Science.gov

Sample records for 1 sexp 1

  1. A neutral hydrogen survey of the Hydra 1 cluster

    NASA Technical Reports Server (NTRS)

    Mcmahon, Pauline; Vangorkom, Jacqueline; Richter, Otto; Ferguson, Henry

    1993-01-01

    We are undertaking a project to image the entire volume of the Hydra 1 cluster of galaxies in neutral hydrogen using the VLA. This involves making a series of pointings spaced 30 min. (the half power beam width) apart, each observed at three velocity settings in order to span the whole velocity range of the cluster. The purpose of this survey is to determine the true distribution, both in space and velocity, of gas-rich systems and hence, to deduce what effects a dense environment may have on the evolution of these systems. Most surveys of clusters to date have been performed on optically selected samples. However, optically selected samples may provide misleading views of the distribution of gas-rich systems, since many low surface brightness galaxies have an abundance of neutral gas (Bothun et al. 1987, Giovanelli & Haynes 1989). The Hydra project is providing the first unbiased view of the HI distribution in a cluster of galaxies. Our 5 sigma sensitivity is 4.1 x 10(exp 7) solar M/beam, (assuming H(sub 0) = 75 km s(exp -1) Mpc(exp -1)) and our velocity resolution is 42 km s(exp -1). We have a spatial resolution of 45 sec., which means that only the largest galaxies are spatially resolved enough to determine HI disk size. Our coverage is about 50 percent of the central region plus eight other fields centered on bright spirals within about 2 deg. of the center.

  2. The mating-related loci sexM and sexP of the zygomycetous fungus Mucor mucedo and their transcriptional regulation by trisporoid pheromones.

    PubMed

    Wetzel, Jana; Burmester, Anke; Kolbe, Melanie; Wöstemeyer, Johannes

    2012-04-01

    The putative mating type locus of mucoralean fungi consists of a single high mobility group (HMG)-domain transcription factor gene, sexM or sexP, flanked by genes for an RNA helicase and a triosephosphate transporter. We used degenerate primers derived from the amino acid sequence of the RNA helicase to sequence a fragment of this gene from Mucor mucedo. This fragment was extended by inverse PCR to obtain the complete sequences of the sex loci from both mating types of M. mucedo. The sex loci in M. mucedo reflect the general picture obtained previously for Phycomyces blakesleeanus, presenting a single HMG-domain transcription factor gene, sexM and sexP in the minus and plus mating types, respectively. These are located next to a gene for RNA helicase. Transcriptional analysis by quantitative real-time PCR showed that only transcription of sexM is considerably stimulated by adding trisporoid pheromones, thus mimicking sexual stimulation, whereas sexP is only slightly affected. These differences in regulation between sexM and sexP are supported by the observation that the promoter sequences controlling these genes show no similarities. The protein structures themselves are considerably different. The SexM, but not the SexP protein harbours a nuclear localization sequence. The SexM protein is indeed transported to nuclei. This was shown by means of a GFP fusion construct that was used to study the localization of SexM in the yeast Saccharomyces cerevisiae. The fusion protein is highly enriched in nuclei.

  3. 1,1,1-Trichloroethane

    Integrated Risk Information System (IRIS)

    EPA / 635 / R - 03 / 013 www.epa.gov / iris TOXICOLOGICAL REVIEW OF 1,1,1 - TRICHLOROETHANE ( CAS No . 71 - 55 - 6 ) In Support of Summary Information on the Integrated Risk Information System ( IRIS ) August 2007 U.S . Environmental Protection Agency Washington , DC DISCLAIMER This document has bee

  4. MI1AENG1

    Atmospheric Science Data Center

    2014-09-03

    MI1AENG1 MISR Level 1A Engineering Data File Type 1: Reformatted Annotated Level 1A product for the camera engineering data, which represents indicators of sampled measurements. ... Status Production Report Read Software Files :  Data Product Specification Versioning ...

  5. SSCA1-K1

    SciTech Connect

    Baker, Matthew

    2015-11-06

    SSCA1-K1 is a parallel implementation of kernel 1 of the SSCA1 benchmark suite released by the DARPA HPCS program. This kernel is able to run in parallel on a distributed shared memory system at extreme scales using OpenSHMEM.

  6. Far Ultraviolet Spectroscopic Explorer Observations of the Seyfert 1.5 Galaxy NGC 5548 in a Low State

    NASA Technical Reports Server (NTRS)

    Brotherton, M. S.; Green, R. F.; Kriss, G. A.; Oegerle, W.; Kaiser, M. E.; Zheng, W.; Hutchings, J. B.; Fisher, Richard R. (Technical Monitor)

    2001-01-01

    We present far-ultraviolet spectra of the Seyfert 1.5 galaxy NGC 5548 obtained in 2000 June with the Far Ultraviolet Spectroscopic Explorer (FUSE). Our data span the observed wavelength range 915-1185 A at a resolution of approximately 20 km s(exp -1). The spectrum shows a weak continuum and emission from O VI (lambda)(lambda)1032, 1038, C III (lambda)977, and He II (lambda)1085. The FUSE data were obtained when the AGN (Active Galactic Nuclei) was in a low state, which has revealed strong, narrow O VI emission lines. We also resolve intrinsic, associated absorption lines of O VI and the Lyman series. Several distinct kinematic components are present, spanning a velocity range of approximately 0 to -1300 km s(exp -1) relative to systemic, with kinematic structure similar to that seen in previous observations of longer wavelength ultraviolet (UV) lines. We explore the relationships between the far-UV (ultraviolet) absorbers and those seen previously in the UV and X-rays. We find that the high-velocity UV absorption component is consistent with being low-ionization, contrary to some previous claims, and is consistent with its non-detection in high-resolution X-ray spectra. The intermediate velocity absorbers, at -300 to -400 km s(exp -1), show H I and O VI column densities consistent with having contributions from both a high-ionization X-ray absorber and a low-ionization UV absorber. No single far-UV absorbing component can be solely identified with the X-ray absorber.

  7. 1,1-Carboboration.

    PubMed

    Kehr, Gerald; Erker, Gerhard

    2012-02-11

    The use of very electrophilic boranes RB(C(6)F(5))(2) widens the scope of the 1,1-carboboration reaction substantially. Simple terminal alkynes HC≡CR undergo this reaction with the RB(C(6)F(5))(2) reagents rapidly under mild conditions to give high yields of very useful new alkenylborane products. Even internal alkynes RC≡CR undergo 1,1-carboboration with the RB(C(6)F(5))(2) reagents to provide a novel way of carbon-carbon σ-bond activation. Variants of these reactions involving phosphorus substituted alkynes and more complex bisalkynyl main group and transition metal substrates give rise to the formation of very interesting functionalized metallacyclic products upon treatment with RB(C(6)F(5))(2) reagents by means of reaction sequences involving selective 1,1-carboboration steps. PMID:22116402

  8. 1,1-Difluoroethane

    Integrated Risk Information System (IRIS)

    1,1 - Difluoroethane ; CASRN 75 - 37 - 6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogen

  9. 1,1-Dichloroethane

    Integrated Risk Information System (IRIS)

    1,1 - Dichloroethane ; CASRN 75 - 34 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogen

  10. 1 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Definitions. 1.1 Section 1.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL DEFINITIONS § 1.1 Definitions. As used in this chapter, unless the context requires otherwise— Administrative Committee means the Administrative Committee of...

  11. 1 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Definitions. 1.1 Section 1.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL DEFINITIONS § 1.1 Definitions. As used in this chapter, unless the context requires otherwise— Administrative Committee means the Administrative Committee of...

  12. 1 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Definitions. 1.1 Section 1.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL DEFINITIONS § 1.1 Definitions. As used in this chapter, unless the context requires otherwise— Administrative Committee means the Administrative Committee of...

  13. 1 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Definitions. 1.1 Section 1.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL DEFINITIONS § 1.1 Definitions. As used in this chapter, unless the context requires otherwise— Administrative Committee means the Administrative Committee of...

  14. 1 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Definitions. 1.1 Section 1.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL DEFINITIONS § 1.1 Definitions. As used in this chapter, unless the context requires otherwise— Administrative Committee means the Administrative Committee of...

  15. An X-ray Investigation of the NGC 346 Field. 1; The LBV HD 5980 and the NGC 346 Cluster

    NASA Technical Reports Server (NTRS)

    Naze, Y.; Hartwell, J. M.; Stevens, I. R.; Corcoran, M. F.; Chu, Y.-H.; Koenigsberger, G.; Moffat, A. F. J.; Niemela, V. S.

    2002-01-01

    We present results from a Chandra observation of the NGC 346 star formation region, which contains numerous massive stars, and is related to N66, the largest H(II) region of the SMC (Small Magellanic Cloud). In this first paper, we will focus on the characteristics of the main objects of the field. The NGC 346 cluster itself shows only relatively faint X-ray emission (with L((sub X)(sup unabs)) is approximately 1.5 x 10(exp 34) erg s(exp -1), tightly correlated with the core of the cluster. In the field also lies HD 5980, a LBV (Luminous Blue Variable) star in a binary (or triple system) that is detected for the first time at X-ray energies. The star is X-ray bright, with an unabsorbed luminosity of L((sub X)(sup unabs)) is approximately 1.7 x 10(exp 34) erg s(exp -1), but needs to be monitored further to investigate its X-ray variability over a complete orbital cycle. The high X-ray luminosity may be associated either with colliding winds in the binary system or with the 1994 eruption. HD 5980 is surrounded by a region of diffuse X-ray emission, which may be a superimposed supernova remnant.

  16. Thoughts on Why (-1)(-1) = +1

    ERIC Educational Resources Information Center

    Rapke, Tina

    2008-01-01

    This article considers why (-1)(-1) = +1 and how and why a teacher might go about explaining this concept to high school students without using pseudoreasoning. Furthermore, it provides a precise explanation, through the use of the distributive property, as to why (-1)(-1) = +1. (Contains 1 figure.)

  17. The Most Powerful Flaring Activity from the NLSy1 PMN J0948+0022

    NASA Technical Reports Server (NTRS)

    D'Ammando, F.; Orienti, M.; Finke, J.; Raiteri, C. M.; Hovatta, T.; Larsson, J.; Max-Moerbeck, W.; Perkins, J.; Readhead, A. C. S.; Richards, J. L.

    2014-01-01

    We report on multifrequency observations performed during 2012 December-2013 August of the first narrow-line Seyfert 1 galaxy detected in gamma rays, PMN J0948+0022 (z equal to 0.5846). A gamma-ray flare was observed by the Large Area Telescope on board Fermi during 2012 December-2013 January, reaching a daily peak flux in the 0.1-100 GeV energy range of (155 plus or minus 31)×10(exp -8) ph cm (exp -2) s (exp -1) on 2013 January 1, corresponding to an apparent isotropic luminosity of approximately 1.5×10)exp 48) erg s(exp -1). The gamma-ray flaring period triggered Swift and VERITAS observations in addition to radio and optical monitoring by OVRO, MOJAVE, and CRTS. A strong flare was observed in optical, UV, and X- rays on 2012 December 30, quasi-simultaneously to the gamma-ray flare, reaching a record flux for this source from optical to gamma rays. VERITAS observations at very high energy (E greater than 100 GeV) during 2013 January 6-17 resulted in an upper limit of F(sub greater than 0.2 TeV) less than 4.0 × 10(exp -12) ph cm(exp -2) s(exp -1). We compared the spectral energy distribution (SED) of the flaring state in 2013 January with that of an intermediate state observed in 2011. The two SEDs, modelled as synchrotron emission and an external Compton scattering of seed photons from a dust torus, can be modelled by changing both the electron distribution parameters and the magnetic field.

  18. 1-Chloro-1,1-difluoroethane

    Integrated Risk Information System (IRIS)

    1 - Chloro - 1,1 - difluoroethane ; CASRN 75 - 68 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for

  19. 1,1,1,2-Tetrafluoroethane

    Integrated Risk Information System (IRIS)

    1,1,1,2 - Tetrafluoroethane ; CASRN 811 - 97 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Nonca

  20. 1,1,1,2-Tetrachloroethane

    Integrated Risk Information System (IRIS)

    1,1,1,2 - Tetrachloroethane ; CASRN 630 - 20 - 6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Nonca

  1. 1,1-Dichloroethylene (1,1-DCE)

    Integrated Risk Information System (IRIS)

    1,1 - Dichloroethylene ( 1,1 - DCE ) ; CASRN 75 - 35 - 4 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments f

  2. 1SXPS: A Deep Swift X-Ray Telescope Point Source Catalog with Light Curves and Spectra

    NASA Technical Reports Server (NTRS)

    Evans, P. A.; Osborne, J. P.; Beardmore, A. P.; Page, K. L.; Willingale, R.; Mountford, C. J.; Pagani, C.; Burrows, D. N.; Kennea, J. A.; Perri, M.; Tagliaferri, G.; Gehrels, N.

    2013-01-01

    We present the 1SXPS (Swift-XRT point source) catalog of 151,524 X-ray point sources detected by the Swift-XRT in 8 yr of operation. The catalog covers 1905 sq deg distributed approximately uniformly on the sky. We analyze the data in two ways. First we consider all observations individually, for which we have a typical sensitivity of approximately 3 × 10(exp -13) erg cm(exp -2) s(exp -1) (0.3-10 keV). Then we co-add all data covering the same location on the sky: these images have a typical sensitivity of approximately 9 × 10(exp -14) erg cm(exp -2) s(exp -1) (0.3-10 keV). Our sky coverage is nearly 2.5 times that of 3XMM-DR4, although the catalog is a factor of approximately 1.5 less sensitive. The median position error is 5.5 (90% confidence), including systematics. Our source detection method improves on that used in previous X-ray Telescope (XRT) catalogs and we report greater than 68,000 new X-ray sources. The goals and observing strategy of the Swift satellite allow us to probe source variability on multiple timescales, and we find approximately 30,000 variable objects in our catalog. For every source we give positions, fluxes, time series (in four energy bands and two hardness ratios), estimates of the spectral properties, spectra and spectral fits for the brightest sources, and variability probabilities in multiple energy bands and timescales.

  3. Confirmation of a Radio-Selected Galaxy Overdensity at z=1.11

    NASA Technical Reports Server (NTRS)

    Stern, Daniel; Holden, Brad; Stanford, S. A.; Spinard, Hyron

    2003-01-01

    We report the discovery of a galaxy overdensity at z = 1.11 associated with the z = 1.110 high-redshift radio galaxy MG1 J04426+0202 (hereafter MG 0442+0202). The group, Cl 0442+0202, was found in a near-infrared survey of z > 1 radio galaxies undertaken to identify spatially coincident regions with a high density of objects red in I-K' color, typical of z > 1 elliptical galaxies. Spectroscopic observations from the Keck I telescope reveal five galaxies within 35" of MG 0442+0202 at 1.10 < z < 1.11. These member galaxies have broadband colors and optical spectra consistent with passively evolving elliptical galaxies formed at high redshift. Archival ROSAT observations reveal a 3 (sigma) detection of soft X-ray emission coincident with Cl 0442+0202 at a level 5 times greater than expected for the radio galaxy. These data suggest a rich galaxy cluster and inspired a 45 ks Chandra X-Ray Observatory observation. As expected, the radio galaxy is unresolved by Chandra but is responsible for approximately half the observed X-ray flux. The remaining ROSAT flux is resolved into four point sources within 15' of the radio galaxy, corresponding to a surface density 2 orders of magnitude higher than average for X-ray sources at these flux levels [S(0.5-2 keV) > 5 x 10(exp -16) ergs cm (exp -2) s(exp -1)]. One of these point sources is identified with a radio-quiet type II quasar at z = 1.863, akin to sources recently reported in deep Chandra surveys. The limit on an extended hot intracluster medium in the Chandra data is S(1-6 keV) < 1.9 x 10-15 ergs cm (exp -2) s(exp -1) (3 (sigma), 30" radius aperture). Though the X-ray observations do not confirm the existence of a massive bound cluster at z > 1, the success of the optical/near-infrared targeting of early-type systems near the radio galaxy validates searches using radio galaxies as beacons for high-redshift large-scale structure. We interpret Cl 0442+0202 as a massive cluster in the process of formation.

  4. Gbf1

    PubMed Central

    Claude, Alejandro; Zhao, Bao-Ping; Kuziemsky, Craig E.; Dahan, Sophie; Berger, Scott J.; Yan, Jian-Ping; Armold, Adrian D.; Sullivan, Eric M.; Melançon, Paul

    1999-01-01

    Expression cloning from a cDNA library prepared from a mutant CHO cell line with Golgi-specific resistance to Brefeldin A (BFA) identified a novel 206-kD protein with a Sec7 domain termed GBF1 for Golgi BFA resistance factor 1. Overexpression of GBF1 allowed transfected cells to maintain normal Golgi morphology and grow in the presence of BFA. Golgi- enriched membrane fractions from such transfected cells displayed normal levels of ADP ribosylation factors (ARFs) activation and coat protein recruitment that were, however, BFA resistant. Hexahistidine-tagged–GBF1 exhibited BFA-resistant guanine nucleotide exchange activity that appears specific towards ARF5 at physiological Mg2+concentration. Characterization of cDNAs recovered from the mutant and wild-type parental lines established that transcripts in these cells had identical sequence and, therefore, that GBF1 was naturally BFA resistant. GBF1 was primarily cytosolic but a significant pool colocalized to a perinuclear structure with the β-subunit of COPI. Immunogold labeling showed highest density of GBF1 over Golgi cisternae and significant labeling over pleiomorphic smooth vesiculotubular structures. The BFA-resistant nature of GBF1 suggests involvement in retrograde traffic. PMID:10402461

  5. Neurofibromatosis-1

    MedlinePlus

    ... family who have the same NF1 gene change. "Coffee-with-milk" ( cafe-au-lait ) spots are the ... Call your health care provider if: You notice coffee-with-milk colored spots on your child's skin ...

  6. GTM-1

    2007-02-08

    GTM-1 was developed for the assessment of radionuclide transport by the ground-water through geoligic formations whose properties can change along the pathway. The program was developed for specific use within Probabilistic System Assessment (PSA) Monte Carlo codes.

  7. 1,1,2-Trichloropropane

    Integrated Risk Information System (IRIS)

    1,1,2 - Trichloropropane ; CASRN 598 - 77 - 6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarci

  8. 1,1,2-Trichloroethane

    Integrated Risk Information System (IRIS)

    1,1,2 - Trichloroethane ; CASRN 79 - 00 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcino

  9. 26 CFR 1.1-1 - Income tax on individuals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Income tax on individuals. 1.1-1 Section 1.1-1... and Surtaxes § 1.1-1 Income tax on individuals. (a) General rule. (1) Section 1 of the Code imposes an... taxable years beginning before January 1, 1970) see section 3. The tax imposed is upon taxable......

  10. 26 CFR 1.1-1 - Income tax on individuals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Income tax on individuals. 1.1-1 Section 1.1-1... and Surtaxes § 1.1-1 Income tax on individuals. (a) General rule. (1) Section 1 of the Code imposes an... taxable years beginning before January 1, 1970) see section 3. The tax imposed is upon taxable......

  11. 1/N

    SciTech Connect

    Coleman, S.

    1980-03-01

    There exist families of field theories with symmetry group SO(N) (or SU(N)) that become simpler as N becomes larger. More precisely, the solutions to these theories possess an expansion in powers of 1/N. This expansion is the subject of these lectures. The 1/N expansion can be used to analyze model field theories. The 1/N expansion is developed for phi/sup 4/ theory and applied to two two-dimensional models with similar combinatoric structures, the Gross-Neveu model and the CP/sup N-1/ model. These models display (in the leading 1/N approximation) such interesting phenomena as asymptotic freedom, dynamical symmetry breaking, dimensional transmutation, and non-perturbative confinement. It is possible that the 1/N expansion, with N the number of colors, might fruitfully be applied to quantum chromodynamics. Unfortunately, it is not possible to make a decisive test of the approximation, because no one knows how to compute even the first term in the expansion in closed form. However, it is possible to argue that this first term, whatever its detailed form, has many properties that are also shared by the real world, and which are otherwise underived from field theory. These include the saturation of scattering amplitudes by an infinite number of narrow resonances, the essential feature of dual-resonance models. (RWR)

  12. TRPC1.

    PubMed

    Nesin, Vasyl; Tsiokas, Leonidas

    2014-01-01

    The TRPC1 ion channel was the first mammalian TRP channel to be cloned. In humans, it is encoded by the TRPC1 gene located in chromosome 3. The protein is predicted to consist of six transmembrane segments with the N- and C-termini located in the cytoplasm. The extracellular loop connecting transmembrane segments 5 and 6 participates in the formation of the ionic pore region. Inside the cell, TRPC1 is present in the endoplasmic reticulum, plasma membrane, intracellular vesicles, and primary cilium, an antenna-like sensory organelle functioning as a signaling platform. In human and rodent tissues, it shows an almost ubiquitous expression. TRPC1 interacts with a diverse group of proteins including ion channel subunits, receptors, and cytosolic proteins to mediate its effect on Ca(2+) signaling. It primarily functions as a cation nonselective channel within pathways controlling Ca(2+) entry in response to cell surface receptor activation. Through these pathways, it affects basic cell functions, such as proliferation and survival, differentiation, secretion, and cell migration, as well as cell type-specific functions such as chemotropic turning of neuronal growth cones and myoblast fusion. The biological role of TRPC1 has been studied in genetically engineered mice where the Trpc1 gene has been experimentally ablated. Although these mice live to adulthood, they show defects in several organs and tissues, such as the cardiovascular, central nervous, skeletal and muscular, and immune systems. Genetic and functional studies have implicated TRPC1 in diabetic nephropathy, Parkinson's disease, Huntington's disease, Duchenne muscular dystrophy, cancer, seizures, and Darier-White skin disease. PMID:24756701

  13. 26 CFR 1.1-1 - Income tax on individuals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Income tax on individuals. 1.1-1 Section 1.1-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Normal Taxes and Surtaxes § 1.1-1 Income tax on individuals. (a) General rule. (1) Section 1 of the Code imposes...

  14. 26 CFR 1.1-1 - Income tax on individuals.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 1 2013-04-01 2013-04-01 false Income tax on individuals. 1.1-1 Section 1.1-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Normal Taxes and Surtaxes § 1.1-1 Income tax on individuals. (a) General rule. (1) Section 1 of the Code imposes...

  15. 26 CFR 1.1-1 - Income tax on individuals.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 1 2012-04-01 2012-04-01 false Income tax on individuals. 1.1-1 Section 1.1-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX INCOME TAXES Normal Taxes and Surtaxes § 1.1-1 Income tax on individuals. (a) General rule. (1) Section 1 of the Code imposes...

  16. 1-Chlorobutane

    Integrated Risk Information System (IRIS)

    1 - Chlorobutane ; CASRN 109 - 69 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic

  17. Mystery #1

    Atmospheric Science Data Center

    2013-04-22

    ... is approximately 380 kilometers wide. Choose any reference material you like and see if you can answer these questions: 1.   This ... NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Science Mission Directorate, Washington, D.C. The Terra spacecraft is managed ...

  18. Maxie 1

    NASA Astrophysics Data System (ADS)

    Imhof, William L.; Voss, Henry D.; Chinn, Victor

    1987-12-01

    The satellite flight of the MAXIE-1 (Magnetospheric Atmospheric X-ray Imaging Experiment) instrument is being implemented under ONR (the Office of Naval Research) sponsorship. The MAXIE-1 instrument is being developed as a joint activity of Lockheed, the Aerospace Corporation, and the University of Bergen; much of the Lockheed development has been done under the Independent Research Program. Under ONR sponsorship that institution is responsible for managing the program, for providing spacecraft interface requirements, for providing interface activities undertaken in the last three months. Interactions have continued with co-investigators at the Aerospace Corp. and at the University of Bergen. NASTRAN model calculations, thermal analyses and an updated MAXIE assembly drawing and other drawings have been provided to RCA.

  19. SPITFIRE-1

    NASA Technical Reports Server (NTRS)

    Ryntz, Edward F.

    1995-01-01

    The purpose of this effort is to develop low-cost rapid forming superplastic aluminum that will be evaluated in pilot production trials for automotive SPF components. The alloy development study conducted under SPITFIRE-1 showed that the addition of CU or Mn to the base 5083 aluminum alloy refined the grain size, leading to enhanced superplastic properties. In SPITFIRE-2, these alloy variants will be further refined and studied to meet the target properties established earlier in the program. Mechanical properties, component forming and post-forming properties will be evaluated. Also, the alloy production process, including thermomechanical processing (TMP) optimization to reduce production cost, will be investigated during SPITFIRE-2. After identifying preferred compositions and production processing, the most promising alloy will be manufactured into production coils for verification during SPITFIRE-3. Components will be produced from these coils in SPITFIRE-4, and the process and component performance will be assessed.

  20. 26 CFR 1.7872-1-1.7872-4 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 13 2014-04-01 2014-04-01 false 1.7872-1-1.7872-4 Section 1.7872-1-1.7872-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) General Actuarial Valuations §§ 1.7872-11.7872-4...

  1. 26 CFR 1.7872-1-1.7872-4 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 13 2012-04-01 2012-04-01 false 1.7872-1-1.7872-4 Section 1.7872-1-1.7872-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) General Actuarial Valuations §§ 1.7872-11.7872-4...

  2. 26 CFR 1.7872-1-1.7872-4 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 13 2013-04-01 2013-04-01 false 1.7872-1-1.7872-4 Section 1.7872-1-1.7872-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) General Actuarial Valuations §§ 1.7872-11.7872-4...

  3. 26 CFR 1.7872-1-1.7872-4 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false 1.7872-1-1.7872-4 Section 1.7872-1-1.7872-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES General Actuarial Valuations §§ 1.7872-11.7872-4...

  4. 26 CFR 1.453-1-1.453-2 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false 1.453-1-1.453-2 Section 1.453-1-1.453-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Taxable Year for Which Items of Gross Income Included §§ 1.453-11.453-2...

  5. 26 CFR 1.7872-1-1.7872-4 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 13 2011-04-01 2011-04-01 false 1.7872-1-1.7872-4 Section 1.7872-1-1.7872-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) General Actuarial Valuations §§ 1.7872-11.7872-4...

  6. Methane dissociation on Pt(1 1 1), Ir(1 1 1) and PtIr(1 1 1) surface: A density functional theory study

    NASA Astrophysics Data System (ADS)

    Qi, Qiuhong; Wang, Xiujun; Chen, Li; Li, Baitao

    2013-11-01

    A periodic density functional theory (DFT) was utilized to calculate the dissociation process of methane (CH4) on Pt(1 1 1), Ir(1 1 1) and PtIr(1 1 1) surfaces. As compared to the adsorption energy, the most stable configurations of methane, methane dissociation species and co-adsorption of CHx (x = 0-3) with H were obtained. The kinetic results of the CH4 dissociation indicated that the dissociating of CH4 into CH3 and H is the rate-limiting step on the PtIr(1 1 1) and Ir(1 1 1) surfaces. CH was the most abundant species that was difficult to dehydrogenate into C and H. Particularly, the activation barrier for CH3 → CH2 + H and CH2 → CH + H on the Pt(1 1 1) surface is 3.5 and 1.4 times, respectively, higher than that on the PtIr(1 1 1) surface. According to the thermodynamics principles, the successive dehydrogenation of CH4 preferred to take place on the PtIr surface.

  7. Theoretical study of NH3 decomposition on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces: A comparison with clean Pd (1 1 1) and Cu (1 1 1)

    NASA Astrophysics Data System (ADS)

    Jiang, Zhao; Qin, Pei; Fang, Tao

    2016-05-01

    The adsorption and successive dehydrogenation mechanisms of NH3 on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces (the Pd atoms substitution of the first and second layers of Cu (1 1 1) surfaces) have been systematically investigated by density functional theory (DFT) method with a periodic slab model. All possible adsorption configurations of relevant intermediates on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces are identified. It is revealed that the adsorption configurations and corresponding adsorption energies of adsorbates are slightly changed on Pd-Cu (1 1 1) and Cu-Pd (1 1 1) surfaces. The adsorption energies of NHx(x = 0-3) species exhibit the following trend: NH3 < NH2 < NH < N. Then, the minimum energy path for the complete dehydrogenation of NH3 into adsorbed N and H is identified to explore the dehydrogenation mechanisms on different surfaces. The highest energy barrier and reaction energy on Pd-Cu (1 1 1) surface are greatly reduced to 1.56 and 0.99 eV, implying that the complete dehydrogenation of NH3 on Pd-Cu (1 1 1) surface is favorable both kinetically and thermodynamically, namely, the doped-Pd atoms in the first layer are the reaction active center. Compared to that on clean Pd (1 1 1) and Cu (1 1 1) surfaces, it is found that the synergistic effect exits in different layers of catalyst surfaces. The calculated results show that the layer-substituted Pd atoms on the surface of Cu catalysts exhibit a better catalytic activity for NH3 dehydrogenation compared to the clean Cu (1 1 1) surface.

