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Sample records for 1-2 km wide

  1. Faraday laser using 1.2 km fiber as an extended cavity

    NASA Astrophysics Data System (ADS)

    Tao, Zhiming; Zhang, Xiaogang; Pan, Duo; Chen, Mo; Zhu, Chuanwen; Chen, Jingbiao

    2016-07-01

    We demonstrate a Faraday laser using a 1.2 km fiber as an extended cavity, which provides optical feedback and obtains small free spectrum range (FSR) of 83 kHz, and have succeeded in limiting the laser frequency to a crossover transition {5}2{S}1/2,F=2\\to {5}2{P}3/2,F\\prime =1,3 of the natural 87Rb at 780 nm. The Faraday laser is based on a Faraday anomalous dispersion optical filter (FADOF) with an ultra-narrow bandwidth and the long fiber extended cavity of 1.2 km. The peak transmission assigned to the crossover transition F=2\\to F\\prime =1,3 in the FADOF is 20.5% with an ultra-narrow bandwidth of 29.1 MHz. The Allan deviation of the Faraday laser is around 6.0× {10}-11 in 0.06 to 1 s sampling time. Laser frequency is always kept in the center of the transmitted peak assigned to F=2\\to F\\prime =1,3. The Faraday laser realized here can provide light exactly resonant with an atomic transition used for atom-photon interaction experiments and is insensitive to diode temperature and injection current fluctuations.

  2. Faraday laser using 1.2 km fiber as an extended cavity

    NASA Astrophysics Data System (ADS)

    Tao, Zhiming; Zhang, Xiaogang; Pan, Duo; Chen, Mo; Zhu, Chuanwen; Chen, Jingbiao

    2016-07-01

    We demonstrate a Faraday laser using a 1.2 km fiber as an extended cavity, which provides optical feedback and obtains small free spectrum range (FSR) of 83 kHz, and have succeeded in limiting the laser frequency to a crossover transition {5}2{S}1/2,F=2\\to {5}2{P}3/2,F\\prime =1,3 of the natural 87Rb at 780 nm. The Faraday laser is based on a Faraday anomalous dispersion optical filter (FADOF) with an ultra-narrow bandwidth and the long fiber extended cavity of 1.2 km. The peak transmission assigned to the crossover transition F=2\\to F\\prime =1,3 in the FADOF is 20.5% with an ultra-narrow bandwidth of 29.1 MHz. The Allan deviation of the Faraday laser is around 6.0× {10}-11 in 0.06 to 1 s sampling time. Laser frequency is always kept in the center of the transmitted peak assigned to F=2\\to F\\prime =1,3. The Faraday laser realized here can provide light exactly resonant with an atomic transition used for atom–photon interaction experiments and is insensitive to diode temperature and injection current fluctuations.

  3. High cesium concentrations in groundwater in the upper 1.2 km of fractured crystalline rock - Influence of groundwater origin and secondary minerals

    NASA Astrophysics Data System (ADS)

    Mathurin, Frédéric A.; Drake, Henrik; Tullborg, Eva-Lena; Berger, Tobias; Peltola, Pasi; Kalinowski, Birgitta E.; Åström, Mats E.

    2014-05-01

    Dissolved and solid phase cesium (Cs) was studied in the upper 1.2 km of a coastal granitoid fracture network on the Baltic Shield (Äspö Hard Rock Laboratory and Laxemar area, SE Sweden). There unusually high Cs concentrations (up to 5-6 μg L-1) occur in the low-temperature (<20 °C) groundwater. The material includes water collected in earlier hydrochemical monitoring programs and secondary precipitates (fracture coatings) collected on the fracture walls, as follows: (a) hydraulically pristine fracture groundwater sampled through 23 surface boreholes equipped for the retrieval of representative groundwater at controlled depths (Laxemar area), (b) fracture groundwater affected by artificial drainage collected through 80 boreholes drilled mostly along the Äspö Hard Rock Laboratory (underground research facility), (c) surface water collected in local streams, a lake and sea bay, and shallow groundwater collected in 8 regolith boreholes, and (d) 84 new specimens of fracture coatings sampled in cores from the Äspö HRL and Laxemar areas. The groundwater in each area is different, which affects Cs concentrations. The highest Cs concentrations occurred in deep-seated saline groundwater (median Äspö HRL: 4.1 μg L-1; median Laxemar: 3.7 μg L-1) and groundwater with marine origin (Äspö HRL: 4.2 μg L-1). Overall lower, but variable, Cs concentrations were found in other types of groundwater. The similar concentrations of Cs in the saline groundwater, which had a residence time in the order of millions of years, and in the marine groundwater, which had residence times in the order of years, shows that duration of water-rock interactions is not the single and primary control of dissolved Cs in these systems. The high Cs concentrations in the saline groundwater is ascribed to long-term weathering of minerals, primarily Cs-enriched fracture coatings dominated by illite and mixed-layer clays and possibly wall rock micaceous minerals. The high Cs concentrations in the

  4. WIDE RANGE ACHIEVEMENT TEST IN AUTISM SPECTRUM DISORDER: TEST-RETEST STABILITY1, 2, 3

    PubMed Central

    JANTZ, PAUL B.; FROEHLICH, ALYSON L.; CARIELLO, ANNAHIR N.; ANDERSON, JEFFREY; ALEXANDER, ANDREW L.; BIGLER, ERIN D.; PRIGGE, MOLLY B. D.; TRAVERS, BRITTANY G.; ZIELINSKI, BRANDON A.; LANGE, NICHOLAS; LAINHART, JANET E.

    2015-01-01

    Summary The principal goal of this descriptive study was to establish the test-retest stability of the Reading, Spelling, and Arithmetic subtest scores of the Wide Range Achievement Test (WRAT–3) across two administrations in individuals with autism spectrum disorder. Participants (N=31) were males ages 6–22years (M=15.2, SD=4.0) who were part of a larger ongoing longitudinal study of brain development in children and adults with autism spectrum disorder (N=185). Test-retest stability for all three subtests remained consistent across administration periods (M=31.8mo., SD=4.1). Age at time of administration, time between administrations, and test form did not significantly influence test-retest stability. Results indicated that for research involving individuals with autism spectrum disorder with a full scale intelligence quotient above 75, the WRAT–3 Spelling and Arithmetic subtests have acceptable test-retest stability over time and the Reading subtest has moderate test-retest stability over time. PMID:25871566

  5. Galaxy clustering in the CFHTLS-Wide: the changing relationship between galaxies and haloes since z ~ 1.2

    NASA Astrophysics Data System (ADS)

    Coupon, J.; Kilbinger, M.; McCracken, H. J.; Ilbert, O.; Arnouts, S.; Mellier, Y.; Abbas, U.; de la Torre, S.; Goranova, Y.; Hudelot, P.; Kneib, J.-P.; Le Fèvre, O.

    2012-06-01

    It has become increasingly apparent that studying how dark matter haloes are populated by galaxies can provide new insights into galaxy formation and evolution. In this paper, we present a detailed investigation of the changing relationship between galaxies and the dark matter haloes they inhabit from z ~ 1.2 to the present day. We do this by comparing precise galaxy clustering measurements over 133 deg2 of the "Wide" component of the Canada-France-Hawaii Telescope Legacy Survey (CFHTLS) with predictions of an analytic halo occupation distribution (HOD) model where the number of galaxies in each halo depends only on the halo mass. Starting from a parent catalogue of ~3 × 106 galaxies at i'AB<22.5 we use accurate photometric redshifts calibrated using ~104 spectroscopic redshifts to create a series of type-selected volume-limited samples covering 0.2 < z < 1.2. Our principal result, based on clustering measurements in these samples, is a robust determination of the luminosity-to-halo mass ratio and its dependence on redshift and galaxy type. For the full sample, this reaches a peak at low redshifts of Mhpeak = 4.5×1011 h-1 M⊙ and moves towards higher halo masses at higher redshifts. For redder galaxies the peak is at higher halo masses and does not evolve significantly over the entire redshift range of our survey. We also consider the evolution of bias, average halo mass and the fraction of satellites as a function of redshift and luminosity. Our observed growth of a factor of ~2 in satellite fraction between z ~ 1 and z ~ 0 is testament to the limited role that galaxy merging plays in galaxy evolution for ~1012 h-1 M⊙ mass haloes at z < 1. Qualitatively, our observations are consistent with a picture in which red galaxies in massive haloes have already accumulated most of their stellar mass by z ~ 1 and subsequently undergo little evolution until the present day. The observed movement of the peak location for the full galaxy population is consistent with the

  6. Analysis of the Herschel/HIFI 1.2 THz Wide Spectral Survey of the Orion Kleinmann-Low Nebula

    NASA Astrophysics Data System (ADS)

    Crockett, Nathan R.

    This dissertation presents a comprehensive analysis of a broad band spectral line survey of the Orion Kleinmann-Low nebula (Orion KL), one of the most chemically rich regions in the Galaxy, using the HIFI instrument on board the Herschel Space Observatory. This survey spans a frequency range from 480 to 1907 GHz at a resolution of 1.1 MHz. These observations thus encompass the largest spectral coverage ever obtained toward this massive star forming region in the sub-mm with high spectral resolution, and include frequencies >1 THz where the Earth's atmosphere prevents observations from the ground. In all, we detect emission from 36 molecules (76 isotopologues). Combining this dataset with ground based mm spectroscopy obtained with the IRAM 30 m telescope, we model the molecular emission assuming local thermodynamic equilibrium (LTE). Because of the wide frequency coverage, our models are constrained over an unprecedented range in excitation energy, including states at or close to ground up to energies where emission is no longer detected. A χ2 analysis indicates that most of our models reproduce the observed emission well. In particular complex organics, some with thousands of transitions, are well fit by LTE models implying that gas densities are high (>10^6 cm^-3) and excitation temperatures and column densities are well constrained. Molecular abundances are computed using H2 column densities also derived from the HIFI survey. The rotation temperature distribution of molecules detected toward the hot core is much wider relative to the compact ridge, plateau, and extended ridge. We find that complex N-bearing species, cyanides in particular, systematically probe hotter gas than complex O-bearing species. This indicates complex N-bearing molecules may be more difficult to remove from grain surfaces or that hot gas phase formation routes are important for these species. We also present a detailed non-LTE analysis of H2S emission toward the hot core which suggests

  7. Open-System Magma Reservoir Affects Gas Segregation, Vesiculation, Fragmentation and Lava/Pyroclast Dispersal During the 1.2 km-deep 2007-2010 Submarine Eruption at West Mata Volcano

    NASA Astrophysics Data System (ADS)

    Rubin, K. H.; Clague, D. A.; Embley, R. W.; Hellebrand, E.; Soule, S. A.; Resing, J.

    2014-12-01

    West Mata, a small, active rear-arc volcano in the NE Lau Basin, erupts crystal and gas rich boninite magma. Eruptions were observed at the summit (1.2 km water depth) during 5 ROV Jason dives in 2009 (the deepest erupting submarine volcano observed to date). Subsequent ROV and ship-based bathymetric mapping revealed that a pit crater formed and the summit eruption ceased in 2010, with roughly simultaneous eruptions along the SW rift zone. During the summit eruption, a combination of water depth, H2O-CO2-rich and high crystallinity magma, a split in the conduit to feed two vent sites, and waxing/waning magma supply led to a range of effusive/explosive eruption styles and volcanic deposit types. The 2-3 vent Hades cluster and the lone Prometheus vent had different eruption characteristics. Petrographic, petrologic and geochemical studies of erupted products indicate a change in magma composition in time and space over a period of 3.5 yrs, suggesting a small, open-system magma reservoir within the volcano. Prometheus (1174m depth) produced mostly pyroclastic material during our observations (e.g., highly vesicular glowing fluidal ejecta that cooled in the water column and rounded recycled dense clasts), but sampling and 210Po radiometric dating show that several months prior pillowed lava flows, subsequently covered with cm-sized pyroclasts, had flowed >50m from the vent. In contrast, vents at Hades (1200m depth) cycled between lava production and vigorous degassing, 10-20m high fire fountains and bursts of glowing lava-skinned bubbles, the products of which froze/broke in the water column, forming unstable cones of spatter and scoria near the vents. We hypothesize that bubbles collapse rather than form lava balloons because of skin brittleness (from high crystal content) and hydrostatic pressure. Clast settling times and patterns suggest >100m water column rise height for 10+ cm-sized fragments. Pillow flows were also observed to be issuing from the base of the

  8. Reviving the African wolf Canis lupus lupaster in North and West Africa: a mitochondrial lineage ranging more than 6,000 km wide.

    PubMed

    Gaubert, Philippe; Bloch, Cécile; Benyacoub, Slim; Abdelhamid, Adnan; Pagani, Paolo; Djagoun, Chabi Adéyèmi Marc Sylvestre; Couloux, Arnaud; Dufour, Sylvain

    2012-01-01

    The recent discovery of a lineage of gray wolf in North-East Africa suggests the presence of a cryptic canid on the continent, the African wolf Canis lupus lupaster. We analyzed the mtDNA diversity (cytochrome b and control region) of a series of African Canis including wolf-like animals from North and West Africa. Our objectives were to assess the actual range of C. l. lupaster, to further estimate the genetic characteristics and demographic history of its lineage, and to question its taxonomic delineation from the golden jackal C. aureus, with which it has been considered synonymous. We confirmed the existence of four distinct lineages within the gray wolf, including C. lupus/familiaris (Holarctic wolves and dogs), C. l. pallipes, C. l. chanco and C. l. lupaster. Taxonomic assignment procedures identified wolf-like individuals from Algeria, Mali and Senegal, as belonging to C. l. lupaster, expanding its known distribution c. 6,000 km to the west. We estimated that the African wolf lineage (i) had the highest level of genetic diversity within C. lupus, (ii) coalesced during the Late Pleistocene, contemporaneously with Holarctic wolves and dogs, and (iii) had an effective population size of c. 80,000 females. Our results suggest that the African wolf is a relatively ancient gray wolf lineage with a fairly large, past effective population size, as also suggested by the Pleistocene fossil record. Unique field observations in Senegal allowed us to provide a morphological and behavioral diagnosis of the African wolf that clearly distinguished it from the sympatric golden jackal. However, the detection of C. l. lupaster mtDNA haplotypes in C. aureus from Senegal brings the delineation between the African wolf and the golden jackal into question. In terms of conservation, it appears urgent to further characterize the status of the African wolf with regard to the African golden jackal. PMID:22900047

  9. Reviving the African Wolf Canis lupus lupaster in North and West Africa: A Mitochondrial Lineage Ranging More than 6,000 km Wide

    PubMed Central

    Gaubert, Philippe; Bloch, Cécile; Benyacoub, Slim; Abdelhamid, Adnan; Pagani, Paolo; Djagoun, Chabi Adéyèmi Marc Sylvestre; Couloux, Arnaud; Dufour, Sylvain

    2012-01-01

    The recent discovery of a lineage of gray wolf in North-East Africa suggests the presence of a cryptic canid on the continent, the African wolf Canis lupus lupaster. We analyzed the mtDNA diversity (cytochrome b and control region) of a series of African Canis including wolf-like animals from North and West Africa. Our objectives were to assess the actual range of C. l. lupaster, to further estimate the genetic characteristics and demographic history of its lineage, and to question its taxonomic delineation from the golden jackal C. aureus, with which it has been considered synonymous. We confirmed the existence of four distinct lineages within the gray wolf, including C. lupus/familiaris (Holarctic wolves and dogs), C. l. pallipes, C. l. chanco and C. l. lupaster. Taxonomic assignment procedures identified wolf-like individuals from Algeria, Mali and Senegal, as belonging to C. l. lupaster, expanding its known distribution c. 6,000 km to the west. We estimated that the African wolf lineage (i) had the highest level of genetic diversity within C. lupus, (ii) coalesced during the Late Pleistocene, contemporaneously with Holarctic wolves and dogs, and (iii) had an effective population size of c. 80,000 females. Our results suggest that the African wolf is a relatively ancient gray wolf lineage with a fairly large, past effective population size, as also suggested by the Pleistocene fossil record. Unique field observations in Senegal allowed us to provide a morphological and behavioral diagnosis of the African wolf that clearly distinguished it from the sympatric golden jackal. However, the detection of C. l. lupaster mtDNA haplotypes in C. aureus from Senegal brings the delineation between the African wolf and the golden jackal into question. In terms of conservation, it appears urgent to further characterize the status of the African wolf with regard to the African golden jackal. PMID:22900047

  10. Magnetocaloric effect over a wide temperature range due to multiple magnetic transitions in GdNi0.8Al1.2 alloy

    NASA Astrophysics Data System (ADS)

    Rashid, T. P.; Nallamuthu, S.; Arun, K.; Curlik, Ivan; Ilkovic, Sergej; Dzubinska, Andrea; Reiffers, Marian; Nagalakshmi, R.

    2016-05-01

    The magnetic properties, magnetocaloric effect (MCE) and refrigerant capacity (RC) of the novel polycrystalline GdNi0.8Al1.2 alloy are investigated. The temperature dependence of magnetization exhibits multiple magnetic transitions at T1=17.7 K, T2=46.7 K and T3=256 K thereby displaying a complex magnetic behaviour. The magnetocaloric effect is calculated in terms of the magnetic entropy change ( -Δ SM), from isothermal magnetization data using Maxwell relations. The maximum magnetic entropy change at major transitions T2 is 9.15 J kg-1K-1 (for a field change of 0-9 T) and 4.20 Jkg-1K-1 (0-5 T) and at T3 is 1.10 Jkg-1K-1 (0-9 T) and 0.67 Jkg-1K-1 (0-5 T). The overlap of the two -Δ SM peaks expeditiously expand the working temperature range of this material with substantial MCE which in turn yields moderate RC value of 120 J/kg for a field change of 0-5T. These results suggest that the GdNi0.8Al1.2 alloy may be a meaningful candidate for magnetic refrigeration working in a wide temperature range.

  11. Evolution of colour-dependence of galaxy clustering up to z˜ 1.2 based on the data from the VVDS-Wide survey

    NASA Astrophysics Data System (ADS)

    Świetoń, Agnieszka; Pollo, Agnieszka; VVDS Team

    2014-12-01

    We discuss the dependence of galaxy clustering according to their colours up to z˜ 1.2. For that purpose we used one of the wide fields (F22) from the VIMOS-VLT Deep Survey (VVDS). For galaxies with absolute luminosities close to the characteristic Schechter luminosities M^* at a given redshift, we measured the projected two-point correlation function w_{p}(r_{p}) and we estimated the best-fit parameters for a single power-law model: ξ(r) = (r/r_0)^{-γ} , where r_0 is the correlation length and γ is the slope of correlation function. Our results show that red galaxies exhibit the strongest clustering in all epochs up to z˜ 1.2. Green valley represents the "intermediate" population and blue cloud shows the weakest clustering strength. We also compared the shape of w_p(r_p) for different galaxy populations. All three populations have different clustering properties on the small scales, similarly to the behaviour observed in the local catalogues.

  12. Genome-wide analysis and identification of stress-responsive genes of the NAM-ATAF1,2-CUC2 transcription factor family in apple.

    PubMed

    Su, Hongyan; Zhang, Shizhong; Yuan, Xiaowei; Chen, Changtian; Wang, Xiao-Fei; Hao, Yu-Jin

    2013-10-01

    NAC (NAM, ATAF1,2, and CUC2) proteins constitute one of the largest families of plant-specific transcription factors. To date, little is known about the NAC genes in the apple (Malus domestica). In this study, a total of 180 NAC genes were identified in the apple genome and were phylogenetically clustered into six groups (I-VI) with the NAC genes from Arabidopsis and rice. The predicted apple NAC genes were distributed across all of 17 chromosomes at various densities. Additionally, the gene structure and motif compositions of the apple NAC genes were analyzed. Moreover, the expression of 29 selected apple NAC genes was analyzed in different tissues and under different abiotic stress conditions. All of the selected genes, with the exception of four genes, were expressed in at least one of the tissues tested, which indicates that the NAC genes are involved in various aspects of the physiological and developmental processes of the apple. Encouragingly, 17 of the selected genes were found to respond to one or more of the abiotic stress treatments, and these 17 genes included not only the expected 7 genes that were clustered with the well-known stress-related marker genes in group IV but also 10 genes located in other subgroups, none of which contains members that have been reported to be stress-related. To the best of our knowledge, this report describes the first genome-wide analysis of the apple NAC gene family, and the results should provide valuable information for understanding the classification and putative functions of this family.

  13. Imaging Resolution of the 410-km and 660-km Discontinuities

    NASA Astrophysics Data System (ADS)

    Deng, K.; Zhou, Y.

    2014-12-01

    Structure of seismic discontinuities at depths of about 410 km and 660 km provides important constraints on mantle convection as the associated phase transformations in the transition zone are sensitive to thermal perturbations. Teleseismic P-to-S receiver functions have been widely used to map the depths of the two discontinuities. In this study, we investigate the resolution of receiver functions in imaging topographic variations of the 410-km and 660-km discontinuities based on wave propagation simulations using the Spectral Element Method (SEM). We investigate finite-frequency effects of direct P waves as well as P-to-S converted waves by varying the length scale of discontinuity topography in the transition zone. We show that wavefront healing effects are significant in broadband receiver functions. For example, at a period of 10 to 20 seconds, the arrival anomaly in P-to-S converted waves is about 50% of what predicted by ray theory when the topography length scale is in the order of 400 km. The observed arrival anomaly further reduces to 10-20% when the topography length scale reduces to about 200 km. We calculate 2-D boundary sensitivity kernels for direct P waves as well as receiver functions based on surface wave mode summation and confirm that finite frequency-effects can be properly accounted for. Three-dimensional wavespeed structure beneath seismic stations can also introduce significant artifacts in transition zone discontinuity topography if time corrections are not applied, and, the effects are dependent on frequency.

  14. Genome wide identification of C1-2i zinc finger proteins and their response to abiotic stress in hexaploid wheat.

    PubMed

    Cheuk, Arnaud; Houde, Mario

    2016-04-01

    The C1-2i wheat Q-type C2H2 zinc finger protein (ZFP) transcription factor subclass has been reported to play important roles in plant stress responses. This subclass of ZFPs has not been studied in hexaploid wheat (Triticum aestivum) and we aimed to identify all members of this subclass and evaluate their responses to different abiotic stresses causing oxidative stress. Exploiting the recently published wheat draft genome sequence, we identified 53 members (including homoeologs from A, B and D genomes) of the C1-2i wheat Q-type C2H2 ZFPs (TaZFPs) representing 21 genes. Evolution analysis revealed that 9 TaZFPs members are directly inherited from the parents Triticum urartu and Aegilops tauschii, while 15 diverged through neoploidization events. This TaZFP subclass is responsive to the oxidative stress generator H2O2 and to high light, drought stress and flooding. Most TaZFPs are responsive to H2O2 (37/53), high light (44/53), flooding (31/53) or drought (37/53); 32 TaZFPs were up-regulated by at least 3 stresses and 16 were responsive to all stresses tested. A large number of these TaZFPs were physically mapped on different wheat draft genome sequences with known markers useful for QTL mapping. Our results show that the C1-2i subclass of TaZFPs is associated with responses to different abiotic stresses and that most TaZFPs (30/53 or 57 %) are located on group 5 chromosomes known to be involved in environment adaptation. Detailed characterization of these novel wheat TaZFPs and their association to QTL or eQTL may help to design wheat cultivars with improved tolerance to abiotic stress.

  15. Evidence for wide-spread active galactic nucleus-driven outflows in the most massive z ∼ 1-2 star-forming galaxies

    SciTech Connect

    Genzel, R.; Förster Schreiber, N. M.; Rosario, D.; Lang, P.; Lutz, D.; Wisnioski, E.; Wuyts, E.; Wuyts, S.; Bandara, K.; Bender, R.; Berta, S.; Kurk, J.; Mendel, J. T.; Tacconi, L. J.; Wilman, D.; Beifiori, A.; Burkert, A.; Buschkamp, P.; Chan, J.; Brammer, G. E-mail: genzel@mpe.mpg.de; and others

    2014-11-20

    In this paper, we follow up on our previous detection of nuclear ionized outflows in the most massive (log(M {sub *}/M {sub ☉}) ≥ 10.9) z ∼ 1-3 star-forming galaxies by increasing the sample size by a factor of six (to 44 galaxies above log(M {sub *}/M {sub ☉}) ≥ 10.9) from a combination of the SINS/zC-SINF, LUCI, GNIRS, and KMOS{sup 3D}spectroscopic surveys. We find a fairly sharp onset of the incidence of broad nuclear emission (FWHM in the Hα, [N II], and [S II] lines ∼450-5300 km s{sup –1}), with large [N II]/Hα ratios, above log(M {sub *}/M {sub ☉}) ∼ 10.9, with about two-thirds of the galaxies in this mass range exhibiting this component. Broad nuclear components near and above the Schechter mass are similarly prevalent above and below the main sequence of star-forming galaxies, and at z ∼ 1 and ∼2. The line ratios of the nuclear component are fit by excitation from active galactic nuclei (AGNs), or by a combination of shocks and photoionization. The incidence of the most massive galaxies with broad nuclear components is at least as large as that of AGNs identified by X-ray, optical, infrared, or radio indicators. The mass loading of the nuclear outflows is near unity. Our findings provide compelling evidence for powerful, high-duty cycle, AGN-driven outflows near the Schechter mass, and acting across the peak of cosmic galaxy formation.

  16. Imaging Resolution of 410-km and 660-km Discontinuities

    NASA Astrophysics Data System (ADS)

    Deng, Kai; Zhou, Ying

    2014-05-01

    Seismic discontinuities in the mantle transition zone at depths of about 410 and 660 km are associated with olivine phase transformations. The depths of the discontinuities provide important constraints on the thermal structure of the mid mantle. Teleseismic receiver functions as well as PP and SS precursors have been widely used in imaging topographic variations of the 410 and 660 discontinuities. Ray-theory based migration and stacking methods are often used to enhance signals of the converted and reflected waves, assuming that the effects of 3-D structure in wavespeed can be averaged out. In this study, we investigate the resolution of traditional methods in imaging the 410-km and 660-km discontinuity topography based on wave propagation simulations using the Spectral Element Method (SEM). We calculate synthetic seismograms in laterally heterogeneous wavespeed models with lateral variations in the 410-km and 660-km discontinuity depths. The SEM synthetics are processed following standard migration and stacking techniques to image the discontinuities. We show that 3-D wave speed structure beneath seismic stations can introduce significant artifacts in transition zone discontinuity topography. We also investigate finite-frequency effects of P-to-S converted waves as well as PP and SS precursors in imaging the discontinuities by varying the length scale of depth variations in the 410-km and 660-km discontinuities in SEM simulations, and show that wave front healing effects depend on the length scale of the depth variation as well as epicentral distances. Finally we compare receiver function delay times with calculations based on finite frequency sensitivity and show that wave front healing effects can be properly accounted for.

  17. Evidence for Wide-spread Active Galactic Nucleus-driven Outflows in the Most Massive z ~ 1-2 Star-forming Galaxies

    NASA Astrophysics Data System (ADS)

    Genzel, R.; Förster Schreiber, N. M.; Rosario, D.; Lang, P.; Lutz, D.; Wisnioski, E.; Wuyts, E.; Wuyts, S.; Bandara, K.; Bender, R.; Berta, S.; Kurk, J.; Mendel, J. T.; Tacconi, L. J.; Wilman, D.; Beifiori, A.; Brammer, G.; Burkert, A.; Buschkamp, P.; Chan, J.; Carollo, C. M.; Davies, R.; Eisenhauer, F.; Fabricius, M.; Fossati, M.; Kriek, M.; Kulkarni, S.; Lilly, S. J.; Mancini, C.; Momcheva, I.; Naab, T.; Nelson, E. J.; Renzini, A.; Saglia, R.; Sharples, R. M.; Sternberg, A.; Tacchella, S.; van Dokkum, P.

    2014-11-01

    In this paper, we follow up on our previous detection of nuclear ionized outflows in the most massive (log(M */M ⊙) >= 10.9) z ~ 1-3 star-forming galaxies by increasing the sample size by a factor of six (to 44 galaxies above log(M */M ⊙) >= 10.9) from a combination of the SINS/zC-SINF, LUCI, GNIRS, and KMOS3Dspectroscopic surveys. We find a fairly sharp onset of the incidence of broad nuclear emission (FWHM in the Hα, [N II], and [S II] lines ~450-5300 km s-1), with large [N II]/Hα ratios, above log(M */M ⊙) ~ 10.9, with about two-thirds of the galaxies in this mass range exhibiting this component. Broad nuclear components near and above the Schechter mass are similarly prevalent above and below the main sequence of star-forming galaxies, and at z ~ 1 and ~2. The line ratios of the nuclear component are fit by excitation from active galactic nuclei (AGNs), or by a combination of shocks and photoionization. The incidence of the most massive galaxies with broad nuclear components is at least as large as that of AGNs identified by X-ray, optical, infrared, or radio indicators. The mass loading of the nuclear outflows is near unity. Our findings provide compelling evidence for powerful, high-duty cycle, AGN-driven outflows near the Schechter mass, and acting across the peak of cosmic galaxy formation. Based on observations obtained at the Very Large Telescope (VLT) of the European Southern Observatory (ESO), Paranal, Chile (ESO program IDs 073.B-9018, 074.A-9011, 075.A-0466, 076.A-0527, 078.A-0660, 079.A-0341, 080.A-0330, 080.A-0339, 080.A-0635, 081.A-0672, 082.A-0396, 183.A-0781, 087.A-0081, 088.A-0202, 088.A-0209, 091.A-0126, 092.A-0082, 092.A-0091, 093.A-0079). Also based on observations at the Large Binocular Telescope (LBT) on Mt. Graham in Arizona.

  18. A deep/wide 1-2 GHz snapshot survey of SDSS Stripe 82 using the Karl G. Jansky Very Large Array in a compact hybrid configuration

    NASA Astrophysics Data System (ADS)

    Heywood, I.; Jarvis, M. J.; Baker, A. J.; Bannister, K. W.; Carvalho, C. S.; Hardcastle, M.; Hilton, M.; Moodley, K.; Smirnov, O. M.; Smith, D. J. B.; White, S. V.; Wollack, E. J.

    2016-08-01

    We have used the Karl G. Jansky Very Large Array to image ˜100 deg2 of SDSS Stripe 82 at 1-2 GHz. The survey consists of 1026 snapshot observations of 2.5 min duration, using the hybrid CnB configuration. The survey has good sensitivity to diffuse, low surface brightness structures and extended radio emission, making it highly synergistic with existing 1.4 GHz radio observations of the region. The principal data products are continuum images, with 16 × 10 arcsec resolution, and a catalogue containing 11 782 point and Gaussian components resulting from fits to the thresholded Stokes-I brightness distribution, forming approximately 8948 unique radio sources. The typical effective 1σ noise level is 88 μJy beam-1. Spectral index estimates are included, as derived from the 1 GHz of instantaneous bandwidth. Astrometric and photometric accuracy are in excellent agreement with existing narrowband observations. A large-scale simulation is used to investigate clean bias, which we extend into the spectral domain. Clean bias remains an issue for snapshot surveys with the VLA, affecting our total intensity measurements at the ˜1σ level. Statistical spectral index measurements are in good agreement with existing measurements derived from matching separate surveys at two frequencies. At flux densities below ˜35σ the median in-band spectral index measurements begin to exhibit a bias towards flatness that is dependent on both flux density and the intrinsic spectral index. In-band spectral curvature measurements are likely to be unreliable for all but the very brightest components. Image products and catalogues are publicly available via an FTP server.

  19. In vitro induction of apoptosis vs. necrosis by widely used preservatives: 2-phenoxyethanol, a mixture of isothiazolinones, imidazolidinyl urea and 1,2-pentanediol.

    PubMed

    Anselmi, Cecilia; Ettorre, Anna; Andreassi, Marco; Centini, Marisanna; Neri, Paolo; Di Stefano, Anna

    2002-02-01

    Preservatives are added to many final products, such as detergents, cosmetics, pharmaceuticals and vaccines. We conducted an in vitro investigation of the apoptosis- and necrosis-inducing potential of brief applications (10 min) of four common preservatives: ethylene glycol monophenyl ether, 2-phenoxyethanol (EGPE), imidazolidinyl urea (IMU), a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one (CMI/MI), and 1,2-pentanediol, a "preservative-non-preservative" best known as pentylene glycol. Using HL60 cells, we monitored the kinetics of cell toxicity with the MTT test and analysed extranuclear end points of apoptosis, i.e. phosphatidylserine exposure and nuclear fragmentation. Preservative treatment resulted in a dose-dependent decrease of cell viability. The mode of cell death was dose-dependent: necrosis occurred at high concentrations while apoptosis, shown by DNA laddering, DNA sub-diploid peak and caspase-3 activation, occurred at lower concentrations 0-24hr after exposure to a single dose: CMI/MI induced apoptosis at low concentrations (0.001-0.01%) and necrosis at high concentrations (0.5-0.1%); IMU and EGPE required higher concentrations to induce apoptosis (IMU 0.01-0.1% and EGPE 0.01-0.5%) or necrosis (IMU 0.5-1% and EGPE only at 1%). PG induced apoptosis only at 5%. Externalization of PS, a hallmark of apoptosis, occurred early in HL60 treated with low concentrations of CMI/MI and EGPE and was concomitant with the subdiploid peak in HL60 treated with PG. However, it did not occur in HL60 treated with IMU. In conclusion, at appropriate concentrations, each of the four preservatives modulates the apoptotic machinery by a caspase-dependent mechanism. Thus, apoptosis could be a good parameter to evaluate the cytoxicity of these chemical compounds.

  20. A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion.

    PubMed

    Andritschke, Daniel; Dilling, Sabrina; Emmenlauer, Mario; Welz, Tobias; Schmich, Fabian; Misselwitz, Benjamin; Rämö, Pauli; Rottner, Klemens; Kerkhoff, Eugen; Wada, Teiji; Penninger, Josef M; Beerenwinkel, Niko; Horvath, Peter; Dehio, Christoph; Hardt, Wolf-Dietrich

    2016-01-01

    Salmonella Typhimurium (S. Tm) is a leading cause of diarrhea. The disease is triggered by pathogen invasion into the gut epithelium. Invasion is attributed to the SPI-1 type 3 secretion system (T1). T1 injects effector proteins into epithelial cells and thereby elicits rearrangements of the host cellular actin cytoskeleton and pathogen invasion. The T1 effector proteins SopE, SopB, SopE2 and SipA are contributing to this. However, the host cell factors contributing to invasion are still not completely understood. To address this question comprehensively, we used Hela tissue culture cells, a genome-wide siRNA library, a modified gentamicin protection assay and S. TmSipA, a sopBsopE2sopE mutant which strongly relies on the T1 effector protein SipA to invade host cells. We found that S. TmSipA invasion does not elicit membrane ruffles, nor promote the entry of non-invasive bacteria "in trans". However, SipA-mediated infection involved the SPIRE family of actin nucleators, besides well-established host cell factors (WRC, ARP2/3, RhoGTPases, COPI). Stage-specific follow-up assays and knockout fibroblasts indicated that SPIRE1 and SPIRE2 are involved in different steps of the S. Tm infection process. Whereas SPIRE1 interferes with bacterial binding, SPIRE2 influences intracellular replication of S. Tm. Hence, these two proteins might fulfill non-redundant functions in the pathogen-host interaction. The lack of co-localization hints to a short, direct interaction between S. Tm and SPIRE proteins or to an indirect effect. PMID:27627128

  1. Herschel observations of extraordinary sources: Analysis of the HIFI 1.2 THz wide spectral survey toward orion KL. I. method

    SciTech Connect

    Crockett, Nathan R.; Bergin, Edwin A.; Neill, Justin L.; Favre, Cécile; Schilke, Peter; Lis, Dariusz C.; Emprechtinger, Martin; Phillips, Thomas G.; Bell, Tom A.; Cernicharo, José; Esplugues, Gisela B.; Blake, Geoffrey; Kleshcheva, Maria; Gupta, Harshal; Pearson, John; Lord, Steven; Marcelino, Nuria; McGuire, Brett A.; Plume, Rene; Van der Tak, Floris; and others

    2014-06-01

    We present a comprehensive analysis of a broadband spectral line survey of the Orion Kleinmann-Low nebula (Orion KL), one of the most chemically rich regions in the Galaxy, using the HIFI instrument on board the Herschel Space Observatory. This survey spans a frequency range from 480 to 1907 GHz at a resolution of 1.1 MHz. These observations thus encompass the largest spectral coverage ever obtained toward this high-mass star-forming region in the submillimeter with high spectral resolution and include frequencies >1 THz, where the Earth's atmosphere prevents observations from the ground. In all, we detect emission from 39 molecules (79 isotopologues). Combining this data set with ground-based millimeter spectroscopy obtained with the IRAM 30 m telescope, we model the molecular emission from the millimeter to the far-IR using the XCLASS program, which assumes local thermodynamic equilibrium (LTE). Several molecules are also modeled with the MADEX non-LTE code. Because of the wide frequency coverage, our models are constrained by transitions over an unprecedented range in excitation energy. A reduced χ{sup 2} analysis indicates that models for most species reproduce the observed emission well. In particular, most complex organics are well fit by LTE implying gas densities are high (>10{sup 6} cm{sup –3}) and excitation temperatures and column densities are well constrained. Molecular abundances are computed using H{sub 2} column densities also derived from the HIFI survey. The distribution of rotation temperatures, T {sub rot}, for molecules detected toward the hot core is significantly wider than the compact ridge, plateau, and extended ridge T {sub rot} distributions, indicating the hot core has the most complex thermal structure.

  2. A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion

    PubMed Central

    Andritschke, Daniel; Dilling, Sabrina; Emmenlauer, Mario; Welz, Tobias; Schmich, Fabian; Misselwitz, Benjamin; Rämö, Pauli; Rottner, Klemens; Kerkhoff, Eugen; Wada, Teiji; Penninger, Josef M.; Beerenwinkel, Niko; Horvath, Peter; Dehio, Christoph; Hardt, Wolf-Dietrich

    2016-01-01

    Salmonella Typhimurium (S. Tm) is a leading cause of diarrhea. The disease is triggered by pathogen invasion into the gut epithelium. Invasion is attributed to the SPI-1 type 3 secretion system (T1). T1 injects effector proteins into epithelial cells and thereby elicits rearrangements of the host cellular actin cytoskeleton and pathogen invasion. The T1 effector proteins SopE, SopB, SopE2 and SipA are contributing to this. However, the host cell factors contributing to invasion are still not completely understood. To address this question comprehensively, we used Hela tissue culture cells, a genome-wide siRNA library, a modified gentamicin protection assay and S. TmSipA, a sopBsopE2sopE mutant which strongly relies on the T1 effector protein SipA to invade host cells. We found that S. TmSipA invasion does not elicit membrane ruffles, nor promote the entry of non-invasive bacteria "in trans". However, SipA-mediated infection involved the SPIRE family of actin nucleators, besides well-established host cell factors (WRC, ARP2/3, RhoGTPases, COPI). Stage-specific follow-up assays and knockout fibroblasts indicated that SPIRE1 and SPIRE2 are involved in different steps of the S. Tm infection process. Whereas SPIRE1 interferes with bacterial binding, SPIRE2 influences intracellular replication of S. Tm. Hence, these two proteins might fulfill non-redundant functions in the pathogen-host interaction. The lack of co-localization hints to a short, direct interaction between S. Tm and SPIRE proteins or to an indirect effect. PMID:27627128

  3. Herschel Observations of Extraordinary Sources: Analysis of the HIFI 1.2 THz Wide Spectral Survey toward Orion KL. I. Methods

    NASA Astrophysics Data System (ADS)

    Crockett, Nathan R.; Bergin, Edwin A.; Neill, Justin L.; Favre, Cécile; Schilke, Peter; Lis, Dariusz C.; Bell, Tom A.; Blake, Geoffrey; Cernicharo, José; Emprechtinger, Martin; Esplugues, Gisela B.; Gupta, Harshal; Kleshcheva, Maria; Lord, Steven; Marcelino, Nuria; McGuire, Brett A.; Pearson, John; Phillips, Thomas G.; Plume, Rene; van der Tak, Floris; Tercero, Belén; Yu, Shanshan

    2014-06-01

    We present a comprehensive analysis of a broadband spectral line survey of the Orion Kleinmann-Low nebula (Orion KL), one of the most chemically rich regions in the Galaxy, using the HIFI instrument on board the Herschel Space Observatory. This survey spans a frequency range from 480 to 1907 GHz at a resolution of 1.1 MHz. These observations thus encompass the largest spectral coverage ever obtained toward this high-mass star-forming region in the submillimeter with high spectral resolution and include frequencies >1 THz, where the Earth's atmosphere prevents observations from the ground. In all, we detect emission from 39 molecules (79 isotopologues). Combining this data set with ground-based millimeter spectroscopy obtained with the IRAM 30 m telescope, we model the molecular emission from the millimeter to the far-IR using the XCLASS program, which assumes local thermodynamic equilibrium (LTE). Several molecules are also modeled with the MADEX non-LTE code. Because of the wide frequency coverage, our models are constrained by transitions over an unprecedented range in excitation energy. A reduced χ2 analysis indicates that models for most species reproduce the observed emission well. In particular, most complex organics are well fit by LTE implying gas densities are high (>106 cm-3) and excitation temperatures and column densities are well constrained. Molecular abundances are computed using H2 column densities also derived from the HIFI survey. The distribution of rotation temperatures, T rot, for molecules detected toward the hot core is significantly wider than the compact ridge, plateau, and extended ridge T rot distributions, indicating the hot core has the most complex thermal structure. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.

  4. Temperature Structure of the 80 Km to 120 Km Region

    NASA Technical Reports Server (NTRS)

    Forbes, J. M.

    1985-01-01

    Between 80 and 120 km the CIRA 1972 model is based heavily on NASA Meteorological Sounding Rocket Program (MSRP) data collected prior to 1967. Since about 1970 an abundance of E-region (100-130 km) temperature data from the incoherent scatter facilities at Arecibo, Millstone Hill, and St. Santin have also become available. The present study examines the temperature structure of the 80 to 120 km region given considerable additional MSRP rocket data, thus providing better seasonal, latitudinal, and longitudinal coverage in the 80 to 100 km region, and a combination of incoherent scatter and rocket data in the 100 to 120 km region which allows a much improved delineation of lower thermosphere temperature structue. Although some individual station comparisons indicate measurable asymmetries in longitude and latitude, data are still insufficient to separate these effects. Specific recommendations of the new CIRA are given.

  5. KM Education in LIS Programs

    ERIC Educational Resources Information Center

    Rehman, Sajjad ur; Chaudhry, Abdus Sattar

    2005-01-01

    This paper investigates the perceptions of the heads of 12 Library and Information Science (LIS) schools on Knowledge Management (KM) education. These heads from North America, Europe and the Pacific region had either been offering KM courses or had an apparent interest in such programs. Data about perceptions were gathered on the nature of their…

  6. KM3NeT

    SciTech Connect

    Jong, M. de; Collaboration: KM3NeT Collaboration

    2015-07-15

    KM3NeT is a large research infrastructure, that will consist of a network of deep-sea neutrino telescopes in the Mediterranean Sea. The main objective of KM3NeT is the discovery and subsequent observation of high-energy neutrino sources in the Universe. A further physics perspective is the measurement of the mass hierarchy of neutrinos. A corresponding study, ORCA, is ongoing within KM3NeT. A cost effective technology for (very) large water Cherenkov detectors has been developed based on a new generation of low price 3-inch photo-multiplier tubes. Following the successful deployment and operation of two prototypes, the construction of the KM3NeT research infrastructure has started. The prospects of the different phases of the implementation of KM3NeT are summarised.

  7. KM3NeT

    NASA Astrophysics Data System (ADS)

    de Jong, M.

    2015-07-01

    KM3NeT is a large research infrastructure, that will consist of a network of deep-sea neutrino telescopes in the Mediterranean Sea. The main objective of KM3NeT is the discovery and subsequent observation of high-energy neutrino sources in the Universe. A further physics perspective is the measurement of the mass hierarchy of neutrinos. A corresponding study, ORCA, is ongoing within KM3NeT. A cost effective technology for (very) large water Cherenkov detectors has been developed based on a new generation of low price 3-inch photo-multiplier tubes. Following the successful deployment and operation of two prototypes, the construction of the KM3NeT research infrastructure has started. The prospects of the different phases of the implementation of KM3NeT are summarised.

  8. Origins of the 520-km discontinuity

    NASA Astrophysics Data System (ADS)

    Vinnik, Lev

    2016-04-01

    The 520-km discontinuity is often explained by the phase transition from wadsleyite to ringwoodite, although the theoretical impedance of this transition is so small that the related converted and reflected seismic phases could hardly be seen in the seismograms. At the same time there are numerous reports on observations of a large discontinuity at this depth, especially in the data on SS precursors and P-wave wide-angle reflections. Revenaugh and Jordan (1991) argued that this discontinuity is related to the garnet/post-garnet transformation. Gu et al. (1998) preferred very deep continental roots extending into the transition zone. Deuss and Woodhouse proposed splitting of the 520-km discontinuity into two discontinuities, whilst Bock (1994) denied evidence of the 520-km discontinuity in the SS precursors. Our approach to this problem is based on the analysis of S and P receiver functions. Most of our data are related to hot-spots in and around the Atlantic where the appropriate converted phases are often comparable in amplitude with P410s and S410p. Both S and P receiver functions provide strong evidence of a low S velocity in a depth range from 450 km to 510 km at some locations. The 520-km discontinuity appears to be the base of this low-velocity layer. Our observations of the low S velocity in the upper transition zone are very consistent with the indications of a drop in the solidus temperature of carbonated peridotite in the same pressure range (Keshav et al. 2011), and this phenomenon provides a viable alternative to the other explanations of the 520-km discontinuity.

  9. Laboratory 20-km cycle time trial reproducibility.

    PubMed

    Zavorsky, G S; Murias, J M; Gow, J; Kim, D J; Poulin-Harnois, C; Kubow, S; Lands, L C

    2007-09-01

    This study evaluated the reproducibility of laboratory based 20-km time trials in well trained versus recreational cyclists. Eighteen cyclists (age = 34 +/- 8 yrs; body mass index = 23.1 +/- 2.2 kg/m (2); VO(2max) = 4.19 +/- 0.65 L/min) completed three 20-km time trials over a month on a Velotron cycle ergometer. Average power output (PO) (W), speed, and heart rate (HR) were significantly lower in the first time trial compared to the second and third time trial. The coefficients of variation (CV) between the second and third trial of the top eight performers for average PO, time to completion, and speed were 1.2 %, 0.6 %, 0.5 %, respectively, compared to 4.8 %, 2.0 %, and 2.3 % for the bottom ten. In addition, the average HR, VO(2), and percentage of VO(2max) were similar between trials. This study demonstrated that (1) a familiarization session improves the reliability of the measurements (i.e., average PO, time to completion and speed), and (2) the CV was much smaller for the best performers.

  10. Amplification and generation of radiation at the 4{sup 2{Gamma}} {yields} 1,2{sup 2{Gamma}} transition of the Kr{sub 2}F molecule in an electron-beam-pumped wide-aperture laser

    SciTech Connect

    Levchenko, A O; Zvorykin, V D; Likhomanova, S V; Ustinovskii, N N; Shtan'ko, V F

    2010-05-26

    The radiation amplification and oscillation are obtained in an electron-beam-pumped Berdysh laser with an active volume of 10 L in the visible range from 430 to 470 nm at the broadband 4{sup 2{Gamma}} {yields} 1,2{sup 2{Gamma}} transition in the triatomic Kr{sub 2}F molecule of interest for amplification of ultrashort laser pulses. It is shown that, along with absorption of laser radiation in the active medium, the amplification dynamics is considerably determined by short-lived absorption induced in the amplifier windows by bremsstrahlung X-rays. For the specific pump power 0.6 - 0.7 MW cm{sup -3}, the gain, corrected for nonstationary absorption, was {approx}10{sup -3} cm{sup -1}. A scheme of a Kr{sub 2}F amplifier is proposed for amplification of ultrashort pulses up to multiterawatt peak powers in the active volume {approx}10 L. (lasers)

  11. The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism.

    PubMed

    Yu, Woo Sik; Jeong, Soo-Jin; Kim, Ji-Hyun; Lee, Hyo-Jung; Song, Hyo Sook; Kim, Min-Seok; Ko, Eunjung; Lee, Hyo-Jeong; Khil, Jae-Ho; Jang, Hyeung-Jin; Kim, Young Chul; Bae, Hyunsu; Chen, Chang Yan; Kim, Sung-Hoon

    2011-08-01

    1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a polyphenolic compound isolated from Rhus chinensis Mill. PGG has been known to have anti-tumor, anti-angiogenic and anti-diabetic activities. The present study revealed another underlying molecular target of PGG in MDA-MB-231 breast cancer cells by using Illumina Human Ref-8 expression BeadChip assay. Through the Beadstudio v3 micro assay program to compare the identified genes expressed in PGG-treated MDA-MB-231 cells with untreated control, we found several unique genes that are closely associated with pyruvate metabolism, glycolysis/gluconeogenesis and tyrosine metabolism, including PC, ACSS2, ACACA, ACYP2, ALDH3B1, FBP1, PRMT2 and COMT. Consistent with microarray data, real-time RT-PCR confirmed the significant down-regulation of these genes at mRNA level in PGG-treated MDA-MB-231 cells. Our findings suggest the potential of PGG as anticancer agent for breast cancer cells by targeting cancer metabolism genes.

  12. The Genome-Wide Expression Profile of 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose-Treated MDA-MB-231 Breast Cancer Cells: Molecular Target on Cancer Metabolism

    PubMed Central

    Yu, Woo Sik; Jeong, Soo-Jin; Kim, Ji-Hyun; Lee, Hyo-Jung; Song, Hyo Sook; Kim, Min-Seok; Ko, Eunjung; Lee, Hyo-Jeong; Khil, Jae-Ho; Jang, Hyeung-Jin; Kim, Young Chul; Bae, Hyunsu; Chen, Chang Yan; Kim, Sung-Hoon

    2011-01-01

    1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a polyphenolic compound isolated from Rhus chinensis Mill. PGG has been known to have anti-tumor, anti-angiogenic and anti-diabetic activities. The present study revealed another underlying molecular target of PGG in MDA-MB-231 breast cancer cells by using Illumina Human Ref-8 expression BeadChip assay. Through the Beadstudio v3 micro assay program to compare the identified genes expressed in PGG-treated MDA-MB-231 cells with untreated control, we found several unique genes that are closely associated with pyruvate metabolism, glycolysis/gluconeogenesis and tyrosine metabolism, including PC, ACSS2, ACACA, ACYP2, ALDH3B1, FBP1, PRMT2 and COMT. Consistent with microarray data, real-time RT-PCR confirmed the significant down-regulation of these genes at mRNA level in PGG-treated MDA-MB-231 cells. Our findings suggest the potential of PGG as anticancer agent for breast cancer cells by targeting cancer metabolism genes. PMID:21614488

  13. 1,2-Dichloroethane

    Integrated Risk Information System (IRIS)

    1,2 - Dichloroethane ; CASRN 107 - 06 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge

  14. 1,2-Dichloropropane

    Integrated Risk Information System (IRIS)

    1,2 - Dichloropropane ; CASRN 78 - 87 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge

  15. 1,2-Dichlorobenzene

    Integrated Risk Information System (IRIS)

    1,2 - Dichlorobenzene ; CASRN 95 - 50 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge

  16. 1,2-Diphenylhydrazine

    Integrated Risk Information System (IRIS)

    1,2 - Diphenylhydrazine ; CASRN 122 - 66 - 7 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcin

  17. 1,2-Dibromoethane

    Integrated Risk Information System (IRIS)

    1,2 - Dibromoethane ; CASRN 106 - 93 - 4 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogen

  18. 4-km body(ies?) embedded in Saturn's Huygens Ringlet

    NASA Astrophysics Data System (ADS)

    Spitale, Joseph N.; Hahn, Joseph M.; Tamayo, Daniel

    2016-05-01

    Saturn's 20-km-wide Huygens ringlet, located ~250 km exterior to the B ring, displays unusual kinematics, as evidenced by a time variable width-relation. The cause of this behavior is not clear, but may be related to the presence of large embedded bodies (Spitale and Hahn 2016). The largest such bodies produce half-propeller-shaped disturbances originating at the inner edge of the ringlet, whose radial widths imply a size of ~4 km, based on simple scaling from A-ring propellers. Here, we show that a numerical N-body model of the ringlet with a 4-km body embedded near the inner edge produces features that are consistent with the observed half propellers.

  19. Neutrophil haptotaxis induced by the lectin KM+.

    PubMed

    Ganiko, L; Martins, A R; Espreáfico, E M; Roque-Barreira, M C

    1998-05-01

    KM+ is a D-mannose binding lectin from Artocarpus integrifolia that induces neutrophil migration in vitro and in vivo. This attractant activity was shown to be caused by haptotaxis rather than chemotaxis. The inhibition by D-mannose of the neutrophil attraction exerted by KM+, both in vitro and in vivo, supports the idea that haptotaxis is triggered in vivo by the sugar binding sites interacting with glycoconjugates located on the neutrophil surface and in the extracellular matrix. In the present study an in vivo haptotaxis assay was performed by intradermally (i.d.) injecting 125I-KM+ (200 ng), which led to a selective staining of loose connective tissue and vascular endothelium. The radiolabelled area exhibited a maximum increase (five-fold) in neutrophil infiltration 3 h after injection, relative to i.d. 200 ng 125I-BSA. We characterized the ex vivo binding of KM+ to tissue elements by immunohistochemistry, using paraformaldehyde-fixed, paraffin-embedded, untreated rat skin. Bound KM+ was detected with an affinity-purified rabbit IgG anti-KM+ and visualized with an alkaline phosphatase based system. KM+ binding to connective tissue and vascular endothelium was inhibited by preincubating KM+ with 0.4 mM D-mannose and was potentiated by heparan sulfate (100 microg ml(-1)). An in vitro assay carried out in a Boyden microchamber showed that heparan sulfate potentiated the attractant effect of 10 microg KM+ by 34%. The present data suggest that KM+ induces neutrophil migration in vivo by haptotaxis and that the haptotactic gradient could be provided by the interaction of the KM+ carbohydrate recognition site(s) with mannose-containing glycoconjugate(s) in vascular endothelium and connective tissue. Heparan sulfate would act as an accessory molecule, enhancing the KM+ tissue binding and potentiating the induced neutrophil haptotaxis.

  20. Analysis of sex differences in open-water ultra-distance swimming performances in the FINA World Cup races in 5 km, 10 km and 25 km from 2000 to 2012

    PubMed Central

    2014-01-01

    Background The present study investigated the changes in swimming speeds and sex differences for elite male and female swimmers competing in 5 km, 10 km and 25 km open-water FINA World Cup races held between 2000 and 2012. Methods The changes in swimming speeds and sex differences across years were analysed using linear, non-linear, and multi-level regression analyses for the annual fastest and the annual ten fastest competitors. Results For the annual fastest, swimming speed remained stable for men and women in 5 km (5.50 ± 0.21 and 5.08 ± 0.19 km/h, respectively), in 10 km (5.38 ± 0.21 and 5.05 ± 0.26 km/h, respectively) and in 25 km (5.03 ± 0.32 and 4.58 ± 0.27 km/h, respectively). In the annual ten fastest, swimming speed remained constant in 5 km in women (5.02 ± 0.19 km/h) but decreased significantly and linearly in men from 5.42 ± 0.03 km/h to 5.39 ± 0.02 km/h. In 10 km, swimming speed increased significantly and linearly in women from 4.75 ± 0.01 km/h to 5.74 ± 0.01 km/h but remained stable in men at 5.36 ± 0.21 km/h. In 25 km, swimming speed decreased significantly and linearly in women from 4.60 ± 0.06 km/h to 4.44 ± 0.08 km/h but remained unchanged at 4.93 ± 0.34 km/h in men. For the annual fastest, the sex difference in swimming speed remained unchanged in 5 km (7.6 ± 3.0%), 10 km (6.1 ± 2.5%) and 25 km (9.0 ± 3.7%). For the annual ten fastest, the sex difference remained stable in 5 km at 7.6 ± 0.6%, decreased significantly and linearly in 10 km from 7.7 ± 0.7% to 1.2 ± 0.3% and increased significantly and linearly from 4.7 ± 1.4% to 9.6 ± 1.5% in 25 km. Conclusions To summarize, elite female open-water ultra-distance swimmers improved in 10 km but impaired in 25 km leading to a linear decrease in sex difference in 10 km and a linear increase in sex difference in 25 km. The linear changes in sex differences

  1. Hyperfine-resolved 3.4-{mu}m spectroscopy of CH{sub 3}I with a widely tunable difference frequency generation source and a cavity-enhanced cell: A case study of a local Coriolis interaction between the v{sub 1}=1 and (v{sub 2},v{sub 6}{sup l})=(1,2{sup 2}) states

    SciTech Connect

    Okubo, Sho; Nakayama, Hirotaka; Sasada, Hiroyuki

    2011-01-15

    Saturated absorption spectra of the {nu}{sub 1} fundamental band of CH{sub 3}I are recorded with a cavity-enhanced cell and a tunable difference frequency generation source having an 86-cm{sup -1} range. The recorded spectral lines are 250 kHz wide, and most of them are resolved into the individual hyperfine components. The Coriolis interaction between the v{sub 1}=1 and (v{sub 2},v{sub 6}{sup l})=(1,2{sup 2}) states locally perturbing the hyperfine structures is analyzed to yield the Coriolis and hyperfine coupling constants with uncertainties similar to those in typical microwave spectroscopy. The spectrometer has demonstrated the potential for precisely determining the energy structure in the vibrational excited states.

  2. News from KM3NeT

    SciTech Connect

    Katz, Ulrich F.; Collaboration: KM3NeT Collaboration

    2014-11-18

    KM3NeT is a future research infrastructure in the Mediterranean Sea, hosting a multi-cubic-kilometre neutrino telescope and nodes for Earth and Sea sciences. In this report we shortly summarise the genesis of the KM3NeT project and present key elements of its technical design. The physics objectives of the KM3NeT neutrino telescope and some selected sensitivity estimates are discussed. Finally, some first results from prototype operations and the next steps towards implementation – in particular the first construction phase in 2014/15 – are described.

  3. Status of KM3NeT

    NASA Astrophysics Data System (ADS)

    Riccobene, G.

    2016-07-01

    The recent observation of cosmic neutrinos by IceCube has pushed the quest towards the identification of cosmic sources of high-energy particles. The KM3NeT Collaboration is now ready to launch the massive construction of detection units to be installed in deep sea to build a km-cubic size neutrino telescope. The main elements of the detector, the status of the project and the expected perfomances are briefly reported.

  4. Towards Mapping the Ocean Surface Topography at 1 km Resolution

    NASA Technical Reports Server (NTRS)

    Fu, Lee-Lueng; Rodriquez, Ernesto

    2006-01-01

    We propose to apply the technique of synthetic aperture radar interferometry to the measurement of ocean surface topography at spatial resolution approaching 1 km. The measurement will have wide ranging applications in oceanography, hydrology, and marine geophysics. The oceanographic and related societal applications are briefly discussed in the paper. To meet the requirements for oceanographic applications, the instrument must be flown in an orbit with proper sampling of ocean tides.

  5. AC conductivity and relaxation mechanism in (Nd1/2Li1/2)(Fe1/2V1/2)O3 ceramics

    NASA Astrophysics Data System (ADS)

    Nath, Susmita; Barik, Subrat Kumar; Choudhary, R. N. P.

    2016-05-01

    In the present study we have synthesized polycrystalline sample of (Nd1/2Li1/2)(Fe1/2V1/2)O3 ceramic by a standard high-temperature solid-state reaction technique. Studies of dielectric and electrical properties of the compound have been carried out in a wide range of temperature (RT - 400 °C) and frequency (1kHz - 1MHz) using complex impedance spectroscopic technique. The imaginary vs. real component of the complex impedance plot (Nyquist plot) of the prepared sample exhibits the existence of grain, grain boundary contributions in the complex electrical parameters and negative temperature coefficient of resistance (NTCR) type behavior like semiconductor. Details study of ac conductivity plot reveals that the material obeys universal Jonscher's power law.

  6. KM3NeT-ARCA project status and plan

    NASA Astrophysics Data System (ADS)

    Coniglione, R.

    2016-04-01

    The KM3NeT Collaboration aims at building a research infrastructure in the depths of the Mediterranean Sea hosting a cubic kilometre neutrino telescope. The KM3NeT/ARCA detector is the ideal instrument to look for high-energy neutrino sources thanks to the latitude of the detector and to the optical characteristics of the sea water. The detector latitude allows for a wide coverage of the observable sky including the region of the Galactic centre and the optical sea water properties allow for the measure of the neutrino direction with excellent angular resolution also for cascade events. The technologically innovative components of the detector and the status of construction will be presented as well as the capability it offers to discover neutrinos.

  7. The estimation of 550 km x 550 km mean gravity anomalies. [from free atmosphere gravimetry data

    NASA Technical Reports Server (NTRS)

    Williamson, M. R.; Gaposchkin, E. M.

    1975-01-01

    The calculation of 550 km X 550 km mean gravity anomalies from 1 degree X 1 degree mean free-air gravimetry data is discussed. The block estimate procedure developed by Kaula was used, and estimates for 1452 of the 1654 blocks were obtained.

  8. Large Circular Basin - 1300-km diameter

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Close-up view of one-half of a 1300-km diameter circular basin the largest observed on Mercury. The other half is hidden beyond the terminator to the left. Hills and valleys extend in a radial fashion outward from the main ring. Interior of the large basin is completely flooded by plains materials; adjacent lowlands are also partially flooded and superimposed on the plains are bowl shaped craters. Wrinkle ridges are abundant on the plains materials. The area shown is 1008 miles (1600 km) from the top to the bottom of the picture. Sun's illumination is from the right. Blurred linear lines extending across the picture near bottom are missing data lines that have been filled in by the computer. Mariner 10 encountered Mercury on Friday, March 29th, 1974, passing the planet on the darkside 431 miles (690-km) from the surface.

    The Mariner 10 mission, managed by the Jet Propulsion Laboratory for NASA's Office of Space Science, explored Venus in February 1974 on the way to three encounters with Mercury-in March and September 1974 and in March 1975. The spacecraft took more than 7,000 photos of Mercury, Venus, the Earth and the Moon.

    NOTE: This image was scanned from physical media.

  9. Km3Net Italy - Seafloor network

    NASA Astrophysics Data System (ADS)

    Papaleo, Riccardo

    2016-04-01

    The KM3NeT European project aims to construct a large volume underwater neutrino telescope in the depths of the Mediterranean Sea. INFN and KM3NeT collaboration, thanks to a dedicated funding of 21.000.000 € (PON 2007-2013), are committed to build and deploy the Phase 1 of the telescope, composed of a network of detection units: 8 towers, equipped with single photomultiplier optical modules, and 24 strings, equipped with multi-photomultipliers optical modules. All the towers and strings are connected to the main electro optical cable by means of a network of junction boxes and electro optical interlink cables. Each junction box is an active node able to provide all the necessary power to the detection units and to guarantee the data transmission between the detector and the on-shore control station. The KM3NeT Italia project foresees the realization and the installation of the first part of the deep sea network, composed of three junction boxes, one for the towers and two for the strings. In July 2015, two junction boxes have been deployed and connected to the new cable termination frame installed during the same sea campaign. The third and last one will be installed in November 2015. The status of the deep sea network is presented together with technical details of the project.

