Science.gov

Sample records for 1-a commercial fusion

  1. Mirror Advanced Reactor Study (MARS). Final report. Volume 1-A. Commercial fusion electric plant

    SciTech Connect

    Donohue, M.L.; Price, M.E.

    1984-07-01

    Volume 1-A contains the following chapters: (1) plasma engineering, (2) magnets, (3) ecr heating systems, (4) anchor ion-cyclotron resonance heating system, (5) sloshing ion neutral beam, (6) end cell structure, (7) end plasma technology, (8) fueling, (9) startup ion cyclotron resonant heating systems, and (10) end cell radiation analysis. (MOW)

  2. Inertial fusion commercial power plants

    NASA Astrophysics Data System (ADS)

    Logan, B. Grant

    1994-09-01

    This presentation discusses the motivation for inertial fusion energy, a brief synopsis of five recently-completed inertial fusion power plant designs, some general conclusions drawn from these studies, and an exmaple of an IEE hydrogen synfuel plant to suggest that future fusion studies consider broadening fusion use to low-emission fuels production as well as electricity.

  3. Outlook: Scientific obstacles. [Scientific obstacles to commercial nuclear fusion

    SciTech Connect

    Not Available

    1993-01-22

    There is no question that fusion technology has come a long way. And yet commercial fusion energy seems as distant as ever. Numerous questions remain unanswered: Is magnetic fusion more promising than inertial fusion Which physical concept for a reactor is the best one Will the fully developed technology be economically competitive with other sources of energy Will fusion be as clean as promised And most fundamentally, can scientists make it work at all This article summarizes some of technological issues and hurdles facing fusion programs. Also, potential considerations are examined.

  4. LIFE: The Case for Early Commercialization of Fusion Energy

    SciTech Connect

    Anklam, T; Simon, A J; Powers, S; Meier, W R

    2010-11-30

    This paper presents the case for early commercialization of laser inertial fusion energy (LIFE). Results taken from systems modeling of the US electrical generating enterprise quantify the benefits of fusion energy in terms of carbon emission, nuclear waste and plutonium production avoidance. Sensitivity of benefits-gained to timing of market-entry is presented. These results show the importance of achieving market entry in the 2030 time frame. Economic modeling results show that fusion energy can be competitive with other low-carbon energy sources. The paper concludes with a description of the LIFE commercialization path. It proposes constructing a demonstration facility capable of continuous fusion operations within 10 to 15 years. This facility will qualify the processes and materials needed for a commercial fusion power plant.

  5. A commercial lunar helium 3 fusion power infrasructure

    NASA Astrophysics Data System (ADS)

    Sved, J.; Kulcinski, G. L.; Miley, G. H.

    1995-01-01

    The potential scenario of a commercial aneutronic fusion power economy based on Helium 3 is reviewed with recent developments in fusion grade plasma containment considered. The Spherical Inertial Electrostatic Confinement (IEC) device is a type of fusion reactor with immediate commercial applications as a small non-power reactor. Further development and growth to power reactor fusion reaction rates using Deuterium and Helium 3 offers the potential practical solution to fusion power. Recovery of the lunar Helium 3 inventory for export to power utility customers will require the build-up of a cis-lunar industrial infrastructure. Space transport capacity will be obliged to grow rapidly to support several thousand tons of cargo delivery to the lunar surface per year. A highly reusable, low operations cost cis-lunar transport infrastructure and lunar surface industrial activity will be made more practical by the availability of IEC fusion power units that are intrinsically low mass and compatible with space transport.

  6. Should the US abandon efforts to develop commercial fusion power

    SciTech Connect

    Kay, W.D.; Kinter, E.E.

    1993-01-22

    This article presents viewpoints and rationale for continuing and disbanding the US efforts to develop commercial fusion power. The views of W.D. Kay, an assistant professor of political science at Northeastern University, are presented regarding - yes, abandon efforts. Meanwhile, the views of Edwin Keutes, former director of the Magnetic Fusion Program for DOE, are presented for continued development.

  7. A Pilot Plant: The Fastest Path to Commercial Fusion Energy

    SciTech Connect

    Robert J. Goldston

    2010-03-03

    Considerable effort has been dedicated to determining the possible properties of a magneticconfinement fusion power plant, particularly in the U.S.1, Europe2 and Japan3. There has also been some effort to detail the development path to fusion energy, particularly in the U.S.4 Only limited attention has been given, in Japan5 and in China6, to the options for a specific device to form the bridge from the International Thermonuclear Experimental Reactor, ITER, to commercial fusion energy. Nor has much attention been paid, since 2003, to the synergies between magnetic and inertial fusion energy development. Here we consider, at a very high level, the possibility of a Qeng ≥ 1 Pilot Plant, with linear dimensions ~ 2/3 the linear dimensions of a commercial fusion power plant, as the needed bridge. As we examine the R&D needs for such a system we find significant synergies between the needs for the development of magnetic and inertial fusion energy.

  8. Material options for a commercial fusion reactor first wall

    SciTech Connect

    Dabiri, A.E.

    1986-05-01

    A study has been conducted to evaluate the potential of various materials for use as first walls in high-power-density commercial fusion reactors. Operating limits for each material were obtained based on a number of criteria, including maximum allowable structural temperatures, critical heat flux, ultimate tensile strength, and design-allowable stress. The results with water as a coolant indicate that a modified alloy similar to HT-9 may be a suitable candidate for low- and medium-power-density reactor first walls with neutron loads of up to 6 MW/m/sup 2/. A vanadium or copper alloy must be used for high-power-density reactors. The neutron wall load limit for vanadium alloys is about 14 MW/sup 2/, provided a suitable coating material is chosen. The extremely limited data base for radiation effects hinders any quantitative assessment of the limits for copper alloys.

  9. Commercial objectives, technology transfer, and systems analysis for fusion power development

    NASA Technical Reports Server (NTRS)

    Dean, Stephen O.

    1988-01-01

    Fusion is an inexhaustible source of energy that has the potential for economic commercial applications with excellent safety and environmental characteristics. The primary focus for the fusion energy development program is the generation of central station electricity. Fusion has the potential, however, for many other applications. The fact that a large fraction of the energy released in a DT fusion reaction is carried by high energy neutrons suggests potentially unique applications. In addition, fusion R and D will lead to new products and new markets. Each fusion application must meet certain standards of economic and safety and environmental attractiveness. For this reason, economics on the one hand, and safety and environment and licensing on the other, are the two primary criteria for setting long range commercial fusion objectives. A major function of systems analysis is to evaluate the potential of fusion against these objectives and to help guide the fusion R and D program toward practical applications. The transfer of fusion technology and skills from the national labs and universities to industry is the key to achieving the long range objective of commercial fusion applications.

  10. STARFIRE: a commercial tokamak fusion power plant study

    SciTech Connect

    Not Available

    1980-09-01

    STARFIRE is a 1200 MWe central station fusion electric power plant that utilizes a deuterium-tritium fueled tokamak reactor as a heat source. Emphasis has been placed on developing design features which will provide for simpler assembly and maintenance, and improved safety and environmental characteristics. The major features of STARFIRE include a steady-state operating mode based on continuous rf lower-hybrid current drive and auxiliary heating, solid tritium breeder material, pressurized water cooling, limiter/vacuum system for impurity control and exhaust, high tritium burnup and low vulnerable tritium inventories, superconducting EF coils outside the superconducting TF coils, fully remote maintenance, and a low-activation shield. A comprehensive conceptual design has been developed including reactor features, support facilities and a complete balance of plant. A construction schedule and cost estimate are presented, as well as study conclusions and recommendations.

  11. Tritium Breeding Blanket for a Commercial Fusion Power Plant - A System Engineering Assessment

    SciTech Connect

    Meier, Wayne R.

    2014-04-14

    The goal of developing a new source of electric power based on fusion has been pursued for decades. If successful, future fusion power plants will help meet growing world-wide demand for electric power. A key feature and selling point for fusion is that its fuel supply is widely distributed globally and virtually inexhaustible. Current world-wide research on fusion energy is focused on the deuterium-tritium (DT for short) fusion reaction since it will be the easiest to achieve in terms of the conditions (e.g., temperature, density and confinement time of the DT fuel) required to produce net energy. Over the past decades countless studies have examined various concepts for TBBs for both magnetic fusion energy (MFE) and inertial fusion energy (IFE). At this time, the key organizations involved are government sponsored research organizations world-wide. The near-term focus of the MFE community is on the development of TBB mock-ups to be tested on the ITER tokamak currently under construction in Caderache France. TBB concepts for IFE tend to be different from MFE primarily due to significantly different operating conditions and constraints. This report focuses on longer-term commercial power plants where the key stakeholders include: electric utilities, plant owner and operator, manufacturer, regulators, utility customers, and in-plant subsystems including the heat transfer and conversion systems, fuel processing system, plant safety systems, and the monitoring control systems.

  12. Radioactive waste produced by DEMO and commercial fusion reactors extrapolated from ITER and advanced data bases

    SciTech Connect

    Stacey, W.M.; Hertel, N.E.; Hoffman, E.A.

    1994-07-01

    The radioactive wastes that would be produced in demonstration (DEMO) and commercial (CFR) fusion reactors which could be extrapolated from the design data base that will be provided by ITER and its supporting R&D and from a design data base supplemented by advanced physics and advanced materials R&D programs are identified and characterized in terms of a number of possible criteria for near-surface burial. The results indicate that there is a possibility that all fusion wastes could satisfy a ``low level`` waste criterion for ``near-surface`` burial.

  13. The role of materials R&D in the development of commercial fusion power plants

    NASA Astrophysics Data System (ADS)

    Davis, J. W.

    The introduction of new materials into a commercial fusion power plant is the ultimate goal of any long range materials development program. Success requires interactive communication between the design community and materials community to ensure that the materials being developed meet the requirements of the user or customer. This communication can be in the form of participating in project meetings with the reactor designers and providing supporting data. It can also be in the form of a material properties handbook used by the designers and structural analysts. The R&D activities must also support the development of structural design criteria to ensure the reliability and long-life capability of these new materials. This paper examines the materials development issues, looks at the role of ITER and other experimental facilities in materials development, and shows how ITER can be used to develop confidence in the use of new materials in future fusion reactors.

  14. Test design description for the Fusion Materials Open Test Assembly (Fusion MOTA-2A): Volume 1A, Part 1

    SciTech Connect

    Bauer, R.E.

    1988-11-01

    This document encompasses the test requirements, hardware design, fabrication, and safety analysis for the Fusion Materials Open Test Assembly experiment for irradiation in FFTF Cycle 11 (Fusion MOTA-2A). Fusion MOTA is equally shared by the US Fusion Material (DOE), Japanese Fusion Materials (MONBUSHO), and BEATRIX-II (IEA) programs. In the interest of providing optimum use of the irradiation space in the Fusion MOTA-2A and LMR MOTA-1G, eight of the Fusion MOTA canisters will be placed in MOTA-1G and an equal number of LMR canisters placed in Fusion MOTA-2A (Powell/Doran 1988). This eliminates the need to process Fusion MOTA-2A through the IEM cell prior to insertion for FFTF Cycle 11A. The LMR MOTA design and safety analysis (Greenslade 1984) is the basis for much of this design and safety analysis report. This design description and safety analysis for the Fusion MOTA-2A is presented per the outline given in Chapter IV of the FTR User`s Guide (Taylor 1978). 35 refs., 17 figs., 9 tabs.

  15. Transgenic plants expressing ω-ACTX-Hv1a and snowdrop lectin (GNA) fusion protein show enhanced resistance to aphids.

    PubMed

    Nakasu, Erich Y T; Edwards, Martin G; Fitches, Elaine; Gatehouse, John A; Gatehouse, Angharad M R

    2014-01-01

    Recombinant fusion proteins containing arthropod toxins have been developed as a new class of biopesticides. The recombinant fusion protein Hv1a/GNA, containing the spider venom toxin ω-ACTX-Hv1a linked to snowdrop lectin (GNA) was shown to reduce survival of the peach-potato aphid Myzus persicae when delivered in artificial diet, with survival <10% after 8 days exposure to fusion protein at 1 mg/ml. Although the fusion protein was rapidly degraded by proteases in the insect, Hv1a/GNA oral toxicity to M. persicae was significantly greater than GNA alone. A construct encoding the fusion protein, including the GNA leader sequence, under control of the constitutive CaMV 35S promoter was transformed into Arabidopsis; the resulting plants contained intact fusion protein in leaf tissues at an estimated level of 25.6 ± 4.1 ng/mg FW. Transgenic Arabidopsis expressing Hv1a/GNA induced up to 40% mortality of M. persicae after 7 days exposure in detached leaf bioassays, demonstrating that transgenic plants can deliver fusion proteins to aphids. Grain aphids (Sitobion avenae) were more susceptible than M. persicae to the Hv1a/GNA fusion protein in artificial diet bioassays (LC50 = 0.73 mg/ml after 2 days against LC50 = 1.81 mg/ml for M. persicae), as they were not able to hydrolyze the fusion protein as readily as M. persicae. Expression of this fusion protein in suitable host plants for the grain aphid is likely to confer higher levels of resistance than that shown with the M. persicae/Arabidopsis model system.

  16. A rapid and efficient newly established method to detect COL1A1-PDGFB gene fusion in dermatofibrosarcoma protuberans

    SciTech Connect

    Yokoyama, Yoko; Shimizu, Akira; Okada, Etsuko; Ishikawa, Osamu; Motegi, Sei-ichiro

    2012-08-24

    Highlights: Black-Right-Pointing-Pointer We developed new method to rapidly identify COL1A1-PDGFB fusion in DFSP. Black-Right-Pointing-Pointer New PCR method using a single primer pair detected COL1A1-PDGFB fusion in DFSP. Black-Right-Pointing-Pointer This is the first report of DFSP with a novel COL1A1 breakpoint in exon 5. -- Abstract: The detection of fusion transcripts of the collagen type 1{alpha}1 (COL1A1) and platelet-derived growth factor-BB (PDGFB) genes by genetic analysis has recognized as a reliable and valuable molecular tool for the diagnosis of dermatofibrosarcoma protuberans (DFSP). To detect the COL1A1-PDGFB fusion, almost previous reports performed reverse transcription polymerase chain reaction (RT-PCR) using multiplex forward primers from COL1A1. However, it has possible technical difficulties with respect to the handling of multiple primers and reagents in the procedure. The objective of this study is to establish a rapid, easy, and efficient one-step method of PCR using only a single primer pair to detect the fusion transcripts of the COL1A1 and PDGFB in DFSP. To validate new method, we compared the results of RT-PCR in five patients of DFSP between the previous method using multiplex primers and our established one-step RT-PCR using a single primer pair. In all cases of DFSP, the COL1A1-PDGFB fusion was detected by both previous method and newly established one-step PCR. Importantly, we detected a novel COL1A1 breakpoint in exon 5. The newly developed method is valuable to rapidly identify COL1A1-PDGFB fusion transcripts in DFSP.

  17. IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein

    SciTech Connect

    Kwasnicka-Crawford, Dorota A. . E-mail: dakc@yorku.ca; Carson, Andrew R.; Scherer, Stephen W.

    2006-12-01

    The existence of transcripts that span two adjacent, independent genes is considered rare in the human genome. This study characterizes a novel human fusion gene named IQCJ-SCHIP1. IQCJ-SCHIP1 is the longest isoform of a complex transcriptional unit that bridges two separate genes that encode distinct proteins, IQCJ, a novel IQ motif containing protein and SCHIP1, a schwannomin interacting protein that has been previously shown to interact with the Neurofibromatosis type 2 (NF2) protein. IQCJ-SCHIP1 is located on the chromosome 3q25 and comprises a 1692-bp transcript encompassing 11 exons spanning 828 kb of the genomic DNA. We show that IQCJ-SCHIP1 mRNA is highly expressed in the brain. Protein encoded by the IQCJ-SCHIP1 gene was localized to cytoplasm and actin-rich regions and in differentiated PC12 cells was also seen in neurite extensions.

  18. Fusion

    NASA Astrophysics Data System (ADS)

    Herman, Robin

    1990-10-01

    The book abounds with fascinating anecdotes about fusion's rocky path: the spurious claim by Argentine dictator Juan Peron in 1951 that his country had built a working fusion reactor, the rush by the United States to drop secrecy and publicize its fusion work as a propaganda offensive after the Russian success with Sputnik; the fortune Penthouse magazine publisher Bob Guccione sank into an unconventional fusion device, the skepticism that met an assertion by two University of Utah chemists in 1989 that they had created "cold fusion" in a bottle. Aimed at a general audience, the book describes the scientific basis of controlled fusion--the fusing of atomic nuclei, under conditions hotter than the sun, to release energy. Using personal recollections of scientists involved, it traces the history of this little-known international race that began during the Cold War in secret laboratories in the United States, Great Britain and the Soviet Union, and evolved into an astonishingly open collaboration between East and West.

  19. Modification of a Hydrophobic Layer by a Point Mutation in Syntaxin 1A Regulates the Rate of Synaptic Vesicle Fusion

    PubMed Central

    Lagow, Robert D; Bao, Hong; Cohen, Evan N; Daniels, Richard W; Zuzek, Aleksej; Williams, Wade H; Macleod, Gregory T; Sutton, R. Bryan; Zhang, Bing

    2007-01-01

    Both constitutive secretion and Ca2+-regulated exocytosis require the assembly of the soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) complexes. At present, little is known about how the SNARE complexes mediating these two distinct pathways differ in structure. Using the Drosophila neuromuscular synapse as a model, we show that a mutation modifying a hydrophobic layer in syntaxin 1A regulates the rate of vesicle fusion. Syntaxin 1A molecules share a highly conserved threonine in the C-terminal +7 layer near the transmembrane domain. Mutation of this threonine to isoleucine results in a structural change that more closely resembles those found in syntaxins ascribed to the constitutive secretory pathway. Flies carrying the I254 mutant protein have increased levels of SNARE complexes and dramatically enhanced rate of both constitutive and evoked vesicle fusion. In contrast, overexpression of the T254 wild-type protein in neurons reduces vesicle fusion only in the I254 mutant background. These results are consistent with molecular dynamics simulations of the SNARE core complex, suggesting that T254 serves as an internal brake to dampen SNARE zippering and impede vesicle fusion, whereas I254 favors fusion by enhancing intermolecular interaction within the SNARE core complex. PMID:17341138

  20. Phase 1-A development kinematic Sterling/Rankine commercial gas-fired heat pump research program

    NASA Astrophysics Data System (ADS)

    Johansson, L.; Agno, J. G.; Houtman, W. H.

    1984-07-01

    Heat pumps driven by electric motors are successfully sold as energy saving systems in the space conditioning marketplace. By utilizing an on-site natural gas fueled Stirling cycle engine to drive a refrigerating compressor, energy consumption of such a heat pump can be reduced in both heating and cooling modes of operation. The achievements reached in Phase 1-A indicate that the goal of developing a technically and economically feasible commercial heat pump, using the V-160 Stirling engine, is practical and can be accomplished within a reasonable period of time. This initial investigation also indicates that the potential heat pump system can be responsive to a large market segment as well as providing a technological base for expanding into other gas market segments.

  1. Developing a commercial production process for 500,000 targets per day: A key challenge for inertial fusion energy

    SciTech Connect

    Goodin, D.T.; Alexander, N.B.; Besenbruch, G.E.; Bozek, A.S.; Brown, L.C.; Flint, G.W.; Kilkenny, J.D.; McQuillan, B.W.; Nikroo, A.; Paguio, R.R.; Petzoldt, R.W.; Schroen, D.G.; Sheliak, J.D.; Vermillion, B.A.; Carlson, L.C.; Goodman, P.; Maksaereekul, W.; Raffray, R.; Spalding, J.; Tillack, M.S.

    2006-05-15

    As is true for current-day commercial power plants, a reliable and economic fuel supply is essential for the viability of future Inertial Fusion Energy (IFE) [Energy From Inertial Fusion, edited by W. J. Hogan (International Atomic Energy Agency, Vienna, 1995)] power plants. While IFE power plants will utilize deuterium-tritium (DT) bred in-house as the fusion fuel, the 'target' is the vehicle by which the fuel is delivered to the reaction chamber. Thus the cost of the target becomes a critical issue in regard to fuel cost. Typically six targets per second, or about 500 000/day are required for a nominal 1000 MW(e) power plant. The electricity value within a typical target is about $3, allocating 10% for fuel cost gives only 30 cents per target as-delivered to the chamber center. Complicating this economic goal, the target supply has many significant technical challenge - fabricating the precision fuel-containing capsule, filling it with DT, cooling it to cryogenic temperatures, layering the DT into a uniform layer, characterizing the finished product, accelerating it to high velocity for injection into the chamber, and tracking the target to steer the driver beams to meet it with micron-precision at the chamber center.

  2. HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth.

    PubMed

    Blondelle, Jordan; Ohno, Yusuke; Gache, Vincent; Guyot, Stéphane; Storck, Sébastien; Blanchard-Gutton, Nicolas; Barthélémy, Inès; Walmsley, Gemma; Rahier, Anaëlle; Gadin, Stéphanie; Maurer, Marie; Guillaud, Laurent; Prola, Alexandre; Ferry, Arnaud; Aubin-Houzelstein, Geneviève; Demarquoy, Jean; Relaix, Frédéric; Piercy, Richard J; Blot, Stéphane; Kihara, Akio; Tiret, Laurent; Pilot-Storck, Fanny

    2015-10-01

    The reduced diameter of skeletal myofibres is a hallmark of several congenital myopathies, yet the underlying cellular and molecular mechanisms remain elusive. In this study, we investigate the role of HACD1/PTPLA, which is involved in the elongation of the very long chain fatty acids, in muscle fibre formation. In humans and dogs, HACD1 deficiency leads to a congenital myopathy with fibre size disproportion associated with a generalized muscle weakness. Through analysis of HACD1-deficient Labradors, Hacd1-knockout mice, and Hacd1-deficient myoblasts, we provide evidence that HACD1 promotes myoblast fusion during muscle development and regeneration. We further demonstrate that in normal differentiating myoblasts, expression of the catalytically active HACD1 isoform, which is encoded by a muscle-enriched splice variant, yields decreased lysophosphatidylcholine content, a potent inhibitor of myoblast fusion, and increased concentrations of ≥ C18 and monounsaturated fatty acids of phospholipids. These lipid modifications correlate with a reduction in plasma membrane rigidity. In conclusion, we propose that fusion impairment constitutes a novel, non-exclusive pathological mechanism operating in congenital myopathies and reveal that HACD1 is a key regulator of a lipid-dependent muscle fibre growth mechanism. PMID:26160855

  3. Fusion of Synthetic and Enhanced Vision for All-Weather Commercial Aviation Operations

    NASA Technical Reports Server (NTRS)

    Bailey, Randall E.; Kramer, Lynda J.; Prinzel, Lawrence, III

    2007-01-01

    NASA is developing revolutionary crew-vehicle interface technologies that strive to proactively overcome aircraft safety barriers that would otherwise constrain the full realization of the next-generation air transportation system. A piloted simulation experiment was conducted to evaluate the complementary use of Synthetic and Enhanced Vision technologies. Specific focus was placed on new techniques for integration and/or fusion of Enhanced and Synthetic Vision and its impact within a two-crew flight deck during low visibility approach and landing operations. Overall, the experimental data showed that significant improvements in situation awareness, without concomitant increases in workload and display clutter, could be provided by the integration and/or fusion of synthetic and enhanced vision technologies for the pilot-flying and the pilot-not-flying. During non-normal operations, the ability of the crew to handle substantial navigational errors and runway incursions were not adversely impacted by the display concepts although the addition of Enhanced Vision did not, unto itself, provide an improvement in runway incursion detection.

  4. Optimising expression of the recombinant fusion protein biopesticide ω-hexatoxin-Hv1a/GNA in Pichia pastoris: sequence modifications and a simple method for the generation of multi-copy strains.

    PubMed

    Pyati, Prashant; Fitches, Elaine; Gatehouse, John A

    2014-08-01

    Production of recombinant protein bio-insecticides on a commercial scale can only be cost effective if host strains with very high expression levels are available. A recombinant fusion protein containing an arthropod toxin, ω-hexatoxin-Hv1a, (from funnel web spider Hadronyche versuta) linked to snowdrop lectin (Galanthus nivalis agglutinin; GNA) is an effective oral insecticide and candidate biopesticide. However, the fusion protein was vulnerable to proteolysis during production in the yeast Pichia pastoris. To prevent proteolysis, the Hv1a/GNA fusion expression construct was modified by site-directed mutagenesis to remove a potential Kex2 cleavage site at the C-terminus of the Hv1a peptide. To obtain a high expressing clone of P. pastoris to produce recombinant Hv1a/GNA, a straightforward method was used to produce multi-copy expression plasmids, which does not require multiple integrations to give clones of P. pastoris containing high copy numbers of the introduced gene. Removal of the Kex2 site resulted in increased levels of intact fusion protein expressed in wild-type P. pastoris strains, improving levels of intact recombinant protein recoverable. Incorporation of a C-terminal (His)6 tag enabled single step purification of the fusion protein. These modifications did not affect the insecticidal activity of the recombinant toxin towards lepidopteran larvae. Introduction of multiple expression cassettes increased the amount of secreted recombinant fusion protein in a laboratory scale fermentation by almost tenfold on a per litre of culture basis. Simple modifications in the expression construct can be advantageous for the generation of high expressing P. pastoris strains for production of a recombinant protein, without altering its functional properties.

  5. Optimising expression of the recombinant fusion protein biopesticide ω-hexatoxin-Hv1a/GNA in Pichia pastoris: sequence modifications and a simple method for the generation of multi-copy strains.

    PubMed

    Pyati, Prashant; Fitches, Elaine; Gatehouse, John A

    2014-08-01

    Production of recombinant protein bio-insecticides on a commercial scale can only be cost effective if host strains with very high expression levels are available. A recombinant fusion protein containing an arthropod toxin, ω-hexatoxin-Hv1a, (from funnel web spider Hadronyche versuta) linked to snowdrop lectin (Galanthus nivalis agglutinin; GNA) is an effective oral insecticide and candidate biopesticide. However, the fusion protein was vulnerable to proteolysis during production in the yeast Pichia pastoris. To prevent proteolysis, the Hv1a/GNA fusion expression construct was modified by site-directed mutagenesis to remove a potential Kex2 cleavage site at the C-terminus of the Hv1a peptide. To obtain a high expressing clone of P. pastoris to produce recombinant Hv1a/GNA, a straightforward method was used to produce multi-copy expression plasmids, which does not require multiple integrations to give clones of P. pastoris containing high copy numbers of the introduced gene. Removal of the Kex2 site resulted in increased levels of intact fusion protein expressed in wild-type P. pastoris strains, improving levels of intact recombinant protein recoverable. Incorporation of a C-terminal (His)6 tag enabled single step purification of the fusion protein. These modifications did not affect the insecticidal activity of the recombinant toxin towards lepidopteran larvae. Introduction of multiple expression cassettes increased the amount of secreted recombinant fusion protein in a laboratory scale fermentation by almost tenfold on a per litre of culture basis. Simple modifications in the expression construct can be advantageous for the generation of high expressing P. pastoris strains for production of a recombinant protein, without altering its functional properties. PMID:24898110

  6. A comparison of commercially available demineralized bone matrices with and without human mesenchymal stem cells in a rodent spinal fusion model.

    PubMed

    Hayashi, Tetsuo; Lord, Elizabeth L; Suzuki, Akinobu; Takahashi, Shinji; Scott, Trevor P; Phan, Kevin; Tian, Haijun; Daubs, Michael D; Shiba, Keiichiro; Wang, Jeffrey C

    2016-07-01

    OBJECTIVE The efficacy of some demineralized bone matrix (DBM) substances has been demonstrated in the spinal fusion of rats; however, no previous comparative study has reported the efficacy of DBM with human mesenchymal stem cells (hMSCs). There is an added cost to the products with stem cells, which should be justified by improved osteogenic potential. The purpose of this study is to prospectively compare the fusion rates of 3 different commercially available DBM substances, both with and without hMSCs. METHODS Posterolateral fusion was performed in 32 mature athymic nude rats. Three groups of 8 rats were implanted with 1 of 3 DBMs: Trinity Evolution (DBM with stem cells), Grafton (DBM without stem cells), or DBX (DBM without stem cells). A fourth group with no implanted material was used as a control group. Radiographs were obtained at 2, 4, and 8 weeks. The rats were euthanized at 8 weeks. Overall fusion was determined by manual palpation and micro-CT. RESULTS The fusion rates at 8 weeks on the radiographs for Trinity Evolution, Grafton, and DBX were 8 of 8 rats, 3 of 8 rats, and 5 of 8 rats, respectively. A significant difference was found between Trinity Evolution and Grafton (p = 0.01). The overall fusion rates as determined by micro-CT and manual palpation for Trinity Evolution, Grafton, and DBX were 4 of 8 rats, 3 of 8 rats, and 3 of 8 rats, respectively. The Trinity Evolution substance had the highest overall fusion rate, however no significant difference was found between groups. CONCLUSIONS The efficacies of these DBM substances are demonstrated; however, the advantage of DBM with hMSCs could not be found in terms of posterolateral fusion. When evaluating spinal fusion using DBM substances, CT analysis is necessary in order to not overestimate fusion.

  7. The EFF-1A Cytoplasmic Domain Influences Hypodermal Cell Fusions in C. elegans But Is Not Dependent on 14-3-3 Proteins

    PubMed Central

    Shinn-Thomas, Jessica H.; del Campo, Jacob J.; Wang, Jianjun; Mohler, William A.

    2016-01-01

    Background Regulatory and biophysical mechanisms of cell-cell fusion are largely unknown despite the fundamental requirement for fused cells in eukaryotic development. Only two cellular fusogens that are not of clear recent viral origin have been identified to date, both in nematodes. One of these, EFF-1, is necessary for most cell fusions in Caenorhabditis elegans. Unregulated EFF-1 expression causes lethality due to ectopic fusion between cells not developmentally programmed to fuse, highlighting the necessity of tight fusogen regulation for proper development. Identifying factors that regulate EFF-1 and its paralog AFF-1 could lead to discovery of molecular mechanisms that control cell fusion upstream of the action of a membrane fusogen. Bioinformatic analysis of the EFF-1A isoform’s predicted cytoplasmic domain (endodomain) previously revealed two motifs that have high probabilities of interacting with 14-3-3 proteins when phosphorylated. Mutation of predicted phosphorylation sites within these motifs caused measurable loss of eff-1 gene function in cell fusion in vivo. Moreover, a human 14-3-3 isoform bound to EFF-1::GFP in vitro. We hypothesized that the two 14-3-3 proteins in C. elegans, PAR-5 and FTT-2, may regulate either localization or fusion-inducing activity of EFF-1. Methodology/Principal Findings Timing of fusion events was slightly but significantly delayed in animals unable to produce full-length EFF-1A. Yet, mutagenesis and live imaging showed that phosphoserines in putative 14-3-3 binding sites are not essential for EFF-1::GFP accumulation at the membrane contact between fusion partner cells. Moreover, although the EFF-1A endodomain was required for normal rates of eff-1-dependent epidermal cell fusions, reduced levels of FTT-2 and PAR-5 did not visibly affect the function of wild-type EFF-1 in the hypodermis. Conclusions/Significance Deletion of the EFF-1A endodomain noticeably affects the timing of hypodermal cell fusions in vivo. However

  8. Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli.

    PubMed Central

    Spindler, K R; Rosser, D S; Berk, A J

    1984-01-01

    Plasmid vectors were constructed which expressed three adenovirus tumor antigens fused to a portion of the trpE protein of Escherichia coli. Insertion of adenovirus type 2 DNA from early region 1A (E1A) into such a plasmid led to a fusion protein which contained the C-terminal 266 amino acids of the 289-amino acid protein encoded by the viral 13S mRNA. Similarly, insertion of adenovirus type 5 DNA corresponding to the E1B 55- and 21-kilodalton proteins led to production of fusion proteins containing amino acid sequences from these proteins. After induction with indoleacrylic acid, fusion proteins accumulated stably in the E. coli cells. By using a simple extraction of insoluble protein, 1 to 10 mg of fusion protein per liter of culture was obtained. The fusion proteins were purified on preparative polyacrylamide gels and used to immunize rabbits. Specific antisera for the E1A 289- and closely related 243-amino acid proteins and the E1B 55- and 21-kilodalton proteins were obtained. These sera were used to immunoprecipitate the tumor antigens in cells infected with wild-type and various mutants of adenovirus or to analyze them by an immunoblotting procedure. Mutant E1A proteins in which the C-terminal 70 amino acids are deleted were phosphorylated to much lower extents than the wild-type E1A proteins. This indicates that the deleted region is important for the process of phosphorylation. The E1A proteins were extracted, sedimented in glycerol gradients, analyzed by immunoprecipitation, and found to sediment primarily as monomers. Images PMID:6361277

  9. Quantitative determination and validation of avermectin B1a in commercial products using quantitative nuclear magnetic resonance spectroscopy.

    PubMed

    Hou, Zhuoni; Liang, Xianrui; Du, Liping; Su, Feng; Su, Weike

    2014-09-01

    Nuclear magnetic resonance is defined as a quantitative spectroscopic tool that enables a precise determination of the number of substances in liquids as well as in solids. There is few report demonstrating the application of NMR in the quantification of avermectin B1a (AVB1a ); here, a proton nuclear magnetic resonance spectroscopy ((1) H NMR) using benzene [1-methoxy-4-(2-nitroethyl) (PMN)] as an internal standard and deuterochloroform as an NMR solvent was tested for the quantitative determination of AVB1a . The integrated signal of AVB1a at 5.56 ppm and the signal of PMN at 8.14 ppm in the (1) H NMR spectrum were used for quantification purposes. Parameters of specificity, linearity, accuracy, precision, intermediate precision, range, limit of detection (LOD), limit of quantification (LOQ), stability and robustness were validated. The established method was accurate and precise with good recovery (98.86%) and relative standard deviation (RSD) of assay (0.34%) within the linearity of the calibration curve ranging from 5.08 to 13.58 mg/ml (R(2)  = 0.9999). The LOD and LOQ were 0.009 and 0.029 mg/ml, which indicated the excellent sensitivity of the method. The stability of the method was testified by a calculated RSD of 0.11%. The robustness was testified by modification of four different parameters, and the differences among each parameter were all less than 0.1%. Comparing with the assay described by the manufacturer of avermectin tablets, there was no significant difference between the assay obtained by HPLC and quantitative NMR (qNMR), which indicated qNMR was a simple and efficient method for the determination of AVB1a in commercial formulation products. PMID:24943110

  10. Adenovirus type 12 E1A protein expressed in Escherichia coli is functional upon transfer by microinjection or protoplast fusion into mammalian cells.

    PubMed Central

    Krippl, B; Andrisani, O; Jones, N; Westphal, H; Rosenberg, M; Ferguson, B

    1986-01-01

    We efficiently expressed, in Escherichia coli, and purified the protein product encoded by the human adenovirus type 12 (Ad12) 13S mRNA. The functional properties of the E1A protein were analyzed by introducing the protein by microinjection or protoplast fusion into living mammalian cells. We showed that the E. coli-expressed E1A protein induces gene expression of the adenovirus type 5 (Ad5) E1A deletion mutant Ad5dl312. The purified E1A protein rapidly and quantitatively localized to the cell nucleus after microinjection into the cytoplasm. In addition, we raised high-titered monospecific antibodies to the purified Ad12 E1A protein. Using deleted forms of an adenovirus type 2 and Ad5 hybrid (Ad2/5) E1A protein, we showed that all of the epitopes conserved between Ad2/5 E1A and Ad12 E1A protein that are recognized by the Ad12 E1A-specific antiserum map to within the first exon-encoded amino-terminal half of the protein. Images PMID:2942704

  11. Neutronic design studies of a conceptual DCLL fusion reactor for a DEMO and a commercial power plant

    NASA Astrophysics Data System (ADS)

    Palermo, I.; Veredas, G.; Gómez-Ros, J. M.; Sanz, J.; Ibarra, A.

    2016-01-01

    Neutronic analyses or, more widely, nuclear analyses have been performed for the development of a dual-coolant He/LiPb (DCLL) conceptual design reactor. A detailed three-dimensional (3D) model has been examined and optimized. The design is based on the plasma parameters and functional materials of the power plant conceptual studies (PPCS) model C. The initial radial-build for the detailed model has been determined according to the dimensions established in a previous work on an equivalent simplified homogenized reactor model. For optimization purposes, the initial specifications established over the simplified model have been refined on the detailed 3D design, modifying material and dimension of breeding blanket, shield and vacuum vessel in order to fulfil the priority requirements of a fusion reactor in terms of the fundamental neutronic responses. Tritium breeding ratio, energy multiplication factor, radiation limits in the TF coils, helium production and displacements per atom (dpa) have been calculated in order to demonstrate the functionality and viability of the reactor design in guaranteeing tritium self-sufficiency, power efficiency, plasma confinement, and re-weldability and structural integrity of the components. The paper describes the neutronic design improvements of the DCLL reactor, obtaining results for both DEMO and power plant operational scenarios.

  12. FRAG1, a gene that potently activates fibroblast growth factor receptor by C-terminal fusion through chromosomal rearrangement.

    PubMed Central

    Lorenzi, M V; Horii, Y; Yamanaka, R; Sakaguchi, K; Miki, T

    1996-01-01

    A constitutively active form of fibroblast growth factor 2 (FGFR2) was identified in rat osteosarcoma (ROS) cells by an expression cloning strategy. Unlike other tyrosine kinase receptors activated by N-terminal truncation in tumors, this receptor, FGFR2-ROS, contains an altered C terminus generated from chromosomal rearrangement with a novel gene, designated FGFR activating gene 1 (FRAG1). While the removal of the C terminus slightly activates FGFR2, the presence of the FRAG1 sequence drastically stimulates the transforming activity and autophosphorylation of the receptor. FGFR2-ROS is expressed as a unusually large protein and is highly phosphorylated in NIH 3T3 transfectants. FRAG1 is ubiquitously expressed and encodes a predicted protein of 28 kDa lacking significant structural similarity to known proteins. Epitope-tagged FRAG1 protein showed a perinuclear localization by immunofluorescence staining. The highly activated state of FGFR2-ROS appears to be attributed to constitutive dimer formation and higher phosphorylation level as well as possibly altered subcellular localization. These results indicate a unique mechanism of receptor activation by a C terminus alteration through a chromosomal fusion with FRAG1. Images Fig. 1 Fig. 2 Fig. 3 Fig. 5 Fig. 6 PMID:8799135

  13. Homology with vesicle fusion mediator syntaxin-1a predicts determinants ofepimorphin/syntaxin-2 function in mammary epithelial morphogenesis

    SciTech Connect

    Chen, Connie S.; Nelson, Celeste M.; Khauv, Davitte; Bennett, Simone; Radisky, Evette S.; Hirai, Yohei; Bissell, Mina J.; Radisky, Derek C.

    2009-06-03

    We have shown that branching morphogenesis of mammary ductal structures requires the action of the morphogen epimorphin/syntaxin-2. Epimorphin, originally identified as an extracellular molecule, is identical to syntaxin-2, an intracellular molecule that is a member of the extensively investigated syntaxin family of proteins that mediate vesicle trafficking. We show here that although epimorphin/syntaxin-2 is highly homologous to syntaxin-1a, only epimorphin/syntaxin-2 can stimulate mammary branching morphogenesis. We construct a homology model of epimorphin/syntaxin-2 based on the published structure of syntaxin-1a, and we use this model to identify the structural motif responsible for the morphogenic activity. We identify four residues located within the cleft between helices B and C that differ between syntaxin-1a and epimorphin/syntaxin-2; through site-directed mutagenesis of these four amino acids, we confer the properties of epimorphin for cell adhesion, gene activation, and branching morphogenesis onto the inactive syntaxin-1a template. These results provide a dramatic demonstration of the use of structural information about one molecule to define a functional motif of a second molecule that is related at the sequence level but highly divergent functionally.

  14. Spinal fusion

    MedlinePlus

    ... Anterior spinal fusion; Spine surgery - spinal fusion; Low back pain - fusion; Herniated disk - fusion ... If you had chronic back pain before surgery, you will likely still have some pain afterward. Spinal fusion is unlikely to take away all your pain ...

  15. Fusion facility siting considerations

    NASA Astrophysics Data System (ADS)

    Bussell, G. T.

    1985-02-01

    Inherent in the fusion program's transition from hydrogen devices to commercial power machines is a general increase in the size and scope of succeeding projects. This growth will lead to increased emphasis on safety, environmental impact, and the external effects of fusion in general, and of each new device in particular. An important consideration in this regard is site selection. Major siting issues that may affect the economics, safety, and environmental impact of fusion are examined.

  16. TPD52L1-ROS1, a new ROS1 fusion variant in lung adenosquamous cell carcinoma identified by comprehensive genomic profiling.

    PubMed

    Zhu, Viola Weijia; Upadhyay, Daya; Schrock, Alexa B; Gowen, Kyle; Ali, Siraj M; Ou, Sai-Hong Ignatius

    2016-07-01

    Crizotinib was approved for the treatment of ROS1-rearranged non-small cell lung cancer (NSCLC) patients in the US on 11 March, 2016. Interestingly no one companion diagnostic test (CDx) has been approved simultaneously with this approval of crizotinib. Hence, an ideal and adequate CDx will have to be able to identify ROS1 fusions without the knowledge of the fusion partners to ROS1, and as to date there are 13 fusion partners reported for ROS1 in NSCLC. Here we report a novel TPD52L1-ROS1 fusion variant in NSCLC. This novel TPD52L1-ROS1 fusion variant is generated by the fusion of exons 1-3 of TPD52L1 on chromosome 6q22-23 to the exons 33-43 of ROS1 on chromosome 6q22, likely from an intra-chromosomal deletion and subsequent fusion event similar to the generation of EML4-ALK. The predicted TPD52L1-ROS1 protein product contains 655 amino acids comprising of the N-terminal amino acids 1-95 of TPD52L1 and C-terminal amino acids of 1789-2348 of ROS1. In summary, TPD52L1-ROS1 is a novel ROS1 fusion variant in NSCLC identified by comprehensive genomic profiling and should be included in any ROS1 detecting assays that depend on identifying the corresponding fusion partners, such as reverse transcriptase-polymerase chain reaction (RT-PCR). PMID:27237027

  17. Materials research for fusion

    NASA Astrophysics Data System (ADS)

    Knaster, J.; Moeslang, A.; Muroga, T.

    2016-05-01

    Fusion materials research started in the early 1970s following the observation of the degradation of irradiated materials used in the first commercial fission reactors. The technological challenges of fusion energy are intimately linked with the availability of suitable materials capable of reliably withstanding the extremely severe operational conditions of fusion reactors. Although fission and fusion materials exhibit common features, fusion materials research is broader. The harder mono-energetic spectrum associated with the deuterium-tritium fusion neutrons (14.1 MeV compared to <2 MeV on average for fission neutrons) releases significant amounts of hydrogen and helium as transmutation products that might lead to a (at present undetermined) degradation of structural materials after a few years of operation. Overcoming the historical lack of a fusion-relevant neutron source for materials testing is an essential pending step in fusion roadmaps. Structural materials development, together with research on functional materials capable of sustaining unprecedented power densities during plasma operation in a fusion reactor, have been the subject of decades of worldwide research efforts underpinning the present maturity of the fusion materials research programme.

  18. Big fusion, little fusion

    NASA Astrophysics Data System (ADS)

    Chen, Frank; ddtuttle

    2016-08-01

    In reply to correspondence from George Scott and Adam Costley about the Physics World focus issue on nuclear energy, and to news of construction delays at ITER, the fusion reactor being built in France.

  19. Multisensor data fusion algorithm development

    SciTech Connect

    Yocky, D.A.; Chadwick, M.D.; Goudy, S.P.; Johnson, D.K.

    1995-12-01

    This report presents a two-year LDRD research effort into multisensor data fusion. We approached the problem by addressing the available types of data, preprocessing that data, and developing fusion algorithms using that data. The report reflects these three distinct areas. First, the possible data sets for fusion are identified. Second, automated registration techniques for imagery data are analyzed. Third, two fusion techniques are presented. The first fusion algorithm is based on the two-dimensional discrete wavelet transform. Using test images, the wavelet algorithm is compared against intensity modulation and intensity-hue-saturation image fusion algorithms that are available in commercial software. The wavelet approach outperforms the other two fusion techniques by preserving spectral/spatial information more precisely. The wavelet fusion algorithm was also applied to Landsat Thematic Mapper and SPOT panchromatic imagery data. The second algorithm is based on a linear-regression technique. We analyzed the technique using the same Landsat and SPOT data.

  20. Accelerators for heavy ion fusion

    SciTech Connect

    Bangerter, R.O.

    1985-10-01

    Large fusion devices will almost certainly produce net energy. However, a successful commercial fusion energy system must also satisfy important engineering and economic constraints. Inertial confinement fusion power plants driven by multi-stage, heavy-ion accelerators appear capable of meeting these constraints. The reasons behind this promising outlook for heavy-ion fusion are given in this report. This report is based on the transcript of a talk presented at the Symposium on Lasers and Particle Beams for Fusion and Strategic Defense at the University of Rochester on April 17-19, 1985.

  1. The path to fusion power.

    PubMed

    Llewellyn Smith, Chris; Ward, David

    2007-04-15

    Fusion is potentially an environmentally responsible and intrinsically safe source of essentially limitless power. It should be possible to build viable fusion power stations, and it looks as if the cost of fusion power will be reasonable. But time is needed to further develop the technology and to test in power station conditions the materials that would be used in their construction. Assuming no major adverse surprises, an orderly fusion development programme could lead to a prototype fusion power station putting electricity into the grid within 30 years, with commercial fusion power following some 10 or more years later. In the second half of the century, fusion could therefore be an important part of the portfolio of measures that are needed to cope with rising demand for energy in an environmentally responsible manner. In this paper, we describe the basics of fusion, its potential attractions, the status of fusion R&D, the remaining challenges and how they will be tackled at the International Tokamak Experimental Reactor and the proposed International Fusion Materials Irradiation Facility, and the timetable for the subsequent commercialization of fusion power. PMID:17272246

  2. Lithium question for nuclear fusion

    SciTech Connect

    Shieh, P.S.S.

    1981-01-01

    An attempt is made to estimate the lithium reserve (the economically recoverable lithium) for the tritium breeding in D-T fusion reactors and other uses. Similar development patterns for fusion energy and fission energy are assumed to estimate the future lithium requirements. These requirements are grouped into three categories; the commercial uses, the lithium batteries for electric cars, and the fusion reactor uses. 5 refs.

  3. The quest for fusion power

    NASA Astrophysics Data System (ADS)

    Cowley, Steven C.

    2016-05-01

    Fusion power is one of a very few sustainable options to replace fossil fuels as the world's primary energy source. Although the conditions for fusion have been reached, much remains to be done to turn scientific success into commercial electrical power.

  4. FgMon1, a guanine nucleotide exchange factor of FgRab7, is important for vacuole fusion, autophagy and plant infection in Fusarium graminearum.

    PubMed

    Li, Ying; Li, Bing; Liu, Luping; Chen, Huaigu; Zhang, Haifeng; Zheng, Xiaobo; Zhang, Zhengguang

    2015-01-01

    The Ccz1-Mon1 protein complex, the guanine nucleotide exchange factor (GEF) of the late endosomal Rab7 homolog Ypt7, is required for the late step of multiple vacuole delivery pathways, such as cytoplasm-to-vacuole targeting (Cvt) pathway and autophagy processes. Here, we identified and characterized the yeast Mon1 homolog in Fusarium graminearum, named FgMon1. FgMON1 encodes a trafficking protein and is well conserved in filamentous fungi. Targeted gene deletion showed that the ∆Fgmon1 mutant was defective in vegetative growth, asexual/sexual development, conidial germination and morphology, plant infection and deoxynivalenol production. Cytological examination revealed that the ∆Fgmon1 mutant was also defective in vacuole fusion and autophagy, and delayed in endocytosis. Yeast two hybrid and in vitro GST-pull down assays approved that FgMon1 physically interacts with a Rab GTPase FgRab7 which is also important for the development, infection, membrane fusion and autophagy in F. graminearum. FgMon1 likely acts as a GEF of FgRab7 and constitutively activated FgRab7 was able to rescue the defects of the ∆Fgmon1 mutant. In summary, our study provides evidences that FgMon1 and FgRab7 are critical components that modulate vesicle trafficking, endocytosis and autophagy, and thereby affect the development, plant infection and DON production of F. graminearum.

  5. FgMon1, a guanine nucleotide exchange factor of FgRab7, is important for vacuole fusion, autophagy and plant infection in Fusarium graminearum

    PubMed Central

    Li, Ying; Li, Bing; Liu, Luping; Chen, Huaigu; Zhang, Haifeng; Zheng, Xiaobo; Zhang, Zhengguang

    2015-01-01

    The Ccz1-Mon1 protein complex, the guanine nucleotide exchange factor (GEF) of the late endosomal Rab7 homolog Ypt7, is required for the late step of multiple vacuole delivery pathways, such as cytoplasm-to-vacuole targeting (Cvt) pathway and autophagy processes. Here, we identified and characterized the yeast Mon1 homolog in Fusarium graminearum, named FgMon1. FgMON1 encodes a trafficking protein and is well conserved in filamentous fungi. Targeted gene deletion showed that the ∆Fgmon1 mutant was defective in vegetative growth, asexual/sexual development, conidial germination and morphology, plant infection and deoxynivalenol production. Cytological examination revealed that the ∆Fgmon1 mutant was also defective in vacuole fusion and autophagy, and delayed in endocytosis. Yeast two hybrid and in vitro GST-pull down assays approved that FgMon1 physically interacts with a Rab GTPase FgRab7 which is also important for the development, infection, membrane fusion and autophagy in F. graminearum. FgMon1 likely acts as a GEF of FgRab7 and constitutively activated FgRab7 was able to rescue the defects of the ∆Fgmon1 mutant. In summary, our study provides evidences that FgMon1 and FgRab7 are critical components that modulate vesicle trafficking, endocytosis and autophagy, and thereby affect the development, plant infection and DON production of F. graminearum. PMID:26657788

  6. A Plan for the Development of Fusion Energy. Final Report to Fusion Energy Sciences Advisory Committee, Fusion Development Path Panel

    SciTech Connect

    None, None

    2003-03-05

    This report presents a plan for the deployment of a fusion demonstration power plant within 35 years, leading to commercial application of fusion energy by mid-century. The plan is derived from the necessary features of a demonstration fusion power plant and from the time scale defined by President Bush. It identifies critical milestones, key decision points, needed major facilities and required budgets.

  7. Fusion-power demonstration

    NASA Astrophysics Data System (ADS)

    Henning, C. D.; Logan, B. G.; Carlson, G. A.; Neef, W. S.; Moir, R. W.; Campbell, R. B.; Botwin, R.; Clarkson, I. R.; Carpenter, T. J.

    1983-03-01

    As a satellite to the MARS (Mirror Advanced Reactor Study) a smaller, near-term device has been scoped, called the FPD (Fusion Power Demonstration). Envisioned as the next logical step toward a power reactor, it would advance the mirror fusion program beyond MFTF-B and provide an intermediate step toward commercial fusion power. Breakeven net electric power capability would be the goal such that no net utility power would be required to sustain the operation. A phased implementation is envisioned, with a deuterium checkout first to verify the plasma systems before significant neutron activation has occurred. Major tritium-related facilities would be installed with the second phase to produce sufficient fusion power to supply the recirculating power to maintain the neutral beams, ECRH, magnets and other auxiliary equipment.

  8. The Path to Magnetic Fusion Energy

    SciTech Connect

    Prager, Stewart

    2011-05-04

    When the possibility of fusion as an energy source for electricity generation was realized in the 1950s, understanding of the plasma state was primitive. The fusion goal has been paced by, and has stimulated, the development of plasma physics. Our understanding of complex, nonlinear processes in plasmas is now mature. We can routinely produce and manipulate 100 million degree plasmas with remarkable finesse, and we can identify a path to commercial fusion power. The international experiment, ITER, will create a burning (self-sustained) plasma and produce 500 MW of thermal fusion power. This talk will summarize the progress in fusion research to date, and the remaining steps to fusion power.

  9. Z-Pinch Fusion for Energy Applications

    SciTech Connect

    SPIELMAN,RICK B.

    2000-01-01

    Z pinches, the oldest fusion concept, have recently been revisited in light of significant advances in the fields of plasma physics and pulsed power engineering. The possibility exists for z-pinch fusion to play a role in commercial energy applications. We report on work to develop z-pinch fusion concepts, the result of an extensive literature search, and the output for a congressionally-mandated workshop on fusion energy held in Snowmass, Co July 11-23,1999.

  10. Nuclear Fusion

    NASA Astrophysics Data System (ADS)

    Veres, G.

    This chapter is devoted to the fundamental concepts of nuclear fusion. To be more precise, it is devoted to the theoretical basics of fusion reactions between light nuclei such as hydrogen, helium, boron, and lithium. The discussion is limited because our purpose is to focus on laboratory-scale fusion experiments that aim at gaining energy from the fusion process. After discussing the methods of calculating the fusion cross section, it will be shown that sustained fusion reactions with energy gain must happen in a thermal medium because, in beam-target experiments, the energy of the beam is randomized faster than the fusion rate. Following a brief introduction to the elements of plasma physics, the chapter is concluded with the introduction of the most prominent fusion reactions ongoing in the Sun.

  11. Object-oriented fusion of RADARSAT-2 polarimetric synthetic aperture radar and HJ-1A multispectral data for land-cover classification

    NASA Astrophysics Data System (ADS)

    Xiao, Yan; Jiang, Qigang; Wang, Bin; Li, Yuanhua; Liu, Shu; Cui, Can

    2016-04-01

    The contribution of the integration of optical and polarimetric synthetic aperture radar (PolSAR) data to accurate land-cover classification was investigated. For this purpose, an object-oriented classification methodology that consisted of polarimetric decomposition, hybrid feature selection, and a support vector machine (SVM) was proposed. A RADARSAT-2 Fine Quad-Pol image and an HJ-1A CCD2 multispectral image were used as data sources. First, polarimetric decomposition was implemented for the RADARSAT-2 image. Sixty-one polarimetric parameters were extracted using different polarimetric decomposition methods and then merged with the main diagonal elements (T11, T22, T33) of the coherency matrix to form a multichannel image with 64 layers. Second, the HJ-1A and the multichannel images were divided into numerous image objects by implementing multiresolution segmentation. Third, 1104 features were extracted from the HJ-1A and the multichannel images for each image object. Fourth, the hybrid feature selection method that combined the ReliefF filter approach and the genetic algorithm (GA) wrapper approach (ReliefF-GA) was used. Finally, land-cover classification was performed by an SVM classifier on the basis of the selected features. Five other classification methodologies were conducted for comparison to verify the contribution of optical and PolSAR data integration and to test the superiority of the proposed object-oriented classification methodology. Comparison results show that HJ-1A data, RADARSAT-2 data, polarimetric decomposition, ReliefF-GA, and SVM have a significant contribution by improving land-cover classification accuracy.

  12. Ceramics for fusion applications

    SciTech Connect

    Clinard, F.W. Jr.

    1986-01-01

    Ceramics are required for a variety of uses in both near-term fusion devices and in commercial powerplants. These materials must retain adequate structural and electrical properties under conditions of neutron, particle, and ionizing irradiation; thermal and applied stresses; and physical and chemical sputtering. Ceramics such as Al/sub 2/O/sub 3/, MgAl/sub 2/O/sub 4/, BeO, Si/sub 3/N/sub 4/ and SiC are currently under study for fusion applications, and results to date show widely-varying response to the fusion environment. Materials can be identified today which will meet initial operating requirements, but improvements in physical properties are needed to achieve satisfactory lifetimes for critical applications.

  13. Simulation of Fusion Plasmas

    ScienceCinema

    Holland, Chris [UC San Diego, San Diego, California, United States

    2016-07-12

    The upcoming ITER experiment (www.iter.org) represents the next major milestone in realizing the promise of using nuclear fusion as a commercial energy source, by moving into the “burning plasma” regime where the dominant heat source is the internal fusion reactions. As part of its support for the ITER mission, the US fusion community is actively developing validated predictive models of the behavior of magnetically confined plasmas. In this talk, I will describe how the plasma community is using the latest high performance computing facilities to develop and refine our models of the nonlinear, multiscale plasma dynamics, and how recent advances in experimental diagnostics are allowing us to directly test and validate these models at an unprecedented level.

  14. Fusion Implementation

    SciTech Connect

    J.A. Schmidt

    2002-02-20

    If a fusion DEMO reactor can be brought into operation during the first half of this century, fusion power production can have a significant impact on carbon dioxide production during the latter half of the century. An assessment of fusion implementation scenarios shows that the resource demands and waste production associated with these scenarios are manageable factors. If fusion is implemented during the latter half of this century it will be one element of a portfolio of (hopefully) carbon dioxide limiting sources of electrical power. It is time to assess the regional implications of fusion power implementation. An important attribute of fusion power is the wide range of possible regions of the country, or countries in the world, where power plants can be located. Unlike most renewable energy options, fusion energy will function within a local distribution system and not require costly, and difficult, long distance transmission systems. For example, the East Coast of the United States is a prime candidate for fusion power deployment by virtue of its distance from renewable energy sources. As fossil fuels become less and less available as an energy option, the transmission of energy across bodies of water will become very expensive. On a global scale, fusion power will be particularly attractive for regions separated from sources of renewable energy by oceans.

  15. Economic potential of inertial fusion

    SciTech Connect

    Nuckolls, J.H.

    1984-04-01

    Beyond the achievement of scientific feasibility, the key question for fusion energy is: does it have the economic potential to be significantly cheaper than fission and coal energy. If fusion has this high economic potential then there are compelling commercial and geopolitical incentives to accelerate the pace of the fusion program in the near term, and to install a global fusion energy system in the long term. Without this high economic potential, fusion's success depends on the failure of all alternatives, and there is no real incentive to accelerate the program. If my conjectures on the economic potential of inertial fusion are approximately correct, then inertial fusion energy's ultimate costs may be only half to two-thirds those of advanced fission and coal energy systems. Relative cost escalation is not assumed and could increase this advantage. Both magnetic and inertial approaches to fusion potentially have a two-fold economic advantage which derives from two fundamental properties: negligible fuel costs and high quality energy which makes possible more efficient generation of electricity. The wining approach to fusion may excel in three areas: electrical generating efficiency, minimum material costs, and adaptability to manufacture in automated factories. The winning approach must also rate highly in environmental potential, safety, availability factor, lifetime, small 0 and M costs, and no possibility of utility-disabling accidents.

  16. Fusion development and technology

    SciTech Connect

    Montgomery, D.B.

    1992-01-01

    This report discusses the following: superconducting magnet technology; high field superconductors; advanced magnetic system and divertor development; poloidal field coils; gyrotron development; commercial reactor studies--aries; ITER physics: alpha physics and alcator R D for ITER; lower hybrid current drive and heating in the ITER device; ITER superconducting PF scenario and magnet analysis; ITER systems studies; and safety, environmental and economic factors in fusion development.

