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Sample records for 10-24 years result

  1. Homicide rates among persons aged 10-24 years - United States, 1981-2010.

    PubMed

    2013-07-12

    Homicide disproportionately affects persons aged 10-24 years in the United States and consistently ranks in the top three leading causes of death in this age group, resulting in approximately 4,800 deaths and an estimated $9 billion in lost productivity and medical costs in 2010. To investigate trends in homicide among persons aged 10-24 years for the period 1981-2010, CDC analyzed National Vital Statistics System data on deaths caused by homicide of persons in this age group and examined trends by sex, age, race/ethnicity, and mechanism of injury. This report describes the results of that analysis, which indicated that homicide rates varied substantially during the study period, with a sharp rise from 1985 to 1993 followed by a decline that has slowed since 1999. During the period 2000-2010, rates declined for all groups, although the decline was significantly slower for males compared with females and for blacks compared with Hispanics and persons of other racial/ethnic groups. By mechanism of injury, the decline for firearm homicides from 2000 to 2010 was significantly slower than for nonfirearm homicides. The homicide rate among persons aged 10-24 years in 2010 was 7.5 per 100,000, the lowest in the 30-year study period. Primary prevention strategies remain critical, particularly among groups at increased risk for homicide. PMID:23842443

  2. Sexual and reproductive health of persons aged 10-24 years - United States, 2002-2007.

    PubMed

    Gavin, Lorrie; MacKay, Andrea P; Brown, Kathryn; Harrier, Sara; Ventura, Stephanie J; Kann, Laura; Rangel, Maria; Berman, Stuart; Dittus, Patricia; Liddon, Nicole; Markowitz, Lauri; Sternberg, Maya; Weinstock, Hillard; David-Ferdon, Corinne; Ryan, George

    2009-07-17

    This report presents data for 2002-2007 concerning the sexual and reproductive health of persons aged 10-24 years in the United States. Data were compiled from the National Vital Statistics System and multiple surveys and surveillance systems that monitor sexual and reproductive health outcomes into a single reference report that makes this information more easily accessible to policy makers, researchers, and program providers who are working to improve the reproductive health of young persons in the United States. The report addresses three primary topics: 1) current levels of risk behavior and health outcomes; 2) disparities by sex, age, race/ethnicity, and geographic residence; and 3) trends over time. The data presented in this report indicate that many young persons in the United States engage in sexual risk behavior and experience negative reproductive health outcomes. In 2004, approximately 745,000 pregnancies occurred among U.S. females aged <20 years. In 2006, approximately 22,000 adolescents and young adults aged 10-24 years in 33 states were living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS), and approximately 1 million adolescents and young adults aged 10-24 years were reported to have chlamydia, gonorrhea, or syphilis. One-quarter of females aged 15-19 years and 45% of those aged 20-24 years had evidence of infection with human papillomavirus during 2003-2004, and approximately 105,000 females aged 10--24 years visited a hospital emergency department (ED) for a nonfatal sexual assault injury during 2004-2006. Although risks tend to increase with age, persons in the youngest age group (youths aged 10--14 years) also are affected. For example, among persons aged 10-14 years, 16,000 females became pregnant in 2004, nearly 18,000 males and females were reported to have sexually transmitted diseases (STDs) in 2006, and 27,500 females visited a hospital ED because of a nonfatal sexual assault injury during 2004

  3. 19 CFR 10.24 - Documentation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Documentation. 10.24 Section 10.24 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... with United States Components § 10.24 Documentation. (a) Documents required. The following...

  4. 19 CFR 10.24 - Documentation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Documentation. 10.24 Section 10.24 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. General Provisions Articles Assembled Abroad with United States Components §...

  5. 19 CFR 10.24 - Documentation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Documentation. 10.24 Section 10.24 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. General Provisions Articles Assembled Abroad with United States Components §...

  6. 19 CFR 10.24 - Documentation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Documentation. 10.24 Section 10.24 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. General Provisions Articles Assembled Abroad with United States Components §...

  7. 19 CFR 10.24 - Documentation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Documentation. 10.24 Section 10.24 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. General Provisions Articles Assembled Abroad with United States Components §...

  8. 27 CFR 10.24 - Sales promotion contests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Sales promotion contests. 10.24 Section 10.24 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS COMMERCIAL BRIBERY Commercial Bribery § 10.24 Sales promotion...

  9. 17 CFR 10.24 - Amendments and supplemental pleadings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Amendments and supplemental pleadings. 10.24 Section 10.24 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION RULES OF PRACTICE Institution of Adjudica- tory Proceedings; Pleadings; Motions § 10.24 Amendments and supplemental pleadings. (a) Complaint...

  10. Nebraska wind resource assessment first year results

    SciTech Connect

    Hurley, P.J.F.; Vilhauer, R.; Stooksbury, D.

    1996-12-31

    This paper presents the preliminary results from a wind resource assessment program in Nebraska sponsored by the Nebraska Power Association. During the first year the measured annual wind speed at 40 meters ranged from 6.5 - 7.5 m/s (14.6 - 16.8 mph) at eight stations across the state. The site selection process is discussed as well as an overview of the site characteristics at the monitoring locations. Results from the first year monitoring period including data recovery rate, directionality, average wind speeds, wind shear, and turbulence intensity are presented. Results from the eight sites are qualitatively compared with other midwest and west coast locations. 5 figs., 2 tabs.

  11. Results from the International Heliophysical Year (IHY)

    NASA Technical Reports Server (NTRS)

    Davila, Joseph M.

    2010-01-01

    The International Heliophysical Year (IHY) involved the effort of thousands of scientists from over 70 countries, ended in February 2009. The major objectives of the IHY included over 60 collaborative studies of universal physical processes in the solar system, the deployment of arrays of small instruments to observe heliophysical processes, a unique program of educational and public outreach, and the preservation of the history of the IGY, during a two year period. A follow on effort, the International Space Weather Initiative (ISWI) is designed to build on the momentum developed during the IHY to develop the capability to observe, understand, and predict space weather phenomena.

  12. Fermi GBM: Results from the First Year +

    NASA Technical Reports Server (NTRS)

    Wilson-Hodge, Colleen A.

    2009-01-01

    Gamma-ray Burst Monitor (GBM) has performed well in the first year+. GBM triggers 353 Gamma-ray Bursts (GRBs), 168 SGR events, 18 TGFs, and 1 solar flare to date. Short GRBs appear contracted in time and shifted to higher energy than long GRBs. Pulsed persistent emission from SGR 1550-5418 detected. TGFs are shorter, have higher average photon energies, and much higher count rates than GRBs. GBM monitoring of accreting pulsars provides long-term spin-histories. GBM Earth occultation monitoring complements Swift.

  13. Tunka-133: Results of 3 year operation

    NASA Astrophysics Data System (ADS)

    Prosin, V. V.; Berezhnev, S. F.; Budnev, N. M.; Chiavassa, A.; Chvalaev, O. A.; Gress, O. A.; Dyachok, A. N.; Epimakhov, S. N.; Karpov, N. I.; Kalmykov, N. N.; Konstantinov, E. N.; Korobchenko, A. V.; Korosteleva, E. E.; Kozhin, V. A.; Kuzmichev, L. A.; Lubsandorzhiev, B. K.; Lubsandorzhiev, N. B.; Mirgazov, R. R.; Panasyuk, M. I.; Pan'kov, L. V.; Popova, E. G.; Ptuskin, V. S.; Semeney, Yu. A.; Silaev, A. A.; Silaev, A. A.; Skurikhin, A. V.; Spiering, C.; Sveshnikova, L. G.; Yashin, I. V.; Zagorodnikov, A. V.

    2014-08-01

    The EAS Cherenkov light array Tunka-133, with ~3 km2 geometric area, is taking data since 2009. The array permits a detailed study of cosmic ray energy spectrum and mass composition in the PeV energy range. After a short description of the methods of EAS parameter reconstruction, we present the all-particle energy spectrum and results of studying CR composition, based on 3 seasons of array operation. In the last part of the paper, we discuss possible interpretations of the obtained results.

  14. Personal Access Satellite System (PASS) study. Fiscal year 1989 results

    NASA Technical Reports Server (NTRS)

    Sue, Miles K. (Editor)

    1990-01-01

    The Jet Propulsion Laboratory is exploring the potential and feasibility of a personal access satellite system (PASS) that will offer the user greater freedom and mobility than existing or currently planned communications systems. Studies performed in prior years resulted in a strawman design and the identification of technologies that are critical to the successful implementation of PASS. The study efforts in FY-89 were directed towards alternative design options with the objective of either improving the system performance or alleviating the constraints on the user terminal. The various design options and system issues studied this year and the results of the study are presented.

  15. Aquifer Sampling Tube Results for Fiscal Year 2003

    SciTech Connect

    Hartman, Mary J.; Peterson, Robert E.

    2003-10-27

    This report presents and discusses results of the fiscal year 2003 sampling event associated with aquifer tubes along the Columbia River in the northern Hanford Site. Aquifer tube data help define the extent of groundwater contamination near the river, determine vertical variations in contamination, monitor the performance of interim remedial actions near the river, and support impact studies.

  16. Reading Recovery Program Implementation Year Three, School Year 1992-1993. Report of Results and Effectiveness.

    ERIC Educational Resources Information Center

    Schotanus, Helen; And Others

    A study examined the results and effectiveness of the third year of the Reading Recovery program in New Hampshire. With the 50 Reading Recovery teachers from previous classes, 32 teachers in the new class, and 3 teacher leaders, a total of 85 teachers taught Reading Recovery during the 1992-93 school year. A total of 422 first-grade children…

  17. Reading Recovery Program Implementation Year Six, School Year 1995-96. Report of Results and Effectiveness.

    ERIC Educational Resources Information Center

    Schotanus, Helen; And Others

    A study examined the results and effectiveness of the sixth year of the Reading Recovery program in New Hampshire. With the 95 Reading Recovery teachers from previous classes, 38 teachers in the new class, and 4 teacher leaders, a total of 137 teachers taught Reading Recovery during the 1995-96 school year. A total of 693 first-grade children…

  18. Reading Recovery Program Implementation Year Five, School Year 1994-95. Report of Results and Effectiveness.

    ERIC Educational Resources Information Center

    Schotanus, Helen; And Others

    A study examined the results and effectiveness of the fifth year of the Reading Recovery program in New Hampshire. With the 78 Reading Recovery teachers from previous classes, 23 teachers in the new class, and 3 teacher leaders, a total of 104 teachers taught Reading Recovery during the 1994-95 school year. A total of 530 first-grade children…

  19. Results in Assisted Peritoneal Dialysis: A Ten-Year Experience

    PubMed Central

    Querido, Sara; Branco, Patrícia Quadros; Costa, Elisabete; Pereira, Sara; Gaspar, Maria Augusta; Barata, José Diogo

    2015-01-01

    Background/Aims. Peritoneal dialysis is a successful renal replacement therapy (RRT) for old and dependent patients. We evaluated the clinical outcomes of an assisted peritoneal dialysis (aPD) program developed in a Portuguese center. Methods. Retrospective study based on 200 adult incident patients admitted during ten years to a PD program. We included all 17 patients who were under aPD and analysed various parameters, including complications with the technique, hospitalizations, and patient and technique survival. Results. The global peritonitis rate was lower in helped than in nonhelped patients: 0.4 versus 0.59 episodes/patient/year. The global hospitalization rate was higher in helped than in nonhelped patients: 0.67 versus 0.45 episodes/patient/year (p = NS). Technique survival in helped patients versus nonhelped patients was 92.3%, 92.3%, 83.1%, and 72.7% versus 91.9%, 81.7%, and 72.1%, and 68.3%, at 1, 2, 3, and 4 years, respectively (p = NS), and patient survival in helped patients versus nonhelped patients was 93.3%, 93.3%, 93.3%, and 74.7% versus 95.9% 93.7%, 89%, and 82% at 1, 2, 3, and 4 years, respectively (p = NS). Conclusions. aPD offers an opportune, reliable, and effective home care alternative for patients with no other RRT options. PMID:26600950

  20. Results in Assisted Peritoneal Dialysis: A Ten-Year Experience.

    PubMed

    Querido, Sara; Branco, Patrícia Quadros; Costa, Elisabete; Pereira, Sara; Gaspar, Maria Augusta; Barata, José Diogo

    2015-01-01

    Background/Aims. Peritoneal dialysis is a successful renal replacement therapy (RRT) for old and dependent patients. We evaluated the clinical outcomes of an assisted peritoneal dialysis (aPD) program developed in a Portuguese center. Methods. Retrospective study based on 200 adult incident patients admitted during ten years to a PD program. We included all 17 patients who were under aPD and analysed various parameters, including complications with the technique, hospitalizations, and patient and technique survival. Results. The global peritonitis rate was lower in helped than in nonhelped patients: 0.4 versus 0.59 episodes/patient/year. The global hospitalization rate was higher in helped than in nonhelped patients: 0.67 versus 0.45 episodes/patient/year (p = NS). Technique survival in helped patients versus nonhelped patients was 92.3%, 92.3%, 83.1%, and 72.7% versus 91.9%, 81.7%, and 72.1%, and 68.3%, at 1, 2, 3, and 4 years, respectively (p = NS), and patient survival in helped patients versus nonhelped patients was 93.3%, 93.3%, 93.3%, and 74.7% versus 95.9% 93.7%, 89%, and 82% at 1, 2, 3, and 4 years, respectively (p = NS). Conclusions. aPD offers an opportune, reliable, and effective home care alternative for patients with no other RRT options. PMID:26600950

  1. The TAOS Project: Results from Seven Years of Survey Data

    NASA Astrophysics Data System (ADS)

    Zhang, Z.-W.; Lehner, M. J.; Wang, J.-H.; Wen, C.-Y.; Wang, S.-Y.; King, S.-K.; Granados, Á. P.; Alcock, C.; Axelrod, T.; Bianco, F. B.; Byun, Y.-I.; Chen, W. P.; Coehlo, N. K.; Cook, K. H.; de Pater, I.; Kim, D.-W.; Lee, T.; Lissauer, J. J.; Marshall, S. L.; Protopapas, P.; Rice, J. A.; Schwamb, M. E.

    2013-07-01

    The Taiwanese-American Occultation Survey (TAOS) aims to detect serendipitous occultations of stars by small (~1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (<10-3 events per star per year) and short in duration (~200 ms), so many stars must be monitored at a high readout cadence. TAOS monitors typically ~500 stars simultaneously at a 5 Hz readout cadence with four telescopes located at Lulin Observatory in central Taiwan. In this paper, we report the results of the search for small Kuiper Belt objects (KBOs) in seven years of data. No occultation events were found, resulting in a 95% c.l. upper limit on the slope of the faint end of the KBO size distribution of q = 3.34-3.82, depending on the surface density at the break in the size distribution at a diameter of about 90 km.

  2. THE TAOS PROJECT: RESULTS FROM SEVEN YEARS OF SURVEY DATA

    SciTech Connect

    Zhang, Z.-W.; Lehner, M. J.; Wang, J.-H.; Wen, C.-Y.; Wang, S.-Y.; King, S.-K.; Cook, K. H.; Lee, T.; Granados, A. P.; Alcock, C.; Protopapas, P.; Axelrod, T.; Bianco, F. B.; Byun, Y.-I.; Chen, W. P.; Coehlo, N. K.; De Pater, I.; Kim, D.-W.; Lissauer, J. J.; Marshall, S. L.; and others

    2013-07-01

    The Taiwanese-American Occultation Survey (TAOS) aims to detect serendipitous occultations of stars by small ({approx}1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (<10{sup -3} events per star per year) and short in duration ({approx}200 ms), so many stars must be monitored at a high readout cadence. TAOS monitors typically {approx}500 stars simultaneously at a 5 Hz readout cadence with four telescopes located at Lulin Observatory in central Taiwan. In this paper, we report the results of the search for small Kuiper Belt objects (KBOs) in seven years of data. No occultation events were found, resulting in a 95% c.l. upper limit on the slope of the faint end of the KBO size distribution of q = 3.34-3.82, depending on the surface density at the break in the size distribution at a diameter of about 90 km.

  3. Long Term Corrosion/Degradation Test Six Year Results

    SciTech Connect

    M. K. Adler Flitton; C. W. Bishop; M. E. Delwiche; T. S. Yoder

    2004-09-01

    The Subsurface Disposal Area (SDA) of the Radioactive Waste Management Complex (RWMC) located at the Idaho National Engineering and Environmental Laboratory (INEEL) contains neutron-activated metals from non-fuel, nuclear reactor core components. The Long-Term Corrosion/Degradation (LTCD) Test is designed to obtain site-specific corrosion rates to support efforts to more accurately estimate the transfer of activated elements to the environment. The test is using two proven, industry-standard methods—direct corrosion testing using metal coupons, and monitored corrosion testing using electrical/resistance probes—to determine corrosion rates for various metal alloys generally representing the metals of interest buried at the SDA, including Type 304L stainless steel, Type 316L stainless steel, Inconel 718, Beryllium S200F, Aluminum 6061, Zircaloy-4, low-carbon steel, and Ferralium 255. In the direct testing, metal coupons are retrieved for corrosion evaluation after having been buried in SDA backfill soil and exposed to natural SDA environmental conditions for times ranging from one year to as many as 32 years, depending on research needs and funding availability. In the monitored testing, electrical/resistance probes buried in SDA backfill soil will provide corrosion data for the duration of the test or until the probes fail. This report provides an update describing the current status of the test and documents results to date. Data from the one-year and three-year results are also included, for comparison and evaluation of trends. In the six-year results, most metals being tested showed extremely low measurable rates of general corrosion. For Type 304L stainless steel, Type 316L stainless steel, Inconel 718, and Ferralium 255, corrosion rates fell in the range of “no reportable” to 0.0002 mils per year (MPY). Corrosion rates for Zircaloy-4 ranged from no measurable corrosion to 0.0001 MPY. These rates are two orders of magnitude lower than those specified in

  4. Prone Breast Intensity Modulated Radiation Therapy: 5-Year Results

    SciTech Connect

    Osa, Etin-Osa O.; DeWyngaert, Keith; Roses, Daniel; Speyer, James; Guth, Amber; Axelrod, Deborah; Fenton Kerimian, Maria; Goldberg, Judith D.; Formenti, Silvia C.

    2014-07-15

    Purpose: To report the 5-year results of a technique of prone breast radiation therapy delivered by a regimen of accelerated intensity modulated radiation therapy with a concurrent boost to the tumor bed. Methods and Materials: Between 2003 and 2006, 404 patients with stage I-II breast cancer were prospectively enrolled into 2 consecutive protocols, institutional trials 03-30 and 05-181, that used the same regimen of 40.5 Gy/15 fractions delivered to the index breast over 3 weeks, with a concomitant daily boost to the tumor bed of 0.5 Gy (total dose 48 Gy). All patients were treated after segmental mastectomy and had negative margins and nodal assessment. Patients were set up prone: only if lung or heart volumes were in the field was a supine setup attempted and chosen if found to better spare these organs. Results: Ninety-two percent of patients were treated prone, 8% supine. Seventy-two percent had stage I, 28% stage II invasive breast cancer. In-field lung volume ranged from 0 to 228.27 cm{sup 3}, mean 19.65 cm{sup 3}. In-field heart volume for left breast cancer patients ranged from 0 to 21.24 cm{sup 3}, mean 1.59 cm{sup 3}. There was no heart in the field for right breast cancer patients. At a median follow-up of 5 years, the 5-year cumulative incidence of isolated ipsilateral breast tumor recurrence was 0.82% (95% confidence interval [CI] 0.65%-1.04%). The 5-year cumulative incidence of regional recurrence was 0.53% (95% CI 0.41%-0.69%), and the 5-year overall cumulative death rate was 1.28% (95% CI 0.48%-3.38%). Eighty-two percent (95% CI 77%-85%) of patients judged their final cosmetic result as excellent/good. Conclusions: Prone accelerated intensity modulated radiation therapy with a concomitant boost results in excellent local control and optimal sparing of heart and lung, with good cosmesis. Radiation Therapy Oncology Group protocol 1005, a phase 3, multi-institutional, randomized trial is ongoing and is evaluating the equivalence of a similar dose and

  5. Physical activity across the curriculum: year one process evaluation results

    PubMed Central

    Gibson, Cheryl A; Smith, Bryan K; DuBose, Katrina D; Greene, J Leon; Bailey, Bruce W; Williams, Shannon L; Ryan, Joseph J; Schmelzle, Kristin H; Washburn, Richard A; Sullivan, Debra K; Mayo, Matthew S; Donnelly, Joseph E

    2008-01-01

    Background Physical Activity Across the Curriculum (PAAC) is a 3-year elementary school-based intervention to determine if increased amounts of moderate intensity physical activity performed in the classroom will diminish gains in body mass index (BMI). It is a cluster-randomized, controlled trial, involving 4905 children (2505 intervention, 2400 control). Methods We collected both qualitative and quantitative process evaluation data from 24 schools (14 intervention and 10 control), which included tracking teacher training issues, challenges and barriers to effective implementation of PAAC lessons, initial and continual use of program specified activities, and potential competing factors, which might contaminate or lessen program effects. Results Overall teacher attendance at training sessions showed exceptional reach. Teachers incorporated active lessons on most days, resulting in significantly greater student physical activity levels compared to controls (p < 0.0001). Enjoyment ratings for classroom-based lessons were also higher for intervention students. Competing factors, which might influence program results, were not carried out at intervention or control schools or were judged to be minimal. Conclusion In the first year of the PAAC intervention, process evaluation results were instrumental in identifying successes and challenges faced by teachers when trying to modify existing academic lessons to incorporate physical activity. PMID:18606013

  6. Modified Mandibulotomy Technique to Reduce Postoperative Complications: 5-Year Results

    PubMed Central

    Na, Hye-Young; Choi, Eun-Joo; Kim, Hyung Jun; Cha, In-Ho

    2013-01-01

    Purpose To review the 5-year outcomes of our modified mandibulotomy technique. Retrospective review of a tertiary level oral cancer center. Materials and Methods During a 5-year period, 30 patients who had a uniform surgical technique consisting of a lower lip-splitting, modified stair-step osteotomy with thin saw blade and osteotome after plate-precontouring and combination fixation with monocortical osteosynthesis (miniplate) and bicortical osteosynthesis (maxiplate and bicortical screws), with at least 14 months postoperative follow-up, were selected and reviewed retrospectively. Results There were 8 women and 22 men with an average age of 56.5 years. All the patients involved malignancies were squamous cell carcinoma. The main primary sites of the those who underwent a mandibulotomy were the tonsil, the base of tongue, the oral tongue, the retromolar pad area, and others. Others included buccal cheek, floor of mouth, and soft palate. 23 patients received postoperative radiation therapy, and among whom 8 patients also received chemotherapy. Total four (13%) mandibulotomy-related complications occurred, only two (6.7%) requiring additional operation under general anesthesia. Conclusion Our modified mandibulotomy meets the criteria for an ideal mandibulotomy technique relatively well because it requires no intermaxillary fixation, can precise preserve the occlusion in a precise way, allows early function, requires no secondary procedures, and has few complications. PMID:23918577

  7. Clinical outcomes of pars plicata anterior vitrectomy: 2-year results

    PubMed Central

    Narang, Priya; Agarwal, Amar

    2015-01-01

    Purpose: To demonstrate the safety and outcome of a surgical approach that uses pars plicata site for anterior vitrectomy during phacoemulsification procedure complicated by posterior capsule rupture and residual cortical matter. Design: Single center, retrospective, interventional, noncomparative study. Materials and Methods: Medical records of a consecutive series of 35 eyes of 35 patients who underwent pars plicata anterior vitrectomy (PPAV) were reviewed. The main outcome measures were corrected and uncorrected distance visual acuity (CDVA, UDVA), early and late postoperative complications and intraocular pressure (IOP). Ultrasound biomicroscopic (UBM) evaluation of sclerotomy site and spectral domain optical coherence tomography analysis for central macular thickness (CMT) was performed. The final visual outcome at 2 years was evaluated. Results: At 2 years follow-up, the mean postoperative UDVA (logarithm of the minimum angle of resolution [logMAR]) and CDVA (logMAR) was 0.49 ± 0.26 and 0.19 ± 0.14, respectively. There was no significant change in the IOP (P = 0.061) and the mean CMT at 2 years was 192.5 ± 5.54 μm. The postoperative UBM image of the sclerotomy site at 8 weeks demonstrated a clear wound without any vitreous adhesion or incarceration. Intraoperative hyphema was seen in 1 (2.8%) case and postoperative uveitis was seen in 2 (5.7%) cases, which resolved with medications. No case of an iatrogenic retinal break or retinal detachment was reported. Conclusions: PPAV enables a closed chamber approach, allows thorough cleanup of vitreous in the pupillary plane and anterior chamber and affords better access to the subincisional and retropupillary cortical remnant with a significant visual outcome and an acceptable complication rate. PMID:26632124

  8. Field Lysimeter Test Facility: Second year (FY 1989) test results

    SciTech Connect

    Campbell, M.D.; Gee, G.W.; Kanyid, M.J.; Rockhold, M.L.

    1990-04-01

    The Record of Decision associated with the Hanford Defense Waste Environmental Impact Statement (53 FR 12449-53) commits to an evaluation of the use of protective barriers placed over near-surface wastes. The barrier must protect against wind and water erosion and limit plant and animal intrusion and infiltration of water. Successful conclusion of this program will yield the necessary protective barrier design for near-surface waste isolation. This report presents results from the second year of tests at the FLTF. The primary objective of testing protective barriers at the FLTF was to measure the water budgets within the various barriers and assess the effectiveness of their designs in limiting water intrusion into the zone beneath each barrier. Information obtained from these measurements is intended for use in refining barrier designs. Four elements of water budget were measured during the year: precipitation, evaporation, storage, and drainage. Run-off, which is a fifth element of a complete water budget, was made negligible by a lip on the lysimeters that protrudes 5 cm above the soil surface to prevent run-off. A secondary objective of testing protective barriers at the FLTF was to refine procedures and equipment to support data collection for verification of the computer model needed for long-term projections of barrier performance. 6 refs.

  9. Results of Detailed Hydrologic Characterization Tests - Fiscal Year 2000

    SciTech Connect

    Spane, Frank A; Thorne, Paul D; Newcomer, Darrell R

    2001-05-15

    This report provides the results of detailed hydrologic characterization tests conducted within eleven Hanford Site wells during fiscal year 2000. Detailed characterization tests performed included groundwater-flow characterization; barometric response evaluation; slug tests; single-well tracer tests; constant-rate pumping tests; and in-well, vertical flow tests. Hydraulic property estimates obtained from the detailed hydrologic tests include transmissivity; hydraulic conductivity; specific yield; effective porosity; in-well, lateral flow velocity; aquifer-flow velocity; vertical distribution of hydraulic conductivity (within the well-screen section); and in-well, vertical flow velocity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for four sites where detailed well testing was performed.

  10. FOUR YEARS OF OPERATIONS AND RESULTS WITH FORTE

    SciTech Connect

    D. ROUSSEL-DUPRE; P. KLINGNER; L. CARLSON; ET AL

    2001-06-01

    The FORTE (Fast Onboard Recording of Transient Events) satellite was launched on 29 August 1997 and has been in continuous operation since that time. FORTE was placed in a nearly circular, 825-km-altitude, 70 degrees inclination orbit by a Pegasus rocket funded by Air Force Space Test Program. The Department of Energy funded the FORTE satellite, which was designed and built at Los Alamos. FORTE's successful launch and engineered robustness were a result of several years of dedicated work by the joint Los Alamos National Laboratory/Sandia National Laboratory project team, led through mission definition, payload and satellite development, and launch by Dr. Stephen Knox. The project is now led by Dr. Abram Jacobson. FORTE carries a suite of instruments, an optical system and a rf system, for the study of lightning and anthropogenic signals. As a result of this effort, new understandings of lightning events have emerged as well as a more complete understanding of the relationship between optical and rf lightning events. This paper will provide an overview of the FORTE satellite and will discuss the on orbit performance of the subsystems.

  11. Four years of operations and results with FORTE

    SciTech Connect

    Klingner, P. L.; Carlson, L. D.; Dingler, R. D.; Esch-Mosher, D. M.; Jacobson, A. R.; Roussel-Dupre, D.

    2001-01-01

    The FORTE (Fast Onboard Recording of Transient Events) satellite was launched on 29 August 1997 and has been in continuous operation since that time. FORTE was placed in a nearly circular, 825-km-altitude, 70 degrees inclination orbit by a Pegasus rocket funded by Air Force Space Test Program. The Department of Energy funded the FORTE satellite, which was designed and built at Los Alamos. FORTE's successful launch and engineered robustness were a result of several years of dedicated work by the joint Los Alamos National Laboratory/Sandia National Laboratory project team, led through mission definition, payload and satellite development, and launch by Dr. Stephen Knox. The project is now led by Dr. Abram Jacobson. FORTE carries a suite of instruments, an optical system and a rf system, for the study of lightning and anthropogenic signals. As a result of this effort, new understandings of lightning events have emerged as well as a more complete understanding of the relationship between optical and rf lightning events. This paper will provide an overview of the FORTE satellite and will discuss the on orbit performance of the subsystems.

  12. Near-Earth Asteroid Tracking (NEAT): First Year Results

    NASA Astrophysics Data System (ADS)

    Helin, E. F.; Rabinowitz, D. L.; Pravdo, S. H.; Lawrence, K. J.

    1997-07-01

    The successful detection of Near-Earth Asteroids (NEAs) has been demonstrated by the Near-Earth Asteroid Tracking (NEAT) program at the Jet Propulsion Laboratory during its first year of operation. The NEAT CCD camera system is installed on the U. S. Air Force 1-m GEODSS telescope in Maui. Using state-of-the-art software and hardware, the system initiates nightly transmitted observing script from JPL, moves the telescopes for successive exposures of the selected fields, detects moving objects as faint as V=20.5 in 40 s exposures, determines their astrometric positions, and downloads the data for review at JPL in the morning. The NEAT system is detecting NEAs larger than 200m, comets, and other unique objects at a rate competitive with current operating systems, and bright enough for important physical studies on moderate-sized telescopes. NEAT has detected over 10,000 asteroids over a wide range of magnitudes, demonstrating the excellent capability of the NEAT system. Fifty-five percent of the detections are new objects and over 900 of them have been followed on a second night to receive designation from the Minor Planet Center. 14 NEAs (9 Amors, 4 Apollos, and 1 Aten) have been discovered since March 1996. Also, 2 long period comets and 1996 PW, an asteroidal object with an orbit of a long-period comet, with an eccentricity of 0.992 and orbital period of 5900 years. Program discoveries will be reviewed along with analysis of results pertaining to the discovery efficiency, distribution on the sky, range of orbits and magnitudes. Related abstract: Lawrence, K., et al., 1997 DPS

  13. Bonded amalgam sealants: two-year clinical results.

    PubMed

    Staninec, M; Eakle, W S; Silverstein, S; Marshall, G W; Artiga, N

    1998-03-01

    The authors used bonded amalgams as pit and fissure sealants without mechanical preparation. They compared the two-year retention of the bonded amalgams with that of resin-based pit and fissure sealants. Clinical examinations at six months, one year and two years revealed no difference between the retention of the two sealants. This technique opens up the possibility of using bonded amalgam in pits and fissures surrounding very conservative preparations in a preventive amalgam restoration. PMID:9529807

  14. Cementless bulk alumina socket: preliminary results at 6 years.

    PubMed

    Hamadouche, M; Nizard, R S; Meunier, A; Bizot, P; Sedel, L

    1999-09-01

    To avoid polyethylene wear observed in total hip replacement, an alumina-alumina combination has been used since 1977. The aim of this study is to report the results of a hybrid alumina-alumina total hip arthroplasty with a cementless press-fit bulk alumina socket and a cemented titanium alloy stem in 55 patients (62 hips) operated on between 1982 and 1990. The bearing surfaces were a 32-mm alumina head articulating within the alumina socket. Four failures occurred: 3 aseptic loosenings of the socket and 1 femoral head fracture. Considering aseptic loosening as the endpoint, the survival rate was 93.2% after 6 years. At a mean of 72.1 months' follow-up, 92.4% of the surviving hips were graded as very good or good using the Merle d'Aubigné-Postel hip score. Radiolucent lines were observed on the acetabular side in 68.1 of the hips. The future of this interface, which is probably fibrous, remains questionable. With the exception of 1 femoral head fracture, all revisions were related to failure of the bony fixation of the socket, and no problem was encountered related to the alumina-alumina friction coupling. Alumina sockets with other types of cementless fixation have therefore been designed and are presently under clinical investigation. PMID:10512442

  15. Malaria transmission in Libreville: results of a one year survey

    PubMed Central

    2012-01-01

    Background In Gabon, vector transmission has been poorly studied. Since the implementation of the Roll Back malaria recommendations, clinical studies have shown a decline in the burden of malaria in Libreville, the capital city of Gabon. To better understand the transmission dynamic in Libreville, an entomological survey was conducted in five districts of the city. Methods Mosquitoes were sampled by human landing collection during 1 year in five districts of Libreville: Alibandeng, Beauséjour, Camp des Boys and Sotega. Mosquitoes were identified morphologically and by molecular methods. The Plasmodium falciparum circumsporozoïte indices were measured by ELISA, and the entomological inoculation rates (EIR) were calculated for all areas. Molecular assessments of pyrethroid knock down resistance (kdr) and of insensitive acetylcholinesterase resistance were conducted. Results A total of 57,531 mosquitoes were caught during 341 person-nights (161 person-nights indoor and 180 person-nights outdoor) among which, 4,223 were Anopheles gambiae s.l. The average Human Biting Rate fell from 15.5 bites per person during the rainy season to 4.7 during the dry season. The An. gambiae complex population was composed of An. gambiae s.s molecular form S (99.5%), Anopheles melas (0.3%) and An. gambiae s.s. form M (0.2%). Thirty-three out of 4,223 An. gambiae s.l. were found to be infected by P. falciparum (CSP index = 0.78%). The annual EIR was estimated at 33.9 infected bites per person per year ranging from 13 in Alibandeng to 88 in Sotega. No insensitive AChE mutation was identified but both kdr-w and kdr-e mutations were present in An. gambiae molecular form S with a higher frequency of the kdr-w allele (76%) than the kdr-e allele (23.5%). Conclusion Malaria transmission in Libreville occurred mainly during the rainy season but also during the dry season in the five districts. Transmission level is high and seems to be very heterogeneous in the town. Interestingly, the highest

  16. Illinois Community College System Results Report, Fiscal Year 2002.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    This report details the ways in which the Illinois Community College System is addressing its strategic plan, "Promise for Illinois," for fiscal year 2002. Illinois has 39 community college districts and one multi-community college center that serve nearly one million students a year. The report identifies the following six goals: (1) economic…

  17. Astronomers celebrate a year of new Hubble results

    NASA Astrophysics Data System (ADS)

    1995-02-01

    Space Telescope to make accurate measurements of the distance of Ml 00, a far away galaxy located in the Virgo cluster of galaxies. To do this they used a number of Cepheid variable stars, rare objects that change in brightness over a regular period. Because astronomers know that there is a direct link between the period of the Cepheid's pulsation and its actual brightness, they can do a simple calculation to work out the distance to the object by comparing its actual brightness with how bright it appears to Hubble. The astronomers had to study more than 40,000 stars before finding the 20 Cepheids they used for their calculations. The results revealed that M100 lies 56 million light years from Earth. With this, astronomers calculated that the Universe is expanding at a rate of 80 kilometres per second per megaparsec (a megaparsec is 3,261,600 light years). This is much faster than astronomers had expected. On the basis of this value for the Hubble Constant, the Universe must be aged somewhere between eight and twelve billion years old. But, this flies in the face of established facts. We know there are stars in our Universe that are 16 billion years old - how can they be older than the Universe in which they exist? It could be that the theory that explains the evolution of stars or the Big Bang theory are wrong. Or perhaps it is the observations that are incorrect. Hubble astronomers soon hope to solve this riddle by taking further measurements to refine their figures. "This is a programme that we know is going to give us some really firm answers in the next three to five years," said Dr Macchetto, one of the 15 European astronomers at the Space Telescope Science Institute. "It will take that time to collect and analyse enough data." Part of the Universe is missing ! Once astronomers know the expansion rate of the Universe they will be one step away from determining its fate. But it will be a big step - for astronomers will have to work out the mass of the Universe and

  18. The functional and oncological results after scapulectomy for scapular tumours: 2–16-year results

    PubMed Central

    Mohanlal, P.; Bose, J. C.; Gangadharan, R.; Karthisundar, V.

    2006-01-01

    Twenty-five patients underwent scapulectomy for various tumours between 1989 and 2005. We describe 23 patients with scapular tumours who were followed-up for a minimum of 2 years after scapulectomy. The average age was 29 years, and two-thirds of the patients were male. Nineteen patients had malignant neoplasms, of which chondrosarcoma was most common, followed by Ewing’s sarcoma. Surgical staging was by Enneking’s system, with stage IIB being the most frequent. Fifteen patients underwent total scapulectomy, and the rest had their glenoid retained. With an average follow-up period of 66.7 months (23–202 months), functional and oncological outcomes were evaluated for all patients. Two patients had superficial wound infections requiring antibiotics, and one had skin necrosis requiring skin cover. Functional outcome was satisfactory in 13 patients. Cosmetically and emotionally acceptable surgery, scapulectomy made 19 patients continuously disease free, while four patients died of disease. The 5-year survival rate of 19 patients with malignant tumours was 75.9%. Retention of the glenohumeral articulation (subtotal) resection gives superior functional results. PMID:17043860

  19. 2 Years of Science, One-of-a-Kind Results

    ERIC Educational Resources Information Center

    Ashburn, Elyse

    2007-01-01

    Fourteen years ago, Bruce A. Jackson was doing his postdoctoral work at the Boston University School of Medicine and working nights teaching at nearby Roxbury Community College. But his exhausting shuttle between two colleges was about to come to an end. Mr. Jackson, a biochemist, had recently received word from the National Science Foundation…

  20. The International Geophysical Year in Antarctica: Uncommon Collaborations, Unprecedented Results

    ERIC Educational Resources Information Center

    Belanger, Dian Olson

    2004-01-01

    When 1 July 1957 ''dawned'' in the dark of the south polar night, Americans at seven scientific stations scattered across Antarctica officially began systematic, synoptic observations of the air above and ice below. Joining scientists from 11 other countries on the polar continent, they were part of the International Geophysical Year, an 18-month…

  1. Comparing Ultraviolet Spectra against Calculations: Year 2 Results

    NASA Technical Reports Server (NTRS)

    Peterson, Ruth C.

    2004-01-01

    The five-year goal of this effort is to calculate high fidelity mid-W spectra for individual stars and stellar systems for a wide range of ages, abundances, and abundance ratios. In this second year, the comparison of our calculations against observed high-resolution mid- W spectra was extended to stars as metal-rich as the Sun, and to hotter and cooler stars, further improving the list of atomic line parameters used in the calculations. We also published the application of our calculations based on the earlier list of line parameters to the observed mid-UV and optical spectra of a mildly metal-poor globular cluster in the nearby Andromeda galaxy, Messier 3 1.

  2. The VVV Survey of the Milky Way: first year results

    NASA Astrophysics Data System (ADS)

    Minniti, D.; Clariá, J. J.; Saito, R. K.; Hempel, M.; Lucas, P. W.; Rejkuba, M.; Toledo, I.; Gonzalez, O. A.; Alonso-García, J.; Irwin, M. J.; Gonzalez-Solares, E.; Cross, N.; Ivanov, V. D.; Soto, M.; Dékány, I.; Angeloni, R.; Catelan, M.; Amôres, E. B.; Gurovich, S.; Emerson, J. P.; Lewis, J.; Hodgkin, S.; Pietrukowicz, P.; Zoccali, M.; Sale, S. E.; Barbá, R.; Barbuy, B.; Beamin, J. C.; Helminiak, K.; Borissova, J.; Folkes, S. L.; Gamen, R. C.; Geisler, D.; Mauro, F.; Chené, A.-N.; Alonso, M. V.; Gunthardt, G.; Hanson, M.; Kerins, E.; Kurtev, R.; Majaess, D.; Martín, E.; Masetti, N.; Mirabel, I. F.; Monaco, L.; Moni Bidin, C.; Padilla, N.; Rojas, A.; Pietrzynski, G.; Saviane, I.; Valenti, E.; Weidmann, W.; López-Corredoira, M.; Ahumada, A. V.; Aigrain, S.; Arias, J. I.; Bica, E.; Bandyopadhyay, R. M.; Baume, G.; Bedin, L. R.; Bonatto, C.; Bronfman, L.; Carraro, G.; Contreras, C.; Davis, C. J.; de Grijs, R.; Dias, B.; Drew, J. E.; Fariña, C.; Feinstein, C.; Fernández Lajús, E.; Gieren, W.; Goldman, B.; Gosling, A.; Hambly, N. C.; Hoare, M.; Jordán, A.; Kinemuchi, K.; Maccarone, T.; Merlo, D. C.; Mennickent, R. E.; Morelli, L.; Motta, V.; Palma, T.; Popescu, B.; Parisi, M. C.; Parker, Q.; Pignata, G.; Read, M. A.; Ruiz, M. T.; Roman-Lopes, A.; Schreiber, M. R.; Schröder, A. C.; Smith, M.; Sodré, L., Jr.; Stephens, A. W.; Walton, N. A.; Zijlstra, A. A.; Tamura, M.; Tappert, C.; Thompson, M. A.; Vanzi, L.

    The VISTA Variables in the Via Lactea (VVV) is an ESO public near-IR variability survey that is scanning the Milky Way bulge and an adjacent section of the Galactic mid-plane. The survey will take 1929 hours of observations with the VISTA 4.1-m telescope during five years, covering a billion point sources across an area of 520 sqdeg, including 36 known globular clusters and more than 350 open clusters. The final product will be a deep IR atlas in five passbands (0.9 - 2.5 microns) and a catalogue of more than a million variable point sources.

  3. Two years at Meridiani Planum: Results from the opportunity rover

    USGS Publications Warehouse

    Squyres, S. W.; Knoll, A.H.; Arvidson, R. E.; Clark, B. C.; Grotzinger, J.P.; Jolliff, B.L.; McLennan, S.M.; Tosca, N.; Bell, J.F., III; Calvin, W.M.; Farrand, W. H.; Glotch, T.D.; Golombek, M.P.; Herkenhoff, K. E.; Johnson, J. R.; Klingelhofer, G.; McSween, H.Y.; Yen, A. S.

    2006-01-01

    The Mars Exploration Rover Opportunity has spent more than 2 years exploring Meridiani Planum, traveling ???8 kilometers and detecting features that reveal ancient environmental conditions. These include well-developed festoon (trough) cross-lamination formed in flowing liquid water, strata with smaller and more abundant hematite-rich concretions than those seen previously, possible relict "hopper crystals" that might reflect the formation of halite, thick weathering rinds on rock surfaces, resistant fracture fills, and networks of polygonal fractures likely caused by dehydration of sulfate salts. Chemical variations with depth show that the siliciclastic fraction of outcrop rock has undergone substantial chemical alteration from a precursor basaltic composition. Observations from microscopic to orbital scales indicate that ancient Meridiani once had abundant acidic groundwater, arid and oxidizing surface conditions, and occasional liquid flow on the surface.

  4. Results of Detailed Hydrologic Characterization Tests - Fiscal Year 2000

    SciTech Connect

    Spane, Frank A.; Thorne, Paul D.; Newcomer, Darrell R.

    2001-05-15

    This report provides the resluts of detailed hydrologic characterization tests conducted within eleven Hanford Site wells during fiscal year 2000. Detailed characterization tests performed included groundwater-flow characterization; barometric response evaluation; slug tests; single-well tracer tests; constant-rate pumping tests; and in-well, vertical flow tests. Hydraulic property estimates obtained from the detailed hydrologic tests include transmissivity; hydraulic conductivity; specific yield; effective porosity; in-well, lateral flow velocity; aquifer-flow velocity; vertical distribution of hydraulic conductivity (within the well-screen section); and in-well, verticla flow velocity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for four sites where detailed well testing was performed.

  5. DOE Radiological Calibrations Intercomparison Program: Results of fiscal year 1987

    SciTech Connect

    Cummings, F.M.; McDonald, J.C.

    1988-06-01

    This report presents the FY 1987 results of the radiological calibrations intercomparison program. The intercomparison operation is discussed, and the equipment is described, particularly the instrument set, the beta source set, and relevant calculations. Solutions to problems and improvements in the program are suggested, and conclusions are then introduced. 9 refs., 3 figs., 8 tabs.

  6. Results from the Australasian Vascular Surgical Audit: the inaugural year.

    PubMed

    Beiles, C Barry; Bourke, Bernie; Thomson, Ian

    2012-03-01

    The Australian and New Zealand Society for Vascular Surgery has incorporated a constitutional change to administer a self-funded compulsory vascular surgery audit since January 2010. This is a bi-national quality assurance activity that captures all procedures performed in both countries. Data is collected at two points in the clinical admission; at operation and at discharge and data entry is via the Internet. Security is stringent and confidentiality is guaranteed by Commonwealth privilege. Data privacy is maximized by encryption. The application is flexible and administered by a dedicated administrator with a help-desk facility. Reports are available to provide real-time feedback of user performance compared with the peer group data in key categories of arterial surgery. A structured hierarchy for data management has been established to assess four main categories of performance: mortality after aortic surgery, stroke and death after carotid surgery, patency and limb salvage after infrainguinal bypass and patency after arteriovenous access for haemodialysis. Data is analysed using risk-adjustment techniques and an algorithm for management of underperformance has been followed. Data validation has been performed. The outcomes in all categories have been of a high standard and correction of erroneous data in a single statistical outlier has negated underperformance. The audit has captured only 65% of the estimated procedures in Australia in the first year, but data quality is good. The feasibility of a complete compulsory bi-national audit has now been established and will be the benchmark for other craft groups in the current environment of accountability. PMID:22510117

  7. Results from two years of resistivity monitoring at Cerro Prieto

    SciTech Connect

    Wilt, M.J.; Goldstein, N.E.

    1981-01-01

    Dipole-dipole resistivity measurements for the combined purposes of reservoir delineation and resistivity monitoring were first made at Cerro Prieto in 1978 and have continued on an annual basis since then. Two 20 km long dipole-dipole lines with permanently emplaced electrodes at one kilometer spacings were established over the field area; one of these lines is remeasured annually. Resistivity measurements are taken using a 25 kW generator capable of up to 80A output and a microprocessor controlled signal averaging receiver; this high power-low noise system is capable of highly accurate measurements even at large transmitter-receiver separations. Standard error calculations for collected data indicate errors less than 5% for all points, but 95% confidence intervals show error limits about 2 to 4 times higher. Analysis of collected data indicate little change in the apparent resistivity of the upper 300 m over the field production zone and that in this section measurements are relatively insensitive to the annual rainfall cycle. Apparent resistivity increases were observed over the older producing zone at Cerro Prieto at depths of 1 km and greater. Large zones of decreasing apparent resistivity were observed flanking the zone of increases on both sides. The increase in apparent resistivity in the production region may be due to an increasing fraction of steam in the reservoir resulting from a production related decline in reservoir pressure. Alternatively the increases may be the result of fresh water influx from the Colorado River. The zone of declining resistivity flanking the area of increase may be due to the movement of saline waters into the reservoir region as a result of the pressure decline. Quantitative modeling of observed changes is impractical owing to the high uncertainty in estimating apparent resistivity changes and the nonuniqueness of models.

  8. Nimbus-7 global cloud climatology. II - First year results

    NASA Technical Reports Server (NTRS)

    Stowe, Larry L.; Yeh, H. Y. Michael; Wellemeyer, Charlie G.; Eck, Thomas F.; Kyle, H. Lee

    1989-01-01

    Results are presented on the analysis of the Nimbus-7 satellite data set obtained on regional and seasonal variations in global cloud cover. Four midseason months (April, July, and October 1979 and January 1980) were analyzed for the total cloud amount, the cloud amounts at high, middle, and low altitudes, the cirrus and deep convective clouds, and the cloud and clear-sky 11.5 micron-derived radiances; in addition, noon versus midnight cloud amounts were examined. The Nimbus-7 data are compared with three previously published cloud climatologies, and the differences among these data sets are discussed.

  9. Results from the first 4 years of pay for performance.

    PubMed

    DeVore, Susan D

    2010-01-01

    Some of the lessons hospitals that have participated in the Hospital Quality Incentive Demonstration project have learned include: the need to tie in quality-of-care initiatives to the organization's strategic plan and to incentive plans for all employees, from executives on down; the value in allowing hospital physicians to "own" quality improvement initiatives; the importance of making results of the initiative available to all staff; the benefit of creating best-practice teams to address improvements in specific clinical areas. PMID:20088476

  10. Results of Detailed Hydrologic Characterization Tests - Fiscal Year 1999

    SciTech Connect

    Spane, Frank A.; Thorne, Paul D.; Newcomer, Darrell R.

    2001-01-19

    This report provides the results of detailed hydrologic characterization tests conducted within newly constructed Hanford Site wells during FY 1999. Detailed characterization tests performed during FY 1999 included: groundwater flow characterization, barometric response evaluation, slug tests, single-well tracer tests, constant-rate pumping tests, and in-well vertical flow tests. Hydraulic property estimates obtained from the detailed hydrologic tests include: transmissivity, hydraulic conductivity, specific yield, effective porosity, in-well lateral flow velocity, aquifer flow velocity, vertical distribution of hydraulic conductivity (within the well-screen section) and in-well vertical flow velocity. In addition, local groundwater flow characteristics (i.e., hydraulic gradient and flow direction) were determined for four sites where detailed well testing was performed.

  11. SMART-1 SPEDE: Results and Legacy after 10 Years

    NASA Astrophysics Data System (ADS)

    Schmidt, Walter; Mälkki, Anssi

    2014-05-01

    sensor area treatment was optimized for SPEDE and used in all subsequent Langmuir probe designs of IRF/Uppsala. The algorithm implemented inside the SPEDE on-board software to analyze the plasma wave measurements was optimized during the SMART-1 mission and later uplinked to the ESA Rosetta spacecraft lander Philae, where it is now used to analyze and compress the data of the permittivity probe, also used as a plasma wave monitor with W.Schmidt as PI. The experience gained from the FPGA-implementation of a self-developed processor was later used in preparation of ESA's ExoMars 2016 pressure sensor controller and the Swedish plasma instrument LINA for a Russian Lunar mission as well as for the ESA JUICE mission to the Jupiter system. Reference: [1] Mälkki, A., Schmidt, W., Laakso, H., Grard, R., Escoubet, C.P., Wahlund, J.-E., Blomberg, L., Marklund, G. and Johlander, B., 2003: The SPEDE experiment on SMART-1: Instrument, mission, and science objectives. Geophysical Research Abstracts, Vol 5., 10004, 2003. [2] Mälkki, A., Schmidt, W., Laakso, H., Johlander, B., Wahlund, J.E., Blomberg, L., Marklund, G., Grard, R., Escoubet, C.P. and Lebreton, J.P., 2004: First results from SMART-1/ SPEDE plasma experiment. European Geophysical Union EGU-2004, EGU04-A-02543. Invited oral presentation [3] Mälkki, A., Schmidt, W., Genzer, M., Merikallio, S., Laakso, H., Gonzales del Amo, J., Estublier, D., Gengembre, E., Hilgers, A., Capacci, M., Koppel, C. and Tajmar, M., 2005: Spacecraft-plasma interaction analysis using data from SPEDE on SMART-1. 10th Scientific Assembly of IAGA, Toulouse, France, July 2005, paper IAGA2005-A-01401 [4] Mälkki, A., Schmidt, W., Kallio, E. and Merikallio, S., 2006: Interaction of Solar Wind With the Moon: Results From Hybrid Modeling and the SPEDE Instrument on SMART-1. Geophysical Research Abstracts, Vol. 8, 07632, 2006 [5] M.Backrud, 2007: Evaluation of the SPEDE instrument on SMART-1, Royal Institute of Technology (KTH) Report - TRITA-EE 2007:023

  12. Assessing Value-Added in the First Year of Schooling: Some Results and Methodological Considerations

    ERIC Educational Resources Information Center

    Sharp, Stephen

    2006-01-01

    This article reports data from children aged about 5 years in their 1st year of schooling. Scores on tests of both literacy and numeracy at the start and end of the year were used to derive value-added measures of progress using both residual gain analysis and multilevel (ML) modelling. Results indicated that the school was more effective in…

  13. Open Surgical Treatment for Femoroacetabular Impingement in Patients over Thirty Years: Two Years Follow-up Results

    PubMed Central

    2015-01-01

    Purpose We report short term results of open surgical treatment for symptomatic femoroacetabular impingement (FAI) in patients over the age of 30 years. Materials and Methods Between May 2011 and June 2012, thirteen FAI hips (11 patients) with hip pain persisting longer than 6 months were treated by either surgical hip dislocation (SHD) or anterior mini-open. They were followed up for longer than 2 years. The 11 patients included 7 females and 4 males with a mean age of 45 (range, 33-60) years. They were clinically evaluated for modified Harris hip score (MHHS) and University of California at Los Angeles (UCLA) activity level. Their lateral center-edge angle, acetabular index, and alpha angle were measured and compared. Results Acetabuloplasties were performed for seven cases. Femoral osteochondroplasty was performed for all thirteen cases. At minimum follow-up of two year (range, 24-29 months), all patients had substantial relief in preoperative pain with improvement in range of motion. The median MHHS was significantly (P<0.05) improved from 61 points preoperatively to 87 points at the last follow-up. The median UCLA activity level was 7 (range, 5-8) at last follow-up. Radiological indices improved. Two cases showed mild residual pain attributable to adhesion between capsule and reshaped femoral head-neck area. Conclusion Open surgical treatment of FAI was a reliable and effective treatment method in symptomatic FAIs for patients over the age of 30 years without advanced arthritic change of hip joint at short term follow-up.

  14. Fifteen Years of Collaborative Innovation and Achievement: NASA Nebraska Space Grant Consortium 15-Year Program Performance and Results Report

    NASA Technical Reports Server (NTRS)

    Schaaf, Michaela M.; Bowen, Brent D.; Fink, Mary M.; Nickerson, Jocelyn S.; Avery, Shelly; Carstenson, Larry; Dugan, James; Farritor, Shane; Joyce, James; Rebrovich, Barb

    2003-01-01

    Condensing five years of significant work into a brief narrative fitting PPR requirements gave the affiliates of the Nebraska Space Grant a valuable chance for reflection. Achievements of Space Grant in Nebraska were judiciously chosen for this document that best illustrate the resultant synergism of this consortium, keeping in mind that these examples are only a representation of greater activity throughout the state. Following are highlights of many of the finer and personal achievements for Nebraska Space Grant. The Consortium welcomes inquiries to elaborate on any of these accomplishments.

  15. Fifteen Years of Collaborative Innovation and Achievement: NASA Nebraska Space Grant Consortium 15-Year Program Performance and Results Report

    NASA Technical Reports Server (NTRS)

    Schaaf, Michaela M. (Editor); Bowen, Brent D.; Fink, Mary M.; Nickerson, Jocelyn S.; Avery Shelly; Calamaio, Caprice; Carstenson, Larry; Dugan, James; Farr, Lynne; Farritor, Shane

    2003-01-01

    This 15-year evaluation serves as a summary document highlighting the numerous and complete successes of the Nebraska Space Grant Program. Innovation has been highlighted through significant new endeavors during this 5-year period, such as placement of students and faculty at NASA Centers and the expansion of NSGC Native American Outreach Programs. While the last national program evaluation resulted in Nebraska s ranking as the top Capability Enhancement Consortium, and 5th best overall, Nebraska felt there was room for significant growth and development. This has been validated through the recent competitive attainment of Designated Grant status and has allowed for the exploration of new initiatives, as well as the expansion of already successful programs. A comprehensive strategic planning effort has involved all Nebraska representative entities and has guided Nebraska Space Grant through the evaluation period, providing a basis for continual advancement. Nebraska rigorously employs evaluation techniques to ensure that stated outcomes and metrics are achieved and that weaknesses are identified and corrected. With this coordinated approach, Nebraska expects that the next 5 years will yield new opportunities for significant achievement. Nebraska Space Grant will embrace new national endeavors, including the integration of Pender Public Schools -Nebraska s NASA Explorer School, geospatial initiatives, and the National Student Satellite Program.

  16. A-Level Results in Comprehensive Schools: The COMBSE Project, Year 1.

    ERIC Educational Resources Information Center

    Fitz-Gibbon, Carol T.

    1985-01-01

    Results of the first year of the ongoing Confidential, Measurement-Based, Self-Evaluation Project that examines variables related to A-level English and Mathematics achievement in 10 comprehensive schools in the United Kingdom are presented. A-level results were found to be strongly predicted by teacher assessments and by prior O-level achievement…

  17. High Remission Rate of Chronic Immune Thrombocytopenia in Children: Result of 20-Year Follow-Up

    PubMed Central

    Kim, Chae Young; Lee, Eun Hye

    2016-01-01

    Purpose This study examined the outcomes of children with chronic immune thrombocytopenia (ITP). Materials and Methods We retrospectively analyzed the medical records of all patients diagnosed with ITP from January 1992 to December 2011 at our institution. Results A total of 128 patients (64%) satisfied the criteria for newly diagnosed ITP, 31 (15%) for persistent ITP, and 41 (21%) for chronic ITP. The median age at diagnosis was 4.5 years (range, 1 month to 18 years). The median platelet count at diagnosis was 32×109/L. A comparison of the initial treatment data from 2001 to 2011 with those from 1992 to 2000 showed that the number of bone marrow examinations decreased, whereas observation increased. Chronic ITP presented at an older age than newly diagnosed and persistent ITP (6.6 years vs. 3.8 years vs. 4.1 years, respectively); however, the difference did not reach statistical significance (p=0.17). The probability of complete remission of chronic ITP was 50% and 76% at 2 and 5 years after diagnosis, respectively. Patients aged <1 year at diagnosis had a significantly better prognosis than did older patients (hazard ratio, 3.86; p=0.02). Conclusion Children with chronic ITP showed a high remission rate after long-term follow-up. This study suggests that invasive treatments such as splenectomy in children with chronic ITP can be delayed for 4 to 5 years if thrombocytopenia and therapeutic medication do not affect the quality of life. PMID:26632392

  18. Cementless porous-coated total knee arthroplasty: 10-year results in a consecutive series.

    PubMed

    Schrøder, H M; Berthelsen, A; Hassani, G; Hansen, E B; Solgaard, S

    2001-08-01

    We report the results of 114 AGC 2000 porous-coated, cementless total knee arthroplasties (TKA) performed consecutively in 102 patients during the period 1984-1986. After 10 years, 58 TKAs in 52 patients were evaluated with patient assessment, Hospital for Special Surgery knee score, weight-bearing radiographs done under fluoroscopic control, and survivorship analysis. All dropouts within the first 9 years were patients dying with a functioning TKA except 1 revision secondary to a supracondylar fracture after 8.5 years. Of the patients, 53 (92%) were satisfied or very satisfied with their TKA, and 55 (95%) of the knees were rated good or excellent. There was no pain in 53 knees, and the median knee flexion was 110 degrees. Six radiolucencies >1 mm were found beneath parts of the tibial component, and 5 radiolucencies were seen beneath the femoral component. None had progressed compared with the 5-year follow-up, and in all cases trabeculae could be seen reaching the prosthetic component. No migrations had occurred since the 5-year follow-up. No obvious joint space reduction was seen. Osteolysis presenting as an isolated cyst was found in 1 knee in the lateral tibial condyle and was not progressive. Two tibial components had been revised because of aseptic loosening and 1 because of septic loosening, all within the first 3 years. No femoral or patellar components were revised. The cumulative prosthesis survival rate after 10 to 11 years was 97%. When pain and radiographic loosening also were considered, the success rate was 87%. Cementless insertion of a nonmodular, porous-coated TKA resulted in a long-term durable bone-prosthesis interface. The flat-on-flat articulation did not result in catastrophic polyethylene wear or osteolysis within the first 10 years. PMID:11503114

  19. Total knee arthroplasty using cementless keels and cemented tibial trays: 10-year results

    PubMed Central

    Kolisek, Frank R.; Mont, Michael A.; Seyler, Thorsten M.; Marker, David R.; Jessup, Nenette M.; Siddiqui, Junaed A.; Monesmith, Eric

    2008-01-01

    The problem of early mechanical stability of cemented and cementless keels of the tibial component in total knee arthroplasty (TKA) is controversial. The purpose of this study was to assess clinical and radiographic outcomes of a cohort of 51 TKAs using a cemented platform with cementless keel fixation. At a mean follow-up of 10.4 years (range, 7 to 14 years), the mean Knee Society Score (KSS) was 93 points (range, 59 to 100 points), and the mean functional score was 73 points (range, 0 to 100 points). Only one patient demonstrated progressive tibial radiolucencies at 13.1 years follow-up, which resolved with a revision with an exchange of components. The results of this study suggest that a proximally cemented tibial tray with a press-fit keel TKA provides excellent mean 10-year outcomes. PMID:18185931

  20. Propellant/material compatibility program and results: Ten-year milestones

    NASA Technical Reports Server (NTRS)

    Moran, C.; Bjorkland, R.

    1982-01-01

    The analyses and results of a test program to establish the effects of long term (10 years or more) contact of materials with earth-storable propellants for the purpose of designing chemical propulsion system components which are used for current as well as future planetary spacecraft are described. The period from the publication of JPL TM 33-779 IN 1976 through the testing accomplished in 1981 is covered. The following propellants are reported herein: hydrazine, monomethylhydrazine and nitrogen tetroxide. Materials included the following: aluminum alloys, corrosion resistant steels and a titanium alloy. The results of the testing of more than 80 specimens are included. Material ratings relative to the ten year milepost were assigned. Some evidence of propellant decomposition was found. Titanium is rated as acceptable for ten year applications. Aluminum and stainless steel alloys are also rated as acceptable with few restrictions.

  1. Nonsurgical Transurethral Radiofrequency Collagen Denaturation: Results at Three Years after Treatment

    PubMed Central

    Elser, Denise M.; Mitchell, Gretchen K.; Miklos, John R.; Nickell, Kevin G.; Cline, Kevin; Winkler, Harvey; Wells, W. Glen

    2011-01-01

    Objective. To assess treatment efficacy and quality of life in women with stress urinary incontinence 3 years after treatment with nonsurgical transurethral radiofrequency collagen denaturation. Methods. This prospective study included 139 women with stress urinary incontinence due to bladder outlet hypermobility. Radiofrequency collagen denaturation was performed using local anesthesia in an office setting. Assessments included incontinence quality of life (I-QOL) and urogenital distress inventory (UDI-6) instruments. Results. In total, 139 women were enrolled and 136 women were treated (mean age, 47 years). At 36 months, intent-to-treat analysis (n = 139) revealed significant improvements in quality of life. Mean I-QOL score improved 17 points from baseline (P = .0004), while mean UDI-6 score improved (decreased) 19 points (P = .0005). Conclusions. Transurethral collagen denaturation is a low-risk, office-based procedure that results in durable quality-of-life improvements in a significant proportion of women for as long as 3 years. PMID:22190917

  2. First-Year Results of an Obesity Prevention Program at The Dow Chemical Company

    PubMed Central

    Goetzel, Ron Z.; Baker, Kristin M.; Short, Meghan E.; Pei, Xiaofei; Ozminkowski, Ronald J.; Wang, Shaohung; Bowen, Jennie D.; Roemer, Enid C.; Craun, Beth A.; Tully, Karen J.; Baase, Catherine M.

    2010-01-01

    Objective To examine first-year results from a workplace environmental obesity prevention program at The Dow Chemical Company. Methods A quasi-experimental cohort study was conducted among employees at nine treatment worksites (n=8,013) who received environmental weight management interventions and three control worksites (n=2,269). Changes in employees’ weight, body mass index (BMI), and other health risks were examined using chi-square and t-tests. Results After one year, a modest treatment effect was observed for weight and BMI largely because the control group subjects gained weight; however, no effect was observed for overweight and obesity prevalence. Other risk factors (tobacco use, high blood pressure, and systolic and diastolic blood pressure values) decreased significantly, although blood glucose (high risk prevalence and values) increased. Conclusions Environmental changes to the workplace can achieve modest improvements in employees’ health risks, including weight and BMI measures, in one year. PMID:19209033

  3. Research Results: Mobility of BC Transfer Students. Fall 2007 to Calendar Year 2008

    ERIC Educational Resources Information Center

    Heslop, Joanne

    2009-01-01

    This newsletter highlights research results on the Mobility of Transfer Students (MTS), a branch of research conducted under the auspices of the Student Transitions Project (STP). In this annual study, students enrolled in the Fall of 2007 in BC colleges, university colleges, and institutes were followed into calendar year 2008 to identify those…

  4. Two- and Three-Year Achievement Results from the Memphis Restructuring Initiative.

    ERIC Educational Resources Information Center

    Ross, Steven M.; Sanders, William L.; Wright, S. Paul; Stringfield, Sam; Wang, L. Weiping; Alberg, Marty

    2001-01-01

    Presents the results of a study of student achievement, using a value-added testing technique, after 3 years of Memphis Restructuring Initiative. Findings show positive achievement gains in reform schools compared to demographically similar control schools, though strength of gains varied by type of reform and community poverty levels. (Contains…

  5. Incredible Years Program Tailored to Parents of Preschoolers with Autism: Pilot Results

    ERIC Educational Resources Information Center

    Dababnah, Sarah; Parish, Susan L.

    2016-01-01

    Objective: This article reports on the acceptability and results from an evaluation of an empirically supported practice, The Incredible Years, tailored to parents of children with autism spectrum disorder (ASD). Methods: Two groups of parents (N = 17) participated in a mixed methods test with no comparison group of the 15-week intervention. Data…

  6. School Social Work Case Characteristics, Services, and Dispositions: Year One Results

    ERIC Educational Resources Information Center

    Jonson-Reid, Melissa; Kontak, Dot; Citerman, Barbara; Essma, Angie; Fezzi, Nancy

    2004-01-01

    This article describes the results from the first year of a longitudinal study of a school social work caseload in a large midwestern school district. The purpose of the investigation was to examine the relationship among case characteristics, types of services provided, and case dispositions. Data were collected using a management information…

  7. Learning Benefits of Self-Controlled Knowledge of Results in 10-Year-Old Children

    ERIC Educational Resources Information Center

    Chiviacowsky, Suzete; Wulf, Gabriele; Laroque de Medeiros, Franklin; Kaefer, Angelica; Tani, Go

    2008-01-01

    The purpose of the present study was to examine whether the learning benefits of self-controlled knowledge of results (KR) would generalize to children. Specifically, the authors chose 10-year-old children representative of late childhood. The authors used a task that required the children to toss beanbags at a target. One group received KR…

  8. The results of photorefractive keratectomy with Mitomycin-C in myopia correction after 5 years

    PubMed Central

    Hashemi, Masih; Amiri, Mohammad Aghazadeh; Tabatabaee, Mehdi; Ayatollahi, Ali

    2016-01-01

    Objective: To evaluate the results of photorefractive keratectomy (PRK) with mitomycin C in myopia correction after five years. Methods: This is a cross sectional study which included 145 eyes of 74 patients in 18 to 51 years age group that were undergoing Photorefractive keratectomy with mitomycin C using Allegretto Wave Eye-Q 400-Hz excimer laser platform in Markazi Eye Center, Tehran, Iran. All the surgical procedures were performed by the same surgeon. After five years follow-up evaluation including BCVA, UCVA, Refractive error measurement and external eye examination was performed. Results: The mean diopter of spherical equivalent before surgery was -3.40±1.73. The following findings were obtained after 5 years follow up visit: The mean spherical equivalent value: -0.08±0.40, the mean: Log MARUCVA: 0.02±0.07, the mean Log MAR BCVA: 0.00±0.04. Conclusion: PRK is an effective, safe and predictable method used to correct myopia. The wave front-optimized algorithm of the Allegretto Wave Eye-Q 400-Hz excimer laser platform demonstrated good refractive and visual results. Presence of variables such as gender, age and astigmatism before operation have no significant impact on the result of this operation. PMID:27022380

  9. After One Year, Mixed Results from Push for Neighborhood Schools. Research Brief. Volume 90, Number 4

    ERIC Educational Resources Information Center

    Public Policy Forum, 2002

    2002-01-01

    One school year after implementation of the Neighborhood Schools Initiative (NS), more Milwaukee Public School (MPS) district schools enroll more neighborhood students, although the increase in neighborhood enrollment is not the result of capacity-building; fewer schools have the capacity to enroll all their neighborhood students than two years…

  10. [Neuro-occlusal rehabilitation and selective grinding: results after 1 year].

    PubMed

    Martin, E

    2000-01-01

    The aim of this work is to illustrate the results, one year after selective grindings have been used in "Neuro-Occlusal Rehabilitation" (N.O.R.). These selective grindings have been described by Pr Planas and are used to free mandibular lateral movements, in order to facilitate correct development of the stomatognathic system. PMID:10838864

  11. Organic methods for control of pecan weevil: Results of the first year's field trials

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Integrated organic tactics for control of pecan weevil were investigated in large field plot tests. The experiment was conducted at two locations: USDA-ARS Research Lab in Byron, GA and Cleveland farms in Fort Valley, GA. Results from the first year field trials indicated that organic tactics for ...

  12. DEMONSTRATION OF WELLMAN-LORD/ALLIED CHEMICAL FGD TECHNOLOGY: DEMONSTRATION TEST SECOND YEAR RESULTS

    EPA Science Inventory

    The report gives results of an evaluation of the performance (over a 2-year period) of a full-scale flue gas desulfurization (FGD) unit to demonstrate the Wellman-Lord/Allied Chemical process. The process is regenerable, employing sodium sulfite wet scrubbing, thermal regeneratio...

  13. Utilising Year Three NAPLAN Results to Improve Queensland Teachers' Mathematical Pedagogical Content Knowledge

    ERIC Educational Resources Information Center

    van Klinken, Eduarda

    2010-01-01

    Poor results in Queensland Year Three NAPLAN Numeracy tests have provided a focus to critically review the classroom practices of lower primary mathematics teachers. This paper outlines how pedagogical content knowledge can be strengthened by emphasising conceptual understanding, by utilising dynamic classroom discourse, by an awareness of…

  14. The five-year radiological results of the uncemented Oxford medial compartment knee arthroplasty.

    PubMed

    Hooper, N; Snell, D; Hooper, G; Maxwell, R; Frampton, C

    2015-10-01

    This study reports on the first 150 consecutive Oxford cementless unicompartmental knee arthroplasties (UKA) performed in an independent centre (126 patients). All eligible patients had functional scores (Oxford knee score and high activity arthroplasty score) recorded pre-operatively and at two- and five-years of follow-up. Fluoroscopically aligned radiographs were taken at five years and analysed for any evidence of radiolucent lines (RLLs), subsidence or loosening. The mean age of the cohort was 63.6 years (39 to 86) with 81 (53.1%) males. Excellent functional scores were maintained at five years and there were no progressive RLLs demonstrated on radiographs. Two patients underwent revision to a total knee arthroplasty giving a revision rate of 0.23/100 (95% confidence interval 0.03 to 0.84) component years with overall component survivorship of 98.7% at five years. There were a further four patients who underwent further surgery on the same knee, two underwent bearing exchanges for dislocation and two underwent lateral UKAs for disease progression. This was a marked improvement from other UKAs reported in New Zealand Joint Registry data and supports the designing centre's early results. PMID:26430010

  15. Ten years of photonics education at the college level in Ontario: results and by-products

    NASA Astrophysics Data System (ADS)

    Nantel, Marc

    2010-08-01

    In 2000, there was no way for an Ontario student to obtain a credential in optics, laser or photonics without going through graduate school. This was in, arguably, the world-leading jurisdiction in photonics-enabled telecommunications industry. To alleviate this problem and supply the job market with highly-qualified people in the field of optics and photonics, the Ontario Centres of Excellence - then as Photonics Research Ontario - partnered with Algonquin College (Ottawa) and Niagara College (Welland) to establish over the past decade a suite of programs: a 1-year Certificate in Advanced Lasers, a 2-year Diploma for Photonics Engineering Technician, a 3-year Diploma for Photonics Engineering Technologists and a 4-year Bachelor of Applied Technology - Photonics. Much has been learnt along the way - the crucial need for industrial partner and government support, for example - and many course corrections had to be made (telecom bust, anyone?). The author will share the results of this 10-year journey so far, the lessons learnt, and a view to the next ten years for these programs and photonics education in Ontario in general.

  16. Changes in Weight over the School Year and Summer Vacation: Results of a 5-Year Longitudinal Study

    ERIC Educational Resources Information Center

    Moreno, Jennette P.; Johnston, Craig A.; Woehler, Deborah

    2013-01-01

    Background: Evidence suggests that children gain more weight during the summer months compared with the school year. To examine the impact of the school and summer environment on children's weight further, we conducted a 5-year longitudinal study examining changes in standardized BMI (zBMI) of students entering kindergarten. Methods: Heights…

  17. Changes in weight over the school year and summer vacation: Results of a 5-year longitudinal study

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Evidence suggests that children gain more weight during the summer months compared with the school year. In order to further examine the impact of the school and summer environment on children's weight, we conducted a 5-year longitudinal study examining changes in standardized BMI (zBMI) of students...

  18. Changes in weight over the school year and summer vacation: Results of a 5-year longitudinal study

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Some evidence suggests that children have relatively higher increases in weight during the summer months compared to the school year. In order to further examine the impact of the school and summer environment on children's weight, we conducted a 5-year longitudinal study examining changes in standa...

  19. [Evaluation of a 20 years' experience of colo-anal anastomoses. Indications, results and pitfalls].

    PubMed

    Hautefeuille, P; Saab, M; Valleur, P

    1991-01-01

    Seventy nine anastomoses were performed over a 20 year period. Indications included 68 rectal adenocarcinomas and 11 benign lesions. There was no operative mortality. Anastomotic leak was the main cause of morbidity: 12 clinical (15%) and 4 radiological leaks. The 5-year actuarial disease-free survival was 70%, 7 local recurrences (10%) were observed; 6 were Dukes C and 1 Dukes B. Functional results were assessed in 61 patients. They were considered to be excellent in 35 (57%), good in 24 (39%) and bad in 2 (4%). Six failures were noted: 3 technical, 1 oncologic and 2 functional. Pitfalls of coloanal anastomosis are discussed. PMID:2064292

  20. Results.

    ERIC Educational Resources Information Center

    Zemsky, Robert; Shaman, Susan; Shapiro, Daniel B.

    2001-01-01

    Describes the Collegiate Results Instrument (CRI), which measures a range of collegiate outcomes for alumni 6 years after graduation. The CRI was designed to target alumni from institutions across market segments and assess their values, abilities, work skills, occupations, and pursuit of lifelong learning. (EV)

  1. Unilateral lower limb lymphedema resulting from a heart surgery performed 50 years prior

    PubMed Central

    Onoda, Satoshi; Miura, Yuki; Sugiyama, Narushi

    2015-01-01

    Introduction Lymphedema is classified into two main types: secondary lymphedema accompanied by lymph node excision surgery or radiotherapy; and idiopathic lymphedema. Here we experienced a very rare case of lymphatic edema resulting from cardiac surgery that the patient underwent 50 years previously. Presentation of case A 62-year-old woman experienced progressive unilateral lower leg lymphedema for recent years. After undergoing cardiac surgery at another hospital at the age of 12 years, she gradually developed left lower leg edema. The cause of the edema was unclear and it remained untreated. Her edema symptoms gradually worsened in recent years, so she consulted the plastic surgery division of our hospital. Discusssion Perhaps the lymphatic structures of affected individuals differ prior to disease onset. If the mechanism of lymphatic edema outbreak is elucidated, patients needing conservative and surgical therapy might be more easily identified. Knowing the outbreak mechanism of lymphatic edema would definitely ease the investigation of an unconventional case like this one. Conservative treatments for lymphedema, such as self-massage and compression therapy using garments, were immediately started. With these treatments, the leg volume and edema symptoms reduced. Conclusion The research on the cause of this case may be important step for elucidating the source of secondary lymphatic edema. PMID:26719996

  2. Acute Vs Delayed ACL Reconstruction. Early Differences and Preliminary Two Year Results

    PubMed Central

    Eriksson, Karl; Barenius, Björn

    2016-01-01

    Objectives: Historically acute ACL reconstruction has been avoided due to reports of early rehabilitation problems with stiffness. Are these reports still valid today with modern arthroscopic techniques? Methods: 70 patients with a high recreational activity level (Tegner ≥6) who presented with a acute ACL injury were randomized to an acute reconstruction within 8 days from the injury or delayed reconstruction after 6-10 weeks. Four surgeons performed the ACL reconstructions with quadrupled semitendinosus tendon grafts and endobutton and metallic interference screw fixation. The rehabilitation training was performed at the same physiotherapy center for all patients. The follow up at 6 and 24 months included ROM, Lachman, Rolimeter, pivot shift, one leg hop, IKDC, KOOS, Lysholm and Tegner activity level. Results: There were no differences between the groups in ROM, IKDC, activity level or laxity at 6 months. Four patients had a combined extension and flexion deficit of more than 15 degrees, two from each group. In the acute group 79% had an objective IKDC grade A or B compared with 73% in the delayed group. The one leg hop index above 90% was found in 50% in the acute group and 24% in the delayed group (p=0.04). Functional data for the 2-year follow up are not available at the time of abstract writing. The median activity level according to Tegner was restored to pre-injury levels in both groups after one year, and was stationary at 2 years. The visual analogue scale (VAS) response to the question “How is your knee working on a scale from 0-100? (100 = best)” revealed 81 in the acute and 71 in the delayed group (p=0.1). To the question “How does your knee affect your activity level on a scale from 0-100? (100 = no affection)” the mean score was 75 in the acute group and 67 in the delayed group (p=0.3). At one and two years the KOOS was statistically similar between the groups but with slightly higher subscale “Sport and recreation” scores, 85 in the

  3. Video game addiction and college performance among males: results from a 1 year longitudinal study.

    PubMed

    Schmitt, Zachary L; Livingston, Michael G

    2015-01-01

    This study explored the pattern of video game usage and video game addiction among male college students and examined how video game addiction was related to expectations of college engagement, college grade point average (GPA), and on-campus drug and alcohol violations. Participants were 477 male, first year students at a liberal arts college. In the week before the start of classes, participants were given two surveys: one of expected college engagement, and the second of video game usage, including a measure of video game addiction. Results suggested that video game addiction is (a) negatively correlated with expected college engagement, (b) negatively correlated with college GPA, even when controlling for high school GPA, and (c) negatively correlated with drug and alcohol violations that occurred during the first year in college. Results are discussed in terms of implications for male students' engagement and success in college, and in terms of the construct validity of video game addiction. PMID:25584728

  4. Household hazardous waste collection results, state fiscal years 1996, 1997, 1998

    SciTech Connect

    Rion, D.

    1998-12-01

    Some household products are potentially dangerous to living things and the environment when disposed of improperly. The Illinois Environmental Protection Agency (IEPA) has designed a program to deal with such problem wastes. Utilizing funds from the Solid Waste Management Fund, the Agency sponsored 90 collections during the state fiscal years 1996, 1997, and 1998. The report details the need for household hazardous waste collections in Illinois and summarizes the results of the projects.

  5. Evaluation of the management of Hr-HPV+/PapTest- women: results at 1-year recall

    PubMed Central

    Chiappetta, Caterina; Puggioni, Chiara; Lendaro, Eugenio; Cacciotti, Jessica; Zaralli, Roberto; Migliore, Giovanna; Bellardini, Paola; Petrozza, Vincenzo; Della Rocca, Carlo; Di Cristofano, Claudio

    2015-01-01

    With cervical cancer screening the choice of 1-year as a period of follow-up in positive high-risk HPV women without cytological lesions is still under discussion. We evaluated the management of these women and the role of HPV genotyping test. We did a cervical cancer screening study of women aged 35-64 with primary high-risk HPV test. Women positive for high-risk HPV with negative cytology were followed-up after 1 year. In this study we selected women with high-risk HPV+/PapTest- resulted high-risk HPV+ at recall and performed the PapTest and HPV genotyping test. The detection rate of squamous high grade (CIN2+) relative to the total screened cohort was 2.1‰, and it was 0.2‰ at the 1-year recall. The colposcopy performed in women referred at the 1-year recall accounted for 48.8% of the total (baseline + 1-year recall), and 84.3% of these women had no cytological lesions. The most frequent hr-HPV genotype detected was HPV16 and 66.7% of co-infections were due to HPV16 and HPV18. 54.5% of women presented a persistent infection at 1-year recall with the same HPV subtype, 50% of persistent infections was due to HPV16 and 16.7% of these were determined to be CIN2+ histological lesions. Our data show that it may be useful to extend the period of follow-up for women hr-HPV+/PapTest- so as to reduce the number of unnecessary colposcopies due to the transitory infections and that the genotyping test could help to identify the persistent infections in which HPV16 is involved. PMID:26884886

  6. Results From a Transitional-Year Program Director Survey: Identifying Crucial Issues and Concerns

    PubMed Central

    Craig, Steven R.; Smith, Hayden L.; Short, Matthew W.

    2012-01-01

    Background Transitional Year (TY) programs meet an important need by preparing residents for specialties that accept individuals after an initial preparatory year. To our knowledge, no surveys to date have been conducted to identify attributes of TY programs and concerns of TY program directors. Purpose The purpose of this study was to review TY program characteristics and identify critical issues and concerns of TY program directors (TYPDs). Methods A web-based, 22-question survey was sent to all 114 TYPDs of programs accredited by the Accreditation Council for Graduate Medical Education between January and April 2011. The survey included open-formatted and closed-formatted questions addressing program and institution demographics, program director time, administrative support, satisfaction, and future plans. Results The survey response rate was 86%. The median age of TY programs was 28 years, with few new programs. More than 80% of TY programs were conducted at community hospitals and university-affiliated community hospitals. Of the responding TYPDs, 17% had served less than 2 years, and 32% had served 10 years or more. Common sponsoring TY programs included internal medicine (88%), general surgery (42%), family medicine (25%), emergency medicine (24%), and pediatrics (18%). Overall, TYPDs were satisfied with their positions. They expressed concerns about inadequate time to complete duties, salary support, and administrative duties assigned to program coordinators. Forty-nine percent of TYPDs reported they planned to leave the position within the next 5 years. Conclusions Our survey provides useful information to assist institutions and the graduate medical education community in meeting the needs of TYPDs and strengthening TY programs. PMID:23451303

  7. 10 years results of an uncemented metaphyseal fit modular stem in elderly patients

    PubMed Central

    De la Torre, Basilio J; Chaparro, Manuel; Romanillos, Juan O; Zarzoso, Sara; Mosquera, Margarita; Rodriguez, Gil

    2011-01-01

    Background: There are concerns with regard to the femoral fixation in cementless total hip arthroplasty in elderly patients. We report a retrospective analysis of clinical and radiological results of uncemented metaphyseal fit modular stem in elderly patients irrespective of anatomic characterstics of proximal femur. Materials and Methods: This study reviews the outcomes of 60 primary hip replacements using a metaphyseal fit modular stem (third-generation Omniflex stem) conducted in 54 patients, of age 75 years or older. After a mean follow-up of 10,4 years, complete clinical and radiographic records were available for 52 hips of 48 patients. The patients were evaluated by Harris Hip Score (HHS). Results: There was a significantly improved pain score and Harris Hip Score (41,6 to 83,2). Six stems (11.53%) were revised: four because of periprosthetic fracture; one stem was well fixed, but presented a large osteolytic lesion in the metaphyseal area and the last stem was revised because of aseptic loosening. Stem survival taking aseptic loosening as the end-point was 98%. Bone atrophy in the proximal femur caused by stress shielding was observed in 39 stems (75%), but there was no case of subtrochanteric stress shielding. Moreover, atrophy appeared within two years postoperatively, with no extension thereafter. Conclusions: We achieved good clinical and radiographic results by uncemented metaphyseal fit femoral stem regardless of patient's age and femoral canal type. PMID:21772630

  8. Results of Medium Seventeen Years' Follow-Up after Laparoscopic Choledochotomy for Ductal Stones

    PubMed Central

    Quaresima, Silvia; Balla, Andrea; Guerrieri, Mario; Campagnacci, Roberto; D'Ambrosio, Giancarlo; Lezoche, Emanuele; Paganini, Alessandro M.

    2016-01-01

    Introduction. In a previously published article the authors reported the long-term follow-up results in 138 consecutive patients with gallstones and common bile duct (CBD) stones who underwent laparoscopic transverse choledochotomy (TC) with T-tube biliary drainage and laparoscopic cholecystectomy (LC). Aim of this study is to evaluate the results at up to 23 years of follow-up in the same series. Methods. One hundred twenty-one patients are the object of the present study. Patients were evaluated by clinical visit, blood assay, and abdominal ultrasound. Symptomatic patients underwent cholangio-MRI, followed by endoscopic retrograde cholangiopancreatography (ERCP) as required. Results. Out of 121 patients, 61 elderly patients died from unrelated causes. Fourteen patients were lost to follow-up. In the 46 remaining patients, ductal stone recurrence occurred in one case (2,1%) successfully managed by ERCP with endoscopic sphincterotomy. At a mean follow-up of 17.1 years no other patients showed signs of bile stasis and no patient showed any imaging evidence of CBD stricture at the site of choledochotomy. Conclusions. Laparoscopic transverse choledochotomy with routine T-tube biliary drainage during LC has proven to be safe and effective at up to 23 years of follow-up, with no evidence of CBD stricture when the procedure is performed with a correct technique. PMID:26880900

  9. Ten-year results after cementless THA with a sandwich-type alumina ceramic bearing.

    PubMed

    Park, Youn-Soo; Park, Se-Jun; Lim, Seung-Jae

    2010-11-01

    We analyzed the long-term results of a single-surgeon series of 102 cementless total hip arthroplasties (THAs) performed using a sandwich-type alumina ceramic bearing. The prostheses involved a porous-coated acetabular socket, a polyethylene-alumina composite liner, a 28-mm alumina head, and a grit-blasted titanium-alloy stem. Mean patient age at the time of THA was 39 years (range, 18-66 years), and 76% of the patients were younger than 50 years. All procedures were performed with use of the same surgical technique and the same implant at a single center. Mean follow-up was 115 months (range, 84-133 months). When failure was defined as revision of either the acetabular or the femoral component for any reason, Kaplan-Meier survival probability at 10 years was 95.3% (95% confidence interval, 89.5%-100%). Mean Harris Hip Score improved from 47 points (range, 16-70 points) preoperatively to 95 points (range, 85-100 points) at final follow-up. No radiographically detectable osteolysis around the acetabular or femoral component was observed in any hip. No patient reported squeaking in the operated hip. During the follow-up period, 3 hips (3%) required revision surgery; 2 underwent acetabular revision because of a ceramic liner fracture and 1 underwent revision for early loosening of the acetabular cup. Ten-year results of cementless THA with a sandwich-type alumina ceramic bearing were encouraging, and no great increase in ceramic failure rate was observed, which contrasts with the findings of previously reported short-term follow-up studies. PMID:21053885

  10. Cosmological Implications of the First Year Wilkinson Microwave Anisotropy Probe Results

    NASA Astrophysics Data System (ADS)

    Verde, L.

    The Wilkinson Microwave Anisotropy Probe (WMAP) team has recently analyzed and released the first-year data. We will review the implications for cosmology of these results. The highlight is that cosmology now has a standard cosmological model. With only 6 parameters the model fits not only WMAP data remarkably well, but also a host of other astronomical observations. We also present the results on neutrino mass limits and on dark energy properties from a joint likelihood analysis of WMAP data with small-scale CMB experiments and large-scale structure surveys. The data and supplementary information are publicly available and can be found on the experiment web site at .

  11. AMICA at Dome C: results from the first year of automatic operation tests in Antarctica

    NASA Astrophysics Data System (ADS)

    Dolci, M.; Valentini, A.; Ragni, M.; Di Cianno, A.; Di Rico, G.; Straniero, O.; Romano, D.; Christille, J.-M.; Piluso, A.

    2012-09-01

    Results from the first year of AMICA operations at Dome C are presented. AMICA is an astronomical camera for imaging between 2 and 24 μm designed to work automatically at the extreme conditions of Antarctica. Except for the cryostat, AMICA devices are hosted inside a rack whose operating conditions are automatically controlled. 120 days of environmental tests data have been obtained in 2011. The data concern the operating parameters of the system. The results show an excellent performance. A quality factor is computed as a function of the external conditions and a few critical correcting actions are described.

  12. Results and Implications of Seven Years of the University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    Walker-LaFollette, Amanda; Towner, A. P.; Hardegree-Ullman, K.; Brissenden, G.

    2014-01-01

    Participation in an undergraduate astronomy club or organization, be it social, academic, outreach-, or research-oriented, can be extremely beneficial to astronomy students. In this talk, we present the numerical results of the past seven years of University of Arizona Astronomy Club activities, particularly those relating to published papers, poster presentations, attendance at AAS meetings, and retention within the major. We also discuss less-quantifiable results, such as social, academic, and emotional support for club members. Finally, we highlight the efforts being performed by undergraduates at institutions all around the country, as presented in this Session.

  13. Results of proximal gastric vagotomy over 1-5 years in a district general hospital.

    PubMed

    Makey, D A; Tovey, F I; Heald, R J

    1979-01-01

    One hundred and seventy-three underwent proximal gastric vagotomy for duodenal ulceration over a 6-year period. One hundred and fifteen of these have been followed up for 1-5 years. The operative mortality was nil and the result was satisfactory in 91 per cent. The incidence of side effects was small, notably that of dumping being 2.4 per cent and of diarrhoea, 3.6 per cent. Incidence of postoperative heartburn was reduced from 13 per cent to 4 per cent by the introduction of hepatic interposition. The incidence of recurrent ulceration was 5.1 per cent after an average interval of 2 years and that of new gastric ulceration 2.6 per cent after an average of 4 years. There were no recurrent ulcers in those who had peroperative Burge tests, although secretory studies showed no difference between those tested and those not tested. Most recurrences occurred in the earliest cases operated on before Burge testing was introduced and when only 2 cm of the lower oesophagus were exposed. PMID:420970

  14. Allergen-Specific Immunotherapy in Patients 55 Years and Older: Results and Review of Literature

    PubMed Central

    Baptistella, Eduardo; Maniglia, Sergio; Malucelli, Diego Augusto; Rispoli, Daniel; Pruner de Silva, Thanara; Tsuru, Fernanda Miyoko; Becker, Renata Vecentin; Bernardi, Gustavo; Dranka, Daniela; Ferraz, Bruno

    2013-01-01

    Introduction Over the years the immune system suffers many morphologic and functional alterations, which result in a peak of function in puberty and a gradual decrease in the elderly. Aim Treat patients 55 years or older with allergic rhinitis with immunotherapy and then analyze the response to allergens. Materials and Methods From June 2009 to July 2010, 104 charts of patients 55 years or older with allergic complaints were evaluated. The patients were selected by anamnesis, physical examination, and otorhinolaryngologic exam. The patients had cutaneous test for mites before and after 1 year of sublingual specific immunotherapy. The cutaneous response was classified as negative (absent), light, moderate, or severe. Results Before vaccination, 42 (40.4%) patients were classified as having a severe form of allergy and 62 (59.6%) as having a moderate allergy. After the specific therapy, 40 (38.4%) patients were classified as negative (absent), 37 (35.6%) as light, 19 (18.3%) as moderate, and 8 (7.7%) as severe responses. Conclusion Immunotherapy, a desensitization technique, is indicated in cases which patients cannot avoid the exposure to allergens and in situations where pharmacologic therapy is not ideal. Specific immunotherapy to treat the allergic rhinitis in elderly patients was efficient and had no collateral effects, and in addition to the clinical benefit, improvement in the cutaneous test could also be observed. PMID:25992039

  15. Analysis of spirometry results in hospitalized patients aged over 65 years

    PubMed Central

    Wróblewska, Izabela; Oleśniewicz, Piotr; Kurpas, Donata; Sołtysik, Mariusz; Błaszczuk, Jerzy

    2015-01-01

    Introduction and objective The growing population of the elderly, as well as the occurrence of coexisting diseases and polypharmacy, is the reason why diseases of patients aged $65 years belong to the major issues of the contemporary medicine. Among the most frequent diseases of the elderly, there are respiratory system diseases. They are difficult to diagnose because of the patient group specificity, which is the reason for increased mortality among seniors, caused by underdiagnosis. The study objective was to assess the factors influencing spirometry results in hospitalized patients aged ≥65 years with respiratory system disorders. Material and methods In the research, 217 (100%) patients aged ≥65 years who underwent spirometry at the Regional Medical Center of the Jelenia Góra Valley Hospital in Poland were analyzed. In the statistical analysis, the STATISTICA 9.1 program, the t-test, the Shapiro–Wilk test, the ANOVA test, and the Scheffé’s test were applied. Results The majority of the patients (59.4%) were treated in the hospital. The most frequent diagnosis was malignant neoplasm (18%). The study showed a statistically significant dependence between the forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC parameters and the time of hospitalization, as well as between the FVC and FEV1 parameters and the age of patients. The FVC parameter values turned out to be dependent on the main diagnosis. Highest results were noted in patients with the diagnosis of sleep apnea or benign neoplasm. A low FVC index can reflect restrictive ventilation defects, which was supported by the performed analyses. Highest FEV1/FVC values were observed in nonsmokers, which confirms the influence of nicotine addiction on the incidence of respiratory system diseases. Conclusion The respondents’ sex and the established diagnosis statistically significantly influenced the FVC index result, and the diet influenced the FEV1/FVC parameter result

  16. New stable isotope results from a 173-year coral from Espiritu Santo, Vanuatu

    NASA Astrophysics Data System (ADS)

    Quinn, Terrence M.; Crowley, Thomas J.; Taylor, Frederick W.

    Long coral records provide valuable information on pentadal-decadal scale climate variability. Previously we have reported on a preliminary analysis of a 173-year record (1806-1978) from the island of Espiritu Santo (Republic of Vanuatu). Although this record contained information in the pentadal-decadal band, low sampling resolution raised questions about the validity of the results. Herein we report new data from the Santo record, in which the sampling resolution has been doubled and the validation database expanded. Variations in coral δ18O at Santo record the combined effects of variations in SST and rainfall-induced salinity changes. The most prominent spectral peaks in the time series are at the annual cycle and 14-15 and 7.4 years. The robust occurrence of the 14-15 year peak provides additional support to the importance of this oscillation as a cause of decadal-scale climate variability. Overall, our new results provide greater credibility to the conclusions raised in the earlier study and indicate that the Santo record can more confidently be incorporated into the still-small network of multicentury coral records of climate change.

  17. Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10 year prospective study

    PubMed Central

    Groves, C J; Saunders, B P; Spigelman, A D; Phillips, R K S

    2002-01-01

    Background: Duodenal cancer is one of the leading causes of death in familial adenomatous polyposis (FAP) patients. An endoscopic surveillance programme was therefore initiated in 1988, the outcome of which is described in this paper. Methods: We report the 10 year follow up of 114 patients with FAP who were prospectively screened for the presence and severity of duodenal adenomas. Results: Six of 114 patients (median age 67 years) developed duodenal adenocarcinoma. Four of these were from 11 patients who originally had Spigelman stage IV disease (advanced duodenal polyposis), which gives a 36% risk within this group of developing cancer. One case of duodenal cancer arose from 41 patients who originally had stage III disease (2%) and one cancer arose from 44 patients with original stage II disease (2%). All six patients have died: five were inoperable and one had recurrence three years after a pancreaticoduodenectomy. There was no association between duodenal cancer and site of germline mutation of the APC gene. Conclusions: Surveillance for duodenal adenocarcinoma and subsequent early referral for curative surgery has not been effective. Selection of patients with advanced but benign (Spigelman stage IV) duodenal polyposis for prophylactic pancreaticoduodenectomy should therefore be considered and can now be justified on the basis of these results. More comprehensive endoscopic surveillance of high risk (stage III and IV) patients is needed in an attempt to avoid underestimating the severity of duodenal polyposis, and to evaluate the role of endoscopic therapy in preventing advanced disease. PMID:11950808

  18. Natrelle 410 Extra-Full Projection Silicone Breast Implants: 2-Year Results from Two Prospective Studies

    PubMed Central

    McGuire, Patricia; Murphy, Diane K.

    2015-01-01

    Background: The safety and effectiveness of the Natrelle Style 410 highly cohesive silicone gel breast implant (Allergan, Inc., Irvine, Calif.) in full or moderate height and projection have been shown in a 10-year study. Extra-full projection implants may be an appropriate option for some women undergoing breast reconstruction. Methods: A total of 2795 women received at least one Natrelle 410 extra-full projection implant (X-style) for breast reconstruction in two similarly designed, prospective, multicenter studies. Data collected for 2 years after implantation in these studies were pooled to evaluate complication rates and subject and physician satisfaction. Results: Most subjects (76.0 percent) underwent bilateral reconstruction; a total of 4912 devices were implanted. Complication rates at 2 years were low. The most common complications were asymmetry (4.8 percent) and capsular contracture (3.3 percent). The cumulative risk of reoperation was 21.6 percent by subject and 16.6 percent by device; the most common reasons for reoperation were scarring (n = 97), asymmetry (n = 89), implant malposition (n = 78), and infection (n = 71). Subject and physician satisfaction rates exceeded 90 percent. At 2 years, 97 percent of physicians reported that the shape of the breast reflected the shape of the implant, and that the breast implant had maintained its original position. Conclusions: The safety profile of the Natrelle 410 extra-full projection implant mirrors that of its moderate projection and full projection counterparts. Both physicians and subjects were highly satisfied with the implants 2 years after surgery. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV. PMID:26090764

  19. The 3-year Solar Wind Charge Exchange Campaign with Suzaku: preliminary results

    NASA Astrophysics Data System (ADS)

    Ursino, Eugenio; Galeazzi, Massimiliano; Liu, Wenhao; Koutroumpa, Dimitra; Kuntz, K. D.

    2016-04-01

    We performed a 3-year monitoring campaign of the Solar Wind Charge Exchange (SWCX) heliospheric emission with Suzaku. We targeted four nearby (~100 pc) high column density clouds that absorb the X-ray contribution from distant sources so that the leftover signal has local origin (and is expected to be dominated by SWCX). The targets have been selected for their position in the sky, in order to maximize the latitude and longitude range, to model how SWCX depends on the distribution of neutrals, and to follow the seasonal variations of the SWCX. Here we present the results of data analysis of the three years of observations and we show how they compare with existing models.

  20. Does positive affect change in old age? Results from a 22-year longitudinal study.

    PubMed

    Gana, Kamel; Saada, Yaël; Amieva, Hélène

    2015-03-01

    The authors examined longitudinal change in positive affect (PA), a component of subjective well-being. Positive affect was assessed with the PA subscale of the Center for Epidemiologic Studies-Depression Scale (Radloff, 1977) in a sample of individuals from the PAQUID cohort (n = 3,777; age 62-101 years, M = 75.46, SD = 6.91 at Wave 1) over a period of 22 years (10 waves of data). Latent growth curve modeling was used to assess change in PA. A quadratic latent growth curve was found to characterize the latent growth pattern of PA in our sample, indicating linear change before a decline phase. These results were discussed with reference to the well-being paradox. PMID:25436598

  1. Patch-test results in children and adolescents: systematic review of a 15-year period*

    PubMed Central

    Rodrigues, Dulcilea Ferraz; Goulart, Eugênio Marcos Andrade

    2016-01-01

    The number of studies on patch-test results in children and adolescents has gradually increased in recent years, thus stimulating reviews. This paper is a systematic review of a 15-year period devoted to studying the issue. Variations pertaining to the number and age groups of tested children and/or adolescents, the number of subjects with atopy/atopic dermatitis history, the quantity, type and concentrations of the tested substances, the test technique and type of data regarding clinical relevance, must all be considered in evaluating these studies, as they make it harder to formulate conclusions. The most common allergens in children were nickel, thimerosal, cobalt, fragrance, lanolin and neomycin. In adolescents, they were nickel, thimerosal, cobalt, fragrance, potassium dichromate, and Myroxylon pereirae. Knowledge of this matter aids health professionals in planning preventive programs aimed at improving children's quality of life and ensuring that their future prospects are not undermined. PMID:26982781

  2. Biofilm formation and control in a simulated spacecraft water system - Two-year results

    NASA Technical Reports Server (NTRS)

    Schultz, John R.; Taylor, Robert D.; Flanagan, David T.; Carr, Sandra E.; Bruce, Rebekah J.; Svoboda, Judy V.; Huls, M. H.; Sauer, Richard L.; Pierson, Duane L.

    1991-01-01

    The ability of iodine to maintain microbial water quality in a simulated spacecraft water system is being studied. An iodine level of about 2.0 mg/L is maintained by passing ultrapure influent water through an iodinated ion exchange resin. Six liters are withdrawn daily and the chemical and microbial quality of the water is monitored regularly. Stainless steel coupons used to monitor biofilm formation are being analyzed by culture methods, epifluorescence microscopy, and scanning electron microscopy. Results from the first two years of operation show a single episode of high bacterial colony counts in the iodinated system. This growth was apparently controlled by replacing the iodinated ion exchange resin. Scanning electron microscopy indicates that the iodine has limited but not completely eliminated the formation of biofilm during the first two years of operation. Significant microbial contamination has been present continuously in a parallel noniodinated system since the third week of operation.

  3. Patch-test results in children and adolescents: systematic review of a 15-year period.

    PubMed

    Rodrigues, Dulcilea Ferraz; Goulart, Eugênio Marcos Andrade

    2016-02-01

    The number of studies on patch-test results in children and adolescents has gradually increased in recent years, thus stimulating reviews. This paper is a systematic review of a 15-year period devoted to studying the issue. Variations pertaining to the number and age groups of tested children and/or adolescents, the number of subjects with atopy/atopic dermatitis history, the quantity, type and concentrations of the tested substances, the test technique and type of data regarding clinical relevance, must all be considered in evaluating these studies, as they make it harder to formulate conclusions. The most common allergens in children were nickel, thimerosal, cobalt, fragrance, lanolin and neomycin. In adolescents, they were nickel, thimerosal, cobalt, fragrance, potassium dichromate, and Myroxylon pereirae. Knowledge of this matter aids health professionals in planning preventive programs aimed at improving children's quality of life and ensuring that their future prospects are not undermined. PMID:26982781

  4. Geology of the Southern Utopia Planitia Highland-Lowland Boundary Plain: Second Year Results and Third Year Plan

    NASA Technical Reports Server (NTRS)

    Skinner, J. A., Jr.; Tanaka, K. L.; Hare, T. M.

    2009-01-01

    The southern Utopia highland-lowland boundary (HLB) extends >1500 km westward from Hyblaeus Dorsa to the topographic saddle that separates Isidis and Utopia Planitiae. It contains bench-like platforms that contain depressions, pitted cones (some organized into arcuate chains and thumb-print terrain), isolated domes, buried circular depressions, ring fractures, polygonal fractures, and other locally- to regionally-dispersed landforms [1-2]. The objective of this map project is to clarify the geologic evolution of the southern Utopia Planitia HLB by identifying the geologic, structural, and stratigraphic relationships of surface materials in MTMs 10237, 15237, 20237, 10242, 15242, 20242, 10247, 15247, and 20247. The project was originally awarded in April, 2007 and is in its final year of support. Mapping is on-schedule and formal map submission will occur by December, 2009, with finalization anticipated by April, 2010. Herein, we (1) review specifics regarding mapping data and methods, (2) present nomenclature requests that we feel will assist with unit descriptions, (3) describe Year 2 mapping and science accomplishments, and (4) outline Year 3 technical and managerial approaches for finalizing the geologic map.

  5. A Pharmaceutical Bioethics Consultation Service: Six-Year Descriptive Characteristics and Results of a Feedback Survey

    PubMed Central

    Van Campen, Luann E.; Allen, Albert J.; Watson, Susan B.; Therasse, Donald G.

    2015-01-01

    Background: Bioethics consultations are conducted in varied settings, including hospitals, universities, and other research institutions, but there is sparse information about bioethics consultations conducted in corporate settings such as pharmaceutical companies. The purpose of this article is to describe a bioethics consultation service at a pharmaceutical company, to report characteristics of consultations completed by the service over a 6-year period, and to share results of a consultation feedback survey. Methods: Data on the descriptive characteristics of bioethics consultations were collected from 2008 to 2013 and analyzed in Excel 2007. Categorical data were analyzed via the pivot table function, and time-based variables were analyzed via formulas. The feedback survey was administered to consultation requesters from 2009 to 2012 and also analyzed in Excel 2007. Results: Over the 6-year period, 189 bioethics consultations were conducted. The number of consultations increased from five per year in 2008 to approximately one per week in 2013. During this time, the format of the consultation service was changed from a committee-only approach to a tiered approach (tailored to the needs of the case). The five most frequent topics were informed consent, early termination of a clinical trial, benefits and risks, human biological samples, and patient rights. The feedback survey results suggest the consultation service is well regarded overall and viewed as approachable, helpful, and responsive. Conclusions: Pharmaceutical bioethics consultation is a unique category of bioethics consultation that primarily focuses on pharmaceutical research and development but also touches on aspects of clinical ethics, business ethics, and organizational ethics. Results indicate there is a demand for a tiered bioethics consultation service within this pharmaceutical company and that advice was valued. This company's experience indicates that a bioethics consultation service raises

  6. One-Year Results of Bioresorbable Vascular Scaffolds for Coronary Chronic Total Occlusions.

    PubMed

    Vaquerizo, Beatriz; Barros, Antonio; Pujadas, Sandra; Bajo, Ester; Jiménez, Marcelo; Gomez-Lara, José; Jacobi, Francisco; Salvatella, Neus; Pons, Guillem; Cinca, Juan; Serra, Antonio

    2016-03-15

    The potential of bioresorbable vascular scaffold (BVS) technology has been demonstrated in first-in-man studies with up to 5-year follow-up. This study sought to investigate the 1-year outcomes of the BVS, for the treatment of chronic total occlusions (CTOs), using various imaging techniques. Thirty-five true CTO lesions treated with BVS were included in this prospective study. Scaffolds were deployed after mandatory predilation and intravascular ultrasound analysis. Optical coherence tomography was performed after BVS implantation and at 10 to 12 months. Multislice computed tomography was performed at baseline and at 6 to 8 months. Mean patient age was 61 ± 10 years. The most frequent vessel treated was the right coronary artery (46%). Lesions were classified as intermediate (49%) or difficult/very difficult (26%) according to the Japanese CTO complexity score. Predilation was performed in 100% of lesions, using cutting balloons in 71% of these. The total scaffold length implanted per lesion was of 52 ± 23 mm. All scaffolds were delivered and deployed successfully. Postdilation was undertaken in 63%. By multislice computed tomography at 6 months, we observed 2 cases of asymptomatic scaffold restenosis, subsequently confirmed by angiography. At 12 months, no scaffold thrombosis or major adverse cardiac events were reported. The optical coherence tomography at follow-up showed that 94% of struts were well apposed and covered (5% of uncovered struts and 1% of nonapposed struts), and only 0.6% of struts were nonapposed and uncovered. In conclusion, 1-year results suggest that BVS for CTO is associated with excellent clinical and imaging outcomes. Accurate percutaneous coronary BVS technique might have enabled these promising results. PMID:26874547

  7. Preliminary Third Year Results from the Python Microwave Background Anisotropy Experiment

    NASA Astrophysics Data System (ADS)

    Platt, S. R.; Dragovan, M.; Ruhl, J. E.; Kovak, J.

    1995-05-01

    We report preliminary results from the third year of observations from Amundsen-Scott South Pole Station with the Python microwave background anisotropy experiment. The instrument is a five channel bolometer array, with detectors operating at 50 mK, cooled by a hybrid (3) He-Adiabatic demagnetization refrigerator. Single-mode waveguide optics center the passband at 90 GHz, and couple the detector system to the 0.75m off-axis parabolic primary mirror of the telescope. The measured beamwidths are 0.75(deg) . We combine a fast 5 Hz 3-beam chop of a vertical flat plate with slow .025 Hz telescope beamswitches to produce a gradient-free 4-beam pattern on the sky. The chop amplitude is 2.75(deg) . In each of the first two years of observations with this system we scanned the same 22 fields, centered at alpha = 23.32, delta = -49.5. In both years we detected statistically significant fluctuations with an amplitude of Delta T / T ~ 3.3 times 10(-5) for an anisotropy model with a Gaussian autocorrelation function with a coherence angle of theta_c = 1(deg) . Our new results incorporate observations made in December 1994 that intersperse these fields and sample more fully this region of sky. The entire three year data set will be used to make a difference map of the structure of anisotropy at intermediate angular scales across a 6(deg) times 22(deg) region of sky. This work was supported by the National Science Foundation under a cooperative agreement with the Center for Astrophysical Research in Antarctica (CARA), grant number NSF OPP 89-20223, M.D.'s PYI grant NSF AST 90-57089, and the James S. McDonnell Foundation. CARA is a National Science Foundation Science and Technology Center.

  8. Five-year results of a cementless short-hip-stem prosthesis

    PubMed Central

    Wittenberg, Ralf H.; Steffen, Reinhard; Windhagen, Henning; Bücking, Petra; Wilcke, Andreas

    2013-01-01

    Hip prosthesis stems with a short stem length and proximal fixation geometry support a bone-preserving and muscle-sparing implantation and should also allow for revision surgery with a standard hip stem. We present 250 prospectively documented clinical and radiological results from the Metha Short Hip Stem prosthesis (B. Braun-Aesculap, Tuttlingen, Germany) after an average follow-up of 4.9 years. The average patient age at surgery was 60 years. Indication for total hip replacement was primary osteoarthrosis (OA) (78% of patients), OA based on developmental dysplasia of the hip (16%), and other indications (6%). At the last follow-up, the average Harris Hip Score was 97 points. 85% of patients were very satisfied and 14% were satisfied after surgery, whereas 1% were dissatisfied. Pain according to the Visual Analogue Scale improved from 7.4 (min 1.6, max 9.5) pre-operatively to 0.23 (min 0, max 6.6). No joint dislocations occurred when predominantly using 28 mm and 32 mm prosthesis heads. Nine short-stems were revised: three after bacterial infections, two after primary via valsa with penetration of the femoral cortex two and three months after surgery, and three after early aseptic cases of loosening within the first year. A further nine osseously consolidated short-stems had to be replaced due to breakage of the modular titanium cone adapter after an average of 3.1 years (min 1.9, max 4.4). All surgical revisions were performed using primary standard stems. Without taking the material-related adapter failures into account, a five year Kaplan-Meier survival rate of 96.7% (95% confidence interval 93.4–98.3) was determined for the short-stem prostheses. There were no radiological signs of loosening in any of the short-stem prostheses at the last examination. Fine sclerotic lines were detected in Gruen's AP zones 1 (19%) and 2 (10.5%), individual hypertrophies in zone 3 (3.5%), fine seams in zones 4 (5.5%) and 5 (4%), without pedestal formations in zone 4, clear

  9. [15-year results following implantation of a stem type AML hip prosthesis].

    PubMed

    Schwerter, K; Meyenberg, A; Sander, K; Layher, F; Roth, A

    2013-06-01

    The trend in arthroplasty of the hip joint to implement new models is partly based on theoretical considerations. In order to verify to which extent the philosophy of individual models is ultimately successful, the presentation of long-term results is required. In the years 1991 and 1992, 433 patients with primary implantation of an uncemented total hip replacement in primary coxarthrosis with a stem type AML (anatomic medullary locking) were treated surgically. 283 of them got a cementless cup type Duraloc. In 311 (71.8 %) patients the mean survival rate of the prosthesis could be determined at a mean follow-up of 15.5 years. 145 (33.5 %) patients were followed up completely both clinically and radiologically. Radiographically, the stem position, changes of the periprosthetic bone of the stem and the cup, as well as the wear of the cups were examined. The cumulative survival rate of the AML stem after 15.5 years was 97.5 %, of the Duraloc cup 88.2 %. The clinical results of the hip scores according to Harris and Merle d'Aubigné were good and excellent and patient satisfaction was very high. There was no relationship between stem position, stress shielding and surrounding lyses at the femur and the acetabulum and survival of stem or cup. There was no correlation between inlay wear and survival of the Duraloc cup. A subsiding of the stem in 2 cases had no effect on the clinical symptoms and quality of life. The press-fit implanted AML stem and the Duraloc cup revealed very good results during the investigation period. Like other implants, the survival rate is limited at the presented implant mainly by the cup. PMID:23696163

  10. Long term compatibility of nitrogen tetroxide with metals - Results at the ten-year milestone

    NASA Technical Reports Server (NTRS)

    Moran, C. M.; Bjorklund, R. A.

    1982-01-01

    Analyses and results are reported of a test program to establish the effects of long-term (10 years or more) contact of materials with nitrogen textroxide MON-1 for the purpose of designing chemical propulsion system components which can be used for current as well as future planetary spacecraft. The test materials included aluminum alloy, corrosion-resistant steel, titanium alloy, and nickel. The weight and appearance of each specimen were observed, including the presence of deposits, etching, pitting, and cracking. Aluminum alloy and steel were rated satisfactory with minor reservations, titanium alloy was satisfactory, and nickel was unsatisfactory. Criteria for ratings are shown.

  11. Results from Three Years of Ka-Band Propagation Characterization at Svalbard, Norway

    NASA Technical Reports Server (NTRS)

    Nessel, James; Zemba, Michael; Morse, Jacquelynne

    2015-01-01

    Over the next several years, NASA plans to launch several earth science missions which are expected to achieve data throughputs of 5-40 terabits per day transmitted from low earth orbiting spacecraft to ground stations. The current S-band and X-band frequency allocations in use by NASA, however, are incapable of supporting the data rates required to meet this demand. As such, NASA is in the planning stages to upgrade its existing Near Earth Network (NEN) polar ground stations to support Ka-band (25.5-27 GHz) operations. Consequently, it installed and operated a Ka-band radiometer at the Svalbard site. Svalbard was chosen as the appropriate site for two primary reasons: (1) Svalbard will be the first site to be upgraded to Ka-band operations within the NEN Polar Network enhancement plan, and (2) there exists a complete lack of Ka-band propagation data at this site (as opposed to the Fairbanks, AK NEN site, which has 5 years of characterization collected during the Advanced Communications Technology becomes imperative that characterization of propagation effects at these NEN sites is conducted to determine expected system Satellite (ACTS) campaign). processing and provide the Herein, we discuss the data three-year measurement results performance, particularly at low elevation angles ((is) less than 10 deg) from the ongoing Ka-band propagation characterization where spacecraft signal acquisition typically occurs. Since May 2011, NASA Glenn Research Center has installed and operated a Ka-band radiometer at the NEN site located in Svalbard, Norway. The Ka-band radiometer monitors the water vapor line, as well as 4 frequencies around 26.5 GHz at a fixed 10 deg elevation angle. Three-year data collection results indicate good campaign at Svalbard, Norway. Comparison of these results with the ITU models and existing ERA profile data indicates very good agreement when the 2010 rain maps and cloud statistics are used. Finally, the Svalbard data is used to derive the expected

  12. Results from Three Years of Ka-band Propagation Characterization at Svalbard, Norway

    NASA Technical Reports Server (NTRS)

    Nessel, James A.; Zemba, Michael; Morse, Jacquelynne

    2015-01-01

    Over the next several years, NASA plans to launch several earth science missions which are expected to achieve data throughputs of 5-40 terabits per day transmitted from low earth orbiting spacecraft to ground stations. The current S-band and X-band frequency allocations in use by NASA, however, are incapable of supporting the data rates required to meet this demand. As such, NASA is in the planning stages to upgrade its existing Near Earth Network (NEN) polar ground stations to support Ka-band (25.5-27 GHz) operations. Consequently, it installed and operated a Ka-band radiometer at the Svalbard site. Svalbard was chosen as the appropriate site for two primary reasons: (1) Svalbard will be the first site to be upgraded to Ka-band operations within the NEN Polar Network enhancement plan, and (2) there exists a complete lack of Ka-band propagation data at this site (as opposed to the Fairbanks, AK NEN site, which has 5 years of characterization collected during the Advanced Communications Technology becomes imperative that characterization of propagation effects at these NEN sites is conducted to determine expected system Satellite (ACTS) campaign). processing and provide the Herein, we discuss the data three-year measurement results performance, particularly at low elevation angles ((is) less than 10 deg) from the ongoing Ka-band propagation characterization where spacecraft signal acquisition typically occurs. Since May 2011, NASA Glenn Research Center has installed and operated a Ka-band radiometer at the NEN site located in Svalbard, Norway. The Ka-band radiometer monitors the water vapor line, as well as 4 frequencies around 26.5 GHz at a fixed 10 deg elevation angle. Three-year data collection results indicate good campaign at Svalbard, Norway. Comparison of these results with the ITU models and existing ERA profile data indicates very good agreement when the 2010 rain maps and cloud statistics are used. Finally, the Svalbard data is used to derive the expected

  13. First Year Results from the Fermi Gamma-Ray Space Telescope

    NASA Technical Reports Server (NTRS)

    Hays, Elizabeth

    2009-01-01

    After one year of survey observations and more than 70 billion triggers, Fermi is revealing an unprecedented view of the high energy gamma-ray sky. The observatory .carries two instruments, the Gamma-ray Burst Monitor (GB, 8 keV - 40 MeV) and the Large Area Telescope (LAT, 20 MeV greater than or equal to 300 GeV), which in combination cover over 7 orders of magnitude in energy for transient phenomena. The LAT provides substantially more sensitivity than previous instruments in this waveband and has opened up the energy window from 10-100 GeV. The first year has produced many important results, from detections of extremely energetic and distant gamma-ray bursts, to monitoring daily variations in emission caused by massive black holes at the cores of galaxies, to identifying a new population of gamma-ray bright pulsars, to measuring the spectrum of diffuse emission from our own. Galaxy and the spectrum of the local cosmic electrons. I'll review highlights from the first year and discuss how the data are answering questions from the past and raising new ones for the future.

  14. [Transitory bone loss during substitution treatment for hypothyroidism. Results of a two year prospective study].

    PubMed

    Trémollières, F; Pouillès, J M; Louvet, J P; Ribot, C

    1991-12-01

    The authors report the results of a prospective study designed to assess changes in vertebral and femoral bone density during the first two years of replacement therapy in 10 patients with hypothyroidism (4 men, 6 women). During the first year, bone density measured by dual photon absorptiometry fell significantly in the lumbar vertebrae (-5.4%), neck of the femur (-7%) and the trochanteric region (-7.3%). This bone loss was accompanied by an early increase in serum osteocalcin levels, urinary calcium/urinary creatinine ratio and in Sex Hormone Binding Globulin. During the second year, there was complete recovery of values of vertebral and trochanteric bone density, while density of the neck of the femur remained significantly lower than initial values. None of the patients showed any evidence of overdose during the period of monitoring of clinical and laboratory (free T4, total and free T3, ultra-sensitive TSH) parameters. This transitory bone loss could be indicative of a state of tissue hyperthyroidism and/or "hypersensitivity" of hypothyroid bone to the action of thyroid hormones. Its influence on the subsequent risk of fracture remains unclear. In the current state of knowledge, measurement of vertebral and femoral bone density appears to be indicated in patients given long term treatment which suppresses TSH, or requiring replacement therapy for severe hypothyroidism. Any demineralisation prior to treatment could justify the temporary prescription of an antiosteoclastic agent. PMID:1780668

  15. Alternative fuel vehicles for the state fleets: Results of the 5-year planning process

    SciTech Connect

    Not Available

    1993-05-01

    This report documents the first attempt by the Department of Energy (DOE) to work with states to prepare five-year Alternative Fuel Vehicle (AFV) acquisition plans to identify alternative fuels and vehicles that they are planning on or would like to acquire. The DOE Regional Support Offices (RSOs) met with representatives from the states in their regions and assisted in the preparation of the plans. These plans will be used in conjunction with previously gathered Federal five-year plans to encourage Original Equipment Manufacturers (OEMs) to expand the variety of AFVs produced, reduce the incremental cost of AFVs, and to encourage fuel suppliers to expand the alternative fuel infrastructure and alternative fuel availability. By identifying the needs and requirements of state fleets, DOE can begin to describe the specific nature of the future state fleets, and establish a defined market for OEMs and fuel suppliers. DOE initiated the development and collection of the state five-year plans before the signing of the Energy Policy Act, to raise the awareness of states that they will be required by law to acquire AFVs. As a result, several states that had no AFV acquisition plan when queried have developed or are in the process of developing plans. The DOE and its RSOs are still working with the states to develop and refine acquisition plans, and this report should be treated as documentation of work in progress.

  16. Visual, refractive, and keratometric results of epikeratophakia in children. A two-year follow-up.

    PubMed

    Uusitalo, R J; Lehtosalo, J

    1989-03-01

    Fifty-two patients under the age of 16 years (68 eyes) received epikeratophakia grafts for the correction of aphakia. In 27 eyes, epikeratophakia was a primary procedure combined with lensectomy. Fifteen children underwent bilateral surgery. Overall, the success rate was 91%, and with repeated surgery it was 94%. The average change in refractive error was 15.9 diopters (D) and the average spectacle overcorrection was +0.3 D. Sixty-one percent (35/57) of the eyes were within 1 D of emmetropia and 97% (55/57) were within 3 D of emmetropia. Overall, the refraction was stable in the follow-up between six months and 1 1/2 years following surgery. However, a myopic shift of 2.0 D occurred between six months and 1 1/2 years in very young children following refractive surgery. The corneal curvature was measured only in older children and showed an average increase of 10.7 D. Visual acuity results in verbal patients were comparable to those in patients with contact lenses. The majority of smaller children demonstrated improvement in visual acuity with a combination of epikeratophakia and amblyopia therapy. PMID:2647066

  17. Two-year moored instrument results along 152 deg E. [of North Pacific

    NASA Technical Reports Server (NTRS)

    Schmitz, William J., Jr.; Niiler, Pearn P.; Koblinsky, Chester J.

    1987-01-01

    Results from a 2-year (nominal) deployment of a moored array along 152 deg E from 28 deg N to 41 deg N are presented, with emphasis on similarities and differences between settings (approximately year-to-year). Ten moorings and 38 instruments were involved, from the fall of 1980 to 1982. Current-temperature meters spanned the water column from 500- to 4000-m depths, with occasional instruments in the vicinity of 300 m and near the bottom (about 6000 m). Upper level features located in the center of the array near 35-36 deg N were generally stable relative to the axis of the Kuroshio Extension, varying from deployment to deployment with meanders in this flow regime. Some properties of the abyssal (about 4000 m) currents were comparatively more variable, with these changes not connected to meandering of the Kuroshio Extension in an obvious way. The vertical structure and frequency distributions of eddy kinetic energy were similar in shape and to some extent in amplitude from deployment to deployment, especially relative to meanders of the Kuroshio Extension, but translated in the opposite direction.

  18. 2-year outcomes in Initial survivors with Acute Liver failure: Results from a Prospective, Multicenter Study

    PubMed Central

    Fontana, Robert J.; Ellerbe, Caitlyn; Durkalski, Valerie E.; Rangnekar, Amol; Reddy, K. Rajender; Stravitz, Todd; McGuire, Brendan; Davern, Timothy; Reuben, Adrian; Liou, Iris; Fix, Oren; Ganger, Daniel R; Chung, Raymond T.; Schilsky, Mike; Han, Steven; Hynan, Linda S.; Sanders, Corron; Lee, William M.

    2014-01-01

    BACKGROUND The long-term clinical outcomes in initial survivors with acute liver failure (ALF) are not well known. AIMS The aim of the current study is to provide an overview of the 2 year clinical outcomes amongst initial survivors and liver transplant (LT) recipients that were alive 3 weeks after enrollment in the Acute Liver Failure Study Group (ALFSG). METHODS Outcomes in adult ALFSG patients that were enrolled between 1998 and 2010 were reviewed. RESULTS 2-year patient survival was significantly higher in the 262 LT recipients (92.4%) compared to the 306 acetaminophen (APAP) spontaneous survivors (SS) (89.5%) and 200 non-APAP SS (75.5%) (p < 0.0001). The causes of death were similar in the 3 groups but the time to death was significantly longer in the LT recipients (p< 0.0001). Independent predictors of 2-year mortality in the APAP group were a high serum phosphate level and patient age (c-statistic = 0.65 (0.54, 0.76)), patient age and days from jaundice to ALF onset in the non-APAP group (c-statistic =0.69 (0.60, 0.78)), and patient age, days from jaundice, and higher coma grade in the LT recipients (c-statistic=0.74 (0.61, 0.87)). The LT recipients were significantly more likely to be employed and have a higher educational level (p < 0.05). CONCLUSIONS Two-year outcomes in initial survivors of ALF are generally good but non-APAP patients have a significantly lower survival which may relate to pre-existing medical co-morbidities. Spontaneous survivors with APAP overdose experience substantial morbidity during follow-up from ongoing psychiatric and substance abuse issues. PMID:25039930

  19. Glaucoma-related Adverse Events in the Infant Aphakia Treatment Study (IATS) : One Year Results

    PubMed Central

    Beck, AD; Freedman, SF; Lynn, MJ; Bothun, ED; Neely, D; Lambert, SR

    2012-01-01

    Objective To report the incidence of glaucoma and glaucoma suspects in the Infant Aphakia Treatment Study (IATS). To evaluate risk factors for the development of a glaucoma-related adverse event in IATS in the first year of follow-up. Methods 114 infants with a unilateral congenital cataract were assigned to undergo cataract surgery between 1 to 6 months of age either with (IOL) or without IOL implantation (CL). Standardized definitions of glaucoma and glaucoma suspect were created and used in the IATS. Results Ten patients (9%) developed glaucoma and 4 patients (4%) were glaucoma suspects for a total of 14 patients (12%) with a glaucoma-related adverse event in the treated eye through the first year of follow-up. Five CL patients (9%) and 9 IOL patients (16%) developed a glaucoma-related adverse event. The odds of developing a glaucoma-related adverse event was 3.1 times higher for a child with persistent fetal vasculature (PFV), and 1.6 times higher for each month of age younger at cataract surgery. Conclusions Modern surgical techniques do not eliminate the early development of glaucoma following congenital cataract surgery with or without an intraocular lens. Younger patients with or without PFV seem more likely to develop a glaucoma-related adverse event in the first year of follow-up.Vigilance for the early development of glaucoma is needed following congenital cataract surgery, especially when surgery is performed during early infancy or with PFV. Five year follow-up data for the IATS will likely reveal more glaucoma-related adverse events. PMID:22084157

  20. Partial Breast Radiation Therapy With Proton Beam: 5-Year Results With Cosmetic Outcomes

    SciTech Connect

    Bush, David A.; Do, Sharon; Lum, Sharon; Garberoglio, Carlos; Mirshahidi, Hamid; Patyal, Baldev; Grove, Roger; Slater, Jerry D.

    2014-11-01

    Purpose: We updated our previous report of a phase 2 trial using proton beam radiation therapy to deliver partial breast irradiation (PBI) in patients with early stage breast cancer. Methods and Materials: Eligible subjects had invasive nonlobular carcinoma with a maximal dimension of 3 cm. Patients underwent partial mastectomy with negative margins; axillary lymph nodes were negative on sampling. Subjects received postoperative proton beam radiation therapy to the surgical bed. The dose delivered was 40 Gy in 10 fractions, once daily over 2 weeks. Multiple fields were treated daily, and skin-sparing techniques were used. Following treatment, patients were evaluated with clinical assessments and annual mammograms to monitor toxicity, tumor recurrence, and cosmesis. Results: One hundred subjects were enrolled and treated. All patients completed the assigned treatment and were available for post-treatment analysis. The median follow-up was 60 months. Patients had a mean age of 63 years; 90% had ductal histology; the average tumor size was 1.3 cm. Actuarial data at 5 years included ipsilateral breast tumor recurrence-free survival of 97% (95% confidence interval: 100%-93%); disease-free survival of 94%; and overall survival of 95%. There were no cases of grade 3 or higher acute skin reactions, and late skin reactions included 7 cases of grade 1 telangiectasia. Patient- and physician-reported cosmesis was good to excellent in 90% of responses, was not changed from baseline measurements, and was well maintained throughout the entire 5-year follow-up period. Conclusions: Proton beam radiation therapy for PBI produced excellent ipsilateral breast recurrence-free survival with minimal toxicity. The treatment proved to be adaptable to all breast sizes and lumpectomy cavity configurations. Cosmetic results appear to be excellent and unchanged from baseline out to 5 years following treatment. Cosmetic results may be improved over those reported with photon

  1. Porous-coated acetabular components with screw fixation. Five to ten-year results.

    PubMed

    Latimer, H A; Lachiewicz, P F

    1996-07-01

    The results of 136 consecutive primary total hip arthroplasties performed by one surgeon with the Harris-Galante-I porous-coated acetabular component were reviewed at a mean of seven years (range, five to ten years). In all hips, the outer diameter of the acetabular component was the same as the diameter of the final reamer used in the preparation of the acetabulum. However, this reamer was used only briefly at the rim of the acetabulum, and therefore the components had so-called press-fit stability. A mean of four screws (range, three to six screws) were used for additional fixation of the component. The clinical evaluation was performed with use of the Harris hip score. Standardized anteroposterior radiographs of the pelvis were assessed for migration of the component, radiolucent and radiodense lines, linear wear of the polyethylene, and osteolysis. No acetabular component had been revised for loosening and none were radiographically loose at the time of the most recent follow-up evaluation. There were no complications related to the use of the screws, and no screw had bent or broken. A non-progressive radiolucent line was seen in one acetabular zone in thirty-four hips (25 per cent) and in two acetabular zones in six hips (4 per cent). No hip had a radiolucent line in all three acetabular zones. The mean rate of linear wear of the polyethylene was 0.1 millimeter per year. There was no dissociation of the acetabular liner from the metal shell. Two hips (1 per cent) had asymptomatic osteolysis in the ischium and adjacent to the rim of the acetabular component; this was treated with grafting at the site of the lesion and exchange of the femoral head and the worn polyethylene liner. Five femoral components inserted without cement and one inserted with cement were revised because of loosening. The data suggest that, at a mean of seven years, fixation of this porous-coated component was uniformly excellent. The low prevalence of radiolucent lines and the absence of

  2. Improvement in the Results of Surgical Treatment of Advanced Squamous Esophageal Carcinoma During 15 Consecutive Years

    PubMed Central

    Ando, Nobutoshi; Ozawa, Soji; Kitagawa, Yuko; Shinozawa, Yotaro; Kitajima, Masaki

    2000-01-01

    Objective To document the clinicopathologic characteristics and survival of patients undergoing esophagectomy for squamous carcinoma of the thoracic esophagus, and to examine the factors contributing to improvements in outcome noted in patients with advanced carcinoma. Summary Background Data Japanese and some Western surgeons recently have reported that radical esophagectomy with extensive lymphadenectomy conferred a survival advantage to patients with esophageal carcinoma. The factors contributing to this improvement in results have not been well defined. Methods From 1981 to 1995, 419 patients with carcinoma of the thoracic esophagus underwent esophagectomy at the Keio University Hospital. The clinicopathologic characteristics and survival of patients treated between 1981 and 1987 were compared with those of patients treated between 1988 and 1995. Multivariate analysis using the Cox regression model was carried out to evaluate the impact of 15 variables on survival of patients with p stage IIa to IV disease. Several variables related to prognosis were examined to identify differences between the two time periods. Results The 5-year survival rate for all patients was 40.0%. The 5-year survival rate was 17.7% for p stage IIa to IV patients treated during the earlier period and 37.6% for those treated during the latter period. The Cox regression model revealed seven variables to be important prognostic factors. Of these seven, three (severity of postoperative complications, degree of residual tumor, and number of dissected mediastinal nodes) were found to be significantly different between the earlier and latter periods. Conclusions The survival of patients undergoing surgery for advanced carcinoma (p stage IIa to IV) of the thoracic esophagus has improved during the past 15 years. The authors’ data suggest that this improvement is due mainly to advances in surgical technique and perioperative management. PMID:10903602

  3. Six-year in-vitro reliability results of the HeartWare HVAD pump.

    PubMed

    Reyes, Carlos; Chorpenning, Katherine; LaRose, Jeffrey A; Gomez, Ramiro; Tamez, Daniel

    2014-01-01

    As a result of stagnant heart transplantation rates, ventricular assist devices (VADs) have become a widely accepted therapy for the treatment of advanced-stage heart failure. Long-term reliability of VADs will become increasingly vital as the population of destination therapy patients expands. In this study, eight HVAD pumps (n = 8) completed a 6-year reliability test in the HeartWare Life Cycle Testing System, an in-vitro mock circulatory loop that simulated physiologic pressures and flows. Cumulative runtime for the pumps was 2,408 ± 60 days. During this time, no device failures of any type occurred. These results strongly support the durability of the pump design. PMID:24814839

  4. Control of soil-transmitted helminthiasis in Myanmar: results of 7 years of deworming.

    PubMed

    Tun, Aung; Myat, Su Mon; Gabrielli, Albis Francesco; Montresor, Antonio

    2013-08-01

    After a baseline survey in 2003 which showed an overall parasitological prevalence of soil-transmitted helminths of 69.7% in school children (prevalence of ascariasis 48.5%, prevalence of trichuriasis 57.5% and prevalence of hookworm infection 6.5), a national deworming programme was established. After 7 years of implementation, it had resulted in a significant reduction of STH prevalence (prevalence of any STH 21%, prevalence of ascariasis 5.8%, prevalence of trichuriasis 18.6% and prevalence of hookworm infection 0.3%) as well as a reduction of the infections of moderate-heavy intensity from 18.5% at baseline to less than 7%. The results are encouraging and a reduction of the frequency of deworming can be envisaged in two of four ecological areas of Myanmar. PMID:23701018

  5. ENVIRONMENTAL RADIATION MONITORING IN THE CHERNOBYL EXCLUSION ZONE - HISTORY AND RESULTS 25 YEARS AFTER

    SciTech Connect

    Farfan, E.; Jannik, T.

    2011-10-01

    This article describes results of the radiation environmental monitoring performed in the Chernobyl Exclusion Zone (ChEZ) during the period following the 1986 Chernobyl Nuclear Power Plant accident. This article presents a brief overview of five comprehensive reports generated under Contract No. DE-AC09-96SR18500 (Washington Savannah River Company LLC, Subcontract No. AC55559N, SOW No. ON8778) and summarizes characteristics of the ChEZ and its post-accident status and the history of development of the radiation monitoring research in the ChEZ is described. This article addresses characteristics of the radiation monitoring in the ChEZ, its major goals and objectives, and changes of these goals and objectives in the course of time, depending on the tasks associated with the phase of mitigation of the ChNPP accident consequences. The results of the radiation monitoring in the ChEZ during the last 25 years are also provided.

  6. Cosmological Implications of the First Year Wilkinson Microwave Anisotropy Probe Results

    NASA Astrophysics Data System (ADS)

    Verde, L.

    2004-02-01

    The Wilkinson Microwave Anisotropy Probe (WMAP) team has recently analyzed and released the first-year data. We will review the implications for cosmology of these results. The highlight is that cosmology now has a standard cosmological model. With only 6 parameters the model fits not only WMAP data remarkably well, but also a host of other astronomical observations. We also present the results on neutrino mass limits and on dark energy properties from a joint likelihood analysis of WMAP data with small-scale CMB experiments and large-scale structure surveys. The data and supplementary information are publicly available and can be found on the experiment web site at .

  7. Amiba:. First-Year Results for SUNYAEV-ZEL'DOVICH Effect

    NASA Astrophysics Data System (ADS)

    Wu, Jiun-Huei Proty; Chiueh, Tzi-Hong; Huang, Chi-Wei; Liao, Yao-Wei; Wang, Fu-Cheng; Altimirano, Pablo; Chang, Cha-Hao; Chang, Su-Hao; Chang, Su-Wei; Chen, Ming-Tang; Chereau, Guillaume; Han, Chih-Chiang; Ho, Paul T. P.; Huang, Yao-De; Hwang, Yuh-Jing; Jiang, Homin; Koch, Patrick; Kubo, Derek; Li, Chao-Te; Lin, Kai-Yang; Liu, Guo-Chin; Martin-Cocher, Pierre; Molnar, Sandor; Nishioka, Hiroaki; Raffin, Philippe; Umetsu, Keiichi; Kesteven, Michael; Wilson, Warwick; Birkinshaw, Mark; Lancaster, Katy

    We discuss the observation, analysis, and results of the first-year science operation of AMiBA, an interferometric experiment designed to study cosmology via the measurement of Cosmic Microwave Background (CMB). In 2007, we successfully observed 6 galaxy clusters (z < 0.33) through the Sunyaev-Zel'dovich effect. AMiBA is the first CMB interferometer operating at 86-102 GHz, currently with 7 close-packed antennas of 60 cm in diameter giving a synthesized resolution of around 6 arcminutes. An observing strategy with on-off-source modulation is used to remove the effects from electronic offset and ground pickup. Formalism of the analysis is given and preliminary science results are summarized. Tests for systematic effects are also addressed. We also discuss the expansion plan.

  8. Results from Two Years of Ka-Band Propagation Characterization at Svalbard, Norway

    NASA Technical Reports Server (NTRS)

    Nessel, James A.; Morse, Jacquelynne Rose; Zemba, Michael

    2014-01-01

    Over the several years, NASA plans to launch several earth science missions which are expected to achieve data throughputs of 5-40 terabits per day transmitted from low earth orbiting spacecraft to ground stations. The current S-band and X-band frequency allocations in use by NASA, however, are incapable of supporting the data rates required to meet this demand. As such, NASA is in the planning stages to upgrade its existing Near Earth Network (NEN) Polar ground stations to support Ka-band (25.5-27 GHz) operations. Consequently, it becomes imperative that characterization of propagation effects at these NEN sites is conducted to determine expected system performance, particularly at low elevation angles ((is) less than 10 deg) where spacecraft signal acquisition typically occurs. Since May 2011, NASA Glenn Research Center has installed and operated a Ka-band radiometer at the NEN site located in Svalbard, Norway. The Ka-band radiometer monitors the water vapor line, as well as 6 frequencies around 26.5 GHz at multiple elevation angles: 45 deg, 20 deg, and 10 deg. Two year data collection results indicate comparable performance to previously characterized northern latitude sites in the United States, i.e., Fairbanks, Alaska. It is observed that cloud cover at the Svalbard site remains the dominant loss mechanism for Ka-band links, resulting in a margin requirement of 4.1 dB to maintain link availability of 99% at 10 deg elevation.

  9. The effects of Crew Resource Management (CRM) training in airline maintenance: Results following three year's experience

    NASA Technical Reports Server (NTRS)

    Taylor, J. C.; Robertson, M. M.

    1995-01-01

    An airline maintenance department undertook a CRM training program to change its safety and operating culture. In 2 1/2 years this airline trained 2200 management staff and salaried professionals. Participants completed attitude surveys immediately before and after the training, as well as two months, six months, and one year afterward. On-site interviews were conducted to test and confirm the survey results. Comparing managers' attitudes immediately after their training with their pretraining attitudes showed significant improvement for three attitudes. A fourth attitude, assertiveness, improved significantly above the pretraining levels two months after training. The expected effect of the training on all four attitude scales did not change significantly thereafter. Participants' self-reported behaviors and interview comments confirmed their shift from passive to more active behaviors over time. Safety, efficiency, and dependability performance were measured before the onset of the training and for some 30 months afterward. Associations with subsequent performance were strongest with positive attitudes about sharing command (participation), assertiveness, and stress management when those attitudes were measured 2 and 12 months after the training. The two month follow-up survey results were especially strong and indicate that active behaviors learned from the CRM training consolidate and strengthen in the months immediately following training.

  10. Nail Psoriasis in Children: Common or Uncommon? Results from a 10-Year Double-Center Study

    PubMed Central

    Piraccini, Bianca Maria; Triantafyllopoulou, Ioanna; Prevezas, Christos; Starace, Michela; Neri, Iria; Patrizi, Annalisa; Caserini, Maurizio; Palmieri, Renata; Rigopoulos, Dimitrios

    2015-01-01

    Purpose of the Study Our aim was to perform an extensive search of the literature on the prevalence of nail psoriasis in the pediatric population and to estimate it on our own database. Procedures Searching the most important databases yielded results of 16 papers published in a 40-year period which reported the prevalence of nail psoriasis in children. Furthermore, data gathered between 2004 and 2013 at two centers specialized in nail disorders were analyzed. Results The selected papers encompassed a total of 4,853 psoriatic children, of whom 762 (15.7%) had nail involvement. Concerning our data, a total of 68,839 children were seen in pediatric skin consultation in both clinics over a period of 10 years, 0.11% of which had nail involvement. The rate of psoriatic children presenting nail alterations was 19.4% in the Greek and 15.5% in the Italian patient groups. Conclusions and Message This is the retrospective study including the largest number of cases of nail psoriasis in the pediatric population. Our data are in line with the incidence estimation of the rest of Europe. PMID:27172521

  11. Results from the first year of the HAWC Gamma Ray Observatory

    NASA Astrophysics Data System (ADS)

    Goodman, Jordan

    2016-07-01

    The High Altitude Water Cherenkov (HAWC) Gamma-ray Observatory in the high mountains of Mexico was completed in March of 2015 and is now giving us a new view of the TeV sky. HAWC is 15 times more sensitive than the previous generation of wide-field EAS gamma-ray instruments and is able to detect the Crab nebula at >6 σ with each daily transit. In our first year of operation, HAWC has a 5σ detection sensitivity for a source of ~50mCrab. Unlike Imaging Atmospheric Cherenkov Telescopes (IACTs), HAWC operates 24hrs/day with over a 95% on-time and observes the entire overhead sky (~2sr). HAWC's peak energy sensitivity is 2-10 TeV which is ~10x higher than IACTs such as VERITAS and HESS, which makes their observations quite complementary. This talk will present results from the first year of HAWC data including our study of the galactic plane including new sources not yet detected by IACTs as well as spectra and morphology of bright sources. In addition, results of our monitoring of transient AGN will be presented.

  12. Ten-year results of quality assurance in radiotherapy chart round

    PubMed Central

    2013-01-01

    Background The Royal Australian and New Zealand College of Radiologists (RANZCR) initiated a unique instrument to audit the quality of patient notes and radiotherapy prescriptions. We present our experience collected over ten years from the use of the RANZCR audit instrument. Methods In this study, the results of data collected prospectively from January 1999 to June 2009 through the audit instrument were assessed. Radiotherapy chart rounds were held weekly in the uro-oncology tumour stream and real time feedback was provided. Electronic medical records were retrospectively assessed in September 2009 to see if any omissions were subsequently corrected. Results In total 2597 patients were audited. One hundred and thirty seven (5%) patients had one hundred and ninety nine omissions in documentation or radiotherapy prescription. In 79% of chart rounds no omissions were found at all, in 12% of chart rounds one omission was found and in 9% of chart rounds two or more omissions were found. Out of 199 omissions, 95% were of record keeping and 2% were omissions in the treatment prescription. Of omissions, 152 (76%) were unfiled investigation results of which 77 (51%) were subsequently corrected. Conclusions Real-time audit with feedback is an effective tool in assessing the standards of radiotherapy documentation in our department, and also probably contributed to the high level of attentiveness. A large proportion of omissions were investigation results, which highlights the need for an improved system of retrieval of investigation results in the radiation oncology department. PMID:23617328

  13. Peginterferon beta-1a in multiple sclerosis: 2-year results from ADVANCE

    PubMed Central

    Arnold, Douglas L; Balcer, Laura J; Boyko, Alexey A; Pelletier, Jean; Liu, Shifang; Zhu, Ying; Seddighzadeh, Ali; Hung, Serena; Deykin, Aaron; Sheikh, Sarah I; Calabresi, Peter A

    2015-01-01

    Objective: To evaluate the efficacy and safety of subcutaneous peginterferon beta-1a over 2 years in patients with relapsing–remitting multiple sclerosis in the ADVANCE study. Methods: Patients were randomized to placebo or 125 µg peginterferon beta-1a every 2 or 4 weeks. For Year 2 (Y2), patients originally randomized to placebo were re-randomized to peginterferon beta-1a every 2 weeks or every 4 weeks. Patients randomized to peginterferon beta-1a in Year 1 (Y1) remained on the same dosing regimen in Y2. Results: Compared with Y1, annualized relapse rate (ARR) was further reduced in Y2 with every 2 week dosing (Y1: 0.230 [95% CI 0.183–0.291], Y2: 0.178 [0.136–0.233]) and maintained with every 4 week dosing (Y1: 0.286 [0.231–0.355], Y2: 0.291 [0.231–0.368]). Patients starting peginterferon beta-1a from Y1 displayed improved efficacy versus patients initially assigned placebo, with reductions in ARR (every 2 weeks: 37%, p<0.0001; every 4 weeks: 17%, p=0.0906), risk of relapse (every 2 weeks: 39%, p<0.0001; every 4 weeks: 19%, p=0.0465), 12-week disability progression (every 2 weeks: 33%, p=0.0257; every 4 weeks: 25%, p=0.0960), and 24-week disability progression (every 2 weeks: 41%, p=0.0137; every 4 weeks: 9%, p=0.6243). Over 2 years, greater reductions were observed with every 2 week versus every 4 week dosing for all endpoints and peginterferon beta-1a was well tolerated. Conclusions: Peginterferon beta-1a efficacy is maintained beyond 1 year, with greater effects observed with every 2 week versus every 4 week dosing, and a similar safety profile to Y1. Clinicaltrials.gov Registration Number: NCT00906399. PMID:25432952

  14. Twenty-Year Experience of Heart Transplantation: Early and Long-Term Results

    PubMed Central

    Lee, Jae-Hong; Yeom, Sang Yoon; Hwang, Ho Young; Choi, Jae-Woong; Cho, Hyun-Jai; Lee, Hae-Young; Huh, Jae-Hak; Kim, Ki-Bong

    2016-01-01

    Background We evaluated early and long-term results after heart transplantation (HTPL). Methods One hundred five consecutive patients (male:female=80:25) who underwent HTPL between 1994 and 2013 were enrolled. Based on the changes in immunosuppressive regimen, the study patients were divided into two groups. Early and long-term clinical outcomes were evaluated and compared between the patients who underwent HTPL before (group E, n=41) and after July 2009 (group L, n=64). The group L patients were older (p<0.001), had higher incidence of hypertension (p=0.001) and chronic kidney disease (p<0.001), and more frequently needed preoperative mechanical ventilation (p=0.027) and mechanical circulatory support (p=0.014) than the group E patients. Results Overall operative mortality was 3.8%, and postoperative morbidities included acute kidney injury (n=31), respiratory complications (n=16), reoperation for bleeding (n=15) and wound complications (n=10). There were no significant differences in early results except acute kidney injury between group E and group L patients. Overall survival rates at 1, 5, and 10 years were 83.8%, 67.7%, and 54.9%, respectively, with no significant difference between the two patient groups. Rejection-free rates at 1 and 5 years were 63.0% and 59.7%, respectively; rates were significantly higher in group L than in group E (p<0.001). Conclusion Despite increased preoperative comorbidities, group L patients showed similar early and long-term outcomes and significantly higher rejection-free rates when compared with group E patients. PMID:27525232

  15. Fourteen years follow up after Lisfranc fracture-dislocation: functional and radiological results.

    PubMed

    Marín-Peña, Oliver R; Viloria Recio, Fernando; Sanz Gómez, Tomas; Larrainzar Garijo, Ricardo

    2012-12-01

    Injuries to the Lisfranc joint have a high potential for chronic disability. Posttraumatic arthritis remains the most common complication but not all patients who develop degenerative radiographic changes are symptomatic. A cohort of 32 patients with a Lisfranc fracture dislocation was reviewed. Initial reduction and secondary displacement were measured by the Myerson scale. Radiographic evidence of osteoarthritis (OA) was also investigated. Long-term radiographical data were classified as good, fair or poor results. Functional outcome was measured using several different scales. Mean follow up was 14 years. Seventeen patients with anatomic close reduction but instability were treated with closed reduction and K-wire fixation followed by cast immobilisation. Eight patients with stable anatomic close reduction were treated with closed reduction and cast. Seven patients with unacceptable closed reduction were treated with open reduction and K-wire stabilisation. The analysis of radiological long-term data showed 15 patients with good results, 8 with fair results and 9 with poor results. Final mean AOFAS score was 91.7/100. There was no statistically significant difference between overall PFS scores and different type of treatment, Hardcastle long-term radiological scores or Hardcastle type of fracture (p >0.05). Overall, there was a poor association between the extent of radiological arthritis and clinical scores. We advocate that for the evaluation of long-term outcome of these injuries functional parameters should be the focus of assessment, instead of radiological changes. PMID:23622999

  16. Comparison of wear and clinical performance between amalgam, composite and open sandwich restorations: 2-year results.

    PubMed

    Sachdeo, A; Gray, Gordon B; Sulieman, M A; Jagger, Daryll C

    2004-03-01

    There has been some disquiet over the use of mercury containing restorative materials. The most commonly used alternative is composite resin but this has the potential disadvantage associated with wear and marginal leakage, which in turn, has proven to result in secondary caries and sensitivity. To overcome the shortcomings of a directly placed composite restoration, the glass-ionomer/composite open sandwich technique was introduced followed by the subsequent introduction of compomer systems. The aims of this study were to evaluate the wear and clinical performance of a control group of amalgam restorations compared with that of a group of posterior composite resin restorations fillings and a group of compomer/composite open sandwich restorations placed by a single general dental practitioner. The duration of the study was 2 years. One hundred and thirty three (71.4%) patients were successfully recalled and the wear and clinical performance of each restoration after 6, 12 and 24 months was measured, indirectly. There was no statistically significant difference recorded between the groups at 6 months or 1 year (p > 0.05). However, at the end of the 2-year study, there was a significantly lower rate of wear recorded for the control amalgam restorations compared with other two groups (p = 0.033). There was no statistically significant difference in wear recorded between the two groups of tooth-coloured restorations (p > 0.05). With regards to clinical performance of the restorations, occlusal and proximal contacts in each group of restoration remained satisfactory throughout the study. PMID:15058177

  17. Gamma Knife Radiosurgery for Patients With Nonfunctioning Pituitary Adenomas: Results From a 15-Year Experience

    SciTech Connect

    Pollock, Bruce E. Cochran, Joseph; Natt, Neena; Brown, Paul D.; Erickson, Dana; Link, Michael J.; Garces, Yolanda I.; Foote, Robert L.; Stafford, Scott L.; Schomberg, Paula J.

    2008-04-01

    Purpose: To evaluate the efficacy and complications of stereotactic radiosurgery for patients with nonfunctioning pituitary adenomas (NFA). Methods and Materials: This was a retrospective review of 62 patients with NFA undergoing radiosurgery between 1992 and 2004, of whom 59 (95%) underwent prior tumor resection. The median treatment volume was 4.0 cm{sup 3} (range, 0.8-12.9). The median treatment dose to the tumor margin was 16 Gy (range, 11-20). The median maximum point dose to the optic apparatus was 9.5 Gy (range, 5.0-12.6). The median follow-up period after radiosurgery was 64 months (range, 23-161). Results: Tumor size decreased for 37 patients (60%) and remained unchanged for 23 patients (37%). Two patients (3%) had tumor growth outside the prescribed treatment volume and required additional treatment (fractionated radiation therapy, n = 1; repeat radiosurgery, n 1). Tumor growth control was 95% at 3 and 7 years after radiosurgery. Eleven (27%) of 41 patients with normal (n = 30) or partial (n = 11) anterior pituitary function before radiosurgery developed new deficits at a median of 24 months after radiosurgery. The risk of developing new anterior pituitary deficits at 5 years was 32%. The 5-year risk of developing new anterior pituitary deficits was 18% for patients with a tumor volume of {<=}4.0 cm{sup 3} compared with 58% for patients with a tumor volume >4.0 cm{sup 3} (risk ratio 4.5; 95% confidence interval = 1.3-14.9, p = 0.02). No patient had a decline in visual function. Conclusions: Stereotactic radiosurgery is effective in the management of patients with residual or recurrent NFA, although longer follow-up is needed to evaluate long-term outcomes. The primary complication is hypopituitarism, and the risk of developing new anterior pituitary deficits correlates with the size of the irradiated tumor.

  18. New Community Education Program on Oceans and Global Climate Change: Results from Our Pilot Year

    NASA Astrophysics Data System (ADS)

    Bruno, B. C.; Wiener, C.

    2010-12-01

    evaluation results from the first year and discuss how our program has been informed by this feedback.

  19. Nine-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Final Maps and Results

    NASA Technical Reports Server (NTRS)

    Bennett, C. L.; Larson, D.; Weiland, J. L.; Jaorsik, N.; Hinshaw, G.; Odegard, N.; Smith, K. M.; Hill, R. S.; Gold, B.; Halpern, M; Komatsu, E.; Nolta, M. R.; Page, L.; Spergel, D. N.; Wollack, E.; Dunkley, J.; Kogut, A.; Limon,, M.; Meyer, S. S.; Tucker, G. S.; Wright, E. L.

    2013-01-01

    We present the final nine-year maps and basic results from the Wilkinson Microwave Anisotropy Probe (WMAP) mission. The full nine-year analysis of the time-ordered data provides updated characterizations and calibrations of the experiment. We also provide new nine-year full sky temperature maps that were processed to reduce the asymmetry of the effective beams. Temperature and polarization sky maps are examined to separate cosmic microwave background (CMB) anisotropy from foreground emission, and both types of signals are analyzed in detail.We provide new point source catalogs as well as new diffuse and point source foreground masks. An updated template-removal process is used for cosmological analysis; new foreground fits are performed, and new foreground reduced are presented.We nowimplement an optimal C(exp -1)1 weighting to compute the temperature angular power spectrum. The WMAP mission has resulted in a highly constrained Lambda-CDM cosmological model with precise and accurate parameters in agreement with a host of other cosmological measurements. When WMAP data are combined with finer scale CMB, baryon acoustic oscillation, and Hubble constant measurements, we find that big bang nucleosynthesis is well supported and there is no compelling evidence for a non-standard number of neutrino species (N(sub eff) = 3.84 +/- 0.40). The model fit also implies that the age of the universe is (sub 0) = 13.772 +/- 0.059 Gyr, and the fit Hubble constant is H(sub 0) = 69.32 +/- 0.80 km/s/ Mpc. Inflation is also supported: the fluctuations are adiabatic, with Gaussian random phases; the detection of a deviation of the scalar spectral index from unity, reported earlier by the WMAP team, now has high statistical significance (n(sub s) = 0.9608+/-0.0080); and the universe is close to flat/Euclidean (Omega = -0.0027+0.0039/-0.0038). Overall, the WMAP mission has resulted in a reduction of the cosmological parameter volume by a factor of 68,000 for the standard six

  20. Human factors in aircraft incidents - Results of a 7-year study (Andre Allard Memorial Lecture)

    NASA Technical Reports Server (NTRS)

    Billings, C. E.; Reynard, W. D.

    1984-01-01

    It is pointed out that nearly all fatal aircraft accidents are preventable, and that most such accidents are due to human error. The present discussion is concerned with the results of a seven-year study of the data collected by the NASA Aviation Safety Reporting System (ASRS). The Aviation Safety Reporting System was designed to stimulate as large a flow as possible of information regarding errors and operational problems in the conduct of air operations. It was implemented in April, 1976. In the following 7.5 years, 35,000 reports have been received from pilots, controllers, and the armed forces. Human errors are found in more than 80 percent of these reports. Attention is given to the types of events reported, possible causal factors in incidents, the relationship of incidents and accidents, and sources of error in the data. ASRS reports include sufficient detail to permit authorities to institute changes in the national aviation system designed to minimize the likelihood of human error, and to insulate the system against the effects of errors.

  1. Trends and predictors of asthma costs: results from a 10-year longitudinal study.

    PubMed

    Tan, Ngiap Chuan; Nguyen, Hai V; Lye, Weng Kit; Sankari, Usha; Nadkarni, Nivedita V

    2016-03-01

    Research on asthma costs often focuses on estimating average asthma costs. Trends in asthma costs and patterns of medication use, especially for those who have been followed up and under treatment, have received much less attention. This study's objective was to document asthma costs over time for asthma patients who are enrolled in an asthma care programme in Singapore and to identify its predictors, using a 10-year longitudinal dataset.The study population comprised different cohorts of 939 asthma patients entering the programme at different times during 2004-2013. Average asthma costs were estimated and the trends over time examined graphically, within and across patient cohorts. Regression analyses were conducted to examine cost predictors, with a focus on the relationship between risk factors at programme enrolment and subsequent asthma costs.The results indicate that 10-year average annual asthma cost was GBP 341 per patient. The main drivers of costs were asthma medications and consultation fees. Use of combined inhaled corticosteroid/long-acting β-agonist medications increased over time, but this was accompanied by declines in controller drug use, doctor visits and total asthma drug costs. Obesity, smoking and asthma severity were the main predictors of subsequent asthma costs, especially for females. PMID:26647437

  2. OzDES multifibre spectroscopy for the Dark Energy Survey: First-year operation and results

    SciTech Connect

    Yuan, Fang

    2015-07-29

    The Australian Dark Energy Survey (OzDES) is a five-year, 100-night, spectroscopic survey on the Anglo-Australian Telescope, whose primary aim is to measure redshifts of approximately 2500 Type Ia supernovae host galaxies over the redshift range 0.1 < z < 1.2, and derive reverberation-mapped black hole masses for approximately 500 active galactic nuclei and quasars over 0.3 < z < 4.5. This treasure trove of data forms a major part of the spectroscopic follow-up for the Dark Energy Survey for which we are also targeting cluster galaxies, radio galaxies, strong lenses, and unidentified transients, as well as measuring luminous red galaxies and emission line galaxies to help calibrate photometric redshifts. Here, we present an overview of the OzDES programme and our first-year results. Between 2012 December and 2013 December, we observed over 10 000 objects and measured more than 6 000 redshifts. Our strategy of retargeting faint objects across many observing runs has allowed us to measure redshifts for galaxies as faint as mr = 25 mag. We outline our target selection and observing strategy, quantify the redshift success rate for different types of targets, and discuss the implications for our main science goals. In conclusion, we highlight a few interesting objects as examples of the fortuitous yet not totally unexpected discoveries that can come from such a large spectroscopic survey.

  3. Fourteen Thousand Solar Systems and Growing: Results From the Starchitect Online Game at One Year

    NASA Astrophysics Data System (ADS)

    Harold, J. B.

    2015-12-01

    Starchitect (www.starchitect.net) is an online, end-to-end stellar and planetary evolution game designed to teach players about a variety of astronomy and planetary topics. Supported by NASA and NSF, and developed at the National Center for Interactive Learning at the Space Science Institute, the game uses the "sporadic play" model of games such as Farmville, where players might only take actions a few times a day, but continue playing for months. This framework is a natural fit for teaching about the evolution of stars and planets. Starchitect's systems evolve at a million years a minute, so that while massive stars will supernova almost immediately, lower mass stars like our sun will live for weeks of game time, possibly evolving life before passing through a red giant stage and ending their lives as white dwarfs. The game has now been live for over a year, playable both on Facebook and externally, and over 14,000 solar systems have been created by over 11,000 players. Since the game itself is heavily instrumented we now have access to a wealth of data that can be used to examine how people are playing the game and what tasks they are successfully engaging with. Through an embedded quiz game we are even in the position to assess the prior knowledge of our audience and execute pre/post assessments tied to game play. This paper will briefly describe the game and its educational strategies, then summarize some of our current results.

  4. Simulation of natural corrosion by vapor hydration test: seven-year results

    SciTech Connect

    Luo, J.S.; Ebert, W.L.; Mazer, J.J.; Bates, J.K.

    1996-12-31

    We have investigated the alteration behavior of synthetic basalt and SRL 165 borosilicate waste glasses that had been reacted in water vapor at 70 {degrees}C for time periods up to seven years. The nature and extent of corrosion of glasses have been determined by characterizing the reacted glass surface with optical microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive x-ray spectroscopy (EDS). Alteration in 70 {degrees}C laboratory tests was compared to that which occurs at 150-200 {degrees}C and also with Hawaiian basaltic glasses of 480 to 750 year old subaerially altered in nature. Synthetic basalt and waste glasses, both containing about 50 percent wt SiO{sub 2} were found to react with water vapor to form an amorphous hydrated gel that contained small amounts of clay, nearly identical to palagonite layers formed on naturally altered basaltic glass. This result implies that the corrosion reaction in nature can be simulated with a vapor hydration test. These tests also provide a means for measuring the corrosion kinetics, which are difficult to determine by studying natural samples because alteration layers have often spelled off the samples and we have only limited knowledge of the conditions under which alteration occurred.

  5. OzDES multifibre spectroscopy for the Dark Energy Survey: First-year operation and results

    DOE PAGESBeta

    Yuan, Fang

    2015-07-29

    The Australian Dark Energy Survey (OzDES) is a five-year, 100-night, spectroscopic survey on the Anglo-Australian Telescope, whose primary aim is to measure redshifts of approximately 2500 Type Ia supernovae host galaxies over the redshift range 0.1 < z < 1.2, and derive reverberation-mapped black hole masses for approximately 500 active galactic nuclei and quasars over 0.3 < z < 4.5. This treasure trove of data forms a major part of the spectroscopic follow-up for the Dark Energy Survey for which we are also targeting cluster galaxies, radio galaxies, strong lenses, and unidentified transients, as well as measuring luminous red galaxiesmore » and emission line galaxies to help calibrate photometric redshifts. Here, we present an overview of the OzDES programme and our first-year results. Between 2012 December and 2013 December, we observed over 10 000 objects and measured more than 6 000 redshifts. Our strategy of retargeting faint objects across many observing runs has allowed us to measure redshifts for galaxies as faint as mr = 25 mag. We outline our target selection and observing strategy, quantify the redshift success rate for different types of targets, and discuss the implications for our main science goals. In conclusion, we highlight a few interesting objects as examples of the fortuitous yet not totally unexpected discoveries that can come from such a large spectroscopic survey.« less

  6. [Transfer of cardiac catheterisation from a paediatric to an adult cardiological centre: results at 3 years].

    PubMed

    Agnoletti, G; Boudjemline, Y; Ladouceur, M; Iserin, L

    2007-05-01

    The advances of surgical and interventional treatment of congenital heart diseases have allowed a large number of patients with congenital heart disease to reach adult age. This population involves almost 0.3/1000 of total population in West Europe and North America and can be estimated around 200000 patients in France. Patients with operated Tetralogy of Fallot, benign forms of pulmonary atresia with ventricular septal defect, simple or complex transposition of the great arteries usually survive beyond childhood. These patients can need repeated interventions to treat lesions of native or reconstructed pulmonary arteries and/or aortic arch, to occlude residual shunts, to treat pulmonary incompetence. More complex heart diseases such as single ventricle, rarely allow survival until the adult age. The majority of these patients undergo heart transplant, often made difficult by multiple cardiac surgeries, anomalies of pulmonary arteries, chronic cyanosis, aorto-pulmonary shunts. Patients with relatively simple or complex congenital heart diseases need to be followed-up in specialized units, like those created more than twenty years ago in the United States, Canada, and United Kingdom. Interventional cardiac catheterisation play a major role in the management of this population. The results of 3 years of activity in a new centre treating GUCH patients are illustrated. PMID:17646764

  7. Biofilm formation and control in a simulated spacecraft water system - Three year results

    NASA Technical Reports Server (NTRS)

    Schultz, John R.; Flanagan, David T.; Bruce, Rebekah J.; Mudgett, Paul D.; Carr, Sandra E.; Rutz, Jeffrey A.; Huls, M. H.; Sauer, Richard L.; Pierson, Duane L.

    1992-01-01

    Two simulated spacecraft water systems are being used to evaluate the effectiveness of iodine for controlling microbial contamination within such systems. An iodine concentration of about 2.0 mg/L is maintained in one system by passing ultrapure water through an iodinated ion exchange resin. Stainless steel coupons with electropolished and mechanically-polished sides are being used to monitor biofilm formation. Results after three years of operation show a single episode of significant bacterial growth in the iodinated system when the iodine level dropped to 1.9 mg/L. This growth was apparently controlled by replacing the iodinated ion exchange resin, thereby increasing the iodine level. The second batch of resin has remained effective in controlling microbial growth down to an iodine level of 1.0 mg/L. SEM indicates that the iodine has impeded but may have not completely eliminated the formation of biofilm. Metals analyses reveal some corrosion in the iodinated system after 3 years of continuous exposure. Significant microbial contamination has been present continuously in a parallel noniodinated system since the third week of operation.

  8. ATS-5 solar cell experiment results after one year in synchronous orbit

    NASA Technical Reports Server (NTRS)

    Anspaugh, B. E.

    1972-01-01

    The results of the ATS-5 solar cell experiment after one year in synchronous orbit are reported. A partial failure in the experimental electronics package has caused a loss of data from half the 80 experimental solar cells. Procedures for extracting data due to a partial spacecraft failure are described and discussed. Data from the remaining 40 solar cells, including 15 mounted on a thin flexible structure are analyzed. Data are corrected to a solar intensity of 140 mW/sq cm and a temperature of 25 C. It was found that after one year in synchronous orbit: (1) cells with 1.52-mm-thick coverslides did not show a clear-cut advantage over those with 0.15-mm coverslides, (2) cells with solderless grid lines are degrading at the same rate as are cells with solder-dipped grid lines, (3) cells not quite completely covered with coverslides suffered a large power loss in comparison to cells fully covered, (4) no clear-cut advantage of 10-cm cells over 2-cm cells has yet been observed, (5) cells mounted on the flexible panel with relatively little backshielding did not degrade any faster than those with substantial backshielding, and (6) the flight data in large part confirms the adequacy of the ground-based techniques used in our preflight radiation test program.

  9. Results from the first two years of the INTEGRAL Spiral Arms Monitoring Program

    NASA Astrophysics Data System (ADS)

    Bodaghee, Arash; Spetzer, Keri

    2014-08-01

    We describe the scientific objectives and main highlights from the first 2 years of an INTEGRAL "Key Program" consisting of high-cadence monitoring of the inner spiral arms of the Galaxy paired with ToO observations of new transients with XMM-Newton and Swift. The INTEGRAL Spiral Arms (ISA) program (25.6 ks per spacecraft revolution during visibility periods, for a total of 1.2 Ms per year since 2012) complements the successful Galactic Bulge (GB) program by extending the monitored region of the Galaxy to the Inner Perseus/Norma Arm tangents on one side of the GB, and the Scutum/Sagittarius Arms on the other. These fields feature a high density of obscured high-mass X-ray binaries (HMXBs), including Supergiant Fast X-ray Transients (SFXTs), as well as other hard X-ray emitting sources (e.g. microquasars, low-mass X-ray binaries, and magnetars) that INTEGRAL is well-suited to finding thanks to its large field of view and angular resolution at high energies even in crowded regions of the sky. Mosaic images and source light curves in 2 energy bands for ISGRI and JEM-X are being provided to the community permitting rapid dissemination of results (http://isa.gcsu.edu) which enable prompt follow-up of interesting events. The ISA project represents the cornerstone of our ongoing study of transient and variable hard X-ray populations in the Milky Way.

  10. OzDES multifibre spectroscopy for the Dark Energy Survey: first-year operation and results

    NASA Astrophysics Data System (ADS)

    Yuan, Fang; Lidman, C.; Davis, T. M.; Childress, M.; Abdalla, F. B.; Banerji, M.; Buckley-Geer, E.; Carnero Rosell, A.; Carollo, D.; Castander, F. J.; D'Andrea, C. B.; Diehl, H. T.; Cunha, C. E.; Foley, R. J.; Frieman, J.; Glazebrook, K.; Gschwend, J.; Hinton, S.; Jouvel, S.; Kessler, R.; Kim, A. G.; King, A. L.; Kuehn, K.; Kuhlmann, S.; Lewis, G. F.; Lin, H.; Martini, P.; McMahon, R. G.; Mould, J.; Nichol, R. C.; Norris, R. P.; O'Neill, C. R.; Ostrovski, F.; Papadopoulos, A.; Parkinson, D.; Reed, S.; Romer, A. K.; Rooney, P. J.; Rozo, E.; Rykoff, E. S.; Sako, M.; Scalzo, R.; Schmidt, B. P.; Scolnic, D.; Seymour, N.; Sharp, R.; Sobreira, F.; Sullivan, M.; Thomas, R. C.; Tucker, D.; Uddin, S. A.; Wechsler, R. H.; Wester, W.; Wilcox, H.; Zhang, B.; Abbott, T.; Allam, S.; Bauer, A. H.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Burke, D. L.; Carrasco Kind, M.; Covarrubias, R.; Crocce, M.; da Costa, L. N.; DePoy, D. L.; Desai, S.; Doel, P.; Eifler, T. F.; Evrard, A. E.; Fausti Neto, A.; Flaugher, B.; Fosalba, P.; Gaztanaga, E.; Gerdes, D.; Gruen, D.; Gruendl, R. A.; Honscheid, K.; James, D.; Kuropatkin, N.; Lahav, O.; Li, T. S.; Maia, M. A. G.; Makler, M.; Marshall, J.; Miller, C. J.; Miquel, R.; Ogando, R.; Plazas, A. A.; Roodman, A.; Sanchez, E.; Scarpine, V.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, R. C.; Soares-Santos, M.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thaler, J.; Walker, A. R.

    2015-09-01

    The Australian Dark Energy Survey (OzDES) is a five-year, 100-night, spectroscopic survey on the Anglo-Australian Telescope, whose primary aim is to measure redshifts of approximately 2500 Type Ia supernovae host galaxies over the redshift range 0.1 < z < 1.2, and derive reverberation-mapped black hole masses for approximately 500 active galactic nuclei and quasars over 0.3 < z < 4.5. This treasure trove of data forms a major part of the spectroscopic follow-up for the Dark Energy Survey for which we are also targeting cluster galaxies, radio galaxies, strong lenses, and unidentified transients, as well as measuring luminous red galaxies and emission line galaxies to help calibrate photometric redshifts. Here, we present an overview of the OzDES programme and our first-year results. Between 2012 December and 2013 December, we observed over 10 000 objects and measured more than 6 000 redshifts. Our strategy of retargeting faint objects across many observing runs has allowed us to measure redshifts for galaxies as faint as mr = 25 mag. We outline our target selection and observing strategy, quantify the redshift success rate for different types of targets, and discuss the implications for our main science goals. Finally, we highlight a few interesting objects as examples of the fortuitous yet not totally unexpected discoveries that can come from such a large spectroscopic survey.

  11. Early intervention and prevention of anxiety disorders in children: results at 2-year follow-up.

    PubMed

    Dadds, M R; Holland, D E; Laurens, K R; Mullins, M; Barrett, P M; Spence, S H

    1999-02-01

    The Queensland Early Intervention and Prevention of Anxiety Project evaluated a child- and family-focused group intervention for preventing anxiety problems in children. This article reports on 12- and 24-month follow-up data to previously reported outcomes at posttreatment and at 6-month follow-up. A total of 1,786 7- to 14-year-olds were screened for anxiety problems using teacher nominations and children's self-report. After diagnostic interviews, 128 children were selected and assigned to either a 10-week school-based child- and parent-focused psychosocial intervention or a monitoring group. Both groups showed improvements immediately at postintervention and at 6-month follow-up; the improvement was maintained in the intervention group only reducing the rate of existing anxiety disorder and preventing the onset of new anxiety disorders. At 12 months, the groups converged, but the superiority of the intervention group was evident again at 2-year follow-up. Severity of pretreatment diagnoses, gender, and parental anxiety predicted poor initial response to intervention, whereas pretreatment severity was the only predictor of chronicity at 24 months. Overall, follow-up results show that a brief school-based intervention for children can produce durable reductions in anxiety problems. PMID:10028219

  12. Summary results from the NASA Tech House one year live-in

    NASA Technical Reports Server (NTRS)

    Hamlet, I. L.

    1979-01-01

    The NASA Tech House was designed and constructed at the Langley Research Center, Hampton, Va., to demonstrate and evaluate new technology potentially applicable for conservation of energy and resources and for improvements in safety and security in a single-family residence. All technology items, including solar energy systems and a waste water reuse system, were evaluated under actual living conditions for a one-year period with a family of four living in the house in their normal life style. Results are presented which show overall savings in energy and resources compared to requirements for a defined similar conventional house under the same conditions. Also included are general operational experience and performance data for all the various items and systems of technology incorporated into the house design.

  13. [Results evaluations 3 years after our first experience with the laparoscopic treatment of Hirschsprung disease].

    PubMed

    Polliotto, S; Heinen, F; Andina, G; Korman, R

    2001-04-01

    The laparoscopic approach has been successfully used during the recent last years in pediatric surgery. We describe the first experience in Argentina using laparoscopic surgery in November 4th in 1996, for the treatment of a Hirschsprung disease case. We used the technique of Soave's modified by Georgenson. Details of the surgical procedure are given. Hospitalization time took 5 days and immediated postoperatory cares were well done. Soave-Georgeson technique seems to be a safe and effective possibility for the Hirschsprung disease treatment, and it is completely achieveable by laparoscopy. The present experience does not show advantages in terms of a lower hospitalization time, however it really shows the benefits of laparoscopic surgery, such as post-operatory comfort and better cosmetic results, both highly superior than those obtained with classical surgery. PMID:11480199

  14. Results with the Roseland(®) HAC trapeziometacarpal prosthesis after more than 10 years.

    PubMed

    Semere, A; Vuillerme, N; Corcella, D; Forli, A; Moutet, F

    2015-04-01

    The Roseland(®) hydroxyapatite-coated prosthesis is a total trapeziometacarpal joint prosthesis used for the surgical treatment of thumb basal joint arthritis. The aim of this retrospective study was to evaluate its long-term outcomes. Fifty-one patients (64 thumbs) underwent trapeziometacarpal joint replacement with this prosthesis. The mean follow-up was 12.5 years. Survival rate of the prosthesis was 91%. There was either no pain or only occasional pain in 91% of cases. The mean QuickDASH score was 27.6. Abnormal radiographic findings were present in 70% of cases. Since they were often asymptomatic, no further treatment was carried out. Complications were common (25%) and occurred early on but could often be treated without surgery. The long-term results with the Roseland(®) HAC prosthesis are satisfactory in terms of pain relief and function. However, the high complication rate is a major concern. PMID:25769771

  15. DOE (Department of Energy) radiological calibrations intercomparison program: Results of fiscal year 1989

    SciTech Connect

    Murphy, M.K.; McDonald, J.C.

    1990-10-01

    In Fiscal Year 1989, the instrument sets were used to intercompare calibration fields associated with {sup 137}Cs, {sup 60}Co, {sup 90}Sr, {sup 241}AmBe and {sup 252}Cf. The results of the delivered-to-measured exposure rate and absorbed dose rate ratios were 1.00 {plus minus} 0.01 for photon measurements, 1.01 {plus minus} 0.01 for TLD measurements, 1.00 {plus minus} 0.02 for neutron measurements and a ratio of 1.03 for beta measurements. From the excellent agreement shown here it is evident that the radiological calibration intercomparison program is achieving its objective. 12 refs., 3 figs., 8 tabs.

  16. Observing Global Ocean Circulation From Space: The First Year's Results From the TOPEX/POSEIDON Mission

    NASA Technical Reports Server (NTRS)

    Fu, L. -L.

    1993-01-01

    The joint U.S./France TOPEX/Poseidon satellite was launched on August 10, 1992, and became operational 42 days later. The major goal of the mission is to use a radar altimeter system for making precise measurements of the height of the sea surface for the study of the dynamics of large-scale ocean circulation, which is a key to understanding global climate change. Additionally, the data are used for studying ocean tides and marine geophysics. The radar altimeter also measures wave height and wind speed. The mission is being conducted to optimize the sea surface height measurements for a minimum of three years. The primary objective of the first six months of the mission was to calibrate and validate the mission's measurements. The verification results indicate that all the measurement objectives have been met...

  17. [Comparison of the results of coronary angioplasty and stenting during one year following surgery].

    PubMed

    Simonenko, V B; Seĭdov, V G; Zakharov, S V; Evsiukov, V V; Liubchuk, I V

    2007-01-01

    The purpose of the study was to compare long-term results of angioplasty and coronary arterial stenting (CAS) depending on the initial degree of coronary arterial (CA) lesion according to morphological stenosis classification, as well as to evaluate the influence of re-stenosis on myocardial contractility dynamics, anginal recurrence rate, and exercise tolerance. The subjects, 228 men after angioplasty and 184 men after CAS with wire stents without drug coating, were included in the study between 1989 and 2005. Coronarography was repeated in 358 patients one year after surgery. The patients were divided into two groups. The first group consisted of 161 patients, to who 180 stents were implanted. The second group consisted of 197patients, in who 226 angioplasty procedures were performed. Data were processed using standard variational statistical methods, i.e. the calculation of mean values and standard deviation. Statistical calculations were carried out using Analysis ToolPak- VBA software of Microsoft Excel 2000. The study found that one year after either intervention the number of patients without anginal symptoms fell significantly compared with this number during the in-hospital period. In group 2 the frequency of restenosis was higher and the number of patients with anginal symptoms was significantly bigger than in group 1; the number of asymptomatic patients was significantly bigger in group 1. Initial morphological characteristics of CA lesion had a significant effect on the long-term frequency of restenosis following endovascular treatment. Restenosis was 2 to 2.5 times more frequent in patients with C type CA lesion vs. patients with A type regardless the method of endovascular intervention. The results of the study demonstrate the importance of taking into account initial morphological characteristics of CA lesion; CAS is more preferable than angioplasty, especially in patients with C type CA lesion. PMID:17520881

  18. Streptococcus Endophthalmitis Outbreak after Intravitreal Injection of Bevacizumab: One-year Outcomes and Investigative Results

    PubMed Central

    Goldberg, Roger A.; Flynn, Harry W.; Miller, Darlene; Gonzalez, Serafin; Isom, Ryan F.

    2013-01-01

    Purpose To report the one-year clinical outcomes of an outbreak of Streptococcus endophthalmitis after intravitreal injection of bevacizumab, including visual acuity outcomes, microbiological testing and compound pharmacy investigations by the Food and Drug Administration (FDA). Design Retrospective consecutive case series. Participants 12 eyes of 12 patients who developed endophthalmitis after receiving intravitreal bevacizumab prepared by a single compounding pharmacy. Methods Medical records of patients were reviewed; phenotypic and DNA analyses were performed on microbes cultured from patients and from unused syringes. An inspection report by the FDA based on site-visits to the pharmacy that prepared the bevacizumab syringes was summarized. Main Outcome Measures Visual acuity, interventions received, time-to-intervention; microbiological consistency; FDA inspection findings. Results Between July 5 and July 8, 2011, 12 patients developed endophthalmitis after intravitreal bevacizumab from syringes prepared by a single compounding pharmacy. All patients received initial vitreous tap and injection, and eight (67%) subsequently underwent pars plana vitrectomy (PPV). After twelve months follow-up, outcomes have been poor: 7 patients (58%) required evisceration or enucleation, and only one patient regained pre-injection visual acuity. Molecular testing using real time polymerase chain reaction, partial sequencing of the groEL gene, and multilocus sequencing of 7 housekeeping genes confirmed the presence of a common strain of Streptococcus mitis/oralis in vitreous specimens and seven unused syringes prepared by the compounding pharmacy at the same time. An FDA investigation of the compounding pharmacy noted deviations from standard sterile technique, inconsistent documentation, and inadequate testing of equipment required for safe preparation of medications. Conclusions In this outbreak of endophthalmitis, outcomes have been generally poor and PPV did not improve

  19. Endovascular stents in children under 1 year of age: acute impact and late results.

    PubMed Central

    Hatai, Y.; Nykanen, D. G.; Williams, W. G.; Freedom, R. M.; Benson, L. N.

    1995-01-01

    OBJECTIVES--To review efficacy and safety of endovascular stent implants in children < 1 year of age with congenital heart lesions. DESIGN--Retrospective study of patients in a tertiary care setting. PATIENTS--26 children (median age of 4.7 months, range 2 days to 1 year) with various vascular obstructive lesions. INTERVENTION--Percutaneous or intraoperative implantation of balloon expandable endovascular stents. RESULTS--Optimal stent placement was obtained in 31 of the 37 deployed implants. Complications resulted primarily from stent malpositioning and one episode of bleeding at a puncture site. Stent implantation in three patients with a restrictive arterial duct allowed for patency and five patients with conduit stenosis had mean (SD) right ventricule to systemic artery pressure ratios falling from 0.99 (0.20) to 0.52 (0.18) (P < 0.05). In 10 patients with pulmonary artery stenosis, the mean vessel diameter increased from 2.8 (0.9) mm to 5.8 (1.4) mm (P << 0.001). No clinical improvement was seen in two patients because of diffuse hypoplasia of the pulmonary vessels. Nine of 10 patients with miscellaneous obstructive lesions improved clinically. Recatheterisation was performed in 19 patients (median 8 months, range 12 days to 28 months) and 11 patients required redilatation (17 stents). CONCLUSIONS--Stent implantation is technically feasible in infants and under specific circumstances may provide an alternative to surgical palliation or avoid reoperation. The long term impact on clinical course, however, involves further interventions directed at stent management. Images PMID:8541180

  20. [Surgical treatment of concomitant strabism in children younger than 15 years. Results 6 weeks after surgery].

    PubMed

    Haugen, O H; Støle, M P

    1995-02-20

    In order to evaluate the short-term results we carried out a retrospective study on 104 children who had been operated on in 1993 for concomitant convergent (n = 74) and divergent (n = 30) strabismus. Six weeks after the operation an alignment within 0-10 delta was achieved in 64% of the convergent children and 44% of the divergent children. When we evaluated the subgroups of children with convergent strabismus we found a postoperative alignment within 0-10 delta in 54% of the patients with strabismus from before six months of age (infantile esotropia), and in 93% of the children in whom the strabismus was present from after two years of age. In the total material we could demonstrate an improvement in binocular function in 17%. Based on a total evaluation we consider that 80% obtained a good postoperative result. We believe that continual, computer-based evaluation of the strabismus patients would be a valuable tool to further improve our results. PMID:7900114

  1. Results of Detailed Hydrologic Characterization Tests—Fiscal and Calendar Year 2005

    SciTech Connect

    Spane, Frank A.; Newcomer, Darrell R.

    2008-02-27

    This report provides the results of detailed hydrologic characterization tests conducted within selected Hanford Site wells during fiscal and calendar year 2005. Detailed characterization tests performed included groundwater-flow characterization, barometric response evaluation, slug tests, in-well vertical groundwater-flow assessments, and a single-well tracer and constant-rate pumping test. Hydraulic property estimates obtained from the detailed hydrologic tests include hydraulic conductivity, transmissivity, specific yield, effective porosity, in-well lateral and vertical groundwater-flow velocity, aquifer groundwater-flow velocity, and depth-distribution profiles of hydraulic conductivity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for a site where detailed well testing was performed. Results obtained from these tests provide hydrologic information that supports the needs of Resource Conservation and Recovery Act waste management area characterization as well as sitewide groundwater monitoring and modeling programs. These results also reduce the uncertainty of groundwater-flow conditions at selected locations on the Hanford Site.

  2. A Five-Year Analysis of MODIS NDVI and NDWI for Rangeland Drought Assessment: Preliminary Results

    NASA Astrophysics Data System (ADS)

    Gu, Y.; Brown, J. F.; Verdin, J. P.; Wardlow, B.

    2006-12-01

    Drought is one of the most costly natural disasters in the United States. Traditionally, drought monitoring has been based on weather station observations, which lack the continuous spatial coverage needed to adequately characterize and monitor detailed spatial patterns of drought conditions. Satellite remote sensing observations can provide a synoptic view of the land and provide a spatial context for measuring drought. A common satellite-based index, the normalized difference vegetation index (NDVI) has a 30-year history of use for vegetation condition monitoring. NDVI is calculated from the visible red and near infrared channels and measures the changes in chlorophyll absorption and reflection in the spongy mesophyll of the vegetation canopy that are reflected in these respective bands. The normalized difference water index (NDWI) is another index, derived from the near-infrared and short wave infrared channels, and reflects changes in both the water content and spongy mesophyll in the vegetation canopy. As a result, the NDWI is influenced by both desiccation and wilting in the vegetation canopy and may be a more sensitive indicator than the NDVI for large- area drought monitoring. The objective of this study was to process and evaluate a 5-year history of 500-meter NDVI and NDWI data derived from the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument and to investigate methods for measuring and monitoring drought in rangeland over the southern plains of the United States. This initial study included: (1) the development of a climatological database for MODIS NDVI and NDWI, (2) a study of the relationship between the NDVI, NDWI, and drought condition over rangeland, (3) the development of a method to provide threshold NDVI/NDWI values under drought conditions based on the 5-year NDVI/NDWI/drought condition analysis, and (4) the investigation of additional vegetation drought information provided by the NDWI versus the NDVI in a 5-year comparison of

  3. Estimation of Energy Savings Resulting From the BestPractices Program, Fiscal Year 2002

    SciTech Connect

    Truett, LF

    2003-09-24

    Within the U.S. Department of Energy (DOE), the Office of Energy Efficiency and Renewable Energy (EERE) has a vision of a future with clean, abundant, reliable, and affordable energy. Within EERE, the Industrial Technologies Program (ITP), formerly the Office of Industrial Technologies, works in partnership with industry to increase energy efficiency, improve environmental performance, and boost productivity. The BestPractices (BP) Program, within ITP, works directly with industries to encourage energy efficiency. The purpose of the BP Program is to improve energy utilization and management practices in the industrial sector. The program targets distinct technology areas, including pumps, process heating, steam, compressed air, motors, and insulation. This targeting is accomplished with a variety of delivery channels, such as computer software, printed publications, Internet-based resources, technical training, technical assessments, and other technical assistance. A team of program evaluators from Oak Ridge National Laboratory (ORNL) was tasked to evaluate the fiscal year 2002 (FY02) energy savings of the program. The ORNL assessment enumerates levels of program activity for technology areas across delivery channels. In addition, several mechanisms that target multiple technology areas--e.g., Plant-wide Assessments (PWAs), the ''Energy Matters'' newsletter, and special events--are also evaluated for their impacts. When possible, the assessment relies on published reports and the Industrial Assessment Center (IAC) database for estimates of energy savings that result from particular actions. Data were also provided by ORNL, Lawrence Berkeley National Laboratory (LBNL) and Project Performance Corporation (PPC), the ITP Clearinghouse at Washington State University, the National Renewable Energy Laboratory (NREL), Energetics Inc., and the Industrial Technologies Program Office. The estimated energy savings in FY02 resulting from activities of the BP Program are almost

  4. The effects of Crew Resource Mangement (CRM) training in airline maintenance: Results following three years' experience

    NASA Technical Reports Server (NTRS)

    Taylor, J. C.; Robertson, M. M.

    1995-01-01

    This report describes three years' evaluation of the effects of one airline's Crew Resources Management (CRM) training operation for maintenance. This evaluation focuses on the post-training attitudes of maintenance managers' and technical support professionals, their reported behaviors, and the safety, efficiency and dependable maintenance performance of their units. The results reveal a strong positive effect of the training. The overall program represents the use of CRM training as a long-term commitment to improving performance through effective communication at all levels in airline maintenance operations. The initial findings described in our previous progress reports are reinforced and elaborated here. The current results benefit from the entire pre-post training survey, which now represents total attendance of all managers and staff professionals. Additionally there are now full results from the two-month, six-month, and 12-month follow-up questionnaires, together with as many as 33 months of post-training performance data, using several indicators. In this present report, we examine participants' attitudes, their reported behaviors following the training, the performance of their work units, and the relationships among these variables. Attitudes include those measured immediately before and after the training as well as participants' attitudes months after their training. Performance includes measures, by work units, of on-time flight departures, on-schedule maintenance releases, occupational and aircraft safety, and efficient labor costs. We report changes in these performance measures following training, as well their relationships with the training participants' attitudes. Highlights of results from this training program include increased safety and improved costs associated with positive attitudes about the use of more assertive communication, and the improved management of stress. Improved on-time performance is also related to those improved

  5. [Cementless total hip arthroplasty--results of 8-year follow-up study].

    PubMed

    Wall, Andrzej; Dragan, Szymon

    2006-01-01

    The subjects of the clinical examinations were 382 patients who from 1994 to 1999 were treated with the method of total cementless arthroplasty. The observation time ranged from 3 to 8 years. In the examined group the secondary cause of degenerative changes was identified in 210 (55%) patients. In the remaining 172 cases (45%) the primary cause of degenerative changes in the hip was diagnosed. Four types of cementless endoprostheses, varied in their construction, structure of their surfaces and material they were made of, were used to carry out the postoperative treatment of the degenerative changes in the hip: Antega, Zweymüller SL PLUS (Endoprosthetic) or Alloclasic type of stem, GSS-CL and PM-Plasmapore. The findings of the clinical investigation made it possible to determine the probability of surviving of an endoprosthesis up to the 8th year after an operation depending on a type of implanted stem, which according to Kaplan-Meier's method, amounted to 0.9603. The results of Harris scale evaluation of the function of the operated joints demonstrated the existence of the relationship between the function and the course of bone osteointegration and growth process. The detailed analysis of the X-ray examinations, and especially of the roentgenometric ones, taking into account stability of the endoprosthesis stem enabled to distinguish two stages of the clinical and roentgenological changes: the early stage (up to 6 months after an operation) characterised by settling and micromotions of the stem and the late stage (starting 6-9 months after an operation) with slowly gradual increasing of the function and holding back of stem settling. PMID:17017478

  6. Development and first year of results from the Heliometer of Observatório Nacional

    NASA Astrophysics Data System (ADS)

    Andrei, Alexandre H.; D'Ávila, Victor A.; Neto, Eugânio Reis; Penna, Jucira L.; Boscardin, Sérgio C.; Coletti, Alissandro; Oliveira, Luiz C.; Sigismondi, Costantino

    2013-07-01

    Recent research on global climate changes points to three distinct sources of climate disturbance: anthropogenic; natural changes in the oceans and atmosphere; and irregularities in the solar cycles. One of the most direct ways to survey an exogenous component of the climatic variability is through the measurement of variations in the diameter and shape of the solar disk. At Observatório Nacional/MCTI, Rio de Janeiro, after several years of diameter observation using a CCD Solar Astrolabe, these measurements are now performed by a state-of-the-art Solar Heliometer. The heliometric method is one of the most successful techniques to measure small variations of angles. Its principle has been used for the latest space borne astrometric missions, aiming to milli-arcsecond precision. The success of this method relies in the fact that it minimizes the dependence of angular measurements to the thermal and mechanical stability of the instrument. However in the classic heliometer the objective is split into two halves to which is applied a linear displacement along the cut, thus still leaving room for a residual dependence with the focus, due to non-concentricity of the beams of the two images. The focus variation, as well as the effects brought by the large temperature variations during solar observations, was tackled in the Solar Heliometer by having all optical elements and their niches made on CCZ, and the telescope tube on carbon fiber, both materials of negligible thermal coefficient. Additionally, the measures are made perpendicular to the separation direction and the plate scale can be known at every time from the solar motion itself. We present the results from the first year of measurements, in special exploring the upheaval of solar activity on late 2011.

  7. Stereopsis Results at 4.5 Years of Age in the Infant Aphakia Treatment Study

    PubMed Central

    Hartmann, E. Eugenie; Stout, Ann U.; Lynn, Michael J.; Yen, Kimberly G.; Kruger, Stacey J.; Lambert, Scott R.

    2014-01-01

    Purpose To determine whether stereopsis of infants treated for monocular cataracts varies with the type of optical correction used. Design Randomized prospective clinical trial Methods The Infant Aphakia Treatment Study randomized 114 patients with unilateral cataracts at age 1 to 7 months to either primary intraocular lens (IOL) or contact lens correction. At 4.5 years of age a masked examiner assessed stereopsis on these patients using three different tests: 1) Frisby; 2) Randot Preschool; and 3) Titmus fly. Results Twenty-eight patients (25%) had a positive response to at least one of the stereopsis tests. There was no statistically significant difference in stereopsis between the two treatment groups. Frisby (contact lens, 6 (11%); IOL, 7 (13%); p=0.99), Randot (contact lens, 3 (6%); IOL, 1 (2%); p=0.62) or Titmus: (contact lens, 8 (15%); IOL, 13 (23%); p=0.34). The median age at surgery for patients with stereopsis was younger than for those without stereopsis (1.2 versus 2.4 months; p=0.002). The median visual acuity for patients with stereopsis was better than for those without stereopsis (20/40 vs. 20/252; p=0.0003). Conclusion The type of optical correction did not influence stereopsis outcomes. However, two other factors did: age at surgery and visual acuity in the treated eye at age 4.5 years. Early surgery for unilateral congenital cataract and the presence of visual acuity better than or equal to 20/40 appear to be more important than the type of initial optical correction used for the development of stereopsis. PMID:25261241

  8. Two-Year Clinical Results After Selective Laser Trabeculoplasty for Normal Tension Glaucoma

    PubMed Central

    Lee, Jacky W.Y.; Shum, Jennifer J.W.; Chan, Jonathan C.H.; Lai, Jimmy S.M.

    2015-01-01

    Abstract This article aims to investigate the clinical results at 2 years after selective laser trabeculoplasty (SLT) for normal tension glaucoma (NTG). This prospective cohort study recruited NTG patients taking antiglaucoma medication. Subjects were excluded if they had previous glaucoma surgery/laser or corneal pathologies. All subjects underwent a 1-month washout. A single session of SLT was performed to 360° of the trabecular meshwork. Medication was resumed at 1 month to achieve a targeted 30% intraocular pressure (IOP) reduction from the post-washout/pre-SLT IOP. IOP was measured every 3 months and medication use was recorded at 3, 6, 12, and 24 months. Subjects with a secondary SLT or cataract extraction were excluded from IOP and medication analyses. At 24 months, 34 of the initial 45 right eyes were eligible for analyses. There were significant IOP reductions at all time intervals (except at 1 week) following SLT when compared to the prestudy (without medication) or pre-SLT (post-washout) IOP (P < 0.0001). Medications were likewise significantly reduced at all time intervals following SLT (P < 0.0001). At 24 months, the IOP was 11.5% lower than the prestudy IOP, 22.0% lower than the pre-SLT IOP, and medication use was reduced by 41.1% (P < 0.0001). Six out of 45 eyes (13.3%) required a secondary SLT. Absolute success (IOP reduction >20% from pre-SLT, without medication) was achieved in 11.1% (5/45). Reductions in IOP and medication use were evident at 2 years following SLT for the treatment of NTG whereas 11% remained medication free. Trial Registrations: The Clinical Trials Register of the University of Hong Kong HKCTR1847. The European Clinical Trials Database 2014-003305-15 (August 11, 2014).

  9. Global surgery in a postconflict setting - 5-year results of implementation in the Russian North Caucasus

    PubMed Central

    Lunze, Fatima I.; Lunze, Karsten; Tsorieva, Zemfira M.; Esenov, Constantin T.; Reutov, Alexandr; Eichhorn, Thomas; Offergeld, Christian

    2015-01-01

    Background Collaborations for global surgery face many challenges to achieve fair and safe patient care and to build sustainable capacity. The 2004 terrorist attack on a school in Beslan in North Ossetia in the Russian North Caucasus left many victims with complex otologic barotrauma. In response, we implemented a global surgery partnership between the Vladikavkaz Children's Hospital, international surgical teams, the North Ossetian Health Ministry, and civil society organizations. This study's aim was to describe the implementation and 5-year results of capacity building for complex surgery in a postconflict, mid-income setting. Design We conducted an observational study at the Children's Hospital in Vladikavkaz in the autonomous Republic of North Ossetia-Alania, part of the Russian Federation. We assessed the outcomes of 15 initial patients who received otologic surgeries for complex barotrauma resulting from the Beslan terrorism attack and for other indications, and report the incidence of intra- and postoperative complications. Results Patients were treated for trauma related to terrorism (53%) and for indications not related to violence (47%). None of the patients developed peri- or postoperative complications. Three patients (two victims of terrorism) who underwent repair of tympanic perforations presented with re-perforations. Four junior and senior surgeons were trained on-site and in Germany to perform and teach similar procedures autonomously. Conclusions In mid-income, postconflict settings, complex surgery can be safely implemented and achieve patient outcomes comparable to global standards. Capacity building can build on existing resources, such as operation room management, nursing, and anesthesia services. In postconflict environments, substantial surgical burden is not directly attributable to conflict-related injury and disease, but to health systems weakened by conflicts. Extending training and safe surgical care to include specialized

  10. Amphetamines and cannabinoids testing in hair: Evaluation of results from a two-year period.

    PubMed

    Burgueño, María José; Alonso, Amaya; Sánchez, Sergio

    2016-08-01

    This paper presents an overview of a set of amphetamines and cannabinoids tests performed on head hair samples from the Medico-Legal sector at the Madrid Department of the Spanish National Institute of Toxicology and Forensic Sciences during the years 2013 and 2014. The hair samples were tested for five stimulant phenylalkylamine derivatives -amphetamine (AP), methamphetamine (MA), 3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxy-amphetamine (MDA), and 3,4-methylenedioxy-N-ethylamphetamine (MDEA)- and/or two cannabinoids-Δ(9)-tetrahydrocannabinol (THC) and cannabinol (CBN)- by gas chromatography equipped with mass spectrometry detection in selected-ion monitoring mode, applying a method accredited to ISO/IEC 17025 standards. The test results were interpreted according to the confirmation cut-offs proposed by the Society of Hair Testing (SoHT) to identify chronic drug use. The ratios of positive results were studied in relation to gender, age, hair colour, dyeing and length of the tested samples to assess the independence from these variables or the association with them. Low, medium and high ranges of concentration were also estimated for each drug. 21.94% of the 2954 hair samples tested for phenylalkylamine derivatives were positive for one or more substances. 16.38% of the samples were positive for AP, 12.09% for MDMA and only 0.44% for MA. 6.60% of the tested samples were positive for AP/MDMA combination. A total of 3178 samples were tested for cannabinoids, resulting in 53.40% positive for THC and CBN. Simultaneous tests for phenylalkylamine derivatives and cannabinoids were performed in 2931 of the samples; 14.94% of them were positive for THC, CBN, and one or more amphetamines. According to the results from the statistical analysis, the use of THC and MDMA vary with age and gender among the Medico-Legal sector in an extended area of Spain, while the use of AP appears to be independent of these variables. On the other hand, the results of THC in

  11. Results-Based Financing in Mozambique’s Central Medical Store: A Review After 1 Year

    PubMed Central

    Spisak, Cary; Morgan, Lindsay; Eichler, Rena; Rosen, James; Serumaga, Brian; Wang, Angela

    2016-01-01

    ABSTRACT Background: Public health commodity supply chains are typically weak in low-income countries, partly because they have many disparate yet interdependent functions and components. Approaches to strengthening supply chains in such settings have often fallen short—they address technical weaknesses, but not the incentives that motivate staff to perform better. Methods: We reviewed the first year of a results-based financing (RBF) program in Mozambique, which began in January 2013. The program aimed to improve the performance of the central medical store—Central de Medicamentos e Artigos Medicos (CMAM)—by realigning incentives. We completed in-depth interviews and focus group discussions with 33 key informants, including representatives from CMAM and donor agencies, and collected quantitative data on performance measures and use of funds. Implementation: The RBF agreement linked CMAM performance payments to quarterly results on 5 performance indicators related to supply planning, distribution planning, and warehouse management. RBF is predicated on the theory that a combination of carrot and stick—i.e., shared financial incentives, plus increased accountability for results—will spur changes in behavior. Important design elements: (1) indicators were measured against quarterly targets, and payments were made only for indicators that met those targets; (2) targets were set based on documented performance, at levels that could be reasonably attained, yet pushed for improvement; (3) payment was shared with and dependent on all staff, encouraging teamwork and collaboration; (4) results were validated by verifiable data sources; and (5) CMAM had discretion over how to use the funds. Findings: We found that CMAM’s performance continually improved over baseline and that CMAM achieved many of its performance targets, for example, timely submission of quarterly supply and distribution planning reports. Warehouse indicators, such as inventory management and

  12. Bonded amalgam sealants and adhesive resin sealants: five-year clinical results.

    PubMed

    Staninec, Michal; Artiga, Nelson; Gansky, Stuart A; Marshall, Grayson W; Eakle, Stephan

    2004-05-01

    Bonded amalgams were used as pit-and-fissure sealants without mechanical preparation. They were compared with resin-based pit-and-fissure sealants for retention over a 5-year period. Clinical examinations at 6 months, 1 year, 2 years, and 5 years revealed no difference between the two techniques. Although amalgam sealants may not be practical by themselves, they can be used to seal pits and fissures surrounding very conservative preparations, in the "preventive amalgam restoration." Conventional amalgam retentive features and 90-degree cavosurface margins may not be necessary when bonding is used with amalgam. PMID:15130073

  13. A New Explanation of Globular Cluster Color Bimodality: 6-year Results and Implications

    NASA Astrophysics Data System (ADS)

    Yoon, Suk-Jin

    2012-05-01

    The colors of globular clusters (GCs) in most large early-type galaxies are bimodal. This is generally taken as evidence for the presence of two GC subpopulations with different geneses, and thus forms a critical backbone of various galaxy formation theories. However, Yoon et al. (2006, Science 311, 1129) showed that the metallicity-color relations are highly inflected due to two complementary effects: (i) the integrated color of main-sequence and giant-branch is a mild nonlinear function of metallicity, and (ii) the rapid change in color due to the onset of the hot horizontal-branch further strengthens the non-linearity. Such nonlinear nature creates ''bimodal'' color distributions of old GCs from a broad underlying metallicity spread, even if it is unimodal. In this contribution, we summarize the 6-year results of theoretical and observational studies on the ''nonlinear color-metallicity relation'' scenario for the GC color bimodality and its implications on galaxy formation theories. We show that the hypothesis gives remarkably simple and cohesive explanations for all the key observations, including the close link of the GC color distributions to the host galaxy properties and the curious discrepancy in metallicity distribution functions between GC systems and their host galaxies’ constituent stars.

  14. What makes age diverse teams effective? Results from a six-year research program.

    PubMed

    Wegge, J; Jungmann, F; Liebermann, S; Shemla, M; Ries, B C; Diestel, S; Schmidt, K-H

    2012-01-01

    Based on a new model of productivity in age diverse tams, findings from a six-year research program are reported in which data from more than 745 natural teams with 8,848 employees in three different fields (car production, administrative work, financial services) were collected. Moreover, central assumptions of this model were tested with a representative survey of the German workforce (N = 2,000). Results support both significant advantages and disadvantages for age-mixed teams. Based on the findings, the following preconditions for the effectiveness of age diverse teams are identified: high task complexity, low salience and high appreciation of age diversity, a positive team climate, low age-discrimination, ergonomic design of work places, and the use of age differentiated leadership. Based on these insights, we developed a new training for supervisors, which addresses the aforementioned aspects and seeks to improve team performance and health of team members. It was found that the training reduces age stereotypes, team conflicts and enhances innovation. Thus, we can conclude that effective interventions for a successful integration of elderly employees in work groups are available and that combinations of measures that address ergonomic design issues, team composition and leadership are to be strongly recommended for practice. PMID:22317517

  15. Two-year results of intravitreal ranibizumab for polypoidal choroidal vasculopathy with recurrent or residual exudation

    PubMed Central

    Saito, M; Iida, T; Kano, M; Itagaki, K

    2013-01-01

    Aim To clarify the 2-year efficacy of ranibizumab for patients with polypoidal choroidal vasculopathy (PCV) with recurrent or residual exudation from branching vascular networks after previous photodynamic therapy (PDT). Methods We retrospectively reviewed 26 eyes of 26 Japanese patients (22 men, 4 women) in this pilot study. All eyes had PCV with complete regression of polypoidal lesions resulting from PDT detected by indocyanine green angiography (ICGA), but recurrent or residual leakage from branching vascular networks on fluorescein angiography and evidence of persistent fluid on optical coherence tomography (OCT). Three consecutive intravitreal injections of ranibizumab (0.5 mg/0.05 ml) were administered to all eyes. Results The mean logarithm of the minimum angle of resolution best-corrected visual acuity (BCVA) improved significantly from 0.55 at baseline to 0.35 at 12 months (P<0.0001) and 0.43 at 24 months (P=0.0012). The mean increases in the BCVA 12 and 24 months after baseline were 1.95 and 1.23 lines, respectively. The mean central retinal thickness significantly decreased from 295 μm at baseline to 189 μm at 12 months (P<0.0038) and 163 μm at 24 months (P<0.001). The mean numbers of intravitreal ranibizumab (IVR) injections at months 12 and 24, including the initial treatments, were 5.8 and 8.8, respectively. Five (19.2%) eyes had recurrent polypoidal lesions on ICGA at a mean of 15.7 months after baseline. At month 24, OCT showed no exudation in 17 (65.4%) of the 26 eyes. No adverse events developed. Conclusions IVR injections maintained or improved the VA and retinal thickness at 24 months in eyes with PCV with recurrent or residual exudation from branching vascular networks after previous PDT. PMID:23743532

  16. New vertebral fractures after vertebroplasty: 2 year results from a randomised controlled trial

    PubMed Central

    Staples, MP; Howe, BM; Ringler, MD; Mitchell, P; Wriedt, CHR; Wark, JD; Ebeling, PR; Osborne, RH; Kallmes, DF; Buchbinder, R

    2015-01-01

    Purpose To assess the effect of vertebroplasty (VP) on the risk of further radiologically apparent vertebral fracture within two years of the procedure. Methods We conducted a randomised placebo-controlled trial of VP in people with acute osteoporotic vertebral fracture. Eligible participants were randomly assigned to VP (n=38) or placebo (n=40). Cement volume and leakage were recorded for the VP group. Plain thoracolumbar radiographs were taken at baseline, 12 and 24 months. Two independent radiologists assessed these for new and progressed fractures at the same, adjacent and non-adjacent levels. Results At 12 and 24 months, radiographs were available for 45 (58%) and 47 (60%) participants respectively. There were no between-group differences for new or progressed fractures: 32 and 40 in the VP group after 12 and 24 months compared with 21 and 33 in the placebo group (hazard ratio (HR) 1.80, 95% confidence interval (CI) 0.82 to 3.94). Similar results were seen when considering only adjacent (HR (95% CI): 2.30 (0.57 to 9.29)), and non-adjacent (HR (95% CI): 1.45 (0.55 to 3.81) levels. In all comparisons there was a consistent trend towards higher risk of any type of fracture in the group undergoing VP. Within the VP group, fracture risk was unrelated to total (HR (95% CI): 0.91 (0.71 to 1.17)) or relative (HR (95% CI): 1.31 (0.15 to 11.48)) cement volume, or cement leakage (HR (95% CI): 1.20 (0.63 to 2.31)). Conclusion For patients undergoing VP our study did not demonstrate significant increases in subsequent fracture risk beyond that experienced by those with vertebral fractures who did not undergo the procedure. However, because of the non-significant numerical increases observed, studies with adequate power are needed to draw definite conclusions about fracture risk. PMID:26272712

  17. Multicenter Collaborative Quality Assurance Program for the Province of Ontario, Canada: First-Year Results

    SciTech Connect

    Létourneau, Daniel; McNiven, Andrea; Jaffray, David A.

    2013-05-01

    Purpose: The objective of this work was to develop a collaborative quality assurance (CQA) program to assess the performance of intensity modulated radiation therapy (IMRT) planning and delivery across the province of Ontario, Canada. Methods and Materials: The CQA program was designed to be a comprehensive end-to-end test that can be completed on multiple planning and delivery platforms. The first year of the program included a head-and-neck (H and N) planning exercise and on-site visit to acquire dosimetric measurements to assess planning and delivery performance. A single dosimeter was used at each institution, and the planned to measured dose agreement was evaluated for both the H and N plan and a standard plan (linear-accelerator specific) that was created to enable a direct comparison between centers with similar infrastructure. Results: CQA program feasibility was demonstrated through participation of all 13 radiation therapy centers in the province. Planning and delivery was completed on a variety of infrastructure (treatment planning systems and linear accelerators). The planning exercise was completed using both static gantry and rotational IMRT, and planned-to-delivered dose agreement (pass rates) for 3%/3-mm gamma evaluation were greater than 90% (92.6%-99.6%). Conclusions: All centers had acceptable results, but variation in planned to delivered dose agreement for the same planning and delivery platform was noted. The upper end of the range will provide an achievable target for other centers through continued quality improvement, aided by feedback provided by the program through the use of standard plans and simple test fields.

  18. Lithospheric Structure of East Antarctica: Results From the First Year of the SSCUA Broadband Seismic Deployment

    NASA Astrophysics Data System (ADS)

    Reading, A. M.

    2004-12-01

    Recent geological and geochronological work has changed our concept of the former Gondwana continents surrounding a central Archaean craton, East Antarctica. The revised tectonic framework shows mobile belts and tectonic province boundaries which correlate well with East Antarctica's former neighbours in the supercontinent and trend perpendicular to the present day Antarctic coastline. Constraints are however restricted to those areas where the rock is exposed above the ice. Indirect, geophysical methods are required to map the extent of tectonic provinces in the continental interior and provide information on the deep structure. Following a pilot deployment in 2001/02, a set of 6 remote broadband earthquake recording stations were deployed in the Lambert Glacier region, East Antarctica, from the coast at 65°S deep into the interior to a latitude of 75°S. The aim was to determine the Seismic Structure of the Continent Under Antarctica (SSCUA) using a variety of seismological techniques. The stations were solar-powered and hence shut down during the Antarctic winter to re-commence recording after the return of daylight in the austral spring. After one year, 3 stations were relocated to further test contemporary terrane models of the lithosphere in this region. At the present time (December 2004) recording continues across the deployment with most stations due to be uplifted at the end of the 2004/05 summer season. Results of receiver function inversions for seismic structure beneath the recording stations of the first main deployment are presented. To the west of the Lambert Glacier, the Rayner province extends from Mawson Station to Beaver Lake with a fairly deep Moho at 42 km. To the east, seismic velocity profiles have a different character, showing slower crustal velocities. A province boundary exists between the Reinbolt Hills and the northern Mawson Escarpment where the crust is shallower at 34 km. These results are the first determinations of the seismic

  19. Ionosphere over Africa: Results from Geomagnetic Field Measurements During International Heliophysical Year IHY

    NASA Astrophysics Data System (ADS)

    Rabiu, A. B.; Yumoto, K.; Falayi, E. O.; Bello, O. R.; Magdas/Cpmn Group

    2011-12-01

    Space Environment Research Centre of Kyushu University, Japan, installed 13 units of Magnetic Data Acquisition Systems MAGDAS over Africa during the International Heliophysical Year IHY. Magnetic records from 10 stations along the African 96o Magnetic Meridian (Geographical 30° - 40° East) were examined for Solar quiet daily Sq variations in the two geomagnetic field components H and D. Latitudinal variations of Sq in the geomagnetic components were examined. Signatures of equatorial electrojet and worldwide Sq were identified and studied in detail. H field experienced more variation within the equatorial electrojet zone. Diurnal variations of the geomagnetic variations in the two components were discussed. Sq H is expectedly consistently maximum within the electrojet zone as a result of EEJ. Sq D has maximum values at about -20ɛ (sunrise), -10ɛ (noon time) and +10ɛ (sunset). Levels of inter-relationships between the Sq and its variability in the two components were statistically derived and interpreted in line with the mechanisms responsible for the variations of the geomagnetic field. Data from 2 magnetic observatories within equatorial electrojet EEJ strip and 2 stations outside the EEJ strip were employed to evaluate and study the signatures of the Equatorial electrojet over the African sector. The transient variations of the EEJ at two almost parallel axes using Lagos-Ilorin (West Africa) and Nairobi-Addis Ababa (East Africa) pairs were examined. The eastern electrojet appeared stronger than the western. The latitudinal and longitudinal profiles of the Sq were examined and inferences drawn from observed results were discussed.

  20. [Results of radiotherapy in the year of the Röntgen centenary].

    PubMed

    Esik, O

    1998-03-01

    In 1996, the three leading radiation oncology periodicals (Int. J. Radiat. Oncol. Biol. Phys.--USA, Radiother. Oncol.--Europe, and Strahlenther. Onkol.--Germany) published 681 papers. Among the different topics, the clinical subjects accounted for almost half (46%) of the total number of publications, followed by radiation physics/techniques (18%) and radiation biology (17%). The 13% of editorials/review articles reflects a considerable endeavor towards integration; the contribution of papers relating to professional organization amounted to 2%. The fact that 1996 was the centennial year of the discovery of the Röntgen rays explains the reasonable proportion (4%) of historical reviews. Within the special topics, prostatic cancer and breast cancer were the two most frequent issues. Dose escalation was the most important tool applied to improve the results of the radiation therapy of tumors with unfavorable prognostic signs or radioresistance. The increase in the applied dose was made possible by a decrease in the planning target volume (PTV), 3D forward and inverse radiation treatment planning, a combination of tomographic (CT/MRI/US) diagnostic methods (image registration/fusion), optimizing algorithms, computer-controlled delivery of radiation dose and electronic portal imaging with in vivo dosimetry. In contrast, the trends in the radiotherapy of tumors with favorable long-term survival (e.g. Hodgkin's disease and seminoma) include a decreased dose and PTV reduction to diminish the late, radiation-related morbidity. Fractionation has remained the only tool of radiobiology routinely used in the everyday clinical practice. A comparison of the results and achievements in the special fields reveals that radiation physics/techniques clearly outstrip clinical subjects and especially radiation biology, as they allow direct and instant exploitation of the advantages offered by computers. It is highly probable, however, that, subsequent to a wider use of computers in

  1. Five-Year Wilkinson Microwave Anisotropy Probe Observations: Data Processing, Sky Maps, and Basic Results

    NASA Technical Reports Server (NTRS)

    Hinshaw, G.; Weiland, J. L.; Hill, R. S.; Odegard, N.; Larson, D.; Bennett, C. L.; Dunkley, J.; Gold, B.; Greason, M. R.; Jarosik, N.; Komatsu, E.; Nolta, M. R.; Page, L.; Spergel, D. N.; Wollack, E.; Halpern, M.; Kogut, A.; Limon, M.; Meyer, S. S.; Tucker, G. S.; Wright, E. L.

    2010-01-01

    We present new full-sky temperature and polarization maps in five frequency bands from 23 to 94 GHz, based on data from the first five years of the Wilkinson Microwave Anisotropy Probe (WMAP) sky survey. The new maps are consistent with previous maps and are more sensitive. The five-year maps incorporate several improvements in data processing made possible by the additional years of data and by a more complete analysis of the instrument calibration and in-flight beam response. We present several new tests for systematic errors in the polarization data and conclude that W-band polarization data is not yet suitable for cosmological studies, but we suggest directions for further study. We do find that Ka-band data is suitable for use; in conjunction with the additional years of data, the addition of Ka band to the previously used Q- and V-band channels significantly reduces the uncertainty in the optical depth parameter, tau. Further scientific results from the five-year data analysis are presented in six companion papers and are summarized in Section 7 of this paper. With the five-year WMAP data, we detect no convincing deviations from the minimal six-parameter ACDM model: a flat universe dominated by a cosmological constant, with adiabatic and nearly scale-invariant Gaussian fluctuations. Using WMAP data combined with measurements of Type Ia supernovae and Baryon Acoustic Oscillations in the galaxy distribution, we find (68% CL uncertainties): OMEGA(sub b)h(sup 2) = 0.02267(sup +0.00058)(sub -0.00059), OMEGA(sub c)h(sup 2) = 0.1131 plus or minus 0.0034, OMEGA(sub logical and) = 0.726 plus or minus 0.015, ns = .960 plus or minus 0.013, tau = 0.84 plus or minus 0.016, and DELTA(sup 2)(sub R) = (22.445 plus or minus 0.096) x 10(exp -9) at k = 0.002 Mpc(exp -1). From these we derive sigma(sub 8) = 0.812 plus or minus 0.026, H(sub 0) = 70.5 plus or minus 1.3 kilometers per second Mpc(exp -1), OMEGA(sub b) = 0.0456 plus or minus 0.0015, OMEGA(sub c) = .228 plus or minus

  2. Third-Year Results from the Circumarctic Lakes Observation Network (CALON) Project

    NASA Astrophysics Data System (ADS)

    Hinkel, K. M.; Arp, C. D.; Beck, R. A.; Eisner, W. R.; Frey, K. E.; Grosse, G.; Jones, B. M.; Kim, C.; Lenters, J. D.; Liu, H.; Townsend-Small, A.

    2014-12-01

    Since 2012, 60 lakes in northern Alaska have been instrumented under the auspices of CALON, a project designed to document landscape-scale variability in physical and biogeochemical processes of Arctic lakes in permafrost terrain. The network has ten observation nodes along two latitudinal transects extending from the Arctic Ocean inland some 200 km to the Brooks Range foothills. At each node, a meteorological station is deployed, and six representative lakes of differing area and depth are instrumented and sampled at different intensity levels to collect basic field measurements. In April, sensors measuring water temperature and depth are deployed through the ice in each lake, ice and snow thickness recorded, and water samples are collected. Data are downloaded, lakes re-sampled, and bathymetric surveys are conducted in August. In 2014, the snow cover on inland lakes was thinner than in previous years but thicker on lakes located near the coast. Lake ice was generally thinner near the coast, but the difference diminished inland. Winters (Oct-March) have been progressively warmer over the 3-year period, which partially explains the thinner lake ice that formed in 2013-14. Lakes are typically well-mixed and largely isothermal, with minor thermal stratification occurring in deeper lakes during calm, sunny periods. These regional lake and meteorological data sets, used in conjunction with satellite imagery, supports the wind-driven lake circulation model for the origin of thermokarst lakes. Results of biogeochemical analyses of lake waters generally show notably higher concentrations of cations/anions, chromophoric dissolved organic matter, and chlorophyll-a during April as compared with August. Dissolved methane concentrations are also much higher under ice than in open water during summer, although all lakes are a source of atmospheric methane. Interviews with indigenous elders in Anaktuvuk Pass indicate that mountain lakes are drying up. During the 2014 breakup

  3. Results of a Two-Year Longitudinal Study of Beverage-Specific Alcohol Use among Adolescents

    ERIC Educational Resources Information Center

    Moore, Michele Johnson; Werch, Chudley

    2007-01-01

    This study explored beverage-specific alcohol consumption patterns among a sample of high school students over a two-year period. Four hundred fifty-five students completed the validated questionnaire at all three time points (2002, 2003, 2004). Variables of interest included five use measures (past year use, 30-day frequency, quantity, heavy use,…

  4. Utilizing First-Year Curricula Linkage to Improve In-Major Persistence to Graduation: Results from a Four-Year Longitudinal Study, Fall 2000-Spring 2004

    ERIC Educational Resources Information Center

    Lifton, Donald; Cohen, Alan; Schlesinger, Warren

    2008-01-01

    Academic departments have expanded the typical persistence agenda of First-Year Seminars to use them specifically as tools for in-major retention. This article reports the empirical results of a four-year longitudinal study assessing the successful efforts to improve the persistence-to-graduation-within-major of business students. The pedagogy can…

  5. ESA SMART-1 mission: review of results and legacy 10 years after launch

    NASA Astrophysics Data System (ADS)

    Foing, Bernard

    2014-05-01

    We review ESA's SMART-1 highlights and legacy 10 years after launch. The SMART-1 mission to the Moon achieved record firsts such as: 1) first Small Mission for Advanced Research and Technology; with spacecraft built and integrated in 2.5 years and launched 3.5 years after mission approval; 2) first mission leaving the Earth orbit using solar power alone with demonstration for future deep space missions such as BepiColombo; 3) most fuel effective mission (60 litres of Xenon) and longest travel (13 month) to the Moon!; 4) first ESA mission reaching the Moon and first European views of lunar poles; 5) first European demonstration of a wide range of new technologies: Li-Ion modular battery, deep-space communications in X- and Ka-bands, and autonomous positioning for navigation; 6) first lunar demonstration of an infrared spectrometer and of a Swept Charge Detector Lunar X-ray fluorescence spectrometer ; 7) first ESA mission with opportunity for lunar science, elemental geochemistry, surface mineralogy mapping, surface geology and precursor studies for exploration; 8) first controlled impact landing on the Moon with real time observations campaign; 9) first mission supporting goals of the ILEWG/COSPAR International Lunar Exploration Working Group in technical and scientific exchange, international collaboration, public and youth engagement; 10) first mission preparing the ground for ESA collaboration in Chandrayaan-1, Chang'E1-2-3 and near-future landers, sample return and human lunar missions. The SMART-1 technology legacy is applicable to geostationary satellites and deep space missions using solar electric propulsion. The SMART-1 archive observations have been used to support scientific research and prepare subsequent lunar missions and exploration. Most recent SMART-1 results are relevant to topics on: 1) the study of properties of the lunar dust, 2) impact craters and ejecta, 3) the study of illumination, 4) observations and science from the Moon, 5) support to

  6. [Results of 3-year study of toothbrushing with a fluoride amine gel].

    PubMed

    Szöke, J; Kozma, M

    1989-12-01

    265 6-year-old children were investigated over a period of 3 years. In the test group, 6 toothbrushing exercises and 25-30 controlled applications of Elmex Gelèe were carried out yearly. The effect was analyzed by oral hygiene, caries frequency, caries intensity, and caries increase. The improvement of the oral hygiene index according to Silness-Löe was 30% and can be characterized as highly statistically significant (p less than 0.001). The inhibition of caries increase related to the surface (delta DMF-S) was 53% in the case of caries with substance loss and was also highly significant. PMID:2639721

  7. Vehicle technologies program Government Performance and Results Act (GPA) report for fiscal year 2012

    SciTech Connect

    Ward, J.; Stephens, T. S.; Birky, A. K.

    2012-08-10

    The U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy has defined milestones for its Vehicle Technologies Program (VTP). This report provides estimates of the benefits that would accrue from achieving these milestones relative to a base case that represents a future in which there is no VTP-supported vehicle technology development. Improvements in the fuel economy and reductions in the cost of light- and heavy-duty vehicles were estimated by using Argonne National Laboratory's Autonomie powertrain simulation software and doing some additional analysis. Argonne also estimated the fraction of the fuel economy improvements that were attributable to VTP-supported development in four 'subsystem' technology areas: batteries and electric drives, advanced combustion engines, fuels and lubricants, and materials (i.e., reducing vehicle mass, called 'lightweighting'). Oak Ridge National Laboratory's MA{sup 3}T (Market Acceptance of Advanced Automotive Technologies) tool was used to project the market penetration of light-duty vehicles, and TA Engineering's TRUCK tool was used to project the penetrations of medium- and heavy-duty trucks. Argonne's VISION transportation energy accounting model was used to estimate total fuel savings, reductions in primary energy consumption, and reductions in greenhouse gas emissions that would result from achieving VTP milestones. These projections indicate that by 2030, the on-road fuel economy of both light- and heavy-duty vehicles would improve by more than 20%, and that this positive impact would be accompanied by a reduction in oil consumption of nearly 2 million barrels per day and a reduction in greenhouse gas emissions of more than 300 million metric tons of CO{sub 2} equivalent per year. These benefits would have a significant economic value in the U.S. transportation sector and reduce its dependency on oil and its vulnerability to oil price shocks.

  8. Cross-year peer tutoring on internal medicine wards: results of a qualitative focus group analysis

    PubMed Central

    Krautter, Markus; Andreesen, Sven; Köhl-Hackert, Nadja; Hoffmann, Katja; Herzog, Wolfgang; Nikendei, Christoph

    2014-01-01

    Background Peer-assisted learning (PAL) has become a well-accepted teaching method within medical education. However, descriptions of on-ward PAL programs are rare. A focus group analysis of a newly established PAL program on an internal medicine ward was conducted to provide insights into PAL teaching from a student perspective. Purpose To provide insights into students’ experiences regarding their on-ward training with and without accompanying PAL tutors. Methods A total of N=168 medical students in their sixth semester participated in the investigation (intervention group: N=88; control group: N=80). The intervention group took part in the PAL program, while the control group received standard on-ward training. There were seven focus groups with N=43 participants (intervention group: four focus groups, N=28 participants; control group: three focus groups, N=15 participants). The discussions were analyzed using content analysis. Results The intervention group emphasized the role of the tutors as competent and well-trained teachers, most beneficial in supervising clinical skills. Tutors motivate students, help them to integrate into the ward team, and provide a non-fear-based working relationship whereby students’ anxiety regarding working on ward decreases. The control group had to rely on autodidactic learning strategies when neither supervising physicians nor final-year students were available. Conclusion On-ward PAL programs represent a particularly valuable tool for students’ support in training clinical competencies on ward. The tutor–student working alliance acts through its flat hierarchy. Nevertheless, tutors cannot represent an adequate substitute for experienced physicians. PMID:25278789

  9. Biofilters to treat the pesticides wastes from spraying applications: results after 4 years of study.

    PubMed

    Pigeon, O; De Vleeschouwer, C; Cors, F; Weickmans, B; Huyghebaert, B; Planchon, V; Pussemier, L; Culot, M

    2006-01-01

    Biofilters were developed in order to eliminate or reduce the quantity of pesticides from rinsing and cleaning waters of sprayers. Biofilters consist in 1, 2 or 3 plastic containers of 1 m3 placed in a vertical pile and containing a substrate elaborated from a homogenised mixture of local soil, chopped straw and compost able to absorb and degrade the pesticides. Biofilters are installed near the area for cleaning and rinsing the sprayer and the waste waters are pumped into the system. Since 2002, a pilot study is carried out in Belgium in order to evaluate the efficacy of these systems. Twenty pilot systems were installed since 2002 until 2004 in several farms, agricultural technical centres or schools and in a municipal maintenance service. The efficacy of the biofilters was studied for several chemical classes of herbicides (sulfonylurea, aryloxyalcanoic acids, chloroacetanilides), insecticides (pyrethroids, carbamates) and fungicides (dicarboximides, phenylamides, triazoles and strobilurines). The balance of the inputs and the outputs of the pesticides was determined by monitoring the elutes. The degradation kinetic of pesticides into the substrate was evaluated by analysing the pesticides into the substrate. The microbiological activity of the substrate was also evaluated by measuring respiration and some indirect parameters like dry matter content, Kjeldahl nitrogen content, organic carbon content and biological oxygen demand (BOD). Results obtained until now after four years of experiments have showed an overall good efficacy (retention) of pesticides by the biofilter and a high degradation rate for the majority of pesticides. Biofilters permit to reduce highly the quantity of pesticides from rinsing and cleaning waters of sprayers and contribute significantly to the reduction of the contamination of surface water. Biofilters are now registered by the Ministry of Agriculture and Environment of the Walloon Region in Belgium and are recommended to pesticides

  10. One-year results of an algorithmic approach to managing failed back surgery syndrome

    PubMed Central

    Avellanal, Martín; Diaz-Reganon, Gonzalo; Orts, Alejandro; Soto, Silvia

    2014-01-01

    BACKGROUND: Failed back surgery syndrome (FBSS) is a major clinical problem. Different etiologies with different incidence rates have been proposed. There are currently no standards regarding the management of these patients. Epiduroscopy is an endoscopic technique that may play a role in the management of FBSS. OBJECTIVE: To evaluate an algorithm for management of severe FBSS including epiduroscopy as a diagnostic and therapeutic tool. METHODS: A total of 133 patients with severe symptoms of FBSS (visual analogue scale score ≥7) and no response to pharmacological treatment and physical therapy were included. A six-step management algorithm was applied. Data, including patient demographics, pain and surgical procedure, were analyzed. In all cases, one or more objective causes of pain were established. Treatment success was defined as ≥50% long-term pain relief maintained during the first year of follow-up. Final allocation of patients was registered: good outcome with conservative treatment, surgical reintervention and palliative treatment with implantable devices. RESULTS: Of 122 patients enrolled, 59.84% underwent instrumented surgery and 40.16% a noninstrumented procedure. Most (64.75%) experienced significant pain relief with conventional pain clinic treatments; 15.57% required surgical treatment. Palliative spinal cord stimulation and spinal analgesia were applied in 9.84% and 2.46% of the cases, respectively. The most common diagnosis was epidural fibrosis, followed by disc herniation, global or lateral stenosis, and foraminal stenosis. CONCLUSIONS: A new six-step ladder approach to severe FBSS management that includes epiduroscopy was analyzed. Etiologies are accurately described and a useful role of epiduroscopy was confirmed. PMID:25222573

  11. Results of many-year subsatellite measurements of current fine structure in northeastern Black Sea

    NASA Astrophysics Data System (ADS)

    Lavrova, Olga; Krayushkin, Evgeny; Kalashnikova, Nina

    Results of subsatellite measurements of coastal currents in the shelf zone of northeastern Black Sea are presented. The measurements have been performed every year since 2006 in June and September-October months near the Gelendzhik Bay. The main instruments used are Acoustic Doppler Current Profilers (ADCP) and CTD probes. Ground and ship measurements were conducted simultaneously with satellite imaging in microwave (ASAR Envisat, ERS-2, RADARSAT-2, TerraSAR-X), visible and infrared (OLI Landsat-8, ETM+ Landsat-7, TM Landsat-5, MODIS Terra/Aqua, AVHRR NOAA) ranges. The investigations performed revealed spatial, depth and temporal variability of current direction and velocity in the shelf zone. Multiple instances of counter-currents opposing to the Ring Current were registered. In our view, they are associated with a passage of small-scale anticyclonic eddies across the region of interest. The 3D structure of the eddies in the upper quasi-uniform layer was analyzed based on ADCP data. The use of high resolution (3 m) SAR data in combination with ADCP measurements at the resolution of 0.5 m allowed us to detect a number of internal wave trains. Form ADCP and thermistors records, their amplitudes were estimated to reach 5-8 m. Joint analysis of satellite SAR and subsatellite data gave an assessment of their typical wavelength at 90-100 m. Generation mechanisms of these internal waves are suggested. Another phenomenon of interest observed in the region of the measurements is surface manifestations of ring waves near localized natural and anthropogenic generation sources. Such ring waves are most frequently found in the anchor area for ships, whose oscillations can be the source of their generation. The work was in part supported by the Russian Foundation for Basic Research (projects #14-05-00520-а, and 13-07-12017-ofi_m). SAR data from RADARSAT-2 and TerraSAR-X were obtained under SOAR RADARSAT-2/TerraSAR-X Project #5074.

  12. Preparing students in two-year colleges for geoscience degrees and careers: Workshop results

    NASA Astrophysics Data System (ADS)

    Macdonald, H.; Baer, E. M.; Blodgett, R. H.; Hodder, J.

    2012-12-01

    Building a strong and diverse geoscience workforce is a critical national challenge. Two-year colleges (2YCs) play an important role in increasing both the number and diversity of geoscience graduates. A workshop on Preparing Students from Two-year Colleges for Geoscience Degrees and Careers was held in Tacoma, WA in July 2012 to discuss the successes and challenges of programs, strategies, and activities that support career preparation of 2YC students for geoscience careers, either as geotechnical graduates or as geoscience majors at four-year colleges and universities, and to make recommendations for future efforts. At the workshop several successful partnerships between employers and two-year colleges as well as between two-year colleges and four-year institutions were discussed as potential models that could be replicated with adaptations for local employment needs. Participants shared successful techniques for supporting 2YC students in their career path such as internships, early opportunities for participating in research, joint fieldtrips with transfer institutions, and supportive curriculum alignment between two and four-year institutions. Professional organizations have much to offer including information about career options, networking opportunities, and more. Participants discussed strategies for supporting geoscience workforce development at 2YCs such as making connections between 2YCs and local employers, identifying geoscience students at 2YCs who are planning to transfer and building relationships with 4YCs, establishing internship programs, supporting student geoscience clubs, and developing a repository of geoscience employment information targeted to 2YC students. Participants recognized significant barriers to incorporating career training and information into the geoscience curriculum at two-year colleges. These barriers include a predominance of non-geoscience students in classes, lack of support or rewards for improving or increasing the

  13. Second-Year Results from the Circumarctic Lakes Observation Network (CALON) Project

    NASA Astrophysics Data System (ADS)

    Hinkel, K. M.; Arp, C. D.; Beck, R. A.; Eisner, W. R.; Frey, K. E.; Gaglioti, B.; Grosse, G.; Jones, B. M.; Kim, C.; Lenters, J. D.; Liu, H.; Townsend-Small, A.

    2013-12-01

    temperatures in small shallow lakes and more southern latitudes. Most lakes are well-mixed and largely isothermal, with short periods of thermal stratification occurring in deeper lakes during calm, sunny periods. Over the ice-free season, the majority of the available energy from net radiation goes into evaporation, followed by sensible heat flux and warming of bottom sediments. Thermal bands of MODIS and Landsat imagery were fused using a spatio-temporal cokriging method to generate daily surface temperature estimates at Landsat spatial resolution. The close correspondence between satellite-derived and in situ measured near-surface lake temperature suggests that this approach yields viable results. Biogeochemical and inorganic geochemical constituents measured include dissolved greenhouse gas concentrations (CO2, CH4, and N2O), inorganic N, DON and DOC, alkalinity, chlorophyll-a, major ions, and CDOM. The greatest difference in the dissolved CH4:CO2 ratio in summer was longitudinal, with several lakes in western Alaskan Arctic exhibiting CH4 concentrations hundreds of times more supersaturated than air. Stable isotope analyses of CH4 (δ13C and δ2H) show that several of these lakes have natural gas methane sources. Methane concentrations under ice (April) were several thousand times higher than in open-water conditions (August). Data collected during this 4-year project are archived at A-CADIS.

  14. 50 years of monitoring of the ozone layer in the Czech Republic - results and challenges

    NASA Astrophysics Data System (ADS)

    Vanicek, Karel; Skrivankova, Pavla; Metelka, Ladislav; Stanek, Martin

    2010-05-01

    preferred to continue the TOZ data series at SOO the seasonal effect need to be eliminated to avoid their effect in trend estimations and validation of satellite observations.. This is going to be done by assimilation of the Dobson data series to the Brewer one and creation of the homogenized data set. - The Brewer Umkehr observations have been implemented at the SOO in the recent years to expand measurements of vertical distribution of ozone in stratosphere over Central Europe. Accuracy of the new UM-04 algorithm developed for processing of the Umkehr profiles from SOO is being tested using the ozone sonde observations from AD. First results confirm a good perspective of this technology for implementation in the global network. Further improvement of monitoring and investigation of stratospheric ozone continues in the CHMI. Currently the activities are supported by the project P209/10/0058 "Long-term changes of the ozone layer over the Czech territory" of the Czech Grant Agency (2010-2012). The main goals of the Project are defined are specified in the presentation.

  15. Translating theory into practice: results of a 2-year trial for the LEAD programme.

    PubMed

    Shelton, D

    2008-05-01

    This paper presents data for 2 years of a continuing study aimed to reduce the risk of first-time involvement by minority youth with the juvenile justice system. A quasi-experimental design was used to test a 14-week expressive art curriculum (LEAD: leadership, education, achievement and development) implemented in two rural communities. A total of 70 African American youth participated in the programme over a 2-year period. Pre- and post-test differences were examined for protective factors, behavioural self-control, self-esteem and resilience measures. When compared with the after-school programme (control group), youth in the LEAD programme in both communities had more dramatic increases in post-test scores following the intervention. The combined data from year 1 and year 2 provide positive findings in support of LEAD as a prevention programme for young offenders. The placement of the programme within an African American church in year 2 improved the processes of the LEAD programme and seemed to provide a better fit with the original design of the programme, highlighting the importance of the context, in which the programme was provided. PMID:18387150

  16. Comparing gender awareness in Dutch and Swedish first-year medical students - results from a questionaire

    PubMed Central

    2012-01-01

    Background To ascertain good and appropriate healthcare for both women and men implementation of gender perspectives in medical education is needed. For a successful implementation, knowledge about students' attitudes and beliefs about men, women, and gender is crucial. The aim of this study was to compare attitudes to gender and gender stereotyping among Dutch and Swedish male and female medical students. Methods In this cross-sectional study, we measured the attitudes and assumptions about gender among 1096 first year medical students (616 Dutch and 480 Swedish) with the validated Nijmegen Gender Awareness in Medicine Scale (N-GAMS). The response rate was 94% in the Netherlands and 93% in Sweden. Univariate analysis of variance (ANOVA) was used to compare the scores between Dutch and Swedish male and female students. Linear regressions were used to analyze the importance of the background variables. Results There were significant differences in attitudes to gender between Dutch and Swedish students. The Swedish students expressed less stereotypical thinking about patients and doctors and the Dutch were more sensitive to gender differences. The students' sex mattered for gender stereotyping, with male students in both countries agreeing more with stereotypical statements. Students' age, father's birth country and mother's education level had some impact on the outcome. Conclusions There are differences between cultures as well as between men and women in gender awareness that need to be considered when implementing gender in medical education. This study suggests that to arouse the students' interest in gender issues and make them aware of the significance of gender in medical work, the examples used in discussions need to be relevant and challenging in the context of the specific country. Due to different levels of knowledge and different attitudes within the student population it is important to create a climate for dialogue where students feel permitted to

  17. AMIE SMART-1: review of results and legacy 10 years after launch

    NASA Astrophysics Data System (ADS)

    Josset, Jean-Luc; Souchon, Audrey; Josset, Marie; Foing, Bernard

    2014-05-01

    The Advanced Moon micro-Imager Experiment (AMIE) camera was launched in September 2003 onboard the ESA SMART-1 spacecraft. We review the technical characteristics, scientific objectives and results of the instrument, 10 years after its launch. The AMIE camera is an ultra-compact imaging system that includes a tele-objective with a 5.3° x 5.3° field of view and an imaging sensor of 1024 x 1024 pixels. It is dedicated to spectral imaging with three spectral filters (750, 915 and 960 nm filters), photometric measurements (filter free CCD area), and Laser-link experiment (laser filter at 847 nm). The AMIE camera was designed to acquire high-resolution images of the lunar surface, in white light and for specific spectral bands, under a number of different viewing conditions and geometries. Specifically, its main scientific objectives included: (i) imaging of high latitude regions in the southern hemisphere, in particular the South Pole Aitken basin and the permanently shadowed regions close to the South Pole; (ii) determination of the photometric properties of the lunar surface from observations at different phase angles (physical properties of the regolith); (iii) multi-band imaging for constraining the chemical and mineral composition of the surface; (iv) detection and characterisation of lunar non-mare volcanic units; (v) study of lithological variations from impact craters and implications for crustal heterogeneity. The study of AMIE images enhanced the knowledge of the lunar surface, in particular regarding photometric modelling and surface physical properties of localized lunar areas and geological units. References: http://scholar.google.nl/scholar?q=smart-1+amie We acknowledge ESA, member states, industry and institutes for their contribution, and the members of the AMIE Team: J.-L. Josset, P. Plancke, Y. Langevin, P. Cerroni, M. C. De Sanctis, P. Pinet, S. Chevrel, S. Beauvivre, B.A. Hofmann, M. Josset, D. Koschny, M. Almeida, K. Muinonen, J. Piironen, M. A

  18. Respiratory disease mortality among US coal miners; results after 37 years of follow-up

    PubMed Central

    Graber, Judith M; Stayner, Leslie T; Cohen, Robert A; Conroy, Lorraine M; Attfield, Michael D

    2015-01-01

    Objectives To evaluate respiratory related mortality among underground coal miners after 37 years of follow-up. Methods Underlying cause of death for 9033 underground coal miners from 31 US mines enrolled between 1969 and 1971 was evaluated with life table analysis. Cox proportional hazards models were fitted to evaluate the exposure-response relationships between cumulative exposure to coal mine dust and respirable silica and mortality from pneumoconiosis, chronic obstructive pulmonary disease (COPD) and lung cancer. Results Excess mortality was observed for pneumoconiosis (SMR=79.70, 95% CI 72.1 to 87.67), COPD (SMR=1.11, 95% CI 0.99 to 1.24) and lung cancer (SMR=1.08; 95% CI 1.00 to 1.18). Coal mine dust exposure increased risk for mortality from pneumoconiosis and COPD. Mortality from COPD was significantly elevated among ever smokers and former smokers (HR=1.84, 95% CI 1.05 to 3.22; HRK=1.52, 95% CI 0.98 to 2.34, respectively) but not current smokers (HR=0.99, 95% CI 0.76 to 1.28). Respirable silica was positively associated with mortality from pneumoconiosis (HR=1.33, 95% CI 0.94 to 1.33) and COPD (HR=1.04, 95% CI 0.96 to 1.52) in models controlling for coal mine dust. We saw a significant relationship between coal mine dust exposure and lung cancer mortality (HR=1.70; 95% CI 1.02 to 2.83) but not with respirable silica (HR=1.05; 95% CI 0.90 to 1.23). In the most recent follow-up period (2000–2007) both exposures were positively associated with lung cancer mortality, coal mine dust significantly so. Conclusions Our findings support previous studies showing that exposure to coal mine dust and respirable silica leads to increased mortality from malignant and non-malignant respiratory diseases even in the absence of smoking. PMID:24186945

  19. Ten-year results of a press-fit, porous-coated acetabular component.

    PubMed

    Grobler, G P; Learmonth, I D; Bernstein, B P; Dower, B J

    2005-06-01

    We retrospectively reviewed, ten years after surgery, 100 consecutive total hip replacements in which the Duraloc 300 cup had been used. Post-operative radiographs were analysed for placement of the cup and interface gaps and follow-up radiographs for lucent lines, osteolysis, wear and migration. All the components were found to be stable with no evidence of loosening. The mean rate of wear was 0.12 mm/year. Three hips developed acetabular osteolysis at the level of the apex hole. Two have successfully undergone bone grafting without removal of the implants and one patient is awaiting surgery. The Duraloc 300 cup has a survival of 100% at ten years with no aseptic loosening and a low incidence of pelvic osteolysis. PMID:15911659

  20. Superselective radioembolization of hepatocellular carcinoma: 5-year results of a prospective study.

    PubMed

    Rösler, H; Triller, J; Baer, H U; Geiger, L; Beer, H F; Becker, C; Blumgart, L H

    1994-10-01

    Twenty patients with unresectable hepatocellular carcinoma (HCC) were followed up to 5 years after transarterial radiotherapy with 90Y-resin particles. Diagnostic radioembolizations of 99mTc-macroaggregates facilitated scintigraphic assessment of activity distribution, dose evaluation and final procedural verification. The overall survival rates were 56, 38 and 14% (after 1, 2 and 3 years, resp.). Patients with unifocal HCC and a single feeding artery (n = 7) even presented 83, 67 and 40% (2 alive after 2.75 and 4 years). With multiple arteries (n = 7), the longest survival was 26 months. Patients with multifocal HCC survived up to 33 months after selective radioembolization. Quality of life was improved in all. Survival was positively correlated with absorbed dose but residual/recurrent tumour occurred even after > or = 300 Gy. Post-treatment symptoms were minimal (35 applications), pulmonary shunt rates were correctly predicted and pulmonary complications avoided. PMID:7997379

  1. Remotely Operated Vehicles under sea ice - Experiences and results from five years of polar operations

    NASA Astrophysics Data System (ADS)

    Katlein, Christian; Arndt, Stefanie; Lange, Benjamin; Belter, Hans Jakob; Schiller, Martin; Nicolaus, Marcel

    2016-04-01

    The availability of advanced robotic technologies to the Earth Science community has largely increased in the last decade. Remotely operated vehicles (ROV) enable spatially extensive scientific investigations underneath the sea ice of the polar oceans, covering a larger range and longer diving times than divers with significantly lower risks. Here we present our experiences and scientific results acquired from ROV operations during the last five years in the Arctic and Antarctic sea ice region. Working under the sea ice means to have all obstacles and investigated objects above the vehicle, and thus changes several paradigms of ROV operations as compared to blue water applications. Observations of downwelling spectral irradiance and radiance allow a characterization of the optical properties of sea ice and the spatial variability of the energy partitioning across the atmosphere-ice-ocean boundary. Our results show that the decreasing thickness and age of the sea ice have led to a significant increase in light transmission during summer over the last three decades. Spatially extensive measurements from ROV surveys generally provide more information on the light field variability than single spot measurements. The large number of sampled ice conditions during five cruises with the German research icebreaker RV Polarstern allows for the investigations of the seasonal evolution of light transmittance. Both, measurements of hyperspectral light transmittance through sea ice, as well as classification of upward-looking camera images were used to investigate the spatial distribution of ice-algal biomass. Buoyant ice-algal aggregates were found to be positioned in the stretches of level ice, rather than pressure ridges due to a physical interaction of aggregate-buoyancy and under-ice currents. Synchronous measurements of sea ice thickness by upward looking sonar provides crucial additional information to put light-transmittance and biological observations into context

  2. Project ALERT Accomplishments by Objectives. Final Performance Report. Three-Year Results.

    ERIC Educational Resources Information Center

    Wayne State Univ., Detroit, MI. Coll. of Education.

    Project ALERT (Adult Literacy Enhanced & Redefined through Training) was a 3-year effort to develop and deploy a number of innovative approaches to delivering workplace literacy programs to business partners, including manufacturers and unions. The project designed, developed, and implemented workplace literacy programs tailored to the…

  3. Mobility of BC Transfer Students--Fall 2006 to Calendar Year 2007. Research Results

    ERIC Educational Resources Information Center

    Heslop, Joanne

    2008-01-01

    This newsletter summarizes the movement of transfer students from British Columbia (BC) colleges, university colleges, and institutes (sending Institutions) into BC universities from the Fall of 2006 into calendar year 2007. Predictions for 2008 are also provided along with trends from Fall 2003 to the present. Transfer students are classified…

  4. UAHuntsville and NASA-MSFC Heliophysics REU: Year One Strategy and Results

    NASA Astrophysics Data System (ADS)

    Farid, S.; Heerikhuisen, J.; Winebarger, A. R.

    2012-12-01

    Scientists from the University of Alabama in Huntsville and NASA Marshall Space Fight Center (MSFC) received a 3-year National Science Foundation (NSF) award to create a unique Heliophysics Research Experience for Undergraduates (REU). For 10 weeks, 10 undergraduate students engaged in cutting edge heliophysics research with NASA or UAHuntsville astrophysicists specializing in research from the solar interior to the heliopause. Research projects included theory, modeling, computer simulations, data analysis and instrument design. The primary objectives of this REU are to 1.) increase minority participation in science, technology and mathematics (STEM) fields in general, and heliophysics in particular, and 2.) decrease the STEM attrition rate in first and second year students. This REU is unique because of our focus on recruiting talented students that may not have otherwise participated in an REU. In addition to the usual criteria of most REUs, consideration of need was also given to those students who were sophomores, students with little or no previous research experience, those from small or non-PhD granting institutions, students with less than average GPA, minorities, women, etc. In this poster, we review the effectiveness of the first year strategy. We evaluate the recruitment and application process, mentor placement, living and working arrangements, introductory tutorials, and merit of final research projects. We present modifications for next year's effort, and make suggestions to similar REU programs.

  5. Hispanic Students and the Gates Millennium Scholarship Program: Promising Results Extending to the Third College Year

    ERIC Educational Resources Information Center

    Oseguera, Leticia; Denson, Nida; Hurtado, Sylvia

    2009-01-01

    Financing college is increasingly difficult for many college students and it can be especially difficult for low-income students. Using data from the Gates Millennium Scholarship Program, this study provides a portrait of the 1st and 3rd year experiences of a sample of both high achieving Hispanic scholarship recipients and non-recipients.…

  6. FINE ROOT TURNOVER IN PONDEROSA PINE STANDS OF DIFFERENT AGES: FIRST-YEAR RESULTS

    EPA Science Inventory

    Root minirhizotron tubs were installed in two ponderosa pine (Pinus ponderosa Laws.) Stands of different ages to examine patterns of root growth and death. The old-growth site (OS) consists of a mixture of old (>250 years) and young trees (ca.45 yrs)< and is located near clamp S...

  7. [Excavation in middle Iraq. Anthropologic results of findings from the thousand years before Christ].

    PubMed

    Burger-Heinrich, E

    1991-03-01

    In the years from 1970 to 1985 the "Belgian Archaeological Expedition to Iraq" excavated the remains of the ancient cultural and commercial centers Sippar and Sippar Amnanum. In connexion with this work it was possible to remove twelve human skeletons from the Persian and Hellenistic Period which are described here. PMID:1859195

  8. The Oral Proficiency Interview and the Junior Year Abroad: Some Unexpected Results.

    ERIC Educational Resources Information Center

    Veguez, Roberto

    It was found that the seemingly greatly increased oral fluency of Middlebury College seniors who had studied in college-sponsored junior year abroad programs did not carry over to written skills or to comprehensive grammatical knowledge. In the oral proficiency interview for Spanish, many returning students had no control of the subjunctive, a key…

  9. Cryogenic Storage of Cereal Grains: Results from a 20 Year Experiment

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This paper compares the viability of small grains stored under conventional (-18oC) or cryogenic conditions (vapor above liquid nitrogen(LN)) for 22 to 25 years at the National Center for Genetic Resources Preservation. Several accessions of different small grains crops were split in 1984-1987, stor...

  10. Recidivism among Child Sexual Abusers: Initial Results of a 13-Year Longitudinal Random Sample

    ERIC Educational Resources Information Center

    Patrick, Steven; Marsh, Robert

    2009-01-01

    In the initial analysis of data from a random sample of all those charged with child sexual abuse in Idaho over a 13-year period, only one predictive variable was found that related to recidivism of those convicted. Variables such as ethnicity, relationship, gender, and age differences did not show a significant or even large association with…

  11. The Effect of Placement Experience upon Final-Year Results for Surveying Degree Programmes

    ERIC Educational Resources Information Center

    Mansfield, Rachel

    2011-01-01

    It is well established that year-long industrial placements can bring workplace knowledge and increased employability. A body of recent studies has attempted to discern any effect on academic performance following the return to university, using a number of different data analysis approaches. This study discusses the difficulties of ascertaining…

  12. Jobs for America's Graduates 30th Anniversary Annual Report: Celebrating Thirty Years of Achieving Extraordinary Results!

    ERIC Educational Resources Information Center

    Jobs for America's Graduates, Inc., 2012

    2012-01-01

    Jobs for America's Graduates (JAG) is a national not-for-profit organization with a 30-year tested and proven model to cost effectively prevent school dropout among young people facing challenges of staying in school through graduation, pursuing postsecondary education and/or securing quality entry-level jobs. JAG stakeholders passionately believe…

  13. Results with SynCardia total artificial heart beyond 1 year.

    PubMed

    Torregrossa, Gianluca; Morshuis, Michiel; Varghese, Robin; Hosseinian, Leila; Vida, Vladimiro; Tarzia, Vincenzo; Loforte, Antonio; Duveau, Daniel; Arabia, Francisco; Leprince, Pascal; Kasirajan, Vigneshwa; Beyersdorf, Friedhelm; Musumeci, Francesco; Hetzer, Roland; Krabatsch, Thoamas; Gummert, Jan; Copeland, Jack; Gerosa, Gino

    2014-01-01

    Mechanical circulatory support devices have been increasingly used for long-term support. We reviewed outcomes in all patients supported with a SynCardia total artificial heart (TAH) for more than 1 year to assess its safety in long-term support. As of December 2011, all 47 patients who received the TAH from 10 centers worldwide were included in this retrospective study. Clinical data were collected on survival, infections, thromboembolic and hemorrhagic events, device failures, and antithrombotic therapy. The mean age of patients was 50 ± 1.57 years, the median support time was 554 days (range 365-1373 days). The primary diagnosis was dilated cardiomiopathy in 23 patients, ischemic in 15, and "other" in 9. After a minimum of 1 year of support, 34 patients (72%) were successfully transplanted, 12 patients (24%) died while on device support, and 1 patient (2%) is still supported. Five patients (10%) had a device failure reported. Major complications were as follows: systemic infections in 25 patients (53%), driveline infections in 13 patients (27%), thromboembolic events in 9 patients (19%), and hemorrhagic events in 7 patients (14%). SynCardia TAH has proven to be a reliable and effective device in replacing the entire heart. In patients who reached a minimum of 1 year of support, device failure rate is acceptable and only in two cases was the leading cause of death. Infections and hemorrhagic events were the major causes of death. Patients who remain supported beyond 1 year are still likely to survive to transplantation. PMID:25158888

  14. SOHO celebrates its first year in space with new results on the solar wind

    NASA Astrophysics Data System (ADS)

    1996-12-01

    hot atmosphere and its emissions into the solar system; But to fulfil its high promise, SOHO must continue operating at least until the maximum of sunspot activity around the year 2000". Joining in SOHO's anniversary greetings is Eigil Friis Christensen, a solar-terrestrial physicist at the Danish Meteorological Institute. He has played a prominent role in tracing the effects of solar variations on the terrestrial climate. "SOHO is now vital for understanding the Earth's environment", Friis Christensen says. "I am convinced that long-term changes in the strength and variability of the solar wind alter the climate, but no one knows why those changes occur. In the years ahead, as it follows the dramatic events leading from the sunspot minimum to the sunspot maximum, SOHO should reveal the processes inside the Sun that influence the character of the solar wind. If so, it will open a new chapter in solar-terrestrial climatology". Other highlights from SOHO's programme Previous ESA Information Notes (07-96 and 16-96) and photo releases have sketched SOHO's results on the solar wind and coronal mass ejections, mentioned here in connection with the LASCO, UVCS, CELIAS and SWAN instruments. The particle detectors COSTEP and ERNE have registered high-energy electrons and hydrogen and helium nuclei flung out by violent eruptions in the Sun. These particle events will become commoner as the sunspot count increases and the Sun becomes stormier. The EIT imager's many observations of the solar atmosphere by extreme ultraviolet rays have included spectacular images of tangled magnetic fields creating intense disturbances even at times when the Sun appeared extremely calm to visible-light telescopes on the ground. SOHO's ultraviolet spectrographs SUMER and CDS analyse the never-ending explosive events in the atmosphere in more detail. This is part of a concerted effort to fulfil another of SOHO's key tasks, in explaining how the Sun's atmosphere attains temperatures of millions of

  15. First Year Results from the Circumarctic Lakes Observation Network (CALON) Project

    NASA Astrophysics Data System (ADS)

    Hinkel, K. M.; Arp, C. D.; Frey, K. E.; Lenters, J. D.; Beck, R. A.; Eisner, W. R.; Gaglioti, B.; Grosse, G.; Jones, B. M.; Kim, C.; Liu, H.; Townsend-Small, A.

    2012-12-01

    -lake variability related to snow depth. Rapid warming follows ice-off, with water temperature responding synchronously to synoptic weather variations across the area. Regionally, ice-off occurs 2-4 weeks later on lakes near the coast, but with high inter-lake variability related to lake depth and area. Inland lakes are warmer in mid-summer than those near the coast, reflecting the regional climate gradient and the maritime effect. All lakes are well-mixed and largely isothermal, with some thermal stratification occurring during calm, sunny periods in deeper lakes. This project also involves measurement of carbon and nutrient dynamics and inorganic geochemistry of the lakes. Preliminary data indicate that brown colored lakes have greater dissolved methane concentrations under ice in winter than clear-water lakes, which is promising for remote sensing applications. Through a collaborative effort between the USGS-Alaska Science Center, the BLM Arctic Field Office, the NSF and other partners, we have established the Teshekpuk Lake Observatory as part of the CALON project in order to assess the past, present, and future response of Teshekpuk Lake ecosystem to environmental stressors and change. All data resulting from this 4-year project will be stored at CADIS and a specially designed web portal, and is currently accessible through the CALON web page at https://sites.google.com/a/giesn.com/nsf-calon/.

  16. Five-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Data Processing, Sky Maps, and Basic Results

    NASA Technical Reports Server (NTRS)

    Weiland, J.L.; Hill, R.S.; Odegard, 3.; Larson, D.; Bennett, C.L.; Dunkley, J.; Jarosik, N.; Page, L.; Spergel, D.N.; Halpern, M.; Meyer, S.S.; Tucker, G.S.; Wright, E.L.

    2008-01-01

    The Wilkinson Microwave Anisotropy Probe (WMAP) is a Medium-Class Explorer (MIDEX) satellite aimed at elucidating cosmology through full-sky observations of the cosmic microwave background (CMB). The WMAP full-sky maps of the temperature and polarization anisotropy in five frequency bands provide our most accurate view to date of conditions in the early universe. The multi-frequency data facilitate the separation of the CMB signal from foreground emission arising both from our Galaxy and from extragalactic sources. The CMB angular power spectrum derived from these maps exhibits a highly coherent acoustic peak structure which makes it possible to extract a wealth of information about the composition and history of the universe. as well as the processes that seeded the fluctuations. WMAP data have played a key role in establishing ACDM as the new standard model of cosmology (Bennett et al. 2003: Spergel et al. 2003; Hinshaw et al. 2007: Spergel et al. 2007): a flat universe dominated by dark energy, supplemented by dark matter and atoms with density fluctuations seeded by a Gaussian, adiabatic, nearly scale invariant process. The basic properties of this universe are determined by five numbers: the density of matter, the density of atoms. the age of the universe (or equivalently, the Hubble constant today), the amplitude of the initial fluctuations, and their scale dependence. By accurately measuring the first few peaks in the angular power spectrum, WMAP data have enabled the following accomplishments: Showing the dark matter must be non-baryonic and interact only weakly with atoms and radiation. The WMAP measurement of the dark matter density puts important constraints on supersymmetric dark matter models and on the properties of other dark matter candidates. With five years of data and a better determination of our beam response, this measurement has been significantly improved. Precise determination of the density of atoms in the universe. The agreement between

  17. New Jersey Statewide Minimum Standards: Results from the Program's Fourth Year. Occasional Pepers in Education.

    ERIC Educational Resources Information Center

    Gallas, Howard B.

    The New Jersey Minimum Basic Skills (MBS) Tests in reading and mathematics were administered for the third consecutive year during the week of March 24, 1980 to approximately 390,000 publicly educated students in grades 3, 6, 9, and 11. The 1979-80 MBS Tests measured the same skills as the 1977-78 and 1978-79 tests. These three tests remained…

  18. One-year follow-up results of the STARS for Families alcohol prevention program.

    PubMed

    Werch, C E; Owen, D M; Carlson, J M; DiClemente, C C; Edgemon, P; Moore, M

    2003-02-01

    This study examined the 1-year follow-up effects of the STARS (Start Taking Alcohol Risks Seriously) for Families program, a 2-year preventive intervention based on a stage of acquisition model, and consisting of nurse consultations and parent materials. A randomized controlled trial was conducted, with participants receiving either the intervention or a minimal intervention control. Participants included a cohort of 650 sixth-grade students from two urban middle schools-one magnet (bused) and one neighborhood. Trained project staff administered questionnaires to students following a standardized protocol in the schools. For the magnet school sample, significantly fewer intervention students (5%) were planning to drink in the next 6 months than control students (18%), chi2 = 11.53, 1 d.f., P = 0.001. Magnet school intervention students also had less intentions to drink in the future, greater motivation to avoid drinking and less total alcohol risk than control students, Ps < 0.05. For the neighborhood school, intervention students (m = 7.90, SD = 1.87) had less total alcohol risk than control students (m = 8.42, SD = 1.83), F(1,205) = 4.09, P = 0.04. These findings suggest that a brief, stage and risk/protective factor tailored program holds promise for reducing risk for alcohol use among urban school youth 1 year after intervention, and has the unique advantage of greater 'transportability' over classroom-based prevention programs. PMID:12608685

  19. Aquarius Satellite Salinity Measurement Mission Status, and Science Results from the initial 3-Year Prime Mission

    NASA Astrophysics Data System (ADS)

    Lagerloef, G. S. E.; Kao, H. Y.

    2014-12-01

    The Aquarius satellite microwave sensor, launched June 2011, as part of the US-Argentina joint Aquarius/SAC-D mission, and commenced observations on 25 Aug2011, and completed three years of ocean surface salinity measurements in late August 2014. The Aquarius measurement objectives are to describe unknown features in the sea surface salinity (SSS) field, and document seasonal and interannual variations on regional and basin scales. This presentation will first describe the structure of the mean annual global salinity field compared with the previous in situ climatology and contemporary in situ measurements , including small persistent biases of opposite sign in high latitudes versus low latitudes, currently under intense investigation, as well as global and regional error statistics. Then we summarize highlights of various studies and papers submitted to the JGR-Oceans special section on satellite salinity (2014). The most prominent seasonal variations, most notably the extant and variability of the SSS signature of the Atlantic and Pacific inter-tropical convergence zones, Amazon-Orinoco and other major rivers, and other important regional patterns of seasonal variability. Lastly we will examine the trends observed during the three Sep-Aug measurement years beginning Sep2011, Sep2012 and Sep2013, respectively, in relation to ENSO and other climate indices, as the first step in analyzing interannual SSS variability. An outline for extended mission operations beyond the initial three-year prime mission will be presented.

  20. French brain tumor database: 5-year histological results on 25 756 cases.

    PubMed

    Rigau, Valérie; Zouaoui, Sonia; Mathieu-Daudé, Hélène; Darlix, Amélie; Maran, Aurélie; Trétarre, Brigitte; Bessaoud, Faiza; Bauchet, Fabienne; Attaoua, Redha; Fabbro-Peray, Pascale; Fabbro, Michel; Kerr, Christine; Taillandier, Luc; Duffau, Hugues; Figarella-Branger, Dominique; Costes, Valérie; Bauchet, Luc

    2011-11-01

    This work aimed to prospectively record all primary central nervous system tumor (PCNST) cases in France, for which histological diagnosis is available. The objectives were to (i) create a national registry and a network to perform epidemiological studies; (ii) implement clinical and basic research protocols; and (iii) harmonize the health care of patients affected by PCNST. For 5 years, 25 756 cases of newly diagnosed and histologically confirmed PCNST have been recorded. Histological diagnoses included glioma (48.9%), all other neuroepithelial tumors (5%), meningioma (28.8%), nerve sheath tumors (8.4%), lymphoma (3.2%) and others (5.7%). Cryopreservation was reported for 6018 PCNST specimens. Tumor resections (R) were performed in 78% cases, while biopsies accounted for 22%. Median age (MA), sex, percentage R and number of cryopreserved tumors were detailed for each histology; for example, out of 6053 glioblastomas (MA 63 years, male 59.4%, R 62%, 1611 were cryopreserved), and out of 37 atypical teratoid/rhabdoid tumors (MA 2 years, male 56.8%, R 94%, 17 were cryopreserved). This database or databank dedicated to PCNST cases contains detailed data on clinical, histological and other characteristics, such as the inclusion of data on cryopreserved specimens that are not available in other European registries. Therefore, this is a valuable resource that can be used for planning future epidemiological and clinical research. PMID:21554472

  1. Eight-year results of site retention of anorganic bovine bone and anorganic bovine matrix.

    PubMed

    Degidi, Marco; Perrotti, Vittoria; Piattelli, Adriano; Iezzi, Giovanna

    2013-12-01

    The long-term fate of some biomaterials is still unknown, and the reports present in the literature are not conclusive as to whether these biomaterials are resorbed over time or not. Different reports can be found with regard to the resorption behavior of anorganic bovine bone (ABB). The aim of the present study was to provide a comparative histological and histomorphometrical evaluation, in the same patient, of 2 specimens retrieved from a sinus augmented with ABB and with anorganic bovine matrix added to a cell-binding peptide (PepGen P-15), respectively, after a healing period of 6 months and after 8 years of implant loading, to evaluate the resorption of both biomaterials. A unilateral sinus augmentation procedure with ABB (50%) and with PepGen P-15 (50%) was performed in a 54-year-old male patient. Two titanium dental implants with a sandblasted and acid-etched surface were inserted after 6 months. During this procedure, 2 tissue cores were retrieved from the sinus with a trephine, before implant insertion. After an additional 6 months, a fixed prosthetic restoration was fabricated. One of these implants, after a loading period of 8 years, fractured in the coronal portion and was removed. Both specimens, one retrieved after a 6-month healing period and the other after an 8-year loading period, were treated to obtain thin ground sections. In the 6-month specimen, the histomorphometry showed that the percentage of newly formed bone was 27.2% ± 3.6%, marrow spaces 35.6% ± 2.3%, residual ABB particles 25.1% ± 1.2%, and residual PepGen P-15 particles 12.1% ± 2.2%. In the 8-year specimen, the histomorphometry showed that the percentage of newly formed bone was 51.4% ± 4.8%, marrow spaces 40% ± 7.1%, residual ABB particles 6.2% ± 0.7%, and residual PepGen P-15 particles 2.4% ± 0.5%. Both biomaterials underwent significant resorption over the course of this study. PMID:22103882

  2. Nine-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Cosmological Parameter Results

    NASA Technical Reports Server (NTRS)

    Hinshaw, G.; Larson, D.; Komatsu, E.; Spergel, D. N.; Bennett, C. L.; Dunkley, J.; Nolta, M. R.; Halpern, M.; Hill, R. S.; Odegard, N.; Page, L.; Smith, K. L.; Weiland, J. L.; Gold, B.; Jarosik, N.; Kogut, A.; Limon, M.; Meyer, S. S.; Tucker, G. S.; Wollack, E.; Wright, E. L.

    2013-01-01

    We present cosmological parameter constraints based on the final nine-year Wilkinson Microwave Anisotropy Probe (WMAP) data, in conjunction with a number of additional cosmological data sets. The WMAP data alone, and in combination, continue to be remarkably well fit by a six-parameter Lambda-CDM model. When WMAP data are combined with measurements of the high-l cosmic microwave background anisotropy, the baryon acoustic oscillation scale, and the Hubble constant, the matter and energy densities Omega(sub b)h(exp 2), Omega(sub c)h(exp 2)and Omega(sub Lambda), are each determined to a precision of approx. 1.5%. The amplitude of the primordial spectrum is measured to within 3%, and there is now evidence for a tilt in the primordial spectrum at the 5 sigma level, confirming the first detection of tilt based on the five-year WMAP data. At the end of the WMAP mission, the nine-year data decrease the allowable volume of the six-dimensional Lambda-CDM parameter space by a factor of 68,000 relative to pre-WMAP measurements. We investigate a number of data combinations and show that their Lambda-CDM parameter fits are consistent. New limits on deviations from the six-parameter model are presented, for example: the fractional contribution of tensor modes is limited to r < 0.13 (95% CL); the spatial curvature parameter is limited to Omega(sub kappa) = (0.0027 (sub +0.0039) (sup -0.0038;) the summed mass of neutrinos is limited to Sigma M(sub nu) < 0.44 eV (95% CL); and the number of relativistic species is found to lie within N(sub eff) = 3.84 +/- 0+/-40, when the full data are analyzed. The joint constraint on N(sub eff) and the primordial helium abundance, Y(sub He), agrees with the prediction of standard big bang nucleosynthesis. We compare recent Planck measurements of the Sunyaev-Zel'dovich effect with our seven-year measurements, and show their mutual agreement. Our analysis of the polarization pattern around temperature extrema is updated. This confirms a fundamental

  3. Emulytics for Cyber-Enabled Physical Attack Scenarios: Interim LDRD Report of Year One Results.

    SciTech Connect

    Clem, John; Urias, Vincent; Atkins, William Dee; Symonds, Christopher J.

    2015-12-08

    Sandia National Laboratories has funded the research and development of a new capability to interactively explore the effects of cyber exploits on the performance of physical protection systems. This informal, interim report of progress summarizes the project’s basis and year one (of two) accomplishments. It includes descriptions of confirmed cyber exploits against a representative testbed protection system and details the development of an emulytics capability to support live, virtual, and constructive experiments. This work will support stakeholders to better engineer, operate, and maintain reliable protection systems.

  4. Treatment performances of French constructed wetlands: results from a database collected over the last 30 years.

    PubMed

    Morvannou, A; Forquet, N; Michel, S; Troesch, S; Molle, P

    2015-01-01

    Approximately 3,500 constructed wetlands (CWs) provide raw wastewater treatment in France for small communities (<5,000 people equivalent). Built during the past 30 years, most consist of two vertical flow constructed wetlands (VFCWs) in series (stages). Many configurations exist, with systems associated with horizontal flow filters or waste stabilization ponds, vertical flow with recirculation, partially saturated systems, etc. A database analyzed 10 years earlier on the classical French system summarized the global performances data. This paper provides a similar analysis of performance data from 415 full-scale two-stage VFCWs from an improved database expanded by monitoring data available from Irstea and the French technical department. Trends presented in the first study are confirmed, exhibiting high chemical oxygen demand (COD), total suspended solids (TSS) and total Kjeldahl nitrogen (TKN) removal rates (87%, 93% and 84%, respectively). Typical concentrations at the second-stage outlet are 74 mgCOD L(-1), 17 mgTSS L(-1) and 11 mgTKN L(-1). Pollutant removal performances are summarized in relation to the loads applied at the first treatment stage. While COD and TSS removal rates remain stable over the range of applied loads, the spreading of TKN removal rates increases as applied loads increase. PMID:25945849

  5. Maintenance requirements associated with mandibular implant overdentures: clinical results after first year of service.

    PubMed

    Bilhan, Hakan; Geckili, Onur; Mumcu, Emre; Bilmenoglu, Caglar

    2011-12-01

    The aim of this clinical study was to evaluate the prosthodontic maintenance requirements during the first year of service of mandibular overdentures supported by interforaminal implants and to assess the influence of attachment type, implant number, and bite force on these requirements. Fifty-nine patients treated with mandibular implant overdentures between the years 2004 and 2009 and appearing in the 12th-month recall were included in this study. The overdentures constituted 4 groups: 2 single interforaminal implants (1 group with locator and 1 group with ball attachments), 3 single interforaminal implants, 3 splinted interforaminal implants (bar), and 4 splinted interforaminal implants (bar). During the examination, prosthetic parameters such as occlusion, tissue adaptation, condition of the retentive mechanism (matrice and patrice), and the condition of the denture-bearing tissues were evaluated and recorded. No statistically significant relation was found between attachment type, bite force values, implant number, and the occurring complications except the need for relining, which was found significantly more in the ball attachments than in other attachment groups (P  =  .03). After 12 months following the overdenture insertion, there seems to be no relation between occurring complications and patient-related factors, such as maximum bite force, age, and gender, as well as factors related to the overdentures such as number and type of attachments. PMID:20932124

  6. The relationship between clinical periodontal status and insulin-dependent diabetes mellitus. Results after 5 years.

    PubMed

    Firatli, E

    1997-02-01

    The clinical periodontal status of 44 insulin-dependent diabetic children and adolescents and 20 healthy control subjects was compared for a period of approximately 5 years. Fasting blood glucose, fructosamine, and glycosylated hemoglobin (HbA1) values were determined at baseline and 5 years later. The differences in the clinical and laboratory parameters were compared during the study period. The differences between the two groups were also evaluated. The only statistically significant difference observed in the diabetic group was clinical attachment loss (CAL). The CAL was statistically significantly higher in the diabetic group compared to the controls, and a statistically significantly higher in the diabetic group compared to the controls, and a statistically significant positive correlation was observed between the duration of diabetes and CAL. Fructosamine was also correlated with the gingival index in the diabetic group while there was no correlation in the controls. It may be concluded that diabetes modifies the clinical status of the periodontal tissues and increases clinical attachment loss. PMID:9058330

  7. Building upon the Electronic Geophysical Year (eGY) Experience: Transitioning Research Results to Operations (Invited)

    NASA Astrophysics Data System (ADS)

    Baker, D.

    2009-12-01

    The past 15 years have seen the development of many cost effective ways to acquire, store, and exchange data. We have the potential to expand the exchange of data by allowing working scientists and operational agencies to access and manipulate information and models from large interdisciplinary centers as well as from small, previously isolated, research groups. The key to this technology requires adoption of community-developed standards for data storage and description to form an ''Informatics Commons.'' Scientific societies currently promote the establishment of a system of Virtual Observatories. The Electronic Geophysical Year (eGY) concept (2007-2008) embraced all available and upcoming geophysical data (e.g., atmospheric, geomagnetic, ionospheric, magnetospheric, etc.) and advocated organizing them into a series of virtual geophysical observatories deployed in cyberspace. This concept allows access to all available data through the Internet and World Wide Web, taking advantage of existing networking hardware and software technologies (e.g., Internet, XML, Service-Oriented Architectures, Semantic Web, etc.). The eGY provided an international focus for a resolve to address the issues of data release, data discovery, and data preservation. This effort can help revolutionize the transition of basic research to a state of operational readiness.

  8. Four Years of Practical Arrangements between IAEA and Moscow SIA 'Radon': Preliminary Results - 13061

    SciTech Connect

    Batyukhnova, O.G.; Karlina, O.K.; Neveikin, P.P.

    2013-07-01

    The International Education Training Centre (IETC) at Moscow State Unitary Enterprise Scientific and Industrial Association 'Radon' (SIA 'Radon'), in co-operation with the International Atomic Energy Agency (IAEA), has developed expertise and provided training to waste management personnel for the last 15 years. Since 1997, the educational system of the enterprise with the support of the IAEA has acquired an international character: more than 470 experts from 35 countries- IAEA Member States completed the professional development. Training is conducted at various thematic courses or fellowships for individual programs and seminars on IAEA technical projects. In June 2008 a direct agreement (Practical Arrangements) was signed between SIA 'Radon' and the IAEA on cooperation in the field of development of new technologies, expert's advice to IAEA Member States, and, in particular, the training of personnel in the field of radioactive waste management (RWM), which opens up new perspectives for fruitful cooperation of industry professionals. The paper summarizes the current experience of the SIA 'Radon' in the organization and implementation of the IAEA sponsored training and others events and outlines some of strategic educational elements, which IETC will continue to pursue in the coming years. (authors)

  9. 76 FR 4865 - Purified Carboxymethylcellulose From Mexico: Final Results of the First Five-Year (“Sunset...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... Results of the First Five-year (``Sunset'') Review of Antidumping Duty Order, 75 FR 60084 (September 29...) of the Act. See Preliminary Results, 75 FR 60084. In our Preliminary Results, we found that... Review We have made no changes to our Preliminary Results, 75 FR 60084. We continue to find...

  10. Main results of the work accomplished at ZAO Interavtomatika for 15 years

    NASA Astrophysics Data System (ADS)

    Lysko, V. V.; Sviderskii, A. G.; Bilenko, V. A.; Anan'ev, A. A.

    2008-10-01

    Main results of the activities carried out by ZAO Interavtomatika in the Russian market of power engineering are presented. Main lines of activities are described, the results of putting in use control systems are analyzed, and prospects for their further development are presented.

  11. Treatment of contained lumbar disc herniations using radiofrequency assisted micro-tubular decompression and nucleotomy: four year prospective study results

    PubMed Central

    2014-01-01

    Background Patients with radiculopathy caused by contained disc herniations are less likely to have good outcomes following discectomy surgery than patients with disc herniations that are not contained. The author presents his 4-year results from a prospective trial regarding the efficacy and safety of a tubular transforaminal radiofrequency-assisted manual decompression and annulus modulation of contained disc herniations in 58 patients. Methods Fifty-eight patients with lumbar radiculopathy due to a contained disc herniation were enrolled in a prospective clinical study. Visual analog scores (VAS) for back pain and leg pain, quality of life assessment, Macnab criteria, and SF-12 were collected from patients before treatment, at 2-years and 4-years post-treatment. Results At 4 years, results were obtained from 47 (81%) of patients. Compared to mean pre- treatment assessments, mean 4-year VAS for back pain improved from 8.6 to 2.3 points, and mean VAS for leg pain improved from 7.8 to 2.3. Eighty-three percent of respondents reported that they were “satisfied” or “very satisifed” with their quality of life at 4-years as per SF-12. At 4 years, recurrence was noted in 3 (6.4%) of respondents and no complications were reported. Conclusions The 2-year and 4-year study results are nearly identical, suggesting durable benefit out to 4 years. These results also suggest that in carefully selected patients with sustained contained disc herniations who have failed conservative treatments, manual decompression combined with radiofrequency-assisted decompression and annulus modulation are very likely to have good outcomes 4 years post-treatment. PMID:25694932

  12. Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years.

    PubMed

    Tapaltsyan, Vagan; Eronen, Jussi T; Lawing, A Michelle; Sharir, Amnon; Janis, Christine; Jernvall, Jukka; Klein, Ophir D

    2015-05-01

    The fossil record is widely informative about evolution, but fossils are not systematically used to study the evolution of stem-cell-driven renewal. Here, we examined evolution of the continuous growth (hypselodonty) of rodent molar teeth, which is fuelled by the presence of dental stem cells. We studied occurrences of 3,500 North American rodent fossils, ranging from 50 million years ago (mya) to 2 mya. We examined changes in molar height to determine whether evolution of hypselodonty shows distinct patterns in the fossil record, and we found that hypselodont taxa emerged through intermediate forms of increasing crown height. Next, we designed a Markov simulation model, which replicated molar height increases throughout the Cenozoic and, moreover, evolution of hypselodonty. Thus, by extension, the retention of the adult stem cell niche appears to be a predictable quantitative rather than a stochastic qualitative process. Our analyses predict that hypselodonty will eventually become the dominant phenotype. PMID:25921530

  13. National Institutes of Health phase I, Small Business Innovation Research applications: fiscal year 1983 results.

    PubMed

    Vener, K J

    1985-08-01

    A review of the 356 disapproved Small Business Innovation Research (SBIR) proposals submitted to the National Institutes of Health (NIH) for fiscal year 1983 funding was undertaken to identify the most common shortcomings of those disapproved applications. The shortcomings were divided into four general classes by using the scheme developed by other authors when describing the reasons for the disapproval of regular NIH research applications. Comparison of the reasons for disapproval of SBIR applications with regular applications suggests comparable difficulties in the areas of the problem and the approach. There is some indication, however, that the SBIR proposals may have been weaker in the category of the principal investigator (PI). In general, it is the responsibility of the PI to demonstrate that the work is timely and can be performed with available technology and expertise, and that the guidelines for the NIH SBIR program have been satisfied. PMID:4018273

  14. Central venous catheters for chemotherapy of solid tumors--our results in the last 5 years.

    PubMed

    Zganjer, Mirko; Cizmić, Ante; Butković, Diana; Matolić, Martina; Karaman-Ilić, Maja; Stepan, Jasminka

    2008-09-01

    Central venous catheters provide an easy access for intravenous medications. Having a central line in place will relieve a child from the discomfort and danger of multiple regular intravenous lines for chemotherapy. The use of indwelling central venous catheters has become commonplace in the management of children undergoing oncological treatment. There are two types of central lines commonly used. There are Broviac catheters and Port-A-Cath (PAC) catheters. In the last 5 years we inserted 194 catheters in 175 children. We inserted 121 Broviac catheters and 73 PAC catheters. During the follow up of 39382 catheter days 44 complications were observed. In Broviac group the median follow up was 155 days and in PAC group was 230 days. We observed differences in the incidence between two devices. In Broviac group infections were more frequent and in PAC group other complications were more frequent than infections. PMID:18982750

  15. Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years

    PubMed Central

    Mushegyan, Vagan; Eronen, Jussi T.; Lawing, A. Michelle; Sharir, Amnon; Janis, Christine; Jernvall, Jukka; Klein, Ophir D.

    2015-01-01

    Summary The fossil record is widely informative about evolution, but fossils are not systematically used to study the evolution of stem cell-driven renewal. Here, we examined evolution of the continuous growth (hypselodonty) of rodent molar teeth, which is fuelled by the presence of dental stem cells. We studied occurrences of 3500 North American rodent fossils, ranging from 50 million years ago (mya) to 2 mya. We examined changes in molar height to determine if evolution of hypselodonty shows distinct patterns in the fossil record, and we found that hypselodont taxa emerged through intermediate forms of increasing crown height. Next, we designed a Markov simulation model, which replicated molar height increases throughout the Cenozoic, and, moreover, evolution of hypselodonty. Thus, by extension, the retention of the adult stem-cell niche appears to be a predictable quantitative rather than a stochastic qualitative process. Our analyses predict that hypselodonty will eventually become the dominant phenotype. PMID:25921530

  16. Observing Global Ocean Circulation From Space: The First Year's Results From the TOPEX/POSEIDON Mission

    NASA Technical Reports Server (NTRS)

    Fu, L. -L.

    1993-01-01

    The joint U.S./France TOPEX/Poseidon satellite was launched on August 10, 1992, and became operational 43 days later. The major goal of the mission is to use a radar altimeter system for making precise measurements of the height of the sea surface for the study of the dynamics of large-scale ocean circulation, which is a key to understanding global climate change. Additionally, the data are used for studying ocean tides and marine geophysics. The radar altimeter also measures wave height and wind speed. The mission is being conducted to optimize the sea surface height measurements for a minimum of three years. The primary objective of the first six months of the mission was to calibrate and validate the mission's measurements...

  17. RTT150 Planet Search Program at TUG: Results from Seven Years of Observation

    NASA Astrophysics Data System (ADS)

    Yılmaz, M.; Selam, S. O.; Izumiura, H.; Bikmaev, I.; Sato, B.; Keskin, V.; Kambe, E.

    2015-07-01

    We have carried out a precise Doppler survey of evolved intermediate-mass stars at the TÜBİTAK National Observatory (TUG) since 2007 in order to detect planetary systems around these stars. For the past seven years we have been monitoring the radial velocity (RV) of 50 G-K type giants with a Doppler precision of 10 m s-1, using the Coude Echelle Spectrograph (CES) equipped with an iodine absorption cell. We have found that 9 stars show significant RV variations between 1 and 8 km s-1, while 13 targets have RV variation of 20-500 m s-1. The rest of the targets have a RV scatter of 10 m s-1. We have also found that several candidates show significant periodic RV variations that may imply the presence of stellar or substellar companions.

  18. Early identification of cognitive impairment and dementia: Results from four years of the community consultation center.

    PubMed

    Ishiwata, Akiko; Kitamura, Shin; Nomura, Toshiaki; Nemoto, Rumi; Ishii, Chika; Wakamatsu, Naoki; Katayama, Yasuo

    2014-01-01

    The community consultation center was established as the core facility for a project entitled "Community Support Network for Citizens with Mild Cognitive Impairment (MCI) and Dementia." This study reports on our center's activity and user outcomes. Users consulted with medical staff regarding their memory problems and were self-screened using a touch-panel computer assisted screening tool (TPST). Dementia was suspected when the TPST score was 12 points or below, and the Mini-Mental State Examination (MMSE) was conducted by our onsite clinical psychologists, which served as the gold standard. All reports were provided to user's primary care physicians, or a nearby medical institute if users did not have a primary care physician. Patient outcomes were obtained from participating medical institutes. Informed consent was obtained for all users. In the four-year period, 2802 users visited the center. Of them, 1565 registered (men/women=519/1046; mean age, 74 years). Of 1354 people who used TPST, 622 (45.9%) scored 12 points or below. 409 confirmed diagnoses from the medical institutes revealed MCI in 11.2%, Alzheimer's disease in 37.1%, and vascular dementia in 8.0%. Among the 207 users who had no primary care physicians at consultation, 43 (20.8%) were diagnosed with MCI or dementia. Approximately half of the users who took the TPST were suspected of dementia following interview by a clinical psychologist. Both MCI and dementia were confirmed by the medical institutes in 59.6% of users. We conclude that our consultation center plays a pivotal role in early diagnosis of MCI and dementia. PMID:25022712

  19. The DOTS strategy in China: results and lessons after 10 years.

    PubMed Central

    Xianyi, Chen; Fengzeng, Zhao; Hongjin, Duanmu; Liya, Wan; Lixia, Wang; Xin, Du; Chin, Daniel P.

    2002-01-01

    OBJECTIVE: To analyse the five-point tuberculosis (TB) strategy, DOTS, 10 years after its implementation in one-half of China's population, and to suggest lessons for future implementation of the DOTS strategy. METHODS: We analysed trends in case-finding and treatment outcome over time following implementation of the DOTS strategy in each county, using routine reporting data from the Infectious and Endemic Disease Control (IEDC) project (1991 - 2000). We also determined the proportion of counties with different levels of case-finding for the fifth and sixth years of DOTS implementation. FINDINGS: From 1991 to 1995, DOTS expanded rapidly to cover more than 90% of target population and counties. By 2000, 8 million TB suspects had received free diagnostic evaluation: 1.8 million TB cases were diagnosed, free treatment was provided to 1.3 million smear-positive cases, and more than 90% were cured. During DOTS implementation, the percentage of previously treated cases decreased among all smear-positive cases and treatment outcomes improved. Despite these achievements, the detection rate for new smear-positive cases in the project was estimated to be only 54% in 1998, and 41.2% of the counties had a below average or low level of case-finding (with substantial variation between provinces). CONCLUSIONS: The IEDC project demonstrated that it is feasible to rapidly expand DOTS on a large scale. The global target of an 85% cure rate was quickly achieved, and the level of drug-resistance was probably reduced by this project. However, case-detection did not reach the 70% global target, and more research is needed on how to enhance this. PMID:12131998

  20. Improved 6-year overall survival in AT/RT - results of the registry study Rhabdoid 2007.

    PubMed

    Bartelheim, Kerstin; Nemes, Karolina; Seeringer, Angela; Kerl, Kornelius; Buechner, Jochen; Boos, Joachim; Graf, Norbert; Dürken, Matthias; Gerss, Joachim; Hasselblatt, Martin; Kortmann, Rolf-Dieter; Teichert von Luettichau, Irene; Nagel, Inga; Nygaard, Randi; Oyen, Florian; Quiroga, Eduardo; Schlegel, Paul-Gerhardt; Schmid, Irene; Schneppenheim, Reinhard; Siebert, Reiner; Solano-Paez, Palma; Timmermann, Beate; Warmuth-Metz, Monika; Frühwald, Michael Christoph

    2016-08-01

    Atypical teratoid rhabdoid tumors (AT/RT) are characterized by mutations and subsequent inactivation of SMARCB1 (INI1, hSNF5), a predilection for very young children and an unfavorable outcome. The European Registry for rhabdoid tumors (EU-RHAB) was established to generate a common European database and to establish a standardized treatment regimen as the basis for phase I/II trials. Thus, genetic analyses, neuropathologic and radiologic diagnoses, and a consensus treatment regimen were prospectively evaluated. From 2005 to 2009, 31 patients with AT/RT from four countries were recruited into the registry study Rhabdoid 2007 and treated with systemic and intraventricular chemotherapy. Eight patients received high-dose chemotherapy, 23 radiotherapy, and 17 maintenance therapy. Reference evaluations were performed in 64% (genetic analyses, FISH, MLPA, sequencing) up to 97% (neuropathology, INI1 stain). Germ-line mutations (GLM) were detected in 6/21 patients. Prolonged overall survival was associated with age above 3 years, radiotherapy and achievement of a complete remission. 6-year overall and event-free survival rates were 46% (±0.10) and 45% (±0.09), respectively. Serious adverse events and one treatment-related death due to insufficiency of a ventriculo peritoneal shunt (VP-shunt) and consecutive herniation were noted. Acquisition of standardized data including reference diagnosis and a standard treatment schedule improved data quality along with a survival benefit. Treatment was feasible with significant but manageable toxicity. Although our analysis is biased due to heterogeneous adherence to therapy, EU-RHAB provides the best available basis for phase I/II clinical trials. PMID:27228363

  1. [Analysis of the results of the SEIMC External Quality Control Program. Year 2014].

    PubMed

    Gopegui Bordes, Enrique Ruiz de; Guna Serrano, M Del Remedio; Orta Mira, Nieves; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2016-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2014 controls. As a whole, the results obtained in 2014 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of the SEIMC program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests. PMID:27474240

  2. [Analysis of the results of the SEIMC External Quality Control Program. Year 2013].

    PubMed

    de Gopegui Bordes, Enrique Ruiz; Orta Mira, Nieves; Del Remedio Guna Serrano, M; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2015-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, molecular microbiology and HIV-1, HCV and HBV viral loads. This manuscript presents the analysis of results obtained of the participants from the 2013 SEIMC External Quality Control Programme, except viral loads controls, that they are summarized in a manuscript abroad. As a whole, the results obtained in 2013 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests. PMID:26320989

  3. One-year results of cemented bipolar radial head prostheses for comminuted radial head fractures

    PubMed Central

    Laun, Reinhold; Wild, Michael; Hakimi, Mohssen

    2015-01-01

    Introduction: Comminuted radial head fractures (Mason type III) continue to pose a challenge to orthopedic surgeons. When internal fixation is not possible, radial head arthroplasty has been advocated as the treatment of choice. The purpose of this retrospective study was to evaluate clinical and radiological short-term results of patients with Mason type III radial head fractures treated with a cemented bipolar radial prosthesis. Methods: Twelve patients received cemented bipolar radial head hemiarthroplasty for comminuted radial head fractures. In all patients a CT scan was obtained prior to surgical treatment to assess all associated injuries. Postoperatively an early motion protocol was applied. All patients were evaluated clinically and radiologically at an average of 12.7 months. Results: According to the Mayo Modified Wrist Score, the Mayo Elbow Performance Score, the functional rating index of Broberg and Morrey, and the DASH Score good to excellent results were obtained. Grip strength and range of motion were almost at the level of the unaffected contralateral side. Patient satisfaction was high, no instability or signs of loosening of the implant, and only mild signs of osteoarthritis were seen. Conclusion: Overall good to excellent short-term results for primary arthroplasty for comminuted radial head fractures were observed. These encouraging results warrant the conduction of further studies with long-term follow-up and more cases to see if these short-term results can be maintained over time. PMID:26734534

  4. Year One Results from the Multisite Randomized Evaluation of the i3 Scale-Up of Reading Recovery

    ERIC Educational Resources Information Center

    May, Henry; Gray, Abigail; Sirinides, Philip; Goldsworthy, Heather; Armijo, Michael; Sam, Cecile; Gillespie, Jessica N.; Tognatta, Namrata

    2015-01-01

    Reading Recovery (RR) is a short-term, one-to-one intervention designed to help the lowest achieving readers in first grade. This article presents first-year results from the multisite randomized controlled trial (RCT) and implementation study under the $55 million Investing in Innovation (i3) Scale-Up Project. For the 2011-2012 school year, the…

  5. Summary of Mode Deactivation Therapy, Cognitive Behavior Therapy and Social Skills Training with Two Year Post Treatment Results

    ERIC Educational Resources Information Center

    Apsche, Jack A.; Bass, Christopher K.; Siv, Alexander M.

    2006-01-01

    This study summarized two treatment research studies and included recidivism data for two years post discharge for group therapy. The study compared Mode deactivation Therapy (MDT), Cognitive Behavior Therapy (CBT), and Social Skills training (SST), results of the MDT series of studies and the two year post-study recidivism data. The data from the…

  6. Everolimus and Early Calcineurin Inhibitor Withdrawal: 3-Year Results From a Randomized Trial in Liver Transplantation

    PubMed Central

    Sterneck, M; Kaiser, G M; Heyne, N; Richter, N; Rauchfuss, F; Pascher, A; Schemmer, P; Fischer, L; Klein, C G; Nadalin, S; Lehner, F; Settmacher, U; Neuhaus, P; Gotthardt, D; Loss, M; Ladenburger, S; Paulus, E M; Mertens, M; Schlitt, H J

    2014-01-01

    The feasibility of de novo everolimus without calcineurin inhibitor (CNI) therapy following liver transplantation was assessed in a multicenter, prospective, open-label trial. Liver transplant patients were randomized at 4 weeks to start everolimus and discontinue CNI, or continue their current CNI-based regimen. The primary endpoint was adjusted estimated GFR (eGFR; Cockcroft-Gault) at month 11 postrandomization. A 24-month extension phase followed 81/114 (71.1%) of eligible patients to month 35 postrandomization. The adjusted mean eGFR benefit from randomization to month 35 was 10.1 mL/min (95% confidence interval [CI] −1.3, 21.5 mL/min, p = 0.082) in favor of CNI-free versus CNI using Cockcroft-Gault, 9.4 mL/min/1.73 m2 (95% CI −0.4, 18.9, p = 0.053) with Modification of Diet in Renal Disease (four-variable) and 9.5 mL/min/1.73 m2 (95% CI −1.1, 17.9, p = 0.028) using Nankivell. The difference in favor of the CNI-free regimen increased gradually over time due to a small progressive decline in eGFR in the CNI cohort despite a reduction in CNI exposure. Biopsy-proven acute rejection, graft loss and death were similar between groups. Adverse events led to study drug discontinuation in five CNI-free patients and five CNI patients (12.2% vs. 12.5%, p = 1.000) during the extension phase. Everolimus-based CNI-free immunosuppression is feasible following liver transplantation and patients benefit from sustained preservation of renal function versus patients on CNI for at least 3 years. The beneficial effect on renal function achieved by early CNI withdrawal and treatment with everolimus after liver transplantation is still evident after three years. PMID:24502384

  7. Five-Year ALARA Review of Dosimetry Results 1 January 2010 through 31 December 2014.

    SciTech Connect

    Paulus, Luke R.

    2015-06-01

    A review of dosimetry results from 1 January 2010 through 31 December 2014 was conducted to demonstrate that radiation protection methods used are compliant with regulatory limits and conform to the philosophy to keep exposures to radiation As Low As is Reasonably Achievable (ALARA). This included a review and evaluation of personnel dosimetry (external and internal) results at Sandia National Laboratories, New Mexico as well as at Sandia National Laboratories, California. Additionally, results of environmental monitoring efforts at Sandia National Laboratories, New Mexico were reviewed. ALARA is a philosophical approach to radiation protection by managing and controlling radiation exposures (individual and collective) to the work force and to the general public to levels that are As Low As is Reasonably Achievable taking social, technical, economic, practical, and public policy considerations into account. ALARA is not a dose limit but a process which has the objective of attaining doses as far below applicable dose limits As Low As is Reasonably Achievable.

  8. Five-Year ALARA Review of Dosimetry Results 1 January 2009 through 31 December 2013.

    SciTech Connect

    Paulus, Luke R

    2014-08-01

    A review of dosimetry results from 1 January 2009 through 31 December 2013 was conducted to demonstrate that radiation protection methods used are compliant with regulatory limits and conform to the ALARA philosophy. This included a review and evaluation of personnel dosimetry (external and internal) results at Sandia National Laboratories, New Mexico as well as at Sandia National Laboratories, California. Additionally, results of environmental monitoring efforts at Sandia National Laboratories, New Mexico were reviewed. ALARA is a philosophical approach to radiation protection by managing and controlling radiation exposures (individual and collective) to the work force and to the general public to levels that are As Low As is Reasonably Achievable taking social, technical, economic, practical, and public policy considerations into account. ALARA is not a dose limit but a process which has the objective of attaining doses as far below applicable dose limits As Low As is Reasonably Achievable.

  9. Female bisexuality from adolescence to adulthood: results from a 10-year longitudinal study.

    PubMed

    Diamond, Lisa M

    2008-01-01

    Debates persist over whether bisexuality is a temporary stage of denial or transition, a stable "3rd type" of sexual orientation, or a heightened capacity for sexual fluidity. The present study uses 5 waves of longitudinal data collected from 79 lesbian, bisexual, and "unlabeled" women to evaluate these models. Both the "3rd orientation" and "fluidity" models had support, but the "transitional stage" model did not. Over 10 years, 2/3 of women changed the identity labels they had claimed at the beginning of the study, and 1/3 changed labels 2 or more times. Yet, contrary to the "transitional stage" model, more women adopted bisexual/unlabeled identities than relinquished these identities; few bisexual/unlabeled women ended up identifying as lesbian or heterosexual. Overall, the most commonly adopted identity was "unlabeled." Bisexual/unlabeled women had stable overall distributions of same-sex/other-sex attractions but greater absolute fluctuations in attractions from assessment to assessment than lesbians. All women reported declines in their ratio of same-sex to other-sex behavior over time. These findings demonstrate that the distinction between lesbianism and bisexuality is a matter of degree rather than kind. PMID:18194000

  10. Ablation for atrial fibrillation during mitral valve surgery: 1-year results through continuous subcutaneous monitoring.

    PubMed

    Bogachev-Prokophiev, Alexandr; Zheleznev, Sergey; Romanov, Alexander; Pokushalov, Evgeny; Pivkin, Alexey; Corbucci, Giorgio; Karaskov, Alexander

    2012-07-01

    Continuous monitoring of cardiac rhythm may play an important role in measuring the true symptomatic/asymptomatic atrial fibrillation (AF) burden and improve the management of anti-arrhythmic and anti-thrombotic therapies. Forty-seven patients with mitral valve disease and longstanding persistent AF (LSPAF) underwent a left atrial maze procedure with bipolar radiofrequency and valve surgery. The follow-up data recorded by an implanted loop recorder were analysed after 3, 6 and 12 months. On discharge, 40 (85.1%) patients were in stable sinus rhythm, as documented by in-office electrocardiography (ECG), 4 (8.5%) were in pacemaker rhythm and 3 (6.4%) were in AF. One (2.1%) patient died after 7 months. On 12-month follow-up examination, 30 (65.2%) patients had an AF burden <0.5% and were classified as responders. Three (6.5%) of the 16 non-responders had atrial flutter and 13 (27.7%) had documented AF recurrences with an AF burden >0.5%. Two (4.3%) patients with AF recurrences were completely asymptomatic. Among the symptomatic events stored by the patients, only 27.6% was confirmed as genuine AF recurrences according to the concomitant ECG recorded by the implanted loop recorder. A concomitant bipolar maze procedure during mitral valve surgery is effective in treating AF, as proved by detailed 1-year continuous monitoring. PMID:22514258

  11. Keratin Durability Has Implications for the Fossil Record: Results from a 10 Year Feather Degradation Experiment.

    PubMed

    Moyer, Alison E; Zheng, Wenxia; Schweitzer, Mary H

    2016-01-01

    Keratinous 'soft tissue' structures (i.e. epidermally derived and originally non-biomineralized), include feathers, skin, claws, beaks, and hair. Despite their relatively common occurrence in the fossil record (second only to bone and teeth), few studies have addressed natural degradation processes that must occur in all organic material, including those keratinous structures that are incorporated into the rock record as fossils. Because feathers have high preservation potential and strong phylogenetic signal, in the current study we examine feathers subjected to different burial environments for a duration of ~10 years, using transmission electron microscopy (TEM) and in situ immunofluorescence (IF). We use morphology and persistence of specific immunoreactivity as indicators of preservation at the molecular and microstructural levels. We show that feather keratin is durable, demonstrates structural and microstructural integrity, and retains epitopes suitable for specific antibody recognition in even the harshest conditions. These data support the hypothesis that keratin antibody reactivity can be used to identify the nature and composition of epidermal structures in the rock record, and to address evolutionary questions by distinguishing between alpha- (widely distributed) and beta- (limited to sauropsids) keratin. PMID:27384819

  12. Deaths from volatile substance abuse in those under 18 years: results from a national epidemiological study.

    PubMed Central

    Esmail, A; Meyer, L; Pottier, A; Wright, S

    1993-01-01

    The epidemiology of deaths from volatile substance abuse (VSA) in those under 18 years that occurred in the UK from 1981-90 is described. The analysis of deaths is based on a national register, which has information obtained from a regular survey of coroners, the Office of Population Censuses and Surveys, and a press clippings agency. Altogether 605 people under 18 died from VSA during this period. Seventy per cent of deaths occurred between the ages of 14 and 16. The largest number of deaths were attributed to butane gas lighter refills. There was a large north-south gradient in age specific mortality ratios (Scotland 180, south east England 87) and nearly four times as many deaths occurred in social class V compared with social class I. Deaths from VSA are an important and preventable cause of deaths in those under 18. Strategies aimed at prevention should include measures to reduce experimentation, intervention to reduce socioeconomic deprivation, and health education campaigns aimed at schools and parents. PMID:8215546

  13. 125 years of glacier survey of the Austrian Alpine Club: results and future challenges

    NASA Astrophysics Data System (ADS)

    Fischer, Andrea

    2016-04-01

    One of the aims of the German and Austrian Alpine Club was the scientific investigation of the Alps. In 1891, several years after Swiss initiatives, Richter put out a call to contribute to regular glacier length surveys in the Eastern Alps. Since then more than 100 glaciers have been surveyed on a first biannual and later annual basis. The database includes measured data showing a general glacier retreat since 1891, with two periods of glacier advances in the 1920s and 1980s. Less well known are the sketches and reports which illustrate, for instance, changes in surface texture. The interpretation of length change data requires a larger sample of data for a reasonable interpretation on a regional scale. Nearly every time series in the long history of investigation includes gaps, e.g. in cases of problematic snout positions on steep rock walls or in lakes, or of debris-covered tongues. Current climate change adds the problem of glaciers splitting up into several smaller glaciers which behave differently. Several basic questions need to be addressed to arrive at a most accurate prolongated time series: How should measurements on disintegrating or debris-covered (and thus more or less stagnating) glaciers be documented, and how can we homogenize length change time series? Despite of uncertainties, length change data are amongst the longest available records, bridging the gap to moraine datings of the early holocene.

  14. [The End-of-life Clinic: results from the first year].

    PubMed

    Snijdewind, Marianne C; Onwuteaka-Philipsen, Bregje D; Willems, Dick L

    2016-01-01

    In 2012 the Dutch Dying with Dignity Society (NVVE) founded the End-of-life Clinic, which provides euthanasia or help with assisted suicide at the request of people whose own doctor will not carry out euthanasia if the legal requirements of due care can been fulfilled. As part of an independent evaluation, we looked at the applications received by the End-of-life Clinic during its first year and at the outcomes of these applications. We wrote an extensive article on this subject which was published in JAMA Internal Medicine. One of the most important outcomes is that the End-of-life Clinic rejected a large percentage of the requests for its services, mainly as these came from people with psychiatric conditions. This means that the fears that some people have concerning the alleged End-of-life Clinic policy 'you ask, we comply', appear to be unfounded. On the other hand, the End-of-life Clinic is certainly not the solution for all those people whose requests to their own doctor fall on deaf ears. PMID:26840939

  15. Floating wetland islands as a method of nitrogen mass reduction: results of a 1 year test.

    PubMed

    Vázquez-Burney, Rafael; Bays, James; Messer, Ryan; Harris, Jeffrey

    2015-01-01

    Floating wetland islands (FWIs) were tested in Pasco County, Florida, as a method of reducing total nitrogen (TN) in reclaimed water during reservoir storage. The Pasco County Master Reuse System (PCMRS) is a regional reclaimed-water transmission and distribution system providing wastewater effluent disposal for the county. Total daily mass loading from reclaimed water is limited by nitrogen content in the PCMRS watershed. To test TN reduction efficacy, 20 FWIs were constructed, installed, and monitored in a lined pond receiving PCMRS reclaimed water. In total, 149 m2 of FWIs were installed, distributed as a connected network covering 1,122 m2, or 7% of pond area. Pond hydraulic residence time averaged 15.7 days. Treatment performance was assessed during three consecutive periods: establishment (first 6 months of grow-in), performance (8 months immediately following grow-in), and control (3 months after the FWIs were removed from the pond). The FWIs enhanced pond nitrogen removal capacity by 32%. The primary effect of the FWIs was to decrease organic nitrogen in the pond outflow. By evaluating the difference between the performance and control periods, an incremental TN removal rate for the FWIs was calculated to be 4.2 kg N/m2 FWI per year. PMID:26287828

  16. Keratin Durability Has Implications for the Fossil Record: Results from a 10 Year Feather Degradation Experiment

    PubMed Central

    Moyer, Alison E.; Zheng, Wenxia; Schweitzer, Mary H.

    2016-01-01

    Keratinous ‘soft tissue’ structures (i.e. epidermally derived and originally non-biomineralized), include feathers, skin, claws, beaks, and hair. Despite their relatively common occurrence in the fossil record (second only to bone and teeth), few studies have addressed natural degradation processes that must occur in all organic material, including those keratinous structures that are incorporated into the rock record as fossils. Because feathers have high preservation potential and strong phylogenetic signal, in the current study we examine feathers subjected to different burial environments for a duration of ~10 years, using transmission electron microscopy (TEM) and in situ immunofluorescence (IF). We use morphology and persistence of specific immunoreactivity as indicators of preservation at the molecular and microstructural levels. We show that feather keratin is durable, demonstrates structural and microstructural integrity, and retains epitopes suitable for specific antibody recognition in even the harshest conditions. These data support the hypothesis that keratin antibody reactivity can be used to identify the nature and composition of epidermal structures in the rock record, and to address evolutionary questions by distinguishing between alpha- (widely distributed) and beta- (limited to sauropsids) keratin. PMID:27384819

  17. Results after beta-irradiation (106Ru/106Rh) of choroidal melanomas: 20 years' experience.

    PubMed Central

    Lommatzsch, P K

    1986-01-01

    From 1964 to 1984 309 patients with choroidal melanoma were treated with 106Ru/106Rh beta ray applicators (1000 Gy at the apex of the tumour within 7-14 days). In cases 216 (69.9%) this treatment was successful for a mean follow-up period of 6.7 years after irradiation. In 53 cases (17.2%) the eye had to be enucleated, and 40 patients (12.9%) died from metastases within this period. Of the 216 successfully treated patients 114 (52.8%) developed flat scars and 49 (22.7%) retained a visual acuity of 1.5-0.5. Radiogenic late complications with damage to the retinal capillary system were the main causes of visual deterioration, especially in eyes with tumours close to the posterior pole. The survival rate is substantially higher than that for patients whose eyes were primarily enucleated. beta Ray applicators with 106Ru/106Rh can be recommended as an effective tool and a simple and cheap procedure to cure patients with small and medium sized choroidal melanomas. They save the eye without endangering our patients' lives. Images PMID:3790487

  18. MACHO project 2nd year LMC microlensing results and dark matter implications

    SciTech Connect

    Alcock, C.; Allsman, R.A.; Alves, D.

    1996-02-01

    The MACHO Project is searching for galactic dark matter in the form of massive compact halo objects (Machos). Millions of stars in the Large Magellanic Cloud (LMC), Small Magellanic Cloud (SMC), and Galactic bulge are photometrically monitored in an attempt to detect rare gravitational microlensing events caused by otherwise invisible Machos. Analysis of two years of photometry on 8.5 million stars in the LMC reveals 8 candidate microlensing events, far more than the one event expected from lensing by low-mass stars in known galactic populations. Five these eight events we estimate the optical depth towards the LMC from events with 2 < i < 200 days to be r2 280 about 2.9+1 4/-0.8 X 10-7. This exceeds the optical depth of 0.5 x 10-7 expected for known stars and is to be compared with an optical depth of 4.7 X 10-7 predicted for a `standard` halo composed entirely of Machos. The total mass in this lensing population is 2 +1.2/-0.7 x 10+11 Mo (within 50 kpc from the Galactic center). Event timescales yield a most probable Macho Mass of 0.5 +0.3/-0.2 Mo, although this value is quite model dependent. -0.2

  19. [Development of Human Health Discoveries. 10 years results of Young Innovative Company incubation].

    PubMed

    Marsac, Jean

    2014-01-01

    Medicine is evolving every day in its operating procedures and the services offered to patients, emphasizing personalized medicine, safety and medical benefits. The individual patient is more than ever the hub of healthcare organization. Medical innovation is thus a public health priority. However it requires an accurate assessment of medical utility and risk-benefit ratios, and in-depth analysis of economic and organizational impacts. Ten years of experience in the Paris Biotech Santé company incubator has identified key actions for effective support of research projects and the success of innovative companies. Strong expertise is needed to prepare development plans, ensure compliance with regulatory requirements and obtain research funding. During its first decade, this incubator has created 87 innovative companies employing 1500 people, raised more than 90 million euros of funding, and reached a cumulative company value of 1200 million euros. Key factors of success have been identified, but an analysis of the causes of failure shows that operational adjustments are mandatory, particularly a strong commitment from medical experts, in order to promote access to new and useful products for patients while at the same time assessing their social impact. PMID:26753415

  20. Wave Resource Characteristics Near Humboldt Bay - Results from a 10-year Hindcast

    NASA Astrophysics Data System (ADS)

    Dallman, A.; Neary, V. S.

    2014-12-01

    The Department of Energy's (DOE) marine and hydrokinetic energy (MHK) Program has identified a need to improve modeling capabilities for near-shore wave climate hind-casting, among other applications. The potential wave energy converter (WEC) test or commercial deployment site offshore of Humboldt Bay, CA was selected to investigate the performance of a nearshore SWAN model and the spatial variability of wave statistics. SNL performed a 10-year hindcast using SWAN (Simulating Waves Nearshore), forced by spectral output from a WAVEWATCH III hindcast. The model was found to be insensitive to bottom friction and whitecapping parameterizations for the locations of interest, which included depths of 40m or greater. Predicted significant wave heights were found to be overbiased due to an overbias in the Climate Forecast System Reanalysis (CFSR) winds used to drive WAVEWATCH III. The spatial variability of the wave statistics calculated from the hindcast simulation were found to vary by season and were affected by the wind direction due to geographic features north of Humboldt Bay. Further details of the model performance along with possible areas of improvement will be discussed.

  1. Landfarming of phthalate ester-contaminated soil: Two years of bioremediation results

    SciTech Connect

    Kunze, C.M.; Yu, J.; Wilson, S.; Rezin, J.L.; Andronico, A.

    1995-12-31

    Biorem Technologies Inc. collaborated with Regal Plastics Corporation over 2 years to clean up approximately 600 cubic yards of soil contaminated with di-2-ethylhexyl phthalate ester (DEHP) and No. 2 fuel oil using a landfarming bioremediation process. The contaminated soils consisted of sandy backfill material which had been excavated during the removal of two underground storage tanks (USTs). In 1994, the initial average DEHP concentration was 4,551 ppm while the TPH concentration was 7,252 ppm. In 1995, the initial DEHP concentration was 1067 ppm while TPH was 3,733 ppm. Prior to the implementation of the project, Biorem Technologies completed a laboratory biofeasibility study to demonstrate that a bacterial culture isolated from the site had the capacity to efficiently degrade DEBP in the soil. It was determined during this study that nitrogen and phosphorus nutrient amendments were needed to promote the bioremediation process. In 1994, the soils were loaded on to a lined treatment bed to a depth of 14--16 in. The bed was covered with a greenhouse structure to eliminate stormwater runoff concerns associated with the contaminated soil. To optimize biodegradation, soil moisture and nutrient levels were adjusted. In 1995, a windrow turner replaced the 1994 tilling system. Tarps were used to cover the piles in place of the greenhouse. A leachate collection system was implemented to contain stormwater and leachate.

  2. Robotic Exploration and Science in Pits and Caves: Results from Three Years and Counting of Analog Field Experimentation

    NASA Astrophysics Data System (ADS)

    Wong, U. Y.; Whittaker, W. L.

    2015-10-01

    Robots are poised to access, investigate, and model planetary caves. We present the results of a multi-year campaign to develop robotic technologies for this domain, anchored by the most comprehensive analog field experimentation to date.

  3. Staying on Course: Three-Year Results of the National Guard Youth ChalleNGe Evaluation

    ERIC Educational Resources Information Center

    Millenky, Megan; Bloom, Dan; Muller-Ravett, Sara; Broadus, Joseph

    2011-01-01

    High school dropouts face an uphill battle in a labor market that increasingly rewards skills and postsecondary credentials: they are more likely than their peers to need public assistance, be arrested or incarcerated, and less likely to marry. This report presents results from a rigorous evaluation of the National Guard Youth ChalleNGe Program,…

  4. Eight Years of Specialist Training of Dutch Intellectual Disability Physicians: Results of Scientific Research Education

    ERIC Educational Resources Information Center

    Evenhuis, Heleen M.; Penning, Corine

    2009-01-01

    Training in scientific research methods and skills is a vital part of Dutch specialist training in intellectual disability medicine. The authors evaluated results of such training at one Dutch university medical facility that had an obligatory research program involving projects conducted by the physicians-in-training (topics, teamwork, acquired…

  5. WHAT’S CAUSING TOXICITY IN SEDIMENTS? RESULTS OF 20 YEARS OF TOXICITY IDENTIFICATION AND EVALUATIONS

    EPA Science Inventory

    Sediment toxicity identification and evaluation (TIE) methods have been used for 20 yr to identify the causes of toxicity in sediments around the world. In the present study, the authors summarize and categorize results of 36 peer-reviewed TIE studies (67 sediments) into nonioni...

  6. A 10-Year Mechatronics Curriculum Development Initiative: Relevance, Content, and Results--Part I

    ERIC Educational Resources Information Center

    Das, S.; Yost, S. A.; Krishnan, M.

    2010-01-01

    This paper describes the first phase of a Mechatronics Curriculum Development effort--the design of an "Introduction to Mechatronics" course, the infusion of mechatronics activities throughout the curriculum and in outreach activities, and assessment results. In addition, the relevance and impact of such a curriculum on the education of engineers…

  7. New Mexico Enhanced ACT and SAT Results. School Year 1992-1993.

    ERIC Educational Resources Information Center

    Cavatta, M. Louise

    Students in New Mexico may take either the American College Test Assessment (ACT) or the Scholastic Aptitude Test (SAT), although the ACT is most often used in New Mexico. Results from both examinations are presented in this report, based on those students who were expected to graduate in 1993 and who had expressed an interest in attending…

  8. Hedging and severity of pecan scab – a second year of results

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Pecan scab, caused by the plant pathogenic fungus Fusicladium effusum, is the major disease of pecan in Georgia and elsewhere in the region. There are several reasons for hedging, and some issues may arise as a result of the hedging management practice. One of those issues might be increased disease...

  9. Final-Year Results from the i3 Scale-Up of Reading Recovery

    ERIC Educational Resources Information Center

    May, Henry; Sirinides, Philip; Gray, Abby; Davila, Heather Goldsworthy; Sam, Cecile; Blalock, Toscha; Blackman, Horatio; Anderson-Clark, Helen; Schiera, Andrew J.

    2015-01-01

    As part of the 2010 economic stimulus, a $55 million "Investing in Innovation" (i3) grant from the US Department of Education was awarded to scale up Reading Recovery across the nation. This paper presents the final round of results from the large-scale, mixed methods randomized evaluation of the implementation and impacts of Reading…

  10. Sixty years of interest in flow and transport theories: Sources of inspiration and a few results

    NASA Astrophysics Data System (ADS)

    Raats, Peter A. C.

    2016-04-01

    By choosing to major in soil physics at Wageningen now exactly 60 years ago, I could combine my interest in exact sciences with my experience of growing up on a farm. I never regretted that choice. In the first twenty years, I profited much from close contacts with members of the immediate post-WW II generation of soil physicists (especially Jerry Bolt, Arnold Klute, Ed Miller, Champ Tanner, Wilford Gardner, John Philip, and Jan van Schilfgaarde), chemical engineers (especially at UW Madison the trio Bob Bird, Warren Stewart and Ed Lightfoot) and experts in continuum mechanics (especially at Johns Hopkins Clifford Truesdell and Jerald Ericksen). As graduate student at Illinois with Klute, to describe flow and transport theories in soil science I initially explored as possible framework thermodynamics of irreversible processes (TIP), but soon switched to the continuum theory of mixtures (CTM), initiated by Truesdell in 1957. In CTM, the balance of forces gave a rational basis for flux equations. CTM allowed me to deal with swelling/shrinkage, role of inertia, boundary conditions, and structured soils. Later, I did use TIP to deal with certain aspects of transfer of water and heat in soils and selective uptake of water and nutrients by plant roots. Recently, a variety of theories for upscaling from the pore scale to the Darcy scale have clarified the potential, limits and common ground of CTM and TIP. A great advantage of CTM is that it provides geometric tools suited for kinematic aspects of flow, transport, and growth/decay processes. In particular, the concept of material coordinates of the solid phase that I used in my PhD thesis to cope with large deformation due to swelling/shrinkage of soils, later also turned to be useful to deal with simultaneous shrinkage and decay in peat soils and compost heaps, and the growth of plant tissues. Also, by focusing on the material coordinates for the water, it became possible to describe transport of solutes in unsaturated

  11. Everolimus and early calcineurin inhibitor withdrawal: 3-year results from a randomized trial in liver transplantation.

    PubMed

    Sterneck, M; Kaiser, G M; Heyne, N; Richter, N; Rauchfuss, F; Pascher, A; Schemmer, P; Fischer, L; Klein, C G; Nadalin, S; Lehner, F; Settmacher, U; Neuhaus, P; Gotthardt, D; Loss, M; Ladenburger, S; Paulus, E M; Mertens, M; Schlitt, H J

    2014-03-01

    The feasibility of de novo everolimus without calcineurin inhibitor (CNI) therapy following liver transplantation was assessed in a multicenter, prospective, open-label trial. Liver transplant patients were randomized at 4 weeks to start everolimus and discontinue CNI, or continue their current CNI-based regimen. The primary endpoint was adjusted estimated GFR (eGFR; Cockcroft-Gault) at month 11 post randomization. A 24-month extension phase followed 81/114 (71.1%) of eligible patients to month 35 post randomization. The adjusted mean eGFR benefit from randomization to month 35 was 10.1 mL/min (95% confidence interval [CI] -1.3, 21.5 mL/min, p = 0.082) in favor of CNI-free versus CNI using Cockcroft-Gault, 9.4 mL/min/1.73 m(2) (95% CI -0.4, 18.9, p = 0.053) with Modification of Diet in Renal Disease (four-variable) and 9.5 mL/min/1.73 m(2) (95% CI -1.1, 17.9, p = 0.028) using Nankivell. The difference in favor of the CNI-free regimen increased gradually over time due to a small progressive decline in eGFR in the CNI cohort despite a reduction in CNI exposure. Biopsy-proven acute rejection, graft loss and death were similar between groups. Adverse events led to study drug discontinuation in five CNI-free patients and five CNI patients (12.2% vs. 12.5%, p = 1.000) during the extension phase. Everolimus-based CNI-free immunosuppression is feasible following liver transplantation and patients benefit from sustained preservation of renal function versus patients on CNI for at least 3 years. PMID:24502384

  12. One Year Clinical Outcomes of Renal Artery Stenting: The Results of ODORI Registry

    SciTech Connect

    Sapoval, M.; Tamari, I.; Goffette, P.; Downes, M.; Senechal, Q.; Fanelli, F.; Reimer, P.; Negaiwi, Z.; Cassin, P. De; Heye, S.; Korobov, V.; Tsetis, D.; Abada, H.

    2010-06-15

    The safety, efficacy and long term clinical benefits of renal artery revascularization by stenting are still a matter of debate. The aim of our study was to define the safety and efficacy of renal artery stenting with the Tsunami peripheral stent (Terumo Corporation, Tokyo, Japan). The ODORI was a prospective, multicentre registry which enrolled 251 consecutive patients, (276 renal arteries) in 36 centres across Europe. The primary endpoint was acute procedural success defined as <30% residual stenosis after stent placement. Secondary endpoints included major adverse events, blood pressure control, serum creatinine level, and target lesion revascularization (TLR) at 6 and 12 months. Patients were 70 {+-} 10 years old, 59% were male, 33% had diabetes, and 96% hypertension. The main indications for renal stent implantation were hypertension in 83% and renal salvage in 39%. Direct stent implantation was performed in 76% of the cases. Acute success rate was 100% with residual stenosis of 2.5 {+-} 5.4%. Systolic/diastolic blood pressure decreased from a mean of 171/89 at baseline to 142/78 mmHg at 6 months (p < 0.0001 vs. baseline), and 141/80 mmHg at 12 months (p < 0.0001 vs. baseline). Mean serum creatinine concentration did not change significantly in the total population. However, there was significant improvement in the highest tercile (from 283 {mu}mol/l at baseline to 205 and 209 {mu}mol/l at 6 and 12 months respectively). At 12-months, rates of restenosis and TLR were 6.6 and 0.8% respectively. The 12 month cumulative rate of all major clinical adverse events was 6.4% while the rate of device or procedure related events was 2.4%. In hypertensive patients with atherosclerotic renal artery stenosis Tsunami peripheral balloon-expandable stent provides a safe revascularization strategy, with a potential beneficial impact on hypertension control and renal function in the highest risk patients.

  13. Variability of Ionosphere over Africa: Results from International Heliophysical Year IHY

    NASA Astrophysics Data System (ADS)

    Rabiu, Babatunde

    Space Environment Research Centre of Kyushu University, Japan, installed 13 units of Magnetic Data Acquisition Systems MAGDAS over Africa during the International Heliophysical Year IHY. Institute for Scientific Research Bolton College USA in collaboration with the Aeronomy and Radiopropagation Laboratory of International Centre for Theoretical Physics, Italy, has jointly placed over 15 units of GPS systems over Africa suitable for total electron content TEC and ionospheric scintillation studies. Magnetic records from 10 stations along the African 96o Magnetic Meridian (Geographical 30o -40o East) were examined for Solar quiet daily Sq variation due in the three geomagnetic field components H, D and Z. Latitudinal variations of Sq in the geomagnetic components were examined. Signatures of equatorial electrojet and worldwide Sq were identified and studied in detail. H field experienced more variation within the equatorial electrojet zone. Diurnal and seasonal variations of the geomagnetic variations in the three components were discussed. Levels of inter-relationships between the Sq and its variability in the three components were statistically derived and interpreted in line with the mechanisms responsible for the variations of the geomagnetic field. Data from 2 magnetic observatories within equatorial electrojet EEJ strip and 2 stations outside the EEJ strip were employed to evaluate and study the signatures of the Equatorial electrojet over the African sector. The transient variations of the EEJ at two almost parallel axes using Lagos-Ilorin and Nairobi-Addis pairs were examined. The EEJ appear stronger in East than West Africa. The magnitudes and patterns of variation of EEJ strength along the two axes were examined for any simultaneity or otherwise of responses to ionospheric processes. The flow gradient of EEJ along the African sector was estimated and its diurnal variation studied. Complementarily data from GPS was used to study diurnal and seasonal

  14. Observables sensitive to absolute neutrino masses: A reappraisal after WMAP 3-year and first MINOS results

    SciTech Connect

    Fogli, G. L.; Lisi, E.; Marrone, A.; Melchiorri, A.; Serra, P.; Palazzo, A.; Silk, J.; Slosar, A.

    2007-03-01

    In the light of recent neutrino oscillation and nonoscillation data, we revisit the phenomenological constraints applicable to three observables sensitive to absolute neutrino masses: The effective neutrino mass in single beta decay (m{sub {beta}}); the effective Majorana neutrino mass in neutrinoless double beta decay (m{sub {beta}}{sub {beta}}); and the sum of neutrino masses in cosmology ({sigma}). In particular, we include the constraints coming from the first Main Injector Neutrino Oscillation Search (MINOS) data and from the Wilkinson Microwave Anisotropy Probe (WMAP) three-year (3y) data, as well as other relevant cosmological data and priors. We find that the largest neutrino squared mass difference is determined with a 15% accuracy (at 2{sigma}) after adding MINOS to world data. We also find upper bounds on the sum of neutrino masses {sigma} ranging from {approx}2 eV (WMAP-3y data only) to {approx}0.2 eV (all cosmological data) at 2{sigma}, in agreement with previous studies. In addition, we discuss the connection of such bounds with those placed on the matter power spectrum normalization parameter {sigma}{sub 8}. We show how the partial degeneracy between {sigma} and {sigma}{sub 8} in WMAP-3y data is broken by adding further cosmological data, and how the overall preference of such data for relatively high values of {sigma}{sub 8} pushes the upper bound of {sigma} in the sub-eV range. Finally, for various combination of data sets, we revisit the (in)compatibility between current {sigma} and m{sub {beta}}{sub {beta}} constraints (and claims), and derive quantitative predictions for future single and double beta decay experiments.

  15. Magnetospheric Line Radiation: Survey results using 6.5 years of DEMETER spacecraft data

    NASA Astrophysics Data System (ADS)

    Bezdekova, Barbora; Nemec, Frantisek; Parrot, Michel; Santolik, Ondrej; Kruparova, Oksana

    2015-04-01

    Frequency-time spectrograms of electromagnetic emissions observed in the Earth's inner magnetosphere at frequencies between about 1 and 8 kHz sometimes consist of several nearly horizontal and almost equidistant intense lines. The emissions of this type were observed both by ground-based instruments and by satellites, and they are usually called Magnetospheric Line Radiation (MLR). We compiled a list of all MLR events observed by the low-altitude DEMETER spacecraft during the duration of the mission (2004-2010). Altogether, 1230 MLR events were identified, which likely represents the largest database available to date. We analyze a possible connection between the MLR occurrence and solar wind parameters using the superposed epoch analysis. We show that the MLR occurrence is enhanced during specific solar wind parameters, being larger in relation to the interplanetary shocks. We further show that there is a connection between the MLR occurrence and the season of the year, with the events being more frequent during the northern winter than during the northern summer. As for the spatial distribution of the event occurrence, the events are less frequent at geomagnetic longitudes of the South Atlantic Anomaly. We also analyze the energy spectra of electrons precipitating at the times of MLR events, and we derive energy-latitude plot of electron flux enhancements related to the MLR occurrence. Finally, we perform a detailed wave analysis of two MLR events for which high resolution multicomponent data are available. It is found that the events are right-handed nearly circularly polarized, propagating at oblique wave normal angles from larger radial distances and lower geomagnetic latitudes.

  16. Yucca mountain project getter program results(year 1):I-129 and other anions of concern.

    SciTech Connect

    Krumhansl, James Lee; Pless, Jason; Chwirka, J. Benjamin

    2006-07-01

    Although high level nuclear wastes (HLW) contain a daunting array of radioisotopes, only a restricted number are long-lived enough to be problematic, and of these many are either effectively insoluble or are likely to be scavenged from solution by minerals indigenous to all aquifers. Those few constituents likely to travel significant distances through aquifers either form colloids (and travel as particulates) or anions--which are not sorbed onto the predominantly negatively charged mineral surfaces. Iodine ({sup 129}I) is one such constituent and may travel as either iodide (I{sup -}) or iodate (IO{sub 3}{sup -}) depending on whether conditions are mildly reducing or oxidizing. Conventionally, {sup 99}Tc (traveling as TcO{sub 4}{sup -}) is regarded as being of greater concern since it is both more abundant and has a shorter half life (e.g., has a higher specific activity). However, it is unclear whether TcO{sub 4}{sup -} will ever actually form in the mildly reducing environments thought likely within degrading HLW canisters. Instead, technetium may remain reduced as highly insoluble Tc(IV), in which case {sup 129}I might become a significant risk driver in performance assessment (PA) calculations. In the 2004-2005 time frame the US Department of Energy (DOE)--Office of Civilian Radioactive Waste Management (OCRUM), Office of Science and Technology International (S&T) funded a program to identify ''getters'' for possible placement in the invert beneath HLW packages in the repository being planned by the Yucca Mountain Project (YMP). This document reports on progress made during the first (and only) year of this activity. The problem is not a new one and the project did not proceed in a complete vacuum of information. Potential leads came from past studies directed at developing anion getters for a near surface low-level waste facility at Hanford, which suggested that both copper-containing compounds and hydrotalcite-group minerals might be promising. Later work

  17. Monteggia-like lesions – treatment strategies and one-year results

    PubMed Central

    Laun, Reinhold; Wild, Michael; Brosius, Lars; Hakimi, Mohssen

    2015-01-01

    Introduction: The eponym “Monteggia fracture” includes various patterns of complex fracture-dislocations of the proximal ulna and radius, which are not well defined yet. They are frequently described as Monteggia-like lesions or Monteggia equivalent injuries. Until today, these injury patterns have been reported rarely. The objective of this retrospective study was to better define patterns of injury and to document the short-term results of treatment with current fixation techniques. Methods: Ten patients with a Monteggia-like lesion were included in this study and clinical and radiological follow-up examinations at an average of 12.3 months after the trauma were performed. For clinical follow-up the Mayo Modified Wrist Score, the Mayo Elbow Performance Score, the functional rating index of Broberg and Morrey, and the DASH score were utilized. Results: Osteosynthesis of the ulna was performed using a proximally contoured or precontoured LCP (locking compression plate) in all patients. All patients had a fracture of the radial head. All patients with a Mason type III radial head fracture received a cemented bipolar radial head prosthesis. All Mason type II fractures were treated with open reduction and internal fixation using mini screws. In all Mason type I fractures the treatment of the radial head dislocation was by closed reduction. Associated coronoid fractures were stabilized with lag screws through the ulnar plate or with independent lag screws after reduction of the fracture. According to the aforementioned scoring systems good to excellent results could be achieved. Conclusions: Our findings demonstrate that good or excellent short-term results can be obtained if the injury is classified correctly and a standardized surgical treatment of all components of the injury is achieved. Further studies with larger patient populations and longer follow up periods are needed to evaluate long-term effectiveness of this treatment concept. PMID:26734535

  18. How to Interpret Thyroid Biopsy Results: A Three-Year Retrospective Interventional Radiology Experience

    SciTech Connect

    Oppenheimer, Jason D. Kasuganti, Deepa; Nayar, Ritu; Chrisman, Howard B.; Lewandowski, Robert J.; Nemcek, Albert A.; Ryu, Robert K.

    2010-08-15

    Results of thyroid biopsy determine whether thyroid nodule resection is appropriate and the extent of thyroid surgery. At our institution we use 20/22-gauge core biopsy (CBx) in conjunction with fine-needle aspiration (FNA) to decrease the number of passes and improve adequacy. Occasionally, both ultrasound (US)-guided FNA and CBx yield unsatisfactory specimens. To justify clinical recommendations for these unsatisfactory thyroid biopsies, we compare rates of malignancy at surgical resection for unsatisfactory biopsy results against definitive biopsy results. We retrospectively reviewed a database of 1979 patients who had a total of 2677 FNA and 663 CBx performed by experienced interventional radiologists under US guidance from 2003 to 2006 at a tertiary-care academic center. In 451 patients who had surgery following biopsy, Fisher's exact test was used to compare surgical malignancy rates between unsatisfactory and malignant biopsy cohorts as well as between unsatisfactory and benign biopsy cohorts. We defined statistical significance at P = 0.05. We reported an overall unsatisfactory thyroid biopsy rate of 3.7% (100/2677). A statistically significant higher rate of surgically proven malignancies was found in malignant biopsy patients compared to unsatisfactory biopsy patients (P = 0.0001). The incidence of surgically proven malignancy in unsatisfactory biopsy patients was not significantly different from that in benign biopsy patients (P = 0.8625). In conclusion, an extremely low incidence of malignancy was associated with both benign and unsatisfactory thyroid biopsy results. The difference in incidence between these two groups was not statistically significant. Therefore, patients with unsatisfactory biopsy specimens can be reassured and counseled accordingly.

  19. A new 10,000 year pollen record from Lake Kinneret (Israel) - first results

    NASA Astrophysics Data System (ADS)

    Schiebel, V.; Litt, T.; Nowaczyk, N.; Stein, M.; Wennrich, V.

    2012-04-01

    Lake Kinneret - as part of the Jordan Rift Valley in Israel - is situated in the southern Levant, which is affected by Eastern Mediterranean climate. The present lake level is around 212 m below msl. Lake Kinneret has a surface of ca. 165 km2 and its watershed comprises the Galilee, the Golan Heights, the Hermon Range and the Anti-Lebanon Mountains. Its most important tributary is the Jordan River. The geography of the Lake Kinneret region is characterised by big differences in altitude. Steep slopes rise up to 560 m above the lake level in the west, north, and east. Mount Hermon (2814 m above mean sea level, amsl) is the highest summit of the Anti-Lebanon Range, and Mount Meron (1208 m amsl) located in the Upper Galilee encircle Lake Kinneret within a 100-km range in the northwest. Due to the pattern of average precipitation, distinct plant-geographical territories converge in the region: The Mediterranean and the Irano-Turanian biom (after Zohary). Varying ratios of characteristic pollen taxa representing certain plant associations serve as proxy data for the reconstruction of paleovegetation, paleoenvironment, and paleoclimate. We present a pollen record based on analyses of sediment cores obtained during a drilling campaign on Lake Kinneret in March 2010. A composite profile of 17.8 m length was established by correlating two parallel cores by using magnetic susceptibility data. Our record encompasses the past ca. 10,000 years of a region, which has been discussed as migration corridor of humans to Europe and, being part of the Fertile Crescent, as the cradle of agriculture in West Asia. Conclusions concerning human impact on vegetation and therefore population density can be drawn by analysing changes of ratios of certain plant taxa such as Olea europaea cultivated in this region since the Chalcolithic Period (6,500 BP). In addition, stable isotope data were produced from discrete bulk samples, and the elemental composition of the sediments was determined by

  20. Long-term results of viscocanalostomy and phacoviscocanalostomy: a twelve-year follow-up study

    PubMed Central

    Gunenc, Uzeyir; Ozturk, Taylan; Arikan, Gul; Kocak, Nilufer

    2015-01-01

    AIM To evaluate the long-term efficacy and safety results of viscocanalostomy and phacoviscocanalostomy. METHODS The charts of 49 glaucoma patients who underwent viscocanalostomy or phacoviscocanalostomy surgery between February 1999 and August 2004 were reviewed retrospectively. Thirty-one eyes of 21 glaucoma patients who underwent filtering procedure with a postoperative follow-up of at least 5y were included in the study. Results of complete ophthalmologic examinations were recorded and statistically analyzed. Long-term surgical outcome was defined as an overall success when intraocular pressure (IOP) was found as ≤20 mm Hg with or without antiglaucomatous medication at the last follow-up visit, while it was defined as a complete success when IOP was measured ≤20 mm Hg without antiglaucomatous medication. RESULTS Mean age was 68.1±9.6y (range: 32-81y). Mean follow-up time was 101.5±27.3mo (range: 60-144mo). Viscocanalostomy was performed in 8 eyes (25.8%) and phacoviscocanalostomy was performed in 23 eyes (74.2%). The mean preoperative IOP was 23.1±7.6 mm Hg with 2.1±1.0 medications, while mean IOP was 16.8±3.8 mm Hg with 0.9±1.1 medication at the last follow-up visit. Both the IOP decrease and the reduction in the antiglaucomatous medication were statistically significant (P<0.001 and P<0.001). No case required further glaucoma surgery. Overall success and complete success were found as 87.1% and 51.6%, respectively. Complete success rate was statistically higher in phacoviscocanalostomy group compared with the viscocanalostomy group (P=0.031), however there was no significant difference in overall success rate between two groups (P=0.072). CONCLUSION Both viscocanalostomy and phacoviscocanalostomy provide good IOP reduction in the long-term period. PMID:26682166

  1. Analysis of 10-Year Training Results of Medical Students Using the Microvascular Research Center Training Program.

    PubMed

    Onoda, Satoshi; Kimata, Yoshihiro; Sugiyama, Narushi; Tokuyama, Eijiro; Matsumoto, Kumiko; Ota, Tomoyuki; Thuzar, Moe

    2016-06-01

    Background In this article, we reviewed the training results of medical students using the Microvascular Research Center Training Program (MRCP), and proposed an ideal microsurgical training program for all individuals by analyzing the training results of medical students who did not have any surgical experience. Methods As of 2015, a total of 29 medical students completed the MRCP. In the most recent 12 medical students, the number of trials performed for each training stage and the number of rats needed to complete the training were recorded. Additionally, we measured the operating time upon finishing stage 5 for the recent six medical students after it became a current program. Results The average operating time upon finishing stage 5 for the recent six medical students was 120 minutes ± 11 minutes (standard deviation [SD]). The average vascular anastomosis time (for the artery and vein) was 52 minutes ± 2 minutes (SD). For the most recent 12 medical students, there was a negative correlation between the number of trials performed in the non-rat stages (stages 1-3) and the number of rats used in the rat stages (stages 4-5). Conclusion Analysis of the training results of medical students suggests that performing microsurgery first on silicon tubes and chicken wings saves animals' lives later during the training program. We believe that any person can learn the technique of microsurgery by performing 7 to 8 hours of training per day over a period of 15 days within this program setting. PMID:26636888

  2. [Functional and radiographic results in partial unipolar hip joint arthroplasty after 6-15 years].

    PubMed

    Todorović, A; Tulić, G; Vucetić, C; Bumbasirević, M; Dulić, B; Blagojević, Z; Kadija, M

    2006-01-01

    Due to extreme conditions during civil war in early 1990's we were forced to deviate from accepted guidelines in treatment of intracapsular fractures of the femoral neck. Therefore, majority of patients were treated non-operatively. In those that were subjected to surgery, unipolar hemiarthroplasty was treatment of choice, since conditions permitted us to attempt osteofixation in very few, youngest of our patients. As a result of this practice born of necessity, we can now look back and learn from this unique experience. PMID:17688044

  3. Inspection of Nickel Alloy Welds: Results from Five Year International Program

    SciTech Connect

    Prokofiev, Iouri; Cumblidge, Stephen E.; Doctor, Steven R.

    2011-06-23

    The U.S. Nuclear Regulatory Commission established and coordinated the international Program for the Inspection of Nickel alloy Components (PINC). The goal of PINC was to evaluate the capabilities of various nondestructive examination (NDE) techniques to detect and characterize primary water stress corrosion cracking (PWSCC) in dissimilar metal welds. Round-robin results showed that a combination of conventional and phased-array ultrasound provide the highest performance for flaw detection and depth sizing in dissimilar metal piping welds. The effective detection of flaws in bottom-mounted instrumentation penetrations by eddy current and ultrasound shows that it may be possible to reliably inspect these components in the field.

  4. The Dome C Gattini sky brightness cameras: results from the first year of operation

    NASA Astrophysics Data System (ADS)

    Moore, A. M.; Leslie, T.; Ashley, M. C. B.; Aristidi, E.; Bedding, T.; Briguglio, R.; Busso, M.; Candidi, M.; Cutispoto, G.; Distefano, E.; Everett, J.; Kenyon, S.; Lawrence, J.; Le Roux, B.; Luong-van, D.; Phillips, A.; Ragazzoni, R.; Sabbatini, L.; Salinari, P.; Stello, D.; Storey, J. W. V.; Taylor, M.; Tosti, G.; Travouillon, T.

    The Gattini-DomeC project, part of the IRAIT site testing campaign and ongoing since January 2006, consists of two cameras for the measurement of optical sky brightness, large area cloud cover, and auroral detection above the DomeC site, home of the French-Italian Concordia station. The cameras are transit in nature and are virtually identical except for the nature of the lenses. The cameras have operated throughout the past two Antarctic winter seasons and here we present the results obtained from the 2006 winter-time dataset of the wide field “All-sky camera".

  5. Communicating HIV Results to Low-Risk Individuals: Still Hazy After All These Years.

    PubMed

    Ellis, Katrina M; Brase, Gary L

    2015-01-01

    Revised Centers for Disease Control and Prevention recommendations on HIV testing now promote testing of most risk groups. However, positive results for low-risk individuals are more likely to be false positives than for high-risk individuals, making clear communication of test results even more imperative. In a study, we evaluated current counseling of low-risk test recipients via a sample of 29 HIV hotline counselors from U.S. state and national hotlines. 100% of counselors interviewed failed to provide an accurate conditional HIV risk for low-risk women, but were more likely than a 1998 German sample to report that false positives could occur. In a second study, undergraduates read idealized transcripts of interviews with HIV counselors and computed conditional risk for a low-risk individual. The natural frequency format offered a small but significant improvement in conditional reasoning, comparable to the effect of numerical literacy. Applications for ecologically valid numerical presentations of risk and implications for numeracy are discussed. PMID:26149160

  6. A knotless, one-haptic fixation of posterior chamber intraocular lenses: one-year results

    PubMed Central

    Kongsap, Pipat

    2015-01-01

    AIM To assess the results of a modified technique for scleral fixation of a posterior chamber intraocular lens (IOL) in eyes which had deficient of posterior capsular support. METHODS This retrospective study was comprised of ten patients with deficient posterior capsular support who underwent one-haptic fixation of posterior chamber IOLs, between February 2010 and October 2011. IOL as implanted with one haptic supported on the capsular remnant and the other haptic drawn into the sulcus by anchoring suture without a knot. All patients were evaluated for pre- and postoperative visual acuity, lens centration, intra-and postoperative complications. RESULTS A knotless, one-haptic fixation of posterior chamber IOLs has successfully been performed on ten eyes. All cases had inadequate capsular support (i.e. a capsular tear ranged from 5 to 7 clock hours). The average age was 74.25±8.87y (SD). The average postoperative uncorrected visual acuity was 0.51 logMAR. Complications included hyphema in one eye, a mild inflammatory reaction in the anterior chamber in two eyes, and a transient rise in IOP in one eye. Neither IOL tilt nor dislocation was observed and there were no later complications. CONCLUSION In the presence of insufficient capsular support, a knotless, one-haptic fixation of posterior chamber IOLs is a safe and viable option which reduces the operation time, and minimizes postoperative suture-related complications. PMID:25709917

  7. First Year Wilkinson Microwave Anisotropy Probe (WMAP)Observations: Preliminary Maps and Basic Results

    NASA Technical Reports Server (NTRS)

    Bennett, C. L.; Halpern, M.; Hinshaw, G.; Jarosik, N.; Kogut, A.; Limon, M.; Meyer, S. S.; Page, L.; Spergel, D. N.; Tucker, G. S.

    2003-01-01

    We present full sky microwave maps in five frequency bands (23 to 94 GHz) from the WMAP first year sky survey. Calibration errors are less than 0.5% and the low systematic error level is well specified. The cosmic microwave background (CMB) is separated from the foregrounds using multifrequency data. The sky maps are consistent with the 7 in. full-width at half-maximum (FWHM) Cosmic Background Explorer (COBE) maps. We report more precise, but consistent, dipole and quadrupole values. The CMB anisotropy obeys Gaussian statistics with -58 less than f(sub NL) less than 134 (95% CL). The 2 less than or = l less than or = 900 anisotropy power spectrum is cosmic variance limited for l less than 354 with a signal-to-noise ratio greater than 1 per mode to l = 658. The temperature-polarization cross-power spectrum reveals both acoustic features and a large angle correlation from reionization. The optical depth of reionization is tau = 0.17 +/- 0.04, which implies a reionization epoch of t(sub r) = 180(sup +220, sub -80) Myr (95% CL) after the Big Bang at a redshift of z(sub r) = 20(sup +10, sub -9) (95% CL) for a range of ionization scenarios. This early reionization is incompatible with the presence of a significant warm dark matter density. A best-fit cosmological model to the CMB and other measures of large scale structure works remarkably well with only a few parameters. The age of the best-fit universe is t(sub 0) = 13.7 +/- 0.2 Gyr old. Decoupling was t(sub dec) = 379(sup +8, sub -7)kyr after the Big Bang at a redshift of z(sub dec) = 1089 +/- 1. The thickness of the decoupling surface was Delta(sub z(sub dec)) = 195 +/- 2. The matter density of the universe is Omega(sub m)h(sup 2) = 0.135(sup +0.008, sub -0.009) the baryon density is Omega(sub b)h(sup 2) = 0.0224 +/- 0.0009, and the total mass-energy of the universe is Omega(sub tot) = 1.02 +/- 0.02. There is progressively less fluctuation power on smaller scales, from WMAP to fine scale CMB measurements to galaxies

  8. Building the European Seismological Research Infrastructure: results from 4 years NERIES EC project

    NASA Astrophysics Data System (ADS)

    van Eck, T.; Giardini, D.

    2010-12-01

    The EC Research Infrastructure (RI) project, Network of Research Infrastructures for European Seismology (NERIES), implemented a comprehensive European integrated RI for earthquake seismological data that is scalable and sustainable. NERIES opened a significant amount of additional seismological data, integrated different distributed data archives, implemented and produced advanced analysis tools and advanced software packages and tools. A single seismic data portal provides a single access point and overview for European seismological data available for the earth science research community. Additional data access tools and sites have been implemented to meet user and robustness requirements, notably those at the EMSC and ORFEUS. The datasets compiled in NERIES and available through the portal include among others: - The expanded Virtual European Broadband Seismic Network (VEBSN) with real-time access to more then 500 stations from > 53 observatories. This data is continuously monitored, quality controlled and archived in the European Integrated Distributed waveform Archive (EIDA). - A unique integration of acceleration datasets from seven networks in seven European or associated countries centrally accessible in a homogeneous format, thus forming the core comprehensive European acceleration database. Standardized parameter analysis and actual software are included in the database. - A Distributed Archive of Historical Earthquake Data (AHEAD) for research purposes, containing among others a comprehensive European Macroseismic Database and Earthquake Catalogue (1000 - 1963, M ≥5.8), including analysis tools. - Data from 3 one year OBS deployments at three sites, Atlantic, Ionian and Ligurian Sea within the general SEED format, thus creating the core integrated data base for ocean, sea and land based seismological observatories. Tools to facilitate analysis and data mining of the RI datasets are: - A comprehensive set of European seismological velocity reference

  9. Ten to twelve-year results with the Zweymüller cementless total hip prosthesis.

    PubMed

    Vervest, Ton M J S; Anderson, Patricia G; Van Hout, Freek; Wapstra, Frits-Hein; Louwerse, Robert T; Koetsier, Juriaan W A

    2005-04-01

    Between January 1987 and December 1990, 221 Zweymüller cementless total hip arthroplasties were performed in 211 patients with idiopathic osteoarthritis. A total of 136 patients (142 prostheses) were evaluated at a mean follow-up of 134 months (SD 9.5). The study group consisted of 78 Hochgezogen and 64 Stepless stem prostheses, all with a threaded titanium cup and ceramic head. No clinical and radiological differences were found between the 2 stem prostheses. Seven cups had been revised because of aseptic loosening; 17 cups showed radiolucent lines, osteolysis, or migration. Mean linear polyethylene wear of 105 (74%) cups was 0.46 mm (SD 0.27), with an annual wear of 0.04 mm (SD 0.02). Wear did not correlate with pain, cup migration, radiolucent lines, or osteolysis. Cumulative survival was 96%. Zweymüller cementless total hip arthroplasty showed good midterm results. PMID:15809956

  10. Five-year ALARA review of dosimetry results : 1 January 2008 through 31 December 2012.

    SciTech Connect

    Paulus, Luke R.

    2013-08-01

    A review of personnel dosimetry (external and internal) and environmental monitoring results from 1 January 2008 through 31 December 2012 performed at Sandia National Laboratories, New Mexico was conducted to demonstrate that radiation protection methods used are compliant with regulatory limits and conform with the ALARA philosophy. ALARA is the philosophical approach to radiation protection by managing and controlling radiation exposures (individual and collective) to the work force and to the general public to levels that are As Low As is Reasonably Achievable taking social, technical, economic, practical, and public policy considerations into account. ALARA is not a dose limit but a process which has the objective of attaining doses as far below applicable dose limits As Low As is Reasonably Achievable.

  11. Results of calendar year 1995 Well Inspection and Maintenance Program Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect

    McMaster, B.W.

    1996-07-01

    This document is a compendium of results of the 1995 Monitor Well Inspection and Maintenance Program at the US Department of Energy`s Oak Ridge Y-12 Plant. This report documents the work relating to well inspections and maintenance requests. Inspections are implemented in order to better assess the condition and maintenance needs of wells that are actively being monitored. Currently this approach calls for inspecting all wells on a routine (annual or triennial) basis which are: (1) in an active sampling program; (2) included in a hydrologic study; or (3) not in service, but not scheduled for plugging and abandonment. Routine inspections help to ensure that representative groundwater samples and hydrologic data are being collected, and contribute to the effective longevity of each well. This report formally presents well inspection and maintenance activities that were conducted at the Y-12 Plant from August through December 1995.

  12. Ten Years of Results of Modified Frontalis Muscle Transfer for the Correction of Blepharoptosis

    PubMed Central

    Kim, Woo Jeong; Park, Dae Hwan

    2016-01-01

    Background Conventional frontalis transfer may cause a range of complications. In order to overcome complications, we made modifications to the surgical technique, and compared the outcomes of patients who underwent conventional frontalis transfer with those of patients who underwent modified frontalis transfer. Methods We conducted a retrospective study of 48 patients (78 eyes) who underwent conventional frontalis transfer between 1991 and 2003 (group A) and 67 patients (107 eyes) who underwent modified frontalis transfer between 2004 and 2014 (group B). The frontalis transfer procedures were modified conform to the following principles. The tip of the frontalis muscle flap included soft tissue that was as thick as possible and the soft tissue on the tarsal plate was removed to the greatest extent possible. A double fold was created in cases of unilateral ptosis. In order to evaluate the objective effects of modification, preoperative and postoperative values of the marginal distance reflex 1 (MRD1), the corneal exposure area, and the decrease in eyebrow height were compared between the two groups. Results In group A, patients showed an improvement of 1.19 mm in the MRD1, a 6.31% improvement in the corneal exposure area, and a 7.82 mm decrease in eyebrow height. In group B, patients showed an improvement of 2.17 mm in the MRD1, an 8.39% improvement in the corneal exposure area, and an 11.54 mm decrease in eyebrow height. The improvements in group B were significantly greater than those in group A. Conclusions Modified frontalis transfer showed better results than the conventional procedure and provided satisfactory outcomes. PMID:27019810

  13. Overview of Results from the Cassini Magnetospheric Imaging Instrument (MIMI) During the First Year of Operations

    NASA Technical Reports Server (NTRS)

    Krimigis, S. M.; Mitchell, D. G.; Hamilton, D. C.; Krupp, N.; Livi, S.; Roelof, E. C.; Dandouras, J.; Mauk, B. H.; Brandt, J. P.; Paranicas, C.

    2005-01-01

    The MIMI investigation comprises three sensors covering the indicated energy ranges: the Ion and Neutral Camera (INCA) -- 7 keV/nuc 3 Mev) and protons (1.6 < E < 160 Mev) from the back end of the dual field-of-view telescope. The Saturn observation sequences began in January, 2004 and culminated in Saturn Orbit Insertion on July 1, 2004. The MIMI sensors observed substantial activity in interplanetary space for several months prior to SOI, including several interplanetary shocks associated with corotating interaction regions, numerous increases most likely originating from particle streams in the vicinity of the Saturnian bow shock and energetic neutral atoms (ENA) emanating from Saturn s magnetosphere. Results following SOI revealed: a dynamical magnetosphere with a day-night asymmetry and an 11-hour periodicity; several water-product ions (O+, OH+, H2O+), but little N+; inferred quantities of neutral gas sufficient to cause major losses in the trapped ions and electrons in the middle and inner magnetosphere; a Titan exosphere that is a copious source of ENA; INCA imaging through ENA has also revealed a previously unknown radiation belt residing inward of the D-ring that is most likely the result of double charge-exchange between the main radiation belt and the upper layers of Saturn s exosphere. Finally, there is ample evidence for the presence of substorm-like injections of plasma that subsequently corotates for a number of days before dissipating on the night-side magnetotail. The observations will be presented and discussed in the context of current theoretical models.

  14. Donor Age and Corneal Endothelial Cell Loss 5 Years after Successful Corneal Transplantation: Specular Microscopy Ancillary Study Results

    PubMed Central

    2010-01-01

    Objective To determine whether endothelial cell loss 5 years after successful corneal transplantation is related to the age of the donor. Design Multicenter, prospective, double-masked clinical trial. Participants Three hundred forty-seven subjects participating in the Cornea Donor Study who had not experienced graft failure 5 years after corneal transplantation for a moderate-risk condition (principally Fuchs’ dystrophy or pseudophakic corneal edema). Testing Specular microscopic images of donor corneas obtained before surgery and postoperatively at 6 months, 12 months, and then annually through 5 years were submitted to a central reading center to measure endothelial cell density (ECD). Main Outcome Measure Endothelial cell density at 5 years. Results At 5 years, there was a substantial decrease in ECD from baseline for all donor ages. Subjects who received a cornea from a donor 12 to 65 years old experienced a median cell loss of 69% in the study eye, resulting in a 5-year median ECD of 824 cells/mm2 (interquartile range, 613–1342), whereas subjects who received a cornea from a donor 66 to 75 years old experienced a cell loss of 75%, resulting in a median 5-year ECD of 654 cells/mm2 (interquartile range, 538–986) (P [adjusted for baseline ECD] = 0.04). Statistically, there was a weak negative association between ECD and donor age analyzed as a continuous variable (r [adjusted for baseline ECD] = −0.19; 95% confidence interval, −0.29 to −0.08). Conclusions Endothelial cell loss is substantial in the 5 years after corneal transplantation. There is a slight association between cell loss and donor age. This finding emphasizes the importance of longer-term follow-up of this cohort to determine if this relationship affects graft survival. PMID:18387408

  15. Genetic progress resulting from forty-three years of breeding of the carioca common bean in Brazil.

    PubMed

    Barili, L D; Vale, N M; Moura, L M; Paula, R G; Silva, F F; Carneiro, J E S

    2016-01-01

    We aimed to evaluate 40 common bean cultivars recommended by various Brazilian research institutions between 1970 and 2013 and estimate the genetic progress obtained for grain yield and other agronomic traits. Additionally, we proposed a bi-segmented nonlinear regression model to infer the year in which breeding began to show significant gains in Brazil. The experiment was carried out in Viçosa/MG and Coimbra/MG, in the dry and winter seasons of 2013. For this, a randomized complete block design with three replications was employed. The following traits were evaluated: number of pods per plant (NPP); number of seeds per pod (NSP); 1000-seed weight (W1000); grain yield (Yield); plant architecture (Arch); and grain aspect (GA). Genotypic means were estimated over years using linear mixed models, and genetic gains were estimated using bi-segmented nonlinear regression models. In summary, the methodology proposed in the present study indicated that bean breeding programs in Brazil began to influence Yield beginning in 1990, resulting in a gain of 6.74% per year (68.15 kg/ha per year). The years from which estimated genetic progress for NPP (5.62% per year), NSP (4.59% per year), W1000 (2.08% per year), and GA (1.36% per year) began to increase were 1994, 1990, 1989, and 1986, respectively. PMID:27525922

  16. Tank Inspection NDE Results for Fiscal Year 2014, Waste Tanks 26, 27, 28 and 33

    SciTech Connect

    Elder, J.; Vandekamp, R.

    2014-09-29

    Ultrasonic nondestructive examinations (NDE) were performed on waste storage tanks 26, 27, 28 and 33 at the Savannah River Site as a part of the “In-Service Inspection (ISI) Program for High Level Waste Tanks.” No reportable conditions were identified during these inspections. The results indicate that the implemented corrosion control program continues to effectively mitigate corrosion in the SRS waste tanks. Ultrasonic inspection (UT) is used to detect general wall thinning, pitting and interface attack, as well as vertically oriented cracks through inspection of an 8.5 inch wide strip extending over the accessible height of the primary tank wall and accessible knuckle regions. Welds were also inspected in tanks 27, 28 and 33 with no reportable indications. In a Type III/IIIA primary tank, a complete vertical strip includes scans of five plates (including knuckles) so five “plate/strips” would be completed at each vertical strip location. In FY 2014, a combined total of 79 plate/strips were examined for thickness mapping and crack detection, equating to over 45,000 square inches of area inspected on the primary tank wall. Of the 79 plate/strips examined in FY 2014 all but three have average thicknesses that remain at or above the construction minimum thickness which is nominal thickness minus 0.010 inches. There were no service induced reportable thicknesses or cracking encountered. A total of 2 pits were documented in 2014 with the deepest being 0.032 inches deep. One pit was detected in Tank 27 and one in Tank 33. No pitting was identified in Tanks 26 or 28. The maximum depth of any pit encountered in FY 2014 is 5% of nominal thickness, which is less than the minimum reportable criteria of 25% through-wall for pitting. In Tank 26 two vertical strips were inspected, as required by the ISI Program, due to tank conditions being outside normal chemistry controls for more than 3 months. Tank 28 had an area of localized thinning on the exterior wall of the

  17. Twelve Years of Cloud-to-Ground Lightning Characteristics, 1989-2000: Small Scale Results

    NASA Astrophysics Data System (ADS)

    Ely, B. L.; Steiger, S. M.; Phillips, S. E.; Orville, R. E.; Huffines, G. R.

    2001-12-01

    The National Lightning Detection Network recorded over 250 million cloud-to-ground lightning flashes from 1989 to 2000. Analysis of lightning flash density and polarity reveal significant small-scale geographical variations. These variations can occur as broad trends over several hundred kilometers, or as sharp contrasts over as little as a few kilometers. This study focuses on four regions of the United States: the Pacific Coast, Rocky Mountains, Appalachian Mountains, and the Houston Metropolitan area. In the Pacific Coastal region, an interesting geographical variation is found in the percentage of positive lightning. A higher than normal percentage of positive lightning discharges (up to five times the national average) dominates the coastline, but drastically decreases about a hundred kilometers inland. In the Rocky and Appalachian Mountains, observations of lightning flash density reveal two distinct and opposite patterns, despite similar terrain. Although located at about the same latitude, the southern Rockies display a significant increase in flash density over regions of high terrain, while the southern Appalachians show a significant decrease in flash density as elevations increase. Further analysis shows that the pattern in the Southern Rockies is a result of a large number of days with low flash counts, while the pattern in the Appalachians results from a few large events. The top 5 percent of lightning producing days accounted for 28.6 percent of all flashes in the high terrain of Rockies, but 56.9 percent of the total flashes in the Appalachians. Our final area of research concerns the lightning enhancement over the Houston, TX region. Fine scale analysis of this area suggests two leading hypotheses to explain this phenomenon. The first explanation is that the complex coastline of Galveston Bay in combination with the urban heat island alters the wind flow in the Houston area, initiating new thunderstorms directly over the city. The second

  18. Analyzing Exercise Behaviors during the College Years: Results from Latent Growth Curve Analysis

    PubMed Central

    Wittman, Werner

    2016-01-01

    The objective of this study is to analyze changes in the predictors of physical activity behavior among college students. The Theory of Planned Behavior served as its theoretical framework. Methods: Among an initial sample of 417 college students, 195 participants completed a validated questionnaire measuring attitudes, subjective norms, perceived control, intentions and self-reported physical activity, at the beginning and end of each of 3 college semesters. Latent growth curve modeling analyses were conducted to examine the relationships between the trajectories of changes in PA, intentions, attitudes, subjective norms, and perceived control. Results: Good fit indices supported the validity of the proposed longitudinal model (CFI > .97, RMSEA < .05). Changes in perceived control (γ = 0.57) were significantly linked with changes in intentions (p < .05). Perceived control (γ = 0.28) and intention growth (γ = 0.36) predicted behavior changes (p < .05). No gender differences were observed on attitudes, subjective norms and perceived control (p > .10). However, girls tend to have higher growth parameters on intentions and physical activity (p < .05). In summary, intentions and physical activity has significantly increased over 3 college semesters (growth parameters significant at p < .05). Conclusions: This study demonstrated that attitudes and perceived control are key determinants regarding the intentions of being active. On a longer term perspective, future physical activity interventions should focus on the enhancement of students’ perceived control. Such educational context should help in promoting the adoption of an active lifestyle during college. PMID:27124179

  19. Results of Dose Control and Measurement Plans Appliedfor SPEAR3 Commissioning Year (FY04)

    SciTech Connect

    Khater, Hesham; Liu, James; Prinz, Alyssa; Allan, Jim; Rokni, Sayed; /SLAC

    2007-02-12

    Dose control and measurement plans for the SPEAR3 Booster and storage ring have taken place during the SPEAR3 commissioning. The initial commissioning period (SPEAR3 start-up) covered the time period from the beginning of November 2003 to the early part of March 2004. The period from the beginning of March to the beginning of August 2004 has been mostly dedicated to the scientific program. The initial commissioning period was characterized with frequent injection and significantly higher losses. In comparison, the scientific program period was characterized with more stable beam operation with limited number of injections per day and lower beam losses. Three types of dose measurements, passive, active and special measurements, were implemented around the SPEAR3 Booster and storage ring. Based on the expected radiation hazards, several dose control measures were adopted at several stages of the commissioning. In the early stages of commissioning, areas within 4.5 m from the walls of the Booster and storage ring were designated as Radiation Areas (RA). Areas outside RA were classified as Radiologically Controlled Area (RCA). Access to these areas required less training than the radiation areas. A monthly review of the accelerator operation conditions and radiation measurement results were used to determine the changes needed for the RA classification status and associated dose control measures.

  20. Three years of the OCRA methodology in Brazil: critical analysis and results.

    PubMed

    Ruddy, Facci; Eduardo, Marcatto; Edoardo, Santino

    2012-01-01

    The Authors make a detailed analysis of the introduction of the OCRA Methodology in Brazil that started in August 2008 with the launching of the "OCRA Book" translated to Portuguese. They evaluate the importance of the assessment of the exposure of the upper limbs to the risk due to repetitive movements and efforts, according to the national and international legislation, demonstrating the interconnection of the OCRA Methodology with the Regulating Norms of the Ministry of Labor and Work (NRs - MTE), especially with the NR-17 and its Application Manual. They discuss the new paradigms of the OCRA Method in relation to the classic paradigms of the ergonomic knowledge. They indicate the OCRA Method as the tool to be used for the confirmation or not of the New Previdentiary Epidemiologic Nexus NTEP/FAP. The Authors present their conclusions based on the practical results the "participants certified by the OCRA Methodology" achieved in the application on different laboral activities in diverse economic segments, showing the risk reduction and the productivity of the companies. PMID:22316774

  1. Empirically based guidelines for moderate drinking: 1-year results from three studies with problem drinkers.

    PubMed Central

    Sanchez-Craig, M; Wilkinson, D A; Davila, R

    1995-01-01

    OBJECTIVES. The study was conducted to refine guidelines on moderate drinking for problem drinkers, persons whose alcohol use is hazardous or harmful. Information on levels of alcohol intake unlikely to cause problems is useful for health professionals, educators, and policymakers. METHODS. Based on their reports of alcohol-related problems, participants in three studies assessing interventions to reduce heavy drinking (114 men, 91 women) were categorized as "problem-free" or "problem" drinkers at follow-up. Drinking measures were examined to identify patterns separating these outcome categories. RESULTS. Analyses using 95% confidence intervals for means on drinking measures showed that guidelines should be sex-specific. Based on analyses of positive and negative predictive value, sensitivity, and specificity, it is recommended that men consume no more than 4 standard drinks in any day and 16 drinks in any week, and that women consume no more than 3 drinks in any day and 12 drinks in any week. CONCLUSIONS. These guidelines are consistent with those from several official bodies and should be useful for advising problem drinkers when moderation is a valid treatment goal. Their applicability to the general population is unevaluated. PMID:7762717

  2. Hypothyroidism is common in turner syndrome: results of a five-year follow-up.

    PubMed

    El-Mansoury, Mostafa; Bryman, Inger; Berntorp, Kerstin; Hanson, Charles; Wilhelmsen, Lars; Landin-Wilhelmsen, Kerstin

    2005-04-01

    Turner syndrome (TS) is caused by a sex chromosome aberration. The aim was to study the prevalence and incidence of thyroid disease in adults with TS. Women with TS (n = 91; mean age, 37.7 +/- 11 yr) were compared with an age-matched female random population sample (n = 228). At baseline, 15 (16%) TS women were treated for hypothyroidism, and elevated serum TSH was found in another eight (9%). As a result, hypothyroidism was more common in women with TS (25%) than in controls (2%; P < 0.0001). Serum free T4 was lower (P = 0.02), and serum TSH was higher (P < 0.0001) in TS women than in age-matched controls. Of all TS women with hypothyroidism, 10 (43%) had an elevated thyroid peroxidase antibody titer vs. 15 (22%) of those without hypothyroidism (P < 0.05), evenly distributed between the karyotype 45,X and mosaicism. A high body mass index, but not a family history or blood lipids, was associated with hypothyroidism in TS. After the 5-yr follow-up, an additional 11 (16%) developed hypothyroidism, of whom four (36%) had elevated thyroid peroxidase. Altogether, 34 (37%) TS women had hypothyroidism after the 5-yr follow-up. Autoimmune hypothyroidism was common, with an annual incidence of 3.2% in TS. Thyroid function should be checked regularly in TS. PMID:15623818

  3. A 500-year overview and analysis of flood changes in Europe: preliminary results

    NASA Astrophysics Data System (ADS)

    Kiss, Andrea

    2014-05-01

    Long-term flood series can be gained by combining evidence and systematic hydrological observations. Following various already existing local and regional studies, an important aim of the present work is to create a broad European database of long flood chronologies and to use them for detecting changes in flood regimes with respect to common break points. Another aim of the investigations is to reveal the main causes (e.g. atmospheric, human) of these changes and study spatial and temporal variability of floods on a European scale. In the presentation we provide an overview on the current stage of these Europe-wide investigations, including the available source types (i.e. documentary and instrumental), geographical coverage, temporal and spatial distribution of long-term flood series applied in the study. The first research results concerns basic information on magnitude, frequency and seasonality of floods (with special consideration of detectable changes). Full list of authors in alphabetic order: Mariano Barriendos (1), Günter Blöschl (2), Rudolf Brázdil (3), Gerardo Benito (4), Chiara Bertolin (5), Dario Camuffo (5), Gaston Demarée (6), Líbor Elleder (7), Silvi Enzi (8), Rüdiger Glaser (9), Julia Hall (2), Andrea Kiss (2), Oldrich Kotyza (10), Carmen Maria del Llasat (1), Neil MacDonald (11), Rui Perdigao (2), Dag Retsö (12), Lars Roald (13), Josep Luis Ruiz Bellet (1), Johannes Schönbeim (9), Petra Schmocker-Fackel (14), Lothar Schulte (1), Hubert Valasek (15), Oliver Wetter (16) (1) Faculty of Geography and History, University of Barcelona, Spain (2) Institute of Hydrological Engineering and Water Resources Management, TU Wien (3) Institute of Geography, Masaryk University Brno, Czech Republic (4) Laboratory of Hydrology and Geomorphology, Center of Env. Sciences, Madrid, Spain (5) Institute of Atmospheric Sciences and Climate, National Research Council, Rome, Italy (6) Royal Meteorological Institute, Brussels, Belgium (7) Research Group of

  4. The ILAN sprite campaigns in Israel: results from 7 years of observations

    NASA Astrophysics Data System (ADS)

    Yair, Yoav; Rubanenko, Lior; Katzenelson, Dor; Rosenthal, Neta; Mezuman, Keren; Price, Colin

    2014-05-01

    The ILAN (Imaging of Lightning And Nocturnal flashes, http://ilanteam.com/) campaigns have been conducted since 2004 from Israel, observing winter thunderstorms in the eastern Mediterranean. We searched for transient luminous events using the standard commercial CCD cameras (Watec N100, 902H2 Ultimate) and the UFO-capture software for event detection, commonly used by other TLE- research groups in Europe and Japan. Winter thunderstorms mostly occur in conjunction with the passage of cold fronts in Cyprus lows, and thus TLEs are best observed when the storms are 200-300 km west of the Israeli coastline, above the Mediterranean Sea. We present statistical analysis of 505 sprites observed in 7 winter campaigns from 2006/7-2012/13. Results show a clear peak in the frequency of sprite detections, with maximum values (above 40% of events) between 00:30-02:50 LST (Local Standard Time, UT+2). This distribution is very different from that of lightning in the region, which peaks ~ 05:00 LST over the sea (Altaratz et al., 2001), hinting at the different temporal behavior of +CG flashes, known to be the major producers of sprites. The morphological distribution of 339 sprites is dominated by column sprites (49.3%) with angels (33.0%) and carrots (25.7%) being less frequent. This is similar to reports of winter sprites over the Sea of Japan (Matsudo et al., 2007). Other shapes (trees, wishbones, etc.; Bór, 2013) appear quite rarely. Single element events constitute 16.8% of observations, with 83.2% containing 2 elements or more. Clusters of homogenous types are slightly more frequent than mixed ones (55%). In some rare cases we observed 12-23 elements in a single sprite. The number of elements and the temporal distribution of different sprite types will be presented and compared with the properties of the parent thunderstorms. Altaratz, O., Levin Z. and Y. Yair, 2001: Winter thunderstorms in Israel - a study with lightning location systems and weather radar. Month. Weath. Rev

  5. Evaluation results after seven years of operation for the permanent Hellenic Seismological Network of Crete (HSNC).

    NASA Astrophysics Data System (ADS)

    Vallianatos, F.; Hloupis, G.; Papadopoulos, I.

    2012-04-01

    The Hellenic arc and the adjacent areas of the Greek mainland are the most active in western Eurasia and some of the most seismically active zones of the world. The seismicity of South Aegean is extremely high and is characterised by the frequent occurrence of large shallow and intermediate depth earthquakes. Until 2004, the installed seismological stations from several providers (NOA, GEOFON, MEDNET) provide average interstation distance around 130km resulting to catalogues with minimum magnitude of completeness (Mc) equals to 3.7. Towards to the direction of providing dense and state of the art instrumental coverage of seismicity in the South Aegean, HSNC begun its operation in 2004. Today it consists of (12) permanent seismological stations equipped with short period and broadband seismographs coupled with 3rd generation 24bit data loggers as well as from (2) accelerographs . The addition of HSNC along with combined use of all the active networks in South Aegean area (NOA, GEOFON, AUTH) decrease the average interstation distance to 60km and provide catalogues with Mc≥3.2. Data transmission and telemetry is implemented by a hybrid network consisting of dedicated wired ADSL links as well as VSAT links by using a unique private satellite hub. Real time data spread over collaborating networks (AUTH) and laboratories (Department of Earth Science - UCL) while at the same time, events are appended automatically and manually to EMSC database. Additional value to the network is provided by means of prototype systems which deployed in-situ for the purposes of: a) Acquiring aftershock data in the minimum time after main event. This is a mobile seismological network called RaDeSeis (Rapid Deployment Seismological network) which consists of a central station acting also as the central communication hub and wifi coupled mobile stations. b) The development of dedicated hardware and software solutions for rapid installation times (around 1 hour for each station) leading to

  6. SOHO celebrates its first year in space with new results on the solar wind

    NASA Astrophysics Data System (ADS)

    1996-12-01

    space, and sees it carrying intermittent bright patches corresponding with relatively dense concentrations of solar material. These gusts are milder than the occasional mass ejections also seen by LASCO, which accompany great convulsions in the solar magnetic field. SOHO's solar wind analyser CELIAS has detected many previously unrecorded elements and isotopes among the charged atoms of the solar wind. The solar wind mapper, SWAN, observes the widespread effects of solar wind particles as they interact with the atoms of an interstellar breeze blowing into the solar system. Yet the results on the solar wind represent only a fraction of SOHO's achievements so far, with twelve sets of instruments observing everything from oscillations deep inside the Sun, to the solar influence on energetic cosmic rays coming from the Galaxy. Stealing the show in helioseismology SOHO is a project of international cooperation between the European Space Agency and NASA. The spacecraft was built in Europe and instrumented by scientists on both sides of the Atlantic. NASA launched SOHO and provides the ground stations and an operations centre at the Goddard Space Flight Center near Washington. SOHO has an uninterrupted view of the Sun from a halo orbit around Lagrangian Point N 1 where the gravity of the Sun and the Earth are in balance, 1,500,000 kilometres out on the sunward side of the Earth. The spacecraft's engineering has proved to be excellent and no practical difficulty is anticipated in keeping SOHO operational into the sunspot maximum expected in 2000-2001. SOHO was launched on 2 December 1995. Check-out observations with some instruments began just a few days later. SOHO attained its L1 halo orbit on 14 February 1996, and commissioning was formally completed on 16 April. Already the first results were showing unprecedented images of the solar atmosphere, of the heliosphere filled by the solar wind, and even of the Sun's interior as revealed by oscillations due to sound waves in the

  7. Double half-cone flap umbilicoplasty for proboscoid umbilical hernia in a 2 years old child with satisfactory results 2 years later

    PubMed Central

    Ashu, Eseme Ebai; Leroy, Guifo Marc; Aristide, Bang Guy; Joss, Bitang Mafok Louis; Bonaventure, Jemea; Patrick, Savom Eric; Myriam, Fotso Guegne

    2015-01-01

    Surgical repair of large umbilical hernias may present a challenging surgical problem; standard surgical techniques have proven to be inadequate for both closing the fascial defect of the umbilicus and providing a satisfactory cosmetic result. We describe here a case of double half-cone flap umbilicoplasty that was performed in a 2 years old boy. The case of a 2 years old child with proboscoid umbilical hernia. The protruding umbilical skin was excised sharply by two V-shaped cuts leaving two half cones, a short cephalic (0.5cm) and a long caudal (1cm). A classic herniotomy was carried out, with repair of the facial defect. The caudal half cone was sutured from its apex till half it's length upon itself with interrupted sutures and it was anchored deeply to the fascia. Then we inverted the cephalic half cone which was sutured to the caudal cone to form the new umbilicus. The early result was excellent with no complications and the result after 2years revealed a cosmetically satisfactory shape of the umbilicus. this technique provides a good solution for reconstruction of the protruding umbilical skin and it is easy to learn, easy to be taught and perform in surgical environments and may be applicable for any kind of umbilical reconstruction. PMID:26664545

  8. 26 CFR 1.960-6 - Overpayments resulting from increase in limitation for taxable year of exclusion.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false Overpayments resulting from increase in limitation for taxable year of exclusion. 1.960-6 Section 1.960-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Controlled Foreign Corporations § 1.960-6 Overpayments resulting...

  9. At a Crossroads: First Results for the 18 to 20-Year-old Cohort of the Youth in Transition Survey

    ERIC Educational Resources Information Center

    Bowlby, Jeffrey W.; McMullen, Kathryn

    2002-01-01

    This report provides a descriptive overview of the first results from the 2000 Youth in Transition Survey (YITS) for 18-20-year-olds in Canada. These early results draw a picture of where youth stand in terms of both their educational participation and attainment and their labour market participation as of December 1999. Youth at this age are in…

  10. [Middle-term result of surgery in 78 cases of complete atrioventricular canal before one year of age].

    PubMed

    Barazer, P Y; Losay, J; Lacour-Gayet, F; Planché, C; Binet, J P

    1989-05-01

    Between 1970 and 1985, 78 children with complete atrioventricular canal were operated upon before the age of one year at the Marie-Lannelongue Surgical Centre. Forty-seven survivors were followed up for periods of 3 months to 13 years after the initial operation; 2 were lost of following. Among the 13 children who survived banding, 1 died spontaneously, 1 had Blalock-Taussig anastomosis and 11 underwent full repair with 5 deaths; out of 6 survivors, 4 are doing well without any treatment, 1 was reoperated upon twice and died during the second operation, and 1 was lost sight of; the survival rates at 5 and 10 years are 46 +/- 23 p. 100 and 29 +/- 23 p. 100 respectively. Among the 34 children who survived an initial complete repair, 2 were reoperated upon 3 months after the repair, with 1 death, 7 subsequently died of infection (6 had trisomy 21); out of 26 survivors followed up for 3 years and 3 months on average after the complete repair (2 to 13 years), 18 show an excellent result and 3 a mediocre result; the survival rates at 5 and 10 years are 45 +/- 9 p. 100 and 30 +/- 27 p. 100 respectively. Whether the patients initially had banding followed by complete repair or complete repair from the start, the probability of survival at 5 and 10 years was the same. The presence of trisomy 21 is an unfavourable prognostic factor at medium-term.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2525372

  11. Biochemical criteria at 1 year are not robust indicators of response to ursodeoxycholic acid in early primary biliary cirrhosis: results from a 29-year cohort study

    PubMed Central

    Papastergiou, V; Tsochatzis, E A; Rodriquez-Peralvarez, M; Thalassinos, E; Pieri, G; Manousou, P; Germani, G; Rigamonti, C; Arvaniti, V; Karatapanis, S; Burroughs, A K

    2013-01-01

    Background In primary biliary cirrhosis (PBC), biochemical criteria at 1 year are considered surrogates of response to ursodeoxycholic acid (UDCA). However, due to the slow natural history of PBC, evaluation at 1 year may be suboptimal to assess the therapeutic response, particularly in early disease. Aim To determine whether evaluation of biochemical criteria at 1 year is a reliable surrogate of UDCA response in early PBC. Methods We analysed the prospectively collected data of 215 patients (untreated = 129; UDCA-treated = 86) with early PBC (normal baseline bilirubin/albumin) and a median follow-up of 8 years (range: 1–29.1). The 1-year attainment rates of the Barcelona, Paris-I, Paris-II and Toronto definitions, and their predictive relevance for a poor outcome (death, transplantation, complications of cirrhosis), were assessed either as a result of UDCA or no treatment. Independent associations with attaining each UDCA response definition were identified by multivariate analysis. Results Untreated patients displayed 1-year biochemical features compatible with ‘treatment response’ at rates (Barcelona: 36.4%, Paris-I: 66.7%, Toronto: 59.7%, Paris-II: 40.3%) similar to those obtained under UDCA. Depending on the definition, baseline ALP≤3xULN (OR: 4.80–35.90), AST≤2xULN (OR: 5.63–9.34) and early histological stage (OR: 3.67–3.87) were the stronger predictors for attaining the criteria. UDCA treatment was associated with attaining Barcelona (OR = 2.16) and Paris-II (OR = 2.84), but not Paris-I, and not Toronto definition when excluding late histological cases. Paris-I criteria were significantly predictive of long-term outcomes (HR = 2.83) in untreated patients. Conclusions In early PBC, biochemical criteria at 1 year reflect severity of the disease rather than the therapeutic response to UDCA. PMID:24117847

  12. RECONSTRUCTION OF THE ANTERIOR CRUCIATE LIGAMENT WITH THE CENTRAL THIRD OF THE QUADRICEPS MUSCLE TENDON: ANALYSIS OF 10-YEAR RESULTS

    PubMed Central

    Guimarães, Marcus Valladares; Junior, Lúcio Honório de Carvalho; Terra, Dalton Lopes

    2015-01-01

    Objective: Assess clinical results using two different protocols, 10 years after ACL reconstruction surgery with the central third of quadriceps muscle tendon (QT). Method: Between November /1997 and April/1998, 25 patients were submitted to 25 ACL reconstructions with QT by transtibial technique. The bone portion of the graft was fixated on femoral tunnel with interference screw and the tendinous portion of tibial tunnel with screw with washer. Two patients injured the new when playing soccer. Six patients were not available for follow-up (24%). Seventeen patients were evaluated, 15 men and two women, with mean age at surgery time of 28.53 ± 6.64 years. All patients were examined at six months, one year, and ten years after surgery. Clinical evaluation was made by the Lysholm scale, and the knee evaluation, with the Hospital for Special Surgery scale. Results: The patients had their injuries operated after 9.87 ± 14.42 months of the accident. According to Lysholm scale, the results at the end of the first year were 98.71 ± 2.47 and, after 10 years, 97.35 ± 3.12. Using the Hospital for Special Surgery scale, the mean score was 95.07 ± 5.23 in one year, and 94.87 ± 4.16 in 10 years. All patients returned to their professional activities with the same previous status. Fifteen (88.24%) patients were able to return to their sports activities, one by modifying the practice, while another one switched to another sport. No patient complained of pain on the donor area in the medium and long term. The sports return rate was excellent, and no changes were found on the femoropatellar joint. PMID:27022511

  13. Field Lysimeter Investigations - test results: Low-Level Waste Data Base Development Program: Test results for fiscal years 1994-1995

    SciTech Connect

    McConnell, J.W. Jr.; Rodgers, R.D.; Hilton, L.D.; Neilson, R.M. Jr.

    1996-06-01

    The Field Lysimeter Investigations: Low-Level Waste Data Base Development Program, funded by the U.S. Nuclear Regulatory Commission (NRC), is (1) studying the degradation effects in EPICOR-II organic ion-exchange resins caused by radiation, (2) examining the adequacy of test procedures recommended in the Branch Technical Position on Waste Form to meet the requirements of 10 CFR 61 using solidified EPICOR-II resins, (3) obtaining performance information on solidified EPICOR-II ion-exchange resins in a disposal environment, and (4) determining the condition of EPICOR-II liners. Results of the final 2 (10 total) years of data acquisition from operation of the field testing are presented and discussed. During the continuing field testing, both portland type I-II cement and Dow vinyl ester-styrene waste forms are being tested in lysimeter arrays located at Argonne National Laboratory-East in Illinois and at Oak Ridge National Laboratory. The experimental equipment is described and results of waste form characterization using tests recommended by the NRC`s {open_quotes}Technical Position on Waste Form{close_quotes} are presented. The study is designed to provide continuous data on nuclide release and movement, as well as environmental conditions, over a 20-year period. At the end of the tenth year, the experiment was closed down. Examination of soil and waste forms is planned to be conducted next and will be reported later.

  14. Evaluation of the results from arthroscopic surgical treatment of rotator cuff injuries in patients aged 65 years and over☆

    PubMed Central

    Miyazaki, Alberto Naoki; da Silva, Luciana Andrade; Santos, Pedro Doenux; Checchia, Sergio Luiz; Cohen, Carina; Giora, Taís Stedile Busin

    2015-01-01

    Objectives To evaluate the results from arthroscopic surgical treatment of rotator cuff injuries in patients aged 65 years and over. Methods Between 1998 and 2009, 168 patients underwent operations. Five cases were excluded. The remaining 163 patients were stratified according to their age group: 65–69 years (49.1%), 70–74 (26.4%) and 75 years and over (24.5%). Their mean age was 71 years (range: 65–83). There were 63 male patients (38.7%). The mean length of time with pain, from the onset of symptoms to the surgery, was 23 months (range: 2 days to 240 months). Sixty-two patients (38%) reported histories of trauma and 26 (16%) reported that their pain worsened through exertion. Results From the UCLA criteria, 80.4% of the results were excellent, 16% good, 1.8% fair and 1.8% poor. Complications occurred in 11%. The final clinical result did not show any correlation with age progression, injury size or tendons affected. However, there was a significant association (p < 0.001) between the presence of trauma and larger injuries. The length of time between the onset of symptoms and the surgical procedure had a significant relationship (p < 0.027) with the postoperative results: the longer this time was, the worse the results were. Conclusion Arthroscopic treatment of rotator cuff injuries in patients aged 65 years and over presented excellent and good results in 96.4% of the cases, according to the UCLA assessment, with a low complication rate. Advanced age did not show any influence on the postoperative clinical evolution, but the earlier the surgical treatment was instituted, the better the results were. PMID:26229935

  15. A Year in Space: Early Results and Lessons Learned from the First Year-Long Expedition Aboard the International Space Station

    NASA Technical Reports Server (NTRS)

    Charles, J. B.; Bogomolov, V. V.

    2016-01-01

    the astronaut and cosmonaut to perform rudimentary tasks requiring sensorimotor coordination immediately after landing to define human capabilities soon after landing on Mars after an extended transit. Both investigations were highly successful in large part to the thorough integration of the implementation processes of the two partners. Kelly's assignment as the one-year crewmember also provided a serendipitous opportunity for the "Twins Study" comparing changes in his body at the genetic level with those occurring on Earth in his identical twin brother Mark Kelly. Data analysis from this expedition will commence in earnest after frozen in-flight samples are delivered to Earth in May aboard a commercial cargo spacecraft. Detailed results are expected in early 2017. Preliminary results and implementation improvements will be reviewed in this presentation.

  16. The Contribution of the Responsive Classroom Approach on Children's Academic Achievement: Results from a Three Year Longitudinal Study

    ERIC Educational Resources Information Center

    Rimm-Kaufman, Sara E.; Fan, Xitao; Chiu, Yu-Jen; You, Wenyi

    2007-01-01

    This paper reports the results of a quasi-experimental study on the contribution of the Responsive Classroom ("RC") Approach to elementary school children's reading and math performance over one-, two-, and three-year periods. All children enrolled in six schools (3 intervention and 3 control schools in a single district) were the participants in…

  17. 26 CFR 1.960-6 - Overpayments resulting from increase in limitation for taxable year of exclusion.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 10 2011-04-01 2011-04-01 false Overpayments resulting from increase in limitation for taxable year of exclusion. 1.960-6 Section 1.960-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Controlled Foreign Corporations § 1.960-6...

  18. Comprehensive Employment and Training Act. Review and Oversight. Part I: Background and First Year Results. Part II: Public Policy Issues.

    ERIC Educational Resources Information Center

    Employment and Training Administration (DOL), Washington, DC.

    This report reviews the establishment and early performance of the comprehensive manpower system established by the Comprehensive Employment and Training Act (CETA). The report is divided into two major sections. Part 1 examines the background and first year results of the CETA program. The legislative and programmatic antecedents to CETA are…

  19. Simple Cognitive and Behavioural Changes Resulting from Improved Physical Fitness in Persons over 50 Years of Age.

    ERIC Educational Resources Information Center

    Stacey, C.; And Others

    1985-01-01

    Evaluates the effects of exercise on simple cognitive performance and on psychological well-being in persons over 50 years of age. It also assesses the relationship between a set of subject variables and dropout from fitness programs. Results suggest that the beneficial effects of exercise may extend to cognitive and personality processes.…

  20. Student's Booklet; To Accompany The Career Data Book: Results from Project TALENT'S Five-Year Follow-Up Study.

    ERIC Educational Resources Information Center

    Flanagan, John C.; And Others

    The Student Booklet is a companion document to "The Career Data Book: Results from Project TALENT'S Five-year Followup Study" (CE 000 755). The booklet's purpose is to enable the high school student to compare his abilities, achievements, interests, and background with those of other young people who went into various occupations so he may be…

  1. What’s Causing Toxicity in Sediments? Results of Twenty Years of Toxicity Identification and Evaluations (TIEs)

    EPA Science Inventory

    Sediment Toxicity Identification and Evaluation (TIEs) methods have been used for twenty years to identify the causes of toxicity in sediments around the world. We summarized and categorized results of more than 80 peer-reviewed TIE studies into non-ionic organic, cationic, ammo...

  2. Splitting Reexamined: Results from a Three-Year Longitudinal Study of Children in Grades Three to Five.

    ERIC Educational Resources Information Center

    Confrey, Jere; Scarano, Grace Hotchkiss

    This paper is a report on the results of a 3-year teaching experiment conducted in Ithaca, New York, introducing students to the concepts of multiplication, division, and ratio as a trio, and to ratio and proportion in a project-based curriculum with heterogeneous grouping. Fractions were introduced as a subset of ratio and proportion. The paper…

  3. 75 FR 13257 - Carbazole Violet Pigment 23 from India: Final Results of the Expedited Five-year (Sunset) Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... Pigment 23 (CVP-23) ] from India pursuant to section 751(c) of the Tariff Act of 1930, as amended (the Act). See Initiation of Five-year (Sunset) Review, 74 FR 56593 (November 2, 2009) (Initiation Notice). On... International Trade Administration Carbazole Violet Pigment 23 from India: Final Results of the Expedited...

  4. Mid-to long-term results of revision total hip replacement in patients aged 50 years or younger.

    PubMed

    Lee, P T H; Lakstein, D L; Lozano, B; Safir, O; Backstein, J; Gross, A E

    2014-08-01

    Revision total hip replacement (THR) for young patients is challenging because of technical complexity and the potential need for subsequent further revisions. We have assessed the survivorship, functional outcome and complications of this procedure in patients aged < 50 years through a large longitudinal series with consistent treatment algorithms. Of 132 consecutive patients (181 hips) who underwent revision THR, 102 patients (151 hips) with a mean age of 43 years (22 to 50) were reviewed at a mean follow-up of 11 years (2 to 26) post-operatively. We attempted to restore bone stock with allograft where indicated. Using further revision for any reason as an end point, the survival of the acetabular component was 71% (sd 4) and 54% (sd 7) at ten- and 20 years. The survival of the femoral component was 80% (sd 4) and 62% (sd 6) at ten- and 20 years. Complications included 11 dislocations (6.1%), ten periprosthetic fractures (5.5%), two deep infections (1.1%), four sciatic nerve palsies (2.2%; three resolved without intervention, one improved after exploration and freeing from adhesions) and one vascular injury (0.6%). The mean modified Harris Hip Score was 41 (10 to 82) pre-operatively, 77 (39 to 93) one year post-operatively and 77 (38 to 93) at the latest review. This overall perspective on the mid- to long-term results is valuable when advising young patients on the prospects of revision surgery at the time of primary replacement. PMID:25086120

  5. Communication Between Breast Cancer Patients Who Received Inconclusive Genetic Test Results and Their Daughters and Sisters Years After Testing.

    PubMed

    Baars, Jessica E; Ausems, Margreet G E M; van Riel, Els; Kars, Marijke C; Bleiker, Eveline M A

    2016-06-01

    Inconclusive genetic test results including screening recommendations for the breast cancer patients and their first-degree relatives are the most common outcomes of BRCA 1/2 testing. Patients themselves should communicate these results to their relatives. Our aim was to explore communication of breast cancer genetic counseling results with daughters and sisters over a long period of time. Breast cancer patients, who had received an inconclusive DNA test result 7-14 years earlier, completed a self-report questionnaire. Additionally, in-depth interviews were conducted and analysed thematically. Of the 93 respondents, 85 (91 %) considered themselves responsible for communicating genetic test results to relatives. In-depth interviews (n = 14) showed, that counselees wanted 'to hand over' their responsibilities to communicate the test results and screening recommendations to their sisters. Although most patients had informed their daughters and sisters about the genetic test results, usually little is spoken about genetic test results and screening recommendations once the duty of informing is completed. We recommend that, similar to the procedure for BRCA1/2-mutation carriers, a separate letter for first-degree relatives of patients with an inconclusive test result should be provided. In this way information about risks and screening recommendations can be verified by family members years after genetic testing has been completed. PMID:26446011

  6. Intermediate clinical and radiological results of cervical TDR (Mobi-C®) with up to 2 years of follow-up

    PubMed Central

    Beaurain, J.; Bernard, P.; Dufour, T.; Fuentes, J. M.; Hovorka, I.; Huppert, J.; Steib, J. P.; Vital, J. M.; Aubourg, L.

    2009-01-01

    The interest in cervical total disc replacement (TDR) as an alternative to the so-far gold standard in the surgical treatment of degenerative disc disease (DDD), e.g anterior cervical discectomy and fusion (ACDF), is growing very rapidly. Many authors have established the fact that ACDF may result in progressive degeneration in adjacent segments. On the contrary, but still theoretically, preservation of motion with TDR at the surgically treated level may potentially reduce the occurrence of adjacent-level degeneration (ALD). The authors report the intermediate results of an undergoing multicentre prospective study of TDR with Mobi-C® prosthesis. The aim of the study was to assess the safety and efficacy of the device in the treatment of DDD and secondary to evaluate the radiological status of adjacent levels and the occurrence of ossifications, at 2-year follow-up (FU). 76 patients have performed their 2-year FU visit and have been analyzed clinically and radiologically. Clinical outcomes (NDI, VAS, SF-36) and ROM measurements were analyzed pre-operatively and at the different post-operative time-points. Complications and re-operations were also assessed. Occurrences of heterotopic ossifications (HOs) and of adjacent disc degeneration radiographic changes have been analyzed from 2-year FU X-rays. The mean NDI and VAS scores for arm and neck are reduced significantly at each post-operative time-point compared to pre-operative condition. Motion is preserved over the time at index levels (mean ROM = 9° at 2 years) and 85.5% of the segments are mobile at 2 years. HOs are responsible for the fusion of 6/76 levels at 2 years. However, presence of HO does not alter the clinical outcomes. The occurrence rate of radiological signs of ALD is very low at 2 years (9.1%). There has been no subsidence, no expulsion and no sub-luxation of the implant. Finally, after 2 years, 91% of the patients assume that they would undergo the procedure again. These intermediate

  7. Field lysimeter investigations - test results. Low-level waste data base development program: Test results for fiscal years 1986, 1987, 1988, and 1989

    SciTech Connect

    McConnell, J.W. Jr.; Rogers, R.D.; Findlay, M.W.; Davis, E.C.; Jastrow, J.D.; Neilson, R.M. Jr.; Hilton, L.D.

    1995-05-01

    The Field Lysimeter Investigations: Low-Level Waste Data Base Development Program, funded by the U.S. Nuclear Regulatory Commission (NRC), is (a) studying the degradation effects in EPICOR-II organic ion-exchange resins caused by radiation, (b) examining the adequacy of test procedures recommended in the Branch Technical Position on Waste Form to meet the requirements of 10 CFR 61 using solidified EPICOR-II resins, (c) obtaining performance information on solidified EPICOR-II ion-exchange resins in a disposal environment, and (d) determining the condition of EPICOR-II liners. Results of the first 4 years of data acquisition from the field testing are presented and discussed. During the continuing field testing, both Portland type I-II cement and Dow vinyl ester-styrene waste forms are being tested in lysimeter arrays located at Argonne National Laboratory-East in Illinois and at Oak Ridge National Laboratory. The experimental equipment is described and results of waste form characterization using tests recommended by the NRC`s {open_quotes}Technical Position on Waste Form{close_quotes} are presented. The study is designed to provide continuous data on nuclide release and movement, as well as environmental conditions, over a 20-year period.

  8. Field Lysimeter Investigations -- Test results. Low-Level Waste Data Base Development Program: Test results for fiscal years 1990, 1991, 1992, and 1993; Volume 2

    SciTech Connect

    McConnell, J.W. Jr.; Rogers, R.D.; Brey, R.R.; Neilson, R.M. Jr.; Hilton, L.D.; Jastrow, J.D.; Wickliff Hicks, D.S.; Sanford, W.E.; Sullivan, T.M.

    1995-12-01

    The Field Lysimeter Investigations: Low-Level Waste Data Base Development Program, funded by the US Nuclear Regulatory Commission (NRC), is (a) studying the degradation effects in EPICOR-II organic ion-exchange resins caused by radiation, (b) examining the adequacy of test procedures recommended in the Branch Technical Position on Waste Form to meet the requirements of 10 CFR 61 using solidified EPICOR-II resins, (c) obtaining performance information on solidified EPICOR-II ion-exchange resins in a disposal environment, and (d) determining the condition of EPICOR-II liners. Results of the second 4 years of data acquisition from the field testing are presented and discussed. During the continuing field testing, both portland type 1--2 cement and Dow vinyl ester-styrene waste forms are being tested in lysimeter arrays located at Argonne National Laboratory-East in Illinois and at Oak Ridge National Laboratory. The experimental equipment is described and results of waste form characterization using tests recommended by the NRC`s ``Technical Position on Waste Form`` are presented. The study is designed to provide continuous data on nuclide release and movement, as well as environmental conditions, over a 20-year period.

  9. Total Knee Arthroplasty Using a Posterior Cruciate Ligament Sacrificing Medial Pivot Knee: Minimum 5-year Follow-up Results

    PubMed Central

    Youm, Yoon-Seok; Lee, Seon-Ho; Cho, Hye-Yong

    2014-01-01

    Purpose To evaluate minimum 5-year follow-up clinical and radiological results of total knee arthroplasty (TKA) using a posterior cruciate ligament sacrificing (PS), non-substituting Advance Medial Pivot Knee. Materials and Methods One hundred and twenty knees in 80 patients who could be followed up for more than 5 years after TKA using the PS Advance Medial Pivot Knee were evaluated retrospectively. The evaluations included the preoperative and postoperative range of motion (ROM), tibiofemoral angle, Knee Society (KS) knee and function scores, and Western Ontario and McMaster Universities Arthritis Index (WOMAC) score. The Kaplan-Meier method was used for survival analysis. Results The ROM increased from a preoperative mean flexion contracture of 7.6° and further flexion of 115.1° to a postoperative mean flexion contracture of 1.5° and further flexion of 120.5°. The tibiofemoral angle was changed from 4.6° varus preoperatively to 5.8° valgus postoperatively. The KS knee and function scores as well as WOMAC score significantly improved after surgery (p<0.05). Complications developed in 4 cases (3.3%): 2 cases of periprosthetic patellar fracture (1.7%) and 2 cases of aseptic loosening (1.7%). The seven-year survival rate was 98.1% in the Kaplan-Meier survival analysis. Conclusions The minimum 5-year follow-up results of TKA using the PS Medial Pivot Knee were satisfactory. PMID:25229042

  10. One-Year Results of the BeweegKuur Lifestyle Intervention Implemented in Dutch Primary Healthcare Settings

    PubMed Central

    Schutte, Bianca A. M.; Haveman-Nies, Annemien; Preller, Liesbeth

    2015-01-01

    Background. Lifestyle interventions focusing on healthy diet and physical activity (PA) are effective in reducing health risks in controlled research settings. The aim of this study was to investigate the one-year results of the BeweegKuur lifestyle intervention implemented nationwide in Netherlands for people with a weight-related health risk. Materials and Methods. Data were requested from all 160 locations participating in the BeweegKuur. In a one group pretest/posttest study, one-year changes in health outcome variables and time spent on physical activity were tested with dependent t-tests. Associations between one-year changes in weight and waist circumference and sociodemographic factors and uptake of the program were analysed with ANOVA. Results. Data for 517 participants from 47 locations were available for analysis. One year after the intervention, weight reduced by 2.9 kg (95% CI −3.3;, −2.5), waist circumference by 4.3 cm (−4.9; −3.7), and blood glucose by 0.5 mmol/L (−0.8; −0.3). Physical activity increased significantly. Higher uptake of the program was associated with a larger decrease in waist circumference. Conclusion. The results of the study suggest that lifestyle interventions implemented in real-life primary healthcare settings with tailor-made supervision can contribute meaningfully to primary prevention. PMID:26380276

  11. Bactercline®-coated implants: Clinical results up to 1 year after loading from a controlled clinical trial

    PubMed Central

    Carinci, Francesco; Grecchi, Emma; Bignozzi, Carlo Alberto; Murmura, Giovanna; Piattelli, Adriano; Scarano, Antonio

    2012-01-01

    Background: Titanium dioxide exists in three different crystal lattices, anatase, rutile, and brookite. Anatase coating releases, under ultraviolet (UV) irradiation, free radicals such as ·OH, O2-, HO2-, and H2O2. This potent oxidizing power characteristically results in the lysis of bacteria and other organic substances. The purpose of this study was to evaluate the bone response to implants made of titanium alloy or coated with a new combination of anatase and Bactercline® product. Materials and Methods: In the period between July 2009 and June 2010, 26 patients (10 females and 16 males; median age 51 ± 11 years, min. 27 years, max. 72 years) were operated and 62 implants were inserted. Lost fixtures and peri-implant bone resorption were considered as predictors of clinical outcomes. Pearson χ2-test was used. Prosthesis and implant failures, any complications after loading, and peri-implant marginal bone-level changes were assessed by a masked assessor. All patients were followed up to 1 year after loading. Results: No implant was lost. Average bone resorption around implant was 0.33 mm (both for 25 standard and 37 Bactercline-coated implants), and thus no statistical difference was detected. Conclusion: These results shown that no adverse effects on osseo-integration were present. PMID:23814572

  12. Results after beta-irradiation (/sup 106/Ru//sup 106/Rh) of choroidal melanomas. Twenty years' experience

    SciTech Connect

    Lommatzsch, P.K.

    1987-04-01

    For two decades, from 1964 to 1984, 309 patients suffering from choroidal melanoma were treated with /sup 106/Ru//sup 106/Rh applications, following confirmation of diagnosis by a variety of tests. A total of 216 patients (69.9%) were treated successfully and have been under observation for a mean period of 6.7 years after irradiation. 188 patients were followed for more than five years. Results indicate that enucleation for choroidal melanoma, especially in cases of eyes with good vision, may no longer be the standard treatment for this disease. This appears particularly true inasmuch as almost 50% of all patients with large choroidal melanomas who have enucleation die from metastases within 5 years of the operation. Therefore, conservative methods such as photocoagulation, irradiation, and microsurgical excision have been used with more or less success to destroy tumor and save a functioning eye.

  13. Aging of Polyurethane Foam Insulation in Simulated Refrigerator Panels--One-Year Results with Third-Generation Blowing Agents

    SciTech Connect

    Gabbard, W.A.; Weaver, F.J.; Wilkes, K.E.

    1999-09-27

    Laboratory data are presented on the effect of constant-temperature aging on the apparent thermal conductivity of polyurethane foam insulation for refrigerators and freezers. The foam specimens were blown with HCFC-141b and with three of its potential replacements--HFC-134a, HFC-245fa, and cyclopentane. Specimens were aged at constant temperatures of 90 F, 40 F, and {minus}10 F. Thermal conductivity measurements were made on two types of specimens: full-thickness simulated refrigerator panels containing foam enclosed between solid plastic sheets, and thin slices of core foam cut from similar panels. Results are presented for the first year of a multi-year study for the full-thickness panels and for about 1-1/2 years of aging for the core-foam specimens.

  14. Results from the second year of operation of the Federal Methanol Fleet at Oak Ridge National Laboratory

    SciTech Connect

    West, B.H.; McGill ); Hillis, S.L. )

    1990-09-01

    The Oak Ridge National Laboratory has completed its second year of operation of ten vehicles for the Federal Methanol Fleet Project; five of the vehicles are fueled with methanol. Over 56,000 miles were accumulated on the vehicles in the second year bringing the total to over 152,000 miles. Energy consumption for the methanol cars was slightly higher than that of the gasoline cars again this year, most likely as a result of shorter average trip lengths for the methanol gas. Iron and lead have accumulated at greater rates in the lubricating oil of the methanol cars. Driver's ratings of vehicles reflected some dissatisfaction with the cold-weather performance of the methanol cars, but the cars have no special provisions for cold weather starting, and the fuel vapor pressure has not been tailored to the season as at other test sites. Otherwise, drivers' opinions of the methanol cars have been favorable. 13 refs., 4 figs., 10 tabs.

  15. How healthy are chronically ill patients after eight years of homeopathic treatment? – Results from a long term observational study

    PubMed Central

    Witt, Claudia M; Lüdtke, Rainer; Mengler, Nils; Willich, Stefan N

    2008-01-01

    Background Homeopathy is a highly debated but often used medical treatment. With this cohort study we aimed to evaluate health status changes under homeopathic treatment in routine care. Here we extend former results, now presenting data of an 8-year follow-up. Methods In a prospective, multicentre cohort study with 103 homeopathic primary care practices in Germany and Switzerland, data from all patients (age >1 year) consulting the physician for the first time were observed. The main outcome measures were: The patients' perceived change in complaint severity (numeric rating scales from 0 = no complaint to 10 = maximal severity) and quality of life as measured by the SF-36 at baseline, and after 2 and 8 years. Results A total of 3,709 patients were studied, 73% (2,722 adults, 72.8% female, age at baseline 41.0 ± 12.3; 819 children, 48.4% female, age 6.5 ± 4.0) contributed data to the 8-year follow-up. The most frequent diagnoses were allergic rhinitis and headache in adults, and atopic dermatitis and multiple recurrent infections in children. Disease severity decreased significantly (p < 0.001) between baseline, 2 and 8 years (adults from 6.2 ± 1.7 to 2.9 ± 2.2 and 2.7 ± 2.1; children from 6.1 ± 1.8 to 2.1 ± 2.0 and 1.7 ± 1.9). Physical and mental quality of life sores also increased considerably. Younger age, female gender and more severe disease at baseline were factors predictive of better therapeutic success. Conclusion Patients who seek homeopathic treatment are likely to improve considerably. These effects persist for as long as 8 years. PMID:19091085

  16. Does cognitive impairment influence outcomes from cataract surgery? Results from a 1-year follow-up cohort study

    PubMed Central

    Jefferis, Joanna Mary; Taylor, John-Paul; Clarke, Michael Patrick

    2015-01-01

    Background/aims To assess the impact of impaired cognition on visual outcomes 1 year following cataract surgery in a cohort of older people. Methods Participants aged 75 years or more with bilateral cataract and scheduled for cataract surgery were recruited consecutively. Cognition was assessed using the revised Addenbrooke's cognitive examination (ACE-R). Participants were divided into two groups: normal (ACE-R ≥88) and impaired cognition (ACE-R <88). Visual quality of life (VQOL) and logarithm of minimum angle of resolution visual acuity (VA) were assessed at baseline and 1 year following cataract surgery. Results Of 112 participants, 48 (43%) had normal cognition and 64 (57%) had impaired cognition. One year following cataract surgery participants in both groups had significant improvements in VQOL and VA. Visual outcomes at 1 year were significantly better in participants with normal cognition than in those with impaired cognition (95% CIs for difference 0.4–7.0 and 0.02–0.1, for VQOL and VA, respectively). Regression analyses correcting for potential confounders showed a relationship between baseline cognition and VA at 1 year (R2=0.30, p=0.001) and a possible relationship between baseline cognition and VQOL at 1 year (R2=0.41, p=0.01, this became insignificant after removal of outliers). Conclusions Patients with impaired cognition benefit from cataract surgery, but not to the same extent as patients with normal cognition. PMID:25287367

  17. Ten-Year Results From the Natrelle 410 Anatomical Form-Stable Silicone Breast Implant Core Study

    PubMed Central

    Maxwell, G. Patrick; Van Natta, Bruce W.; Bengtson, Bradley P.; Murphy, Diane K.

    2015-01-01

    Background Silicone breast implants have long been used for breast augmentation and reconstruction. During this time, these medical devices have gone through a number of modifications to improve their safety, quality, and clinical outcome performance. Objectives The authors conducted a 10-year study to determine the safety and effectiveness of Natrelle 410 silicone breast implants. Methods This prospective, multicenter study enrolled 941 subjects who were undergoing either augmentation, augmentation revision, reconstruction, or reconstruction revision. Data on complications, reoperations, explantations, and subject satisfaction were collected at annual clinic visits, and one-third of subjects underwent biennial magnetic resonance imaging (MRI) to screen for implant rupture. The authors used the Kaplan-Meier estimator to calculate risk rates for local complications, reoperations, and explantations. Results Capsular contracture rates increased approximately 1% per year from the previously reported 6-year rates. The rates were significantly lower than those from the Natrelle round gel core study. The overall rate of confirmed ruptured implants in subjects who underwent MRI was 5.7%. Eleven late seromas were reported. The most common reason for explantation was a subject requesting a size or style change. Satisfaction rates remained high through 10 years, with most subjects saying they were somewhat or definitely satisfied with their implants. Conclusions This 10-year prospective trial demonstrated the long-term safety and effectiveness of Natrelle 410 anatomical form-stable implants. The complication rates were low and the satisfaction rates were high. Level of Evidence: 1 Therapeutic PMID:25717116

  18. Geology of Libya Montes and the Interbasin Plains of Northern Tyrrhena Terra, Mars: First Year Results and Second Year Work Plan

    NASA Technical Reports Server (NTRS)

    Skinner, J. A., Jr.; Rogers, A. D.; Seelos, K. D.

    2010-01-01

    The Libya Montes-Tyrrhena Terra highland-lowland transitional zone of Mars is a complex tectonic and erosional region that contains some of the oldest exposed materials on the Martian surface as well as aqueous mineral signatures that may be potential chemical artifacts of early highland formational processes. Our 1:1M scale mapping project includes the geologic materials and landforms contained within MTMs 00282, -05282, -10282, 00277, - 05277, and -10277, which cover the highland portion of the transitional zone. The map region extends from the Libya Montes southward into Tyrrhena Terra and to the northern rim of Hellas basin and includes volcanic rocks of Syrtis Major Planum and a broad lowlying plain (palus) that forms a topographic divide between Isidis and Hellas basins. The objective of this project is to describe the geologic history of regional massif and plains materials by combining geomorphological and compositional mapping observations. This abstract summarizes the technical approaches and interim scientific results of Year 1 efforts and the expected work plan for Year 2 efforts.

  19. Hip resurfacing in a district general hospital: 6-year clinical results using the ReCap hip resurfacing system

    PubMed Central

    2012-01-01

    Background The purpose of our study was to prospectively report the clinical results of 280 consecutive hips (240 patients) who received a ReCap Hip Resurfacing System implant (Biomet Inc., Warsaw, USA) in a single district general hospital. Literature reports a large variation in clinical results between different resurfacing designs and published results using this particular design are scarce. Methods Mean follow up was 3.3 years (1.0 to 6.3) and four patients were lost to follow-up. All patients were diagnosed with end-stage hip osteoarthritis, their mean age was 54 years and 76.4% of all patients were male. Results There were 16 revisions and four patients reported a Harris Hip Score <70 points at their latest follow up. There were no pending revisions. Kaplan-Meier implant survival probability, with revision for any reason as endpoint, was 93.5% at six years follow-up (95%-CI: 88.8-95.3). There were no revisions for Adverse Reactions to Metal Debris (ARMD) and no indications of ARMD in symptomatic non-revised patients, although diagnostics were limited to ultrasound scans. Conclusions This independent series confirms that hip resurfacing is a demanding procedure, and that implant survival of the ReCap hip resurfacing system is on a critical level in our series. In non-revised patients, reported outcomes are generally excellent. Trial registration ClinicalTrials.gov Identifier: NCT00603395 PMID:23234268

  20. Two- to Four-Year Follow-up Results of Total Knee Arthroplasty Using a New High-Flexion Prosthesis

    PubMed Central

    Kim, Man Soo; Koh, In Jun; Jang, Sung Won; Jeon, Neung Han

    2016-01-01

    Purpose The purpose of this study was to evaluate minimum 2-year follow-up results of total knee arthroplasty (TKA) performed using a new high-flexion prosthesis design (LOSPA). Materials and Methods The 2- to 4-year results of 191 consecutive TKAs (177 patients) with the LOSPA posterior-stabilized prosthesis were evaluated. The patients were assessed clinically and radiographically using the Knee Society scoring system (KSS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results The mean range of motion (ROM) increased significantly from 117.4° (range, 75° to 140°) preoperatively to 126.7° (range, 80° to 144°) postoperatively (p<0.001). The mean KSS and WOMAC scores improved significantly from 121.4 (range, 42 to 185) and 56.1 (range, 23 to 88) preoperatively to 174.0 (range, 130 to 200) and 16.4 (range, 0 to 85) postoperatively, respectively (both, p<0.001). One knee required revision for deep infection. No knee had aseptic loosening or osteolysis. Radiolucent lines were noted in 15 knees (7.9%). Conclusions The new high-flexion total knee prosthesis resulted in no early aseptic loosening of the component and improved postoperative ROM comparable to other high-flexion TKA prostheses at 2- to 4-year follow-ups. PMID:26955612

  1. A PROSPECTIVE STUDY OF ALTERNATING OCCLUSION PRIOR TO SURGICAL ALIGNMENT FOR INFANTILE ESOTROPIA: ONE-YEAR POSTOPERATIVE MOTOR RESULTS

    PubMed Central

    Ing, Malcolm R; Norcia, Anthony; Stager, David; Black, Bradley; Hoffman, Robert; Mazow, Malcolm; Troia, Sebastian; Scott, William; Lambert, Scott

    2005-01-01

    Purpose Alternating occlusion prior to surgical alignment has been suggested by some strabismologists to possibly enhance the treatment of infantile esotropia. This report presents the data for 44 patients prospectively enrolled by random assignment to an alternating occlusion or no occlusion subgroup followed for 1 year postoperatively. Methods All patients were measured at entry into the study, at the time of surgery, and at 6 weeks and 1 year postoperatively. Alternating occlusion was full-time and symmetric for those with no amblyopia but asymmetric for those with amblyopia. The subgroup that did not receive alternating occlusion had occlusion for amblyopia only. Initial surgeries were performed between the ages of 6 and 13 months. Results The patients, as a whole, showed a significant increase of 9.14 prism diopters when followed for a mean of 4.2 months prior to initial surgery (P < .00027). Seventy-five percent of all patients were aligned by the initial surgery. Ninety-one percent of those patients aligned at 6 weeks were also aligned at the 1-year postoperative date. The results were similar for both the control group and the patients treated with alternating occlusion. Conclusion In our sample of patients, alternating occlusion does not detectably alter the increase in angle of deviation between the dates of entry and the date of the initial surgical alignment procedure, nor does it influence the postoperative alignment at 6 weeks or at 1 year. PMID:17057785

  2. EVALUATION OF THE RESULTS FROM ARTHROSCOPIC REPAIR ON ROTATOR CUFF INJURIES AMONG PATIENTS UNDER 50 YEARS OF AGE

    PubMed Central

    Miyazaki, Alberto Naoki; Fregoneze, Marcelo; Santos, Pedro Doneux; da Silva, Luciana Andrade; do Val Sella, Guilherme; Santos, Ruy Mesquita Maranhão; de Souza, Adriano; Checchia, Sérgio Luiz

    2015-01-01

    Objective: To assess the results from arthroscopic surgical treatment of rotator cuff injuries among patients under 50 years of age. Methods: Sixty-three patients with rotator cuff injuries who underwent arthroscopic surgical treatment performed by the Shoulder and Elbow Group of the Department of Orthopedics and Traumatology, in the Fernandinho Simonsen wing of Santa Casa Medical School, São Paulo, between August 1998 and December 2007, were reassessed. The study included all patients with rotator cuff injuries who were under 50 years of age and had been followed up postoperatively for at least 24 months. Results: According to the UCLA evaluation criteria, 59 patients (92%) showed excellent and good results; five (8%) showed fair results; and none showed poor results. The postoperative evaluation showed that the mean range of motion was 145° for elevation, 47° for lateral rotation and T10 for medial rotation. Unsatisfactory results were associated with prolonged duration of the injury, with a statistically significant relationship. Conclusion: Arthroscopic repair of rotator cuff injuries in young patients produces excellent or good results for most patients. PMID:27047819

  3. Biogeochemistry, transport fluxes and emission of greenhouse gases from the Ogooué River (west central Africa): preliminary results after two years of monitoring

    NASA Astrophysics Data System (ADS)

    Darchambeau, François; Bouillon, Steven; Mbega, Jean-Daniel; Lambert, Thibault; Borges, Alberto V.

    2014-05-01

    The Ogooué River is the fourth largest river in Africa by discharge. The Ogooué Basin mostly consists of undisturbed rainforest with some savanna grassland. Yet, there is no information on the biogeochemistry, transport fluxes and greenhouse gases in this river. Here, we report initial results of a monitoring campaign whereby 2-weekly samples were collected at Lambaréné (Gabon) [10.24°E 0.69°S] between April 2012 and March 2014 for a suite of physico-chemical and biogeochemical characteristics, including total suspended matter (TSM) concentrations, concentration and stable isotope composition of particulate organic carbon (POC and δ13C-POC) and particulate nitrogen (PN and δ15N-PN), chromophoric dissolved organic matter (CDOM), dissolved organic carbon (DOC and δ13C-DOC), dissolved inorganic carbon (DIC and δ13C-DIC), concentration of greenhouse gases (GHGs) (CO2, CH4 and N2O), as well as major elements, total alkalinity, and oxygen isotope signatures of water (δ18O-H2O). This dataset allows us to construct annual budgets for particulate and dissolved carbon fluxes, nutrient exports, as well as a first seasonally resolved characterisation of the GHGs emitted to the atmosphere by the Ogooué River.

  4. Percutaneous Nucleoplasty Using Coblation Technique for the Treatment of Chronic Nonspecific Low Back Pain: 5-year Follow-up Results

    PubMed Central

    Ren, Da-Jiang; Liu, Xiu-Mei; Du, Sui-Yong; Sun, Tian-Sheng; Zhang, Zhi-Cheng; Li, Fang

    2015-01-01

    Background: This study evaluated the efficacy of percutaneous nucleoplasty using coblation technique for the treatment of chronic nonspecific low back pain (LBP), after 5 years of follow-up. Methods: From September 2004 to November 2006, 172 patients underwent percutaneous nucleoplasty for chronic LBP in our department. Forty-one of these patients were followed up for a mean period of 67 months. Nucleoplasty was performed at L3/4 in 1 patient; L4/5 in 25 patients; L5/S1 in 2 patients; L3/4 and L4/5 in 2 patients; L4/5 and L5/S1 in 7 patients; and L3/4, L4/5, and L5/S1 in 4 patients. Patients were assessed preoperatively and at 1 week, 1 year, 3 years, and 5 years postoperatively. Pain was graded using a 10-cm Visual Analogue Scale (VAS) and the percentage reduction in pain score was calculated at each postoperative time point. The Oswestry Disability Index (ODI) was used to assess disability-related to lumbar spine degeneration, and patient satisfaction was assessed using the modified MacNab criteria. Results: There were significant differences among the preoperative, 1-week postoperative, and 3-year postoperative VAS and ODI scores, but not between the 3- and 5-year postoperative scores. There were no significant differences in age, sex, or preoperative symptoms between patients with effective and ineffective treatment, but there were significant differences in the number of levels treated, Pfirrmann grade of intervertebral disc degeneration, and provocative discography findings between these two groups. Excellent or good patient satisfaction was achieved in 87.9% of patients after 1 week, 72.4% after 1 year, 67.7% after 3 years, and 63.4% at the last follow-up. Conclusions: Although previously published short- and medium-term outcomes after percutaneous nucleoplasty appeared to be satisfactory, our long-term follow-up results show a significant decline in patient satisfaction over time. Percutaneous nucleoplasty is a safe and simple technique, with therapeutic

  5. Health Risk Factor Modification Predicts Incidence of Diabetes in an Employee Population: Results of an 8-Year Longitudinal Cohort Study

    PubMed Central

    Rolando, Lori; Byrne, Daniel W.; McGown, Paula W.; Goetzel, Ron Z.; Elasy, Tom; Yarbrough, Mary I.

    2013-01-01

    Objective To understand risk factor modification effect on Type 2 Diabetes incidence in a workforce population. Methods Annual Health Risk Assessment (HRA) data (n=3125) in years 1 through 4 were used to predict diabetes development in years 5 through 8. Results Employees who reduced their BMI from ≥30 to < 30 decreased their chances of developing diabetes (OR 0.22, 95% CI 0.05 to 0.93), while those who became obese increased their diabetes risk (OR 8.85, 95% CI 2.53 to 31.0). Conclusions Weight reduction observed over a long period can result in clinically important reductions in diabetes incidence. Workplace health promotion programs may prevent diabetes among workers by encouraging weight loss and adoption of healthy lifestyle habits. PMID:23532193

  6. First report of Actinomyces europaeus bacteraemia result from a breast abscess in a 53-year-old man

    PubMed Central

    Nielsen, H.L.

    2015-01-01

    This is the first report of Actinomyces europaeus bacteraemia in a 53-year-old man. The bacteraemia was the result of a breast abscess. Identification was established by matrix-assisted desorption ionization–time of flight mass spectrometry and confirmed by 16S rRNA gene sequencing. The patient was treated with surgical drainage and penicillin for 4 weeks; the patient did not experience any relapse during 6 months of follow-up. PMID:26110063

  7. Final Results of a 3-Year Literacy-Informed Intervention to Promote Annual Fecal Occult Blood Test Screening.

    PubMed

    Arnold, Connie L; Rademaker, Alfred; Wolf, Michael S; Liu, Dachao; Lucas, Geoffrey; Hancock, Jill; Davis, Terry C

    2016-08-01

    This three arm study was designed to make CRC screening with FOBTs more accessible, understandable and actionable for patients cared for in predominantly rural Federally Qualified Health Centers. Patients in an enhanced version of usual care received an annual CRC recommendation and FOBT kit; those in the education arm additionally received brief literacy and culturally appropriate education and those in the nurse arm received the education by a nurse manager who followed up by telephone. Baseline FOBT rates in this population were 3 %. We evaluated if FOBT rates could be sustained over 3 years. A three-arm, quasi-experimental evaluation was conducted among eight clinics in Louisiana. Screening efforts included: (1) enhanced usual care, (2) literacy-informed education of patients, and (3) education plus nurse support. Overall, 961 average-risk patients, ages 50-85, eligible for routine CRC screenings were recruited. The primary outcome was completing three annual FOBT tests. Of 961 patients enrolled, 381 (39.6 %) participants did not complete a single FOBT, 60.4 % completed at least one FOBT of which 318 (33.1 %) completed only one, 162 (16.9 %) completed two and 100 (10.4 %) completed three FOBTs over the 3-year period (the primary study outcome). The primary outcome, return of three FOBT kits over the 3-year period, was achieved by 4.7 % in enhanced care, 11.4 % in education and 13.6 % in the nurse arm (p = 0.005). Overall 3-year FOBT screening rates were not sustained with any of the three interventions, despite reports of promising interim results at years 1 and 2. New strategies for sustaining FOBT screening over several years must be developed. PMID:26769026

  8. Peri-implant evaluation of osseointegrated implants subjected to orthodontic forces: results after three years of functional loading

    PubMed Central

    Marins, Bruna de Rezende; Pramiu, Suy Ellen; Busato, Mauro Carlos Agner; Marchi, Luiz Carlos; Togashi, Adriane Yaeko

    2016-01-01

    ABSTRACT Objective: The objective of this study was to clinically and radiographically assess the peri-implant conditions of implants used as orthodontic anchorage. Methods: Two groups were studied: 1) a test group in which osseointegrated implants were used as orthodontic anchorage, with the application of 200-cN force; and 2) a control group in which implants were not subjected to orthodontic force, but supported a screw-retained prosthesis. Clinical evaluations were performed three, six and nine months after prosthesis installation and 1- and 3-year follow-up examinations. Intraoral periapical radiographs were obtained 30 days after surgical implant placement, at the time of prosthesis installation, and one, two and three years thereafter. The results were compared by Kruskal-Wallis test. Results: There was no statistically significant difference in clinical probing depth (p = 0.1078) or mesial and distal crestal bone resorption (p = 0.1832) during the study period. After three years of follow-up, the mean probing depth was 2.21 mm for the control group and 2.39 mm for the test group. The implants of the control group showed a mean distance between the bone crest and implant shoulder of 2.39 mm, whereas the implants used as orthodontic anchorage showed a mean distance of 2.58 mm at the distal site. Conclusion: Results suggest that the use of stable intraoral orthodontic anchorage did not compromise the health of peri-implant tissues or the longevity of the implant. PMID:27275618

  9. Carotid Stenting with Distal Protection in High-Surgical-Risk Patients: One-Year Results of the ASTI Trial

    SciTech Connect

    Bosiers, Marc; Scheinert, Dierk; Mathias, Klaus; Langhoff, Ralf; Mudra, Harald; Diaz-Cartelle, Juan

    2015-04-15

    PurposeThis prospective, multicenter, nonrandomized study evaluated the periprocedural and 1-year outcomes in high-surgical-risk patients with carotid artery stenosis treated with the Adapt Carotid Stent plus FilterWire EZ distal protection catheter (Boston Scientific Corporation, Natick, MA).Materials and MethodsThe study enrolled 100 patients (32 symptomatic, 63 asymptomatic, 5 unknown) at high risk for carotid endarterectomy due to prespecified anatomical criteria and/or medical comorbidities. Thirty-day and 1-year follow-up included clinical evaluation, carotid duplex ultrasound, and independent neurologic and NIH stroke scale assessments. One-year endpoints included the composite rate of major adverse events (MAE), defined as death, stroke, and myocardial infarction (MI) and the rates of late ipsilateral stroke (31–365 days), target lesion revascularization, and in-stent restenosis.ResultsOf the 100 enrolled patients, technical success was achieved in 90.9 % (90/99). The 30-day MAE rate (5.1 %) consisted of major stroke (2.0 %) and minor stroke (3.1 %); no deaths or MIs occurred. The 1-year MAE rate (12.2 %) consisted of death, MI, and stroke rates of 4.4, 3.3, and 8.9 %, respectively. Late ipsilateral stroke (31–365 days) rate was 1.1 %. Symptomatic patients had higher rates of death (11.1 vs. 1.7 %) and MI (7.4 vs. 1.7 %), but lower rates of major (7.4 vs. 10.0 %) and minor stroke (0.0 vs. 6.7 %), compared with asymptomatic patients.ConclusionResults through 1 year postprocedure demonstrated that carotid artery stenting with Adapt Carotid Stent and FilterWire EZ is safe and effective in high-risk-surgical patients.

  10. Hydroxyapatite-coated stems with metaphyseal and diaphyseal press-fit. Eleven-year follow-up results.

    PubMed

    Hernández Cortés, P; Nájera Sagastume, O O; Mesa Ramos, F; Pajares López, M; Hernández Hernández, M A

    2002-02-01

    We report the 11-year follow-up results of 52 unilateral primary hip arthroplasties performed with hydroxyapatite-coated stems. The femoral prosthesis used was a collarless titanium alloy implant, with proximal circumferential hydroxyapatite coating and increased distal thickness to fit the proximal diaphyseal region of the femur. Clinical evaluation was performed using the Merle d'Aubigné Hip Score. Anteroposterior and lateral radiographs were obtained and compared with previous postoperative films. Radiographic evaluation was carried out following Engh's criteria for uncemented implant fixation and using Livermore's method for measurement of polyethylene wear. At the end of the follow-up period, excellent and good clinical results were recorded in 40 arthroplasties (77%). The incidence of thigh pain at one year was 32.7%, but it decreased to 4.2% after the first post-operative year. The 11-year survival rate was 92.3%. Seven arthroplasties were revised because of aseptic loosening of the cup in one case, aseptic loosening of the stem, in one case, septic loosening of the stem in one case, periprosthetic fracture in two cases and polyethylene wear in three cases. Forty-two (87.5%) of the nonrevised stems met the criteria for radiographic osseointegration. Cortical hypertrophy was observed around the mid-part and tip of the stem in 22 patients of the series. This sign tends to be related to thigh pain (p < 0.1). Calcar osteolysis was present in 8 cases. There was only one case of distal femoral osteolysis. We found a strong and significant relationship between long-term wear rates and the occurrence of osteolysis (p < 0.001). We concluded that thigh pain is in relation to the distal diameter of the stems and significantly decreases after the first postoperative year. There was a low incidence of osteolysis in our series in comparison with other series of noncemented implants with 32-mm femoral heads and with similar follow-up. PMID:11915455

  11. Effects of a low cholesterol eating plan on plasma lipids: results of a three-year community study.

    PubMed Central

    Reeves, R S; Foreyt, J P; Scott, L W; Mitchell, R E; Wohlleb, J; Gotto, A M

    1983-01-01

    In an attempt to demonstrate whether individuals with average plasma lipids would accept a diet low in saturated fat and cholesterol, members of a community organization were taught the HELP Your Heart Eating Plan. Results of 282 individuals suggest that reduced dietary cholesterol from selected foods could be sustained for up to 36 months. While both plasma cholesterol and triglycerides fell during a year of instruction, both rose to above initial values by 36 months. Overall, the results suggest that adults may be willing to accept a new style of eating temporarily but are not committed to making permanent dietary changes. PMID:6869641

  12. Work Content and Serious Mental Illness among Middle-Aged Men: Results from a 6-Year Longitudinal Study in Japan

    PubMed Central

    Eguchi, Hisashi; Wada, Koji; Higuchi, Yoshiyuki; Yoneoka, Daisuke; Smith, Derek R.

    2015-01-01

    Objective The present study aimed to determine prospective associations between work content after a working life of more than 20 years and serious mental illness among Japanese men aged 50 to 59 years, using a nationwide population-based survey. Methods Data were extracted from a national longitudinal survey of middle-aged and elderly persons previously conducted by the Ministry of Health, Labour and Welfare in Japan. We analyzed data across 10 work content categories for Japanese men who had been working in the same job type or industry for over 20 years. As part pf the survey, participants completed the Kessler (K)6 scale each year to determine their level of psychological distress (with scores ≥13 indicating serious mental illness). Cox discrete time proposal hazard regression analysis was used to examine potential associations between work content and serious mental illness from 2005 to 2010. Further adjustments were made for other sociodemographic characteristics and lifestyle factors. Results The current study involved a total of 11,942 participants with a mean (± standard deviation [SD]) of follow-up was 3.4 (± 2.0) years, during which time 892 participants (7.5%) had been classified as having a new-onset serious mental illness. Men who had worked in service jobs and in manufacturing jobs at baseline were more likely to develop serious mental illness than those in managerial jobs (hazard ratio 1.37, 1.30, 95% confidence intervals 1.04–1.80, 1.02–1.65) after adjustment for confounding variables. Conclusion These findings suggest that Japanese men aged 50 to 59 years who have worked in service and manufacturing jobs after a working life of over 20 years have an increased risk of serious mental illness during follow-up. Identifying the most at-risk work content category after a working life of over 20 years would be an essential part of providing more effective interventions for psychological distress among Japanese men in this age group. PMID:26121355

  13. Excellent results of HA coating on a grit-blasted stem: 245 patients followed for 8-12 years.

    PubMed

    Reikerås, Olav; Gunderson, Ragnhild B

    2003-04-01

    We report the outcome of a grit-blasted titanium stem designed for press-fit insertion and entirely plasma sprayed with HA. During the years 1988-1993, we performed 323 primary total hip replacements in 276 patients (189 women) with a HA-coated prosthesis. Their mean age was 48 (15-79) years. During the follow-up, 12 patients died. 19 other patients did not attend the follow-up examination, but had no major symptoms according to telephone interviews and written replies. Thus, 245 patients (291 hips) were followed for a mean of 10 (8-12) years with radiographic and clinical examinations. Only 1 stem was revised due to mechanical failure. None were revised because of infection. Osteolysis was significantly associated with wear, and wear was significantly associated with the size of the femoral head. We found a small amount of proximal bone loss (37/291) and a low incidence of distal hypertrophy of the bone (23/291). These observations indicate an essentially physiological weight distribution from the stem to the femoral bone. The changes in the bone confirmed that the femoral component was well fixed in asymptomatic patients. To conclude, we found excellent 8-12-year results with a fully HA-coated femoral prosthesis designed for press-fit insertion. PMID:12807319

  14. Time trends in socioeconomic inequalities in cancer mortality: results from a 35 year prospective study in British men

    PubMed Central

    2014-01-01

    Background Socioeconomic inequalities in cancer mortality in Britain have been shown to be present in the 1990s and early 2000s. Little is known about on-going patterns in such inequalities in cancer mortality. We examined time trends in socioeconomic inequalities in cancer mortality in Britain between 1978 and 2013. Methods A socially representative cohort of 7489 British men with data on longest-held occupational social class, followed up for 35 years, in whom 1484 cancer deaths occurred. Results The hazard ratio for cancer mortality for manual vs. non-manual social classes remained unchanged; among men aged 50–59 years it was 1.62 (95%CI 1.17–2.24) between 1980–1990 and 1.65 (95%CI 1.14–2.40) between 1990–2000. The absolute difference (non-manual minus manual) in probability of surviving death from cancer to 70 years remained at 3% over the follow-up. The consistency of risks over time was similar for both smoking-related and non-smoking related cancer mortality. Conclusion Socioeconomic inequalities in cancer mortality in Britain remain unchanged over the last 35 years and need to be urgently addressed. PMID:24975430

  15. Seven-year results of a press-fit, hydroxyapatite-coated double mobility acetabular component in patients aged 65 years or older.

    PubMed

    Fresard, Pierre-Luc; Alvherne, Charles; Cartier, Jean-Loup; Cuinet, Patrick; Lantuejoul, Jean-Pierre

    2013-05-01

    One hundred and thirty-four THA were done between 1998 and 2002 with AVANTAGE(®) Press-Fit double mobility cup. The mean age of patients was 74 ± 6 years (range 65-94 years). The mean follow-up was 5.4 years (range, 0.15-10 years). The mean preoperative Harris Hip Score was 51.3 ± 14 versus 88 ± 12, at the latest follow-up, and the mean Merle d'Aubigné hip functional score was 8 ± 3 versus 16.3 ± 2.91; patients (68 %) were alive at a mean of 7.2 years postoperatively (range, 5-10 years). Three revisions were documented for aseptic loosening. The overall survival rate at 7.2 years was 96.3 % (95 % confidence interval 92.2-100) using cup revision for aseptic loosening as the end point. PMID:23412297

  16. One-year results of voluntary-based supervised exercise or treatment at orthopedic clinic for radiographic severe knee osteoarthritis

    PubMed Central

    Miyagawa, Hirofumi; Ikemoto, Tatsunori; Honjo, Hiroshi; Akao, Machiko; Tsujimoto, Toshiya; Ushida, Takahiro

    2016-01-01

    [Purpose] In this study, we investigated the efficacy of supervised physical exercise or conventional treatment on symptomatic knee osteoarthritis with severe morphological degeneration. [Subjects] Sixty-six patients with severe radiographic knee osteoarthritis were enrolled. [Methods] Participants were separated into two groups: in one group patients conducted physical exercise under supervision; while in the other group they were treated by conventional clinical methods for one year. Participants filled out two types of questionnaires; the Japanese Knee Osteoarthritis Measure and the Pain Disability Assessment Scale at baseline and one year following enrollment in the study. Two-way repeated measures analysis of variance was used to examine the effects over time and by group for a total of 43 participants; consisting of an exercise group (n=20) and a clinical group (n=23) excluding 23 dropouts. [Results] Analysis did not show a significant time-course effect or interaction between time-course and the groups in both questionnaires. On the other hand, there were significant group effects in both questionnaires with an advantage in the exercise group. [Conclusion] These results indicate that patients with knee osteoarthritis under supervised exercise conditions are more likely to maintain a better clinical outcome at one-year follow-up, despite the severe morphological degeneration in their knees. PMID:27134382

  17. Clinical results and development of heterotopic ossification in total cervical disc replacement during a 4-year follow-up

    PubMed Central

    Suchomel, Petr; Jurák, Lubomír; Brabec, Radim; Bradáč, Ondřej; Elgawhary, Shamel

    2009-01-01

    Cervical total disc replacement (CTDR) aims to decrease the incidence of adjacent segment disease through motion preservation in the operated disc space. Ongoing data collection and increasing number of studies describing heterotopic ossification (HO) resulting in decreased mobility of implants, forced us to carefully evaluate our long-term clinical and morphological results of patients with CTDR. We present the first 54 consecutive patients treated with 65 ProdiscC™ prostheses during a 12-month period (2/2004–3/2005). All patients signed an informed consent and were included in prospective long-term study approved by hospital ethical committee. The 1- and 2-year follow-up analysis were available for all patients included and 4-year results for 50 patients (60 implants). Clinical (neck disability index-NDI, visual analog scale-VAS) and radiological follow-up was conducted at 1-, 2- and 4-years after the procedure. The Mehren/Suchomel modification of McAfee scale was used to classify the appearance of HO. Mean preoperative NDI was 34.5%, VAS for neck pain intensity 4.6 and VAS for arm pain intensity 5.0. At 1-, 2- and 4-year follow-up, the mean NDI was 30.7, 27.2, and 30.4, mean VAS for neck pain intensity 2.5, 2.1 and 2.9 and mean VAS for arm pain intensity pain 2.2, 1.9 and 2.3, respectively. Significant HO (grade III) was present in 45% of implants and segmental ankylosis (grade IV) in another 18% 4 years after intervention. This finding had no clinical consequences and 92% of patients would undergo the same surgery again. Our clinical results (NDI, VAS) are comparable with fusion techniques. Although, advanced non-fusion technology is used, a significant frequency of HO formation and spontaneous fusion in cervical disc replacement surgery must be anticipated during long-term follow-up. PMID:20035357

  18. Hippocampal Atrophy and Subsequent Depressive Symptoms in Older Men and Women: Results From a 10-Year Prospective Cohort

    PubMed Central

    Elbejjani, Martine; Fuhrer, Rebecca; Abrahamowicz, Michal; Mazoyer, Bernard; Crivello, Fabrice; Tzourio, Christophe; Dufouil, Carole

    2014-01-01

    Several studies have reported smaller hippocampal volume in patients with depression. However, the temporality of the association is undetermined. One hypothesis is that hippocampal atrophy might be a susceptibility factor for depression. In the present study, we assessed whether hippocampal atrophy was associated with subsequent depressive symptoms in a cohort of older French adults (n = 1,309) who were 65–80 years of age and enrolled into the study in 1999–2001 in Dijon, France. Subjects were followed for more than 10 years. Participants underwent 2 cerebral magnetic resonance imaging scans, one at baseline and one at the 4-year follow-up. We used linear mixed models to estimate the associations of hippocampal atrophy with 1) the average depressive symptom scores over follow-up (using the Center for Epidemiologic Studies-Depression scale) measured biennially over the subsequent 6 years and 2) changes in symptom scores over follow-up. In women, a 2-standard-deviation increase in annual hippocampal atrophy was associated with a 1.67-point (95% confidence interval: 0.59, 2.77) increase in the average depressive symptom score over follow-up and with a 1.97-point (95% confidence interval: 0.68, 3.24) increase in scores over the 2 subsequent years but not with later changes in symptoms. No association was detected in men. Accounting for potential selective attrition (using inverse probability weights) did not alter results. Hippocampal atrophy was associated with more subsequent depressive symptoms and with shorter-term worsening of symptoms in women. PMID:25086051

  19. Comprehensive Comparison of the 5-Year Results of All-on-4 Mandibular Implant Systems With Acrylic and Ceramic Suprastructures.

    PubMed

    Ayna, Mustafa; Gülses, Aydin; Açil, Yahya

    2015-12-01

    The objective of the present study was to evaluate the comprehensive 5-year results of fixed mandibular dentures fabricated from metal-acrylic or metal-ceramics according to the All-on-4 protocol. Twenty-seven patients who received immediately loaded All-on-4 fixed mandibular dentures in 2006 were included in the study, and they were evaluated up to 5 years after denture integration. Endpoints were chosen in accordance with the 2007 Pisa consensus and included bone resorption, the Oral Health Impact Profile (OHIP), the sulcus fluid flow rate (SFFR), and prosthodontic complications. The initial situation in both groups was largely identical. Bone loss remained under 2 mm after 5 years in all implants and showed no group difference. The SFFR showed a gradual increase in both groups, and acrylic-bearing implants showed a substantially and significantly higher flow rate from the third year onward. The subjective improvement as expressed by the OHIP score was immediate and dramatic, and it showed no group differences. All acrylic restorations showed some extent of abrasion, and veneer fractures occurred in 4 patients (28.6%). Besides a single fracture of a fixation screw, there were no prosthetic complications in patients with ceramic suprastructures. According to bone loss and subjective outcome, acrylic and ceramic suprastructures appeared to be equivalent after 5 years; however, sulcus flow and prosthodontic complications suggest that the economic advantage of acrylic dentures may be specious. The rational choice of implant suprastructures requires comprehensive, long-term observation. Short-term economic benefits might be cancelled out in the long term. PMID:24712706

  20. Recovery potential of a western lowland gorilla population following a major Ebola outbreak: results from a ten year study.

    PubMed

    Genton, Céline; Cristescu, Romane; Gatti, Sylvain; Levréro, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sébastien; Ménard, Nelly

    2012-01-01

    Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla

  1. Intensive Weight Loss Intervention in Individuals Ages 65 Years or Older: Results from the Look AHEAD Type 2 Diabetes Trial

    PubMed Central

    Espeland, Mark A.; Rejeski, W. Jack; West, Delia S.; Bray, George A.; Clark, Jeanne M.; Peters, Anne L.; Chen, Haiying; Johnson, Karen C.; Horton, Edward S.; Hazuda, Helen P.

    2013-01-01

    OBJECTIVES To compare the relative effects of four years of intensive lifestyle intervention on weight, fitness, and cardiovascular disease risk factors among older versus younger individuals DESIGN A randomized controlled clinical trial SETTING 16 US clinical sites PARTICIPANTS Individuals with type 2 diabetes: 1,053 aged 65–76 years and 4,092 aged 45–64 years INTERVENTIONS An intensive behavioral intervention designed to promote and maintain weight loss through caloric restriction and increased physical activity compared to a condition of diabetes support and education. MEASUREMENTS Standardized assessments of weight, fitness (based on graded exercise testing), and cardiovascular disease risk factors RESULTS Across four years, older individuals had greater intervention-related mean weight losses than younger participants, 6.2% versus 5.1% (interaction p=0.006) and comparable relative mean increases in fitness, 0.56 versus 0.53 metabolic equivalents (interaction p=0.72). These benefits were seen consistently across subgroups of older adults formed by many demographic and health factors. Among a panel of age-related health conditions, only self-reported worsening vision was associated with poorer intervention-related weight loss in older individuals. The intensive lifestyle intervention produced mean increases in high density lipoprotein cholesterol (2.03 mg/dl; p<0.001) and decreases in glycated hemoglobin (0.21%; p<0.001) and waist girth (3.52 cc; p<0.001) across 4 years that were at least as large in older compared to younger individuals. CONCLUSION Intensive lifestyle intervention targeting weight loss and increased physical activity is effective in overweight and obese older individuals to produce sustained weight loss and improvements in fitness and cardiovascular risk factors. PMID:23668423

  2. Recovery Potential of a Western Lowland Gorilla Population following a Major Ebola Outbreak: Results from a Ten Year Study

    PubMed Central

    Gatti, Sylvain; Levréro, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sébastien; Ménard, Nelly

    2012-01-01

    Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla

  3. Lumbar disc replacement: preliminary results with ProDisc II after a minimum follow-up period of 1 year.

    PubMed

    Tropiano, Patrick; Huang, Russel C; Girardi, Federico P; Marnay, Thierry

    2003-08-01

    Total disc replacement has the potential to replace fusion as the gold standard surgical treatment of degenerative disc disease. Potential advantages of disc replacement over fusion include avoidance of pseudarthrosis, postoperative orthoses, and junctional degeneration. After observing satisfactory clinical results at 7-11 years' follow-up with the ProDisc first-generation implant, a second-generation prosthesis was designed. This study is a prospective analysis of the early results of total disc replacement with the ProDisc II total disc prosthesis. Fifty-three patients had single-level or multilevel disc replacement and were evaluated clinically and radiographically preoperatively and at mean 1.4-year follow-up. There were clinically and statistically significant improvements in back and leg pain Visual Analog Scale and Oswestry disability scores that were maintained at final follow-up. The clinical results of patients with single- and multilevel surgery were equivalent. Satisfactory results were achieved in 90% of patients who had previous lumbar surgery. Complications occurred in 9% of patients and included vertebral body fracture, transient radicular pain, implant malposition, and transient retrograde ejaculation. Three patients (6%) required reoperation to address complications. No mechanical failure of the implants or loosening was observed, and the prostheses retained motion. Randomized, prospective, long-term studies will be necessary to compare the effectiveness of arthrodesis with total disc replacement. PMID:12902952

  4. IceCube results from point-like source searches using 6 years of through-going muon data

    NASA Astrophysics Data System (ADS)

    Coenders, Stefan

    2016-04-01

    The IceCube Neutrino Observatory located at the geographic South Pole was designed to study and discover high energy neutrinos coming from both galactic and extra-galactic astrophysical sources. Track-like events induced by charged-current muon-neutrino interactions close to the IceCube detector give an angular resolution better than 1∘ above TeV energies. We present here the results of searches for point-like astrophysical neutrino sources on the full sky using 6 years of detector livetime, of which three years use the complete IceCube detector. Within 2000 days of detector livetime, IceCube is sensitive to a steady flux substantially below E2∂ϕ/∂E = 10-12 TeV cm-2 s-1 in the northern sky for neutrino energies above 10 TeV.

  5. A review of the practices and results of the UTMB to South Pole teledermatology program over the past six years.

    PubMed

    Sun, Angel; Lanier, Russell; Diven, Dayna

    2010-01-01

    There is no place on earth more remote and inaccessible than Antarctica. In 2002, Raytheon Polar Services Co. (RPS) awarded The University of Texas Medical Branch (UTMB) at Galveston the contract to provide specialty medical services via telemedicine to the approximately 3,500 National Science Foundation (NSF) researchers and support personnel who rotate through Antarctica in a given year. We present the practices and results of the UTMB to the South Pole teledermatology program over the past six years, from 2003 to 2008. Issues encountered include logistics of sending out biopsies for pathologic diagnosis, limited bandwidth, and satellite availability for data transmission. The UTMB to the South Pole teledermatology program demonstrates the clinical practicality of telemedicine in providing dermatologic care to remote populations in extreme climate conditions. PMID:20137758

  6. [Nine-Year Experience after ISO 15189 Acquisition, How Successful was It? Focusing on the Results of Interviews and Questionnaires].

    PubMed

    Fujimoto, Kazumitsu; Asai, Noriaki; Nakajima, Yoshinaga; Inoue, Kaoru

    2015-11-01

    Our laboratory, for the purpose of Quality Management System (QMS) improvement, acquired ISO 15189:2003 accreditation 9 years ago and completed the renewal to ISO 15189:2012 last year. In this study, we reviewed the efficacy of ISO 15189 based on an analysis of laboratory director's and managers' opinions. We could realize QMS improvement through the proactive implementation of preventive and corrective actions, and also the continuous implementation of education and delivery by means of reviewing the interview records of ISO 15189:2012 renewal with the laboratory director. All answers to the questionnaire obtained from managers with regard to the advantages of ISO 15189 acquisition agreed with the purpose of ISO 15189. From these results, we concluded that ISO 15189 acquisition was successful for QMS improvement. [Review]. PMID:26995873

  7. Impacts of climate change on Middle Eastern societies over the last 2700 years: new results from the Gejkar speleothem, Iraq

    NASA Astrophysics Data System (ADS)

    Flohr, Pascal; Fleitmann, Dominik; Bosomworth, Matt; Cheng, Hai; Sadekov, Aleksey; Matthews, Roger; Matthews, Wendy; Black, Stuart; Edwards, Lawrence

    2016-04-01

    Climatic and environmental changes are often cited as a major factor for past social, economic, and political changes. This is especially relevant in the semi-arid to arid Middle East, where, however, only few precisely dated, high-resolution climate records are available. Here we present new results from an up to annually resolved stalagmite from Gejkar Cave in the Kurdish Regional Government of Iraq region. Based on Uranium-series dating and annual layer counts, the record dates back ~2700 years, and its annual layer thickness and carbon and oxygen isotope profile appear indicative of precipitation and effective moisture. We also assess if observed decadal to multi-decadal shifts in precipitation are synchronous with socio-economic changes as observed in the archaeological and historical record in the wider Middle East over the last 2000 years, such as the largely prosperous Roman and Byzantine periods, the Seljuq invasion, and the decline of the Ottoman Empire.

  8. Aging of Polyurethane Foam Insulation in Simulated Refrigerator Panels--Three-Year Results with Third-Generation Blowing Agents

    SciTech Connect

    Wilkes, K.E.

    2001-05-29

    Laboratory data are presented on the effect of constant-temperature aging on the apparent thermal conductivity of polyurethane foam insulation for refrigerators and freezers. The foam specimens were blown with HCFC-141b and with three of its potential replacements--HFC-134a, HFC-245fa, and cyclopentane. Specimens were aged at constant temperatures of 90 F, 40 F, and -10 F. Thermal conductivity measurements were made on two types of specimens: full-thickness simulated refrigerator panels containing foam enclosed between solid plastic sheets, and thin slices of core foam cut from similar panels. Results are presented for the first three years of a multi-year aging study. Preliminary comparisons of measured data with predictions of a mathematical aging model are presented.

  9. Treatment of focal degenerative cartilage defects with polymer-based autologous chondrocyte grafts: four-year clinical results

    PubMed Central

    Kreuz, Peter C; Müller, Sebastian; Ossendorf, Christian; Kaps, Christian; Erggelet, Christoph

    2009-01-01

    Introduction Second-generation autologous chondrocyte implantation with scaffolds stabilizing the grafts is a clinically effective procedure for cartilage repair. In this ongoing prospective observational case report study, we evaluated the effectiveness of BioSeed®-C, a cell-based cartilage graft based on autologous chondrocytes embedded in fibrin and a stable resorbable polymer scaffold, for the treatment of clinical symptomatic focal degenerative defects of the knee. Methods Clinical outcome after 4-year clinical follow-up was assessed in 19 patients with preoperatively radiologically confirmed osteoarthritis and a Kellgren-Lawrence score of 2 or more. Clinical scoring was performed before implantation of the graft and 6, 12, and 48 months after implantation using the Lysholm score, the Knee injury and Osteoarthritis Outcome Score (KOOS), the International Knee Documentation Committee (IKDC) score, and the International Cartilage Repair Society (ICRS) score. Cartilage regeneration and articular resurfacing were assessed by magnetic resonance imaging (MRI) 4 years after implantation of the autologous cartilage graft. Results Significant improvement (P < 0.05) of the Lysholm and ICRS scores was observed as early as 6 months after implantation of BioSeed®-C and remained stable during follow-up. The IKDC score showed significant improvement compared with the preoperative situation at 12 and 48 months (P < 0.05). The KOOS showed significant improvement in the subclasses pain, activities of daily living, and knee-related quality of life 6 months as well as 1 and 4 years after implantation of BioSeed®-C in osteoarthritic defects (P < 0.05). MRI analysis showed moderate to complete defect filling with a normal to incidentally hyperintense signal in 16 out of 19 patients treated with BioSeed®-C. Two patients without improvement in the clinical and MRI scores received a total knee endoprosthesis after 4 years. Conclusions The results show that the good clinical

  10. Epidemiology of the human immunodeficiency virus in Saudi Arabia; 18-year surveillance results and prevention from an Islamic perspective

    PubMed Central

    Madani, Tariq A; Al-Mazrou, Yagob Y; Al-Jeffri, Mohammad H; Al Huzaim, Naser S

    2004-01-01

    Background data on HIV epidemiology and preventive measures in Islamic countries is limited. This study describes the results of 18-year of HIV surveillance in Saudi Arabia (SA) and the preventive measures implemented from an Islamic perspective. Methods surveillance for HIV has been underway in SA since 1984. Indications for HIV testing include clinical suspicion, screening of contacts of HIV-infected patients, and routine screening of blood and organ donors, prisoners, intravenous drug users, patients with other sexually transmitted infections, and expatriates pre-employment. This is a case series descriptive study of all confirmed HIV infections diagnosed in SA from 1984 through 2001. Results a total of 6046 HIV infections were diagnosed, of which 1285 (21.3%) cases were Saudi citizens. Over the 18-year surveillance period the number of HIV infections diagnosed annually among Saudi citizens gradually increased and, over the period 1997–2001, it reached to 84 to 142 cases per year. The number of cases per 100,000 population varied widely between regions with a maximum of 74 cases and a minimum of 2 cases. The infection was most common in the age group 20–40 years (74.6%) and predominantly affected men (71.6%). The modes of transmission among Saudi citizens and expatriates, respectively, were as follows: heterosexual contact, 487 (37.9%) and 1352 (28.4%) cases; blood transfusion, 322 (25.0%) and 186 (3.9%) cases; perinatal transmission, 83 (6.5%) and 19 (0.4%) cases; homosexual contact, 32 (2.5%) and 38 (0.8%) cases; intravenous drug use, 17 (1.3%) and 33 (0.7%) cases; bisexual contact, 10 (0.8%) and 14 (0.3%) cases; unknown, 334 (26.0%) and 3119 (65.5%) cases. The number of HIV infections transmitted by blood or blood products transfusion declined to zero by year 2001 and all such infections occurred due to transfusions administered before 1986. At HIV diagnosis, 4502/6046 (74.5%) patients had no symptoms, 787 (13.0%) patients had non-AIDS defining

  11. One-year results of health-related quality of life among patients undergoing transcatheter aortic valve implantation.

    PubMed

    Krane, Markus; Deutsch, Marcus-André; Piazza, Nicolo; Muhtarova, Teodora; Elhmidi, Yacine; Mazzitelli, Domenico; Voss, Bernhard; Ruge, Hendrik; Badiu, Catalin C; Kornek, Matthias; Bleiziffer, Sabine; Lange, Rüdiger

    2012-06-15

    Recently, it has been demonstrated that transcatheter aortic valve implantation (TAVI) can result in significant improvement in patients' quality of life (QOL) in the short term. At present, however, little is known about the long-term improvements in QOL after TAVI. Thus, our aim was to prospectively assess the 1-year QOL outcome of patients undergoing TAVI. We performed a prospective analysis of 186 patients with symptomatic severe aortic valve stenosis ineligible for conventional aortic valve replacement, who underwent TAVI with either the Medtronic CoreValve or Edwards Sapien device. A total of 106 patients completed the 1-year follow-up protocol. The QOL was measured using the Medical Outcomes Study 36-item short-form health survey questionnaire at baseline and at 3 months and 1 year of follow-up. At 1 year of follow-up, significant improvements in the Medical Outcomes Study 36-item short-form health survey questionnaire scores for physical functioning (baseline 34.6 ± 2.3 vs 1 year of follow-up 45.6 ± 2.7; p <0.001), role physical (20 ± 3.0 vs 34.2 ± 4.4; p <0.001), bodily pain (59.9 ± 3 vs 70 ± 2.7; p <0.01), general health (47.3 ± 1.5 vs 55.2 ± 2.1, p <0.001), vitality (35.9 ± 2 vs 48.5 ± 2; p <0.001), and mental health (62.2 ± 2.2 vs 67.3 ± 1.8; p <0.05) were observed compared to baseline. No significant improvement could be detected for social functioning (75.4 ± 2.5 vs 76.5 ± 2.6; p = 0.79) and role emotional (61.1 ± 4.3 vs 66.5 ± 4.7; p = 0.29). At 1 year of follow-up, the various physical and mental scores were comparable to an age-matched standard population. In conclusion, the present study has demonstrated that TAVI can improve the QOL status of high-surgical risk patients with severe aortic valve stenosis that can be maintained for ≤1 year postproceduraly in survivors. Although the mental subscales improved slightly, the mental component summary score failed to reach statistical significance in our study population. PMID:22520622

  12. Comparative 5-year results of short hip total hip arthroplasty with Ti- or CoCr-neck adapters.

    PubMed

    Wittenberg, Ralf H; Steffen, Reinhard

    2015-03-01

    This prospective study investigated revision after modular short stem implantation. Results are presented for 2 different types of neck adapters (titanium and cobalt-chromium [CoCr]). Eighty-five patients with titanium adapters and 87 patients with CoCr adapters underwent follow-up examination after an average of 5.7 and 5.2 years, respectively. Mean patient age was 57 years in both groups. Indications were primary osteoarthritis (80%), cup dysplasia (14%), and other (6%). Mean Harris Hip Scores were 98 and 99 points (titanium and CoCr groups, respectively). Ninety percent and 96% of patients were very satisfied or satisfied (titanium and CoCr groups, respectively); 3% of patients in both groups were dissatisfied. Pain decreased from visual analog scale score 7 and 6 preoperatively to 0.37 and 0.15 postoperatively for the titanium and CoCr groups, respectively. No joint dislocation occurred. Six patients needed revision within the first year (2 for infection, 1 for via falsa position, and 2 for aseptic loosening in the titanium group, and 1 for aseptic loosening in the CoCr group). Nine revisions occurred due to neck adapter failure (titanium group). Primary standard stems were used in all revisions. Excluding material-related adapter failures in the titanium group, the 5-year survival rate was 94.8% (95% confidence interval [CI], 88.9-97.6 for titanium) and 99% (95% CI, 93.7-99.8 for CoCr). No radiographic signs of loosening were seen at last follow-up. Fine sclerotic lines were detected in Gruen zones 1 (17.2%) and 2 (14%), hypertrophies in zone 3 (4.3%), and periprosthetic cancellous bone compressions in zone 6 (75.8%). No adapter fractures occurred for CoCr components. The treatment and anchoring system of the short stem studied yielded good results and allowed revision using standard stems in all patients. PMID:25826630

  13. First-year results of the Global Influenza Hospital Surveillance Network: 2012–2013 Northern hemisphere influenza season

    PubMed Central

    2014-01-01

    Background The Global Influenza Hospital Surveillance Network (GIHSN) was developed to improve understanding of severe influenza infection, as represented by hospitalized cases. The GIHSN is composed of coordinating sites, mainly affiliated with health authorities, each of which supervises and compiles data from one to seven hospitals. This report describes the distribution of influenza viruses A(H1N1), A(H3N2), B/Victoria, and B/Yamagata resulting in hospitalization during 2012–2013, the network’s first year. Methods In 2012–2013, the GIHSN included 21 hospitals (five in Spain, five in France, four in the Russian Federation, and seven in Turkey). All hospitals used a reference protocol and core questionnaire to collect data, and data were consolidated at five coordinating sites. Influenza infection was confirmed by reverse-transcription polymerase chain reaction. Hospitalized patients admitted within 7 days of onset of influenza-like illness were included in the analysis. Results Of 5034 patients included with polymerase chain reaction results, 1545 (30.7%) were positive for influenza. Influenza A(H1N1), A(H3N2), and both B lineages co-circulated, although distributions varied greatly between coordinating sites and over time. All age groups were affected. A(H1N1) was the most common influenza strain isolated among hospitalized adults 18–64 years of age at four of five coordinating sites, whereas A(H3N2) and B viruses were isolated more often than A(H1N1) in adults ≥65 years of age at all five coordinating sites. A total of 16 deaths and 20 intensive care unit admissions were recorded among patients with influenza. Conclusions Influenza strains resulting in hospitalization varied greatly between coordinating sites and over time. These first-year results of the GIHSN are relevant, useful, and timely. Due to its broad regional representativeness and sustainable framework, this growing network should contribute substantially to understanding the

  14. Treatment of Visceral Aneurysm Using Multilayer Stent: Two-Year Follow-Up Results in Five Consecutive Patients

    SciTech Connect

    Balderi, Alberto Antonietti, Alberto Pedrazzini, Fulvio Sortino, Davide Vinay, Claudia Grosso, Maurizio

    2013-10-15

    Purpose: The present study was performed to analyze the midterm results (five consecutive patients, 2-year follow-up) of the endovascular management of visceral artery aneurysms using the Cardiatis Multilayer Flow Modulator (CMFM) (Cardiatis, Isnes, Belgium), a self-expandable stent. Materials and Methods: From August 2009 to January 2011, we implanted five CMFMs in five patients (all men; mean age 73 years) to treat two common hepatic artery aneurysms, one celiac trunk aneurysm, one splenic artery aneurysm, and one superior mesenteric artery aneurysm (diameter 25-81 mm). The primary end point was technical success. The secondary end point was stent patency, absence of aneurysm rupture or reperfusion, and shrinking of the sac at 6-, 12-, and 24-month follow-up using computed tomography angiography. Follow-up ranged from 24 to 48 months (mean 31.2). Results: Technical success was achieved in all patients. Complete exclusion of the aneurysm with sac shrinking was achieved in two patients. Two stents became occluded at 6- and 24-month follow-up, respectively; both patients were asymptomatic and were not retreated. One patient developed sac reperfusion due to incomplete aneurysm exclusion. Conclusion: Long-term results in a wider population are needed to validate the effectiveness of the CMFM.

  15. Bacterial profiling of Saharan dust deposition in the Atlantic Ocean using sediment trap moorings – year one results

    NASA Astrophysics Data System (ADS)

    Munday, Chris; Brummer, Geert-Jan; van der Does, Michelle; Korte, Laura; Stuut, Jan-Berend

    2015-04-01

    Large quantities of dust are transported from the Sahara Desert across the Atlantic Ocean towards the Caribbean each year, with a large portion of it deposited in the ocean. This dust brings an array of minerals, nutrients and organic matter, both living and dead. This input potentially fertilizes phytoplankton growth, with resulting knock-on effects throughout the food chain. The input of terrestrial microbial life may also have an impact on the marine microbial community. The current multi-year project consists of a transect of floating dust collectors and sub-surface sediment traps placed at 12°N across the Atlantic Ocean. Sediment traps are located 1200m and 3500m below the sea surface and all are synchronized to collect samples for a period of two weeks. The aim is to understand the links between dust input and the bacterial community and how this relates to ocean productivity and the carbon cycle. The first set of sediment trap samples were recovered using the RV Pelagia in November 2013 with promising results. Results from 7 sediment traps (three at 1200m and four at 3500m) were obtained. In general, the total mass flux decreased as distance from the source increased and the upper traps generally held more material than those at 3500m. Denaturing Gradient Gel Electrophoresis (DGGE) was used as a screening technique, revealing highly varied profiles, with the upper (1200m) traps generally showing more variation throughout the year. Several samples have been submitted for high throughput DNA sequencing which will identify the variations in these samples.

  16. Randomized Controlled Trial of Forward-Planned Intensity Modulated Radiotherapy for Early Breast Cancer: Interim Results at 2 Years

    SciTech Connect

    Barnett, Gillian C.; Wilkinson, Jennifer S.; Moody, Anne M.; Wilson, Charles B.; Twyman, Nicola; Wishart, Gordon C.; Burnet, Neil G.; Coles, Charlotte E.

    2012-02-01

    Purpose: This single-center randomized trial was designed to investigate whether intensity-modulated radiotherapy (IMRT) reduces late toxicity in patients with early-stage breast cancer. Methods and Materials: The standard tangential plans of 1,145 nonselected patients were analyzed. The patients with inhomogeneous plans were randomized to a simple method of forward-planned IMRT or standard radiotherapy (RT). The primary endpoint was serial photographic assessment of breast shrinkage. Results: At 2 years, no significant difference was found in the development of any photographically assessed breast shrinkage between the patients randomized to the interventional or control group (odds ratio, 1.51; 95% confidence interval, 0.83-1.58; p = .41). The patients in the control group were more likely to develop telangiectasia than those in the IMRT group (odds ratio, 1.68; 95% confidence interval 1.13-2.40; p = .009). Poor baseline surgical cosmesis resulted in poor overall cosmesis at 2 years after RT. In patients who had good surgical cosmesis, those randomized to IMRT were less likely to deteriorate to a moderate or poor overall cosmesis than those in the control group (odds ratio, 0.63; 95% confidence interval, 0.39-1.03, p = .061). Conclusions: IMRT can lead to a significant reduction in telangiectasia at comparatively early follow-up of only 2 years after RT completion. An important component of breast induration and shrinkage will actually result from the surgery and not from the RT. Surgical cosmesis is an important determinant of overall cosmesis and could partially mask the longer term benefits of IMRT at this early stage.

  17. Number of Physics Faculty in Two-Year Colleges: Results from the 2012 Survey of Physics in Two-Year Colleges. Focus On

    ERIC Educational Resources Information Center

    White, Susan; Chu, Raymond

    2013-01-01

    In an earlier report, ("Physics Enrollments in Two-Year Colleges," ED547610), Susan White and Raymond Chu examined physics enrollments--both the number of students and the types of classes taught--at the 1,063 two-year college campuses in the US where they believe physics is offered. This "Focus On" considers the faculty…

  18. Implementing the Common Core State Standards: Year Three Progress Report from the Great City Schools. Results from 2013-14 School Year

    ERIC Educational Resources Information Center

    Palacios, Moses; Casserly, Michael; Corcoran, Amanda; Hart, Ray; Simon, Candace; Uzzell, Renata

    2014-01-01

    Three years ago, the "Council of the Great City Schools" embarked on a multi-year initiative to help its member school districts implement the Common Core State Standards (CCSS). Part of this initiative involves annual surveys of progress urban public school districts were making in implementing the CCSS. With the support of the Bill…

  19. [Neurologic appearence of Behçet disease in 14-year old boy treated with adalimumab with good result].

    PubMed

    Iwańczak, Barbara; Reich, Adam; Kofla-Dłubacz, Anna; Kazanowska, Bernarda; Ruczka, Małgorzata

    2016-02-01

    Behçet disease is a multiorgan inflammatory vessel disorder of unknown etiology which only occasionally occurs in children. Here, we demonstrate a 14-year-old boy with Behçet disease diagnosed based on recurrent aphthous stomatitis, acneiform facial lesions, subpreputial erosions and extensive thrombosis involving sigmoid sinus, transverse sinus and right internal cervical vein. Treatment with low molecular weight heparins, systemic corticosteroids, and azathioprine only resulted in partial remission of clinical symptoms. Addition of adalimumab led to complete resolution of clinical and biochemical abnormalities and disappearance of thrombosis in central nervous system. PMID:27000816

  20. The Result of In Situ Pinning for Valgus Impacted Femoral Neck Fractures of Patients over 70 Years Old

    PubMed Central

    Kim, Yoon-Chung; Lee, Joo-Yup; Oh, Seungbae

    2014-01-01

    Purpose We aimed to evaluate the outcome of fixation with cannulated screws for valgus impacted femoral neck fractures in patients over 70 years of age. Materials and Methods We reviewed the outcome in 33 patients older than 70 years with valgus impacted femoral neck fractures who were treated with cannulated screws fixation from May 2007 to December 2010. These patients were followed for at least a year. We assessed the fixation failure rate, body mass index (BMI), bone mineral density (BMD) of proximal femur, distance between screw tip and joint, number of screws and time from fracture to operation. Results We identified six patients (18.2%) with failure. Two patients with subtrochanteric fractures through the screw insertion site and another patient with osteonecrosis were excluded from the fixation failure group. No difference was found in age, BMI, BMD of proximal femur, distance between screw tip and joint, number of screws and time from fracture to operation between failure and non-failure groups. Conclusion The failure rate of cannualted screw fixation for valgus impacted femoral neck fractures in the elderly patients was not low. Risk of failure should be considered in the management of these patients and accurate assessment for fracture type should be performed using computed tomogram and clinical evaluation.

  1. Offsite radiation doses from Hanford Operations for the years 1983 through 1987: A comparison of results calculated by two methods

    SciTech Connect

    Soldat, J.K.

    1989-10-01

    This report compares the results of the calculation of potential radiation doses to the public by two different environmental dosimetric systems for the years 1983 through 1987. Both systems project the environmental movement of radionuclides released with effluents from Hanford operations; their concentrations in air, water, and foods; the intake of radionuclides by ingestion and inhalation; and, finally, the potential radiation doses from radionuclides deposited in the body and from external sources. The first system, in use for the past decade at Hanford, calculates radiation doses in terms of 50-year cumulative dose equivalents to body organs and to the whole body, based on the methodology defined in ICRP Publication 2. This system uses a suite of three computer codes: PABLM, DACRIN, and KRONIC. In the new system, 50-year committed doses are calculated in accordance with the recommendations of the ICRP Publications 26 and 30, which were adopted by the US Department of Energy (DOE) in 1985. This new system calculates dose equivalent (DE) to individual organs and effective dose equivalent (EDE). The EDE is a risk-weighted DE that is designed to be an indicator of the potential health effects arising from the radiation dose. 16 refs., 1 fig., 38 tabs.

  2. Twenty-Seven Years of Phase III Trials for Patients with Extensive Disease Small-Cell Lung Cancer: Disappointing Results

    PubMed Central

    Oze, Isao; Hotta, Katsuyuki; Kiura, Katsuyuki; Ochi, Nobuaki; Takigawa, Nagio; Fujiwara, Yoshiro; Tabata, Masahiro; Tanimoto, Mitsune

    2009-01-01

    Background Few studies have formally assessed whether treatment outcomes have improved substantially over the years for patients with extensive disease small-cell lung cancer (ED-SCLC) enrolled in phase III trials. The objective of the current investigation was to determine the time trends in outcomes for the patients in those trials. Methods and Findings We searched for trials that were reported between January 1981 and August 2008. Phase III randomized controlled trials were eligible if they compared first-line, systemic chemotherapy for ED-SCLC. Data were evaluated by using a linear regression analysis. Results: In total, 52 trials were identified that had been initiated between 1980 and 2006; these studies involved 10,262 patients with 110 chemotherapy arms. The number of randomized patients and the proportion of patients with good performance status (PS) increased over time. Cisplatin-based regimens, especially cisplatin and etoposide (PE) regimen, have increasingly been studied, whereas cyclophosphamide, doxorubicin, and vincristine–based regimens have been less investigated. Multiple regression analysis showed no significant improvement in survival over the years. Additionally, the use of a PE regimen did not affect survival, whereas the proportion of patients with good PS and the trial design of assigning prophylactic cranial irradiation were significantly associated with favorable outcome. Conclusions and Significance The survival of patients with ED-SCLC enrolled in phase III trials did not improve significantly over the years, suggesting the need for further development of novel targets, newer agents, and comprehensive patient care. PMID:19915681

  3. Publication and non-publication of drug trial results: a 10-year cohort of trials in Norwegian general practice

    PubMed Central

    Brænd, Anja Maria; Straand, Jørund; Jakobsen, Rune Bruhn; Klovning, Atle

    2016-01-01

    Objectives Previously, we identified a 10-year cohort of protocols from applications to the Norwegian Medicines Agency 1998–2007, consisting of 196 drug trials in general practice. The aim of this study was to examine whether trial results were published and whether trial funding and conflicts of interest were reported. Design Cohort study of trials with systematic searches for published results. Setting Clinical drug trials in Norwegian general practice. Methods We performed systematic literature searches of MEDLINE, Embase and CENTRAL to identify publications originating from each trial using characteristics such as test drug, comparator and patient groups as search terms. When no publication was identified, we contacted trial sponsors for information regarding trial completion and reference to any publications. Main outcome measures We determined the frequency of publication of trial results and trial characteristics associated with publication of results. Results Of the 196 trials, 5 were never started. Of the remaining 191 trials, 71% had results published in a journal, 11% had results publicly available elsewhere and 18% of trials had no results available. Publication was more common among trials with an active comparator drug (χ2 test, p=0.040), with a larger number of patients (total sample size≥median, p=0.010) and with a longer trial period (duration≥median, p=0.025). Trial funding was reported in 85% of publications and increased over time, as did reporting of conflicts of interest among authors. Among the 134 main journal articles from the trials, 60% presented statistically significant results for the investigational drug, and the conclusion of the article was favourable towards the test drug in 78% of papers. Conclusions We did not identify any journal publication of results for 29% of the general practice drug trials. Trials with an active comparator, larger and longer trials were more likely to be published. PMID:27067893

  4. Replacement of Vertebral Lamina (Laminoplasty) in Surgery for Lumbar Isthmic Spondylolisthesis: 5-Year Follow-Up Results

    PubMed Central

    2016-01-01

    Study Design A review of clinical and radiological outcomes of lumbar laminoplasty (LL) for the treatment of isthmic spondylolisthesis (ISL). Purpose The single session performance of posterior lumbar interbody fusion with allograft in the anterior column and providing the realignment of the vertebrae was presented as a preliminary report earlier. Overview of Literature Long-term surgical outcome of cervical laminoplasty in patients has been reported. But, outcome of LL in patients is unclear. Methods The long-term (5 years) year follow-up results of the LL technique are reported in this retrospective study. All patients underwent preoperative and postoperative direct X-ray, computed tomography, and magnetic resonance imaging. The patients that did not respond to conservative treatment were operated. Twenty-one (52.5%) female and 19 (47.5%) male patients were included. Results Mean age was 43,5 years (ranges, 22–57 years). The most common symptoms were low back pain (89%), pelvic and leg pain (69%) and reduction in walking distance (65%). A total of 180 pedicle screws were inserted in 40 patients; posterior lumbar interbody fusion and laminoplasty with reduction was performed in 20 patients for L4–L5, 12 patients for L5–S1, 4 patients for L3–L4–L5 and 4 patients for L4–L5-S1. Ten (25%) patients with ILL had accompanying spinal stenosis. The difference between preoperative and postoperative sagittal plane rotation and dislocation degrees and disc space heights were statistically significant in all patients (p<0.05). Solid grade 4 fusion was observed in 38 patients; in only 2 patients grade 2 pseudoarthrosis developed (5%), but these patients were asymptomatic. Visual analog scale, Prolo economical and functional scale was examined with an average follow-up 5.5 years. Conclusions LL technique has the advantages of shorter duration of operation, lack of graft donor site complications, protection of posterior column osseoligamentous structures and

  5. Prone Accelerated Partial Breast Irradiation After Breast-Conserving Surgery: Five-year Results of 100 Patients

    SciTech Connect

    Formenti, Silvia C.; Hsu, Howard; Fenton-Kerimian, Maria; Roses, Daniel; Guth, Amber; Jozsef, Gabor; Goldberg, Judith D.; DeWyngaert, J. Keith

    2012-11-01

    Purpose: To report the 5-year results of a prospective trial of three-dimensional conformal external beam radiotherapy (3D-CRT) to deliver accelerated partial breast irradiation in the prone position. Methods and Materials: Postmenopausal patients with Stage I breast cancer with nonpalpable tumors <2 cm, negative margins and negative nodes, positive hormone receptors, and no extensive intraductal component were eligible. The trial was offered only after eligible patients had refused to undergo standard whole-breast radiotherapy. Patients were simulated and treated on a dedicated table for prone setup. 3D-CRT was delivered at a dose of 30 Gy in five 6-Gy/day fractions over 10 days with port film verification at each treatment. Rates of ipsilateral breast failure, ipsilateral nodal failure, contralateral breast failure, and distant failure were estimated using the cumulative incidence method. Rates of disease-free, overall, and cancer-specific survival were recorded. Results: One hundred patients were enrolled in this institutional review board-approved prospective trial, one with bilateral breast cancer. One patient withdrew consent after simulation, and another patient elected to interrupt radiotherapy after receiving two treatments. Ninety-eight patients were evaluable for toxicity, and, in 1 case, both breasts were treated with partial breast irradiation. Median patient age was 68 years (range, 53-88 years); in 55% of patients the tumor size was <1 cm. All patients had hormone receptor-positive cancers: 87% of patients underwent adjuvant antihormone therapy. At a median follow-up of 64 months (range, 2-125 months), there was one local recurrence (1% ipsilateral breast failure) and one contralateral breast cancer (1% contralateral breast failure). There were no deaths due to breast cancer by 5 years. Grade 3 late toxicities occurred in 2 patients (one breast edema, one transient breast pain). Cosmesis was rated good/excellent in 89% of patients with at least 36

  6. Risk factors for late-onset generalized anxiety disorder: results from a 12-year prospective cohort (the ESPRIT study).

    PubMed

    Zhang, X; Norton, J; Carrière, I; Ritchie, K; Chaudieu, I; Ancelin, M-L

    2015-01-01

    Generalized anxiety disorder (GAD) is a chronic and highly prevalent disorder associated with increased disability and mortality in the elderly. Treatment is difficult with low rate of full remission, thus highlighting the need to identify early predictors for prevention in elderly people. The aim of this study is to identify and characterize incident GAD predictors in elderly people. A total of 1711 individuals aged 65 years and above and free of GAD at baseline were randomly recruited from electoral rolls between 1999 and 2001 (the prospective ESPRIT study). The participants were examined at baseline and five times over 12 years. GAD and psychiatric comorbidity were diagnosed with a standardized psychiatric examination, the Mini-International Neuropsychiatry Interview on the basis of DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth edition) criteria and validated by a clinical panel. During the follow-up, 8.4% (95% confidence interval=7.1-9.7%) of the participants experienced incident GAD, 80% being first episodes; the incident rate being 10 per 1000 person-years. The principal predictors of late-onset incident GAD over 12 years derived from a multivariate Cox model were being female, recent adverse life events, having chronic physical (respiratory disorders, arrhythmia and heart failure, dyslipidemia, cognitive impairment) and mental (depression, phobia and past GAD) health disorders. Poverty, parental loss or separation and low affective support during childhood, as well as history of mental problems in parents were also significantly and independently associated with incident GAD. GAD appears as a multifactorial stress-related affective disorder resulting from both proximal and distal risk factors, some of them being potentially modifiable by health care intervention. PMID:25826111

  7. Determination of Effective Factors on Survival of GI Cancers: Results of Five Years Follow up in Iranian Population

    PubMed Central

    Zargar, Ali; Miroliaee, Arash; Gooraji, Somayeh Ahmadi; Hajaghamohammadi, Aliakbar

    2016-01-01

    Background: The gastrointestinal cancers are among the most common cause of cancer-related death and their long term survival is very low. This study was aimed to determine the effective factors on survival of gastrointestinal cancers among Iranian population during 5 years of follow up. Methods: In total, 157 patients diagnosed as gastrointestinal cancers from 2007 to 2009 in the only center of endoscopy in Alvand city, northwest of Qazvin province were included and followed for five years. The univariate and multivariate analysis were done using Kaplan-Meier method and the Cox model respectively. Results: Observations of 146 patients were analyzed (99 (67.8%) males and 47 (32.2%) females). The mean age was 64.73± 13.23 and 58.28±13.91 for females and males respectively. The one and three years survival rates for esophageal cancer were 28% and 9% and the one, three and five years survival rates for gastric cancer were 31%, 26% and 14% and for colorectal cancer were 96%, 86% and 75% respectively. In the univariate analysis, variables of age, educational level, ethnicity, smoking, type of cancer, stage of disease and type of treatment had significant effects on survival. In the multivariate analysis, the type of cancer and type of treatment affected the survival of patients as effective factors (p<005). Conclusion: Patients with esophageal cancer and those who underwent RT &/or CT are exposed to higher risk of death. Combination therapies (Surgery and adjuvant or neoadjuvant therapy) were related to be her survival. Early diagnosis and use of extended cancer screening programs seem necessary to improve survival. PMID:26755479

  8. Changes in Sexual Function in Benign Prostatic Hyperplasia Patients Taking Dutasteride: 1-Year Follow-Up Results

    PubMed Central

    Chi, Byung Hoon

    2011-01-01

    Purpose Sexual adverse events (AEs), a major cause for discontinuing 5α-reductase inhibitor (5ARI) therapy for benign prostatic hyperplasia (BPH), are known to occur most frequently early in therapy and appear to decline over time. The aim of this study was to investigate the changes in sexual function occurring with dutasteride treatment during a 1-year follow-up period in Korean men. Materials and Methods Using the International Index of Erectile Function, we prospectively evaluated, after 1, 3, 6, 9, and 12 months of treatment, the changes in sexual function of 55 outpatients (mean age 62.3±7.2 years) with BPH (mean volume 48.9±16.0 g) who had relatively good erectile function (EF) and were treated with dutasteride for at least 1 year. Results EF scores showed the most significant decrease at 1 month (p<0.01). Function gradually recovered thereafter but was still significantly decreased after 12 months of treatment (p<0.05). The scores for orgasmic function and sexual desire also showed the most significant reduction at 1 month but were restored to the baseline level at 6 months. No significant correlation was observed between changes in sexual function and prostate-specific antigen level, prostate volume, or International Prostate Symptom Scores. Conclusions After 1 month of treatment, dutasteride therapy resulted in a significant reduction in all investigated sexual functions. Overall, recovery in sexual function was noted at 3 months, and orgasmic function and sexual desire were restored to baseline levels at 6 months. However, EF was still significantly reduced at 12 months. PMID:22025960

  9. Results of a unicentric series of 15 wrist prosthesis implantations at a 5.2 year follow-up.

    PubMed

    Chevrollier, Jérémie; Strugarek-Lecoanet, Clotilde; Dap, François; Dautel, Gilles

    2016-03-01

    Our retrospective study aimed to evaluate functional and radiological results of a unicentric series of 17 total wrist prostheses implanted between 2001 and 2011. Nine women and seven men, mean age 59, underwent wrist joint arthroplasty, bilateral in one case. Universal Total Wrist and Remotion prostheses were used and followed-up at a mean of 5.2 years (1.1-10). Fifteen patients were reviewed. Four patients had postoperative complications, three of whom required arthrodesis. The rest obtained satisfactory pain relief. Grip strength nevertheless decreased compared to the contralateral side and mobility was reduced: flexion/extension=33°, ulnar/radial deviation=20°. The Quick DASH score was 29% and PRWE, 26%. Radiological assessment revealed carpal implant loosening in eight patients. Our series confirms the discordance generally observed between patients' subjective satisfaction and mediocre clinical and radiological results over the medium term. PMID:26984652

  10. Possible Niches For Extant Life On Titan In Light Of The First Six Years Of Cassini/Huygens Results

    NASA Astrophysics Data System (ADS)

    Grinspoon, David H.; Schulze-Makuch, D.

    2010-10-01

    At the 2005 DPS meeting we presented an assessment of the possibility of extant life on Titan after the first year of the Cassini mission at Saturn. We suggested then that hydrogenation of photochemically produced acetylene could provide metabolic energy for near-surface organisms and also replenish atmospheric methane (Schulze-Makuch and Grinspoon, 2005). In this talk we will offer a brief reassessment of the possibility of extant life in light of five more years of the Cassini/Huygens results, including the recent reports suggesting a lack of acetylene on the surface (Clark et al., 2010) and a possible sink of H2 at the surface (Strobel, 2010). Both results are consistent with earlier predictions for the existence of an acetylene-powered biosphere on Titan (Schulze-Makuch and Grinspoon, 2005; McKay and Smith, 2005), but can potentially be explained by more prosaic phenomena. D. Schulze-Makuch and D. H. Grinspoon(2005), Biologically Enhanced Energy and Carbon Cycling on Titan? Astrobiology 5, 560-567; Clarke, R.N. et al. (2020), Detection and Mapping of Hydrocarbon Deposits on Titan, JGR-Planets; Strobel, D.F(2010) Molecular hydrogen in Titan's atmosphere: Implications of the measured tropospheric and thermospheric mole fractions. Icarus; McKay, C.P., Smith, H.D.( 2005) Possibilities for methanogenic life in liquid methane on the surface of Titan. Icarus 178, 274-276.

  11. Results from a model of course-based undergraduate research in the first- and second-year chemistry curriculum

    NASA Astrophysics Data System (ADS)

    Weaver, Gabriela

    2014-03-01

    The Center for Authentic Science Practice in Education (CASPiE) is a project funded by the URC program of the NSF Chemistry Division. The purpose of CASPiE was to provide students in first and second year laboratory courses with authentic research experiences as a gateway to more traditional forms of undergraduate research. Each research experience is a 6- to 8-week laboratory project based on and contributing to the research work of the experiment's author through data or preparation of samples. The CASPiE program has resulted in a model for engaging students in undergraduate research early in their college careers. To date, CASPiE has provided that experience to over 6000 students at 17 different institutions. Evaluation data collected has included student surveys, interviews and longitudinal analysis of performance. We have found that students' perceptions of their understanding of the material and the discipline increase over the course of the semester, whereas they are seen to decrease in the control courses. Students demonstrate a greater ability to explain the meaning and purpose of their experimental procedures and results and provide extensions to the experimental design, compared not only to control courses but also compared to inquiry-based courses. Longitudinal analysis of grades indicates a possible benefit to performance in courses related to the discipline two and three years later. A similar implementation in biology courses has demonstrated an increase in critical thinking scores. Work supported by the National Science Foundation, Division of Chemistry.

  12. A Prospective Study of Early Loaded Single Implant-Retained Mandibular Overdentures: Preliminary One-Year Results

    PubMed Central

    El-Sheikh, Ali M.; Shihabuddin, Omar F.; Ghoraba, Sahar M. F.

    2012-01-01

    Purpose. To investigate the predictability of simplifying mandibular overdenture treatment using one-stage surgery and early prosthetic loading of a single implant. Materials and Methods. Twenty edentulous patients with problematic existing mandibular dentures were treated. A single implant with a chemically modified surface (SLActive, Straumann AG, Basel, Switzerland) was placed into the mandibular midline. The patients were recalled at 3, 6 and 12 months. Clinical assessments and marginal bone loss using standardized radiographs were recorded. All complications, failures and maintenance were noted. Visual analog-scale questionnaires were used to record patient satisfaction in five categories. ANOVA was used to determine differences between means of marginal bone loss and different categories of patient staisfaction (P = 0.05). Results. The 20 early loaded implants were all surviving at the 12-month recall. All implants showed less than 1 mm of marginal bone loss by the end of the 1-year with a significant increase during the follow-up period. Few prosthetic problems were reported. Patient satisfaction was high with a significant increase in all comfort and functional parameters. Conclusions. These preliminary 1-year results indicate that early loading of a single chemically modified surface implant used to retain a mucosa-borne mandibular overdenture is a safe, reliable, and cost-effective treatment. PMID:22505895

  13. [Results of esophagogastroduodenoscopy many years after Chernobyl accident among those taking place in the liquidation of the results of the disaster].

    PubMed

    Kharchenko, V P; Sinev, Iu V; Ivanova, O V

    2002-01-01

    Gastroduodenal disorders were studied endoscopically for 5 years in 159 Chernobyl wreckers and were compared to subjects unexposed to ionising radiation. Upper gastroduodenal tract was examined with esophagogastroduodenoscopy to avoid additional radiation load. It was found that 8-12 years after irradiation, many examinees had gastroduodenal mucosa erosions the rate of which was persistently high. Incidences of malignant and benign tumors in the study and control groups did not differ significantly. PMID:12138798

  14. Diet in 1-year-old farm and control children and allergy development: results from the FARMFLORA birth cohort

    PubMed Central

    Jonsson, Karin; Green, My; Barman, Malin; Sjöberg, Agneta; Brekke, Hilde K.; Wold, Agnes E.; Sandberg, Ann-Sofie

    2016-01-01

    Background A farming environment confers strong protection against allergy development. We have previously shown that farming mothers consume more full-fat dairy than control mothers, who instead consume more low-fat dairy, margarine, and oils; margarine and oil intake was associated with increased risk of allergy development in their children. Objectives The aims of this study were to investigate the differences in diet between children in farming and control families at 1 year of age, to investigate the relation between the diets of the mothers and their children, and to relate the children's diet to allergy development. Design The diet of 1-year-old children from dairy farming families (n=28) and from control families in the same rural area (n=37) was assessed by 24-h dietary recalls, followed by 24-h food diaries. Allergy was diagnosed by pediatricians at 3 years of age using strict predefined criteria. Results Farm children had a higher intake of farm milk, whole cream, cholesterol, saturated fat, and fat in total and tended to eat more butter, while controls consumed more carbohydrates and poultry and tended to eat more margarine. Farm children also had higher intakes of homemade porridge/gruel, oily fish, and iodine. The intake of butter and whole milk in children and mothers correlated significantly in farm families but not in controls. A weak negative association was found between seafood intake and allergy development, while allergy was positively associated with the intake of pork as well as zinc in the control group; these intakes also correlated with each other. Conclusions Consistent with mothers in farming families, the children consumed more full-fat dairy and saturated fat than did controls, but this could not be linked to the low risk of allergy in the farming group. Seafood intake might protect against allergy development, in accordance with earlier findings. PMID:27534847

  15. High-Dose-Rate Rotte 'Y' Applicator Brachytherapy for Definitive Treatment of Medically Inoperable Endometrial Cancer: 10-Year Results

    SciTech Connect

    Coon, Devin; Beriwal, Sushil Heron, Dwight E.; Kelley, Joseph L.; Edwards, Robert P.; Sukumvanich, Paniti; Zorn, Kristin K.; Krivak, Thomas C.

    2008-07-01

    Purpose: To assess the intermediate clinical outcomes of medically inoperable patients with endometrial cancer treated with definitive Rotte 'Y' applicator high-dose-rate brachytherapy (HDRB) over a 10-year period. Methods and Materials: Forty-nine inoperable patients were treated with HDRB from 1997 to 2007. Forty three (84%) were markedly obese (body mass index >35 kg/m{sup 2}). Thirty-one patients (63.3%) underwent two-dimensional treatment planning, whereas 18 patients (36.7%) underwent three-dimensional treatment planning. Thirty five of the patients (71.4%) were first treated with external beam radiotherapy (EBRT). For patients receiving EBRT in addition to HDRB, the median Y-applicator dose was 20 Gy in 5 fractions; for patients receiving HDRB alone it was 35 Gy in 5 fractions. All patients received two Y-applicator treatments per day. Results: Median follow-up time for all patients was 33 months. Acute HDRB toxicities were limited to Grade 1 and 2 occurring in 5 patients. One patient had a myocardial infarction. Four patients had late Grade 2 or 3 toxicity. Three patients had local recurrence (median time to recurrence, 16 months). The 3- and 5-year actuarial cause-specific survival rates were 93% and 87%, respectively; the overall survival rate was 83% and 42%, respectively, at 3 and 5 years. Conclusions: Twice-daily HDRB using a Y-applicator is a well-tolerated and efficacious regimen for the definitive treatment of medically inoperable patients with early-stage endometrial cancer. The recent incorporation of three-dimensional treatment planning has the potential to further decrease treatment morbidities.

  16. Nitinol stent implantation for femoropopliteal disease in patients on hemodialysis: results of the 3-year retrospective multicenter APOLLON study.

    PubMed

    Fujihara, Masahiko; Higashimori, Akihiro; Kato, Yoshihiro; Taniguchi, Hiromasa; Iwasaki, Yusuke; Amano, Tomonori; Sumiyoshi, Akinori; Nishiya, Daisuke; Yokoi, Yoshiaki

    2016-09-01

    The clinical outcomes of nitinol stents for femoropopliteal arterial (FP) disease in patients on hemodialysis were assessed. Endovascular therapy (EVT) is accepted for symptomatic FP disease. However, the clinical outcomes of patients on dialysis are not well known. A multicenter retrospective study was conducted with data between November 2010 and August 2013. A total of 484 consecutive patients who successfully underwent EVT for FP disease with nitinol stents were recruited and analyzed. Patients were categorized into the hemodialysis group (N = 161) and non-hemodialysis group (N = 323). The primary measure was primary patency verified by duplex ultrasound at a rest peak systolic velocity (PSVR) of >2.5, and secondary measures were freedom from target lesion revascularization (TLR) and major amputation-free survival (AFS). Average follow-up duration was 19.5 ± 13.5 months. The primary patency rate at 3 years was significantly lower in the hemodialysis group than the non-hemodialysis group (33.8 vs. 43.7 %; p = 0.036). Freedom from TLR at 3 years was 55.0 % in the hemodialysis group and 66.1 % in the non-hemodialysis group (p = 0.032). The hemodialysis group showed a significantly lower AFS rate at 3 years than the non-hemodialysis group (86.4 vs. 58.2 %; p < 0.001). In hemodialysis patients, nitinol stent use resulted in a lower patency rate, higher TLR rate, and lower AFS rate compared to non-hemodialysis patients. These data suggest that nitinol stent implantation for FP arteries in hemodialysis patient needs to be reconsidered. PMID:26337619

  17. Five-year results of a randomised controlled trial comparing mobile and fixed bearings in total knee replacement.

    PubMed

    Breeman, S; Campbell, M K; Dakin, H; Fiddian, N; Fitzpatrick, R; Grant, A; Gray, A; Johnston, L; MacLennan, G S; Morris, R W; Murray, D W

    2013-04-01

    There is conflicting evidence about the merits of mobile bearings in total knee replacement, partly because most randomised controlled trials (RCTs) have not been adequately powered. We report the results of a multicentre RCT of mobile versus fixed bearings. This was part of the knee arthroplasty trial (KAT), where 539 patients were randomly allocated to mobile or fixed bearings and analysed on an intention-to-treat basis. The primary outcome measure was the Oxford Knee Score (OKS) plus secondary measures including Short Form-12, EuroQol EQ-5D, costs, cost-effectiveness and need for further surgery. There was no significant difference between the groups pre-operatively: mean OKS was 17.18 (sd 7.60) in the mobile-bearing group and 16.49 (sd 7.40) in the fixed-bearing group. At five years mean OKS was 33.19 (sd 16.68) and 33.65 (sd 9.68), respectively. There was no significant difference between trial groups in OKS at five years (-1.12 (95% confidence interval -2.77 to 0.52) or any of the other outcome measures. Furthermore, there was no significant difference in the proportion of patients with knee-related re-operations or in total costs. In this appropriately powered RCT, over the first five years after total knee replacement functional outcomes, re-operation rates and healthcare costs appear to be the same irrespective of whether a mobile or fixed bearing is used. PMID:23539700

  18. Golimumab administered subcutaneously every 4 weeks in ankylosing spondylitis: 5-year results of the GO-RAISE study

    PubMed Central

    Deodhar, Atul; Braun, Jürgen; Inman, Robert D; Zhou, Yiying; Xu, Stephen; Han, Chenglong; Hsu, Benjamin

    2015-01-01

    Objective Assess golimumab efficacy/safety through 5 years in patients with active ankylosing spondylitis (AS). Methods 356 patients with AS were randomly assigned to placebo, golimumab 50 mg or 100 mg every 4 weeks. At week 16, patients with inadequate response early escaped with blinded dose adjustments (placebo to 50 mg, 50 mg to 100 mg). At week 24, all patients receiving placebo crossed over to 50 mg. Blinded active therapy continued through week 104; from week 104 to week 252, the golimumab dose could be adjusted. Intent-to-treat and observed efficacy data were assessed by randomised treatment groups. Results At week 256, and with >4.5 years of golimumab, overall intent-to-treat Assessment in SpondyloArthritis international Society criteria for 20% improvement (ASAS20) and ASAS40 response rates were 66.0% (235/356) and 57.0% (203/356), respectively; Bath AS Disease Activity Index 50% improvement response was 55.9% (199/356). Observed response rates among the 255 (72%) patients who continued golimumab through week 252 were consistent, albeit somewhat higher. Among patients who increased golimumab from 50 to 100 mg, 60.6% (20/33) and 44.7% (17/38) achieved ASAS20/ASAS40 responses, respectively, following ≥2 consecutive doses of golimumab 100 mg. Golimumab safety through week 268 was similar to that through week 24 regardless of dose. Conclusions Clinical improvements observed in patients treated with golimumab through week 24 were sustained through week 256 (5 years). Long-term golimumab safety is consistent with that of other established tumour-necrosis-factor-antagonists. Trial registration number ClinicalTrials.gov: NCT00265083. PMID:25387477

  19. Long term results of primary posterior chamber intraocular lens implantation for congenital cataract in the first year of life

    PubMed Central

    Gouws, P; Hussin, H M; Markham, R H C

    2006-01-01

    Aim To document the long term outcome of congenital cataract surgery with primary posterior chamber (PC) lens implantation in the first year of life. Method A retrospective review of congenital cataract surgery in the first year of life with PC lens implantation in 18 infants, eight with unilateral and 10 with bilateral cataract. The average age at surgery was 15 weeks (range 3–44 weeks). The mean follow up was 95 months (range 60–139 months). Results The best outcomes were in the bilateral group where 50% of eyes achieved 6/18 or better, with a best acuity of 6/9. Acuities were poor in the unilateral group where only 38% achieved 6/60 or better, with a best acuity of 6/24. There was a mean refractive shift between first refraction after surgery and refraction at 36 months after surgery of −3.44 dioptres with a very wide range (+2.00 to −15.50). There was a significantly greater myopic shift in the unilateral cases. Many eyes in both groups continued to show an increasing myopic shift between 36 months after surgery and their final recorded refraction. The main complications were amblyopia, especially in unilateral cataracts, and posterior capsular opacification. Amblyopia was most probably related to a combination of early onset of dense cataract in this young age group, late presentation for initial surgery, delay in capsulotomies, and imperfect compliance with a rigorous occlusion regime. Conclusion Intraocular lens implantation in infants less than 1 year of age is generally a safe procedure. The spread of final refractive error was very wide. Final refraction in the unilateral group was significantly more myopic than the bilateral group. Final acuities were often disappointing especially in the unilateral group. PMID:16597661

  20. Effects of a Prekindergarten Educational Intervention on Adult Health: 37-Year Follow-Up Results of a Randomized Controlled Trial

    PubMed Central

    Schweinhart, Lawrence; Montie, Jeanne; Neidell, Matthew

    2009-01-01

    Objectives. We used 37 years of follow-up data from a randomized controlled trial to explore the linkage between an early educational intervention and adult health. Methods. We analyzed data from the High/Scope Perry Preschool Program (PPP), an early school-based intervention in which 123 children were randomized to a prekindergarten education group or a control group. In addition to exploring the effects of the program on health behavioral risk factors and health outcomes, we examined the extent to which educational attainment, income, family environment, and health insurance access mediated the relationship between randomization to PPP and behavioral and health outcomes. Results. The PPP led to improvements in educational attainment, health insurance, income, and family environment Improvements in these domains, in turn, lead to improvements in an array of behavioral risk factors and health (P = .01). However, despite these reductions in behavioral risk factors, participants did not exhibit any overall improvement in physical health outcomes by the age of 40 years. Conclusions. Early education reduces health behavioral risk factors by enhancing educational attainment, health insurance coverage, income, and family environments. Further follow-up will be needed to determine the long-term health effects of PPP. PMID:19542034

  1. Viral Etiology of Encephalitis in Children in Southern Vietnam: Results of a One-Year Prospective Descriptive Study

    PubMed Central

    Tan, Le Van; Qui, Phan Tu; Ha, Do Quang; Hue, Nguyen Bach; Bao, Lam Quoi; Cam, Bach Van; Khanh, Truong Huu; Hien, Tran Tinh; Vinh Chau, Nguyen Van; Tram, Tran Tan; Hien, Vo Minh; Nga, Tran Vu Thieu; Schultsz, Constance; Farrar, Jeremy; van Doorn, H. Rogier; de Jong, Menno D.

    2010-01-01

    Background Acute encephalitis is an important and severe disease in children in Vietnam. However, little is known about the etiology while such knowledge is essential for optimal prevention and treatment. To identify viral causes of encephalitis, in 2004 we conducted a one-year descriptive study at Children's Hospital Number One, a referral hospital for children in southern Vietnam including Ho Chi Minh City. Methodology/Principal Findings Children less than 16 years of age presenting with acute encephalitis of presumed viral etiology were enrolled. Diagnostic efforts included viral culture, serology and real time (RT)-PCRs. A confirmed or probable viral causative agent was established in 41% of 194 enrolled patients. The most commonly diagnosed causative agent was Japanese encephalitis virus (n = 50, 26%), followed by enteroviruses (n = 18, 9.3%), dengue virus (n = 9, 4.6%), herpes simplex virus (n = 1), cytomegalovirus (n = 1) and influenza A virus (n = 1). Fifty-seven (29%) children died acutely. Fatal outcome was independently associated with patient age and Glasgow Coma Scale (GCS) on admission. Conclusions/Significance Acute encephalitis in children in southern Vietnam is associated with high mortality. Although the etiology remains unknown in a majority of the patients, the result from the present study may be useful for future design of treatment and prevention strategies of the disease. The recognition of GCS and age as predictive factors may be helpful for clinicians in managing the patient. PMID:21049060

  2. Patterns of shoulder pain during a 14-year follow-up: results from a longitudinal population study in Norway

    PubMed Central

    Grotle, Margreth; Natvig, Bård

    2014-01-01

    Background Population studies have reported that shoulder pain is the third most frequently reported musculoskeletal pain. Long duration, pain intensity and high level of disability predict persistent complaints. The present study aimed to describe the prevalence of shoulder pain in a general population and follow this over a long period (1990 to 2004). The objective was also to describe the stability of shoulder pain and patterns of co-occurrence with neck and upper back pain. Methods Data were obtained from a self-reported questionnaire in a population in Ullensaker muncipality, north-east of Oslo. The Standard Nordic Questionnaire was sent in 1990, 1994 and 2004 to inhabitants belonging to six birth cohorts from 1918–20 to 1968–70. Results The 1-year prevalence of shoulder pain was 46.7% (95% CI, 44.9% to 48.6%) in 1990, 48.7% (95% CI, 46.8% to 50.5%) in 1994, and 55.2% (95% CI, 53.5% to 56.9%) in 2004. Approximately three-quarters of the persons with shoulder pain at one given time also reported shoulder pain at the next follow-up. Conclusions Prevalence of shoulder pain during a 14-year period was high and slightly increasing. Shoulder pain was reported most frequently in co-occurrence with neck pain. Classification models should include neck pain as well as other co-occurring pain sites.

  3. Results From the First Six Years of National Sentinel Surveillance for Influenza in Kenya, July 2007–June 2013

    PubMed Central

    Katz, Mark A.; Muthoka, Philip; Emukule, Gideon O.; Kalani, Rosalia; Njuguna, Henry; Waiboci, Lilian W.; Ahmed, Jamal A.; Bigogo, Godfrey; Feikin, Daniel R.; Njenga, Moses K.; Breiman, Robert F.; Mott, Joshua A.

    2014-01-01

    Background Recent studies have shown that influenza is associated with significant disease burden in many countries in the tropics, but until recently national surveillance for influenza was not conducted in most countries in Africa. Methods In 2007, the Kenyan Ministry of Health with technical support from the CDC-Kenya established a national sentinel surveillance system for influenza. At 11 hospitals, for every hospitalized patient with severe acute respiratory illness (SARI), and for the first three outpatients with influenza-like illness (ILI) per day, we collected both nasopharyngeal and oropharyngeal swabs. Beginning in 2008, we conducted in-hospital follow-up for SARI patients to determine outcome. Specimens were tested by real time RT-PCR for influenza A and B. Influenza A-positive specimens were subtyped for H1, H3, H5, and (beginning in May 2009) A(H1N1)pdm09. Results From July 1, 2007 through June 30, 2013, we collected specimens from 24,762 SARI and 14,013 ILI patients. For SARI and ILI case-patients, the median ages were 12 months and 16 months, respectively, and 44% and 47% were female. In all, 2,378 (9.6%) SARI cases and 2,041 (14.6%) ILI cases were positive for influenza viruses. Most influenza-associated SARI cases (58.6%) were in children <2 years old. Of all influenza-positive specimens, 78% were influenza A, 21% were influenza B, and 1% were influenza A/B coinfections. Influenza circulated in every month. In four of the six years influenza activity peaked during July–November. Of 9,419 SARI patients, 2.7% died; the median length of hospitalization was 4 days. Conclusions During six years of surveillance in Kenya, influenza was associated with nearly 10 percent of hospitalized SARI cases and one-sixth of outpatient ILI cases. Most influenza-associated SARI and ILI cases were in children <2 years old; interventions to reduce the burden of influenza, such as vaccine, could consider young children as a priority group. PMID:24955962

  4. ESEM results and changes in wettability patterns within soil: three years irrigation with slightly-salted water

    NASA Astrophysics Data System (ADS)

    Valdes-Abellan, Javier; Candela, Lucila; Medero, Gabriela; Buckman, Jim; Hasnayn, Mohammad M.

    2015-04-01

    Impacts on soil and aquifer media from the use of non-conventional water (treated wastewater-TWW, desalted) for irrigation have been widely studied in the last years . A number of contributions have focused on the impacts derived from the use of TWW (Assouline and Narkis, 2013; Lahav et al., 2010; Xu et al., 2010). Changes in soil hydraulic conductivity and clogging processes have been studied in laboratory experiments from soil columns (Lado and Ben-Hur, 2010) and at field scale (Costa, 1999; Minhas et al., 1994). Irrigation with non-conventional water may also lead to the occurrence of contaminants, a major current environmental concern (Valdes-Abellan et al., 2013). Previous studies have considered impacts in a uniform soil media pore structure; less attention has been paid at a microscopic scale and the influence that high-salinity water may have on wettability of soil. Environmental scanning electron microscopy (ESEM) is a useful technique to be applied in soil science to analyse microscopic changes in soil structure or soil wetting patterns. Research applying this technology for wet systems (Donald, 1998) or porous media (Ali et al., 1995) is available, however as far as we know research on soil impacts due to long term irrigation with saline or non-conventional water are much less common. The dynamic mode of the ESEM allows changes of samples from wet to dry by modifying the water vapour pressure and to observe the wetting and drying patterns and interactions between the solid and liquid phase in the soil (Lourenço et al., 2008). Preliminary results of the study at a microscopic scale of soil samples collected before and after three year irrigation with slightly salted water in an experimental plot setup in semi-arid climatic conditions (Alicante, SE Spain) are presented. We will show the micro-structure of soil and undertake a preliminary investigation of wetting and drying of samples using ESEM techniques Differences in the water vapour pressure value at

  5. Long term results of open reduction management of condylar fracture: a 20 years follow-up. Case report.

    PubMed

    Farronato, G; Giannini, L; Galbiati, G; Maspero, C

    2012-10-01

    Management of condylar fracture may be surgical (open reduction) or non surgical (closed treatment). The age of the patient is a key factor in the choice of treatment. Condylar fracture requires early treatment to avoid ankylosis, to reduce facial deformity, aesthetic problems and functional disturbances. The protocol described in this case report showed excellent results and achieved all the treatment objectives. Early mobilization is the key in treating condylar fractures and to allow functional remodelling. It is important that every specialist should be able to suspect condylar fracture when facial asymmetry, joint problems, muscles pain, occlusion or nerve disorders develop after an injury. An early diagnosis can permit an early treatment that prevents esthetic and functional complications. The purpose of this article is to describe the long term clinical and radiological evaluation of unilateral condylar fracture in a teenager patient treated by condylectomy, physiotherapy and fixed appliance therapy. Twenty years follow-up records are presented. PMID:23076028

  6. Substrate reduction therapy with miglustat in chronic GM2 gangliosidosis type Sandhoff: results of a 3-year follow-up.

    PubMed

    Masciullo, Marcella; Santoro, Massimo; Modoni, Anna; Ricci, Enzo; Guitton, Jerome; Tonali, Pietro; Silvestri, Gabriella

    2010-12-01

    GM2 gangliosidosis type Sandhoff is caused by a defect of beta-hexosaminidase, an enzyme involved in the catabolism of gangliosides. It has been proposed that substrate reduction therapy using N-butyl-deoxynojirimycin (miglustat) may delay neurological progression, at least in late-onset forms of GM2 gangliosidosis. We report the results of a 3-year treatment with miglustat (100 mg t.i.d) in a patient with chronic Sandhoff disease manifesting with an atypical, spinal muscular atrophy phenotype. The follow-up included serial neurological examinations, blood tests, abdominal ultrasound, and neurophysiologic, cognitive, brain, and muscle MRI studies. We document some minor effects on neurological progression in chronic Sandhoff disease by miglustat treatment, confirming the necessity of phase II therapeutic trials including early-stage patients in order to assess its putative efficacy in chronic Sandhoff disease. PMID:20821051

  7. Results from a sixteen year study on the effects of oiling from the Exxon Valdez on adult pink salmon returns.

    PubMed

    Brannon, Ernest L; Maki, Alan W; Moulton, Lawrence L; Parker, Keith R

    2006-08-01

    For sixteen years following the 1989 Exxon Valdez oil spill adult returns of pink salmon in Prince William Sound, Alaska were monitored to assess spill effects on survival. No evidence of spill effects was detected for either intertidal or whole-stream spawning fish. From 1989 through 2004 mean densities for oiled and reference streams tracked each other, illustrating similar responses of oiled and reference stream adult populations to naturally changing oceanographic and climactic conditions. Hatchery fish strayed into the study streams, but similar incursions occurred in oiled and reference streams, and their presence was compensated for to eliminate their influence on determining the success of the returning natural populations. These results, showing no detectable effects of oiling on pink salmon spawning populations, are supported by published field studies on pink salmon incubation success in oiled streams. PMID:16487548

  8. Effects of Cognitive Enhancement Therapy on Employment Outcomes in Early Schizophrenia: Results From a Two-Year Randomized Trial

    PubMed Central

    Eack, Shaun M.; Hogarty, Gerard E.; Greenwald, Deborah P.; Hogarty, Susan S.; Keshavan, Matcheri S.

    2013-01-01

    Objective To examine the effects of psychosocial cognitive rehabilitation on employment outcomes in a randomized controlled trial for individuals with early course schizophrenia. Method Early course schizophrenia outpatients (N = 58) were randomly assigned to Cognitive Enhancement Therapy (CET) or an Enriched Supportive Therapy (EST) control and treated for two years. Comprehensive data on cognition and employment were collected annually. Results Individuals treated with CET were significantly more likely to be competitively employed, had greater earnings from employment, and were more satisfied with their employment status by the end of treatment compared to EST recipients. Mediator analyses revealed that improvements in both social and non-social cognition mediated the CET effects on employment. Conclusion CET can help facilitate employment in early schizophrenia, by addressing the cognitive impairments that limit functioning in the disorder. Inclusion of cognitive rehabilitation in social work practice can support more optimal functional recovery from schizophrenia. PMID:23885163

  9. Results of calendar year 1994 monitor well inspection and maintenance program, Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect

    McMaster, B.W.; Jones, S.B.; Sitzler, J.L.

    1995-06-01

    This document is a compendium of results of the calendar year 1994 Monitor Well Inspection and Maintenance Program at the Department of Energy Y-12 Plant in Oak Ridge, Tennessee. This report documents the work relating to well inspections and maintenance requests. Inspections are implemented in order to better assess the condition and maintenance needs of wells that are actively being monitored. Currently this approach calls for inspecting all wells on a routine (annual or triennial) basis which are: (1) in an active sampling program; (2) included in a hydrologic study; or (3) not in service, but not scheduled for plugging and abandonment. Routine inspections help to ensure that representative groundwater samples and hydrologic data are being collected, and contribute to the life expectancy of each well. This report formally presents well inspection and maintenance activities that were conducted at the Y-12 Plant during 1994. All inspections were conducted between April and December.

  10. Immediate Nonfunctional Loading of Two Single-Maxillary Postextractive Implants: 6-Year Postloading Results of Two Case Reports

    PubMed Central

    Ariano, Vincenzo; Mancini, Manuele; Cardi, Andrea; Condò, Roberta; Cerroni, Loredana; Pasquantonio, Guido

    2016-01-01

    Objectives. The aim of the study was to evaluate and compare crestal bone loss of single-maxillary immediate postextractive implants and immediate nonfunctional loading (INFL) during 72 months of follow-up. Material and Methods. Two single titanium implants (Certain Prevail, Biomet 3I, USA) were placed in two patients using INFL technique. Implant stability and crestal bone level were measured on periapical radiographs at 1, 3, and 6 months after surgery. Results. All osseointegrated implants were clinically successful after 6 years of functional loading. Conclusion. Within the limit of the present case report, the paper supports the concept that INFL of single dental implant can be a successful treatment procedure. PMID:27293915

  11. Results of a five-year program of multifrequency monitoring of low-frequency variable radio sources

    NASA Technical Reports Server (NTRS)

    Mitchell, K. J.; Dennison, Brian; Condon, J. J.; Altschuler, Daniel R.; Payne, H. E.; O'Dell, S. L.; Broderick, J. J.

    1994-01-01

    We present the results of a detailed multifrequency monitoring program of low-frequency variable radio sources. This consists of light curves at 318, 430, 606, 880, and 1400 MHz over a 5 year period. The observations were carried out with the Arecibo 305 m radiotelescope and the Green Bank 91 m radio telescope. The spectral characteristics of the variations confirm the general picture that at least two mechanisms are responsible. The first is clearly intrinsic evolution of synchrotron-emitting components as it is manifested by variations that appear first and most strongly at high frequencies, subsequently drifting to lower frequencies with diminished amplitude. The more common type of low-frequency variability, however, dominates at frequencies below approximately 800 MHz, while the variations near 1 GHz are often quite weak. This spectral property is strong evidence that these variations are interstellar refractive scintillation.

  12. Clinical results of meniscus repair with the meniscus arrow: a 4- to 8-year follow-up study.

    PubMed

    Koukoulias, Nikolaos; Papastergiou, Stergios; Kazakos, Konstantinos; Poulios, Georgios; Parisis, Konstantinos

    2007-02-01

    The short-term clinical results of meniscus repair with the meniscus arrow were promising. Unfavorable outcomes were reported in two studies, with longer follow-up, raising concerns about the efficacy of this device. We retrospectively reviewed 62 patients (mean age 23.7 years; range 14-37 years) that underwent all-inside meniscus repair, using the meniscus arrow. Seventeen patients had an isolated meniscus tear (ACL intact group) and 45 patients concomitant ACL rupture that was reconstructed at the same time with the meniscus repair (ACL reconstructed group). All patients followed a non-aggressive rehabilitation protocol. Follow-up was assessed by clinical examination, Lysholm and Tegner score, IKDC knee examination form and KT-2000 arthrometry for the anteroposterior laxity of the reconstructed knees. At an average follow-up of 73 months (range 49-96 months) there were three failures (4.8%), one from the ACL intact group and two from the ACL reconstructed group. One patient developed arthrofibrosis (ACL reconstructed group) that resolved conservatively. Soft tissue irritation at the repair site was noted in three patients. In two patients the symptoms were transient. In the third patient the arrow tip was cut off under local anaesthesia due to saphenous infrapatellar branch irritation and the symptoms resolved (inappropriate arrow size). KT-2000 arthrometry showed that sagittal knee laxity was less than 3 mm in all reconstructed knees. The mean Tegner activity score decreased from 6.7 (pretrauma) to 6.2 (postoperatively). The average Lysholm score was 96, with normal or nearly normal function of all success knees, according to the IKDC knee examination form. Our results show a high clinical success rate of meniscus repair with the meniscus arrow. We found this device both safe and effective. PMID:16858563

  13. Strong Communities for Children: Results of a multi-year community-based initiative to protect children from harm.

    PubMed

    McDonell, James R; Ben-Arieh, Asher; Melton, Gary B

    2015-03-01

    This article reports the evaluation results from Strong Communities for Children, a multi-year comprehensive community-based initiative to prevent child maltreatment and improve children's safety. The outcome study consisted of a survey of a random sample of caregivers of children under age 10 in the Strong Communities service area and a set of comparison communities matched at the block group level on demography. Survey data were collected in two waves 4 years apart. Data were collected on (a) perceptions of the neighborhood and neighbors (e.g., neighboring, collective efficacy), (b) perceptions of neighbors' parenting practices, (c) parental attitudes and beliefs (e.g., parental stress; parental efficacy), and (d) self-reported parenting practices. The survey data were supplemented by data on substantiated reported rates of child abuse and neglect per 1,000 children and ICD-9 coded child injuries suggesting child abuse and neglect per 1,000 children. Compared to the non-intervention sample across time, the Strong Communities samples showed significant changes in the expected direction for social support, collective efficacy, child safety in the home, observed parenting practices, parental stress, parental efficacy, self-reported parenting practices, rates of officially substantiated child maltreatment, and rates of ICD-9 coded child injuries suggesting child maltreatment. These promising results, obtained through multiple methods of evaluation, confirm that a community mobilization strategy can shift norms of parents' care for their children and neighbors' support for one another, so that young children are safer at home and in the community. Replications should be undertaken and evaluated in other communities under diverse auspices. PMID:25747873

  14. Worldwide Evaluations of Quinoa: Preliminary Results from Post International Year of Quinoa FAO Projects in Nine Countries.

    PubMed

    Bazile, Didier; Pulvento, Cataldo; Verniau, Alexis; Al-Nusairi, Mohammad S; Ba, Djibi; Breidy, Joelle; Hassan, Layth; Mohammed, Maarouf I; Mambetov, Omurbek; Otambekova, Munira; Sepahvand, Niaz Ali; Shams, Amr; Souici, Djamel; Miri, Khaled; Padulosi, Stefano

    2016-01-01

    Chenopodium quinoa Willd., a high quality grain crop, is resistant to abiotic stresses (drought, cold, and salt) and offers an optimal source of protein. Quinoa represents a symbol of crop genetic diversity across the Andean region. In recent years, this crop has undergone a major expansion outside its countries of origin. The activities carried out within the framework of the International Year of Quinoa provided a great contribution to raise awareness on the multiple benefits of quinoa as well as to its wider cultivation at the global level. FAO is actively involved in promoting and evaluating the cultivation of quinoa in 26 countries outside the Andean region with the aim to strengthen food and nutrition security. The main goal of this research is to evaluate the adaptability of selected quinoa genotypes under different environments outside the Andean region. This paper presents the preliminary results from nine countries. Field evaluations were conducted during 2013/2014 and 2014/2015 in Asia (Kyrgyzstan and Tajikistan), and the Near East and North African countries (Algeria, Egypt, Iraq, Iran, Lebanon, Mauritania, and Yemen). In each country, the trials were carried out in different locations that globally represent the diversity of 19 agrarian systems under different agro-ecological conditions. Twenty-one genotypes of quinoa were tested using the same experimental protocol in all locations consisting in a randomized complete block design (RCBD) with three replicates. Some genotypes showed higher yields and the Q18 and Q12 landraces displayed greater adaptation than others to new environmental conditions. The Q21 and Q26 landraces were evaluated with stable and satisfactory levels of yield (>1 t.ha(-1)) in each of the different trial sites. This production stability is of considerable importance especially under climate change uncertainty. While these results suggest that this Andean crop is able to grow in many different environments, social, and cultural

  15. Worldwide Evaluations of Quinoa: Preliminary Results from Post International Year of Quinoa FAO Projects in Nine Countries

    PubMed Central

    Bazile, Didier; Pulvento, Cataldo; Verniau, Alexis; Al-Nusairi, Mohammad S.; Ba, Djibi; Breidy, Joelle; Hassan, Layth; Mohammed, Maarouf I.; Mambetov, Omurbek; Otambekova, Munira; Sepahvand, Niaz Ali; Shams, Amr; Souici, Djamel; Miri, Khaled; Padulosi, Stefano

    2016-01-01

    Chenopodium quinoa Willd., a high quality grain crop, is resistant to abiotic stresses (drought, cold, and salt) and offers an optimal source of protein. Quinoa represents a symbol of crop genetic diversity across the Andean region. In recent years, this crop has undergone a major expansion outside its countries of origin. The activities carried out within the framework of the International Year of Quinoa provided a great contribution to raise awareness on the multiple benefits of quinoa as well as to its wider cultivation at the global level. FAO is actively involved in promoting and evaluating the cultivation of quinoa in 26 countries outside the Andean region with the aim to strengthen food and nutrition security. The main goal of this research is to evaluate the adaptability of selected quinoa genotypes under different environments outside the Andean region. This paper presents the preliminary results from nine countries. Field evaluations were conducted during 2013/2014 and 2014/2015 in Asia (Kyrgyzstan and Tajikistan), and the Near East and North African countries (Algeria, Egypt, Iraq, Iran, Lebanon, Mauritania, and Yemen). In each country, the trials were carried out in different locations that globally represent the diversity of 19 agrarian systems under different agro-ecological conditions. Twenty-one genotypes of quinoa were tested using the same experimental protocol in all locations consisting in a randomized complete block design (RCBD) with three replicates. Some genotypes showed higher yields and the Q18 and Q12 landraces displayed greater adaptation than others to new environmental conditions. The Q21 and Q26 landraces were evaluated with stable and satisfactory levels of yield (>1 t.ha−1) in each of the different trial sites. This production stability is of considerable importance especially under climate change uncertainty. While these results suggest that this Andean crop is able to grow in many different environments, social, and cultural

  16. OWN Survey: results after seven years of high-resolution spectroscopic monitoring of Southern O and WN stars

    NASA Astrophysics Data System (ADS)

    Barbá, R.; Gamen, R.; Arias, J. I.; Morrell, N.; Walborn, N. R.; Maíz Apellániz, J.; Sota, A.; Alfaro, E.

    2014-10-01

    We describe briefly the main results of the high-resolution spectroscopic monitoring survey of southern Galactic O- and WN-type stars. The high-resolution spectroscopic monitoring survey of O and WN stars (OWN Survey, Barbá et al. 2010) has completed seven years of sustained campaign, using observational facilities in Chile and Argentina. The selected sample corresponds to those stars for which there is no indication of multiplicity in the Galactic O-star Catalog (Maíz Apellániz et al. 2004) and the VII Catalogue of Galactic WR stars (van der Hucht 2001). We have collected almost 5000 spectra of about 240 O and WN stars. From that sample of 190 O-type stars, we have discovered 146 stars showing radial variations greater than 10 km/s, including 108 new systems, being 56 single-lined spectroscopic binaries, 43 double-lined spectroscopic binaries, and 9 multiple-lined binaries. The new orbital periods spanning from 1.5 to 2200 days. In this work, we present the main result of ``OWN Survey'': the determination of orbits for over fifty O-type spectroscopic binary systems, and the analysis of the spectral-type, luminosty, period, eccentricity, and mass-ratio distributions. This result is unprecedented in the context of massive binary stars, since we are almost doubling the number of Galactic O-type star systems with known orbits.

  17. [Pollen content of the Paris air: comparison of the results obtained by two samplers for the year 2003].

    PubMed

    Distigny, C; Polenne, J P; Bordenave, L; Bex, V; Squinazi, F

    2004-09-01

    During the 2003 season, a second pollen collector has been established in Paris city (Audubon site) to study the representativeness of the initial collector situated on the roof of the Pasteur Institute. The Hygiene Laboratory of Paris followed the pollen counts from the two collectors, during the period going from May to September. Both the samplers are Lanzoni model with a flow rate of 10 l x min(-1). The quantitative results show that no statistical difference exists between the pollen counts obtained from the 2 sites (Mann-Withney test, p > .05). The dominant species are Urticaceae, Poacae and Castenea species for the 2 collectors. Their counts are similar except for Poacae whose results are higher at the Audubon site. The collection period do not take into account the pollen production period of many trees species because of the late installation of the collector on the Audubon site. The results show that the two sites chosen for the study of pollen distribution are comparable. Nevertheless, the comparative study should be maintained on the next year to get more details about the observed differences and to collect the early trees pollen. PMID:15529829

  18. 2011 Year-End Poll of Employers: A Look at Hiring and Salary Projections for the Coming Year. Summary of Results

    ERIC Educational Resources Information Center

    Estrada, Rebecca

    2011-01-01

    Not only do more companies plan to hire in 2012, they plan to hire at similar or increased levels compared to 2011, according to responses to the 2011 Year-End Poll of Employers of the Graduate Management Admission Council (GMAC). The annual poll of employers, which the Council conducted from November 2 to November 16, 2011, garnered responses…

  19. Physics Enrollments in Two-Year Colleges: Results from the 2012 Survey of Physics in Two-Year Colleges. Focus On

    ERIC Educational Resources Information Center

    White, Susan; Chu, Raymond

    2013-01-01

    This "Focus On" first considers the role two-year colleges (TYCs) play in post-secondary physics education. In their 2007 Survey of Undergraduate Seniors in degree-granting physics departments, the authors asked students if they had begun their post-secondary education at a TYC. Nine percent of the physics undergraduate seniors in 2007…

  20. A rapid screening tool for psychological distress in children 3–6years old: results of a validation study

    PubMed Central

    2012-01-01

    Background The mental health needs of young children in humanitarian contexts often remain unaddressed. The lack of a validated, rapid and simple tool for screening combined with few mental health professionals able to accurately diagnose and provide appropriate care mean that young children remain without care. Here, we present the results of the principle cross-cultural validation of the “Psychological Screening for Young Children aged 3 to 6” (PSYCAa3-6). The PSYCa 3–6 is a simple scale for children 3 to 6 years old administered by non-specialists, to screen young children in crises and thereby refer them to care if needed. Methods This study was conducted in Maradi, Niger. The scale was translated into Hausa, using corroboration of independent translations. A cross-cultural validation was implemented using quantitative and qualitative methods. A random sample of 580 mothers or caregivers of children 3 to 6 years old were included. The tool was psychometrically examined and diagnostic properties were assessed comparing the PSYCa 3–6 against a clinical interview as the gold standard. Results The PSYCa 3–6 Hausa version demonstrated good concurrent validity, as scores correlated with the gold standard and the Clinical Global Impression Severity Scale (CGI-S) [rho = 0.41, p-value = 0.00]. A reduction procedure was used to reduce the scale from 40 to 22 items. The test-retest reliability of the PSYCa 3–6 was found to be high (ICC 0.81, CI95% [0.68; 0.89]). In our sample, although not the purpose of this study, approximately 54 of 580 children required subsequent follow-up with a psychologist. Conclusions To our knowledge, this is the first validation of a screening scale for children 3 to 6 years old with a cross-cultural validation component, for use in humanitarian contexts. The Hausa version of the PSYCa 3–6 is a reliable and a valuable screening tool for psychological distress. Further studies to replicate our findings and additional

  1. Diatoms as a proxy for climate reconstruction for the last 2000 years from the Norwegian and Iberian Shelves: preliminary results.

    NASA Astrophysics Data System (ADS)

    Stroynowska, Z.; Abrantes, F.; Klitgaard, D.; Sejrup, H. P.; Frances, G.; Diz, P.; Berstad, I.

    High-resolution quantitative diatom abundances and assemblages have been reconstructed from cores retrieved from the Northwest Norwegian Margin, and from the Ria de Muros, in Northwestern Spain. The Norwegian core is subject to oceanic processes and lies near the boundary of the Norwegian current (63°45'44"N; 05°15'18.5"E), whereas the Muros core is located in the mouth of the estuary (42°45.1N, 9°02.2W ) and is influenced by both oceanic and terrestrial processes. As yet, there are few high-resolution data from either region that would permit climatic investigation on a decadal scale. Core P1-003MC retrieved from the Norwegian Margin has been sampled at half centimetre intervals, giving a resolution of 4-9 years/cm and core EUGC-3B taken from the Ria de Muros has been sampled every centimetre and has a resolution of 12-14 years/cm. Both these sedimentation rates are based on age models reconstructed from C14 and Lead 210 dating. Reservoir correction applied to C14 is 400 years. Preliminary results of absolute diatom abundances show that from both cores, variability is independent of dissolution or fragmentation. Maximum total abundance of diatoms/gram in the Norwegian core is 10 .6 valves/g, whereas in the Muros the peak of total diatom abundance in valves/g reaches 10. 7 valves/g. A difference that can be related to better preservation conditions in the Ria. Data from the Norwegian Margin show clear sub-decadal variability, with minimum diatom productivity during the Little Ice Age (around 1540 until the 1900s), as indicated by the delta 18O record and by previous publications. A significant increase in diatom productivity is found during a warming phase at around 1920. The Ria is found to have a higher species diversity, with significant injections of freshwater species that can be correlated to terrigenous input and are further supported by the instrumental record for changes in precipitation for the region. Oceanic influence in the Ria is marked clearly by

  2. Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study

    PubMed Central

    2011-01-01

    Introduction Co-morbidity and mortality due to cardiovascular disease (CVD) are increased in patients with rheumatoid arthritis (RA). Most published studies in this field are retrospective or cross sectional. We investigated the presence of traditional and disease related risk factors for CVD at the onset of RA and during the first five years following diagnosis. We also evaluated their potential for predicting a new cardiovascular event (CVE) during the five-year follow-up period and the modulatory effect of pharmacological treatment. Methods All patients from the four northern-most counties of Sweden with early RA are, since December 1995, consecutively recruited at diagnosis (T0) into a large survey on the progress of the disease. Information regarding cardiovascular co-morbidity and related predictors was collected from clinical records and supplemented with questionnaires. By April 2008, 700 patients had been included of whom 442 patients had reached the five-year follow-up (T5). Results Among the 442 patients who reached T5 during the follow-up period, treatment for hypertension increased from 24.5 to 37.4% (P < 0.001)), diagnosis of diabetes mellitus (DM) from 7.1 to 9.5% (P < 0.01) whilst smoking decreased from 29.8 to 22.4% (P < 0.001) and the BMI from 26.3 to 25.8 (P < 0.05), respectively. By T5, 48 patients had suffered a new CVE of which 12 were fatal. A total of 23 patients died during the follow-up period. Age at disease onset, male sex, a previous CVE, DM, treatment for hypertension, triglyceride level, cumulative disease activity (area under the curve (AUC) disease activity score (DAS28)), extra-articular disease, corticosteroid use, shorter duration of treatment with disease modifying anti-rheumatic drugs (DMARDs) and use of COX-2 inhibitors increased the hazard rate for a new CVE. A raised erythrocyte sedimentation rate (ESR) at inclusion and AUC DAS28 at six months increased the hazard rate of CVE independently whilst DMARD treatment was

  3. Progression of fibromyalgia: results from a 2-year observational fibromyalgia and chronic pain study in the US

    PubMed Central

    Adams, Edgar H; McElroy, Heather J; Udall, Margarita; Masters, Elizabeth T; Mann, Rachael M; Schaefer, Caroline P; Cappelleri, Joseph C; Clair, Andrew G; Hopps, Markay; Daniel, Shoshana R; Mease, Philip; Silverman, Stuart L; Staud, Roland

    2016-01-01

    Background A previous fibromyalgia (FM) research reports that 20%–47% of diagnosed patients may not meet the study definition of FM 1–2 years after diagnosis. The aim of this study was to gain a better understanding of the progression of FM in a geographically diverse cohort over a 2-year time period. Methods This cohort study followed 226 subjects recruited online to assess FM and chronic widespread pain (CWP) diagnosis stability over time. At enrollment (baseline), subjects provided informed consent, completed an online questionnaire consisting of the London Fibromyalgia Epidemiology Study Screening Questionnaire to screen for CWP (bilateral pain above/below waist lasting ≥1 week in the past 3 months), visited a site for physician evaluation for FM, and completed a questionnaire with validated patient-reported outcome instruments. Subjects were classified into mutually exclusive groups: FM+CWP+ (screened positive for CWP and received physician diagnosis of FM), FM−CWP+ (screened positive for CWP but did not receive physician diagnosis of FM), and FM−CWP− (screened negative for CWP). Approximately 2 years later (follow-up), subjects were reassessed at the same study site and completed a questionnaire with the same patient-reported outcomes. Results Seventy-six FM+CWP+ subjects completed assessments at both time points; 56 (73.7%) met the FM study definition at follow-up. Twenty subjects no longer met the FM study definition (eleven became FM−CWP− and nine became FM−CWP+). Ten subjects (two from FM−CWP− and eight from FM−CWP+) transitioned into the FM+CWP+ group at follow-up; they reported more tender points and pain interference with sleep and worse physical function at baseline compared with subjects who did not transition to FM+CWP+. Most (76.7%) of the subjects who transitioned into/out of FM+CWP+ experienced changes in CWP, number of positive tender points, or both. Conclusion The results suggest that some FM+CWP+ patients experience

  4. The Economic Benefits Resulting from the First 8 Years of the Global Programme to Eliminate Lymphatic Filariasis (2000–2007)

    PubMed Central

    Chu, Brian K.; Hooper, Pamela J.; Bradley, Mark H.; McFarland, Deborah A.; Ottesen, Eric A.

    2010-01-01

    Background Between 2000–2007, the Global Programme to Eliminate Lymphatic Filariasis (GPELF) delivered more than 1.9 billion treatments to nearly 600 million individuals via annual mass drug administration (MDA) of anti-filarial drugs (albendazole, ivermectin, diethylcarbamazine) to all at-risk for 4–6 years. Quantifying the resulting economic benefits of this significant achievement is important not only to justify the resources invested in the GPELF but also to more fully understand the Programme's overall impact on some of the poorest endemic populations. Methodology To calculate the economic benefits, the number of clinical manifestations averted was first quantified and the savings associated with this disease prevention then analyzed in the context of direct treatment costs, indirect costs of lost-labor, and costs to the health system to care for affected individuals. Multiple data sources were reviewed, including published literature and databases from the World Health Organization, International Monetary Fund, and International Labour Organization Principal Findings An estimated US$21.8 billion of direct economic benefits will be gained over the lifetime of 31.4 million individuals treated during the first 8 years of the GPELF. Of this total, over US$2.3 billion is realized by the protection of nearly 3 million newborns and other individuals from acquiring lymphatic filariasis as a result of their being born into areas freed of LF transmission. Similarly, more than 28 million individuals already infected with LF benefit from GPELF's halting the progression of their disease, which results in an associated lifetime economic benefit of approximately US$19.5 billion. In addition to these economic benefits to at-risk individuals, decreased patient services associated with reduced LF morbidity saves the health systems of endemic countries approximately US$2.2 billion. Conclusions/Significance MDA for LF offers significant economic benefits. Moreover, with

  5. Programs and Practices that Retain Students from the First to Second Year: Results from a National Study

    ERIC Educational Resources Information Center

    DeAngelo, Linda

    2014-01-01

    In this chapter findings from a nationally representative longitudinal study offer insights into how the experiences students have during their first college year affect their intention to be retained at their initial college for the second year.

  6. Large and Small Scale Nitrogen and Phosporous Manipulation Experiment in a Tree-Grass Ecosystem: first year of results

    NASA Astrophysics Data System (ADS)

    Migliavacca, Mirco; Perez Priego, Oscar; El-Madany, Tarek; Guan, JinHong; Carrara, Arnaud; Fava, Francesco; Moreno, Gerardo; Kolle, Olaf; Rossini, Micol; Schrumpf, Marion; Julitta, Tommaso; Reichstein, Markus

    2015-04-01

    Recent studies have shown how human induced N/P imbalances affect essential ecosystem processes (e.g. photosynthesis, plant growth rate, respiration), and might be particularly important in water-limited ecosystems. In this contribution we will present the experimental design and the results of the first year of two nutrient manipulation experiments conducted at different spatial scale. In the first experiment a cluster of 2 eddy covariance (EC) flux towers has been set up beside a long-term EC site (Las Majadas del Tietar, Spain). Sites are selected in a way to have similar nutrient conditions, canopy structure, and stoichiometry of the different vegetation and soil pools. Two of the three footprints will be manipulated with addition of N and NP fertilizer at the beginning of 2015. The comparison of the three EC flux towers installed during the first year of the experiment (without fertilization) will be shown. We characterized the differences of the responses of carbon and water fluxes measured by the EC systems to environmental drivers, and structural and biophysical properties of the canopy. The second experiment was conducted over a Mediterranean grassland, where 16 plots of 10x10 meters that were manipulated by adding nutrient (N, P, and NP). The overall objective was to investigate the response of the gross primary productivity (GPP), assessed by using transparent transient-state canopy chambers, to different nutrient availability. The second objective was to evaluate the capability of hyperspectral data and Solar induced fluorescence to track short- and long-term GPP and light use efficiency variation under different N and P fertilization treatments. Spectral vegetation indices (VIs) were acquired manually using high resolution spectrometers (HR4000, OceanOptics, USA) along a phenological cycle. The VIs used included photochemical reflectance index (PRI), MERIS terrestrial-chlorophyll index (MTCI) and normalized difference vegetation index (NDVI). Solar

  7. First Results of 3 Year Monitoring of Red Wood Ants' Behavioural Changes and Their Possible Correlation with Earthquake Events

    NASA Astrophysics Data System (ADS)

    Berberich, Gabriele; Berberich, Martin; Grumpe, Arne; Wöhler, Christian; Schreiber, Ulrich

    2013-04-01

    Short-term earthquake predictions with an advance warning of several hours or days can currently not be performed reliably and remain limited to only a few minutes before the event. Abnormal animal behaviours prior to earthquakes have been reported previously but their detection creates problems in monitoring and reliability. A different situation is encountered for red wood ants (RWA; Formica rufa-group (Hymenoptera: Formicidae). They have stationary nest sites on tectonically active, gas-bearing fault systems. These faults may be potential earthquake areas and are simultaneously information channels deeply reaching into the crust. A particular advantage of monitoring RWA is their high sensitivity to environmental changes. Besides an evolutionarily developed extremely strong temperature sensitivity of 0.25 K, they have chemoreceptors for the detection of CO2 concentrations and a sensitivity for electromagnetic fields. Changes of the electromagnetic field are discussed or short-lived "thermal anomalies" are reported as trigger mechanisms for bioanomalies of impending earthquakes. For 3 years, we have monitored two Red Wood Ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), 24/7 by high-resolution cameras equipped with a colour and infrared sensor. In the Neuwied Basin, an average of about 100 earthquakes per year with magnitudes up to M 3.9 occur located on different tectonic fault regimes (strike-slip faults and/or normal or thrust faults). The RWA mounds are located on two different fault regimes approximately 30 km apart. First results show that the ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants' behaviour hours before the earthquake event: The nocturnal rest phase and daily activity are suppressed, and standard daily routine is continued not before the next day. Additional parameters that might have an effect on the ants' daily routine

  8. The Gulf War depleted uranium cohort at 20 years: bioassay results and novel approaches to fragment surveillance.

    PubMed

    McDiarmid, Melissa A; Gaitens, Joanna M; Hines, Stella; Breyer, Richard; Wong-You-Cheong, Jade J; Engelhardt, Susan M; Oliver, Marc; Gucer, Patricia; Kane, Robert; Cernich, Alison; Kaup, Bruce; Hoover, Dennis; Gaspari, Anthony A; Liu, Juan; Harberts, Erin; Brown, Lawrence; Centeno, Jose A; Gray, Patrick J; Xu, Hanna; Squibb, Katherine S

    2013-04-01

    During the 1991 GulfWar, U.S. service members were exposed to depleted uranium (DU) through friendly-fire incidents involving DU munitions and vehicles protected by DU armor. Routes of exposure to DU involved inhalation of soluble and insoluble DU oxide particles, wound contamination, and retained embedded DU metal fragments that continue to oxidize in situ and release DU to the systemic circulation. A biennial health surveillance program established for this group of Veterans by the U.S. Department of Veterans Affairs has shown continuously elevated urine DU concentrations in the subset of veterans with embedded fragments for over 20 years. While the 2011 assessment was comprehensive, few clinically significant U-related health effects were observed. This report is focused on health outcomes associated with two primary target organs of concern for long term effects of this combat-related exposure to DU. Renal biomarkers showed minimal DU-related effects on proximal tubule function and cytotoxicity, but significant biomarker results were observed when urine concentrations of multiple metals also found in fragments were examined together. Pulmonary tests and questionnaire results indicate that pulmonary function after 20 y remains within the clinical normal range. Imaging of DU embedded fragment-associated tissue for signs of inflammatory or proliferative reactions possibly associated with foreign body transformation or with local alpha emissions from DU was also conducted using PET-CT and ultrasound. These imaging tools may be helpful in guiding decisions regarding removal of fragments. PMID:23439138

  9. Hybrid Therapy in Patients with Complex Peripheral Multifocal Steno-obstructive Vascular Disease: Two-Year Results

    SciTech Connect

    Cotroneo, Antonio Raffaele; Iezzi, Roberto Marano, Giuseppe; Fonio, Paolo; Nessi, Franco; Gandini, Giovanni

    2007-06-15

    Purpose. To report the 2-year results after hybrid (combined surgical-endovascular) therapy in patients with complex peripheral multifocal steno-obstructive vascular disease. Methods. From September 2001 through April 2003, 47 combined surgical-endovascular procedures were performed in a single session in 44 patients with peripheral occlusive artery disease. Although the common femoral artery is usually treated with open surgery, endoluminal procedures were performed upward in 23 patients (group A), distally in 18 patients (group B), and both upward and downward of the area treated with open surgery in 3 patients (group C). Patients underwent clinical assessment and color duplex ultrasonography examination at 1, 3, 6, 12, 18, and 24 months after the procedure. Results. The technical success rate was 100%. Two patients died, at 2 and 19 months after treatment, respectively, both from myocardial infarction. Primary and primary-assisted patency rates were 86.2% and 90.8% at 6 months and 79.1% and 86.1% at 24 months, respectively. Thirty-three patients remained free of symptoms, without any secondary interventions, which corresponded to a primary patency rate of 78.6% (33 of 42). Conclusion. Combined therapy simplifies and allows the one-step treatment of patients with complex peripheral multifocal steno-obstructive vascular disease that has indications for revascularization, and it provides excellent long-term patency rates.

  10. Results at seven years after the use of intracamerular cefazolin as an endophthalmitis prophylaxis in cataract surgery

    PubMed Central

    2012-01-01

    Background To evaluate results after seven years using prophylactic intracameral cefazolin for the prevention of endophthalmitis in cataract surgery. Methods A prospective, observational study of all patients submitted to cataract surgery over the period January 1996 to December 2009. All cases of postoperative endophthalmitis over that period were reviewed. The patients were classified in two groups: Group 1 (11,696 patients) operated on between January 1996 and December 2002, Group 2 (13,305 patients) between January 2003 and December 2009 (in whom a 1 mg/0.1 bolus of intracameral cefazolin was instilled). Results During the study period, 76 cases of endophthalmitis were observed in Group 1, and seven in Group 2. The rate of postoperative endophthalmitis reduced from 0.63% to 0.05% with a cefazolin injection. The relative risk (RR) for endophthalmitis in Group 1 against group 2 was 11.45 [95% CI 5.72-22.84, p < 0.001]. Conclusions An intracameral bolus injection of cefazolin (1 mg in 0.1 ml solution) at the conclusion of the cataract surgery significantly reduced the rate of postoperative endophthalmitis. PMID:22272570

  11. The 3-6-year results of a modular noncemented low-bending stiffness hip implant. A preliminary study.

    PubMed

    Cameron, H U

    1993-06-01

    A review of the 3-6-year clinical and radiographic results of a modular noncemented stem has been carried out. This is a three-part stem consisting of a head, stem, and proximal sleeve. The stems are split distally like a clothespin in the coronal plane to reduce bending stiffness. No mechanical failures have occurred, including no bead separation from the single-layer porous-coated taper lock sleeves. Of the 48 cases, 13 had smooth stems distally while the rest were fluted. Five of the fluted stems were solid, that is, nonsplit. Clinical results are 93.7% excellent, 4.2% good, and 2.1% poor with the Harris hip rating. There have been no revisions. Thigh pain incidence with the distal split stem was 4.4%. Radiographic follow-up evaluations revealed nonprogressive radiolucency around one of the ingrowth sleeves. When inserted in varus the smooth stems developed some radiolucency around the distal end. Fluting of the stem appeared to prevent this. PMID:8326303

  12. Statistical analyses of the results of 25 years of beach litter surveys on the south-eastern North Sea coast.

    PubMed

    Schulz, Marcus; Clemens, Thomas; Förster, Harald; Harder, Thorsten; Fleet, David; Gaus, Silvia; Grave, Christel; Flegel, Imme; Schrey, Eckart; Hartwig, Eike

    2015-08-01

    In the North Sea, the amount of litter present in the marine environment represents a severe environmental problem. In order to assess the magnitude of the problem and measure changes in abundance, the results of two beach litter monitoring programmes were compared and analysed for long-term trends applying multivariate techniques. Total beach litter pollution was persistently high. Spatial differences in litter abundance made it difficult to identify long-term trends: Partly more than 8000 litter items year(-1) were recorded on a 100 m long survey site on the island of Scharhörn, while the survey site on the beach on the island of Amrum revealed abundances lower by two orders of magnitude. Beach litter was dominated by plastic with mean proportions of 52%-91% of total beach litter. Non-parametric time series analyses detected many significant trends, which, however, did not show any systematic spatial patterns. Cluster analyses partly led to groupings of beaches according to their expositions to sources of litter, wind and currents. Surveys in short intervals of one to two weeks were found to give higher annual sums of beach litter than the quarterly surveys of the OSPAR method. Surveys at regular intervals of four weeks to five months would make monitoring results more reliable. PMID:26026589

  13. Medical Injection Use Among Adults and Adolescents Aged 15 to 64 Years in Kenya: Results From a National Survey

    PubMed Central

    Kimani, Daniel; Kamau, Rachel; Ssempijja, Victor; Robinson, Katherine; Oluoch, Tom; Njeru, Mercy; Mwangi, Jane; Njogu, David; Kim, Andrea A.

    2016-01-01

    Background Unsafe medical injections remain a potential route of HIV transmission in Kenya. We used data from a national survey in Kenya to study the magnitude of medical injection use, medication preference, and disposal of medical waste in the community. Methods The Kenya AIDS Indicator Survey 2012 was a nationally representative population-based survey. Among participants aged 15–64 years, data were collected regarding medical injections received in the year preceding the interview; blood samples were collected from participants for HIV testing. Results Of the 13,673 participants who answered questions on medical injections, 35.9% [95% confidence interval (CI): 34.5 to 37.3] reported receiving ≥1 injection in the past 12 months and 51.2% (95% CI: 49.7 to 52.8) preferred receiving an injection over a pill. Among those who received an injection from a health care provider, 95.9% (95% CI: 95.2 to 96.7) observed him/her open a new injection pack, and 7.4% (95% CI: 6.4 to 8.4) had seen a used syringe or needle near their home or community in the past 12 months. Men who had received ≥1 injection in the past 12 months (adjusted odds ratio, 3.2; 95% CI: 1.2 to 8.9) and women who had received an injection in the past 12 months, not for family planning purposes (adjusted odds ratio, 2.6; 95% CI: 1.2 to 5.5), were significantly more likely to be HIV infected compared with those who had not received medical injection in the past 12 months. Conclusions Injection preference may contribute to high rates of injections in Kenya. Exposure to unsafe medical waste in the community poses risks for injury and infection. We recommend that community- and facility-based injection safety strategies be integrated in disease prevention programs. PMID:24413041

  14. Older workers in the construction industry: results of a routine health examination and a five year follow up.

    PubMed Central

    Arndt, V; Rothenbacher, D; Brenner, H; Fraisse, E; Zschenderlein, B; Daniel, U; Schuberth, S; Fliedner, T M

    1996-01-01

    OBJECTIVE: To describe the health status of older construction workers and the occurrence of early retirement due to disability or of mortality within a five year follow up. METHODS: Firstly, a cross sectional study was performed among 4958 employees in the German construction industry, aged 40-64 years, who underwent standardised routine occupational health examinations in 1986-8. The study population included plumbers, carpenters, painters/varnishers, plasterers, unskilled workers, and white collar workers (control group). Job specific prevalence and age adjusted relative prevalence were calculated for hearing loss, abnormal findings at lung auscultation, reduced forced expiratory volume, increased diastolic blood pressure, abnormalities in the electrocardiogram, increased body mass index, hypercholesterolaemia, increased liver enzymes, abnormal findings in an examination of the musculoskeletal system, and abnormalities of the skin. Secondly, follow up for disability and all cause mortality was ascertained between 1992 and 1994 (mean follow up period = 4.5 y). Job specific crude rates were calculated for the occurrence of early retirement due to disability and for all cause mortality. With Cox's proportional hazards model, job specific relative risks, adjusted for age, nationality, and smoking were obtained. RESULTS: Compared with the white collar workers, a higher prevalence of hearing deficiencies, signs of obstructive lung diseases, increased body mass index, and musculoskeletal abnormalities were found among the construction workers at the baseline exam. During the follow up period, 141 men died and 341 men left the labour market due to disability. Compared with white collar workers, the construction workers showed a 3.5 to 8.4-fold increased rate of disability (P < 0.05 for all occupational groups) and a 1.2 to 2.1-fold increased all cause mortality (NS). CONCLUSIONS: This study shows the need and possibilities for further health promotion in workers

  15. 10-Year Experience With I-125 Prostate Brachytherapy at the Princess Margaret Hospital: Results for 1,100 Patients

    SciTech Connect

    Crook, Juanita; Borg, Jette; Evans, Andrew; Toi, Ants; Saibishkumar, E.P.; Fung, Sharon; Ma, Clement

    2011-08-01

    Purpose: To report outcomes for 1,111 men treated with iodine-125 brachytherapy (BT) at a single institution. Methods and Materials: A total of 1,111 men (median age, 63) were treated with iodine-125 prostate BT for low- or intermediate-risk prostate cancer between March 1999 and November 2008. Median prostate-specific antigen (PSA) level was 5.4 ng/ml (range, 0.9-26.1). T stage was T1c in 66% and T2 in 34% of patients. Gleason score was 6 in 90.1% and 7 or 8 in 9.9% of patients. Neoadjuvant hormonal therapy (2-6 months course) was used in 10.1% of patients and combined external radiotherapy (45 Gy) with BT (110 Gy) in 4.1% (n = 46) of patients. Univariate and multivariate Cox proportional hazards were used to determine predictors of failure. Results: Median follow-up was 42 months (range, 6-114), but for biochemical freedom from relapse, a minimum PSA test follow-up of 30 months was required (median 54; n = 776). There were 27 failures, yielding an actuarial 7-year disease-free survival rate of 95.2% (96 at risk beyond 84 months). All failures underwent repeat 12-core transrectal ultrasound -guided biopsies, confirming 8 local failures. On multivariate analysis, Gleason score was the only independent predictor of failure (p = 0.001; hazard ratio, 4.8 (1.9-12.4). Median International Prostate Symptom score from 12 to 108 months ranged between 3 and 9. Of the men reporting baseline potency, 82.8% retained satisfactory erectile function beyond 5 years. Conclusion: Iodine-125 prostate BT is a highly effective treatment option for favorable- and intermediate-risk prostate cancer and is associated with maintenance of good urinary and erectile functions.

  16. Cognitive Enhancement Therapy Protects Against Gray Matter Loss in Early Schizophrenia: Results From a Two-Year Randomized Controlled Trial

    PubMed Central

    Eack, Shaun M.; Hogarty, Gerard E.; Cho, Raymond Y.; Prasad, Konasale M. R.; Greenwald, Deborah P.; Hogarty, Susan S.; Keshavan, Matcheri S.

    2013-01-01

    Context Cognitive rehabilitation has shown efficacy for improving cognition in patients with schizophrenia, but the underlying neurobiologic changes that occur during these treatments and support cognitive improvement are not well known. Objective To examine differential changes in brain morphology in early schizophrenia during cognitive rehabilitation versus supportive therapy. Design A 2-year, randomized-controlled trial with annual structural magnetic resonance imaging and cognitive assessments. Setting An outpatient research clinic at a university-based medical center providing comprehensive care services for patients with severe mental illness. Patients A total of 53 symptomatically stable, but cognitively disabled outpatients in the early course of schizophrenia or schizoaffective disorder. Interventions Cognitive enhancement therapy is an integrated approach to the remediation of cognitive impairments in schizophrenia that utilizes computer-assisted neurocognitive training and group-based social-cognitive exercises. Enriched supportive therapy is an illness management approach that provides psychoeducation and teaches applied coping strategies. Main Outcome Measures Broad areas of frontal and temporal gray matter change were analyzed using longitudinal voxel-based morphometry methods employing mixed-effects models, followed by volumetric analyses of regions demonstrating significant differential changes between treatment groups. Results Patients receiving cognitive enhancement therapy demonstrated significantly greater preservation of gray matter volume over the course of two years in the left hippocampus, parahippocampal gyrus, and fusiform gyrus, and significantly greater gray matter increases in the left amygdala (all corrected P < .040), compared with those receiving enriched supportive therapy. Less gray matter loss in the left parahippocampal and fusiform gyrus, and greater gray matter increases in the left amygdala were significantly related to

  17. Long-term active layer and ground surface temperature trends: results of 12 years of observations at Alaskan CALM sites

    NASA Astrophysics Data System (ADS)

    Shiklomanov, N. I.; Nelson, F. E.; Streletskyi, D. A.; Klene, A. E.; Schimek, M.; Little, J.

    2006-12-01

    The uppermost layer of seasonal thawing above permafrost (the active layer) is an important regulator of energy and mass fluxes between the surface and the atmosphere in the polar regions. The Circumpolar Active Layer Monitoring (CALM) program is a network of sites at which data about active-layer thickness (ALT) and dynamics are collected. CALM was established in the 1990s to observe and detect the long-term response of the active layer and near-surface permafrost to changes in climate. Active layer monitoring is an important component of efforts to assess the effects of global change in permafrost environments. CALM strategies are evolving; this presentation showcases some additions to CALM observation procedures designed to monitor processes and detect changes not anticipated in the original CALM protocol of the early 1990s. In this study we used data from 12 (1995-2006) years of extensive, spatially oriented field observations at CALM sites in northern Alaska to examine landscape-specific spatial and temporal trends in active-layer thickness and air and ground surface temperature. Despite an observed increase in air temperature, active-layer thickness exhibited a decreasing trend over the study period. This result indicates that soil consolidation accompanying penetration of thaw into an ice-rich stratum at the base of the active layer has resulted in subsidence of the surface with little or no apparent thickening of the active layer, as traditionally defined. Differential Global Positioning Systems (DGPS) technology was used to detect frost heave and thaw settlement within representative landscapes. Preliminary results indicate that heave and settlement follow patterns of spatial variation similar to those of active-layer thickness. To evaluate the effect of vegetation on ground surface temperature, several heat-transfer coefficients were estimated, including land cover specific thermal diffusivity and empirical n-factors.

  18. Surveillance results of depleted uranium-exposed Gulf War I veterans: sixteen years of follow-up.

    PubMed

    McDiarmid, M A; Engelhardt, S M; Dorsey, C D; Oliver, M; Gucer, P; Wilson, P D; Kane, R; Cernich, A; Kaup, B; Anderson, L; Hoover, D; Brown, L; Albertini, R; Gudi, R; Squibb, K S

    2009-01-01

    As part of a longitudinal surveillance program, 35 members of a larger cohort of 77 Gulf War I veterans who were victims of depleted uranium (DU) "friendly fire" during combat underwent a 3-day clinical assessment at the Baltimore Veterans Administration Medical Center (VAMC). The assessment included a detailed medical history, exposure history, physical examination, and laboratory studies. Spot and 24-h urine collections were obtained for renal function parameters and for urine uranium (U) measures. Blood U measures were also performed. Urine U excretion was significantly associated with DU retained shrapnel burden (8.821 mug U/g creatinine [creat.] vs. 0.005 mug U/g creat., p = .04). Blood as a U sampling matrix revealed satisfactory results for measures of total U with a high correlation with urine U results (r = .84) when urine U concentrations were >/=0.1 mug/g creatinine. However, isotopic results in blood detected DU in only half of the subcohort who had isotopic signatures for DU detectable in urine. After stratifying the cohort based on urine U concentration, the high-U group showed a trend toward higher concentrations of urine beta(2) microglobulin compared to the low-U group (81.7 v. 69.0 mug/g creat.; p = .11 respectively) and retinol binding protein (48.1 vs. 31.0 mug/g creat.; p = .07 respectively). Bone metabolism parameters showed only subtle differences between groups. Sixteen years after first exposure, this cohort continues to excrete elevated concentrations of urine U as a function of DU shrapnel burden. Although subtle trends emerge in renal proximal tubular function and bone formation, the cohort exhibits few clinically significant U-related health effects. PMID:18979351

  19. Phase relations and formation of chromium-rich phases in the system Mg4Si4O12-Mg3Cr2Si3O12 at 10-24 GPa and 1,600 °C

    NASA Astrophysics Data System (ADS)

    Sirotkina, E. A.; Bobrov, A. V.; Bindi, L.; Irifune, T.

    2015-01-01

    Phase relations in the system Mg4Si4O12-Mg3Cr2Si3O12 were studied at 10-24 GPa and 1,600 °C using a high-pressure Kawai-type multi-anvil apparatus. We investigated the full range of starting compositions for the knorringite-majorite system to derive a P- X phase diagram and synthesize garnets of a wide compositional range. Samples synthesized in the pressure range 10-14 GPa contain knorringite-majorite garnet and Cr-bearing pyroxene. With increasing Cr content in the starting materials, an association of knorringite-majorite garnet and eskolaite is formed. Garnets contain a significant portion of majorite (>10 mol%) even for a pure Mg3Cr2Si3O12 starting composition. Knorringite-majorite garnets were obtained in the pressure range from 10 to 20 GPa. With increasing pressure, the phase assemblages include Cr-bearing MgSiO3 akimotoite and MgSiO3 bridgmanite, as well as MgCr2O4 with calcium titanate structure, and stishovite. Single-crystal X-ray diffraction shows that the incorporation of Cr into the structure of garnet, as well as MgSiO3 akimotoite, and bridgmanite results in an increase in their unit cell parameters. Results of the experimental high-pressure investigation of the pseudo-binary system Mg4Si4O12-Mg3Cr2Si3O12 (SiO2-MgO-Cr2O3) may be applied to the origin of high chromium phases (mostly garnet) found as inclusions in peridotitic diamonds and formed in bulk rock compositions with high Cr/Al ratios in relation to the primitive mantle.

  20. Early Results of Three-Year Monitoring of Red Wood Ants’ Behavioral Changes and Their Possible Correlation with Earthquake Events

    PubMed Central

    Berberich, Gabriele; Berberich, Martin; Grumpe, Arne; Wöhler, Christian; Schreiber, Ulrich

    2013-01-01

    Simple Summary For three years (2009–2012), two red wood ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), have been monitored 24/7 by high-resolution cameras. Early results show that ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants’ behavior hours before the earthquake: the nocturnal rest phase and daily activity are suppressed, and standard daily routine does not resume until the next day. At present, an automated image evaluation routine is being applied to the video streams. Based on this automated approach, a statistical analysis of the ant behavior will be carried out. Abstract Short-term earthquake predictions with an advance warning of several hours or days are currently not possible due to both incomplete understanding of the complex tectonic processes and inadequate observations. Abnormal animal behaviors before earthquakes have been reported previously, but create problems in monitoring and reliability. The situation is different with red wood ants (RWA; Formica rufa-group (Hymenoptera: Formicidae)). They have stationary mounds on tectonically active, gas-bearing fault systems. These faults may be potential earthquake areas. For three years (2009–2012), two red wood ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), have been monitored 24/7 by high-resolution cameras with both a color and an infrared sensor. Early results show that ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants’ behavior hours before the earthquake: the nocturnal rest phase and daily activity are suppressed, and standard daily routine does not resume until the next day. At present, an automated image evaluation routine is being applied to the more than 45,000 hours of video streams. Based on this automated approach, a statistical analysis of

  1. Scoliosis screening results of primary school students (11-15 years old group) in the west side of Istanbul.

    PubMed

    Çolak, Tuğba Kuru; Apti, Adnan; Dereli, E Elçin; Özdinçler, Arzu Razak; Çolak, İlker

    2015-09-01

    [Purpose] The present study aimed to find out the scoliosis prevalence 11-15 years old children and to create awareness about scoliosis. [Subjects and Methods] All of the children were assessed using the Adams Forward Bendings Test and a scoliometer. Sagittal plane changes such as kyphosis, lordosis, hypokyphosis, hypolordosis and anterior head tilt were screened. Children with trunk rotation angles (ATR) of 4 degrees or more were suspected of having scoliosis, and were evaluated for a second time for gibbosity height, arm-trunk distance, and ATR. [Results] A total of 2,207 children were screened and the evaluation revealed there were 11 girls (0.49%) with a Cobb angle of 10 degrees and more. The maximum Cobb angle was 43° (right thoracic-left lumbar) and the maximum ATR was 12°. Two children had kyphosis and lordosis, and one had hypokyphosis and was diagnosed as having idiopathic scoliosis. [Conclusion] Families should regularly check their children, even if they are not diagnosed as having scoliosis in school screenings. It is our opinion that our study increased the awareness of the families about scoliosis by screening, brochures and posters. In the future, if school screenings were performed as a routine procedure and scoliotic students were followed over the long term, the actual effectiveness of screening would be able to be detected. PMID:26504296

  2. Reproducibility of estradiol and testosterone levels in postmenopausal women over 5 years: results from the breakthrough generations study.

    PubMed

    Jones, Michael E; Schoemaker, Minouk J; Rae, Megan; Folkerd, Elizabeth J; Dowsett, Mitch; Ashworth, Alan; Swerdlow, Anthony J

    2014-05-01

    Prospective cohort studies examining sex hormones in relation to cancer risk have generally collected blood samples at 1 time point, with an assumption that hormone levels measured in these samples will be reliable markers of true levels at other times. In postmenopausal women, body fat is a major source of estradiol; therefore, changes in adiposity may affect the correlation of single measurements to more relevant long-term averages. To estimate the intraclass correlation coefficient (ICC) for estradiol and testosterone, we collected repeat blood samples from 119 postmenopausal women (average age = 59.4 (standard deviation, 4.7) years) from the United Kingdom during 2004-2005 and again during 2010-2011. The ICCs (adjusted for assay variation) were 0.73 (95% confidence interval: 0.63, 0.82) for total estradiol and 0.59 (95% confidence interval: 0.47, 0.72) for total testosterone. The ICCs were 3%-5% larger after adjustment for change in body mass index (weight (kg)/height (m)(2)) or leptin, which are 2 markers of change in adiposity. There was no increase in ICCs after adjustment for change in age, alcohol consumption, smoking, exercise, time between waking and blood collection, or season. The results suggest that other factors account for within-woman variation in these sex hormones. PMID:24685533

  3. Results from a 3-year deficit irrigation experiment with drip-irrigated maize to improve water productivity

    NASA Astrophysics Data System (ADS)

    Kloss, Sebastian; Schütze, Niels; Grundmann, Jens

    2013-04-01

    Water for irrigation farming is severely limited in arid and semi-arid regions, hence reliable and robust strategies are needed that allow to use the available resources efficiently. Controlled deficit irrigation (DI) is one strategy that can help to use water in an effective way while still ensuring considerable yields from harvest. It needs precise irrigation control however where sensors are used to determine when to irrigate. Therefore, thresholds that trigger irrigation need to be chosen carefully. An irrigation experiment with drip-irrigated maize was conducted in three consecutive years (2010-2012) where different controlled DI strategies were tested. The experiments took place in a greenhouse at TU München in Freising, Germany, and comprised treatments with constant and varying irrigation thresholds throughout the growing season, which were compared to fully irrigated reference treatments. Thresholds were determined in soil tension as it is closely related to the working principle behind plant transpiration and treatments evaluated with regard to their water productivity (WP - yield over applied irrigation water). The irrigation thresholds were determined prior to the experiment by a stochastic simulation-based framework that consisted of a weather generator, the crop growth model Daisy, and an optimization algorithm for finding optimal thresholds under limiting water supply. Achieved results show similar or better WP compared to the reference and generally high WP compared to values from literature which suggests this methodology is a promising approach to improve WP.

  4. Initial Key Results from the NSAC Subcommittee Survey on Nuclear Science PhDs 5-10 Years Later

    NASA Astrophysics Data System (ADS)

    Cerny, Joseph

    2004-05-01

    As a component of a study for the Nuclear Science Advisory Committee which has been asked, in part, to document the effectiveness of the current education in nuclear science, a web-based survey is being conducted by a Subcommittee on all US nuclear science PhDs who graduated 5 to 10 years ago. The survey questionnaire has six sections: (A) the overall career path from the time one received the PhD until the present and the demographic background; (B) the search for the first job after receiving the PhD; (C) the retrospective evaluation of one's doctoral education and experience; (D) the assessment of the usefulness of the doctoral degree; (E) the intersection of family and career; and (F) recommendations and opinions. Inital results of this survey will be presented, focussing on the doctoral and postdoctoral experience. Responses to two open-ended questions are of particular interest: What advice would you offer to graduate students who are just beginning studies in nuclear science; and what recommendations would you offer doctoral programs in nuclear science today?

  5. Titan's Surface at 2.2-Cm Wavelength: Results and Interpretations through the First Ten Years of Observation By Cassini

    NASA Astrophysics Data System (ADS)

    Janssen, M. A.; Le Gall, A. A.; Hayes, A. G., Jr.; Lopes, R. M. C.; Malaska, M. J.

    2014-12-01

    A comprehensive calibration and mapping of the thermal microwave emission from Titan's surface will be presented, based on radiometric data obtained at 2.2-cm wavelength by the passive radiometer in the Cassini Radar instrument through the nearly ten years following Saturn Orbit Insertion. The data reported were accumulated from Titan passes Ta (October 2004) through T98 (February 2014) and now incorporate emission from all of Titan's surface. The mapping will eventually include data at both low and high spatial resolution, while for the present we concentrate on only the low-resolution data that provide thermal polarization. These data are sufficient to examine not only surface effective dielectric constant but seasonal and diurnal surface temperature variations, which we compare with current CIRS results. The map of effective dielectric constant allows us to explore possible regional variations in surface properties and composition. Finally, these data allow us to understand the nature and magnitude of systematic errors in the map-making process, essential to interpreting both the present maps and the forthcoming high-resolution maps based on these. This work was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration.

  6. One-year results from cryopreserved mitral allograft transplantation into the tricuspid position in a sheep experimental model.

    PubMed

    Mokracek, A; Canadyova, J; Simunkova, Z; Fiala, R; Hmirak, M; Sulda, M; Burkert, J; Tintera, J; Kobylka, P; Spatenka, J

    2015-01-01

    Mitral allografts are still used only exceptionally in the mitral or tricuspid position. The main indication remains infectious endocarditis of atrioventricular valves for its flexibility and low risk of infection. The aim of our study was to evaluate 1-year results of mitral allografts transplantation into the tricuspid position in a sheep model. Mitral allografts were processed, cryopreserved, and transplanted into the tricuspid position anatomically (Group I - 11 animals) or antianatomically (Group II - 8 animals). All survivors (4 from Group I, and 3 from Group II) were checked at 3, 6, and 12 months by echocardiography with the exception of one survivor from Group II (which was examinated only visually). Examination throughout follow-up included for mitral allograft regurgitation and annuli dilatation. At postmortem, the papillary muscles were healed and firmly anchored to the right ventricular wall in all subjects. Transventricular fixation of the papillary muscles with buttressed sutures was proven to be a stable, reproducible, and safe method for anchoring mitral allograft leaflets. There were no significant differences between the two implantation methods. Annulus support of mitral allografts might be very useful in this type of operation and could prevent annular dilatation. PMID:26047374

  7. Scoliosis screening results of primary school students (11–15 years old group) in the west side of Istanbul

    PubMed Central

    Çolak, Tuğba Kuru; Apti, Adnan; Dereli, E.Elçin; Özdinçler, Arzu Razak; Çolak, İlker

    2015-01-01

    [Purpose] The present study aimed to find out the scoliosis prevalence 11–15 years old children and to create awareness about scoliosis. [Subjects and Methods] All of the children were assessed using the Adams Forward Bendings Test and a scoliometer. Sagittal plane changes such as kyphosis, lordosis, hypokyphosis, hypolordosis and anterior head tilt were screened. Children with trunk rotation angles (ATR) of 4 degrees or more were suspected of having scoliosis, and were evaluated for a second time for gibbosity height, arm-trunk distance, and ATR. [Results] A total of 2,207 children were screened and the evaluation revealed there were 11 girls (0.49%) with a Cobb angle of 10 degrees and more. The maximum Cobb angle was 43° (right thoracic-left lumbar) and the maximum ATR was 12°. Two children had kyphosis and lordosis, and one had hypokyphosis and was diagnosed as having idiopathic scoliosis. [Conclusion] Families should regularly check their children, even if they are not diagnosed as having scoliosis in school screenings. It is our opinion that our study increased the awareness of the families about scoliosis by screening, brochures and posters. In the future, if school screenings were performed as a routine procedure and scoliotic students were followed over the long term, the actual effectiveness of screening would be able to be detected. PMID:26504296

  8. Early Results of Three-Year Monitoring of Red Wood Ants' Behavioral Changes and Their Possible Correlation with Earthquake Events.

    PubMed

    Berberich, Gabriele; Berberich, Martin; Grumpe, Arne; Wöhler, Christian; Schreiber, Ulrich

    2013-01-01

    Short-term earthquake predictions with an advance warning of several hours or days are currently not possible due to both incomplete understanding of the complex tectonic processes and inadequate observations. Abnormal animal behaviors before earthquakes have been reported previously, but create problems in monitoring and reliability. The situation is different with red wood ants (RWA; Formica rufa-group (Hymenoptera: Formicidae)). They have stationary mounds on tectonically active, gas-bearing fault systems. These faults may be potential earthquake areas. For three years (2009-2012), two red wood ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), have been monitored 24/7 by high-resolution cameras with both a color and an infrared sensor. Early results show that ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants' behavior hours before the earthquake: the nocturnal rest phase and daily activity are suppressed, and standard daily routine does not resume until the next day. At present, an automated image evaluation routine is being applied to the more than 45,000 hours of video streams. Based on this automated approach, a statistical analysis of the ants' behavior will be carried out. In addition, other parameters (climate, geotectonic and biological), which may influence behavior, will be included in the analysis. PMID:26487310

  9. Real-driving emissions from cars and light commercial vehicles - Results from 13 years remote sensing at Zurich/CH

    NASA Astrophysics Data System (ADS)

    Chen, Yuche; Borken-Kleefeld, Jens

    2014-05-01

    We report on long-term remote sensing measurements of light duty vehicle emissions at one site close to Zurich/Switzerland. The time series of annual measurements at the same site between 2000 and 2012, the same season, and virtually the same instrument is unique, probably worldwide. We analyze the development of unit exhaust emissions from model years 1985 until 2012, covering all five Euro emission limit stages in force. NOx emissions from both diesel cars and light commercial vehicles have actually increased in real-driving over time although emission limits have been progressively tightened. This behavior is explained mostly by a significant discrepancy between engine conditions during real-driving and the homologation test procedure. This discrepancy is not important for the other pollutants or for gasoline light duty vehicles, for which the emission control equipment is found working over a wide range of engine conditions. Our results confirm emission factors from the latest HBEFA model when deterioration and engine load are accounted for. Recent remote sensing measurements of diesel cars and light commercial vehicles in London are at the same or higher levels. However, given that engine load is much lower in London, this coincidence is rather puzzling. A key uncertainty is the amount of primary NO2 in the exhaust, and potential systematic differences between dominant brands in European countries. Both needs further investigation.

  10. Radical mastectomy versus radical mastectomy plus internal mammary dissection. Five-year results of an international cooperative study.

    PubMed

    Lacour, J; Bucalossi, P; Cacers, E; Jacobelli, G; Koszarowski, T; Le, M; Rumeau-Rouquette, C; Veronesi, U

    1976-01-01

    From 1963 to 1968, the international group collected 1580 cases of breast cancer, randomized into two therapeutic groups: radical mastectomy and extended mastectomy. The data were processed on the UNIVAC 1107 computer of the I.N.S.E.R.M. Computing Center. No significant difference was observed between the two groups in the overall five-year survival rate. However, a more detailed analysis, according to certain prognostic features, showed that extended mastectomy improved the results in one subgroup: cancers of inner or medial quadrants, axillary N+. Within this group the difference was highly significant for a smaller subgroup (190 patients) including only tumors T1 and T2. In conclusion, there is no indication for extended mastectomy in any cancers of the outer quadrants or in those of the inner or medial quadrants without axillary involvement. A limited indication for extended mastectomy may be provisionally retained for T1 and T2 cancers of the inner or medial quadrants with axillary involvement. PMID:1247957

  11. SU-E-I-90: Medical Physicists' Implication in Diagnostic CT in Switzerland: Results of After One Year of Experience

    SciTech Connect

    Ryckx, N.; Elandoy, C.; Bize, J.; Verdun, F.R.

    2014-06-01

    Purpose: Since January 1st 2008, the Swiss ordinance on radiation protection requires the involvement of a medical physicist to support the optimization process of medical imaging techniques using ionizing radiation. After a long process of implementation, this requirement is satisfied all over the country since the beginning of 2013. The goal of this contribution is to summarize the main results obtained in this first year of experience in CT. Methods: We assessed the output and clinical use of 45 CT units using a three-pronged approach. First, we assessed the output of the device (CTDIvol, primary beam collimation and HU in water at different tube tensions). Secondly, we characterized the local chest and abdomen acquisition and reconstruction protocols using the Catphan 600 phantom. Lastly, we assessed the clinical use of the machine by analyzing an extract of a dozen clinical examinations per unit. Results: 9 out of 45 units had incorrect collimator settings, e.g. 4mm instead of 1mm. We witnessed also a large spread in reconstruction parameters, especially for reconstructed slice thickness, thus showing notable variations in low contrast detectability performances. Clinical practice is also clearly spread out. For example, estimated patient effective dose per abdomen examination lies at 18.7+/−12.7mSv (min: 2.0mSv — max: 112.0mSv). Chest and brain scans have a narrower dispersion, but patient effective dose is also spread by about a factor of 10 to 20. Conclusion: The spread in clinical practice being fairly large, it appears of crucial importance to collaborate more closely with radiologists and technologists to assess it. The lack of statistical precision will imply that we analyze clinical practice according to a specific medical demand rather than an anatomical region. Furthermore, low contrast sensitivity (LCD) being a crucial parameter, an objective method using a model observer will be used to assess LCD.

  12. Retinal nerve fiber layer thickness changes in obstructive sleep apnea syndrome: one year follow-up results

    PubMed Central

    Zengin, Mehmet Ozgur; Tuncer, Ibrahim; Karahan, Eyyup

    2014-01-01

    AIM To investigate the retinal nerve fiber layer (RNFL) thickness changes in patients with obstructive sleep apnea syndrome (OSAS) for one year follow-up. To discuss the possibility of detecting tendency of glaucoma in this population by using spectral domain optical coherence tomography (3D-OCT-2000 Spectral domain). METHODS After polysomnographic study, all subjects (64 OSAS patients and 40 controls) underwent detailed ophthalmological examination. After these examinations, patients with glaucoma and patients who had ophthalmological and/or systemic disease were excluded from the study. Totally, 20 patients in OSAS group and five patients in controls were excluded from the study in the first examination and follow-up period. The RNFL thickness was assessed with OCT. Forty-four OSAS patients and 35 control subjects were followed up 12mo. RNFL thickness change and OSAS patients were evaluated for severity of disease by Apnea-Hypopnea Index (AHI). RESULTS Forty-four OSAS patients and 35 controls were enrolled in the study. Statistically significance was found between OSAS patients and controls at the 12th mo. Average RNFL thickness was found to be significantly lower in last measurements in OSAS patients when compared with first measurements and control subjects (P<0.001, 0.002, respectively). There was a statistically significant correlation among AHI, and RNFL thickness (P<0.05). CONCLUSION The results suggest that the patients with OSAS were related with a proportional decrease in the RNFL thickness. These patients should be followed up regularly for glaucomatous changes. Detecting more RNFL thinning in severe OSAS was important. PMID:25161947

  13. FIRST-YEAR RESULTS OF BROADBAND SPECTROSCOPY OF THE BRIGHTEST FERMI-GBM GAMMA-RAY BURSTS

    SciTech Connect

    Bissaldi, Elisabetta; Von Kienlin, Andreas; Greiner, Jochen; Gruber, David; Lichti, Giselher; Diehl, Roland; Foley, Suzanne; Kouveliotou, Chryssa; Fishman, Gerald J.; Fitzpatrick, Gerard; Gibby, Melissa H.; Giles, Misty M.; Van der Horst, Alexander J.

    2011-06-01

    We present our results of the temporal and spectral analysis of a sample of 52 bright and hard gamma-ray bursts (GRBs) observed with the Fermi Gamma-ray Burst Monitor (GBM) during its first year of operation (2008 July-2009 July).Our sample was selected from a total of 253 GBM GRBs based on the event peak count rate measured between 0.2 and 40 MeV. The final sample comprised of 34 long and 18 short GRBs. These numbers show that the GBM sample contains a much larger fraction of short GRBs than the CGRO/BATSE data set, which we explain as the result of our (different) selection criteria, which favor collection of short, bright GRBs over BATSE. A first by-product of our selection methodology is the determination of a detection threshold from the GBM data alone, above which GRBs most likely will be detected in the MeV/GeV range with the Large Area Telescope on board Fermi. This predictor will be very useful for future multi-wavelength GRB follow-ups with ground- and space-based observatories. Further, we have estimated the burst durations up to 10 MeV and for the first time expanded the duration-energy relationship in the GRB light curves to high energies. We confirm that GRB durations decline with energy as a power law with index approximately -0.4, as was found earlier with the BATSE data and we also notice evidence of a possible cutoff or break at higher energies. Finally, we performed time-integrated spectral analysis of all 52 bursts and compared their spectral parameters with those obtained with the larger data sample of the BATSE data. We find that the two parameter data sets are similar and confirm that short GRBs are in general harder than longer ones.

  14. First-year Results of Broadband Spectroscopy of the Brightest Fermi-GBM Gamma-Ray Bursts

    NASA Astrophysics Data System (ADS)

    Bissaldi, Elisabetta; von Kienlin, Andreas; Kouveliotou, Chryssa; Briggs, Michael S.; Connaughton, Valerie; Greiner, Jochen; Gruber, David; Lichti, Giselher; Bhat, P. N.; Burgess, Michael; Chaplin, Vandiver; Diehl, Roland; Fishman, Gerald J.; Fitzpatrick, Gerard; Foley, Suzanne; Gibby, Melissa H.; Giles, Misty M.; Goldstein, Adam; Guiriec, Sylvain; van der Horst, Alexander J.; Kippen, R. Marc; Lin, Lin; McBreen, Sheila; Meegan, Charles A.; Paciesas, William S.; Preece, Robert D.; Rau, Arne; Tierney, Dave; Wilson-Hodge, Colleen

    2011-06-01

    We present our results of the temporal and spectral analysis of a sample of 52 bright and hard gamma-ray bursts (GRBs) observed with the Fermi Gamma-ray Burst Monitor (GBM) during its first year of operation (2008 July-2009 July).Our sample was selected from a total of 253 GBM GRBs based on the event peak count rate measured between 0.2 and 40 MeV. The final sample comprised of 34 long and 18 short GRBs. These numbers show that the GBM sample contains a much larger fraction of short GRBs than the CGRO/BATSE data set, which we explain as the result of our (different) selection criteria, which favor collection of short, bright GRBs over BATSE. A first by-product of our selection methodology is the determination of a detection threshold from the GBM data alone, above which GRBs most likely will be detected in the MeV/GeV range with the Large Area Telescope on board Fermi. This predictor will be very useful for future multi-wavelength GRB follow-ups with ground- and space-based observatories. Further, we have estimated the burst durations up to 10 MeV and for the first time expanded the duration-energy relationship in the GRB light curves to high energies. We confirm that GRB durations decline with energy as a power law with index approximately -0.4, as was found earlier with the BATSE data and we also notice evidence of a possible cutoff or break at higher energies. Finally, we performed time-integrated spectral analysis of all 52 bursts and compared their spectral parameters with those obtained with the larger data sample of the BATSE data. We find that the two parameter data sets are similar and confirm that short GRBs are in general harder than longer ones.

  15. Diabetes Nurse Case Management and Motivational Interviewing for Change (DYNAMIC): Results of a 2-year Randomized Controlled Pragmatic Trial

    PubMed Central

    Gabbay, Robert A.; Añel-Tiangco, Raquel M.; Dellasega, Cheryl; Mauger, David T.; Adelman, Alan; Van Horn, Deborah H.A.

    2013-01-01

    Objective To determine if the addition of nurse case managers (NCMs) trained in motivational interviewing (MI) to usual care would result in improved outcomes in high risk type 2 diabetes patients. Methods A 2-year randomized controlled pragmatic trial randomized 545 patients to usual care control (n=313) or those who received the intervention (n= 232) with additional practice embedded NCM care, including MI-guided behavior change counseling. NCMs received intensive MI training with ongoing fidelity assessment. Results Systolic BP was better in the intervention group (131±15.9 vs. 135±18.2, p < 0.05). HbA1c, LDL, and diastolic BP improved in both groups: HbA1c (control group 9.1% to 8.0%, intervention group 8.8% to 7.8%), LDL (control group 127 to 100 mg/dL, intervention group 128 to 102 mg/dL), diastolic BP (control group 78 to 74 mm Hg, intervention group 80 to 74 mm Hg). Depression symptom scores were better in the intervention group. The reduction in diabetes-related distress approached statistical significance. Conclusions NCMs and MI improved systolic BP and complications screening. The large decrease in HbA1C and LDL in the control group may have obscured any further intervention effect. Although nurses prompted providers for medication titration, strategies to reduce provider clinical inertia might also be needed. Significant findings of the study In patients with type 2 diabetes, an intervention with nurse case management and motivational interviewing improves systolic blood pressure, depression, and screening for complications. What this study adds First study to look at the benefit of the addition of motivational interviewing to nurse case management in the care of the high-risk adult with type 2 diabetes. Particular attention was given to ensuring fidelity to the motivational interviewing approach. PMID:23368423

  16. Modelling 50,000 Years of Landscape Evolution in the Upper Thames Valley, UK: Preliminary Results from PARALLEM

    NASA Astrophysics Data System (ADS)

    Wainwright, J.; Maddy, D.; McGough, S.; Trueman, A.; Briant, R. M.; Stemerdink, C.

    2014-12-01

    The last glacial-interglacial fluvial archive of the Upper Thames catchment, UK has received much attention over the past 50 years. Extensive exposures within the Pleistocene sequence have yielded a vast array of field observations, constrained by a substantive, but still inadequate, geochronological dataset. This catchment was not glaciated during this period, lying well beyond the Devensian (MIS2) ice margin, and thus landscape morphological evolution progressed largely in response to variation in fluvial and slope processes forced primarily by climate-driven hydrological and vegetation change. Furthermore, there is no evidence to support any significant tectonic-driven change, albeit fluvial system evolution progressed within the context of long-term regional uplift. The relative simplicity of process interactions within this catchment over the timeframe of interest, taken together with its comprehensive sedimentary record, makes the Upper Thames archive a good candidate for comparison with landscape evolution model outputs. In this paper we present a 'first look' at the performance of PARALLEM, a new, parallel-coded, landscape evolution model, with results presented from an initial 50,000-year simulation. In this instance PARALLEM was deployed in annual, steady-flow mode. The model is driven by changing precipitation and temperatures. A pre-determined precipitation input data series was used, based upon a simple transfer function which utilises an up-sampled North Atlantic SST record, together with a modified temperature series based upon palaeoecological data. PARALLEM explicitly models mass-movement processes (i.e. creep, gelifluction) and surface erosion by flowing water (i.e. diffuse and concentrated erosion) using formulae derived from empirical modern-day process data. The model also deploys a simple logistic growth/die-back model for vegetation driven by hydrological and temperature change. Sediment transport is modelled using a modified transport

  17. Initial vs Recurrent Training for Skilled Trades in Israel--Results of a 7-Year Follow-Up Study.

    ERIC Educational Resources Information Center

    Ziderman, Adrian

    1987-01-01

    The earnings of former trainees for the skilled trades in Israel were monitored over a seven-year period. While no significant differences were found between graduates of one-year adult training courses and similar programs for teenagers, postponement of training until the 20's is not a paying proposition. Contains one figure, two tables, and 15…

  18. Estimating winter cover crop nitrogen uptake with satellite imagery:four years of results from the Choptank River

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Choptank River Watershed Conservation Effects Assessment Project (CEAP) has now accumulated a four-year set of quarterly SPOT satellite images taken over the Eastern Shore of the Chesapeake Bay watershed. Imagery collected in December and March of each year were used to estimate the productivity...

  19. Eight-Year Follow-Up Results of an Adolescent Smoking Prevention Program: The North Karelia Youth Project.

    ERIC Educational Resources Information Center

    Vartiainen, Erkki; And Others

    1990-01-01

    Discusses an 8-year follow-up study to a smoking prevention program for 13- to 15- year-old students, who were taught the skills to resist pressures to start smoking. Consistent evidence of preventive effects was found among those students who had been non-smokers when the program began. (Author/JS)

  20. Trajectories of Heroin Addiction: Growth Mixture Modeling Results Based on a 33-Year Follow-Up Study

    ERIC Educational Resources Information Center

    Hser, Yih-Ing; Huang, David; Chou, Chih-Ping; Anglin, M. Douglas

    2007-01-01

    This study investigates trajectories of heroin use and subsequent consequences in a sample of 471 male heroin addicts who were admitted to the California Civil Addict Program in 1964-1965 and followed over 33 years. Applying a two-part growth mixture modeling strategy to heroin use level during the first 16 years of the addiction careers since…

  1. COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar": first-year activities and results

    NASA Astrophysics Data System (ADS)

    Pajewski, Lara; Benedetto, Andrea; Loizos, Andreas; Slob, Evert; Tosti, Fabio

    2014-05-01

    This work aims at presenting the first-year activities and results of COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar". This Action was launched in April 2013 and will last four years. The principal aim of COST Action TU1208 is to exchange and increase scientific-technical knowledge and experience of GPR techniques in civil engineering, whilst simultaneously promoting throughout Europe the effective use of this safe and non-destructive technique in the monitoring of infrastructures and structures. Moreover, the Action is oriented to the following specific objectives and expected deliverables: (i) coordinating European scientists to highlight problems, merits and limits of current GPR systems; (ii) developing innovative protocols and guidelines, which will be published in a handbook and constitute a basis for European standards, for an effective GPR application in civil- engineering tasks; safety, economic and financial criteria will be integrated within the protocols; (iii) integrating competences for the improvement and merging of electromagnetic scattering techniques and of data- processing techniques; this will lead to a novel freeware tool for the localization of buried objects, shape-reconstruction and estimation of geophysical parameters useful for civil engineering needs; (iv) networking for the design, realization and optimization of innovative GPR equipment; (v) comparing GPR with different NDT techniques, such as ultrasonic, radiographic, liquid-penetrant, magnetic-particle, acoustic-emission and eddy-current testing; (vi) comparing GPR technology and methodology used in civil engineering with those used in other fields; (vii) promotion of a more widespread, advanced and efficient use of GPR in civil engineering; and (viii) organization of a high-level modular training program for GPR European users. Four Working Groups (WGs) carry out the research activities. The first WG

  2. Long-Term Protection against Diphtheria in the Netherlands after 50 Years of Vaccination: Results from a Seroepidemiological Study

    PubMed Central

    Swart, E. M.; van Gageldonk, P. G. M.; de Melker, H. E.; van der Klis, F. R.; Berbers, G. A. M.; Mollema, L.

    2016-01-01

    Background and Aims To evaluate the National Immunisation Programme (NIP) a population-based cross-sectional seroepidemiological study was performed in the Netherlands. We assessed diphtheria antitoxin levels in the general Dutch population and in low vaccination coverage (LVC) areas where a relatively high proportion of orthodox Protestants live who decline vaccination based on religious grounds. Results were compared with a nationwide seroepidemiological study performed 11 years earlier. Methods In 2006/2007 a national serum bank was established. Blood samples were tested for diphtheria antitoxin IgG concentrations using a multiplex immunoassay for 6383 participants from the national sample (NS) and 1518 participants from LVC municipalities. A cut-off above 0.01 international units per ml (IU/ml) was used as minimum protective level. Results In the NS 91% of the population had antibody levels above 0.01 IU/ml compared to 88% in the 1995/1996 serosurvey (p<0.05). On average, 82% (vs. 78% in the 1995/1996 serosurvey, p<0.05) of individuals from the NS born before introduction of diphtheria vaccination in the NIP and 46% (vs. 37% in the 1995/1996 serosurvey, p = 0.11) of orthodox Protestants living in LVC areas had antibody levels above 0.01 IU/ml. Linear regression analysis among fully immunized individuals (six vaccinations) without evidence of revaccination indicated a continuous decline in antibodies in both serosurveys, but geometric mean antibodies remained well above 0.01 IU/ml in all age groups. Conclusions The NIP provides long-term protection against diphtheria, although antibody levels decline after vaccination. As a result of natural waning immunity, a substantial proportion of individuals born before introduction of diphtheria vaccination in the NIP lack adequate levels of diphtheria antibodies. Susceptibility due to lack of vaccination is highest among strictly orthodox Protestants. The potential risk of spread of diphtheria within the geographically

  3. SU-C-BRD-01: Multi-Centre Collaborative Quality Assurance Program for IMRT Planning and Delivery: Year 3 Results

    SciTech Connect

    McNiven, A; Jaffray, D; Letourneau, D

    2015-06-15

    Purpose: A multi-centre quality assurance program was developed to enable quality improvement by coupling measurement of intensity modulated radiotherapy (IMRT) planning and delivery performance for site-specific planning exercises with diagnostic testing. The third year of the program specifically assessed the quality of spine stereotactic body radiotherapy (SBRT) planning and delivery amongst the participating centres. Methods: A spine SBRT planning exercise (24 Gy in 2 fractions) was created and completed by participants prior to an on-site visit. The delivery portion of the on-site visit included spine SBRT plan delivery and diagnostic testing, which included portal image acquisition for quantification of phantom positioning error and multi-leaf collimator (MLC) calibration accuracy. The measured dose was compared to that calculated in the treatment planning system (TPS) using 3%/2mm composite analysis and 3%/3mm gamma analysis. Results: Fourteen institutions participated, creating 17 spine SBRT plans (15 VMAT and 2 IMRT). Three different TPS, two beam energies (6 MV and 6 MV FFF), and four MLC designs from two linac vendors were tested. Large variation in total monitor units (MU) per plan (2494–6462 MU) and dose-volume parameters was observed. The maximum point dose in the plans ranged from 116–149% and was dependent upon the TPS used. Pass rates for measured to planned dose comparison ranged from 89.4–100% and 97.3–100% for 3%/2mm and 3%/3mm criteria respectively. The largest measured MLC error did Result in one of the poorer pass rates. No direct correlation between phantom positioning error and pass rates overall. Conclusion: Significant differences were observed in the planning exercise for some plan and dose-volume parameters based on the TPS used. Standard evaluation criteria showed good agreement between planned and measured dose for all participants, however on an individual plan basis, diagnostic tests were able to identify contributing

  4. First Results of 3 Year Monitoring of Red Wood Ants' Behavioural Changes and Their Possible Correlation with Earthquake Events

    NASA Astrophysics Data System (ADS)

    Berberich, Gabriele; Berberich, Martin; Grumpe, Arne; Wöhler, Christian; Schreiber, Ulrich

    2013-04-01

    Short-term earthquake predictions with an advance warning of several hours or days can currently not be performed reliably and remain limited to only a few minutes before the event. Abnormal animal behaviours prior to earthquakes have been reported previously but their detection creates problems in monitoring and reliability. A different situation is encountered for red wood ants (RWA; Formica rufa-group (Hymenoptera: Formicidae). They have stationary nest sites on tectonically active, gas-bearing fault systems. These faults may be potential earthquake areas and are simultaneously information channels deeply reaching into the crust. A particular advantage of monitoring RWA is their high sensitivity to environmental changes. Besides an evolutionarily developed extremely strong temperature sensitivity of 0.25 K, they have chemoreceptors for the detection of CO2 concentrations and a sensitivity for electromagnetic fields. Changes of the electromagnetic field are discussed or short-lived "thermal anomalies" are reported as trigger mechanisms for bioanomalies of impending earthquakes. For 3 years, we have monitored two Red Wood Ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), 24/7 by high-resolution cameras equipped with a colour and infrared sensor. In the Neuwied Basin, an average of about 100 earthquakes per year with magnitudes up to M 3.9 occur located on different tectonic fault regimes (strike-slip faults and/or normal or thrust faults). The RWA mounds are located on two different fault regimes approximately 30 km apart. First results show that the ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants' behaviour hours before the earthquake event: The nocturnal rest phase and daily activity are suppressed, and standard daily routine is continued not before the next day. Additional parameters that might have an effect on the ants' daily routine

  5. Stability of the Earth Radiation Budget Experiment scanner results for the first two years of multiple-satellite operation

    NASA Technical Reports Server (NTRS)

    Staylor, W. Frank

    1993-01-01

    Clear-sky albedos and outgoing longwave radiation (OLR) determined from Earth Radiation Budget Experiment (ERBE) scanners on board the earth radiation budget satellite and NOAA-9 spacecraft were analyzed for three target sites for the months February 1985-January 1987. The targets were oceans, deserts, and a multiscene site covering half the earth's surface. Year-to-year ratios of the monthly albedos and OLR were within the 0.98-1.02 range with a standard error of about 1%. The data indicate that ERBE scanner measurements were stable to within a few tenths of a percent for the two-year periods.

  6. French regional surveillance program of carbapenemase-producing Gram-negative bacilli: results from a 2-year period.

    PubMed

    Pantel, A; Boutet-Dubois, A; Jean-Pierre, H; Marchandin, H; Sotto, A; Lavigne, J-P

    2014-12-01

    In February 2011, the CARB-LR group was created as a sentinel laboratory-based surveillance network to control the emergence of carbapenem-resistant Gram-negative bacilli (CR GNB) in a French Southern Region. We report the epidemiological results of a 2-year study. All the Gram-negative bacilli isolates detected in the different labs (hospital and community settings) of a French Southern Region and with reduced susceptibility to ertapenem and/or imipenem were characterised with regard to antibiotic resistance, bla genes content, repetitive sequence-based polymerase chain reaction (rep-PCR) profiles and multilocus sequence typing (MLST). A total of 221 strains were analysed. Acinetobacter baumannii was the most prevalent carbapenemase-producing bacteria, with a majority of OXA-23 producers (n = 37). One isolate co-produced OXA-23 and OXA-58 enzymes. Klebsiella pneumoniae was the most frequent carbapenemase-producing Enterobacteriaceae (CPE) (OXA-48 producer: n = 29, KPC producer: n = 1), followed by Escherichia coli (OXA-48 producer: n = 8, KPC producer: n = 1) and Enterobacter cloacae (OXA-48 producer, n = 1). One isolate of Pseudomonas aeruginosa produced a VIM-1 carbapenemase. A clonal diversity of carbapenemase-producing K. pneumoniae and E. coli was noted with different MLSTs. On the other hand, almost all OXA-23-producing A. baumannii strains belonged to the widespread ST2/international clone II. The link between the detection of CR GNB and a foreign country was less obvious, suggesting the beginning of a local cross-transmission. The number of CR GNB cases in our French Southern Region has sharply increased very recently due to the diffusion of OXA-48 producers. PMID:25037867

  7. Rheumatoid Arthritis and Mortality Among Women During 36 Years of Prospective Follow-Up: Results From the Nurses’ Health Study

    PubMed Central

    SPARKS, JEFFREY A.; CHANG, SHUN-CHIAO; LIAO, KATHERINE P.; LU, BING; FINE, ALEXANDER R.; SOLOMON, DANIEL H.; COSTENBADER, KAREN H.; KARLSON, ELIZABETH W.

    2016-01-01

    Objective To evaluate rheumatoid arthritis (RA) and mortality risk among women followed prospectively in the Nurses’ Health Study (NHS). Methods We analyzed 119,209 women in the NHS who reported no connective tissue disease at enrollment in 1976. Comorbidity and lifestyle data were collected through biennial questionnaires. Incident RA cases were validated by medical records review. Cause of death was determined by death certificate and medical records review. Cox regression models estimated hazard ratios (HRs) and 95% confidence intervals (95% CIs) for all-cause, cardiovascular disease (CVD), cancer, and respiratory disease mortality for women with RA compared to those without RA. Results We validated 964 incident RA cases and identified 28,808 deaths during 36 years of prospective follow-up. Of 307 deaths among women with RA, 80 (26%) were from cancer, 70 (23%) were from CVD, and 44 (14%) were from respiratory causes. Women with RA had increased total mortality (HR 1.40, 95% CI 1.25–1.57) compared to those without RA, independent of mortality risk factors, including smoking. RA was associated with significantly increased respiratory disease mortality (HR 2.06, 95% CI 1.51–2.80) and cardiovascular disease mortality (HR 1.45, 95% CI 1.14–1.83), but not cancer mortality (HR 0.93, 95% CI 0.74–1.15). For women with seropositive RA, respiratory disease mortality was nearly 3-fold higher than among non-RA women (HR 2.67, 95% CI 1.89–3.77). Conclusion Women with RA had significantly increased mortality compared to those without RA. Respiratory disease and cardiovascular disease mortality were both significantly elevated for women with RA. The nearly 3-fold increased relative risk of respiratory disease mortality was observed only for those with seropositive RA. PMID:26473946

  8. Ultrasound-guided foam sclerotherapy of great saphenous vein with 2% polidocanol – one-year follow-up results

    PubMed Central

    Osęka, Marcin; Tworus, Robert; Gałązka, Zbigniew

    2016-01-01

    Introduction Ultrasound-guided foam sclerotherapy (UGFS) of varicose veins is a useful treatment option. It is a relatively safe method in the case of limited, small varicose veins. In theory, a justified concern could be raised that the injection of an active drug into the large superficial venous vessels may potentially cause life-threatening consequences. Aim To assess the safety and efficacy of UGFS using a 2% solution of polidocanol (Aethoxysklerol 2%) in the case of great saphenous vein incompetence. Material and methods Fifty-two patients with great saphenous vein incompetence underwent ultrasound-guided foam sclerotherapy. The efficacy criterion was the elimination of reflux measured ultrasonographically and withdrawal or decrease of complaints: 1 week, and 1, 3, 6 and 12 months after the treatment. Complications of sclerotherapy were reported during follow-up. Results Decrease or withdrawal of complaints of chronic venous insufficiency was reported in 96% of cases (50 patients). Disappearance or decrease of varicose veins was noted in all patients (100%). During examination after 12 months, full success of ultrasound was achieved in 38 (73%) cases, and 11 (21%) patients presented a partial desired effect according to the consensus from Tegernsee. Persistence of reflux longer than 1 s in the treated great saphenous vein was reported in 3 (6%) cases. Serious complications, such as deep vein thrombosis, pulmonary embolism, dyspnea, anaphylaxis, or neurological abnormalities, were not recorded. Conclusions Ultrasound-guided foam sclerotherapy of incompetent great saphenous vein and varicosities with 2% polidocanol was found to be an effective and safe method of treatment during 1 year of observation. However, longer observation is necessary. PMID:27458485

  9. Dietary habits and mortality in 11,000 vegetarians and health conscious people: results of a 17 year follow up.

    PubMed Central

    Key, T. J.; Thorogood, M.; Appleby, P. N.; Burr, M. L.

    1996-01-01

    OBJECTIVE: To investigate the association of dietary habits with mortality in a cohort of vegetarians and other health conscious people. DESIGN: Observational study. SETTING: United Kingdom. SUBJECTS: 4336 men and 6435 women recruited through health food shops, vegetarian societies, and magazines. MAIN OUTCOME MEASURES: Mortality ratios for vegetarianism and for daily versus less than daily consumption of wholemeal bread, bran cereals, nuts or dried fruit, fresh fruit, and raw salad in relation to all cause mortality and mortality from ischaemic heart disease, cerebrovascular disease, all malignant neoplasms, lung cancer, colorectal cancer, and breast cancer. RESULTS: 2064 (19%) subjects smoked, 4627 (43%) were vegetarian, 6699 (62%) ate wholemeal bread daily, 2948 (27%) ate bran cereals daily, 4091 (38%) ate nuts or dried fruit daily, 8304 (77%) ate fresh fruit daily, and 4105 (38%) ate raw salad daily. After a mean of 16.8 years follow up there were 1343 deaths before age 80. Overall the cohort had a mortality about half that of the general population. Within the cohort, daily consumption of fresh fruit was associated with significantly reduced mortality from ischaemic heart disease (rate ratio adjusted for smoking 0.76 (95% confidence interval 0.60 to 0.97)), cerebrovascular disease (0.68 (0.47 to 0.98)), and for all causes combined (0.79 (0.70 to 0.90)). CONCLUSIONS: In this cohort of health conscious individuals, daily consumption of fresh fruit is associated with a reduced mortality from ischaemic heart disease, cerebrovascular disease, and all causes combined. PMID:8842068

  10. Infall motions in massive star-forming regions: results from years 1 and 2 of the MALT90 survey

    NASA Astrophysics Data System (ADS)

    He, Yu-Xin; Zhou, Jian-Jun; Esimbek, Jarken; Ji, Wei-Guang; Wu, Gang; Tang, Xin-Di; Yuan, Ye; Li, Da-Lei; Baan, W. A.

    2015-06-01

    Massive star-forming regions with observed infall motions are good sites for studying the birth of massive stars. In this paper, 405 compact sources have been extracted from the APEX Telescope Large Area Survey of the Galaxy (ATLASGAL) compact sources that also have been observed in the Millimetre Astronomy Legacy Team 90-GHz (MALT90) survey during years 1 and 2. These observations are complemented with Spitzer GLIMPSE/MIPSGAL mid-IR survey data to help classify the elected star-forming clumps into three evolutionary stages: pre-stellar, proto-stellar and UCHII regions. The results suggest that 0.05 g cm-2 is a reliable empirical lower bound for the clump surface densities required for massive-star formation to occur. The optically thick HCO+(1-0) and HNC(1-0) lines, as well as the optically thin N2H+(1-0) line were used to search for infall motions towards these sources. By analysing the asymmetries of the optically thick HCO+(1-0) and HNC(1-0) lines and the mapping observations of HCO+(1-0), a total of 131 reliable infall candidates have been identified. The HCO+(1-0) line shows the highest occurrence of obvious asymmetric features, suggesting that it may be a better infall motion tracer than other lines such as HNC(1-0). The detection rates of infall candidates towards pre-stellar, proto-stellar and UCHII clumps are 0.3452, 0.3861 and 0.2152, respectively. The relatively high detection rate of infall candidates towards UCHII clumps indicates that many UCHII regions are still accreting matter. The peak column densities and masses of the infall candidates, in general, display an increasing trend with progressing evolutionary stages. However, the rough estimates of the mass infall rate show no obvious variation with evolutionary stage.

  11. Evaluating 4 years of atmospheric ammonia (NH3) over Europe using IASI satellite observations and LOTOS-EUROS model results

    NASA Astrophysics Data System (ADS)

    Van Damme, M.; Wichink Kruit, R. J.; Schaap, M.; Clarisse, L.; Clerbaux, C.; Coheur, P.-F.; Dammers, E.; Dolman, A. J.; Erisman, J. W.

    2014-08-01

    Monitoring ammonia (NH3) concentrations on a global to regional scale is a challenge. Due to the limited availability of reliable ground-based measurements, the determination of NH3 distributions generally relies on model calculations. Novel remotely sensed NH3burdens provide valuable insights to complement traditional assessments for clear-sky conditions. This paper presents a first quantitative comparison between Atmospheric Sounding Interferometer (IASI) satellite observations and LOTOS-EUROS model results over Europe and Western Russia. A methodology to account for the variable retrieval sensitivity of the measurements is described. Four years of data (2008-2011) highlight three main agricultural hot spot areas in Europe: the Po Valley, the continental part of Northwestern Europe, and the Ebro Valley. The spatial comparison reveals a good overall agreement of the NH3 distributions not only in these source regions but also over remote areas and over sea when transport is observed. On average, the measured columns exceed the modeled ones, except for a few cases. Large discrepancies over several industrial areas in Eastern Europe and Russia point to underestimated emissions in the underlying inventories. The temporal analysis over the three hot spot areas reveals that the seasonality is well captured by the model when the lower sensitivity of the satellite measurements in the colder months is taken into account. Comparison of the daily time series indicates possible misrepresentations of the timing and magnitude of the emissions. Finally, specific attention to biomass burning events shows that modeled plumes are less spread out than the observed ones. This is confirmed for the 2010 Russian fires with a comparison using in situ observations.

  12. The OmegaWhite Survey for short period variable stars II: An overview of results from the first four years

    NASA Astrophysics Data System (ADS)

    Toma, R.; Ramsay, G.; Macfarlane, S.; Groot, P. J.; Woudt, P. A.; Dhillon, V.; Jeffery, C. S.; Marsh, T.; Nelemans, G.; Steeghs, D.

    2016-08-01

    OmegaWhite is a wide-field, high cadence, synoptic survey targeting fields in the southern Galactic plane, with the aim of discovering short period variable stars. Our strategy is to take a series of 39 s exposures in the g band of a 1 square degree of sky lasting 2 h using the OmegaCAM wide field imager on the VLT Survey Telescope (VST). We give an overview of the initial 4 years of data which covers 134 square degrees and includes 12.3 million light curves. As the fields overlap with the VLT Survey Telescope Hα Photometric Survey of the Galactic plane and Bulge (VPHAS+), we currently have ugriHα photometry for ˜1/3 of our fields. We find that a significant fraction of the light curves have been affected by the diffraction spikes of bright stars sweeping across stars within a few dozen of pixels over the two hour observing time interval due to the alt-az nature of the VST. We select candidate variable stars using a variety of variability statistics, followed by a manual verification stage. We present samples of several classes of short period variables, including: an ultra compact binary, a DQ white dwarf, a compact object with evidence of a 100 min rotation period, three CVs, one eclipsing binary with an 85 min period, a symbiotic binary which shows evidence of a 31 min photometric period, and a large sample of candidate δ Sct type stars including one with a 9.3 min period. Our overall goal is to cover 400 square degrees, and this study indicates we will find many more interesting short period variable stars as a result.

  13. The Catalonia WHO Demonstration Project of Palliative Care: Results at 25 Years (1990-2015).

    PubMed

    Gómez-Batiste, Xavier; Blay, Carles; Martínez-Muñoz, Marisa; Lasmarías, Cristina; Vila, Laura; Espinosa, José; Costa, Xavier; Sánchez-Ferrin, Pau; Bullich, Ingrid; Constante, Carles; Kelley, Ed

    2016-07-01

    In 2015, the World Health Organization (WHO) Demonstration Project on Palliative Care in Catalonia (Spain) celebrated its 25th anniversary. The present report describes the achievements and progress made through this project. Numerous innovations have been made with regard to the palliative care (PC) model, organization, and policy. As the concept of PC has expanded to include individuals with advanced chronic conditions, new needs in diverse domains have been identified. The WHO resolution on "Strengthening of palliative care as a component of comprehensive care throughout the life course," together with other related WHO initiatives, support the development of a person-centered integrated care PC model with universal coverage. The Catalan Department of Health, together with key institutions, developed a new program in the year 2011 to promote comprehensive and integrated PC approach strategies for individuals with advanced chronic conditions. The program included epidemiologic research to describe the population with progressive and life-limiting illnesses. One key outcome was the development of a specific tool (NECPAL CCOMS-ICO(©)) to identify individuals in the community in need of PC. Other innovations to emerge from this project to improve PC provision include the development of the essential needs approach and integrated models across care settings. Several educational and research programs have been undertaken to complement the process. These results illustrate how a PC program can respond and adapt to emerging needs and demands. The success of the PC approach described here supports more widespread adoption by other key care programs, particularly chronic care programs. PMID:27233146

  14. Lymphoma in patients treated with anti-TNF: results of the 3-year prospective French RATIO registry

    PubMed Central

    Mariette, Xavier; Tubach, Florence; Bagheri, Haleh; Bardet, Michel; Berthelot, Jean-Marie; Gaudin, Philippe; Heresbach, Denis; Martin, Antoine; Schaeverbeke, Thierry; Salmon, Dominique; Lemann, Marc; Hermine, Olivier; Raphael, Martine; Ravaud, Philippe

    2010-01-01

    Objective To describe cases of lymphoma associated with anti-TNF therapy, identify risk factors, estimate the incidence and compare risks for different anti-TNF agents. Methods We designed a national prospective registry (RATIO) from 2004 to 2006, for collecting all cases of lymphoma in French patients receiving anti-TNF therapy, whatever the indication. We conducted a case-control analysis including two controls treated with anti-TNF per case and an incidence study of lymphoma with the French population used as reference.. Results We collected 38 cases of lymphoma, 31 non-Hodgkin’s lymphoma (NHL) (26 B-cell and 5 T-cell), 5 Hodgkin’s lymphoma (HL) and 2 Hodgkin’s-like lymphoma. Epstein-Barr virus (EBV) was detected in 2 of 2 Hodgkin’s-like lymphoma, 3 of 5 HL and one NHL. Patients receiving adalimumab or infliximab had a higher risk than those treated with etanercept: SIR = 4.1 (2.3–7.1) and 3.6 (2.3–5.6) versus 0.9 (0.4– 1.8). The exposure to adalimumab or infliximab versus etanercept was an independent risk factor for lymphoma in the case-control study: odds ratio=4.7 (1.3– 17.7) and 4.1 (1.4–12.5), respectively. The sex and age- adjusted incidence rate of lymphoma was 42.1 per 100,000 patient-years. The standardized incidence ratio (SIR) was 2.4 (95% confidence interval [CI] 1.7–3.2). Conclusion Some lymphomas associated with immunosuppression may occur in patients receiving anti TNF therapy, and the risk of lymphoma is higher with monoclonal-antibody therapy than with soluble-receptor therapy. PMID:19828563

  15. The Young Solar Analogs Project. I. Spectroscopic and Photometric Methods and Multi-year Timescale Spectroscopic Results

    NASA Astrophysics Data System (ADS)

    Gray, R. O.; Saken, J. M.; Corbally, C. J.; Briley, M. M.; Lambert, R. A.; Fuller, V. A.; Newsome, I. M.; Seeds, M. F.; Kahvaz, Y.

    2015-12-01

    This is the first in a series of papers presenting methods and results from the Young Solar Analogs Project, which began in 2007. This project monitors both spectroscopically and photometrically a set of 31 young (300-1500 Myr) solar-type stars with the goal of gaining insight into the space environment of the Earth during the period when life first appeared. From our spectroscopic observations we derive the Mount Wilson S chromospheric activity index (SMW), and describe the method we use to transform our instrumental indices to SMW without the need for a color term. We introduce three photospheric indices based on strong absorption features in the blue-violet spectrum—the G-band, the Ca i resonance line, and the Hydrogen-γ line—with the expectation that these indices might prove to be useful in detecting variations in the surface temperatures of active solar-type stars. We also describe our photometric program, and in particular our "Superstar technique" for differential photometry which, instead of relying on a handful of comparison stars, uses the photon flux in the entire star field in the CCD image to derive the program star magnitude. This enables photometric errors on the order of 0.005-0.007 magnitude. We present time series plots of our spectroscopic data for all four indices, and carry out extensive statistical tests on those time series demonstrating the reality of variations on timescales of years in all four indices. We also statistically test for and discover correlations and anti-correlations between the four indices. We discuss the physical basis of those correlations. As it turns out, the "photospheric" indices appear to be most strongly affected by emission in the Paschen continuum. We thus anticipate that these indices may prove to be useful proxies for monitoring emission in the ultraviolet Balmer continuum. Future papers in this series will discuss variability of the program stars on medium (days-months) and short (minutes to hours

  16. Evolution of the concept of Capacity-building, results achieved during the past years and the future

    NASA Astrophysics Data System (ADS)

    Laffaiteur, M.; Camacho, S.

    Capacity-building is one of the key elements for the implementation of space applications programmes, particularly in developing countries. As early as 1982, the work programme of the United Nations Programme on Space Applications was expanded in order to promote education and training by organizing seminars, training courses and workshops in various areas, such as astronomy, telecommunications and Earth observation. In the framework of this Programme, the Office for Outer Space Affairs undertook the initiative, at the beginning of the 1990's, aimed at establishing regional centres for space science and technology education, affiliated to the United Nations and located in developing countries. These centres have started their activities between 1995 and 2000 in Africa, Asia and the Pacific, and Latin America and the Caribbean. The centres are based on the concept that by pooling material and human resources, developing countries can have education and training centres, of an international-level quality. A considerable impetus has been given to capacity-building after the UNISPACE III Conference, in particular in the "Vienna Declaration on Space and Human Development". The necessity to enhance capacity-building through the development of human and budgetary resources, the training of teachers, the exchange of teaching methods, materials and experience and the development of infrastructure and policy regulatories. In the process of the implementation of the recommendations of UNISPACE III, Action Teams led by Governments were established. One of them was exclusively dealing with capacity-building. Its proposals have been reviewed last June by the Committee on the Peaceful Uses of Outer Space (COPUOS) and will be examined, among other reports of Action Teams, by the General Assembly in next October. A lot of work has been done during the past years and have produced very important results. But there is still an important gap in capacity-building between space

  17. High risk of peripheral arterial disease in the United Kingdom: 2-year results of a prospective registry.

    PubMed

    Stansby, Gerard; Mister, Rebecca; Fowkes, Gerry; Roughton, Michael; Nugara, Fiona; Brittenden, Julie; Bradbury, Andrew; Ashley, Simon; Shearman, Cliff; Hannon, Ray; Flather, Marcus

    2011-02-01

    We report a prospective 2-year, multicenter study of patients presenting with intermittent claudication (IC; ankle brachial blood pressure index, ABPI ≤ 0.9). Mean age of the 473 patients enrolled was 68 years, 20% were diabetics, 30% had prior symptomatic coronary heart disease (CHD), 7% had prior stroke, and 39% were current smokers. At baseline, 26.2% of patients had BP ≤ 140/85 mm Hg or lower and at 2 years this figure was 32.5% (P = .01). Current smokers had fallen to 27% (from 39%) at 2 years (P < .001). Use of antiplatelet agents, statins, and angiotensin converting enzyme inhibitors increased significantly during the course of the study as did claudication distance. Death and the composite of death, stroke or myocardial infarction (MI), occurred in 8.4% and 11.6% of patients, respectively. Prognosis was worse in patients with prior history of CHD, older age, those with diabetes and a lower ABPI. PMID:21220371

  18. Increasing Independence through Technology: The Views of Older Consumers with Disabilities and Their Caregivers. Consumer Needs Assessment Project Year 3: Results of the Third Year of a Five Year Study.

    ERIC Educational Resources Information Center

    Ward, Carolyn

    The goal of this third year of an ongoing 5-year study was to identify and evaluate the diverse technology and product needs of persons with functional limitations, from users' perspectives. This qualitative research study involved 14 focus groups representing 4 different categories of people; those included persons 50 years and older with sensory…

  19. Deep Vadose Zone Treatability Test for the Hanford Central Plateau. Interim Post-Desiccation Monitoring Results, Fiscal Year 2015

    SciTech Connect

    Truex, Michael J.; Strickland, Christopher E.; Oostrom, Martinus; Johnson, Christian D.; Tartakovsky, Guzel D.; Johnson, Timothy C.; Clayton, Ray E.; Chronister, Glen B.

    2015-09-01

    A field test of desiccation is being conducted as an element of the Deep Vadose Zone Treatability Test Program. The active desiccation portion of the test has been completed. Monitoring data have been collected at the field test site during the post-desiccation period and are reported herein. This is an interim data summary report that includes about 4 years of post-desiccation monitoring data. The DOE field test plan proscribes a total of 5 years of post-desiccation monitoring.

  20. Thermal regime and potential bedrock weathering in alpine rockwalls of Austria: Results from eight years of monitoring (2006-2014)

    NASA Astrophysics Data System (ADS)

    Kellerer-Pirklbauer, Andreas; Wecht, Matthias

    2015-04-01

    FTC and eFTC was lowest during the hydrological year 06/07 (snow poor and warm winter) whereas highest in 11/12 (snow poor but rather cool winter). In contrast, results are completely different at two substantially higher-elevated but also north-exposed RTS (2639 and 2700 m asl) with highest FTC values in 06/07 and lowest in 11/12. Furthermore, at the two flat bedrock sites (at 2603 and 2650 m asl) the number of FTC and eFTC was highest in 06/07 related to the thin and short winter snow cover. The latter observation suggests that supposed warmer and snow-poor winters in the future will enhance diurnal freeze-thaw cycles and the intensity of near-surface physical weathering in the bedrock of the Austrian Alps. This seems to be feasible at least for elevations above c.2600 m asl.

  1. Land use mix and five-year mortality in later life: Results from the Cognitive Function and Ageing Study

    PubMed Central

    Wu, Yu-Tzu; Prina, A. Matthew; Jones, Andy; Barnes, Linda E.; Matthews, Fiona E.; Brayne, Carol; MRC CFAS

    2016-01-01

    This study explores the potential modifying effect of age and mediation effect of co-morbidity on the association between land use mix, a measure of neighbourhood walkability, and five-year mortality among the 2424 individuals participating in the year-10 follow-up of the Cognitive Function and Ageing Study in England. Postcodes of participants were mapped onto Lower-layer Super Output Areas, a small area level geographical unit in the UK, and linked to Generalised Land Use data. Cox regression models were fitted to investigate the association. For the younger older age group (75–79 years), the effect of high land use mix on an elevated risk of mortality was mediated by co-morbidity. For older old age groups (80–84, 85+ years), a higher land use mix was directly associated with a 10% lower risk of five-year mortality. The findings suggest differential impacts of land use mix on the health of the younger and older old. PMID:26798962

  2. Helping Italian science teachers to make earth and climate active lessons. Results of 3 years support with the ICLEEN project

    NASA Astrophysics Data System (ADS)

    Cattadori, M.

    2013-12-01

    collaboration with the University of Trento dealing with the effectiveness of the service as well as the usability of the graphic user interface (GUI). The present work aims to illustrate the essential features of the service I-cleen and the results achieved during the last three years of operation. It will be display and interpret for the first time data with web traffic, and other data from downloading and publishing documents of the teaching resources and the main outcomes of the above mentioned tests. The purpose of this contribution is to highlight strengths and weaknesses of this experience and potentially able to provide valuable information on the role of today's web based services and online communities to help support teachers in earth and climate sciences subjects.

  3. Erosion and Deposition Patterns of the Mississippi River as a Result of the "100-Year" Flood Event of April 2011

    NASA Astrophysics Data System (ADS)

    Meyer, D.; Magnani, M.; McIntosh, K. D.

    2011-12-01

    Due to damming in the upper Mississippi River system, rates of sedimentation on the Mississippi River have decreased by more than half since the 1930s, which has resulted in the subsidence of the historic deltaic systems. In order to counteract this trend, the US Army Corps of Engineers (USACE) have diverted most of the Mississippi River sediment flow towards the current deltaic system, although there is concern that current sediment deposition rates may not be enough. Modern land loss along the Mississippi River deltaic plain is a function of many parameters, including the sediment storage and the sediment budget of the river. These parameters are poorly constrained for most rivers. This study explores the possibility of estimating the amount of sediment mobilization during the "100-Year" flood that took place in April 2011 in the portion of the Mississippi River flowing by Memphis, Tennessee. The opportunity to acquire high resolution seismic CHIRP data along the Mississippi River immediately after the flood allows us to compare the new data with similar data acquired in September 2009 in the same part of the river, to evaluate changes sedimentary structures and in the sediment removal/deposition due to the exceptional flooding event. The data were acquired in both cases using an Edgetech SB-512i CHIRP, a 0.7 - 1.2 kHz source pulse, and were recorded to a depth of 5 - 50 m sub-bottom. The compared segments were taken along the same 20 km track of river and comparisons were drawn between them at 9 intersection points. Two main observations can be made from the preliminary analysis of the two datasets: 1) the 2011 data show evidence of widespread erosion and limited deposition. Up to 6 m of alluvium appear to have been eroded from the river bottom. Where sediments have been newly deposited, they are characterized by massive appearance and lack of internal structure; 2) the wavelengths of the sandbars imaged in the post-flood data are 1.5 - 3 times longer than those

  4. Chemical and physical properties of comets in the Lowell database: Results from 35 years of narrow-band photometry

    NASA Astrophysics Data System (ADS)

    Schleicher, D.; Bair, A.

    2014-07-01

    As remnants from the epoch of early solar-system formation, comet nuclei are less processed than any other class of objects currently available for detailed study. Consequently, differences in the chemical composition among comets can indicate either differences in protoplanetary material and primordial conditions in our solar system or subsequent evolutionary effects. By gathering chemical and physical data on a large sample of comets and correlating these with dynamical properties, we can perform statistical analyses to determine the actual cause of a specific difference in properties. We have recently completed a new uniform reduction and set of analyses of the Lowell comet database, which includes 35 years of narrowband photometry of 167 comets. To minimize uncertainties due to too few data points or other systematics, a restricted subset of the database was created for chemical compositional studies, and mean abundance ratios were computed for each of these 101 comets. We used a variety of taxonomic techniques to identify seven compositional classes and to determine the membership of each class. Several classes are simply sub-groups of the original carbon-chain depleted class as defined by A'Hearn et al. (1995); all evidence continues to indicate that carbon-chain depletion reflects the primordial composition at the time and location of cometary accretion and is not associated with evolution. Among the other new classes is one containing five comets that are depleted in ammonia but are not depleted in carbon-chain molecules, but it is unclear if this compositional class is primordial or not. Other, non-compositional analyses were performed, using appropriate sub-sets of the entire database for each investigation. These included active areas, active fractions, and the behavior of the dust-to-gas ratio. Regarding the dust-to-gas ratio, we observed trends with respect to both perihelion distance and to age, implying an evolution of the surface of the nucleus

  5. Above-knee amputation followed by femoral replantation: 21-year follow-up results after lower limb replantation.

    PubMed

    Renner, Antal; Szentirmai, Annamária; Sántha, Andrea; Viola, Tamás; Gyárfás, Ferenc; Melly, András; Varga, Péter; Retteghy, Tibor

    2016-08-01

    In this article, we report successful treatment of serious complications of replantation after traumatic mid-third femoral amputation. To the best of our knowledge, no similar case has been reported in the literature. A 38-year-old healthy male sustained a mid-third right traumatic femoral amputation. We performed replantation. Oliguria and anuria occurred and were treated successfully with hemofiltration and hemodialysis. Six years later, patient walked wearing orthopedic shoes and also protective sensibility recovered on the limb. Serious complications of proximal lower limb replantation can be treated successfully and the limb can be saved. PMID:27499326

  6. Large Renal Artery Aneurysm Treated with Guglielmi Detachable Coils: Procedural and 4-Year Follow-up Results

    SciTech Connect

    Damascelli, Bruno; Bartorelli, Antonio L.; Ticha, Vladimira; Trabattoni, Daniela; Lanocita, Rodolfo

    2008-07-15

    A large aneurysm of the left renal artery was found incidentally during abdominal ultrasound in a 39-year-old woman with no medical or family history of cardiovascular disease. Vascular pathology with a dysplastic appearance was confirmed by magnetic resonance angiography and the patient was offered transcatheter embolization. Since the position and size of the neck of the aneurysm could not be determined at angiography, detachable platinum coils were used for occlusion. The procedure was performed without complications. During a 4-year follow-up no alterations of renal function, recanalization of the aneurysm, or perfusion defects in the rest of the left renal circulation were noted.

  7. Guide for Accredited Private School Education Planning and Results Reporting. Requirements for Three-Year Education Plans for 2007/08-2009/10 and Annual Education Results Reports for November 2007

    ERIC Educational Resources Information Center

    Online Submission, 2007

    2007-01-01

    The Guide to Accredited Private School Education Planning and Results Reporting, 2007-2010 provides the provincial requirements for: 1) Private school authority three-year education plans for 2007-2010. These plans cover the 2007/08, 2008/09 and 2009/10 school years. 2) Private school authority annual education results report for the 2006/07…

  8. 75 FR 81221 - Stainless Steel Sheet and Strip in Coils From Mexico; Preliminary Results of the Five-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ...-Year (``Sunset'') Review, 75 FR 30777 (June 2, 2010) (``Notice of Initiation''). The Department... of Antidumping Duty Orders, 75 FR 57899 (September 23, 2010). Scope of the Order For purposes of the... balance iron. Permanent magnet iron-chromium-cobalt alloy stainless strip is also excluded from the...

  9. Reading Performance of Elementary Students: Results of a Five-Year Longitudinal Study of Direct Reading Instruction

    ERIC Educational Resources Information Center

    Thames, Dana; Kazelskis, Richard; Kazelskis, Carolyn Reeves

    2006-01-01

    The purpose of this longitudinal study was to explore the impact of a direct reading instruction program, "Reading Mastery (RM)," on literacy performance of students over a five-year period. Initially, 700 students in grades K-3 were randomly selected from six elementary schools to participate in the study; an additional 100 randomly-selected…

  10. Risk Factors and Life Processes Associated with Teenage Pregnancy: Results of a Prospective Study from Birth to 20 Years.

    ERIC Educational Resources Information Center

    Woodward, Lianne; Fergusson, David M.; Horwood, L. John

    2001-01-01

    Data gathered during a 20-year longitudinal study of New Zealand women were used to describe the extent and timing of pregnancies within the cohort up to age 20; and to examine the extent to which the risk of early pregnancy was related to a range of social background, family, individual, and peer relationship factors measured over the course of…

  11. Impacts of Comprehensive Teacher Induction: Results from the Second Year of a Randomized Controlled Study. NCEE 2009-4072

    ERIC Educational Resources Information Center

    Isenberg, Eric; Glazerman, Steven; Bleeker, Martha; Johnson, Amy; Lugo-Gil, Julieta; Grider, Mary; Dolfin, Sarah; Britton, Edward

    2009-01-01

    One of the main policy responses to the problems of turnover and inadequate preparation among beginning teachers is to support them with a formal, comprehensive induction program. Congressional interest in formal, comprehensive teacher induction has grown in recent years. The No Child Left Behind Act of 2001 (NCLB), which reauthorized the…

  12. Impacts of Comprehensive Teacher Induction: Results from the First Year of a Randomized Controlled Study. NCEE 2009-4034

    ERIC Educational Resources Information Center

    Glazerman, Steven; Dolfin, Sarah; Bleeker, Martha; Johnson, Amy; Isenberg, Eric; Lugo-Gil, Julieta; Grider, Mary; Britton, Edward; Ali, Melanie

    2008-01-01

    In practice, teacher induction is common, but induction that is intensive, comprehensive, structured, and sequentially delivered in response to teachers' emerging pedagogical needs is less so. Congressional interest in formal, comprehensive teacher induction has grown in recent years. The National Center for Education Evaluation and Regional…

  13. Results from two years of ozone data taken with a new, ground-based microwave instrument: An overview

    NASA Technical Reports Server (NTRS)

    Parrish, A.; Connor, B. J.; Tsou, J. J.; Mcdermid, I. S.; Chu, W. P.; Siskind, D. E.

    1994-01-01

    An overview of two years of data obtained with a ground-based microwave instrument is given. Intercomparisons with data obtained by the co-located JPL lidar and by SAGE 2 during near overpasses of the site are discussed, as are comparisons with mesospheric data taken earlier by SME and LIMS. Observations of diurnal variations of mesospheric ozone are shown.

  14. Results of a 3-Year, Nutrition and Physical Activity Intervention for Children in Rural, Low-Socioeconomic Status Elementary Schools

    ERIC Educational Resources Information Center

    King, Kristi McClary; Ling, Jiying

    2015-01-01

    Improving children's nutrition and physical activity have become priorities in the United States. This quasi-experimental study evaluated the longitudinal effects of a 3-year, school-based, health promotion intervention (i.e. nutrition and physical education, classroom physical activity, professional development and health promotion for teachers…

  15. Fast Break to Learning School Breakfast Program: A Report of the Second Year Results, 2000-2001.

    ERIC Educational Resources Information Center

    Peterson, Kristin; Davison, Mark; Wahlstrom, Kyla; Himes, John; Irish, Margaret L.

    This report provides Year 2 data comparing two types of school breakfast programs in Minnesota to schools that did not serve breakfast at all (No Breakfast schools): Fast Break to Learning, a universal free breakfast program (Fastbreak schools), and programs with a sliding fee scale (control schools). Data were collected from 30 Fastbreak, 195…

  16. 75 FR 60084 - Purified Carboxymethylcellulose from Mexico: Preliminary Results of the First Five-year (“Sunset...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... Initiation of Five-year (``Sunset'') Review, 75 FR 30777 (June 2, 2010) (Notice of Initiation). The... Initiation from the domestic interested party and respondent interested party, Quimica Amtex S.A. de C.V. (Quimica Amtex), within the 30-day deadline specified in 19 CFR 351.218(d)(3)(i).\\1\\ The Department did...

  17. What Can Influence Students' Environmental Attitudes? Results from a Study of 15-Year-Old Students in France

    ERIC Educational Resources Information Center

    Le Hebel, Florence; Montpied, Pascale; Fontanieu, Valérie

    2014-01-01

    The purpose of this study is to investigate the environmental attitudes (EA) in the population of 15-year-old French students and, to check if the French student population presents similar EA categorization as described in the different models in the literature (e.g. the Model of Ecological Values, Wiseman & Bogner 2003). The second aim of…

  18. Finnish Parental Involvement Ethos, Health Support, Health Education Knowledge and Participation: Results from a 2-Year School Health Intervention

    ERIC Educational Resources Information Center

    Sormunen, Marjorita; Tossavainen, Kerttu; Turunen, Hannele

    2013-01-01

    A 2-year, participatory action research school health study focused on developing components for home-school partnerships to support children's health learning process. Two intervention schools implemented strengthened health and collaboration-orientated activities; two control schools followed the national core curriculum without extracurricular…

  19. An Investigation on Industry-Sponsored Design Projects' Effectiveness at the First-Year Level: Potential Issues and Preliminary Results

    ERIC Educational Resources Information Center

    Okudan, Gul E.; Mohammed, Susan; Ogot, Madara

    2006-01-01

    This paper presents the preliminary work for developing guidelines to ensure that industry-sponsored projects in first-year courses aid, not hamper, retention of students. Specifically, the overall research plan includes the following steps: (1) investigating the appropriateness of industry projects in a required introduction to engineering design…

  20. Three-Year Results of the Friendly Schools Whole-of-School Intervention on Children's Bullying Behaviour

    ERIC Educational Resources Informati