2015-07-01

    The purpose of this study was to systematically search, critically appraise and summarize published randomized control trials (RCT) and non-RCT examining the effect of drains and dressings on wound healing rates and complications in posterior spine surgery. The use of post-operative drains and the type of post-operative dressing is at the discretion of the treating surgeon with no available clinical guidelines. Drains will theoretically decrease incidence of post-operative hematoma and therefore, potentially decrease the risk of neurologic compromise when the neural elements have been exposed. Occlusive dressings have more recently been advocated, potentially maintaining a sterile barrier for longer time periods post-operatively. A systematic review of databases from 1969-2013 was undertaken. All papers examining drains in spine surgery and dressings in primary healing of surgical wounds were included. Revman (version 5.2; The Nordic Cochrane Centre, The Cochrane Collaboration, Oxford, UK) was used to test for overall treatment effect, clinical heterogeneity and risk of bias. Of the papers identified, 1348 examined post-operative drains in spine surgery and 979 wound dressings for primary wound healing of all surgical wounds. Seven studies were included for analysis for post-operative drains and 10 studies were analyzed for primary wound healing. The use of a post-operative drain did not influence healing rates and had no effect secondarily on infection (odds ratio [OR] 1.33; 95% confidence interval [CI] 0.76-2.30). We were not able to establish whether surgical drains prevent hematomas causing neurologic compromise. There was a slight advantage to using occlusive dressings versus non-occlusive dressings in wound healing (OR 2.09; 95% CI 1.44-3.02). Incisional vacuum dressings as both an occlusive barrier and superficial drainage system have shown promise for wounds at risk of dehiscence. There is a relatively high risk of bias in the methodology of many of the

  15. Performance of an in situ formed bioactive hydrogel dressing from a PEG-based hyperbranched multifunctional copolymer.

    PubMed

    Dong, Yixiao; Hassan, Waqar U; Kennedy, Robert; Greiser, Udo; Pandit, Abhay; Garcia, Yolanda; Wang, Wenxin

    2014-05-01

    Hydrogel dressings have been widely used for wound management due to their ability to maintain a hydrated wound environment, restore the skin's physical barrier and facilitate regular dressing replacement. However, the therapeutic functions of standard hydrogel dressings are restricted. In this study, an injectable hybrid hydrogel dressing system was prepared from a polyethylene glycol (PEG)-based thermoresponsive hyperbranched multiacrylate functional copolymer and thiol-modified hyaluronic acid in combination with adipose-derived stem cells (ADSCs). The cell viability, proliferation and metabolic activity of the encapsulated ADSCs were studied in vitro, and a rat dorsal full-thickness wound model was used to evaluate this bioactive hydrogel dressing in vivo. It was found that long-term cell viability could be achieved for both in vitro (21days) and in vivo (14days) studies. With ADSCs, this hydrogel system prevented wound contraction and enhanced angiogenesis, showing the potential of this system as a bioactive hydrogel dressing for wound healing.

  16. Performance of an in situ formed bioactive hydrogel dressing from a PEG-based hyperbranched multifunctional copolymer.

    PubMed

    Dong, Yixiao; Hassan, Waqar U; Kennedy, Robert; Greiser, Udo; Pandit, Abhay; Garcia, Yolanda; Wang, Wenxin

    2014-05-01

    Hydrogel dressings have been widely used for wound management due to their ability to maintain a hydrated wound environment, restore the skin's physical barrier and facilitate regular dressing replacement. However, the therapeutic functions of standard hydrogel dressings are restricted. In this study, an injectable hybrid hydrogel dressing system was prepared from a polyethylene glycol (PEG)-based thermoresponsive hyperbranched multiacrylate functional copolymer and thiol-modified hyaluronic acid in combination with adipose-derived stem cells (ADSCs). The cell viability, proliferation and metabolic activity of the encapsulated ADSCs were studied in vitro, and a rat dorsal full-thickness wound model was used to evaluate this bioactive hydrogel dressing in vivo. It was found that long-term cell viability could be achieved for both in vitro (21days) and in vivo (14days) studies. With ADSCs, this hydrogel system prevented wound contraction and enhanced angiogenesis, showing the potential of this system as a bioactive hydrogel dressing for wound healing. PMID:24389319

  17. A comparative study between honey and povidone iodine as dressing solution for Wagner type II diabetic foot ulcers.

    PubMed

    Shukrimi, A; Sulaiman, A R; Halim, A Y; Azril, A

    2008-03-01

    Honey dressing has been used to promote wound healing for years but scanty scientific studies did not provide enough evidences to justify it benefits in the treatment of diabetic foot ulcers. We conducted a prospective study to compare the effect of honey dressing for Wagner's grade-II diabetic foot ulcers with controlled dressing group (povidone iodine followed by normal saline). Surgical debridement and appropriate antibiotics were prescribed in all patients. There were 30 patients age between 31 to 65-years-old (mean of 52.1 years). The mean healing time in the standard dressing group was 15.4 days (range 9-36 days) compared to 14.4 days (range 7-26 days) in the honey group (p < 0.005). In conclusion, ulcer healing was not significantly different in both study groups. Honey dressing is a safe alternative dressing for Wagner grade-II diabetic foot ulcers. PMID:18935732

  18. A prospective, randomized clinical trial to assess the cost-effectiveness of a modern foam dressing versus a traditional saline gauze dressing in the treatment of stage II pressure ulcers.

    PubMed

    Payne, Wyatt G; Posnett, John; Alvarez, Oscar; Brown-Etris, Marie; Jameson, Gayle; Wolcott, Randall; Dharma, Hussein; Hartwell, Samantha; Ochs, Diane

    2009-02-01

    Modern dressings such as hydrocolloids, gels, and foams are typically more expensive than traditional dressings such as gauze. However, if modern dressings require fewer changes, the overall cost of treatment may be lower despite the higher initial purchase price. If healing rates are comparable or better, modern dressings also may be cost-effective. A 4-week, prospective, randomized clinical trial to assess differences in treatment costs and cost-effectiveness between a modern foam dressing and saline-soaked gauze was conducted among 36 patients (22 men, 14 women, mean age 72.8 years) with a Stage II pressure ulcer (mean duration 35 weeks) at five centers in the United States. Participants were randomized to treatment with a self-adhesive polyurethane foam (n = 20) or saline-soaked gauze dressing (n = 16). No difference in time to wound closure was observed (P = 0.817). Patients in the foam group had less frequent dressing changes (P <0.001). Total cost over the study period was lower by $466 per patient (P = 0.055) and spending on dressings was lower by $92 per patient in the foam group (P = 0.025). Cost per ulcer healed was lower by $1,517 and cost per ulcer-free day was lower by $80 for patients in the foam group. On the evidence of this study, the foam dressing is a more cost-effective treatment than saline-soaked gauze for the treatment of Stage II pressure ulcers.

  19. Electrospun zwitterionic poly(sulfobetaine methacrylate) for nonadherent, superabsorbent, and antimicrobial wound dressing applications.

    PubMed

    Lalani, Reza; Liu, Lingyun

    2012-06-11

    Zwitterionic poly(sulfobetaine methacrylate) (PSBMA) has been well studied for its superhydrophilic and ultralow biofouling properties, making it a promising material for superabsorbent and nonadherent wound dressings. Electrospinning provides multiple desirable features for wound dressings, including high absorptivity due to high surface-area-to-volume ratio, high gas permeation, and conformability to contour of the wound bed. The goal of this work is to develop a fibrous membrane of PSBMA via electrospinning and evaluate its properties related to wound dressing applications. Being superhydrophilic, PSBMA fibers fabricated by a conventional electrospinning method would readily dissolve in water, whereas if cross-linker is added, the formation of hydrogel would prevent electrospinning. A three-step polymerization-electrospinning-photo-cross-linking process was developed in this work to fabricate the cross-linked electrospun PSBMA fibrous membrane. Such electrospun membrane was stable in water and exhibited high water absorption of 353% (w/w), whereas the PSBMA hydrogel only absorbed 81% water. The electrospun membrane showed strong resistance to protein adsorption and cell attachment. Bacterial adhesion studies using Gram negative P. aeruginosa and Gram positive S. epidermidis showed that the PSBMA electrospun membrane was also highly resistant to bacterial adhesion. The Ag(+)-impregnated electrospun PSBMA membrane was shown microbicidal, against both S. epidermidis and P. aeruginosa. Such electrospun PSBMA membrane is ideal for a novel type of nonadherent, superabsorbent, and antimicrobial wound dressing. The superior water absorption aids in fluid removal from highly exudating wounds while keeping the wound hydrated to support healing. Because of the resistance to protein, cell, and bacterial adhesion, the dressing removal will neither cause patients' pain nor disturb the newly formed tissues. The dressing also prevents the attachment of environmental bacteria

  20. Electrospun zwitterionic poly(sulfobetaine methacrylate) for nonadherent, superabsorbent, and antimicrobial wound dressing applications.

    PubMed

    Lalani, Reza; Liu, Lingyun

    2012-06-11

    Zwitterionic poly(sulfobetaine methacrylate) (PSBMA) has been well studied for its superhydrophilic and ultralow biofouling properties, making it a promising material for superabsorbent and nonadherent wound dressings. Electrospinning provides multiple desirable features for wound dressings, including high absorptivity due to high surface-area-to-volume ratio, high gas permeation, and conformability to contour of the wound bed. The goal of this work is to develop a fibrous membrane of PSBMA via electrospinning and evaluate its properties related to wound dressing applications. Being superhydrophilic, PSBMA fibers fabricated by a conventional electrospinning method would readily dissolve in water, whereas if cross-linker is added, the formation of hydrogel would prevent electrospinning. A three-step polymerization-electrospinning-photo-cross-linking process was developed in this work to fabricate the cross-linked electrospun PSBMA fibrous membrane. Such electrospun membrane was stable in water and exhibited high water absorption of 353% (w/w), whereas the PSBMA hydrogel only absorbed 81% water. The electrospun membrane showed strong resistance to protein adsorption and cell attachment. Bacterial adhesion studies using Gram negative P. aeruginosa and Gram positive S. epidermidis showed that the PSBMA electrospun membrane was also highly resistant to bacterial adhesion. The Ag(+)-impregnated electrospun PSBMA membrane was shown microbicidal, against both S. epidermidis and P. aeruginosa. Such electrospun PSBMA membrane is ideal for a novel type of nonadherent, superabsorbent, and antimicrobial wound dressing. The superior water absorption aids in fluid removal from highly exudating wounds while keeping the wound hydrated to support healing. Because of the resistance to protein, cell, and bacterial adhesion, the dressing removal will neither cause patients' pain nor disturb the newly formed tissues. The dressing also prevents the attachment of environmental bacteria

  1. Hierarchy of Dysfunction Related to Dressing Performance in Stroke Patients: A Path Analysis Study

    PubMed Central

    Fujita, Takaaki; Nagayama, Hirofumi; Sato, Atsushi; Yamamoto, Yuichi; Yamane, Kazuhiro; Otsuki, Koji; Tsuchiya, Kenji; Tozato, Fusae

    2016-01-01

    Previous reports indicated that various dysfunctions caused by stroke affect the level of independence in dressing. These dysfunctions can be hierarchical, and these effects on dressing performance can be complicated in stroke patients. However, there are no published reports focusing on the hierarchical structure of the relationships between the activities of daily living and balance function, motor and sensory functions of the affected lower limb, strength of the abdominal muscles and knee extension on the unaffected side, and visuospatial deficits. The purpose of this study was to elucidate the hierarchical and causal relationships between dressing performance and these dysfunctions in stroke patients. This retrospective study included 104 first-time stroke patients. The causal relationship between the dressing performance and age, time post stroke, balance function, motor and sensory functions of the affected lower limb, strength of the abdominal muscles and knee extension on the unaffected side, and visuospatial deficits were examined using path analysis. A hypothetical path model was created based on previous studies, and the goodness of fit between the data and model were verified. A modified path model was created that achieved an almost perfect fit to the data. Balance function and abdominal muscle strength have direct effects on dressing performance, with standardized direct effect estimates of 0.78 and 0.15, respectively. Age, motor and sensory functions of the affected lower limb, and strength of abdominal muscle and knee extension on the unaffected side have indirect effects on dressing by influencing balance function. Our results suggest that dressing performance depends strongly on balance function, and it is mainly influenced by the motor function of the affected lower limb. PMID:26954499

  2. Visualisation of bacterial sequestration and bactericidal activity within hydrating Hydrofiber wound dressings.

    PubMed

    Newman, Geoffrey R; Walker, Michael; Hobot, Jan A; Bowler, Philip G

    2006-03-01

    The fluid handling and microbiological properties of a non-antimicrobial Hydrofiber(NAH) wound dressing have been compared with those of a silver salt-containing Hydrofiber (SCH). Fluorescent dyes (BacLight, Live/Dead Kit) were added to fresh cultures of two wound pathogens (Pseudomonas aeruginosa and Staphylococcus aureus), and used to visualise their viability. Live bacteria stained green and dead/dying bacteria turned red. When inoculated into samples of the NAH and SCH dressings, the viability of the bacteria could be effectively monitored over time using a rapid form of confocal laser scanning microscopy (RCLSM--Leica UK). When the NAH dressing was hydrated with stained bacterial culture, its fibres swelled quickly, reducing interstitial spaces between the fibres, resulting in the formation of a cohesive gel. Bacteria became immobilised in the gel, forming characteristic clumps, but remained largely green (viable) for more than 20 h with no apparent increase in numbers. The SCH initially behaved in a similar manner, however, using 3-D data from RCLSM time-lapse sequences P. aeruginosa was observed to turn progressively red (i.e. died) within 1.5-3 h and S. aureus similarly turned red within 5-7 h of contact with the SCH dressing. The ability of both Hydrofiber dressings to sequester and immobilise potentially pathogenic wound micro-organisms has been demonstrated. Additionally the SCH dressing was shown to kill immobilised bacteria, as a consequence of the ionic silver bactericide. These properties of the Hydrofiber dressings may contribute to providing an environment that is supportive to wound healing.

  3. Evaluation of a bi-layer wound dressing for burn care. II. In vitro and in vivo bactericidal properties.

    PubMed

    Martineau, Lucie; Shek, Pang N

    2006-03-01

    We have recently designed a medicated bi-layer wound dressing to address the key requirements for treating external, contaminated war wounds. This study assessed the in vitro and in vivo bactericidal efficacies of the DRDC hydrogel/polyurethane wound dressing. Chloramphenicol- and chlorhexidine-loaded DRDC dressings produced significantly larger zones of inhibition against Pseudomonas aeruginosa than the other medicated dressings for 4 d. Chlorhexidine-loaded Allevyn and Hydrasorb remained bactericidal for 48 h only. Chloramphenicol-loaded Hydrasorb and Allevyn remained bactericidal for 1 and 3 d, respectively. Ps. aeruginosa and Staphylococcus epidermidis counts in wounds treated with chlorhexidine- and chloramphenicol-loaded DRDC dressings for 24 h were 1-3-log lower than those of control wounds. While Ps. aeruginosa counts in the wounds on day 4 were comparable following daily changes of either antiseptic-loaded dressings, chlorhexidine showed a 75% greater bactericidal efficacy against Staph. epidermidis than chloramphenicol. Though increasing the frequency of dressing changes led to a greater reduction in the wound bacterial load, the contamination levels of all antiseptic-treated wounds remained below 10(5) CFU/g of wound. Cerium nitrate-loaded dressings did not exert any bactericidal effect, irrespective of the experimental conditions. These data show that the DRDC dressing is effective in delivering medications, such as an antimicrobial agent, to the wound bed. PMID:16455202

  4. Impact of silver-containing wound dressings on bacterial biofilm viability and susceptibility to antibiotics during prolonged treatment.

    PubMed

    Kostenko, Victoria; Lyczak, Jeffrey; Turner, Katherine; Martinuzzi, Robert John

    2010-12-01

    The long-term antimicrobial efficacy of silver dressings against bacterial biofilms was investigated in a 7-day treatment in vitro model where the protein-rich medium was refreshed daily in order to mimic the conditions found in a wound bed. The use of plate-to-plate transfer assays demonstrated measurable differences in the effectiveness of several silver dressings on the viability of biofilm bacteria and their susceptibility to antibiotics. Whereas after the first day of treatment, all dressings used resulted in a significant reduction in the number of viable cells in the biofilms and disruption of the biofilm colonies, during prolonged treatment, the efficacy of dressings with hydrophilic base materials diminished with daily transfers, and bacterial populations recovered. For dressings with hydrophobic base materials, the level of efficacy correlated with the silver species loaded. Biofilm bacteria, which survived the initial silver treatment, were susceptible to tobramycin, ciprofloxacin, and trimethoprim-sulfamethoxazole, in contrast to untreated biofilms, which were highly tolerant to the same antibiotics. This acquired susceptibility was unaffected by the longevity of pretreatment with the silver dressings but depended on the dressing used. The antimicrobial efficacy of the dressings correlated with the type of the dressing base material and silver species loaded.

  5. Agar/collagen membrane as skin dressing for wounds.

    PubMed

    Bao, Lei; Yang, Wei; Mao, Xuan; Mou, Shansong; Tang, Shunqing

    2008-12-01

    Agar, a highly hydrophilic polymer, has a special gel property and favorable biocompatibility, but moderate intension strength in an aqueous condition and a low degradation rate. In order to tailor both properties of mechanical intension and degradation, type I collagen was composited with agar in a certain ratio by drying at 50 degrees C or by a freeze-dry process. Glutaraldehyde was chosen as a crosslinking agent, and the most favorable condition for crosslinking was that the weight ratio of agar to glutaraldehyde was 66.7 and the pH value about 5. Dynamic mechanical analysis results showed that the single agar membrane had a modulus value between 640 MPa and 1064 MPa, but it was between 340 MPa and 819 MPa after being composited with type I collagen. It was discovered under an optical microscope that the pores were interconnected in the composite scaffolds instead of the honeycomb-like pores in a single type I collagen scaffold or the laminated gaps in a single agar scaffold. The results of an acute toxicity test disclosed that the composites were not toxic to mice although the composites were crosslinked with a certain concentration of glutaraldehyde. The results of gross examinations showed that when the composite membranes or scaffolds were applied to a repair rabbit skin lesion, the composites had a good repair effect without infection, liquid exudation or visible scar in the lesion covered with them. But in the control group, the autologous skin showed necrosis and there were a lot of scar tissues in the lesion site. H&E staining results showed that the repair tissue was similar to the normal one and very few scaffolds or membranes were left without degradation after 2 or 3 weeks. In conclusion, it is proved that type I collagen increases the toughness of the agar membrane, and the agar/type I collagen composites are promising biomaterials as wound dressings for healing burns or ulcers.

  6. Dressed skeleton expansion and the coupling scale ambiguity problem

    SciTech Connect

    Lu, Hung Jung

    1992-09-01

    Perturbative expansions in quantum field theories are usually expressed in powers of a coupling constant. In principle, the infinite sum of the expansion series is independent of the renormalization scale of the coupling constant. In practice, there is a remnant dependence of the truncated series on the renormalization scale. This scale ambiguity can severely restrict the predictive power of theoretical calculations. The dressed skeleton expansion is developed as a calculational method which avoids the coupling scale ambiguity problem. In this method, physical quantities are expressed as functional expansions in terms of a coupling vertex function. The arguments of the vertex function are given by the physical momenta of each process. These physical momenta effectively replace the unspecified renormalization scale and eliminate the ambiguity problem. This method is applied to various field theoretical models and its main features and limitations are explored. For quantum chromodynamics, an expression for the running coupling constant of the three-gluon vertex is obtained. The effective coupling scale of this vertex is shown to be essentially given by {mu}{sup 2} {approximately} Q{sub min}{sup 2}Q{sub med}{sup 2}/Q{sub max}{sup 2} where Q{sub min}{sup 2}Q{sub med}{sup 2}/Q{sub max}{sup 2} are respectively the smallest, the next-to-smallest and the largest scale among the three gluon virtualities. This functional form suggests that the three-gluon vertex becomes non-perturbative at asymmetric momentum configurations. Implications for four-jet physics is discussed.