  8. 26 CFR 1.453-1-1.453-2 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 6 2013-04-01 2013-04-01 false 1.453-1-1.453-2 Section 1.453-1-1.453-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Taxable Year for Which Items of Gross Income Included §§ 1.453-11.453-2...

  9. 26 CFR 1.453-1-1.453-2 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 6 2014-04-01 2014-04-01 false 1.453-1-1.453-2 Section 1.453-1-1.453-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Taxable Year for Which Items of Gross Income Included §§ 1.453-11.453-2...

  10. 26 CFR 1.453-1-1.453-2 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 6 2012-04-01 2012-04-01 false 1.453-1-1.453-2 Section 1.453-1-1.453-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Taxable Year for Which Items of Gross Income Included §§ 1.453-11.453-2...

  11. 26 CFR 1.453-1-1.453-2 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 6 2011-04-01 2011-04-01 false 1.453-1-1.453-2 Section 1.453-1-1.453-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Taxable Year for Which Items of Gross Income Included §§ 1.453-11.453-2...

  12. 31 CFR 1.1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false General. 1.1 Section 1.1 Money and... § 1.1 General. (a) Purpose and scope. (1) This subpart contains the regulations of the Department of... legal counsel to the components listed in paragraphs (a)(1)(i)(W), (a)(1)(i)(X), (a)(1)(i)(Y), and...

  13. 41 CFR 51-1.1 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Policy. 51-1.1 Section 51-1.1 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 1-GENERAL § 51-1.1 Policy. (a) It...

  14. 41 CFR 51-1.1 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Policy. 51-1.1 Section 51-1.1 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 1-GENERAL § 51-1.1 Policy. (a) It is...

  15. 41 CFR 51-1.1 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Policy. 51-1.1 Section 51-1.1 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 1-GENERAL § 51-1.1 Policy. (a) It is...

  16. 26 CFR 1.316-1 - Dividends.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... an example of the treatment of the distribution to Corporation P see paragraph (b)(2)(iii) of § 1.562... 26 Internal Revenue 4 2013-04-01 2013-04-01 false Dividends. 1.316-1 Section 1.316-1 Internal... TAXES (CONTINUED) Definitions; Constructive Ownership of Stock § 1.316-1 Dividends. (a)(1) The...

  17. 26 CFR 1.316-1 - Dividends.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... an example of the treatment of the distribution to Corporation P see paragraph (b)(2)(iii) of § 1.562... 26 Internal Revenue 4 2012-04-01 2012-04-01 false Dividends. 1.316-1 Section 1.316-1 Internal... TAXES (Continued) Definitions; Constructive Ownership of Stock § 1.316-1 Dividends. (a)(1) The...

  18. 24 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Purpose. 1.1 Section 1.1 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.1 Purpose. The purpose of this part 1 is to effectuate...

  19. 16 CFR 1.1 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Policy. 1.1 Section 1.1 Commercial Practices... Guidance Advisory Opinions § 1.1 Policy. (a) Any person, partnership, or corporation may request advice... Commission's views, where practicable, under the following circumstances. (1) The matter involves...

  20. 24 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Purpose. 1.1 Section 1.1 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.1 Purpose. The purpose of this part 1 is to effectuate...

  1. 16 CFR 1.1 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Policy. 1.1 Section 1.1 Commercial Practices... Guidance Advisory Opinions § 1.1 Policy. (a) Any person, partnership, or corporation may request advice... Commission's views, where practicable, under the following circumstances. (1) The matter involves...

  2. 21 CFR 1.1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false General. 1.1 Section 1.1 Food and Drugs FOOD AND... General Provisions § 1.1 General. (a) The provisions of regulations promulgated under the Federal Food... terms when used in regulations promulgated under that act. (c) The definition of package in § 1.20...

  3. 16 CFR 1.1 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Policy. 1.1 Section 1.1 Commercial Practices... Guidance Advisory Opinions § 1.1 Policy. (a) Any person, partnership, or corporation may request advice... Commission's views, where practicable, under the following circumstances. (1) The matter involves...

  4. 24 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Purpose. 1.1 Section 1.1 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.1 Purpose. The purpose of this part 1 is to effectuate...

  5. 41 CFR 51-1.1 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Policy. 51-1.1 Section 51-1.1 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 1-GENERAL § 51-1.1 Policy. (a) It is...

  6. 41 CFR 51-1.1 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Policy. 51-1.1 Section 51-1.1 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 1-GENERAL § 51-1.1 Policy. (a) It...

  7. Multifaceted [36]octaphyrin(1.1.1.1.1.1.1.1): deprotonation-induced switching among nonaromatic, Möbius aromatic, and Hückel antiaromatic species.

    PubMed

    Cha, Won-Young; Soya, Takanori; Tanaka, Takayuki; Mori, Hirotaka; Hong, Yongseok; Lee, Sangsu; Park, Kyu Hyung; Osuka, Atsuhiro; Kim, Dongho

    2016-05-01

    Deprotonation of nonaromatic octakis-(pentafluorophenyl)-substituted [36]octaphyrin(1.1.1.1.1.1.1.1) with tetrabutylammonium fluoride (TBAF) afforded monoanionic twisted Möbius aromatic species and dianinonic square Hückel antiaromatic species, depending upon the amount of TBAF. PMID:27067645

  8. 16 CFR 1.1 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Policy. 1.1 Section 1.1 Commercial Practices... Guidance Advisory Opinions § 1.1 Policy. (a) Any person, partnership, or corporation may request advice... Commission's views, where practicable, under the following circumstances. (1) The matter involves...

  9. 24 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Purpose. 1.1 Section 1.1 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.1 Purpose. The purpose of this part 1 is to effectuate...

  10. 8 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Definitions. 1.1 Section 1.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY GENERAL PROVISIONS DEFINITIONS § 1.1 Definitions. As used in this... Service means the Immigration and Naturalization Service, as it existed prior to March 1, 2003....

  11. 24 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Purpose. 1.1 Section 1.1 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.1 Purpose. The purpose of this part 1 is to effectuate...

  12. 16 CFR 1.1 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Policy. 1.1 Section 1.1 Commercial Practices... Guidance Advisory Opinions § 1.1 Policy. (a) Any person, partnership, or corporation may request advice... Commission's views, where practicable, under the following circumstances. (1) The matter involves...

  13. 43 CFR 1784.1-1 - Establishment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Establishment. 1784.1-1 Section 1784.1-1..., DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) COOPERATIVE RELATIONS Advisory Committees § 1784.1-1... Secretary has— (1) Determined as a matter of formal record, after consultation with the General...

  14. 43 CFR 2563.1-1 - Application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Application. 2563.1-1 Section 2563.1-1... § 2563.1-1 Application. (a) Form and contents of applications. Applications under the Act of March 3... facts: (1) The age and citizenship of applicant. (2) The actual use and occupancy of the land for...

  15. 43 CFR 2563.1-1 - Application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Application. 2563.1-1 Section 2563.1-1... § 2563.1-1 Application. (a) Form and contents of applications. Applications under the Act of March 3... facts: (1) The age and citizenship of applicant. (2) The actual use and occupancy of the land for...

  16. 43 CFR 1784.1-1 - Establishment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Establishment. 1784.1-1 Section 1784.1-1..., DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) COOPERATIVE RELATIONS Advisory Committees § 1784.1-1... Secretary has— (1) Determined as a matter of formal record, after consultation with the General...

  17. 43 CFR 9180.1-1 - Meridians.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Meridians. 9180.1-1 Section 9180.1-1..., DEPARTMENT OF THE INTERIOR TECHNICAL SERVICES (9000) CADASTRAL SURVEY Cadastral Surveys; General § 9180.1-1... production, in accordance with section 1 of the Act of August 24, 1912 (37 Stat. 497), as amended (5...

  18. 26 CFR 2.1-1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Definitions. 2.1-1 Section 2.1-1 Internal... CONSTRUCTION RESERVE FUND § 2.1-1 Definitions. (a) As used in the regulations in this part, except as otherwise expressly provided— (1) Act means the Merchant Marine Act, 1936, as amended (46 U.S.C. 27). (2)...

  19. 43 CFR 2563.1-1 - Application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Application. 2563.1-1 Section 2563.1-1... § 2563.1-1 Application. (a) Form and contents of applications. Applications under the Act of March 3... facts: (1) The age and citizenship of applicant. (2) The actual use and occupancy of the land for...

  20. 43 CFR 1784.1-1 - Establishment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Establishment. 1784.1-1 Section 1784.1-1..., DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) COOPERATIVE RELATIONS Advisory Committees § 1784.1-1... Secretary has— (1) Determined as a matter of formal record, after consultation with the General...

  1. 15 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Purpose. 1.1 Section 1.1 Commerce and Foreign Trade Office of the Secretary of Commerce THE SEAL OF THE DEPARTMENT OF COMMERCE § 1.1 Purpose. The purpose of this part is to describe the seal of the Department of Commerce and to...

  2. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  3. 17 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1...

  4. 25 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false 1.1 Section 1.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROCEDURES AND PRACTICE APPLICABILITY OF RULES OF THE BUREAU OF INDIAN AFFAIRS § 1.1...

  5. 36 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Purpose. 1.1 Section 1.1 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS § 1.1 Purpose. (a) The regulations in this chapter provide for the proper use, management,...

  6. 27 CFR 1.1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false General. 1.1 Section 1.1 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE... OF DISTILLED SPIRITS AND WINE, BULK SALES AND BOTTLING OF DISTILLED SPIRITS Scope § 1.1 General....

  7. 8 CFR 1.1 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Applicability. 1.1 Section 1.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY GENERAL PROVISIONS DEFINITIONS § 1.1 Applicability. This part further defines some of the terms already described in section 101 and other sections of the...

  8. 30 CFR 1.1 - Official emblem.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Official emblem. 1.1 Section 1.1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OFFICIAL EMBLEM AND OMB CONTROL NUMBERS... OFFICIAL EMBLEM § 1.1 Official emblem. The following emblem is established and shall be used as...

  9. 17 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1...

  10. 17 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1...

  11. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  12. 15 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Purpose. 1.1 Section 1.1 Commerce and Foreign Trade Office of the Secretary of Commerce THE SEAL OF THE DEPARTMENT OF COMMERCE § 1.1 Purpose. The purpose of this part is to describe the seal of the Department of Commerce and to...

  13. 8 CFR 1.1 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Applicability. 1.1 Section 1.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY GENERAL PROVISIONS DEFINITIONS § 1.1 Applicability. This part further defines some of the terms already described in section 101 and other sections of the...

  14. 43 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Purpose. 1.1 Section 1.1 Public Lands: Interior Office of the Secretary of the Interior PRACTICES BEFORE THE DEPARTMENT OF THE INTERIOR § 1.1 Purpose. This part governs the participation of individuals in proceedings, both formal and informal,...

  15. 25 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false 1.1 Section 1.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROCEDURES AND PRACTICE APPLICABILITY OF RULES OF THE BUREAU OF INDIAN AFFAIRS § 1.1...

  16. 43 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Purpose. 1.1 Section 1.1 Public Lands: Interior Office of the Secretary of the Interior PRACTICES BEFORE THE DEPARTMENT OF THE INTERIOR § 1.1 Purpose. This part governs the participation of individuals in proceedings, both formal and informal,...

  17. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  18. 15 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Purpose. 1.1 Section 1.1 Commerce and Foreign Trade Office of the Secretary of Commerce THE SEAL OF THE DEPARTMENT OF COMMERCE § 1.1 Purpose. The purpose of this part is to describe the seal of the Department of Commerce and to...

  19. 8 CFR 1.1 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Applicability. 1.1 Section 1.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY GENERAL PROVISIONS DEFINITIONS § 1.1 Applicability. This part further defines some of the terms already described in section 101 and other sections of the...

  20. 30 CFR 1.1 - Official emblem.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Official emblem. 1.1 Section 1.1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OFFICIAL EMBLEM AND OMB CONTROL NUMBERS... OFFICIAL EMBLEM § 1.1 Official emblem. The following emblem is established and shall be used as...

  1. 49 CFR 1.1 - Overview.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Overview. 1.1 Section 1.1 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF POWERS AND DUTIES General § 1.1 Overview. This part describes the organization of the United States Department of Transportation...

  2. 25 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true 1.1 Section 1.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROCEDURES AND PRACTICE APPLICABILITY OF RULES OF THE BUREAU OF INDIAN AFFAIRS § 1.1...

  3. 30 CFR 1.1 - Official emblem.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Official emblem. 1.1 Section 1.1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OFFICIAL EMBLEM AND OMB CONTROL NUMBERS... OFFICIAL EMBLEM § 1.1 Official emblem. The following emblem is established and shall be used as...

  4. 27 CFR 1.1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false General. 1.1 Section 1.1 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE... OF DISTILLED SPIRITS AND WINE, BULK SALES AND BOTTLING OF DISTILLED SPIRITS Scope § 1.1 General....

  5. 49 CFR 1.1 - Overview.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Overview. 1.1 Section 1.1 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF POWERS AND DUTIES General § 1.1 Overview. This part describes the organization of the United States Department of Transportation...

  6. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  7. 43 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Purpose. 1.1 Section 1.1 Public Lands: Interior Office of the Secretary of the Interior PRACTICES BEFORE THE DEPARTMENT OF THE INTERIOR § 1.1 Purpose. This part governs the participation of individuals in proceedings, both formal and informal,...

  8. 36 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Purpose. 1.1 Section 1.1 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS § 1.1 Purpose. (a) The regulations in this chapter provide for the proper use, management,...

  9. 27 CFR 1.1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false General. 1.1 Section 1.1 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE... OF DISTILLED SPIRITS AND WINE, BULK SALES AND BOTTLING OF DISTILLED SPIRITS Scope § 1.1 General....

  10. 49 CFR 1.1 - Overview.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Overview. 1.1 Section 1.1 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF POWERS AND DUTIES General § 1.1 Overview. This part describes the organization of the United States Department of Transportation...

  11. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  12. 36 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Purpose. 1.1 Section 1.1 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS § 1.1 Purpose. (a) The regulations in this chapter provide for the proper use, management,...

  13. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  14. 43 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Purpose. 1.1 Section 1.1 Public Lands: Interior Office of the Secretary of the Interior PRACTICES BEFORE THE DEPARTMENT OF THE INTERIOR § 1.1 Purpose. This part governs the participation of individuals in proceedings, both formal and informal,...

  15. 36 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Purpose. 1.1 Section 1.1 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS § 1.1 Purpose. (a) The regulations in this chapter provide for the proper use, management,...

  16. 15 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Purpose. 1.1 Section 1.1 Commerce and Foreign Trade Office of the Secretary of Commerce THE SEAL OF THE DEPARTMENT OF COMMERCE § 1.1 Purpose. The purpose of this part is to describe the seal of the Department of Commerce and to...

  17. 44 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... implementation of paragraph (a) is contained in 44 CFR part 5, subpart B. (c) This part contains policies and... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Purpose. 1.1 Section 1.1... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.1 Purpose. (a) This part contains the basic...

  18. 8 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Definitions. 1.1 Section 1.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY GENERAL PROVISIONS DEFINITIONS § 1.1 Definitions. As used in this...) The term Service means the Immigration and Naturalization Service, as it existed prior to March...

  19. 36 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Purpose. 1.1 Section 1.1 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS § 1.1 Purpose. (a) The regulations in this chapter provide for the proper use, management,...

  20. 27 CFR 1.1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false General. 1.1 Section 1.1 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE... OF DISTILLED SPIRITS AND WINE, BULK SALES AND BOTTLING OF DISTILLED SPIRITS Scope § 1.1 General....

  1. 27 CFR 1.1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false General. 1.1 Section 1.1 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE... OF DISTILLED SPIRITS AND WINE, BULK SALES AND BOTTLING OF DISTILLED SPIRITS Scope § 1.1 General....

  2. 30 CFR 1.1 - Official emblem.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Official emblem. 1.1 Section 1.1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OFFICIAL EMBLEM AND OMB CONTROL NUMBERS... OFFICIAL EMBLEM § 1.1 Official emblem. The following emblem is established and shall be used as...

  3. 17 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1...

  4. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  5. 30 CFR 1.1 - Official emblem.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Official emblem. 1.1 Section 1.1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OFFICIAL EMBLEM AND OMB CONTROL NUMBERS... OFFICIAL EMBLEM § 1.1 Official emblem. The following emblem is established and shall be used as...

  6. 43 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Purpose. 1.1 Section 1.1 Public Lands: Interior Office of the Secretary of the Interior PRACTICES BEFORE THE DEPARTMENT OF THE INTERIOR § 1.1 Purpose. This part governs the participation of individuals in proceedings, both formal and informal,...

  7. 15 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Purpose. 1.1 Section 1.1 Commerce and Foreign Trade Office of the Secretary of Commerce THE SEAL OF THE DEPARTMENT OF COMMERCE § 1.1 Purpose. The purpose of this part is to describe the seal of the Department of Commerce and to...

  8. 49 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Purpose. 1.1 Section 1.1 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF POWERS AND DUTIES General § 1.1 Purpose. This part describes the organization of the Department of Transportation and provides for...

  9. 49 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Purpose. 1.1 Section 1.1 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF POWERS AND DUTIES General § 1.1 Purpose. This part describes the organization of the Department of Transportation and provides for...

  10. 23 CFR 1.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Purpose. 1.1 Section 1.1 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GENERAL MANAGEMENT AND ADMINISTRATION GENERAL § 1.1 Purpose. The purpose of the regulations in this part is to implement and carry out the provisions of Federal...

  11. 25 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false 1.1 Section 1.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROCEDURES AND PRACTICE APPLICABILITY OF RULES OF THE BUREAU OF INDIAN AFFAIRS § 1.1...

  12. 25 CFR 1.1 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false 1.1 Section 1.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROCEDURES AND PRACTICE APPLICABILITY OF RULES OF THE BUREAU OF INDIAN AFFAIRS § 1.1...

  13. 21 CFR 1.1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false General. 1.1 Section 1.1 Food and Drugs FOOD AND... General Provisions § 1.1 General. (a) The provisions of regulations promulgated under the Federal Food... in §§ 101.1, 201.60, 501.1, 701.10 and 801.60 of this chapter; and the requirements pertaining...

  14. 18 CFR 1b.1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 1b.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.1 Definitions. For purposes of this part— (a... pipelines, electric utilities and hydroelectric projects....

  15. 18 CFR 1b.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 1b.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.1 Definitions. For purposes of this part— (a... pipelines, electric utilities and hydroelectric projects....

  16. 18 CFR 1b.1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 1b.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.1 Definitions. For purposes of this part— (a... pipelines, electric utilities and hydroelectric projects....

  17. 18 CFR 1b.1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 1b.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.1 Definitions. For purposes of this part— (a... pipelines, electric utilities and hydroelectric projects....

  18. 18 CFR 1b.1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 1b.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.1 Definitions. For purposes of this part— (a... pipelines, electric utilities and hydroelectric projects....

  19. Metabolism of 1-fluoro-1,1,2-trichloroethane, 1,2-dichloro-1,1-difluoroethane, and 1,1,1-trifluoro-2-chloroethane.

    PubMed

    Yin, H; Jones, J P; Anders, M W

    1995-03-01

    1-Fluoro-1,1,2-trichloroethane (HCFC-131a), 1,2-dichloro-1,1-difluoroethane (HCFC-132b), and 1,1,1-trifluoro-2-chloroethane (HCFC-133a) were chosen as models for comparative metabolism studies on 1,1,1,2-tetrahaloethanes, which are under consideration as replacements for ozone-depleting chlorofluorocarbons (CFCs). Male Fischer 344 rats were given 10 mmol/kg ip HCFC-131a or HCFC-132b or exposed by inhalation to 1% HCFC-133a for 2 h. Urine collected in the first 24 h after exposure was analyzed by 19F NMR and GC/MS and with a fluoride-selective ion electrode for the formation of fluorine-containing metabolites. Metabolites of HCFC-131a included 2,2-dichloro-2-fluoroethyl glucuronide, 2,2-dichloro-2-fluoroethyl sulfate, dichlorofluoroacetic acid, and inorganic fluoride. Metabolites of HCFC-132b were characterized as 2-chloro-2,2-difluoroethyl glucuronide, 2-chloro-2,2-difluoroethyl sulfate, chlorodifluoroacetic acid, chlorodifluoroacetaldehyde hydrate, chlorodifluoroacetaldehyde-urea adduct, and inorganic fluoride. HCFC-133a was metabolized to 2,2,2-trifluoroethyl glucuronide, trifluoroacetic acid, trifluoroacetaldehyde hydrate, trifluoroacetaldehyde-urea adduct, inorganic fluoride, and a minor, unidentified metabolite. With HCFC-131a and HCFC-132b, glucuronide conjugates of 2,2,2-trihaloethanols were the major urinary metabolites, whereas with HCFC-133a, a trifluoroacetaldehyde-urea adduct was the major urinary metabolite. Analysis of metabolite distribution in vivo indicated that aldehydic metabolites increased as fluorine substitution increased in the order HCFC-131a < HCFC-132b < HCFC-133a. With NADPH-fortified rat liver microsomes, HCFC-133a and HCFC-132b were biotransformed to trifluoroacetaldehyde and chlorodifluoroacetaldehyde, respectively, whereas HCFC-131a was converted to dichlorofluoroacetic acid. No covalently bound metabolites were detected by 19F NMR spectroscopy.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7766810

  20. Safety in the Laboratory: 1,1,1-Trichloroethane.

    ERIC Educational Resources Information Center

    Rothchild, Robert

    1983-01-01

    Discusses use of 1,1,1-trichloroethane as a substitute for carbon tetrachloride. Provides information on additives to commercially supplied sources in relation to possible reaction interferences. Warns of toxicity and possible carcinogenic action. (JM)

  1. 21 CFR 1.1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false General. 1.1 Section 1.1 Food and Drugs FOOD AND... General Provisions § 1.1 General. (a) The provisions of regulations promulgated under the Federal Food... promulgated under that act. (c) The definition of package in § 1.20 and of principal display panel in §§...

  2. 43 CFR 2812.1-1 - Filing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Filing. 2812.1-1 Section 2812.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-1 Filing. (a) An application for a permit for a right-of-way over the...

  3. 43 CFR 3452.1-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false General. 3452.1-1 Section 3452.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT..., and Termination § 3452.1-1 General. The lessee may surrender the entire lease, a legal...

  4. 45 CFR 1216.1-1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Purpose. 1216.1-1 Section 1216.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE NONDISPLACEMENT OF EMPLOYED WORKERS AND NONIMPAIRMENT OF CONTRACTS FOR SERVICE § 1216.1-1 Purpose. This...

  5. 45 CFR 1210.1-1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Purpose. 1210.1-1 Section 1210.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES General § 1210.1-1 Purpose. This...

  6. 43 CFR 3440.1-1 - Forms.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Forms. 3440.1-1 Section 3440.1-1 Public... OF THE INTERIOR MINERALS MANAGEMENT (3000) LICENSES TO MINE Licenses to Mine § 3440.1-1 Forms. (a... Bureau of Land Management State Office having jurisdiction over the lands involved (43 CFR subpart...

  7. 43 CFR 2812.1-1 - Filing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Filing. 2812.1-1 Section 2812.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-1 Filing. (a) An application for a permit for a right-of-way over the...

  8. 45 CFR 1220.1-1 - Introduction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Introduction. 1220.1-1 Section 1220.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PAYMENT OF VOLUNTEER LEGAL EXPENSES General § 1220.1-1 Introduction. Section 419 of the Domestic...

  9. 45 CFR 1220.1-1 - Introduction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Introduction. 1220.1-1 Section 1220.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PAYMENT OF VOLUNTEER LEGAL EXPENSES General § 1220.1-1 Introduction. Section 419 of the Domestic...

  10. 43 CFR 2812.1-1 - Filing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Filing. 2812.1-1 Section 2812.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-1 Filing. (a) An application for a permit for a right-of-way over the...

  11. 43 CFR 3191.1-1 - Petition.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Petition. 3191.1-1 Section 3191.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... CONTRACTS FOR OIL AND GAS INSPECTION Delegation of Authority § 3191.1-1 Petition. The Governor or...

  12. IRIS Update Batch 1, Group 1

    EPA Science Inventory

    Update the following IRIS chemical dose-response assessments: Barium (cancer, RfC), o-Cresol (RfD, cancer), carbon disulfied (RfD, RfC), 1,1-Dichloroethane (cancer), 2,4-Dimethylphenol (RfD), 1,4-Dibromobenzene (RfD), 1-chloro-1,1-difluroelfane (RfC, Acetyl chloride (cancer),2,4...

  13. 26 CFR 1.875-1 - Partnerships.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Partnerships. 1.875-1 Section 1.875-1 Internal... TAXES Nonresident Aliens and Foreign Corporations § 1.875-1 Partnerships. Whether a nonresident alien individual who is a member of a partnership is taxable in accordance with subsection (a), (b), or (c)...

  14. 45 CFR 1211.1-1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Purpose. 1211.1-1 Section 1211.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-1 Purpose. This part establishes procedures under which certain...

  15. 45 CFR 1211.1-1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Purpose. 1211.1-1 Section 1211.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-1 Purpose. This part establishes procedures under which certain...

  16. 26 CFR 1.581-1 - Banks.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Banks. 1.581-1 Section 1.581-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Banking Institutions § 1.581-1 Banks. (a) In order to be a bank as defined in section 581,...

  17. 43 CFR 3452.1-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false General. 3452.1-1 Section 3452.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT..., and Termination § 3452.1-1 General. The lessee may surrender the entire lease, a legal...

  18. 43 CFR 3440.1-1 - Forms.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Forms. 3440.1-1 Section 3440.1-1 Public... OF THE INTERIOR MINERALS MANAGEMENT (3000) LICENSES TO MINE Licenses to Mine § 3440.1-1 Forms. (a... Bureau of Land Management State Office having jurisdiction over the lands involved (43 CFR subpart...

  19. 43 CFR 3191.1-1 - Petition.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Petition. 3191.1-1 Section 3191.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... CONTRACTS FOR OIL AND GAS INSPECTION Delegation of Authority § 3191.1-1 Petition. The Governor or...

  20. 26 CFR 1.936-1 - Elections.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 10 2011-04-01 2011-04-01 false Elections. 1.936-1 Section 1.936-1 Internal... TAXES (CONTINUED) Possessions of the United States § 1.936-1 Elections. (a) Making an election. A domestic corporation shall make an election under section 936(e), for any taxable year beginning...

  1. 26 CFR 1.936-1 - Elections.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 10 2013-04-01 2013-04-01 false Elections. 1.936-1 Section 1.936-1 Internal... TAXES (CONTINUED) Possessions of the United States § 1.936-1 Elections. (a) Making an election. A domestic corporation shall make an election under section 936(e), for any taxable year beginning...

  2. 26 CFR 1.936-1 - Elections.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 10 2012-04-01 2012-04-01 false Elections. 1.936-1 Section 1.936-1 Internal... TAXES (CONTINUED) Possessions of the United States § 1.936-1 Elections. (a) Making an election. A domestic corporation shall make an election under section 936(e), for any taxable year beginning...

  3. 26 CFR 1.936-1 - Elections.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 10 2014-04-01 2013-04-01 true Elections. 1.936-1 Section 1.936-1 Internal... TAXES (CONTINUED) Possessions of the United States § 1.936-1 Elections. (a) Making an election. A domestic corporation shall make an election under section 936(e), for any taxable year beginning...

  4. 26 CFR 1.936-1 - Elections.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false Elections. 1.936-1 Section 1.936-1 Internal... TAXES Possessions of the United States § 1.936-1 Elections. (a) Making an election. A domestic corporation shall make an election under section 936(e), for any taxable year beginning after December...

  5. 26 CFR 1.581-1 - Banks.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 7 2012-04-01 2012-04-01 false Banks. 1.581-1 Section 1.581-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Banking Institutions § 1.581-1 Banks. (a) In order to be a bank as defined in section 581,...

