Science.gov

Sample records for 1-4 mile resolution

  1. Validity and reliability of the 1/4 mile run-walk test in physically active children and adolescents.

    PubMed

    Ruiz, Jonatan R; Ortega, Francisco B; Castro-Piñero, Jose

    2014-11-30

    We investigated the criterion-related validity and the reliability of the 1/4 mile run-walk test (MRWT) in children and adolescents. A total of 86 children (n=42 girls) completed a maximal graded treadmill test using a gas analyzer and the 1/4MRW test. We investigated the test-retest reliability of the 1/4MRWT in a different group of children and adolescents (n=995, n=418 girls). The 1/4MRWT time, sex, and BMI significantly contributed to predict measured VO2peak (R2= 0.32). There was no systematic bias in the cross-validation group (P>0.1). The root mean sum of squared errors (RMSE) and the percentage error were 6.9 ml/kg/min and 17.7%, respectively, and the accurate prediction (i.e. the percentage of estimations within ±4.5 ml/kg/min of VO2peak) was 48.8%. The reliability analysis showed that the mean inter-trial difference ranged from 0.6 seconds in children aged 6-11 years to 1.3 seconds in adolescents aged 12-17 years (all P.

  2. Structure of the Drosophila melanogaster Rab6 GTPase at 1.4 Å resolution

    PubMed Central

    Walden, Miriam; Jenkins, Huw T.; Edwards, Thomas A.

    2011-01-01

    Rab6 is a small GTPase that belongs to the p21 Ras superfamily. It is involved in vesicle trafficking between the Golgi apparatus and endosomes/ER in eukaryotes. The GDP-bound inactive protein undergoes conformational changes when the nucleotide is exchanged to GTP, allowing Rab6 to interact with a variety of different effector proteins. To further understand how these changes affect downstream protein binding, the crystal structure of Rab6 from Drosophila melanogaster has been solved to 1.4 Å resolution, the highest resolution for a Rab6 structure to date. The crystals belonged to space group C2, with unit-cell parameters a = 116.5, b = 42.71, c = 86.86 Å, α = 90, β = 133.12, γ = 90°. The model was refined to an R factor of 14.5% and an R free of 17.3%. PMID:21795785

  3. Analysis of the rotational structure in the high-resolution infrared spectra of cis,cis- and trans,trans-1,4-difluorobutadiene-1-d1 and trans,trans-1,4-difluorobutadiene-1,4-d2

    SciTech Connect

    Craig, Norman C.; Chen, Yihui; Lu, Yuhua; Neese, Christopher F.; Nemchick, Deacon J.; Blake, Thomas A.

    2013-06-01

    Samples of cis,cis- and trans,trans-1,4-difluorobutadiene-1- d1 and of trans,trans-1,4-difluorobutadiene-1,4-d2 have been synthesized, and high-resolution (≤0.0018 cm-1) infrared spectra of these substances have been recorded in the gas phase. Analysis of the rotational structure, mostly in C-type bands, has yielded ground state rotational constants. For the two 1-d1 species more than one band has been analyzed. For the 1,4-d2 species only one band was available for analysis. However, good agreement between the experimental centrifugal distortion constants and those predicted with a B3LYP/cc-pVTZ model give strong support to the analysis of the very dense spectrum. The ground state rotational constants are a contribution to finding semiexperimental equilibrium structures of the two nonpolar isomers of 1,4- difluorobutadiene.

  4. New high resolution VLA mosaic at 1.4 GHz of the SNR Puppis A

    NASA Astrophysics Data System (ADS)

    Castelletti, G.; Dubner, G. M.; Golap, K.; Goss, W. M.

    2006-06-01

    We present new observations at 1.4 GHz of the supernova remnant (SNR) Puppis A made with the VLA in the hybrid DnC and CnB configurations (in 2003 and 2004, respectively). We observed this extended remnant (about 55' diameter) applying a mosaicking technique to combine 39 different pointings. The data were reduced using the AIPS++ software package. The multiscale clean method was used to deconvolve the image. The interferometric image was combined with single dish data extracted from the Parkes Southern Galactic Plane Survey (McClure-Griffiths et al. 2001, AJ, 551, 394) following a feathering technique which involves Fourier transforming of both the single dish and interferometric data onto identical grids. The new image produced by uniformly weighted visibility data, has a final angular resolution of 34 arcsec × 16 arcsec and an rms noise level of 0.5 mJy beam^{-1}; the improvement represents a factor of two in angular resolution and almost ten times in sensitivity compared to the best previous image of Puppis A at 1515 MHz (Dubner et al. 1991, AJ, 101, 1466; HPBW 77 arcsec × 43arcsec, rms noise 3 mJy beam^{-1}). For the first time a highly structured border encircling a diffuse, almost featureless interior was revealed in Puppis A. In particular the northern half of Puppis A displays a wealth of structure along the periphery consisting of short arcs that appear to be oriented rather perpendicular to the shock front on the northeast quadrant, but tangential to it on the northweast side.

  5. Analysis of the Rotational Structure in the High-Resolution Infrared Spectra of cis,cis- and trans,trans-1,4-DIFLUOROBUTADIENE-1-d_{1} and trans,trans-1,4-DIFLUOROBUTADIENE-1,4-d_{2}

    NASA Astrophysics Data System (ADS)

    Craig, Norman C.; Chen, Yihui; Lu, Yuhua; Neese, Christopher F.; Nemchick, Deacon J.; Blake, Thomas A.

    2013-06-01

    Samples of cis,cis- and trans,trans-1,4-difluorobutadiene-1-d_{1} (DFBD) and trans,trans-DFBD-1,4-d_{2} have been synthesized and investigated with high-resolution (0.0015 cm^{-1}) infrared spectroscopy. For the first two species the rotational structure in more than one band has been analyzed. For the 1,4-d_{2} species the spectrum of only one C-type band was available in an isotopic mixture. Ground state rotational constants are reported for all three molecules. It is proposed that quartic centrifugal distortion constants computed with a B3LYP/cc-pVTZ model can be used to assess the quality of observed rotational constants. The favorable comparison of predicted and observed ground state rotational constants for all four ^{13}C species of cis,trans-DFBD, which is MW active, demonstrates that the ground state rotational constants for the ^{13}C species of the cis,cis and trans,trans isomers can be successfully predicted with high accuracy. Rotational constants for a full set of isotopologues will be used to determine accurate semiexperimental equilibrium structures of the cis,cis and trans,trans species of DFBD. N. C. Craig, C. M. Oertel, D. C. Oertel, M. J. Tubergen, R. J. Lavrich, A. M Chaka J. Phys. Chem. A 106, 4230-4235 (2002).

  6. Ab initio protein phasing at 1.4 A resolution: the new phasing approach of SIR2003-N.

    PubMed

    Burla, Maria C; Carrozzini, Benedetta; Caliandro, Rocco; Cascarano, Giovanni L; De Caro, Liberato; Giacovazzo, Carmelo; Polidori, Giampiero

    2003-11-01

    New algorithms for solving ab initio protein crystal structures have been identified and implemented in a modified version of the program SIR2002. They succeed in solving numerous protein structures diffracting at atomic resolution; the solution was also attained when data were cut at 1.4 A resolution. The direct-space refinement procedure of SIR2003-N takes advantage of using the envelope of the protein, calculated during the phasing process from the current phases. The electron-density map is modified by assuming different weights for pixels within the envelope or out of it, so tentatively depleting the intensities of the false peaks. The map is then inverted and the resulting phase sets may improve their values. The new phasing strategy is also based on an optimal use of some figures of merit, one of which may be successfully applied in the early stages of the phasing process: only the most promising trials are submitted to the complete phasing procedure, so saving computing time. SIR2003-N has been successfully applied also in solving some protein structures diffracting at 1.4-1.5 A resolution.

  7. HIGH-RESOLUTION VERY LARGE ARRAY IMAGING OF SLOAN DIGITAL SKY SURVEY STRIPE 82 AT 1.4 GHz

    SciTech Connect

    Hodge, J. A.; Becker, R. H.; Zeimann, G. R.; White, R. L.; Richards, G. T.

    2011-07-15

    We present a high-resolution radio survey of the Sloan Digital Sky Survey (SDSS) Southern Equatorial Stripe, a.k.a. Stripe 82. This 1.4 GHz survey was conducted with the Very Large Array primarily in the A-configuration, with supplemental B-configuration data to increase sensitivity to extended structure. The survey has an angular resolution of 1.''8 and achieves a median rms noise of 52 {mu}Jy beam{sup -1} over 92 deg{sup 2}. This is the deepest 1.4 GHz survey to achieve this large of an area, filling a gap in the phase space between small, deep and large, shallow surveys. It also serves as a pilot project for a larger high-resolution survey with the Expanded Very Large Array. We discuss the technical design of the survey and details of the observations, and we outline our method for data reduction. We present a catalog of 17,969 isolated radio components, for an overall source density of {approx}195 sources deg{sup -2}. The astrometric accuracy of the data is excellent, with an internal check utilizing multiply observed sources yielding an rms scatter of 0.''19 in both right ascension and declination. A comparison to the SDSS DR7 Quasar Catalog further confirms that the astrometry is well tied to the optical reference frame, with mean offsets of 0.''02 {+-} 0.''01 in right ascension, and 0.''01 {+-} 0.''02 in declination. A check of our photometry reveals a small, negative CLEAN-like bias on the level of 35 {mu}Jy. We report on the catalog completeness, finding that 97% of FIRST-detected quasars are recovered in the new Stripe 82 radio catalog, while faint, extended sources are more likely to be resolved out by the resolution bias. We conclude with a discussion of the optical counterparts to the catalog sources, including 76 newly detected radio quasars. The full catalog as well as a search page and cutout server are available online at http://third.ucllnl.org/cgi-bin/stripe82cutout.

  8. High-resolution infrared spectroscopy of HCN-Znn (n = 1-4) clusters: structure determination and comparisons with theory.

    PubMed

    Stiles, Paul L; Miller, Roger E

    2006-05-04

    High-resolution infrared laser spectroscopy has been used to obtain rotationally resolved spectra of HCN-Zn(n) (n = 1-4) complexes formed in helium nanodroplets. In the present study the droplets passed through a metal oven, where the zinc vapor pressure was adjusted until one or more atoms were captured by the droplets. A second pickup cell was then used to dope the droplets with a single HCN molecule. Rotationally resolved infrared spectra are obtained for all of these complexes, providing valuable information concerning their structures. Stark spectra are reported and used to determine the corresponding permanent electric dipole moments. Ab initio calculations are also reported for these complexes for comparison with the experimental results.

  9. Crystal structure of intercalated four-stranded d(C3T) at 1.4 angstroms resolution

    NASA Technical Reports Server (NTRS)

    Kang, C. H.; Berger, I.; Lockshin, C.; Ratliff, R.; Moyzis, R.; Rich, A.

    1994-01-01

    The crystal structure of d(C3T), solved at 1.4 angstroms resolution, reveals that the molecule forms a four-stranded intercalated complex. It consists of two parallel-stranded duplexes, each of which is held together by cytosine-protonated cytosine base pairs. The two duplexes are intercalated with each other and have opposite strand orientation. The molecule has a flat, lath-like appearance, and the covalently bonded cytosines have a slow right-handed twist of 17.1 degrees. However, there is considerable asymmetry. On one of the flat sides, the phosphate groups are rotated away from the center of the molecule. They are held in this orientation by bridging water molecules that bind the NH of cytosine and a phosphate group of an opposite chain. There is also considerable microheterogeneity in the structure. The cytosine hemiprotonation occurs even at pH 7 where stable crystals form.

  10. Three-dimensional structure of homodimeric cholesterol esterase-ligand complex at 1.4 Å resolution

    SciTech Connect

    Pletnev, V.; Addlagatta, A.; Wawrzak, Z.; Duax, W.

    2010-03-08

    The three-dimensional structure of a Candida cylindracea cholesterol esterase (ChE) homodimer (534 x 2 amino acids) in complex with a ligand of proposed formula C{sub 23}H{sub 48}O{sub 2} has been determined at 1.4 {angstrom} resolution in space group P1 using synchrotron low-temperature data. The structure refined to R = 0.136 and R{sub free} = 0.169 and has revealed new stereochemical details in addition to those detected for the apo- and holo-forms at 1.9 and 2.0 {angstrom} resolution, respectively [Ghosh et al. (1995), Structure, 3, 279-288]. The cholesterol esterase structure is a dimer with four spatially separated interfacial contact areas and two symmetry-related pairs of openings to an internal intradimer cavity. Hydrophobic active-site gorges in each subunit face each other across a central interfacial cavity. The ChE subunits have carbohydrate chains attached to their Asn314 and Asn351 residues, with two ordered N-acetyl-D-glucosoamine moieties visible at each site. The side chains of 14 residues have two alternative conformations with occupancy values of 0.5 {+-} 0.2. For each subunit the electron density in the enzyme active-site gorge is well modeled by a C{sub 23}-chain fatty acid.

  11. High-performance liquid chromatographic resolution of 1-(1,4-benzodioxane-2-formyl)-piperazine enantiomers after chiral derivatization.

    PubMed

    Chen, Zhiqiong; Yu, Yu; Li, Longjiang

    2005-02-01

    Chiral separation of racemic mixtures is of the greatest importance to the pharmaceutical industry, as the isomers of a given racemate may exhibit substantially different pharmacological effects, not to mention possibly differing toxicity behaviour. A novel chiral separation method is developed for the determination of 1-(1,4-benzodioxane-2-formyl)piperazine (BFP) enantiomers. The indirect resolution is performed by applying precolumn derivatization with the chiral reagent 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate (GITC). The resulting diastereoisomers are separated on a reversed-phase ODS column with methanol-potassium dihydrogen phosphate (0.02mol/L, 50:50) as mobile phase. UV detection is at 250 nm. The effect of mobile phase composition upon resolution and analysis time is investigated. Two diastereoisomers show nearly base-line separation under optimal chromatographic conditions. The presented study provides a simple and accurate method for the enantiomeric quality control and the optical purity assay of BFP.

  12. Common and distinctive features of GNRA tetraloops based on a GUAA tetraloop structure at 1.4 Å resolution

    PubMed Central

    CORRELL, CARL C.; SWINGER, KERREN

    2003-01-01

    GNRA tetraloops (N is A, C, G, or U; R is A or G) are basic building blocks of RNA structure that often interact with proteins or other RNA structural elements. Understanding sequence-dependent structural variation among different GNRA tetraloops is an important step toward elucidating the molecular basis of specific GNRA tetraloop recognition by proteins and RNAs. Details of the geometry and hydration of this motif have been based on high-resolution crystallographic structures of the GRRA subset of tetraloops; less is known about the GYRA subset (Y is C or U). We report here the structure of a GUAA tetraloop determined to 1.4 Å resolution to better define these details and any distinctive features of GYRA tetraloops. The tetraloop is part of a 27-nt structure that mimics the universal sarcin/ricin loop from Escherichia coli 23S ribosomal RNA in which a GUAA tetraloop replaces the conserved GAGA tetraloop. The adenosines of the GUAA tetraloop form an intermolecular contact that is a commonplace RNA tertiary interaction called an A-minor motif. This is the first structure to reveal in great detail the geometry and hydration of a GUAA tetraloop and an A-minor motif. Comparison of tetraloop structures shows a common backbone geometry for each of the eight possible tetraloop sequences and suggests a common hydration. After backbone atom superposition, equivalent bases from different tetraloops unexpectedly depart from coplanarity by as much as 48°. This variation displaces the functional groups of tetraloops implicated in protein and RNA binding, providing a recognition feature. PMID:12592009

  13. Common and distinctive features of GNRA tetraloops based on a GUAA tetraloop structure at 1.4 A resolution.

    PubMed

    Correll, Carl C; Swinger, Kerren

    2003-03-01

    GNRA tetraloops (N is A, C, G, or U; R is A or G) are basic building blocks of RNA structure that often interact with proteins or other RNA structural elements. Understanding sequence-dependent structural variation among different GNRA tetraloops is an important step toward elucidating the molecular basis of specific GNRA tetraloop recognition by proteins and RNAs. Details of the geometry and hydration of this motif have been based on high-resolution crystallographic structures of the GRRA subset of tetraloops; less is known about the GYRA subset (Y is C or U). We report here the structure of a GUAA tetraloop determined to 1.4 A resolution to better define these details and any distinctive features of GYRA tetraloops. The tetraloop is part of a 27-nt structure that mimics the universal sarcin/ricin loop from Escherichia coli 23S ribosomal RNA in which a GUAA tetraloop replaces the conserved GAGA tetraloop. The adenosines of the GUAA tetraloop form an intermolecular contact that is a commonplace RNA tertiary interaction called an A-minor motif. This is the first structure to reveal in great detail the geometry and hydration of a GUAA tetraloop and an A-minor motif. Comparison of tetraloop structures shows a common backbone geometry for each of the eight possible tetraloop sequences and suggests a common hydration. After backbone atom superposition, equivalent bases from different tetraloops unexpectedly depart from coplanarity by as much as 48 degrees. This variation displaces the functional groups of tetraloops implicated in protein and RNA binding, providing a recognition feature.

  14. Structure of β-1,4-mannanase from the common sea hare Aplysia kurodai at 1.05 Å resolution

    PubMed Central

    Mizutani, Kimihiko; Tsuchiya, Sae; Toyoda, Mayuko; Nanbu, Yuko; Tominaga, Keiko; Yuasa, Keizo; Takahashi, Nobuyuki; Tsuji, Akihiko; Mikami, Bunzo

    2012-01-01

    β-1,4-Mannanase (EC 3.2.1.78) catalyzes the hydrolysis of β-1,4-glycosidic bonds within mannan, a major constituent group of the hemicelluloses. Bivalves and gastropods possess β-1,4-mannanase and may degrade mannan in seaweed and/or phytoplankton to obtain carbon and energy using the secreted enzymes in their digestive systems. In the present study, the crystal structure of AkMan, a gastropod β-1,4-mannanase prepared from the common sea hare Aplysia kurodai, was determined at 1.05 Å resolution. This is the first report of the three-dimensional structure of a gastropod β-1,4-mannanase. The structure was compared with bivalve β-1,4-mannanase and the roles of residues in the catalytic cleft were investigated. No obvious binding residue was found in subsite +1 and the substrate-binding site was exposed to the molecular surface, which may account for the enzymatic properties of mannanases that can digest complex substrates such as glucomannan and branched mannan. PMID:23027740

  15. Structure of β-1,4-mannanase from the common sea hare Aplysia kurodai at 1.05 Å resolution.

    PubMed

    Mizutani, Kimihiko; Tsuchiya, Sae; Toyoda, Mayuko; Nanbu, Yuko; Tominaga, Keiko; Yuasa, Keizo; Takahashi, Nobuyuki; Tsuji, Akihiko; Mikami, Bunzo

    2012-10-01

    β-1,4-Mannanase (EC 3.2.1.78) catalyzes the hydrolysis of β-1,4-glycosidic bonds within mannan, a major constituent group of the hemicelluloses. Bivalves and gastropods possess β-1,4-mannanase and may degrade mannan in seaweed and/or phytoplankton to obtain carbon and energy using the secreted enzymes in their digestive systems. In the present study, the crystal structure of AkMan, a gastropod β-1,4-mannanase prepared from the common sea hare Aplysia kurodai, was determined at 1.05 Å resolution. This is the first report of the three-dimensional structure of a gastropod β-1,4-mannanase. The structure was compared with bivalve β-1,4-mannanase and the roles of residues in the catalytic cleft were investigated. No obvious binding residue was found in subsite +1 and the substrate-binding site was exposed to the molecular surface, which may account for the enzymatic properties of mannanases that can digest complex substrates such as glucomannan and branched mannan.

  16. Rotational Analysis of Bands in the High-Resolution Infrared Spectra of cis,cis- and trans,trans-1,4-difluorobutadiene-2-d1

    SciTech Connect

    Craig, Norman C.; Easterday, Clay C.; Nemchick, Deacon J.; Williamson, Drew; Sams, Robert L.

    2012-02-01

    Pure samples of cis,cis- and trans,trans-1,4-difluorobutadiene-2-d1 have been synthesized, and high-resolution (0.0015 cm-1) infrared spectra have been recorded for these nonpolar molecules in the gas phase. For the cis,cis isomer, the rotational structure in two C-type bands at 775 and 666 cm-1 and one A-type band at 866 cm-1 has been analyzed to yield a combined set of 2020 ground state combination differences (GSCDs). Ground state rotational constants fit to these GSCDs are A0 = 0.4195790(4), B0 = 0.0536508(8), and C0 = 0.0475802(9) cm-1. For the trans,trans isomer, three Ctype bands at 856, 839, and 709 cm-1 have been investigated to give a combined set of 1624 GSCDs. Resulting ground state rotational constants for this isomer are A0 = 0.9390117(8), B0 = 0.0389225(4), and C0 = 0.0373778(3) cm-1. Small inertial defects confirm the planarity of both isomers in the ground state. Upper state rotational constants have been determined for most of the transitions. The ground state rotational constants for the two isotopologues will contribute to the data set needed for determining semiexperimental equilibrium structures for the nonpolar isomers of 1,4- difluorobutadiene.

  17. Construction of a High Temporal-spectral Resolution Spectrometer for Detection of Fast Transients from Observations of the Sun at 1.4 GHz.

    NASA Astrophysics Data System (ADS)

    Casillas-Perez, G. A.; Jeyakumar, S.; Perez-Enriquez, R.

    2014-12-01

    Transients explosive events with time durations from nanoseconds to several hours, are observed in the Sun at high energy bands such as gamma ray and xray. In the radio band, several types of radio bursts are commonly detected from the ground. A few observations of the Sun in the past have also detected a new class of fast transients which are known to have short-live electromagnetic emissions with durations less than 100 ms. The mechanisms that produce such fast transiets remain unclear. Observations of such fast transients over a wide bandwidth is necessary to uderstand the underlying physical process that produce such fast transients. Due to their very large flux densities, fast radio transients can be observed at high time resolution using small antennas in combination with digital signal processing techniques. In this work we report the progress of an spectrometer that is currently in construction at the Observatorio de la Luz of the Universidad de Guanajuato. The instrument which will have the purpose of detecting solar fast radio transients, involves the use of digital devices such as FPGA and ADC cards, in addition with a receiver with high temporal-spectral resolution centered at 1.4 GHz and a pair of 2.3 m satellite dish.

  18. Miles for Motivation.

    ERIC Educational Resources Information Center

    Roessing, Lesley

    2003-01-01

    Considers how to transfer a community fund-raising motivational tool to the classroom. Describes the Hoppin' Frog Contest, a project in which students work to earn "miles" instead of working for grades. (SG)

  19. A resolution congratulating the Cumberland Valley Athletic Club on the 48th anniversary of the running of the JFK 50-Mile Ultra-Marathon.

    THOMAS, 111th Congress

    Sen. Cardin, Benjamin L. [D-MD

    2010-08-05

    11/19/2010 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (text: CR S8205) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  20. Miles Hand Grenade

    DOEpatents

    Harrington, John J.; Buttz, James H.; Maish, Alex B.; Page, Ray R.; Metcalf, Herbert E.

    2005-11-15

    A simulated grenade for MILES-type simulations generates a unique RF signal and a unique audio signal. A detector utilizes the time between receipt of the RF signal and the slower-traveling audio signal to determine the distance between the detector and the simulated grenade.

  1. Effects of decreasing resolution on spectral and spatial information content in an agricultural area. [Pottawatmie study site, Iowa and Nebraska

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The effects of decreasing spatial resolution from 6 1/4 miles square to 50 miles square are described. The effects of increases in cell size is studied on; the mean and variance of spectral data; spatial trends; and vegetative index numbers. Information content changes on cadastral, vegetal, soil, water and physiographic information are summarized.

  2. A All-Vacuum High Resolution Fourier Transform Spectrometer with Absorption Pathlengths up to 352 M: Acetylene Spectrum at 1.4-1.7 Microns.

    NASA Astrophysics Data System (ADS)

    Keppler, Karen Ann

    1995-01-01

    The spectra of acetylene (C_2H _2) and of water vapor have been recorded at room temperature with Doppler- or pressure -broadening-limited resolution at pathlengths up to 352m. The spectra were obtained with the combination of a FTIR (Fourier Transform Infrared) spectrometer, evacuated transfer optics, and a multipass cell of 4m base length. The measurements were performed at the Justus-Liebig-Universitat in Giessen, Germany, using the FTIR spectrometer at that university, the multipass cell assembled at The Ohio State University, and the vacuum transfer optics designed by the author. The regions in which the spectra were recorded are 5900-7150 cm^{-1} and 1850-6600 cm^{-1}. Calibration difficulties pertaining to the determination of the absolute accuracy of the data have been resolved, and molecular parameters have been extracted for the HCCH data. These calibration problems were not documented in earlier studies using high resolution Fourier transform spectrometers. For this reason, the dissertation addresses this matter in somewhat greater detail. This work contains a description of the technology used to obtain the data, and a description of the calibration of the spectra to make them suitable for future use as secondary wavenumber calibration standards. The bands detected for the first time in this study have been reported, and updated energy level diagrams for HCCH and H^{13}CCH have been included. The molecular parameters obtained from the HCCH spectra have been presented. The appendices include, among others, the basic observational data, a spectral map and associated wavenumber lists of HCCH, and a description of the weighting scheme developed by the author for Fourier Transform spectra.

  3. Three-dimensional structures of unligated uridine phosphorylase from Yersinia pseudotuberculosis at 1.4 Å resolution and its complex with an antibacterial drug

    NASA Astrophysics Data System (ADS)

    Balaev, V. V.; Lashkov, A. A.; Gabdulkhakov, A. G.; Dontsova, M. V.; Mironov, A. S.; Betzel, C.; Mikhailov, A. M.

    2015-07-01

    Uridine phosphorylases play an essential role in the cellular metabolism of some antibacterial agents. Acute infectious diseases (bubonic plague, yersiniosis, pseudotuberculosis, etc., caused by bacteria of the genus Yersinia) are treated using both sulfanilamide medicines and antibiotics, including trimethoprim. The action of an antibiotic on a bacterial cell is determined primarily by the character of its interactions with cellular components, including those which are not targets (for example, with pyrimidine phosphorylases). This type of interaction should be taken into account in designing drugs. The three-dimensional structure of uridine phosphorylase from the bacterium Yersinia pseudotuberculosis ( YptUPh) with the free active site was determined for the first time by X-ray crystallography and refined at 1.40 Å resolution (DPI = 0.062 Å; ID PDB: 4OF4). The structure of the complex of YptUPh with the bacteriostatic drug trimethoprim was studied by molecular docking and molecular dynamics methods. The trimethoprim molecule was shown to be buffered by the enzyme YptUPh, resulting in a decrease in the efficiency of the treatment of infectious diseases caused by bacteria of the genus Yersinia with trimethoprim.

  4. The Three Mile Island Disaster.

    ERIC Educational Resources Information Center

    Crosby, Emeral

    1980-01-01

    For the past decade, education has been experiencing meltdown, explosions, radiation leaks, heat pollution, and management crises, just like the Three Mile Island disaster. This article offers suggestions on how to deal with these problems. (Author/LD)

  5. Miles Pickering--A Bibliography.

    ERIC Educational Resources Information Center

    Kandel, Marjorie

    1998-01-01

    Miles Pickering joined the Princeton University staff in 1976, became director of the undergraduate chemistry laboratories in 1981, and was a chemistry department lecturer and senior staff member until he died in 1991. Focuses on his inspiring publications in the "Journal of College Science Teaching" and the "Journal of Chemical Education."…

  6. 1,4-Dibromobenzene

    Integrated Risk Information System (IRIS)

    1,4 - Dibromobenzene ; CASRN 106 - 37 - 6 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinoge

  7. 1,4-Dichlorobenzene

    Integrated Risk Information System (IRIS)

    1,4 - Dichlorobenzene ; CASRN 106 - 46 - 7 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinog

  8. 1,4-Dioxane

    Integrated Risk Information System (IRIS)

    EPA / 635 / R - 09 / 005 - F www.epa.gov / iris TOXICOLOGICAL REVIEW OF 1,4 - Dioxane ( CAS No . 123 - 91 - 1 ) In Support of Summary Information on the Integrated Risk Information System ( IRIS ) August 2010 U.S . Environmental Protection Agency Washington , DC DISCLAIMER This document has been rev

  9. 1,4-Dithiane

    Integrated Risk Information System (IRIS)

    1,4 - Dithiane ; CASRN 505 - 29 - 3 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcinogenic Ef

  10. Asian-Pacific Islander Profile - Wason MIles

    NASA Video Gallery

    Wason Miles brought two decades of experience as a life-support technician in the U.S. Air Force when he joined the staff of NASA's Dryden Flight Research Center in 2009. Miles, a native of Hawai'i...

  11. Performance differences between sexes in 50-mile to 3,100-mile ultramarathons

    PubMed Central

    Zingg, Matthias A; Knechtle, Beat; Rosemann, Thomas; Rüst, Christoph A

    2015-01-01

    Anecdotal reports have assumed that women would be able to outrun men in long-distance running. The aim of this study was to test this assumption by investigating the changes in performance difference between sexes in the best ultramarathoners in 50-mile, 100-mile, 200-mile, 1,000-mile, and 3,100-mile events held worldwide between 1971 and 2012. The sex differences in running speed for the fastest runners ever were analyzed using one-way analysis of variance with subsequent Tukey–Kramer posthoc analysis. Changes in sex difference in running speed of the annual fastest were analyzed using linear and nonlinear regression analyses, correlation analyses, and mixed-effects regression analyses. The fastest men ever were faster than the fastest women ever in 50-mile (17.5%), 100-mile (17.4%), 200-mile (9.7%), 1,000-mile (20.2%), and 3,100-mile (18.6%) events. For the ten fastest finishers ever, men were faster than women in 50-mile (17.1%±1.9%), 100-mile (19.2%±1.5%), and 1,000-mile (16.7%±1.6%) events. No correlation existed between sex difference and running speed for the fastest ever (r2=0.0039, P=0.91) and the ten fastest ever (r2=0.15, P=0.74) for all distances. For the annual fastest, the sex difference in running speed decreased linearly in 50-mile events from 14.6% to 8.9%, remained unchanged in 100-mile (18.0%±8.4%) and 1,000-mile (13.7%±9.1%) events, and increased in 3,100-mile events from 12.5% to 16.9%. For the annual ten fastest runners, the performance difference between sexes decreased linearly in 50-mile events from 31.6%±3.6% to 8.9%±1.8% and in 100-mile events from 26.0%±4.4% to 24.7%±0.9%. To summarize, the fastest men were ~17%–20% faster than the fastest women for all distances from 50 miles to 3,100 miles. The linear decrease in sex difference for 50-mile and 100-mile events may suggest that women are reducing the sex gap for these distances. PMID:25653567

  12. 33 CFR 117.565 - Miles River.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Miles River. 117.565 Section 117.565 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Maryland § 117.565 Miles River. The draw of the Route...

  13. 33 CFR 117.565 - Miles River.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Miles River. 117.565 Section 117.565 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Maryland § 117.565 Miles River. The draw of the Route...

  14. 33 CFR 117.565 - Miles River.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Miles River. 117.565 Section 117.565 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Maryland § 117.565 Miles River. The draw of the Route...

  15. 33 CFR 117.565 - Miles River.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Miles River. 117.565 Section 117.565 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Maryland § 117.565 Miles River. The draw of the Route...

  16. 33 CFR 117.565 - Miles River.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Miles River. 117.565 Section 117.565 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Maryland § 117.565 Miles River. The draw of the Route...

  17. Miles In Trail (MIT) Restrictions: A Perspective

    NASA Technical Reports Server (NTRS)

    Kopardekar, Parimal; Green, Steven; Roherty, Tom; Aston, John

    2003-01-01

    Miles-in-trail restrictions are issued to meet the airport and/or airspace capacity. The purpose of this paper is to review the currently practiced miles-in-trail operations for traffic flow management at a typical en route Air Traffic Control Center. The paper describes roles and considerations of both traffic management coordinators and the controllers in planning, coordination, execution, and monitoring of miles-in-trail restrictions. The paper addresses the type of decisions that traffic management coordinators must make and the different information required to plan and monitor miles-in-trail restrictions. The implications of miles-in-trail restrictions on controller workload are also addressed. Using the Cleveland center as an example, the paper also identified some challenging traffic situations that required miles-in-trail restrictions on a regular basis. The paper is expected to benefit the research and development community as it provides the current challenges in traffic flow management and strengths and weakness of miles-in-trail operations.

  18. In the Shadow of Three Mile Island.

    ERIC Educational Resources Information Center

    Blair-Clough, Ida; Wheeler, Brenda

    1979-01-01

    Describes how teachers turned the reality of the nuclear reactor incident at Three Mile Island into a learning experience for children by recreating the sequence of events through creative dramatics. (CM)

  19. A Chemistry Lesson at Three Mile Island.

    ERIC Educational Resources Information Center

    Mammano, Nicholas J.

    1980-01-01

    Details the procedures used in utilizing the hydrogen bubble incident at Three Mile Island to relate these basic chemical principles to nuclear chemistry: gas laws, Le Chatelier's principle and equilibrium, and stoichiometry. (CS)

  20. 78 FR 36660 - Safety Zone; Mississippi River Mile 95.5-Mile 96.5; New Orleans, LA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River Mile 95.5-Mile 96.5; New... establishing a temporary safety zone for all waters of the Lower Mississippi River from mile 95.5 to mile 96.5... with a fireworks display in the Lower Mississippi River at mile 96. Entry into this zone is...

  1. Miles Discusses Skylab Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Lexington, Massachusetts high school student, Judith Miles, discusses her proposed Skylab experiment with engineers and scientists during a design review of the experiment equipment. At left is Ron Pavlue of Kennedy Space Flight Center (KSC), holding a box is Keith Demorest of Marshall Space Flight Center (MSFC). Right of Miles is Dr. Raymond Gause, also of MSFC, who is Miles' scientific advisor. In her experiment, called the 'Web Formation in Zero Gravity', spiders were released into a box and their actions recorded to determine how well they adapt to the absence of gravity. Spiders are known to adapt quickly to other changes in the environment but nothing was known of their ability to adapt to weightlessness. At the same time spiders were weaving webs in Earth orbit, similar spiders were spinning webs in identical boxes on Earth under full gravity conditions. Miles was among the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  2. Good Engineering + Poor Communication = Three Mile Island.

    ERIC Educational Resources Information Center

    Mathes, J. C.

    The accident at the Three Mile Island nuclear power plant resulted from a communication failure. Following an incident at an Ohio plant a year and a half earlier, B. M. Dunn, manager of Emergency Core Cooling Systems Analysis at Babcock and Wilcox (engineers), wrote a memorandum making specific recommendations on written instructions for nuclear…

  3. Normal Accident at Three Mile Island.

    ERIC Educational Resources Information Center

    Perrow, Charles

    1981-01-01

    Discusses some aspects of the accident at the Three Mile Island nuclear power plant. Explains a number of factors involved including the type of accident, warnings, design and equipment failure, operator error, and negative synergy. Presents alternatives to systems with catastrophic potential. (MK)

  4. One Half Million Mile Solar Filament

    NASA Video Gallery

    NASA’s Solar Dynamics Observatory (SDO) captures a very long, whip-like solar filament extending over half a million miles in a long arc above the sun’s surface. Filaments are cooler clouds of ...

  5. The Three Mile Island Population Registry.

    PubMed Central

    Goldhaber, M K; Tokuhata, G K; Digon, E; Caldwell, G G; Stein, G F; Lutz, G; Gur, D

    1983-01-01

    Shortly after the March 28, 1979, accident at the Three Mile Island (TMI) nuclear plant outside Harrisburg, Pa., the Pennsylvania Department of Health, in conjunction with the Centers for Disease Control and the U.S. Bureau of the Census, conducted a census of the 35,930 persons residing within 5 miles of the plant. With the help of 150 enumerators, demographic and health-related information was collected on each person to provide baseline data for future short- and long-term epidemiologic studies of the effects of the accident. Individual radiation doses were estimated on the basis of residential location and the amount of time each person spent in the 5-mile area during the 10 days after the accident. Health and behavioral resurveys of the population will be conducted approximately every 5 years. Population-mobility, morbidity, and mortality will be studied yearly by matching the TMI Population Registry with postal records, cancer registry records, and death certificate data. Because the radiation dose from TMI was extremely small, any increase in morbidity or mortality attributable to the accident would be so small as not to be measurable by present methods; however, adverse health effects as a result of psychological stress may occur. Also, a temporary increase in reporting of disease could occur because of increased surveillance and attention to health. PMID:6419276

  6. Three Mile Island Commission and the language of legitimacy

    SciTech Connect

    Fingrutd, M.A.

    1984-01-01

    This work is an exploration in discourse. It assumes that discourse is constitutive of and constituted by social organization. The research site for this investigation is provided by transcripts from the President's Commission to investigate the accident at Three Mile Island. The transcripts cover five days of meetings where 12 Commissioners discussed the content, nuance, tone and scope of the report they would submit to the President. The analytical goal of the research is to understand four features of the dialogue: (1) formal structure of conversation: how utterances are organized into an orderly, rational, meaningful conversation; (2) meaning or content of the talk; (3) the way conversational form and content act together to create a form of rationality or orientation to task and (4) social context surrounding the talk. The approach to the transcripts relies upon a variety of discourse analysis techniques in order to examine four essential disputes - places of deep level disagreement among the Commissioners. For each dispute, the forces that constrained and/or compelled the dialogue toward resolution are noted. The work concludes by asserting that the linguistic practices used by the Commissioners indicate a techno-bureaucratic approach to understanding the accident at Three Mile Island and formulating recommendations for public policy toward nuclear power.

  7. 29. VIEW OF STONE BUILDING, ABOUT ONE MILE DOWNSTREAM OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. VIEW OF STONE BUILDING, ABOUT ONE MILE DOWNSTREAM OF DAM, USED TO STORE EXPLOSIVES DURING THE CONSTRUCTION OF HORSE MESA - Horse Mesa Dam, Salt River, 65 miles East of Phoenix, Phoenix, Maricopa County, AZ

  8. Detail of decorative panel featuring a monkey at Ten Mile ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of decorative panel featuring a monkey at Ten Mile River Playground comfort station, looking northwest. - Henry Hudson Parkway, Extending 11.2 miles from West 72nd Street to Bronx-Westchester border, New York County, NY

  9. Astronomy for Mile-Hi Girl Scouts

    NASA Astrophysics Data System (ADS)

    Morrow, C. A.; Fuller, L.

    1999-12-01

    The Space Science Institute engaged Denver area astronomers in collaboration with the Girl Scouts - Mile Hi Council to plan, implement, and evaluate workshops on astronomy and Mars exploration for Junior Girl Scouts (ages 9-11) and their Troop Leaders. We designed a workshop for the Scouts that would enable them to earn their Sky Watch badge. In addition we implemented a workshop for Troop Leaders who want to implement badge-related space science activities within their troops. This talk (or poster) will report on our experiences and lessons learned in these workshops. Our work was supported by the NASA IDEAS program.

  10. Miles Discusses Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Lexington, Massachusetts high school student, Judith Miles, discusses her proposed Skylab experiment with Keith Demorest (right) and Henry Floyd, both of Marshall Space Flight Center (MSFC). In her experiment, called the 'Web Formation in Zero Gravity', called for spiders to be released into a box and their actions recorded to determine how well they adapt to the absence of gravity. Spiders are known to adapt quickly to other changes in the environment but nothing was known of their ability to adapt to weightlessness. At the same time spiders were weaving webs in Earth orbit, similar spiders were spinning webs in identical boxes on Earth under full gravity conditions. Miles was among the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab Mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  11. 78 FR 35567 - Safety Zone; Lower Mississippi River, Mile Marker 219 to Mile Marker 229, in the Vicinity of Port...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Lower Mississippi River, Mile Marker 219 to... Mississippi River beginning at mile marker 219 and ending at mile marker 229, extending the entire width of.... The water levels on the Lower Mississippi River in this area have risen very rapidly, creating...

  12. Predicting One Mile and Two Mile Run Performance from Physiological Measures.

    ERIC Educational Resources Information Center

    Sucec, A. A.

    Twenty-three male distance runners between the ages of 16 and 23 who had achieved a ten-minute or better two-mile performance were tested to determine physical and physiological characteristics to be used in predictive research regarding running performance. Relative body fat ratio, metabolic data, and oxygen intake capability were among the…

  13. Three Mile Island: meltdown of democracy

    SciTech Connect

    Walsh, E.J.

    1983-03-01

    Strong local opposition to a start-up of Unit 1 at Three Mile Island continues because citizen distrust of General Public Utilities was found in post-accident studies to have been justified. Several citizen groups have monitored the Unit 2 clean-up activities and have not been reassured by either the President's Commission or the Nuclear Regulatory Commission. Efforts to improve public relations by distributing radiation kits or other strategies have been outweighed by evidence of government manipulation of early bomb test data and poor industry planning. Arguments over who is responsible for the accident and who is liable for the cost have further undermined credibility. Area residents have received three recent legal signals that their position may prevail. (DCK)

  14. Entiat 4Mile WELLs Completion Report, 2006.

    SciTech Connect

    Malinowksi, Richard

    2007-01-01

    The Entiat 4-mile Wells (Entiat 4-mile) project is located in the Entiat subbasin and will benefit Upper Columbia steelhead, spring Chinook and bull trout. The goal of this project is to prevent juvenile fish from being diverted into an out-of-stream irrigation system and to eliminate impacts due to the annual maintenance of an instream pushup dam. The objectives include eliminating a surface irrigation diversion and replacing it with two wells, which will provide Bonneville Power Administration (BPA) and the Bureau of Reclamation (Reclamation) with a Federal Columbia River Power System (FCRPS) BiOp metric credit of one. Wells were chosen over a new fish screen based on biological benefits and costs. Long-term biological benefits are provided by completely eliminating the surface diversion and the potential for fish entrainment in a fish screen. Construction costs for a new fish screen were estimated at $150,000, which does not include other costs associated with implementing and maintaining a fish screening project. Construction costs for a well were estimated at $20,000 each. The diversion consisted of a pushup dam that diverted water into an off-channel pond. Water was then pumped into a pressurized system for irrigation. There are 3 different irrigators who used water from this surface diversion, and each has multiple water right claims totaling approximately 5 cfs. Current use was estimated at 300 gallons per minute (approximately 0.641 cfs). Some irrigated acreage was taken out of orchard production less than 5 years ago. Therefore, approximately 6.8 acre-feet will be put into the State of Washington Trust Water Right program. No water will be set aside for conservation savings. The construction of the two irrigation wells for three landowners was completed in September 2006. The Lower Well (Tippen/Wick) will produce up to 175 gpm while the Upper Well (Griffith) will produce up to 275 gpm during the irrigation season. The eight inch diameter wells were

  15. Nuclear power beyond Three Mile Island

    SciTech Connect

    Rowlette, J.

    1980-05-01

    At the Three Mile Island-2 Reactor accident in March, 1979, there was concern expressed over a chemical explosion that might rupture the containment vessel and release radioactive material. The absolute worst possible event that could take place at a nuclear power plant would be a melt-down that breached the containment vessel and allowed radioactive material to escape, but this absolute worst possible case would create less cost and loss of life than many natural disasters. When the anti-nukes talk about a nuclear power plant devastating an area the size of Pennsylvania or California, and leaving a vast wasteland for 10,000 years, they are being grossly dishonest, for even at Hiroshima and Nagasaki, where we exploded weapons with the intent of massive destruction, the area has been completely restored and repopulated. The only major threat from nuclear power plant accidents is radiation. The average radiation dose received by every American each year is 170 millirems-130 from natural radiation and 40 millirems from man-made sources. A summary of the risks encountered from the combustion of coal, watching TV, diagnostic x-rays, dams collapsing, etc. making the risk level from nuclear radiation much smaller than most secular activities, is given.