  7. A comparison of the in vitro moisture vapour transmission rate and in vivo fluid-handling capacity of six adhesive foam dressings to a newly reformulated adhesive foam dressing.

    PubMed

    Zehrer, Cindy L; Holm, David; Solfest, Staci E; Walters, Shelley-Ann

    2014-12-01

    This study compared moisture vapour transmission rate (MVTR) and wear time or fluid-handling capacities of six adhesive foam dressings to a reformulated control dressing. Standardised in vitro MVTR methodology and a previously published in vivo artificial wound model (AWM) were used. Mean inverted MVTR for the reformulated dressing was 12 750 g/m(2) /24 hours and was significantly higher than four of the six comparator dressings (P < 0·0001), which ranged from 830 to 11 360 g/m(2) /24 hours. Mean upright MVTR for the reformulated dressing was 980 g/m(2) /24 hours and was significantly different than all of the comparator dressings (P < 0·0001), which ranged from 80 to 1620 g/m(2) /24 hours (three higher/three lower). The reformulated dressing median wear time ranged from 6·1 to >7·0 days, compared with 1·0 to 3·5 days for the comparator dressings (P = 0·0012 to P < 0·0001). The median fluid volume handled ranged from 78·0 to >87 ml compared with 13·0 to 44·5 ml for the comparator dressings (P = 0·0007 to P < 0·001). Interestingly, inverted MVTR did not correspond well to the AWM. These results suggest that marked differences exist between the dressings in terms of both MVTR and wear time or fluid-handling capacity. Furthermore, high inverted MVTR does not necessarily predict longer wear time or fluid-handling capacities of absorbent dressings.

  8. A comparison of the in vitro moisture vapour transmission rate and in vivo fluid-handling capacity of six adhesive foam dressings to a newly reformulated adhesive foam dressing.

    PubMed

    Zehrer, Cindy L; Holm, David; Solfest, Staci E; Walters, Shelley-Ann

    2014-12-01

    This study compared moisture vapour transmission rate (MVTR) and wear time or fluid-handling capacities of six adhesive foam dressings to a reformulated control dressing. Standardised in vitro MVTR methodology and a previously published in vivo artificial wound model (AWM) were used. Mean inverted MVTR for the reformulated dressing was 12 750 g/m(2) /24 hours and was significantly higher than four of the six comparator dressings (P < 0·0001), which ranged from 830 to 11 360 g/m(2) /24 hours. Mean upright MVTR for the reformulated dressing was 980 g/m(2) /24 hours and was significantly different than all of the comparator dressings (P < 0·0001), which ranged from 80 to 1620 g/m(2) /24 hours (three higher/three lower). The reformulated dressing median wear time ranged from 6·1 to >7·0 days, compared with 1·0 to 3·5 days for the comparator dressings (P = 0·0012 to P < 0·0001). The median fluid volume handled ranged from 78·0 to >87 ml compared with 13·0 to 44·5 ml for the comparator dressings (P = 0·0007 to P < 0·001). Interestingly, inverted MVTR did not correspond well to the AWM. These results suggest that marked differences exist between the dressings in terms of both MVTR and wear time or fluid-handling capacity. Furthermore, high inverted MVTR does not necessarily predict longer wear time or fluid-handling capacities of absorbent dressings. PMID:23362795

  9. A descriptive study of Korean nurses' perception of pain and skin tearing at dressing change.

    PubMed

    Kim, Jung Yoon; Kim, Na Kyung; Lee, Yun Jin

    2016-03-01

    This study aimed to investigate Korean nurses' level of awareness of pain and skin tearing in wound bed and/or peri-wound skin at dressing change. A descriptive study was performed. Convenience sampling was employed and registered nurses were recruited from attendees of continuing education program. A total of 399 participants (RN) completed questionnaire. Data was collected from September to November 2014. Many of them perceived skin tearing and wound related pain associated with dressing changing, but most of them did not assess and record pain and skin tearing at dressing change. More than half of respondents reported that they did not provide nursing intervention to prevent pain and skin tearing. Many of them reported that a systematic educational program for preventing pain and skin tearing at dressing change was needed. In conclusion, many of respondents were aware of pain and skin tearing at dressing change, but did not take any further necessary measures, including nursing intervention, for the most appropriate, systematic pain and skin tearing management. Therefore, this study suggested that a systematic and comprehensive educational program for Korean healthcare professions needs to be developed and implemented in Korea's hospital settings. PMID:26847938

  10. Surgical Adhesive Drape (IO-ban) as Postoperative Surgical Site Dressing

    PubMed Central

    Syed, Hasan R; Snyder, Rita; McGowan, Jason E; Jha, Ribhu T; Nair, Mani N

    2015-01-01

    Study Design: Retrospective chart analysis. Objective: The objective of this study is to describe the senior author’s (MNN) experience applying a widely available surgical drape as a postoperative sterile surgical site dressing for both cranial and spinal procedures. Summary of Background Data: Surgical site infection (SSI) is an important complication of spine surgery that can result in significant morbidity. There is wide variation in wound care management in practice, including dressing type. Given the known bactericidal properties of the surgical drape, there may be a benefit of continuing its use immediately postoperatively. Methods: All of the senior author’s cases from September 2014 through September 2015 were reviewed. These were contrasted to the previous year prior to the institution of a sterile surgical drape as a postoperative dressing. Results: Only one surgical case out of 157 operative interventions (35 cranial, 124 spinal) required operative debridement due to infection. From September 2013 to September 2014, prior to the institution of a sterile surgical drape as dressing, the author had five infections out of 143 operations (46 cranial, 97 spinal) requiring intervention. Conclusion: The implementation of a sterile surgical drape as a closed postoperative surgical site dressing has led to a decrease in surgical site infections. The technique is simple and widely available, and should be considered for use to diminish surgical site infections. PMID:26798570

  11. Aquacel Surgical Dressing after Thigh Lift: A Case–Control Study

    PubMed Central

    Bocchiotti, Maria A.; Baglioni, Elisabetta A.; Spaziante, Luca; Frenello, Ambra

    2016-01-01

    Background: The postoperative dressing in patients undergoing thigh lift is often difficult, not very resistant to movement, and uncomfortable for the patient, and often exposes surgical site to infection, maceration, or delay in wound healing. Methods: We included 40 patients in a case–control crossover study with no period effects, who were treated both by Aquacel Surgical and a traditional wound dressing. Surveys with a 10-point scale evaluation were used to assess nontraumatic removal level, ease of application, adhesion, and strength of the 2 treatments. We reported the number of days necessary for wound healing, the number of infection cases, and wound-related complications. Costs of the 2 medications were also considered. Ten days after surgery, patients answered a questionnaire with 6 multiple-choice questions to assess comfort, pain at dressing change, pruritus, strength, and number of dressing changes. Results: Compared with controls, surveys revealed Aquacel Surgical to be less traumatic to remove, easier to apply, and to be more adherent and stronger. Significant acceleration of the wound healing was also evident with Aquacel Surgical compared with the traditional dressing. Nonsignificant differences were reported about the risk of infection and wound-related complications between the 2 treatments. A statistical analysis of costs revealed that Aquacel Surgical is significantly more expensive than the traditional medication. Conclusion: We recommend the use of Aquacel Surgical in all the surgery procedures where the risk of wound dehiscence and maceration is high. PMID:27757328

  12. Contaminated first-aid dressings: report of a working party of the PHLS.

    PubMed Central

    Marples, R. R.

    1983-01-01

    In a collaborative study 12 Public Health Laboratory Service laboratories and the Division of Hospital Infection, Central Public Health Laboratory, investigated the degree of contamination of standard dressings produced by manufacturers in India or in England by a comparison of the results of culture of 25 sterilized dressings with those of 25 untreated dressings. Of the 38 batches of dressings made in India 27 (71%) were judged contaminant and another six could be so judged when Bacillus species were examined. In two batches laboratory contamination precluded a judgement and only three batches passed the test. Of the 27 batches made in England, only three gave any evidence of contamination at the lowest level of significance. Repeat investigation of one of these batches gave no evidence of contamination. Organisms of the genus Bacillus and fungi were associated with contamination; micrococci and propionibacteria were laboratory contaminants. There was evidence for both failure and sterilization and of contamination after sterilization during the manufacture of dressings. PMID:6339612

  13. [Original vacuum dressing for the treatment of open femur fracture with gangrene immobilized by external fixation].

    PubMed

    Debarge, R; Pinaroli, A; Caillot, J-L; Voiglio, E-J

    2008-02-01

    We report a case of gangrene, which developed following an open fracture of the femur immobilized with an external fixator in a 45-year-old patient. A conventional vacuum dressing (VAC Therapy) could not be applied with the external fixator in place. An original vacuum dressing was thus fashioned after surgical debridement. Scabs were covered with calcium alginate. The lower limb was enveloped in sterile dressings and vacuum was achieved by suction with gastric tubes under adhesive films. The dressing was redone every 48 h in a surgical setting. Antibiotic prophylaxis enabled cure of the infection. Budding appeared within two weeks enabling skin grafting. Centro-medullary nailing was undertaken on day 30 to accelerate bone healing. At three months from the trauma, the initial loss of sensitivity in the leg and foot noted at the first weight bearing required programmed disarticulation of the knee after femur and wound healing. At six months, the patient had resumed his occupational activities and was pain free. This type of dressing could be useful for tissue loss over a fracture immobilized with an external fixator. This type of assembly can easily be installed in the operating room. PMID:18342034

  14. A toroidal trap for cold {}^{87}{Rb} atoms using an rf-dressed quadrupole trap

    NASA Astrophysics Data System (ADS)

    Chakraborty, A.; Mishra, S. R.; Ram, S. P.; Tiwari, S. K.; Rawat, H. S.

    2016-04-01

    We demonstrate the trapping of cold {}87{Rb} atoms in a toroidal geometry using a radio frequency (rf) dressed quadrupole magnetic trap formed by superposing a strong rf-field on a quadrupole trap. This rf-dressed quadrupole trap has the minimum potential away from the quadrupole trap centre on a circular path which facilitates trapping in toroidal geometry. In these experiments, the laser cooled atoms were first trapped in a quadrupole trap, then cooled evaporatively using a weak rf-field, and finally trapped in an rf-dressed quadrupole trap. The radius of the toroid could be varied by varying the frequency of the dressing rf-field. It has also been demonstrated that a single rf source and an antenna can be used for the rf-evaporative cooling as well as for the rf-dressing of atoms. The atoms trapped in the toroidal trap may have applications in the realization of an atom gyroscope as well as in studying the quantum gases in low dimensions.

  15. Preparation of SMART wound dressings based on colloidal microgels and textile fibres

    NASA Astrophysics Data System (ADS)

    Cornelius, Victoria J.; Majcen, Natasa; Snowden, Martin J.; Mitchell, John C.; Voncina, Bojana

    2007-01-01

    Wound dressings and other types of wound healing technologies are experiencing fast-paced development and rapid growth. As the population ages, demand will continue to rise for advanced dressings used to treat chronic wounds, such as pressure ulcers, venous stasis ulcers, and diabetic ulcers. Moist wound dressings, which facilitate natural wound healing in a cost-effective manner, will be increasingly important. In commercially available hydrogel / gauze wound dressings the gel swells to adsorb wound excreta and provide an efficient non adhesive particle barrier. An alternative to hydrogels are microgels. Essentially discrete colloidal gel particles, as a result of their very high surface area to volume ratio compared to bulk gels, they have a much faster response to external stimuli such as temperature or pH. In response to either an increase or decrease in solvent quality these porous networks shrink and swell reversibly. When swollen the interstitial regions within the polymer matrix are available for further chemistry; such as the incorporation of small molecules. The reversible shrinking and swelling as a function of external stimuli provides a novel drug release system. As the environmental conditions of a wound change over its lifetime, tending to increase in pH if there is an infection combining these discrete polymeric particles with a substrate such as cotton, results in a smart wound dressing.

  16. Clinical Efficacy Test of Polyester Containing Herbal Extract Dressings in Burn Wound Healing.

    PubMed

    Muangman, Pornprom; Praditsuktavorn, Banjerd; Chinaroonchai, Kusuma; Chuntrasakul, Chomchark

    2016-09-01

    Technological advancement has assisted in developing various availabilities of wound products that help in not only in healing and preventing infection but also in providing patients' comfort and pain reduction during application. However, most of advanced wound healing products in Thailand were imported at high costs to patients. Nowadays, there are increased numbers of local researches of herbs that could provide healing environment for successful wound care. Herbal wound products are currently being introduced as alternatives to those imported dressings. The aim of this study was to report the clinical efficacy of using polyester containing herbal extract dressings in healing of second-degree burns. The volunteers were divided by simply randomized method into the study group of patient using polyester containing herbal extract dressing and the control group of patients treating with dressings that are commercially available and common use. The standard treatment protocols were performed at every 3 days of dressing change. Comparative evaluation consisted of time of healing, length of hospital stays, pain analog score assessment, percentage of infection, and descriptive notification of unfavorable clinical symptoms or signs or side effects.

  17. An in vitro test of the efficacy of an anti-biofilm wound dressing.

    PubMed

    Said, Jawal; Walker, Michael; Parsons, David; Stapleton, Paul; Beezer, Anthony E; Gaisford, Simon

    2014-10-20

    Broad-spectrum antimicrobial agents, such as silver, are increasingly being formulated into medicated wound dressings in order to control colonization of wounds by opportunistic pathogens. Medicated wound dressings have been shown in-vitro to be effective against planktonic cultures, but in-vivo bacteria are likely to be present in biofilms, which makes their control and eradication more challenging. Recently, a functional wound dressing (AQUACEL(®) Ag+ Extra™ (AAg + E)) has been developed that in addition to silver contains two agents (ethylenediaminetetraacetic acid (EDTA) and benzethonium chloride (BC)) designed to disrupt biofilms. Here, the efficacy of AAg + E is demonstrated using a biofilm model developed in an isothermal microcalorimeter. The biofilm was seen to remain viable in the presence of unmedicated dressing, silver-containing dressing or silver nitrate solution. In the presence of AAg + E, however, the biofilm was eradicated. Control experiments showed that neither EDTA nor BC alone had a bactericidal effect, which means it is the synergistic action of EDTA and BC disrupting the biofilm with silver being bactericidal that leads to the product's efficacy.

  18. Electrospun nanofibers as dressings for chronic wound care: advances, challenges, and future prospects.

    PubMed

    Abrigo, Martina; McArthur, Sally L; Kingshott, Peter

    2014-06-01

    Chronic non-healing wounds show delayed and incomplete healing processes and in turn expose patients to a high risk of infection. Treatment currently focuses on dressings that prevent microbial infiltration and keep a balanced moisture and gas exchange environment. Antibacterial delivery from dressings has existed for some time, with responsive systems now aiming to trigger release only if infection occurs. Simultaneously, approaches that stimulate cell proliferation in the wound and encourage healing have been developed. Interestingly, few dressings appear capable of simultaneously impairing or treating infection and encouraging cell proliferation/wound healing. Electrospinning is a simple, cost-effective, and reproducible process that can utilize both synthetic and natural polymers to address these specific wound challenges. Electrospun meshes provide high-surface area, micro-porosity, and the ability to load drugs or other biomolecules into the fibers. Electrospun materials have been used as scaffolds for tissue engineering for a number of years, but there is surprisingly little literature on the interactions of fibers with bacteria and co-cultures of cells and bacteria. This Review examines the literature and data available on electrospun wound dressings and the research that is required to develop smart multifunctional wound dressings capable of treating infection and healing chronic wounds.

  19. Clinical Efficacy Test of Polyester Containing Herbal Extract Dressings in Burn Wound Healing.

    PubMed

    Muangman, Pornprom; Praditsuktavorn, Banjerd; Chinaroonchai, Kusuma; Chuntrasakul, Chomchark

    2016-09-01

    Technological advancement has assisted in developing various availabilities of wound products that help in not only in healing and preventing infection but also in providing patients' comfort and pain reduction during application. However, most of advanced wound healing products in Thailand were imported at high costs to patients. Nowadays, there are increased numbers of local researches of herbs that could provide healing environment for successful wound care. Herbal wound products are currently being introduced as alternatives to those imported dressings. The aim of this study was to report the clinical efficacy of using polyester containing herbal extract dressings in healing of second-degree burns. The volunteers were divided by simply randomized method into the study group of patient using polyester containing herbal extract dressing and the control group of patients treating with dressings that are commercially available and common use. The standard treatment protocols were performed at every 3 days of dressing change. Comparative evaluation consisted of time of healing, length of hospital stays, pain analog score assessment, percentage of infection, and descriptive notification of unfavorable clinical symptoms or signs or side effects. PMID:27440796

  20. Chronic Hepatitis C Therapy in Liver Cirrhosis Complicated by Telaprevir-Induced DRESS

    PubMed Central

    Mousa, Omar Y. S.; Khalaf, Rossa; Shannon, Rhonda L.; Egwim, Chukwuma I.; Zela, Scott A.; Ankoma-Sey, Victor

    2014-01-01

    Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare yet severe adverse drug-induced reaction with up to 10% mortality rate. Recent clinical trials reported an association between DRESS and telaprevir (TVR), an NS3/4A protease inhibitor of chronic hepatitis C (CHC) virus genotype 1. Its diagnosis is challenging given the variable pattern of cutaneous eruption and the myriad internal organ involvement. We present two patients who are middle-aged, obese, and white with CHC cirrhosis. They both developed a progressive diffuse, painful pruritic maculopapular rash at weeks 8 and 10 of CHC therapy with TVR, Peg-Interferon alfa-2a, and Ribavirin. They had no exposures to other medications that can cause this syndrome. Physical exam and labs and skin biopsy supported a “Definite” clinical diagnosis of DRESS, per RegiSCAR criteria. Thus Telaprevir-based triple therapy was discontinued and both patients experienced rapid resolution of the systemic symptoms with gradual improvement of eosinophilia and the skin eruption. These two cases illustrate the paramount importance of having a high index of suspicion for TVR-induced DRESS, critical for early diagnosis. Immediate discontinuation of TVR is essential in prevention of a potentially life-threatening complication. Risk factors for development of DRESS in patients receiving TVR remain to be elucidated. PMID:25214847

  1. Thrombin Production and Human Neutrophil Elastase Sequestration by Modified Cellulosic Dressings and Their Electrokinetic Analysis

    PubMed Central

    Edwards, Judson Vincent; Prevost, Nicolette

    2011-01-01

    Wound healing is a complex series of biochemical and cellular events. Optimally, functional material design addresses the overlapping acute and inflammatory stages of wound healing based on molecular, cellular, and bio-compatibility issues. In this paper the issues addressed are uncontrolled hemostasis and inflammation which can interfere with the orderly flow of wound healing. In this regard, we review the serine proteases thrombin and elastase relative to dressing functionality that improves wound healing and examine the effects of charge in cotton/cellulosic dressing design on thrombin production and elastase sequestration (uptake by the wound dressing). Thrombin is central to the initiation and propagation of coagulation, and elastase is released from neutrophils that can function detrimentally in a stalled inflammatory phase characteristic of chronic wounds. Electrokinetic fiber surface properties of the biomaterials of this study were determined to correlate material charge and polarity with function relative to thrombin production and elastase sequestration. Human neutrophil elastase sequestration was assessed with an assay representative of chronic wound concentration with cotton gauze cross-linked with three types of polycarboxylic acids and one phosphorylation finish; thrombin production, which was assessed in a plasma-based assay via a fluorogenic peptide substrate, was determined for cotton, cotton-grafted chitosan, chitosan, rayon/polyester, and two kaolin-treated materials including a commercial hemorrhage control dressing (QuickClot Combat Gauze). A correlation in thrombin production to zeta potential was found. Two polycarboxylic acid cross linked and a phosphorylated cotton dressing gave high elastase sequestration. PMID:24956451

  2. Thrombin production and human neutrophil elastase sequestration by modified cellulosic dressings and their electrokinetic analysis.