  6. 26 CFR 1.581-1 - Banks.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Banks. 1.581-1 Section 1.581-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Banking Institutions § 1.581-1 Banks. (a) In order to be a bank as defined in section 581,...

  7. 26 CFR 1.581-1 - Banks.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 7 2013-04-01 2013-04-01 false Banks. 1.581-1 Section 1.581-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Banking Institutions § 1.581-1 Banks. (a) In order to be a bank as defined in section 581,...

  8. 43 CFR 9185.1-1 - Surveys.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Surveys. 9185.1-1 Section 9185.1-1 Public... OF THE INTERIOR TECHNICAL SERVICES (9000) CADASTRAL SURVEY Instructions and Methods § 9185.1-1 Surveys. (a) Original surveys. Application for the original extension of the rectangular system of...

  9. 43 CFR 9185.1-1 - Surveys.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Surveys. 9185.1-1 Section 9185.1-1 Public... OF THE INTERIOR TECHNICAL SERVICES (9000) CADASTRAL SURVEY Instructions and Methods § 9185.1-1 Surveys. (a) Original surveys. Application for the original extension of the rectangular system of...

  10. 43 CFR 9185.1-1 - Surveys.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Surveys. 9185.1-1 Section 9185.1-1 Public... OF THE INTERIOR TECHNICAL SERVICES (9000) CADASTRAL SURVEY Instructions and Methods § 9185.1-1 Surveys. (a) Original surveys. Application for the original extension of the rectangular system of...

  11. 1 CFR 16.1 - Designation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Designation. 16.1 Section 16.1 General... DOCUMENTS AGENCY REPRESENTATIVES § 16.1 Designation. (a) Each agency shall designate, from its officers or...: (1) A liaison officer and an alternate. (2) A certifying officer and an alternate. (3) An...

  12. 1 CFR 20.1 - Liaison officers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Liaison officers. 20.1 Section 20.1 General... DOCUMENTS HANDLING OF THE UNITED STATES GOVERNMENT MANUAL STATEMENTS § 20.1 Liaison officers. (a) Each of... United States Government Manual: (1) Agencies of the legislative and judicial branches. (2)...

  13. 1 CFR 5.1 - Publication policy.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Publication policy. 5.1 Section 5.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.1 Publication...: (1) Executive orders, proclamations, and other Presidential documents. (2) Documents required to...

  14. 1 CFR 19.1 - Form.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Form. 19.1 Section 19.1 General Provisions... ORDERS AND PRESIDENTIAL PROCLAMATIONS § 19.1 Form. Proposed Executive orders and proclamations shall be... Tracts of Land for Use in Executive Orders and Proclamations,”1 prepared by the Bureau of Land...

  15. 1 CFR 16.1 - Designation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Designation. 16.1 Section 16.1 General... DOCUMENTS AGENCY REPRESENTATIVES § 16.1 Designation. (a) Each agency shall designate, from its officers or...: (1) A liaison officer and an alternate. (2) A certifying officer and an alternate. (3) An...

  16. 1 CFR 20.1 - Liaison officers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Liaison officers. 20.1 Section 20.1 General... DOCUMENTS HANDLING OF THE UNITED STATES GOVERNMENT MANUAL STATEMENTS § 20.1 Liaison officers. (a) Each of... United States Government Manual: (1) Agencies of the legislative and judicial branches. (2)...

  17. 1 CFR 19.1 - Form.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Form. 19.1 Section 19.1 General Provisions... ORDERS AND PRESIDENTIAL PROCLAMATIONS § 19.1 Form. Proposed Executive orders and proclamations shall be... Tracts of Land for Use in Executive Orders and Proclamations,”1 prepared by the Bureau of Land...

  18. 1 CFR 5.1 - Publication policy.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Publication policy. 5.1 Section 5.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.1 Publication...: (1) Executive orders, proclamations, and other Presidential documents. (2) Documents required to...

  19. 1 CFR 19.1 - Form.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Form. 19.1 Section 19.1 General Provisions... ORDERS AND PRESIDENTIAL PROCLAMATIONS § 19.1 Form. Proposed Executive orders and proclamations shall be... Tracts of Land for Use in Executive Orders and Proclamations,”1 prepared by the Bureau of Land...

  20. 1 CFR 20.1 - Liaison officers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Liaison officers. 20.1 Section 20.1 General... DOCUMENTS HANDLING OF THE UNITED STATES GOVERNMENT MANUAL STATEMENTS § 20.1 Liaison officers. (a) Each of... United States Government Manual: (1) Agencies of the legislative and judicial branches. (2)...

  1. 1 CFR 16.1 - Designation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Designation. 16.1 Section 16.1 General... DOCUMENTS AGENCY REPRESENTATIVES § 16.1 Designation. (a) Each agency shall designate, from its officers or...: (1) A liaison officer and an alternate. (2) A certifying officer and an alternate. (3) An...

  2. 1 CFR 5.1 - Publication policy.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Publication policy. 5.1 Section 5.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.1 Publication...: (1) Executive orders, proclamations, and other Presidential documents. (2) Documents required to...

  3. 26 CFR 1.581-1 - Banks.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Banks. 1.581-1 Section 1.581-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Banking Institutions § 1.581-1 Banks. (a) In order to be a bank as defined in section 581,...

  4. 45 CFR 1210.1-1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Purpose. 1210.1-1 Section 1210.1-1 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES General § 1210.1-1 Purpose. This...

  5. 26 CFR 1.1481-1 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 12 2014-04-01 2014-04-01 false 1.1481-1 Section 1.1481-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Mitigation of Effect of Renegotiation of Government Contracts § 1.1481-1 Tax on Transfers...

  6. 1 CFR 5.1 - Publication policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Publication policy. 5.1 Section 5.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.1 Publication...: (1) Executive orders, proclamations, and other Presidential documents. (2) Documents required to...

  7. 1 CFR 16.1 - Designation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Designation. 16.1 Section 16.1 General... DOCUMENTS AGENCY REPRESENTATIVES § 16.1 Designation. (a) Each agency shall designate, from its officers or...: (1) A liaison officer and an alternate. (2) A certifying officer and an alternate. (3) An...

  8. 1 CFR 5.1 - Publication policy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Publication policy. 5.1 Section 5.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.1 Publication...: (1) Executive orders, proclamations, and other Presidential documents. (2) Documents required to...

  9. 1 CFR 20.1 - Liaison officers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Liaison officers. 20.1 Section 20.1 General... DOCUMENTS HANDLING OF THE UNITED STATES GOVERNMENT MANUAL STATEMENTS § 20.1 Liaison officers. (a) Each of... United States Government Manual: (1) Agencies of the legislative and judicial branches. (2)...

  10. 1 CFR 19.1 - Form.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Form. 19.1 Section 19.1 General Provisions... ORDERS AND PRESIDENTIAL PROCLAMATIONS § 19.1 Form. Proposed Executive orders and proclamations shall be... Tracts of Land for Use in Executive Orders and Proclamations,”1 prepared by the Bureau of Land...

  11. 1 CFR 20.1 - Liaison officers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Liaison officers. 20.1 Section 20.1 General... DOCUMENTS HANDLING OF THE UNITED STATES GOVERNMENT MANUAL STATEMENTS § 20.1 Liaison officers. (a) Each of... United States Government Manual: (1) Agencies of the legislative and judicial branches. (2)...

  12. 1 CFR 19.1 - Form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Form. 19.1 Section 19.1 General Provisions... ORDERS AND PRESIDENTIAL PROCLAMATIONS § 19.1 Form. Proposed Executive orders and proclamations shall be... Tracts of Land for Use in Executive Orders and Proclamations,”1 prepared by the Bureau of Land...

  13. 1 CFR 16.1 - Designation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Designation. 16.1 Section 16.1 General... DOCUMENTS AGENCY REPRESENTATIVES § 16.1 Designation. (a) Each agency shall designate, from its officers or...: (1) A liaison officer and an alternate. (2) A certifying officer and an alternate. (3) An...

  14. 26 CFR 1.535-1 - Definition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Definition. 1.535-1 Section 1.535-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Corporations Used to Avoid Income Tax on Shareholders § 1.535-1 Definition. (a)...

  15. Electron Excitation Cross Sections for the C II Transitions 2s(exp 2)2p P-2(exp 0) yields 2s2p(exp 2) P-4, D-2, and S-2

    NASA Technical Reports Server (NTRS)

    Smith, Steven J.; Zuo, M.; Chutjian, A.; Tayal, S. S.; Williams, I. D.

    1996-01-01

    Experimental and theoretical excitation cross sections are reported for the transitions 2s(exp 2) 2p-2(exp 0) yield 2s2p(exp 2)P-4, D-2, and S-2 in C II. The transition wavelengths (energies) are 2324 A (5.34 eV), 1335 x (9.29 eV), and 1036 A (11.97 eV), respectively. Use is made of electron energy-loss and merged beams methods. The energy range covered is from below each threshold (4 - 11 eV) to 15-24 eV. As in previous work with O II, care was taken to assess and minimize the metastable fraction in the C II beam, to account for contributions from nearby energy-loss features, and to collect the full angular range of inelastically scattered electrons. A comparison is made for each transition between experiment and new 8-state R-matrix calculations. Subject headings: atomic data ultraviolet: general

  16. 43 CFR 3135.1-1 - Transfers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Transfers. 3135.1-1 Section 3135.1-1... Transfers, Extensions, Consolidations, and Suspensions § 3135.1-1 Transfers. (a) Subject to approval of the... subdivision, to anyone qualified under §§ 3130.1 and 3132.4 of this title to hold a lease. (b) Any...

  17. 43 CFR 3135.1-1 - Transfers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Transfers. 3135.1-1 Section 3135.1-1... Transfers, Extensions, Consolidations, and Suspensions § 3135.1-1 Transfers. (a) Subject to approval of the... subdivision, to anyone qualified under §§ 3130.1 and 3132.4 of this title to hold a lease. (b) Any...

  18. 43 CFR 3135.1-1 - Transfers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Transfers. 3135.1-1 Section 3135.1-1... Transfers, Extensions, Consolidations, and Suspensions § 3135.1-1 Transfers. (a) Subject to approval of the... subdivision, to anyone qualified under §§ 3130.1 and 3132.4 of this title to hold a lease. (b) Any...

  19. The Radial Distribution of Star Formation in Galaxies at Z approximately 1 from the 3D-HST Survey

    NASA Technical Reports Server (NTRS)

    Nelson, Erica June; vanDokkum, Pieter G.; Momcheva, Ivelina; Brammer, Gabriel; Lundgren, Britt; Skelton, Rosalind E.; Whitaker, Katherine E.; DaCunha, Elisabete; Schreiber, Natascha Foerster; Franx, Marijn; Fumagalli, Mattia; Kriek, Mariska; Labbe, Ivo; Leja, Joel; Patel, Shannon; Rix, Hans-Walter; Schmidt, Kasper B.; vanderWel, Argen; Wuyts, Stijn

    2013-01-01

    The assembly of galaxies can be described by the distribution of their star formation as a function of cosmic time. Thanks to the WFC3 grism on the Hubble Space Telescope (HST) it is now possible to measure this beyond the local Universe. Here we present the spatial distribution of H emission for a sample of 54 strongly star-forming galaxies at z 1 in the 3D-HST Treasury survey. By stacking the H emission, we find that star formation occurred in approximately exponential distributions at z approximately 1, with a median Sersic index of n = 1.0 +/- 0.2. The stacks are elongated with median axis ratios of b/a = 0.58 +/- 0.09 in H consistent with (possibly thick) disks at random orientation angles. Keck spectra obtained for a subset of eight of the galaxies show clear evidence for rotation, with inclination corrected velocities of 90.330 km s(exp 1-). The most straightforward interpretation of our results is that star formation in strongly star-forming galaxies at z approximately 1 generally occurred in disks. The disks appear to be scaled-up versions of nearby spiral galaxies: they have EW(H alpha) at approximately 100 A out to the solar orbit and they have star formation surface densities above the threshold for driving galactic scale winds.

  20. Vapor-liquid equilibria for the systems composed of 1-chloro-1,1-difluoroethane, 1,1-dichloro-1-fluoroethane, and 1,1,1-trichloroethane at 50.1 C

    SciTech Connect

    Kang, Y.W.; Lee, Y.Y.

    1996-03-01

    Isothermal vapor-liquid equilibria for the three binary systems 1-chloro-1,1-difluoroethane + 1,1-dichloro-1-fluoroethane, 1-chloro-1,1-difluoroethane + 1,1,1-trichloroethane, and 1,1-dichloro-1-fluoroethane + 1,1,1-trichloroethane and the ternary system 1-chloro-1,1-difluoromethane + 1,1-dichloro-1-fluoroethane + 1,1,1-trichloroethane have been measured at 50.1 C. The experimental data for the binary systems are correlated with the Peng-Robinson equation of state, and the relevant parameters are presented. The predicted results for the ternary system were found to be in good agreement with the experimental data.

  1. 1 CFR 51.1 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Register Act (1 CFR Ch. I); and (4) The acts which require publication in the Federal Register (See CFR volume entitled “CFR Index and Finding Aids.”) (c) The Director will assume in carrying out the... 1 General Provisions 1 2012-01-01 2012-01-01 false Policy. 51.1 Section 51.1 General...

  2. 9 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... term includes carnivals, circuses, animal acts, zoos, and educational exhibits, exhibiting such animals... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Definitions. 1.1 Section 1.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  3. 9 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... term includes carnivals, circuses, animal acts, zoos, and educational exhibits, exhibiting such animals... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Definitions. 1.1 Section 1.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  4. 9 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... term includes carnivals, circuses, animal acts, zoos, and educational exhibits, exhibiting such animals... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Definitions. 1.1 Section 1.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  5. 9 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... term includes carnivals, circuses, animal acts, zoos, and educational exhibits, exhibiting such animals... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Definitions. 1.1 Section 1.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  6. 9 CFR 1.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... term includes carnivals, circuses, animal acts, zoos, and educational exhibits, exhibiting such animals... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Definitions. 1.1 Section 1.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  7. 48 CFR 1.602-1 - Authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Authority. 1.602-1 Section 1.602-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority, and Responsibilities...

  8. 1 CFR 3.1 - Information services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Information services. 3.1 Section 3.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL SERVICES TO THE PUBLIC § 3.1 Information services. Except in cases where the time required would be excessive, information concerning...

  9. 1 CFR 12.1 - Federal Register.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... PUBLICATIONS OFFICIAL DISTRIBUTION WITHIN FEDERAL GOVERNMENT § 12.1 Federal Register. (a) Copies of the daily... Federal Register Index and LSA (List of CFR Sections Affected) are included with each Federal Register... 1 General Provisions 1 2014-01-01 2012-01-01 true Federal Register. 12.1 Section 12.1...

  10. 1 CFR 12.1 - Federal Register.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... PUBLICATIONS OFFICIAL DISTRIBUTION WITHIN FEDERAL GOVERNMENT § 12.1 Federal Register. (a) Copies of the daily... Federal Register Index and LSA (List of CFR Sections Affected) are included with each Federal Register... 1 General Provisions 1 2013-01-01 2012-01-01 true Federal Register. 12.1 Section 12.1...

  11. 1 CFR 12.1 - Federal Register.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... PUBLICATIONS OFFICIAL DISTRIBUTION WITHIN FEDERAL GOVERNMENT § 12.1 Federal Register. (a) Copies of the daily... Federal Register Index and LSA (List of CFR Sections Affected) are included with each Federal Register... 1 General Provisions 1 2012-01-01 2012-01-01 false Federal Register. 12.1 Section 12.1...

  12. 48 CFR 1.602-1 - Authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Authority. 1.602-1 Section 1.602-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority, and Responsibilities...

  13. 1 CFR 8.1 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Policy. 8.1 Section 8.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER CODE OF FEDERAL REGULATIONS § 8.1 Policy. (a) Pursuant to chapter 15 of title 44, United States Code, the Director of...

  14. 1 CFR 3.1 - Information services.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Information services. 3.1 Section 3.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL SERVICES TO THE PUBLIC § 3.1 Information services. Except in cases where the time required would be excessive, information concerning...

  15. 1 CFR 3.1 - Information services.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Information services. 3.1 Section 3.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL SERVICES TO THE PUBLIC § 3.1 Information services. Except in cases where the time required would be excessive, information concerning...

  16. 1 CFR 10.1 - Publication required.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Publication required. 10.1 Section 10.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Regular Publication § 10.1 Publication required. The Director publishes a special...

  17. 1 CFR 3.1 - Information services.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Information services. 3.1 Section 3.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL SERVICES TO THE PUBLIC § 3.1 Information services. Except in cases where the time required would be excessive, information concerning...

  18. 1 CFR 21.1 - Drafting.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Drafting. 21.1 Section 21.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS PREPARATION OF DOCUMENTS SUBJECT TO CODIFICATION General § 21.1 Drafting. (a) Each agency that prepares...

  19. 1 CFR 304.1 - General provisions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false General provisions. 304.1 Section 304.1 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.1 General provisions. (a) This...

  20. 1 CFR 456.1 - Introduction.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Introduction. 456.1 Section 456.1 General Provisions MISCELLANEOUS AGENCIES NATIONAL CAPITAL PLANNING COMMISSION (FREEDOM OF INFORMATION ACT REGULATIONS) § 456.1 Introduction. The following regulations implement the Freedom of Information Act,...

  1. 1 CFR 10.1 - Publication required.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Publication required. 10.1 Section 10.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Regular Publication § 10.1 Publication required. The Director publishes a special...

  2. 1 CFR 15.1 - Cooperation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Cooperation. 15.1 Section 15.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS SERVICES TO FEDERAL AGENCIES General § 15.1 Cooperation. The Director of the Federal...

  3. 1 CFR 304.1 - General provisions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true General provisions. 304.1 Section 304.1 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.1 General provisions. (a) This...

  4. 1 CFR 9.1 - Publication required.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Publication required. 9.1 Section 9.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER THE UNITED STATES GOVERNMENT MANUAL § 9.1 Publication required. (a) The Director publishes a special...

  5. 1 CFR 51.1 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Register Act (1 CFR Ch. I); and (4) The acts which require publication in the Federal Register (See CFR volume entitled “CFR Index and Finding Aids.”) (c) The Director will assume in carrying out the... 1 General Provisions 1 2014-01-01 2012-01-01 true Policy. 51.1 Section 51.1 General...

  6. 1 CFR 456.1 - Introduction.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Introduction. 456.1 Section 456.1 General Provisions MISCELLANEOUS AGENCIES NATIONAL CAPITAL PLANNING COMMISSION (FREEDOM OF INFORMATION ACT REGULATIONS) § 456.1 Introduction. The following regulations implement the Freedom of Information Act,...

  7. 1 CFR 21.1 - Drafting.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Drafting. 21.1 Section 21.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS PREPARATION OF DOCUMENTS SUBJECT TO CODIFICATION General § 21.1 Drafting. (a) Each agency that prepares...

  8. 1 CFR 21.1 - Drafting.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Drafting. 21.1 Section 21.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS PREPARATION OF DOCUMENTS SUBJECT TO CODIFICATION General § 21.1 Drafting. (a) Each agency that prepares...

  9. 1 CFR 8.1 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Policy. 8.1 Section 8.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER CODE OF FEDERAL REGULATIONS § 8.1 Policy. (a) Pursuant to chapter 15 of title 44, United States Code, the Director of...

  10. 1 CFR 10.1 - Publication required.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Publication required. 10.1 Section 10.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Regular Publication § 10.1 Publication required. The Director publishes a special...

  11. 1 CFR 8.1 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Policy. 8.1 Section 8.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER CODE OF FEDERAL REGULATIONS § 8.1 Policy. (a) Pursuant to chapter 15 of title 44, United States Code, the Director of...

  12. 1 CFR 51.1 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Register Act (1 CFR Ch. I); and (4) The acts which require publication in the Federal Register (See CFR volume entitled “CFR Index and Finding Aids.”) (c) The Director will assume in carrying out the... 1 General Provisions 1 2013-01-01 2012-01-01 true Policy. 51.1 Section 51.1 General...

  13. 1 CFR 15.1 - Cooperation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Cooperation. 15.1 Section 15.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS SERVICES TO FEDERAL AGENCIES General § 15.1 Cooperation. The Director of the Federal...

  14. 1 CFR 456.1 - Introduction.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Introduction. 456.1 Section 456.1 General Provisions MISCELLANEOUS AGENCIES NATIONAL CAPITAL PLANNING COMMISSION (FREEDOM OF INFORMATION ACT REGULATIONS) § 456.1 Introduction. The following regulations implement the Freedom of Information Act,...

  15. 1 CFR 15.1 - Cooperation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Cooperation. 15.1 Section 15.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS SERVICES TO FEDERAL AGENCIES General § 15.1 Cooperation. The Director of the Federal...

  16. 1 CFR 9.1 - Publication required.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Publication required. 9.1 Section 9.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER THE UNITED STATES GOVERNMENT MANUAL § 9.1 Publication required. (a) The Director publishes a special...

  17. 1 CFR 9.1 - Publication required.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Publication required. 9.1 Section 9.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER THE UNITED STATES GOVERNMENT MANUAL § 9.1 Publication required. (a) The Director publishes a special...

  18. 1 CFR 304.1 - General provisions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true General provisions. 304.1 Section 304.1 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.1 General provisions. (a) This...

  19. 1 CFR 10.1 - Publication required.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Publication required. 10.1 Section 10.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Regular Publication § 10.1 Publication required. The Director publishes a special...

  20. 1 CFR 8.1 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Policy. 8.1 Section 8.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER CODE OF FEDERAL REGULATIONS § 8.1 Policy. (a) Pursuant to chapter 15 of title 44, United States Code, the Director of...

  1. 1 CFR 15.1 - Cooperation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Cooperation. 15.1 Section 15.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS SERVICES TO FEDERAL AGENCIES General § 15.1 Cooperation. The Director of the Federal...

  2. 1 CFR 456.1 - Introduction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Introduction. 456.1 Section 456.1 General Provisions MISCELLANEOUS AGENCIES NATIONAL CAPITAL PLANNING COMMISSION (FREEDOM OF INFORMATION ACT REGULATIONS) § 456.1 Introduction. The following regulations implement the Freedom of Information Act,...

  3. 1 CFR 51.1 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Register Act (1 CFR Ch. I); and (4) The acts which require publication in the Federal Register (See CFR volume entitled “CFR Index and Finding Aids.”) (c) The Director will assume in carrying out the... 1 General Provisions 1 2010-01-01 2010-01-01 false Policy. 51.1 Section 51.1 General...

  4. 1 CFR 12.1 - Federal Register.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Federal Register Index and LSA (List of CFR Sections Affected) are included with each Federal Register... 1 General Provisions 1 2010-01-01 2010-01-01 false Federal Register. 12.1 Section 12.1 General... PUBLICATIONS OFFICIAL DISTRIBUTION WITHIN FEDERAL GOVERNMENT § 12.1 Federal Register. (a) Copies of the...

  5. 1 CFR 21.1 - Drafting.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Drafting. 21.1 Section 21.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS PREPARATION OF DOCUMENTS SUBJECT TO CODIFICATION General § 21.1 Drafting. (a) Each agency that prepares...

  6. 1 CFR 9.1 - Publication required.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Publication required. 9.1 Section 9.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER THE UNITED STATES GOVERNMENT MANUAL § 9.1 Publication required. The Director of the Federal Register...

  7. 1 CFR 21.1 - Drafting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Drafting. 21.1 Section 21.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS PREPARATION OF DOCUMENTS SUBJECT TO CODIFICATION General § 21.1 Drafting. (a) Each agency that prepares...

  8. 1 CFR 15.1 - Cooperation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Cooperation. 15.1 Section 15.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER PREPARATION, TRANSMITTAL, AND PROCESSING OF DOCUMENTS SERVICES TO FEDERAL AGENCIES General § 15.1 Cooperation. The Director of the Federal...

  9. 1 CFR 456.1 - Introduction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Introduction. 456.1 Section 456.1 General Provisions MISCELLANEOUS AGENCIES NATIONAL CAPITAL PLANNING COMMISSION (FREEDOM OF INFORMATION ACT REGULATIONS) § 456.1 Introduction. The following regulations implement the Freedom of Information Act,...

  10. 1 CFR 51.1 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Register Act (1 CFR Ch. I); and (4) The acts which require publication in the Federal Register (See CFR volume entitled “CFR Index and Finding Aids.”) (c) The Director will assume in carrying out the... 1 General Provisions 1 2011-01-01 2011-01-01 false Policy. 51.1 Section 51.1 General...

  11. 1 CFR 10.1 - Publication required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Publication required. 10.1 Section 10.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Regular Publication § 10.1 Publication required. The Director publishes a special...

  12. 1 CFR 9.1 - Publication required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Publication required. 9.1 Section 9.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER THE UNITED STATES GOVERNMENT MANUAL § 9.1 Publication required. The Director of the Federal Register...

  13. 1 CFR 3.1 - Information services.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Information services. 3.1 Section 3.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER GENERAL SERVICES TO THE PUBLIC § 3.1 Information services. Except in cases where the time required would be excessive, information concerning...

  14. 1 CFR 8.1 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Policy. 8.1 Section 8.1 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER CODE OF FEDERAL REGULATIONS § 8.1 Policy. (a) Pursuant to chapter 15 of title 44, United States Code, the Director of...

  15. 1 CFR 12.1 - Federal Register.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Federal Register Index and LSA (List of CFR Sections Affected) are included with each Federal Register... 1 General Provisions 1 2011-01-01 2011-01-01 false Federal Register. 12.1 Section 12.1 General... PUBLICATIONS OFFICIAL DISTRIBUTION WITHIN FEDERAL GOVERNMENT § 12.1 Federal Register. (a) Copies of the...

  16. Synthesis and acid-catalyzed transformations of 1-(1,6,6-trimethylbicyclo(2. 1. 1)hex-5-yl)-1-alkanones and 1-(1,6,6-trimethylbicyclo-(2. 1. 1)hex-5-yl)-1-alken-1-ones

    SciTech Connect

    Volkova, O.O.; Cherkaev, G.V.; Novikov, N.A.; Erman, M.B.; Aul'chenko, I.S.; Mochalin, V.B.

    1988-06-20

    The reaction of 1,6,6-trimethylbicyclo(2.1.1)hexane-5-carbaldehyde (photocitral B) with Grignard reagents followed by oxidation of the obtained alcohols gave 1-(1,6,6-trimethylbicyclo(2.1.1)hex-5-yl)-1-alkanones and 1-(1,6,6-trimethylbicyclo(2.1.1)hex-5-yl)-1-alken-1-ones, which isomerize to 1-(2,3,3-trimethyl-1-cyclopentenyl)-2-alkanones when heated in the presence of p-toluenesulfonic acid. It was shown that the intermediate compounds in this reaction are 1-(2,2,3-trimethyl-3-cyclopentenyl)-2-alkanones. Underanalogous conditions photocitral B isomerizes to /alpha/-campholenaldehyde.

  17. Ultraviolet Broad Absorption Features and the Spectral Energy Distribution of the QSO PG 1351+64. 3.1

    NASA Technical Reports Server (NTRS)

    Zheng, W.; Kriss, G. A.; Wang, J. X.; Brotherton, M.; Oegerle, W. R.; Blair, W. P.; Davidsen, A. F.; Green, R. F.; Hutchings, J. B.; Kaiser, M. E.; Fisher, R. (Technical Monitor)

    2001-01-01

    We present a moderate-resolution (approximately 20 km s(exp -1) spectrum of the mini broad absorption line QSO PG 1351+64 between 915-1180 A, obtained with the Far Ultraviolet Spectroscopic Explorer (FUSE). Additional low-resolution spectra at longer wavelengths were also obtained with the Hubble Space Telescope (HST) and ground-based telescopes. Broad absorption is present on the blue wings of C III (lambda)977, Ly(beta), O VI (lambda)(lambda)1032,1038, Ly(alpha), N V (lambda)(lambda)1238,1242, Si IV (lambda)(lambda)1393,1402, and C IV (lambda)(lambda)1548,1450. The absorption profile can be fitted with five components at velocities of approximately -780, -1049, -1629, -1833, and -3054 km s(exp -1) with respect to the emission-line redshift of z = 0.088. All the absorption components cover a large fraction of the continuum source as well as the broad-line region. The O VI emission feature is very weak, and the O VI/Ly(alpha) flux ratio is 0.08, one of the lowest among low-redshift active galaxies and QSOs. The UV (ultraviolet) continuum shows a significant change in slope near 1050 A in the restframe. The steeper continuum shortward of the Lyman limit extrapolates well to the observed weak X-ray flux level. The absorbers' properties are similar to those of high-redshift broad absorption-line QSOs. The derived total column density of the UV absorbers is on the order of 10(exp 21) cm(exp -2), unlikely to produce significant opacity above 1 keV in the X-ray. Unless there is a separate, high-ionization X-ray absorber, the QSO's weak X-ray flux may be intrinsic. The ionization level of the absorbing components is comparable to that anticipated in the broad-line region, therefore the absorbers may be related to broad-line clouds along the line of sight.