  17. Is there hope for fusion

    SciTech Connect

    Fowler, T.K. . Dept. of Nuclear Engineering)

    1990-04-12

    From the outset in the 1950's, fusion research has been motivated by environmental concerns as well as long-term fuel supply issues. Compared to fossil fuels both fusion and fission would produce essentially zero emissions to the atmosphere. Compared to fission, fusion reactors should offer high demonstrability of public protection from accidents and a substantial amelioration of the radioactive waste problem. Fusion still requires lengthy development, the earliest commercial deployment being likely to occur around 2025--2050. However, steady scientific progress is being made and there is a wide consensus that it is time to plan large-scale engineering development. A major international effort, called the International Thermonuclear Experimental Reactor (ITER), is being carried out under IAEA auspices to design the world's first fusion engineering test reactor, which could be constructed in the 1990's. 4 figs., 3 tabs.

  18. Image fusion

    NASA Technical Reports Server (NTRS)

    Pavel, M.

    1993-01-01

    The topics covered include the following: a system overview of the basic components of a system designed to improve the ability of a pilot to fly through low-visibility conditions such as fog; the role of visual sciences; fusion issues; sensor characterization; sources of information; image processing; and image fusion.

  19. Fusion Power.

    ERIC Educational Resources Information Center

    Dingee, David A.

    1979-01-01

    Discusses the extraordinary potential, the technical difficulties, and the financial problems that are associated with research and development of fusion power plants as a major source of energy. (GA)

  20. Proton Collimators for Fusion Reactors

    NASA Technical Reports Server (NTRS)

    Miley, George H.; Momota, Hiromu

    2003-01-01

    Proton collimators have been proposed for incorporation into inertial-electrostatic-confinement (IEC) fusion reactors. Such reactors have been envisioned as thrusters and sources of electric power for spacecraft and as sources of energetic protons in commercial ion-beam applications.

  1. Overview of fusion reactor safety

    NASA Astrophysics Data System (ADS)

    Cohen, S.; Crocker, J. G.

    Use of deuterium-tritium fusion reactors requires examination of several major safety and environmental issues: (1) tritium inventory control; (2) neutron activation of structural materials, fluid streams and reactor hall environment; (3) release of radioactivity from energy sources including lithium spill reactions, superconducting magnet stored energy release, and plasma disruptions; (4) high magnetic and electromagnetic fields associated with fusion reactor superconducting magnets and radio frequency heating devices; and (5) handling and disposal of radioactive waste. Early recognition of potential safety problems with fusion reactors provides the opportunity for improvement in design and materials to eliminate or greatly reduce these problems. With an early start in this endeavor, fusion should be among the lower risk technologies for generation of commercial electrical power.

  2. Laser fusion

    SciTech Connect

    Smit, W.A.; Boskma, P.

    1980-12-01

    Unrestricted laser fusion offers nations an opportunity to circumvent arms control agreements and develop thermonuclear weapons. Early laser weapons research sought a clean radiation-free bomb to replace the fission bomb, but this was deceptive because a fission bomb was needed to trigger the fusion reaction and additional radioactivity was induced by generating fast neutrons. As laser-implosion experiments focused on weapons physics, simulating weapons effects, and applications for new weapons, the military interest shifted from developing a laser-ignited hydrogen bomb to more sophisticated weapons and civilian applications for power generation. Civilian and military research now overlap, making it possible for several countries to continue weapons activities and permitting proliferation of nuclear weapons. These countries are reluctant to include inertial confinement fusion research in the Non-Proliferation Treaty. 16 references. (DCK)

  3. Adjoint affine fusion and tadpoles

    NASA Astrophysics Data System (ADS)

    Urichuk, Andrew; Walton, Mark A.

    2016-06-01

    We study affine fusion with the adjoint representation. For simple Lie algebras, elementary and universal formulas determine the decomposition of a tensor product of an integrable highest-weight representation with the adjoint representation. Using the (refined) affine depth rule, we prove that equally striking results apply to adjoint affine fusion. For diagonal fusion, a coefficient equals the number of nonzero Dynkin labels of the relevant affine highest weight, minus 1. A nice lattice-polytope interpretation follows and allows the straightforward calculation of the genus-1 1-point adjoint Verlinde dimension, the adjoint affine fusion tadpole. Explicit formulas, (piecewise) polynomial in the level, are written for the adjoint tadpoles of all classical Lie algebras. We show that off-diagonal adjoint affine fusion is obtained from the corresponding tensor product by simply dropping non-dominant representations.

  4. Lunar Helium-3 and Fusion Power

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The NASA Office of Exploration sponsored the NASA Lunar Helium-3 and Fusion Power Workshop. The meeting was held to understand the potential of using He-3 from the moon for terrestrial fusion power production. It provided an overview, two parallel working sessions, a review of sessions, and discussions. The lunar mining session concluded that mining, beneficiation, separation, and return of He-3 from the moon would be possible but that a large scale operation and improved technology is required. The fusion power session concluded that: (1) that He-3 offers significant, possibly compelling, advantages over fusion of tritium, principally increased reactor life, reduced radioactive wastes, and high efficiency conversion, (2) that detailed assessment of the potential of the D/He-3 fuel cycle requires more information, and (3) D/He-3 fusion may be best for commercial purposes, although D/T fusion is more near term.

  5. Cold fusion, Alchemist's dream

    SciTech Connect

    Clayton, E.D.

    1989-09-01

    In this report the following topics relating to cold fusion are discussed: muon catalysed cold fusion; piezonuclear fusion; sundry explanations pertaining to cold fusion; cosmic ray muon catalysed cold fusion; vibrational mechanisms in excited states of D{sub 2} molecules; barrier penetration probabilities within the hydrogenated metal lattice/piezonuclear fusion; branching ratios of D{sub 2} fusion at low energies; fusion of deuterons into {sup 4}He; secondary D+T fusion within the hydrogenated metal lattice; {sup 3}He to {sup 4}He ratio within the metal lattice; shock induced fusion; and anomalously high isotopic ratios of {sup 3}He/{sup 4}He.

  6. Advanced commercial tokamak study

    SciTech Connect

    Thomson, S.L.; Dabiri, A.E.; Keeton, D.C.; Brown, T.G.; Bussell, G.T.

    1985-12-01

    Advanced commercial tokamak studies were performed by the Fusion Engineering Design Center (FEDC) as a participant in the Tokamak Power Systems Studies (TPSS) project coordinated by the Office of Fusion Energy. The FEDC studies addressed the issues of tokamak reactor cost, size, and complexity. A scoping study model was developed to determine the effect of beta on tokamak economics, and it was found that a competitive cost of electricity could be achieved at a beta of 10 to 15%. The implications of operating at a beta of up to 25% were also addressed. It was found that the economics of fusion, like those of fission, improve as unit size increases. However, small units were found to be competitive as elements of a multiplex plant, provided that unit cost and maintenance time reductions are realized for the small units. The modular tokamak configuration combined several new approaches to develop a less complex and lower cost reactor. The modular design combines the toroidal field coil with the reactor structure, locates the primary vacuum boundary at the reactor cell wall, and uses a vertical assembly and maintenance approach. 12 refs., 19 figs.

  7. Inertial fusion: strategy and economic potential

    SciTech Connect

    Nuckolls, J.H.

    1983-01-01

    Inertial fusion must demonstrate that the high target gains required for practical fusion energy can be achieved with driver energies not larger than a few megajoules. Before a multi-megajoule scale driver is constructed, inertial fusion must provide convincing experimental evidence that the required high target gains are feasible. This will be the principal objective of the NOVA laser experiments. Implosions will be conducted with scaled targets which are nearly hydrodynamically equivalent to the high gain target implosions. Experiments which demonstrate high target gains will be conducted in the early nineties when multi-megajoule drivers become available. Efficient drivers will also be demonstrated by this time period. Magnetic fusion may demonstrate high Q at about the same time as inertial fusion demonstrates high gain. Beyond demonstration of high performance fusion, economic considerations will predominate. Fusion energy will achieve full commercial success when it becomes cheaper than fission and coal. Analysis of the ultimate economic potential of inertial fusion suggests its costs may be reduced to half those of fission and coal. Relative cost escalation would increase this advantage. Fusions potential economic advantage derives from two fundamental properties: negligible fuel costs and high quality energy (which makes possible more efficient generation of electricity).

  8. Protoplast Fusion

    PubMed Central

    Yamada, Yasuyuki; Hara, Yasuhiro; Katagi, Hiroaki; Senda, Mitsugi

    1980-01-01

    The relation between the composition of the phospholipid molecular species in a cell membrane and the velocity of protoplast fusion was studied using cells cultured at a low temperature (10 C). Cells cultured at a low temperature contained larger proportions of phospholipids of low phase transition point, the 1,2-dilinoleoyl-type, than those cultured at a normal temperature (25 C). When treated with polyethylene glycol 6000, protoplasts from cells cultured at 10 C fused and progressed to the fused sphere stage more rapidly than did those from cells cultured at 25 C. PMID:16661339

  9. Splenogonadal fusion.

    PubMed

    Tsingoglou, S; Wilkinson, A W

    1976-04-01

    The fusion between splenic tissue and the left gonad or the derivatives of the left mesonephros is a rare congenital anomaly first described in detail by Pommer in 1887/9 and divided into two forms by Putschar and Manion in 1956. In the first or continuous type a cord of splenic or fibrous tissue connects the spleen and the gonadalmesonephric structures. In the second type the fused splenomesonephric structures have lost continuity with the main spleen. An example of the continuous form is presented and the previous reports are briefly reviewed.

  10. Commercial Crew

    NASA Video Gallery

    Phil McAlister delivers a presentation by the Commercial Crew (CC) study team on May 25, 2010, at the NASA Exploration Enterprise Workshop held in Galveston, TX. The purpose of this workshop was to...

  11. Space Commercialization

    NASA Technical Reports Server (NTRS)

    Martin, Gary L.

    2011-01-01

    A robust and competitive commercial space sector is vital to continued progress in space. The United States is committed to encouraging and facilitating the growth of a U.S. commercial space sector that supports U.S. needs, is globally competitive, and advances U.S. leadership in the generation of new markets and innovation-driven entrepreneurship. Energize competitive domestic industries to participate in global markets and advance the development of: satellite manufacturing; satellite-based services; space launch; terrestrial applications; and increased entrepreneurship. Purchase and use commercial space capabilities and services to the maximum practical extent Actively explore the use of inventive, nontraditional arrangements for acquiring commercial space goods and services to meet United States Government requirements, including measures such as public-private partnerships, . Refrain from conducting United States Government space activities that preclude, discourage, or compete with U.S. commercial space activities. Pursue potential opportunities for transferring routine, operational space functions to the commercial space sector where beneficial and cost-effective.

  12. Role of Fusion Energy in a Sustainable Global Energy Strategy

    SciTech Connect

    Sheffield, J.

    2001-03-07

    Fusion can play an important role in sustainable global energy because it has an available and unlimited fuel supply and location not restricted by climate or geography. Further, it emits no greenhouse gases. It has no potential for large energy releases in an accident, and no need for more than about 100 years retention for radioactive waste disposal. Substantial progress in the realization of fusion energy has been made during the past 20 years of research. It is now possible to produce significant amounts of energy from controlled deuterium and tritium (DT) reactions in the laboratory. This has led to a growing confidence in our ability to produce burning plasmas with significant energy gain in the next generation of fusion experiments. As success in fusion facilities has underpinned the scientific feasibility of fusion, the high cost of next-step fusion facilities has led to a shift in the focus of international fusion research towards a lower cost development path and an attractive end product. The increasing data base from fusion research allows conceptual fusion power plant studies, of both magnetic and inertial confinement approaches to fusion, to translate commercial requirements into the design features that must be met if fusion is to play a role in the world's energy mix; and identify key R and D items; and benchmark progress in fusion energy development. This paper addresses the question, ''Is mankind closer or farther away from controlled fusion than a few decades ago?'' We review the tremendous scientific progress during the last 10 years. We use the detailed engineering design activities of burning plasma experiments as well as conceptual fusion power plant studies to describe our visions of attractive fusion power plants. We use these studies to compare technical requirements of an attractive fusion system with present achievements and to identify remaining technical challenges for fusion. We discuss scenarios for fusion energy deployment in the

  13. EDITORIAL: Safety aspects of fusion power plants

    NASA Astrophysics Data System (ADS)

    Kolbasov, B. N.

    2007-07-01

    This special issue of Nuclear Fusion contains 13 informative papers that were initially presented at the 8th IAEA Technical Meeting on Fusion Power Plant Safety held in Vienna, Austria, 10-13 July 2006. Following recommendation from the International Fusion Research Council, the IAEA organizes Technical Meetings on Fusion Safety with the aim to bring together experts to discuss the ongoing work, share new ideas and outline general guidance and recommendations on different issues related to safety and environmental (S&E) aspects of fusion research and power facilities. Previous meetings in this series were held in Vienna, Austria (1980), Ispra, Italy (1983), Culham, UK (1986), Jackson Hole, USA (1989), Toronto, Canada (1993), Naka, Japan (1996) and Cannes, France (2000). The recognized progress in fusion research and technology over the last quarter of a century has boosted the awareness of the potential of fusion to be a practically inexhaustible and clean source of energy. The decision to construct the International Thermonuclear Experimental Reactor (ITER) represents a landmark in the path to fusion power engineering. Ongoing activities to license ITER in France look for an adequate balance between technological and scientific deliverables and complying with safety requirements. Actually, this is the first instance of licensing a representative fusion machine, and it will very likely shape the way in which a more common basis for establishing safety standards and policies for licensing future fusion power plants will be developed. Now that ITER licensing activities are underway, it is becoming clear that the international fusion community should strengthen its efforts in the area of designing the next generations of fusion power plants—demonstrational and commercial. Therefore, the 8th IAEA Technical Meeting on Fusion Safety focused on the safety aspects of power facilities. Some ITER-related safety issues were reported and discussed owing to their potential

  14. Thermonuclear Fusion: An Energy Source for the Future

    ERIC Educational Resources Information Center

    Drummond, William E.

    1973-01-01

    Discusses current research in thermonuclear fusion with particular emphasis on the problem of confining hot plasma. Recent experiments indicate that magnetic bottles called tokamaks may achieve the necessary confinement times, and this break-through has given renewed optimism to the feasibility of commercial fusion power by the turn of the…

  15. Commercial Fishing.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee. Div. of Vocational Education.

    This document is a curriculum framework for a program in commercial fishing to be taught in Florida secondary and postsecondary institutions. This outline covers the major concepts/content of the program, which is designed to prepare students for employment in occupations with titles such as net fishers, pot fishers, line fishers, shrimp boat…

  16. Commercial applications

    NASA Technical Reports Server (NTRS)

    Togai, Masaki

    1990-01-01

    Viewgraphs on commercial applications of fuzzy logic in Japan are presented. Topics covered include: suitable application area of fuzzy theory; characteristics of fuzzy control; fuzzy closed-loop controller; Mitsubishi heavy air conditioner; predictive fuzzy control; the Sendai subway system; automatic transmission; fuzzy logic-based command system for antilock braking system; fuzzy feed-forward controller; and fuzzy auto-tuning system.

  17. Commercial Art.

    ERIC Educational Resources Information Center

    Vassallo, Thomas

    This curriculum guide provides materials for a competency-based course in commercial art at the secondary level. The curriculum design uses the curriculum infused model for the teaching of basic skills as part of vocational education and demonstrates the relationship of vocationally related skills to communication, mathematics, and science…

  18. Fusion energy

    NASA Astrophysics Data System (ADS)

    1990-09-01

    The main purpose of the International Thermonuclear Experimental Reactor (ITER) is to develop an experimental fusion reactor through the united efforts of many technologically advanced countries. The ITER terms of reference, issued jointly by the European Community, Japan, the USSR, and the United States, call for an integrated international design activity and constitute the basis of current activities. Joint work on ITER is carried out under the auspices of the International Atomic Energy Agency (IAEA), according to the terms of quadripartite agreement reached between the European Community, Japan, the USSR, and the United States. The site for joint technical work sessions is at the Max Planck Institute of Plasma Physics. Garching, Federal Republic of Germany. The ITER activities have two phases: a definition phase performed in 1988 and the present design phase (1989 to 1990). During the definition phase, a set of ITER technical characteristics and supporting research and development (R and D) activities were developed and reported. The present conceptual design phase of ITER lasts until the end of 1990. The objectives of this phase are to develop the design of ITER, perform a safety and environmental analysis, develop site requirements, define future R and D needs, and estimate cost, manpower, and schedule for construction and operation. A final report will be submitted at the end of 1990. This paper summarizes progress in the ITER program during the 1989 design phase.

  19. Fusion energy

    SciTech Connect

    Not Available

    1990-09-01

    The main purpose of the International Thermonuclear Experimental Reactor (ITER) is to develop an experimental fusion reactor through the united efforts of many technologically advanced countries. The ITER terms of reference, issued jointly by the European Community, Japan, the USSR, and the United States, call for an integrated international design activity and constitute the basis of current activities. Joint work on ITER is carried out under the auspices of the International Atomic Energy Agency (IAEA), according to the terms of quadripartite agreement reached between the European Community, Japan, the USSR, and the United States. The site for joint technical work sessions is at the MaxPlanck Institute of Plasma Physics. Garching, Federal Republic of Germany. The ITER activities have two phases: a definition phase performed in 1988 and the present design phase (1989--1990). During the definition phase, a set of ITER technical characteristics and supporting research and development (R D) activities were developed and reported. The present conceptual design phase of ITER lasts until the end of 1990. The objectives of this phase are to develop the design of ITER, perform a safety and environmental analysis, develop site requirements, define future R D needs, and estimate cost, manpower, and schedule for construction and operation. A final report will be submitted at the end of 1990. This paper summarizes progress in the ITER program during the 1989 design phase.

  20. Trends in fusion reactor safety research

    SciTech Connect

    Herring, J.S.; Holland, D.F.; Piet, S.J.

    1991-01-01

    Fusion has the potential to be an attractive energy source. From the safety and environmental perspective, fusion must avoid concerns about catastrophic accidents and unsolvable waste disposal. In addition, fusion must achieve an acceptable level of risk from operational accidents that result in public exposure and economic loss. Finally, fusion reactors must control routine radioactive effluent, particularly tritium. Major progress in achieving this potential rests on development of low-activation materials or alternative fuels. The safety and performance of various material choices and fuels for commercial fusion reactors can be investigated relatively inexpensively through reactor design studies. These studies bring together experts in a wide range of backgrounds and force the group to either agree on a reactor design or identify areas for further study. Fusion reactors will be complex with distributed radioactive inventories. The next generation of experiments will be critical in demonstrating that acceptable levels of safe operation can be achieved. These machines will use materials which are available today and for which a large database exists (e.g. for 316 stainless steel). Researchers have developed a good understanding of the risks associated with operation of these devices. Specifically, consequences from coolant system failures, loss of vacuum events, tritium releases, and liquid metal reactions have been studied. Recent studies go beyond next step designs and investigate commercial reactor concerns including tritium release and liquid metal reactions. 18 refs.

  1. Magnetized Target Fusion in Advanced Propulsion Research

    NASA Technical Reports Server (NTRS)

    Cylar, Rashad

    2003-01-01

    The Magnetized Target Fusion (MTF) Propulsion lab at NASA Marshall Space Flight Center in Huntsville, Alabama has a program in place that has adopted to attempt to create a faster, lower cost and more reliable deep space transportation system. In this deep space travel the physics and development of high velocity plasma jets must be understood. The MTF Propulsion lab is also in attempt to open up the solar system for human exploration and commercial use. Fusion, as compared to fission, is just the opposite. Fusion involves the light atomic nuclei combination to produce denser nuclei. In the process, the energy is created by destroying the mass according to the distinguished equation: E = mc2 . Fusion energy development is being pursued worldwide as a very sustainable form of energy that is environmentally friendly. For the purposes of space exploration fusion reactions considered include the isotopes of hydrogen-deuterium (D2) and tritium (T3). Nuclei have an electrostatic repulsion between them and in order for the nuclei to fuse this repulsion must be overcome. One technique to bypass repulsion is to heat the nuclei to very high temperatures. The temperatures vary according to the type of reactions. For D-D reactions, one billion degrees Celsius is required, and for D-T reactions, one hundred million degrees is sufficient. There has to be energy input for useful output to be obtained form the fusion To make fusion propulsion practical, the mass, the volume, and the cost of the equipment to produce the reactions (generally called the reactor) need to be reduced by an order of magnitude or two from the state-of-the-art fusion machines. Innovations in fusion schemes are therefore required, especially for obtaining thrust for propulsive applications. Magnetized target fusion (MTF) is one of the innovative fusion concepts that have emerged over the last several years. MSFC is working with Los Alamos National Laboratory and other research groups in studying the

  2. Ch. 37, Inertial Fusion Energy Technology

    SciTech Connect

    Moses, E

    2010-06-09

    Nuclear fission, nuclear fusion, and renewable energy (including biofuels) are the only energy sources capable of satisfying the Earth's need for power for the next century and beyond without the negative environmental impacts of fossil fuels. Substantially increasing the use of nuclear fission and renewable energy now could help reduce dependency on fossil fuels, but nuclear fusion has the potential of becoming the ultimate base-load energy source. Fusion is an attractive fuel source because it is virtually inexhaustible, widely available, and lacks proliferation concerns. It also has a greatly reduced waste impact, and no danger of runaway reactions or meltdowns. The substantial environmental, commercial, and security benefits of fusion continue to motivate the research needed to make fusion power a reality. Replicating the fusion reactions that power the sun and stars to meet Earth's energy needs has been a long-sought scientific and engineering challenge. In fact, this technological challenge is arguably the most difficult ever undertaken. Even after roughly 60 years of worldwide research, much more remains to be learned. the magnitude of the task has caused some to declare that fusion is 20 years away, and always will be. This glib criticism ignores the enormous progress that has occurred during those decades, progress inboth scientific understanding and essential technologies that has enabled experiments producing significant amounts of fusion energy. For example, more than 15 megawatts of fusion power was produced in a pulse of about half a second. Practical fusion power plants will need to produce higher powers averaged over much longer periods of time. In addition, the most efficient experiments to date have required using about 50% more energy than the resulting fusion reaction generated. That is, there was no net energy gain, which is essential if fusion energy is to be a viable source of electricity. The simplest fusion fuels, the heavy isotopes of

  3. Criteria for practical fusion power systems: Report from the EPRI fusion panel

    NASA Astrophysics Data System (ADS)

    Kaslow, J.; Brown, M.; Hirsch, R.; izzo, R.; McCann, J.; McCloud, D.; Muston, B.; Peterson, A.; Rosen, S.; Schneider, T.; Skrgic, P.; Snow, B.

    1994-09-01

    Electric utilities are keenly interested in the promise of fusion: large-scale electricity production anywhere, with virtually no natural resource depletion or environmental pollution. To expedite development of commercially viable fusion systems, the Electric Power Research Institute (EPRI)—the R&D wing of the U.S. electric utility industry—recently convened a panel of top utility R&D managers and executive officers to identify the key criteria that must be met by fusion plants in order to be acceptable to utilities. The panel's findings, summarized in this report, emphasize competitive economics, positive public perception, and regulatory simplicity.

  4. National mirror fusion program plan

    NASA Astrophysics Data System (ADS)

    Borchers, R. R.; Vanatta, C. M.

    1980-01-01

    Experiments are under way in the Tandem Mirror Experiment (TMX) facility at Livermore. Recently this idea was greatly improved by incorporating a new element called the thermal barrier, a concept that promises a higher power gain factor (Q = 10 to 20) with much less demanding neutral beam and magnet technology and a higher fusion power density in the reactor. In addition to the tandem-mirror experiments in TMX, a new attempt will be made in the Beta 2 facility during FY 1980 to create and sustain a field-reversed mirror configuration, which is a different mirror fusion approach that could lead to early commercialization of small reactors. The plan presented here is designed to exploit the results of these and other mirror experiments and theoretical developments toward a variety of applications. The main objective is electric power generation.

  5. Soldier systems sensor fusion

    NASA Astrophysics Data System (ADS)

    Brubaker, Kathryne M.

    1998-08-01

    This paper addresses sensor fusion and its applications in emerging Soldier Systems integration and the unique challenges associated with the human platform. Technology that,provides the highest operational payoff in a lightweight warrior system must not only have enhanced capabilities, but have low power components resulting in order of magnitude reductions coupled with significant cost reductions. These reductions in power and cost will be achieved through partnership with industry and leveraging of commercial state of the art advancements in microelectronics and power sources. As new generation of full solution fire control systems (to include temperature, wind and range sensors) and target acquisition systems will accompany a new generation of individual combat weapons and upgrade existing weapon systems. Advanced lightweight thermal, IR, laser and video senors will be used for surveillance, target acquisition, imaging and combat identification applications. Multifunctional sensors will provide embedded training features in combat configurations allowing the soldier to 'train as he fights' without the traditional cost and weight penalties associated with separate systems. Personal status monitors (detecting pulse, respiration rate, muscle fatigue, core temperature, etc.) will provide commanders and highest echelons instantaneous medical data. Seamless integration of GPS and dead reckoning (compass and pedometer) and/or inertial sensors will aid navigation and increase position accuracy. Improved sensors and processing capability will provide earlier detection of battlefield hazards such as mines, enemy lasers and NBC (nuclear, biological, chemical) agents. Via the digitized network the situational awareness database will automatically be updated with weapon, medical, position and battlefield hazard data. Soldier Systems Sensor Fusion will ultimately establish each individual soldier as an individual sensor on the battlefield.

  6. Commercial Capaciflector

    NASA Technical Reports Server (NTRS)

    Vranish, John M.

    1991-01-01

    A capacitive proximity/tactile sensor with unique performance capabilities ('capaciflector' or capacitive reflector) is being developed by NASA/Goddard Space Flight Center (GSFC) for use on robots and payloads in space in the interests of safety, efficiency, and ease of operation. Specifically, this sensor will permit robots and their attached payloads to avoid collisions in space with humans and other objects and to dock these payloads in a cluttered environment. The sensor is simple, robust, and inexpensive to manufacture with obvious and recognized commercial possibilities. Accordingly, NASA/GSFC, in conjunction with industry, is embarking on an effort to 'spin' this technology off into the private sector. This effort includes prototypes aimed at commercial applications. The principles of operation of these prototypes are described along with hardware, software, modelling, and test results. The hardware description includes both the physical sensor in terms of a flexible printed circuit board and the electronic circuitry. The software description will include filtering and detection techniques. The modelling will involve finite element electric field analysis and will underline techniques used for design optimization.

  7. Viral membrane fusion.

    PubMed

    Harrison, Stephen C

    2015-05-01

    Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the agents that fulfill this catalytic function. Despite a variety of molecular architectures, these proteins facilitate fusion by essentially the same generic mechanism. Stimulated by a signal associated with arrival at the cell to be infected (e.g., receptor or co-receptor binding, proton binding in an endosome), they undergo a series of conformational changes. A hydrophobic segment (a "fusion loop" or "fusion peptide") engages the target-cell membrane and collapse of the bridging intermediate thus formed draws the two membranes (virus and cell) together. We know of three structural classes for viral fusion proteins. Structures for both pre- and postfusion conformations of illustrate the beginning and end points of a process that can be probed by single-virion measurements of fusion kinetics.

  8. Magneto-Inertial Fusion

    DOE PAGES

    Wurden, G. A.; Hsu, S. C.; Intrator, T. P.; Grabowski, T. C.; Degnan, J. H.; Domonkos, M.; Turchi, P. J.; Campbell, E. M.; Sinars, D. B.; Herrmann, M. C.; et al

    2015-11-17

    In this community white paper, we describe an approach to achieving fusion which employs a hybrid of elements from the traditional magnetic and inertial fusion concepts, called magneto-inertial fusion (MIF). The status of MIF research in North America at multiple institutions is summarized including recent progress, research opportunities, and future plans.

  9. Hot and cold fusion

    SciTech Connect

    Not Available

    1990-08-01

    This article presents an overview of research in cold fusion research and development in cold fusion at the Tokomak Fusion Test Reactor at the Princeton Plasma Physics Lab, and at the inertial containment facility at Lawrence Livermore National Lab. is described.

  10. The need and prospects for improved fusion reactors

    NASA Astrophysics Data System (ADS)

    Krakowski, R. A.; Miller, R. L.; Hagenson, R. L.

    1986-09-01

    Conceptual fusion reactor studies over the past 10-15 yr have projected systems that may be too large, complex, and costly to be of commercial interest. One main direction for improved fusion reactors points toward smaller, higher-power-density approaches. First-order economic issues (i.e., unit direct cost and cost of electricity) are used to support the need for more compact fusion reactors. The results of a number of recent conceptual designs of reversed-field pinch, spheromak, and tokamak fusion reactors are summarized as examples of more compact approaches. While a focus has been placed on increasing the fusion-power-core mass power density beyond the minimum economic threshold of 100-200 kWe/tonne, other means by which the overall attractiveness of fusion as a long-term energy source are also addressed.

  11. Visual programming environment for multisensor data fusion

    NASA Astrophysics Data System (ADS)

    Hall, David L.; Kasmala, Gerald

    1996-06-01

    In recent years, numerous multisensor data fusion systems have been developed for a wide variety of applications. Defense related applications include; automatic target recognition systems, identification-friend-foe-neutral, automated situation assessment and threat assessment systems, and systems for smart weapons. Non-defense applications include; robotics, condition-based maintenance, environmental monitoring, and medical diagnostics. For each of these applications, multiple sensor data are combined to achieve inferences which are not generally possible using only a single sensor. Implementation of these data fusion systems often involves a significant amount of effort. In particular, software must be developed for components such as data base access, human computer interfaces and displays, communication software, and data fusion algorithms. While commercial software packages exist to assist development of data bases, communications, and human computer interfaces, there are no general purpose packages available to support the implementation of the data fusion algorithms. This paper describes a visual programming tool developed to assist in rapid prototyping of data fusion systems. This toolkit is modeled after the popular tool, Khoros, used by the image processing community. The tool described here is written in visual C, and provides the capability to rapidly implement and apply data fusion algorithms. An application to condition based maintenance is described.

  12. Magnetized Target Fusion: Prospects for Low-Cost Fusion Energy

    NASA Technical Reports Server (NTRS)

    Siemon, Richard E.; Turchi, Peter J.; Barnes, Daniel C.; Degnan, James; Parks, Paul; Ryutov, Dmitri D.; Thio, Y. C. Francis; Schafer, Charles (Technical Monitor)

    2001-01-01

    Magnetized Target Fusion (MTF) has attracted renewed interest in recent years because it has the potential to resolve one of the major problems with conventional fusion energy research - the high cost of facilities to do experiments and in general develop practical fusion energy. The requirement for costly facilities can be traced to fundamental constraints. The Lawson condition implies large system size in the case of conventional magnetic confinement, or large heating power in the case of conventional inertial confinement. The MTF approach is to use much higher fuel density than with conventional magnetic confinement (corresponding to megabar pressures), which results in a much-reduced system size to achieve Lawson conditions. Intrinsically the system must be pulsed because the pressures exceed the strength of any known material. To facilitate heating the fuel (or "target") to thermonuclear conditions with a high-power high-intensity source of energy, magnetic fields are used to insulate the high-pressure fuel from material surroundings (thus "magnetized target"). Because of magnetic insulation, the required heating power intensity is reduced by many orders of magnitude compared to conventional inertial fusion, even with relatively poor energy confinement in the magnetic field, such as that characterized by Bohm diffusion. In this paper we show semi-quantitatively why MTF-should allow fusion energy production without costly facilities within the same generally accepted physical constraints used for conventional magnetic and inertial fusion. We also briefly discuss potential applications of this technology ranging from nuclear rockets for space propulsion to a practical commercial energy system. Finally, we report on the exploratory research underway, and the interesting physics issues that arise in the MTF regime of parameters. Experiments at Los Alamos are focused on formation of a suitable plasma target for compression, utilizing the knowledge base for compact

  13. Viral membrane fusion

    SciTech Connect

    Harrison, Stephen C.

    2015-05-15

    Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the agents that fulfill this catalytic function. Despite a variety of molecular architectures, these proteins facilitate fusion by essentially the same generic mechanism. Stimulated by a signal associated with arrival at the cell to be infected (e.g., receptor or co-receptor binding, proton binding in an endosome), they undergo a series of conformational changes. A hydrophobic segment (a “fusion loop” or “fusion peptide”) engages the target-cell membrane and collapse of the bridging intermediate thus formed draws the two membranes (virus and cell) together. We know of three structural classes for viral fusion proteins. Structures for both pre- and postfusion conformations of illustrate the beginning and end points of a process that can be probed by single-virion measurements of fusion kinetics. - Highlights: • Viral fusion proteins overcome the high energy barrier to lipid bilayer merger. • Different molecular structures but the same catalytic mechanism. • Review describes properties of three known fusion-protein structural classes. • Single-virion fusion experiments elucidate mechanism.

  14. The fusion breeder

    NASA Astrophysics Data System (ADS)

    Moir, Ralph W.

    1982-10-01

    The fusion breeder is a fusion reactor designed with special blankets to maximize the transmutation by 14 MeV neutrons of uranium-238 to plutonium or thorium to uranium-233 for use as a fuel for fission reactors. Breeding fissile fuels has not been a goal of the U.S. fusion energy program. This paper suggests it is time for a policy change to make the fusion breeder a goal of the U.S. fusion program and the U.S. nuclear energy program. There is wide agreement that many approaches will work and will produce fuel for five equal-sized LWRs, and some approach as many as 20 LWRs at electricity costs within 20% of those at today's price of uranium (30/lb of U3O8). The blankets designed to suppress fissioning, called symbiotes, fusion fuel factories, or just fusion breeders, will have safety characteristics more like pure fusion reactors and will support as many as 15 equal power LWRs. The blankets designed to maximize fast fission of fertile material will have safety characteristics more like fission reactors and will support 5 LWRs. This author strongly recommends development of the fission suppressed blanket type, a point of view not agreed upon by everyone. There is, however, wide agreement that, to meet the market price for uranium which would result in LWR electricity within 20% of today's cost with either blanket type, fusion components can cost severalfold more than would be allowed for pure fusion to meet the goal of making electricity alone at 20% over today's fission costs. Also widely agreed is that the critical-path-item for the fusion breeder is fusion development itself; however, development of fusion breeder specific items (blankets, fuel cycle) should be started now in order to have the fusion breeder by the time the rise in uranium prices forces other more costly choices.

  15. Commercial applications

    NASA Astrophysics Data System (ADS)

    The near term (one to five year) needs of domestic and foreign commercial suppliers of radiochemicals and radiopharmaceuticals for electromagnetically separated stable isotopes are assessed. Only isotopes purchased to make products for sale and profit are considered. Radiopharmaceuticals produced from enriched stable isotopes supplied by the Calutron facility at ORNL are used in about 600,000 medical procedures each year in the United States. A temporary or permanent disruption of the supply of stable isotopes to the domestic radiopharmaceutical industry could curtail, if not eliminate, the use of such diagnostic procedures as the thallium heart scan, the gallium cancer scan, the gallium abscess scan, and the low radiation dose thyroid scan. An alternative source of enriched stable isotopes exist in the USSR. Alternative starting materials could, in theory, eventually be developed for both the thallium and gallium scans. The development of a new technology for these purposes, however, would take at least five years and would be expensive. Hence, any disruption of the supply of enriched isotopes from ORNL and the resulting unavailability of critical nuclear medicine procedures would have a dramatic negative effect on the level of health care in the United States.

  16. Commercial users panel

    NASA Technical Reports Server (NTRS)

    Byrd, Joseph S.; Flatau, Carl; Hodge, David C.; Hollis, Ralph; Leach, Eugene F.; Gilbert, Ray; Cleland, John; Leifer, Larry; Naser, Joseph; Schmuter, Samson D.

    1987-01-01

    The discussions of motives and requirements for telerobotics application demonstrated that, in many cases, lack of progress was a result not of limited opportunities but of inadequate mechanisms and resources for promoting opportunities. Support for this conclusion came from Telerobotics, Inc., one of the few companies devoted primarily to telerobot systems. They have produced units for such diverse applications as nuclear fusion research, particle accelerators, cryogenics, firefighting, marine biology/undersea systems and nuclear mobile robotics. Mr. Flatau offered evidence that telerobotics research is only rarely supported by the private sector and that it often presents a difficult market. Questions on the mechanisms contained within the NASA technology transfer process for promoting commercial opportunities were fielded by Ray Gilbert and Tom Walters. A few points deserve emphasis: (1) NASA/industry technology transfer occurs in both directions and NASA recognizes the opportunity to learn a great deal from industry in the fields of automation and robotics; (2) promotion of technology transfer projects takes a demand side approach, with requests to industry for specific problem identification. NASA then proposes possible solutions; and (3) comittment ofmotivated and technically qualified people on each end of a technology transfer is essential.

  17. Muon Catalyzed Fusion

    NASA Technical Reports Server (NTRS)

    Armour, Edward A.G.

    2007-01-01

    Muon catalyzed fusion is a process in which a negatively charged muon combines with two nuclei of isotopes of hydrogen, e.g, a proton and a deuteron or a deuteron and a triton, to form a muonic molecular ion in which the binding is so tight that nuclear fusion occurs. The muon is normally released after fusion has taken place and so can catalyze further fusions. As the muon has a mean lifetime of 2.2 microseconds, this is the maximum period over which a muon can participate in this process. This article gives an outline of the history of muon catalyzed fusion from 1947, when it was first realised that such a process might occur, to the present day. It includes a description of the contribution that Drachrnan has made to the theory of muon catalyzed fusion and the influence this has had on the author's research.

  18. Hybrid Fusion: The Only Viable Development Path for Tokamaks?

    NASA Astrophysics Data System (ADS)

    Manheimer, Wallace

    2009-03-01

    The world needs a great deal of carbon free energy, and soon, for civilization to continue. Fusion's goal is to develop such a carbon free energy source. For the last 4 decades, tokamaks have been the best magnetic fusion has to offer. But what if its development stops short of commercial fusion? This paper introduces `conservative design principles' for tokamaks. These are very simple, are reasonably based in theory, and have always constrained tokamak operation. Assuming they continue to do so, it is unlikely that tokamaks will ever make it as commercial reactors. This is independent of their confinement properties. However because of the large additional gain in hybrid fusion, tokamaks reactors look like they can make it as hybrid fuel producers, and provide large scale power by mid century or shortly thereafter.

  19. Status of fusion maintenance

    SciTech Connect

    Fuller, G.M.

    1984-01-01

    Effective maintenance will be an essential ingredient in determining fusion system productivity. This level of productivity will result only after close attention is paid to the entire system as an entity and appropriate integration of the elements is made. The status of fusion maintenance is reviewed in the context of the entire system. While there are many challenging developmental tasks ahead in fusion maintenance, the required technologies are available in several high-technology industries, including nuclear fission.

  20. Fusion: The controversy continues

    SciTech Connect

    1989-07-01

    Nuclear fusion-the power of the stars that promises mankind an inexhaustible supply of energy-seems concurrently much closer and still distant this month. The recent flurry of announcements concerning the achievement of a cold fusion reaction has-if nothing else-underscored the historic importance of the basic fusion reaction which uses hydrogen ions to fuel an energy-producing reaction.

  1. Magnetic-confinement fusion

    NASA Astrophysics Data System (ADS)

    Ongena, J.; Koch, R.; Wolf, R.; Zohm, H.

    2016-05-01

    Our modern society requires environmentally friendly solutions for energy production. Energy can be released not only from the fission of heavy nuclei but also from the fusion of light nuclei. Nuclear fusion is an important option for a clean and safe solution for our long-term energy needs. The extremely high temperatures required for the fusion reaction are routinely realized in several magnetic-fusion machines. Since the early 1990s, up to 16 MW of fusion power has been released in pulses of a few seconds, corresponding to a power multiplication close to break-even. Our understanding of the very complex behaviour of a magnetized plasma at temperatures between 150 and 200 million °C surrounded by cold walls has also advanced substantially. This steady progress has resulted in the construction of ITER, a fusion device with a planned fusion power output of 500 MW in pulses of 400 s. ITER should provide answers to remaining important questions on the integration of physics and technology, through a full-size demonstration of a tenfold power multiplication, and on nuclear safety aspects. Here we review the basic physics underlying magnetic fusion: past achievements, present efforts and the prospects for future production of electrical energy. We also discuss questions related to the safety, waste management and decommissioning of a future fusion power plant.

  2. Meteorite fusion crust variability.

    NASA Astrophysics Data System (ADS)

    Thaisen, Kevin G.; Taylor, Lawrence A.

    2009-06-01

    Two assumptions commonly employed in meteorite interpretation are that fusion crust compositions represent the bulk-rock chemistry of the interior meteorite and that the vesicles within the fusion crust result from the release of implanted solar wind volatiles. Electron microprobe analyses of thin sections from lunar meteorite Miller Range (MIL) 05035 and eucrite Bates Nunataks (BTN) 00300 were performed to determine if the chemical compositions of the fusion crust varied and/or represented the published bulk rock composition. It was determined that fusion crust compositions are significantly influenced by the incorporation of fragments from the substrate, and by the composition and grain size of those minerals. Because of compositional heterogeneities throughout the meteorite, one cannot assume that fusion crust composition represents the bulk rock composition. If the compositional variability within the fusion crust and mineralogical differences among thin sections goes unnoticed, then the perceived composition and petrogenetic models of formation will be incorrect. The formation of vesicles within these fusion crusts were also compared to current theories attributing vesicles to a solar wind origin. Previous work from the STONE-5 experiment, where terrestrial rocks were exposed on the exterior of a spacecraft heatshield, produced a vesicular fusion crust without prolonged exposure to solar wind suggesting that the high temperatures experienced by a meteorite during passage through the Earth's atmosphere are sufficient to cause boiling of the melt. Therefore, the assumption that all vesicles found within a fusion crust are due to the release of implanted volatiles of solar wind may not be justified.

  3. Fusion silicide coatings for tantalum alloys.

    NASA Technical Reports Server (NTRS)

    Warnock, R. V.; Stetson, A. R.

    1972-01-01

    Calculation of the performance of fusion silicide coatings under simulated atmospheric reentry conditions to a maximum temperature of 1810 K (2800 F). Both recently developed and commercially available coatings are included. Data are presented on oxidation rate with and without intentional defecting, the influence of the coatings on the ductile-brittle bend transition temperature, and the mechanical properties. Coatings appear capable of affording protection for at least 100 simulated cycles to 2600 F and 63 cycles to 2800 F.

  4. Recurrent read-through fusion transcripts in breast cancer.

    PubMed

    Varley, Katherine E; Gertz, Jason; Roberts, Brian S; Davis, Nicholas S; Bowling, Kevin M; Kirby, Marie K; Nesmith, Amy S; Oliver, Patsy G; Grizzle, William E; Forero, Andres; Buchsbaum, Donald J; LoBuglio, Albert F; Myers, Richard M

    2014-07-01

    Read-through fusion transcripts that result from the splicing of two adjacent genes in the same coding orientation are a recently discovered type of chimeric RNA. We sought to determine if read-through fusion transcripts exist in breast cancer. We performed paired-end RNA-seq of 168 breast samples, including 28 breast cancer cell lines, 42 triple negative breast cancer primary tumors, 42 estrogen receptor positive (ER+) breast cancer primary tumors, and 56 non-malignant breast tissue samples. We analyzed the sequencing data to identify breast cancer associated read-through fusion transcripts. We discovered two recurrent read-through fusion transcripts that were identified in breast cancer cell lines, confirmed across breast cancer primary tumors, and were not detected in normal tissues (SCNN1A-TNFRSF1A and CTSD-IFITM10). Both fusion transcripts use canonical splice sites to join the last splice donor of the 5' gene to the first splice acceptor of the 3' gene, creating an in-frame fusion transcript. Western blots indicated that the fusion transcripts are translated into fusion proteins in breast cancer cells. Custom small interfering RNAs targeting the CTSD-IFITM10 fusion junction reduced expression of the fusion transcript and reduced breast cancer cell proliferation. Read-through fusion transcripts between adjacent genes with different biochemical functions represent a new type of recurrent molecular defect in breast cancer that warrant further investigation as potential biomarkers and therapeutic targets. Both breast cancer associated fusion transcripts identified in this study involve membrane proteins (SCNN1A-TNFRSF1A and CTSD-IFITM10), which raises the possibility that they could be breast cancer-specific cell surface markers. PMID:24929677

  5. Bloch-symmetric fusion in PdD sub x

    SciTech Connect

    Chubb, T.A. ); Chubb, S.R. )

    1990-07-01

    A theory of solid-state fusion based on the formation of a D{sup +} Bose Bloch condensate (BBC) is summarized. The first step toward fusion is a coalescence reaction that converts a multiple-occupation state of chemical density into a state of nuclear density. In PdD{sub x}, conditions for formation of a BBC are favorable when x is near unity, due to avoidance of lattice strain energy that otherwise contributes to the chemical potential. Fusion obeys a boson in, boson out selection rule and avoids the proton and neutron fluxes of collision-induced fusion. Some cold fusion studies are compatible with the theory and indicate the possibility of largely radiation-free commercial nuclear power from an inexhaustible fuel supply.

  6. Fusion proteins as alternate crystallization paths to difficult structure problems

    NASA Technical Reports Server (NTRS)

    Carter, Daniel C.; Rueker, Florian; Ho, Joseph X.; Lim, Kap; Keeling, Kim; Gilliland, Gary; Ji, Xinhua

    1994-01-01

    The three-dimensional structure of a peptide fusion product with glutathione transferase from Schistosoma japonicum (SjGST) has been solved by crystallographic methods to 2.5 A resolution. Peptides or proteins can be fused to SjGST and expressed in a plasmid for rapid synthesis in Escherichia coli. Fusion proteins created by this commercial method can be purified rapidly by chromatography on immobilized glutathione. The potential utility of using SjGST fusion proteins as alternate paths to the crystallization and structure determination of proteins is demonstrated.

  7. Heavy ion fusion--Using heavy ions to make electricity

    SciTech Connect

    Celata, C.M.

    2004-03-15

    The idea of using nuclear fusion as a source of commercial electrical power has been pursued worldwide since the 1950s. Two approaches, using magnetic and inertial confinement of the reactants, are under study. This paper describes the difference between the two approaches, and discusses in more detail the heavy-ion-driven inertial fusion concept. A multibeam induction linear accelerator would be used to bring {approx}100 heavy ion beams to a few GeV. The beams would then heat and compress a target of solid D-T. This approach is unique among fusion concepts in its ability to protect the reaction chamber wall from neutrons and debris.

  8. Coatings for laser fusion

    SciTech Connect

    Lowdermilk, W.H.

    1981-12-18

    Optical coatings are used in lasers systems for fusion research to control beam propagation and reduce surface reflection losses. The performance of coatings is important in the design, reliability, energy output, and cost of the laser systems. Significant developments in coating technology are required for future lasers for fusion research and eventual power reactors.

  9. Fusion Science Education Outreach

    NASA Astrophysics Data System (ADS)

    Danielson, C. A.; DIII-D Education Group

    1996-11-01

    This presentation will focus on education outreach activities at General Atomics that have been expanded to include the general population on science education with a focus on fusion energy. Outreach materials are distributed upon request both nationally and internationally. These materials include a notebook containing copies of DIII--D tour panels, fusion poster, new fusion energy video, new fusion energy brochure, and the electromagnetic spectrum curriculum. The 1996 Fusion Forum (held in the House Caucus Room) included a student/ teacher lunch with Energy Secretary Hazel O'Leary and a private visit to the Forum exhibits. The continuing partnership with Kearny High School includes lectures, job shadowing, internship, equipment donations and an award-winning electric car-racing program. Development of distribution by CD of the existing interactive fusion energy kiosk and a virtual reality tour of the DIII--D facility are underway. The DIII--D fusion education WWW site includes e-mail addresses to ``Ask the Wizard,'' and/or receive GA's outreach materials. Steve Rodecker, a local science teacher, aided by DIII--D fusion staff, won his second Tapestry Award; he also was named the ``1995 National Science Teacher of the Year'' and will be present to share his experiences with the DIII--D educational outreach program.

  10. Controlled Nuclear Fusion.

    ERIC Educational Resources Information Center

    Glasstone, Samuel

    This publication is one of a series of information booklets for the general public published by The United States Atomic Energy Commission. Among the topics discussed are: Importance of Fusion Energy; Conditions for Nuclear Fusion; Thermonuclear Reactions in Plasmas; Plasma Confinement by Magnetic Fields; Experiments With Plasmas; High-Temperature…

  11. Two Horizons of Fusion

    ERIC Educational Resources Information Center

    Lo, Mun Ling; Chik, Pakey Pui Man

    2016-01-01

    In this paper, we aim to differentiate the internal and external horizons of "fusion." "Fusion" in the internal horizon relates to the structure and meaning of the object of learning as experienced by the learner. It clarifies the interrelationships among an object's critical features and aspects. It also illuminates the…

  12. EDITORIAL: Safety aspects of fusion power plants

    NASA Astrophysics Data System (ADS)

    Kolbasov, B. N.

    2007-07-01

    This special issue of Nuclear Fusion contains 13 informative papers that were initially presented at the 8th IAEA Technical Meeting on Fusion Power Plant Safety held in Vienna, Austria, 10-13 July 2006. Following recommendation from the International Fusion Research Council, the IAEA organizes Technical Meetings on Fusion Safety with the aim to bring together experts to discuss the ongoing work, share new ideas and outline general guidance and recommendations on different issues related to safety and environmental (S&E) aspects of fusion research and power facilities. Previous meetings in this series were held in Vienna, Austria (1980), Ispra, Italy (1983), Culham, UK (1986), Jackson Hole, USA (1989), Toronto, Canada (1993), Naka, Japan (1996) and Cannes, France (2000). The recognized progress in fusion research and technology over the last quarter of a century has boosted the awareness of the potential of fusion to be a practically inexhaustible and clean source of energy. The decision to construct the International Thermonuclear Experimental Reactor (ITER) represents a landmark in the path to fusion power engineering. Ongoing activities to license ITER in France look for an adequate balance between technological and scientific deliverables and complying with safety requirements. Actually, this is the first instance of licensing a representative fusion machine, and it will very likely shape the way in which a more common basis for establishing safety standards and policies for licensing future fusion power plants will be developed. Now that ITER licensing activities are underway, it is becoming clear that the international fusion community should strengthen its efforts in the area of designing the next generations of fusion power plants—demonstrational and commercial. Therefore, the 8th IAEA Technical Meeting on Fusion Safety focused on the safety aspects of power facilities. Some ITER-related safety issues were reported and discussed owing to their potential

  13. STARFIRE: a commercial tokamak fusion power plant study

    SciTech Connect

    Not Available

    1980-09-01

    This volume contains chapters on each of the following topics: (1) radioactivity, (2) heat transport and energy conversion, (3) tritium systems, (4) electrical storage and power supplies, (5) support structure, (6) cryogenics, (7) instrumentation and control, (8) maintenance and operation, (9) balance of plant design, (10) safety and environmental analysis, (11) economic analysis, and (12) plant construction.

  14. Fusion Physics Toward ITER

    NASA Astrophysics Data System (ADS)

    Stambaugh, R. D.

    2006-04-01

    Stars are powered by fusion, the energy released by fusing together light nuclei, using gravitational confinement of plasma. Fusion on earth will be done in a 100 million degree plasma made of deuterium and tritium and confined by magnetic fields or inertia. The worldwide fusion research community will construct ITER, the first experiment that will burn a DT plasma by copious fusion reactions. ITER's nominal goal is to create 500 MW of fusion power. An energy gain of 10 will mean the plasma is dominantly self-heated by the fusion-produced alpha particles. ITER's all superconducting magnet technology and steady-state heat removal technology will enable nominal 400 s pulses to allow the study of burning plasmas on the longest intrinsic timescale of the confined plasma - diffusive redistribution of the electrical currents in the plasma. The advances in magnetic confinement physics that have led to this opportunity will be described, as well as the research opportunities afforded by ITER. The physics of confining stable plasmas and heating them will produce the high gain state in ITER. Sustained burn will come from the physics of controlling currents in plasmas and how the hot plasma is interfaced to its room temperature surroundings. ITER will provide our first experience with how fusion plasma self-heating will profoundly affect the complex, interlinked physical processes that occur in confined plasmas.

  15. Fusion Studies in Japan

    NASA Astrophysics Data System (ADS)

    Ogawa, Yuichi

    2016-05-01

    A new strategic energy plan decided by the Japanese Cabinet in 2014 strongly supports the steady promotion of nuclear fusion development activities, including the ITER project and the Broader Approach activities from the long-term viewpoint. Atomic Energy Commission (AEC) in Japan formulated the Third Phase Basic Program so as to promote an experimental fusion reactor project. In 2005 AEC has reviewed this Program, and discussed on selection and concentration among many projects of fusion reactor development. In addition to the promotion of ITER project, advanced tokamak research by JT-60SA, helical plasma experiment by LHD, FIREX project in laser fusion research and fusion engineering by IFMIF were highly prioritized. Although the basic concept is quite different between tokamak, helical and laser fusion researches, there exist a lot of common features such as plasma physics on 3-D magnetic geometry, high power heat load on plasma facing component and so on. Therefore, a synergetic scenario on fusion reactor development among various plasma confinement concepts would be important.

  16. Fusion safety program Annual report, Fiscal year 1995

    SciTech Connect

    Longhurst, G.R.; Cadwallader, L.C.; Carmack, W.J.

    1995-12-01

    This report summarizes the major activities of the Fusion Safety Program in FY-95. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory, and Lockheed Idaho Technologies Company is the prime contractor for this program. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL, at other DOE laboratories, and at other institutions. Among the technical areas covered in this report are tritium safety, beryllium safety, chemical reactions and activation product release, safety aspects of fusion magnet systems, plasma disruptions, risk assessment failure rate database development, and safety code development and application to fusion safety issues. Most of this work has been done in support of the International Thermonuclear Experimental Reactor (ITER). Also included in the report are summaries of the safety and environmental studies performed by the Fusion Safety Program for the Tokamak Physics Experiment and the Tokamak Fusion Test Reactor and the technical support for commercial fusion facility conceptual design studies. A final activity described is work to develop DOE Technical Standards for Safety of Fusion Test Facilities.

  17. Fusion Safety Program annual report, fiscal year 1994

    SciTech Connect

    Longhurst, G.R.; Cadwallader, L.C.; Dolan, T.J.; Herring, J.S.; McCarthy, K.A.; Merrill, B.J.; Motloch, C.G.; Petti, D.A.

    1995-03-01

    This report summarizes the major activities of the Fusion Safety Program in fiscal year 1994. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory and Lockheed Idaho Technologies Company is the prime contractor for this program. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL, at other DOE laboratories, and at other institutions, including the University of Wisconsin. The technical areas covered in this report include tritium safety, beryllium safety, chemical reactions and activation product release, safety aspects of fusion magnet systems, plasma disruptions, risk assessment failure rate data base development, and thermalhydraulics code development and their application to fusion safety issues. Much of this work has been done in support of the International Thermonuclear Experimental Reactor (ITER). Also included in the report are summaries of the safety and environmental studies performed by the Fusion Safety Program for the Tokamak Physics Experiment and the Tokamak Fusion Test Reactor and of the technical support for commercial fusion facility conceptual design studies. A major activity this year has been work to develop a DOE Technical Standard for the safety of fusion test facilities.

  18. Spherical torus fusion reactor

    DOEpatents

    Martin Peng, Y.K.M.

    1985-10-03

    The object of this invention is to provide a compact torus fusion reactor with dramatic simplification of plasma confinement design. Another object of this invention is to provide a compact torus fusion reactor with low magnetic field and small aspect ratio stable plasma confinement. In accordance with the principles of this invention there is provided a compact toroidal-type plasma confinement fusion reactor in which only the indispensable components inboard of a tokamak type of plasma confinement region, mainly a current conducting medium which carries electrical current for producing a toroidal magnet confinement field about the toroidal plasma region, are retained.

  19. Some new inequalities for continuous fusion frames and fusion pairs.

    PubMed

    Zhang, Wei; Li, Yun-Zhang

    2016-01-01

    This paper addresses continuous fusion frames and fusion pairs which are extensions of discrete fusion frames and continuous frames. The study of equalities and inequalities for various frames has seen great achievements. In this paper, using operator methods we establish some new inequalities for continuous fusion frames and fusion pairs. Our results extend and improve ones obtained by Balan, Casazza and Găvruţa. PMID:27652173

  20. Label fusion strategy selection.

    PubMed

    Robitaille, Nicolas; Duchesne, Simon

    2012-01-01

    Label fusion is used in medical image segmentation to combine several different labels of the same entity into a single discrete label, potentially more accurate, with respect to the exact, sought segmentation, than the best input element. Using simulated data, we compared three existing label fusion techniques-STAPLE, Voting, and Shape-Based Averaging (SBA)-and observed that none could be considered superior depending on the dissimilarity between the input elements. We thus developed an empirical, hybrid technique called SVS, which selects the most appropriate technique to apply based on this dissimilarity. We evaluated the label fusion strategies on two- and three-dimensional simulated data and showed that SVS is superior to any of the three existing methods examined. On real data, we used SVS to perform fusions of 10 segmentations of the hippocampus and amygdala in 78 subjects from the ICBM dataset. SVS selected SBA in almost all cases, which was the most appropriate method overall. PMID:22518113

  1. Spinal fusion - series (image)

    MedlinePlus

    ... muscles hold the graft in place until it fuses with the vertebrae. A fusion will setup within ... hollow threaded titanium or carbon fiber cylinder to fuse two vertebrae together. The diseased disk is removed ...

  2. Magnetized Target Fusion collaboration

    NASA Astrophysics Data System (ADS)

    Intrator, Thomas

    2004-11-01

    Magnetized Target Fusion (MTF) may be a low cost path to fusion, in a regime that is intermediate between magnetic and inertial fusion energy. It requires compression of a magnetized target plasma and consequent heating to fusion relevant conditions inside a converging flux conserver. We hope to demonstrate the physics basis for MTF, with a Field Reversed Configuration (FRC) target plasma to be translated axially to a compression region. We show recent and improved FRC formation data, example deformable liner implosions, and a conceptual design for the upcoming translation experiments, and describe a multi institution collaboration. The FRC is an elongated, compact toroid equilibrium that is extreme among magnetic configurations, and relaxed to a non force free state. There is high plasma beta, small toroidal field, cross-field diamagnetic current and flows, vanishing rotational transform, magnetic shear, helicity and anomalously large resistivity. Scientific issues include MTF with and without FRC's, and fundamental plasma physics beyond MHD, relevant to geophysical and astrophysical phenomena.

  3. Cold nuclear fusion

    SciTech Connect

    Tsyganov, E. N.

    2012-02-15

    Recent accelerator experiments on fusion of various elements have clearly demonstrated that the effective cross-sections of these reactions depend on what material the target particle is placed in. In these experiments, there was a significant increase in the probability of interaction when target nuclei are imbedded in a conducting crystal or are a part of it. These experiments open a new perspective on the problem of so-called cold nuclear fusion.

  4. ITER Fusion Energy

    ScienceCinema

    Dr. Norbert Holtkamp

    2016-07-12

    ITER (in Latin “the way”) is designed to demonstrate the scientific and technological feasibility of fusion energy. Fusion is the process by which two light atomic nuclei combine to form a heavier over one and thus release energy. In the fusion process two isotopes of hydrogen – deuterium and tritium – fuse together to form a helium atom and a neutron. Thus fusion could provide large scale energy production without greenhouse effects; essentially limitless fuel would be available all over the world. The principal goals of ITER are to generate 500 megawatts of fusion power for periods of 300 to 500 seconds with a fusion power multiplication factor, Q, of at least 10. Q ? 10 (input power 50 MW / output power 500 MW). The ITER Organization was officially established in Cadarache, France, on 24 October 2007. The seven members engaged in the project – China, the European Union, India, Japan, Korea, Russia and the United States – represent more than half the world’s population. The costs for ITER are shared by the seven members. The cost for the construction will be approximately 5.5 billion Euros, a similar amount is foreseen for the twenty-year phase of operation and the subsequent decommissioning.