  10. Towards a 1km resolution global flood risk model

    NASA Astrophysics Data System (ADS)

    Bates, Paul; Neal, Jeff; Sampson, Chris; Smith, Andy

    2014-05-01

    Recent advances in computationally efficient numerical algorithms and new High Performance Computing architectures now make high (1-2km) resolution global hydrodynamic models a realistic proposition. However in many areas of the world the data sets and tools necessary to undertake such modelling do not currently exist. In particular, five major problems need to be resolved: (1) the best globally available terrain data (SRTM) was generated from X-band interferometric radar data which does not penetrate vegetation canopies and which has significant problems in determining ground elevations in urban areas; (2) a global river bathymetry data set does not currently exist; (3) most river channels globally are less than the smallest currently resolvable grid scale (1km) and therefore require a sub-grid treatment; (4) a means to estimate the magnitude of the T year flood at any point along the global river network does not currently exist; and (5) a large proportion of flood losses are generated by off-floodplain surface water flows which are not well represented in current hydrodynamic modelling systems. In this paper we propose solutions to each of these five issues as part of a concerted effort to develop a 1km (or better) resolution global flood hazard model. We describe the new numerical algorithms, computer architectures and computational resources used, and demonstrate solutions to the five previously intractable problems identified above. We conduct a validation study of the modelling against satellite imagery of major flooding on the Mississippi-Missouri confluence plain in the central USA before outlining a proof-of-concept regional study for SE Asia as a step towards a global scale model. For SE Asia we simulate flood hazard for ten different flood return periods over the entire Thailand, Cambodia, Vietnam, Malaysia and Laos region at 1km resolution and show that the modelling produces coherent, consistent and sensible simulations of extent and water depth.

  11. Saqqar: A 34 km diameter impact structure in Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Kenkmann, Thomas; Afifi, Abdulkader M.; Stewart, Simon A.; Poelchau, Michael H.; Cook, Douglas J.; Neville, Allen S.

    2015-11-01

    Here we present the first proof of an impact origin for the Saqqar circular structure in northwestern Saudi Arabia (Neville et al. ), with an apparent diameter of 34 km, centered at 29°35'N, 38°42'E. The structure is formed in Cambrian-Devonian siliciclastics and is unconformably overlain by undeformed Cretaceous and Paleogene sediments. The age of impact is not well constrained and lies somewhere between 410 and 70 Ma. The subsurface structure is constrained by 2-D reflection seismic profiles and six drilled wells. First-order structural features are a central uplift that rises approximately 2 km above regional datums, surrounded by a ring syncline. The crater rim is defined by circumferential normal faults. The central uplift and ring syncline correspond to a Bouguer gravity high and an annular ring-like low, respectively. The wells were drilled within the central uplift, the deepest among them exceed 2 km depth. Sandstone core samples from these wells show abundant indicators of a shock metamorphic overprint. Planar deformation features (PDFs) were measured with orientations along (0001), {101¯3}, and less frequently along {101¯1} and {101¯4}. Planar fractures (PFs) predominantly occur along (0001) and {101¯1}, and are locally associated with feather features (FFs). In addition, some shocked feldspar grains and strongly deformed mica flakes were found. The recorded shock pressure ranges between 5 and 15 GPa. The preserved level of shock and the absence of an allochthonous crater fill suggest that Saqqar was eroded by 1-2 km between the Devonian and Maastrichtian. The documentation of unequivocal shock features proves the formation of the Saqqar structure by a hypervelocity impact event.

  12. Global modeling with GEOS-5 from 50-km to 1-km with a single unified GCM

    NASA Astrophysics Data System (ADS)

    Putman, William; Suarez, Max; Molod, Andrea; Barahona, Donifan

    2015-04-01

    The Goddard Earth Observing System model (GEOS-5) of the Global Modeling and Assimilation Office (GMAO) at NASA Goddard Space Flight Center is uniquely designed to adapt to increasing resolution. This supports application of GEOS-5 for decadal scale climate simulation and reanalysis with a horizontal resolution of 50-kilometers (km), high-resolution numerical weather prediction at 25- to 14-km, and global mesoscale modeling at resolutions of 7- to 1.5-km. Resolution-aware parameterizations and dynamics support this diverse portfolio of applications within a single unified GEOS-5 GCM code-base. We will discuss the adaptation of physics parameterizations with increasing resolution. This includes the role of deep convective parameterization, the move to an improved two-moment microphysics scheme, the need for shallow convective parameterization, and the role of non-hydrostatic dynamics and implicit/explicit damping. Parameterization and dynamics evaluation are explored not only in global integrations with GEOS-5 but with radiative convective equilibrium tests that permit the rapid exploration of high-resolution simulations in a smaller doubly periodic Cartesian domain. Simulation results will highlight intercomparisons of model biases in cloud forcing and precipitation from the 30-year 50-km MERRA-2 reanalysis, 50- to 25-km free-running AMIP simulations, a 2-year 7-km global mesoscale simulation, and monthly global simulations at 3.5-km. A global 1.5-km simulation with GEOS-5 highlights our pursuit of truly convection permitting global simulations with GEOS-5. The tuning evaluation for this simulation using doubly periodic radiative convective equilibrium experiments will be discussed.

  13. Improved Blocking at 25km Resolution?

    NASA Astrophysics Data System (ADS)

    Schiemann, R.; Demory, M. E.; Mizielinski, M.; Roberts, M.; Shaffrey, L.; Strachan, J.; Vidale, P. L.; Matsueda, M.

    2014-12-01

    It has been suggested that relatively coarse resolution of atmospheric general circulation models (AGCMs) limits their ability to represent mid-latitude blocking. Assessing the role of model resolution for blocking is computationally expensive, as multi-decadal simulations at the desired resolution are necessary for a robust estimation of blocking statistics. Here, we use an ensemble of three atmosphere-only global models for which simulations that fulfil this requirement are available at resolutions of roughly 25km horizontal grid spacing in the mid-latitudes. This corresponds to about a fourfold increase in resolution over the highest-resolution CMIP5 (Coupled Model Intercomparison Project, Phase 5) models. The three models are (i) the ECMWF model (IFS) as used in the project Athena, (ii) the MRI-AGCM 3.2, and (iii) our own HadGEM3-GA3 simulations obtained in the UPSCALE project (UK on PrACE - weather-resolving Simulations of Climate for globAL Environmental risk). We use a two-dimensional blocking index to assess the representation of blocking in these simulations and in three reanalyses (ERA-Interim, ERA-40, MERRA). We evaluate the spatial distribution of climatological blocking frequency, the interannual variability of blocking occurrence as well as the persistence of blocking events. Furthermore, the degree to which blocking biases are associated with mean-state biases is quantified in the different models. We find that the representation of blocking remains very sensitive to atmospheric resolution as the grid spacing is reduced to about 25km. The simulated blocking frequency increases with resolution, mostly so as to reduce the model bias, yet there is considerable variation between the results obtained for different models, seasons, and for the Atlantic and Pacific regions.

  14. trans-1,2-Dichloroethylene

    Integrated Risk Information System (IRIS)

    trans - 1,2 - Dichloroethylene ; CASRN 156 - 60 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for No

  15. 1,2,4-Tribromobenzene

    Integrated Risk Information System (IRIS)

    1,2,4 - Tribromobenzene ; CASRN 615 - 54 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcin

  16. 1,1,2-Trichloropropane

    Integrated Risk Information System (IRIS)

    1,1,2 - Trichloropropane ; CASRN 598 - 77 - 6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarci

  17. 1,2,3-Trichloropropane

    Integrated Risk Information System (IRIS)

    1,2,3 - Trichloropropane ; CASRN 96 - 18 - 4 Human health assessment information on a chemical substance is included in IRIS only after a comprehensive review of toxicity data by U.S . EPA health scientists from several program offices , regional offices , and the Office of Research and Development

  18. cis-1,2-Dichloroethylene

    Integrated Risk Information System (IRIS)

    cis - 1,2 - Dichloroethylene ; CASRN 156 - 59 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Nonc

  19. 1,1,2-Trichloroethane

    Integrated Risk Information System (IRIS)

    1,1,2 - Trichloroethane ; CASRN 79 - 00 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcino

  20. 1,2,4-Trichlorobenzene

    Integrated Risk Information System (IRIS)

    1,2,4 - Trichlorobenzene ; CASRN 120 - 82 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarci

  1. 1,2-Epoxybutane (EBU)

    Integrated Risk Information System (IRIS)

    1,2 - Epoxybutane ( EBU ) ; CASRN 106 - 88 - 7 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarc

  2. 45 Km Horizontal Path Optical Link Experiment

    NASA Technical Reports Server (NTRS)

    Biswas, A.; Ceniceros, J.; Novak, M.; Jeganathan, M.; Portillo, A.; Erickson, D.; Depew, J.; Sanii, B.; Lesh, J. R.

    2000-01-01

    Mountain-top to mountain-top optical link experiments have been initiated at JPL, in order to perform a systems level evaluation of optical communications. Progress made so far is reported. ne NASA, JPL developed optical communications demonstrator (OCD) is used to transmit a laser signal from Strawberry Peak (SP), located in the San Bernadino mountains of California. This laser beam is received by a 0.6 m aperture telescope at JPL's Table Mountain Facility (TMF), located in Wrightwood, California. The optical link is bi-directional with the TMF telescope transmitting a continuous 4-wave (cw) 780 run beacon and the OCD sending back a 840 nm, 100 - 500 Mbps pseudo noise (PN) modulated, laser beam. The optical link path is at an average altitude of 2 km above sea level, covers a range of 46.8 km and provides an atmospheric channel equivalent to approx. 4 air masses. Average received power measured at either end fall well within the uncertainties predicted by link analysis. The reduction in normalized intensity variance (sigma(sup 2, sub I)) for the 4-beam beacon, compared to each individual beam, at SP, was from approx. 0.68 to 0.22. With some allowance for intra-beam mis-alignment, this is consistent with incoherent averaging. The sigma(sup2, sub I) measured at TMF approx. 0.43 +/- 0.22 exceeded the expected aperture averaged value of less than 0.1, probably because of beam wander. The focused spot sizes of approx. 162 +/- 6 microns at the TMF Coude and approx. 64 +/- 3 microns on the OCD compare to the predicted size range of 52 - 172 microns and 57 - 93 microns, respectively. This is consistent with 4 - 5 arcsec of atmospheric "seeing". The preliminary evaluation of OCD's fine tracking indicates that the uncompensated tracking error is approx. 3.3 micro rad compared to approx. 1.7 micro rad observed in the laboratory. Fine tracking performance was intermittent, primarily due to beacon fades on the OCD tracking sensor. The best bit error rates observed while

  3. Teleportation of entanglement over 143 km.

    PubMed

    Herbst, Thomas; Scheidl, Thomas; Fink, Matthias; Handsteiner, Johannes; Wittmann, Bernhard; Ursin, Rupert; Zeilinger, Anton

    2015-11-17

    As a direct consequence of the no-cloning theorem, the deterministic amplification as in classical communication is impossible for unknown quantum states. This calls for more advanced techniques in a future global quantum network, e.g., for cloud quantum computing. A unique solution is the teleportation of an entangled state, i.e., entanglement swapping, representing the central resource to relay entanglement between distant nodes. Together with entanglement purification and a quantum memory it constitutes a so-called quantum repeater. Since the aforementioned building blocks have been individually demonstrated in laboratory setups only, the applicability of the required technology in real-world scenarios remained to be proven. Here we present a free-space entanglement-swapping experiment between the Canary Islands of La Palma and Tenerife, verifying the presence of quantum entanglement between two previously independent photons separated by 143 km. We obtained an expectation value for the entanglement-witness operator, more than 6 SDs beyond the classical limit. By consecutive generation of the two required photon pairs and space-like separation of the relevant measurement events, we also showed the feasibility of the swapping protocol in a long-distance scenario, where the independence of the nodes is highly demanded. Because our results already allow for efficient implementation of entanglement purification, we anticipate our research to lay the ground for a fully fledged quantum repeater over a realistic high-loss and even turbulent quantum channel.

  4. Teleportation of entanglement over 143 km

    PubMed Central

    Herbst, Thomas; Scheidl, Thomas; Fink, Matthias; Handsteiner, Johannes; Wittmann, Bernhard; Ursin, Rupert; Zeilinger, Anton

    2015-01-01

    As a direct consequence of the no-cloning theorem, the deterministic amplification as in classical communication is impossible for unknown quantum states. This calls for more advanced techniques in a future global quantum network, e.g., for cloud quantum computing. A unique solution is the teleportation of an entangled state, i.e., entanglement swapping, representing the central resource to relay entanglement between distant nodes. Together with entanglement purification and a quantum memory it constitutes a so-called quantum repeater. Since the aforementioned building blocks have been individually demonstrated in laboratory setups only, the applicability of the required technology in real-world scenarios remained to be proven. Here we present a free-space entanglement-swapping experiment between the Canary Islands of La Palma and Tenerife, verifying the presence of quantum entanglement between two previously independent photons separated by 143 km. We obtained an expectation value for the entanglement-witness operator, more than 6 SDs beyond the classical limit. By consecutive generation of the two required photon pairs and space-like separation of the relevant measurement events, we also showed the feasibility of the swapping protocol in a long-distance scenario, where the independence of the nodes is highly demanded. Because our results already allow for efficient implementation of entanglement purification, we anticipate our research to lay the ground for a fully fledged quantum repeater over a realistic high-loss and even turbulent quantum channel. PMID:26578764

  5. Teleportation of entanglement over 143 km.

    PubMed

    Herbst, Thomas; Scheidl, Thomas; Fink, Matthias; Handsteiner, Johannes; Wittmann, Bernhard; Ursin, Rupert; Zeilinger, Anton

    2015-11-17

    As a direct consequence of the no-cloning theorem, the deterministic amplification as in classical communication is impossible for unknown quantum states. This calls for more advanced techniques in a future global quantum network, e.g., for cloud quantum computing. A unique solution is the teleportation of an entangled state, i.e., entanglement swapping, representing the central resource to relay entanglement between distant nodes. Together with entanglement purification and a quantum memory it constitutes a so-called quantum repeater. Since the aforementioned building blocks have been individually demonstrated in laboratory setups only, the applicability of the required technology in real-world scenarios remained to be proven. Here we present a free-space entanglement-swapping experiment between the Canary Islands of La Palma and Tenerife, verifying the presence of quantum entanglement between two previously independent photons separated by 143 km. We obtained an expectation value for the entanglement-witness operator, more than 6 SDs beyond the classical limit. By consecutive generation of the two required photon pairs and space-like separation of the relevant measurement events, we also showed the feasibility of the swapping protocol in a long-distance scenario, where the independence of the nodes is highly demanded. Because our results already allow for efficient implementation of entanglement purification, we anticipate our research to lay the ground for a fully fledged quantum repeater over a realistic high-loss and even turbulent quantum channel. PMID:26578764

  6. Variation of electron and ion density distribution along Earth's magnetic field line deduced from whistler mode (wm) sounding of image/rpi satellite below altitude 5000 km

    NASA Astrophysics Data System (ADS)

    Hazra, Susmita

    This thesis provides a detailed survey and analysis of whistler mode (WM) echoes observed by IMAGE/RPI satellite during the years 2000-2005 below the altitude of 5000 km. Approximately 2500 WM echoes have been observed by IMAGE during this period. This includes mostly specularly reflected whistler mode (SRWM) echoes and ~400 magnetospherically reflected whistler mode (MRWM) echoes. Stanford 2D raytracing simulations and the diffusive equilibrium density model have been applied to 82 cases of MRWM echoes, observed during August-December of the year 2005 below 5000 km to determine electron and ion density measurements along Earth's magnetic field line. These are the first results of electron and ion density measurements from WM sounding covering L-shells ~1.6-4, a wide range of geomagnetic conditions (Kp 0+ to 7), and during solar minima (F10.2~70-120) in the altitude range 90 km to 4000 km. The electron and ion density profiles obtained from this analysis were compared with in situ measurements on IMAGE (passive recording; electron density (Ne)), DMSP (~850 km; Ne and ions), CHAMP (~350 km; Ne), Alouette (~500-2000 km; Ne and ions), ISIS-1, 2 (~600-3500 km; Ne, ions), AE (~130-2000 km; ions) satellites, bottom side sounding from nearby ionosonde stations (Ne), and those by GCPM (Global Core Plasma Model), IRI-2012 (International Reference Ionosphere). Based on this analysis it is found that: (1) Ne shows a decreasing trend from L-shell 1.6 to 4 on both the day and night sides of the plasmasphere up to altitude ~1000 km, which is also confirmed by the GCPM and IRI-2012 model. (2) Above ~2000 km altitude, GCPM underestimates Ne by ~30-90% relative to RPI passive measurements, WM sounding results. (3) Below 1500 km, the Ne is higher at day side than night side MLT (Magnetic Local Time). Above this altitude, significant MLT dependence of electron density is not seen. (4) Ion densities from WM sounding measurements are within 10-35% of those from the Alouette, AE, and

  7. FUSE Observations of K--M Stars

    NASA Astrophysics Data System (ADS)

    Ake, T. B.; Dupree, A. K.; Linsky, J. L.; Harper, G. M.; Young, P. R.

    2000-12-01

    As part of the FUSE PI program, a representative sample of cool stars is being surveyed in the LWRS (30 x 30 arcsec) aperture. We report on recent observations of three late-type stars, AU Mic (HD 197481, M0 Ve), β Gem (HD 62509, K0 IIIb), and α Ori (HD 39801, M1-2 Ia--Iab). AU Mic and β Gem show strong emission lines of O VI 1032/1037 and C III 977/1176 and weaker lines of C II, N II, N III, S IV, Si III, Si IV, and perhaps Fe III. AU Mic has evidence of He II and S III emission, and β Gem shows S I emission. Differences are seen in line ratios and line profiles between these stars. In α Ori, these features are very weak or non-existent, and Fe II fluorescent lines in the 1100-1150 Å region, pumped by H I Lyman α , are present. Several emission lines are still unidentified in all spectra. Prospects for future cool star observations will be discussed. This work is based on data obtained for the Guaranteed Time Team by the NASA-CNES-CSA FUSE mission operated by the Johns Hopkins University. Financial support to U. S. participants has been provided by NASA contract NAS5-32985.

  8. Summary of Salient Findings of "Natural Attenuation of the Lead Scavengers 1,2-Dibromoethane (EDB) and 1,2-Dichloroethane (1,2-DCA) at Motor Fuel Release Sites and Implications for Risk Management"

    EPA Science Inventory

    Tetra-ethyl lead was widely used in leaded automobile gasoline from 1923 until 1987 (See Figure 1). To prevent lead deposits from fouling the engine, 1,2-dibromoethane (EDB) and 1,2-dichloroethane (1,2-DCA) were added to the gasoline to act as lead scavengers. These compounds r...

  9. Lectin KM+-induced neutrophil haptotaxis involves binding to laminin.

    PubMed

    Ganiko, Luciane; Martins, Antônio R; Freymüller, Edna; Mortara, Renato A; Roque-Barreira, Maria-Cristina

    2005-01-18

    The lectin KM+ from Artocarpus integrifolia, also known as artocarpin, induces neutrophil migration by haptotaxis. The interactions of KM+ with both the extracellular matrix (ECM) and neutrophils depend on the lectin ability to recognize mannose-containing glycans. Here, we report the binding of KM+ to laminin and demonstrate that this interaction potentiates the KM+-induced neutrophil migration. Labeling of lung tissue by KM+ located its ligands on the endothelial cells, in the basement membrane, in the alveolus, and in the interstitial connective tissue. Such labeling was inhibited by 400 mM D-mannose, 10 mM Manalpha1-3[Manalpha1-6]Man or 10 microM peroxidase (a glycoprotein-containing mannosyl heptasaccharide). Laminin is a tissue ligand for KM+, since both KM+ and anti-laminin antibodies not only reacted with the same high molecular mass components of a lung extract, but also determined colocalized labeling in basement membranes of the lung tissue. The relevance of the KM+-laminin interaction to the KM+ property of inducing neutrophil migration was evaluated. The inability of low concentrations of soluble KM+ to induce human neutrophil migration was reversed by coating the microchamber filter with laminin. So, the interaction of KM+ with laminin promotes the formation of a substrate-bound KM+ gradient that is able to induce neutrophil haptotaxis.

  10. MODIS 3km Aerosol Product: Algorithm and Global Perspective

    NASA Technical Reports Server (NTRS)

    Remer, L. A.; Mattoo, S.; Levy, R. C.; Munchak, L.

    2013-01-01

    After more than a decade of producing a nominal 10 km aerosol product based on the dark target method, the MODIS aerosol team will be releasing a nominal 3 km product as part of their Collection 6 release. The new product differs from the original 10 km product only in the manner in which reflectance pixels are ingested, organized and selected by the aerosol algorithm. Overall, the 3 km product closely mirrors the 10 km product. However, the finer resolution product is able to retrieve over ocean closer to islands and coastlines, and is better able to resolve fine aerosol features such as smoke plumes over both ocean and land. In some situations, it provides retrievals over entire regions that the 10 km product barely samples. In situations traditionally difficult for the dark target algorithm, such as over bright or urban surfaces the 3 km product introduces isolated spikes of artificially high aerosol optical depth (AOD) that the 10 km algorithm avoids. Over land, globally, the 3 km product appears to be 0.01 to 0.02 higher than the 10 km product, while over ocean, the 3 km algorithm is retrieving a proportionally greater number of very low aerosol loading situations. Based on collocations with ground-based observations for only six months, expected errors associated with the 3 km land product are determined to be greater than for the 10 km product: 0.05 0.25 AOD. Over ocean, the suggestion is for expected errors to be the same as the 10 km product: 0.03 0.05 AOD. The advantage of the product is on the local scale, which will require continued evaluation not addressed here. Nevertheless, the new 3 km product is expected to provide important information complementary to existing satellite-derived products and become an important tool for the aerosol community.

  11. Neuromuscular characteristics and fatigue during 10 km running.

    PubMed

    Paavolainen, L; Nummela, A; Rusko, H; Häkkinen, K

    1999-11-01

    This study investigated neuromuscular characteristics and fatigue during 10 km running (10 K) performance in well-trained endurance athletes with different distance running capability. Nine high (HC) and ten low (LC) caliber endurance athletes performed the 10 K on a 200 m indoor track, constant velocity lap (CVL, 4.5 m x s(-1)) 5 times during the course of the 10 K and maximal 20 m speed test before (20 m(b)) and after (20 m(a)) the 10 K. Running velocity (V), ground contact times (CT), ground reaction forces (F) and electromyographic activity (EMG) of the leg muscles (vastus lateralis; VL, biceps femoris; BF, gastrocnemius; GA) were measured during 20 m(b), 20 m(a), and CVLs. The 10 K times differed (p<0.001) between HC and LC (36.3+/-1.2 and 39.2+/-2.0 min, respectively) but no differences were observed in 20 m(b) velocity. The 10 K led to significant (p<0.05) decreases in V, F and integrated EMG (IEMG) and increases in CTs of 20 m(a) in both groups. No changes were observed in HC or LC in F and IEMG during the CVLs but HC showed shorter (p<0.05) mean CT of CVLs than LC. A significant correlation (r = -0.56, p<0.05) was observed between the mean CT of CVLs and velocity of 10 K (V10K). Pre-activity of GA in relation to the IEMG of the total contact phase during the CVLs was higher (p<0.05) in HC than LC. The relative IEMGs of VL and GA in the propulsion phase compared to the IEMG of the 20 m(b) were lower (p<0.05) in HC than LC. In conclusion, marked fatigue took place in both HC and LC during the 10 K but the fatigue-induced changes in maximal 20 m run did not differentiate endurance athletes with different V10K. However, a capability to produce force rapidly throughout the 10 K accompanied with optimal preactivation and contact phase activation seem to be important for 10 km running performance in well trained endurance athletes.

  12. Side Elevation, End Elevation, Cross Section, 1/2 Roof Plan, 1/2 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Side Elevation, End Elevation, Cross Section, 1/2 Roof Plan, 1/2 Reflected Plan, 1/2 Floor Plan, 1/2 Reflected Plan - Jack's Mill Covered Bridge, Spanning Henderson Creek, Oquawka, Henderson County, IL

  13. Microphysical Model of the Venus clouds between 40km and 80km

    NASA Astrophysics Data System (ADS)

    McGouldrick, Kevin

    2013-10-01

    I am continuing to adapt the Community Aerosol and Radiation Model for Atmospheres (CARMA) to successfully simulate the multi-layered clouds of Venus. The present version of the one-dimensional model now includes a simple parameterization of the photochemicial production of sulfuric acid around altitudes of 62km, and its thermochemical destruction below cloud base. Photochemical production in the model is limited by the availability of water vapor and insolation. Upper cloud particles are introduced into the model via binary homogeneous nucleation, while the lower and middle cloud particles are created via activation of involatile cloud condensation nuclei. Growth by condensation and coagulation and coalescence are also treated. Mass loadings and particle sizes compare favorably with the in situ observations by the Pioneer Venus Large Probe Particle Size Spectrometer, and mixing ratios of volatiles compare favorably with remotely sensed observations of water vapor and sulfuric acid vapor. This work was supported by the NASA Planetary Atmospheres Program, grant number NNX11AD79G.

  14. Exploring the Benefits of KM Education for LIS Professionals

    ERIC Educational Resources Information Center

    Hazeri, Afsaneh; Martin, Bill; Sarrafzadeh, Maryam

    2009-01-01

    It is to be expected that in a new and emerging discipline like knowledge management (KM) there still will be ambivalence among both LIS educational institutions and their students, as to the need to have KM courses. Investigating the benefits of engaging with these programs might help to clear up this ambiguity. The present paper seeks to shed…

  15. 7 CFR 29.1035 - Mixed color (KM).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together....

  16. 7 CFR 29.1035 - Mixed color (KM).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together....

  17. 7 CFR 29.1035 - Mixed color (KM).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together....

  18. 7 CFR 29.1035 - Mixed color (KM).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together....

  19. 7 CFR 29.1035 - Mixed color (KM).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together....

  20. Hundred lightcurves of sub-km main-belt asteroids

    NASA Astrophysics Data System (ADS)

    Yoshida, F.; Souami, D.; Bouquillon, S.; Nakamura, T.; Dermawan, B.; Yagi, M.; Souchay, J.

    2014-07-01

    We observed a single sky field near opposition and near the ecliptic plane using the Subaru telescope equipped with the Suprime-Cam. Taking advantage of the wide field of view (FOV) for the Suprime-Cam, the plan was to obtain 100 lightcurves of asteroids at the same time. The total observing time interval was about 8 hours on September 2, 2002, with 2-min exposures. We detected 147 moving objects in the single FOV (34'×27') on the Suprime-Cam (see Figure). Of those, 112 detections corresponded to different objects. We used the R filter during almost the entire observing run, but we took a few images with the B filter at the beginning, the middle, and the end of the run. We classified main-belt asteroids into S- and C-complexes with the B-R color of the object (Yoshida & Nakamura 2007). Although we carefully avoided regions of bright stars, the sky in the images taken by Suprime-Cam were actually crowded with faint objects. Therefore, the asteroids overlapped with background stars very often. Thus, it was very difficult to get lightcurves with high accuracy. We modified the GAIA-GBOT (Ground Based Optical Tracking) PIPELINE to measure the position and brightness of each object (Bouquillon et al. 2012). Once the objects were identified and their positions measured in pixel coordinates, the pipeline proceeded to the astrometric calibration and then to the photometric calibrations with the Guide Star Catalog II (Lasker et al. 2008). The pipeline produced time series of photometry for each object. The average brightness of each lightcurve ranged between 19--24 mag. We then estimated the rotational period from the lightcurve of each object. In our presentation, we will show the spin-period distribution of sub- km main-belt asteroids and compare it with that of large main-belt asteroids obtained from the lightcurve catalogue.

  1. 43 CFR 2812.1-2 - Contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Contents. 2812.1-2 Section 2812.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-2 Contents. (a) An individual applicant and each member of...

  2. 43 CFR 2812.1-2 - Contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Contents. 2812.1-2 Section 2812.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-2 Contents. (a) An individual applicant and each member of...

  3. 16 CFR 1.2 - Procedure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Procedure. 1.2 Section 1.2 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE GENERAL PROCEDURES Industry Guidance Advisory Opinions § 1.2 Procedure. (a) Application. The request for advice...

  4. 44 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Definitions. 1.2 Section 1.2... GENERAL RULEMAKING; POLICY AND PROCEDURES General § 1.2 Definitions. (a) Rule or regulation means the...) Significant adverse effects on competition, employment, investment, productivity, innovation, or on...

  5. 43 CFR 2812.1-2 - Contents.

    Code of Federal Regulations, 2012 CFR

    2006-10-01

    ... 43 Public Lands: Interior 2 2006-10-01 2006-10-01 false Contents. 2812.1-2 Section 2812.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-2 Contents. (a) An individual applicant and each member of...

  6. 43 CFR 2812.1-2 - Contents.

    Code of Federal Regulations, 2013 CFR

    1997-10-01

    ... 43 Public Lands: Interior 2 1997-10-01 1997-10-01 false Contents. 2812.1-2 Section 2812.1-2 LAND RESOURCE MANAGEMENT (2000) TRAMROADS AND LOGGING ROADS Over O. and C. and Coos Bay Revested Lands § 2812.1-2 Contents. (a) An individual applicant and each member of any unincorporated association which...

  7. 7 CFR 1.2 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Policy. 1.2 Section 1.2 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.2 Policy. (a) Agencies of USDA shall comply with the time limits set forth in the FOIA and in this subpart for responding to...

  8. 49 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Definitions. 1.2 Section 1.2 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF POWERS AND DUTIES General § 1.2 Definitions. As used in this part, Administrator includes: (a) The Federal Aviation Administrator. (b) The Federal Highway Administrator. (c)...

  9. 7 CFR 1.2 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Policy. 1.2 Section 1.2 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.2 Policy. (a) Agencies of USDA shall comply with the time limits set forth in the FOIA and in this subpart for responding to...

  10. 43 CFR 2812.1-2 - Contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Contents. 2812.1-2 Section 2812.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-2 Contents. (a) An individual applicant and each member of...

  11. 43 CFR 2812.1-2 - Contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Contents. 2812.1-2 Section 2812.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT... Bay Revested Lands § 2812.1-2 Contents. (a) An individual applicant and each member of...

  12. Exploring KM Features of High-Performance Companies

    NASA Astrophysics Data System (ADS)

    Wu, Wei-Wen

    2007-12-01

    For reacting to an increasingly rival business environment, many companies emphasize the importance of knowledge management (KM). It is a favorable way to explore and learn KM features of high-performance companies. However, finding out the critical KM features of high-performance companies is a qualitative analysis problem. To handle this kind of problem, the rough set approach is suitable because it is based on data-mining techniques to discover knowledge without rigorous statistical assumptions. Thus, this paper explored KM features of high-performance companies by using the rough set approach. The results show that high-performance companies stress the importance on both tacit and explicit knowledge, and consider that incentives and evaluations are the essentials to implementing KM.

  13. Role of the transition zone and 660 km discontinuity in mantle dynamics

    NASA Astrophysics Data System (ADS)

    Ringwood, A. E.

    1994-10-01

    of differentiated oceanic lithosphere, with discrete lithological domains of former oceanic crust, former harzburgite and former lherzolite. However, in the upper mantle, these lithologies have been homogenized via convective mixing and partial melting to form a uniform pyrolite composition. Seismic velocity gradients in the heterogeneous mixture of lithologies of the transition zone are higher than they would be in homogeneous pyrolite, because of the survival of clinopyroxene to a depth of about 500 km. This may contribute towards high seismic velocity gradients observed in the transition zone. The behavior during partial melting of heterogeneous lithologies from the transition zone is also quite different from the partial melting of homogeneous pyrolite. The transition zone provides the principal source region for alkaline intraplate basalts world-wide (including ocean island basalts) whereas the homogeneous pyrolite source region of the upper mantle yields mid-ocean ridge basalt magmas.

  14. Marshall Space Flight Center Propulsion Systems Department (PSD) KM Initiative

    NASA Technical Reports Server (NTRS)

    Caraccioli, Paul; Varnadoe, Tom; McCarter, Mike

    2006-01-01

    NASA Marshall Space Flight Center s Propulsion Systems Department (PSD) is four months into a fifteen month Knowledge Management (KM) initiative to support enhanced engineering decision making and analyses, faster resolution of anomalies (near-term) and effective, efficient knowledge infused engineering processes, reduced knowledge attrition, and reduced anomaly occurrences (long-term). The near-term objective of this initiative is developing a KM Pilot project, within the context of a 3-5 year KM strategy, to introduce and evaluate the use of KM within PSD. An internal NASA/MSFC PSD KM team was established early in project formulation to maintain a practitioner, user-centric focus throughout the conceptual development, planning and deployment of KM technologies and capabilities with in the PSD. The PSD internal team is supported by the University of Alabama's Aging Infrastructure Systems Center Of Excellence (AISCE), Intergraph Corporation, and The Knowledge Institute. The principle product of the initial four month effort has been strategic planning of PSD KM implementation by first determining the "as is" state of KM capabilities and developing, planning and documenting the roadmap to achieve the desired "to be" state. Activities undertaken to support the planning phase have included data gathering; cultural surveys, group work-sessions, interviews, documentation review, and independent research. Assessments and analyses have been performed including industry benchmarking, related local and Agency initiatives, specific tools and techniques used and strategies for leveraging existing resources, people and technology to achieve common KM goals. Key findings captured in the PSD KM Strategic Plan include the system vision, purpose, stakeholders, prioritized strategic objectives mapped to the top ten practitioner needs and analysis of current resource usage. Opportunities identified from research, analyses, cultural/KM surveys and practitioner interviews include

  15. Crustal structure of the southern Dead Sea basin derived from project DESIRE wide-angle seismic data

    NASA Astrophysics Data System (ADS)

    Mechie, J.; Abu-Ayyash, K.; Ben-Avraham, Z.; El-Kelani, R.; Qabbani, I.; Weber, M.

    2009-07-01

    As part of the DEad Sea Integrated REsearch project (DESIRE) a 235 km long seismic wide-angle reflection/refraction (WRR) profile was completed in spring 2006 across the Dead Sea Transform (DST) in the region of the southern Dead Sea basin (DSB). The DST with a total of about 107 km multi-stage left-lateral shear since about 18 Ma ago, accommodates the movement between the Arabian and African plates. It connects the spreading centre in the Red Sea with the Taurus collision zone in Turkey over a length of about 1100 km. With a sedimentary infill of about 10 km in places, the southern DSB is the largest pull-apart basin along the DST and one of the largest pull-apart basins on Earth. The WRR measurements comprised 11 shots recorded by 200 three-component and 400 one-component instruments spaced 300 m to 1.2 km apart along the whole length of the E-W trending profile. Models of the P-wave velocity structure derived from the WRR data show that the sedimentary infill associated with the formation of the southern DSB is about 8.5 km thick beneath the profile. With around an additional 2 km of older sediments, the depth to the seismic basement beneath the southern DSB is about 11 km below sea level beneath the profile. Seismic refraction data from an earlier experiment suggest that the seismic basement continues to deepen to a maximum depth of about 14 km, about 10 km south of the DESIRE profile. In contrast, the interfaces below about 20 km depth, including the top of the lower crust and the Moho, probably show less than 3 km variation in depth beneath the profile as it crosses the southern DSB. Thus the Dead Sea pull-apart basin may be essentially an upper crustal feature with upper crustal extension associated with the left-lateral motion along the DST. The boundary between the upper and lower crust at about 20 km depth might act as a decoupling zone. Below this boundary the two plates move past each other in what is essentially a shearing motion. Thermo

  16. The KM phase in semi-realistic heterotic orbifold models

    SciTech Connect

    Giedt, Joel

    2000-07-05

    In string-inspired semi-realistic heterotic orbifolds models with an anomalous U(1){sub X},a nonzero Kobayashi-Masakawa (KM) phase is shown to arise generically from the expectation values of complex scalar fields, which appear in nonrenormalizable quark mass couplings. Modular covariant nonrenormalizable superpotential couplings are constructed. A toy Z{sub 3} orbifold model is analyzed in some detail. Modular symmetries and orbifold selection rules are taken into account and do not lead to a cancellation of the KM phase. We also discuss attempts to obtain the KM phase solely from renormalizable interactions.

  17. Making minor rural road networks safer: The effects of 60 km/h-zones.

    PubMed

    Jaarsma, Rinus; Louwerse, Robert; Dijkstra, Atze; de Vries, Jasper; Spaas, Jac-Paul

    2011-07-01

    For safety reasons a maximum speed limit of 60km/h has been applied to minor rural roads in the Netherlands since 1998. To support this structurally, a part of these roads have also received additional physical measures in a so-called "low cost design" that is expected to reduce the number of traffic casualties by 10-20%. This measure has been implemented as much as possible in an area oriented way. To measure the design's effectivity, road safety in 20 specific rural areas was studied for 5 years before changes were implemented and, on average, 3.5 years thereafter. The study examined 851km of roads, and a control study was done on 2105km of comparable roads with a speed limit of 80km/h. Both the study and the control roads are managed by water boards. Results show that the measures implemented on the roads in the 60km/h-zones had statistically significant effects (p<0.05) on casualty accidents (-24% overall), especially at intersections (-44%). This high reduction is probably caused by the concentration of technical interventions at intersections. Both outcomes are somewhat higher than previously expected and are comparable with the outcome of a meta-analysis of safety effects on area-wide urban traffic calming schemes. However, the cost-effectiveness ratio of the 60km/h zones measures (€33,000 per prevented KSI-casualty) is much more favourable than the ratio in urban 30km/h-zones (€86,000 per prevented KSI-casualty).

  18. The -145 km/s Absorption System of Eta Carinae

    NASA Technical Reports Server (NTRS)

    Vieira, G.; Gull, Theodore R.; Danks, A.; Johansson, S.

    2002-01-01

    With the STIS E230H mode (R approx. 118,000), we have identified about twenty absorption components in line of sight from Eta Carinae. Two components, one at -513 km/s and another at -145 km/s, are quite different in character from the others, mostly at intermediate velocities. The -145 km/s component is significantly wider in fwhm, is seen in many more species, and the lower level can be above 20,000/cm, well above the 2000/cm noted in the -513 km/s component. In the spectral region from 2400 to 3160A, approximately 500 absorption lines have been identified. In this poster, we will present line identifications and atomic parameters of the measured lines, hopefully providing insight as to what levels are being excited and by what processes. Observations were accomplished through STScI under proposal 9242. Funding is through the STIS GTO resources.

  19. High energy neutrino detection with KM3NeT

    NASA Astrophysics Data System (ADS)

    Migliozzi, Pasquale; KM3NeT Collaboration

    2016-05-01

    The KM3NeT Collaboration has started the construction of a next generation high-energy neutrino telescope in the Mediterranean Sea: the largest and most sensitive neutrino research infrastructure. The full KM3NeT detector will be a several cubic kilometres distributed, networked infrastructure. In Italy, off the coast of Capo Passero, and in France, off the coast of Toulon. Thanks to its location in the Northern hemisphere and to its large instrumented volume, KM3NeT will be the optimal instrument to search for neutrinos from the Southern sky and in particular from the Galactic plane, thus making it complementary to IceCube. In this work the technologically innovative component of the detector, the status of construction and the first results from prototypes of the KM3NeT detector will be described as well as its capability to discover neutrino sources are reported.

  20. Akeno 20 km (2) air shower array (Akeno Branch)

    NASA Technical Reports Server (NTRS)

    Teshima, M.; Ohoka, H.; Matsubara, Y.; Hara, T.; Hatano, Y.; Hayashida, N.; He, C. X.; Honda, M.; Ishikawa, F.; Kamata, K.

    1985-01-01

    As the first stage of the future huge array, the Akeno air shower array was expanded to about 20 sq. km. by adding 19 scintillation detectors of 2.25 sq m area outside the present 1 sq. km. Akeno array with a new data collection system. These detectors are spaced about 1km from each other and connected by two optical fiber cables. This array has been in partial operation from 8th, Sep. 1984 and full operation from 20th, Dec. 1984. 20 sq m muon stations are planned to be set with 2km separation and one of them is now under construction. The origin of the highest energy cosmic rays is studied.

  1. How does music aid 5 km of running?

    PubMed

    Bigliassi, Marcelo; León-Domínguez, Umberto; Buzzachera, Cosme F; Barreto-Silva, Vinícius; Altimari, Leandro R

    2015-02-01

    This research investigated the effects of music and its time of application on a 5-km run. Fifteen well-trained male long-distance runners (24.87 ± 2.47 years; 78.87 ± 10.57 kg; 178 ± 07 cm) participated in this study. Five randomized experimental conditions during a 5-km run on an official track were tested (PM: motivational songs, applied before 5 km of running; SM: slow motivational songs, applied during 5 km of running; FM: fast and motivational songs, applied during 5 km of running; CS: calm songs, applied after 5 km of running; CO: control condition). Psychophysiological assessments were performed before (functional near-infrared spectroscopy, heart rate variability [HRV], valence, and arousal), during (performance time, heart rate, and rate of perceived exertion [RPE]), and after (mood, RPE, and HRV) tests. The chosen songs were considered pleasurable and capable of activating. Furthermore, they activated the 3 assessed prefrontal cortex (PFC) areas (medial, right dorsolateral, and left dorsolateral) similarly, generating positive emotional consequences by autonomous system analysis. The first 800 m was accomplished faster for SM and FM compared with other conditions (p ≤ 0.05); moreover, there was a high probability of improving running performance when music was applied (SM: 89%; FM: 85%; PM: 39%). Finally, music was capable of accelerating vagal tonus after 5 km of running with CS (p ≤ 0.05). In conclusion, music was able to activate the PFC area, minimize perceptions, improve performance, and accelerate recovery during 5 km of running.

  2. How does music aid 5 km of running?

    PubMed

    Bigliassi, Marcelo; León-Domínguez, Umberto; Buzzachera, Cosme F; Barreto-Silva, Vinícius; Altimari, Leandro R

    2015-02-01

    This research investigated the effects of music and its time of application on a 5-km run. Fifteen well-trained male long-distance runners (24.87 ± 2.47 years; 78.87 ± 10.57 kg; 178 ± 07 cm) participated in this study. Five randomized experimental conditions during a 5-km run on an official track were tested (PM: motivational songs, applied before 5 km of running; SM: slow motivational songs, applied during 5 km of running; FM: fast and motivational songs, applied during 5 km of running; CS: calm songs, applied after 5 km of running; CO: control condition). Psychophysiological assessments were performed before (functional near-infrared spectroscopy, heart rate variability [HRV], valence, and arousal), during (performance time, heart rate, and rate of perceived exertion [RPE]), and after (mood, RPE, and HRV) tests. The chosen songs were considered pleasurable and capable of activating. Furthermore, they activated the 3 assessed prefrontal cortex (PFC) areas (medial, right dorsolateral, and left dorsolateral) similarly, generating positive emotional consequences by autonomous system analysis. The first 800 m was accomplished faster for SM and FM compared with other conditions (p ≤ 0.05); moreover, there was a high probability of improving running performance when music was applied (SM: 89%; FM: 85%; PM: 39%). Finally, music was capable of accelerating vagal tonus after 5 km of running with CS (p ≤ 0.05). In conclusion, music was able to activate the PFC area, minimize perceptions, improve performance, and accelerate recovery during 5 km of running. PMID:25029009

  3. Wide Angle Movie

    NASA Technical Reports Server (NTRS)

    1999-01-01

    This brief movie illustrates the passage of the Moon through the Saturn-bound Cassini spacecraft's wide-angle camera field of view as the spacecraft passed by the Moon on the way to its closest approach with Earth on August 17, 1999. From beginning to end of the sequence, 25 wide-angle images (with a spatial image scale of about 14 miles per pixel (about 23 kilometers)were taken over the course of 7 and 1/2 minutes through a series of narrow and broadband spectral filters and polarizers, ranging from the violet to the near-infrared regions of the spectrum, to calibrate the spectral response of the wide-angle camera. The exposure times range from 5 milliseconds to 1.5 seconds. Two of the exposures were smeared and have been discarded and replaced with nearby images to make a smooth movie sequence. All images were scaled so that the brightness of Crisium basin, the dark circular region in the upper right, is approximately the same in every image. The imaging data were processed and released by the Cassini Imaging Central Laboratory for Operations (CICLOPS)at the University of Arizona's Lunar and Planetary Laboratory, Tucson, AZ.

    Photo Credit: NASA/JPL/Cassini Imaging Team/University of Arizona

    Cassini, launched in 1997, is a joint mission of NASA, the European Space Agency and Italian Space Agency. The mission is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Office of Space Science, Washington DC. JPL is a division of the California Institute of Technology, Pasadena, CA.

  4. Tannase Production by Penicillium Atramentosum KM under SSF and its Applications in Wine Clarification and Tea Cream Solubilization.

    PubMed

    Selwal, Manjit K; Yadav, Anita; Selwal, Krishan K; Aggarwal, N K; Gupta, Ranjan; Gautam, S K

    2011-01-01

    Tannin acyl hydrolase commonly known as tannase is an industrially important enzyme having a wide range of applications, so there is always a scope for novel tannase with better characteristics. A newly isolated tannase-yielding fungal strain identified as Penicillium atramentosum KM was used for tannase production under solid-state fermentation (SSF) using different agro residues like amla (Phyllanthus emblica), ber (Zyzyphus mauritiana), jamun (Syzygium cumini), Jamoa (Eugenia cuspidate) and keekar (Acacia nilotica) leaves. Among these substrates, maximal extracellular tannase production i.e. 170.75 U/gds and 165.56 U/gds was obtained with jamun and keekar leaves respectively at 28ºC after 96 h. A substrate to distilled water ratio of 1:2 (w/v) was found to be the best for tannase production. Supplementation of sodium nitrate (NaNO3) as nitrogen source had enhanced tannase production both in jamun and keekar leaves. Applications of the enzyme were studied in wine clarification and tea cream solubilization. It resulted in 38.05% reduction of tannic acid content in case of jamun wine, 43.59% reduction in case of grape wine and 74% reduction in the tea extract after 3 h at 35°C. PMID:24031644

  5. Local fluctuations of ozone from 16 km to 45 km deduced from in situ vertical ozone profile

    NASA Technical Reports Server (NTRS)

    Moreau, G.; Robert, C.

    1994-01-01

    A vertical ozone profile obtained by an in situ ozone sonde from 16 km to 45 km, has allowed to observe local ozone concentration variations. These variations can be observed, thanks to a fast measurement system based on a UV absorption KrF excimer laser beam in a multipass cell. Ozone standard deviation versus altitude calculated from the mean is derived. Ozone variations or fluctuations are correlated with the different dynamic zones of the stratosphere.

  6. 23 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Definitions. 1.2 Section 1.2 Highways FEDERAL HIGHWAY... shall have the following meaning: Administrator. The Federal Highway Administrator. Advertising policy... laws, heretofore or hereafter enacted, relating to Federal aid for highways. Latest available...

  7. 23 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Definitions. 1.2 Section 1.2 Highways FEDERAL HIGHWAY... shall have the following meaning: Administrator. The Federal Highway Administrator. Advertising policy... laws, heretofore or hereafter enacted, relating to Federal aid for highways. Latest available...

  8. 23 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Definitions. 1.2 Section 1.2 Highways FEDERAL HIGHWAY... shall have the following meaning: Administrator. The Federal Highway Administrator. Advertising policy... laws, heretofore or hereafter enacted, relating to Federal aid for highways. Latest available...

  9. 23 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Definitions. 1.2 Section 1.2 Highways FEDERAL HIGHWAY... shall have the following meaning: Administrator. The Federal Highway Administrator. Advertising policy... laws, heretofore or hereafter enacted, relating to Federal aid for highways. Latest available...

  10. 23 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Definitions. 1.2 Section 1.2 Highways FEDERAL HIGHWAY... shall have the following meaning: Administrator. The Federal Highway Administrator. Advertising policy... laws, heretofore or hereafter enacted, relating to Federal aid for highways. Latest available...

  11. 24 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... participates in carrying out such program or activity (such as a redeveloper in the Urban Renewal Program... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Definitions. 1.2 Section 1.2 Housing and Urban Development Office of the Secretary, Department of Housing and Urban...

  12. 24 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... participates in carrying out such program or activity (such as a redeveloper in the Urban Renewal Program... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Definitions. 1.2 Section 1.2 Housing and Urban Development Office of the Secretary, Department of Housing and Urban...

  13. 24 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... participates in carrying out such program or activity (such as a redeveloper in the Urban Renewal Program... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Definitions. 1.2 Section 1.2 Housing and Urban Development Office of the Secretary, Department of Housing and Urban...

  14. 24 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... participates in carrying out such program or activity (such as a redeveloper in the Urban Renewal Program... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Definitions. 1.2 Section 1.2 Housing and Urban Development Office of the Secretary, Department of Housing and Urban...

  15. 24 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... participates in carrying out such program or activity (such as a redeveloper in the Urban Renewal Program... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Definitions. 1.2 Section 1.2 Housing and Urban Development Office of the Secretary, Department of Housing and Urban...

  16. 8 CFR 1.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Definitions. 1.2 Section 1.2 Aliens and... alien means an applicant for admission coming or attempting to come into the United States at a port-of-entry, or an alien seeking transit through the United States at a port-of-entry, or an alien...

  17. 45 CFR 1210.1-2 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Scope. 1210.1-2 Section 1210.1-2 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VISTA... separation of any Trainee or Volunteer. Separate procedures, as detailed in the VISTA Handbook,...

  18. General synthesis of substituted 1,2-dihydropyridines.

    PubMed

    Tejedor, David; Cotos, Leandro; Méndez-Abt, Gabriela; García-Tellado, Fernando

    2014-11-01

    A general and practical metal-free protocol for the synthesis of 1,2-dihydropyridines with wide structural/functional diversity at the ring and featuring mono, double, or spiro substitution at the sp(3) position is described. The protocol entails a microwave-assisted domino reaction of a propargyl vinyl ether (secondary or tertiary) and a primary amine (aliphatic or aromatic) in toluene or methanol.

  19. The KM3NeT Digital Optical Module

    NASA Astrophysics Data System (ADS)

    Vivolo, Daniele

    2016-04-01

    KM3NeT is a European deep-sea multidisciplinary research infrastructure in the Mediterranean Sea. It will host a km3-scale neutrino telescope and dedicated instruments for long-term and continuous measurements for Earth and Sea sciences. The KM3NeT neutrino telescope is a 3-dimensional array of Digital Optical Modules, suspended in the sea by means of vertical string structures, called Detection Units, supported by two pre-stretched Dyneema ropes, anchored to the seabed and kept taut with a system of buoys. The Digital Optical Module represents the active part of the neutrino telescope. It is composed by a 17-inch, 14 mm thick borosilicate glass (Vitrovex) spheric vessel housing 31 photomultiplier tubes with 3-inch photocathode diameter and the associated front-end and readout electronics. The technical solution adopted for the KM3NeT optical modules is characterized by an innovative design, considering that existing neutrino telescopes, Baikal, IceCube and ANTARES, all use large photomultipliers, typically with a diameter of 8″ or 10″. It offers several advantages: higher sensitive surface (1260 cm2), weaker sensitivity to Earth's magnetic field, better distinction between single-photon and multi-photon events (photon counting) and directional information with an almost isotropic field of view. In this contribution the design and the performance of the KM3NeT Digital Optical Modules are discussed, with a particular focus on enabling technologies and integration procedure.

  20. Gravity Waves Near 300 km Over the Polar Caps

    NASA Technical Reports Server (NTRS)

    Johnson, F. S.; Hanson, W. B.; Hodges, R. R.; Coley, W. R.; Carignan, G. R.; Spencer, N. W.

    1995-01-01

    Distinctive wave forms in the distributions of vertical velocity and temperature of both neutral particles and ions are frequently observed from Dynamics Explorer 2 at altitudes above 250 km over the polar caps. These are interpreted as being due to internal gravity waves propagating in the neutral atmosphere. The disturbances characterized by vertical velocity perturbations of the order of 100 m/s and horizontal wave lengths along the satellite path of about 500 km. They often extend across the entire polar cap. The associated temperature perturbations indicate that the horizontal phase progression is from the nightside to the dayside. Vertical displacements are inferred to be of the order of 10 km and the periods to be of the order of 10(exp 3) s. The waves must propagate in the neutral atmosphere, but they usually are most clearly recognizable in the observations of ion vertical velocity and ion temperature. By combining the neutral pressure calculated from the observed neutral concentration and temperature with the vertical component of the neutral velocity, an upward energy flux of the order of 0.04 erg/sq cm-s at 250 km has been calculated, which is about equal to the maximum total solar ultraviolet heat input above that altitude. Upward energy fluxes calculated from observations on orbital passes at altitudes from 250 to 560 km indicate relatively little attenuation with altitude.

  1. Seismic Wide-Angle Reflection / Refraction Profiling from the DESIRE Project Reveals the Deep Structure Across the Southern Dead Sea Basin

    NASA Astrophysics Data System (ADS)

    Weber, M.; Mechie, J.; Ab-Ayyash, K.; Ben-Avraham, Z.; El-Kelani, R.; Qabbani, I.; DESIRE Group

    2007-12-01

    As part of the DESIRE project a 240 km long seismic wide-angle reflection / refraction (WRR) profile was completed in spring 2006 across the Dead Sea Transform (DST) in the region of the southern Dead Sea basin. The DST with a total of about 105 km multi-stage left-lateral shear since about 18 Ma ago, accommodates the movement between the Arabian and African plates. It connects the spreading centre in the Red Sea with the Taurus collision zone in Turkey over a length of about 1100 km. With a sedimentary infill of about 10 km in places, the southern Dead Sea basin is the largest pull-apart basin along the DST and one of the largest pull-apart basins on Earth. The WRR measurements comprised 11 shots recorded by 200 three-component and 400 one- component instruments spaced 300 m to 1.2 km apart along the whole length of the E-W trending profile. Models of the P-wave velocity structure derived from the WRR data show that the sedimentary infill associated with the formation of the southern Dead Sea basin is about 8.5 km thick beneath the profile. With around an additional 2 km of older sediments, the depth to the seismic basement beneath the southern Dead Sea basin is about 11 km below sea level beneath the profile. In contrast, the interfaces below about 20 km depth, including the top of the lower crust and the Moho, show less than 3 km variation in depth beneath the profile as it crosses the southern Dead Sea basin. Thus the Dead Sea pull-apart basin is essentially an upper crustal feature with N-S upper crustal extension associated with the left-lateral motion along the DST. The boundary between the upper and lower crust at about 20 km depth must act as a decoupling zone. Thermo-mechanical modelling of the Dead Sea basin supports such a scenario.

  2. The -145 km/S Absorption System of Eta Carinae

    NASA Technical Reports Server (NTRS)

    Vieira, G.; Gull, T. R.; Danks, A.; Johansson, S.

    2002-01-01

    With the STIS E230H mode (R-118,000) , we have identified about twenty absorption components in line of sight from Eta Carinae. Two components, one at -513 km/s and another at -145 W s , are quite different in character from the others, mostly at intermediate velocities. The -145 km/s component is significantly wider in fwhm, is seen in many more species, and the lower level can be above 20,000/cm, well above the 2000/cm noted in the -513 km/s component. In the spectral region from 2400 to 3160A, approximately 500 absorption lines have been identified. In this poster, we will present line identifications and atomic parameters of the measured lines, hopefully providing insight as to what levels are being excited and by what processes.

  3. Potential of KM+ lectin in immunization against Leishmania amazonensis infection.

    PubMed

    Teixeira, Clarissa R; Cavassani, Karen A; Gomes, Regis B; Teixeira, Maria Jania; Roque-Barreira, Maria-Cristina; Cavada, Benildo S; da Silva, João Santana; Barral, Aldina; Barral-Netto, Manoel

    2006-04-01

    In the present study we evaluated Canavalia brasiliensis (ConBr), Pisum arvense (PAA) and Artocarpus integrifolia (KM+) lectins as immunostimulatory molecules in vaccination against Leishmania amazonensis infection. Although they induced IFN-gamma production, the combination of the lectins with SLA antigen did not lead to lesion reduction. However, parasite load was largely reduced in mice immunized with KM+ lectin and SLA. KM+ induced a smaller inflammatory reaction in the air pouch model and was able to inhibit differentiation of dendritic cells (BMDC), but to induce maturation by enhancing the expression of MHC II, CD80 and CD86. These observations indicate the modulatory role of plant lectins in leishmaniasis vaccination may be related to their action on the initial innate response.

  4. Seismological detection of "730-km" discontinuity beneath Japan subduction zone

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Park, J. J.; Karato, S. I.

    2015-12-01

    Because the mantle transition zone likely contains a large amount of water (Karato, 2011; Pearson et al., 2014), vertical material transport across the transition would cause partial melting that may produce seismic signals above and/or below the transition zone. Schmandt et al. (2014) observed a seismic low-velocity zone (LVZ) at the top of the lower mantle (~730 km) beneath the southwestern US, arguing for dehydration melting due to downward flow across the 670-km discontinuity (670) from the transition zone. These authors further proposed a correlation between seismic velocity reductions and the direction of water transport, in which LVZ at ~730 km indicates materials moving downward from the transition zone, while the lack of LVZ at this depth would suggest an upward flow of mantle materials. Other regions also need to be investigated to confirm the correlation between this seismic feature and mantle water transport. We test their model by detecting "730-km" discontinuity beneath the Japan subduction zone using frequency-dependent receiver functions. In addition, water transport above the 410-km discontinuity (410) also plays an important role in global water circulation (Bercovici and Karato, 2003). Seismological studies (e.g. Courtier and Revenaugh, 2007; Schaeffer and Bostock, 2010) have observed LVZs above the 410, which might be caused by dehydration melting due to the upwelling of hydrated materials across the 410-km discontinuity from the transition zone. In this study, we also detect potential LVZs above 410 to establish a correlation between seismic velocity drop and flow direction. Around the Japan subduction zone, our preliminary results show evidence of low velocity zones below 670 in regions where stagnant slab is present for a substantial amount of time but not in other regions suggesting a variety of vertical mass transport in this region. Key words: transition zone, water transport, subduction zone, melting, receiver functions

  5. Simulation of CO2 release at 800 km altitude

    NASA Astrophysics Data System (ADS)

    Setayesh, A.

    1993-08-01

    The SOCRATES contamination-interaction code has been used to simulate the reactions of 0 + CO2 yields CO2(v) + O, O + CO2 - CO(v) + O2, and CO2 + H - CO + OH(v) at an altitude of 800 km in both ram and wake directions of the spacecraft. These simulations show that the radiation from these reactions can be measurable for the parameters which have been used in these calculations. The investigation carries out the simulations as much as 30 km from the spacecraft. The radiative intensity of CO(v) and OH(v) show the highest and lowest, respectively.

  6. Cascade sensitivity studies for KM3NeT

    NASA Astrophysics Data System (ADS)

    Fusco, Luigi Antonio

    2016-07-01

    KM3NeT is a future research infrastructure in the deep seas of the Mediterranean housing a large scale neutrino telescope. The first phase of construction of the telescope has started. Next step is an intermediate phase realising a detector volume of about one-third of the final detector volume. We report on calculations of the sensitivity of the KM3NeT detector to showering neutrino events, the strategy to optimise the detector to a cosmic neutrino flux analogous to the one reported by the IceCube Collaboration and the results of this strategy applied to the intermediate phase detector.

  7. From NEMO to KM3NeT-Italy

    NASA Astrophysics Data System (ADS)

    Nicolau, Carlo A.

    2014-04-01

    The KM3NeT-Italy Collaboration has entered the production stage of an 8 tower apparatus that will be deployed at about 100 km off the Sicily coast. The architecture of the system is based on the NEMO Phase2 prototype tower which is taking data since the deployment in March 2013. In order to optimize production costs, power consumption, and usability, some components have been re-engineered by taking advantage of the previously gained experience and technological progress. The aim of this contribution is to give an overview of the main features that characterize the new apparatus.

  8. Low-velocity zone atop the 410-km seismic discontinuity in the northwestern United States.

    PubMed

    Song, Teh-Ru Alex; Helmberger, Don V; Grand, Stephen P

    2004-02-01

    The seismic discontinuity at 410 km depth in the Earth's mantle is generally attributed to the phase transition of (Mg,Fe)2SiO4 (refs 1, 2) from the olivine to wadsleyite structure. Variation in the depth of this discontinuity is often taken as a proxy for mantle temperature owing to its response to thermal perturbations. For example, a cold anomaly would elevate the 410-km discontinuity, because of its positive Clapeyron slope, whereas a warm anomaly would depress the discontinuity. But trade-offs between seismic wave-speed heterogeneity and discontinuity topography often inhibit detailed analysis of these discontinuities, and structure often appears very complicated. Here we simultaneously model seismic refracted waves and scattered waves from the 410-km discontinuity in the western United States to constrain structure in the region. We find a low-velocity zone, with a shear-wave velocity drop of 5%, on top of the 410-km discontinuity beneath the northwestern United States, extending from southwestern Oregon to the northern Basin and Range province. This low-velocity zone has a thickness that varies from 20 to 90 km with rapid lateral variations. Its spatial extent coincides with both an anomalous composition of overlying volcanism and seismic 'receiver-function' observations observed above the region. We interpret the low-velocity zone as a compositional anomaly, possibly due to a dense partial-melt layer, which may be linked to prior subduction of the Farallon plate and back-arc extension. The existence of such a layer could be indicative of high water content in the Earth's transition zone.

  9. X-1-2 on ramp

    NASA Technical Reports Server (NTRS)

    1951-01-01

    The Bell Aircraft Corporation X-1-2 aircraft on the ramp at NACA High Speed Flight Research Station located on the South Base of Muroc Army Air Field in 1947. The X-1-2 flew until October 23, 1951, completing 74 glide and powered flights with nine different pilots. The aircraft has white paint and the NACA tail band. The black Xs are reference markings for tracking purposes. They were widely used on NACA aircraft in the early 1950s. There were five versions of the Bell X-1 rocket-powered research aircraft that flew at the NACA High-Speed Flight Research Station, Edwards, California. The bullet-shaped X-1 aircraft were built by Bell Aircraft Corporation, Buffalo, N.Y. for the U.S. Army Air Forces (after 1947, U.S. Air Force) and the National Advisory Committee for Aeronautics (NACA). The X-1 Program was originally designated the XS-1 for EXperimental Sonic. The X-1's mission was to investigate the transonic speed range (speeds from just below to just above the speed of sound) and, if possible, to break the 'sound barrier.' Three different X-1s were built and designated: X-1-1, X-1-2 (later modified to become the X-1E), and X-1-3. The basic X-1 aircraft were flown by a large number of different pilots from 1946 to 1951. The X-1 Program not only proved that humans could go beyond the speed of sound, it reinforced the understanding that technological barriers could be overcome. The X-1s pioneered many structural and aerodynamic advances including extremely thin, yet extremely strong wing sections; supersonic fuselage configurations; control system requirements; powerplant compatibility; and cockpit environments. The X-1 aircraft were the first transonic-capable aircraft to use an all-moving stabilizer. The flights of the X-1s opened up a new era in aviation. The first X-1 was air-launched unpowered from a Boeing B-29 Superfortress on Jan. 25, 1946. Powered flights began in December 1946. On Oct. 14, 1947, the X-1-1, piloted by Air Force Captain Charles 'Chuck' Yeager

  10. 45 CFR 1211.1-2 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-2 Applicability. This part applies to all volunteers enrolled under part A of title I of the Domestic Volunteer Service Act of 1973, as amended, Pub. L. 93-113, (42...

  11. 45 CFR 1211.1-2 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-2 Applicability. This part applies to all volunteers enrolled under part A of title I of the Domestic Volunteer Service Act of 1973, as amended, Pub. L. 93-113, (42...

  12. Cloaking spin-(1/2) matter waves

    SciTech Connect

    Lin, De-Hone

    2010-06-15

    A physical construct for the cloaking of relativistic spin-(1/2) matter waves is proposed. It is shown that when the effective energy and mass of relativistic spin-(1/2) particles moving in an effective vector field in a spherical shell are controlled, their matter waves can be perfectly guided through the shell without any distortion or loss; that is, the construct provides a three-dimensional cloaking shell for relativistic spin-(1/2) matter waves. The proposal serves as the basis for some interesting applications such as providing a method to guide the matter waves of spin particles and an ideal setup to exhibit spin-spin interactions as well as perfect quantum interferences of some global effects in spin-(1/2) matter waves.

  13. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

    PubMed Central

    Meng, Zhipeng; Moroishi, Toshiro; Mottier-Pavie, Violaine; Plouffe, Steven W.; Hansen, Carsten G.; Hong, Audrey W.; Park, Hyun Woo; Mo, Jung-Soon; Lu, Wenqi; Lu, Shicong; Flores, Fabian; Yu, Fa-Xing; Halder, Georg; Guan, Kun-Liang

    2015-01-01

    The Hippo pathway plays a central role in tissue homoeostasis, and its dysregulation contributes to tumorigenesis. Core components of the Hippo pathway include a kinase cascade of MST1/2 and LATS1/2 and the transcription co-activators YAP/TAZ. In response to stimulation, LATS1/2 phosphorylate and inhibit YAP/TAZ, the main effectors of the Hippo pathway. Accumulating evidence suggests that MST1/2 are not required for the regulation of YAP/TAZ. Here we show that deletion of LATS1/2 but not MST1/2 abolishes YAP/TAZ phosphorylation. We have identified MAP4K family members—Drosophila Happyhour homologues MAP4K1/2/3 and Misshapen homologues MAP4K4/6/7—as direct LATS1/2-activating kinases. Combined deletion of MAP4Ks and MST1/2, but neither alone, suppresses phosphorylation of LATS1/2 and YAP/TAZ in response to a wide range of signals. Our results demonstrate that MAP4Ks act in parallel to and are partially redundant with MST1/2 in the regulation of LATS1/2 and YAP/TAZ, and establish MAP4Ks as components of the expanded Hippo pathway. PMID:26437443

  14. Body Composition Measurements of 161-km Ultramarathon Participants

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This study compares body composition characteristics with performance among participants in a 161-km trail ultramarathon. Height, mass, and percent body fat from bioimpedence spectroscopy were measured on 72 starters. Correlation analyses were used to compare body characteristics with finish time, ...

  15. The -145 km/s Absorption System of Eta Carinae

    NASA Astrophysics Data System (ADS)

    Vieira, G. L.; Gull, T. R.; Danks, A. C.; Johansson, S.

    2002-12-01

    With the STIS E230H mode (R 118,000), we have identified about twenty absorption components in line of sight from Eta Carinae. Two components, one at -513 km/s and another at -145 km/s, are quite different in character from the others, mostly at intermediate velocities (See adjacent posters by T. Gull and A. Danks). The -145 km/s component is significantly wider in fwhm, is seen in many more species, and the lower level can be above 20,000 cm-1, well above the 2000 cm-1 noted in the -513 km/s component. In the spectral region from 2400 to 3160A, approximately 500 absorption lines have been identified. In this poster, we will present line identifications and atomic parameters of the measured lines, hopefully providing insight as to what levels are being excited and by what processes. Observations were accomplished through STScI under proposal 9242 (Danks, P.I.). Funding is through the STIS GTO resources.

  16. Models of earth's atmosphere (90 to 2500 km)

    NASA Technical Reports Server (NTRS)

    1973-01-01

    This monograph replaces a monograph on the upper atmosphere which was a computerized version of Jacchia's model. The current model has a range from 90 to 2500 km. In addition to the computerized model, a quick-look prediction method is given that may be used to estimate the density for any time and spatial location without using a computer.

  17. Gravity wave vertical energy flux at 95 km

    NASA Technical Reports Server (NTRS)

    Jacob, P. G.; Jacka, F.

    1985-01-01

    A three-field photometer (3FP) located at Mt. Torrens near Adelaide, is capable of monitoring different airglow emissions from three spaced fields in the sky. A wheel containing up to six different narrow bandpass interference filters can be rotated, allowing each of the filters to be sequentially placed into each of the three fields. The airglow emission of interest is the 557.7 nm line which has an intensity maximum at 95 km. Each circular field of view is located at the apexes of an equilateral triangle centered on zenith with diameters of 5 km and field separations of 13 km when projected to the 95-km level. The sampling period was 30 seconds and typical data lengths were between 7 and 8 hours. The analysis and results from the interaction of gravity waves on the 557.7 nm emission layer are derived using an atmospheric model similar to that proposed by Hines (1960) where the atmosphere is assumed isothermal and perturbations caused by gravity waves are small and adiabatic, therefore, resulting in linearized equations of motion. In the absence of waves, the atmosphere is also considered stationary. Thirteen nights of quality data from January 1983 to October 1984, covering all seasons, are used in this analysis.

  18. The Lunar-wide Effects of the Formation of Basins on the Megaregolith

    NASA Technical Reports Server (NTRS)

    Petro, . E.; Pieters, C. M.

    2005-01-01

    The surface of the Moon underwent an intense bombardment during the first approx.700 my of it s history (e.g. [1]). During this time at least 43 basins [1,2] and countless smaller craters were formed across the entire surface [1,3]. A quantitative assessment of the regolith as formed and modified by basins is discussed here. The formation of the basins (craters >300km in diameter) caused a significant amount of material to be excavated and redistributed across the surface of the Moon [4,5,6,7]. The material excavated by each individual basin was deposited and laterally mixed with the surrounding surface. This resulted in the development of a lunar-wide mixed zone of fragmented material, several kilometers thick [5,8,9]. This mixed zone was developed further by subsequent impacts resulting in a fragmental zone 1-2km thick called the megaregolith [10]. The initial zone of mixed material formed by the basins is not expected to be uniform across the surface of the Moon because of the varied size and random distribution of the basins. The main topographic ring of the 43 basins discussed by Wilhelms and Spudis [1,2] are illustrated in Figure 1.

  19. Fact Sheet for KM200 Front-end Electronics

    SciTech Connect

    Ianakiev, Kiril Dimitrov; Iliev, Metodi; Swinhoe, Martyn Thomas

    2015-07-08

    The KM200 device is a versatile, configurable front-end electronics boards that can be used as a functional replacement for Canberra’s JAB-01 boards based on the Amptek A-111 hybrid chip, which continues to be the preferred choice of electronics for large number of the boards in junction boxes of multiplicity counters that process the signal from an array of 3He detectors. Unlike the A-111 chip’s fixed time constants and sensitivity range, the shaping time and sensitivity of the new KM200 can be optimized for demanding applications such as spent fuel, and thus could improve the safeguards measurements of existing systems where the A-111 or PDT electronics does not perform well.

  20. Remote (250 km) Fiber Bragg Grating Multiplexing System

    PubMed Central

    Fernandez-Vallejo, Montserrat; Rota-Rodrigo, Sergio; Lopez-Amo, Manuel

    2011-01-01

    We propose and demonstrate two ultra-long range fiber Bragg grating (FBG) sensor interrogation systems. In the first approach four FBGs are located 200 km from the monitoring station and a signal to noise ratio of 20 dB is obtained. The second improved version is able to detect the four multiplexed FBGs placed 250 km away, offering a signal to noise ratio of 6–8 dB. Consequently, this last system represents the longest range FBG sensor system reported so far that includes fiber sensor multiplexing capability. Both simple systems are based on a wavelength swept laser to scan the reflection spectra of the FBGs, and they are composed by two identical-lengths optical paths: the first one intended to launch the amplified laser signal by means of Raman amplification and the other one is employed to guide the reflection signal to the reception system. PMID:22164101

  1. Remote (250 km) fiber Bragg grating multiplexing system.

    PubMed

    Fernandez-Vallejo, Montserrat; Rota-Rodrigo, Sergio; Lopez-Amo, Manuel

    2011-01-01

    We propose and demonstrate two ultra-long range fiber Bragg grating (FBG) sensor interrogation systems. In the first approach four FBGs are located 200 km from the monitoring station and a signal to noise ratio of 20 dB is obtained. The second improved version is able to detect the four multiplexed FBGs placed 250 km away, offering a signal to noise ratio of 6-8 dB. Consequently, this last system represents the longest range FBG sensor system reported so far that includes fiber sensor multiplexing capability. Both simple systems are based on a wavelength swept laser to scan the reflection spectra of the FBGs, and they are composed by two identical-lengths optical paths: the first one intended to launch the amplified laser signal by means of Raman amplification and the other one is employed to guide the reflection signal to the reception system. PMID:22164101

  2. Real Km-synthesis via generalized Popov multipliers

    NASA Technical Reports Server (NTRS)

    Chiang, R. Y.; Safonov, M. G.

    1992-01-01

    The authors refine their H-infinity control designs presented at the 1990 and 1991 American Control Conference by introducing a new real Km-synthesis technique involving the use of generalized Popov multipliers. This multiplier technique substantially reduces, and in some cases may even eliminate altogether, the conservativeness associated with traditional Km-synthesis solutions in which all uncertainties are treated as complex, even when they arise from real parameters such as the masses and spring constants in the benchmark problem. The design results demonstrate how this approach permits a very precise analysis of the intrinsic tradeoffs between robustness, performance, and control energy requirements. Also included is an open-loop H-infinity prefilter design that makes it possible to address the command response shaping issue. The design concept has been applied to the benchmark problem no. 4 and successfully removes the initial undesired transient and cuts down the percent overshoot.

  3. Kinematic characteristics of elite men's 50 km race walking.

    PubMed

    Hanley, Brian; Bissas, Athanassios; Drake, Andrew

    2013-01-01

    Race walking is an endurance event which also requires great technical ability, particularly with respect to its two distinguishing rules. The 50 km race walk is the longest event in the athletics programme at the Olympic Games. The aims of this observational study were to identify the important kinematic variables in elite men's 50 km race walking, and to measure variation in those variables at different distances. Thirty men were analysed from video data recorded during a World Race Walking Cup competition. Video data were also recorded at four distances during the European Cup Race Walking and 12 men analysed from these data. Two camcorders (50 Hz) recorded at each race for 3D analysis. The results of this study showed that walking speed was associated with both step length (r=0.54,P=0.002) and cadence (r=0.58,P=0.001). While placing the foot further ahead of the body at heel strike was associated with greater step lengths (r=0.45,P=0.013), it was also negatively associated with cadence (r= -0.62,P<0.001). In the World Cup, knee angles ranged between 175 and 186° at initial contact and between 180 and 195° at midstance. During the European Cup, walking speed decreased significantly (F=9.35,P=0.002), mostly due to a decrease in step length between 38.5 and 48.5 km (t=8.59,P=0.014). From this study, it would appear that the key areas a 50 km race walker must develop and coordinate are step length and cadence, although it is also important to ensure legal walking technique is maintained with the onset of fatigue. PMID:23679143

  4. Organizations, Paradigms, and People: The Challenge of KM Interventions

    NASA Technical Reports Server (NTRS)

    Bailey, Teresa; Burton, Yvette

    1999-01-01

    This paper presents viewgraphs on Knowledge Management (KM) and how these interventions are put into practice by organizations and society. The topics include: 1) The Multiple Paradigm Tool; 2) Four Paradigms: tool for the Analyzing Organizations; 3) Assumptions About the Nature of Social Science; 4) Assumptions About the Nature of Society; 5) Schools of Sociological and Organizational Theory; 6) Meaning and Metaphors in the Four Paradigms; and 7) Possibilities and Conclusions.

  5. The lectin KM+ induces corneal epithelial wound healing in rabbits.

    PubMed

    Chahud, Fernando; Ramalho, Leandra N Z; Ramalho, Fernando S; Haddad, Antonio; Roque-Barreira, Maria C

    2009-04-01

    Neutrophil influx is essential for corneal regeneration (Gan et al. 1999). KM+, a lectin from Artocarpus integrifolia, induces neutrophil migration (Santos-de-Oliveira et al. 1994). This study aims at investigating a possible effect of KM+ on corneal regeneration in rabbits. A 6.0-mm diameter area of debridement was created on the cornea of both eyes by mechanical scraping. The experimental eyes received drops of KM+ (2.5 microg/ml) every 2 h. The control eyes received buffer. The epithelial wounded areas of the lectin-treated and untreated eyes were stained with fluorescein, photographed and measured. The animals were killed 12 h (group 1, n = 5), 24 h (group 2, n = 10) and 48 h (group 3, n = 5) after the scraping. The corneas were analysed histologically (haematoxylin and eosin and immunostaining for proliferation cell nuclear antigen, p63, vascular endothelial growth factor, c-Met and laminin). No significant differences were found at the epithelial gap between treated and control eyes in the group 1. However, the number of neutrophils in the wounded area was significantly higher in treated eyes in this group. Three control and seven treated eyes were healed completely and only rare neutrophils persisted in the corneal stroma in group 2. No morphological distinction was observed between treated and control eyes in group 3. In treated corneas of group 2, there was an increase in immunostaining of factors involved in corneal healing compared to controls. Thus, topical application of KM+ may facilitate corneal epithelial wound healing in rabbits by means of a mechanism that involves increased influx of neutrophils into the wounded area induced by the lectin.

  6. Depressed mantle discontinuities beneath Iceland: Evidence of a garnet controlled 660 km discontinuity?

    NASA Astrophysics Data System (ADS)

    Jenkins, J.; Cottaar, S.; White, R. S.; Deuss, A.

    2016-01-01

    The presence of a mantle plume beneath Iceland has long been hypothesised to explain its high volumes of crustal volcanism. Practical constraints in seismic tomography mean that thin, slow velocity anomalies representative of a mantle plume signature are difficult to image. However it is possible to infer the presence of temperature anomalies at depth from the effect they have on phase transitions in surrounding mantle material. Phase changes in the olivine component of mantle rocks are thought to be responsible for global mantle seismic discontinuities at 410 and 660 km depth, though exact depths are dependent on surrounding temperature conditions. This study uses P to S seismic wave conversions at mantle discontinuities to investigate variation in topography allowing inference of temperature anomalies within the transition zone. We employ a large data set from a wide range of seismic stations across the North Atlantic region and a dense network in Iceland, including over 100 stations run by the University of Cambridge. Data are used to create over 6000 receiver functions. These are converted from time to depth including 3D corrections for variations in crustal thickness and upper mantle velocity heterogeneities, and then stacked based on common conversion points. We find that both the 410 and 660 km discontinuities are depressed under Iceland compared to normal depths in the surrounding region. The depression of 30 km observed on the 410 km discontinuity could be artificially deepened by un-modelled slow anomalies in the correcting velocity model. Adding a slow velocity conduit of -1.44% reduces the depression to 18 km; in this scenario both the velocity reduction and discontinuity topography reflect a temperature anomaly of 210 K. We find that much larger velocity reductions would be required to remove all depression on the 660 km discontinuity, and therefore correlated discontinuity depressions appear to be a robust feature of the data. While it is not possible

  7. Acceleration of barium ions near 8000 km above an aurora

    NASA Technical Reports Server (NTRS)

    Stenbaek-Nielsen, H. C.; Hallinan, T. J.; Wescott, E. M.; Foeppl, H.

    1984-01-01

    A barium shaped charge, named Limerick, was released from a rocket launched from Poker Flat Research Range, Alaska, on March 30, 1982, at 1033 UT. The release took place in a small auroral breakup. The jet of ionized barium reached an altitude of 8100 km 14.5 min after release, indicating that there were no parallel electric fields below this altitude. At 8100 km the jet appeared to stop. Analysis shows that the barium at this altitude was effectively removed from the tip. It is concluded that the barium was actually accelerated upward, resulting in a large decrease in the line-of-sight density and hence the optical intensity. The parallel electric potential in the acceleration region must have been greater than 1 kV over an altitude interval of less than 200 km. The acceleration region, although presumably auroral in origin, did not seem to be related to individual auroral structures, but appeared to be a large-scale horizontal structure. The perpendicular electric field below, as deduced from the drift of the barium, was temporally and spatially very uniform and showed no variation related to individual auroral structures passing through.

  8. The influence of performance level, age and gender on pacing strategy during a 100-km ultramarathon.

    PubMed

    Renfree, Andrew; Crivoi do Carmo, Everton; Martin, Louise

    2016-01-01

    The aim of this study is to analyse the influence of performance level, age and gender on pacing during a 100-km ultramarathon. Results of a 100-km race incorporating the World Masters Championships were used to identify differences in relative speeds in each 10-km segment between participants finishing in the first, second, third and fourth quartiles of overall positions (Groups 1, 2, 3 and 4, respectively). Similar analyses were performed between the top and bottom 50% of finishers in each age category, as well as within male and female categories. Pacing varied between athletes achieving different absolute performance levels. Group 1 ran at significantly lower relative speeds than all other groups in the first three 10-km segments (all P < 0.01), and significantly higher relative speeds than Group 4 in the 6th and 10th (both P < 0.01), and Group 2 in the 8th (P = 0.04). Group 4 displayed significantly higher relative speeds than Group 2 and 3 in the first three segments (all P < 0.01). Overall strategies remained consistent across age categories, although a similar phenomenon was observed within each category whereby 'top' competitors displayed lower relative speeds than 'bottom' competitors in the early stages, but higher relative speeds in the later stages. Females showed lower relative starting speeds and higher finishing speeds than males. 'Top' and 'bottom' finishing males displayed differing strategies, but this was not the case within females. Although pacing remained consistent across age categories, it differed with level of performance within each, possibly suggesting strategies are anchored on direct competitors. Strategy differs between genders and differs depending on performance level achieved in males but not females. PMID:26034882

  9. Ad-libitum drinking and performance during a 40-km cycling time trial in the heat.

    PubMed

    Berkulo, Meriam A R; Bol, Susan; Levels, Koen; Lamberts, Robert P; Daanen, Hein A M; Noakes, Timothy D

    2016-01-01

    The aim of this study was to investigate if drinking ad-libitum can counteract potential negative effects of a hypohydrated start caused by fluid restriction during a 40-km time trial (TT) in the heat. Twelve trained males performed one 40-km cycling TT euhydrated (EU: no water during the TT) and two 40-km cycling TTs hypohydrated. During one hypohydrated trial no fluid was ingested (HYPO), during the other trial ad-libitum water ingestion was allowed (FLUID). Ambient temperature was 35.2 ± 0.2 °C, relative humidity 51 ± 3% and airflow 7 m·s(-1). Body mass (BM) was determined at the start of the test, and before and after the TT. During the TT, power output, heart rate (HR), gastrointestinal temperature, mean skin temperature, rating of perceived exertion (RPE), thermal sensation, thermal comfort and thirst sensation were measured. Prior to the start of the TT, BM was 1.2% lower in HYPO and FLUID compared to EU. During the TT, BM loss in FLUID was lower compared to EU and HYPO (1.0 ± 0.8%, 2.7 ± 0.2% and 2.6 ± 0.3%, respectively). Hydration status had no effect on power output (EU: 223 ± 32 W, HYPO: 217 ± 39 W, FLUID: 224 ± 35 W), HR, gastrointestinal temperature, mean skin temperature, RPE, thermal sensation and thermal comfort. Thirst sensation was higher in HYPO than in EU and FLUID. It was concluded that hypohydration did not adversely affect performance during a 40-km cycling TT in the heat. Therefore, whether or not participants consumed fluid during exercise did not influence their TT performance.

  10. Demonstration of Femtosecond-Phase Stabilization in 2 km OpticalFiber

    SciTech Connect

    Staples, J.W.; Wilcox, R.; Byrd, J.M.

    2007-06-01

    Long-term phase drifts of less than a femtosecond per hour have been demonstrated in a 2 km length of single-mode optical fiber, stabilized interferometrically at 1530 nm. Recent improvements include a wide-band phase detector that reduces the possibility of fringe jumping due to fast external perturbations of the fiber and locking of the master CW laser wavelength to an atomic absorption line. Mode-locked lasers may be synchronized using two wavelengths of the comb, multiplexed over one fiber, each wavelength individually interferometrically stabilized.

  11. 1,2,4,5-Tetrachlorobenzene

    Integrated Risk Information System (IRIS)

    1,2,4,5 - Tetrachlorobenzene ; CASRN 95 - 94 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Nonca

  12. 1,1,1,2-Tetrafluoroethane

    Integrated Risk Information System (IRIS)

    1,1,1,2 - Tetrafluoroethane ; CASRN 811 - 97 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Nonca

  13. 1,1,2,2-Tetrachloroethane

    Integrated Risk Information System (IRIS)

    1,1,2,2 - Tetrachloroethane ; CASRN 79 - 34 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncar

  14. 1,2-Dibromo-3-chloropropane (DBCP)

    Integrated Risk Information System (IRIS)

    1,2 - Dibromo - 3 - chloropropane ( DBCP ) ; CASRN 96 - 12 - 8 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessm

  15. 1,1,1,2-Tetrachloroethane

    Integrated Risk Information System (IRIS)

    1,1,1,2 - Tetrachloroethane ; CASRN 630 - 20 - 6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Nonca

  16. 1,2,3-triazolium ionic liquids

    DOEpatents

    Luebke, David; Nulwala, Hunaid; Tang, Chau

    2014-12-09

    The present invention relates to compositions of matter that are ionic liquids, the compositions comprising substituted 1,2,3-triazolium cations combined with any anion. Compositions of the invention should be useful in the separation of gases and, perhaps, as catalysts for many reactions.

  17. 43 CFR 1815.1-2 - Applications.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF THE INTERIOR GENERAL MANAGEMENT (1000) INTRODUCTION AND GENERAL GUIDANCE Disaster Relief § 1815.1-2 Applications. (a) Place of filing. The application for relief shall be filed in the office which... particular disaster and its effect upon contract performance. (3) An estimate of the damages suffered. (4)...

  18. Internal rotation for predicting conformational population of 1,2-difluorethane and 1,2-dichloroethane

    NASA Astrophysics Data System (ADS)

    Venâncio, Mateus F.; Dos Santos, Hélio F.; De Almeida, Wagner B.

    2016-06-01

    The contribution of internal rotation to the thermal correction of Gibbs free energy (ΔG) is estimated using the quantum pendulum model (QPM) to solve the characteristic Schrödinger equation. The procedure is applied to theoretical prediction of conformational population of 1,2-difluorethane (1,2-DFE) and 1,2-dichloroethane (1,2-DCE) molecules. The predicted population for the anti form was 37% and 75%, for 1,2-DFE and 1,2-DCE respectively, in excellent agreement with experimental gas phase data available, 37 ± 5% and 78 ± 5%. These results provide great support to the use of the QPM model to account for the low vibrational frequency modes effect on the calculation of thermodynamic properties.

  19. Comparison of broadband mode arrivals at ranges of 3515 km and 5171 km in the North Pacific

    NASA Astrophysics Data System (ADS)

    Wage, Kathleen E.

    2003-04-01

    The Acoustic Thermometry of Ocean Climate (ATOC) provided an opportunity to observe signals propagating in the low-order modes of the ocean waveguide. Understanding the fluctuations of these mode signals is an important prerequisite to using them for tomography or other applications. In previous work, we characterized the cross-mode coherence and temporal variability of the low-order mode arrivals at 3515 km range [Wage et al., J. Acoust. Soc. Am. (in press)]. This study compares the mode arrivals for two different ranges : 3515 km and 5171 km, using data from the ATOC vertical line arrays at Hawaii and Kiritimati. We discuss the mode intensity and coherence statistics for each of the arrays and examine mean arrival time trends over the year-long deployment. Experimental results are compared to PE simulations of propagation through a realistic background environment perturbed by internal waves of varying strengths. The dependence of mode statistics on the path-dependent changes in the background sound speed and the parameters of the internal wave field is explored. [Work supported by an ONR Ocean Acoustics Young Faculty Award.] a)A. B. Baggeroer, T. G. Birdsall, C. Clark, J. A. Colosi, B. D. Cornuelle, D. Costa, B. D. Dushaw, M. A. Dzieciuch, A. M. G. Forbes, B. M. Howe, D. Menemenlis, J. A. Mercer, K. Metzger, W. H. Munk, R. C. Spindel, P. F. Worcester, and C. Wunsch.

  20. Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions.

    PubMed

    Kawata, Yoshikazu; Nishimura, Taku; Matsushita, Isao; Tsubota, Jun

    2016-03-01

    The alkaliphilic, halophilic bacterium Halomonas sp. KM-1 can utilize both hexose and pentose sugars for the intracellular storage of bioplastic poly-(R)-3-hydroxybutyric acid (PHB) under aerobic conditions. In this study, we investigated the effects of the sodium nitrate concentration on PHB accumulation in the KM-1 strain. Unexpectedly, we observed the secretion of pyruvate, a central intermediate in carbon- and energy-metabolism processes in all organisms; therefore, pyruvate is widely used as a starting material in the industrial biosynthesis of pharmaceuticals and is employed for the production of crop-protection agents, polymers, cosmetics, and food additives. We then further analyzed pyruvate productivity following changes in culture temperature and the buffer concentration. In 48-h batch-cultivation experiments, we found that wild-type Halomonas sp. KM-1 secreted 63.3 g/L pyruvate at a rate of 1.32 g/(L·h), comparable to the results of former studies using mutant and recombinant microorganisms. Thus, these data provided important insights into the production of pyruvate using this novel strain.

  1. Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions.

    PubMed

    Kawata, Yoshikazu; Nishimura, Taku; Matsushita, Isao; Tsubota, Jun

    2016-03-01

    The alkaliphilic, halophilic bacterium Halomonas sp. KM-1 can utilize both hexose and pentose sugars for the intracellular storage of bioplastic poly-(R)-3-hydroxybutyric acid (PHB) under aerobic conditions. In this study, we investigated the effects of the sodium nitrate concentration on PHB accumulation in the KM-1 strain. Unexpectedly, we observed the secretion of pyruvate, a central intermediate in carbon- and energy-metabolism processes in all organisms; therefore, pyruvate is widely used as a starting material in the industrial biosynthesis of pharmaceuticals and is employed for the production of crop-protection agents, polymers, cosmetics, and food additives. We then further analyzed pyruvate productivity following changes in culture temperature and the buffer concentration. In 48-h batch-cultivation experiments, we found that wild-type Halomonas sp. KM-1 secreted 63.3 g/L pyruvate at a rate of 1.32 g/(L·h), comparable to the results of former studies using mutant and recombinant microorganisms. Thus, these data provided important insights into the production of pyruvate using this novel strain. PMID:26989057

  2. Will women outrun men in ultra-marathon road races from 50 km to 1,000 km?

    PubMed

    Zingg, Matthias Alexander; Karner-Rezek, Klaus; Rosemann, Thomas; Knechtle, Beat; Lepers, Romuald; Rüst, Christoph Alexander

    2014-01-01

    It has been assumed that women would be able to outrun men in ultra-marathon running. The present study investigated the sex differences in running speed in ultra-marathons held worldwide from 50 km to 1,000 km. Changes in running speeds and the sex differences in running speeds in the annual fastest finishers in 50 km, 100 km, 200 km and 1,000 km events held worldwide from 1969-2012 were analysed using linear, non-linear and multi-level regression analyses. For the annual fastest and the annual ten fastest finishers, running speeds increased non-linearly in 50 km and 100 km, but not in 200 km and 1,000 km where running speeds remained unchanged for the annual fastest. The sex differences decreased non-linearly in 50 km and 100 km, but not in 200 and 1,000 km where the sex difference remained unchanged for the annual fastest. For the fastest women and men ever, the sex difference in running speed was lowest in 100 km (5.0%) and highest in 50 km (15.4%). For the ten fastest women and men ever, the sex difference was lowest in 100 km (10.0 ± 3.0%) and highest in 200 km (27.3 ± 5.7%). For both the fastest (r(2) = 0.003, p = 0.82) and the ten fastest finishers ever (r(2) = 0.34, p = 0.41) in 50 km, 100 km, 200 km and 1,000 km, we found no correlation between sex difference in performance and running speed. To summarize, the sex differences in running speeds decreased non-linearly in 50 km and 100 km but remained unchanged in 200 km and 1,000 km, and the sex differences in running speeds showed no change with increasing length of the race distance. These findings suggest that it is very unlikely that women will ever outrun men in ultra-marathons held from 50 km to 100 km.

  3. fine structure of 410km discontinuity beneath the Southern Europe

    NASA Astrophysics Data System (ADS)

    Wan, K.; Wan, X.; Ni, S.

    2005-12-01

    In the distance range of 10-14 degrees, P waves from the topside reflection off the 410km discontinuity are very sensitive to the fine structure of the discontinuity. We analyzed 49 broadband seismograms from an earthquake ( May 18, 1998) in Italy (Mw 5.8) , recorded by Orfeus and SZGRF networks. Distances between the source and the stations were from 9° to 19°, and provided a detailed look at the 410km structure. On the other hand, the azimuth of these records were in a narrow range from 334° and 356°, so the differences in azimuth may have little effects on the waveforms. From our observation, P410 phase has little change in amplitude when the distance decreases from 15° to about 11.5°. However, an abrupt termination was observed from distance 11° to 10.5°. These features cannot be explained with PREM model. We calculated several groups of models with F-K method and compared their synthetic seismograms with the observed one. These models are: 1) two-step sharp jump models, with different thickness; 2) linear models; 3) linear-sharp jump models[Tim Melbourne, Don Helmberger, Journal of Geophysical Research, 1998]; 4) models calculated from a mineralogical model[Gaherty, Wang, Geophysical research letters, 1999]; Features in the observed waveform can be well modeled with model 3 and 4 while only parts of them fitted to model 1 or 2. But when we calculated with a less detailed model, seismograms of model 4 should have more noise than model 3. In conclusion, the structure of 410km discontinuity can be considered as a linear-sharp velocity jump, which is consistent with mineralogical models.

  4. Mapping the global land surface using 1 km AVHRR data

    USGS Publications Warehouse

    Lauer, D.T.; Eidenshink, J.C.

    1998-01-01

    The scientific requirements for mapping the global land surface using 1 km advanced very high resolution radiometer (AVHRR) data have been set forth by the U.S. Global Change Research Program; the International Geosphere Biosphere Programme (IGBP); The United Nations; the National Oceanic and Atmospheric Administration (NOAA); the Committee on Earth Observations Satellites; and the National Aeronautics and Space Administration (NASA) mission to planet Earth (MTPE) program. Mapping the global land surface using 1 km AVHRR data is an international effort to acquire, archive, process, and distribute 1 km AVHRR data to meet the needs of the international science community. A network of AVHRR receiving stations, along with data recorded by NOAA, has been acquiring daily global land coverage since April 1, 1992. A data set of over 70,000 AVHRR images is archived and distributed by the United States Geological Survey (USGS) EROS Data Center, and the European Space Agency. Under the guidance of the IGBP, processing standards have been developed for calibration, atmospheric correction, geometric registration, and the production of global 10-day maximum normalized difference vegetation index (NDVI) composites. The major uses of the composites are for the study of surface vegetation condition, mapping land cover, and deriving biophysical characteristics of terrestrial ecosystems. A time-series of 54 10-day global vegetation index composites for the period of April 1, 1992 through September 1993 has been produced. The production of a time-series of 33 10-day global vegetation index composites using NOAA-14 data for the period of February 1, 1995 through December 31, 1995 is underway. The data products are available from the USGS, in cooperation with NASA's MTPE program and other international organizations.

  5. 157km BOTDA with pulse coding and image processing

    NASA Astrophysics Data System (ADS)

    Qian, Xianyang; Wang, Zinan; Wang, Song; Xue, Naitian; Sun, Wei; Zhang, Li; Zhang, Bin; Rao, Yunjiang

    2016-05-01

    A repeater-less Brillouin optical time-domain analyzer (BOTDA) with 157.68km sensing range is demonstrated, using the combination of random fiber laser Raman pumping and low-noise laser-diode-Raman pumping. With optical pulse coding (OPC) and Non Local Means (NLM) image processing, temperature sensing with +/-0.70°C uncertainty and 8m spatial resolution is experimentally demonstrated. The image processing approach has been proved to be compatible with OPC, and it further increases the figure-of-merit (FoM) of the system by 57%.

  6. The relational database system of KM3NeT

    NASA Astrophysics Data System (ADS)

    Albert, Arnauld; Bozza, Cristiano

    2016-04-01

    The KM3NeT Collaboration is building a new generation of neutrino telescopes in the Mediterranean Sea. For these telescopes, a relational database is designed and implemented for several purposes, such as the centralised management of accounts, the storage of all documentation about components and the status of the detector and information about slow control and calibration data. It also contains information useful during the construction and the data acquisition phases. Highlights in the database schema, storage and management are discussed along with design choices that have impact on performances. In most cases, the database is not accessed directly by applications, but via a custom designed Web application server.

  7. An evaluation of the global 1-km AVHRR land dataset

    USGS Publications Warehouse

    Teillet, P.M.; El Saleous, N.; Hansen, M.C.; Eidenshink, Jeffery C.; Justice, C.O.; Townshend, J.R.G.

    2000-01-01

    This paper summarizes the steps taken in the generation of the global 1-km AVHRR land dataset, and it documents an evaluation of the data product with respect to the original specifications and its usefulness in research and applications to date. The evaluation addresses data characterization, processing, compositing and handling issues. Examples of the main scientific outputs are presented and options for improved processing are outlined and prioritized. The dataset has made a significant contribution, and a strong recommendation is made for its reprocessing and continuation to produce a long-term record for global change research.

  8. 1,2-Diazinium hydrogen chloranilate

    PubMed Central

    Gotoh, Kazuma; Ishida, Hiroyuki

    2008-01-01

    In the crystal structure of the title compound, C4H5N2 +·C6HCl2O4 −, there are three crystallographically independent 1,2-diazinium cations and hydrogen chloranilate anions. The anions are held together by pairs of O—H⋯O hydrogen bonds to form two types of dimers, one of which is centrosymmetric. The 1,2-diazinium cations are linked on both sides of each dimer via bifurcated N—H⋯O hydrogen bonds to give two kinds of 2–2 cation–anion associations. The 2–2 associations are linked by inter­molecular C—H⋯O and C—H⋯N hydrogen bonds, forming a mol­ecular tape along the [230] direction. The tapes are further connected by C—H⋯O hydrogen bonds, forming a three-dimensional network. PMID:21580959

  9. Nitrone Cycloadditions of 1,2-Cyclohexadiene

    PubMed Central

    Barber, Joyann S.; Styduhar, Evan D.; Pham, Hung V.; McMahon, Travis C.; Houk, K. N.; Garg, Neil K.

    2016-01-01

    We report the first 1,3-dipolar cycloadditions of 1,2-cyclohexadiene, a rarely exploited strained allene. 1,2-Cyclohexadiene is generated in situ under mild conditions and trapped with nitrones to give isoxazolidine products in synthetically useful yields. The reactions occur regioselectively and exhibit a notable endo preference, thus resulting in the controlled formation of two new bonds and two stereogenic centers. DFT calculations of stepwise and concerted reaction pathways are used to rationalize the observed selectivities. Moreover, the strategic manipulation of nitrone cycloadducts demonstrates the utility of this methodology for the assembly of compounds bearing multiple heterocyclic units. These studies showcase the exploitation of a traditionally avoided reactive intermediate in chemical synthesis. PMID:26854652

  10. Survival of Nannochloropsis Phytoplankton in Hypervelocity Impact Events up to Velocities of 6.07 km/s

    NASA Astrophysics Data System (ADS)

    Pasini, D. L. S.; Price, M. C.; Burchell, M. J.; Cole, M. J.

    2013-09-01

    Studies have previously been conducted to verify the survivability of living cells during hypervelocity impact events to test the panspermia and lithopanspermia hypothesis [1], [2]. It has been demonstrated that bacteria survive impacts up to 5.4 km s-1 (approx. shock pressure 30 GPa) - albeit with a low probability of survival [1] whilst larger more complex objects (such as seeds) break up at ~1 km s-1 [2]. The survivability of yeast spores in impacts up to 7.4 km s-1 has also recently been shown [3]. We demonstrate here the survivability of Nannochloropsis Phytoplankton, a eukaryotic photosynthesizing autotroph found in the 'euphotic zone'(sunlit surface layers of oceans) [4] at impact velocities up to 6.07 km s-1. Phytoplankton from a culture sample was frozen and then fired into water (to simulate oceanic impacts, as described in [5]) using a light gas gun (LGG) [6]. The water was then retrieved and placed into a sealed culture vessel and left under a constant light source to check the viability of any remnant organisms.

  11. Quantum crytography over 14km of installed optical fiber

    SciTech Connect

    Hughes, R.J.; Luther, G.G.; Morgan, G.L.; Simmons, C.

    1995-09-01

    We have made the first demonstration that low error rate quantum cryptography over long distances (14km) of installed optical fiber in a real-world environment, subject to uncontrolled temperature and mechanical influences, representing an important new step towards incorporation of quantum cryptography into existing information security systems. We also point out that the high visibility single-photon interference in our experiment allows us to infer a test of the superposition principle of quantum mechanics: a photon reaching the detector has traveled over 14km of optical fiber in a wavepacket comprising a coherent superposition of two components that are spatially separated by about 2m. In principle, there are decoherence processes (or even possible modifications of quantum mechanics) that could cause the photon`s wavefunction to collapse into one component or the other during propagation, leading to a reduction in visibility. However, our results are consistent with no such loss of quantum coherence during the 67-{mu}s propagation time.

  12. Infrared emission from the atmosphere above 200 km

    NASA Technical Reports Server (NTRS)

    Simpson, J. P.

    1976-01-01

    The infrared radiation over the range from 4 to 1000 microns from atoms and molecules in the earth's atmosphere, between 200 and 400 km, was calculated. Only zenith lines of sight were considered. The excitation of the atoms and molecules is due to collisions with other molecules and to absorption of radiation from the earth and sun. In some cases, the abundances of the molecules had to be estimated. The most important lines are the forbidden lines from atomic oxygen at 63.1 and 147 micron, and the vibration-rotation band of nitric oxide at 5.3 micron. These lines can have intensities as high as a few times 0.001 ergs/sq cm/sec/steradian at 200 km altitude. In addition, the vibration-rotation bands of NO(+) at 4.3 micron and CO at 4.7 micron and the pure rotation lines of NO and NO(+) could be detected by infrared telescopes in space.

  13. KM3NeT/ORCA status and plans

    NASA Astrophysics Data System (ADS)

    Samtleben, Dorothea F. E.

    2016-04-01

    Neutrinos created in interactions of cosmic rays with the atmosphere can serve as a powerful tool to unveil the neutrino mass hierarchy (NMH). At low energies, around a few GeV, matter effects from the transition through the Earth are expected to imprint a distinct but also subtle signature on the oscillation pattern, specific to the ordering of the neutrino masses. KM3NeT/ORCA (Oscillations Research with Cosmics in the Abyss), a densely instrumented building block of the upcoming KM3NeT neutrino telescope, will be designated to measuring this signature in the Mediterranean Sea. Using detailed simulations the sensitivity towards this signature has been evaluated. The multi-PMT detectors allow in the water for an accurate reconstruction of GeV neutrino event signatures and distinction of neutrino flavours. For the determination of the mass hierarchy a median significance of 2-6σ has been estimated for three years of data taking, depending on the actual hierarchy and the oscillation parameters. At the same time the values of several oscillation parameters like θ23 will be determined to unprecedented precision.

  14. 1,1,2-Trichloro-1,2,2-trifluoroethane (CFC-113)

    Integrated Risk Information System (IRIS)

    1,1,2 - Trichloro - 1,2,2 - trifluoroethane ( CFC - 113 ) ; CASRN 76 - 13 - 1 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health

  15. Equilibria of 1,1,2,-trichloro-1,2,2-trifluoroethane on activated carbons

    SciTech Connect

    Cho, S.Y.; Lee, Y.Y.

    1995-07-01

    ChloroFluoroCarbons (CFCs) are now considered to be the prime contribution to stratospheric ozone depletion. As a result, the use of activated carbons to adsorb specific CFCs has received great attention. In this paper, the equilibrium adsorption characteristics of 1,1,2-trichloro-1,2,2-trifluoroethane vapor on different-shaped carbons were studied. Adsorption isotherms of 1,2,2-trichloro-1,2,2-trifluoroethane on an activated carbon pellet and an activated carbon felt were measured. The equilibria of 1,1,2-trichloro-1,2,2-trifluoroethane on the activated carbon pellet having a dual pore structure were expressed by the Redlich-Peterson equation, and equilibrium constants were expressed as functions of temperature from 298 to 393 K. On the other hand, the equilibria of 1,1,2-trichloro-1,2,2-trifluoroethane on the activated carbon felt having a relatively uniform pore structure were interpreted by the Dubinin-Radushkevich correlation based on the micropore volume filling theory. The affinity coefficient was correlated by the molar polarization.

  16. Castro ring zone: a 4,500-km2 fossil hydrothermal system in the Challis volcanic field, central Idaho.

    USGS Publications Warehouse

    Criss, R.E.; Ekren, E.B.; Hardyman, R.F.

    1984-01-01

    The largest fossil hydrothermal system occupying a 4500 km2 area in central Idaho is revealed by delta 18O studies. The remains of this meteoric-hydrothermal system are preserved within a sharply bounded, 15 km wide, 70-km-diameter annulus of low delta 18O rock (+2.0 to -8.8per mille) termed the Castro ring zone. The zone is centred on a less depleted (+4.5) core zone consisting of granitic rocks of the Castro pluton. This 700-km2 Eocene subvolcanic batholith has intruded, domed, and hydrothermally metamorphosed a thick sequence of Challis Volcanics, the stratigraphically low rocks in the 2000-km2 Van Horn Peak and the 1000-km2 Thunder Mountain cauldron complexes being most strongly altered. Less extreme 18O depletions occur in the youngest major ash-flow sheets of these complexes, indicating a vertical 18O gradient. Water/rock ratios of geothermal systems are surprisingly insensitive to the circulation scale.-L.-di H.

  17. Hybrid fine scale climatology and microphysics of in-cloud icing: From 32 km reanalysis to 5 km mesoscale modeling

    NASA Astrophysics Data System (ADS)

    Lamraoui, Fayçal; Benoit, Robert; Perron, Jean; Fortin, Guy; Masson, Christian

    2015-03-01

    In-cloud icing can impose safety concerns and economic challenges for various industries. Icing climate representations proved beneficial for optimal designs and careful planning. The current study investigates in-cloud icing, its related cloud microphysics and introduces a 15-year time period climatology of icing events. The model was initially driven by reanalysis data from North American Regional Reanalysis and downscaled through a two-level nesting of 10 km and 5 km, using a limited-area version of the Global Environment Multiscale Model of the Canadian Meteorological Center. In addition, a hybrid approach is used to reduce time consuming calculations. The simulation realized exclusively on significant icing days, was combined with non-significant icing days as represented by data from NARR. A proof of concept is presented here for a 1000 km area around Gaspé during January for those 15 years. An increase in the number and intensity of icing events has been identified during the last 15 years. From GEM-LAM simulations and within the atmospheric layer between 10 m and 200 m AGL, supercooled liquid water contents indicated a maximum of 0.4 g m- 3, and 50% of the values are less than 0.05 g m- 3. All values of median volume diameters (MVD) are approximately capped by 70 μm and the typical values are around 15 μm. Supercooled Large Droplets represent approximately 5%. The vertical profile of icing climatology demonstrates a steady duration of icing events until the level of 60 m. The altitudes of 60 m and 100 m indicate substantial icing intensification toward higher elevations. GEM-LAM demonstrated a substantial improvement in the calculation of in-cloud icing, reducing significantly the challenge posed by complex terrains.

  18. Measurements of laser phase fluctuations induced by atmospheric turbulence over 2 km and 17.5 km distances.

    PubMed

    Ridley, Kevin D

    2011-09-10

    A laser heterodyne system was used to measure the phase fluctuations imposed on a 1.5 μm wavelength laser beam when double-passed over long atmospheric paths. Two distances were used: 2 and 17.5 km. Results are given for intensity scintillation, phase fluctuation time series and spectra, and phase structure function. The results are found to agree well with theory: the spectrum of phase fluctuations follows the 8/3 power law predicted for Kolmogorov turbulence over 3 orders of magnitude in frequency. The methods reported here could be used to investigate large-scale temperature variations in the atmosphere. PMID:21946989

  19. (1+2)-dimensional strongly nonlocal solitons

    SciTech Connect

    Ouyang Shigen; Guo Qi

    2007-11-15

    Approximate solutions of (1+2)-dimensional strongly nonlocal solitons (SNSs) are presented. It is shown that the power of a SNS in a nematic liquid crystal is in direct proportion to the second power of the degree of nonlocality, the power of a SNS in a nonlocal medium with a logarithmic nonlocal response is in inverse proportion to the second power of its beamwidth, and the power of a SNS in a nonlocal medium with an sth-power decay nonlocal response is in direct proportion to the (s+2)th power of the degree of nonlocality.

  20. Modes of zonal mean temperature variability 20-100 km from the TIMED/SABER observations

    NASA Astrophysics Data System (ADS)

    Jiang, Y.; Sheng, Z.; Shi, H. Q.

    2014-03-01

    In this study we investigate the spatial variabilities of the zonal mean temperature (20-100 km) from the TIMED (Thermosphere, Ionosphere, Mesosphere, Energetics and Dynamics)/SABER (Sounding of the Atmosphere using Broadband Emission Radiometry) satellite using the empirical orthogonal functions (EOFs). After removing the climatological annual mean, the first three EOFs are able to explain 87.0% of temperature variabilities. The primary EOF represents 74.1% of total anomalies and is dominated by the north-south contrast. Patterns in the second and third EOFs are related to the semiannual oscillations (SAO) and mesospheric temperature inversions (MTI), respectively. The quasi-biennial oscillation (QBO) component is also decomposed into the seventh EOF with contributions of 1.2%. Last, we use the first three modes and annual mean temperature to reconstruct the data. The result shows small differences are in low latitude, which increase with latitude in the middle stratosphere and upper mesosphere.

  1. Biological and Abiotic Transformations of Ethylene Dibromide and 1,2-Dichloroethane in Ground Water at Leaded Gasoline Spill Sites

    EPA Science Inventory

    Tetra-ethyl lead was widely used in leaded automobile gasoline from 1923 until 1987. To prevent lead deposits from fouling the engine, 1,2-dibromoethane (EDB) and 1,2-dichloroethane (1,2-DCA) were added to the gasoline to act as lead scavengers. The Maximum Contaminant Levels...

  2. The ion population between 1300 km and 230000 km in the coma of comet P/Halley

    NASA Technical Reports Server (NTRS)

    Altwegg, K.; Balsiger, H.; Geiss, J.; Goldstein, R.; Ip, W. -H.; Meier, A.; Neugebauer, M.; Rosenbauer, H.; Shelley, E.

    1993-01-01

    During the encounter of the spacecraft Giotto with Comet Halley the two sensors of the ion mass spectrometer (IMS), high energy range spectrometer (HERS) and high intensity spectrometer (HIS), measured the mass and the three-dimensional velocity distributions of cometary ions. HIS looked mainly at the cold, slow part of the distribution close to the nucleus, HERS at the more energetic pick-up ions further out. After a thorough recalibration of the HIS flight spare unit and an extensive data analysis we present here continuous ion density-, composition-, velocity-, and temperature profiles for the water group ion (mass range 16-19 amu/e) along Giotto's inbound trajectory from 230,000 to 1300 km from the comet nucleus. The two sensors are in very good agreement in the region where their measurements overlap thus giving an excellent data base for the discussion of theoretical comet models. The most prominent feature where models and observations disagree is the so called pile up region between 8000 and 15,000 km from the nucleus.

  3. Wintertime density perturbations near 50 km in relation to latitude

    NASA Technical Reports Server (NTRS)

    Quiroz, R. S.

    1977-01-01

    Standard and reference atmospheres which depict the horizontal distribution of air density in the stratosphere and mesosphere are not realistic in that they do not provide information on the large departures from standard that may occur during a given month, nor on the time- and space-scales of atmospheric perturbations responsible for these departures. In the present paper, it is shown how this information can be obtained from a special analysis of satellite radiance measurements. Plots of the mean zonal radiance, obtained with the VTPR instrument, and the corresponding 50-km density show not only the expected strong poleward gradient of density, but also a strong density surge from late December to early January, affecting all latitudes.

  4. Transport System for Delivery Tourists At Altitude 140 km

    NASA Technical Reports Server (NTRS)

    Bolonkin, Alexander

    2002-01-01

    The author offers a new method and installation for flight in space. This method uses the centrifugal force of a rotating circular cable that provides a means for the launch of a payload into outer space, to keep the fixed space stations at high altitudes (up to 200 km). The method may also be useful for landing to space bodies, for launching of the space ships (crafts), and for moving and accelerating other artificial apparatuses. The offered installation may be used as a propulsion system for space ships and/or probes. This system uses the material of any space body (i.e. stones) for acceleration and change of the space vehicle trajectory. The suggested system may be also used as a high capacity energy accumulator.

  5. Estimating worldwide solar radiation resources on a 40km grid

    SciTech Connect

    Maxwell, E.L.; George, R.L.; Brady, E.H.

    1996-11-01

    During 1995, the National Renewable Energy Laboratory (NREL), initiated the Data Grid Task under the auspices of DOE`s Resource Assessment Program. A data grid is a framework of uniformly spaced locations (grid points) for which data are available. Estimates of monthly averages of direct normal, diffuse horizontal, and global horizontal daily-total solar radiation energy (kWh/m{sup 2}) are being made for each point on a grid covering the US, Mexico, the Caribbean, and southern Canada. The grid points are separated by approximately 40 km. Using interpolation methods, the digital data grid can be used to estimate solar resources at any location. The most encouraging result to date has been the location of sources providing worldwide data for most of the input parameters required for modeling daily total solar radiation. This is a multiyear task expected to continue through the rest of this century.

  6. Readout and data acquisition for KM3NeT

    NASA Astrophysics Data System (ADS)

    Belias, Anastasios; Manolopoulos, Konstantinos

    2013-05-01

    In the KM3NeT neutrino telescope design the readout concept is based on a point-to-point network connecting tenthousands of optical modules in the deep sea through a photonic network with the shore station. The time-over-threshold data from each Photo Multiplier Tube (PMT) of each optical module will be send to shore over fibres using dedicated wavelengths. Nanosecond timing accuracy will be schieved using a clock signal embedded in the data stream and measuring the roundtrip time from the shore to each optical module individually. The DAQ software architecture based on the Internet Communications Engine (ICE) will provide a common and uniform software framework for the control of each optical module and the data acquisition of the whole neutrino telescope.

  7. Changes in single skinfold thickness in 100 km ultramarathoners

    PubMed Central

    Knechtle, Beat; Baumgartner, Sabrina; Knechtle, Patrizia; Rüst, Christoph Alexander; Rosemann, Thomas; Bescós, Raúl

    2012-01-01

    Background Changes in single skinfold thickness and body fat have been investigated in ultraswimmers and ultracyclists, but not in ultrarunners. The present study investigated the changes in single skinfold thickness during a 100 km ultramarathon. Methods Firstly, we investigated associations between prerace preparation and prerace body composition and, secondly, changes in single skinfold thickness during a 100 km ultramarathon in 219 male ultramarathoners. Changes in fat mass and skeletal muscle were estimated using anthropometric methods. Results Kilometers run weekly prerace and running speed during training were negatively associated with all skinfold thicknesses (P < 0.05) except for the front thigh skinfold. During the race, skinfold thickness at the pectoral (−0.1%), suprailiac (−1.8%), and calf (−0.8%) sites decreased (P < 0.05). The subjects lost 1.9 ± 1.4 kg of body mass (P < 0.001), 0.7 ± 1.0 kg of estimated skeletal muscle mass (P < 0.001), and 0.2 ± 1.3 kg of estimated fat mass (P < 0.05). The decrease in body mass was positively related to the decrease in both estimated skeletal muscle mass (r = 0.21, P = 0.0017) and estimated fat mass (r = 0.41, P < 0.0001). Conclusion Firstly, prerace fat mass and prerace skinfold thickness were associated with both volume and speed in running training. Secondly, during the ultramarathon, skinfold thickness decreased at the pectoral, suprailiac, and calf sites, but not at the thigh site. Percent decreases in skinfold thickness for ultrarunners was lower than the percent decreases in skinfold thickness reported for ultraswimmers and ultracyclists. PMID:24198597

  8. Constraining density and velocity jumps across the 410 km discontinuity

    NASA Astrophysics Data System (ADS)

    Saki, Morvarid; Thomas, Christine; Cobden, Laura; Abreu, Rafael

    2016-04-01

    We investigate the velocity and density structure of the olivine-to-wadsleyite transition using polarities of precursor arrivals to PP seismic waves that reflect off the 410 km discontinuity beneath the Northern Atlantic. Numerous source-receiver combinations have been used in order to collect a dataset of reflection points beneath our investigation area. We analyzed over 1700 seismograms from Mw > 5.8 using array seismology methods to enhance the signal to noise ratio. For each event the polarity of the PP phase is compared to polarity of the precursor signal and we find several events where the polarity of the precursors are opposite to that of PP. There does not seem to be any dependency of the observed polarities on the propagation direction of the seismic waves but interestingly there seems to be a dependency on the distance between source and receiver. The events with epicentral distances greater than 119 degrees mostly show opposite polarities, while for those with smaller epicentral distances the same polarity of the main phase and precursor signal is dominant. Using Zeoppritz equations, we analyzed more than 64 million combinations of density, compressional and shear wave velocities for both layers, above and below the 410 km discontinuity in order to find the best combination of those parameters that can explain the observations. The results are indicating combinations of density, P and S wave velocity exhibiting a smaller contrast compared to those from the pyrolite model (the density jump, however is still positive to provide physically meaningful results). The calculated reductions in both compressional and shear wave velocities go up to 13% but mostly fall within the range of less than 7- 8%. We interpret this reduction in elastic properties and seismic velocity of minerals as the effect of a higher than normal content of water of wadsleyite in this region, while we can exclude a reduction in iron.

  9. Taming the 1.2 m Telescope

    NASA Astrophysics Data System (ADS)

    Griffin, S.; Edwards, M.; Greenwald, D.; Kono, D.; Liang, D.; Lohnes, K.; Wright, V.; Spillar, E.

    2013-09-01

    Achievable residual jitter on the 1.2 m telescope at MSSS shown in Figure 1 has historically been limited to 10-20 arc-sec. peak in moderate wind conditions due to the combination of the dynamics associated with the twin telescopes on the common declination axis shaft, and the related control system behavior. Figure 1 1.2 m Telescope The lightly damped, low frequency fundamental vibration mode shape of the telescopes rotating out of phase on the common declination axis shaft severely degraded the performance of the prior controllers. This vibration mode is easily excited by external forces such as wind loading and internal torque commands from the mount control system. The relatively poor historic performance was due to a combination of the low error rejection of external disturbances, and the controller exciting the mode. A radical new approach has been implemented that has resulted in a decrease of jitter to less than 1 arcsec under most conditions. The new approach includes minor hardware modifications to provide active damping with accelerometers as feedback sensors. This architecture has allowed a bandwidth increase of almost an order of magnitude and eliminated the large amplitude motions at the mode natural frequency, resulting in much improved pointing and jitter performance. A representative comparison of historical versus new architecture performance is shown in Figure 2 for the declination axis.

  10. Subduction of European continental crust to 70 km depth imaged in the Western Alps

    NASA Astrophysics Data System (ADS)

    Paul, Anne; Zhao, Liang; Guillot, Stéphane; Solarino, Stefano

    2015-04-01

    The first conclusive evidence in support of the burial (and exhumation) of continental crust to depths larger than 90 km was provided by the discovery of coesite-bearing metamorphic rocks in the Dora Maira massif of the Western Alps (Chopin, 1984). Since then, even though similar outcrops of exhumed HP/UHP rocks have been recognized in a number of collisional belts, direct seismic evidences for subduction of continental crust in the mantle of the upper plate remain rare. In the Western Alps, the greatest depth ever recorded for the European Moho is 55 km by wide-angle seismic reflection (ECORS-CROP DSS Group, 1989). In an effort to image the European Moho at greater depth, and unravel the very complex lithospheric structure of the W-Alps, we have installed the CIFALPS temporary seismic array across the Southwestern Alps for 14 months (2012-2013). The almost linear array runs from the Rhône valley (France) to the Po plain (Italy) across the Dora Maira massif where exhumed HP/UHP metamorphic rocks of continental origin were first discovered. We used the receiver function processing technique that enhances P-to-S converted waves at velocity boundaries beneath the array. The receiver function records were migrated to depth using 4 different 1-D velocity models to account for the strongest structural changes along the profile. They were then stacked using the classical common-conversion point technique. Beneath the Southeast basin and the external zones, the obtained seismic section displays a clear converted phase on the European Moho, dipping gently to the ENE from ~35 km at the western end of the profile, to ~40 km beneath the Frontal Penninic thrust (FPT). The Moho dip then noticeably increases beneath the internal zones, while the amplitude of the converted phase weakens. The weak European Moho signal may be traced to 70-75 km depth beneath the eastern Dora Maira massif and the westernmost Po plain. At shallower level (20-40 km), we observe a set of strong

  11. SoilGrids1km — Global Soil Information Based on Automated Mapping

    PubMed Central

    Hengl, Tomislav; de Jesus, Jorge Mendes; MacMillan, Robert A.; Batjes, Niels H.; Heuvelink, Gerard B. M.; Ribeiro, Eloi; Samuel-Rosa, Alessandro; Kempen, Bas; Leenaars, Johan G. B.; Walsh, Markus G.; Gonzalez, Maria Ruiperez

    2014-01-01

    Background Soils are widely recognized as a non-renewable natural resource and as biophysical carbon sinks. As such, there is a growing requirement for global soil information. Although several global soil information systems already exist, these tend to suffer from inconsistencies and limited spatial detail. Methodology/Principal Findings We present SoilGrids1km — a global 3D soil information system at 1 km resolution — containing spatial predictions for a selection of soil properties (at six standard depths): soil organic carbon (g kg−1), soil pH, sand, silt and clay fractions (%), bulk density (kg m−3), cation-exchange capacity (cmol+/kg), coarse fragments (%), soil organic carbon stock (t ha−1), depth to bedrock (cm), World Reference Base soil groups, and USDA Soil Taxonomy suborders. Our predictions are based on global spatial prediction models which we fitted, per soil variable, using a compilation of major international soil profile databases (ca. 110,000 soil profiles), and a selection of ca. 75 global environmental covariates representing soil forming factors. Results of regression modeling indicate that the most useful covariates for modeling soils at the global scale are climatic and biomass indices (based on MODIS images), lithology, and taxonomic mapping units derived from conventional soil survey (Harmonized World Soil Database). Prediction accuracies assessed using 5–fold cross-validation were between 23–51%. Conclusions/Significance SoilGrids1km provide an initial set of examples of soil spatial data for input into global models at a resolution and consistency not previously available. Some of the main limitations of the current version of SoilGrids1km are: (1) weak relationships between soil properties/classes and explanatory variables due to scale mismatches, (2) difficulty to obtain covariates that capture soil forming factors, (3) low sampling density and spatial clustering of soil profile locations. However, as the Soil

  12. Fragrance material review on 1,2-ethanediol, 1-phenyl-, 1,2-diacetate.

    PubMed

    McGinty, D; Letizia, C S; Api, A M

    2012-09-01

    A toxicologic and dermatologic review of 1,2-ethanediol, 1-phenyl-, 1,2-diacetate when used as a fragrance ingredient is presented. 1,2-Ethanediol, 1-phenyl-, 1,2-diacetate is a member of the fragrance structural group Aryl Alkyl Alcohol Simple Acid Esters (AAASAE). The AAASAE fragrance ingredients are prepared by reacting an aryl alkyl alcohol with a simple carboxylic acid (a chain of 1-4 carbons) to generate formate, acetate, propionate, butyrate, isobutyrate and carbonate esters. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for 1,2-ethanediol, 1-phenyl-, 1,2-diacetate were evaluated, then summarized, and includes physical properties data. A safety assessment of the entire AAASAE will be published simultaneously with this document. Please refer to Belsito et al. (2012) for an overall assessment of the safe use of this material and all AAASAE fragrances.

  13. Evaluation of the 7-km GEOS-5 Nature Run

    NASA Technical Reports Server (NTRS)

    Gelaro, Ronald; Putman, William M.; Pawson, Steven; Draper, Clara; Molod, Andrea; Norris, Peter M.; Ott, Lesley; Prive, Nikki; Reale, Oreste; Achuthavarier, Deepthi; Bosilovich, Michael; Buchard, Virginie; Chao, Winston; Coy, Lawrence; Cullather, Richard; da Silva, Arlindo; Darmenov, Anton; Koster, Randal; McCarty, Will; Schubert, Siegfried

    2015-01-01

    This report documents an evaluation by the Global Modeling and Assimilation Office (GMAO) of a two-year 7-km-resolution non-hydrostatic global mesoscale simulation produced with the Goddard Earth Observing System (GEOS-5) atmospheric general circulation model. The simulation was produced as a Nature Run for conducting observing system simulation experiments (OSSEs). Generation of the GEOS-5 Nature Run (G5NR) was motivated in part by the desire of the OSSE community for an improved high-resolution sequel to an existing Nature Run produced by the European Centre for Medium-Range Weather Forecasts (ECMWF), which has served the community for several years. The intended use of the G5NR in this context is for generating simulated observations to test proposed observing system designs regarding new instruments and their deployments. Because NASA's interest in OSSEs extends beyond traditional weather forecasting applications, the G5NR includes, in addition to standard meteorological components, a suite of aerosol types and several trace gas concentrations, with emissions downscaled to 10 km using ancillary information such as power plant location, population density and night-light information. The evaluation exercise described here involved more than twenty-five GMAO scientists investigating various aspects of the G5NR performance, including time mean temperature and wind fields, energy spectra, precipitation and the hydrological cycle, the representation of waves, tropical cyclones and midlatitude storms, land and ocean surface characteristics, the representation and forcing effects of clouds and radiation, dynamics of the stratosphere and mesosphere, and the representation of aerosols and trace gases. Comparisons are made with observational data sets when possible, as well as with reanalyses and other long model simulations. The evaluation is broad in scope, as it is meant to assess the overall realism of basic aspects of the G5NR deemed relevant to the conduct of OSSEs

  14. Vertical profiles of H2O, H2SO4, and sulfuric acid concentration at 45-75 km on Venus

    NASA Astrophysics Data System (ADS)

    Krasnopolsky, Vladimir A.

    2015-05-01

    A method developed by Krasnopolsky and Pollack (Krasnopolsky, V.A., Pollack, J.B. [1994]. Icarus 109, 58-78) to model vertical profiles of H2O and H2SO4 vapors and sulfuric acid concentration in the Venus cloud layer has been updated with improved thermodynamic parameters for H2O and H2SO4 and reduced photochemical production of sulfuric acid. The model is applied to the global-mean conditions and those at the low latitudes and at 60°. Variations in eddy diffusion near the lower cloud boundary are used to simulate variability in the cloud properties and abundances of H2O and H2SO4. The best version of the model for the global-mean condition results in a lower cloud boundary (LCB) at 47.5 km, H2SO4 peak abundance of 7.5 ppm at the LCB, and H2O mixing ratios of 7 ppm at 62 km and 3.5 ppm above 67 km. The model for low latitudes gives LCB at 48.5 km, the H2SO4 peak of 5 ppm, H2O of 8.5 ppm at 62 km and 3 ppm above 67 km. The model for 60° shows LCB at 46 km, the H2SO4 peak of 8.5 ppm, H2O of 9 ppm at 62 km and 4.5 ppm above 67 km. The calculated variability is induced by the proper changes in the production of sulfuric acid (by factors of 1.2 and 0.7 for the low latitudes and 60°, respectively) and reduction of eddy diffusion near 45 km relative to the value at 54 km by factors of 1.1, 3, and 4.5 for the low and middle (global-mean) latitudes and 60°, respectively. Concentration of sulfuric acid at the low and middle latitudes varies from ∼98% near 50 km to ∼80% at 60 km and then is almost constant at 79% at 70 km. Concentration at 60° is 98% at 50 km, 73% at 63 km, and 81% at 70 km. There is a reasonable agreement between the model results and observations except for the sulfuric acid concentration in the lower clouds. Variations of eddy diffusion in the lower cloud layer simulate variations in atmospheric dynamics and may induce strong variations in water vapor near the cloud tops. Variations in temperature may affect abundances of the H2O and H2SO4 vapors

  15. Computational Studies on Nitro Derivatives of 1-Hydroxy-1,2,4-triazole

    NASA Astrophysics Data System (ADS)

    Singh, Hariji; Mukherjee, Uttama; Shankar Saini, Ravi

    2012-07-01

    Thermodynamic properties and energetics of the nitro derivatives of 1-hydroxy-1,2,4-triazole, viz. 1-hydroxy-3-nitro-1,2,4-triazole (A), 1-hydroxy-5-nitro-1,2,4-triazole (B), and 1-hydroxy-3,5-dinitro-1,2,4-triazole (C), are considered for a detailed computational study during the present investigation using a density functional theory B3LYP/6-311G(d,p) method as implemented in the Gaussian 03 suite of programs. Heats of formation and other thermodynamic properties for all of the compounds considered were determined. Studies revealed that these compounds possess the requisite properties for use as high-density energetic materials. Detonation velocity (D) and detonation pressure (P) of the title compounds were evaluated using the Kamlet-Jacobs method based on the crystal densities calculated at the DFT(B3LYP)/6-311G(d,p) level incorporating the electrostatic interaction. Calculation showed that these compounds yielded a detonation pressure and detonation velocity in the range of 27-35 GPa and ∼8 km/s, respectively, at loading densities of 1.60-1.90 g/cm3. The calculated values are comparable to the values determined for powerful commercial explosives such as Research Department Explosive (RDX) (34.10 GPa, 8.75 km/s, 1.80 g/cm3), High Melting Explosive (HMX) (39.00 GPa, 9.11 km/s, 1.89 g/cm3), and Trinitrotoluene (TNT) (21.00 GPa, 6.93 km/s, 1.64 g/cm3).

  16. Population genetic studies of the Philippine Negritos. II. gm and km allotypes of three population groups.

    PubMed Central

    Matsumoto, H; Miyazaki, T; Omoto, K; Misawa, S; Harada, S; Hirai, M; Sumpaico, J S; Medado, P M; Ogonuki, H

    1979-01-01

    Serum samples of the three tribal Negrito populations in the Philippine Islands (127 from Zambales, 87 from Bataan, and 93 from Agusan) were tested for Glm(1,2,3 and 17), and G3m(5,6,11,13,14,15,16, and 21), and Km(1). The GMpatterm of the Negritos is characterized by three haplotypes, Gm1,17;21, Gm1,2,17;21, and Gm1,3;5,11,13,14, which is also characteristic of Mongoloid-related populations, especially with high incidence of the latter haplotype. They also have the haplotype, Gm1,17;5,13,14, prevalent in Africa, New Guinea, and northern Australia, suggesting an ancient link between the Negritos and the New Guinean-Australian group. Two unusual samples of G3m(15) positive without G3m(16) observed in Zambales Negritos suggest the presence of Gm1,17;5,11,13,14,15 haplotype in the population. This appears to be unique to Zambales Negritos and the first such samples to be found. PMID:433923

  17. KM3NeT Digital Optical Module electronics

    NASA Astrophysics Data System (ADS)

    Real, Diego

    2016-04-01

    The KM3NeT collaboration is currently building of a neutrino telescope with a volume of several cubic kilometres at the bottom of the Mediterranean Sea. The telescope consists of a matrix of Digital Optical Modules that will detect the Cherenkov light originated by the interaction of the neutrinos in the proximity of the detector. This contribution describes the main components of the read-out electronics of the Digital Optical Module: the Power Board, which delivers all the power supply required by the Digital Optical Molule electronics; the Central Logic Board, the main core of the read-out system, hosting 31 Time to Digital Converters with 1 ns resolution and the White Rabbit protocol embedded in the Central Logic Board Field Programmable Gate Array; the Octopus boards, that transfer the Low Voltage Digital Signals from the PMT bases to the Central Logic Board and finally the PMT bases, in charge of converting the analogue signal produced in the 31 3" PMTs into a Low Voltage Digital Signal.

  18. Stratospheric microbiology at 20 km over the Pacific Ocean

    USGS Publications Warehouse

    Smith, David J.; Griffin, Dale W.; Schuerger, Andrew C.

    2010-01-01

    An aerobiology sampling flight at 20 km was conducted on 28 April 2008 over the Pacific Ocean (36.5° N, 118–149° W), a period of time that coincided with the movement of Asian dust across the ocean. The aim of this study was to confirm the presence of viable bacteria and fungi within a transoceanic, atmospheric bridge and to improve the resolution of flight hardware processing techniques. Isolates of the microbial strains recovered were analyzed with ribosomal ribonucleic acid (rRNA) sequencing to identify bacterial species Bacillus sp., Bacillus subtilis, Bacillus endophyticus, and the fungal genus Penicillium. Satellite imagery and ground-based radiosonde observations were used to measure dust movement and characterize the high-altitude environment at the time of collection. Considering the atmospheric residency time (7–10 days), the extreme temperature regime of the environment (-75°C), and the absence of a mechanism that could sustain particulates at high altitude, it is unlikely that our samples indicate a permanent, stratospheric ecosystem. However, the presence of viable fungi and bacteria in transoceanic stratosphere remains relevant to understanding the distribution and extent of microbial life on Earth.

  19. A 233 km tunnel for lepton and hadron colliders

    SciTech Connect

    Summers, D. J.; Cremaldi, L. M.; Datta, A.; Duraisamy, M.; Luo, T.; Lyons, G. T.

    2012-12-21

    A decade ago, a cost analysis was conducted to bore a 233 km circumference Very Large Hadron Collider (VLHC) tunnel passing through Fermilab. Here we outline implementations of e{sup +}e{sup -}, pp-bar , and {mu}{sup +}{mu}{sup -} collider rings in this tunnel using recent technological innovations. The 240 and 500 GeV e{sup +}e{sup -} colliders employ Crab Waist Crossings, ultra low emittance damped bunches, short vertical IP focal lengths, superconducting RF, and low coercivity, grain oriented silicon steel/concrete dipoles. Some details are also provided for a high luminosity 240 GeV e{sup +}e{sup -} collider and 1.75 TeV muon accelerator in a Fermilab site filler tunnel. The 40 TeV pp-bar collider uses the high intensity Fermilab p-bar source, exploits high cross sections for pp-bar production of high mass states, and uses 2 Tesla ultra low carbon steel/YBCO superconducting magnets run with liquid neon. The 35 TeV muon ring ramps the 2 Tesla superconducting magnets at 9 Hz every 0.4 seconds, uses 250 GV of superconducting RF to accelerate muons from 1.75 to 17.5 TeV in 63 orbits with 71% survival, and mitigates neutrino radiation with phase shifting, roller coaster motion in a FODO lattice.

  20. Nausea is associated with endotoxemia during a 161-km ultramarathon.

    PubMed

    Stuempfle, Kristin J; Valentino, Taylor; Hew-Butler, Tamara; Hecht, Frederick M; Hoffman, Martin D

    2016-09-01

    This study explored possible contributing factors to gastrointestinal distress, including endotoxemia, hyperthermia, dehydration and nutrition, during a 161-km ultramarathon. Thirty runners participated in the study and 20 finished the race. At three checkpoints and the finish, runners were interviewed to assess the incidence and severity of 12 gastrointestinal symptoms and to determine dietary intake. Core temperature was measured at the same locations. Runners were weighed pre-race, at the three checkpoints and the finish to monitor hydration status. Blood markers for endotoxemia (sCD14) and inflammation (interleukin-6 and C-reactive protein) were measured pre- and post-race. Gastrointestinal symptoms were experienced by most runners (80%), with nausea being the most common complaint (60%). Runners with nausea experienced significantly greater (P = 0.02) endotoxemia than those without nausea (sCD14 mean increase 0.7 versus 0.5 µg · mL(-1)). There was a significant positive correlation (r = 0.652, P = 0.005) between nausea severity and endotoxemia level. Inflammatory response, core temperature, hydration level and race diet were similar between runners with and without nausea. This study links endotoxemia to nausea in ultramarathon runners. Other possible contributing factors to nausea such as hyperthermia, dehydration and nutrition did not appear to play a role in the symptomatic runners in this study. PMID:26707127

  1. ASIC design in the KM3NeT detector

    NASA Astrophysics Data System (ADS)

    Gajanana, D.; Gromov, V.; Timmer, P.

    2013-02-01

    In the KM3NeT project [1], Cherenkov light from the muon interactions with transparent matter around the detector, is used to detect neutrinos. Photo multiplier tubes (PMT) used as photon sensor, are housed in a glass sphere (aka Optical Module) to detect single photons from the Cherenkov light. The PMT needs high operational voltage ( ~ 1.5 kV) and is generated by a Cockroft-Walton (CW) multiplier circuit. The electronics required to control the PMT's and collect the signals is integrated in two ASIC's namely: 1) a front-end mixed signal ASIC (PROMiS) for the readout of the PMT and 2) an analog ASIC (CoCo) to generate pulses for charging the CW circuit and to control the feedback of the CW circuit. In this article, we discuss the two integrated circuits and test results of the complete setup. PROMiS amplifies the input charge, converts it to a pulse width and delivers the information via LVDS signals. These LVDS signals carry accurate information on the Time of arrival ( < 2 ns) and Time over Threshold. A PROM block provides unique identification to the chip. The chip communicates with the control electronics via an I2C bus. This unique combination of the ASIC's results in a very cost and power efficient PMT base design.

  2. Topography of the 660-km seismic discontinuity beneath Izu-Bonin: Implications for tectonic history and slab deformation

    NASA Astrophysics Data System (ADS)

    Castle, John C.; Creager, Kenneth C.

    1998-06-01

    We analyze the P wave codas of 65 paths from deep northwestern Pacific earthquakes recorded by arrays of stations in Germany, the western United States, India, and Turkmenistan. We identify a phase resulting from a near-source S-to-P conversion at a nearly horizontal discontinuity ranging in depth from 650 to 730 km, which we interpret as a thermally depressed spinel to perovskite and magnesiowüstite phase transition. We migrate these data along with 39 more from Wicks and Richards [1993], accounting for three-dimensional ray bending by the sloping discontinuity, to produce a high-resolution topography map of the 660-km discontinuity in the Izu-Bonin region. Assuming an equilibrium phase transition, we interpret the discontinuity depth in terms of local temperatures. The slab, if defined by a thermal anomaly greater than -400°K, is only about 100 km thick near 28°N suggesting the slab is penetrating into the lower mantle with little or no advective thickening. Farther to the north, however, cold material appears spread out over a wide region, consistent with the slab having been laid down flat on the 660-km discontinuity as the trench retreated 2000 km eastward. Both the narrow slab to the south and the flat-lying slab to the north are consistent with recent high-resolution tomographic images. The depression to 745 km along the arc is consistent with a maximum thermal anomaly of about 1100°K. Along the entire arc, the depression occurs directly beneath the deepest earthquakes, even where seismicity is dipping at 45° and stops at 450 km depth, suggesting that the slab steepens to a vertical dip at the deepest seismicity. This change to a vertical orientation suggests that the slab loses strength temporarily through a physical process which causes the seismicity to increase dramatically and then abruptly cease.

  3. Wide-Bandgap Semiconductors

    SciTech Connect

    Chinthavali, M.S.

    2005-11-22

    With the increase in demand for more efficient, higher-power, and higher-temperature operation of power converters, design engineers face the challenge of increasing the efficiency and power density of converters [1, 2]. Development in power semiconductors is vital for achieving the design goals set by the industry. Silicon (Si) power devices have reached their theoretical limits in terms of higher-temperature and higher-power operation by virtue of the physical properties of the material. To overcome these limitations, research has focused on wide-bandgap materials such as silicon carbide (SiC), gallium nitride (GaN), and diamond because of their superior material advantages such as large bandgap, high thermal conductivity, and high critical breakdown field strength. Diamond is the ultimate material for power devices because of its greater than tenfold improvement in electrical properties compared with silicon; however, it is more suited for higher-voltage (grid level) higher-power applications based on the intrinsic properties of the material [3]. GaN and SiC power devices have similar performance improvements over Si power devices. GaN performs only slightly better than SiC. Both SiC and GaN have processing issues that need to be resolved before they can seriously challenge Si power devices; however, SiC is at a more technically advanced stage than GaN. SiC is considered to be the best transition material for future power devices before high-power diamond device technology matures. Since SiC power devices have lower losses than Si devices, SiC-based power converters are more efficient. With the high-temperature operation capability of SiC, thermal management requirements are reduced; therefore, a smaller heat sink would be sufficient. In addition, since SiC power devices can be switched at higher frequencies, smaller passive components are required in power converters. Smaller heat sinks and passive components result in higher-power-density power converters

  4. One-Hundred-km-Scale Basins on Enceladus: Evidence for an Active Ice Shell

    NASA Technical Reports Server (NTRS)

    Schenk, Paul M.; McKinnon, William B.

    2009-01-01

    Stereo-derived topographic mapping of 50% of Enceladus reveals at least 6 large-scale, ovoid depressions (basins) 90-175 km across and 800-to-1500 m deep and uncorrelated with geologic boundaries. Their shape and scale are inconsistent with impact, geoid deflection, or with dynamically supported topography. Isostatic thinning of Enceladus ice shell associated with upwellings (and tidally-driven ice melting) can plausibly account for the basins. Thinning implies upwarping of the base of the shell of 10-20 km beneath the depressions, depending on total shell thickness; loss of near-surface porosity due to enhanced heat flow may also contribute to basin lows. Alternatively, the basins may overly cold, inactive, and hence denser ice, but thermal isostasy alone requires thermal expansion more consistent with clathrate hydrate than water ice. In contrast to the basins, the south polar depression (SPD) is larger (350 wide) and shallower (0.4-to-0.8 km deep) and correlates with the area of tectonic deformation and active resurfacing. The SPD also differs in that the floor is relatively flat (i.e., conforms roughly to the global triaxial shape, or geoid) with broad, gently sloping flanks. The relative flatness across the SPD suggests that it is in or near isostatic equilibrium, and underlain by denser material, supporting the polar sea hypothesis of Collins and Goodman. Near flatness is also predicted by a crustal spreading origin for the "tiger stripes (McKinnon and Barr 2007, Barr 2008); the extraordinary, high CIRS heat flows imply half-spreading rates in excess of 10 cm/yr, a very young surface age (250,000 yr), and a rather thin lithosphere (hence modest thermal topography). Topographic rises in places along the outer margin of the SPD correlate with parallel ridges and deformation along the edge of the resurfaced terrain, consistent with a compressional, imbricate thrust origin for these ridges, driven by the spreading.

  5. Development of a global land cover characteristics database and IGBP DISCover from 1 km AVHRR data

    USGS Publications Warehouse

    Loveland, T.R.; Reed, B.C.; Brown, J.F.; Ohlen, D.O.; Zhu, Z.; Yang, L.; Merchant, J.W.

    2000-01-01

    Researchers from the U.S. Geological Survey, University of Nebraska-Lincoln and the European Commission's Joint Research Centre, Ispra, Italy produced a 1 km resolution global land cover characteristics database for use in a wide range of continental- to global-scale environmental studies. This database provides a unique view of the broad patterns of the biogeographical and ecoclimatic diversity of the global land surface, and presents a detailed interpretation of the extent of human development. The project was carried out as an International Geosphere-Biosphere Programme, Data and Information Systems (IGBP-DIS) initiative. The IGBP DISCover global land cover product is an integral component of the global land cover database. DISCover includes 17 general land cover classes defined to meet the needs of IGBP core science projects. A formal accuracy assessment of the DISCover data layer will be completed in 1998. The 1 km global land cover database was developed through a continent-by-continent unsupervised classification of 1 km monthly Advanced Very High Resolution Radiometer (AVHRR) Normalized Difference Vegetation Index (NDVI) composites covering 1992-1993. Extensive post-classification stratification was necessary to resolve spectral/temporal confusion between disparate land cover types. The complete global database consists of 961 seasonal land cover regions that capture patterns of land cover, seasonality and relative primary productivity. The seasonal land cover regions were aggregated to produce seven separate land cover data sets used for global environmental modelling and assessment. The data sets include IGBP DISCover, U.S. Geological Survey Anderson System, Simple Biosphere Model, Simple Biosphere Model 2, Biosphere-Atmosphere Transfer Scheme, Olson Ecosystems and Running Global Remote Sensing Land Cover. The database also includes all digital sources that were used in the classification. The complete database can be sourced from the website: http://edcwww.cr.usgs.gov/landdaac/glcc/glcc.html.

  6. File Specification for the 7-km GEOS-5 Nature Run, Ganymed Release Non-Hydrostatic 7-km Global Mesoscale Simulation

    NASA Technical Reports Server (NTRS)

    da Silva, Arlindo M.; Putman, William; Nattala, J.

    2014-01-01

    This document describes the gridded output files produced by a two-year global, non-hydrostatic mesoscale simulation for the period 2005-2006 produced with the non-hydrostatic version of GEOS-5 Atmospheric Global Climate Model (AGCM). In addition to standard meteorological parameters (wind, temperature, moisture, surface pressure), this simulation includes 15 aerosol tracers (dust, sea-salt, sulfate, black and organic carbon), O3, CO and CO2. This model simulation is driven by prescribed sea-surface temperature and sea-ice, daily volcanic and biomass burning emissions, as well as high-resolution inventories of anthropogenic sources. A description of the GEOS-5 model configuration used for this simulation can be found in Putman et al. (2014). The simulation is performed at a horizontal resolution of 7 km using a cubed-sphere horizontal grid with 72 vertical levels, extending up to to 0.01 hPa (approximately 80 km). For user convenience, all data products are generated on two logically rectangular longitude-latitude grids: a full-resolution 0.0625 deg grid that approximately matches the native cubed-sphere resolution, and another 0.5 deg reduced-resolution grid. The majority of the full-resolution data products are instantaneous with some fields being time-averaged. The reduced-resolution datasets are mostly time-averaged, with some fields being instantaneous. Hourly data intervals are used for the reduced-resolution datasets, while 30-minute intervals are used for the full-resolution products. All full-resolution output is on the model's native 72-layer hybrid sigma-pressure vertical grid, while the reduced-resolution output is given on native vertical levels and on 48 pressure surfaces extending up to 0.02 hPa. Section 4 presents additional details on horizontal and vertical grids. Information of the model surface representation can be found in Appendix B. The GEOS-5 product is organized into file collections that are described in detail in Appendix C. Additional

  7. Kinematics of the New Zealand plate boundary: Relative motion by GPS across networks of 1000 km and 50 km spacing

    NASA Technical Reports Server (NTRS)

    Meertens, Charles M.; Rocken, Christian; Perin, Barbara; Walcott, Richard

    1993-01-01

    The NASA/DOSE 'Kinematics of the New Zealand Plate Boundary' experiment is a four-year cooperative Global Positioning System (GPS) experiment involving 6 universities and institutions in New Zealand and the United States. The investigation covers two scales, the first on the scale of plates (approximately 1000 km) and the second is on the scale of the plate boundary zone (approximately 50 km). In the first portion of the experiment, phase A, the objective is to make direct measurements of tectonic plate motion between the Australian and Pacific plates using GPS in order to determine the Euler vector of this plate pair. The phase A portion of this experiment was initiated in December 1992 with the first-epoch baseline measurements on the large scale network. The network will be resurveyed two years later to obtain velocities. The stations which were observed for phase A are shown and listed. Additional regional stations which will be used for this study are listed and are part of either CIGNET or other global tracking networks. The phase A portion of the experiment is primarily the responsibility of the UNAVCO investigators. Therefore, this report concentrates on phase A. The first year of NASA funding for phase A included only support for the field work. Processing and analysis will take place with the second year of funding. The second part of the experiemnt measured relative motion between the Australian and Pacific plates across the pate boundary zone between Hokitika and Christchurch on the South Island of New Zealand. The extent and rate of deformation will be determined by comparisons with historical, conventional surveys and by repeated GPS measurements to be made in two years. This activity was the emphasis of the LDGO portion of the study. An ancillary experiment, phase C, concentrated on plate boundary deformation in the vicinity of Wellington and was done as part of training during the early portion of the field campaign. Details of the objectives of the

  8. The 1.2 micron CMOS technology

    NASA Technical Reports Server (NTRS)

    Pina, C. A.

    1985-01-01

    A set of test structures was designed using the Jet Propulsion Laboratory (JPL) test chip assembler and was used to evaluate the first CMOS-bulk foundry runs with feature sizes of 1.2 microns. In addition to the problems associated with the physical scaling of the structures, this geometry provided an additional set of problems, since the design files had to be generated in such a way as to be capable of being processed through p-well, n-well, and twin-well processing lines. This requirement meant that the files containing the geometric design rules as well as the structure design files had to produce process-insensitive designs, a requirement that does not apply to the more mature 3.0-micron CMOS feature size technology. Because of the photolithographic steps required with this feature size, the maximum allowable chip size was 10 x 10 mm, and this chip was divided into 24 project areas, with each area being 1.6 x 1.6 mm in size. The JPL-designed structures occupied 13 out of the 21 allowable project sizes and provided the only test information obtained from these three preliminary runs. The structures were used to successfully evaluate three different manufacturing runs through two separate foundries.

  9. Dehalogenimonas spp. can Reductively Dehalogenate High Concentrations of 1,2-Dichloroethane, 1,2-Dichloropropane, and 1,1,2-Trichloroethane

    PubMed Central

    2012-01-01

    The contaminant concentrations over which type strains of the species Dehalogenimonas alkenigignens and Dehalogenimonas lykanthroporepellens were able to reductively dechlorinate 1,2-dichloroethane (1,2-DCA), 1,2-dichloropropane (1,2-DCP), and 1,1,2-trichloroethane (1,1,2-TCA) were evaluated. Although initially isolated from an environment with much lower halogenated solvent concentrations, D. alkenigignens IP3-3T was found to reductively dehalogenate chlorinated alkanes at concentrations comparable to D. lykanthroporepellens BL-DC-9T. Both species dechlorinated 1,2-DCA, 1,2-DCP, and 1,1,2-TCA present at initial concentrations at least as high as 8.7, 4.0, and 3.5 mM, respectively. The ability of Dehalogenimonas spp. to carry out anaerobic reductive dechlorination even in the presence of high concentrations of chlorinated aliphatic alkanes has important implications for remediation of contaminated soil and groundwater. PMID:23046725

  10. Dehalogenimonas spp. can Reductively Dehalogenate High Concentrations of 1,2-Dichloroethane, 1,2-Dichloropropane, and 1,1,2-Trichloroethane.

    PubMed

    Maness, Andrew D; Bowman, Kimberly S; Yan, Jun; Rainey, Fred A; Moe, William M

    2012-01-01

    The contaminant concentrations over which type strains of the species Dehalogenimonas alkenigignens and Dehalogenimonas lykanthroporepellens were able to reductively dechlorinate 1,2-dichloroethane (1,2-DCA), 1,2-dichloropropane (1,2-DCP), and 1,1,2-trichloroethane (1,1,2-TCA) were evaluated. Although initially isolated from an environment with much lower halogenated solvent concentrations, D. alkenigignens IP3-3T was found to reductively dehalogenate chlorinated alkanes at concentrations comparable to D. lykanthroporepellens BL-DC-9T. Both species dechlorinated 1,2-DCA, 1,2-DCP, and 1,1,2-TCA present at initial concentrations at least as high as 8.7, 4.0, and 3.5 mM, respectively. The ability of Dehalogenimonas spp. to carry out anaerobic reductive dechlorination even in the presence of high concentrations of chlorinated aliphatic alkanes has important implications for remediation of contaminated soil and groundwater. PMID:23046725

  11. Dehalogenimonas spp. can Reductively Dehalogenate High Concentrations of 1,2-Dichloroethane, 1,2-Dichloropropane, and 1,1,2-Trichloroethane.

    PubMed

    Maness, Andrew D; Bowman, Kimberly S; Yan, Jun; Rainey, Fred A; Moe, William M

    2012-01-01

    The contaminant concentrations over which type strains of the species Dehalogenimonas alkenigignens and Dehalogenimonas lykanthroporepellens were able to reductively dechlorinate 1,2-dichloroethane (1,2-DCA), 1,2-dichloropropane (1,2-DCP), and 1,1,2-trichloroethane (1,1,2-TCA) were evaluated. Although initially isolated from an environment with much lower halogenated solvent concentrations, D. alkenigignens IP3-3T was found to reductively dehalogenate chlorinated alkanes at concentrations comparable to D. lykanthroporepellens BL-DC-9T. Both species dechlorinated 1,2-DCA, 1,2-DCP, and 1,1,2-TCA present at initial concentrations at least as high as 8.7, 4.0, and 3.5 mM, respectively. The ability of Dehalogenimonas spp. to carry out anaerobic reductive dechlorination even in the presence of high concentrations of chlorinated aliphatic alkanes has important implications for remediation of contaminated soil and groundwater.

  12. TEVA-SPOT Toolkit 1.2

    2007-07-26

    The TEVA-SPOT Toolkit (SPOT) supports the design of contaminant warning systems (CWSs) that use real-time sensors to detect contaminants in municipal water distribution networks. Specifically, SPOT provides the capability to select the locations for installing sensors in order to maximize the utility and effectiveness of the CWS. SPOT models the sensor placement process as an optimization problem, and the user can specify a wide range of performance objectives for contaminant warning system design, including populationmore » health effects, time to detection, extent of contamination, volume consumed and number of failed detections. For example, a SPOT user can integrate expert knowledge during the design process by specigying required sensor placements or designating network locations as forbidden. Further, cost considerations can be integrated by limiting the design with user-specified installation costs at each location.« less

  13. A high resolution (1 km) groundwater model for Indonesia

    NASA Astrophysics Data System (ADS)

    Sutanudjaja, Edwin; Verkaik, Jarno; de Graaf, Inge; van Beek, Rens; Erkens, Gilles; Bierkens, Marc

    2015-04-01

    Groundwater is important in many parts of Indonesia. It serves as a primary source of drinking water and industrial activities. During times of drought, it sustains water flows in streams, rivers, lakes and wetlands, and thus support ecosystem habitat and biodiversity as well as preventing hazardous forest fire. Besides its importance, groundwater is known as a vulnerable resource as unsustainable groundwater exploitation and management occurs in many areas of the country. Therefore, in order to ensure sustainable management of groundwater resources, monitoring and predicting groundwater changes in Indonesia are imperative. However, large extent groundwater models to assess these changes on a regional scale are almost non-existent and are hampered by the strong topographical and lithological transitions that characterize Indonesia. In this study, we built an 1 km resolution groundwater model for the entire Indonesian archipelago (total inland area: about 2 million km2). We adopted the approaches of Sutanudjaja et al. (2011, 2014a) and de Graaf et al. (2014) in order to make a MODFLOW (Harbaugh et al., 2000) groundwater model by using only global datasets. Aquifer schematization and properties of the groundwater model were developed from available global lithological maps (e.g. Dürr et al., 2005; Gleeson et al., 2011; Hartmann & Moorsdorf, 2012; Gleeson et al., 2014). We forced the groundwater model with the recent output of global hydrological model PCR-GLOBWB version 2.0 (Sutanudjaja et al., 2014b; van Beek et al., 2011), specifically the long term average of groundwater recharge and average surface water levels derived from channel discharge. Simulation results were promising. The MODFLOW model converged with realistic aquifer properties (i.e. transmissivities) and produced reasonable groundwater head spatial distribution reflecting the positions of major groundwater bodies and surface water bodies in the country. In Vienna, we aim to show and demonstrate these

  14. Processing techniques for global land 1-km AVHRR data

    USGS Publications Warehouse

    Eidenshink, Jeffery C.; Steinwand, Daniel R.; Wivell, Charles E.; Hollaren, Douglas M.; Meyer, David

    1993-01-01

    The U.S. Geological Survey's (USGS) Earth Resources Observation Systems (EROS) Data Center (EDC) in cooperation with several international science organizations has developed techniques for processing daily Advanced Very High Resolution Radiometer (AVHRR) 1-km data of the entire global land surface. These techniques include orbital stitching, geometric rectification, radiometric calibration, and atmospheric correction. An orbital stitching algorithm was developed to combine consecutive observations acquired along an orbit by ground receiving stations into contiguous half-orbital segments. The geometric rectification process uses an AVHRR satellite model that contains modules for forward mapping, forward terrain correction, and inverse mapping with terrain correction. The correction is accomplished by using the hydrologic features coastlines and lakes from the Digital Chart of the World. These features are rasterized into the satellite projection and are matched to the AVHRR imagery using binary edge correlation techniques. The resulting coefficients are related to six attitude correction parameters: roll, roll rate, pitch, pitch rate, yaw, and altitude. The image can then be precision corrected to a variety of map projections and user-selected image frames. Because the AVHRR lacks onboard calibration for the optical wavelengths, a series of time-variant calibration coefficients derived from vicarious calibration methods and are used to model the degradation profile of the instruments. Reducing atmospheric effects on AVHRR data is important. A method has been develop that will remove the effects of molecular scattering and absorption from clear sky observations, using climatological measurements of ozone. Other methods to remove the effects of water vapor and aerosols are being investigated.

  15. Gastrointestinal distress is common during a 161-km ultramarathon.

    PubMed

    Stuempfle, Kristin Jean; Hoffman, Martin Dean

    2015-01-01

    This study examined the incidence, severity, and timing of gastrointestinal (GI) symptoms in finishers and non-finishers of the 161-km Western States Endurance Run. A total of 272 runners (71.0% of starters) completed a post-race questionnaire that assessed the incidence and severity (none = 0, mild = 1, moderate = 2, severe = 3, very severe = 4) of 12 upper (reflux/heartburn, belching, stomach bloating, stomach cramps/pain, nausea, vomiting) and lower (intestinal cramps/pain, flatulence, side ache/stitch, urge to defecate, loose stool/diarrhoea, intestinal bleeding/bloody faeces) GI symptoms experienced during each of four race segments. GI symptoms were experienced by most runners (96.0%). Flatulence (65.9% frequency, mean value 1.0, s = 0.6 severity), belching (61.3% frequency, mean value 1.0, s = 0.6 severity), and nausea (60.3% frequency, mean value 1.0, s = 0.7 severity) were the most common symptoms. Among race finishers, 43.9% reported that GI symptoms affected their race performance, with nausea being the most common symptom (86.0%). Among race non-finishers, 35.6% reported that GI symptoms were a reason for dropping out of the race, with nausea being the most common symptom (90.5%). For both finishers and non-finishers, nausea was greatest during the most challenging and hottest part of the race. GI symptoms are very common during ultramarathon running, and in particular, nausea is the most common complaint for finishers and non-finishers. PMID:25716739

  16. Estimation of Land Surface Temperature from 1-km AVHRR data

    NASA Astrophysics Data System (ADS)

    Frey, Corinne

    2016-04-01

    In order to re-process DLRs 1km AVHRR data archive to different geophysical and descriptive parameters of the land surface and the atmosphere, a series of scientific data processors are being developed in the framework of the TIMELINE project. The archive of DLR ranges back to the 80ies. One of the data processors is SurfTemp, which processes L2 LST and emissivity datasets from AVHRR L1b data. The development of the data processor included the selection of statistical procedures suitable for time series processing, including four mono-window and six split window algorithms. For almost all of these algorithms, new constants were generated, which better account for different atmospheric and geometric acquisition situations. The selection of optimal algorithms for SurfTemp is based on a round robin approach, in which the selected mono-window and split window algorithms are tested on the basis of a large number of TOA radiance/LST pairs, which were generated using a radiative transfer model and the SeeBorV5 profile database. The original LSTs are thereby compared to the LSTs derived from the TOA radiances using the mono- and split window algorithms. The algorithm comparison includes measures of precision, as well as the sensitivity of a method to the accuracy of its input data. The results of the round robin are presented, as well as the implementation of selected algorithms into SurfTemp. Further, first cross-validation results between the AVHRR LST and MODIS LST are shown.

  17. Substrate interactions in dehalogenation of 1,2-dichloroethane, 1,2-dichloropropane, and 1,1,2-trichloroethane mixtures by Dehalogenimonas spp.

    PubMed

    Dillehay, Jacob L; Bowman, Kimberly S; Yan, Jun; Rainey, Fred A; Moe, William M

    2014-04-01

    When chlorinated alkanes are present as soil or groundwater pollutants, they often occur in mixtures. This study evaluated substrate interactions during the anaerobic reductive dehalogenation of chlorinated alkanes by the type strains of two Dehalogenimonas species, D. lykanthroporepellens and D. alkenigignens. Four contaminant mixtures comprised of combinations of the chlorinated solvents 1,2-dichloroethane (1,2-DCA), 1,2-dichloropropane (1,2-DCP), and 1,1,2-trichloroethane (1,1,2-TCA) were assessed for each species. Chlorinated solvent depletion and daughter product formation determined as a function of time following inoculation into anaerobic media revealed preferential dechlorination of 1,1,2-TCA over both 1,2-DCA and 1,2-DCP for both species. 1,2-DCA in particular was not dechlorinated until 1,1,2-TCA reached low concentrations. In contrast, both species concurrently dechlorinated 1,2-DCA and 1,2-DCP over a comparably large concentration range. This is the first report of substrate interactions during chlorinated alkane dehalogenation by pure cultures, and the results provide insights into the chlorinated alkane transformation processes that may be expected for contaminant mixtures in environments where Dehalogenimonas spp. are present. PMID:23990262

  18. Clouds in ECMWF's 30 KM Resolution Global Atmospheric Forecast Model (TL639)

    NASA Technical Reports Server (NTRS)

    Cahalan, R. F.; Morcrette, J. J.

    1999-01-01

    Global models of the general circulation of the atmosphere resolve a wide range of length scales, and in particular cloud structures extend from planetary scales to the smallest scales resolvable, now down to 30 km in state-of-the-art models. Even the highest resolution models do not resolve small-scale cloud phenomena seen, for example, in Landsat and other high-resolution satellite images of clouds. Unresolved small-scale disturbances often grow into larger ones through non-linear processes that transfer energy upscale. Understanding upscale cascades is of crucial importance in predicting current weather, and in parameterizing cloud-radiative processes that control long term climate. Several movie animations provide examples of the temporal and spatial variation of cloud fields produced in 4-day runs of the forecast model at the European Centre for Medium-Range Weather Forecasts (ECMWF) in Reading, England, at particular times and locations of simultaneous measurement field campaigns. model resolution is approximately 30 km horizontally (triangular truncation TL639) with 31 vertical levels from surface to stratosphere. Timestep of the model is about 10 minutes, but animation frames are 3 hours apart, at timesteps when the radiation is computed. The animations were prepared from an archive of several 4-day runs at the highest available model resolution, and archived at ECMWF. Cloud, wind and temperature fields in an approximately 1000 km X 1000 km box were retrieved from the archive, then approximately 60 Mb Vis5d files were prepared with the help of Graeme Kelly of ECMWF, and were compressed into MPEG files each less than 3 Mb. We discuss the interaction of clouds and radiation in the model, and compare the variability of cloud liquid as a function of scale to that seen in cloud observations made in intensive field campaigns. Comparison of high-resolution global runs to cloud-resolving models, and to lower resolution climate models is leading to better

  19. The isolated ˜680 km deep 30 May 2015 MW 7.9 Ogasawara (Bonin) Islands earthquake

    NASA Astrophysics Data System (ADS)

    Ye, Lingling; Lay, Thorne; Zhan, Zhongwen; Kanamori, Hiroo; Hao, Jin-Lai

    2016-01-01

    Deep-focus earthquakes, located in very high-pressure conditions 300 to 700 km below the Earth's surface within sinking slabs of relatively cold oceanic lithosphere, are mysterious phenomena. The largest recorded deep-focus earthquake (MW 7.9) in the Izu-Bonin slab struck on 30 May 2015 beneath the Ogasawara (Bonin) Islands, isolated from prior seismicity by over 100 km in depth, and followed by only a few small aftershocks. Globally, this is the deepest (680 km centroid depth) event with MW ≥ 7.8 in the seismological record. Seismicity indicates along-strike contortion of the Izu-Bonin slab, with horizontal flattening near a depth of 550 km in the Izu region and rapid steepening to near-vertical toward the south above the location of the 2015 event. This event was exceptionally well-recorded by seismic stations around the world, allowing detailed constraints to be placed on the source process. Analyses of a large global data set of P, SH and pP seismic phases using short-period back-projection, subevent directivity, and broadband finite-fault inversion indicate that the mainshock ruptured a shallowly-dipping fault plane with patchy slip that spread over a distance of ˜40 km with a multi-stage expansion rate (˜ 5 + km /s down-dip initially, ˜3 km/s up-dip later). During the 17 s total rupture duration the radiated energy was ˜ 3.3 ×1016 J and the stress drop was ˜38 MPa. The radiation efficiency is moderate (0.34), intermediate to that of the 1994 Bolivia and 2013 Sea of Okhotsk MW 8.3 deep earthquakes, indicating that source processes of very large deep earthquakes sample a wide range of behavior from dissipative, more viscous failure to very brittle failure. The isolated occurrence of the event, much deeper than the apparently thermally-bounded distribution of Bonin-slab seismicity above 600 km depth, suggests that localized stress concentration associated with the pronounced deformation of the Izu-Bonin slab and proximity to the 660-km phase transition

  20. Survival of the Tardigrade Hypsibius Dujardini during Hypervelocity Impact Events up to 5.49 km s-1

    NASA Astrophysics Data System (ADS)

    Pasini, D.

    2014-04-01

    Studies have previously been conducted to verify the survivability of living cells during hypervelocity impact events to test the panspermia and lithopanspermia hypotheses [1, 2]. It has been demonstrated that bacteria survive impacts up to 5.4 km s-1 (approx. shock pressure 30 GPa) - albeit with a low probability of survival [1], whilst larger, more complex, objects (such as seeds) break up at ~1 km s-1 [2]. The survivability of yeast spores in impacts up to 7.4 km s-1 has also recently been shown [3]. Previous work by the authors demonstrated the survivability of Nannochloropsis Oculata Phytoplankton, a eukaryotic photosynthesizing autotroph found in the 'euphotic zone' (sunlit surface layers of oceans [4]), at impact velocities up to 6.07 km s-1 [5]. Other groups have also reported that lichens are able to survive shocks in similar pressure ranges [6]. However, whilst many simple single celled organisms have now been shown to survive such impacts (and the associated pressures) as those encountered during the migration of material from one planet to another [1, 3, 5], complex multicellular organisms have either largely not been tested or, those that have been, have not survived the process [2]. Hypsibius dujardini, like most species of tardigrade, are complex organisms composed of approximately 40,000 cells [7]. When humidity decreases they enter a highly dehydrated state known as a 'tun' and can survive extreme temperatures (as low as - 253°C or as high as 151°C), as well as exposure to Xrays and the vacuum of space [7]. Here we test the shock survivability of Hypsibius dujardini by firing a nylon projectile onto a frozen sample of water containing frozen tardigrades using a light gas gun (LGG) [8]. The recovered ice and water were then analysed under an optical microscope to check the viability of any remnant organisms that may have survived impact, and the pressures generated.

  1. 112 Gb/s PM-QPSK transmission up to 6000 km with 200 km amplifier spacing and a hybrid fiber span configuration.

    PubMed

    Downie, John D; Hurley, Jason; Cartledge, John; Bickham, Scott; Mishra, Snigdharaj

    2011-12-12

    We demonstrate transmission of 112 Gb/s PM-QPSK signals over a system with 200 km span lengths. Amplification is provided by hybrid backward-pumped Raman/EDFA amplifiers and reach lengths up to 6000 km for an 8 channel system and 5400 km for a 32 channel system are shown. As a means of maximizing OSNR, a simple hybrid fiber span configuration is used that combines two ultra-low loss fibers, one having very large effective area.

  2. Daymet: Daily Surface Weather Data on a 1-km Grid for North America, Version 2.

    NASA Astrophysics Data System (ADS)

    Devarakonda, R.

    2014-12-01

    km grid for North America, 1980-2008". Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center for Biogeochemical Dynamics (DAAC), 1. [2] Devarakonda R., et al. 2012. Daymet: Single Pixel Data Extraction Tool. Available [http://daymet.ornl.go/singlepixel.html].

  3. Electrical properties of Ba(Dy1/2Nb1/2)O3 ceramic

    NASA Astrophysics Data System (ADS)

    Nath, K. Amar; Chandra, K. P.; Dubey, K.; Prasad, K.

    2016-05-01

    Polycrystalline Ba(Dy1/2Nb1/2)O3 was prepared using a high-temperature solid-state reaction method. X-ray diffraction analysis indicated the formation of a single-phase cubic structure having space group Pm3m. AC impedance plots as a function of frequency at different temperatures were used to analyse the electrical behaviour of the sample, which indicated the negative temperature coefficient of resistance character. Complex impedance analysis targeted non-Debye type dielectric relaxation. Frequency dependent ac conductivity data obeyed Jonscher's power law. The apparent activation energy was estimated to be 0.97 eV at 1 kHz.

  4. Microwave spectrum, structural parameters, and quadrupole coupling for 1,2-dihydro-1,2-azaborine.

    PubMed

    Daly, Adam M; Tanjaroon, Chakree; Marwitz, Adam J V; Liu, Shih-Yuan; Kukolich, Stephen G

    2010-04-21

    The first microwave spectrum for 1,2-dihydro-1,2-azaborine has been measured in the frequency range 7-18 GHz, providing accurate rotational constants and nitrogen and boron quadrupole coupling strengths for three isotopomers, H(6)C(4)(11)B(14)N, H(6)C(4)(10)B(14)N, and H(5)DC(4)(11)B(14)N. The measured rotational constants were used to accurately determine coordinates for the substituted atoms and provide sufficient data to determine most of the important structural parameters for this molecule. The spectra were obtained using a pulsed beam Fourier transform microwave spectrometer, with sufficient resolution to allow accurate measurements of (14)N, (11)B, and (10)B nuclear quadrupole hyperfine interactions. High-level ab initio calculations provided structural parameters and quadrupole coupling strengths that are in very good agreement with measured values. The rotational constants for the parent compound are A = 5657.335(1), B = 5349.2807(5), and C = 2749.1281(4) MHz, yielding the inertial defect Delta(0) = 0.02 amu x A(2) for the ground-state structure. The observed near-zero and positive inertial defect clearly indicates that the molecular structure of 1,2-dihydro-1,2-azaborine is planar. The least-squares fit analysis to determine the azaborine ring structure yielded the experimental bond lengths and 2sigma errors R(B-N) = 1.45(3) A, R(B-C) = 1.51(1) A, and R(N-C) = 1.37(3) A for the ground-state structure. Interbond angles for the ring were also determined. An extended Townes-Dailey population analysis of the boron and nitrogen quadrupole coupling constants provided the valence p-electron occupancy p(c) = 0.3e for boron and p(c) = 1.3e for nitrogen.

  5. Measurement of the vertical gradient of the semidiurnal tidal wind phase in winter at the 95 km level

    NASA Astrophysics Data System (ADS)

    Schminder, R.; Kurschner, D.

    1984-05-01

    When supplemented by absolute reflection height measurements, low frequency wind measurements in the 90-100 km height range become truly competitive in comparison with the more widely used radar meteor wind observations. For example, height profiles of the wind parameters in the so-called meteor zone can be obtained due to the considerable interdiurnal variability of the average nighttime reflection heights controlled by geomagnetic activity. The phase of the semidiurnal tidal wind is particularly height-dependent. The measured vertical gradient of 1/4 h/km in winter corresponds to a vertical wavelength of about 50 km. Wind measurements in the upper atmosphere, at heights between 90 and 100 km, were carried out at the Collm Geophysical Observatory of Karl Marx University Leipzig for a number of years. These measurements use the closely-spaced receiver method and three measuring paths, on 179, 227, and 272 kHz. They take place every day between sunset and sunrise, i.e., nightly. A night in this sense may last as long as 18 hours in winter. Both the measurements and their evaluation are completely automatic, and the prevailing winds and tides are separated.

  6. Measurement of the Vertical Gradient of the Semidiurnal Tidal Wind Phase in Winter at the 95 Km Level

    NASA Technical Reports Server (NTRS)

    Schminder, R.; Kurschner, D.

    1984-01-01

    When supplemented by absolute reflection height measurements, low frequency wind measurements in the 90-100 km height range become truly competitive in comparison with the more widely used radar meteor wind observations. For example, height profiles of the wind parameters in the so-called meteor zone can be obtained due to the considerable interdiurnal variability of the average nighttime reflection heights controlled by geomagnetic activity. The phase of the semidiurnal tidal wind is particularly height-dependent. The measured vertical gradient of 1/4 h/km in winter corresponds to a vertical wavelength of about 50 km. Wind measurements in the upper atmosphere, at heights between 90 and 100 km, were carried out at the Collm Geophysical Observatory of Karl Marx University Leipzig for a number of years. These measurements use the closely-spaced receiver method and three measuring paths, on 179, 227, and 272 kHz. They take place every day between sunset and sunrise, i.e., nightly. A night in this sense may last as long as 18 hours in winter. Both the measurements and their evaluation are completely automatic, and the prevailing winds and tides are separated.

  7. Topography of the 410 and 660 km discontinuities beneath the Korean Peninsula and southwestern Japan using teleseismic receiver functions

    NASA Astrophysics Data System (ADS)

    Lee, Sang-Hyun; Rhie, Junkee; Park, Yongcheol; Kim, Kwang-Hee

    2014-09-01

    Topography of the 410 and 660 km seismic upper mantle discontinuities beneath the Korean Peninsula and southwestern Japan were determined using teleseismic receiver functions. P receiver functions were migrated from delayed times to corresponding piercing (conversion) points of P-to-S converted phases, using one-dimensional (1-D) and three-dimensional (3-D) models. Receiver functions were then stacked using Common Conversion Point (CCP) techniques, to enhance signal-to-noise ratios and thereby reduce uncertainty (noise). The 410 and 660 km discontinuities were clearly imaged, as positively valued amplitude peaks of CCP stacked receiver functions in the study area. Topographic variations were roughly consistent with the low temperature of the subducting Pacific Plate. However, the complex structure of the subducting Pacific Plate produced distinct changes of upper mantle discontinuities, which cannot be explained by temperature variations alone. Depression of the 410 km discontinuity, observed in a wide region extending from the Korean Peninsula to Kyushu Island, may be related to trench rollback history. Furthermore, the topography of the 660 km discontinuity varies significantly with latitude. At latitudes higher than 38°N, its depth remains unchanged, despite the presence of the stagnant slab, while significant depression has been observed at latitudes below 36°N. This may have been caused by differences in the angles of subduction of the Japan slab and the Izu-Bonin slab. However, heterogeneity of the water content of slabs may also have contributed to this topographical difference.

  8. Metabolism of 1,2,3,4-, 1,2,3,5-, and 1,2,4,5-tetrachlorobenzene in the squirrel monkey

    SciTech Connect

    Schwartz, H.; Chu, I.; Villeneuve, D.C.; Benoit, F.M.

    1987-01-01

    The metabolism of three tetrachlorobenzene isomers (TeCB) was investigated in the squirrel monkey. The animals were administered orally 6 single doses of /sup 14/C-labeled 1,2,3,4-, 1,2,4,5-, or 1,2,3,5-tetrachlorobenzene over a 3-wk period at levels ranging from 50 to 100 mg/kg body weight (b.w) and kept in individual metabolism cages to collect urine and feces for radioassay. Approximately 38% (1,2,3,4-TeCB), 36% (1,2,3,5-TeCB), and 18% (1,2,4,5-TeCB) of the doses were excreted respectively in the feces 48 h post administration. In monkeys dosed with 1,2,3,4-TeCB, unchanged compound accounted for 50% of the fecal radioactivity. Unchanged compound accounted for more than 50% of the fecal radioactivity found in the monkeys dosed with 1,2,3,5-TeCB. The fecal metabolites were identified in both groups. No metabolites were detected in the feces of monkeys dosed with 1,2,4,5-TeCB. While the fecal route represented the major route of excretion for 1,2,3,4-TeCB, the other two isomers were eliminated exclusively in the feces. The above data in the squirrel monkey are different from those obtained with the rat and the rabbit, and demonstrate the different metabolic pathways for the isomers.

  9. 40 CFR 721.10345 - 1,2-Benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...(methylcyclohexyl) ester. 721.10345 Section 721.10345 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Specific Chemical Substances § 721.10345 1,2-Benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester. (a... 1,2-benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester (PMN P-05-110; CAS No. 27987-25-3)...

  10. 40 CFR 721.10345 - 1,2-Benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...(methylcyclohexyl) ester. 721.10345 Section 721.10345 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Specific Chemical Substances § 721.10345 1,2-Benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester. (a... 1,2-benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester (PMN P-05-110; CAS No. 27987-25-3)...

  11. 40 CFR 721.10345 - 1,2-Benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...(methylcyclohexyl) ester. 721.10345 Section 721.10345 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Specific Chemical Substances § 721.10345 1,2-Benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester. (a... 1,2-benzenedicarboxylic acid, 1,2-bis(methylcyclohexyl) ester (PMN P-05-110; CAS No. 27987-25-3)...

  12. Emissions in potassium vapour under 4S1/2-7S1/2 two-photon nsec excitation

    NASA Astrophysics Data System (ADS)

    Pentaris, D.; Chatzikyriakos, G.; Armyras, A.; Efthimiopoulos, T.

    2010-11-01

    The two-photon excitation of 4S1/2-7S1/2 transition of potassium atoms is studied. Several coherent emissions and processes are possible, such as parametric four-wave (PFWM), parametric six-wave (PSWM) mixing and competition with the stimulated hyper Raman (SHRS) and the amplified spontaneous emission (ASE). The radiations at the transitions 6P3/2,1/2-4S1/2, 6S1/2-4P3/2,1/2 and 5P3/2,1/2-4S1/2 are emitted only in the forward direction (indicating a parametric process), while the radiation at the transition 4P3/2,1/2-4S1/2 is emitted in the forward and in the backward direction, indicating an ASE process.

  13. The Central Logic Board for the KM3NeT detector: Design and production

    NASA Astrophysics Data System (ADS)

    Musico, P.

    2016-07-01

    The KM3NeT deep sea neutrino observatory will include a very large number of multi-Photomultiplier (PMT) optical modules (DOM) to detect the Cherenkov light generated by secondary particles produced in neutrino interactions. The Central Logic Board (CLB) has been developed to acquire timing and amplitude information from the PMT signals, implementing time-to-digital conversion (TDC) with time over threshold (TOT) technique. The board is also used to configure all the DOM subsystems, to assist in the DOM position and orientation, calibration and to monitor temperature and humidity in the DOM itself. All the collected data are transmitted to shore using a wide-bandwidth optical network. Moreover, through the optical network, all the DOMs are kept synchronized in time within 1 ns precision using the White Rabbit (WR) Precision Time Protocol (PTP) over an Ethernet connection. A large Field Programmable Gate Array (FPGA) has been adopted to implement all the specifications witht the requested performances. The CLB will be also used in the base container of the detection unit (DU) to set-up and monitor all the requested functionalities: in this scenario a dedicated firmware and software will be deployed on board. The design has been started in early 2013 and several prototypes have been developed. After deep test carried on in different EU laboratories, the final mass production batch of 600 boards has been ordered and built: all the CLB are now ready for integration in the DOMs and base containers. The first two KM3NeT DU will be deployed in summer 2015 and all other units are in advanced stage of integration.

  14. Developing Knowledge Management (KM): Contributions by Organizational Learning and Total Quality Management (TQM)

    ERIC Educational Resources Information Center

    Hung, Richard Yu-Yuan; Lien, Bella Ya-Hui

    2005-01-01

    Knowledge management is an integral business function for many organizations to manage intellectual resources effectively. From a resource-based perspective, organizational learning and TQM are antecedents that are closely related to KM. The purposes of this study were to explain the contents of KM, and explore the relationship between KM-related…

  15. Completion of compilation of the 1:2,000,000-scale topographic map series of Mars

    NASA Astrophysics Data System (ADS)

    Wu, Sherman S. C.; Jordan, Raymond; Garcia, Patricia A.; Ablin, Karyn K.

    1991-06-01

    Using special photogrammetric techniques, Mars' topography is being systematically mapped at a scale of 1:2,000,000 from high-altitude Viking Orbiter images. Of the 140 maps in the series, 120 have previously been compiled on the AS-11AM analytical stereoplotters. In fiscal year 1991, the remaining 20 maps will be compiled (most of these are between +/- 30 degrees latitude and the poles). Elevations on the maps are related to the Mars topographic datum. The Mars planetwide control net is used for the control of compilation. The maps have a contour interval of 1 km and a vertical precision of +/- 1 km; thus, they are more detailed than previous maps.

  16. Completion of compilation of the 1:2,000,000-scale topographic map series of Mars

    NASA Technical Reports Server (NTRS)

    Wu, Sherman S. C.; Jordan, Raymond; Garcia, Patricia A.; Ablin, Karyn K.

    1991-01-01

    Using special photogrammetric techniques, Mars' topography is being systematically mapped at a scale of 1:2,000,000 from high-altitude Viking Orbiter images. Of the 140 maps in the series, 120 have previously been compiled on the AS-11AM analytical stereoplotters. In fiscal year 1991, the remaining 20 maps will be compiled (most of these are between +/- 30 degrees latitude and the poles). Elevations on the maps are related to the Mars topographic datum. The Mars planetwide control net is used for the control of compilation. The maps have a contour interval of 1 km and a vertical precision of +/- 1 km; thus, they are more detailed than previous maps.

  17. Resistance integrons: class 1, 2 and 3 integrons.

    PubMed

    Deng, Yang; Bao, Xuerui; Ji, Lili; Chen, Lei; Liu, Junyan; Miao, Jian; Chen, Dingqiang; Bian, Huawei; Li, Yanmei; Yu, Guangchao

    2015-10-20

    As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and reported to widely spread and extended to a large variety of microorganisms. In China, as one of the currently worst areas for antibiotics abuse, the annual prescription of antibiotics, including both clinical and veterinary treatment, has approaching 140 gram per person and been roughly estimated to be 10 times higher than that in the United Kingdom, which is considered to be a potential area for the emergence of "Super Bugs". Based on the integrons surveillance in Guangzhou, China in the past decade, this review thus aimed at summarizing the role of integrons in the perspective of both clinical setting and environment, with the focus on the occurrence and prevalence of class 1, 2 and 3 integrons.

  18. Underwater acoustic positioning system for the SMO and KM3NeT - Italia projects

    SciTech Connect

    Viola, S.; Barbagallo, G.; Cacopardo, G.; Calí, C.; Cocimano, R.; Coniglione, R.; Costa, M.; Cuttone, G.; D'Amato, C.; D'Amato, V.; D'Amico, A.; De Luca, V.; Del Tevere, F.; Distefano, C.; Ferrera, F.; Gmerk, A.; Grasso, R.; Imbesi, M.; Larosa, G.; Lattuada, D.; and others

    2014-11-18

    In the underwater neutrino telescopes, the positions of the Cherenkov light sensors and their movements must be known with an accuracy of few tens of centimetres. In this work, the activities of the SMO and KM3NeT-Italia teams for the development of an acoustic positioning system for KM3NeT-Italia project are presented. The KM3NeT-Italia project foresees the construction, within two years, of 8 towers in the view of the several km{sup 3}-scale neutrino telescope KM3NeT.

  19. Vibrational analysis of 1,2-dichloro-2-methylpropane and 1,2-dibromo-2-methylpropane

    NASA Astrophysics Data System (ADS)

    Crowder, G. A.; Richardson, Mary Townsend

    1982-02-01

    Liquid-state IR and Raman spectra and solid-state IR spectra have been obtained for 1,2-dichloro-2-methylpropane and l,2-dibromo-2-methylpropane. Carbon-halogen stretching bands are observed in the liquid-state spectrum of the dichloro compound at 751, 725, 624 and 574 cm -1 and at 677, 640, 551 and 507 cm -1 in the liquid-state spectrum of the dibromo compound. Both compounds exist as P CTt HHH and P XT XHH conformations in the liquid, but only the P XT XHH conformer is present for each in the crystalline solid. Further Interpretation of the spectra was aided by normal coordinate calculations.

  20. 26 CFR 1.1-2 - Limitation on tax.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Limitation on tax. 1.1-2 Section 1.1-2 Internal... Surtaxes § 1.1-2 Limitation on tax. (a) Taxable years ending before January 1, 1971. For taxable years ending before January 1, 1971, the tax imposed by section 1 (whether by subsection (a) or subsection...

  1. 26 CFR 1.1-2 - Limitation on tax.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Limitation on tax. 1.1-2 Section 1.1-2 Internal... Surtaxes § 1.1-2 Limitation on tax. (a) Taxable years ending before January 1, 1971. For taxable years ending before January 1, 1971, the tax imposed by section 1 (whether by subsection (a) or subsection...

  2. 26 CFR 1.1-2 - Limitation on tax.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Limitation on tax. 1.1-2 Section 1.1-2 Internal... Surtaxes § 1.1-2 Limitation on tax. (a) Taxable years ending before January 1, 1971. For taxable years ending before January 1, 1971, the tax imposed by section 1 (whether by subsection (a) or subsection...

  3. 43 CFR § 2812.1-2 - Contents.

    Code of Federal Regulations, 2012 CFR

    2015-10-01

    ... 43 Public Lands: Interior 2 2015-10-01 2015-10-01 false Contents. § 2812.1-2 Section § 2812.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT... Coos Bay Revested Lands § 2812.1-2 Contents. (a) An individual applicant and each member of...

  4. 49 CFR 1.2 - Organization of the Department.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Organization of the Department. 1.2 Section 1.2 Transportation Office of the Secretary of Transportation ORGANIZATION AND DELEGATION OF POWERS AND DUTIES General § 1.2 Organization of the Department. (a) The Secretary of Transportation is the head of the Department. (b) The Department comprises...

  5. 43 CFR 3473.1-2 - Where submitted.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Land Management State office having jurisdiction over the lands (43 CFR subpart 1821). (2) All second... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Where submitted. 3473.1-2 Section 3473.1-2..., Rentals, and Royalties § 3473.1-2 Where submitted. (a)(1) All first-year rentals and the...

  6. 43 CFR 3473.1-2 - Where submitted.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Land Management State office having jurisdiction over the lands (43 CFR subpart 1821). (2) All second... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Where submitted. 3473.1-2 Section 3473.1-2..., Rentals, and Royalties § 3473.1-2 Where submitted. (a)(1) All first-year rentals and the...

  7. 43 CFR 3473.1-2 - Where submitted.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Land Management State office having jurisdiction over the lands (43 CFR subpart 1821). (2) All second... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Where submitted. 3473.1-2 Section 3473.1-2..., Rentals, and Royalties § 3473.1-2 Where submitted. (a)(1) All first-year rentals and the...

  8. 43 CFR 3473.1-2 - Where submitted.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Land Management State office having jurisdiction over the lands (43 CFR subpart 1821). (2) All second... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Where submitted. 3473.1-2 Section 3473.1-2..., Rentals, and Royalties § 3473.1-2 Where submitted. (a)(1) All first-year rentals and the...

  9. Positive effect of lower body compression garments on subsequent 40-kM cycling time trial performance.

    PubMed

    de Glanville, Kieran M; Hamlin, Michael J

    2012-02-01

    This study aimed to investigate the effect of wearing graduated compression garments during recovery on subsequent 40-km time trial performance. In a randomized single-blind crossover experiment, 14 trained multisport male athletes (mean ± SD: age 33.8 ± 6.8 years, 40-km time 66:11 ± 2:10 minutes:seconds) were given a graduated full-leg-length compressive garment (76% Meryl Elastane, 24% Lycra) or a similar-looking noncompressive placebo garment (92% Polyester, 8% Spandex) to wear continuously for 24 hours after performing an initial 40-km time trial in their normal cycling attire. After the 24-hour recovery period, the compression (or placebo) garments were removed, and a second 40-km time trial was then completed to gauge the effect of each garment on subsequent performance. One week later, the groups were reversed and testing procedures repeated. The participant's hydration status, nutritional intake, and training were similar before each set of trials. Performance time in the second time trial was substantially improved with compression compared with placebo garments (1.2 ± 0.4%, mean ± 90% confidence interval). This improvement resulted in a substantially higher average power output after wearing the compression garment compared with that after wearing the placebo garment (3.3 ± 1.1%). Differences in oxygen cost and rating of perceived exertion between groups were trivial or unclear. The wearing of graduated compressive garments during recovery is likely to be worthwhile and unlikely to be harmful for well-trained endurance athletes.

  10. The Crust and Mantle Relationships Beneath Central and Southern Iberian Peninsula constrained by a 550 km long multiseismic transect

    NASA Astrophysics Data System (ADS)

    Ehsan, Siddique Akhtar; Carbonell, Ramon; Simancas, Jose Fernando; Martinez Poyatos, David; Azor, Antonio; Ayarza, Puy; Storti, Fabrizio

    2013-04-01

    A composite lithospheric cross section which is composed by data from controlled source multiseismic experiments strongly constrains the lithospheric structure of southwestern Iberia. The data includes coincident normal incidence and wide-angle profiles along an, approximately, 550 km long transect. This transect goes across, from North-to-South, the major tectonic zones that build up Southwestern part of the Iberian Peninsula (the Central Iberian Zone -CIZ-, the Ossa-Morena Zone -OMZ- and the South Portuguese Zone -SPZ-). The knowledge provided by these datasets constitutes the base to develop multidisciplinary models of the lithosphere. The multichannel deep seismic high resolution (60-90 fold) profiles, IBERSEIS & ALCUDIA were acquired in summer 2001 and 2007 are about 300 and 250 km long respectively. The transects image 20 s (TWTT), about 70 km depth. To address the crust and upper mantle structural relationships a reassessment of the normal incidence seismic reflection transect ALCUDIA has been carried out. We revised the key processing steps and applied advance analysis on the ALCUDIA transect with the aim to improve the signal to noise ratio especially in the deep parts and to produce a depth migrated image. The velocity model generated through wide-angle seismic survey (2003) was used to convert IBERSEIS time migrated stack image into depth. The new data processing flow provide better structural constraints on the shallow and deep structures as the current images reveal indentation features which strongly suggest horizontal tectonics. The ALCUDIA transect shows slightly less reflective upper crust about 13 km thick decoupled from the comparatively reflective lower crust. The reflectivity of the lower crust is continuous, high amplitude, horizontal and parallel though evidences of deformation are present as flat-ramp-flat geometry on the northeastern portion and a "Crocodile structure" wedging into the upper mantle on the southwestern portion of the ALCUDIA

  11. Reaction of pyrido(1,2-a)benzimidazole and tetrahydropyrido(1,2-a)benzimidazole with acetylenedicarboxylic ester

    SciTech Connect

    Prostakov, N.S.; Varlamov, A.V.; Shendrik, I.V.; Krapivko, A.P.; Golovtsov, N.I.

    1986-08-01

    Previously unknown polynuclear condensed systems with bridgehead nitrogen atoms have been obtained by treating acetylenedicarboxylic ester with pyrido(1,2-a)benzimidazole and tetrahydropyrido(1,2-a)benzimidazole.

  12. The effect of music on 10-km cycle time-trial performance.

    PubMed

    Hagen, Jana; Foster, Carl; Rodríguez-Marroyo, Jose; de Koning, Jos J; Mikat, Richard P; Hendrix, Charles R; Porcari, John P

    2013-01-01

    Music is widely used as an ergogenic aid in sport, but there is little evidence of its effectiveness during closed-loop athletic events. In order to determine the effectiveness of music as an ergogenic aid, well-trained and task-habituated cyclists performed 10-km cycle time trials either while listening to self-selected motivational music or with auditory input blocked. There were no statistically significant differences in performance time or physiological or psychological markers related to music (time-trial duration17.75 ± 2.10 vs 17.81 ± 2.06 min, mean power output 222 ± 66 vs 220 ± 65 W, peak heart rate184 ± 9 vs 183 ± 8 beats/min, peak blood lactate12.1 ± 2.6 vs 11.9 ± 2.1 mmol/L, and final rating of perceived exertion 8.4 ± 1.5 vs 8.5 ± 1.6). It is concluded that during exercise at competitive intensity, there is no meaningful effect of music on either performance or physiology.

  13. Observations of earthquake source parameters at 2 km depth in the Long Valley Caldera, eastern California

    USGS Publications Warehouse

    Prejean, Stephanie G.; Ellsworth, William L.

    2001-01-01

    To investigate seismic source parameter scaling and seismic efficiency in the Long Valley caldera, California, we measured source parameters for 41 earthquakes (M 0.5 to M 5) recorded at 2 km depth in the Long Valley Exploratory Well. Borehole recordings provide a wide frequency bandwidth, typically 1 to 200–300 Hz, and greatly reduce seismic noise and path effects compared to surface recordings. We calculated source parameters in both the time and frequency domains for P and S waves. At frequencies above the corner frequency, spectra decay faster than ω3, indicating that attenuation plays an important role in shaping the spectra (path averaged Qp = 100–400, Qs = 200–800). Source parameters are corrected for attenuation and radiation pattern. Both static stress drops and apparent stresses range from approximately 0.01 to 30 MPa. Although static stress drops do not vary with seismic moment for these data, our analyses are consistent with apparent stress increasing with increasing moment. To estimate tectonic driving stress and seismic efficiencies in the region, we combined source parameter measurements with knowledge of the stress field and a Coulomb failure criterion to infer a driving stress of 40–70 MPa. Subsequent seismic efficiencies are consistent with McGarr's (1999) hypothesis of a maximum seismic efficiency of 6%.

  14. On the penetration of the 660 km phase change by mantle downflows

    NASA Technical Reports Server (NTRS)

    Bercovici, David; Schubert, Gerald; Tackley, Paul J.

    1993-01-01

    We present a simple analytic model of the interaction of cold convective downwelling currents with an endothermic phase change. The model describes the ponding and lateral spreading of downflows along the phase transition interface. A simple comparison of the vertical forces on the ponding material provides a necessary condition for a downflow to penetrate the phase boundary. This condition is fundamentally dependent on the geometry of the downflow. For planar downwellings, the model predicts a minimum ponding time before the structure can penetrate the phase boundary. For columnar (axisymmetric) downflows, there is no minimum time of spreading required before penetration can proceed. The model thus provides an explanation for the observation that in numerical models of three-dimensional convection with an endothermic phase change, cylindrical downflows penetrate the phase interface while planar ones do not. Since descending slabs in the Earth's mantle display a wide spectrum of geometries between planar and cylindrical (given various trench curvatures, as well as intersections of two or more subduction zones), this phenomenon may explain, in part, why some slabs appear to extend into the lower mantle while others are deflected at the 660 km discontinuity.

  15. The effect of music on 10-km cycle time-trial performance.

    PubMed

    Hagen, Jana; Foster, Carl; Rodríguez-Marroyo, Jose; de Koning, Jos J; Mikat, Richard P; Hendrix, Charles R; Porcari, John P

    2013-01-01

    Music is widely used as an ergogenic aid in sport, but there is little evidence of its effectiveness during closed-loop athletic events. In order to determine the effectiveness of music as an ergogenic aid, well-trained and task-habituated cyclists performed 10-km cycle time trials either while listening to self-selected motivational music or with auditory input blocked. There were no statistically significant differences in performance time or physiological or psychological markers related to music (time-trial duration17.75 ± 2.10 vs 17.81 ± 2.06 min, mean power output 222 ± 66 vs 220 ± 65 W, peak heart rate184 ± 9 vs 183 ± 8 beats/min, peak blood lactate12.1 ± 2.6 vs 11.9 ± 2.1 mmol/L, and final rating of perceived exertion 8.4 ± 1.5 vs 8.5 ± 1.6). It is concluded that during exercise at competitive intensity, there is no meaningful effect of music on either performance or physiology. PMID:22868289

  16. First principles prediction of a morphotropic phase boundary in the Bi(Zn1/2Ti1/2)O3-(Bi1/2Sr1/2)(Zn1/2Nb1/2)O3 alloy

    SciTech Connect

    Cooper, Valentino R; Henry, Asegun S; Takagi, Shigeyuki M; Singh, David J

    2011-01-01

    The magnitude and direction of polarization within alloys of the tetragonally distorted Bi(Zn1/2Ti1/2)O3 (BZT) and the rhombohedrally oriented Bi1/2Sr1/2Zn1/2Nb1/2O3 (BSZN) are explored using density functional theory. For compositions with 50% of BZT, we find that the polarization points mainly along the [001] direction. Conversely, for low concentrations of BZT the polarization is rhombohedrally oriented. Based on these results we propose a phase diagram with a possible monoclinc phase between 25% and 50 % BZT where this material may have a useful piezoelectric response.

  17. Effects of training and anthropometric factors on marathon and 100 km ultramarathon race performance

    PubMed Central

    Tanda, Giovanni; Knechtle, Beat

    2015-01-01

    Background Marathon (42 km) and 100 km ultramarathon races are increasing in popularity. The aim of the present study was to investigate the potential associations of anthropometric and training variables with performance in these long-distance running competitions. Methods Training and anthropometric data from a large cohort of marathoners and 100 km ultramarathoners provided the basis of this work. Correlations between training and anthropometric indices of subjects and race performance were assessed using bivariate and multiple regression analyses. Results A combination of volume and intensity in training was found to be suitable for prediction of marathon and 100 km ultramarathon race pace. The relative role played by these two variables was different, in that training volume was more important than training pace for the prediction of 100 km ultramarathon performance, while the opposite was found for marathon performance. Anthropometric characteristics in terms of body fat percentage negatively affected 42 km and 100 km race performance. However, when this factor was relatively low (ie, less than 15% body fat), the performance of 42 km and 100 km races could be predicted solely on the basis of training indices. Conclusion Mean weekly training distance run and mean training pace were key predictor variables for both marathon and 100 km ultramarathon race performance. Predictive correlations for race performance are provided for runners with a relatively low body fat percentage. PMID:25995653

  18. Neutrophil activation induced by the lectin KM+ involves binding to CXCR2.

    PubMed

    Pereira-da-Silva, Gabriela; Moreno, Andréa N; Marques, Fabiana; Oliver, Constance; Jamur, Maria Célia; Panunto-Castelo, Ademilson; Roque-Barreira, Maria Cristina

    2006-01-01

    The lectin KM+ from Artocarpus integrifolia, also known as artocarpin, induces neutrophil migration by haptotaxis. The interactions of KM+ with both neutrophils and the extracellular matrix depend on the lectin's ability to recognize mannose-containing glycans. In the present study, we characterized the binding of KM+ to human neutrophils and the responses stimulated by this binding. Exposure to KM+ results in cell polarization, formation of a lamellipodium, and induction of deep ruffles on the cell surface. By fluorescence microscopy, we observed that KM+ is distributed homogeneously over the cell surface. KM+/ligand complexes are rapidly internalized, reaching maximum intracellular concentrations at 120 min, and decreasing thereafter. Furthermore, KM+ binding to the surface of human neutrophils is inhibited by the specific sugars, d-mannose or mannotriose. KM+-induced neutrophil migration is inhibited by pertussis toxin as well as by inhibition of CXCR2 activity. These results suggest that the KM+ ligand on the neutrophil surface is a G protein-coupled receptor (GPCR). The results also suggest that neutrophil migration induced by KM+ involves binding to CXCR2.

  19. ERF1_2 -- Enhanced River Reach File 2.0

    USGS Publications Warehouse

    Nolan, Jacqueline V.; Brakebill, John W.; Alexander, Richard B.; Schwarz, Gregory E.

    2003-01-01

    The digital segmented network based on watershed boundaries, ERF1_2, includes enhancements to the U.S. Environmental Protection Agency's River Reach File 1 (RF1) (USEPA, 1996; DeWald and others, 1985) to support national and regional-scale surface water-quality modeling. Alexander and others (1999) developed ERF1, which assessed the hydrologic integrity of the digital reach traces and calculated the mean water time-of-travel in river reaches and reservoirs. ERF1_2 serves as the foundation for SPARROW (Spatially Referenced Regressions (of nutrient transport) on Watershed) modeling. Within the context of a Geographic Information System, SPARROW estimates the proportion of watersheds in the conterminous U.S. with outflow concentrations of several nutrients, including total nitrogen and total phosphorus, (Smith, R.A., Schwarz, G.E., and Alexander, R.B., 1997). This version of the network expands on ERF1 (Version 1.2; Alexander, et al., 1999) and includes the incremental and total drainage area derived from 1-kilometer (km) elevation data for North America. Previous estimates of the water time-of-travel were recomputed for reaches with water-quality monitoring sites that included two reaches. The mean flow and velocity estimates for these split reaches are based on previous estimation methods (Alexander et al., 1999) and are unchanged in ERF1_2. Drainage area calculations provide data used to estimate the contribution of a given nutrient to the outflow. Data estimates depend on the accuracy of node connectivity. Reaches split at water-quality or pesticide-monitoring sites indicate the source point for estimating the contribution and transport of nutrients and their loads throughout the watersheds. The ERF1_2 coverage extends the earlier drainage area founded on the 1-kilometer data for North America (Verdin, 1996; Verdin and Jenson, 1996). A 1-kilometer raster grid of ERF1_2 projected to Lambert Azimuthal Equal Area, NAD 27 Datum (Snyder, 1987), was merged with the

  20. A 16-year time series of 1 km AVHRR satellite data of the conterminous United States and Alaska

    USGS Publications Warehouse

    Eldenshink, J.

    2006-01-01

    The U.S. Geological Survey (USGS) has developed a 16-year time series of vegetation condition information for the conterminous United States and, Alaska using 1 km Advanced Very High Resolution Radiometer (AVHRR) data. The AVHRR data have been processed using consistent methods that account for radiometric variability due to calibration uncertainty, the effects of the atmosphere on surface radiometric measurements obtained from wide field-of-view observations, and the geometric registration accuracy. The conterminous United States and Alaska data sets have an atmospheric correction for water vapor, ozone, and Rayleigh scattering and include a cloud mask derived using the Clouds from AVHRR (CLAVR) algorithm. In comparison with other AVHRR time series data sets, the conterminous United States and Alaska data are processed using similar techniques. The primary difference is that the conterminous United States and Alaska data are at 1 km resolution, while others are at 8 km resolution. The time series consists of weekly and biweekly maximum normalized difference vegetation index (NDVI) composites. ?? 2006 American Society for Photogrammetry and Remote Sensing.

  1. Demonstration of Redox Potential of Metschnikowia koreensis for Stereoinversion of Secondary Alcohols/1,2-Diols

    PubMed Central

    Meena, Vachan Singh; Banoth, Linga; Banerjee, U. C.

    2014-01-01

    The present work reports the Metschnikowia koreensis-catalyzed one-pot deracemization of secondary alcohols/1,2-diols and their derivatives with in vivo cofactor regeneration. Reaction is stereoselective and proceeds with sequential oxidation of (R)-secondary alcohols to the corresponding ketones and the reduction of the ketones to (S)-secondary alcohols. Method is applicable to a repertoire of racemic aryl secondary alcohols and 1,2-diols establishing a wide range of substrate specificity of M. koreensis. This ecofriendly method afforded the product in high yield (88%) and excellent optical purity (>98% ee), minimizing the requirement of multistep reaction and expensive cofactor. PMID:24592389

  2. Sub-km HIMU-type Enriched Mantle at a Mid-ocean Ridge Far From a Plume: Endeavour, JdFR

    NASA Astrophysics Data System (ADS)

    Gill, J. B.; Michael, P. J.; Dreyer, B. M.; Clague, D. A.; Ramos, F. C.

    2015-12-01

    The Endeavour segment of the Juan de Fuca Ridge is characterized by abundant enriched (E) MORB since the currently inflated axial ridge formed <105 years ago, and by the full range of depleted (D) to E-MORB during the last 2300 years in the km-wide axial graben. Two different styles of enrichment of moderately incompatible elements are present. The first characterized basalts across the ~5 km-wide ridge from >10,000 to ~4000 years ago, whereas the second characterizes more recent basalts erupted in the axial graben. We attribute the first to a higher proportion of pyroxenite to enriched peridotite in the mantle source during ridge inflation. The more recent style reflects the reduced role of pyroxenite after the axial graben formed. The enriched component for both styles is a HIMU-type because it has low 87Sr/86Sr and 176Hf/177Hf relative to 143Nd/144Nd, lower 3He/4He (~8.1 RA) than in the more depleted basalts, shallow slopes on Pb isotope diagrams, and high Nb/LREE ratios. It is regionally widespread and shared with the West Valley and Explorer segments to the north. At least 14 different samplings of mantle components occurred within <1 km of ridge length and width during a time when <1 km of upwelling occurred, indicating that the scale of mantle heterogeneity is <1 km in this setting that is far from a plume.

  3. Experimentally driven atomistic model of 1,2 polybutadiene

    NASA Astrophysics Data System (ADS)

    Gkourmpis, Thomas; Mitchell, Geoffrey R.

    2014-02-01

    We present an efficient method of combining wide angle neutron scattering data with detailed atomistic models, allowing us to perform a quantitative and qualitative mapping of the organisation of the chain conformation in both glass and liquid phases. The structural refinement method presented in this work is based on the exploitation of the intrachain features of the diffraction pattern and its intimate linkage with atomistic models by the use of internal coordinates for bond lengths, valence angles, and torsion rotations. Atomic connectivity is defined through these coordinates that are in turn assigned by pre-defined probability distributions, thus allowing for the models in question to be built stochastically. Incremental variation of these coordinates allows for the construction of models that minimise the differences between the observed and calculated structure factors. We present a series of neutron scattering data of 1,2 polybutadiene at the region 120-400 K. Analysis of the experimental data yields bond lengths for CC and C  C of 1.54 Å and 1.35 Å, respectively. Valence angles of the backbone were found to be at 112° and the torsion distributions are characterised by five rotational states, a three-fold trans-skew± for the backbone and gauche± for the vinyl group. Rotational states of the vinyl group were found to be equally populated, indicating a largely atactic chan. The two backbone torsion angles exhibit different behaviour with respect to temperature of their trans population, with one of them adopting an almost all trans sequence. Consequently, the resulting configuration leads to a rather persistent chain, something indicated by the value of the characteristic ratio extrapolated from the model. We compare our results with theoretical predictions, computer simulations, RIS models and previously reported experimental results.

  4. Experimentally driven atomistic model of 1,2 polybutadiene

    SciTech Connect

    Gkourmpis, Thomas; Mitchell, Geoffrey R.

    2014-02-07

    We present an efficient method of combining wide angle neutron scattering data with detailed atomistic models, allowing us to perform a quantitative and qualitative mapping of the organisation of the chain conformation in both glass and liquid phases. The structural refinement method presented in this work is based on the exploitation of the intrachain features of the diffraction pattern and its intimate linkage with atomistic models by the use of internal coordinates for bond lengths, valence angles, and torsion rotations. Atomic connectivity is defined through these coordinates that are in turn assigned by pre-defined probability distributions, thus allowing for the models in question to be built stochastically. Incremental variation of these coordinates allows for the construction of models that minimise the differences between the observed and calculated structure factors. We present a series of neutron scattering data of 1,2 polybutadiene at the region 120–400 K. Analysis of the experimental data yields bond lengths for Cî—¸C and C î—» C of 1.54 Å and 1.35 Å, respectively. Valence angles of the backbone were found to be at 112° and the torsion distributions are characterised by five rotational states, a three-fold trans-skew± for the backbone and gauche± for the vinyl group. Rotational states of the vinyl group were found to be equally populated, indicating a largely atactic chan. The two backbone torsion angles exhibit different behaviour with respect to temperature of their trans population, with one of them adopting an almost all trans sequence. Consequently, the resulting configuration leads to a rather persistent chain, something indicated by the value of the characteristic ratio extrapolated from the model. We compare our results with theoretical predictions, computer simulations, RIS models and previously reported experimental results.

  5. MODIS 3 Km Aerosol Product: Applications over Land in an Urban/suburban Region

    NASA Technical Reports Server (NTRS)

    Munchak, L. A.; Levy, R. C.; Mattoo, S.; Remer, L. A.; Holben, B. N.; Schafer, J. S.; Hostetler, C. A.; Ferrare, R. A.

    2013-01-01

    MODerate resolution Imaging Spectroradiometer (MODIS) instruments aboard the Terra and Aqua satellites have provided a rich dataset of aerosol information at a 10 km spatial scale. Although originally intended for climate applications, the air quality community quickly became interested in using the MODIS aerosol data. However, 10 km resolution is not sufficient to resolve local scale aerosol features. With this in mind, MODIS Collection 6 is including a global aerosol product with a 3 km resolution. Here, we evaluate the 3 km product over the Baltimore/Washington D.C., USA, corridor during the summer of 2011, by comparing with spatially dense data collected as part of the DISCOVER-AQ campaign these data were measured by the NASA Langley Research Center airborne High Spectral Resolution Lidar (HSRL) and a network of 44 sun photometers (SP) spaced approximately 10 km apart. The HSRL instrument shows that AOD can vary by up to 0.2 within a single 10 km MODIS pixel, meaning that higher resolution satellite retrievals may help to characterize aerosol spatial distributions in this region. Different techniques for validating a high-resolution aerosol product against SP measurements are considered. Although the 10 km product is more statistically reliable than the 3 km product, the 3 km product still performs acceptably, with more than two-thirds of MODIS/SP collocations falling within the expected error envelope with high correlation (R > 0.90). The 3 km product can better resolve aerosol gradients and retrieve closer to clouds and shorelines than the 10 km product, but tends to show more significant noise especially in urban areas. This urban degradation is quantified using ancillary land cover data. Overall, we show that the MODIS 3 km product adds new information to the existing set of satellite derived aerosol products and validates well over the region, but due to noise and problems in urban areas, should be treated with some degree of caution.

  6. Cratering and penetration experiments in Teflon targets at velocities from 1 to 7 km/s

    NASA Technical Reports Server (NTRS)

    Hoerz, Friedrich; Bernhard, Ronald P.; Cintala, Mark J.; See, Thomas H.

    1995-01-01

    Approximately 20 sq m of protective thermal blankets, largely composed of Teflon, were retrieved from the Long Duration Exposure Facility (LDEF) after the spacecraft had spent approximately 5.7 years in space. Examination of these blankets revealed that they contained thousands of hypervelocity impact features ranging from micron-sized craters to penetration holes several millimeters in diameter. We conducted impact experiments in an effort to reproduce such features and to -- hopefully -- understand the relationships between projectile size and the resulting crater or penetration-hole diameter over a wide range of impact velocity. Such relationships are needed to derive the size- and mass-frequency distribution and flux of natural and man-made particles in low-Earth orbit. Powder propellant and light-gas guns were used to launch soda-lime glass spheres of 3.175 mm (1/8 inch) nominal diameter (Dp) into pure Teflon FEP targets at velocities ranging from 1 to 7 km/s. Target thickness (T) was varied over more than three orders of magnitude from infinite halfspace targets (Dp/T less than 0.1) to very thin films (Dp/T greater than 100). Cratering and penetration of massive Teflon targets is dominated by brittle failure and the development of extensive spall zones at the target's front and, if penetrated, the target's rear side. Mass removal by spallation at the back side of Teflon targets may be so severe that the absolute penetration-hole diameter (Dh) can become larger than that of a standard crater (Dc) at relative target thicknesses of Dp/T = 0.6-0.9. The crater diameter is infinite halfspace Teflon targets increases -- at otherwise constant impact conditions -- with encounter velocity by a factor of V0.44. In contrast, the penetration-hole size is very thin foils (Dp/T greater than 50) is essentially unaffected by impact velocity. Penetrations at target thicknesses intermediate to these extremes will scale with variable exponents of V. Our experimental matrix is

  7. Cratering and penetration experiments in teflon targets at velocities from 1 to 7 km/s

    NASA Technical Reports Server (NTRS)

    Horz, Friedrich; Cintala, Mark; Bernhard, Ronald P.; Cardenas, Frank; Davidson, William; Haynes, Gerald; See, Thomas H.; Winkler, Jerry; Knight, Jeffrey

    1994-01-01

    Approximately 20 sq m of protective thermal blankets, largely composed of Teflon, were retrieved from the Long Duration Exposure Facility after the spacecraft spent approximately 5.7 years in space. Examination of these blankets revealed that they contained thousands of hypervelocity impact features ranging from micron-sized craters to penetration holes several millimeters in diameter. We conducted impact experiments to reproduce such features and to understand the relationships between projectile size and the resulting crater or penetration hole diameter over a wide range of impact velocities. Such relationships are needed to derive the size and mass frequency distribution and flux of natural and man-made particles in low-earth orbit. Powder propellant and light-gas guns were used to launch soda-lime glass spheres into pure Teflon targets at velocities ranging from 1 to 7 km/s. Target thickness varied over more than three orders of magnitude from finite halfspace targets to very thin films. Cratering and penetration of massive Teflon targets is dominated by brittle failure and the development of extensive spall zones at the target's front and, if penetrated, the target's rear side. Mass removal by spallation at the back side of Teflon targets may be so severe that the absolute penetration hole diameter can become larger than that of a standard crater. The crater diameter in infinite halfspace Teflon targets increases, at otherwise constant impact conditions, with encounter velocity by a factor of V (exp 0.44). In contrast, the penetration hole size in very thin foils is essentially unaffected by impact velocity. Penetrations at target thicknesses intermediate to these extremes will scale with variable exponents of V. Our experimental matrix is sufficiently systematic and complete, up to 7 km/s, to make reasonable recommendations for velocity-scaling of Teflon craters and penetrations. We specifically suggest that cratering behavior and associated equations apply

  8. MODIS aerosol product at 3 km spatial resolution for urban and air quality studies

    NASA Astrophysics Data System (ADS)

    Mattoo, S.; Remer, L. A.; Levy, R. C.; Holben, B. N.; Smirnov, A.

    2008-12-01

    The MODerate resolution Imaging Spectroradiometer (MODIS) aboard the Terra and Aqua satellites has been producing an aerosol product since early 2000. The original product reports aerosol optical depth and a variety of other aerosol parameters at a spatial resolution of 10 km over both land and ocean. The 10 km product is actually constructed from 500 m pixels, which permits a strict selection process to choose the "best" or "cleanest" pixels in each 10 km square for use in the aerosol retrieval. Thus, the original 10 km product provides a useful product, accurate in many applications. However, the 10 km product can miss narrow aerosol plumes and the spatial variability associated with urban air pollution. The MODIS aerosol team will be introducing a finer resolution aerosol product over land regions in the next release of the product (Collection 6). The new product will be produced at 3 km resolution. It is based on the same procedures as the original product and benefits from the same spatial variability criteria for finding and masking cloudy pixels. The 3 km product does capture the higher spatial variability associated with individual aerosol plumes. However, it is noisier than the 10 km product. Both products will be available operationally in Collection 6. The new 3km product offers new synergistic possibilities with PM2.5 monitoring networks, AERONET and various air quality models such as CMAQ.

  9. Potential of KM3NeT to observe galactic neutrino point-like sources

    NASA Astrophysics Data System (ADS)

    Trovato, Agata

    2016-07-01

    KM3NeT (http://www.km3net.org">http://www.km3net.org) will be the next-generation cubic-kilometre-scale neutrino telescope to be installed in the depths of the Mediterranean Sea. This location will allow for surveying the Galactic Centre, most of the Galactic Plane as well as a large part of the sky. We report KM3NeT discovery potential for the SNR RXJ1713.7-3946 and the PWN Vela X and its sensitivity to point-like sources with an E-2 spectrum.

  10. Protective effect of kombucha mushroom (KM) tea on phenol-induced cytotoxicity in albino mice.

    PubMed

    Yapar, Kursad; Cavusoglu, Kultigin; Oruc, Ertan; Yalcin, Emine

    2010-09-01

    The present study was carried out to evaluate the protective role of kombucha mushroom (KM) tea on cytotoxicity induced by phenol (PHE) in mice. We used weight gain and micronucleus (MN) frequency as indicators of cytotoxicity and supported these parameters with pathological findings. The animals were randomly divided into seven groups: (Group I) only tap water (Group II) 1000 microl kg(-1) b. wt KM-tea, (Group III) 35 mg kg(-1) body wt. PHE (Group IV) 35 mg kg(-1) body wt. PHE + 250 microl kg(-1) b. wt KM-tea (Group V) 35 mg kg(-1) b. wt PHE + 500 microl kg(-1) b. wt KM-tea (Group VI) 35 mg kg(-1) b. wt PHE + 750 microl kg(-1) b. wt KM-tea, (Group VII) 35 mg kg(-1) b. wt PHE + 1000 microl kg(-1) b. wt KM-tea, for 20 consecutive days by oral gavage. The results indicated that all KM-tea supplemented mice showed a lower MN frequency than erythrocytes in only PHE-treated group. There was an observable regression on account of lesions in tissues of mice supplemented with different doses of KM-tea in histopathological observations. In conclusion, the KM-tea supplementation decreases cytotoxicity induced by PHE and its protective role is dose-dependent.

  11. Synthesis of Naphtho[1',2':4,5]imidazo[1,2-a]pyridines and Imidazo[5,1,2-cd]indolizines Through Pd-Catalyzed Cycloaromatization of 2-Phenylimidazo[1,2-a]pyridines with Alkynes.

    PubMed

    Li, Peiyuan; Zhang, Xinying; Fan, Xuesen

    2015-08-01

    In this paper, palladium-catalyzed oxidative cycloaromatization of 2-phenylimidazo[1,2-a]pyridine (PIP) with internal alkyne is studied. From this reaction, two classes of fused N-heterocycle, naphtho[1',2':4,5]imidazo[1,2-a]pyridine (NIP) and imidazo[5,1,2-cd]indolizine (IID), were formed through dehydrogenative coupling featured with cleavage of the C-H bonds located on different moiety of the PIP substrates. Moreover, when 5-methyl-2-phenylimidazo [1,2-a]pyridine or 2-mesitylimidazo[1,2-a]pyridine was used, either NIP or IID could be obtained as an exclusive product with good efficiency. Intriguingly, Pd(II) showed different action mode in promoting this reaction compared with Rh(III) and led to the formation of NIP with reversed regio-selectivity for the reaction of asymmetrical alkyne. PMID:26168267

  12. X-1-2 on Ramp with Boeing B-29

    NASA Technical Reports Server (NTRS)

    1949-01-01

    The Bell Aircraft Corporation X-1-2 sitting on the ramp at NACA High- Speed Flight Research Station with the Boeing B-29 launch ship behind. The B-29 was fondly referred to as 'Fertile Myrtle.' The painting near the nose depicts a stork carrying a bundle which is symbolic of the Mothership launching her babe (X-1-2). The pilot access door is open to the cockpit of the X-1-2 aircraft.

  13. Precision polarizability measurements of atomic cesium's 8 s 2S1 / 2 and 9 s 2S1 / 2 states

    NASA Astrophysics Data System (ADS)

    Weaver, Hannah; Kortyna, Andrew

    2013-05-01

    We report hyperfine-resolved scalar polarizabilities for cesium's 8 s 2S1 / 2 and 9 s 2S1 / 2 states using resonant two-photon spectroscopy. Two single-mode, external-cavity diode lasers drive the 6 s 2S1 / 2 --> 6 p 2P1 / 2 --> ns 2S1 / 2 transition (n = 8 or 9). Both laser beams are split and counter-propagate through an effusive beam and a vapor cell. An electric field applied across two parallel plates imposes Stark shifts on the ns 2S1 / 2 levels in the effusive beam. Electric-field strengths are measured in situ. The laser frequency is calibrated in the vapor cell using a phase modulation technique, with the modulation frequency referenced to the ground-state hyperfine splitting of atomic rubidium. Our measured 8 s 2S1 / 2 polarizability, 38370 +/- 380 a03, agrees with previous theory and experiments. Our measured 9 s 2S1 / 2 polarizability, 150700 +/- 1100 a03, agrees within two sigma of theory, but we are unaware of previous measurements. We also verify that these polarizabilities are independent of the hyperfine levels, placing upper limits on the differential polarizabilities of 200 +/- 260 a03 for the 8 s 2S1 / 2 state and 490 +/- 450 a03 for the 9 s 2S1 / 2 state. Supported by the National Science Foundation under Grant PHY-0653107.

  14. Determination of depolarization temperature of (Bi1/2Na1/2)TiO3-based lead-free piezoceramics

    NASA Astrophysics Data System (ADS)

    Anton, Eva-Maria; Jo, Wook; Damjanovic, Dragan; Rödel, Jürgen

    2011-11-01

    The depolarization temperature Td of piezoelectric materials is an important figure of merit for their application at elevated temperatures. Until now, there are several methods proposed in the literature to determine the depolarization temperature of piezoelectrics, which are based on different physical origins. Their validity and inter-correlation have not been clearly manifested. This paper applies the definition of depolarization temperature as the temperature of the steepest decrease of remanent polarization and evaluates currently used methods, both in terms of this definition and practical applicability. For the investigations, the lead-free piezoceramics (1-y)(Bi1/2Na1/2TiO3-xBi1/2K1/2TiO3)-yK0.5Na0.5NbO3 in a wide compositional range were chosen. Results were then compared to those for BaTiO3 and a commercial Pb(Zr,Ti)O3-based material as references. Thermally stimulated depolarization current and in situ temperature-dependent piezoelectric coefficient d33 are recommended to determine Td according to the proposed definition. Methods based on inflection point of the real part of permittivity or the peak in dielectric loss give consistently higher temperature values.

  15. Particle agglutination test "Serodia HIV-1/2" as a novel anti-HIV-1/2 screening test: comparative study on 3311 serum samples.

    PubMed

    Poljak, M; Zener, N; Seme, K; Kristancic, L

    1997-01-01

    Enzyme immunoassays are most widely used screening tests for antibodies to human immunodeficiency viruses (HIV). Nevertheless, the need of simpler, noninstrumented tests is evident in many parts of the world, where laboratory facilities and trained personnel are limited, and HIV incidence is high. A recently developed variant of gelatin-particle agglutination tests, Serodia HIV-1/2 (Fujirebio Inc., Tokyo, Japan), is one of such simple and noninstrumented tests. To evaluate its utility, 3311 serum samples (281 anti-HIV-1 positive, 8 anti-HIV-2 positive and 3022 anti-HIV-1/2 negative) obtained from 2632 individuals from Slovenia, other parts of former Yugoslavia and Senegal were investigated. No false-negative results and only one false-positive result were obtained during the procedures, giving overall sensitivity and specificity of the particle agglutination test of 100% and 99.97%, respectively. We have concluded that Serodia HIV-1/2 test is highly specific and sensitive for detection of anti-HIV-1/2 antibodies, suitable for small blood banks and for epidemiological surveys.

  16. Hayward Fault: A 50-km-long Locked Patch Regulates Its Large Earthquake Cycle (Invited)

    NASA Astrophysics Data System (ADS)

    Lienkaemper, J. J.; Simpson, R. W.; Williams, P. L.; McFarland, F. S.; Caskey, S. J.

    2010-12-01

    We have documented a chronology of 11 paleoearthquakes on the southern Hayward fault (HS) preceding the Mw6.8, 1868 earthquake. These large earthquakes were both regular and frequent, as indicated by a 0.40 coefficient of variation and mean recurrence interval (MRI) of 161 ± 65 yr (1σ of recurrence intervals). Furthermore, the Oxcal-modeled probability distribution for the average interval resembles a Gaussian rather than a more irregular Brownian passage time distribution. Our revised 3D-modeling of subsurface creep, using newly updated long-term creep rates, now suggests there is only one ~50-km-long locked patch (instead of two), confined laterally between two large patches of deep creep (≥9 km), with an extent consistent with evidence for the 1868 rupture. This locked patch and the fault’s lowest rates of surface creep are approximately centered on HS’s largest bend and a large gabbro body, particularly where the gabbro forms both east and west faces of the fault. We suggest that this locked patch serves as a mechanical capacitor, limiting earthquake size and frequency. The moment accumulation over 161 yr summed on all locked elements of the model reaches Mw6.79, but if half of the moment stored in the creeping elements were to fail dynamically, Mw could reach 6.91. The paleoearthquake histories for nearby faults of the San Francisco Bay region appear to indicate less regular and frequent earthquakes, possibly because most lack the high proportion (40-60%) of aseismic release found on the Hayward fault. The northernmost Hayward fault and Rodgers Creek fault (RCF) appear to rupture only half as frequently as the HS and are separated from the HS by a creep buffer and 5-km wide releasing bend respectively, both tending to limit through-going ruptures. The paleoseismic record allows multi-segment, Hayward fault-RCF ruptures, but does not require it. The 1868 HS rupture preceded the 1906 multi-segmented San Andreas fault (SAF) rupture, perhaps because the HS

  17. Catalytic hydrodechlorination of 1,2-dichloroethane using copper nanoparticles under reduction conditions of sodium borohydride.

    PubMed

    Huang, Chang-Chieh; Lo, Shang-Lien; Tsai, Shin-Mu; Lien, Hsing-Lung

    2011-09-01

    1,2-Dichloroethane (1,2-DCA) is a raw material used for the manufacture of vinyl chloride monomer (VCM) and therefore has very often been detected in the groundwater nearby the VCM manufacturing plant. Zero-valent iron (ZVI) is capable of degrading a wide array of highly chlorinated contaminants; however, the reactivity of ZVI towards 1,2-DCA is very low. In this study, zero-valent copper nanoparticles have been synthesized for effective dechlorination of 1,2-DCA under reduction conditions of sodium borohydride. Copper nanoparticles consisted of mainly metallic copper (Cu(0)) with small amounts of cuprous oxide (Cu(2)O). They have surface areas of about 19.0 m(2) g(-1) and an average diameter of 15 nm. Batch experiments were conducted to test the effectiveness of copper nanoparticles for 1,2-DCA degradation using sodium borohydride as electron donors where the ORP was measured as -1100 mV. More than 80% of 1,2-DCA (30 mg L(-1)) was rapidly degraded within 2 h in the presence of both copper nanoparticles (2.5 g L(-1)) and borohydride (25 mM). No reduction of 1,2-DCA was observed when the system contained either copper nanoparticles alone or borohydride alone. The degradation intermediates included ethane and ethylene accounting for 79% and ∼1.5% of the 1,2-DCA lost, respectively. Potential environmental applications can be achieved by immobilizing copper nanoparticles onto the surface of reducing metals to form a reactive bimetallic structure.

  18. Improved sparse reconstruction for fluorescence molecular tomography with L1/2 regularization

    PubMed Central

    Guo, Hongbo; Yu, Jingjing; He, Xiaowei; Hou, Yuqing; Dong, Fang; Zhang, Shuling

    2015-01-01

    Fluorescence molecular tomography (FMT) is a promising imaging technique that allows in vivo visualization of molecular-level events associated with disease progression and treatment response. Accurate and efficient 3D reconstruction algorithms will facilitate the wide-use of FMT in preclinical research. Here, we utilize L1/2-norm regularization for improving FMT reconstruction. To efficiently solve the nonconvex L1/2-norm penalized problem, we transform it into a weighted L1-norm minimization problem and employ a homotopy-based iterative reweighting algorithm to recover small fluorescent targets. Both simulations on heterogeneous mouse model and in vivo experiments demonstrated that the proposed L1/2-norm method outperformed the comparative L1-norm reconstruction methods in terms of location accuracy, spatial resolution and quantitation of fluorescent yield. Furthermore, simulation analysis showed the robustness of the proposed method, under different levels of measurement noise and number of excitation sources. PMID:26137370

  19. Changes in Body Mass, Hydration and Electrolytes Following a 161-km Endurance Race

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Purpose: To examine electrolyte concentrations and changes in body mass and total body water (TBW) during a 161-km ultra-marathon, and relate these to finish time and incidence of hyponatremia. Methods: Subjects were recruited from the 161-km 2008 Rio Del Lago Endurance Race. Body mass, TBW, and s...

  20. Draft Genome Sequence of the Bordetella bronchiseptica Swine Isolate KM22.

    PubMed

    Nicholson, Tracy L; Shore, Sarah M; Bayles, Darrell O; Register, Karen B; Kingsley, Robert A

    2014-01-01

    Bordetella bronchiseptica swine isolate KM22 has been used in experimental infections of swine as a model of clinical B. bronchiseptica infections within swine herds and to study host-to-host transmission. Here we report the draft genome sequence of KM22. PMID:25013141

  1. Acute prior heavy strength exercise bouts improve the 20-km cycling time trial performance.

    PubMed

    Silva, Renato A S; Silva-Júnior, Fernando L; Pinheiro, Fabiano A; Souza, Patrícia F M; Boullosa, Daniel A; Pires, Flávio O

    2014-09-01

    This study verified if a prior 5 repetition maximum (5RM) strength exercise would improve the cycling performance during a 20-km cycling time trial (TT20km). After determination of the 5RM leg press exercise load, 11 trained cyclists performed a TT20km in a control condition and 10-minute after 4 sets of 5RM strength exercise bouts (potentiation condition). Oxygen uptake, blood lactate concentration, ratings of perceived exertion (RPE), and power output data were recorded during the TT20km. Cycling economy index was assessed before the TT20km, and pacing strategy was analyzed assuming a "J-shaped" power output distribution profile. Results were a 6.1% reduction (p ≤ 0.05) in the time to complete the TT20km, a greater cycling economy (p < 0.01), and power output in the first 10% of the TT20km (i.e., trend; p = 0.06) in the potentiation condition. However, no differences were observed in pacing strategy, physiological parameters, and RPE between the conditions. These results suggest that 5RM strength exercise bouts improve the performance in a subsequent TT20km.

  2. A Co-Creation Blended KM Model for Cultivating Critical-Thinking Skills

    ERIC Educational Resources Information Center

    Yeh, Yu-chu

    2012-01-01

    Both critical thinking (CT) and knowledge management (KM) skills are necessary elements for a university student's success. Therefore, this study developed a co-creation blended KM model to cultivate university students' CT skills and to explore the underlying mechanisms for achieving success. Thirty-one university students participated in this…

  3. Draft genome sequence of the Bordetella bronchiseptica swine isolate KM22

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Bordetella bronchiseptica swine isolate KM22 has been used in experimental infections of swine as a model of clinical B. bronchiseptica infections within swine herds and to study host-to-host transmission. Here we report the draft genome sequence of KM22....

  4. Draft Genome Sequence of the Bordetella bronchiseptica Swine Isolate KM22.

    PubMed

    Nicholson, Tracy L; Shore, Sarah M; Bayles, Darrell O; Register, Karen B; Kingsley, Robert A

    2014-01-01

    Bordetella bronchiseptica swine isolate KM22 has been used in experimental infections of swine as a model of clinical B. bronchiseptica infections within swine herds and to study host-to-host transmission. Here we report the draft genome sequence of KM22.

  5. Wide Bandgap Extrinsic Photoconductive Switches

    NASA Astrophysics Data System (ADS)

    Sullivan, James Stephen

    material with much higher quantum efficiency and carrier recombination time of 0.9 to 1.0 ns. The iron compensated 2H-GaN did not perform well as an extrinsic photoconductive switch. The density of carriers generated at 1064 nm was, low indicating that there were very few electrons trapped in the iron acceptor level located at 0.5 - 0.6 eV below the conduction band. Carrier generation at 532 nm was dominated by two photon absorption resulting in the switch conductance increasing as the square of applied optical intensity. A minimum switch resistance of 0.8 ohms was calculated for the 400 nm thick, 1.2 by 1.2 cm, 2H-GaN switch for an applied optical intensity of 41.25 MW/cm2. An optical intensity of ˜ 70 MW/cm2 at 532 nm would be required to achieve a 0.8 ohm on resistance for a 1 mm thick, 1 cm2, 2H-GaN switch.

  6. 43 CFR 3101.1-2 - Surface use rights.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Surface use rights. 3101.1-2 Section 3101... § 3101.1-2 Surface use rights. A lessee shall have the right to use so much of the leased lands as is... operations, and specification of interim and final reclamation measures. At a minimum, measures shall...

  7. 43 CFR 3101.1-2 - Surface use rights.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Surface use rights. 3101.1-2 Section 3101... § 3101.1-2 Surface use rights. A lessee shall have the right to use so much of the leased lands as is... operations, and specification of interim and final reclamation measures. At a minimum, measures shall...

  8. 43 CFR 3101.1-2 - Surface use rights.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Surface use rights. 3101.1-2 Section 3101... § 3101.1-2 Surface use rights. A lessee shall have the right to use so much of the leased lands as is... operations, and specification of interim and final reclamation measures. At a minimum, measures shall...

  9. 50 CFR Figures 1-2 to Part 223 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false 1 Figures 1-2 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES Figures 1-2 to Part 223...

  10. 50 CFR Figures 1-2 to Part 223 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false 1 Figures 1-2 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES Figures 1-2 to Part 223...

  11. 41 CFR 60-1.2 - Administrative responsibility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Administrative responsibility. 60-1.2 Section 60-1.2 Public Contracts and Property Management Other Provisions Relating to... OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS Preliminary Matters; Equal...

  12. 41 CFR 60-1.2 - Administrative responsibility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Administrative responsibility. 60-1.2 Section 60-1.2 Public Contracts and Property Management Other Provisions Relating to... OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS Preliminary Matters; Equal...

  13. 41 CFR 60-1.2 - Administrative responsibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Administrative responsibility. 60-1.2 Section 60-1.2 Public Contracts and Property Management Other Provisions Relating to... OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS Preliminary Matters; Equal...

  14. 41 CFR 60-1.2 - Administrative responsibility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Administrative responsibility. 60-1.2 Section 60-1.2 Public Contracts and Property Management Other Provisions Relating to... OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS Preliminary Matters; Equal...

  15. 41 CFR 60-1.2 - Administrative responsibility.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Administrative responsibility. 60-1.2 Section 60-1.2 Public Contracts and Property Management Other Provisions Relating to... OF LABOR 1-OBLIGATIONS OF CONTRACTORS AND SUBCONTRACTORS Preliminary Matters; Equal...

  16. 77 FR 30407 - 1,2-Ethanediamine, N

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... petition to EPA under the Federal Food, Drug, and Cosmetic Act (FFDCA), requesting an exemption from the... residues of 1,2- ethanediamine, N1-(2-aminoethyl)-, polymer with 2,4-diisocyanato-1- methylbenzene on food... apply to me? You may be potentially affected by this action if you are an agricultural producer,...

  17. 43 CFR 2201.1-2 - Segregative effect.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... System lands, which proposal shall be filed in compliance with 36 CFR part 254, the authorized officer... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Segregative effect. 2201.1-2 Section 2201... Exchanges-Specific Requirements § 2201.1-2 Segregative effect. (a) If a proposal is made to exchange...

  18. 43 CFR 2720.1-2 - Form of application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Form of application. 2720.1-2 Section 2720.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) CONVEYANCE OF FEDERALLY-OWNED MINERAL INTERESTS Conveyance of Federally-Owned...

  19. 36 CFR 1.2 - Applicability and scope.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Applicability and scope. 1.2 Section 1.2 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL... administered by the National Park Service; (2) The boundaries of lands and waters administered by the...

  20. Resolution of terminal 1,2-diols via silyl transfer.

    PubMed

    Sun, Xixi; Worthy, Amanda D; Tan, Kian L

    2013-10-18

    Through kinetic analysis and optimization, we report an improved resolution of terminal 1,2-diols via asymmetric silyl transfer. Because the reaction is a regiodivergent resolution, the monoprotected product could be isolated in excess of 95:5 er and 40% yield. The described method offers a means of chemically differentiating a terminal 1,2-diol with concomitant resolution of the enantiomers.

  1. 48 CFR 970.2201-1-2 - Policies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... absence of any illegal drug, as defined in 10 CFR Part 707.4. All positions requiring access... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Policies. 970.2201-1-2 Section 970.2201-1-2 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY...

  2. 5 CFR 1.2 - Extent of the competitive service.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Extent of the competitive service. 1.2 Section 1.2 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE RULES COVERAGE AND... pursuant to statute or by the Office of Personnel Management (hereafter referred to in this subchapter...

  3. 43 CFR 3582.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Hardrock minerals. 3582.1-2 Section 3582.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS National Park Service Areas § 3582.1-2 Hardrock minerals. Except as otherwise specifically provided in this subpart, leasing...

  4. 43 CFR 3583.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Hardrock minerals. 3583.1-2 Section 3583.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS Shasta and Trinity Units of the Whiskeytown-Shasta-Trinity National Recreation Area § 3583.1-2 Hardrock minerals. This subpart governs...

  5. 43 CFR 3583.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Hardrock minerals. 3583.1-2 Section 3583.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS Shasta and Trinity Units of the Whiskeytown-Shasta-Trinity National Recreation Area § 3583.1-2 Hardrock minerals. This subpart governs...

  6. 43 CFR 3583.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Hardrock minerals. 3583.1-2 Section 3583.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS Shasta and Trinity Units of the Whiskeytown-Shasta-Trinity National Recreation Area § 3583.1-2 Hardrock minerals. This subpart governs...

  7. 43 CFR 3582.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Hardrock minerals. 3582.1-2 Section 3582.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS National Park Service Areas § 3582.1-2 Hardrock minerals. Except as otherwise specifically provided in this subpart, leasing...

  8. 43 CFR 3583.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Hardrock minerals. 3583.1-2 Section 3583.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS Shasta and Trinity Units of the Whiskeytown-Shasta-Trinity National Recreation Area § 3583.1-2 Hardrock minerals. This subpart governs...

  9. 43 CFR 3582.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Hardrock minerals. 3582.1-2 Section 3582.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS National Park Service Areas § 3582.1-2 Hardrock minerals. Except as otherwise specifically provided in this subpart, leasing...

  10. 43 CFR 3582.1-2 - Hardrock minerals.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Hardrock minerals. 3582.1-2 Section 3582.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SPECIAL LEASING AREAS National Park Service Areas § 3582.1-2 Hardrock minerals. Except as otherwise specifically provided in this subpart, leasing...

  11. 43 CFR 3103.1-2 - Where submitted.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Where submitted. 3103.1-2 Section 3103.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT...-2 Where submitted. (a)(1) All fees for lease applications or offers or for requests for approval...

  12. 43 CFR 3103.1-2 - Where submitted.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Where submitted. 3103.1-2 Section 3103.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT...-2 Where submitted. (a)(1) All fees for lease applications or offers or for requests for approval...

  13. 43 CFR 3103.1-2 - Where submitted.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Where submitted. 3103.1-2 Section 3103.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT...-2 Where submitted. (a)(1) All fees for lease applications or offers or for requests for approval...

  14. 43 CFR 3103.1-2 - Where submitted.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Where submitted. 3103.1-2 Section 3103.1-2 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT...-2 Where submitted. (a)(1) All fees for lease applications or offers or for requests for approval...

  15. Running on age in a 15-km road run: minor influence of age on performance.

    PubMed

    Celie, Floortje; Faes, Miriam; Hopman, Maria; Stalenhoef, Anton F H; Rikkert, Marcel G M Olde

    2010-04-01

    The importance of exercise in the elderly is widely recognized, but data on performances and drop-out in short running contests are lacking. This hinders stimulation and coaching of elderly persons in active aging. The aim of the study was to determine age-related changes in running performance in the most popular Dutch road run, and how this is influenced by gender, training, and increased participation rate over the last decade. This is a retrospective analysis of 194,560 participants of a 15-km run from 1995 to 2007. Multiple regression analysis of running time by age, gender, and training was performed. Trends in participation were examined by chi-square tests and ANOVA. Trends in running time and speed were examined by t tests. With aging, running time increased with 0.20% per year (P < 0.001). Running time was on average 13% (P < 0.001) shorter in men than in women and was 15.7% (P < 0.001) shorter in participants who trained on a regular basis. Decline in performance with age was 5.9% larger for men than women (P < 0.01) and 4.5% larger for trained than untrained participants (P < 0.01). Over the last decade, participation numbers increased most for elderly (≥60 years) and female participants, mean running performance declined with 9.9% (P < 0.001). Drop-out number was low at all ages (0.13-0.29%). It appears that aging has only minor negative influences on running performance, which can even be attenuated by training. Our data suggest that exercise by means of running is a safe and rewarding option for improvement of healthy and active aging. PMID:21124752

  16. Seafloor Geodetic Evidence of Episodic Spreading 25 km East of the Juan de Fuca Ridge

    NASA Astrophysics Data System (ADS)

    Chadwell, C. D.; Spiess, F. N.; Hildebrand, J. A.; Dragert, H.

    2002-12-01

    The Juan de Fuca plate is a small oceanic plate, with no exposed landmass, encompassed by the larger Pacific and North America plates. Over geologic time, the Pacific and Juan de Fuca (JdF) plates continuously diverge along the Juan de Fuca Ridge (JdFR). GPS combined with acoustic ranging (GPS-A) provides a method to observe present-day seafloor positions with centimeter resolution. From 1994-1999, using an acoustic ranging system that straddled the JdFR Cleft Segment, we observed no spreading across a 700-m wide zone spanning the central cleft. However, seaward of the northern Cascadia Subduction Zone (CSZ), a GPS-A array was observed to move continuously between 1994 to 1996 at about the average geologic rate. These contrasting results suggest that a transition zone must exist between episodic spreading occurring at the JdFR and the continuous motion nearer the CSZ. In this zone the motion would be expected to lag behind that of the bulk of the JdF plate while the ridge crest is locked and then, subsequent to a spreading event at the ridge crest, the velocity in the transition zone would be greater than the plate average to compensate for the loss. To investigate the transition zone, we established a GPS-Acoustic reference site 25 km off-axis from the Cleft array on the east flank of the JdFR. Preliminary results from analyses of the GPS-A data collected in 2000 and 2002, while still characterized by large errors, show that this site may be lagging behind the bulk of the JdF plate. Analysis of additional data, and a scheduled 2003 return to the area, should refine these results. At this time they clearly suggest that the flank region is currently in the portion of the cycle preceding a spreading event. The work was supported by NSF-OCE-9907247.

  17. Copper-catalyzed 1,2-addition of α-carbonyl iodides to alkynes.

    PubMed

    Xu, Tao; Hu, Xile

    2015-01-19

    β,γ-Unsaturated ketones are an important class of organic molecules. Herein, copper catalysis has been developed for the synthesis of β-γ-unsaturated ketones through 1,2-addition of α-carbonyl iodides to alkynes. The reactions exhibit wide substrate scope and high functional group tolerance. The reaction products are versatile synthetic intermediates to complex small molecules. The method was applied for the formal synthesis of (±)-trichostatin A, a histone deacetylase inhibitor. PMID:25470461

  18. Copper-catalyzed 1,2-addition of α-carbonyl iodides to alkynes.

    PubMed

    Xu, Tao; Hu, Xile

    2015-01-19

    β,γ-Unsaturated ketones are an important class of organic molecules. Herein, copper catalysis has been developed for the synthesis of β-γ-unsaturated ketones through 1,2-addition of α-carbonyl iodides to alkynes. The reactions exhibit wide substrate scope and high functional group tolerance. The reaction products are versatile synthetic intermediates to complex small molecules. The method was applied for the formal synthesis of (±)-trichostatin A, a histone deacetylase inhibitor.

  19. Iron-catalyzed 1,2-addition of perfluoroalkyl iodides to alkynes and alkenes.

    PubMed

    Xu, Tao; Cheung, Chi Wai; Hu, Xile

    2014-05-01

    Iron catalysis has been developed for the intermolecular 1,2-addition of perfluoroalkyl iodides to alkynes and alkenes. The catalysis has a wide substrate scope and high functional-group tolerance. A variety of perfluoroalkyl iodides including CF3 I can be employed. The resulting perfluoroalkylated alkyl and alkenyl iodides can be further functionalized by cross-coupling reactions. This methodology provides a straightforward and streamlined access to perfluoroalkylated organic molecules.

  20. Design and mass production of the optical modules for KM3NeT-Italia project

    NASA Astrophysics Data System (ADS)

    Leonora, Emanuele; Aiello, Sebastiano; Giordano, Valentina

    2016-04-01

    The KM3NeT European project aims at constructing a km3 underwater neutrino telescope in the depths of the Mediterranean Sea. The first phase that is under construction will comprise eight tower-like detection structures (KM3NeT-Italia), which will form the internal core of a km3-scale detector. The detection element of KM3NeT-Italia, the optical module, is made of a 13-inch pressure-resistant glass-vessel that contains a single 10-inch photomultiplier and the relative electronics. The design of the whole optical module, the main results obtained from the massive photomultipliers measurements, and the foremost phases of the mass production procedure performed at the production site of Catania are also presented.

  1. Cape Canaveral, Florida range reference atmosphere 0-70 km altitude

    NASA Technical Reports Server (NTRS)

    Tingle, A. (Editor)

    1983-01-01

    The RRA contains tabulations for monthly and annual means, standard deviations, skewness coefficients for wind speed, pressure temperature, density, water vapor pressure, virtual temperature, dew-point temperature, and the means and standard deviations for the zonal and meridional wind components and the linear (product moment) correlation coefficient between the wind components. These statistical parameters are tabulated at the station elevation and at 1 km intervals from sea level to 30 km and at 2 km intervals from 30 to 90 km altitude. The wind statistics are given at approximately 10 m above the station elevations and at altitudes with respect to mean sea level thereafter. For those range sites without rocketsonde measurements, the RRAs terminate at 30 km altitude or they are extended, if required, when rocketsonde data from a nearby launch site are available. There are four sets of tables for each of the 12 monthly reference periods and the annual reference period.

  2. SIRT1, 2, 3 protect mouse oocytes from postovulatory aging.

    PubMed

    Zhang, Teng; Zhou, Yang; Li, Li; Wang, Hong-Hui; Ma, Xue-Shan; Qian, Wei-Ping; Shen, Wei; Schatten, Heide; Sun, Qing-Yuan

    2016-04-01

    The quality of metaphase II oocytes will undergo a time-dependent deterioration following ovulation as the result of the oocyte aging process. In this study, we determined that the expression of sirtuin family members (SIRT1, 2, 3) was dramatically reduced in mouse oocytes aged in vivo or in vitro. Increased intracellular ROS was observed when SIRT1, 2, 3 activity was inhibited. Increased frequency of spindle defects and disturbed distribution of mitochondria were also observed in MII oocytes aged in vitro after treatment with Nicotinamide (NAM), indicating that inhibition of SIRT1, 2, 3 may accelerate postovulatory oocyte aging. Interestingly, when MII oocytes were exposed to caffeine, the decline of SIRT1, 2, 3 mRNA levels was delayed and the aging-associated defective phenotypes could be improved. The results suggest that the SIRT1, 2, 3 pathway may play a potential protective role against postovulatory oocyte aging by controlling ROS generation. PMID:26974211

  3. SIRT1, 2, 3 protect mouse oocytes from postovulatory aging

    PubMed Central

    Zhang, Teng; Zhou, Yang; Li, Li; Wang, Hong-Hui; Ma, Xue-Shan; Qian, Wei-Ping; Shen, Wei; Schatten, Heide; Sun, Qing-Yuan

    2016-01-01

    The quality of metaphase II oocytes will undergo a time-dependent deterioration following ovulation as the result of the oocyte aging process. In this study, we determined that the expression of sirtuin family members (SIRT1, 2, 3) was dramatically reduced in mouse oocytes aged in vivo or in vitro. Increased intracellular ROS was observed when SIRT1, 2, 3 activity was inhibited. Increased frequency of spindle defects and disturbed distribution of mitochondria were also observed in MII oocytes aged in vitro after treatment with Nicotinamide (NAM), indicating that inhibition of SIRT1, 2, 3 may accelerate postovulatory oocyte aging. Interestingly, when MII oocytes were exposed to caffeine, the decline of SIRT1, 2, 3 mRNA levels was delayed and the aging-associated defective phenotypes could be improved. The results suggest that the SIRT1, 2, 3 pathway may play a potential protective role against postovulatory oocyte aging by controlling ROS generation. PMID:26974211

  4. Global Investigation of the Mg Atom and ion Layers using SCIAMACHY/Envisat Observations between 70 km and 150 km Altitude and WACCM-MG Model Results

    NASA Technical Reports Server (NTRS)

    Langowski, M.; vonSavigny, C.; Burrows, J. P.; Feng, W.; Plane, J. M. C.; Marsh, D. R.; Janches, Diego; Sinnhuber, M.; Aikin, A. C.

    2014-01-01

    Mg and Mg+ concentration fields in the upper mesosphere/lower thermosphere (UMLT) region are retrieved from SCIAMACHY/Envisat limb measurements of Mg and Mg+ dayglow emissions using a 2-D tomographic retrieval approach. The time series of monthly means of Mg and Mg+ for number density as well as vertical column density in different latitudinal regions are shown. Data from the limb mesosphere-thermosphere mode of SCIAMACHY/Envisat are used, which covers the 50 km to 150 km altitude region with a vertical sampling of 3.3 km and a highest latitude of 82 deg. The high latitudes are not covered in the winter months, because there is no dayglow emission during polar night. The measurements were performed every 14 days from mid-2008 until April 2012. Mg profiles show a peak at around 90 km altitude with a density between 750 cm(exp-3) and 2000 cm(exp-3). Mg does not show strong seasonal variation at mid-latitudes. The Mg+ peak occurs 5-15 km above the neutral Mg peak at 95-105 km. Furthermore, the ions show a significant seasonal cycle with a summer maximum in both hemispheres at mid- and high-latitudes. The strongest seasonal variations of the ions are observed at mid-latitudes between 20-40 deg and densities at the peak altitude range from 500 cm(exp-3) to 6000 cm(exp-3). The peak altitude of the ions shows a latitudinal dependence with a maximum at mid-latitudes that is up to 10 km higher than the peak altitude at the equator. The SCIAMACHY measurements are compared to other measurements and WACCM model results. In contrast to the SCIAMACHY results, the WACCM results show a strong seasonal variability for Mg with a winter maximum, which is not observable by SCIAMACHY, and globally higher peak densities. Although the peak densities do not agree the vertical column densities agree, since SCIAMACHY results show a wider vertical profile. The agreement of SCIAMACHY and WACCM results is much better for Mg+, showing the same seasonality and similar peak densities. However

  5. Review of Whole person healthcare, Volumes 1, 2, & 3 (2007).

    PubMed

    Harvey, Richard

    2009-06-01

    Reviews the book, Whole person healthcare, Volumes 1, 2, & 3 by I. A. Serlin, M. A. DiCowden, K. Rockefeller, S. Brown, J. Sonke-Henderson, R. Brandman, and J. Graham-Pole (2007). With the more-than-1,000-page tour de force titled Whole Person Healthcare, Ilene Serlin, current president of the San Francisco Psychological Association, has purposefully edited a three-volume series aimed at humanizing the fields of psychotherapy and health care. Throughout the series, all of the authors carry the message that integrative treatment strategies in psychotherapy and health care are more valuable than reductionist "treat the symptom rather than the person" approaches as a way to humanize patient-client interaction. Whole Person Healthcare persuasively presents the principle reasons for integrating human-centered strategies into psychotherapeutic and health care practices. Volume 1 of the series, Humanizing Healthcare, sets the tone for the other two volumes, providing a conceptual scaffold for framing humanistic and positive psychological theories within an applied health care setting. Volume 2 of the series, Psychology, Spirituality, and Health, focuses on presenting concrete, evidence-based examples of integrative therapeutic techniques such as imagery and visualization, meditation, meaning finding, prayer and psychospiritual practices, yoga, tai chi, and qi gong. Volume 3 of the series, The Arts and Health, provides a critically important contribution to the field because the art therapies are so often forgotten in the world of managed health care. Volume 3 gives evidence-based examples of the valuable contributions of artistic interactions within therapeutic contexts. The collection of readings in Whole Person Healthcare covers a wide spectrum of modern healing approaches, and this series is a must for any practitioner of integrative, holistic therapies. However, there are two practical barriers of note. First is cost: The price is too steep for most readers

  6. Spectroscopic Confirmation of Two Massive Red-Sequence-Selected Galaxy Clusters at z ~ 1.2 in the SpARCS-North Cluster Survey

    NASA Astrophysics Data System (ADS)

    Muzzin, Adam; Wilson, Gillian; Yee, H. K. C.; Hoekstra, Henk; Gilbank, David; Surace, Jason; Lacy, Mark; Blindert, Kris; Majumdar, Subhabrata; Demarco, Ricardo; Gardner, Jonathan P.; Gladders, Mike; Lonsdale, Carol

    2009-06-01

    The Spitzer Adaptation of the Red-sequence Cluster Survey (SpARCS) is a deep z'-band imaging survey covering the Spitzer Wide-Area Infrared Extragalactic Survey (SWIRE) Legacy fields designed to create the first large homogeneously selected sample of massive clusters at z > 1 using an infrared adaptation of the cluster red-sequence method. We present an overview of the northern component of the survey which has been observed with Canada-France-Hawaii Telescope (CFHT)/MegaCam and covers 28.3 deg2. The southern component of the survey was observed with Cerro Tololo Inter-American Observatory (CTIO)/MOSAICII, covers 13.6 deg2, and is summarized in a companion paper by Wilson et al. We also present spectroscopic confirmation of two rich cluster candidates at z ~ 1.2. Based on Nod-and-Shuffle spectroscopy from GMOS-N on Gemini, there are 17 and 28 confirmed cluster members in SpARCS J163435+402151 and SpARCS J163852+403843 which have spectroscopic redshifts of 1.1798 and 1.1963, respectively. The clusters have velocity dispersions of 490 ± 140 km s-1 and 650 ± 160 km s-1, respectively, which imply masses (M 200) of (1.0 ± 0.9) × 1014 M sun and (2.4 ± 1.8) × 1014 M sun. Confirmation of these candidates as bonafide massive clusters demonstrates that two-filter imaging is an effective, yet observationally efficient, method for selecting clusters at z > 1.

  7. Wide Angle View of Arsia Mons Volcano

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Arsia Mons (above) is one of the largest volcanoes known. This shield volcano is part of an aligned trio known as the Tharsis Montes--the others are Pavonis Mons and Ascraeus Mons. Arsia Mons is rivaled only by Olympus Mons in terms of its volume. The summit of Arsia Mons is more than 9 kilometers (5.6 miles) higher than the surrounding plains. The crater--or caldera--at the volcano summit is approximately 110 km (68 mi) across. This view of Arsia Mons was taken by the red and blue wide angle cameras of the Mars Global Surveyor Mars Orbiter Camera (MOC) system. Bright water ice clouds (the whitish/bluish wisps) hang above the volcano--a common sight every martian afternoon in this region. Arsia Mons is located at 120o west longitude and 9o south latitude. Illumination is from the left.

  8. Marshall Space Flight Center Propulsion Systems Department (PSD) Knowledge Management (KM) Initiative

    NASA Technical Reports Server (NTRS)

    Caraccioli, Paul; Varnedoe, Tom; Smith, Randy; McCarter, Mike; Wilson, Barry; Porter, Richard

    2006-01-01

    NASA Marshall Space Flight Center's Propulsion Systems Department (PSD) is four months into a fifteen month Knowledge Management (KM) initiative to support enhanced engineering decision making and analyses, faster resolution of anomalies (near-term) and effective, efficient knowledge infused engineering processes, reduced knowledge attrition, and reduced anomaly occurrences (long-term). The near-term objective of this initiative is developing a KM Pilot project, within the context of a 3-5 year KM strategy, to introduce and evaluate the use of KM within PSD. An internal NASA/MSFC PSD KM team was established early in project formulation to maintain a practitioner, user-centric focus throughout the conceptual development, planning and deployment of KM technologies and capabilities within the PSD. The PSD internal team is supported by the University of Alabama's Aging Infrastructure Systems Center of Excellence (AISCE), lntergraph Corporation, and The Knowledge Institute. The principle product of the initial four month effort has been strategic planning of PSD KNI implementation by first determining the "as is" state of KM capabilities and developing, planning and documenting the roadmap to achieve the desired "to be" state. Activities undertaken to suppoth e planning phase have included data gathering; cultural surveys, group work-sessions, interviews, documentation review, and independent research. Assessments and analyses have beon pedormed including industry benchmarking, related local and Agency initiatives, specific tools and techniques used and strategies for leveraging existing resources, people and technology to achieve common KM goals. Key findings captured in the PSD KM Strategic Plan include the system vision, purpose, stakeholders, prioritized strategic objectives mapped to the top ten practitioner needs and analysis of current resource usage. Opportunities identified from research, analyses, cultural1KM surveys and practitioner interviews include

  9. Fluorination of 1,2,3,4- and 1,2,3,5-tetrahalobenzenes with potassium fluoride in dimethyl sulfone

    USGS Publications Warehouse

    Finger, G.C.; Dickerson, D.R.; Shiley, R.H.

    1972-01-01

    1,2,3,4-Tetrachlorobenzene, 1,2,3,5-tetrachlorobenzene, 2,4,6-trichlorofluorobenzene, and 2,6-dichloro-1,4-difluorobenzene were fluorinated with potassium fluoride and potassium fluoride-cesium fluoride mixtures in dimethyl sulfone. By varying the concentration, temperature and reaction time, the degree of fluorination could be controlled to some extent. The optimum conditions for producing mono-, di- and tri-fluoro-substituted chlorobenzenes and trace amounts of tetrafluorobenzene from the corresponding tetrachlorobenzenes are given. 1,2,3,5-Tetrafluorobenzene was obtained in 44.8% yield from 2,6-dichloro-1,4-difluorobenzene. 1,2,3,4-Tetrafluorobenzene was obtained in only trace amounts from 1,2,3,4-tetrachlorobenzene. A total of 24 new chlorofluorobenzenes and intermediates are described. Fluorination with potassium fluoride and certain other metal fluorides was also investigated. ?? 1972.

  10. Compilation of known and suspected Quaternary faults within 100 km of Yucca Mountain, Nevada and California

    SciTech Connect

    Piety, L.A.

    1996-12-31

    Geologic data have been compiled for known and suspected Quaternary faults in southern Nevada and southeastern California within about 100 km of the potential repository site at Yucca Mountain. The data set includes regional studies that attempt to identify and evaluate lineaments, scraps, and other possible tectonic landforms of possible Quaternary age, detailed studies that focus on a single fault, and geologic studies that were completed for purposes other than evaluation of Quaternary fault activity. Studies included in this compilation are those that were available as of December 1993. Faults that have known or suspected Quaternary activity are presented on a topographic base map at a scale of 1:250,000. Data for each fault that are pertinent to the assessment of future faulting and earthquake events are assembled on description sheets and summarized on tables. This compilation identifies ten faults within 50 km of the site but outside the site area and an additional fourteen faults between 50 km and 100 km of the site for which evidence for Holocene or late Pleistocene surface rupture has been reported in the literature. The longest and most continuous of these faults is the northwest-striking, 250-km-long Furnace Creek fault (including its possible extension into Fish Lake Valley), which is located about 50 km west of the site. In addition to identifying known or suspected Quaternary faults within about 100 km of the site, this compilation demonstrates the lack of information for most of these faults.

  11. The LDA-1/2 technique: Recent developments

    NASA Astrophysics Data System (ADS)

    Ferreira, Luiz G.; Pelá, Ronaldo R.; Teles, Lara K.; Marques, Marcelo; Ribeiro, Mauro, Jr.; Furthmüller, Jürgen

    2013-12-01

    This paper is a review of the LDA(GGA)-1/2 method for band calculation. We review the many applications of the method: band gaps, semiconductor interfaces, semiconductor alloys. The number of applications where the method fails is minimal. Leading to results with a precision comparable to Hedin's GW method, LDA-1/2 has the advantage of being orders of magnitude faster. The paper begins by a short theoretical review in which we try not repeat what is already published. Then we present some results that are scattered in the literature. We find that LDA(GGA)-1/2 is the recommended method for excited state energy calculations.

  12. Comparative genomic analysis of the swine pathogen Bordetella bronchisepticastrain KM22.

    PubMed

    Nicholson, Tracy L; Shore, Sarah M; Register, Karen B; Bayles, Darrell O; Kingsley, Robert A; Brunelle, Brain W

    2016-01-15

    The well-characterized Bordetella bronchiseptica strain KM22, originally isolated from a pig with atrophic rhinitis, has been used to develop a reproducible swine respiratory disease model. The goal of this study was to identify genetic features unique to KM22 by comparing the genome sequence of KM22 to the laboratory reference strain RB50. To gain a broader perspective of the genetic relationship of KM22 among other B. bronchiseptica strains, selected genes of KM22 were then compared to five other B. bronchiseptica strains isolated from different hosts. Overall, the KM22 genome sequence is more similar to the genome sequences of the strains isolated from animals than the strains isolated from humans. The majority of virulence gene expression in Bordetella is positively regulated by the two-component sensory transduction system BvgAS. bopN, bvgA, fimB, and fimC were the most highly conserved BvgAS-regulated genes present in all seven strains analyzed. In contrast, the BvgAS-regulated genes present in all seven strains with the highest sequence divergence werefimN, fim2, fhaL, andfhaS. A total of eight major fimbrial subunit genes were identified in KM22. Quantitative real-time PCR data demonstrated that seven of the eight fimbrial subunit genes identified in KM22 are expressed and regulated by BvgAS. The annotation of the KM22 genome sequence, coupled with the comparative genomic analyses reported in this study, can be used to facilitate the development of vaccines with improved efficacy towards B. bronchiseptica in swine to decrease the prevalence and disease burden caused by this pathogen. PMID:26711033

  13. Comparative genomic analysis of the swine pathogen Bordetella bronchisepticastrain KM22.

    PubMed

    Nicholson, Tracy L; Shore, Sarah M; Register, Karen B; Bayles, Darrell O; Kingsley, Robert A; Brunelle, Brain W

    2016-01-01

    The well-characterized Bordetella bronchiseptica strain KM22, originally isolated from a pig with atrophic rhinitis, has been used to develop a reproducible swine respiratory disease model. The goal of this study was to identify genetic features unique to KM22 by comparing the genome sequence of KM22 to the laboratory reference strain RB50. To gain a broader perspective of the genetic relationship of KM22 among other B. bronchiseptica strains, selected genes of KM22 were then compared to five other B. bronchiseptica strains isolated from different hosts. Overall, the KM22 genome sequence is more similar to the genome sequences of the strains isolated from animals than the strains isolated from humans. The majority of virulence gene expression in Bordetella is positively regulated by the two-component sensory transduction system BvgAS. bopN, bvgA, fimB, and fimC were the most highly conserved BvgAS-regulated genes present in all seven strains analyzed. In contrast, the BvgAS-regulated genes present in all seven strains with the highest sequence divergence werefimN, fim2, fhaL, andfhaS. A total of eight major fimbrial subunit genes were identified in KM22. Quantitative real-time PCR data demonstrated that seven of the eight fimbrial subunit genes identified in KM22 are expressed and regulated by BvgAS. The annotation of the KM22 genome sequence, coupled with the comparative genomic analyses reported in this study, can be used to facilitate the development of vaccines with improved efficacy towards B. bronchiseptica in swine to decrease the prevalence and disease burden caused by this pathogen.

  14. Dosimetry of secondary cosmic radiation up to an altitude of 30 km.

    PubMed

    Wissmann, F; Burda, O; Khurana, S; Klages, T; Langner, F

    2014-10-01

    Dosimetric measurements in the field of secondary cosmic radiation were extensively made during the last years. Since the majority of these measurements were performed on-board passenger aircraft at altitudes between 10 and 12 km, measurements at higher altitudes are desirable for the verification of the legal dose assessment procedures for aircrew. A simple solution is to use a high-altitude balloon that reaches altitudes as high as 30 km. In this work, it is shown that the dose rate profile up to 30 km can be measured with acceptable uncertainties using a Si-detector. PMID:24345463

  15. Dosimetry of secondary cosmic radiation up to an altitude of 30 km.

    PubMed

    Wissmann, F; Burda, O; Khurana, S; Klages, T; Langner, F

    2014-10-01

    Dosimetric measurements in the field of secondary cosmic radiation were extensively made during the last years. Since the majority of these measurements were performed on-board passenger aircraft at altitudes between 10 and 12 km, measurements at higher altitudes are desirable for the verification of the legal dose assessment procedures for aircrew. A simple solution is to use a high-altitude balloon that reaches altitudes as high as 30 km. In this work, it is shown that the dose rate profile up to 30 km can be measured with acceptable uncertainties using a Si-detector.

  16. Characterization of the KM3NeT photomultipliers in the Hellenic Open University

    SciTech Connect

    Bourlis, G.; Avgitas, T.; Tsirigotis, A.; Tzamarias, S.; Collaboration: KM3NeT Collaboration

    2014-11-18

    The KM3NeT neutrino research infrastructure will be a deep sea multidisciplinary observatory in the Mediterranean Sea hosting a neutrino telescope. The Physics Laboratory of the Hellenic Open University is involved in the characterization of the KM3NeT neutrino detector. The present work describes measurement techniques for the functional characteristics of the candidate KM3NeT photomultipliers. These characteristics include dark current, transit time spread, gain slope and single photoelectron characteristics, as well as delayed and after pulses.

  17. An increased fluid intake leads to feet swelling in 100-km ultra-marathoners - an observational field study

    PubMed Central

    2012-01-01

    Background An association between fluid intake and changes in volumes of the upper and lower limb has been described in 100-km ultra-marathoners. The purpose of the present study was (i) to investigate the association between fluid intake and a potential development of peripheral oedemas leading to an increase of the feet volume in 100-km ultra-marathoners and (ii) to evaluate a possible association between the changes in plasma sodium concentration ([Na+]) and changes in feet volume. Methods In seventy-six 100-km ultra-marathoners, body mass, plasma [Na+], haematocrit and urine specific gravity were determined pre- and post-race. Fluid intake and the changes of volume of the feet were measured where the changes of volume of the feet were estimated using plethysmography. Results Body mass decreased by 1.8 kg (2.4%) (p < 0.0001); plasma [Na+] increased by 1.2% (p < 0.0001). Haematocrit decreased (p = 0.0005). The volume of the feet remained unchanged (p > 0.05). Plasma volume and urine specific gravity increased (p < 0.0001). Fluid intake was positively related to the change in the volume of the feet (r = 0.54, p < 0.0001) and negatively to post-race plasma [Na+] (r = -0.28, p = 0.0142). Running speed was negatively related to both fluid intake (r = -0.33, p = 0.0036) and the change in feet volume (r = -0.23, p = 0.0236). The change in the volume of the feet was negatively related to the change in plasma [Na+] (r = -0.26, p = 0.0227). The change in body mass was negatively related to both post-race plasma [Na+] (r = -0.28, p = 0.0129) and running speed (r = -0.34, p = 0.0028). Conclusions An increase in feet volume after a 100-km ultra-marathon was due to an increased fluid intake. PMID:22472466

  18. Bubble point pressures for chlorodifluoromethane + 1,2-dichloro-1,1,2,2-tetrafluoroethane, bromotrifluoromethane + 1,2-dichloro-1,1,2,2-tetrafluoroethane, and bromotrifluoromethane + chloropentafluoroethane

    SciTech Connect

    Mishima, Kenji, Hongo, Masaru; Takagi, Toshiharu; Arai, Yasuhiko . Dept. of Industrial Chemistry)

    1993-01-01

    The bubble point pressures for chlorodifluoromethane (R22) + 1,2-dichloro-1,1,2,2-tetrafluoroethane (R114), bromotrifluoromethane (R13B1) + 1,2-dichloro-1,1,2,2-tetrafluoroethane (R114), and bromotrifluoromethane (R13B1) + chloropentafluoroethane (R115) were measured by a static method. Measurements were made at various compositions at temperatures from 298.15 K to near their critical temperature. The uncertainty of the pressures was estimated to be no greater than [plus minus]0.3%. The bubble point pressures for pure substances were correlated by the Wagner equation, and those for the mixtures were also correlated by the Wagner equation, using a corresponding states principle.

  19. 14 CFR 1.2 - Abbreviations and symbols.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... affecting § 1.2, see the List of CFR Sections Affected, which appears in the Finding Aids section of the... above ground level. ALS means approach light system. APU means auxiliary power unit. ASR means...

  20. Hierarchical domain structure of lead-free piezoelectric (Na1/2 Bi1/2)TiO3-(K1/2 Bi1/2)TiO3 single crystals

    NASA Astrophysics Data System (ADS)

    Luo, Chengtao; Wang, Yaojin; Ge, Wenwei; Li, Jiefang; Viehland, Dwight; Delaire, Olivier; Li, Xiaobin; Luo, Haosu

    2016-05-01

    We report a unique hierarchical domain structure in single crystals of (Na1/2Bi1/2)TiO3-xat. %(K1/2Bi1/2)TiO3 for x = 5 and 8 by transmission electron microscopy (TEM). A high density of polar nano-domains with a lamellar morphology was found, which were self-assembled into a quadrant-like configuration, which then assembled into conventional ferroelectric macro-domains. Studies by high resolution TEM revealed that the polar lamellar regions contained a coexistence of in-phase and anti-phase oxygen octahedral tilt regions of a few nanometers in size. Domain frustration over multiple length scales may play an important role in the stabilization of the hierarchy, and in reducing the piezoelectric response of this Pb-free piezoelectric solid solution.

  1. 26 CFR 303.1-2 - Application of part.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADMINISTRATION TAXES UNDER THE TRADING WITH THE ENEMY ACT § 303.1-2 Application of part. (a) Property covered..., 1929, and Treasury Decision 4514, approved January 18, 1935 (26 CFR (1938 ed.) 452.1-452.10). (b)...

  2. Contextual view of district with Quarters 1, 2, and 3 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of district with Quarters 1, 2, and 3 in view, as well as Whiting Way, camera facing southwest - Naval Training Station, Senior Officers' Quarters District, Naval Station Treasure Island, Yerba Buena Island, San Francisco, San Francisco County, CA

  3. X-1-2 with Pilots Robert Champine Herb Hoover

    NASA Technical Reports Server (NTRS)

    1949-01-01

    The Bell Aircraft Corporation X-1-2 and two of the NACA pilots that flew the aircraft. The one on the left is Robert Champine with the other being Herbert Hoover. The X-1-2 was also equipped with the 10-percent wing and 8 percent tail, powered with an XLR-11 rocket engine and aircraft made its first powered flight on December 9, 1946 with Chalmers 'Slick' Goodlin at the controls. As with the X-1-1 the X-1-2 continued to investigate transonic/supersonic flight regime. NACA pilot Herbert Hoover became the first civilian to fly Mach 1, March 10, 1948. X-1-2 flew until October 23, 1951, completing 74 glide and powered flights with nine different pilots, when it was retired to be rebuilt as the X-1E.

  4. 2. INTAKE CHANNEL LOOKING NORTHWEST; GATES 1, 2, AND 3 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. INTAKE CHANNEL LOOKING NORTHWEST; GATES 1, 2, AND 3 SHOWING. - Hondius Water Line, 1.6 miles Northwest of Park headquarters building & 1 mile Northwest of Beaver Meadows entrance station, Estes Park, Larimer County, CO

  5. Cycloadditions of Noncomplementary Substituted 1,2,3-Triazines

    PubMed Central

    2015-01-01

    The scope of the [4 + 2] cycloaddition reactions of substituted 1,2,3-triazines, bearing noncomplementary substitution with electron-withdrawing groups at C4 and/or C6, is described. The studies define key electronic and steric effects of substituents impacting the reactivity, mode (C4/N1 vs C5/N2), and regioselectivity of the cycloaddition reactions of 1,2,3-triazines with amidines, enamines, and ynamines, providing access to highly functionalized heterocycles. PMID:25222918

  6. Structure and ferroelectric properties of Bi(Zn(1/2)Ti(1/2))O3-(Bi(1/2)K(1/2))TiO3 perovskite solid solutions.

    PubMed

    Huang, Chien-Chih; Vittayakorn, Naratip; Cann, David P

    2009-07-01

    Lead-free piezoelectric ceramics based on chiBi(Zn(1/2)Ti(1/2))O3-(1-chi)(Bi(1/2)K(1/2))TiO3 were obtained via solid state processing techniques. A single perovskite phase with tetragonal symmetry was obtained for Bi(Zn(1/2)Ti(1/2))O3 (BZT) substitutions up to 20 mol%. The maximum density was 97.1% at the composition of chi = 0.1. The dielectric measurement indicated that the transition temperature decreased linearly with increasing BZT content. The P-E loops revealed an increase in remanent polarization (P(r)) with the addition of BZT. The maximum planar coupling coefficient, kappa(p), for the chi = 0.1 composition was 21.6 and the piezoelectric coefficient, d33, for chi = 0, chi = 0.05, and chi = 0.1 was 108, 185, and 235 pm/V, respectively. Overall, the dielectric and piezoelectric properties showed significant improvement when BZT was added.

  7. Skin cancer risk in BRCA1/2 mutation carriers.

    PubMed

    Gumaste, P V; Penn, L A; Cymerman, R M; Kirchhoff, T; Polsky, D; McLellan, B

    2015-06-01

    Women with BRCA1/2 mutations have an elevated risk of breast and ovarian cancer. These patients and their clinicians are often concerned about their risk for other cancers, including skin cancer. Research evaluating the association between BRCA1/2 mutations and skin cancer is limited and has produced inconsistent results. Herein, we review the current literature on the risk of melanoma and nonmelanoma skin cancers in BRCA1/2 mutation carriers. No studies have shown a statistically significant risk of melanoma in BRCA1 families. BRCA2 mutations have been linked to melanoma in large breast and ovarian cancer families, though a statistically significant elevated risk was reported in only one study. Five additional studies have shown some association between BRCA2 mutations and melanoma, while four studies did not find any association. With respect to nonmelanoma skin cancers, studies have produced conflicting results. Given the current state of medical knowledge, there is insufficient evidence to warrant increased skin cancer surveillance of patients with a confirmed BRCA1/2 mutation or a family history of a BRCA1/2 mutation, in the absence of standard risk factors. Nonetheless, suspected BRCA1/2 mutation carriers should be counselled about skin cancer risks and may benefit from yearly full skin examinations.

  8. Mapping Land Cover Types in Amazon Basin Using 1km JERS-1 Mosaic

    NASA Technical Reports Server (NTRS)

    Saatchi, Sassan S.; Nelson, Bruce; Podest, Erika; Holt, John

    2000-01-01

    In this paper, the 100 meter JERS-1 Amazon mosaic image was used in a new classifier to generate a I km resolution land cover map. The inputs to the classifier were 1 km resolution mean backscatter and seven first order texture measures derived from the 100 m data by using a 10 x 10 independent sampling window. The classification approach included two interdependent stages: 1) a supervised maximum a posteriori Bayesian approach to classify the mean backscatter image into 5 general land cover categories of forest, savannah, inundated, white sand, and anthropogenic vegetation classes, and 2) a texture measure decision rule approach to further discriminate subcategory classes based on taxonomic information and biomass levels. Fourteen classes were successfully separated at 1 km scale. The results were verified by examining the accuracy of the approach by comparison with the IBGE and the AVHRR 1 km resolution land cover maps.

  9. Photoelectron-induced waves: A likely source of 150 km radar echoes and enhanced electron modes

    NASA Astrophysics Data System (ADS)

    Oppenheim, Meers M.; Dimant, Yakov S.

    2016-04-01

    VHF radars near the geomagnetic equator receive coherent reflections from plasma density irregularities between 130 and 160 km in altitude during the daytime. Though researchers first discovered these 150 km echoes over 50 years ago and use them to monitor vertical plasma drifts, the underlying mechanism that creates them remains a mystery. This paper uses large-scale kinetic simulations to show that photoelectrons can drive electron waves, which then enhance ion density irregularities that radars could observe as 150 km echoes. This model explains why 150 km echoes exist only during the day and why they appear at their lowest altitudes near noon. It predicts the spectral structure observed by Chau (2004) and suggests observations that can further evaluate this mechanism. It also shows the types and strength of electron modes that photoelectron-wave interactions generate in a magnetized plasma.

  10. Making sense of KM through users: Information gaps and intellectual property

    NASA Astrophysics Data System (ADS)

    Pascual, Roberto de Miguel; Casado, Esther Monterroso

    2014-10-01

    Despite its lack of definition, in a general sense, knowledge management (KM) is consubstantial to contemporary innovation-driven social systems (IDSSs), allowing individuals, organizations, and entire societies, to cope with their intrinsic technical uncertainties more effectively. Before the advent of IDSSs, most of the results of KM were considered naturally inappropriable as well as fractions of the public domain. In such context, patents litigation was almost anecdotic. This paper summarizes various social scientific and humanistic approaches that nourish the emergence of a new KM model in which innovation will be anchored in the claim for universality. Patentability of ICT and services is also considered on the realm of a commons-based KM.

  11. 26 km of offset on the Lake Clark fault since late Eocene time

    USGS Publications Warehouse

    Haeussler, Peter J.; Saltus, Richard W.

    2005-01-01

    Aeromagnetic data over the Lake Clark Fault reveal a north-trending band of magnetic anomalies that are right-laterally offset about 26 km across the fault. The magnetic anomalies correlate spatially with a belt of dated 34-39-Ma granitic plutons. Thus, the Lake Clark Fault has had ~26 km of right-lateral offset in the past 34-39 Ma. The Castle Mountain Fault, which lies along the strike of the Lake Clark Fault to the east-northeast, must have had a similar or, possibly, greater amount of offset. We infer the presence of an additional right-lateral strike-slip fault about 35 km northwest of the Lake Clark Fault, herein named the 'Telequana Fault,' on the basis of 11 km of right-lateral offset of a north-trending band of magnetic anomalies.

  12. KM3NeT tower data acquisition and data transport electronics

    NASA Astrophysics Data System (ADS)

    Nicolau, C. A.; Ameli, F.; Biagioni, A.; Capone, A.; Frezza, O.; Lonardo, A.; Masullo, R.; Mollo, C. M.; Orlando, A.; Simeone, F.; Vicini, P.

    2016-04-01

    In the framework of the KM3Net European project, the production stage of a large volume underwater neutrino telescope has started. The forthcoming installation includes 8 towers and 24 strings, that will be installed 100 km off-shore Capo Passero (Italy) at 3500 m depth. The KM3NeT tower, whose layout is strongly based on the NEMO Phase-2 prototype tower deployed in March 2013, has been re-engineered and partially re-designed in order to optimize production costs, power consumption, and usability. This contribution gives a description of the main electronics, including front-end, data transport and clock distribution system, of the KM3NeT tower detection unit.

  13. 7S(1/2) ? 9S(1/2) two-photon spectroscopy of trapped francium.

    PubMed

    Simsarian, J E; Shi, W; Orozco, L A; Sprouse, G D; Zhao, W Z

    1996-12-01

    We report on the spectroscopic measurement of the (210)Fr 9S(1/2) energy obtained by two-photon excitation of atoms confined and cooled in a magneto-optic trap. The resonant intermediate level 7P(3/2) is the upper state of the trapping transition. We have measured the energy difference between the 9S(1/2) state and the 7S(1/2) ground state to be 25 671.021 +/- 0.006 cm(-1). PMID:19881852

  14. Heavy metal effects on the biodegradation of fluorene by Sphingobacterium sp. KM-02 isolated from PAHs-contaminated mine soil

    NASA Astrophysics Data System (ADS)

    Nam, I.; Chon, C.; Jung, K.; Kim, J.

    2012-12-01

    Polycyclic aromatic hydrocarbon compounds (PAHs) are widely distributed in the environment and occur ubiquitously in fossil fuels as well as in products of incomplete combustion and are known to be strongly toxic, often with carcinogenic and mutagenic properties. Fluorene is one of the 16 PAHs included in the list of priority pollutants of the Environmental Protection Agency. The fluorene-degrading bacterial strain Sphingobacterium sp. KM-02 was isolated from PAHs-contaminated soil near an abandoned mine impacted area by selective enrichment techniques. Fluorene added to the Sphingobacterium sp. KM-02 culture as sole carbon and energy source was 78.4% removed within 120 h. A fluorene degradation pathway is tentatively proposed based on mass spectrometric identification of the metabolic intermediates 9-fluorenone, 4-hydroxy-9-fluorenone, and 8-hydroxy-3,4-benzocoumarin. Further the ability of Sphingobacterium sp. KM-02 to bioremediate 100 mg/kg fluorene in mine soil was examined by composting under laboratory conditions. Treatment of microcosm soil with the strain KM-02 for 20 days resulted in a 65.6% reduction in total amounts. These results demonstrate that Sphingobacterium sp. KM-02 could potentially be used in the bioremediation of fluorene from contaminated soil. Mine impacted area comprises considerable amounts of heavy metals such as cadmium, lead, mercury, arsenic, and copper. Although some of these metals are necessary for biological life, excessive quantities often result in the inhibition of essential biological reactions via numerous pathways. A number of reports collectively show that various metals, such as Al, Co, Ni, Cu, Zn, Pb, and Hg at a range of concentrations have adverse effects on the degradation of organic compounds. However, at present there is only limited information on the effect of individual heavy metals on the biological degradation of polyaromatic hydrocarbons (PAHs) including fluorene. Moreover, heavy metal effects were not

  15. Electron Excitation of Argon: 4s'[1/2]_1, 4p[1/2]_1, and 4p'[1/2]_0

    NASA Astrophysics Data System (ADS)

    Filipović, D. V.; Pejčev, V.; Marinković, B.; Vušković, L.

    1999-10-01

    A broad interest in low-energy electron collisions with argon has recently led to very sophisticated calculations.footnote D. H. Madison, C. M. Maloney, and J. B. Wang, J. Phys. B 31, 873 (1998).^,footnote S. Kaur, R. Srivastava, R. P. McEachran, and A. Stauffer, J. Phys. B 31, 4833 (1998).^,footnote V. Zeman, K. Bartschat, C, Noren, and J. W. McConkey, Phys. Rev. A 58, 1275 (1998). The agreement between theoretical results and the only existing full set of experimentally obtained absolute differential cross sectionsfootnote A. Chutjian and D. C. Cartwright, Phys. Rev. A 23, 2178 (1981). is not satisfactory. We have performed a set of experiments to resolve existing discrepancies between available data. At the conference we will present absolute differential cross sections for argon excited in 4s'[1/2]_1, 4p[1/2]_1, and 4p'[1/2]0 states by electron collision. The incident electron energies were in the range of 16 to 80 eV and overall energy resolution was 40 meV. The angular range covered in our experiments was 5^circ to 150^circ. Data were extrapolated to 0^circ and to 180^circ and numerically integrated to yield integral, momentum transfer, and viscosity cross sections.

  16. Hydraulic fracturing in situ stress measurements to 2.1 km depth at Cajon Pass, California

    USGS Publications Warehouse

    Healy, J.H.; Zoback, M.D.

    1988-01-01

    Stress measurements to 2.1 km reveal stress changes with depth that cannot be explained by an elastic response to uniform crustal strain. The data at about 1 km depth suggest that the stress is limited by the frictional strength of rock and is perturbed at greater depths by faults which intersect the borehole. The stress data indicate that there is little or no right-lateral shear stress acting on planes parallel to the San Andreas Fault. -Authors

  17. Using of Optic Fiber Links for Reference Frequency Transmission Over a Distance up to 85 km

    NASA Astrophysics Data System (ADS)

    Fedorova, D. M.; Malymon, A. N.; Balaev, R. I.; Kurchanov, A. F.; Troyan, V. I.

    A scheme of standard RF signal transmission over an electronically stabilized fiber link is described in the paper. The system was tested for fiber link length up to 85 km. In this scheme an intermediate controlled crystal oscillator of 100 MHz was used as a compensation node. Experimental results of the 100 MHz RF signal transmission over the 85 km optical fiber are presented. It is demonstrated that using a system of electronic compensation provides significant advantages in spatially separated standards comparison.

  18. Speed associated with plasma pH, oxygen content, total protein and urea in an 80 km race.

    PubMed

    Hoffman, R M; Hess, T M; Williams, C A; Kronfeld, D S; Griewe-Crandell, K M; Waldron, J E; Graham-Thiers, P M; Gay, L S; Splan, R K; Saker, K E; Harris, P A

    2002-09-01

    To test the hypothesis that endurance performance may be related quantitatively to changes in blood, we measured selected blood variables then determined their reference ranges and associations with speed during an 80 km race. The plan had 46 horses in a 2 x 2 factorial design testing a potassium-free electrolyte mix and a vitamin supplement. Blood samples were collected before the race, at 21, 37, 56 and 80 km, and 20 min after finishing, for assay of haematocrit, plasma pH, pO2, pCO2, [Na+], [K+], [Ca++], [Mg++], [Cl-], lactate, glucose, urea, cortisol, alpha-tocopherol, ascorbate, creatine kinase, aspartate amino transferase, lipid hydroperoxides, total protein, albumin and creatinine, and erythrocyte glutathione and glutathione peroxidase. Data from 34 finishers were analysed statistically. Reference ranges for resting and running horses were wide and overlapping and, therefore, limiting with respect to evaluation of individual horses. Speed correlations were most repeatable, with variables reflecting blood oxygen transport (enabling exercise), acidity and electrolytes (limiting exercise) and total protein (enabling then, perhaps, limiting). Stepwise regressions also included plasma urea concentration (limiting). The association of speed with less plasma acidity and urea suggests the potential for fat adaptation and protein restriction in endurance horses, as found previously in Arabians performing repeated sprints. Conditioning horses fed fat-fortified and protein-restricted diets may not only improve performance but also avoid grain-associated disorders.

  19. Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua

    PubMed Central

    Miyanaga, Akimasa; Abe, Koichi; Takahashi, Yuta; Sugimoto, Naohisa; Toyoizumi, Hiroyuki; Nakai, Hiroyuki; Kitaoka, Motomitsu; Taguchi, Hayao

    2016-01-01

    Despite the presence of β-1,2-glucan in nature, few β-1,2-glucan degrading enzymes have been reported to date. Recently, the Lin1839 protein from Listeria innocua was identified as a 1,2-β-oligoglucan phosphorylase. Since the adjacent lin1840 gene in the gene cluster encodes a putative glycoside hydrolase family 3 β-glucosidase, we hypothesized that Lin1840 is also involved in β-1,2-glucan dissimilation. Here we report the functional and structural analysis of Lin1840. A recombinant Lin1840 protein (Lin1840r) showed the highest hydrolytic activity toward sophorose (Glc-β-1,2-Glc) among β-1,2-glucooligosaccharides, suggesting that Lin1840 is a β-glucosidase involved in sophorose degradation. The enzyme also rapidly hydrolyzed laminaribiose (β-1,3), but not cellobiose (β-1,4) or gentiobiose (β-1,6) among β-linked gluco-disaccharides. We determined the crystal structures of Lin1840r in complexes with sophorose and laminaribiose as productive binding forms. In these structures, Arg572 forms many hydrogen bonds with sophorose and laminaribiose at subsite +1, which seems to be a key factor for substrate selectivity. The opposite side of subsite +1 from Arg572 is connected to a large empty space appearing to be subsite +2 for the binding of sophorotriose (Glc-β-1,2-Glc-β-1,2-Glc) in spite of the higher Km value for sophorotriose than that for sophorose. The conformations of sophorose and laminaribiose are almost the same on the Arg572 side but differ on the subsite +2 side that provides no interaction with a substrate. Therefore, Lin1840r is unable to distinguish between sophorose and laminaribiose as substrates. These results provide the first mechanistic insights into β-1,2-glucooligosaccharide recognition by β-glucosidase. PMID:26886583

  20. Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua.

    PubMed

    Nakajima, Masahiro; Yoshida, Ryuta; Miyanaga, Akimasa; Abe, Koichi; Takahashi, Yuta; Sugimoto, Naohisa; Toyoizumi, Hiroyuki; Nakai, Hiroyuki; Kitaoka, Motomitsu; Taguchi, Hayao

    2016-01-01

    Despite the presence of β-1,2-glucan in nature, few β-1,2-glucan degrading enzymes have been reported to date. Recently, the Lin1839 protein from Listeria innocua was identified as a 1,2-β-oligoglucan phosphorylase. Since the adjacent lin1840 gene in the gene cluster encodes a putative glycoside hydrolase family 3 β-glucosidase, we hypothesized that Lin1840 is also involved in β-1,2-glucan dissimilation. Here we report the functional and structural analysis of Lin1840. A recombinant Lin1840 protein (Lin1840r) showed the highest hydrolytic activity toward sophorose (Glc-β-1,2-Glc) among β-1,2-glucooligosaccharides, suggesting that Lin1840 is a β-glucosidase involved in sophorose degradation. The enzyme also rapidly hydrolyzed laminaribiose (β-1,3), but not cellobiose (β-1,4) or gentiobiose (β-1,6) among β-linked gluco-disaccharides. We determined the crystal structures of Lin1840r in complexes with sophorose and laminaribiose as productive binding forms. In these structures, Arg572 forms many hydrogen bonds with sophorose and laminaribiose at subsite +1, which seems to be a key factor for substrate selectivity. The opposite side of subsite +1 from Arg572 is connected to a large empty space appearing to be subsite +2 for the binding of sophorotriose (Glc-β-1,2-Glc-β-1,2-Glc) in spite of the higher Km value for sophorotriose than that for sophorose. The conformations of sophorose and laminaribiose are almost the same on the Arg572 side but differ on the subsite +2 side that provides no interaction with a substrate. Therefore, Lin1840r is unable to distinguish between sophorose and laminaribiose as substrates. These results provide the first mechanistic insights into β-1,2-glucooligosaccharide recognition by β-glucosidase.

  1. Emissions from an international airport increase particle number concentrations 4-fold at 10 km downwind.

    PubMed

    Hudda, Neelakshi; Gould, Tim; Hartin, Kris; Larson, Timothy V; Fruin, Scott A

    2014-06-17

    We measured the spatial pattern of particle number (PN) concentrations downwind from the Los Angeles International Airport (LAX) with an instrumented vehicle that enabled us to cover larger areas than allowed by traditional stationary measurements. LAX emissions adversely impacted air quality much farther than reported in previous airport studies. We measured at least a 2-fold increase in PN concentrations over unimpacted baseline PN concentrations during most hours of the day in an area of about 60 km(2) that extended to 16 km (10 miles) downwind and a 4- to 5-fold increase to 8-10 km (5-6 miles) downwind. Locations of maximum PN concentrations were aligned to eastern, downwind jet trajectories during prevailing westerly winds and to 8 km downwind concentrations exceeded 75 000 particles/cm(3), more than the average freeway PN concentration in Los Angeles. During infrequent northerly winds, the impact area remained large but shifted to south of the airport. The freeway length that would cause an impact equivalent to that measured in this study (i.e., PN concentration increases weighted by the area impacted) was estimated to be 280-790 km. The total freeway length in Los Angeles is 1500 km. These results suggest that airport emissions are a major source of PN in Los Angeles that are of the same general magnitude as the entire urban freeway network. They also indicate that the air quality impact areas of major airports may have been seriously underestimated. PMID:24871496

  2. Emissions from an international airport increase particle number concentrations 4-fold at 10 km downwind.

    PubMed

    Hudda, Neelakshi; Gould, Tim; Hartin, Kris; Larson, Timothy V; Fruin, Scott A

    2014-06-17

    We measured the spatial pattern of particle number (PN) concentrations downwind from the Los Angeles International Airport (LAX) with an instrumented vehicle that enabled us to cover larger areas than allowed by traditional stationary measurements. LAX emissions adversely impacted air quality much farther than reported in previous airport studies. We measured at least a 2-fold increase in PN concentrations over unimpacted baseline PN concentrations during most hours of the day in an area of about 60 km(2) that extended to 16 km (10 miles) downwind and a 4- to 5-fold increase to 8-10 km (5-6 miles) downwind. Locations of maximum PN concentrations were aligned to eastern, downwind jet trajectories during prevailing westerly winds and to 8 km downwind concentrations exceeded 75 000 particles/cm(3), more than the average freeway PN concentration in Los Angeles. During infrequent northerly winds, the impact area remained large but shifted to south of the airport. The freeway length that would cause an impact equivalent to that measured in this study (i.e., PN concentration increases weighted by the area impacted) was estimated to be 280-790 km. The total freeway length in Los Angeles is 1500 km. These results suggest that airport emissions are a major source of PN in Los Angeles that are of the same general magnitude as the entire urban freeway network. They also indicate that the air quality impact areas of major airports may have been seriously underestimated.

  3. Daytime zonal drifts in the ionospheric E and 150 km regions estimated using EAR observations

    NASA Astrophysics Data System (ADS)

    Peddapati, PavanChaitanya; Otsuka, Yuichi; Yamamoto, Mamoru; Yokoyama, Tatsuhiro; Patra, Amit

    2016-07-01

    The Equatorial Atmosphere Radar (EAR), located at Kototabang (0.2o S, 100.32o E, mag. lat. 10.36o S), Indonesia, is capable of detecting both E region and 150 km echoes during daytime. We have conducted multi-beam observations using the EAR during daytime covering all seasons to study seasonal variations of these echoes and their dynamics. Given the facts that drifts at the 150 km region are governed primarily by electric field, drifts at the E region are governed by both electric field and neutral wind, simultaneous observations of drifts in both E and 150 km regions would help understand their variations. In this paper we present local time and seasonal variations of zonal drifts in the E and 150 km regions estimated using multi-beam observations. Zonal drifts (positive eastward) in the E and 150 km regions are found to be in the range of -10 to -60 m/s and -40 to 80 m/s, respectively. In the E region, zonal drifts show height reversal and temporal variations having tidal signature and noticeable seasonal variations. Zonal drifts in the 150 km region also show noticeable height and seasonal variations. These results are compared with model drifts and evaluated in terms of electric field and neutral wind.

  4. Mean winds of the mesosphere (60-80 km), as measured by MF radars

    NASA Astrophysics Data System (ADS)

    Manson, A. H.; Meek, C. E.; Vincent, R. A.; Smith, M. J.

    1985-07-01

    Winds data obtained from medium frequency (MF) radars for heights of 60 to 80 km are discussed: locations are Saskatoon (52 N, 107 W), Christchurch (44 S, 173 W), Adelside (35 S, 183 E) and Townsville (20 S, 147 E). Whereas well defined summer easterly jets centered near 70 km develop in summer, no regular buildups and decays are observed in winter at midlatitudes. Part of this variability can be associated with stratospheric warmings, which develop into breakdown of the polar vortex in the Northern Hemisphere. Amplitude and phase profiles of the annual and semiannual oscillations are also presented. The radar winds from Saskatoon are compared and combined with rocket derived winds up to 60 km from Primrose Lake (54 N, 110 W) to give consistent cross sections from 20 to 110 km. The SH radar winds are compared with a model based on rocket winds which extends up to 80 km. The latter evidence considerable smoothing, as no winter variability is evident. The other consistent difference is that heights of the summer easterly maxima for the model are 5 to 10 km lower than the radar winds at all latitudes.

  5. Ribulose Diphosphate Carboxylase from Freshly Ruptured Spinach Chloroplasts Having an in Vivo Km[CO(2)].

    PubMed

    Bahr, J T; Jensen, R G

    1974-01-01

    The properties of a form of ribulose diphosphate carboxylase having a high affinity for CO(2) have been studied. Its apparent Km(HCO(3) (-)) of 0.5 to 0.8 mm (pH 7.8) and calculated Km(CO(2)) of 11 to 18 mum are comparable to the values exhibited by intact chloroplasts during photosynthesis. This form of the enzyme was released from chloroplasts in hypotonic media and was unstable, rapidly converting to a form having a high Km(HCO(3) (-)) of 20 to 25 mm similar to that for the purified enzyme. Incubation of the enzyme with MgCl(2) and HCO(3) (-) yielded a third form with an intermediate Km(HCO(3) (-)) of 2.5 to 3.0 mm.The low Km form had sufficient activity both at air levels of CO(2) and at saturating CO(2) to account for the rates of photosynthesis by intact chloroplasts. The low Km form could be stabilized in the presence of ribose 5-phosphate, adenosine triphosphate, and MgCl(2), at low temperatures for up to 2 hours.

  6. Will 1,2-dihydro-1,2-azaborine-based drugs resist metabolism by cytochrome P450 compound I?

    PubMed Central

    2016-01-01

    1,2-dihydro-1,2-azaborine is a structural and electronic analogue of benzene which is able to occupy benzene-binding pockets in T4 lysozyme and has been proposed as suitable arene-mimicking group for biological and pharmaceutical applications. Its applicability in a biological context requires it to be able to resist modification by xenobiotic-degrading enzymes like the P450 cytochromes. Quantum chemical computations described in this work show that 1,2-dihydro-1,2-azaborine is much more prone to modification by these enzymes than benzene, unless steric crowding of the ring prevents it from reaching the active site, or otherwise only allows reaction at the less reactive C4-position. This novel heterocyclic compound is therefore expected to be of limited usefulness as an aryl bioisostere. PMID:27547588

  7. Evaluation of the 29-km Eta Model. Part 1; Objective Verification at Three Selected Stations

    NASA Technical Reports Server (NTRS)

    Nutter, Paul A.; Manobianco, John; Merceret, Francis J. (Technical Monitor)

    1998-01-01

    This paper describes an objective verification of the National Centers for Environmental Prediction (NCEP) 29-km eta model from May 1996 through January 1998. The evaluation was designed to assess the model's surface and upper-air point forecast accuracy at three selected locations during separate warm (May - August) and cool (October - January) season periods. In order to enhance sample sizes available for statistical calculations, the objective verification includes two consecutive warm and cool season periods. Systematic model deficiencies comprise the larger portion of the total error in most of the surface forecast variables that were evaluated. The error characteristics for both surface and upper-air forecasts vary widely by parameter, season, and station location. At upper levels, a few characteristic biases are identified. Overall however, the upper-level errors are more nonsystematic in nature and could be explained partly by observational measurement uncertainty. With a few exceptions, the upper-air results also indicate that 24-h model error growth is not statistically significant. In February and August 1997, NCEP implemented upgrades to the eta model's physical parameterizations that were designed to change some of the model's error characteristics near the surface. The results shown in this paper indicate that these upgrades led to identifiable and statistically significant changes in forecast accuracy for selected surface parameters. While some of the changes were expected, others were not consistent with the intent of the model updates and further emphasize the need for ongoing sensitivity studies and localized statistical verification efforts. Objective verification of point forecasts is a stringent measure of model performance, but when used alone, is not enough to quantify the overall value that model guidance may add to the forecast process. Therefore, results from a subjective verification of the meso-eta model over the Florida peninsula are

  8. Method for preparation of 7-hydroxy-1,2,3,4-tetrahydroquinoline from 1,2,3,4-tetrahydroquinoline

    DOEpatents

    Field, G.; Hammond, P.R.

    1994-02-01

    Methods for the efficient preparation of 7-hydroxy-1,2,3,4-tetrahydroquinoline include a first method in which the acylation of m-aminophenol obtains a lactam which is reduced to give the desired quinoline and a second method in which tetrahydroquinoline is nitrated and hydrogenated and then hydrolyzed to obtain the desire quinoline. 7-hydroxy-1,2,3,4-tetrahydroquinoline is used in the efficient synthesis of four lasing dyes of the rhodamine class.

  9. A novel route to C-unsubstituted 1,2-oxaphosphetane and 1,2-oxaphospholane complexes.

    PubMed

    Kyri, A W; Schnakenburg, G; Streubel, R

    2016-06-30

    The synthesis of 1,2-oxaphosphetane complexes and 1,2-oxaphospholane complex bearing only substituents at phosphorus is reported using the reaction of Li/Cl phosphinidenoid complex with 2-iodoethanol or 3-bromo-propane-1-ol and the subsequent dehydrohalogenation using KHMDS. In contrast, the reaction of complex with (t)BuLi leads selectively to the formation of phosphinito complex .

  10. A novel route to C-unsubstituted 1,2-oxaphosphetane and 1,2-oxaphospholane complexes.

    PubMed

    Kyri, A W; Schnakenburg, G; Streubel, R

    2016-06-30

    The synthesis of 1,2-oxaphosphetane complexes and 1,2-oxaphospholane complex bearing only substituents at phosphorus is reported using the reaction of Li/Cl phosphinidenoid complex with 2-iodoethanol or 3-bromo-propane-1-ol and the subsequent dehydrohalogenation using KHMDS. In contrast, the reaction of complex with (t)BuLi leads selectively to the formation of phosphinito complex . PMID:27320731

  11. Dielectric relaxation in 0-3 PVDF-Ba(Fe1/2Nb1/2)O3 composites

    NASA Astrophysics Data System (ADS)

    Chandra, K. P.; Singh, Rajan; Kulkarni, A. R.; Prasad, K.

    2016-05-01

    (1-x)PVDF-xBa(Fe1/2Nb1/2)O3 ceramic-polymer composites with x = 0.025, 0.05, 0.10, 0.15 were prepared using melt-mixing technique. The crystal symmetry, space group and unit cell dimensions were determined from the XRD data of Ba(Fe1/2Nb1/2)O3 using FullProf software, whereas crystallite size and lattice strain were estimated using Williamson-Hall approach. The distribution of Ba(Fe1/2Nb1/2)O3 particles in the PVDF matrix were examined on the cryo-fractured surfaces using a scanning electron microscope. Cole-Cole and pseudo Cole-Cole analysis suggested the dielectric relaxation in this system to be of non-Debye type. Filler concentration dependent real and imaginary parts of dielectric constant as well as ac conductivity data followed definite trends of exponential growth types of variation.

  12. Comparison of a conventional HIV 1/2 line immunoassay with a rapid confirmatory HIV 1/2 assay.

    PubMed

    Tinguely, Caroline; Schild-Spycher, Therese; Bahador, Zahra; Gowland, Peter; Stolz, Martin; Niederhauser, Christoph

    2014-09-01

    The performance of the rapid confirmatory HIV 1/2 assay Geenius was compared with the conventional HIV 1/2 line immunoblot (INNO-LIA HIV I/II Score). One hundred HIV 1/2 confirmed positive samples from donors and patients and 136 negative screening samples from blood donors were evaluated with both assays. A 20 member performance panel consisting of different HIV 1 and 2 subtypes was also analysed. Ninety-nine of the confirmed HIV positive samples were positive with both assays. One sample was positive with the INNO-LIA HIV I/II Score but indeterminate with the Geenius HIV 1/2. From 136 negative blood donor samples (negative with a combo HIV assay and a highly sensitive ID-NAT), 125 were concordant negative. Six and five samples were incorrectly indeterminate with the INNO-LIA HIV I/II Score and the Geenius HIV 1/2, respectively. One sample was weak positive with the INNO-LIA HIV I/II Score but negative with the Geenius HIV 1/2. The 20 member performance showed equivalent results with both assays. The rapid assay showed a comparable sensitivity and specificity for confirmation for positive and negative HIV donor and patient samples as well for a 20 member performance panel.

  13. 1,2-Hydroxypyridonates as Contrast Agents for Magnetic ResonanceImaging: TREN-1,2-HOPO

    SciTech Connect

    Jocher, Christoph J.; Moore, Evan G.; Xu, Jide; Avedano, Stefano; Botta, Mauro; Aime, Silvio; Raymond, Kenneth N.

    2007-05-08

    1,2-Hydroxypyridinones (1,2-HOPO) form very stable lanthanide complexes that may be useful as contrast agents for Magnetic Resonance Imaging (MRI). X-ray diffraction of single crystals established that the solid state structures of the Eu(III) and the previously reported [Inorg. Chem. 2004, 43, 5452] Gd(III) complex are identical. The recently discovered sensitizing properties of 1,2-HOPO chelates for Eu(III) luminescence allow direct measurement of the number if water molecules in the metal complex. Fluorescence measurements of the Eu(III) complex corroborate that in solution two water molecules coordinate the lanthanide (q = 2) as proposed from the analysis of NMRD profiles. In addition, fluorescence measurements have verified the anion binding interactions of lanthanide TREN-1,2-HOPO complexes in solution, studied by relaxivity, revealing only very weak oxalate binding (K{sub A} = 82.7 {+-} 6.5 M{sup -1}). Solution thermodynamic studies of the metal complex and free ligand have been carried out using potentiometry, spectrophotometry and fluorescence spectroscopy. The metal ion selectivity of TREN-1,2-HOPO supports the feasibility of using 1,2-HOPO ligands for selective lanthanide binding [pGd = 19.3 (2); pZn = 15.2 (2), pCa = 8.8 (3)].

  14. Near infrared rubidium 62P3/2,1/2→62S1/2 laser

    NASA Astrophysics Data System (ADS)

    Moran, Paul J.; Richards, Ryan M.; Rice, Christopher A.; Perram, Glen P.

    2016-09-01

    An optically pumped near infrared rubidium (Rb) pulsed, mirrorless laser has been demonstrated in a heat pipe along both the 62P3/2-62S1/2 transition at 2.73 μm and the 62P1/2-62S1/2 transition at 2.79 μm. The bleached limit, slope efficiency, and maximum laser output energy of the near infrared Rb laser scale linearly with increasing Rb density, contrary to prior results. Previously, a maximum output energy of ~5 nJ had been observed before a rollover occurred in the scaling of output energy with rubidium concentration. In this experiment, the maximum laser output energy observed was ~100 nJ, with no indication of any scaling limitation. A maximum slope efficiency of 1.7×10-4 was observed. A small percentage of the pump photons were absorbed even at the maximum Rb density attainable in the heat pipe, indicating that laser efficiency could be scaled to near the quantum efficiency. Additionally, the hyperfine structure and absorption spectral profile of the 52S1/2-62P1/2 and 52S1/2-62P3/2 (blue) pump transitions were studied using a cw pump source.

  15. Thermal mapping of Ceres at 1.2 mm with ALMA

    NASA Astrophysics Data System (ADS)

    Moullet, Arielle; Li, Jian-Yang; Titus, Timothy N.; Sykes, Mark V.; Ip, Wing-Huen; Lai, Ian-Lin

    2016-10-01

    Ceres' thermal emission distribution, which can be characterized through observations at IR and longer wavelengths, is indicative of radiative and physical properties of its surface such as thermal inertia and roughness. High-resolution maps from the Dawn mission now provide an exquisite geographic and geological context for the interpretation of temperature features, which are at large not accessible to the spacecraft's instruments. In particular, the presence of hydrated minerals and distinctive geological features suggest the existence of ice water reservoirs near the surface, which may be characterized through the analysis of thermal inertia distributions.We report on observations obtained in Fall 2015 at the Atacama Large Millimeter Array (ALMA), sampling most of the rotation of Ceres and hence allowing one to disentangle local-hour effects from geographical thermal features. The observations were performed during the 2015 Long Baseline Campaign, offering baselines as long as 10 km and yielding a spatial resolution down to 30 mas (~45 km at the equator). At the observed wavelength of 1.2 mm, the thermal emission probes both the emission from the surface and from deeper layers, down to the level of the diurnal skin depth, hence accessing regions where water ice could be stable.We will describe the diurnal and latitudinal temperature variations derived from our observations as well as preliminary results from thermal modeling in terms of subsurface thermal inertia and ice table latitudinal extent. This work is supported by the NASA Solar System Observations Program grant NNX15AE02G.

  16. Development of Wide Band Feeds

    NASA Astrophysics Data System (ADS)

    Ujihara, H.; Ichikawa, R.

    2012-12-01

    Wide Band feeds are being developed at NICT, NAOJ, and some universities in Japan for VLBI2010, SKA, and MARBLE. SKA, the Square Kilometre Array, will comprise thousands of radio telescopes with square kilometer aperture size for radio astronomy. MARBLE consists of small portable VLBI stations developed at NICT and GSI in Japan. They all need wide band feeds with a greater than 1:10 frequency ratio. Thus we have been studying wide band feeds with dual linear polarization for these applications.

  17. Wide swath and high resolution optical imaging satellite of Japan

    NASA Astrophysics Data System (ADS)

    Katayama, Haruyoshi; Kato, Eri; Imai, Hiroko; Sagisaka, Masakazu

    2016-05-01

    The "Advanced optical satellite" (tentative name) is a follow-on mission from ALOS. Mission objectives of the advanced optical satellite is to build upon the existing advanced techniques for global land observation using optical sensors, as well as to promote data utilization for social needs. Wide swath and high resolution optical imager onboard the advanced optical satellite will extend the capabilities of earlier ALOS missions. The optical imager will be able to collect high-resolution (< 1 m) and wide-swath (70 km) images with high geo-location accuracy. This paper introduces a conceptual design of the advanced optical satellite.

  18. Olivine-wadsleyite-pyroxene topotaxy: Evidence for coherent nucleation and diffusion-controlled growth at the 410-km discontinuity

    NASA Astrophysics Data System (ADS)

    Smyth, Joseph R.; Miyajima, Nobuyoshi; Huss, Gary R.; Hellebrand, Eric; Rubie, David C.; Frost, Daniel J.

    2012-06-01

    We have synthesized a hydrous peridotite-composition sample at 13 GPa and 1400 °C with co-existing coarse grains (˜100 μm) of olivine, wadsleyite, clinoenstatite, plus melt in a multi-anvil press. Some of the olivine grains contain fine-scale (0.5-2 μm-wide) lamellae of wadsleyite and clinoenstatite that likely resulted from transformation caused by small temperature fluctuations during the four-hour experiment. Phase compositions were determined by electron probe microanalysis (EPMA) and secondary ion mass spectroscopy (SIMS). The olivine ranges from Fo94 to Fo90 in composition and contains about 4000 ppm wt. H2O. The wadsleyite is Fo87±1 in composition and contains about 10,000 ppm wt. H2O. The clinoenstatite is En93±1 in composition and about 1400 ppm wt. H2O. Transmission electron microscopy of the wadsleyite lamellae and host olivine shows that the two phases share their close-packed oxygen planes so that the wadsleyite lamellae are nearly planar and perpendicular to the [1 0 0] of olivine. The wadsleyite lamellae thus have their {1 0 1} and {0 2 1} planes parallel to the (1 0 0) plane of olivine. Additionally, larger incoherent grains of wadsleyite in olivine are found. Dislocation microtexures in the olivine and iron concentration profiles across the lamella interface suggest heterogeneous nucleation and diffusion-controlled growth of coherent wadsleyite lamellae on defects in the olivine followed by the nucleation of faster-growing incoherent grains on the lamellae. The results show that, under hydrous conditions, the olivine-wadsleyite transformation occurs close to equilibrium at conditions of the 410-km discontinuity. Furthermore, inheritance of crystallographic preferred orientations (and therefore seismic anisotropy) across the 410-km discontinuity is unlikely to be significant. In addition, hydrogen distributions among the various phases indicate that dehydration by melt extraction at 410 km will be inefficient and that H contents greater than

  19. 500 km unrepeatered 200 Gbit·s-1 transmission over a G.652-compliant ultra-low loss fiber only

    NASA Astrophysics Data System (ADS)

    Gainov, V. V.; Gurkin, N. V.; Lukinih, S. N.; Shikhaliev, I. I.; Skvortsov, P. I.; Makovejs, S.; Akopov, S. G.; Ten, S. Y.; Nanii, O. E.; Treshchikov, V. N.

    2015-06-01

    In this work we experimentally demonstrate 200 Gb·s-1 (2  ×  100 G) unrepeatered transmission over 502.1 km using a dual polarization quadrature phase-shift-keyed (DP-QPSK) format and real-time processing. Such ultra-long distance is enabled by the use of high-performance 100 G DP-QPSK transponders (the required optical signal-to-noise ratio is 12 dB), Corning® SMF-28® ULL fiber (the average attenuation of the spools used in this experiment ~0.160 dB km-1), and optimization of remotely pumped optical amplifiers, bidirectional Raman amplifiers, and dispersion precompensation.

  20. Wide aperture seismic recording in offshore west Sicily and Bolivia

    SciTech Connect

    Tilander, N.G.; Lattimore, R.K.

    1994-12-31

    Seismic operations using the Wide Aperture Recording (WAR) technique were carried out in offshore west Sicily (16.5 km offsets) and in the Sub-Andean Cordillera of Bolivia (9.0 km offsets) where conventional offset data have traditionally proved inadequate for imaging complex subsurface structures. In both cases, noise-free wide aperture events were visible at long offsets, and were successfully stacked using both hyperbolic and linear moveout. In the Sicily datasets, the resulting seismic images disagree with earlier structural interpretations, but the lack of reliable ``calibration`` data in terms of well control or usable conventional seismic data make final evaluation and interpretation of the Sicily wide aperture data ambiguous. In Bolivia good quality seismic data are present across a portion of the WAR survey; the results show that the wide aperture technique may produce a valid structural image, provided the subsurface geometries are sufficiently broad and shallow. For tight structures, the technique is unlikely to produce valid images. In general, the authors` studies show that considerable effort is required at the data processing and interpretation stage, including full waveform and ray-trace modeling, in order to identify event arrivals and to attempt to validate the wide aperture structural images. Reliable calibration data in the form of well control or conventional seismic data are needed in order to provide an understanding of the WAR results.

  1. The isolated 678-km deep 30 May 2015 MW 7.9 Ogasawara (Bonin) Islands earthquake

    NASA Astrophysics Data System (ADS)

    Ye, L.; Lay, T.; Zhan, Z.; Kanamori, H.; Hao, J.

    2015-12-01

    Deep-focus earthquakes, located 300 to 700 km below the Earth's surface within sinking slabs of relatively cold oceanic lithosphere, are mysterious phenomena. Seismic radiation from deep events is essentially indistinguishable from that for shallow stick-slip frictional-sliding earthquakes, but the confining pressure and temperature are so high for deep-focus events that a distinct process is likely needed to account for their abrupt energy release. The largest recorded deep-focus earthquake (MW 7.9) in the Izu-Bonin slab struck on 30 May 2015 beneath the Ogasawara (Bonin) Islands, isolated from prior seismicity by over 100 km in depth, and followed by only 2 small aftershocks. Globally, this is the deepest (678 km) major (MW > 7) earthquake in the seismological record. Seismicity indicates along-strike contortion of the Izu-Bonin slab, with horizontal flattening near a depth of 550 km in the Izu region and progressive steepening to near-vertical toward the south above the location of the 2015 event. Analyses of a large global data set of P, SH and pP seismic phases using short-period back-projection, subevent directivity, and broadband finite-fault inversion indicate that the mainshock ruptured a shallowly-dipping fault plane with patchy slip that spread over a distance of ~40 km with variable expansion rate (~5 km/s down-dip initially, ~3 km/s up-dip later). During the 17 s rupture duration the radiated energy was ~3.3 x 1016 J and the stress drop was ~38 MPa. The radiation efficiency is moderate (0.34), intermediate to that of the 1994 Bolivia and 2013 Sea of Okhotsk MW 8.3 earthquakes, indicating a continuum of processes. The isolated occurrence of the event suggests that localized stress concentration associated with the pronounced deformation of the Izu-Bonin slab likely played a role in generating this major earthquake.

  2. The Trigger and Data Acquisition System for the KM3NeT neutrino telescope

    NASA Astrophysics Data System (ADS)

    Pellegrino, Carmelo; Chiarusi, Tommaso

    2016-04-01

    KM3NeT is a large research infrastructure in the Mediterranean Sea that includes a network of deep-sea neutrino telescopes. The telescopes consist of vertical detection units carrying optical modules, whose separation is optimised according to the different ranges of neutrino energy that shall be explored. Two building blocks, each one made of 115 detection units, will be deployed at the KM3NeT-IT site, about 80 km from Capo Passero, Italy, to search for high-energy neutrino sources (ARCA); another building block will be installed at the KM3NeT-Fr site, about 40 km from Toulon, France, to study the hierarchy of neutrino masses (ORCA). The modular design of the KM3NeT allows for a progressive implementation and data taking even with an incomplete detector. The same scalable design is used for the Trigger and Data Acquisition Systems (TriDAS). In order to reduce the complexity of the hardware inside the optical modules, the "all data to shore" concept is adopted. This implies that the throughput is dominated by the optical background due to the decay of 40K dissolved in the sea water and to the bursts of bioluminescence, about 3 orders of magnitude larger than the physics signal, ranging from 20 Gbps to several hundreds Gbps, according to the number of detection units. In addition, information from the acoustic positioning system of the detection units must be transmitted. As a consequence of the detector construction, the on-shore DAQ infrastructure must be expanded to handle an increasing data-rate and implement an efficient fast data filtering for both the optical and acoustic channels. In this contribution, the Trigger and Data Acquisition System designed for the Phase 1 of KM3NeT and its future expansion are presented. The network infrastructure, the shore computing resources and the developed applications for handling, filtering and monitoring the optical and acoustic data-streams are described.

  3. Estimation and Attribution of the Temperature Variances in Height Range 60~140 km

    NASA Astrophysics Data System (ADS)

    Chen, Zeyu

    The SABER/TIMED temperatures collected during 2002 2006 are used to estimate for height range 60 120 km the variances of temperature (Temp-VARs) that are contributed from nonstationary perturbations. The estimation results disclose that the height range 60 140 km can be separated into two regions that are characterized by significant differences of the attributions of the Temp-VARs. In the region below 100 km height, the Temp-VARs generally increase with height, the corresponding standard deviations of temperature (Temp-SDEVs) ranges from 4 K at 60 km and 18 K at 100 km. The regions exhibiting intense Temp-VARs appear at the equator and the extra-tropics of both hemispheres. Moreover, these non-stationary temperature disturbances can be accounted primarily by the tidal variances that are derived independently by using the same data-set, in particular by the migrating diurnal, semidiurnal, and terdiurnal tide. It is also found that the region above 100 km is characterized by surprisingly large Temp-VARs with the corresponding Temp-SDEVs greater than 30 K. In a height-latitude cross-section, a stagnant maximum of Temp-SDEVs embraced by the 30-K contour remains over the course of a year at the Equator in a narrow height range 110 125 km. At the same height in Southern hemisphere, the same kind maxima appears at latitudes from the extra-tropics to polar region except during the June solstice. In contrast, the maxima appearing in Northern hemisphere high latitudes exhibits intra-seasonal variations, there such maximum are seen during the course of a year. Further investigation results confirm that the large Temp-VARs have no relevance to the tidal variances, implying the control from other processes, e.g., non-stationary planetary waves. The details will be introduced in the presentation.

  4. CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease

    PubMed Central

    Bhat, Shambhu; Dao, David T.; Terrillion, Chantelle E.; Arad, Michal; Smith, Robert J.; Soldatov, Nikolai M.; Gould, Todd D.

    2012-01-01

    One of the most consistent genetic findings to have emerged from bipolar disorder genome wide association studies (GWAS) is with CACNA1C, a gene that codes for the α1C subunit of the Cav1.2 voltage-dependent L-type calcium channel (LTCC). Genetic variation in CACNA1C have also been associated with depression, schizophrenia, autism spectrum disorders, as well as changes in brain function and structure in control subjects who have no diagnosable psychiatric illness. These data are consistent with a continuum of shared neurobiological vulnerability between diverse—Diagnostic and Statistical Manual (DSM) defined—neuropsychiatric diseases. While involved in numerous cellular functions, Cav1.2 is most frequently implicated in coupling of cell membrane depolarization to transient increase of the membrane permeability for calcium, leading to activation and, potentially, changes in intracellular signaling pathway activity, gene transcription, and synaptic plasticity. Cav1.2 is involved in the proper function of numerous neurological circuits including those involving the hippocampus, amygdala, and mesolimbic reward system, which are strongly implicated in psychiatric disease pathophysiology. A number of behavioral effects of LTCC inhibitors have been described including antidepressant-like behavioral actions in rodent models. Clinical studies suggest possible treatment effects in a subset of patients with mood disorders. We review the genetic structure and variation of CACNA1C, discussing relevant human genetic and clinical findings, as well as the biological actions of Cav1.2 that are most relevant to psychiatric illness. PMID:22705413

  5. Existence of independent [1, 2]-sets in caterpillars

    NASA Astrophysics Data System (ADS)

    Santoso, Eko Budi; Marcelo, Reginaldo M.

    2016-02-01

    Given a graph G, a subset S ⊆ V (G) is an independent [1, 2]-set if no two vertices in S are adjacent and for every vertex ν ∈ V (G)/S, 1 ≤ |N(ν) ∩ S| ≤ 2, that is, every vertex ν ∈ V (G)/S is adjacent to at least one but not more than two vertices in S. In this paper, we discuss the existence of independent [1, 2]-sets in a family of trees called caterpillars.

  6. UNUSUALLY WIDE BINARIES: ARE THEY WIDE OR UNUSUAL?

    SciTech Connect

    Kraus, Adam L.; Hillenbrand, Lynne A. E-mail: lah@astro.caltech.ed

    2009-10-01

    We describe an astrometric and spectroscopic campaign to confirm the youth and association of a complete sample of candidate wide companions in Taurus and Upper Sco. Our survey found 15 new binary systems (three in Taurus and 12 in Upper Sco) with separations of 3''-30'' (500-5000 AU) among all of the known members with masses of 2.5-0.012 M {sub sun}. The total sample of 49 wide systems in these two regions conforms to only some expectations from field multiplicity surveys. Higher mass stars have a higher frequency of wide binary companions, and there is a marked paucity of wide binary systems near the substellar regime. However, the separation distribution appears to be log-flat, rather than declining as in the field, and the mass ratio distribution is more biased toward similar-mass companions than the initial mass function or the field G-dwarf distribution. The maximum separation also shows no evidence of a limit at approx<5000 AU until the abrupt cessation of any wide binary formation at system masses of approx0.3 M {sub sun}. We attribute this result to the post-natal dynamical sculpting that occurs for most field systems; our binary systems will escape to the field intact, but most field stars are formed in denser clusters and undergo significant dynamical evolution. In summary, only wide binary systems with total masses approx<0.3 M {sub sun} appear to be 'unusually wide'.

  7. Acute Impact of Inhaled Short Acting B2-Agonists on 5 Km Running Performance

    PubMed Central

    Dickinson, John; Hu, Jiu; Chester, Neil; Loosemore, Mike; Whyte, Greg

    2014-01-01

    Whilst there appears to be no ergogenic effect from inhaled salbutamol no study has investigated the impact of the acute inhalation of 1600 µg, the World Anti-Doping Agency (WADA) daily upper limit, on endurance running performance. To investigate the ergogenic effect of an acute inhalation of short acting β2-agonists at doses up to 1600 µg on 5 km time trial performance and resultant urine concentration. Seven male non-asthmatic runners (mean ± SD; age 22.4 ± 4.3 years; height 1.80 ± 0.07 m; body mass 76.6 ± 8.6 kg) provided written informed consent. Participants completed six 5 km time-trials on separate days (three at 18 °C and three at 30 °C). Fifteen minutes prior to the initiation of each 5 km time-trial participants inhaled: placebo (PLA), 800 µg salbutamol (SAL800) or 1600 µg salbutamol (SAL1600). During each 5 km time-trial HR, VO2, VCO2, VE, RPE and blood lactate were measured. Urine samples (90 ml) were collected between 30-180 minutes post 5 km time-trial and analysed for salbutamol concentration. There was no significant difference in total 5 km time between treatments (PLA 1714.7 ± 186.2 s; SAL800 1683.3 ± 179.7 s; SAL1600 1683.6 ± 190.7 s). Post 5 km time-trial salbutamol urine concentration between SAL800 (122.96 ± 69.22 ug·ml-1) and SAL1600 (574.06 ± 448.17 ug·ml-1) were not significantly different. There was no improvement in 5 km time-trial performance following the inhalation of up to 1600 µg of salbutamol in non-asthmatic athletes. This would suggest that the current WADA guidelines, which allow athletes to inhale up to 1600 µg per day, is sufficient to avoid pharmaceutical induced performance enhancement. Key points Inhaling up to 1600 µg of Salbutamol does not result in improved 5 km time trial performance. The position of Salbutamol on the World Anti-Doping Agency list of prohibited appears justified. Athletes who use up to 1600 µg Salbutamol in one day need to review their therapy as it would suggest their respiratory

  8. Enzyme activity and gene expression profiles of Xanthobacter autotrophicus GJ10 during aerobic biodegradation of 1,2-dichloroethane.

    PubMed

    Kumar, Ajit; Pillay, Balakrishna; Olaniran, Ademola O

    2015-08-01

    Xanthobacter autotrophicus GJ10 has been widely studied because of its ability to degrade halogenated compounds, especially 1,2-dichloroethane (1,2-DCA), which is achieved through chromosomal as well as plasmid pAUX1 encoded 1,2-DCA degrading genes. This work described the gene expression and enzyme activity profiles as well as the intermediates formed during the 1,2-DCA degradation by this organism. A correlation between gene expression, enzyme activity and metabolic intermediates, after the induction of GJ10 grown culture with 1,2-DCA, was established at different time intervals. Haloalkane dehalogenase (dhlA) and haloacid dehalogenase (dhlB) were constitutively expressed while the expression of alcohol dehydrogenase (max) and aldehyde dehydrogenase (ald) was found to be inducible. The DhlA and DhlB activities were relatively higher compared to that of the inducible enzymes, Max and Ald. To the best of our knowledge, this is the first study to correlate gene expression profiles with enzyme activity and metabolite formation during 1,2-DCA degradation process in GJ10. Findings from this study may assist in fully understanding the mechanism of 1,2-DCA degradation by GJ10. It could also assist in the design and implementation of appropriate bioaugmentation strategies for complete removal of 1,2-DCA from contaminated environment.

  9. Operation and results of the prototype KM3NeT detection unit

    NASA Astrophysics Data System (ADS)

    Biagi, Simone

    2016-07-01

    KM3NeT will be a km3-scale neutrino telescope in the Mediterranean Sea. The detector will consist of blocks of about one hundred detection units. Each detection unit will host 18 digital optical modules, connected along a 700 m-long vertical structure. Electro-optical cables allow for data transmission and power supply to the optical modules. The optical module comprises 31 photomultiplier tubes of 3'', instruments to monitor environmental variables and electronic boards to communicate onshore and operate the photomultipliers. A prototype detection unit has been deployed in May 2014 at the KM3NeT-It installation site 80 km SE offshore of Capo Passero, Sicily. This prototype allowed to test the deployment procedures, the mechanics and the electronic of the apparatus, the data taking and analysis procedures. A general description of the detector and some results of the prototype are presented. The first detection unit of the KM3NeT neutrino telescope will be deployed and become operative by the end of 2015.

  10. M. tuberculosis ferritin (Rv3841): Potential involvement in Amikacin (AK) & Kanamycin (KM) resistance.

    PubMed

    Sharma, Divakar; Lata, Manju; Faheem, Mohammad; Khan, Asad Ullah; Joshi, Beenu; Venkatesan, Krishnamurthy; Shukla, Sangeeta; Bisht, Deepa

    2016-09-16

    Tuberculosis is an infectious disease, caused by one of the most successful human pathogen, Mycobacterium tuberculosis. Aminoglycosides, Amikacin (AK) & Kanamycin (KM) are commonly used to treat drug resistant tuberculosis. They target the protein synthesis machinery by interacting with several steps of translation. Several explanations have been proposed to explain the mechanism of aminoglycoside resistance but still our information is inadequate. Iron storing/interacting proteins were found to be overexpressed in aminoglycosides resistant isolates. Iron assimilation and utilization in M. tuberculosis plays a crucial role in growth, virulence and latency. To establish the relationship of ferritin with AK & KM resistance ferritin (Rv3841/bfrB) was cloned, expressed and antimicrobial drug susceptibility testing (DST) was carried out. Rv3841/bfrB gene was cloned and expressed in E. coli BL21 using pQE2 expression vector. Etest results for DST against AK & KM showed that the minimum inhibitory concentration (MIC) of ferritin recombinant cells was changed. Recombinants showed two fold changes in MIC with AK and three fold with KM E-strips. Overexpression of ferritin reflect the MIC shift which might be playing a critical role in the survival of mycobacteria by inhibiting/modulating the effects of AK & KM. String analysis also suggests that ferritin interacted with few proteins which are directly and indirectly involved in M. tuberculosis growth, Iron assimilation, virulence, resistance, stresses and latency. PMID:27521892

  11. Comparison of differences between MODIS 250 m and 1 km cloud masks

    NASA Astrophysics Data System (ADS)

    Kotarba, Andrzej Z.

    2016-11-01

    The spatial resolution of remote sensing instruments installed onboard satellites is one of the key factors for accurate estimations of cloud amount. In general terms, the larger the instantaneous field of view (IFOV), the greater the overestimation of cloud amount - assuming that data are collected with exactly the same methodology, and processed with exactly the same algorithms. While most meteorological imagers collect data at a spatial resolution of 1 km, the Moderate Resolution Imaging Spectroradiometer (MODIS) offers cloud amount estimates at both 1 km (the standard product) and 250 m (additional, high-resolution products). However, these datasets are produced using different methodological approaches, which impacts the quality and reliability of the product. This study compared 250 m data with 1 km data over elevated terrain with complex orography. Results showed significant discrepancies between the datasets, with 250 m data reporting mean seasonal (June-August) cloud amount 15.8% lower, than 1 km dataset. This was not related to the presence of snow, or to the increased spatial resolution of the cloud mask. On the other hand, both 1 km and 250 m data described similar spatial variability in mean monthly cloud amount (correlation coefficients of 0.85-0.98, p < 0.01).

  12. The Effect of Boron on the Low Cycle Fatigue Behavior of Disk Alloy KM4

    NASA Technical Reports Server (NTRS)

    Gabb, Timothy; Gayda, John; Sweeney, Joseph

    2000-01-01

    The durability of powder metallurgy nickel base superalloys employed as compressor and turbine disks is often limited by low cycle fatigue (LCF) crack initiation and crack growth from highly stressed surface locations (corners, holes, etc.). Crack growth induced by dwells at high stresses during aerospace engine operation can be particularly severe. Supersolvus solution heat treatments can be used to produce coarse grain sizes approaching ASTM 6 for improved resistance to dwell fatigue crack growth. However, the coarse grain sizes reduce yield strength, which can lower LCF initiation life. These high temperature heat treatments also can encourage pores to form. In the advanced General Electric disk superalloy KM4, such pores can initiate fatigue cracks that limit LCF initiation life. Hot isostatic pressing (HIP) during the supersolvus solution heat treatment has been shown to improve LCF initiation life in KM4, as the HIP pressure minimizes formation of the pores. Reduction of boron levels in KM4 has also been shown to increase LCF initiation life after a conventional supersolvus heat treatment, again possibly due to effects on the formation tendencies of these pores. However, the effects of reduced boron levels on microstructure, pore characteristics, and LCF failure modes in KM4 still need to be fully quantified. The objective of this study was to determine the effect of boron level on the microstructure, porosity, LCF behavior, and failure modes of supersolvus heat treated KM4.

  13. Fluid replacement strategy during a 27-Km trail run in hot and humid conditions.

    PubMed

    Baillot, M; Le Bris, S; Hue, O

    2014-02-01

    We evaluated the effects of the fluid replacement strategy on core temperature, heart rate and urine osmolality during a 27-km trail run in tropical climate. 20 well-trained runners completed a 27-km trail race in tropical conditions. They were acclimatized to these conditions. Heart rate was monitored every 5 s, while core temperature and perceived thermal and comfort sensations were recorded before, at the 11(th) km, and just after the end of the race. Water intake, urine osmolality and body mass were measured before and after the race. Core temperature and the scores of perceived thermal and comfort sensations were significantly higher at the 11(th) km and at the end of the race compared to before the race, but not at the 11(th) km compared to the end of the race [corrected]. No participant exhibited dehydration as assessed by urine osmolality. The less the trail runners weighed, the greater the heat retention was. The less hot they felt at the end of the race, the more they lost water, and the better the performance was. The fastest runners were able to tolerate a greater variation in core temperature between the beginning and the end of the trail race with lower water intake. PMID:23868683

  14. Polydatin induces bone marrow stromal cells migration by activation of ERK1/2.

    PubMed

    Chen, ZhenQiu; Wei, QiuShi; Hong, GuoJu; Chen, Da; Liang, Jiang; He, Wei; Chen, Mei Hui

    2016-08-01

    Bone marrow stromal cells (BMSCs) have proven to be useful for the treatment of numerous human diseases. However, the reparative ability of BMSCs is limited by their poor migration. Polydatin, widely used in traditional Chinese remedies, has proven to exert protective effects to BMSCs. However, little is known about its role in BMSCs migration. In this study, we studied the effects of polydatin on rat BMSCs migration using the scratch wound healing and transwell migration assays. Our results showed polydatin could promote BMSCs migration. Further experiments showed activation of ERK 1/2, but not JNK, was required for polydatin-induced BMSCs migration, suggesting that polydatin may promote BMSCs migration via the ERK 1/2 signaling pathways. Taken together, our results indicate that polydatin might be beneficial for stem cell replacement therapy by improving BMSCs migration.

  15. L1/2 regularization based numerical method for effective reconstruction of bioluminescence tomography

    NASA Astrophysics Data System (ADS)

    Chen, Xueli; Yang, Defu; Zhang, Qitan; Liang, Jimin

    2014-05-01

    Even though bioluminescence tomography (BLT) exhibits significant potential and wide applications in macroscopic imaging of small animals in vivo, the inverse reconstruction is still a tough problem that has plagued researchers in a related area. The ill-posedness of inverse reconstruction arises from insufficient measurements and modeling errors, so that the inverse reconstruction cannot be solved directly. In this study, an l1/2 regularization based numerical method was developed for effective reconstruction of BLT. In the method, the inverse reconstruction of BLT was constrained into an l1/2 regularization problem, and then the weighted interior-point algorithm (WIPA) was applied to solve the problem through transforming it into obtaining the solution of a series of l1 regularizers. The feasibility and effectiveness of the proposed method were demonstrated with numerical simulations on a digital mouse. Stability verification experiments further illustrated the robustness of the proposed method for different levels of Gaussian noise.

  16. Combination of skull traction with posterior C1-2 fusion for old C1-2 dislocations.

    PubMed

    Li, Xue Feng; Yang, Hui Lin; Jiang, Wei Min; Tang, Tian Si; Gong, Xiao Hong; Yuan, Jing; Zhang, Ji Gang; Wang, Gen Lin

    2011-06-01

    Between January 2003 and December 2009, 23 patients who had suffered old C1-2 dislocations, were surgically treated in our orthopedics department. Fifteen patients underwent direct posterior C1-2 fusion following pre-operative reduction by skull traction. In eight patients, reduction was achieved only by skull traction under general anesthesia, facilitated by manual hyperextension of the cervical spine and maintained by simultaneous posterior C1-2 fusion. Intra-operative traction was monitored using C-arm fluoroscopy and cortical somatosensory-evoked potentials. Posterior C1-2 fixation was achieved in nine patients using C1-2 laminar hooks and in 14 patients using C1 laminar hooks with C2 pedicle screws. During the follow-up of 5 to 72 months (mean: 42.8 months), solid bony fusion was accomplished in all patients. Using Di Lorenzo's grades and Japanese Orthopedics Association scores, there was significant improvement (p<0.05). The cervical medullary angle exhibited a significant improvement of 31.7°, from 121.6° to 153.3° (p<0.05). There were no complications, including dural tears, spinal cord damage, vertebral artery damage, or breakage or loosening of implants.

  17. Seismic imaging in the eastern Scandinavian Caledonides: siting the 2.5 km deep COSC-2 borehole, central Sweden

    NASA Astrophysics Data System (ADS)

    Juhlin, Christopher; Hedin, Peter; Gee, David G.; Lorenz, Henning; Kalscheuer, Thomas; Yan, Ping

    2016-05-01

    The Collisional Orogeny in the Scandinavian Caledonides (COSC) project, a contribution to the International Continental Scientific Drilling Program (ICDP), aims to provide a deeper understanding of mountain belt dynamics. Scientific investigations include a range of topics, from subduction-related tectonics to the present-day hydrological cycle. COSC investigations and drilling activities are focused in central Scandinavia, where rocks from the middle to lower crust of the orogen are exposed near the Swedish-Norwegian border. Here, rock units of particular interest occur in the Seve Nappe Complex (SNC) of the so-called Middle Allochthon and include granulite facies migmatites (locally with evidence of ultra-high pressures) and amphibolite facies gneisses and mafic rocks. This complex overlies greenschist facies metasedimentary rocks of the dolerite-intruded Sarv Nappes and underlying, lower grade Jamtlandian Nappes (Lower Allochthon). Reflection seismic profiles have been an important component in the activities to image the subsurface structure in the area. Subhorizontal reflections in the upper 1-2 km are underlain and interlayered with strong west- to northwest-dipping reflections, suggesting significant east-vergent thrusting. Two 2.5 km deep fully cored boreholes are a major component of the project, which will improve our understanding of the subsurface structure and tectonic history of the area. Borehole COSC-1 (IGSN: http://hdl.handle.net/10273/ICDP5054EEW1001), drilled in the summer of 2014, targeted the subduction-related Seve Nappe Complex and the contact with the underlying allochthon. The COSC-2 borehole will be located further east and will investigate the lower grade, mainly Cambro-Silurian rocks of the Lower Allochthon, the Jamtlandian decollement, and penetrate into the crystalline basement rocks to identify the source of some of the northwest-dipping reflections. A series of high-resolution seismic profiles have been acquired along a composite ca

  18. Super-Nyquist-WDM transmission over 7,326-km seven-core fiber with capacity-distance product of 1.03 Exabit/s · km.

    PubMed

    Igarashi, Koji; Tsuritani, Takehiro; Morita, Itsuro; Tsuchida, Yukihiro; Maeda, Koichi; Tadakuma, Masateru; Saito, Tsunetoshi; Watanabe, Kengo; Imamura, Katsunori; Sugizaki, Ryuichi; Suzuki, Masatoshi

    2014-01-27

    We show super-Nyquist-WDM transmission technique, where optical signals with duobinary-pulse shaping can be wavelength-multiplexed with frequency spacing of below baudrate. Duobinary-pulse shaping can reduce the signal bandwidth to be a half of baudrate while controlling inter-symbol interference can be compensated by the maximum likelihood sequence estimation in a receiver. First, we experimentally evaluate crosstalk characteristics as a function of channel spacing between the dual-channel DP-QPSK signals with duobinary-pulse shaping. As a result, the crosstalk penalty can be almost negligible as far as the ratio of baudrate to frequency spacing is maintained to be less than 1.20. Next, we demonstrate 140.7-Tbit/s, 7,326-km transmission of 7 × 201-channel 25-GHz-spaced super-Nyquist-WDM 100-Gbit/s optical signals using seven-core fiber and full C-band seven-core EDFAs. To the best of our knowledge, this is one of the first reports of high-capacity transmission experiments with capacity-distance product in excess of 1 Exabit/s · km.

  19. On the nature of lithologic contacts in the Gabriel Peak tectonic belt, north Cascades, Washington: Decreasing probability of large-scale (> 4 km) net displacement of the Skagit core relative to the Gabriel Peak Orthogneiss

    SciTech Connect

    Kriens, B.J.; Chappelear, D.F. . Dept. of Earth Sciences)

    1993-04-01

    Previous interpretations of the NW-striking contact zone between the Gabriel Peak Orthogneiss and undifferentiated Skagit Complex have suggested that there is a continuous NW-striking shear zone present throughout its ca. 90 km map length, and that there is the possibility of large displacement between the two units. The authors' detailed mapping of the northern half of the contact zone (from Red Mtn. to Rainbow Lake) suggests that a continuous shear zone does not exist, and that the amount of displacement in the contact zone is therefore limited. In their map area, the contact zone is characterized by a relatively thin, discontinuous septum of kyanite-bearing metasediments (Hozameen-Methow protolith) sandwiched between compositionally heterogeneous orthogneisses of the Skagit Complex on the W and Gabriel Peak Orthogneiss on the E. The southern 35 km of the area contains ductilely deformed intrusive contacts between all units: dikes and xenoliths were found in the vicinity of the main unit contacts, and the authors have found no pervasive fabric asymmetries or large (> 2 m-long) brittle faults at the main contacts or within the units. However, the northern 10 km of the area (the Red Mtn. area) contains a 1 m-thick band of mylonite, modified by a brittle fault, at the metasedimentary septum-Gabriel Peak Orthogneiss contact. Minimum strike length of both secondary structures is about 2.5 km. Since these structures die out within 5 km to the S and 10 km to the N, the amount of net displacement attributable to these structures must be small (probably no more than 2--4 km). In addition, the brittle fault cuts into the metasedimentary septum near both ends of the septum here, and since this septum is no larger than about 3 km x 1 km in area, the authors feel that displacement on the brittle fault is further constrained to be less than 1--2 km.

  20. 48 CFR 970.1504-1-2 - Fee policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Contracting by Negotiation 970.1504-1-2 Fee policy. (a) DOE management and operating contractors may be paid a fee in accordance with the requirements of this subsection... available fee should reflect the financial risk assumed by the contractor. (2) It is the policy of...

  1. 48 CFR 970.1504-1-2 - Fee policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Contracting by Negotiation 970.1504-1-2 Fee policy. (a) DOE management and operating contractors may be paid a fee in accordance with the requirements of this subsection... available fee should reflect the financial risk assumed by the contractor. (2) It is the policy of...

  2. MAPK Signaling and ERK1/2 bistability in Asthma

    PubMed Central

    Alam, Rafeul; Gorska, Magdalena M.

    2010-01-01

    Mitogen-activated protein kinases (MAPK) integrate signals from numerous receptors and translate these signals into cell functions. MAPKs are critical for immune cell metabolism, migration, production of pro-inflammatory mediators, survival, and differentiation. We provide a concise review of the involvement of MAPK in important cells of the immune system. Certain cell functions e.g. production of pro-inflammatory mediators resolve quickly and may require a transient MAPK activation, other processes such as cell differentiation and long-term survival may require persistent MAPK signal. The persistent MAPK signal is frequently a consequence of positive feedback loops or double negative feedback loops which perpetuate the signal after removal of an external cell stimulus. This self-perpetuated activation of a signaling circuit is a manifestation of its bistability. Bistable systems can exist in “on” and “off” states and both states are stable. We have demonstrated the existence of self-perpetuated activation mechanism for ERK1/2 in bronchial epithelial cells. This sustained activation of ERK1/2 supports long-term survival of these cells and primes them for cytokine transcription. ERK1/2 bistability arises from repetitive stimulation of the cell. The repeated stimulation (e.g. repeated viral infection or repeated allergen exposure) seems to be a common theme in asthma and other chronic illnesses. We thus hypothesize that the self-perpetuated ERK1/2 signal plays an important role in the pathogenesis of asthma. PMID:21121982

  3. Indeno[1,2,3-cd]pyrene

    Integrated Risk Information System (IRIS)

    Indeno [ 1,2,3 - cd ] pyrene ; CASRN 193 - 39 - 5 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Nonc

  4. 14 CFR 1.2 - Abbreviations and symbols.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Federal Register citations affecting § 1.2, see the List of CFR Sections Affected, which appears in the...) means nondirectional beacon (automatic direction finder). NM means nautical mile. NOPAC means North... Tracking and Reporting System. RAIL means runway alignment indicator light system. RBN means radio...

  5. 14 CFR 1.2 - Abbreviations and symbols.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Federal Register citations affecting § 1.2, see the List of CFR Sections Affected, which appears in the...) means nondirectional beacon (automatic direction finder). NM means nautical mile. NOPAC means North... Tracking and Reporting System. RAIL means runway alignment indicator light system. RBN means radio...

  6. Determination of Ethane-1,2-diamine in Inert Complexes.

    ERIC Educational Resources Information Center

    Searle, Graeme H.

    1985-01-01

    Describes a procedure for determining ethane-1,2-diamine (EN) which is generally applicable for inert or labile complexes or for EN in its salts, although it cannot be used directly with ammonium or coordinated ammonia. It gives results with five percent accuracy or better and requires less than one hour laboratory time. (JN)

  7. The Addition of Bromine to 1,2-Diphenylethene

    ERIC Educational Resources Information Center

    Amburgey-Peters, Judith C.; Haynes, Leroy W.

    2005-01-01

    The bromination of 1,2-diphenylethene, using a variety of solvents and brominating agents, can be used in both introductory and advanced organic chemistry courses. The reactions can be used to illustrate the effects of changing solvents and reagents, as well as to reveal interesting aspects of organic reaction mechanisms.

  8. Graphing Online Searches with Lotus 1-2-3.

    ERIC Educational Resources Information Center

    Persson, Olle

    1986-01-01

    This article illustrates how Lotus 1-2-3 software can be used to create graphs using downloaded online searches as raw material, notes most commands applied, and outlines three required steps: downloading, importing the downloading file into the worksheet, and making graphs. An example in bibliometrics and sample graphs are included. (EJS)

  9. Multiplex detection of Solenopsis invicta viruses -1, -2, and -3

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A multiplex polymerase chain reaction (PCR) method was developed to detect simultaneously Solenopsis invicta viruses -1, -2, and -3 in their host, the red imported fire ant, Solenopsis invicta. cDNA synthesis was conducted in a single reaction containing three oligonucleotide primers specific for ...

  10. 36 CFR 1.2 - Applicability and scope.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 1.2 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL... subject to the ebb and flow of the tide and up to the ordinary high water mark in other places) and... management plans, or in emergency operations involving threats to life, property, or park resources. (e)...

  11. 36 CFR 1.2 - Applicability and scope.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 1.2 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL... subject to the ebb and flow of the tide and up to the ordinary high water mark in other places) and... management plans, or in emergency operations involving threats to life, property, or park resources. (e)...

  12. 36 CFR 1.2 - Applicability and scope.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 1.2 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL... subject to the ebb and flow of the tide and up to the ordinary high water mark in other places) and... management plans, or in emergency operations involving threats to life, property, or park resources. (e)...

  13. 36 CFR 1.2 - Applicability and scope.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 1.2 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR GENERAL... subject to the ebb and flow of the tide and up to the ordinary high water mark in other places) and... management plans, or in emergency operations involving threats to life, property, or park resources. (e)...

  14. 1,2-shifts of hydrogen atoms in aryl radicals

    SciTech Connect

    Brooks, M.A.; Scott, L.T.

    1999-06-16

    An energy barrier on the order of 60 kcal/mol is predicted for the 1,2-shift of hydrogen atoms in aryl radicals. Such rearrangements are, therefore, not expected to occur under ordinary laboratory conditions, but they should be prevalent in the aryl radicals formed during combustion, flash vacuum pyrolysis, and other high-temperature gas-phase processes. As a demonstration of this rearrangement, the 2-benzo[c]phenanthryl radical (1) was generated by flash vacuum pyrolysis of the corresponding aryl bromide. A 1,2-shift of hydrogen out of the sterically congested cover region of 1, followed by cyclization and rearomatization of the resulting radical, is proposed to explain the observation of benzo[ghi]fluoranthene as the dominant monomeric product formed. Under the same conditions, [1,3,4,5-{sup 2}H{sub 4}]-2-bromobenzo[c]phenanthrene gives [1,2,3,4-{sup 2}H{sub 4}]-benzo[ghi]fluoranthene as the dominant monomeric product, in accord with the expectation of a deuterium atom 1,2-shift.

  15. Di(hydroxyphenyl)- 1,2,4-triazole monomers

    NASA Technical Reports Server (NTRS)

    Connell, John W. (Inventor); Hergenrother, Paul M. (Inventor); Wolf, Peter (Inventor)

    1993-01-01

    The di(hydroxyphenyl)- 1,2,4-triazole monomers were first synthesized by reacting bis (4-hydroxyphenyl) hydrazide with aniline hydrochloride at 250 C in the melt and also by reacting 1,3 or 1,4-bis- (4-hydroxyphenyl)- phenylene- dihydrazide with 2 moles of aniline hydrochloride in the melt. Purification of the di(hydroxyphenyl)- 1,2,4-triazole monomers was accomplished by recrystallization. Poly (1,2,4-triazoles) (PT) were prepared by the aromatic nucleophilic displacement reaction of di(hydroxyphenyl)- 1,2,4-triazole monomers with activated aromatic dihalides or activated aromatic dinitro compounds. The reactions were carried out in polar aprotic solvents such as sulfolane or diphenylsulfone using alkali metal bases such as potassium carbonate at elevated temperatures under nitrogen. This synthetic route has provided high molecular weight PT of new chemical structure, is economically and synthetically more favorable than other routes, and allows for facile chemical structure variation due to the availability of a large variety of activated aromatic dihalides.

  16. 2. Threefourths view of bridge showing truss spans 1, 2, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Three-fourths view of bridge showing truss spans 1, 2, and 3 timber approach on south end, and relation of bridge to stream an adjoining terrain - Bridge No. 33.3, Spanning Elk River at Milepost JC-33.3, Fayetteville, Lincoln County, TN

  17. LOTUS 1-2-3 Macros for Library Applications.

    ERIC Educational Resources Information Center

    Howden, Norman

    1987-01-01

    Describes LOTUS 1-2-3, an advanced spreadsheet with database and text manipulation functions that can be used with microcomputers by librarians to provide customized calculation and data acquisition tools. Macro commands and the menu system are discussed, and an example is given of an invoice procedure. (Author/LRW)

  18. AmeriFlux BR-Sa1 Santarem-Km67-Primary Forest

    SciTech Connect

    Saleska, Scott

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site BR-Sa1 Santarem-Km67-Primary Forest. Site Description - The LBA Tapajos KM67 Mature Forest site is located in the Tapajos National Forest, a 450,000 ha closed-canopy upland forest in Amazonian Brazil. Bounded by the Tapajos River in the west and highway BR-163 to the east, the tower is located on a flat plateau (or planalto) that extends up to 150 km to the north, south, and east. Within the confines of the National Forest, anthropogenic disturbances are limited to a few small hunting trails. The surrounding stand is classified as primary or "old-growth"" predominantly by its uneven age distribution, emergent trees, numerous epiphytes and abundant large logs. In 2007 falling trees hit the tower guy wires rendering all instrumentation in-operational. After a complete restoration tower measurements resumed in August of 2008.

  19. Relative Density Anomalies Below 200 km as Observed by Aerodynamic Drag on Orbiting Rocket Bodies

    NASA Astrophysics Data System (ADS)

    Pilinski, M.; Argrow, B.; Palo, S. E.

    2011-12-01

    We examine the geomagnetic latitude and local solar time dependence of density anomalies as observed by rocket bodies in highly eccentric orbits. Density anomalies are estimated by analyzing the fitted ballistic coefficients produced by the Air Force Space Command's High Accuracy Satellite Drag Model. Particularly, observations of rocket bodies with very low perigee altitudes allow for the examination of density anomalies between 105 km and 200 km altitudes. We evaluate the ability to extract coherent geophysical signals from this data set. Finally, a statistical comparison is made between the low altitude density anomalies and those observed by the CHAMP and GRACE satellites above 300 km. In particular, we search for density enhancements which may be associated with the dayside cusp region.

  20. Seismic evidence against a mantle chemical discontinuity near 660 km depth beneath Izu-Bonin

    NASA Astrophysics Data System (ADS)

    Castle, John C.; Creager, Kenneth C.

    We analyze P-wave codas from 12 deep Izu-Bonin earthquakes recorded by hundreds of Western United States seismograph stations for evidence of small-amplitude phases caused by near-source mantle discontinuities. For nearly every event, the dominant phase in the coda is the result of an S-to-P conversion from a nearly horizontal discontinuity ranging in depth from 650 to 690 km. This is interpreted as a thermally depressed spinel to perovskite and magnesiowüstite phase transition. If the 660-km seismic discontinuity is also associated with a change in chemistry, it would be dynamically depressed by a subducting slab. We consistently see that there is no nearly horizontal discontinuity between 700 and 1000 km with shear wave velocity contrast exceeding 1%; this observation places constraints on the properties of a postulated chemical discontinuity separating the upper and lower mantles.

  1. Gravity wave and tidal structures between 60 and 140 km inferred from space shuttle reentry data

    SciTech Connect

    Fritts, D.C. ); Dingyi Wang ); Blanchard, R.C. )

    1993-03-15

    This study presents an analysis of density measurements made using high-resolution accelerometers aboard several space shuttles at altitudes from 60 to 140 km during reentry into the earth's atmosphere. The observed density fluctuations are interpreted in terms of gravity waves and tides and provide evidence of the importance of such motions well into the thermosphere. Height profiles of fractional density variance reveal that wave amplitudes increase at a rate consistent with observations at lower levels up to [approximately]90 km. The rate of amplitude growth decreases at greater heights, however, and appears to cease above [approximately]110 km. Wave amplitudes are nevertheless large at these heights and suggest that gravity waves may play an important role in forcing of the lower thermosphere.

  2. Effects of radiant heat exposure on pacing pattern during a 15-km cycling time trial.

    PubMed

    Levels, Koen; de Koning, Jos; Broekhuijzen, Iris; Zwaan, Tamara; Foster, Carl; Daanen, Hein

    2014-01-01

    The goal of this study was to investigate the effects of different durations of skin temperature manipulation on pacing patterns and performance during a 15-km cycling time trial. Nineteen well-trained men completed three 15-km cycling time trials in 18 °C and 50% relative humidity with 4.5-km (short-heat), 9.0-km (long-heat) or without (control) radiant heat exposure applied by infrared heaters after 1.5 km in the time trial. During the time trials, power output, mean skin temperature, rectal temperature, heart rate and rating of perceived exertion were assessed. The radiant heat exposure resulted in higher mean skin temperature during the time trial for short-heat (35.0 ± 0.6 °C) and long-heat (35.3 ± 0.5 °C) than for control (32.5 ± 1.0 °C; P < 0.001), whereas rectal temperature was similar (P = 0.55). The mean power output was less for short-heat (273 ± 8 W; P = 0.001) and long-heat (271 ± 9 W; P = 0.02) than for control (287 ± 7 W), but pacing patterns did not differ (P = 0.55). Heart rate was greatest in control (177 ± 9 beats · min(-1); P < 0.001), whereas the rating of perceived exertion remained similar. We concluded that a radiant heat exposure and associated higher skin temperature reduced overall performance, but did not modify pacing pattern during a 15-km cycling time trial, regardless of the duration of the exposure.

  3. Cooling vest worn during active warm-up improves 5-km run performance in the heat.

    PubMed

    Arngrïmsson, Sigurbjörn A; Petitt, Darby S; Stueck, Matthew G; Jorgensen, Dennis K; Cureton, Kirk J

    2004-05-01

    We investigated whether a cooling vest worn during an active warm-up enhances 5-km run time in the heat. Seventeen competitive runners (9 men, maximal oxygen uptake = 66.7 +/- 5.9 ml x kg(-1) x min(-1); 8 women, maximal oxygen uptake = 58.0 +/- 3.2 ml x kg(-1) x min(-1)) completed two simulated 5-km runs on a treadmill after a 38-min active warm-up during which they wore either a T-shirt (C) or a vest filled with ice (V) in a hot, humid environment (32 degrees C, 50% relative humidity). Wearing the cooling vest during warm-up significantly (P < 0.05) blunted increases in body temperature, heart rate (HR), and perception of thermal discomfort during warm-up compared with control. At the start of the 5-km run, esophageal, rectal, mean skin, and mean body temperatures averaged 0.3, 0.2, 1.8, and 0.4 degrees C lower; HR averaged 11 beats/min lower; and perception of thermal discomfort (5-point scale) averaged 0.6 point lower in V than C. Most of these differences were eliminated during the first 3.2 km of the run, and these variables were not different at the end. The 5-km run time was significantly lower (P < 0.05) by 13 s in V than C, with a faster pace most evident during the last two-thirds of the run. We conclude that a cooling vest worn during active warm-up by track athletes enhances 5-km run performance in the heat. Reduced thermal and cardiovascular strain and perception of thermal discomfort in the early portion of the run appear to permit a faster pace later in the run.

  4. On the origin of 150-km echoes: Recent observational results and current understanding

    NASA Astrophysics Data System (ADS)

    Patra, Amit

    2012-07-01

    Discovered nearly 45 years ago, the so-called 150-km echoing phenomenon continues to be a puzzle. These are the coherent radar echoes coming from the height region of 140-180 km during daytime and are of special interest to the ionospheric scientists since they are very useful means for estimating the daytime electric fields, a crucial parameter for studying daytime electrodynamics and plasma physics, and can be observed by radar with moderate sensitivity. Although the 150-km echoes are being regularly used for studying low latitude electrodynamics, it is a bit awkward using them in the scientific work without knowing their origin. This paper is meant to present and discuss new results obtained from Gadanki (13.5o N, 79.2o E, mag. lat. 6.5o N), India to elucidate the underlying physical processes, not considered before. Two new findings, one obtained during the passage of a solar eclipse and another linked with the intermediate layer type descending properties of 150-km echoes, clearly indicate the role of electron density gradient in generating the irregularities responsible for the 150-km radar echoes, not envisioned before. Given the fact that Gadanki is located at magnetically low latitude, it is proposed that the descending echoing layers are produced by interchange instability on the gradient of daytime descending ion layer formed by meridional wind shear associated with tidal/gravity waves quite similar to that observed during nighttime. Comparative anatomy of daytime 150-km echoes and nighttime intermediate layer echoes will also be presented and discussed in an effort to have a deeper understanding on the underlying instability processes.

  5. Appraising the reliability of converted wavefield imaging: application to USArray imaging of the 410-km discontinuity

    NASA Astrophysics Data System (ADS)

    Liu, Xin; Pavlis, Gary L.

    2013-03-01

    We develop a generic method to appraise the reliability of wavefield imaging methods and use it to validate some novel observations on the 410-km discontinuity. The core concept of the error appraisal method is to produce a simulated data set that replicates the geometry of the real data. Here we implemented two simulation methods: (1) flat layer primary P to S conversions, and (2) a point source scattering model for P to S conversion data based on the Born approximation and ray theory propagators. We show how the approach can be extended for any simulation algorithm. We apply this new approach to appraise recent results using a 3-D, three-component P to S conversion imaging method applied to data collected by the USArray. Multiple metrics show that the amplitude of P to S converted energy scattered from the 410-km discontinuity varies by 18 dB with a systematically lower amplitude in an irregular band running from Idaho through northern Arizona. In addition, we observe strong lateral changes in the ratio of amplitudes recovered on the radial versus the transverse component. We compute point resolution functions and a checkerboard test to demonstrate we can reliably recover relative amplitudes with a lateral scale of the order of 200 km and a vertical scale of approximately 10 km. Irregular coverage locally distorts the amplitudes recovered in the checkerboard, but a 156 km scale checkerboard pattern is recovered. Flat layer simulations show we can recover relative amplitudes to within a range of 1 dB and the reconstructed transverse to radial amplitude is everywhere less than 0.1. A model with north-south oriented ridges with a 3° wavelength and 12.5 km amplitude shows of the order of ±6 dB amplitude variations and small, but clear correlation of the transverse/radial amplitude ratio topography in the model. Finally, we model the 410-km discontinuity as a rough surface characterized by variations in amplitude and depth derived from the USArray data. The rough

  6. One kilometer (1 km) electric solar wind sail tether produced automatically.

    PubMed

    Seppänen, Henri; Rauhala, Timo; Kiprich, Sergiy; Ukkonen, Jukka; Simonsson, Martin; Kurppa, Risto; Janhunen, Pekka; Hæggström, Edward

    2013-09-01

    We produced a 1 km continuous piece of multifilament electric solar wind sail tether of μm-diameter aluminum wires using a custom made automatic tether factory. The tether comprising 90,704 bonds between 25 and 50 μm diameter wires is reeled onto a metal reel. The total mass of 1 km tether is 10 g. We reached a production rate of 70 m/24 h and a quality level of 1‰ loose bonds and 2‰ rebonded ones. We thus demonstrated that production of long electric solar wind sail tethers is possible and practical.

  7. Lunar thermal regime to 300 km. [in crust and upper mantle

    NASA Technical Reports Server (NTRS)

    Keihm, S. J.; Langseth, M. G.

    1977-01-01

    Coupling of the global heat flow, crustal heat source enrichment, thermal conductivity, and temperature in the crust and upper mantle of the moon is examined. A steady-state moon in which conductive heat transfer dominates is assumed. Heat-flow measurements from the Apollo 15 and 17 missions and gamma-ray mapping of thorium conducted by the Apollo 15 and 16 missions provide data for the study of the lunar thermal regime. Temperatures in the range of 1100 to 1600 K are found for the 300-km depth level. In the upper mantle, temperature gradients are in the range of 1.8 to 3.2 K/km.

  8. Configuration Management (CM) Support for KM Processes at NASA/Johnson Space Center (JSC)

    NASA Technical Reports Server (NTRS)

    Cioletti, Louis

    2010-01-01

    Collection and processing of information are critical aspects of every business activity from raw data to information to an executable decision. Configuration Management (CM) supports KM practices through its automated business practices and its integrated operations within the organization. This presentation delivers an overview of JSC/Space Life Sciences Directorate (SLSD) and its methods to encourage innovation through collaboration and participation. Specifically, this presentation will illustrate how SLSD CM creates an embedded KM activity with an established IT platform to control and update baselines, requirements, documents, schedules, budgets, while tracking changes essentially managing critical knowledge elements.

  9. Atmospheric temperature measurements at altitudes of 5-30  km with a double-grating-based pure rotational Raman lidar.

    PubMed

    Jia, Jingyu; Yi, Fan

    2014-08-20

    A pure rotational Raman (PRR) lidar based on a second-harmonic generation Nd:YAG laser is built for measuring the atmospheric temperature at altitudes of 5-30 km. A double-grating polychromator is designed to extract the wanted PRR signals and suppress the elastically backscattered light. Measured examples present the overall lidar performance. For the 1-h integrated lidar temperature profiles, the 1σ statistical uncertainty is less than 0.5 K up to ∼17  km, while it does not exceed 2 K at altitudes of 17-26.3 km. Based on 38 nights of high-quality lidar temperature data, the temperature variability is studied. It is found that the variability differs between the nights with inversion layer and those without it. On the nights without inversion layer, the local hour-to-hour temperature variability was mostly less than 1 K at altitudes of 5-17 km. At altitudes of 17-23 km, it grew to 1.2-2.4 K. On the nights with inversion layer, in the middle and upper troposphere, the significant variability was found to occur only at the inversion-layer altitudes. At other tropospheric altitudes off the inversion layer, the variability was generally less than 1 K. The statistical results indicate that the temperature variability mostly was stronger in the presence of inversion layer than in its absence.

  10. System Wide Information Management (SWIM)

    NASA Technical Reports Server (NTRS)

    Hritz, Mike; McGowan, Shirley; Ramos, Cal

    2004-01-01

    This viewgraph presentation lists questions regarding the implementation of System Wide Information Management (SWIM). Some of the questions concern policy issues and strategies, technology issues and strategies, or transition issues and strategies.

  11. World Wide Web telemedicine system

    NASA Astrophysics Data System (ADS)

    Li, Xin; Valentino, Daniel J.; So, George J.; Lufkin, Robert B.; Taira, Ricky K.

    1996-05-01

    We have designed a teleradiology and telemedicine architecture over the World-Wide Web using current HIS, RIS and PACS. Our implementation allows remote access to hypermedia medical record and automatic management of interactive communications between referring physician and consultants. Security and privacy issues are also discussed. Its successful use in a telemedicine trial to China involving hundreds of doctors has shown the potential trend of telemedicine over the World-Wide Web.

  12. Fabrication and characterization of relaxor ferroelectric PbFe1/2Ta1/2O3 thin film: A comparison with ceramics

    NASA Astrophysics Data System (ADS)

    Martínez V, R.; Kumar, Ashok; Sanchez, Dilsom A.; Palai, R.; Katiyar, R. S.

    2010-10-01

    Highly oriented Pb(Fe1/2Ta1/2)O3 (PFT) film is fabricated on conducting La0.67Sr0.33CoO3 coated (100) MgO substrate using pulsed laser deposition technique. The x-ray diffraction pattern shows single phase compound having preferential orientation along (100) plane. Surface topography of the film indicates homogeneous distribution of grains with an average grain size ˜55 nm. Broad dielectric dispersion, high dielectric diffusivity, and moderate dielectric loss are observed in the vicinity of wide range of temperatures and frequencies. A reasonably good shift in dielectric maximum temperature (˜30 K) is observed from 1 to 500 kHz suggests relaxor nature of film in this frequency range. At the same time, diffuse dielectric dispersion is seen above 500 kHz indicating diffuse ferroelectric phase transition. Dielectric data fallows the nonlinear Vogel-Fulcher relation below 500 kHz applied frequency which support the relaxor nature of PFT film. The ferroelectric hysteresis loop and butterfly loop show well defined saturated loop below freezing temperature (Tf) (˜150 K). A large shift in dielectric maximum temperature (Tm), i.e., around 75 K is observed compared to bulk counterpart that may be due to misfit strain across substrate-bottom electrode-film interface and in plane compressive strain in the film.

  13. Coadsorption of organic compounds and water vapor on BPL activated carbon: 2. 1,1,2-trichloro-1,2,2-trifluoroethane and dichloromethane

    SciTech Connect

    Eissmann, R.N.; LeVan, M.D. . Dept. of Chemical Engineering)

    1993-11-01

    A novel volumetric apparatus is used to measure equilibria for mixed vapors of halocarbons and water coadsorbed on BPL activated carbon. Pure-component 1,1,2-trichloro-1,2,2-trifluoroethane (CFC 113) and dichloromethane (methylene chloride) isotherms are obtained at 0, 25, 50, 75, and 100 C over wide ranges of pressure. A separate isotherm measured for CFC-113 at 50 C indicates the presence of pure component hysteresis in the mesopore structure of the activated carbon at high halocarbon loadings. Mixture equilibria are measured for CFC-113/water systems at 25 and 100 C and for dichloromethane/water systems at 25 C. All components exhibit hysteresis, and the halocarbon partial pressure increases as the water loading is increased at constant halocarbon loading. Results for halocarbon/water mixtures together with previous results for hydrocarbon/water mixtures show that the apparent total pore volume filled near saturation is dependent on the adsorption temperature and the solubility of the organic compound in water.

  14. San Andres Rift, Nicaraguan Shelf: A 346-Km-Long, North-South Rift Zone Actively Extending the Interior of the "Stable" Caribbean Plate

    NASA Astrophysics Data System (ADS)

    Carvajal, L. C.; Mann, P.

    2015-12-01

    The San Andres rift (SAR) is an active, 015°-trending, bathymetric and structural rift basin that extends for 346 km across the Nicaraguan platform and varies in bathymetric width from 11-27 km and in water depth from 1,250 to 2,500 m. We used four 2D regional seismic lines tied to two offshore, industry wells located west of the SAR on the Nicaraguan platform to map normal faults, transfer faults, and possibly volcanic features with the rift. The Colombian islands of San Andres (26 km2) and Providencia (17 km2) are footwall uplifts along west-dipping, normal fault bounding the eastern margin of the rift. Mapping indicates the pre-rift section is Late Cretaceous to Oligocene in age and that the onset of rifting began in the early to middle Miocene as shown by wedging of the Miocene and younger sedimentary fill controlled by north-south-striking normal faults. Structural restorations at two locations across the rift shows that the basin opened mainly by dip-slip fault motions producing a total, east-west extension of 18 km in the north and 15 km in the south. Structural restoration shows the rift formed on a 37-km-wide, elongate basement high - possibly of late Cretaceous, volcanic origin and related to the Caribbean large igneous province. Previous workers have noted that the SAR is associated with province of Pliocene to Quaternary seamounts and volcanoes which range from non-alkaline to mildly alkaline, including volcanic rocks on Providencia described as andesites and rhyolites. The SAR forms one of the few recognizable belts of recorded seismicity within the Caribbean plate. The origin of the SAR is related to Miocene and younger left-lateral displacement along the Pedro Banks fault to the north and the southwestern Hess fault to the south. We propose that the amount of left-lateral displacement that created the rift is equivalent to the amount of extension that formed it: 18-20 km.

  15. Sporothrix schenckii (sensu strict S. globosa) mating type 1-2 (MAT1-2) gene.

    PubMed

    Kano, Rui; Anzawa, Kazushi; Mochizuki, Takashi; Nishimoto, Katsutaro; Hiruma, Masataro; Kamata, Hiroshi; Hasegawa, Atsuhiko

    2013-09-01

    Sporotix schenckii is a pathogenic fungus that causes human and animal sporotrichosis, and based on morphology of the sessile conidia and molecular analysis, it was recently recognized as a species complex comprising at least the following six sibling species: S. albicans, S. brasiliensis, S. globosa, S. luriei, S. mexicana and S. schenckii. However, apart from S. schenckii sensu strict, only S. brasiliensis, S. globosa and S. luriei are associated with human and animal infection. S. globosa has been most commonly isolated in Asia, Europe and the USA; therefore, molecular epidemiological study for S. globosa is important in relation to human sporotrichosis in Japan. To the best of our knowledge, this is the first study to determine the mating type 1-2 (MAT1-2) gene of Sporothrix schenckii with the aim of understanding the taxonomy of the genus Sporothrix. The MAT1-2 gene (1618 bp) encodes a protein sequence of 198 amino acids. Reverse transcription polymerase chain reaction analysis also detected MAT1-2 gene mRNA expression in all of the S. schenckii strains examined, indicating that this gene is expressed in S. schenckii cells. Phylogenetic analysis of the MAT1-2 gene fragments of Ophiostoma himal-ulmi, O. novo-ulmi, O. ulmi and S. schenckii indicated that these isolates could be classified into four clusters. MAT1-1 gene-specific polymerase chain reaction was positive in 15 isolates, but negative in four human isolates and one feline isolate.

  16. An upper limit to the product of NO and O densities from 105 to 120 km

    NASA Technical Reports Server (NTRS)

    Donahue, T. M.

    1974-01-01

    From the Ogo 6 horizon-scanning-photometer data a useful upper limit can be set to the radiance of nightglow in the O-NO afterglow continuum above 105 km. The upper limit is a factor of about 5 less than the product of observed NO densities and Jacchia (1971) O model densities.

  17. MISR 17.6 KM Gridded Cloud Motion Vectors: Overview and Assessment

    NASA Technical Reports Server (NTRS)

    Mueller, Kevin; Garay, Michael; Moroney, Catherine; Jovanovic, Veljko

    2012-01-01

    The MISR (Multi-angle Imaging SpectroRadiometer) instrument on the Terra satellite has been retrieving cloud motion vectors (CMVs) globally and almost continuously since early in 2000. In February 2012 the new MISR Level 2 Cloud product was publicly released, providing cloud motion vectors at 17.6 km resolution with improved accuracy and roughly threefold increased coverage relative to the 70.4 km resolution vectors of the current MISR Level 2 Stereo product (which remains available). MISR retrieves both horizontal cloud motion and height from the apparent displacement due to parallax and movement of cloud features across three visible channel (670nm) camera views over a span of 200 seconds. The retrieval has comparable accuracy to operational atmospheric motion vectors from other current sensors, but holds the additional advantage of global coverage and finer precision height retrieval that is insensitive to radiometric calibration. The MISR mission is expected to continue operation for many more years, possibly until 2019, and Level 2 Cloud has the possibility of being produced with a sensing-to-availability lag of 5 hours. This report compares MISR CMV with collocated motion vectors from arctic rawinsonde sites, and from the GOES and MODISTerra instruments. CMV at heights below 3 km exhibit the smallest differences, as small as 3.3 m/s for MISR and GOES. Clouds above 3 km exhibit larger differences, as large as 8.9 m/s for MISR and MODIS. Typical differences are on the order of 6 m/s.

  18. Effects of a minimalist shoe on running economy and 5-km running performance.

    PubMed

    Fuller, Joel T; Thewlis, Dominic; Tsiros, Margarita D; Brown, Nicholas A T; Buckley, Jonathan D

    2016-09-01

    The purpose of this study was to determine if minimalist shoes improve time trial performance of trained distance runners and if changes in running economy, shoe mass, stride length, stride rate and footfall pattern were related to any difference in performance. Twenty-six trained runners performed three 6-min sub-maximal treadmill runs at 11, 13 and 15 km·h(-1) in minimalist and conventional shoes while running economy, stride length, stride rate and footfall pattern were assessed. They then performed a 5-km time trial. In the minimalist shoe, runners completed the trial in less time (effect size 0.20 ± 0.12), were more economical during sub-maximal running (effect size 0.33 ± 0.14) and decreased stride length (effect size 0.22 ± 0.10) and increased stride rate (effect size 0.22 ± 0.11). All but one runner ran with a rearfoot footfall in the minimalist shoe. Improvements in time trial performance were associated with improvements in running economy at 15 km·h(-1) (r = 0.58), with 79% of the improved economy accounted for by reduced shoe mass (P < 0.05). The results suggest that running in minimalist shoes improves running economy and 5-km running performance.

  19. Hypervelocity impact testing above 10 km/s of advanced orbital debris shields

    SciTech Connect

    Christiansen, E.L.; Crews, J.L.; Kerr, J.H.; Chhabildas, L.C.

    1996-05-01

    NASA has developed enhanced performance shields to improve the protection of spacecraft from orbital debris and meteoroid impacts. One of these enhanced shields includes a blanket of Nextel{trademark} ceramic fabric and Kevlar{trademark} high strength fabric that is positioned midway between an aluminum bumper and the spacecraft pressure wall. As part of the evaluation of this new shielding technology, impact data above 10 km/sec has been obtained by NASA Johnson Space Center (JSC) from the Sandia National Laboratories HVL ({open_quotes}hypervelocity launcher{close_quotes}) and the Southwest Research Institute inhibited shaped charge launcher (ISCL). The HVL launches flyer-plates in the velocity range of 10 to 15 km/s while the ISCL launches hollow cylinders at {approximately}11.5km/s. The {gt}10km/s experiments are complemented by hydrocode analysis and light-gas gun testing at the JSC Hypervelocity Impact Test Facility (HIT-F) to assess the effects of projectile shape on shield performance. Results from the testing and analysis indicate that the Nextel{trademark}/Kevlar{trademark} shield provides superior protection performance compared to an all-aluminum shield alternative. {copyright} {ital 1996 American Institute of Physics.}

  20. SMOS disaggregated soil moisture product at 1 km resolution: processor overview and first validation results

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The SMOS (Soil Moisture and Ocean Salinity) mission provides surface soil moisture (SM) maps at a mean resolution of ~50 km. However, agricultural applications (irrigation, crop monitoring) and some hydrological applications (floods and modeling of small basins) require higher resolution SM...

  1. The Trigger and Data Acquisition System for the KM3NeT-Italia towers

    NASA Astrophysics Data System (ADS)

    Favaro, M.; Chiarusi, T.; Giacomini, F.; Manzali, M.; Margiotta, A.; Pellegrino, C.

    2016-04-01

    KM3NeT-Italia is an INFN project supported with Italian PON fundings for building the core of the Italian node of the KM3NeT neutrino telescope. The detector, made of 700 10'' Optical Modules (OMs) lodged along 8 vertical structures called towers, will be deployed starting from fall 2015 at the KM3NeT-Italy site, about 80 km off Capo Passero, Italy, 3500 m deep. The all data to shore approach is used to reduce the complexity of the submarine detector, demanding for an on-line trigger integrated in the data acquisition system running in the shore station, called TriDAS. Due to the large optical background in the sea from 40K decays and bioluminescence, the throughput from the underwater detector can range up to 30 Gbps. This puts strong constraints on the design and performances of the TriDAS and of the related network infrastructure. In this contribution the technology behind the implementation of the TriDAS infrastructure is reviewed, focusing on the relationship between the various components and their performances. The modular design of the TriDAS, which allows for its scalability up to a larger detector than the 8-tower configuration is also discussed.

  2. KM Critical Success Factors: A Comparison of Perceived Importance Versus Implementation in Malaysian ICT Companies

    ERIC Educational Resources Information Center

    Chong, Siong Choy

    2006-01-01

    Purpose: This research examines the level of perception and implementation of 11 identified knowledge management (KM) success factors and their differences among the information and communication technology (ICT) companies operating in Malaysia. Design/methodology/approach: The survey data was obtained from a study of 427 middle managers from 194…

  3. Magnetic Anomalies of the Fennoscandian Shield on a 2km resolution grid

    NASA Astrophysics Data System (ADS)

    Korhonen, Juha V.; Aaro, Sven; Reidar Skilbrei, Jan; All, Tarmo

    2010-05-01

    Joint magnetic anomaly grid of the Fennoscandian Shield was released 2002, smoothed and used as data for the WDMAM2007. In comparison with MF5 this grid showed superior characteristics to other sets. The data will be released as a 2 km resolution grid for the WDMAM2011 with eventual updates of anomaly levels.

  4. Enabling Grid Computing resources within the KM3NeT computing model

    NASA Astrophysics Data System (ADS)

    Filippidis, Christos

    2016-04-01

    KM3NeT is a future European deep-sea research infrastructure hosting a new generation neutrino detectors that - located at the bottom of the Mediterranean Sea - will open a new window on the universe and answer fundamental questions both in particle physics and astrophysics. International collaborative scientific experiments, like KM3NeT, are generating datasets which are increasing exponentially in both complexity and volume, making their analysis, archival, and sharing one of the grand challenges of the 21st century. These experiments, in their majority, adopt computing models consisting of different Tiers with several computing centres and providing a specific set of services for the different steps of data processing such as detector calibration, simulation and data filtering, reconstruction and analysis. The computing requirements are extremely demanding and, usually, span from serial to multi-parallel or GPU-optimized jobs. The collaborative nature of these experiments demands very frequent WAN data transfers and data sharing among individuals and groups. In order to support the aforementioned demanding computing requirements we enabled Grid Computing resources, operated by EGI, within the KM3NeT computing model. In this study we describe our first advances in this field and the method for the KM3NeT users to utilize the EGI computing resources in a simulation-driven use-case.

  5. Multiplicity of the 660-km discontinuity beneath the Izu-Bonin area

    NASA Astrophysics Data System (ADS)

    Zhou, Yuan-Ze; Yu, Xiang-Wei; Yang, Hui; Zang, Shao-Xian

    2012-05-01

    The relatively simple subducting slab geometry in the Izu-Bonin region provides a valuable opportunity to study the multiplicity of the 660-km discontinuity and the related response of the subducting slab on the discontinuity. Vertical short-period recordings of deep events with simple direct P phases beneath the Izu-Bonin region were retrieved from two seismic networks in the western USA and were used to study the structure of the 660-km discontinuity. After careful selection and pre-processing, 23 events from the networks, forming 32 pairs of event-network records, were processed. Related vespagrams were produced using the N-th root slant stack method for detecting weak down-going SdP phases that were inverted to the related conversion points. From depth histograms and the spatial distribution of the conversion points, there were three clear interfaces at depths of 670, 710 and 730 km. These interfaces were depressed approximately 20-30 km in the northern region. In the southern region, only two layers were identified in the depth histograms, and no obvious layered structure could be observed from the distribution of the conversion points.

  6. Densities inferred from ESA's Venus Express aerobraking campaign at 130 km altitude

    NASA Astrophysics Data System (ADS)

    Bruinsma, Sean; Marty, Jean-Charles; Svedhem, Håkan; Williams, Adam; Mueller-Wodarg, Ingo

    2015-04-01

    In June-July 2014, ESA performed a planned aerobraking campaign with Venus Express to measure neutral densities above 130 km in Venus' atmosphere by means of the engineering accelerometers. To that purpose, the orbit perigee was lowered to approximately 130 km in order to enhance the atmospheric drag effect to the highest tolerable levels for the spacecraft; the accelerometer resolution and precision were not sufficient at higher altitudes. This campaign was requested as part of the Venus Express Atmospheric Drag Experiment (VExADE). A total of 18 orbits (i.e. days) were processed using the attitude quaternions to correctly orient the spacecraft bus and solar arrays in inertial space, which is necessary to accurately compute the exposed surface in the ram direction. The accelerometer data provide good measurements approximately from 130-140 km altitude; the length of the profiles is about 85 seconds, and they are on the early morning side (LST=4.5) at high northern latitude (70°N-82°N). The densities are a factor 2-3 larger than Hedin's VTS-3 thermosphere model, which is consistent with earlier results obtained via classical precise orbit determination at higher altitudes. Wavelike structures with amplitudes of 20% and more are detected, with wavelengths of about 100-500 km. We cannot entirely rule out that these waves are caused by the spacecraft or due to some unknown instrumental effect, but we estimate this probability to be very low.

  7. The possible subduction of continental material to depths greater than 200 km.

    PubMed

    Ye, K; Cong, B; Ye, D

    2000-10-12

    Determining the depth to which continental lithosphere can be subducted into the mantle at convergent plate boundaries is of importance for understanding the long-term growth of supercontinents as well as the dynamic processes that shape such margins. Recent discoveries of coesite and diamond in regional ultrahigh-pressure (UHP) metamorphic rocks has demonstrated that continental material can be subducted to depths of at least 120 km (ref. 1), and subduction to depths of 150-300 km has been inferred from garnet peridotites in orogenic UHP belts based on several indirect observations. But continental subduction to such depths is difficult to trace directly in natural UHP metamorphic crustal rocks by conventional mineralogical and petrological methods because of extensive late-stage recrystallization and the lack of a suitable pressure indicator. It has been predicted from experimental work, however, that solid-state dissolution of pyroxene should occur in garnet at depths greater than 150 km (refs 6-8). Here we report the observation of high concentrations of clinopyroxene, rutile and apatite exsolutions in garnet within eclogites from Yangkou in the Sulu UHP metamorphic belt, China. We interpret these data as resulting from the high-pressure formation of pyroxene solid solutions in subducted continental material. Appropriate conditions for the Na2O concentrations and octahedral silicon observed in these samples are met at depths greater than 200 km. PMID:11048717

  8. Global 4 km resolution monthly gridded Gross Primary Productivity (GPP) data set derived from FLUXNET2015

    DOE Data Explorer

    Kumar, Jitendra; Hoffman, Forrest M.; Hargrove, William W.; Collier, Nathan

    2016-08-01

    This data set contain global gridded surfaces of Gross Primary Productivity (GPP) at 2 arc minute (approximately 4 km) spatial resolution monthly for the period of 2000-2014 derived from FLUXNET2015 (released July 12, 2016) observations using a representativeness based upscaling approach.

  9. [Generalized transduction of plasmid pKM101 by temperate bacteriophage ZF40 of Erwinia carotovora].

    PubMed

    Panshchina, A I; Tovkach, F I

    2007-01-01

    It was shown that temperate bacteriophage ZF40 of Erwinia carotovora can perform generalized transduction of plasmid pKM 101. The antibiotic-resistance marker transfer is coordinated with the fact of cyclic permutation of the phage genom. The presented results create preconditions for further use of bacteriophage ZF40 as a convenient instrument for genetic study of E. carotovora.

  10. A 2-km walking test for assessing the cardiorespiratory fitness of healthy adults.

    PubMed

    Oja, P; Laukkanen, R; Pasanen, M; Tyry, T; Vuori, I

    1991-08-01

    A simple walking test was developed with 159 (females = 80, males = 79) healthy 20-65-year-old subjects. All the subjects first walked the distances of 1.0, 1.5 and 2.0 km on a flat dirt road. Half of the participants were tested in the laboratory for maximal oxygen uptake (VO2max), and the 2-km test was repeated again twice. In a comparison of the three distances, the 2-km test was repeatable, the most preferable subjectively and the most accurate in predicting VO2max. A sex-specific prediction model including walking time, heart rate at the end of the walk, age and body mass index predicted 73-75% of the variance in VO2max (ml.kg-1.min-1) and that with body weight 66-76%, with a standard error of estimate of the order of 9-15% of the mean. The cross-validation of the models yielded reasonable accuracy in obese men and women and in moderately active men, and less accuracy in moderately active women and highly active men. These results suggest that a fast 2-km walk supplemented with simple measurements is a feasible and accurate alternative for determining the cardiorespiratory fitness of healthy adults.

  11. Nanobeacon: A low cost time calibration instrument for the KM3NeT neutrino telescope

    SciTech Connect

    Calvo, David [IFIC. Instituto de Física Corpuscular, CSIC-Universidad de Valencia, C Collaboration: KM3NeT Collaboration

    2014-11-18

    The KM3NeT collaboration aims at the construction of a multi-km3 high-energy neutrino telescope in the Mediterranean Sea consisting of a matrix of pressure resistant glass spheres holding each one a set (31) of small area photomultipliers. The main goal of the telescope is to observe cosmic neutrinos through the Cherenkov light induced in sea water by charged particles produced in neutrino interactions with the surrounding medium. A relative time calibration between photomultipliers of the order of 1 ns is required to achieve an optimal performance. Due to the high volume to be covered by KM3NeT, a cost reduction of the different systems is a priority. To this end a very low price calibration device, the so called Nanobeacon, has been designed and developed. At present one of such devices has already been integrated successfully at the KM3NeT telescope and eight of them in the Nemo Tower Phase II. In this article the main properties and operation of this device are described.

  12. Gm and Km immunoglobulin allotypes in Reindeer Chukchi and Siberian Eskimos.

    PubMed

    Sukernik, R I; Osipova, L P

    1982-01-01

    Blood samples from 403 Reindeer Chukchi of inland Chukotka, and 100 samples from Chaplin Eskimos of the Chukot Peninsula were tested for G 1 m (z,a,x,f), G2m (n), G3m (g,b0,b1,b3,b5,s,t), and Km (1) allotypic determinants. An apparent affinity between the Chukchi and the Eskimos could be inferred from similar frequencies of the two common haplotypes, Gmza;g and Gmza;bst, and from very similar frequencies of the Km1 allele. However, none of the Eskimos had Gmzax;g, though it occurred at a low or moderate frequency in the five Chukchi populations studied. It is assumed that Chukchi can be distinguished from adjoining Eskimos by the same G1m (x) outlier, that has been considered as a taxonomic marker useful in differentiating between Eskimos and American Indians. Comparison of North Asian and North American populations with respect to the array and frequencies of Gm haplotypes and the Km1 allele, supports the hypothesis of a nonrandom distribution of the Gmza;bst and Km1 on both sides of the Bering Strait. PMID:6957376

  13. Analyzing ERK 1/2 signalling and targets.

    PubMed

    Brietz, Alexandra; Schuch, Kristin Verena; Wangorsch, Gaby; Lorenz, Kristina; Dandekar, Thomas

    2016-07-19

    The ERK cascade (e.g. Raf-1) protects the heart from cell death and ischemic injury but can also turn maladaptive. Furthermore, an additional autophosphorylation of ERK2 at Thr188 (Erk1 at Thr208) allows ERK to phosphorylate nuclear targets involved in hypertrophy, stressing this additional phosphorylation as a promising pharmacological target. An in silico model was assembled and setup to reproduce different phosphorylation states of ERK 1/2 and various types of stimuli (hypertrophic versus non-hypertrophic). Synergistic and antagonistic receptor stimuli can be predicted in a semi-quantitative model, simulated time courses were experimentally validated. Furthermore, we detected new targets of ERK 1/2, which possibly contribute to the development of pathological hypertrophy. In addition we modeled further interaction partners involved in the protective and maladaptive cascade. Experimental validation included different gene expression data sets supporting key components and novel interaction partners as well as time courses in chronic heart failure.

  14. Gentisate 1,2-dioxygenase from Haloferax sp. D1227.

    PubMed

    Fu, W; Oriel, P

    1998-11-01

    Gentisate 1,2-dioxygenase from the extreme halophile Haloferax sp. D1227 (Hf. D1227) was purified using a three-step procedure. The enzyme was found to be a homotetramer of 42,000 +/- 1,000 Da subunits, with a native molecular weight of 174,000 +/- 6,000 Da. The optimal salt concentration, temperature, and pH for enzyme activity were 2 M KCl or NaCl, 45 degrees C, and pH 7.2, respectively. The gene encoding Hf. D1227 gentisate 1,2-dioxygenase was cloned, sequenced, and expressed in Haloferax volcanii. The deduced amino acid sequence exhibited a 9.2% excess acidic over basic amino acids typical of halophilic enzymes. Four novel histidine clusters and a possible extradiol dioxygenase fingerprint region were identified. PMID:9827334

  15. Hexamethylenetetramine-4-nitrocatechol-water (1/2/1).

    PubMed

    Chantrapromma, Suchada; Usman, Anwar; Fun, Hoong Kun; Poh, Bo Long; Karalai, Chatchanok

    2002-11-01

    In the title adduct, 1,3,5,7-tetraazatricyclo[3.3.1.1(3,7)]decane-4-nitrobenzene-1,2-diol-water (1/2/1), C(6)H(12)N(4).2C(6)H(5)NO(4).H(2)O, the hexamethylenetetramine molecule acts as an acceptor of intermolecular O-H.N hydrogen-bonding interactions from the water molecule and the hydroxy groups of one of the two symmetry-independent 4-nitrocatechol molecules. The structure is built from molecular layers which are stabilized by three intermolecular O-H.O, two intermolecular O-H.N and four intermolecular C-H.O hydrogen bonds. The layers are further interconnected by one additional intermolecular O-H.N and two intermolecular C-H.O hydrogen bonds.

  16. Efficient synthesis and reactions of 1,2-dipyrrolylethynes

    PubMed Central

    Tanui, Hillary K.; Hao, Erhong; Ihachi, Moses I.; Fronczek, Frank R.; Smith, Kevin M.; Vicente, M. Graça H.

    2011-01-01

    Various dipyrroles possess important motifs for construction of pyrrole-containing pigments. A series of 1,2-dipyrrolylethynes (4a–d) has been efficiently synthesized using an improved one-pot double Sonagashira coupling from trimethylsilylethyne and various 2-iodopyrroles. The resulting 1,2-dipyrrolylethynes were further transformed into novel indolyl-, ethenyl- and carboranyl-dipyrroles (5–7) using the Larock indole synthesis, stereoselective catalytic hydrogenation, or B10H14. Indolyl-dipyrroles were found to selectively bind fluoride ions using one pyrrolic and the indolyl NHs, whereas the carboranyl- and ethenyl-dipyrroles are potentially valuable precursors for the synthesis of porphyrin isomers and expanded pigments. PMID:21822371

  17. Characterization of Methylglyoxal Synthase from Clostridium acetobutylicum ATCC 824 and Its Use in the Formation of 1,2-Propanediol

    PubMed Central

    Huang, Ke-xue; Rudolph, Frederick B.; Bennett, George N.

    1999-01-01

    A gene encoding a putative 150-amino-acid methylglyoxal synthase was identified in Clostridium acetobutylicum ATCC 824. The enzyme was overexpressed in Escherichia coli and purified. Methylglyoxal synthase has a native molecular mass of 60 kDa and an optimum pH of 7.5. The Km and Vmax values for the substrate dihydroxyacetone phosphate were 0.53 mM and 1.56 mmol min−1 μg−1, respectively. When E. coli glycerol dehydrogenase was coexpressed with methylglyoxal synthase in E. coli BL21(DE3), 3.9 mM 1,2-propanediol was produced. PMID:10388730

  18. Performance of Whipple Shields at Impact Velocities above 9 km/s

    NASA Technical Reports Server (NTRS)

    Christiansen, Eric L.; Davis, Bruce A.; Piekutowski, Andrew J.; Poormon, Kevin L.

    2009-01-01

    Whipple shields were first proposed as a means of protecting spacecraft from the impact of micrometeoroids in 1947 [1] and are currently in use as micrometeoroid and orbital debris shields on modern spacecraft. In the intervening years, the function of the thin bumper used to shatter or melt threatening particles has been augmented and enhanced by the use of various types and configurations of intermediate layers of various materials. All shield designs serve to minimize the threat of a spall failure or perforation of the main wall of the spacecraft as a result of the impact of the fragments. With increasing use of Whipple shields, various ballistic limit equations (BLEs) for guiding the design and estimating the performance of shield systems have been developed. Perhaps the best known and most used are the "new" modified Cour-Palais (Christiansen) equations [2]. These equations address the three phases of impact: (1) ballistic (<3 km/s), where the projectile is moving too slowly to fragment and essentially penetrates as an intact projectile; (2) shatter (3 to 7 km/s), where the projectile fragments at impact and forms an expanding cloud of debris fragments; and (3) melt/vaporization (>7 km/s), where the projectile melts or vaporizes at impact. The performance of Whipple shields and the adequacy of the BLEs have been examined for the first two phases using the results of impact tests obtained from two-stage, light-gas gun test firings. Shield performance and the adequacy of the BLEs has not been evaluated in the melt/vaporization phase until now because of the limitations of launchers used to accelerate projectiles with controlled properties to velocities above 7.5 km/s. A three-stage, light-gas gun, developed at the University of Dayton Research Institute (UDRI) [3], is capable of launching small, aluminum spheres to velocities above 9 km/s. This launcher was used to evaluate the ballistic performance of two Whipple shield systems, various thermal protection

  19. Solid-state conversion of (Na1/2Bi1/2)TiO3-BaTiO3-(K1/2Na1/2)NbO3 single crystals and their piezoelectric properties

    NASA Astrophysics Data System (ADS)

    Park, Ji-Hoon; Lee, Ho-Yong; Kang, Suk-Joong L.

    2014-06-01

    Piezoelectric ceramic with a composition of (94 - x)(Na1/2Bi1/2)TiO3-6BaTiO3-x(K1/2Na1/2)NbO3 (NBT-BT-xKNN) is a promising lead-free piezoelectric material for actuator applications because of its giant electric-field-induced strains, which are comparable with that of soft Pb(ZrxTi1-x)O3 (PZT) ceramics. Using the solid-state single crystal growth method, we succeeded in fabricating usable single crystals of NBT-BT-3KNN (6 mm × 6 mm × 8 mm size) with a uniform chemical composition. The room temperature piezoelectric properties of ⟨001⟩, ⟨110⟩, and ⟨111⟩ oriented single crystals were measured. Single crystals showed strong anisotropic strain characteristics. In particular, ⟨001⟩ oriented single crystals had excellent piezoelectric properties with small hysteresis and a high strain of 0.57% at 7 kV/mm. In addition, the fabricated single crystals exhibited a high converse piezoelectric constant, Smax/Emax, of over 1000 pm/V at 4 kV/mm. These values are greater than those reported for any lead-containing and lead-free ceramics and comparable with those of lead-based single crystals. Our investigation demonstrates the solid-state conversion of lead-free single crystals and their practical usability in replacement of lead-based materials.

  20. Aryne 1,2,3-Trifunctionalization with Aryl Allyl Sulfoxides.

    PubMed

    Li, Yuanyuan; Qiu, Dachuan; Gu, Rongrong; Wang, Junli; Shi, Jiarong; Li, Yang

    2016-08-31

    An aryne 1,2,3-trisubstitution with aryl allyl sulfoxides is accomplished, featuring an incorporation of C-S, C-O, and C-C bonds on the consecutive positions of a benzene ring. The reaction condition is mild with broad substrate scope. Preliminary mechanistic study suggests a cascade formal [2 + 2] reaction of aryne with S═O bond, an allyl S → O migration, and a Claisen rearrangement. PMID:27527334

  1. 38. View of DRS 1, 2, and 3 (structure nos. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. View of DRS 1, 2, and 3 (structure nos. 735, 736, and 737) console fault locator for beam power status, radio frequency (RF) and intermediate frequency (IF) fault conditions, RF switches status and TR status. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  2. Foot strike pattern and gait changes during a 161-km ultramarathon.

    PubMed

    Kasmer, Mark E; Wren, Jeremy J; Hoffman, Martin D

    2014-05-01

    Foot strike pattern has not been examined during ultramarathons where fatigue or avoidance of impact might have greater effect on foot strike and other gait parameters than in shorter events. In this study, video analysis from 3 level sites at a 161-km ultramarathon was used to: (a) examine changes in foot strike pattern, stride rate, and stride length; (b) determine if foot strike pattern is related to performance; and (c) ascertain if post-race blood creatine phosphokinase (CK) concentrations differ by foot strike pattern. Rear-foot strike (RFS) prevalence was 79.9, 89.0, and 83.9% at 16.5, 90.3, and 161.1 km, respectively. There was a significant distance effect observed between the 90.3 and 161.1-km site for stride rate (p < 0.05) and across all distances for stride length (p < 0.0001), but stride rate and length were stable among the top 20 finishers. There was no effect (p = 0.3) of foot strike pattern on performance. However, top 20 finishers had greater use (p = 0.02) of a non-RFS pattern at 161.1 km than the remaining finishers. There was a trend toward greater post-race blood CK values among non-RFS runners compared with RFS runners, reaching significance at the 90.3 km site (p < 0.05). Thus, the increased RFS prevalence by race midpoint was likely because of greater muscular demands of non-RFS patterns as supported by the higher post-race blood CK concentrations among non-RFS runners. Faster runners maintained higher stride rates and lengths throughout the race and made greater use of a non-RFS pattern at the end of the race compared with the slower finishers.

  3. Risks from radionuclide migration to groundwater in the Chernobyl 30-km zone.

    PubMed

    Bugai, D A; Waters, R D; Dzhepo, S P; Skal'skij, A S

    1996-07-01

    Remediation of contaminated groundwater in the Chernobyl 30-km evacuation zone is frequently identified as a priority by technical experts and Chernobyl site officials in Ukraine. In order to evaluate the health risk basis for this groundwater remediation, we have estimated both on-site and off-site health risks caused by radionuclide migration to the groundwater and compared these risks with those from exposure to radioactive contamination on the ground surface. A simple and conservative analytical model was developed to assess radionuclide transport to the groundwater from the soil surface contaminated by radioactive fallout. 90Sr, the primary radioactive contaminant of concern for the groundwater-migration exposure pathway, was evaluated in the analysis. The estimated health risk to hypothetical, self-sufficient residents in the 30-km zone is dominated by external and internal irradiation (due primarily to ingestion of agricultural products) from 137Cs, which is present in soils of the 30-km zone in roughly equal proportion with 90Sr. The estimated risk from contaminated groundwater is approximately an order of magnitude lower. Analysis of 90Sr migration via groundwater to surface water and down-river population centers shows that, despite generally unfavorable environmental conditions in the 30-km exclusion zone, radionuclide transport via the groundwater pathway has potential to contribute only marginally to the off-site radiological risk, which is governed by wash-out of radionuclides from the contaminated river flood plain and catchment areas by surface water during spring snowmelt and rains. Health risks due to off-site radionuclide migration via groundwater are below the level requiring application of counter-measures. This analysis implies that, relative to other exposure pathways, there is little current or future health risk basis for the proposed complex and costly groundwater remediation measures in the 30-km zone. Therefore, these activities should

  4. Simulation study of geometric shape factor approach to estimating earth emitted flux densities from wide field-of-view radiation measurements

    NASA Technical Reports Server (NTRS)

    Weaver, W. L.; Green, R. N.

    1980-01-01

    A study was performed on the use of geometric shape factors to estimate earth-emitted flux densities from radiation measurements with wide field-of-view flat-plate radiometers on satellites. Sets of simulated irradiance measurements were computed for unrestricted and restricted field-of-view detectors. In these simulations, the earth radiation field was modeled using data from Nimbus 2 and 3. Geometric shape factors were derived and applied to these data to estimate flux densities on global and zonal scales. For measurements at a satellite altitude of 600 km, estimates of zonal flux density were in error 1.0 to 1.2%, and global flux density errors were less than 0.2%. Estimates with unrestricted field-of-view detectors were about the same for Lambertian and non-Lambertian radiation models, but were affected by satellite altitude. The opposite was found for the restricted field-of-view detectors.

  5. Wide-Field Plate Database

    NASA Astrophysics Data System (ADS)

    Tsvetkov, M. K.; Stavrev, K. Y.; Tsvetkova, K. P.; Semkov, E. H.; Mutatov, A. S.

    The Wide-Field Plate Database (WFPDB) and the possibilities for its application as a research tool in observational astronomy are presented. Currently the WFPDB comprises the descriptive data for 400 000 archival wide field photographic plates obtained with 77 instruments, from a total of 1 850 000 photographs stored in 269 astronomical archives all over the world since the end of last century. The WFPDB is already accessible for the astronomical community, now only in batch mode through user requests sent by e-mail. We are working on on-line interactive access to the data via INTERNET from Sofia and parallel from the Centre de Donnees Astronomiques de Strasbourg. (Initial information can be found on World Wide Web homepage URL http://www.wfpa.acad.bg.) The WFPDB may be useful in studies of a variety of astronomical objects and phenomena, andespecially for long-term investigations of variable objects and for multi-wavelength research. We have analysed the data in the WFPDB in order to derive the overall characteristics of the totality of wide-field observations, such as the sky coverage, the distributions by observation time and date, by spectral band, and by object type. We have also examined the totality of wide-field observations from point of view of their quality, availability and digitisation. The usefulness of the WFPDB is demonstrated by the results of identification and investigation of the photometrical behaviour of optical analogues of gamma-ray bursts.

  6. Generalized transduction of serotype 1/2 and serotype 4b strains of Listeria monocytogenes.

    PubMed

    Hodgson, D A

    2000-01-01

    This is the first report of generalized transduction in the gram-positive, food-borne pathogen Listeria monocytogenes. Bacteriophages were isolated from the environment and from lysogens, or were obtained from other laboratories. Of the 59 bacteriophages tested, 34 proved to be capable of transduction. We exploited the ability of L. monocytogenes to grow at room temperature and isolated bacteriophages that were incapable of growth at 37 degrees C. Transductions at this temperature therefore eliminated transductant killing and lysogeny, as did inclusion of citrate and the use of a low multiplicity of infection. Transducing bacteriophages were found for each of the well-characterized L. monocytogenes strains: EGD, 10403, Mack (serotype1/2a), L028 (serotype 1/2c), Scott A (serotype 4b) and strains from the Jalisco and Halifax, Nova Scotia outbreaks (serotype 4b). P35 (phiLMUP35) is a particularly useful generalized transducing bacteriophage with a wide host range (75% of all serotype 1/2 strains tested). Its disadvantages are that it is small and transduction is relatively infrequent. U153(phiCU-SI153/95) is larger than P35 and transduction frequency increased 100-fold, but it has a very narrow host range. We demonstrated interstrain transduction and used transduction to test linkage between transposon insertions and mutant phenotypes in a variety of strains.

  7. Dielectric Relaxation In Complex Perovskite Sm(Ni1/2Ti1/2)O3

    NASA Astrophysics Data System (ADS)

    Kumar, Nishant; Prasad, S.; Sinha, T. P.

    2011-11-01

    The complex perovskite oxide Samarium nickel titenate, Sm(Ni1/2Ti1/2)O3 (SNT) is synthesized by a solid-state reaction technique. The X-ray diffraction of the sample at room temperature shows a monoclinic phase. The scanning micrograph of the sample shows the average grain size≈0.6μm The field dependence of dielectric response and the loss tangent of the sample are measured in a frequency range from 100Hz to 1MHz and in a temperature range from 313 K to 673 K. An analysis of the real and imaginary parts of the dielectric permittivity with frequency is performed, assuming a distribution of relaxation times as confirmed by Cole-Cole plots. The frequency dependent electrical data are analyzed in the framework of conductivity formalism. The frequency dependent conductivity data are fitted to the universal power law. All these formalisms provided for qualitative similarities in the relaxation times.

  8. Experimental High Resolution (3 km) SMAP Soil Moisture Data Fields With Uncertainty Estimates

    NASA Astrophysics Data System (ADS)

    Das, N. N.

    2015-12-01

    NASA's Soil Moisture Active Passive (SMAP) mission was launched on January 31st, 2015. The objective of the mission is global mapping of surface soil moisture and landscape freeze/thaw state. SMAP utilizes an L-band radar and radiometer sharing a rotating 6-meter mesh reflector antenna. The SMAP spacecraft is in a 685-km Sun-synchronous near-polar orbit, and viewing the surface at a constant 40-degree incidence angle with a 1000-km swath width. Merging of the high-resolution active (radar) and coarse-resolution but high-sensitivity passive (radiometer) L-band observations enable an unprecedented combination of accuracy, resolution, coverage and revisit-time for soil moisture and freeze/thaw state retrievals. However, on July 7th, 2015, the SMAP radar encountered an anomaly and is currently inoperable. Efforts are being made to revive the SMAP radar. Due to the present status of the SMAP observatory, nearly ~2.5 months (from the end of In-Orbit-Check April 13th, 2015 to July 7th, 2015) of the SMAP Active Passive product will be available to public through the NASA DAAC at National Snow and Ice Data Center (NSIDC). The baseline L2_SM_AP product is retrieved soil moisture from the disaggregated/downscaled brightness temperature obtained by merging the coarse-resolution (~36 km) radiometer brightness temperature data and the high-resolution (~3 km) radar backscatter data. The baseline product is intermediate scale 9 km global soil moisture information. Experimentally, a much higher resolution global surface soil moisture data set is also produced at 3 km. This experimental product covering the 2.5 Spring/Summer months is the focus of this presentation. We specifically focus on the analysis of errors and reliability of this data set. The errors in disaggregated brightness temperatures and the retrived soil moisture estimates are discussed. In the presentation the accuracies of the SMAP L2-SM_AP soil moisture retrievals will be shown using summary comparisons with in

  9. Comparison of Two Fluid Replacement Protocols During a 20-km Trail Running Race in the Heat.

    PubMed

    Lopez, Rebecca M; Casa, Douglas J; Jensen, Katherine A; Stearns, Rebecca L; DeMartini, Julie K; Pagnotta, Kelly D; Roti, Melissa W; Armstrong, Lawrence E; Maresh, Carl M

    2016-09-01

    Lopez, RM, Casa, DJ, Jensen, K, Stearns, RL, DeMartini, JK, Pagnotta, KD, Roti, MW, Armstrong, LE, and Maresh, CM. Comparison of two fluid replacement protocols during a 20-km trail running race in the heat. J Strength Cond Res 30(9): 2609-2616, 2016-Proper hydration is imperative for athletes striving for peak performance and safety, however, the effectiveness of various fluid replacement strategies in the field setting is unknown. The purpose of this study was to investigate how two hydration protocols affect physiological responses and performance during a 20-km trail running race. A randomized, counter-balanced, crossover design was used in a field setting (mean ± SD: WBGT 28.3 ± 1.9° C). Well-trained male (n = 8) and female (n = 5) runners (39 ± 14 years; 175 ± 9 cm; 67.5 ± 11.1 kg; 13.4 ± 4.6% BF) completed two 20-km trail races (5 × 4-km loop) with different water hydration protocols: (a) ad libitum (AL) consumption and (b) individualized rehydration (IR). Data were analyzed using repeated measures ANOVA. Paired t-tests compared pre-race-post-race measures. Main outcome variables were race time, heart rate (HR), gastrointestinal temperature (TGI), fluid consumed, percent body mass loss (BML), and urine osmolality (Uosm). Race times between groups were similar. There was a significant condition × time interaction (p = 0.048) for HR, but TGI was similar between conditions. Subjects replaced 30 ± 14% of their water losses in AL and 64 ± 16% of their losses in IR (p < 0.001). Ad libitum trial experienced greater BML (-2.6 ± 0.5%) compared with IR (-1.3 ± 0.5%; p < 0.001). Pre-race to post-race Uosm differences existed between AL (-273 ± 146 mOsm) and IR (-145 ± 215 mOsm, p = 0.032). In IR, runners drank twice as much fluid than AL during the 20-km race, leading to > 2% BML in AL. Ad libitum drinking resulted in 1.3% greater BML over the 20-km race, which resulted in no thermoregulatory or performance differences from IR.

  10. A review of controlled-source electromagnetic science applications and opportunities for imaging in the depth range 20 m to 1 km (Invited)

    NASA Astrophysics Data System (ADS)

    Everett, M. E.

    2009-12-01

    generated by an appropriate source easily penetrate to 1 km. This contribution reviews some of the recent scientific accomplishments in CSEM imaging of the 20 m to 1 km depth range and demonstrates its applicability across a wide range of scientific disciplines.

  11. Extending MGS-TES Temperature Retrievals in the Martian Atmosphere up to 90 Km: Retrieval Approach and Results

    NASA Technical Reports Server (NTRS)

    Feofilov, A. G.; Kutepov, A. A.; Rezac, L.; Smith, M. D.

    2015-01-01

    This paper describes a methodology for performing a temperature retrieval in the Martian atmosphere in the 50-90 km altitude range using spectrally integrated 15 micrometers C02 limb emissions measured by the Thermal Emission Spectrometer (TES), the thermal infrared spectrometer on board the Mars Global Surveyor (MGS). We demonstrate that temperature retrievals from limb observations in the 75-90 km altitude range require accounting for the non-local thermodynamic equilibrium (non-LTE) populations of the C02(v2) vibrational levels. Using the methodology described in the paper, we have retrieved approximately 1200 individual temperature profiles from MGS TES limb observations in the altitude range between 60 and 90 km. 0ur dataset of retrieved temperature profiles is available for download in supplemental materials of this paper. The temperature retrieval uncertainties are mainly caused by radiance noise, and are estimated to be about 2 K at 60 km and below, 4 K at 70 km, 7 K at 80 km, 10 K at 85 km, and 20 K at 90 km. We compare the retrieved profiles to Mars Climate Database temperature profiles and find good qualitative agreement. Quantitatively, our retrieved profiles are in general warmer and demonstrate strong variability with the following values for bias and standard deviations (in brackets) compared to the Martian Year 24 dataset of the Mars Climate Database: 6 (+/-20) K at 60 km, 7.5 (+/-25) K at 65 km, 9 (+/-27) K at 70 km, 9.5 (+/-27) K at 75 km, 10 (+/-28) K at 80 km, 11 (+/-29) K at 85 km, and 11.5 (+/-31) K at 90 km. Possible reasons for the positive temperature bias are discussed. carbon dioxide molecular vibrations

  12. Steady-state kinetics and inhibition of anaerobically purified human homogentisate 1,2-dioxygenase.

    PubMed

    Veldhuizen, Edwin J A; Vaillancourt, Frédéric H; Whiting, Cheryl J; Hsiao, Marvin M-Y; Gingras, Geneviève; Xiao, Yufang; Tanguay, Robert M; Boukouvalas, John; Eltis, Lindsay D

    2005-03-01

    HGO (homogentisate 1,2-dioxygenase; EC 1.13.11.5) catalyses the O2-dependent cleavage of HGA (homogentisate) to maleylacetoacetate in the catabolism of tyrosine. Anaerobic purification of heterologously expressed Fe(II)-containing human HGO yielded an enzyme preparation with a specific activity of 28.3+/- 0.6 micromol x min(-1) x mg(-1) (20 mM Mes, 80 mM NaCl, pH 6.2, 25 degrees C), which is almost twice that of the most active preparation described to date. Moreover, the addition of reducing agents or other additives did not increase the specific activity, in contrast with previous reports. The apparent specificity of HGO for HGA was highest at pH 6.2 and the steady-state cleavage of HGA fit a compulsory-order ternary-complex mechanism (K(m) value of 28.6+/-6.2 microM for HGA, K(m) value of 1240+/-160 microM for O2). Free HGO was subject to inactivation in the presence of O2 and during the steady-state cleavage of HGA. Both cases involved the oxidation of the active site Fe(II). 3-Cl HGA, a potential inhibitor of HGO, and its isosteric analogue, 3-Me HGO, were synthesized. At saturating substrate concentrations, HGO cleaved 3-Me and 3-Cl HGA 10 and 100 times slower than HGA respectively. The apparent specificity of HGO for HGA was approx. two orders of magnitude higher than for either 3-Me or 3-Cl HGA. Interestingly, 3-Cl HGA inactivated HGO only twice as rapidly as HGA. This contrasts with what has been observed in mechanistically related dioxygenases, which are rapidly inactivated by chlorinated substrate analogues, such as 3-hydroxyanthranilate dioxygenase by 4-Cl 3-hydroxyanthranilate.

  13. Steady-state kinetics and inhibition of anaerobically purified human homogentisate 1,2-dioxygenase

    PubMed Central

    2004-01-01

    HGO (homogentisate 1,2-dioxygenase; EC 1.13.11.5) catalyses the O2-dependent cleavage of HGA (homogentisate) to maleylacetoacetate in the catabolism of tyrosine. Anaerobic purification of heterologously expressed Fe(II)-containing human HGO yielded an enzyme preparation with a specific activity of 28.3± 0.6 μmol·min−1·mg−1 (20 mM Mes, 80 mM NaCl, pH 6.2, 25 °C), which is almost twice that of the most active preparation described to date. Moreover, the addition of reducing agents or other additives did not increase the specific activity, in contrast with previous reports. The apparent specificity of HGO for HGA was highest at pH 6.2 and the steady-state cleavage of HGA fit a compulsory-order ternary-complex mechanism (Km value of 28.6±6.2 μM for HGA, Km value of 1240±160 μM for O2). Free HGO was subject to inactivation in the presence of O2 and during the steady-state cleavage of HGA. Both cases involved the oxidation of the active site Fe(II). 3-Cl HGA, a potential inhibitor of HGO, and its isosteric analogue, 3-Me HGO, were synthesized. At saturating substrate concentrations, HGO cleaved 3-Me and 3-Cl HGA 10 and 100 times slower than HGA respectively. The apparent specificity of HGO for HGA was approx. two orders of magnitude higher than for either 3-Me or 3-Cl HGA. Interestingly, 3-Cl HGA inactivated HGO only twice as rapidly as HGA. This contrasts with what has been observed in mechanistically related dioxygenases, which are rapidly inactivated by chlorinated substrate analogues, such as 3-hydroxyanthranilate dioxygenase by 4-Cl 3-hydroxyanthranilate. PMID:15479158

  14. Wide field of view telescope

    DOEpatents

    Ackermann, Mark R.; McGraw, John T.; Zimmer, Peter C.

    2008-01-15

    A wide field of view telescope having two concave and two convex reflective surfaces, each with an aspheric surface contour, has a flat focal plane array. Each of the primary, secondary, tertiary, and quaternary reflective surfaces are rotationally symmetric about the optical axis. The combination of the reflective surfaces results in a wide field of view in the range of approximately 3.8.degree. to approximately 6.5.degree.. The length of the telescope along the optical axis is approximately equal to or less than the diameter of the largest of the reflective surfaces.

  15. Proto-Type Development of Optical Wide-field Patrol Network and Test Observation

    NASA Astrophysics Data System (ADS)

    Park, J.; Choi, Y.; Jo, J.; Moon, H.; Yim, H.; Park, Y.; Hae, Y.; Park, S.; Choi, J.; Son, J.

    2014-09-01

    We present a prototype system developed for optical satellite tracking and its early test observation results. The main objective of the OWL (Optical Wide-field patroL) network is to get orbital information for Korean domestic satellites using optical means only and to maintain their orbital elements. The network is composed of 5 small wide-field telescopes deployed over the world. Each observing station is operated in fully robotic manner from receiving observation schedule to reporting the result, and controlled by the headquarter located in Daejeon, Korea, where orbit calculation and observation strategy will be determined. We developed a compact telescope system for robotic observation and easy maintenance. The telescope is 0.5m of aperture diameter with Rechey-Cretian configuration and its field of view is 1.1 deg. It is equipped with 4K CCD with 9um pixel size, and its pixel scale is 1.2 arcsec/pixel. A chopper wheel with variable speed is adopted to get more points in a single shot. The CCD camera and all the rotating parts (chopper wheel, de-rotator, and filter wheel) are integrated into one compact component called a wheel station. Each observing station is equipped with a fully automatic dome and heavy duty environment monitoring system. We could get an image every 20 seconds and up to ~100 trail points in a single exposure. Each point is time-tagged by ~1/1000 second precision. For one of best cases, we could estimate satellite position with RMS ~ 0.5km accuracy in the along-track with only 4 exposures (~100 points). The first system was installed at the Mongolian site after completing verification test at the testbed site in Daejeon, Korea. The second and third system will be installed in the end of this year.

  16. Preparation of crosslinked 1,2,4-oxadiazole polymer

    NASA Technical Reports Server (NTRS)

    Rosser, R. W.; Shalhoub, I. M.; Kwong, H. (Inventor)

    1981-01-01

    New crosslinked 1,2,4-oxadiazole elastomers were prepared by thermally condensing a monomer having the formula H2N(HON)C-R-Q, wherein Q is a triazine ring-forming group such as nitrile or amidine or a mixture of such group with amidoxime, or a mixture of said monomer with R C(NOH)NH2 sub 2 with R in these formulas standing for a bivalent organic radical. In the monomer charge, the overall proportions of amidoxime groups to triazine ring-forming groups varies depending on the extent of crosslinking desired in the final polymer.

  17. IFSAR reductions from ERS-1,/2 tandem data

    NASA Astrophysics Data System (ADS)

    Poehler, Paul L.; Mansfield, Arthur W.; Rogers, George W.; Rais, Houra

    1998-09-01

    Recent advantages in the areas of phase history processing, interferometric synthetic aperture radar processing algorithms, and the use of photogrammetric techniques have made it possible to extract extremely accurate DEM generation from Synthetic Aperture Radar images. Recent improvements by the authors in the phase unwrapping and interferogram conditioning steps are described which make it possible to obtain good elevation accuracy from noisy interferograms resulting from temporal decorrelation due to foliage or extreme terrain. Results are shown of data reductions from separate passes of the ERS-1,/2 Tandem System over Ft. Irwin, California, and Aschaffenburg, Germany.

  18. Spangolite: an s = 1/2 maple leaf lattice antiferromagnet?

    NASA Astrophysics Data System (ADS)

    Fennell, T.; Piatek, J. O.; Stephenson, R. A.; Nilsen, G. J.; Rønnow, H. M.

    2011-04-01

    Spangolite, Cu6Al(SO4)(OH)12Cl·3H2O, is a hydrated layered copper sulfate mineral. The Cu2 + ions of each layer form a systematically depleted triangular lattice which approximates a maple leaf lattice. We present details of the crystal structure, which suggest that in spangolite this lattice actually comprises two species of edge linked trimers with different exchange parameters. However, magnetic susceptibility measurements show that despite the structural trimers, the magnetic properties are dominated by dimerization. The high temperature magnetic moment is strongly reduced below that expected for the six s = 1/2 in the unit cell.

  19. Role of point defects in bipolar fatigue behavior of Bi(Mg{sub 1/2}Ti{sub 1/2})O{sub 3} modified (Bi{sub 1/2}K{sub 1/2})TiO{sub 3}-(Bi{sub 1/2}Na{sub 1/2})TiO{sub 3} relaxor ceramics

    SciTech Connect

    Kumar, Nitish Ansell, Troy Y.; Cann, David P.

    2014-04-21

    Lead-free Bi(Mg{sub 1/2}Ti{sub 1/2})O{sub 3}-(Bi{sub 1/2}K{sub 1/2})TiO{sub 3}-(Bi{sub 1/2}Na{sub 1/2})TiO{sub 3} (BMT-BKT-BNT) ceramics have been shown to exhibit large electromechanical strains under high electric fields along with negligible fatigue under strong electric fields. To investigate the role of point defects on the fatigue characteristics, the composition 5BMT-40BKT-55BNT was doped to incorporate acceptor and donor defects on the A and B sites by adjusting the Bi/Na and Ti/Mg stoichiometries. All samples had pseudo-cubic symmetries based on x-ray diffraction, typical of relaxors. Dielectric measurements showed that the high and low temperature phase transitions were largely unaffected by doping. Acceptor doping resulted in the observation of a typical ferroelectric-like polarization with a remnant polarization and strain hysteresis loops with significant negative strain. Donor-doped compositions exhibited characteristics that were indicative of an ergodic relaxor phase. Fatigue measurements were carried out on all of the compositions. While the A-site acceptor-doped composition showed a small degradation in maximum strain after 10{sup 6} cycles, the other compositions were essentially fatigue free. Impedance measurements were used to identify the important conduction mechanisms in these compositions. As expected, the presence of defects did not strongly influence the fatigue behavior in donor-doped compositions owing to the nature of their reversible field-induced phase transformation. Even for the acceptor-doped compositions, which had stable domains in the absence of an electric field at room temperature, there was negligible degradation in the maximum strain due to fatigue. This suggests that either the defects introduced through stoichiometric variations do not play a prominent role in fatigue in these systems or it is compensated by factors like decrease in coercive field, an increase in ergodicity, symmetry change, or other factors.

  20. Wide-angle seismic reflection constraints on the lithosphere of the Variscan Belt on SW- Iberia.

    NASA Astrophysics Data System (ADS)

    Palomeras, I.; Ayarza, P.; Afonso, J.; Carbonell, R.; Martinez-Poyatos, D.; Simancas, F.; Gonzalez-Lodeiro, F.; Perez-Estaun, A.

    2008-12-01

    Two wide-angle seismic transects (A and B) were acquired across the Variscan Belt on SW-Iberia. They run across three major tectonic units in the area: South Portuguese Zone, Ossa-Morena Zone, and Central Iberian Zone. Transect A is approximately 300 km long and coincides with the course of the IBERSEIS deep seismic reflection profile. Transect B is 220 km long and is located to the SE of Transect A. The close station spacing along the transects (400 m on Transect A and 150 m on Transect B) allows to identify well defined arrivals within the upper, middle and lower crust as well as in the upper mantle. Resulting velocity models were obtained by forward modeling. The most remarkable features on these models are high velocity areas at mid crustal depths (15-20 km) with velocities in the range of 6.8-7.1 km/s. The Moho discontinuity is located at 31-33 km depth, characterized by a velocity jump from 7.1 km/s to 8.2 km/s. Shot gathers show also a sharp mantle reflection at offsets larger than 180 km which has been modeled as a fairly continuous feature with a velocity increase from 8.2 km/s to 8.4 km/s at 65-67 km depth. The nature of this boundary in still uncertain but it likely reflects a lithological change with subtle velocity/density contrasts, only visible at relatively high incidence angles. The velocity depth function for the crust in the area does not fit any of the standard average crustal velocity models due to the anomalous mid crustal velocities.

  1. One-hundred-km-scale basins on Enceladus: Evidence for an active ice shell

    NASA Astrophysics Data System (ADS)

    Schenk, Paul M.; McKinnon, William B.

    2009-08-01

    Stereo-derived topographic mapping of ˜50% of Enceladus reveals at least 6 large-scale, ovoid depressions (basins) 90-175 km across and 800-to-1500 m deep and uncorrelated with geologic boundaries. In contrast, the south polar depression is larger and apparently shallower and correlates with active resurfacing. The shape and scale of the basins is inconsistent with impact, geoid surface deflections, or with dynamically supported topography. Isostatic thinning of Enceladus' ice shell associated with upwellings (and tidally-driven ice melting) can plausibly account for these basins. Thinning implies upwarping of the base of the shell of ˜10-20 km beneath the depressions, depending on total shell thickness; loss of near-surface porosity due to enhanced heat flow may also contribute to basin lows. Alternatively, the basins may overly cold, inactive, and hence denser ice, but thermal isostasy alone requires thermal expansion more consistent with clathrate hydrate than water ice.

  2. Characterization of the 80-mm diameter Hamamatsu PMTs for the KM3NeT project

    SciTech Connect

    Aiello, S.; Giordano, V.; Leonora, E.; Classen, L.; Reubelt, J.; Peek, H.; Visser, E.; Samtleben, D.; Kalekin, Oleg Collaboration: KM3NeT Collaboration

    2014-11-18

    The optical module designed for the KM3NeT project consists of 31 photomultipliers of 3-inch diameter housed into a 17-inch diameter glass sphere. A proposed photomultiplier was the R12199-02 Hamamatsu 80-mm diameter. 203 of such PMTs have been delivered from Hamamatsu and tested by the KM3NeT groups of NIKHEF-Amsterdam, ECAP-Erlangen and INFN-Catania. Tests have been performed to measure the main parameters, such as gain, transit time spread, dark pulses rate, fraction of spurious pulses, quantum efficiency and effective photocathode size. The main results matched with the requirements of the project. Methods and results are presented in this report.

  3. The Calibration Units of the KM3NeT neutrino telescope

    NASA Astrophysics Data System (ADS)

    Baret, B.; Keller, P.; Clark, M. Lindsey

    2016-04-01

    KM3NeT is a network of deep-sea neutrino telescopes to be deployed in the Mediterranean Sea that will perform neutrino astronomy and oscillation studies. It consists of three-dimensional arrays of thousands of optical modules that detect the Cherenkov light induced by charged particles resulting from the interaction of a neutrino with the surrounding medium. The performance of the neutrino telescope relies on the precise timing and positioning calibration of the detector elements. Other environmental conditions which may affect light and sound transmission, such as water temperature and salinity, must also be continuously monitored. This contribution describes the technical design of the first Calibration Unit, to be deployed on the French site as part of KM3NeT Phase 1.

  4. Measured electric field in the vicinity of a thunderstorm system at an altitude of 37 km

    NASA Technical Reports Server (NTRS)

    Benbrook, J. R.; Kern, J. W.; Sheldon, W. R.

    1974-01-01

    A balloon-borne experiment to measure the atmospheric electric field was flown from the National Scientific Balloon Facility at Palestine, Texas, on July 10, 1973. The electric field and atmospheric conductivity were measured during ascent and for a 4-hour float period at 37-km altitude. Termination of the flight occurred near a thunderstorm line in west Texas. The perturbing influence of the thunderstorms on the electric field was observed at least 100 km from the storm line. The measured electric field is in reasonable agreement with calculations based on simple models of cloud structure and atmospheric conductivity. Large pulses in the measured electric field are interpreted as being the result of intracloud lightning.

  5. Neutral hydrogen flux measured at 100- to 200-km altitude in an electron aurora

    NASA Technical Reports Server (NTRS)

    Iglesias, G. E.; Anderson, H. R.

    1975-01-01

    Neutral hydrogen fluxes were measured at altitudes of 120-200 km by a rocket payload that also measured electron and proton fluxes and vector magnetic fields. An intense electron arc was crossed, while an upper limit to the flux of 0.5- to 20-keV protons was 1,000,000 per sq cm s sr keV. A neutral flux of 50,000,000 per sq cm s sr was observed, assuming hydrogen with greater than 1-keV energy, with greater north-south extent than the electron flux. Its pitch angle distribution was peaked toward 90 deg, tending toward isotropy in the center. This is fitted to a model describing spreading of an initial proton arc above 500 km.

  6. The cytotoxic mechanism of karlotoxin 2 (KmTx 2) from Karlodinium veneficum (Dinophyceae)

    PubMed Central

    Deeds, Jonathan R.; Hoesch, Robert E.; Place, Allen R.; Kao, Joseph P.Y.

    2015-01-01

    This study demonstrates that the polyketide toxin karlotoxin 2 (KmTx 2) produced by Karlodinium veneficum, a dinoflagellate associated with fish kills in temperate estuaries worldwide, alters vertebrate cell membrane permeability. Microfluorimetric and electrophysiological measurements were used to determine that vertebrate cellular toxicity occurs through non-selective permeabilization of plasma membranes, leading to osmotic cell lysis. Previous studies showed that KmTx 2 is lethal to fish at naturally-occurring concentrations measured during fish kills, while sub-lethal doses severely damage gill epithelia. This study provides a mechanistic explanation for the association between K. veneficum blooms and fish kills that has long been observed in temperate estuaries worldwide. PMID:25546005

  7. Identification of pKM101-encoded loci specifying potentially lethal gene products.

    PubMed Central

    Winans, S C; Walker, G C

    1985-01-01

    Two pKM101-encoded loci (designated kilA and kilB) have been identified which elaborate products that are potentially lethal to the bacterial cell. The lethal effects of each of these products is inhibited by two other plasmid-encoded loci, designated korA and korB (for kil override). Both korA and korB are required to control the lethality of either kil gene. In the presence of korA and korB both kil genes have other phenotypes: kilB is necessary for conjugal transfer, whereas kilA is responsible for the small-colony morphology on defined media that is characteristic of pKM101-containing strains (the Slo phenotype). PMID:3881396

  8. KM3NeT Neutrino Telescope 1-ns Resolution Time To Digital Converters

    NASA Astrophysics Data System (ADS)

    Calvo, David; Real, Diego

    2016-04-01

    The KM3NeT collaboration aims the construction of a multi-km3 high-energy neutrino telescope in the Mediterranean sea consisting of thousands of glass spheres, each of them containing 31 photomultiplier of small photocathode area. The main digitization system is composed by 31 Time to Digital Converter channels with 1-ns resolution embedded in a Field Programmable Gate Array. An architecture with low resource occupancy has been chosen allowing the implementation of other instrumentation, communication and synchronization systems on the same device. The 4-oversampling technique with two high frequency clocks working in opposed phases has been used together with an asymmetric FIFO memory. In the present article the architecture and the first results obtained with the Time to Digital Converters are presented.

  9. Progress toward a Km-scale neutrino detector in the deep ocean

    SciTech Connect

    Stokstad, R.G.

    1997-11-01

    The best particles for observing distant objects are photons and neutrinos. Because of the neutrino`s weak interaction cross section, detectors suitable for astronomy must be very large and well shielded from cosmic rays. Eventually, a detector with the order of a square km of effective area will be needed for systematic observations of distant point sources such as active galactic nuclei. Prototype detectors are currently being developed at several sites in the ocean, at Lake Baikal, and in Antarctica. This talk summarizes the status of the projects that use the deep ocean for the detector medium and shielding: DUMAND, NESTOR and ANTARES. Technical developments will be needed for a future km-scale detector; progress on one of these, a digital electronic system, is also described.

  10. ERTS surveys a 500 km squared locust breeding site in Saudi Arabia. [Red Sea coastal plain

    NASA Technical Reports Server (NTRS)

    Pedgley, D. E.

    1974-01-01

    From September 1972 to January 1973, ERTS-1 precisely located a 500 sq km area on the Red Sea coastal plain of Saudi Arabia within which the Desert Locust (Schistocerca gregaria, Forsk.) bred successfully and produced many small swarms. Growth of vegetation shown by satellite imagery was confirmed from ground surveys and raingauge data. The experiment demonstrates the feasibility of detecting potential locust breeding sites by satellite, and shows that an operational satellite would be a powerful tool for routine survey of the 3 x 10 to the 7th power sq km invasion area of the Desert Locust in Africa and Asia, as well as of other locust species in the arid and semi-arid tropics.

  11. First results of the KM3NeT multi-PMT DOM

    SciTech Connect

    Michael, Tino; Collaboration: KM3NeT Collaboration

    2014-11-18

    The future KM3NeT neutrino telescope will consist of several thousand digital optical modules (DOMs), each of which will be equipped with 31 3-inch photo-multiplier tubes (PMTs). This design has various advantages over the use of one large PMT per optical module, e.g. concerning effective photocathode area per module, improved background suppression and directional reconstruction. Currently, the KM3NeT collaboration is testing a prototype DOM deployed on the instrumentation line of the ANTARES neutrino telescope. The DOM has been operational since mid-April 2013. First data are presented and compared to simulation results. The results are very encouraging and indicate that muon identification and a coarse direction estimation are possible event with a single DOM.

  12. Evaluation of Whipple Bumper shields at 7 and 10 km/s

    NASA Technical Reports Server (NTRS)

    Ang, J. A.; Chhabildas, L. C.; Cour-Palais, B. G.; Christiansen, E. L.; Crews, J. L.

    1992-01-01

    A series of experiments has been performed on the Sandia Hypervelocity Launcher to determine the performance limits of conventional Whipple shields against representative 0.8 g aluminum orbital debris plate-like fragments with velocities of 7 and 10 km/s. Supporting diagnostics include flash X-rays, high speed photography and transient digitizers for timing correlation. Two Whipple shield designs were tested with either a 0.030 cm or a 0.127 cm thick front sheet and a 0.407 cm thick backsheet separated by 30.5 cm. These two designs bracket the ballistic penetration limit curve for protection against these debris simulants for 7 km/s impacts.

  13. Isotope shifts of the 2 p3 /2-2 p1 /2 transition in B-like ions

    NASA Astrophysics Data System (ADS)

    Zubova, N. A.; Malyshev, A. V.; Tupitsyn, I. I.; Shabaev, V. M.; Kozhedub, Y. S.; Plunien, G.; Brandau, C.; Stöhlker, Th.

    2016-05-01

    Isotope shifts of the 2 p3 /2-2 p1 /2 transition in B-like ions are evaluated for a wide range of the nuclear charge number: Z =8 -92 . The calculations of the relativistic nuclear recoil and nuclear size effects are performed using a large-scale configuration-interaction Dirac-Fock-Sturm method. The corresponding QED corrections are also taken into account. The results of the calculations are compared with the theoretical values obtained with other methods. The accuracy of the isotope shifts of the 2 p3 /2-2 p1 /2 transition in B-like ions is significantly improved.

  14. The modelled surface mass balance of the Antarctic Peninsula at 5.5 km horizontal resolution

    NASA Astrophysics Data System (ADS)

    van Wessem, J. M.; Ligtenberg, S. R. M.; Reijmer, C. H.; van de Berg, W. J.; van den Broeke, M. R.; Barrand, N. E.; Thomas, E. R.; Turner, J.; Wuite, J.; Scambos, T. A.; van Meijgaard, E.

    2016-02-01

    This study presents a high-resolution (˜ 5.5 km) estimate of surface mass balance (SMB) over the period 1979-2014 for the Antarctic Peninsula (AP), generated by the regional atmospheric climate model RACMO2.3 and a firn densification model (FDM). RACMO2.3 is used to force the FDM, which calculates processes in the snowpack, such as meltwater percolation, refreezing and runoff. We evaluate model output with 132 in situ SMB observations and discharge rates from six glacier drainage basins, and find that the model realistically simulates the strong spatial variability in precipitation, but that significant biases remain as a result of the highly complex topography of the AP. It is also clear that the observations significantly underrepresent the high-accumulation regimes, complicating a full model evaluation. The SMB map reveals large accumulation gradients, with precipitation values above 3000 mm we yr-1 in the western AP (WAP) and below 500 mm we yr-1 in the eastern AP (EAP), not resolved by coarser data sets such as ERA-Interim. The average AP ice-sheet-integrated SMB, including ice shelves (an area of 4.1 × 105 km2), is estimated at 351 Gt yr-1 with an interannual variability of 58 Gt yr-1, which is dominated by precipitation (PR) (365 ± 57 Gt yr-1). The WAP (2.4 × 105 km2) SMB (276 ± 47 Gt yr-1), where PR is large (276 ± 47 Gt yr-1), dominates over the EAP (1.7 × 105 km2) SMB (75 ± 11 Gt yr-1) and PR (84 ± 11 Gt yr-1). Total sublimation is 11 ± 2 Gt yr-1 and meltwater runoff into the ocean is 4 ± 4 Gt yr-1. There are no significant trends in any of the modelled AP SMB components, except for snowmelt that shows a significant decrease over the last 36 years (-0.36 Gt yr-2).

  15. The prototype detection unit of the KM3NeT detector

    NASA Astrophysics Data System (ADS)

    Adrián-Martínez, S.; Ageron, M.; Aharonian, F.; Aiello, S.; Albert, A.; Ameli, F.; Anassontzis, E. G.; Androulakis, G. C.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardid, M.; Avgitas, T.; Balasi, K.; Band, H.; Barbarino, G.; Barbarito, E.; Barbato, F.; Baret, B.; Baron, S.; Barrios, J.; Belias, A.; Berbee, E.; van den Berg, A. M.; Berkien, A.; Bertin, V.; Beurthey, S.; van Beveren, V.; Beverini, N.; Biagi, S.; Biagioni, A.; Bianucci, S.; Billault, M.; Birbas, A.; Boer Rookhuizen, H.; Bormuth, R.; Bouché, V.; Bouhadef, B.; Bourlis, G.; Boutonnet, C.; Bouwhuis, M.; Bozza, C.; Bruijn, R.; Brunner, J.; Cacopardo, G.; Caillat, L.; Calamai, M.; Calvo, D.; Capone, A.; Caramete, L.; Caruso, F.; Cecchini, S.; Ceres, A.; Cereseto, R.; Champion, C.; Château, F.; Chiarusi, T.; Christopoulou, B.; Circella, M.; Classen, L.; Cocimano, R.; Coleiro, A.; Colonges, S.; Coniglione, R.; Cosquer, A.; Costa, M.; Coyle, P.; Creusot, A.; Cuttone, G.; D'Amato, C.; D'Amico, A.; De Bonis, G.; De Rosa, G.; Deniskina, N.; Destelle, J.-J.; Distefano, C.; Di Capua, F.; Donzaud, C.; Dornic, D.; Dorosti-Hasankiadeh, Q.; Drakopoulou, E.; Drouhin, D.; Drury, L.; Durand, D.; Eberl, T.; Elsaesser, D.; Enzenhöfer, A.; Fermani, P.; Fusco, L. A.; Gajanana, D.; Gal, T.; Galatà, S.; Garufi, F.; Gebyehu, M.; Giordano, V.; Gizani, N.; Gracia Ruiz, R.; Graf, K.; Grasso, R.; Grella, G.; Grmek, A.; Habel, R.; van Haren, H.; Heid, T.; Heijboer, A.; Heine, E.; Henry, S.; Hernández-Rey, J. J.; Herold, B.; Hevinga, M. A.; van der Hoek, M.; Hofestädt, J.; Hogenbirk, J.; Hugon, C.; Hößl, J.; Imbesi, M.; James, C. W.; Jansweijer, P.; Jochum, J.; de Jong, M.; Jongen, M.; Kadler, M.; Kalekin, O.; Kappes, A.; Kappos, E.; Katz, U.; Kavatsyuk, O.; Keller, P.; Kieft, G.; Koffeman, E.; Kok, H.; Kooijman, P.; Koopstra, J.; Korporaal, A.; Kouchner, A.; Kreykenbohm, I.; Kulikovskiy, V.; Lahmann, R.; Lamare, P.; Larosa, G.; Lattuada, D.; Le Provost, H.; Leismüller, K. P.; Leisos, A.; Lenis, D.; Leonora, E.; Lindsey Clark, M.; Llorens Alvarez, C. D.; Löhner, H.; Lonardo, A.; Loucatos, S.; Louis, F.; Maccioni, E.; Mannheim, K.; Manolopoulos, K.; Margiotta, A.; Mariş, O.; Markou, C.; Martínez-Mora, J. A.; Martini, A.; Masullo, R.; Melis, K. W.; Michael, T.; Migliozzi, P.; Migneco, E.; Miraglia, A.; Mollo, C. M.; Mongelli, M.; Morganti, M.; Mos, S.; Moudden, Y.; Musico, P.; Musumeci, M.; Nicolaou, C.; Nicolau, C. A.; Orlando, A.; Orzelli, A.; Papaikonomou, A.; Papaleo, R.; Păvălaş, G. E.; Peek, H.; Pellegrino, C.; Pellegriti, M. G.; Perrina, C.; Piattelli, P.; Pikounis, K.; Popa, V.; Pradier, Th.; Priede, M.; Pühlhofer, G.; Pulvirenti, S.; Racca, C.; Raffaelli, F.; Randazzo, N.; Rapidis, P. A.; Razis, P.; Real, D.; Resvanis, L.; Reubelt, J.; Riccobene, G.; Rovelli, A.; Saldaña, M.; Samtleben, D. F. E.; Sanguineti, M.; Santangelo, A.; Sapienza, P.; Schmelling, J.; Schnabel, J.; Sciacca, V.; Sedita, M.; Seitz, T.; Sgura, I.; Simeone, F.; Sipala, V.; Spitaleri, A.; Spurio, M.; Stavropoulos, G.; Steijger, J.; Stolarczyk, T.; Stransky, D.; Taiuti, M.; Terreni, G.; Tézier, D.; Théraube, S.; Thompson, L. F.; Timmer, P.; Trasatti, L.; Trovato, A.; Tselengidou, M.; Tsirigotis, A.; Tzamarias, S.; Tzamariudaki, E.; Vallage, B.; Van Elewyck, V.; Vermeulen, J.; Vernin, P.; Vicini, P.; Viola, S.; Vivolo, D.; Werneke, P.; Wiggers, L.; Wilms, J.; de Wolf, E.; van Wooning, R. H. L.; Zonca, E.; Zornoza, J. D.; Zúñiga, J.; Zwart, A.

    2016-02-01

    A prototype detection unit of the KM3NeT deep-sea neutrino telescope has been installed at 3500m depth 80 km offshore the Italian coast. KM3NeT in its final configuration will contain several hundreds of detection units. Each detection unit is a mechanical structure anchored to the sea floor, held vertical by a submerged buoy and supporting optical modules for the detection of Cherenkov light emitted by charged secondary particles emerging from neutrino interactions. This prototype string implements three optical modules with 31 photomultiplier tubes each. These optical modules were developed by the KM3NeT Collaboration to enhance the detection capability of neutrino interactions. The prototype detection unit was operated since its deployment in May 2014 until its decommissioning in July 2015. Reconstruction of the particle trajectories from the data requires a nanosecond accuracy in the time calibration. A procedure for relative time calibration of the photomultiplier tubes contained in each optical module is described. This procedure is based on the measured coincidences produced in the sea by the ^{40}K background light and can easily be expanded to a detector with several thousands of optical modules. The time offsets between the different optical modules are obtained using LED nanobeacons mounted inside them. A set of data corresponding to 600 h of livetime was analysed. The results show good agreement with Monte Carlo simulations of the expected optical background and the signal from atmospheric muons. An almost background-free sample of muons was selected by filtering the time correlated signals on all the three optical modules. The zenith angle of the selected muons was reconstructed with a precision of about 3°.

  16. Compositional mantle layering revealed by slab stagnation at ~1,000 km depth

    NASA Astrophysics Data System (ADS)

    Ballmer, M. D.; Nakagawa, T.; Schmerr, N. C.; Ritsema, J.; Motoki, M.

    2015-12-01

    Improved constraints on lower-mantle composition are fundamental to understand the accretion, differentiation and thermochemical evolution of our planet. Whereas cosmochemical arguments indicate that lower-mantle rocks may be enriched in Si relative to upper-mantle pyrolite, seismic tomography images suggest whole-mantle convection and efficient mantle mixing. This study reconciles cosmochemical and geophysical constraints using the stagnation of some slab segments at ~1,000 km depth as the key observation. Whereas slab stagnation at ~660 km depth is well explained by the effects of the spinel-perovskite endothermic phase transition, flattening of slabs in the uppermost lower mantle remains poorly understood. Through numerical modeling of subduction, we show that enrichment of the lower mantle in intrinsically dense basaltic heterogeneity can render slabs neutrally buoyant at ~1,000 km depth. Slab stagnation (at ~660 and ~1,000 km depth) as well as unimpeded slab sinking to great depths can only coexist as three different modes of slab sinking behavior on Earth if the basalt fraction is ~8% higher in the lower than in the upper mantle, equivalent to a lower-mantle Mg/Si of ~1.18. Geodynamic models demonstrate that such a moderate compositional gradient can be sustained by compositional filtering of both slabs and plumes as they cross the transition zone, and thus persist over billions of years of whole-mantle convection. Whereas basaltic heterogeneity tends to get trapped in the transition zone and ultimately sink into the lower mantle, harzburgitic heterogeneity tends to rise into the uppermost mantle.

  17. Seismic evidence of negligible water carried below 400-km depth in subducting lithosphere.

    PubMed

    Green, Harry W; Chen, Wang-Ping; Brudzinski, Michael R

    2010-10-14

    Strong evidence exists that water is carried from the surface into the upper mantle by hydrous minerals in the uppermost 10-12 km of subducting lithosphere, and more water may be added as the lithosphere bends and goes downwards. Significant amounts of that water are released as the lithosphere heats up, triggering earthquakes and fluxing arc volcanism. In addition, there is experimental evidence for high solubility of water in olivine, the most abundant mineral in the upper mantle, for even higher solubility in olivine's high-pressure polymorphs, wadsleyite and ringwoodite, and for the existence of dense hydrous magnesium silicates that potentially could carry water well into the lower mantle (deeper than 1,000 km). Here we compare experimental and seismic evidence to test whether patterns of seismicity and the stabilities of these potentially relevant hydrous phases are consistent with a wet lithosphere. We show that there is nearly a one-to-one correlation between dehydration of minerals and seismicity at depths less than about 250 km, and conclude that the dehydration of minerals is the trigger of instability that leads to seismicity. At greater depths, however, we find no correlation between occurrences of earthquakes and depths where breakdown of hydrous phases is expected. Lastly, we note that there is compelling evidence for the existence of metastable olivine (which, if present, can explain the distribution of deep-focus earthquakes) west of and within the subducting Tonga slab and also in three other subduction zones, despite metastable olivine being incompatible with even extremely small amounts of water (of the order of 100 p.p.m. by weight). We conclude that subducting slabs are essentially dry at depths below 400 km and thus do not provide a pathway for significant amounts of water to enter the mantle transition zone or the lower mantle.

  18. Correlation of the 410 km Discontinuity Low Velocity Layer with Tomographic Wavespeed Variations

    NASA Astrophysics Data System (ADS)

    Zhang, Z.; Dueker, K. G.

    2010-12-01

    The transition zone water-filter model predicts that a hydrous melt layer at the 410-km discontinuity is only actively produced in upwelling region, and does not exist in downwelling region (Bercovici and Karato, 2003). This prediction has been tested by stacking of P-S receiver functions using the RISTRA linear array which crosses west-Texas, New Mexico and Utah. The receiver functions are binned into the NW, SE, SW azimuthal quadrants and stacked to produce well-resolved images of the 410- and 660-km discontinuities. The three receiver function quadrant stack images find a correlation between the occurrence of negative polarity 410-km low velocity layer arrival and the teleseismic body wave velocity tomogram of Schmandt and Humphreys (2010); the 410 low velocity layer arrival is absent where the velocities about the 410 km discontinuity are relatively high and present where the velocities are low. Our finding is consistent with a simple interpretation of the transition zone water filter model which predicts the production of a hydrous melt layer where upflow of sufficiently hydrated transition zone mantle occurs and destruction of a hydrous melt layer where there is downflow. We test this prediction by analyzing the Colorado Rockies Experiment and Seismic Transects (CREST) seismic data which was collected in 2008-2009. This 15 month deployment of 59 CREST stations in tandem with 31 Transportable Array stations yields a total of 161 Mb>5.5 events at 30°-95° distances. The P-S receiver functions are calculated using a multi-channel deconvolution methodology and filtered with a 30-3 s post-deconvolution filter. The receiver function dataset contains about 1800 SV components after RMS, cross-correlation, and visual data quality culling. Common conversion point images are constructed using Pds timing correction from a 3-D upper mantle tomography model (McCarthy and Aster, pers. com.) to account for lateral P/S velocity heterogeneity.

  19. Performance during a 20-km cycling time-trial after caffeine ingestion

    PubMed Central

    2014-01-01

    Background The objective of this study was to analyze the effect of caffeine ingestion on the performance and physiological variables associated with fatigue in 20-km cycling time trials. Methods In a double-blind placebo-controlled crossover study, 13 male cyclists (26 ± 10 y, 71 ± 9 kg, 176 ± 6 cm) were randomized into 2 groups and received caffeine (CAF) capsules (6 mg.kg−1) or placebo (PLA) 60 min before performing 20-km time trials. Distance, speed, power, rpm, rating of perceived exertion (RPE), electromyography (EMG) of the quadriceps muscles and heart rate (HR) were continuously measured during the tests. In addition, BRUMS questionnaire was applied before and after the tests. Results Significant interactions were found in power and speed (P = 0.001), which were significantly higher at the end of the test (final 2 km) after CAF condition. A main effect of time (P = 0.001) was observed for RPE and HR, which increased linearly until the end of exercise in both conditions. The time taken to complete the test was similar in both conditions (PLA = 2191 ± 158 s vs. CAF = 2181 ± 194 s, P = 0.61). No significant differences between CAF and PLA conditions were identified for speed, power, rpm, RPE, EMG, HR, and BRUMS (P > 0.05). Conclusion The results suggest that caffeine intake 60 min before 20-km time trials has no effect on the performance or physiological responses of cyclists. PMID:25302056

  20. Silicon ions below 100 km - A case for SiO2/+/. [during meteoroid shower

    NASA Technical Reports Server (NTRS)

    Goldberg, R. A.

    1975-01-01

    An investigation regarding the occurrence of Si ions is conducted, taking into account an unusual metal ion structure observed during a meteor shower event. Loss processes involving silicon oxides are considered in connection with a study of the reasons for the unique Si(+) distribution found. It is suggested that below 100 km Si(+) is rapidly depleted by two- and three-body reactions with molecular oxygen, forming SiO2(+) which then recombines.