  18. 43 CFR 3109.1-1 - Generally.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Generally. 3109.1-1 Section 3109.1-1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL AND GAS LEASING Leasing Under Special Acts § 3109.1-1 Generally. The Act of May 21, 1930 (30 U.S.C. 301-306), authorizes either the leasing of oil...

  19. 43 CFR 3109.1-1 - Generally.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Generally. 3109.1-1 Section 3109.1-1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL AND GAS LEASING Leasing Under Special Acts § 3109.1-1 Generally. The Act of May 21, 1930 (30 U.S.C. 301-306), authorizes either the leasing of oil...

  20. 43 CFR 3109.1-1 - Generally.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Generally. 3109.1-1 Section 3109.1-1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL AND GAS LEASING Leasing Under Special Acts § 3109.1-1 Generally. The Act of May 21, 1930 (30 U.S.C. 301-306), authorizes either the leasing of oil...

  1. Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.

    PubMed

    Vachal, Petr; Toth, Leslie M; Hale, Jeffrey J; Yan, Lin; Mills, Sander G; Chrebet, Gary L; Koehane, Carol A; Hajdu, Richard; Milligan, James A; Rosenbach, Mark J; Mandala, Suzanne

    2006-07-15

    Novel series of sphingosine-1-phosphate (S1P) receptor agonists were developed through a systematic SAR aimed to achieve high selectivity for a single member of the S1P family of receptors, S1P1. The optimized structure represents a highly S1P1-selective and efficacious agonist: S1P1/S1P2, S1P1/S1P3, S1P1/S1P4>10,000-fold, S1P1/S1P5>600-fold, while EC50 (S1P1) <0.2 nM. In vivo experiments are consistent with S1P1 receptor agonism alone being sufficient for achieving desired lymphocyte-lowering effect.

  2. 48 CFR 1.603-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority, and Responsibilities 1.603-1 General... procurement career management program and a system for the selection, appointment, and termination...

  3. APE1/Ref-1: versatility in progress.

    PubMed

    Jeon, Byeong Hwa; Irani, Kaikobad

    2009-03-01

    Apurinic/apyrimidinic endonuclease1/redox factor-1 (APE1/Ref-1) is a multifunctional protein involved in base excision DNA repair and in transcriptional regulation of gene expression. Over the past decade and a half, knowledge of the biological functions, interactions, mechanisms of action, and regulation of the protein APE1/Ref-1 has grown exponentially. The multifunctional nature of APE1/Ref-1 is uncovering and has been extensively studied in the cellular response against oxidative stress. Recent evidence shows a biological role of APE1/Ref-1 can be modulated by the different post-translational modification. Because of APE1/Ref-1 importance to genomic stability and cell survival, APE1/Ref-1 is focused as the leading therapeutic target molecule for the oxidative stress condition or pathologic conditions such as cancer. This forum, dedicated to APE1/Ref-1, provides ample testimony that even though we have learned a great deal about APE1/Ref-1 over the past 15-plus years, our knowledge still constitutes the tip of the iceberg when it comes to understanding this versatile protein.

  4. 48 CFR 1.603-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ACQUISITION REGULATIONS SYSTEM Career Development, Contracting Authority, and Responsibilities 1.603-1 General... procurement career management program and a system for the selection, appointment, and termination...

  5. Inhibited 1,1,1-trichloroethane replaces trichloroethylene for degreasing

    NASA Technical Reports Server (NTRS)

    Schuler, F. T.

    1970-01-01

    In fight against air pollution inhibited TCE /1,1,1-trichloroethane/ is effective substitute for trichloroethylene in degreasing plants. This chemical has only slight photochemical activity and causes little eye irritation. TCE is less toxic than trichloroethylene and can withstand production loads and conditions, or long term storage, without degradation.

  6. Transient Pressure Test Article (TPTA) 1.1 and 1.1A, volume 1

    NASA Technical Reports Server (NTRS)

    Rebells, Clarence A.

    1988-01-01

    This final test report presents the results obtained during the static hot firing and cold-gas high Q tests of the first Transient Pressure Test Article (TPTA) 1.1. The TPTA consisted of field test joints A and B, which were the original RSRM J-insulation configuration, with a metal capture feature. It also consisted of a flight configuration nozzle-to-case test joint (Joint D) with shorter vent slots. Fluorocarbon O-rings were used in all the test joints. The purpose of the TPTA tests is to evaluate and characterize the RSMR field and nozzle-to-case joints under the influence of ignition and strut loads during liftoff anf high Q. All objectives of the cold-gas high Q (TPTA 1.1A) test were met and all measurements were close to predicted values. During the static hot-firing test (TPTA 1.1), the motor was inadvertently plugged by the quench injector plug, making it a more severe test, although no strut loads were applied. The motor was depressurized after approximately 11 min using an auxiliary system, and no anomalies were noted. In the static hot-firing test, pressure was incident on the insulation and the test joint gaps were within the predicted range. During the static hot-firing test, no strut loads were applied because the loading system malfunctioned. For this test, all measurements were within range of similar tests performed without strut loads.

  7. 43 CFR 9185.1-1 - Surveys.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Surveys. 9185.1-1 Section 9185.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR TECHNICAL SERVICES (9000) CADASTRAL SURVEY Instructions and Methods §...

  8. Variant Humicola grisea CBH1.1

    DOEpatents

    Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

    2011-05-31

    Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

  9. Variant Humicola grisea CBH1.1

    DOEpatents

    Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

    2008-12-02

    Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

  10. Variant Humicola grisea CBH1.1

    DOEpatents

    Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

    2012-08-07

    Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

  11. Variant Humicola grisea CBH1.1

    DOEpatents

    Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

    2011-08-16

    Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

  12. Variant Humicola grisea CBH1.1

    SciTech Connect

    Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

    2014-03-18

    Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

  13. Variant humicola grisea CBH1.1

    SciTech Connect

    Goedegebuur, Frits; Gualfetti, Peter; Mitchinson, Colin; Edmund, Larenas

    2014-09-09

    Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

  14. 43 CFR 2812.1-1 - Filing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Filing. 2812.1-1 Section 2812.1-1 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) TRAMROADS AND LOGGING ROADS Over O. and C. and...

  15. Superconformal SU(1, 1|n) mechanics

    NASA Astrophysics Data System (ADS)

    Galajinsky, Anton; Lechtenfeld, Olaf

    2016-09-01

    Recent years have seen an upsurge of interest in dynamical realizations of the superconformal group SU(1, 1|2) in mechanics. Remarking that SU(1, 1|2) is a particular member of a chain of supergroups SU(1, 1| n) parametrized by an integer n, here we begin a systematic study of SU(1, 1| n) multi-particle mechanics. A representation of the superconformal algebra su(1, 1| n) is constructed on the phase space spanned by m copies of the (1, 2 n, 2 n-1) supermultiplet. We show that the dynamics is governed by two prepotentials V and F, and the Witten-Dijkgraaf-Verlinde-Verlinde equation for F shows up as a consequence of a more general fourth-order equation. All solutions to the latter in terms of root systems reveal decoupled models only. An extension of the dynamical content of the (1, 2 n, 2 n-1) supermultiplet by angular variables in a way similar to the SU(1, 1|2) case is problematic.

  16. 7 CFR 301.1-1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 5 2011-01-01 2011-01-01 false Definitions. 301.1-1 Section 301.1-1 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Preemption and Special Need Requests §...

  17. 7 CFR 301.1-1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Definitions. 301.1-1 Section 301.1-1 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Preemption and Special Need Requests §...

  18. Variant Humicola grisea CBH1.1

    SciTech Connect

    Goedegeburr, Frits; Gualfetti, Peter; Mitchinson, Colin; Larenas, Edmund

    2013-02-19

    Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.

  19. Get Ready for 1:1

    ERIC Educational Resources Information Center

    Moore, Darcy

    2009-01-01

    Good planning can make or break a successful 1:1 program. The author, a long-time deputy principal with extensive EdTech experience, shares his insights on how to get the most out of 1:1. Read these tips before getting started or improving an existing program.

  20. Analytic cross sections for 1 1S, to 1 1S to 2 1S, 1 1S to 2 1P transitions in helium by electron impact

    NASA Technical Reports Server (NTRS)

    Sukumar, C. V.; Faisal, F. H. M.

    1971-01-01

    The 1 1s yields 1 1s elastic and 1 1s yields 2 1s and 1 1s yields 2 excitation cross sections of Helium atoms by collision with a charged particle are obtained as analytic functions of incident velocity. The first order time dependent scattering theory is used. Numerical values of electron -He cross sections are obtained for incident energies in the range 30 eV to 800 eV and compared with earlier Born approximation calculations and with available experimental data. It is found that at 100 eV and above, the present results are in good agreement with the experimental results. They are also closer to the experimental results than the corresponding Born calculations.

  1. Angle-resolved photoemission study of Ag(1 1 1)

    NASA Astrophysics Data System (ADS)

    Edamoto, K.; Miyazaki, E.; Shimokoshi, K.; Kato, H.

    1990-01-01

    The (1 1 1) face of Ag has been studied by angle-resolved photoemission spectroscopy utilizing synchrotron radiation as the excitation source (25 <= hv <= 50eV). The overlapping Ag 4d bands were deconvolved by the modified FIRO method. The peak positions thus determined are used to map the dispersion curves along the lang1 1 1rang (Γ-L) direction. The results show general agreement with calculated band structure, so far as the energy levels and symmetries are concerned. However, it is found that the density of state effect is dominant in the spectra obtained in the present photon energy region. The emission from the Ag 5s, p bands is observed to be broadened due to the indirect transition process.

  2. Gompertz type dechanneling functions for protons in <1 0 0>, <1 1 0> and <1 1 1> Si crystal channels

    NASA Astrophysics Data System (ADS)

    Petrović, S.; Erić, M.; Kokkoris, M.; Nešković, N.

    2007-03-01

    In this work the energy dependences of the Gompertz type sigmoidal dechanneling function parameters for protons in <1 0 0>, <1 1 0> and <1 1 1> Si crystal channels is investigated theoretically. The proton energy range considered is between 1 and 10 MeV. The original dechanneling functions are generated using a realistic Monte Carlo computer simulation code. We show that the Gompertz type dechanneling function, having two parameters, lc and k, representing the dechanneling range and rate, respectively, approximate accurately the original dechanneling function. It is also shown that the energy dependences of parameters lc and k can be approximated by a linear function and a sum of two exponential functions, respectively. The results obtained can be used for accurate reproduction of experimental proton channeling spectra recorded in the backscattering geometry.

  3. H1N1 influenza (Swine flu)

    MedlinePlus

    ... regular (seasonal) flu vaccine. You cannot get H1N1 flu virus from eating pork or any other food, drinking ... pools, or using hot tubs or saunas. Any flu virus can spread from person to person when: Someone ...

  4. Alpha-1 Antitrypsin Deficiency

    MedlinePlus

    ... Liver Disease Information > Alpha-1 Antitrypsin Deficiency Alpha-1 Antitrypsin Deficiency Explore this section to learn more about alpha-1 antitrypsin deficiency, including a description of the disorder ...

  5. 26 CFR 1.316-1 - Dividends.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Definitions; Constructive Ownership of Stock § 1.316-1 Dividends. (a)(1) The term dividend for the... income tax law, was under the applicable law a personal holding company, the term dividend, in...

  6. From 1:1 to 1 to Won

    ERIC Educational Resources Information Center

    Hall, Don

    2006-01-01

    In this article, the author discusses on the emphasis of how 1:1 computing program transforms classroom and education experience for students. Moreover, the author stresses that with this type of program, they have created vision where the culture, curriculum, and chores were designed to meet the needs of the digital age students in terms of rigor…

  7. CHARICE version 1.1 update.

    SciTech Connect

    Davis, Jean-Paul

    2008-10-01

    CHARICE (CHARacteristics-based inverse analysis of Isentropic Compression Experiments) is a computer application, previously documented in SAND2007-4948, that analyzes velocity waveform data from ramp-wave experiments to determine a material's quasi-isentropic loading response in stress and density using an iterative characteristics-based approach. This short report documents only the changes in CHARICE release version 1.1 relative to release version 1.0, and is not intended to stand alone. CHARICE version 1.1 corrects an error in the algorithm of the method, fixes several bugs, improves robustness and performance, provides more useful error descriptions, and adds a number of minor features.

  8. Chapter 1: Epidemiology of Type 1 Diabetes

    PubMed Central

    Maahs, David M; West, Nancy A; Lawrence, Jean M.; Mayer-Davis, Elizabeth J

    2010-01-01

    Synopsis This chapter describes the epidemiology of type 1 diabetes mellitus (T1D) around the world and across the lifespan. Epidemiologic patterns of T1D by demographic, geographic, biologic, cultural and other factors in populations are presented to gain insight about the etiology, natural history, risks, and complications of T1D. Data from large epidemiologic studies worldwide indicate that the incidence of T1D has been increasing by 2–5% worldwide and that the prevalence of T1D is approximately 1 in 300 in the US by 18 years of age. Research on risk factors for T1D is an active area of research to identify genetic and environmental triggers that could potentially be targeted for intervention. While significant advances have been made in the clinical care of T1D with resultant improvements in quality of life and clinical outcomes, much more needs to be done to improve care of, and ultimately find a cure for T1D. Epidemiologic studies have an important on-going role to investigate the complex causes, clinical care, prevention, and cure of T1D. PMID:20723815

  9. First-principles phonon calculation for Al-(Re,Mn)-Si 1/1-1/1-1/1 approximants

    NASA Astrophysics Data System (ADS)

    Nagasako, N.; Asahi, R.; Takeuchi, T.

    2006-03-01

    A very low thermal conductivity (˜1 W/Km) and a relatively large Seebeck coefficient in Al-based Mackay-type icosahedral quasicrystal have attracted much interest aiming for thermoelectric applications. We performed first-principles phonon calculations for the Al-(Re,Mn)-Si 1/1-1/1-1/1 approximants [1] to elucidate mechanism of their low thermal conductivity. The total energy and atomic force were calculated for a modeled Al17(Re,Mn)4Si2 unit cell containing 138 atoms using the projector augmented wave method implemented in VASP code [2], and were then utilized for obtaining a phonon dispersion by the direct method [3]. The calculated lattice specific heat showed very good agreement with experiment, confirming validity of the present calculations. We found localized optical modes with a relatively low frequency (˜2 THz) in the phonon dispersion. We discuss the low thermal conductivity in comparison between the Al-Re-Si and Al-Mn-Si systems via averaged group velocity and umklapp phonon scattering related to these optical modes. [1] Takeuchi et al., Phys. Rev. B70, 144202 (2004). [2] G. Kresse, J. Furthmuller, Phys. Rev. B54, 11169 (1996). [3] MedeA-Phonon, Materials Design, Inc. (2003) based on K. Parlinski, Phonon 3.11 (2002).

  10. PDX-1 (pancreatic/duodenal homeobox-1 protein 1).

    PubMed

    Pedica, F; Beccari, S; Pedron, S; Montagna, L; Piccoli, P; Doglioni, C; Chilosi, M

    2014-12-01

    The homeodomain-containing transcription factor pancreatic duodenal homeobox 1 (PDX-1) plays a key role in pancreatic development and β-cell function. It is a major regulator of transcription in pancreatic cells, and transactivates the insulin gene by binding to a specific DNA motif in its promoter region. Glucose also regulates insulin gene transcription through PDX-1. It has been shown that PDX-1 is required for maintaining pancreatic islet functions by activating gene expression and has a dual role in pancreatic development. It initially contributes to pancreatic formation during embryogenesis and subsequently regulates the pancreatic islet cell physiology in mature islet cells. Because of this key role in the embryologic development of the pancreas, PDX-1 expression has been investigated in pancreatic cancer cell lines and human tumors. Moreover, a few reports have described expression of PDX-1 in other human neoplasms and have investigated its potential role in differential diagnosis, but data on normal human tissues are lacking. Understanding the molecular mechanisms of pancreas formation, and especially the function of PDX-1, may contribute to the improved treatment and prevention of debilitating diseases such as diabetes, insulinomas and pancreatic carcinomas. Nevertheless, further studies are needed concerning its possible application in routine practice.

  11. SealSim Version 1.1

    2005-05-16

    SealSim 1.1 is a state-of-the-art, Microsoft Windows based computer program developed for the U.S. Department of Energy by Aspen Research Corporation with Contracted support from TNO TPD. It is intended to be used by manufacturers, engineers, educators, students, architects, and others to help determine the relative durability of Insulating Glass Units (IGU). As a function of time, SealSim 1.1 simulates the behaviour of an Insulating Glass Unit, exposed to realistic or user-defined weather climates. Stressesmore » and strains in the IGU are calculated as a function of time, together with temperature distributions, gas permeation effects (gas loss, desiccant loading), dew point temperature, U-factor, etc. The current version of SealSim 1.1 supports double-glazing Units. where the spacer system is either a Thermo Plastic Spacer (TPS) or Box type spacer. For the determination of solar properties of glazing systems, SealSim 1.1 uses the Tntemational Glazing Database of LBNL, which is also used by OPTICS and WINDOW. The goal of the SealSim 1.1 simulations is to predict the IGU’s average lifetime, expressed in terms of the "Durability Index", together with the associated failure mechanisms. The Durability Index of a particular IGU and its most probable failure mechanism can be compared with other IGU’s. How the predicted Durability Index relates to the actual durability of an IGU is not known, simply because sufficient experimental data is lacking for describing the behaviour of IG Units over extended periods of time together with a lack of knowledge of the conditions it is subjected to and initial state of the CU at the time of manufacturing. In order to simulate the IGU behaviour in time, the conditions of the IGU must be defined; together with the weather and or climate that the IGU is subjected to. Using physical models of the IGU, SealSim 1.1 calculates tte response of the CU in time. These physical models are described in more detail in separate documents

  12. SealSim Version 1.1

    SciTech Connect

    2005-05-16

    SealSim 1.1 is a state-of-the-art, Microsoft Windows based computer program developed for the U.S. Department of Energy by Aspen Research Corporation with Contracted support from TNO TPD. It is intended to be used by manufacturers, engineers, educators, students, architects, and others to help determine the relative durability of Insulating Glass Units (IGU). As a function of time, SealSim 1.1 simulates the behaviour of an Insulating Glass Unit, exposed to realistic or user-defined weather climates. Stresses and strains in the IGU are calculated as a function of time, together with temperature distributions, gas permeation effects (gas loss, desiccant loading), dew point temperature, U-factor, etc. The current version of SealSim 1.1 supports double-glazing Units. where the spacer system is either a Thermo Plastic Spacer (TPS) or Box type spacer. For the determination of solar properties of glazing systems, SealSim 1.1 uses the Tntemational Glazing Database of LBNL, which is also used by OPTICS and WINDOW. The goal of the SealSim 1.1 simulations is to predict the IGU’s average lifetime, expressed in terms of the "Durability Index", together with the associated failure mechanisms. The Durability Index of a particular IGU and its most probable failure mechanism can be compared with other IGU’s. How the predicted Durability Index relates to the actual durability of an IGU is not known, simply because sufficient experimental data is lacking for describing the behaviour of IG Units over extended periods of time together with a lack of knowledge of the conditions it is subjected to and initial state of the CU at the time of manufacturing. In order to simulate the IGU behaviour in time, the conditions of the IGU must be defined; together with the weather and or climate that the IGU is subjected to. Using physical models of the IGU, SealSim 1.1 calculates tte response of the CU in time. These physical models are described in more detail in separate documents provided with

  13. Niemann-Pick C1 Like 1 (NPC1L1) an intestinal sterol transporter.

    PubMed

    Davis, Harry R; Altmann, Scott W

    2009-07-01

    Niemann-Pick C1 Like 1 (NPC1L1) has been identified and characterized as an essential protein in the intestinal cholesterol absorption process. NPC1L1 localizes to the brush border membrane of absorptive enterocytes in the small intestine. Intestinal expression of NPC1L1 is down regulated by diets containing high levels of cholesterol. While otherwise phenotypically normal, Npc1l1 null mice exhibit a significant reduction in the intestinal uptake and absorption of cholesterol and phytosterols. Characterization of the NPC1L1 pathway revealed that cholesterol absorption inhibitor ezetimibe specifically binds to an extracellular loop of NPC1L1 and inhibits its sterol transport function. Npc1l1 null mice are resistant to diet-induced hypercholesterolemia, and when crossed with apo E null mice, are completely resistant to the development of atherosclerosis. Intestinal gene expression studies in Npc1l1 null mice indicated that no exogenous cholesterol was entering enterocytes lacking NPC1L1, which resulted in an upregulation of intestinal and hepatic LDL receptor and cholesterol biosynthetic gene expression. Polymorphisms in the human NPC1L1 gene have been found to influence cholesterol absorption and plasma low density lipoprotein levels. Therefore, NPC1L1 is a critical intestinal sterol uptake transporter which influences whole body cholesterol homeostasis.

  14. Aryl morpholino triazenes inhibit cytochrome P450 1A1 and 1B1.

    PubMed

    Lee, Daniel; Perez, Pedro; Jackson, William; Chin, Taylor; Galbreath, Michael; Fronczek, Frank R; Isovitsch, Ralph; Iimoto, Devin S

    2016-07-15

    Many cytochrome P450 1A1 and 1B1 (CYP1A1 and CYP1B1) inhibitors, such as resveratrol, have planar, hydrophobic, aromatic rings in their structure and exhibit anti-cancer activity. Aryl morpholino triazenes have similar structural features and in addition contain a triazene unit consisting of three consecutive, conjugated nitrogen atoms. Several aryl morpholino triazenes, including 4-[(E)-2-(3,4,5-trimethoxyphenyl)diazenyl]-morpholine (2), were prepared from a reaction involving morpholine and a diazonium ion produced from different aniline derivatives, such as 3,4,5-trimethoxyaniline. The aryl morpholino triazenes were then screened at 100μM for their ability to inhibit CYP1A1 and CYP1B1 using ethoxyresorufin as the substrate. Triazenes that inhibited the enzymes to less than 80% of the uninhibited enzyme activity were assayed to determine their IC50 value. Compound 2 was the only triazene to inhibit both CYP1A1 and CYP1B1 to the same degree as resveratrol with IC50 values of 10μM and 18μM, respectively. Compounds 3 and 6 selectively inhibited CYP1B1 over CYP1A1 with IC values of 2μM and 7μM, respectively. Thus, aryl morpholino triazenes are a new class of compounds that can inhibit CYP1A1 and CYP1B1 and potentially prevent cancer. PMID:27265259

  15. 3-Quaternary ammonium 1-carba-1-dethiacephems.

    PubMed

    Cook, G K; McDonald, J H; Alborn, W; Boyd, D B; Eudaly, J A; Indelicato, J M; Johnson, R; Kasher, J S; Pasini, C E; Preston, D A

    1989-11-01

    A series of structurally unique 1-carba-1-dethiacephems is described. The structural stability of the 1-carba-1-dethiacephem nucleus was essential for the preparation of this series of 3-quaternary ammonium carbacephems. The known p-nitrobenzyl 7 beta-(phenoxyacetamido)- 3-[(trifluoromethyl)sulfonyl]oxy]-1-carba-1-dethia-3-cephem- 4-carboxylate served as both a quaternization substrate as well as a precursor to derivatives such as allyl 7 beta-[[2-[allyloxy)carbonyl]amino-4- thiazoly] (methoxyimino)acetyl]amino]-3-[(trifluoromethyl) sulfonyl] oxy]-1-carba-1-dethia-3-cephem-4-carboxylate. Quaternization of these enol triflates was accomplished either by dissolution in acetonitrile containing the base or by dissolution in the base, with or without warning to 50 degrees C. Bases nucleophilic enough to displace the triflate include a variety of substituted pyridines and N-methylimidazole. Deprotection then produced a very active series of 1-[7 beta-[(2-amino- 4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo- 1-azabicyclo[4.2.0]oct-2-en-3-yl] quaternary ammonium hydroxide inner salts. These compounds were extremely potent antibacterials against a broad range of Gram-positive and -negative bacteria including constitutive cephalosporinase producers, such as Enterobacter cloacae. The compounds exhibit similar hydrolysis kinetics and pharmacokinetics to the analogous cephalosporin-3'-quaternary ammonium salts.

  16. Construction of HEK293 cells stably expressing wild-type organic anion transporting polypeptide 1B1 (OATP1B1*1a) and variant OATP1B1*1b and OATP1B1*15.

    PubMed

    Chen, M; Qu, B X; Chen, X L; Hu, H H; Jiang, H D; Yu, L S; Zhou, Q; Zeng, S

    2016-06-01

    A transgenic cell line stably expressing the human organic anion transporting polypeptide (OATP1B1) was established. Human Embryonic Kidney 293 (HEK293) cell line stably expressing OATP1B1*1a sequence was amplified through PCR with the extracted total RNA as templates from human liver, then subcloned into the plasmid pMD19-T and verified by sequencing. OATP1B1*1b/OATP1B1*15 mutant sequences were obtained by site-directed mutation PCR with pMD19-T/ OATP1B1*1a as templates. The plasmids pcDNA3.1(+)/OATP1B1*1a, *1b and *15 were constructed and transfected into HEK293 cell line using Lipofectamine 2000 transfection reagent. Several stable transfected clones were obtained after selection with G418. Using rosuvastatin as a probe substrate of OATP1B1, the intracellular rosuvastatin accumulation in HEK293 and HEK-OATP1B1*1a, *1b and *15 monoclone cells were validated by a ultra-performance liquid chromatography-tandem mass spectrometry. OATP1B1 mRNA and protein expression were detected by RT-PCR and Western blot, respectively. The results from RT-PCR, rosuvastatin uptake and Western blot assay indicated that human OATP1B1 was highly expressed in transfected cells compared with controls. The HEK-293 cell lines stably expressing human OATP1B1-wild and variant (HEK-OATP1B1, *1b and *15) are potential models to study drug transport in vitro. PMID:27455553

  17. Construction of HEK293 cells stably expressing wild-type organic anion transporting polypeptide 1B1 (OATP1B1*1a) and variant OATP1B1*1b and OATP1B1*15.

    PubMed

    Chen, M; Qu, B X; Chen, X L; Hu, H H; Jiang, H D; Yu, L S; Zhou, Q; Zeng, S

    2016-06-01

    A transgenic cell line stably expressing the human organic anion transporting polypeptide (OATP1B1) was established. Human Embryonic Kidney 293 (HEK293) cell line stably expressing OATP1B1*1a sequence was amplified through PCR with the extracted total RNA as templates from human liver, then subcloned into the plasmid pMD19-T and verified by sequencing. OATP1B1*1b/OATP1B1*15 mutant sequences were obtained by site-directed mutation PCR with pMD19-T/ OATP1B1*1a as templates. The plasmids pcDNA3.1(+)/OATP1B1*1a, *1b and *15 were constructed and transfected into HEK293 cell line using Lipofectamine 2000 transfection reagent. Several stable transfected clones were obtained after selection with G418. Using rosuvastatin as a probe substrate of OATP1B1, the intracellular rosuvastatin accumulation in HEK293 and HEK-OATP1B1*1a, *1b and *15 monoclone cells were validated by a ultra-performance liquid chromatography-tandem mass spectrometry. OATP1B1 mRNA and protein expression were detected by RT-PCR and Western blot, respectively. The results from RT-PCR, rosuvastatin uptake and Western blot assay indicated that human OATP1B1 was highly expressed in transfected cells compared with controls. The HEK-293 cell lines stably expressing human OATP1B1-wild and variant (HEK-OATP1B1, *1b and *15) are potential models to study drug transport in vitro.

  18. High Resolution Infrared Spectroscopy of [1.1.1] Propellane

    SciTech Connect

    Kirkpatrick, Robynne W.; Masiello, Tony; Jariyasopit, Narumol; Weber, Alfons; Nibler, Joseph W.; Maki, Arthur; Blake, Thomas A.; Hubler, Timothy L.