  5. Magnetized Target Fusion

    NASA Technical Reports Server (NTRS)

    Griffin, Steven T.

    2002-01-01

    Magnetized target fusion (MTF) is under consideration as a means of building a low mass, high specific impulse, and high thrust propulsion system for interplanetary travel. This unique combination is the result of the generation of a high temperature plasma by the nuclear fusion process. This plasma can then be deflected by magnetic fields to provide thrust. Fusion is initiated by a small traction of the energy generated in the magnetic coils due to the plasma's compression of the magnetic field. The power gain from a fusion reaction is such that inefficiencies due to thermal neutrons and coil losses can be overcome. Since the fusion reaction products are directly used for propulsion and the power to initiate the reaction is directly obtained from the thrust generation, no massive power supply for energy conversion is required. The result should be a low engine mass, high specific impulse and high thrust system. The key is to successfully initiate fusion as a proof-of-principle for this application. Currently MSFC is implementing MTF proof-of-principle experiments. This involves many technical details and ancillary investigations. Of these, selected pertinent issues include the properties, orientation and timing of the plasma guns and the convergence and interface development of the "pusher" plasma. Computer simulations of the target plasma's behavior under compression and the convergence and mixing of the gun plasma are under investigation. This work is to focus on the gun characterization and development as it relates to plasma initiation and repeatability.

  6. Parametric study of a target factory for laser fusion

    SciTech Connect

    Sherohman, J.W.; Meier, W.R.

    1980-10-08

    An analysis of a target factory leading to the derivation of production rate equations has provided the basis for a parametric study. Rate equations describing the production of laser fusion targets have been developed for the purpose of identifying key parameters, attractive production techniques and cost scaling relationships for a commercial target factory.

  7. Fusion-power demonstration. [Next step beyond MFTF-B

    SciTech Connect

    Henning, C.D.; Logan, B.G.; Carlson, G.A.; Neef, W.S.; Moir, R.W.; Campbell, R.B.; Botwin, R.; Clarkson, I.R.; Carpenter, T.J.

    1983-03-29

    As a satellite to the MARS (Mirror Advanced Reactor Study) a smaller, near-term device has been scoped, called the FPD (Fusion Power Demonstration). Envisioned as the next logical step toward a power reactor, it would advance the mirror fusion program beyond MFTF-B and provide an intermediate step toward commercial fusion power. Breakeven net electric power capability would be the goal such that no net utility power would be required to sustain the operation. A phased implementation is envisioned, with a deuterium checkout first to verify the plasma systems before significant neutron activation has occurred. Major tritium-related facilities would be installed with the second phase to produce sufficient fusion power to supply the recirculating power to maintain the neutral beams, ECRH, magnets and other auxiliary equipment.

  8. Heavy Ion Accelerator-Driven Inertial Fusion

    NASA Astrophysics Data System (ADS)

    Hofmann, Ingo

    The idea of using accelerators in the production of energy by inertial confinement fusion has been developed since the mid-1970s. The basic concept is to use accelerated beams of heavy ions to provide energy to implode and ignite a small fusion pellet. Accelerators have been seen as attractive for this application due to their reliability, high repetition rate, and potential efficiency. They are therefore competitive with high power lasers at least for the commercial production of electrical power. This review summarizes part of the development and scientific efforts directed toward this application, which has been realized over time to be an extremely demanding one. Here we focus primarily on the rf linac/storage ring driver system approach and summarize the specific development that culminated in the European HIDIF study of the late 1990s. We also discuss some of the relevant followup accelerator studies.

  9. A. Sakharov and Fusion Research

    NASA Astrophysics Data System (ADS)

    Coppi, Bruno

    2012-02-01

    In the landmark paper by Tamm and Sakharov [1], a controlled nuclear fusion reactor based on an axisymmetric magnetic confinement configuration whose principles remain valid to this day, was proposed. In the light of present understanding of plasma physics the virtues (e.g. that of considering the D-D reaction) and the shortcomings of this paper are pointed out. In fact, relatively recent results of theoretical plasma physics (e.g. discovery of the so called second stability region) and advances in high field magnet technology have made it possible to identify the parameters of meaningful experiments capable of exploring D-D and D-^3He burn conditions. At the same time an experimental program (IGNIR) has been undertaken through a (funded) collaboration between Italy and Russia to investigate D-T plasmas close to ignition conditions based on an advanced high field toroidal confinement configuration. A. Sakharov envisioned a bolder approach to fusion research than that advocated by some of his contemporaries. The time taken to design and decide to fabricate the first experiment capable of reaching ignition conditions is due in part to the problem of gaining an adequate understanding the expected physics of fusion burning plasmas. However, most of the relevant financial effort has gone in the pursuit of slow and indirect enterprises complying with the ``playing it safe'' tendencies of large organizations or motivated by the purpose to develop technologies or maintain a high level of expertise in plasma physics to the expected benefit of other kinds of endeavors. The creativity demonstrated by A. Sakharov in dealing with civil rights and disarmament issues is needed, while maintaining our concerns for energy and the environment on a global scale, to orient the funding for fusion research toward a direct and well based scientific effort on concepts for which a variety of developments can be envisioned. These can span from uncovering new physics relevant, for instance

  10. Commercial Buildings Characteristics, 1992

    SciTech Connect

    Not Available

    1994-04-29

    Commercial Buildings Characteristics 1992 presents statistics about the number, type, and size of commercial buildings in the United States as well as their energy-related characteristics. These data are collected in the Commercial Buildings Energy Consumption Survey (CBECS), a national survey of buildings in the commercial sector. The 1992 CBECS is the fifth in a series conducted since 1979 by the Energy Information Administration. Approximately 6,600 commercial buildings were surveyed, representing the characteristics and energy consumption of 4.8 million commercial buildings and 67.9 billion square feet of commercial floorspace nationwide. Overall, the amount of commercial floorspace in the United States increased an average of 2.4 percent annually between 1989 and 1992, while the number of commercial buildings increased an average of 2.0 percent annually.

  11. Fusion for Space Propulsion

    NASA Technical Reports Server (NTRS)

    Thio, Y. C. Francis; Schafer, Charles (Technical Monitor)

    2001-01-01

    There is little doubt that humans will attempt to explore and develop the solar system in this century. A large amount of energy will be required for accomplishing this. The need for fusion propulsion is discussed. For a propulsion system, there are three important thermodynamical attributes: (1) The absolute amount of energy available, (2) the propellant exhaust velocity, and (3) the jet power per unit mass of the propulsion system (specific power). For human exploration and development of the solar system, propellant exhaust velocity in excess of 100 km/s and specific power in excess of 10 kW/kg are required. Chemical combustion can produce exhaust velocity up to about 5 km/s. Nuclear fission processes typically result in producing energy in the form of heat that needs to be manipulated at temperatures limited by materials to about 2,800 K. Using the energy to heat a hydrogen propellant increases the exhaust velocity by only a factor of about two. Alternatively the energy can be converted into electricity which is then used to accelerate particles to high exhaust velocity. The necessary power conversion and conditioning equipment, however, increases the mass of the propulsion system for the same jet power by more than two orders of magnitude over chemical system, thus greatly limits the thrust-to-weight ratio attainable. The principal advantage of the fission process is that its development is relatively mature and is available right now. If fusion can be developed, fusion appears to have the best of all worlds in terms of propulsion - it can provide the absolute amount, the propellant exhaust velocity, and the high specific jet power. An intermediate step towards pure fusion propulsion is a bimodal system in which a fission reactor is used to provide some of the energy to drive a fusion propulsion unit. The technical issues related to fusion for space propulsion are discussed. The technical priorities for developing and applying fusion for propulsion are

  12. Improvements of image fusion methods

    NASA Astrophysics Data System (ADS)

    Ben-Shoshan, Yotam; Yitzhaky, Yitzhak

    2014-03-01

    Fusion of images from different imaging modalities, obtained by conventional fusion methods, may cause artifacts, including destructive superposition and brightness irregularities, in certain cases. This paper proposes two methods for improving image multimodal fusion quality. Based on the finding that a better fusion can be achieved when the images have a more positive correlation, the first method is a decision algorithm that runs at the preprocessing fusion stage and determines whether a complementary gray level of one of the input images should be used instead of the original one. The second method is suitable for multiresolution fusion, and it suggests choosing only one image from the lowest-frequency sub-bands in the pyramids, instead of combining values from both sub-bands. Experimental results indicate that the proposed fusion enhancement can reduce fusion artifacts. Quantitative fusion quality measures that support this conclusion are shown.

  13. Inertial confinement fusion reactor systems

    SciTech Connect

    Frank, T.G.; Bohachevsky, I.O.; Pendergrass, J.H.

    1980-01-01

    A variety of reactor cavity concepts, drivers, and energy conversion mechanisms are being considered to realize commercial applications of ICF. Presented in this paper are: (1) a review of reactor concepts with estimates of practically achievable pulse repetition rates; (2) a survey of drivers with estimates of the requirements on reactor conditions imposed by beam propagation characteristics; and (3) an assessment of compatible driver-reactor combinations.

  14. Commercial Spanish: Developing Proficiencies and Business Practices.

    ERIC Educational Resources Information Center

    Reyes-Tudela, Jose E.

    A commercial Spanish course offered at Marywood College (Scranton, Pennsylvania) serves both Spanish majors and majors in international business. In addition to language proficiency activities common to most commercial language courses, students have identified two projects as most functional and challenging: (1) a "carpeta" or file into which…

  15. Lateral Lumbar Interbody Fusion.

    PubMed

    Pawar, Abhijit; Hughes, Alexander; Girardi, Federico; Sama, Andrew; Lebl, Darren; Cammisa, Frank

    2015-12-01

    The lateral lumbar interbody fusion (LLIF) is a relatively new technique that allows the surgeon to access the intervertebral space from a direct lateral approach either anterior to or through the psoas muscle. This approach provides an alternative to anterior lumbar interbody fusion with instrumentation, posterior lumbar interbody fusion, and transforaminal lumbar interbody fusion for anterior column support. LLIF is minimally invasive, safe, better structural support from the apophyseal ring, potential for coronal plane deformity correction, and indirect decompression, which have has made this technique popular. LLIF is currently being utilized for a variety of pathologies including but not limited to adult de novo lumbar scoliosis, central and foraminal stenosis, spondylolisthesis, and adjacent segment degeneration. Although early clinical outcomes have been good, the potential for significant neurological and vascular vertebral endplate complications exists. Nevertheless, LLIF is a promising technique with the potential to more effectively treat complex adult de novo scoliosis and achieve predictable fusion while avoiding the complications of traditional anterior surgery and posterior interbody techniques. PMID:26713134

  16. Myoblast fusion in Drosophila

    SciTech Connect

    Haralalka, Shruti; Abmayr, Susan M.

    2010-11-01

    The body wall musculature of a Drosophila larva is composed of an intricate pattern of 30 segmentally repeated muscle fibers in each abdominal hemisegment. Each muscle fiber has unique spatial and behavioral characteristics that include its location, orientation, epidermal attachment, size and pattern of innervation. Many, if not all, of these properties are dictated by founder cells, which determine the muscle pattern and seed the fusion process. Myofibers are then derived from fusion between a specific founder cell and several fusion competent myoblasts (FCMs) fusing with as few as 3-5 FCMs in the small muscles on the most ventral side of the embryo and as many as 30 FCMs in the larger muscles on the dorsal side of the embryo. The focus of the present review is the formation of the larval muscles in the developing embryo, summarizing the major issues and players in this process. We have attempted to emphasize experimentally-validated details of the mechanism of myoblast fusion and distinguish these from the theoretically possible details that have not yet been confirmed experimentally. We also direct the interested reader to other recent reviews that discuss myoblast fusion in Drosophila, each with their own perspective on the process . With apologies, we use gene nomenclature as specified by Flybase (http://flybase.org) but provide Table 1 with alternative names and references.

  17. Lateral Lumbar Interbody Fusion

    PubMed Central

    Hughes, Alexander; Girardi, Federico; Sama, Andrew; Lebl, Darren; Cammisa, Frank

    2015-01-01

    The lateral lumbar interbody fusion (LLIF) is a relatively new technique that allows the surgeon to access the intervertebral space from a direct lateral approach either anterior to or through the psoas muscle. This approach provides an alternative to anterior lumbar interbody fusion with instrumentation, posterior lumbar interbody fusion, and transforaminal lumbar interbody fusion for anterior column support. LLIF is minimally invasive, safe, better structural support from the apophyseal ring, potential for coronal plane deformity correction, and indirect decompression, which have has made this technique popular. LLIF is currently being utilized for a variety of pathologies including but not limited to adult de novo lumbar scoliosis, central and foraminal stenosis, spondylolisthesis, and adjacent segment degeneration. Although early clinical outcomes have been good, the potential for significant neurological and vascular vertebral endplate complications exists. Nevertheless, LLIF is a promising technique with the potential to more effectively treat complex adult de novo scoliosis and achieve predictable fusion while avoiding the complications of traditional anterior surgery and posterior interbody techniques. PMID:26713134

  18. Fusion, magnetic confinement

    SciTech Connect

    Berk, H.L.

    1992-08-06

    An overview is presented of the principles of magnetic confinement of plasmas for the purpose of achieving controlled fusion conditions. Sec. 1 discusses the different nuclear fusion reactions which can be exploited in prospective fusion reactors and explains why special technologies need to be developed for the supply of tritium or {sup 3}He, the probable fuels. In Sec. 2 the Lawson condition, a criterion that is a measure of the quality of confinement relative to achieving fusion conditions, is explained. In Sec. 3 fluid equations are used to describe plasma confinement. Specific confinement configurations are considered. In Sec. 4 the orbits of particle sin magneti and electric fields are discussed. In Sec. 5 stability considerations are discussed. It is noted that confinement systems usually need to satisfy stability constraints imposed by ideal magnetohydrodynamic (MHD) theory. The paper culminates with a summary of experimental progress in magnetic confinement. Present experiments in tokamaks have reached the point that the conditions necessary to achieve fusion are being satisfied.

  19. Proliferation Risks of Fusion Energy: Clandestine Production, Covert Production, and Breakout

    SciTech Connect

    R.J. Goldston, A. Glaser, A.F. Ross

    2009-08-13

    Nuclear proliferation risks from fusion associated with access to weapon-usable material can be divided into three main categories: 1) clandestine production of fissile material in an undeclared facility, 2) covert production of such material in a declared and safeguarded facility, and 3) use of a declared facility in a breakout scenario, in which a state begins production of fissile material without concealing the effort. In this paper we address each of these categories of risk from fusion. For each case, we find that the proliferation risk from fusion systems can be much lower than the equivalent risk from fission systems, if commercial fusion systems are designed to accommodate appropriate safeguards.

  20. Peaceful Uses of Fusion

    DOE R&D Accomplishments Database

    Teller, E.

    1958-07-03

    Applications of thermonuclear energy for peaceful and constructive purposes are surveyed. Developments and problems in the release and control of fusion energy are reviewed. It is pointed out that the future of thermonuclear power reactors will depend upon the construction of a machine that produces more electric energy than it consumes. The fuel for thermonuclear reactors is cheap and practically inexhaustible. Thermonuclear reactors produce less dangerous radioactive materials than fission reactors and, when once brought under control, are not as likely to be subject to dangerous excursions. The interaction of the hot plasma with magnetic fields opens the way for the direct production of electricity. It is possible that explosive fusion energy released underground may be harnessed for the production of electricity before the same feat is accomplished in controlled fusion processes. Applications of underground detonations of fission devices in mining and for the enhancement of oil flow in large low-specific-yield formations are also suggested.

  1. Spherical torus fusion reactor

    DOEpatents

    Peng, Yueng-Kay M.

    1989-04-04

    A fusion reactor is provided having a near spherical-shaped plasma with a modest central opening through which straight segments of toroidal field coils extend that carry electrical current for generating a toroidal magnet plasma confinement fields. By retaining only the indispensable components inboard of the plasma torus, principally the cooled toroidal field conductors and in some cases a vacuum containment vessel wall, the fusion reactor features an exceptionally small aspect ratio (typically about 1.5), a naturally elongated plasma cross section without extensive field shaping, requires low strength magnetic containment fields, small size and high beta. These features combine to produce a spherical torus plasma in a unique physics regime which permits compact fusion at low field and modest cost.

  2. Spherical torus fusion reactor

    DOEpatents

    Peng, Yueng-Kay M.

    1989-01-01

    A fusion reactor is provided having a near spherical-shaped plasma with a modest central opening through which straight segments of toroidal field coils extend that carry electrical current for generating a toroidal magnet plasma confinement fields. By retaining only the indispensable components inboard of the plasma torus, principally the cooled toroidal field conductors and in some cases a vacuum containment vessel wall, the fusion reactor features an exceptionally small aspect ratio (typically about 1.5), a naturally elongated plasma cross section without extensive field shaping, requires low strength magnetic containment fields, small size and high beta. These features combine to produce a spherical torus plasma in a unique physics regime which permits compact fusion at low field and modest cost.

  3. CRYOGENICS FOR FUSION

    SciTech Connect

    Dauguet, P.; Bonneton, M.; Fauve, E.; Bernhardt, J. M.; Beauvisage, J.; Andrieu, F.; Gistau-Baguer, G. M.; Boissin, J. C.

    2008-03-16

    Fusion of Hydrogen to produce energy is one of the technologies under study to meet the mankind raising need in energy and as a substitute to fossil fuels for the future. This technology is under investigation for more than 30 years already, with, for example, the former construction of the experimental reactors Tore Supra, DIII-D and JET. With the construction of ITER to start, the next step to 'fusion for energy' will be done. In these projects, an extensive use of cryogenic systems is requested. Air Liquide has been involved as cryogenic partner in most of former and presently constructed fusion reactors. In the present paper, a review of the cryogenic systems we delivered to Tore Supra, JET, IPR and KSTAR will be presented.

  4. Fusion technology development annual report, October 1, 1995--September 30, 1996

    SciTech Connect

    1997-03-01

    In FY96, the General Atomics (GA) Fusion Group made significant contributions to the technology needs of the magnetic fusion program. The work is reported in the following sections on Fusion Power Plant Design Studies (Section 2), Plasma Interactive Materials (Section 3), SiC/SiC Composite Material Development (Section 4), Magnetic Diagnostic Probes (Section 5) and RF Technology (Section 6). Meetings attended and publications are listed in their respective sections. The overall objective of GA`s fusion technology research is to develop the technologies necessary for fusion to move successfully from present-day physics experiments to ITER and other next-generation fusion experiments, and ultimately to fusion power plants. To achieve this overall objective, the authors carry out fusion systems design studies to evaluate the technologies needed for next-step experiments and power plants, and they conduct research to develop basic knowledge about these technologies, including plasma technologies, fusion nuclear technologies, and fusion materials. They continue to be committed to the development of fusion power and its commercialization by US industry.

  5. Fusion technology development. Annual report, October 1, 1994--September 30, 1995

    SciTech Connect

    1996-08-01

    In FY95, the General Atomics (GA) Fusion Group made significant contributions to the technology needs of the magnetic fusion program. The work is reported in the following sections on Fusion Power Plant Studies (Section 2), DiMES (Section 3), SiC Composite Studies (Section 4), Magnetic Probe (Section 5) and RF Technology (Section 6). Meetings attended and publications are listed in their respective sections. The overall objective of GA`s fusion technology research is to develop the technologies necessary for fusion to move successfully from present-day physics experiments to ITER and other next-generation fusion experiments, and ultimately to fusion power plants. To achieve this overall objective, they carry out fusion systems design studies to evaluate the technologies needed for next-step experiments and power plants, and they conduct research to develop basic knowledge about these technologies, including plasma technologies, fusion nuclear technologies, and fusion materials. They continue to be committed to the development of fusion power and its commercialization by US industry.

  6. Commercialism in Experiential Education.

    ERIC Educational Resources Information Center

    Owen, Steve

    1987-01-01

    Examines perceived threat of commercialism on the ethical foundation of the experiential education movement. Contends that relationship between humanistic values often espoused by experiential educators need not be in conflict with a commercial, profit-oriented perspective. (NEC)

  7. Intense fusion neutron sources

    NASA Astrophysics Data System (ADS)

    Kuteev, B. V.; Goncharov, P. R.; Sergeev, V. Yu.; Khripunov, V. I.

    2010-04-01

    The review describes physical principles underlying efficient production of free neutrons, up-to-date possibilities and prospects of creating fission and fusion neutron sources with intensities of 1015-1021 neutrons/s, and schemes of production and application of neutrons in fusion-fission hybrid systems. The physical processes and parameters of high-temperature plasmas are considered at which optimal conditions for producing the largest number of fusion neutrons in systems with magnetic and inertial plasma confinement are achieved. The proposed plasma methods for neutron production are compared with other methods based on fusion reactions in nonplasma media, fission reactions, spallation, and muon catalysis. At present, intense neutron fluxes are mainly used in nanotechnology, biotechnology, material science, and military and fundamental research. In the near future (10-20 years), it will be possible to apply high-power neutron sources in fusion-fission hybrid systems for producing hydrogen, electric power, and technological heat, as well as for manufacturing synthetic nuclear fuel and closing the nuclear fuel cycle. Neutron sources with intensities approaching 1020 neutrons/s may radically change the structure of power industry and considerably influence the fundamental and applied science and innovation technologies. Along with utilizing the energy produced in fusion reactions, the achievement of such high neutron intensities may stimulate wide application of subcritical fast nuclear reactors controlled by neutron sources. Superpower neutron sources will allow one to solve many problems of neutron diagnostics, monitor nano-and biological objects, and carry out radiation testing and modification of volumetric properties of materials at the industrial level. Such sources will considerably (up to 100 times) improve the accuracy of neutron physics experiments and will provide a better understanding of the structure of matter, including that of the neutron itself.

  8. NASA commercial programs

    NASA Technical Reports Server (NTRS)

    1988-01-01

    An expanded role for the U.S. private sector in America's space future has emerged as a key national objective, and NASA's Office of Commercial Programs is providing a focus for action. The Office supports new high technology commercial space ventures, the commercial application of existing aeronautics and space technology, and expanded commercial access to available NASA capabilities and services. The progress NASA has made in carrying out its new assignment is highlighted.

  9. Fusion welding process

    DOEpatents

    Thomas, Kenneth C.; Jones, Eric D.; McBride, Marvin A.

    1983-01-01

    A process for the fusion welding of nickel alloy steel members wherein a ferrite containing pellet is inserted into a cavity in one member and melted by a welding torch. The resulting weld nugget, a fusion of the nickel containing alloy from the members to be welded and the pellet, has a composition which is sufficiently low in nickel content such that ferrite phases occur within the weld nugget, resulting in improved weld properties. The steel alloys encompassed also include alloys containing carbon and manganese, considered nickel equivalents.

  10. Fusion for Space Propulsion

    NASA Technical Reports Server (NTRS)

    Thio, Y. C. Francis; Schmidt, George R.; Santarius, John F.; Turchi, Peter J.; Siemon, Richard E.; Rodgers, Stephen L. (Technical Monitor)

    2002-01-01

    The need for fusion propulsion for interplanetary flights is discussed. For a propulsion system, there are three important system attributes: (1) The absolute amount of energy available, (2) the propellant exhaust velocity, and (3) the jet power per unit mass of the propulsion system (specific power). For efficient and affordable human exploration of the solar system, propellant exhaust velocity in excess of 100 km/s and specific power in excess of 10 kW/kg are required. Chemical combustion obviously cannot meet the requirement in propellant exhaust velocity. Nuclear fission processes typically result in producing energy in the form of heat that needs to be manipulated at temperatures limited by materials to about 2,800 K. Using the fission energy to heat a low atomic weight propellant produces propellant velocity of the order of 10 kinds. Alternatively the fission energy can be converted into electricity that is used to accelerate particles to high exhaust velocity. However, the necessary power conversion and conditioning equipment greatly increases the mass of the propulsion system. Fundamental considerations in waste heat rejection and power conditioning in a fission electric propulsion system place a limit on its jet specific power to the order of about 0.2 kW/kg. If fusion can be developed for propulsion, it appears to have the best of all worlds - it can provide the largest absolute amount of energy, the propellant exhaust velocity (> 100 km/s), and the high specific jet power (> 10 kW/kg). An intermediate step towards fusion propulsion might be a bimodal system in which a fission reactor is used to provide some of the energy to drive a fusion propulsion unit. There are similarities as well as differences between applying fusion to propulsion and to terrestrial electrical power generation. The similarities are the underlying plasma and fusion physics, the enabling component technologies, the computational and the diagnostics capabilities. These physics and

  11. Atomic data for fusion

    SciTech Connect

    Hunter, H.T.; Kirkpatrick, M.I.; Alvarez, I.; Cisneros, C.; Phaneuf, R.A.; Barnett, C.F.

    1990-07-01

    This report provides a handbook of recommended cross-section and rate-coefficient data for inelastic collisions between hydrogen, helium and lithium atoms, molecules and ions, and encompasses more than 400 different reactions of primary interest in fusion research. Published experimental and theoretical data have been collected and evaluated, and the recommended data are presented in tabular, graphical and parametrized form. Processes include excitation and spectral line emission, charge exchange, ionization, stripping, dissociation and particle interchange reactions. The range of collision energies is appropriate to applications in fusion-energy research.

  12. Commercial Banking Industry Survey.

    ERIC Educational Resources Information Center

    Bright Horizons Children's Centers, Cambridge, MA.

    Work and family programs are becoming increasingly important in the commercial banking industry. The objective of this survey was to collect information and prepare a commercial banking industry profile on work and family programs. Fifty-nine top American commercial banks from the Fortune 500 list were invited to participate. Twenty-two…

  13. Commercialism in Schools.

    ERIC Educational Resources Information Center

    Larson, Kirstin

    2001-01-01

    This document gives voice to concerns raised by critics and supporters of commercialism in schools and provides brief descriptions of several important resources on this topic. "Commercial Activities in School" (U.S. General Accounting Office) reports on the nature and frequency of commercial activities in public schools, as well as the laws and…

  14. COMMERCIAL FOODS, MATHEMATICS - I.

    ERIC Educational Resources Information Center

    DORNFIELD, BLANCHE E.

    THE UNDERSTANDING AND MASTERY OF FUNDAMENTAL MATHEMATICS IS A NECESSARY PART OF COMMERCIAL FOODS WORK. THIS STUDENT HANDBOOK WAS DESIGNED TO ACCOMPANY A COMMERCIAL FOODS COURSE AT THE HIGH SCHOOL LEVEL FOR STUDENTS WITH APPROPRIATE APTITUDES AND COMMERCIAL FOOD SERVICE GOALS. THE MATERIAL, TESTED IN VARIOUS INTERESTED CLASSROOMS, WAS PREPARED BY…

  15. Inertial Fusion Power Plant Concept of Operations and Maintenance

    SciTech Connect

    Anklam, T.; Knutson, B.; Dunne, A. M.; Kasper, J.; Sheehan, T.; Lang, D.; Roberts, V.; Mau, D.

    2015-01-15

    Parsons and LLNL scientists and engineers performed design and engineering work for power plant pre-conceptual designs based on the anticipated laser fusion demonstrations at the National Ignition Facility (NIF). Work included identifying concepts of operations and maintenance (O&M) and associated requirements relevant to fusion power plant systems analysis. A laser fusion power plant would incorporate a large process and power conversion facility with a laser system and fusion engine serving as the heat source, based in part on some of the systems and technologies advanced at NIF. Process operations would be similar in scope to those used in chemical, oil refinery, and nuclear waste processing facilities, while power conversion operations would be similar to those used in commercial thermal power plants. While some aspects of the tritium fuel cycle can be based on existing technologies, many aspects of a laser fusion power plant presents several important and unique O&M requirements that demand new solutions. For example, onsite recovery of tritium; unique remote material handling systems for use in areas with high radiation, radioactive materials, or high temperatures; a five-year fusion engine target chamber replacement cycle with other annual and multi-year cycles anticipated for major maintenance of other systems, structures, and components (SSC); and unique SSC for fusion target waste recycling streams. This paper describes fusion power plant O&M concepts and requirements, how O&M requirements could be met in design, and how basic organizational and planning issues can be addressed for a safe, reliable, economic, and feasible fusion power plant.

  16. Inertial fusion power plant concept of operations and maintenance

    NASA Astrophysics Data System (ADS)

    Knutson, Brad; Dunne, Mike; Kasper, Jack; Sheehan, Timothy; Lang, Dwight; Anklam, Tom; Roberts, Valerie; Mau, Derek

    2015-02-01

    Parsons and LLNL scientists and engineers performed design and engineering work for power plant pre-conceptual designs based on the anticipated laser fusion demonstrations at the National Ignition Facility (NIF). Work included identifying concepts of operations and maintenance (O&M) and associated requirements relevant to fusion power plant systems analysis. A laser fusion power plant would incorporate a large process and power conversion facility with a laser system and fusion engine serving as the heat source, based in part on some of the systems and technologies advanced at NIF. Process operations would be similar in scope to those used in chemical, oil refinery, and nuclear waste processing facilities, while power conversion operations would be similar to those used in commercial thermal power plants. While some aspects of the tritium fuel cycle can be based on existing technologies, many aspects of a laser fusion power plant presents several important and unique O&M requirements that demand new solutions. For example, onsite recovery of tritium; unique remote material handling systems for use in areas with high radiation, radioactive materials, or high temperatures; a five-year fusion engine target chamber replacement cycle with other annual and multi-year cycles anticipated for major maintenance of other systems, structures, and components (SSC); and unique SSC for fusion target waste recycling streams. This paper describes fusion power plant O&M concepts and requirements, how O&M requirements could be met in design, and how basic organizational and planning issues can be addressed for a safe, reliable, economic, and feasible fusion power plant.

  17. Fusion engineering device design description

    SciTech Connect

    Flanagan, C.A.; Steiner, D.; Smith, G.E.

    1981-12-01

    The US Magnetic Fusion Engineering Act of 1980 calls for the operation of a Fusion Engineering Device (FED) by 1990. It is the intent of the Act that the FED, in combination with other testing facilities, will establish the engineering feasibility of magnetic fusion energy. During 1981, the Fusion Engineering Design Center (FEDC), under the guidance of a Technical Management Board (TMB), developed a baseline design for the FED. This design is summarized herein.

  18. Fusion Engineering Device design description

    SciTech Connect

    Flanagan, C.A.; Steiner, D.; Smith, G.E.

    1981-12-01

    The US Magnetic Fusion Engineering Act of 1980 calls for the operation of a Fusion Engineering Device (FED) by 1990. It is the intent of the Act that the FED, in combination with other testing facilities, will establish the engineering feasibility of magnetic fusion energy. During 1981, the Fusion Engineering Design Center (FEDC), under the guidance of a Technical Management Board (TMB), developed a baseline design for the FED. This design is summarized herein.

  19. Path to Market for Compact Modular Fusion Power Cores

    NASA Astrophysics Data System (ADS)

    Woodruff, Simon; Baerny, Jennifer K.; Mattor, Nathan; Stoulil, Don; Miller, Ronald; Marston, Theodore

    2012-08-01

    The benefits of an energy source whose reactants are plentiful and whose products are benign is hard to measure, but at no time in history has this energy source been more needed. Nuclear fusion continues to promise to be this energy source. However, the path to market for fusion systems is still regularly a matter for long-term (20 + year) plans. This white paper is intended to stimulate discussion of faster commercialization paths, distilling guidance from investors, utilities, and the wider energy research community (including from ARPA-E). There is great interest in a small modular fusion system that can be developed quickly and inexpensively. A simple model shows how compact modular fusion can produce a low cost development path by optimizing traditional systems that burn deuterium and tritium, operating not only at high magnetic field strength, but also by omitting some components that allow for the core to become more compact and easier to maintain. The dominant hurdles to the development of low cost, practical fusion systems are discussed, primarily in terms of the constraints placed on the cost of development stages in the private sector. The main finding presented here is that the bridge from DOE Office of Science to the energy market can come at the Proof of Principle development stage, providing the concept is sufficiently compact and inexpensive that its development allows for a normal technology commercialization path.

  20. Human-Centered Fusion Framework

    SciTech Connect

    Posse, Christian; White, Amanda M.; Beagley, Nathaniel

    2007-05-16

    In recent years the benefits of fusing signatures extracted from large amounts of distributed and/or heterogeneous data sources have been largely documented in various problems ranging from biological protein function prediction to cyberspace monitoring. In spite of significant progress in information fusion research, there is still no formal theoretical framework for defining various types of information fusion systems, defining and analyzing relations among such types, and designing information fusion systems using a formal method approach. Consequently, fusion systems are often poorly understood, are less than optimal, and/or do not suit user needs. To start addressing these issues, we outline a formal humancentered fusion framework for reasoning about fusion strategies. Our approach relies on a new taxonomy for fusion strategies, an alternative definition of information fusion in terms of parameterized paths in signature related spaces, an algorithmic formalization of fusion strategies and a library of numeric and dynamic visual tools measuring the impact as well as the impact behavior of fusion strategies. Using a real case of intelligence analysis we demonstrate that the proposed framework enables end users to rapidly 1) develop and implement alternative fusion strategies, 2) understand the impact of each strategy, 3) compare the various strategies, and 4) perform the above steps without having to know the mathematical foundations of the framework. We also demonstrate that the human impact on a fusion system is critical in the sense that small changes in strategies do not necessarily correspond to small changes in results.

  1. A fusion of minds

    NASA Astrophysics Data System (ADS)

    Corfield, Richard

    2013-02-01

    Mystery still surrounds the visit of the astronomer Sir Bernard Lovell to the Soviet Union in 1963. But his collaboration - and that of other British scientists - eased geopolitical tensions at the height of the Cold War and paved the way for today's global ITER fusion project, as Richard Corfield explains.

  2. Bubble fusion: Preliminary estimates

    SciTech Connect

    Krakowski, R.A.

    1995-02-01

    The collapse of a gas-filled bubble in disequilibrium (i.e., internal pressure {much_lt} external pressure) can occur with a significant focusing of energy onto the entrapped gas in the form of pressure-volume work and/or acoustical shocks; the resulting heating can be sufficient to cause ionization and the emission of atomic radiations. The suggestion that extreme conditions necessary for thermonuclear fusion to occur may be possible has been examined parametrically in terms of the ratio of initial bubble pressure relative to that required for equilibrium. In this sense, the disequilibrium bubble is viewed as a three-dimensional ``sling shot`` that is ``loaded`` to an extent allowed by the maximum level of disequilibrium that can stably be achieved. Values of this disequilibrium ratio in the range 10{sup {minus}5}--10{sup {minus}6} are predicted by an idealized bubble-dynamics model as necessary to achieve conditions where nuclear fusion of deuterium-tritium might be observed. Harmonic and aharmonic pressurizations/decompressions are examined as means to achieve the required levels of disequilibrium required to create fusion conditions. A number of phenomena not included in the analysis reported herein could enhance or reduce the small levels of nuclear fusions predicted.

  3. Mars manned fusion spaceship

    SciTech Connect

    Hedrick, J.; Buchholtz, B.; Ward, P.; Freuh, J.; Jensen, E.

    1991-01-01

    Fusion Propulsion has an enormous potential for space exploration in the near future. In the twenty-first century, a usable and efficient fusion rocket will be developed and in use. Because of the great distance between other planets and Earth, efficient use of time, fuel, and payload is essential. A nuclear spaceship would provide greater fuel efficiency, less travel time, and a larger payload. Extended missions would give more time for research, experiments, and data acquisition. With the extended mission time, a need for an artificial environment exists. The topics of magnetic fusion propulsion, living modules, artificial gravity, mass distribution, space connection, and orbital transfer to Mars are discussed. The propulsion system is a magnetic fusion reactor based on a tandem mirror design. This allows a faster, shorter trip time and a large thrust to weight ratio. The fuel proposed is a mixture of deuterium and helium. Helium can be obtained from lunar mining. There will be minimal external radiation from the reactor resulting in a safe, efficient propulsion system.

  4. Multilevel fusion exploitation

    NASA Astrophysics Data System (ADS)

    Lindberg, Perry C.; Dasarathy, Belur V.; McCullough, Claire L.

    1996-06-01

    This paper describes a project that was sponsored by the U.S. Army Space and Strategic Defense Command (USASSDC) to develop, test, and demonstrate sensor fusion algorithms for target recognition. The purpose of the project was to exploit the use of sensor fusion at all levels (signal, feature, and decision levels) and all combinations to improve target recognition capability against tactical ballistic missile (TBM) targets. These algorithms were trained with simulated radar signatures to accurately recognize selected TBM targets. The simulated signatures represent measurements made by two radars (S-band and X- band) with the targets at a variety of aspect and roll angles. Two tests were conducted: one with simulated signatures collected at angles different from those in the training database and one using actual test data. The test results demonstrate a high degree of recognition accuracy. This paper describes the training and testing techniques used; shows the fusion strategy employed; and illustrates the advantages of exploiting multi-level fusion.

  5. Mars manned fusion spaceship

    NASA Technical Reports Server (NTRS)

    Hedrick, James; Buchholtz, Brent; Ward, Paul; Freuh, Jim; Jensen, Eric

    1991-01-01

    Fusion Propulsion has an enormous potential for space exploration in the near future. In the twenty-first century, a usable and efficient fusion rocket will be developed and in use. Because of the great distance between other planets and Earth, efficient use of time, fuel, and payload is essential. A nuclear spaceship would provide greater fuel efficiency, less travel time, and a larger payload. Extended missions would give more time for research, experiments, and data acquisition. With the extended mission time, a need for an artificial environment exists. The topics of magnetic fusion propulsion, living modules, artificial gravity, mass distribution, space connection, and orbital transfer to Mars are discussed. The propulsion system is a magnetic fusion reactor based on a tandem mirror design. This allows a faster, shorter trip time and a large thrust to weight ratio. The fuel proposed is a mixture of deuterium and helium-3. Helium-3 can be obtained from lunar mining. There will be minimal external radiation from the reactor resulting in a safe, efficient propulsion system.

  6. Fusion reactor materials

    SciTech Connect

    none,

    1989-01-01

    This paper discuses the following topics on fusion reactor materials: irradiation, facilities, test matrices, and experimental methods; dosimetry, damage parameters, and activation calculations; materials engineering and design requirements; fundamental mechanical behavior; radiation effects; development of structural alloys; solid breeding materials; and ceramics.

  7. NASA's commercial space program

    NASA Technical Reports Server (NTRS)

    Ott, Richard H.

    1992-01-01

    This paper will review the goals, status and progress of NASA's commercial space development program administered by the Office of Commercial Programs (OCP). The technologies and flight programs underway by NASA's Centers for Commercial Development (CCDS), NASA's field centers, and the NASA/Industry Joint Endeavor Programs will be summarized. A summary of completed and upcoming commercial payload activities on Shuttle, suborbital rockets, and orbital ELV's will be provided. The new commercial infrastructure and transportation initiatives will be discussed including the Wake Shield Facility, Consort and Joust suborbital rocket programs, the COMET orbital and recovery program, and the Commercial Middeck Accommodation Module Program with Spacehab Inc. Finally, the Commercial Space Station Freedom Program planned by OCP will be reviewed.

  8. Concepts and designs of D-T fusion electricity generating plant

    NASA Astrophysics Data System (ADS)

    Hancox, R.

    1981-04-01

    It is noted that although the plasma temperature and confinement time required for a fusion reactor have not yet been simultaneously obtained in laboratory experiments, the progress made thus far in fusion research encourages the expectation that they will be achieved during the coming decade. It is therefore now considered desirable to develop conceptual designs of deuterium-tritium fuelled commercial fusion reactors for the generation of electricity. The additional physical and technological developments required for the construction of fusion reactors are surveyed, and two conceptual designs are described. It is noted that on the basis of such designs the anticipated advantages and costs of fusion can be assessed and possible time-scales for the development of fusion power can be proposed.

  9. Method for selecting hollow microspheres for use in laser fusion targets

    DOEpatents

    Farnum, Eugene H.; Fries, R. Jay; Havenhill, Jerry W.; Smith, Maurice Lee; Stoltz, Daniel L.

    1976-01-01

    Hollow microspheres having thin and very uniform wall thickness are useful as containers for the deuterium and tritium gas mixture used as a fuel in laser fusion targets. Hollow microspheres are commercially available; however, in commercial lots only a very small number meet the rigid requirements for use in laser fusion targets. Those meeting these requirements may be separated from the unsuitable ones by subjecting the commercial lot to size and density separations and then by subjecting those hollow microspheres thus separated to an external pressurization at which those which are aspherical or which have nonuniform walls are broken and separating the sound hollow microspheres from the broken ones.

  10. Overview of the Lockheed Martin Compact Fusion Reactor (CFR) Program

    NASA Astrophysics Data System (ADS)

    McGuire, Thomas

    2015-11-01

    The Lockheed Martin Compact Fusion Reactor (CFR) Program endeavors to quickly develop a compact fusion power plant with favorable commercial economics and military utility. An overview of the concept and its diamagnetic, high beta magnetically encapsulated linear ring cusp confinement scheme will be given. The analytical model of the major loss mechanisms and predicted performance will be discussed, along with the major physics challenges. Key features of an operational CFR reactor will be highlighted. The proposed developmental path following the current experimental efforts will be presented. ©2015 Lockheed Martin Corporation. All Rights Reserved.

  11. Fusion-Fission Burner for Transuranic Actinides

    NASA Astrophysics Data System (ADS)

    Choi, Chan

    2013-10-01

    The 14-MeV DT fusion neutron spectrum from mirror confinement fusion can provide a unique capability to transmute the transuranic isotopes from light water reactors (LWR). The transuranic (TRU) actinides, high-level radioactive wastes, from spent LWR fuel pose serious worldwide problem with long-term decay heat and radiotoxicity. However, ``transmuted'' TRU actinides can not only reduce the inventory of the TRU in the spent fuel repository but also generate additional energy. Typical commercial LWR fuel assemblies for BWR (boiling water reactor) and PWR (pressurized water reactor) measure its assembly lengths with 4.470 m and 4.059 m, respectively, while its corresponding fuel rod lengths are 4.064 m and 3.851 m. Mirror-based fusion reactor has inherently simple geometry for transmutation blanket with steady-state reactor operation. Recent development of gas-dynamic mirror configuration has additional attractive feature with reduced size in central plasma chamber, thus providing a unique capability for incorporating the spent fuel assemblies into transmutation blanket designs. The system parameters for the gas-dynamic mirror-based hybrid burner will be discussed.

  12. World commercial aircraft accidents

    SciTech Connect

    Kimura, C.Y.

    1993-01-01

    This report is a compilation of all accidents world-wide involving aircraft in commercial service which resulted in the loss of the airframe or one or more fatality, or both. This information has been gathered in order to present a complete inventory of commercial aircraft accidents. Events involving military action, sabotage, terrorist bombings, hijackings, suicides, and industrial ground accidents are included within this list. Included are: accidents involving world commercial jet aircraft, world commercial turboprop aircraft, world commercial pistonprop aircraft with four or more engines and world commercial pistonprop aircraft with two or three engines from 1946 to 1992. Each accident is presented with information in the following categories: date of the accident, airline and its flight numbers, type of flight, type of aircraft, aircraft registration number, construction number/manufacturers serial number, aircraft damage, accident flight phase, accident location, number of fatalities, number of occupants, cause, remarks, or description (brief) of the accident, and finally references used. The sixth chapter presents a summary of the world commercial aircraft accidents by major aircraft class (e.g. jet, turboprop, and pistonprop) and by flight phase. The seventh chapter presents several special studies including a list of world commercial aircraft accidents for all aircraft types with 100 or more fatalities in order of decreasing number of fatalities, a list of collision accidents involving commercial aircrafts, and a list of world commercial aircraft accidents for all aircraft types involving military action, sabotage, terrorist bombings, and hijackings.

  13. Enhanced image capture through fusion

    NASA Technical Reports Server (NTRS)

    Burt, Peter J.; Hanna, Keith; Kolczynski, Raymond J.

    1993-01-01

    Image fusion may be used to combine images from different sensors, such as IR and visible cameras, to obtain a single composite with extended information content. Fusion may also be used to combine multiple images from a given sensor to form a composite image in which information of interest is enhanced. We present a general method for performing image fusion and show that this method is effective for diverse fusion applications. We suggest that fusion may provide a powerful tool for enhanced image capture with broad utility in image processing and computer vision.

  14. Segment fusion of ToF-SIMS images.

    PubMed

    Milillo, Tammy M; Miller, Mary E; Fischione, Remo; Montes, Angelina; Gardella, Joseph A

    2016-06-08

    The imaging capabilities of time-of-flight secondary ion mass spectrometry (ToF-SIMS) have not been used to their full potential in the analysis of polymer and biological samples. Imaging has been limited by the size of the dataset and the chemical complexity of the sample being imaged. Pixel and segment based image fusion algorithms commonly used in remote sensing, ecology, geography, and geology provide a way to improve spatial resolution and classification of biological images. In this study, a sample of Arabidopsis thaliana was treated with silver nanoparticles and imaged with ToF-SIMS. These images provide insight into the uptake mechanism for the silver nanoparticles into the plant tissue, giving new understanding to the mechanism of uptake of heavy metals in the environment. The Munechika algorithm was programmed in-house and applied to achieve pixel based fusion, which improved the spatial resolution of the image obtained. Multispectral and quadtree segment or region based fusion algorithms were performed using ecognition software, a commercially available remote sensing software suite, and used to classify the images. The Munechika fusion improved the spatial resolution for the images containing silver nanoparticles, while the segment fusion allowed classification and fusion based on the tissue types in the sample, suggesting potential pathways for the uptake of the silver nanoparticles.

  15. Segment fusion of ToF-SIMS images.

    PubMed

    Milillo, Tammy M; Miller, Mary E; Fischione, Remo; Montes, Angelina; Gardella, Joseph A

    2016-06-01

    The imaging capabilities of time-of-flight secondary ion mass spectrometry (ToF-SIMS) have not been used to their full potential in the analysis of polymer and biological samples. Imaging has been limited by the size of the dataset and the chemical complexity of the sample being imaged. Pixel and segment based image fusion algorithms commonly used in remote sensing, ecology, geography, and geology provide a way to improve spatial resolution and classification of biological images. In this study, a sample of Arabidopsis thaliana was treated with silver nanoparticles and imaged with ToF-SIMS. These images provide insight into the uptake mechanism for the silver nanoparticles into the plant tissue, giving new understanding to the mechanism of uptake of heavy metals in the environment. The Munechika algorithm was programmed in-house and applied to achieve pixel based fusion, which improved the spatial resolution of the image obtained. Multispectral and quadtree segment or region based fusion algorithms were performed using ecognition software, a commercially available remote sensing software suite, and used to classify the images. The Munechika fusion improved the spatial resolution for the images containing silver nanoparticles, while the segment fusion allowed classification and fusion based on the tissue types in the sample, suggesting potential pathways for the uptake of the silver nanoparticles. PMID:26746167

  16. The Need for Fusion Propulsion

    NASA Technical Reports Server (NTRS)

    Cassibry, Jason

    2005-01-01

    Fusion propulsion is inevitable if the human race remains dedicated to exploration of the solar system. There are fundamental reasons why fusion surpasses more traditional approaches to routine crewed missions to Mars, crewed missions to the outer planets, and deep space high speed robotic missions, assuming that reduced trip times, increased payloads, and higher available power are desired. A recent series of informal discussions were held among members from government, academia, and industry concerning fusion propulsion. We compiled a sufficient set of arguments for utilizing fusion in space. If the U.S. is to lead the effort and produce a working system in a reasonable amount of time, NASA must take the initiative, relying on, but not waiting for, DOE guidance. In this talk those arguments for fusion propulsion are presented, along with fusion enabled mission examples, fusion technology trade space, and a proposed outline for future efforts.

  17. Lunar Commercialization Workshop

    NASA Technical Reports Server (NTRS)

    Martin, Gary L.

    2008-01-01

    This slide presentation describes the goals and rules of the workshop on Lunar Commercialization. The goal of the workshop is to explore the viability of using public-private partnerships to open the new space frontier. The bulk of the workshop was a team competition to create a innovative business plan for the commercialization of the moon. The public private partnership concept is reviewed, and the open architecture as an infrastructure for potential external cooperation. Some possible lunar commercialization elements are reviewed.

  18. Methodology for Scaling Fusion Power Plant Availability

    SciTech Connect

    Lester M. Waganer

    2011-01-04

    Normally in the U.S. fusion power plant conceptual design studies, the development of the plant availability and the plant capital and operating costs makes the implicit assumption that the plant is a 10th of a kind fusion power plant. This is in keeping with the DOE guidelines published in the 1970s, the PNL report1, "Fusion Reactor Design Studies - Standard Accounts for Cost Estimates. This assumption specifically defines the level of the industry and technology maturity and eliminates the need to define the necessary research and development efforts and costs to construct a one of a kind or the first of a kind power plant. It also assumes all the "teething" problems have been solved and the plant can operate in the manner intended. The plant availability analysis assumes all maintenance actions have been refined and optimized by the operation of the prior nine or so plants. The actions are defined to be as quick and efficient as possible. This study will present a methodology to enable estimation of the availability of the one of a kind (one OAK) plant or first of a kind (1st OAK) plant. To clarify, one of the OAK facilities might be the pilot plant or the demo plant that is prototypical of the next generation power plant, but it is not a full-scale fusion power plant with all fully validated "mature" subsystems. The first OAK facility is truly the first commercial plant of a common design that represents the next generation plant design. However, its subsystems, maintenance equipment and procedures will continue to be refined to achieve the goals for the 10th OAK power plant.

  19. An accelerated fusion power development plan

    NASA Astrophysics Data System (ADS)

    Dean, Stephen O.; Baker, Charles C.; Cohn, Daniel R.; Kinkead, Susan D.

    1991-06-01

    Energy for electricity and transportation is a national issue with worldwide environmental and political implications. The world must have energy options for the next century that are not vulnerable to possible disruption for technical, environmental, public confidence, or other reasons. Growing concerns about the greenhouse effect and the safety of transporting oil may lead to reduced burning of coal and other fossil fuels, and the incidents at Three Mile Island and Chernobyl, as well as nuclear waste storage problems, have eroded public acceptance of nuclear fission. Meeting future world energy needs will require improvements in energy efficiency and conservation. However, the world will soon need new central station power plants and increasing amounts of fuel for the transportation sector. The use of fossil fuels, and possibly even fission power, will very likely be restricted because of environmental, safety, and, eventually, supply considerations. Time is running out for policymakers. New energy technologies cannot be brought to the marketplace overnight. Decades are required to bring a new energy production technology from conception to full market penetration. With the added urgency to mitigate deleterious environmental effects of energy use, policymakers must act decisively now to establish and support vigorous energy technology development programs. The U.S. has invested 8 billion over the past 40 years in fusion research and development. If the U.S. fusion program proceeds according to its present strategy, an additional 40 years, and more money, will be expended before fusion will provide commercial electricity. Such an extended schedule is neither cost-effective nor technically necessary. It is time to launch a national venture to construct and operate a fusion power pilot plant. Such a plant could be operational within 15 years of a national commitment to proceed.

  20. Unconventional approaches to fusion

    SciTech Connect

    Brunelli, B.; Leotta, G.G.

    1982-01-01

    This volume is dedicated to unconventional approaches to fusionthose thermonuclear reactors that, in comparison with Tokamak and other main lines, have received little attention in the worldwide scientific community. Many of the approaches considered are still in the embryonic stages. The authors-an international group of active nuclear scientists and engineers-focus on the parameters achieved in the use of these reactors and on the meaning of the most recent physical studies and their implications for the future. They also compare these approaches with conventional ones, the Tokamak in particular, stressing the non-plasma-physics requirements of fusion reactors. Unconventional compact toroids, linear systems, and multipoles are considered, as are the ''almost conventional'' fusion machines: stellarators, mirrors, reversed-field pinches, and EBT.

  1. Fusion Data Grid Service

    NASA Astrophysics Data System (ADS)

    Shasharina, Svetlana; Wang, Nanbor

    2004-11-01

    Simulations and experiments in the fusion and plasma physics community generate large datasets at remote sites. Visualization and analysis of these datasets are difficult because of the incompatibility among the various data formats adopted by simulation, experiments, and analysis tools, and the large sizes of analyzed data. Grids and Web Services technologies are capable of providing solutions for such heterogeneous settings, but need to be customized to the field-specific needs and merged with distributed technologies currently used by the community. This paper describes how we are addressing these issues in the Fusion Grid Service under development. We also present performance results of relevant data transfer mechanisms including binary SOAP, DIME, GridFTP and MDSplus and CORBA. We will describe the status of data converters (between HDF5 and MDSplus data types), developed in collaboration with MIT (J. Stillerman). Finally, we will analyze bottlenecks of MDSplus data transfer mechanism (work performed in collaboration with General Atomics (D. Schissel and M. Qian).

  2. Fusion pumped laser

    DOEpatents

    Pappas, D.S.

    1987-07-31

    The apparatus of this invention may comprise a system for generating laser radiation from a high-energy neutron source. The neutron source is a tokamak fusion reactor generating a long pulse of high-energy neutrons and having a temperature and magnetic field effective to generate a neutron flux of at least 10/sup 15/ neutrons/cm/sup 2//center dot/s. Conversion means are provided adjacent the fusion reactor at a location operable for converting the high-energy neutrons to an energy source with an intensity and energy effective to excite a preselected lasing medium. A lasing medium is spaced about and responsive to the energy source to generate a population inversion effective to support laser oscillations for generating output radiation. 2 figs., 2 tabs.

  3. Experiments in cold fusion

    SciTech Connect

    Palmer, E.P.

    1986-03-28

    The work of Steve Jones and others in muon-catalyzed cold fusion of deuterium and hydrogen suggests the possibility of such fusion catalyzed by ions, or combinations of atoms, or more-or-less free electrons in solid and liquid materials. A hint that this might occur naturally comes from the heat generated in volcanic action in subduction zones on the earth. It is questionable whether the potential energy of material raised to the height of a midocean ridge and falling to the depth of an ocean trench can produce the geothermal effects seen in the volcanoes of subduction zones. If the ridge, the trench, the plates, and the asthenosphere are merely visible effects of deeper density-gradient driven circulations, it is still uncertain that observed energy-concentration effects fit the models.

  4. Modular Aneutronic Fusion Engine

    SciTech Connect

    Gary Pajer, Yosef Razin, Michael Paluszek, A.H. Glasser and Samuel Cohen

    2012-05-11

    NASA's JUNO mission will arrive at Jupiter in July 2016, after nearly five years in space. Since operational costs tend to rise with mission time, minimizing such times becomes a top priority. We present the conceptual design for a 10MW aneutronic fusion engine with high exhaust velocities that would reduce transit time for a Jupiter mission to eighteen months and enable more challenging exploration missions in the solar system and beyond. __________________________________________________

  5. Inertial Confinement fusion targets

    NASA Technical Reports Server (NTRS)

    Hendricks, C. D.

    1982-01-01

    Inertial confinement fusion (ICF) targets are made as simple flat discs, as hollow shells or as complicated multilayer structures. Many techniques were devised for producing the targets. Glass and metal shells are made by using drop and bubble techniques. Solid hydrogen shells are also produced by adapting old methods to the solution of modern problems. Some of these techniques, problems, and solutions are discussed. In addition, the applications of many of the techniques to fabrication of ICF targets is presented.

  6. (Fusion energy research)

    SciTech Connect

    Phillips, C.A.

    1988-01-01

    This report discusses the following topics: principal parameters achieved in experimental devices (FY88); tokamak fusion test reactor; Princeton beta Experiment-Modification; S-1 Spheromak; current drive experiment; x-ray laser studies; spacecraft glow experiment; plasma deposition and etching of thin films; theoretical plasma; tokamak modeling; compact ignition tokamak; international thermonuclear experimental reactor; Engineering Department; Project Planning and Safety Office; quality assurance and reliability; and technology transfer.

  7. Cold fusion studies

    NASA Astrophysics Data System (ADS)

    Hembree, D. M.; Burchfield, L. A.; Fuller, E. L., Jr.; Perey, F. G.; Mamantov, G.

    1990-06-01

    A series of experiments designed to detect the by-products expected from deuterium fusion occurring in the palladium and titanium cathodes of heavy water, D2O, electrolysis cells is reported. The primary purpose of this account is to outline the integrated experimental design developed to test the cold fusion hypothesis and to report preliminary results that support continuing the investigation. Apparent positive indicators of deuterium fusion were observed, but could not be repeated or proved to originate from the electrochemical cells. In one instance, two large increases in the neutron count rate, the largest of which exceeded the background by 27 standard deviations, were observed. In a separate experiment, one of the calorimetry cells appeared to be producing approximately 18 percent more power that the input value, but thermistor failure prevented an accurate recording of the event as a function of time. In general, the tritium levels in most cells followed the slow enrichment expected from the electrolysis of D2O containing a small amount of tritium. However, after 576 hours of electrolysis, one cell developed a tritium concentration approximately seven times greater than expected level.

  8. Multimodality Image Fusion-Guided Procedures: Technique, Accuracy, and Applications

    SciTech Connect

    Abi-Jaoudeh, Nadine; Kruecker, Jochen; Kadoury, Samuel; Kobeiter, Hicham; Venkatesan, Aradhana M. Levy, Elliot Wood, Bradford J.

    2012-10-15

    Personalized therapies play an increasingly critical role in cancer care: Image guidance with multimodality image fusion facilitates the targeting of specific tissue for tissue characterization and plays a role in drug discovery and optimization of tailored therapies. Positron-emission tomography (PET), magnetic resonance imaging (MRI), and contrast-enhanced computed tomography (CT) may offer additional information not otherwise available to the operator during minimally invasive image-guided procedures, such as biopsy and ablation. With use of multimodality image fusion for image-guided interventions, navigation with advanced modalities does not require the physical presence of the PET, MRI, or CT imaging system. Several commercially available methods of image-fusion and device navigation are reviewed along with an explanation of common tracking hardware and software. An overview of current clinical applications for multimodality navigation is provided.

  9. Sensor fusion for synthetic vision

    NASA Technical Reports Server (NTRS)

    Pavel, M.; Larimer, J.; Ahumada, A.

    1991-01-01

    Display methodologies are explored for fusing images gathered by millimeter wave sensors with images rendered from an on-board terrain data base to facilitate visually guided flight and ground operations in low visibility conditions. An approach to fusion based on multiresolution image representation and processing is described which facilitates fusion of images differing in resolution within and between images. To investigate possible fusion methods, a workstation-based simulation environment is being developed.

  10. Inertial fusion research in China

    NASA Astrophysics Data System (ADS)

    He, X. T.; Zhang, W. Y.

    2007-08-01

    The goal of the first milestone of the inertial fusion program in China is to reach fusion ignition and plasma burning in about 2020. Under the program, in the past years, the inertial fusion physics research achieved great progress; the laser facilities and the support technologies for laser drivers are advanced; the advanced diagnostic techniques are developed and the relatively integrated system is set up; the precise target fabrications are coordinately developed.