    PubMed

    Edwards, Judson Vincent; Prevost, Nicolette

    2011-12-15

    Wound healing is a complex series of biochemical and cellular events. Optimally, functional material design addresses the overlapping acute and inflammatory stages of wound healing based on molecular, cellular, and bio-compatibility issues. In this paper the issues addressed are uncontrolled hemostasis and inflammation which can interfere with the orderly flow of wound healing. In this regard, we review the serine proteases thrombin and elastase relative to dressing functionality that improves wound healing and examine the effects of charge in cotton/cellulosic dressing design on thrombin production and elastase sequestration (uptake by the wound dressing). Thrombin is central to the initiation and propagation of coagulation, and elastase is released from neutrophils that can function detrimentally in a stalled inflammatory phase characteristic of chronic wounds. Electrokinetic fiber surface properties of the biomaterials of this study were determined to correlate material charge and polarity with function relative to thrombin production and elastase sequestration. Human neutrophil elastase sequestration was assessed with an assay representative of chronic wound concentration with cotton gauze cross-linked with three types of polycarboxylic acids and one phosphorylation finish; thrombin production, which was assessed in a plasma-based assay via a fluorogenic peptide substrate, was determined for cotton, cotton-grafted chitosan, chitosan, rayon/polyester, and two kaolin-treated materials including a commercial hemorrhage control dressing (QuickClot Combat Gauze). A correlation in thrombin production to zeta potential was found. Two polycarboxylic acid cross linked and a phosphorylated cotton dressing gave high elastase sequestration.

  3. Amniotic membrane extract-loaded double-layered wound dressing: evaluation of gel properties and wound healing.

    PubMed

    Choi, Yeung Keun; Din, Fakhar Ud; Kim, Dong Wuk; Kim, Yong-Il; Kim, Jong Oh; Ku, Sae Kwang; Ra, Jeong-Chan; Huh, Jae-Wook; Lee, Jangik I; Sohn, Dong Hwan; Yong, Chul Soon; Choi, Han-Gon

    2014-07-01

    The conservative single-layered wound dressing system is decomposed when mixed in polyvinyl alcohol (PVA) solution, which means it cannot be used with a temperature-sensitive drug. The goal of this investigation was to make an amniotic membrane extract (AME)-loaded double-layered wound dressing with an improved healing result compared to the conservative single-layered wound dressing systems. The double-layered wound dressing was developed with PVA/sodium alginate using a freeze-melting technique; one layer was PVA layer and the other was the drug-loaded sodium alginate layer. Its gel properties were assessed compared to single-layered wound dressings. Moreover, in vivo wound-healing effects and histopathology were calculated compared to commercial products. The double-layered wound dressing gave a similar gel fraction and Young's module as single-layered wound bandages developed with only PVA, and a similar inflammation ability and WVTR as single-layered wound dressings developed with PVA and sodium alginate. Our data indicate that these double-layered wound bandages were just as swellable, but more elastic and stronger than single-layered wound dressings comprised of the same polymers and quantities, possibly giving an acceptable level of moisture and accumulation of exudates in the wound zone. Compared to the commercial product, the double-layered wound dressing comprising 6.7% PVA, 0.5% sodium alginate and 0.01% AME significantly enhanced the wound-healing effect in the wound-healing test. Histological investigations showed that superior full-thickness wound-healing effects compared to the commercial product. Therefore, the double-layered wound dressing would be an outstanding wound-dressing system with improved wound healing and good gel property.

  4. Development of a functional wound dressing composed of hyaluronic acid spongy sheet containing bioactive components: evaluation of wound healing potential in animal tests.

    PubMed

    Shimizu, Nahoko; Ishida, Daiki; Yamamoto, Akiko; Kuroyanagi, Misato; Kuroyanagi, Yoshimitsu

    2014-01-01

    This study aimed to develop a novel wound dressing composed of hyaluronic acid (HA) spongy sheet containing bioactive components. The wound dressing prepared by the freeze-drying method has a two-layered structure: an upper layer composed of cross-linked high-molecular-weight HA (HMW-HA) and a lower layer composed of low-molecular-weight HA (LMW-HA) containing arginine (Arg), magnesium ascorbyl phosphate (vitamin C derivative: VC), and epidermal growth factor (EGF) (referred to as EGF-dressing). A wound dressing containing only Arg and VC was prepared in a similar manner (referred to as EGF-free-dressing). The potential of each wound dressing was evaluated in animal tests using Sprague Dawley (SD) rats and diabetic mice. In the first experiment, each wound dressing was applied to a full-thickness skin defect in the abdominal region of SD rats. Wound conditions after 1 week and 2 weeks of treatment were evaluated based on macroscopic and histological appearance. A commercially available non-woven alginate wound dressing (Alg-dressing) was used in a control group. Both EGF-free-dressing and EGF-dressing decreased wound size and promoted granulation tissue formation associated with angiogenesis more effectively when compared with Alg-dressing. In particular, EGF-dressing promoted re-epithelialization. In the second experiment, each wound dressing was applied to a full-thickness skin defect in the dorsal region of diabetic mice. Wound conditions after 1 week and 2 weeks of treatment were evaluated based on macroscopic and histological appearance. A commercially available Alg-dressing was used in a control group. Both EGF-free-dressing and EGF-dressing decreased wound size and promoted granulation tissue formation associated with angiogenesis more effectively when compared with Alg-dressing. These findings indicate that EGF-free-dressing and EGF-dressing have the potential for more effective wound healing when compared with Alg-dressing. In particular, EGF-dressing has

  5. Development of a functional wound dressing composed of hyaluronic acid spongy sheet containing bioactive components: evaluation of wound healing potential in animal tests.

    PubMed

    Shimizu, Nahoko; Ishida, Daiki; Yamamoto, Akiko; Kuroyanagi, Misato; Kuroyanagi, Yoshimitsu

    2014-01-01

    This study aimed to develop a novel wound dressing composed of hyaluronic acid (HA) spongy sheet containing bioactive components. The wound dressing prepared by the freeze-drying method has a two-layered structure: an upper layer composed of cross-linked high-molecular-weight HA (HMW-HA) and a lower layer composed of low-molecular-weight HA (LMW-HA) containing arginine (Arg), magnesium ascorbyl phosphate (vitamin C derivative: VC), and epidermal growth factor (EGF) (referred to as EGF-dressing). A wound dressing containing only Arg and VC was prepared in a similar manner (referred to as EGF-free-dressing). The potential of each wound dressing was evaluated in animal tests using Sprague Dawley (SD) rats and diabetic mice. In the first experiment, each wound dressing was applied to a full-thickness skin defect in the abdominal region of SD rats. Wound conditions after 1 week and 2 weeks of treatment were evaluated based on macroscopic and histological appearance. A commercially available non-woven alginate wound dressing (Alg-dressing) was used in a control group. Both EGF-free-dressing and EGF-dressing decreased wound size and promoted granulation tissue formation associated with angiogenesis more effectively when compared with Alg-dressing. In particular, EGF-dressing promoted re-epithelialization. In the second experiment, each wound dressing was applied to a full-thickness skin defect in the dorsal region of diabetic mice. Wound conditions after 1 week and 2 weeks of treatment were evaluated based on macroscopic and histological appearance. A commercially available Alg-dressing was used in a control group. Both EGF-free-dressing and EGF-dressing decreased wound size and promoted granulation tissue formation associated with angiogenesis more effectively when compared with Alg-dressing. These findings indicate that EGF-free-dressing and EGF-dressing have the potential for more effective wound healing when compared with Alg-dressing. In particular, EGF-dressing has

  6. Pressure Ulcer Prevention in the Hospital Setting Using Silicone Foam Dressings.

    PubMed

    Truong, Bao; Grigson, Eileen; Patel, Maulik; Liu, Xinwei

    2016-01-01

    Patient care is of the utmost importance in the hospital setting. Bedrest and immobility during hospitalization, especially in the surgical and intensive care setting, place the patient at high risk for pressure ulcers. It is very important to prevent or notice a pressure ulcer forming due to the significant health care costs involved and patient health associated with them. Various measures are in place to prevent patients from getting pressure ulcers, but a newer material, silicone foam dressings, has been introduced as an alternative solution for the prevention of these ulcers. We review the current literature to examine whether the standard protocol or silicone material is superior to the prevention of pressure ulcer formation. We conclude that silicone foam dressings, when used as prophylactic treatment, seems very promising and may even be superior to the standard care of prevention. However, there were limitations to some studies and further research is needed to confirm the role of silicone foam dressings. PMID:27630803

  7. Topical Agents and Dressings for Pilonidal Sinus Wound Healing by Secondary Intention: A Scoping Review.

    PubMed

    Woo, Kevin Y; Kwong, Enid Wai-Yung; Jimenez, Carolina; Bishop, Richard

    2015-05-01

    Pilonidal disease (PD) is a chronic and debilitating condition. The overall aim of the scoping review is to map and summarize a wide range of evidence to examine which topical agent or dressing is effective in promoting pilonidal wound healing by secondary intention. Review of this cumulative body of evidence will inform care and guide dressing selection for PD related wounds and delineate future research priorities based on identified knowledge gaps and clinical practice issues. Overall, there is some evidence to suggest that topical applications of hydrogel, silver, honey, zinc, selected foam materials, negative pressure wound therapy, platelet rich plasma, and plant extracts may promote wound healing. Topical treatment using polyhexamethylene biguanide and silver may be beneficial in reducing bacterial burden. Finally, silver, honey, and hydrocolloid dressings may help alleviate wound related pain. However, evidence remains insufficient in light of methodological limitations and biases of the studies.

  8. Spin-orbit coupled Bose-Einstein condensates with Rydberg-dressing interaction

    NASA Astrophysics Data System (ADS)

    Lü, Hao; Zhu, Shao-Bing; Qian, Jun; Wang, Yu-Zhu

    2015-09-01

    Interaction between Rydberg atoms can be used to control the properties of interatomic interaction in ultracold gases by weakly dressing the atoms with a Rydberg state. Here we investigate the effect of the Rydberg-dressing interaction on the ground-state properties of a Bose-Einstein condensate imposed by Raman-induced spin-orbit coupling. We find that, in the case of SU(2)-invariant s-wave interactions, the gas is only in the plane-wave phase and the zero-momentum phase is absent. In particular, we also predict an unexpected magnetic stripe phase composed of two plane-wave components with unequal weight when s-wave interactions are non-symmetric, which originates from the Rydberg-dressing interaction. Project supported by the National Basic Research Program of China (Grant No. 2011CB921504) and the National Natural Science Foundation of China (Grant No. 11104292).

  9. HydroColloid dressing (Duoderm) for the treatment of superficial and deep partial thickness burns.

    PubMed

    Hermans, M H

    1987-01-01

    HydroColloid Dressing (Duoderm, HCD) is a new kind of dressing, based on the fact that occlusion can provide an optimum wound environment for quick re-epithelialization. Seventy patients with superficial and deep partial thickness burns of up to 7% TBSA were treated with HCD. In 16 patients a second burned area, similar in size and depth of the burn treated with HCD, was treated with human allografts or silversulfadiazine (SSD). Five patients with very small full thickness burns were also treated with HCD. In three patients (4.5%) the treatment with HCD had to be discontinued before total re-epithelialization had occurred, for various reasons. Statistically, HCD provided faster re-epithelialization than allografts or SSD. The cosmetic and functional results were excellent. After six months only one patient was found to have a small area of hypertrophy. In this study HCD was found to be a very good dressing for the treatment of smaller partial thickness burns.

  10. The football: an intuitive dressing for offloading neuropathic plantar forefoot ulcerations.

    PubMed

    Rader, Andrew J; Barry, Timothy P

    2008-03-01

    A reproducible, affordable, efficacious and safe modality for offloading neuropathic plantar foot ulcerations was previously presented in a pilot study. A follow-up retrospective multicentre analysis of the football dressing is now presented. Wound healing rates are compared with published data on the total contact cast (TCC) and instant total contact cast (iTCC). Overall wound healing rates for University of Texas Health Science Center class 1A, 1B, 1C, 1D, 2A, 2B, 2C and 3B plantar forefoot ulcerations is 2.91 weeks with a 95% confidence interval of 2.36-3.47 weeks for complete wound epithelialisation. The cost associated with this dressing technique is a fraction of that associated with the TCC and iTCC. The ease of application coupled with reliable healing rates and affordable materials makes the football dressing a worthy partner against the sequelae of plantar forefoot ulcerations.

  11. Pressure Ulcer Prevention in the Hospital Setting Using Silicone Foam Dressings

    PubMed Central

    Grigson, Eileen; Patel, Maulik; Liu, Xinwei

    2016-01-01

    Patient care is of the utmost importance in the hospital setting. Bedrest and immobility during hospitalization, especially in the surgical and intensive care setting, place the patient at high risk for pressure ulcers. It is very important to prevent or notice a pressure ulcer forming due to the significant health care costs involved and patient health associated with them. Various measures are in place to prevent patients from getting pressure ulcers, but a newer material, silicone foam dressings, has been introduced as an alternative solution for the prevention of these ulcers. We review the current literature to examine whether the standard protocol or silicone material is superior to the prevention of pressure ulcer formation. We conclude that silicone foam dressings, when used as prophylactic treatment, seems very promising and may even be superior to the standard care of prevention. However, there were limitations to some studies and further research is needed to confirm the role of silicone foam dressings.

  12. Magic radio-frequency dressing of nuclear spins in high-accuracy optical clocks.

    PubMed

    Zanon-Willette, Thomas; de Clercq, Emeric; Arimondo, Ennio

    2012-11-30

    A Zeeman-insensitive optical clock atomic transition is engineered when nuclear spins are dressed by a nonresonant radio-frequency field. For fermionic species as (87)Sr, (171)Yb, and (199)Hg, particular ratios between the radio-frequency driving amplitude and frequency lead to "magic" magnetic values where a net cancelation of the Zeeman clock shift and a complete reduction of first-order magnetic variations are produced within a relative uncertainty below the 10(-18) level. An Autler-Townes continued fraction describing a semiclassical radio-frequency dressed spin is numerically computed and compared to an analytical quantum description including higher-order magnetic field corrections to the dressed energies.

  13. [Study of transport properties of the polymeric membranous dressing with silver ions].

    PubMed

    Slezak, Andrzej; Kucharzewski, Marek; Grzegorczyn, Sławomir; Slezak, Izabella H

    2005-01-01

    The transport properties of polymeric membraneous dresing silver ion containing Textus Bioactive were studied. This dressing is made of three types of theromoplastic polymeric fibers, formed into two-layers membrane. In first layer occure the polymeric fiber, which the core is hydrophobic and hydrophilic surfaces contain a silver zeolite. These fibers neighborours with hydrophilic super absorbing polymers. Third type of polymeric fibers occur in the second layer of membrane and is arranged parallel to surface's skin, creating a net preventing stick of membraneous dressing to treated wound. Using of the Kedem-Katchalsky equations the transport model of this membrane and the temporal and concentration characteristics of transport parameters (hydraulic permeability, refection and solute permeability) were determined. Experimental results show that the polymeric membranous dressing contain the silver ions posses non-linear transport properties, which are consequence of structure and physicochemical properties of polymeric membranes.

  14. Topical Agents and Dressings for Pilonidal Sinus Wound Healing by Secondary Intention: A Scoping Review.

    PubMed

    Woo, Kevin Y; Kwong, Enid Wai-Yung; Jimenez, Carolina; Bishop, Richard

    2015-05-01

    Pilonidal disease (PD) is a chronic and debilitating condition. The overall aim of the scoping review is to map and summarize a wide range of evidence to examine which topical agent or dressing is effective in promoting pilonidal wound healing by secondary intention. Review of this cumulative body of evidence will inform care and guide dressing selection for PD related wounds and delineate future research priorities based on identified knowledge gaps and clinical practice issues. Overall, there is some evidence to suggest that topical applications of hydrogel, silver, honey, zinc, selected foam materials, negative pressure wound therapy, platelet rich plasma, and plant extracts may promote wound healing. Topical treatment using polyhexamethylene biguanide and silver may be beneficial in reducing bacterial burden. Finally, silver, honey, and hydrocolloid dressings may help alleviate wound related pain. However, evidence remains insufficient in light of methodological limitations and biases of the studies. PMID:26054992

  15. Electrospun polyurethane-dextran nanofiber mats loaded with Estradiol for post-menopausal wound dressing.

    PubMed

    Unnithan, Afeesh Rajan; Sasikala, Arathyram Ramachandra Kurup; Murugesan, Priya; Gurusamy, Malarvizhi; Wu, Dongmei; Park, Chan Hee; Kim, Cheol Sang

    2015-01-01

    Post-menopausal wound care management is a substantial burden on health services, since there are an increased number of elderly populations linked with age-related delayed wound healing. The controlled estrogen replacement can accelerate healing of acute cutaneous wounds, linked to its potent anti-inflammatory activity. The electrospinning technique can be used to introduce the desired therapeutic agents to the nanofiber matrix. So here we introduce a new material for wound tissue dressing, in which a polyurethane-dextran composite nanofibrous wound dressing material loaded with β-estradiol was obtained through electrospinning. Dextran can promote neovascularization and skin regeneration in chronic wounds. This study involves the characterization of these nanofibers and analysis of cell growth and proliferation to determine the efficiency of tissue regeneration on these biocomposite polymer nanofibrous scaffolds and to study the possibility of using it as a potential wound dressing material in the in vivo models. PMID:25748849

  16. Honey-based dressings and wound care: an option for care in the United States.

    PubMed

    Pieper, Barbara

    2009-01-01

    Honey-based wound dressings have been used worldwide since ancient times. A honey product received US Federal Drug Administration approval in 2007, making this dressing an option for wound care. Honey has been found to exert anti-inflammatory and antibacterial effects without antibiotic resistance, promote moist wound healing, and facilitate debridement. However, it may cause a stinging pain. As is true of any wound dressing, its use must be carefully selected and monitored. Continued research is needed to add to its evidence base. This article provides a summary of the current evidence base for the use of honey and a review of its therapeutic effects and discusses implications for WOC nursing practice.

  17. Hyaluronic acid and silver sulfadiazine-impregnated polyurethane foams for wound dressing application.

    PubMed

    Cho, Y-S; Lee, J-W; Lee, J-S; Lee, J H; Yoon, T R; Kuroyanagi, Y; Park, M H; Pyun, D G; Kim, H J

    2002-09-01

    Five different kinds of PU foam wound dressings were prepared to investigate their wound healing capability. They include (i) PU+silver sulfadiazine (AgSD), (ii) PU+alginate (Al), (iii) PU+Al+AgSD, (i.v.) PU+hyaluronic acid (HA), and (v) PU+HA+AgSD. Physical properties and in vitro behaviors of AgSD release and fibroblast adhesion on those dressings were evaluated. From the drug release and fibroblast adhesion studies, it was observed that PU foam impregnated with both HA and AgSD shows good drug release behavior and low adhesion of the cells. Furthermore, the HA and AgSD-containing PU foam showed excellent wound healing effect without any inflammation or yellow cluster. The wound size decreased around 77% after 1 week application of that foam dressing onto a rat skin defect.

  18. Magic radio-frequency dressing of nuclear spins in high-accuracy optical clocks.

    PubMed

    Zanon-Willette, Thomas; de Clercq, Emeric; Arimondo, Ennio

    2012-11-30

    A Zeeman-insensitive optical clock atomic transition is engineered when nuclear spins are dressed by a nonresonant radio-frequency field. For fermionic species as (87)Sr, (171)Yb, and (199)Hg, particular ratios between the radio-frequency driving amplitude and frequency lead to "magic" magnetic values where a net cancelation of the Zeeman clock shift and a complete reduction of first-order magnetic variations are produced within a relative uncertainty below the 10(-18) level. An Autler-Townes continued fraction describing a semiclassical radio-frequency dressed spin is numerically computed and compared to an analytical quantum description including higher-order magnetic field corrections to the dressed energies. PMID:23368116

  19. Coherent transient in dressed-state and transient spectra of Autler-Townes doublet

    SciTech Connect

    Zhang Lianshui; Feng Xiaomin; Fu Guangsheng; Li Xiaowei; Han Li; Manson, Neil B.; Wei Changjiang

    2004-12-01

    In this paper we present a theoretical study of the time-dependent probe response in the presence of a strong pump field in a three-level pump-probe configuration. Two situations are investigated: a cw pump with a pulsed probe field and a pulsed pump with a cw probe field. The results are explained as dressed-state nutation and nutation by dynamic Stark switching. Dressed-state quantum beats are also an important feature for both situations. Furthermore, when a 90 deg. phase shift after a {pi}/2 period is introduced in the pulsed probe field, there is a spin locking in the dressed-state transition. Our results give a satisfactory theoretical account of a previous experimental observation [Wei et al., Phys. Rev. Lett. 74, 1083 (1995)].

  20. Development and physicochemical characterization of alginate composite film loaded with simvastatin as a potential wound dressing.

    PubMed

    Rezvanian, Masoud; Amin, Mohd Cairul Iqbal Mohd; Ng, Shiow-Fern

    2016-02-10

    Previously, studies have demonstrated that topical application of simvastatin can promote wound healing in diabetic mice via augmentation of angiogenesis and lymphangiogenesis. This study aimed to formulate and characterize simvastatin in alginate-based composite film wound dressings. Biopolymers used for composite films were sodium alginate blended with pectin or gelatin. The films were prepared and characterized based on their physical properties, surface morphology, mechanical strength and rheology. Then, in vitro drug releases from the films were investigated and, finally, the cell viability assay was performed to assess the cytotoxicity profile. From the pre-formulation studies, alginate/pectin composite film showed to possess desirable wound dressing properties and superior mechanical properties. The in vitro drug release profile revealed that alginate/pectin film produced a controlled release drug profile, and cell viability assay showed that the film was non-toxic. In summary, alginate/pectin composite film is suitable to be formulated with simvastatin as a potential wound dressing.

  1. The purple coloration of four late 19th century silk dresses: A spectroscopic investigation

    NASA Astrophysics Data System (ADS)

    Woodhead, Andrea L.; Cosgrove, Bronwyn; Church, Jeffrey S.

    2016-02-01

    Prior to the 19th century the use of purple dyes for textile coloration was expensive and usually limited to royalty. The discovery of several synthetic purple dyes during the 19th century made the production of purple textiles more affordable and thus more readily available. The identification of the source of the purple coloration is of historical interest. Small yarn samples from four late 19th century silk dresses were analyzed using a combination of thin layer chromatography and surface enhanced Raman spectroscopy, Fourier transform infrared spectroscopy and energy dispersive x-ray spectroscopy. This combination of techniques enabled the analysis of the complex extraction products. While three of the dresses were found to be dyed using methyl violet, the fourth dress was found to be constructed from a warp yarn dyed with methyl violet in the presence of a tannic acid mordant, and a weft yarn dyed with mauve and a tin mordant.

  2. Studies on the disposable obstetrical dressings sterilized by radiation and the effect of its application

    NASA Astrophysics Data System (ADS)

    Haiqiao, Wang; Sujing, Sun

    1993-10-01

    In order to attain an optimum sterilization treatment to obstetric dressings, a new product made by us, with 60Coγ-ray, the effects of radiation on standard bacteria pseudomonas aeruginosa ATcc27853, Escherichia coli ATcc25922, Staphylococcus aureus ATcc25923, Clostridium PB6KA, short Bacillus E60163202 and HBSAg were studied. Results showed that at the absorbed dose of 10 kGy, all the bacteria, bacillus and HBSAg were killed off, and sterilized with the dose, the dressings can completely accord with the demands of hygiene, which was further confirmed by microbiological and poisonous tests and the effects of clinical application. In Nov. 1988, the dressings was awarded the excellent prize in the 1st international exhibition of patent, new technique and new equipment in Guangzhou; its effective application is also reported in the paper.

  3. Pressure Ulcer Prevention in the Hospital Setting Using Silicone Foam Dressings

    PubMed Central

    Grigson, Eileen; Patel, Maulik; Liu, Xinwei

    2016-01-01

    Patient care is of the utmost importance in the hospital setting. Bedrest and immobility during hospitalization, especially in the surgical and intensive care setting, place the patient at high risk for pressure ulcers. It is very important to prevent or notice a pressure ulcer forming due to the significant health care costs involved and patient health associated with them. Various measures are in place to prevent patients from getting pressure ulcers, but a newer material, silicone foam dressings, has been introduced as an alternative solution for the prevention of these ulcers. We review the current literature to examine whether the standard protocol or silicone material is superior to the prevention of pressure ulcer formation. We conclude that silicone foam dressings, when used as prophylactic treatment, seems very promising and may even be superior to the standard care of prevention. However, there were limitations to some studies and further research is needed to confirm the role of silicone foam dressings. PMID:27630803

  4. The purple coloration of four late 19th century silk dresses: A spectroscopic investigation.

    PubMed

    Woodhead, Andrea L; Cosgrove, Bronwyn; Church, Jeffrey S

    2016-02-01

    Prior to the 19th century the use of purple dyes for textile coloration was expensive and usually limited to royalty. The discovery of several synthetic purple dyes during the 19th century made the production of purple textiles more affordable and thus more readily available. The identification of the source of the purple coloration is of historical interest. Small yarn samples from four late 19th century silk dresses were analyzed using a combination of thin layer chromatography and surface enhanced Raman spectroscopy, Fourier transform infrared spectroscopy and energy dispersive x-ray spectroscopy. This combination of techniques enabled the analysis of the complex extraction products. While three of the dresses were found to be dyed using methyl violet, the fourth dress was found to be constructed from a warp yarn dyed with methyl violet in the presence of a tannic acid mordant, and a weft yarn dyed with mauve and a tin mordant. PMID:26523685

  5. Composite wound dressings of pectin and gelatin with aloe vera and curcumin as bioactive agents.

    PubMed

    Tummalapalli, Mythili; Berthet, Morgane; Verrier, Bernard; Deopura, B L; Alam, M S; Gupta, Bhuvanesh

    2016-01-01

    Aloe vera and curcumin loaded oxidized pectin-gelatin (OP-Gel) matrices were used as antimicrobial finishes on nonwoven cotton fabrics to produce composite wound care devices. The drug release characteristics of the biocomposite dressings indicated that curcumin is released through a biphasic mechanism - erosion of the polymeric matrix, followed by diffusion, while aloe vera is released upon leaching of the polymeric matrix. A 50/50 composition of aloe vera/curcumin was used to fabricate OP-Gel-Aloe Curcumin dressings. However, contrary to our expectations, OP-Gel-Aloe Curcumin dressings exhibited lesser antimicrobial activity compared to OP-Gel-Aloe and OP-Gel-Curcumin dressings. The cytocompatibility of the fabricated dressings was evaluated using NIH3T3 mouse fibroblast cells. OP-Gel-Aloe treated fibroblasts had the highest viability, with the matrices providing a substrate for good cell attachment and proliferation. On the other hand, OP-Gel-Curcumin and OP-Gel-Aloe Curcumin seemed to have induced apoptosis in NIH3T3 cells. In vivo wound healing analysis was carried out using an excisional splint wound model on C57BL/6J mice. OP-Gel-Aloe treated wounds exhibited very rapid healing with 80% of the wound healing in just 8 days. Furthermore, aloe vera exerted a strong anti-inflammatory effect and prominent scar prevention. Histological examination revealed that an ordered collagen formation and neovascularization could be observed along with migration of nuclei. Therefore, OP-Gel-Aloe biocomposite dressings are proposed as viable materials for effective wound management. PMID:26529192

  6. A retrospective analysis of ambulatory burn patients: focus on wound dressings and healing times

    PubMed Central

    Gravante, Gianpiero; Montone, Antonio

    2010-01-01

    INTRODUCTION In this study, we retrospectively analysed healing times of ambulatory burn patients after silver-based dressings were introduced in late December 2005, and compared the results with those obtained before. PATIENTS AND METHODS Data were collected in November–December 2005 and in January–February 2006. We excluded from the study: (i) admitted patients; (ii) patients with mixed superficial partial thickness and deep partial thickness burns; (iii) patients with full-thickness burns; and (iv) operated patients that came for follow-up. We recorded the age, sex, cause (flame vs scald), burn depth, dressings used and healing times. RESULTS We selected 347 patients corresponding to 455 burned areas (64.4% superficial and 35.6% deep; 47.7% treated in 2005 and 52.3% in 2006). During the years 2005 and 2006, there was an increase in the use of silver-based dressings (2005, 9.7%; 2006, 38.7%; chi-squared test, P < 0.001) and a decrease in the use of paraffin gauzes (2005, 66.4%; 2006, 40.3%; chi-squared test, P < 0.001). The healing time of overall burns and of superficial burns showed no significant differences between 2005 and 2006. However, in deep partial thickness burns, a significant reduction was present (2006, 19; 2005, 29 days; Student's t-test, P < 0.01). Among all dressings, paraffin gauzes had the shortest healing times in superficial burns (5 days); with silver-based dressings in deep burns, the healing times were nanocrystalline silver (16 days) and silver carboxymethylcellulose (21 days). CONCLUSIONS Results of our retrospective study would suggest that paraffin gauzes are a valuable option in superficial burns, while silver-based dressings are preferable in deep burns. PMID:19995488

  7. Economic impact of Tegaderm chlorhexidine gluconate (CHG) dressing in critically ill patients

    PubMed Central

    Thokala, Praveen; Arrowsmith, Martin; Poku, Edith; Martyn-St James, Marissa; Anderson, Jeff; Foster, Steve; Elliott, Tom; Whitehouse, Tony

    2016-01-01

    Purpose: To estimate the economic impact of a TegadermTM chlorhexidine gluconate (CHG) gel dressing compared with a standard intravenous (i.v.) dressing (defined as non-antimicrobial transparent film dressing), used for insertion site care of short-term central venous and arterial catheters (intravascular catheters) in adult critical care patients using a cost-consequence model populated with data from published sources. Material and Methods: A decision analytical cost-consequence model was developed which assigned each patient with an indwelling intravascular catheter and a standard dressing, a baseline risk of associated dermatitis, local infection at the catheter insertion site and catheter-related bloodstream infections (CRBSI), estimated from published secondary sources. The risks of these events for patients with a Tegaderm CHG were estimated by applying the effectiveness parameters from the clinical review to the baseline risks. Costs were accrued through costs of intervention (i.e. Tegaderm CHG or standard intravenous dressing) and hospital treatment costs depended on whether the patients had local dermatitis, local infection or CRBSI. Total costs were estimated as mean values of 10,000 probabilistic sensitivity analysis (PSA) runs. Results: Tegaderm CHG resulted in an average cost-saving of £77 per patient in an intensive care unit. Tegaderm CHG also has a 98.5% probability of being cost-saving compared to standard i.v. dressings. Conclusions: The analyses suggest that Tegaderm CHG is a cost-saving strategy to reduce CRBSI and the results were robust to sensitivity analyses. PMID:27582899

  8. The association between DRESS and the diminished numbers of peripheral B lymphocytes and natural killer cells.

    PubMed

    Yazicioglu, Mehtap; Elmas, Reyhan; Turgut, Burhan; Genchallac, Tugba

    2012-05-01

    Drug reaction with eosinophilia and systemic symptoms (DRESS) is a drug-induced, severe multiorgan system reaction whose exact pathogenesis remains unknown. This study aimed at evaluating specific changes in peripheral blood lymphocyte subtypes associated with DRESS during antibiotic treatment. We analyzed six patients with DRESS. A complete blood count and peripheral blood lymphocytes immunophenotyping were carried out at symptom onset and at follow-up visits. Acute-phase reactants and liver enzymes were measured in all patients. Other tests - viral serology, serum immunoglobulin levels, and skin tests were performed when possible. B-cell counts were low in all patients at the onset of DRESS, and natural killer (NK) cells were low in all cases except one. During recovery, B-cell numbers were within a normal range in five patients. In one, there was even a 10-fold increase in B-cell counts, although the level was mildly low after 3 months. NK-cell numbers were within a normal range in three patients. The mean numbers of B cells and NK cells were significantly higher in the second samples compared to the values on admission. Serum IgA and IgM levels were low in one patient. The drug provocation test was positive with cefotaxime in one patient. Viral serology, performed on five patients, was negative. A decrease in B-cell and NK-cell counts was the most consistent finding associated with the onset of antibiotic-induced DRESS in our patients. This immunologic alteration might be a useful predictor of DRESS development.

  9. Composite wound dressings of pectin and gelatin with aloe vera and curcumin as bioactive agents.

    PubMed

    Tummalapalli, Mythili; Berthet, Morgane; Verrier, Bernard; Deopura, B L; Alam, M S; Gupta, Bhuvanesh

    2016-01-01

    Aloe vera and curcumin loaded oxidized pectin-gelatin (OP-Gel) matrices were used as antimicrobial finishes on nonwoven cotton fabrics to produce composite wound care devices. The drug release characteristics of the biocomposite dressings indicated that curcumin is released through a biphasic mechanism - erosion of the polymeric matrix, followed by diffusion, while aloe vera is released upon leaching of the polymeric matrix. A 50/50 composition of aloe vera/curcumin was used to fabricate OP-Gel-Aloe Curcumin dressings. However, contrary to our expectations, OP-Gel-Aloe Curcumin dressings exhibited lesser antimicrobial activity compared to OP-Gel-Aloe and OP-Gel-Curcumin dressings. The cytocompatibility of the fabricated dressings was evaluated using NIH3T3 mouse fibroblast cells. OP-Gel-Aloe treated fibroblasts had the highest viability, with the matrices providing a substrate for good cell attachment and proliferation. On the other hand, OP-Gel-Curcumin and OP-Gel-Aloe Curcumin seemed to have induced apoptosis in NIH3T3 cells. In vivo wound healing analysis was carried out using an excisional splint wound model on C57BL/6J mice. OP-Gel-Aloe treated wounds exhibited very rapid healing with 80% of the wound healing in just 8 days. Furthermore, aloe vera exerted a strong anti-inflammatory effect and prominent scar prevention. Histological examination revealed that an ordered collagen formation and neovascularization could be observed along with migration of nuclei. Therefore, OP-Gel-Aloe biocomposite dressings are proposed as viable materials for effective wound management.

  10. A case of Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) related to rufinamide.

    PubMed

    Shahbaz, S; Sivamani, R K; Konia, T; Burrall, B

    2013-01-01

    Drug Rash (or Reaction) with Eosinophilia and Systemic Symptoms (DRESS) is a potentially life-threatening hypersensitivity reaction to drugs characterized by rash, fever, lymphadenopathy, hematologic abnormalities, and involvement of internal organs. Initially coined in 1996, the term is used to refer to an idiosyncratic reaction to several drugs, the most common of which are carbamazepine, allopurinol, sulfasalazine, and phenobarbital. We report the first case of DRESS related to rufinamide in a ten year old boy with a history of a complex seizure disorder. PMID:24021364

  11. Interaction of a probe pulse with a 'dressed' Bose-Einstein condensate of rarefied atomic gases

    SciTech Connect

    Shamrov, N I

    2008-01-31

    Semiclassical equations describing the interaction of a probe pulse with a 'dressed' Bose-Einstein condensate of a rarefied atomic gas are proposed. The analytic solution of these equations is obtained for low-intensity pulses. The conditions of the appearance of a diffraction grating from recoil atoms are found. The existence of induced superradiance at the probe-beam frequency is predicted. The pulse propagation velocity in the condensate is determined as a function of its energy. The limits of the applicability of the two-level model of a 'dressed' atom are estimated. (nonlinear optical phenomena)

  12. Lifetime Autler-Townes Splitting of Dressed Multi-order Fluorescence in Pr3+:YSO

    NASA Astrophysics Data System (ADS)

    Ali, Imran; Li, Changbiao; Hasan, Abdulkhaleq; Abdisa, Garuma; Liu, Zongchen; Ma, Feng; Zhang, Yanpeng

    2016-07-01

    For first time, we study primary and secondary Autler-Townes (AT) splitting of multi-order fluorescence (FL) in time domain. The AT-splitting of multi-order FL signals are controlled by changing power, detuning, and polarization of single and double dressing in a heteronuclear-like molecule system of Pr+3:YSO. The primary and secondary AT-splitting is caused by double cascaded dressing in time domain. The AT-splitting of multi-order FL in time domain is more sensitive than that of in spectral domain. Such results have potential applications in quantum communication and optical information processing on photonic chip.

  13. Observation of quantum interference between dressed states in an electromagnetically induced transparency

    NASA Astrophysics Data System (ADS)

    Li, Yong-Qing; Xiao, Min

    1995-06-01

    We report on an experimental observation of quantum interference between two dressed states created by a coherent pumping laser in an electromagnetically induced transparency. In a Λ-type three-level atomic system in rubidium vapor, we reduce the Rabi frequency of the pumping laser in one arm down below the spontaneous decay rate of the common excited state and still observe a narrow dip with subnatural linewidth in the absorption curve of a probe beam in another arm. This clearly demonstrates that the absorption reduction at the low pumping intensity is mainly due to the interference between the two dressed states, not due to the ac-Stark-shift effect.

  14. Utilization of optical polarization microscopy in the study of sorption characteristics of wound dressing host materials.

    PubMed

    Devetak, Miha; Peršin, Zdenka; Stana-Kleinschek, Karin; Maver, Uroš

    2014-04-01

    Polarization microscopy was used for evaluation of kinetics of diclofenac sorption in three different wound dressing materials. The sorption kinetics can be evaluated by radii change and intensity of the light traveling through the fiber. The most frequently used host materials for drugs in wound dressings are alginate, polyesters such as polyethylene terephthalate, and viscose. We studied sorption of diclofenac as an example drug. Effective, but rather simple in vitro simulation of diclofenac sorption gives insight into the applicability of the mentioned materials for development of wound healing materials.

  15. Podiatry evaluation of a chitosan gelling fibre dressing in diabetic foot ulceration.

    PubMed

    Walker, Angela

    2016-06-23

    The purpose of this small evaluation on five patients presenting to community podiatry services in Birmingham with foot ulceration was to explore common problems associated with diabetes and other high-risk conditions and illustrate the clinical effectiveness and experience of using a chitosan absorbent gelling fibre dressing (KytoCel®, Aspen Medical). Each of these case studies bought their individual complex issues and complications that affected the healing process. General wound care involved debridement, if required, dressings, pressure redistribution addressing footwear needs, systemic antibiotics where required, and shared care with the multidisciplinary team (MDT) in secondary care where appropriate. PMID:27345085

  16. Semi-permanent skin staining associated with silver-coated wound dressing Acticoat

    PubMed Central

    Zweiker, D.; Horn, S.; Hoell, A.; Seitz, S.; Walter, D.; Trop, M.

    2014-01-01

    Summary A 17-year-old male with burns to 8% of his total body surface area was treated for 10 days with Acticoat®, a nanocrystalline silver dressing. The burns, which were on his back and shoulder, healed without infection. However, a skin discoloration in the wound area and the adjacent uninjured skin appeared in the first days of treatment. The staining remained visible even after the treatment had ended and disappeared approximately three years later. Despite the outstanding antimicrobial properties, possible side effects of silver nanocrystalline dressings should be kept in mind. PMID:26336367

  17. Compressive and rarefactive dressed solitons in plasma with nonthermal electrons and positrons

    NASA Astrophysics Data System (ADS)

    Abdelwahed, H. G.; El-Shewy, E. K.; Zahran, M. A.; Elwakil, S. A.

    2016-02-01

    The study of dressed solitary ion waves in a collisionless unmagnetized plasma composed warm fluid of ion, nonthermal distributed positrons and electrons are discussed. Concerning nonlinear ion acoustic waves, a reductive perturbation method is applied to obtain the KdV equation in terms of first order potential. Our results exemplify that, if soliton amplitude enlarged, the shape of the wave sidetrack from KdV equation. In order to improve the soliton shape, the perturbed KdV equation is suggest. In particular, the effects of nonthermal positrons and ionic temperature on the electrostatic dressed rarefactive and compressive soliton structures are discussed.

  18. Observation of the three-state dressed states in circuit quantum electrodynamics.

    PubMed

    Koshino, K; Terai, H; Inomata, K; Yamamoto, T; Qiu, W; Wang, Z; Nakamura, Y

    2013-06-28

    We have investigated the microwave response of a transmon qubit coupled directly to a transmission line. In a transmon qubit, owing to its weak anharmonicity, a single driving field may generate dressed states involving more than two bare states. We confirmed the formation of three-state dressed states by observing all of the six associated Rabi sidebands, which appear as either amplification or attenuation of the probe field. The experimental results are reproduced with good precision by a theoretical model incorporating the radiative coupling between the qubit and the microwave.

  19. Dressed-state strong-field approximation for laser-induced molecular ionization

    SciTech Connect

    Becker, W.; Chen, J.; Chen, S. G.; Milosevic, D. B.

    2007-09-15

    In the customary formulation of the strong-field approximation (SFA) for laser-induced ionization, the initial bound state is taken as field-free. In the formulation of a length-gauge SFA for ionization of a molecule described by a two-center binding potential with sufficiently large internuclear separation, we argue that the initial state has to be dressed in order to account for the different scalar potentials at the various centers. We propose a 'dressed-state' SFA to this end.

  20. "Tank Tops Are Ok but I Don't Want to See Her Thong": Girls' Engagements with Secondary School Dress Codes

    ERIC Educational Resources Information Center

    Raby, Rebecca

    2010-01-01

    School conduct codes invariably include special mention of dress, often with some reference to concerns about revealing dress. Drawing on eight focus groups with secondary students in Southern Ontario, this article explores female students' responses to such dress codes. Many young women were critical of certain aspects of their schools' dress…

  1. A fatal case of DRESS induced by strontium ranelate associated with HHV-7 reactivation.

    PubMed

    Drago, F; Cogorno, L; Broccolo, F; Ciccarese, G; Parodi, A

    2016-03-01

    We report the first case of drug rash with eosinophilia and systemic symptoms (DRESS) following strontium ranelate (SR) treatment associated with systemic human HHV-7 reactivation. DRESS syndrome is a severe adverse drug-induced reaction presenting as a diffuse maculopapular skin rash with fever, hematological abnormalities (leukocytosis, eosinophilia, and/or atypical lymphocytosis), and multiorgan involvement. In our patient, diagnosis of DRESS was confirmed by the presence of six of the seven diagnostic criteria established in 2006 by the Japanese Research Committee on Severe Cutaneous Adverse Drug Reaction: maculopapular skin rash developing at least 3 weeks after starting therapy with a limited number of drugs, prolonged clinical symptoms after discontinuation of the causative drug, lymphadenopathy, fever, leukocyte abnormalities, and liver abnormalities. The diagnostic criteria of human herpesvirus (HHV)-6 reactivation have not been fulfilled in our patient, but a HHV-7 active infection was demonstrated by the presence of HHV-7 DNA and IgM in the patient's serum. In fact, in some DRESS instances, reactivation of HHVs other than HHV-6 may be detected, including HHV-7, Epstein-Barr virus (EBV), and cytomegalovirus (CMV). Our case underlines that not only HHV-6 but also HHV-7 systemic reactivation may be associated with a more severe and even fatal course of this syndrome. PMID:26519419

  2. A New Case of DRESS Syndrome Induced by Sulfasalazine and Triggered by Amoxicillin

    PubMed Central

    Girelli, Francesco; Bernardi, Simone; Gardelli, Lucia; Bassi, Bruna; Parente, Gianluca; Dubini, Alessandra; Serra, Luigi; Nizzoli, Maurizio

    2013-01-01

    Drug Rash Eosinophilia Systemic Symptoms (DRESS) syndrome is a systemic hypersensitivity reaction characterized by exfoliative dermatitis and maculopapular rash, lymphadenopathy, fever, eosinophilia, leukocytosis, and involvement of internal organs as liver, lung, heart, and kidney; the disorder starts within 2–6 weeks after taking a drug with an incidence that ranges from 1/1000 to 1/10000 exposures. Fatal cases are reported. The exact pathogenesis of DRESS syndrome is not completely understood, while it is reported that amoxicillin could trigger it in patients who are taking allopurinol, sulfasalazine, NSAIDs, carbamazepine, strontium ranelate, lisinopril, lansoprazole, and minocycline. Amoxicillin could act directly, inducing the reactivation of a viral infection (HHV 6 and EBV) with symptoms similar to DRESS syndrome or by reducing the patients' ability to detoxify the body from substances chronically taken. We describe a case of a patient admitted to our hospital for a DRESS syndrome flared after amoxicilline intake during treatment with sulfasalazine; this combination can activate severe reactions often with an insidious onset that can mimic an infectious disease. PMID:23936716

  3. Plastibell circumcision supported by a calcium-alginate fibre dressing to reduce bleeding

    PubMed Central

    Pillai, Ravisankar G.; Al Naieb, Ziad

    2015-01-01

    Objective To assess the benefit of a new technique of a Plastibell circumcision supported by a ventral calcium-alginate fibre dressing, to reduce bleeding from the frenular vessels, the commonest complication of Plastibell circumcision. Patients and methods This was a retrospective study of 200 neonates circumcised in the Royal Bahrain Hospital over a 2-year period from 2012 to 2014. They had a standard Plastibell circumcision, but a calcium-alginate fibre dressing (Hypo-sorb, Plastod, Italy) was placed over the glans and under the foreskin, to help control bleeding from the frenular vessels. Results Circumcision using the calcium-alginate fibre dressing reduced the bleeding complication rate to zero. The delayed separation of the bell was 2.9% when using the new technique and 2.5% from our previous data. There were no cases of urinary retention reported, compared to two in the previous results. Conclusion A Plastibell circumcision supported by the calcium-alginate fibre dressing was a safe technique to reduce bleeding. PMID:26413343

  4. Manual of industrial diamonds plus dressing and grinding criteria for machining superalloys

    NASA Technical Reports Server (NTRS)

    Carr, W. L.

    1968-01-01

    Manual combines the important and controlling factors for the proper selection and use of diamond stones for cutting and dressing grinding wheels. This manual is a compilation of empirical data and incorporates an original companion treatise on the physical descriptions of the diamond stones, their grading, and their applications.

  5. School Dress Codes in Post-Scarcity Japan: Contradictions and Changes

    ERIC Educational Resources Information Center

    Tamura, Yuichi

    2007-01-01

    Focusing on dress codes, this article aims at providing a better understanding of current practices of youth socialization in Japanese schools and of cultural consequences of post-scarcity on schools. Since the late 1980s, there has been a national trend among Japanese secondary schools granting students more freedom of individual expression…

  6. The Lutterloh Dress Patterns: An Unexpected Application of Polar Co-Ordinates

    ERIC Educational Resources Information Center

    Deakin, Michael A. B.

    2008-01-01

    In this article, the author describes the Lutterloh method of making dress patterns, which was developed in Germany in the 1930s. The underlying principle involves the modification of basic designs and it is claimed that it provides better fits for women of different sizes and shapes than do other commercially available patterns. The method is…

  7. Leaching of the Neonicotinoids Thiamethoxam and Imidacloprid from Sugar Beet Seed Dressings to Subsurface Tile Drains.

    PubMed

    Wettstein, Felix E; Kasteel, Roy; Garcia Delgado, Maria F; Hanke, Irene; Huntscha, Sebastian; Balmer, Marianne E; Poiger, Thomas; Bucheli, Thomas D

    2016-08-24

    Pesticide transport from seed dressings toward subsurface tile drains is still poorly understood. We monitored the neonicotinoid insecticides imidacloprid and thiamethoxam from sugar beet seed dressings in flow-proportional drainage water samples, together with spray applications of bromide and the herbicide S-metolachlor in spring and the fungicides epoxiconazole and kresoxim-methyl in summer. Event-driven, high first concentration maxima up to 2830 and 1290 ng/L for thiamethoxam and imidacloprid, respectively, were followed by an extended period of tailing and suggested preferential flow. Nevertheless, mass recoveries declined in agreement with the degradation and sorption properties collated in the groundwater ubiquity score, following the order bromide (4.9%), thiamethoxam (1.2%), imidacloprid (0.48%), kresoxim-methyl acid (0.17%), S-metolachlor (0.032%), epoxiconazole (0.013%), and kresoxim-methyl (0.003%), and indicated increased leaching from seed dressings compared to spray applications. Measured concentrations and mass recoveries indicate that subsurface tile drains contribute to surface water contamination with neonicotinoids from seed dressings. PMID:27529118

  8. Gender Dysphoria and Cross-Dressing in People with Intellectual Disability: A Literature Review

    ERIC Educational Resources Information Center

    Parkes, Georgina; Hall, Ian

    2006-01-01

    In clinical practice, we have come across people with intellectual disability who have gender dysphoria and cross-dress. Here, we review the literature on this subject and present an illustrative case example. We searched databases, followed-up references from relevant articles, and contacted colleagues in the field. We found nine papers with case…

  9. Time-resolved Absorption Spectra of the Laser-dressed Hydrogen Atom

    NASA Astrophysics Data System (ADS)

    Murakami, Mitsuko; Chu, Shih-I.

    2013-05-01

    A theoretical study of the transient absorption spectra for the laser-dressed hydrogen atom based on the accurate numerical solution of the time-dependent Schrödinger equation is presented. The timing of absorption is controlled by the time delay between an isolated extreme ultraviolet (XUV) pulse and a dressing infrared (IR) field. We identify two different kinds of physical processes in the spectra. One is the formation of dressed states, signified by the appearance of sidebands between the XUV absorption lines separated by one IR-photon energy. We show that their population is maximized when the XUV pulse coincides with the zero-crossing of the IR field, and that their energy can be manipulated by using a chirped IR field. The other process is the dynamical AC Stark shift induced by the IR field and probed by the XUV pulse. Our calculations indicate that the accidental degeneracy of the hydrogen atom leads to the multiple splittings of each XUV absorption line whose separations change in response to a slowly-varying IR envelope. Furthermore, we observe the Autler-Townes doublets for the n=2 and 3 states using the 656 nm dressing field, but their separation does not agree with the prediction by the conventional 3-level model that neglects the dynamical AC Stark effects.

  10. Evaluation of hemostatic field dressing for bacteria, mycobacteria, or fungus contamination.

    PubMed

    Murray, Clinton K; Brunstetter, Tyson; Beckius, Miriam; Dunne, James R; Mende, Katrin

    2013-03-01

    Infectious complications have a major impact on wounded warriors. Pathogens causing infections include multidrug-resistant bacteria, fungi, and mycobacteria. The potential sources for these pathogens include nosocomial transmission, the environment (e.g., dirt), or the patients (skin flora) themselves. The purpose of this pilot study was to explore the possibility that hemostatic field dressings might act as an inoculation source of pathogens into wounds. To accomplish this, hemostatic field dressings were assessed for the presence of bacterial, fungal, or mycobacterial contamination. We evaluated two samples of QuikClot Combat Gauze and two samples of CELOX Gauze subjected to normal stresses associated with storage after receipt from the manufacturer. We then evaluated 16 samples of QuikClot Combat Gauze that were collected from personnel deployed in Afghanistan and had undergone routine mechanical stress. Samples underwent screening with Trypticase Soy Broth, blood agar plates, MacConkey agar plates, CHROMagar Staphylococcus aureus plates, chocolate agar plates, Potato Flake agar, Lowenstein-Jensen media, and Middlebrook 7H11 media. No bacteria, fungi, or mycobacteria were recovered from the dressings. It does not appear that hemostatic field dressings are contaminated, even after subjected to field conditions. Further research is needed to identify inoculation sources of fungi and mycobacteria, which cause infections.

  11. Protease inhibition by oleic acid transfer from chronic wound dressings to albumin.

    PubMed

    Edwards, J Vincent; Howley, Phyllis; Davis, Rachel; Mashchak, Andrew; Goheen, Steven C

    2007-08-01

    High elastase and cathepsin G activities have been observed in chronic wounds to inhibit healing through degradation of growth factors, cytokines, and extracellular matrix proteins. Oleic acid is a non-toxic elastase inhibitor. Cotton wound dressing material was characterized as a transfer carrier for affinity uptake of oleic acid by albumin under conditions mimicking chronic wounds. The mechanism of oleic acid uptake from cotton and binding by albumin was examined with both intact dressings and cotton fiber-designed chromatography. Raman spectra of the albumin-oleic acid complexes under liquid equilibrium conditions revealed fully saturated albumin-oleic acid complexes with a 1:1 weight ratio of albumin:oleic acid. Liquid-solid equilibrium conditions revealed oleic acid transfer from cotton to albumin at 27 mole equivalents of oleic acid per mole albumin. Comparing oleic acid formulated wound dressings for dose dependent ability to lower elastase activity, we found cotton gauze>hydrogel>hydrocolloid. In contrast, the cationic serine protease cathepsin G was inhibited by oleic acid within a narrow range of oleic acid-cotton formulations. 2% albumin was sufficient to transfer quantities of oleic acid necessary to achieve a significant elastase-lowering effect. Oleic acid bound to cotton wound dressings may have promise in the selective lowering of cationic serine protease activity useful in topical application for chronic inflammatory pathogenesis.

  12. Wound dressings based on silver sulfadiazine solid lipid nanoparticles for tissue repairing.

    PubMed

    Sandri, Giuseppina; Bonferoni, Maria Cristina; D'Autilia, Francesca; Rossi, Silvia; Ferrari, Franca; Grisoli, Pietro; Sorrenti, Milena; Catenacci, Laura; Del Fante, Claudia; Perotti, Cesare; Caramella, Carla

    2013-05-01

    The management of difficult to heal wounds can considerably reduce the time required for tissue repairing and promote the healing process, minimizing the risk of infection. Silver compounds, especially silver sulfadiazine (AgSD), are often used to prevent or to treat wound colonization, also in presence of antibiotic-resistant bacteria. However, AgSD has been shown to be cytotoxic in vitro toward fibroblasts and keratinocytes and consequently to retard wound healing in vivo. Recently, platelet lysate (PL) has been proposed in clinical practice for the healing of persistent lesions. The aim of the present work was the development of wound dressings based on AgSD loaded in solid lipid nanoparticles (SLNs), to be used in association with PL for the treatment for skin lesions. SLN were based on chondroitin sulfate and sodium hyaluronate, bioactive polymers characterized by well-known tissue repairing properties. The encapsulation of AgSD in SLN aimed at preventing the cytotoxic effect of the drug on normal human dermal fibroblasts (NHDFs) and at enabling the association of the drug with PL. SLN were loaded in wound dressings based on hydroxypropylmethyl cellulose (HPMC) or chitosan glutamate (CS glu). These polymers were chosen to obtain a sponge matrix with suitable elasticity and softness and, moreover, with good bioadhesive behavior on skin lesions. Dressings based on chitosan glutamate showed antimicrobial activity with and without PL. Even though further in vivo evaluation could be envisaged, chitosan based dressings demonstrated to be a suitable prototype for the treatment for skin lesions.

  13. [Study on the volume flows through polymeric membranous dressing with silver ions].

    PubMed

    Slezak, Andrzej; Grzegorczyn, Sławomir; Slezak, Izabella H; Kucharzewski, Marek

    2006-01-01

    The volume flows through double-layer polymeric membranous dressing, formed by three types of theromoplastic polymeric fibers called Textus Bioactive were studied. The first layer contains two types of fibers: the polymeric fibers containing hydrophobic core and hydrophilic surfaces with silver zeolite and hydrophilic super absorbing polymers (SAP). The second layer of membrane contains third type of polymeric fibers, arranged parallel to surface's skin, creating a net, which prevents membranous dressing from sticking to treated wound. The pressure characteristics of the volume flux were determined and it was stated that the value of this flux is dependent on the value of hydrostatic pressure difference (deltaP) and the concentration difference (deltaC) of solutions separated by membrane. Experimental results show that the membranous dressing Textus Bioactive posses the rectifying properties with reference to volume flows. These properties occurs above a threshold value of deltaC. Using the Kedem-Katchalsky equations, the model of the volume flows through membranous dressing Textus Bioactive was made.

  14. Idiopathic calcinosis cutis in fingertip treated with occlusive dressing using aluminum foil: a case report.

    PubMed

    Sato, Kazuki; Nakamura, Toshiyasu; Toyama, Yoshiaki; Ikegami, Hiroyasu; Kameyama, Kaori; Takayama, Shinichiro

    2007-01-01

    Calcium deposition in the skin, known as calcinosis cutis, is an uncommon disorder caused by an abnormal deposit of calcium phosphate in the skin. We report a case of idiopathic calcinosis cutis in fingertip treated with surgical excision followed by the occlusive dressing using aluminum foil, and obtained significant pain relief and round-shaped fingertip which looked normal.

  15. Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds.

    PubMed

    Kotz, Paula; Fisher, Jane; McCluskey, Pat; Hartwell, Samantha D; Dharma, Hussein

    2009-06-01

    Recognising and managing wounds at risk of infection is vital in wound management. ALLEVYN Ag dressings have been designed to manage exudate in chronic wounds that are at risk of infection; are displaying signs of local infection; or where a suspected increase in bacterial colonisation is delaying healing. They combine an absorbent silver sulfadiazine containing hydrocellular foam layer, with a perforated wound contact layer and highly breathable top film. The results presented are from a multi-centre clinical evaluation of 126 patients conducted to assess the performance of ALLEVYN Ag (Adhesive, Non Adhesive and Sacrum dressings) in a range of indications. Clinicians rated the dressings as acceptable for use in various wound types in 88% of patients. The majority of clinical signs of infection reduced between the initial and the final assessment. The condition of wound tissue and surrounding skin was observed to improve, and there was significant evidence of a reduction in the level of exudate from initial to final assessment (p < 0.001). Clinicians rated ALLEVYN Ag as satisfying or exceeding expectations in over 90% of patients. The evaluation showed the dressings to offer real benefits to patients and clinicians across multiple indications when used in conjunction with local protocols.

  16. Formulation of Novel Layered Sodium Carboxymethylcellulose Film Wound Dressings with Ibuprofen for Alleviating Wound Pain

    PubMed Central

    Vinklárková, Lenka; Vetchý, David; Bernatonienė, Jurga

    2015-01-01

    Effective assessment and management of wound pain can facilitate both improvements in healing rates and overall quality of life. From a pharmacological perspective, topical application of nonsteroidal anti-inflammatory drugs in the form of film wound dressings may be a good choice. Thus, the aim of this work was to develop novel layered film wound dressings containing ibuprofen based on partially substituted fibrous sodium carboxymethylcellulose (nonwoven textile Hcel NaT). To this end, an innovative solvent casting method using a sequential coating technique has been applied. The concentration of ibuprofen which was incorporated as an acetone solution or as a suspension in a sodium carboxymethylcellulose dispersion was 0.5 mg/cm2 and 1.0 mg/cm2 of film. Results showed that developed films had adequate mechanical and swelling properties and an advantageous acidic surface pH for wound application. An in vitro drug release study implied that layered films retained the drug for a longer period of time and thus could minimize the frequency of changing the dressing. Films with suspended ibuprofen demonstrated higher drug content uniformity and superior in vitro drug release characteristics in comparison with ibuprofen incorporation as an acetone solution. Prepared films could be potential wound dressings for the effective treatment of wound pain in low exuding wounds. PMID:26090454

  17. An investigation of Pseudomonas aeruginosa biofilm growth on novel nanocellulose fibre dressings.

    PubMed

    Powell, Lydia C; Khan, Saira; Chinga-Carrasco, Gary; Wright, Chris J; Hill, Katja E; Thomas, David W

    2016-02-10

    Nanocellulose from wood is a novel biomaterial, which is highly fibrillated at the nanoscale. This affords the material a number of advantages, including self-assembly, biodegradability and the ability to absorb and retain moisture, which highlights its potential usefulness in clinical wound-dressing applications. In these in vitro studies, the wound pathogen Pseudomonas aeruginosa PAO1 was used to assess the ability of two nanocellulose materials to impair bacterial growth (<48 h). The two nanocelluloses had a relatively small fraction of residual fibres (<4%) and thus a large fraction of nanofibrils (widths <20 nm). Scanning electron microscopy and confocal laser scanning microscopy imaging demonstrated impaired biofilm growth on the nanocellulose films and increased cell death when compared to a commercial control wound dressing, Aquacel(®). Nanocellulose suspensions inhibited bacterial growth, whilst UV-vis spectrophotometry and laser profilometry also revealed the ability of nanocellulose to form smooth, translucent films. Atomic force microscopy studies of the surface properties of nanocellulose demonstrated that PAO1 exhibited markedly contrasting morphology when grown on the nanocellulose film surfaces compared to an Aquacel(®) control dressing (p<0.05). This study highlights the potential utility of these biodegradable materials, from a renewable source, for wound dressing applications in the prevention and treatment of biofilm development. PMID:26686120

  18. Evaluation of hemostatic field dressing for bacteria, mycobacteria, or fungus contamination.

    PubMed

    Murray, Clinton K; Brunstetter, Tyson; Beckius, Miriam; Dunne, James R; Mende, Katrin

    2013-03-01

    Infectious complications have a major impact on wounded warriors. Pathogens causing infections include multidrug-resistant bacteria, fungi, and mycobacteria. The potential sources for these pathogens include nosocomial transmission, the environment (e.g., dirt), or the patients (skin flora) themselves. The purpose of this pilot study was to explore the possibility that hemostatic field dressings might act as an inoculation source of pathogens into wounds. To accomplish this, hemostatic field dressings were assessed for the presence of bacterial, fungal, or mycobacterial contamination. We evaluated two samples of QuikClot Combat Gauze and two samples of CELOX Gauze subjected to normal stresses associated with storage after receipt from the manufacturer. We then evaluated 16 samples of QuikClot Combat Gauze that were collected from personnel deployed in Afghanistan and had undergone routine mechanical stress. Samples underwent screening with Trypticase Soy Broth, blood agar plates, MacConkey agar plates, CHROMagar Staphylococcus aureus plates, chocolate agar plates, Potato Flake agar, Lowenstein-Jensen media, and Middlebrook 7H11 media. No bacteria, fungi, or mycobacteria were recovered from the dressings. It does not appear that hemostatic field dressings are contaminated, even after subjected to field conditions. Further research is needed to identify inoculation sources of fungi and mycobacteria, which cause infections. PMID:23707133

  19. Effects of Performer Attractiveness, Stage Behavior, and Dress on Evaluation of Children's Piano Performances.

    ERIC Educational Resources Information Center

    Wapnick, Joel; Mazza, Jolan Kovacs; Darrow, Alice Ann

    2000-01-01

    Examines whether selected nonmusical attributes of 20 sixth-grade pianists would affect ratings of their performances by 123 musically trained evaluators. States that the visual group evaluators viewed a videotape, without the sound, rating the pianists on appropriateness of dress, stage behavior, and physical attractiveness. The audio and…

  20. Anti-biofilm and cytotoxicity activity of impregnated dressings with silver nanoparticles.

    PubMed

    Velázquez-Velázquez, Jorge Luis; Santos-Flores, Andrés; Araujo-Meléndez, Javier; Sánchez-Sánchez, Roberto; Velasquillo, Cristina; González, Carmen; Martínez-Castañon, Gabriel; Martinez-Gutierrez, Fidel

    2015-04-01

    Infections arising from bacterial adhesion and colonization on chronic wounds are a significant healthcare problem. Silver nanoparticles (AgNPs) impregnated in dressing have attracted a great deal of attention as a potential solution. The goal of the present study was to evaluate the anti-biofilm activities of AgNPs impregnated in commercial dressings against Pseudomonas aeruginosa, bacteria isolated of chronic wounds from a hospital patient. The antimicrobial activity of AgNPs was tested within biofilms generated under slow fluid shear conditions using a standard bioreactor. A 2-log reduction in the number of colony-forming units of P. aeruginosa was recorded in the reactor on exposure to dressing impregnated with 250ppm of AgNPs, diameter 9.3±1.1nm, and also showed compatibility to mammalian cells (human fibroblasts). Our study suggests that the use of dressings with AgNPs may either prevent or reduce microbial growth in the wound environment, and reducing wound bioburden may improve wound-healing outcomes.

  1. Dressed Gain from the Parametrically Amplified Four-Wave Mixing Process in an Atomic Vapor

    PubMed Central

    Zhang, Zhaoyang; Wen, Feng; Che, Junling; Zhang, Dan; Li, Changbiao; Zhang, Yanpeng; Xiao, Min

    2015-01-01

    With a forward cone emitting from the strong pump laser in a thermal rubidium atomic vapor, we investigate the non-degenerate parametrically amplified four-wave mixing (PA-FWM) process with dressing effects in a three-level “double-Λ” configuration both theoretically and experimentally. By seeding a weak probe field into the Stokes or anti-Stokes channel of the FWM, the gain processes are generated in the bright twin beams which are called conjugate and probe beams, respectively. However, the strong dressing effect of the pump beam will dramatically affect the gain factors both in the probe and conjugate channels, and can inevitably impose an influence on the quantum effects such as entangled degree and the quantum noise reduction between the two channels. We systematically investigate the intensity evolution of the dressed gain processes by manipulating the atomic density, the Rabi frequency and the frequency detuning. Such dressing effects are also visually evidenced by the observation of Autler-Townes splitting of the gain peaks. The investigation can contribute to the development of quantum information processing and quantum communications. PMID:26463588

  2. Using a soft silicone-coated net dressing to manage skin tears.

    PubMed

    Meuleneire, F

    2002-11-01

    Traditional management of skin tears can cause new damage and slow down healing. This paper discusses how to categorise these acute wounds and the significance of a study that used a soft silicone-coated net dressing on patients in a Belgian hospital.

  3. Leaching of the Neonicotinoids Thiamethoxam and Imidacloprid from Sugar Beet Seed Dressings to Subsurface Tile Drains.

    PubMed

    Wettstein, Felix E; Kasteel, Roy; Garcia Delgado, Maria F; Hanke, Irene; Huntscha, Sebastian; Balmer, Marianne E; Poiger, Thomas; Bucheli, Thomas D

    2016-08-24

    Pesticide transport from seed dressings toward subsurface tile drains is still poorly understood. We monitored the neonicotinoid insecticides imidacloprid and thiamethoxam from sugar beet seed dressings in flow-proportional drainage water samples, together with spray applications of bromide and the herbicide S-metolachlor in spring and the fungicides epoxiconazole and kresoxim-methyl in summer. Event-driven, high first concentration maxima up to 2830 and 1290 ng/L for thiamethoxam and imidacloprid, respectively, were followed by an extended period of tailing and suggested preferential flow. Nevertheless, mass recoveries declined in agreement with the degradation and sorption properties collated in the groundwater ubiquity score, following the order bromide (4.9%), thiamethoxam (1.2%), imidacloprid (0.48%), kresoxim-methyl acid (0.17%), S-metolachlor (0.032%), epoxiconazole (0.013%), and kresoxim-methyl (0.003%), and indicated increased leaching from seed dressings compared to spray applications. Measured concentrations and mass recoveries indicate that subsurface tile drains contribute to surface water contamination with neonicotinoids from seed dressings.

  4. Use of Aeromonas as a process indicator during swine carcass dressing and cutting

    NASA Astrophysics Data System (ADS)

    Palumbo, Samuel A.; Yu, Linda S. L.

    1999-01-01

    Using starch ampicillin agar, qualitative and quantitative determinations of Aeromonas spp. were made at several sites during swine carcass dressing and cutting. Aeromonas spp. were observed at all sites surveyed. Levels increased during shackling and passage through the first and middle polisher/washers, and significantly decreased during the singeing steps. Passage through the final polisher/washer caused a small increase in levels in Aeromonas spp. and these levels then remained constant during the rest of the carcass dressing operation. Aeromonas spp. were also isolated from the room where the carcasses were cut into wholesale cuts and cuts for further processing. Presumptive Aeromonas spp. cultures isolated from the different sites were confirmed as belonging to the genus Aeromonas and then speciated using the biochemical scheme of Joseph and Carnahan; 81% of the cultures were identified at A. hydrophila. Since most isolates were A. hydrophila, determination of the origin of isolates from different sites in the processing plant must await utilizing molecular biotyping techniques on the cultures. These results indicate the Aeromonas spp. occurs extensively in the swine dressing environment and thus represents a possible public health hazard and potential spoilage concern. Changes in cleaning and sanitizing of equipment may be necessary during swine carcass dressing and cutting to guard against this pathogen.

  5. Dressed Gain from the Parametrically Amplified Four-Wave Mixing Process in an Atomic Vapor.

    PubMed

    Zhang, Zhaoyang; Wen, Feng; Che, Junling; Zhang, Dan; Li, Changbiao; Zhang, Yanpeng; Xiao, Min

    2015-01-01

    With a forward cone emitting from the strong pump laser in a thermal rubidium atomic vapor, we investigate the non-degenerate parametrically amplified four-wave mixing (PA-FWM) process with dressing effects in a three-level "double-Λ" configuration both theoretically and experimentally. By seeding a weak probe field into the Stokes or anti-Stokes channel of the FWM, the gain processes are generated in the bright twin beams which are called conjugate and probe beams, respectively. However, the strong dressing effect of the pump beam will dramatically affect the gain factors both in the probe and conjugate channels, and can inevitably impose an influence on the quantum effects such as entangled degree and the quantum noise reduction between the two channels. We systematically investigate the intensity evolution of the dressed gain processes by manipulating the atomic density, the Rabi frequency and the frequency detuning. Such dressing effects are also visually evidenced by the observation of Autler-Townes splitting of the gain peaks. The investigation can contribute to the development of quantum information processing and quantum communications. PMID:26463588

  6. Dressing in Costume and the Use of Alcohol, Marijuana, and Other Drugs by College Students.

    ERIC Educational Resources Information Center

    Miller, Kimberly A.; And Others

    1993-01-01

    Compared behavior of college students who wore costumes on Halloween with those who did not. Findings from 805 females and 448 males surveyed over 5-year period revealed significant associations between dressing in costume and drinking alcohol and between masquerading with group and using marijuana and other drugs. Found no significant…

  7. An investigation of Pseudomonas aeruginosa biofilm growth on novel nanocellulose fibre dressings.

    PubMed

    Powell, Lydia C; Khan, Saira; Chinga-Carrasco, Gary; Wright, Chris J; Hill, Katja E; Thomas, David W

    2016-02-10

    Nanocellulose from wood is a novel biomaterial, which is highly fibrillated at the nanoscale. This affords the material a number of advantages, including self-assembly, biodegradability and the ability to absorb and retain moisture, which highlights its potential usefulness in clinical wound-dressing applications. In these in vitro studies, the wound pathogen Pseudomonas aeruginosa PAO1 was used to assess the ability of two nanocellulose materials to impair bacterial growth (<48 h). The two nanocelluloses had a relatively small fraction of residual fibres (<4%) and thus a large fraction of nanofibrils (widths <20 nm). Scanning electron microscopy and confocal laser scanning microscopy imaging demonstrated impaired biofilm growth on the nanocellulose films and increased cell death when compared to a commercial control wound dressing, Aquacel(®). Nanocellulose suspensions inhibited bacterial growth, whilst UV-vis spectrophotometry and laser profilometry also revealed the ability of nanocellulose to form smooth, translucent films. Atomic force microscopy studies of the surface properties of nanocellulose demonstrated that PAO1 exhibited markedly contrasting morphology when grown on the nanocellulose film surfaces compared to an Aquacel(®) control dressing (p<0.05). This study highlights the potential utility of these biodegradable materials, from a renewable source, for wound dressing applications in the prevention and treatment of biofilm development.

  8. Use of a new silver barrier dressing, ALLEVYN◊ Ag in exuding chronic wounds

    PubMed Central

    Kotz, Paula; Fisher, Jane; McCluskey, Pat; Hartwell, Samantha D; Dharma, Hussein

    2009-01-01

    Recognising and managing wounds at risk of infection is vital in wound management. ALLEVYN Ag dressings have been designed to manage exudate in chronic wounds that are at risk of infection; are displaying signs of local infection; or where a suspected increase in bacterial colonisation is delaying healing. They combine an absorbent silver sulfadiazine containing hydrocellular foam layer, with a perforated wound contact layer and highly breathable top film. The results presented are from a multi-centre clinical evaluation of 126 patients conducted to assess the performance of ALLEVYN Ag (Adhesive, Non Adhesive and Sacrum dressings) in a range of indications. Clinicians rated the dressings as acceptable for use in various wound types in 88% of patients. The majority of clinical signs of infection reduced between the initial and the final assessment. The condition of wound tissue and surrounding skin was observed to improve, and there was significant evidence of a reduction in the level of exudate from initial to final assessment (p < 0.001). Clinicians rated ALLEVYN Ag as satisfying or exceeding expectations in over 90% of patients. The evaluation showed the dressings to offer real benefits to patients and clinicians across multiple indications when used in conjunction with local protocols. PMID:19538192

  9. LINGAM AS A SACRED OBJECT AND THE HEAD-DRESS OF SUFI RESEMBLING IT

    PubMed Central

    Mahdihassan, S.

    1990-01-01

    This study scans into past of ancient man and discusses meticulously how the reproductive organ Lingam became sacred object to Hindus and why a sufi wore a phallus shaped head-dress resembling to it. In this manner the author demystifies here the procreation, the law of nature. PMID:22557692

  10. Efficacy of Polyhexamethylene Biguanide-containing Antimicrobial Foam Dressing Against MRSA Relative to Standard Foam Dressing.

    PubMed

    Kirker, Kelly R; Fisher, Steve T; James, Garth A; McGhee, Diane; Shah, Chirag B

    2009-09-01

      Many modern foam wound dressings possess a variety of attributes that are designed to create a supportive wound-healing environment. These attributes include absorbing exudate, providing optimum moisture balance at the wound surface, and preventing maceration of surrounding tissue. However, studies suggest that controlling wound bioburden should also be targeted when developing wound therapeutics. Thus, traditional foam dressings may absorb a copious amount of fluid, but may also provide an environment where microbes can grow unchallenged, leading to an increase in wound bioburden. However, antimicrobial foam dressings may prevent or reduce microbial growth, increasing the potential for wound healing. Studies reported herein evaluated the efficacy of 0.5% polyhexamethylene biguanide (PHMB) treated dressings to prevent the growth of methicillin-resistant Staphylococcus aureus (MRSA). An antimicrobial foam (Kendall™ AMD, Covidien, Mansfield, MA), which contains PHMB and a standard foam dressing (Copa™, Covidien, Mansfield, MA), which contains no PHMB (control), were directly inoculated with clinical isolate of MRSA and placed on a growth medium for selected time intervals. The presence or absence of microbial growth was quantified using plate counts and was visually assessed using scanning electron microscopy. At all time points, the antimicrobial foam dressing significantly reduced the MRSA growth compared to the control dressing. Similar results were also obtained in the microscopic evaluations. .

  11. Ward nurses' use of wound dressings before and after a bespoke education programme.

    PubMed

    Smith, G; Greenwood, M; Searle, R

    2010-09-01

    A survey of ward nurses in medical, surgical, orthopaedic and rehabilitation specialties in relation to their care of wounds and their choice and use of wound dressings was carried out in May and August 2009 at St Mary's Hospital. Isle of Wight, UK. The objectives were to find out the distribution of wound types, and their characteristics, that were treated by ward nurses in the hospital, and to assess clinical practice in the use of wound dressings, before and after a bespoke programme of education and training. A visual framework to aid the ward nurses in the choice of dressings and frequency of change was introduced after the May 2009 survey. Following the nurses' education and training programme a repeat survey, using the same methodology, was conducted in August 2009. In the initial survey, 172 wounds were included (mean number of wounds per patient 1.64) and in the repeat one, 159 (mean number of wounds per patient 1.54). In both phases of the survey, the most common wound type was pressure ulcers, followed by surgical wounds; over 60% of the wounds were pressure ulcers, of which around half were category 1, and one-third were category 2. No category 4 ulcers were recorded. About one-third of the wounds had a duration of more than 21 days. On average, wound dressings were left in place for between two and three days, with 35% of dressings being changed on a daily basis. The mean cost of dressings per wound per week was observed to be lower in the repeat survey than in the initial one (£9.02 and £11.23 respectively). The number of undesirable reasons for changing the dressing was lower in the second phase than the first. The methodology of the surveys provided meaningful and valuable results over a short timescale, and increased understanding of wound types, their characteristics, and clinical practice. The surveys showed that data that can be collected in a short period using a simple tool can yield complex and revealing data trends. They also showed that

  12. Microbiological safety of mayonnaise, salad dressings, and sauces produced in the United States: a review.

    PubMed

    Smittle, R B

    2000-08-01

    The literature on the death and survival of foodborne pathogens in commercial mayonnaise, dressing, and sauces was reviewed and statistically analyzed with emphasis on Salmonella, Escherichia coli O157:H7, and Listeria monocytogenes. The absence of reports of foodborne illness associated directly with the consumption of commercially prepared acidic dressings and sauces is evidence of their safety. Salmonella, E. coli O157:H7, E. coli, L. monocytogenes, Staphylococcus aureus, and Yersinia enterocolitica die when inoculated into mayonnaise and dressings. Historically, mayonnaise and dressings have been exempt from the acidified food regulations and have justly deserved this status due primarily to the toxic effect of acetic and to a lesser extent lactic and citric acids. These organic acids are inimical to pathogenic bacteria and are effective natural preservatives with acetic being the most effective in killing pathogenic bacteria at the pH values encountered in these products. Statistical analysis on data reported in the literature shows that the most important and significant factor in destroying pathogenic bacteria is pH as adjusted with acetic acid followed by the concentration of acetic acid in the water phase. The reported highest manufacturing target pH for dressings and sauces is 4.4, which is below the 4.75 pKa of acetic acid and below the reported inhibitory pH of 4.5 for foodborne pathogens in the presence of acetic acid. The overall conclusion is that these products are very safe. They should remain exempt from the acidified food regulations providing adequate research has been done to validate their safety, and the predominant acid is acetic and reasonable manufacturing precautions are taken.

  13. Custom-fit polymeric membrane dressing masks in the treatment of second degree facial burns.

    PubMed

    Weissman, Oren; Hundeshagen, Gabriel; Harats, Moti; Farber, Nimrod; Millet, Eran; Winkler, Eyal; Zilinsky, Isaac; Haik, Josef

    2013-09-01

    Second degree facial burns usually impart high wound site pain levels and patient discomfort due to the abundance of facial sensory innervation, as well as the development of edema and inflammation that accompany wound healing. Frequent changing of adherent dressings causes additional procedural pain and may prolong healing due to recurring damage to the wound bed. We applied face masks, made on-site from a drug free polymeric membrane dressing, to 8 patients with superficial and deep 2nd degree facial burns. Time to full re-epithlialization was recorded during treatment. Pain, overall comfort, and result satisfaction were evaluated using a questionnaire (10-point Likert scales. From 1=minimum to 10=maximum) on follow-up (mean follow up 14.4 months, range 9-18). These results were compared to a historical cohort of patients with facial burns that were treated with an antibiotic ointment. Results showed mean re-epithelialization time of 6.5 days (as compared to 8.5 days in the cohort group), low pain ratings (mean: 2.6; range: 4.7 in the control group), mixed comfort levels (mean: 4.7/10; 4 in the control group) and high result satisfaction (mean: 7.8; 6.2 in the control group). Nursing staff described pain-free dressing changes and positively noted non-adherence and high absorbance capacity of the polymer, necessitating less dressing changes. Inflammation was contained to the actual site of injury. No complications in terms of infection or allergic reaction were observed. Overall, the polymeric membrane facial dressing seems to be a promising means of reducing pain and ensuring uninterrupted wound healing in 2nd degree facial burns.

  14. Evaluation of an antimicrobial silver foam dressing for use with V.A.C. therapy: morphological, mechanical, and antimicrobial properties.

    PubMed

    Payne, Joanna L; Ambrosio, Archel M

    2009-04-01

    The V.A.C. Therapy System (KCI, San Antonio, TX) is an integrated wound management system that creates an environment that promotes wound healing. V.A.C. GranuFoam Silver dressing (S-ROCF) is a reticulated, open-celled polyurethane foam having a pore size range of 400-600 microm. The foam is coated with silver to impart antimicrobial properties throughout the dressing. The morphological and key mechanical properties including tensile strength, ultimate elongation, tear strength, and compression resistance of this dressing were compared to the original V.A.C. GranuFoam dressing (ROCF), which is also a reticulated, open-celled polyurethane foam, and were found to be comparable. Furthermore, the antimicrobial property of S-ROCF was evaluated in vitro for efficacy against pathogens commonly found in clinical settings, including Staphylococcus aureus and Pseudomonas aeruginosa. S-ROCF was found to be effective during antimicrobial testing with a 99.99% reduction in colony forming units, and remained effective after 72 h of simulated V.A.C. Therapy. The antimicrobial and mechanical characteristics of the foam were unaffected by aging as demonstrated through an accelerated aging process. The V.A.C. GranuFoam Silver dressing is a specialized antimicrobial dressing for use with the V.A.C. Therapy System that exhibits morphological and mechanical properties comparable to the V.A.C. GranuFoam dressing and provides the added benefit of antimicrobial efficacy.

  15. Thermoresponsive polyurethane/siloxane membrane for wound dressing and cell sheet transplantation: In-vitro and in-vivo studies.

    PubMed

    Rezapour-Lactoee, Alireza; Yeganeh, Hamid; Ostad, Seyed Nasser; Gharibi, Reza; Mazaheri, Zohreh; Ai, Jafar

    2016-12-01

    Polyurethane/siloxane based wound dressing for transferring fibroblast cell sheet to wounded skin and ability to provide an optimum condition for cellular activity at damaged tissue was prepared in this research. The dressing was made thermoresponsive, via the introduction of a poly(N-isopropyl acrylamide) copolymer into the backbone of dressing. The ability of membrane for adhesion, growth, and proliferation of fibroblast cells was improved via surface modification with gelatin. The optimized dressing exhibited appropriate tensile strength (4.5MPa) and elongation at break (80%) to protect wound against physical forces. Due to controlled equilibrium water absorption of about 89% and water vapor transmission rate of 2040g/m(2)day, the dressing could maintain the favorable moist environment over moderate to high exuding wounds. The grown cell sheet on dressing membrane could easily roll up from the surface just with lowering the temperature. The in vivo study of the wound dressed with cell loaded membrane confirmed the accelerated healing and production of tissue with complete re-epithelization, enhanced vascularization, and increased collagen deposition on the damaged area. PMID:27612775

  16. Early pressure dressing for the prevention of subdural effusion secondary to decompressive craniectomy in patients with severe traumatic brain injury.

    PubMed

    Xu, Gang-Zhu; Li, Wen; Liu, Kai-Ge; Wu, Wei; Lu, Wen-Chao; Zhang, Jun-Feng; Wang, Mao-De

    2014-09-01

    This study was performed to investigate the effect of early pressure dressing on the prevention of postoperative subdural effusion secondary to decompressive craniectomy (DC) in patients with severe traumatic brain injury (STBI). Patients with STBI who had undergone DC for refractory increased intracranial pressure between January 2008 and December 2011 (n = 169) were randomly divided into early pressure dressing (n = 82) and control (n = 87) groups. Early pressure dressing with an elastic bandage or general wrapping (control treatment) was applied 7 to 10 days after DC. Patients' age, sex, preoperative Glasgow Coma Scale score, incidence rate of subdural effusion, hospitalization time, and postoperative Glasgow Outcome Scale score were compared between groups. Intracranial pressure was measured immediately before and on the day after pressure dressing. No significant difference in age, sex, preoperative Glasgow Coma Scale score, or postoperative Glasgow Outcome Scale score was observed between groups (P > 0.05). Subdural effusion incidence rates were significantly lower in the early pressure dressing group than those in the control group (χ² = 5.449, P = 0.021), and a larger proportion of patients in the early pressure dressing group was hospitalized for 30 days or less (χ² = 5.245, P = 0.027). Early pressure dressing 7 to 10 days after DC, which is a noninvasive, simple procedure, reduced the incidence rate of subdural effusion and shortened hospitalization time after DC for STBI.

  17. Evaluation of a wound dressing composed of hyaluronic acid and collagen sponge containing epidermal growth factor in diabetic mice.

    PubMed

    Kondo, Shinya; Niiyama, Hayato; Yu, Akane; Kuroyanagi, Yoshimitsu

    2012-01-01

    This study investigated the effect of a wound dressing composed of hyaluronic acid (HA) and collagen (Col) sponge containing epidermal growth factor (EGF) on wound healing in diabetic mice. High-molecular-weight (HMW) HA aqueous solution, hydrolyzed low-molecular-weight (LMW) HA aqueous solution and heat-denatured Col aqueous solution were mixed, followed by freeze-drying to obtain a spongy sheet. Cross-linkage between Col molecules was induced by UV irradiation to the spongy sheet (Type-I wound dressing). In a similar manner, a spongy sheet containing EGF (Type-II wound dressing) was prepared by freeze-drying the mixed solution of HMW-HA, LMW-HA and Col containing EGF. The efficacy of these products was evaluated in type-II diabetic BKS.Cg-+Lepr(db)/+Lepr(db) (db/db) mice. Wound dressings were applied to a full-thickness, dorsal skin defect measuring 1.5 cm × 2.0 cm, showing adipose tissue. In the control group, a commercially available artificial dermis composed of collagen spongy sheet (TERUDERMIS(®)) was used. A commercially available polyurethane film dressing (Bioclusive(®)) was applied over each wound dressing. After 1 week of application, wound conditions were evaluated based on their gross and histological appearances. Type-I and -II wound dressings promoted a decrease in wound size associated with angiogenesis and granulation tissue formation, compared with the artificial dermis. In particular, Type-II wound dressings promoted sufficient re-epithelialization. These findings indicate that the combination of HA, Col and EGF promotes wound healing by stimulating cell activity including cell migration and proliferation on the adipose tissue in a diabetic wound. Type-I and -II wound dressings would be useful to prepare a well-vascularized wound bed acceptable for split-thickness auto-skin grafting.

  18. Protease Inhibition by Oleic Acid Transfer From Chronic Wound Dressings to Albumin

    SciTech Connect

    Edwards, J. V.; Howley, Phyllis; Davis, Rachel M.; Mashchak, Andrew D.; Goheen, Steven C.

    2007-08-01

    High elastase and cathepsin G activities have been observed in chronic wounds. These levels can inhibit healing through degradation of growth factors, cytokines, and extracellular matrix proteins. Oleic acid (18:1) is a non-toxic elastase inhibitor with some potential for redressing the imbalance of elastase activity found in chronic wounds. Cotton wound dressing material was characterized as a transfer carrier for affinity uptake of 18:1 by albumin under conditions mimicking chronic wounds. 18:1-treated cotton was examined for its ability to bind and release the fatty acid in the presence of albumin. The mechanism of 18:1 uptake from cotton and binding by albumin was examined with both intact dressings and cotton fiber-designed chromatography. Raman spectra of the albumin-18:1 complexes under liquid-liquid equilibrium conditions revealed fully saturated albumin-18:1 complexes with a 1:1 weight ratio of albumin:18:1. Cotton chromatography under liquid-solid equilibrium conditions revealed oleic acid transfer from cotton to albumin at 27 mole equivalents of 18:1 per mole albumin. Cotton was contrasted with hydrogel, and hydrocolloid wound dressing for its comparative ability to lower elastase activity. Each dressing material evaluated was found to release 18:1 in the presence of albumin with significant inhibition of elastase activity. The 18:1-formulated wound dressings lowered elastase activity in a dose dependent manner in the order cotton gauze > hydrogel > hydrocolloid. In contrast the cationic serine protease Cathepsin G was inihibited by 18:1 within a narrow range of 18:1-cotton formulations. Four per cent Albumin solutions were most effective in binding cotton bound-18:1. However, 2% albumin was sufficient to transfer quantities of 18:1 necessary to achieve a significant elastase-lowering effect. Formulations with 128 mg 18:1/g cotton gauze had equivalent elastase lowering with 1 - 4% albumin. 18:1 bound to cotton wound dressings may have promise in the

  19. Viability of murine norovirus in salads and dressings and its inactivation using heat-denatured lysozyme.

    PubMed

    Takahashi, Hajime; Tsuchiya, Tomoki; Takahashi, Michiko; Nakazawa, Moemi; Watanabe, Tomoka; Takeuchi, Akira; Kuda, Takashi; Kimura, Bon

    2016-09-16

    In recent years, a number of food poisoning outbreaks due to the contamination of norovirus in ready-to-eat (RTE) foods such as salads have been reported, and this issue is regarded as a global problem. The risk of contamination of fresh vegetables with norovirus has been previously reported, but the survivability of norovirus that contaminates salads remains unknown. In addition, there have been limited reports on the control of norovirus in food products by using inactivating agents. In this study, the viability of norovirus in various types of salads and dressings was examined using murine norovirus strain 1 (MNV-1) as a surrogate for the closely related human norovirus. In addition, the inactivation of MNV-1 in salads was examined using heat-denatured lysozyme, which had been reported to inactivate norovirus. MNV-1 was inoculated in 4 types of salads (coleslaw, thousand island salad, vinaigrette salad, egg salad) and 3 types of dressings (mayonnaise, thousand island dressing, vinaigrette dressing), stored at 4°C for 5days. The results revealed that in the vinaigrette dressing, the infectivity of MNV-1 decreased by 2.6logPFU/mL in 5days, whereas in the other dressings and salads, the infectivity of MNV-1 did not show any significant decrease. Next, 1% heat-denatured lysozyme was added to the 4 types of salads, and subsequently it was found that in 2 types of salads (thousand island salad, vinaigrette salad), the infectivity of MNV-1 decreased by >4.0logPFU/g, whereas in coleslaw salad, a decrease of 3.0logPFU/g was shown. However, in egg salads, the infectivity of MNV-1 did not show such decrease. These results suggest that norovirus can survive for 5days in contaminated salads. Further, these findings also indicated that heat-denatured lysozyme had an inactivating effect on norovirus, even in salads. In the future, heat-denatured lysozyme can be used as a novel norovirus-inactivating agent, although it is essential to investigate the mechanism of inactivating

  20. Collaboration improves outcomes: cross county, joint acute and primary care, working party to select a super absorbent dressing.

    PubMed

    Fenwick, Kim; Florence, Lorraine; Godar, Sue; Guy, Heidi; Tilbe, Helen

    2012-11-01

    This abstract highlights the work undertaken by the Bedfordshire and Hertfordshire Tissue Viability Nurses Forum (BHTVNF) to select a super absorbent dressing for local formularies. A range of super absorbent dressings was selected to be included in the evaluation based on their accessibility via FP10 or NHS Supply chain. Dressings were evaluated in the hospital setting, community setting and leg ulcer clinics. Table top evaluations were also undertaken. Performance of dressings both clinically and via table top were considered along with costs. It was interesting to find out that hospital patients had different needs to community patients and as such three recommendations were made. The acute sector has added one super absorbent which is different from the community selected one. The community has also selected a lower performing super absorbent which the acute sector has not chosen.

  1. Comparison of a liquid and a powder insecticidal dressing to aid healing and prevent flystrike of mulesing wounds in lambs.

    PubMed

    Pearse, B H; Peucker, S K

    1991-05-01

    A proprietary insecticidal mulesing powder containing diazinon and an experimental liquid dressing based on eucalyptus oil, naphthalene, cresylic acid and chlorfenvinphos in a carrier of liquid hydrocarbons and petroleum oil were compared for their ability to promote wound healing and reduce the incidence of fly strike in freshly mulesed lambs. Throughout the trial period of 4 weeks, fly trapping confirmed the presence of Lucilia cuprina in the paddock where the ewes and lambs were grazing At inspection one month after mulesing, no deaths had occurred since mulesing and no lambs showed evidence of cutaneous myiasis, although a number of their dams (with 8 months wool) were struck. At 4 weeks after mulesing, the wounds of the lambs treated with the experimental liquid dressing showed better healing than those treated with the powder dressing. It was concluded that both mulesing preparations were effective in inhibiting flystrike, but the liquid dressing promoted faster wound healing than did the powder.

  2. Comparison of a liquid and a powder insecticidal dressing to aid healing and prevent flystrike of mulesing wounds in lambs.

    PubMed

    Pearse, B H; Peucker, S K

    1991-05-01

    A proprietary insecticidal mulesing powder containing diazinon and an experimental liquid dressing based on eucalyptus oil, naphthalene, cresylic acid and chlorfenvinphos in a carrier of liquid hydrocarbons and petroleum oil were compared for their ability to promote wound healing and reduce the incidence of fly strike in freshly mulesed lambs. Throughout the trial period of 4 weeks, fly trapping confirmed the presence of Lucilia cuprina in the paddock where the ewes and lambs were grazing At inspection one month after mulesing, no deaths had occurred since mulesing and no lambs showed evidence of cutaneous myiasis, although a number of their dams (with 8 months wool) were struck. At 4 weeks after mulesing, the wounds of the lambs treated with the experimental liquid dressing showed better healing than those treated with the powder dressing. It was concluded that both mulesing preparations were effective in inhibiting flystrike, but the liquid dressing promoted faster wound healing than did the powder. PMID:1883292

  3. Open-label clinical trial comparing the clinical and economic effectiveness of using a polyurethane film surgical dressing with gauze surgical dressings in the care of post-operative surgical wounds.

    PubMed

    Arroyo, Ana Abejón; Casanova, Pabló López; Soriano, José Verdú; Torra I Bou, Joan-Enric

    2015-06-01

    Surgical site infection (SSI) is a common postoperative complication and can cause avoidable morbidity and excessive costs for the health service. Novel dressings, designed specifically for postoperative wounds, can help to reduce the risk of SSI and other complications such as blistering. This study compared the use of a new polyurethane film surgical dressing (Opsite Post-Op Visible, Smith & Nephew, Hull, UK) with gauze and tape in the management of postoperative wounds. The results show that the polyurethane film dressing results in a significant reduction in SSI (1·4% versus 6·6%, P = 0·006) as well as a reduction in other postoperative wound complications (e.g. blistering and erythema). Economic analysis conducted alongside the study suggests that these improved outcomes can be achieved at a lower treatment cost than gauze and tape dressings. The modest incremental cost of the polyurethane film surgical dressing is easily offset by the reduction in the costs related to treating SSI and other wound complications associated with gauze and tape dressings.

  4. In Vivo Performance of Chitosan/Soy-Based Membranes as Wound-Dressing Devices for Acute Skin Wounds

    PubMed Central

    Santos, Tírcia C.; Höring, Bernhard; Reise, Kathrin; Marques, Alexandra P.; Silva, Simone S.; Oliveira, Joaquim M.; Mano, João F.; Castro, António G.; van Griensven, Martijn

    2013-01-01

    Wound management represents a major clinical challenge on what concerns healing enhancement and pain control. The selection of an appropriate dressing plays an important role in both recovery and esthetic appearance of the regenerated tissue. Despite the wide range of available dressings, the progress in the wound care market relies on the increasing interest in using natural-based biomedical products. Herein, a rat wound-dressing model of partial-thickness skin wounds was used to study newly developed chitosan/soy (cht/soy)-based membranes as wound-dressing materials. Healing and repair of nondressed, cht/soy membrane-dressed, and Epigard®-dressed wounds were followed macroscopically and histologically for 1 and 2 weeks. cht/soy membranes performed better than the controls, promoting a faster wound repair. Re-epithelialization, observed 1 week after wounding, was followed by cornification of the outermost epidermal layer at the second week of dressing, indicating repair of the wounded tissue. The use of this rodent model, although in impaired healing conditions, may enclose some drawbacks regarding the inevitable wound contraction. Moreover, being the main purpose the evaluation of cht/soy-based membranes' performance in the absence of growth factors, the choice of a clinically relevant positive control was limited to a polymeric mesh, without any growth factor influencing skin healing/repair, Epigard. These new cht/soy membranes possess the desired features regarding healing/repair stimulation, ease of handling, and final esthetic appearance—thus, valuable properties for wound dressings. PMID:23083058

  5. Tegaderm CHG IV Securement Dressing for Central Venous and Arterial Catheter Insertion Sites: A NICE Medical Technology Guidance.

    PubMed

    Jenks, Michelle; Craig, Joyce; Green, William; Hewitt, Neil; Arber, Mick; Sims, Andrew

    2016-04-01

    Catheters are widely used for vascular access and for the administration of drugs or fluids in critically ill patients. This exposes patients to an infection risk. Tegaderm chlorhexidine gluconate (CHG) (developed by 3M)-a transparent securement dressing-covers and protects catheter sites and secures devices to the skin. It comprises a transparent adhesive dressing to act as a barrier against external contamination and an integrated gel pad containing an antiseptic agent. The Medical Technologies Advisory Committee (MTAC) at the National Institute for Health and Care Excellence (NICE) selected Tegaderm CHG for evaluation. One study was identified by the sponsor as relevant to the decision problem. From this, the sponsor concluded that compared with standard dressings, Tegaderm CHG is associated with lower rates of catheter-related infection, but increased dermatitis incidence. The External Assessment Centre (EAC) identified four paired comparative studies between Tegaderm CHG, other CHG dressings or standard dressings. The EAC agreed with the sponsor's conclusion, finding that CHG dressings reduce infections compared with standard dressings. The sponsor constructed a de novo costing model. Tegaderm CHG generated cost savings of £77.26 per patient compared with standard dressings and was cost saving in 98.5 % of a sample of sets of inputs (2013 prices). The EAC critiqued and updated the model's inputs, yielding similar results to those the sponsor estimate. The MTAC reviewed the evidence and decided to support the case for adoption, issuing a positive draft recommendation. After a public consultation, NICE published this as Medical Technology Guidance 25. PMID:26458938

  6. Prototype Development of the Intelligent Hydrogel Wound Dressing and Its Efficacy in the Detection of Model Pathogenic Wound Biofilms.

    PubMed

    Thet, N T; Alves, D R; Bean, J E; Booth, S; Nzakizwanayo, J; Young, A E R; Jones, B V; Jenkins, A Toby A

    2016-06-22

    The early detection of wound infection in situ can dramatically improve patient care pathways and clinical outcomes. There is increasing evidence that within an infected wound the main bacterial mode of living is a biofilm: a confluent community of adherent bacteria encased in an extracellular polymeric matrix. Here we have reported the development of a prototype wound dressing, which switches on a fluorescent color when in contact with pathogenic wound biofilms. The dressing is made of a hydrated agarose film in which the fluorescent dye containing vesicles were mixed with agarose and dispersed within the hydrogel matrix. The static and dynamic models of wound biofilms, from clinical strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis, were established on nanoporous polycarbonate membrane for 24, 48, and 72 h, and the dressing response to the biofilms on the prototype dressing evaluated. The dressing indicated a clear fluorescent/color response within 4 h, only observed when in contact with biofilms produced by a pathogenic strain. The sensitivity of the dressing to biofilms was dependent on the species and strain types of the bacterial pathogens involved, but a relatively higher response was observed in strains considered good biofilm formers. There was a clear difference in the levels of dressing response, when dressings were tested on bacteria grown in biofilm or in planktonic cultures, suggesting that the level of expression of virulence factors is different depending of the growth mode. Colorimetric detection on wound biofilms of prevalent pathogens (S. aureus, P. aeruginosa, and E. faecalis) is also demonstrated using an ex vivo porcine skin model of burn wound infection. PMID:26492095

  7. Prototype Development of the Intelligent Hydrogel Wound Dressing and Its Efficacy in the Detection of Model Pathogenic Wound Biofilms.

    PubMed

    Thet, N T; Alves, D R; Bean, J E; Booth, S; Nzakizwanayo, J; Young, A E R; Jones, B V; Jenkins, A Toby A

    2016-06-22

    The early detection of wound infection in situ can dramatically improve patient care pathways and clinical outcomes. There is increasing evidence that within an infected wound the main bacterial mode of living is a biofilm: a confluent community of adherent bacteria encased in an extracellular polymeric matrix. Here we have reported the development of a prototype wound dressing, which switches on a fluorescent color when in contact with pathogenic wound biofilms. The dressing is made of a hydrated agarose film in which the fluorescent dye containing vesicles were mixed with agarose and dispersed within the hydrogel matrix. The static and dynamic models of wound biofilms, from clinical strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis, were established on nanoporous polycarbonate membrane for 24, 48, and 72 h, and the dressing response to the biofilms on the prototype dressing evaluated. The dressing indicated a clear fluorescent/color response within 4 h, only observed when in contact with biofilms produced by a pathogenic strain. The sensitivity of the dressing to biofilms was dependent on the species and strain types of the bacterial pathogens involved, but a relatively higher response was observed in strains considered good biofilm formers. There was a clear difference in the levels of dressing response, when dressings were tested on bacteria grown in biofilm or in planktonic cultures, suggesting that the level of expression of virulence factors is different depending of the growth mode. Colorimetric detection on wound biofilms of prevalent pathogens (S. aureus, P. aeruginosa, and E. faecalis) is also demonstrated using an ex vivo porcine skin model of burn wound infection.

  8. Fabrication, characterization, and in vitro evaluation of silver-containing arabinoxylan foams as antimicrobial wound dressing.

    PubMed

    Aduba, Donald C; An, Seon-Sook; Selders, Gretchen S; Wang, Juan; Andrew Yeudall, W; Bowlin, Gary L; Kitten, Todd; Yang, Hu

    2016-10-01

    Arabinoxylan ferulate (AXF) foams were fabricated via enzymatic peroxidase/hydrogen peroxide crosslinking reaction followed by freeze-drying and studied as a potential wound dressing material. The AXF foam's rheological, morphological, porous, and swelling properties were examined. AXF foams were found to be a viscoelastic material that proved to be highly porous and water absorbent. AXF foams possessed low endotoxin levels and were cytocompatible with fibroblasts. Silver was successfully integrated into AXF foams and slowly released over 48 h. AXF foams impregnated with silver demonstrated efficacy inhibiting bacterial growth according to a modified Kirby-Bauer disk diffusion susceptibility test. Overall, AXF foams possess appropriate material properties and the silver-loaded AXF foams showed antimicrobial activity necessary to be a candidate material in wound dressing development. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 2456-2465, 2016. PMID:27199211

  9. Relativistic electronic dressing in laser-assisted ionization of atomic hydrogen by electron impact

    SciTech Connect

    Attaourti, Y.; Taj, S.

    2004-06-01

    Within the framework of the coplanar binary geometry where it is justified to use plane wave solutions for the study of the (e,2e) reaction and in the presence of a circularly polarized laser field, we introduce as a first step the Dirac-Volkov plane wave Born approximation 1 where we take into account only the relativistic dressing of the incident and scattered electrons. Then, we introduce the Dirac-Volkov plane wave Born approximation 2 where we take totally into account the relativistic dressing of the incident, scattered, and ejected electrons. We then compare the corresponding triple differential cross sections for laser-assisted ionization of atomic hydrogen by electron impact both for the nonrelativistic and the relativistic regime.

  10. Atom-field dressed states in slow-light waveguide QED

    NASA Astrophysics Data System (ADS)

    Calajó, Giuseppe; Ciccarello, Francesco; Chang, Darrick; Rabl, Peter

    2016-03-01

    We discuss the properties of atom-photon bound states in waveguide QED systems consisting of single or multiple atoms coupled strongly to a finite-bandwidth photonic channel. Such bound states are formed by an atom and a localized photonic excitation and represent the continuum analog of the familiar dressed states in single-mode cavity QED. Here we present a detailed analysis of the linear and nonlinear spectral features associated with single- and multiphoton dressed states and show how the formation of bound states affects the waveguide-mediated dipole-dipole interactions between separated atoms. Our results provide both a qualitative and quantitative description of the essential strong-coupling processes in waveguide QED systems, which are currently being developed in the optical and microwave regimes.

  11. Phase diagram and spin mixing dynamics in spinor condensates with a microwave dressing field.

    PubMed

    Huang, Yixiao; Zhong, Wei; Sun, Zhe; Hu, Zheng-Da

    2015-01-01

    Spinor condensates immersed in a microwave dressing field, which access both negative and positive values of the net quadratic Zeeman effect, have been realized in a recent experiment. In this report, we study the ground state properties of a spinor condensate with a microwave dressing field which enables us to access both negative and positive values of quadratic Zeeman energy. The ground state exhibits three different phases by varying the magnetization and the net quadratic Zeeman energy for both cases of ferromagnetic and antiferromagnetic interactions. We investigate the atomic-number fluctuations of the ground state and show that the hyperfine state displays super-Poissonian and sub-Poissonian distributions in the different phases. We also discuss the dynamical properties and show that the separatrix has a remarkable relation to the magnetization. PMID:26403676

  12. Electrospun PCL membranes incorporated with biosynthesized silver nanoparticles as antibacterial wound dressings

    NASA Astrophysics Data System (ADS)

    Augustine, Robin; Kalarikkal, Nandakumar; Thomas, Sabu

    2016-03-01

    An open wound is highly prone to bacterial colonization and infection. Bacterial barrier property is an important factor that determines the success of a wound coverage material. Apart from the bacterial barrier property, presence of antibacterial agents can successfully eliminate the invasion and colonization of pathogen in the wound. Silver nanoparticles are well-known antimicrobial agents against a wide range of microorganisms. Biosynthesized silver nanoparticles are more acceptable for medical applications due to superior biocompatibility than chemically synthesized ones. Presence of biomolecules on biosynthesized silver nanoparticles enhances its therapeutic efficiency. Polycaprolactone (PCL) is a well-known material for biomedical applications including wound dressings. Electrospinning is an excellent technique for the fabrication of thin membranes for wound coverage applications with barrier property against microbes. In this paper, we report the fabrication and characterization of electrospun PCL membranes incorporated with biosynthesized silver nanoparticles for wound dressing applications.

  13. Development of clindamycin-loaded wound dressing with polyvinyl alcohol and sodium alginate.

    PubMed

    Kim, Jong Oh; Choi, Jun Young; Park, Jung Kil; Kim, Jeong Hoon; Jin, Sung Giu; Chang, Sun Woo; Li, Dong Xun; Hwang, Ma-Ro; Woo, Jong Soo; Kim, Jung-Ae; Lyoo, Won Seok; Yong, Chul Soon; Choi, Han-Gon

    2008-12-01

    To develop a clindamycin-loaded wound dressing, cross-linked hydrogel films were prepared using freeze-thawing method with various mixtures of polyvinyl alcohol (PVA) and sodium alginate (SA). The physicochemical properties such as swelling ratio, tensile strength and elongation of hydrogels were evaluated. The drug release from this clindamycin-loaded hydrogel, in vitro protein adsorption test and in vivo wound healing observations in rats were then performed. Increased SA concentration decreased the gelation %, maximum strength and break elongation, but it resulted into an increment in the swelling ability, elasticity and thermal stability of hydrogel film. However, SA had insignificant effect on the release of clindamycin. This hydrogel improved the healing rate of artificial wounds in rats. Thus, a clindamycin-loaded wound dressing with PVA and SA hydrogel should be a candidate for wound care.

  14. Quality assessment of the wound dressing procedure in patients at a university hospital.

    PubMed

    Nonino, Eleine Aparecida Penha Martins; Anselmi, Maria Luiza; Dalmas, José Carlos

    2008-01-01

    This observational and sectional study analyzed the quality of the wound dressing procedure performed on hospitalized patients at a medical surgical unit of a University Hospital, based on their classification according to the degree of care dependency and activity performance phases. Using a check list, 168 wound dressings were observed between October and December 2005. Procedure quality was analyzed based on the Positivity Index (IP) and values >70% were considered satisfactory. For the preparation, the IP was 68%, 63%, 73% and 75% for patients with degrees I, II, III and IV, respectively; for execution, 70%, 69%, 71% and 75% and, for unit organization, it was >70% for all degrees. However, the items: validity time frame checking, respect for aseptic principles and maintenance of logical sequence of procedures were compromised. Rigorous execution of procedures allows for risk decrease and assures beneficial results for patients, conferring quality to nursing actions.

  15. Preparation of chitosan/silk fibroin blending membrane fixed with alginate dialdehyde for wound dressing.

    PubMed

    Gu, Zhipeng; Xie, HuiXu; Huang, Chengcheng; Li, Li; Yu, Xixun

    2013-07-01

    The objective of this work was to prepare chitosan/silk fibroin (CS/SF) blending membranes crosslinked with alginate dialdehyde (ADA) as wound dressings and to evaluate the physical properties and biocompatibility of the membranes. The morphology of membrane was observed by scanning electron microscopy (SEM) which showed that the well consistency of these two compositions. Further, the stability, water absorption and water vapor permeability of the ADA fixed CS/SF membranes could meet the needs of wound dressing. Furthermore, the biocompatibility of ADA fixed membranes was investigated by MTT assays and SEM in vitro, and the membranes were found to promote the cell attachment and proliferation. These results suggest that ADA fixed CS/SF blending membranes with a suitable ratio could be a promising candidate for wound healing applications.

  16. Dressing-related pain in patients with chronic wounds: an international patient perspective.

    PubMed

    Price, Patricia E; Fagervik-Morton, Hilde; Mudge, Elizabeth J; Beele, Hilde; Ruiz, Jose Contreras; Nystrøm, Theis Huldt; Lindholm, Christina; Maume, Sylvie; Melby-Østergaard, Britta; Peter, Yolanda; Romanelli, Marco; Seppänen, Salla; Serena, Thomas E; Sibbald, Gary; Soriano, Jose Verdú; White, Wendy; Wollina, Uwe; Woo, Kevin Y; Wyndham-White, Carolyn; Harding, Keith G

    2008-06-01

    This cross-sectional international survey assessed patients' perceptions of their wound pain. A total of 2018 patients (57% female) from 15 different countries with a mean age of 68.6 years (SD = 15.4) participated. The wounds were categorised into ten different types with a mean wound duration of 19.6 months (SD = 51.8). For 2018 patients, 3361 dressings/compression systems were being used, with antimicrobials being reported most frequently (n= 605). Frequency of wound-related pain was reported as 32.2%, 'never' or 'rarely', 31.1%, 'quite often' and 36.6%, 'most' or 'all of the time', with venous and arterial ulcers associated with more frequent pain (P= 0.002). All patients reported that 'the wound itself' was the most painful location (n= 1840). When asked if they experienced dressing-related pain, 286 (14.7%) replied 'most of the time' and 334 (17.2%) reported pain 'all of the time'; venous, mixed and arterial ulcers were associated with more frequent pain at dressing change (P < 0.001). Eight hundred and twelve (40.2%) patients reported that it took <1 hour for the pain to subside after a dressing change, for 449 (22.2%) it took 1-2 hours, for 192 (9.5%) it took 3-5 hours and for 154 (7.6%) patients it took more than 5 hours. Pain intensity was measured using a visual analogue scale (VAS) (0-100) giving a mean score of 44.5 (SD = 30.5, n= 1981). Of the 1141 who reported that they generally took pain relief, 21% indicated that they did not feel it was effective. Patients were asked to rate six symptoms associated with living with a chronic wound; 'pain' was given the highest mean score of 3.1 (n= 1898). In terms of different types of daily activities, 'overdoing things' was associated with the highest mean score (mean = 2.6, n= 1916). During the stages of the dressing change procedure; 'touching/handling the wound' was given the highest mean score of 2.9, followed by cleansing and dressing removal (n= 1944). One thousand four hundred and eighty-five (80

  17. Dressed elliptic genus of heterotic compactifications with torsion and general bundles

    NASA Astrophysics Data System (ADS)

    Israël, Dan; Sarkis, Matthieu

    2016-08-01

    We define and compute the dressed elliptic genus of N=2 heterotic compactifications with torsion that are principal two-torus bundles over a K3 surface. We consider a large class of gauge bundles compatible with supersymmetry, consisting of a stable holomorphic vector bundle over the base together with an Abelian bundle over the total space, generalizing the computation previously done by the authors in the absence of the latter. Starting from a (0,2) gauged linear sigma-model with torsion we use supersymmetric localization to obtain the result. We provide also a mathematical definition of the dressed elliptic genus as a modified Euler characteristic and prove that both expressions agree for hypersurfaces in weighted projective spaces. Finally we show that it admits a natural decomposition in terms of N=4 superconformal characters, that may be useful to investigate moonshine phenomena for this wide class of N=2 vacua, that includes K3 × T 2 compactifications as special cases.

  18. Synthesis and characterization of biosheet impregnated with Macrotyloma uniflorum extract for burn/wound dressings.

    PubMed

    Muthukumar, Thangavelu; Senthil, Rethinam; Sastry, Thotapalli Parvathaleswara

    2013-02-01

    Developing biomaterials having wound healing properties within the search of a common man is the need of hour, particularly in developing and third world countries. Keeping this objective in view we have developed a wound dressing material, in sheet form, containing fish scale collagen (FSC) and physiologically clotted fibrin (PCF), both are by products of aqua food and meat industries respectively. To impart antimicrobial properties to the composite sheet, it was incorporated with Macrotyloma uniflorum plant extract (MPE). SEM pictures have shown that FSC:PCF:MPE composite has fibrous and porous surface which helps in transportation of oxygen as well as absorbing wound fluids and their evaporation. The biomaterials have shown 100% biocompatibility and the percentage cell viability was found to be above 89%. The FSC:PCF:MPE biocomposite film with required mechanical strength, biocompatibility and antimicrobial properties can be tried as a burn/wound dressing material.

  19. Antibacterial performance of polypropylene nonwoven fabric wound dressing surfaces containing passive and active components

    NASA Astrophysics Data System (ADS)

    Xin, Zhirong; Du, Shanshan; Zhao, Chunyu; Chen, Hao; Sun, Miao; Yan, Shunjie; Luan, Shifang; Yin, Jinghua

    2016-03-01

    A growing number of wound dressing-related nosocomial infections necessitate the development of novel antibacterial strategies. Herein, polypropylene non-woven fabric (PPNWF) was facilely modified with passive and active antibacterial components, namely photografting polymerization both N-Vinyl-2-pyrrolidone (NVP) and glycidyl methacrylate (GMA) monomers, and the introduction of guanidine polymer through the reaction between active amino groups and epoxy groups. The modified samples were confirmed by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), respectively. Water contact angle measurement, antibacterial test, platelet and red blood cell adhesion were used to evaluate the hydrophilicity, antibacterial properties and hemocompatibility of the samples. It was found that the antibacterial properties were obviously enhanced, meanwhile significantly suppressing platelet and red blood cell adhesion after the above modification. This PPNWF samples that possess antifouling and antimicrobial properties, have great potential in wound dressing applications.

  20. Dynamical Casimir–Polder force on a partially dressed atom in a cavity comprising a dielectric

    SciTech Connect

    Yang, H.; Zheng, T.Y. Zhang, X.; Shao, X.Q.; Pan, S.M.

    2014-05-15

    We put a two-level atom into a cavity comprising a dielectric with output coupling. An analytical expression of the dynamical Casimir–Polder force in such a system is obtained when the system starts from a partially dressed state. And the effects of several relevant parameters of the system on the time-dependent force are also discussed. -- Highlights: •We get the dynamical CP force on a partially dressed atom in a dielectric cavity. •The force in this cavity is larger than that in infinite dielectric space. •The force is not symmetric with respect to the center of the cavity. •The oscillating time of the force increases with the cavity size.