    2008-01-08

    The infrared spectrum of [1.1.1]propellane has been recorded at high resolution (0.002 cm-1) with individual rovibrational lines resolved for the first time. This initial report presents the ground state constants for this molecule determined from the analysis of five of the eight infrared-allowed fundamentals v9(e'), v10(e'), v12(e'), v14(a2''), v15(a2''), as well as of several combination bands. In nearly all cases it was found that the upper states of the transitions exhibit some degree of perturbation but, by use of the combination difference method, the assigned frequencies provided over 4000 consistent ground state difference values. Analysis of these gave for the parameters of the ground state the following values, in cm-1: B0 = 0.28755833(14), DJ = 1.1313(5)x10-7, DJK = -1.2633(7)x10-7, HJ = 0.72(4)x10-13, HJK = -2.24(13)x10-13, and HKJ = 2.25(15)x10-13, where the numbers in parentheses indicate twice the uncertainties in the last quoted digit(s) of the parameters. Gaussian ab initio calculations, especially with the computed anharmonic corrections to some of the spectroscopic parameters, assisted in the assignments of the bands and also provided information on the electron distribution in the bridge-head carbon-carbon bond.

  19. Thermal decomposition of 1,1,1-trifluoroethane revisited.

    PubMed

    Matsugi, Akira; Yasunaga, Kenji; Shiina, Hiroumi

    2014-12-18

    1,1,1-Trifluoroethane (CH3CF3) has been frequently used as a chemical thermometer or an internal standard in shock tube studies to determine relative rates of chemical reactions. The rate constants for the thermal decomposition of CH3CF3 were recently reported to have anomalous pressure dependence in the high-temperature falloff region. In the present study, the kinetics of the CH3CF3 decomposition were reinvestigated using shock tube/laser absorption (ST/LA) spectroscopy and single-pulse shock tube (SPST) methods over the temperature range 1163-1831 K at pressures from 95 to 290 kPa. The present rate constants are 2-3 times smaller than those reported in previous single-pulse experiments performed at near high-pressure limit conditions. The recommended rate constant expression, k = 5.71 × 10(46)T(-9.341) exp(-47073 K/T) s(-1), was obtained over the temperature range 1000-1600 K with uncertainties of ±40% at temperatures below 1300 K and ±32% at 1600 K. The rate constants at the high-temperature region showed clear falloff behavior and were in good agreement with recent high-temperature experiments. The falloff rate constants could not be reproduced by a standard RRKM/master-equation model; this study provides additional evidence for the unusual pressure dependence previously reported for this reaction. Additionally, the rate constants for the decomposition of 1,1-difluoroethylene (CH2CF2) were determined over the temperature range 1650-2059 K at pressures of 100 and 205 kPa, and were reproduced by the RRKM/master-equation calculation with an average downward energy transfer of 900 cm(-1).

  20. Growth of monocrystalline Cu(1 1 1) films on MgO(1 1 1) by pulsed laser deposition

    NASA Astrophysics Data System (ADS)

    Aweke, F.; Antoni, F.; Hulik, J.; Morvan, G.; Speisser, C.; Veis, P.; Le Normand, F.

    2015-05-01

    Copper (Cu) films with a minimal thickness of 300 nm were grown on MgO(1 1 1) substrates in high vacuum by pulsed laser deposition (PLD) at various temperatures to achieve a single crystal Cu film with flat terraces without grain boundaries. We investigated the effect of the substrate temperature, the pulse repetition rate, the deposition time and the laser fluence. A temperature threshold is observed above which the growth mode is changed from a uniform flat mode to a three dimensional mode. A combined process involving a germination step at moderate temperature followed by a growth step at higher temperature yields a 450 nm almost continuous film.

  1. 26 CFR 1.165-1 - Losses.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... adjusted basis for determining the loss from the sale or other disposition of the property involved. In the... recognized upon the sale or exchange of property shall be determined for purposes of section 165(a) in accordance with § 1.1002-1. (3) A loss from the sale or exchange of a capital asset shall be allowed as...

  2. Ciencias 1. (Science 1). [Student's Workbook].

    ERIC Educational Resources Information Center

    Raposo, Lucilia

    Ciencias 1 is the first in a series of science books designed for elementary Portuguese-speaking students. The book contains five sections divided into 43 lessons. The five sections are (1) Matter, (2) The Human Body, (3) Weather, (4) Solids, Liquids, and Gases, and (5) Living Things. Pictorial presentations and picture exercises are included for…

  3. 1,1,2,2-Tetrachloroethane

    Integrated Risk Information System (IRIS)

    1,1,2,2 - Tetrachloroethane ; CASRN 79 - 34 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncar

  4. 26 CFR 1.801-1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... reserves (as defined in section 801). An insurance company writing only noncancellable life, health, or... premium” means the amount which will cover the cost of carrying the insurance risk for the period for... TAXES (CONTINUED) Life Insurance Companies § 1.801-1 Definitions. (a) Life insurance company. The...

  5. 26 CFR 1.801-1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... reserves (as defined in section 801). An insurance company writing only noncancellable life, health, or... premium” means the amount which will cover the cost of carrying the insurance risk for the period for... TAXES (CONTINUED) Life Insurance Companies § 1.801-1 Definitions. (a) Life insurance company. The...

  6. 26 CFR 1.801-1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... reserves (as defined in section 801). An insurance company writing only noncancellable life, health, or... premium” means the amount which will cover the cost of carrying the insurance risk for the period for... TAXES (CONTINUED) Life Insurance Companies § 1.801-1 Definitions. (a) Life insurance company. The...

  7. General Relativity in (1 + 1) Dimensions

    ERIC Educational Resources Information Center

    Boozer, A. D.

    2008-01-01

    We describe a theory of gravity in (1 + 1) dimensions that can be thought of as a toy model of general relativity. The theory should be a useful pedagogical tool, because it is mathematically much simpler than general relativity but shares much of the same conceptual structure; in particular, it gives a simple illustration of how gravity arises…

  8. 33 CFR 1.08-1 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... criminal penalty procedures under subpart 1.07 of this part: (1) 46 CFR 25.05 whistles or other sound producing devices; (2) 33 CFR part 175, subpart B and 46 CFR subpart 25.25, Personal Flotation Devices. (3) 46 CFR 25.35 backfire flame control; (4) 46 CFR 25.40 ventilation; (5) 33 CFR part 173 numbering;...

  9. 33 CFR 1.08-1 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... criminal penalty procedures under subpart 1.07 of this part: (1) 46 CFR 25.05 whistles or other sound producing devices; (2) 33 CFR part 175, subpart B and 46 CFR subpart 25.25, Personal Flotation Devices. (3) 46 CFR 25.35 backfire flame control; (4) 46 CFR 25.40 ventilation; (5) 33 CFR part 173 numbering;...

  10. 33 CFR 1.08-1 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... criminal penalty procedures under subpart 1.07 of this part: (1) 46 CFR 25.05 whistles or other sound producing devices; (2) 33 CFR part 175, subpart B and 46 CFR subpart 25.25, Personal Flotation Devices. (3) 46 CFR 25.35 backfire flame control; (4) 46 CFR 25.40 ventilation; (5) 33 CFR part 173 numbering;...

  11. 33 CFR 1.08-1 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... criminal penalty procedures under subpart 1.07 of this part: (1) 46 CFR 25.05 whistles or other sound producing devices; (2) 33 CFR part 175, subpart B and 46 CFR subpart 25.25, Personal Flotation Devices. (3) 46 CFR 25.35 backfire flame control; (4) 46 CFR 25.40 ventilation; (5) 33 CFR part 173 numbering;...

  12. 33 CFR 1.08-1 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... criminal penalty procedures under subpart 1.07 of this part: (1) 46 CFR 25.05 whistles or other sound producing devices; (2) 33 CFR part 175, subpart B and 46 CFR subpart 25.25, Personal Flotation Devices. (3) 46 CFR 25.35 backfire flame control; (4) 46 CFR 25.40 ventilation; (5) 33 CFR part 173 numbering;...

  13. 45 CFR 1216.1-1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... NONDISPLACEMENT OF EMPLOYED WORKERS AND NONIMPAIRMENT OF CONTRACTS FOR SERVICE § 1216.1-1 Purpose. This part... otherwise be performed by employed workers and which will not supplant the hiring of, or result in the displacement of, employed workers or impair existing contracts for service. It implements section 404(a) of...

  14. 26 CFR 1.150-1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... certificate of indebtedness issued by the United States Treasury pursuant to the Demand Deposit State and Local Government Series program described in 31 CFR part 344. Working capital expenditure means any cost... TAXES (CONTINUED) Tax Exemption Requirements for State and Local Bonds § 1.150-1 Definitions. (a)...

  15. 26 CFR 1.150-1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... certificate of indebtedness issued by the United States Treasury pursuant to the Demand Deposit State and Local Government Series program described in 31 CFR part 344. Working capital expenditure means any cost... TAXES (CONTINUED) Tax Exemption Requirements for State and Local Bonds § 1.150-1 Definitions. (a)...

  16. 26 CFR 303.1-1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TAXES UNDER THE TRADING WITH THE ENEMY ACT § 303.1-1 Definitions. (a) General. When used in this part... Custodian whose functions were transferred to the Attorney General pursuant to Executive Order 9788 (3 CFR... the Enemy Act. The term “Trading With the Enemy Act” includes all amendments of such Act, and...

  17. 26 CFR 1.801-1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TAXES Life Insurance Companies § 1.801-1 Definitions. (a) Life insurance company. The term life... determining whether a company is a “life insurance company” within the meaning of that term as used in section... whether an insurance company is a life insurance company, the life insurance reserves (as defined......

  18. 26 CFR 1.508-1 - Notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... case of medical research organizations, 6 months after the date on which corrective and clarifying... (CONTINUED) Private Foundations § 1.508-1 Notices. (a) New organizations must notify the Commissioner that... subparagraph (3) of this paragraph, an organization that is organized after October 9, 1969, will not...

  19. Expect Surprises with 1-to-1 Laptops

    ERIC Educational Resources Information Center

    Tusch, Erich G.

    2012-01-01

    In 2004, prior to the launch of their 1-to-1 laptop program, the superintendent expressed some anxiety about the prospect of radically changing teaching and learning by issuing a laptop computer to every student and teacher. Although the concept was exciting, it carried big risks and would take time and thorough planning to execute well. Even with…

  20. 43 CFR 3191.1-1 - Petition.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) DELEGATION OF AUTHORITY, COOPERATIVE AGREEMENTS AND CONTRACTS FOR OIL AND GAS INSPECTION Delegation of Authority § 3191.1-1 Petition. The Governor or...

  1. 26 CFR 1.1083-1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exchanges in Obedience to S.e.c. Orders § 1.1083-1 Definitions. (a) Order of the... (52 Stat. 447)), and must be issued under the authority of section 11(b) or 11(e) of the...

  2. 26 CFR 1.1083-1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exchanges in Obedience to S.e.c. Orders § 1.1083-1 Definitions. (a) Order of the... (52 Stat. 447)), and must be issued under the authority of section 11(b) or 11(e) of the...

  3. EPA PMF 1.1 USER'S GUIDE

    EPA Science Inventory

    This user's manual is designed to guide a user through the use of the software EPA PMF 1.1 for a receptor modeling application. The manual covers details about what the user should do to operate the software, but it intentionally does not include guidance on how to interpret the...

  4. 26 CFR 1.1275-1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... rules regarding adjustments to adjusted issue price on a pro rata prepayment. (2) Bond issuance premium... States persons. (i) (j) Life annuity exception under section 1275(a)(1)(B)(i)—(1) Purpose. Section 1275(a... the contract and the contract depends (in whole or in substantial part) on the life expectancy of...

  5. 26 CFR 1.1275-1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... rules regarding adjustments to adjusted issue price on a pro rata prepayment. (2) Bond issuance premium... States persons. (i) (j) Life annuity exception under section 1275(a)(1)(B)(i)—(1) Purpose. Section 1275(a... the contract and the contract depends (in whole or in substantial part) on the life expectancy of...

  6. 26 CFR 1.1275-1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... rules regarding adjustments to adjusted issue price on a pro rata prepayment. (2) Bond issuance premium... States persons. (i) (j) Life annuity exception under section 1275(a)(1)(B)(i)—(1) Purpose. Section 1275(a... the contract and the contract depends (in whole or in substantial part) on the life expectancy of...

  7. [1+1+1] Cyclotrimerization for the Synthesis of Cyclopropanes

    PubMed Central

    Manna, Srimanta

    2016-01-01

    Abstract The synthesis of small rings by functionalization of C(sp3)−H bonds remains a great challenge. We report for the first time a copper‐catalyzed [1+1+1] cyclotrimerization of acetophenone derivatives under mild reaction conditions. The reaction has a broad scope for the stereoselective synthesis of cyclopropanes by trimerization of acetophenone. The developed transformation is based on an extraordinary copper‐catalyzed cascade process that allows saturated carbocycles to be obtained for the first time by cyclotrimerization through functionalization of C(sp3)−H bonds. The cascade of sixfold C(sp3)−H bond functionalization allows the synthesis of cyclopropanes in a highly stereoselective approach. PMID:26997466

  8. Douglas BTD-1 Destroyer

    NASA Technical Reports Server (NTRS)

    1945-01-01

    Douglas BTD-1 Destroyer: The single-seat Douglas BTD-1 Destroyer torpedo-bomber was developed from the two-seat XSB2D-1 scout-bomber. Although not put into full production, the BTD-1 lessons learned with the Destroyer were incorporated into the Douglas Skyraider's predecessor, the BT2D-1.

  9. Grumman JF-1 Duck

    NASA Technical Reports Server (NTRS)

    1934-01-01

    Grumman JF-1 Duck: The Grumman JF-1 Duck was in service with the NACA at Langley during the summer of 1934. The JF-1 was notably different from the later J2F Duck in that the JF-1 had a shorter central float. The NACA used the JF-1 in part as a propeller testbed aircraft.

  10. 1,1,1-trichloroethane: report of a fatal intoxication.

    PubMed

    Caplan, Y H; Backer, R C; Whitaker, J Q

    1976-01-01

    TCE was indicated in the accidental death of a woman cleaning up a paint spill in an enclosed, poorly ventilated room. Blood and tissue concentrations of TCE were measured by head-space gas chromatography. The concentrations found were compared with previously reported concentrations concluding that the demonstrable presence of TCE in blood at a concentration above 1.0 to 1.5 mg/100 ml would be consistent with death. However, the rapid dissipation of TCE from blood dictates that its presence in post mortem samples at any concentration must be considered as a factor in determining the cause of death. PMID:1277770

  11. IL-1 Blockade in Autoinflammatory Syndromes1

    PubMed Central

    Jesus, Adriana A.; Goldbach-Mansky, Raphaela

    2014-01-01

    Monogenic autoinflammatory syndromes present with excessive systemic inflammation including fever, rashes, arthritis, and organ-specific inflammation and are caused by defects in single genes encoding proteins that regulate innate inflammatory pathways. Pathogenic variants in two interleukin-1 (IL-1)–regulating genes, NLRP3 and IL1RN, cause two severe and early-onset autoinflammatory syndromes, CAPS (cryopyrin associated periodic syndromes) and DIRA (deficiency of IL-1 receptor antagonist). The discovery of the mutations that cause CAPS and DIRA led to clinical and basic research that uncovered the key role of IL-1 in an extended spectrum of immune dysregulatory conditions. NLRP3 encodes cryopyrin, an intracellular “molecular sensor” that forms a multimolecular platform, the NLRP3 inflammasome, which links “danger recognition” to the activation of the proinflammatory cytokine IL-1β. The success and safety profile of drugs targeting IL-1 in the treatment of CAPS and DIRA have encouraged their wider use in other autoinflammatory syndromes including the classic hereditary periodic fever syndromes (familial Mediterranean fever, TNF receptor–associated periodic syndrome, and hyperimmunoglobulinemia D with periodic fever syndrome) and additional immune dysregulatory conditions that are not genetically well defined, including Still’s, Behcet’s, and Schnitzler diseases. The fact that the accumulation of metabolic substrates such as monosodium urate, ceramide, cholesterol, and glucose can trigger the NLRP3 inflammasome connects metabolic stress to IL-1β-mediated inflammation and provides a rationale for therapeutically targeting IL-1 in prevalent diseases such as gout, diabetes mellitus, and coronary artery disease. PMID:24422572

  12. Alpha-1 Antitrypsin Deficiency

    MedlinePlus

    ... from the NHLBI on Twitter. What Is Alpha-1 Antitrypsin Deficiency? Alpha-1 antitrypsin (an-tee-TRIP-sin) deficiency, or AAT ... as it relates to lung disease. Overview Alpha-1 antitrypsin, also called AAT, is a protein made ...

  13. High Resolution 4.7 Micron Keck/NIRSPEC Spectra of Protostars. 1; Ices and Infalling Gas in the Disk of L1489 IRS

    NASA Technical Reports Server (NTRS)

    Boogert, A. C. A.; Hogerheijde, M. R.; Blake, G. A.

    2001-01-01

    We explore the infrared M band (4.7 micron) spectrum of the class I protostar L1489 IRS in the Taurus Molecular Cloud. This is the highest resolution wide coverage spectrum at this wavelength of a low mass protostar observed to date (R =25,000; (Delta)v =12 km s(exp -1). A large number of narrow absorption lines of gas phase (12)CO, (13)CO, and C(sup 18)O are detected, as well as a prominent band of solid (12)CO. The gas phase (12)CO lines have red shifted absorption wings (up to 100 km s(exp -1)), which likely originate from warm disk material falling toward the central object. Both the isotopes and the extent of the (12)CO line wings are successfully fitted with a contracting disk model of this evolutionary transitional object. This shows that the inward motions seen in millimeter wave emission lines continue to within approx. 0.1 AU from the star. The amount of high velocity infalling gas is however overestimated by this model, suggesting that only part of the disk is infalling, e.g. a hot surface layer or hot gas in magnetic field tubes. The colder parts of the disk are traced by the prominent CO ice band. The band profile results from CO in 'polar' ices (CO mixed with H2O), and CO in 'apolar' ices. At the high spectral resolution, the 'apolar' component is, for the first time, resolved into two distinct components, likely due to pure CO and CO mixed with CO2, O2 and/or N2. The ices have probably experienced thermal processing in the upper disk layer traced by our pencil absorption beam: much of the volatile 'apolar' ices has evaporated, the depletion factor of CO onto grains is remarkably low (approx. 7%), and the CO2 traced in the CO band profile was possibly formed energetically. This study shows that high spectral resolution 4.7 micron observations provide important and unique information on the dynamics and structure of protostellar disks and the origin and evolution of ices in these disks.

  14. SPARK Version 1. 1 user manual

    SciTech Connect

    Weissenburger, D.W.

    1988-01-01

    This manual describes the input required to use Version 1.1 of the SPARK computer code. SPARK 1.1 is a library of FORTRAN main programs and subprograms designed to calculate eddy currents on conducting surfaces where current flow is assumed zero in the direction normal to the surface. Surfaces are modeled with triangular and/or quadrilateral elements. Lorentz forces produced by the interaction of eddy currents with background magnetic fields can be output at element nodes in a form compatible with most structural analysis codes. In addition, magnetic fields due to eddy currents can be determined at points off the surface. Version 1.1 features eddy current streamline plotting with optional hidden-surface-removal graphics and topological enhancements that allow essentially any orientable surface to be modeled. SPARK also has extensive symmetry specification options. In order to make the manual as self-contained as possible, six appendices are included that present summaries of the symmetry options, topological options, coil options and code algorithms, with input and output examples. An edition of SPARK 1.1 is available on the Cray computers at the National Magnetic Fusion Energy Computer Center at Livermore, California. Another more generic edition is operational on the VAX computers at the Princeton Plasma Physics Laboratory and is available on magnetic tape by request. The generic edition requires either the GKS or PLOT10 graphics package and the IMSL or NAG mathematical package. Requests from outside the United States will be subject to applicable federal regulations regarding dissemination of computer programs. 22 refs.

  15. Geometric modeling of homoepitaxial CVD diamond growth: I. The {1 0 0}{1 1 1}{1 1 0}{1 1 3} system

    NASA Astrophysics Data System (ADS)

    Silva, F.; Bonnin, X.; Achard, J.; Brinza, O.; Michau, A.; Gicquel, A.

    2008-01-01

    Plasma-assisted CVD homoepitaxial diamond growth is a process that must satisfy many stringent requirements to meet industrial applications, particularly in high-power electronics. Purity control and crystalline quality of the obtained samples are of paramount importance and their optimization is a subject of active research. In the process of such studies, we have obtained high purity CVD diamond monocrystals with unusual morphologies, namely with apparent {1 1 3} stable faces. This phenomenon has led us to examine the process of CVD diamond growth and build up a 3D geometrical model, presented here, describing the film growth as a function of time. The model has been able to successfully describe the morphology of our obtained crystals and can be used as a predictive tool to predetermine the shape and size of a diamond crystal grown in a given process configuration. This renders accessible control of desirable properties such as largest usable diamond surface area and/or film thickness, before the cutting and polishing manufacture steps take place. The two latter steps are more sensitive to the geometry of the growth sectors, which will be addressed in a companion paper. Our model, applicable to the growth of any cubic lattice material, establishes a complete mapping of the final morphology state of growing diamond, as a function of the growth rates of the crystalline planes considered, namely {1 0 0}, {1 1 1}, {1 1 0}, and {1 1 3} planes, all of which have been observed experimentally in diamond films. The model makes no claim as to the stability of the obtained faces, such as the occurrence of non-epitaxial crystallites or twinning. It is also possible to deduce transient behavior of the crystal morphology as growth time is increased. The model conclusions are presented in the form of a series of diagrams, which trace the existence (and dominance) boundaries of each face type, in presence of the others, and where each boundary crossing represent a topology

  16. 1; '" ~i.im~

    Center for Drug Evaluation (CDER)

    ... t ~ .. I:~ ~, r1 " )íJ .( l\\ ,# f ~ .; , r 1I1§~.OGlP.~.mi .. !II .. 0 . .... t- !!,. i:qrzrr -19~,i;!;¡ $ i'' is il Il '\\ii II ~ w "' =~ &2L;;&Æ__ II .. i: Ci.)ill.ii.iill~~~1I ~ . . .. ...

  17. Cold Sores (HSV-1)

    MedlinePlus

    ... Help a Friend Who Cuts? Cold Sores (HSV-1) KidsHealth > For Teens > Cold Sores (HSV-1) Print A A A Text Size What's in ... person's lips, are caused by herpes simplex virus-1 (HSV-1) . But they don't just show ...

  18. New fluorinated agonists for targeting the sphingosin-1-phosphate receptor 1 (S1P(1)).

    PubMed

    Shaikh, Rizwan S; Keul, Petra; Schäfers, Michael; Levkau, Bodo; Haufe, Günter

    2015-11-15

    The sphingosine-1-phosphate receptor type 1 (S1P1) is involved in fundamental biological processes such as regulation of immune cell trafficking, vascular barrier function and angiogenesis. This Letter presents multistep syntheses of various fluorine substituted 12-aryl analogues of the drug fingolimod (FTY720) and a seven-steps route to 2-amino-17,17-difluoro-2-(hydroxymethyl)heptadecan-1-ol. In vitro and in vivo tests proved all these compounds as potent S1P1 receptor agonists.

  19. Cardiomyopathy from 1,1-Difluoroethane Inhalation.

    PubMed

    Kumar, Suwen; Joginpally, Tejaswini; Kim, David; Yadava, Mrinal; Norgais, Konchok; Laird-Fick, Heather S

    2016-10-01

    Consumer aerosol products can be inhaled for their psychoactive effects, but with attendant adverse health effects including "sudden sniffing death." Cardiomyopathy has rarely been described in association with 1,1-difluoroethane (DFE), a common aerosol propellant. We report a 33-year-old male who developed acute myocardial injury and global hypokinesis along with rhabdomyolysis, acute kidney injury, and fulminant hepatitis after 2 days' nearly continuous huffing. Workup for other causes, including underlying coronary artery disease, was negative. His cardiac function improved over time. The exact mechanism of DFE's effects is uncertain but may include catecholamine-induced cardiomyopathy, coronary vasospasm, or direct cellular toxicity.

  20. Cardiomyopathy from 1,1-Difluoroethane Inhalation.

    PubMed

    Kumar, Suwen; Joginpally, Tejaswini; Kim, David; Yadava, Mrinal; Norgais, Konchok; Laird-Fick, Heather S

    2016-10-01

    Consumer aerosol products can be inhaled for their psychoactive effects, but with attendant adverse health effects including "sudden sniffing death." Cardiomyopathy has rarely been described in association with 1,1-difluoroethane (DFE), a common aerosol propellant. We report a 33-year-old male who developed acute myocardial injury and global hypokinesis along with rhabdomyolysis, acute kidney injury, and fulminant hepatitis after 2 days' nearly continuous huffing. Workup for other causes, including underlying coronary artery disease, was negative. His cardiac function improved over time. The exact mechanism of DFE's effects is uncertain but may include catecholamine-induced cardiomyopathy, coronary vasospasm, or direct cellular toxicity. PMID:26613951

  1. 26 CFR 1.1083-1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Corporation subject to a mortgage of $100,000. (2) Short-term obligations (including notes, drafts, bills of... nonexempt property within the meaning of section 1083(e) (1), (2), or (3). (5) Money, and the right to... section 1083 (e) (2) or (3). The term the right to receive money includes, among other items,...

  2. 14 CFR 1.1 - General definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... by the dynamic reaction of the air against its wings. Airport means an area of land or water that is... that is producible from sea level to an established higher altitude. Amateur rocket means an unmanned rocket that: (1) Is propelled by a motor or motors having a combined total impulse of 889,600...

  3. 14 CFR 1.1 - General definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... by the dynamic reaction of the air against its wings. Airport means an area of land or water that is... that is producible from sea level to an established higher altitude. Amateur rocket means an unmanned rocket that: (1) Is propelled by a motor or motors having a combined total impulse of 889,600...

  4. 14 CFR 1.1 - General definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... by the dynamic reaction of the air against its wings. Airport means an area of land or water that is... that is producible from sea level to an established higher altitude. Amateur rocket means an unmanned rocket that: (1) Is propelled by a motor or motors having a combined total impulse of 889,600...

  5. 26 CFR 1.165-1 - Losses.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... basis of $10,000 is completely destroyed by fire in 1961, and if the taxpayer's only claim for... the loss (see § 1.165-8, relating to theft losses). However, if in the year of discovery there exists... not incurred in any transaction entered into for profit, if such losses arise from fire,...

  6. 26 CFR 1.508-1 - Notices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... them, under section 508, see the special rules under § 1.170A-9(e). (vi) A foreign organization shall... March 22, 1973, whichever comes later. See paragraph (a)(2)(iii) of this section, for rules pertaining... Form 4653 need be completed only if the organization is, or thinks it might be, described in...

  7. LOX-1 transcription.

    PubMed

    Hermonat, Paul L; Zhu, Hongqing; Cao, Maohua; Mehta, Jawahar L

    2011-10-01

    The importance of the lectin-like oxidized LDL receptor (LOX-1) gene in cardiovascular and other diseases is slowly being revealed. LOX-1 gene expression appears to be a "canary in a coal mine" for atherogenesis, being strongly up-regulated early on in a number of cell types when they are activated, and predicting the sites of future disease. From this early time point the LOX-1 protein often participates in the disease process itself. While gene/protein expression can be regulated on a multiplicity of levels, the most basic and important mode of regulation is usually transcriptional. There are very few studies on the transcriptional regulation of the human LOX-1 promoter; fewer still on definitive mapping of the transcription factors involved. It is known that a wide variety of stimuli up-regulate LOX-1, usually/probably on the transcriptional level. Angiotensin II (Ang II) is one important regulator of renin-angiotensin system and stimulator LOX-1. Ang II is known to up-regulate LOX-1 transcription through an NF-kB motif located at nt -2158. Oxidized low density lipoprotein (ox-LDL) is another important cardiovascular regulator, particularly of atherosclerotic disease, and a strong stimulator of LOX-1. Ox-LDL is known to up-regulate LOX-1 transcription through an Oct-1 motif located at nt -1556. The subsequent enhanced LOX-1 receptor numbers and their binding by ox-LDL ligand triggers a positive feedback loop, increasing further LOX-1 expression, with a presently unknown regulatory governor. The Oct-1 gene also has its own Oct-1-driven positive feedback loop, which likely also contributes to LOX-1 up-regulation. There is also data which suggests the involvement of the transcription factor AP-1 during stimulation with Phorbol 12-myristate acetate. While the importance of NF-κB as a transcriptional regulator of cardiovascular-relevant genes is well known, the importance of Oct-1 is not. Data suggests that Oct-1-mediated up-regulation of transcription is an early

  8. Alpha-1 Antitrypsin Test

    MedlinePlus

    ... measures the level of the protein AAT in blood. Alpha-1 antitrypsin phenotype testing evaluates the amount and type of AAT being produced and compares it to normal patterns. Alpha-1 antitrypsin genotype testing ( DNA testing) can ...