  11. EDITORIAL: The Nuclear Fusion Award The Nuclear Fusion Award

    NASA Astrophysics Data System (ADS)

    Kikuchi, M.

    2011-01-01

    The Nuclear Fusion Award ceremony for 2009 and 2010 award winners was held during the 23rd IAEA Fusion Energy Conference in Daejeon. This time, both 2009 and 2010 award winners were celebrated by the IAEA and the participants of the 23rd IAEA Fusion Energy Conference. The Nuclear Fusion Award is a paper prize to acknowledge the best distinguished paper among the published papers in a particular volume of the Nuclear Fusion journal. Among the top-cited and highly-recommended papers chosen by the Editorial Board, excluding overview and review papers, and by analyzing self-citation and non-self-citation with an emphasis on non-self-citation, the Editorial Board confidentially selects ten distinguished papers as nominees for the Nuclear Fusion Award. Certificates are given to the leading authors of the Nuclear Fusion Award nominees. The final winner is selected among the ten nominees by the Nuclear Fusion Editorial Board voting confidentially. 2009 Nuclear Fusion Award nominees For the 2009 award, the papers published in the 2006 volume were assessed and the following papers were nominated, most of which are magnetic confinement experiments, theory and modeling, while one addresses inertial confinement. Sabbagh S.A. et al 2006 Resistive wall stabilized operation in rotating high beta NSTX plasmas Nucl. Fusion 46 635-44 La Haye R.J. et al 2006 Cross-machine benchmarking for ITER of neoclassical tearing mode stabilization by electron cyclotron current drive Nucl. Fusion 46 451-61 Honrubia J.J. et al 2006 Three-dimensional fast electron transport for ignition-scale inertial fusion capsules Nucl. Fusion 46 L25-8 Ido T. et al 2006 Observation of the interaction between the geodesic acoustic mode and ambient fluctuation in the JFT-2M tokamak Nucl. Fusion 46 512-20 Plyusnin V.V. et al 2006 Study of runaway electron generation during major disruptions in JET Nucl. Fusion 46 277-84 Pitts R.A. et al 2006 Far SOL ELM ion energies in JET Nucl. Fusion 46 82-98 Berk H.L. et al 2006

  12. High Level Information Fusion (HLIF) with nested fusion loops

    NASA Astrophysics Data System (ADS)

    Woodley, Robert; Gosnell, Michael; Fischer, Amber

    2013-05-01

    Situation modeling and threat prediction require higher levels of data fusion in order to provide actionable information. Beyond the sensor data and sources the analyst has access to, the use of out-sourced and re-sourced data is becoming common. Through the years, some common frameworks have emerged for dealing with information fusion—perhaps the most ubiquitous being the JDL Data Fusion Group and their initial 4-level data fusion model. Since these initial developments, numerous models of information fusion have emerged, hoping to better capture the human-centric process of data analyses within a machine-centric framework. 21st Century Systems, Inc. has developed Fusion with Uncertainty Reasoning using Nested Assessment Characterizer Elements (FURNACE) to address challenges of high level information fusion and handle bias, ambiguity, and uncertainty (BAU) for Situation Modeling, Threat Modeling, and Threat Prediction. It combines JDL fusion levels with nested fusion loops and state-of-the-art data reasoning. Initial research has shown that FURNACE is able to reduce BAU and improve the fusion process by allowing high level information fusion (HLIF) to affect lower levels without the double counting of information or other biasing issues. The initial FURNACE project was focused on the underlying algorithms to produce a fusion system able to handle BAU and repurposed data in a cohesive manner. FURNACE supports analyst's efforts to develop situation models, threat models, and threat predictions to increase situational awareness of the battlespace. FURNACE will not only revolutionize the military intelligence realm, but also benefit the larger homeland defense, law enforcement, and business intelligence markets.

  13. OCULUS Sea Track Fusion Service

    NASA Astrophysics Data System (ADS)

    Panagiotou, Stylianos C.; Rizogiannis, Constantinos; Katsoulis, Stavros; Lampropoulos, Vassilis; Kanellopoulos, Sotirios; Thomopoulos, Stelios C. A.

    2015-06-01

    Oculus Sea is a complete solution regarding maritime surveillance and communications at Local as well as Central Command and Control level. It includes a robust and independent track fusion service whose main functions include: 1) Interaction with the User to suggest the fusion of two or more tracks, confirm Track ID and Vessel Metadata creation for the fused track, and suggest de-association of two tracks 2) Fusion of same vessel tracks arriving simultaneously from multiple radar sensors featuring track Association, track Fusion of associated tracks to produce a more accurate track, and Multiple tracking filters and fusion algorithms 3) Unique Track ID Generator for each fused track 4) Track Dissemination Service. Oculus Sea Track Fusion Service adopts a system architecture where each sensor is associated with a Kalman estimator/tracker that obtains an estimate of the state vector and its respective error covariance matrix. Finally, at the fusion center, association and track state estimation fusion are carried out. The expected benefits of this system include multi-sensor information fusion, enhanced spatial resolution, and improved target detection.

  14. Coresident sensor fusion and compression using the wavelet transform

    SciTech Connect

    Yocky, D.A.

    1996-03-11

    Imagery from coresident sensor platforms, such as unmanned aerial vehicles, can be combined using, multiresolution decomposition of the sensor images by means of the two-dimensional wavelet transform. The wavelet approach uses the combination of spatial/spectral information at multiple scales to create a fused image. This can be done in both an ad hoc or model-based approach. We compare results from commercial ``fusion`` software and the ad hoc, wavelet approach. Results show the wavelet approach outperforms the commercial algorithms and also supports efficient compression of the fused image.

  15. Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.

    PubMed

    Giacomini, Craig P; Sun, Steven; Varma, Sushama; Shain, A Hunter; Giacomini, Marilyn M; Balagtas, Jay; Sweeney, Robert T; Lai, Everett; Del Vecchio, Catherine A; Forster, Andrew D; Clarke, Nicole; Montgomery, Kelli D; Zhu, Shirley; Wong, Albert J; van de Rijn, Matt; West, Robert B; Pollack, Jonathan R

    2013-04-01

    Gene fusions, like BCR/ABL1 in chronic myelogenous leukemia, have long been recognized in hematologic and mesenchymal malignancies. The recent finding of gene fusions in prostate and lung cancers has motivated the search for pathogenic gene fusions in other malignancies. Here, we developed a "breakpoint analysis" pipeline to discover candidate gene fusions by tell-tale transcript level or genomic DNA copy number transitions occurring within genes. Mining data from 974 diverse cancer samples, we identified 198 candidate fusions involving annotated cancer genes. From these, we validated and further characterized novel gene fusions involving ROS1 tyrosine kinase in angiosarcoma (CEP85L/ROS1), SLC1A2 glutamate transporter in colon cancer (APIP/SLC1A2), RAF1 kinase in pancreatic cancer (ATG7/RAF1) and anaplastic astrocytoma (BCL6/RAF1), EWSR1 in melanoma (EWSR1/CREM), CDK6 kinase in T-cell acute lymphoblastic leukemia (FAM133B/CDK6), and CLTC in breast cancer (CLTC/VMP1). Notably, while these fusions involved known cancer genes, all occurred with novel fusion partners and in previously unreported cancer types. Moreover, several constituted druggable targets (including kinases), with therapeutic implications for their respective malignancies. Lastly, breakpoint analysis identified new cell line models for known rearrangements, including EGFRvIII and FIP1L1/PDGFRA. Taken together, we provide a robust approach for gene fusion discovery, and our results highlight a more widespread role of fusion genes in cancer pathogenesis. PMID:23637631

  16. Cold nuclear fusion

    NASA Astrophysics Data System (ADS)

    Tsyganov, E. N.; Bavizhev, M. D.; Buryakov, M. G.; Dabagov, S. B.; Golovatyuk, V. M.; Lobastov, S. P.

    2015-07-01

    If target deuterium atoms were implanted in a metal crystal in accelerator experiments, a sharp increase in the probability of DD-fusion reaction was clearly observed when compared with the reaction's theoretical value. The electronic screening potential, which for a collision of free deuterium atoms is about 27 eV, reached 300-700 eV in the case of the DD-fusion in metallic crystals. These data leads to the conclusion that a ban must exist for deuterium atoms to be in the ground state 1s in a niche filled with free conduction electrons. At the same time, the state 2p whose energy level is only 10 eV above that of state 1s is allowed in these conditions. With anisotropy of 2p, 3p or above orbitals, their spatial positions are strictly determined in the lattice coordinate system. When filling out the same potential niches with two deuterium atoms in the states 2p, 3p or higher, the nuclei of these atoms can be permanently positioned without creating much Coulomb repulsion at a very short distance from each other. In this case, the transparency of the potential barrier increases dramatically compared to the ground state 1s for these atoms. The probability of the deuterium nuclei penetrating the Coulomb barrier by zero quantum vibration of the DD-system also increases dramatically. The so-called cold nuclear DD-fusion for a number of years was registered in many experiments, however, was still rejected by mainstream science for allegedly having no consistent scientific explanation. Finally, it received the validation. Below, we outline the concept of this explanation and give the necessary calculations. This paper also considers the further destiny of the formed intermediate state of 4He∗.

  17. Commercial considerations for immunoproteomics.

    PubMed

    Ferguson, Scott M

    2013-01-01

    The underlying drivers of scientific processes have been rapidly evolving, but the ever-present need for research funding is typically foremost amongst these. Successful laboratories are embracing this reality by making certain that their projects have commercial value right from the beginning of the project conception. Which factors to be considered for commercial success need to be well thought out and incorporated into a project plan with similar levels of detail as would be the technical elements. Specific examples of commercial outcomes in the field of Immunoproteomics are exemplified in this discussion. PMID:23963949

  18. Commercial Biomedical Experiments Payload

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Experiments to seek solutions for a range of biomedical issues are at the heart of several investigations that will be hosted by the Commercial Instrumentation Technology Associates (ITA), Inc. The biomedical experiments CIBX-2 payload is unique, encompassing more than 20 separate experiments including cancer research, commercial experiments, and student hands-on experiments from 10 schools as part of ITA's ongoing University Among the stars program. Here, Astronaut Story Musgrave activates the CMIX-5 (Commercial MDA ITA experiment) payload in the Space Shuttle mid deck during the STS-80 mission in 1996 which is similar to CIBX-2. The experiments are sponsored by NASA's Space Product Development Program (SPD).

  19. Commercialization Assistance Program (CAP)

    SciTech Connect

    Jenny C. Servo, Ph.D.

    2004-07-12

    In order to fulfill the objective of Small Business Innovation Research Program (SBIR), the Department of Energy funds an initiative referred to as the Commercialization Assistance Program (CAP). The over-arching purpose of the CAP is to facilitate transition of the SBIR-funded technology to Phase III defined as private sector investment or receipt of non-sbir dollars to further the commercialization of the technology. Phase III also includes increased sales. This report summarizes the stages involved in the implementation of the Commercialization Assistance Program, a program which has been most successful in fulfilling its objectives.

  20. Fusion reactor pumped laser

    DOEpatents

    Jassby, Daniel L.

    1988-01-01

    A nuclear pumped laser capable of producing long pulses of very high power laser radiation is provided. A toroidal fusion reactor provides energetic neutrons which are slowed down by a moderator. The moderated neutrons are converted to energetic particles capable of pumping a lasing medium. The lasing medium is housed in an annular cell surrounding the reactor. The cell includes an annular reflecting mirror at the bottom and an annular output window at the top. A neutron reflector is disposed around the cell to reflect escaping neutrons back into the cell. The laser radiation from the annular window is focused onto a beam compactor which generates a single coherent output laser beam.

  1. Physics of Fusion Welding

    NASA Technical Reports Server (NTRS)

    Nunes, A. C., Jr.

    1986-01-01

    Applicabilities and limitations of three techniques analyzed. NASA technical memorandum discusses physics of electron-beam, gas/ tungsten-arc, and laser-beam welding. From comparison of capabilities and limitations of each technique with regard to various welding conditions and materials, possible to develop criteria for selecting best welding technique in specific application. All three techniques classified as fusion welding; small volume of workpiece melted by intense heat source. Heat source moved along seam, leaving in wake solid metal that joins seam edges together.

  2. Fusion energy for space: Feasibility demonstration. A proposal to NASA

    SciTech Connect

    Schulze, N.R.

    1992-10-01

    This proposed program is to initiate a space flight research and development program to develop fusion energy for the space applications of direct space propulsion and direct space power, that is, a Space Fusion Energy (SFE) program. 'Direct propulsion' refers to the use of plasma energy directly for thrust without requiring other energy conversion systems. Further, to provide space missions with large electrical power, 'direct space power' is proposed whereby the direct conversion of charged particles into electricity is used, thereby avoiding thermal conversion system losses. The energy release from nuclear fusion reactions makes these highly efficient, high power space systems possible. The program as presented conducts in an orderly, hierarchical manner the necessary planning, analyses, and testing to demonstrate the practical use of fusion energy for space. There is nothing discussed that is known to be theoretically impossible. Validation of the engineering principles is sought in this program which uses a cost-benefit approach. Upon successful program completion, space will become more accessible and space missions more safely conducted. The country will have taken a giant step toward the commercialization of space. The mission enabling capability provided by fusion energy is well beyond mission planners' current dreams.

  3. Fusion Safety Program annual report, Fiscal Year 1993

    SciTech Connect

    Longhurst, G.R.; Cadwallader, L.C.; Dolan, T.J.; Herring, J.S.; McCarthy, K.A.; Merrill, B.J.; Motloch, C.G.; Petti, D.A.

    1993-12-01

    This report summarizes the major activities of the Fusion Safety Program in Fiscal Year 1993. The Idaho National Engineering Laboratory (INEL) has been designated by DOE as the lead laboratory for fusion safety, and EG&G Idaho, Inc., is the prime contractor for INEL operations. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL and in participating organizations, including universities and private companies. Technical areas covered in the report include tritium safety, beryllium safety, activation product release, reactions involving potential plasma-facing materials, safety of fusion magnet systems, plasma disruptions and edge physics modeling, risk assessment failure rates, computer codes for reactor transient analysis, and regulatory support. These areas include work completed in support of the International Thermonuclear Experimental Reactor (ITER). Also included in the report are summaries of the safety and environmental studies performed at the INEL for the Tokamak Physics Experiment and the Tokamak Fusion Test Reactor projects at the Princeton Plasma Physics Laboratory and a summary of the technical support for the ARIES/PULSAR commercial reactor design studies.

  4. Fusion energy for space: Feasibility demonstration. A proposal to NASA

    NASA Technical Reports Server (NTRS)

    Schulze, Norman R.

    1992-01-01

    This proposed program is to initiate a space flight research and development program to develop fusion energy for the space applications of direct space propulsion and direct space power, that is, a Space Fusion Energy (SFE) program. 'Direct propulsion' refers to the use of plasma energy directly for thrust without requiring other energy conversion systems. Further, to provide space missions with large electrical power, 'direct space power' is proposed whereby the direct conversion of charged particles into electricity is used, thereby avoiding thermal conversion system losses. The energy release from nuclear fusion reactions makes these highly efficient, high power space systems possible. The program as presented conducts in an orderly, hierarchical manner the necessary planning, analyses, and testing to demonstrate the practical use of fusion energy for space. There is nothing discussed that is known to be theoretically impossible. Validation of the engineering principles is sought in this program which uses a cost-benefit approach. Upon successful program completion, space will become more accessible and space missions more safely conducted. The country will have taken a giant step toward the commercialization of space. The mission enabling capability provided by fusion energy is well beyond mission planners' current dreams.

  5. Combinatorial Fusion Analysis for Meta Search Information Retrieval

    NASA Astrophysics Data System (ADS)

    Hsu, D. Frank; Taksa, Isak

    Leading commercial search engines are built as single event systems. In response to a particular search query, the search engine returns a single list of ranked search results. To find more relevant results the user must frequently try several other search engines. A meta search engine was developed to enhance the process of multi-engine querying. The meta search engine queries several engines at the same time and fuses individual engine results into a single search results list. The fusion of multiple search results has been shown (mostly experimentally) to be highly effective. However, the question of why and how the fusion should be done still remains largely unanswered. In this chapter, we utilize the combinatorial fusion analysis proposed by Hsu et al. to analyze combination and fusion of multiple sources of information. A rank/score function is used in the design and analysis of our framework. The framework provides a better understanding of the fusion phenomenon in information retrieval. For example, to improve the performance of the combined multiple scoring systems, it is necessary that each of the individual scoring systems has relatively high performance and the individual scoring systems are diverse. Additionally, we illustrate various applications of the framework using two examples from the information retrieval domain.

  6. NASA commercial programs

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Highlights of NASA-sponsored and assisted commercial space activities of 1989 are presented. Industrial R and D in space, centers for the commercial development of space, and new cooperative agreements are addressed in the U.S. private sector in space section. In the building U.S. competitiveness through technology section, the following topics are presented: (1) technology utilization as a national priority; (2) an exploration of benefits; and (3) honoring Apollo-Era spinoffs. International and domestic R and D trends, and the space sector are discussed in the section on selected economic indicators. Other subjects included in this report are: (1) small business innovation; (2) budget highlights and trends; (3) commercial programs management; and (4) the commercial programs advisory committee.

  7. Technology Commercialization Program 1991

    SciTech Connect

    Not Available

    1991-11-01

    This reference compilation describes the Technology Commercialization Program of the Department of Energy, Defense Programs. The compilation consists of two sections. Section 1, Plans and Procedures, describes the plans and procedures of the Defense Programs Technology Commercialization Program. The second section, Legislation and Policy, identifies legislation and policy related to the Program. The procedures for implementing statutory and regulatory requirements are evolving with time. This document will be periodically updated to reflect changes and new material.

  8. Magnetless magnetic fusion

    NASA Astrophysics Data System (ADS)

    Beklemishev, A. D.; Tajima, T.

    1994-02-01

    The authors propose a concept of thermonuclear fusion reactor in which the plasma pressure is balanced by direct gas-wall interaction in a high-pressure vessel. The energy confinement is achieved by means of the self-contained toroidal magnetic configuration sustained by an external current drive or charged fusion products. This field structure causes the plasma pressure to decrease toward the inside of the discharge and thus it should be magnetohydrodynamically stable. The maximum size, temperature and density profiles of the reactor are estimated. An important feature of confinement physics is the thin layer of cold gas at the wall and the adjacent transitional region of dense arc-like plasma. The burning condition is determined by the balance between these nonmagnetized layers and the current-carrying plasma. They suggest several questions for future investigation, such as the thermal stability of the transition layer and the possibility of an effective heating and current drive behind the dense edge plasma. The main advantage of this scheme is the absence of strong external magnets and, consequently, potentially cheaper design and lower energy consumption.

  9. Multispectral bilateral video fusion.

    PubMed

    Bennett, Eric P; Mason, John L; McMillan, Leonard

    2007-05-01

    We present a technique for enhancing underexposed visible-spectrum video by fusing it with simultaneously captured video from sensors in nonvisible spectra, such as Short Wave IR or Near IR. Although IR sensors can accurately capture video in low-light and night-vision applications, they lack the color and relative luminances of visible-spectrum sensors. RGB sensors do capture color and correct relative luminances, but are underexposed, noisy, and lack fine features due to short video exposure times. Our enhanced fusion output is a reconstruction of the RGB input assisted by the IR data, not an incorporation of elements imaged only in IR. With a temporal noise reduction, we first remove shot noise and increase the color accuracy of the RGB footage. The IR video is then normalized to ensure cross-spectral compatibility with the visible-spectrum video using ratio images. To aid fusion, we decompose the video sources with edge-preserving filters. We introduce a multispectral version of the bilateral filter called the "dual bilateral" that robustly decomposes the RGB video. It utilizes the less-noisy IR for edge detection but also preserves strong visible-spectrum edges not in the IR. We fuse the RGB low frequencies, the IR texture details, and the dual bilateral edges into a noise-reduced video with sharp details, correct chrominances, and natural relative luminances. PMID:17491451

  10. Inertial confinement fusion

    SciTech Connect

    Powers, L.; Condouris, R.; Kotowski, M.; Murphy, P.W.

    1992-01-01

    This issue of the ICF Quarterly contains seven articles that describe recent progress in Lawrence Livermore National Laboratory's ICF program. The Department of Energy recently initiated an effort to design a 1--2 MJ glass laser, the proposed National Ignition Facility (NIF). These articles span various aspects of a program which is aimed at moving forward toward such a facility by continuing to use the Nova laser to gain understanding of NIF-relevant target physics, by developing concepts for an NIF laser driver, and by envisioning a variety of applications for larger ICF facilities. This report discusses research on the following topics: Stimulated Rotational Raman Scattering in Nitrogen; A Maxwell Equation Solver in LASNEX for the Simulation of Moderately Intense Ultrashort Pulse Experiments; Measurements of Radial Heat-Wave Propagation in Laser-Produced Plasmas; Laser-Seeded Modulation Growth on Directly Driven Foils; Stimulated Raman Scattering in Large-Aperture, High-Fluence Frequency-Conversion Crystals; Fission Product Hazard Reduction Using Inertial Fusion Energy; Use of Inertial Confinement Fusion for Nuclear Weapons Effects Simulations.

  11. ERC commercialization activities

    SciTech Connect

    1995-08-01

    The ERC family of companies is anticipating market entry of their first commercial product, a 2.8-MW power plant, in the second quarter of 1999. The present Cooperative Agreement provides for: (1) Commercialization planning and organizational development, (2) Completion of the pre-commercial DFC technology development, (3) Systems and plant design, (4) Manufacturing processes` scale-up to full-sized stack components and assemblies, (5) Upgrades to ERC`s test facility for full-sized stack testing, (6) Sub-scale testing of a DFC Stack and BOP fueled with landfill gas. This paper discusses the first item, that of preparing for commercialization. ERC`s formal commercialization program began in 1990 with the selection of the 2-MW Direct Fuel Cell power plant by the American Public Power Association (APPA) for promotion to the over 2000 municipal utilities comprising APPA`s segment of the utility sector. Since that beginning, the APPA core group expanded to become the Fuel Cell Commercialization Group (FCCG) which includes representation from all markets - utilities and other power generation equipment buyers.

  12. Helium Find Thaws the Cold Fusion Trail.

    ERIC Educational Resources Information Center

    Pennisi, E.

    1991-01-01

    Reported is a study of cold fusion in which trace amounts of helium, possible evidence of an actual fusion reaction, were found. Research methodology is detailed. The controversy over the validity of experimental results with cold fusion are reviewed. (CW)

  13. Multi-sensor fusion development

    NASA Astrophysics Data System (ADS)

    Bish, Sheldon; Rohrer, Matthew; Scheffel, Peter; Bennett, Kelly

    2016-05-01

    The U.S. Army Research Laboratory (ARL) and McQ Inc. are developing a generic sensor fusion architecture that involves several diverse processes working in combination to create a dynamic task-oriented, real-time informational capability. Processes include sensor data collection, persistent and observational data storage, and multimodal and multisensor fusion that includes the flexibility to modify the fusion program rules for each mission. Such a fusion engine lends itself to a diverse set of sensing applications and architectures while using open-source software technologies. In this paper, we describe a fusion engine architecture that combines multimodal and multi-sensor fusion within an Open Standard for Unattended Sensors (OSUS) framework. The modular, plug-and-play architecture of OSUS allows future fusion plugin methodologies to have seamless integration into the fusion architecture at the conceptual and implementation level. Although beyond the scope of this paper, this architecture allows for data and information manipulation and filtering for an array of applications.

  14. The status of cold fusion

    NASA Astrophysics Data System (ADS)

    Storms, E.

    This report attempts to update the status of the phenomenon of cold fusion. The new field is continuing to grow as a variety of nuclear reactions are discovered to occur in a variety of chemical environments at modest temperatures. However, it must be cautioned that most scientists consider cold fusion as something akin to UFO's, ESP, and numerology.

  15. Data fusion qualitative sensitivity analysis

    SciTech Connect

    Clayton, E.A.; Lewis, R.E.

    1995-09-01

    Pacific Northwest Laboratory was tasked with testing, debugging, and refining the Hanford Site data fusion workstation (DFW), with the assistance of Coleman Research Corporation (CRC), before delivering the DFW to the environmental restoration client at the Hanford Site. Data fusion is the mathematical combination (or fusion) of disparate data sets into a single interpretation. The data fusion software used in this study was developed by CRC. The data fusion software developed by CRC was initially demonstrated on a data set collected at the Hanford Site where three types of data were combined. These data were (1) seismic reflection, (2) seismic refraction, and (3) depth to geologic horizons. The fused results included a contour map of the top of a low-permeability horizon. This report discusses the results of a sensitivity analysis of data fusion software to variations in its input parameters. The data fusion software developed by CRC has a large number of input parameters that can be varied by the user and that influence the results of data fusion. Many of these parameters are defined as part of the earth model. The earth model is a series of 3-dimensional polynomials with horizontal spatial coordinates as the independent variables and either subsurface layer depth or values of various properties within these layers (e.g., compression wave velocity, resistivity) as the dependent variables.

  16. Cellulose binding domain fusion proteins

    DOEpatents

    Shoseyov, O.; Yosef, K.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.

    1998-02-17

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 16 figs.

  17. Cellulose binding domain fusion proteins

    DOEpatents

    Shoseyov, Oded; Shpiegl, Itai; Goldstein, Marc A.; Doi, Roy H.

    1998-01-01

    A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.

  18. Cold fusion; Myth versus reality

    SciTech Connect

    Rabinowitz, M. )

    1990-01-01

    Experiments indicate that several different nuclear reactions are taking place. Some of the experiments point to D-D fusion with a cominant tritium channel as one of the reactions. The article notes a similarity between Prometheus and the discoveries of cold fusion.

  19. Deployment of membrane fusion protein domains during fusion.

    PubMed

    Bentz, J; Mittal, A

    2000-01-01

    It is clear that both viral and intracellular membrane fusion proteins contain a minimal set of domains which must be deployed at the appropriate time during the fusion process. An account of these domains and their functions is given here for the four best-described fusion systems: influenza HA, sendai virus F1, HIV gp120/41 and the neuronal SNARE core composed of synaptobrevin (syn), syntaxin (stx) and the N- and C-termini of SNAP25 (sn25), together with the Ca(2+)binding protein synaptotagmin (syt). Membrane fusion begins with the binding of the virion or vesicle to the target membrane via receptors. The committed step in influenza HA- mediated fusion begins with an aggregate of HAs (at least eight) with some of their HA2 N-termini, a.k.a. fusion peptides, embedded into the viral bilayer (Bentz, 2000 a). The hypothesis presented in Bentz (2000 b) is that the conformational change of HA to the extended coiled coil extracts the fusion peptides from the viral bilayer. When this extraction occurs from the center of the site of restricted lipid flow, it exposes acyl chains and parts of the HA transmembrane domains to the aqueous media, i.e. a hydrophobic defect is formed. This is the 'transition state' of the committed step of fusion. It is stabilized by a 'dam' of HAs, which are inhibited from diffusing away by the rest of the HAs in the aggregate and because that would initially expose more acyl chains to water. Recruitment of lipids from the apposed target membrane can heal this hydrophobic defect, initiating lipid mixing and fusion. The HA transmembrane domains are required to be part of the hydrophobic defect, because the HA aggregate must be closely packed enough to restrict lipid flow. This hypothesis provides a simple and direct coupling between the energy released by the formation of the coiled coil to the energy needed to create and stabilize the high energy intermediates of fusion. Several of these essential domains have been described for the viral fusion

  20. Magnetic fusion energy and computers

    SciTech Connect

    Killeen, J.

    1982-01-01

    The application of computers to magnetic fusion energy research is essential. In the last several years the use of computers in the numerical modeling of fusion systems has increased substantially. There are several categories of computer models used to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies are also in use. To meet the needs of the fusion program, the National Magnetic Fusion Energy Computer Center has been established at the Lawrence Livermore National Laboratory. A large central computing facility is linked to smaller computer centers at each of the major MFE laboratories by a communication network. In addition to providing cost effective computing services, the NMFECC environment stimulates collaboration and the sharing of computer codes among the various fusion research groups.

  1. Information integration for data fusion

    SciTech Connect

    Bray, O.H.

    1997-01-01

    Data fusion has been identified by the Department of Defense as a critical technology for the U.S. defense industry. Data fusion requires combining expertise in two areas - sensors and information integration. Although data fusion is a rapidly growing area, there is little synergy and use of common, reusable, and/or tailorable objects and models, especially across different disciplines. The Laboratory-Directed Research and Development project had two purposes: to see if a natural language-based information modeling methodology could be used for data fusion problems, and if so, to determine whether this methodology would help identify commonalities across areas and achieve greater synergy. The project confirmed both of the initial hypotheses: that the natural language-based information modeling methodology could be used effectively in data fusion areas and that commonalities could be found that would allow synergy across various data fusion areas. The project found five common objects that are the basis for all of the data fusion areas examined: targets, behaviors, environments, signatures, and sensors. Many of the objects and the specific facts related to these objects were common across several areas and could easily be reused. In some cases, even the terminology remained the same. In other cases, different areas had their own terminology, but the concepts were the same. This commonality is important with the growing use of multisensor data fusion. Data fusion is much more difficult if each type of sensor uses its own objects and models rather than building on a common set. This report introduces data fusion, discusses how the synergy generated by this LDRD would have benefited an earlier successful project and contains a summary information model from that project, describes a preliminary management information model, and explains how information integration can facilitate cross-treaty synergy for various arms control treaties.

  2. Innovative energy production in fusion reactors

    NASA Astrophysics Data System (ADS)

    Iiyoshi, A.; Momota, H.; Motojima, O.; Okamoto, M.; Sudo, S.; Tomita, Y.; Yamaguchi, S.; Ohnishi, M.; Onozuka, M.; Uenosono, C.

    1993-10-01

    Concepts of innovative energy production in neutron-lean fusion reactors without having the conventional turbine-type generator are proposed for improving the plant efficiency. These concepts are: (1) traveling wave direct energy conversion of 14.7 MeV protons; (2) cusp type direct energy conversion of charged particles; (3) efficient use of radiation with semiconductor and supplying clean fuel in a form of hydrogen gas; and (4) direct energy conversion from deposited heat to electric power with semiconductor utilizing Nernst effect. The candidates of reactors such as a toroidal system and an open system are also studied for application of the new concepts. The study shows the above concepts for a commercial reactor are promising.

  3. Innovative insulation systems for superconducting fusion magnets

    NASA Astrophysics Data System (ADS)

    Humer, K.; Bittner-Rohrhofer, K.; Fillunger, H.; Maix, R. K.; Prokopec, R.; Weber, H. W.

    2006-03-01

    Glass fibre reinforced plastics (GFRPs) are usually employed as insulating materials for the superconducting coils of large fusion magnets, e.g. of the International Thermonuclear Experimental Reactor (ITER). Both the radiation spectrum and the stresses at the magnet location significantly influence the mechanical behaviour of the magnet insulation and, therefore, impose high demands on the material performance. During the last few decades, advanced epoxy based GFRPs with improved mechanical properties and radiation hardness were introduced into fusion technology. More recently, cyanate ester (CE) matrix systems have become of special interest. In this paper, various magnet insulation systems containing boron-free R-glass fibre reinforcements in commercial and new epoxies as well as in pure CE and CE/epoxy blended matrix systems are presented. All systems were irradiated in a fission reactor at ambient temperature (~340 K) to a fast neutron fluence of 1 × 1022 m-2 (E>0.1 MeV). The mechanical properties were assessed at 77 K in tension as well as in interlaminar shear prior to and after irradiation under static and dynamic conditions.

  4. Commercialization of animal biotechnology.

    PubMed

    Faber, D C; Molina, J A; Ohlrichs, C L; Vander Zwaag, D F; Ferré, L B

    2003-01-01

    Commercialization of animal biotechnology is a wide-ranging topic for discussion. In this paper, we will attempt to review embryo transfer (ET) and related technologies that relate to food-producing mammals. A brief review of the history of advances in biotechnology will provide a glimpse to present and future applications. Commercialization of animal biotechnology is presently taking two pathways. The first application involves the use of animals for biomedical purposes. Very few companies have developed all of the core competencies and intellectual properties to complete the bridge from lab bench to product. The second pathway of application is for the production of animals used for food. Artificial insemination (AI), embryo transfer, in vitro fertilization (IVF), cloning, transgenics, and genomics all are components of the toolbox for present and future applications. Individually, these are powerful tools capable of providing significant improvements in productivity. Combinations of these technologies coupled with information systems and data analysis, will provide even more significant change in the next decade. Any strategies for the commercial application of animal biotechnology must include a careful review of regulatory and social concerns. Careful review of industry infrastructure is also important. Our colleagues in plant biotechnology have helped highlight some of these pitfalls and provide us with a retrospective review. In summary, today we have core competencies that provide a wealth of opportunities for the members of this society, commercial companies, producers, and the general population. Successful commercialization will benefit all of the above stakeholders. PMID:12499024

  5. Multiple shell fusion targets

    DOEpatents

    Lindl, J.D.; Bangerter, R.O.

    1975-10-31

    Multiple shell fusion targets for use with electron beam and ion beam implosion systems are described. The multiple shell targets are of the low-power type and use a separate relatively low Z, low density ablator at large radius for the outer shell, which reduces the focusing and power requirements of the implosion system while maintaining reasonable aspect ratios. The targets use a high Z, high density pusher shell placed at a much smaller radius in order to obtain an aspect ratio small enough to protect against fluid instability. Velocity multiplication between these shells further lowers the power requirements. Careful tuning of the power profile and intershell density results in a low entropy implosion which allows breakeven at low powers. For example, with ion beams as a power source, breakeven at 10-20 Terrawatts with 10 MeV alpha particles for imploding a multiple shell target can be accomplished.

  6. Fusion pumped laser

    DOEpatents

    Pappas, Daniel S.

    1989-01-01

    Apparatus is provided for generating energy in the form of laser radiation. A tokamak fusion reactor is provided for generating a long, or continuous, pulse of high-energy neutrons. The tokamak design provides a temperature and a magnetic field which is effective to generate a neutron flux of at least 10.sup.15 neutrons/cm.sup.2.s. A conversion medium receives neutrons from the tokamak and converts the high-energy neutrons to an energy source with an intensity and an energy effective to excite a preselected lasing medium. The energy source typically comprises fission fragments, alpha particles, and radiation from a fission event. A lasing medium is provided which is responsive to the energy source to generate a population inversion which is effective to support laser oscillations for generating output radiation.

  7. Fusion reactor pumped laser

    DOEpatents

    Jassby, D.L.

    1987-09-04

    A nuclear pumped laser capable of producing long pulses of very high power laser radiation is provided. A toroidal fusion reactor provides energetic neutrons which are slowed down by a moderator. The moderated neutrons are converted to energetic particles capable of pumping a lasing medium. The lasing medium is housed in an annular cell surrounding the reactor. The cell includes an annular reflecting mirror at the bottom and an annular output window at the top. A neutron reflector is disposed around the cell to reflect escaping neutrons back into the cell. The laser radiation from the annular window is focused onto a beam compactor which generates a single coherent output laser beam. 10 figs.

  8. Fusion pumped light source

    DOEpatents

    Pappas, Daniel S.

    1989-01-01

    Apparatus is provided for generating energy in the form of light radiation. A fusion reactor is provided for generating a long, or continuous, pulse of high-energy neutrons. The neutron flux is coupled directly with the lasing medium. The lasing medium includes a first component selected from Group O of the periodic table of the elements and having a high inelastic scattering cross section. Gamma radiation from the inelastic scattering reactions interacts with the first component to excite the first component, which decays by photon emission at a first output wavelength. The first output wavelength may be shifted to a second output wavelength using a second liquid component responsive to the first output wavelength. The light outputs may be converted to a coherent laser output by incorporating conventional optics adjacent the laser medium.

  9. LiWall Fusion - The New Concept of Magnetic Fusion

    SciTech Connect

    L.E. Zakharov

    2011-01-12

    Utilization of the outstanding abilities of a liquid lithium layer in pumping hydrogen isotopes leads to a new approach to magnetic fusion, called the LiWall Fusion. It relies on innovative plasma regimes with low edge density and high temperature. The approach combines fueling the plasma by neutral injection beams with the best possible elimination of outside neutral gas sources, which cools down the plasma edge. Prevention of cooling the plasma edge suppresses the dominant, temperature gradient related turbulence in the core. Such an approach is much more suitable for controlled fusion than the present practice, relying on high heating power for compensating essentially unlimited turbulent energy losses.

  10. Prospects for bubble fusion

    SciTech Connect

    Nigmatulin, R.I.; Lahey, R.T. Jr.

    1995-09-01

    In this paper a new method for the realization of fusion energy is presented. This method is based on the superhigh compression of a gas bubble (deuterium or deuterium/thritium) in heavy water or another liquid. The superhigh compression of a gas bubble in a liquid is achieved through forced non-linear, non-periodic resonance oscillations using moderate amplitudes of forcing pressure. The key feature of this new method is a coordination of the forced liquid pressure change with the change of bubble volume. The corresponding regime of the bubble oscillation has been called {open_quotes}basketball dribbling (BD) regime{close_quotes}. The analytical solution describing this process for spherically symmetric bubble oscillations, neglecting dissipation and compressibility of the liquid, has been obtained. This solution shown no limitation on the supercompression of the bubble and the corresponding maximum temperature. The various dissipation mechanisms, including viscous, conductive and radiation heat losses have been considered. It is shown that in spite of these losses it is possible to achieve very high gas bubble temperatures. This because the time duration of the gas bubble supercompression becomes very short when increasing the intensity of compression, thus limiting the energy losses. Significantly, the calculated maximum gas temperatures have shown that nuclear fusion may be possible. First estimations of the affect of liquid compressibility have been made to determine possible limitations on gas bubble compression. The next step will be to investigate the role of interfacial instability and breaking down of the bubble, shock wave phenomena around and in the bubble and mutual diffusion of the gas and the liquid.

  11. Fission-fusion neutron source

    NASA Astrophysics Data System (ADS)

    Yu, Jinnan; Yu, Gang

    2009-04-01

    In order to meet the requirements of fusion power reactors and nuclear waste treatment, a concept of fission-fusion neutron source is proposed, which consists of a LiD assembly located in the heavy water region of the China Advanced Research Reactor. This assembly of LiD fuel rods will be irradiated with slow neutrons and will produce fusion neutrons in the central hole via the reaction 6Li(n, α). More precisely, tritium ions with a high energy of 2.739 MeV will be produced in LiD by the impinging slow neutrons. The tritium ions will in turn bombard the deuterium ions present in the LiD assembly, which will induce fusion reaction and then the production of 14 MeV neutrons. The fusion reaction rate will increase with the accumulation of tritium in LiD by the reaction between tritium and deuteron recoils produced by the 14 MeV neutrons. When the concentration of tritium reaches 0.5 · 10 22 and the fraction of fusion reactions between tritium and deuteron recoils approaches 1, the 14 MeV neutron flux is doubled and redoubled, an so forth, approaching saturation in which the tritium produced at a time t is exhausted by the fusion reactions to keep constant the tritium concentration in LiD.

  12. Future of Inertial Fusion Energy

    SciTech Connect

    Nuckolls, J H; Wood, L L

    2002-09-04

    In the past 50 years, fusion R&D programs have made enormous technical progress. Projected billion-dollar scale research facilities are designed to approach net energy production. In this century, scientific and engineering progress must continue until the economics of fusion power plants improves sufficiently to win large scale private funding in competition with fission and non-nuclear energy systems. This economic advantage must be sustained: trillion dollar investments will be required to build enough fusion power plants to generate ten percent of the world's energy. For Inertial Fusion Energy, multi-billion dollar driver costs must be reduced by up to an order of magnitude, to a small fraction of the total cost of the power plant. Major cost reductions could be achieved via substantial improvements in target performance-both higher gain and reduced ignition energy. Large target performance improvements may be feasible through a combination of design innovations, e.g., ''fast ignition,'' propagation down density gradients, and compression of fusion fuel with a combination of driver and chemical energy. The assumptions that limit projected performance of fusion targets should be carefully examined. The National Ignition Facility will enable development and testing of revolutionary targets designed to make possible economically competitive fusion power plants.

  13. Poxvirus entry and membrane fusion

    SciTech Connect

    Moss, Bernard . E-mail: bmoss@nih.gov

    2006-01-05

    The study of poxvirus entry and membrane fusion has been invigorated by new biochemical and microscopic findings that lead to the following conclusions: (1) the surface of the mature virion (MV), whether isolated from an infected cell or by disruption of the membrane wrapper of an extracellular virion, is comprised of a single lipid membrane embedded with non-glycosylated viral proteins; (2) the MV membrane fuses with the cell membrane, allowing the core to enter the cytoplasm and initiate gene expression; (3) fusion is mediated by a newly recognized group of viral protein components of the MV membrane, which are conserved in all members of the poxvirus family; (4) the latter MV entry/fusion proteins are required for cell to cell spread necessitating the disruption of the membrane wrapper of extracellular virions prior to fusion; and furthermore (5) the same group of MV entry/fusion proteins are required for virus-induced cell-cell fusion. Future research priorities include delineation of the roles of individual entry/fusion proteins and identification of cell receptors.

  14. Commercial Biomedical Experiments

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Experiments to seek solutions for a range of biomedical issues are at the heart of several investigations that will be hosted by the Commercial Instrumentation Technology Associates (ITA), Inc. Biomedical Experiments (CIBX-2) payload. CIBX-2 is unique, encompassing more than 20 separate experiments including cancer research, commercial experiments, and student hands-on experiments from 10 schools as part of ITA's ongoing University Among the Stars program. Valerie Cassanto of ITA checks the Canadian Protein Crystallization Experiment (CAPE) carried by STS-86 to Mir in 1997. The experiments are sponsored by NASA's Space Product Development Program (SPD).

  15. Commercial Fisheries Surveys

    USGS Publications Warehouse

    Fabrizio, Mary C.; Richards, R. Anne; Murphy, Brian R.; Willis, David W.

    1996-01-01

    In this chapter, we describe methods for sampling commercial fisheries and identify factors affecting the design of sampling plans. When sampled properly, commercial fisheries can provide important information on the response of aquatic organisms to exploitation; such information can be used by management agencies to develop regulations for ensuring long-term production of the resource and long-term economic benefit. Fishery statistics are typically used to estimate abundance, mortality, recruitment, growth, and other vital characterisitcs of populations. Fishery statistics can also be used to study changes in fish community composition resulting from differential exploitation of species.

  16. Control of mechanically activated polymersome fusion: Factors affecting fusion

    SciTech Connect

    Henderson, Ian M.; Paxton, Walter F.

    2014-12-15

    Previously we have studied the mechanically-activated fusion of extruded (200 nm) polymer vesicles into giant polymersomes using agitation in the presence of salt. In this study we have investigated several factors contributing to this phenomenon, including the effects of (i) polymer vesicle concentration, (ii) agitation speed and duration, and iii) variation of the salt and its concentration. It was found that increasing the concentration of the polymer dramatically increases the production of giant vesicles through the increased collisions of polymersomes. Our investigations also found that increasing the frequency of agitation increased the efficiency of fusion, though ultimately limited the size of vesicle which could be produced due to the high shear involved. Finally it was determined that salt-mediation of the fusion process was not limited to NaCl, but is instead a general effect facilitated by the presence of solvated ionic compounds, albeit with different salts initiating fusion at different concentration.

  17. Control of mechanically activated polymersome fusion: Factors affecting fusion

    DOE PAGES

    Henderson, Ian M.; Paxton, Walter F.

    2014-12-15

    Previously we have studied the mechanically-activated fusion of extruded (200 nm) polymer vesicles into giant polymersomes using agitation in the presence of salt. In this study we have investigated several factors contributing to this phenomenon, including the effects of (i) polymer vesicle concentration, (ii) agitation speed and duration, and iii) variation of the salt and its concentration. It was found that increasing the concentration of the polymer dramatically increases the production of giant vesicles through the increased collisions of polymersomes. Our investigations also found that increasing the frequency of agitation increased the efficiency of fusion, though ultimately limited the sizemore » of vesicle which could be produced due to the high shear involved. Finally it was determined that salt-mediation of the fusion process was not limited to NaCl, but is instead a general effect facilitated by the presence of solvated ionic compounds, albeit with different salts initiating fusion at different concentration.« less

  18. Pubertal growth and epiphyseal fusion

    PubMed Central

    2015-01-01

    The complex networks of nutritional, cellular, paracrine, and endocrine factors are closely related with pubertal growth and epiphyseal fusion. Important influencing factors include chondrocyte differentiation capacity, multiple molecular pathways active in the growth plate, and growth hormone-insulin-like growth factor-I axis activation and epiphyseal fusion through estrogen and its receptors. However, the exact mechanisms of these phenomena are still unclear. A better understanding of the detailed processes involved in the pubertal growth spurt and growth plate closure in longitudinal bone growth will help us develop methods to efficiently promote pubertal growth and delay epiphyseal fusion with fewer adverse effects. PMID:25883921

  19. The path to fusion power†

    PubMed Central

    Smith, Chris Llewellyn; Cowley, Steve

    2010-01-01

    The promise, status and challenges of developing fusion power are outlined. The key physics and engineering principles are described and recent progress quantified. As the successful demonstration of 16 MW of fusion in 1997 in the Joint European Torus showed, fusion works. The central issue is therefore to make it work reliably and economically on the scale of a power station. We argue that to meet this challenge in 30 years we must follow the aggressive programme known as the ‘Fast Track to Fusion’. This programme is described in some detail. PMID:20123748

  20. Advanced fusion concepts: project summaries

    SciTech Connect

    1980-12-01

    This report contains descriptions of the activities of all the projects supported by the Advanced Fusion Concepts Branch of the Office of Fusion Energy, US Department of Energy. These descriptions are project summaries of each of the individual projects, and contain the following: title, principle investigators, funding levels, purpose, approach, progress, plans, milestones, graduate students, graduates, other professional staff, and recent publications. Information is given for each of the following programs: (1) reverse-field pinch, (2) compact toroid, (3) alternate fuel/multipoles, (4) stellarator/torsatron, (5) linear magnetic fusion, (6) liners, and (7) Tormac. (MOW)

  1. A cost-effective target supply for inertial fusion energy

    NASA Astrophysics Data System (ADS)

    Goodin, D. T.; Alexander, N. B.; Brown, L. C.; Frey, D. T.; Gallix, R.; Gibson, C. R.; Maxwell, J. L.; Nobile, A.; Olson, C.; Petzoldt, R. W.; Raffray, R.; Rochau, G.; Schroen, D. G.; Tillack, M.; Rickman, W. S.; Vermillion, B.

    2004-12-01

    A central feature of an inertial fusion energy (IFE) power plant is a target that has been compressed and heated to fusion conditions by the energy input of the driver. This is true whether the driver is a laser system, heavy ion beams or Z-pinch system. The IFE target fabrication, injection and tracking programmes are focusing on methods that will scale to mass production. We are working closely with target designers, and power plant systems specialists, to make specifications and material selections that will satisfy a wide range of required and desirable target characteristics. One-of-a-kind capsules produced for today's inertial confinement fusion experiments are estimated to cost about US2500 each. Design studies of cost-effective power production from laser and heavy-ion driven IFE have suggested a cost goal of about 0.25-0.30 for each injected target (corresponding to ~10% of the 'electricity value' in a target). While a four orders of magnitude cost reduction may seem at first to be nearly impossible, there are many factors that suggest this is achievable. This paper summarizes the design, specifications, requirements and proposed manufacturing processes for the future for laser fusion, heavy ion fusion and Z-pinch driven targets. These target manufacturing processes have been developed—and are proposed—based on the unique materials science and technology programmes that are ongoing for each of the target concepts. We describe the paradigm shifts in target manufacturing methodologies that will be needed to achieve orders of magnitude reductions in target costs, and summarize the results of 'nth-of-a-kind' plant layouts and cost estimates for future IFE power plant fuelling. These engineering studies estimate the cost of the target supply in a fusion economy, and show that costs are within the range of commercial feasibility for electricity production.

  2. Commercial and Industrial Wiring.

    ERIC Educational Resources Information Center

    Kaltwasser, Stan; Flowers, Gary

    This module is the third in a series of three wiring publications, includes additional technical knowledge and applications required for job entry in the commercial and industrial wiring trade. The module contains 15 instructional units that cover the following topics: blueprint reading and load calculations; tools and equipment; service;…

  3. Commercial Carpentry: Instructional Units.

    ERIC Educational Resources Information Center

    Diehl, Donald W.; Penner, Wayman R.

    This manual contains instructional materials which measure student performance on commercial carpentry behavioral objectives; criterion-referenced evaluation instruments are also included. Each of the manual's eleven sections consists of one or more units of instruction. Each instructional unit includes behavioral objectives, suggested activities…

  4. Commercial Earth Observation

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Through the Earth Observation Commercial Applications Program (EOCAP) at Stennis Space Center, Applied Analysis, Inc. developed a new tool for analyzing remotely sensed data. The Applied Analysis Spectral Analytical Process (AASAP) detects or classifies objects smaller than a pixel and removes the background. This significantly enhances the discrimination among surface features in imagery. ERDAS, Inc. offers the system as a modular addition to its ERDAS IMAGINE software package for remote sensing applications. EOCAP is a government/industry cooperative program designed to encourage commercial applications of remote sensing. Projects can run three years or more and funding is shared by NASA and the private sector participant. Through the Earth Observation Commercial Applications Program (EOCAP), Ocean and Coastal Environmental Sensing (OCENS) developed SeaStation for marine users. SeaStation is a low-cost, portable, shipboard satellite groundstation integrated with vessel catch and product monitoring software. Linked to the Global Positioning System, SeaStation provides real time relationships between vessel position and data such as sea surface temperature, weather conditions and ice edge location. This allows the user to increase fishing productivity and improve vessel safety. EOCAP is a government/industry cooperative program designed to encourage commercial applications of remote sensing. Projects can run three years or more and funding is shared by NASA and the private sector participant.

  5. Commercial Baking. Final Report.

    ERIC Educational Resources Information Center

    Booth, Nancy

    A project filmed three commercial baking videotapes for use by secondary and adult students in food service programs. The three topics were basic dinner rolls, bread making, and hard breads and rolls. Quick-rise dough recipes were developed, written down, and explained for use with the videotapes. A pretest, posttest, and student guide were…

  6. Commercial Crew Medical Ops

    NASA Technical Reports Server (NTRS)

    Heinbaugh, Randall; Cole, Richard

    2016-01-01

    Provide commercial partners with: center insight into NASA spaceflight medical experience center; information relative to both nominal and emergency care of the astronaut crew at landing site center; a basis for developing and sharing expertise in space medical factors associated with returning crew.

  7. Commercial applications of telemedicine

    NASA Technical Reports Server (NTRS)

    Natiello, Thomas A.

    1991-01-01

    Telemedicine Systems Corporation was established in 1976 and is a private commercial supplier of telemedicine systems. These systems are various combinations of communications and diagnostic technology, designed to allow the delivery of health care services to remote facilities. The technology and the health care services are paid for by the remote facilities, such as prisons.

  8. Commercializing Biological Control

    ERIC Educational Resources Information Center

    LeLeu, K. L.; Young, M. A.

    1973-01-01

    Describes the only commercial establishment involved in biological control in Australia. The wasp Aphitis melinus, which parasitizes the insect Red Scale, is bred in large numbers and released in the citrus groves where Red Scale is causing damage to the fruit. (JR)

  9. Fusion materials irradiations at MaRIE's fission fusion facility

    SciTech Connect

    Pitcher, Eric J

    2010-10-06

    Los Alamos National Laboratory's proposed signature facility, MaRIE, will provide scientists and engineers with new capabilities for modeling, synthesizing, examining, and testing materials of the future that will enhance the USA's energy security and national security. In the area of fusion power, the development of new structural alloys with better tolerance to the harsh radiation environments expected in fusion reactors will lead to improved safety and lower operating costs. The Fission and Fusion Materials Facility (F{sup 3}), one of three pillars of the proposed MaRIE facility, will offer researchers unprecedented access to a neutron radiation environment so that the effects of radiation damage on materials can be measured in-situ, during irradiation. The calculated radiation damage conditions within the F{sup 3} match, in many respects, that of a fusion reactor first wall, making it well suited for testing fusion materials. Here we report in particular on two important characteristics of the radiation environment with relevancy to radiation damage: the primary knock-on atom spectrum and the impact of the pulse structure of the proton beam on temporal characteristics of the atomic displacement rate. With respect to both of these, analyses show the F{sup 3} has conditions that are consistent with those of a steady-state fusion reactor first wall.

  10. A1.5 Fusion Performance

    SciTech Connect

    Amendt, P

    2011-03-31

    Analysis and radiation hydrodynamics simulations for expected high-gain fusion target performance on a demonstration 1-GWe Laser Inertial Fusion Energy (LIFE) power plant in the mid-2030s timeframe are presented. The required laser energy driver is 2.2 MJ at a 0.351-{micro}m wavelength, and a fusion target gain greater than 60 at a repetition rate of 16 Hz is the design goal for economic and commercial attractiveness. A scaling-law analysis is developed to benchmark the design parameter space for hohlraum-driven central hot-spot ignition. A suite of integrated hohlraum simulations is presented to test the modeling assumptions and provide a basis for a near-term experimental resolution of the key physics uncertainties on the National Ignition Facility (NIF). The NIF is poised to demonstrate ignition by 2012 based on the central hot spot (CHS) mode of ignition and propagating thermonuclear burn [1]. This immediate prospect underscores the imperative and timeliness of advancing inertial fusion as a carbon-free, virtually limitless source of energy by the mid-21st century to substantially offset fossil fuel technologies. To this end, an intensive effort is underway to leverage success at the NIF and to provide the foundations for a prototype 'LIFE.1' engineering test facility by {approx}2025, followed by a commercially viable 'LIFE.2' demonstration power plant operating at 1 GWe by {approx}2035. The current design goal for LIFE.2 is to accommodate {approx}2.2 MJ of laser energy (entering the high-Z radiation enclosure or 'hohlraum') at a 0.351-{micro}m wavelength operating at a repetition rate of 16 Hz and to provide a fusion target yield of 132 MJ. To achieve this design goal first requires a '0-d' analytic gain model that allows convenient exploration of parameter space and target optimization. This step is then followed by 2- and 3-dimensional radiation-hydrodynamics simulations that incorporate laser beam transport, x-ray radiation transport, atomic physics, and

  11. Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing.

    PubMed

    Weirather, Jason L; Afshar, Pegah Tootoonchi; Clark, Tyson A; Tseng, Elizabeth; Powers, Linda S; Underwood, Jason G; Zabner, Joseph; Korlach, Jonas; Wong, Wing Hung; Au, Kin Fai

    2015-10-15

    We developed an innovative hybrid sequencing approach, IDP-fusion, to detect fusion genes, determine fusion sites and identify and quantify fusion isoforms. IDP-fusion is the first method to study gene fusion events by integrating Third Generation Sequencing long reads and Second Generation Sequencing short reads. We applied IDP-fusion to PacBio data and Illumina data from the MCF-7 breast cancer cells. Compared with the existing tools, IDP-fusion detects fusion genes at higher precision and a very low false positive rate. The results show that IDP-fusion will be useful for unraveling the complexity of multiple fusion splices and fusion isoforms within tumorigenesis-relevant fusion genes. PMID:26040699

  12. Characterization of fusion genes and the significantly expressed fusion isoforms in breast cancer by hybrid sequencing

    PubMed Central

    Weirather, Jason L.; Afshar, Pegah Tootoonchi; Clark, Tyson A.; Tseng, Elizabeth; Powers, Linda S.; Underwood, Jason G.; Zabner, Joseph; Korlach, Jonas; Wong, Wing Hung; Au, Kin Fai

    2015-01-01

    We developed an innovative hybrid sequencing approach, IDP-fusion, to detect fusion genes, determine fusion sites and identify and quantify fusion isoforms. IDP-fusion is the first method to study gene fusion events by integrating Third Generation Sequencing long reads and Second Generation Sequencing short reads. We applied IDP-fusion to PacBio data and Illumina data from the MCF-7 breast cancer cells. Compared with the existing tools, IDP-fusion detects fusion genes at higher precision and a very low false positive rate. The results show that IDP-fusion will be useful for unraveling the complexity of multiple fusion splices and fusion isoforms within tumorigenesis-relevant fusion genes. PMID:26040699

  13. Prospects for fusion: The winds of change

    NASA Astrophysics Data System (ADS)

    Davidson, R. C.

    This paper addresses the following topics: (1) national energy circumstances and policy, and the implications for fusion; (2) the intrinsic merit of fusion research and development as it contributes to the national science and technology base; (3) the research opportunities and priorities in inertial confinement fusion; and (4) the research opportunities and priorities in magnetic fusion.

  14. Lunar Commercial Mining Logistics

    NASA Astrophysics Data System (ADS)

    Kistler, Walter P.; Citron, Bob; Taylor, Thomas C.

    2008-01-01

    Innovative commercial logistics is required for supporting lunar resource recovery operations and assisting larger consortiums in lunar mining, base operations, camp consumables and the future commercial sales of propellant over the next 50 years. To assist in lowering overall development costs, ``reuse'' innovation is suggested in reusing modified LTS in-space hardware for use on the moon's surface, developing product lines for recovered gases, regolith construction materials, surface logistics services, and other services as they evolve, (Kistler, Citron and Taylor, 2005) Surface logistics architecture is designed to have sustainable growth over 50 years, financed by private sector partners and capable of cargo transportation in both directions in support of lunar development and resource recovery development. The author's perspective on the importance of logistics is based on five years experience at remote sites on Earth, where remote base supply chain logistics didn't always work, (Taylor, 1975a). The planning and control of the flow of goods and materials to and from the moon's surface may be the most complicated logistics challenges yet to be attempted. Affordability is tied to the innovation and ingenuity used to keep the transportation and surface operations costs as low as practical. Eleven innovations are proposed and discussed by an entrepreneurial commercial space startup team that has had success in introducing commercial space innovation and reducing the cost of space operations in the past. This logistics architecture offers NASA and other exploring nations a commercial alternative for non-essential cargo. Five transportation technologies and eleven surface innovations create the logistics transportation system discussed.

  15. Condensed hydrogen for thermonuclear fusion

    SciTech Connect

    Kucheyev, S. O.; Hamza, A. V.

    2010-11-15

    Inertial confinement fusion (ICF) power, in either pure fusion or fission-fusion hybrid reactors, is a possible solution for future world's energy demands. Formation of uniform layers of a condensed hydrogen fuel in ICF targets has been a long standing materials physics challenge. Here, we review the progress in this field. After a brief discussion of the major ICF target designs and the basic properties of condensed hydrogens, we review both liquid and solid layering methods, physical mechanisms causing layer nonuniformity, growth of hydrogen single crystals, attempts to prepare amorphous and nanostructured hydrogens, and mechanical deformation behavior. Emphasis is given to current challenges defining future research areas in the field of condensed hydrogens for fusion energy applications.