  16. 10. VIEW OF PIPING. THE BUILDING HAD OVER 700 MILES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. VIEW OF PIPING. THE BUILDING HAD OVER 700 MILES OF PIPING, OF WHICH 70 MILES WERE PLUTONIUM PROCESSING LINES. THESE PROCESS LINES RAN THROUGH WALLS AND TRAVERSED SEVERAL FLOORS. (6/29/78) - Rocky Flats Plant, Plutonium Recovery Facility, Northwest portion of Rocky Flats Plant, Golden, Jefferson County, CO

  17. Chronic Stress and Three Mile Island: Toxic Exposure and Uncertainty.

    ERIC Educational Resources Information Center

    Davidson, Laura M.; And Others

    Although many researchers expected the psychological effects of the accident at the Three Mile Island (TMI) nuclear plant to be short-lived, area residents continued to show elevated levels of stress. To examine stress levels of TMI residents 28 months after the accident, 141 subjects were chosen from nearby areas, and from a town 80 miles away.…

  18. 9. MILE ROCK TUNNEL DURING EXCAVATION OF OPEN CUT PORTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. MILE ROCK TUNNEL DURING EXCAVATION OF OPEN CUT PORTION IN 1915. DEPARTMENT OF PUBLIC WORKS, MAP AND PLAN ROOM, PHOTO #2513. - Mile Rock Tunnel, Under Forty-eighth Avenue from Cabrillo Street to San Francisco Bay at Point Lobos, San Francisco, San Francisco County, CA

  19. 14 CFR 73.5 - Bearings; radials; miles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Bearings; radials; miles. 73.5 Section 73.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SPECIAL USE AIRSPACE General § 73.5 Bearings; radials; miles. (a) All bearings and radials in this...

  20. 14 CFR 73.5 - Bearings; radials; miles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Bearings; radials; miles. 73.5 Section 73.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SPECIAL USE AIRSPACE General § 73.5 Bearings; radials; miles. (a) All bearings and radials in this...

  1. 14 CFR 73.5 - Bearings; radials; miles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Bearings; radials; miles. 73.5 Section 73.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SPECIAL USE AIRSPACE General § 73.5 Bearings; radials; miles. (a) All bearings and radials in this...

  2. 14 CFR 73.5 - Bearings; radials; miles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Bearings; radials; miles. 73.5 Section 73.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SPECIAL USE AIRSPACE General § 73.5 Bearings; radials; miles. (a) All bearings and radials in this...

  3. 14 CFR 73.5 - Bearings; radials; miles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Bearings; radials; miles. 73.5 Section 73.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE SPECIAL USE AIRSPACE General § 73.5 Bearings; radials; miles. (a) All bearings and radials in this...

  4. 33 CFR 117.115 - Three Mile Creek.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Three Mile Creek. 117.115 Section 117.115 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Alabama § 117.115 Three Mile Creek. (a) The draw...

  5. 13. INTERIOR OF MILE ROCK TUNNEL, COMPLETED AND READY FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. INTERIOR OF MILE ROCK TUNNEL, COMPLETED AND READY FOR FINAL INSPECTION, AUGUST 1915. Department of Public Works, Map and Plan Room, photo #2512. - Mile Rock Tunnel, Under Forty-eighth Avenue from Cabrillo Street to San Francisco Bay at Point Lobos, San Francisco, San Francisco County, CA

  6. 50 CFR 1.4 - Director.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Director. 1.4 Section 1.4 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS § 1.4 Director. Director means the Director, U.S. Fish and Wildlife Service or the...

  7. 21 CFR 1.4 - Authority citations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Authority citations. 1.4 Section 1.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS General Provisions § 1.4 Authority citations. (a) For each part of its regulations, the Food...

  8. 21 CFR 1.4 - Authority citations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Authority citations. 1.4 Section 1.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS General Provisions § 1.4 Authority citations. (a) For each part of its regulations, the Food...

  9. 45 CFR 1206.1-4 - Suspension.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Suspension. 1206.1-4 Section 1206.1-4 Public... GRANTS AND CONTRACTS-SUSPENSION AND TERMINATION AND DENIAL OF APPLICATION FOR REFUNDING Suspension and Termination of Assistance § 1206.1-4 Suspension. (a) General. The responsible Corporation official may...

  10. 45 CFR 1211.1-4 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Policy. 1211.1-4 Section 1211.1-4 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-4 Policy. It is ACTION's policy to provide volunteers the widest latitude...

  11. 45 CFR 1211.1-4 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Policy. 1211.1-4 Section 1211.1-4 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-4 Policy. It is ACTION's policy to provide volunteers the widest latitude to present their grievances...

  12. 45 CFR 1216.1-4 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Exceptions. 1216.1-4 Section 1216.1-4 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE NONDISPLACEMENT OF EMPLOYED WORKERS AND NONIMPAIRMENT OF CONTRACTS FOR SERVICE § 1216.1-4 Exceptions. (a) The requirements of § 1216.1-3 are...

  13. 76 FR 60733 - Safety Zone; Mississippi River, Mile Marker 230 to Mile Marker 234, in the Vicinity of Baton...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River, Mile Marker 230 to Mile.... SUMMARY: The Coast Guard is establishing a temporary safety zone for all waters of the Mississippi River... to 234, Lower Mississippi River to protect those vessels and mariners from the hazards...

  14. 78 FR 77592 - Safety Zone; Lower Mississippi River Mile 94.1-Mile 95.1; New Orleans, LA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Lower Mississippi River Mile 94.1-Mile 95.1; New Orleans, LA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is... Information The Coast Guard is issuing this final rule without prior notice and opportunity to...

  15. High Resolution Orientation Imaging Microscopy

    DTIC Science & Technology

    2012-05-02

    Functions, ICCES 2010, Las Vegas. 17. David Fullwood, Brent Adams, Mike Miles, Stuart Rogers, Ali Khosravani, Raj Mishra, Design for Ductility : Defect... Pseudo -Symmetries by High Resolution EBSD Methods, MS&T. 2009: Pittsburgh. 27. Oliver Johnson, Calvin Gardner, David Fullwood, Brent Adams, George...applied to strain measurements ................................... 6 2.3 Recovery of Lattice Tetragonality and Pseudo -Symmetry Resolution

  16. 4. VIEW SHOWING EXCAVATION IN ARIZONA CANAL, 8 MILES NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW SHOWING EXCAVATION IN ARIZONA CANAL, 8 MILES NORTHEAST OF PHOENIX. NOTE MEN DRILLING AND EXCAVATING IN OPERATION; CAMELBACK MOUNTAIN IN THE DISTANCE Photographer: Walter J. Lubken. No date - Arizona Canal, North of Salt River, Phoenix, Maricopa County, AZ

  17. 88. (Credit CBF) Twelve Mile Bayou Pumping Station and force ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    88. (Credit CBF) Twelve Mile Bayou Pumping Station and force main for pumping water over levee and into the canal (Blind Bayou), March 1913. - McNeil Street Pumping Station, McNeil Street & Cross Bayou, Shreveport, Caddo Parish, LA

  18. Big Creek Hydroelectric System, East & West Transmission Line, 241mile ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Big Creek Hydroelectric System, East & West Transmission Line, 241-mile transmission corridor extending between the Big Creek Hydroelectric System in the Sierra National Forest in Fresno County and the Eagle Rock Substation in Los Angeles, California, Visalia, Tulare County, CA

  19. 2. Historic American Buildings Survey Miles W. Beemer, Photographer c. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Miles W. Beemer, Photographer c. 1920 From right to left: Unidentified house, O'Gorman House, Carrington House, Mandeville House. - Broad Street, 900 Block (House), Newark, Essex County, NJ

  20. 24 CFR 1.4 - Discrimination prohibited.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Discrimination prohibited. 1.4... DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.4 Discrimination prohibited. (a... excluded from participation in, be denied the benefits of, or be otherwise subjected to...

  1. 24 CFR 1.4 - Discrimination prohibited.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Discrimination prohibited. 1.4... DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.4 Discrimination prohibited. (a... excluded from participation in, be denied the benefits of, or be otherwise subjected to...

  2. 24 CFR 1.4 - Discrimination prohibited.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Discrimination prohibited. 1.4... DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.4 Discrimination prohibited. (a... excluded from participation in, be denied the benefits of, or be otherwise subjected to...

  3. 24 CFR 1.4 - Discrimination prohibited.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Discrimination prohibited. 1.4... DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.4 Discrimination prohibited. (a... excluded from participation in, be denied the benefits of, or be otherwise subjected to...

  4. 21 CFR 1.4 - Authority citations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... statute is the Federal Food, Drug, and Cosmetic Act, the Public Health Service Act, or the Fair Packaging... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Authority citations. 1.4 Section 1.4 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL...

  5. 26 CFR 1.4-2 - Elections.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Elections. 1.4-2 Section 1.4-2 Internal Revenue....4-2 Elections. (a) Making of election. The election to pay the optional tax imposed under section 3... the standard deduction provided by section 141. (b) Election under section 3 and election of...

  6. 45 CFR 1206.1-4 - Suspension.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Suspension. 1206.1-4 Section 1206.1-4 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE GRANTS AND CONTRACTS-SUSPENSION AND TERMINATION AND DENIAL OF APPLICATION FOR REFUNDING Suspension and Termination of Assistance §...

  7. Health effects of the nuclear accident at Three Mile Island

    SciTech Connect

    Fabrikant, J.I.

    1980-05-01

    Between March 28 and April 15, 1979 the collective dose resulting from the radioactivity released to the population living within a 50-mile radius of the Three Mile Island nuclear plant was about 2000 person-rems, less than 1% of the annual natural background level. The average dose to a person living within 5 miles of the nuclear plant was less than 10% of annual background radiation. The maximum estimated radiation dose received by any one individual in the general population (excluding the nuclear plant workers) during the accident was 70 mrem. The doses received by the general population as a result of the accident were so small that there will be no detectable additional cases of cancer, developmental abnormalities, or genetic ill-health. Three Three Mile Island nuclear workers received radiation doses of about 3 to 4 rem, exceeding maximum permissible quarterly dose of 3 rem. The major health effect of the accident at Three Mile Island was that of a pronounced demoralizing effect on the general population in the Three Mile Island area, including teenagers and mothers of preschool children and the nuclear plant workers. However, this effect proved transient in all groups studied except the nuclear workers.

  8. Coordination chemistry of 1,4-bis-carboxymethylcyclam, H(2)(1,4-bcc).

    PubMed

    Tonei, Deborah M; Ware, David C; Brothers, Penelope J; Plieger, Paul G; Clark, George R

    2006-01-07

    Zinc metal reduction of the cobalt(III) complex [Co(1,4-bcc)](+) (1,4-bcc = 1,4-bis-carboxymethylcyclam) produces the corresponding cobalt(II) complex which crystallises as the coordination polymer {[Co(1,4-bcc)]ZnCl(2)}(n). A method has been developed for removal of the cobalt(III) ion from [Co(1,4-bcc)](+) and isolation of the free ligand as its hydrochloride salt, H(2)(1,4-bcc).4HCl. This has been used for the preparation of new metal complexes, and the syntheses and characterisation of the copper(ii), nickel(ii), zinc(ii) and chromium(iii) complexes containing the 1,4-bcc ligand are described. X-Ray crystal structures of {[Co(1,4-bcc)]ZnCl(2)}(n).2.5H(2)O, {[Cu(1,4-bcc)]CuCl(2)}(n).0.25MeOH.H(2)O and [Cu(1,4-bcc)H]ClO(4) show the complexes to have the trans(O) geometry of the 1,4-bcc ligand, while the structure of [Cr(1,4-bcc)H(0.5)](ClO(4))(1.5).EtOH exhibits the cis(O) configuration.

  9. Utilization of medical care following the Three Mile Island crisis

    SciTech Connect

    Houts, P.S.; Hu, T.W.; Henderson, R.A.; Cleary, P.D.; Tokuhata, G.

    1984-02-01

    Four studies are reported on how utilization of primary health care was affected by the Three Mile Island (TMI) crisis and subsequent distress experienced by persons living in the vicinity of the plant. The studies concerned: Blue Cross-Blue Shield records of claims by primary care physicians in the vicinity of TMI; utilization rates in a family practice located near the facility; interviews with persons living within five miles of TMI following the crisis; and responses to a questionnaire by primary care physicians practicing within 25 miles of TMI. All four studies indicated only slight increases in utilization rates during the year following the crisis. One study found that persons who were upset during the crisis tended to be high practice utilizers both before and after the crisis. These results suggest that, while patterns of physician utilization prior to the TMI crisis predicted emotional response during the crisis, the impact of the TMI crisis on subsequent physician utilization was small.

  10. Biodegradation of 1,4-Dioxane

    DTIC Science & Technology

    2007-08-01

    Pseudonocardia sp. strain K1 was used to hydrolyze diglycolic acid, the free radical generator phenazine methosulfate was included in the assay, as reported... phenazine methosulfate is not a physiologically relevant compound and can not be involved in 1,4-dioxane mineralization in vivo. III. D. Discussion of

  11. Heads from "Post" and "Times" on Three-Mile Island.

    ERIC Educational Resources Information Center

    Fenichel, Michael; Dan, Peter

    1980-01-01

    Reports that during the week of the 1979 crisis at the Three Mile Island nuclear power plant, the "New York Post" gave less factual information than "The New York Times" in both its main headlines and subheadlines; also notes that the information the "Post" did give was more sensationalized. (GT)

  12. The East European Press and Three-Mile Island.

    ERIC Educational Resources Information Center

    Johnson, Owen V.

    This report of the investigation into East European newspaper treatment of the accident at Pennsylvania's Three Mile Island nuclear power plant in the spring of 1979 focuses on the Czech and Slovak media, particularly on the Slovak Communist Party's daily newspaper, "Pravda." The response of the media of other East European countries to…

  13. Local Coverage of Three Mile Island during 1981-82.

    ERIC Educational Resources Information Center

    Friedman, Sharon M.

    Local newspaper coverage of the Three Mile Island (TMI) nuclear power plant accident was examined in a study to determine what changes, if any, were made by local media and what lessons they had learned from it. Data were collected through interviews with 21 media representatives. TMI coverage in the six newspapers was examined using each…

  14. 86. (Credit CBF) Canal between Twelve Mile Bayou and Cross ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    86. (Credit CBF) Canal between Twelve Mile Bayou and Cross Bayou in the bed of Blind Bayou (constructed 1901-1903). Photo taken in November of 1911. - McNeil Street Pumping Station, McNeil Street & Cross Bayou, Shreveport, Caddo Parish, LA

  15. 4. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W of Ms. 25 on dirt road 2.5 mi. N of Bull Mtn. Cr. View from N, wide angle. Sarcone Photography, Columbus, Ms. September 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  16. 5. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W of Ms. 25 on dirt road 2.5 mi. N of Bull Mtn. Cr. View of underside from NE shore, showing lower panel point, lateral bracing. Sarcone Photography, Columbus, Ms. September 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  17. 3. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W of Ms. 25 on dirt road 2.5 mi. N of Bull Mtn. Cr. View from S side of E approach. Sarcone Photography, Columbus, Ms. September 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  18. 2. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. IRONWOOD BLUFFS BRIDGE MISSISSIPPI, ITAWAMBA CO. One mile W of Ms. 25 on dirt road 2.5 mi. N of Bull Mtn. Cr. Oblique view of N truss from E end. Sarcone Photography, Columbus, Ms. September 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  19. 10. RAILROAD BRIDGE MISSISSIPPI, MONROE CO., AMORY Onehalf mile S ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. RAILROAD BRIDGE MISSISSIPPI, MONROE CO., AMORY One-half mile S of MS. 6, 1.5. mi. NW of Amory. Aerial view from SE, of St. Louis and San Francisco Railroad bridge. David Kaminsky, Architectural Photography, Atlanta Ga. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  20. Biology and Biological Control of Mile-a-Minute Weed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Mile-a-minute weed (MAM), Persicaria perfoliata (L.) H. Gross (Fig. 1), is a member of the family Polygonaceae. It is an annual vine that can grow up to 6 meters long over the course of a season. It is widely distributed throughout east Asia, including Japan, China, Korea, India, Indonesia, Banglade...

  1. Margaret Miles: The Educational Journey of a Comprehensive School Campaigner

    ERIC Educational Resources Information Center

    Hoare, Lottie

    2012-01-01

    As a former comprehensive school pupil herself, the author wanted to know more about the women who had pioneered comprehensive schools in England. Therefore, she chose the headmistress and comprehensive school campaigner Dame Margaret Miles (1911-1994) as the subject of a dissertation for her History of Education MA at the Institute of Education,…

  2. Prince William Forest Park American Beech , Approximately one mile ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Prince William Forest Park American Beech , Approximately one mile from visitor’s center, south bank of the south fork of Quantico Creek, about 75 yards upstream from its confluence with Quantico Creek, Near Birch Bluff Trail, Triangle, Prince William County, VA

  3. Detail Hframe structure about five and onefourth miles southwest of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail H-frame structure about five and one-fourth miles southwest of Morony Dam and Powerhouse showing one modern non-ceramic insulator and two historic porcelain suspension insulators - Morony Hydroelectric Facility, Morony-to-Rainbow 100 kV Transmission Line, West bank of the Missouri River, Great Falls, Cascade County, MT

  4. 1. Historic American Buildings Survey Miles W. Beemer, Photographer c. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Miles W. Beemer, Photographer c. 1920 From right to left: Alta House, unidentified house, O'Gorman House, Carrington House, Mandeville House, unidentified house, Richter House, two unidentified houses, Hedges House. - Broad Street, 900 Block (House), Newark, Essex County, NJ

  5. 77 FR 39170 - Safety Zone; Mississippi River, Mile Marker 230.0 to Mile Marker 237.0, in the Vicinity of Baton...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River, Mile Marker 230.0 to... Mississippi River (LMR) beginning at mile marker (MM) 230.0 and ending at MM 237.0, in the vicinity of Baton... of Proposed Rulemaking LMR Lower Mississippi River MM Mile Marker A. Regulatory History...

  6. Photographer: JPL P-21740 BW Range: 2,318,000 kilometers (1,438,000 miles) This picture of Callisto

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Photographer: JPL P-21740 BW Range: 2,318,000 kilometers (1,438,000 miles) This picture of Callisto taken by Voyager 2 shows the moon covered with bright spots which are metoerite impact craters--a fact originally discovered from the high resolution pictures taken by Voyager 1. Scientists believe that heavily cratered terrains like these on Callisto are indicative of ancient planetary surfaces. Voyager 2 mapped the side of Callisto not seen by Voyager 1. The obsure dark streaks in this area may be fault zones, but higher resolution pictures are needed for identification.

  7. Photographer: JPL P-21740 C Range: 2,318,000 kilometers (1,438,000 miles) This picture of Callisto

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Photographer: JPL P-21740 C Range: 2,318,000 kilometers (1,438,000 miles) This picture of Callisto taken by Voyager 2 shows the moon covered with bright spots which are metoerite impact craters--a fact originally discovered from the high resolution pictures taken by Voyager 1. Scientists believe that heavily cratered terrains like these on Callisto are indicative of ancient planetary surfaces. Voyager 2 mapped the side of Callisto not seen by Voyager 1. The obsure dark streaks in this area may be fault zones, but higher resolution pictures are needed for identification.

  8. 7. Photocopy of photographca. 1927 (2 1/4 X 2 1/4' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopy of photograph--ca. 1927 (2 1/4 X 2 1/4' negative) DETAIL SHOWING ADAPTATION THAT ALLOWED USE OF UPPER END OF ORIGINAL FLUME AND LOWER END JUST RECONSTRUCTED - Power Flume No. 1, Tacoma, La Plata County, CO

  9. Cancer near the Three Mile Island nuclear plant: radiation emissions.

    PubMed

    Hatch, M C; Beyea, J; Nieves, J W; Susser, M

    1990-09-01

    As a public charge, cancers among the 159,684 residents living within a 10-mile (16-km) radius of the Three Mile Island nuclear plant were studied relative to releases of radiation during the March 28, 1979, accident as well as to routine plant emissions. The principal cancers considered were leukemia and childhood malignancies. Estimates of the emissions delivered to small geographic study tracts were derived from mathematical dispersion models which accounted for modifying factors such as wind and terrain; the model of accident emissions was validated by readings from off-site dosimeters. Incident cancers among area residents for the period 1975-1985 (n = 5,493) were identified by a review of the records at all local and regional hospitals; preaccident and postaccident trends in cancer rates were examined. For accident emissions, the authors failed to find definite effects of exposure on the cancer types and population subgroups thought to be most susceptible to radiation. No associations were seen for leukemia in adults or for childhood cancers as a group. For leukemia in children, the odds ratio was raised, but cases were few (n = 4), and the estimate was highly variable. Moreover, rates of childhood leukemia in the Three Mile Island area are low compared with national and regional rates. For exposure to routine emissions, the odds ratios were raised for childhood cancers as a whole and for childhood leukemia, but confidence intervals were wide and included 1.0. For leukemia in adults, there was a negative trend. Trends for two types of cancer ran counter to expectation. Non-Hodgkin's lymphoma showed raised risks relative to both accident and routine emissions; lung cancer (adjusted only indirectly for smoking) showed raised risks relative to accident emissions, routine emissions, and background gamma radiation. Overall, the pattern of results does not provide convincing evidence that radiation releases from the Three Mile Island nuclear facility influenced

  10. Utilization of medical care following the Three Mile Island crisis.

    PubMed

    Houts, P S; Hu, T W; Henderson, R A; Cleary, P D; Tokuhata, G

    1984-02-01

    Four studies are reported on how utilization of primary health care was affected by the Three Mile Island (TMI) crisis and subsequent distress experienced by persons living in the vicinity of the plant. The studies concerned: 1) Blue Cross-Blue Shield records of claims by primary care physicians in the vicinity of TMI; 2) utilization rates in a family practice located near the facility; 3) interviews with persons living within five miles of TMI following the crisis; and 4) responses to a questionnaire by primary care physicians practicing within 25 miles of TMI. All four studies indicated only slight increases in utilization rates during the year following the crisis. One study found that persons who were upset during the crisis tended to be high practice utilizers both before and after the crisis. These results suggest that, while patterns of physician utilization prior to the TMI crisis predicted emotional response during the crisis, the impact of the TMI crisis on subsequent physician utilization was small.

  11. SAS 3 observations of GX 1 + 4

    NASA Technical Reports Server (NTRS)

    Doty, J. P.; Lewin, W. H. G.; Hoffman, J. A.

    1981-01-01

    GX 1 + 4 is one of the brightest celestial sources of high-energy X-rays. It is a pulsar with a period of approximately 2 min (perhaps a multiple of 2 min), decreasing at a variable rate which, since 1971, has averaged approximately 2% per year, but which can be larger than 5% per year. This is the largest rate of decrease observed for any pulsar. The rate of decrease appears to be correlated with the luminosity, in support of the idea that the period decrease is produced by accretion torques acting upon a neutron star. No evidence is seen for a Doppler shift due to motion of the pulsar in a binary orbit; this is consistent with the results of optical observations which suggest that any orbital period is fairly long (months to years). The spectrum of GX 1 + 4 is measured as a function of pulse phase, as well as the phase-averaged total spectrum, and the average spectrum of the pulses alone. The shape of the average pulsed spectrum suggests that the pulsations may be produced by 'hot spots' which are a few hundred meters in extent, with temperatures of approximately 10 to the 8th K (kT being approximately equal to 8 keV).

  12. A resolution recognizing the 100th anniversary of the Indianapolis 500 Mile Race.

    THOMAS, 112th Congress

    Sen. Lugar, Richard G. [R-IN

    2011-05-18

    05/18/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S3116; text as passed Senate: CR S3116; text of measure as introduced: CR S3113) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  13. 78 FR 49553 - Three Mile Island, Unit 2; Post Shutdown Decommissioning Activities Report

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Three Mile Island, Unit 2; Post Shutdown Decommissioning Activities Report AGENCY: Nuclear...) for Three Mile Island, Unit 2 (TMI-2). The PSDAR provides an overview of GPUN's...

  14. The last mile: earthquake risk mitigation assistance in developing countries.

    PubMed

    Shah, Haresh C

    2006-08-15

    Over the past few decades, we have seen many joint programmes between developed countries and developing countries to help the latter in managing their earthquake risks. These programmes span the whole spectrum of disciplines from seismology and geology to engineering, social science and economics. Many of these programmes have been effective in raising awareness, in urging governments to work towards risk reduction and in spawning an 'industry' of disaster management in many of the developing countries. However, even as these efforts proceed, we have seen death and destruction due to earthquake after earthquake in developing countries, strongly suggesting that the problems for which those assistance programmes were developed are not so effective. Therefore, it is natural to ask why this is happening. Are the assistance programmes reaching the right people? Maybe we are reaching the right people and doing the right type of things in these countries, but we have not allowed enough time for our actions to take effect. Maybe we are reaching the right people and doing the right actions for most of the miles we need to cover in helping communities mitigate their earthquake risks. However, the issue could be whether we are reaching people who represent the 'last mile' on this pathway. Here, I explore whether the work that many organizations and countries have done towards earthquake risk reduction over the past few decades in developing countries is appropriate or not. Why do we keep seeing the catastrophes of Sumatra, Chi Chi, Bhuj, Turkey, Algeria and on and on? I will articulate what I think is the problem. My contribution is intended to generate discussions, self-analysis of our approaches, what we are doing right and what we are not doing right. Hopefully such discussions will result in a better connection between the last mile and programmes around the world which are working towards earthquake risk mitigation.

  15. Surveying the earth from 20,000 miles

    USGS Publications Warehouse

    Colvocoresses, A.P.

    1970-01-01

    Current space programs aimed at monitoring the earth's resources concentrate on the lower orbital altitudes of 100 to 500 nautical miles. An earth synchronous (geo-stationary) orbit is 19,400 n. mi. above the earth. A powerful telephoto camera at such a location can monitor and record many time-variant phenomena far more effectively than instruments at lower altitudes. The geo-stationary systems characteristics and problem areas related to optics and telemetry are outlined and detailed, and on-going programs are discussed as they relate to the geo-stationary system.

  16. Analysis of Three Mile Island-Unit 2 accident

    SciTech Connect

    Not Available

    1980-03-01

    The Nuclear Safety Analysis Center (NSAC) of the Electric Power Research Institute has analyzed the Three Mile Island-2 accident. Early results of this analysis were a brief narrative summary, issued in mid-May 1979 and an initial version of this report issued later in 1979 as noted in the Foreword. The present report is a revised version of the 1979 report, containing summaries, a highly detailed sequence of events, a comparison of that sequence of events with those from other sources, 25 appendices, references and a list of abbreviations and acronyms. A matrix of equipment and system actions is included as a folded insert.

  17. 40 CFR 81.170 - Miles City Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Miles City Intrastate Air Quality Control Region. 81.170 Section 81.170 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.170 Miles City Intrastate Air Quality Control Region. The Miles...

  18. 33 CFR 165.554 - Security Zone; Three Mile Island Generating Station, Susquehanna River, Dauphin County...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Security Zone; Three Mile Island... Areas Fifth Coast Guard District § 165.554 Security Zone; Three Mile Island Generating Station... waters of the Susquehanna River in the vicinity of the Three Mile Island Generating Station bounded by...

  19. 33 CFR 165.554 - Security Zone; Three Mile Island Generating Station, Susquehanna River, Dauphin County...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Security Zone; Three Mile Island... Areas Fifth Coast Guard District § 165.554 Security Zone; Three Mile Island Generating Station... waters of the Susquehanna River in the vicinity of the Three Mile Island Generating Station bounded by...

  20. 33 CFR 165.554 - Security Zone; Three Mile Island Generating Station, Susquehanna River, Dauphin County...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Security Zone; Three Mile Island... Areas Fifth Coast Guard District § 165.554 Security Zone; Three Mile Island Generating Station... waters of the Susquehanna River in the vicinity of the Three Mile Island Generating Station bounded by...

  1. 33 CFR 165.554 - Security Zone; Three Mile Island Generating Station, Susquehanna River, Dauphin County...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone; Three Mile Island... Areas Fifth Coast Guard District § 165.554 Security Zone; Three Mile Island Generating Station... waters of the Susquehanna River in the vicinity of the Three Mile Island Generating Station bounded by...

  2. 33 CFR 165.554 - Security Zone; Three Mile Island Generating Station, Susquehanna River, Dauphin County...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Security Zone; Three Mile Island... Areas Fifth Coast Guard District § 165.554 Security Zone; Three Mile Island Generating Station... waters of the Susquehanna River in the vicinity of the Three Mile Island Generating Station bounded by...

  3. 76 FR 7703 - 1,4-Benzenedicarboxylic Acid, Dimethyl Ester, Polymer With 1,4-Butanediol, Adipic Acid, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... AGENCY 40 CFR Part 180 1,4-Benzenedicarboxylic Acid, Dimethyl Ester, Polymer With 1,4- Butanediol, Adipic..., polymer with 1,4-butanediol, adipic acid, and hexamethylene diisocyanate (CAS Reg. No. 55231-08-8... residues of 1,4-benzenedicarboxylic acid, dimethyl ester, polymer with 1,4-butanediol, adipic acid,...

  4. Vegetation survey of Pen Branch and Four Mile Creek wetlands

    SciTech Connect

    Not Available

    1992-10-01

    One hundred-fifty plots were recently sampled (vegetational sampling study) at the Savannah River Site (SRS). An extensive characterization of the vascular flora, in four predetermined strata (overstory, Understory, shrub layer, and ground cover), was undertaken to determine dominance, co-dominance, and the importance value (I.V.) of each species. These results will be used by the Savannah River Laboratory (SRL) to evaluate the environmental status of Four Mile Creek, Pen Branch, and two upland pine stands. Objectives of this study were to: Describe in detail the plant communities previously mapped with reference to the topography and drainage, including species of plants present: Examine the successional trends within each sampling area and describe the extent to which current vegetation communities have resulted from specific earlier vegetation disturbances (e.g., logging and grazing); describe in detail the botanical field techniques used to sample the flora; describe the habitat and location of protected and/or rare species of plants; and collect and prepare plant species as herbarium quality specimens. Sampling was conducted at Four Mile Creek and Pen Branch, and in two upland pine plantations of different age growth.

  5. Vegetation survey of Pen Branch and Four Mile Creek wetlands

    SciTech Connect

    Not Available

    1992-01-01

    One hundred-fifty plots were recently sampled (vegetational sampling study) at the Savannah River Site (SRS). An extensive characterization of the vascular flora, in four predetermined strata (overstory, Understory, shrub layer, and ground cover), was undertaken to determine dominance, co-dominance, and the importance value (I.V.) of each species. These results will be used by the Savannah River Laboratory (SRL) to evaluate the environmental status of Four Mile Creek, Pen Branch, and two upland pine stands. Objectives of this study were to: Describe in detail the plant communities previously mapped with reference to the topography and drainage, including species of plants present: Examine the successional trends within each sampling area and describe the extent to which current vegetation communities have resulted from specific earlier vegetation disturbances (e.g., logging and grazing); describe in detail the botanical field techniques used to sample the flora; describe the habitat and location of protected and/or rare species of plants; and collect and prepare plant species as herbarium quality specimens. Sampling was conducted at Four Mile Creek and Pen Branch, and in two upland pine plantations of different age growth.

  6. Runners in their forties dominate ultra-marathons from 50 to 3,100 miles

    PubMed Central

    Zingg, Matthias Alexander; Rüst, Christoph Alexander; Rosemann, Thomas; Lepers, Romuald; Knechtle, Beat

    2014-01-01

    OBJECTIVES: This study investigated performance trends and the age of peak running speed in ultra-marathons from 50 to 3,100 miles. METHODS: The running speed and age of the fastest competitors in 50-, 100-, 200-, 1,000- and 3,100-mile events held worldwide from 1971 to 2012 were analyzed using single- and multi-level regression analyses. RESULTS: The number of events and competitors increased exponentially in 50- and 100-mile events. For the annual fastest runners, women improved in 50-mile events, but not men. In 100-mile events, both women and men improved their performance. In 1,000-mile events, men became slower. For the annual top ten runners, women improved in 50- and 100-mile events, whereas the performance of men remained unchanged in 50- and 3,100-mile events but improved in 100-mile events. The age of the annual fastest runners was approximately 35 years for both women and men in 50-mile events and approximately 35 years for women in 100-mile events. For men, the age of the annual fastest runners in 100-mile events was higher at 38 years. For the annual fastest runners of 1,000-mile events, the women were approximately 43 years of age, whereas for men, the age increased to 48 years of age. For the annual fastest runners of 3,100-mile events, the age in women decreased to 35 years and was approximately 39 years in men. CONCLUSION: The running speed of the fastest competitors increased for both women and men in 100-mile events but only for women in 50-mile events. The age of peak running speed increased in men with increasing race distance to approximately 45 years in 1,000-mile events, whereas it decreased to approximately 39 years in 3,100-mile events. In women, the upper age of peak running speed increased to approximately 51 years in 3,100-mile events. PMID:24626948

  7. Tourist visitation impacts of the accident at Three Mile Island

    SciTech Connect

    Himmelberger, J.J.; Ogneva-Himmelberger, Y.A.; Baughman, M.L.

    1993-12-31

    This paper analyzes tourist visitation impacts of the March 27, 1979 accident at Three Mile Island. A review of the literature, supplemented with recollections from Pennsylvanian public officials, are used to specify a conventional tourism impact model which holds that depressed 1979 summer tourism season was more influenced by gasoline shortages and possibly other confounding variables (such as rainy local weather conditions and a polio outbreak) than by the nuclear accident. Regression analysis using monthly visitation data for Hershey Chocolate World, Gettysburg National Park, The Pennsylvania Dutch Convention and Visitor Bureau, and several state parks as dependent variables provide support for this model. Potential tourism implications of an accident at Yucca Mountain are briefly discussed in light of our findings.

  8. Adrenal cortical response to stress at Three Mile Island.

    PubMed

    Schaeffer, M A; Baum, A

    1984-01-01

    The present study examined the relationship between biochemical, psychologic, and behavioral components of chronic stress associated with living near the damaged nuclear power plant at Three Mile Island (TMI). Relative to control subjects, TMI subjects had higher levels of urinary cortisol, which correlated significantly with urinary catecholamines, self-report of physical and mental symptoms, and decrements in task performance. Further, it was found that males had higher urinary cortisol levels than females at TMI, while at the control sites, levels of cortisol were comparable between males and females. Finally, no significant relationship between coping style and urinary cortisol was detected. Levels of stress response among TMI are residents, though significantly greater than control subjects, were within normal ranges and thus should be considered subclinical in intensity. Their persistence over 17 months, however, suggests some cause for concern.

  9. Scheduling logic for Miles-In-Trail traffic management

    NASA Technical Reports Server (NTRS)

    Synnestvedt, Robert G.; Swenson, Harry; Erzberger, Heinz

    1995-01-01

    This paper presents an algorithm which can be used for scheduling arrival air traffic in an Air Route Traffic Control Center (ARTCC or Center) entering a Terminal Radar Approach Control (TRACON) Facility . The algorithm aids a Traffic Management Coordinator (TMC) in deciding how to restrict traffic while the traffic expected to arrive in the TRACON exceeds the TRACON capacity. The restrictions employed fall under the category of Miles-in-Trail, one of two principal traffic separation techniques used in scheduling arrival traffic . The algorithm calculates aircraft separations for each stream of aircraft destined to the TRACON. The calculations depend upon TRACON characteristics, TMC preferences, and other parameters adapted to the specific needs of scheduling traffic in a Center. Some preliminary results of traffic simulations scheduled by this algorithm are presented, and conclusions are drawn as to the effectiveness of using this algorithm in different traffic scenarios.

  10. Monitoring krypton-85 during Three Mile Island Unit 2 purging

    SciTech Connect

    Jester, W.A.; Baratta, A.J.

    1982-03-01

    The Penn State noble gas monitor played an important role in measuring environmental levels of /sup 85/Kr during the purging of the Three Mile Island Unit 2 primary containment. It filled a gap in the U.S. Environmental Protection Agency monitoring program, which existed between their real time monitors and their cryogenic gas chromatographic separation technique. During the 15-day purging period, the system analyzed a total of 124 samples, of which 37 were quantified to contain /sup 85/Kr in concentrations ranging from 3 X 10/sup 4/ to 1.5 X 10/sup 6/ pCi/m/sup 3/. The maximum whole body beta dose rate was found to be 0.28 mrem/h.

  11. Effects of static stretching on 1-mile uphill run performance.

    PubMed

    Lowery, Ryan P; Joy, Jordan M; Brown, Lee E; Oliveira de Souza, Eduardo; Wistocki, David R; Davis, Gregory S; Naimo, Marshall A; Zito, Gina A; Wilson, Jacob M

    2014-01-01

    It is previously demonstrated that static stretching was associated with a decrease in running economy and distance run during a 30-minute time trial in trained runners. Recently, the detrimental effects of static stretching on economy were found to be limited to the first few minutes of an endurance bout. However, economy remains to be studied for its direct effects on performance during shorter endurance events. The aim of this study was to investigate the effects of static stretching on 1-mile uphill run performance, electromyography (EMG), ground contact time (GCT), and flexibility. Ten trained male distance runners aged 24 ± 5 years with an average VO2max of 64.9 ± 6.5 mL·kg-1·min-1 were recruited. Subjects reported to the laboratory on 3 separate days interspersed by 72 hours. On day 1, anthropometrics and V[Combining Dot Above]O2max were determined on a motor-driven treadmill. On days 2 and 3, subjects performed a 5-minute treadmill warm-up and either performed a series of 6 lower-body stretches for three 30-second repetitions or sat still for 10 minutes. Time to complete a 1-mile run under stretching and nonstretching conditions took place in randomized order. For the performance run, subjects were instructed to run as fast as possible at a set incline of 5% until a distance of 1 mile was completed. Flexibility from the sit and reach test, EMG, GCT, and performance, determined by time to complete the 1-mile run, were recorded after each condition. Time to complete the run was significantly less (6:51 ± 0:28 minutes) in the nonstretching condition as compared with the stretching condition (7:04 ± 0:32 minutes). A significant condition-by-time interaction for muscle activation existed, with no change in the nonstretching condition (pre 91.3 ± 11.6 mV to post 92.2 ± 12.9 mV) but increased in the stretching condition (pre 91.0 ± 11.6 mV to post 105.3 ± 12.9 mV). A significant condition-by-time interaction for GCT was also present, with no changes in

  12. Crisis contained: the Department of Energy at Three Mile Island

    SciTech Connect

    Cantelon, P.L.; Williams, R.C.

    1982-01-01

    As historians chronicling DOE history during the Three Mile Island crisis, the authors explore what was expected to happen in the event of a nuclear accident, whether those events actually happened, and whether those involved were aware of the Interagency Radiological Assistance Plan. They contend that the serious extent of the accident was caused by human error: loss of control of the technology and confusing explanations. Relying primarily on unpublished archival materials, oral interviews with participants, and government agency reports, the authors relate the responses of scientists and politicians to a highly technical event under the public eye. The perceived danger caused and continues to cause profound psychological and political disturbances, although the danger was never real. The book concludes with a roster of participants and a chronology of events. 299 references, 23 figures.

  13. Nuclear reactor safety research since Three Mile Island

    SciTech Connect

    Mynatt, F.R.

    1982-04-09

    The Three Mile Island nuclear power plant accident has resulted in redirection of reactor safety research priorities. The small release to the environment of radioactive iodine-13 to 17 curies in a total radioactivity release of 2.4 million to 13 million curies-has led to a new emphasis on the physical chemistry of fission product behavior in accidents; the fact that the nuclear core was severely damaged but did not melt down has opened a new accident regime-that of the degraded core; the role of the operators in the progression and severity of the accident has shifted emphasis from equipment reliability to human reliability. As research progresses in these areas, the technical base for regulation and risk analysis will change substantially.

  14. Nuclear reactor safety research since three mile island.

    PubMed

    Mynatt, F R

    1982-04-09

    The Three Mile Island nuclear power plant accident has resulted in redirection of reactor safety research priorities. The small release to the environment of radioactive iodine-13 to 17 curies in a total radioactivity release of 2.4 million to 13 million curies-has led to a new emphasis on the physical chemistry of fission product behavior in accidents; the fact that the nuclear core was severely damaged but did not melt down has opened a new accident regime-that of the degraded core; the role of the operators in the progression and severity of the accident has shifted emphasis from equipment reliability to human reliability. As research progresses in these areas, the technical base for regulation and risk analysis will change substantially.

  15. 7000 miles and 7 days from the battlefield.

    PubMed

    McNeill, Margaret M

    2010-01-01

    Critically injured combat casualties are rapidly evacuated from the battlefield, and within hours of their injuries they begin a 7000-mile journey home, often arriving in the United States within 7 days. National Naval Medical Center in Bethesda, Maryland, is a major facility for wounded warrior care in the Military Health System. Throughout the facility, the staff from a variety of disciplines and all military services provides care for military personnel with injuries and illnesses, with the goal of optimizing recovery and quality of life. The foundational evidence for select aspects of this care is discussed. Innovations in training and care delivery include the Air Force Nurse Corps' Critical Care Fellowship, the new inpatient Traumatic Brain Injury Unit, and the National Intrepid Center for Excellence for Traumatic Brain Injury and Psychological Health. The future of the Medical Center includes a new name, expanded staff, and newly constructed space by Department of Defense Base Realignment and Closure activities.

  16. The geology of Six Mile Reef, eastern Long Island Sound

    USGS Publications Warehouse

    Poppe, L.J.; Denny, J.F.; Williams, S.J.; Moser, M.S.; Forfinski, N.A.; Stewart, H.F.; Doran, E.F.

    2007-01-01

    Digital terrain models, which can be produced from multibeam bathymetric data, are ordered arrays of depths for a number of sea-floor positions sampled at regularly spaced intervals. These models provide valuable base maps for marine geological interpretations that help define the variability of the sea floor (one of the primary controls of benthic habitat diversity), improve our understanding of the processes that control the distribution and transport of bottom sediments and the distribution of benthic habitats, and provide a detailed framework to guide and assist future research, monitoring, and management activities. The bathymetry interpreted herein was processed from data collected by National Oceanic and Atmospheric Administration vessels during hydrographic surveys H11361 and H11252. These surveys mapped roughly 156 km² of sea floor in the vicinity of Six Mile Reef, an area of eastern Long Island Sound where the sea floor is characterized by fields of large sand waves and an east-west decreasing gradient of bottom tidal-current speeds (fig. 1). Interpretations of the bathymetry are supplemented by concurrently collected seismic reflection data, as well as archived historic seismic profiles, sediment samples and bottom photography collected as part of a long-standing geologic mapping partnership between the State of Connecticut and the U.S. Geological Survey (fig. 2). The purpose of this digital report is 1) to provide the acoustic data layers produced during the above mentioned surveys, 2) to use them to describe the sea-floor character and bedform morphologies near Six Mile Reef, and 3) to relate these descriptions to ongoing processes and sedimentary environments.

  17. Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold.

    PubMed

    Zhang, Wenwen; Yang, Xiaobao; Chen, Weidong; Xu, Xiaoyong; Li, Lu; Zhai, Hongbin; Li, Zhong

    2010-03-10

    Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance pi-pi stacking. The synthesized compounds were identified by (1)H NMR, (13)C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid ( Aphis craccivora ).

  18. Rural and urban traffic fatalities, vehicle miles, and population density.

    PubMed

    Clark, David E; Cushing, Brad M

    2004-11-01

    The purpose of this study was to evaluate the effect of population density on the rates of motor vehicle mortality in rural and urban areas, while controlling for vehicle miles traveled (VMT). Rural and urban data for traffic mortality, VMT, and population were obtained for each state from the Federal Highway Administration for 1998-2000. Linear regression was used to estimate the effect of population density, VMT per capita, southern location, and presence of a trauma system on mortality. Variation in rural mortality rate (per 100,000 population) was proportional to rural VMT per capita, but population density and southern location were also independent predictors, together accounting for 91% of this variation. Variation in urban mortality rates was not affected by population density, but urban rates were also higher in the south. The exposure-based rural mortality rate (deaths per 100 million VMT) was inversely proportional to population density, which along with southern location explained 41% of the variation from state to state. The presence of a state trauma system did not measurably affect mortality. After controlling for VMT and southern location, state population density was a moderately strong predictor of rural but not urban traffic mortality rates.

  19. The 'last mile' of data handling: Fermilab's IFDH tools

    SciTech Connect

    Lyon, Adam L.; Mengel, Marc W.

    2014-01-01

    IFDH (Intensity Frontier Data Handling), is a suite of tools for data movement tasks for Fermilab experiments and is an important part of the FIFE[2] (Fabric for Intensity Frontier [1] Experiments) initiative described at this conference. IFDH encompasses moving input data from caches or storage elements to compute nodes (the 'last mile' of data movement) and moving output data potentially to those caches as part of the journey back to the user. IFDH also involves throttling and locking to ensure that large numbers of jobs do not cause data movement bottlenecks. IFDH is realized as an easy to use layer that users call in their job scripts (e.g. 'ifdh cp'), hiding the low level data movement tools. One advantage of this layer is that the underlying low level tools can be selected or changed without the need for the user to alter their scripts. Logging and performance monitoring can also be added easily. This system will be presented in detail as well as its impact on the ease of data handling at Fermilab experiments.

  20. Drop tests of the Three Mile Island knockout canister

    SciTech Connect

    Box, W.D.; Aaron, W.S.; Shappert, L.B.; Childress, P.C.; Quinn, G.J.; Smith, J.V.

    1986-09-01

    A type of Three Mile Island Unit 2 (TMI-2) defueling canister, called a ''knockout'' canister, was subjected to a series of drop tests at the Oak Ridge National Laboratory's Drop Test Facility. These tests were designed to confirm the structural integrity of internal fixed neutron poisons in support of a request for NRC licensing of this type of canister for the shipment of TMI-2 reactor fuel debris to the Idaho National Engineering Laboratory (INEL) for the Core Examination R and D Program. Work conducted at the Oak Ridge National Laboratory included (1) precise physical measurements of the internal poison rod configuration before assembly, (2) canister assembly and welding, (3) nondestructive examination (an initial hydrostatic pressure test and an x-ray profile of the internals before and after each drop test), (4) addition of a simulated fuel load, (5) instrumentation of the canister for each drop test, (6) fabrication of a cask simulation vessel with a developed and tested foam impact limiter, (7) use of refrigeration facilities to cool the canister to well below freezing prior to three of the drops, (8) recording the drop test with still, high-speed, and normal-speed photography, (9) recording the accelerometer measurements during impact, (10) disassembly and post-test examination with precise physical measurements, and (11) preparation of the final report.

  1. Tribulations of the Last Mile: Sides from a Regional Program

    PubMed Central

    Del Rio Vilas, Victor J.; Freire de Carvalho, Mary J.; Vigilato, Marco A. N.; Rocha, Felipe; Vokaty, Alexandra; Pompei, Julio A.; Molina Flores, Baldomero; Fenelon, Natael; Cosivi, Ottorino

    2017-01-01

    In Latin American and Caribbean (LAC) countries, the number of cases of dog-mediated human rabies is at its lowest since the onset of the Regional Program for Rabies Elimination in 1983, a commitment from LAC countries to eliminate dog-mediated rabies coordinated by the Pan American Health Organization. Despite minor setbacks, the decline in the number of human cases has been constant since 1983. While many LAC countries have significantly reduced rabies to a level where it is no longer significant public health concern, elimination has proven elusive and pockets of the disease remain across the region. In the 33-year period since 1983, the region has set and committed to four dates for elimination (1990, 2000, 2012, and 2015). In this paper, we ponder on the multiple causes behind the elusive goal of rabies elimination, such as blanket regional goals oblivious to the large heterogeneity in national rabies capacities. Looking ahead to the elimination of dog-mediated rabies in the region, now established for 2022, we also review the many challenges and questions that the region faces in the last mile of the epidemic. Given the advanced position of the Americas in the race toward elimination, our considerations could provide valuable knowledge to other regions pursuing elimination goals. PMID:28197407

  2. Underwater plasma arc cutting in Three Mile Island's reactor

    SciTech Connect

    McGough, M.S.; Knetl, G.J. ); Austin, W.E. )

    1989-07-01

    On March 28, 1979, the Pennsylvania Three Mile Island nuclear power plant Unit 2 (TMI-2) suffered a partial fuel-melt accident. During this accident, over 20,000 lb of molten fuel flowed through holes melted through the baffle plates and through the lower-core support assembly (LCSA). The molten fuel subsequently resolidified in the bottom of the reactor vessel. The lower-core support assembly of the TMI-2 reactor was not structurally damaged during the accident. In order to permit defueling of that region of the core, the LCSA was cut to permit access. A five-axis teleoperator was developed to deliver plasma arc cutting, rotary grinding and abrasive waterjet cutting of end effectors to the LCSA. Complex geometry sectioning was completed in a mock-up facility at chemistry and pressure conditions simulating those of the vessel, prior to actual in-vessel operations. In-vessel activities began in early May 1988 and were completed on April 11, 1989. This paper presents the details of the in-vessel cutting efforts.

  3. Vegetation survey of Four Mile Creek wetlands. [Savannah River Plant

    SciTech Connect

    Loehle, C.

    1990-11-01

    A survey of forested wetlands along upper Four Mile Creek was conducted. The region from Road 3 to the creek headwaters was sampled to evaluate the composition of woody and herbaceons plant communities. All sites were found to fall into either the Nyssa sylvatica (Black Gum) -- Persea borbonia (Red Bay) or Nyssa sylvatica -- Acer rubrum (Red Maple) types. These community types are generally species-rich and diverse. Previous studies (Greenwood et al., 1990; Mackey, 1988) demonstrated contaminant stress in areas downslope from the F- and H-Area seepage basins. In the present study there were some indications of contaminant stress. In the wetland near H-Area, shrub basal area, ground cover stratum species richness, and diversity were low. In the area surrounding the F-Area tree kill zone, ground cover stratum cover and shrub basal area were low and ground cover stratum species richness was low. The moderately stressed site at F-Area also showed reduced overstory richness and diversity and reduced ground cover stratum richness. These results could, however, be due to the very high basal area of overstory trees in both stressed F-Area sites that would reduce light availability to understory plants. No threatened or endangered plant species were found in the areas sampled. 40 refs., 4 figs., 8 tabs.

  4. Four Mile Creek bottomland restoration program. Final report

    SciTech Connect

    McLeod, K.W.

    1995-12-31

    On the Savannah River Site (SRS), nuclear production reactors were cooled by a once-through cooling cycle, using water from the Savannah River and discharging the effluent to small tributaries of the Savannah River. Four Mile Creek (also known as Fourmile Branch) is a third order tributary of the Savannah River on the upper coastal plain of South Carolina. It received thermal effluent from C Reactor from 1955 to 1985, which increased the flow rate, water depth and water temperature. Prior to 1955, the base flow was approximately one cubic meter per second, but increased, with the reactor effluent, to approximately 11 cubic meters per second, raising the water depth in the channel by 15 to 30 cm. Effluent temperature at the outfall was approximately 60 C and at the delta was 40 to 45 C, depending on the operation level of the reactor, the season of the year and the specific meteorological conditions. The increased flow rate also increased erosion in the upper reaches of the stream with deposition of this eroded material occurring in the delta averaging 60 cm of newly deposited sand on top of the former substrate.

  5. Tribulations of the Last Mile: Sides from a Regional Program.

    PubMed

    Del Rio Vilas, Victor J; Freire de Carvalho, Mary J; Vigilato, Marco A N; Rocha, Felipe; Vokaty, Alexandra; Pompei, Julio A; Molina Flores, Baldomero; Fenelon, Natael; Cosivi, Ottorino

    2017-01-01

    In Latin American and Caribbean (LAC) countries, the number of cases of dog-mediated human rabies is at its lowest since the onset of the Regional Program for Rabies Elimination in 1983, a commitment from LAC countries to eliminate dog-mediated rabies coordinated by the Pan American Health Organization. Despite minor setbacks, the decline in the number of human cases has been constant since 1983. While many LAC countries have significantly reduced rabies to a level where it is no longer significant public health concern, elimination has proven elusive and pockets of the disease remain across the region. In the 33-year period since 1983, the region has set and committed to four dates for elimination (1990, 2000, 2012, and 2015). In this paper, we ponder on the multiple causes behind the elusive goal of rabies elimination, such as blanket regional goals oblivious to the large heterogeneity in national rabies capacities. Looking ahead to the elimination of dog-mediated rabies in the region, now established for 2022, we also review the many challenges and questions that the region faces in the last mile of the epidemic. Given the advanced position of the Americas in the race toward elimination, our considerations could provide valuable knowledge to other regions pursuing elimination goals.

  6. A versatile approach to N-alkylated 1,4-dideoxy-1,4-imino-D-arabinitols and 1,4-dideoxy-1,4-imino-L-xylitols.

    PubMed

    Wang, Guan-Nan; Yang, Lin; Zhang, Li-He; Ye, Xin-Shan

    2011-04-01

    A versatile and concise synthesis of N-alkylated 1,4-dideoxy-1,4-imino-D-arabinitol and 1,4-dideoxy-1,4-imino-L-xylitol derivatives is described. These were prepared using pseudohemiketal lactams as key intermediates, which in turn were obtained from sucrose. The key intermediates were prepared by a diastereospecific tandem reaction which facilitated the introduction of various substituents on the nitrogen atom of the iminosugars.

  7. 7 CFR 1.4 - Public access to certain materials.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Public access to certain materials. 1.4 Section 1.4 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.4 Public access to certain materials. (a) In accordance with 5 U.S.C. 552(a)(2), each agency within the...

  8. 26 CFR 303.1-4 - Computation of taxes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Computation of taxes. 303.1-4 Section 303.1-4... ADMINISTRATION TAXES UNDER THE TRADING WITH THE ENEMY ACT § 303.1-4 Computation of taxes. (a) Detail of employees... computation of tax liability under this part, except as otherwise provided in this part, the vesting...

  9. 47 CFR 1.4 - Computation of time.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Computation of time. 1.4 Section 1.4 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure General § 1.4 Computation of time. (a) Purpose. The purpose of this rule section is to detail the method for computing the amount of...

  10. IRIS Toxicological Review of 1,4-Dioxane (Final Report)

    EPA Science Inventory

    The final Toxicological Review of 1,4-dioxane provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to 1,4-dioxane. Human health risk concerns for 1,4-dioxane are primarily related to exposure from drinking, ground, ...

  11. 5 CFR 1.4 - Extent of the excepted service.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Extent of the excepted service. 1.4 Section 1.4 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE RULES COVERAGE AND DEFINITIONS (RULE I) § 1.4 Extent of the excepted service. (a) The excepted service shall include all...

  12. Flood-plain areas of the Mississippi River, mile 866.8 to mile 888.0, Minnesota

    USGS Publications Warehouse

    Carlson, George H.; Gue, Lowell C.

    1980-01-01

    Profiles of the regional flood, 500-year flood, and flood-protection elevation have been developed for a 21-mile reach of the Mississippi River. Areas flooded by the regional flood and by the 500-year flood were delineated by photogrammetric mapping techniques and are shown on seven large-scale map sheets. Over 1,300 acres of flood plain are included in the cities of Anoka, Champlin, Coon Rapids, Dayton, Ramsey and Elk River, and in unincorporated areas of Wright County. The flood-outline maps and flood profiles comprise data needed by local units of government to adopt, enforce, and administer flood-plain management regulations along the Mississippi River throughout the study reach. Streamflow data from two gaging stations provided the basis for definition of the regional and 500-year floods. Cross-section data obtained at 83 locations were used to develop a digital computer model of the river. Flood elevation and discharge data from the 1965 flood provided a basis for adjusting the computer model. Information relating the history of floods, formation of ice jams, and duration of flood elevations at Anoka and at Elk River are included.

  13. "Last mile" challenges to in situ volcanic data transmission

    NASA Astrophysics Data System (ADS)

    Fonseca, J. F. B. D.; Faria, B. V. E.; Trindade, J.; Cruz, G.; Chambel, A.; Silva, F. M.; Pereira, R. L.; Vazão, T.

    2013-08-01

    Scientists play a key role in volcanic risk mitigation, but rely heavily on fast access to data acquired in the vicinity of an active volcano. Hazardous volcanoes are often located in remote areas were telecommunications infrastructure is fragile. Besides being exposed directly to the volcanic hazard, the infrastructure in such remote areas can suffer also from "last mile" limitations derived from lack of market demand for data transmission services. In this paper, we report on the findings of FP7 MIAVITA project in the topic of volcanic data transmission. We draw on the contribution of partners from emergent or developing countries to identify the main bottlenecks and fragilities. We present also the results of an experiment conducted in Fogo island, Cape Verde, to test the availability of VSAT services adequate for volcanic monitoring. We warn against the false sense of security resulting from increasingly ubiquitous connectivity, and point out the lack of reliability of many consumer-type services, particularly during emergencies when such services are likely to crash due to excess of demand from the public. Finally, we propose guidelines and recommend best practices for the design of volcanic monitoring networks in what concerns data transmission. In particular, we advise that the data transmission equipment close to the exposed area should be owned, operated and maintained by the volcanic monitoring institution. We exemplify with the setup of the Fogo telemetric interface, which uses low-power licence-free radio modems to reach a robust point of entry into the public network at a suitable distance from the volcano.

  14. "Last mile" challenges to in situ volcanic data transmission

    NASA Astrophysics Data System (ADS)

    Fonseca, J. F. B. D.; Faria, B. V. E.; Trindade, J.; Cruz, G.; Chambel, A.; Silva, F. M.; Pereira, R. L.; Vazão, T.

    2013-12-01

    Scientists play a key role in volcanic risk management, but rely heavily on fast access to data acquired in the vicinity of an active volcano. Hazardous volcanoes are often located in remote areas were telecommunications infrastructure is fragile. Besides being exposed directly to the volcanic hazard, the infrastructure in such remote areas can also suffer from "last mile" limitations derived from lack of market demand for data transmission services. In this paper, we report on the findings of the FP7 MIAVITA project in the topic of volcanic data transmission. We draw on the contribution of partners from emergent or developing countries to identify the main bottlenecks and fragilities. We also present the results of an experiment conducted on Fogo Island, Cape Verde, to test the availability of VSAT services adequate for volcanic monitoring. We warn against the false sense of security resulting from increasingly ubiquitous connectivity, and point out the lack of reliability of many consumer-type services, particularly during emergencies when such services are likely to crash due to excess of demand from the public. Finally, we propose guidelines and recommend best practices for the design of volcanic monitoring networks in what concerns data transmission. In particular, we advise that the data transmission equipment close to the exposed area should be owned, operated and maintained by the volcanic monitoring institution. We exemplify with the set-up of the Fogo telemetric interface, which uses low-power licence-free radio modems to reach a robust point of entry into the public network at a suitable distance from the volcano.

  15. 40 CFR 721.990 - 1,4-Benzedicarboxylic acid, dimethyl ester, polymer with 1,4 - butanediol, cyclized.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ester, polymer with 1,4 - butanediol, cyclized. 721.990 Section 721.990 Protection of Environment..., dimethyl ester, polymer with 1,4 - butanediol, cyclized. (a) Chemical substance and significant new uses..., polymer with 1,4 - butanediol, cyclized (PMN P-00-0789; CAS No. 263244-54-8) is subject to reporting...

  16. 40 CFR 721.990 - 1,4-Benzedicarboxylic acid, dimethyl ester, polymer with 1,4 - butanediol, cyclized.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ester, polymer with 1,4 - butanediol, cyclized. 721.990 Section 721.990 Protection of Environment..., dimethyl ester, polymer with 1,4 - butanediol, cyclized. (a) Chemical substance and significant new uses..., polymer with 1,4 - butanediol, cyclized (PMN P-00-0789; CAS No. 263244-54-8) is subject to reporting...

  17. 40 CFR 721.990 - 1,4-Benzedicarboxylic acid, dimethyl ester, polymer with 1,4 - butanediol, cyclized.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ester, polymer with 1,4 - butanediol, cyclized. 721.990 Section 721.990 Protection of Environment..., dimethyl ester, polymer with 1,4 - butanediol, cyclized. (a) Chemical substance and significant new uses..., polymer with 1,4 - butanediol, cyclized (PMN P-00-0789; CAS No. 263244-54-8) is subject to reporting...

  18. 40 CFR 721.990 - 1,4-Benzedicarboxylic acid, dimethyl ester, polymer with 1,4 - butanediol, cyclized.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ester, polymer with 1,4 - butanediol, cyclized. 721.990 Section 721.990 Protection of Environment..., dimethyl ester, polymer with 1,4 - butanediol, cyclized. (a) Chemical substance and significant new uses..., polymer with 1,4 - butanediol, cyclized (PMN P-00-0789; CAS No. 263244-54-8) is subject to reporting...

  19. 40 CFR 721.990 - 1,4-Benzedicarboxylic acid, dimethyl ester, polymer with 1,4 - butanediol, cyclized.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ester, polymer with 1,4 - butanediol, cyclized. 721.990 Section 721.990 Protection of Environment..., dimethyl ester, polymer with 1,4 - butanediol, cyclized. (a) Chemical substance and significant new uses..., polymer with 1,4 - butanediol, cyclized (PMN P-00-0789; CAS No. 263244-54-8) is subject to reporting...

  20. Understanding Victims of Technological Disaster: Beliefs and Worries of Three Mile Island.

    ERIC Educational Resources Information Center

    Prince-Embury, Sandra; Rooney, James

    The primary purpose of the present study was to examine how prevalent were concerns about restarting Three Mile Island nuclear reactor Unit I among people within a five-mile radius of the plant four years after the accident involving reactor Unit II. Also explored were concerns related to expectations about the restart of Unit I, perception of…

  1. 14 CFR 97.5 - Bearings, courses, tracks, headings, radials, miles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Bearings, courses, tracks, headings, radials, miles. 97.5 Section 97.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Bearings, courses, tracks, headings, radials, miles. (a) All bearings, courses, tracks, headings,...

  2. 14 CFR 97.5 - Bearings, courses, tracks, headings, radials, miles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Bearings, courses, tracks, headings, radials, miles. 97.5 Section 97.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Bearings, courses, tracks, headings, radials, miles. (a) All bearings, courses, tracks, headings,...

  3. 14 CFR 97.5 - Bearings, courses, tracks, headings, radials, miles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Bearings, courses, tracks, headings, radials, miles. 97.5 Section 97.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Bearings, courses, tracks, headings, radials, miles. (a) All bearings, courses, tracks, headings,...

  4. 14 CFR 97.5 - Bearings, courses, tracks, headings, radials, miles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Bearings, courses, tracks, headings, radials, miles. 97.5 Section 97.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Bearings, courses, tracks, headings, radials, miles. (a) All bearings, courses, tracks, headings,...

  5. 14 CFR 97.5 - Bearings, courses, tracks, headings, radials, miles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Bearings, courses, tracks, headings, radials, miles. 97.5 Section 97.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Bearings, courses, tracks, headings, radials, miles. (a) All bearings, courses, tracks, headings,...

  6. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall receive a Class IA brake test performed by a qualified person, as defined in § 232.5, at a location...

  7. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall receive a Class IA brake test performed by a qualified person, as defined in § 232.5, at a location...

  8. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall receive a Class IA brake test performed by a qualified person, as defined in § 232.5, at a location...

  9. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall receive a Class IA brake test performed by a qualified person, as defined in § 232.5, at a location...

  10. 49 CFR 232.207 - Class IA brake tests-1,000-mile inspection.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Class IA brake tests-1,000-mile inspection. 232... Class IA brake tests—1,000-mile inspection. (a) Except as provided in § 232.213, each train shall receive a Class IA brake test performed by a qualified person, as defined in § 232.5, at a location...

  11. 76 FR 36316 - Safety Zone; Upper Mississippi River, Mile 180.0 to 179.0

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Upper Mississippi River, Mile 180.0 to 179... temporary safety zone for all waters of the Upper Mississippi River, from Mile 180.0 to 179.0, extending the... is prohibited unless specifically authorized by the Captain of the Port Upper Mississippi River or...

  12. 75 FR 41764 - Safety Zone; Mississippi River, Mile 840.0 to 839.8

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River, Mile 840.0 to 839.8... temporary safety zone for all waters of the Upper Mississippi River, Mile 840.0 to 839.8, extending the... associated with a barge based firework display occurring on the Upper Mississippi River. Entry into this...

  13. 78 FR 46258 - Safety Zone; Upper Mississippi River, Mile 662.8 to 663.9

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Upper Mississippi River, Mile 662.8 to 663... temporary safety zone for all waters of the Upper Mississippi River, from mile 662.8 to 663.9, extending the... the Upper Mississippi River. Entry into this zone is prohibited unless specifically authorized by...

  14. Variable Seed Viability of Mile-a-Minute Weed (Devil's Tearthumb, Persicaria perfoliata)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Mile-a-minute weed or devil's tearthumb is an invasive annual vine in the Mid-Atlantic and Northeastern United States. It reproduces solely through seeds, and therefore a key aspect of mile-a-minute weed biology and control concerns the production of viable seed. Our study aimed to identify how seed...

  15. 77 FR 19937 - Drawbridge Operation Regulation; Mile 21.6, Illinois Waterway, Hardin, IL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-03

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulation; Mile 21.6, Illinois Waterway, Hardin... Coast Guard has issued a temporary deviation from the operating schedule that governs the Hardin Drawbridge across the Illinois Waterway, mile 21.6, at Hardin, Illinois. The deviation is necessary...

  16. 77 FR 47525 - Safety Zone, Mississippi River, Mile Marker 291 to 295

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone, Mississippi River, Mile Marker 291 to 295... temporary safety zone for all waters of the Lower Mississippi River, extending the entire width of the river... pattern due to dredging operations in the vicinity of Tunica Bend, Lower Mississippi River Mile...

  17. 75 FR 55272 - Safety Zone; Mississippi River, Mile 212.0 to 214.5

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River, Mile 212.0 to 214.5... temporary safety zone for waters of the Upper Mississippi River, Mile 212.0 to 214.5, extending West of... display occurring on the Upper Mississippi River. Entry into this zone is prohibited unless...

  18. 75 FR 53193 - Safety Zone; Mississippi River, Mile 427.3 to 427.5

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River, Mile 427.3 to 427.5 AGENCY: Coast Guard... for all waters of the Upper Mississippi River, Mile 427.3 to 427.5, extending the entire width of the... land based firework display occurring on the Upper Mississippi River. Entry into this zone will...

  19. 76 FR 7515 - Safety Zone; Mississippi River, Mile 842.0 to 839.5

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River, Mile 842.0 to 839.5... establishing a temporary safety zone for all waters of the Upper Mississippi River, Mile 842.0 to 839.5... personnel during the swim leg of the OptumHealth Half Iron Triathlon occurring in the Upper...

  20. 49 CFR 172.523 - EXPLOSIVES 1.4 placard.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false EXPLOSIVES 1.4 placard. 172.523 Section 172.523... SECURITY PLANS Placarding § 172.523 EXPLOSIVES 1.4 placard. (a) Except for size and color, the EXPLOSIVES 1... subpart, the background color on the EXPLOSIVES 1.4 placard must be orange. The “*” shall be...

  1. 49 CFR 172.523 - EXPLOSIVES 1.4 placard.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false EXPLOSIVES 1.4 placard. 172.523 Section 172.523... SECURITY PLANS Placarding § 172.523 EXPLOSIVES 1.4 placard. (a) Except for size and color, the EXPLOSIVES 1... subpart, the background color on the EXPLOSIVES 1.4 placard must be orange. The “*” shall be...

  2. 49 CFR 172.523 - EXPLOSIVES 1.4 placard.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false EXPLOSIVES 1.4 placard. 172.523 Section 172.523... SECURITY PLANS Placarding § 172.523 EXPLOSIVES 1.4 placard. (a) Except for size and color, the EXPLOSIVES 1... subpart, the background color on the EXPLOSIVES 1.4 placard must be orange. The “*” shall be...

  3. 49 CFR 172.523 - EXPLOSIVES 1.4 placard.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false EXPLOSIVES 1.4 placard. 172.523 Section 172.523... SECURITY PLANS Placarding § 172.523 EXPLOSIVES 1.4 placard. (a) Except for size and color, the EXPLOSIVES 1... subpart, the background color on the EXPLOSIVES 1.4 placard must be orange. The “*” shall be...

  4. 49 CFR 172.523 - EXPLOSIVES 1.4 placard.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false EXPLOSIVES 1.4 placard. 172.523 Section 172.523... SECURITY PLANS Placarding § 172.523 EXPLOSIVES 1.4 placard. (a) Except for size and color, the EXPLOSIVES 1... subpart, the background color on the EXPLOSIVES 1.4 placard must be orange. The “*” shall be...

  5. 43 CFR 3425.1-4 - Emergency leasing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Emergency leasing. 3425.1-4 Section 3425.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) COMPETITIVE LEASING Leasing on Application § 3425.1-4 Emergency leasing. (a) An emergency lease sale may be held in response to an application under this...

  6. 43 CFR 3425.1-4 - Emergency leasing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Emergency leasing. 3425.1-4 Section 3425.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) COMPETITIVE LEASING Leasing on Application § 3425.1-4 Emergency leasing. (a) An emergency lease sale may be held in response to an application under this...

  7. 43 CFR 3425.1-4 - Emergency leasing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Emergency leasing. 3425.1-4 Section 3425.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) COMPETITIVE LEASING Leasing on Application § 3425.1-4 Emergency leasing. (a) An emergency lease sale may be held in response to an application under this...

  8. IRIS Toxicological Review of 1,4-Dioxane (Final Report)

    EPA Science Inventory

    EPA announced the release of the final report, Toxicological Review of 1,4-Dioxane (CAS No. 123-91-1): In Support of Summary Information on the Integrated Risk Information System (IRIS). The final Toxicological Review of 1,4-dioxane provides scientific support and rationa...

  9. Photochemistry Of 2,5-Diacyl-1, 4-Dimethylbenzenes

    NASA Technical Reports Server (NTRS)

    Meador, Michael A.

    1989-01-01

    Experiments described in report revealed potentially useful aspects of photochemistry of 2,5-dibenzoyl-1, 4-dimethylbenzene (DBX) and 2,5-diacetyl-1, 4-dimethylbenzene (DAX). Behavior of these compounds reminiscent of orthoalkylphenyl ketones, studied from similar perspective for more than two decades.

  10. First Synthesis of 1,4-Dimethoxy-2-Naphthoxyacetic acid.

    PubMed

    Chinea, Kimberly; Banerjee, Ajoy K

    2015-07-01

    2-Acetyl-1-hydroxynaphthalene was converted into 1,4-dimethoxy-2-naphthoxyacetic acid in seven steps (methylation, Bayer-Villiger oxidation, hydrolysis, bromination, methylation, alkylation and hydrolysis). 2-Hydroxy-1,4-naphthoquinone on acetylation, aromatization, methylation and hydrolysis, respectively, also yielded the title compound.

  11. 17 CFR 1.4 - Use of electronic signatures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Use of electronic signatures. 1.4 Section 1.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL... pool participant or a client of a commodity trading advisor, an electronic signature executed by...

  12. 17 CFR 1.4 - Use of electronic signatures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Use of electronic signatures. 1.4 Section 1.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL... pool participant or a client of a commodity trading advisor, an electronic signature executed by...

  13. Radiolabeling of Cramoll 1,4: Evaluation of the Biodistribution

    PubMed Central

    Ferreira de Carvalho Patricio, Beatriz; Lima-Ribeiro, Maria Helena Madruga; dos Santos Correia, Maria Tereza; dos Anjos Carneiro-Leão, Ana Maria; de Souza Albernaz, Marta; Barboza, Thiago; de Souza, Sergio Augusto Lopes; Santos-Oliveira, Ralph

    2011-01-01

    The cramoll 1,4 is a well-studied lectin. However, few studies about its biodistribution have been done before. In this study, we radiolabeled the cramol 1,4 with Tc-99m and analyzed the biodistribution. The results showed that the cramol has an abnormal uptake by the bowel with reflections on its clearance mechanism. PMID:21760823

  14. 43 CFR 3425.1-4 - Emergency leasing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Emergency leasing. 3425.1-4 Section 3425.1..., DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) COMPETITIVE LEASING Leasing on Application § 3425.1-4 Emergency leasing. (a) An emergency lease sale may be held in response to an application under this...

  15. Walter Miles, Pop Warner, B. C. Graves, and the psychology of football.

    PubMed

    Baugh, Frank G; Benjamin, Ludy T

    2006-01-01

    In 1926-1927, a graduate student, B. C. Graves, working with Stanford University psychologist Walter Miles and legendary football coach Pop Warner, conducted an investigation of variations in signal calling as they affected the charging times of football players. The study was one of two that involved Miles and the ingenious multiple chronograph that he had invented to time the reactions of seven players simultaneously. These studies represented a brief digression in the career of Miles, who certainly was no sport psychologist. They tell of an interesting collaboration between scientist and coaches that produced one of the richest studies in sport psychology in the first half of the twentieth century.

  16. Mental health effects of the Three Mile Island nuclear reactor restart

    SciTech Connect

    Dew, M.A.; Bromet, E.J.; Schulberg, H.C.; Dunn, L.O.; Parkinson, D.K.

    1987-08-01

    Controversy over potential mental health effects of the Three Mile Island Unit-1 restart led the authors to examine prospectively the pattern of psychiatric symptoms in a sample of Three Mile Island area mothers of young children. Symptom levels after restart were elevated over previous levels; a sizable subcohort of the sample reported relatively serious degrees of postrestart distress. History of diagnosable major depression and generalized anxiety following the Three Mile Island accident, plus symptoms and beliefs about personal risk prior to the restart, best predicted postrestart symptoms.

  17. World's mountains over 5 miles above sea level as seen from the Apollo 7

    NASA Technical Reports Server (NTRS)

    1968-01-01

    The world's dozen peaks which reach a height of greater than five miles above sea level are seen in this photograph from the Apollo 7 spacecraft at an altitude of 130 nautical miles. The 29,028 ft. high Mount Everest is at lower center. On the central horizon can be seen the 28,250 ft. high Mount Godwin-Austen (K-2) some 800 miles northwest of Mount Everest. In the lower right, Mount Kanchenjunga rises 28,208 ft. to separate Nepal from Sikkim. The snow line on the peaks was at 17,500 ft. In the upper right the lake-studded highlands of Tibet are visible.

  18. UV-extended E-MILES stellar population models: young components in massive early-type galaxies

    NASA Astrophysics Data System (ADS)

    Vazdekis, A.; Koleva, M.; Ricciardelli, E.; Röck, B.; Falcón-Barroso, J.

    2016-12-01

    We present UV-extended E-MILES stellar population synthesis models covering the spectral range λλ 1680-50 000 Å at moderately high resolution. We employ the NGSL space-based stellar library to compute spectra of single-age, single-metallicity stellar populations in the wavelength range from 1680 to 3540 Å. These models represent a significant improvement in resolution and age/metallicity coverage over previous studies based on earlier space-based libraries. These model spectra were joined with those we computed in the visible using MILES, and other empirical libraries for redder wavelengths. The models span the metallicity range -1.79≤ [M/H]≤ +0.26 and ages above 30 Myr, for a suite of initial mass function types with varying slopes. We focus on the behaviour of colours, spectra and line-strength indices in the UV range as a function of relevant stellar population parameters. Whereas some indices strengthen with increasing age and metallicity, as most metallicity indicators in the visible, other indices peak around 3 Gyr for metal-rich stellar populations, such as Mg at 2800 Å. Our models provide reasonably good fits to the integrated colours and most line strengths of the stellar clusters of the Milky Way and Large Magellanic Cloud. Our full spectrum fits in the UV range for a representative set of early-type galaxies (ETGs) of varying mass yield age and metallicity estimates in very good agreement with those obtained in the optical range. The comparison of UV colours and line strengths of massive ETGs with our models reveals the presence of young stellar components, with ages in the range 0.1-0.5 Gyr and mass fractions 0.1-0.5 per cent, on the top of an old stellar population.

  19. 77 FR 6013 - Moving Security Zone Around Escorted Vessels On the Lower Mississippi River Between Mile Marker...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... Lower Mississippi River Between Mile Marker 90.0 Above Head of Passes to Mile Marker 110.0 Above Head of Passes AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Captain of the Port of...

  20. Subchronic Toxicity Study on 1,4-Dithiane.

    DTIC Science & Technology

    1987-08-01

    respectively. The left-ear clipped control male in cage 14 had malocclusion (a bite defect) and was excluded from all statistical analyses. An ANOVA on the...have the nose crystals. The time required for deposition of the nose crystals is important for a risk assessment analysis for 1,4-dithiane. 3) Studying...regression of the 1,4-dithiane-induced tissue damage is essential for a risk -assessment analysis for 1,4-dithiane. 4.) Studying the strain and species

  1. NASA Green Flight Challenge: Conceptual Design Approaches and Technologies to Enable 200 Passenger Miles per Gallon

    NASA Technical Reports Server (NTRS)

    Wells, Douglas P.

    2011-01-01

    The Green Flight Challenge is one of the National Aeronautics and Space Administration s Centennial Challenges designed to push technology and make passenger aircraft more efficient. Airliners currently average around 50 passenger-miles per gallon and this competition will push teams to greater than 200 passenger-miles per gallon. The aircraft must also fly at least 100 miles per hour for 200 miles. The total prize money for this competition is $1.65 Million. The Green Flight Challenge will be run by the Comparative Aircraft Flight Efficiency (CAFE) Foundation September 25 October 1, 2011 at Charles M. Schulz Sonoma County Airport in California. Thirteen custom aircraft were developed with electric, bio-diesel, and other bio-fuel engines. The aircraft are using various technologies to improve aerodynamic, propulsion, and structural efficiency. This paper will explore the feasibility of the rule set, competitor vehicles, design approaches, and technologies used.

  2. Bureaucracy in crisis: Three Mile Island, the shuttle Challenger, and risk assessment

    SciTech Connect

    Casamayou, M.H.

    1995-07-01

    This book is a study in organizational theory about how technological bureaucracies perceive, communicate about, and respond to potential risks to public safety, using Three mile island and the Challenger accident as examples.

  3. MILES device: ocular hazard evaluation. Interim report, 1 May-30 September 1979

    SciTech Connect

    Zuclich, J.A.; Tredici, T.J.; Mikesell, G.W. Jr.; Gibbons, W.D.; Schmidt, R.E.

    1980-03-01

    This report describes an attempt to find ocular effects in the primate eye as a result of exposure to a MILES (Multiple Integrated Laser Engagement System) laser transmitter for a M16A1 rifle. The MILES device incorporates a pulsed gallium arsenide laser operating in the near infrared. For the exposure parameters reported, no ocular alterations could be detected with either a fundus camera or a direct ophthalmoscope.

  4. 75 FR 39163 - Safety Zone; Illinois River, Mile 119.7 to 120.3

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Illinois River, Mile 119.7 to 120.3 AGENCY... safety zone for ] all waters of the Illinois River, Mile 119.7 to 120.3, extending the entire width of... representative. DATES: This rule is effective from 10 a.m. on July 17 until 7 p.m. on July 18, 2010....

  5. 76 FR 32994 - Nine Mile Point 3 Nuclear Project, LLC and Unistar Nuclear Operating Services, LLC; Combined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... License Application for Nine Mile Point 3 Nuclear Power Plant; Exemption 1.0 Background Nine Mile Point 3... 52, ``Licenses, Certifications, and Approvals for Nuclear Power Plants.'' This reactor is to be identified as Nine Mile Point 3 Nuclear Power Plant (NMP3NPP), and located adjacent to the current Nine...

  6. 33 CFR 165.T08-0433 - Safety Zone; Waterway Closure, Atchafalaya River from Mile Marker 117 (Morgan City Railroad...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Atchafalaya River from Mile Marker 117 (Morgan City Railroad Bridge) to Mile Marker 0 (Simmesport, LA). 165... Safety Zone; Waterway Closure, Atchafalaya River from Mile Marker 117 (Morgan City Railroad Bridge) to... waters of the Atchafalaya River between MM 117 (Morgan City Railroad Bridge) and MM 0 (Simmesport,...

  7. 25 CFR 39.710 - How does a school calculate annual bus transportation miles for day students?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true How does a school calculate annual bus transportation... Miles § 39.710 How does a school calculate annual bus transportation miles for day students? To calculate the total annual bus transportation miles for day students, a school must use the...

  8. 25 CFR 39.710 - How does a school calculate annual bus transportation miles for day students?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How does a school calculate annual bus transportation... Miles § 39.710 How does a school calculate annual bus transportation miles for day students? To calculate the total annual bus transportation miles for day students, a school must use the...

  9. 25 CFR 39.710 - How does a school calculate annual bus transportation miles for day students?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How does a school calculate annual bus transportation... Miles § 39.710 How does a school calculate annual bus transportation miles for day students? To calculate the total annual bus transportation miles for day students, a school must use the...

  10. 25 CFR 39.710 - How does a school calculate annual bus transportation miles for day students?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How does a school calculate annual bus transportation... Miles § 39.710 How does a school calculate annual bus transportation miles for day students? To calculate the total annual bus transportation miles for day students, a school must use the...

  11. 25 CFR 39.710 - How does a school calculate annual bus transportation miles for day students?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How does a school calculate annual bus transportation... Miles § 39.710 How does a school calculate annual bus transportation miles for day students? To calculate the total annual bus transportation miles for day students, a school must use the...

  12. 77 FR 29254 - Safety Zones, Large Cruise Ships; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-17

    ... River, Southwest Pass Sea Buoy to Mile Marker 96.0; New Orleans, LA AGENCY: Coast Guard, DHS. ACTION... Ship Terminal, mile marker 96.0 and the Southwest Pass Sea Buoy. The proposed moving safety zone..., mile marker 96.0, and the Southwest Pass Sea Buoy to address the increasing risk to safe...

  13. 77 FR 11168 - In the Matter of Exelon Corporation; Constellation Energy Group, Inc.; Nine Mile Nuclear Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... and the indirect license transfers. Constellation Energy Nuclear Group, LLC, shall inform the NRC in... Exelon Corporation; Constellation Energy Group, Inc.; Nine Mile Nuclear Station, LLC; Nine Mile Point... Indirect Transfer of Licenses I Nine Mile Point Nuclear Station, LLC (NMPNS, LLC, or the licensee) is...

  14. 33 CFR 165.T10-0693 - Regulated Navigation Area; Greenville Bridge Demolition, Lower Mississippi River, Mile 531.3.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...; Greenville Bridge Demolition, Lower Mississippi River, Mile 531.3. 165.T10-0693 Section 165.T10-0693... Bridge Demolition, Lower Mississippi River, Mile 531.3. (a) Regulated Navigation Area. The following is a regulated navigation area (RNA): All waters of the Lower Mississippi River beginning at mile 528 and...

  15. 33 CFR 165.T10-0693 - Regulated Navigation Area; Greenville Bridge Demolition, Lower Mississippi River, Mile 531.3.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...; Greenville Bridge Demolition, Lower Mississippi River, Mile 531.3. 165.T10-0693 Section 165.T10-0693... Bridge Demolition, Lower Mississippi River, Mile 531.3. (a) Regulated Navigation Area. The following is a regulated navigation area (RNA): All waters of the Lower Mississippi River beginning at mile 528 and...

  16. 75 FR 71061 - Drawbridge Operation Regulations; Bayou Liberty, Mile 2.0, St. Tammany Parish, Slidell, LA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulations; Bayou Liberty, Mile 2... the regulation governing the operation of the S433 bridge over Bayou Liberty, mile 2.0, St. Tammany... of the S433 bridge over Bayou Liberty, mile 2.0, St. Tammany Parish, Slidell, LA. This change...

  17. 76 FR 28311 - Drawbridge Operation Regulations; Bayou Liberty, Mile 2.0, St. Tammany Parish, Slidell, LA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Bayou Liberty, Mile 2.0, St. Tammany... deviation from the regulation governing the operation of the S433 Bridge over Bayou Liberty, mile 2.0, St... Bayou Liberty at mile 2.0, in St. Tammany Parish. The vertical clearance is 7.59 feet (2.31m) above...

  18. 76 FR 79145 - Drawbridge Operation Regulations; Bayou Liberty, Mile 2.0, St. Tammany Parish, Slidell, LA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulations; Bayou Liberty, Mile 2... operation of the SR 433 Bridge over Bayou Liberty, mile 2.0, St. Tammany Parish, Slidell, LA. The Louisiana... Notice of Proposed Rulemaking (NPRM) entitled ``Drawbridge Operation Regulations; Bayou Liberty, mile...

  19. 77 FR 26575 - Notice of the Establishment of the Ten Mile (Utah) Known Potash Leasing Area (KPLA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... Bureau of Land Management Notice of the Establishment of the Ten Mile (Utah) Known Potash Leasing Area... Ten Mile KPLA so the potash resources on these lands will no longer be available for non- competitive... prospecting permit applications that now lie within the boundaries of the Ten Mile KPLA. DATES: This...

  20. Vibrational frequencies and structural determinations of 1,4-thioxane

    NASA Astrophysics Data System (ADS)

    Ellzy, Michael W.; Jensen, James O.; Hameka, Hendrik F.; Kay, Jack G.; Zeroka, Daniel

    2001-10-01

    We present a detailed analysis of the structure and infrared spectra of 1,4-thioxane. The vibrational frequencies of the 1,4-thioxane molecule were analyzed using standard quantum chemical techniques. Frequencies were calculated at the MP2 and DFT levels of theory using the standard 6-31G* basis set. The structural transformation of the chemical agent bis (2-chloroethyl) sulfide (HD, mustard gas) and the related symmetry to a previously study compound (4) makes the symmetry of the 1,4-thioxane molecule an interesting candidate for study. The molecule exists normally in a C s configuration similar to the chair form of cyclohexane. High-energy forms of 1,4-thioxane with C 1 and C 2 symmetry also exist.

  1. Technical Fact Sheet – 1,4-Dioxane

    EPA Pesticide Factsheets

    This fact sheet, developed by the U.S. Environmental Protection Agency (EPA) Federal Facilities Restoration and Reuse Office (FFRRO), provides a brief summary of the contaminant 1,4-dioxane, including physical and chemical properties

  2. Evaluation of Algorithms for a Miles-in-Trail Decision Support Tool

    NASA Technical Reports Server (NTRS)

    Bloem, Michael; Hattaway, David; Bambos, Nicholas

    2012-01-01

    Four machine learning algorithms were prototyped and evaluated for use in a proposed decision support tool that would assist air traffic managers as they set Miles-in-Trail restrictions. The tool would display probabilities that each possible Miles-in-Trail value should be used in a given situation. The algorithms were evaluated with an expected Miles-in-Trail cost that assumes traffic managers set restrictions based on the tool-suggested probabilities. Basic Support Vector Machine, random forest, and decision tree algorithms were evaluated, as was a softmax regression algorithm that was modified to explicitly reduce the expected Miles-in-Trail cost. The algorithms were evaluated with data from the summer of 2011 for air traffic flows bound to the Newark Liberty International Airport (EWR) over the ARD, PENNS, and SHAFF fixes. The algorithms were provided with 18 input features that describe the weather at EWR, the runway configuration at EWR, the scheduled traffic demand at EWR and the fixes, and other traffic management initiatives in place at EWR. Features describing other traffic management initiatives at EWR and the weather at EWR achieved relatively high information gain scores, indicating that they are the most useful for estimating Miles-in-Trail. In spite of a high variance or over-fitting problem, the decision tree algorithm achieved the lowest expected Miles-in-Trail costs when the algorithms were evaluated using 10-fold cross validation with the summer 2011 data for these air traffic flows.

  3. 12 CFR 1.4 - Calculation of limits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Calculation of limits. (a) Calculation date. For purposes of determining compliance with 12 U.S.C. 24 (Seventh... change in the bank's capital category for purposes of 12 U.S.C. 1831o and 12 CFR 6.3. (b) Effective date... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Calculation of limits. 1.4 Section 1.4...

  4. 12 CFR 1.4 - Calculation of limits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Calculation of limits. (a) Calculation date. For purposes of determining compliance with 12 U.S.C. 24 (Seventh... change in the bank's capital category for purposes of 12 U.S.C. 1831o and 12 CFR 6.3. (b) Effective date... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Calculation of limits. 1.4 Section 1.4...

  5. Architecture Earth-Sheltered Buildings. Design Manual 1.4

    DTIC Science & Technology

    1984-03-01

    Bioclimat kpproach to Architectural Regionalismj Princeton, New Jersey, Princetk .niversity Press, 1963. " 7) 3. Givoni, B., Man, Climate and...AD-A 140 831 NAVFAC DM-1.4MARCH 1984 T OF ARCHITECTURE EARTH-SHELTERED BUILDINGS DESIGN MANUAL 1.4 Reproduced From Best Available Copy ~9J)O,3...design are included for the following disciplines: Planniing, Landscape Design, Life-Cycle Analysis, Architectural , Structural, Mechanical (criteria

  6. Acyloxylation of 1,4-Dioxanes and 1,4-Dithianes Catalyzed by a Copper-Iron Mixed Oxide.

    PubMed

    García-Cabeza, Ana Leticia; Marín-Barrios, Rubén; Moreno-Dorado, F Javier; Ortega, María J; Vidal, Hilario; Gatica, José M; Massanet, Guillermo M; Guerra, Francisco M

    2015-07-02

    The use of a copper-iron mixed oxide as a heterogeneous catalyst for the efficient synthesis of α-acyloxy-1,4-dioxanes and 1,4-dithianes employing t-butyl peroxyesters is reported. The preparation and characterization of the catalyst are described. The effect of the heteroatoms and a plausible mechanism are discussed. The method is operationally simple and involves low-cost starting materials affording products in good to excellent yields.

  7. Highest Resolution Image of Europa

    NASA Technical Reports Server (NTRS)

    1998-01-01

    During its twelfth orbit around Jupiter, on Dec. 16, 1997, NASA's Galileo spacecraft made its closest pass of Jupiter's icy moon Europa, soaring 200 kilometers (124 miles) kilometers above the icy surface. This image was taken near the closest approach point, at a range of 560 kilometers (335 miles) and is the highest resolution picture of Europa that will be obtained by Galileo. The image was taken at a highly oblique angle, providing a vantage point similar to that of someone looking out an airplane window. The features at the bottom of the image are much closer to the viewer than those at the top of the image. Many bright ridges are seen in the picture, with dark material in the low-lying valleys. In the center of the image, the regular ridges and valleys give way to a darker region of jumbled hills, which may be one of the many dark pits observed on the surface of Europa. Smaller dark, circular features seen here are probably impact craters.

    North is to the right of the picture, and the sun illuminates the surface from that direction. This image, centered at approximately 13 degrees south latitude and 235 degrees west longitude, is approximately 1.8 kilometers (1 mile) wide. The resolution is 6 meters (19 feet) per picture element. This image was taken on December 16, 1997 by the solid state imaging system camera on NASA's Galileo spacecraft.

    The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

    This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://www.jpl.nasa.gov/ galileo.

  8. Studies on Metabolism of 1,4-Dioxane

    DTIC Science & Technology

    2010-03-01

    acid. This proposal was based upon chemical oxidation experiments on dioxane using nitric acid originally conducted by Fairley and coworkers ( Fairley ...S., Holler, J., Richter, P. and Stevens, y.-w. 1996. Health evaluation of 1,4-dioxane. Toxicol. Ind. Health 12, 1-43. Fairley , A., Linton, E. C

  9. Sunspot 1520 Releases Strong (X1.4) Solar Flare

    NASA Video Gallery

    This movie shows the sun July 10-12, ending with the X1.4 class flare on July 12, 2012. It was captured by NASA’s Solar Dynamics Observatory in the 131 Angstrom wavelength - a wavelength that is...

  10. 17 CFR 1.4 - Use of electronic signatures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Use of electronic signatures... REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.4 Use of electronic signatures. For purposes of... broker, a pool participant or a client of a commodity trading advisor, an electronic signature...

  11. ER-1422: Biodegradation of 1,4-Dioxane

    DTIC Science & Technology

    2007-08-01

    Pseudonocardia sp. strain K1 was used to hydrolyze diglycolic acid, the free radical generator phenazine methosulfate was included in the assay, as reported... phenazine methosulfate is not a physiologically relevant compound and can not be involved in 1,4-dioxane mineralization in vivo. III. D. Discussion of

  12. 14 CFR Sec. 1-4 - System of accounts coding.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... General Accounting Provisions Sec. 1-4 System of accounts coding. (a) A four digit control number is... digit code assigned to each profit and loss account denote a detailed area of financial activity or... sequentially within blocks, designating more general classifications of financial activity and...

  13. [Obtaining antibodies to 1,4-dihydropyridine calcium channel blockers].

    PubMed

    Burkin, A A; Murkin, M A

    2008-01-01

    Immunization of rabbits with amlodipine conjugated with horseradish peroxidase resulted in raising polyclonal antibodies that allowed group determination of 1,4-dihydropyridine calcium channel blockers in aqueous solutions by ELISA with a sensitivity of 0.1 to 1.0 ng/ml for amlodipine, felodipine, nifedipine, and isradipine.

  14. [sup 137]Cs levels in deer following the Three Mile Island accident

    SciTech Connect

    Field, R.W. )

    1993-06-01

    White-tailed deer (Odocoileus virgianus) tongues were assayed to assess whether or not significant widespread [sup 137]Cs contamination occurred in the vicinity of Three Mile Island Nuclear Station as a result of the 1979 accident. White-tailed deer tongues harvested from 10 Pennsylvania counties more than 88 km away from Three Mile Island had significantly higher [sup 137]Cs levels than deer tongues harvested from counties surrounding the nuclear plant. The mean deer tongue [sup 137]Cs levels found in Pennsylvania white-tailed deer were lower than [sup 137]Cs levels found in deer from other parts of the US sampled shortly after culmination of major atmospheric nuclear testing. These findings support the conclusions of previous studies suggesting that only minimal quantities of [sup 137]Cs escaped from the damaged Three Mile Island plant after the accident.

  15. Ultrahigh Resolution Optical Coherence Tomography

    NASA Astrophysics Data System (ADS)

    Drexler, Wolfgang; Chen, Yu; Aguirre, Aaron D.; Považay, Boris; Unterhuber, Angelika; Fujimoto, James G.

    Since its invention in the late 1980s [1-4] and early 1990s [5-7], the original idea of OCT was to enable noninvasive optical biopsy, i.e., the in situ imaging of tissue microstructure with a resolution approaching that of histology, but without the need for tissue excision and post-processing. An important advance toward this goal was the introduction of ultrahigh-resolution OCT (UHR OCT). By improving axial OCT resolution by one order of magnitude from the 10 to 15 μm to the sub-μm region [8-11], UHR OCT enables superior visualization of tissue microstructure, including all major intraretinal layers in ophthalmic applications as well as cellular resolution OCT imaging in nontransparent tissue. This chapter reviews state-of-the-art technology that enables ultrahigh-resolution OCT covering the entire wavelength region from 500 to 1,600 nm and discusses fundamental limitations of OCT image resolution.

  16. 40 CFR 721.10678 - 1,4-Cyclohexanedicarboxylic acid, 1,4-dimethyl ester, hydrogenolysis products.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...-dimethyl ester, hydrogenolysis products. 721.10678 Section 721.10678 Protection of Environment..., 1,4-dimethyl ester, hydrogenolysis products. (a) Chemical substance and significant new uses subject... ester, hydrogenolysis products (PMN P-13-10; CAS No. 1373220-73-5) is subject to reporting under...

  17. Ambiphilic boron in 1,4,2,5-diazadiborinine

    PubMed Central

    Wang, Baolin; Li, Yongxin; Ganguly, Rakesh; Hirao, Hajime; Kinjo, Rei

    2016-01-01

    Boranes have long been known as the archetypal Lewis acids owing to an empty p-orbital on the boron centre. Meanwhile, Lewis basic tricoordinate boranes have been developed in recent years. Here we report the synthesis of an annulated 1,4,2,5-diazadiborinine derivative featuring boron atoms that exhibit both Lewis acidic and basic properties. Experimental and computational studies confirmed that two boron atoms in this molecule are spectroscopically equivalent. Nevertheless, this molecule cleaves C–O, B–H, Si–H and P–H bonds heterolytically, and readily undergoes [4+2] cycloaddition reaction with non-activated unsaturated bonds such as C=O, C=C, C≡C and C≡N bonds. The result, thus, indicates that the indistinguishable boron atoms in 1,4,2,5-diazadiborinine act as both nucleophilic and electrophilic centres, demonstrating ambiphilic nature. PMID:27279265

  18. Catalytic Asymmetric 1,4-Addition Reactions of Simple Alkylnitriles.

    PubMed

    Yamashita, Yasuhiro; Sato, Io; Suzuki, Hirotsugu; Kobayashi, Shū

    2015-10-01

    The development of catalytic asymmetric carbon-carbon bond-forming reactions of alkylnitriles that do not have an activating group at the α-position, under proton-transfer conditions, is a challenging research topic. Here, we report catalytic asymmetric direct-type 1,4-addition reactions of alkylnitriles with α,β-unsaturated amides by using a catalytic amount of potassium hexamethyldisilazide (KHMDS) with a chiral macro crown ether. The desired reactions proceeded in high yields with good diastereo- and enantioselectivities. To our knowledge, this is the first example of catalytic asymmetric direct-type 1,4-addition reaction of alkylnitriles without any activating group at the α-position.

  19. Synthesis and pharmacological activity of 1,4-benzodiazepine derivatives.

    PubMed

    Osman, A N; el-Gendy, A A; Omar, R H; Wagdy, L; Omar, A H

    2002-01-01

    2-Aminobenzamides (3a-g) were prepared starting with isatoic anhydride. These compounds reacted with chloroacetic acid to give (4a-g), which were cyclized by dicyclohexylcorbodiimide to afford (5a-g). The preliminary pharmacological screening revealed that some of the new 2H-1,4-benzodiazepin-3,5(1H,4H)-dione derivatives (5) exhibited CNS-depressant and anticonvulsant activities.

  20. 15N NMR of 1,4-dihydropyridine derivatives.

    PubMed

    Goba, Inguna; Liepinsh, Edvards

    2013-07-01

    In this article, we describe the characteristic (15)N and (1)HN NMR chemical shifts and (1)J((15)N-(1)H) coupling constants of various symmetrically and unsymmetrically substituted 1,4-dihydropyridine derivatives. The NMR chemical shifts and coupling constants are discussed in terms of their relationship to structural features such as character and position of the substituent in heterocycle, N-alkyl substitution, nitrogen lone pair delocalization within the conjugated system, and steric effects.

  1. GHB, GBL and 1,4-BD addiction.

    PubMed

    Brunt, Tibor M; van Amsterdam, Jan G C; van den Brink, Wim

    2014-01-01

    A growing body of evidence shows that gamma-hydroxybutyric acid (GHB) is an addictive substance. Its precursors gammabutyrolactone (GBL) and 1,4-butanediol (1,4-BD) show the same properties and may pose even more risks due to different pharmacokinetics. There are indications that problematic GHB use is increasing in the European Union. This review investigates the existing literature on the neurochemistry of GHB and its precursors, their acute toxicity, addiction potential and withdrawal, the proposed molecular mechanism underlying addiction and the treatment of withdrawal and addiction. Current evidence shows that GHB and its precursors are highly addictive, both in humans and animals, probably through a GABAB receptor related mechanism. Severity of withdrawal symptoms can be considered as a medical emergency. Recent studies suggest that benzodiazepines are not very effective, showing a high treatment resistance, whereas detoxification with pharmaceutical GHB proved to be successful. However, relapse in GHB use is frequent and more research is warranted on relapse prevention. This might aid medical practitioners in the field and improve general understanding of the severity of addiction to GHB, GBL and 1,4-BD.

  2. Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates.

    PubMed

    Vigante, Brigita; Rucins, Martins; Plotniece, Aiva; Pajuste, Karlis; Luntena, Iveta; Cekavicus, Brigita; Bisenieks, Egils; Smits, Rufus; Duburs, Gunars; Sobolev, Arkadij

    2015-11-12

    The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions. The use of TBD is crucial for the successful aminolysis of ethoxycarbonylmethyl ester of 1,4-dihydropyridines with secondary amines as without it the reaction does not proceed at all. The aminolysis reaction proceeded regioselectively, as the alkyl ester conjugated with the 1,4-dihydropyridine cycle was not involved in the reaction. Screening of other N-containing bases, such as triethylamine (TEA), pyridine, 4-(N,N-dimethylamino)pyridine (DMAP), 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), 1,5-diazabicyclo[4.3.0]non-5-ene (DBN), imidazole, tetramethyl guanidine (TMG) and 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD) as catalysts revealed no activity in the studied reaction.

  3. Spectroscopic investigations on the orientation of 1,4-dibromonaphthalene on silver nanoparticles.

    PubMed

    Geetha, K; Umadevi, M; Sathe, G V; Erenler, R

    2013-12-01

    Silver nanoparticles (Ag NPs) have been prepared by solution combustion method with glycine as fuel. Silver nanoparticles were characterized by X-Ray Diffraction (XRD), High Resolution Transmission Electron Microscopy (HRTEM) and UV-visible spectroscopy. The prepared silver nanoparticles exhibit cubic crystalline structure with grain size of 59 nm. HRTEM image shows that the silver nanoparticles have strain and four-fold symmetry formed by twinning in the crystal structure. The optical adsorption spectrum shows that the surface plasmon resonance peak of silver is observed at 380 nm. The orientation of 1,4-dibromonaphthlaene (1,4-DBrN) on silver nanoparticles has been inferred from nRs and SERS spectral features. The absence of a C-H stretching vibrations, the observed high intense C-H out-of-plane bending modes and high intense C-Br stretching vibration suggest that the 1,4-DBrN molecule may be adsorbed in a 'stand-on' orientation to the surface.

  4. Blueprint for Breakdown: Three Mile Island and the Media before the Accident.

    ERIC Educational Resources Information Center

    Friedman, Sharon M.

    1981-01-01

    Discusses media coverage of the Three Mile Island nuclear power plant before and during the disaster. Concludes that there was a communication breakdown prior to the accident. Outlines the causes and offers suggestions for avoiding similar breakdowns in the future. (JMF)

  5. A Content Analysis of News Media Coverage of the Accident at Three Mile Island.

    ERIC Educational Resources Information Center

    Stephens, Mitchell; Edison, Nadyne G.

    A study was conducted for the President's Commission on the Accident at Three Mile Island to analyze coverage of the accident by ten news organizations: two wire services, three commercial television networks, and five daily newspapers. Copies of all stories and transcripts of news programs during the first week of the accident were examined from…

  6. Emotional, Behavioral, and Physiological Effects of Chronic Stress at Three Mile Island.

    ERIC Educational Resources Information Center

    Baum, Andrew; And Others

    1983-01-01

    Evaluated the psychophysiological impact of Three Mile Island on nearby residents (N=38) compared to people living near an undamaged nuclear plant (N=32), a coal-fired plant (N=24) and a control group. Results indicated that residents of the TMI area exhibited more symptoms of stress a year after the accident. (WAS)

  7. Crisis contained, The Department of Energy at Three Mile Island: a history

    SciTech Connect

    Cantelon, P L; Williams, R C

    1980-12-01

    An account is given of the response of US DOE to the Three Mile Island-2 accident on March 28, 1979. The accident is treated as though it was a military battle. A synoptic chronologgy of the accident events and of DOE and other responses is included. (DLC)

  8. 33 CFR 110.55a - Five Mile River, Norwalk and Darien, Conn.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Island at latitude 41°03′27.5″ N., longitude 73°26′52″ W.; thence following the shoreline northerly along... following the shoreline southerly along the easterly side of Five Mile River to a point on the...

  9. Leveraging socially networked mobile ICT platforms for the last-mile delivery problem.

    PubMed

    Suh, Kyo; Smith, Timothy; Linhoff, Michelle

    2012-09-04

    Increasing numbers of people are managing their social networks on mobile information and communication technology (ICT) platforms. This study materializes these social relationships by leveraging spatial and networked information for sharing excess capacity to reduce the environmental impacts associated with "last-mile" package delivery systems from online purchases, particularly in low population density settings. Alternative package pickup location systems (PLS), such as a kiosk on a public transit platform or in a grocery store, have been suggested as effective strategies for reducing package travel miles and greenhouse gas emissions, compared to current door-to-door delivery models (CDS). However, our results suggest that a pickup location delivery system operating in a suburban setting may actually increase travel miles and emissions. Only once a social network is employed to assist in package pickup (SPLS) are significant reductions in the last-mile delivery distance and carbon emissions observed across both urban and suburban settings. Implications for logistics management's decades-long focus on improving efficiencies of dedicated distribution systems through specialization, as well as for public policy targeting carbon emissions of the transport sector are discussed.

  10. 6. ALABAMA, PICKENS CO., COCHRANE RAILROAD BRIDGE 1.5 miles N. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. ALABAMA, PICKENS CO., COCHRANE RAILROAD BRIDGE 1.5 miles N. from Cochrane on Ala. route 17 Copy of photo by Jack Donnell, Columbus, Ms., 192. Shows center turn span and part of one fixed span. Sarcone Photography, Columbus, Ms. Sep 1978. - Bridges of the Upper Tombigbee River Valley, Cochrane, Pickens County, AL

  11. 5. ALABAMA, PICKENS CO., COCHRANE COLLAPSED RAILROAD BRIDGE 1.5 miles ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. ALABAMA, PICKENS CO., COCHRANE COLLAPSED RAILROAD BRIDGE 1.5 miles N. from Cochrane on Ala. route 17. Copy of photo by Jack Donnell, Columbus, Ms., after bridge collapsed in 1973. Shows broken turn span and overturned center pier. Sarcone Photography, Columbus, Ms. Sep 1978. - Bridges of the Upper Tombigbee River Valley, Cochrane, Pickens County, AL

  12. 2. ALABAMA, PICKENS, CO., COCHRANE HIGHWAY BRIDGE 1.5 miles N. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. ALABAMA, PICKENS, CO., COCHRANE HIGHWAY BRIDGE 1.5 miles N. from Cochrane on Ala. route 17. Aerial view of Milner bridge, from SE. David J. Kaminsky, Architecturl Photography, Atlanta Ga. Aug 1978. - Bridges of the Upper Tombigbee River Valley, Cochrane, Pickens County, AL

  13. 4. ALABAMA, PICKENS CO., COCHRANE COLLAPSED RAILROAD BRIDGE 1.5 miles ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. ALABAMA, PICKENS CO., COCHRANE COLLAPSED RAILROAD BRIDGE 1.5 miles N. from Cochrane on Ala. route 17. Western half of collapsed Alabama, Tenn. & Northern RR. Bridge Jack Donnell, Columbus, Ms., photographer, 1973. Copy by Sarcone Photography, Columbs, Ms Sep 1978. - Bridges of the Upper Tombigbee River Valley, Cochrane, Pickens County, AL

  14. 1. ALABAMA, PICKENS CO., COCHRANE HIGHWAY BRIDGE 1.5 miles N. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. ALABAMA, PICKENS CO., COCHRANE HIGHWAY BRIDGE 1.5 miles N. from Cochrane on Ala. route 17 Aerial view of Milner bridge, from SW. David J. Kaminsky, Architectural Photography, Atlanta Ga. Aug 1978. - Bridges of the Upper Tombigbee River Valley, Cochrane, Pickens County, AL

  15. What If We Kept Our Cars Parked For Trips Less Than One Mile?

    EPA Pesticide Factsheets

    This EPA fact sheet explores the possibility of walking or biking for half of our car trips under a mile, cutting fuel consumption, fuel costs and lowering CO2 emissions, plus the benefits of physical activity. (EPA publication # EPA-420-F-15-021)

  16. Mary Miles Bibb: Education and Moral Improvement in the "Voice of the Fugitive."

    ERIC Educational Resources Information Center

    Tripp, Bernell E.

    An ardent antislavery supporter and teacher, Mary Elizabeth Miles Bibb (c.1820-1877) knew the significance of an education and the purpose it would serve, in the classroom and in the newsroom, in establishing a better life for blacks prior to the Civil War. In 1847, her antislavery involvement allowed her to meet her future husband, Henry Bibb,…

  17. Extending Miles & Snow's strategy choice typology to the German hospital sector.

    PubMed

    Helmig, Bernd; Hinz, Vera; Ingerfurth, Stefan

    2014-12-01

    Hospitals' strategy choices represent highly relevant factors that affect organizational performance and survival. This study assesses the differences among hospitals' strategic choices. This strategy definition and assessment reflects the typology proposed by Miles and Snow, who distinguish four strategy types: defender, analyzer, prospector, and reactor. Synthesis of empirical evidence from previous studies that have applied Miles and Snow's typology in the hospital sector using various methodological approaches and measures provides hints for industry-specific patterns and avenues for further research. Taking an extended view of strategic choice, the authors conduct an empirical survey of a sample of 178 German hospitals. The authors apply a multi-item measure of the Miles and Snow strategy types in the hospital sector and identify hybrid strategy types that deviate from the four strategy types defined by Miles and Snow. Overall, seven distinct strategy types emerge from this analysis. There exist three distinct hybrid types in particular. Strategy choice is systematically related to hospital size and teaching status but not to ownership and location. The significant variance in performance for the seven different strategy types justifies the distinction between them. The results support the idea of industry-specific strategy choices. Policy makers should analyze the structural context in which hospitals operate and intervene through political and regulatory means.

  18. Influence of Miles City Line 1 on the United States Hereford Population

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The goal of this research was to document the influence of Line 1 (L1) Hereford cattle developed by the United States Department of Agriculture at its research facility in Miles City, Montana, on the United States Hereford population. The L1 Hereford population originated in 1934 and has been therea...

  19. Accuracy and Generalizability in Summaries of Affect Regulation Strategies: Comment on Webb, Miles, and Sheeran (2012)

    ERIC Educational Resources Information Center

    Augustine, Adam A.; Hemenover, Scott H.

    2013-01-01

    In their examination of the effectiveness of affect regulation strategies, Webb, Miles, and Sheeran (2012) offered the results of a broad meta-analysis of studies on regulatory interventions. Their analysis provides an alternative to our earlier, more focused meta-analysis of the affect regulation literature (Augustine & Hemenover, 2009).…

  20. Integrating management techniques to restore sites invaded by mile-a-minute weed, Persicaria perfoliata

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Efforts to suppress an invasive weed are often undertaken with the goal of facilitating the recovery of a diverse native plant community. In some cases, however, reduction in the abundance of the target weed results in an increase in other exotic weeds. Mile-a-minute weed, Persicaria perfoliata (L.)...

  1. 76 FR 41725 - Proposed Amendment of Class E Airspace; Miles City, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... rulemaking (NPRM). SUMMARY: This action proposes to modify Class E airspace at Frank Wiley Field, Miles City... instrument approach procedures at Frank Wiley Field. Additionally, the geographic coordinates for Frank Wiley... airspace and Class E airspace extending upward from 700 feet above the surface at Frank Wiley Field,...

  2. 76 FR 57633 - Amendment of Class E Airspace; Miles City, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... System (GPS) standard instrument approach procedures at Frank Wiley Field. Additionally, the geographic coordinates for Frank Wiley Field are being adjusted. This improves the safety ] and management of Instrument... surface, at Frank Wiley Field, Miles City, MT, to accommodate IFR aircraft executing new RNAV...

  3. EAARL topography-Three Mile Creek and Mobile-Tensaw Delta, Alabama, 2010

    USGS Publications Warehouse

    Nayegandhi, Amar; Bonisteel-Cormier, J.M.; Clark, A.P.; Wright, C.W.; Brock, J.C.; Nagle, D.B.; Vivekanandan, Saisudha; Fredericks, Xan

    2011-01-01

    This DVD contains lidar-derived first-surface (FS) and bare-earth (BE) topography GIS datasets of a portion of the Mobile-Tensaw Delta region and Three Mile Creek in Alabama. These datasets were acquired on March 6, 2010.

  4. Three Mile Island technical information and examination program instrumentation and electrical summary report

    SciTech Connect

    Meininger, R.D.

    1985-07-01

    This report summarizes the investigations on instrumentation and electrical systems that were subjected to a loss-of-coolant accident environment during and following the accident at Three Mile Island Unit-2 (TMI-2) on March 28, 1979. The report is a summary of information previously published in GEND-INF reports, plus current knowledge of the investigators.

  5. Marie Zimmermann Farm, U.S. Route 209, 5 Miles Southwest of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Marie Zimmermann Farm, U.S. Route 209, 5 Miles Southwest of Milford. The property is defined at its northern boundary by Zimmermann Road and at the west by Long Meadow Road. The east boundary of the parcel is the edge of the Delaware River. The south edge of the parcel is irregularly oriented east-to-west. , Milford, Pike County, PA

  6. Development of a high-resolution bathymetry dataset for the Columbia River through the Hanford Reach

    SciTech Connect

    Coleman, Andre M.; Ward, Duane L.; Larson, Kyle B.; Lettrick, Joseph W.

    2010-10-08

    A bathymetric and topographic data collection and processing effort involving existing and newly collected data has been performed for the Columbia River through the Hanford Reach in central Washington State, extending 60-miles from the tailrace of Priest Rapids Dam (river mile 397) to near the vicinity of the Interstate 182 bridge just upstream of the Yakima River confluence (river mile 337). The contents of this report provide a description of the data collections, data inputs, processing methodology, and final data quality assessment used to develop a comprehensive and continuous merged 1m resolution bathymetric and topographic surface dataset for the Columbia River through the Hanford Reach.

  7. Methodology for Calculating Cost-per-Mile for Current and Future Vehicle Powertrain Technologies, with Projections to 2024: Preprint

    SciTech Connect

    Ruth, M.; Timbario, T. A.; Timbario, T. J.; Laffen, M.

    2011-01-01

    Currently, several cost-per-mile calculators exist that can provide estimates of acquisition and operating costs for consumers and fleets. However, these calculators are limited in their ability to determine the difference in cost per mile for consumer versus fleet ownership, to calculate the costs beyond one ownership period, to show the sensitivity of the cost per mile to the annual vehicle miles traveled (VMT), and to estimate future increases in operating and ownership costs. Oftentimes, these tools apply a constant percentage increase over the time period of vehicle operation, or in some cases, no increase in direct costs at all over time. A more accurate cost-per-mile calculator has been developed that allows the user to analyze these costs for both consumers and fleets. The calculator was developed to allow simultaneous comparisons of conventional light-duty internal combustion engine (ICE) vehicles, mild and full hybrid electric vehicles (HEVs), and fuel cell vehicles (FCVs). This paper is a summary of the development by the authors of a more accurate cost-per-mile calculator that allows the user to analyze vehicle acquisition and operating costs for both consumer and fleets. Cost-per-mile results are reported for consumer-operated vehicles travelling 15,000 miles per year and for fleets travelling 25,000 miles per year.

  8. Photoluminescent carbon dots from 1,4-addition polymers.

    PubMed

    Jiang, Zhiqiang; Nolan, Andrew; Walton, Jeffrey G A; Lilienkampf, Annamaria; Zhang, Rong; Bradley, Mark

    2014-08-25

    Photoluminescent carbon dots were synthesised directly by thermopyrolysis of 1,4-addition polymers, allowing precise control of their properties. The effect of polymer composition on the properties of the carbon dots was investigated by TEM, IR, XPS, elemental analysis and fluorescence analysis, with carbon dots synthesised from nitrogen-containing polymers showing the highest fluorescence. The carbon dots with high nitrogen content were observed to have strong fluorescence in the visible region, and culture with cells showed that the carbon dots were non-cytotoxic and readily taken up by three different cell lines.

  9. Mineral resources of the Fifteen Mile Creek, Oregon Canyon, Twelve Mile Creek, and Willow Creek Wilderness Study Areas, Malheur and Harney counties, Oregon

    SciTech Connect

    Peterson, J.A.; Rytuba, J.J.; Plouff, D.; Vercountere, T.L.; Turner, R.L.; Sawatzky, D.L. ); Leszcykowski, A.M.; Peters, T.J.; Schmauch, S.W.; Winters, R.A. )

    1988-01-01

    The four contiguous study areas are located in a volcanic terrane dominated by tuffs that were erupted from calderas of the McDermitt Caldera complex and the Whitehorse Caldera. None of these areas have identified resources, despite the proximity of mercury, uranium, and lithium mineralization to the south. The southern parts of the Fifteen Mile Creek and the Oregon Canyon Wilderness Study Areas have a low potential for mercury and uranium. The southern parts of the Fifteen Mile Creek, Oregon Canyon, and Willow Creek and the northwestern part of the Oregon Wilderness Study Areas have low potential for antimony, bismuth, mercury, silver,molybdenum, and zinc. In the Oregon Canyon Wilderness Study Area, the tuff of Oregon Canyon and the rim of the caldera of the McDermitt Caldera complex have a low potential for gold and silver in epithermal veins. The study areas have a low potential for zeolite minerals, oil and gas, and geothermal energy throughout, and restricted parts of the study areas have a low potential for pumice, rare-earth elements, zirconium, and decorative building stone.

  10. The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates beta-1,4- and beta-1,3-1,4-mixed linked glucans at a single binding site.

    PubMed

    Carvalho, Ana L; Goyal, Arun; Prates, José A M; Bolam, David N; Gilbert, Harry J; Pires, Virgínia M R; Ferreira, Luís M A; Planas, Antoni; Romão, Maria J; Fontes, Carlos M G A

    2004-08-13

    Modular glycoside hydrolases that attack recalcitrant polymers generally contain noncatalytic carbohydrate-binding modules (CBMs), which play a critical role in the action of these enzymes by localizing the appended catalytic domains onto the surface of insoluble polysaccharide substrates. Type B CBMs, which recognize single polysaccharide chains, display ligand specificities that are consistent with the substrates hydrolyzed by the associated catalytic domains. In enzymes that contain multiple catalytic domains with distinct substrate specificities, it is unclear how these different activities influence the evolution of the ligand recognition profile of the appended CBM. To address this issue, we have characterized the properties of a family 11 CBM (CtCBM11) in Clostridium thermocellum Lic26A-Cel5E, an enzyme that contains GH5 and GH26 catalytic domains that display beta-1,4- and beta-1,3-1,4-mixed linked endoglucanase activity, respectively. Here we show that CtCBM11 binds to both beta-1,4- and beta-1,3-1,4-mixed linked glucans, displaying K(a) values of 1.9 x 10(5), 4.4 x 10(4), and 2 x 10(3) m(-1) for Glc-beta1,4-Glc-beta1,4-Glc-beta1,3-Glc, Glc-beta1,4-Glc-beta1,4-Glc-beta1,4-Glc, and Glc-beta1,3-Glc-beta1,4-Glc-beta1,3-Glc, respectively, demonstrating that CBMs can display a preference for mixed linked glucans. To determine whether these ligands are accommodated in the same or diverse sites in CtCBM11, the crystal structure of the protein was solved to a resolution of 1.98 A. The protein displays a beta-sandwich with a concave side that forms a potential binding cleft. Site-directed mutagenesis revealed that Tyr(22), Tyr(53), and Tyr(129), located in the putative binding cleft, play a central role in the recognition of all the ligands recognized by the protein. We propose, therefore, that CtCBM11 contains a single ligand-binding site that displays affinity for both beta-1,4- and beta-1,3-1,4-mixed linked glucans.

  11. Reactivity initiated accident test series Test RIA 1-4

    SciTech Connect

    Martinson, Z.R.; El-Genk, M.S.; Fukuda, S.K.; LaPointe, R.E.; Osetek, D.J.

    1980-05-01

    The Reactivity Initiated Accident (RIA) Test RIA 1-4, the first 9-rod fuel rod bundle RIA Test to be performed at BWR hot startup conditions, was completed on April 16, 1980. The test was performed in the Power Burst Facility (PBF). Objective for Test RIA 1-4 was to provide information regarding loss-of-coolable fuel rod geometry following a RIA event for a peak fuel enthalpy equivalent to the present licensing criteria of 280 cal/g. The most severe RIA is the postulated Boiling Water Reactor (BWR) control rod drop during reactor startup. Therefore the test was conducted at BWR hot startup coolant conditions (538 K, 6.45 MPa, 0.8 1/sec). The test sequence began with steady power operation to condition the fuel, establish a short-lived fission product inventory, and calibrate the calorimetric measurements and core power chambers, neutron flux and gamma flux detectors. The test train was removed from the in-pile tube (IPT) to replace one of the fuel rods with a nominally identical irradiated rod and twelve flux wire monitors. A 2.8 ms period power burst was then performed. Coolant flow measurements were made before and after the power burst to characterize the flow blockage that occurred as a result of fuel rod failure.

  12. 1. 4 gigahertz luminosity function and its evolution

    SciTech Connect

    Condon, J. J.

    1989-03-01

    The local luminosity function was determined at v = 1.4 GHz from radio observations of two low-redshift galaxy samples: (1) spiral and irregular galaxies with apparent blue magnitudes and declinations and (2) galaxies of all morphologies with blue angular diameters of 1.0 arcmin or greater in the declination range between -2.5 deg and +82 deg. Separate luminosity functions for the radio source populations powered by 'starbursts' and 'monsters' were obtained from the latter sample. The amount of evolution required for the local luminosity function to account for the faint sources is discussed. The cosmological evolution of extragalactic radio sources appears to be so strong at all observed luminosities that the local luminosity function and counts of all sources between S of roughly 10 micro-Jy and S of roughly 10 Jy at v = 1.4 GHz can be matched with a model in which most sources are confined to a hollow shell with z of roughly 0.8. 36 refs.

  13. Microwave backscatter and emission observed from Shuttle Imaging Radar B and an airborne 1.4 GHz radiometer

    NASA Technical Reports Server (NTRS)

    Wang, J. R.; Schiue, J. C.; Schmugge, T. J.; Engman, E. T.; Mo, T.; Lawrence, R. W.

    1985-01-01

    A soil moisture experiment conducted with the Shuttle Imaging Radar B (SIR-B) is reported. SIR-B operated at 1.28 GHz provided the active microwave measurements, while a 4-beam pushbroom 1.4 GHz radiometer gave the complementary passive microwave measurements. The aircraft measurements were made at an altitude of 330 m, resulting in a ground resolution cell of about 100 m diameter. SIR-B ground resolution from 225 km was about 35 m. More than 150 agricultural fields in the San Joaquin Valley of California were examined in the experiment. The effect of surface roughness height on radar backscatter and radiometric measurements was studied.

  14. 40 CFR 55.14 - Requirements that apply to OCS sources located within 25 miles of States' seaward boundaries, by...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... located within 25 miles of States' seaward boundaries, by State. 55.14 Section 55.14 Protection of... REGULATIONS § 55.14 Requirements that apply to OCS sources located within 25 miles of States' seaward... requirements. State and local requirements promulgated by EPA as applicable to OCS sources located within...

  15. Survey of Yucca Mountain, Forty-Mile Canyon, and Jackass Flats in Nye County, Nevada for desert tortoise, Gopherus agassizii

    SciTech Connect

    Medica, P.A.; O`Farrell, T.P.; Collins, E.

    1981-10-01

    The objective of this brief survey was to determine if G. agassizii is present west of Forty-Mile Canyon in the Yucca Mountain.. area, or along the major access roads which lead through Jackass Flats to Forty-Mile Canyon and Yucca Mountain

  16. Answers to frequently asked questions about cleanup activities at Three Mile Island, Unit 2. Public information report

    SciTech Connect

    Not Available

    1980-09-01

    The document presents answers to frequently asked questions about plans for cleanup and decontamination activities at Three Mile Island, Unit 2. Answers to the questions asked are based on information in the NRC 'Draft Programmatic Environmental Impact Statement related to decontamination and disposal of radioactive wastes resulting from March 28, 1979, accident, Three Mile Island Nuclear Station, Unit 2,' NUREG-0683.

  17. 33 CFR 165.820 - Security Zone; Ohio River Mile, 34.6 to 35.1, Shippingport, Pennsylvania.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zone; Ohio River Mile... Guard District § 165.820 Security Zone; Ohio River Mile, 34.6 to 35.1, Shippingport, Pennsylvania. (a) Location. The following area is a security zone: The waters of the Ohio River, extending 200 feet from...

  18. 76 FR 28386 - Safety Zone: Ohio River Mile 355.5 to 356.5 Portsmouth, OH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone: Ohio River Mile 355.5 to 356.5 Portsmouth... to establish a safety zone in the Ohio Valley Captain of the Port Zone on the Ohio River in.... Fireworks will be launched from the left descending bank on the Ohio River at mile 356. A...

  19. 33 CFR 165.820 - Security Zone; Ohio River Mile, 34.6 to 35.1, Shippingport, Pennsylvania.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Security Zone; Ohio River Mile... Guard District § 165.820 Security Zone; Ohio River Mile, 34.6 to 35.1, Shippingport, Pennsylvania. (a) Location. The following area is a security zone: The waters of the Ohio River, extending 200 feet from...

  20. 25 CFR 39.711 - How does a school calculate annual bus transportation miles for residential students?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How does a school calculate annual bus transportation... Transportation Miles § 39.711 How does a school calculate annual bus transportation miles for residential... driven for all buses used to transport students from their homes to the school. If a school...

  1. 25 CFR 39.711 - How does a school calculate annual bus transportation miles for residential students?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How does a school calculate annual bus transportation... Transportation Miles § 39.711 How does a school calculate annual bus transportation miles for residential... driven for all buses used to transport students from their homes to the school. If a school...

  2. 25 CFR 39.711 - How does a school calculate annual bus transportation miles for residential students?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How does a school calculate annual bus transportation... Transportation Miles § 39.711 How does a school calculate annual bus transportation miles for residential... driven for all buses used to transport students from their homes to the school. If a school...

  3. 25 CFR 39.711 - How does a school calculate annual bus transportation miles for residential students?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true How does a school calculate annual bus transportation... Transportation Miles § 39.711 How does a school calculate annual bus transportation miles for residential... driven for all buses used to transport students from their homes to the school. If a school...

  4. 25 CFR 39.711 - How does a school calculate annual bus transportation miles for residential students?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How does a school calculate annual bus transportation... Transportation Miles § 39.711 How does a school calculate annual bus transportation miles for residential... driven for all buses used to transport students from their homes to the school. If a school...

  5. 76 FR 38975 - Safety Zone; Upper Mississippi River, Mile 856.0 to 855.0, Minneapolis, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Upper Mississippi River, Mile 856.0 to 855... is establishing a temporary safety zone for all waters of the Upper Mississippi River, from Mile 856... Upper Mississippi River. Entry into this zone is prohibited unless specifically authorized by...

  6. Mile-a-minute weed (Persicaria perfoliata) and weevil (Rhinoncomimus latipes) response to varying moisture and temperature conditions

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The combined effects of herbivory and water stress on growth and reproduction of mile-a-minute weed (Persicaria perfoliata (L.) H. Gross) were investigated in greenhouse trials over two years, with well-watered or water-limited plants either exposed or not exposed to herbivory by the mile-a-minute w...

  7. 33 CFR 165.T08-0315 - Safety Zone; Upper Mississippi River, Mile 183.0 to 183.5.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Safety Zone; Upper Mississippi... Guard District § 165.T08-0315 Safety Zone; Upper Mississippi River, Mile 183.0 to 183.5. (a) Location. The following area is a safety zone: All waters of the Upper Mississippi River, mile 183.0 to...

  8. 33 CFR 165.839 - Safety Zone; Large Cruise Ships; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans, LA. 165.839 Section...; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans, LA. (a) Location. Within the Lower Mississippi River and Southwest Pass, moving safety zones are established around...

  9. 33 CFR 165.839 - Safety Zone; Large Cruise Ships; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans, LA. 165.839 Section...; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans, LA. (a) Location. Within the Lower Mississippi River and Southwest Pass, moving safety zones are established around...

  10. 76 FR 43226 - Drawbridge Operation Regulations; Bayou Liberty, Mile 2.0, St. Tammany Parish, Slidell, LA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulations; Bayou Liberty, Mile 2... (S433) bridge across Liberty Bayou, mile 2.0, at Slidell, St. Tammany Parish, Louisiana. The proposed... Development (LDOTD), the owner of the bridge, replaced the existing S433 pontoon bridge over Bayou...

  11. 78 FR 62329 - Special Local Regulation; Tennessee River, Miles 255.0 to 256.5, Florence, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-17

    ... temporary special local regulation for the waters of the Tennessee River beginning at mile marker 255.0 and... the Tennessee River, beginning at mile marker 255.0 and ending at 256.5, during the Shoals Dragonboat... discussed in the preamble, the U.S. Coast Guard amends 33 CFR Part 100 as follows: PART 100--SAFETY OF...

  12. Changes in cardiopulmonary function in normal adults after the Rockport 1 mile walking test: a preliminary study.

    PubMed

    Kim, Kyoung; Lee, Hye-Young; Lee, Do-Youn; Nam, Chan-Woo

    2015-08-01

    [Purpose] The purpose of this study was to investigate the changes of cardiopulmonary function in normal adults after the Rockport 1 mile walking test. [Subjects and Methods] University students (13 males and 27 females) participated in this study. Before and after the Rockport 1 mile walking test, pulmonary function, respiratory pressure, and maximal oxygen uptake were measured. [Results] Significant improvements in forced vital capacity and maximal inspiratory pressure were observed after the Rockport 1 mile walking test in males, and significant improvements in forced vital capacity, forced expiratory volume at 1 s, maximal inspiratory pressure, and maximal expiratory pressure were observed after the Rockport 1 mile walking test in females. However, the maximal oxygen uptake was not significantly different. [Conclusion] Our findings indicate that the Rockport 1 mile walking test changes cardiopulmonary function in males and females, and that it may improve cardiopulmonary function in middle-aged and older adults and provide basic data on cardiopulmonary endurance.

  13. 1,4-diphenylbutadiyne as a potential tritium getter

    SciTech Connect

    Miller, H.H.; Bissell, E.E.; Tsugawa, R.T.; Souers, P.C.

    1980-10-01

    Research on the acetylene compound 1,4-diphenylbutadiyne is an effort to develop an air-operative tritium gas scavenger. T/sub 2/ adds to the acetylene bond of the organic in the presence of a metal catalyst. The catalyst also stimulates the oxidation reaction as well. The butadiyne compound has shown good reaction efficiency at 300 ppM T/sub 2/ in static dry air. At this concentration 75% of the scavenged tritium was in the organic. This work has expanded to the investigation of liquid acetylenes, metal acetylene complexes, organometallics and acetylene based alcohols. The best of these compounds has gettered 100% of 10 to 500 ppM T/sub 2/ for both static and dynamic air flow conditions.

  14. Photophysics and photochemical studies of 1,4-dihydropyridine derivatives.

    PubMed

    Pávez, Paulina; Encinas, Maria Victoria

    2007-01-01

    The absorption and fluorescence properties of nifedipine (NPDHP), felodipine (CPDHP) and a series of structurally related 1,4-dihydropyridines were studied in aqueous solution and organic solvents of different properties. The absorption and fluorescence spectra were found to depend on the chemical nature of the substituents at the position 4 of the 1,4-dihydropyridine ring (DHP) and on solvent properties. In aqueous solution, the fluorescence spectra of 4-phenyl substituted compounds are blue-shifted with respect to the alkyl substituted compounds. The more fluorescent compound is CPDHP. Nifedipine is not fluorescent. All compounds, with the exception of CPDHP, present monoexponential fluorescence decay with very short lifetime (0.2-0.4 ns). CPDHP showed a biexponential emission decay with a long-lived component of 1.7 ns; this behavior is explained in terms of different conformers because of the hindered rotation of the phenyl group by the ortho-substitution. Analysis of the solvent effect on the maximum of the absorption spectrum by using the linear solvent-energy relation solvato-chromic equation indicates the redshifts are influenced by the polarizability, hydrogen bonding ability and the hydrogen bond acceptance of the solvent. Whereas, the fluorescence characteristics (spectra, quantum yields and lifetimes) are sensitive to the polarizabilty and hydrogen bond ability of the solvents. Photo-decomposition of nifedipine is dependent on the solvent properties. Faster decomposition rates were obtained in nonprotic solvents. The 4-carboxylic derivative goes to decarboxylation. Under similar conditions, the other DHP compounds did not show appreciable photodecomposition.

  15. Theoretical modeling of the MILES hit profiles in military weapon low-data rate simulators

    NASA Astrophysics Data System (ADS)

    Andrews, L. C.; Phillips, R. L.; Smith, C. A.; Belichki, S. B.; Crabbs, R.; Cofarro, J. T.; Fountain, W.; Tucker, F. M.; Parrish, B. J.

    2016-09-01

    Math modeling of a low-data-rate optical communication system is presented and compared with recent testing results over ranges up to 100 m in an indoor tunnel at Kennedy Space Center. Additional modeling of outdoor testing results at longer ranges in the open atmosphere is also presented. The system modeled is the Army's Multiple Integrated Laser Engagement System (MILES) that has been used as a tactical training system since the early 1980s. The objective of the current modeling and testing is to obtain target hit zone profiles for the M16A2/M4 rifles and establish a data baseline for MILES that will aid in its upgrade using more recently developed lasers and detectors.

  16. Four Mile Creek semi-annual sampling report, July 1992 sampling event

    SciTech Connect

    Not Available

    1992-10-14

    From 1955 to 1988 low-level radioactive wastewater generated by chemical separation processes within the General Separations Area (GSA) were discharged to seepage basins in the F and H Areas of the Savannah River Site (SRS). These basins were designed to permit the infiltration of the process wastewaters. As wastewater percolated downward through the basins, chemical and radioactive constituents were retained or delayed in the subsoils. An extensive study aimed at characterizing the groundwater seeping into Four Mile Creek and its associated seepline was conducted in 1988 and 1989 (Haselow et al. 1990). Results of this study suggested that contaminants leaching from the F and H Area seepage basins were impacting the Four Mile Creek wetland system.

  17. Overview view of MoronytpRainbow Line (right) about onefourth mile northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Overview view of Morony-tp-Rainbow Line (right) about one-fourth mile northeast of Rainbow Dam. Ryan-to-Rainbow Lines 1 and 2 at center, Cochrane-to-Rainbow Line at left and Rainbow Dam in background right of center. View to southwest - Morony Hydroelectric Facility, Morony-to-Rainbow 100 kV Transmission Line, West bank of the Missouri River, Great Falls, Cascade County, MT

  18. Mediating influences of social support on stress at Three Mile Island.

    PubMed

    Fleming, R; Baum, A; Gisriel, M M; Gatchel, R J

    1982-09-01

    Symptom reporting, task performance, and urinary catecholamine excretion were studied in a group of people living near the Three Mile Island nuclear power plant and in control populations. More than a year after the accident, living near the damaged reactor was associated with elevations in all indices of stress compared with control levels. Social support mediated these stress indices such that higher levels were associated with fewer psychological and behavioral symptoms of stress. Biochemical measures showed a different pattern of results.

  19. Summary Report of Commercial reactor Criticality Data for Three Mile Island Unit 1

    SciTech Connect

    Larry B. Wimmer

    2001-08-29

    The objective of the ''Summary Report of Commercial Reactor Criticality Data for Three Mile Island Unit I'' is to present the CRC data for the TMI-1 reactor. Results from the CRC evaluations will support the development and validation of the neutronics models used for criticality analyses involving commercial spent nuclear fuel. These models and their validation are discussed in the ''Disposal Criticality Analysis Methodology Topical Report'' (YMP 2000).

  20. A 2,000-mile partnership with the USGS, Kayaks down the Yukon

    USGS Publications Warehouse

    Schuster, P.; Reddy, M.

    2003-01-01

    Early in 2001, Bill Barber and Jay Klinck, avid kayakers and scientists, began planning a northern expedition that would take them across more than 2,000 miles of mostly untamed wilderness along the Yukon River. At the same time, USGS scientists were making plans to study the last, unregulated great river in North America, spanning one of the largest and most diverse ecosystems in the world. Soon, the paths of kayakers and scientists would cross.

  1. From it's position at 175 statute miles above Earth, the Space Shuttle Endeavour has encountered

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-77 ESC VIEW --- From it's position at 175 statute miles above Earth, the Space Shuttle Endeavour has encountered some colorful and attractive scenes heading into sunsets and sunrises. This particular encounter, captured with an Electronic Still Camera (ESC), occurred on flight day four, during which the six-member crew deployed the Passive Aerodynamically Stabilized Magnetically Damped Satellite (PAMS) - Satellite Test Unit (STU). GMT: 13:48:47.

  2. Examination results of the Three Mile Island radiation detector HP-R-212

    SciTech Connect

    Mueller, G M

    1984-01-01

    Area radiation detector HP-R-212 was removed from the Three Mile Island containment building on November 13, 1981. The detector apparently started to fail during November 1979 and by the first part of December 1979 the detector readings had degraded from 1 R/h to 20 mR/h. This report discusses the cause of ailure, detector radiation measurement characteristics, and our estimates of the total gamma radiation dose received by the detector electronics.

  3. High Resolution Globe of Jupiter

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This true-color simulated view of Jupiter is composed of 4 images taken by NASA's Cassini spacecraft on December 7, 2000. To illustrate what Jupiter would have looked like if the cameras had a field-of-view large enough to capture the entire planet, the cylindrical map was projected onto a globe. The resolution is about 144 kilometers (89 miles) per pixel. Jupiter's moon Europa is casting the shadow on the planet.

    Cassini is a cooperative mission of NASA, the European Space Agency and the Italian Space Agency. JPL, a division of the California Institute of Technology in Pasadena, manages Cassini for NASA's Office of Space Science, Washington, D.C.

  4. Propensity towards cannibalism among Hypoaspis aculeifer and H. miles, two soil-dwelling predatory mite species.

    PubMed

    Berndt, Oliver; Meyhöfer, Rainer; Poehling, Hans-Michael

    2003-01-01

    In biological control programmes, the two predatory soil mites Hypoaspis aculeifer and H. miles are often applied against soil-borne pests like mushroom flies, springtails and mites. Although the mites show high consumption rates on varying prey types in Petri dish experiments and in greenhouses, their overall efficiency is sometimes limited. We hypothesized that intraspecific interactions, like cannibalism, could contribute to this decreased competence. Therefore, experiments were conducted to show the propensity of H. aculeifer and H. miles to cannibalise. Adult mites and nymphs were introduced as predators with conspecific eggs, larvae, nymphs, adult females or males as prey and the number of killed individuals was recorded. Additionally, the oviposition rate on conspecific prey was quantified and the correlation with the number of prey consumed was calculated to assess the influence of cannibalism on egg production. The results illustrate that cannibalism occurs infrequently in both Hypoaspis spp., the only exception being H. aculeifer nymphs, which cannibalised one conspecific egg per day. Moreover, cannibalism never occurred in the presence of alternative prey. Oviposition rate decreased during the experiment in both species but it was positively correlated with the cannibalism rate only for H. aculeifer. The benefit of cannibalism for populations of H. aculeifer and H. miles is discussed.

  5. National Emissions Inventory Vehicle Miles Traveled, U.S., 2014, EPA/OAR/OAQPS/AQAD

    EPA Pesticide Factsheets

    This web service contains layers that depict gridded Vehicle Miles Traveled (VMT) for 2014 from the National Emission Inventory (NEI).The default 2014 National Emissions Inventory (NEI) vehicle miles traveled (VMT) data are developed primarily from information provided by the Federal Highway Administration (FHWA), along with the FHWA??s published Highway Statistics 2014, data from the Bureau of Census, and information provided by the US Environmental Protection Agency (EPA). This 2014 full VMT database was developed to provide default VMT at the county, road type, and vehicle type level of detail, to be used in the 2014 NEI in areas for which no state or local agency provided VMT data. The road types included were the 12 Highway Performance Monitoring System (HPMS) functional roadway types while the vehicle types used were the six MOVES HPMS vehicle types , for a total of 72 records per county. To be compatible with MOVES inputs and for easy import into the MOVES HPMSVtypeYear table, the data were also provided at the level of county and HPMSVtypeID. In both cases, the VMT data provided are annual data in units of millions of vehicle miles.The 2014 VMT database was developed using data supplied directly by FHWA and as well as publicly available data from the 2014 version of FHWA??s Highway Statistics data series (http://www.fhwa.dot.gov/policyinformation/statistics/2014/). The FHWA data sets that were provided include a subset of fields from the 2014 HPMS

  6. Four Mile Creek semi-annual sampling report, January 1993 sampling event

    SciTech Connect

    Not Available

    1993-05-01

    From 1955 to 1988 low-level radioactive wastewater generated by chemical separation processes within the General Separations Area (GSA) was discharged to seepage basins in the F and H Areas of the Savannah River Site (SRS). These basins were designed to permit the infiltration of the process wastewaters. As wastewater percolated downward through the basins, chemical and radioactive constituents were retained or sequestered in the subsoils. An extensive study aimed at characterizing the groundwater seeping into Four Mile Creek and its associated seepline was conducted in 1988 and 1989 (Haselow et al. 1990). Results of this study suggested that contaminants leaching from the F and H Area seepage basins were impacting the Four Mile Creek wetland system. The seepage basins were closed in 1988 and capped and sealed in 1990. This effectively eliminated the source of the contaminants and the hydraulic head driving the migration of contaminants from the basins. It has been hypothesized that, after the elimination of the source and head, annual rainfall amounts would be sufficient to dilute and flush out contaminants remaining in the subsoils and groundwaters beneath the basins. Westinghouse Savannah River Company has designed a semi-annual sampling and analytical program for the Four Mile Creek (FMC) seepline and stream water to test the hypothesis. This report summarizes field monitoring activities from January 25, 1993 to February 4, 1993.

  7. Geology of the Shinarump No. 1 uranium mine, Seven Mile Canyon area, Grand County, Utah

    USGS Publications Warehouse

    Finch, Warren Irvin

    1954-01-01

    The geology of the Shinarump No. 1 uranium mine, located about 12 miles northwest of Moab, Utah, in the Seven Mile Canyon area, Grand County, Utah, was studied to determine the habits, ore controls, and possible origin of the deposit. Rocks of Permian, Triassic, and Jurassic age crop out in the area mapped, and uranium deposits are found in three zones in the lower 25 feet of the Chinle formation of Late Triassic age. The Shinarump No. 1 mine, which is in the lowermost zone, is located on the west flank of the Moab anticline near the Moab fault. The Shinarump No. 1 uranium deposit consists of discontinuous lenticular layers of mineralized rock, irregular in outline, that, in general, follow the bedding. Ore minerals, mainly uraninite, impregnate the rock. High-grade ore seams of uraninite and chalcocite occur along bedding planes. Uraninite formed later than, or simultaneous with, most sulfides, and the chalcocite may be of two ages, with some being later than uraninite. Uraninite and chalcocite are concentrated in the more poorly sorted parts of siltstones. In the Seven Mile Canyon area guides to ore inferred from the study of the Shinarump No. 1 deposit are the presence of bleached siltstone, carbonaceous matter, and copper sulfides. Results of spectrographic analysis indicate that the mineralizing solutions contained important amounts of barium, vanadium, uranium, and copper, as well as lesser amounts of strontium, chromium, boron, yttrium, lead, and zinc. The origin of the Shinarump No. 1 deposit is thought to be hydrothermal.

  8. Conflict resolution.

    PubMed

    Levin, Roger

    2006-03-01

    The sooner conflict is identified and confronted, the more quickly it can be resolved (and the sooner, the better). When this is accomplished calmly and objectively, many areas of conflict will be eliminated. Addressing conflict as it arises also sends a clear message to the team that the practice seeks resolution, not punishment or negative consequences. In addition, the dentist and the office manager need to lead by example by avoiding gossip and encouraging open communication. The goal is to go from a parent-child relationship with the dental team to an adult-adult relationship using this series of managerial conflict resolution steps.

  9. Structure and function of beta -1,4-galactosyltransferase.

    PubMed

    Qasba, Pradman K; Ramakrishnan, Boopathy; Boeggeman, Elizabeth

    2008-04-01

    Beta-1,4-galactosylransferase (beta4Gal-T1) participates in the synthesis of Galbeta1-4-GlcNAc-disaccharide unit of glycoconjugates. It is a trans-Golgi glycosyltransferase (Glyco-T) with a type II membrane protein topology, a short N-terminal cytoplasmic domain, a membrane-spanning region, as well as a stem and a C-terminal catalytic domain facing the trans-Golgi-lumen. Its hydrophobic membrane-spanning region, like that of other Glyco-T, has a shorter length compared to plasma membrane proteins, an important feature for its retention in the trans-Golgi. The catalytic domain has two flexible loops, a long and a small one. The primary metal binding site is located at the N-terminal hinge region of the long flexible loop. Upon binding of metal ion and sugar-nucleotide, the flexible loops undergo a marked conformational change, from an open to a closed conformation. Conformational change simultaneously creates at the C-terminal region of the flexible loop an oligosaccharide acceptor binding site that did not exist before. The loop acts as a lid covering the bound donor substrate. After completion of the transfer of the glycosyl unit to the acceptor, the saccharide product is ejected; the loop reverts to its native conformation to release the remaining nucleotide moiety. The conformational change in beta4Gal-T1 also creates the binding site for a mammary gland-specific protein, alpha-lactalbumin (LA), which changes the acceptor specificity of the enzyme toward glucose to synthesize lactose during lactation. The specificity of the sugar donor is generally determined by a few residues in the sugar-nucleotide binding pocket of Glyco-T, conserved among the family members from different species. Mutation of these residues has allowed us to design new and novel glycosyltransferases, with broader or requisite donor and acceptor specificities, and to synthesize specific complex carbohydrates as well as specific inhibitors for these enzymes.

  10. NCAI Resolutions

    ERIC Educational Resources Information Center

    American Indian Journal of the Institute for the Development of Indian Law, 1977

    1977-01-01

    Five Major Policy Resolutions were adopted, without objection, at the 33rd Annual Convention of the National Congress of American Indians (NCAI) held in Salt Lake City, Utah, in October 1976. The issues involved were: Treaties and Trust Responsibilities, Tribal Government, Jurisdiction, Federal Administration and Structure of Indian Affairs, and…

  11. Atmospheric photochemical degradation of 1,4-unsaturated dicarbonyls

    SciTech Connect

    Liu, X.; Jeffries, H.E.; Sexton, K.G.

    1999-12-01

    To better understand fates of aromatics hydrocarbon species in the atmosphere, the authors have investigated the transformation chemistry of butenedial (CHOCH{double{underscore}bond}CHCHO), 4-oxo-2-pentenal (CH{sub 3}COCH{double{underscore}bond}CHCHO), and 3-hexene-2, 5-dione (CH{sub 3}COCH{double{underscore}bond}CHCOCH{sub 3}). These 1,4-unsaturated dicarbonyls are known to be products of aromatic photochemical oxidation. Both hydroxyl radical (OH) and ozone (O{sub 3}) initiated smog chamber experiments under atmospheric conditions were conducted in the University of North Carolina outdoor smog chamber. Carbonyl intermediates and products were measured using the O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine derivatization method followed by gas chromatography/ion trap mass spectrometry analysis. Carbonyl products detected and identified by comparison with standards in the OH-initiated photooxidation of butenedial include formaldehyde, acrolein, glycolaldehyde, glyoxal, and malonaldehyde (CHOCH{sub 2}CHO). For 4-oxo-2-pentenal, the carbonyl products were formaldehyde, methyl vinyl ketone, glycolaldehyde, hydroxyacetone, glyoxal, methylglyoxal, and malonaldehyde. for 3-hexene-2,5-dione the products were formaldehyde, acetaldehyde, acetone, hydroxyacetone, and methylglyoxal. Carbonyl products detected in the P{sub 3}-initiated experiments with cyclohexane as the OH scavenger were formaldehyde and glyoxal in butenedial; formaldehyde, glyoxal, methyl-glyoxal, and malonaldehyde in 4-oxo-2-pentenal; and formaldehyde and methylglyoxal in 3-hexene-2,5-dione.

  12. Orbital forcing of climate 1.4 billion years ago.

    PubMed

    Zhang, Shuichang; Wang, Xiaomei; Hammarlund, Emma U; Wang, Huajian; Costa, M Mafalda; Bjerrum, Christian J; Connelly, James N; Zhang, Baomin; Bian, Lizeng; Canfield, Donald E

    2015-03-24

    Fluctuating climate is a hallmark of Earth. As one transcends deep into Earth time, however, both the evidence for and the causes of climate change become difficult to establish. We report geochemical and sedimentological evidence for repeated, short-term climate fluctuations from the exceptionally well-preserved ∼1.4-billion-year-old Xiamaling Formation of the North China Craton. We observe two patterns of climate fluctuations: On long time scales, over what amounts to tens of millions of years, sediments of the Xiamaling Formation record changes in geochemistry consistent with long-term changes in the location of the Xiamaling relative to the position of the Intertropical Convergence Zone. On shorter time scales, and within a precisely calibrated stratigraphic framework, cyclicity in sediment geochemical dynamics is consistent with orbital control. In particular, sediment geochemical fluctuations reflect what appear to be orbitally forced changes in wind patterns and ocean circulation as they influenced rates of organic carbon flux, trace metal accumulation, and the source of detrital particles to the sediment.

  13. A mechanism for 1,4-Benzoquinone-induced genotoxicity

    PubMed Central

    Son, Mi Young; Deng, Chu-Xia; Hoeijmarkers, Jan H.; Rebel, Vivienne I.; Hasty, Paul

    2016-01-01

    Benzene is a common environmental toxin and its metabolite, 1-4-Benzoquinone (BQ) causes hematopoietic cancers like myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). BQ has not been comprehensively assessed for its impact on genome maintenance, limiting our understanding of the true health risks associated with benzene exposure and our ability to identify people with increased sensitivity to this genotoxin. Here we analyze the impact BQ exposure has on wild type and DNA repair-defective mouse embryonic stem (ES) cells and wild type human cells. We find that double strand break (DSB) repair and replication fork maintenance pathways including homologous recombination (HR) and Fanconi anemia (FA) suppress BQ toxicity. BQ-induced damage efficiently stalls replication forks, yet poorly induces ATR/DNA-PKCS responses. Furthermore, the pattern of BQ-induced γH2AX and 53BP1foci is consistent with the formation of poly(ADP-ribose) polymerase 1 (PARP1)-stabilized regressed replication forks. At a biochemical level, BQ inhibited topoisomerase 1 (topo1)-mediated DNA ligation and nicking in vitro; thus providing mechanism for the cellular phenotype. These data are consistent with a model that proposes BQ interferes with type I topoisomerase's ability to maintain replication fork restart and progression leading to chromosomal instability that has the potential to cause hematopoietic cancers like MDS and AML. PMID:27340773

  14. Nucleophilic 1,4-additions for natural product discovery.

    PubMed

    Cox, Courtney L; Tietz, Jonathan I; Sokolowski, Karol; Melby, Joel O; Doroghazi, James R; Mitchell, Douglas A

    2014-09-19

    Natural products remain an important source of drug candidates, but the difficulties inherent to traditional isolation, coupled with unacceptably high rates of compound rediscovery, limit the pace of natural product detection. Here we describe a reactivity-based screening method to rapidly identify exported bacterial metabolites that contain dehydrated amino acids (i.e., carbonyl- or imine-activated alkenes), a common motif in several classes of natural products. Our strategy entails the use of a commercially available thiol, dithiothreitol, for the covalent labeling of activated alkenes by nucleophilic 1,4-addition. Modification is easily discerned by comparing mass spectra of reacted and unreacted cell surface extracts. When combined with bioinformatic analysis of putative natural product gene clusters, targeted screening and isolation can be performed on a prioritized list of strains. Moreover, known compounds are easily dereplicated, effectively eliminating superfluous isolation and characterization. As a proof of principle, this labeling method was used to identify known natural products belonging to the thiopeptide, lanthipeptide, and linaridin classes. Further, upon screening a panel of only 23 actinomycetes, we discovered and characterized a novel thiopeptide antibiotic, cyclothiazomycin C.

  15. Metabolism of [(1)(4)C]prometryn in rats.

    PubMed

    Maynard, M S; Brumback, D; Itterly, W; Capps, T; Rose, R

    1999-09-01

    [(1)(4)C]Prometryn, 2, 4-bis(isopropylamino)-6-(methylthio)-s-triazine, was orally administered to male and female rats at approximately 0.5 and 500 mg/kg; daily urine and feces were collected. After 3 or 7 days rats were sacrificed, and blood and selected tissues were isolated. The urine and feces extracts were characterized for metabolite similarity as well as for metabolite identification. Over 30 metabolites were observed, and of these, 28 were identified mostly by mass spectrometry and/or cochromatography with available reference standards. The metabolism of prometryn was shown to occur by N-demethylation, S-oxidation, S-S dimerization, OH substitution for NH(2) and SCH(3), and conjugation with glutathione or glucuronic acid. Rat liver microsomal incubations of prometryn were conducted and compared to the in vivo metabolism. Both in vivo and in vitro phase I metabolisms of prometryn were similar, with S-oxidation and N-dealkylation predominating. The involvement of cytochrome P-450 and flavin-containing monooxidase in the in vitro metabolism of prometryn was investigated.

  16. Phytoremediation of 1,4-dioxane-containing recovered groundwater.

    PubMed

    Ferro, Ari M; Kennedy, Jean; LaRue, James C

    2013-01-01

    The results of a pilot-scale phytoremediation study are reported in this paper. Small plots of trees established on a closed municipal waste landfill site were irrigated with recovered groundwater containing 1,4-dioxane (dioxane) and other volatile organic compounds (VOCs). The plots were managed to minimize the leaching of irrigation water, and leaching was quantified by the use of bromide tracer. Results indicated that the dioxane (2.5 microg/L) was effectively removed, probably via phytovolatilization, and that a full-scale phytoremediation system could be used. A system is now in place at the site in which the recovered groundwater can be treated using two different approaches. A physical treatment system (PTS) will be used during the winter months, and a 12 ha phytoremediation system (stands of coniferous trees) will be used during the growing season. The PTS removes VOCs using an air-stripper, and destroys dioxane using a photo-catalytic oxidation process. Treated water will be routed to the local sewer system. The phytoremediation system, located on the landfill, will be irrigated with effluent from the PTS air-stripper containing dioxane. Seasonal use of the phytoremediation system will reduce reliance on the photo-catalytic oxidation process that is extremely energy consumptive and expensive to operate.

  17. Orbital forcing of climate 1.4 billion years ago

    PubMed Central

    Zhang, Shuichang; Wang, Xiaomei; Hammarlund, Emma U.; Wang, Huajian; Costa, M. Mafalda; Bjerrum, Christian J.; Connelly, James N.; Zhang, Baomin; Bian, Lizeng; Canfield, Donald E.

    2015-01-01

    Fluctuating climate is a hallmark of Earth. As one transcends deep into Earth time, however, both the evidence for and the causes of climate change become difficult to establish. We report geochemical and sedimentological evidence for repeated, short-term climate fluctuations from the exceptionally well-preserved ∼1.4-billion-year-old Xiamaling Formation of the North China Craton. We observe two patterns of climate fluctuations: On long time scales, over what amounts to tens of millions of years, sediments of the Xiamaling Formation record changes in geochemistry consistent with long-term changes in the location of the Xiamaling relative to the position of the Intertropical Convergence Zone. On shorter time scales, and within a precisely calibrated stratigraphic framework, cyclicity in sediment geochemical dynamics is consistent with orbital control. In particular, sediment geochemical fluctuations reflect what appear to be orbitally forced changes in wind patterns and ocean circulation as they influenced rates of organic carbon flux, trace metal accumulation, and the source of detrital particles to the sediment. PMID:25775605

  18. Solar wind halo electrons from 1-4 AU

    NASA Technical Reports Server (NTRS)

    Mccomas, D. J.; Bame, S. J.; Feldman, W. C.; Gosling, J. T.; Phillips, J. L.

    1992-01-01

    Observations from the Ulysses solar wind electron spectrometer are used to make a first examination of the evolution of the solar wind suprathermal or halo electron population as a function of heliocentric distance beyond 1 AU. As the core population cools with increasing heliocentric distance, no gap is formed between the core and halo populations. Rather, the halo electrons extend to increasingly lower energies. As predicted previously on theoretical grounds, the ratio of the core electron temperature to the low energy cutoff of the halo population appears to be roughly constant with a value of about 7.5. The total integrated heat flux drops rapidly with increasing heliocentric distance; a best fit power law of R exp -2.36 is found. In addition, it is found that the ratio of the halo to core densities is roughly constant over heliocentric distance with the halo representing 4 percent of the total electron distribution. These results suggest that the halo population may not consist of truly noninteractive test particles over the heliocentric range of 1-4 AU.

  19. Share of mass transit miles traveled and reduced motor vehicle fatalities in major cities of the United States.

    PubMed

    Stimpson, Jim P; Wilson, Fernando A; Araz, Ozgur M; Pagan, Jose A

    2014-12-01

    The USA leads the developed world in motor vehicle fatalities, presenting a critical public health threat. We examined whether an increasing share of mass transit use, relative to vehicle miles traveled on public roads, was associated with reduced motor vehicle fatalities. We used annual city-level data for the USA from 1982-2010 provided by the Fatality Accident Reporting System, the Texas A&M Transportation Institute, the Census Bureau, and the National Oceanic and Atmospheric Administration to estimate a structural equation model of the factors associated with mass transit miles and motor vehicle fatalities. The final analytic data included 2,900 observations from 100 cities over 29 years. After accounting for climate, year, and the economic costs of driving, an increasing share of mass transit miles traveled per capita was associated with reduced motor vehicle fatalities. The costs of congestion to the average commuter and gas prices were positively associated with increasing the share of mass transit miles traveled. The economic costs of driving increased over time, while both the fatality rate and the share of mass transit miles traveled decreased over time. Increasing the share of mass transit miles traveled may be associated with fewer motor vehicle miles traveled. Increasing mass transit uptake may be an effective public health intervention to reduce motor vehicle fatalities in cities.

  20. Europa Ice Cliffs-High Resolution

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This view of the Conamara Chaos region on Jupiter's moon Europa shows cliffs along the edges of high-standing ice plates. The washboard texture of the older terrain has been broken into plates which are separated by material with a jumbled texture. The cliffs themselves are rough and broadly scalloped, and smooth debris shed from the cliff faces is piled along the base. For scale, the height of the cliffs and size of the scalloped indentations are comparable to the famous cliff face of Mount Rushmore in South Dakota.

    This image was taken on December 16, 1997 at a range of 900 kilometers (540 miles) by the solid state imaging system (camera) on NASA's Galileo spacecraft. North is to the top right of the picture, and the sun illuminates the surface from the east. This image, centered at approximately 8 degrees north latitude and 273 degrees west longitude, covers an area approximately 1.5 kilometers by 4 kilometers (0.9 miles by 2.4 miles). The resolution is 9 meters (30 feet) per picture element.

    The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

    This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://www.jpl.nasa.gov/ galileo.

  1. DOT++: the Dutch Open Telescope with 1.4-m aperture

    NASA Astrophysics Data System (ADS)

    Bettonvil, Felix C.; Hammerschlag, Robert H.; Sütterlin, Peter; Rutten, Robert J.; Jägers, Aswin P.; Snik, Frans

    2004-10-01

    The Dutch Open Telescope (DOT; http://dot.astro.uu.nl) on La Palma is a revolutionary open solar telescope, on an excellent site, on top of a transparent steel tower, and uses natural air flow to minimize local seeing. The aim is long-duration high-resolution imaging with a multi-wavelength camera system. In order to achieve this, the DOT is equipped with a diffraction limited imaging system and uses the speckle reconstruction technique for removing the remaining atmospheric turbulence. The DOT optical system is simple and consists currently of a 0.45m/F4.44 parabolic mirror and a 10x enlargement lens system. We present our plans to increase the aperture of the DOT from 0.45m to 1.4m. The mirror support and telescope top shall be redesigned, but telescope, tower, multi-wavelength camera system and speckle system remain intact. The new optical design permits user selectable choice between angular resolution and field size, as well as transversal pupil shift introducing the possibility to use obstruction free apertures up to 65cm. The design will include a low order AO system, which improves the speckle S/N substantially during moderate seeing conditions.

  2. Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System.

    PubMed

    Moothanchery, Mohesh; Pramanik, Manojit

    2017-02-12

    Photoacoustic microscopy (PAM) is a scalable bioimaging modality; one can choose low acoustic resolution with deep penetration depth or high optical resolution with shallow imaging depth. High spatial resolution and deep penetration depth is rather difficult to achieve using a single system. Here we report a switchable acoustic resolution and optical resolution photoacoustic microscopy (AR-OR-PAM) system in a single imaging system capable of both high resolution and low resolution on the same sample. Lateral resolution of 4.2 µm (with ~1.4 mm imaging depth) and lateral resolution of 45 μm (with ~7.6 mm imaging depth) was successfully demonstrated using a switchable system. In vivo blood vasculature imaging was also performed for its biological application.

  3. Performance Characterization of a Switchable Acoustic Resolution and Optical Resolution Photoacoustic Microscopy System

    PubMed Central

    Moothanchery, Mohesh; Pramanik, Manojit

    2017-01-01

    Photoacoustic microscopy (PAM) is a scalable bioimaging modality; one can choose low acoustic resolution with deep penetration depth or high optical resolution with shallow imaging depth. High spatial resolution and deep penetration depth is rather difficult to achieve using a single system. Here we report a switchable acoustic resolution and optical resolution photoacoustic microscopy (AR-OR-PAM) system in a single imaging system capable of both high resolution and low resolution on the same sample. Lateral resolution of 4.2 µm (with ~1.4 mm imaging depth) and lateral resolution of 45 μm (with ~7.6 mm imaging depth) was successfully demonstrated using a switchable system. In vivo blood vasculature imaging was also performed for its biological application. PMID:28208676

  4. Analysis of performance and age of the fastest 100-mile ultra-marathoners worldwide

    PubMed Central

    Rüst, Christoph Alexander; Knechtle, Beat; Rosemann, Thomas; Lepers, Romuald

    2013-01-01

    OBJECTIVES: The performance and age of peak ultra-endurance performance have been investigated in single races and single race series but not using worldwide participation data. The purpose of this study was to examine the changes in running performance and the age of peak running performance of the best 100-mile ultra-marathoners worldwide. METHOD: The race times and ages of the annual ten fastest women and men were analyzed among a total of 35,956 finishes (6,862 for women and 29,094 for men) competing between 1998 and 2011 in 100-mile ultra-marathons. RESULTS: The annual top ten performances improved by 13.7% from 1,132±61.8 min in 1998 to 977.6±77.1 min in 2011 for women and by 14.5% from 959.2±36.4 min in 1998 to 820.6±25.7 min in 2011 for men. The mean ages of the annual top ten fastest runners were 39.2±6.2 years for women and 37.2±6.1 years for men. The age of peak running performance was not different between women and men (p>0.05) and showed no changes across the years. CONCLUSION: These findings indicated that the fastest female and male 100-mile ultra-marathoners improved their race time by ∼14% across the 1998–2011 period at an age when they had to be classified as master athletes. Future studies should analyze longer running distances (>200 km) to investigate whether the age of peak performance increases with increased distance in ultra-marathon running. PMID:23778421

  5. Geology of the Shinarump No. 1 uranium mine, Seven Mile Canyon area, Grand County, Utah

    USGS Publications Warehouse

    Finch, Warren Irvin

    1953-01-01

    The Shinarump No. 1 uranium mine is located about 12 miles northwest of Moab, Utah, in the Seven Mile Canyon area, Grand County, Utah. A study was made of the geology of the Shinarump No. 1 mine in order to determine the habits, ore controls, and possible origin of the deposit. Rocks of Permain, Triassic, and Jurassic age crop out in the area mapped. Uranium deposits are found in three zones in the lower 25 feet of the Upper Triassic Chinle formation. The Shinarump No. 1 mine, which is in the lowermost zone, is located on the west flank of the Moab anticline near the Moab fault. The Shinarump No. 1 uranium deposit consists of discontinuous lenticular layers of mineralized rock, irregular in outline, that, in general, follow the bedding. Ore minerals, mainly uranite, impregnate the rock. High-grade seams of uranite and chalcocite occur along bedding planes. Formation of unraninite is later than or simultaneous with most sulfides. Chalcocite may be of two ages, with some being later than uraninite. Uraninite and chalcocite are concentrated in the poorer sorted parts of siltstones. Guides to ore in the Seven Mile Canyon area inferred from the study of the Shinarump No. 1 deposit are the presence of bleached siltstone, copper sulfides, and carbonaceous matter. Results of spectrographic analysis indicated that the mineralizing solutions contained important amounts of barium, vanadium, uranium, and copper as well as lesser amounts of strontium, chromium, boron, yttrium, lead, and zinc. The origin of the Shinarump No. 1 deposit is thought to be hydrothermal, dated as later or early.

  6. Flood-inundation maps for a 15-mile reach of the Kalamazoo River from Marshall to Battle Creek, Michigan, 2010

    USGS Publications Warehouse

    Hoard, C.J.; Fowler, K.K.; Kim, M.H.; Menke, C.D.; Morlock, S.E.; Peppler, M.C.; Rachol, C.M.; Whitehead, M.T.

    2010-01-01

    Digital flood-inundation maps for a 15-mile reach of the Kalamazoo River from Marshall to Battle Creek, Michigan, were created by the U.S. Geological Survey (USGS) in cooperation with the U.S. Environmental Protection Agency to help guide remediation efforts following a crude-oil spill on July 25, 2010. The spill happened on Talmadge Creek, a tributary of the Kalamazoo River near Marshall, during a flood. The floodwaters transported the spilled oil down the Kalamazoo River and deposited oil in impoundments and on the surfaces of islands and flood plains. Six flood-inundation maps were constructed corresponding to the flood stage (884.09 feet) coincident with the oil spill on July 25, 2010, as well as for floods with annual exceedance probabilities of 0.2, 1, 2, 4, and 10 percent. Streamflow at the USGS streamgage at Marshall, Michigan (USGS site ID 04103500), was used to calculate the flood probabilities. From August 13 to 18, 2010, 35 channel cross sections, 17 bridges and 1 dam were surveyed. These data were used to construct a water-surface profile for the July 25, 2010, flood by use of a one-dimensional step-backwater model. The calibrated model was used to estimate water-surface profiles for other flood probabilities. The resulting six flood-inundation maps were created with a geographic information system by combining flood profiles with a 1.2-foot vertical and 10-foot horizontal resolution digital elevation model derived from Light Detection and Ranging data.

  7. Compilation of Earthquakes from 1850-2007 within 200 miles of the Idaho National Laboratory

    SciTech Connect

    N. Seth Carpenter

    2010-07-01

    An updated earthquake compilation was created for the years 1850 through 2007 within 200 miles of the Idaho National Laboratory. To generate this compilation, earthquake catalogs were collected from several contributing sources and searched for redundant events using the search criteria established for this effort. For all sets of duplicate events, a preferred event was selected, largely based on epicenter-network proximity. All unique magnitude information for each event was added to the preferred event records and these records were used to create the compilation referred to as “INL1850-2007”.

  8. On Some Mile-Stones in Scientific Life of Professor Alexander N. Guz*

    NASA Astrophysics Data System (ADS)

    Rushchitsky, J. J.

    2013-07-01

    This article is prepared on the occasion of awarding Professor A.N. Guz the ICCES Lifetime Achievement Medal and was read as a lecture at the International Conference on Computational and Experimental Engineering and Sciences (ICCES-12), Greece, Crete, April 30-May 4, 2012. Four important mile-stones in the scientific life of A. N. Guz are shown and discussed: defense of doctor of sciences dissertation, forming of new scientific areas and scientific school, directorship at the S. P. Timoshenko Institute of Mechanics, preparation of many monographs, which can be classified as the first ones in the world's scientific literature

  9. Two-Dimensional (2-D) Acoustic Fish Tracking at River Mile 85, Sacramento River, California

    DTIC Science & Technology

    2013-06-01

    7 ii Abstract Fish behavior in response to levee repairs at River Mile 85.6 of the Sacramento River was monitored using 60 VR2W 180-kHz and 45...arrays of VR2W 69-kHz receivers were installed in the river adjacent to levee repair sites and natural areas. This initial effort at 2-D tracking...a levee repair site was located on the outside of a river bend. The site was located at RM 85, just south of Knights Landing, California. The study

  10. Safely Transporting the assembled EUSO-SPB instrument 1000 miles for field testing

    NASA Astrophysics Data System (ADS)

    Cummings, Austin; Gregg, Rachael; Polonsky, Zach

    2017-01-01

    The EUSO-SPB instrument assembled and tested at Colorado School of Mines and then transported in this state to the Telescope Array site in Delta Utah for field tests. 6 hours after arrival the instrument recorded first light from a laser 20 km distant. We describe the structures and methods that we developed drive this instrument to the test site. The vibration data collected during the 1000 mile round trip and the lessons learned will also be presented. In our experience, there is relatively little quantitative information available about this type of critical operation.

  11. 78 FR 22347 - GPU Nuclear Inc., Three Mile Island Nuclear Power Station, Unit 2, Exemption From Certain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION GPU Nuclear Inc., Three Mile Island Nuclear Power Station, Unit 2, Exemption From Certain Security Requirements AGENCY: Nuclear Regulatory Commission. ACTION: Exemption. FOR FURTHER INFORMATION CONTACT: John...

  12. Evidence of 1,4-dioxane attenuation at groundwater sites contaminated with chlorinated solvents and 1,4-dioxane.

    PubMed

    Adamson, David T; Anderson, R Hunter; Mahendra, Shaily; Newell, Charles J

    2015-06-02

    There is a critical need to develop appropriate management strategies for 1,4-dioxane (dioxane) due to its widespread occurrence and perceived recalcitrance at groundwater sites where chlorinated solvents are present. A comprehensive evaluation of California state (GeoTracker) and Air Force monitoring records was used to provide significant evidence of dioxane attenuation at field sites. Temporal changes in the site-wide maximum concentrations were used to estimate source attenuation rates at the GeoTracker sites (median length of monitoring period = 6.8 years). While attenuation could not be established at all sites, statistically significant positive attenuation rates were confirmed at 22 sites. At sites where dioxane and chlorinated solvents were present, the median value of all statistically significant dioxane source attenuation rates (equivalent half-life = 31 months; n = 34) was lower than 1,1,1-trichloroethane (TCA) but similar to 1,1-dichloroethene (1,1-DCE) and trichloroethene (TCE). Dioxane attenuation rates were positively correlated with rates for 1,1-DCE and TCE but not TCA. At this set of sites, there was little evidence that chlorinated solvent remedial efforts (e.g., chemical oxidation, enhanced bioremediation) impacted dioxane attenuation. Attenuation rates based on well-specific records from the Air Force data set confirmed significant dioxane attenuation (131 out of 441 wells) at a similar frequency and extent (median equivalent half-life = 48 months) as observed at the California sites. Linear discriminant analysis established a positive correlation between dioxane attenuation and increasing concentrations of dissolved oxygen, while the same analysis found a negative correlation with metals and CVOC concentrations. The magnitude and prevalence of dioxane attenuation documented here suggest that natural attenuation may be used to manage some but not necessarily all dioxane-impacted sites.

  13. Modulatory effects of plant polyphenols on human multidrug resistance proteins 1, 4, and 5 (ABCC1, 4, and 5)

    PubMed Central

    Wu, Chung-Pu; Calcagno, Anna Maria; Hladky, Stephen B.; Ambudkar, Suresh V.; Barrand, Margery A.

    2005-01-01

    SUMMARY Plant flavonoids are polyphenolic compounds commonly found in vegetables, fruits and many food sources that form a significant portion of our diet. These compounds have been shown to interact with several ATP-Binding Cassette transporters that are linked with anticancer and antiviral drug resistance and as such, may be beneficial in modulating drug resistance. The present study investigates the interactions of six common polyphenols; quercetin, silymarin, resveratrol, naringenin, daidzein and hesperetin with the multidrug resistance associated proteins, MRP1, MRP4 and MRP5. At non-toxic concentrations, several of the polyphenols were able to modulate MRP1-, MRP4- and MRP5- mediated drug resistance though to varying extents. The polyphenols also reversed resistance to NSC251820, a compound that appears to be a good substrate for MRP4 as had been predicted by data mining studies. Furthermore, most of the polyphenols showed direct inhibition of MRP1-mediated [3H]-dinitrophenyl S-glutathione and MRP4-mediated [3H]-cGMP transport in inside-out vesicles prepared from human erythrocytes. Additionally, both quercetin and silymarin were found to inhibit MRP1-, MRP4-, and MRP5-mediated transport from intact cells with high affinity. They also had significant effects on ATPase activity of MRP1 and MRP4 without having any effect on [α-32P]8-azidoATP binding to these proteins. This suggests that these flavonoids most likely interact at the transporter’s substrate-binding sites. Collectively, these results suggest that dietary flavonoids such as quercetin and silymarin can modulate transport activities of MRP1, 4 and 5. Such interactions could influence bioavailability of anticancer and antiviral drugs in vivo and thus, should be considered for increasing efficacy in drug therapies. PMID:16156793

  14. Human responses to the threat of or exposure to ionizing radiation at Three Mile Island, Pennsylvania, and Goiania, Brazil.

    PubMed

    Collins, Daniel L

    2002-02-01

    The psychological stressors and their aftereffects associated with the Three Mile Island accident, the Goiania, Brazil, cesium-137 accident, and the Abadia, Brazil, storage location are summarized and compared. Cross-cultural comparisons of human responses to ionizing radiation are rare. A multidisciplinary methodological approach to examining the psychological responses to ionizing radiation is even more rare. The psychological, behavioral, neuroendocrine, and cardiovascular results are summarized for Three Mile Island, Goiania, and Abadia.

  15. Laboratory measurement verification of laser hazard analysis for miles weapon simulators used in force on force exercises.

    SciTech Connect

    Augustoni, Arnold L.

    2006-08-01

    Due to the change in the batteries used with the Small Arm Laser Transmitters (SALT) from 3-volts dc to 3.6-volts dc and changes to SNL MILES operating conditions, the associated laser hazards of these units required re-evaluation to ensure that the hazard classification of the laser emitters had not changed as well. The output laser emissions of the SNL MILES, weapon simulators and empire guns, used in Force-On-Force (FOF) training exercises, was measured in accordance to the ANSI Standard Z136.4-2005, ''Recommended Practice for Laser Safety Measurements for Hazard Evaluation''. The laser hazard class was evaluated in accordance with the ANSI Standard Z136.1-2000, ''Safe Use of Lasers'', using ''worst'' case conditions associated with these MILES units. Laser safety assessment was conducted in accordance with the ANSI Standard Z136.6-2005, ''Safe Use of Lasers Outdoors''. The laser hazard evaluation of these MILES laser emitters was compared to and supersedes SAND Report SAND2002-0246, ''Laser Safety Evaluation of the MILES and Mini MILES Laser Emitting Components'', which used ''actual'' operating conditions of the laser emitters at the time of its issuance.

  16. LIP: The Livermore Interpolation Package, Version 1.4

    SciTech Connect

    Fritsch, F N

    2011-07-06

    or invert the interpolant at an arbitrary number of points. The first section of this report describes the overall design of the package, including both forward and inverse interpolation. Sections 2-6 describe each interpolation method in detail. The software that implements this design is summarized function-by-function in Section 7. For a complete example of package usage, refer to Section 8. The report concludes with a few brief notes on possible software enhancements. For guidance on adding other functional forms to LIP, refer to Appendix B. The reader who is primarily interested in using LIP to solve a problem should skim Section 1, then skip to Sections 7.1-4. Finally, jump ahead to Section 8 and study the example. The remaining sections can be referred to in case more details are desired. Changes since version 1.1 of this document include the new Section 3.2.1 that discusses derivative estimation and new Section 6 that discusses the birational interpolation method. Section numbers following the latter have been modified accordingly.

  17. 75 FR 34045 - Sodium 1,4-Dialkyl Sulfosuccinates; Exemption from the Requirement of a Tolerance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... AGENCY 40 CFR Part 180 Sodium 1,4-Dialkyl Sulfosuccinates; Exemption from the Requirement of a Tolerance... an exemption from the requirement of a tolerance for residues of sodium 1,4-dialkyl sulfosuccinates including sodium 1,4-dihexyl sulfosuccinate (CAS Reg. No. 3006-15-3); sodium 1,4-diisobutyl...

  18. Addition polymers from 1,4,5,8-tetrahydro-1,4;5,8-diepoxyanthracene and Bis-dienes. 2: Evidence for thermal dehydration occurring in the cure process

    NASA Technical Reports Server (NTRS)

    Meador, Mary Ann B.; Olshavsky, Michael A.; Meador, Michael A.; Ahn, Myong-Ku

    1988-01-01

    Diels-Alder cycloaddition copolymers from 1,4,5,8-tetrahydro-1,4;5,8-diepoxyanthracene and anthracene end-capped polyimide oligomers appear, by thermogravimetric analysis (TGA), to undergo dehydration at elevated temperatures. This would produce thermally stable pentiptycene units along the polymer backbone, and render the polymers incapable of unzipping through a retro-Diels-Alder pathway. High resolution solid 13C nuclear magnetic resonance (NMR) of one formulation of the polymer system before and after heating at elevated temperatures, shows this to indeed be the case. NMR spectra of solid samples of the polymer before and after heating correlated well with those of the parent pentiptycene model compound before and after acid-catalyzed dehydration. Isothermal gravimetric analyses and viscosities of the polymer before and after heat treatment support dehydration as a mechanism for the cure reaction.

  19. Cigarette smoking and the risk of adult leukemia: results from the Three Mile Island cohort study.

    PubMed

    Xu, Xiaohui; Talbott, Evelyn O; Zborowski, Jeanne V; Rager, Judith R

    2007-01-01

    Smoking is an unconfirmed risk factor for the development of leukemia. The authors examined the potential link using data from the Three Mile Island cohort for the period 1979-1995. Eligible for analysis were 24,539 individuals aged 14 years or older who were followed up over 16 years from the Three Mile Island cohort. The authors identified all incident leukemia cases through the Pennsylvania Department of Health Cancer Registry. They used the Cox proportional hazards model to evaluate the relationships and observed 42 incident leukemia cases, including 15 acute myeloid leukemia (AML) cases, in the cohort. After controlling for other confounding factors, the authors found current smoking to be associated with an increased risk of adult AML (relative risk = 3.47; 95% confidence interval = 1.002-11.99). The authors also observed a marginally significant linear trend of risk of AML associated with the number of years smoked (p = .06). The results from this study suggested that cigarette smoking was associated with an increased risk of adult AML. Further investigation is required to confirm these findings.

  20. MILES extended: Stellar population synthesis models from the optical to the infrared

    NASA Astrophysics Data System (ADS)

    Röck, B.; Vazdekis, A.; Ricciardelli, E.; Peletier, R. F.; Knapen, J. H.; Falcón-Barroso, J.

    2016-05-01

    We present the first single-burst stellar population models, which covers the optical and the infrared wavelength range between 3500 and 50 000 Å and which are exclusively based on empirical stellar spectra. To obtain these joint models, we combined the extended MILES models in the optical with our new infrared models that are based on the IRTF (Infrared Telescope Facility) library. The latter are available only for a limited range in terms of both age and metallicity. Our combined single-burst stellar population models were calculated for ages larger than 1 Gyr, for metallicities between [ Fe / H ] = - 0.40 and 0.26, for initial mass functions of various types and slopes, and on the basis of two different sets of isochrones. They are available to the scientific community on the MILES web page. We checked the internal consistency of our models and compared their colour predictions to those of other models that are available in the literature. Optical and near infrared colours that are measured from our models are found to reproduce the colours well that were observed for various samples of early-type galaxies. Our models will enable a detailed analysis of the stellar populations of observed galaxies.

  1. Spontaneous abortions after the Three Mile Island nuclear accident: a life table analysis

    SciTech Connect

    Goldhaber, M.K.; Staub, S.L.; Tokuhata, G.K.

    1983-07-01

    A study was conducted to determine whether the incidence of spontaneous abortion was greater than expected near the Three Mile Island (TMI) nuclear power plant during the months following the March 28, 1979 accident. All persons living within five miles of TMI were registered shortly after the accident, and information on pregnancy at the time of the accident was collected. After one year, all pregnancy cases were followed up and outcomes ascertained. Using the life table method, it was found that, given pregnancies after four completed weeks of gestation counting from the first day of the last menstrual period, the estimated incidence of spontaneous abortion (miscarriage before completion of 16 weeks of gestation) was 15.1 per cent for women pregnant at the time of the TMI accident. Combining spontaneous abortions and stillbirths (delivery of a dead fetus after 16 weeks of gestation), the estimated incidence was 16.1 per cent for pregnancies after four completed weeks of gestation. Both incidences are comparable to baseline studies of fetal loss.

  2. Lessons Learned from Three Mile Island Packaging, Transportation and Disposition that Apply to Fukushima Daiichi Recovery

    SciTech Connect

    Layne Pincock; Wendell Hintze; Dr. Koji Shirai

    2012-07-01

    Following the massive earthquake and resulting tsunami damage in March of 2011 at the Fukushima Daiichi nuclear power plant in Japan, interest was amplified for what was done for recovery at the Three Mile Island Unit 2 (TMI-2) in the United States following its meltdown in 1979. Many parallels could be drawn between to two accidents. This paper presents the results of research done into the TMI-2 recovery effort and its applicability to the Fukushima Daiichi cleanup. This research focused on three topics: packaging, transportation, and disposition. This research work was performed as a collaboration between Japan’s Central Research Institute of Electric Power Industry (CRIEPI) and the Idaho National Laboratory (INL). Hundreds of TMI-2 related documents were searched and pertinent information was gleaned from these documents. Other important information was also obtained by interviewing employees who were involved first hand in various aspects of the TMI-2 cleanup effort. This paper is organized into three main sections: (1) Transport from Three Mile Island to Central Facilities Area at INL, (2) Transport from INL Central Receiving Facility to INL Test Area North (TAN) and wet storage at TAN, and (3) Transport from TAN to INL Idaho Nuclear Technology and Engineering Center (INTEC) and Dry Storage at INTEC. Within each of these sections, lessons learned from performing recovery activities are presented and their applicability to the Fukushima Daiichi nuclear power plant cleanup are outlined.

  3. Construction of a 40-mile long roadside scale model of the solar system in northern Maine

    NASA Astrophysics Data System (ADS)

    McCartney, K.

    2001-05-01

    The Maine Solar System Model is currently under construction along Route 1 between Houlton and Presque Isle, in Aroostook County, northern Maine. The scale is 1:93,000,000, or 1 mile equals an astronomical unit. There is a 40 mile distance between the Sun (diameter 49.5 feet) and Pluto (diameter 1 inch). The model will include the Sun, nine planets and seven moons, with diameters and distances all to the same scale. Except for the Sun, all components will be three-dimensional and built to withstand the northern Maine climate. Construction is generally of steel with fiberglass globes positioned on steel posts at least ten feet above ground and 55 feet off the roadway. Road safety concerns require that the Jupiter and Saturn sites include parking lots. Educational information associated with the model will be provided on brochures, since textual information at the sites would require excessive stops and parking problems. Learning exercises will also be provided by travelling trunks prepared by Maine teachers to support the State of Maine Learning Results. This is a community project with the various components being built by ten area schools and with active assistance from many community members and organizations. It is being built with with very little money, with most materials and labor donated.

  4. Spontaneous abortions after the Three Mile Island nuclear accident: a life table analysis.

    PubMed Central

    Goldhaber, M K; Staub, S L; Tokuhata, G K

    1983-01-01

    A study was conducted to determine whether the incidence of spontaneous abortion was greater than expected near the Three Mile Island (TMI) nuclear power plant during the months following the March 28, 1979 accident. All persons living within five miles of TMI were registered shortly after the accident, and information on pregnancy at the time of the accident was collected. After one year, all pregnancy cases were followed up and outcomes ascertained. Using the life table method, it was found that, given pregnancies after four completed weeks of gestation counting from the first day of the last menstrual period, the estimated incidence of spontaneous abortion (miscarriage before completion of 16 weeks of gestation) was 15.1 per cent for women pregnant at the time of the TMI accident. Combining spontaneous abortions and stillbirths (delivery of a dead fetus after 16 weeks of gestation), the estimated incidence was 16.1 per cent for pregnancies after four completed weeks of gestation. Both incidences are comparable to baseline studies of fetal loss. PMID:6859357

  5. Titania - Highest Resolution Voyager Picture

    NASA Technical Reports Server (NTRS)

    1986-01-01

    This is the highest-resolution picture of Titania returned by Voyager 2. The picture is a composite of two images taken Jan. 24, 1986, through the clear filter of Voyager's narrow-angle camera. At the time, the spacecraft was 369,000 kilometers (229,000 miles) from the Uranian moon; the resolution was 13 km (8 mi). Titania is the largest satellite of Uranus, with a diameter of a little more than 1,600 km (1,000 mi). Abundant impact craters of many sizes pockmark the ancient surface. The most prominent features are fault valleys that stretch across Titania. They are up to 1,500 km (nearly 1,000 mi) long and as much as 75 km (45 mi) wide. In valleys seen at right-center, the sunward-facing walls are very bright. While this is due partly to the lighting angle, the brightness also indicates the presence of a lighter material, possibly young frost deposits. An impact crater more than 200 km (125 mi) in diameter distinguishes the very bottom of the disk; the crater is cut by a younger fault valley more than 100 km (60 mi) wide. An even larger impact crater, perhaps 300 km (180 mi) across, is visible at top. The Voyager project is managed for NASA by the Jet Propulsion Laboratory.

  6. Enantioselective Diels-Alder approach to C-3-oxygenated angucyclinones from (SS)-2-(p-tolysulfinyl)-1,4-naphthoquinone.

    PubMed

    Carreño, M C; Urbano, A; Di Vitta, C

    2000-03-03

    Chiral racemic vinylcyclohexenes 2, bearing oxygenated substituents and/or a methyl group at the C-5 position of the cyclohexene ring, were submitted to Diels-Alder reactions with enantiomerically pure (SS)-(2-p-tolylsulfinyl)-1,4-naphthoquinone [(+)-1]. The domino cycloaddition/pyrolytic sulfoxide elimination process led to the formation of enantiomerically enriched angularly tetracyclic quinones anti-6 and syn-7, which were obtained from the kinetic resolution of the racemic diene. In all cases, (SS)-(2-p-tolylsulfinyl)-1,4-naphthoquinone reacted from the less hindered face of the more reactive s-cis conformation, to form products in good enantiomeric excesses. Steric effects and torsional interactions in the corresponding approaches account for the observed pi-facial diastereoselectivities at both partners. The usefulness of this methodology is illustrated with the four-step totally asymmetric synthesis of the C-3-oxygenated angucyclinone derivative (-)-8-deoxytetrangomycin 10 in 26% overall yield and with 50% enantiomeric purity.

  7. Supplement Analysis for the Transmission System Vegetation Management Program FEIS (DOE/EIS-0285/SA-115, Shelton- Fairmount # 1-4)

    SciTech Connect

    Tippetts, Greg P.

    2002-12-20

    Vegetation Management along the Shelton Fairmount # 1-4 230kV & 115kV transmission lines corridor from structure 34/3 through structure 60/2. BPA proposes to remove unwanted vegetation along the right-of- way, access roads and around tower structures along the subject transmission line corridors. Approximately 26 miles of right-of-way will be treated using selective and non-selective methods that include hand cutting, mowing and herbicide treatments. Approximately 1.5 miles of access roads will be cleared using selective and non-selective methods that include hand cutting, mowing and herbicide treatments. Tower sites will be treated 35 feet from center of poles and or tower legs using selective and non-selective methods that include hand cutting, mowing and herbicide treatments. Vegetation management is required for unimpeded operation and maintenance of the subject transmission line. See Section 1of the attached checklist for a complete description of the proposal.

  8. Hours and Miles: Patient and Health System Implications of Transfer for Psychiatric Bed Capacity

    PubMed Central

    O’Neil, Amy M.; Sadosty, Annie T.; Pasupathy, Kalyan S.; Russi, Christopher; Lohse, Christine M.; Campbell, Ronna L.

    2016-01-01

    Introduction An increasing number of behavioral health (BH) patients are presenting to the emergency department (ED) while BH resources continue to decline. This situation-may lead to more external transfers to find care. Methods This is a retrospective cohort study of consecutive patients presenting to a tertiary care academic ED from February 1, 2013, through January 31, 2014. Patients were identified through electronic health record documentation of psychiatric consultation during ED evaluation. We reviewed electronic health records for demographic characteristics, diagnoses, payer source, ED length of stay, ED disposition, arrival method, and distance traveled to an external facility for inpatient admission. Univariable and multivariable associations with transfer to an external facility in comparison with patients admitted internally were evaluated with logistic regression models and summarized with odds ratios (OR). Results We identified 2,585 BH visits, of which 1,083 (41.9%) resulted in discharge. A total of 1,502 patient visits required inpatient psychiatric admission, and of these cases, 177 patients (11.8%; 95% CI = [10.2–13.5]) required transfer to an external facility. The median ED length of stay for transferred patients was 13.9 hours (interquartile range [IQR], 9.3–20.2 hours; range, 3.0–243.0 hours). The median distance for transport was 83 miles (IQR, 42–111 miles; range, 42–237 miles). In multivariable analysis, patients with suicidal or homicidal ideation had increased risk of transfer (odds ratio [OR] [95% CI], 1.93 [1.22–3.06]; P=0.005). Children younger than 18 years (OR [95% CI], 2.34 [1.60–3.40]; P<0.001) and adults older than 65 years (OR [95% CI], 3.46 [1.93–6.19]; P<0.001) were more likely to require transfer and travel farther to access care. Conclusion Patients requiring external transfer for inpatient psychiatric care were found to have prolonged ED lengths of stay. Patients with suicidal and homicidal ideation as well

  9. Wind-tunnel tests of a 1/4 scale model of the Bell XS-1 transonic airplane. 1: Longitudinal stability and control characteristics

    NASA Technical Reports Server (NTRS)

    Donlan, C. J.; Kemp, W. B., Jr.; Polhamus, E. C.

    1976-01-01

    A 1/4 scale model of the Bell XS-1 transonic aircraft was tested in the Langley 300 mile-per-hour 7 by 10 foot tunnel to determine its low speed longitudinal stability and control characteristics. Pertinent longitudinal flying qualities expected of the XS-1 research airplane were estimated from the results of these tests including the effects of compressibility likely to be encountered at speeds below the force break. It appears that the static longitudinal stability and elevator control power will be adequate, but that the elevator control force gradient in steady flight will be undesirably low for all configurations. It is suggested that a centering spring be incorporated in the elevator control system of the airplane in order to increase the control force gradient in steady flight and in maneuvers.

  10. Structural analysis of N,N-diacyl-1,4-dihydropyrazine by variable-temperature NMR and DFT calculation

    NASA Astrophysics Data System (ADS)

    Song, Xiu-qing; Tan, Hong-bo; Yan, Hong; Chang, Yu

    2017-04-01

    N,N-diacyl-1,4-dihydropyrazine derivatives (1) were prepared via an efficient microwave-assisted synthesis. 1 was isolated and unambiguously confirmed by NMR spectra and high-resolution mass spectrometry. The NMR spectra of 1 showed complicated rather than conventional spectroscopy. Variable-temperature experiments and DFT calculation (PES) were used to investigate this phenomenon. DFT calculations confirmed that the structures of the two rotamers of 1 correspond to those determined by NMR in solution, and gave the syn-anti interconversion barriers of rotamers. The results showed that two isomers exist in solution (deuterated solvent) at room temperature, resulting in complicated NMR spectra.

  11. Redesign of the CKM RICH velocity spectrometers for use in a 1/4 GHz unseparated beam

    SciTech Connect

    Cooper, Peter S.; Engelfried, Jurgen; /San Luis Potosi U.

    2004-01-01

    I report here a redesign of the CKM RICH velocity spectrometers for use in a 1/4 GHz unseparated beam adapted to the KTeV beam line and detector hall at Fermilab (P940). The redesigns reported here comprise modest modification to the original designs for CKM(E921) to accommodate the change in beam flux, momentum, and momentum bite of the primary beam. The ultimate performance of the velocity spectrometer systems, as quantified by the missing mass squared resolution for K{sup +} {yields} {pi}{sup +} x{sup 0}, remains largely unchanged from the original design.

  12. Molecular cloning of pigeon UDP-galactose:beta-D-galactoside alpha1,4-galactosyltransferase and UDP-galactose:beta-D-galactoside beta1,4-galactosyltransferase, two novel enzymes catalyzing the formation of Gal alpha1-4Gal beta1-4Gal beta1-4GlcNAc sequence.

    PubMed

    Suzuki, Noriko; Yamamoto, Kazuo

    2010-02-19

    We previously found that pigeon IgG possesses unique N-glycan structures that contain the Gal alpha1-4Gal beta1-4Gal beta1-4GlcNAc sequence at their nonreducing termini. This sequence is most likely produced by putative alpha1,4- and beta1,4-galactosyltransferases (GalTs), which are responsible for the biosynthesis of the Gal alpha1-4Gal and Gal beta1-4Gal sequences on the N-glycans, respectively. Because no such glycan structures have been found in mammalian glycoproteins, the biosynthetic enzymes that produce these glycans are likely to have distinct substrate specificities from the known mammalian GalTs. To study these enzymes, we cloned the pigeon liver cDNAs encoding alpha4GalT and beta4GalT by expression cloning and characterized these enzymes using the recombinant proteins. The deduced amino acid sequence of pigeon alpha4GalT has 58.2% identity to human alpha4GalT and 68.0 and 66.6% identity to putative alpha4GalTs from chicken and zebra finch, respectively. Unlike human and putative chicken alpha4GalTs, which possess globotriosylceramide synthase activity, pigeon alpha4GalT preferred to catalyze formation of the Gal alpha1-4Gal sequence on glycoproteins. In contrast, the sequence of pigeon beta4GalT revealed a type II transmembrane protein consisting of 438 amino acid residues, with no significant homology to the glycosyltransferases so far identified from mammals and chicken. However, hypothetical proteins from zebra finch (78.8% identity), frogs (58.9-60.4%), zebrafish (37.1-43.0%), and spotted green pufferfish (43.3%) were similar to pigeon beta4GalT, suggesting that the pigeon beta4GalT gene was inherited from the common ancestors of these vertebrates. The sequence analysis revealed that pigeon beta4GalT and its homologs form a new family of glycosyltransferases.

  13. Assessing resolution in super-resolution imaging.

    PubMed

    Demmerle, Justin; Wegel, Eva; Schermelleh, Lothar; Dobbie, Ian M

    2015-10-15

    Resolution is a central concept in all imaging fields, and particularly in optical microscopy, but it can be easily misinterpreted. The mathematical definition of optical resolution was codified by Abbe, and practically defined by the Rayleigh Criterion in the late 19th century. The limit of conventional resolution was also achieved in this period, and it was thought that fundamental constraints of physics prevented further increases in resolution. With the recent development of a range of super-resolution techniques, it is necessary to revisit the concept of optical resolution. Fundamental differences in super-resolution modalities mean that resolution is not a directly transferrable metric between techniques. This article considers the issues in resolution raised by these new technologies, and presents approaches for comparing resolution between different super-resolution methods.

  14. NRC plan for cleanup operations at Three Mile Island Unit 2

    SciTech Connect

    Lo, R.; Snyder, B.

    1982-02-01

    This NRC Plan, which defines NRC's functional role in cleanup operations at Three Mile Island Unit 2 and outlines NRC's regulatory responsibilities in fulfilling this role, is the first revision to the initial plan issued in July 1980 (NUREG-0698). Since 1980, a number of policy developments have occurred which will have an impact on the course of cleanup operations. This revision reflects these developments in the area of NRC's review and approval process with regard to cleanup operations as well as NRC's interface with the Department of Energy's involvement in the cleanup and waste disposal. This revision is also intended to update the cleanup schedule by presenting the cleanup progress that has taken place and NRC's role in ongoing and future cleanup activities.

  15. The legacy of Three Mile Island: Implications for today`s DOE challenges

    SciTech Connect

    Coe, R.P.; Williams, M.S.; Conaway, W.T.

    1996-05-01

    In the 16 years following the accident at Three Mile Island, several lessons have been learned, changes have been made, and the US commercial nuclear industry is safer and more reliable. Two major sources of information emerged from this event. First were the important safety issues requiring immediate answers and modifications to existing plants. Second are the lessons involved with the recovery, cleanup, and defueling of TMI-2 and its unprecedented transition into long-term monitored storage. This later had no `immediate` application, but the tasks and methods used in the TMI-2 recovery have strong parallels in the present-day DOE cleanup program. This article discusses the cleanup lessons of TMI-2 in the context of how it would benefit DOE cleanup.

  16. Health-related economic costs of the Three-Mile Island accident.

    PubMed

    Hu, T W; Slaysman, K S

    1984-01-01

    On March 1979, a nuclear power station at Three-Mile Island (TMI) near Harrisburg, Pennsylvania, had a major breakdown. During the two-week period of the accident, about 150,000 residents were evacuated for reasons associated with safety and health. Many residents during and after the accident, regardless of whether they left or stayed, made mental and physical adjustments due to this accident. This paper is to estimate the economic costs incurred by individuals or communities as a result of a change in physical or mental health status and/or a change in health care services due to the TMI accident. The findings indicate that stress symptoms caused by the accident did affect the health-related behaviors of area residents. Of the costs examined, the economic costs of work days lost and physician visits are the largest cost items. There were some increases in consumption of alcohol, cigarettes, and tranquilizers immediately following the accident.

  17. Analysis of the TMI-2 source range monitor during the TMI (Three Mile Island) accident

    SciTech Connect

    Wu, Horng-Yu; Baratta, A.J.; Hsiao, Ming-Yuan; Bandini, B.R.

    1987-06-01

    The source range monitor (SRM) data recorded during the first 4 hours of the Three Mile Island Unit No. 2 (TMI-2) accident following reactor shutdown were analyzed. An effort to simulate the actual SRM response was made by performing a series of neutron transport calculations. Primary emphasis was placed on simulating the changes in SRM response to various system events during the accident, so as to obtain useful information about core conditions at the various stages. Based on the known end-state reactor conditions, the major system events, and the acutal SRM readings, self-consistent estimates were made of core liquid level, void fraction in the coolant, and locations of core materials. This analysis expands the possible interpretation of the SRM data relative to core damage progression. The results appear to be consistent with other studies of the TMI-2 Accident Evaluation Program, and provide information useful for the developemnt and determination of the TMI-2 accident scenario.

  18. The United States Naval Nuclear Propulsion Program - Over 151 Million Miles Safely Steamed on Nuclear Power

    SciTech Connect

    None, None

    2015-03-01

    NNSA’s third mission pillar is supporting the U.S. Navy’s ability to protect and defend American interests across the globe. The Naval Reactors Program remains at the forefront of technological developments in naval nuclear propulsion and ensures a commanding edge in warfighting capabilities by advancing new technologies and improvements in naval reactor performance and reliability. In 2015, the Naval Nuclear Propulsion Program pioneered advances in nuclear reactor and warship design – such as increasing reactor lifetimes, improving submarine operational effectiveness, and reducing propulsion plant crewing. The Naval Reactors Program continued its record of operational excellence by providing the technical expertise required to resolve emergent issues in the Nation’s nuclear-powered fleet, enabling the Fleet to safely steam more than two million miles. Naval Reactors safely maintains, operates, and oversees the reactors on the Navy’s 82 nuclear-powered warships, constituting more than 45 percent of the Navy’s major combatants.

  19. Evaluation of nuclear facility decommissioning projects. Summary report: Three Mile Island Unit 2 polar crane recovery

    SciTech Connect

    Doerge, D.H.; Miller, R.L.

    1984-08-01

    This document summarizes information concerning restoration of the Three Mile Island-Unit 2 Polar Crane to a fully operational condition following the loss of coolant accident experienced on March 28, 1979. The data collected from activity reports, reactor containment entry records, and other sources were placed in a computerized information retrieval/manipulation system which permits extraction/manipulation of specific data which could be utilized in planning for recovery activities should a similar accident occur in a nuclear generating plant. The information is presented in both computer output form and a manually assembled summarization. This report contains only the manpower requirements and radiation exposures actually incurred during recovery operations within the reactor containment and does not include support activities or costs.

  20. Life stage differences in resident coping with restart of the Three Mile Island nuclear generating facility

    SciTech Connect

    Prince-Embury, S.; Rooney, J.F.

    1990-12-01

    A study of residents who remained in the vicinity of Three Mile Island (TMI) immediately following the restart of the nuclear generating plant revealed that older residents employed a more emotion-focused coping style in the face of this event than did younger residents. Coping style was, however, unrelated to the level of psychological symptoms for these older residents, whereas demographic variables were related. Among younger residents, on the other hand, coping style was related to the level of psychological symptoms, whereas demographic variables were not. Among younger residents, emotion-focused coping was associated with more symptoms and problem-focused coping was associated with fewer symptoms, contradicting previous findings among TMI area residents.

  1. CURRENT APPLICATIONS OF THREE MILE ISLAND-2 CORE AND DEBRIS HANDLING AT THE IDAHO NATIONAL LABORATORY

    SciTech Connect

    Carmack, William Jonathan; Braase, Lori Ann

    2015-09-01

    Fuel recovery from severe accidents requires careful planning and execution. The Idaho National Laboratory played a key role in the Three Mile Island (TMI) fuel and core recovery. This involved technology development to locate and handle the damaged fuel; characterization of fuel and debris; analysis of fuel interaction with structural components and materials; development of fuel drying technology for long-term storage. However, one of the critical activities from the TMI project was the extensive effort document all the activities and archive the reports and photos. A historical review of the TMI project at the INL leads to the identification of current applications and considerations for facility designs, fuel handling, robotic applications, material characterization, etc.

  2. Accuracy and generalizability in summaries of affect regulation strategies: comment on Webb, Miles, and Sheeran (2012).

    PubMed

    Augustine, Adam A; Hemenover, Scott H

    2013-05-01

    In their examination of the effectiveness of affect regulation strategies, Webb, Miles, and Sheeran (2012) offered the results of a broad meta-analysis of studies on regulatory interventions. Their analysis provides an alternative to our earlier, more focused meta-analysis of the affect regulation literature (Augustine & Hemenover, 2009). Unfortunately, there are a number of errors and omissions in this new meta-analysis that could lead to misconceptions regarding both our previous work and the state of the affect regulation literature. In this comment, we examine the impact of methodological issues, inconsistent inclusion criteria, variance in manipulations, and what we perceive to be a subjective and inconsistent selection of effect sizes on the accuracy and generalizability of Webb and colleagues' estimates of affect regulation strategy effectiveness.

  3. Galileo view of Moon orbiting the Earth taken from 3.9 million miles

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Eight days after its encounter with the Earth, the Galileo spacecraft was able to look back and capture this remarkable view of the Moon in orbit about the Earth, taken from a distance of about 6.2 million kilometers (3.9 million miles). The picture was constructed from images taken through the violet, red, and 1.0-micron infrared filters. The Moon is in the foreground, moving from left to right. The brightly-colored Earth contrasts strongly with the Moon, which reflects only about one-third as much sunlight as the Earth. Contrast and color have been computer-enhanced for both objects to improve visibility. Antarctica is visible through clouds (bottom). The Moon's far side is seen; the shadowy indentation in the dawn terminator is the south-Pole/Aitken Basin, one of the largest and oldest lunar impact features. Alternate Jet Propulsion Laboratory (JPL) number is P-41508.

  4. Answers to frequently asked questions about cleanup activities at Three Mile Island, Unit 2

    SciTech Connect

    Not Available

    1984-03-01

    This question-and-answer report provides answers in nontechnical language to frequently asked questions about the status of cleanup activities at Three Mile Island, Unit 2. The answers update information first prepared in 1981, shortly after the cleanup got under way. Since then, a variety of important developments in the cleanup has occurred. The information in the report should be read in conjunction with NUREG 1060, a discussion of increased occupational exposure estimates for the cleanup. The questions and answers in this report cover purpose and community involvement, decontamination of water and reactor, fuel removal, radwaste transport, environmental impact, social and economic effects, worker exposures and safety, radiation monitoring, potential for accidents, and schedule and funding.

  5. Analysis of Three Mile Island Unit 2 reactor cooling system transients. Volume 5

    SciTech Connect

    Henrie, J.O.; Postma, A.K.

    1983-08-01

    The reactimeter data recorded on 3/28/79 at Three Mile Island (TMI-2) indicates a number of abrupt transients starting at 13:52. These transients appeared to be the results of very rapid energy releases in the reactor cooling system. A study was initiated by the US Department of Energy to determine the causes and consequences of these transients. The study shows that the transients were not caused by energy releases in the reactor cooling system. They were probably caused by malfunctions in the reactimeter power supply or by reactimeter ground loop faults. Information obtained and observations derived from the study of real energy release transients which occurred during the first day of the TMI-2 loss of coolant accident are presented.

  6. Methods and equations for estimating peak streamflow per square mile in Virginia’s urban basins

    USGS Publications Warehouse

    Austin, Samuel H.

    2014-01-01

    Models are presented that describe Virginia urban area annual peak streamflow per square mile based on basin percent urban area and basin drainage area. Equations are provided to estimate Virginia urban peak flow per square mile of basin drainage area in each of the following annual exceedance probability categories: 0.995, 0.99, 0.95, 0.9, 0.8, 0.67, 0.5, 0.43, 0.2, 0.1, 0.04, 0.02, 0.01, 0.005, and 0.002 (recurrence intervals of 1.005, 1.01, 1.05, 1.11, 1.25, 1.49, 2.0, 2.3, 5, 10, 25, 50, 100, 200, and 500 years, respectively). Equations apply to Virginia drainage basins ranging in size from no less than 1.2 mi2 to no more than 2,400 mi2 containing at least 10 percent urban area, and not more than 96 percent urban area. A total of 115 Virginia drainage basins were analyzed. Actual-by-predicted plots and leverage plots for response variables and explanatory variables in each peak-flow annual exceedance probability category indicate robust model fits and significant explanatory power. Equations for 8 of 15 urban peak-flow response surface models yield R-square values greater than 0.8. Relations identified in statistical models, describing significant increases in urban peak stream discharges as basin urban area increases, affirm empirical relations reported in past studies of change in stream discharge, lag times, and physical streamflow processes, most notably those detailed for urban areas in northern Virginia.

  7. Quaternary geology and sedimentary processes in the vicinity of Six Mile Reef, eastern Long Island Sound

    USGS Publications Warehouse

    Poppe, L.J.; Williams, S.J.; Moser, M.S.; Forfinski, N.A.; Stewart, H.F.; Doran, E.F.

    2008-01-01

    Six Mile Reef, a sandy, 22-m-high shoal trending east-west and located about 7.8 km off the Connecticut coast, has a core of postglacial marine deltaic deposits mantled by tidally reworked modern sediments. Sedimentary environments off the eastern end of the shoal are characterized by processes associated with long-term erosion or nondeposition, a mobile-sediment-limited seafloor armored by gravelly sand, and scattered elongate fields of barchanoid sand waves. The barchanoid waves reach amplitudes of 20 m, are concave westward, and occur in individual and coalesced forms that become progressively more complex westward. The seafloor on and adjacent to the shoal is characterized by processes associated with coarse bedload transport and covered primarily with asymmetrical transverse sand waves. The transverse waves exceed 8 m in amplitude, have slip faces predominantly oriented to the west and southwest, and have straight, slightly sinuous, and curved crests. Megaripples, which mimic the asymmetry of the sand waves, are commonly present on stoss slopes and in troughs; current ripples are ubiquitous. The amplitude and abundance of large bedforms decrease markedly westward of Six Mile Reef. The seabed there is covered with small, degraded ripples, reflecting lower-energy environments and processes associated with sorting and reworking of seafloor sediments. Megaripples and current ripples on the sand waves suggest that transport is active and that the bedforms are propagating under the present hydraulic regime. Net bedload sediment transport is primarily to the west, as evidenced by textural trends of surficial sediments, orientation of the barchanoid waves, and asymmetry of the transverse waves and of the scour marks around bedrock outcrops, boulders, and shipwrecks. One exception occurs at the western tip of the shoal, where sand-wave morphology indicates long-term eastward transport, suggesting that countercurrents in this area shape the shoal and are important to

  8. Extension of Miles Equation for Ring Baffle Damping Predictions to Small Slosh Amplitudes and Large Baffle Widths

    NASA Technical Reports Server (NTRS)

    West, Jeff; Yang, H. Q.; Brodnick, Jacob; Sansone, Marco; Westra, Douglas

    2016-01-01

    The Miles equation has long been used to predict slosh damping in liquid propellant tanks due to ring baffles. The original work by Miles identifies defined limits to its range of application. Recent evaluations of the Space Launch System identified that the Core Stage baffle designs resulted in violating the limits of the application of the Miles equation. This paper describes the work conducted by NASA/MSFC to develop methods to predict slosh damping from ring baffles for conditions for which Miles equation is not applicable. For asymptotically small slosh amplitudes or conversely large baffle widths, an asymptotic expression for slosh damping was developed and calibrated using historical experimental sub-scale slosh damping data. For the parameter space that lies between region of applicability of the asymptotic expression and the Miles equation, Computational Fluid Dynamics simulations of slosh damping were used to develop an expression for slosh damping. The combined multi-regime slosh prediction methodology is shown to be smooth at regime boundaries and consistent with both sub-scale experimental slosh damping data and the results of validated Computational Fluid Dynamics predictions of slosh damping due to ring baffles.

  9. Photostabilization studies of antihypertensive 1,4-dihydropyridines using polymeric containers.

    PubMed

    De Luca, Michele; Ioele, Giuseppina; Spatari, Claudia; Ragno, Gaetano

    2016-05-30

    1,4-dihydropyridine antihypertensives (DHPs) are almost all dispensed in solid pharmaceutical formulations for their easy lability when exposed to light. This paper reports a study on the photoprotective effect of containers in different glassy or polymeric matrices with regard to four known DHPs when in solutions. The samples were subjected to forced degradation by means of a Xenon lamp, in accordance with the international rules on drug stability evaluation. The simultaneous determination of the drugs and their photoproducts was carried out by applying the multivariate curve resolution (MCR) methodology to the spectral data recorded along the irradiation test. This technique was able to determine the kinetic parameters and resolve the spectra of the photoproducts. The time required to reduce by 10% the concentration of the drug (t0.1) was adopted as a criterion to compare the protective ability of the containers. A significant photoprotection for all drugs tested was obtained by the use of polyethylene terephthalate (PET) containers. The best result was achieved for the felodipine solution in blue PET transparent bottle of 0.6mm thickness, reaching an almost complete stabilization up to six hours under stressing irradiation. In contrast, the glass containers, whether or not coloured, did not provide a satisfactory photoprotection of the drugs, showing in any case t0.1 values under 24min. These results can be a good opportunity to design new photoprotective pharmaceutical packaging for DHPs in liquid dosage form.

  10. Climate applications for NOAA 1/4° Daily Optimum Interpolation Sea Surface Temperature

    NASA Astrophysics Data System (ADS)

    Boyer, T.; Banzon, P. V. F.; Liu, G.; Saha, K.; Wilson, C.; Stachniewicz, J. S.

    2015-12-01

    Few sea surface temperature (SST) datasets from satellites have the long temporal span needed for climate studies. The NOAA Daily Optimum Interpolation Sea Surface Temperature (DOISST) on a 1/4° grid, produced at National Centers for Environmental Information, is based primarily on SSTs from the Advanced Very High Resolution Radiometer (AVHRR), available from 1981 to the present. AVHRR data can contain biases, particularly when aerosols are present. Over the three decade span, the largest departure of AVHRR SSTs from buoy temperatures occurred during the Mt Pinatubo and El Chichon eruptions. Therefore, in DOISST, AVHRR SSTs are bias-adjusted to match in situ SSTs prior to interpolation. This produces a consistent time series of complete SST fields that is suitable for modelling and investigating local climate phenomena like El Nino or the Pacific warm blob in a long term context. Because many biological processes and animal distributions are temperature dependent, there are also many ecological uses of DOISST (e.g., coral bleaching thermal stress, fish and marine mammal distributions), thereby providing insights into resource management in a changing ocean. The advantages and limitations of using DOISST for different applications will be discussed.

  11. Near infrared cavity enhanced absorption spectra of atmospherically relevant ether-1, 4-Dioxane

    NASA Astrophysics Data System (ADS)

    Chandran, Satheesh; Varma, Ravi

    2016-01-01

    1, 4-Dioxane (DX) is a commonly found ether in industrially polluted atmosphere. The near infrared absorption spectra of this compound has been recorded in the region 5900-8230 cm- 1 with a resolution of 0.08 cm- 1 using a novel Fourier transform incoherent broadband cavity-enhanced absorption spectrometer (FT-IBBCEAS). All recorded spectra were found to contain regions that are only weakly perturbed. The possible combinations of fundamental modes and their overtone bands corresponding to selected regions in the measured spectra are tabulated. Two interesting spectral regions were identified as 5900-6400 cm- 1 and 8100-8230 cm- 1. No significant spectral interference due to presence of water vapor was observed suggesting the suitability of these spectral signatures for spectroscopic in situ detection of DX. The technique employed here is much more sensitive than standard Fourier transform spectrometer measurements on account of long effective path length achieved. Hence significant enhancement of weaker absorption lines above the noise level was observed as demonstrated by comparison with an available measurement from database.

  12. Functional and structural analyses of a 1,4-β-endoglucanase from Ganoderma lucidum.

    PubMed

    Liu, Guizhi; Li, Qian; Shang, Na; Huang, Jian-Wen; Ko, Tzu-Ping; Liu, Weidong; Zheng, Yingying; Han, Xu; Chen, Yun; Chen, Chun-Chi; Jin, Jian; Guo, Rey-Ting

    2016-05-01

    Ganoderma lucidum is a saprotrophic white-rot fungus which contains a rich set of cellulolytic enzymes. Here, we screened an array of potential 1,4-β-endoglucanases from G. lucidum based on the gene annotation library and found that one candidate gene, GlCel5A, exhibits CMC-hydrolyzing activity. The recombinant GlCel5A protein expressed in Pichia pastoris is able to hydrolyze CMC and β-glucan but not xylan and mannan. The enzyme exhibits optimal activity at 60°C and pH 3-4, and retained 50% activity at 80 and 90°C for at least 15 and 10min. The crystal structure of GlCel5A and its complex with cellobiose, solved at 2.7 and 2.86Å resolution, shows a classical (β/α)8 TIM-barrel fold as seen in other members of glycoside hydrolase family 5. The complex structure contains a cellobiose molecule in the +1 and +2 subsites, and reveals the interactions with the positive sites of the enzyme. Collectively, the present work provides the first comprehensive characterization of an endoglucanase from G. lucidum that possesses properties for industrial applications, and strongly encourages further studying in the cellulolytic enzyme system of G. lucidum.

  13. Tier 2 Intermediate Useful Life (50,000 Miles) and 4000 Mile Supplemental Federal Test Procedure (SFTP) Exhaust Emission Results for a NOx Adsorber and Diesel Particle Filter Equipped Light-Duty Diesel Vehicle

    SciTech Connect

    Tatur, M.; Tyrer, H.; Tomazic, D.; Thornton, M.; McDonald, J.

    2005-01-01

    Due to its high efficiency and superior durability the diesel engine is again becoming a prime candidate for future light-duty vehicle applications within the United States. While in Europe the overall diesel share exceeds 40%, the current diesel share in the U.S. is 1%. Despite the current situation and the very stringent Tier 2 emission standards, efforts are being made to introduce the diesel engine back into the U.S. market. In order to succeed, these vehicles have to comply with emissions standards over a 120,000 miles distance while maintaining their excellent fuel economy. The availability of technologies such as high-pressure, common-rail fuel systems, low-sulfur diesel fuel, NO{sub x} adsorber catalysts (NAC), and diesel particle filters (DPFs) allow the development of powertrain systems that have the potential to comply with the light-duty Tier 2 emission requirements. In support of this, the U.S. Department of Energy (DOE) has engaged in several test projects under the Advanced Petroleum Based Fuels - Diesel Emission Controls (APBF-DEC) activity. The primary technology being addressed by these projects are the sulfur tolerance and durability of the NAC/DPF system. The project investigated the performance of the emission control system and system desulphurization effects on regulated and unregulated emissions. Emissions measurements were conducted over the Federal Test Procedure (FTP), Supplemental Federal Test Procedure (SFTP), and the Highway Fuel Economy Test (HFET). Testing was conducted after the accumulation of 150 hours of engine operation calculated to be the equivalent of approximately 8,200 miles. For these evaluations three out of six of the FTP test cycles were within the 50,000-mile Tier 2 bin 5 emission standards (0.05 g/mi NO{sub x} and 0.01 g/mi PM). Emissions over the SC03 portion of the SFTP were within the 4,000-mile SFTP standards. The emission of NO{sub x}+NMHC exceeded the 4,000-mile standard over the US06 portion of the SFTP

  14. 49 CFR 174.115 - Loading Division 1.4 (explosive) materials.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... RAIL Class I (Explosive) Materials § 174.115 Loading Division 1.4 (explosive) materials. (a) Division 1... Pamphlet No. 6. (b) Division 1.4 (explosive) materials may not be transported in a truck body, trailer,...

  15. 49 CFR 173.64 - Exceptions for Division 1.3 and 1.4 fireworks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Exceptions for Division 1.3 and 1.4 fireworks. 173... § 173.64 Exceptions for Division 1.3 and 1.4 fireworks. (a) Notwithstanding the requirements of § 173.56(b), Division 1.3 and 1.4 fireworks (see § 173.65 for Division 1.4G consumer fireworks) may...

  16. 49 CFR 173.64 - Exceptions for Division 1.3 and 1.4 fireworks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Exceptions for Division 1.3 and 1.4 fireworks. 173... § 173.64 Exceptions for Division 1.3 and 1.4 fireworks. (a) Notwithstanding the requirements of § 173.56(b), Division 1.3 and 1.4 fireworks (see § 173.65 for Division 1.4G consumer fireworks) may...

  17. Flood-inundation maps for an 8.9-mile reach of the South Fork Little River at Hopkinsville, Kentucky

    USGS Publications Warehouse

    Lant, Jeremiah G.

    2013-01-01

    Digital flood-inundation maps for an 8.9-mile reach of South Fork Little River at Hopkinsville, Kentucky, were created by the U.S. Geological Survey (USGS) in cooperation with the City of Hopkinsville Community Development Services. The inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation/ depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the USGS streamgage at South Fork Little River at Highway 68 By-Pass at Hopkinsville, Kentucky (station no. 03437495). Current conditions for the USGS streamgage may be obtained online at the USGS National Water Information System site (http://waterdata.usgs.gov/nwis/inventory?agency_code=USGS&site_no=03437495). In addition, the information has been provided to the National Weather Service (NWS) for incorporation into their Advanced Hydrologic Prediction Service flood warning system (http://water.weather.gov/ahps/). The NWS forecasts flood hydrographs at many places that are often co-located at USGS streamgages. The forecasted peak-stage information, also available on the Internet, may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. In this study, flood profiles were computed for the South Fork Little River reach by using HEC-RAS, a one-dimensional step-backwater model developed by the U.S. Army Corps of Engineers. The hydraulic model was calibrated by using the most current (2012) stage-discharge relation at the South Fork Little River at Highway 68 By-Pass at Hopkinsville, Kentucky, streamgage and measurements collected during recent flood events. The calibrated model was then used to calculate 13 water-surface profiles for a sequence of flood stages, most at 1-foot intervals, referenced to the streamgage datum and ranging from a stage near bank full to the estimated elevation of the 1.0-percent annual exceedance

  18. Flood-inundation maps for a 6.5-mile reach of the Kentucky River at Frankfort, Kentucky

    USGS Publications Warehouse

    Lant, Jeremiah G.

    2013-01-01

    Digital flood-inundation maps for a 6.5-mile reach of Kentucky River at Frankfort, Kentucky, were created by the U.S. Geological Survey (USGS) in cooperation with the City of Frankfort Office of Emergency Management. The inundation maps, which can be accessed through the USGS Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation/, depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the USGS streamgage Kentucky River at Lock 4 at Frankfort, Kentucky (station no. 03287500). Current conditions for the USGS streamgage may be obtained online at the USGS National Water Information System site (http://waterdata.usgs.gov/nwis/inventory?agency_code=USGS&site_no=03287500). In addition, the information has been provided to the National Weather Service (NWS) for incorporation into their Advanced Hydrologic Prediction Service (AHPS) flood warning system (http:/water.weather.gov/ahps/). The NWS forecasts flood hydrographs at many places that are often colocated at USGS streamgages. The forecasted peak-stage information, also available on the Internet, may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. In this study, flood profiles were computed for the Kentucky River reach by using HEC–RAS, a one-dimensional step-backwater model developed by the U.S. Army Corps of Engineers. The hydraulic model was calibrated by using the most current (2013) stage-discharge relation for the Kentucky River at Lock 4 at Frankfort, Kentucky, in combination with streamgage and high-water-mark measurements collected for a flood event in May 2010. The calibrated model was then used to calculate 26 water-surface profiles for a sequence of flood stages, at 1-foot intervals, referenced to the streamgage datum and ranging from a stage near bankfull to the elevation that breached the levees protecting the City of Frankfort. To delineate the flooded area at

  19. 43 CFR 8365.1-4 - Public health, safety and comfort.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Public health, safety and comfort. 8365.1-4 Section 8365.1-4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF... § 8365.1-4 Public health, safety and comfort. (a) No person shall cause a public disturbance or create...

  20. 43 CFR 8365.1-4 - Public health, safety and comfort.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Public health, safety and comfort. 8365.1-4 Section 8365.1-4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF... § 8365.1-4 Public health, safety and comfort. (a) No person shall cause a public disturbance or create...

  1. 43 CFR 8365.1-4 - Public health, safety and comfort.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Public health, safety and comfort. 8365.1-4 Section 8365.1-4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF... § 8365.1-4 Public health, safety and comfort. (a) No person shall cause a public disturbance or create...

  2. 43 CFR 8365.1-4 - Public health, safety and comfort.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Public health, safety and comfort. 8365.1-4 Section 8365.1-4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF... § 8365.1-4 Public health, safety and comfort. (a) No person shall cause a public disturbance or create...

  3. 40 CFR 721.10096 - Benzene, 1,4-bis (methoxymethyl)-.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Benzene, 1,4-bis (methoxymethyl)-. 721... Substances § 721.10096 Benzene, 1,4-bis (methoxymethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 1,4-bis (methoxymethyl)- (PMN...

  4. 40 CFR 721.1193 - Benzene, 2-bromo-1,4-dimethoxy-.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Benzene, 2-bromo-1,4-dimethoxy-. 721... Substances § 721.1193 Benzene, 2-bromo-1,4-dimethoxy-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 2-bromo-1,4-dimethoxy- (PMN...

  5. 40 CFR 721.1193 - Benzene, 2-bromo-1,4-dimethoxy-.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Benzene, 2-bromo-1,4-dimethoxy-. 721... Substances § 721.1193 Benzene, 2-bromo-1,4-dimethoxy-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 2-bromo-1,4-dimethoxy- (PMN...

  6. 40 CFR 721.10096 - Benzene, 1,4-bis (methoxymethyl)-.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Benzene, 1,4-bis (methoxymethyl)-. 721... Substances § 721.10096 Benzene, 1,4-bis (methoxymethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 1,4-bis (methoxymethyl)- (PMN...

  7. 40 CFR 721.1193 - Benzene, 2-bromo-1,4-dimethoxy-.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Benzene, 2-bromo-1,4-dimethoxy-. 721... Substances § 721.1193 Benzene, 2-bromo-1,4-dimethoxy-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 2-bromo-1,4-dimethoxy- (PMN...

  8. 40 CFR 721.10096 - Benzene, 1,4-bis (methoxymethyl)-.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Benzene, 1,4-bis (methoxymethyl)-. 721... Substances § 721.10096 Benzene, 1,4-bis (methoxymethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 1,4-bis (methoxymethyl)- (PMN...

  9. 40 CFR 721.1193 - Benzene, 2-bromo-1,4-dimethoxy-.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Benzene, 2-bromo-1,4-dimethoxy-. 721... Substances § 721.1193 Benzene, 2-bromo-1,4-dimethoxy-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 2-bromo-1,4-dimethoxy- (PMN...

  10. 40 CFR 721.10096 - Benzene, 1,4-bis (methoxymethyl)-.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Benzene, 1,4-bis (methoxymethyl)-. 721... Substances § 721.10096 Benzene, 1,4-bis (methoxymethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 1,4-bis (methoxymethyl)- (PMN...

  11. 40 CFR 721.1193 - Benzene, 2-bromo-1,4-dimethoxy-.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Benzene, 2-bromo-1,4-dimethoxy-. 721... Substances § 721.1193 Benzene, 2-bromo-1,4-dimethoxy-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 2-bromo-1,4-dimethoxy- (PMN...

  12. 40 CFR 721.10096 - Benzene, 1,4-bis (methoxymethyl)-.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Benzene, 1,4-bis (methoxymethyl)-. 721... Substances § 721.10096 Benzene, 1,4-bis (methoxymethyl)-. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as benzene, 1,4-bis (methoxymethyl)- (PMN...

  13. 47 CFR 27.806 - 1.4 GHz service licenses subject to competitive bidding.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false 1.4 GHz service licenses subject to competitive bidding. 27.806 Section 27.806 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1.4 GHz Band § 27.806 1.4 GHz...

  14. 47 CFR 27.806 - 1.4 GHz service licenses subject to competitive bidding.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false 1.4 GHz service licenses subject to competitive bidding. 27.806 Section 27.806 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1.4 GHz Band § 27.806 1.4 GHz...

  15. 47 CFR 27.806 - 1.4 GHz service licenses subject to competitive bidding.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false 1.4 GHz service licenses subject to competitive bidding. 27.806 Section 27.806 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1.4 GHz Band § 27.806 1.4 GHz...

  16. 47 CFR 27.806 - 1.4 GHz service licenses subject to competitive bidding.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false 1.4 GHz service licenses subject to competitive bidding. 27.806 Section 27.806 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1.4 GHz Band § 27.806 1.4 GHz...

  17. 47 CFR 27.806 - 1.4 GHz service licenses subject to competitive bidding.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false 1.4 GHz service licenses subject to competitive bidding. 27.806 Section 27.806 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1.4 GHz Band § 27.806 1.4 GHz...

  18. IRIS Toxicological Review of 1,4-Dioxane (with Inhalation Update) (Final Report)

    EPA Science Inventory

    The final IRIS Toxicological Review of 1,4-dioxane (with inhalation update) provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to 1,4-dioxane. Human health risk concerns for 1,4-dioxane are primarily relat...

  19. 10 CFR 960.3-1-4-3 - Site recommendation for characterization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Site recommendation for characterization. 960.3-1-4-3 Section 960.3-1-4-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-3 Site...

  20. 10 CFR 960.3-1-4 - Evidence for siting decisions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Evidence for siting decisions. 960.3-1-4 Section 960.3-1-4 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4 Evidence for siting decisions. The...

  1. 10 CFR 960.3-1-4 - Evidence for siting decisions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Evidence for siting decisions. 960.3-1-4 Section 960.3-1-4 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4 Evidence for siting decisions. The...

  2. 10 CFR 960.3-1-4-1 - Site identification as potentially acceptable.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Site identification as potentially acceptable. 960.3-1-4-1 Section 960.3-1-4-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-1 Site...

  3. 10 CFR 960.3-1-4-3 - Site recommendation for characterization.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Site recommendation for characterization. 960.3-1-4-3 Section 960.3-1-4-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-3 Site...

  4. 10 CFR 960.3-1-4 - Evidence for siting decisions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Evidence for siting decisions. 960.3-1-4 Section 960.3-1-4 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4 Evidence for siting decisions. The...

  5. 10 CFR 960.3-1-4-3 - Site recommendation for characterization.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Site recommendation for characterization. 960.3-1-4-3 Section 960.3-1-4-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-3 Site...

  6. 10 CFR 960.3-1-4-1 - Site identification as potentially acceptable.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Site identification as potentially acceptable. 960.3-1-4-1 Section 960.3-1-4-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-1 Site...

  7. 10 CFR 960.3-1-4-3 - Site recommendation for characterization.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Site recommendation for characterization. 960.3-1-4-3 Section 960.3-1-4-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-3 Site...

  8. 10 CFR 960.3-1-4 - Evidence for siting decisions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Evidence for siting decisions. 960.3-1-4 Section 960.3-1-4 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4 Evidence for siting decisions. The...

  9. 10 CFR 960.3-1-4 - Evidence for siting decisions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Evidence for siting decisions. 960.3-1-4 Section 960.3-1-4 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4 Evidence for siting decisions. The...

  10. 10 CFR 960.3-1-4-1 - Site identification as potentially acceptable.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Site identification as potentially acceptable. 960.3-1-4-1 Section 960.3-1-4-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-1 Site...

  11. 10 CFR 960.3-1-4-1 - Site identification as potentially acceptable.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Site identification as potentially acceptable. 960.3-1-4-1 Section 960.3-1-4-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-1 Site...

  12. 10 CFR 960.3-1-4-3 - Site recommendation for characterization.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Site recommendation for characterization. 960.3-1-4-3 Section 960.3-1-4-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-3 Site...

  13. 17 CFR 240.11a1-4(T) - Bond transactions on national securities exchanges.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Bond transactions on national securities exchanges. 240.11a1-4(T) Section 240.11a1-4(T) Commodity and Securities Exchanges SECURITIES AND....11a1-4(T) Bond transactions on national securities exchanges. A transaction in a bond, note,...

  14. Hydrology and modeling of flow conditions at Bridge 339 and Mile 38-43, Copper River Highway, Alaska

    USGS Publications Warehouse

    Brabets, Timothy P.

    2012-01-01

    The Copper River basin, the sixth largest watershed in Alaska, drains an area of 24,200 square miles in south-central Alaska. This large, glacier-fed river flows across a wide alluvial fan before it enters the Gulf of Alaska. The Copper River Highway, which traverses the alluvial fan, has been affected by channel planform reconfiguration. Currently (2012), two areas of the Copper River Highway are at risk: at Mile 38-43, the road grade is too low and the highway could be flooded by high flows of the Copper River, and at Mile 36, the main channel of the Copper River has migrated directly toward Bridge 339. Because Bridge 339 was not designed and built to convey the main flow of the Copper River, as much as 50 feet of scour occurred at the piers in 2011. The piers can no longer absorb the lateral or vertical loads, resulting in closure of the bridge and the Copper River Highway. The U.S. Geological Survey Flow and Sediment Transport with Morphologic Evolution of Channels (FaSTMECH) model was used to simulate the flow of the Copper River and produce simulations of depth, water-surface elevation, and velocity. At the Mile 38-43 area, FaSTMECH was used to analyze the effects of raising the road grade 5 feet, and at Mile 36, FaSTMECH was used to analyze the effects of constructing a channel to divert flow away from Bridge 339. Results from FaSTMECH indicate that if raising the road grade 5 feet in the Mile 38-43 area, a flood with an annual exceedance probability of 2 percent (400,000 cubic feet per second) would not overtop the highway. In the Bridge 339 area, results from FaSTMECH indicate that a design channel could divert flows as much as 100,000 cubic feet per second away from Bridge 339.

  15. The transient outward current in mice lacking the potassium channel gene Kv1.4

    PubMed Central

    London, Barry; Wang, Dao W; Hill, Joseph A; Bennett, Paul B

    1998-01-01

    The transient outward current (Ito) plays a prominent role in the repolarization phase of the cardiac action potential. Several K+ channel genes, including Kv1.4, are expressed in the heart, produce rapidly inactivating currents when heterologously expressed, and may be the molecular basis of Ito.We engineered mice homozygous for a targeted disruption of the K+ channel gene Kv1.4 and compared Ito in wild-type (Kv1.4+/+), heterozygous (Kv1.4+/-) and homozygous ‘knockout’ (Kv1.4−/−) mice. Kv1.4 RNA was truncated in Kv1.4−/− mice and protein expression was absent.Adult myocytes isolated from Kv1.4+/+, Kv1.4+/− and Kv1.4−/− mice had large rapidly inactivating outward currents. The peak current densities at 60 mV (normalized by cellular capacitance, in pA pF−1; means ± s.e.m.) were 53.8 ± 5.3, 45.3 ± 2.2 and 44.4 ± 2.8 in cells from Kv1.4+/+, Kv1.4+/− and Kv1.4−/− mice, respectively (P < 0.02 for Kv1.4+/+ vs. Kv1.4−/−). The steady-state values (800 ms after the voltage clamp step) were 30.9 ± 2.9, 26.9 ± 3.8 and 23.5 ± 2.2, respectively (P < 0.02 for Kv1.4+/+ vs. Kv1.4−/−). The inactivating portion of the current was unchanged in the targeted mice.The voltage dependence and time course of inactivation were not changed by targeted disruption of Kv1.4. The mean best-fitting V½ (membrane potential at 50 % inactivation) values for myocytes from Kv1.4 +/+, Kv1.4+/− and Kv1.4−/− mice were -53.5 ± 3.7, -51.1 ± 2.6 and -54.2 ± 2.4 mV, respectively. The slope factors (k) were -10.1 ± 1.4, -8.8 ± 1.4 and -9.5 ± 1.2 mV, respectively. The fast time constants for development of inactivation at -30 mV were 27.8 ± 2.2, 26.2 ± 5.1 and 19.6 ± 2.1 ms in Kv1.4+/+, Kv1.4+/− and Kv1.4−/− myocytes, respectively. At +30 mV, they were 35.5 ± 2.6, 30.0 ± 2.1 and 28.7 ± 1.6 ms, respectively. The time constants for the rapid phase of recovery from inactivation at -80 mV were 32.5 ± 8.2, 23.3 ± 1.8 and 39.0 ± 3.7 ms, respectively

  16. Biaryl synthesis by ring-opening Friedel-Crafts arylation of 1,4-epoxy-1,4-dihydronaphthalenes catalyzed by iron trichloride.

    PubMed

    Sawama, Yoshinari; Asai, Shota; Kawajiri, Takahiro; Monguchi, Yasunari; Sajiki, Hironao

    2015-01-26

    Biaryl and heterobiaryl compounds are important frameworks across a range of fields including pharmaceutical and functional material chemistries. We have accomplished the efficient synthesis of various naphthalene-linked arenes and heteroarenes as biaryls and heterobiaryls by the FeCl3 -catalyzed Friedel-Crafts reactions accompanied by the ring-opening of the 1,4-epoxy moiety of 1,4-epoxy-1,4-dihydronaphthalenes. Especially, it is noteworthy that 1-silylated substrates were regioselectively transformed to the 3-aryl-1-silylnaphthalenes and the double Friedel-Crafts reactions using thiophene derivatives could directly produce the corresponding bis-naphthlated thiophene derivatives.

  17. Improvement of the chromatographic separation of several 1,4-dihydropyridines calcium channel antagonist drugs by experimental design.

    PubMed

    Baranda, Ana B; Etxebarria, Nestor; Jiménez, Rosa M; Alonso, Rosa M

    2005-01-01

    A high-performance liquid chromatographic method with diode array detection has been developed and optimized for the separation of five calcium channel blockers belonging to the 1,4-dihydropyridine subgroup (nifedipine and related drugs). The possibility of the simultaneous drug analysis allows a decrease of time during the assay as well as a saving of reagents and solvents. In this work, the effect of four experimental parameters (organic modifier percentage, pH value, concentration of the buffer in the mobile phase, and column temperature) on the chromatographic resolution are investigated by experimental design in order to optimize the chromatographic separation of five 1,4-dihydropyridines (amlodipine, nitrendipine, felodipine, lacidipine, and lercanidipine). Fractional factorial design, central composite design, and finally the Multisimplex program are used to establish the optimal conditions in terms of resolution and minimum analysis time. Optimal separation of the five compounds under study is achieved in less than 12 min using a Sulpecosil LC-ABZ+Plus C18 column, a composition of mobile phase of acetonitrile-10mM acetic acid acetate buffer pH 5 (72:28, v/v) at a flow rate of 1 mL/min, a column temperature of 30 degrees C +/- 0.1 degrees C, and a detection wavelength of 238 nm.

  18. Very High Resolution Image of Icy Cliffs on Europa

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This image, taken by the camera onboard NASA's Galileo spacecraft, is a very high resolution view of the Conamara Chaos region on Jupiter's moon Europa. It shows an area where icy plates have been broken apart and moved around laterally. The top of this image is dominated by corrugated plateaus ending in icy cliffs over a hundred meters (a few hundred feet) high. Debris piled at the base of the cliffs can be resolved down to blocks the size of a house. A fracture that runs horizontally across and just below the center of the Europa image is about the width of a freeway.

    North is to the top right of the image, and the sun illuminates the surface from the east. The image is centered at approximately 9 degrees north latitude and 274 degrees west longitude. The image covers an area approximately 1.7 kilometers by 4 kilometers (1 mile by 2.5 miles). The resolution is 9 meters (30 feet) per picture element. This image was taken on December 16, 1997 at a range of 900 kilometers (540 miles) by Galileo's solid state imaging system.

    The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).

    This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://www.jpl.nasa.gov/ galileo.

  19. Explaining the Cyclic Voltammetry of a Poly(1,4-phenylene-ethynylene)-alt-poly(1,4-phenylene-vinylene) Copolymer upon Oxidation by using Spectroscopic Techniques.

    PubMed

    Enengl, Christina; Enengl, Sandra; Bouguerra, Nassima; Havlicek, Marek; Neugebauer, Helmut; Egbe, Daniel A M

    2017-01-04

    Poly(1,4-phenylene-ethynylene)-alt-poly(1,4-phenylene-vinylene) (PPE-PPV) copolymers have attracted quite a lot of attention in the last few years for electronic device applications owing to their enhanced fluorescence. In this work, we focus on one particular PPE-PPV copolymer with dissymmetrically substituted 1,4-phenylene-ethynylene and symmetrically substituted 1,4-phenylene-vinylene building units. Six successively performed cyclic voltammograms are presented, measured during the oxidation reactions. As the oxidation onset of the electrochemical reaction shifts to lower potentials in each cycle, this behavior is elucidated by using spectroscopic techniques ranging from UV/Vis/near-IR to mid-IR including spin-resonance techniques. Hence, these findings help to explain some of the copolymer's most advantageous properties in terms of possible oxidation products.

  20. Modeling Weather Impact on Airport Arrival Miles-in-Trail Restrictions

    NASA Technical Reports Server (NTRS)

    Wang, Yao; Grabbe, Shon

    2013-01-01

    When the demand for either a region of airspace or an airport approaches or exceeds the available capacity, miles-in-trail (MIT) restrictions are the most frequently issued traffic management initiatives (TMIs) that are used to mitigate these imbalances. Miles-intrail operations require aircraft in a traffic stream to meet a specific inter-aircraft separation in exchange for maintaining a safe and orderly flow within the stream. This stream of aircraft can be departing an airport, over a common fix, through a sector, on a specific route or arriving at an airport. This study begins by providing a high-level overview of the distribution and causes of arrival MIT restrictions for the top ten airports in the United States. This is followed by an in-depth analysis of the frequency, duration and cause of MIT restrictions impacting the Hartsfield-Jackson Atlanta International Airport (ATL) from 2009 through 2011. Then, machine-learning methods for predicting (1) situations in which MIT restrictions for ATL arrivals are implemented under low demand scenarios, and (2) days in which a large number of MIT restrictions are required to properly manage and control ATL arrivals are presented. More specifically, these predictions were accomplished by using an ensemble of decision trees with Bootstrap aggregation (BDT) and supervised machine learning was used to train the BDT binary classification models. The models were subsequently validated using data cross validation methods. When predicting the occurrence of arrival MIT restrictions under low demand situations, the model was able to achieve over all accuracy rates ranging from 84% to 90%, with false alarm ratios ranging from 10% to 15%. In the second set of studies designed to predict days on which a high number of MIT restrictions were required, overall accuracy rates of 80% were achieved with false alarm ratios of 20%. Overall, the predictions proposed by the model give better MIT usage information than what has been

  1. Cancer incidence among residents of the Three Mile Island accident area: 1982-1995

    SciTech Connect

    Han, Yueh-Ying; Youk, Ada O.; Sasser, Howell; Talbott, Evelyn O.

    2011-11-15

    Background: The Pennsylvania Department of Health established a registry of the Three Mile Island (TMI) nuclear power plant accident in 1979. Over 93% of the population present on the day of the accident within a 5-mile radius was enrolled and interviewed. We used the registry to investigate the potential cancer risk from low-dose radiation exposure among the TMI population. Methods: Cancer incidence data among the TMI cohort were available from 1982 to 1995. Because more than 97% of the population were white and few cancer cases were reported for those younger than 18 years of age, we included whites of age 18 years and older (10,446 men and 11,048 women) for further analyses. Cox regression models were used to estimate the relative risk (RR) per 0.1 m Sv and 95% confident interval (CI) of cancer by radiation-related exposures. The cancers of interest were all malignant neoplasms, cancer of bronchus, trachea, and lung, cancer of lymphatic and hematopoietic tissues, leukemia, and female breast. Results: Among men and women, there was no evidence of an increased risk for all malignant neoplasms among the TMI cohort exposed to higher maximum and likely {gamma} radiation (RR=1.00, 95% CI=0.97, 1.01 and RR=0.99, 95% CI=0.94, 1.03, respectively) after adjusting for age, gender, education, smoking, and background radiation. Elevation in risk was noted for cancer of the bronchus, trachea, and lung in relation to higher background radiation exposure (RR=1.45, 95% CI=1.02-2.05 at 8.0-8.8 {mu}R/h compared to 5.2-7.2 {mu}R/h). An increased risk of leukemia was found among men exposed to higher maximum and likely {gamma} radiation related to TMI exposure during the ten days following the accident (RR=1.15, 95% CI=1.04, 1.29 and RR=1.36, 95% CI=1.08, 1.71, respectively). This relationship was not found in women. Conclusion: Increased cancer risks from low-level radiation exposure within the TMI cohort were small and mostly statistically non-significant. However, additional

  2. High spectral resolution reflectance spectroscopy of minerals

    NASA Technical Reports Server (NTRS)

    Clark, Roger N.; King, Trude V. V.; Klejwa, Matthew; Swayze, Gregg A.; Vergo, Norma

    1990-01-01

    The reflectance spectra of minerals are studied as a function of spectral resolution in the range from 0.2 to 3.0 microns. Selected absorption bands were studied at resolving powers as high as 2240. At resolving powers of approximately 1000, many OH-bearing minerals show diagnostic sharp absorptions at the resolution limit. At low resolution, some minerals may not be distinguishable, but as the resolution is increased, most can be easily identified. As the resolution is increased, many minerals show fine structure, particularly in the OH-stretching overtone region near 1.4 micron. The fine structure can enhance the ability to discriminate between minerals, and in some cases the fine structure can be used to determine elemental composition.

  3. Ariel - Highest Resolution Color Picture

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The complex terrain of Ariel is viewed in this image, the best Voyager 2 color picture of the Uranian moon. The individual photos used to construct this composite were taken Jan. 24, 1986, from a distance of 170,000 kilometers (105,000 miles. Voyager captured this view of Ariel's southern hemisphere through the green, blue and violet filters of the narrow-angle camera; the resolution is about 3 km (2 mi). Most of the visible surface consists of relatively intensely cratered terrain transected by fault scarps and fault-bounded valleys (graben). Some of the largest valleys, which can be seen near the terminator (at right), are partly filled with younger deposits that are less heavily cratered. Bright spots near the limb and toward the left are chiefly the rims of small craters. Most of the brightly rimmed craters are too small to be resolved here, although one about 30 km (20 mi) in diameter can be easily distinguished near the center. These bright-rim craters, though the youngest features on Ariel, probably have formed over a long span of geological time. Although Ariel has a diameter of only about 1,200 km (750 mi), it has clearly experienced a great deal of geological activity in the past. The Voyager project is managed for NASA by the Jet Propulsion Laboratory.

  4. Heat stress control in the TMI-2 (Three Mile Island Unit 2) defueling and decontamination activities

    SciTech Connect

    Schork, J.S.; Parfitt, B.A.

    1988-01-01

    During the initial stages of the Three Mile Island Unit 2 (TMI-2) defueling and decontamination activities for the reactor building, it was realized that the high levels of loose radioactive contamination would require the use of extensive protective clothing by entry personnel. While there was no doubt that layered protective clothing protects workers from becoming contaminated, it was recognized that these same layers of clothing would impose a very significant heat stress burden. To prevent the potentially serious consequences of a severe reaction to heat stress by workers in the hostile environment of the TMI-2 reactor building and yet maintain the reasonable work productivity necessary to perform the recovery adequately, an effective program of controlling worker exposure to heat stress had to be developed. Body-cooling devices produce a flow of cool air, which is introduced close to the skin to remove body heat through convection and increased sweat evaporation. The cooling effect produced by the Vortex tube successfully protected the workers from heat stress, however, there were several logistical and operational problems that hindered extensive use of these devices. The last type of cooling garment examined was the frozen water garment (FWG) developed by Elizier Kamon at the Pennsylvania State University as part of an Electric Power Research Institute research grant. Personal protection, i.e., body cooling, engineering controls, and administrative controls, have been implemented successfully.

  5. Vehicle fuel economy and vehicle miles traveled: An empirical investigation of Jevons' Paradox

    NASA Astrophysics Data System (ADS)

    Munyon, Vinola Vincent

    There has been, in recent decades, a concerted effort to promote energy efficiency as a means to reduce energy consumption, along the supply and demand sides. The general thesis is that, ceteris paribus, an increase in energy efficiency would lead to a decrease in the consumption of the good or service rendered efficient. This is in opposition to Jevons' Paradox which states that "It is wholly a confusion of ideas to suppose that the economical use of fuel is equivalent to a diminished consumption. The very contrary is the truth..." (Jevons, 1865). While many studies have applied Jevons' Paradox to various sectors to estimate rebound effects, few have examined if Jevons' Paradox holds when all available factors that could affect consumption of an efficient good/service are controlled for. This study hoped to fill that gap in literature. The study looked at vehicle fuel economy and vehicle miles travelled (VMT) and examined if, all else being equal, a vehicle that was more fuel efficient accrued greater VMT. Using data from the National Household Travel Survey (NHTS, 2009), a multivariate regression model was built (N = 82,485) controlling for driver, household and vehicle attributes. The findings indicated that, at the microlevel, Jevons' Paradox does hold true; a 1% increase in fuel efficiency was associated with a 1.2% increase in VMT.

  6. Estimating commercial truck VMT (vehicle miles of travel) of interstate motor carriers: Data evaluation

    SciTech Connect

    Hu, P.S.; Wright, T.; Miaou, Shaw-Pin; Beal, D.J.; Davis, S.C.; Tennessee Univ., Knoxville, TN )

    1989-11-01

    This memorandum summarizes the evaluation results of six data sources in terms of their ability to estimate the number of commercial trucks operating in interstate commerce and their vehicle miles of travel (VMT) by carrier type and by state. The six data sources are: (1) Truck Inventory and Use Survey (TIUS) from the Bureau of the Census, (2) nationwide truck activity and commodity survey (NTACS) from the Bureau of the Census, (3) National Truck Trip Information Survey (NTTIS) from the University of Michigan Transportation Research Institute (UMTRI), (4) highway performance monitoring system (HPMS) from the Federal Highway Administration (FHWA), Department of Transportation, (5) state fuel tax reports from each individual state and the international fuel tax agreement (IFTA), and (6) International Registration Plan (IRP) of the American Association of Motor Vehicle Administrators (AAMVA). TIUS, NTACS, and NTTIS are designed to provide data on the physical and operational characteristics of the Nation's truck population (or sub-population); HPMS is implemented to collect information on the physical and usage characteristics of various highway systems; and state fuel tax reports and IRP are tax-oriented registrations. 16 figs., 13 tabs.

  7. Identity versus determinism: Émile Meyerson's neo-Kantian interpretation of the quantum theory

    NASA Astrophysics Data System (ADS)

    Mills, M. Anthony

    2014-08-01

    Despite the praise his writing garnered during his lifetime, e.g., from readers such as Einstein and de Broglie, Émile Meyerson has been largely forgotten. The rich tradition of French épistémologie has recently been taken up in some Anglo-American scholarship, but Meyerson-who popularized the term épistémologie through his historical method of analyzing science, and criticized positivism long before Quine and Kuhn-remains overlooked. If Meyerson is remembered at all, it is as a historian of classical science. This paper attempts to rectify both states of affairs by explicating one of Meyerson's last and untranslated works, Réel et déterminisme dans la théorie quantique, an opuscule on quantum physics. I provide an overview of Meyerson's philosophy, his critique of Max Planck's interpretation of quantum physics, and then outline and evaluate Meyerson's neo-Kantian alternative. I then compare and contrast this interpretation with Cassirer's neo-Kantian program. Finally I show that, while Meyerson believes the revolutionary new physics requires "profoundly" modifying our conception of reality, ultimately, he thinks, it secures the legitimacy of his thesis: that science seeks explanations in the form of what he calls "identification." I hope my research will enable a more general and systematic engagement with Meyerson's work, especially with a view to assessing its viability as a philosophical method today.

  8. Emergency Preparedness in the 10-Mile Emergency Planning Zone Surrounding Nuclear Power Plants

    PubMed Central

    Adalja, Amesh A.; Sell, Tara Kirk; Ravi, Sanjana J.; Minton, Katie; Morhard, Ryan

    2015-01-01

    Objectives Each of the nuclear power plants in the US is encircled by an Emergency Planning Zone (EPZ). Within each EPZ, government officials, utility professionals, emergency managers, and public health practitioners collectively conduct extensive planning, exercises, and outreach to better protect their communities in the event of a nuclear accident. Our objective was to conduct a cross-sectional study of off-site public health preparedness within EPZs to better understand the dynamics of nuclear preparedness and uncover lessons for all-hazards preparedness. Methods Using a qualitative, interview-based method, we consulted 120 county emergency managers, state health preparedness officers, state radiation health officials, and industry officials from 17 EPZs in ten different states. Results Interviewees reflected that EPZ emergency preparedness is generally robust, results from strong public-private partnership between nuclear plants and emergency management agencies, and enhances all-hazard preparedness. However, there exist a few areas which merit further study and improvement. These areas include cross-state coordination, digital public communication, and optimizing the level of public education within EPZs. Conclusions This first-of-its-kind study provides a cross-sectional snapshot of emergency preparedness in the 10-mile EPZ surrounding nuclear power plants. PMID:26692825

  9. Spontaneous decline in exercise-induced proteinuria during a 100-mile triathlon.

    PubMed

    Edes, T E; Shah, J H; Thornton, W H

    1990-09-01

    To study the effect of prolonged exercise on glomerular permeability and proteinuria, we collected serial urine samples from six athletes during a 100-mile triathlon. Urine collected just before, at the midpoint of, and immediately after the race was analyzed for creatinine by an automated chemistry analyzer, pack method, and for microalbumin by radioimmunoassay. By midrace, the urinary albumin-creatinine ratio increased from the prerace mean +/- SEM of 3.5 +/- 0.5 to 38.3 +/- 11.7 mg/g. The ratio then declined to 12.5 +/- 2.7 mg/g by the end of the race (P less than .04). Similarly, the urinary albumin level increased significantly from 5.9 +/- 0.7 to 80.5 +/- 26.8 micrograms/mL by midrace, followed by a decline to 39.2 +/- 12.9 micrograms/mL. The initial increase in albuminuria was expected and reflects the increase in exercise-induced cardiac output and glomerular permeability. The subsequent decline in albuminuria and albumin-creatinine ratio, despite continued exercise, was unexpected and indicates a decrease in glomerular permeability. Further study is warranted to determine the mechanism of this apparently protective renal response to prolonged exercise.

  10. Radiation hazards in children - lessons from Chernobyl, Three Mile Island and Fukushima.

    PubMed

    Fushiki, Shinji

    2013-03-01

    On March 11, 2011, Japan was hit by the Great East Japan Earthquake followed by the Fukushima Daiichi Nuclear Disaster. Firstly, this review focuses on what happened after the accidents at the Three Mile Island nuclear power station in 1979 and the Chernobyl nuclear power plant in 1986, in terms of the effects of these incidents on health. The most critical issue when considering the effects of radiation on the health of children was the increase of thyroid cancer, as clearly demonstrated among people who were children or adolescence at the time of the Chernobyl accident. Therefore, in the early days after a nuclear accident, the primary concern should be efforts to prevent the exposure of children to radioactive iodine through inhalation and ingestion, because radioactive iodine preferentially accumulates in the thyroid. In the longer term, another concern is exposure to radionuclides with long half-lives, including cesium137 and cesium134, with physical half-lives of 30 and 2 years, respectively. Secondly, fetal radiation risks and radiobiological studies on low-level radiation are briefly reviewed, with reference to the effects upon the developing brain. A fetal dose of 100 mSv may increase the risk of an effect on brain development, especially neuronal migration, based upon the results of experiments with rodents. Finally, this review proposes that research on the health effects of low level radiation should be prioritized so that accurate information on the effects of radiation can be disseminated and prevent the prevalence of unnecessary fear lacking scientific justification.

  11. Human factors in surgery: from Three Mile Island to the operating room.

    PubMed

    D'Addessi, Alessandro; Bongiovanni, Luca; Volpe, Andrea; Pinto, Francesco; Bassi, PierFrancesco

    2009-01-01

    Human factors is a definition that includes the science of understanding the properties of human capability, the application of this understanding to the design and development of systems and services, the art of ensuring their successful applications to a program. The field of human factors traces its origins to the Second World War, but Three Mile Island has been the best example of how groups of people react and make decisions under stress: this nuclear accident was exacerbated by wrong decisions made because the operators were overwhelmed with irrelevant, misleading or incorrect information. Errors and their nature are the same in all human activities. The predisposition for error is so intrinsic to human nature that scientifically it is best considered as inherently biologic. The causes of error in medical care may not be easily generalized. Surgery differs in important ways: most errors occur in the operating room and are technical in nature. Commonly, surgical error has been thought of as the consequence of lack of skill or ability, and is the result of thoughtless actions. Moreover the 'operating theatre' has a unique set of team dynamics: professionals from multiple disciplines are required to work in a closely coordinated fashion. This complex environment provides multiple opportunities for unclear communication, clashing motivations, errors arising not from technical incompetence but from poor interpersonal skills. Surgeons have to work closely with human factors specialists in future studies. By improving processes already in place in many operating rooms, safety will be enhanced and quality increased.

  12. Historical summary of the Three Mile Island Unit 2 core debris transportation campaign

    SciTech Connect

    Schmitt, R.C.; Tyacke, M.J.; Quinn, G.J.

    1993-03-01

    Transport of the damaged core materials from the Unit 2 reactor of the Three Mile Island Nuclear Power Station (TMI-2) to the Idaho National Engineering Laboratory (INEL) for examination and storage presented many technical and institutional challenges, including assessing the ability to transport the damaged core; removing and packaging core debris in ways suitable for transport; developing a transport package that could both meet Federal regulations and interface with the facilities at TMI-2 and the INEL; and developing a transport plan, support logistics, and public communications channels suited to the task. This report is a historical summary of how the US Department of Energy addressed those challenges and transported, received, and stored the TMI-2 core debris at the INEL. Subjects discussed include preparations for transport, loading at TMI-2, institutional issues, transport operations, receipt and storage at the INEL, governmental inquiries/investigations, and lessons learned. Because of public attention focused on the TMI-2 Core Debris Transport Program, the exchange of information between the program and public was extensive. This exchange is a focus for parts of this report to explain why various operations were conducted as they were and why certain technical approaches were employed. And, because of that exchange, the program may have contributed to a better public understanding of such actions and may contribute to planning and execution of similar future actions.

  13. Photographer : JPL Range : 312, 000 kilometers (195,000 miles) This photo of Ganymede (Ice Giant)

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Photographer : JPL Range : 312, 000 kilometers (195,000 miles) This photo of Ganymede (Ice Giant) was taken from Voyager 2 and shows features down to about 5 to 6 kilometers across. Different types of terrain common on Ganymede's surface are visible. The boundary of the largest region of dark ancient terrain on Ganymede can be seen to the east (right), revealing some of the light linear features which may be all that remains of a large ancient impact structure similar to the large ring structure on Callisto. The broad light regions running through the image are the typical grooved structures seen within another example of what might be evidence of large scale lateral motion in Ganymede's crust. The band of grooved terrain (about 100 kilometers wide) in this region appears to be offset by 50 kilometers or more on the left hand edge by a linear feature perpendicular to it. A feature similar to this one was previously discovered by Voyager 1. These are the first clear examples of strike-slip style faulting on any planet other than Earth. Many examples of craters of all ages can be seen in this image, ranging from fresh, bright ray craters to large, subdued circular markings thought to be the 'scars' of large ancient impacts that have been flatteded by glacier-like flows.

  14. NRC plan for cleanup operations at Three Mile Island Unit 2. Rev. 2

    SciTech Connect

    Masnik, M.T.; Snyder, B.J.

    1984-03-01

    This report updates a plan that defines NRC's role in cleanup operations at Three Mile Island Unit 2 (TMI-2) and outlines NRC's regulatory responsibilities in fulfilling this role. These responsibilities include reviewing and approving General Public Utilities Nuclear Corporation (the licensee) proposals for cleanup actions, overseeing the licensee's implementation of approved activities, coordinating wih other federal and state governmental agencies on their activities in the cleanup, and informing local officials and the public about the status of the cleanup. Since the initial issuance of this NRC Plan in July 1980, this office has issued the Final NRC Programmatic Environmental Impact Statement (PEIS) related to the entire TMI-2 cleanup and a draft Supplement to the PEIS related to occupational radiation exposure. Additionally, a number of developments have occurred which will have an impact on the course of cleanup operations. This revision provides a discussion of these developments, specifically in the areas of the functinal role of the NRC in cleanup operations, the cleanup schedule, and the current status of the cleanup. The plan also discusses NRC's perceived role in future cleanup activities.

  15. A comparison between conventional and LANDSAT based hydrologic modeling: The Four Mile Run case study

    NASA Technical Reports Server (NTRS)

    Ragan, R. M.; Jackson, T. J.; Fitch, W. N.; Shubinski, R. P.

    1976-01-01

    Models designed to support the hydrologic studies associated with urban water resources planning require input parameters that are defined in terms of land cover. Estimating the land cover is a difficult and expensive task when drainage areas larger than a few sq. km are involved. Conventional and LANDSAT based methods for estimating the land cover based input parameters required by hydrologic planning models were compared in a case study of the 50.5 sq. km (19.5 sq. mi) Four Mile Run Watershed in Virginia. Results of the study indicate that the LANDSAT based approach is highly cost effective for planning model studies. The conventional approach to define inputs was based on 1:3600 aerial photos, required 110 man-days and a total cost of $14,000. The LANDSAT based approach required 6.9 man-days and cost $2,350. The conventional and LANDSAT based models gave similar results relative to discharges and estimated annual damages expected from no flood control, channelization, and detention storage alternatives.

  16. Comprehensive Analysis of MILE Gene Expression Data Set Advances Discovery of Leukaemia Type and Subtype Biomarkers.

    PubMed

    Labaj, Wojciech; Papiez, Anna; Polanski, Andrzej; Polanska, Joanna

    2017-03-01

    Large collections of data in studies on cancer such as leukaemia provoke the necessity of applying tailored analysis algorithms to ensure supreme information extraction. In this work, a custom-fit pipeline is demonstrated for thorough investigation of the voluminous MILE gene expression data set. Three analyses are accomplished, each for gaining a deeper understanding of the processes underlying leukaemia types and subtypes. First, the main disease groups are tested for differential expression against the healthy control as in a standard case-control study. Here, the basic knowledge on molecular mechanisms is confirmed quantitatively and by literature references. Second, pairwise comparison testing is performed for juxtaposing the main leukaemia types among each other. In this case by means of the Dice coefficient similarity measure the general relations are pointed out. Moreover, lists of candidate main leukaemia group biomarkers are proposed. Finally, with this approach being successful, the third analysis provides insight into all of the studied subtypes, followed by the emergence of four leukaemia subtype biomarkers. In addition, the class enhanced DEG signature obtained on the basis of novel pipeline processing leads to significantly better classification power of multi-class data classifiers. The developed methodology consisting of batch effect adjustment, adaptive noise and feature filtration coupled with adequate statistical testing and biomarker definition proves to be an effective approach towards knowledge discovery in high-throughput molecular biology experiments.

  17. Broadband reflectance spectroscopy for establishing a quantitative metric of vascular leak using the Miles assay

    NASA Astrophysics Data System (ADS)

    McMurdy, John; Reichner, Jonathan; Mathews, Zara; Markey, Mary; Intwala, Sunny; Crawford, Gregory

    2009-09-01

    Monitoring the physiological effects of biological mediators on vascular permeability is important for identifying potential targets for antivascular leak therapy. This therapy is relevant to treatments for pulmonary edema and other disorders. Current methods of quantifying vascular leak are in vitro and do not allow repeated measurement of the same animal. Using an in vivo diffuse reflectance optical method allows pharmacokinetic analysis of candidate antileak molecules. Here, vascular leak is assessed in mice and rats by using the Miles assay and introducing irritation both topically using mustard oil and intradermally using vascular endothelial growth factor (VEGF). The severity of the leak is assessed using broadband diffuse reflectance spectroscopy with a fiber reflectance probe. Postprocessing techniques are applied to extract an artificial quantitative metric of leak from reflectance spectra at vascular leak sites on the skin of the animal. This leak metric is calculated with respect to elapsed time from irritation in both mustard oil and VEGF treatments on mice and VEGF treatments on rats, showing a repeatable increase in leak metric with leak severity. Furthermore, effects of pressure on the leak metric are observed to have minimal effect on the reflectance spectra, while spatial positioning showed spatially nonuniform leak sites.

  18. Characterization of solids in the Three Mile Island Unit 2 reactor defueling water

    SciTech Connect

    Campbell, D. O.

    1987-12-01

    Because of the impact of poor water clarity on defueling operations at the Three Mile Island Unit 2 Nuclear Power Station, a study was undertaken to characterize suspended particulates in the reactor defueling water. The examination included cascade filtration through Nuclepore filters of progressively smaller pore sizes, using three water samples obtained at different times and after varying degrees of clarification. The solids collected on the filters were examined with a scanning electron microscope and analyzed with energy-dispersive x-ray fluorescence. A wide variety of solids was observed, and 26 elements were detected. These included all the materials expected from the reactor system (uranium, zirconium, silver, cadmium, indium, iron, chromium, and nickel), chemicals and zeolites used to decontaminate the water (aluminum, silicon, sodium), common impurities (potassium, chlorine, sulfur, magnesium, calcium, and others), as well as some unexpected metals (molybdenum, manganese, bromine, and lead). There was also evidence for the presence of organic material. A diverse assortment of particles with widely varying surface properties was found to be present.

  19. Lessons learned from the Three Mile Island Unit 2 Advisory Panel

    SciTech Connect

    Lach, D.; Bolton, P.; Durbin, N.; Harty, R.

    1994-08-01

    In response to public concern about the cleanup of the Three Mile Island, Unit 2 (TMI-2) facility after an accident on March 28, 1979 involving a loss of reactor coolant and subsequent damage to the reactor fuel, twelve citizens were asked to serve on an independent Advisory Panel to consult with the Nuclear Regulatory Commission (NRC) on the decontamination and cleanup of the facility. The panel met 78 times over a period of thirteen years, holding public meetings in the vicinity of TMI-2 and meeting regularly with NRC Commissioners in Washington, DC. This report describes the results of a project designed to identify and describe the lessons learned from the Advisory Panel and place those lessons in the context of what we generally know about citizen advisory groups. A summary of the empirical literature on citizen advisory panels is followed by a brief history of the TMI-2 Advisory Panel. The body of the report contains the analysis of the lessons learned, preliminary conclusions about the effectiveness of the Panel, and implications for the NRC in the use of advisory panels. Data for the report include meeting transcripts and interviews with past and present Panel participants.

  20. Media exposure in children one hundred miles from a terrorist bombing.

    PubMed

    Pfefferbaum, Betty; Seale, Thomas W; Brandt, Edward N; Pfefferbaum, Rose L; Doughty, Debby E; Rainwater, Scott M

    2003-03-01

    This study assessed indirect interpersonal exposure to the 1995 Oklahoma City bombing, broadcast and print media exposure in the aftermath of the explosion, emotional reactions to media coverage, and posttraumatic stress reactions in children distant from the explosion. A survey was administered to 88 sixth-grade students in the public middle school in a community 100 miles from Oklahoma City 2 years after the bombing. Many children reported indirect interpersonal exposure and most reported bomb-related media exposure. Print media exposure was more strongly associated with enduring posttraumatic stress than broadcast exposure. Indirect interpersonal exposure and the interaction of media exposure with emotional reaction to media coverage in the aftermath of the explosion each predicted ongoing posttraumatic stress. The results suggest that children may have lingering reactions to highly publicized terrorist incidents. Concern about the influence of television viewing has long been proclaimed. This study implicates print media exposure as well. Media exposure to terrorist incidents, therefore, should be monitored and those working with children should assess exposure and stress even in children not directly impacted.

  1. Definitional Hegemony as a Public Relations Strategy: The Rhetoric of the Nuclear Power Industry after Three Mile Island.

    ERIC Educational Resources Information Center

    Dionisopoulos, George N.; Crable, Richard E.

    1988-01-01

    Examines (1) definitional hegemony as one of several rhetorical options available to issue managers; (2) the post-accident rhetorical context of the Three Mile Island nuclear crisis; and (3) the specific strategies utilized to deal with this crisis. Assesses the nuclear industry's public relations efforts. (MS)

  2. 49 CFR 228.103 - Approval procedure: construction within one-half mile (2,640 feet) (804 meters).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... RAILROAD EMPLOYEES Construction of Employee Sleeping Quarters § 228.103 Approval procedure: construction... construction or reconstruction of sleeping quarters subject to this subpart and which is considering a site... construction or reconstruction of sleeping quarters within one-half mile shall be subject to the...

  3. 49 CFR 228.103 - Approval procedure: construction within one-half mile (2,640 feet) (804 meters).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... RAILROAD EMPLOYEES Construction of Employee Sleeping Quarters § 228.103 Approval procedure: construction... construction or reconstruction of sleeping quarters subject to this subpart and which is considering a site... construction or reconstruction of sleeping quarters within one-half mile shall be subject to the...

  4. The Effects of Running Club Membership on Fourth Graders' Achievement of Connecticut State Standard for the Mile Run

    ERIC Educational Resources Information Center

    Foshay, John D.; Patterson, Melissa

    2010-01-01

    The purpose of this study was to investigate the effects of a running club on the mile run times of fourth grade students. The study was conducted in a suburban elementary school setting in central Connecticut with a student body of 400. The participants for the study included 59 fourth grade students, 30 of whom were boys and 29 of whom were…

  5. Walter Miles and his research on low dose alcohol (1914-1924): shifting the emphasis from intoxication to impairment.

    PubMed

    Goodwin, C James

    2014-11-01

    During his tenure (1914-1922) as a research scientist at Boston's Carnegie Nutrition Laboratory, Walter Miles (1885-1978) conducted important and methodologically sophisticated experiments on the psychological effects of low dose (2.75% by weight) alcohol. The research was important because it represented a shift in strategy away from examining the effects of large amounts of alcohol to determine the consequences of alcohol intoxication. Although the amount of alcohol ingested by his subjects was small, Miles was nonetheless able to demonstrate consistent deficits in several types of motor performance. Miles became an acknowledged national expert on the topic of alcohol and its behavioral consequences, and although he was unable to influence the debate that led to repealing National Prohibition in the early 1930s, his research had relevance for an issue that was emerging in the 1930s-the problem of the alcohol-impaired driver. Miles added a scientific and respected voice to the developing momentum for a societal response to the impaired driving question.

  6. Assessment report on the effects of waste dumping in 106-mile ocean waste disposal site: dumpsite evaluation report

    SciTech Connect

    Not Available

    1981-05-01

    Individual investigations carried out under NOAA funding by various Federal and university scientists are summarized. Field and laboratory studies of the heavy and transition metals in the major wastes dumped at 106-Mile Site are emphasized. Field and laboratory studies of the effects of the wastes on bacteria, plankton, fish eggs, and fish are considered.

  7. First report of anthracnose of mile-a-minute (Persicaria perfoliata) caused by Colletotrichum gloeosporioides in Turkey

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Mile-a-minute (Persicaria perfoliata (L.) H. Gross; family Polygonaceae) is an exotic annual barbed vine that is now invasive in the northeastern USA, Mississippi, and Oregon and is a target of biological control efforts. In July, 2010, diseased P. perfoliata plants were found along the Firtina Rive...

  8. 77 FR 57085 - Mobility Fund Phase I Auction; Release of Files with Recalculated Road Miles for Auction 901...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... COMMISSION Mobility Fund Phase I Auction; Release of Files with Recalculated Road Miles for Auction 901; Mock... updated data files of census blocks eligible for the Mobility Fund Phase I support to be offered in Auction 901, which is to be held on September 27, 2012, and the change of the mock auction date...

  9. Analysis of soil and water at the Four Mile Creek seepline near the F- and H-Areas of SRS

    SciTech Connect

    Haselow, J.S.

    2000-05-24

    Several soil and water samples were collected along the Four Mile Creek (FMC) seepline at the F and H Areas of the Savannah River Site. The samples were analyzed for concentrations of metals, radionuclides, and inorganic constituents. The results of the analyses are summarized for the soil and water samples.

  10. Policy and Persistence: An Exploratory Mixed Methods Case Study of "Last Mile" Students at Portland State University

    ERIC Educational Resources Information Center

    Wubbold, Joseph Mark

    2012-01-01

    In an extension of educational attainment research, this exploratory mixed- methods case study examines the influence of institutional policies on the behavior of five cohorts (n = 925) of traditional first time, full time (FTFT) freshmen--called "Last Mile" students--at one urban research university located in the Pacific Northwest.…

  11. Emulation of Equal Open Access and Competition Creation in the Wireline Telecommunications Local and Last Mile Market Segments

    ERIC Educational Resources Information Center

    Van Epps, Daniel L.

    2013-01-01

    Expanded telecommunications was deemed a serious need for end users. The "Local Market" and "Last Mile" market segments have largely consolidated into "natural utilities". Competition and access problems occur if new providers enter the local market and desire competitive access and service to end users. Local and…

  12. NGEE Arctic Plant Traits: Soil Temperature and Moisture, Kougarok Road Mile Marker 64, Seward Peninsula, Alaska, beginning 2016

    DOE Data Explorer

    Colleen Iversen; Verity Salmon; Amy Breen; Holly Vander Stel; Stan Wullschleger

    2017-03-10

    Data includes soil temperature and soil moisture measured at the Kougarok hill slope located at Kougarok Road, Mile Marker 64. Most measurements are from monitoring stations with permanently installed probes though the data also includes single point measurements from handheld devices. Data collection began in July 2016 and is ongoing. Data upload will be completed March 2017.

  13. 75 FR 67216 - Regulated Navigation Area; Greenville Bridge Demolition, Lower Mississippi River Mile 531.3, AR, MS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... required demolition of the old bridge structure can continue under the applicable contract and the... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA11 Regulated Navigation Area; Greenville Bridge Demolition... demolition of the Greenville Bridge, Lower Mississippi River Mile 531.3. Additionally, vessels will not...

  14. 78 FR 4879 - Nine Mile Point 3 Nuclear Project, LLC and UniStar Nuclear Operating Services, LLC Combined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... COMMISSION Nine Mile Point 3 Nuclear Project, LLC and UniStar Nuclear Operating Services, LLC Combined... Nuclear Project, LLC, and UniStar Nuclear Operating Services, LLC (UniStar), submitted a Combined License...) application for UniStar's Calvert Cliffs Nuclear Power Plant, Unit 3 (CCNPP3). The NRC docketed the...

  15. 49 CFR 228.103 - Approval procedure: construction within one-half mile (2,640 feet) (804 meters).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... RAILROAD EMPLOYEES; RECORDKEEPING AND REPORTING; SLEEPING QUARTERS Construction of Railroad-Provided Sleeping Quarters § 228.103 Approval procedure: construction within one-half mile (2,640 feet) (804 meters). (a) A common carrier that has developed plans for the construction or reconstruction of...

  16. 49 CFR 228.103 - Approval procedure: construction within one-half mile (2,640 feet) (804 meters).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... RAILROAD EMPLOYEES; RECORDKEEPING AND REPORTING; SLEEPING QUARTERS Construction of Railroad-Provided Sleeping Quarters § 228.103 Approval procedure: construction within one-half mile (2,640 feet) (804 meters). (a) A common carrier that has developed plans for the construction or reconstruction of...

  17. 49 CFR 228.103 - Approval procedure: construction within one-half mile (2,640 feet) (804 meters).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... RAILROAD EMPLOYEES; RECORDKEEPING AND REPORTING; SLEEPING QUARTERS Construction of Railroad-Provided Sleeping Quarters § 228.103 Approval procedure: construction within one-half mile (2,640 feet) (804 meters). (a) A common carrier that has developed plans for the construction or reconstruction of...

  18. [Fragments of a correspondence between the Parisian pharmacist Émile Vial and the Dutch painter Johan-Barthold Jongkind].

    PubMed

    Devaux, Guy

    2016-03-01

    We study a series of exchanged original letters between the Parisian pharmacist art lover Émile Vial (1833-1917) and the Dutch painter Johan-Barthold Jongkind (1819 - 1891) from april 13th, 1876 till February 1th, 1887.

  19. 77 FR 65816 - Safety Zone; Large Cruise Ships; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-31

    ..., Southwest Pass Sea Buoy to Mile Marker 96.0; New Orleans, LA AGENCY: Coast Guard, DHS. ACTION: Final rule..., and the Southwest Pass Sea Buoy. The moving safety zone extends from bank to bank encompassing one... marker 96.0, and the Southwest Pass Sea Buoy to address the increasing risk to safe navigation. For...

  20. Radiation release and health effects lessons from the Three Mile Island incident: assessment of objective risks for emergency preparedness planning

    SciTech Connect

    Berger, C.D.; Mynatt, F.R.

    1980-01-01

    The accepted theories of radiation health effects are briefly discussed so that the Three Mile Island health effects estimations can be better understood. The author recommends that emergency response planners weigh the objective risks rather than the perceived risks of low-level radiation against those associated with evacuation of large population zones before a final plan is put into effect. (ACR)

  1. Radiation release and health effects lessons from the Three Mile Island accident. Application to emergency response planning

    SciTech Connect

    Mynatt, F.R.; Berger, C.D.

    1980-11-21

    The Three Mile Island-2 accident and the ORNL response are discussed briefly. Three documents are reviewed in relation to emergency response planning for the Zimmer Nuclear Plant: NUREG-0610, NUREG-0654, and the Sequoyah emergency response plan. Distribution of potassium iodide tablets is not recommended. (DLC)

  2. Agreement between VO[subscript 2peak] Predicted from PACER and One-Mile Run Time-Equated Laps

    ERIC Educational Resources Information Center

    Saint-Maurice, Pedro F.; Anderson, Katelin; Bai, Yang; Welk, Gregory J.

    2016-01-01

    Purpose: This study examined the agreement between estimated peak oxygen consumption (VO[subscript 2peak]) obtained from the Progressive Aerobic Cardiovascular Endurance Run (PACER) fitness test and equated PACER laps derived from One-Mile Run time (MR). Methods: A sample of 680 participants (324 boys and 356 girls) in Grades 7 through 12…

  3. Analysis of soil and water at the Four Mile Creek seepline near the F H areas of SRS

    SciTech Connect

    Haselow, J.S.; Harris, M.; Looney, B.B.; Halverson, N.V.; Gladden, J.B.

    1990-06-20

    Several soil and water samples were collected along the Four Mile Creek (FMC) seepline at the F H Areas of the Savannah River Site. The samples were analyzed for concentrations of metals, radionuclides, and inorganic constituents. The results of the analyses are summarized below for the soil and water samples.

  4. Analysis of soil and water at the Four Mile Creek seepline near the F&H areas of SRS

    SciTech Connect

    Haselow, J.S.; Harris, M.; Looney, B.B.; Halverson, N.V.; Gladden, J.B.

    1990-06-20

    Several soil and water samples were collected along the Four Mile Creek (FMC) seepline at the F & H Areas of the Savannah River Site. The samples were analyzed for concentrations of metals, radionuclides, and inorganic constituents. The results of the analyses are summarized below for the soil and water samples.

  5. The Effect of Course Configuration of the Mile Run on Preference and Performance of Elementary School Runners

    ERIC Educational Resources Information Center

    Sheppard, Adam; Rubin, Daniela A.; Sherman, Clay P.; Patterson, Debra L.

    2012-01-01

    Currently, there is no standardized course configuration for the administration of the mile run/walk (MRW) test. This study assessed the effect of altering the MRW course configuration on student preference for configurations, student performance during the test, and perception of exertion after the test. Participants completed the MRW test under…

  6. Effects of outcropping groundwater from the F- and H-Area seepage basins on the distribution of fish in Four Mile Creek

    SciTech Connect

    Paller, M.H.; Storey, C.

    1990-10-01

    Four Mile Creek was electrofished during June 26--July 2, 1990 to assess the impacts of outcropping ground water form the F- and H-Area Seepage Basins on fish abundance and distribution. Number of fish species and total catch were comparable at sample stations upstream from and downstream from the outcropping zone in Four Mile Creek. Species number and composition downstream from the outcropping zone in Four Mile Creek were similar to species number and composition in unimpacted portions of Pen Branch, Steel Creek, and Meyers Branch. These findings indicate that seepage basin outcropping was not adversely affecting the Four Mile Creek fish community. 5 refs., 3 figs., 4 tabs.

  7. Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.

    PubMed

    Ramakrishnan, Boopathy; Qasba, Pradman K

    2010-05-14

    The beta1,4-galactosyltransferase-7 (beta4Gal-T7) enzyme, one of seven members of the beta4Gal-T family, transfers in the presence of manganese Gal from UDP-Gal to an acceptor sugar (xylose) that is attached to a side chain hydroxyl group of Ser/Thr residues of proteoglycan proteins. It exhibits the least protein sequence similarity with the other family members, including the well studied family member beta4Gal-T1, which, in the presence of manganese, transfers Gal from UDP-Gal to GlcNAc. We report here the crystal structure of the catalytic domain of beta4Gal-T7 from Drosophila in the presence of manganese and UDP at 1.81 A resolution. In the crystal structure, a new manganese ion-binding motif (HXH) has been observed. Superposition of the crystal structures of beta4Gal-T7 and beta4Gal-T1 shows that the catalytic pocket and the substrate-binding sites in these proteins are similar. Compared with GlcNAc, xylose has a hydroxyl group (instead of an N-acetyl group) at C2 and lacks the CH(2)OH group at C5; thus, these protein structures show significant differences in their acceptor-binding site. Modeling of xylose in the acceptor-binding site of the beta4Gal-T7 crystal structure shows that the aromatic side chain of Tyr(177) interacts strongly with the C5 atom of xylose, causing steric hindrance to any additional group at C5. Because Drosophila Cd7 has a 73% protein sequence similarity to human Cd7, the present crystal structure offers a structure-based explanation for the mutations in human Cd7 that have been linked to Ehlers-Danlos syndrome.

  8. Crystal Structure of the Catalytic Domain of Drosophila [beta]1,4-Galactosyltransferase-7

    SciTech Connect

    Ramakrishnan, Boopathy; Qasba, Pradman K.

    2010-11-03

    The {beta}1,4-galactosyltransferase-7 ({beta}4Gal-T7) enzyme, one of seven members of the {beta}4Gal-T family, transfers in the presence of manganese Gal from UDP-Gal to an acceptor sugar (xylose) that is attached to a side chain hydroxyl group of Ser/Thr residues of proteoglycan proteins. It exhibits the least protein sequence similarity with the other family members, including the well studied family member {beta}4Gal-T1, which, in the presence of manganese, transfers Gal from UDP-Gal to GlcNAc. We report here the crystal structure of the catalytic domain of {beta}4Gal-T7 from Drosophila in the presence of manganese and UDP at 1.81 {angstrom} resolution. In the crystal structure, a new manganese ion-binding motif (HXH) has been observed. Superposition of the crystal structures of {beta}4Gal-T7 and {beta}4Gal-T1 shows that the catalytic pocket and the substrate-binding sites in these proteins are similar. Compared with GlcNAc, xylose has a hydroxyl group (instead of an N-acetyl group) at C2 and lacks the CH{sub 2}OH group at C5; thus, these protein structures show significant differences in their acceptor-binding site. Modeling of xylose in the acceptor-binding site of the {beta}4Gal-T7 crystal structure shows that the aromatic side chain of Tyr{sup 177} interacts strongly with the C5 atom of xylose, causing steric hindrance to any additional group at C5. Because Drosophila Cd7 has a 73% protein sequence similarity to human Cd7, the present crystal structure offers a structure-based explanation for the mutations in human Cd7 that have been linked to Ehlers-Danlos syndrome.

  9. Methodology for Calculating Cost-per-Mile for Current and Future Vehicle Powertrain Technologies, with Projections to 2024

    SciTech Connect

    Timbario, Thomas A.; Timbario, Thomas J.; Laffen, Melissa J.; Ruth, Mark F.

    2011-04-12

    Currently, several cost-per-mile calculators exist that can provide estimates of acquisition and operating costs for consumers and fleets. However, these calculators are limited in their ability to determine the difference in cost per mile for consumer versus fleet ownership, to calculate the costs beyond one ownership period, to show the sensitivity of the cost per mile to the annual vehicle miles traveled (VMT), and to estimate future increases in operating and ownership costs. Oftentimes, these tools apply a constant percentage increase over the time period of vehicle operation, or in some cases, no increase in direct costs at all over time. A more accurate cost-per-mile calculator has been developed that allows the user to analyze these costs for both consumers and fleets. Operating costs included in the calculation tool include fuel, maintenance, tires, and repairs; ownership costs include insurance, registration, taxes and fees, depreciation, financing, and tax credits. The calculator was developed to allow simultaneous comparisons of conventional light-duty internal combustion engine (ICE) vehicles, mild and full hybrid electric vehicles (HEVs), and fuel cell vehicles (FCVs). Additionally, multiple periods of operation, as well as three different annual VMT values for both the consumer case and fleets can be investigated to the year 2024. These capabilities were included since today's “cost to own” calculators typically include the ability to evaluate only one VMT value and are limited to current model year vehicles. The calculator allows the user to select between default values or user-defined values for certain inputs including fuel cost, vehicle fuel economy, manufacturer's suggested retail price (MSRP) or invoice price, depreciation and financing rates.

  10. Genotoxicity of 1,4-benzoquinone and 1,4-naphthoquinone in relation to effects on glutathione and NAD(P)H levels in V79 cells

    SciTech Connect

    Ludewig, G.; Dogra, S.; Glatt, H. )

    1989-07-01

    1,4-Benzoquinone is cytotoxic in V79 Chinese hamster cells and induces gene mutations and micronuclei. The cell-damaging effects of quinones are usually attributed to thiol depletion, oxidation of NAD(P)H, and redox-cycling involving the formation of semiquinone radicals and reactive oxygen species. To elucidate the role of these mechanisms in the genotoxicity of 1,4-benzoquinone, the authors measured various genotoxic effects, cytotoxicity, and the levels of glutathione, NADPH, NADH, and their oxidized forms all in the same experiment. 1,4-Naphthoquinone, which does not induce gene mutations in V79 cells, was investigated for comparative reasons. The quinones had a similar effect on the levels of cofactors. Total glutathione was depleted, but levels of oxidized glutathione were slightly increased. The levels of NADPH and NADH were reduced at high concentrations of the quinones with a simultaneous increase in the levels of NADP{sup +} and NAD{sup +}. Both compounds induced micronuclei, but neither increased the frequency of sister chromatid exchange. Only 1,4-benzoquinone induced gene mutations. They conclude that (a) induction of micronuclei and glutathione depletion by the two quinones are not linked casually, (b) 1,4-benzoquinone induces gene mutations by a mechanism different from oxidative stress and glutathione depletion, and (c) glutathione does not fully protect the cells against the genotoxicity of quinones.

  11. 49 CFR 173.65 - Exceptions for Division 1.4G consumer fireworks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Exceptions for Division 1.4G consumer fireworks... Class 1 § 173.65 Exceptions for Division 1.4G consumer fireworks. (a) Notwithstanding the requirements of §§ 173.56(b), 173.56(f), 173.56(i), and 173.64, Division 1.4G consumer fireworks may be...

  12. 49 CFR 173.65 - Exceptions for Division 1.4G consumer fireworks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Exceptions for Division 1.4G consumer fireworks... Class 1 § 173.65 Exceptions for Division 1.4G consumer fireworks. (a) Notwithstanding the requirements of §§ 173.56(b), 173.56(f), 173.56(i), and 173.64, Division 1.4G consumer fireworks may be...

  13. Effect of bis-1,4-dihydropyridine in the kidney of diabetic rats.

    PubMed

    Gómez-Pliego, Raquel; Gómez-Zamudio, Jaime; Velasco-Bejarano, Benjamín; Ibarra-Barajas, Maximiliano; Villalobos-Molina, Rafael

    2013-01-01

    The in vivo effectiveness of 4-dihydropyridine (bis-1,4-DHP), a new calcium-channel blocker, as a nephroprotector in isolated perfused kidney was evaluated by determining its effects on parameters associated with renal injury in diabetic rats. Diabetes in male Wistar rats, control, diabetic, control + bis-1,4-DHP, and diabetic + bis-1,4-DHP, was induced by a single administration of STZ (55 mg·kg(-1), i.p.). In the drug-treated groups, treatment with bis-1,4-DHP (10 mg·kg(-1)·day(-1)) started one week before diabetes induction; bis-1,4-DHP was dissolved in DMSO (0.3%) and suspended in drinking water with carboxymethyl cellulose (3%). Parameters evaluated were body weight, blood glucose, albuminuria, proteinuria, creatinine, urea excretion, kidney's weight / body weight ratio, and kidney perfusion pressure in all rat groups at different times of diabetes (2, 4, 6, and 10 weeks). Kidney weight of diabetic rats significantly increased vs. control, control + bis-1,4-DHP, and diabetic + bis-1,4-DHP rats at different times of diabetes. The ratios % kidney weight / 100 g body weight were different between control, control + bis-1,4-DHP, and diabetic + bis-1,4-DHP rats vs. diabetic rats (P < 0.05). Kidney perfusion pressure was decreased by diabetes, while it was partially recovered by bis-1,4-DHP treatment in response to phenylephrine. Bis-1,4-DHP had a tendency to decrease hyperglycemia vs. diabetic rats, even though glycemia was too high as compared with controls, and it ameliorated albuminuria, creatinine, and urea excretion, suggesting a favorable effect on renal haemodynamics. Bis-1,4-DHP, by inhibiting Ca(2+) entrance, induced vasodilation in renal vascular bed and thus may have a nephroprotective effect against diabetes-induced renal dysfunction, but does not have significant impact on hyperglycemia.

  14. Biodegradation of 1,4-dioxane: effects of enzyme inducers and trichloroethylene.

    PubMed

    Hand, Steven; Wang, Baixin; Chu, Kung-Hui

    2015-07-01

    1,4-Dioxane is a groundwater contaminant and probable human carcinogen. In this study, two well-studied degradative bacteria Mycobacterium vaccae JOB5 and Rhodococcus jostii RHA1 were examined for their 1,4-dioxane degradation ability in the presence and absence of its co-contaminant, trichloroethylene (TCE), under different oxygenase-expression conditions. These two strains were precultured with R2A broth (complex nutrient medium) before supplementation with propane or 1-butanol to induce the expression of different oxygenases. Both propane- and 1-butanol-induced JOB5 and RHA1 were able to degrade 1,4-dioxane, TCE, and mixtures of 1,4-dioxane/TCE. Complete degradation of 1,4-dioxane/TCE mixture was observed only in propane-induced strain JOB5. Inhibition was observed between 1,4-dioxane and TCE for all cells. Furthermore, product toxicity caused incomplete degradation of 1,4-dioxane by 1-butanol-induced JOB5. In general, the more TCE degraded, the greater extent of product toxicity cells experienced; however, susceptibility to product toxicity was found to be both strain- and inducer-dependent. The findings of this study provide fundamental basis for developing an effective in-situ remediation method for 1,4-dioxane-contaminated ground water and the first known study of 1,4-dioxane degradation by wild-type strain RHA1.

  15. Spectral variability in the X-ray pulsar GX 1+4

    NASA Technical Reports Server (NTRS)

    Becker, R. H.; Boldt, E. A.; Holt, S. S.; Pravdo, S. H.; Rothschild, R. E.; Serlemitsos, P. J.; Swank, J. H.

    1976-01-01

    Observations of the galactic center region, hard X-ray source GX 1+4 by the GSFC X-ray spectroscopy experiment on OSO-8 confirm that GX 1+4 is a slow X-ray pulsar. The amount of absorption by cold matter in the spectrum of GX 1+4 varies significantly within a 24 hour period, behavior typical of many X-ray binary systems. The light curve for the pulsations from GX 1+4 appears to be energy dependent.

  16. Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plants

    PubMed Central

    Widhalm, Joshua R; Rhodes, David

    2016-01-01

    The 1,4-naphthoquinones (1,4-NQs) are a diverse group of natural products found in every kingdom of life. Plants, including many horticultural species, collectively synthesize hundreds of specialized 1,4-NQs with ecological roles in plant–plant (allelopathy), plant–insect and plant–microbe interactions. Numerous horticultural plants producing 1,4-NQs have also served as sources of traditional medicines for hundreds of years. As a result, horticultural species have been at the forefront of many basic studies conducted to understand the metabolism and function of specialized plant 1,4-NQs. Several 1,4-NQ natural products derived from horticultural plants have also emerged as promising scaffolds for developing new drugs. In this review, the current understanding of the core metabolic pathways leading to plant 1,4-NQs is provided with additional emphasis on downstream natural products originating from horticultural species. An overview on the biochemical mechanisms of action, both from an ecological and pharmacological perspective, of 1,4-NQs derived from horticultural plants is also provided. In addition, future directions for improving basic knowledge about plant 1,4-NQ metabolism are discussed. PMID:27688890

  17. Transcriptomic Messiness in the Venom Duct of Conus miles Contributes to Conotoxin Diversity*

    PubMed Central

    Jin, Ai-hua; Dutertre, Sébastien; Kaas, Quentin; Lavergne, Vincent; Kubala, Petra; Lewis, Richard J.; Alewood, Paul F.

    2013-01-01

    Marine cone snails have developed sophisticated chemical strategies to capture prey and defend themselves against predators. Among the vast array of bioactive molecules in their venom, peptide components called conotoxins or conopeptides dominate, with many binding with high affinity and selectivity to a broad range of cellular targets, including receptors and transporters of the nervous system. Whereas the conopeptide gene precursor organization has a conserved topology, the peptides in the venom duct are highly processed. Indeed, deep sequencing transcriptomics has uncovered on average fewer than 100 toxin gene precursors per species, whereas advanced proteomics has revealed >10-fold greater diversity at the peptide level. In the present study, second-generation sequencing technologies coupled to highly sensitive mass spectrometry methods were applied to rapidly uncover the conopeptide diversity in the venom of a worm-hunting species, Conus miles. A total of 662 putative conopeptide encoded sequences were retrieved from transcriptomic data, comprising 48 validated conotoxin sequences that clustered into 10 gene superfamilies, including 3 novel superfamilies and a novel cysteine framework (C-C-C-CCC-C-C) identified at both transcript and peptide levels. A surprisingly large number of conopeptide gene sequences were expressed at low levels, including a series of single amino acid variants, as well as sequences containing deletions and frame and stop codon shifts. Some of the toxin variants generate alternative cleavage sites, interrupted or elongated cysteine frameworks, and highly variable isoforms within families that could be identified at the peptide level. Together with the variable peptide processing identified previously, background genetic and phenotypic levels of biological messiness in venoms contribute to the hypervariability of venom peptides and their ability to evolve rapidly. PMID:24043424

  18. Radiation effects on resins and zeolites at Three Mile Island Unit II

    SciTech Connect

    Reilly, J.K.; Grant, P.J.; Quinn, G.J.; Hofstetter, K.J.

    1984-01-01

    Radiation effects on resin and zeolite used in the waste cleanup at Three Mile Island Unit II have been examined both experimentally and in-situ. Hydrogen and organic gases are generated due to absorbed radiation as a function of resin material, curie loading and residual water content. Significant oxygen scavaging was demonstrated in the organic resin liners. Hydrogen and oxygen gases in near stoichiometric quantities are generated from irradiation of residual water in inorganic zeolites. Gas generation was determined to be directly proportional to curie content but correlates poorly with residual water content in zeolite vessels. Results of the gas generation analyses of EPICOR II liners show that vessels with less than 166 curies had almost no hydrogen generated during two years of storage and therefore did not require safety measures for shipment or storage. Experimental measurements done at research laboratories predicted similar results associated with hydrogen gas generation and oxygen depletion. X-ray diffraction examinations and ion exchange capacity measurements indicated no evidence of irradiation effects on the structure or cesium exchange capacity for zeolites exposed to 10/sup 10/ rads. Darkening and damage of organic resin due to radiation has been identified. Breaking and agglomeration of the purification demineralizer resin is believed to be the result of temperature effects. No damage was identified from radiation effects on zeolite. Organic and inorganic sorbents used in the processing of contaminated waters at TMI-2 have been shown to be effective in maintaining long-term stability under high radiation conditions. The effects of radiolytic degradation have been shown by direct measurements and simulation tests and are of use in their general application throughout the industry.

  19. Peer review of the Three Mile Island Unit 2 Vessel Investigation Project metallurgical examinations

    SciTech Connect

    Bohl, R.W.; Gaydos, R.G.; Vander Voort, G.F.; Diercks, D.R.

    1994-07-01

    Fifteen samples recovered from the lower head of the Three Mile Island (TMI) Unit 2 nuclear reactor pressure vessel were subjected to detailed metallurgical examinations by the Idaho National Engineering Laboratory (INEL), with supporting work carried out by Argonne National Laboratory (ANL) and several of the European participants. These examinations determined that a portion of the lower head, a so-called elliptical ``hot spot`` measuring {approx}0.8 {times} 1 m, reached temperatures as high as 1100{degrees}C during the accident and cooled from these temperatures at {approx}10--100{degrees}C/min. The remainder of the lower head was found to have remained below the ferrite-toaustenite transformation temperature of 727{degrees}C during the accident. Because of the significance of these results and their importance to the overall analysis of the TMI accident, a panel of three outside peer reviewers, Dr. Robert W. Bohl, Mr. Richard G. Gaydos, and Mr. George F. Vander Voort, was formed to conduct an independent review of the metallurgical analyses. After a thorough review of the previous analyses and examination of photo-micrographs and actual lower head specimens, the panel determined that the conclusions resulting from the INEL study were fundamentally correct. In particular, the panel reaffirmed that four lower head samples attained temperatures as high as 1100{degrees}C, and perhaps as high as 1150--1200{degrees}C in one case, during the accident. They concluded that these samples subsequently cooled at a rate of {approx}50--125{degrees}C/min in the temperature range of 600--400{degrees}C, in good agreement with the original analysis. The reviewers also agreed that the remainder of the lower head samples had not exceeded the ferrite-to-austenite transformation temperature during the accident and suggested several refinements and alternative procedures that could have been employed in the original analysis.

  20. Comparative Analyses of Two Thermophilic Enzymes Exhibiting both β-1,4 Mannosidic and β-1,4 Glucosidic Cleavage Activities from Caldanaerobius polysaccharolyticus▿ †

    PubMed Central

    Han, Yejun; Dodd, Dylan; Hespen, Charles W.; Ohene-Adjei, Samuel; Schroeder, Charles M.; Mackie, Roderick I.; Cann, Isaac K. O.

    2010-01-01

    The hydrolysis of polysaccharides containing mannan requires endo-1,4-β-mannanase and 1,4-β-mannosidase activities. In the current report, the biochemical properties of two endo-β-1,4-mannanases (Man5A and Man5B) from Caldanaerobius polysaccharolyticus were studied. Man5A is composed of an N-terminal signal peptide (SP), a catalytic domain, two carbohydrate-binding modules (CBMs), and three surface layer homology (SLH) repeats, whereas Man5B lacks the SP, CBMs, and SLH repeats. To gain insights into how the two glycoside hydrolase family 5 (GH5) enzymes may aid the bacterium in energy acquisition and also the potential application of the two enzymes in the biofuel industry, two derivatives of Man5A (Man5A-TM1 [TM1 stands for truncational mutant 1], which lacks the SP and SLH repeats, and Man5A-TM2, which lacks the SP, CBMs, and SLH repeats) and the wild-type Man5B were biochemically analyzed. The Man5A derivatives displayed endo-1,4-β-mannanase and endo-1,4-β-glucanase activities and hydrolyzed oligosaccharides with a degree of polymerization (DP) of 4 or higher. Man5B exhibited endo-1,4-β-mannanase activity and little endo-1,4-β-glucanase activity; however, this enzyme also exhibited 1,4-β-mannosidase and cellodextrinase activities. Man5A-TM1, compared to either Man5A-TM2 or Man5B, had higher catalytic activity with soluble and insoluble polysaccharides, indicating that the CBMs enhance catalysis of Man5A. Furthermore, Man5A-TM1 acted synergistically with Man5B in the hydrolysis of β-mannan and carboxymethyl cellulose. The versatility of the two enzymes, therefore, makes them a resource for depolymerization of mannan-containing polysaccharides in the biofuel industry. Furthermore, on the basis of the biochemical and genomic data, a molecular mechanism for utilization of mannan-containing nutrients by C. polysaccharolyticus is proposed. PMID:20562312

  1. The effects of 1,4-cyclohexanediol on frozen ram spermatozoa.

    PubMed

    Quan, G B; Wu, S S; Lan, Z G; Yang, H Y; Shao, Q Y; Hong, Q H

    2013-01-01

    In order to improve the quality of frozen spermatozoa of Yunnan semi-fine wool sheep, 1, 4-cyclohexanediol (1, 4-CHD) as a synthetic ice blocker was used for cryopreservation of ram spermatozoa in this study. Briefly, following collection by electric stimulation, equilibration at 5℃ following dilution with the freezing extender, and pre-freezing in liquid nitrogen vapor, the ram spermatozoa were preserved in liquid nitrogen for one month. In addition, the effects of osmolarity of the diluting extenders used for evaluation of frozen spermatozoa quality were also assessed. The results indicated addition of 1, 4-CHD could not increase the motility of ram spermatozoa after cryopreservation and thawing. With the elevation of the concentrations of 1, 4-CHD, the motility and moving velocity of frozen ram spermatozoa showed a steady decrease. Additionally, the presence of 1, 4-CHD cannot increase the percentage of frozen spermatozoa with intact acrosome and membrane. When the isotonic binding buffer was used to dilute the thawed spermatozoa, the percentage of cells labeled with propidium iodide (PI) after cryopreservation in the presence of 1, 4-CHD was significantly higher than that of spermatozoa frozen in the absence of 1, 4-CHD (P < 0.05). However, the percentage of frozen-thawed spermatozoa with exposed PS in the presence of 1, 4-CHD was significantly less than that of spermatozoa frozen in the absence of 1, 4-CHD (P < 0.01). When the basic extenders with an osmolarity of 404mOsm, 528mOsm, 648mOsm, or 853mOsm were used to dilute the frozen-thawed spermatozoa respectively, there is no significant difference between the four groups with respect to the moving velocity and membrane integrity (P > 0.05). In conclusion, the presence of 1, 4-CHD cannot improve the motility, moving velocity, acrosome staus, and membrane integrity of frozen ram spermatozoa. However, 1, 4-CHD may inhibit apoptosis caused by freezing and thawing.

  2. 33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods... or radio contact with the Lockmaster at Murray Lock and Dam. (c) Transit of the RNA during periods...

  3. 33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods... or radio contact with the Lockmaster at Murray Lock and Dam. (c) Transit of the RNA during periods...

  4. 33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods... or radio contact with the Lockmaster at Murray Lock and Dam. (c) Transit of the RNA during periods...

  5. 33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods... or radio contact with the Lockmaster at Murray Lock and Dam. (c) Transit of the RNA during periods...

  6. 33 CFR 165.817 - Arkansas River, Mile 118.2 to 125.4, Little Rock Arkansas-regulated navigation area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... navigation area. (a) Location. The following is a regulated navigation area (RNA): The waters of the Arkansas River between mile 118.2 and mile 125.4. (b) Regulations. Transit of the RNA is limited during periods... or radio contact with the Lockmaster at Murray Lock and Dam. (c) Transit of the RNA during periods...

  7. 50 CFR Figure 1 to Subpart I of... - Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas extend beyond 3 miles offshore) and Optional.... I, Fig. 1 Figure 1 to Subpart I of Part 660—Existing California Area Closures (hatched areas...

  8. 50 CFR Figure 1 to Subpart I of... - Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas extend beyond 3 miles offshore) and Optional.... I, Fig. 1 Figure 1 to Subpart I of Part 660—Existing California Area Closures (hatched areas...

  9. 50 CFR Figure 1 to Subpart I of... - Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas extend beyond 3 miles offshore) and Optional.... I, Fig. 1 Figure 1 to Subpart I of Part 660—Existing California Area Closures (hatched areas...

  10. 50 CFR Figure 1 to Subpart I of... - Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas extend beyond 3 miles offshore) and Optional.... I, Fig. 1 Figure 1 to Subpart I of Part 660—Existing California Area Closures (hatched areas...

  11. 50 CFR Figure 1 to Subpart I of... - Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Existing California Area Closures (hatched areas extend to 3 miles offshore; cross-hatched areas extend beyond 3 miles offshore) and Optional.... I, Fig. 1 Figure 1 to Subpart I of Part 660—Existing California Area Closures (hatched areas...

  12. Sex Offender Registration: Balancing the Rights of the Individual with the Public Good--A Commentary on Comartin, Kernsmith, and Miles (2010)

    ERIC Educational Resources Information Center

    Berkowitz, Carol D.

    2010-01-01

    This article presents the author's comments on the article "Family Experiences of Young Adult Sex Offender Registration" by E. B. Comartin, P. D. Kernsmith, & P. W. Miles (2010). In the article "Family Experiences of Young Adult Sex Offender Registration", Comartin, Kernsmith, and Miles (2010) put forth a telling argument about the impact of the…

  13. 33 CFR 165.812 - Security Zones; Lower Mississippi River, Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... River, Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans, LA. 165.812 Section 165.812 Navigation..., Southwest Pass Sea Buoy to Mile Marker 96.0, New Orleans, LA. (a) Location. Within the Lower Mississippi River and Southwest Pass, moving security zones are established around all cruise ships between...

  14. 33 CFR 165.T08-0238 - Safety Zone; Cincinnati Symphony Orchestra Fireworks Displays Ohio River, Mile 460.9-461.3...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Safety Zone; Cincinnati Symphony Orchestra Fireworks Displays Ohio River, Mile 460.9-461.3, Cincinnati, OH. 165.T08-0238 Section 165.T08-0238... Fireworks Displays Ohio River, Mile 460.9-461.3, Cincinnati, OH. (a) Location. The following area is...

  15. 33 CFR 165.T11-0523 - Safety Zone; Houma Navigation Canal, From Waterway Mile Markers 19.0 to 20.0, Southwest of Bayou...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Canal, From Waterway Mile Markers 19.0 to 20.0, Southwest of Bayou Plat, Bank to Bank, Terrebonne Parish... Bayou Plat, Bank to Bank, Terrebonne Parish, LA. (a) Location. Houma Navigation Canal, from Waterway Mile Markers 19.0 to 20.0, Southwest of Bayou Plat, bank to bank, Terrebonne Parish, Louisiana....

  16. Laboratory Investigation Of Mechanisms For 1,4-Dioxane Destruction By Ozone In Water

    EPA Science Inventory

    Advances in analytical detection methods have made it possible to quantify 1,4-dioxane contamination in groundwater, even at well-characterized sites where it had not been previously detected. Although 1,4-dioxane is difficult to treat because of its chemical and physical proper...

  17. 20 CFR 1.4 - Where are other rules concerning OWCP functions found?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... functions found? 1.4 Section 1.4 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF... functions found? (a) The rules of the OWCP governing its functions under the Longshore and Harbor Workers' Compensation Act and its extensions are set forth in subchapter A of chapter VI of this title. (b) The rules...

  18. IN-SITU OXIDATION OF 1,4-DIOXANE (LABORATORY RESULTS)

    EPA Science Inventory

    Interest in the solvent stabilizer, 1,4-dioxane, is increasing because analytical detection limits have decreased indicating its presence at chlorinated volatile organic compound contaminated sites. The most common method for removing 1,4-dioxane from contaminated water is advanc...

  19. Anti-voltage-gated potassium channel Kv1.4 antibodies in myasthenia gravis.

    PubMed

    Romi, Fredrik; Suzuki, Shigeaki; Suzuki, Norihiro; Petzold, Axel; Plant, Gordon T; Gilhus, Nils Erik

    2012-07-01

    Myasthenia gravis (MG) is an autoimmune disease characterized by skeletal muscle weakness mainly caused by acetylcholine receptor antibodies. MG can be divided into generalized and ocular, and into early-onset (<50 years of age) and late-onset (≥50 years of age). Anti-Kv1.4 antibodies targeting α-subunits (Kv1.4) of the voltage-gated potassium K(+) channel occurs frequently among patients with severe MG, accounting for 18% of a Japanese MG population. The aim of this study was to characterize the clinical features and serological associations of anti-Kv1.4 antibodies in a Caucasian MG population with mild and localized MG. Serum samples from 129 Caucasian MG patients with mainly ocular symptoms were tested for the presence of anti-Kv1.4 antibodies and compared to clinical and serological parameters. There were 22 (17%) anti-Kv1.4 antibody-positive patients, most of them women with late-onset MG, and all of them with mild MG. This contrasts to the Japanese anti-Kv1.4 antibody-positive patients who suffered from severe MG with bulbar symptoms, myasthenic crisis, thymoma, myocarditis and prolonged QT time on electrocardiography, despite equal anti-Kv1.4 antibody occurrence in both populations. No other clinical or serological parameters influenced anti-Kv1.4 antibody occurrence.

  20. IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR 1,4 - DIOXANE

    EPA Science Inventory

    1,4 -Dioxane is a cyclic ether that is primarily utilized for industrial applications. These applications include 1,4 -dioxane as a solvent, reaction medium, wetting, degreasing, and dispersing agent, and for stabilization of chlorinated solvents (e.g. 1,1,1 -trichloroethane). ...