  9. Alpha-1 antitrypsin test

    MedlinePlus

    ... page: //medlineplus.gov/ency/article/003715.htm Alpha-1 antitrypsin test To use the sharing features on this page, please enable JavaScript. Alpha-1 antitrypsin is a laboratory test to measure the ...

  10. CCF Experiment #1

    NASA Video Gallery

    Images from CCF camera during Experiment #1, or EU#1, square groove geometry operations. The free surface, or gas/liquid interface, assumes a curved shape under subcritical flow conditions as its m...

  11. MIL1A

    Atmospheric Science Data Center

    2014-09-03

    ... MISR Level 1A camera charge-coupled device (CCD) Science Data: Reformatted Annotated Level 1A product of the CCD science data. ... Files:  Processing Status Production Report Read Software Files :  Data Product ...

  12. A1C test

    MedlinePlus

    HbA1C test; Glycated hemoglobin test; Glycosylated hemoglobin test; Hemoglobin glycosylated test; Glycohemoglobin test ... have recently eaten does not affect the A1C test, so you do not need to fast to ...

  13. RAP1GA1: A candidate tumor suppressor locus in 1p36.1

    SciTech Connect

    Ranade, K.; Hussussian, C.J.; Higgins, P.

    1994-09-01

    The rap1/Krev-1 gene (RAP1A) encodes a p21-related protein that suppresses transformation by activated p21{sup ras}. The GTPase activating protein (GAP) gene for p21{sup rap1A} (RAP1GA1) has recently been assigned to chromosome 1p36.1-p35, a region of the genome that is frequently involved in deletions and rearrangements in several different tumors including breast, colon and hepatocellular carcinomas, melanoma, and neuroblastoma. GAP genes negatively regulate the activity of p21 proteins by catalyzing the conversion of the active GTP-bound forms to the inactive GDP-bound forms. The physiological function of p21{sup rap1A}-GAP makes it a strong candidate as a tumor suppressor gene that may have a role in the development of one or more of these malignancies. We have refined the localization of RAP1GA1 by linkage analysis with a highly informative (CA){sub n} repeat contained within the gene, and demonstrated that it is within the minimal deleted region for breast and colon carcinomas, and that it is excluded from the minimally deleted region in melanoma and neuroblastoma. Genetic mapping in the mouse demonstrated that Rap1ga1 is located {approximately}10 cM proximal to Pnd and therefore maps within the interval containing the modifier of Min gene (Mom-1) and the plasmocytoma susceptibility locus (Pcts). The human RAP1GA1 gene contains at least 27 exons. The coding region contains 22 exons, and there are at least five 5{prime}-UT exons that are assembled in a complex pattern of alternative splicing in different tissues. The localization of RAP1GA1 makes it a very strong candidate for a role as a modifier gene involved in the common secondary abnormalities involving 1p36 in several different carcinomas. The potential role of RAP1GA1 in these malignancies is currently being investigated by sequence analysis of breast and colon carcinomas with loss of heterozygosity in 1p36.

  14. α1-Antitrypsin Deficiency.

    PubMed

    Hatipoğlu, Umur; Stoller, James K

    2016-09-01

    α1-Antitrypsin deficiency is an autosomal codominant condition that predisposes to emphysema and cirrhosis. The condition is common but grossly under-recognized. Identifying patients' α1-antitrypsin deficiency has important management implications (ie, smoking cessation, genetic and occupational counseling, and specific treatment with the infusion of pooled human plasma α1-antitrypsin). The weight of evidence suggests that augmentation therapy slows the progression of emphysema in individuals with severe α1-antitrypsin deficiency. PMID:27514595

  15. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101830, and TBD).

  16. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830).

  17. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. A larger image is available without labels (No. 0101755).

  18. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This computer-generated image depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830, and TBD).

  19. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This scale model depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830, and TBD). This image is from a digital still camera; higher resolution is not available.

  20. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This scale model depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, 0101830, and TBD).

  1. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This scale model depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Here the transparent furnace is extracted for servicing. Key elements are labeled in other images (0101754, 0101829, 0101830, and TBD).

  2. Materials Science Research Rack-1 (MSRR-1)

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This scale model depicts the Materials Science Research Rack-1 (MSRR-1) being developed by NASA's Marshall Space Flight Center and the European Space Agency (ESA) for placement in the Destiny laboratory module aboard the International Space Station. The rack is part of the plarned Materials Science Research Facility (MSRF) and is expected to include two furnace module inserts, a Quench Module Insert (being developed by NASA's Marshall Space Flight Center) to study directional solidification in rapidly cooled alloys and a Diffusion Module Insert (being developed by the European Space Agency) to study crystal growth, and a transparent furnace (being developed by NASA's Space Product Development program). Multi-user equipment in the rack is being developed under the auspices of NASA's Office of Biological and Physical Research (OBPR) and ESA. Key elements are labeled in other images (0101754, 0101829, and TBD). This composite is from a digital still camera; higher resolution is not available.

  3. Microhydropower Handbook, Volume 1, Part 1

    SciTech Connect

    McKinney, J.D.

    1983-01-01

    The purpose of the “Microhydropower Handbook, Volume 1, Part 1” is to provide a mechanically proficient lay person with sufficient information to evaluate microhydropower site potential, lay out a site, select and install equipment, and finally, operate and maintain the completed system. The actual construction details of the site are not included; rather, pointers are given as to what help an individual should expect from a construction contractor, and general guidelines on construction details are provided. In addition, information about obtaining financing and permits is provided. To help offset cost, the person performing the work, referred to as the “developer,” is encouraged to do as much of the work as possible. However, developers with major areas of uncertainty should consider professional assistance.

  4. Psychoneuroimmunology and HIV-1.

    ERIC Educational Resources Information Center

    Antoni, Michael H.; And Others

    1990-01-01

    Presents evidence describing benefits of behavioral interventions such as aerobic exercise training on both psychological and immunological functioning among high risk human immunodeficiency virus-Type 1 (HIV-1) seronegative and very early stage seropositive homosexual men. HIV-1 infection is cast as chronic disease for which early…

  5. MI1ANAV

    Atmospheric Science Data Center

    2014-09-03

    MI1ANAV MISR Level 1A Navigation Data: Reformatted Annotated Level 1A Product for the Navigation Data, which contains samples of the Terra Platform position and ... Specification Versioning History:  Engineering, Navigation SCAR-B Block:  SCAR-B ...

  6. Horizontally separated 1-in-1 crossing insertions

    SciTech Connect

    Syphers, M.J.

    1985-10-01

    Previous to this workshop, realistic lattices have been developed for vertically separated l-in-l (e.g., D.E. Johnson, A.A. Garren) and 2-in-1 (e.g., S. Heifets) magnets as well as for horizontally separated 2-in-l magnets (e.g., SSC RDS). Bringing together the widely separated ({approximately}60-70 cm) beams in a reasonable length of tunnel and keeping the dispersion zero at the interaction point has been difficult in the vertical l-in-l case. Most designs have required spacial 2-in-1 quadrupoles near the interaction point where the beams are separated by 15 cm or less. It is not clear that such magnets, as dictated by some of these lattice designs, can easily be built. The purpose of this exercise is to provide a crossing insertion for a realistic lattice which involves horizontally separated l-in-l magnets. The following horizontal crossing insertions, which incorporate the dispersion suppressors and phase trombones into the major arcs, need no special 2-in-1 magnets near the interaction point. The dispersion at the IP created by the horizontal crossing can be cancelled by the dispersion suppressor and one set of triplets.

  7. Melaminium nitrate–melamine–water (1/1/1)

    PubMed Central

    Adam, Farook; Lin, Sek Kei; Hello, Kasim Mohammed; Hemamalini, Madhukar; Fun, Hoong-Kun

    2010-01-01

    In the crystal structure of the title salt, C3H7N6 +·NO3 −·C3H6N6·H2O, the asymmetric unit consists of two neutral melamine (1,3,5-triazine-2,4,6-triamine) mol­ecules, two melaminium cations, two nitrate anions and two solvent water mol­ecules. One of the nitrate anions is disordered over two sets of positions, with a refined occupancy ratio of 0.909 (3):0.091 (3). The cations and neutral mol­ecules are approximately planar, with maximum deviations of 0.018 (2), 0.024 (2), 0.019 (2) and 0.007 (2) Å for each, respectively. In the crystal structure, melaminium cations and netural melamine mol­ecules self-assemble via N—H⋯N hydrogen bonds to form a supra­molecular hexa­gonal-shaped motif. In addition, the nitrate anions and water mol­ecules are connected by N—H⋯O hydrogen bonds to form a three-dimensional network. PMID:21589188

  8. The E1 proteins

    SciTech Connect

    Bergvall, Monika; Melendy, Thomas; Archambault, Jacques

    2013-10-15

    E1, an ATP-dependent DNA helicase, is the only enzyme encoded by papillomaviruses (PVs). It is essential for replication and amplification of the viral episome in the nucleus of infected cells. To do so, E1 assembles into a double-hexamer at the viral origin, unwinds DNA at the origin and ahead of the replication fork and interacts with cellular DNA replication factors. Biochemical and structural studies have revealed the assembly pathway of E1 at the origin and how the enzyme unwinds DNA using a spiral escalator mechanism. E1 is tightly regulated in vivo, in particular by post-translational modifications that restrict its accumulation in the nucleus. Here we review how different functional domains of E1 orchestrate viral DNA replication, with an emphasis on their interactions with substrate DNA, host DNA replication factors and modifying enzymes. These studies have made E1 one of the best characterized helicases and provided unique insights on how PVs usurp different host-cell machineries to replicate and amplify their genome in a tightly controlled manner. - Highlights: • The papillomavirus E1 helicase orchestrates replication of the viral DNA genome. • E1 assembles into a double-hexamer at the viral origin with the help of E2. • E1 interacts with cellular DNA replication factors. • E1 unwinds DNA using a spiral escalator mechanism. • Nuclear accumulation of E1 is regulated by post-translational modifications.

  9. First images of a possible CO(+)-tail of comet P/Schwassmann-Wachmann 1 observed against the dust coma background

    NASA Technical Reports Server (NTRS)

    Jockers, Klaus; Bonev, T.; Ivanova, Violeta; Rauer, H.

    1992-01-01

    Comet P/Schwassmann-Wachmann 1 was observed with the 2m-Ritchey-Cretien Telescope of the Bulgarian National Observatory, Rozhen, Bulgaria, using the CCD-camera and focal reducer of the Max-Planck-Institute for Aeronomy. Images were taken in a red continuum window and in the 2-0 A(exp 2)Pi - X(exp 2)Sigma(+) band of CO(+) located in the blue part of the spectrum. The red images reveal an extended dust coma. From a comparison of the red and blue images a dust reddening of 13.2 percent per 1000 A is derived. At 642 nm the magnitude of the comet with a square diaphragm of 4.5 arcsec is 16.6. The blue images, taken in the CO(+) band, show a significantly different brightness distribution which is interpreted as presence of a CO(+) coma and tail superimposed on the continuum. A column density of several 10(exp 10) CO(+) molecules cm(exp -2) is derived. The tail thickness of 10(exp 5) km is unexpectedly small. We estimate the CO(+) production rate to about 6 x 10(exp 26) CO(+) particles s(exp -1). This value does not support the idea that the outbursts of this comet are caused by crystallization of amorphous water ice.

  10. [DAX-1 abnormality].

    PubMed

    Kinoshita, Ei-ichi

    2002-02-01

    DAX-1 is an orphan nuclear receptor that plays a key role in the development and function of the adrenal gland and hypothalamic-pituitary-gonadal axis. Absence of DAX-1 results in X-linked adrenal hypoplasia congenita, a human inherited disorder characterized by adrenal insufficiency and hypogonadotropic hypogonadism. The DAX-1 gene may be responsible for a male-to-female sex reversal syndrome, referred to as dosage sensitive sex reversal(DSS), due to the duplication of a small region of human chromosome Xp21. Dax-1 and Sry have been shown to act antagonistically in the mouse system, where over-expression of Dax-1 leads to female development and increasing activity of Sry to male development. Although these data strongly implicate Dax-1 in sex determination, there is no evidence that DAX-1 is equivalent to DSS in human.

  11. Prokineticin1 and pregnancy.

    PubMed

    Alfaidy, Nadia

    2016-06-01

    Prokineticin 1 (PROK1), also called EG-VEGF, is a peptide of 86 amino acids with multiple biological functions. PROK1 acts via two G-protein coupled receptors: PROKR1 PROKR2. PROK1 is highly expressed in the placenta. This article reports the expression and the role of PROK1 during normal and pathological pregnancies: (i) during early pregnancy, PROK1 exhibits a peak of placental expression shortly before the establishment of the feto-maternal circulation; (ii) its receptors, PROKR1 PROKR2 are highly expressed in human placenta; (iii) its expression is increased by hypoxia; (iv) PROK1 inhibits extravillous trophoblasts migration and invasion and increases their proliferation and survival; (v) PROK1 is also a pro-angiogenic placental factor that increases microvascular placental endothelial cells proliferation, migration, invasion, and permeability. Circulating PROK1 levels are five times higher in pregnant women during the first trimester compared to the second and third trimesters. Also, its serum levels are higher in patients with preeclampsia (PE) and in patients with isolated intra-uterine growth restriction (IUGR). In mice, maintaining high level of PROK1 beyond its normal period of production (>10.5dpc) reproduces symptoms of PE. To date, our results demonstrated that PROK1 is a central factor of human placentation with direct roles both in the control of trophoblast invasion and villous growth. Thus, a failure in the expression of PROK1 and/or its receptor during pregnancy may contribute to the development of PE and/or IUGR. Besides theses original findings, we also report a direct role of this factor in parturition. PMID:27172869

  12. SAF1. Standard Agent Framework 1

    SciTech Connect

    Goldsmith, S.Y

    1997-06-01

    The Standard Agent framework provides an extensible object-oriented development environment suitable for use in both research and applications projects. The SAF provides a means for constructing and customizing multi-agent systems through specialization of standard base classes (architecture-driven framework) and by composition of component classes (data driven framework). The standard agent system is implemented as an extensible object-centerd framework. Four concrete base classes are developed: (1) Standard Agency; (2) Standard Agent; (3) Human Factor, and (4) Resources. The object-centered framework developed and utilized provides the best comprimise between generality and flexibility available in agent development systems today.

  13. α1-Antitrypsin deficiency.

    PubMed

    Greene, Catherine M; Marciniak, Stefan J; Teckman, Jeffrey; Ferrarotti, Ilaria; Brantly, Mark L; Lomas, David A; Stoller, James K; McElvaney, Noel G

    2016-01-01

    α1-Antitrypsin deficiency (A1ATD) is an inherited disorder caused by mutations in SERPINA1, leading to liver and lung disease. It is not a rare disorder but frequently goes underdiagnosed or misdiagnosed as asthma, chronic obstructive pulmonary disease (COPD) or cryptogenic liver disease. The most frequent disease-associated mutations include the S allele and the Z allele of SERPINA1, which lead to the accumulation of misfolded α1-antitrypsin in hepatocytes, endoplasmic reticulum stress, low circulating levels of α1-antitrypsin and liver disease. Currently, there is no cure for severe liver disease and the only management option is liver transplantation when liver failure is life-threatening. A1ATD-associated lung disease predominately occurs in adults and is caused principally by inadequate protease inhibition. Treatment of A1ATD-associated lung disease includes standard therapies that are also used for the treatment of COPD, in addition to the use of augmentation therapy (that is, infusions of human plasma-derived, purified α1-antitrypsin). New therapies that target the misfolded α1-antitrypsin or attempt to correct the underlying genetic mutation are currently under development. PMID:27465791

  14. The NLRP1 inflammasomes.

    PubMed

    Chavarría-Smith, Joseph; Vance, Russell E

    2015-05-01

    Inflammasomes are cytosolic protein complexes that serve as platforms for the recruitment and activation of the pro-inflammatory CASPASE-1 protease. CASPASE-1 activation leads to processing and maturation of the cytokines interleukin-1β and interleukin-18 and a lytic form of cell death termed pyroptosis. Inflammasome assembly is initiated by cytosolic sensors in response to microbial infections. Many of these sensors, including NLRP1 (NLR family, pyrin domain containing 1), are described to form an inflammasome, but until recently, the mechanism of inflammasome activation and its physiological functions in host defense have remained unclear. In the last few years, important advances in our understanding of NLRP1 biology have been achieved. In this review, we discuss the activation of NLRP1 by various stimuli, including Bacillus anthracis lethal toxin, Toxoplasma gondii, muramyl dipeptide, and host intracellular ATP depletion. The role NLRP1 plays in pathogen recognition and resistance during infection is also discussed, as is the regulation of NLRP1 by host and viral proteins. We conclude by discussing the unexpected differences in the mechanism of NLRP1 inflammasome activation, as compared to the activation of other inflammasomes, such as the NAIP (NLR family, apoptosis inhibitory protein)/NLRC4 inflammasomes. PMID:25879281

  15. Electronic structure of octane on Cu(1 1 1) and Ni(1 1 1) studied by near edge X-ray absorption fine structure

    NASA Astrophysics Data System (ADS)

    Kiguchi, Manabu; Entani, Shiro; Ikeda, Susumu; Yoshikawa, Genki; Nakai, Ikuyo; Kondoh, Hiroshi; Ohta, Toshiaki; Saiki, Koichiro

    2007-09-01

    The electronic structure of an octane film grown on Cu(1 1 1) and Ni(1 1 1) was studied using C K-edge near edge X-ray absorption fine structure (NEXAFS). A pre-peak was observed on the bulk edge onset for the 1 ML thick octane films on the metal substrates. The pre-peak originated from metal induced gap states (MIGS) in the band gap of octane. The intensity of the pre-peak for octane/Ni(1 1 1) was the same as that of octane/Cu(1 1 1), suggesting that there was little difference in the density of unoccupied MIGS between the octane film on Ni(1 1 1) and Cu(1 1 1). We discuss the metal dependence of the density of unoccupied MIGS on the band structure of the metals.

  16. Event generation with SHERPA 1.1

    SciTech Connect

    Gleisberg, T.; Hoche, Stefan.; Krauss, F.; Schoenherr, M.; Schumann, S.; Siegert, F.; Winter, J.

    2008-12-18

    In this paper the current release of the Monte Carlo event generator Sherpa, version 1.1, is presented. Sherpa is a general-purpose tool for the simulation of particle collisions at high-energy colliders. It contains a very flexible tree-level matrix-element generator for the calculation of hard scattering processes within the Standard Model and various new physics models. The emission of additional QCD partons off the initial and final states is described through a parton-shower model. To consistently combine multi-parton matrix elements with the QCD parton cascades the approach of Catani, Krauss, Kuhn and Webber is employed. A simple model of multiple interactions is used to account for underlying events in hadron-hadron collisions. The fragmentation of partons into primary hadrons is described using a phenomenological cluster-hadronization model. A comprehensive library for simulating tau-lepton and hadron decays is provided. Where available form-factor models and matrix elements are used, allowing for the inclusion of spin correlations; effects of virtual and real QED corrections are included using the approach of Yennie, Frautschi and Suura.

  17. Pandemic H1N1 influenza

    PubMed Central

    Kumar, Anand

    2011-01-01

    The 2009 H1N1 influenza A virus that has targeted not only those with chronic medical illness, the very young and old, but also a large segment of the patient population that has previously been afforded relative protection - those who are young, generally healthy, and immune naive. The illness is mild in most, but results in hospitalization and severe ARDS in an important minority. Among those who become critically ill, 20-40% will die, predominantly of severe hypoxic respiratory failure. However, and potentially in part due to the young age of those affected, intensive care with aggressive oxygenation support will allow most people to recover. The volume of patients infected and with critical illness placed substantial strain on the capacity of the health care system and critical care most specifically. Despite this, the 2009 pandemic has engaged our specialty and highlighted its importance like no other. Thus far, the national and global critical care response has been brisk, collaborative and helpful - not only for this pandemic, but for subsequent challenges in years ahead. PMID:22263101

  18. X-1 in flight

    NASA Technical Reports Server (NTRS)

    1947-01-01

    The Bell Aircraft Corporation X-1-1 (#46-062) in flight. The shock wave pattern in the exhaust plume is visible. The X-1 series aircraft were air-launched from a modified Boeing B-29 or a B-50 Superfortress bombers. The X-1-1 was painted a bright orange by Bell Aircraft. It was thought that the aircraft would be more visable to those doing the tracking during a flight. When NACA received the airplanes they were painted white, which was an easier color to find in the skies over Muroc Air Field in California. This particular craft was nicknamed 'Glamorous Glennis' by Chuck Yeager in honor of his wife, and is now on permanent display in the Smithsonian Institution's National Air and Space Museum in Washington, DC. There were five versions of the Bell X-1 rocket-powered research aircraft that flew at the NACA High-Speed Flight Research Station, Edwards, California. The bullet-shaped X-1 aircraft were built by Bell Aircraft Corporation, Buffalo, N.Y. for the U.S. Army Air Forces (after 1947, U.S. Air Force) and the National Advisory Committee for Aeronautics (NACA). The X-1 Program was originally designated the XS-1 for EXperimental Sonic. The X-1's mission was to investigate the transonic speed range (speeds from just below to just above the speed of sound) and, if possible, to break the 'sound barrier.' Three different X-1s were built and designated: X-1-1, X-1-2 (later modified to become the X-1E), and X-1-3. The basic X-1 aircraft were flown by a large number of different pilots from 1946 to 1951. The X-1 Program not only proved that humans could go beyond the speed of sound, it reinforced the understanding that technological barriers could be overcome. The X-1s pioneered many structural and aerodynamic advances including extremely thin, yet extremely strong wing sections; supersonic fuselage configurations; control system requirements; powerplant compatibility; and cockpit environments. The X-1 aircraft were the first transonic-capable aircraft to use an all

  19. 26 CFR 1.1-2 - Limitation on tax.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Limitation on tax. 1.1-2 Section 1.1-2 Internal... Surtaxes § 1.1-2 Limitation on tax. (a) Taxable years ending before January 1, 1971. For taxable years ending before January 1, 1971, the tax imposed by section 1 (whether by subsection (a) or subsection...

  20. 26 CFR 1.1-2 - Limitation on tax.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Limitation on tax. 1.1-2 Section 1.1-2 Internal... Surtaxes § 1.1-2 Limitation on tax. (a) Taxable years ending before January 1, 1971. For taxable years ending before January 1, 1971, the tax imposed by section 1 (whether by subsection (a) or subsection...

  1. 26 CFR 1.1-2 - Limitation on tax.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Limitation on tax. 1.1-2 Section 1.1-2 Internal... Surtaxes § 1.1-2 Limitation on tax. (a) Taxable years ending before January 1, 1971. For taxable years ending before January 1, 1971, the tax imposed by section 1 (whether by subsection (a) or subsection...

  2. X-1 on display

    NASA Technical Reports Server (NTRS)

    1949-01-01

    A Bell Aircraft Corporation X-1 series aircraft on display at an Open House at NACA Muroc Flight Test Unit or High-Speed Flight Research Station hangar on South Base of Edwards Air Force Base, California. (The precise date of the photo is uncertain, but it is probably before 1948.) The instrumentation that was carried aboard the aircraft to gather data is on display. The aircraft data was recorded on oscillograph film that was read, calibrated, and converted into meaningful parameters for the engineers to evaluate from each research flight. In the background of the photo are several early U.S. jets. These include several Lockheed P-80 Shooting Stars, which were used as chase planes on X-1 flights; two Bell P-59 Airacomets, the first U.S. jet pursuit aircraft (fighter in later parlance); and a prototype Republic XP-84 Thunderjet. There were five versions of the Bell X-1 rocket-powered research aircraft that flew at the NACA High-Speed Flight Research Station, Edwards, California. The bullet-shaped X-1 aircraft were built by Bell Aircraft Corporation, Buffalo, N.Y. for the U.S. Army Air Forces (after 1947, U.S. Air Force) and the National Advisory Committee for Aeronautics (NACA). The X-1 Program was originally designated the XS-1 for eXperimental Sonic. The X-1's mission was to investigate the transonic speed range (speeds from just below to just above the speed of sound) and, if possible, to break the 'sound barrier.' Three different X-1s were built and designated: X-1-1, X-1-2 (later modified to become the X-1E), and X-1-3. The basic X-1 aircraft were flown by a large number of different pilots from 1946 to 1951. The X-1 Program not only proved that humans could go beyond the speed of sound, it reinforced the understanding that technological barriers could be overcome. The X-1s pioneered many structural and aerodynamic advances including extremely thin, yet extremely strong wing sections; supersonic fuselage configurations; control system requirements; powerplant

  3. HMGB1 loves company.

    PubMed

    Bianchi, Marco E

    2009-09-01

    HMGB1, outside of a cell, is a trigger of inflammation and a stimulus for tissue reconstruction; the balance may depend on the complexes it forms with other molecules. HMGB1 is the prime example of a danger signal that originates from the damaged self rather than from invading pathogens. HMGB1 is released by cells that die traumatically and is secreted by cells destined to die and by activated cells of the innate immunity system. As a danger signal, HMGB1 is expected to trigger inflammation, but recent reports indicate that pure recombinant HMGB1 has no proinflammatory activity and only acts as a chemoattractant and a mitogen. However, HMGB1 forms highly inflammatory complexes with ssDNA, LPS, IL-1beta, and nucleosomes, which interact with TLR9, TLR4, IL-1R, and TLR2 receptors, respectively. Thus, HMGB1 has dual activities, solo or in company; I speculate that this may serve our body's necessity to sacrifice or reconstruct tissues as required by the presence or absence of pathogens.

  4. Identification of Dehalobacter reductive dehalogenases that catalyse dechlorination of chloroform, 1,1,1-trichloroethane and 1,1-dichloroethane

    PubMed Central

    Tang, Shuiquan; Edwards, Elizabeth A.

    2013-01-01

    Two novel reductive dehalogenases (RDases) that are highly similar to each other but catalyse distinct dechlorination reactions were identified from Dehalobacter-containing mixed cultures. These two RDases were partially purified from crude protein extracts of anaerobic dechlorinating enrichment cultures using blue native polyacrylamide gel electrophoresis. Gel slices were assayed for dechlorinating activity, and associated proteins were identified using liquid chromatography tandem mass spectrometry with the metagenome of the parent culture as the reference database. The two RDases identified, annotated as CfrA and DcrA, share an amino acid identity of 95.2 per cent, but use different substrates: CfrA dechlorinates chloroform (CF) and 1,1,1-trichloroethane (1,1,1-TCA), but not 1,1-dichloroethane; DcrA dechlorinates 1,1-dichloroethane, but not CF or 1,1,1-TCA. These two novel RDases share no more than 40 per cent amino acid identity to any other known or putative RDases, but both have a twin-arginine motif and two iron–sulfur binding motifs conserved in most RDases. Peptides specific to two putative membrane anchor proteins, annotated as CfrB and DcrB, were also detected in gel slices. PMID:23479748

  5. The RAP1GA1 locus for human Rap1-GTPase activating protein 1 maps to chromosome 1p36.1-->p35.

    PubMed

    Weiss, J; Rubinfeld, B; Polakis, P G; McCormick, F; Cavenee, W K; Arden, K C

    1994-01-01

    Using a panel of somatic cell hybrids we have mapped the locus for Rap1-GTPase activating protein 1 (RAP1GA1) to human chromosome 1. Fluorescence in situ hybridization experiments independently confirmed the chromosomal localization and refined it to 1p36.1-->p35.