  16. Membrane tension and membrane fusion.

    PubMed

    Kozlov, Michael M; Chernomordik, Leonid V

    2015-08-01

    Diverse cell biological processes that involve shaping and remodeling of cell membranes are regulated by membrane lateral tension. Here we focus on the role of tension in driving membrane fusion. We discuss the physics of membrane tension, forces that can generate the tension in plasma membrane of a cell, and the hypothesis that tension powers expansion of membrane fusion pores in late stages of cell-to-cell and exocytotic fusion. We propose that fusion pore expansion can require unusually large membrane tensions or, alternatively, low line tensions of the pore resulting from accumulation in the pore rim of membrane-bending proteins. Increase of the inter-membrane distance facilitates the reaction. PMID:26282924

  17. Information fusion for palmprint authentication

    NASA Astrophysics Data System (ADS)

    Wu, Xiangqian; Wang, Kuanquan; Zhang, David

    2006-04-01

    A palmprint can be represented using different features and the different representations reflect the different characteristic of a palmprint. Fusion of multiple palmprint features may enhance the performance of a palmprint authentication system. This paper investigates the fusion of two types of palmprint information: the phase (called PalmCode) and the orientation (called OrientationCode). The PalmCode is extracted using the 2-D Gabor filters based algorithm and the OrientationCode is computed using several directional templates. Then several fusion strategies are investigated and compared. The experimental results show that the fusion of the PalmCode and OrientationCode using the Product, Sum and Weighted Sum strategies can greatly improve the accuracy of palmprint authentication, which is up to 99.6%.

  18. Pulsed Power Driven Fusion Energy

    SciTech Connect

    SLUTZ,STEPHEN A.

    1999-11-22

    Pulsed power is a robust and inexpensive technology for obtaining high powers. Considerable progress has been made on developing light ion beams as a means of transporting this power to inertial fusion capsules. However, further progress is hampered by the lack of an adequate ion source. Alternatively, z-pinches can efficiently convert pulsed power into thermal radiation, which can be used to drive an inertial fusion capsule. However, a z-pinch driven fusion explosion will destroy a portion of the transmission line that delivers the electrical power to the z-pinch. They investigate several options for providing standoff for z-pinch driven fusion. Recyclable Transmission Lines (RTLs) appear to be the most promising approach.

  19. Mulitvariate Visualization with Data Fusion

    SciTech Connect

    Wong, Pak C.; Foote, Harlan P.; Kao, David L.; Leung, Lai R.; Thomas, James J.

    2002-12-26

    We discuss a fusion-based visualization method to analyze a 2D flow field together with its related scalars. The primary difference between a conventional visualization and a fusion-based visuali-zation is that the former draws on a single image whereas the latter draws on multiple see-through layers, which are then over-laid on each other to form the final visualization. We propose uniquely designed colormaps to highlight flow features that would not be shown with conventional colormaps. We present fusion techniques that integrate multiple single-purpose flow visualiza-tion techniques into the same viewing space. Our highly flexible fusion approach allows scientists to explore multiple parameters concurrently by mixing and matching images without frequently reconstructing new visualizations from its data for every possible combination. Sample datasets collected from a climate modeling study are used to demonstrate our approach

  20. Mulitvariate Visualization with Data Fusion

    SciTech Connect

    Wong, Pak C.; Foote, Harlan P.; Kao, David L.; Leung, Lai R.; Thomas, James J.

    2002-12-31

    We discuss a fusion-based visualization method to analyze a 2D flow field together with its related scalars. The primary difference between a conventional visualization and a fusion-based visuali-zation is that the former draws on a single image whereas the latter draws on multiple see-through layers, which are then over-laid on each other to form the final visualization. We propose uniquely designed colormaps to highlight flow features that would not be shown with conventional colormaps. We present fusion techniques that integrate multiple single-purpose flow visualiza-tion techniques into the same viewing space. Our highly flexible fusion approach allows scientists to explore multiple parameters concurrently by mixing and matching images without frequently reconstructing new visualizations from its data for every possible combination. Sample datasets collected from a climate modeling study are used to demonstrate our approach

  1. Laser fusion monthly -- August 1980

    SciTech Connect

    Ahlstrom, H.G.

    1980-08-01

    This report documents the monthly progress for the laser fusion research at Lawrence Livermore National Laboratory. First it gives facilities report for both the Shiva and Argus projects. Topics discussed include; laser system for the Nova Project; the fusion experiments analysis facility; optical/x-ray streak camera; Shiva Dante System temporal response; 2{omega}{sub 0} experiment; and planning for an ICF engineering test facility.

  2. Cavitation and Fusion

    NASA Astrophysics Data System (ADS)

    Stringham, Roger S.

    2005-12-01

    Natural cavitation phenomena in D2O using piezo devices, is now amplified initiating DD fusion events that produce heat and helium. The transient cavitation bubble produces micro accelerators in the form of jets containing high densities of deuterons, 1024-25/cc from the cavitating D2O. An electrically driven piezo device in a reactor filled with D2O produces jets that implant deuterons into a target foil producing 4He and T plus heat. There is no long range radiation associated with this process. We are moving in the direction of utilizing smaller systems by gaining faster and less expensive technology growth moving from successes at 0.2 and 0.4 MHz to 1.7 MHz. One of the results of our low frequency studies is a 1 to 3 MHz induced standing wave in our target foils. We are using sonoluminescence intensity as a tool to guide us in finding highest plasma density in the adiabatic bubble collapse process in the jet plasma formation. The generation of these sonoluminescence photons relates to conditions for the target implantation process. These experiments and the analytical methods have concentrated on the mass spectroscopy of reactor gases, calorimetry of the reactor and power supply, and the scanning electron microscope photographs of target foils. This work provides a path for an ecological and hydrocarbon-free energy source for all energy applications.

  3. Image Fusion During Vascular and Nonvascular Image-Guided Procedures☆

    PubMed Central

    Abi-Jaoudeh, Nadine; Kobeiter, Hicham; Xu, Sheng; Wood, Bradford J.

    2013-01-01

    Image fusion may be useful in any procedure where previous imaging such as positron emission tomography, magnetic resonance imaging, or contrast-enhanced computed tomography (CT) defines information that is referenced to the procedural imaging, to the needle or catheter, or to an ultrasound transducer. Fusion of prior and intraoperative imaging provides real-time feedback on tumor location or margin, metabolic activity, device location, or vessel location. Multimodality image fusion in interventional radiology was initially introduced for biopsies and ablations, especially for lesions only seen on arterial phase CT, magnetic resonance imaging, or positron emission tomography/CT but has more recently been applied to other vascular and nonvascular procedures. Two different types of platforms are commonly used for image fusion and navigation: (1) electromagnetic tracking and (2) cone-beam CT. Both technologies would be reviewed as well as their strengths and weaknesses, indications, when to use one vs the other, tips and guidance to streamline use, and early evidence defining clinical benefits of these rapidly evolving, commercially available and emerging techniques. PMID:23993079

  4. Fusion Safety Program annual report, fiscal year 1992

    SciTech Connect

    Holland, D.F.; Cadwallader, L.C.; Herring, J.S.; Longhurst, G.R.; McCarthy, K.A.; Merrill, B.J.; Piet, S.J.

    1993-01-01

    This report summarizes the major activities of the Fusion Safety Program in fiscal year 1992. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory and EG&G Idaho, Inc. is the prime contractor for this program. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL and in participating organizations including the Westinghouse Hanford Company at the Hanford Engineering Development Laboratory, the Massachusetts Institute of Technology, and the University of Wisconsin. The technical areas covered in the report include tritium safety, activation product release, reactions involving beryllium, reactions involving lithium breeding materials, safety of fusion magnet systems, plasma disruptions, risk assessment failure rate data base, and computer code development for reactor transients. Also included in the report is a summary of the safety and environmental studies performed by the INEL for the Tokamak Physics Experiments and the Tokamak Fusion Test Reactor, the safety analysis for the International Thermonuclear Experimental Reactor design, and the technical support for the ARIES commercial reactor design study.

  5. Fusion Safety Program annual report, fiscal year 1992

    SciTech Connect

    Holland, D.F.; Cadwallader, L.C.; Herring, J.S.; Longhurst, G.R.; McCarthy, K.A.; Merrill, B.J.; Piet, S.J.

    1993-01-01

    This report summarizes the major activities of the Fusion Safety Program in fiscal year 1992. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory and EG G Idaho, Inc. is the prime contractor for this program. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL and in participating organizations including the Westinghouse Hanford Company at the Hanford Engineering Development Laboratory, the Massachusetts Institute of Technology, and the University of Wisconsin. The technical areas covered in the report include tritium safety, activation product release, reactions involving beryllium, reactions involving lithium breeding materials, safety of fusion magnet systems, plasma disruptions, risk assessment failure rate data base, and computer code development for reactor transients. Also included in the report is a summary of the safety and environmental studies performed by the INEL for the Tokamak Physics Experiments and the Tokamak Fusion Test Reactor, the safety analysis for the International Thermonuclear Experimental Reactor design, and the technical support for the ARIES commercial reactor design study.

  6. Prospects for Tokamak Fusion Reactors

    SciTech Connect

    Sheffield, J.; Galambos, J.

    1995-04-01

    This paper first reviews briefly the status and plans for research in magnetic fusion energy and discusses the prospects for the tokamak magnetic configuration to be the basis for a fusion power plant. Good progress has been made in achieving fusion reactor-level, deuterium-tritium (D-T) plasmas with the production of significant fusion power in the Joint European Torus (up to 2 MW) and the Tokamak Fusion Test Reactor (up to 10 MW) tokamaks. Advances on the technologies of heating, fueling, diagnostics, and materials supported these achievements. The successes have led to the initiation of the design phases of two tokamaks, the International Thermonuclear Experimental Reactor (ITER) and the US Toroidal Physics Experiment (TPX). ITER will demonstrate the controlled ignition and extended bum of D-T plasmas with steady state as an ultimate goal. ITER will further demonstrate technologies essential to a power plant in an integrated system and perform integrated testing of the high heat flux and nuclear components required to use fusion energy for practical purposes. TPX will complement ITER by testing advanced modes of steady-state plasma operation that, coupled with the developments in ITER, will lead to an optimized demonstration power plant.

  7. TRITIUM ACCOUNTANCY IN FUSION SYSTEMS

    SciTech Connect

    Klein, J. E.; Farmer, D. A.; Moore, M. L.; Tovo, L. L.; Poore, A. S.; Clark, E. A.; Harvel, C. D.

    2014-03-06

    The US Department of Energy (DOE) has clearly defined requirements for nuclear material control and accountability (MC&A) of tritium whereas the International Atomic Energy Agency (IAEA) does not since tritium is not a fissile material. MC&A requirements are expected for tritium fusion machines and will be dictated by the host country or regulatory body where the machine is operated. Material Balance Areas (MBAs) are defined to aid in the tracking and reporting of nuclear material movements and inventories. Material subaccounts (MSAs) are established along with key measurement points (KMPs) to further subdivide a MBA to localize and minimize uncertainties in the inventory difference (ID) calculations for tritium accountancy. Fusion systems try to minimize tritium inventory which may require continuous movement of material through the MSAs. The ability of making meaningful measurements of these material transfers is described in terms of establishing the MSA structure to perform and reconcile ID calculations. For fusion machines, changes to the traditional ID equation will be discussed which includes breading, burn-up, and retention of tritium in the fusion device. The concept of “net” tritium quantities consumed or lost in fusion devices is described in terms of inventory taking strategies and how it is used to track the accumulation of tritium in components or fusion machines.

  8. Tritium accountancy in fusion systems

    SciTech Connect

    Klein, J.E.; Clark, E.A.; Harvel, C.D.; Farmer, D.A.; Tovo, L.L.; Poore, A.S.; Moore, M.L.

    2015-03-15

    The US Department of Energy (DOE) has clearly defined requirements for nuclear material control and accountability (MCA) of tritium whereas the International Atomic Energy Agency (IAEA) does not since tritium is not a fissile material. MCA requirements are expected for tritium fusion machines and will be dictated by the host country or regulatory body where the machine is operated. Material Balance Areas (MBA) are defined to aid in the tracking and reporting of nuclear material movements and inventories. Material sub-accounts (MSA) are established along with key measurement points (KMP) to further subdivide a MBA to localize and minimize uncertainties in the inventory difference (ID) calculations for tritium accountancy. Fusion systems try to minimize tritium inventory which may require continuous movement of material through the MSA. The ability of making meaningful measurements of these material transfers is described in terms of establishing the MSA structure to perform and reconcile ID calculations. For fusion machines, changes to the traditional ID equation will be discussed which includes breeding, burn-up, and retention of tritium in the fusion device. The concept of 'net' tritium quantities consumed or lost in fusion devices is described in terms of inventory taking strategies and how it is used to track the accumulation of tritium in components or fusion machines. (authors)

  9. Commercial cooking equipment improvement

    SciTech Connect

    Himmel, R.L.

    1981-10-01

    A program to improve the efficiency of gas-fired commercial cooking equipment has focused on deep-fat fryers and the oven, open-top, hot-top, and fry-top sections of ranges. A newly developed infrared deep-fat fryer provided to be 25% more efficient than conventional units. Using the direct-fired forced-convection approach in an oven reduced the fuel consumed during baking by 55%. A range open-top burner system with an experimental power burner consumed 33% less fuel and time than conventional models. Preliminary modifications to heavy-duty hot-top and fry-top sections demonstrated fuel savings of 43% and 30%, respectively. More R and D is planned to incorporate manufacturer suggestions resulting in more complete experimental models that will aid in commercializing these improved appliances.

  10. Commercial jet transport crashworthiness

    NASA Technical Reports Server (NTRS)

    Widmayer, E.; Brende, O. B.

    1982-01-01

    The results of a study to identify areas of research and approaches that may result in improved occupant survivability and crashworthiness of transport aircraft are given. The study defines areas of structural crashworthiness for transport aircraft which might form the basis for a research program. A 10-year research and development program to improve the structural impact resistance of general aviation and commercial jet transport aircraft is planned. As part of this program parallel studies were conducted to review the accident experience of commercial transport aircraft, assess the accident performance of structural components and the status of impact resistance technology, and recommend areas of research and development for that 10-year plan. The results of that study are also given.

  11. A need for non-tokamak approaches to magnetic fusion energy

    NASA Astrophysics Data System (ADS)

    Bathke, C. G.; Krakowski, R. A.; Miller, R. L.

    Focusing exclusively on conventional tokamak physics in the quest for commercial fusion power is premature, and the options for both advanced-tokamak and non-tokamak concepts need continued investigation. The basis for this claim is developed, and promising advanced-tokamak and non-tokamak options are suggested.

  12. Commercial Aircraft Development and the Export Market

    NASA Technical Reports Server (NTRS)

    Snodgrass, J.

    1972-01-01

    The various factors which endanger the future of commercial aircraft development are defined. The factors discussed are: (1) a decline in federally funded research and development programs, (2) a general decline in the economic health of the domestic airlines, (3) the increased cost of development which may be several times the net worth of the company, (4) the development overseas of common market and manufacturing consortia, and (5) foreign manufacturers receiving significant financial support from their national governments. It is stated that unless immediate and innovative solutions to combat these factors are found, the commercial aviation industry will be in serious difficulty.

  13. MIL1A

    Atmospheric Science Data Center

    2014-09-03

    ... MISR Level 1A camera charge-coupled device (CCD) Science Data: Reformatted Annotated Level 1A product of the CCD science data. ... Files:  Processing Status Production Report Read Software Files :  Data Product ...

  14. Novel Hydrophobin Fusion Tags for Plant-Produced Fusion Proteins

    PubMed Central

    Ritala, Anneli; Linder, Markus; Joensuu, Jussi

    2016-01-01

    Hydrophobin fusion technology has been applied in the expression of several recombinant proteins in plants. Until now, the technology has relied exclusively on the Trichoderma reesei hydrophobin HFBI. We screened eight novel hydrophobin tags, T. reesei HFBII, HFBIII, HFBIV, HFBV, HFBVI and Fusarium verticillioides derived HYD3, HYD4 and HYD5, for production of fusion proteins in plants and purification by two-phase separation. To study the properties of the hydrophobins, we used N-terminal and C-terminal GFP as a fusion partner. Transient expression of the hydrophobin fusions in Nicotiana benthamiana revealed large variability in accumulation levels, which was also reflected in formation of protein bodies. In two-phase separations, only HFBII and HFBIV were able to concentrate GFP into the surfactant phase from a plant extract. The separation efficiency of both tags was comparable to HFBI. When the accumulation was tested side by side, HFBII-GFP gave a better yield than HFBI-GFP, while the yield of HFBIV-GFP remained lower. Thus we present here two alternatives for HFBI as functional fusion tags for plant-based protein production and first step purification. PMID:27706254

  15. SKIDS data fusion project

    NASA Astrophysics Data System (ADS)

    Greenway, Phil

    1992-04-01

    The European Community's strategic research initiative in information technology (ESPRIT) has been in place for nearly five years. An early example of the pan-European collaborative projects being conducted under this initiative is 'SKIDS': Signal and Knowledge Integration with Decisional Control for Multisensory Systems. This four year project, which is approaching completion, aims to build a real-time multisensor perception machine. This machine will be capable of performing data fusion, interpretation, situation assessment, and resource allocation tasks, under the constraints of both time and resource availability, and in the presence of uncertain data. Of the many possible applications, the surveillance and monitoring of a semi-automated 'factory environment' has been chosen as a challenging and representative test scenario. This paper presents an overview of the goals and objectives of the project, the makeup of the consortium, and roles of the members within it, and the main technical achievements to data. In particular, the following are discussed: relevant application domains, and the generic requirements that can be inferred from them; sensor configuration, including choice, placement, etc.; control paradigms, including the possible trade-offs between centralized, hierarchical, and decentralized approaches; the corresponding hardware architectural choices, including the need for parallel processing; and the appropriate software architecture and infra-structure required to support the chosen task oriented approach. Specific attention is paid to the functional decomposition of the system and how the requirements for control impact the organization of the identified interpretation tasks. Future work and outstanding problems are considered in some concluding remarks. By virtue of limited space, this paper is descriptive rather than explanatory.

  16. Designing Image Operators for MRI-PET Image Fusion of the Brain

    SciTech Connect

    Marquez, Jorge; Gastelum, Alfonso; Padilla, Miguel A.

    2006-09-08

    Our goal is to obtain images combining in a useful and precise way the information from 3D volumes of medical imaging sets. We address two modalities combining anatomy (Magnetic Resonance Imaging or MRI) and functional information (Positron Emission Tomography or PET). Commercial imaging software offers image fusion tools based on fixed blending or color-channel combination of two modalities, and color Look-Up Tables (LUTs), without considering the anatomical and functional character of the image features. We used a sensible approach for image fusion taking advantage mainly from the HSL (Hue, Saturation and Luminosity) color space, in order to enhance the fusion results. We further tested operators for gradient and contour extraction to enhance anatomical details, plus other spatial-domain filters for functional features corresponding to wide point-spread-function responses in PET images. A set of image-fusion operators was formulated and tested on PET and MRI acquisitions.

  17. Designing Image Operators for MRI-PET Image Fusion of the Brain

    NASA Astrophysics Data System (ADS)

    Márquez, Jorge; Gastélum, Alfonso; Padilla, Miguel A.

    2006-09-01

    Our goal is to obtain images combining in a useful and precise way the information from 3D volumes of medical imaging sets. We address two modalities combining anatomy (Magnetic Resonance Imaging or MRI) and functional information (Positron Emission Tomography or PET). Commercial imaging software offers image fusion tools based on fixed blending or color-channel combination of two modalities, and color Look-Up Tables (LUTs), without considering the anatomical and functional character of the image features. We used a sensible approach for image fusion taking advantage mainly from the HSL (Hue, Saturation and Luminosity) color space, in order to enhance the fusion results. We further tested operators for gradient and contour extraction to enhance anatomical details, plus other spatial-domain filters for functional features corresponding to wide point-spread-function responses in PET images. A set of image-fusion operators was formulated and tested on PET and MRI acquisitions.

  18. IEC fusion: The future power and propulsion system for space

    NASA Astrophysics Data System (ADS)

    Hammond, Walter E.; Coventry, Matt; Hanson, John; Hrbud, Ivana; Miley, George H.; Nadler, Jon

    2000-01-01

    Rapid access to any point in the solar system requires advanced propulsion concepts that will provide extremely high specific impulse, low specific power, and a high thrust-to-power ratio. Inertial Electrostatic Confinement (IEC) fusion is one of many exciting concepts emerging through propulsion and power research in laboratories across the nation which will determine the future direction of space exploration. This is part of a series of papers that discuss different applications of the Inertial Electrostatic Confinement (IEC) fusion concept for both in-space and terrestrial use. IEC will enable tremendous advances in faster travel times within the solar system. The technology is currently under investigation for proof of concept and transitioning into the first prototype units for commercial applications. In addition to use in propulsion for space applications, terrestrial applications include desalinization plants, high energy neutron sources for radioisotope generation, high flux sources for medical applications, proton sources for specialized medical applications, and tritium production. .

  19. Fusion Plasma Theory project summaries

    SciTech Connect

    Not Available

    1993-10-01

    This Project Summary book is a published compilation consisting of short descriptions of each project supported by the Fusion Plasma Theory and Computing Group of the Advanced Physics and Technology Division of the Department of Energy, Office of Fusion Energy. The summaries contained in this volume were written by the individual contractors with minimal editing by the Office of Fusion Energy. Previous summaries were published in February of 1982 and December of 1987. The Plasma Theory program is responsible for the development of concepts and models that describe and predict the behavior of a magnetically confined plasma. Emphasis is given to the modelling and understanding of the processes controlling transport of energy and particles in a toroidal plasma and supporting the design of the International Thermonuclear Experimental Reactor (ITER). A tokamak transport initiative was begun in 1989 to improve understanding of how energy and particles are lost from the plasma by mechanisms that transport them across field lines. The Plasma Theory program has actively-participated in this initiative. Recently, increased attention has been given to issues of importance to the proposed Tokamak Physics Experiment (TPX). Particular attention has been paid to containment and thermalization of fast alpha particles produced in a burning fusion plasma as well as control of sawteeth, current drive, impurity control, and design of improved auxiliary heating. In addition, general models of plasma behavior are developed from physics features common to different confinement geometries. This work uses both analytical and numerical techniques. The Fusion Theory program supports research projects at US government laboratories, universities and industrial contractors. Its support of theoretical work at universities contributes to the office of Fusion Energy mission of training scientific manpower for the US Fusion Energy Program.

  20. Kinetic advantage of controlled intermediate nuclear fusion

    SciTech Connect

    Guo Xiaoming

    2012-09-26

    The dominated process of controlled fusion is to let nuclei gain enough kinetic energy to overcome Coulomb barrier. As a result, a fusion scheme can consider two factors in its design: to increase kinetic energy of nuclei and to alter the Coulomb barrier. Cold Fusion and Hot fusion are all one-factor schemes while Intermediate Fusion is a twofactors scheme. This made CINF kinetically superior. Cold Fusion reduces deuteron-deuteron distance, addressing Coulomb barrier, and Hot Fusion heat up plasma into extreme high temperature, addressing kinetic energy. Without enough kinetic energy made Cold Fusion skeptical. Extreme high temperature made Hot Fusion very difficult to engineer. Because CIFN addresses both factors, CIFN is a more promising technique to be industrialized.

  1. Kinetic advantage of controlled intermediate nuclear fusion

    NASA Astrophysics Data System (ADS)

    Guo, Xiaoming

    2012-09-01

    The dominated process of controlled fusion is to let nuclei gain enough kinetic energy to overcome Coulomb barrier. As a result, a fusion scheme can consider two factors in its design: to increase kinetic energy of nuclei and to alter the Coulomb barrier. Cold Fusion and Hot fusion are all one-factor schemes while Intermediate Fusion is a twofactors scheme. This made CINF kinetically superior. Cold Fusion reduces deuteron-deuteron distance, addressing Coulomb barrier, and Hot Fusion heat up plasma into extreme high temperature, addressing kinetic energy. Without enough kinetic energy made Cold Fusion skeptical. Extreme high temperature made Hot Fusion very difficult to engineer. Because CIFN addresses both factors, CIFN is a more promising technique to be industrialized.

  2. Accelerators for Fusion Materials Testing

    NASA Astrophysics Data System (ADS)

    Knaster, Juan; Okumura, Yoshikazu

    Fusion materials research is a worldwide endeavor as old as the parallel one working toward the long term stable confinement of ignited plasma. In a fusion reactor, the preservation of the required minimum thermomechanical properties of the in-vessel components exposed to the severe irradiation and heat flux conditions is an indispensable factor for safe operation; it is also an essential goal for the economic viability of fusion. Energy from fusion power will be extracted from the 14 MeV neutron freed as a product of the deuterium-tritium fusion reactions; thus, this kinetic energy must be absorbed and efficiently evacuated and electricity eventually generated by the conventional methods of a thermal power plant. Worldwide technological efforts to understand the degradation of materials exposed to 14 MeV neutron fluxes > 1018 m-2s-1, as expected in future fusion power plants, have been intense over the last four decades. Existing neutron sources can reach suitable dpa ("displacement-per-atom", the figure of merit to assess materials degradation from being exposed to neutron irradiation), but the differences in the neutron spectrum of fission reactors and spallation sources do not allow one to unravel the physics and to anticipate the degradation of materials exposed to fusion neutrons. Fusion irradiation conditions can be achieved through Li (d, xn) nuclear reactions with suitable deuteron beam current and energy, and an adequate flowing lithium screen. This idea triggered in the late 1970s at Los Alamos National Laboratory (LANL) a campaign working toward the feasibility of continuous wave (CW) high current linacs framed by the Fusion Materials Irradiation Test (FMIT) project. These efforts continued with the Low Energy Demonstrating Accelerator (LEDA) (a validating prototype of the canceled Accelerator Production of Tritium (APT) project), which was proposed in 2002 to the fusion community as a 6.7MeV, 100mA CW beam injector for a Li (d, xn) source to bridge

  3. Accelerators for Fusion Materials Testing

    NASA Astrophysics Data System (ADS)

    Knaster, Juan; Okumura, Yoshikazu

    Fusion materials research is a worldwide endeavor as old as the parallel one working toward the long term stable confinement of ignited plasma. In a fusion reactor, the preservation of the required minimum thermomechanical properties of the in-vessel components exposed to the severe irradiation and heat flux conditions is an indispensable factor for safe operation; it is also an essential goal for the economic viability of fusion. Energy from fusion power will be extracted from the 14 MeV neutron freed as a product of the deuterium-tritium fusion reactions; thus, this kinetic energy must be absorbed and efficiently evacuated and electricity eventually generated by the conventional methods of a thermal power plant. Worldwide technological efforts to understand the degradation of materials exposed to 14 MeV neutron fluxes >1018 m-2s-1, as expected in future fusion power plants, have been intense over the last four decades. Existing neutron sources can reach suitable dpa (“displacement-per-atom”, the figure of merit to assess materials degradation from being exposed to neutron irradiation), but the differences in the neutron spectrum of fission reactors and spallation sources do not allow one to unravel the physics and to anticipate the degradation of materials exposed to fusion neutrons. Fusion irradiation conditions can be achieved through Li (d, xn) nuclear reactions with suitable deuteron beam current and energy, and an adequate flowing lithium screen. This idea triggered in the late 1970s at Los Alamos National Laboratory (LANL) a campaign working toward the feasibility of continuous wave (CW) high current linacs framed by the Fusion Materials Irradiation Test (FMIT) project. These efforts continued with the Low Energy Demonstrating Accelerator (LEDA) (a validating prototype of the canceled Accelerator Production of Tritium (APT) project), which was proposed in 2002 to the fusion community as a 6.7MeV, 100mA CW beam injector for a Li (d, xn) source to bridge

  4. Object recognition by active fusion

    NASA Astrophysics Data System (ADS)

    Prantl, Manfred; Kopp-Borotschnig, Hermann; Ganster, Harald; Sinclair, David; Pinz, Axel J.

    1996-10-01

    Today's computer vision applications often have to deal with multiple, uncertain, and incomplete visual information. In this paper, we apply a new method, termed 'active fusion', to the problem of generic object recognition. Active fusion provides a common framework for active selection and combination of information from multiple sources in order to arrive at a reliable result at reasonable costs. In our experimental setup we use a camera mounted on a 2m by 1.5m x/z-table observing objects placed on a rotating table. Zoom, pan, tilt, and aperture setting of the camera can be controlled by the system. We follow a part-based approach, trying to decompose objects into parts, which are modeled as geons. The active fusion system starts from an initial view of the objects placed on the table and is continuously trying to refine its current object hypotheses by requesting additional views. The implementation of active fusion on the basis of probability theory, Dempster-Shafer's theory of evidence and fuzzy set theory is discussed. First results demonstrating segmentation improvements by active fusion are presented.

  5. A Model for Membrane Fusion

    NASA Astrophysics Data System (ADS)

    Ngatchou, Annita

    2010-01-01

    Pheochromocytoma is a tumor of the adrenal gland which originates from chromaffin cells and is characterized by the secretion of excessive amounts of neurotransmitter which lead to high blood pressure and palpitations. Pheochromocytoma contain membrane bound granules that store neurotransmitter. The release of these stored molecules into the extracellular space occurs by fusion of the granule membrane with the cell plasma membrane, a process called exocytosis. The molecular mechanism of this membrane fusion is not well understood. It is proposed that the so called SNARE proteins [1] are the pillar of vesicle fusion as their cleavage by clostridial toxin notably, Botulinum neurotoxin and Tetanus toxin abrogate the secretion of neurotransmitter [2]. Here, I describe how physical principles are applied to a biological cell to explore the role of the vesicle SNARE protein synaptobrevin-2 in easing granule fusion. The data presented here suggest a paradigm according to which the movement of the C-terminal of synaptobrevin-2 disrupts the lipid bilayer to form a fusion pore through which molecules can exit.

  6. Fusion genes in solid tumors.

    PubMed

    Aman, P

    1999-08-01

    Tumor development in different cell types and tissue locations involves many pathways, distinct genes and exogenous factors. Tumor type-specific chromosome rearrangements resulting in fusion genes or promoter swapping are believed to be involved in the early development of many tumor types. They are present in almost all cases of a particular tumor type and cases have been described that carry only tumor type-specific translocations without any signs of other cytogenetic changes. The mechanisms behind chromosome rearrangements in solid tumors are largely unknown. Radiation is an important factor in thyroid carcinomas but no com-$bmon sequence motifs are made out in the break points of solid tumors. The fusion genes found in sarcomas are dominated by the transcription factor type of genes with the TLS/FUS and EWS series of fusion genes as the largest group. More than 50% of papillary thyroid carcinomas carry fusion proteins with tyrosine kinase activity. Rearrangements involving HMGIC, HMGIY, and PLAG1 are common in benign mesenchymal tumors and salivary gland adenomas. Many recurrent tumor translocations show a strict specificity for tumor type. This specificity can most likely be explained by the specific sets of target genes that are deregulated by the fusion gene products. Identification of the downstream target genes is currently the object of intense research and may provide us with information that will help design better diagnostic tools and eventually find a cure for these diseases.

  7. Analyses in support of the Laboratory Microfusion Facility and ICF commercial reactor designs

    SciTech Connect

    Meier, W.R.; Monsler, M.J.

    1988-12-28

    Our work on this contract was divided into two major categories; two thirds of the total effort was in support of the Laboratory Microfusion Facility (LMF), and one third of the effort was in support of Inertial Confinement Fusion (ICF) commercial reactors. This final report includes copies of the formal reports, memoranda, and viewgraph presentations that were completed under this contract.

  8. Hot fusion or cold fusion, best route to the SHEs?

    NASA Astrophysics Data System (ADS)

    Loveland, Walter

    2010-02-01

    Elements 102-113 have been synthesized using cold fusion reactions (Pb or Bi target nuclei, massive projectiles., E*=13 MeV, high survival probabilities,significant fusion hindrance). The production cross sections decrease with increasing ZCN with a cross section of 27 fb being measured for element 113. Synthesis of elements 102-108 by hot fusion reactions (actinide target nuclei, intermediate mass projectiles, E*=30-50 MeV, low survival probability, small fusion hindrance) shows decreasing production cross sections for Z=102 to Z=108 and then the cross sections level out at a few pb out to Z=118. Upper limit cross sections for the production of Z=120 nuclei in hot fusion reactions are ˜ 0.1 pb. How should one go forward to make nuclei with Z > 120 or with large neutron numbers, N ˜ 184? The cross section for the production of an evaporation residue, σEVR, is σEVR=σCNWsur where σCN is the complete fusion cross section and Wsur is the survival probability of the completely fused system. The complete fusion cross section can be written as σCN=∑J=0^J σcapture (Ec.m.,J)PCN( Ec.m.,J) where σcapture(Ec.m.,J) is the capture cross section and PCN is the probability that the projectile-target system will evolve inside the fission saddle point to form a completely fused system rather than reseparating (quasifission). I have used this formalism to make estimates of the best reactions to make new heavy nuclei using stable and radioactive beams. I conclude that stable beams offer the best opportunities to make new chemical elements and that radioactive beams offer new opportunities to make nuclei to study the atomic physics and chemistry of the heaviest elements. The radioactive beam reactions involve the light neutron-rich projectiles interacting in hot fusion reactions. If time permits I will also discuss recent experiments to make heavy nuclei using multi-nucleon transfer reactions. )

  9. Accelerating Commercial Remote Sensing

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Through the Visiting Investigator Program (VIP) at Stennis Space Center, Community Coffee was able to use satellites to forecast coffee crops in Guatemala. Using satellite imagery, the company can produce detailed maps that separate coffee cropland from wild vegetation and show information on the health of specific crops. The data can control coffee prices and eventually may be used to optimize application of fertilizers, pesticides and irrigation. This would result in maximal crop yields, minimal pollution and lower production costs. VIP is a mechanism involving NASA funding designed to accelerate the growth of commercial remote sensing by promoting general awareness and basic training in the technology.

  10. Commercialization Assistance Program

    SciTech Connect

    Jenny C Servo, Ph D

    2008-02-15

    The Commercialization Assistance Program (CAP) is offered to Phase II awardees of the Department of Energy's Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The purpose of this program is to increase both the likelihood and speed of technology transition to Phase III of technologies which DOE has funded. This program has been offered to DOE SBIR firms since 1990 and has resulted in significant and well documented return on investment. This final report decribes the results of the CAP that was offered to participants during the last cycle.

  11. Present status of liquid metal research for a fusion reactor

    NASA Astrophysics Data System (ADS)

    Tabarés, Francisco L.

    2016-01-01

    Although the use of solid materials as targets of divertor plasmas in magnetic fusion research is accepted as the standard solution for the very challenging issue of power and particle handling in a fusion reactor, a generalized feeling that the present options chosen for ITER will not represent the best choice for a reactor is growing up. The problems found for tungsten, the present selection for the divertor target of ITER, in laboratory tests and in hot plasma fusion devices suggest so. Even in the absence of the strong neutron irradiation expected in a reactor, issues like surface melting, droplet ejection, surface cracking, dust generation, etc., call for alternative solutions in a long pulse, high efficient fusion energy-producing continuous machine. Fortunately enough, decades of research on plasma facing materials based on liquid metals (LMs) have produced a wealth of appealing ideas that could find practical application in the route to the realization of a commercial fusion power plant. The options presently available, although in a different degree of maturity, range from full coverage of the inner wall of the device with liquid metals, so that power and particle exhaust together with neutron shielding could be provided, to more conservative combinations of liquid metal films and conventional solid targets basically representing a sort of high performance, evaporative coating for the alleviation of the surface degradation issues found so far. In this work, an updated review of worldwide activities on LM research is presented, together with some open issues still remaining and some proposals based on simple physical considerations leading to the optimization of the most conservative alternatives.

  12. Accelerating advanced-materials commercialization

    NASA Astrophysics Data System (ADS)

    Maine, Elicia; Seegopaul, Purnesh

    2016-05-01

    Long commercialization times, high capital costs and sustained uncertainty deter investment in innovation for advanced materials. With appropriate strategies, technology and market uncertainties can be reduced, and the commercialization of advanced materials accelerated.

  13. Overview of Commercial Buildings, 2003

    EIA Publications

    2008-01-01

    The Energy Information Administration conducts the Commercial Buildings Energy Consumption Survey (CBECS) to collect information on energy-related building characteristics and types and amounts of energy consumed in commercial buildings in the United States.

  14. (Meeting on fusion reactor materials)

    SciTech Connect

    Jones, R.H. ); Klueh, R.L.; Rowcliffe, A.F.; Wiffen, F.W. ); Loomis, B.A. )

    1990-11-01

    During his visit to the KfK, Karlsruhe, F. W. Wiffen attended the IEA 12th Working Group Meeting on Fusion Reactor Materials. Plans were made for a low-activation materials workshop at Culham, UK, for April 1991, a data base workshop in Europe for June 1991, and a molecular dynamics workshop in the United States in 1991. At the 11th IEA Executive Committee on Fusion Materials, discussions centered on the recent FPAC and Colombo panel review in the United States and EC, respectively. The Committee also reviewed recent progress toward a neutron source in the United States (CWDD) and in Japan (ESNIT). A meeting with D. R. Harries (consultant to J. Darvas) yielded a useful overview of the EC technology program for fusion. Of particular interest to the US program is a strong effort on a conventional ferritic/martensitic steel for fist wall/blanket operation beyond NET/ITER.

  15. Bioenergetic roles of mitochondrial fusion.

    PubMed

    Silva Ramos, Eduardo; Larsson, Nils-Göran; Mourier, Arnaud

    2016-08-01

    Mitochondria are bioenergetic hotspots, producing the bulk of ATP by the oxidative phosphorylation process. Mitochondria are also structurally dynamic and undergo coordinated fusion and fission to maintain their function. Recent studies of the mitochondrial fusion machinery have provided new evidence in detailing their role in mitochondrial metabolism. Remarkably, mitofusin 2, in addition to its role in fusion, is important for maintaining coenzyme Q levels and may be an integral player in the mevalonate synthesis pathway. Here, we review the bioenergetic roles of mitochondrial dynamics and emphasize the importance of the in vitro growth conditions when evaluating mitochondrial respiration. This article is part of a Special Issue entitled 'EBEC 2016: 19th European Bioenergetics Conference, Riva del Garda, Italy, July 2-6, 2016,' edited by Prof. Paolo Bernardi. PMID:27060252

  16. Superconducting magnets for fusion applications

    SciTech Connect

    Henning, C.D.

    1987-07-02

    Fusion magnet technology has made spectacular advances in the past decade; to wit, the Mirror Fusion Test Facility and the Large Coil Project. However, further advances are still required for advanced economical fusion reactors. Higher fields to 14 T and radiation-hardened superconductors and insulators will be necessary. Coupled with high rates of nuclear heating and pulsed losses, the next-generation magnets will need still higher current density, better stability and quench protection. Cable-in-conduit conductors coupled with polyimide insulations and better steels seem to be the appropriate path. Neutron fluences up to 10/sup 19/ neutrons/cm/sup 2/ in niobium tin are achievable. In the future, other amorphous superconductors could raise these limits further to extend reactor life or decrease the neutron shielding and corresponding reactor size.

  17. Fusion Blanket Development in FDF

    NASA Astrophysics Data System (ADS)

    Wong, C. P. C.; Smith, J. P.; Stambaugh, R. D.

    2008-11-01

    To satisfy the electricity and tritium self-sufficiency missions of a Fusion Development Facility (FDF), suitable blanket designs will need to be evaluated, selected and developed. To demonstrate closure of the fusion fuel cycle, 2-3 main tritium breeding blankets will be used to cover most of the available chamber surface area in order to reach the project goal of achieving a tritium breeding ratio, TBR > 1. To demonstrate the feasibility of electricity and tritium production for subsequent devices such as the fusion demonstration power reactor (DEMO), several advanced test blankets will need to be selected and tested on the FDF to demonstrate high coolant outlet temperature necessary for efficient electricity production. Since the design goals for the main and test blankets are different, the design criteria of these blankets will also be different. The considerations in performing the evaluation of blanket and structural material options in concert with the maintenance approach for the FDF will be reported in this paper.

  18. Congress turns cold on fusion

    SciTech Connect

    Marshall, E.

    1984-06-22

    A 5% cut in fusion research budgets will force some programs to be dropped in order to keep the large machinery running unless US and European scientists collaborate instead of competing. Legislators became uneasy about the escalating costs of the new devices. The 1984 budget of $470 million for magnetic fusion research is only half the projected cost of the Tokomak Fusion Core Experiment (TFCX) planned to ignite, for the first time, a self-sustaining burn. Planning for the TCFX continued despite the message from Congress. Work at the large institutions at Princeton, MIT, etc. may survive at the expense of other programs, some of which will lose academic programs as well. Scientists point to the loss of new ideas and approaches when projects are cancelled. Enthusiasm is growing for international collaboration.

  19. Laser fusion experiments at LLL

    SciTech Connect

    Ahlstrom, H.G.

    1980-06-16

    These notes present the experimental basis and status for laser fusion as developed at LLL. Two other chapters, one authored by K.A. Brueckner and the other by C. Max, present the theoretical implosion physics and laser plasma interaction physics. The notes consist of six sections. The first is an introductory section which provides some of the history of inertial fusion and a simple explanation of the concepts involved. The second section presents an extensive discussion of diagnostic instrumentation used in the LLL Laser Fusion Program. The third section is a presentation of laser facilities and capabilities at LLL. The purpose here is to define capability, not to derive how it was obtained. The fourth and fifth sections present the experimental data on laser-plasma interaction and implosion physics. The last chapter is a short projection of the future.

  20. Tissue fusion over nonadhering surfaces

    PubMed Central

    Nier, Vincent; Deforet, Maxime; Duclos, Guillaume; Yevick, Hannah G.; Cochet-Escartin, Olivier; Marcq, Philippe; Silberzan, Pascal

    2015-01-01

    Tissue fusion eliminates physical voids in a tissue to form a continuous structure and is central to many processes in development and repair. Fusion events in vivo, particularly in embryonic development, often involve the purse-string contraction of a pluricellular actomyosin cable at the free edge. However, in vitro, adhesion of the cells to their substrate favors a closure mechanism mediated by lamellipodial protrusions, which has prevented a systematic study of the purse-string mechanism. Here, we show that monolayers can cover well-controlled mesoscopic nonadherent areas much larger than a cell size by purse-string closure and that active epithelial fluctuations are required for this process. We have formulated a simple stochastic model that includes purse-string contractility, tissue fluctuations, and effective friction to qualitatively and quantitatively account for the dynamics of closure. Our data suggest that, in vivo, tissue fusion adapts to the local environment by coordinating lamellipodial protrusions and purse-string contractions. PMID:26199417

  1. MPRS (URBOT) commercialization

    NASA Astrophysics Data System (ADS)

    Ciccimaro, Donny; Baker, William; Hamilton, Ian; Heikkila, Leif; Renick, Joel

    2003-09-01

    The Man Portable Robotic System (MPRS) project objective was to build and deliver hardened robotic systems to the U.S. Army"s 10 Mountain Division in Fort Drum, New York. The system, specifically designed for tunnel and sewer reconnaissance, was equipped with visual and audio sensors that allowed the Army engineers to detect trip wires and booby traps before personnel entered a potentially hostile environment. The MPRS system has shown to be useful in government and military supported field exercises, but the system has yet to reach the hands of civilian users. Potential users in Law Enforcement and Border Patrol have shown a strong interest in the system, but robotic costs were thought to be prohibitive for law enforcement budgets. Through the Center for Commercialization of Advanced Technology (CCAT) program, an attempt will be made to commercialize the MPRS. This included a detailed market analysis performed to verify the market viability of the technologies. Hence, the first step in this phase is to fully define the marketability of proposed technologies in terms of actual market size, pricing and cost factors, competitive risks and/or advantages, and other key factors used to develop marketing and business plans.

  2. Commercial nuclear power 1990

    SciTech Connect

    Not Available

    1990-09-28

    This report presents the status at the end of 1989 and the outlook for commercial nuclear capacity and generation for all countries in the world with free market economies (FME). The report provides documentation of the US nuclear capacity and generation projections through 2030. The long-term projections of US nuclear capacity and generation are provided to the US Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) for use in estimating nuclear waste fund revenues and to aid in planning the disposal of nuclear waste. These projections also support the Energy Information Administration's annual report, Domestic Uranium Mining and Milling Industry: Viability Assessment, and are provided to the Organization for Economic Cooperation and Development. The foreign nuclear capacity projections are used by the DOE uranium enrichment program in assessing potential markets for future enrichment contracts. The two major sections of this report discuss US and foreign commercial nuclear power. The US section (Chapters 2 and 3) deals with (1) the status of nuclear power as of the end of 1989; (2) projections of nuclear capacity and generation at 5-year intervals from 1990 through 2030; and (3) a discussion of institutional and technical issues that affect nuclear power. The nuclear capacity projections are discussed in terms of two projection periods: the intermediate term through 2010 and the long term through 2030. A No New Orders case is presented for each of the projection periods, as well as Lower Reference and Upper Reference cases. 5 figs., 30 tabs.

  3. Commercial Driver Medical Examinations

    PubMed Central

    Moffitt, Gary; Hanowski, Richard J.; Kales, Stefanos N.; Porter, Richard J.; Hegmann, Kurt T.

    2015-01-01

    Objective: The objective of this study was to assess relationships between body mass index (BMI) and comorbid conditions within a large sample of truck drivers. Methods: Commercial driver medical examination data from 88,246 commercial drivers between 2005 and 2012 were analyzed for associations between BMI, medical disorders, and driver certification. Results: Most drivers were obese (53.3%, BMI >30.0 kg/m2) and morbidly obese (26.6%, BMI >35.0 kg/m2), higher than prior reports. Obese drivers were less likely to be certified for 2 years and more likely to report heart disease, hypertension, diabetes mellitus, nervous disorders, sleep disorders, and chronic low back pain (all P < 0.0001). There are relationships between multiple potentially disqualifying conditions and increasing obesity (P < 0.0001). Morbid obesity prevalence increased 8.9% and prevalence of three or more multiple conditions increased fourfold between 2005 and 2012. Conclusions: Obesity is related to multiple medical factors as well as increasing numbers of conditions that limit driving certification. PMID:25710607

  4. Aerocapacitor commercialization plan

    SciTech Connect

    1995-09-12

    The purpose of the Power-One Aerocapacitor Commercialization Plan is to communicate to members of management and to all employees the overall objectives of the corporation. Power-One, Inc., has participated in a US Federal Government Technology Reinvestment Project (TRP), entitled {open_quotes}Advanced Power Conversion based on the Aerocapacitor{close_quotes}: the project is a group effort, with Lawrence Livermore National Labs, GenCorp/Aerojet, PolyStor Corp. (a start-up company), and Power-One forming the consortium. The expected resulting technology is the {open_quotes}Aerocapacitor{close_quotes}, which possesses much higher performance levels than the usual capacitors on the market today. Power-One hopes to incorporate the Aerocapacitor into some of its products, hence enhancing their performance, as well as market privately-labeled aerocapacitors through its distribution channels. This document describes the details of Power-One`s plan to bring to market and commercialize the Aerocapacitor and Aerocapacitor-based products. This plan was formulated while Power-One was part of the Oerocap project. It has since pulled out of this project. What is presented in this plan is the work which was developed prior to the business decision to terminate this work.

  5. Method for vacuum fusion bonding

    DOEpatents

    Ackler, Harold D.; Swierkowski, Stefan P.; Tarte, Lisa A.; Hicks, Randall K.

    2001-01-01

    An improved vacuum fusion bonding structure and process for aligned bonding of large area glass plates, patterned with microchannels and access holes and slots, for elevated glass fusion temperatures. Vacuum pumpout of all components is through the bottom platform which yields an untouched, defect free top surface which greatly improves optical access through this smooth surface. Also, a completely non-adherent interlayer, such as graphite, with alignment and location features is located between the main steel platform and the glass plate pair, which makes large improvements in quality, yield, and ease of use, and enables aligned bonding of very large glass structures.

  6. Plasma physics goes beyond fusion

    NASA Astrophysics Data System (ADS)

    Franklin, Raoul

    2008-11-01

    I was interested to read the fusion supplement published with the October issue of Physics World. However, in asserting that fusion created the need to recognize plasma physics as a separate branch of the subject, Stephen Cowley, the new director of the United Kingdom Atomic Energy Authority, was not quite correct. In fact, the word "plasma" was appropriated from the Greek by the chemical physicist (and later Nobel laureate) Irving Langmuir in 1928. It was used to describe the positive column of a gas discharge, which was then the subject of research into better lighting sources and advertising displays, as well as the underlying science.

  7. Electromagnetic computations for fusion devices

    SciTech Connect

    Turner, L.R.

    1989-09-01

    Among the difficulties in making nuclear fusion a useful energy source, two important ones are producing the magnetic fields needed to drive and confine the plasma, and controlling the eddy currents induced in electrically conducting components by changing fields. All over the world, researchers are developing electromagnetic codes and employing them to compute electromagnetic effects. Ferromagnetic components of a fusion reactor introduce field distortions. Eddy currents are induced in the vacuum vessel, blanket and other torus components of a tokamak when the plasma current disrupts. These eddy currents lead to large forces, and 3-D codes are being developed to study the currents and forces. 35 refs., 6 figs.

  8. Z-Pinch Fusion Propulsion

    NASA Technical Reports Server (NTRS)

    Miernik, Janie

    2011-01-01

    Fusion-based nuclear propulsion has the potential to enable fast interplanetary transportation. Shorter trips are better for humans in the harmful radiation environment of deep space. Nuclear propulsion and power plants can enable high Ispand payload mass fractions because they require less fuel mass. Fusion energy research has characterized the Z-Pinch dense plasma focus method. (1) Lightning is form of pinched plasma electrical discharge phenomena. (2) Wire array Z-Pinch experiments are commonly studied and nuclear power plant configurations have been proposed. (3) Used in the field of Nuclear Weapons Effects (NWE) testing in the defense industry, nuclear weapon x-rays are simulated through Z-Pinch phenomena.

  9. Fusion bonding and alignment fixture

    DOEpatents

    Ackler, Harold D.; Swierkowski, Stefan P.; Tarte, Lisa A.; Hicks, Randall K.

    2000-01-01

    An improved vacuum fusion bonding structure and process for aligned bonding of large area glass plates, patterned with microchannels and access holes and slots, for elevated glass fusion temperatures. Vacuum pumpout of all the components is through the bottom platform which yields an untouched, defect free top surface which greatly improves optical access through this smooth surface. Also, a completely non-adherent interlayer, such as graphite, with alignment and location features is located between the main steel platform and the glass plate pair, which makes large improvements in quality, yield, and ease of use, and enables aligned bonding of very large glass structures.

  10. Fusion Breeder Program interim report

    SciTech Connect

    Moir, R.; Lee, J.D.; Neef, W.

    1982-06-11

    This interim report for the FY82 Fusion Breeder Program covers work performed during the scoping phase of the study, December, 1981-February 1982. The goals for the FY82 study are the identification and development of a reference blanket concept using the fission suppression concept and the definition of a development plan to further the fusion breeder application. The context of the study is the tandem mirror reactor, but emphasis is placed upon blanket engineering. A tokamak driver and blanket concept will be selected and studied in more detail during FY83.

  11. Calculation of fusion product angular correlation coefficients for fusion plasmas

    SciTech Connect

    Murphy, T.J.

    1987-08-01

    The angular correlation coefficients for fusion products are calculated in the cases of Maxwellian and beam-target plasmas. Measurement of these coefficients as a localized ion temperature or fast-ion diagnostic is discussed. 8 refs., 7 figs., 1 tab.

  12. Equivalence of measurement space solution data fusion and complete fusion

    NASA Astrophysics Data System (ADS)

    Ceccherini, Simone

    2016-10-01

    Many observation systems are operating on space-borne and airborne platforms, as well as from ground-based stations, providing measurements of vertical profiles of atmospheric parameters. When independent measurements of the same profile are available data fusion methods can be used to combine them and exploit all the available information for a more comprehensive and accurate description of the atmospheric state. Several data fusion methods can be used. Among the others, both the measurement space solution data fusion method and the complete fusion method have the remarkable properties of using all the acquired information and of providing results that are independent from a priori information used in the individual retrievals. For this reason, though the two methods use two completely different procedures, it is reasonable to expect that they give the same results and in this paper the rigorous proof of the equivalence of the two methods is given. Therefore, the choice between them is only driven by the advantages of the different implementations.

  13. The commercialization of migration.

    PubMed

    Abrera-mangahas, M A

    1989-01-01

    International migration is not new to the Philippines. In the recent outflow of contract workers to the Middle East, there is a shift from individual and family initiated migrations to the more organized, highly commercial variety. While profit-taking intermediaries have played some role in the past, the increase in the number and influence of these intermediaries has altered the story of migration decision-making. In 1975, the signing of the bilateral labor agreement between the governments of Iran and the Philippines signalled the rising demand for Filipino contract workers. From 1970 to 1975, the number of Asian migrant workers in the Gulf countries rose from about 120,000 to 370,000. These figures rose dramatically to 3.3 million in 1985. The growing share of organized and commercialized migration has altered migration decision making. Primarily, intermediaries are able to broaden access to foreign job and high wage opportunities. Commercialization effectively raises the transaction costs for contract migration. Studies on recruitment costs and fees show that self-solicited foreign employment costs less than employment obtained through recruitment agents and intermediaries. The difference in the 2 prices is due, not only to overhead costs of intermediation, but more importantly to the rent exacted by agents from having job information and placement rights. In the Philippines in October 1987 the average placement fee was P8000, greatly exceeding the mandated maximum fee level of P5000. This average is understated because the computation includes the 17% who do not pay any fees. The widespread and popular view of recruitment intermediaries is negative, dominated by images of abuses and victims. Private intermediaries and the government bureaucracy need each other. Intermediaries need government; their consistent demand for incentives and protection is indicative. On the other hand, government expands its supervision of control of overseas employment via the

  14. Advanced Concepts: Aneutronic Fusion Power and Propulsion

    NASA Technical Reports Server (NTRS)

    Chapman, John J.

    2012-01-01

    Aneutronic Fusion for In-Space thrust, power. Clean energy & potential nuclear gains. Fusion plant concepts, potential to use advanced fuels. Methods to harness ionic momentum for high Isp thrust plus direct power conversion into electricity will be presented.

  15. Cold fusion catalyzed by muons and electrons

    SciTech Connect

    Kulsrud, R.M.

    1990-10-01

    Two alternative methods have been suggested to produce fusion power at low temperature. The first, muon catalyzed fusion or MCF, uses muons to spontaneously catalyze fusion through the muon mesomolecule formation. Unfortunately, this method fails to generate enough fusion energy to supply the muons, by a factor of about ten. The physics of MCF is discussed, and a possible approach to increasing the number of MCF fusions generated by each muon is mentioned. The second method, which has become known as Cold Fusion,'' involves catalysis by electrons in electrolytic cells. The physics of this process, if it exists, is more mysterious than MCF. However, it now appears to be an artifact, the claims for its reality resting largely on experimental errors occurring in rather delicate experiments. However, a very low level of such fusion claimed by Jones may be real. Experiments in cold fusion will also be discussed.

  16. Commercial Data Mining Software

    NASA Astrophysics Data System (ADS)

    Zhang, Qingyu; Segall, Richard S.

    This chapter discusses selected commercial software for data mining, supercomputing data mining, text mining, and web mining. The selected software are compared with their features and also applied to available data sets. The software for data mining are SAS Enterprise Miner, Megaputer PolyAnalyst 5.0, PASW (formerly SPSS Clementine), IBM Intelligent Miner, and BioDiscovery GeneSight. The software for supercomputing are Avizo by Visualization Science Group and JMP Genomics from SAS Institute. The software for text mining are SAS Text Miner and Megaputer PolyAnalyst 5.0. The software for web mining are Megaputer PolyAnalyst and SPSS Clementine . Background on related literature and software are presented. Screen shots of each of the selected software are presented, as are conclusions and future directions.

  17. Exo-endo cellulase fusion protein

    DOEpatents

    Bower, Benjamin S.; Larenas, Edmund A.; Mitchinson, Colin

    2012-01-17

    The present invention relates to a heterologous exo-endo cellulase fusion construct, which encodes a fusion protein having cellulolytic activity comprising a catalytic domain derived from a fungal exo-cellobiohydrolase and a catalytic domain derived from an endoglucanase. The invention also relates to vectors and fungal host cells comprising the heterologous exo-endo cellulase fusion construct as well as methods for producing a cellulase fusion protein and enzymatic cellulase compositions.

  18. Inertial confinement fusion (ICF) review

    SciTech Connect

    Hammer, D.; Dyson, F.; Fortson, N.; Novick, B.; Panofsky, W.; Rosenbluth, M.; Treiman, S.; York, H.

    1996-03-01

    During its 1996 winter study JASON reviewed the DOE Inertial Confinement Fusion (ICF) program. This included the National Ignition Facility (NIF) and proposed studies. The result of the review was to comment on the role of the ICF program in support of the DOE Science Based Stockpile Stewardship program.

  19. Seismic data fusion anomaly detection

    NASA Astrophysics Data System (ADS)

    Harrity, Kyle; Blasch, Erik; Alford, Mark; Ezekiel, Soundararajan; Ferris, David

    2014-06-01

    Detecting anomalies in non-stationary signals has valuable applications in many fields including medicine and meteorology. These include uses such as identifying possible heart conditions from an Electrocardiography (ECG) signals or predicting earthquakes via seismographic data. Over the many choices of anomaly detection algorithms, it is important to compare possible methods. In this paper, we examine and compare two approaches to anomaly detection and see how data fusion methods may improve performance. The first approach involves using an artificial neural network (ANN) to detect anomalies in a wavelet de-noised signal. The other method uses a perspective neural network (PNN) to analyze an arbitrary number of "perspectives" or transformations of the observed signal for anomalies. Possible perspectives may include wavelet de-noising, Fourier transform, peak-filtering, etc.. In order to evaluate these techniques via signal fusion metrics, we must apply signal preprocessing techniques such as de-noising methods to the original signal and then use a neural network to find anomalies in the generated signal. From this secondary result it is possible to use data fusion techniques that can be evaluated via existing data fusion metrics for single and multiple perspectives. The result will show which anomaly detection method, according to the metrics, is better suited overall for anomaly detection applications. The method used in this study could be applied to compare other signal processing algorithms.

  20. Magnetic fusion: progress -> stagnation -> degradation

    NASA Astrophysics Data System (ADS)

    Zakharov, Leonid

    2012-10-01

    ``The theory of the failure of magnetic fusion,'' created in 2004 and presented to APS-2007 introduced the notion of the ``difficult'' and ``complicated'' stages of the program and described them details. At the first phase the emerging fusion science was created under strong leadership. Progress was visible on year to year basis, and the program was easy to manage. The complicated phase started in the late 1980s, when the plasma physics appeared to be incapable to implement the mission of ITER to test nuclear components of a fusion reactor. Then, the failure of TFTR (PPPL, USA) and JET (Culham, UK) in the mid 1990 to demonstrate QDT=1 and the blindness of their leaders to already visible means to resolve the problem, were a clear indication of an irreversible stagnation. In fact, right after 2007, it became clear that in the case of a large system of human ``particles'' (scientists) two phases have a continuation. The internal degrees of freedom, otherwise protected from external perturbations by a strong dedication to the scientific method, are now eroding and collapsing. The loss of science in addressing confinement, stability, power extraction, fueling, stationary regimes issues makes the current program irrelevant to fusion energy. A fresh approach should be taken.

  1. Magnetic fusion and project ITER

    SciTech Connect

    Park, H.K.

    1992-01-01

    It has already been demonstrated that our economics and international relationship are impacted by an energy crisis. For the continuing prosperity of the human race, a new and viable energy source must be developed within the next century. It is evident that the cost will be high and will require a long term commitment to achieve this goal due to a high degree of technological and scientific knowledge. Energy from the controlled nuclear fusion is a safe, competitive, and environmentally attractive but has not yet been completely conquered. Magnetic fusion is one of the most difficult technological challenges. In modem magnetic fusion devices, temperatures that are significantly higher than the temperatures of the sun have been achieved routinely and the successful generation of tens of million watts as a result of scientific break-even is expected from the deuterium and tritium experiment within the next few years. For the practical future fusion reactor, we need to develop reactor relevant materials and technologies. The international project called International Thermonuclear Experimental Reactor (ITER)'' will fulfill this need and the success of this project will provide the most attractive long-term energy source for mankind.

  2. Magnetic fusion and project ITER

    SciTech Connect

    Park, H.K.

    1992-09-01

    It has already been demonstrated that our economics and international relationship are impacted by an energy crisis. For the continuing prosperity of the human race, a new and viable energy source must be developed within the next century. It is evident that the cost will be high and will require a long term commitment to achieve this goal due to a high degree of technological and scientific knowledge. Energy from the controlled nuclear fusion is a safe, competitive, and environmentally attractive but has not yet been completely conquered. Magnetic fusion is one of the most difficult technological challenges. In modem magnetic fusion devices, temperatures that are significantly higher than the temperatures of the sun have been achieved routinely and the successful generation of tens of million watts as a result of scientific break-even is expected from the deuterium and tritium experiment within the next few years. For the practical future fusion reactor, we need to develop reactor relevant materials and technologies. The international project called ``International Thermonuclear Experimental Reactor (ITER)`` will fulfill this need and the success of this project will provide the most attractive long-term energy source for mankind.

  3. Fusion blanket inherent safety assessment

    SciTech Connect

    Sze, D.K.; Jung, J.; Cheng, E.T.

    1986-01-01

    The inherent safety aspect of TPSS reactor blankets has been investigated. The idea is to design the blanket so safe that cost savings can be realized such as through non-nuclear grading construction. If the blanket materials are carefully selected, inherent safety is feasible for fusion reactor blankets up to 5 to 10 MW/m/sup 2/ neutron wall loading.

  4. Membrane fusion during phage lysis

    PubMed Central

    Berry, Joel; Kongari, Rohit; Cahill, Jesse; Young, Ry

    2015-01-01

    In general, phages cause lysis of the bacterial host to effect release of the progeny virions. Until recently, it was thought that degradation of the peptidoglycan (PG) was necessary and sufficient for osmotic bursting of the cell. Recently, we have shown that in Gram-negative hosts, phage lysis also requires the disruption of the outer membrane (OM). This is accomplished by spanins, which are phage-encoded proteins that connect the cytoplasmic membrane (inner membrane, IM) and the OM. The mechanism by which the spanins destroy the OM is unknown. Here we show that the spanins of the paradigm coliphage lambda mediate efficient membrane fusion. This supports the notion that the last step of lysis is the fusion of the IM and OM. Moreover, data are provided indicating that spanin-mediated fusion is regulated by the meshwork of the PG, thus coupling fusion to murein degradation by the phage endolysin. Because endolysin function requires the formation of μm-scale holes by the phage holin, the lysis pathway is seen to require dramatic dynamics on the part of the OM and IM, as well as destruction of the PG. PMID:25870259

  5. Driver drowsiness detection using multimodal sensor fusion

    NASA Astrophysics Data System (ADS)

    Andreeva, Elena O.; Aarabi, Parham; Philiastides, Marios G.; Mohajer, Keyvan; Emami, Majid

    2004-04-01

    This paper proposes a multi-modal sensor fusion algorithm for the estimation of driver drowsiness. Driver sleepiness is believed to be responsible for more than 30% of passenger car accidents and for 4% of all accident fatalities. In commercial vehicles, drowsiness is blamed for 58% of single truck accidents and 31% of commercial truck driver fatalities. This work proposes an innovative automatic sleep-onset detection system. Using multiple sensors, the driver"s body is studied as a mechanical structure of springs and dampeners. The sleep-detection system consists of highly sensitive triple-axial accelerometers to monitor the driver"s upper body in 3-D. The subject is modeled as a linear time-variant (LTV) system. An LMS adaptive filter estimation algorithm generates the transfer function (i.e. weight coefficients) for this LTV system. Separate coefficients are generated for the awake and asleep states of the subject. These coefficients are then used to train a neural network. Once trained, the neural network classifies the condition of the driver as either awake or asleep. The system has been tested on a total of 8 subjects. The tests were conducted on sleep-deprived individuals for the sleep state and on fully awake individuals for the awake state. When trained and tested on the same subject, the system detected sleep and awake states of the driver with a success rate of 95%. When the system was trained on three subjects and then retested on a fourth "unseen" subject, the classification rate dropped to 90%. Furthermore, it was attempted to correlate driver posture and sleepiness by observing how car vibrations propagate through a person"s body. Eight additional subjects were studied for this purpose. The results obtained in this experiment proved inconclusive which was attributed to significant differences in the individual habitual postures.

  6. Fusion probability in heavy nuclei

    NASA Astrophysics Data System (ADS)

    Banerjee, Tathagata; Nath, S.; Pal, Santanu

    2015-03-01

    Background: Fusion between two massive nuclei is a very complex process and is characterized by three stages: (a) capture inside the potential barrier, (b) formation of an equilibrated compound nucleus (CN), and (c) statistical decay of the CN leading to a cold evaporation residue (ER) or fission. The second stage is the least understood of the three and is the most crucial in predicting yield of superheavy elements (SHE) formed in complete fusion reactions. Purpose: A systematic study of average fusion probability, , is undertaken to obtain a better understanding of its dependence on various reaction parameters. The study may also help to clearly demarcate onset of non-CN fission (NCNF), which causes fusion probability, PCN, to deviate from unity. Method: ER excitation functions for 52 reactions leading to CN in the mass region 170-220, which are available in the literature, have been compared with statistical model (SM) calculations. Capture cross sections have been obtained from a coupled-channels code. In the SM, shell corrections in both the level density and the fission barrier have been included. for these reactions has been extracted by comparing experimental and theoretical ER excitation functions in the energy range ˜5 %-35% above the potential barrier, where known effects of nuclear structure are insignificant. Results: has been shown to vary with entrance channel mass asymmetry, η (or charge product, ZpZt ), as well as with fissility of the CN, χCN. No parameter has been found to be adequate as a single scaling variable to determine . Approximate boundaries have been obtained from where starts deviating from unity. Conclusions: This study quite clearly reveals the limits of applicability of the SM in interpreting experimental observables from fusion reactions involving two massive nuclei. Deviation of from unity marks the beginning of the domain of dynamical models of fusion. Availability of precise ER cross

  7. Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas.

    PubMed

    Winnes, Marta; Mölne, Lena; Suurküla, Mart; Andrén, Ywonne; Persson, Fredrik; Enlund, Fredrik; Stenman, Göran

    2007-06-01

    Fusion of the CREB regulated transcription coactivator CRTC1 (a.k.a. MECT1, TORC1, or WAMTP1) to the Notch coactivator MAML2 is a characteristic feature of low-grade mucoepidermoid carcinomas of salivary and bronchial glands. The CRTC1-MAML2 fusion protein acts by inducing transcription of cAMP/CREB target genes, and this activity is crucial for the transforming properties of the protein. Here we show that the CRTC1-MAML2 gene fusion is also frequent in benign hidradenomas of the skin. FISH and RT-PCR analyses revealed that hidradenomas are genetically heterogeneous, and that 10 of the 20 tumors analyzed (50%) contained the CRTC1-MAML2 gene fusion and expressed the resulting fusion transcript. Immunohistochemical analysis demonstrated expression of the fusion protein in the majority of tumor cells, including clear cells, poroid cells, and cells with epidermoid and ductal differentiation. In addition, we could show that all fusion-positive tumors were morphologically distinguished by the presence of more or less abundant areas of clear cells whereas all fusion-negative tumors lacked clear cells. Our findings thus demonstrate that the CRTC1-MAML2 gene fusion is frequent in hidradenomas and is associated with clear cell variants of this tumor. Taken together, the present and previous observations indicate that the CRTC1-MAML2 fusion is etiologically linked to benign and low-grade malignant tumors originating from diverse exocrine glands rather than being linked to a separate tumor entity.

  8. Flywheel induction motor-generator for magnet power supply in small fusion device

    NASA Astrophysics Data System (ADS)

    Hatakeyma, S.; Yoshino, F.; Tsutsui, H.; Tsuji-Iio, S.

    2016-04-01

    A flywheel motor-generator (MG) for the toroidal field (TF) coils of a small fusion device was developed which utilizes a commercially available squirrel-cage induction motor. Advantages of the MG are comparably-long duration, quick power response, and easy implementation of power control compared with conventional capacitor-type power supply. A 55-kW MG was fabricated, and TF coils of a small fusion device were energized. The duration of the current flat-top was extended to 1 s which is much longer than those of conventional small devices (around 10-100 ms).

  9. Flywheel induction motor-generator for magnet power supply in small fusion device.

    PubMed

    Hatakeyma, S; Yoshino, F; Tsutsui, H; Tsuji-Iio, S

    2016-04-01

    A flywheel motor-generator (MG) for the toroidal field (TF) coils of a small fusion device was developed which utilizes a commercially available squirrel-cage induction motor. Advantages of the MG are comparably-long duration, quick power response, and easy implementation of power control compared with conventional capacitor-type power supply. A 55-kW MG was fabricated, and TF coils of a small fusion device were energized. The duration of the current flat-top was extended to 1 s which is much longer than those of conventional small devices (around 10-100 ms). PMID:27131676

  10. Flywheel induction motor-generator for magnet power supply in small fusion device.

    PubMed

    Hatakeyma, S; Yoshino, F; Tsutsui, H; Tsuji-Iio, S

    2016-04-01

    A flywheel motor-generator (MG) for the toroidal field (TF) coils of a small fusion device was developed which utilizes a commercially available squirrel-cage induction motor. Advantages of the MG are comparably-long duration, quick power response, and easy implementation of power control compared with conventional capacitor-type power supply. A 55-kW MG was fabricated, and TF coils of a small fusion device were energized. The duration of the current flat-top was extended to 1 s which is much longer than those of conventional small devices (around 10-100 ms).

  11. Inertial fusion science and technology for the next century

    SciTech Connect

    Campbell, E M; Hogan, W J; Landes, S

    1999-09-10

    This paper reviews the leading edge of the basic and applied science and technology that use high-intensity facilities and looks at what opportunities lie ahead. The more than 15,000 experiments on the Nova laser since 1985 and many thousands more on other laser, particle beam, and pulsed power facilities around the world have established the new laboratory field of high-energy-density plasma physics and have furthered development of inertial fusion. New capabilities such as those provided by high-brightness femtosecond lasers have enabled the study of matter in conditions previously unachievable on earth. These experiments, along with advanced calculations now practical because of the progress in computing capability, have established the specifications for the National Ignition Facility and Laser MegaJoule and have enhanced new scientific fields such as laboratory astrophysics. Science and technology developed in inertial fusion have found near-term commercial use, have enabled steady progress toward the goal of fusion ignition and gain in the laboratory, and have opened up new fields of study for the 21st century.

  12. A laser device for fusion of nasal mucosa

    NASA Astrophysics Data System (ADS)

    Sooklal, Valmiki; McClure, Jesse; Hooper, Luke; Larson, Michael

    2010-02-01

    A prototype device has been created to fuse septal tissue membranes as an alternative to sutures or staples through the controlled application of laser heating and pressure to induce protein denaturation and subsequent tissue fusion, through renaturation and intertwining, across the interface. Lasers have been used to close wounds in controlled laboratory tests over the last 15 years. Many encouraging results have been obtained; however, no commercial delivery systems are currently available. This is due primarily to two factors: requiring an inordinate amount of experience on the part of the operator, and attempting to achieve general applicability for multiple tissue systems. The present device overcomes these barriers as it is tailored for the particular application of septal laser fusion, namely for the coaptation of mucoperichondrial membranes. The important parameters involved in fusing biological tissues are identified. The development of the device followed from computational modeling based on Monte Carlo simulation of photon transport and on engineering firstprinciples. Experiments were designed and analyzed using orthogonal arrays, employing a subset of the relevant parameters, i.e., laser irradiance, dwell time and spot size, for a range of wavelengths. The in vitro fusion experiments employed 1cm by 1cm sections of equine nasal mucosa having a nominal thickness of 1mm.

  13. Application of Fusion Gyrotrons to Enhanced Geothermal Systems (EGS)

    NASA Astrophysics Data System (ADS)

    Woskov, P.; Einstein, H.; Oglesby, K.

    2013-10-01

    The potential size of geothermal energy resources is second only to fusion energy. Advances are needed in drilling technology and heat reservoir formation to realize this potential. Millimeter-wave (MMW) gyrotrons and related technologies developed for fusion energy research could contribute to enabling EGS. Directed MMW energy can be used to advance rock penetration capabilities, borehole casing, and fracking. MMWs are ideally suited because they can penetrate through small particulate extraction plumes, can be efficiently guided long distances in borehole dimensions, and continuous megawatt sources are commercially available. Laboratory experiments with a 10 kW, 28 GHz CPI gyrotron have shown that granite rock can be fractured and melted with power intensities of about 1 kW/cm2 and minute exposure times. Observed melted rock MMW emissivity and estimated thermodynamics suggest that penetrating hot, hard crystalline rock formations may be economic with fusion research developed MMW sources. Supported by USDOE, Office of Energy Efficiency and Renewable Energy and Impact Technologies, LLC.

  14. An introduction to multisensor data fusion

    SciTech Connect

    Hall, D.L.; Llinas, J.

    1997-01-01

    Multisensor data fusion is an emerging technology applied to Department of Defense (DoD) areas such as automated target recognition, battlefield surveillance, and guidance and control of autonomous vehicles, and to non-DoD applications such as monitoring of complex machinery, medical diagnosis, and smart buildings. Techniques for multisensor data fusion are drawn from a wide range of areas including artificial intelligence, pattern recognition, statistical estimation, and other areas. This paper provides a tutorial on data fusion, introducing data fusion applications, process models, and identification of applicable techniques. Comments are made on the state-of-the-art in data fusion.

  15. Data fusion analysis of a surface direct-current resistivity and well pick data set

    SciTech Connect

    Clayton, E.A.; Lewis, R.E.

    1995-09-01

    Pacific Northwest Laboratory (PNL) has been tasked with testing, debugging, and refining the Hanford Site data fusion workstation (DFW), with the assistance of Coleman Research Corporation (CRC), before delivering the DFW to the environmental restoration client at the Hanford Site. Data fusion is the mathematical combination (or fusion) of disparate data sets into a single interpretation. The data fusion software used in this study was developed by CRC. This report discusses the results of evaluating a surface direct-current (dc) resistivity and well-pick data set using two methods: data fusion technology and commercially available software (i.e., RESIX Plus from Interpex Ltd., Golden, Colorado), the conventional method of analysis. The report compares the two technologies; describes the survey, procedures, and results; and includes conclusions and recommendations. The surface dc resistivity and well-pick data set had been acquired by PNL from a study performed in May 1993 at Eielson Air Force Base near Fairbanks, Alaska. The resistivity survey data were acquired to map the top of permafrost in support of a hydrogeologic study. This data set provided an excellent opportunity to test and refine the dc resistivity capabilities of the DFW; previously, the data fusion software was untested on dc resistivity data. The DFW was used to evaluate the dc resistivity survey data and to produce a 3-dimensional earth model of the study area.

  16. Physics Issues of Heavy-Ion-Beam-Driven Inertial Confinement Fusion*

    NASA Astrophysics Data System (ADS)

    Celata, Christine

    2003-04-01

    The heavy ion fusion concept envisions using of the order of a hundred intense few-GeV ion beams to implode an inertial fusion target, in order to produce commercial electricity using nuclear fusion reactions. The current density of the beams is high enough that each beam is a nonneutral plasma, with dynamics dominated by space charge. The stability, wave phenomena, and nonlinear dynamics of such a system then determine whether beam quality can be preserved through the length of the accelerator and final focus, so that an adequate focus on target occurs. Five experiments are currently exploring the physics of the transport, neutralization, and focusing of these intense heavy ion beams. The targets for heavy ion fusion build upon the work done for indirect drive, laser targets for the National Ignition Facility (NIF). Many of the fundamental target physics issues for heavy ion targets will be addressed on NIF. Using these targets for a power plant adds additional issues, including heavy ion beam/target interactions, the interface with the fusion chamber, and mass-production of targets. In this paper the physics issues for heavy ion fusion will be discussed, and results from both the experimental program and an extensive simulation program will be shown.

  17. Commercial aircraft wake vortices

    NASA Astrophysics Data System (ADS)

    Gerz, Thomas; Holzäpfel, Frank; Darracq, Denis

    2002-04-01

    This paper discusses the problem of wake vortices shed by commercial aircraft. It presents a consolidated European view on the current status of knowledge of the nature and characteristics of aircraft wakes and of technical and operational procedures of minimizing and predicting the vortex strength and avoiding wake encounters. Methodological aspects of data evaluation and interpretation, like the description of wake ages, the characterization of wake vortices, and the proper evaluation of wake data from measurement and simulation, are addressed in the first part. In the second part an inventory of our knowledge is given on vortex characterization and control, prediction and monitoring of vortex decay, vortex detection and warning, vortex encounter models, and wake-vortex safety assessment. Each section is concluded by a list of questions and required actions which may help to guide further research activities. The primary objective of the joint international efforts in wake-vortex research is to avoid potentially hazardous wake encounters for aircraft. Shortened aircraft separations under appropriate meteorological conditions, whilst keeping or even increasing the safety level, is the ultimate goal. Reduced time delays on the tactical side and increased airport capacities on the strategic side will be the benefits of these ambitious ventures for the air transportation industry and services.

  18. Fusion energy calorimeter for the tokamak fusion test reactor

    SciTech Connect

    Jassby, D.L.; Imel, G.R.

    1981-04-01

    One and two-dimensional neutronic analyses treating the transport and scattering of neutrons and the production and transport of gamma rays in the TFTR demonstrate that the fusion energy production in a D-T pulse in the TFTR can be determined with an uncertainty of +- 15% or less, simply by integrating the measured profile of temperature increase along the central radial axis of a large hydrocarbon moderator that fills the bay between adjacent toroidal-field coils, just outside the vacuum vessel. Limitations in thermopile temperature measurements dictate a minimum fusion-neutron fluence at the vacuum vessel of the order of 10/sup 12/ n/cm/sup 2/ per pulse (a source strength of 10/sup 18/ n/pulse in TFTR), in order that this simple calorimeter can provide useful accuracy.

  19. Analytical parametrization of fusion barriers using proximity potentials

    NASA Astrophysics Data System (ADS)

    Dutt, Ishwar; Puri, Rajeev K.

    2010-06-01

    Using the three versions of proximity potentials, namely proximity 1977, proximity 1988, and proximity 2000, we present a pocket formula for fusion barrier heights and positions. This was achieved by analyzing as many as 400 reactions with mass between 15 and 296. Our parametrized formula can reproduced the exact barrier heights and positions within an accuracy of ±1%. A comparison with the experimental data is also in good agreement.

  20. West European magnetic confinement fusion research

    SciTech Connect

    McKenney, B.L.; McGrain, M. . Foreign Applied Sciences Assessment Center); Hazeltine, R.D. . Inst. for Fusion Studies); Gentle, K.W. ); Hogan, J.T. ); Porkolab, M. . Dept. of Physics); Sigmar

    1990-01-01

    This report presents a technical assessment and review of the West European program in magnetic confinement fusion by a panel of US scientists and engineers active in fusion research. Findings are based on the scientific and technical literature, on laboratory reports and preprints, and on the personal experiences and collaborations of the panel members. Concerned primarily with developments during the past 10 years, from 1979 to 1989, the report assesses West European fusion research in seven technical areas: tokamak experiments; magnetic confinement technology and engineering; fusion nuclear technology; alternate concepts; theory; fusion computations; and program organization. The main conclusion emerging from the analysis is that West European fusion research has attained a position of leadership in the international fusion program. This distinction reflects in large measure the remarkable achievements of the Joint European Torus (JET). However, West European fusion prominence extends beyond tokamak experimental physics: the program has demonstrated a breadth of skill in fusion science and technology that is not excelled in the international effort. It is expected that the West European primacy in central areas of confinement physics will be maintained or even increased during the early 1990s. The program's maturity and commitment kindle expectations of dramatic West European advances toward the fusion energy goal. For example, achievement of fusion breakeven is expected first in JET, before 1995.

  1. Fusion of Enveloped Viruses in Endosomes.

    PubMed

    White, Judith M; Whittaker, Gary R

    2016-06-01

    Ari Helenius launched the field of enveloped virus fusion in endosomes with a seminal paper in the Journal of Cell Biology in 1980. In the intervening years, a great deal has been learned about the structures and mechanisms of viral membrane fusion proteins as well as about the endosomes in which different enveloped viruses fuse and the endosomal cues that trigger fusion. We now recognize three classes of viral membrane fusion proteins based on structural criteria and four mechanisms of fusion triggering. After reviewing general features of viral membrane fusion proteins and viral fusion in endosomes, we delve into three characterized mechanisms for viral fusion triggering in endosomes: by low pH, by receptor binding plus low pH and by receptor binding plus the action of a protease. We end with a discussion of viruses that may employ novel endosomal fusion-triggering mechanisms. A key take-home message is that enveloped viruses that enter cells by fusing in endosomes traverse the endocytic pathway until they reach an endosome that has all of the environmental conditions (pH, proteases, ions, intracellular receptors and lipid composition) to (if needed) prime and (in all cases) trigger the fusion protein and to support membrane fusion.

  2. Molecular mechanism of mitochondrial membrane fusion.

    PubMed

    Griffin, Erik E; Detmer, Scott A; Chan, David C

    2006-01-01

    Mitochondrial fusion requires coordinated fusion of the outer and inner membranes. This process leads to exchange of contents, controls the shape of mitochondria, and is important for mitochondrial function. Two types of mitochondrial GTPases are essential for mitochondrial fusion. On the outer membrane, the fuzzy onions/mitofusin proteins form complexes in trans that mediate homotypic physical interactions between adjacent mitochondria and are likely directly involved in outer membrane fusion. Associated with the inner membrane, the OPA1 dynamin-family GTPase maintains membrane structure and is a good candidate for mediating inner membrane fusion. In yeast, Ugo1p binds to both of these GTPases to form a fusion complex, although a related protein has yet to be found in mammals. An understanding of the molecular mechanism of fusion may have implications for Charcot-Marie-Tooth subtype 2A and autosomal dominant optic atrophy, neurodegenerative diseases caused by mutations in Mfn2 and OPA1.

  3. Security on the US Fusion Grid

    SciTech Connect

    Burruss, Justin R.; Fredian, Tom W.; Thompson, Mary R.

    2005-06-01

    The National Fusion Collaboratory project is developing and deploying new distributed computing and remote collaboration technologies with the goal of advancing magnetic fusion energy research. This work has led to the development of the US Fusion Grid (FusionGrid), a computational grid composed of collaborative, compute, and data resources from the three large US fusion research facilities and with users both in the US and in Europe. Critical to the development of FusionGrid was the creation and deployment of technologies to ensure security in a heterogeneous environment. These solutions to the problems of authentication, authorization, data transfer, and secure data storage, as well as the lessons learned during the development of these solutions, may be applied outside of FusionGrid and scale to future computing infrastructures such as those for next-generation devices like ITER.

  4. Data security on the national fusion grid

    SciTech Connect

    Burruss, Justine R.; Fredian, Tom W.; Thompson, Mary R.

    2005-06-01

    The National Fusion Collaboratory project is developing and deploying new distributed computing and remote collaboration technologies with the goal of advancing magnetic fusion energy research. This work has led to the development of the US Fusion Grid (FusionGrid), a computational grid composed of collaborative, compute, and data resources from the three large US fusion research facilities and with users both in the US and in Europe. Critical to the development of FusionGrid was the creation and deployment of technologies to ensure security in a heterogeneous environment. These solutions to the problems of authentication, authorization, data transfer, and secure data storage, as well as the lessons learned during the development of these solutions, may be applied outside of FusionGrid and scale to future computing infrastructures such as those for next-generation devices like ITER.

  5. 2002 Fusion Summer Study Executive Summary

    NASA Astrophysics Data System (ADS)

    Bangerter, Roger; Navratil, Gerald; Sauthoff, Ned

    2001-09-01

    The 2002 Fusion Summer Study was conducted July 8-19, 2002, in Snowmass, CO, and carried out a critical assessment of major next steps in the fusion energy sciences program in both magnetic fusion energy (MFE) and inertial fusion energy (IFE). The conclusions of this study were based on analysis led by over 60 conveners working with hundreds of members of the fusion energy sciences community extending over eight months. This effort culminated in two weeks of intense discussion by over 250 U.S. and 30 foreign fusion physicists and engineers present at the 2002 Fusion Summer Study. This is the Executive Summary of the study report. Details are posted at http://web.gat.com/snowmass

  6. Measurement of the fusion probability, PCN, for hot fusion reactions

    NASA Astrophysics Data System (ADS)

    Yanez, R.; Loveland, W.; Barrett, J. S.; Yao, L.; Back, B. B.; Zhu, S.; Khoo, T. L.

    2013-07-01

    Background: The cross section for forming a heavy evaporation residue in fusion reactions depends on the capture cross section, the fusion probability, PCN, i.e., the probability that the projectile-target system will evolve inside the fission saddle point to form a completely fused system rather than reseparating (quasifission), and the survival of the completely fused system against fission. PCN is the least known of these quantities.Purpose: We want to determine PCN for the reactions of 101.2 MeV 18O, 147.3 MeV 26Mg, 170.9 MeV 30Si, and 195.3 MeV 36S with 197Au.Methods: We measured the fission fragment angular distributions for these reactions and used the formalism of Back to deduce the fusion-fission and quasifission cross sections. From these quantities we deduced PCN for each reaction.Results: The values of PCN for the reactions of 101.2 MeV 18O, 147.3 MeV 26Mg, 170.9 MeV 30Si, and 195.3 MeV 36S with 197Au are 0.66, 1.00, 0.06, and 0.13, respectively.Conclusions: The new measured values of PCN agree roughly with the semiempirical systematic dependence of PCN upon fissility for excited nuclei.

  7. Fission Fusion Hybrids: a nearer term application of Fusion

    NASA Astrophysics Data System (ADS)

    Kotschenreuther, M.; Valanju, P.; Mahajan, S.; Covele, B.

    2011-10-01

    Fission-fusion hybrids enjoy unique advantages for addressing long standing societal acceptability issues of nuclear fission power at a much lower level of technical development than a competitive fusion power plant. For waste incineration, hybrids burn intransigent transuranic residues (with the long lived biohazard) from light water reactors (LWRs). The number of hybrids needed is 5-10 times less than the corresponding number of fast reactors (FRs). The highly sub-critical hybrids, with a thermal/epithermal spectrum, incinerate > 95% of the waste in decades rather than the centuries needed for FRs. For fuel production, hybrids can produce fuel for 3-4 times as many LWRs with no fuel reprocessing. Thorium fuel rods exposed to neutrons in the hybrid reach fissile concentrations that enable efficient burning in LWR without the proliferation risks of reprocessing. The proliferation risks of this method are far less than other fuel breeding approaches, including today's gas centrifuge. With this cycle, US Thorium reserves could supply the entire US electricity supply for centuries. The centerpiece of the fuel cycle is a high power density Compact Fusion Neutron Source (major+minor radius ~ 2.5-3.5 m), which is made feasible by the super-X divertor.

  8. The elementary fusion modalities of osteoclasts.

    PubMed

    Søe, Kent; Hobolt-Pedersen, Anne-Sofie; Delaisse, Jean-Marie

    2015-04-01

    The last step of the osteoclast differentiation process is cell fusion. Most efforts to understand the fusion mechanism have focused on the identification of molecules involved in the fusion process. Surprisingly, the basic fusion modalities, which are well known for fusion of other cell types, are not known for the osteoclast. Here we show that osteoclast fusion partners are characterized by differences in mobility, nuclearity, and differentiation level. Our demonstration was based on time-laps videos of human osteoclast preparations from three donors where 656 fusion events were analyzed. Fusions between a mobile and an immobile partner were most frequent (62%), while fusion between two mobile (26%) or two immobile partners (12%) was less frequent (p<0.001). In general, the immobile fusion partner contained more nuclei than the mobile one (p<0.01). Furthermore, enrichment in nuclei of an osteoclast with three or more nuclei resulted from fusion with a mono-nucleated cell in 67% of the cases (p<0.001), while mono-nucleated cells fused with a multinucleated cell in 61% of the cases (p<0.05). This observation suggested that a more mature osteoclast prefers to fuse with a less mature pre-osteoclast. This hypothesis was supported by a nucleus-tracing approach in a co-culture of more and less differentiated pre-osteoclasts/osteoclasts. Furthermore, we found that osteoclast fusion proceeds through primarily two different types of cell contacts: phagocytic-cup and broad-contact-surfaces (>80% of all fusions). We conclude that osteoclasts most often gain nuclei by addition of one nucleus at a time, and that this nucleus is most often delivered by a moving cell to an immobile cell. These characteristics fit the in vivo observations where mono-nucleated precursors migrating from the bone marrow fuse with more mature osteoclasts sitting on the bone surface. They also fit the fusion modalities of other cell types.

  9. Commercial Art I and Commercial Art II: An Instructional Guide.

    ERIC Educational Resources Information Center

    Montgomery County Public Schools, Rockville, MD.

    A teacher's guide for two sequential one-year commercial art courses for high school students is presented. Commercial Art I contains three units: visual communication, product design, and environmental design. Students study visual communication by analyzing advertising techniques, practicing fundamental drawing and layout techniques, creating…

  10. Fundamentals of Commercial Art. Module 1. Commercial Art. Instructor's Guide.

    ERIC Educational Resources Information Center

    Davis, Diane; Tadrick, Christine

    This module is the first of five in the Commercial Art series. The curriculum guide is designed for competency-based teaching and testing. Within this module on fundamentals of commercial art are six instructional units. A cross-reference table reveals how the instructional components of the module relate to Missouri competencies. Each unit…

  11. Fusion burn dynamics in dense Z-pinch (DZP)

    SciTech Connect

    Krakowski, R.A.

    1990-04-01

    The fusion burn dynamics and energy yield of the dense Z-pinch (DZP) are examined using a profile-averaged, zero-dimensional, time dependent model. A range of conditions (fuel, line density, voltage, fusion-product heating, enthalpy endloss, density and temperature profiles, current rise rate, electrode impurities) are examined. Magneto-hydrodynamic stability is assumed, and initial conditions are based on those ideally existing after the melting and ionization of a solid fiber of fusion fuel. Plasma conditions required of neutron sources for materials testing ({dot S}{sub n} {ge} 10{sup 19} n/s) and for possible commercial power production (ratio of fusion energy yield to energy input, Q{sub p} {approx equal} 15, lower values if reversible recovery of a fraction of the magnetic energy is possible) are described. If f{sub B} {approx gt} 0.8 fractional fuel burnup is possible in a nominal 800-ns DT discharge (200-ns current-rise phase at 20 MV/m followed by a 500-ns constant-current crowbarred phase), reactor-relevant values of Q{sub p} may be possible. For the simpler (and shorter) constant-voltage discharge (e.g., no voltage crowbar) the value of Q{sub p} is in the range 5--10 for discharges below 200-ns duration. Smaller levels of fuel burnup, shorter discharges, or generally lower levels of Q{sub p} will require a reversible energy transfer system to meet reactor energy-balance requirements. Imposition of a plasma current rise-time constraint that may be needed for stable plasma operation (e.g., I > 10{sup 12} A/s) will burnup, Q{sub p} and discharge time to an extent where reversible energy/transfer system will be required to meet reactor energy- balance requirements. 25 refs.

  12. U1A Complex

    ScienceCinema

    None

    2016-07-12

    Some of the most sophisticated experiments in the stockpile stewardship program are conducted in an environmentally safe manner, nearly 1000 feet below the ground at the site. The U1a complex a sprawling underground laboratory and tunnel complex is home to a number of unique capabilities.

  13. U1A Complex

    SciTech Connect

    2014-10-28

    Some of the most sophisticated experiments in the stockpile stewardship program are conducted in an environmentally safe manner, nearly 1000 feet below the ground at the site. The U1a complex a sprawling underground laboratory and tunnel complex is home to a number of unique capabilities.

  14. Interpreting inertial fusion neutron spectra

    NASA Astrophysics Data System (ADS)

    Munro, David H.

    2016-03-01

    A burning laser fusion plasma produces a neutron spectrum first described by Brysk (1973 Plasma Phys. Control. Fusion 15 611). This and more recent work deals with the spectrum produced by a single fluid element. The distribution of temperatures and velocities in multiple fluid elements combine in any real spectrum; we derive formulas for how the neutron spectrum averages these contributions. The single element momentum spectrum is accurately Gaussian, but the multi-element spectrum exhibits higher moments. In particular, the skew and kurtosis are likely to be large enough to measure. Even the single fluid element spectrum may exhibit measurable directional anisotropy, so that instruments with different lines of sight should see different yields, mean velocities, mean temperatures, and higher moments. Finally, we briefly discuss how scattering in the imploded core modifies the neutron spectrum by changing the relative weighting of fuel regions with different temperatures and velocities.

  15. Prospects for toroidal fusion reactors

    SciTech Connect

    Sheffield, J.; Galambos, J.D.

    1994-06-01

    Work on the International Thermonuclear Experimental Reactor (ITER) tokamak has refined understanding of the realities of a deuterium-tritium (D-T) burning magnetic fusion reactor. An ITER-like tokamak reactor using ITER costs and performance would lead to a cost of electricity (COE) of about 130 mills/kWh. Advanced tokamak physics to be tested in the Toroidal Physics Experiment (TPX), coupled with moderate components in engineering, technology, and unit costs, should lead to a COE comparable with best existing fission systems around 60 mills/kWh. However, a larger unit size, {approximately}2000 MW(e), is favored for the fusion system. Alternative toroidal configurations to the conventional tokamak, such as the stellarator, reversed-field pinch, and field-reversed configuration, offer some potential advantage, but are less well developed, and have their own challenges.

  16. Interplanetary propulsion using inertial fusion

    NASA Technical Reports Server (NTRS)

    Orth, C. D.; Hogan, W. J.; Hoffman, N.; Murray, K.; Klein, G.; Diaz, F. C.

    1987-01-01

    Inertial fusion can be used to power spacecraft within the solar system and beyond. Such spacecraft have the potential for short-duration manned-mission performance exceeding other technologies. We are conducting a study to assess the systems aspects of inertial fusion as applied to such missions, based on the conceptual engine design of Hyde (1983) we describe the required systems for an entirely new spacecraft design called VISTA that is based on the use of DT fuel. We give preliminary design details for the power conversion and power conditioning systems for manned missions to Mars of total duration of about 100 days. Specific mission performance results will be published elsewhere, after the study has been completed.

  17. Investigation of condensed matter fusion

    SciTech Connect

    Jones, S.E.; Berrondo, M.; Czirr, J.B.; Decker, D.L.; Harrison, K.; Jensen, G.L.; Palmer, E.P.; Rees, L.B.; Taylor, S.; Vanfleet, H.B.; Wang, J.C.; Bennion, D.N.; Harb, J.N.; Pitt, W.G.; Thorne, J.M.; Anderson, A.N.; McMurtry, G.; Murphy, N.; Goff, F.E.

    1990-12-01

    Work on muon-catalyzed fusion led to research on a possible new type of fusion occurring in hydrogen isotopes embedded in metal lattices. While the nuclear-product yields observed to date are so small as to require careful further checking, rates observed over short times appear sufficiently large to suggest that significant neutrons and triton yields could be realized -- if the process could be understood and controlled. During 1990, we have developed two charged-particle detection systems and three new neutron detectors. A segmented, high-efficiency neutron counter was taken into 600 m underground in a mine in Colorado for studies out of the cosmic-ray background. Significant neutron emissions were observed in this environment in both deuterium-gas-loaded metals and in electrolytic cells, confirming our earlier observations.

  18. Mirror fusion vacuum technology developments

    SciTech Connect

    Batzer, T.H.; Call, W.R.

    1983-11-21

    Magnetic Mirror Fusion experiments, such as MFTF-B+T (Mirror Fusion Test Facility-B, Tritium Upgrade) and foreseeable follow-on devices, have operational and maintenance requirements that have not yet been fully demonstrated. Among those associated with vacuum technology are the very-high continuous-pumping speeds, 10/sup 7/ to 10/sup 8/ l/s for D/sub 2/, T/sub 2/ and, to a lesser extent, He; the early detection of water leaks from the very-high heat-flux neutral-beam dumps and the detection and location of leaks in the superconducting magnets not protected by guard vacuums. Possible solutions to these problems have been identified and considerable progress has been made toward successfully demonstrating their feasibility.

  19. Neutron transport-burnup code MCORGS and its application in fusion fission hybrid blanket conceptual research

    NASA Astrophysics Data System (ADS)

    Shi, Xue-Ming; Peng, Xian-Jue

    2016-09-01

    Fusion science and technology has made progress in the last decades. However, commercialization of fusion reactors still faces challenges relating to higher fusion energy gain, irradiation-resistant material, and tritium self-sufficiency. Fusion Fission Hybrid Reactors (FFHR) can be introduced to accelerate the early application of fusion energy. Traditionally, FFHRs have been classified as either breeders or transmuters. Both need partition of plutonium from spent fuel, which will pose nuclear proliferation risks. A conceptual design of a Fusion Fission Hybrid Reactor for Energy (FFHR-E), which can make full use of natural uranium with lower nuclear proliferation risk, is presented. The fusion core parameters are similar to those of the International Thermonuclear Experimental Reactor. An alloy of natural uranium and zirconium is adopted in the fission blanket, which is cooled by light water. In order to model blanket burnup problems, a linkage code MCORGS, which couples MCNP4B and ORIGEN-S, is developed and validated through several typical benchmarks. The average blanket energy Multiplication and Tritium Breeding Ratio can be maintained at 10 and 1.15 respectively over tens of years of continuous irradiation. If simple reprocessing without separation of plutonium from uranium is adopted every few years, FFHR-E can achieve better neutronic performance. MCORGS has also been used to analyze the ultra-deep burnup model of Laser Inertial Confinement Fusion Fission Energy (LIFE) from LLNL, and a new blanket design that uses Pb instead of Be as the neutron multiplier is proposed. In addition, MCORGS has been used to simulate the fluid transmuter model of the In-Zinerater from Sandia. A brief comparison of LIFE, In-Zinerater, and FFHR-E will be given.

  20. Heavy Ion Fusion Injector Program

    SciTech Connect

    Yu, S.; Eylon, S.; Chupp, W.W.

    1993-05-01

    A program is underway to construct a 2 MV, 800 mA, K{sup +} injector for heavy ion fusion. The Electrostatic Quadrupole (ESQ) injector configuration consists of a zeolite source, a diode of up to 1 MV, together with several electrostatic quadrupole units to simultaneously focus and accelerate the beam to 2 MV. The key issues of source technology, high voltage breakdown, beam aberrations, and transient effects will be discussed. Results from ongoing experiments and simulations will be presented.

  1. FUSION WELDING METHOD AND APPARATUS

    DOEpatents

    Wyman, W.L.; Steinkamp, W.I.

    1961-01-17

    An apparatus for the fusion welding of metal pieces at a joint is described. The apparatus comprises a highvacuum chamber enclosing the metal pieces and a thermionic filament emitter. Sufficient power is applied to the emitter so that when the electron emission therefrom is focused on the joint it has sufficient energy to melt the metal pieces, ionize the metallic vapor abcve the molten metal, and establish an arc discharge between the joint and the emitter.

  2. Fusion for Earth and Space

    SciTech Connect

    Williams, Pharis E

    2009-03-16

    The compact reactor concept (Williams, 2007) has the potential to provide clean, safe and unlimited supply of energy for Earth and Space applications. The concept is a potential fusion reactor wherein deuterium nuclei are preferentially fused into helium nuclei. Because the deuterium nuclei are preferentially fused into helium nuclei at temperatures and energies lower than specified by the standard model there is no harmful radiation as a byproduct of this fusion process. Therefore, a reactor using this reaction does not need any shielding to contain such radiation. The energy released from each reaction and the absence of shielding makes the deuterium-plus-deuterium-to-helium (DDH) reactor very compact when compared to other reactors, both fission and fusion types. Moreover, the potential energy output per reactor weight and the absence of harmful radiation makes the DDH reactor an ideal candidate for individual home and space power. The concept also would make it possible for each plant or remote location to have it's own power source, on site, without the need for a connection to the power grid. This would minimize, or eliminate, power blackouts. The concept could replace large fission reactors and fossil fuel power plants plus provide energy for ships, locomotives, trucks and autos. It would make an ideal source of energy for space power applications and for space propulsion.

  3. Gasdynamic Mirror Fusion Propulsion Experiment

    NASA Technical Reports Server (NTRS)

    Emrich, William J., Jr.; Rodgers, Stephen L. (Technical Monitor)

    2001-01-01

    Nuclear fusion appears to be the most promising concept for producing extremely high specific impulse rocket engines. One particular fusion concept which seems to be particularly well suited for fusion propulsion applications is the gasdynamic mirror (GDM). This device would operate at much higher plasma densities and with much larger LD ratios than previous mirror machines. Several advantages accrue from such a design. First, the high LA:) ratio minimizes to a large extent certain magnetic curvature effects which lead to plasma instabilities causing a loss of plasma confinement. Second, the high plasma density will result in the plasma behaving much more Re a conventional fluid with a mean free path shorter than the length of the device. This characteristic helps reduce problems associated with "loss cone" microinstabilities. An experimental GDM device is currently being constructed at the NASA Marshall Space Flight Center to provide an initial assessment of the feasibility of this type of propulsion system. Initial experiments are expected to commence in the late fall of 2000.

  4. Fusion product measurements in tokamaks

    SciTech Connect

    Strachan, J.D.

    1985-05-01

    Diagnostic methods and the applications of fusion product measurements in tokamaks are reviewed with emphasis on results from PLT, PDX, and TFTR. Measurements have been made using the 2.5-MeV neutron from the d(d, n)/sup 3/ He reaction, the 3-MeV proton from the d(d, p)t reaction, both the 3.7-MeV alpha and the 14.7-MeV proton from the d(/sup 3/He, p)..cap alpha.. reaction, and the 14-MeV neutron from the d(t, n)..cap alpha.. reaction. The common use of these measurements is the determination of the ion temperature from the magnitude of the d-d neutron emission. For tokamak plasmas, these results are usually in good agreement with the charge exchange ion temperature. Recently, the charged fusion products have been used for high-resolution spectroscopic purposes, and emission profile measurements. Pitch angle resolution of the escaping 3-MeV proton emission has been used to determine the poloidal magnetic field inside the tokamak. Major issues in this field include the expected tritium operation on TFTR where the neutron measurements will determine when tritium will be introduced into the TFTR vessel and provide a measurement of the fusion power multiplication value (Q). The TFTR Q approx. 1 experiments will also provide a chance to measure the confinement of 3.5-MeV alphas in a tokamak.

  5. Observations of membrane fusion in a liposome dispersion: the missing fusion intermediate?

    PubMed Central

    Foldvari, Marianna

    2015-01-01

    Early intermediate structures of liposome-liposome fusion events were captured by freeze-fracture electron microscopic (EM) technique. The images show the morphology of the fusion interface at several different stages of the fusion event. One of the intermediates was captured at a serendipitous stage of two vesicles’ membranes (both leaflets) merging and their contents starting to intermix clearly showing the fusion interface with a previously unseen fusion rim. From the morphological information a hypothetical sequence of the fusion event and corresponding lipid structural arrangements are described. PMID:26069726

  6. Getting smarter about commercialization opportunities

    SciTech Connect

    Henderson, Pamela; McMakin, Andrea H.; Arnold, Todd

    2005-08-31

    The Disruptive Market Research method, pioneered by Dr. Pam Henderson of Meridian Strategies, helps technology developers make better commercialization decisions and find industry parters. More than 120 entrepreneurial organizations, ranging from the U.S. Department of Energy's Pacific Northwest National Laboratory to Fortune 500 firms, have used the method to evaluate the commercial potential of new products and to shape business strategies.

  7. Space Station commercial user development

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The commercial utilization of the space station is investigated. The interest of nonaerospace firms in the use of the space station is determined. The user requirements are compared to the space station's capabilities and a feasibility analysis of a commercial firm acting as an intermediary between NASA and the private sector to reduce costs is presented.

  8. Lessons learned: The commercialization process

    SciTech Connect

    Padilla, B.A.; Gritzo, R.E.; Garcia, J.J.

    1996-03-01

    One successful component of a commercialization strategy includes the implementation of an industrial outreach workshop. This workshop is designed to select an industrial partner with the skills necessary to successfully commercialize a federally-funded, laboratory developed technology. These workshops provide efficiency and effectiveness and, in addition, ensure that all prospective partners receive equal access to the same quality and quantity of information.

  9. Commercial researcher perspective

    NASA Astrophysics Data System (ADS)

    Delucas, Larry

    Protein crystallography--a research tool used to study the structure of the complex building blocks of living systems--has a lot to gain from space-based research. In order to know how a protein works in the human body, researchers must understand its molecular structure. Researchers have identified 150,000 different proteins in the body, but they now know the structure of less than a third of them. The only viable technique for analyzing the structure of these proteins is x-ray diffraction of the proteins in their crystal form. The better the quality of a protein crystal, the more useful it is to researchers who are trying to delineate its structure. The microgravity environment of space allows protein crystals to grow nearly undisturbed by convection and other gravity-driven forces that cause flaws to form in them on the ground. In space, lack of convection enables protein crystals to grow more slowly than they do on Earth, and the slower a protein crystal grows, the fewer flaws it will have. Protein crystal growth experiments have already flown on 14 Space Shuttle missions. This year's USML-1 Spacelab mission included protein crystal growth experiments conducted for commercial researchers. The results of protein crystal experiments flown thus far have been larger crystals with more uniform morphologies. The Center for Macromolecular Crystallography (A NASA-cosponsored CCDS) currently builds flight hardware to meet researchers' needs and handles sample loading and retrieval for flight experiments. Protein crystallography enables 'rational drug design': the development of drugs that bind only with the target protein and, hence, do not cause side effects. For example, pharmaceutical companies presently are interested in developing drugs that can inhibit purine nucleoside phosphorylase (PNP), a protein that plays a role in auto-immune diseases. To continue these kinds of investigations, researchers need a constant supply of protein crystals that are as free of flaws

  10. 150 Passenger Commercial Aircraft

    NASA Technical Reports Server (NTRS)

    Bucovsky, Adrian; Romli, Fairuz I.; Rupp, Jessica

    2002-01-01

    It has been projected that the need for a short-range mid-sized, aircraft is increasing. The future strategy to decrease long-haul flights will increase the demand for short-haul flights. Since passengers prefer to meet their destinations quickly, airlines will increase the frequency of flights, which will reduce the passenger load on the aircraft. If a point-to-point flight is not possible, passengers will prefer only a one-stop short connecting flight to their final destination. A 150-passenger aircraft is an ideal vehicle for these situations. It is mid-sized aircraft and has a range of 3000 nautical miles. This type of aircraft would market U.S. domestic flights or inter-European flight routes. The objective of the design of the 150-passenger aircraft is to minimize fuel consumption. The configuration of the aircraft must be optimized. This aircraft must meet CO2 and NOx emissions standards with minimal acquisition price and operating costs. This report contains all the work that has been performed for the completion of the design of a 150 passenger commercial aircraft. The methodology used is the Technology Identification, Evaluation, and Selection (TIES) developed at Georgia Tech Aerospace Systems Design laboratory (ASDL). This is an eight-step conceptual design process to evaluate the probability of meeting the design constraints. This methodology also allows for the evaluation of new technologies to be implemented into the design. The TIES process begins with defining the problem with a need established and a market targeted. With the customer requirements set and the target values established, a baseline concept is created. Next, the design space is explored to determine the feasibility and viability of the baseline aircraft configuration. If the design is neither feasible nor viable, new technologies can be implemented to open up the feasible design space and allow for a plausible solution. After the new technologies are identified, they must be evaluated

  11. Commercial researcher perspective

    NASA Technical Reports Server (NTRS)

    Delucas, Larry

    1992-01-01

    Protein crystallography--a research tool used to study the structure of the complex building blocks of living systems--has a lot to gain from space-based research. In order to know how a protein works in the human body, researchers must understand its molecular structure. Researchers have identified 150,000 different proteins in the body, but they now know the structure of less than a third of them. The only viable technique for analyzing the structure of these proteins is x-ray diffraction of the proteins in their crystal form. The better the quality of a protein crystal, the more useful it is to researchers who are trying to delineate its structure. The microgravity environment of space allows protein crystals to grow nearly undisturbed by convection and other gravity-driven forces that cause flaws to form in them on the ground. In space, lack of convection enables protein crystals to grow more slowly than they do on Earth, and the slower a protein crystal grows, the fewer flaws it will have. Protein crystal growth experiments have already flown on 14 Space Shuttle missions. This year's USML-1 Spacelab mission included protein crystal growth experiments conducted for commercial researchers. The results of protein crystal experiments flown thus far have been larger crystals with more uniform morphologies. The Center for Macromolecular Crystallography (A NASA-cosponsored CCDS) currently builds flight hardware to meet researchers' needs and handles sample loading and retrieval for flight experiments. Protein crystallography enables 'rational drug design': the development of drugs that bind only with the target protein and, hence, do not cause side effects. For example, pharmaceutical companies presently are interested in developing drugs that can inhibit purine nucleoside phosphorylase (PNP), a protein that plays a role in auto-immune diseases. To continue these kinds of investigations, researchers need a constant supply of protein crystals that are as free of flaws

  12. NASA's approach to space commercialization

    NASA Technical Reports Server (NTRS)

    Gillam, Isaac T., IV

    1986-01-01

    The NASA Office of Commercial Programs fosters private participation in commercially oriented space projects. Five Centers for the Commercial Development of Space encourage new ideas and perform research which may yield commercial processes and products for space ventures. Joint agreements allow companies who present ideas to NASA and provide flight hardware access to a free launch and return from orbit. The experimenters furnish NASA with sufficient data to demonstrate the significance of the results. Ground-based tests are arranged for smaller companies to test the feasibility of concepts before committing to the costs of developing hardware. Joint studies of mutual interest are performed by NASA and private sector researchers, and two companies have signed agreements for a series of flights in which launch costs are stretched out to meet projected income. Although Shuttle flights went on hold following the Challenger disaster, extensive work continues on the preparation of commercial research payloads that will fly when Shuttle flights resume.

  13. Fusion Nuclear Science Pathways Assessment

    SciTech Connect

    C.E. Kessel, et. al.

    2012-02-23

    With the strong commitment of the US to the success of the ITER burning plasma mission, and the project overall, it is prudent to consider how to take the most advantage of this investment. The production of energy from fusion has been a long sought goal, and the subject of several programmatic investigations and time line proposals [1]. The nuclear aspects of fusion research have largely been avoided experimentally for practical reasons, resulting in a strong emphasis on plasma science. Meanwhile, ITER has brought into focus how the interface between the plasma and engineering/technology, presents the most challenging problems for design. In fact, this situation is becoming the rule and no longer the exception. ITER will demonstrate the deposition of 0.5 GW of neutron heating to the blanket, deliver a heat load of 10-20 MW/m2 or more on the divertor, inject 50-100 MW of heating power to the plasma, all at the expected size scale of a power plant. However, in spite of this, and a number of other technologies relevant power plant, ITER will provide a low neutron exposure compared to the levels expected to a fusion power plant, and will purchase its tritium entirely from world reserves accumulated from decades of CANDU reactor operations. Such a decision for ITER is technically well founded, allowing the use of conventional materials and water coolant, avoiding the thick tritium breeding blankets required for tritium self-sufficiency, and allowing the concentration on burning plasma and plasma-engineering interface issues. The neutron fluence experienced in ITER over its entire lifetime will be ~ 0.3 MW-yr/m2, while a fusion power plant is expected to experience 120-180 MW-yr/m2 over its lifetime. ITER utilizes shielding blanket modules, with no tritium breeding, except in test blanket modules (TBM) located in 3 ports on the midplane [2], which will provide early tests of the fusion nuclear environment with very low tritium production (a few g per year).

  14. Materials issues in fusion reactors

    NASA Astrophysics Data System (ADS)

    Suri, A. K.; Krishnamurthy, N.; Batra, I. S.

    2010-02-01

    The world scientific community is presently engaged in one of the toughest technological tasks of the current century, namely, exploitation of nuclear fusion in a controlled manner for the benefit of mankind. Scientific feasibility of controlled fusion of the light elements in plasma under magnetic confinement has already been proven. International efforts in a coordinated and co-operative manner are presently being made to build ITER - the International Thermonuclear Experimental Reactor - to test, in this first step, the concept of 'Tokamak' for net fusion energy production. To exploit this new developing option of making energy available through the route of fusion, India too embarked on a robust fusion programme under which we now have a working tokamak - the Aditya and a steady state tokamak (SST-1), which is on the verge of functioning. The programme envisages further development in terms of making SST-2 followed by a DEMO and finally the fusion power reactor. Further, with the participation of India in the ITER program in 2005, and recent allocation of half - a - port in ITER for placing our Lead - Lithium Ceramic Breeder (LLCB) based Test Blanket Module (TBM), meant basically for breeding tritium and extracting high grade heat, the need to understand and address issues related to materials for these complex systems has become all the more necessary. Also, it is obvious that with increasing power from the SST stages to DEMO and further to PROTOTYPE, the increasing demands on performance of materials would necessitate discovery and development of new materials. Because of the 14.1 MeV neutrons that are generated in the D+T reaction exploited in a tokamak, the materials, especially those employed for the construction of the first wall, the diverter and the blanket segments, suffer crippling damage due to the high He/dpa ratios that result due to the high energy of the neutrons. To meet this challenge, the materials that need to be developed for the tokamaks

  15. Imaging multiple intermediates of single-virus membrane fusion mediated by distinct fusion proteins.

    PubMed

    Joo, Kye-Il; Tai, April; Lee, Chi-Lin; Wong, Clement; Wang, Pin

    2010-09-01

    Membrane fusion plays an essential role in the entry of enveloped viruses into target cells. The merging of viral and target cell membranes is catalyzed by viral fusion proteins, which involves multiple sequential steps in the fusion process. However, the fusion mechanisms mediated by different fusion proteins involve multiple transient intermediates that have not been well characterized. Here, we report a synthetic virus platform that allows us to better understand the different fusion mechanisms driven by the diverse types fusion proteins. The platform consists of lentiviral particles coenveloped with a surface antibody, which serves as the binding protein, along with a fusion protein derived from either influenza virus (HAmu) or Sindbis virus (SINmu). By using a single virus tracking technique, we demonstrated that both HAmu- and SINmu-bearing viruses enter cells through clathrin-dependent endocytosis, but they required different endosomal trafficking routes to initiate viral fusion. Direct observation of single viral fusion events clearly showed that hemifusion mediated by SINmu upon exposure to low pH occurs faster than that mediated by HAmu. Monitoring sequential fusion processes by dual labeling the outer and inner leaflets of viral membranes also revealed that the SINmu-mediated hemifusion intermediate is relatively long-lived as compared with that mediated by HAmu. Taken together, we have demonstrated that the combination of this versatile viral platform with the techniques of single virus tracking can be a powerful tool for revealing molecular details of fusion mediated by various fusion proteins.

  16. Study of fusion Q-value rule in sub-barrier fusion of heavy ions

    NASA Astrophysics Data System (ADS)

    Liu, Xing-Xing; Zhang, Gao-Long; Zhang, Huan-Qiao

    2015-07-01

    A vast body of fusion data has been analyzed for different projectiles and target nuclei. It is indicated that the sub-barrier fusion depends on the fusion Q-value. In terms of a recently introduced fusion Q-value rule and an energy scaling reduction procedure, the experimental fusion excitation functions are reduced and compared with each other. It is found that the reduced fusion excitations of selected fusion systems show a similar trend. The fusion data for massive nuclei are in agreement with the Q-value rule. In the fusion process, the Q contribution should be considered. Within this approach, the sub-barrier fusion cross sections of most fusion systems can be predicted without involving any structure effects of colliding nuclei. Instances of disagreement are presented in a few fusion systems. The use of the energy scaling as a criterion of possible experimental data inconsistency is discussed. More precise experimental fusion data need to be measured. Supported by National Nature Science Foundation of China (11475013, 11035007, 11175011), State Key Laboratory of Software Development Environment (SKLSDE-2014ZX-08), Fundamental Research Funds for the Central Universities and the Key Laboratory of High Precision Nuclear Spectroscopy, Institute of Modern Physics, Chinese Academy of Sciences

  17. The lateral clavicular epiphysis: fusion timing and age estimation.

    PubMed

    Langley, Natalie R

    2016-03-01

    This study utilizes a forensic autopsy sample of twentieth century American Whites (the McCormick Clavicle Collection) to describe the morphology, variation, and fusion timing of the lateral clavicle epiphysis. Clavicles from individuals between 11 and 25 years at the time of death were used to document fusion of the lateral epiphysis (n= 133, 38 females and 95 males). The lateral epiphysis was scored as unfused, fusing, or fused. A linear weighted kappa indicates that this scoring method is highly replicable with almost perfect inter-rater agreement (kappa = 0.849), according to a widely used standard for assessing kappa values. Transition analysis, or probit regression, was employed to quantify fusion timing of the lateral epiphysis. The transition from "unfused" to "fusing" is most likely to occur at 16.5 years in females and 17.5 years in males. The transition from "fusing" to "fused" occurs at age 21 in females and age 20 in males. The earliest age at which fusion began was 15 years (n = 1), but the majority began fusing between 17 and 20 years. Most individuals (98.5 % of the sample) aged >24 years had fused lateral epiphyses. The epiphysis assumes one of two forms: (1) a separate bony flake fusing to the diaphysis or (2) a mound of bone glazing/smoothing over the diaphyseal surface. As socioeconomic status has been cited as the most influential variable on skeletal maturation rates, the fusion ages offered here should not be applied to populations with a socioeconomic status different from the greater US population.

  18. Nuclear Fusion Award 2009 speech Nuclear Fusion Award 2009 speech

    NASA Astrophysics Data System (ADS)

    Sabbagh, Steven Anthony

    2011-01-01

    This is an exceptional moment in my career, and so I want to thank all of my teachers, colleagues and mentors who have made this possible. From my co-authors and myself, many thanks to the International Atomic Energy Agency, IOP Publishing, the Nuclear Fusion journal team, and the selection committee for the great honor of receiving this award. Also gratitude to Kikuchi-sensei, not only for the inventive and visionary creation of this award, but also for being a key mentor dating back to his efforts in producing high neutron output in JT-60U. It was also a great honor to receive the award directly from IAEA Deputy Director General Burkart during the 23rd IAEA Fusion Energy Conference in Daejeon. Receiving the award at this venue is particularly exciting as Daejeon is home to the new, next-generation KSTAR tokamak device that will lead key magnetic fusion research areas going forward. I would also like to thank the mayor of Daejeon, Dr Yum Hong-Chul, and all of the meeting organizers for giving us all a truly spectacular and singular welcoming event during which the award was presented. The research leading to the award would not have been possible without the support of the US Department of Energy, and I thank the Department for the continued funding of this research. Special mention must be made to a valuable co-author who is no longer with us, Professor A. Bondeson, who was a significant pioneer in resistive wall mode (RWM) research. I would like to thank my wife, Mary, for her infinite patience and encouragement. Finally, I would like to personally thank all of you that have approached and congratulated me directly. There are no units to measure how important your words have been in this regard. When notified that our paper had been shortlisted for the 2009 Nuclear Fusion Award, my co-authors responded echoing how I felt—honored to be included in such a fine collection of research by colleagues. It was unfathomable—would this paper follow the brilliant work

  19. Influence of breakup on fusion barrier distributions

    NASA Astrophysics Data System (ADS)

    Patel, D.; Nayak, B. K.; Mukherjee, S.; Biswas, D. C.; Mirgule, E. T.; John, B. V.; Gupta, Y. K.; Mukhopadhyay, S.; Prajapati, G.; Danu, L. S.; Rath, P. K.; Desai, V.; Deshmukh, N.; Saxena, A.

    2013-04-01

    Fusion barrier distributions have been extracted from the quasi-elastic scattering excitation functions, measured at backward angle θlab = 160° in reactions of 6,7Li+209Bi. The present results have been compared with the barrier distributions obtained from the fusion excitation function measurements for the above mentioned systems. The fusion barrier distributions from the quasi-elastic scattering excitation functions have been analyzed with simplified Coupled Channels calculations using Fresco. Inclusions of resonant states for both 6,7Li projectiles improve the predictions to describe the measured quasi-elastic scattering excitation functions and barrier distributions. For both the reactions peak positions of fusion barrier distributions are shifted towards a lower energy side in comparison to that obtained from the fusion excitation function measurements. The observed discrepancy in peak positions of barrier distributions obtained from quasi-elastic scattering and fusion excitation function measurements has been discussed in terms of total reaction threshold distribution.

  20. The Dark Side of Cell Fusion

    PubMed Central

    Bastida-Ruiz, Daniel; Van Hoesen, Kylie; Cohen, Marie

    2016-01-01

    Cell fusion is a physiological cellular process essential for fertilization, viral entry, muscle differentiation and placental development, among others. In this review, we will highlight the different cancer cell-cell fusions and the advantages obtained by these fusions. We will specially focus on the acquisition of metastatic features by cancer cells after fusion with bone marrow-derived cells. The mechanism by which cancer cells fuse with other cells has been poorly studied thus far, but the presence in several cancer cells of syncytin, a trophoblastic fusogen, leads us to a cancer cell fusion mechanism similar to the one used by the trophoblasts. The mechanism by which cancer cells perform the cell fusion could be an interesting target for cancer therapy. PMID:27136533

  1. Conceptual exploration package for data fusion

    NASA Astrophysics Data System (ADS)

    Jousselme, Anne-Laure; Grenier, Dominic; Bosse, Eloi

    2000-04-01

    In this paper, we present a software package designed to explore data fusion area applied to different contexts. This tool, called CEPfuse (Conceptual Exploration Package for Data Fusion) provides a good support to become familiar with all concepts and vocabulary linked to data fusion. Developed with Matlab 5.2, it's also a good tool to test, compare and analyze algorithms. Although the core of this package is evidential reasoning and identity information fusion, it has been conceived to develop all the interesting part of the Multi-Sensor Data Fusion system. Actually, because we concentrate our research work on identity information fusion, the principal included algorithms are Dempster- Shafer rules of combination, Shafer-Logan algorithms for hierarchical structures, and several decision rules.

  2. Is Fusion Inhibited for Weakly Bound Nuclei?

    SciTech Connect

    Takahashi, J.; Munhoz, M.; Szanto, E.M.; Carlin, N.; Added, N.; Suaide, A.A.; de Moura, M.M.; Liguori Neto, R.; Szanto de Toledo, A.; Canto, L.F.

    1997-01-01

    Complete fusion of light radioactive nuclei is predicted to be hindered at near-barrier energies. This feature is investigated in the case of the least bound stable nuclei. Evaporation residues resulting from the {sup 6,7}Li+{sup 9}Be and {sup 6,7}Li+{sup 12}C fusion reactions have been measured in order to study common features in reactions involving light weakly bound nuclei. The experimental excitation functions revealed that the fusion cross section is significantly smaller than the total reaction cross section and also smaller than the fusion cross section expected from the available systematics. A clear correlation between the fusion probability and nucleon (cluster) separation energy has been established.The results suggest that the breakup process has a strong influence on the hindrance of the fusion cross section. {copyright} {ital 1996} {ital The American Physical Society}

  3. Incomplete fusion dynamics by spin distribution measurements

    SciTech Connect

    Singh, D.; Ali, R.; Ansari, M. Afzal; Singh, Pushpendra P.; Sharma, M. K.; Singh, B. P.; Babu, K. Surendra; Sinha, Rishi K.; Kumar, R.; Muralithar, S.; Singh, R. P.; Bhowmik, R. K.

    2010-02-15

    Spin distributions for various evaporation residues populated via complete and incomplete fusion of {sup 16}O with {sup 124}Sn at 6.3 MeV/nucleon have been measured, using charged particles (Z=1,2)-{gamma} coincidence technique. Experimentally measured spin distributions of the residues produced as incomplete fusion products associated with 'fast'{alpha}- and 2{alpha}-emission channels observed in the 'forward cone' are found to be distinctly different from those of the residues produced as complete fusion products. Moreover, 'fast'{alpha}-particles that arise from larger angular momentum in the entrance channel are populated at relatively higher driving input angular momentum than those produced through complete fusion. The incomplete fusion residues are populated in a limited, higher-angular-momentum range, in contrast to the complete fusion products, which are populated over a broad spin range.

  4. Inertial-confinement fusion with lasers

    NASA Astrophysics Data System (ADS)

    Betti, R.; Hurricane, O. A.

    2016-05-01

    The quest for controlled fusion energy has been ongoing for over a half century. The demonstration of ignition and energy gain from thermonuclear fuels in the laboratory has been a major goal of fusion research for decades. Thermonuclear ignition is widely considered a milestone in the development of fusion energy, as well as a major scientific achievement with important applications in national security and basic sciences. The US is arguably the world leader in the inertial confinement approach to fusion and has invested in large facilities to pursue it, with the objective of establishing the science related to the safety and reliability of the stockpile of nuclear weapons. Although significant progress has been made in recent years, major challenges still remain in the quest for thermonuclear ignition via laser fusion. Here, we review the current state of the art in inertial confinement fusion research and describe the underlying physical principles.

  5. History of Nuclear Fusion Research in Japan

    NASA Astrophysics Data System (ADS)

    Iguchi, Harukazu; Matsuoka, Keisuke; Kimura, Kazue; Namba, Chusei; Matsuda, Shinzaburo

    In the late 1950s just after the atomic energy research was opened worldwide, there was a lively discussion among scientists on the strategy of nuclear fusion research in Japan. Finally, decision was made that fusion research should be started from the basic, namely, research on plasma physics and from cultivation of human resources at universities under the Ministry of Education, Science and Culture (MOE). However, an endorsement was given that construction of an experimental device for fusion research would be approved sooner or later. Studies on toroidal plasma confinement started at Japan Atomic Energy Research Institute (JAERI) under the Science and Technology Agency (STA) in the mid-1960s. Dualistic fusion research framework in Japan was established. This structure has lasted until now. Fusion research activities over the last 50 years are described by the use of a flowchart, which is convenient to glance the historical development of fusion research in Japan.

  6. Reprogramming of somatic cells induced by fusion of embryonic stem cells using hemagglutinating virus of Japan envelope (HVJ-E)

    SciTech Connect

    Yue, Xiao-shan; Fujishiro, Masako; Toyoda, Masashi; Akaike, Toshihiro; Ito, Yoshihiro

    2010-04-16

    In this research, hemagglutinating virus of Japan envelope (HVJ-E) was used to reprogram somatic cells by fusion with mouse embryonic stem (ES) cells. Neomycin-resistant mouse embryonic fibroblasts (MEFs) were used as somatic cells. Nanog-overexpressing puromycin-resistant EB3 cells were used as mouse ES cells. These two cells were fused by exposing to HVJ-E and the generated fusion cells were selected by puromycin and G418 to get the stable fusion cell line. The fusion cells form colonies in feeder-free culture system. Microsatellite analysis of the fusion cells showed that they possessed genes from both ES cells and fibroblasts. The fusion cells were tetraploid, had alkali phosphatase activity, and expressed stem cell marker genes such as Pou5f1, Nanog, and Sox2, but not the fibroblast cell marker genes such as Col1a1 and Col1a2. The pluripotency of fusion cells was confirmed by their expression of marker genes for all the three germ layers after differentiation induction, and by their ability to form teratoma which contained all the three primary layers. Our results show that HVJ-E can be used as a fusion reagent for reprogramming of somatic cells.

  7. Recurrent fusion transcripts detected by whole-transcriptome sequencing of 120 primary breast cancer samples.

    PubMed

    Kim, Jisun; Kim, Sehwan; Ko, Seyoon; In, Yong-ho; Moon, Hyeong-Gon; Ahn, Soo Kyung; Kim, Min Kyoon; Lee, Minju; Hwang, Jin-Ha; Ju, Young Seok; Kim, Jong-Il; Noh, Dong-Young; Kim, Sun; Park, Jung-Hoon; Rhee, Hwanseok; Kim, Sunghoon; Han, Wonshik

    2015-11-01

    Relatively few recurrent gene fusion events have been associated with breast cancer to date. In an effort to uncover novel fusion transcripts, we performed whole-transcriptome sequencing of 120 fresh-frozen primary breast cancer samples and five adjacent normal breast tissues using the Illumina HiSeq2000 platform. Three different fusion-detecting tools (deFuse, Chimerascan, and TopHatFusion) were used, and the results were compared. These tools detected 3,831, 6,630 and 516 fusion transcripts (FTs) overall. We primarily focused on the results obtained using the deFuse software. More FTs were identified from HER2 subtype breast cancer samples than from the luminal or triple-negative subtypes (P < 0.05). Seventy fusion candidates were selected for validation, and 32 (45.7%) were confirmed by RT-PCR and Sanger sequencing. Of the validated fusions, six were recurrent (found in 2 or more samples), three were in-frame (PRDX1-AKR1A1, TACSTD2-OMA1, and C2CD2-TFF1) and three were off-frame (CEACAM7-CEACAM6, CYP4X1-CYP4Z2P, and EEF1DP3-FRY). Notably, the novel read-through fusion, EEF1DP3-FRY, was identified and validated in 6.7% (8/120) of the breast cancer samples. This off-frame fusion results in early truncation of the FRY gene, which plays a key role in the structural integrity during mitosis. Three previously reported fusions, PPP1R1B-STARD3, MFGE8-HAPL, and ETV6-NTRK3, were detected in 8.3, 3.3, and 0.8% of the 120 samples, respectively, by both deFuse and Chimerascan. The recently reported MAGI3-AKT3 fusion was not detected in our analysis. Although future work will be needed to examine the biological significance of our new findings, we identified a number of novel fusions and confirmed some previously reported fusions. PMID:26227178

  8. Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion

    NASA Astrophysics Data System (ADS)

    Yang, Sung-Tae; Kiessling, Volker; Tamm, Lukas K.

    2016-04-01

    Lipids and proteins are organized in cellular membranes in clusters, often called `lipid rafts'. Although raft-constituent ordered lipid domains are thought to be energetically unfavourable for membrane fusion, rafts have long been implicated in many biological fusion processes. For the case of HIV gp41-mediated membrane fusion, this apparent contradiction can be resolved by recognizing that the interfaces between ordered and disordered lipid domains are the predominant sites of fusion. Here we show that line tension at lipid domain boundaries contributes significant energy to drive gp41-fusion peptide-mediated fusion. This energy, which depends on the hydrophobic mismatch between ordered and disordered lipid domains, may contribute tens of kBT to fusion, that is, it is comparable to the energy required to form a lipid stalk intermediate. Line-active compounds such as vitamin E lower line tension in inhomogeneous membranes, thereby inhibit membrane fusion, and thus may be useful natural viral entry inhibitors.

  9. Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion.

    PubMed

    Yang, Sung-Tae; Kiessling, Volker; Tamm, Lukas K

    2016-01-01

    Lipids and proteins are organized in cellular membranes in clusters, often called 'lipid rafts'. Although raft-constituent ordered lipid domains are thought to be energetically unfavourable for membrane fusion, rafts have long been implicated in many biological fusion processes. For the case of HIV gp41-mediated membrane fusion, this apparent contradiction can be resolved by recognizing that the interfaces between ordered and disordered lipid domains are the predominant sites of fusion. Here we show that line tension at lipid domain boundaries contributes significant energy to drive gp41-fusion peptide-mediated fusion. This energy, which depends on the hydrophobic mismatch between ordered and disordered lipid domains, may contribute tens of kBT to fusion, that is, it is comparable to the energy required to form a lipid stalk intermediate. Line-active compounds such as vitamin E lower line tension in inhomogeneous membranes, thereby inhibit membrane fusion, and thus may be useful natural viral entry inhibitors. PMID:27113279

  10. Adaptive sensor fusion using genetic algorithms

    SciTech Connect

    Fitzgerald, D.S.; Adams, D.G.

    1994-08-01

    Past attempts at sensor fusion have used some form of Boolean logic to combine the sensor information. As an alteniative, an adaptive ``fuzzy`` sensor fusion technique is described in this paper. This technique exploits the robust capabilities of fuzzy logic in the decision process as well as the optimization features of the genetic algorithm. This paper presents a brief background on fuzzy logic and genetic algorithms and how they are used in an online implementation of adaptive sensor fusion.

  11. An Alternate Development Path for Magnetic Fusion

    NASA Astrophysics Data System (ADS)

    Manheimer, Wallace

    2001-12-01

    Mid-century requirements for carbon free energy are daunting. Perhaps fusion could play a vital role. One of rather few possible solutions for sustainable development might be the fission fusion hybrid coupled with transmutation of the long lived actinide wastes. This paper suggests such an alternate development path for fusion, one that could lead to the production of multi-terawatts of carbon free power by 2050.

  12. Plasma Physics and Controlled Nuclear Fusion

    NASA Astrophysics Data System (ADS)

    Fisch, N. J.

    2010-01-01

    Already while making his famous contributions in uncontrolled nuclear fusion for wartime uses, Edward Teller contemplated how the abundant energy release through nuclear fusion might serve peacetime uses as well. His legacy in controlled nuclear fusion, and the associated physics of plasmas, spans both magnetic and inertial confinement approaches. His contributions in plasma physics, both the intellectual and the administrative, continue to impact the field.

  13. Review of alternative concepts for magnetic fusion

    SciTech Connect

    Krakowski, R.A.; Miller, R.L.; Hagenson, R.L.

    1980-01-01

    Although the Tokamak represents the mainstay of the world's quest for magnetic fusion power, with the tandem mirror serving as a primary backup concept in the US fusion program, a wide range of alternative fusion concepts (AFC's) have been and are being pursued. This review presents a summary of past and present reactor projections of a majority of AFC's. Whenever possible, quantitative results are given.

  14. Indirect drive targets for fusion power

    DOEpatents

    Amendt, Peter A.; Miles, Robin R.

    2016-10-11

    A hohlraum for an inertial confinement fusion power plant is disclosed. The hohlraum includes a generally cylindrical exterior surface, and an interior rugby ball-shaped surface. Windows over laser entrance holes at each end of the hohlraum enclose inert gas. Infrared reflectors on opposite sides of the central point reflect fusion chamber heat away from the capsule. P2 shields disposed on the infrared reflectors help assure an enhanced and more uniform x-ray bath for the fusion fuel capsule.

  15. This is Commercial Titan, Inc

    NASA Astrophysics Data System (ADS)

    van Rensselaer, F. L.; Slovikoski, R. D.; Abels, T. C.

    1989-10-01

    Out of a quarter-century heritage of eminently successful expendable launch vehicle history with the U.S government, a commercial launch services enterprise which challenges the corporation as well as the competition has been launched within the Martin Marietta Corporation. This paper is an inside look at the philosophy, structure, and success of the new subsidiary, Commercial Titan, Inc., which is taking on its U.S. and foreign rocket-making competitors to win a share of the international communication satellite market as well as the U.S. government commercial launch services market.

  16. Pilot production & commercialization of LAPPD™

    NASA Astrophysics Data System (ADS)

    Minot, Michael J.; Bennis, Daniel C.; Bond, Justin L.; Craven, Christopher A.; O`Mahony, Aileen; Renaud, Joseph M.; Stochaj, Michael E.; Elam, Jeffrey W.; Mane, Anil U.; Demarteau, Marcellinus W.; Wagner, Robert G.; McPhate, Jason B.; Helmut Siegmund, Oswald; Elagin, Andrey; Frisch, Henry J.; Northrop, Richard; Wetstein, Matthew J.

    2015-07-01

    We present a progress update on plans to establish pilot production and commercialization of Large Area (400 cm2) Picosecond Photodetector (LAPPD™). Steps being taken to commercialize this MCP and LAPPD™ technology and begin tile pilot production are presented including (1) the manufacture of 203 mm×203 mm borosilicate glass capillary arrays (GCAs), (2) optimization of MCP performance and creation of an ALD coating facility to manufacture MCPs and (3) design, construction and commissioning of UHV tile integration and sealing facility to produce LAPPDs. Taken together these plans provide a "pathway toward commercialization".

  17. Mitochondrial Fusion Is Essential for Steroid Biosynthesis

    PubMed Central

    Cooke, Mariana; Soria, Gastón; Cornejo Maciel, Fabiana; Gottifredi, Vanesa; Podestá, Ernesto J.

    2012-01-01

    Although the contribution of mitochondrial dynamics (a balance in fusion/fission events and changes in mitochondria subcellular distribution) to key biological process has been reported, the contribution of changes in mitochondrial fusion to achieve efficient steroid production has never been explored. The mitochondria are central during steroid synthesis and different enzymes are localized between the mitochondria and the endoplasmic reticulum to produce the final steroid hormone, thus suggesting that mitochondrial fusion might be relevant for this process. In the present study, we showed that the hormonal stimulation triggers mitochondrial fusion into tubular-shaped structures and we demonstrated that mitochondrial fusion does not only correlate-with but also is an essential step of steroid production, being both events depend on PKA activity. We also demonstrated that the hormone-stimulated relocalization of ERK1/2 in the mitochondrion, a critical step during steroidogenesis, depends on mitochondrial fusion. Additionally, we showed that the SHP2 phosphatase, which is required for full steroidogenesis, simultaneously modulates mitochondrial fusion and ERK1/2 localization in the mitochondrion. Strikingly, we found that mitofusin 2 (Mfn2) expression, a central protein for mitochondrial fusion, is upregulated immediately after hormone stimulation. Moreover, Mfn2 knockdown is sufficient to impair steroid biosynthesis. Together, our findings unveil an essential role for mitochondrial fusion during steroidogenesis. These discoveries highlight the importance of organelles’ reorganization in specialized cells, prompting the exploration of the impact that organelle dynamics has on biological processes that include, but are not limited to, steroid synthesis. PMID:23029265

  18. Fusion Concept Exploration Experiments at PPPL

    SciTech Connect

    Stewart Zweben; Samuel Cohen; Hantao Ji; Robert Kaita; Richard Majeski; Masaaki Yamada

    1999-05-01

    Small ''concept exploration'' experiments have for many years been an important part of the fusion research program at the Princeton Plasma Physics Laboratory (PPPL). this paper describes some of the present and planned fusion concept exploration experiments at PPPL. These experiments are a University-scale research level, in contrast with the larger fusion devices at PPPL such as the National Spherical Torus Experiment (NSTX) and the Tokamak Fusion Test Reactor (TFTR), which are at ''proof-of-principle'' and ''proof-of-performance'' levels, respectively.

  19. Mitochondrial fusion is essential for steroid biosynthesis.

    PubMed

    Duarte, Alejandra; Poderoso, Cecilia; Cooke, Mariana; Soria, Gastón; Cornejo Maciel, Fabiana; Gottifredi, Vanesa; Podestá, Ernesto J

    2012-01-01

    Although the contribution of mitochondrial dynamics (a balance in fusion/fission events and changes in mitochondria subcellular distribution) to key biological process has been reported, the contribution of changes in mitochondrial fusion to achieve efficient steroid production has never been explored. The mitochondria are central during steroid synthesis and different enzymes are localized between the mitochondria and the endoplasmic reticulum to produce the final steroid hormone, thus suggesting that mitochondrial fusion might be relevant for this process. In the present study, we showed that the hormonal stimulation triggers mitochondrial fusion into tubular-shaped structures and we demonstrated that mitochondrial fusion does not only correlate-with but also is an essential step of steroid production, being both events depend on PKA activity. We also demonstrated that the hormone-stimulated relocalization of ERK1/2 in the mitochondrion, a critical step during steroidogenesis, depends on mitochondrial fusion. Additionally, we showed that the SHP2 phosphatase, which is required for full steroidogenesis, simultaneously modulates mitochondrial fusion and ERK1/2 localization in the mitochondrion. Strikingly, we found that mitofusin 2 (Mfn2) expression, a central protein for mitochondrial fusion, is upregulated immediately after hormone stimulation. Moreover, Mfn2 knockdown is sufficient to impair steroid biosynthesis. Together, our findings unveil an essential role for mitochondrial fusion during steroidogenesis. These discoveries highlight the importance of organelles' reorganization in specialized cells, prompting the exploration of the impact that organelle dynamics has on biological processes that include, but are not limited to, steroid synthesis.

  20. Fusion development and technology. Technical progress report, October 15, 1990--October 14, 1993

    SciTech Connect

    Montgomery, D.B.

    1992-06-01

    This report discusses the following: superconducting magnet technology; high field superconductors; advanced magnetic system and divertor development; poloidal field coils; gyrotron development; commercial reactor studies--aries; ITER physics: alpha physics and alcator R&D for ITER; lower hybrid current drive and heating in the ITER device; ITER superconducting PF scenario and magnet analysis; ITER systems studies; and safety, environmental and economic factors in fusion development.

  1. Nuclear Fusion Award 2010 speech Nuclear Fusion Award 2010 speech

    NASA Astrophysics Data System (ADS)

    Rice, John

    2011-01-01

    Following the suggestion of Earl Marmar in 1995, I installed a compact von Hamos type x-ray spectrometer (originally built with Elisabeth Rachlew and Jan Kallne) on a tangentially viewing port on the Alcator C-Mod tokamak. The spectrometer views the plasma through a 2 cm diameter hole, and is tuned to H-like argon, suitable for passive measurement of the core toroidal rotation velocity from the Doppler shift. It soon became evident that the rotation in Ohmic L-mode discharges, while for the most part directed counter-current, depends in a very complicated fashion on plasma parameters, notably the electron density, current and magnetic configuration. The rotation can even flip sign for almost no apparent reason! In Ohmic and ion cyclotron range of frequencies (ICRF) heated H-mode plasmas the rotation is in the co-current direction and has a relatively simple dependence on plasma parameters, proportional to the stored energy normalized to the current. Rotation velocities as high as 130 km s-1 have been observed without external momentum input. In dimensionless terms this intrinsic (or spontaneous rotation) depends on the normalized plasma pressure. The association of toroidal rotation with plasma pressure in ICRF H-modes was first observed by Lars-Goran Eriksson in JET discharges. Similar results were subsequently reported for Tore Supra enhanced confinement plasmas. In the early 2000s concerns began to surface about the lack of substantial neutral beam driven rotation in ITER, and intrinsic rotation became a topic of interest in the ITPA Transport Group. Through that connection, similar observations from DIII-D, TCV and JT-60U were added to the growing list. A database of intrinsic rotation observations was assembled with the goal of extrapolating to the expected values for ITER. Both dimensional and dimensionless scalings were developed and formed the backbone of the 2007 Nuclear Fusion paper. I gratefully acknowledge the important contributions to this paper from

  2. Interplanetary propulsion using inertial fusion

    NASA Technical Reports Server (NTRS)

    Orth, Charles D.; Hoffman, Nate; Murray, Kathy; Klein, Gail; Diaz, Franklin Chang

    1987-01-01

    Inertial fusion can be used to power spacecraft within the solar system and beyond. Such spacecraft have the potential for short duration manned mission performance exceeding other technologies. A study was conducted to assess the systems aspects of inertial as applied to such missions, based on the conceptual engine design of Hyde (1983). The required systems for an entirely new spacecraft design called VISTA that is based on the use of DT fuel is described. Preliminary design details are given for the power conversion and power conditioning systems for manned missions to Mars of total duration of about 100 days.

  3. Modular stellarator fusion reactor concept

    NASA Astrophysics Data System (ADS)

    Miller, R. L.; Krakowski, R. A.

    1981-08-01

    A steady-state ignited, DT-fueled, magnetic fusion reactor is proposed for use as a central electric-power station. The MSR concept combines the physics of the classic stellarator confinement topology with an innovative, modular-coil design. Parametric tradeoff calculations are described, leading to the selection of an interim design point for a 4-GWt plant based on Alcator transport scaling and an average beta value of 0.04 in an 1 = 2 system with a plasma aspect ratio of 11. The physical basis of the design point is described together with supporting magnetics, coil-force, and stress computations.

  4. Tokamak Diagnostics Using Fusion Products.

    NASA Astrophysics Data System (ADS)

    Heidbrink, William Walter

    Measurements of neutrons and protons produced by the d(d,n)('3)He, d(t,n)(alpha), d(d,p)t, and d(('3)He,p)(alpha) fusion reactions are used to diagnose plasmas in the PLT and PDX tokamaks. An expression for the efficiency of proton detection is derived and confirmed experimentally. The time evolution of the ('3)He density indicates that a scoop limiter may pump ('3)He from the plasma faster than conventional limiters. The confinement of 1.0 MeV tritons and of 0.8 MeV ('3)He ions is studied by measuring the fraction of these fusion-produced ions that burn up in subsequent fusion reactions. In discharges with sawtooth activity and with B(,(phi)) > 2 T, the triton and ('3)He 'burnup' is consistent (within a factor of three) with predictions based on classical theories of ion confinement and slowing down. In discharges with large m = 2 or fishbone instabilities, the ('3)He burnup is less than classically predicted and, in PLT discharges at B(,(phi)) = 1.8 T, the triton burnup is over an order of magnitude smaller than predicted. Expressions for the energy spectrum of ions produced in beam-target fusion reactions are derived. Collimated measurements of the spectrum of 15 MeV protons produced by reactions between energetic ('3)He ions and relatively cold deuterons during fast wave minority heating indicate that the velocity distribution of fast ('3)He ions is peaked perpendicular to the tokamak magnetic field. The ion temperature profile and density of fast deuterons are measured with an array of collimated 3 MeV proton detectors. The fast ions produced by neutral beam injection and by launching lower hybrid waves are concentrated near the magnetic axis. Poloidal field measurements using 3 MeV protons also appear possible. In discharges in which the line radiation from central impurities does not decay, the plasma current profile is broader than in more typical discharges.

  5. Thomson scattering at general fusion

    NASA Astrophysics Data System (ADS)

    Young, W. C.; Parfeniuk, D.

    2016-11-01

    This paper provides an overview of the Thomson scattering diagnostic in use at General Fusion, including recent upgrades and upcoming plans. The plasma experiment under examination produces temperatures in the 50-500 eV range with density on the order of 1020 m-3. A four spatial point collection optics scheme has been implemented, with plans to expand to six spatial points. Recent changes to the optics of the laser beamline have reduced stray light. The system employs a frequency doubled Nd:YAG laser (532 nm), a grating spectrometer, and a photomultiplier array based detector.

  6. Laser fusion pulse shape controller

    DOEpatents

    Siebert, Larry D.

    1977-01-01

    An apparatus for controlling the pulse shape, i.e., the pulse duration and intensity pattern, of a pulsed laser system, and which is particularly well adapted for controlling the pellet ignition pulse in a laser-driven fusion reaction system. The apparatus comprises a laser generator for providing an optical control pulse of the shape desired, a pulsed laser triggered by the control pulse, and a plurality of optical Kerr-effect gates serially disposed at the output of the pulsed laser and selectively triggered by the control pulse to pass only a portion of the pulsed laser output generally corresponding in shape to the control pulse.

  7. Multisensor Fusion for Change Detection

    NASA Astrophysics Data System (ADS)

    Schenk, T.; Csatho, B.

    2005-12-01

    Combining sensors that record different properties of a 3-D scene leads to complementary and redundant information. If fused properly, a more robust and complete scene description becomes available. Moreover, fusion facilitates automatic procedures for object reconstruction and modeling. For example, aerial imaging sensors, hyperspectral scanning systems, and airborne laser scanning systems generate complementary data. We describe how data from these sensors can be fused for such diverse applications as mapping surface erosion and landslides, reconstructing urban scenes, monitoring urban land use and urban sprawl, and deriving velocities and surface changes of glaciers and ice sheets. An absolute prerequisite for successful fusion is a rigorous co-registration of the sensors involved. We establish a common 3-D reference frame by using sensor invariant features. Such features are caused by the same object space phenomena and are extracted in multiple steps from the individual sensors. After extracting, segmenting and grouping the features into more abstract entities, we discuss ways on how to automatically establish correspondences. This is followed by a brief description of rigorous mathematical models suitable to deal with linear and area features. In contrast to traditional, point-based registration methods, lineal and areal features lend themselves to a more robust and more accurate registration. More important, the chances to automate the registration process increases significantly. The result of the co-registration of the sensors is a unique transformation between the individual sensors and the object space. This makes spatial reasoning of extracted information more versatile; reasoning can be performed in sensor space or in 3-D space where domain knowledge about features and objects constrains reasoning processes, reduces the search space, and helps to make the problem well-posed. We demonstrate the feasibility of the proposed multisensor fusion approach

  8. Introduction to Nuclear Fusion Power and the Design of Fusion Reactors. An Issue-Oriented Module.

    ERIC Educational Resources Information Center

    Fillo, J. A.

    This three-part module focuses on the principles of nuclear fusion and on the likely nature and components of a controlled-fusion power reactor. The physical conditions for a net energy release from fusion and two approaches (magnetic and inertial confinement) which are being developed to achieve this goal are described. Safety issues associated…

  9. Commercialization in NASA Space Operations

    NASA Technical Reports Server (NTRS)

    Gilbert, Charlene E.

    1998-01-01

    Various issues associated with commercialization in NASA space operations are presented in viewgraph form. Specific topics include: 1) NASA's financial outlook; 2) Space operations; 3) Space operations technology; and 4) Strategies associated with these operations.

  10. The Seasat commercial demonstration program

    NASA Technical Reports Server (NTRS)

    Mccandless, S. W.; Miller, B. P.; Montgomery, D. R.

    1981-01-01

    The background and development of the Seasat commercial demonstration program are reviewed and the Seasat spacecraft and its sensors (altimeter, wind field scatterometer, synthetic aperture radar, and scanning multichannel microwave radiometer) are described. The satellite data distribution system allows for selected sets of data, reformatted or tailored to specific needs and geographical regions, to be available to commercial users. Products include sea level and upper atmospheric pressure, sea surface temperature, marine winds, significant wave heights, primary wave direction and period, and spectral wave data. The results of a set of retrospective case studies performed for the commercial demonstration program are described. These are in areas of application such as marine weather and ocean condition forecasting, offshore resource exploration and development, commercial fishing, and marine transportation.

  11. Commercialization of parabolic dish systems

    NASA Technical Reports Server (NTRS)

    Washom, B.

    1982-01-01

    The impact of recent federal tax and regulatory legislation on the commercialization of parabolic solar reflector technology is assessed. Specific areas in need of technical or economic improvement are noted.

  12. Commercialization of parabolic dish systems

    NASA Astrophysics Data System (ADS)

    Washom, B.

    1982-07-01

    The impact of recent federal tax and regulatory legislation on the commercialization of parabolic solar reflector technology is assessed. Specific areas in need of technical or economic improvement are noted.

  13. Commercial Crew Planning Status Forum

    NASA Video Gallery

    NASA presents an overview of common themes captured from industry responses provided to NASA's Commercial Crew Initiative Request for Information (RFI) published on May 21, 2010. The forum includes...

  14. Multiexposure and multifocus image fusion with multidimensional camera shake compensation

    NASA Astrophysics Data System (ADS)

    Gomez, Alexis Lluis; Saravi, Sara; Edirisinghe, Eran A.

    2013-10-01

    Multiexposure image fusion algorithms are used for enhancing the perceptual quality of an image captured by sensors of limited dynamic range. This is achieved by rendering a single scene based on multiple images captured at different exposure times. Similarly, multifocus image fusion is used when the limited depth of focus on a selected focus setting of a camera results in parts of an image being out of focus. The solution adopted is to fuse together a number of multifocus images to create an image that is focused throughout. A single algorithm that can perform both multifocus and multiexposure image fusion is proposed. This algorithm is a new approach in which a set of unregistered multiexposure/focus images is first registered before being fused to compensate for the possible presence of camera shake. The registration of images is done via identifying matching key-points in constituent images using scale invariant feature transforms. The random sample consensus algorithm is used to identify inliers of SIFT key-points removing outliers that can cause errors in the registration process. Finally, the coherent point drift algorithm is used to register the images, preparing them to be fused in the subsequent fusion stage. For the fusion of images, a new approach based on an improved version of a wavelet-based contourlet transform is used. The experimental results and the detailed analysis presented prove that the proposed algorithm is capable of producing high-dynamic range (HDR) or multifocus images by registering and fusing a set of multiexposure or multifocus images taken in the presence of camera shake. Further, comparison of the performance of the proposed algorithm with a number of state-of-the art algorithms and commercial software packages is provided. In particular, our literature review has revealed that this is one of the first attempts where the compensation of camera shake, a very likely practical problem that can result in HDR image capture using

  15. Rethinking "Commercial" Surrogacy in Australia.

    PubMed

    Millbank, Jenni

    2015-09-01

    This article proposes reconsideration of laws prohibiting paid surrogacy in Australia in light of increasing transnational commercial surrogacy. The social science evidence base concerning domestic surrogacy in developed economies demonstrates that payment alone cannot be used to differentiate "good" surrogacy arrangements from "bad" ones. Compensated domestic surrogacy and the introduction of professional intermediaries and mechanisms such as advertising are proposed as a feasible harm-minimisation approach. I contend that Australia can learn from commercial surrogacy practices elsewhere, without replicating them. PMID:25015592

  16. Rethinking "Commercial" Surrogacy in Australia.

    PubMed

    Millbank, Jenni

    2015-09-01

    This article proposes reconsideration of laws prohibiting paid surrogacy in Australia in light of increasing transnational commercial surrogacy. The social science evidence base concerning domestic surrogacy in developed economies demonstrates that payment alone cannot be used to differentiate "good" surrogacy arrangements from "bad" ones. Compensated domestic surrogacy and the introduction of professional intermediaries and mechanisms such as advertising are proposed as a feasible harm-minimisation approach. I contend that Australia can learn from commercial surrogacy practices elsewhere, without replicating them.

  17. Satellite image fusion based on principal component analysis and high-pass filtering.

    PubMed

    Metwalli, Mohamed R; Nasr, Ayman H; Allah, Osama S Farag; El-Rabaie, S; Abd El-Samie, Fathi E

    2010-06-01

    This paper presents an integrated method for the fusion of satellite images. Several commercial earth observation satellites carry dual-resolution sensors, which provide high spatial resolution or simply high-resolution (HR) panchromatic (pan) images and low-resolution (LR) multi-spectral (MS) images. Image fusion methods are therefore required to integrate a high-spectral-resolution MS image with a high-spatial-resolution pan image to produce a pan-sharpened image with high spectral and spatial resolutions. Some image fusion methods such as the intensity, hue, and saturation (IHS) method, the principal component analysis (PCA) method, and the Brovey transform (BT) method provide HR MS images, but with low spectral quality. Another family of image fusion methods, such as the high-pass-filtering (HPF) method, operates on the basis of the injection of high frequency components from the HR pan image into the MS image. This family of methods provides less spectral distortion. In this paper, we propose the integration of the PCA method and the HPF method to provide a pan-sharpened MS image with superior spatial resolution and less spectral distortion. The experimental results show that the proposed fusion method retains the spectral characteristics of the MS image and, at the same time, improves the spatial resolution of the pan-sharpened image. PMID:20508708

  18. Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products.

    PubMed Central

    Harlow, E; Franza, B R; Schley, C

    1985-01-01

    Hybridomas secreting monoclonal antibodies specific for the adenovirus early region 1A (E1A) proteins were prepared from BALB/c mice immunized with a bacterial trpE-E1A fusion protein. This protein is encoded by a hybrid gene that joins a portion of the Escherichia coli trpE gene and a cDNA copy of the E1A 13S mRNA (Spindler et al., J. Virol. 49:132-141, 1984). Eighty-three hybridomas that secrete antibodies which recognize the immunogen were isolated and single cell cloned. Twenty-nine of these antibodies are specific for the E1A portion of the fusion protein. Only 12 of the monoclonal antibodies can efficiently immunoprecipitate E1A polypeptides from detergent lysates of infected cells. E1A polypeptides were analyzed on one-dimensional, sodium dodecyl sulfate-polyacrylamide gels and two-dimensional, isoelectric focusing polyacrylamide gels. The E1A proteins that are specifically immunoprecipitated by the monoclonal antibodies are heterogeneous in size and charge and can be resolved into approximately 60 polypeptide species. This heterogeneity is due not only to synthesis from multiple E1A mRNAs, but also at least in part to post-translational modification. Several of the monoclonal antibodies divide the E1A polypeptides into immunological subclasses based on the ability of the antibodies to bind to the antigen. In particular, two of the monoclonal antibodies bind to the polypeptides synthesized from the 13S E1A mRNA, but not to other E1A proteins. Images PMID:3894685

  19. Magnetized Target Fusion Driven by Plasma Liners

    NASA Technical Reports Server (NTRS)

    Thio, Y. C. Francis; Kirkpatrick, Ronald C.; Knapp, Charles E.; Rodgers, Stephen L. (Technical Monitor)

    2002-01-01

    Magnetized target fusion is an emerging, relatively unexplored approach to fusion for electrical power and propulsion application. The physical principles of the concept are founded upon both inertial confinement fusion (ICF) and magnetic confinement fusion (MCF). It attempts to combine the favorable attributes of both these orthogonal approaches to fusion, but at the same time, avoiding the extreme technical challenges of both by exploiting a fusion regime intermediate between them. It uses a material liner to compress, heat and contain the fusion reacting plasma (the target plasma) mentally. By doing so, the fusion burn could be made to occur at plasma densities as high as six orders of magnitude higher than conventional MCF such as tokamak, thus leading to an approximately three orders of magnitude reduction in the plasma energy required for ignition. It also uses a transient magnetic field, compressed to extremely high intensity (100's T to 1000T) in the target plasma, to slow down the heat transport to the liner and to increase the energy deposition of charged-particle fusion products. This has several compounding beneficial effects. It leads to longer energy confinement time compared with conventional ICF without magnetized target, and thus permits the use of much lower plasma density to produce reasonable burn-up fraction. The compounding effects of lower plasma density and the magneto-insulation of the target lead to greatly reduced compressional heating power on the target. The increased energy deposition rate of charged-particle fusion products also helps to lower the energy threshold required for ignition and increasing the burn-up fraction. The reduction in ignition energy and the compressional power compound to lead to reduced system size, mass and R&D cost. It is a fusion approach that has an affordable R&D pathway, and appears attractive for propulsion application in the nearer term.

  20. Experiments in predictive sensor fusion

    NASA Astrophysics Data System (ADS)

    Keller, James M.; Auephanwiriyakul, Sansanee; Gader, Paul D.

    2001-10-01

    Data fusion is a process of combining evidence from different information sources in order to make a better judgement. However, multiple sources can provide complementary information that can be used to increase the performance in detection and recognition. There are many frameworks within which to combine these pieces into a more meaningful answer. However, new information added might be redundant or even conflicting with the existing information. These questions arise: can we predict the value added by fusing their outputs together, if we know the general characteristics of a set of sensors. Can we specify the needed characteristics of a new sensor/algorithm to add to an existing suite to gain a desired improvement performance. The characteristic of a new sensor can be in any forms, e.g., the ratio of a target's signal to the clutter's signal, the position resolution etc. In this paper, we consider these questions in the context of fuzzy set theory and in particular, a soft decision level fusion scheme we developed for land mine detection scenarios. Here, we primarily consider the ratio of a target's signal. We develop a tool to estimate a final d-metric when the information form several sensor is fused through the linguistic Choquet fuzzy integral. We utilize this tool in the examination of the performance of d-metrics in a simulation environment. The approach is demonstrated for data obtained from an Advanced Technology Demonstration in vehicle-based mine detection.

  1. Large excimer lasers for fusion

    SciTech Connect

    Jensen, R.J.

    1986-01-01

    Important goals in DOE and DOD programs require multimegajoule laser pulses. For inertial confinement fusion there is also a requirement to deliver the pulse in about 25 nsec with a very particular power vs time profile - all at high overall efficiency and low cost per joule. After exhaustive consideration of various alternatives, our studies have shown that the most cost effective approach to energy scaling is to increase the size of the final amplifiers up to the 200 to 300 kJ level. This conclusion derives largely from the fact that, at a given complexity, costs increase slowly with increasing part size while output energy should increase dramatically. Extrapolations to low cost by drastic cuts in the unit cost of smaller devices through mass production are considered highly risky. At a minimum the requirement to provide, space, optics and mounts for such systems will remain expensive. In recent years there have been dramatic advances in scaling. The Los Alamos LAM has produced over 10 kJ in a single 1/2 nsec pulse. In this paper we explore the issues involved in scaling to higher energy while still maintaining high efficiencies. In the remainder of this paper we will discuss KrF laser scaling for the fusion mission. We will omit most of the discussion of the laser system design, but address only KrF amplifiers.

  2. Technical Letter Report - Preliminary Assessment of NDE Methods on Inspection of HDPE Butt Fusion Piping Joints for Lack of Fusion

    SciTech Connect

    Crawford, Susan L.; Cumblidge, Stephen E.; Doctor, Steven R.; Hall, Thomas E.; Anderson, Michael T.

    2008-05-29

    was conducted. Millimeter (mm) waves were also used to inspect these assemblies. Fluor and NDE Innovations, Inc. conducted TOFD inspections using their commercially available equipment on all 24 specimens. These NDE inspection results were reviewed and several of the specimens were selected for destructive evaluation using a microtome to slice small blocks of blank and fusion joint material. This interim report provides a status/summary of the work that has been conducted to date. In the areas selected for destructive testing where there were strong acoustic responses, LOF was verified. In areas where there were no NDE responses, no LOF was found. It needs to be noted that only a small amount of material has been destructively characterized at this point and further work is planned to determine if these trends hold up. Some of the material from three of the assemblies was sent off for mechanical testing but the results were not available to be included in this status report. The initial work shows that at least some of the LOF is providing NDE responses that have been verified through destructive testing. Thus, there is promise that a volumetric examination can be conducted on HDPE butt fusion joints. The future work will lead to quantifying what various NDE methods can detect, what they miss, and what they incorrectly characterize as defective.

  3. Commercializing fuel cells: managing risks

    NASA Astrophysics Data System (ADS)

    Bos, Peter B.

    Commercialization of fuel cells, like any other product, entails both financial and technical risks. Most of the fuel cell literature has focussed upon technical risks, however, the most significant risks during commercialization may well be associated with the financial funding requirements of this process. Successful commercialization requires an integrated management of these risks. Like any developing technology, fuel cells face the typical 'Catch-22' of commercialization: "to enter the market, the production costs must come down, however, to lower these costs, the cumulative production must be greatly increased, i.e. significant market penetration must occur". Unless explicit steps are taken to address this dilemma, fuel cell commercialization will remain slow and require large subsidies for market entry. To successfully address this commercialization dilemma, it is necessary to follow a market-driven commercialization strategy that identifies high-value entry markets while minimizing the financial and technical risks of market entry. The financial and technical risks of fuel cell commercialization are minimized, both for vendors and end-users, with the initial market entry of small-scale systems into high-value stationary applications. Small-scale systems, in the order of 1-40 kW, benefit from economies of production — as opposed to economies to scale — to attain rapid cost reductions from production learning and continuous technological innovation. These capital costs reductions will accelerate their commercialization through market pull as the fuel cell systems become progressively more viable, starting with various high-value stationary and, eventually, for high-volume mobile applications. To facilitate market penetration via market pull, fuel cell systems must meet market-derived economic and technical specifications and be compatible with existing market and fuels infrastructures. Compatibility with the fuels infrastructure is facilitated by a

  4. Computer Modeling of a Fusion Plasma

    SciTech Connect

    Cohen, B I

    2000-12-15

    Progress in the study of plasma physics and controlled fusion has been profoundly influenced by dramatic increases in computing capability. Computational plasma physics has become an equal partner with experiment and traditional theory. This presentation illustrates some of the progress in computer modeling of plasma physics and controlled fusion.

  5. Application of polarized nuclei to fusion

    SciTech Connect

    Kulsrud, R.M.

    1987-07-01

    It is shown that the d-t fusion reaction can be modified by polarizing nuclear spins. The ways in which this improves reactor performance are mentioned and the feasibility of the process of spin polarization for magnetic fusion is discussed. 18 refs.

  6. Plasma physics and controlled thermonuclear fusion

    SciTech Connect

    Krikorian, R. )

    1989-01-01

    This proceedings contains papers on plasma physics and controlled thermonuclear fusion. Included are the following topics: Plasma focus and Z-pinch, Review of mirror fusion research, Progress in studies of x-ray and ion-beam emission from plasma focus facilities.

  7. Plasmas are Hot and Fusion is Cool

    SciTech Connect

    2011-01-01

    Plasmas are Hot and Fusion is Cold. The DOE Princeton Plasma Physics Laboratory (PPPL) collaborates to develop fusion as a safe, clean and abundant energy source for the future. This video discusses PPPL's research and development on plasma, the fourth state of matter.

  8. Method of controlling fusion reaction rates

    DOEpatents

    Kulsrud, Russell M.; Furth, Harold P.; Valeo, Ernest J.; Goldhaber, Maurice

    1988-01-01

    A method of controlling the reaction rates of the fuel atoms in a fusion reactor comprises the step of polarizing the nuclei of the fuel atoms in a particular direction relative to the plasma confining magnetic field. Fusion reaction rates can be increased or decreased, and the direction of emission of the reaction products can be controlled, depending on the choice of polarization direction.

  9. Method of controlling fusion reaction rates

    DOEpatents

    Kulsrud, Russell M.; Furth, Harold P.; Valeo, Ernest J.; Goldhaber, Maurice

    1988-03-01

    A method of controlling the reaction rates of the fuel atoms in a fusion reactor comprises the step of polarizing the nuclei of the fuel atoms in a particular direction relative to the plasma confining magnetic field. Fusion reaction rates can be increased or decreased, and the direction of emission of the reaction products can be controlled, depending on the choice of polarization direction.

  10. Mass Producing Targets for Nuclear Fusion

    NASA Technical Reports Server (NTRS)

    Wang, T. G.; Elleman, D. D.; Kendall, J. M.

    1983-01-01

    Metal-encapsulating technique advances prospects of controlling nuclear fusion. Prefilled fusion targets form at nozzle as molten metal such as tin flows through outer channel and pressurized deuterium/tritium gas flows through inner channel. Molten metal completely encloses gas charge as it drops off nozzle.

  11. Controlled Nuclear Fusion: Status and Outlook

    ERIC Educational Resources Information Center

    Rose, David J.

    1971-01-01

    Presents the history, current concerns and potential developments of nuclear fusion as a major energy source. Controlled fusion research is summarized, technological feasibility is discussed and environmental factors are examined. Relationships of alternative energy sources as well as energy utilization are considered. (JM)

  12. Fusion Propulsion Z-Pinch Engine Concept

    NASA Technical Reports Server (NTRS)

    Miernik, J.; Statham, G.; Fabisinski, L.; Maples, C. D.; Adams, R.; Polsgrove, T.; Fincher, S.; Cassibry, J.; Cortez, R.; Turner, M.; Percy, T.

    2011-01-01

    Fusion-based nuclear propulsion has the potential to enable fast interplanetary transportation. Due to the great distances between the planets of our solar system and the harmful radiation environment of interplanetary space, high specific impulse (Isp) propulsion in vehicles with high payload mass fractions must be developed to provide practical and safe vehicles for human spaceflight missions. The Z-Pinch dense plasma focus method is a Magneto-Inertial Fusion (MIF) approach that may potentially lead to a small, low cost fusion reactor/engine assembly1. Recent advancements in experimental and theoretical understanding of this concept suggest favorable scaling of fusion power output yield 2. The magnetic field resulting from the large current compresses the plasma to fusion conditions, and this process can be pulsed over short timescales (10(exp -6 sec). This type of plasma formation is widely used in the field of Nuclear Weapons Effects testing in the defense industry, as well as in fusion energy research. A Decade Module 2 (DM2), approx.500 KJ pulsed-power is coming to the RSA Aerophysics Lab managed by UAHuntsville in January, 2012. A Z-Pinch propulsion concept was designed for a vehicle based on a previous fusion vehicle study called "Human Outer Planet Exploration" (HOPE), which used Magnetized Target Fusion (MTF) 3 propulsion. The reference mission is the transport of crew and cargo to Mars and back, with a reusable vehicle.

  13. Socio-economic Aspects of Fusion

    SciTech Connect

    J.A. Schmidt

    2004-10-21

    Fusion power systems, if developed and deployed, would have many attractive features including power production not dependant on weather or solar conditions, flexible siting, and minimal carbon dioxide production. In this paper, we quantify the benefit of these features. In addition, fusion deployment scenarios are developed for the last half of this century and these scenarios are analyzed for resource requirements and waste production.

  14. The social evolution of somatic fusion.

    PubMed

    Aanen, Duur K; Debets, Alfons J M; de Visser, J Arjan G M; Hoekstra, Rolf F

    2008-11-01

    The widespread potential for somatic fusion among different conspecific multicellular individuals suggests that such fusion is adaptive. However, because recognition of non-kin (allorecognition) usually leads to a rejection response, successful somatic fusion is limited to close kin. This is consistent with kin-selection theory, which predicts that the potential cost of fusion and the potential for somatic parasitism decrease with increasing relatedness. Paradoxically, however, Crozier found that, in the short term, positive-frequency-dependent selection eliminates the required genetic polymorphism at allorecognition loci. The 'Crozier paradox' may be solved if allorecognition is based on extrinsically balanced polymorphisms, for example at immune loci. Alternatively, the assumption of most models that self fusion is mutually beneficial is wrong. If fusion is on average harmful, selection will promote unconditional rejection. However, we propose that fusion within individuals is beneficial, selecting for the ability to fuse, but fusion between individuals on average costly, selecting for non-self recognition (rather than non-kin recognition). We discuss experimental data on fungi that are consistent with this hypothesis. PMID:18937373

  15. Fusion breeder: its potential role and prospects

    SciTech Connect

    Lee, J.D.

    1981-01-01

    The fusion breeder is a concept that utilizes 14 MeV neutrons from D + T ..-->.. n(14.1 MeV) + ..cap alpha..(3.5 MeV) fusion reactions to produce more fuel than the tritium (T) needed to sustain the fusion process. This excess fuel production capacity is used to produce fissile material (Pu-239 or U-233) for subsequent use in fission reactors. We are concentrating on a class of blankets we call fission suppressed. The blanket is the region surrounding the fusion plasma in which fusion neutrons interact to produce fuel and heat. The fission-suppressed blanket uses non-fission reactions (mainly (n,2n) or (n,n't)) to generate excess neutrons for the production of net fuel. This is in contrast to the fast fission class of blankets which use (n,fiss) reactions to generate excess neutrons. Fusion reactors with fast fission blankets are commony known as fusion-fission hybrids because they combine fusion and fission in the same device.

  16. [La(3+)-induced fusion of plant protoplasts].

    PubMed

    Sheremet'ev, Iu A; Smirnova, D V; Sheremet'eva, A V

    2009-01-01

    The effect of La(3+) on the fusion of plant protoplasts has been studied. It was shown that La(3+) induced the aggregation of plant protoplasts. The incubation of a suspension of aggregated protoplasts at 42 degrees C for 30 min resulted in their fusion.

  17. National Ignition Facility for Inertial Confinement Fusion

    SciTech Connect

    Paisner, J.A.; Murray, J.R.

    1997-10-08

    The National Ignition Facility for inertial confinement fusion will contain a 1.8 MJ, 500 TW frequency-tripled neodymium glass laser system that will be used to explore fusion ignition and other problems in the physics of high temperature and density. We describe the facility briefly. The NIF is scheduled to be completed in 2003.

  18. Fluidized wall for protecting fusion chamber walls

    SciTech Connect

    Maniscalco, J.A.; Meier, W.R.

    1982-08-17

    Apparatus for protecting the inner wall of a fusion chamber from microexplosion debris, x-rays, neutrons, etc. Produced by deuterium-tritium (DT) targets imploded within the fusion chamber. The apparatus utilizes a fluidized wall similar to a waterfall comprising liquid lithium or solid pellets of lithiumceramic, the waterfall forming a blanket to prevent damage of the structural materials of the chamber.

  19. Fusion research: the past is prologue

    SciTech Connect

    Post, R F

    1998-10-14

    At this juncture fusion research can be viewed as being at a turning point, a time to review its past and to imagine its future. Today, almost 50 years since the first serious attempts to address the daunting problem of achieving controlled fusion, we have both an opportunity and a challenge. Some predictions place fusion research today at a point midway between its first inception and its eventual maturation - in the middle of the 21st century - when fusion would become a major source of energy. Our opportunity therefore is to assess what we have learned from 50 years of hard work and use that knowledge as a starting point for new and better approaches to solving the fusion problem. Our challenge is to prove the "50 more years" prophesy wrong, by finding ways to shorten the time when fusion power becomes a reality. The thesis will be advanced that in the magnetic confinement approach to fusion open-ended magnetic confinement geometries offer much in responding to the challenge. A major advantage of open systems is that, owing to their theoretically and experimentally demonstrated ability to suppress plasma instabilities of both the MHD and the high-frequency wave-particle variety, the confinement becomes predictable from "classical," i.e., Fokker-Planck-type analysis. In a time of straitened budgetary circumstances for magnetic fusion research now being faced in the United States, the theoretical tractability of mirror-based systems is a substantial asset. In pursuing this avenue it is also necessary to keep an open mind as to the forms that mirror-based fusion power plants might take. For example, one can look to the high-energy physics community for a possible model: This community has shown the feasibility of constructing large and complex particle accelerators using superconducting magnets, vacuum chambers and complicated particle-handling technology, housed in underground tunnels that are 20 or more kilometers long. In the paper examples of mirror

  20. The fusion diagnostic gamma experiment: A high-bandwidth fusion diagnostic of the National Ignition Facility

    SciTech Connect

    Moran, M.J.

    1999-01-01

    Diagnostics for the National Ignition Facility/inertial confinement fusion program must include good characterization of the fusion source. Ideally, diagnostics would measure the spatially resolved history of the fusion reaction rate and temperature. Existing diagnostics can satisfy this goal only partially. One class of new techniques that could play a major role in high-yield diagnostics is measurements based on fusion {gamma} rays. The fusion diagnostic gamma experiment can perform energy-resolved measurements of (D,T) fusion reaction rates. This diagnostic is based on the 16.7 MeV {gamma} rays that are produced by (D,T) fusion. The {gamma} rays are free of spectral dispersion and can be detected (via Compton recoil electrons) with a high bandwidth Cherenkov detector. A simple magnetic monochromator selects signals from the 16.7 MeV {gamma} rays and reduces background signals from nonfusion {gamma} rays. {copyright} {ital 1998 American Institute of Physics.}

  1. Estimating the melting point, entropy of fusion, and enthalpy of fusion of organic compounds via SPARC.

    PubMed

    Whiteside, T S; Hilal, S H; Brenner, A; Carreira, L A

    2016-08-01

    The entropy of fusion, enthalpy of fusion, and melting point of organic compounds can be estimated through three models developed using the SPARC (SPARC Performs Automated Reasoning in Chemistry) platform. The entropy of fusion is modelled through a combination of interaction terms and physical descriptors. The enthalpy of fusion is modelled as a function of the entropy of fusion, boiling point, and flexibility of the molecule. The melting point model is the enthalpy of fusion divided by the entropy of fusion. These models were developed in part to improve SPARC's vapour pressure and solubility models. These models have been tested on 904 unique compounds. The entropy model has a RMS of 12.5 J mol(-1) K(-1). The enthalpy model has a RMS of 4.87 kJ mol(-1). The melting point model has a RMS of 54.4°C. PMID:27586365

  2. Estimating the melting point, entropy of fusion, and enthalpy of fusion of organic compounds via SPARC.

    PubMed

    Whiteside, T S; Hilal, S H; Brenner, A; Carreira, L A

    2016-08-01

    The entropy of fusion, enthalpy of fusion, and melting point of organic compounds can be estimated through three models developed using the SPARC (SPARC Performs Automated Reasoning in Chemistry) platform. The entropy of fusion is modelled through a combination of interaction terms and physical descriptors. The enthalpy of fusion is modelled as a function of the entropy of fusion, boiling point, and flexibility of the molecule. The melting point model is the enthalpy of fusion divided by the entropy of fusion. These models were developed in part to improve SPARC's vapour pressure and solubility models. These models have been tested on 904 unique compounds. The entropy model has a RMS of 12.5 J mol(-1) K(-1). The enthalpy model has a RMS of 4.87 kJ mol(-1). The melting point model has a RMS of 54.4°C.

  3. Inertial-confinement fusion with lasers

    DOE PAGES

    Betti, R.; Hurricane, O. A.

    2016-05-03

    The quest for controlled fusion energy has been ongoing for over a half century. The demonstration of ignition and energy gain from thermonuclear fuels in the laboratory has been a major goal of fusion research for decades. Thermonuclear ignition is widely considered a milestone in the development of fusion energy, as well as a major scientific achievement with important applications to national security and basic sciences. The U.S. is arguably the world leader in the inertial con fment approach to fusion and has invested in large facilities to pursue it with the objective of establishing the science related to themore » safety and reliability of the stockpile of nuclear weapons. Even though significant progress has been made in recent years, major challenges still remain in the quest for thermonuclear ignition via laser fusion.« less

  4. Feature fusion based on Wootters metric

    NASA Astrophysics Data System (ADS)

    Peng, Weimin; Chen, Aihong; Gong, Zhaozhe

    2016-10-01

    For further enhancing the completeness and conciseness of the existing quantum-inspired feature fusion methods, this paper applies the quantum-related theories of Wootters metric and Fisher linear discriminant to dimension reduction and feature fusion. From the perspective of quantum metric spaces, i.e. phase space and probability space, this paper proposes two different feature fusion methods which take the Wootters statistical distance as the key factor to detect and fuse the duplicate feature data, and are different to the already developed quantum-inspired feature fusion methods. The experimental results reflect the superiority of the proposed feature fusion methods based on the Wootters metric for their better performances on relative completeness and conciseness.

  5. Cancer Cell Fusion: Mechanisms Slowly Unravel

    PubMed Central

    Noubissi, Felicite K.; Ogle, Brenda M.

    2016-01-01

    Although molecular mechanisms and signaling pathways driving invasion and metastasis have been studied for many years, the origin of the population of metastatic cells within the primary tumor is still not well understood. About a century ago, Aichel proposed that cancer cell fusion was a mechanism of cancer metastasis. This hypothesis gained some support over the years, and recently became the focus of many studies that revealed increasing evidence pointing to the possibility that cancer cell fusion probably gives rise to the metastatic phenotype by generating widespread genetic and epigenetic diversity, leading to the emergence of critical populations needed to evolve resistance to the treatment and development of metastasis. In this review, we will discuss the clinical relevance of cancer cell fusion, describe emerging mechanisms of cancer cell fusion, address why inhibiting cancer cell fusion could represent a critical line of attack to limit drug resistance and to prevent metastasis, and suggest one new modality for doing so. PMID:27657058

  6. Laser-fusion rocket for interplanetary propulsion

    SciTech Connect

    Hyde, R.A.

    1983-09-27

    A rocket powered by fusion microexplosions is well suited for quick interplanetary travel. Fusion pellets are sequentially injected into a magnetic thrust chamber. There, focused energy from a fusion Driver is used to implode and ignite them. Upon exploding, the plasma debris expands into the surrounding magnetic field and is redirected by it, producing thrust. This paper discusses the desired features and operation of the fusion pellet, its Driver, and magnetic thrust chamber. A rocket design is presented which uses slightly tritium-enriched deuterium as the fusion fuel, a high temperature KrF laser as the Driver, and a thrust chamber consisting of a single superconducting current loop protected from the pellet by a radiation shield. This rocket can be operated with a power-to-mass ratio of 110 W gm/sup -1/, which permits missions ranging from occasional 9 day VIP service to Mars, to routine 1 year, 1500 ton, Plutonian cargo runs.

  7. A Reliability-Based Track Fusion Algorithm

    PubMed Central

    Xu, Li; Pan, Liqiang; Jin, Shuilin; Liu, Haibo; Yin, Guisheng

    2015-01-01

    The common track fusion algorithms in multi-sensor systems have some defects, such as serious imbalances between accuracy and computational cost, the same treatment of all the sensor information regardless of their quality, high fusion errors at inflection points. To address these defects, a track fusion algorithm based on the reliability (TFR) is presented in multi-sensor and multi-target environments. To improve the information quality, outliers in the local tracks are eliminated at first. Then the reliability of local tracks is calculated, and the local tracks with high reliability are chosen for the state estimation fusion. In contrast to the existing methods, TFR reduces high fusion errors at the inflection points of system tracks, and obtains a high accuracy with less computational cost. Simulation results verify the effectiveness and the superiority of the algorithm in dense sensor environments. PMID:25950174

  8. Magnetic-fusion energy and computers

    SciTech Connect

    Killeen, J.

    1982-01-01

    The application of computers to magnetic fusion energy research is essential. In the last several years the use of computers in the numerical modeling of fusion systems has increased substantially. There are several categories of computer models used to study the physics of magnetically confined plasmas. A comparable number of types of models for engineering studies are also in use. To meet the needs of the fusion program, the National Magnetic Fusion Energy Computer Center has been established at the Lawrence Livermore National Laboratory. A large central computing facility is linked to smaller computer centers at each of the major MFE laboratories by a communication network. In addition to providing cost effective computing services, the NMFECC environment stimulates collaboration and the sharing of computer codes among the various fusion research groups.

  9. Fusion-protein-assisted protein crystallization.

    PubMed

    Kobe, Bostjan; Ve, Thomas; Williams, Simon J

    2015-07-01

    Fusion proteins can be used directly in protein crystallization to assist crystallization in at least two different ways. In one approach, the `heterologous fusion-protein approach', the fusion partner can provide additional surface area to promote crystal contact formation. In another approach, the `fusion of interacting proteins approach', protein assemblies can be stabilized by covalently linking the interacting partners. The linker connecting the proteins plays different roles in the two applications: in the first approach a rigid linker is required to reduce conformational heterogeneity; in the second, conversely, a flexible linker is required that allows the native interaction between the fused proteins. The two approaches can also be combined. The recent applications of fusion-protein technology in protein crystallization from the work of our own and other laboratories are briefly reviewed.

  10. INTRODUCTION: Status report on fusion research

    NASA Astrophysics Data System (ADS)

    Burkart, Werner

    2005-10-01

    A major milestone on the path to fusion energy was reached in June 2005 on the occasion of the signing of the joint declaration of all parties to the ITER negotiations, agreeing on future arrangements and on the construction site at Cadarache in France. The International Atomic Energy Agency has been promoting fusion activities since the late 1950s; it took over the auspices of the ITER Conceptual Design Activities in 1988, and of the ITER Engineering and Design Activities in 1992. The Agency continues its support to Member States through the organization of consultancies, workshops and technical meetings, the most prominent being the series of International Fusion Energy Conferences (formerly called the International Conference on Plasma Physics and Controlled Nuclear Fusion Research). The meetings serve as a platform for experts from all Member States to have open discussions on their latest accomplishments as well as on their problems and eventual solutions. The papers presented at the meetings and conferences are routinely published, many being sent to the journal it Nuclear Fusion, co-published monthly by Institute of Physics Publishing, Bristol, UK. The journal's reputation is reflected in the fact that it is a world-renowned publication, and the International Fusion Research Council has used it for the publication of a Status Report on Controlled Thermonuclear Fusion in 1978 and 1990. This present report marks the conclusion of the preparatory phases of ITER activities. It provides background information on the progress of fusion research within the last 15 years. The International Fusion Research Council (IFRC), which initiated the report, was fully aware of the complexities of including all scientific results in just one paper, and so decided to provide an overview and extensive references for the interested reader who need not necessarily be a fusion specialist. Professor Predhiman K. Kaw, Chairman, prepared the report on behalf of the IFRC, reflecting

  11. A reliability-based track fusion algorithm.

    PubMed

    Xu, Li; Pan, Liqiang; Jin, Shuilin; Liu, Haibo; Yin, Guisheng

    2015-01-01

    The common track fusion algorithms in multi-sensor systems have some defects, such as serious imbalances between accuracy and computational cost, the same treatment of all the sensor information regardless of their quality, high fusion errors at inflection points. To address these defects, a track fusion algorithm based on the reliability (TFR) is presented in multi-sensor and multi-target environments. To improve the information quality, outliers in the local tracks are eliminated at first. Then the reliability of local tracks is calculated, and the local tracks with high reliability are chosen for the state estimation fusion. In contrast to the existing methods, TFR reduces high fusion errors at the inflection points of system tracks, and obtains a high accuracy with less computational cost. Simulation results verify the effectiveness and the superiority of the algorithm in dense sensor environments.

  12. Mirror Fusion Test Facility magnet system

    SciTech Connect

    VanSant, J.H.; Kozman, T.A.; Bulmer, R.H.; Ng, D.S.

    1981-09-11

    In 1979, R.H. Bulmer of Lawrence Livermore National Laboratory (LLNL) discussed a proposed tandem-mirror magnet system for the Mirror Fusion Test Facility (MFTF) at the 8th symposium on Engineering Problems in Fusion Research. Since then, Congress has voted funds for expanding LLNL's MFTF to a tandem-mirror facility (designated MFTF-B). The new facility, scheduled for completion by 1985, will seek to achieve two goals: (1) Energy break-even capability (Q or the ratio of fusion energy to plasma heating energy = 1) of mirror fusion, (2) Engineering feasibility of reactor-scale machines. Briefly stated, 22 superconducting magnets contained in a 11-m-diam by 65-m-long vacuum vessel will confine a fusion plasma fueled by 80 axial streaming-plasma guns and over 40 radial neutral beams. We have already completed a preliminary design of this magnet system.

  13. Economic potential of magnetic fusion energy

    SciTech Connect

    Henning, C.D.

    1981-03-10

    Scientific feasibility of magnetic fusion is no longer seriously in doubt. Rapid advances have been made in both tokamak and mirror research, leading to a demonstration in the TFTR tokamak at Princeton in 1982 and the tandem mirror MFTF-B at Livermore in 1985. Accordingly, the basis is established for an aggressive engineering thrust to develop a reactor within this century. However, care must be taken to guide the fusion program towards an economically and environmentally viable goal. While the fusion fuels are essentially free, capital costs of reactors appear to be at least as large as current power plants. Accordingly, the price of electricity will not decline, and capital availability for reactor constructions will be important. Details of reactor cost projections are discussed and mechanisms suggested for fusion power implementation. Also discussed are some environmental and safety aspects of magnetic fusion.

  14. Public Relations on Fusion in Europe

    NASA Astrophysics Data System (ADS)

    Ongena, J.; van Oost, G.; Paris, P. J.

    2000-10-01

    A summary will be presented of PR efforts on fusion energy research in Europe. A 3-D movie of a fusion research experimental reactor has been realized at the start of this year. It has been made entirely on virtual animation basis. Two versions exists, a short version of 3 min., as a video clip, and a longer version of nearly 8 min. Both could be viewed in 3D, using special projections and passive glasses or in normal VHS video projections. A new CD-ROM for individual and classroom use will be presented, discussing (i) the different energy forms, (ii) general principles of fusion, (iii) current research efforts and (iv) future prospects of fusion. This CD-ROM is now produced in English, German, French, Spanish, Italian and Portuguese Several new brochures and leaflets intended to increase the public awareness on fusion in Europe will be on display.

  15. Mirror Advanced Reactor Study (MARS). Final report. Volume 1-B. Commercial fusion electric plant

    SciTech Connect

    Donohue, M.L.; Price, M.E.

    1984-07-01

    Volume 1-B contains the following chapters: (1) blanket and reflector; (2) central cell shield; (3) central cell structure; (4) heat transport and energy conversion; (5) tritium systems; (6) cryogenics; (7) maintenance; (8) safety; (9) radioactivity, activation, and waste disposal; (10) instrumentation and control; (11) balance of plant; (12) plant startup and operation; (13) plant availability; (14) plant construction; and (15) economic analysis.

  16. Mirror Advanced Reactor Study (MARS). Final report. Volume 2. Commercial fusion synfuels plant

    SciTech Connect

    Donohue, M.L.; Price, M.E.

    1984-07-01

    Volume 2 contains the following chapters: (1) synfuels; (2) physics base and parameters for TMR; (3) high-temperature two-temperature-zone blanket system for synfuel application; (4) thermochemical hydrogen processes; (5) interfacing the sulfur-iodine cycle; (6) interfacing the reactor with the thermochemical process; (7) tritium control in the blanket system; (8) the sulfur trioxide fluidized-bed composer; (9) preliminary cost estimates; and (10) fuels beyond hydrogen. (MOW)

  17. Magneized target fusion: An overview of the concept

    SciTech Connect

    Kirkpatrick, R.C.

    1994-12-31

    Magnetized target fusion (MTF) seeks to take advantage of the reduction of thermal conductivity through the application of a strong magneticfield and thereby ease the requirements for reaching fusion conditions in a thermonuclear (TN) fusion fuel. A potentially important benefit of the strong field in the partial trapping of energetic charged particles to enhance energy deposition by the TN fusion reaction products. The essential physics is described. MTF appears to lead to fusion targets that require orders of magnitude less power and intensity for fusion ignition than currently proposed (unmagnetized) inertial confinement fusion (ICF) targets do, making some very energetic pulsed power drivers attractive for realizing controlled fusion.

  18. Remote Sensing Image Fusion Using Ica and Optimized Wavelet Transform

    NASA Astrophysics Data System (ADS)

    Hnatushenko, V. V.; Vasyliev, V. V.

    2016-06-01

    In remote-sensing image processing, fusion (pan-sharpening) is a process of merging high-resolution panchromatic and lower resolution multispectral (MS) imagery to create a single high-resolution color image. Many methods exist to produce data fusion results with the best possible spatial and spectral characteristics, and a number have been commercially implemented. However, the pan-sharpening image produced by these methods gets the high color distortion of spectral information. In this paper, to minimize the spectral distortion we propose a remote sensing image fusion method which combines the Independent Component Analysis (ICA) and optimization wavelet transform. The proposed method is based on selection of multiscale components obtained after the ICA of images on the base of their wavelet decomposition and formation of linear forms detailing coefficients of the wavelet decomposition of images brightness distributions by spectral channels with iteratively adjusted weights. These coefficients are determined as a result of solving an optimization problem for the criterion of maximization of information entropy of the synthesized images formed by means of wavelet reconstruction. Further, reconstruction of the images of spectral channels is done by the reverse wavelet transform and formation of the resulting image by superposition of the obtained images. To verify the validity, the new proposed method is compared with several techniques using WorldView-2 satellite data in subjective and objective aspects. In experiments we demonstrated that our scheme provides good spectral quality and efficiency. Spectral and spatial quality metrics in terms of RASE, RMSE, CC, ERGAS and SSIM are used in our experiments. These synthesized MS images differ by showing a better contrast and clarity on the boundaries of the "object of interest - the background". The results show that the proposed approach performs better than some compared methods according to the performance metrics.

  19. Commercial SNF Accident Release Fractions

    SciTech Connect

    J. Schulz

    2004-11-05

    The purpose of this analysis is to specify and document the total and respirable fractions for radioactive materials that could be potentially released from an accident at the repository involving commercial spent nuclear fuel (SNF) in a dry environment. The total and respirable release fractions are used to support the preclosure licensing basis for the repository. The total release fraction is defined as the fraction of total commercial SNF assembly inventory, typically expressed as an activity inventory (e.g., curies), of a given radionuclide that is released to the environment from a waste form. Radionuclides are released from the inside of breached fuel rods (or pins) and from the detachment of radioactive material (crud) from the outside surfaces of fuel rods and other components of fuel assemblies. The total release fraction accounts for several mechanisms that tend to retain, retard, or diminish the amount of radionuclides that are available for transport to dose receptors or otherwise can be shown to reduce exposure of receptors to radiological releases. The total release fraction includes a fraction of airborne material that is respirable and could result in inhalation doses; this subset of the total release fraction is referred to as the respirable release fraction. Accidents may involve waste forms characterized as: (1) bare unconfined intact fuel assemblies, (2) confined intact fuel assemblies, or (3) canistered failed commercial SNF. Confined intact commercial SNF assemblies at the repository are contained in shipping casks, canisters, or waste packages. Four categories of failed commercial SNF are identified: (1) mechanically and cladding-penetration damaged commercial SNF, (2) consolidated/reconstituted assemblies, (3) fuel rods, pieces, and debris, and (4) nonfuel components. It is assumed that failed commercial SNF is placed into waste packages with a mesh screen at each end (CRWMS M&O 1999). In contrast to bare unconfined fuel assemblies, the

  20. Passive-sensor data fusion

    NASA Astrophysics Data System (ADS)

    Kolitz, Stephan E.

    1991-08-01

    Problems in multi-sensor data fusion are addressed for passive (angle-only) sensors; the example used is a constellation of IR sensors on satellites in low-earth orbit, viewing up to several hundred ballistic missile targets. The sensor data used in the methodology of the report is 'post-detection,' with targets resolved on single pixels (it is possible for several targets to be resolved on the same pixel). A 'scan' by a sensor is modeled by the formation of a rectangular focal plane image of lit pixels (bits with value 1), representing the presence of at least one target, and unlit pixels (bits with value 0), representing the absence of a target, at a particular time. Approaches and algorithmic solutions are developed which address the following passive sensor data fusion problems: scan-to-scan target association, and association classification. The ultimate objective is to estimate target states, for use in a larger battle management system. Results indicate that successful scan-to-scan target association is feasible at scan rates >=2 Hz, independent of resolution. Sensor-to-sensor target association is difficult at low resolution; even with high-resolution sensors the performance of a standard two-sensor single scan approach is variable and unpredictable, since it is a function of the relative geometry of sensors and targets. A single-scan approach using the Varad algorithm and three sensors is not as sensitive to this relative geometry, but is usable only for high-resolution sensors. Innovative multi-scan and multi-sensor modifications of the three- sensor Varad algorithm are developed which provide excellent performance for a wide range of sensor resolutions. The multi-sensor multi-scan methodology also provides accurate information on the classification of target associations as correct or incorrect. For the scenarios examined with resolution cell sizes ranging from 300 m to 2 km, association errors are less than 5% and essentially no classification errors

  1. Noise suppressed, multifocus image fusion for enhanced intraoperative navigation.

    PubMed

    Feruglio, Paolo Fumene; Vinegoni, Claudio; Fexon, Lioubov; Thurber, Greg; Sbarbati, Andrea; Weissleder, Ralph

    2013-04-01

    Current intraoperative imaging systems are typically not able to provide 'sharp' images over entire large areas or entire organs. Distinct structures such as tissue margins or groups of malignant cells are therefore often difficult to detect, especially under low signal-to-noise-ratio conditions. In this report, we introduce a noise suppressed multifocus image fusion algorithm, that provides detailed reconstructions even when images are acquired under sub-optimal conditions, such is the case for real time fluorescence intraoperative surgery. The algorithm makes use of the Anscombe transform combined with a multi-level stationary wavelet transform with individual threshold-based shrinkage. While the imaging system is integrated with a respiratory monitor triggering system, it can be easily adapted to any commercial imaging system. The developed algorithm is made available as a plugin for Osirix. PMID:22887724

  2. Noise suppressed, multifocus image fusion for enhanced intraoperative navigation.

    PubMed

    Feruglio, Paolo Fumene; Vinegoni, Claudio; Fexon, Lioubov; Thurber, Greg; Sbarbati, Andrea; Weissleder, Ralph

    2013-04-01

    Current intraoperative imaging systems are typically not able to provide 'sharp' images over entire large areas or entire organs. Distinct structures such as tissue margins or groups of malignant cells are therefore often difficult to detect, especially under low signal-to-noise-ratio conditions. In this report, we introduce a noise suppressed multifocus image fusion algorithm, that provides detailed reconstructions even when images are acquired under sub-optimal conditions, such is the case for real time fluorescence intraoperative surgery. The algorithm makes use of the Anscombe transform combined with a multi-level stationary wavelet transform with individual threshold-based shrinkage. While the imaging system is integrated with a respiratory monitor triggering system, it can be easily adapted to any commercial imaging system. The developed algorithm is made available as a plugin for Osirix.

  3. Recombinational Cloning Using Gateway and In-Fusion Cloning Schemes

    PubMed Central

    Throop, Andrea L.; LaBaer, Joshua

    2015-01-01

    The comprehensive study of protein structure and function, or proteomics, depends on the obtainability of full-length cDNAs in species-specific expression vectors and subsequent functional analysis of the expressed protein. Recombinational cloning is a universal cloning technique based on site-specific recombination that is independent of the insert DNA sequence of interest, which differentiates this method from the classical restriction enzyme-based cloning methods. Recombinational cloning enables rapid and efficient parallel transfer of DNA inserts into multiple expression systems. This unit summarizes strategies for generating expression-ready clones using the most popular recombinational cloning technologies, including the commercially available Gateway® (Life Technologies) and In-Fusion® (Clontech) cloning technologies. PMID:25827088

  4. Overview of the LIBRA light ion beam fusion conceptual design

    SciTech Connect

    Moses, G.A.; Kulcinski, G.L.; Bruggink, D.; Engelstad, R.; Lovell, E.; MacFarlane, J.; Musicki, Z.; Peterson, R.; Sawan, M.; Sviatoslavsky, I.

    1989-03-01

    The LIBRA light ion beam fusion commercial reactor study is a self-consistent conceptual design of a 330 MWe power plant with an accompanying economic analysis. Fusion targets are imploded by 4 MJ shaped pulses of 30 MeV Li ions at a rate of 3 Hz. The target gain is 80, leading to a yield of 320 MJ. The high intensity part of the ion plate is delivered by 16 diodes through 16 separate z-pinch plasma channels formed in 100 torr of helium with trace amounts of lithium. The blanket is an array of porous flexible silicon carbide tubes with Li/sub 17/Pb/sub 83/ flowing downward through them. These tubes (INPORT units) shield the target chamber wall from both neutron damage and the shock overpressure of the target explosion. The target chamber is self-pumped by the target explosion generated overpressure into a surge tank partially filled with Li/sub 17/Pb/sub 83/ that surrounds the target chamber. This scheme refreshes the chamber at the desired 3 Hz frequency without excessive pumping demands. The blanket multiplication is 1.2 and the tritium breeding ratio is 1.4. The direct capital cost of LIBRA is estimated to be $2200/kWe.

  5. Noise suppressed, multifocus image fusion for enhanced intraoperative navigation

    PubMed Central

    Feruglio, Paolo Fumene; Vinegoni, Claudio; Fexon, Lyuba; Thurber, Greg; Sbarbati, Andrea; Weissleder, Ralph

    2013-01-01

    Current intraoperative imaging systems are typically not able to provide ‘sharp’ images over entire large areas or entire organs. Distinct structures such as tissue margins or groups of malignant cells are therefore often difficult to detect, especially under low signal-to-noise-ratio conditions. In this report, we introduce a noise suppressed multifocus image fusion algorithm, that provides detailed reconstructions even when images are acquired under sub-optimal conditions, such is the case for real time fluorescence intraoperative surgery. The algorithm makes use of the Anscombe transform combined with a multi-level stationary wavelet transform with individual threshold-based shrinkage. While the imaging system is integrated with a respiratory monitor triggering system, it can be easily adapted to any commercial imaging system. The developed algorithm is made available as a plugin for Osirix. Intraoperative detection of small malignant fluorescent cells using the proposed noise suppressed multifocus image fusion system. Red/Yellow circles indicate small groups of malignant cells. PMID:22887724

  6. INTRODUCTION: Status report on fusion research

    NASA Astrophysics Data System (ADS)

    Burkart, Werner

    2005-10-01

    A major milestone on the path to fusion energy was reached in June 2005 on the occasion of the signing of the joint declaration of all parties to the ITER negotiations, agreeing on future arrangements and on the construction site at Cadarache in France. The International Atomic Energy Agency has been promoting fusion activities since the late 1950s; it took over the auspices of the ITER Conceptual Design Activities in 1988, and of the ITER Engineering and Design Activities in 1992. The Agency continues its support to Member States through the organization of consultancies, workshops and technical meetings, the most prominent being the series of International Fusion Energy Conferences (formerly called the International Conference on Plasma Physics and Controlled Nuclear Fusion Research). The meetings serve as a platform for experts from all Member States to have open discussions on their latest accomplishments as well as on their problems and eventual solutions. The papers presented at the meetings and conferences are routinely published, many being sent to the journal it Nuclear Fusion, co-published monthly by Institute of Physics Publishing, Bristol, UK. The journal's reputation is reflected in the fact that it is a world-renowned publication, and the International Fusion Research Council has used it for the publication of a Status Report on Controlled Thermonuclear Fusion in 1978 and 1990. This present report marks the conclusion of the preparatory phases of ITER activities. It provides background information on the progress of fusion research within the last 15 years. The International Fusion Research Council (IFRC), which initiated the report, was fully aware of the complexities of including all scientific results in just one paper, and so decided to provide an overview and extensive references for the interested reader who need not necessarily be a fusion specialist. Professor Predhiman K. Kaw, Chairman, prepared the report on behalf of the IFRC, reflecting

  7. Ion Rings for Magnetic Fusion

    SciTech Connect

    Greenly, John, B.

    2005-07-31

    This Final Technical Report presents the results of the program, Ion Rings for Magnetic Fusion, which was carried out under Department of Energy funding during the period August, 1993 to January, 2005. The central objective of the program was to study the properties of field-reversed configurations formed by ion rings. In order to reach this objective, our experimental program, called the Field-reversed Ion Ring Experiment, FIREX, undertook to develop an efficient, economical technology for the production of field-reversed ion rings. A field-reversed configuration (FRC) in which the azimuthal (field-reversing) current is carried by ions with gyro-radius comparable to the magnetic separatrix radius is called a field-reversed ion ring. A background plasma is required for charge neutralization of the ring, and this plasma will be confined within the ring's closed magnetic flux. Ion rings have long been of interest as the basis of compact magnetic fusion reactors, as the basis for a high-power accelerator for an inertial fusion driver, and for other applications of high power ion beams or plasmas of high energy density. Specifically, the FIREX program was intended to address the longstanding question of the contribution of large-orbit ions to the observed stability of experimental FRCs to the MHD tilt mode. Typical experimental FRCs with s {approx} 2-4, where s is the ratio of separatrix radius to ion gyro-radius, have been stable to tilting, but desired values for a fusion reactor, s > 20, should be unstable. The FIREX ring would consist of a plasma with large s for the background ions, but with s {approx} 1 for the ring ions. By varying the proportions of these two populations, the minimum proportion of large-orbit ions necessary for stability could be determined. The incorporation of large-orbit ions, perhaps by neutral-beam injection, into an FRC has been advanced for the purpose of stabilizing, heating, controlling angular momentum, and aiding the formation of a

  8. Magnetic systems for fusion devices

    SciTech Connect

    Henning, C.D.

    1985-02-01

    Mirror experiments have led the way in applying superconductivity to fusion research because of unique requirements for high and steady magnetic fields. The first significant applications were Baseball II at LLNL and IMP at ORNL. More recently, the MFTF-B yin-yang coil was successfully tested and the entire tandem configuration is nearing completion. Tokamak magnets have also enjoyed recent success with the large coil project tests at ORNL, preceded by single coil tests in Japan and Germany. In the USSR, the T-7 Tokamak has been operational for many years and the T-15 Tokamak is under construction, with the TF coils nearing completion. Also the Tore Supra is being built in France.

  9. Laser-driven fusion reactor

    DOEpatents

    Hedstrom, J.C.

    1973-10-01

    A laser-driven fusion reactor consisting of concentric spherical vessels in which the thermonuclear energy is derived from a deuterium-tritium (D + T) burn within a pellet'', located at the center of the vessels and initiated by a laser pulse. The resulting alpha -particle energy and a small fraction of the neutron energy are deposited within the pellet; this pellet energy is eventually transformed into sensible heat of lithium in a condenser outside the vessels. The remaining neutron energy is dissipated in a lithium blanket, located within the concentric vessels, where the fuel ingredient, tritium, is also produced. The heat content of the blanket and of the condenser lithium is eventually transferred to a conventional thermodynamic plant where the thermal energy is converted to electrical energy in a steam Rankine cycle. (Official Gazette)

  10. Status of cold fusion (2010).

    PubMed

    Storms, Edmund

    2010-10-01

    The phenomenon called cold fusion has been studied for the last 21 years since its discovery by Profs. Fleischmann and Pons in 1989. The discovery was met with considerable skepticism, but supporting evidence has accumulated, plausible theories have been suggested, and research is continuing in at least eight countries. This paper provides a brief overview of the major discoveries and some of the attempts at an explanation. The evidence supports the claim that a nuclear reaction between deuterons to produce helium can occur in special materials without application of high energy. This reaction is found to produce clean energy at potentially useful levels without the harmful byproducts normally associated with a nuclear process. Various requirements of a model are examined.

  11. Multishell inertial confinement fusion target

    DOEpatents

    Holland, James R.; Del Vecchio, Robert M.

    1984-01-01

    A method of fabricating multishell fuel targets for inertial confinement fusion usage. Sacrificial hemispherical molds encapsulate a concentric fuel pellet which is positioned by fiber nets stretched tautly across each hemispherical mold section. The fiber ends of the net protrude outwardly beyond the mold surfaces. The joint between the sacrificial hemispheres is smoothed. A ceramic or glass cover is then deposited about the finished mold surfaces to produce an inner spherical surface having continuously smooth surface configuration. The sacrificial mold is removed by gaseous reaction accomplished through the porous ceramic cover prior to enclosing of the outer sphere by addition of an outer coating. The multishell target comprises the inner fuel pellet concentrically arranged within a surrounding coated cover or shell by fiber nets imbedded within the cover material.

  12. Multishell inertial confinement fusion target

    DOEpatents

    Holland, James R.; Del Vecchio, Robert M.

    1987-01-01

    A method of fabricating multishell fuel targets for inertial confinement fusion usage. Sacrificial hemispherical molds encapsulate a concentric fuel pellet which is positioned by fiber nets stretched tautly across each hemispherical mold section. The fiber ends of the net protrude outwardly beyond the mold surfaces. The joint between the sacrificial hemispheres is smoothed. A ceramic or glass cover is then deposited about the finished mold surfaces to produce an inner spherical surface having continuously smooth surface configuration. The sacrificial mold is removed by gaseous reactions accomplished through the porous ceramic cover prior to enclosing of the outer sphere by addition of an outer coating. The multishell target comprises the inner fuel pellet concentrically arranged within a surrounding coated cover or shell by fiber nets imbedded within the cover material.

  13. Inertial-confinement-fusion targets

    SciTech Connect

    Hendricks, C.D.

    1982-08-10

    Much of the research in laser fusion has been done using simple ball on-stalk targets filled with a deuterium-tritium mixture. The targets operated in the exploding pusher mode in which the laser energy was delivered in a very short time (approx. 100 ps or less) and was absorbed by the glass wall of the target. The high energy density in the glass literally exploded the shell with the inward moving glass compressing the DT fuel to high temperatures and moderate densities. Temperatures achieved were high enough to produce DT reactions and accompanying thermonuclear neutrons and alpha particles. The primary criteria imposed on the target builders were: (1) wall thickness, (2) sphere diameter, and (3) fuel in the sphere.

  14. Status of cold fusion (2010)

    NASA Astrophysics Data System (ADS)

    Storms, Edmund

    2010-10-01

    The phenomenon called cold fusion has been studied for the last 21 years since its discovery by Profs. Fleischmann and Pons in 1989. The discovery was met with considerable skepticism, but supporting evidence has accumulated, plausible theories have been suggested, and research is continuing in at least eight countries. This paper provides a brief overview of the major discoveries and some of the attempts at an explanation. The evidence supports the claim that a nuclear reaction between deuterons to produce helium can occur in special materials without application of high energy. This reaction is found to produce clean energy at potentially useful levels without the harmful byproducts normally associated with a nuclear process. Various requirements of a model are examined.

  15. Progress in Heavy Ion Fusion

    SciTech Connect

    Herrmannsfeldt, W.B.

    1988-09-01

    The progress of the field of Heavy Ion Fusion has been documented in the proceedings of the series of International Symposia that, in recent years, have occurred every second year. The latest of these conferences was hosted by Gesellshaft fuer Schwerionenforshung (GSI) in Darmstadt, West Germany, June 28-30, 1988. For this report, a few highlights from the conference are selected, stressing experimental progress and prospects for future advances. A little extra time is devoted to report on the developments at the Lawrence Berkeley Laboratory (LBL) which is the center for most of the HIFAR program. The Director of the HIFAR program at LBL is Denis Keefe, who presented the HIF report at the last two of the meetings in this series, and in whose place the author is appearing now. 4 refs., 1 fig.

  16. Transitioning NASA Space Operations to Commercial Services

    NASA Technical Reports Server (NTRS)

    Gilbert, Charlene E.

    1998-01-01

    Major considerations associated with "Transitioning NASA Space Operations to Commercial Services" are presented in viewgraph form. Specific topics include: 1) Government use of commercial frequencies vs. commercial use of commercial frequencies for government use; 2) Commercial use of government frequencies; 3) Government vs commercial: Access techniques, data formats, and modulation and coding; 4) Government need for multiple sources: backup and competition; 5) Government in perceived competition with commercial service providers if TDRSS is used for commercial purposes; and 6) Coordination required among plans for CSOC, NSCP, and satellite industry.

  17. Commercial Crew Development Program Overview

    NASA Technical Reports Server (NTRS)

    Russell, Richard W.

    2011-01-01

    NASA's Commercial Crew Development Program is designed to stimulate efforts within the private sector that will aid in the development and demonstration of safe, reliable, and cost-effective space transportation capabilities. With the goal of delivery cargo and eventually crew to Low Earth Orbit (LEO) and the International Space Station (ISS) the program is designed to foster the development of new spacecraft and launch vehicles in the commercial sector. Through Space Act Agreements (SAAs) in 2011 NASA provided $50M of funding to four partners; Blue Origin, The Boeing Company, Sierra Nevada Corporation, and SpaceX. Additional, NASA has signed two unfunded SAAs with ATK and United Space Alliance. This paper will give a brief summary of these SAAs. Additionally, a brief overview will be provided of the released version of the Commercial Crew Development Program plans and requirements documents.

  18. SHP2 regulates osteoclastogenesis by promoting preosteoclast fusion

    PubMed Central

    Zhou, Yi; Mohan, Aron; Moore, Douglas C.; Lin, Liangjun; Zhou, Frank Li; Cao, Jay; Wu, Qian; Qin, Yi-Xian; Reginato, Anthony M.; Ehrlich, Michael G.; Yang, Wentian

    2015-01-01

    Genes that regulate osteoclast (OC) development and function in both physiologic and disease conditions remain incompletely understood. Shp2 (the Src homology-2 domain containing protein tyrosine phosphatase 2), a ubiquitously expressed cytoplasmic protein tyrosine phosphatase, is implicated in regulating M-CSF and receptor activator of nuclear factor-κB ligand (RANKL)–evoked signaling; its role in osteoclastogenesis and bone homeostasis, however, remains unknown. Using a tissue-specific gene knockout approach, we inactivated Shp2 expression in murine OCs. Shp2 mutant mice are phenotypically osteopetrotic, featuring a marked increase of bone volume (BV)/total volume (TV) (+42.8%), trabeculae number (Tb.N) (+84.1%), structure model index (+119%), and a decrease of trabecular thickness (Tb.Th) (−34.1%) and trabecular spacing (Tb.Sp) (−41.0%). Biochemical analyses demonstrate that Shp2 is required for RANKL-induced formation of giant multinucleated OCs by up-regulating the expression of nuclear factor of activated T cells, cytoplasmic 1 (Nfatc1), a master transcription factor that is indispensable for terminal OC differentiation. Shp2 deletion, however, has minimal effect on M-CSF–dependent survival and proliferation of OC precursors. Instead, its deficiency aborts the fusion of OC precursors and formation of multinucleated OCs and decreases bone matrix resorption. Moreover, pharmacological intervention of Shp2 is sufficient to prevent preosteoclast fusion in vitro. These findings uncover a novel mechanism through which Shp2 regulates osteoclastogenesis by promoting preosteoclast fusion. Shp2 or its signaling partners could potentially serve as pharmacological targets to regulate the population of OCs locally and/or systematically, and thus treat OC-related diseases, such as periprosthetic osteolysis and osteoporosis.—Zhou, Y., Mohan, A., Moore, D. C., Lin, L., Zhou, F. L., Cao, J., Wu, Q., Qin, Y.–X., Reginato, A. M., Ehrlich, M. G., Yang, W. SHP2

  19. Evaluation of commercial herbal shampoos.

    PubMed

    Mainkar, A R; Jolly, C I

    2000-10-01

    Selecting the evaluation parameters of a shampoo is a challenging task, simply because of the multitude of both subjective and instrumental test methodologies available for this purpose. The present paper focuses on the evaluation of herbal shampoos using some of these parameters. Commonly used test protocols for foam test, detergency, etc. are discussed. The commercial herbal shampoos are evaluated on the basis of these tests. The results of these tests also give an idea about what standards should be met by a shampoo formulated in the laboratory to be comparable with the commercial shampoos.

  20. Successful commercialization of nanophotonic technology

    NASA Astrophysics Data System (ADS)

    Jaiswal, Supriya L.; Clarke, Roger B. M.; Hyde, Sam C. W.

    2006-08-01

    The exploitation of nanotechnology from proof of principle to realizable commercial applications encounters considerable challenges in regards to high volume, large scale, low cost manufacturability and social ethics. This has led to concerns over converting powerful intellectual property into realizable, industry attractive technologies. At The Technology Partnership we specifically address the issue of successful integration of nanophotonics into industry in markets such as biomedical, ophthalmic, energy, telecommunications, and packaging. In this paper we draw on a few examples where we have either developed industrial scale nanophotonic technology or engineering platforms which may be used to fortify nano/microphotonic technologies and enhance their commercial viability.

  1. Flat conductor cable commercialization project

    NASA Technical Reports Server (NTRS)

    Hogarth, P.; Wadsworth, E.

    1977-01-01

    An undercarpet flat conductor cable and a baseboard flat conductor cable system were studied for commercialization. The undercarpet system is designed for use in office and commercial buildings. It employs a flat power cable, protected by a grounded metal shield, that terminates in receptacles mounted on the floor. It is designed to interface with a flat conductor cable telephone system. The baseboard system consists of a flat power cable mounted in a plastic raceway; both the raceway and the receptacles are mounted on the surface of the baseboard. It is designed primarily for use in residential buildings, particularly for renovation and concrete and masonry construction.

  2. Differential cholesterol binding by class II fusion proteins determines membrane fusion properties.

    PubMed

    Umashankar, M; Sánchez-San Martín, Claudia; Liao, Maofu; Reilly, Brigid; Guo, Alice; Taylor, Gwen; Kielian, Margaret

    2008-09-01

    The class II fusion proteins of the alphaviruses and flaviviruses mediate virus infection by driving the fusion of the virus membrane with that of the cell. These fusion proteins are triggered by low pH, and their structures are strikingly similar in both the prefusion dimer and the postfusion homotrimer conformations. Here we have compared cholesterol interactions during membrane fusion by these two groups of viruses. Using cholesterol-depleted insect cells, we showed that fusion and infection by the alphaviruses Semliki Forest virus (SFV) and Sindbis virus were strongly promoted by cholesterol, with similar sterol dependence in laboratory and field isolates and in viruses passaged in tissue culture. The E1 fusion protein from SFV bound cholesterol, as detected by labeling with photocholesterol and by cholesterol extraction studies. In contrast, fusion and infection by numerous strains of the flavivirus dengue virus (DV) and by yellow fever virus 17D were cholesterol independent, and the DV fusion protein did not show significant cholesterol binding. SFV E1 is the first virus fusion protein demonstrated to directly bind cholesterol. Taken together, our results reveal important functional differences conferred by the cholesterol-binding properties of class II fusion proteins.

  3. In vitro fusion of Acanthamoeba phagolysosomes. I. Demonstration and quantitation of vacuole fusion in Acanthamoeba homogenates.

    PubMed

    Oates, P J; Touster, O

    1976-02-01

    Fusion of phagolysosomes (PLs) has been demonstrated to occur in vitro. Two separate cell homogenates of the ameba Acanthamoeba sp. (Neff) were prepared, each rich in PLs labeled with distinctive particulate markers. Portions of each were incubated together in vitro and fusion occurred as evidenced by the appearance of PLs containing both types of markers. Fusion was confirmed by electron microscopy, including serial sectioning. The membranes of fused vacuoles excluded the dye eosin Y. Surviving cells in the homogenates were not responsible for the observed fusion. Fusion was obtained using either synthetic markers (polystyrene and polyvinyltoluene latex) or biological markers (autoclaved yeast cells and glutaraldehyde-fixed goat red blood cells), or a combination of both. The specificity of PL fusion in vivo appeared to be maintained in vitro. As determined by light and electron microscopy, the fusion reaction was dependent on time and temperature, and on the initial presence of membrane around both marker particles. A minimum of 10% of the vacuoles fused by 10 min of incubation at 30 degrees C, and no rupture of the vacuoles was detected during this time. After 10 min of incubation, vacuole rupture began and fusion ceased. At a constant initial vacuole concentration, the extent of PL fusion in vitro was quantitatively reproducible. This appears to be a promising system for further investigation of membrane fusion in the lysosomal system. PMID:1245550

  4. Statistical label fusion with hierarchical performance models

    PubMed Central

    Asman, Andrew J.; Dagley, Alexander S.; Landman, Bennett A.

    2014-01-01

    Label fusion is a critical step in many image segmentation frameworks (e.g., multi-atlas segmentation) as it provides a mechanism for generalizing a collection of labeled examples into a single estimate of the underlying segmentation. In the multi-label case, typical label fusion algorithms treat all labels equally – fully neglecting the known, yet complex, anatomical relationships exhibited in the data. To address this problem, we propose a generalized statistical fusion framework using hierarchical models of rater performance. Building on the seminal work in statistical fusion, we reformulate the traditional rater performance model from a multi-tiered hierarchical perspective. This new approach provides a natural framework for leveraging known anatomical relationships and accurately modeling the types of errors that raters (or atlases) make within a hierarchically consistent formulation. Herein, we describe several contributions. First, we derive a theoretical advancement to the statistical fusion framework that enables the simultaneous estimation of multiple (hierarchical) performance models within the statistical fusion context. Second, we demonstrate that the proposed hierarchical formulation is highly amenable to the state-of-the-art advancements that have been made to the statistical fusion framework. Lastly, in an empirical whole-brain segmentation task we demonstrate substantial qualitative and significant quantitative improvement in overall segmentation accuracy. PMID:24817809

  5. Multisensor image fusion guidelines in remote sensing

    NASA Astrophysics Data System (ADS)

    Pohl, C.

    2016-04-01

    Remote sensing delivers multimodal and -temporal data from the Earth's surface. In order to cope with these multidimensional data sources and to make the most of them, image fusion is a valuable tool. It has developed over the past few decades into a usable image processing technique for extracting information of higher quality and reliability. As more sensors and advanced image fusion techniques have become available, researchers have conducted a vast amount of successful studies using image fusion. However, the definition of an appropriate workflow prior to processing the imagery requires knowledge in all related fields - i.e. remote sensing, image fusion and the desired image exploitation processing. From the findings of this research it can be seen that the choice of the appropriate technique, as well as the fine-tuning of the individual parameters of this technique, is crucial. There is still a lack of strategic guidelines due to the complexity and variability of data selection, processing techniques and applications. This paper gives an overview on the state-of-the-art in remote sensing image fusion including sensors and applications. Putting research results in image fusion from the past 15 years into a context provides a new view on the subject and helps other researchers to build their innovation on these findings. Recommendations of experts help to understand further needs to achieve feasible strategies in remote sensing image fusion.

  6. Establishment of an Institute for Fusion Studies

    NASA Astrophysics Data System (ADS)

    Hazeltine, R. D.

    1992-07-01

    The Institute for Fusion Studies is a national center for theoretical fusion plasma physics research. Its purposes are: (1) to conduct research on theoretical questions concerning the achievement of controlled fusion energy by means of magnetic confinement--including both fundamental problems of long-range significance, as well as shorter-term issues; (2) to serve as a center for information exchange, nationally and internationally, by hosting exchange visits, conferences, and workshops; (3) and to train students and postdoctoral research personnel for the fusion energy program and plasma physics research areas. The theoretical research results that are obtained by the Institute contribute mainly to the progress of national and international efforts in nuclear fusion research, whose goal is the development of fusion power as a basic energy source. In addition to its primary focus on fusion physics, the Institute is also involved with research in related fields, such as advanced computing techniques, nonlinear dynamics, plasma astrophysics, and accelerator physics. The work of EFS scientists continued to receive national and international recognition. Numerous invited papers were given during the past year at workshops, conferences, and scientific meetings. Last year IFS scientists published 95 scientific articles in technical journals and monographs.

  7. Fusion pore regulation of transmitter release.

    PubMed

    Fernández-Peruchena, Carlos; Navas, Sergio; Montes, María A; Alvarez de Toledo, Guillermo

    2005-09-01

    During the last decade a wealth of new information about the properties of the exocytotic fusion pore is changing our current view of exocytosis. The exocytotic fusion pore, a necessary stage before the full merging of the vesicle membrane with the plasma membrane, is becoming a key cellular structure that might critically control the amount of neurotransmitter released into the synaptic cleft and that can be subjected to control by second messengers and phosphorylated proteins. Fusion pores form, expand to fully merge membranes, or can close leaving an intact and identical synaptic vesicle in place for a new round of exocytosis. Transient formation of fusion pores is the mechanistic representation of the "kiss-and-run" hypothesis of transmitter release and offers new alternatives for synaptic vesicle recycling besides to the classical mechanism mediated by clathrin coat endocytosis. For vesicle recycling transient fusion pores ensures a fast mechanism for maintaining an active pool of synaptic vesicles. The size reached by transient fusion pores and the time spent on the open state can determine the release of subquantal synaptic transmission, which could be a mechanism of synaptic potentiation. In this review we will described the electrophysiological and fluorescence methods that contribute to further explore the biophysical properties of the exocytotic fusion pore and the relevant experiments obtained by these methods.

  8. Status and problems of fusion reactor development.

    PubMed

    Schumacher, U

    2001-03-01

    Thermonuclear fusion of deuterium and tritium constitutes an enormous potential for a safe, environmentally compatible and sustainable energy supply. The fuel source is practically inexhaustible. Further, the safety prospects of a fusion reactor are quite favourable due to the inherently self-limiting fusion process, the limited radiologic toxicity and the passive cooling property. Among a small number of approaches, the concept of toroidal magnetic confinement of fusion plasmas has achieved most impressive scientific and technical progress towards energy release by thermonuclear burn of deuterium-tritium fuels. The status of thermonuclear fusion research activity world-wide is reviewed and present solutions to the complicated physical and technological problems are presented. These problems comprise plasma heating, confinement and exhaust of energy and particles, plasma stability, alpha particle heating, fusion reactor materials, reactor safety and environmental compatibility. The results and the high scientific level of this international research activity provide a sound basis for the realisation of the International Thermonuclear Experimental Reactor (ITER), whose goal is to demonstrate the scientific and technological feasibility of a fusion energy source for peaceful purposes.

  9. Establishment of an Institute for Fusion Studies

    SciTech Connect

    Hazeltine, R.D.

    1992-07-01

    The Institute for Fusion Studies is a national center for theoretical fusion plasma physics research. Its purposes are: (1) to conduct research on theoretical questions concerning the achievement of controlled fusion energy by means of magnetic confinement--including both fundamental problems of long-range significance, as well as shorter-term issues; (2) to serve as a center for information exchange, nationally and internationally, by hosting exchange visits, conferences, and workshops; (3) and to train students and postdoctoral research personnel for the fusion energy program and plasma physics research areas. The theoretical research results that are obtained by the Institute contribute mainly to the progress of national and international efforts in nuclear fusion research, whose goal is the development of fusion power.as a basic energy source. In addition to its primary focus on fusion physics, the Institute is also involved with research in related fields, such as advanced computing techniques, nonlinear dynamics, plasma astrophysics, and accelerator physics. The work of EFS scientists continued to receive national and international recognition. Numerous invited papers were given during the past year at workshops, conferences, and scientific meetings. Last year IFS scientists published 95 scientific articles in technical journals and monographs.

  10. Engineering Challenges in Antiproton Triggered Fusion Propulsion

    SciTech Connect

    Cassenti, Brice; Kammash, Terry

    2008-01-21

    During the last decade antiproton triggered fusion propulsion has been investigated as a method for achieving high specific impulse, high thrust in a nuclear pulse propulsion system. In general the antiprotons are injected into a pellet containing fusion fuel with a small amount of fissionable material (i.e., an amount less than the critical mass) where the products from the fission are then used to trigger a fusion reaction. Initial calculations and simulations indicate that if magnetically insulated inertial confinement fusion is used that the pellets should result in a specific impulse of between 100,000 and 300,000 seconds at high thrust. The engineering challenges associated with this propulsion system are significant. For example, the antiprotons must be precisely focused. The pellet must be designed to contain the fission and initial fusion products and this will require strong magnetic fields. The fusion fuel must be contained for a sufficiently long time to effectively release the fusion energy, and the payload must be shielded from the radiation, especially the excess neutrons emitted, in addition to many other particles. We will review the recent progress, possible engineering solutions and the potential performance of these systems.

  11. Summary of the International Workshop on Magnetic Fusion Energy (MFE) Roadmapping in the ITER Era; 7-10 September 2011, Princeton, NJ, USA

    NASA Astrophysics Data System (ADS)

    Neilson, G. H.; Federici, G.; Li, J.; Maisonnier, D.; Wolf, R.

    2012-04-01

    With the ITER project now well under way, the countries engaged in fusion research are planning, with renewed intensity, the research and major facilities needed to develop the science and technology for harnessing fusion energy. The Workshop on MFE Roadmapping in the ITER Era was organized to provide a timely forum for an international exchange of technical information and strategic perspectives on how best to tackle the remaining challenges leading to a magnetic fusion DEMO, a nuclear fusion device or devices with a level of physics and technology integration necessary to cover the essential elements of a commercial fusion power plant. Presentations addressed issues under four topics: (1) Perspectives on DEMO and the roadmap to DEMO; (2) Technology; (3) Physics-Technology integration and optimization; and (4) Major facilities on the path to DEMO. Participants identified a set of technical issues of high strategic importance, where the development strategy strongly influences the overall roadmap, and where there are divergent understandings in the world community, namely (1) the assumptions used in fusion design codes, (2) the strategy for fusion materials development, (3) the strategy for blanket development, (4) the strategy for plasma exhaust solution development and (5) the requirements and state of readiness for next-step facility options. It was concluded that there is a need to continue and to focus the international discussion concerning the scientific and technical issues that determine the fusion roadmap, and it was suggested that an international activity be organized under appropriate auspices to foster international cooperation on these issues.

  12. Visualize Your Data with Google Fusion Tables

    NASA Astrophysics Data System (ADS)

    Brisbin, K. E.

    2011-12-01

    Google Fusion Tables is a modern data management platform that makes it easy to host, manage, collaborate on, visualize, and publish tabular data online. Fusion Tables allows users to upload their own data to the Google cloud, which they can then use to create compelling and interactive visualizations with the data. Users can view data on a Google Map, plot data in a line chart, or display data along a timeline. Users can share these visualizations with others to explore and discover interesting trends about various types of data, including scientific data such as invasive species or global trends in disease. Fusion Tables has been used by many organizations to visualize a variety of scientific data. One example is the California Redistricting Map created by the LA Times: http://goo.gl/gwZt5 The Pacific Institute and Circle of Blue have used Fusion Tables to map the quality of water around the world: http://goo.gl/T4SX8 The World Resources Institute mapped the threat level of coral reefs using Fusion Tables: http://goo.gl/cdqe8 What attendees will learn in this session: This session will cover all the steps necessary to use Fusion Tables to create a variety of interactive visualizations. Attendees will begin by learning about the various options for uploading data into Fusion Tables, including Shapefile, KML file, and CSV file import. Attendees will then learn how to use Fusion Tables to manage their data by merging it with other data and controlling the permissions of the data. Finally, the session will cover how to create a customized visualization from the data, and share that visualization with others using both Fusion Tables and the Google Maps API.

  13. Dynamical effects in fusion with exotic nuclei

    NASA Astrophysics Data System (ADS)

    Vo-Phuoc, K.; Simenel, C.; Simpson, E. C.

    2016-08-01

    Background: Reactions with stable beams have demonstrated strong interplay between nuclear structure and fusion. Exotic beam facilities open new perspectives to understand the impact of neutron skin, large isospin, and weak binding energies on fusion. Microscopic theories of fusion are required to guide future experiments. Purpose: To investigate new effects of exotic structures and dynamics in near-barrier fusion with exotic nuclei. Method: Microscopic approaches based on the Hartree-Fock (HF) mean-field theory are used for studying fusion barriers in -54Ca40+116Sn reactions for even isotopes. Bare potential barriers are obtained assuming frozen HF ground-state densities. Dynamical effects on the barrier are accounted for in time-dependent Hartree-Fock (TDHF) calculations of the collisions. Vibrational couplings are studied in the coupled-channel framework and near-barrier nucleon transfer is investigated with TDHF calculations. Results: The development of a neutron skin in exotic calcium isotopes strongly lowers the bare potential barrier. However, this static effect is not apparent when dynamical effects are included. On the contrary, a fusion hindrance is observed in TDHF calculations with the most neutron-rich calcium isotopes which cannot be explained by vibrational couplings. Transfer reactions are also important in these systems due to charge equilibration processes. Conclusions: Despite its impact on the bare potential, the neutron skin is not seen as playing an important role in the fusion dynamics. However, the charge transfer with exotic projectiles could lead to an increase of the Coulomb repulsion between the fragments, suppressing fusion. The effects of transfer and dissipative mechanisms on fusion with exotic nuclei deserve further studies.

  14. Real-time fusion of low-light CCD and uncooled IR imagery for color night vision

    NASA Astrophysics Data System (ADS)

    Aguilar, Mario; Fay, David A.; Ross, W. D.; Waxman, Allen M.; Ireland, David B.; Racamato, Joseph P.

    1998-07-01

    We present an approach to color night vision through fusion of information derived from visible and thermal infrared sensors. Building on the work reported at SPIE in 1996 and 1997, we show how opponent-color processing and center-surround shunting neural networks can achieve informative multi-band image fusion. In particular, by emulating spatial and color processing in the retina, we demonstrate an effective strategy for multi-sensor color-night vision. We have developed a real- time visible/IR fusion processor from multiple C80 DSP chips using commercially available Matrox Genesis boards, which we use in conjunction with the Lincoln Lab low-light CCD and a Raytheon TI Systems uncooled IR camera. Limited human factors testing of visible/IR fusion is presented showing improvements in human performance using our color fused imagery relative to alternative fusion strategies or either single image modality alone. We conclude that fusion architectures that match opponent-sensor contrast to human opponent-color processing will yield fused image products of high image quality and utility.

  15. A NATIONAL COLLABORATORY TO ADVANCE THE SCIENCE OF HIGH TEMPERATURE PLASMA PHYSICS FOR MAGNETIC FUSION

    SciTech Connect

    Allen R. Sanderson; Christopher R. Johnson

    2006-08-01

    This report summarizes the work of the University of Utah, which was a member of the National Fusion Collaboratory (NFC) Project funded by the United States Department of Energy (DOE) under the Scientific Discovery through Advanced Computing Program (SciDAC) to develop a persistent infrastructure to enable scientific collaboration for magnetic fusion research. A five year project that was initiated in 2001, it the NFC built on the past collaborative work performed within the U.S. fusion community and added the component of computer science research done with the USDOE Office of Science, Office of Advanced Scientific Computer Research. The project was itself a collaboration, itself uniting fusion scientists from General Atomics, MIT, and PPPL and computer scientists from ANL, LBNL, and Princeton University, and the University of Utah to form a coordinated team. The group leveraged existing computer science technology where possible and extended or created new capabilities where required. The complete finial report is attached as an addendum. The In the collaboration, the primary technical responsibility of the University of Utah in the collaboration was to develop and deploy an advanced scientific visualization service. To achieve this goal, the SCIRun Problem Solving Environment (PSE) is used on FusionGrid for an advanced scientific visualization service. SCIRun is open source software that gives the user the ability to create complex 3D visualizations and 2D graphics. This capability allows for the exploration of complex simulation results and the comparison of simulation and experimental data. SCIRun on FusionGrid gives the scientist a no-license-cost visualization capability that rivals present day commercial visualization packages. To accelerate the usage of SCIRun within the fusion community, a stand-alone application built on top of SCIRun was developed and deployed. This application, FusionViewer, allows users who are unfamiliar with SCIRun to quickly create

  16. A recombinant fusion protein containing a spider toxin specific for the insect voltage-gated sodium ion channel shows oral toxicity towards insects of different orders.

    PubMed

    Yang, Sheng; Pyati, Prashant; Fitches, Elaine; Gatehouse, John A

    2014-04-01

    Recombinant fusion protein technology allows specific insecticidal protein and peptide toxins to display activity in orally-delivered biopesticides. The spider venom peptide δ-amaurobitoxin-PI1a, which targets insect voltage-gated sodium channels, was fused to the "carrier" snowdrop lectin (GNA) to confer oral toxicity. The toxin itself (PI1a) and an amaurobitoxin/GNA fusion protein (PI1a/GNA) were produced using the yeast Pichia pastoris as expression host. Although both proteins caused mortality when injected into cabbage moth (Mamestra brassicae) larvae, the PI1a/GNA fusion was approximately 6 times as effective as recombinant PI1a on a molar basis. PI1a alone was not orally active against cabbage moth larvae, but a single 30 μg dose of the PI1a/GNA fusion protein caused 100% larval mortality within 6 days when fed to 3rd instar larvae, and caused significant reductions in survival, growth and feeding in 4th - 6th instar larvae. Transport of fusion protein from gut contents to the haemolymph of cabbage moth larvae, and binding to the nerve chord, was shown by Western blotting. The PI1a/GNA fusion protein also caused mortality when delivered orally to dipteran (Musca domestica; housefly) and hemipteran (Acyrthosiphon pisum; pea aphid) insects, making it a promising candidate for development as a biopesticide.

  17. A recombinant fusion protein containing a spider toxin specific for the insect voltage-gated sodium ion channel shows oral toxicity towards insects of different orders.

    PubMed

    Yang, Sheng; Pyati, Prashant; Fitches, Elaine; Gatehouse, John A

    2014-04-01

    Recombinant fusion protein technology allows specific insecticidal protein and peptide toxins to display activity in orally-delivered biopesticides. The spider venom peptide δ-amaurobitoxin-PI1a, which targets insect voltage-gated sodium channels, was fused to the "carrier" snowdrop lectin (GNA) to confer oral toxicity. The toxin itself (PI1a) and an amaurobitoxin/GNA fusion protein (PI1a/GNA) were produced using the yeast Pichia pastoris as expression host. Although both proteins caused mortality when injected into cabbage moth (Mamestra brassicae) larvae, the PI1a/GNA fusion was approximately 6 times as effective as recombinant PI1a on a molar basis. PI1a alone was not orally active against cabbage moth larvae, but a single 30 μg dose of the PI1a/GNA fusion protein caused 100% larval mortality within 6 days when fed to 3rd instar larvae, and caused significant reductions in survival, growth and feeding in 4th - 6th instar larvae. Transport of fusion protein from gut contents to the haemolymph of cabbage moth larvae, and binding to the nerve chord, was shown by Western blotting. The PI1a/GNA fusion protein also caused mortality when delivered orally to dipteran (Musca domestica; housefly) and hemipteran (Acyrthosiphon pisum; pea aphid) insects, making it a promising candidate for development as a biopesticide. PMID:24486516

  18. Minimally invasive transforaminal lumbosacral interbody fusion.

    PubMed

    Chang, Peng-Yuan; Wang, Michael Y

    2016-07-01

    In minimally invasive spinal fusion surgery, transforaminal lumbar (sacral) interbody fusion (TLIF) is one of the most common procedures that provides both anterior and posterior column support without retraction or violation to the neural structure. Direct and indirect decompression can be done through this single approach. Preoperative plain radiographs and MR scan should be carefully evaluated. This video demonstrates a standard approach for how to perform a minimally invasive transforaminal lumbosacral interbody fusion. The video can be found here: https://youtu.be/bhEeafKJ370 . PMID:27364426

  19. Design of Fusion Safety Data Base

    NASA Astrophysics Data System (ADS)

    Aoki, Isao; Seki, Yasushi

    1994-03-01

    This report presents a data base architecture with its circumstance which is designed to be used for safety design and analysis studies. Design of Fusion Safety Data Base has been carried out to take into account a great number of published references on operation and control of fusion energy and engineering features to secure safety of fusion devices. Data Base of Fiscal Year 1993 - which has been established over an extended year - realized on PC (Personal Computer) peripherals is reported. The concept of data base architecture with its attributive issues and a manipulating way for users are also shown.

  20. Cold-fusion television show angers APS

    NASA Astrophysics Data System (ADS)

    Cartwright, Jon

    2009-06-01

    Cold fusion has been controversial since its inception on 23 March 1989, when chemists Martin Fleischmann and Stanley Pons at the University of Utah in the US announced that they had achieved a sustained nuclear-fusion reaction at room temperature. Two decades on, a US television documentary about the field has stirred up fresh debate after it linked the American Physical Society (APS) to an evaluation of some cold-fusion results by Robert Duncan, a physicist and vice chancellor of the University of Missouri.