  6. Low Luminosity States of the Black Hole Candidate GX 339-4. 1; ASCA and Simultaneous Radio/RXTE Observations

    NASA Technical Reports Server (NTRS)

    Wilms, Joern; Nowak, Michael A.; Dove, James B.; Fender, Robert P.; DiMatteo, Tiziana

    1998-01-01

    We discuss a series of observations of the black hole candidate GX 339-4 in low luminosity, spectrally hard states. We present spectral analysis of three separate archival Advanced Satellite for Cosmology and Astrophysics (ASCA) data sets and eight separate Rossi X-ray Timing Explorer (RXTE) data sets. Three of the RXTE observations were strictly simultaneous with 843 Mega Hertz and 8.3-9.1 Giga Hertz radio observations. All of these observations have (3-9 keV) flux approximately less than 10(exp-9) ergs s(exp-1) CM(exp -2). The ASCA data show evidence for an approximately 6.4 keV Fe line with equivalent width approximately 40 eV, as well as evidence for a soft excess that is well-modeled by a power law plus a multicolor blackbody spectrum with peak temperature approximately equals 150-200 eV. The RXTE data sets also show evidence of an Fe line with equivalent widths approximately equal to 20-1OO eV. Reflection models show a hardening of the RXTE spectra with decreasing X-ray flux; however, these models do not exhibit evidence of a correlation between the photon index of the incident power law flux and the solid angle subtended by the reflector. 'Sphere+disk' Comptonization models and Advection Dominated Accretion Flow (ADAF) models also provide reasonable descriptions of the RXTE data. The former models yield coronal temperatures in the range 20-50 keV and optical depths of r approximately equal to 3. The model fits to the X-ray data, however, do not simultaneously explain the observed radio properties. The most likely source of the radio flux is synchrotron emission from an extended outflow of extent greater than O(10 (exp7) GM/c2).

  7. Arginase-1 deficiency.

    PubMed

    Sin, Yuan Yan; Baron, Garrett; Schulze, Andreas; Funk, Colin D

    2015-12-01

    Arginase-1 (ARG1) deficiency is a rare autosomal recessive disorder that affects the liver-based urea cycle, leading to impaired ureagenesis. This genetic disorder is caused by 40+ mutations found fairly uniformly spread throughout the ARG1 gene, resulting in partial or complete loss of enzyme function, which catalyzes the hydrolysis of arginine to ornithine and urea. ARG1-deficient patients exhibit hyperargininemia with spastic paraparesis, progressive neurological and intellectual impairment, persistent growth retardation, and infrequent episodes of hyperammonemia, a clinical pattern that differs strikingly from other urea cycle disorders. This review briefly highlights the current understanding of the etiology and pathophysiology of ARG1 deficiency derived from clinical case reports and therapeutic strategies stretching over several decades and reports on several exciting new developments regarding the pathophysiology of the disorder using ARG1 global and inducible knockout mouse models. Gene transfer studies in these mice are revealing potential therapeutic options that can be exploited in the future. However, caution is advised in extrapolating results since the lethal disease phenotype in mice is much more severe than in humans indicating that the mouse models may not precisely recapitulate human disease etiology. Finally, some of the functions and implications of ARG1 in non-urea cycle activities are considered. Lingering questions and future areas to be addressed relating to the clinical manifestations of ARG1 deficiency in liver and brain are also presented. Hopefully, this review will spark invigorated research efforts that lead to treatments with better clinical outcomes. PMID:26467175

  8. 1,4-Dioxane

    Integrated Risk Information System (IRIS)

    1,4 - Dioxane ; CASRN 123 - 91 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic Eff

  9. 1,2-Dichlorobenzene

    Integrated Risk Information System (IRIS)

    1,2 - Dichlorobenzene ; CASRN 95 - 50 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge

  10. 1,3-Dichlorobenzene

    Integrated Risk Information System (IRIS)

    1,3 - Dichlorobenzene ; CASRN 541 - 73 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinog

  11. Diabetes Type 1

    MedlinePlus

    Diabetes means your blood glucose, or blood sugar, levels are too high. With type 1 diabetes, your pancreas does not make insulin. Insulin is ... kidneys, nerves, and gums and teeth. Type 1 diabetes happens most often in children and young adults ...

  12. MAP3K1

    PubMed Central

    Pham, Trang T.; Angus, Steven P.

    2013-01-01

    MAP3K1 is a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family of serine/threonine kinases. MAP3K1 regulates JNK activation and is unique among human kinases in that it also encodes an E3 ligase domain that ubiquitylates c-Jun and ERK1/2. Full length MAP3K1 regulates cell migration and contributes to pro-survival signaling while its caspase 3-mediated cleavage generates a C-terminal kinase domain that promotes apoptosis. The critical function of MAP3K1 in cell fate decisions suggests that it may be a target for deregulation in cancer. Recent large-scale genomic studies have revealed that MAP3K1 copy number loss and somatic missense or nonsense mutations are observed in a significant number of different cancers, being most prominent in luminal breast cancer. The alteration of MAP3K1 in diverse cancer types demonstrates the importance of defining phenotypes for possible therapeutic targeting of tumor cell vulnerabilities created when MAP3K1 function is lost or gained. PMID:24386504

  13. A1C

    MedlinePlus

    A1C is a blood test for type 2 diabetes and prediabetes. It measures your average blood glucose, or blood sugar, level over the past 3 ... A1C alone or in combination with other diabetes tests to make a diagnosis. They also use the ...

  14. MR1 discovery.

    PubMed

    Hashimoto, Keiichiro

    2016-08-01

    The moment of MR1 discovery is described. The MR1 gene is the first and the last reported human MHC-related gene intentionally isolated from the human genome composed of three billion base pairs. Evolutionary considerations formed the basis of its isolation. Some details surrounding the moment and some retrospective descriptions with various kinds of encounters are also included.

  15. 40 CFR 721.10435 - Phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)-.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Phenol, 2-(1-methyl-1-phenylethyl)-4... Significant New Uses for Specific Chemical Substances § 721.10435 Phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3... chemical substance identified as phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)- (PMN...

  16. 40 CFR 721.10435 - Phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)-.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Phenol, 2-(1-methyl-1-phenylethyl)-4... Significant New Uses for Specific Chemical Substances § 721.10435 Phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3... chemical substance identified as phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)- (PMN...

  17. 26 CFR 1.704-1 - Partner's distributive share.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... §§ 1.704-1T(b)(1)(ii)(b)(1) and 1.704-1T(b)(4)(xi) as in effect prior to October 19, 2006 (see 26 CFR..., see §§ 1.704-1T(b)(1)(ii)(b)(1) and 1.704-1T(b)(4)(xi) as in effect prior to October 19, 2006 (26...

  18. 26 CFR 1.704-1 - Partner's distributive share.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... §§ 1.704-1T(b)(1)(ii)(b)(1) and 1.704-1T(b)(4)(xi) as in effect prior to October 19, 2006 (see 26 CFR..., see §§ 1.704-1T(b)(1)(ii)(b)(1) and 1.704-1T(b)(4)(xi) as in effect prior to October 19, 2006 (26...

  19. Adsorption of dichlorodifluoromethane, chlorodifluoromethane, chloropentafluoroethane, 1,1-difluoroethane, and 1,1,1,2-tetrafluoroethane on silica gel

    SciTech Connect

    Frere, M.; Berlier, K.; Bougard, J.; Jadot, R. . Service de Thermodynamique)

    1994-10-01

    The CFC's (chlorofluorocarbons) are used as working refrigerants fluids. The most commonly used are R12, R22, and R502 (48.8% R22 and 51.2% R115). Recent concerns of the effects of CFC's on the ozone layer require the development of efficient recovery methods. One technique is to adsorb the fluids onto a porous medium such as silica gel. Thermodynamic data on the adsorption of dichlorodifluoromethane (R12), chlorodifluoromethane (R22), chloropentafluoroethane (R115), 1,1-difluoroethane (R152a), and 1,1,1,2-tetrafluoroethane (R134a) on silica gel are required for the design of recovery units. The results are presented here.

  20. 26 CFR 1.6109-1 - Identifying numbers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., see 26 CFR § 1.6109-1 (revised as of April 1, 1973). ... 26 Internal Revenue 13 2011-04-01 2011-04-01 false Identifying numbers. 1.6109-1 Section 1.6109-1...) INCOME TAXES (CONTINUED) Miscellaneous Provisions § 1.6109-1 Identifying numbers. (a) Information to...

  1. 26 CFR 1.6109-1 - Identifying numbers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., see 26 CFR § 1.6109-1 (revised as of April 1, 1973). ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Identifying numbers. 1.6109-1 Section 1.6109-1...) INCOME TAXES Miscellaneous Provisions § 1.6109-1 Identifying numbers. (a) Information to be...

  2. Spacelab Life Sciences-1

    NASA Technical Reports Server (NTRS)

    Dalton, Bonnie P.; Jahns, Gary; Meylor, John; Hawes, Nikki; Fast, Tom N.; Zarow, Greg

    1995-01-01

    This report provides an historical overview of the Spacelab Life Sciences-1 (SLS-1) mission along with the resultant biomaintenance data and investigators' findings. Only the nonhuman elements, developed by Ames Research Center (ARC) researchers, are addressed herein. The STS-40 flight of SLS-1, in June 1991, was the first spacelab flown after 'return to orbit', it was also the first spacelab mission specifically designated as a Life Sciences Spacelab. The experiments performed provided baseline data for both hardware and rodents used in succeeding missions.

  3. 1-Benzyl-4-(naphthalen-1-yl)-1H-1,2,3-triazole

    PubMed Central

    Sarmiento-Sánchez, Juan I.; Aguirre, Gerardo; Rivero, Ignacio A.

    2011-01-01

    In the title compound, C19H15N3, the benzyl group is almost perpendicular to the triazole ring [dihedral angle = 80.64 (8)°], while the napthyl group makes an angle of 30.27 (12)° with the plane of the triazole ring. This conformation is different from the 1-benzyl-4-phenyl-1H-1,2,3-triazole analogue, which has the benzyl ring system at an angle of 87.94° and the phenyl group at an angle of 3.35° to the plane of the triazole ring. PMID:21837221

  4. The dehydrogenation of CH4 on Rh(1 1 1), Rh(1 1 0) and Rh(1 0 0) surfaces: A density functional theory study

    NASA Astrophysics Data System (ADS)

    Wang, Baojun; Song, Luzhi; Zhang, Riguang

    2012-02-01

    CH4 dehydrogenation on Rh(1 1 1), Rh(1 1 0) and Rh(1 0 0) surfaces has been investigated by using density functional theory (DFT) slab calculations. On the basis of energy analysis, the preferred adsorption sites of CHx (x = 0-4) and H species on Rh(1 1 1), Rh(1 1 0) and Rh(1 0 0) surfaces are located, respectively. Then, the stable co-adsorption configurations of CHx (x = 0-3) and H are obtained. Further, the kinetic results of CH4 dehydrogenation show that on Rh(1 1 1) and Rh(1 0 0) surfaces, CH is the most abundant species for CH4 dissociation; on Rh(1 1 0) surface, CH2 is the most abundant species, our results suggest that Rh catalyst can resist the carbon deposition in the CH4 dehydrogenation. Finally, results of thermodynamic and kinetic show that CH4 dehydrogenation on Rh(1 0 0) surface is the most preferable reaction pathway in comparison with that on Rh(1 1 1) and Rh(1 1 0) surfaces.

  5. Thiomethylstilbenes as inhibitors of CYP1A1, CYP1A2 and CYP1B1 activities.

    PubMed

    Mikstacka, Renata; Baer-Dubowska, Wanda; Wieczorek, Marcin; Sobiak, Stanislaw

    2008-06-01

    Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural stilbene derivative occurring in grapes, peanuts and red wine. Its chemopreventive action has been established in studies on animal models. Recently, numerous classes of compounds with stilbene backbone have been investigated for their biological activity concerning cancer prevention; e. g. resveratrol methyl ethers appeared to be specific and potent inhibitors of cytochromes P450 (CYP) family 1 involved in the activation of procarcinogens. Since the replacement of the 4'-hydroxyl with a thiomethyl group is supposed to reduce toxicity of stilbene derivatives, the purpose of this study was the synthesis and evaluation of a series of 4-thiomethyl-trans-stilbene derivatives differing in a number and position of additional methoxy groups. Their inhibitory potency toward human recombinant CYPs: CYP1A1, CYP1A2 and CYP1B1 have been studied and compared with the effect of resveratrol and its analogues. Among compounds tested, 2-methoxy-4'-thiomethyl-trans-stilbene and 3-methoxy-4'-thiomethyl-trans-stilbene demonstrated the most potent and selective inhibitory effect on CYP1A1 and CYP1B1 activities. The results of our study indicate that modification of stilbene derivatives with thiomethyl group may influence the selectivity and inhibitory potency of these compounds toward P450 isozymes. Thus, it should be considered in developing new chemopreventive agents based on their mechanism of action.

  6. DAX-1 (NR0B1) and steroidogenic factor-1 (SF-1, NR5A1) in human disease.

    PubMed

    Suntharalingham, Jenifer P; Buonocore, Federica; Duncan, Andrew J; Achermann, John C

    2015-08-01

    DAX-1 (NR0B1) and SF-1 (NR5A1) are two nuclear receptor transcription factors that play a key role in human adrenal and reproductive development. Loss of DAX-1 function is classically associated with X-linked adrenal hypoplasia congenita. This condition typically affects boys and presents as primary adrenal insufficiency in early infancy or childhood, hypogonadotropic hypogonadism at puberty and impaired spermatogenesis. Late onset forms of this condition and variant phenotypes are increasingly recognized. In contrast, disruption of SF-1 only rarely causes adrenal insufficiency, usually in combination with testicular dysgenesis. Variants in SF-1/NR5A1 more commonly cause a spectrum of reproductive phenotypes ranging from 46,XY DSD (partial testicular dysgenesis or reduced androgen production) and hypospadias to male factor infertility or primary ovarian insufficiency. Making a specific diagnosis of DAX-1 or SF-1 associated conditions is important for long-term monitoring of endocrine and reproductive function, appropriate genetic counselling for family members, and for providing appropriate informed support for young people. PMID:26303087

  7. Liquid-liquid equilibria for hydrogen fluoride + 1,1-dichloro-1-fluoroethane + 1-chloro-1,1-difluoroethane at {minus}20 and 20 C

    SciTech Connect

    Kang, Y.W.; Lee, Y.Y.

    1995-03-01

    1,1-Dichloro-1-fluoroethane is presently under consideration as a replacement for trichlorofluoromethane, which is widely used as a foam blowing agent. 1-Chloro-1,1-difluoroethane is the major raw material for the production of poly(vinylidene fluoride). These two materials are normally manufactured by the fluorination of 1,1,1-trichloroethane or vinylidene chloride with hydrogen fluoride. A phase separator is normally used to retrieve hydrogen fluoride from the product stream. To design the phase separator, liquid-liquid equilibrium data are required. Liquid-liquid equilibria for the ternary system (hydrogen fluoride + 1,1-dichloro-1-fluoroethane + 1-chloro-1,1-difluoroethane) have been measured at {minus}20 and 20 C. The results are correlated with the NRTL model, and the relevant parameters are presented.

  8. 40 CFR 721.10373 - 1H-Imidazole, 1-(1-methylethyl)-.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false 1H-Imidazole, 1-(1-methylethyl)-. 721... Substances § 721.10373 1H-Imidazole, 1-(1-methylethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as 1H-imidazole, 1-(1-methylethyl)- (PMN...

  9. 40 CFR 721.10373 - 1H-Imidazole, 1-(1-methylethyl)-.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false 1H-Imidazole, 1-(1-methylethyl)-. 721... Substances § 721.10373 1H-Imidazole, 1-(1-methylethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as 1H-imidazole, 1-(1-methylethyl)- (PMN...

  10. 40 CFR 721.10373 - 1H-Imidazole, 1-(1-methylethyl)-.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false 1H-Imidazole, 1-(1-methylethyl)-. 721... Substances § 721.10373 1H-Imidazole, 1-(1-methylethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as 1H-imidazole, 1-(1-methylethyl)- (PMN...

  11. Substituted 1,1,1-Triaryl-2,2,2-Trifluoroethanes and processes for their synthesis

    NASA Technical Reports Server (NTRS)

    Alston, William B. (Inventor); Gratz, Roy F. (Inventor)

    1988-01-01

    Synthetic procedures are described for tetraalkyls, tetraacids and dianhydrides substituted 1,1,1-triaryl-2,2,2-trifluoroethanes which comprises: (1) 1,1-bis(dialkylaryl)-1 aryl-2,2,2-trifluoroethane; (2) 1,1-bis(dicarboxyaryl)-1 aryl-2,2,2-trifluoroethane; or (3) cyclic dianhydride or diamine of 1,1-bis(dialkylaryl)-1 aryl-2,2,2,-trifluoroethanes.

  12. PBT-1 Prana Biotechnology.

    PubMed

    Huckle, Richard

    2005-01-01

    PBT-1 (clioquinol), is undergoing phase II clinical trials by Prana Biotechnology Ltd for the potential treatment of Alzheimer's disease. By October 2004, the company had planned phase III trials for the first half of 2005. PMID:15675609

  13. IML-1 Logo

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The primary payload for Space Shuttle Mission STS-42, launched January 22, 1992, was the International Microgravity Laboratory-1 (IML-1), a pressurized manned Spacelab module. The goal of IML-1 was to explore in depth the complex effects of weightlessness of living organisms and materials processing. Around-the-clock research was performed on the human nervous system's adaptation to low gravity and effects of microgravity on other life forms such as shrimp eggs, lentil seedlings, fruit fly eggs, and bacteria. Materials processing experiments were also conducted, including crystal growth from a variety of substances such as enzymes, mercury iodide and a virus. More than 200 scientists from 16 countries participated in the investigations. This is the logo or emblem that was designed to represent the IML-1 payload.

  14. Vitamin B1

    MedlinePlus

    ... Flash 6 » Sound: No High score: Yes Credits » Chicken Farm Game - Why do we need vitamin B1? - ... save lives. You have one minute to feed chickens suffering from beriberi with the correct food to ...

  15. A1C Test

    MedlinePlus

    ... to minimize the complications caused by chronically elevated glucose levels, such as progressive damage to body organs like the kidneys, eyes, cardiovascular system, and nerves. The A1c test result ...

  16. Type 1 diabetes

    MedlinePlus

    ... your diabetes. But, you are the most important person in managing your diabetes. You should know the basic steps ... to your doctor before starting any exercise program. People with type 1 ... MANAGING YOUR BLOOD SUGAR Checking your blood sugar level ...

  17. Interferon Alfacon-1 Injection

    MedlinePlus

    ... ordered interferon alfacon-1 to help treat your hepatitis C infection. The drug will be injected under your ... a synthetic interferon that helps to prevent the hepatitis C virus from growing inside your body. This medication ...

  18. Type 1 diabetes

    PubMed Central

    Atkinson, Mark A; Eisenbarth, George S; Michels, Aaron W

    2015-01-01

    Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes has grown substantially, particularly with regard to disease prediction and heterogeneity, pancreatic pathology, and epidemiology. Technological improvements in insulin pumps and continuous glucose monitors help patients with type 1 diabetes manage the challenge of lifelong insulin administration. Agents that show promise for averting debilitating disease-associated complications have also been identified. However, despite broad organisational, intellectual, and fiscal investments, no means for preventing or curing type 1 diabetes exists, and, globally, the quality of diabetes management remains uneven. This Seminar discusses current progress in epidemiology, pathology, diagnosis, and treatment of type 1 diabetes, and prospects for an improved future for individuals with this disease. PMID:23890997

  19. Chapter 1: Introduction

    SciTech Connect

    None, None

    2009-01-18

    This report describes analysis undertaken by EERE to better understand the extent to which the technologies and market improvements funded by its fiscal year (FY) 2006 Budget Request1 will make energy more affordable, cleaner, and more reliable.

  20. X1 Exoskeleton

    NASA Video Gallery

    NASA's Ironman-Like Exoskeleton Could Give Astronauts, Paraplegics Improved Mobility and Strength. While NASA's X1 robotic exoskeleton can't do what you see in the movies, the latest robotic, space...

  1. Child with NF1

    MedlinePlus

    ... disorder. Such discoveries have already resulted in new methods of diagnosis. The likelihood of finding effective treatments for NF1, in the years ahead, is promising. Scientists are actively researching the disorder at centers throughout ...

  2. Probability 1/e

    ERIC Educational Resources Information Center

    Koo, Reginald; Jones, Martin L.

    2011-01-01

    Quite a number of interesting problems in probability feature an event with probability equal to 1/e. This article discusses three such problems and attempts to explain why this probability occurs with such frequency.

  3. CSF-1 signal transduction.

    PubMed

    Hamilton, J A

    1997-08-01

    Colony-stimulating factor-1 (CSF-1) or macrophage-CSF (M-CSF) is a growth factor involved in the proliferation, differentiation, and activation of cells of the monocyte/macrophage lineage. Its receptor is the homodimeric, tyrosine kinase product of the c-fms proto-oncogene, which contains a so-called kinase insert domain. This review focuses mainly on recent studies of signal transduction events that are initiated on interaction of CSF-1 and its receptor. A summary is given of the tyrosine autophosphorylation sites on c-Fms identified to date, including their interaction with various substrates and their possible significance for signal transduction and cellular function. In addition, the signal transduction pathways that have been identified to lie downstream of activated c-Fms are reviewed. Although it is apparent that there have been many recent significant developments in our understanding of CSF-1 signaling, a number of examples are mentioned of significant discrepancies in the literature, some possible reasons for which can sometimes be offered. It is also apparent that any particular biochemical response or signal transduction pathway, even though widespread in other ligand receptor/cellular systems, including those with similar receptor structures to c-Fms, may not be relevant to CSF-1 signaling. The relevance of any potentially important molecular signaling pathway activated by CSF-1 in cells in vitro will ultimately have to be related to the functions of monocytes/macrophages in vivo.

  4. Polymorphisms of UGT1A1*6, UGT1A1*27 & UGT1A1*28 in three major ethnic groups from Malaysia

    PubMed Central

    Teh, L. K.; Hashim, H.; Zakaria, Z. A.; Salleh, M. Z.

    2012-01-01

    Background & objectives: Genetic polymorphisms of uridine diphosphate glucuronyltransferase 1A1 (UGT1A1) have been associated with a wide variation of responses among patients prescribed with irinotecan. Lack of this enzyme is known to be associated with a high incidence of severe toxicity. The objective of this study was to investigate the prevalence of three different variants of UGT1A1 (UGT1A1*6, UGT1A1*27 and UGT1A1*28), which are associated with reduced enzyme activity and increased irinotecan toxicity, in the three main ethnic groups in Malaysia (Malays, Chinese and Indians). Methods: A total of 306 healthy unrelated volunteers were screened for UGT1A1*28, UGT1A1*6 and UGT1A1*27. Blood samples (5 ml) were obtained from each subject and DNA was extracted. PCR based methods were designed and validated for detection of UGT1A1*6, UGT1A1*27 and UGT1A1*28. Direct DNA sequencing was performed to validate the results of randomly selected samples. Results: Malays and Indian have two-fold higher frequency of homozygous of UGT1A1*28 (7TA/7TA) which was 8 and 8.8 per cent, respectively compared to the Chinese (4.9%). However, the distribution of UGT1A1*6 and UGT1A1*27 showed no significant differences among them. UGT1A1*27 which has not been detected in Caucasian and African American population, was found in the Malaysian Malays (3.33%) and Malaysian Chinese (2.0%). Interpretation & conclusions: There was interethnic variability in the frequency of UGT1A1*28 in the Malaysian population. Our results suggest that genotyping of UGT1A1*6, UGT1A1*28 and UGT1A1*27 need to be performed before patients are prescribed with irinotecan due to their high prevalence of allelic variant which could lead to adverse drug reaction. PMID:22960892

  5. Thermal chemistry of 2-halo-1-propanols on Ni(1 1 1) and Cu(1 1 1) surfaces: A UBI-QEP energetic modeling

    NASA Astrophysics Data System (ADS)

    Mirzanejad, Amir

    2015-12-01

    The effect of β-halogen substitutions on the thermal chemistry of 1-propanol over Ni(1 1 1) and Cu(1 1 1) single-crystal surfaces was investigated using the method of unity bond index-quadratic exponential potential (UBI-QEP). This method was employed to investigate the energetics of the catalytic conversion routes of the ad-molecule mainly at the zero-coverage limit by calculating activation barriers and enthalpy changes for surface reactions. The alcohol molecule can be oxidized partially and totally over the Ni surface, however, the molecule is rather inactive on Cu. The β-halogen substitution makes extensive conversion of the alcohol possible on the Cu surface and changes conversion pathways on the Ni surface. It was found that halogen substitution as well as hydrogen bonding can affect the reactivity and conversion routes of the molecules on Ni and Cu surfaces. On account of energetic criteria, the predicted routes for decompositions and the TPD patterns for the surface species are in accord with the available experimental observations.

  6. 26 CFR 1.952-1 - Subpart F income defined.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 957(b). (b) Exclusion of U.S. income—(1) Taxable years beginning before January 1, 1967. For rules applicable to taxable years beginning before January 1, 1967, see 26 CFR 1.952-1(b)(1) (Revisedof April 1... of an inclusion under section 951(a)(1)(A) from each separate category as defined in §...

  7. 26 CFR 1.50-1 - Restoration of credit.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Restoration of credit. 1.50-1 Section 1.50-1... Computing Credit for Investment in Certain Depreciable Property § 1.50-1 Restoration of credit. (a) In general. Section 49(a) (relating to termination of credit) does not apply to property— (1)...

  8. 26 CFR 1.1377-1 - Pro rata share.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Pro rata share. 1.1377-1 Section 1.1377-1...) INCOME TAXES Small Business Corporations and Their Shareholders § 1.1377-1 Pro rata share. (a) Computation of pro rata shares—(1) In general. For purposes of subchapter S of chapter 1 of the...

  9. 26 CFR 1.666(a)-1 - Amount allocated.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Amount allocated. 1.666(a)-1 Section 1.666(a)-1... Beginning Before January 1, 1969 § 1.666(a)-1 Amount allocated. (a)(1) If a trust other than a foreign trust... had the following amounts of undistributed net income: Year Undistributed net income—portion of...

  10. 26 CFR 1.815-1 - Taxable years affected.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Taxable years affected. 1.815-1 Section 1.815-1...) INCOME TAXES (CONTINUED) Distributions to Shareholders § 1.815-1 Taxable years affected. Sections 1.815-2 through 1.815-6, except as otherwise provided therein, are applicable only to taxable years...

  11. 26 CFR 1.812-1 - Taxable years affected.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Taxable years affected. 1.812-1 Section 1.812-1...) INCOME TAXES Gain and Loss from Operations § 1.812-1 Taxable years affected. Sections 1.812-2 through 1.812-8, except as otherwise provided therein, are applicable only to taxable years beginning...

  12. 26 CFR 1.809-1 - Taxable years affected.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Taxable years affected. 1.809-1 Section 1.809-1...) INCOME TAXES Gain and Loss from Operations § 1.809-1 Taxable years affected. Sections 1.809 through 1.809-8, except as otherwise provided therein, are applicable only to taxable years beginning...

  13. 26 CFR 1.818-1 - Taxable years affected.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Taxable years affected. 1.818-1 Section 1.818-1...) INCOME TAXES (CONTINUED) Miscellaneous Provisions § 1.818-1 Taxable years affected. Sections 1.818-2 through 1.818-8, except as otherwise provided therein, are applicable only to taxable years...

  14. 26 CFR 1.817-1 - Taxable years affected.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Taxable years affected. 1.817-1 Section 1.817-1...) INCOME TAXES (CONTINUED) Miscellaneous Provisions § 1.817-1 Taxable years affected. Except as otherwise provided therein, §§ 1.817-2 through 1.817-4 are applicable only to taxable years beginning after...

  15. 26 CFR 1.817-1 - Taxable years affected.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Taxable years affected. 1.817-1 Section 1.817-1...) INCOME TAXES Miscellaneous Provisions § 1.817-1 Taxable years affected. Except as otherwise provided therein, §§ 1.817-2 through 1.817-4 are applicable only to taxable years beginning after December 31,...

  16. 26 CFR 1.809-1 - Taxable years affected.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Taxable years affected. 1.809-1 Section 1.809-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.809-1 Taxable years affected. Sections 1.809 through 1.809-8, except as otherwise provided therein, are applicable only to taxable years...

  17. 26 CFR 1.810-1 - Taxable years affected.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Taxable years affected. 1.810-1 Section 1.810-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.810-1 Taxable years affected. Sections 1.810-2 through 1.810-4 are applicable only to taxable years beginning after December 31, 1957, and all...

  18. 26 CFR 1.815-1 - Taxable years affected.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Taxable years affected. 1.815-1 Section 1.815-1...) INCOME TAXES (CONTINUED) Distributions to Shareholders § 1.815-1 Taxable years affected. Sections 1.815-2 through 1.815-6, except as otherwise provided therein, are applicable only to taxable years...

  19. 26 CFR 1.810-1 - Taxable years affected.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Taxable years affected. 1.810-1 Section 1.810-1...) INCOME TAXES Gain and Loss from Operations § 1.810-1 Taxable years affected. Sections 1.810-2 through 1.810-4 are applicable only to taxable years beginning after December 31, 1957, and all references...

  20. 26 CFR 1.817-1 - Taxable years affected.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Taxable years affected. 1.817-1 Section 1.817-1...) INCOME TAXES (CONTINUED) Miscellaneous Provisions § 1.817-1 Taxable years affected. Except as otherwise provided therein, §§ 1.817-2 through 1.817-4 are applicable only to taxable years beginning after...

  1. 26 CFR 1.818-1 - Taxable years affected.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Taxable years affected. 1.818-1 Section 1.818-1...) INCOME TAXES (CONTINUED) Miscellaneous Provisions § 1.818-1 Taxable years affected. Sections 1.818-2 through 1.818-8, except as otherwise provided therein, are applicable only to taxable years...

  2. 26 CFR 1.812-1 - Taxable years affected.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Taxable years affected. 1.812-1 Section 1.812-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.812-1 Taxable years affected. Sections 1.812-2 through 1.812-8, except as otherwise provided therein, are applicable only to taxable years...

  3. 26 CFR 1.815-1 - Taxable years affected.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Taxable years affected. 1.815-1 Section 1.815-1...) INCOME TAXES (CONTINUED) Distributions to Shareholders § 1.815-1 Taxable years affected. Sections 1.815-2 through 1.815-6, except as otherwise provided therein, are applicable only to taxable years...

  4. 26 CFR 1.812-1 - Taxable years affected.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Taxable years affected. 1.812-1 Section 1.812-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.812-1 Taxable years affected. Sections 1.812-2 through 1.812-8, except as otherwise provided therein, are applicable only to taxable years...

  5. 26 CFR 1.810-1 - Taxable years affected.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Taxable years affected. 1.810-1 Section 1.810-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.810-1 Taxable years affected. Sections 1.810-2 through 1.810-4 are applicable only to taxable years beginning after December 31, 1957, and all...

  6. 26 CFR 1.812-1 - Taxable years affected.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Taxable years affected. 1.812-1 Section 1.812-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.812-1 Taxable years affected. Sections 1.812-2 through 1.812-8, except as otherwise provided therein, are applicable only to taxable years...

  7. 26 CFR 1.809-1 - Taxable years affected.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Taxable years affected. 1.809-1 Section 1.809-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.809-1 Taxable years affected. Sections 1.809 through 1.809-8, except as otherwise provided therein, are applicable only to taxable years...

  8. 26 CFR 1.817-1 - Taxable years affected.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Taxable years affected. 1.817-1 Section 1.817-1...) INCOME TAXES (CONTINUED) Miscellaneous Provisions § 1.817-1 Taxable years affected. Except as otherwise provided therein, §§ 1.817-2 through 1.817-4 are applicable only to taxable years beginning after...

  9. 26 CFR 1.810-1 - Taxable years affected.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Taxable years affected. 1.810-1 Section 1.810-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.810-1 Taxable years affected. Sections 1.810-2 through 1.810-4 are applicable only to taxable years beginning after December 31, 1957, and all...

  10. 26 CFR 1.818-1 - Taxable years affected.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Taxable years affected. 1.818-1 Section 1.818-1...) INCOME TAXES (CONTINUED) Miscellaneous Provisions § 1.818-1 Taxable years affected. Sections 1.818-2 through 1.818-8, except as otherwise provided therein, are applicable only to taxable years...

  11. 26 CFR 1.809-1 - Taxable years affected.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Taxable years affected. 1.809-1 Section 1.809-1...) INCOME TAXES (CONTINUED) Gain and Loss from Operations § 1.809-1 Taxable years affected. Sections 1.809 through 1.809-8, except as otherwise provided therein, are applicable only to taxable years...

  12. 26 CFR 1.280B-1 - Demolition of structures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., the term structure means a building, as defined in § 1.48-1(e)(1), including the structural components... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Demolition of structures. 1.280B-1 Section 1... (CONTINUED) INCOME TAXES (CONTINUED) Items Not Deductible § 1.280B-1 Demolition of structures. (a) In...

  13. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or former section 44C provides a residential energy credit against the tax imposed by chapter 1 of the...

  14. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 1 2013-04-01 2013-04-01 false Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or former section 44C provides a residential energy credit against the tax imposed by chapter 1 of the...

  15. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or former section 44C provides a residential energy credit against the tax imposed by chapter 1 of the...

  16. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or former section 44C provides a residential energy credit against the tax imposed by chapter 1 of the...

  17. 26 CFR 1.23-1 - Residential energy credit.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 1 2012-04-01 2012-04-01 false Residential energy credit. 1.23-1 Section 1.23-1... Rates During A Taxable Year § 1.23-1 Residential energy credit. (a) General rule. Section 23 or former section 44C provides a residential energy credit against the tax imposed by chapter 1 of the...

  18. 7 CFR 1.1 - Purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Purpose and scope. 1.1 Section 1.1 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.1 Purpose and scope... process. This subpart also serves as the implementing regulations (referred to in § 1.3,...

  19. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  20. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  1. 7 CFR 1.1 - Purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false Purpose and scope. 1.1 Section 1.1 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.1 Purpose and scope... process. This subpart also serves as the implementing regulations (referred to in § 1.3,...

  2. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  3. 7 CFR 1.1 - Purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false Purpose and scope. 1.1 Section 1.1 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.1 Purpose and scope... process. This subpart also serves as the implementing regulations (referred to in § 1.3,...

  4. 26 CFR 1.62-1 - Adjusted gross income.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 CFR part 1 (§§ 1.61 to 1.169) revised April 1, 1992). (d)-(h) (i) Effective date. Paragraph (c) of... 26 Internal Revenue 2 2013-04-01 2013-04-01 false Adjusted gross income. 1.62-1 Section 1.62-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX...

  5. 26 CFR 1.62-1 - Adjusted gross income.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 CFR part 1 (§§ 1.61 to 1.169) revised April 1, 1992). (d)-(h) (i) Effective date. Paragraph (c) of... 26 Internal Revenue 2 2012-04-01 2012-04-01 false Adjusted gross income. 1.62-1 Section 1.62-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX...

  6. 7 CFR 1.1 - Purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Purpose and scope. 1.1 Section 1.1 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.1 Purpose and scope... process. This subpart also serves as the implementing regulations (referred to in § 1.3,...

  7. 45 CFR 1.1 - Location of HHS regulations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Location of HHS regulations. 1.1 Section 1.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are...

  8. 7 CFR 1.1 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Purpose and scope. 1.1 Section 1.1 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.1 Purpose and scope... process. This subpart also serves as the implementing regulations (referred to in § 1.3,...

  9. 49 CFR 172.522 - EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3... INFORMATION, TRAINING REQUIREMENTS, AND SECURITY PLANS Placarding § 172.522 EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards. (a) Except for size and color, the EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES...

  10. 49 CFR 172.522 - EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3... INFORMATION, TRAINING REQUIREMENTS, AND SECURITY PLANS Placarding § 172.522 EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards. (a) Except for size and color, the EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES...

  11. 49 CFR 172.522 - EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3... INFORMATION, TRAINING REQUIREMENTS, AND SECURITY PLANS Placarding § 172.522 EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards. (a) Except for size and color, the EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES...

  12. 49 CFR 172.522 - EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3... INFORMATION, TRAINING REQUIREMENTS, AND SECURITY PLANS Placarding § 172.522 EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES 1.3 placards. (a) Except for size and color, the EXPLOSIVES 1.1, EXPLOSIVES 1.2 and EXPLOSIVES...

  13. 26 CFR 1.168(i)-1 - General asset accounts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... effect prior to June 17, 2004 (§ 1.168(i)-1(b)(1) as contained in 26 CFR part 1 edition revised as of... February 27, 2004 (§ 1.168(i)-1 as contained in 26 CFR part 1 edition revised as of April 1, 2003). ... 26 Internal Revenue 2 2011-04-01 2011-04-01 false General asset accounts. 1.168(i)-1 Section...

  14. 26 CFR 1.475(g)-1 - Effective dates.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... (ii) A taxpayer may rely on the rules set out in § 1.475(c)-1T(b) (as contained in 26 CFR part 1... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Effective dates. 1.475(g)-1 Section 1.475(g)-1...) INCOME TAXES Inventories § 1.475(g)-1 Effective dates. (a)-(b) (c) Section 1.475(a)-3...

  15. Flap Endonuclease 1

    PubMed Central

    Balakrishnan, Lata; Bambara, Robert A.

    2013-01-01

    First discovered as a structure-specific endonuclease that evolved to cut at the base of single-stranded flaps, flap endonuclease (FEN1) is now recognized as a central component of cellular DNA metabolism. Substrate specificity allows FEN1 to process intermediates of Okazaki fragment maturation, long-patch base excision repair, telomere maintenance, and stalled replication fork rescue. For Okazaki fragments, the RNA primer is displaced into a 5′ flap and then cleaved off. FEN1 binds to the flap base and then threads the 5′ end of the flap through its helical arch and active site to create a configuration for cleavage. The threading requirement prevents this active nuclease from cutting the single-stranded template between Okazaki fragments. FEN1 efficiency and specificity are critical to the maintenance of genome fidelity. Overall, recent advances in our knowledge of FEN1 suggest that it was an ancient protein that has been fine-tuned over eons to coordinate many essential DNA transactions. PMID:23451868

  16. Synthesis, structure and properties of 1,1'-diamino- and1,1'-diazidoferrocene

    SciTech Connect

    Shafir, Alexandr; Power, Maurice P.; Whitener, Glenn D.; Arnold,John

    2000-05-14

    We report an improved synthesis of 1,1'-diaminoferrocene, employing the reduction of 1,1'-diazidoferrocene with H2-Pd/C, along with extensive characterization data for both compounds. Diaminoferrocene under goes a reversible 1e- oxidation in CH3CN at a potential of -602 mVvs Fc0/+, one of the most negative redox potentials for a ferrocene derivative. The chemical reversibility of this process was confirmed by isolation of the stable, 17-electron[Fc(NH2)2]+ cation as PF6-, OTf-, and TCNE-salts. In the solid state, diaminoferrocene exists in two conformations: one with the NH2 groups eclipsed, and the other with the NH2 groups offset by one-fifth turn around the Cp-Fe-Cp axis. Diazidoferrocene, on the other hand, exhibits only the fully eclipsed conformation in the solid state. The Fe-Cp (centroid) vectors in the diazidoferrocene molecules are roughly aligned with the crystallographic-axis, and the molecules form layers perpendicular to this axis. The compound is thermally unstable at elevated temperatures, and rapid heating above its melting point results in explosion.

  17. TRUPACT-1 implementation plan

    SciTech Connect

    Hurley, J.D.; Tappen, J.J. . Joint Integration Office); Christensen, D.S. )

    1985-09-01

    TRUPACT-1, the TRansUranic PACkage Transporter is a packaging designed to transport defense contact handled transuranic (CH-TRU) waste from generating and interim TRU waste storage facilities to the Waste Isolation Pilot Plant (WIPP). Prior to fabrication and procurement of a full fleet, an initial design (TRUPACT-1) will be introduced to the defense TRU waste complex through use in an operational prototype fleet which will consist of Units 1, 2, and 3. In an effort to provide a relatively smooth introduction of the TRUPACT-1, the TRUPACT Technical Team (TTT) has developed the following implementation plan. The plan provides detailed information on user handling opportunities, schedules, equipment, responsibilities, reporting and data collection activities to be performed. The intent of this document is to provide users of the TRUPACT-1 with a guidance document, complete with references, that will allow the smooth introduction of this new transportation system by providing the information necessary for collecting operational, performance and cost data. These data will be used in modeling and full fleet design and procurement activities. In addition, these data will help fine tune procedures in the inspection and maintenance document and the operational document. Additional objectives of this plan are to aid in the establishment of site operational, inspection and maintenance procedures as well as training of site operators and briefing state and local officials.

  18. HERG1 channelopathies

    PubMed Central

    2009-01-01

    Human ether a go-go-related gene type 1 (hERG1) K+ channels conduct the rapid delayed rectifier K+ current and mediate action potential repolarization in the heart. Mutations in KCNH2 (the gene that encodes hERG1) causes LQT2, one of the most common forms of long QT syndrome, a disorder of cardiac repolarization that predisposes affected subjects to ventricular arrhythmia and increases the risk of sudden cardiac death. Hundreds of LQT2-associated mutations have been described, and most cause a loss of function by disrupting subunit folding, assembly, or trafficking of the channel to the cell surface. Loss-of-function mutations in hERG1 channels have also recently been implicated in epilepsy. A single gain-of-function mutation has been described that causes short QT syndrome and cardiac arrhythmia. In addition, up-regulation of hERG1 channel expression has been demonstrated in specific tumors and has been associated with skeletal muscle atrophy in mice. PMID:20544339

  19. 26 CFR 1.642(a)(1)-1 - Partially tax-exempt interest.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Partially tax-exempt interest. 1.642(a)(1)-1 Section 1.642(a)(1)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Estates, Trusts, and Beneficiaries § 1.642(a)(1)-1 Partially...

  20. FABP1 in wonderland.

    PubMed

    Prinetti, Alessandro; Mitro, Nico

    2016-08-01

    Cannabinoid receptors hold a core position in the brain and control memory, cognition, movement, and pain sensitivity. sn-2 arachidonoylglycerol (2-AG) activates neuronal cannabinoid receptors as a full agonist. The brain may rely on circulating arachidonic acid to synthesize endogenous cannabinoids. This Editorial highlights a study by Martin and coworkers in the current issue of the Journal of Neurochemistry in which the authors describe, for the first time, that liver acts as a pool of arachidonic acid that under certain conditions feeds the brain to produce endocannabinoids. Therapeutics affecting liver FABP1 levels should take into account that FABP1 represents a fatty acid reservoirs for the brain. Read the highlighted article "FABP-1 gene ablation impacts brain endocannabinoid system in male mice" on page 407. PMID:27329821

  1. ATLAS-1 Logo

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The primary payload for the Space Shuttle mission STS-45, launched March 24, 1992, was the Atmospheric Laboratory for Applications and Science-1 (ATLAS-1)which was mounted on nondeployable Spacelab pallets in the orbiter cargo bay. Eight countries, th U.S., France, Germany, Belgium, United Kingdom, Switzerland, The Netherlands, and Japan, provided 12 instruments designed to perform 14 investigations in four fields. Atmospheric science instruments/investigations: Atmospheric Lyman-Alpha Emissions (ALAE); Atmospheric Trace Molecule Spectroscopy (ATMOS); Grille Spectrometer (GRILLE); Imaging Spectrometric Observatory (ISO); Millimeter-Wave Atmospheric Sounder (MAS). Solar Science: Active Cavity Radiometer Irradiance Monitor (ACRIM); Measurement of the Solar Constant (SOLCON); Solar Spectrum from 180 to 3,200 Nanometers (SOLSPEC); Solar Ultraviolet Spectral Irradiance Monitor (SUSIM). Space Plasma Physics: Atmospheric Emissions Photometric Imaging (AEPI); Space Experiments with Particle Accelerators (SEPAC). Ultraviolet astronomy: Far Ultraviolet Space Telescope (FAUST). This is the logo or emblem that was designed to represent the ATLAS-1 payload.

  2. Preparation of 1,1'-dinitro-3,3'-azo-1,2,4-triazole. [1,1'-dinitro-3,3'-azo-1,2,4-triazole

    DOEpatents

    Lee, K.Y.

    1985-03-05

    A new high density composition of matter, 1,1'-dinitro-3,3'-azo-1,2,4-triazole, has been synthesized using inexpensive, commonly available compounds. This compound has been found to be an explosive, and its use as a propellant is anticipated. 1 fig., 1 tab.

  3. Anguillid herpesvirus 1 transcriptome.

    PubMed

    van Beurden, Steven J; Gatherer, Derek; Kerr, Karen; Galbraith, Julie; Herzyk, Pawel; Peeters, Ben P H; Rottier, Peter J M; Engelsma, Marc Y; Davison, Andrew J

    2012-09-01

    We used deep sequencing of poly(A) RNA to characterize the transcriptome of an economically important eel virus, anguillid herpesvirus 1 (AngHV1), at a stage during the lytic life cycle when infectious virus was being produced. In contrast to the transcription of mammalian herpesviruses, the overall level of antisense transcription from the 248,526-bp genome was low, amounting to only 1.5% of transcription in predicted protein-coding regions, and no abundant, nonoverlapping, noncoding RNAs were identified. RNA splicing was found to be more common than had been anticipated previously. Counting the 10,634-bp terminal direct repeat once, 100 splice junctions were identified, of which 58 were considered likely to be involved in the expression of functional proteins because they represent splicing between protein-coding exons or between 5' untranslated regions and protein-coding exons. Each of the 30 most highly represented of these 58 splice junctions was confirmed by RT-PCR. We also used deep sequencing to identify numerous putative 5' and 3' ends of AngHV1 transcripts, confirming some and adding others by rapid amplification of cDNA ends (RACE). The findings prompted a revision of the AngHV1 genome map to include a total of 129 protein-coding genes, 5 of which are duplicated in the terminal direct repeat. Not counting duplicates, 11 genes contain integral, spliced protein-coding exons, and 9 contain 5' untranslated exons or, because of alternative splicing, 5' untranslated and 5' translated exons. The results of this study sharpen our understanding of AngHV1 genomics and provide the first detailed view of a fish herpesvirus transcriptome. PMID:22787220

  4. IO SUBSYSTEM 1 BETA

    2002-08-21

    "IO Subsystem Ver. 1.0 Beta" uses standard object-oriented principles to minimize dependencies between the underlying input or output database format and the client code (i.e., Sierra) using the io subsystem. The interface and priciples are simolar to the Facade pattern described in the "Design Patterns" book by Gamma, et.al. The software uses data authentication algorithms to ensure data input/output is consistent with model being defined. "IO Subsystem Ver. 1.0 Beta" is a database independent input/outputmore » library for finite element analysis, preprocessing, post processing, and translation programs.« less

  5. Dark U (1)

    NASA Astrophysics Data System (ADS)

    Chang, Chia-Feng; Ma, Ernest; Yuan, Tzu-Chiang

    2015-06-01

    In this talk we will explore the possibility of adding a local U(1) dark sector to the standard model with the Higgs boson as a portal connecting the visible standard model sector and the dark one. We will discuss existing experimental constraint on the model parameters from the invisible width of Higgs decay. Implications of such a dark U(1) sector on phenomenology at the Large Hardon Collider will be addressed. In particular, detailed results for the non-standard signals of multi-lepton-jets that arise from this simple dark sector will be presented.

  6. [Vitamin B1 (thiamine)].

    PubMed

    Guilland, Jean-Claude

    2013-10-01

    Vitamin B1 (or thiamine) plays a key role in energy production from glucose. Since the main fuel of the nervous system is glucose, thiamine deficiency causes severe neurological symptoms. The biological exploration of vitamin B1 status is based on the measurement of thiamine pyrophosphate concentration or of the activity of a thiamine-dependent enzyme, transketolase, in erythrocytes. Severe deficiency states can be observed in chronic alcoholics, after protracted vomiting during pregnancy and after bariatric surgery. Mild deficiencies are common in the general population, but their clinical consequences are still unclear. PMID:24298824

  7. IO SUBSYSTEM 1 BETA

    SciTech Connect

    Sjaardema, Greg

    2002-08-21

    "IO Subsystem Ver. 1.0 Beta" uses standard object-oriented principles to minimize dependencies between the underlying input or output database format and the client code (i.e., Sierra) using the io subsystem. The interface and priciples are simolar to the Facade pattern described in the "Design Patterns" book by Gamma, et.al. The software uses data authentication algorithms to ensure data input/output is consistent with model being defined. "IO Subsystem Ver. 1.0 Beta" is a database independent input/output library for finite element analysis, preprocessing, post processing, and translation programs.

  8. S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness

    PubMed Central

    Chavez, Alejandra; Schmidt, Tracy Thennes; Yazbeck, Pascal; Rajput, Charu; Desai, Bhushan; Sukriti, Sukriti; Giantsos-Adams, Kristina; Knezevic, Nebojsa; Malik, Asrar B.; Mehta, Dolly

    2015-01-01

    ABSTRACT Activation of sphingosine-1-phosphate receptor 1 (S1PR1) plays a key role in repairing endothelial barrier function. We addressed the role of phosphorylation of the three intracellular tyrosine residues of S1PR1 in endothelial cells in regulating the receptor responsiveness and endothelial barrier function regulated by sphingosine 1-phosphate (S1P)-mediated activation of S1PR1. We demonstrated that phosphorylation of only Y143 site was required for S1PR1 internalization in response to S1P. Maximal S1PR1 internalization was seen in 20 min but S1PR1 returned to the cell surface within 1 h accompanied by Y143-dephosphorylation. Cell surface S1PR1 loss paralleled defective endothelial barrier enhancement induced by S1P. Expression of phospho-defective (Y143F) or phospho-mimicking (Y143D) mutants, respectively, failed to internalize or showed unusually high receptor internalization, consistent with the requirement of Y143 in regulating cell surface S1PR1 expression. Phosphorylation of the five S1PR1 C-terminal serine residues did not affect the role of Y143 phosphorylation in signaling S1PR1 internalization. Thus, rapid reduction of endothelial cell surface expression of S1PR1 subsequent to Y143 phosphorylation is a crucial mechanism of modulating S1PR1 signaling, and hence the endothelial barrier repair function of S1P. PMID:25588843

  9. Involvement of sphingosine-1-phosphate and S1P1 in angiogenesis: analyses using a new S1P1 antagonist of non-sphingosine-1-phosphate analog.

    PubMed

    Yonesu, Kiyoaki; Kawase, Yumi; Inoue, Tatsuya; Takagi, Nana; Tsuchida, Jun; Takuwa, Yoh; Kumakura, Seiichiro; Nara, Futoshi

    2009-03-15

    Chemical lead 2 (CL2) is the first non-sphingosine-1-phosphate (Sph-1-P) analog type antagonist of endothelial differentiation gene-1 (Edg-1/S1P(1)), which is a member of the Sph-1-P receptor family. CL2 inhibits [(3)H]Sph-1-P/S1P(1) binding and shows concentration-dependent inhibition activity against both intracellular cAMP concentration decrease and cell invasion induced by the Sph-1-P/S1P(1) pathway. It also inhibits normal tube formation in an angiogenesis culture model, indicating that CL2 has anti-angiogenesis activity. This compound improved the disease conditions in two angiogenic models in vivo. It significantly inhibited angiogenesis induced by vascular endothelial growth factor in a rabbit cornea model as well as the swelling of mouse feet in an anti-type II collagen antibody-induced arthritis model. These results indicate that the Sph-1-P/S1P(1) pathway would have an important role in disease-related angiogenesis, especially in the processes of migration/invasion and tube formation. In addition, CL2 would be a powerful tool for the pharmacological study of the mechanisms of the Sph-1-P/S1P(1) pathway in rheumatoid arthritis, diabetes retinopathy, and solid tumor growth processes. PMID:19150609

  10. Spacelab-1 Module

    NASA Technical Reports Server (NTRS)

    1983-01-01

    This photograph shows the Spacelab-1 module and Spacelab access turnel being installed in the cargo bay of orbiter Columbia for the STS-9 mission. The oribiting laboratory, built by the European Space Agency, is capable of supporting many types of scientific research that can best be performed in space. The Spacelab access tunnel, the only major piece of Spacelab hardware made in the U.S., connects the module with the mid-deck level of the orbiter cabin. The first Spacelab mission, Spacelab-1, sponsored jointly and shared equally by NASA and the European Space Agency, was a multidisciplinary mission; that is, investigations were performed in several different fields of scientific research. The overall goal of the mission was to verify Spacelab performance through a variety of scientific experiments. The disciplines represented by these experiments were: astronomy and solar physics, earth observations, space plasma physics, materials sciences, atmospheric physics, and life sciences. International in nature, Spacelab-1 conducted experiments from the United States, Japan, the Netherlands, United Kingdom, Beluga, France, Germany, Italy, and Switzerland. Spacelab-1, was launched from the Kennedy Space Center on November 28, 1983 aboard the orbiter Columbia (STS-9). The Marshall Space Flight Center was responsible for managing the Spacelab missions.

  11. Pharmacogenetics of OPRM1.

    PubMed

    Crist, Richard C; Berrettini, Wade H

    2014-08-01

    Pharmacogenetic research has the potential to explain the variation in treatment efficacy within patient populations. Understanding the interaction between genetic variation and medications may provide a method for matching patients to the most effective therapeutic options and improving overall patient outcomes. The OPRM1 gene has been a target of interest in a large number of pharmacogenetic studies due to its genetic and structural variation, as well as the role of opioid receptors in a variety of disorders. The mu-opioid receptor (MOR), encoded by OPRM1, naturally regulates the analgesic response to pain and also controls the rewarding effects of many drugs of abuse, including opioids, nicotine, and alcohol. Genetic variants in OPRM1, particularly the non-synonymous polymorphism A118G, have been repeatedly associated with the efficacy of treatments for pain and various types of dependence. This review focuses on the current understanding of the pharmacogenetic impact of OPRM1, primarily with regard to the treatment of pain and addiction. PMID:24201053

  12. Pharmacogenetics of OPRM1

    PubMed Central

    Crist, Richard C.; Berrettini, Wade H.

    2013-01-01

    Pharmacogenetic research has the potential to explain the variation in treatment efficacy within patient populations. Understanding the interaction between genetic variation and medications may provide a method for matching patients to the most effective therapeutic options and improving overall patient outcomes. The OPRM1 gene has been a target of interest in a large number of pharmacogenetic studies due to its genetic and structural variation, as well as the role of opioid receptors in a variety of disorders. The mu-opioid receptor (MOR), encoded by OPRM1, naturally regulates the analgesic response to pain and also controls the rewarding effects of many drugs of abuse, including opioids, nicotine, and alcohol. Genetic variants in OPRM1, particularly the nonsynonymous polymorphism A118G, have been repeatedly associated with the efficacy of treatments for pain and various types of dependence. This review focuses on the current understanding of the pharmacogenetic impact of OPMR1, primarily in regards to the treatment of pain and addiction. PMID:24201053

  13. The Remarkable Number "1"

    ERIC Educational Resources Information Center

    Allen, G. Donald

    2014-01-01

    In human history, the origin of the numbers came from definite practical needs. Indeed, there is strong evidence that numbers were created before writing. The number "1", dating back at least 20,000 years, was found as a counting symbol on a bone. The famous statement by the German mathematician Leopold Kronecker (1823-1891), "God…

  14. CLE Working Papers 1.

    ERIC Educational Resources Information Center

    Southampton Univ. (England). Centre for Language Education.

    The purpose of these working papers is to reflect the current activities of members of the Centre for Language in Education at the University of Southampton, England. They include: (1) "Inaugural Lecture: Is Language Education or Is Education Language?" (Christopher Brumfit); (2) "Teachers' Views of Language Knowledge" (Rosamond Mitchell and Janet…

  15. 1,2-Dichloroethane

    Integrated Risk Information System (IRIS)

    1,2 - Dichloroethane ; CASRN 107 - 06 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge

  16. 1,3-Butadiene

    Integrated Risk Information System (IRIS)

    1,3 - Butadiene ; CASRN 106 - 99 - 0 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic E

  17. Avermectin B1

    Integrated Risk Information System (IRIS)

    Avermectin B1 ; CASRN 65195 - 55 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic E

  18. 1,4-Dibromobenzene

    Integrated Risk Information System (IRIS)

    1,4 - Dibromobenzene ; CASRN 106 - 37 - 6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge

  19. 1,4-Dichlorobenzene

    Integrated Risk Information System (IRIS)

    1,4 - Dichlorobenzene ; CASRN 106 - 46 - 7 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinog

  20. 1,2-Dichloropropane

    Integrated Risk Information System (IRIS)

    1,2 - Dichloropropane ; CASRN 78 - 87 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge