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Sample records for 10-24 years result

  1. Homicide rates among persons aged 10-24 years - United States, 1981-2010.

    PubMed

    2013-07-12

    Homicide disproportionately affects persons aged 10-24 years in the United States and consistently ranks in the top three leading causes of death in this age group, resulting in approximately 4,800 deaths and an estimated $9 billion in lost productivity and medical costs in 2010. To investigate trends in homicide among persons aged 10-24 years for the period 1981-2010, CDC analyzed National Vital Statistics System data on deaths caused by homicide of persons in this age group and examined trends by sex, age, race/ethnicity, and mechanism of injury. This report describes the results of that analysis, which indicated that homicide rates varied substantially during the study period, with a sharp rise from 1985 to 1993 followed by a decline that has slowed since 1999. During the period 2000-2010, rates declined for all groups, although the decline was significantly slower for males compared with females and for blacks compared with Hispanics and persons of other racial/ethnic groups. By mechanism of injury, the decline for firearm homicides from 2000 to 2010 was significantly slower than for nonfirearm homicides. The homicide rate among persons aged 10-24 years in 2010 was 7.5 per 100,000, the lowest in the 30-year study period. Primary prevention strategies remain critical, particularly among groups at increased risk for homicide.

  2. Suicide in young Singaporeans aged 10-24 years between 2000 to 2004.

    PubMed

    Loh, Cheryl; Tai, Bee-Choo; Ng, Wai-Yee; Chia, Audrey; Chia, Boon-Hock

    2012-01-01

    The objective of this study was to understand the features of young suicide in order to contribute to suicide prevention efforts. In this article, the demographic, clinical, and suicide-related features of all cases of young suicide (aged 10-24 years) in Singapore for the years 2000-2004 are described. We also compared those who sought mental health services to those who did not. Overall, the suicide rate was 5.7 per 100, 000, with gender ratio of 1:1 and higher rates among ethnic Indians. Psychosocial stressors and suicide by jumping from height were common. Mental health service use was associated with unemployment, previous suicide attempts, family history of suicide, more use of lethal methods, lack of identifiable stressor, and less suicide notes. Suicide prevention efforts should promote awareness of suicide risks and access to mental health services.

  3. 19 CFR 10.24 - Documentation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... with United States Components § 10.24 Documentation. (a) Documents required. The following documents... abroad shall be filed in substantially the following form: I, _____, declare that to the best of my knowledge and belief the _____ were assembled in whole or in part from fabricated components listed...

  4. First year results from LOTIS

    NASA Astrophysics Data System (ADS)

    Williams, G. G.; Parks, H. S.; Ables, E.

    1997-11-01

    LOTIS (Livermore Optical Transient Imaging System) is a gamma-ray burst optical couterpart search experiment located near Lawrence Livermore National Laboratory in California. The system is linked to the GCN (GRB Coordinates Network) real-time coordinate distribution network and can respond to a burst trigger in 6-15 seconds. LOTIS has a total field-of-view of 17.4 degrees x 17.4 degrees with a completeness sensitivity of mv approximately 11 for a 10 second integration time. Since operations began in October 1996, LOTIS has responded to over 30 GCN/BATSE GRB triggers. Seven of these triggers are considered good events subject to the criteria of clear weather conditions, (lt) 60 S RESPONSE TIME, AND (gt)50% coverage of the final BATSE 3(sigma) error circle. We discuss results from the first year of LOTIS operations with an emphasis on the observations and analysis of GRB 971006 (BATSE trigger 6414) .

  5. 27 CFR 10.24 - Sales promotion contests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Sales promotion contests. 10.24 Section 10.24 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS COMMERCIAL BRIBERY Commercial Bribery § 10.24 Sales promotion...

  6. 10 CFR 10.24 - Procedures for hearing and review.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Procedures for hearing and review. 10.24 Section 10.24... RESTRICTED DATA OR NATIONAL SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.24 Procedures for... requirements set forth in § 10.22, the Director, Office of Administration, shall forthwith appoint a...

  7. 10 CFR 10.24 - Procedures for hearing and review.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Procedures for hearing and review. 10.24 Section 10.24... RESTRICTED DATA OR NATIONAL SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.24 Procedures for... requirements set forth in § 10.22, the Director, Office of Administration, shall forthwith appoint a...

  8. 10 CFR 10.24 - Procedures for hearing and review.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Procedures for hearing and review. 10.24 Section 10.24... RESTRICTED DATA OR NATIONAL SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.24 Procedures for... requirements set forth in § 10.22, the Director, Office of Administration, shall forthwith appoint a...

  9. 10 CFR 10.24 - Procedures for hearing and review.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Procedures for hearing and review. 10.24 Section 10.24... RESTRICTED DATA OR NATIONAL SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.24 Procedures for... requirements set forth in § 10.22, the Director, Office of Administration, shall forthwith appoint a...

  10. 10 CFR 10.24 - Procedures for hearing and review.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Procedures for hearing and review. 10.24 Section 10.24... RESTRICTED DATA OR NATIONAL SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.24 Procedures for... requirements set forth in § 10.22, the Director, Office of Administration, shall forthwith appoint a...

  11. 17 CFR 10.24 - Amendments and supplemental pleadings.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... pleadings. 10.24 Section 10.24 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION RULES OF PRACTICE Institution of Adjudica- tory Proceedings; Pleadings; Motions § 10.24 Amendments and... amend a complaint to correct typographical and clerical errors or to make other technical,...

  12. 37 CFR 10.24 - Disclosure of information to authorities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... authorities. 10.24 Section 10.24 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE... practitioner possessing unprivileged knowledge of a violation of a Disciplinary Rule shall report such knowledge to the Director. (b) A practitioner possessing unprivileged knowledge or evidence...

  13. Nebraska wind resource assessment first year results

    SciTech Connect

    Hurley, P.J.F.; Vilhauer, R.; Stooksbury, D.

    1996-12-31

    This paper presents the preliminary results from a wind resource assessment program in Nebraska sponsored by the Nebraska Power Association. During the first year the measured annual wind speed at 40 meters ranged from 6.5 - 7.5 m/s (14.6 - 16.8 mph) at eight stations across the state. The site selection process is discussed as well as an overview of the site characteristics at the monitoring locations. Results from the first year monitoring period including data recovery rate, directionality, average wind speeds, wind shear, and turbulence intensity are presented. Results from the eight sites are qualitatively compared with other midwest and west coast locations. 5 figs., 2 tabs.

  14. FIVE-YEAR RESULTS OF ADJUVANT RADIOTHER

    PubMed Central

    Osa, Etin-Osa O.; DeWyngaert, Keith; Roses, Daniel; Speyer, James; Guth, Amber; Axelrod, Deborah; Kerimian, Maria Fenton; Goldberg, Judith D.; Formenti, Silvia C.

    2015-01-01

    Purpose/Objective A technique of prone breast radiotherapy delivered by a regimen of accelerated intensity modulated radiation therapy (IMRT) with a concurrent boost to the tumor bed, was developed at our institution. We report the five year results of this approach. Methods and Materials Between 2003–2006, 404 patients with Stage I–II breast cancer were prospectively enrolled into two consecutive protocols, institutional trials 03–30 and 05–181, that used the same regimen of 40.5Gy/15 fractions delivered to the index breast over 3 weeks, with a concomitant daily boost to the tumor bed of 0.5Gy (total dose=48Gy). All patients were treated after segmental mastectomy, had negative margins, and nodal assessment. Patients were set up prone: only if lung or heart volumes were in the field was a supine set-up attempted, and chosen if found to better spare these organs. Results 92% of patients were treated prone, 8% supine. 72% had stage I, 28% stage II invasive breast cancer. In-field lung volume ranged from 0 –228.27cc, mean: 19.65cc. In-field heart volume for left breast cancer patients ranged from 0–21.24cc, mean: 1.59cc. There was no heart in the field for right breast cancer patients. At a median follow-up of five years, the five-year cumulative incidence of isolated ipsilateral breast tumor recurrence was 0.82% (95% CI: 0.65–1.04). The five-year cumulative incidence of regional recurrence was 0.53% (95% CI:0.41–0.69) and the five-year overall cumulative death rate was 1.28% (95% CI: 0.48–3.38). 82% (95% CI: 77–85) of patients judged their final cosmetic result as excellent/good. Conclusions Prone accelerated IMRT with a concomitant boost results in excellent local control, optimal sparing of heart and lung, with good cosmesis. RTOG 10–05, a phase III, multi-institutional, randomized trial is ongoing and is evaluating the equivalence of a similar dose and fractionation approach to standard six weeks radiotherapy with a sequential boost. PMID

  15. Modelfest: year one results and plans for future years

    NASA Astrophysics Data System (ADS)

    Carney, Thom; Tyler, Christopher W.; Watson, Andrew B.; Makous, Walter; Beutter, Brent; Chen, Chien-Chung; Norcia, Anthony M.; Klein, Stanley A.

    2000-06-01

    A robust model of the human visual system (HVS) would have a major practical impact on the difficult technological problems of transmitting and storing digital images. Although most HVS models exhibit similarities, they may have significant differences in predicting performance. Different HVS models are rarely compared using the same set of psychophysical measurements, so their relative efficacy is unclear. The Modelfest organization was formed to solve this problem and accelerate the development of robust new models of human vision. Members of Modelfest have gathered psychophysical threshold data on the year one stimuli described at last year's SPIE meeting. Modelfest is an exciting new approach to modeling involving the sharing of resources, learning from each other's modeling successes and providing a method to cross-validate proposed HVS models. The purpose of this presentation is to invite the Electronic Imaging community to participate in this effort and inform them of the developing database, which is available to all researchers interested in modeling human vision. In future years, the database will be extended to other domains such as visual masking, and temporal processing. This Modelfest progress report summarizes the stimulus definitions and data collection methods used, but focuses on the results of the phase one data collection effort. Each of the authors has provided at least one dataset from their respective laboratories. These data and data collected subsequent to the submission of this paper are posted on the WWW for further analysis and future modeling efforts.

  16. First year results from the HAWC observatory

    NASA Astrophysics Data System (ADS)

    Casanova, Sabrina

    2017-03-01

    The High Altitude Water Cherenkov Observatory is an all-sky surveying instrument sensitive to gamma rays and cosmic rays from 100GeV to 100TeV. With its 2sr instantaneous field of view and a duty cycle of > 95%, HAWC is carrying out an unbiased survey of the Northern sky and is monitoring known flaring sources and searching for transients. HAWC operation began mid-2013 with a partially-completed detector. The array was terminated in 2015. We here summarize the status of the observatory, and highlight its first scientific results, resulting from the first year of data taking after completion of the detector. In particular, we will present the HAWC map of the sky at tens of TeV.

  17. Results from Four Years of Venus Express

    NASA Astrophysics Data System (ADS)

    Svedhem, Hakan; Titov, D.; Taylor, F.

    2010-10-01

    Since arriving at Venus in April 2006 Venus Express has provided a wealth of information on a large variety of topics on the atmosphere, surface and plasma environment of the planet. The atmosphere in the southern hemisphere has been studied in detail by three instruments dedicated to atmospheric investigations, from the near IR to the UV and additional information has been derived from radio science measurements. The structure and composition of the atmosphere has been mapped in three dimensions from 40 km to 140 km altitude. Significant temporal and spatial variations have been found, both in composition, density and temperature. Imaging in the UV has revealed strong latitudinal variations and significant temporal changes in the global cloud top morphology as well as identification of various types of waves in the cloud layer. The cloud top altitude varies from about 72 km in the low and middle latitudes to about 64 km in the polar region, marking vast polar depressions, likely a result of the Hadley-type meridional circulation. A large amount of data on the atmospheric circulation has been collected and results include maps of wind speeds at different altitudes and movies of the dynamics of the southern polar vortex. A surface temperature map and an emissivity map of the full southern hemisphere have been constructed from IR images in the spectral windows. By correlating these results and the Magellan radar images and gravity data, regions of young unweathered surfaces likely due to recent volcanism have been identified. The induced magnetosphere with its boundaries and the escape of planetary matter have been characterized by a magnetometer and an energetic particle instrument, and escape rates of hydrogen, oxygen and helium have been determined.A decision to extend the mission until end 2014 is expected at the end of this year.

  18. Fermi GBM: Results from the First Year +

    NASA Technical Reports Server (NTRS)

    Wilson-Hodge, Colleen A.

    2009-01-01

    Gamma-ray Burst Monitor (GBM) has performed well in the first year+. GBM triggers 353 Gamma-ray Bursts (GRBs), 168 SGR events, 18 TGFs, and 1 solar flare to date. Short GRBs appear contracted in time and shifted to higher energy than long GRBs. Pulsed persistent emission from SGR 1550-5418 detected. TGFs are shorter, have higher average photon energies, and much higher count rates than GRBs. GBM monitoring of accreting pulsars provides long-term spin-histories. GBM Earth occultation monitoring complements Swift.

  19. 46 CFR 31.10-24 - Integral fuel oil tank examinations-T/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Integral fuel oil tank examinations-T/ALL. 31.10-24 Section 31.10-24 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS INSPECTION AND CERTIFICATION Inspections § 31.10-24 Integral fuel oil tank examinations—T/ALL. (a) Each fuel oil tank with...

  20. [Results of 2 years of activity].

    PubMed

    Panigazzi, M

    2010-01-01

    Work-related injuries and occupational diseases are a scourge of modern, western societies, which, although technologically advanced, have difficulty in preventing, treating and rehabilitating victims with speed and efficiency. The current hospital neuromotor rehabilitation centres, whether public or accredited private structures, have notable difficulty in meeting the demand, which despite annual fluctuations and variable needs, does not, overall, seem to be decreasing. We present the results of an organization model developed at the "Fondazione Maugeri" Scientific Institute (Pavia, Italy), the criteria used for the activity, the technological innovations employed to determine ability, and the prospects for further development. This model is effective from a health care-rehabilitative point of view, also in the light of the new legislative scenarios, and is sustainable from an economic points of view; overall it is, therefore, efficient.

  1. 46 CFR 31.10-24 - Integral fuel oil tank examinations-T/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Integral fuel oil tank examinations-T/ALL. 31.10-24... CERTIFICATION Inspections § 31.10-24 Integral fuel oil tank examinations—T/ALL. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within the hull (integral fuel oil tank)...

  2. 46 CFR 31.10-24 - Integral fuel oil tank examinations-T/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Integral fuel oil tank examinations-T/ALL. 31.10-24... CERTIFICATION Inspections § 31.10-24 Integral fuel oil tank examinations—T/ALL. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within the hull (integral fuel oil tank)...

  3. 46 CFR 31.10-24 - Integral fuel oil tank examinations-T/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Integral fuel oil tank examinations-T/ALL. 31.10-24... CERTIFICATION Inspections § 31.10-24 Integral fuel oil tank examinations—T/ALL. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within the hull (integral fuel oil tank)...

  4. 46 CFR 31.10-24 - Integral fuel oil tank examinations-T/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Integral fuel oil tank examinations-T/ALL. 31.10-24... CERTIFICATION Inspections § 31.10-24 Integral fuel oil tank examinations—T/ALL. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within the hull (integral fuel oil tank)...

  5. Personal Access Satellite System (PASS) study. Fiscal year 1989 results

    NASA Technical Reports Server (NTRS)

    Sue, Miles K. (Editor)

    1990-01-01

    The Jet Propulsion Laboratory is exploring the potential and feasibility of a personal access satellite system (PASS) that will offer the user greater freedom and mobility than existing or currently planned communications systems. Studies performed in prior years resulted in a strawman design and the identification of technologies that are critical to the successful implementation of PASS. The study efforts in FY-89 were directed towards alternative design options with the objective of either improving the system performance or alleviating the constraints on the user terminal. The various design options and system issues studied this year and the results of the study are presented.

  6. Aquifer Sampling Tube Results for Fiscal Year 2003

    SciTech Connect

    Hartman, Mary J.; Peterson, Robert E.

    2003-10-27

    This report presents and discusses results of the fiscal year 2003 sampling event associated with aquifer tubes along the Columbia River in the northern Hanford Site. Aquifer tube data help define the extent of groundwater contamination near the river, determine vertical variations in contamination, monitor the performance of interim remedial actions near the river, and support impact studies.

  7. The Safe Dates program: 1-year follow-up results.

    PubMed Central

    Foshee, V A; Bauman, K E; Greene, W F; Koch, G G; Linder, G F; MacDougall, J E

    2000-01-01

    OBJECTIVES: An earlier report described desirable 1-month follow-up effects of the Safe Dates program on psychological, physical, and sexual dating violence. Mediators of the program-behavior relationship also were identified. The present report describes the 1-year follow-up effects of the Safe Dates program. METHODS: Fourteen schools were in the randomized experiment. Data were gathered by questionnaires in schools before program activities and 1 year after the program ended. RESULTS: The short-term behavioral effects had disappeared at 1 year, but effects on mediating variables such as dating violence norms, conflict management skills, and awareness of community services for dating violence were maintained. CONCLUSIONS: The findings are considered in the context of why program effects might have decayed and the possible role of boosters for effect maintenance. PMID:11029999

  8. Long Term Corrosion/Degradation Test Six Year Results

    SciTech Connect

    M. K. Adler Flitton; C. W. Bishop; M. E. Delwiche; T. S. Yoder

    2004-09-01

    The Subsurface Disposal Area (SDA) of the Radioactive Waste Management Complex (RWMC) located at the Idaho National Engineering and Environmental Laboratory (INEEL) contains neutron-activated metals from non-fuel, nuclear reactor core components. The Long-Term Corrosion/Degradation (LTCD) Test is designed to obtain site-specific corrosion rates to support efforts to more accurately estimate the transfer of activated elements to the environment. The test is using two proven, industry-standard methods—direct corrosion testing using metal coupons, and monitored corrosion testing using electrical/resistance probes—to determine corrosion rates for various metal alloys generally representing the metals of interest buried at the SDA, including Type 304L stainless steel, Type 316L stainless steel, Inconel 718, Beryllium S200F, Aluminum 6061, Zircaloy-4, low-carbon steel, and Ferralium 255. In the direct testing, metal coupons are retrieved for corrosion evaluation after having been buried in SDA backfill soil and exposed to natural SDA environmental conditions for times ranging from one year to as many as 32 years, depending on research needs and funding availability. In the monitored testing, electrical/resistance probes buried in SDA backfill soil will provide corrosion data for the duration of the test or until the probes fail. This report provides an update describing the current status of the test and documents results to date. Data from the one-year and three-year results are also included, for comparison and evaluation of trends. In the six-year results, most metals being tested showed extremely low measurable rates of general corrosion. For Type 304L stainless steel, Type 316L stainless steel, Inconel 718, and Ferralium 255, corrosion rates fell in the range of “no reportable” to 0.0002 mils per year (MPY). Corrosion rates for Zircaloy-4 ranged from no measurable corrosion to 0.0001 MPY. These rates are two orders of magnitude lower than those specified in

  9. THE TAOS PROJECT: RESULTS FROM SEVEN YEARS OF SURVEY DATA

    SciTech Connect

    Zhang, Z.-W.; Lehner, M. J.; Wang, J.-H.; Wen, C.-Y.; Wang, S.-Y.; King, S.-K.; Cook, K. H.; Lee, T.; Granados, A. P.; Alcock, C.; Protopapas, P.; Axelrod, T.; Bianco, F. B.; Byun, Y.-I.; Chen, W. P.; Coehlo, N. K.; De Pater, I.; Kim, D.-W.; Lissauer, J. J.; Marshall, S. L.; and others

    2013-07-01

    The Taiwanese-American Occultation Survey (TAOS) aims to detect serendipitous occultations of stars by small ({approx}1 km diameter) objects in the Kuiper Belt and beyond. Such events are very rare (<10{sup -3} events per star per year) and short in duration ({approx}200 ms), so many stars must be monitored at a high readout cadence. TAOS monitors typically {approx}500 stars simultaneously at a 5 Hz readout cadence with four telescopes located at Lulin Observatory in central Taiwan. In this paper, we report the results of the search for small Kuiper Belt objects (KBOs) in seven years of data. No occultation events were found, resulting in a 95% c.l. upper limit on the slope of the faint end of the KBO size distribution of q = 3.34-3.82, depending on the surface density at the break in the size distribution at a diameter of about 90 km.

  10. Prone Breast Intensity Modulated Radiation Therapy: 5-Year Results

    SciTech Connect

    Osa, Etin-Osa O.; DeWyngaert, Keith; Roses, Daniel; Speyer, James; Guth, Amber; Axelrod, Deborah; Fenton Kerimian, Maria; Goldberg, Judith D.; Formenti, Silvia C.

    2014-07-15

    Purpose: To report the 5-year results of a technique of prone breast radiation therapy delivered by a regimen of accelerated intensity modulated radiation therapy with a concurrent boost to the tumor bed. Methods and Materials: Between 2003 and 2006, 404 patients with stage I-II breast cancer were prospectively enrolled into 2 consecutive protocols, institutional trials 03-30 and 05-181, that used the same regimen of 40.5 Gy/15 fractions delivered to the index breast over 3 weeks, with a concomitant daily boost to the tumor bed of 0.5 Gy (total dose 48 Gy). All patients were treated after segmental mastectomy and had negative margins and nodal assessment. Patients were set up prone: only if lung or heart volumes were in the field was a supine setup attempted and chosen if found to better spare these organs. Results: Ninety-two percent of patients were treated prone, 8% supine. Seventy-two percent had stage I, 28% stage II invasive breast cancer. In-field lung volume ranged from 0 to 228.27 cm{sup 3}, mean 19.65 cm{sup 3}. In-field heart volume for left breast cancer patients ranged from 0 to 21.24 cm{sup 3}, mean 1.59 cm{sup 3}. There was no heart in the field for right breast cancer patients. At a median follow-up of 5 years, the 5-year cumulative incidence of isolated ipsilateral breast tumor recurrence was 0.82% (95% confidence interval [CI] 0.65%-1.04%). The 5-year cumulative incidence of regional recurrence was 0.53% (95% CI 0.41%-0.69%), and the 5-year overall cumulative death rate was 1.28% (95% CI 0.48%-3.38%). Eighty-two percent (95% CI 77%-85%) of patients judged their final cosmetic result as excellent/good. Conclusions: Prone accelerated intensity modulated radiation therapy with a concomitant boost results in excellent local control and optimal sparing of heart and lung, with good cosmesis. Radiation Therapy Oncology Group protocol 1005, a phase 3, multi-institutional, randomized trial is ongoing and is evaluating the equivalence of a similar dose and

  11. Results of a two-year in situ bioventing demonstration

    SciTech Connect

    Downey, D.C.; Guest, P.R.; Ratz, J.W.

    1995-05-01

    A full-scale bioventing demonstration was recently completed at a large diesel spill site located at a major railroad facility in Nebraska. An estimated 11,500 cubic meters of soil are being treated in this demonstration. During this two-year demonstration, both in situ respiration rates and volatilization were routinely monitored to estimate total fuel removal rates. This paper discusses the relative contributions of biodegradation and volatilization in this bioventing application and presents two-year soil sampling results which indicate that significant fuel remediation has occurred at the site. Both capital and operating costs for this system are very competitive and will be detailed in this document. 10 refs., 5 figs.

  12. Immunologic effects of emdogain in humans: one-year results.

    PubMed

    Nikolopoulos, Symeon; Peteinaki, Efthymia; Castanas, Elias

    2002-06-01

    Tissue regeneration after therapeutic manipulations is essential in periodontology, oral surgery, and trauma of the periodontal tissues. Local inflammation because of poor oral hygiene also plays a crucial role in the above situations. Local inflammatory reaction, accompanied by the local production of cytokines, profoundly influences bone turnover and regeneration. Several products of low immunogenicity for augmenting tissue regeneration have been recently proposed as boosters of soft and mineralized tissue regeneration. Among them, Emdogain, an amelogenin derivative of porcine origin, has recently been introduced. Clinical results indicate that this product might be a good additive, producing fast tissue regeneration with no apparent clinical side effects. In contrast, very little is known about its in vivo immunologic effects. A previous study showed that Emdogain does not modify the cellular or humoral immune response in vitro. In the present work, performed in 10 patients, only a slight, nonsignificant activation of the immune system occurred during the first year following Emdogain application. Neither cellular immunity nor humoral immune response was significantly modified. In addition, the in vitro response of the patients' lymphocytes to Emdogain was assayed 2 and 12 months postoperative. We did not find any significant specific lymphocyte transformation in the presence of Emdogain, although lymphocytes could be stimulated by nonselective mitogens. These results indicate the immunologic safety of the agent in vivo, at least after 1 year.

  13. Bilateral trans-humeral arm transplantation: result at 2 years.

    PubMed

    Cavadas, P C; Ibáñez, J; Thione, A; Alfaro, L

    2011-05-01

    Unilateral and bilateral hand transplantations have been performed worldwide with good mid-term functional results. An above-elbow bilateral transplantation was performed in a 29-year-old male patient from a fully HLA-mismatched donor. Alemtuzumab induction and steroid-free maintenance immunosuppression with tacrolimus and mycophenolate was used. Due to acute rejection, steroids were introduced at 6 months. Three acute rejection episodes occurred, one treated with alemtuzumab. New-onset diabetes after transplant, dyslipemia and worsening of previous high blood pressure required treatment. At 26 months post-transplantation, the patient has excellent elbow active movement, active flexion and extension of the thumb and fingers, useful sensation and a gainful job. Based on the functional results of the case reported, bilateral trans-humeral transplantation could be a viable treatment for selected bilateral above-elbow amputees.

  14. COBE-DMR two-year large scale anisotropy results

    NASA Astrophysics Data System (ADS)

    Bennett, C. L.; Banday, A.; Górski, K.; Hinshaw, G.; Kogut, A.; Wright, E. L.

    1995-07-01

    We summarize the results of the Cosmic Microwave Background (CMB) anisotropy measurements of the COBE-DMR using the first two years of data. The inference of angular power spectrum parameters from the DMR data is complicated by the need to omit Galaxy contaminated regions of the sky, preventing the spherical harmonics from forming an orthogonal basis set over the remaining sky. The COBE-DMR team has implemented three methods for deducing the power spectrum parameters. These include: a two-point correlation function analysis (Bennett et al. 1994); an analysis in terms of orthogonal modes constructed on the cut sphere (Górski et al. 1994); and an analysis of a modified Hauser-Peebles power spectrum (Wright et al. 1994). These methods for deducing the power spectrum are discussed and the results are summarized and compared.

  15. DOE radiological calibrations intercomparison program: Results of fiscal year 1986

    SciTech Connect

    Cummings, F.M.; Roberson, P.L.; McDonald, J.C.

    1987-05-01

    The Department of Energy Radiological Calibration Intercomparison Program was initiated in January 1986, under the research portion of the DOE Laboratory Accreditation Program. The program operates via the exchange of transfer standards, consisting of instrument sets and standard secondary beta sources. There are two instrument sets and the scheduled use has been staggered such that one set is available for use during each month. One set of secondary standard beta sources is available for use bimonthly. During the 1986 fiscal year, five laboratories used the instrument sets and three laboratories used the beta source set. Results were reported for all the measurements. The average and one standard deviation of the ratios of participant results to Pacific Northwest Laboratory calibration values were 1.12 +- 0.17 for gamma measurements. Those ratios for the gamma measurements varied from 0.98 to 3.06. The larger differences of results from measurements performed at two facilities were directly attributable to unfamiliarity with the intercomparison instruments. The average and one standard deviation of the ratios of participant results to PNL calibration values obtained using the secondary /sup 90/Sr beta source was 1.02 +- 0.05, which is well within measurement uncertainties. The one participant who performed measurements using /sup 147/Pm and /sup 204/Tl sources obtained ratios of 0.68 and 1.11, respectively. No measurements were performed using neutron or x-ray sources.

  16. Michigan Oncology Medical Home Demonstration Project: first-year results.

    PubMed

    Kuntz, Gordon; Tozer, Jane M; Snegosky, Jeff; Fox, John; Neumann, Kurt

    2014-09-01

    Launched in May 2012, the Michigan Oncology Medical Home Demonstration Project is an innovative multipractice oncology medical home model supported by payment reform. In the first year of the project, four oncology practices (29 physicians) participated and enrolled 85 patients receiving chemotherapy for a cancer diagnosis (96 new chemotherapy starts). By creating an oncology medical home for patients, the project reduced costs associated with unnecessary emergency room visits and inpatient admissions, with an average estimated cost savings of $550 per patient, while also enhancing payments to providers. The total estimated cost savings for year 1 was $46,228. In addition to the financial savings realized through reductions in emergency room visits and hospitalizations, the program also demonstrated that participating practices had high adherence to national and practice-selected guidelines, instituted advance care planning, and provided effective and standardized symptom management. The results are promising and provide evidence that community oncology practices will embrace the transformation to a patient-centered model with properly aligned incentives and administrative assistance.

  17. Field Lysimeter Test Facility: Second year (FY 1989) test results

    SciTech Connect

    Campbell, M.D.; Gee, G.W.; Kanyid, M.J.; Rockhold, M.L.

    1990-04-01

    The Record of Decision associated with the Hanford Defense Waste Environmental Impact Statement (53 FR 12449-53) commits to an evaluation of the use of protective barriers placed over near-surface wastes. The barrier must protect against wind and water erosion and limit plant and animal intrusion and infiltration of water. Successful conclusion of this program will yield the necessary protective barrier design for near-surface waste isolation. This report presents results from the second year of tests at the FLTF. The primary objective of testing protective barriers at the FLTF was to measure the water budgets within the various barriers and assess the effectiveness of their designs in limiting water intrusion into the zone beneath each barrier. Information obtained from these measurements is intended for use in refining barrier designs. Four elements of water budget were measured during the year: precipitation, evaporation, storage, and drainage. Run-off, which is a fifth element of a complete water budget, was made negligible by a lip on the lysimeters that protrudes 5 cm above the soil surface to prevent run-off. A secondary objective of testing protective barriers at the FLTF was to refine procedures and equipment to support data collection for verification of the computer model needed for long-term projections of barrier performance. 6 refs.

  18. First year results of the High Altitude Water Cherenkov observatory

    NASA Astrophysics Data System (ADS)

    Carramiñana, Alberto

    2016-10-01

    The High Altitude Water Cherenkov (HAWC) γ-ray observatory is a wide field of view (1.8 Sr) and high duty cycle (> 95% up-time) detector of unique capabilities for the study of TeV gamma-ray sources. Installed at an altitude of 4100m in the Northern slope of Volcan Sierra Negra, Puebla, by a collaboration of about thirty institutions of Mexico and the United States, HAWC has been in full operations since March 2015, surveying 2/3 of the sky every sidereal day, monitoring active galaxies and mapping sources in the Galactic Plane to a detection level of 1 Crab per day. This contribution summarizes the main results of the first year of observations of the HAWC γ-ray observatory.

  19. Preliminary medical results of the Mir year-long mission

    NASA Astrophysics Data System (ADS)

    Grigoriev, A. I.; Bugrov, S. A.; Bogomolov, V. V.; Egorov, A. D.; Kozlovskaya, I. B.; Pestov, I. D.; Polyakov, V. V.; Tarasov, I. K.

    The basic goal of medical investigations during and after the 366-day mission was to accumulate data about physiological responses to such a long exposure to microgravity. In flight, cardiovascular and other systems were examined in detail and the efficacy of countermeasures used was assessed. After flight, physiological systems were also followed very carefully. According to the preliminary data, the medical results obtained during and after flight give evidence that man can well adapt to a year-long space flight, maintaining good health and adequate work capacity. The readaptation process was very similar to that observed after shorter flights (6-II months). As compared to former flights, no new or qualitatively different changes in the vital systems of the body were seen. The observations indicate that the duration of manned space missions can be further increased.

  20. Four years of operations and results with FORTE

    SciTech Connect

    Klingner, P. L.; Carlson, L. D.; Dingler, R. D.; Esch-Mosher, D. M.; Jacobson, A. R.; Roussel-Dupre, D.

    2001-01-01

    The FORTE (Fast Onboard Recording of Transient Events) satellite was launched on 29 August 1997 and has been in continuous operation since that time. FORTE was placed in a nearly circular, 825-km-altitude, 70 degrees inclination orbit by a Pegasus rocket funded by Air Force Space Test Program. The Department of Energy funded the FORTE satellite, which was designed and built at Los Alamos. FORTE's successful launch and engineered robustness were a result of several years of dedicated work by the joint Los Alamos National Laboratory/Sandia National Laboratory project team, led through mission definition, payload and satellite development, and launch by Dr. Stephen Knox. The project is now led by Dr. Abram Jacobson. FORTE carries a suite of instruments, an optical system and a rf system, for the study of lightning and anthropogenic signals. As a result of this effort, new understandings of lightning events have emerged as well as a more complete understanding of the relationship between optical and rf lightning events. This paper will provide an overview of the FORTE satellite and will discuss the on orbit performance of the subsystems.

  1. FOUR YEARS OF OPERATIONS AND RESULTS WITH FORTE

    SciTech Connect

    D. ROUSSEL-DUPRE; P. KLINGNER; L. CARLSON; ET AL

    2001-06-01

    The FORTE (Fast Onboard Recording of Transient Events) satellite was launched on 29 August 1997 and has been in continuous operation since that time. FORTE was placed in a nearly circular, 825-km-altitude, 70 degrees inclination orbit by a Pegasus rocket funded by Air Force Space Test Program. The Department of Energy funded the FORTE satellite, which was designed and built at Los Alamos. FORTE's successful launch and engineered robustness were a result of several years of dedicated work by the joint Los Alamos National Laboratory/Sandia National Laboratory project team, led through mission definition, payload and satellite development, and launch by Dr. Stephen Knox. The project is now led by Dr. Abram Jacobson. FORTE carries a suite of instruments, an optical system and a rf system, for the study of lightning and anthropogenic signals. As a result of this effort, new understandings of lightning events have emerged as well as a more complete understanding of the relationship between optical and rf lightning events. This paper will provide an overview of the FORTE satellite and will discuss the on orbit performance of the subsystems.

  2. Illinois Community College System Results Report, Fiscal Year 2002.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    This report details the ways in which the Illinois Community College System is addressing its strategic plan, "Promise for Illinois," for fiscal year 2002. Illinois has 39 community college districts and one multi-community college center that serve nearly one million students a year. The report identifies the following six goals: (1)…

  3. Astronomers celebrate a year of new Hubble results

    NASA Astrophysics Data System (ADS)

    1995-02-01

    Space Telescope to make accurate measurements of the distance of Ml 00, a far away galaxy located in the Virgo cluster of galaxies. To do this they used a number of Cepheid variable stars, rare objects that change in brightness over a regular period. Because astronomers know that there is a direct link between the period of the Cepheid's pulsation and its actual brightness, they can do a simple calculation to work out the distance to the object by comparing its actual brightness with how bright it appears to Hubble. The astronomers had to study more than 40,000 stars before finding the 20 Cepheids they used for their calculations. The results revealed that M100 lies 56 million light years from Earth. With this, astronomers calculated that the Universe is expanding at a rate of 80 kilometres per second per megaparsec (a megaparsec is 3,261,600 light years). This is much faster than astronomers had expected. On the basis of this value for the Hubble Constant, the Universe must be aged somewhere between eight and twelve billion years old. But, this flies in the face of established facts. We know there are stars in our Universe that are 16 billion years old - how can they be older than the Universe in which they exist? It could be that the theory that explains the evolution of stars or the Big Bang theory are wrong. Or perhaps it is the observations that are incorrect. Hubble astronomers soon hope to solve this riddle by taking further measurements to refine their figures. "This is a programme that we know is going to give us some really firm answers in the next three to five years," said Dr Macchetto, one of the 15 European astronomers at the Space Telescope Science Institute. "It will take that time to collect and analyse enough data." Part of the Universe is missing ! Once astronomers know the expansion rate of the Universe they will be one step away from determining its fate. But it will be a big step - for astronomers will have to work out the mass of the Universe and

  4. The International Geophysical Year in Antarctica: Uncommon Collaborations, Unprecedented Results

    ERIC Educational Resources Information Center

    Belanger, Dian Olson

    2004-01-01

    When 1 July 1957 ''dawned'' in the dark of the south polar night, Americans at seven scientific stations scattered across Antarctica officially began systematic, synoptic observations of the air above and ice below. Joining scientists from 11 other countries on the polar continent, they were part of the International Geophysical Year, an 18-month…

  5. [Aortobifemoral prostheses with "0" porosity. Results after 2 years' experience].

    PubMed

    Escudero, J R; Llagostera, S; Riambau, V; Latorre, E; Upegui, L; Pastor, O; Viver, E

    1990-01-01

    During the last years diverse types of Dacron prosthesis without porosity (because to be impregnated by different materials) have appeared. In the presented study, outcomes from three different types of prosthesis (differentiated by the impregnated material) were evaluated and a comparison with classical prosthesis was made.

  6. 2 Years of Science, One-of-a-Kind Results

    ERIC Educational Resources Information Center

    Ashburn, Elyse

    2007-01-01

    Fourteen years ago, Bruce A. Jackson was doing his postdoctoral work at the Boston University School of Medicine and working nights teaching at nearby Roxbury Community College. But his exhausting shuttle between two colleges was about to come to an end. Mr. Jackson, a biochemist, had recently received word from the National Science Foundation…

  7. [Pacemaker implantation in dogs: results of the last 30 years].

    PubMed

    François, L; Chetboul, V; Nicolle, A; Carlos, C; Borenstein, N; Pouchelon, J L

    2004-07-01

    Pacemaker implantation in veterinary practice is still not well known and remains uncommon. However, this technique is the only possible way to cure animals suffering from symptomatic bradycardia whose state does not improve with a medical treatment. In most cases, the use of pacemakers in veterinary medicine leads to the disappearance of the clinical and electrocardiographic signs. This retrospective study concerning the last 30 years draws up an evaluation of the improvements, advantages and drawbacks of this method. Moreover, this study allows the understanding of the evolution of pacemakers' use in veterinary cardiology.

  8. Field Test: Results from the One Year Mission

    NASA Technical Reports Server (NTRS)

    Reschke, M. F.; Kozlovskaya, I. B.; Kofman, I. S.; Tomilovskaya, E. S.; Cerisano, J. M.; Rosenberg, M. J. F.; Bloomberg, J. J.; Stenger, M. B.; Lee, S. M. C.; Laurie, S. S.; Rukavishnikov, I. V.; Fomina, E. V.; Wood, S. J.; Mulavara, A. P.; Feiveson, A. H.; Fisher, E. A.; Phillips, T.; Ribeiro, C.; Taylor, L. C.; Miller, C. A.; Gadd, N. E.; Peters, B. T.; Kitov, V. V.; Lysova, N. Yu; Holden, K. L.; De Dios, Y.

    2017-01-01

    The One Year Mission was designed to aid in determining the effect that extending the duration on orbit aboard the International Space Station (ISS) would have on a number of biological and physiological systems. Two crewmembers were selected to participate in this endeavor, one U.S. On-Orbit Segment (USOS) astronaut and one Russian cosmonaut. The Neuroscience and Cardiovascular and Vision Laboratories at the Johnson Space Center and the Sensory-Motor and Countermeasures Division within the Institute for Biomedical Problems were selected to investigate vestibular, sensorimotor and cardiovascular function with the two long-duration crewmembers using the established methodology developed for the Field Test (FT).

  9. Results of Detailed Hydrologic Characterization Tests - Fiscal Year 2000

    SciTech Connect

    Spane, Frank A.; Thorne, Paul D.; Newcomer, Darrell R.

    2001-05-15

    This report provides the resluts of detailed hydrologic characterization tests conducted within eleven Hanford Site wells during fiscal year 2000. Detailed characterization tests performed included groundwater-flow characterization; barometric response evaluation; slug tests; single-well tracer tests; constant-rate pumping tests; and in-well, vertical flow tests. Hydraulic property estimates obtained from the detailed hydrologic tests include transmissivity; hydraulic conductivity; specific yield; effective porosity; in-well, lateral flow velocity; aquifer-flow velocity; vertical distribution of hydraulic conductivity (within the well-screen section); and in-well, verticla flow velocity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for four sites where detailed well testing was performed.

  10. Two years at Meridiani Planum: Results from the opportunity rover

    USGS Publications Warehouse

    Squyres, S. W.; Knoll, A.H.; Arvidson, R. E.; Clark, B. C.; Grotzinger, J.P.; Jolliff, B.L.; McLennan, S.M.; Tosca, N.; Bell, J.F.; Calvin, W.M.; Farrand, W. H.; Glotch, T.D.; Golombek, M.P.; Herkenhoff, K. E.; Johnson, J. R.; Klingelhofer, G.; McSween, H.Y.; Yen, A. S.

    2006-01-01

    The Mars Exploration Rover Opportunity has spent more than 2 years exploring Meridiani Planum, traveling ???8 kilometers and detecting features that reveal ancient environmental conditions. These include well-developed festoon (trough) cross-lamination formed in flowing liquid water, strata with smaller and more abundant hematite-rich concretions than those seen previously, possible relict "hopper crystals" that might reflect the formation of halite, thick weathering rinds on rock surfaces, resistant fracture fills, and networks of polygonal fractures likely caused by dehydration of sulfate salts. Chemical variations with depth show that the siliciclastic fraction of outcrop rock has undergone substantial chemical alteration from a precursor basaltic composition. Observations from microscopic to orbital scales indicate that ancient Meridiani once had abundant acidic groundwater, arid and oxidizing surface conditions, and occasional liquid flow on the surface.

  11. DOE Radiological Calibrations Intercomparison Program: Results of fiscal year 1987

    SciTech Connect

    Cummings, F.M.; McDonald, J.C.

    1988-06-01

    This report presents the FY 1987 results of the radiological calibrations intercomparison program. The intercomparison operation is discussed, and the equipment is described, particularly the instrument set, the beta source set, and relevant calculations. Solutions to problems and improvements in the program are suggested, and conclusions are then introduced. 9 refs., 3 figs., 8 tabs.

  12. Results from the Australasian Vascular Surgical Audit: the inaugural year.

    PubMed

    Beiles, C Barry; Bourke, Bernie; Thomson, Ian

    2012-03-01

    The Australian and New Zealand Society for Vascular Surgery has incorporated a constitutional change to administer a self-funded compulsory vascular surgery audit since January 2010. This is a bi-national quality assurance activity that captures all procedures performed in both countries. Data is collected at two points in the clinical admission; at operation and at discharge and data entry is via the Internet. Security is stringent and confidentiality is guaranteed by Commonwealth privilege. Data privacy is maximized by encryption. The application is flexible and administered by a dedicated administrator with a help-desk facility. Reports are available to provide real-time feedback of user performance compared with the peer group data in key categories of arterial surgery. A structured hierarchy for data management has been established to assess four main categories of performance: mortality after aortic surgery, stroke and death after carotid surgery, patency and limb salvage after infrainguinal bypass and patency after arteriovenous access for haemodialysis. Data is analysed using risk-adjustment techniques and an algorithm for management of underperformance has been followed. Data validation has been performed. The outcomes in all categories have been of a high standard and correction of erroneous data in a single statistical outlier has negated underperformance. The audit has captured only 65% of the estimated procedures in Australia in the first year, but data quality is good. The feasibility of a complete compulsory bi-national audit has now been established and will be the benchmark for other craft groups in the current environment of accountability.

  13. New catalyst, improved presulfiding result in 4+ year hydrotreater run

    SciTech Connect

    Gorra, F. ); Scribano, G. ); Christensen, P.; Anderson, K.V.; Corsaro, O.G. )

    1993-08-23

    Prompted by decreasing catalyst activity and unit run lengths, an Italian refiner made several modifications to its coker gas oil desulfurization unit equipment, catalyst, and operations. Results of the project include improved catalyst activity at start-of-run, increased unit capacity of end-of-run, and improved plant economics. The paper describes the background of the problem, the process, operational history, catalyst testing, unit modifications, catalyst loading, catalyst service life, and economics.

  14. Results from two years of resistivity monitoring at Cerro Prieto

    SciTech Connect

    Wilt, M.J.; Goldstein, N.E.

    1981-01-01

    Dipole-dipole resistivity measurements for the combined purposes of reservoir delineation and resistivity monitoring were first made at Cerro Prieto in 1978 and have continued on an annual basis since then. Two 20 km long dipole-dipole lines with permanently emplaced electrodes at one kilometer spacings were established over the field area; one of these lines is remeasured annually. Resistivity measurements are taken using a 25 kW generator capable of up to 80A output and a microprocessor controlled signal averaging receiver; this high power-low noise system is capable of highly accurate measurements even at large transmitter-receiver separations. Standard error calculations for collected data indicate errors less than 5% for all points, but 95% confidence intervals show error limits about 2 to 4 times higher. Analysis of collected data indicate little change in the apparent resistivity of the upper 300 m over the field production zone and that in this section measurements are relatively insensitive to the annual rainfall cycle. Apparent resistivity increases were observed over the older producing zone at Cerro Prieto at depths of 1 km and greater. Large zones of decreasing apparent resistivity were observed flanking the zone of increases on both sides. The increase in apparent resistivity in the production region may be due to an increasing fraction of steam in the reservoir resulting from a production related decline in reservoir pressure. Alternatively the increases may be the result of fresh water influx from the Colorado River. The zone of declining resistivity flanking the area of increase may be due to the movement of saline waters into the reservoir region as a result of the pressure decline. Quantitative modeling of observed changes is impractical owing to the high uncertainty in estimating apparent resistivity changes and the nonuniqueness of models.

  15. Nimbus-7 global cloud climatology. II - First year results

    NASA Technical Reports Server (NTRS)

    Stowe, Larry L.; Yeh, H. Y. Michael; Wellemeyer, Charlie G.; Eck, Thomas F.; Kyle, H. Lee

    1989-01-01

    Results are presented on the analysis of the Nimbus-7 satellite data set obtained on regional and seasonal variations in global cloud cover. Four midseason months (April, July, and October 1979 and January 1980) were analyzed for the total cloud amount, the cloud amounts at high, middle, and low altitudes, the cirrus and deep convective clouds, and the cloud and clear-sky 11.5 micron-derived radiances; in addition, noon versus midnight cloud amounts were examined. The Nimbus-7 data are compared with three previously published cloud climatologies, and the differences among these data sets are discussed.

  16. Results of Detailed Hydrologic Characterization Tests - Fiscal Year 1999

    SciTech Connect

    Spane, Frank A.; Thorne, Paul D.; Newcomer, Darrell R.

    2001-01-19

    This report provides the results of detailed hydrologic characterization tests conducted within newly constructed Hanford Site wells during FY 1999. Detailed characterization tests performed during FY 1999 included: groundwater flow characterization, barometric response evaluation, slug tests, single-well tracer tests, constant-rate pumping tests, and in-well vertical flow tests. Hydraulic property estimates obtained from the detailed hydrologic tests include: transmissivity, hydraulic conductivity, specific yield, effective porosity, in-well lateral flow velocity, aquifer flow velocity, vertical distribution of hydraulic conductivity (within the well-screen section) and in-well vertical flow velocity. In addition, local groundwater flow characteristics (i.e., hydraulic gradient and flow direction) were determined for four sites where detailed well testing was performed.

  17. Five-year ALARA review of dosimetry results :

    SciTech Connect

    Paulus, Luke R.

    2013-08-01

    A review of personnel dosimetry (external and internal) and environmental monitoring results from 1 January 2008 through 31 December 2012 performed at Sandia National Laboratories, New Mexico was conducted to demonstrate that radiation protection methods used are compliant with regulatory limits and conform with the ALARA philosophy. ALARA is the philosophical approach to radiation protection by managing and controlling radiation exposures (individual and collective) to the work force and to the general public to levels that are As Low As is Reasonably Achievable taking social, technical, economic, practical, and public policy considerations into account. ALARA is not a dose limit but a process which has the objective of attaining doses as far below applicable dose limits As Low As is Reasonably Achievable.

  18. Murchison Widefield Array (MWA) - 1st Year Science Results

    NASA Astrophysics Data System (ADS)

    Bowman, Judd D.; Murchison Widefield Array (MWA) Collaboration

    2015-01-01

    The Murchison Widefield Array (MWA) is the first radio telescope in the Southern Hemisphere designed specifically to explore the astronomical sky between 80 and 300 MHz with arcminute angular resolution and high survey efficiency. The MWA has the goal of detecting 21 cm emission from neutral hydrogen during the reionization epoch. It provides unique opportunities for studies of our Galactic environment, including ISM turbulence, magnetic fields, cosmic rays, and supernova remnants, as well as extragalactic surveys, time-domain astrophysics, and solar imaging and space weather. Early results will be reported highlighting the capabilities of the instrument. Featured science will include initial reionization analysis, preliminary searches for exoplanets and variable sources, spectral properties of radio sources, ionospheric fluctuations, and solar imaging.

  19. DOE radiological calibrations intercomparison program: Results of fiscal year 1988

    SciTech Connect

    Cummings, F.M.; McDonald, J.C.; Murphy, M.K.

    1989-08-01

    Calibration measurements for personnel dosimetry purposes must be both accurate and consistent with national standards. In order to satisfy these requirements, the following methods are usually employed. In one case, a radiation source is sent to the National Institute of Standards and Technology (NIST), formerly the National Bureau of Standards, for calibration and is returned to the laboratory to be used as a local standard. Another method involves the calibration of an instrument, such as an ionization chamber, by NIST. After calibration, this instrument is then used to measure the exposure rate delivered by radiation sources at the laboratory. Such calibrations by NIST are essential, but they do not provide a complete check on the quality of the calibrations that are carried out by the individual laboratory. Additional measurements are necessary to assure the quality of such measurements. When laboratory staff are asked to carry our measurements with calibrated instruments and report results for evaluation, they are participating in a measurement quality assurance (MQA) program. Such a program tests not only the quality of the equipment but also the ability of the staff to correctly use and interpret the results obtained with the equipment. The NIST operates an MQA program with a selected number of calibration laboratories. Pacific Northwest Laboratory (PNL) participates in this MQA program even though NIST test only x-ray and gamma-ray measurements. The US Department of Energy (DOE) intercomparison program was designed specifically to include x-ray, gamma-ray, beta, and neutron calibrations for personnel dosimetry purposes. This program serves a need that is not being met by NIST, and it provides documentation of the accuracy and uniformity of the radiological calibrations carried out in DOE facilities. 7 refs., 3 figs., 6 tabs.

  20. SMART-1 SPEDE: Results and Legacy after 10 Years

    NASA Astrophysics Data System (ADS)

    Schmidt, Walter; Mälkki, Anssi

    2014-05-01

    sensor area treatment was optimized for SPEDE and used in all subsequent Langmuir probe designs of IRF/Uppsala. The algorithm implemented inside the SPEDE on-board software to analyze the plasma wave measurements was optimized during the SMART-1 mission and later uplinked to the ESA Rosetta spacecraft lander Philae, where it is now used to analyze and compress the data of the permittivity probe, also used as a plasma wave monitor with W.Schmidt as PI. The experience gained from the FPGA-implementation of a self-developed processor was later used in preparation of ESA's ExoMars 2016 pressure sensor controller and the Swedish plasma instrument LINA for a Russian Lunar mission as well as for the ESA JUICE mission to the Jupiter system. Reference: [1] Mälkki, A., Schmidt, W., Laakso, H., Grard, R., Escoubet, C.P., Wahlund, J.-E., Blomberg, L., Marklund, G. and Johlander, B., 2003: The SPEDE experiment on SMART-1: Instrument, mission, and science objectives. Geophysical Research Abstracts, Vol 5., 10004, 2003. [2] Mälkki, A., Schmidt, W., Laakso, H., Johlander, B., Wahlund, J.E., Blomberg, L., Marklund, G., Grard, R., Escoubet, C.P. and Lebreton, J.P., 2004: First results from SMART-1/ SPEDE plasma experiment. European Geophysical Union EGU-2004, EGU04-A-02543. Invited oral presentation [3] Mälkki, A., Schmidt, W., Genzer, M., Merikallio, S., Laakso, H., Gonzales del Amo, J., Estublier, D., Gengembre, E., Hilgers, A., Capacci, M., Koppel, C. and Tajmar, M., 2005: Spacecraft-plasma interaction analysis using data from SPEDE on SMART-1. 10th Scientific Assembly of IAGA, Toulouse, France, July 2005, paper IAGA2005-A-01401 [4] Mälkki, A., Schmidt, W., Kallio, E. and Merikallio, S., 2006: Interaction of Solar Wind With the Moon: Results From Hybrid Modeling and the SPEDE Instrument on SMART-1. Geophysical Research Abstracts, Vol. 8, 07632, 2006 [5] M.Backrud, 2007: Evaluation of the SPEDE instrument on SMART-1, Royal Institute of Technology (KTH) Report - TRITA-EE 2007:023

  1. Beating the Odds: Assessment Results from the 2006-2007 School Year. Individual District Results

    ERIC Educational Resources Information Center

    Council of the Great City Schools, 2008

    2008-01-01

    This report includes quantitative information by individual urban school district for the 2006-2007 school year. Data includes: (1) Total Students; (2) Free/Reduced Price Lunch Eligible Students; (3) Students with Individual Educational Plans; (4) English Language Learners; (5) American Indian/Alaskan Native Students; (6) Asian/Pacific Islander…

  2. Five-year results of coronary bypass grafting for patients older than 70 years: role of internal mammary artery.

    PubMed

    Azariades, M; Fessler, C L; Floten, H S; Starr, A

    1990-12-01

    Despite numerous references to the superiority of the internal mammary artery (IMA) over the saphenous vein for myocardial revascularization, its role in the elderly is still in question. From January 1984 through December 1988, 1,081 patients older than 70 years (mean age, 74.9 years) underwent bypass grafting, 354 (33%) receiving left IMA grafts based on the surgeon's preference and 727 (67%) receiving vein grafts only. Selection bias resulted in a higher incidence of known risk factors (such as cardiomegaly, arrhythmias, left ventricular failure, wall motion abnormalities, and preoperative combined New York Heart Association/Canadian Cardiovascular Association functional class IV) in patients in whom the IMA was not used. However, unstable angina, acute myocardial infarction, left ventricular dysfunction, and left main disease were not contraindications for using IMA grafts. The operative mortality rate was significantly lower in IMA patients (2.8% versus 7.6%). The actuarial 5-year survival rate (standard error) was higher in patients with IMA grafts, 89% (3%) versus 78% (2%), and postoperative functional class improved to a greater extent in IMA patients (87% of patients were in classes I and II). Arrhythmias and myocardial infarction were significant causes of late death only in patients with vein grafts. When patients are older than 70 years, patient selection factors clearly play an important role in the differential results between patients in whom the IMA is used and patients in whom vein grafts are used. As in younger patients, excellent results can be achieved in the elderly.

  3. Open Surgical Treatment for Femoroacetabular Impingement in Patients over Thirty Years: Two Years Follow-up Results

    PubMed Central

    2015-01-01

    Purpose We report short term results of open surgical treatment for symptomatic femoroacetabular impingement (FAI) in patients over the age of 30 years. Materials and Methods Between May 2011 and June 2012, thirteen FAI hips (11 patients) with hip pain persisting longer than 6 months were treated by either surgical hip dislocation (SHD) or anterior mini-open. They were followed up for longer than 2 years. The 11 patients included 7 females and 4 males with a mean age of 45 (range, 33-60) years. They were clinically evaluated for modified Harris hip score (MHHS) and University of California at Los Angeles (UCLA) activity level. Their lateral center-edge angle, acetabular index, and alpha angle were measured and compared. Results Acetabuloplasties were performed for seven cases. Femoral osteochondroplasty was performed for all thirteen cases. At minimum follow-up of two year (range, 24-29 months), all patients had substantial relief in preoperative pain with improvement in range of motion. The median MHHS was significantly (P<0.05) improved from 61 points preoperatively to 87 points at the last follow-up. The median UCLA activity level was 7 (range, 5-8) at last follow-up. Radiological indices improved. Two cases showed mild residual pain attributable to adhesion between capsule and reshaped femoral head-neck area. Conclusion Open surgical treatment of FAI was a reliable and effective treatment method in symptomatic FAIs for patients over the age of 30 years without advanced arthritic change of hip joint at short term follow-up. PMID:27536632

  4. Fifteen Years of Collaborative Innovation and Achievement: NASA Nebraska Space Grant Consortium 15-Year Program Performance and Results Report

    NASA Technical Reports Server (NTRS)

    Schaaf, Michaela M. (Editor); Bowen, Brent D.; Fink, Mary M.; Nickerson, Jocelyn S.; Avery Shelly; Calamaio, Caprice; Carstenson, Larry; Dugan, James; Farr, Lynne; Farritor, Shane

    2003-01-01

    This 15-year evaluation serves as a summary document highlighting the numerous and complete successes of the Nebraska Space Grant Program. Innovation has been highlighted through significant new endeavors during this 5-year period, such as placement of students and faculty at NASA Centers and the expansion of NSGC Native American Outreach Programs. While the last national program evaluation resulted in Nebraska s ranking as the top Capability Enhancement Consortium, and 5th best overall, Nebraska felt there was room for significant growth and development. This has been validated through the recent competitive attainment of Designated Grant status and has allowed for the exploration of new initiatives, as well as the expansion of already successful programs. A comprehensive strategic planning effort has involved all Nebraska representative entities and has guided Nebraska Space Grant through the evaluation period, providing a basis for continual advancement. Nebraska rigorously employs evaluation techniques to ensure that stated outcomes and metrics are achieved and that weaknesses are identified and corrected. With this coordinated approach, Nebraska expects that the next 5 years will yield new opportunities for significant achievement. Nebraska Space Grant will embrace new national endeavors, including the integration of Pender Public Schools -Nebraska s NASA Explorer School, geospatial initiatives, and the National Student Satellite Program.

  5. Fifteen Years of Collaborative Innovation and Achievement: NASA Nebraska Space Grant Consortium 15-Year Program Performance and Results Report

    NASA Technical Reports Server (NTRS)

    Schaaf, Michaela M.; Bowen, Brent D.; Fink, Mary M.; Nickerson, Jocelyn S.; Avery, Shelly; Carstenson, Larry; Dugan, James; Farritor, Shane; Joyce, James; Rebrovich, Barb

    2003-01-01

    Condensing five years of significant work into a brief narrative fitting PPR requirements gave the affiliates of the Nebraska Space Grant a valuable chance for reflection. Achievements of Space Grant in Nebraska were judiciously chosen for this document that best illustrate the resultant synergism of this consortium, keeping in mind that these examples are only a representation of greater activity throughout the state. Following are highlights of many of the finer and personal achievements for Nebraska Space Grant. The Consortium welcomes inquiries to elaborate on any of these accomplishments.

  6. [Tibial valgization osteotomy in gonarthrosis with or without chondrocalcinosis. Results after 5 years].

    PubMed

    Job-Deslandre, C; Languepin, A; Benvenuto, M; Menkès, C J

    1991-01-01

    The authors compare the results of valgisation tibial osteotomies in osteoarthrosis of the knee (146 cases) and osteoarthrosis of the knee with chondrocalcinosis (94 cases). The two groups were identical in terms of age, but differed by sex ratio (female predominance in CCA) and the initial radiological stage (more advanced forms in the CCA group). Results differed after the second year and reached significantly different values at 5 years (73% in knee osteoarthrosis as against 34% good clinical results in chondrocalcinosis). Study of two groups of patients paired for age, sex, weight and radiological stage showed that results at 5 years were significantly less good in the CCA group. These results are discussed and compared with those in the 1990 literature.

  7. Outdoor transmission measurement at 26 GHz: Results of a 4 year trial in Prague

    NASA Astrophysics Data System (ADS)

    Thorvaldsen, Per; Henne, Ingvar

    2016-05-01

    This paper presents the results from a field trial that was performed during a 4 year period on a 5.5 km long radio link path operating at 26 GHz in Prague. The purpose was to investigate the amount of attenuation due to precipitation and its yearly variations. The attenuation of the radio link signal and the rain rate were measured. The measured attenuation results are compared to the models given by the International Telecommunication Union (ITU). The propagation measurements show large yearly variations due to variability in rain rate from one year to another. The measured results are in agreement with the ITU long-term statistical rain attenuation model if the measured rain rate for the individual year is used. For the worst year the number of fades, the fade duration, the fade speed, the worst month statistics, and the polarization correlation are presented. The measurements presented will add to the current knowledge of fading due to precipitation, and some of the results, such as the fade duration distributions, are new knowledge.

  8. BARIATRIC SURGERY IN THE ELDERLY: RESULTS OF A MEAN FOLLOW-UP OF FIVE YEARS

    PubMed Central

    PAJECKI, Denis; SANTO, Marco Aurelio; JOAQUIM, Henrique Dametto Giroud; MORITA, Flavio; RICCIOPPO, Daniel; de CLEVA, Roberto; CECCONELLO, Ivan

    2015-01-01

    Background : Surgical treatment of obesity in the elderly, particularly over 65, remains controversial; it is explained by the increased surgical risk or the lack of data demonstrating its long-term benefit. Few studies have evaluated the clinical effects of bariatric surgery in this population. Aim : To evaluate the results of surgical treatment of obesity in patients over 60 years, followed for an average period of five years. Method : This was a retrospective study evaluating 46 patients, 60 years or older, who underwent surgical treatment of obesity, by conventional gastric bypass technique (laparotomy). The average age was 64 years (60-71), mean BMI of 49.6 kg/m2 (38-66), mean follow-up of 5.9 years; 91% of patients were hypertensive, 56% diabetics and 39% had dyslipidemia. Results : The incidence of complications (major and minor) in patients under 65 years was 26% and over 65 years 37% (p=0.002). There were no deaths in the group with less than 65 years and there were two deaths (12.5%) over 65 years. The average loss of overweight over 65 years or less was 72% vs 68% (p=0.56). There was total control of the diabetes mellitus in 77% and partial in 23%, with no difference between groups. There was improvement in arterial hypertension in 56% of patients, also no difference between groups. The average LDL levels did not differ between the pre and postoperative (106 mg/dl to 102 mg/dl), an increase of HDL (56 mg/dl to 68 mg/dL) and reduced triglyceride levels (136 mg/dl to 109 mg/dl). There was no statistical difference in the variation of the cholesterol fractions and triglycerides between the groups. Two patients in the group with less than 65 years died in late follow-up, of brain tumor and pneumonia, three and five years after bariatric surgery, respectively. Conclusions : Surgical morbidity and mortality were higher in patients over 65 years, and this group had the same benefits observed in patients lower 65 years for weight loss and comorbidities control

  9. [Long-term (33 years) result of revascularization of subtotally amputated upper arm].

    PubMed

    Kaczmarzyk, Janusz; Kocieba, Ryszard; Jabłecki, Jerzy

    2008-01-01

    Replantations and revascularizations on the level of the arm are performed in the smallest number. The achieved functional results are poor. The paper presents a result achieved in a patient who sustained an avulsion amputation of an upper arm in the year 1974. The first long-term control was made 11 years after the revascularization of the limb which rated the result as III acc. to Chen's score system. The patient was steadily highly motivated for hand rehabilitation process. The second control performed 33 years after the accident proved the increase of sensibility, muscle strength as well as the range of movements. The result was up-graded as II (good). No degenerative changes in hand bones of mutilated hand were found.

  10. High Remission Rate of Chronic Immune Thrombocytopenia in Children: Result of 20-Year Follow-Up

    PubMed Central

    Kim, Chae Young; Lee, Eun Hye

    2016-01-01

    Purpose This study examined the outcomes of children with chronic immune thrombocytopenia (ITP). Materials and Methods We retrospectively analyzed the medical records of all patients diagnosed with ITP from January 1992 to December 2011 at our institution. Results A total of 128 patients (64%) satisfied the criteria for newly diagnosed ITP, 31 (15%) for persistent ITP, and 41 (21%) for chronic ITP. The median age at diagnosis was 4.5 years (range, 1 month to 18 years). The median platelet count at diagnosis was 32×109/L. A comparison of the initial treatment data from 2001 to 2011 with those from 1992 to 2000 showed that the number of bone marrow examinations decreased, whereas observation increased. Chronic ITP presented at an older age than newly diagnosed and persistent ITP (6.6 years vs. 3.8 years vs. 4.1 years, respectively); however, the difference did not reach statistical significance (p=0.17). The probability of complete remission of chronic ITP was 50% and 76% at 2 and 5 years after diagnosis, respectively. Patients aged <1 year at diagnosis had a significantly better prognosis than did older patients (hazard ratio, 3.86; p=0.02). Conclusion Children with chronic ITP showed a high remission rate after long-term follow-up. This study suggests that invasive treatments such as splenectomy in children with chronic ITP can be delayed for 4 to 5 years if thrombocytopenia and therapeutic medication do not affect the quality of life. PMID:26632392

  11. Three years of retrospective evaluation of skin biopsy results in childhood

    PubMed Central

    Ozkanli, Seyma; Zemheri, Ebru; Zindanci, Ilkin; Kuru, Burce; Zenginkinet, Tulay; Karadag, Ayse Serap

    2015-01-01

    OBJECTIVE: In our study, we aimed to evaluate retrospectively histopathological diagnoses of children based on their skin biopsies, and determine the prevalence of the disease in question. METHODS: Among patients who applied to Medeniyet University Goztepe Training and Research Hospital between January 2011 and February 2014, we retrospectively evaluated demographic data and histopathological diagnoses of patients aged between 0-17 years whose skin punch biopsy samples were obtained. RESULTS: The study population (n=566) with skin biopsy results consisted of 287 (50.7%) male, and 279 (49.2%) female patients with a mean age of 10.04±4.84 years. Biopsy materials were obtained from the various age groups as follows: 0-2 years, n=31 (5.4%); 3-5 years, n=67 (11.8%) 6-11 years, n=165 (29.1%), and 12-17 years, n=303 (53.5%). Among all age groups, we took biopsies mostly from patients with noninfectious erythematous squamous (24%) and vascular (21.2%) diseases. The determined histopathological diagnoses were leukocytoclasis vasculitis (18.9%), psoriasis (7.4%), melanocytic nevus (5.4%), and contact dermatitis (5.1%) respectively. CONCLUSION: We determined that skin punch biopsy examinations were done most frequently during adolescence and are mostly necessary for diagnosis of erythematous squamous and vascular diseases. If clinical evidence-based prevalence studies are supported with histopathological data, more significant results can be obtained. PMID:28058339

  12. Results.

    ERIC Educational Resources Information Center

    Zemsky, Robert; Shaman, Susan; Shapiro, Daniel B.

    2001-01-01

    Describes the Collegiate Results Instrument (CRI), which measures a range of collegiate outcomes for alumni 6 years after graduation. The CRI was designed to target alumni from institutions across market segments and assess their values, abilities, work skills, occupations, and pursuit of lifelong learning. (EV)

  13. Visual function and car driving: longitudinal results 5 years after cataract surgery in a population

    PubMed Central

    Mönestam, E; Lundquist, B; Wachtmeister, L

    2005-01-01

    Aims: To determine visual function in drivers who had cataract surgery 5 years previously, and to analyse longitudinal data, by comparing preoperative and postoperative changes in subjective driving ability and objective visual function. Methods: All patients (810) who underwent cataract surgery, during a 1 year period, were prospectively studied. Data regarding present driving status were collected from self administered questionnaires and visual acuity (VA) data were measured before and after surgery. All patients who were alive 5 years later were invited to participate with a new eye examination and questionnaire. Results: Before surgery 36 active drivers (16%) did not fulfil the visual requirements for driving; with improved glasses this number could be reduced to 24 (11%). 5 years after surgery, the corresponding figures were 5% and 3% (5/174), respectively. Before surgery 50% stated visual difficulties while driving in daylight and 79% in darkness. A few months and 5 years after surgery the corresponding figures were 6% and 5%, respectively, for daytime driving and 34% and 44%, respectively, for night-time driving. Conclusions: Long term results regarding cataract surgery in car drivers are beneficial. 5 years after surgery only a few patients drove not fulfilling the requirements, but there were a larger proportion of patients with problems driving in darkness compared with a few months after surgery. PMID:15774924

  14. Aortic valve replacement with the Cardioprotese Premium bovine pericardium bioprosthesis: four-year clinical results

    PubMed Central

    Farias, Fábio Rocha; da Costa, Francisco Diniz Affonso; Balbi Filho, Eduardo Mendel; Fornazari, Daniele de Fátima; Collatusso, Claudinei; Ferreira, Andreia Dumsch de Aragon; Lopes, Sergio Veiga; Fernandes, Tadeu Augusto

    2012-01-01

    OBJECTIVES This study reports the initial clinical and echocardiographic results of the Premium bioprosthetic aortic valve up to 4 years of follow-up. METHODS Between October 2007 and July 2011, 121 consecutive patients were submitted for aortic valve replacement with the Premium bioprosthetic valve. The mean age was 68 ± 9 years and 64 patients were males. The patients were periodically evaluated by clinical and echocardiographic examinations. The mean follow-up was 21 months (min = 2, max = 48), yielding 217 patients/year for the analysis. RESULTS The hospital mortality was 8%. Late survival at 3 years was 89% (95% CI: 81.9–93.3%), and 80% of the patients were in NYHA functional class I/II. The rates of valve-related complications were low, with a linearized incidence of 0.9%/100 patients/year for thromboembolic complications, 0% for haemorrhagic events and 0.9%/100 patients/year of bacterial endocarditis. There was no case of primary structural valve dysfunction. The mean effective orifice area was 1.61 ± 0.45 cm2; mean gradient 13 ± 5 mmHg and peak gradient 22 ± 9 mmHg. Significant patient–prosthesis mismatch was found in only 11% of the cases. CONCLUSIONS The Premium bioprosthetic aortic valve demonstrated very satisfactory clinical and echocardiographic results up to 4 years, similar to other commercially available, third-generation bioprosthetic valves. PMID:22588029

  15. Propellant/material compatibility program and results: Ten-year milestones

    NASA Technical Reports Server (NTRS)

    Moran, C.; Bjorkland, R.

    1982-01-01

    The analyses and results of a test program to establish the effects of long term (10 years or more) contact of materials with earth-storable propellants for the purpose of designing chemical propulsion system components which are used for current as well as future planetary spacecraft are described. The period from the publication of JPL TM 33-779 IN 1976 through the testing accomplished in 1981 is covered. The following propellants are reported herein: hydrazine, monomethylhydrazine and nitrogen tetroxide. Materials included the following: aluminum alloys, corrosion resistant steels and a titanium alloy. The results of the testing of more than 80 specimens are included. Material ratings relative to the ten year milepost were assigned. Some evidence of propellant decomposition was found. Titanium is rated as acceptable for ten year applications. Aluminum and stainless steel alloys are also rated as acceptable with few restrictions.

  16. First-Year Results of an Obesity Prevention Program at The Dow Chemical Company

    PubMed Central

    Goetzel, Ron Z.; Baker, Kristin M.; Short, Meghan E.; Pei, Xiaofei; Ozminkowski, Ronald J.; Wang, Shaohung; Bowen, Jennie D.; Roemer, Enid C.; Craun, Beth A.; Tully, Karen J.; Baase, Catherine M.

    2010-01-01

    Objective To examine first-year results from a workplace environmental obesity prevention program at The Dow Chemical Company. Methods A quasi-experimental cohort study was conducted among employees at nine treatment worksites (n=8,013) who received environmental weight management interventions and three control worksites (n=2,269). Changes in employees’ weight, body mass index (BMI), and other health risks were examined using chi-square and t-tests. Results After one year, a modest treatment effect was observed for weight and BMI largely because the control group subjects gained weight; however, no effect was observed for overweight and obesity prevalence. Other risk factors (tobacco use, high blood pressure, and systolic and diastolic blood pressure values) decreased significantly, although blood glucose (high risk prevalence and values) increased. Conclusions Environmental changes to the workplace can achieve modest improvements in employees’ health risks, including weight and BMI measures, in one year. PMID:19209033

  17. Ten years of photonics education at the college level in Ontario: results and by-products

    NASA Astrophysics Data System (ADS)

    Nantel, Marc

    2010-08-01

    In 2000, there was no way for an Ontario student to obtain a credential in optics, laser or photonics without going through graduate school. This was in, arguably, the world-leading jurisdiction in photonics-enabled telecommunications industry. To alleviate this problem and supply the job market with highly-qualified people in the field of optics and photonics, the Ontario Centres of Excellence - then as Photonics Research Ontario - partnered with Algonquin College (Ottawa) and Niagara College (Welland) to establish over the past decade a suite of programs: a 1-year Certificate in Advanced Lasers, a 2-year Diploma for Photonics Engineering Technician, a 3-year Diploma for Photonics Engineering Technologists and a 4-year Bachelor of Applied Technology - Photonics. Much has been learnt along the way - the crucial need for industrial partner and government support, for example - and many course corrections had to be made (telecom bust, anyone?). The author will share the results of this 10-year journey so far, the lessons learnt, and a view to the next ten years for these programs and photonics education in Ontario in general.

  18. The five-year radiological results of the uncemented Oxford medial compartment knee arthroplasty.

    PubMed

    Hooper, N; Snell, D; Hooper, G; Maxwell, R; Frampton, C

    2015-10-01

    This study reports on the first 150 consecutive Oxford cementless unicompartmental knee arthroplasties (UKA) performed in an independent centre (126 patients). All eligible patients had functional scores (Oxford knee score and high activity arthroplasty score) recorded pre-operatively and at two- and five-years of follow-up. Fluoroscopically aligned radiographs were taken at five years and analysed for any evidence of radiolucent lines (RLLs), subsidence or loosening. The mean age of the cohort was 63.6 years (39 to 86) with 81 (53.1%) males. Excellent functional scores were maintained at five years and there were no progressive RLLs demonstrated on radiographs. Two patients underwent revision to a total knee arthroplasty giving a revision rate of 0.23/100 (95% confidence interval 0.03 to 0.84) component years with overall component survivorship of 98.7% at five years. There were a further four patients who underwent further surgery on the same knee, two underwent bearing exchanges for dislocation and two underwent lateral UKAs for disease progression. This was a marked improvement from other UKAs reported in New Zealand Joint Registry data and supports the designing centre's early results.

  19. Learning Benefits of Self-Controlled Knowledge of Results in 10-Year-Old Children

    ERIC Educational Resources Information Center

    Chiviacowsky, Suzete; Wulf, Gabriele; Laroque de Medeiros, Franklin; Kaefer, Angelica; Tani, Go

    2008-01-01

    The purpose of the present study was to examine whether the learning benefits of self-controlled knowledge of results (KR) would generalize to children. Specifically, the authors chose 10-year-old children representative of late childhood. The authors used a task that required the children to toss beanbags at a target. One group received KR…

  20. Research Results: Mobility of BC Transfer Students. Fall 2007 to Calendar Year 2008

    ERIC Educational Resources Information Center

    Heslop, Joanne

    2009-01-01

    This newsletter highlights research results on the Mobility of Transfer Students (MTS), a branch of research conducted under the auspices of the Student Transitions Project (STP). In this annual study, students enrolled in the Fall of 2007 in BC colleges, university colleges, and institutes were followed into calendar year 2008 to identify those…

  1. Organic methods for control of pecan weevil: Results of the first year's field trials

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Integrated organic tactics for control of pecan weevil were investigated in large field plot tests. The experiment was conducted at two locations: USDA-ARS Research Lab in Byron, GA and Cleveland farms in Fort Valley, GA. Results from the first year field trials indicated that organic tactics for ...

  2. Podcast Lectures as a Primary Teaching Technology: Results of a One-Year Trial

    ERIC Educational Resources Information Center

    Taylor, Mark Zachary

    2009-01-01

    How useful are podcasts in the political science classroom? Some educators argue that podcasts will revolutionize education; others are less convinced. However, to date, the evidence on podcasts has been slim. This article reports the results of a year-long trial using podcasts to aid in teaching political science to undergraduates at a research…

  3. After One Year, Mixed Results from Push for Neighborhood Schools. Research Brief. Volume 90, Number 4

    ERIC Educational Resources Information Center

    Public Policy Forum, 2002

    2002-01-01

    One school year after implementation of the Neighborhood Schools Initiative (NS), more Milwaukee Public School (MPS) district schools enroll more neighborhood students, although the increase in neighborhood enrollment is not the result of capacity-building; fewer schools have the capacity to enroll all their neighborhood students than two years…

  4. Incredible Years Program Tailored to Parents of Preschoolers with Autism: Pilot Results

    ERIC Educational Resources Information Center

    Dababnah, Sarah; Parish, Susan L.

    2016-01-01

    Objective: This article reports on the acceptability and results from an evaluation of an empirically supported practice, The Incredible Years, tailored to parents of children with autism spectrum disorder (ASD). Methods: Two groups of parents (N = 17) participated in a mixed methods test with no comparison group of the 15-week intervention. Data…

  5. Changes in weight over the school year and summer vacation: Results of a 5-year longitudinal study

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Evidence suggests that children gain more weight during the summer months compared with the school year. In order to further examine the impact of the school and summer environment on children's weight, we conducted a 5-year longitudinal study examining changes in standardized BMI (zBMI) of students...

  6. Changes in weight over the school year and summer vacation: Results of a 5-year longitudinal study

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Some evidence suggests that children have relatively higher increases in weight during the summer months compared to the school year. In order to further examine the impact of the school and summer environment on children's weight, we conducted a 5-year longitudinal study examining changes in standa...

  7. Changes in Weight over the School Year and Summer Vacation: Results of a 5-Year Longitudinal Study

    ERIC Educational Resources Information Center

    Moreno, Jennette P.; Johnston, Craig A.; Woehler, Deborah

    2013-01-01

    Background: Evidence suggests that children gain more weight during the summer months compared with the school year. To examine the impact of the school and summer environment on children's weight further, we conducted a 5-year longitudinal study examining changes in standardized BMI (zBMI) of students entering kindergarten. Methods: Heights and…

  8. [Psychophysiological indicators for children using mobile phones. Communication 2. Results of four-year monitoring].

    PubMed

    Khorseva, N I; Grigor'ev, Iu G; Gorbunova, N V

    2011-01-01

    This study submits the results of a four-year monitoring of a complex diagnostics of the psychophysiological indicators for 196 children aged 7 to 12 years old: 147 of them are child users of mobile communication (test group) and 49 are in the control group. We have identified the following major trends of the psychophysiological indicators for child users of mobile communication: an increased number of phonemic perception disorders, abatement of efficiency, reduced indicators for the arbitrary and semantic memory, an increased fatigue. A steady decline of the parameters from high values to bottom standards has been found.

  9. Deep Inelastic Scattering results from the first year of HERA operation

    SciTech Connect

    Magill, S.R.

    1993-12-31

    The first year of operation of the HERA electron-proton collider has resulted in Deep Inelastic Scattering (DIS) Physics results from both the H1 and ZEUS experiments. Reported here are the H1 and ZEUS measurements of the proton structure function F{sub 2} at higher Q{sup 2} and lower x than previously reported from fixed target experiments. Also included are the results of QCD studies on hadronic final states and jets, and the observation of high Q{sup 2} charged current events from both experiments. Finally, the observation of events with large rapidity gaps by the ZEUS collaboration is also reported.

  10. [15 years' results in the treatment of differentiated thyroid carcinoma in a region of endemic goiter].

    PubMed

    Perinetti, H A; Staneloni, L N; Vitale, R

    1990-01-01

    We have evaluated the results of differentiated thyroid carcinoma treatment after 15 years of follow up. The group consisted of 120 cases of papillary type and 144 cases of follicular type; the mean age of the patients was 38.2 years for papillary and 46.5 for the follicular. The ratio men/women was 1/4 for the papillary and 1/3.2 for the follicular. The prognostic factors evaluated included: a) histologic types according to WHO classification, b) clinical stage, c) age and d) sex. The staging of the disease followed the classification suggested by Smendal, stage I: intraglandular disease; stage II: regional lymph node metastases; stage III: invasion of other tissues in the neck or mediastinum and stage IV: distant metastases. The basic treatment was surgery with the use of 131I and thyroid hormone. The results were statistically analyzed with the conventional life table method or chi square. At 15 years the overall survival was 84 +/- 4% for the papillary type and 66 +/- 9% for the follicular type (p = 0.01) (Fig. 1). The patients treated in stage I had a survival of 90 +/- 5%, significantly higher than those in stage II (53 +/- 8%), p less than 0.03. In stage III and IV the small number of patients made it difficult to interpret the results statistically (Fig. 2). The age of the patients appears to be another prognostic factor. The group under 40 years had 85 +/- 5% of survival compared to 59 +/- 4% over 40 years, p less than 0.01 (Fig. 3).(ABSTRACT TRUNCATED AT 250 WORDS)

  11. Video game addiction and college performance among males: results from a 1 year longitudinal study.

    PubMed

    Schmitt, Zachary L; Livingston, Michael G

    2015-01-01

    This study explored the pattern of video game usage and video game addiction among male college students and examined how video game addiction was related to expectations of college engagement, college grade point average (GPA), and on-campus drug and alcohol violations. Participants were 477 male, first year students at a liberal arts college. In the week before the start of classes, participants were given two surveys: one of expected college engagement, and the second of video game usage, including a measure of video game addiction. Results suggested that video game addiction is (a) negatively correlated with expected college engagement, (b) negatively correlated with college GPA, even when controlling for high school GPA, and (c) negatively correlated with drug and alcohol violations that occurred during the first year in college. Results are discussed in terms of implications for male students' engagement and success in college, and in terms of the construct validity of video game addiction.

  12. Evaluation of the management of Hr-HPV+/PapTest- women: results at 1-year recall.

    PubMed

    Chiappetta, Caterina; Puggioni, Chiara; Lendaro, Eugenio; Cacciotti, Jessica; Zaralli, Roberto; Migliore, Giovanna; Bellardini, Paola; Petrozza, Vincenzo; Della Rocca, Carlo; Di Cristofano, Claudio

    2015-01-01

    With cervical cancer screening the choice of 1-year as a period of follow-up in positive high-risk HPV women without cytological lesions is still under discussion. We evaluated the management of these women and the role of HPV genotyping test. We did a cervical cancer screening study of women aged 35-64 with primary high-risk HPV test. Women positive for high-risk HPV with negative cytology were followed-up after 1 year. In this study we selected women with high-risk HPV+/PapTest- resulted high-risk HPV+ at recall and performed the PapTest and HPV genotyping test. The detection rate of squamous high grade (CIN2+) relative to the total screened cohort was 2.1‰, and it was 0.2‰ at the 1-year recall. The colposcopy performed in women referred at the 1-year recall accounted for 48.8% of the total (baseline + 1-year recall), and 84.3% of these women had no cytological lesions. The most frequent hr-HPV genotype detected was HPV16 and 66.7% of co-infections were due to HPV16 and HPV18. 54.5% of women presented a persistent infection at 1-year recall with the same HPV subtype, 50% of persistent infections was due to HPV16 and 16.7% of these were determined to be CIN2+ histological lesions. Our data show that it may be useful to extend the period of follow-up for women hr-HPV+/PapTest- so as to reduce the number of unnecessary colposcopies due to the transitory infections and that the genotyping test could help to identify the persistent infections in which HPV16 is involved.

  13. XEN Glaucoma Implant with Mitomycin C 1-Year Follow-Up: Result and Complications

    PubMed Central

    Bilgic, Alper; Eltanamly, Rasha

    2017-01-01

    Purpose. To evaluate gel microstent (XEN, Aquesys, Inc) for treatment of primary open angle glaucoma (POAG). Methods. In this prospective interventional study, 13 eyes with POAG underwent XEN implantation with subconjunctival mitomycin-C. Of those eyes, 3 were pseudophakic and 10 underwent simultaneous phacoemulsification and XEN. Patients had uncontrolled IOP, had intolerance to therapy, or had maximal therapy but undergoing cataract extraction. Follow-up visits included IOP, number of medications, vision, and complications and lasted for 1 year. Complete success was defined as IOP reduction ≥20% from preoperative baseline at 1 year without any glaucoma medications while partial success as IOP reduction of ≥20% at 1 year with medications. Results. IOP dropped from 16 ± 4 mmHg pre-op to 9 ± 5, 11 ± 6, 12 ± 5, 12 ± 4, and 12 ± 3 mmHg at 1 week, 1, 3, 6, and 12 months (p = 0.004, 0.026, 0.034, 0.01, and 0.01, Wilcoxon Signed Ranks) consecutively. BCVA (LogMAR) was 0.33 ± 0.34 and improved to 0.13 ± 0.11 at 1 year. Mean number of medications dropped from 1.9 ± 1 preoperatively to 0.3 ± 0.49 (p = 0.003) at 1 year. 42% of eyes achieved complete success and 66% qualified success. Complications included choroidal detachment in 2 eyes, and implant extrusion in 1 eye, and 2 eyes underwent trabeculectomy. Conclusion. XEN implant is an effective surgical treatment for POAG, with significant reduction in IOP and glaucoma medications at 1 year follow-up. PMID:28348884

  14. Household hazardous waste collection results, state fiscal years 1996, 1997, 1998

    SciTech Connect

    Rion, D.

    1998-12-01

    Some household products are potentially dangerous to living things and the environment when disposed of improperly. The Illinois Environmental Protection Agency (IEPA) has designed a program to deal with such problem wastes. Utilizing funds from the Solid Waste Management Fund, the Agency sponsored 90 collections during the state fiscal years 1996, 1997, and 1998. The report details the need for household hazardous waste collections in Illinois and summarizes the results of the projects.

  15. One-Year Results for the Kelly Air Force Base Compressed Work Week Survey

    DTIC Science & Technology

    1994-01-01

    home and at work, resulting in social stability. 14. SUBJECT TERMS 15. NUMBER OF PAGES Compressed Work Week Lifestyle .44 Attitude Survey Air Force Base...for 1-year. Few published studies have investigated the impact of CWS on the lifestyle or quality of life of the employee, particularly over extended...grouped into lifestyle subcategories (family, community, health, leisure, social, cultural, sleep, and finances) or job related subcategories

  16. 10-year results of the uncemented Allofit press-fit cup in young patients

    PubMed Central

    Streit, Marcus R; Weiss, Stefan; Andreas, Franziska; Bruckner, Thomas; Walker, Tilman; Kretzer, J Philippe; Ewerbeck, Volker; Merle, Christian

    2014-01-01

    Background and purpose Uncemented acetabular components in primary total hip arthroplasty (THA) are commonly used today, but few studies have evaluated their survival into the second decade in young and active patients. We report on a minimum 10-year follow-up of an uncemented press-fit acetabular component that is still in clinical use. Methods We examined the clinical and radiographic results of our first 121 consecutive cementless THAs using a cementless, grit-blasted, non-porous, titanium alloy press-fit cup (Allofit; Zimmer Inc., Warsaw, IN) without additional screw fixation in 116 patients. Mean age at surgery was 51 (21–60) years. Mean time of follow-up evaluation was 11 (10–12) years. Results At final follow-up, 8 patients had died (8 hips), and 1 patient (1 hip) was lost to follow-up. 3 hips in 3 patients had undergone acetabular revision, 2 for deep infection and 1 for aseptic acetabular loosening. There were no impending revisions at the most recent follow-up. We did not detect periacetabular osteolysis or loosening on plain radiographs in those hips that were evaluated radiographically (n = 90; 83% of the hips available at a minimum of 10 years). Kaplan-Meier survival analysis using revision of the acetabular component for any reason (including isolated inlay revisions) as endpoint estimated the 11-year survival rate at 98% (95% CI: 92–99). Interpretation Uncemented acetabular fixation using the Allofit press-fit cup without additional screws was excellent into early in the second decade in this young and active patient cohort. The rate of complications related to the liner and to osteolysis was low. PMID:24875058

  17. Impaction bone grafting for tibial defects in knee replacement surgery. Results at two years.

    PubMed

    Naim, Soulat; Toms, Andrew D

    2013-04-01

    Bone loss with large defects poses a complex and challenging problem in primary and revision knee arthroplasty. The defects are often irregular and difficult to quantify. One of the techniques available to restore bone in such cases is Knee Impaction Bone Grafting (KIBG); however, the clinical literature to support this technique is weak. Since 2006 we have used impaction bone grafting for contained and uncontained large tibial defects in primary and revision total knee arthroplasty. We have prospectively studied 11 patients with large tibial defects treated at the Exeter Knee Reconstruction Unit with KIBG using a short cemented stem following the Slooff-Ling philosophy. Average age was 66 years (41-86 years). Minimum follow-up was 2 years. The Knee Society Scores improved from 27.4 to 89.2 on average, with Knee Society Function score and WOMAC increasing by 263 and 23.2 points respectively. The mean post-operative flexion was 112 degrees. The average gain in motion over preoperative value was 20 degrees. At two years there were no mechanical failures. None of the patients have required secondary procedures or further revisions. All radiographs showed incorporation and remodelling of the graft. The only complication was a superficial dysaesthesia around the operative scar. Although being time consuming and technically demanding, KIBG for substantial tibial bone loss has shown excellent versatility and good short term results, providing a stable construct with immediate weight bearing post operatively. In view of previous concerns regarding early incorporation and stability of impaction bone grafting in the tibia, we present our early results at 2 years. This technique has become our preferred technique for treating substantial bone loss in tibial defects seen in primary and revision knee arthroplasty surgery.

  18. Results of Medium Seventeen Years' Follow-Up after Laparoscopic Choledochotomy for Ductal Stones.

    PubMed

    Quaresima, Silvia; Balla, Andrea; Guerrieri, Mario; Lezoche, Giovanni; Campagnacci, Roberto; D'Ambrosio, Giancarlo; Lezoche, Emanuele; Paganini, Alessandro M

    2016-01-01

    Introduction. In a previously published article the authors reported the long-term follow-up results in 138 consecutive patients with gallstones and common bile duct (CBD) stones who underwent laparoscopic transverse choledochotomy (TC) with T-tube biliary drainage and laparoscopic cholecystectomy (LC). Aim of this study is to evaluate the results at up to 23 years of follow-up in the same series. Methods. One hundred twenty-one patients are the object of the present study. Patients were evaluated by clinical visit, blood assay, and abdominal ultrasound. Symptomatic patients underwent cholangio-MRI, followed by endoscopic retrograde cholangiopancreatography (ERCP) as required. Results. Out of 121 patients, 61 elderly patients died from unrelated causes. Fourteen patients were lost to follow-up. In the 46 remaining patients, ductal stone recurrence occurred in one case (2,1%) successfully managed by ERCP with endoscopic sphincterotomy. At a mean follow-up of 17.1 years no other patients showed signs of bile stasis and no patient showed any imaging evidence of CBD stricture at the site of choledochotomy. Conclusions. Laparoscopic transverse choledochotomy with routine T-tube biliary drainage during LC has proven to be safe and effective at up to 23 years of follow-up, with no evidence of CBD stricture when the procedure is performed with a correct technique.

  19. Results of Medium Seventeen Years' Follow-Up after Laparoscopic Choledochotomy for Ductal Stones

    PubMed Central

    Quaresima, Silvia; Balla, Andrea; Guerrieri, Mario; Campagnacci, Roberto; D'Ambrosio, Giancarlo; Lezoche, Emanuele; Paganini, Alessandro M.

    2016-01-01

    Introduction. In a previously published article the authors reported the long-term follow-up results in 138 consecutive patients with gallstones and common bile duct (CBD) stones who underwent laparoscopic transverse choledochotomy (TC) with T-tube biliary drainage and laparoscopic cholecystectomy (LC). Aim of this study is to evaluate the results at up to 23 years of follow-up in the same series. Methods. One hundred twenty-one patients are the object of the present study. Patients were evaluated by clinical visit, blood assay, and abdominal ultrasound. Symptomatic patients underwent cholangio-MRI, followed by endoscopic retrograde cholangiopancreatography (ERCP) as required. Results. Out of 121 patients, 61 elderly patients died from unrelated causes. Fourteen patients were lost to follow-up. In the 46 remaining patients, ductal stone recurrence occurred in one case (2,1%) successfully managed by ERCP with endoscopic sphincterotomy. At a mean follow-up of 17.1 years no other patients showed signs of bile stasis and no patient showed any imaging evidence of CBD stricture at the site of choledochotomy. Conclusions. Laparoscopic transverse choledochotomy with routine T-tube biliary drainage during LC has proven to be safe and effective at up to 23 years of follow-up, with no evidence of CBD stricture when the procedure is performed with a correct technique. PMID:26880900

  20. Pipeline for uncoilable or failed aneurysms: 3-year follow-up results.

    PubMed

    Becske, Tibor; Potts, Matthew B; Shapiro, Maksim; Kallmes, David F; Brinjikji, Waleed; Saatci, Isil; McDougall, Cameron G; Szikora, István; Lanzino, Giuseppe; Moran, Christopher J; Woo, Henry H; Lopes, Demetrius K; Berez, Aaron L; Cher, Daniel J; Siddiqui, Adnan H; Levy, Elad I; Albuquerque, Felipe C; Fiorella, David J; Berentei, Zsolt; Marosföi, Miklós; Cekirge, Saruhan H; Nelson, Peter K

    2016-10-14

    OBJECTIVE The long-term effectiveness of endovascular treatment of large and giant wide-neck aneurysms using traditional endovascular techniques has been disappointing, with high recanalization and re-treatment rates. Flow diversion with the Pipeline Embolization Device (PED) has been recently used as a stand-alone therapy for complex aneurysms, showing significant improvement in effectiveness while demonstrating a similar safety profile to stent-supported coil treatment. However, relatively little is known about its long-term safety and effectiveness. Here the authors report on the 3-year safety and effectiveness of flow diversion with the PED in a prospective cohort of patients with large and giant internal carotid artery aneurysms enrolled in the Pipeline for Uncoilable or Failed Aneurysms (PUFS) trial. METHODS The PUFS trial is a prospective study of 107 patients with 109 aneurysms treated with the PED. Primary effectiveness and safety end points were demonstrated based on independently monitored 180-day clinical and angiographic data. Patients were enrolled in a long-term follow-up protocol including 1-, 3-, and 5-year clinical and imaging follow-up. In this paper, the authors report the midstudy (3-year) effectiveness and safety data. RESULTS At 3 years posttreatment, 74 subjects with 76 aneurysms underwent catheter angiography as required per protocol. Overall, complete angiographic aneurysm occlusion was observed in 71 of these 76 aneurysms (93.4% cure rate). Five aneurysms were re-treated, using either coils or additional PEDs, for failure to occlude, and 3 of these 5 were cured by the 3-year follow-up. Angiographic cure with one or two treatments of Pipeline embolization alone was therefore achieved in 92.1%. No recanalization of a previously completely occluded aneurysm was noted on the 3-year angiograms. There were 3 (2.6%) delayed device- or aneurysm-related serious adverse events, none of which led to permanent neurological sequelae. No major or minor

  1. Ten-year results of a double-heat-treated metal-on-metal hip resurfacing.

    PubMed

    Daniel, J; Ziaee, H; Kamali, A; Pradhan, C; Band, T; McMinn, D J W

    2010-01-01

    Second-generation metal-on-metal bearings were introduced as a response to the considerable incidence of wear-induced failures associated with conventional replacements, especially in young patients. We present the results at ten years of a consecutive series of patients treated using a metal-on-metal hip resurfacing. A distinct feature of the bearings used in our series was that they had been subjected to double-heat treatments during the post-casting phase of their manufacture. In the past these bearings had not been subjected to thermal treatments, making this a unique metal-on-metal bearing which had not been used before in clinical practice. We report the outcome of 184 consecutive hips (160 patients) treated using a hybrid-fixed metal-on-metal hip resurfacing during 1996. Patients were invited for a clinicoradiological follow-up at a minimum of ten years. The Oxford hip score and anteroposterior and lateral radiographs were obtained. The mean age at operation was 54 years (21 to 75). A series of 107 consecutive hips (99 patients) who received the same prosthesis, but subjected to a single thermal treatment after being cast, between March 1994 and December 1995, were used as a control group for comparison. In the 1994 to 1995 group seven patients (seven hips) died from unrelated causes and there were four revisions (4%) for osteolysis and aseptic loosening. In the 1996 group nine patients died at a mean of 6.9 years after operation because of unrelated causes. There were 30 revisions (16%) at a mean of 7.3 years (1.2 to 10.9), one for infection at 1.2 years and 29 for osteolysis and aseptic loosening. Furthermore, in the latter group there were radiological signs of failure in 27 (24%) of the 111 surviving hips. The magnitude of the problem of osteolysis and aseptic loosening in the 1996 cohort did not become obvious until five years after the operation. Our results indicate that double-heat treatments of metal-on-metal bearings can lead to an increased

  2. Kineflex (Centurion) Lumbar Disc Prosthesis: Insertion Technique and 2-Year Clinical Results in 100 Patients

    PubMed Central

    Weinberg, Ian R.; Sliwa, Karen; Sweet, Barry MBE; de Villiers, Malan

    2007-01-01

    Background The Kineflex lumbar disc is a mechanical, unconstrained, re-centering disc prosthesis developed in South Africa. The first implantation took place in October 2002. We present a single-center, prospective, longitudinal study of the first 100 patients treated with the Kineflex lumbar disc. Our objective was to evaluate the insertion technique, clinical outcomes, and patient satisfaction at 2 years postimplantation in 100 consecutive patients with 132 (68 single- and 32 2-level) Kineflex lumbar disc replacements. Methods We determined the exact central placement of all disc implants in the coronal and midsagittal planes. We measured clinical outcome with the Oswestry disability index (ODI), our own questionnaire, and the time needed to return to work. All patients received radiological and clinical follow-up assessments for 2 years after the index procedure. Results Forty-three patients were female. The mean age of the patients at operation was 44.9 years (range, 23–63 years). Postoperative hospitalization averaged 2.8 days (range, 2 to 8 days). All patients who were employed before surgery returned to work 31 ± 16.8 days after the operation. Fifty-six percent of operated disc levels had intervertebral disc heights of less than 5 mm. A 2-year clinical outcome was available for 98 of the 100 patients (58 excellent, 30 good, 7 fair, 3 poor). The ODI score improved from 47.8 ± 16.0 preoperatively to 14.2 ± 14.0 (P < .01) at 2 years. At 2 years, 95% of disc implants were radiologically in the ideal position. The insertion technique, with a released prosthetic mechanism for final placement, allowed ideal placement in the sagittal plane in 98% of discs. The radiographic placement accuracy achieved was equal in patients with preoperative intervertebral disc height below and above 5 mm. Conclusions Good short-term clinical results were achieved with the Kineflex disc in a heterogeneous patient group with a high number of patients with advanced disc

  3. Allergen-Specific Immunotherapy in Patients 55 Years and Older: Results and Review of Literature

    PubMed Central

    Baptistella, Eduardo; Maniglia, Sergio; Malucelli, Diego Augusto; Rispoli, Daniel; Pruner de Silva, Thanara; Tsuru, Fernanda Miyoko; Becker, Renata Vecentin; Bernardi, Gustavo; Dranka, Daniela; Ferraz, Bruno

    2013-01-01

    Introduction Over the years the immune system suffers many morphologic and functional alterations, which result in a peak of function in puberty and a gradual decrease in the elderly. Aim Treat patients 55 years or older with allergic rhinitis with immunotherapy and then analyze the response to allergens. Materials and Methods From June 2009 to July 2010, 104 charts of patients 55 years or older with allergic complaints were evaluated. The patients were selected by anamnesis, physical examination, and otorhinolaryngologic exam. The patients had cutaneous test for mites before and after 1 year of sublingual specific immunotherapy. The cutaneous response was classified as negative (absent), light, moderate, or severe. Results Before vaccination, 42 (40.4%) patients were classified as having a severe form of allergy and 62 (59.6%) as having a moderate allergy. After the specific therapy, 40 (38.4%) patients were classified as negative (absent), 37 (35.6%) as light, 19 (18.3%) as moderate, and 8 (7.7%) as severe responses. Conclusion Immunotherapy, a desensitization technique, is indicated in cases which patients cannot avoid the exposure to allergens and in situations where pharmacologic therapy is not ideal. Specific immunotherapy to treat the allergic rhinitis in elderly patients was efficient and had no collateral effects, and in addition to the clinical benefit, improvement in the cutaneous test could also be observed. PMID:25992039

  4. Results and Implications of Seven Years of the University of Arizona Astronomy Club

    NASA Astrophysics Data System (ADS)

    Walker-LaFollette, Amanda; Towner, A. P.; Hardegree-Ullman, K.; Brissenden, G.

    2014-01-01

    Participation in an undergraduate astronomy club or organization, be it social, academic, outreach-, or research-oriented, can be extremely beneficial to astronomy students. In this talk, we present the numerical results of the past seven years of University of Arizona Astronomy Club activities, particularly those relating to published papers, poster presentations, attendance at AAS meetings, and retention within the major. We also discuss less-quantifiable results, such as social, academic, and emotional support for club members. Finally, we highlight the efforts being performed by undergraduates at institutions all around the country, as presented in this Session.

  5. The NUCLEON experiment. Results of the first year of data acquisition

    NASA Astrophysics Data System (ADS)

    Atkin, E.; Bulatov, V.; Dorokhov, V.; Filippov, S.; Gorbunov, N.; Grebenyuk, V.; Karmanov, D.; Kovalev, I.; Kudryashov, I.; Kurganov, A.; Merkin, M.; Panov, A.; Podorozhny, D.; Polkov, D.; Porokhovoy, S.; Shumikhin, V.; Sveshnikova, L.; Tkachenko, A.; Tkachev, L.; Turundaevskiy, A.; Vasiliev, O.; Voronin, A.

    2017-04-01

    The NUCLEON experiment aims to study chemical composition and energy spectra of galactic cosmic rays for nuclei charges Z = 1 - 30 and energies 1011 -1015 eV. The research is conducted with the help of the NUCLEON scientific equipment installed on the Russian satellite ;Resurs-P; No. 2 as an additional payload. This article describes the results of the first year of the space experiment NUCLEON, including methodological features of data acquisition mode setup, evaluation of the equipment's performance and methods it provides, as well as preliminary results of data analysis.

  6. Corneal Aberrations, Contrast Sensitivity, and Light Distortion in Orthokeratology Patients: 1-Year Results

    PubMed Central

    2016-01-01

    Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = −2.19 ± 0.97 D were evaluated at 1 day, 1 month, and 1 year after starting OK treatment. Monocular LD, photopic monocular CSF, and corneal HOA for 6 mm pupil size were measured. Results. LD showed an increase after the first night (p < 0.05) and recovery to baseline after 1 month, remaining stable after 1 year (p > 0.05). Spherical-like, coma-like, and secondary astigmatism HOA RMS increased significantly (p ≤ 0.022) from baseline to 1-month visit, remaining unchanged over the follow-up. Contrast sensitivity for medium frequencies (3.0, 4.24, and 6.00 cpd) was significantly correlated with LD parameters at baseline (r ≤ −0.529, p < 0.001). However, after 1 year of treatment, this correlation was only statistically significant for 12 cpd spatial frequency (r ≤ −0.565, p < 0.001). Spherical-like RMS for 6 mm pupil size correlated with irregularity of the LD (r = −0.420, p < 0.05) at the 1-year visit. Conclusion. LD experienced by OK patients recovers after one month of treatment and remains stable in the long term while optical aberrations remain significantly higher than baseline. PMID:27867660

  7. Corneal Aberrations, Contrast Sensitivity, and Light Distortion in Orthokeratology Patients: 1-Year Results.

    PubMed

    Santolaria-Sanz, Elena; Cerviño, Alejandro; González-Méijome, José M

    2016-01-01

    Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at 1 day, 1 month, and 1 year after starting OK treatment. Monocular LD, photopic monocular CSF, and corneal HOA for 6 mm pupil size were measured. Results. LD showed an increase after the first night (p < 0.05) and recovery to baseline after 1 month, remaining stable after 1 year (p > 0.05). Spherical-like, coma-like, and secondary astigmatism HOA RMS increased significantly (p ≤ 0.022) from baseline to 1-month visit, remaining unchanged over the follow-up. Contrast sensitivity for medium frequencies (3.0, 4.24, and 6.00 cpd) was significantly correlated with LD parameters at baseline (r ≤ -0.529, p < 0.001). However, after 1 year of treatment, this correlation was only statistically significant for 12 cpd spatial frequency (r ≤ -0.565, p < 0.001). Spherical-like RMS for 6 mm pupil size correlated with irregularity of the LD (r = -0.420, p < 0.05) at the 1-year visit. Conclusion. LD experienced by OK patients recovers after one month of treatment and remains stable in the long term while optical aberrations remain significantly higher than baseline.

  8. Two-year outcomes of patients with newly diagnosed atrial fibrillation: results from GARFIELD-AF

    PubMed Central

    Bassand, Jean-Pierre; Accetta, Gabriele; Camm, Alan John; Cools, Frank; Fitzmaurice, David A.; Fox, Keith A.A.; Goldhaber, Samuel Z.; Goto, Shinya; Haas, Sylvia; Hacke, Werner; Kayani, Gloria; Mantovani, Lorenzo G.; Misselwitz, Frank; ten Cate, Hugo; Turpie, Alexander G.G.; Verheugt, Freek W.A.; Kakkar, Ajay K.

    2016-01-01

    Aims The relationship between outcomes and time after diagnosis for patients with non-valvular atrial fibrillation (NVAF) is poorly defined, especially beyond the first year. Methods and results GARFIELD-AF is an ongoing, global observational study of adults with newly diagnosed NVAF. Two-year outcomes of 17 162 patients prospectively enrolled in GARFIELD-AF were analysed in light of baseline characteristics, risk profiles for stroke/systemic embolism (SE), and antithrombotic therapy. The mean (standard deviation) age was 69.8 (11.4) years, 43.8% were women, and the mean CHA2DS2-VASc score was 3.3 (1.6); 60.8% of patients were prescribed anticoagulant therapy with/without antiplatelet (AP) therapy, 27.4% AP monotherapy, and 11.8% no antithrombotic therapy. At 2-year follow-up, all-cause mortality, stroke/SE, and major bleeding had occurred at a rate (95% confidence interval) of 3.83 (3.62; 4.05), 1.25 (1.13; 1.38), and 0.70 (0.62; 0.81) per 100 person-years, respectively. Rates for all three major events were highest during the first 4 months. Congestive heart failure, acute coronary syndromes, sudden/unwitnessed death, malignancy, respiratory failure, and infection/sepsis accounted for 65% of all known causes of death and strokes for <10%. Anticoagulant treatment was associated with a 35% lower risk of death. Conclusion The most frequent of the three major outcome measures was death, whose most common causes are not known to be significantly influenced by anticoagulation. This suggests that a more comprehensive approach to the management of NVAF may be needed to improve outcome. This could include, in addition to anticoagulation, interventions targeting modifiable, cause-specific risk factors for death. Clinical Trial Registration http://www.clinicaltrials.gov. Unique identifier: NCT01090362. PMID:27357359

  9. Biofilm formation and control in a simulated spacecraft water system - Two-year results

    NASA Technical Reports Server (NTRS)

    Schultz, John R.; Taylor, Robert D.; Flanagan, David T.; Carr, Sandra E.; Bruce, Rebekah J.; Svoboda, Judy V.; Huls, M. H.; Sauer, Richard L.; Pierson, Duane L.

    1991-01-01

    The ability of iodine to maintain microbial water quality in a simulated spacecraft water system is being studied. An iodine level of about 2.0 mg/L is maintained by passing ultrapure influent water through an iodinated ion exchange resin. Six liters are withdrawn daily and the chemical and microbial quality of the water is monitored regularly. Stainless steel coupons used to monitor biofilm formation are being analyzed by culture methods, epifluorescence microscopy, and scanning electron microscopy. Results from the first two years of operation show a single episode of high bacterial colony counts in the iodinated system. This growth was apparently controlled by replacing the iodinated ion exchange resin. Scanning electron microscopy indicates that the iodine has limited but not completely eliminated the formation of biofilm during the first two years of operation. Significant microbial contamination has been present continuously in a parallel noniodinated system since the third week of operation.

  10. Rare Perilunate Injury as a Result of Chronic Trauma in 3-Year-Old Girl

    PubMed Central

    Tomaszewski, Ryszard

    2015-01-01

    A 3-year-old girl was reported to have perilunate dislocation. The child had suffered, approximately 18 months before, a repetitive wrist injury by means of frequent pulling and bending of the hand by the father who may have physically abused the child for approximately 2 months. At the age of 3 years and 4 months, we performed the reduction of the perilunate dislocation and the plasty of the dorsal scapholunate ligament using the capsular flap prepared from the extensor retinaculum. The wrist was immobilized for 6 weeks. Two months after surgery, patient started the physiotherapy for 3 months. The patient could flex up the wrist to 40 degrees and extend up to 45 degrees (mobility of the healthy wrist was 60, 50 degrees) during the examination 24 months' post-op. Only the surgical treatment of the perilunate dislocation can lead to obtain the good surgical result. PMID:26788457

  11. Unilateral arm transplant 28 years after amputation: fourteen-month result.

    PubMed

    Jablecki, J; Kaczmarzyk, L; Kaczmarzyk, J; Chelmonski, A

    2011-11-01

    Hand transplantation now represents a therapeutic alternative for amputees. Arm transplantation poses a serious challenge regarding many respects of the reconstructive procedure. To the end of 2010, only seven such procedures had been performed in four patients. The goal of this article was to present the preliminary results of an arm transplant in a 30-year-old male patient at 14 months. The patient sustained an amputation at the elbow-joint level as a 2-year-old child. The procedure was performed in October 2010. His postoperative course was complicated by one rejection episode (BANFF grade II), and a de novo cytomegalovirus infection. At this early stage, the patient is doing well regaining function. He can flex at the elbow joint, move his fingers, and experience protective sensitivity reaching the palm. The patient is satisfied with his transplantation.

  12. Patch-test results in children and adolescents: systematic review of a 15-year period*

    PubMed Central

    Rodrigues, Dulcilea Ferraz; Goulart, Eugênio Marcos Andrade

    2016-01-01

    The number of studies on patch-test results in children and adolescents has gradually increased in recent years, thus stimulating reviews. This paper is a systematic review of a 15-year period devoted to studying the issue. Variations pertaining to the number and age groups of tested children and/or adolescents, the number of subjects with atopy/atopic dermatitis history, the quantity, type and concentrations of the tested substances, the test technique and type of data regarding clinical relevance, must all be considered in evaluating these studies, as they make it harder to formulate conclusions. The most common allergens in children were nickel, thimerosal, cobalt, fragrance, lanolin and neomycin. In adolescents, they were nickel, thimerosal, cobalt, fragrance, potassium dichromate, and Myroxylon pereirae. Knowledge of this matter aids health professionals in planning preventive programs aimed at improving children's quality of life and ensuring that their future prospects are not undermined. PMID:26982781

  13. Prospective clinical study of press-ceramic overlap and full veneer restorations: 7-year results.

    PubMed

    Guess, Petra C; Selz, Christian F; Voulgarakis, Apostolos; Stampf, Susanne; Stappert, Christian F J

    2014-01-01

    The aim of this prospective clinical study was to investigate the long-term performance of all-ceramic veneers with overlap (OV) and full veneer (FV) preparation designs. Twenty-five patients were restored using 42 OV restorations (incisal/palatal butt-joint margin) and 24 FV restorations (palatal rounded shoulder margin). All restorations were leucite-reinforced glass-ceramic anterior veneers. The 7-year Kaplan-Meier survival rate was 100% for FV restorations and 97.6% for OV restorations. The all-ceramic veneers revealed significant deterioration over time according to United States Public Health Service criteria, irrespective of the preparation design. Based on the 7-year results of this study, both preparation designs can be considered reliable treatment options for anterior teeth with extended deficits.

  14. [Breast cancer mass screening in the Province of Liege. Results after 8 years].

    PubMed

    Gordenne, W; Parmentier, J C; Delleuze, J M

    2000-08-01

    Breast cancer mass screening by mobile units started in 1992 in the Province of Liège (Belgium). This project is developed for rural areas and interests all women between 40-69 years old not regularly X-rayed in traditional breast cancer diagnosis centers. Despite lots of efforts population participation is low (25%). Nevertheless, the experiment results are encouraging: in a series of 31,443 women, 213 cancers were diagnosed, corresponding to a rate of 6.9/1000, 75% of which are of good prognosis. After an 8 years experiment, it is hoped that the population concerned becomes more sensitive to this mass screening project and one should expect a better collaboration with the other actors in the field of breast diseases diagnosis.

  15. Long-Term Results after Surgical Treatment of Ebstein's Anomaly: a 30-year Experience

    PubMed Central

    Kim, Min-Seok; Lim, Hong-Gook; Kim, Woong Han; Lee, Jeong Ryul

    2016-01-01

    Background and Objectives The aim of the study is to evaluate the long-term results after a surgical repair of Ebstein's anomaly. Subjects and Methods Forty-eight patients with Ebstein's anomaly who underwent open heart surgery between 1982 and 2013 were included. Median age at operation was 5.6 years (1 day-42.1 years). Forty-five patients (93.7%) demonstrated tricuspid valve (TV) regurgitation of less than moderate degree. When the patients were divided according to Carpentier's classification, types A, B, C, and D were 11, 21, 12, and 4 patients, respectively. Regarding the type of surgical treatment, bi-ventricular repair (n=38), one-and-a half ventricular repair (n=5), and single ventricle palliation (n=5) were performed. Of 38 patients who underwent a bi-ventricular repair, TV repairs were performed by Danielson's technique (n=20), Carpentier's technique (n=11), Cone repair (n=4), and TV annuloplasty (n=1). Two patients underwent TV replacement. Surgical treatment strategies were different according to Carpentier's types (p<0.001) and patient's age (p=0.022). Results There were 2 in-hospital mortalities (4.2%; 1 neonate and 1 infant) and 2 late mortalities during follow-up. Freedom from recurrent TV regurgitation rates at 5, 10, and 15 years were 88.6%, 66.3%, 52.7%, respectively. TV regurgitation recurrence did not differ according to surgical method (p=0.800). Survival rates at 5, 10, and 20 years were 95.8%, 95.8%, and 85.6%, respectively, and freedom from reoperation rates at 5, 10, and 15 years were 85.9%, 68.0%, and 55.8%, respectively. Conclusion Surgical treatment strategies were decided according to Carpentier's type and patient's age. Overall survival and freedom from reoperation rates at 10 years were 95.8% and 68.0%, respectively. Approximately 25% of patients required a second operation for TV during the follow-up. PMID:27721863

  16. First observational tests of eternal inflation: Analysis methods and WMAP 7-year results

    NASA Astrophysics Data System (ADS)

    Feeney, Stephen M.; Johnson, Matthew C.; Mortlock, Daniel J.; Peiris, Hiranya V.

    2011-08-01

    In the picture of eternal inflation, our observable universe resides inside a single bubble nucleated from an inflating false vacuum. Many of the theories giving rise to eternal inflation predict that we have causal access to collisions with other bubble universes, providing an opportunity to confront these theories with observation. We present the results from the first observational search for the effects of bubble collisions, using cosmic microwave background data from the WMAP satellite. Our search targets a generic set of properties associated with a bubble-collision spacetime, which we describe in detail. We use a modular algorithm that is designed to avoid a posteriori selection effects, automatically picking out the most promising signals, performing a search for causal boundaries, and conducting a full Bayesian parameter estimation and model selection analysis. We outline each component of this algorithm, describing its response to simulated CMB skies with and without bubble collisions. Comparing the results for simulated bubble collisions to the results from an analysis of the WMAP 7-year data, we rule out bubble collisions over a range of parameter space. Our model selection results based on WMAP 7-year data do not warrant augmenting ΛCDM with bubble collisions. Data from the Planck satellite can be used to more definitively test the bubble-collision hypothesis.

  17. Preliminary Third Year Results from the Python Microwave Background Anisotropy Experiment

    NASA Astrophysics Data System (ADS)

    Platt, S. R.; Dragovan, M.; Ruhl, J. E.; Kovak, J.

    1995-05-01

    We report preliminary results from the third year of observations from Amundsen-Scott South Pole Station with the Python microwave background anisotropy experiment. The instrument is a five channel bolometer array, with detectors operating at 50 mK, cooled by a hybrid (3) He-Adiabatic demagnetization refrigerator. Single-mode waveguide optics center the passband at 90 GHz, and couple the detector system to the 0.75m off-axis parabolic primary mirror of the telescope. The measured beamwidths are 0.75(deg) . We combine a fast 5 Hz 3-beam chop of a vertical flat plate with slow .025 Hz telescope beamswitches to produce a gradient-free 4-beam pattern on the sky. The chop amplitude is 2.75(deg) . In each of the first two years of observations with this system we scanned the same 22 fields, centered at alpha = 23.32, delta = -49.5. In both years we detected statistically significant fluctuations with an amplitude of Delta T / T ~ 3.3 times 10(-5) for an anisotropy model with a Gaussian autocorrelation function with a coherence angle of theta_c = 1(deg) . Our new results incorporate observations made in December 1994 that intersperse these fields and sample more fully this region of sky. The entire three year data set will be used to make a difference map of the structure of anisotropy at intermediate angular scales across a 6(deg) times 22(deg) region of sky. This work was supported by the National Science Foundation under a cooperative agreement with the Center for Astrophysical Research in Antarctica (CARA), grant number NSF OPP 89-20223, M.D.'s PYI grant NSF AST 90-57089, and the James S. McDonnell Foundation. CARA is a National Science Foundation Science and Technology Center.

  18. A Pharmaceutical Bioethics Consultation Service: Six-Year Descriptive Characteristics and Results of a Feedback Survey.

    PubMed

    Van Campen, Luann E; Allen, Albert J; Watson, Susan B; Therasse, Donald G

    2015-04-03

    Background: Bioethics consultations are conducted in varied settings, including hospitals, universities, and other research institutions, but there is sparse information about bioethics consultations conducted in corporate settings such as pharmaceutical companies. The purpose of this article is to describe a bioethics consultation service at a pharmaceutical company, to report characteristics of consultations completed by the service over a 6-year period, and to share results of a consultation feedback survey. Methods: Data on the descriptive characteristics of bioethics consultations were collected from 2008 to 2013 and analyzed in Excel 2007. Categorical data were analyzed via the pivot table function, and time-based variables were analyzed via formulas. The feedback survey was administered to consultation requesters from 2009 to 2012 and also analyzed in Excel 2007. Results: Over the 6-year period, 189 bioethics consultations were conducted. The number of consultations increased from five per year in 2008 to approximately one per week in 2013. During this time, the format of the consultation service was changed from a committee-only approach to a tiered approach (tailored to the needs of the case). The five most frequent topics were informed consent, early termination of a clinical trial, benefits and risks, human biological samples, and patient rights. The feedback survey results suggest the consultation service is well regarded overall and viewed as approachable, helpful, and responsive. Conclusions: Pharmaceutical bioethics consultation is a unique category of bioethics consultation that primarily focuses on pharmaceutical research and development but also touches on aspects of clinical ethics, business ethics, and organizational ethics. Results indicate there is a demand for a tiered bioethics consultation service within this pharmaceutical company and that advice was valued. This company's experience indicates that a bioethics consultation service raises

  19. A Pharmaceutical Bioethics Consultation Service: Six-Year Descriptive Characteristics and Results of a Feedback Survey

    PubMed Central

    Van Campen, Luann E.; Allen, Albert J.; Watson, Susan B.; Therasse, Donald G.

    2015-01-01

    Background: Bioethics consultations are conducted in varied settings, including hospitals, universities, and other research institutions, but there is sparse information about bioethics consultations conducted in corporate settings such as pharmaceutical companies. The purpose of this article is to describe a bioethics consultation service at a pharmaceutical company, to report characteristics of consultations completed by the service over a 6-year period, and to share results of a consultation feedback survey. Methods: Data on the descriptive characteristics of bioethics consultations were collected from 2008 to 2013 and analyzed in Excel 2007. Categorical data were analyzed via the pivot table function, and time-based variables were analyzed via formulas. The feedback survey was administered to consultation requesters from 2009 to 2012 and also analyzed in Excel 2007. Results: Over the 6-year period, 189 bioethics consultations were conducted. The number of consultations increased from five per year in 2008 to approximately one per week in 2013. During this time, the format of the consultation service was changed from a committee-only approach to a tiered approach (tailored to the needs of the case). The five most frequent topics were informed consent, early termination of a clinical trial, benefits and risks, human biological samples, and patient rights. The feedback survey results suggest the consultation service is well regarded overall and viewed as approachable, helpful, and responsive. Conclusions: Pharmaceutical bioethics consultation is a unique category of bioethics consultation that primarily focuses on pharmaceutical research and development but also touches on aspects of clinical ethics, business ethics, and organizational ethics. Results indicate there is a demand for a tiered bioethics consultation service within this pharmaceutical company and that advice was valued. This company's experience indicates that a bioethics consultation service raises

  20. Geology of the Southern Utopia Planitia Highland-Lowland Boundary Plain: Second Year Results and Third Year Plan

    NASA Technical Reports Server (NTRS)

    Skinner, J. A., Jr.; Tanaka, K. L.; Hare, T. M.

    2009-01-01

    The southern Utopia highland-lowland boundary (HLB) extends >1500 km westward from Hyblaeus Dorsa to the topographic saddle that separates Isidis and Utopia Planitiae. It contains bench-like platforms that contain depressions, pitted cones (some organized into arcuate chains and thumb-print terrain), isolated domes, buried circular depressions, ring fractures, polygonal fractures, and other locally- to regionally-dispersed landforms [1-2]. The objective of this map project is to clarify the geologic evolution of the southern Utopia Planitia HLB by identifying the geologic, structural, and stratigraphic relationships of surface materials in MTMs 10237, 15237, 20237, 10242, 15242, 20242, 10247, 15247, and 20247. The project was originally awarded in April, 2007 and is in its final year of support. Mapping is on-schedule and formal map submission will occur by December, 2009, with finalization anticipated by April, 2010. Herein, we (1) review specifics regarding mapping data and methods, (2) present nomenclature requests that we feel will assist with unit descriptions, (3) describe Year 2 mapping and science accomplishments, and (4) outline Year 3 technical and managerial approaches for finalizing the geologic map.

  1. [Analysis of the results of the SEIMC External Quality Control Program. Year 2011].

    PubMed

    Ruiz de Gopegui Bordes, Enrique; Guna Serrano, M del Remedio; Orta Mira, Nieves; Ovies, María Rosario; Poveda, Marta; Gimeno Cardona, Concepción

    2013-02-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica [SEIMC]) includes controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2011 controls. Overall, the results obtained in 2011 confirm the excellent skill and good technical standards found in previous years. Nevertheless, erroneous results can be obtained in any laboratory and in clinically relevant determinations. The results of this program highlight the need to implement both internal and external controls, such as those offered by the SEIMC program, in order to ensure maximal quality of microbiological tests.

  2. Results for the Fourth Quarter Calendar Year 2015 Tank 50H Salt Solution Sample

    SciTech Connect

    Crawford, C.

    2016-01-11

    In this memorandum, the chemical and radionuclide contaminant results from the Fourth Quarter Calendar Year 2015 (CY15) sample of Tank 50H salt solution are presented in tabulated form. The Fourth Quarter CY15 Tank 50H samples were obtained on October 29, 2015 and received at Savannah River National Laboratory (SRNL) on October 30, 2015. The information from this characterization will be used by Defense Waste Processing Facility (DWPF) & Saltstone Facility Engineering for the transfer of aqueous waste from Tank 50H to the Salt Feed Tank in the Saltstone Production Facility, where the waste will be treated and disposed of in the Saltstone Disposal Facility. This memorandum compares results, where applicable, to Saltstone Waste Acceptance Criteria (WAC) limits and targets. Data pertaining to the regulatory limits for Resource Conservation and Recovery Act (RCRA) metals will be documented at a later time per the Task Technical and Quality Assurance Plan (TTQAP) for the Tank 50H saltstone task. The chemical and radionuclide contaminant results from the characterization of the Fourth Quarter Calendar Year 2015 (CY15) sampling of Tank 50H were requested by SRR personnel and details of the testing are presented in the SRNL Task Technical and Quality Assurance Plan.

  3. The Atmospheric Lifetime Experiment. IV - Results for CF2Cl2 based on three years data

    NASA Technical Reports Server (NTRS)

    Cunnold, D. M.; Alyea, F. N.; Cardelino, C. A.; Prinn, R. G.; Rasmussen, R. A.; Crawford, A. J.; Simmonds, P. G.

    1983-01-01

    Observations of dichlorodifluoromethane obtained several times daily over the period July 1978 to June 1981 at Adrigole, Ireland (52 deg N, 10 deg W), Ragged Point, Barbados (13 deg N, 59 deg W), Point Matatula, American Samoa (14 deg S, 171 deg W), and Cape Grim, Tasmania (41 deg S, 145 deg E), are reported. Observations at Cape Meares, Oregon (45 deg N, 124 deg W), are also given for the period November 1980 to June 1981. On January 1, 1980, the average mixing ratio of dichlorodifluoromethane in the lower troposphere is estimated to have been 285 pptv and to have been increasing at 6.0 percent/year. The atmospheric lifetime of this compound is estimated from this data by adjusting its destruction rate in a two-dimensional model of the atmosphere so as to provide the best fit to the observations. Assuming destruction of CF2Cl2 in the stratosphere only, the lifetime estimate for January 1, 1980, by the inventory technique is 69 + 36 or - 18 years. The trend technique principally provides a lower limit to the lifetime of 81 years. The results suggest a need for further assessment of dichlorodifluoromethane release estimates, particularly those from the USSR and eastern Europe.

  4. Alternative fuel vehicles for the state fleets: Results of the 5-year planning process

    SciTech Connect

    Not Available

    1993-05-01

    This report documents the first attempt by the Department of Energy (DOE) to work with states to prepare five-year Alternative Fuel Vehicle (AFV) acquisition plans to identify alternative fuels and vehicles that they are planning on or would like to acquire. The DOE Regional Support Offices (RSOs) met with representatives from the states in their regions and assisted in the preparation of the plans. These plans will be used in conjunction with previously gathered Federal five-year plans to encourage Original Equipment Manufacturers (OEMs) to expand the variety of AFVs produced, reduce the incremental cost of AFVs, and to encourage fuel suppliers to expand the alternative fuel infrastructure and alternative fuel availability. By identifying the needs and requirements of state fleets, DOE can begin to describe the specific nature of the future state fleets, and establish a defined market for OEMs and fuel suppliers. DOE initiated the development and collection of the state five-year plans before the signing of the Energy Policy Act, to raise the awareness of states that they will be required by law to acquire AFVs. As a result, several states that had no AFV acquisition plan when queried have developed or are in the process of developing plans. The DOE and its RSOs are still working with the states to develop and refine acquisition plans, and this report should be treated as documentation of work in progress.

  5. First Year Results from the Fermi Gamma-Ray Space Telescope

    NASA Technical Reports Server (NTRS)

    Hays, Elizabeth

    2009-01-01

    After one year of survey observations and more than 70 billion triggers, Fermi is revealing an unprecedented view of the high energy gamma-ray sky. The observatory .carries two instruments, the Gamma-ray Burst Monitor (GB, 8 keV - 40 MeV) and the Large Area Telescope (LAT, 20 MeV greater than or equal to 300 GeV), which in combination cover over 7 orders of magnitude in energy for transient phenomena. The LAT provides substantially more sensitivity than previous instruments in this waveband and has opened up the energy window from 10-100 GeV. The first year has produced many important results, from detections of extremely energetic and distant gamma-ray bursts, to monitoring daily variations in emission caused by massive black holes at the cores of galaxies, to identifying a new population of gamma-ray bright pulsars, to measuring the spectrum of diffuse emission from our own. Galaxy and the spectrum of the local cosmic electrons. I'll review highlights from the first year and discuss how the data are answering questions from the past and raising new ones for the future.

  6. Three years of results from a mooring over a Posidonia Oceanica seagrass meadow (Corsica, France)

    NASA Astrophysics Data System (ADS)

    Champenois, Willy; Delille, Bruno; Lepoint, Gilles; Beckers, Jean-Marie; Grégoire, Marilaure; Borges Alberto, V.

    2010-05-01

    We report the first three years of results from a 10m deep mooring over a Posidonia Oceanica seagrass meadow (Corsica, France) where we deployed from August 2006 to November 2009 an array of 3 optodes. The oxygen data are used to compute by mass balance ecosystem metabolic performance rates (gross primary production (GPP), community respiration (CR), net community production (NCP)), allowing a detailed analysis of seasonal and year-to-year variability of GPP, CR and NCP. The comparison of GPP and CR values derived from the O2 mass balance with rates derived from discrete benthic incubations (every 2 months in 2006-2007, every 4 months in 2008-2009) is very satisfactory. An application of such a mooring is to detect changes in the productivity of the Posidonia meadow that can be used as indicators of overall ecosystem "health" or degradation by human activities. Such a mooring can be used as an affordable and simple tool for management and sustainable development of coastal areas in the Mediterranean.

  7. Comparison of wear and clinical performance between amalgam, composite and open sandwich restorations: 2-year results.

    PubMed

    Sachdeo, A; Gray, Gordon B; Sulieman, M A; Jagger, Daryll C

    2004-03-01

    There has been some disquiet over the use of mercury containing restorative materials. The most commonly used alternative is composite resin but this has the potential disadvantage associated with wear and marginal leakage, which in turn, has proven to result in secondary caries and sensitivity. To overcome the shortcomings of a directly placed composite restoration, the glass-ionomer/composite open sandwich technique was introduced followed by the subsequent introduction of compomer systems. The aims of this study were to evaluate the wear and clinical performance of a control group of amalgam restorations compared with that of a group of posterior composite resin restorations fillings and a group of compomer/composite open sandwich restorations placed by a single general dental practitioner. The duration of the study was 2 years. One hundred and thirty three (71.4%) patients were successfully recalled and the wear and clinical performance of each restoration after 6, 12 and 24 months was measured, indirectly. There was no statistically significant difference recorded between the groups at 6 months or 1 year (p > 0.05). However, at the end of the 2-year study, there was a significantly lower rate of wear recorded for the control amalgam restorations compared with other two groups (p = 0.033). There was no statistically significant difference in wear recorded between the two groups of tooth-coloured restorations (p > 0.05). With regards to clinical performance of the restorations, occlusal and proximal contacts in each group of restoration remained satisfactory throughout the study.

  8. Three-year outcomes after acute kidney injury: results of a prospective parallel group cohort study

    PubMed Central

    Horne, Kerry L; Packington, Rebecca; Monaghan, John; Reilly, Timothy

    2017-01-01

    Objectives Using a prospective study design, we aimed to characterise the effect of acute kidney injury (AKI) on long-term changes in renal function in a general hospital population. Participants Hospitalised patients with AKI (exposed) and hospitalised patients without AKI (non-exposed), recruited at 3 months after hospital admission. Design Prospective, matched parallel group cohort study, in which renal function and proteinuria were measured at 3 months, 1 year and 3 years. Setting Single UK centre. Clinical end points Clinical end points at 3 years were comparison of the following variables between exposed and non-exposed groups: renal function, prevalence of proteinuria and albuminuria and chronic kidney disease (CKD) progression/development at each time point. CKD progression was defined as a decrease in the estimated glomerular filtration rate (eGFR) of ≥25% associated with a decline in eGFR stage. Results 300 exposed and non-exposed patients were successfully matched 1:1 for age and baseline renal function; 70% of the exposed group had AKI stage 1. During follow-up, the AKI group had lower eGFR than non-exposed patients at each time point. At 3 years, the mean eGFR was 60.7±21 mL/min/1.73 m2 in the AKI group compared with 68.4±21 mL/min/1.73 m2 in the non-exposed group, p=0.003. CKD development or progression at 3 years occurred in 30 (24.6%) of the AKI group compared with 10 (7.5%) of the non-exposed group, p<0.001. Albuminuria was more common in the AKI group, and increased with AKI severity. Factors independently associated with CKD development/progression after AKI were non-recovery at 90 days, male gender, diabetes and recurrent AKI. Conclusions AKI is associated with deterioration in renal function to 3 years, even in an unselected population with predominantly AKI stage 1. Non-recovery from AKI is an important factor determining long-term outcome. PMID:28360257

  9. Results from Three Years of Ka-Band Propagation Characterization at Svalbard, Norway

    NASA Technical Reports Server (NTRS)

    Nessel, James; Zemba, Michael; Morse, Jacquelynne

    2015-01-01

    Over the next several years, NASA plans to launch several earth science missions which are expected to achieve data throughputs of 5-40 terabits per day transmitted from low earth orbiting spacecraft to ground stations. The current S-band and X-band frequency allocations in use by NASA, however, are incapable of supporting the data rates required to meet this demand. As such, NASA is in the planning stages to upgrade its existing Near Earth Network (NEN) polar ground stations to support Ka-band (25.5-27 GHz) operations. Consequently, it installed and operated a Ka-band radiometer at the Svalbard site. Svalbard was chosen as the appropriate site for two primary reasons: (1) Svalbard will be the first site to be upgraded to Ka-band operations within the NEN Polar Network enhancement plan, and (2) there exists a complete lack of Ka-band propagation data at this site (as opposed to the Fairbanks, AK NEN site, which has 5 years of characterization collected during the Advanced Communications Technology becomes imperative that characterization of propagation effects at these NEN sites is conducted to determine expected system Satellite (ACTS) campaign). processing and provide the Herein, we discuss the data three-year measurement results performance, particularly at low elevation angles ((is) less than 10 deg) from the ongoing Ka-band propagation characterization where spacecraft signal acquisition typically occurs. Since May 2011, NASA Glenn Research Center has installed and operated a Ka-band radiometer at the NEN site located in Svalbard, Norway. The Ka-band radiometer monitors the water vapor line, as well as 4 frequencies around 26.5 GHz at a fixed 10 deg elevation angle. Three-year data collection results indicate good campaign at Svalbard, Norway. Comparison of these results with the ITU models and existing ERA profile data indicates very good agreement when the 2010 rain maps and cloud statistics are used. Finally, the Svalbard data is used to derive the expected

  10. Results from Three Years of Ka-band Propagation Characterization at Svalbard, Norway

    NASA Technical Reports Server (NTRS)

    Nessel, James A.; Zemba, Michael; Morse, Jacquelynne

    2015-01-01

    Over the next several years, NASA plans to launch several earth science missions which are expected to achieve data throughputs of 5-40 terabits per day transmitted from low earth orbiting spacecraft to ground stations. The current S-band and X-band frequency allocations in use by NASA, however, are incapable of supporting the data rates required to meet this demand. As such, NASA is in the planning stages to upgrade its existing Near Earth Network (NEN) polar ground stations to support Ka-band (25.5-27 GHz) operations. Consequently, it installed and operated a Ka-band radiometer at the Svalbard site. Svalbard was chosen as the appropriate site for two primary reasons: (1) Svalbard will be the first site to be upgraded to Ka-band operations within the NEN Polar Network enhancement plan, and (2) there exists a complete lack of Ka-band propagation data at this site (as opposed to the Fairbanks, AK NEN site, which has 5 years of characterization collected during the Advanced Communications Technology becomes imperative that characterization of propagation effects at these NEN sites is conducted to determine expected system Satellite (ACTS) campaign). processing and provide the Herein, we discuss the data three-year measurement results performance, particularly at low elevation angles ((is) less than 10 deg) from the ongoing Ka-band propagation characterization where spacecraft signal acquisition typically occurs. Since May 2011, NASA Glenn Research Center has installed and operated a Ka-band radiometer at the NEN site located in Svalbard, Norway. The Ka-band radiometer monitors the water vapor line, as well as 4 frequencies around 26.5 GHz at a fixed 10 deg elevation angle. Three-year data collection results indicate good campaign at Svalbard, Norway. Comparison of these results with the ITU models and existing ERA profile data indicates very good agreement when the 2010 rain maps and cloud statistics are used. Finally, the Svalbard data is used to derive the expected

  11. Quality-assurance results for routine water analysis in US Geological Survey laboratories, water year 1991

    USGS Publications Warehouse

    Maloney, T.J.; Ludtke, A.S.; Krizman, T.L.

    1994-01-01

    The US. Geological Survey operates a quality- assurance program based on the analyses of reference samples for the National Water Quality Laboratory in Arvada, Colorado, and the Quality of Water Service Unit in Ocala, Florida. Reference samples containing selected inorganic, nutrient, and low ionic-strength constituents are prepared and disguised as routine samples. The program goal is to determine precision and bias for as many analytical methods offered by the participating laboratories as possible. The samples typically are submitted at a rate of approximately 5 percent of the annual environmental sample load for each constituent. The samples are distributed to the laboratories throughout the year. Analytical data for these reference samples reflect the quality of environmental sample data produced by the laboratories because the samples are processed in the same manner for all steps from sample login through data release. The results are stored permanently in the National Water Data Storage and Retrieval System. During water year 1991, 86 analytical procedures were evaluated at the National Water Quality Laboratory and 37 analytical procedures were evaluated at the Quality of Water Service Unit. An overall evaluation of the inorganic (major ion and trace metal) constituent data for water year 1991 indicated analytical imprecision in the National Water Quality Laboratory for 5 of 67 analytical procedures: aluminum (whole-water recoverable, atomic emission spectrometric, direct-current plasma); calcium (atomic emission spectrometric, direct); fluoride (ion-exchange chromatographic); iron (whole-water recoverable, atomic absorption spectrometric, direct); and sulfate (ion-exchange chromatographic). The results for 11 of 67 analytical procedures had positive or negative bias during water year 1991. Analytical imprecision was indicated in the determination of two of the five National Water Quality Laboratory nutrient constituents: orthophosphate as phosphorus and

  12. PRONE ACCELERATED PARTIAL BREAST IRRADIATION AFTER BREAST-CONSERVING SURGERY: FIVE YEAR RESULTS OF 100 PATIENTS

    PubMed Central

    Formenti, Silvia C.; Hsu, Howard; Fenton-Kerimian, Maria; Roses, Daniel; Guth, Amber; Jozsef, Gabor; Goldberg, Judith D.; DeWyngaert, J. Keith

    2013-01-01

    Purpose To report the 5-year results of a prospective trial of three-dimensional conformal external beam radiotherapy (3D-CRT) to deliver accelerated partial breast irradiation in the prone position (P-APBI). Methods Post-menopausal patients with Stage I breast cancer with non palpable <2 cm tumors, negative margins, and negative nodes, positive hormonal receptors, and no extensive intraductal component (EIC) were eligible. The trial was offered only once eligible patients had refused to undergo standard whole-breast radiotherapy. Patients were simulated and treated on a dedicated table for prone set-up. The 3D-CRT delivered was 30 Gy in five 6 Gy/daily fractions over 10 days with port film verification at each treatment. Ipsilateral breast, ipsilateral nodal, contralateral breast, and distant failure (IBF, INF, CBF, DF) were estimated using the cumulative incidence method. Disease-free, overall, and cancer-specific survival (DFS, OS, CSS) were recorded. Results One hundred patients accrued to this IRB- approved prospective trial, one with bilateral breast cancer. One patient withdrew consent after simulation and another elected to interrupt radiotherapy after receiving two treatments. Ninety-eight patients are evaluable for toxicity and, in one case, both breasts were treated with PBI. Median patient age was 68 years (range 53–88 years); in 55% the tumor size was <1 cm. All patients had hormonal receptor positive cancers: 87% underwent adjuvant anti-hormonal therapy. At a median follow-up of 64 months (range, 2–125 months), there was one local recurrence (1% IBF) and one contralateral breast cancer (1% CBF). There were no deaths due to breast cancer by 5 years. Grade 3 late toxicities occurred in 2 patients (1 breast edema, 1 transient breast pain). Cosmesis was rated good/excellent in 89% of patients with at least 36 months follow-up. Conclusions Five-year efficacy and toxicity of 3D-CRT to deliver prone-PBI are comparable to other experiences with similar

  13. Two-year results after convective radiofrequency water vapor thermal therapy of symptomatic benign prostatic hyperplasia

    PubMed Central

    Dixon, Christopher M; Cedano, Edwin Rijo; Pacik, Dalibor; Vit, Vítězslav; Varga, Gabriel; Wagrell, Lennart; Larson, Thayne R; Mynderse, Lance A

    2016-01-01

    Objective The objective of this study was to assess the effectiveness and safety of convective radiofrequency (RF) water vapor thermal therapy in men with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH); a pilot study design with 2-year follow-up evaluations. Patients and methods Men aged ≥45 years with an International Prostate Symptom Score ≥13, a maximum urinary flow rate (Qmax) ≤15 mL/s, and prostate volume 20–120 cc were enrolled in a prospective, open-label pilot study using convective RF water vapor energy with the Rezūm System. Patients were followed up for 2 years after transurethral thermal treatment at 3 international centers in the Dominican Republic, Czech Republic, and Sweden. The transurethral thermal therapy utilizes radiofrequency to generate wet thermal energy in the form of water vapor injected through a rigid endoscope into the lateral lobes and median lobe as needed. Urinary symptom relief, urinary flow, quality of life (QOL) impact, sexual function, and adverse events (AEs) were assessed at 1 week, 1, 3, 6, 12, and 24 months. Results LUTS, flow rate, and QOL showed significant improvements from baseline; prostate volumes were appreciably reduced. Sexual function was maintained and no de novo erectile dysfunction occurred. The responses evident as early as 1 month after treatment remained consistent and durable over the 24 months of study. Early AEs were typically transient and mild to moderate; most were related to endoscopic instrumentation. No procedure related to late AEs were seen. Conclusion The Rezūm System convective RF thermal therapy is a minimally invasive treatment for BPH/LUTS which can be performed in the office or as an outpatient procedure with minimal associated perioperative AEs. It has no discernable effect on sexual function and provides significant improvement of LUTS that remain durable at 2 years. PMID:27921028

  14. Partial Breast Radiation Therapy With Proton Beam: 5-Year Results With Cosmetic Outcomes

    SciTech Connect

    Bush, David A.; Do, Sharon; Lum, Sharon; Garberoglio, Carlos; Mirshahidi, Hamid; Patyal, Baldev; Grove, Roger; Slater, Jerry D.

    2014-11-01

    Purpose: We updated our previous report of a phase 2 trial using proton beam radiation therapy to deliver partial breast irradiation (PBI) in patients with early stage breast cancer. Methods and Materials: Eligible subjects had invasive nonlobular carcinoma with a maximal dimension of 3 cm. Patients underwent partial mastectomy with negative margins; axillary lymph nodes were negative on sampling. Subjects received postoperative proton beam radiation therapy to the surgical bed. The dose delivered was 40 Gy in 10 fractions, once daily over 2 weeks. Multiple fields were treated daily, and skin-sparing techniques were used. Following treatment, patients were evaluated with clinical assessments and annual mammograms to monitor toxicity, tumor recurrence, and cosmesis. Results: One hundred subjects were enrolled and treated. All patients completed the assigned treatment and were available for post-treatment analysis. The median follow-up was 60 months. Patients had a mean age of 63 years; 90% had ductal histology; the average tumor size was 1.3 cm. Actuarial data at 5 years included ipsilateral breast tumor recurrence-free survival of 97% (95% confidence interval: 100%-93%); disease-free survival of 94%; and overall survival of 95%. There were no cases of grade 3 or higher acute skin reactions, and late skin reactions included 7 cases of grade 1 telangiectasia. Patient- and physician-reported cosmesis was good to excellent in 90% of responses, was not changed from baseline measurements, and was well maintained throughout the entire 5-year follow-up period. Conclusions: Proton beam radiation therapy for PBI produced excellent ipsilateral breast recurrence-free survival with minimal toxicity. The treatment proved to be adaptable to all breast sizes and lumpectomy cavity configurations. Cosmetic results appear to be excellent and unchanged from baseline out to 5 years following treatment. Cosmetic results may be improved over those reported with photon

  15. Clinical Results of Lateral Unicompartmental Knee Arthroplasty: Minimum 2-Year Follow-up

    PubMed Central

    Kim, Kyung Tae; Lee, Song; Kim, Jin Woo; Kang, Min Su

    2016-01-01

    Background We investigated the clinical results and early complications after lateral unicompartmental knee arthroplasty (UKA) using the Zimmer unicompartmental high-flex knee (ZUK) prosthesis with a minimum follow-up of 2 years. Methods Twenty-seven patients (30 cases) who underwent lateral UKA with the ZUK prosthesis between January 2011 and February 2014 were selected for this study. The mean age of the patients was 63.3 years at the time of surgery, and the mean followup was 3 years and 2 months (range, 24 to 48 months). A retrospective investigation method was used to evaluate the clinical and radiographic results with use of the Knee Society (KS) clinical rating system and plain radiography. Results The mean KS pain score was improved from 17.9 points (range, 10 to 30 points) preoperatively to 40.5 points (range, 30 to 45 points) at the final follow-up (p < 0.001). The mean KS knee score and function score significantly increased from 63.2 points (range, 48 to 70 points) and 68.6 points (range, 35 to 80 points), respectively, preoperatively to 86.0 points (range, 74 to 95 points) and 92.4 points (range, 60 to 100 points), respectively, at the final follow-up (p < 0.001). The mean range of motion of the knee was recovered from 127.1° (range, 110° to 135°) preoperatively to 131.6° (range, 120° to 135°) at the final follow-up. The mean tibiofemoral angle changed from 6.2° of valgus (range, 0.1° to 11.4° of valgus) preoperatively to 3.4°of valgus (range, 0.2° to 9.5° of valgus) at the final follow-up. The overall results classified based on the KS knee score were "excellent" in 21 cases and "good" in 8 cases. Revision total knee arthroplasty was required in one case because of consistent pain on the medial side of the knee after surgery. Conclusions The early clinical results of lateral UKA using the ZUK prosthesis were satisfactory for improvement of pain, knee score, function score, and recovery of knee motion. Therefore, the lateral UKA could be a

  16. Results from Two Years of Ka-Band Propagation Characterization at Svalbard, Norway

    NASA Technical Reports Server (NTRS)

    Nessel, James A.; Morse, Jacquelynne Rose; Zemba, Michael

    2014-01-01

    Over the several years, NASA plans to launch several earth science missions which are expected to achieve data throughputs of 5-40 terabits per day transmitted from low earth orbiting spacecraft to ground stations. The current S-band and X-band frequency allocations in use by NASA, however, are incapable of supporting the data rates required to meet this demand. As such, NASA is in the planning stages to upgrade its existing Near Earth Network (NEN) Polar ground stations to support Ka-band (25.5-27 GHz) operations. Consequently, it becomes imperative that characterization of propagation effects at these NEN sites is conducted to determine expected system performance, particularly at low elevation angles ((is) less than 10 deg) where spacecraft signal acquisition typically occurs. Since May 2011, NASA Glenn Research Center has installed and operated a Ka-band radiometer at the NEN site located in Svalbard, Norway. The Ka-band radiometer monitors the water vapor line, as well as 6 frequencies around 26.5 GHz at multiple elevation angles: 45 deg, 20 deg, and 10 deg. Two year data collection results indicate comparable performance to previously characterized northern latitude sites in the United States, i.e., Fairbanks, Alaska. It is observed that cloud cover at the Svalbard site remains the dominant loss mechanism for Ka-band links, resulting in a margin requirement of 4.1 dB to maintain link availability of 99% at 10 deg elevation.

  17. The effects of Crew Resource Management (CRM) training in airline maintenance: Results following three year's experience

    NASA Technical Reports Server (NTRS)

    Taylor, J. C.; Robertson, M. M.

    1995-01-01

    An airline maintenance department undertook a CRM training program to change its safety and operating culture. In 2 1/2 years this airline trained 2200 management staff and salaried professionals. Participants completed attitude surveys immediately before and after the training, as well as two months, six months, and one year afterward. On-site interviews were conducted to test and confirm the survey results. Comparing managers' attitudes immediately after their training with their pretraining attitudes showed significant improvement for three attitudes. A fourth attitude, assertiveness, improved significantly above the pretraining levels two months after training. The expected effect of the training on all four attitude scales did not change significantly thereafter. Participants' self-reported behaviors and interview comments confirmed their shift from passive to more active behaviors over time. Safety, efficiency, and dependability performance were measured before the onset of the training and for some 30 months afterward. Associations with subsequent performance were strongest with positive attitudes about sharing command (participation), assertiveness, and stress management when those attitudes were measured 2 and 12 months after the training. The two month follow-up survey results were especially strong and indicate that active behaviors learned from the CRM training consolidate and strengthen in the months immediately following training.

  18. Osteochondral Defects of the Knee treated with Mosaicplasty. Results at Eight Years of Follow-Up

    PubMed Central

    Zicaro, Juan Pablo; Romoli, Agustin Molina; Revah, Mariano Agustin; Dere, Juan Jose; Yacuzzi, Carlos; Costa-Paz, Matias

    2017-01-01

    Objectives: There are several surgical options described for osteochondral defects of the knee depending on the size, location and condition of subchondral bone. The main indication for a mosaicplasty procedure is a less than 4 cm2 femoral condyle lesion. The purpose of this study was to analyze a series of patients treated with mosaicplasty with average eight years of follow-up. Methods: We retrospectively evaluated sixty-two patients with osteochondral defects of the knee who underwent a mosaicplasty between 2001 and 2014 with a minimum follow-up of 2 years. Patients were evaluated using the Lysholm score, International Knee Documentation Committee Score (IKDC) and Kellgren-Lawrence radiographic scale. Results: The mean Lysholm score was 80.1 and IKDC was 66.7. Forty-two patients had isolated mosaicplasty and 20 patients presented an associated surgical procedure (osteotomy, ACL reconstruction, meniscectomy). There were no significant differences between the Lysholm and IKDC scores in these two groups. Conclusion: We consider that mosaicplasty is a satisfactory procedure with good functional results in patients with focal articular cartilage lesions of the knee.

  19. Results from the first year of the HAWC Gamma Ray Observatory

    NASA Astrophysics Data System (ADS)

    Goodman, Jordan

    2016-07-01

    The High Altitude Water Cherenkov (HAWC) Gamma-ray Observatory in the high mountains of Mexico was completed in March of 2015 and is now giving us a new view of the TeV sky. HAWC is 15 times more sensitive than the previous generation of wide-field EAS gamma-ray instruments and is able to detect the Crab nebula at >6 σ with each daily transit. In our first year of operation, HAWC has a 5σ detection sensitivity for a source of ~50mCrab. Unlike Imaging Atmospheric Cherenkov Telescopes (IACTs), HAWC operates 24hrs/day with over a 95% on-time and observes the entire overhead sky (~2sr). HAWC's peak energy sensitivity is 2-10 TeV which is ~10x higher than IACTs such as VERITAS and HESS, which makes their observations quite complementary. This talk will present results from the first year of HAWC data including our study of the galactic plane including new sources not yet detected by IACTs as well as spectra and morphology of bright sources. In addition, results of our monitoring of transient AGN will be presented.

  20. Control of soil-transmitted helminthiasis in Myanmar: results of 7 years of deworming.

    PubMed

    Tun, Aung; Myat, Su Mon; Gabrielli, Albis Francesco; Montresor, Antonio

    2013-08-01

    After a baseline survey in 2003 which showed an overall parasitological prevalence of soil-transmitted helminths of 69.7% in school children (prevalence of ascariasis 48.5%, prevalence of trichuriasis 57.5% and prevalence of hookworm infection 6.5), a national deworming programme was established. After 7 years of implementation, it had resulted in a significant reduction of STH prevalence (prevalence of any STH 21%, prevalence of ascariasis 5.8%, prevalence of trichuriasis 18.6% and prevalence of hookworm infection 0.3%) as well as a reduction of the infections of moderate-heavy intensity from 18.5% at baseline to less than 7%. The results are encouraging and a reduction of the frequency of deworming can be envisaged in two of four ecological areas of Myanmar.

  1. Historical data retrieval study - Results for the first five years of KSC STS payload processing

    NASA Technical Reports Server (NTRS)

    Ragusa, J. M.

    1986-01-01

    This paper identifies general and specific quantitative and qualitative results from a study of actual operational experiences while processing 185 science, applications, and commercial payloads for the first five years of STS operations at NASA's Kennedy Space Center (KSC). All the non-DOD payloads from STS-2 through STS-33 were part of the study. The emphasis was placed on various program planning and events that affected KSC processing, payload experiences and improvements, payload hardware condition after arrival, services to customers, and the impact of STS operations and delays. From these initial considerations, operational drivers were identified, data for selected processing measurements collected and analyzed, processing criteria and options determined, and STS payload results and conclusions reached. The study showed a significant reduction in time and effort needed by STS customers and KSC to process a wide variety of payload configurations, although even the simplest payloads required more processing resources and time than were initially assumed.

  2. Environmental radiation monitoring in the Chernobyl exclusion zone--history and results 25 years after.

    PubMed

    Bondarkov, Mikhail D; Oskolkov, Boris Ya; Gaschak, Sergey P; Kireev, Sergey I; Maksimenko, Andrey M; Proskura, Nikolai I; Jannik, G Timothy; Farfán, Eduardo B

    2011-10-01

    This paper describes results of the radiation environmental monitoring performed in the Chernobyl Exclusion Zone (ChEZ) during the period following the 1986 Chernobyl Nuclear Power Plant accident. This article presents a brief overview of five comprehensive reports generated under Contract No. DE-AC09-96SR18500 (Washington Savannah River Company LLC, Subcontract No. AC55559N, SOW No. ON8778) and summarizes characteristics of the ChEZ and its post-accident status. The history of development of the radiation monitoring research in the ChEZ is described also. This paper addresses the characteristics of radiation monitoring in the ChEZ, its major goals and objectives, and changes in these goals and objectives in the course of time, depending on the tasks associated with the phase of mitigation of the ChNPP accident consequences. The results of the radiation monitoring in the ChEZ during the last 25 years are also provided.

  3. A 10-year review of outpatient skin biopsy results and skin cancer subtypes.

    PubMed

    DeMarco, Sebastian S; Vos, Paul; Green, Harris; Defazio, Jennifer; Davis, Natalie; Fiz, Lindsey; Phillips, Charles

    2016-01-15

    The results of skin biopsies over a 10 year period were reviewed from the outpatient dermatology clinic at the Brody School of Medicine in Greenville, North Carolina. This research was conducted because there are very few studies that characterize this information over a long-term horizon. The biopsy rate per patient encounter, the clinical reason for the biopsy, the biopsy outcomes, the distribution of cutaneous malignancies per encounter, and the distribution of the subtypes of basal cell carcinoma, squamous cell carcinoma, and melanoma were analyzed. Biopsy logs from January 1, 2001 to December 31, 2010 were reviewed. Our investigation found that 20% of patient encounters resulted in a biopsy. Of these biopsies, 87.9% were performed to rule out malignancy and 12.1% were completed on patients suspected of having inflammatory skin conditions. The basal cell carcinomas diagnosed in Greenville, NC have more aggressive histologic subtypes compared to other studies, whereas the squamous cell carcinomas and melanomas were less aggressive.

  4. ENVIRONMENTAL RADIATION MONITORING IN THE CHERNOBYL EXCLUSION ZONE - HISTORY AND RESULTS 25 YEARS AFTER

    SciTech Connect

    Farfan, E.; Jannik, T.

    2011-10-01

    This article describes results of the radiation environmental monitoring performed in the Chernobyl Exclusion Zone (ChEZ) during the period following the 1986 Chernobyl Nuclear Power Plant accident. This article presents a brief overview of five comprehensive reports generated under Contract No. DE-AC09-96SR18500 (Washington Savannah River Company LLC, Subcontract No. AC55559N, SOW No. ON8778) and summarizes characteristics of the ChEZ and its post-accident status and the history of development of the radiation monitoring research in the ChEZ is described. This article addresses characteristics of the radiation monitoring in the ChEZ, its major goals and objectives, and changes of these goals and objectives in the course of time, depending on the tasks associated with the phase of mitigation of the ChNPP accident consequences. The results of the radiation monitoring in the ChEZ during the last 25 years are also provided.

  5. First Year Mission Results of Passive Measurement Experiment of Dust Particles on ISS (MPAC)

    NASA Astrophysics Data System (ADS)

    Kitazawa, Y.; Neish, M.; Inoue, T.; Imagawa, K.; Fujiwara, A.

    MPAC (Micro-Particles Capturer) performs dust particles capture experiments on the International Space Station (ISS) Russian Service Module (SM), which consists of low density collector (silica-aerogel and polyimide foam) materials and a metal plate (polished 6061-T6 aluminum plate). Three identical units of MPAC were launched by Progress M-45 Cargo Vessel from Baikonur Cosmodrome on August. Those units were deployed side-by-side on a handrail outside the SM. The front surface of each MPAC nominally directs to ram-direction and the back face directs to wake-direction of the ISS. One unit is retrieved to the Earth every year by Soyuz spacecraft. Therefore, exposure duration of individual units is one, two and three years. We should be able to clarify changes in the number of captured space dust particles. The results obtained will contribute greatly to future development of spacecraft. The first unit was retrieved after 315 days'exposure. Ram and wake MPAC surfaces (including the frame structure) have been examined and more than 30 candidates of dust impacts were located, of which at least 11 were confirmed to be impacts. Typical and the largest impact track in an silica-aerogel has curved walls, giving it a slightly bulbous appearance, and it has the entrance diameter about 2mm with a track length of 5mm, though the end of track is unclear. Based on results of Kitazawa et al. (1999), the track was induced by impact of a dust particle which has diameter range 200 - 250 um, impact velocity range 5 - 10 km/s, and incident angle 45°degree. This study provides description of the inspection and chemical analysis results of MPAC, and discuss based on comparison between the results and hypervelocity impact experiments. Additionally, the paper also discuss culation plan of MPAC materials which include future retrieval MPAC units.

  6. Ten- to 15-year results of the Oxford Phase III mobile unicompartmental knee arthroplasty

    PubMed Central

    Lisowski, L. A.; Meijer, L. I.; van den Bekerom, M. P. J.; Pilot, P.; Lisowski, A. E.

    2016-01-01

    Aims The interest in unicompartmental knee arthroplasty (UKA) for medial osteoarthritis has increased rapidly but the long-term follow-up of the Oxford UKAs has yet to be analysed in non-designer centres. We have examined our ten- to 15-year clinical and radiological follow-up data for the Oxford Phase III UKAs. Patients and Methods Between January 1999 and January 2005 a total of 138 consecutive Oxford Phase III arthroplasties were performed by a single surgeon in 129 patients for medial compartment osteoarthritis (71 right and 67 left knees, mean age 72.0 years (47 to 91), mean body mass index 28.2 (20.7 to 52.2)). Both clinical data and radiographs were prospectively recorded and obtained at intervals. Of the 129 patients, 32 patients (32 knees) died, ten patients (12 knees) were not able to take part in the final clinical and radiological assessment due to physical and mental conditions, but via telephone interview it was confirmed that none of these ten patients (12 knees) had a revision of the knee arthroplasty. One patient (two knees) was lost to follow-up. Results The mean follow-up was 11.7 years (10 to 15). A total of 11 knees (8%) were revised. The survival at 15 years with revision for any reason as the endpoint was 90.6% (95% confidence interval (CI) 85.2 to 96.0) and revision related to the prosthesis was 99.3% (95% CI 97.9 to 100). The mean total Knee Society Score was 47 (0 to 80) pre-operatively and 81 (30 to 100) at latest follow-up. The mean Oxford Knee Score was 19 (12 to 40) pre-operatively and 42 (28 to 55) at final follow-up. Radiolucency beneath the tibial component occurred in 22 of 81 prostheses (27.2%) without evidence of loosening. Conclusion This study supports the use of UKA in medial compartment osteoarthritis with excellent long-term functional and radiological outcomes with an excellent 15-year survival rate. Cite this article: Bone Joint J 2016;98-B(10 Suppl B):41–7. PMID:27694515

  7. Ten-year results of quality assurance in radiotherapy chart round

    PubMed Central

    2013-01-01

    Background The Royal Australian and New Zealand College of Radiologists (RANZCR) initiated a unique instrument to audit the quality of patient notes and radiotherapy prescriptions. We present our experience collected over ten years from the use of the RANZCR audit instrument. Methods In this study, the results of data collected prospectively from January 1999 to June 2009 through the audit instrument were assessed. Radiotherapy chart rounds were held weekly in the uro-oncology tumour stream and real time feedback was provided. Electronic medical records were retrospectively assessed in September 2009 to see if any omissions were subsequently corrected. Results In total 2597 patients were audited. One hundred and thirty seven (5%) patients had one hundred and ninety nine omissions in documentation or radiotherapy prescription. In 79% of chart rounds no omissions were found at all, in 12% of chart rounds one omission was found and in 9% of chart rounds two or more omissions were found. Out of 199 omissions, 95% were of record keeping and 2% were omissions in the treatment prescription. Of omissions, 152 (76%) were unfiled investigation results of which 77 (51%) were subsequently corrected. Conclusions Real-time audit with feedback is an effective tool in assessing the standards of radiotherapy documentation in our department, and also probably contributed to the high level of attentiveness. A large proportion of omissions were investigation results, which highlights the need for an improved system of retrieval of investigation results in the radiation oncology department. PMID:23617328

  8. Gamma Knife Radiosurgery for Patients With Nonfunctioning Pituitary Adenomas: Results From a 15-Year Experience

    SciTech Connect

    Pollock, Bruce E. Cochran, Joseph; Natt, Neena; Brown, Paul D.; Erickson, Dana; Link, Michael J.; Garces, Yolanda I.; Foote, Robert L.; Stafford, Scott L.; Schomberg, Paula J.

    2008-04-01

    Purpose: To evaluate the efficacy and complications of stereotactic radiosurgery for patients with nonfunctioning pituitary adenomas (NFA). Methods and Materials: This was a retrospective review of 62 patients with NFA undergoing radiosurgery between 1992 and 2004, of whom 59 (95%) underwent prior tumor resection. The median treatment volume was 4.0 cm{sup 3} (range, 0.8-12.9). The median treatment dose to the tumor margin was 16 Gy (range, 11-20). The median maximum point dose to the optic apparatus was 9.5 Gy (range, 5.0-12.6). The median follow-up period after radiosurgery was 64 months (range, 23-161). Results: Tumor size decreased for 37 patients (60%) and remained unchanged for 23 patients (37%). Two patients (3%) had tumor growth outside the prescribed treatment volume and required additional treatment (fractionated radiation therapy, n = 1; repeat radiosurgery, n 1). Tumor growth control was 95% at 3 and 7 years after radiosurgery. Eleven (27%) of 41 patients with normal (n = 30) or partial (n = 11) anterior pituitary function before radiosurgery developed new deficits at a median of 24 months after radiosurgery. The risk of developing new anterior pituitary deficits at 5 years was 32%. The 5-year risk of developing new anterior pituitary deficits was 18% for patients with a tumor volume of {<=}4.0 cm{sup 3} compared with 58% for patients with a tumor volume >4.0 cm{sup 3} (risk ratio 4.5; 95% confidence interval = 1.3-14.9, p = 0.02). No patient had a decline in visual function. Conclusions: Stereotactic radiosurgery is effective in the management of patients with residual or recurrent NFA, although longer follow-up is needed to evaluate long-term outcomes. The primary complication is hypopituitarism, and the risk of developing new anterior pituitary deficits correlates with the size of the irradiated tumor.

  9. Dental caries development among African-American children: results from a 4-year longitudinal study

    PubMed Central

    Lim, Sungwoo; Tellez, Marisol; Ismail, Amid I.

    2015-01-01

    Objective To examine dental caries development and caries risk factors among preschool African-American children from low-income families in Detroit, Michigan over a four- year window. Methods Data came from a representative sample of 1,021 children (zero to five years) and their caregivers in Detroit. The baseline participants in 2002–03 (W1) were reexamined in 2004–05 (W2) and 2007 (W3). Caries was measured using the International Caries Detection and Assessment System. Bivariate and multivariate analyses for repeated data were conducted to explore associations between caries increment outcomes and demographics, access to dental care, oral health-related behaviors, and social and physical environments. Results The mean number of new NCCL (non-cavitated caries lesions) was 2.8 between W1 and W2 and 2.6 between W2 and W3, while the mean number of new CCL (cavitated caries lesions) was 2.0 and 2.0, respectively, during the same time periods. In younger children (< three years old in W1) higher number of new NCCL than new CCL were observed in both W1–W2 and W2–W3. The risk of new NCCL was associated with child’s soda intake and caregiver’s age. For the risk of new CCL, significant risk factors included baseline NCCL, baseline CCL, as well as child’s age. Baseline caries and child’s soda intake were also associated with the risk of developing new decayed, missing, and filled tooth surfaces. Conclusions Higher number of new NCCL relative to CCL was developed among low-income Africa-American children during early childhood. New caries development was associated with baseline caries and child’s soda intake. PMID:25441657

  10. New Community Education Program on Oceans and Global Climate Change: Results from Our Pilot Year

    NASA Astrophysics Data System (ADS)

    Bruno, B. C.; Wiener, C.

    2010-12-01

    evaluation results from the first year and discuss how our program has been informed by this feedback.

  11. Nine-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Final Maps and Results

    NASA Technical Reports Server (NTRS)

    Bennett, C. L.; Larson, D.; Weiland, J. L.; Jaorsik, N.; Hinshaw, G.; Odegard, N.; Smith, K. M.; Hill, R. S.; Gold, B.; Halpern, M; Komatsu, E.; Nolta, M. R.; Page, L.; Spergel, D. N.; Wollack, E.; Dunkley, J.; Kogut, A.; Limon,, M.; Meyer, S. S.; Tucker, G. S.; Wright, E. L.

    2013-01-01

    We present the final nine-year maps and basic results from the Wilkinson Microwave Anisotropy Probe (WMAP) mission. The full nine-year analysis of the time-ordered data provides updated characterizations and calibrations of the experiment. We also provide new nine-year full sky temperature maps that were processed to reduce the asymmetry of the effective beams. Temperature and polarization sky maps are examined to separate cosmic microwave background (CMB) anisotropy from foreground emission, and both types of signals are analyzed in detail.We provide new point source catalogs as well as new diffuse and point source foreground masks. An updated template-removal process is used for cosmological analysis; new foreground fits are performed, and new foreground reduced are presented.We nowimplement an optimal C(exp -1)1 weighting to compute the temperature angular power spectrum. The WMAP mission has resulted in a highly constrained Lambda-CDM cosmological model with precise and accurate parameters in agreement with a host of other cosmological measurements. When WMAP data are combined with finer scale CMB, baryon acoustic oscillation, and Hubble constant measurements, we find that big bang nucleosynthesis is well supported and there is no compelling evidence for a non-standard number of neutrino species (N(sub eff) = 3.84 +/- 0.40). The model fit also implies that the age of the universe is (sub 0) = 13.772 +/- 0.059 Gyr, and the fit Hubble constant is H(sub 0) = 69.32 +/- 0.80 km/s/ Mpc. Inflation is also supported: the fluctuations are adiabatic, with Gaussian random phases; the detection of a deviation of the scalar spectral index from unity, reported earlier by the WMAP team, now has high statistical significance (n(sub s) = 0.9608+/-0.0080); and the universe is close to flat/Euclidean (Omega = -0.0027+0.0039/-0.0038). Overall, the WMAP mission has resulted in a reduction of the cosmological parameter volume by a factor of 68,000 for the standard six

  12. Nine-year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Final Maps and Results

    NASA Astrophysics Data System (ADS)

    Bennett, C. L.; Larson, D.; Weiland, J. L.; Jarosik, N.; Hinshaw, G.; Odegard, N.; Smith, K. M.; Hill, R. S.; Gold, B.; Halpern, M.; Komatsu, E.; Nolta, M. R.; Page, L.; Spergel, D. N.; Wollack, E.; Dunkley, J.; Kogut, A.; Limon, M.; Meyer, S. S.; Tucker, G. S.; Wright, E. L.

    2013-10-01

    We present the final nine-year maps and basic results from the Wilkinson Microwave Anisotropy Probe (WMAP) mission. The full nine-year analysis of the time-ordered data provides updated characterizations and calibrations of the experiment. We also provide new nine-year full sky temperature maps that were processed to reduce the asymmetry of the effective beams. Temperature and polarization sky maps are examined to separate cosmic microwave background (CMB) anisotropy from foreground emission, and both types of signals are analyzed in detail. We provide new point source catalogs as well as new diffuse and point source foreground masks. An updated template-removal process is used for cosmological analysis; new foreground fits are performed, and new foreground-reduced CMB maps are presented. We now implement an optimal C -1 weighting to compute the temperature angular power spectrum. The WMAP mission has resulted in a highly constrained ΛCDM cosmological model with precise and accurate parameters in agreement with a host of other cosmological measurements. When WMAP data are combined with finer scale CMB, baryon acoustic oscillation, and Hubble constant measurements, we find that big bang nucleosynthesis is well supported and there is no compelling evidence for a non-standard number of neutrino species (N eff = 3.84 ± 0.40). The model fit also implies that the age of the universe is t 0 = 13.772 ± 0.059 Gyr, and the fit Hubble constant is H 0 = 69.32 ± 0.80 km s-1 Mpc-1. Inflation is also supported: the fluctuations are adiabatic, with Gaussian random phases; the detection of a deviation of the scalar spectral index from unity, reported earlier by the WMAP team, now has high statistical significance (ns = 0.9608 ± 0.0080); and the universe is close to flat/Euclidean (\\Omega _k = -0.0027^{+ 0.0039}_{-0.0038}). Overall, the WMAP mission has resulted in a reduction of the cosmological parameter volume by a factor of 68,000 for the standard six-parameter ΛCDM model

  13. Human factors in aircraft incidents - Results of a 7-year study (Andre Allard Memorial Lecture)

    NASA Technical Reports Server (NTRS)

    Billings, C. E.; Reynard, W. D.

    1984-01-01

    It is pointed out that nearly all fatal aircraft accidents are preventable, and that most such accidents are due to human error. The present discussion is concerned with the results of a seven-year study of the data collected by the NASA Aviation Safety Reporting System (ASRS). The Aviation Safety Reporting System was designed to stimulate as large a flow as possible of information regarding errors and operational problems in the conduct of air operations. It was implemented in April, 1976. In the following 7.5 years, 35,000 reports have been received from pilots, controllers, and the armed forces. Human errors are found in more than 80 percent of these reports. Attention is given to the types of events reported, possible causal factors in incidents, the relationship of incidents and accidents, and sources of error in the data. ASRS reports include sufficient detail to permit authorities to institute changes in the national aviation system designed to minimize the likelihood of human error, and to insulate the system against the effects of errors.

  14. Trends and predictors of asthma costs: results from a 10-year longitudinal study.

    PubMed

    Tan, Ngiap Chuan; Nguyen, Hai V; Lye, Weng Kit; Sankari, Usha; Nadkarni, Nivedita V

    2016-03-01

    Research on asthma costs often focuses on estimating average asthma costs. Trends in asthma costs and patterns of medication use, especially for those who have been followed up and under treatment, have received much less attention. This study's objective was to document asthma costs over time for asthma patients who are enrolled in an asthma care programme in Singapore and to identify its predictors, using a 10-year longitudinal dataset.The study population comprised different cohorts of 939 asthma patients entering the programme at different times during 2004-2013. Average asthma costs were estimated and the trends over time examined graphically, within and across patient cohorts. Regression analyses were conducted to examine cost predictors, with a focus on the relationship between risk factors at programme enrolment and subsequent asthma costs.The results indicate that 10-year average annual asthma cost was GBP 341 per patient. The main drivers of costs were asthma medications and consultation fees. Use of combined inhaled corticosteroid/long-acting β-agonist medications increased over time, but this was accompanied by declines in controller drug use, doctor visits and total asthma drug costs. Obesity, smoking and asthma severity were the main predictors of subsequent asthma costs, especially for females.

  15. Twenty five year mortality and air pollution: results from the French PAARC survey

    PubMed Central

    Filleul, L; Rondeau, V; Vandentorren, S; Le Moual, N; Cantagrel, A; Annesi-Maesano, I; Charpin, D; Declercq, C; Neukirch, F; Paris, C; Vervloet, D; Brochard, P; Tessier, J; Kauffmann, F; Baldi, I

    2005-01-01

    Aims and Methods: Long term effects of air pollution on mortality were studied in 14 284 adults who resided in 24 areas from seven French cities when enrolled in the PAARC survey (air pollution and chronic respiratory diseases) in 1974. Daily measurements of sulphur dioxide, total suspended particles, black smoke, nitrogen dioxide, and nitric oxide were made in 24 areas for three years (1974–76). Cox proportional hazards models controlling for individual confounders (smoking, educational level, body mass index, occupational exposure) were applied, and frailty models used to take into account spatial correlation. Indicators of air pollution were the mean concentration. Results: Models were run before and after exclusion of six area monitors influenced by local traffic (NO/NO2 >3 in ppb). After exclusion of these areas, analyses showed that adjusted risk ratios (95% CI) for TSP, BS, NO2, and NO for non-accidental mortality were 1.05 (1.02 to 1.08), 1.07 (1.03 to 1.10), 1.14 (1.03 to 1.25), and 1.11 (1.05 to 1.17) for 10 µg/m3 respectively. Consistent patterns for lung cancer and cardiopulmonary causes were observed. Conclusions: Urban air pollution assessed in the 1970s was associated with increased mortality over 25 years in France. PMID:15961621

  16. OzDES multifibre spectroscopy for the Dark Energy Survey: first-year operation and results

    NASA Astrophysics Data System (ADS)

    Yuan, Fang; Lidman, C.; Davis, T. M.; Childress, M.; Abdalla, F. B.; Banerji, M.; Buckley-Geer, E.; Carnero Rosell, A.; Carollo, D.; Castander, F. J.; D'Andrea, C. B.; Diehl, H. T.; Cunha, C. E.; Foley, R. J.; Frieman, J.; Glazebrook, K.; Gschwend, J.; Hinton, S.; Jouvel, S.; Kessler, R.; Kim, A. G.; King, A. L.; Kuehn, K.; Kuhlmann, S.; Lewis, G. F.; Lin, H.; Martini, P.; McMahon, R. G.; Mould, J.; Nichol, R. C.; Norris, R. P.; O'Neill, C. R.; Ostrovski, F.; Papadopoulos, A.; Parkinson, D.; Reed, S.; Romer, A. K.; Rooney, P. J.; Rozo, E.; Rykoff, E. S.; Sako, M.; Scalzo, R.; Schmidt, B. P.; Scolnic, D.; Seymour, N.; Sharp, R.; Sobreira, F.; Sullivan, M.; Thomas, R. C.; Tucker, D.; Uddin, S. A.; Wechsler, R. H.; Wester, W.; Wilcox, H.; Zhang, B.; Abbott, T.; Allam, S.; Bauer, A. H.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Burke, D. L.; Carrasco Kind, M.; Covarrubias, R.; Crocce, M.; da Costa, L. N.; DePoy, D. L.; Desai, S.; Doel, P.; Eifler, T. F.; Evrard, A. E.; Fausti Neto, A.; Flaugher, B.; Fosalba, P.; Gaztanaga, E.; Gerdes, D.; Gruen, D.; Gruendl, R. A.; Honscheid, K.; James, D.; Kuropatkin, N.; Lahav, O.; Li, T. S.; Maia, M. A. G.; Makler, M.; Marshall, J.; Miller, C. J.; Miquel, R.; Ogando, R.; Plazas, A. A.; Roodman, A.; Sanchez, E.; Scarpine, V.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, R. C.; Soares-Santos, M.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thaler, J.; Walker, A. R.

    2015-09-01

    The Australian Dark Energy Survey (OzDES) is a five-year, 100-night, spectroscopic survey on the Anglo-Australian Telescope, whose primary aim is to measure redshifts of approximately 2500 Type Ia supernovae host galaxies over the redshift range 0.1 < z < 1.2, and derive reverberation-mapped black hole masses for approximately 500 active galactic nuclei and quasars over 0.3 < z < 4.5. This treasure trove of data forms a major part of the spectroscopic follow-up for the Dark Energy Survey for which we are also targeting cluster galaxies, radio galaxies, strong lenses, and unidentified transients, as well as measuring luminous red galaxies and emission line galaxies to help calibrate photometric redshifts. Here, we present an overview of the OzDES programme and our first-year results. Between 2012 December and 2013 December, we observed over 10 000 objects and measured more than 6 000 redshifts. Our strategy of retargeting faint objects across many observing runs has allowed us to measure redshifts for galaxies as faint as mr = 25 mag. We outline our target selection and observing strategy, quantify the redshift success rate for different types of targets, and discuss the implications for our main science goals. Finally, we highlight a few interesting objects as examples of the fortuitous yet not totally unexpected discoveries that can come from such a large spectroscopic survey.

  17. OzDES multifibre spectroscopy for the Dark Energy Survey: First-year operation and results

    SciTech Connect

    Yuan, Fang

    2015-07-29

    The Australian Dark Energy Survey (OzDES) is a five-year, 100-night, spectroscopic survey on the Anglo-Australian Telescope, whose primary aim is to measure redshifts of approximately 2500 Type Ia supernovae host galaxies over the redshift range 0.1 < z < 1.2, and derive reverberation-mapped black hole masses for approximately 500 active galactic nuclei and quasars over 0.3 < z < 4.5. This treasure trove of data forms a major part of the spectroscopic follow-up for the Dark Energy Survey for which we are also targeting cluster galaxies, radio galaxies, strong lenses, and unidentified transients, as well as measuring luminous red galaxies and emission line galaxies to help calibrate photometric redshifts. Here, we present an overview of the OzDES programme and our first-year results. Between 2012 December and 2013 December, we observed over 10 000 objects and measured more than 6 000 redshifts. Our strategy of retargeting faint objects across many observing runs has allowed us to measure redshifts for galaxies as faint as mr = 25 mag. We outline our target selection and observing strategy, quantify the redshift success rate for different types of targets, and discuss the implications for our main science goals. In conclusion, we highlight a few interesting objects as examples of the fortuitous yet not totally unexpected discoveries that can come from such a large spectroscopic survey.

  18. Partner notification for control of HIV: results after 2 years of a statewide program in Utah.

    PubMed Central

    Pavia, A T; Benyo, M; Niler, L; Risk, I

    1993-01-01

    OBJECTIVES. We sought to evaluate the utility of partner notification for control of human immunodeficiency virus (HIV) infection and to identify subgroups in which it may be most effective. METHODS. All persons reported to be HIV-positive during a 2-year period were interviewed. Outcome measures included proportion of index patients cooperating; number of partners named, located, counseled, and tested; number of persons newly testing positive; and costs. RESULTS. Of 308 index patients, 244 (79%) cooperated. They named 890 partners; 499 (70%) of in-state partners were located. Of these, 154 (34%) had previously tested HIV-positive. Of 279 partners tested for the first time, 39 (14%) were HIV-positive. Injecting drug users were significantly more likely to cooperate than persons in other risk groups (93% vs 76%) and named more partners (median 4 vs 1). Women and persons choosing confidential testing were more likely to cooperate and named more partners. The estimated cost of the program was $62,500 per year. CONCLUSIONS. Partner notification identified a group with a high seroprevalence of HIV. It was not successful among populations that may be difficult to reach with other interventions. PMID:8214231

  19. Fourteen Thousand Solar Systems and Growing: Results From the Starchitect Online Game at One Year

    NASA Astrophysics Data System (ADS)

    Harold, J. B.

    2015-12-01

    Starchitect (www.starchitect.net) is an online, end-to-end stellar and planetary evolution game designed to teach players about a variety of astronomy and planetary topics. Supported by NASA and NSF, and developed at the National Center for Interactive Learning at the Space Science Institute, the game uses the "sporadic play" model of games such as Farmville, where players might only take actions a few times a day, but continue playing for months. This framework is a natural fit for teaching about the evolution of stars and planets. Starchitect's systems evolve at a million years a minute, so that while massive stars will supernova almost immediately, lower mass stars like our sun will live for weeks of game time, possibly evolving life before passing through a red giant stage and ending their lives as white dwarfs. The game has now been live for over a year, playable both on Facebook and externally, and over 14,000 solar systems have been created by over 11,000 players. Since the game itself is heavily instrumented we now have access to a wealth of data that can be used to examine how people are playing the game and what tasks they are successfully engaging with. Through an embedded quiz game we are even in the position to assess the prior knowledge of our audience and execute pre/post assessments tied to game play. This paper will briefly describe the game and its educational strategies, then summarize some of our current results.

  20. OzDES multifibre spectroscopy for the Dark Energy Survey: First-year operation and results

    DOE PAGES

    Yuan, Fang

    2015-07-29

    The Australian Dark Energy Survey (OzDES) is a five-year, 100-night, spectroscopic survey on the Anglo-Australian Telescope, whose primary aim is to measure redshifts of approximately 2500 Type Ia supernovae host galaxies over the redshift range 0.1 < z < 1.2, and derive reverberation-mapped black hole masses for approximately 500 active galactic nuclei and quasars over 0.3 < z < 4.5. This treasure trove of data forms a major part of the spectroscopic follow-up for the Dark Energy Survey for which we are also targeting cluster galaxies, radio galaxies, strong lenses, and unidentified transients, as well as measuring luminous red galaxiesmore » and emission line galaxies to help calibrate photometric redshifts. Here, we present an overview of the OzDES programme and our first-year results. Between 2012 December and 2013 December, we observed over 10 000 objects and measured more than 6 000 redshifts. Our strategy of retargeting faint objects across many observing runs has allowed us to measure redshifts for galaxies as faint as mr = 25 mag. We outline our target selection and observing strategy, quantify the redshift success rate for different types of targets, and discuss the implications for our main science goals. In conclusion, we highlight a few interesting objects as examples of the fortuitous yet not totally unexpected discoveries that can come from such a large spectroscopic survey.« less

  1. Biofilm formation and control in a simulated spacecraft water system - Three year results

    NASA Technical Reports Server (NTRS)

    Schultz, John R.; Flanagan, David T.; Bruce, Rebekah J.; Mudgett, Paul D.; Carr, Sandra E.; Rutz, Jeffrey A.; Huls, M. H.; Sauer, Richard L.; Pierson, Duane L.

    1992-01-01

    Two simulated spacecraft water systems are being used to evaluate the effectiveness of iodine for controlling microbial contamination within such systems. An iodine concentration of about 2.0 mg/L is maintained in one system by passing ultrapure water through an iodinated ion exchange resin. Stainless steel coupons with electropolished and mechanically-polished sides are being used to monitor biofilm formation. Results after three years of operation show a single episode of significant bacterial growth in the iodinated system when the iodine level dropped to 1.9 mg/L. This growth was apparently controlled by replacing the iodinated ion exchange resin, thereby increasing the iodine level. The second batch of resin has remained effective in controlling microbial growth down to an iodine level of 1.0 mg/L. SEM indicates that the iodine has impeded but may have not completely eliminated the formation of biofilm. Metals analyses reveal some corrosion in the iodinated system after 3 years of continuous exposure. Significant microbial contamination has been present continuously in a parallel noniodinated system since the third week of operation.

  2. ATS-5 solar cell experiment results after one year in synchronous orbit

    NASA Technical Reports Server (NTRS)

    Anspaugh, B. E.

    1972-01-01

    The results of the ATS-5 solar cell experiment after one year in synchronous orbit are reported. A partial failure in the experimental electronics package has caused a loss of data from half the 80 experimental solar cells. Procedures for extracting data due to a partial spacecraft failure are described and discussed. Data from the remaining 40 solar cells, including 15 mounted on a thin flexible structure are analyzed. Data are corrected to a solar intensity of 140 mW/sq cm and a temperature of 25 C. It was found that after one year in synchronous orbit: (1) cells with 1.52-mm-thick coverslides did not show a clear-cut advantage over those with 0.15-mm coverslides, (2) cells with solderless grid lines are degrading at the same rate as are cells with solder-dipped grid lines, (3) cells not quite completely covered with coverslides suffered a large power loss in comparison to cells fully covered, (4) no clear-cut advantage of 10-cm cells over 2-cm cells has yet been observed, (5) cells mounted on the flexible panel with relatively little backshielding did not degrade any faster than those with substantial backshielding, and (6) the flight data in large part confirms the adequacy of the ground-based techniques used in our preflight radiation test program.

  3. Simulation of natural corrosion by vapor hydration test: seven-year results

    SciTech Connect

    Luo, J.S.; Ebert, W.L.; Mazer, J.J.; Bates, J.K.

    1996-12-31

    We have investigated the alteration behavior of synthetic basalt and SRL 165 borosilicate waste glasses that had been reacted in water vapor at 70 {degrees}C for time periods up to seven years. The nature and extent of corrosion of glasses have been determined by characterizing the reacted glass surface with optical microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive x-ray spectroscopy (EDS). Alteration in 70 {degrees}C laboratory tests was compared to that which occurs at 150-200 {degrees}C and also with Hawaiian basaltic glasses of 480 to 750 year old subaerially altered in nature. Synthetic basalt and waste glasses, both containing about 50 percent wt SiO{sub 2} were found to react with water vapor to form an amorphous hydrated gel that contained small amounts of clay, nearly identical to palagonite layers formed on naturally altered basaltic glass. This result implies that the corrosion reaction in nature can be simulated with a vapor hydration test. These tests also provide a means for measuring the corrosion kinetics, which are difficult to determine by studying natural samples because alteration layers have often spelled off the samples and we have only limited knowledge of the conditions under which alteration occurred.

  4. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study.

    PubMed Central

    Siewert, J R; Böttcher, K; Stein, H J; Roder, J D

    1998-01-01

    OBJECTIVE: In 1986 a prospective multicenter observation trial in patients with resected gastric cancer was initiated in Germany. An analysis of prognostic factors based on the 10-year survival data is now presented. PATIENTS AND METHODS: A total of 1654 patients treated for gastric cancer between 1986 and 1989 at 19 centers in Germany and Austria were included. The resected specimen were evaluated histopathologically according to a standardized protocol. The extent of lymphadenectomy was classified after surgery based on the number of removed lymph nodes on histopathologic assessment (25 or fewer removed nodes, D1 or standard lymphadenectomy; >25 removed nodes, D2 or extended lymphadenectomy). Endpoint of the study was death. Follow-up is complete for 97% of the included patients (median follow-up of the surviving patients is 8.4 years). Prognostic factors were assessed by multivariate analysis. RESULTS: A complete macroscopic and microscopic tumor resection (R0 resection according to the UICC 1997) could be achieved in 1182 of the 1654 patients (71.5%). The calculated 10-year survival rate in the entire patient population was 26.3% +/- 4.7%; it was 36.1% +/- 1.6% after an R0 resection. In the total patient population there was an independent prognostic effect of the ratio between invaded and removed lymph nodes, the residual tumor (R) category, the pT category, the presence of postsurgical complications, and the presence of distant metastases. Multivariate analysis in the subgroup of patients who had a UICC R0 resection confirmed the nodal status, the pT category, and the presence of postsurgical complications as the major independent prognostic factors. The extent of lymph node dissection had a significant and independent effect on the 10-year survival rate in patients with stage II tumors. This effect was present in the subgroups with (pT2N1) and without (pT3N0) lymph node metastases on standard histopathologic assessment. The beneficial effect of extended

  5. Observing Global Ocean Circulation From Space: The First Year's Results From the TOPEX/POSEIDON Mission

    NASA Technical Reports Server (NTRS)

    Fu, L. -L.

    1993-01-01

    The joint U.S./France TOPEX/Poseidon satellite was launched on August 10, 1992, and became operational 42 days later. The major goal of the mission is to use a radar altimeter system for making precise measurements of the height of the sea surface for the study of the dynamics of large-scale ocean circulation, which is a key to understanding global climate change. Additionally, the data are used for studying ocean tides and marine geophysics. The radar altimeter also measures wave height and wind speed. The mission is being conducted to optimize the sea surface height measurements for a minimum of three years. The primary objective of the first six months of the mission was to calibrate and validate the mission's measurements. The verification results indicate that all the measurement objectives have been met...

  6. Summary results from the NASA Tech House one year live-in

    NASA Technical Reports Server (NTRS)

    Hamlet, I. L.

    1979-01-01

    The NASA Tech House was designed and constructed at the Langley Research Center, Hampton, Va., to demonstrate and evaluate new technology potentially applicable for conservation of energy and resources and for improvements in safety and security in a single-family residence. All technology items, including solar energy systems and a waste water reuse system, were evaluated under actual living conditions for a one-year period with a family of four living in the house in their normal life style. Results are presented which show overall savings in energy and resources compared to requirements for a defined similar conventional house under the same conditions. Also included are general operational experience and performance data for all the various items and systems of technology incorporated into the house design.

  7. Streptococcus Endophthalmitis Outbreak after Intravitreal Injection of Bevacizumab: One-year Outcomes and Investigative Results

    PubMed Central

    Goldberg, Roger A.; Flynn, Harry W.; Miller, Darlene; Gonzalez, Serafin; Isom, Ryan F.

    2013-01-01

    Purpose To report the one-year clinical outcomes of an outbreak of Streptococcus endophthalmitis after intravitreal injection of bevacizumab, including visual acuity outcomes, microbiological testing and compound pharmacy investigations by the Food and Drug Administration (FDA). Design Retrospective consecutive case series. Participants 12 eyes of 12 patients who developed endophthalmitis after receiving intravitreal bevacizumab prepared by a single compounding pharmacy. Methods Medical records of patients were reviewed; phenotypic and DNA analyses were performed on microbes cultured from patients and from unused syringes. An inspection report by the FDA based on site-visits to the pharmacy that prepared the bevacizumab syringes was summarized. Main Outcome Measures Visual acuity, interventions received, time-to-intervention; microbiological consistency; FDA inspection findings. Results Between July 5 and July 8, 2011, 12 patients developed endophthalmitis after intravitreal bevacizumab from syringes prepared by a single compounding pharmacy. All patients received initial vitreous tap and injection, and eight (67%) subsequently underwent pars plana vitrectomy (PPV). After twelve months follow-up, outcomes have been poor: 7 patients (58%) required evisceration or enucleation, and only one patient regained pre-injection visual acuity. Molecular testing using real time polymerase chain reaction, partial sequencing of the groEL gene, and multilocus sequencing of 7 housekeeping genes confirmed the presence of a common strain of Streptococcus mitis/oralis in vitreous specimens and seven unused syringes prepared by the compounding pharmacy at the same time. An FDA investigation of the compounding pharmacy noted deviations from standard sterile technique, inconsistent documentation, and inadequate testing of equipment required for safe preparation of medications. Conclusions In this outbreak of endophthalmitis, outcomes have been generally poor and PPV did not improve

  8. Results of Detailed Hydrologic Characterization Tests—Fiscal and Calendar Year 2005

    SciTech Connect

    Spane, Frank A.; Newcomer, Darrell R.

    2008-02-27

    This report provides the results of detailed hydrologic characterization tests conducted within selected Hanford Site wells during fiscal and calendar year 2005. Detailed characterization tests performed included groundwater-flow characterization, barometric response evaluation, slug tests, in-well vertical groundwater-flow assessments, and a single-well tracer and constant-rate pumping test. Hydraulic property estimates obtained from the detailed hydrologic tests include hydraulic conductivity, transmissivity, specific yield, effective porosity, in-well lateral and vertical groundwater-flow velocity, aquifer groundwater-flow velocity, and depth-distribution profiles of hydraulic conductivity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for a site where detailed well testing was performed. Results obtained from these tests provide hydrologic information that supports the needs of Resource Conservation and Recovery Act waste management area characterization as well as sitewide groundwater monitoring and modeling programs. These results also reduce the uncertainty of groundwater-flow conditions at selected locations on the Hanford Site.

  9. A Five-Year Analysis of MODIS NDVI and NDWI for Rangeland Drought Assessment: Preliminary Results

    NASA Astrophysics Data System (ADS)

    Gu, Y.; Brown, J. F.; Verdin, J. P.; Wardlow, B.

    2006-12-01

    Drought is one of the most costly natural disasters in the United States. Traditionally, drought monitoring has been based on weather station observations, which lack the continuous spatial coverage needed to adequately characterize and monitor detailed spatial patterns of drought conditions. Satellite remote sensing observations can provide a synoptic view of the land and provide a spatial context for measuring drought. A common satellite-based index, the normalized difference vegetation index (NDVI) has a 30-year history of use for vegetation condition monitoring. NDVI is calculated from the visible red and near infrared channels and measures the changes in chlorophyll absorption and reflection in the spongy mesophyll of the vegetation canopy that are reflected in these respective bands. The normalized difference water index (NDWI) is another index, derived from the near-infrared and short wave infrared channels, and reflects changes in both the water content and spongy mesophyll in the vegetation canopy. As a result, the NDWI is influenced by both desiccation and wilting in the vegetation canopy and may be a more sensitive indicator than the NDVI for large- area drought monitoring. The objective of this study was to process and evaluate a 5-year history of 500-meter NDVI and NDWI data derived from the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument and to investigate methods for measuring and monitoring drought in rangeland over the southern plains of the United States. This initial study included: (1) the development of a climatological database for MODIS NDVI and NDWI, (2) a study of the relationship between the NDVI, NDWI, and drought condition over rangeland, (3) the development of a method to provide threshold NDVI/NDWI values under drought conditions based on the 5-year NDVI/NDWI/drought condition analysis, and (4) the investigation of additional vegetation drought information provided by the NDWI versus the NDVI in a 5-year comparison of

  10. The effects of Crew Resource Mangement (CRM) training in airline maintenance: Results following three years' experience

    NASA Technical Reports Server (NTRS)

    Taylor, J. C.; Robertson, M. M.

    1995-01-01

    This report describes three years' evaluation of the effects of one airline's Crew Resources Management (CRM) training operation for maintenance. This evaluation focuses on the post-training attitudes of maintenance managers' and technical support professionals, their reported behaviors, and the safety, efficiency and dependable maintenance performance of their units. The results reveal a strong positive effect of the training. The overall program represents the use of CRM training as a long-term commitment to improving performance through effective communication at all levels in airline maintenance operations. The initial findings described in our previous progress reports are reinforced and elaborated here. The current results benefit from the entire pre-post training survey, which now represents total attendance of all managers and staff professionals. Additionally there are now full results from the two-month, six-month, and 12-month follow-up questionnaires, together with as many as 33 months of post-training performance data, using several indicators. In this present report, we examine participants' attitudes, their reported behaviors following the training, the performance of their work units, and the relationships among these variables. Attitudes include those measured immediately before and after the training as well as participants' attitudes months after their training. Performance includes measures, by work units, of on-time flight departures, on-schedule maintenance releases, occupational and aircraft safety, and efficient labor costs. We report changes in these performance measures following training, as well their relationships with the training participants' attitudes. Highlights of results from this training program include increased safety and improved costs associated with positive attitudes about the use of more assertive communication, and the improved management of stress. Improved on-time performance is also related to those improved

  11. The Functional Task Test: Results from the One-Year Mission

    NASA Technical Reports Server (NTRS)

    Bloomberg, J. J; Batson, C. D.; Buxton, R. E.; Feiveson, A. H.; Kofman, I. S.; Laurie, S.; Lee, S. M. C.; Miller, C. A.; Mulavara, A. P.; Peters, B. T.; May-Phillips, T.; Ploutz-Snyder, L. L.; Reschke, M. F.; Ryder, J. W.; Stenger, M. B.; Taylor, L. C.; Wood, S. J.

    2017-01-01

    landing. The FTT one-year results will be presented at the meeting, and a comparison will be made with data previously obtained using the same protocol on astronauts tested before and after 6 months in space. Future work will focus on collecting data from additional subjects from one-year flights to gain a better assessment of extreme long-duration exposure to spaceflight on both functional measure of performance and physiological metrics.

  12. Final Results from Three Years of Observations with the BICEP Telescope

    NASA Astrophysics Data System (ADS)

    Bischoff, Colin

    2013-04-01

    The BICEP (Background Imaging of Cosmic Extragalactic Polarization) telescope is the first instrument designed specifically to search for the signature of inflation using the polarization of the Cosmic Microwave Background at degree angular scales. BICEP combines polarization sensitive bolometers, operating at 100 and 150 GHz, with a small aperture cryogenic refracting telescope. It operated for three seasons from 2006 through 2008 at the Amundsen-Scott South Pole Station. Results from the first two seasons, published in Chiang et al. (2010), have so far provided the tightest upper limits on B-mode polarization of the CMB. We report on new results that incorporate the full three year data set to improve this constraint. Besides including more data, the new analysis uses a novel method to deproject the dominant source of systematic contamination in BICEP data. The successful design of BICEP is the basis of BICEP2, which operated at the South Pole from 2010 through 2012, and the Keck Array, which began observations in 2011 and is still operating. These experiments are currently producing extremely deep maps of CMB polarization.

  13. Results of 1 year of clinical experience with independent dose calculation software for VMAT fields

    PubMed Central

    Colodro, Juan Fernando Mata; Berna, Alfredo Serna; Puchades, Vicente Puchades; Amores, David Ramos; Baños, Miguel Alcaraz

    2014-01-01

    It is widely accepted that a redundant independent dose calculation (RIDC) must be included in any treatment planning verification procedure. Specifically, volumetric modulated arc therapy (VMAT) technique implies a comprehensive quality assurance (QA) program in which RIDC should be included. In this paper, the results obtained in 1 year of clinical experience are presented. Eclipse from Varian is the treatment planning system (TPS), here in use. RIDC were performed with the commercial software; Diamond® (PTW) which is capable of calculating VMAT fields. Once the plan is clinically accepted, it is exported via Digital Imaging and Communications in Medicine (DICOM) to RIDC, together with the body contour, and then a point dose calculation is performed, usually at the isocenter. A total of 459 plans were evaluated. The total average deviation was -0.3 ± 1.8% (one standard deviation (1SD)). For higher clearance the plans were grouped by location in: Prostate, pelvis, abdomen, chest, head and neck, brain, stereotactic radiosurgery, lung stereotactic body radiation therapy, and miscellaneous. The highest absolute deviation was -0.8 ± 1.5% corresponding to the prostate. A linear fit between doses calculated by RIDC and by TPS produced a correlation coefficient of 0.9991 and a slope of 1.0023. These results are very close to those obtained in the validation process. This agreement led us to consider this RIDC software as a valuable tool for QA in VMAT plans. PMID:25525309

  14. Results of 1 year of clinical experience with independent dose calculation software for VMAT fields.

    PubMed

    Colodro, Juan Fernando Mata; Berna, Alfredo Serna; Puchades, Vicente Puchades; Amores, David Ramos; Baños, Miguel Alcaraz

    2014-10-01

    It is widely accepted that a redundant independent dose calculation (RIDC) must be included in any treatment planning verification procedure. Specifically, volumetric modulated arc therapy (VMAT) technique implies a comprehensive quality assurance (QA) program in which RIDC should be included. In this paper, the results obtained in 1 year of clinical experience are presented. Eclipse from Varian is the treatment planning system (TPS), here in use. RIDC were performed with the commercial software; Diamond(®) (PTW) which is capable of calculating VMAT fields. Once the plan is clinically accepted, it is exported via Digital Imaging and Communications in Medicine (DICOM) to RIDC, together with the body contour, and then a point dose calculation is performed, usually at the isocenter. A total of 459 plans were evaluated. The total average deviation was -0.3 ± 1.8% (one standard deviation (1SD)). For higher clearance the plans were grouped by location in: Prostate, pelvis, abdomen, chest, head and neck, brain, stereotactic radiosurgery, lung stereotactic body radiation therapy, and miscellaneous. The highest absolute deviation was -0.8 ± 1.5% corresponding to the prostate. A linear fit between doses calculated by RIDC and by TPS produced a correlation coefficient of 0.9991 and a slope of 1.0023. These results are very close to those obtained in the validation process. This agreement led us to consider this RIDC software as a valuable tool for QA in VMAT plans.

  15. Bioventing results in significant reduction of diesel fuel contamination after one year

    SciTech Connect

    Baker, J.N.; Nickerson, D.A.; Guest, P.R.

    1994-12-31

    A bioventing system was designed and installed to enhance the natural biodegradation of residual diesel fuel contaminated soils at an underground storage tank (UST) facility in Seattle, Washington. This system was designed to operate in conjunction with an existing total fluids recovery system to expose more heavily contaminated soils at the capillary fringe to injected air. A pilot study conducted at the facility indicated that an initial biodegradation rate of 2,200 milligrams of total petroleum hydrocarbons (TPH) per kiligram of soil per year could be achieved, making bioventing a feasible remedial alternative to accelerate site cleanup. Remediation costs were reduced by installing horizontal piping arrangements at the bottom of two separate tank pit excavations during the scheduled fueling system closures. Unlike single point injection wells, this innovative system design results in a wider area of influence by creating two aerated beds through which air is dispersed into the surrounding formation. As a result, less pressure is required to distribute air in the variably permeable site soils, minimizing subsurface vapor migration. The areas of greatest contamination in the capillary fringe are directly impacted by placing impermeable caps over the aerated beds.

  16. Accelerated Corneal Collagen Cross-Linking in Pediatric Patients: Two-Year Follow-Up Results

    PubMed Central

    Shetty, Rohit; Nagaraja, Harsha; Jayadev, Chaitra; Pahuja, Natasha Kishore; Kurian Kummelil, Mathew; Nuijts, Rudy M. M. A.

    2014-01-01

    Purpose. To evaluate the effectiveness and safety of accelerated corneal collagen cross-linking (ACXL) in patients below 14 years of age with progressive keratoconus. Materials and Methods. Thirty eyes of 18 patients with established progressive keratoconus underwent preoperative and postoperative visual acuity assessment, topography, and specular microscopy prior to ACXL and were followed up for 24 months. Results. Mean age of the patients was 12.7 years with ten males and eight females. There was an improvement in the mean postoperative uncorrected distant visual acuity (from 0.76 ± 0.26 to 0.61 ± 0.25; P = 0.005), mean corrected distant visual acuity (from 0.24 ± 0.19 to 0.12 ± 0.12; P < 0.001), mean spherical refraction (from −3.04 DS ± 3.60 to −2.38 DS ± 3.37; P = 0.28), mean cylinder (from −3.63 DC ± 1.82 to −2.80 DC ± 1.48; P = 0.008), and spherical equivalent (from −4.70 D ± 3.86 to −3.75 D ± 3.49; P = 0.15). Three eyes of two patients with vernal keratoconjunctivitis (VKC) showed progression. There were no intra- or postoperative complications. Conclusion. In pediatric patients ACXL is an effective and safe procedure for the management of keratoconus. Optimal management of VKC is important to arrest the progression of keratoconus. PMID:25295278

  17. Stereopsis Results at 4.5 Years of Age in the Infant Aphakia Treatment Study

    PubMed Central

    Hartmann, E. Eugenie; Stout, Ann U.; Lynn, Michael J.; Yen, Kimberly G.; Kruger, Stacey J.; Lambert, Scott R.

    2014-01-01

    Purpose To determine whether stereopsis of infants treated for monocular cataracts varies with the type of optical correction used. Design Randomized prospective clinical trial Methods The Infant Aphakia Treatment Study randomized 114 patients with unilateral cataracts at age 1 to 7 months to either primary intraocular lens (IOL) or contact lens correction. At 4.5 years of age a masked examiner assessed stereopsis on these patients using three different tests: 1) Frisby; 2) Randot Preschool; and 3) Titmus fly. Results Twenty-eight patients (25%) had a positive response to at least one of the stereopsis tests. There was no statistically significant difference in stereopsis between the two treatment groups. Frisby (contact lens, 6 (11%); IOL, 7 (13%); p=0.99), Randot (contact lens, 3 (6%); IOL, 1 (2%); p=0.62) or Titmus: (contact lens, 8 (15%); IOL, 13 (23%); p=0.34). The median age at surgery for patients with stereopsis was younger than for those without stereopsis (1.2 versus 2.4 months; p=0.002). The median visual acuity for patients with stereopsis was better than for those without stereopsis (20/40 vs. 20/252; p=0.0003). Conclusion The type of optical correction did not influence stereopsis outcomes. However, two other factors did: age at surgery and visual acuity in the treated eye at age 4.5 years. Early surgery for unilateral congenital cataract and the presence of visual acuity better than or equal to 20/40 appear to be more important than the type of initial optical correction used for the development of stereopsis. PMID:25261241

  18. Global surgery in a postconflict setting - 5-year results of implementation in the Russian North Caucasus.

    PubMed

    Lunze, Fatima I; Lunze, Karsten; Tsorieva, Zemfira M; Esenov, Constantin T; Reutov, Alexandr; Eichhorn, Thomas; Offergeld, Christian

    2015-01-01

    Background Collaborations for global surgery face many challenges to achieve fair and safe patient care and to build sustainable capacity. The 2004 terrorist attack on a school in Beslan in North Ossetia in the Russian North Caucasus left many victims with complex otologic barotrauma. In response, we implemented a global surgery partnership between the Vladikavkaz Children's Hospital, international surgical teams, the North Ossetian Health Ministry, and civil society organizations. This study's aim was to describe the implementation and 5-year results of capacity building for complex surgery in a postconflict, mid-income setting. Design We conducted an observational study at the Children's Hospital in Vladikavkaz in the autonomous Republic of North Ossetia-Alania, part of the Russian Federation. We assessed the outcomes of 15 initial patients who received otologic surgeries for complex barotrauma resulting from the Beslan terrorism attack and for other indications, and report the incidence of intra- and postoperative complications. Results Patients were treated for trauma related to terrorism (53%) and for indications not related to violence (47%). None of the patients developed peri- or postoperative complications. Three patients (two victims of terrorism) who underwent repair of tympanic perforations presented with re-perforations. Four junior and senior surgeons were trained on-site and in Germany to perform and teach similar procedures autonomously. Conclusions In mid-income, postconflict settings, complex surgery can be safely implemented and achieve patient outcomes comparable to global standards. Capacity building can build on existing resources, such as operation room management, nursing, and anesthesia services. In postconflict environments, substantial surgical burden is not directly attributable to conflict-related injury and disease, but to health systems weakened by conflicts. Extending training and safe surgical care to include specialized

  19. In vivo dosimetry for total body irradiation: five-year results and technique comparison.

    PubMed

    Patel, Reshma P; Warry, Alison J; Eaton, David J; Collis, Christopher H; Rosenberg, Ivan

    2014-07-08

    The aim of this work is to establish if the new CT-based total body irradiation (TBI) planning techniques used at University College London Hospital (UCLH) and Royal Free Hospital (RFH) are comparable to the previous technique at the Middlesex Hospital (MXH) by analyzing predicted and measured diode results. TBI aims to deliver a homogeneous dose to the entire body, typically using extended SSD fields with beam modulation to limit doses to organs at risk. In vivo dosimetry is used to verify the accuracy of delivered doses. In 2005, when the Middlesex Hospital was decommissioned and merged with UCLH, both UCLH and the RFH introduced updated CT-planned TBI techniques, based on the old MXH technique. More CT slices and in vivo measurement points were used by both; UCLH introduced a beam modulation technique using MLC segments, while RFH updated to a combination of lead compensators and bolus. Semiconductor diodes were used to measure entrance and exit doses in several anatomical locations along the entire body. Diode results from both centers for over five years of treatments were analyzed and compared to the previous MXH technique for accuracy and precision of delivered doses. The most stable location was the field center with standard deviations of 4.1% (MXH), 3.7% (UCLH), and 1.7% (RFH). The least stable position was the ankles. Mean variation with fraction number was within 1.5% for all three techniques. In vivo dosimetry can be used to verify complex modulated CT-planned TBI, and demonstrate improvements and limitations in techniques. The results show that the new UCLH technique is no worse than the previous MXH one and comparable to the current RFH technique.

  20. Results For The Third Quarter Calendar Year 2016 Tank 50H Salt Solution Sample

    SciTech Connect

    Crawford, C.

    2016-10-13

    In this memorandum, the chemical and radionuclide contaminant results from the Third Quarter Calendar Year 2016 (CY16) sample of Tank 50H salt solution are presented in tabulated form. The Third Quarter CY16 Tank 50H samples (a 200 mL sample obtained 6” below the surface (HTF-5-16-63) and a 1 L sample obtained 66” from the tank bottom (HTF-50-16-64)) were obtained on July 14, 2016 and received at Savannah River National Laboratory (SRNL) on the same day. Prior to obtaining the samples from Tank 50H, a single pump was run at least 4.4 hours, and the samples were pulled immediately after pump shut down. The information from this characterization will be used by Defense Waste Processing Facility (DWPF) & Saltstone Facility Engineering for the transfer of aqueous waste from Tank 50H to the Saltstone Production Facility, where the waste will be treated and disposed of in the Saltstone Disposal Facility. This memorandum compares results, where applicable, to Saltstone Waste Acceptance Criteria (WAC) limits and targets. Data pertaining to the regulatory limits for Resource Conservation and Recovery Act (RCRA) metals will be documented at a later time per the Task Technical and Quality Assurance Plan (TTQAP) for the Tank 50H saltstone task. The chemical and radionuclide contaminant results from the characterization of the Third Quarter CY16 sampling of Tank 50H were requested by Savannah River Remediation (SRR) personnel and details of the testing are presented in the SRNL TTQAP.

  1. Global surgery in a postconflict setting - 5-year results of implementation in the Russian North Caucasus

    PubMed Central

    Lunze, Fatima I.; Lunze, Karsten; Tsorieva, Zemfira M.; Esenov, Constantin T.; Reutov, Alexandr; Eichhorn, Thomas; Offergeld, Christian

    2015-01-01

    Background Collaborations for global surgery face many challenges to achieve fair and safe patient care and to build sustainable capacity. The 2004 terrorist attack on a school in Beslan in North Ossetia in the Russian North Caucasus left many victims with complex otologic barotrauma. In response, we implemented a global surgery partnership between the Vladikavkaz Children's Hospital, international surgical teams, the North Ossetian Health Ministry, and civil society organizations. This study's aim was to describe the implementation and 5-year results of capacity building for complex surgery in a postconflict, mid-income setting. Design We conducted an observational study at the Children's Hospital in Vladikavkaz in the autonomous Republic of North Ossetia-Alania, part of the Russian Federation. We assessed the outcomes of 15 initial patients who received otologic surgeries for complex barotrauma resulting from the Beslan terrorism attack and for other indications, and report the incidence of intra- and postoperative complications. Results Patients were treated for trauma related to terrorism (53%) and for indications not related to violence (47%). None of the patients developed peri- or postoperative complications. Three patients (two victims of terrorism) who underwent repair of tympanic perforations presented with re-perforations. Four junior and senior surgeons were trained on-site and in Germany to perform and teach similar procedures autonomously. Conclusions In mid-income, postconflict settings, complex surgery can be safely implemented and achieve patient outcomes comparable to global standards. Capacity building can build on existing resources, such as operation room management, nursing, and anesthesia services. In postconflict environments, substantial surgical burden is not directly attributable to conflict-related injury and disease, but to health systems weakened by conflicts. Extending training and safe surgical care to include specialized

  2. Results-Based Financing in Mozambique’s Central Medical Store: A Review After 1 Year

    PubMed Central

    Spisak, Cary; Morgan, Lindsay; Eichler, Rena; Rosen, James; Serumaga, Brian; Wang, Angela

    2016-01-01

    ABSTRACT Background: Public health commodity supply chains are typically weak in low-income countries, partly because they have many disparate yet interdependent functions and components. Approaches to strengthening supply chains in such settings have often fallen short—they address technical weaknesses, but not the incentives that motivate staff to perform better. Methods: We reviewed the first year of a results-based financing (RBF) program in Mozambique, which began in January 2013. The program aimed to improve the performance of the central medical store—Central de Medicamentos e Artigos Medicos (CMAM)—by realigning incentives. We completed in-depth interviews and focus group discussions with 33 key informants, including representatives from CMAM and donor agencies, and collected quantitative data on performance measures and use of funds. Implementation: The RBF agreement linked CMAM performance payments to quarterly results on 5 performance indicators related to supply planning, distribution planning, and warehouse management. RBF is predicated on the theory that a combination of carrot and stick—i.e., shared financial incentives, plus increased accountability for results—will spur changes in behavior. Important design elements: (1) indicators were measured against quarterly targets, and payments were made only for indicators that met those targets; (2) targets were set based on documented performance, at levels that could be reasonably attained, yet pushed for improvement; (3) payment was shared with and dependent on all staff, encouraging teamwork and collaboration; (4) results were validated by verifiable data sources; and (5) CMAM had discretion over how to use the funds. Findings: We found that CMAM’s performance continually improved over baseline and that CMAM achieved many of its performance targets, for example, timely submission of quarterly supply and distribution planning reports. Warehouse indicators, such as inventory management and

  3. Amphetamines and cannabinoids testing in hair: Evaluation of results from a two-year period.

    PubMed

    Burgueño, María José; Alonso, Amaya; Sánchez, Sergio

    2016-08-01

    This paper presents an overview of a set of amphetamines and cannabinoids tests performed on head hair samples from the Medico-Legal sector at the Madrid Department of the Spanish National Institute of Toxicology and Forensic Sciences during the years 2013 and 2014. The hair samples were tested for five stimulant phenylalkylamine derivatives -amphetamine (AP), methamphetamine (MA), 3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxy-amphetamine (MDA), and 3,4-methylenedioxy-N-ethylamphetamine (MDEA)- and/or two cannabinoids-Δ(9)-tetrahydrocannabinol (THC) and cannabinol (CBN)- by gas chromatography equipped with mass spectrometry detection in selected-ion monitoring mode, applying a method accredited to ISO/IEC 17025 standards. The test results were interpreted according to the confirmation cut-offs proposed by the Society of Hair Testing (SoHT) to identify chronic drug use. The ratios of positive results were studied in relation to gender, age, hair colour, dyeing and length of the tested samples to assess the independence from these variables or the association with them. Low, medium and high ranges of concentration were also estimated for each drug. 21.94% of the 2954 hair samples tested for phenylalkylamine derivatives were positive for one or more substances. 16.38% of the samples were positive for AP, 12.09% for MDMA and only 0.44% for MA. 6.60% of the tested samples were positive for AP/MDMA combination. A total of 3178 samples were tested for cannabinoids, resulting in 53.40% positive for THC and CBN. Simultaneous tests for phenylalkylamine derivatives and cannabinoids were performed in 2931 of the samples; 14.94% of them were positive for THC, CBN, and one or more amphetamines. According to the results from the statistical analysis, the use of THC and MDMA vary with age and gender among the Medico-Legal sector in an extended area of Spain, while the use of AP appears to be independent of these variables. On the other hand, the results of THC in

  4. Five-Year Wilkinson Microwave Anisotropy Probe Observations: Data Processing, Sky Maps, and Basic Results

    NASA Technical Reports Server (NTRS)

    Hinshaw, G.; Weiland, J. L.; Hill, R. S.; Odegard, N.; Larson, D.; Bennett, C. L.; Dunkley, J.; Gold, B.; Greason, M. R.; Jarosik, N.; Komatsu, E.; Nolta, M. R.; Page, L.; Spergel, D. N.; Wollack, E.; Halpern, M.; Kogut, A.; Limon, M.; Meyer, S. S.; Tucker, G. S.; Wright, E. L.

    2010-01-01

    We present new full-sky temperature and polarization maps in five frequency bands from 23 to 94 GHz, based on data from the first five years of the Wilkinson Microwave Anisotropy Probe (WMAP) sky survey. The new maps are consistent with previous maps and are more sensitive. The five-year maps incorporate several improvements in data processing made possible by the additional years of data and by a more complete analysis of the instrument calibration and in-flight beam response. We present several new tests for systematic errors in the polarization data and conclude that W-band polarization data is not yet suitable for cosmological studies, but we suggest directions for further study. We do find that Ka-band data is suitable for use; in conjunction with the additional years of data, the addition of Ka band to the previously used Q- and V-band channels significantly reduces the uncertainty in the optical depth parameter, tau. Further scientific results from the five-year data analysis are presented in six companion papers and are summarized in Section 7 of this paper. With the five-year WMAP data, we detect no convincing deviations from the minimal six-parameter ACDM model: a flat universe dominated by a cosmological constant, with adiabatic and nearly scale-invariant Gaussian fluctuations. Using WMAP data combined with measurements of Type Ia supernovae and Baryon Acoustic Oscillations in the galaxy distribution, we find (68% CL uncertainties): OMEGA(sub b)h(sup 2) = 0.02267(sup +0.00058)(sub -0.00059), OMEGA(sub c)h(sup 2) = 0.1131 plus or minus 0.0034, OMEGA(sub logical and) = 0.726 plus or minus 0.015, ns = .960 plus or minus 0.013, tau = 0.84 plus or minus 0.016, and DELTA(sup 2)(sub R) = (22.445 plus or minus 0.096) x 10(exp -9) at k = 0.002 Mpc(exp -1). From these we derive sigma(sub 8) = 0.812 plus or minus 0.026, H(sub 0) = 70.5 plus or minus 1.3 kilometers per second Mpc(exp -1), OMEGA(sub b) = 0.0456 plus or minus 0.0015, OMEGA(sub c) = .228 plus or minus

  5. Negative symptom improvement during cognitive rehabilitation: results from a 2-year trial of Cognitive Enhancement Therapy.

    PubMed

    Eack, Shaun M; Mesholam-Gately, Raquelle I; Greenwald, Deborah P; Hogarty, Susan S; Keshavan, Matcheri S

    2013-08-30

    Cognitive rehabilitation has shown beneficial effects on cognition in patients with schizophrenia, which may also help to improve negative symptoms due to overlapping pathophysiology between these two domains. To better understand the possible relationship between these areas, we conducted an exploratory analysis of the effects of Cognitive Enhancement Therapy (CET) on negative symptoms. Early course schizophrenia outpatients (n=58) were randomized to 2 years of CET or an Enriched Supportive Therapy (EST) control condition. Results revealed significant and medium-sized (d=0.61) differential improvements favoring CET in overall negative symptoms, particularly social withdrawal, affective flattening, and motor retardation. Neurocognitive improvement was associated with reduced negative symptoms in CET, but not EST patients. No relationships were observed between improvements in emotion processing aspects of social cognition, as measured by the Mayer-Salovey-Caruso Emotional Intelligence Test, and negative symptoms. CET represents an effective cognitive rehabilitation intervention for schizophrenia that may also have benefits to negative symptoms. Future studies specifically designed to examine negative symptoms during the course of cognitive rehabilitation are needed.

  6. Cryobanking of Korean allium germplasm collections: results from a 10 year experience.

    PubMed

    Kim, H H; Popova, E; Shin, D J; Yi, J Y; Kim, C H; Lee, J S; Yoon, M K; Engelmann, F

    2012-01-01

    This paper reviews a 10-year experience in establishing a cryopreserved Allium germplasm collection at the genebank of the National Agrobiodiversity Center, Republic of Korea. A systematic approach to Allium cryopreservation included: 1. revealing the most critical factors that affected regeneration after cryostorage; 2. understanding the mechanisms of cryoprotection by analyzing the thermal behavior of explants and cryoprotectant solutions using DSC and influx/efflux of cryoprotectants using HPLC; 3. assessing genetic stability of regenerants; and 4. revealing the efficiency of cryotherapy. Bulbil primordia, i.e. asexual bulbs formed on unripe inflorescences, proved to be the most suitable material for conservation of bolting varieties due to high post-cryopreservation regrowth and lower microbial infection level, followed by apical shoot apices from single bulbs and cloves. A total of 1,158 accessions of garlic as well as some Allium species have been cryopreserved during 2005-2010 using the droplet-vitrification technique with a mean regeneration percentage of 65.9 percent after cryostorage. These results open the door for large-scale implementation of cryostorage and for simplifying international exchange for clonal Allium germplasm.

  7. What makes age diverse teams effective? Results from a six-year research program.

    PubMed

    Wegge, J; Jungmann, F; Liebermann, S; Shemla, M; Ries, B C; Diestel, S; Schmidt, K-H

    2012-01-01

    Based on a new model of productivity in age diverse tams, findings from a six-year research program are reported in which data from more than 745 natural teams with 8,848 employees in three different fields (car production, administrative work, financial services) were collected. Moreover, central assumptions of this model were tested with a representative survey of the German workforce (N = 2,000). Results support both significant advantages and disadvantages for age-mixed teams. Based on the findings, the following preconditions for the effectiveness of age diverse teams are identified: high task complexity, low salience and high appreciation of age diversity, a positive team climate, low age-discrimination, ergonomic design of work places, and the use of age differentiated leadership. Based on these insights, we developed a new training for supervisors, which addresses the aforementioned aspects and seeks to improve team performance and health of team members. It was found that the training reduces age stereotypes, team conflicts and enhances innovation. Thus, we can conclude that effective interventions for a successful integration of elderly employees in work groups are available and that combinations of measures that address ergonomic design issues, team composition and leadership are to be strongly recommended for practice.

  8. Developing a global psychotherapeutic approach to schizophrenia: results of a five-year follow-up.

    PubMed Central

    Alanen, Y. O.; Räkköläinen, V.; Rasimus, R.; Laakso, J.; Kaljonen, A.

    1985-01-01

    This is an account of a long-range action research project to determine indications for and effects of a comprehensive psychotherapeutic approach, including various treatment modalities, in the treatment of schizophrenics. Four diagnostic groups were established among the 100 patients. In the course of data analysis, the group of typical schizophrenics (56 percent) was contrasted to or compared with the entire series. A further diagnostic differentiation was established according to ego functioning; i.e., imminent, acute, regressive, and paranoid ego disintegrations, respectively. Patients and family members were interviewed upon admission, and again two and five years later, and the data recorded on a 163-item form from which 40 clinical and psychosocial variables were constructed after the baseline examinations. In addition to cross-tabulation, logistic regression analysis was employed. The conclusion that the follow-up study supports the effectiveness of our global psychotherapeutic approach to treating schizophrenia seems justified. Results so far indicate that five modes of therapy in addition to drug treatments are optimal for different patients. The five modes are long-term individual psychotherapy, couple or conjoint family therapy for married patients, family therapy with the family of origin, flexible short-term crisis intervention with a family focus, and extensive long-term treatment focused on social rehabilitation for the most ill-starred patients. PMID:4049919

  9. A 2-year young adult obesity prevention trial in the US: Process evaluation results.

    PubMed

    Laska, Melissa N; Sevcik, Sarah M; Moe, Stacey G; Petrich, Christine A; Nanney, Marilyn S; Linde, Jennifer A; Lytle, Leslie A

    2016-12-01

    Our objective was to conduct a process evaluation of the CHOICES (Choosing Healthy Options in College Environments and Settings) study, a large, randomized, controlled trial designed to prevent unhealthy weight gain in young adults (aged 18-35) attending 2-year community colleges in the USA. The 24-month intervention consisted of participation in an academic course and a social networking and support website. Among intervention participants, completion rates for most course activities were >80%, reflecting a high level of dose received. Course retention and participant satisfaction were also high. Engagement results, however, were mixed with less than half of participants in the online and hybrid sections of the course reporting that they interacted with course materials ≥3 h/week, but 50-75% reporting that they completed required lessons 'all/very thoroughly'. Engagement in the website activities was also mixed with more than half of intervention participants logging onto the website during the first month, but then declining to 25-40% during the following 23 months of the intervention. Intervention engagement is a challenge of online interventions and a challenge of working with the young adult age group in general. Additional research is needed to explore strategies to support engagement among this population, particularly for relatively long intervention durations.

  10. Ionosphere over Africa: Results from Geomagnetic Field Measurements During International Heliophysical Year IHY

    NASA Astrophysics Data System (ADS)

    Rabiu, A. B.; Yumoto, K.; Falayi, E. O.; Bello, O. R.; Magdas/Cpmn Group

    2011-12-01

    Space Environment Research Centre of Kyushu University, Japan, installed 13 units of Magnetic Data Acquisition Systems MAGDAS over Africa during the International Heliophysical Year IHY. Magnetic records from 10 stations along the African 96o Magnetic Meridian (Geographical 30° - 40° East) were examined for Solar quiet daily Sq variations in the two geomagnetic field components H and D. Latitudinal variations of Sq in the geomagnetic components were examined. Signatures of equatorial electrojet and worldwide Sq were identified and studied in detail. H field experienced more variation within the equatorial electrojet zone. Diurnal variations of the geomagnetic variations in the two components were discussed. Sq H is expectedly consistently maximum within the electrojet zone as a result of EEJ. Sq D has maximum values at about -20ɛ (sunrise), -10ɛ (noon time) and +10ɛ (sunset). Levels of inter-relationships between the Sq and its variability in the two components were statistically derived and interpreted in line with the mechanisms responsible for the variations of the geomagnetic field. Data from 2 magnetic observatories within equatorial electrojet EEJ strip and 2 stations outside the EEJ strip were employed to evaluate and study the signatures of the Equatorial electrojet over the African sector. The transient variations of the EEJ at two almost parallel axes using Lagos-Ilorin (West Africa) and Nairobi-Addis Ababa (East Africa) pairs were examined. The eastern electrojet appeared stronger than the western. The latitudinal and longitudinal profiles of the Sq were examined and inferences drawn from observed results were discussed.

  11. Semantic Web Services Challenge, Results from the First Year. Series: Semantic Web And Beyond, Volume 8.

    NASA Astrophysics Data System (ADS)

    Petrie, C.; Margaria, T.; Lausen, H.; Zaremba, M.

    Explores trade-offs among existing approaches. Reveals strengths and weaknesses of proposed approaches, as well as which aspects of the problem are not yet covered. Introduces software engineering approach to evaluating semantic web services. Service-Oriented Computing is one of the most promising software engineering trends because of the potential to reduce the programming effort for future distributed industrial systems. However, only a small part of this potential rests on the standardization of tools offered by the web services stack. The larger part of this potential rests upon the development of sufficient semantics to automate service orchestration. Currently there are many different approaches to semantic web service descriptions and many frameworks built around them. A common understanding, evaluation scheme, and test bed to compare and classify these frameworks in terms of their capabilities and shortcomings, is necessary to make progress in developing the full potential of Service-Oriented Computing. The Semantic Web Services Challenge is an open source initiative that provides a public evaluation and certification of multiple frameworks on common industrially-relevant problem sets. This edited volume reports on the first results in developing common understanding of the various technologies intended to facilitate the automation of mediation, choreography and discovery for Web Services using semantic annotations. Semantic Web Services Challenge: Results from the First Year is designed for a professional audience composed of practitioners and researchers in industry. Professionals can use this book to evaluate SWS technology for their potential practical use. The book is also suitable for advanced-level students in computer science.

  12. Sacroiliac Joint Fusion: One Year Clinical and Radiographic Results Following Minimally Invasive Sacroiliac Joint Fusion Surgery

    PubMed Central

    Kube, Richard A.; Muir, Jeffrey M.

    2016-01-01

    Background: Recalcitrant sacroiliac joint pain responds well to minimally-invasive surgical (MIS) techniques, although long-term radiographic and fusion data are limited. Objective: To evaluate the one-year clinical results from a cohort of patients with chronic sacroiliac (SI) joint pain unresponsive to conservative therapies who have undergone minimally invasive SI joint fusion. Methods: SI joint fusion was performed between May 2011 and January 2014. Outcomes included radiographic assessment of fusion status, leg and back pain severity via visual analog scale (VAS), disability via Oswestry Disability Index (ODI) and complication rate. Outcomes were measured at baseline and at follow-up appointments 6 months and 12 months post-procedure. Results: Twenty minimally invasive SI joint fusion procedures were performed on 18 patients (mean age: 47.2 (14.2), mean BMI: 29.4 (5.3), 56% female). At 12 months, the overall fusion rate was 88%. Back and leg pain improved from 81.7 to 44.1 points (p<0.001) and from 63.6 to 27.7 points (p=0.001), respectively. Disability scores improved from 61.0 to 40.5 (p=0.009). Despite a cohort containing patients with multiple comorbidities and work-related injuries, eight patients (50%) achieved the minimal clinically important difference (MCID) in back pain at 12 months, with 9 (69%) patients realizing this improvement in leg pain and 8 (57%) realizing the MCID in ODI scores at 12 months. No major complications were reported. Conclusion: Minimally invasive SI joint surgery is a safe and effective procedure, with a high fusion rate, a satisfactory safety profile and significant improvements in pain severity and disability reported through 12 months post-procedure. PMID:28144378

  13. Results of a Two-Year Longitudinal Study of Beverage-Specific Alcohol Use among Adolescents

    ERIC Educational Resources Information Center

    Moore, Michele Johnson; Werch, Chudley

    2007-01-01

    This study explored beverage-specific alcohol consumption patterns among a sample of high school students over a two-year period. Four hundred fifty-five students completed the validated questionnaire at all three time points (2002, 2003, 2004). Variables of interest included five use measures (past year use, 30-day frequency, quantity, heavy use,…

  14. A Consortium Project to Improve Retention and the First Year of College: Results and Recommendations

    ERIC Educational Resources Information Center

    Cutright, Marc

    2006-01-01

    This article examines the operation and perceived effectiveness of a short-term, nine-community-college consortium, a consortium dedicated to the improvement of student retention and first-year education at each of the colleges in the consortium. The consortium was composed of Alabama community colleges, essentially during calendar year 2002. Its…

  15. Experience with cinacalcet in primary hyperparathyroidism: results after 1 year of treatment

    PubMed Central

    García-Martín, Antonia; Luque-Pazos, Alessandra

    2013-01-01

    Objectives: To assess the characteristics of patients with primary hyperparathyroidism (PHPT) treated with cinacalcet and to evaluate its efficacy in reducing serum calcium and parathyroid hormone (PTH) concentrations after 1 year of treatment. Methods: The study included 20 patients with PHPT who had completed at least 12 months of treatment with cinacalcet (eight patients for refusal of parathyroidectomy, three for surgery not possible due to comorbidities and nine for progressive hypercalcemia prior to surgery). We recorded clinical and biochemical data at baseline, and after 3, 6 and 12 months of treatment. We also monitored adverse events. Cinacalcet was administered in increasing doses until normal serum calcium was reached or side effects preventing a further increase occurred. Results: After 3 months of treatment, serum calcium significantly decreased (11.73 ± 0.85 versus 10.71 ± 1.63 mg/dl, p < 0.001) and serum phosphorus significantly increased (2.41 ± 0.48 versus 2.63 ± 0.70 mg/dl, p = 0.004) while no significant change occurred in PTH (181.91 ± 102.37 versus 195.47 ± 111.71 pg/ml, p = 0.695). No further variation was observed after 6 months compared with 3 months of follow up. However, after 12 months of treatment, there was a significant decrease in PTH concentrations compared with baseline (181.91 ± 102.37 versus 152.47± 70.16 pg/ml, p = 0.028) as well as serum calcium (11.73 ± 0.85 versus 10.20± 0.95 mg/dl, p < 0.001); serum phosphorus significantly increased (2.41 ± 0.48 versus 2.71 ± 0.43 mg/dl, p = 0.01). Normocalcemia (S-Ca < 10.2 mg/dl) was achieved in 55% of patients. The medication was usually well tolerated (83.4%). Most common adverse events were nausea and vomiting, especially at the beginning of therapy. Conclusion: Cinacalcet rapidly reduced serum calcium in patients with PHPT and this reduction remained stable after 1 year of treatment. We also observed a decrease in PTH. Cinacalcet is an effective alternative in nonsurgical

  16. Third-Year Results from the Circumarctic Lakes Observation Network (CALON) Project

    NASA Astrophysics Data System (ADS)

    Hinkel, K. M.; Arp, C. D.; Beck, R. A.; Eisner, W. R.; Frey, K. E.; Grosse, G.; Jones, B. M.; Kim, C.; Lenters, J. D.; Liu, H.; Townsend-Small, A.

    2014-12-01

    Since 2012, 60 lakes in northern Alaska have been instrumented under the auspices of CALON, a project designed to document landscape-scale variability in physical and biogeochemical processes of Arctic lakes in permafrost terrain. The network has ten observation nodes along two latitudinal transects extending from the Arctic Ocean inland some 200 km to the Brooks Range foothills. At each node, a meteorological station is deployed, and six representative lakes of differing area and depth are instrumented and sampled at different intensity levels to collect basic field measurements. In April, sensors measuring water temperature and depth are deployed through the ice in each lake, ice and snow thickness recorded, and water samples are collected. Data are downloaded, lakes re-sampled, and bathymetric surveys are conducted in August. In 2014, the snow cover on inland lakes was thinner than in previous years but thicker on lakes located near the coast. Lake ice was generally thinner near the coast, but the difference diminished inland. Winters (Oct-March) have been progressively warmer over the 3-year period, which partially explains the thinner lake ice that formed in 2013-14. Lakes are typically well-mixed and largely isothermal, with minor thermal stratification occurring in deeper lakes during calm, sunny periods. These regional lake and meteorological data sets, used in conjunction with satellite imagery, supports the wind-driven lake circulation model for the origin of thermokarst lakes. Results of biogeochemical analyses of lake waters generally show notably higher concentrations of cations/anions, chromophoric dissolved organic matter, and chlorophyll-a during April as compared with August. Dissolved methane concentrations are also much higher under ice than in open water during summer, although all lakes are a source of atmospheric methane. Interviews with indigenous elders in Anaktuvuk Pass indicate that mountain lakes are drying up. During the 2014 breakup

  17. ESA SMART-1 mission: review of results and legacy 10 years after launch

    NASA Astrophysics Data System (ADS)

    Foing, Bernard

    2014-05-01

    We review ESA's SMART-1 highlights and legacy 10 years after launch. The SMART-1 mission to the Moon achieved record firsts such as: 1) first Small Mission for Advanced Research and Technology; with spacecraft built and integrated in 2.5 years and launched 3.5 years after mission approval; 2) first mission leaving the Earth orbit using solar power alone with demonstration for future deep space missions such as BepiColombo; 3) most fuel effective mission (60 litres of Xenon) and longest travel (13 month) to the Moon!; 4) first ESA mission reaching the Moon and first European views of lunar poles; 5) first European demonstration of a wide range of new technologies: Li-Ion modular battery, deep-space communications in X- and Ka-bands, and autonomous positioning for navigation; 6) first lunar demonstration of an infrared spectrometer and of a Swept Charge Detector Lunar X-ray fluorescence spectrometer ; 7) first ESA mission with opportunity for lunar science, elemental geochemistry, surface mineralogy mapping, surface geology and precursor studies for exploration; 8) first controlled impact landing on the Moon with real time observations campaign; 9) first mission supporting goals of the ILEWG/COSPAR International Lunar Exploration Working Group in technical and scientific exchange, international collaboration, public and youth engagement; 10) first mission preparing the ground for ESA collaboration in Chandrayaan-1, Chang'E1-2-3 and near-future landers, sample return and human lunar missions. The SMART-1 technology legacy is applicable to geostationary satellites and deep space missions using solar electric propulsion. The SMART-1 archive observations have been used to support scientific research and prepare subsequent lunar missions and exploration. Most recent SMART-1 results are relevant to topics on: 1) the study of properties of the lunar dust, 2) impact craters and ejecta, 3) the study of illumination, 4) observations and science from the Moon, 5) support to

  18. Class V lesions restored with four different tooth-colored materials--3-year results.

    PubMed

    Folwaczny, M; Loher, C; Mehl, A; Kunzelmann, K H; Hickel, R

    2001-03-01

    The aim of this study was to compare the treatment results using four different types of tooth colored materials for restoring class V lesions. A total of 197 class V restorations (n = 197) were placed by one dentist in 37 patients on incisors, canines and premolars. The fillings were placed due to different indications: erosion/non-carious cervical defects (n = 69), primary carious lesions (n = 57), and for replacing defective existing fillings (n = 71). The teeth were assigned on a random basis to four groups for restoration with either a composite (group 1: n = 36; Tetric, Vivadent), or a polyacid-modified resin composite (group 2: n = 79; Dyract, Dentsply), or one of two different resin-modified glass ionomer cements (group 3: n = 51, Fuji II LC,GC; group 4: n = 31, Photac-Fil, Espe). The restorations were evaluated by a single-blind design, according to a modified USPHS system 36 months following placement. Statistical analysis was completed with the Pearson Chi-square test for comparing the results of the four groups (P < 0.05). Additionally, the survival rates were analyzed with the Kaplan-Meier estimator and the Log-rank test (P < 0.05). The Alpha ratings were as follows (Tetric/Dyract/Fuji II LC/Photac Fil): shade match (86%/77%/58%/40%), surface texture (81%/83%/16%/9%), marginal integrity (enamel) (73%/67%/61%/61%), marginal integrity (dentin) (86%/70%/55%/61%), marginal discoloration (enamel) (59%/44%/58%/52%), marginal discoloration (dentin) (82%/84%/71%/48%), anatomic contours (91%/83%/39%/35%). One Tetric restoration, five Dyract restorations, two Fuji II LC restorations and three Photac restorations were dislodged within the study period. The retention of the restorations showed no significant difference among the four materials. However, the clinical performance of the restorations retained over the 3-year period showed distinct differences for the four materials. The best clinical performance was observed for the resin composite, whereas the

  19. Results of the seven-year prospective study of stroke patients.

    PubMed

    Scmidt, E V; Smirnov, V E; Ryabova, V S

    1988-08-01

    Using the registry method, 1,538 stroke patients were detected in one district of Moscow between January 1, 1972, and December 31, 1974. Of the 965 patients who survived the acute stage of stroke (the first 3 weeks after onset), 941 (505 women and 436 men) were followed for the next 7 years. We analyzed incidence and types of recurrent strokes. During this 7-year follow-up, we recorded 32.1% of the patients as having recurrent strokes, most of which developed in the first 3 years and especially during the first year after the index stroke. The majority of recurrent strokes were of the same type as the index stroke and were localized in the same area of the brain. The cumulative mortality rates for the initial 1,538 patients were 37.3% dead by 3 weeks, 63.6% dead by 3 years, 72.1% dead by 5 years, and 76.5% dead by 7 years. In the first 3 months (excluding the first 3 weeks), most patients who died died of pulmonary thromboembolism. The mortality rate from recurrent strokes and pneumonia was higher than that from cardiovascular mortality. Transient ischemic attacks occurred in 49.5% of all patients and myocardial infarction in 16.4%. Functional prognosis was determined mainly by age, motor function, and concomitant diseases. After 1 year, 68.2% of the surviving patients were fully independent, while 81% of those surviving 7 years had reached this level. A significant number of patients were capable of returning to their previous work.

  20. Results from the Astronomy Diagnostic Test: 3 Years at MiraCosta College

    NASA Astrophysics Data System (ADS)

    Sirbaugh French, Rica

    2007-12-01

    The Astronomy Diagnostic Test 2.0 (ADT) was administered to 26 sections of ASTR 101 at MiraCosta College (MCC) from fall 2004 through summer 2007. MiraCosta is a two-year community college located in Oceanside, CA, USA (roughly 40 miles north of San Diego) with an enrollment of approximately 11,000 students. ASTR 101 is MiraCosta's introductory astronomy survey course for non-science majors and has no math prerequisite. Class sizes ranged from 10 to 38 students. Comparison with the ADT National Project results indicates similar pre- and post-course averages: 31.8% (MCC) vs. 32.4% (National) for pre-course tests and 49.3% (MCC) vs. 47.3% (National) for post-course tests. The sample sizes are 709 and 530 students for the pre- and post-tests, respectively. The normalized gain for the entire data set is 0.256 and the effect size (ES) is 1.04, meaning that approximately 85% of the post-test scores are above the average of the pre-test scores. Previous studies have shown the ADT to be a reliable indicator of pre-course misconceptions while post-course scores are useful for comparing modes of instruction and assessing student learning on a limited number of concepts. Additional analyses of the MCC data probe for trends with variables such as gender, class size, and implementation of materials designed for a more "learner-centered” approach (such as Lecture Tutorials, Ranking Tasks, and Think-Pair-Share questions), as well as gains for a particular subset of concepts.

  1. Results of many-year subsatellite measurements of current fine structure in northeastern Black Sea

    NASA Astrophysics Data System (ADS)

    Lavrova, Olga; Krayushkin, Evgeny; Kalashnikova, Nina

    Results of subsatellite measurements of coastal currents in the shelf zone of northeastern Black Sea are presented. The measurements have been performed every year since 2006 in June and September-October months near the Gelendzhik Bay. The main instruments used are Acoustic Doppler Current Profilers (ADCP) and CTD probes. Ground and ship measurements were conducted simultaneously with satellite imaging in microwave (ASAR Envisat, ERS-2, RADARSAT-2, TerraSAR-X), visible and infrared (OLI Landsat-8, ETM+ Landsat-7, TM Landsat-5, MODIS Terra/Aqua, AVHRR NOAA) ranges. The investigations performed revealed spatial, depth and temporal variability of current direction and velocity in the shelf zone. Multiple instances of counter-currents opposing to the Ring Current were registered. In our view, they are associated with a passage of small-scale anticyclonic eddies across the region of interest. The 3D structure of the eddies in the upper quasi-uniform layer was analyzed based on ADCP data. The use of high resolution (3 m) SAR data in combination with ADCP measurements at the resolution of 0.5 m allowed us to detect a number of internal wave trains. Form ADCP and thermistors records, their amplitudes were estimated to reach 5-8 m. Joint analysis of satellite SAR and subsatellite data gave an assessment of their typical wavelength at 90-100 m. Generation mechanisms of these internal waves are suggested. Another phenomenon of interest observed in the region of the measurements is surface manifestations of ring waves near localized natural and anthropogenic generation sources. Such ring waves are most frequently found in the anchor area for ships, whose oscillations can be the source of their generation. The work was in part supported by the Russian Foundation for Basic Research (projects #14-05-00520-а, and 13-07-12017-ofi_m). SAR data from RADARSAT-2 and TerraSAR-X were obtained under SOAR RADARSAT-2/TerraSAR-X Project #5074.

  2. Prospective evaluation of an in-center daily hemodialysis program: results of two years of treatment.

    PubMed

    André, Mauro B; Rembold, Simone M; Pereira, Claudia M; Lugon, Jocemir R

    2002-01-01

    Short duration daily hemodialysis (DHD) emerges as a well-tolerated alternative to standard hemodialysis (SHD). In this prospective study 5 patients in SHD were recruited to participate in an in-center DHD program. The SHD consisted of 3 sessions of 4 h each per week. Nonproportional mixture machines without an ultrafiltration control device and low flow dialyzers were used. For DHD, dialysis equipment and procedures were kept the same. Dialysis sessions, however, began at 6 p.m. (from Monday to Saturday) and lasted 2 h. Data from the last 6 months on SHD of the same patients were compared with the ones from each semester on DHD. Bone biopsy was performed at start and at the end of the 2-year study period. Hypotensive episodes, hypertensive crisis, cramps and headaches became 7-10 times less frequent in daily dialysis. A significant fractional increase ( approximately 12%) was seen in mean values for hematocrit. Predialysis urea levels as well as predialysis creatinine levels declined significantly. Also lower during the daily dialysis period were the mean values for both phosphorus and CaxP product. Significant increases were found in serum bicarbonate, albumin and in dry weight. The frequency of mean blood pressure >/=110 mm Hg on arrival for dialysis was significantly lower in every semester on daily hemodialysis. A significant twofold improvement in quality of life scoring was observed. Finally, daily hemodialysis also seemed to be beneficial to low turnover bone disease and bone aluminum deposition. These beneficial effects occurred despite of an increase in the frequency of missing days. Results from the present study which prospectively addressed the role of in-center short daily hemodialysis in the management of ESRD are encouraging.

  3. Vehicle technologies program Government Performance and Results Act (GPA) report for fiscal year 2012

    SciTech Connect

    Ward, J.; Stephens, T. S.; Birky, A. K.

    2012-08-10

    The U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy has defined milestones for its Vehicle Technologies Program (VTP). This report provides estimates of the benefits that would accrue from achieving these milestones relative to a base case that represents a future in which there is no VTP-supported vehicle technology development. Improvements in the fuel economy and reductions in the cost of light- and heavy-duty vehicles were estimated by using Argonne National Laboratory's Autonomie powertrain simulation software and doing some additional analysis. Argonne also estimated the fraction of the fuel economy improvements that were attributable to VTP-supported development in four 'subsystem' technology areas: batteries and electric drives, advanced combustion engines, fuels and lubricants, and materials (i.e., reducing vehicle mass, called 'lightweighting'). Oak Ridge National Laboratory's MA{sup 3}T (Market Acceptance of Advanced Automotive Technologies) tool was used to project the market penetration of light-duty vehicles, and TA Engineering's TRUCK tool was used to project the penetrations of medium- and heavy-duty trucks. Argonne's VISION transportation energy accounting model was used to estimate total fuel savings, reductions in primary energy consumption, and reductions in greenhouse gas emissions that would result from achieving VTP milestones. These projections indicate that by 2030, the on-road fuel economy of both light- and heavy-duty vehicles would improve by more than 20%, and that this positive impact would be accompanied by a reduction in oil consumption of nearly 2 million barrels per day and a reduction in greenhouse gas emissions of more than 300 million metric tons of CO{sub 2} equivalent per year. These benefits would have a significant economic value in the U.S. transportation sector and reduce its dependency on oil and its vulnerability to oil price shocks.

  4. Utilizing First-Year Curricula Linkage to Improve In-Major Persistence to Graduation: Results from a Four-Year Longitudinal Study, Fall 2000-Spring 2004

    ERIC Educational Resources Information Center

    Lifton, Donald; Cohen, Alan; Schlesinger, Warren

    2008-01-01

    Academic departments have expanded the typical persistence agenda of First-Year Seminars to use them specifically as tools for in-major retention. This article reports the empirical results of a four-year longitudinal study assessing the successful efforts to improve the persistence-to-graduation-within-major of business students. The pedagogy can…

  5. Preparing students in two-year colleges for geoscience degrees and careers: Workshop results

    NASA Astrophysics Data System (ADS)

    Macdonald, H.; Baer, E. M.; Blodgett, R. H.; Hodder, J.

    2012-12-01

    Building a strong and diverse geoscience workforce is a critical national challenge. Two-year colleges (2YCs) play an important role in increasing both the number and diversity of geoscience graduates. A workshop on Preparing Students from Two-year Colleges for Geoscience Degrees and Careers was held in Tacoma, WA in July 2012 to discuss the successes and challenges of programs, strategies, and activities that support career preparation of 2YC students for geoscience careers, either as geotechnical graduates or as geoscience majors at four-year colleges and universities, and to make recommendations for future efforts. At the workshop several successful partnerships between employers and two-year colleges as well as between two-year colleges and four-year institutions were discussed as potential models that could be replicated with adaptations for local employment needs. Participants shared successful techniques for supporting 2YC students in their career path such as internships, early opportunities for participating in research, joint fieldtrips with transfer institutions, and supportive curriculum alignment between two and four-year institutions. Professional organizations have much to offer including information about career options, networking opportunities, and more. Participants discussed strategies for supporting geoscience workforce development at 2YCs such as making connections between 2YCs and local employers, identifying geoscience students at 2YCs who are planning to transfer and building relationships with 4YCs, establishing internship programs, supporting student geoscience clubs, and developing a repository of geoscience employment information targeted to 2YC students. Participants recognized significant barriers to incorporating career training and information into the geoscience curriculum at two-year colleges. These barriers include a predominance of non-geoscience students in classes, lack of support or rewards for improving or increasing the

  6. Second-Year Results from the Circumarctic Lakes Observation Network (CALON) Project

    NASA Astrophysics Data System (ADS)

    Hinkel, K. M.; Arp, C. D.; Beck, R. A.; Eisner, W. R.; Frey, K. E.; Gaglioti, B.; Grosse, G.; Jones, B. M.; Kim, C.; Lenters, J. D.; Liu, H.; Townsend-Small, A.

    2013-12-01

    temperatures in small shallow lakes and more southern latitudes. Most lakes are well-mixed and largely isothermal, with short periods of thermal stratification occurring in deeper lakes during calm, sunny periods. Over the ice-free season, the majority of the available energy from net radiation goes into evaporation, followed by sensible heat flux and warming of bottom sediments. Thermal bands of MODIS and Landsat imagery were fused using a spatio-temporal cokriging method to generate daily surface temperature estimates at Landsat spatial resolution. The close correspondence between satellite-derived and in situ measured near-surface lake temperature suggests that this approach yields viable results. Biogeochemical and inorganic geochemical constituents measured include dissolved greenhouse gas concentrations (CO2, CH4, and N2O), inorganic N, DON and DOC, alkalinity, chlorophyll-a, major ions, and CDOM. The greatest difference in the dissolved CH4:CO2 ratio in summer was longitudinal, with several lakes in western Alaskan Arctic exhibiting CH4 concentrations hundreds of times more supersaturated than air. Stable isotope analyses of CH4 (δ13C and δ2H) show that several of these lakes have natural gas methane sources. Methane concentrations under ice (April) were several thousand times higher than in open-water conditions (August). Data collected during this 4-year project are archived at A-CADIS.

  7. [3-year results of clinical and immunological monitoring of patients with multiple sclerosis treated by copaxone].

    PubMed

    Orlova, Iu Iu; Alifirova, V M; Cherdyntseva, N V; Zagrebina, I A; Bychkova, I V

    2005-01-01

    Tipe 1 T-helper cells are of importance in development of multiple sclerosis (MS). Copaxone (TEVA, Israel) is one of the preventive drugs, which modifies T-helpers activity. Thirty-three patients with MS were treated by copaxone for 2 years and 13 patients--for 3 years. Clinical and immunological parameters were examined: amount of CD3+, CD4+, CD8+, CD16+, CD22+, CD95+, CD25+ lymphocytes, HLA-D+ cells, IgG, IgA, IgM and phagocytosis. During the treatment course, mean rate of relapses decreased from the pretreatment value from 1.26 +/- 0.11 to 0.59 +/- 0.11 in the first year and 0.28 +/- 0.07 in the second one. After 3 years no relapses were observed in 13 patients. Relapse rate was the highest in the first 3-6 months. But after 3 months there was an increase of CD22+ cells that persisted for all the period of the study. After a year of the treatment, a level of IgM, IgG, IgA and CD95+ cells has raised significantly, with decreasing of a number of CD4+ and CD8+ cells. The authors suggest that immunological shift is related to mechanism of copaxone action determining its positive effect i.e. reducing of frequency of MS relapses.

  8. Comparing gender awareness in Dutch and Swedish first-year medical students - results from a questionaire

    PubMed Central

    2012-01-01

    Background To ascertain good and appropriate healthcare for both women and men implementation of gender perspectives in medical education is needed. For a successful implementation, knowledge about students' attitudes and beliefs about men, women, and gender is crucial. The aim of this study was to compare attitudes to gender and gender stereotyping among Dutch and Swedish male and female medical students. Methods In this cross-sectional study, we measured the attitudes and assumptions about gender among 1096 first year medical students (616 Dutch and 480 Swedish) with the validated Nijmegen Gender Awareness in Medicine Scale (N-GAMS). The response rate was 94% in the Netherlands and 93% in Sweden. Univariate analysis of variance (ANOVA) was used to compare the scores between Dutch and Swedish male and female students. Linear regressions were used to analyze the importance of the background variables. Results There were significant differences in attitudes to gender between Dutch and Swedish students. The Swedish students expressed less stereotypical thinking about patients and doctors and the Dutch were more sensitive to gender differences. The students' sex mattered for gender stereotyping, with male students in both countries agreeing more with stereotypical statements. Students' age, father's birth country and mother's education level had some impact on the outcome. Conclusions There are differences between cultures as well as between men and women in gender awareness that need to be considered when implementing gender in medical education. This study suggests that to arouse the students' interest in gender issues and make them aware of the significance of gender in medical work, the examples used in discussions need to be relevant and challenging in the context of the specific country. Due to different levels of knowledge and different attitudes within the student population it is important to create a climate for dialogue where students feel permitted to

  9. AMIE SMART-1: review of results and legacy 10 years after launch

    NASA Astrophysics Data System (ADS)

    Josset, Jean-Luc; Souchon, Audrey; Josset, Marie; Foing, Bernard

    2014-05-01

    The Advanced Moon micro-Imager Experiment (AMIE) camera was launched in September 2003 onboard the ESA SMART-1 spacecraft. We review the technical characteristics, scientific objectives and results of the instrument, 10 years after its launch. The AMIE camera is an ultra-compact imaging system that includes a tele-objective with a 5.3° x 5.3° field of view and an imaging sensor of 1024 x 1024 pixels. It is dedicated to spectral imaging with three spectral filters (750, 915 and 960 nm filters), photometric measurements (filter free CCD area), and Laser-link experiment (laser filter at 847 nm). The AMIE camera was designed to acquire high-resolution images of the lunar surface, in white light and for specific spectral bands, under a number of different viewing conditions and geometries. Specifically, its main scientific objectives included: (i) imaging of high latitude regions in the southern hemisphere, in particular the South Pole Aitken basin and the permanently shadowed regions close to the South Pole; (ii) determination of the photometric properties of the lunar surface from observations at different phase angles (physical properties of the regolith); (iii) multi-band imaging for constraining the chemical and mineral composition of the surface; (iv) detection and characterisation of lunar non-mare volcanic units; (v) study of lithological variations from impact craters and implications for crustal heterogeneity. The study of AMIE images enhanced the knowledge of the lunar surface, in particular regarding photometric modelling and surface physical properties of localized lunar areas and geological units. References: http://scholar.google.nl/scholar?q=smart-1+amie We acknowledge ESA, member states, industry and institutes for their contribution, and the members of the AMIE Team: J.-L. Josset, P. Plancke, Y. Langevin, P. Cerroni, M. C. De Sanctis, P. Pinet, S. Chevrel, S. Beauvivre, B.A. Hofmann, M. Josset, D. Koschny, M. Almeida, K. Muinonen, J. Piironen, M. A

  10. [Stabilizing effect of orthokeratology lenses (ten-year follow-up results)].

    PubMed

    Tarutta, E P; Verzhanskaya, T Yu

    2017-01-01

    The global prevalence of myopia in adults varies between 20-50% in Europe and the US and 60-90% in Asian countries. According to WHO, myopia is one of the five leading causes of blindness and low vision in the world. Prevention or deceleration of myopia progression is an important public health problem. In recent years, orthokeratology (ortho-k) contact lenses worn at night have been found effective in slowing down the progression of myopia, however, the follow-up period in related studies is no longer than five years.

  11. Remotely Operated Vehicles under sea ice - Experiences and results from five years of polar operations

    NASA Astrophysics Data System (ADS)

    Katlein, Christian; Arndt, Stefanie; Lange, Benjamin; Belter, Hans Jakob; Schiller, Martin; Nicolaus, Marcel

    2016-04-01

    The availability of advanced robotic technologies to the Earth Science community has largely increased in the last decade. Remotely operated vehicles (ROV) enable spatially extensive scientific investigations underneath the sea ice of the polar oceans, covering a larger range and longer diving times than divers with significantly lower risks. Here we present our experiences and scientific results acquired from ROV operations during the last five years in the Arctic and Antarctic sea ice region. Working under the sea ice means to have all obstacles and investigated objects above the vehicle, and thus changes several paradigms of ROV operations as compared to blue water applications. Observations of downwelling spectral irradiance and radiance allow a characterization of the optical properties of sea ice and the spatial variability of the energy partitioning across the atmosphere-ice-ocean boundary. Our results show that the decreasing thickness and age of the sea ice have led to a significant increase in light transmission during summer over the last three decades. Spatially extensive measurements from ROV surveys generally provide more information on the light field variability than single spot measurements. The large number of sampled ice conditions during five cruises with the German research icebreaker RV Polarstern allows for the investigations of the seasonal evolution of light transmittance. Both, measurements of hyperspectral light transmittance through sea ice, as well as classification of upward-looking camera images were used to investigate the spatial distribution of ice-algal biomass. Buoyant ice-algal aggregates were found to be positioned in the stretches of level ice, rather than pressure ridges due to a physical interaction of aggregate-buoyancy and under-ice currents. Synchronous measurements of sea ice thickness by upward looking sonar provides crucial additional information to put light-transmittance and biological observations into context

  12. The Literacy Programs of Save the Children: Results from the 2008-09 School Year

    ERIC Educational Resources Information Center

    Palmiter, Andrea S.; Arcaira, Erikson R.; White, Richard N.; Reisner, Elizabeth R.

    2009-01-01

    Since the 2003-04 school year, Save the Children, U.S. Programs, has supported programming designed to improve reading skills among struggling students in rural areas. The literacy program includes both afterschool and in-school interventions with small groups of children. These are implemented by well-trained paraprofessionals and are designed to…

  13. FINE ROOT TURNOVER IN PONDEROSA PINE STANDS OF DIFFERENT AGES: FIRST-YEAR RESULTS

    EPA Science Inventory

    Root minirhizotron tubs were installed in two ponderosa pine (Pinus ponderosa Laws.) Stands of different ages to examine patterns of root growth and death. The old-growth site (OS) consists of a mixture of old (>250 years) and young trees (ca.45 yrs)< and is located near clamp S...

  14. [100 years tendovaginitis stenosans de Quervain--review of the literature and personal results].

    PubMed

    Wetterkamp, D; Rieger, H; Brug, E

    1997-07-01

    One hundred years ago, Fritz de Quervain first described the surgical treatment of tendovaginitis of the first dorsal compartment. Since then, various ways of treatment have been pointed out. In a series of 72 patients treated surgically, 82% recovered completely. Postoperative complaints included irritations of the superficial branch of the radial nerve.

  15. Hispanic Students and the Gates Millennium Scholarship Program: Promising Results Extending to the Third College Year

    ERIC Educational Resources Information Center

    Oseguera, Leticia; Denson, Nida; Hurtado, Sylvia

    2009-01-01

    Financing college is increasingly difficult for many college students and it can be especially difficult for low-income students. Using data from the Gates Millennium Scholarship Program, this study provides a portrait of the 1st and 3rd year experiences of a sample of both high achieving Hispanic scholarship recipients and non-recipients.…

  16. Project ALERT Accomplishments by Objectives. Final Performance Report. Three-Year Results.

    ERIC Educational Resources Information Center

    Wayne State Univ., Detroit, MI. Coll. of Education.

    Project ALERT (Adult Literacy Enhanced & Redefined through Training) was a 3-year effort to develop and deploy a number of innovative approaches to delivering workplace literacy programs to business partners, including manufacturers and unions. The project designed, developed, and implemented workplace literacy programs tailored to the…

  17. The Status of Chemistry in Two-Year Colleges: Results from a Survey of Chemistry Departments.

    ERIC Educational Resources Information Center

    Ryan, Mary Ann; Wesemann, Jodi L.; Boese, Janet M.; Neuschatz, Michael

    In the fall of 2001, the American Chemical Society (ACS) conducted a survey of two-year college chemistry departments to obtain basic data on chemistry faculty and chemistry courses taught at college. A questionnaire sent to appropriate representatives (department chairs, program heads, or deans) from 1195 campuses generated a 77% response rate.…

  18. Jobs for America's Graduates 30th Anniversary Annual Report: Celebrating Thirty Years of Achieving Extraordinary Results!

    ERIC Educational Resources Information Center

    Jobs for America's Graduates, Inc., 2012

    2012-01-01

    Jobs for America's Graduates (JAG) is a national not-for-profit organization with a 30-year tested and proven model to cost effectively prevent school dropout among young people facing challenges of staying in school through graduation, pursuing postsecondary education and/or securing quality entry-level jobs. JAG stakeholders passionately believe…

  19. UAHuntsville and NASA-MSFC Heliophysics REU: Year One Strategy and Results

    NASA Astrophysics Data System (ADS)

    Farid, S.; Heerikhuisen, J.; Winebarger, A. R.

    2012-12-01

    Scientists from the University of Alabama in Huntsville and NASA Marshall Space Fight Center (MSFC) received a 3-year National Science Foundation (NSF) award to create a unique Heliophysics Research Experience for Undergraduates (REU). For 10 weeks, 10 undergraduate students engaged in cutting edge heliophysics research with NASA or UAHuntsville astrophysicists specializing in research from the solar interior to the heliopause. Research projects included theory, modeling, computer simulations, data analysis and instrument design. The primary objectives of this REU are to 1.) increase minority participation in science, technology and mathematics (STEM) fields in general, and heliophysics in particular, and 2.) decrease the STEM attrition rate in first and second year students. This REU is unique because of our focus on recruiting talented students that may not have otherwise participated in an REU. In addition to the usual criteria of most REUs, consideration of need was also given to those students who were sophomores, students with little or no previous research experience, those from small or non-PhD granting institutions, students with less than average GPA, minorities, women, etc. In this poster, we review the effectiveness of the first year strategy. We evaluate the recruitment and application process, mentor placement, living and working arrangements, introductory tutorials, and merit of final research projects. We present modifications for next year's effort, and make suggestions to similar REU programs.

  20. [Smoking and mortality in Swiss physicians: results of an 18-year survey].

    PubMed

    Gsell, O; Abelin, T; Wieltschnig, E

    1979-03-01

    A prospective mortality study of tobacco smoking of Swiss physicians is reported over a period of 18 years (1955-1973). The mortality rate increases with the intensity of the daily smoking quantity, going till to the double of non-smokers. This elevation is not seen in late smokers. Contrary to the habits of English doctors, who smoke mostly cigarettes, in Switzerland the death rates of cigars (mostly Stumpen) and pipe smokers are as much elevated as for cigarette smokers. In intensive smokers the mortality reached for all 3 the same rate (2,4-2,6). Under the various causes of death lung cancer was only seen in smokers (92,5% intensive smokers). Heart infarctions death has in smokers the highest rate in the age of 35-54 years, going back till 75 years where the death rate is nearly the same as in non-smokers. The passover in mortality of the intensive smokers in full activity of life is documentated by the statistic of Swiss Doctors. Therefore it is a positive factor that in the last 18 years the number of cigarette-smokers in physicians declined from 37% to 21% and the number of past-smokers has gone up from 17 to 38%, but the number of only cigars and pipesmokers is always the same.

  1. Idaho Statewide Implementation of Reading Renaissance[R]: Summary of First Year's Results. Monograph.

    ERIC Educational Resources Information Center

    School Renaissance Inst., Inc., Madison, WI.

    In 1998, as part of a major 3-year Reading Initiative, the Albertson Foundation provided $24.5 million to improve the reading performance of all Idaho elementary, middle, and junior high students. The reading components of School Renaissance (SR), a comprehensive school improvement program, include Accelerated Reader (AR) learning information…

  2. Cryogenic Storage of Cereal Grains: Results from a 20 Year Experiment

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This paper compares the viability of small grains stored under conventional (-18oC) or cryogenic conditions (vapor above liquid nitrogen(LN)) for 22 to 25 years at the National Center for Genetic Resources Preservation. Several accessions of different small grains crops were split in 1984-1987, stor...

  3. Effects of supervised daily dental plaque removal by children: first-year results.

    PubMed

    Horowitz, A M; Suomi, J D; Peterson, J K; Voglesong, R H; Mathews, B L

    1976-01-01

    In September 1973, a three-year school-based study was initiated in East Hampton, Connecticut, a rural nonfluoridated community. The purpose of the study is to determine the effect on dental decay, gingival inflammation and oral hygiene of removing dental plaque through supervised daily toothbrushing and flossing in school during a three-year period. To establish baseline data, three indexes were used: the DHC Index to evaluate gingivitis; the DMF Surface Index to quantify dental caries and the PHP Index to measure dental plaque. The examinations for dental caries, including radiographs, are scheduled annually in September, whereas the plaque and gingival examinations are done biannually, in September and June. After the baseline examinations the 481 children were blocked according to grade and sex and then were randomly assigned to either a treatment group or to a control group. In November, the treatment group was provided 10 sessions of instruction in plaque removal. For the remainder of the year (six months) they practiced daily plaque removal, supervised by a dental hygienist and a nurse. The control group was not instructed in oral hygiene procedures. In the treatment group, mean plaque and gingival scores at the June (first follow-up) examination were 14 percent and 29 percent lower, respectively, than at baseline. No change was seen in the control group. At the second follow-up examination in September (after summer vacation), the same indexes were nearly at baseline levels in the treatment group. There was no treatment effect on dental caries increments after one year of study. Considering the nature of the treatment regimen and the few treatments during the first year of the study, it is not surprising that there were no caries-preventive benefits demonstrated among children in the treatment group after one year. The total number of the plaque removal sessions will be greater during the second year of the study. Therefore, the possibility of detecting a

  4. Epilation for Minor Trachomatous Trichiasis: Four-Year Results of a Randomised Controlled Trial

    PubMed Central

    Habtamu, Esmael; Rajak, Saul N.; Tadesse, Zerihun; Wondie, Tariku; Zerihun, Mulat; Guadie, Birhan; Gebre, Teshome; Kello, Amir Bedri; Callahan, Kelly; Mabey, David C. W.; Khaw, Peng T.; Gilbert, Clare E.; Weiss, Helen A.; Emerson, Paul M.; Burton, Matthew J.

    2015-01-01

    Background Trachomatous trichiasis (TT) needs to be managed to reduce the risk of vision loss. The long-term impact of epilation (a common traditional practice of repeated plucking of lashes touching the eye) in preventing visual impairment and corneal opacity from TT is unknown. We conducted a randomized controlled trial of epilation versus surgery for the management of minor TT (fewer than six lashes touching the eye) in Ethiopia. Here we report the four-year outcome and the effect on vision and corneal opacity. Methodology/ Principal Findings 1300 individuals with minor TT were recruited and randomly assigned to quality trichiasis surgery or repeated epilation using high quality epilation forceps by a trained person with good near vision. Participants were examined six-monthly for two-years, and then at four-years after randomisation. At two-years all epilation arm participants were offered free surgery. At four-years 1151 (88.5%) were re-examined: 572 (88%) and 579 (89%) from epilation and surgery arms, respectively. At that time, 21.1% of the surgery arm participants had recurrent TT; 189/572 (33%) of the epilation arm had received surgery, while 383 (67%) declined surgery and had continued epilating (“epilation-only”). Among the epilation-only group, 207 (54.1%) fully controlled their TT, 166 (43.3%) had minor TT and 10 (2.6%) had major TT (>5 lashes). There were no differences between participants in the epilation-only, epilation-to-surgery and surgery arm participants in changes in visual acuity and corneal opacity between baseline and four-years. Conclusions/ Significance Most minor TT participants randomised to the epilation arm continued epilating and controlled their TT. Change in vision and corneal opacity was comparable between surgery and epilation-only participants. This suggests that good quality epilation with regular follow-up is a reasonable second-line alternative to surgery for minor TT for individuals who either decline surgery or do not

  5. SOHO celebrates its first year in space with new results on the solar wind

    NASA Astrophysics Data System (ADS)

    1996-12-01

    hot atmosphere and its emissions into the solar system; But to fulfil its high promise, SOHO must continue operating at least until the maximum of sunspot activity around the year 2000". Joining in SOHO's anniversary greetings is Eigil Friis Christensen, a solar-terrestrial physicist at the Danish Meteorological Institute. He has played a prominent role in tracing the effects of solar variations on the terrestrial climate. "SOHO is now vital for understanding the Earth's environment", Friis Christensen says. "I am convinced that long-term changes in the strength and variability of the solar wind alter the climate, but no one knows why those changes occur. In the years ahead, as it follows the dramatic events leading from the sunspot minimum to the sunspot maximum, SOHO should reveal the processes inside the Sun that influence the character of the solar wind. If so, it will open a new chapter in solar-terrestrial climatology". Other highlights from SOHO's programme Previous ESA Information Notes (07-96 and 16-96) and photo releases have sketched SOHO's results on the solar wind and coronal mass ejections, mentioned here in connection with the LASCO, UVCS, CELIAS and SWAN instruments. The particle detectors COSTEP and ERNE have registered high-energy electrons and hydrogen and helium nuclei flung out by violent eruptions in the Sun. These particle events will become commoner as the sunspot count increases and the Sun becomes stormier. The EIT imager's many observations of the solar atmosphere by extreme ultraviolet rays have included spectacular images of tangled magnetic fields creating intense disturbances even at times when the Sun appeared extremely calm to visible-light telescopes on the ground. SOHO's ultraviolet spectrographs SUMER and CDS analyse the never-ending explosive events in the atmosphere in more detail. This is part of a concerted effort to fulfil another of SOHO's key tasks, in explaining how the Sun's atmosphere attains temperatures of millions of

  6. First Year Results from the Circumarctic Lakes Observation Network (CALON) Project

    NASA Astrophysics Data System (ADS)

    Hinkel, K. M.; Arp, C. D.; Frey, K. E.; Lenters, J. D.; Beck, R. A.; Eisner, W. R.; Gaglioti, B.; Grosse, G.; Jones, B. M.; Kim, C.; Liu, H.; Townsend-Small, A.

    2012-12-01

    -lake variability related to snow depth. Rapid warming follows ice-off, with water temperature responding synchronously to synoptic weather variations across the area. Regionally, ice-off occurs 2-4 weeks later on lakes near the coast, but with high inter-lake variability related to lake depth and area. Inland lakes are warmer in mid-summer than those near the coast, reflecting the regional climate gradient and the maritime effect. All lakes are well-mixed and largely isothermal, with some thermal stratification occurring during calm, sunny periods in deeper lakes. This project also involves measurement of carbon and nutrient dynamics and inorganic geochemistry of the lakes. Preliminary data indicate that brown colored lakes have greater dissolved methane concentrations under ice in winter than clear-water lakes, which is promising for remote sensing applications. Through a collaborative effort between the USGS-Alaska Science Center, the BLM Arctic Field Office, the NSF and other partners, we have established the Teshekpuk Lake Observatory as part of the CALON project in order to assess the past, present, and future response of Teshekpuk Lake ecosystem to environmental stressors and change. All data resulting from this 4-year project will be stored at CADIS and a specially designed web portal, and is currently accessible through the CALON web page at https://sites.google.com/a/giesn.com/nsf-calon/.

  7. Five-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Data Processing, Sky Maps, and Basic Results

    NASA Technical Reports Server (NTRS)

    Weiland, J.L.; Hill, R.S.; Odegard, 3.; Larson, D.; Bennett, C.L.; Dunkley, J.; Jarosik, N.; Page, L.; Spergel, D.N.; Halpern, M.; Meyer, S.S.; Tucker, G.S.; Wright, E.L.

    2008-01-01

    The Wilkinson Microwave Anisotropy Probe (WMAP) is a Medium-Class Explorer (MIDEX) satellite aimed at elucidating cosmology through full-sky observations of the cosmic microwave background (CMB). The WMAP full-sky maps of the temperature and polarization anisotropy in five frequency bands provide our most accurate view to date of conditions in the early universe. The multi-frequency data facilitate the separation of the CMB signal from foreground emission arising both from our Galaxy and from extragalactic sources. The CMB angular power spectrum derived from these maps exhibits a highly coherent acoustic peak structure which makes it possible to extract a wealth of information about the composition and history of the universe. as well as the processes that seeded the fluctuations. WMAP data have played a key role in establishing ACDM as the new standard model of cosmology (Bennett et al. 2003: Spergel et al. 2003; Hinshaw et al. 2007: Spergel et al. 2007): a flat universe dominated by dark energy, supplemented by dark matter and atoms with density fluctuations seeded by a Gaussian, adiabatic, nearly scale invariant process. The basic properties of this universe are determined by five numbers: the density of matter, the density of atoms. the age of the universe (or equivalently, the Hubble constant today), the amplitude of the initial fluctuations, and their scale dependence. By accurately measuring the first few peaks in the angular power spectrum, WMAP data have enabled the following accomplishments: Showing the dark matter must be non-baryonic and interact only weakly with atoms and radiation. The WMAP measurement of the dark matter density puts important constraints on supersymmetric dark matter models and on the properties of other dark matter candidates. With five years of data and a better determination of our beam response, this measurement has been significantly improved. Precise determination of the density of atoms in the universe. The agreement between

  8. Pattern of trauma resulting from motorcycle accidents in Nigerians: a two-year prospective study.

    PubMed

    Odelowo, E O

    1994-06-01

    A two-year prospective study of injuries sustained from motor-cycle accidents (MCA) was conducted at the University of Ilorin Teaching Hospital, Ilorin, Nigeria, in 1983 and 1984 after repeal of the national mandatory helmet law. MCA patients constituted 10.3% of 715 road traffic accident (RTA) patients and also presented a 5.7:1 male preponderance. Peak age was 18 to 30 years. Nearly 75% sustained lower extremity, chest and cranioencephalic injuries. Non-operative management sufficed in 34 patients (45.9%) while 30 (40.5%) and 10 (13.5%) require operations respectively. Eighteen (24.3%) and 17 (23.0%) patients required local/spinal and general anesthesia respectively. Mortality was 6.8% (5 patients). This analysis of MCA injuries provides objective basis for current comparison with what obtains in jurisdictions with/without mandatory helmet law and future comparison when the law is re-enacted in our state.

  9. Efficacy of risedronate in men with primary and secondary osteoporosis: results of a 1-year study.

    PubMed

    Ringe, J D; Faber, H; Farahmand, P; Dorst, A

    2006-03-01

    Osteoporosis is prevalent in men with an estimated one in eight men older than 50 years suffering from osteoporotic fracture, and a higher mortality rate after fracture among men compared with women. There are few approved therapies for osteoporosis in men. This observational study assesses the efficacy and safety of risedronate in the treatment of men with primary and secondary osteoporosis. A single-center, open label, randomized, prospective 1-year study was conducted in men with primary or secondary osteoporosis. Patients were randomized to risedronate (risedronate 5 mg/day plus calcium 1,000 mg/day and vitamin D 800 IU/day) or control groups (alfacalcidol 1 mug/day plus calcium 500 mg/day or vitamin D 1,000 IU/day plus calcium 800 mg/day). Bone mineral density (BMD) measurements, X-rays of the spine, a medical history and physical exam, and patient self-assessments of back pain were performed at baseline and 12 months. Blinded semi-quantitative fracture assessment was conducted by a radiologist. A total of 316 men with osteoporosis were enrolled in the trial (risedronate, n=158; control, n=158). At 1 year lumbar spine BMD increased by 4.7% in the risedronate group versus an increase of 1.0% in the control group (P<0.001). Significant increases in BMD at the total hip and femoral neck were also observed with risedronate compared with the control group. The incidence of new vertebral fracture in the risedronate group was reduced by 60% versus the control group (P=0.028). Daily treatment with risedronate for 12 months significantly increased BMD at the lumbar spine, femoral neck and total hip and significantly reduced the incidence of new vertebral fractures. This is the first prospective, randomized, controlled trial to demonstrate a significant reduction in vertebral fractures in 1 year in men with primary or secondary osteoporosis.

  10. The Athens stroke registry: results of a five-year hospital-based study.

    PubMed

    Vemmos, K N; Takis, C E; Georgilis, K; Zakopoulos, N A; Lekakis, J P; Papamichael, C M; Zis, V P; Stamatelopoulos, S

    2000-01-01

    The advent and wide application of new technology, especially noninvasive techniques, has enabled physicians to more completely investigate and clarify the etiopathogenic mechanisms of stroke. Such data have not been available until recently for Southeastern Europe. In addition, during the last decades, strategies for the modification of risk factors and primary prevention may have changed the prevalence of each subgroup of stroke as well. We investigated 1, 042 consecutive patients who had first strokes, during a period of 5 years (from June 1992 to May 1997) and classified them prospectively based on etiopathogenic mechanisms. Patients with transient ischemic attacks and subarachnoid hemorrhage were excluded. There were 613 male and 429 female patients, with a mean age of 70.2 +/- 11.9 years. Forty-six percent of the patients arrived within 3 h from stroke onset. The probable mechanisms were: large-artery atherosclerosis, 156 (15%); lacunes, 177 (17%); cardioembolic, 335 (32.1%); infarct of unknown cause, 182 (17.5%); miscellaneous causes, 35 (3.3%), and intracerebral hemorrhage (ICH), 157 (15.1%). In the cardioembolic group, nonvalvular atrial fibrillation (NVAF) was the probable cause in 225 patients, especially in patients older than 75 years (65%). The overall hospital mortality was 15.2% (from 0.6% for lacunar stroke to 34% for ICH). In our population, cardioembolism is the most frequent subtype of stroke. NVAF is the most likely source, especially in older patients.

  11. Early micromovement of the Articular Surface Replacement (ASR) femoral component: two-year radiostereometry results.

    PubMed

    Penny, J O; Ding, M; Varmarken, J E; Ovesen, O; Overgaard, S

    2012-10-01

    Radiostereometric analysis (RSA) can detect early micromovement in unstable implant designs which are likely subsequently to have a high failure rate. In 2010, the Articular Surface Replacement (ASR) was withdrawn because of a high failure rate. In 19 ASR femoral components, the mean micromovement over the first two years after implantation was 0.107 mm (SD 0.513) laterally, 0.055 mm (SD 0.204) distally and 0.150 mm (SD 0.413) anteriorly. The mean backward tilt around the x-axis was -0.08° (SD 1.088), mean internal rotation was 0.165° (SD 0.924) and mean varus tilt 0.238° (SD 0.420). The baseline to two-year varus tilt was statistically significant from zero movement, but there was no significant movement from one year onwards. We conclude that the ASR femoral component achieves initial stability and that early migration is not the mode of failure for this resurfacing arthroplasty.

  12. Stability of alexithymia in late adolescence: results of a 4-year follow-up study.

    PubMed

    Karukivi, Max; Pölönen, Tuukka; Vahlberg, Tero; Saikkonen, Suvi; Saarijärvi, Simo

    2014-10-30

    The aim of the present study was to assess the stability of alexithymia in adolescents and the effects of parental factors and social support thereon. The sample comprised 315 late adolescents, of whom 259 were female and 56 male. At baseline, the mean age of the subjects was 19 years (range 17-21 years). The follow-up period was 4 years (2008-2012). The 20-item Toronto Alexithymia Scale (TAS-20) was used for the assessment of alexithymia both at baseline and follow-up. The Multidimensional Scale of Perceived Social Support (MSPSS) and the Parental Bonding Instrument (PBI) were used as measures at baseline. Regarding absolute stability, the changes in the TAS-20 total scores and two subscales (DIF and EOT) were statistically significant but the effect sizes for the changes were small (Cohen׳s d 0.21-0.24). The test-retest correlations for the TAS-20 total and subscale scores were high (ρ=0.50-0.64, P<0.001), indicating relative stability. While several parental and social support variables were associated with alexithymia at baseline, low social support from friends was the only to predict higher alexithymia at follow-up. Alexithymia is a stable personality trait also in late adolescence. Low social support from friends is related to alexithymia in young adulthood.

  13. French brain tumor database: 5-year histological results on 25 756 cases.

    PubMed

    Rigau, Valérie; Zouaoui, Sonia; Mathieu-Daudé, Hélène; Darlix, Amélie; Maran, Aurélie; Trétarre, Brigitte; Bessaoud, Faiza; Bauchet, Fabienne; Attaoua, Redha; Fabbro-Peray, Pascale; Fabbro, Michel; Kerr, Christine; Taillandier, Luc; Duffau, Hugues; Figarella-Branger, Dominique; Costes, Valérie; Bauchet, Luc

    2011-11-01

    This work aimed to prospectively record all primary central nervous system tumor (PCNST) cases in France, for which histological diagnosis is available. The objectives were to (i) create a national registry and a network to perform epidemiological studies; (ii) implement clinical and basic research protocols; and (iii) harmonize the health care of patients affected by PCNST. For 5 years, 25 756 cases of newly diagnosed and histologically confirmed PCNST have been recorded. Histological diagnoses included glioma (48.9%), all other neuroepithelial tumors (5%), meningioma (28.8%), nerve sheath tumors (8.4%), lymphoma (3.2%) and others (5.7%). Cryopreservation was reported for 6018 PCNST specimens. Tumor resections (R) were performed in 78% cases, while biopsies accounted for 22%. Median age (MA), sex, percentage R and number of cryopreserved tumors were detailed for each histology; for example, out of 6053 glioblastomas (MA 63 years, male 59.4%, R 62%, 1611 were cryopreserved), and out of 37 atypical teratoid/rhabdoid tumors (MA 2 years, male 56.8%, R 94%, 17 were cryopreserved). This database or databank dedicated to PCNST cases contains detailed data on clinical, histological and other characteristics, such as the inclusion of data on cryopreserved specimens that are not available in other European registries. Therefore, this is a valuable resource that can be used for planning future epidemiological and clinical research.

  14. Twenty-two years of candidaemia surveillance: results from a Norwegian national study.

    PubMed

    Hesstvedt, L; Gaustad, P; Andersen, C T; Haarr, E; Hannula, R; Haukland, H H; Hermansen, N-O; Larssen, K W; Mylvaganam, H; Ranheim, T E; Sandven, P; Nordøy, I; Kanestrøm, A; Grub, C; Onken, A; Thielsen, C; Skaare, D; Tofteland, S; Sønsteby, L-J; Hjetland, R; Hide, R; Vik, E; Kümmel, A; Åsheim, S

    2015-10-01

    Several studies have reported an increased incidence of candidaemia and a redistribution of species, with a decrease in the number of Candida albicans isolates. In Norway, a prospective, national surveillance study of candidaemia has been ongoing since 1991. Data from the period 1991-2003 have been published previously. The aim of this study was to follow up the incidence, species distribution and antifungal susceptibility of Candida species isolates from blood cultures in the period 2004-2012, and compare them with the corresponding findings from the period 1991-2003. Blood culture isolates of Candida species from all medical microbiological laboratories in Norway were identified and susceptibility tested at the Norwegian Mycological Reference Laboratory. A total of 1724 isolates were recovered from 1653 patients in the period 2004-2012. Comparison of the two periods showed that the average incidence of candidaemia episodes per 100 000 inhabitants increased from 2.4 (1991-2003) to 3.9 (2004-2012). The increase in incidence in the latter period was significantly higher in patients aged >40 years (p 0.001), and a marked increase was observed in patients aged >60 years (p < 0.001). In conclusion, the average incidence in Norway over a period of 22 years modestly increased from 2.4 to 3.9 per 100,000 inhabitants, this being mainly accounted for by candidaemia in the elderly. The species distribution was stable, and the rate of acquired resistance was low.

  15. Eight-year results of site retention of anorganic bovine bone and anorganic bovine matrix.

    PubMed

    Degidi, Marco; Perrotti, Vittoria; Piattelli, Adriano; Iezzi, Giovanna

    2013-12-01

    The long-term fate of some biomaterials is still unknown, and the reports present in the literature are not conclusive as to whether these biomaterials are resorbed over time or not. Different reports can be found with regard to the resorption behavior of anorganic bovine bone (ABB). The aim of the present study was to provide a comparative histological and histomorphometrical evaluation, in the same patient, of 2 specimens retrieved from a sinus augmented with ABB and with anorganic bovine matrix added to a cell-binding peptide (PepGen P-15), respectively, after a healing period of 6 months and after 8 years of implant loading, to evaluate the resorption of both biomaterials. A unilateral sinus augmentation procedure with ABB (50%) and with PepGen P-15 (50%) was performed in a 54-year-old male patient. Two titanium dental implants with a sandblasted and acid-etched surface were inserted after 6 months. During this procedure, 2 tissue cores were retrieved from the sinus with a trephine, before implant insertion. After an additional 6 months, a fixed prosthetic restoration was fabricated. One of these implants, after a loading period of 8 years, fractured in the coronal portion and was removed. Both specimens, one retrieved after a 6-month healing period and the other after an 8-year loading period, were treated to obtain thin ground sections. In the 6-month specimen, the histomorphometry showed that the percentage of newly formed bone was 27.2% ± 3.6%, marrow spaces 35.6% ± 2.3%, residual ABB particles 25.1% ± 1.2%, and residual PepGen P-15 particles 12.1% ± 2.2%. In the 8-year specimen, the histomorphometry showed that the percentage of newly formed bone was 51.4% ± 4.8%, marrow spaces 40% ± 7.1%, residual ABB particles 6.2% ± 0.7%, and residual PepGen P-15 particles 2.4% ± 0.5%. Both biomaterials underwent significant resorption over the course of this study.

  16. [Tubulo-villous rectal tumours. Results of surgical resection in relation to histotype (30 years' experience)].

    PubMed

    Carditello, Antonio; Milone, Antonino; Paparo, Domenica; Anastasi, Giuliana; Mollo, Francesco; Stilo, Francesco

    2004-01-01

    Adenomas of the rectum are frequently found during endoscopic examination. We report on our 30 years of experience with the treatment of tubulo-villous adenomas based on histotype. Between 1971 and 2001, 104 villous tumours of the rectum were treated surgically. The patients' average age was 65 years. These were sessile tumours in 69% of cases, pedunculated in 17.5% and flowing tumours in 13.5%. The mean tumour size was 3 cm. They were associated with colon cancer in 15% of cases and with polyadenoma in 10%. They were located in the rectum within 0 to 6 cm of the anal margin in half the cases. These tumours were treated by local excision in 74 cases and by wide excision in 30 cases. The malignant potential of the tumours was 30%, including 10% invasive malignancy. There were no surgical fatalities, but a 6% medical fatality rate was registered. There was a 20% complication rate related to the surgical technique. Twenty patients were lost to follow-up. Out of 84 villous tumours, monitored over a mean survival period of 6.5 years, there were 24 recurrences: 18 underwent endoscopic excision and in 6 cases a wide resection. The various tumour resection techniques and the operative indications of variable difficulty are presented. It would seem, at present, that total resection of the rectum with a colo-anal anastomosis is the best treatment for large flowing villous tumours occupying almost the entire rectum. Thorough preoperative examination and the mastering of various surgical procedures should allow the most suitable choice of treatment for each individual case.

  17. Nine-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Cosmological Parameter Results

    NASA Technical Reports Server (NTRS)

    Hinshaw, G.; Larson, D.; Komatsu, E.; Spergel, D. N.; Bennett, C. L.; Dunkley, J.; Nolta, M. R.; Halpern, M.; Hill, R. S.; Odegard, N.; Page, L.; Smith, K. L.; Weiland, J. L.; Gold, B.; Jarosik, N.; Kogut, A.; Limon, M.; Meyer, S. S.; Tucker, G. S.; Wollack, E.; Wright, E. L.

    2013-01-01

    We present cosmological parameter constraints based on the final nine-year Wilkinson Microwave Anisotropy Probe (WMAP) data, in conjunction with a number of additional cosmological data sets. The WMAP data alone, and in combination, continue to be remarkably well fit by a six-parameter Lambda-CDM model. When WMAP data are combined with measurements of the high-l cosmic microwave background anisotropy, the baryon acoustic oscillation scale, and the Hubble constant, the matter and energy densities Omega(sub b)h(exp 2), Omega(sub c)h(exp 2)and Omega(sub Lambda), are each determined to a precision of approx. 1.5%. The amplitude of the primordial spectrum is measured to within 3%, and there is now evidence for a tilt in the primordial spectrum at the 5 sigma level, confirming the first detection of tilt based on the five-year WMAP data. At the end of the WMAP mission, the nine-year data decrease the allowable volume of the six-dimensional Lambda-CDM parameter space by a factor of 68,000 relative to pre-WMAP measurements. We investigate a number of data combinations and show that their Lambda-CDM parameter fits are consistent. New limits on deviations from the six-parameter model are presented, for example: the fractional contribution of tensor modes is limited to r < 0.13 (95% CL); the spatial curvature parameter is limited to Omega(sub kappa) = (0.0027 (sub +0.0039) (sup -0.0038;) the summed mass of neutrinos is limited to Sigma M(sub nu) < 0.44 eV (95% CL); and the number of relativistic species is found to lie within N(sub eff) = 3.84 +/- 0+/-40, when the full data are analyzed. The joint constraint on N(sub eff) and the primordial helium abundance, Y(sub He), agrees with the prediction of standard big bang nucleosynthesis. We compare recent Planck measurements of the Sunyaev-Zel'dovich effect with our seven-year measurements, and show their mutual agreement. Our analysis of the polarization pattern around temperature extrema is updated. This confirms a fundamental

  18. Emulytics for Cyber-Enabled Physical Attack Scenarios: Interim LDRD Report of Year One Results.

    SciTech Connect

    Clem, John; Urias, Vincent; Atkins, William Dee; Symonds, Christopher J.

    2015-12-08

    Sandia National Laboratories has funded the research and development of a new capability to interactively explore the effects of cyber exploits on the performance of physical protection systems. This informal, interim report of progress summarizes the project’s basis and year one (of two) accomplishments. It includes descriptions of confirmed cyber exploits against a representative testbed protection system and details the development of an emulytics capability to support live, virtual, and constructive experiments. This work will support stakeholders to better engineer, operate, and maintain reliable protection systems.

  19. Sabril® registry 5-year results: Characteristics of adult patients treated with vigabatrin.

    PubMed

    Krauss, Gregory; Faught, Edward; Foroozan, Rod; Pellock, John M; Sergott, Robert C; Shields, W Donald; Ziemann, Adam; Dribinsky, Yekaterina; Lee, Deborah; Torri, Sarah; Othman, Feisal; Isojarvi, Jouko

    2016-03-01

    Vigabatrin (Sabril®), approved in the US in 2009, is currently indicated as adjunctive therapy for refractory complex partial seizures (rCPS) in patients ≥ 10 years old who have responded inadequately to several alternative treatments and as monotherapy for infantile spasms (IS) in patients 1 month to 2 years of age. Because of reports of vision loss following vigabatrin exposure, FDA approval required a risk evaluation mitigation strategy (REMS) program. Vigabatrin is only available in the US through Support, Help, And Resources for Epilepsy (SHARE), which includes a mandated registry. This article describes 5 years of demographic and treatment exposure data from adult patients (≥ 17 years old) in the US treated with vigabatrin and monitored in the ongoing Sabril® registry. Registry participation is mandatory for all US Sabril® prescribers and patients. A benefit-risk assessment must be documented by the physician for a patient to progress to maintenance therapy, defined as 1 month of vigabatrin treatment for patients with IS and 3 months for patients with rCPS. Ophthalmologic assessments must be documented during and after completion of therapy. As of August 26, 2014, a total of 6823 patients were enrolled in the registry, of which 1200 were adults at enrollment. Of these patients, 1031 (86%) were naïve to vigabatrin. The majority of adult patients (n=783, 65%) had previously been prescribed ≥ 4 AEDs, and 719 (60%) were receiving ≥ 3 concomitant AEDs at vigabatrin initiation. Prescribers submitted an initial ophthalmological assessment form for 863 patients; an ophthalmologic exam was not completed for 300 (35%) patients and thus, were considered exempted from vision testing. Of these patients, 128 (43%) were exempted for neurologic disabilities. Clinicians discontinued treatment in 8 patients because of visual field deficits (VFD) (5 patients naïve to vigabatrin and 3 patients previously exposed). Based on Kaplan-Meier survival estimates, it is

  20. Four Years of Practical Arrangements between IAEA and Moscow SIA 'Radon': Preliminary Results - 13061

    SciTech Connect

    Batyukhnova, O.G.; Karlina, O.K.; Neveikin, P.P.

    2013-07-01

    The International Education Training Centre (IETC) at Moscow State Unitary Enterprise Scientific and Industrial Association 'Radon' (SIA 'Radon'), in co-operation with the International Atomic Energy Agency (IAEA), has developed expertise and provided training to waste management personnel for the last 15 years. Since 1997, the educational system of the enterprise with the support of the IAEA has acquired an international character: more than 470 experts from 35 countries- IAEA Member States completed the professional development. Training is conducted at various thematic courses or fellowships for individual programs and seminars on IAEA technical projects. In June 2008 a direct agreement (Practical Arrangements) was signed between SIA 'Radon' and the IAEA on cooperation in the field of development of new technologies, expert's advice to IAEA Member States, and, in particular, the training of personnel in the field of radioactive waste management (RWM), which opens up new perspectives for fruitful cooperation of industry professionals. The paper summarizes the current experience of the SIA 'Radon' in the organization and implementation of the IAEA sponsored training and others events and outlines some of strategic educational elements, which IETC will continue to pursue in the coming years. (authors)

  1. Results of the prospective evaluation of radial keratotomy (PERK) study one year after surgery.

    PubMed

    Waring, G O; Lynn, M J; Gelender, H; Laibson, P R; Lindstrom, R L; Myers, W D; Obstbaum, S A; Rowsey, J J; McDonald, M B; Schanzlin, D J

    1985-02-01

    The Prospective Evaluation of Radial Keratotomy (PERK) study is a nine-center, self-controlled clinical trial of a standardized technique of radial keratotomy in 435 patients who had physiologic myopia with a preoperative refraction between -2.00 and -8.00 diopters. The surgical technique consisted of eight incisions using a diamond micrometer knife with blade length determined by intraoperative ultrasonic pachymetry and the diameter of central clear zone determined by preoperative refraction. At one year after surgery, myopia was reduced in all eyes; 60% were within +/- 1.00 diopter of emmetropia; 30% were undercorrected and 10% were overcorrected by more than 1.00 diopter (range of refraction, -4.25 to +3.38 D). Uncorrected visual acuity was 20/40 or better in 78% of eyes. The operation was most effective in eyes with a refraction between -2.00 and -4.25 diopters. Thirteen percent of patients lost one or two Snellen lines of best corrected visual acuity. However, all but three eyes could be corrected to 20/20. Ten percent of patients increased astigmatism more than 1.00 diopter. Disabling glare was not detected with a clinical glare tester, but three patients reduced their driving at night because of glare. Between six months and one year, the refraction changed by greater than 0.50 diopters in 19% of eyes.

  2. Treatment performances of French constructed wetlands: results from a database collected over the last 30 years.

    PubMed

    Morvannou, A; Forquet, N; Michel, S; Troesch, S; Molle, P

    2015-01-01

    Approximately 3,500 constructed wetlands (CWs) provide raw wastewater treatment in France for small communities (<5,000 people equivalent). Built during the past 30 years, most consist of two vertical flow constructed wetlands (VFCWs) in series (stages). Many configurations exist, with systems associated with horizontal flow filters or waste stabilization ponds, vertical flow with recirculation, partially saturated systems, etc. A database analyzed 10 years earlier on the classical French system summarized the global performances data. This paper provides a similar analysis of performance data from 415 full-scale two-stage VFCWs from an improved database expanded by monitoring data available from Irstea and the French technical department. Trends presented in the first study are confirmed, exhibiting high chemical oxygen demand (COD), total suspended solids (TSS) and total Kjeldahl nitrogen (TKN) removal rates (87%, 93% and 84%, respectively). Typical concentrations at the second-stage outlet are 74 mgCOD L(-1), 17 mgTSS L(-1) and 11 mgTKN L(-1). Pollutant removal performances are summarized in relation to the loads applied at the first treatment stage. While COD and TSS removal rates remain stable over the range of applied loads, the spreading of TKN removal rates increases as applied loads increase.

  3. Summary of the results from the lunar orbiter laser altimeter after seven years in lunar orbit

    NASA Astrophysics Data System (ADS)

    Smith, David E.; Zuber, Maria T.; Neumann, Gregory A.; Mazarico, Erwan; Lemoine, Frank G.; Head, James W., III; Lucey, Paul G.; Aharonson, Oded; Robinson, Mark S.; Sun, Xiaoli; Torrence, Mark H.; Barker, Michael K.; Oberst, Juergen; Duxbury, Thomas C.; Mao, Dandan; Barnouin, Olivier S.; Jha, Kopal; Rowlands, David D.; Goossens, Sander; Baker, David; Bauer, Sven; Gläser, Philipp; Lemelin, Myriam; Rosenburg, Margaret; Sori, Michael M.; Whitten, Jennifer; Mcclanahan, Timothy

    2017-02-01

    In June 2009 the Lunar Reconnaissance Orbiter (LRO) spacecraft was launched to the Moon. The payload consists of 7 science instruments selected to characterize sites for future robotic and human missions. Among them, the Lunar Orbiter Laser Altimeter (LOLA) was designed to obtain altimetry, surface roughness, and reflectance measurements. The primary phase of lunar exploration lasted one year, following a 3-month commissioning phase. On completion of its exploration objectives, the LRO mission transitioned to a science mission. After 7 years in lunar orbit, the LOLA instrument continues to map the lunar surface. The LOLA dataset is one of the foundational datasets acquired by the various LRO instruments. LOLA provided a high-accuracy global geodetic reference frame to which past, present and future lunar observations can be referenced. It also obtained high-resolution and accurate global topography that were used to determine regions in permanent shadow at the lunar poles. LOLA further contributed to the study of polar volatiles through its unique measurement of surface brightness at zero phase, which revealed anomalies in several polar craters that may indicate the presence of water ice. In this paper, we describe the many LOLA accomplishments to date and its contribution to lunar and planetary science.

  4. Curative resection in Zollinger-Ellison syndrome. Results of a 10-year prospective study.

    PubMed Central

    Norton, J A; Doppman, J L; Jensen, R T

    1992-01-01

    Since 1980, 73 patients with Zollinger-Ellison syndrome (ZES) without radiographic evidence of liver metastases were studied on a prospective protocol including medical management of gastric acid hypersecretion, extensive radiographic tumor localization, and exploratory surgery to find and resect gastrinoma for potential cure. Each patient had gastric acid hypersecretion effectively controlled with either H2-blockers or omeprazole. Patients were divided prospectively into two groups, with all patients undergoing the same preoperative localization studies and extensive laparotomy. In contrast to group 1 (1980-1986) (36 patients), group 2 (1987-Oct. 1990) (37 patients) also underwent additional procedures (transillumination and duodenotomy) at surgery to find duodenal gastrinomas. Preoperative imaging studies localized tumor in 38 (52%) patients, and portal venous sampling for gastrin determinations was positive in 49 (67%) patients. Gastrinomas were found and resected in 57 (78%) patients. Significantly more gastrinomas (92% of patients) were found in group 2 than in group 1 patients (64%) (p less than 0.01). This increase was due to increased numbers of duodenal gastrinomas in group 2 than in group 1 patients (43% versus 11%; p less than 0.01). The increased ability to find duodenal gastrinomas did not significantly improve the immediate disease-free rate, which was 58% for all patients. Duodenal primary gastrinomas were found to have a significantly greater incidence of metastases (55%) and a significantly shorter disease-free interval (12 months) than pancreatic gastrinomas (22% and 84 months, respectively) suggesting that duodenal gastrinomas may be more malignant and not more frequently curable than pancreatic gastrinomas. Operations were performed with no deaths and 11% morbidity rate. Long-term follow-up showed that 50% of patients initially rendered disease free would develop recurrent disease by 5 years. Survival was excellent for all patients, and none

  5. Observing Global Ocean Circulation From Space: The First Year's Results From the TOPEX/POSEIDON Mission

    NASA Technical Reports Server (NTRS)

    Fu, L. -L.

    1993-01-01

    The joint U.S./France TOPEX/Poseidon satellite was launched on August 10, 1992, and became operational 43 days later. The major goal of the mission is to use a radar altimeter system for making precise measurements of the height of the sea surface for the study of the dynamics of large-scale ocean circulation, which is a key to understanding global climate change. Additionally, the data are used for studying ocean tides and marine geophysics. The radar altimeter also measures wave height and wind speed. The mission is being conducted to optimize the sea surface height measurements for a minimum of three years. The primary objective of the first six months of the mission was to calibrate and validate the mission's measurements...

  6. Contamination control program results from three years of ground operations on the Extreme Ultraviolet Explorer instruments

    NASA Technical Reports Server (NTRS)

    Ray, David C.; Jelinsky, Sharon; Welsh, Barry Y.; Malina, Roger F.

    1990-01-01

    A stringent contamination-control plan has been developed for the optical components of the Extreme Ultraviolet Explorer instruments, whose performance in the 80-900 A wavelength range is highly sensitive to particulate and molecular contamination. The contamination-control program has been implemented over the last three years during assembly, test and calibration phases of the instrument. These phases have now been completed and the optics cavities of the instruments have been sealed until deployment in space. Various approaches are discussed which have been used during ground operations to meet optics' contamination goals within the project schedule and budget. The measured optical properties of EUV witness mirrors are also presented which remained with the flight mirrors during ground operations. These were used to track optical degradation due to contamination from the cleanroom and high-vacuum test-chamber environments.

  7. The DOTS strategy in China: results and lessons after 10 years.

    PubMed Central

    Xianyi, Chen; Fengzeng, Zhao; Hongjin, Duanmu; Liya, Wan; Lixia, Wang; Xin, Du; Chin, Daniel P.

    2002-01-01

    OBJECTIVE: To analyse the five-point tuberculosis (TB) strategy, DOTS, 10 years after its implementation in one-half of China's population, and to suggest lessons for future implementation of the DOTS strategy. METHODS: We analysed trends in case-finding and treatment outcome over time following implementation of the DOTS strategy in each county, using routine reporting data from the Infectious and Endemic Disease Control (IEDC) project (1991 - 2000). We also determined the proportion of counties with different levels of case-finding for the fifth and sixth years of DOTS implementation. FINDINGS: From 1991 to 1995, DOTS expanded rapidly to cover more than 90% of target population and counties. By 2000, 8 million TB suspects had received free diagnostic evaluation: 1.8 million TB cases were diagnosed, free treatment was provided to 1.3 million smear-positive cases, and more than 90% were cured. During DOTS implementation, the percentage of previously treated cases decreased among all smear-positive cases and treatment outcomes improved. Despite these achievements, the detection rate for new smear-positive cases in the project was estimated to be only 54% in 1998, and 41.2% of the counties had a below average or low level of case-finding (with substantial variation between provinces). CONCLUSIONS: The IEDC project demonstrated that it is feasible to rapidly expand DOTS on a large scale. The global target of an 85% cure rate was quickly achieved, and the level of drug-resistance was probably reduced by this project. However, case-detection did not reach the 70% global target, and more research is needed on how to enhance this. PMID:12131998

  8. Teaching hematology to second year medical students: results of a national survey of hematology course directors.

    PubMed

    Broudy, Virginia C; Hickman, Scot

    2007-04-01

    Increasing clinical productivity expectations at academic medical centers and new faculty effort reporting requirements for NIH-supported investigators challenge the tradition of faculty volunteerism for medical student teaching. To better define the structure, content, and financial support of second year medical school hematology courses nationwide, we mailed a survey to the hematology course directors at 85 of the 125 accredited US medical schools. The 58 course directors who returned the survey represent all regions of the US and both public and private medical schools. Median class size was 150 students (range 40-200), and some courses included a substantial proportion (up to 33%) of other types of students. The median number of hours per course was 33 h (range 8 to 74). Approximately 50% of the total teaching time was devoted to lecture (range 5 to 100%). Web-based teaching was used by 62% of course directors. The median number of faculty responsible for teaching the second year hematology course was 12 (range 1-36). The hematology course directors identified a number of obstacles, including difficulty in recruiting teachers, the lack of well-defined content, and the very modest budget (less than $1,500 for most courses). Only three of the course directors indicated that they received salary support for this role. These findings suggest that a national effort to define learning objectives for the hematology courses and to share teaching materials among medical schools is warranted. Little financial support is provided for the hematology course, and these findings compel the identification of resources to pay faculty for teaching medical student required courses.

  9. Treatment of contained lumbar disc herniations using radiofrequency assisted micro-tubular decompression and nucleotomy: four year prospective study results

    PubMed Central

    2014-01-01

    Background Patients with radiculopathy caused by contained disc herniations are less likely to have good outcomes following discectomy surgery than patients with disc herniations that are not contained. The author presents his 4-year results from a prospective trial regarding the efficacy and safety of a tubular transforaminal radiofrequency-assisted manual decompression and annulus modulation of contained disc herniations in 58 patients. Methods Fifty-eight patients with lumbar radiculopathy due to a contained disc herniation were enrolled in a prospective clinical study. Visual analog scores (VAS) for back pain and leg pain, quality of life assessment, Macnab criteria, and SF-12 were collected from patients before treatment, at 2-years and 4-years post-treatment. Results At 4 years, results were obtained from 47 (81%) of patients. Compared to mean pre- treatment assessments, mean 4-year VAS for back pain improved from 8.6 to 2.3 points, and mean VAS for leg pain improved from 7.8 to 2.3. Eighty-three percent of respondents reported that they were “satisfied” or “very satisifed” with their quality of life at 4-years as per SF-12. At 4 years, recurrence was noted in 3 (6.4%) of respondents and no complications were reported. Conclusions The 2-year and 4-year study results are nearly identical, suggesting durable benefit out to 4 years. These results also suggest that in carefully selected patients with sustained contained disc herniations who have failed conservative treatments, manual decompression combined with radiofrequency-assisted decompression and annulus modulation are very likely to have good outcomes 4 years post-treatment. PMID:25694932

  10. [Analysis of the results of the SEIMC External Quality Control Program. Year 2009].

    PubMed

    de Gopegui Bordes, Enrique Ruiz; del Remedio Guna Serrano, M; Orta Mira, Nieves; Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción; Pérez, José L

    2011-03-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) includes controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. In this article, the most important conclusions and lessons from the 2009 controls are presented. As a whole, the results obtained in 2009 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. The results of this program highlight the need to implement both internal and external controls in order to ensure maximal quality of microbiological tests.

  11. [Analysis of the results of the SEIMC External Quality Control Program. Year 2012].

    PubMed

    de Gopegui Bordes, Enrique Ruiz; Guna Serrano, M del Remedio; Orta Mira, Nieves; Ovies, María Rosario; Poveda, Marta; Gimeno Cardona, Concepción

    2014-02-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2012 controls. As a whole, the results obtained in 2012 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests.

  12. [Analysis of the results of the SEIMC External Quality Control Program. Year 2014].

    PubMed

    Gopegui Bordes, Enrique Ruiz de; Guna Serrano, M Del Remedio; Orta Mira, Nieves; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2016-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2014 controls. As a whole, the results obtained in 2014 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of the SEIMC program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests.

  13. [Analysis of the results of the SEIMC External Quality Control Program. Year 2013].

    PubMed

    de Gopegui Bordes, Enrique Ruiz; Orta Mira, Nieves; Del Remedio Guna Serrano, M; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2015-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, molecular microbiology and HIV-1, HCV and HBV viral loads. This manuscript presents the analysis of results obtained of the participants from the 2013 SEIMC External Quality Control Programme, except viral loads controls, that they are summarized in a manuscript abroad. As a whole, the results obtained in 2013 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests.

  14. Preterm birth results in alterations in neural connectivity at age 16 years.

    PubMed

    Mullen, Katherine M; Vohr, Betty R; Katz, Karol H; Schneider, Karen C; Lacadie, Cheryl; Hampson, Michelle; Makuch, Robert W; Reiss, Allan L; Constable, R Todd; Ment, Laura R

    2011-02-14

    Very low birth weight preterm (PT) children are at high risk for brain injury. Employing diffusion tensor imaging (DTI), we tested the hypothesis that PT adolescents would demonstrate microstructural white matter disorganization relative to term controls at 16 years of age. Forty-four PT subjects (600-1250 g birth weight) without neonatal brain injury and 41 term controls were evaluated at age 16 years with DTI, the Wechsler Intelligence Scale for Children-III (WISC), the Peabody Picture Vocabulary Test-Revised (PPVT), and the Comprehensive Test of Phonological Processing (CTOPP). PT subjects scored lower than term subjects on WISC full scale (p=0.003), verbal (p=0.043), and performance IQ tests (p=0.001), as well as CTOPP phonological awareness (p=0.004), but scored comparably to term subjects on PPVT and CTOPP Rapid Naming tests. PT subjects had lower fractional anisotropy (FA) values in multiple regions including bilateral uncinate fasciculi (left: p=0.01; right: p=0.004), bilateral external capsules (left: p<0.001; right: p<0.001), the splenium of the corpus callosum (p=0.008), and white matter serving the inferior frontal gyrus bilaterally (left: p<0.001; right: p=0.011). FA values in both the left and right uncinate fasciculi correlated with PPVT scores (a semantic language task) in the PT subjects (left: r=0.314, p=0.038; right: r=0.336, p=0.026). FA values in the left and right arcuate fasciculi correlated with CTOPP Rapid Naming scores (a phonologic task) in the PT subjects (left: r=0.424, p=0.004; right: r=0.301, p=0.047). These data support for the first time that dual pathways underlying language function are present in PT adolescents. The striking bilateral dorsal correlations for the PT group suggest that prematurely born subjects rely more heavily on the right hemisphere than typically developing adults for performance of phonological language tasks. These findings may represent either a delay in maturation or the engagement of alternative neural

  15. 10 years of cloud droplet activation data from Pallas, Northern Finland - preliminary results

    NASA Astrophysics Data System (ADS)

    Kivekäs, Niku; Asmi, Eija; Brus, David; Komppula, Mika; Lihavainen, Heikki

    2016-04-01

    Activation of atmospheric aerosol particles into cloud droplets has been studied in situ at Pallas measurement station in Finnish Lapland from year 2005 to present day. The site is located on a hill top, about 300 m above the surrounding lowlands, and it is inside a cloud for 15 % of time. Here in-cloud periods are defined as periods when visibility was below 1000 m. There are two parallel Differential Mobility Particle Sizers (DMPS) at the site, measuring the number concentration and dry size distribution of atmospheric aerosol particles. One DMPS is connected to a PM2.5 inlet, the other to a total air inlet with no cut-off diameter. After each inlet the particles are dried to evaporate any water in them. This way it is possible to measure simultaneously the dry number-size-distribution of all particles, and that of particles with wet diameter smaller than 2.5 m. As the latter does not include cloud droplets, the difference between the two measurements represents the number concentration and size distribution of those particles that have activated into cloud droplets. The number concentration of particles at Pallas has a clear seasonal cycle, being highest during summer and lowest during winter. The monthly mean number concentration of particles with diameter larger than 100 nm varied from 38 cm-3 in November to 270 cm-3 in July. During in-cloud periods the monthly mean number concentration of activated particles of this same size class showed a similar pattern, varying from 23 cm-3 (November) to 110 cm-3 in April. The monthly mean D50 activation diameter (diameter at which 50 % of particles activate) varied from 85 nm (February) to 189 nm (July), showing an average 0.1 nm increase for each added particle with diameter > 100 nm. The activated fraction of particles in all sizes decreased sharply when visibility exceeded 1000 m. The highest activated fractions of particles were not observed during the periods of the thickest clouds, but during clouds with in

  16. Preterm Birth Results in Alterations in Neural Connectivity at Age 16 Years

    PubMed Central

    Mullen, Katherine M.; Vohr, Betty R.; Katz, Karol H.; Schneider, Karen C.; Lacadie, Cheryl; Hampson, Michelle; Makuch, Robert W.; Reiss, Allan R.; Constable, R. Todd; Ment, Laura R.

    2010-01-01

    Very low birth weight preterm (PT) children are at high risk for brain injury. Employing diffusion tensor imaging (DTI), we tested the hypothesis that PT adolescents would demonstrate microstructural white matter disorganization relative to term controls at 16 years of age. Forty-four PT subjects (600 - 1250 grams birth weight) without neonatal brain injury and 41 term controls were evaluated at age 16 years with DTI, the Wechsler Intelligence Scale for Children - III (WISC), the Peabody Picture Vocabulary Test - Revised (PPVT), and the Comprehensive Test of Phonological Processing (CTOPP). PT subjects scored lower than term subjects on WISC full scale (p = 0.003), verbal (p = 0.043), and performance IQ tests (p = 0.001), as well as CTOPP phonological awareness (p = 0.004), but scored comparably to term subjects on PPVT and CTOPP Rapid Naming tests. PT subjects had lower fractional anisotropy (FA) values in multiple regions including bilateral uncinate fasciculi (left: p = 0.01; right: p = 0.004), bilateral external capsules (left: p < 0.001; right: p < 0.001), the splenium of the corpus callosum (p = 0.008), and white matter serving the inferior frontal gyrus bilaterally (left: p < 0.001; right: p = 0.011). FA values in both the left and right uncinate fasciculi correlated with PPVT scores (a semantic language task) in the PT subjects (left: r = 0.314, p = 0.038; right: r = 0.336, p = 0.026). FA values in the left and right arcuate fasciculi correlated with CTOPP Rapid Naming scores (a phonologic task) in the PT subjects (left: r = 0.424, p = 0.004; right: r = 0.301, p = 0.047). These data support for the first time that dual pathways underlying language function are present in PT adolescents. The striking bilateral dorsal correlations for the PT group suggest that prematurely born subjects rely more heavily on the right hemisphere than typically developing adults for performance of phonological language tasks. These findings may represent either a delay in

  17. Summary of Mode Deactivation Therapy, Cognitive Behavior Therapy and Social Skills Training with Two Year Post Treatment Results

    ERIC Educational Resources Information Center

    Apsche, Jack A.; Bass, Christopher K.; Siv, Alexander M.

    2006-01-01

    This study summarized two treatment research studies and included recidivism data for two years post discharge for group therapy. The study compared Mode deactivation Therapy (MDT), Cognitive Behavior Therapy (CBT), and Social Skills training (SST), results of the MDT series of studies and the two year post-study recidivism data. The data from the…

  18. Upper extremity snowboarding injuries. Ten-year results from the Colorado snowboard injury survey.

    PubMed

    Idzikowski, J R; Janes, P C; Abbott, P J

    2000-01-01

    A survey of snowboarding injuries was conducted over 10 seasons (1988 to 1998). A questionnaire evaluating 20 variables was used to collect data from 47 medical facilities near Colorado ski resorts. A total of 7430 snowboarding-related injuries were seen. A control group consisted of 3107 noninjured snowboarders. Most of those injured were 30 years of age or younger; 74% of injuries occurred in men and 26% in women; 39% of injured snowboarders were beginners and 61% were intermediate or experts. Men rode at more advanced levels than women. Injured snowboarders were more likely than noninjured snowboarders to be beginners. There were 3645 (49.06% of total) upper extremity injuries; 56.43% were fractures, 26.78% sprains, and 9.66% dislocations. The most common site of injury was the wrist (21.6% of all snowboarding injuries). Wrist fractures (except to the scaphoid) and sprains were more common in beginners, women, and younger age groups. Intermediate and expert men were more likely to sustain hand, elbow, and shoulder injuries, as well as more severe injuries. Falling was the predominant mechanism of upper extremity injuries. Snowboarders who wore protective wrist guards were half as likely to sustain wrist injuries as those who did not wear guards.

  19. [Frequency of recurrent convulsions after a first febrile seizure: two-year observation results].

    PubMed

    Mustafić, Nevzeta; Tahirović, Husref; Trnovcević, Jasmina

    2010-01-01

    Febrile convulsions are the most frequent neurological disorder of early childhood. One third of children with febrile convulsions will have a recurrence, and only a small number will develop afebrile convulsions with epilepsy variation. The aim of the work was to establish the frequency of convulsion recurrence through the retrospective study with regard to age, type of recurrence, and applied prophylaxis in children in Tuzla Canton in a two-year period after the first febrile convulsion. Amongst 716 patients, 21.9% had a recurrence. Recurrence of simple febrile convulsions occurred in 124 (78.9%), complex in 18 (11.5%), and 14 (9.8%) patients had afebrile convulsions. There was no statistically significant difference in recurrence appearance between patients who received continuous and intermittent prophylaxis or different type of continuous prophylaxis. Knowledge of recurrence frequency according to age groups opens the possibility of recurrence prevention with adequate therapeutic measures, especially in home care conditions. Good parent education would represent the first step in recurrence prevention.

  20. 125 years of glacier survey of the Austrian Alpine Club: results and future challenges

    NASA Astrophysics Data System (ADS)

    Fischer, Andrea

    2016-04-01

    One of the aims of the German and Austrian Alpine Club was the scientific investigation of the Alps. In 1891, several years after Swiss initiatives, Richter put out a call to contribute to regular glacier length surveys in the Eastern Alps. Since then more than 100 glaciers have been surveyed on a first biannual and later annual basis. The database includes measured data showing a general glacier retreat since 1891, with two periods of glacier advances in the 1920s and 1980s. Less well known are the sketches and reports which illustrate, for instance, changes in surface texture. The interpretation of length change data requires a larger sample of data for a reasonable interpretation on a regional scale. Nearly every time series in the long history of investigation includes gaps, e.g. in cases of problematic snout positions on steep rock walls or in lakes, or of debris-covered tongues. Current climate change adds the problem of glaciers splitting up into several smaller glaciers which behave differently. Several basic questions need to be addressed to arrive at a most accurate prolongated time series: How should measurements on disintegrating or debris-covered (and thus more or less stagnating) glaciers be documented, and how can we homogenize length change time series? Despite of uncertainties, length change data are amongst the longest available records, bridging the gap to moraine datings of the early holocene.

  1. Effectiveness and relevance of MR acceptance testing: results of an 8 year audit.

    PubMed

    McRobbie, D W; Quest, R A

    2002-06-01

    The effectiveness and relevance of independent acceptance testing was assessed by means of an audit of acceptance procedures for 17 MRI systems, with field strengths in the range 0.5-1.5 T, acquired over 8 years. Signal-to-noise ratio and geometric linearity were found to be the image quality parameters most likely to fall below acceptable or expected standards. These received confirmed successful corrective action in 69% of instances. Non-uniformity, ghosting and poor fat suppression were the next most common non-compliant parameters, but yielded less satisfactory outcomes. Spatial resolution was not found to be a sensitive parameter in determining acceptability. 49% of all non-compliant parameters received verifiable corrective attention. A schedule of actual acceptance criteria is presented and shown to be reasonable. Parameter failure rates were shown not to have improved with time. A safety audit of 11 of the installations revealed the most common failings to be inadequate suite layout and poor use of signs. The mean number of safety issues per installation identified as requiring attention was 5, from a questionnaire of 100 points. A number of anecdotal errors and omissions are reported. The data support the importance of an appropriate acceptance procedure for new clinical MRI equipment and for the involvement of a suitably qualified safety adviser on the project team from the outset.

  2. Stereotactic posteroventral pallidotomy: clinical methods and results at 1-year follow up.

    PubMed

    Dalvi, A; Winfield, L; Yu, Q; Côté, L; Goodman, R R; Pullman, S L

    1999-03-01

    Twenty consecutive patients with idiopathic Parkinson's disease underwent stereotactic posteroventral pallidotomy. Schwab and England ADL scores in the "off" state were improved by 18% and in the "on" state the scores declined by 2%. Three patients also reported marked improvement in "off" state dystonia. One-year data are available on 12 patients who underwent evaluations according to the Core Assessment Program for Intracerebral Transplantation protocol preoperatively and at 3, 6, and 12 months after surgery. Significant improvements in Unified Parkinson's Disease Rating Scale sections II and III scores in the "off" state, composite "off" state scores of bradykinesia and rigidity, contralateral tremor in the "off" state, and contralateral dyskinesias were observed. Although there was reduction in the daily levodopa dose, this did not reach statistical significance. Major complications (15%) included hemiparesis (one of 20) and visual field cuts (two of 20); minor complications (45%) included mild cognitive dysfunction (four of 20), reading difficulty not related to visual disturbance (one of 20), and 5-10 lb weight gain (four of 20).

  3. Ozone over the Western Mediterranean Sea - results from two years of shipborne measurements

    NASA Astrophysics Data System (ADS)

    Velchev, K.; Cavalli, F.; Hjorth, J.; Marmer, E.; Vignati, E.; Dentener, F.; Raes, F.

    2011-01-01

    Ozone, along with other air pollutants, has been measured for two years from a monitoring station placed on a cruise ship that follows a regular track in the Western Mediterranean between April and October. Conditions favouring high ozone levels have been studied by analysis of weather maps and back trajectories. This analysis was focused on a transect over the open sea in the South Western Mediterranean between Tunis and Palma de Mallorca. High ozone levels were found in situations with an anticyclonic circulation over the Western Mediterranean when subsidence brings air masses down from altitudes between 1000 and 3500 m a.s.l. Analysis of composite meteorological maps suggests a relevant contribution of breeze circulation to subsidence during events with high surface ozone concentrations; this points to an important contribution from local ozone formation. A detailed back trajectory analysis of the origin of air masses with high ozone concentrations was carried out for two "hot spots" for ozone pollution, in the Gulf of Genoa and between Naples and Palermo, respectively. The main cause of high ozone levels in the Gulf of Genoa was found to be outflow from the Po Valley and the Genoa area while such episodes along the Naples-Palermo transect were most often associated with trajectories from the Rome or Naples areas. Analysis of the relationship between measured concentrations of Black Carbon and ozone allowed to evaluate the degree of photochemical "ageing" of the air masses encountered along the route of the cruise ship.

  4. Ozone over the Western Mediterranean Sea - results from two years of shipborne measurements

    NASA Astrophysics Data System (ADS)

    Velchev, K.; Cavalli, F.; Hjorth, J.; Marmer, E.; Vignati, E.; Dentener, F.; Raes, F.

    2010-03-01

    Ozone, along with other air pollutants, has been measured for two years from a monitoring station placed on a cruise ship that follows a regular track in the Western Mediterranean between April and October. Conditions favoring high ozone levels have been studied by analysis of weather maps and back trajectories. This analysis was focused on a transect over the open sea in the South Western Mediterranean between Tunis and Palma de Mallorca. High ozone levels were found in situations with an anticyclonic circulation over the Western Mediterranean when subsidence brings air masses down from altitudes between 1000 and 3500 m a.s.l. Analysis of composite meteorological maps suggest a relevant contribution of breeze circulation to subsidence during events with high surface ozone concentrations; this points to an important contribution from local ozone formation. A detailed back trajectory analysis of the origin of air masses with high ozone concentrations was carried out for two "hot spots" for ozone pollution, found along the coast south of Genova and between Napoli and Palermo, respectively. While it was found that the influence of plumes from areas with high pollutant levels might explain most episodes in the Northwestern transect, such "local" influences appeared to be of minor importance within the Napoli-Palermo transect.

  5. MACHO project 2nd year LMC microlensing results and dark matter implications

    SciTech Connect

    Alcock, C.; Allsman, R.A.; Alves, D.

    1996-02-01

    The MACHO Project is searching for galactic dark matter in the form of massive compact halo objects (Machos). Millions of stars in the Large Magellanic Cloud (LMC), Small Magellanic Cloud (SMC), and Galactic bulge are photometrically monitored in an attempt to detect rare gravitational microlensing events caused by otherwise invisible Machos. Analysis of two years of photometry on 8.5 million stars in the LMC reveals 8 candidate microlensing events, far more than the one event expected from lensing by low-mass stars in known galactic populations. Five these eight events we estimate the optical depth towards the LMC from events with 2 < i < 200 days to be r2 280 about 2.9+1 4/-0.8 X 10-7. This exceeds the optical depth of 0.5 x 10-7 expected for known stars and is to be compared with an optical depth of 4.7 X 10-7 predicted for a `standard` halo composed entirely of Machos. The total mass in this lensing population is 2 +1.2/-0.7 x 10+11 Mo (within 50 kpc from the Galactic center). Event timescales yield a most probable Macho Mass of 0.5 +0.3/-0.2 Mo, although this value is quite model dependent. -0.2

  6. Keratin Durability Has Implications for the Fossil Record: Results from a 10 Year Feather Degradation Experiment.

    PubMed

    Moyer, Alison E; Zheng, Wenxia; Schweitzer, Mary H

    2016-01-01

    Keratinous 'soft tissue' structures (i.e. epidermally derived and originally non-biomineralized), include feathers, skin, claws, beaks, and hair. Despite their relatively common occurrence in the fossil record (second only to bone and teeth), few studies have addressed natural degradation processes that must occur in all organic material, including those keratinous structures that are incorporated into the rock record as fossils. Because feathers have high preservation potential and strong phylogenetic signal, in the current study we examine feathers subjected to different burial environments for a duration of ~10 years, using transmission electron microscopy (TEM) and in situ immunofluorescence (IF). We use morphology and persistence of specific immunoreactivity as indicators of preservation at the molecular and microstructural levels. We show that feather keratin is durable, demonstrates structural and microstructural integrity, and retains epitopes suitable for specific antibody recognition in even the harshest conditions. These data support the hypothesis that keratin antibody reactivity can be used to identify the nature and composition of epidermal structures in the rock record, and to address evolutionary questions by distinguishing between alpha- (widely distributed) and beta- (limited to sauropsids) keratin.

  7. Keratin Durability Has Implications for the Fossil Record: Results from a 10 Year Feather Degradation Experiment

    PubMed Central

    Moyer, Alison E.; Zheng, Wenxia; Schweitzer, Mary H.

    2016-01-01

    Keratinous ‘soft tissue’ structures (i.e. epidermally derived and originally non-biomineralized), include feathers, skin, claws, beaks, and hair. Despite their relatively common occurrence in the fossil record (second only to bone and teeth), few studies have addressed natural degradation processes that must occur in all organic material, including those keratinous structures that are incorporated into the rock record as fossils. Because feathers have high preservation potential and strong phylogenetic signal, in the current study we examine feathers subjected to different burial environments for a duration of ~10 years, using transmission electron microscopy (TEM) and in situ immunofluorescence (IF). We use morphology and persistence of specific immunoreactivity as indicators of preservation at the molecular and microstructural levels. We show that feather keratin is durable, demonstrates structural and microstructural integrity, and retains epitopes suitable for specific antibody recognition in even the harshest conditions. These data support the hypothesis that keratin antibody reactivity can be used to identify the nature and composition of epidermal structures in the rock record, and to address evolutionary questions by distinguishing between alpha- (widely distributed) and beta- (limited to sauropsids) keratin. PMID:27384819

  8. The Atmospheric Lifetime Experiment. VI - Results for carbon tetrachloride based on 3 years data

    NASA Astrophysics Data System (ADS)

    Simmonds, P. G.; Alyea, F. N.; Cardelino, C. A.; Cunnold, D. M.; Crawford, A. J.; Rasmussen, R. A.; Lane, B. C.; Lovelock, J. E.; Prinn, R. G.

    1983-10-01

    The automated electron capture gas chromatographic determination of the atmospheric concentrations of CCl4 are reported for the period July 1978 to June 1981 at five coastal monitoring stations, Adrigole (Ireland), Cape Meares (Oregon), Ragged Point (Barbados, West Indies), Point Matatula (American Samoa), and Cape Grim (Tasmania). Daily measurements at approximately 6-hourly intervals are always complemented by an equivalent number of on-site calibration measurements. Estimates of CCl4 emissions to the atmosphere from known industrial sources are compared with the measured trends and the absolute values of the observed concentrations. A globally averaged atmospheric lifetime for CCl4 is calculated by using an optimal estimation technique incorporating a nine-box model of the atmosphere. The average global concentration of CCl4 from July 1978 to June 1981 in the lower troposphere was 118 pptv, and it was increasing 2.1 pptv/year over this period. Both the absolute concentration observed and its trend are consistent with the calculated releases of CCl4 and its expected destruction by stratospheric photolysis.

  9. Ablation for atrial fibrillation during mitral valve surgery: 1-year results through continuous subcutaneous monitoring.

    PubMed

    Bogachev-Prokophiev, Alexandr; Zheleznev, Sergey; Romanov, Alexander; Pokushalov, Evgeny; Pivkin, Alexey; Corbucci, Giorgio; Karaskov, Alexander

    2012-07-01

    Continuous monitoring of cardiac rhythm may play an important role in measuring the true symptomatic/asymptomatic atrial fibrillation (AF) burden and improve the management of anti-arrhythmic and anti-thrombotic therapies. Forty-seven patients with mitral valve disease and longstanding persistent AF (LSPAF) underwent a left atrial maze procedure with bipolar radiofrequency and valve surgery. The follow-up data recorded by an implanted loop recorder were analysed after 3, 6 and 12 months. On discharge, 40 (85.1%) patients were in stable sinus rhythm, as documented by in-office electrocardiography (ECG), 4 (8.5%) were in pacemaker rhythm and 3 (6.4%) were in AF. One (2.1%) patient died after 7 months. On 12-month follow-up examination, 30 (65.2%) patients had an AF burden <0.5% and were classified as responders. Three (6.5%) of the 16 non-responders had atrial flutter and 13 (27.7%) had documented AF recurrences with an AF burden >0.5%. Two (4.3%) patients with AF recurrences were completely asymptomatic. Among the symptomatic events stored by the patients, only 27.6% was confirmed as genuine AF recurrences according to the concomitant ECG recorded by the implanted loop recorder. A concomitant bipolar maze procedure during mitral valve surgery is effective in treating AF, as proved by detailed 1-year continuous monitoring.

  10. Ablation for atrial fibrillation during mitral valve surgery: 1-year results through continuous subcutaneous monitoring†

    PubMed Central

    Bogachev-Prokophiev, Alexandr; Zheleznev, Sergey; Romanov, Alexander; Pokushalov, Evgeny; Pivkin, Alexey; Corbucci, Giorgio; Karaskov, Alexander

    2012-01-01

    Continuous monitoring of cardiac rhythm may play an important role in measuring the true symptomatic/asymptomatic atrial fibrillation (AF) burden and improve the management of anti-arrhythmic and anti-thrombotic therapies. Forty-seven patients with mitral valve disease and longstanding persistent AF (LSPAF) underwent a left atrial maze procedure with bipolar radiofrequency and valve surgery. The follow-up data recorded by an implanted loop recorder were analysed after 3, 6 and 12 months. On discharge, 40 (85.1%) patients were in stable sinus rhythm, as documented by in-office electrocardiography (ECG), 4 (8.5%) were in pacemaker rhythm and 3 (6.4%) were in AF. One (2.1%) patient died after 7 months. On 12-month follow-up examination, 30 (65.2%) patients had an AF burden <0.5% and were classified as responders. Three (6.5%) of the 16 non-responders had atrial flutter and 13 (27.7%) had documented AF recurrences with an AF burden >0.5%. Two (4.3%) patients with AF recurrences were completely asymptomatic. Among the symptomatic events stored by the patients, only 27.6% was confirmed as genuine AF recurrences according to the concomitant ECG recorded by the implanted loop recorder. A concomitant bipolar maze procedure during mitral valve surgery is effective in treating AF, as proved by detailed 1-year continuous monitoring. PMID:22514258

  11. [Development of Human Health Discoveries. 10 years results of Young Innovative Company incubation].

    PubMed

    Marsac, Jean

    2014-01-01

    Medicine is evolving every day in its operating procedures and the services offered to patients, emphasizing personalized medicine, safety and medical benefits. The individual patient is more than ever the hub of healthcare organization. Medical innovation is thus a public health priority. However it requires an accurate assessment of medical utility and risk-benefit ratios, and in-depth analysis of economic and organizational impacts. Ten years of experience in the Paris Biotech Santé company incubator has identified key actions for effective support of research projects and the success of innovative companies. Strong expertise is needed to prepare development plans, ensure compliance with regulatory requirements and obtain research funding. During its first decade, this incubator has created 87 innovative companies employing 1500 people, raised more than 90 million euros of funding, and reached a cumulative company value of 1200 million euros. Key factors of success have been identified, but an analysis of the causes of failure shows that operational adjustments are mandatory, particularly a strong commitment from medical experts, in order to promote access to new and useful products for patients while at the same time assessing their social impact.

  12. Five-Year ALARA Review of Dosimetry Results 1 January 2009 through 31 December 2013.

    SciTech Connect

    Paulus, Luke R

    2014-08-01

    A review of dosimetry results from 1 January 2009 through 31 December 2013 was conducted to demonstrate that radiation protection methods used are compliant with regulatory limits and conform to the ALARA philosophy. This included a review and evaluation of personnel dosimetry (external and internal) results at Sandia National Laboratories, New Mexico as well as at Sandia National Laboratories, California. Additionally, results of environmental monitoring efforts at Sandia National Laboratories, New Mexico were reviewed. ALARA is a philosophical approach to radiation protection by managing and controlling radiation exposures (individual and collective) to the work force and to the general public to levels that are As Low As is Reasonably Achievable taking social, technical, economic, practical, and public policy considerations into account. ALARA is not a dose limit but a process which has the objective of attaining doses as far below applicable dose limits As Low As is Reasonably Achievable.

  13. Five-Year ALARA Review of Dosimetry Results 1 January 2010 through 31 December 2014.

    SciTech Connect

    Paulus, Luke R.

    2015-06-01

    A review of dosimetry results from 1 January 2010 through 31 December 2014 was conducted to demonstrate that radiation protection methods used are compliant with regulatory limits and conform to the philosophy to keep exposures to radiation As Low As is Reasonably Achievable (ALARA). This included a review and evaluation of personnel dosimetry (external and internal) results at Sandia National Laboratories, New Mexico as well as at Sandia National Laboratories, California. Additionally, results of environmental monitoring efforts at Sandia National Laboratories, New Mexico were reviewed. ALARA is a philosophical approach to radiation protection by managing and controlling radiation exposures (individual and collective) to the work force and to the general public to levels that are As Low As is Reasonably Achievable taking social, technical, economic, practical, and public policy considerations into account. ALARA is not a dose limit but a process which has the objective of attaining doses as far below applicable dose limits As Low As is Reasonably Achievable.

  14. [Analysis of the results of the SEIMC External Quality Control Program. Year 2008].

    PubMed

    Serrano, María del Remedio Guna; Mira, Nieves Orta; de Gopegui, Enrique Ruiz; Ovies, María Rosario; Cardona, Concepción Gimeno; Pérez, José L

    2010-01-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria and virology. This article present the most relevant conclusions and lessons from the 2008 controls. As a whole, the results obtained in 2008 confirm the excellent skill and good technical standards of the microbiology laboratories in Spain found in previous editions. However, a few deviations can be obtained in any laboratory, even in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal an external controls in order to assure the maximal quality of the microbiological tests.

  15. Final-Year Results from the i3 Scale-Up of Reading Recovery

    ERIC Educational Resources Information Center

    May, Henry; Sirinides, Philip; Gray, Abby; Davila, Heather Goldsworthy; Sam, Cecile; Blalock, Toscha; Blackman, Horatio; Anderson-Clark, Helen; Schiera, Andrew J.

    2015-01-01

    As part of the 2010 economic stimulus, a $55 million "Investing in Innovation" (i3) grant from the US Department of Education was awarded to scale up Reading Recovery across the nation. This paper presents the final round of results from the large-scale, mixed methods randomized evaluation of the implementation and impacts of Reading…

  16. Eight Years of Specialist Training of Dutch Intellectual Disability Physicians: Results of Scientific Research Education

    ERIC Educational Resources Information Center

    Evenhuis, Heleen M.; Penning, Corine

    2009-01-01

    Training in scientific research methods and skills is a vital part of Dutch specialist training in intellectual disability medicine. The authors evaluated results of such training at one Dutch university medical facility that had an obligatory research program involving projects conducted by the physicians-in-training (topics, teamwork, acquired…

  17. Staying on Course: Three-Year Results of the National Guard Youth ChalleNGe Evaluation

    ERIC Educational Resources Information Center

    Millenky, Megan; Bloom, Dan; Muller-Ravett, Sara; Broadus, Joseph

    2011-01-01

    High school dropouts face an uphill battle in a labor market that increasingly rewards skills and postsecondary credentials: they are more likely than their peers to need public assistance, be arrested or incarcerated, and less likely to marry. This report presents results from a rigorous evaluation of the National Guard Youth ChalleNGe Program,…

  18. A 10-Year Mechatronics Curriculum Development Initiative: Relevance, Content, and Results--Part I

    ERIC Educational Resources Information Center

    Das, S.; Yost, S. A.; Krishnan, M.

    2010-01-01

    This paper describes the first phase of a Mechatronics Curriculum Development effort--the design of an "Introduction to Mechatronics" course, the infusion of mechatronics activities throughout the curriculum and in outreach activities, and assessment results. In addition, the relevance and impact of such a curriculum on the education of engineers…

  19. WHAT’S CAUSING TOXICITY IN SEDIMENTS? RESULTS OF 20 YEARS OF TOXICITY IDENTIFICATION AND EVALUATIONS

    EPA Science Inventory

    Sediment toxicity identification and evaluation (TIE) methods have been used for 20 yr to identify the causes of toxicity in sediments around the world. In the present study, the authors summarize and categorize results of 36 peer-reviewed TIE studies (67 sediments) into nonioni...

  20. Hedging and severity of pecan scab – a second year of results

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Pecan scab, caused by the plant pathogenic fungus Fusicladium effusum, is the major disease of pecan in Georgia and elsewhere in the region. There are several reasons for hedging, and some issues may arise as a result of the hedging management practice. One of those issues might be increased disease...

  1. Sixty years of interest in flow and transport theories: Sources of inspiration and a few results

    NASA Astrophysics Data System (ADS)

    Raats, Peter A. C.

    2016-04-01

    By choosing to major in soil physics at Wageningen now exactly 60 years ago, I could combine my interest in exact sciences with my experience of growing up on a farm. I never regretted that choice. In the first twenty years, I profited much from close contacts with members of the immediate post-WW II generation of soil physicists (especially Jerry Bolt, Arnold Klute, Ed Miller, Champ Tanner, Wilford Gardner, John Philip, and Jan van Schilfgaarde), chemical engineers (especially at UW Madison the trio Bob Bird, Warren Stewart and Ed Lightfoot) and experts in continuum mechanics (especially at Johns Hopkins Clifford Truesdell and Jerald Ericksen). As graduate student at Illinois with Klute, to describe flow and transport theories in soil science I initially explored as possible framework thermodynamics of irreversible processes (TIP), but soon switched to the continuum theory of mixtures (CTM), initiated by Truesdell in 1957. In CTM, the balance of forces gave a rational basis for flux equations. CTM allowed me to deal with swelling/shrinkage, role of inertia, boundary conditions, and structured soils. Later, I did use TIP to deal with certain aspects of transfer of water and heat in soils and selective uptake of water and nutrients by plant roots. Recently, a variety of theories for upscaling from the pore scale to the Darcy scale have clarified the potential, limits and common ground of CTM and TIP. A great advantage of CTM is that it provides geometric tools suited for kinematic aspects of flow, transport, and growth/decay processes. In particular, the concept of material coordinates of the solid phase that I used in my PhD thesis to cope with large deformation due to swelling/shrinkage of soils, later also turned to be useful to deal with simultaneous shrinkage and decay in peat soils and compost heaps, and the growth of plant tissues. Also, by focusing on the material coordinates for the water, it became possible to describe transport of solutes in unsaturated

  2. Groundwater monitoring at three Oak Ridge National Laboratory inactive waste impoundments: results after one year

    SciTech Connect

    Francis, C. W.; Stansfield, R. G.

    1986-10-01

    To determine if the migration of potential contaminants from three inactive waste impoundments at Oak Ridge National Laboratory poses a threat to groundwater quality, at least one upgradient groundwater monitoring well and threee downgradient monitoring wells were installed at each impoundment in early 1985. These three unlined impoundments, formerly used to collect and, in some instances, treat wastewater are: the 3513 impoundment; the Old Hydrofracture Facility (OHF) impoundment; and the Homogeneous Reactor Experimnt No. 2 impoundment. Groundwater samples were collected quarterly for one year. Analyses were conducted for the groundwater protection parameters promulgated by the Resource Conservation and Recovery Act. The groundwater samples were also analyzed for polychlorinated biphenyls, copper, nickel, zinc, /sup 90/Sr, /sup 137/Cs, and tritium. The contaminants found most often to affect groundwater quality at all three waste impoundments were radionuclides. For example, mean concentrations of gross beta and gross alpha activity exceeded drinking water limits at all three sites. The gross beta limit was exceeded at the 3513 and OHF impoundments by either /sup 90/Sr or tritium levels. At the 3513 impoundment, there was substantial evidence that the downgradient groundwater has been contaminated by chromium and lead and possibly by halogenated organic compounds. At the OHF impoundment, the mean level of tritium measured in the upgradient well (about 91,000 Bq/L as compared with 80,000 Bq/L in the downgradient wells) indicated that the groundwater quality has been affected by the radioactive wastes buried in the low-level radioactive waste burial ground solid waste storage area-5 upgradient of the impoundment. Testing for groundwater contamination, disclosed statistically significant contamination at all three sites.

  3. One year clinical outcomes of renal artery stenting: the results of ODORI Registry.

    PubMed

    Sapoval, M; Tamari, I; Goffette, P; Downes, M; Senechal, Q; Fanelli, F; Reimer, P; Negaiwi, Z; De Cassin, P; Heye, S; Korobov, V; Tsetis, D; Abada, H

    2010-06-01

    The safety, efficacy and long term clinical benefits of renal artery revascularization by stenting are still a matter of debate. The aim of our study was to define the safety and efficacy of renal artery stenting with the Tsunami peripheral stent (Terumo Corporation, Tokyo, Japan). The ODORI was a prospective, multicentre registry which enrolled 251 consecutive patients, (276 renal arteries) in 36 centres across Europe. The primary endpoint was acute procedural success defined as <30% residual stenosis after stent placement. Secondary endpoints included major adverse events, blood pressure control, serum creatinine level, and target lesion revascularization (TLR) at 6 and 12 months. Patients were 70 +/- 10 years old, 59% were male, 33% had diabetes, and 96% hypertension. The main indications for renal stent implantation were hypertension in 83% and renal salvage in 39%. Direct stent implantation was performed in 76% of the cases. Acute success rate was 100% with residual stenosis of 2.5 +/- 5.4%. Systolic/diastolic blood pressure decreased from a mean of 171/89 at baseline to 142/78 mmHg at 6 months (p < 0.0001 vs. baseline), and 141/80 mmHg at 12 months (p < 0.0001 vs. baseline). Mean serum creatinine concentration did not change significantly in the total population. However, there was significant improvement in the highest tercile (from 283 micromol/l at baseline to 205 and 209 micromol/l at 6 and 12 months respectively). At 12-months, rates of restenosis and TLR were 6.6 and 0.8% respectively. The 12 month cumulative rate of all major clinical adverse events was 6.4% while the rate of device or procedure related events was 2.4%. In hypertensive patients with atherosclerotic renal artery stenosis Tsunami peripheral balloon-expandable stent provides a safe revascularization strategy, with a potential beneficial impact on hypertension control and renal function in the highest risk patients.

  4. One Year Clinical Outcomes of Renal Artery Stenting: The Results of ODORI Registry

    SciTech Connect

    Sapoval, M.; Tamari, I.; Goffette, P.; Downes, M.; Senechal, Q.; Fanelli, F.; Reimer, P.; Negaiwi, Z.; Cassin, P. De; Heye, S.; Korobov, V.; Tsetis, D.; Abada, H.

    2010-06-15

    The safety, efficacy and long term clinical benefits of renal artery revascularization by stenting are still a matter of debate. The aim of our study was to define the safety and efficacy of renal artery stenting with the Tsunami peripheral stent (Terumo Corporation, Tokyo, Japan). The ODORI was a prospective, multicentre registry which enrolled 251 consecutive patients, (276 renal arteries) in 36 centres across Europe. The primary endpoint was acute procedural success defined as <30% residual stenosis after stent placement. Secondary endpoints included major adverse events, blood pressure control, serum creatinine level, and target lesion revascularization (TLR) at 6 and 12 months. Patients were 70 {+-} 10 years old, 59% were male, 33% had diabetes, and 96% hypertension. The main indications for renal stent implantation were hypertension in 83% and renal salvage in 39%. Direct stent implantation was performed in 76% of the cases. Acute success rate was 100% with residual stenosis of 2.5 {+-} 5.4%. Systolic/diastolic blood pressure decreased from a mean of 171/89 at baseline to 142/78 mmHg at 6 months (p < 0.0001 vs. baseline), and 141/80 mmHg at 12 months (p < 0.0001 vs. baseline). Mean serum creatinine concentration did not change significantly in the total population. However, there was significant improvement in the highest tercile (from 283 {mu}mol/l at baseline to 205 and 209 {mu}mol/l at 6 and 12 months respectively). At 12-months, rates of restenosis and TLR were 6.6 and 0.8% respectively. The 12 month cumulative rate of all major clinical adverse events was 6.4% while the rate of device or procedure related events was 2.4%. In hypertensive patients with atherosclerotic renal artery stenosis Tsunami peripheral balloon-expandable stent provides a safe revascularization strategy, with a potential beneficial impact on hypertension control and renal function in the highest risk patients.

  5. Selective laser trabeculoplasty (SLT): 1-year results in early and advanced open angle glaucoma.

    PubMed

    Schlote, Torsten; Kynigopoulos, Myron

    2016-02-01

    The purpose of this study was to examine the efficacy of selective laser trabeculoplasty (SLT) in eyes with early and more advanced stages of open angle glaucoma within 1 year of follow-up. Retrospective chart review in a consecutive series of patients treated by SLT to reduce intraocular pressure (IOP) or decrease number of topical medications in cases of discomfort and allergy. The cup-to-disc ratio of the optic nerve and the GSS 2 (glaucoma staging system 2) was used to differentiate between early (group 1) and more advanced (group 2) stages of glaucoma. At the time of SLT treatment, no new signs of glaucoma progression were seen. Only the first treated eye of every patient was included in the analysis. In group 1 (early glaucoma), 27 eyes were included. IOP reduction <21 mmHg/>20 % of the preoperative IOP-value and reduction of medication were achieved in 17 eyes (62.96 %). Successful re-treatment was necessary in 2 eyes (7.4 %). In group 2 (advanced glaucoma), 44 eyes underwent SLT. In eight eyes (18.18 %), filtrating surgery was necessary after initial SLT. In the remaining 36 eyes, IOP reduction <21 mmHg/>20 % of the baseline IOP was achieved in 26 eyes (59.09 % of 44 eyes) and IOP reduction <18 mmHg/> 30 % of the baseline IOP in 22 eyes (50 % of 44 eyes). SLT was safe and effective in nearly 2/3 of early glaucoma patients and also in 50 % of advanced glaucoma patients using stronger criteria of success. Failure of SLT in advanced glaucoma should lead to immediate filtrating surgery, which seems not to be associated with higher risk of fibrosis.

  6. Variability of Ionosphere over Africa: Results from International Heliophysical Year IHY

    NASA Astrophysics Data System (ADS)

    Rabiu, Babatunde

    Space Environment Research Centre of Kyushu University, Japan, installed 13 units of Magnetic Data Acquisition Systems MAGDAS over Africa during the International Heliophysical Year IHY. Institute for Scientific Research Bolton College USA in collaboration with the Aeronomy and Radiopropagation Laboratory of International Centre for Theoretical Physics, Italy, has jointly placed over 15 units of GPS systems over Africa suitable for total electron content TEC and ionospheric scintillation studies. Magnetic records from 10 stations along the African 96o Magnetic Meridian (Geographical 30o -40o East) were examined for Solar quiet daily Sq variation due in the three geomagnetic field components H, D and Z. Latitudinal variations of Sq in the geomagnetic components were examined. Signatures of equatorial electrojet and worldwide Sq were identified and studied in detail. H field experienced more variation within the equatorial electrojet zone. Diurnal and seasonal variations of the geomagnetic variations in the three components were discussed. Levels of inter-relationships between the Sq and its variability in the three components were statistically derived and interpreted in line with the mechanisms responsible for the variations of the geomagnetic field. Data from 2 magnetic observatories within equatorial electrojet EEJ strip and 2 stations outside the EEJ strip were employed to evaluate and study the signatures of the Equatorial electrojet over the African sector. The transient variations of the EEJ at two almost parallel axes using Lagos-Ilorin and Nairobi-Addis pairs were examined. The EEJ appear stronger in East than West Africa. The magnitudes and patterns of variation of EEJ strength along the two axes were examined for any simultaneity or otherwise of responses to ionospheric processes. The flow gradient of EEJ along the African sector was estimated and its diurnal variation studied. Complementarily data from GPS was used to study diurnal and seasonal

  7. Observables sensitive to absolute neutrino masses: A reappraisal after WMAP 3-year and first MINOS results

    SciTech Connect

    Fogli, G. L.; Lisi, E.; Marrone, A.; Melchiorri, A.; Serra, P.; Palazzo, A.; Silk, J.; Slosar, A.

    2007-03-01

    In the light of recent neutrino oscillation and nonoscillation data, we revisit the phenomenological constraints applicable to three observables sensitive to absolute neutrino masses: The effective neutrino mass in single beta decay (m{sub {beta}}); the effective Majorana neutrino mass in neutrinoless double beta decay (m{sub {beta}}{sub {beta}}); and the sum of neutrino masses in cosmology ({sigma}). In particular, we include the constraints coming from the first Main Injector Neutrino Oscillation Search (MINOS) data and from the Wilkinson Microwave Anisotropy Probe (WMAP) three-year (3y) data, as well as other relevant cosmological data and priors. We find that the largest neutrino squared mass difference is determined with a 15% accuracy (at 2{sigma}) after adding MINOS to world data. We also find upper bounds on the sum of neutrino masses {sigma} ranging from {approx}2 eV (WMAP-3y data only) to {approx}0.2 eV (all cosmological data) at 2{sigma}, in agreement with previous studies. In addition, we discuss the connection of such bounds with those placed on the matter power spectrum normalization parameter {sigma}{sub 8}. We show how the partial degeneracy between {sigma} and {sigma}{sub 8} in WMAP-3y data is broken by adding further cosmological data, and how the overall preference of such data for relatively high values of {sigma}{sub 8} pushes the upper bound of {sigma} in the sub-eV range. Finally, for various combination of data sets, we revisit the (in)compatibility between current {sigma} and m{sub {beta}}{sub {beta}} constraints (and claims), and derive quantitative predictions for future single and double beta decay experiments.

  8. Yucca mountain project getter program results(year 1):I-129 and other anions of concern.

    SciTech Connect

    Krumhansl, James Lee; Pless, Jason; Chwirka, J. Benjamin

    2006-07-01

    Although high level nuclear wastes (HLW) contain a daunting array of radioisotopes, only a restricted number are long-lived enough to be problematic, and of these many are either effectively insoluble or are likely to be scavenged from solution by minerals indigenous to all aquifers. Those few constituents likely to travel significant distances through aquifers either form colloids (and travel as particulates) or anions--which are not sorbed onto the predominantly negatively charged mineral surfaces. Iodine ({sup 129}I) is one such constituent and may travel as either iodide (I{sup -}) or iodate (IO{sub 3}{sup -}) depending on whether conditions are mildly reducing or oxidizing. Conventionally, {sup 99}Tc (traveling as TcO{sub 4}{sup -}) is regarded as being of greater concern since it is both more abundant and has a shorter half life (e.g., has a higher specific activity). However, it is unclear whether TcO{sub 4}{sup -} will ever actually form in the mildly reducing environments thought likely within degrading HLW canisters. Instead, technetium may remain reduced as highly insoluble Tc(IV), in which case {sup 129}I might become a significant risk driver in performance assessment (PA) calculations. In the 2004-2005 time frame the US Department of Energy (DOE)--Office of Civilian Radioactive Waste Management (OCRUM), Office of Science and Technology International (S&T) funded a program to identify ''getters'' for possible placement in the invert beneath HLW packages in the repository being planned by the Yucca Mountain Project (YMP). This document reports on progress made during the first (and only) year of this activity. The problem is not a new one and the project did not proceed in a complete vacuum of information. Potential leads came from past studies directed at developing anion getters for a near surface low-level waste facility at Hanford, which suggested that both copper-containing compounds and hydrotalcite-group minerals might be promising. Later work

  9. Monteggia-like lesions – treatment strategies and one-year results

    PubMed Central

    Laun, Reinhold; Wild, Michael; Brosius, Lars; Hakimi, Mohssen

    2015-01-01

    Introduction: The eponym “Monteggia fracture” includes various patterns of complex fracture-dislocations of the proximal ulna and radius, which are not well defined yet. They are frequently described as Monteggia-like lesions or Monteggia equivalent injuries. Until today, these injury patterns have been reported rarely. The objective of this retrospective study was to better define patterns of injury and to document the short-term results of treatment with current fixation techniques. Methods: Ten patients with a Monteggia-like lesion were included in this study and clinical and radiological follow-up examinations at an average of 12.3 months after the trauma were performed. For clinical follow-up the Mayo Modified Wrist Score, the Mayo Elbow Performance Score, the functional rating index of Broberg and Morrey, and the DASH score were utilized. Results: Osteosynthesis of the ulna was performed using a proximally contoured or precontoured LCP (locking compression plate) in all patients. All patients had a fracture of the radial head. All patients with a Mason type III radial head fracture received a cemented bipolar radial head prosthesis. All Mason type II fractures were treated with open reduction and internal fixation using mini screws. In all Mason type I fractures the treatment of the radial head dislocation was by closed reduction. Associated coronoid fractures were stabilized with lag screws through the ulnar plate or with independent lag screws after reduction of the fracture. According to the aforementioned scoring systems good to excellent results could be achieved. Conclusions: Our findings demonstrate that good or excellent short-term results can be obtained if the injury is classified correctly and a standardized surgical treatment of all components of the injury is achieved. Further studies with larger patient populations and longer follow up periods are needed to evaluate long-term effectiveness of this treatment concept. PMID:26734535

  10. 2014 Survivor Experience Survey: Report on Preliminary Results. Fiscal Year 2014, Quarter 4

    DTIC Science & Technology

    2014-12-01

    sexual assault. The Survivor Experience Survey (SES) is the first DoD-wide survey effort designed to assess the use and effectiveness of the...the DoD’s sexual assault prevention and response programs are working effectively . iv for any form of sexual assault, and made their report at...Results from DMDC’s 2012 Workplace and Gender Relations Survey of Active Duty Members indicated some respondents did not want to report their sexual

  11. Outstanding results from one year's activities of the ESA Metric Camera Working Group

    NASA Astrophysics Data System (ADS)

    Togliatti, G.

    1985-06-01

    Results of the Spacelab Metric Camera experiment on STS-9 in photogrammetry: (precision, triangulations, point identification and mapping, orthophotos); thematic interpretations; and geological interpretation are summarized. Performance is fairly satisfactory in topographic mapping and in geological and thematic applications, with shortcomings in features identification, mainly due to poor lighting conditions and absence of image motion compensation. The metric accuracy of the images is very good, and in several cases better than expected.

  12. How to Interpret Thyroid Biopsy Results: A Three-Year Retrospective Interventional Radiology Experience

    SciTech Connect

    Oppenheimer, Jason D. Kasuganti, Deepa; Nayar, Ritu; Chrisman, Howard B.; Lewandowski, Robert J.; Nemcek, Albert A.; Ryu, Robert K.

    2010-08-15

    Results of thyroid biopsy determine whether thyroid nodule resection is appropriate and the extent of thyroid surgery. At our institution we use 20/22-gauge core biopsy (CBx) in conjunction with fine-needle aspiration (FNA) to decrease the number of passes and improve adequacy. Occasionally, both ultrasound (US)-guided FNA and CBx yield unsatisfactory specimens. To justify clinical recommendations for these unsatisfactory thyroid biopsies, we compare rates of malignancy at surgical resection for unsatisfactory biopsy results against definitive biopsy results. We retrospectively reviewed a database of 1979 patients who had a total of 2677 FNA and 663 CBx performed by experienced interventional radiologists under US guidance from 2003 to 2006 at a tertiary-care academic center. In 451 patients who had surgery following biopsy, Fisher's exact test was used to compare surgical malignancy rates between unsatisfactory and malignant biopsy cohorts as well as between unsatisfactory and benign biopsy cohorts. We defined statistical significance at P = 0.05. We reported an overall unsatisfactory thyroid biopsy rate of 3.7% (100/2677). A statistically significant higher rate of surgically proven malignancies was found in malignant biopsy patients compared to unsatisfactory biopsy patients (P = 0.0001). The incidence of surgically proven malignancy in unsatisfactory biopsy patients was not significantly different from that in benign biopsy patients (P = 0.8625). In conclusion, an extremely low incidence of malignancy was associated with both benign and unsatisfactory thyroid biopsy results. The difference in incidence between these two groups was not statistically significant. Therefore, patients with unsatisfactory biopsy specimens can be reassured and counseled accordingly.

  13. One Year Clinical Outcomes of Renal Artery Stenting: The Results of ODORI Registry

    PubMed Central

    Tamari, I.; Goffette, P.; Downes, M.; Senechal, Q.; Fanelli, F.; Reimer, P.; Negaiwi, Z.; De Cassin, P.; Heye, S.; Korobov, V.; Tsetis, D.; Abada, H.

    2009-01-01

    The safety, efficacy and long term clinical benefits of renal artery revascularization by stenting are still a matter of debate. The aim of our study was to define the safety and efficacy of renal artery stenting with the Tsunami peripheral stent (Terumo Corporation, Tokyo, Japan). The ODORI was a prospective, multicentre registry which enrolled 251 consecutive patients, (276 renal arteries) in 36 centres across Europe. The primary endpoint was acute procedural success defined as <30% residual stenosis after stent placement. Secondary endpoints included major adverse events, blood pressure control, serum creatinine level, and target lesion revascularization (TLR) at 6 and 12 months. Patients were 70 ± 10 years old, 59% were male, 33% had diabetes, and 96% hypertension. The main indications for renal stent implantation were hypertension in 83% and renal salvage in 39%. Direct stent implantation was performed in 76% of the cases. Acute success rate was 100% with residual stenosis of 2.5 ± 5.4%. Systolic/diastolic blood pressure decreased from a mean of 171/89 at baseline to 142/78 mmHg at 6 months (p < 0.0001 vs. baseline), and 141/80 mmHg at 12 months (p < 0.0001 vs. baseline). Mean serum creatinine concentration did not change significantly in the total population. However, there was significant improvement in the highest tercile (from 283 μmol/l at baseline to 205 and 209 μmol/l at 6 and 12 months respectively). At 12-months, rates of restenosis and TLR were 6.6 and 0.8% respectively. The 12 month cumulative rate of all major clinical adverse events was 6.4% while the rate of device or procedure related events was 2.4%. In hypertensive patients with atherosclerotic renal artery stenosis Tsunami peripheral balloon-expandable stent provides a safe revascularization strategy, with a potential beneficial impact on hypertension control and renal function in the highest risk patients. PMID:19908091

  14. A new 10,000 year pollen record from Lake Kinneret (Israel) - first results

    NASA Astrophysics Data System (ADS)

    Schiebel, V.; Litt, T.; Nowaczyk, N.; Stein, M.; Wennrich, V.

    2012-04-01

    Lake Kinneret - as part of the Jordan Rift Valley in Israel - is situated in the southern Levant, which is affected by Eastern Mediterranean climate. The present lake level is around 212 m below msl. Lake Kinneret has a surface of ca. 165 km2 and its watershed comprises the Galilee, the Golan Heights, the Hermon Range and the Anti-Lebanon Mountains. Its most important tributary is the Jordan River. The geography of the Lake Kinneret region is characterised by big differences in altitude. Steep slopes rise up to 560 m above the lake level in the west, north, and east. Mount Hermon (2814 m above mean sea level, amsl) is the highest summit of the Anti-Lebanon Range, and Mount Meron (1208 m amsl) located in the Upper Galilee encircle Lake Kinneret within a 100-km range in the northwest. Due to the pattern of average precipitation, distinct plant-geographical territories converge in the region: The Mediterranean and the Irano-Turanian biom (after Zohary). Varying ratios of characteristic pollen taxa representing certain plant associations serve as proxy data for the reconstruction of paleovegetation, paleoenvironment, and paleoclimate. We present a pollen record based on analyses of sediment cores obtained during a drilling campaign on Lake Kinneret in March 2010. A composite profile of 17.8 m length was established by correlating two parallel cores by using magnetic susceptibility data. Our record encompasses the past ca. 10,000 years of a region, which has been discussed as migration corridor of humans to Europe and, being part of the Fertile Crescent, as the cradle of agriculture in West Asia. Conclusions concerning human impact on vegetation and therefore population density can be drawn by analysing changes of ratios of certain plant taxa such as Olea europaea cultivated in this region since the Chalcolithic Period (6,500 BP). In addition, stable isotope data were produced from discrete bulk samples, and the elemental composition of the sediments was determined by

  15. Results from the first five years of radiation exposure monitoring aboard the ISS

    NASA Astrophysics Data System (ADS)

    Golightly, M.; Semones, E.; Shelfer, T.; Johnson, S.; Zapp, N.; Weyland, M.

    NASA uses a variety of radiation monitoring devices aboard the International Space Station as part of its space flight radiation health program. This operational monitoring system consists of passive dosimeters, internal and external charged particle telescopes, and a tissue equivalent proportional counter (TEPC). Sixteen passive dosimeters, each consisting of TLD-100, TLD-300, TLD-600, and TLD-700 chips in a small acrylic holder, are placed throughout the habitable volume of the ISS. The TEPC and internal charged particle telescopes are portable and can be relocated to multiple locations in the Lab Module or Service Module. The external charged particle telescopes are mounted to a fixed boom attached to the starboard truss. Passive dosimeters were used in eleven monitoring periods over the period 20 May 1999 to 04 May 2003. Over this period exposure rates from TLD-100 measurements ranged from 0.120-0.300 mGy/d. Exposure rates inside the habitable volume are non-uniform: exposures vary by a factor of ˜ 1.7 from minimum to maximum, with the greatest non-uniformity occurring in the Lab Module. Highest daily exposure rates are near the window in the Lab Module, inside the Joint Airlock, and the sleep stations inside the Service Module, while the lowest rates occur inside the polyethylene-lined Temporary Sleep Station in the Lab Module, adjacent to the port ``arm'' of Node 1, and the aft end of the Service Module. The minimum exposure rates as measured by the passive dosimeters occurred in the spring of 2002, very close to the solar F10.7 emission maximum (Feb 2002), and two years after the sunspot maximum (Apr 2000). Exposure rates have since gradually increased as the sun's activity transitions towards solar minimum conditions. Since 01 Jun 2002, dose rates measured by the IV-CPDS, estimated from the count rate in first detector of the telescope's stack, ranged from ˜ 0.170-0.390 mGy/d. The maximum measured dose rate occurred 28 Oct 2003 during the ``Halloween

  16. [Tropical monsoon forests of Vietnam (results of 20 years of phytoecological research)].

    PubMed

    Kuznetsov, A N; Kuznetsova, S P

    2013-01-01

    This study was carried out during the period 1989-2011. The following areas were included: Vietnam, Laos, Cambodia, Indonesia, and Malaysia. Climax tropical forest and anthropogenically transformed ecosystems, including those damaged by the chemical warfare program of the United States in Vietnam, were investigated. Some regularities in the structure dynamics and functioning of forests ecosystems under a tropical monsoon climate have been revealed. The principles of classification of tropical forests have been elaborated. The major results of investigation of the tropical monsoon forests in Vietnam are given.

  17. Inspection of Nickel Alloy Welds: Results from Five-Year International Program

    NASA Astrophysics Data System (ADS)

    Prokofiev, Iouri; Cumblidge, Stephen E.; Doctor, Steven R.

    2011-06-01

    The U.S. Nuclear Regulatory Commission established and coordinated the international Program for the Inspection of Nickel alloy Components (PINC). The goal of PINC was to evaluate the capabilities of various nondestructive examination (NDE) techniques to detect and characterize primary water stress corrosion cracking (PWSCC) in dissimilar metal welds. Round-robin results showed that a combination of conventional and phased-array ultrasound provide the highest performance for flaw detection and depth sizing in dissimilar metal piping welds. The effective detection of flaws in bottom-mounted instrumentation penetrations by eddy current and ultrasound shows that it may be possible to reliably inspect these components in the field.

  18. Inspection of Nickel Alloy Welds: Results from Five Year International Program

    SciTech Connect

    Prokofiev, Iouri; Cumblidge, Stephen E.; Doctor, Steven R.

    2011-06-23

    The U.S. Nuclear Regulatory Commission established and coordinated the international Program for the Inspection of Nickel alloy Components (PINC). The goal of PINC was to evaluate the capabilities of various nondestructive examination (NDE) techniques to detect and characterize primary water stress corrosion cracking (PWSCC) in dissimilar metal welds. Round-robin results showed that a combination of conventional and phased-array ultrasound provide the highest performance for flaw detection and depth sizing in dissimilar metal piping welds. The effective detection of flaws in bottom-mounted instrumentation penetrations by eddy current and ultrasound shows that it may be possible to reliably inspect these components in the field.

  19. Conservative surgery and radiotherapy for stage I/II breast cancer using lung density correction: 10-year and 15-year results

    SciTech Connect

    Pierce, Lori J. . E-mail: ljpierce@umich.edu; Griffith, Kent A.; Hayman, James A.; Douglas, Kathye R.; Lichter, Allen S.

    2005-04-01

    Purpose: Radiotherapy (RT) planning for breast cancer using lung density correction improves dose homogeneity. Its use obviates the need for a medial wedge, thus reducing scatter to the opposite breast. Although lung density correction is used at many centers in planning for early-stage breast cancer, long-term results of local control and survival have not been reported. Since 1984, we have used lung density correction for dose calculations at the University of Michigan. We now present our 10-year and 15-year results. Methods and Materials: The records of 867 patients with Stage I/II breast cancer treated with breast-conserving surgery and RT with or without systemic therapy were reviewed. Tangential fields delivering 45-50 Gy to the whole breast calculated using lung density correction were used. A boost was added in 96.8% of patients for a total median dose of 61.8 Gy. Results: With a median follow-up of 6.6 years (range, 0.2-18.9 years), 5-, 10-, and 15-year actuarial rates of in-breast tumor recurrence as only first failure were 2.2%, 3.6%, and 5.4%, respectively. With surgical salvage, the 15-year cumulative rate of local control was 99.7%. Factors that significantly predicted for increased rate of local recurrence in multivariate analysis were age {<=} 35 years, hazard ratio 4.8 (95% confidence interval [CI], 1.6-13.9) p = 0.004; negative progesterone receptor status, hazard ratio 6.8 (95% CI, 2.3-20.3) p = < 0.001; negative estrogen receptor status, hazard ratio 4.0 (95% CI, 1.5-11.1) p = 0.007; and lack of adjuvant tamoxifen therapy, hazard ratio 7.7 (95% CI, 1.7-33.3) p = 0.008. Relapse-free survival rates at 5, 10, and 15 years were 84.6%, 70.8%, and 55.9%, respectively; breast cancer-specific survival rates were 94.4%, 90.5%, and 86.9%, respectively; and corresponding estimates for overall survival were 89.7%, 75.7%, and 61.3%. Conclusions: Use of lung density correction was associated with high rates of local control, relapse-free survival, breast

  20. Interprofessional undergraduate clinical learning: results from a three year project in a Danish Interprofessional Training Unit.

    PubMed

    Jacobsen, Flemming; Fink, Anna Marie; Marcussen, Vibeke; Larsen, Kristian; Hansen, Torben Baek

    2009-01-01

    On entering higher education students become professionally socialized, and parallel with this, stereotyping takes place, students developing a more positive assessment of their own roles than those of other professions. This difference between the view of their own and other professions can contribute to creating cognitive and social boundaries between professions that hinder sharing of knowledge, which can result in poor cooperation. Interprofessional training can provide students with good clinical expertise in their own profession as well as teach them about other professions encouraging more positive attitudes between the professions. This project has taken place from 2004 to 2007 in a Danish Interprofessional Training Unit manned with students from the professions occupational therapy, physiotherapy, medicine and nursing. As part of an evaluation of the project, four focus group interviews and two in-depth interviews were analysed using the technique of Systematic Text Condensation. Results show that the goals of the Interprofessional Training Unit were fulfilled because the students learned interprofessional teamwork, strengthened their own professional role and worked together in an organization for the benefit of the patient. All this took place in a secure learning environment in which new methods of coordinating and integrating clinical and theoretical interprofessional learning were developed and tested.

  1. Building the European Seismological Research Infrastructure: results from 4 years NERIES EC project

    NASA Astrophysics Data System (ADS)

    van Eck, T.; Giardini, D.

    2010-12-01

    The EC Research Infrastructure (RI) project, Network of Research Infrastructures for European Seismology (NERIES), implemented a comprehensive European integrated RI for earthquake seismological data that is scalable and sustainable. NERIES opened a significant amount of additional seismological data, integrated different distributed data archives, implemented and produced advanced analysis tools and advanced software packages and tools. A single seismic data portal provides a single access point and overview for European seismological data available for the earth science research community. Additional data access tools and sites have been implemented to meet user and robustness requirements, notably those at the EMSC and ORFEUS. The datasets compiled in NERIES and available through the portal include among others: - The expanded Virtual European Broadband Seismic Network (VEBSN) with real-time access to more then 500 stations from > 53 observatories. This data is continuously monitored, quality controlled and archived in the European Integrated Distributed waveform Archive (EIDA). - A unique integration of acceleration datasets from seven networks in seven European or associated countries centrally accessible in a homogeneous format, thus forming the core comprehensive European acceleration database. Standardized parameter analysis and actual software are included in the database. - A Distributed Archive of Historical Earthquake Data (AHEAD) for research purposes, containing among others a comprehensive European Macroseismic Database and Earthquake Catalogue (1000 - 1963, M ≥5.8), including analysis tools. - Data from 3 one year OBS deployments at three sites, Atlantic, Ionian and Ligurian Sea within the general SEED format, thus creating the core integrated data base for ocean, sea and land based seismological observatories. Tools to facilitate analysis and data mining of the RI datasets are: - A comprehensive set of European seismological velocity reference

  2. First Year Wilkinson Microwave Anisotropy Probe (WMAP)Observations: Preliminary Maps and Basic Results

    NASA Technical Reports Server (NTRS)

    Bennett, C. L.; Halpern, M.; Hinshaw, G.; Jarosik, N.; Kogut, A.; Limon, M.; Meyer, S. S.; Page, L.; Spergel, D. N.; Tucker, G. S.

    2003-01-01

    We present full sky microwave maps in five frequency bands (23 to 94 GHz) from the WMAP first year sky survey. Calibration errors are less than 0.5% and the low systematic error level is well specified. The cosmic microwave background (CMB) is separated from the foregrounds using multifrequency data. The sky maps are consistent with the 7 in. full-width at half-maximum (FWHM) Cosmic Background Explorer (COBE) maps. We report more precise, but consistent, dipole and quadrupole values. The CMB anisotropy obeys Gaussian statistics with -58 less than f(sub NL) less than 134 (95% CL). The 2 less than or = l less than or = 900 anisotropy power spectrum is cosmic variance limited for l less than 354 with a signal-to-noise ratio greater than 1 per mode to l = 658. The temperature-polarization cross-power spectrum reveals both acoustic features and a large angle correlation from reionization. The optical depth of reionization is tau = 0.17 +/- 0.04, which implies a reionization epoch of t(sub r) = 180(sup +220, sub -80) Myr (95% CL) after the Big Bang at a redshift of z(sub r) = 20(sup +10, sub -9) (95% CL) for a range of ionization scenarios. This early reionization is incompatible with the presence of a significant warm dark matter density. A best-fit cosmological model to the CMB and other measures of large scale structure works remarkably well with only a few parameters. The age of the best-fit universe is t(sub 0) = 13.7 +/- 0.2 Gyr old. Decoupling was t(sub dec) = 379(sup +8, sub -7)kyr after the Big Bang at a redshift of z(sub dec) = 1089 +/- 1. The thickness of the decoupling surface was Delta(sub z(sub dec)) = 195 +/- 2. The matter density of the universe is Omega(sub m)h(sup 2) = 0.135(sup +0.008, sub -0.009) the baryon density is Omega(sub b)h(sup 2) = 0.0224 +/- 0.0009, and the total mass-energy of the universe is Omega(sub tot) = 1.02 +/- 0.02. There is progressively less fluctuation power on smaller scales, from WMAP to fine scale CMB measurements to galaxies

  3. Results of calendar year 1995 Well Inspection and Maintenance Program Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect

    McMaster, B.W.

    1996-07-01

    This document is a compendium of results of the 1995 Monitor Well Inspection and Maintenance Program at the US Department of Energy`s Oak Ridge Y-12 Plant. This report documents the work relating to well inspections and maintenance requests. Inspections are implemented in order to better assess the condition and maintenance needs of wells that are actively being monitored. Currently this approach calls for inspecting all wells on a routine (annual or triennial) basis which are: (1) in an active sampling program; (2) included in a hydrologic study; or (3) not in service, but not scheduled for plugging and abandonment. Routine inspections help to ensure that representative groundwater samples and hydrologic data are being collected, and contribute to the effective longevity of each well. This report formally presents well inspection and maintenance activities that were conducted at the Y-12 Plant from August through December 1995.

  4. New Activity of Chiron: Results from 5 Years of Photometric Monitoring

    NASA Astrophysics Data System (ADS)

    Duffard, René; Lazzaro, Daniela; Pinto, Sandro; Carvano, Jorge; Angeli, Claudia; Alvarez-Candal, Alvaro; Fernández, Silvia

    2002-11-01

    The results of photometric observations of Centaur object Chiron carried out at the Observatório do Pico dos Dias (OPD, Brazil), the Estación Astrofı´sica de Bosque Alegre (EABA, Argentina), and Complejo Astronómico El Leoncito (CASLEO, Argentina) from 1997 to 2001 are presented here. The analysis of the photometric data shows that the brightness of Chiron reached a minimum value in 1999 and began increasing again in 2000. The absolute magnitude, HV, varied from 7.26 in June 1999 to 5.78 in April 2001. The data tend to indicate that Chiron is starting a new outburst of activity which is compatible with a sporadic cometary behavior not related to heliocentric distance.

  5. Forty years after the first dark resonance experiment: an overview of the COSMA project results

    NASA Astrophysics Data System (ADS)

    Mariotti, E.; Bevilacqua, G.; Biancalana, V.; Cecchi, R.; Dancheva, Y.; Khanbekyan, Alen; Marinelli, C.; Moi, L.; Stiaccini, L.; Cartaleva, S.; Andreeva, C.; Alipieva, E.; Gateva, S.; Krasteva, A.; Slavov, D.; Taskova, E. T.; Taslakov, M.; Todorov, P.; Tsvetkov, S.; Wilson Gordon, A.; Margalit, L.; Gawlik, W.; Pustelny, S.; Stabrawa, A.; Sudyka, J.; Wojciechowski, A.; Renzoni, F.; Deans, C.; Hussain, S.; Marmugi, L.; Rassi, D.; Ozun, O.; Sarkisyan, D.; Azizbekyan, H.; Drampyan, R.; Khanbekyan, Alek.; Mirzoyan, R.; Papoyan, A.; Sargsyan, A.; Shmavonyan, S.; Tonoyan, A.; Ghosh, P. N.; Dey, S.; Mitra, S.; Ray, B.; Nasyrov, K. A.; Chapovsky, P.; Entin, V.; Nikolov, N.; Petrov, N.; Budker, D.; Patton, B.; Wickenbrock, A.; Zhivun, L.; Gozzini, S.

    2016-01-01

    COSMA: Coherent Optics Sensors for Medical Application is an European Marie Curie Project running from 2012 to March 2016, with the participation of 10 teams from Armenia, Bulgaria, India, Israel, Italy, Poland, Russia, UK, USA. The main objective was to focus theoretical and experimental research on biomagnetism phenomena, with the specific aim to develop all-optical sensors dedicated to their detection and suitable for applications in clinical diagnostics. The paper presents some of the most recent results obtained during the exchange visits of the involved scientists, after an introduction about the phenomenon which is the pillar of this kind of research and of many other new fields in laser spectroscopy, atomic physics, and quantum optics: the dark resonance.

  6. Screening of thalassaemia carriers in intermediate school of Latium: results of four years' work.

    PubMed

    Silvestroni, E; Bianco, I; Graziani, B; Carboni, C; Valente, M; Lerone, M; D'Arca, S U

    1980-06-01

    From 1975 to 1979 the Rome Microcythaemia Centre carried out four health education campaigns and thalassaemia screenings among students of the intermediate schools throughout Latium, under the auspices and with the financial support of the Health Authorities of the Latium region. This project is aimed at avoiding reproduction by pairs of thalassaemia carriers and the birth of homozygous children. During the four campaigns 138 501 students were examined, that is, 70 to 76% of those enrolled. Of these 3343 were found to be thalassaemic. Thus the overall prevalence of thalassaemia in Latium is 2.41%, with minor fluctuations from one province to another and, above all, a slight, though definite, trend towards higher values in the southern part of Latium bordering on Campania. The screening was welcomed by the population and the thalassaemic families, there were no detectable negative side-effects, and it resulted in an increased awareness of the problem of the thalassaemias.

  7. [8 years experience with heroin-assited treatment in Switzerland--current results and future improvements].

    PubMed

    Gschwend, P; Eschmann, S; Güttinger, F; Hosek, M; Rehm, J; Uchtenhagen, A

    2003-06-01

    In 1994, Switzerland introduced experimental heroin assisted treatment for refractory opioid addicts as last line of treatment. An evaluation research was established examining effectiveness and cost-benefit of heroin-assisted treatment for the first project phase between 1994 and 1996. The present publication intends to provide an overview for the newer results of the evaluation. In summary, the positive outcomes found at first follow-ups continued to persist regarding somatic and mental improvements, social integration including reduction of criminal behaviour, and reduction of use of illicit drugs. In future, treatment of co-morbid mental disorders, integration into the labour market and persistent consumption of cocaine in some patients still need focussed attention. Different efforts to assure quality control and development hopefully will serve towards further optimisation of heroin-assisted treatment.

  8. Ten Years of Results of Modified Frontalis Muscle Transfer for the Correction of Blepharoptosis

    PubMed Central

    Kim, Woo Jeong; Park, Dae Hwan

    2016-01-01

    Background Conventional frontalis transfer may cause a range of complications. In order to overcome complications, we made modifications to the surgical technique, and compared the outcomes of patients who underwent conventional frontalis transfer with those of patients who underwent modified frontalis transfer. Methods We conducted a retrospective study of 48 patients (78 eyes) who underwent conventional frontalis transfer between 1991 and 2003 (group A) and 67 patients (107 eyes) who underwent modified frontalis transfer between 2004 and 2014 (group B). The frontalis transfer procedures were modified conform to the following principles. The tip of the frontalis muscle flap included soft tissue that was as thick as possible and the soft tissue on the tarsal plate was removed to the greatest extent possible. A double fold was created in cases of unilateral ptosis. In order to evaluate the objective effects of modification, preoperative and postoperative values of the marginal distance reflex 1 (MRD1), the corneal exposure area, and the decrease in eyebrow height were compared between the two groups. Results In group A, patients showed an improvement of 1.19 mm in the MRD1, a 6.31% improvement in the corneal exposure area, and a 7.82 mm decrease in eyebrow height. In group B, patients showed an improvement of 2.17 mm in the MRD1, an 8.39% improvement in the corneal exposure area, and an 11.54 mm decrease in eyebrow height. The improvements in group B were significantly greater than those in group A. Conclusions Modified frontalis transfer showed better results than the conventional procedure and provided satisfactory outcomes. PMID:27019810

  9. Overview of Results from the Cassini Magnetospheric Imaging Instrument (MIMI) During the First Year of Operations

    NASA Technical Reports Server (NTRS)

    Krimigis, S. M.; Mitchell, D. G.; Hamilton, D. C.; Krupp, N.; Livi, S.; Roelof, E. C.; Dandouras, J.; Mauk, B. H.; Brandt, J. P.; Paranicas, C.

    2005-01-01

    The MIMI investigation comprises three sensors covering the indicated energy ranges: the Ion and Neutral Camera (INCA) -- 7 keV/nuc 3 Mev) and protons (1.6 < E < 160 Mev) from the back end of the dual field-of-view telescope. The Saturn observation sequences began in January, 2004 and culminated in Saturn Orbit Insertion on July 1, 2004. The MIMI sensors observed substantial activity in interplanetary space for several months prior to SOI, including several interplanetary shocks associated with corotating interaction regions, numerous increases most likely originating from particle streams in the vicinity of the Saturnian bow shock and energetic neutral atoms (ENA) emanating from Saturn s magnetosphere. Results following SOI revealed: a dynamical magnetosphere with a day-night asymmetry and an 11-hour periodicity; several water-product ions (O+, OH+, H2O+), but little N+; inferred quantities of neutral gas sufficient to cause major losses in the trapped ions and electrons in the middle and inner magnetosphere; a Titan exosphere that is a copious source of ENA; INCA imaging through ENA has also revealed a previously unknown radiation belt residing inward of the D-ring that is most likely the result of double charge-exchange between the main radiation belt and the upper layers of Saturn s exosphere. Finally, there is ample evidence for the presence of substorm-like injections of plasma that subsequently corotates for a number of days before dissipating on the night-side magnetotail. The observations will be presented and discussed in the context of current theoretical models.

  10. Anterior Lumbar Interbody Fusion: Two-Year Results with a Modular Interbody Device

    PubMed Central

    Yeoman, Chevas; Chung, Woosik M.; Chappuis, James L; Freedman, Brett

    2014-01-01

    Study Design Retrospective case series. Purpose To present radiographic outcomes following anterior lumbar interbody fusion (ALIF) utilizing a modular interbody device. Overview of Literature Though multiple anterior lumbar interbody techniques have proven successful in promoting bony fusion, postoperative subsidence remains a frequently reported phenomenon. Methods Forty-three consecutive patients underwent ALIF with (n=30) or without (n=11) supplemental instrumentation. Two patients underwent ALIF to treat failed posterior instrumented fusion. The primary outcome measure was presence of fusion as assessed by computed tomography. Secondary outcome measures were lordosis, intervertebral lordotic angle (ILA), disc height, subsidence, Bridwell fusion grade, technical complications and pain score. Interobserver reliability of radiographic outcome measures was calculated. Results Forty-three patients underwent ALIF of 73 motion segments. ILA and disc height increased over baseline, and this persisted through final follow-up (p<0.01). Solid anterior interbody fusion was present in 71 of 73 motion segments (97%). The amount of new bone formation in the interbody space increased over serial imaging. Subsidence >4 mm occurred in 12% of patients. There were eight surgical complications (19%): one major (reoperation for nonunion/progressive subsidence) and seven minor (five subsidence, two malposition). Conclusions The use of a modular interbody device for ALIF resulted in a high rate of radiographic fusion and a low rate of subsidence. The large endplate and modular design of the device may contribute to a low rate of subsidence as well as maintenance of ILA and lordosis. Previously reported quantitative radiographic outcome measures were found to be more reliable than qualitative or categorical measures. PMID:25346811

  11. Genetic progress resulting from forty-three years of breeding of the carioca common bean in Brazil.

    PubMed

    Barili, L D; Vale, N M; Moura, L M; Paula, R G; Silva, F F; Carneiro, J E S

    2016-08-05

    We aimed to evaluate 40 common bean cultivars recommended by various Brazilian research institutions between 1970 and 2013 and estimate the genetic progress obtained for grain yield and other agronomic traits. Additionally, we proposed a bi-segmented nonlinear regression model to infer the year in which breeding began to show significant gains in Brazil. The experiment was carried out in Viçosa/MG and Coimbra/MG, in the dry and winter seasons of 2013. For this, a randomized complete block design with three replications was employed. The following traits were evaluated: number of pods per plant (NPP); number of seeds per pod (NSP); 1000-seed weight (W1000); grain yield (Yield); plant architecture (Arch); and grain aspect (GA). Genotypic means were estimated over years using linear mixed models, and genetic gains were estimated using bi-segmented nonlinear regression models. In summary, the methodology proposed in the present study indicated that bean breeding programs in Brazil began to influence Yield beginning in 1990, resulting in a gain of 6.74% per year (68.15 kg/ha per year). The years from which estimated genetic progress for NPP (5.62% per year), NSP (4.59% per year), W1000 (2.08% per year), and GA (1.36% per year) began to increase were 1994, 1990, 1989, and 1986, respectively.

  12. Donor Age and Corneal Endothelial Cell Loss 5 Years after Successful Corneal Transplantation: Specular Microscopy Ancillary Study Results

    PubMed Central

    2010-01-01

    Objective To determine whether endothelial cell loss 5 years after successful corneal transplantation is related to the age of the donor. Design Multicenter, prospective, double-masked clinical trial. Participants Three hundred forty-seven subjects participating in the Cornea Donor Study who had not experienced graft failure 5 years after corneal transplantation for a moderate-risk condition (principally Fuchs’ dystrophy or pseudophakic corneal edema). Testing Specular microscopic images of donor corneas obtained before surgery and postoperatively at 6 months, 12 months, and then annually through 5 years were submitted to a central reading center to measure endothelial cell density (ECD). Main Outcome Measure Endothelial cell density at 5 years. Results At 5 years, there was a substantial decrease in ECD from baseline for all donor ages. Subjects who received a cornea from a donor 12 to 65 years old experienced a median cell loss of 69% in the study eye, resulting in a 5-year median ECD of 824 cells/mm2 (interquartile range, 613–1342), whereas subjects who received a cornea from a donor 66 to 75 years old experienced a cell loss of 75%, resulting in a median 5-year ECD of 654 cells/mm2 (interquartile range, 538–986) (P [adjusted for baseline ECD] = 0.04). Statistically, there was a weak negative association between ECD and donor age analyzed as a continuous variable (r [adjusted for baseline ECD] = −0.19; 95% confidence interval, −0.29 to −0.08). Conclusions Endothelial cell loss is substantial in the 5 years after corneal transplantation. There is a slight association between cell loss and donor age. This finding emphasizes the importance of longer-term follow-up of this cohort to determine if this relationship affects graft survival. PMID:18387408

  13. Combined photodynamic therapy and ranibizumab for polypoidal choroidal vasculopathy: a 2-year result and systematic review

    PubMed Central

    Zhao, Meng; Zhou, Hai-Ying; Xu, Jun; Zhang, Feng; Wei, Wen-Bin; Liu, Ning-Pu

    2017-01-01

    AIM To report a cohort of patients with polypoidal choroidal vasculopathy (PCV) treated with photodynamic therapy (PDT) followed by intravitreal ranibizumab injection 24-48h later, and to compare the results between eyes with PCV treated by PDT followed by intravitreal anti-vascular endothelial growth factor (VEGF) injection and intravitreal anti-VEGF injection followed by PDT by Meta-analysis. METHODS Retrospective study and systematic literature review. Medical records of patients with PCV who were initially treated using PDT followed by intravitreal ranibizumab injection 24-48h after PDT and had completed at least 2y follow-up were reviewed and analyzed. Clinical data, including age, sex, best-corrected visual acuity (BCVA), fundus photograph, fluorescein angiography, indocyanine green angiography and optical coherence tomography were investigated. A systematic literature review was also conducted, and a visual outcome of studies over 1y was compared using Meta-analysis. RESULTS A total of 52 patients were included in the study. Mean BCVA at baseline and follow-up at 1 or 2y were 0.71±0.61, 0.51±0.36 and 0.68±0.51 logMAR, respectively. The cumulative hazard rate for recurrence at 1 and 2y follow-up was 15.4% and 30.3% respectively. The percentage of eyes with polyps regression at 3, 12 and 24mo follow-up was 88.5%, 84.6% and 67.3% respectively. A Meta-analysis based on 22 independent studies showed the overall vision improvements at 1, 2 and 3y follow-up were 0.13±0.04 (P<0.001), 0.12±0.03 (P<0.001), 0.16±0.06 (P<0.001), respectively. The proportion of polyps regression at 1y follow-up was 64.6% (95%CI: 51.5%, 77.7%, P<0.001) in 434 eyes treated by intravitreal anti-VEGF agents before PDT and 76.0% (95%CI: 64.8%, 87.3%, P=0.001) in 199 eyes treated by intravitreal anti-VEGF agents after PDT. CONCLUSION Intravitreal ranibizumab injection 24-48h following PDT effectively stabilizes visual acuity in the eye with PCV. PDT followed by intravitreal anti

  14. Tank Inspection NDE Results for Fiscal Year 2014, Waste Tanks 26, 27, 28 and 33

    SciTech Connect

    Elder, J.; Vandekamp, R.

    2014-09-29

    Ultrasonic nondestructive examinations (NDE) were performed on waste storage tanks 26, 27, 28 and 33 at the Savannah River Site as a part of the “In-Service Inspection (ISI) Program for High Level Waste Tanks.” No reportable conditions were identified during these inspections. The results indicate that the implemented corrosion control program continues to effectively mitigate corrosion in the SRS waste tanks. Ultrasonic inspection (UT) is used to detect general wall thinning, pitting and interface attack, as well as vertically oriented cracks through inspection of an 8.5 inch wide strip extending over the accessible height of the primary tank wall and accessible knuckle regions. Welds were also inspected in tanks 27, 28 and 33 with no reportable indications. In a Type III/IIIA primary tank, a complete vertical strip includes scans of five plates (including knuckles) so five “plate/strips” would be completed at each vertical strip location. In FY 2014, a combined total of 79 plate/strips were examined for thickness mapping and crack detection, equating to over 45,000 square inches of area inspected on the primary tank wall. Of the 79 plate/strips examined in FY 2014 all but three have average thicknesses that remain at or above the construction minimum thickness which is nominal thickness minus 0.010 inches. There were no service induced reportable thicknesses or cracking encountered. A total of 2 pits were documented in 2014 with the deepest being 0.032 inches deep. One pit was detected in Tank 27 and one in Tank 33. No pitting was identified in Tanks 26 or 28. The maximum depth of any pit encountered in FY 2014 is 5% of nominal thickness, which is less than the minimum reportable criteria of 25% through-wall for pitting. In Tank 26 two vertical strips were inspected, as required by the ISI Program, due to tank conditions being outside normal chemistry controls for more than 3 months. Tank 28 had an area of localized thinning on the exterior wall of the

  15. High-school smoking prevention: results of a three-year longitudinal study.

    PubMed

    Johnson, C A; Hansen, W B; Collins, L M; Graham, J W

    1986-10-01

    This study compared two strategies for preventing cigarette smoking among high-school students. One strategy emphasized social-pressure resistance skills, while the other focused on education about health concerns which are relevant to high-school students. Additionally, the use of same-age peer leaders and the use of familiar models in media presentations were investigated. The results suggest that social-influences resistance training was efficacious in reducing transitions to higher use by those who had previously experimented with cigarettes. Health education was most effective in preventing initial experimentation among those who had not smoked prior to the beginning of the study. Neither program was effective in limiting transitions among those who had gone beyond the experimental stage of smoking, and neither had any effect on encouraging cessation. There were no differences which could be attributed to peer leaders or to familiar media models. During later adolescence, a combined health education and social skills training approach is advocated. It is suggested that while there are some gains by implementing programs during late adolescence, prevention programs targeted at younger students may be more effective generally.

  16. Degree Angular Scale Interferometer 3 Year Cosmic Microwave Background Polarization Results

    NASA Astrophysics Data System (ADS)

    Leitch, E. M.; Kovac, J. M.; Halverson, N. W.; Carlstrom, J. E.; Pryke, C.; Smith, M. W. E.

    2005-05-01

    We present the analysis of the complete 3 yr data set obtained with the Degree Angular Scale Interferometer (DASI) polarization experiment, operating from the Amundsen-Scott South Pole research station. New data obtained at the end of the 2002 austral winter and throughout the 2003 season were added to the data from which the first detection of polarization of the cosmic microwave background (CMB) radiation was reported. The analysis of the combined data supports, with increased statistical power, all of the conclusions drawn from the initial data set. In particular, the detection of E-mode polarization is increased to the 6.3 σ confidence level, TE cross-polarization is detected at 2.9 σ, and B-mode polarization is consistent with zero, with an upper limit well below the level of the detected E-mode polarization. The results are in excellent agreement with the predictions of the cosmological model that has emerged from CMB temperature measurements. The analysis also demonstrates that contamination of the data by known sources of foreground emission is insignificant.

  17. Sulphur dioxide in meat products: 3-year control results of an accredited Italian laboratory.

    PubMed

    Iammarino, Marco; Ientile, Anna Rita; Di Taranto, Aurelia

    2017-06-01

    Sulphiting agents are well-known food preservatives. The European legislation does not allow their addition in fresh meat preparations. Therefore this type of food products has often been verified. To high sulphite levels in food is a health safety risk, due to toxic effects that these compounds may exercise on humans. In this study the control activity as performed by an Italian accredited laboratory from 2013 to 2015, relating to determination of sulphites in meat products, is described. Six hundred and sixty-nine meat product samples were analysed. Both applied techniques, a screening method (malachite green test) and a confirmatory method (ion chromatography), were accredited. Forty-three samples resulted positive at screening test and nineteen of these samples showed high-sulphite concentrations, in the range 67.6-1437 mg kg(-1). The non-negligible percentage of positives (6.4%) and the high concentrations verified confirmed that the control of sulphuring treatment of fresh meat preparations is an important task for organisations in charge of food inspections and control.

  18. Results of Dose Control and Measurement Plans Appliedfor SPEAR3 Commissioning Year (FY04)

    SciTech Connect

    Khater, Hesham; Liu, James; Prinz, Alyssa; Allan, Jim; Rokni, Sayed; /SLAC

    2007-02-12

    Dose control and measurement plans for the SPEAR3 Booster and storage ring have taken place during the SPEAR3 commissioning. The initial commissioning period (SPEAR3 start-up) covered the time period from the beginning of November 2003 to the early part of March 2004. The period from the beginning of March to the beginning of August 2004 has been mostly dedicated to the scientific program. The initial commissioning period was characterized with frequent injection and significantly higher losses. In comparison, the scientific program period was characterized with more stable beam operation with limited number of injections per day and lower beam losses. Three types of dose measurements, passive, active and special measurements, were implemented around the SPEAR3 Booster and storage ring. Based on the expected radiation hazards, several dose control measures were adopted at several stages of the commissioning. In the early stages of commissioning, areas within 4.5 m from the walls of the Booster and storage ring were designated as Radiation Areas (RA). Areas outside RA were classified as Radiologically Controlled Area (RCA). Access to these areas required less training than the radiation areas. A monthly review of the accelerator operation conditions and radiation measurement results were used to determine the changes needed for the RA classification status and associated dose control measures.

  19. PM10: results of a one-year monitoring survey in the Netherlands

    SciTech Connect

    van der Meulen, A.; van Elzakker, B.G.; van den Hooff, G.N.

    1987-07-01

    A comprehensive field assessment has been made of the measurement performance of PM10 inlets. Both precision and comparability are approximately 4 percent, complying well with the requirements of the proposed Federal Reference Method (FRM). Fluctuations in sampling efficiency play a dominant role. Hence, both comparability and precision can be interpreted in terms of changes in the 50 percent cutoff diameter D50. In this way a D50 performance of about 0.7 ..mu..m is deduced, clearly within the proposed FRM requirement of D50 = 10 +/- 1 ..mu..m. There exists no fixed linear relationship between PM10 and TSP (total suspended particulate matter): different average situations yield different regression coefficients (Western Europe: 0.7 and USA: 0.5). Furthermore, there are different conversion factors, representative of average (0.5-0.7) or episodic situations of high concentration levels (0.8-0.9). Hence, TSP air quality standards should not be replaced by PM10 ones simply by using the regression results from various national studies because this could yield unequal stringent PM10 standards.

  20. Analyzing Exercise Behaviors during the College Years: Results from Latent Growth Curve Analysis

    PubMed Central

    Wittman, Werner

    2016-01-01

    The objective of this study is to analyze changes in the predictors of physical activity behavior among college students. The Theory of Planned Behavior served as its theoretical framework. Methods: Among an initial sample of 417 college students, 195 participants completed a validated questionnaire measuring attitudes, subjective norms, perceived control, intentions and self-reported physical activity, at the beginning and end of each of 3 college semesters. Latent growth curve modeling analyses were conducted to examine the relationships between the trajectories of changes in PA, intentions, attitudes, subjective norms, and perceived control. Results: Good fit indices supported the validity of the proposed longitudinal model (CFI > .97, RMSEA < .05). Changes in perceived control (γ = 0.57) were significantly linked with changes in intentions (p < .05). Perceived control (γ = 0.28) and intention growth (γ = 0.36) predicted behavior changes (p < .05). No gender differences were observed on attitudes, subjective norms and perceived control (p > .10). However, girls tend to have higher growth parameters on intentions and physical activity (p < .05). In summary, intentions and physical activity has significantly increased over 3 college semesters (growth parameters significant at p < .05). Conclusions: This study demonstrated that attitudes and perceived control are key determinants regarding the intentions of being active. On a longer term perspective, future physical activity interventions should focus on the enhancement of students’ perceived control. Such educational context should help in promoting the adoption of an active lifestyle during college. PMID:27124179

  1. Ten years of laser treatment of congenital vascular disorders: techniques and results

    NASA Astrophysics Data System (ADS)

    Philipp, Carsten M.; Berlien, Hans-Peter; Poetke, Margitta; Waldschmidt, Juergen

    1994-12-01

    During the period of January 1984 - July 1993, we have treated 611 children with more than 2000 lesions of congenital vascular disorders (CVD) such as hemangiomas and vascular malformations. This number does not include the patients with port wine stains, which also have been treated by means of laser. Most of the CVD patients (n equals 467) presented hemangiomas of the face, the anogenital region, and the extremities, some were located in the trachea or mouth or in the urogenital tract. All of these hemangiomas were growing prior to intervention or showed complications such as bleeding, ulceration, superinfection, or obstruction. Nearly a quarter (n equals 144) of the patients presented vascular malformations, either of singular vessel type involvement or of mixed vascular genesis (venous, arterio- venous, veno-lymphatic or lymphatic) with various complications like tracheal obstruction or recurrent thrombophlebitis. According to our step program, which is based on a clinical classification, the hemangiomas were treated as early as possible, while the vascular malformations were only treated with laser when no other therapeutic technique (embolization, resection) was suitable. All patients were referred for laser treatment from other centers. The lasers used were Nd:YAG and Argon lasers with transcutaneous application with or without continuous ice-cube surface cooling or interstitial laser application. The treatments were performed either on in- or outpatient basis according to age, localization and with good to excellent results in most cases and a complication rate of less than 2%.

  2. Femoral revision with taper stems: results at ten years follow-up.

    PubMed

    Cherubino, Paolo; Fagetti, Alessandro; D'Angelo, Fabio; Surace, Michele Francesco

    2010-10-01

    In the case of extensively damaged meta-diaphyseal femoral bone with cortices thinning and widened femoral canal, tapered stems allow a good primary fixation and early weight-bearing. A retrospective review was conducted to evaluate long-term results of modular revision taper stems implanted from March 1999 to December 2002. Sixty-five consecutive hip revision surgeries were performed, mostly for aseptic loosening (75% of the cases). Femoral bone stock defects were classified according to AAOS's criteria and consisted mainly in type II (cavitary defects, 44.6%) and type III (combined defects, 33.9%). A trochanteric osteotomy was performed in 25 cases (38%) to remove primary implants that were cemented in 35 cases (54%). The mean postoperative follow-up was 109 months (range, 76 to 131 months). Clinical assessment at follow-up showed a significantly improved mean Harris Hip Score from 42 points preoperatively to 81 points postoperatively, while the x-ray examination did show a satisfactory distal integration of the stem in all cases and satisfactory reconstitution of the femoral bone stock in 47% of cases. The average subsidence of the stem at follow-up was less than one millimeter. According to data analysis, a leg-length discrepancy exceeding 15 millimeters caused significantly worse functional outcome and pain.

  3. The First Half Billion Years (z > 9): Results from the Frontier Fields

    NASA Astrophysics Data System (ADS)

    Coe, Dan A.; Bradley, Larry D.

    We present z > 9 candidates identified in Hubble Frontier Fields imaging of the first four clusters and blank parallel fields (two-thirds of the complete program). Based on the deeper Hubble imaging, we revise the redshift estimate of the CLASH z ~ 9.6 candidate MACS1149-JD to z = 9.2+0.2 -0.5 (95% C.L.). We identify a new possible fainter z ~ 9 companion 3'' away (~1 kpc in the source plane). And we discover a new z ~ 9.2 candidate in the MACS1149 parallel field. Combined with previously published candidates at z ~ 9.8 and 9.1 (in A2744 and its parallel field, respectively), these five z > 9 candidates fall below our published expectation of 8 - 47 at this stage in the program. We attribute some of this shortfall to incompleteness, which we have yet to quantify. At z ~ 8 (7.5 - 8.5), we detect 26 candidates down to F160W H < 28.7 AB, roughly one-third the ~82 we expect. If our z > 9 incompleteness is similar (~68%), our results would support the sharp drop in z > 9 number counts claimed by some (but not all) previous works and supported by several (but not all) theoretical models. Properly quantifying our incompleteness will require adding simulated high-redshift galaxies into the images and testing our recovery rate. Additionally, incorporating the deep Spitzer imaging into our analysis could potentially significantly improve our identification of z > 9 candidates by rejecting low-redshift (z ~ 2) interlopers. Data from the full Frontier Fields program will provide strong evidence for or against accelerated evolution and a sharp drop in the cosmic star formation rate density at z > 9.

  4. A 500-year overview and analysis of flood changes in Europe: preliminary results

    NASA Astrophysics Data System (ADS)

    Kiss, Andrea

    2014-05-01

    Long-term flood series can be gained by combining evidence and systematic hydrological observations. Following various already existing local and regional studies, an important aim of the present work is to create a broad European database of long flood chronologies and to use them for detecting changes in flood regimes with respect to common break points. Another aim of the investigations is to reveal the main causes (e.g. atmospheric, human) of these changes and study spatial and temporal variability of floods on a European scale. In the presentation we provide an overview on the current stage of these Europe-wide investigations, including the available source types (i.e. documentary and instrumental), geographical coverage, temporal and spatial distribution of long-term flood series applied in the study. The first research results concerns basic information on magnitude, frequency and seasonality of floods (with special consideration of detectable changes). Full list of authors in alphabetic order: Mariano Barriendos (1), Günter Blöschl (2), Rudolf Brázdil (3), Gerardo Benito (4), Chiara Bertolin (5), Dario Camuffo (5), Gaston Demarée (6), Líbor Elleder (7), Silvi Enzi (8), Rüdiger Glaser (9), Julia Hall (2), Andrea Kiss (2), Oldrich Kotyza (10), Carmen Maria del Llasat (1), Neil MacDonald (11), Rui Perdigao (2), Dag Retsö (12), Lars Roald (13), Josep Luis Ruiz Bellet (1), Johannes Schönbeim (9), Petra Schmocker-Fackel (14), Lothar Schulte (1), Hubert Valasek (15), Oliver Wetter (16) (1) Faculty of Geography and History, University of Barcelona, Spain (2) Institute of Hydrological Engineering and Water Resources Management, TU Wien (3) Institute of Geography, Masaryk University Brno, Czech Republic (4) Laboratory of Hydrology and Geomorphology, Center of Env. Sciences, Madrid, Spain (5) Institute of Atmospheric Sciences and Climate, National Research Council, Rome, Italy (6) Royal Meteorological Institute, Brussels, Belgium (7) Research Group of

  5. The ILAN sprite campaigns in Israel: results from 7 years of observations

    NASA Astrophysics Data System (ADS)

    Yair, Yoav; Rubanenko, Lior; Katzenelson, Dor; Rosenthal, Neta; Mezuman, Keren; Price, Colin

    2014-05-01

    The ILAN (Imaging of Lightning And Nocturnal flashes, http://ilanteam.com/) campaigns have been conducted since 2004 from Israel, observing winter thunderstorms in the eastern Mediterranean. We searched for transient luminous events using the standard commercial CCD cameras (Watec N100, 902H2 Ultimate) and the UFO-capture software for event detection, commonly used by other TLE- research groups in Europe and Japan. Winter thunderstorms mostly occur in conjunction with the passage of cold fronts in Cyprus lows, and thus TLEs are best observed when the storms are 200-300 km west of the Israeli coastline, above the Mediterranean Sea. We present statistical analysis of 505 sprites observed in 7 winter campaigns from 2006/7-2012/13. Results show a clear peak in the frequency of sprite detections, with maximum values (above 40% of events) between 00:30-02:50 LST (Local Standard Time, UT+2). This distribution is very different from that of lightning in the region, which peaks ~ 05:00 LST over the sea (Altaratz et al., 2001), hinting at the different temporal behavior of +CG flashes, known to be the major producers of sprites. The morphological distribution of 339 sprites is dominated by column sprites (49.3%) with angels (33.0%) and carrots (25.7%) being less frequent. This is similar to reports of winter sprites over the Sea of Japan (Matsudo et al., 2007). Other shapes (trees, wishbones, etc.; Bór, 2013) appear quite rarely. Single element events constitute 16.8% of observations, with 83.2% containing 2 elements or more. Clusters of homogenous types are slightly more frequent than mixed ones (55%). In some rare cases we observed 12-23 elements in a single sprite. The number of elements and the temporal distribution of different sprite types will be presented and compared with the properties of the parent thunderstorms. Altaratz, O., Levin Z. and Y. Yair, 2001: Winter thunderstorms in Israel - a study with lightning location systems and weather radar. Month. Weath. Rev

  6. Gemini Planet Imager Exoplanet Survey: Key Results Two Years Into The Survey

    NASA Astrophysics Data System (ADS)

    Marchis, Franck; Rameau, Julien; Nielsen, Eric L.; De Rosa, Robert J.; Esposito, Thomas; Draper, Zachary H.; Macintosh, Bruce; Graham, James R.; GPIES

    2016-10-01

    The Gemini Planet Imager Exoplanet Survey (GPIES) is targeting 600 young, nearby stars using the GPI instrument. We report here on recent results obtained with this instrument from our team.Rameau et al. (ApJL, 822 2, L2, 2016) presented astrometric monitoring of the young exoplanet HD 95086 b obtained with GPI between 2013 and 2016. Efficient Monte Carlo techniques place preliminary constraints on the orbital parameters of HD 95086 b. Under the assumption of a coplanar planet-disk system, the periastron of HD 95086 b is beyond 51 AU. Therefore, HD 95086 b cannot carve the entire gap inferred from the measured infrared excess in the SED of HD 95086. Additional photometric and spectroscopic measurements reported by de Rosa et al. (2016, apJ, in press) showed that the spectral energy distribution of HD 95086 b is best fit by low temperature (T~800-1300 K), low surface gravity spectra from models which simulate high photospheric dust content. Its temperature is typical to L/T transition objects, but the spectral type is poorly constrained. HD 95086 b is an important exoplanet to test our models of atmospheric properties of young extrasolar planets.Direct detections of debris disk are keys to infer the collisional past and understand the formation of planetary systems. Two debris disks were recently studied with GPI:- Draper et al. (submitted to ApJ, 2016) show the resolved circumstellar debris disk around HD 111520 at a projected range of ~30-100 AU using both total and polarized H-band intensity. Structures in the disks such as a large brightness asymmetry and symmetric polarization fraction are seen. Additional data would confirm if a large disruption event from a stellar fly-by or planetary perturbations altered the disk density- Esposito et al. (submitted to ApJ, 2016) combined Keck NIRC2 data taken at 1.2-2.3 microns and GPI 1.6 micron total intensity and polarized light detections that probes down to projected separations less than 10 AU to show that the HD

  7. Field Lysimeter Investigations - test results: Low-Level Waste Data Base Development Program: Test results for fiscal years 1994-1995

    SciTech Connect

    McConnell, J.W. Jr.; Rodgers, R.D.; Hilton, L.D.; Neilson, R.M. Jr.

    1996-06-01

    The Field Lysimeter Investigations: Low-Level Waste Data Base Development Program, funded by the U.S. Nuclear Regulatory Commission (NRC), is (1) studying the degradation effects in EPICOR-II organic ion-exchange resins caused by radiation, (2) examining the adequacy of test procedures recommended in the Branch Technical Position on Waste Form to meet the requirements of 10 CFR 61 using solidified EPICOR-II resins, (3) obtaining performance information on solidified EPICOR-II ion-exchange resins in a disposal environment, and (4) determining the condition of EPICOR-II liners. Results of the final 2 (10 total) years of data acquisition from operation of the field testing are presented and discussed. During the continuing field testing, both portland type I-II cement and Dow vinyl ester-styrene waste forms are being tested in lysimeter arrays located at Argonne National Laboratory-East in Illinois and at Oak Ridge National Laboratory. The experimental equipment is described and results of waste form characterization using tests recommended by the NRC`s {open_quotes}Technical Position on Waste Form{close_quotes} are presented. The study is designed to provide continuous data on nuclide release and movement, as well as environmental conditions, over a 20-year period. At the end of the tenth year, the experiment was closed down. Examination of soil and waste forms is planned to be conducted next and will be reported later.

  8. RECONSTRUCTION OF THE ANTERIOR CRUCIATE LIGAMENT WITH THE CENTRAL THIRD OF THE QUADRICEPS MUSCLE TENDON: ANALYSIS OF 10-YEAR RESULTS

    PubMed Central

    Guimarães, Marcus Valladares; Junior, Lúcio Honório de Carvalho; Terra, Dalton Lopes

    2015-01-01

    Objective: Assess clinical results using two different protocols, 10 years after ACL reconstruction surgery with the central third of quadriceps muscle tendon (QT). Method: Between November /1997 and April/1998, 25 patients were submitted to 25 ACL reconstructions with QT by transtibial technique. The bone portion of the graft was fixated on femoral tunnel with interference screw and the tendinous portion of tibial tunnel with screw with washer. Two patients injured the new when playing soccer. Six patients were not available for follow-up (24%). Seventeen patients were evaluated, 15 men and two women, with mean age at surgery time of 28.53 ± 6.64 years. All patients were examined at six months, one year, and ten years after surgery. Clinical evaluation was made by the Lysholm scale, and the knee evaluation, with the Hospital for Special Surgery scale. Results: The patients had their injuries operated after 9.87 ± 14.42 months of the accident. According to Lysholm scale, the results at the end of the first year were 98.71 ± 2.47 and, after 10 years, 97.35 ± 3.12. Using the Hospital for Special Surgery scale, the mean score was 95.07 ± 5.23 in one year, and 94.87 ± 4.16 in 10 years. All patients returned to their professional activities with the same previous status. Fifteen (88.24%) patients were able to return to their sports activities, one by modifying the practice, while another one switched to another sport. No patient complained of pain on the donor area in the medium and long term. The sports return rate was excellent, and no changes were found on the femoropatellar joint. PMID:27022511

  9. Evaluation of the results from arthroscopic surgical treatment of rotator cuff injuries in patients aged 65 years and over☆

    PubMed Central

    Miyazaki, Alberto Naoki; da Silva, Luciana Andrade; Santos, Pedro Doenux; Checchia, Sergio Luiz; Cohen, Carina; Giora, Taís Stedile Busin

    2015-01-01

    Objectives To evaluate the results from arthroscopic surgical treatment of rotator cuff injuries in patients aged 65 years and over. Methods Between 1998 and 2009, 168 patients underwent operations. Five cases were excluded. The remaining 163 patients were stratified according to their age group: 65–69 years (49.1%), 70–74 (26.4%) and 75 years and over (24.5%). Their mean age was 71 years (range: 65–83). There were 63 male patients (38.7%). The mean length of time with pain, from the onset of symptoms to the surgery, was 23 months (range: 2 days to 240 months). Sixty-two patients (38%) reported histories of trauma and 26 (16%) reported that their pain worsened through exertion. Results From the UCLA criteria, 80.4% of the results were excellent, 16% good, 1.8% fair and 1.8% poor. Complications occurred in 11%. The final clinical result did not show any correlation with age progression, injury size or tendons affected. However, there was a significant association (p < 0.001) between the presence of trauma and larger injuries. The length of time between the onset of symptoms and the surgical procedure had a significant relationship (p < 0.027) with the postoperative results: the longer this time was, the worse the results were. Conclusion Arthroscopic treatment of rotator cuff injuries in patients aged 65 years and over presented excellent and good results in 96.4% of the cases, according to the UCLA assessment, with a low complication rate. Advanced age did not show any influence on the postoperative clinical evolution, but the earlier the surgical treatment was instituted, the better the results were. PMID:26229935

  10. Modular stem fixed-bearing total ankle replacement: prospective results of 23 consecutive cases with 3-year follow-up.

    PubMed

    Brigido, Stephen A; Galli, Melissa M; Bleazey, Scott T; Protzman, Nicole M

    2014-01-01

    In the present report, the 3-year outcomes of 23 consecutive patients treated with a modular stem fixed-bearing total ankle replacement are described. Pain, functional impairment, and disability were assessed annually using a visual analog scale. Complications and additional procedures also were recorded. Compared with preoperative pain (8.4 ± 1.4), functional impairment (8.7 ± 2.3), and disability (3.0 ± 2.5), there were statistically significant postoperative improvements at 1 year (pain, 2.6 ± 1.6; functional impairment, 3.1 ± 2.1; disability, 0.9 ± 1.2), 2 years (pain, 1.5 ± 1.3; functional impairment, 1.9 ± 1.4; disability, 0.6 ± 1.4), and 3 years (pain, 1.3 ± 1.3; functional impairment, 1.9 ± 1.9; disability, 0.4 ± 0.9; p ≤ .001). Pain, function, and disability significantly improved postoperatively from 1 to 2 years (p ≤ .008) and from 1 to 3 years (p ≤ .008). The reductions in pain, functional impairment, and disability were maintained from 2 to 3 years (p ≥ .08). Nine complications (39.1%) were encountered: 1 deep infection, 2 pulmonary embolisms, 3 wounds, 1 ectopic bone formation, 1 stiff joint, and 1 talar subsidence. In the 3-year follow-up period, 3 patients (13.0%) required additional procedures after the immediate postoperative phase. Our results have demonstrated that modular stem fixed-bearing prostheses can be implanted in a predictable and consistent fashion with resultant improvements in pain, function, and disability. Future studies evaluating the clinical outcomes after modular stem fixed-bearing total ankle replacement are warranted.

  11. Closed reduction for congenital dysplasia of the hip. Functional and radiographic results after an average of thirty years.

    PubMed

    Malvitz, T A; Weinstein, S L

    1994-12-01

    The functional and radiographic results of closed reduction in 152 congenitally dislocated hips of 119 patients who had been managed between 1938 and 1969 were reviewed retrospectively. The average age of the patients at the time of the reduction was twenty-one months (range, one to ninety-six months). At the time of the latest follow-up evaluation, the average age was thirty-one years (range, sixteen to fifty-six years). The average duration of follow-up was thirty years (range, fifteen to fifty-three years). At the latest follow-up evaluation, the Iowa hip rating averaged 91 points (range, 38 to 100 points) and the Harris hip score averaged 90 points (range, 33 to 100 points). Thirty-five hips were rated Severin Class I; thirty-five, Class II; twenty-eight, Class III; fifty-three, Class IV; and one, Class VI. Disturbance of growth in the proximal end of the femur occurred in ninety-one hips (60 per cent). Eight contralateral hips that had appeared normal also demonstrated disturbance of proximal femoral growth. In many hips, partial physeal arrest could not be determined for ten to twelve years after the reduction. Seventeen hips (twelve patients) had a total replacement when the patients were an average age of thirty-six years (range, nineteen to fifty-three years). Sixty-five hips (43 per cent) had radiographic evidence of degenerative joint disease. Patients who did not have a growth disturbance of the proximal end of the femur or evidence of subluxation tended to function extremely well for many years despite a radiographic result that was less than anatomical. Function tended to deteriorate with time, even in the absence of disturbance of growth in the proximal end of the femur. Despite generally good function at the latest follow-up evaluation, the prognosis for these patients remained guarded.

  12. Mid-to long-term results of revision total hip replacement in patients aged 50 years or younger.

    PubMed

    Lee, P T H; Lakstein, D L; Lozano, B; Safir, O; Backstein, J; Gross, A E

    2014-08-01

    Revision total hip replacement (THR) for young patients is challenging because of technical complexity and the potential need for subsequent further revisions. We have assessed the survivorship, functional outcome and complications of this procedure in patients aged < 50 years through a large longitudinal series with consistent treatment algorithms. Of 132 consecutive patients (181 hips) who underwent revision THR, 102 patients (151 hips) with a mean age of 43 years (22 to 50) were reviewed at a mean follow-up of 11 years (2 to 26) post-operatively. We attempted to restore bone stock with allograft where indicated. Using further revision for any reason as an end point, the survival of the acetabular component was 71% (sd 4) and 54% (sd 7) at ten- and 20 years. The survival of the femoral component was 80% (sd 4) and 62% (sd 6) at ten- and 20 years. Complications included 11 dislocations (6.1%), ten periprosthetic fractures (5.5%), two deep infections (1.1%), four sciatic nerve palsies (2.2%; three resolved without intervention, one improved after exploration and freeing from adhesions) and one vascular injury (0.6%). The mean modified Harris Hip Score was 41 (10 to 82) pre-operatively, 77 (39 to 93) one year post-operatively and 77 (38 to 93) at the latest review. This overall perspective on the mid- to long-term results is valuable when advising young patients on the prospects of revision surgery at the time of primary replacement.

  13. Comprehensive Employment and Training Act. Review and Oversight. Part I: Background and First Year Results. Part II: Public Policy Issues.

    ERIC Educational Resources Information Center

    Employment and Training Administration (DOL), Washington, DC.

    This report reviews the establishment and early performance of the comprehensive manpower system established by the Comprehensive Employment and Training Act (CETA). The report is divided into two major sections. Part 1 examines the background and first year results of the CETA program. The legislative and programmatic antecedents to CETA are…

  14. The Contribution of the Responsive Classroom Approach on Children's Academic Achievement: Results from a Three Year Longitudinal Study

    ERIC Educational Resources Information Center

    Rimm-Kaufman, Sara E.; Fan, Xitao; Chiu, Yu-Jen; You, Wenyi

    2007-01-01

    This paper reports the results of a quasi-experimental study on the contribution of the Responsive Classroom ("RC") Approach to elementary school children's reading and math performance over one-, two-, and three-year periods. All children enrolled in six schools (3 intervention and 3 control schools in a single district) were the participants in…

  15. Reducing Overt and Relational Aggression among Young Children: The Results from a Two-Year Outcome Evaluation

    ERIC Educational Resources Information Center

    Boyle, Douglas; Hassett-Walker, Connie

    2008-01-01

    This paper presents the results of an independent two-year evaluation of the I Can Problem Solve (ICPS) universal prevention program, implemented in kindergarten and first grade classrooms in a racially and ethnically diverse urban school district. Matched pairs of schools were assigned to Instruction (i.e., treatment) or Control status. Teachers…

  16. Splitting Reexamined: Results from a Three-Year Longitudinal Study of Children in Grades Three to Five.

    ERIC Educational Resources Information Center

    Confrey, Jere; Scarano, Grace Hotchkiss

    This paper is a report on the results of a 3-year teaching experiment conducted in Ithaca, New York, introducing students to the concepts of multiplication, division, and ratio as a trio, and to ratio and proportion in a project-based curriculum with heterogeneous grouping. Fractions were introduced as a subset of ratio and proportion. The paper…

  17. What’s Causing Toxicity in Sediments? Results of Twenty Years of Toxicity Identification and Evaluations (TIEs)

    EPA Science Inventory

    Sediment Toxicity Identification and Evaluation (TIEs) methods have been used for twenty years to identify the causes of toxicity in sediments around the world. We summarized and categorized results of more than 80 peer-reviewed TIE studies into non-ionic organic, cationic, ammo...

  18. The Low Profile Bioprosthesis: Results with 491 Valves Implanted in 453 Patients for up to 5 Years

    PubMed Central

    Navia, J. A.; Gimenez, C.; Tamashiro, A.; Esper, R.; Haller, J.; Liotta, D.

    1982-01-01

    This report summarizes results of the first 453 consecutive patients who had 491 low profile bioprostheses implanted at the Italian Hospital in Buenos Aires over a 5-year period. During this time, with the goal of long-term durability, the valve mounting technique was slightly modified, whereas the materials and design of the annulus underwent more extensive changes. Images PMID:15226950

  19. A Year in Space: Early Results and Lessons Learned from the First Year-Long Expedition Aboard the International Space Station

    NASA Technical Reports Server (NTRS)

    Charles, J. B.; Bogomolov, V. V.

    2016-01-01

    the astronaut and cosmonaut to perform rudimentary tasks requiring sensorimotor coordination immediately after landing to define human capabilities soon after landing on Mars after an extended transit. Both investigations were highly successful in large part to the thorough integration of the implementation processes of the two partners. Kelly's assignment as the one-year crewmember also provided a serendipitous opportunity for the "Twins Study" comparing changes in his body at the genetic level with those occurring on Earth in his identical twin brother Mark Kelly. Data analysis from this expedition will commence in earnest after frozen in-flight samples are delivered to Earth in May aboard a commercial cargo spacecraft. Detailed results are expected in early 2017. Preliminary results and implementation improvements will be reviewed in this presentation.

  20. Long-Term Outcomes of Lumbar Spinal Stenosis: Eight-Year Results of the Spine Patient Outcomes Research Trial (SPORT)

    PubMed Central

    Lurie, Jon D.; Tosteson, Tor D.; Tosteson, Anna; Abdu, William A; Zhao, Wenyan; Morgan, Tamara S.; Weinstein, James N.

    2014-01-01

    Study Design Randomized trial with a concurrent observational cohort study Objective To compare 8-year outcomes of surgery to non-operative care for symptomatic lumbar spinal stenosis (SpS) Summary of Background Data Surgery for SpS has been shown to be more effective compared to non-operative treatment over four years, but longer-term data is less clear. Methods Surgical candidates from 13 centers in 11 U.S. states with at least 12 weeks of symptoms and confirmatory imaging were enrolled in a randomized cohort (RCT) or observational cohort (OBS). Treatment was standard decompressive laminectomy versus standard non-operative care. Primary outcomes were SF-36 bodily pain (BP) and physical function (PF) scales and the modified Oswestry Disability index (ODI) assessed at 6 weeks, 3 months, 6 months and yearly up to 8 years. Results 55% of RCT and 52% of OBS participants provided data at the 8-year follow-up. Intent-to-treat analyses showed no differences between randomized cohorts; however, 70% of those randomized to surgery and 52% of those randomized to non-operative had undergone surgery by 8 years. As-treated analyses in the RCT showed the early benefit for surgery out to 4 years converged over time with no significant treatment effect of surgery seen in years 6–8 for any of the primary outcomes. In contrast, the OBS group showed a stable advantage for surgery in all outcomes between years 5–8. Patients who were lost to follow-up were older, less well-educated, sicker, and had worse outcomes over the first 2 years in both surgery and non-operative arms. Conclusions Patients with symptomatic spinal stenosis show diminishing benefits of surgery in as-treated analyses of the RCT between 4–8 years while outcomes in the OBS group remained stable. Loss to follow-up of patients with worse early outcomes in both treatment groups could lead to overestimates of long-term outcomes, but likely not bias treatment effect estimates. PMID:25569524

  1. Intermediate clinical and radiological results of cervical TDR (Mobi-C®) with up to 2 years of follow-up

    PubMed Central

    Beaurain, J.; Bernard, P.; Dufour, T.; Fuentes, J. M.; Hovorka, I.; Huppert, J.; Steib, J. P.; Vital, J. M.; Aubourg, L.

    2009-01-01

    The interest in cervical total disc replacement (TDR) as an alternative to the so-far gold standard in the surgical treatment of degenerative disc disease (DDD), e.g anterior cervical discectomy and fusion (ACDF), is growing very rapidly. Many authors have established the fact that ACDF may result in progressive degeneration in adjacent segments. On the contrary, but still theoretically, preservation of motion with TDR at the surgically treated level may potentially reduce the occurrence of adjacent-level degeneration (ALD). The authors report the intermediate results of an undergoing multicentre prospective study of TDR with Mobi-C® prosthesis. The aim of the study was to assess the safety and efficacy of the device in the treatment of DDD and secondary to evaluate the radiological status of adjacent levels and the occurrence of ossifications, at 2-year follow-up (FU). 76 patients have performed their 2-year FU visit and have been analyzed clinically and radiologically. Clinical outcomes (NDI, VAS, SF-36) and ROM measurements were analyzed pre-operatively and at the different post-operative time-points. Complications and re-operations were also assessed. Occurrences of heterotopic ossifications (HOs) and of adjacent disc degeneration radiographic changes have been analyzed from 2-year FU X-rays. The mean NDI and VAS scores for arm and neck are reduced significantly at each post-operative time-point compared to pre-operative condition. Motion is preserved over the time at index levels (mean ROM = 9° at 2 years) and 85.5% of the segments are mobile at 2 years. HOs are responsible for the fusion of 6/76 levels at 2 years. However, presence of HO does not alter the clinical outcomes. The occurrence rate of radiological signs of ALD is very low at 2 years (9.1%). There has been no subsidence, no expulsion and no sub-luxation of the implant. Finally, after 2 years, 91% of the patients assume that they would undergo the procedure again. These intermediate

  2. Bactercline®-coated implants: Clinical results up to 1 year after loading from a controlled clinical trial

    PubMed Central

    Carinci, Francesco; Grecchi, Emma; Bignozzi, Carlo Alberto; Murmura, Giovanna; Piattelli, Adriano; Scarano, Antonio

    2012-01-01

    Background: Titanium dioxide exists in three different crystal lattices, anatase, rutile, and brookite. Anatase coating releases, under ultraviolet (UV) irradiation, free radicals such as ·OH, O2-, HO2-, and H2O2. This potent oxidizing power characteristically results in the lysis of bacteria and other organic substances. The purpose of this study was to evaluate the bone response to implants made of titanium alloy or coated with a new combination of anatase and Bactercline® product. Materials and Methods: In the period between July 2009 and June 2010, 26 patients (10 females and 16 males; median age 51 ± 11 years, min. 27 years, max. 72 years) were operated and 62 implants were inserted. Lost fixtures and peri-implant bone resorption were considered as predictors of clinical outcomes. Pearson χ2-test was used. Prosthesis and implant failures, any complications after loading, and peri-implant marginal bone-level changes were assessed by a masked assessor. All patients were followed up to 1 year after loading. Results: No implant was lost. Average bone resorption around implant was 0.33 mm (both for 25 standard and 37 Bactercline-coated implants), and thus no statistical difference was detected. Conclusion: These results shown that no adverse effects on osseo-integration were present. PMID:23814572

  3. Oxford phase 3 unicompartmental knee arthroplasty in Japan--clinical results in greater than one thousand cases over ten years.

    PubMed

    Yoshida, Kenjiro; Tada, Masahiro; Yoshida, Hirokazu; Takei, Satoshi; Fukuoka, Shinichi; Nakamura, Hiroaki

    2013-10-01

    There are few reports of the Oxford unicompartmental knee arthroplasty (UKA) survival rate in Asia. This study describes outcomes of 1279 Oxford UKAs for Japanese patients. The mean follow-up was 5.2 years. We divided patients into two groups based on preoperative indications (extended indications group and strict indications group). The Oxford knee score improved from 22.3 to 40.8 (P=0.041). The 10-year survival rate using revision was 95%. A total of 25 UKAs (2.0%) required revision. The most common reason was subsidence of tibial component. The 5-year cumulative survival rate of the strict indications group was significantly higher than that of the extended indications group (99.1% vs. 93.8%, P<0.001). When we followed inclusion criteria strictly, good clinical results were achieved in Asia.

  4. Results from the second year of operation of the Federal Methanol Fleet at Oak Ridge National Laboratory

    SciTech Connect

    West, B.H.; McGill ); Hillis, S.L. )

    1990-09-01

    The Oak Ridge National Laboratory has completed its second year of operation of ten vehicles for the Federal Methanol Fleet Project; five of the vehicles are fueled with methanol. Over 56,000 miles were accumulated on the vehicles in the second year bringing the total to over 152,000 miles. Energy consumption for the methanol cars was slightly higher than that of the gasoline cars again this year, most likely as a result of shorter average trip lengths for the methanol gas. Iron and lead have accumulated at greater rates in the lubricating oil of the methanol cars. Driver's ratings of vehicles reflected some dissatisfaction with the cold-weather performance of the methanol cars, but the cars have no special provisions for cold weather starting, and the fuel vapor pressure has not been tailored to the season as at other test sites. Otherwise, drivers' opinions of the methanol cars have been favorable. 13 refs., 4 figs., 10 tabs.

  5. A comparison of student performance in a simulation clinic and a traditional laboratory environment: three-year results.

    PubMed

    Clancy, James M S; Lindquist, Terry J; Palik, Joyce F; Johnson, Lynn A

    2002-12-01

    significant for the tooth prepared on the bench top (p = 0.0482), but it was not significant for the tooth prepared in the manikin (p = 0.2968). For Year 3 (two years of simulation clinic experience), the amount of elapsed time following completion of the fixed prosthodontic course was not significant for the tooth prepared on the bench top or in the manikin (p = 0.7275 and 0.6007). The questionnaire revealed that, in general, the majority of the students perceived their clinical readiness as more than adequate. These results are mixed in that students with more bench top experience scored better on the bench top, and students with more manikin experience scored equally in both environments.

  6. Randomized Clinical Trial of a Self-Adhering Flowable Composite for Class I Restorations: 2-Year Results

    PubMed Central

    Dagher, S.; El Osta, N.; Souhaid, P.

    2017-01-01

    Objectives. To compare the clinical performances of a self-adhering resin composite and a conventional flowable composite with a self-etch bonding system on permanent molars. The influence of using rubber dam versus cotton roll isolation was also investigated. Materials and Methods. Patients aged between 6 and 12 years and presenting at least two permanent molars in need of small class I restorations were selected. Thirty-four pairs of restorations were randomly placed by the same operator. Fifteen patients were treated under rubber dam and nineteen using cotton rolls isolation and saliva ejector. They were evaluated according to the modified USPHS criteria at baseline, 6 months, and 1 and 2 years by two independent evaluators. Results. All patients attended the two-year recall. For all measured variables, there was no significant difference between rubber dam and cotton after 2 years of restoration with Premise Flowable or Vertise Flow (p value > 0.05). The percentage of restorations scored alpha decreased significantly over time with Premise Flowable and Vertise Flow for marginal adaptation and surface texture as well as marginal discoloration while it did not vary significantly for color matching. After 2 years, Vertise Flow showed a similar behaviour to the Premise Flowable used with a self-adhesive resin system. PMID:28348594

  7. Long-Term Efficacy and Safety Profile of Lanthanum Carbonate: Results for up to 6 Years of Treatment

    PubMed Central

    Hutchison, Alastair J.; Barnett, M. Edwina; Krause, Rolfdieter; Kwan, Jonathan T.C.; Siami, Ghodrat A.

    2008-01-01

    Background/Aims Lanthanum carbonate (LC, FOSRENOL®) is an effective phosphate binder for which tolerability and a safety profile have been reported in haemodialysis patients. Patients from previous studies entered a 2-year extension, enabling assessment of efficacy and safety for up to 6 years of LC monotherapy. Methods Patients from four previous trials entered this study. Results Ninety-three patients started the extension, with 22 entering a sixth year of LC treatment. Two-thirds of all patients received LC doses of 2,250 or 3,000 mg/day. Reductions in serum phosphate and calcium × phosphate product were maintained for up to 6 years. There were no new or unexpected adverse events (AEs), and no increase in the incidence of events with increasing treatment exposure. Over the complete duration of therapy, treatment-related AEs occurred in 25.8% of patients and were primarily gastrointestinal in nature. No clinically relevant changes in liver function tests were observed and there was no evidence of adverse effects on the liver, bone or the central nervous system. Conclusions LC monotherapy was effective and well tolerated for up to 6 years with no evidence of safety concerns or increased frequency of AEs. PMID:18667837

  8. Testing aggregation hypotheses among Neotropical trees and shrubs: results from a 50-ha plot over 20 years of sampling.

    PubMed

    Myster, Randall W; Malahy, Michael P

    2012-09-01

    Spatial patterns of tropical trees and shrubs are important to understanding their interaction and the resultant structure of tropical rainforests. To assess this issue, we took advantage of previously collected data, on Neotropical tree and shrub stem identified to species and mapped for spatial coordinates in a 50ha plot, with a frequency of every five years and over a 20 year period. These stems data were first placed into four groups, regardless of species, depending on their location in the vertical strata of the rainforest (shrubs, understory trees, mid-sized trees, tall trees) and then used to generate aggregation patterns for each sampling year. We found shrubs and understory trees clumped at small spatial scales of a few meters for several of the years sampled. Alternatively, mid-sized trees and tall trees did not clump, nor did they show uniform (regular) patterns, during any sampling period. In general (1) groups found higher in the canopy did not show aggregation on the ground and (2) the spatial patterns of all four groups showed similarity among different sampling years, thereby supporting a "shifting mosaic" view of plant communities over large areas. Spatial analysis, such as this one, are critical to understanding and predicting tree spaces, tree-tree replacements and the Neotropical forest patterns, such as biodiversity and those needed for sustainability efforts, they produce.

  9. Geology of Libya Montes and the Interbasin Plains of Northern Tyrrhena Terra, Mars: First Year Results and Second Year Work Plan

    NASA Technical Reports Server (NTRS)

    Skinner, J. A., Jr.; Rogers, A. D.; Seelos, K. D.

    2010-01-01

    The Libya Montes-Tyrrhena Terra highland-lowland transitional zone of Mars is a complex tectonic and erosional region that contains some of the oldest exposed materials on the Martian surface as well as aqueous mineral signatures that may be potential chemical artifacts of early highland formational processes. Our 1:1M scale mapping project includes the geologic materials and landforms contained within MTMs 00282, -05282, -10282, 00277, - 05277, and -10277, which cover the highland portion of the transitional zone. The map region extends from the Libya Montes southward into Tyrrhena Terra and to the northern rim of Hellas basin and includes volcanic rocks of Syrtis Major Planum and a broad lowlying plain (palus) that forms a topographic divide between Isidis and Hellas basins. The objective of this project is to describe the geologic history of regional massif and plains materials by combining geomorphological and compositional mapping observations. This abstract summarizes the technical approaches and interim scientific results of Year 1 efforts and the expected work plan for Year 2 efforts.

  10. EVALUATION OF THE RESULTS FROM ARTHROSCOPIC REPAIR ON ROTATOR CUFF INJURIES AMONG PATIENTS UNDER 50 YEARS OF AGE

    PubMed Central

    Miyazaki, Alberto Naoki; Fregoneze, Marcelo; Santos, Pedro Doneux; da Silva, Luciana Andrade; do Val Sella, Guilherme; Santos, Ruy Mesquita Maranhão; de Souza, Adriano; Checchia, Sérgio Luiz

    2015-01-01

    Objective: To assess the results from arthroscopic surgical treatment of rotator cuff injuries among patients under 50 years of age. Methods: Sixty-three patients with rotator cuff injuries who underwent arthroscopic surgical treatment performed by the Shoulder and Elbow Group of the Department of Orthopedics and Traumatology, in the Fernandinho Simonsen wing of Santa Casa Medical School, São Paulo, between August 1998 and December 2007, were reassessed. The study included all patients with rotator cuff injuries who were under 50 years of age and had been followed up postoperatively for at least 24 months. Results: According to the UCLA evaluation criteria, 59 patients (92%) showed excellent and good results; five (8%) showed fair results; and none showed poor results. The postoperative evaluation showed that the mean range of motion was 145° for elevation, 47° for lateral rotation and T10 for medial rotation. Unsatisfactory results were associated with prolonged duration of the injury, with a statistically significant relationship. Conclusion: Arthroscopic repair of rotator cuff injuries in young patients produces excellent or good results for most patients. PMID:27047819

  11. Sustainable permaculture systems demonstration in the high mountain desert region of New Mexico -- results of three years practice

    SciTech Connect

    Lawrence, V.

    1995-11-01

    This paper reports on three years of results in the Permaculture restoration of a mountain drylands ranch outside Santa Fe, New Mexico which receives less than 11 inches rainfall/year. Dramatic results have been produced in the areas of erosion control, pastureland restoration, wild species propagation, aquaculture, riparian zone (wetland) restoration, edible landscape design and installation methodologies. Additionally, significant work has been performed in the area of youth education and community development. Current work includes a grant-financed (US Fish and Wildlife Service ``Partners for Wildlife`` Program) replanting and redevelopment of the entire riparian zone of the ranch and the design and development of a trout-spawning pond system that is self contained and self-purifying, with circulation through a structured wetland provided by a photovoltaic pumping system. This paper presents the design philosophy, overall design strategy and significant details of specific strategies, projects, and systems.

  12. Idaho's surface-water-quality monitoring program: results from five sites sampled during water years 1990-93

    USGS Publications Warehouse

    ,

    1994-01-01

    In 1990, the U.S. Geological Survey (USGS), in cooperation with the Idaho Department of Health and Welfare, Division of Environmental Quality, implemented a statewide water-quality monitoring program in response to Idaho's antidegradation policy as required by the Clean Water Act. The program objective is to provide water-quality managers with a coordinated statewide network to detect trends in surface-water quality. The monitoring program includes the collection and analysis of samples from 56 sites on the Bear, Clearwater, Kootenai, Pend Oreille, Salmon, Snake, and Spokane Rivers and their tributaries (fig. 1). Samples are collected every year at 5 sites (annual sites) in drainage basins where long-term water-quality management is practiced, every other year at 19 sites (biennial sites) in basins where land and water uses change slowly, and every third year at 32 sites (triennial sites) where future development may affect water quality. Each year, 25 of the 56 sites are sampled. This report discusses results of sampling at five annual sites. During water years 1990-93 (October 1, 1989, through September 30, 1993), samples were collected six times per year at the five annual sites (fig. 1). Onsite analyses were made for discharge, specific conductance, pH, temperature, dissolved oxygen, bacteria (fecal coliform and fecal streptococci), and alkalinity. Laboratory analyses were made for major ions, nutrients, trace elements, and suspended sediment. Suspended sediment, nitrate, fecal coliform, trace elements, and specific conductance were used to characterize surface-water quality. Because concentrations of all trace elements except zinc were near detection limits, only zinc is discussed.

  13. Treatment of non-traumatic rotator cuff tears: A randomised controlled trial with one-year clinical results.

    PubMed

    Kukkonen, J; Joukainen, A; Lehtinen, J; Mattila, K T; Tuominen, E K J; Kauko, T; Aärimaa, V

    2014-01-01

    We have compared three different methods of treating symptomatic non-traumatic tears of the supraspinatus tendon in patients above 55 years of age. A total of 180 shoulders (173 patients) with supraspinatus tendon tears were randomly allocated into one of three groups (each of 60 shoulders); physiotherapy (group 1), acromioplasty and physiotherapy (group 2) and rotator cuff repair, acromioplasty and physiotherapy (group 3). The Constant score was assessed and followed up by an independent observer pre-operatively and at three, six and twelve months after the intervention. Of these, 167 shoulders were available for assessment at one year (follow-up rate of 92.8%). There were 55 shoulders in group 1 (24 in males and 31 in females, mean age 65 years (55 to 79)), 57 in group 2 (29 male and 28 female, mean age 65 years (55 to 79)) and 55 shoulders in group 3 (26 male and 29 female, mean age 65 years (55 to 81)). There were no between-group differences in the Constant score at final follow-up: 74.1 (sd 14.2), 77.2 (sd 13.0) and 77.9 (sd 12.1) in groups 1, 2 and 3, respectively (p = 0.34). The mean change in the Constant score was 17.0, 17.5, and 19.8, respectively (p = 0.34). These results suggest that at one-year follow-up, operative treatment is no better than conservative treatment with regard to non-traumatic supraspinatus tears, and that conservative treatment should be considered as the primary method of treatment for this condition.

  14. Carotid Stenting with Distal Protection in High-Surgical-Risk Patients: One-Year Results of the ASTI Trial

    SciTech Connect

    Bosiers, Marc; Scheinert, Dierk; Mathias, Klaus; Langhoff, Ralf; Mudra, Harald; Diaz-Cartelle, Juan

    2015-04-15

    PurposeThis prospective, multicenter, nonrandomized study evaluated the periprocedural and 1-year outcomes in high-surgical-risk patients with carotid artery stenosis treated with the Adapt Carotid Stent plus FilterWire EZ distal protection catheter (Boston Scientific Corporation, Natick, MA).Materials and MethodsThe study enrolled 100 patients (32 symptomatic, 63 asymptomatic, 5 unknown) at high risk for carotid endarterectomy due to prespecified anatomical criteria and/or medical comorbidities. Thirty-day and 1-year follow-up included clinical evaluation, carotid duplex ultrasound, and independent neurologic and NIH stroke scale assessments. One-year endpoints included the composite rate of major adverse events (MAE), defined as death, stroke, and myocardial infarction (MI) and the rates of late ipsilateral stroke (31–365 days), target lesion revascularization, and in-stent restenosis.ResultsOf the 100 enrolled patients, technical success was achieved in 90.9 % (90/99). The 30-day MAE rate (5.1 %) consisted of major stroke (2.0 %) and minor stroke (3.1 %); no deaths or MIs occurred. The 1-year MAE rate (12.2 %) consisted of death, MI, and stroke rates of 4.4, 3.3, and 8.9 %, respectively. Late ipsilateral stroke (31–365 days) rate was 1.1 %. Symptomatic patients had higher rates of death (11.1 vs. 1.7 %) and MI (7.4 vs. 1.7 %), but lower rates of major (7.4 vs. 10.0 %) and minor stroke (0.0 vs. 6.7 %), compared with asymptomatic patients.ConclusionResults through 1 year postprocedure demonstrated that carotid artery stenting with Adapt Carotid Stent and FilterWire EZ is safe and effective in high-risk-surgical patients.

  15. Peri-implant evaluation of osseointegrated implants subjected to orthodontic forces: results after three years of functional loading

    PubMed Central

    Marins, Bruna de Rezende; Pramiu, Suy Ellen; Busato, Mauro Carlos Agner; Marchi, Luiz Carlos; Togashi, Adriane Yaeko

    2016-01-01

    ABSTRACT Objective: The objective of this study was to clinically and radiographically assess the peri-implant conditions of implants used as orthodontic anchorage. Methods: Two groups were studied: 1) a test group in which osseointegrated implants were used as orthodontic anchorage, with the application of 200-cN force; and 2) a control group in which implants were not subjected to orthodontic force, but supported a screw-retained prosthesis. Clinical evaluations were performed three, six and nine months after prosthesis installation and 1- and 3-year follow-up examinations. Intraoral periapical radiographs were obtained 30 days after surgical implant placement, at the time of prosthesis installation, and one, two and three years thereafter. The results were compared by Kruskal-Wallis test. Results: There was no statistically significant difference in clinical probing depth (p = 0.1078) or mesial and distal crestal bone resorption (p = 0.1832) during the study period. After three years of follow-up, the mean probing depth was 2.21 mm for the control group and 2.39 mm for the test group. The implants of the control group showed a mean distance between the bone crest and implant shoulder of 2.39 mm, whereas the implants used as orthodontic anchorage showed a mean distance of 2.58 mm at the distal site. Conclusion: Results suggest that the use of stable intraoral orthodontic anchorage did not compromise the health of peri-implant tissues or the longevity of the implant. PMID:27275618

  16. Preventing Alcohol Use Among Late Adolescent Urban Youth: 6-Year Results From a Computer-Based Intervention*

    PubMed Central

    Schwinn, Traci M.; Schinke, Steven P.

    2010-01-01

    Objective: This study was undertaken to evaluate the efficacy of a skills-based CD-ROM intervention, with and without a parent component, to reduce alcohol use among urban youth at 6-year follow-up. Method: At recruitment, 513 youths with a mean age of 10.8 years were randomly assigned to one of three study arms: youth CD-ROM intervention plus parent component, youth CD-ROM intervention only, or control. All youths completed pretest, posttest, and annual follow-up measures. Youths and parents in their respective arms received the initial intervention program between pretest and posttest measures and received booster interventions between each follow-up measure. Results: With 80% sample retention at 6-year follow-up, youths in both intervention arms reported less past-month alcohol and cigarette use and fewer instances of heavy drinking and negative alcohol-related consequences. Despite having similar numbers of drinking peers as youths in the control arm, youths in both intervention arms reported greater alcohol-refusal skills. Only past-month cigarette use differed between the two intervention arms, with youths in the intervention-plus-parent-component arm smoking less than youths in the CD-ROM intervention-only arm. Conclusions: Six years after initial intervention, youths who received a culturally tailored, skills-based prevention program had reduced alcohol use and lower rates of related risky behaviors than youths in the control arm. PMID:20553661

  17. Deferiprone versus deferoxamine in thalassemia intermedia: Results from a 5-year long-term Italian multicenter randomized clinical trial.

    PubMed

    Calvaruso, Giuseppina; Vitrano, Angela; Di Maggio, Rosario; Lai, Eliana; Colletta, Grazia; Quota, Alessandra; Gerardi, Calogera; Rigoli, Luciana Concetta; Sacco, Massimiliano; Pitrolo, Lorella; Maggio, Aurelio

    2015-07-01

    In patients with thalassemia intermedia (TI), such as beta-TI, alpha-thalassemia (mainly HbH disease and mild/moderate forms of HbE/beta-thalassemia), iron overload is an important challenge in terms of diagnosis, monitoring, and treatment. Moreover, to date, the only possible chelators available are deferoxamine, deferasirox, and deferiprone. Here, we report the first 5-year long-term randomized clinical trial comparing the effectiveness of deferiprone versus deferoxamine in patients with TI. Body iron burden, which was determined by measuring serum ferritin levels in the same patient over 5 years and analyzed according to the generalized linear mixed model (GLMM), showed a linear decrease over time in the mean serum ferritin levels in both treatment groups (P-value = 0.035). The overall period of observation was 235.2 person-years for the deferiprone patients compared with 214.3 person-years for the deferoxamine patients. The results of the log-rank test suggested that the deferiprone treatment did not affect survival compared with the deferoxamine treatment (P-value = 0.360). The major adverse events observed included gastrointestinal symptoms and joint pain or arthralgia. Neutropenia and agranulocytosis were also detected, suggesting needing of strict hematological control. In conclusion, long-term iron chelation therapy with deferiprone is associated with an efficacy and safety similar to that of deferoxamine, suggesting that this drug is an alternative option in cases in which deferoxamine and deferasirox are contraindicated.

  18. Time trends in socioeconomic inequalities in cancer mortality: results from a 35 year prospective study in British men

    PubMed Central

    2014-01-01

    Background Socioeconomic inequalities in cancer mortality in Britain have been shown to be present in the 1990s and early 2000s. Little is known about on-going patterns in such inequalities in cancer mortality. We examined time trends in socioeconomic inequalities in cancer mortality in Britain between 1978 and 2013. Methods A socially representative cohort of 7489 British men with data on longest-held occupational social class, followed up for 35 years, in whom 1484 cancer deaths occurred. Results The hazard ratio for cancer mortality for manual vs. non-manual social classes remained unchanged; among men aged 50–59 years it was 1.62 (95%CI 1.17–2.24) between 1980–1990 and 1.65 (95%CI 1.14–2.40) between 1990–2000. The absolute difference (non-manual minus manual) in probability of surviving death from cancer to 70 years remained at 3% over the follow-up. The consistency of risks over time was similar for both smoking-related and non-smoking related cancer mortality. Conclusion Socioeconomic inequalities in cancer mortality in Britain remain unchanged over the last 35 years and need to be urgently addressed. PMID:24975430

  19. Effect of a fish oil diet on asthma: results of a 1-year double-blind study.

    PubMed

    Dry, J; Vincent, D

    1991-01-01

    Airway inflammation is a major component of asthma. Food intake of N-3 fatty acids (FA) is associated with a low incidence of inflammatory diseases, such as asthma. We treated 12 asthmatic patients with FA and report the positive results of this 1-year double-blind study. A positive effect on forced expiratory volume in 1 s was observed after the 9 month of treatment. Our results are in favor of the use of FA, but have to be confirmed by other studies.

  20. Results from three years of the world's largest interlaboratory comparison for total mercury and methylmercury: Method performance and best practices

    NASA Astrophysics Data System (ADS)

    Creswell, J. E.; Engel, V.; Carter, A.; Davies, C.

    2013-12-01

    Brooks Rand Instruments has conducted the world's largest interlaboratory comparison study for total mercury and methylmercury in natural waters annually for three years. Each year, roughly 50 laboratories registered to participate and the majority of participants submitted results. Each laboratory was assigned a performance score based on the distance between its results and the consensus mean, as well as the precision of its replicate analyses. Participants were also asked to provide detailed data on their analytical methodology and equipment. We used the methodology data and performance scores to assess the performance of the various methods reported and equipment used. Although the majority of methods in use show no systematic trend toward poor analytical performance, there are noteworthy exceptions. We present results from each of the three years of the interlaboratory comparison exercise, as well as aggregated method performance data. We compare the methods used in this study to methods from other published interlaboratory comparison studies and present a list of recommended best practices. Our goals in creating a list of best practices are to maximize participation, ensure inclusiveness, minimize non-response bias, guarantee high data quality, and promote transparency of analysis. We seek to create a standardized methodology for interlaboratory comparison exercises for total mercury and methylmercury analysis in water, which will lead to more directly comparable results between studies. We show that in most cases, the coefficient of variation between labs measuring replicates of the same sample is greater than 20% after the removal of outlying data points (e.g. Figure 1). It is difficult to make comparisons between studies and ecosystems with such a high variability between labs. We highlight the need for regular participation in interlaboratory comparison studies and continuous analytical method improvement in order to ensure accurate data. Figure 1

  1. Lung cancer and dust exposure: results of a prospective cohort study following 3260 workers for 50 years

    PubMed Central

    Moshammer, H; Neuberger, M

    2004-01-01

    Aims: To study the lasting health impact of occupational dust exposure on life expectancy and specific causes of death. Methods: Male Viennese workers, selected at age ⩾40 (mean 54) years during preventive check-ups between 1950 and 1960, were followed prospectively until death. Half of them (1630) were exposed at work to (non-fibrous) particulates, while the non-exposed workers were matched for year, age, and smoking status at the start of observation. Results: Average life expectancy of those exposed was 1.6 years less than that of those non-exposed. Only a small part of this decrease in life expectancy (hazards ratios in brackets) was related to acknowledged occupational diseases such as silicosis and silicotuberculosis (67.12). Chronic obstructive lung disease (1.82) and cancer of the lung (1.42) and stomach (1.77) were found more frequently among those exposed. Conclusions: Results support the hypothesis that high exposure to insoluble particulates such as silica in the metal, glass, ceramics, and stone industries promotes bronchial cancer and chronic obstructive pulmonary disease. The finding of an increased incidence of stomach cancer might be related to particles swallowed after clearance from the airways. PMID:14739382

  2. Integration of family planning services into HIV care clinics: Results one year after a cluster randomized controlled trial in Kenya

    PubMed Central

    Cohen, Craig R.; Grossman, Daniel; Onono, Maricianah; Blat, Cinthia; Newmann, Sara J.; Burger, Rachel L.; Shade, Starley B.; Bett, Norah; Bukusi, Elizabeth A.

    2017-01-01

    Objectives To determine if integration of family planning (FP) and HIV services led to increased use of more effective contraception (i.e. hormonal and permanent methods, and intrauterine devices) and decreased pregnancy rates. Design Cohort analysis following cluster randomized trial, when the Kenya Ministry of Health led integration of the remaining control (delayed integration) sites and oversaw integrated services at the original intervention (early integration) sites. Setting Eighteen health facilities in Kenya. Subjects Women aged 18–45 receiving care: 5682 encounters at baseline, and 11628 encounters during the fourth quarter of year 2. Intervention “One-stop shop” approach to integrating FP and HIV services. Main outcome measures Use of more effective contraceptive methods and incident pregnancy across two years of follow-up. Results Following integration of FP and HIV services at the six delayed integration clinics, use of more effective contraception increased from 31.7% to 44.2% of encounters (+12.5%; Prevalence ratio (PR) = 1.39 (1.19–1.63). Among the twelve early integration sites, the proportion of encounters at which women used more effective contraceptive methods was sustained from the end of the first to the second year of follow-up (37.5% vs. 37.0%). Pregnancy incidence including all 18 integrated sites in year two declined in comparison to the control arm in year one (rate ratio: 0.72; 95% CI 0.60–0.87). Conclusions Integration of FP services into HIV clinics led to a sustained increase in the use of more effective contraceptives and decrease in pregnancy incidence 24 months following implementation of the integrated service model. Trial registration ClinicalTrials.gov NCT01001507 PMID:28328966

  3. Intensive Weight Loss Intervention in Individuals Ages 65 Years or Older: Results from the Look AHEAD Type 2 Diabetes Trial

    PubMed Central

    Espeland, Mark A.; Rejeski, W. Jack; West, Delia S.; Bray, George A.; Clark, Jeanne M.; Peters, Anne L.; Chen, Haiying; Johnson, Karen C.; Horton, Edward S.; Hazuda, Helen P.

    2013-01-01

    OBJECTIVES To compare the relative effects of four years of intensive lifestyle intervention on weight, fitness, and cardiovascular disease risk factors among older versus younger individuals DESIGN A randomized controlled clinical trial SETTING 16 US clinical sites PARTICIPANTS Individuals with type 2 diabetes: 1,053 aged 65–76 years and 4,092 aged 45–64 years INTERVENTIONS An intensive behavioral intervention designed to promote and maintain weight loss through caloric restriction and increased physical activity compared to a condition of diabetes support and education. MEASUREMENTS Standardized assessments of weight, fitness (based on graded exercise testing), and cardiovascular disease risk factors RESULTS Across four years, older individuals had greater intervention-related mean weight losses than younger participants, 6.2% versus 5.1% (interaction p=0.006) and comparable relative mean increases in fitness, 0.56 versus 0.53 metabolic equivalents (interaction p=0.72). These benefits were seen consistently across subgroups of older adults formed by many demographic and health factors. Among a panel of age-related health conditions, only self-reported worsening vision was associated with poorer intervention-related weight loss in older individuals. The intensive lifestyle intervention produced mean increases in high density lipoprotein cholesterol (2.03 mg/dl; p<0.001) and decreases in glycated hemoglobin (0.21%; p<0.001) and waist girth (3.52 cc; p<0.001) across 4 years that were at least as large in older compared to younger individuals. CONCLUSION Intensive lifestyle intervention targeting weight loss and increased physical activity is effective in overweight and obese older individuals to produce sustained weight loss and improvements in fitness and cardiovascular risk factors. PMID:23668423

  4. Recovery Potential of a Western Lowland Gorilla Population following a Major Ebola Outbreak: Results from a Ten Year Study

    PubMed Central

    Gatti, Sylvain; Levréro, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sébastien; Ménard, Nelly

    2012-01-01

    Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla

  5. The Harris-Galante cementless acetabular component: results in 190 cases with at least 3 years follow-up.

    PubMed

    Claus, B; Van Innis, B; De Witte, E; Van Overschelde, J; Magotteaux, B; Fatemi, F; Vandepaer, F

    1993-01-01

    The results of 190 primary total hip arthroplasties with a Harris-Galante cementless acetabular cup were reviewed. All patients had a minimum follow-up of 3 years (range, 3 to 5.5 years, mean 46 months). Clinical and radiographical analysis was performed. Inguinal pain was recorded in five cases. We noted a fracture of a screw in four cases without further implications. There was no evidence of acetabular loosening. There was no migration of the acetabular cup. No acetabular component showed measurable wear of the polyethylene liner. Non-progressive radiolucent lines were recorded in 14% of the patients: among these patients, radiolucent lines were noted in zone 1 in 46%, in zone 2 in 4% and in zone 3 in 86%. Two socket revisions became necessary. One patient suffered a deep-seated infection. Another revision was necessary because of recurrent dislocation.

  6. [Nine-Year Experience after ISO 15189 Acquisition, How Successful was It? Focusing on the Results of Interviews and Questionnaires].

    PubMed

    Fujimoto, Kazumitsu; Asai, Noriaki; Nakajima, Yoshinaga; Inoue, Kaoru

    2015-11-01

    Our laboratory, for the purpose of Quality Management System (QMS) improvement, acquired ISO 15189:2003 accreditation 9 years ago and completed the renewal to ISO 15189:2012 last year. In this study, we reviewed the efficacy of ISO 15189 based on an analysis of laboratory director's and managers' opinions. We could realize QMS improvement through the proactive implementation of preventive and corrective actions, and also the continuous implementation of education and delivery by means of reviewing the interview records of ISO 15189:2012 renewal with the laboratory director. All answers to the questionnaire obtained from managers with regard to the advantages of ISO 15189 acquisition agreed with the purpose of ISO 15189. From these results, we concluded that ISO 15189 acquisition was successful for QMS improvement. [Review].

  7. IceCube results from point-like source searches using 6 years of through-going muon data

    NASA Astrophysics Data System (ADS)

    Coenders, Stefan

    2016-04-01

    The IceCube Neutrino Observatory located at the geographic South Pole was designed to study and discover high energy neutrinos coming from both galactic and extra-galactic astrophysical sources. Track-like events induced by charged-current muon-neutrino interactions close to the IceCube detector give an angular resolution better than 1∘ above TeV energies. We present here the results of searches for point-like astrophysical neutrino sources on the full sky using 6 years of detector livetime, of which three years use the complete IceCube detector. Within 2000 days of detector livetime, IceCube is sensitive to a steady flux substantially below E2∂ϕ/∂E = 10-12 TeV cm-2 s-1 in the northern sky for neutrino energies above 10 TeV.

  8. Impacts of climate change on Middle Eastern societies over the last 2700 years: new results from the Gejkar speleothem, Iraq

    NASA Astrophysics Data System (ADS)

    Flohr, Pascal; Fleitmann, Dominik; Bosomworth, Matt; Cheng, Hai; Sadekov, Aleksey; Matthews, Roger; Matthews, Wendy; Black, Stuart; Edwards, Lawrence

    2016-04-01

    Climatic and environmental changes are often cited as a major factor for past social, economic, and political changes. This is especially relevant in the semi-arid to arid Middle East, where, however, only few precisely dated, high-resolution climate records are available. Here we present new results from an up to annually resolved stalagmite from Gejkar Cave in the Kurdish Regional Government of Iraq region. Based on Uranium-series dating and annual layer counts, the record dates back ~2700 years, and its annual layer thickness and carbon and oxygen isotope profile appear indicative of precipitation and effective moisture. We also assess if observed decadal to multi-decadal shifts in precipitation are synchronous with socio-economic changes as observed in the archaeological and historical record in the wider Middle East over the last 2000 years, such as the largely prosperous Roman and Byzantine periods, the Seljuq invasion, and the decline of the Ottoman Empire.

  9. On determining the spectrum of primordial inhomogeneity from the COBE DMR sky maps: Results of two-year data analysis

    NASA Technical Reports Server (NTRS)

    Gorski, K. M.; Hinshaw, G.; Banday, A. J.; Bennett, C. L.; Wright, E. L.; Kogut, A.; Smoot, G. F.; Lubin, P.

    1994-01-01

    A new technique of Fourier analysis on a cut sky has been applied to the two-year Cosmic Background Explorer (COBE) Differential Microwave Radiometer (DMR) 53 and 90 GHz sky maps. The Bayesian power spectrum estimation results are consistent with the Harrison-Zel'dovich n = 1 model. The maximum likelihood estimates of the usual parameters defining the power spectrum of primordial perturbations are n = 1.22 (1.02) and Q(sub rms-PS) = 17 (20) microK including (excluding) the quadrupole. A spectral-index-independent normalization is naturally expressed for the two-year maps in terms of the multipole amplitude a(sub 9) = 8.2 (8.3) microK (to approximately 12 sigma significance). The marginal likelihood function on n obtained by intergration with respect to a(sub 9) renders n = 1.17 +/- 0.31 (0.96 +/- 0.36).

  10. Treatment of focal degenerative cartilage defects with polymer-based autologous chondrocyte grafts: four-year clinical results

    PubMed Central

    Kreuz, Peter C; Müller, Sebastian; Ossendorf, Christian; Kaps, Christian; Erggelet, Christoph

    2009-01-01

    Introduction Second-generation autologous chondrocyte implantation with scaffolds stabilizing the grafts is a clinically effective procedure for cartilage repair. In this ongoing prospective observational case report study, we evaluated the effectiveness of BioSeed®-C, a cell-based cartilage graft based on autologous chondrocytes embedded in fibrin and a stable resorbable polymer scaffold, for the treatment of clinical symptomatic focal degenerative defects of the knee. Methods Clinical outcome after 4-year clinical follow-up was assessed in 19 patients with preoperatively radiologically confirmed osteoarthritis and a Kellgren-Lawrence score of 2 or more. Clinical scoring was performed before implantation of the graft and 6, 12, and 48 months after implantation using the Lysholm score, the Knee injury and Osteoarthritis Outcome Score (KOOS), the International Knee Documentation Committee (IKDC) score, and the International Cartilage Repair Society (ICRS) score. Cartilage regeneration and articular resurfacing were assessed by magnetic resonance imaging (MRI) 4 years after implantation of the autologous cartilage graft. Results Significant improvement (P < 0.05) of the Lysholm and ICRS scores was observed as early as 6 months after implantation of BioSeed®-C and remained stable during follow-up. The IKDC score showed significant improvement compared with the preoperative situation at 12 and 48 months (P < 0.05). The KOOS showed significant improvement in the subclasses pain, activities of daily living, and knee-related quality of life 6 months as well as 1 and 4 years after implantation of BioSeed®-C in osteoarthritic defects (P < 0.05). MRI analysis showed moderate to complete defect filling with a normal to incidentally hyperintense signal in 16 out of 19 patients treated with BioSeed®-C. Two patients without improvement in the clinical and MRI scores received a total knee endoprosthesis after 4 years. Conclusions The results show that the good clinical

  11. FFR guided PCI on long coronary lesions: 2-year clinical results with 2nd or newer generation DES

    PubMed Central

    Arvydas, Baranauskas; Vilhelmas, Bajoras; Povilas, Budrys; Aleksandras, Laucevičius; Giedrius, Davidavičius

    2016-01-01

    Background. Despite improvements in drug-eluting stent (DES) technology, treatment strategies for long coronary artery lesions remain a controversial issue. The aim of our study was to evaluate the long-term clinical results after FFR guided PCI on long coronary lesions. Materials and methods. A total of 74 consecutive patients with significant (mean FFR 0.61 ± 0.11) coronary artery lesions ≥30 mm in length were included in the prospective study. All patients were treated with FFR guided PCI implanting newer generation Biolimus, Everolimus or Zotarolimus eluting stents. Clinical endpoints – target vessel revascularization (TVR) and major adverse cardiac events (MACE) – were recorded at 1 and 2 years. Results. 100% angiographic procedure success was achieved, the mean post procedural FFR was 0.88 ± 0.06. At 2-year follow-up, 6 (8.1%) patients had ischemia driven TVR, all within the first 12 months. There were no target vessel related acute coronary syndromes and definite stent thromboses in the study group. At 2 years, the total MACE rate was 29.7%. There was a trend towards a higher TVR rate in patients with overlapping DES vs single DES implanted (9.6 vs 4.5%, p = 0.6). On regression analysis, the total stent length had no influence on the TVR rate. Conclusions. At 2 years after stenting long coronary lesions with newer generation DES the TVR rate was 8.1%, which is acceptable in the high cardiovascular risk population with diffuse coronary artery disease. The total stent length did not affect the long-term clinical outcomes. PMID:28356786

  12. Full-endoscopic technique for anterior cervical discectomy and interbody fusion: 5-year follow-up results of 67 cases.

    PubMed

    Yao, Nuzhao; Wang, Cheng; Wang, Wenjun; Wang, Lushan

    2011-06-01

    With minimally invasive technique becoming more popular, endoscopic operations such as arthroscopy or laparoscopy have become the standard of care in several other areas. In this study, we evaluated the 5-year follow-up outcomes of anterior cervical (Ahn et al. in Photomed Laser Surg 23:362-368, 2005) discectomy and interbody fusion (ACDF) performed via endoscopic approach. Sixty-seven patients who underwent anterior cervical discectomy and cage fusion performed using endoscopic technique were followed for at least 5 years. We reviewed the clinical and radiographic records of these patients. The postoperative radiographic measures accessed were the anterior intervertebral height (AIH) and the lordosis angle (LDA). Clinical outcomes were determined using the previously validated Japanese Orthopaedic Association (JOA) and the pain visual analog scale (VAS). Patients included had a minimal follow-up period of 5 years and based on the outcomes criteria (JOA, VAS), 86.6% of patients reported excellent or good results. The AIH increased on average 18.7% of the original height (p < 0.01), and the LDA were more physiologic at final follow-up. Of the 67 cases, there was no segmental instability, and the bone fusion rate was 100%. One patient required revision open ACDF due to adjacent segment disc herniation 6 years postoperatively. There were no intraoperative complications, dysphasia or esophageal injury in this study group. It indicated endoscopic technique for ACDF can obtain satisfactory results in patients with cervical disc herniation, cervical myelopathy, or radiculopathy. Compared with a traditional approach, this technique may be associated with less morbidity while improving cosmesis and postoperative recovery. Prospective randomized control trials are needed to directly compare these two procedures.

  13. Clinical evaluation on porcelain laminate veneers bonded with light-cured composite: results up to 7 years.

    PubMed

    D'Arcangelo, Camillo; De Angelis, Francesco; Vadini, Mirco; D'Amario, Maurizio

    2012-08-01

    The purpose of this study was to evaluate the clinical performance of laminate porcelain veneers bonded with a light-cured composite. Thirty patients were restored with 119 porcelain laminate veneers. The veneers were studied for an observation time of 7 years. Marginal adaptation, marginal discoloration, secondary caries, color match, and anatomic form were clinically examined following modified United States Public Health Service (USPHS) criteria. Each restoration was also examined for cracks, fractures, and debonding. Pulp vitality was verified. In addition, plaque and gingival indexes and increase in gingival recession were recorded. Survival rate evaluating absolute failures and success rate describing relative failures were statistically determined, using both restoration and patient-related analyses. On the basis of the criteria used, most of the veneers rated Alfa. After 7 years, the results of the clinical investigation regarding marginal adaptation and marginal discoloration revealed only 2.5% and 4.2% Bravo ratings, respectively, among the 119 initially placed veneers. Using the restoration as the statistical unit, the survival rate was 97.5%, with a high estimated success probability of 0.843 after 7 years. Using the patient as the statistical unit, the survival rate was 90.0% and the estimated success probability after 7 years was 0.824. Gingival response to the veneers was all in the satisfactory range. Porcelain laminate veneers offer a predictable and successful treatment modality giving a maximum preservation of sound tooth. The preparation, cementation, and finishing procedures adopted are considered key factors for the long-term success and aesthetical result of the veneer restorations.

  14. Pilot phase evaluation of the elective general practice class: results of student surveys of the first two years

    PubMed Central

    Samos, Franziska-Antonia; Heise, Marcus; Fuchs, Stephan; Mittmann, Susanne; Bauer, Alexander; Klement, Andreas

    2017-01-01

    Background: Primary health care in rural regions is currently undergoing a global crisis in respect of the next generation of practitioners. National and international recommendations advise placing greater emphasis upon practical skills and competences in medical studies. It is also in the interest of training the next generation to include mentoring and longitudinal integration of contact to teaching practices for general medicine in an early stage. Consequently, the General Practice Class (KAM) was introduced in Halle in 2011 as an elective with 20 individually mentored students per year, beginning with the first subject-related semester. We are now reporting on the results of the evaluation for the first two years. Method: A standardised online survey was carried out with all students who took part in the KAM in the two years 2011 and 2012 (N=38). For both years the survey was made at the end of the first summer semester on the basis of an adapted version of the Heidelberger Inventar zur Lehrevaluation (Heidelberg Inventory for the Evaluation of Teaching, HILVE-II) and the Berliner Evaluationsinstrument für selbsteingeschätzte, studentische Kompetenzen (Berlin Evaluation Instrument for the self-assessment of student competences, BEvaKomp). Furthermore, each year the preference for the choice of specialty and location of a medical practice was queried. Predictors for the preference of the chosen specialty and the location of a medical practice were estimated by binary logistic regression analysis. Via univariate evaluations the number of students who reported an increase in knowledge in different areas of competence as a result of the KAM was counted. Correlations between the intention to remain in the KAM and the quality of teaching were evaluated on the basis of bivariate correlations. Results: 48% of the students agreed partly or fully that the KAM seminars enhanced their specialist competence. This individual acquiring of competence in the model project

  15. Evidence for safety and efficacy of risedronate in men with osteoporosis over 4 years of treatment: Results from the 2-year, open-label, extension study of a 2-year, randomized, double-blind, placebo-controlled study.

    PubMed

    Boonen, Steven; Lorenc, Roman S; Wenderoth, Dietrich; Stoner, Karen J; Eusebio, Rachelle; Orwoll, Eric S

    2012-09-01

    A 2-year, randomized, double-blind, placebo-controlled study in men with osteoporosis demonstrated that treatment with risedronate 35mg once a week significantly decreased bone turnover markers (BTMs) and increased bone mineral density (BMD). This study was extended to include a 2-year, open-label extension to continue to assess the safety and efficacy of risedronate in men with osteoporosis. In the open-label extension, all patients received risedronate 35mg once a week, and 1000mg elemental calcium and 400 to 500IU vitamin D daily for up to 2 years. The safety of risedronate was evaluated based on adverse events, laboratory data, vital signs, and physical examination results. BMD, BTMs, and the incidence of new vertebral fractures were also assessed. A total of 218 (of 284) patients enrolled in the open-label extension. Risedronate continued to produce significant increases in lumbar spine BMD from baseline (7.87%) in the group of patients who took it for 4 years. Risedronate produced significant increases in lumbar spine BMD from baseline (6.27%) in the former placebo group who took it for 2 years during the open-label extension. Few new vertebral and clinical fractures occurred during the study. There were no significant differences in BTMs between the two groups at months 36 and 48. Incidences of any upper GI adverse events during the extension were low and similar in the two groups; however, the percent of moderate to severe events were higher (8% versus 2%) in the group that received placebo prior to the extension. Safety results continued to show that risedronate was well-tolerated in men with osteoporosis. Patients who received risedronate 35mg once a week for 2years in the open-label extension study showed similar safety and efficacy results compared with those who received risedronate treatment in the first 2 double-blind years of the study. Patients who received risedronate for 4 years in total showed similar safety and efficacy to that observed in

  16. Endogenous levels of nitrites and nitrates in wide consumption foodstuffs: Results of five years of official controls and monitoring.

    PubMed

    Iammarino, Marco; Di Taranto, Aurelia; Cristino, Marianna

    2013-10-15

    The massive introduction of nitrogen fertilisers, necessary to maximise the global food production, has brought about an increase of the residual amounts of nitrites and nitrates in the products. Notoriously, these compounds may exercise toxic effects. In this work the results obtained from 5years of official controls and monitoring focused on tracing quantifiable amounts of nitrites and nitrates in 1785 samples of meat, dairy, fish products and leafy vegetables are reported. A widespread presence of nitrates at low concentrations in foodstuffs was verified. High concentrations of nitrates were registered in some leafy vegetables and mussels samples, while high nitrites concentrations were registered in some spinach samples. The results confirmed the necessity to develop most controls and suggest the introduction of new legal limits related to some combinations contaminant/matrix. Such new limits may fill legislative gaps that may cause wrong interpretations of the results obtained during official controls.

  17. Randomized Controlled Trial of Forward-Planned Intensity Modulated Radiotherapy for Early Breast Cancer: Interim Results at 2 Years

    SciTech Connect

    Barnett, Gillian C.; Wilkinson, Jennifer S.; Moody, Anne M.; Wilson, Charles B.; Twyman, Nicola; Wishart, Gordon C.; Burnet, Neil G.; Coles, Charlotte E.

    2012-02-01

    Purpose: This single-center randomized trial was designed to investigate whether intensity-modulated radiotherapy (IMRT) reduces late toxicity in patients with early-stage breast cancer. Methods and Materials: The standard tangential plans of 1,145 nonselected patients were analyzed. The patients with inhomogeneous plans were randomized to a simple method of forward-planned IMRT or standard radiotherapy (RT). The primary endpoint was serial photographic assessment of breast shrinkage. Results: At 2 years, no significant difference was found in the development of any photographically assessed breast shrinkage between the patients randomized to the interventional or control group (odds ratio, 1.51; 95% confidence interval, 0.83-1.58; p = .41). The patients in the control group were more likely to develop telangiectasia than those in the IMRT group (odds ratio, 1.68; 95% confidence interval 1.13-2.40; p = .009). Poor baseline surgical cosmesis resulted in poor overall cosmesis at 2 years after RT. In patients who had good surgical cosmesis, those randomized to IMRT were less likely to deteriorate to a moderate or poor overall cosmesis than those in the control group (odds ratio, 0.63; 95% confidence interval, 0.39-1.03, p = .061). Conclusions: IMRT can lead to a significant reduction in telangiectasia at comparatively early follow-up of only 2 years after RT completion. An important component of breast induration and shrinkage will actually result from the surgery and not from the RT. Surgical cosmesis is an important determinant of overall cosmesis and could partially mask the longer term benefits of IMRT at this early stage.

  18. Bacterial profiling of Saharan dust deposition in the Atlantic Ocean using sediment trap moorings – year one results

    NASA Astrophysics Data System (ADS)

    Munday, Chris; Brummer, Geert-Jan; van der Does, Michelle; Korte, Laura; Stuut, Jan-Berend

    2015-04-01

    Large quantities of dust are transported from the Sahara Desert across the Atlantic Ocean towards the Caribbean each year, with a large portion of it deposited in the ocean. This dust brings an array of minerals, nutrients and organic matter, both living and dead. This input potentially fertilizes phytoplankton growth, with resulting knock-on effects throughout the food chain. The input of terrestrial microbial life may also have an impact on the marine microbial community. The current multi-year project consists of a transect of floating dust collectors and sub-surface sediment traps placed at 12°N across the Atlantic Ocean. Sediment traps are located 1200m and 3500m below the sea surface and all are synchronized to collect samples for a period of two weeks. The aim is to understand the links between dust input and the bacterial community and how this relates to ocean productivity and the carbon cycle. The first set of sediment trap samples were recovered using the RV Pelagia in November 2013 with promising results. Results from 7 sediment traps (three at 1200m and four at 3500m) were obtained. In general, the total mass flux decreased as distance from the source increased and the upper traps generally held more material than those at 3500m. Denaturing Gradient Gel Electrophoresis (DGGE) was used as a screening technique, revealing highly varied profiles, with the upper (1200m) traps generally showing more variation throughout the year. Several samples have been submitted for high throughput DNA sequencing which will identify the variations in these samples.

  19. Treatment of Visceral Aneurysm Using Multilayer Stent: Two-Year Follow-Up Results in Five Consecutive Patients

    SciTech Connect

    Balderi, Alberto Antonietti, Alberto Pedrazzini, Fulvio Sortino, Davide Vinay, Claudia Grosso, Maurizio

    2013-10-15

    Purpose: The present study was performed to analyze the midterm results (five consecutive patients, 2-year follow-up) of the endovascular management of visceral artery aneurysms using the Cardiatis Multilayer Flow Modulator (CMFM) (Cardiatis, Isnes, Belgium), a self-expandable stent. Materials and Methods: From August 2009 to January 2011, we implanted five CMFMs in five patients (all men; mean age 73 years) to treat two common hepatic artery aneurysms, one celiac trunk aneurysm, one splenic artery aneurysm, and one superior mesenteric artery aneurysm (diameter 25-81 mm). The primary end point was technical success. The secondary end point was stent patency, absence of aneurysm rupture or reperfusion, and shrinking of the sac at 6-, 12-, and 24-month follow-up using computed tomography angiography. Follow-up ranged from 24 to 48 months (mean 31.2). Results: Technical success was achieved in all patients. Complete exclusion of the aneurysm with sac shrinking was achieved in two patients. Two stents became occluded at 6- and 24-month follow-up, respectively; both patients were asymptomatic and were not retreated. One patient developed sac reperfusion due to incomplete aneurysm exclusion. Conclusion: Long-term results in a wider population are needed to validate the effectiveness of the CMFM.

  20. Offsite radiation doses from Hanford Operations for the years 1983 through 1987: A comparison of results calculated by two methods

    SciTech Connect

    Soldat, J.K.

    1989-10-01

    This report compares the results of the calculation of potential radiation doses to the public by two different environmental dosimetric systems for the years 1983 through 1987. Both systems project the environmental movement of radionuclides released with effluents from Hanford operations; their concentrations in air, water, and foods; the intake of radionuclides by ingestion and inhalation; and, finally, the potential radiation doses from radionuclides deposited in the body and from external sources. The first system, in use for the past decade at Hanford, calculates radiation doses in terms of 50-year cumulative dose equivalents to body organs and to the whole body, based on the methodology defined in ICRP Publication 2. This system uses a suite of three computer codes: PABLM, DACRIN, and KRONIC. In the new system, 50-year committed doses are calculated in accordance with the recommendations of the ICRP Publications 26 and 30, which were adopted by the US Department of Energy (DOE) in 1985. This new system calculates dose equivalent (DE) to individual organs and effective dose equivalent (EDE). The EDE is a risk-weighted DE that is designed to be an indicator of the potential health effects arising from the radiation dose. 16 refs., 1 fig., 38 tabs.

  1. Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma

    PubMed Central

    Gopal, Ajay K.; Smith, Scott E.; Ansell, Stephen M.; Rosenblatt, Joseph D.; Savage, Kerry J.; Connors, Joseph M.; Engert, Andreas; Larsen, Emily K.; Huebner, Dirk; Fong, Abraham; Younes, Anas

    2016-01-01

    Presented here are the 5-year end-of-study results from the pivotal phase 2 trial of brentuximab vedotin in patients with relapsed/refractory (R/R) Hodgkin lymphoma (HL) after failed hematopoietic autologous stem cell transplantation. At 5 years, the overall patient population (N = 102) had an estimated overall survival (OS) rate of 41% (95% confidence interval [CI]: 31-51) and progression-free survival (PFS) rate of 22% (95% CI: 13-31). Patients who achieved a complete response (CR) to brentuximab vedotin (N = 34) had estimated OS and PFS rates of 64% (95% CI: 48-80%) and 52% (95% CI: 34-69%), respectively. The median OS and PFS were not reached in CR patients, with 13 patients (38% of all CR patients) remaining in follow-up and in remission at study closure. Of the 13 patients, 4 received consolidative hematopoietic allogeneic stem cell transplant, and 9 (9% of all enrolled patients) remain in sustained CR without receiving any further anticancer therapy after treatment with brentuximab vedotin. Of the patients who experienced treatment-emergent peripheral neuropathy, 88% experienced either resolution (73%) or improvement (14%) in symptoms. These 5-year follow-up data demonstrate that a subset of patients with R/R HL who obtained CR with single-agent brentuximab vedotin achieved long-term disease control and may potentially be cured. The trial was registered at www.clinicaltrials.gov as #NCT00848926. PMID:27432875

  2. Head proportion and shape of the head of children between 2 and 7 years--results of a longitudinal study.

    PubMed

    Schüler, Grit

    2007-06-01

    Based upon a longitudinal anthropometric study with integrated picture documentation, the head proportion and head shape of two to seven years old children will be analysed. The study was initiated in April 2002 in the administrative districts of Potsdam and Potsdam-Mittelmark (Germany). 351 boys and girls have been measured and photographed. The children shall be examined up to four years until September 2006 with a half year investigation distance. Twenty-three anthropometric dimensions have been measured including six dimensions of the head. These dimensions of the head are the head length, head breadth, auricular height, interpupillary distance, facial height and lower face height. Furthermore, digital pictures have been taken of each child. So the head of each child can be examined in a frontal view (Norma frontalis) and in a lateral view (Norma lateralis) and will be analysed relating to changing proportions of the head. The results demonstrated and discussed here are based on a longitudinal succession of photos and point out a method to make individual patterns of the changing head proportions and head shape visual on pictures.

  3. Five-year results of a randomised controlled trial comparing mobile and fixed bearings in total knee replacement.

    PubMed

    Breeman, S; Campbell, M K; Dakin, H; Fiddian, N; Fitzpatrick, R; Grant, A; Gray, A; Johnston, L; MacLennan, G S; Morris, R W; Murray, D W

    2013-04-01

    There is conflicting evidence about the merits of mobile bearings in total knee replacement, partly because most randomised controlled trials (RCTs) have not been adequately powered. We report the results of a multicentre RCT of mobile versus fixed bearings. This was part of the knee arthroplasty trial (KAT), where 539 patients were randomly allocated to mobile or fixed bearings and analysed on an intention-to-treat basis. The primary outcome measure was the Oxford Knee Score (OKS) plus secondary measures including Short Form-12, EuroQol EQ-5D, costs, cost-effectiveness and need for further surgery. There was no significant difference between the groups pre-operatively: mean OKS was 17.18 (sd 7.60) in the mobile-bearing group and 16.49 (sd 7.40) in the fixed-bearing group. At five years mean OKS was 33.19 (sd 16.68) and 33.65 (sd 9.68), respectively. There was no significant difference between trial groups in OKS at five years (-1.12 (95% confidence interval -2.77 to 0.52) or any of the other outcome measures. Furthermore, there was no significant difference in the proportion of patients with knee-related re-operations or in total costs. In this appropriately powered RCT, over the first five years after total knee replacement functional outcomes, re-operation rates and healthcare costs appear to be the same irrespective of whether a mobile or fixed bearing is used.

  4. [Neurologic appearence of Behçet disease in 14-year old boy treated with adalimumab with good result].

    PubMed

    Iwańczak, Barbara; Reich, Adam; Kofla-Dłubacz, Anna; Kazanowska, Bernarda; Ruczka, Małgorzata

    2016-02-01

    Behçet disease is a multiorgan inflammatory vessel disorder of unknown etiology which only occasionally occurs in children. Here, we demonstrate a 14-year-old boy with Behçet disease diagnosed based on recurrent aphthous stomatitis, acneiform facial lesions, subpreputial erosions and extensive thrombosis involving sigmoid sinus, transverse sinus and right internal cervical vein. Treatment with low molecular weight heparins, systemic corticosteroids, and azathioprine only resulted in partial remission of clinical symptoms. Addition of adalimumab led to complete resolution of clinical and biochemical abnormalities and disappearance of thrombosis in central nervous system.

  5. The Hobby-Eberly Telescope Chemical Abundances of Stars in the Halo (CASH) Project. First Year Results

    NASA Astrophysics Data System (ADS)

    Frebel, Anna; Allende Prieto, C.; Davies, L. A.; Roederer, I.; Shetrone, M.; Sneden, C.; Rhee, J.; Beers, T. C.; Cowan, J. J.

    2007-12-01

    We introduce the The Hobby-Eberly Telescope Chemical Abundances of Stars in the Halo (CASH) Project. This University of Texas Long Term Project aims at discovering metal-poor Galactic halo stars selected from various surveys. We present the results of the first year of HET observations: Thus far, 200 objects are observed with the high-resolution spectrograph. Data reduction and stellar parameter determination, as well as our automated analysis procedure are described. A handful of stars with [Fe/H]<-3.0 were found. We also report an individual abundance analysis of three metal-poor program stars that confirm our automated analysis techniques.

  6. Immediate Nonfunctional Loading of Two Single-Maxillary Postextractive Implants: 6-Year Postloading Results of Two Case Reports.

    PubMed

    Ariano, Vincenzo; Mancini, Manuele; Cardi, Andrea; Condò, Roberta; Cerroni, Loredana; Pasquantonio, Guido

    2016-01-01

    Objectives. The aim of the study was to evaluate and compare crestal bone loss of single-maxillary immediate postextractive implants and immediate nonfunctional loading (INFL) during 72 months of follow-up. Material and Methods. Two single titanium implants (Certain Prevail, Biomet 3I, USA) were placed in two patients using INFL technique. Implant stability and crestal bone level were measured on periapical radiographs at 1, 3, and 6 months after surgery. Results. All osseointegrated implants were clinically successful after 6 years of functional loading. Conclusion. Within the limit of the present case report, the paper supports the concept that INFL of single dental implant can be a successful treatment procedure.

  7. Prone Accelerated Partial Breast Irradiation After Breast-Conserving Surgery: Five-year Results of 100 Patients

    SciTech Connect

    Formenti, Silvia C.; Hsu, Howard; Fenton-Kerimian, Maria; Roses, Daniel; Guth, Amber; Jozsef, Gabor; Goldberg, Judith D.; DeWyngaert, J. Keith

    2012-11-01

    Purpose: To report the 5-year results of a prospective trial of three-dimensional conformal external beam radiotherapy (3D-CRT) to deliver accelerated partial breast irradiation in the prone position. Methods and Materials: Postmenopausal patients with Stage I breast cancer with nonpalpable tumors <2 cm, negative margins and negative nodes, positive hormone receptors, and no extensive intraductal component were eligible. The trial was offered only after eligible patients had refused to undergo standard whole-breast radiotherapy. Patients were simulated and treated on a dedicated table for prone setup. 3D-CRT was delivered at a dose of 30 Gy in five 6-Gy/day fractions over 10 days with port film verification at each treatment. Rates of ipsilateral breast failure, ipsilateral nodal failure, contralateral breast failure, and distant failure were estimated using the cumulative incidence method. Rates of disease-free, overall, and cancer-specific survival were recorded. Results: One hundred patients were enrolled in this institutional review board-approved prospective trial, one with bilateral breast cancer. One patient withdrew consent after simulation, and another patient elected to interrupt radiotherapy after receiving two treatments. Ninety-eight patients were evaluable for toxicity, and, in 1 case, both breasts were treated with partial breast irradiation. Median patient age was 68 years (range, 53-88 years); in 55% of patients the tumor size was <1 cm. All patients had hormone receptor-positive cancers: 87% of patients underwent adjuvant antihormone therapy. At a median follow-up of 64 months (range, 2-125 months), there was one local recurrence (1% ipsilateral breast failure) and one contralateral breast cancer (1% contralateral breast failure). There were no deaths due to breast cancer by 5 years. Grade 3 late toxicities occurred in 2 patients (one breast edema, one transient breast pain). Cosmesis was rated good/excellent in 89% of patients with at least 36

  8. Replacement of Vertebral Lamina (Laminoplasty) in Surgery for Lumbar Isthmic Spondylolisthesis: 5-Year Follow-Up Results

    PubMed Central

    2016-01-01

    Study Design A review of clinical and radiological outcomes of lumbar laminoplasty (LL) for the treatment of isthmic spondylolisthesis (ISL). Purpose The single session performance of posterior lumbar interbody fusion with allograft in the anterior column and providing the realignment of the vertebrae was presented as a preliminary report earlier. Overview of Literature Long-term surgical outcome of cervical laminoplasty in patients has been reported. But, outcome of LL in patients is unclear. Methods The long-term (5 years) year follow-up results of the LL technique are reported in this retrospective study. All patients underwent preoperative and postoperative direct X-ray, computed tomography, and magnetic resonance imaging. The patients that did not respond to conservative treatment were operated. Twenty-one (52.5%) female and 19 (47.5%) male patients were included. Results Mean age was 43,5 years (ranges, 22–57 years). The most common symptoms were low back pain (89%), pelvic and leg pain (69%) and reduction in walking distance (65%). A total of 180 pedicle screws were inserted in 40 patients; posterior lumbar interbody fusion and laminoplasty with reduction was performed in 20 patients for L4–L5, 12 patients for L5–S1, 4 patients for L3–L4–L5 and 4 patients for L4–L5-S1. Ten (25%) patients with ILL had accompanying spinal stenosis. The difference between preoperative and postoperative sagittal plane rotation and dislocation degrees and disc space heights were statistically significant in all patients (p<0.05). Solid grade 4 fusion was observed in 38 patients; in only 2 patients grade 2 pseudoarthrosis developed (5%), but these patients were asymptomatic. Visual analog scale, Prolo economical and functional scale was examined with an average follow-up 5.5 years. Conclusions LL technique has the advantages of shorter duration of operation, lack of graft donor site complications, protection of posterior column osseoligamentous structures and

  9. Implementing the Common Core State Standards: Year Three Progress Report from the Great City Schools. Results from 2013-14 School Year

    ERIC Educational Resources Information Center

    Palacios, Moses; Casserly, Michael; Corcoran, Amanda; Hart, Ray; Simon, Candace; Uzzell, Renata

    2014-01-01

    Three years ago, the "Council of the Great City Schools" embarked on a multi-year initiative to help its member school districts implement the Common Core State Standards (CCSS). Part of this initiative involves annual surveys of progress urban public school districts were making in implementing the CCSS. With the support of the Bill…

  10. Number of Physics Faculty in Two-Year Colleges: Results from the 2012 Survey of Physics in Two-Year Colleges. Focus On

    ERIC Educational Resources Information Center

    White, Susan; Chu, Raymond

    2013-01-01

    In an earlier report, ("Physics Enrollments in Two-Year Colleges," ED547610), Susan White and Raymond Chu examined physics enrollments--both the number of students and the types of classes taught--at the 1,063 two-year college campuses in the US where they believe physics is offered. This "Focus On" considers the faculty…

  11. Vitamin D Status, Insulin Resistance, Leptin-To-Adiponectin Ratio in Adolescents: Results of a 1-Year Lifestyle Intervention

    PubMed Central

    Rambhojan, Christine; Larifla, Laurent; Clepier, Josiane; Bouaziz-Amar, Elodie; Velayoudom-Cephise, Fritz-Line; Blanchet-Deverly, Anne; Armand, Christophe; Plumasseau, Jean; Lacorte, Jean-Marc; Foucan, Lydia

    2016-01-01

    AIM: We aimed to study the relationships between circulating 25-hydroxyvitamin D [25(OH)D], insulin resistance and leptin-to-adiponectin (L/A) ratio in Guadeloupean children and adolescents and to analyse the changes in 25(OH)D levels after a 1-year lifestyle intervention program. METHODS: 25(OH)D concentrations were measured via a chemiluminescence assay. Cardiometabolic risk factors, homoeostasis model assessment of insulin resistance (HOMA-IR), and adipokines were measured. The lifestyle intervention included dietary counselling, regular physical activity. RESULTS: Among 117 girls and boys (11–15 years old, 31.6% obese), 40% had vitamin D deficiency (25(OH)D levels < 20 ng/mL). With linear regression models where 25(OH)D and HOMA-IR acted as independent variables and age, sex, BMI, L/A ratio as covariates, 25(OH)D was significantly associated with HOMA-IR alone (P = 0.036). HOMA-IR was also associated with BMI z-score ≥ 2, L/A ratio and an interaction term BMI z-score ≥ 2*L/A ratio (P < 0.001 for all). After one year, in 78 children/adolescent, mean serum 25(OH)D increased significantly from 21.4 ± 4.9 ng/mL at baseline to 23.2 ± 6.0 after 1 year; P = 0.003 whereas BMI z-score, HOMA-IR and L/A ratio decreased significantly (P = 0.003, P < 0.001 and P = 0.012; respectively). CONCLUSION: The association between 25(OH)D and HOMA-IR, independently of obesity and the high prevalence of vitamin D deficiency should be considered in order to prevent the later incidence of T2DM. A healthy lifestyle including non-sedentary and outdoor activities could be a way for improving vitamin D status. PMID:28028397

  12. Risk factors for late-onset generalized anxiety disorder: results from a 12-year prospective cohort (the ESPRIT study).

    PubMed

    Zhang, X; Norton, J; Carrière, I; Ritchie, K; Chaudieu, I; Ancelin, M-L

    2015-03-31

    Generalized anxiety disorder (GAD) is a chronic and highly prevalent disorder associated with increased disability and mortality in the elderly. Treatment is difficult with low rate of full remission, thus highlighting the need to identify early predictors for prevention in elderly people. The aim of this study is to identify and characterize incident GAD predictors in elderly people. A total of 1711 individuals aged 65 years and above and free of GAD at baseline were randomly recruited from electoral rolls between 1999 and 2001 (the prospective ESPRIT study). The participants were examined at baseline and five times over 12 years. GAD and psychiatric comorbidity were diagnosed with a standardized psychiatric examination, the Mini-International Neuropsychiatry Interview on the basis of DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth edition) criteria and validated by a clinical panel. During the follow-up, 8.4% (95% confidence interval=7.1-9.7%) of the participants experienced incident GAD, 80% being first episodes; the incident rate being 10 per 1000 person-years. The principal predictors of late-onset incident GAD over 12 years derived from a multivariate Cox model were being female, recent adverse life events, having chronic physical (respiratory disorders, arrhythmia and heart failure, dyslipidemia, cognitive impairment) and mental (depression, phobia and past GAD) health disorders. Poverty, parental loss or separation and low affective support during childhood, as well as history of mental problems in parents were also significantly and independently associated with incident GAD. GAD appears as a multifactorial stress-related affective disorder resulting from both proximal and distal risk factors, some of them being potentially modifiable by health care intervention.

  13. Minimum 5-year Follow-up Results of Minimally Invasive Total Knee Arthroplasty Using Mini-Keel Modular Tibial Implant

    PubMed Central

    Yoo, Ju-Hyung; Park, Byoung-Kyu; Han, Chang-Dong; Oh, Hyun-Cheol

    2014-01-01

    Purpose To evaluate the minimum 5-year mid-term clinical and radiological results of minimally invasive surgery total knee arthroplasty (MIS-TKA) using a mini-keel modular tibia component. Materials and Methods We retrospectively evaluated 254 patients (361 cases) who underwent MIS-TKA between 2005 and 2006. The latest clinical and radiological assessments were done in 168 cases that had been followed on an outpatient basis for more than 5 postoperative years. Clinical results were assessed using the Hospital for Special Surgery (HSS) score and Knee Society score. Radiological evaluation included measurements of knee alignment. Results The average postoperative knee range of motion and HSS score were 134.3°±12.4° and 92.7°±7.0°, respectively. The average postoperative femorotibial angle and tibial component alignment angle were 5.2°±1.7° valgus and 90.2°±1.6°, respectively. The average tibial component posterior inclination was 4.8°±2.1°. The percentage of cases with tibial component alignment angle of 90°±3° was 96.1%, and that with the femorotibial angle of 6°±3° valgus was 94.0%. Radiolucent lines were observed in 20 cases (12.0%): around the femur, tibia, and patella in 14 cases, 10 cases, and 1 case, respectively. However, they were less than 2 mm and non-progressive in all cases. The survival rate was 99.4% and there was no implant-related revision. Conclusions MIS-TKA using a mini-keel modular tibial plate showed satisfactory results, a high survival rate, and excellent clinical and radiological results in the mid-term follow-up. PMID:25229044

  14. The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study

    PubMed Central

    Şıklar, Zeynep; Genens, Mikayir; Poyrazoğlu, Şükran; Baş, Firdevs; Darendeliler, Feyza; Bundak, Rüveyde; Aycan, Zehra; Savaş Erdeve, Şenay; Çetinkaya, Semra; Güven, Ayla; Abalı, Saygın; Atay, Zeynep; Turan, Serap; Kara, Cengiz; Can Yılmaz, Gülay; Akyürek, Nesibe; Abacı, Ayhan; Çelmeli, Gamze; Sarı, Erkan; Bolu, Semih; Korkmaz, Hüseyin Anıl; Şimşek, Enver; Çatlı, Gönül; Büyükinan, Muammer; Çayır, Atilla; Evliyaoğlu, Olcay; İşgüven, Pınar; Özgen, Tolga; Hatipoğlu, Nihal; Elhan, Atilla Halil; Berberoğlu, Merih

    2016-01-01

    Objective: Noonan syndrome (NS) is a multisystem disorder, and short stature is its most striking manifestation. Optimal growth hormone (GH) treatment for NS is still controversial. In this study, using a nationwide registration system, we aimed to evaluate the growth characteristics and the clinical features of NS patients in Turkey and their growth response to GH treatment. Methods: Children and adolescents with a diagnosis of NS were included inthe study. Laboratory assessment including standard GH stimulation test results were evaluated. Height increment of patients with or without GH treatment were analyzed after three years of therapy. Results: A total of 124 NS patients from different centers were entered in the web-based system. Short stature and typical face appearance were the most frequently encountered diagnostic features of our patients. Of the 84 patients who were followed long-term, 47 hadreceived recombinant human GH (rhGH). In this group of 47 patients, height standard deviation score (HSDS) increased from -3.62±1.14 to -2.85±0.96 after three years of therapy, indicating significant differences from the patients who did not receive GH treatment. PTPN11 gene was analyzed in 61 patients, and 64% of these patients were found to have a mutation. HSDS at admission was similar in patients with or without PTPN11 gene mutation. Conclusion: A diagnosis of NS should be kept in mind in all patients with short stature showing systemic clinical findings. GH therapy is effective for improvement of short stature especially in the first two years of treatment. Further studies are needed for optimisation of GH therapy and evaluation of final height data in NS patients. PMID:27125300

  15. Sustained efficacy of risedronate in men with primary and secondary osteoporosis: results of a 2-year study.

    PubMed

    Ringe, Johann D; Farahmand, Parvis; Faber, Herbert; Dorst, Alfred

    2009-01-01

    The aim of this study was to assess the effect of treatment with risedronate 5 mg daily relative to control in men with primary or secondary osteoporosis over 2 years. Osteoporosis is a common condition in men that can have serious clinical consequences. In an earlier interim report, we found that 1 year of risedronate therapy resulted in significant increases in bone mineral density (BMD) and a significant reduction in vertebral fractures compared to control in men with osteoporosis. We conducted an open-label, prospective, match-control trial on men with primary or secondary osteoporosis in a single center, outpatient setting. Men with primary or secondary osteoporosis, as defined by a baseline lumbar spine BMD T-score < or = -2.5 and a baseline femoral neck BMD T-score < or = 2.0, were eligible for this study. Patients who had been treated with bisphosphonates or fluoride within the last 12 months were excluded. A total of 316 men were randomized to risedronate (n = 158) or control (n = 158). Patients were stratified by the presence of prevalent vertebral fractures at baseline and case by case allocated to either daily treatment with risedronate 5 mg daily plus calcium (1,000 mg) and vitamin D (800 IU) or to a control group (daily alfacalcidol (1 microg) plus calcium (500 mg) for those with prevalent vertebral fractures; daily vitamin D (800 IU) plus calcium (1,200 mg) for those without previous vertebral fractures). Primary study end points were identified prior to study initiation as the incidence of new vertebral fractures and changes in BMD at the lumbar spine, femoral neck, and total hip. Other end points included incidence of nonvertebral fractures and change in body height and back pain. Compared to control, the incidence of new vertebral fractures was significantly reduced in the risedronate 5 mg daily group at 2 years [14/152 (9.2%) for risedronate vs. 35/148 (23.6%) for control (61% risk reduction; P = 0.0026)]. Treatment with risedronate 5 mg daily

  16. Possible Niches For Extant Life On Titan In Light Of The First Six Years Of Cassini/Huygens Results

    NASA Astrophysics Data System (ADS)

    Grinspoon, David H.; Schulze-Makuch, D.

    2010-10-01

    At the 2005 DPS meeting we presented an assessment of the possibility of extant life on Titan after the first year of the Cassini mission at Saturn. We suggested then that hydrogenation of photochemically produced acetylene could provide metabolic energy for near-surface organisms and also replenish atmospheric methane (Schulze-Makuch and Grinspoon, 2005). In this talk we will offer a brief reassessment of the possibility of extant life in light of five more years of the Cassini/Huygens results, including the recent reports suggesting a lack of acetylene on the surface (Clark et al., 2010) and a possible sink of H2 at the surface (Strobel, 2010). Both results are consistent with earlier predictions for the existence of an acetylene-powered biosphere on Titan (Schulze-Makuch and Grinspoon, 2005; McKay and Smith, 2005), but can potentially be explained by more prosaic phenomena. D. Schulze-Makuch and D. H. Grinspoon(2005), Biologically Enhanced Energy and Carbon Cycling on Titan? Astrobiology 5, 560-567; Clarke, R.N. et al. (2020), Detection and Mapping of Hydrocarbon Deposits on Titan, JGR-Planets; Strobel, D.F(2010) Molecular hydrogen in Titan's atmosphere: Implications of the measured tropospheric and thermospheric mole fractions. Icarus; McKay, C.P., Smith, H.D.( 2005) Possibilities for methanogenic life in liquid methane on the surface of Titan. Icarus 178, 274-276.

  17. Sustainable Permaculture systems demonstration in the high mountain desert region of New Mexico -- results of five years practice

    SciTech Connect

    Lawrence, V.

    1997-12-31

    This paper reports on five years of results in the Permaculture restoration of a mountain drylands ranch outside Santa Fe, New Mexico. Dramatic results have been produced in the areas of erosion control, pastureland restoration, wild species propagation, aquaculture, riparian zone (wetland) restoration, edible landscape design and installation methodologies. Recently completed work includes a grant-financed (US Fish and Wildlife Service Partners for Wildlife Program) replanting and redevelopment of the entire riparian zone of the ranch and the design and development of a trout-spawning pond system that is self contained and self-purifying, with circulation through a structured wetland provided by a photovoltaic pumping system. The paper presents the design philosophy, overall design strategy and significant details of specific strategies, projects, and systems.

  18. Quality-assurance results for routine water analyses in U.S. Geological Survey laboratories, water year 1998

    USGS Publications Warehouse

    Ludtke, Amy S.; Woodworth, Mark T.; Marsh, Philip S.

    2000-01-01

    The U.S. Geological Survey operates a quality-assurance program based on the analyses of reference samples for two laboratories: the National Water Quality Laboratory and the Quality of Water Service Unit. Reference samples that contain selected inorganic, nutrient, and low-level constituents are prepared and submitted to the laboratory as disguised routine samples. The program goal is to estimate precision and bias for as many analytical methods offered by the participating laboratories as possible. Blind reference samples typically are submitted at a rate of 2 to 5 percent of the annual environmental-sample load for each constituent. The samples are distributed to the laboratories throughout the year. The reference samples are subject to the identical laboratory handling, processing, and analytical procedures as those applied to environmental samples and, therefore, have been used as an independent source to verify bias and precision of laboratory analytical methods and ambient water-quality measurements. The results are stored permanently in the National Water Information System and the Blind Sample Project's data base. During water year 1998, 95 analytical procedures were evaluated at the National Water Quality Laboratory and 63 analytical procedures were evaluated at the Quality of Water Service Unit. An overall evaluation of the inorganic and low-level constituent data for water year 1998 indicated 77 of 78 analytical procedures at the National Water Quality Laboratory met the criteria for precision. Silver (dissolved, inductively coupled plasma-mass spectrometry) was determined to be imprecise. Five of 78 analytical procedures showed bias throughout the range of reference samples: chromium (dissolved, inductively coupled plasma-atomic emission spectrometry), dissolved solids (dissolved, gravimetric), lithium (dissolved, inductively coupled plasma-atomic emission spectrometry), silver (dissolved, inductively coupled plasma-mass spectrometry), and zinc

  19. The Canadian Arctic Atmospheric Chemistry Experiment (ACE) Validation Project: Overview and results from ten years of ACE operations

    NASA Astrophysics Data System (ADS)

    Walker, Kaley; Strong, Kimberly

    2014-05-01

    As of February 2014, the Canadian-led Atmospheric Chemistry Experiment (ACE) satellite mission has been making measurements of the Earth's atmosphere for ten years. As ACE operations have extended beyond the initial two-year mission, there is a continuing need to validate the trace gas data products from the ACE-Fourier Transform Spectrometer (ACE-FTS) and the Measurement of Aerosol Extinction in the Stratosphere and Troposphere Retrieved by Occultation (ACE-MAESTRO) instruments. Ground-based measurements provide critical data for the validation of satellite retrievals of trace gases and for the assessment of long-term stability of these measurements. In particular, validation comparisons are needed for ACE during Arctic springtime to understand better the measurements of species involved in stratospheric ozone chemistry. To this end, eleven Canadian Arctic Atmospheric Chemistry Experiment (ACE) Validation Campaigns have been conducted during the spring period (February - April in 2004 - 2014) at the Polar Environment Atmospheric Research Laboratory (PEARL) in Eureka, Nunavut (80°N, 86°W). This period coincides with the most chemically active time of year in the Arctic, as well as a significant number of satellite overpasses. A suite of as many as 12 ground-based instruments, as well as frequent balloon-borne ozonesonde and radiosonde launches, have been used in each campaign. These instruments include: a ground-based version of the ACE-FTS (PARIS - Portable Atmospheric Research Interferometric Spectrometer), a terrestrial version of the ACE-MAESTRO, a SunPhotoSpectrometer, two zenith-viewing UV-visible grating spectrometers, a Bomem DA8 Fourier transform spectrometer, a Bruker 125HR Fourier transform spectrometer, a Systeme d'Analyse par Observations Zenithales (SAOZ) instrument, and several Brewer spectrophotometers. In the past several years, these results have been used to validate the measurements by the ACE-FTS and ACE-MAESTRO instruments on SCISAT as well

  20. A survey of occupational cancer in the rubber and cablemaking industries: results of five-year analysis, 1967-71

    PubMed Central

    Fox, A. J.; Lindars, D. C.; Owen, R.

    1974-01-01

    Fox, A. J., Lindars, D. C., and Owen, R. (1974).British Journal of Industrial Medicine,31, 140-151. A survey of occupational cancer in the rubber and cablemaking industries: results of five-year analysis, 1967-71. A mortality study of 40 867 subjects employed in the rubber and cablemaking industries on 1 February 1967 is reported. No evidence is found of a continued excess risk of neoplasms of the bladder in people who entered the industry after 1949. For those employed before that date, during the period when known bladder carcinogens were in use, the SMR is higher than predicted, indicating that men are still dying with occupationally induced tumours. An excess of all neoplasms was noted in the five years of the study. In certain sections of the industry (tyre manufacture, belting hose rubber with asbestos, and flooring industry) there is a particular excess of bronchial carcinoma. In those sections which use asbestos such an excess is not altogether surprising, but this does not apply to the tyre industry. The latter industry is sufficiently large (16 035 men in the study compared with 4 350 in the belting, hose rubber with asbestos, and flooring industry) for attention to be focused on particular operations. Two job groups are found to share the excess: moulding, press, autoclave, and pan curemen; and finished goods, packaging, and despatch. Job selection may play a part in the latter, as the work is generally considered suitable for older and perhaps less healthy people. Crude analyses have been undertaken to indicate whether the excesses are due to regional differences or to the population comprising an abnormally high proportion of smokers. No excesses are found in other smoking-related diseases. Although the effects of differences in smoking habit and regional differences cannot be ruled out, the indications are against these factors being the primary cause. The difficulties of this type of study are discussed. It is emphasized that the results can be used

  1. Calcium supplementation and the risks of atherosclerotic vascular disease in older women: results of a 5-year RCT and a 4.5-year follow-up.

    PubMed

    Lewis, Joshua R; Calver, Janine; Zhu, Kun; Flicker, Leon; Prince, Richard L

    2011-01-01

    Concern has been expressed that calcium supplementation, a key intervention for preventing osteoporotic fracture in older women, may increase the risk of atherosclerotic vascular disease. To evaluate the risk further, an examination of complete verified atherosclerotic vascular hospitalization and mortality data from a 5-year randomized, controlled trial (RCT) of calcium carbonate and 4.5 years of posttrial follow-up was undertaken. This study used data from a published 5-year randomized, double-blinded, placebo-controlled trial [Calcium Intake Fracture Outcome Study (CAIFOS)]. The participants were 1460 women aged 75.1 ± 2.7 years at baseline (1998) recruited from the general population and randomized to receive 1200 mg of calcium carbonate daily or an identical placebo. All hospital admission and deaths during the 5-year study and the 4.5-year follow-up were derived from the Western Australian Data Linkage Service (WADLS). Hazard ratios (HRs) for the combined endpoint of atherosclerotic vascular mortality or first hospitalization were calculated using prespecified intention-to-treat and per-protocol models. The intervention group that received calcium supplementation did not have a higher risk of death or first-time hospitalization from atherosclerotic vascular disease in either the 5-year RCT [multivariate-adjusted HR = 0.938, 95% confidence interval (CI) 0.690-1.275] or during the 9.5 years of observational study (multivariate-adjusted HR = 0.919, 95% CI 0.737-1.146). Further analysis suggested that calcium supplementation may reduce the risk of hospitalization and mortality in patients with preexisting atherosclerotic cardiovascular disease. This trial provides compelling evidence that calcium supplementation of 1200 mg daily does not significantly increase the risk of atherosclerotic vascular disease in elderly women.

  2. Accelerated partial breast irradiation in the elderly: 5-year results of high-dose rate multi-catheter brachytherapy

    PubMed Central

    2014-01-01

    Objective To evaluate clinical outcome after accelerated partial breast irradiation (APBI) in the elderly after high-dose-rate interstitial multi-catheter brachytherapy (HIBT). Methods and materials Between 2005 and 2013, 70 patients underwent APBI using HIBT. Catheter implant was performed intra or post-operatively (referred patients) after lumpectomy and axillary sentinel lymph node dissection. Once the pathological results confirmed the indication of APBI, planification CT-scan was performed to deliver 34 Gy/10f/5d or 32 Gy/8f/4d. Dose-volume adaptation was manually achieved (graphical optimization). Dosimetric results and clinical outcome were retrospectively analyzed. Physician cosmetic evaluation was reported. Results With a median follow-up of 60.9 months [4.6 – 90.1], median age was 80.7 years [62 – 93.1]. Regarding APBI ASTRO criteria, 61.4%, 18.6% and 20% were classified as suitable, cautionary and non-suitable respectively. Axillary sentinel lymph node dissection was performed in 94.3%; 8 pts (11.5%) presented an axillary involvement. A median dose of 34 Gy [32 – 35] in 8 to 10 fractions was delivered. Median CTV was 75.2 cc [16.9 – 210], median D90 EQD2 was 43.3 Gy [35 – 72.6] and median DHI was 0.54 [0.19 – 0.74]. One patient experienced ipsilateral recurrence (5-year local free recurrence rate: 97.6%. Five-year specific and overall survival rates were 97.9% and 93.2% respectively. Thirty-four patients (48%) presented 47 late complications classified grade 1 (80.8%) and grade 2 (19.2%) with no grade ≥ 3. Cosmetic results were considered excellent/good for 67 pts (95.7%). Conclusion APBI using HIBT and respecting strict rules of implantation and planification, represents a smart alternative between no post-operative irradiation and whole breast irradiation delivered over 6 consecutive weeks. PMID:24886680

  3. Longitudinal relationships between anxiety, depression, and pain: results from a two-year cohort study of lower extremity trauma patients.

    PubMed

    Castillo, Renan C; Wegener, Stephen T; Heins, Sara E; Haythornthwaite, Jennifer A; Mackenzie, Ellen J; Bosse, Michael J

    2013-12-01

    Previous studies have shown that pain, depression, and anxiety are common after trauma. A longitudinal relationship between depression, anxiety, and chronic pain has been hypothesized. Severe lower extremity trauma patients (n = 545) were followed at 3, 6, 12, and 24 months after injury using a visual analog "present pain intensity" scale and the depression and anxiety scales of the Brief Symptom Inventory. Structural model results are presented as Standardized Regression Weights (SRW). Multiple imputation was used to account for missing data. A single structural model including all longitudinal pain intensity, anxiety symptoms, and depression symptoms time-points yielded excellent fit measures. Pain weakly predicted depression (3-6 months SRW = 0.07, P = .05; 6-12 months SRW = 0.06, P = .10) and anxiety (3-6 months SRW = 0.05, P = .21; 6-12 months SRW = 0.08, P = .03) during the first year after injury, and did not predict either construct beyond 1 year. Depression did not predict pain over any time period. In contrast, anxiety predicted pain over all time periods (3-6 months SRW = 0.11, P = .012; 6-12 months SRW = 0.14, P = .0065; 12-24 months SRW = 0.18, P < .0001). The results suggest that in the early phase after trauma, pain predicts anxiety and depression, but the magnitude of these relationships are smaller than the longitudinal relationship from anxiety to pain over this period. In the late (or chronic) phase after injury, the longitudinal relationship from anxiety on pain nearly doubles and is the only significant relationship. Despite missing data and a single item measure of pain intensity, these results provide evidence that negative mood, specifically anxiety, has an important role in the persistence of acute pain.

  4. Nitinol stent implantation for femoropopliteal disease in patients on hemodialysis: results of the 3-year retrospective multicenter APOLLON study.

    PubMed

    Fujihara, Masahiko; Higashimori, Akihiro; Kato, Yoshihiro; Taniguchi, Hiromasa; Iwasaki, Yusuke; Amano, Tomonori; Sumiyoshi, Akinori; Nishiya, Daisuke; Yokoi, Yoshiaki

    2016-09-01

    The clinical outcomes of nitinol stents for femoropopliteal arterial (FP) disease in patients on hemodialysis were assessed. Endovascular therapy (EVT) is accepted for symptomatic FP disease. However, the clinical outcomes of patients on dialysis are not well known. A multicenter retrospective study was conducted with data between November 2010 and August 2013. A total of 484 consecutive patients who successfully underwent EVT for FP disease with nitinol stents were recruited and analyzed. Patients were categorized into the hemodialysis group (N = 161) and non-hemodialysis group (N = 323). The primary measure was primary patency verified by duplex ultrasound at a rest peak systolic velocity (PSVR) of >2.5, and secondary measures were freedom from target lesion revascularization (TLR) and major amputation-free survival (AFS). Average follow-up duration was 19.5 ± 13.5 months. The primary patency rate at 3 years was significantly lower in the hemodialysis group than the non-hemodialysis group (33.8 vs. 43.7 %; p = 0.036). Freedom from TLR at 3 years was 55.0 % in the hemodialysis group and 66.1 % in the non-hemodialysis group (p = 0.032). The hemodialysis group showed a significantly lower AFS rate at 3 years than the non-hemodialysis group (86.4 vs. 58.2 %; p < 0.001). In hemodialysis patients, nitinol stent use resulted in a lower patency rate, higher TLR rate, and lower AFS rate compared to non-hemodialysis patients. These data suggest that nitinol stent implantation for FP arteries in hemodialysis patient needs to be reconsidered.

  5. High-Dose-Rate Rotte 'Y' Applicator Brachytherapy for Definitive Treatment of Medically Inoperable Endometrial Cancer: 10-Year Results

    SciTech Connect

    Coon, Devin; Beriwal, Sushil Heron, Dwight E.; Kelley, Joseph L.; Edwards, Robert P.; Sukumvanich, Paniti; Zorn, Kristin K.; Krivak, Thomas C.

    2008-07-01

    Purpose: To assess the intermediate clinical outcomes of medically inoperable patients with endometrial cancer treated with definitive Rotte 'Y' applicator high-dose-rate brachytherapy (HDRB) over a 10-year period. Methods and Materials: Forty-nine inoperable patients were treated with HDRB from 1997 to 2007. Forty three (84%) were markedly obese (body mass index >35 kg/m{sup 2}). Thirty-one patients (63.3%) underwent two-dimensional treatment planning, whereas 18 patients (36.7%) underwent three-dimensional treatment planning. Thirty five of the patients (71.4%) were first treated with external beam radiotherapy (EBRT). For patients receiving EBRT in addition to HDRB, the median Y-applicator dose was 20 Gy in 5 fractions; for patients receiving HDRB alone it was 35 Gy in 5 fractions. All patients received two Y-applicator treatments per day. Results: Median follow-up time for all patients was 33 months. Acute HDRB toxicities were limited to Grade 1 and 2 occurring in 5 patients. One patient had a myocardial infarction. Four patients had late Grade 2 or 3 toxicity. Three patients had local recurrence (median time to recurrence, 16 months). The 3- and 5-year actuarial cause-specific survival rates were 93% and 87%, respectively; the overall survival rate was 83% and 42%, respectively, at 3 and 5 years. Conclusions: Twice-daily HDRB using a Y-applicator is a well-tolerated and efficacious regimen for the definitive treatment of medically inoperable patients with early-stage endometrial cancer. The recent incorporation of three-dimensional treatment planning has the potential to further decrease treatment morbidities.

  6. Diet in 1-year-old farm and control children and allergy development: results from the FARMFLORA birth cohort

    PubMed Central

    Jonsson, Karin; Green, My; Barman, Malin; Sjöberg, Agneta; Brekke, Hilde K.; Wold, Agnes E.; Sandberg, Ann-Sofie

    2016-01-01

    Background A farming environment confers strong protection against allergy development. We have previously shown that farming mothers consume more full-fat dairy than control mothers, who instead consume more low-fat dairy, margarine, and oils; margarine and oil intake was associated with increased risk of allergy development in their children. Objectives The aims of this study were to investigate the differences in diet between children in farming and control families at 1 year of age, to investigate the relation between the diets of the mothers and their children, and to relate the children's diet to allergy development. Design The diet of 1-year-old children from dairy farming families (n=28) and from control families in the same rural area (n=37) was assessed by 24-h dietary recalls, followed by 24-h food diaries. Allergy was diagnosed by pediatricians at 3 years of age using strict predefined criteria. Results Farm children had a higher intake of farm milk, whole cream, cholesterol, saturated fat, and fat in total and tended to eat more butter, while controls consumed more carbohydrates and poultry and tended to eat more margarine. Farm children also had higher intakes of homemade porridge/gruel, oily fish, and iodine. The intake of butter and whole milk in children and mothers correlated significantly in farm families but not in controls. A weak negative association was found between seafood intake and allergy development, while allergy was positively associated with the intake of pork as well as zinc in the control group; these intakes also correlated with each other. Conclusions Consistent with mothers in farming families, the children consumed more full-fat dairy and saturated fat than did controls, but this could not be linked to the low risk of allergy in the farming group. Seafood intake might protect against allergy development, in accordance with earlier findings. PMID:27534847

  7. Assessment of Ten-Year-Long Results of Kidney Biopsies Performed on Children in the Thrace Region of Turkey

    PubMed Central

    Özkayın, Neşe; Çıplak, Gökçe; Usta, Ufuk; Gençhellaç, Hakan; Temizöz, Osman

    2016-01-01

    Background Many children with kidney diseases can be diagnosed and treated without a biopsy. However, biopsy is a valuable method for the diagnostic and prognostic evaluation of children with kidney diseases. Aims To evaluate the clinical and pathological profiles of the kidney biopsies in our department to provide epidemiological data for clinical practice. Study Design Retrospective cross-sectional study. Methods Kidney biopsies and patient’s charts in pediatric patients performed between May 2005 and February 2015 at the Pediatric Nephrology Department, Trakya University School of Medicine were assessed retrospectively. Results A total of 100 patients were examined. Their mean age was 9.62±4.26 years (range: 1–17 years); 54% of the patients were girls and 46% were boys. The most frequent indication for kidney biopsy was nephrotic syndrome (33%). The most common kidney disease was primary glomerulonephritis, which was observed in 65% of cases. IgA nephropathy (24%) was the most frequently observed subtype in primary glomerulonephritis groups. Secondary glomerulonephritis was diagnosed in 35% of cases. Systemic lupus erythematosus (51%) was the most frequently observed subtype in the secondary glomerulonephritis groups. Conclusion IgA nephropathy and systemic lupus erythematosus were the most frequent primary and secondary glomerulonephritis in our region among children, respectively. PMID:27994909

  8. Multi-Year Analysis of Renewable Energy Impacts in California: Results from the Renewable Portfolio Standards Integration Cost Analysis; Preprint

    SciTech Connect

    Milligan, M.; Shiu, H.; Kirby, B.; Jackson, K.

    2006-08-01

    California's Renewable Portfolio Standard (RPS, Senate Bill 1078) requires the state's investor-owned utilities to obtain 20% of their energy mix from renewable generation sources. To facilitate the imminent increase in the penetration of renewables, the California Energy Commission (CEC), in support of the California Public Utility Commission (CPUC), initiated a study of integration costs in the context of RPS implementation. This effort estimated the impact of renewable generation in the regulation and load-following time scales and calculated the capacity value of renewable energy sources using a reliability model. The analysis team, consisting of researchers from the National Renewable Energy Laboratory (NREL), Oak Ridge National Laboratory (ORNL) and the California Wind Energy Collaborative (CWEC), performed the study in cooperation with the California Independent System Operator (CaISO), the Pacific Gas and Electric Company (PG&E), and Southern California Edison (SCE). The study was conducted over three phases and was followed by an analysis of a multi-year period. This paper presents results from the multi-year analysis and the Phase III recommendations.

  9. A screening programme for the prospective prevention of Mediterranean anaemia in Latium: results of seven years' work.

    PubMed

    Bianco, I; Graziani, B; Lerone, M; Congedo, P; Ponzini, D; Braconi, F; Aliquo, C

    1984-08-01

    Since 1975 the Rome Microcythaemia Centre has carried out every year, under the auspices of the health authorities of the Latium region, a screening of thalassaemics among intermediate schoolchildren of Latium. From these campaigns, knowledge about thalassaemias among the young adult population has grown which, in its turn, has resulted in screening of these young adults. Through screening in schools between 1975 and 1982, of 289 763 students examined, 6838 thalassaemics were identified, 6045 of whom were beta- or delta beta-thalassaemics. The total number of young thalassaemics who are identified at present in the Centre through screenings of schoolchildren and young adults is about 3300 per year. Furthermore, from January 1980 to April 1983, 110 prospective couples of child-bearing age at risk (94 of whom originated from Latium) were identified at the Centre, and five homozygous fetuses (three of which originated from Latium) were diagnosed. These data derive from an area in which the frequency of thalassaemia is only 2.4%, and they show that the programme in Latium for the prevention of Mediterranean anaemia has been successful.

  10. Immediate Nonfunctional Loading of Two Single-Maxillary Postextractive Implants: 6-Year Postloading Results of Two Case Reports

    PubMed Central

    Ariano, Vincenzo; Mancini, Manuele; Cardi, Andrea; Condò, Roberta; Cerroni, Loredana; Pasquantonio, Guido

    2016-01-01

    Objectives. The aim of the study was to evaluate and compare crestal bone loss of single-maxillary immediate postextractive implants and immediate nonfunctional loading (INFL) during 72 months of follow-up. Material and Methods. Two single titanium implants (Certain Prevail, Biomet 3I, USA) were placed in two patients using INFL technique. Implant stability and crestal bone level were measured on periapical radiographs at 1, 3, and 6 months after surgery. Results. All osseointegrated implants were clinically successful after 6 years of functional loading. Conclusion. Within the limit of the present case report, the paper supports the concept that INFL of single dental implant can be a successful treatment procedure. PMID:27293915

  11. [Experiences and results in hypertension screening in women between 20 and 65 years of age in Karl-Marx-City].

    PubMed

    Voigt, G; Börker, G; Edelmann, S; Hartung, A; Hartung, G; Heyne, S; Töpfer, V

    1980-11-15

    From 1975 to 1979 in the district of the City of Karl-Marx-Stadt 91,130 females at the age between 20 and 65 years were summoned to a gynaecologico-cardiological mass examination which was supported by computer. 56,460 females underwent the examination. According to the WHO-criteria two measurements of blood pressure were carried out, when increased blood pressure was present a third one and a fourth one by an examination group. A diagnostic standard programme was used. In the second measurement of blood pressure we established 19.8% of patients with hypertension and 28.6% patients with borderline values. 52.8% of the hypertensions were known. Of 10,685 females with known or established hypertension 10.1% underwent an optimum therapy. On the basis of these results a programme for the fight against hypertension was developed for the county Karl-Marx-Stadt.

  12. Results of calendar year 1994 monitor well inspection and maintenance program, Y-12 Plant, Oak Ridge, Tennessee

    SciTech Connect

    McMaster, B.W.; Jones, S.B.; Sitzler, J.L.

    1995-06-01

    This document is a compendium of results of the calendar year 1994 Monitor Well Inspection and Maintenance Program at the Department of Energy Y-12 Plant in Oak Ridge, Tennessee. This report documents the work relating to well inspections and maintenance requests. Inspections are implemented in order to better assess the condition and maintenance needs of wells that are actively being monitored. Currently this approach calls for inspecting all wells on a routine (annual or triennial) basis which are: (1) in an active sampling program; (2) included in a hydrologic study; or (3) not in service, but not scheduled for plugging and abandonment. Routine inspections help to ensure that representative groundwater samples and hydrologic data are being collected, and contribute to the life expectancy of each well. This report formally presents well inspection and maintenance activities that were conducted at the Y-12 Plant during 1994. All inspections were conducted between April and December.

  13. Results from a sixteen year study on the effects of oiling from the Exxon Valdez on adult pink salmon returns.

    PubMed

    Brannon, Ernest L; Maki, Alan W; Moulton, Lawrence L; Parker, Keith R

    2006-08-01

    For sixteen years following the 1989 Exxon Valdez oil spill adult returns of pink salmon in Prince William Sound, Alaska were monitored to assess spill effects on survival. No evidence of spill effects was detected for either intertidal or whole-stream spawning fish. From 1989 through 2004 mean densities for oiled and reference streams tracked each other, illustrating similar responses of oiled and reference stream adult populations to naturally changing oceanographic and climactic conditions. Hatchery fish strayed into the study streams, but similar incursions occurred in oiled and reference streams, and their presence was compensated for to eliminate their influence on determining the success of the returning natural populations. These results, showing no detectable effects of oiling on pink salmon spawning populations, are supported by published field studies on pink salmon incubation success in oiled streams.

  14. Neonatal screening for sickle cell diseases in Camberwell: results and recommendations of a two year pilot study.

    PubMed Central

    Horn, M E; Dick, M C; Frost, B; Davis, L R; Bellingham, A J; Stroud, C E; Studd, J W

    1986-01-01

    The sickle cell diseases are a major health problem for Afro-Caribbean peoples. Neonatal detection and prophylactic management can reduce mortality and morbidity in childhood. A study was therefore conducted analysing the results of the first two years of cord blood screening in the Camberwell health area. Thirteen cases of sickle cell disease and two of haemoglobin (Hb)C disease were identified among 2202 non-white infants screened. The carrier state, sickle cell trait (HbAS), was present in 11.9% and HbC trait (HbAC) in 4.1% of Afro-Caribbean infants. The incidence of disease and of carrier states was much higher in West Africans than in Caribbeans. The wider implications of screening and the need for a comprehensive plan of care are emphasised. PMID:3082419

  15. Worldwide Evaluations of Quinoa: Preliminary Results from Post International Year of Quinoa FAO Projects in Nine Countries.

    PubMed

    Bazile, Didier; Pulvento, Cataldo; Verniau, Alexis; Al-Nusairi, Mohammad S; Ba, Djibi; Breidy, Joelle; Hassan, Layth; Mohammed, Maarouf I; Mambetov, Omurbek; Otambekova, Munira; Sepahvand, Niaz Ali; Shams, Amr; Souici, Djamel; Miri, Khaled; Padulosi, Stefano

    2016-01-01

    Chenopodium quinoa Willd., a high quality grain crop, is resistant to abiotic stresses (drought, cold, and salt) and offers an optimal source of protein. Quinoa represents a symbol of crop genetic diversity across the Andean region. In recent years, this crop has undergone a major expansion outside its countries of origin. The activities carried out within the framework of the International Year of Quinoa provided a great contribution to raise awareness on the multiple benefits of quinoa as well as to its wider cultivation at the global level. FAO is actively involved in promoting and evaluating the cultivation of quinoa in 26 countries outside the Andean region with the aim to strengthen food and nutrition security. The main goal of this research is to evaluate the adaptability of selected quinoa genotypes under different environments outside the Andean region. This paper presents the preliminary results from nine countries. Field evaluations were conducted during 2013/2014 and 2014/2015 in Asia (Kyrgyzstan and Tajikistan), and the Near East and North African countries (Algeria, Egypt, Iraq, Iran, Lebanon, Mauritania, and Yemen). In each country, the trials were carried out in different locations that globally represent the diversity of 19 agrarian systems under different agro-ecological conditions. Twenty-one genotypes of quinoa were tested using the same experimental protocol in all locations consisting in a randomized complete block design (RCBD) with three replicates. Some genotypes showed higher yields and the Q18 and Q12 landraces displayed greater adaptation than others to new environmental conditions. The Q21 and Q26 landraces were evaluated with stable and satisfactory levels of yield (>1 t.ha(-1)) in each of the different trial sites. This production stability is of considerable importance especially under climate change uncertainty. While these results suggest that this Andean crop is able to grow in many different environments, social, and cultural

  16. Worldwide Evaluations of Quinoa: Preliminary Results from Post International Year of Quinoa FAO Projects in Nine Countries

    PubMed Central

    Bazile, Didier; Pulvento, Cataldo; Verniau, Alexis; Al-Nusairi, Mohammad S.; Ba, Djibi; Breidy, Joelle; Hassan, Layth; Mohammed, Maarouf I.; Mambetov, Omurbek; Otambekova, Munira; Sepahvand, Niaz Ali; Shams, Amr; Souici, Djamel; Miri, Khaled; Padulosi, Stefano

    2016-01-01

    Chenopodium quinoa Willd., a high quality grain crop, is resistant to abiotic stresses (drought, cold, and salt) and offers an optimal source of protein. Quinoa represents a symbol of crop genetic diversity across the Andean region. In recent years, this crop has undergone a major expansion outside its countries of origin. The activities carried out within the framework of the International Year of Quinoa provided a great contribution to raise awareness on the multiple benefits of quinoa as well as to its wider cultivation at the global level. FAO is actively involved in promoting and evaluating the cultivation of quinoa in 26 countries outside the Andean region with the aim to strengthen food and nutrition security. The main goal of this research is to evaluate the adaptability of selected quinoa genotypes under different environments outside the Andean region. This paper presents the preliminary results from nine countries. Field evaluations were conducted during 2013/2014 and 2014/2015 in Asia (Kyrgyzstan and Tajikistan), and the Near East and North African countries (Algeria, Egypt, Iraq, Iran, Lebanon, Mauritania, and Yemen). In each country, the trials were carried out in different locations that globally represent the diversity of 19 agrarian systems under different agro-ecological conditions. Twenty-one genotypes of quinoa were tested using the same experimental protocol in all locations consisting in a randomized complete block design (RCBD) with three replicates. Some genotypes showed higher yields and the Q18 and Q12 landraces displayed greater adaptation than others to new environmental conditions. The Q21 and Q26 landraces were evaluated with stable and satisfactory levels of yield (>1 t.ha−1) in each of the different trial sites. This production stability is of considerable importance especially under climate change uncertainty. While these results suggest that this Andean crop is able to grow in many different environments, social, and cultural

  17. Elaboration of the Environmental Stress Hypothesis–Results from a Population-Based 6-Year Follow-Up

    PubMed Central

    Wagner, Matthias; Jekauc, Darko; Worth, Annette; Woll, Alexander

    2016-01-01

    The aim of this paper was to contribute to the elaboration of the Environmental Stress Hypothesis framework by testing eight hypotheses addressing the direct impact of gross motor coordination problems in elementary-school on selected physical, behavioral and psychosocial outcomes in adolescence. Results are based on a longitudinal sample of 940 participants who were (i) recruited as part of a population-based representative survey on health, physical fitness and physical activity in childhood and adolescence, (ii) assessed twice within 6 years, between the ages of 6 and 10 years old as well as between the ages of 12 and 16 years old (Response Rate: 55.9%) and (iii) classified as having gross motor coordination problems (N = 115) or having no gross motor coordination problems (N = 825) at baseline. Motor tests from the Körperkoordinationstest, measures of weight and height, a validated physical activity questionnaire as well as the Strength and Difficulties Questionnaire were conducted. Data were analyzed by use of binary logistic regressions. Results indicated that elementary-school children with gross motor coordination problems show a higher risk of persistent gross motor coordination problems (OR = 7.99, p < 0.001), avoiding organized physical activities (OR = 1.53, p < 0.05), an elevated body mass (OR = 1.78, p < 0.05), bonding with sedentary peers (OR = 1.84, p < 0.01) as well as emotional (OR = 1.73, p < 0.05) and conduct (OR = 1.79, p < 0.05) problems in adolescence in comparison to elementary-school children without gross motor coordination problems. However, elementary-school children with gross motor coordination problems did not show a significantly higher risk of peer problems (OR = 1.35, p = 0.164) or diminished prosocial behavior (OR = 1.90, p = 0.168) in adolescence, respectively in comparison to elementary-school children without gross motor coordination problems. This study is the first to provide population-based longitudinal data ranging from

  18. OWN Survey: results after seven years of high-resolution spectroscopic monitoring of Southern O and WN stars

    NASA Astrophysics Data System (ADS)

    Barbá, R.; Gamen, R.; Arias, J. I.; Morrell, N.; Walborn, N. R.; Maíz Apellániz, J.; Sota, A.; Alfaro, E.

    2014-10-01

    We describe briefly the main results of the high-resolution spectroscopic monitoring survey of southern Galactic O- and WN-type stars. The high-resolution spectroscopic monitoring survey of O and WN stars (OWN Survey, Barbá et al. 2010) has completed seven years of sustained campaign, using observational facilities in Chile and Argentina. The selected sample corresponds to those stars for which there is no indication of multiplicity in the Galactic O-star Catalog (Maíz Apellániz et al. 2004) and the VII Catalogue of Galactic WR stars (van der Hucht 2001). We have collected almost 5000 spectra of about 240 O and WN stars. From that sample of 190 O-type stars, we have discovered 146 stars showing radial variations greater than 10 km/s, including 108 new systems, being 56 single-lined spectroscopic binaries, 43 double-lined spectroscopic binaries, and 9 multiple-lined binaries. The new orbital periods spanning from 1.5 to 2200 days. In this work, we present the main result of ``OWN Survey'': the determination of orbits for over fifty O-type spectroscopic binary systems, and the analysis of the spectral-type, luminosty, period, eccentricity, and mass-ratio distributions. This result is unprecedented in the context of massive binary stars, since we are almost doubling the number of Galactic O-type star systems with known orbits.

  19. [Pollen content of the Paris air: comparison of the results obtained by two samplers for the year 2003].

    PubMed

    Distigny, C; Polenne, J P; Bordenave, L; Bex, V; Squinazi, F

    2004-09-01

    During the 2003 season, a second pollen collector has been established in Paris city (Audubon site) to study the representativeness of the initial collector situated on the roof of the Pasteur Institute. The Hygiene Laboratory of Paris followed the pollen counts from the two collectors, during the period going from May to September. Both the samplers are Lanzoni model with a flow rate of 10 l x min(-1). The quantitative results show that no statistical difference exists between the pollen counts obtained from the 2 sites (Mann-Withney test, p > .05). The dominant species are Urticaceae, Poacae and Castenea species for the 2 collectors. Their counts are similar except for Poacae whose results are higher at the Audubon site. The collection period do not take into account the pollen production period of many trees species because of the late installation of the collector on the Audubon site. The results show that the two sites chosen for the study of pollen distribution are comparable. Nevertheless, the comparative study should be maintained on the next year to get more details about the observed differences and to collect the early trees pollen.

  20. Programs and Practices that Retain Students from the First to Second Year: Results from a National Study

    ERIC Educational Resources Information Center

    DeAngelo, Linda

    2014-01-01

    In this chapter findings from a nationally representative longitudinal study offer insights into how the experiences students have during their first college year affect their intention to be retained at their initial college for the second year.

  1. Physics Enrollments in Two-Year Colleges: Results from the 2012 Survey of Physics in Two-Year Colleges. Focus On

    ERIC Educational Resources Information Center

    White, Susan; Chu, Raymond

    2013-01-01

    This "Focus On" first considers the role two-year colleges (TYCs) play in post-secondary physics education. In their 2007 Survey of Undergraduate Seniors in degree-granting physics departments, the authors asked students if they had begun their post-secondary education at a TYC. Nine percent of the physics undergraduate seniors in 2007…

  2. 2011 Year-End Poll of Employers: A Look at Hiring and Salary Projections for the Coming Year. Summary of Results

    ERIC Educational Resources Information Center

    Estrada, Rebecca

    2011-01-01

    Not only do more companies plan to hire in 2012, they plan to hire at similar or increased levels compared to 2011, according to responses to the 2011 Year-End Poll of Employers of the Graduate Management Admission Council (GMAC). The annual poll of employers, which the Council conducted from November 2 to November 16, 2011, garnered responses…

  3. Large and Small Scale Nitrogen and Phosporous Manipulation Experiment in a Tree-Grass Ecosystem: first year of results

    NASA Astrophysics Data System (ADS)

    Migliavacca, Mirco; Perez Priego, Oscar; El-Madany, Tarek; Guan, JinHong; Carrara, Arnaud; Fava, Francesco; Moreno, Gerardo; Kolle, Olaf; Rossini, Micol; Schrumpf, Marion; Julitta, Tommaso; Reichstein, Markus

    2015-04-01

    Recent studies have shown how human induced N/P imbalances affect essential ecosystem processes (e.g. photosynthesis, plant growth rate, respiration), and might be particularly important in water-limited ecosystems. In this contribution we will present the experimental design and the results of the first year of two nutrient manipulation experiments conducted at different spatial scale. In the first experiment a cluster of 2 eddy covariance (EC) flux towers has been set up beside a long-term EC site (Las Majadas del Tietar, Spain). Sites are selected in a way to have similar nutrient conditions, canopy structure, and stoichiometry of the different vegetation and soil pools. Two of the three footprints will be manipulated with addition of N and NP fertilizer at the beginning of 2015. The comparison of the three EC flux towers installed during the first year of the experiment (without fertilization) will be shown. We characterized the differences of the responses of carbon and water fluxes measured by the EC systems to environmental drivers, and structural and biophysical properties of the canopy. The second experiment was conducted over a Mediterranean grassland, where 16 plots of 10x10 meters that were manipulated by adding nutrient (N, P, and NP). The overall objective was to investigate the response of the gross primary productivity (GPP), assessed by using transparent transient-state canopy chambers, to different nutrient availability. The second objective was to evaluate the capability of hyperspectral data and Solar induced fluorescence to track short- and long-term GPP and light use efficiency variation under different N and P fertilization treatments. Spectral vegetation indices (VIs) were acquired manually using high resolution spectrometers (HR4000, OceanOptics, USA) along a phenological cycle. The VIs used included photochemical reflectance index (PRI), MERIS terrestrial-chlorophyll index (MTCI) and normalized difference vegetation index (NDVI). Solar

  4. Adverse Drug Reactions in Hospitalised Children in Germany Are Decreasing: Results of a Nine Year Cohort-Based Comparison

    PubMed Central

    Oehme, Ann-Kathrin; Rashed, Asia N.; Hefele, Barbara; Wong, Ian C. K.; Rascher, Wolfgang; Neubert, Antje

    2012-01-01

    Background In recent years, efforts have been made to improve paediatric drug therapy. The aim of this research was to investigate any changes regarding the frequency and nature of adverse drug reactions (ADRs) in hospitalized children in one paediatric general medical ward over a 9-year period. Methodology Two prospective observational cohort studies were conducted at a large University hospital in Germany in 1999 and 2008, respectively. Children aged 0–18 years admitted to the study ward during the study periods were included. ADRs were identified using intensive chart review. Uni- and multivariable regression has been used for data analysis. Results A total of 520 patients (574 admissions) were included [1999: n = 144 (167); 2008: n = 376 (407)]. Patients received a total of 2053 drugs [median 3, interquartile range (IQR) 2–5]. 19% of patients did not receive any medication. Median length of stay was 4 days (IQR 3–7; range 1–190 days) with a significantly longer length of stay in 1999. The overall ADR incidence was 13.1% (95% CI, 9.8–16.3) varying significantly between the two study cohorts [1999: 21.9%, 95% CI, 14.7–29.0; 2008: 9.2%, 95% CI, 5.9–12.5 (p<0.001)]. Antibacterials and corticosteroids for systemic use caused most of the ADRs in both cohorts (1999; 2008). Exposure to systemic antibacterials decreased from 62.9% to 43.5% whereas exposure to analgesics and anti-inflammatory drugs increased from 17.4% to 45.2%, respectively. The use of high risk drugs decreased from 75% to 62.2%. In 1999, 45.7% and in 2008 96.2% of ADRs were identified by treating clinicians (p<0.001). Conclusions Between 1999 and 2008, the incidence of ADRs decreased significantly. Improved treatment strategies and an increased awareness of ADRs by physicians are most likely to be the cause for this positive development. Nevertheless further research on ADRs particularly in primary care and the establishment of prospective pharmacovigilance systems are still

  5. Results of treatment with azacitidine in patients aged ≥ 75 years included in the Spanish Registry of Myelodysplastic Syndromes.

    PubMed

    Xicoy, Blanca; Jiménez, María-José; García, Olga; Bargay, Joan; Martínez-Robles, Violeta; Brunet, Salut; Arilla, María-Jesús; Pérez de Oteyza, Jaime; Andreu, Rafael; Casaño, Francisco-Javier; Cervero, Carlos-Javier; Bailén, Alicia; Díez, María; González, Bernardo; Vicente, Ana-Isabel; Pedro, Carme; Bernal, Teresa; Luño, Elisa; Cedena, María-Teresa; Palomera, Luis; Simiele, Adriana; Calvo, José-Manuel; Marco, Víctor; Gómez, Eduardo; Gómez, Marta; Gallardo, David; Muñoz, Juan; de Paz, Raquel; Grau, Javier; Ribera, Josep-Maria; Benlloch, Luis-Enrique; Sanz, Guillermo

    2014-06-01

    The tolerability of azacitidine (AZA) allows its administration in elderly patients. The objective of this study was to analyze the clinical and biological characteristics, transfusion independence (TI), overall survival (OS) and toxicity in a series of 107 patients ≥ 75 years of age from the Spanish Registry of Myelodysplastic Syndromes (MDS) treated with AZA. The median age (range) was 78 (75-90) years. According to the World Health Organization (WHO) classification, 86/102 (84%) had MDS, 10/102 (10%) had mixed myeloproferative/myelodysplastic disorder and 6/102 (6%) had acute myeloblastic leukemia. Regarding MDS by the International Prognostic Scoring System on initiation of AZA, 38/84 (45%) were low-intermediate-1 risk and 46/84 (55%) were intermediate-2-high risk. Ninety-five patients (89%) were red blood cell or platelet transfusion dependent. The AZA schedule was 5-0-0 in 39/106 (37%) patients, 5-2-2 in 36/106 (34%) patients and 7 consecutive days in 31/106 (29%) patients. The median number of cycles administered was 8 (range, 1-30). Thirty-eight out of 94 (40%) patients achieved TI. Median OS (95% confidence interval [CI]) was significantly better in patients achieving TI (n = 38) compared to patients who did not (n = 56) (22 [20.1-23.9] months vs. 11.1 [4.8-17.5] months, p = 0.001). No significant differences were observed in TI rate and OS among the three different schedules. With a median follow-up of 14 (min-max, 1-50) months, the median OS (95% CI) of the 107 patients was 18 (12-23) months and the probability of OS (95% CI) at 2 years was 34% (22-46%). Cycles were delayed in 31/106 (29%) patients and 47/101 patients (47%) were hospitalized for infection. These results show that treatment with AZA was feasible and effective in this elderly population, with 40% achieving TI, having a better OS than patients not achieving it. The schedule of AZA administration did not affect efficacy and toxicity.

  6. Results at seven years after the use of intracamerular cefazolin as an endophthalmitis prophylaxis in cataract surgery

    PubMed Central

    2012-01-01

    Background To evaluate results after seven years using prophylactic intracameral cefazolin for the prevention of endophthalmitis in cataract surgery. Methods A prospective, observational study of all patients submitted to cataract surgery over the period January 1996 to December 2009. All cases of postoperative endophthalmitis over that period were reviewed. The patients were classified in two groups: Group 1 (11,696 patients) operated on between January 1996 and December 2002, Group 2 (13,305 patients) between January 2003 and December 2009 (in whom a 1 mg/0.1 bolus of intracameral cefazolin was instilled). Results During the study period, 76 cases of endophthalmitis were observed in Group 1, and seven in Group 2. The rate of postoperative endophthalmitis reduced from 0.63% to 0.05% with a cefazolin injection. The relative risk (RR) for endophthalmitis in Group 1 against group 2 was 11.45 [95% CI 5.72-22.84, p < 0.001]. Conclusions An intracameral bolus injection of cefazolin (1 mg in 0.1 ml solution) at the conclusion of the cataract surgery significantly reduced the rate of postoperative endophthalmitis. PMID:22272570

  7. Statistical analyses of the results of 25 years of beach litter surveys on the south-eastern North Sea coast.

    PubMed

    Schulz, Marcus; Clemens, Thomas; Förster, Harald; Harder, Thorsten; Fleet, David; Gaus, Silvia; Grave, Christel; Flegel, Imme; Schrey, Eckart; Hartwig, Eike

    2015-08-01

    In the North Sea, the amount of litter present in the marine environment represents a severe environmental problem. In order to assess the magnitude of the problem and measure changes in abundance, the results of two beach litter monitoring programmes were compared and analysed for long-term trends applying multivariate techniques. Total beach litter pollution was persistently high. Spatial differences in litter abundance made it difficult to identify long-term trends: Partly more than 8000 litter items year(-1) were recorded on a 100 m long survey site on the island of Scharhörn, while the survey site on the beach on the island of Amrum revealed abundances lower by two orders of magnitude. Beach litter was dominated by plastic with mean proportions of 52%-91% of total beach litter. Non-parametric time series analyses detected many significant trends, which, however, did not show any systematic spatial patterns. Cluster analyses partly led to groupings of beaches according to their expositions to sources of litter, wind and currents. Surveys in short intervals of one to two weeks were found to give higher annual sums of beach litter than the quarterly surveys of the OSPAR method. Surveys at regular intervals of four weeks to five months would make monitoring results more reliable.

  8. Hybrid Therapy in Patients with Complex Peripheral Multifocal Steno-obstructive Vascular Disease: Two-Year Results

    SciTech Connect

    Cotroneo, Antonio Raffaele; Iezzi, Roberto Marano, Giuseppe; Fonio, Paolo; Nessi, Franco; Gandini, Giovanni

    2007-06-15

    Purpose. To report the 2-year results after hybrid (combined surgical-endovascular) therapy in patients with complex peripheral multifocal steno-obstructive vascular disease. Methods. From September 2001 through April 2003, 47 combined surgical-endovascular procedures were performed in a single session in 44 patients with peripheral occlusive artery disease. Although the common femoral artery is usually treated with open surgery, endoluminal procedures were performed upward in 23 patients (group A), distally in 18 patients (group B), and both upward and downward of the area treated with open surgery in 3 patients (group C). Patients underwent clinical assessment and color duplex ultrasonography examination at 1, 3, 6, 12, 18, and 24 months after the procedure. Results. The technical success rate was 100%. Two patients died, at 2 and 19 months after treatment, respectively, both from myocardial infarction. Primary and primary-assisted patency rates were 86.2% and 90.8% at 6 months and 79.1% and 86.1% at 24 months, respectively. Thirty-three patients remained free of symptoms, without any secondary interventions, which corresponded to a primary patency rate of 78.6% (33 of 42). Conclusion. Combined therapy simplifies and allows the one-step treatment of patients with complex peripheral multifocal steno-obstructive vascular disease that has indications for revascularization, and it provides excellent long-term patency rates.

  9. Is it possible and worth keeping track of deaths within general practice? Results of a 15 year observational study

    PubMed Central

    Beaumont, B; Hurwitz, B

    2003-01-01

    Aim: To assess the value of maintaining a death register in a general practice with particular reference to monitoring quality of care. Design of study: Observational study. Setting: Inner London general practice. Method: The practice maintained a manual death register, retained medical records of all deceased patients, and requested information on cause of death from health authorities and coroners for 15 years. Main outcome measures: Number and causes of deaths; 3 yearly age standardised death rates; proportion of deaths formally notified to the practice; place of death; source of cause of death information. Results: During the study period 578 patients died. Practice age standardised death rates fell significantly from 35.59 to 27.12/1000. 498 (86.2%) deaths were formally notified to the practice, 392 within 7 days of death. Of 143 deaths reported to the coroner, only 45 coroners' reports were received. 360 (64.1%) died in hospital, 139 (24.8%) at home, and 38 (6.8%) in a hospice. Death certificate cause of death information was obtained from patients' records in 33.6% (n=194) of cases and from health authority sources for 50% (n=289). The pattern of ascertained causes of deaths was similar to the national pattern. Conclusion: A death register can examine trends in practice deaths by age and place of death and comparisons undertaken with nationally published mortality data. An accurate picture of cause of death cannot be generated from routine data flows alone. There is delay in informing GPs of patient deaths. Meaningful and timely monitoring of deaths cannot be undertaken by individual practices. National Statistics should provide routine analysis of GP death certificate information. PMID:14532364

  10. Evaluating long-term effects of heroin-assisted treatment: the results of a 6-year follow-up.

    PubMed

    Güttinger, Franziska; Gschwend, Patrick; Schulte, Bernd; Rehm, Jürgen; Uchtenhagen, Ambros

    2003-04-01

    Since January 1994, heroin-assisted treatment for opiate addicts has been available in Switzerland. This is the first report of the long-term effects of this form of treatment. The report examines subjects who entered a study involving medical prescription of opiates (Projekt zur ärztlichen Verschreibung von Betäubungsmitteln; PROVE) in Switzerland between January 1994 and March 1995 (n = 366). Opiates were dispensed in eight treatment centres. A follow-up was conducted 6 years after treatment entry. Two groups were assessed: clients who have continuously been on heroin-assisted treatment since entry into the PROVE study or who re-entered this treatment, and ex-clients who had discontinued heroin-assisted treatment at the time of follow-up. Two kinds of comparisons were conducted. Firstly, conditions at treatment entry were compared to 6-year follow-up outcomes, and secondly, outcomes were compared between clients still on heroin-assisted treatment and those who had been discharged. It was found that 46% of the clients still alive were on heroin-assisted treatment at the time of follow-up. A comparison of the present living conditions showed very little difference between those in treatment and those who had terminated treatment. Compared to the situation at entry, the results of the follow-up showed a significant decrease in the use of illegal substances, illegal income and most other variables concerning social conditions, but they also showed an increase in unemployment and reliance on social benefits. Heroin-assisted treatment is thus efficacious in the long-term course of treatment and is still effective after termination of treatment with respect to living conditions and use of illicit substances.

  11. 10-Year Experience With I-125 Prostate Brachytherapy at the Princess Margaret Hospital: Results for 1,100 Patients

    SciTech Connect

    Crook, Juanita; Borg, Jette; Evans, Andrew; Toi, Ants; Saibishkumar, E.P.; Fung, Sharon; Ma, Clement

    2011-08-01

    Purpose: To report outcomes for 1,111 men treated with iodine-125 brachytherapy (BT) at a single institution. Methods and Materials: A total of 1,111 men (median age, 63) were treated with iodine-125 prostate BT for low- or intermediate-risk prostate cancer between March 1999 and November 2008. Median prostate-specific antigen (PSA) level was 5.4 ng/ml (range, 0.9-26.1). T stage was T1c in 66% and T2 in 34% of patients. Gleason score was 6 in 90.1% and 7 or 8 in 9.9% of patients. Neoadjuvant hormonal therapy (2-6 months course) was used in 10.1% of patients and combined external radiotherapy (45 Gy) with BT (110 Gy) in 4.1% (n = 46) of patients. Univariate and multivariate Cox proportional hazards were used to determine predictors of failure. Results: Median follow-up was 42 months (range, 6-114), but for biochemical freedom from relapse, a minimum PSA test follow-up of 30 months was required (median 54; n = 776). There were 27 failures, yielding an actuarial 7-year disease-free survival rate of 95.2% (96 at risk beyond 84 months). All failures underwent repeat 12-core transrectal ultrasound -guided biopsies, confirming 8 local failures. On multivariate analysis, Gleason score was the only independent predictor of failure (p = 0.001; hazard ratio, 4.8 (1.9-12.4). Median International Prostate Symptom score from 12 to 108 months ranged between 3 and 9. Of the men reporting baseline potency, 82.8% retained satisfactory erectile function beyond 5 years. Conclusion: Iodine-125 prostate BT is a highly effective treatment option for favorable- and intermediate-risk prostate cancer and is associated with maintenance of good urinary and erectile functions.

  12. Early Results of Three-Year Monitoring of Red Wood Ants’ Behavioral Changes and Their Possible Correlation with Earthquake Events

    PubMed Central

    Berberich, Gabriele; Berberich, Martin; Grumpe, Arne; Wöhler, Christian; Schreiber, Ulrich

    2013-01-01

    Simple Summary For three years (2009–2012), two red wood ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), have been monitored 24/7 by high-resolution cameras. Early results show that ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants’ behavior hours before the earthquake: the nocturnal rest phase and daily activity are suppressed, and standard daily routine does not resume until the next day. At present, an automated image evaluation routine is being applied to the video streams. Based on this automated approach, a statistical analysis of the ant behavior will be carried out. Abstract Short-term earthquake predictions with an advance warning of several hours or days are currently not possible due to both incomplete understanding of the complex tectonic processes and inadequate observations. Abnormal animal behaviors before earthquakes have been reported previously, but create problems in monitoring and reliability. The situation is different with red wood ants (RWA; Formica rufa-group (Hymenoptera: Formicidae)). They have stationary mounds on tectonically active, gas-bearing fault systems. These faults may be potential earthquake areas. For three years (2009–2012), two red wood ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), have been monitored 24/7 by high-resolution cameras with both a color and an infrared sensor. Early results show that ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants’ behavior hours before the earthquake: the nocturnal rest phase and daily activity are suppressed, and standard daily routine does not resume until the next day. At present, an automated image evaluation routine is being applied to the more than 45,000 hours of video streams. Based on this automated approach, a statistical analysis of

  13. Scoliosis screening results of primary school students (11–15 years old group) in the west side of Istanbul

    PubMed Central

    Çolak, Tuğba Kuru; Apti, Adnan; Dereli, E.Elçin; Özdinçler, Arzu Razak; Çolak, İlker

    2015-01-01

    [Purpose] The present study aimed to find out the scoliosis prevalence 11–15 years old children and to create awareness about scoliosis. [Subjects and Methods] All of the children were assessed using the Adams Forward Bendings Test and a scoliometer. Sagittal plane changes such as kyphosis, lordosis, hypokyphosis, hypolordosis and anterior head tilt were screened. Children with trunk rotation angles (ATR) of 4 degrees or more were suspected of having scoliosis, and were evaluated for a second time for gibbosity height, arm-trunk distance, and ATR. [Results] A total of 2,207 children were screened and the evaluation revealed there were 11 girls (0.49%) with a Cobb angle of 10 degrees and more. The maximum Cobb angle was 43° (right thoracic-left lumbar) and the maximum ATR was 12°. Two children had kyphosis and lordosis, and one had hypokyphosis and was diagnosed as having idiopathic scoliosis. [Conclusion] Families should regularly check their children, even if they are not diagnosed as having scoliosis in school screenings. It is our opinion that our study increased the awareness of the families about scoliosis by screening, brochures and posters. In the future, if school screenings were performed as a routine procedure and scoliotic students were followed over the long term, the actual effectiveness of screening would be able to be detected. PMID:26504296

  14. Results from a 3-year deficit irrigation experiment with drip-irrigated maize to improve water productivity

    NASA Astrophysics Data System (ADS)

    Kloss, Sebastian; Schütze, Niels; Grundmann, Jens

    2013-04-01

    Water for irrigation farming is severely limited in arid and semi-arid regions, hence reliable and robust strategies are needed that allow to use the available resources efficiently. Controlled deficit irrigation (DI) is one strategy that can help to use water in an effective way while still ensuring considerable yields from harvest. It needs precise irrigation control however where sensors are used to determine when to irrigate. Therefore, thresholds that trigger irrigation need to be chosen carefully. An irrigation experiment with drip-irrigated maize was conducted in three consecutive years (2010-2012) where different controlled DI strategies were tested. The experiments took place in a greenhouse at TU München in Freising, Germany, and comprised treatments with constant and varying irrigation thresholds throughout the growing season, which were compared to fully irrigated reference treatments. Thresholds were determined in soil tension as it is closely related to the working principle behind plant transpiration and treatments evaluated with regard to their water productivity (WP - yield over applied irrigation water). The irrigation thresholds were determined prior to the experiment by a stochastic simulation-based framework that consisted of a weather generator, the crop growth model Daisy, and an optimization algorithm for finding optimal thresholds under limiting water supply. Achieved results show similar or better WP compared to the reference and generally high WP compared to values from literature which suggests this methodology is a promising approach to improve WP.

  15. One Year Effects of a Workplace Integrated Care Intervention for Workers with Rheumatoid Arthritis: Results of a Randomized Controlled Trial.

    PubMed

    van Vilsteren, M; Boot, C R L; Twisk, J W R; Steenbeek, R; Voskuyl, A E; van Schaardenburg, D; Anema, J R

    2017-03-01

    Purpose To evaluate the effectiveness of a workplace integrated care intervention on at-work productivity loss in workers with rheumatoid arthritis (RA) compared to usual care. Methods In this randomized controlled trial, 150 workers with RA were randomized into either the intervention or control group. The intervention group received an integrated care and participatory workplace intervention. Outcome measures were the Work Limitations Questionnaire, Work Instability Scale for RA, pain, fatigue and quality of life (RAND 36). Participants filled out a questionnaire at baseline, and after 6 and 12 months. We performed linear mixed models to analyse the outcomes. Results Participants were on average 50 years of age, and mostly female. After 12 months, no significant intervention effect was found on at-work productivity loss. We also found no significant intervention effects on any of the secondary outcomes. Conclusions We did not find evidence for the effectiveness of our workplace integrated care intervention after 12 months of follow up. Future studies should focus on investigating the intervention in groups of workers with severe limitations in work functioning, and an unstable work situation.

  16. Results from a seven-year programme of breast self-examination in 89,010 women.

    PubMed Central

    Locker, A. P.; Caseldine, J.; Mitchell, A. K.; Blamey, R. W.; Roebuck, E. J.; Elston, C. W.

    1989-01-01

    This report presents the results of a study into the effect of breast self-examination (BSE) in a large defined population within the City of Nottingham since 1979. We have examined the effect of breast self-examination in a group of patients invited to attend for education in BSE compared with a group of historical controls. No overall survival advantage has been demonstrated for the study group but within the latter group patients who had attended for instruction in BSE had a significantly better actuarial survival at 13 years than those who did not (P less than 0.001). Patients in the study group presented with significantly smaller tumours which were more likely to be of better histological grade and lymph node stage. A case-control study has demonstrated the value of attendance for BSE particularly in post-menopausal women. Although BSE is not as sensitive as mammographic screening, patients who practise it present with more favourable tumour characteristics and its value in post-menopausal women supports its use as an adjunct to mammographic screening. PMID:2789950

  17. Eight-year results of the Spiesser study, a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation.

    PubMed

    Gatault, Philippe; Bertrand, Dominique; Büchler, Matthias; Colosio, Charlotte; Hurault de Ligny, Bruno; Weestel, Pierre-François; Rerolle, Jean-Philippe; Thierry, Antoine; Sayegh, Johnny; Moulin, Bruno; Snanoudj, Renaud; Rivalan, Joseph; Heng, Anne-Elisabeth; Sautenet, Bénédicte; Lebranchu, Yvon

    2016-01-01

    We present the results at 8 years of the Spiesser study, a randomized trial comparing de novo sirolimus and cyclosporine in kidney transplant recipients at low immunologic risk. We assessed estimated glomerular filtration (eGFR), graft, patient, and death-censored graft survival (log-rank compared), de novo DSA appearance, risk of malignancy, post-transplant diabetes mellitus (PTDM), and anemia. Intent-to-treat and on-treatment analyses were performed. Graft survival was similar in both groups (sirolimus: 73.3%, cyclosporine: 77.7, P = 0.574). No difference was observed between treatment groups concerning patient survival (P = 0.508) and death-censored graft survival (P = 0.858). In conditional intent-to-treat analysis, mean eGFR was greater in sirolimus than in cyclosporine group (62.5 ± 27.3 ml/min vs. 47.8 ± 17.1 ml/min, P = 0.004), in particular because graft function was excellent in patients maintained under sirolimus (eGFR = 74.0 ml/min). Importantly, no detrimental impact was observed in patients in whom sirolimus has been withdrawn (eGFR = 49.5 ml/min). Overall, 17 patients showed de novo DSAs, with no difference between the two groups (P = 0.520). Malignancy did not differ by treatment. An initial maintenance regimen based on sirolimus provides a long-term improvement in renal function for kidney transplant patients, especially for those maintained on sirolimus.

  18. Real-driving emissions from cars and light commercial vehicles - Results from 13 years remote sensing at Zurich/CH

    NASA Astrophysics Data System (ADS)

    Chen, Yuche; Borken-Kleefeld, Jens

    2014-05-01

    We report on long-term remote sensing measurements of light duty vehicle emissions at one site close to Zurich/Switzerland. The time series of annual measurements at the same site between 2000 and 2012, the same season, and virtually the same instrument is unique, probably worldwide. We analyze the development of unit exhaust emissions from model years 1985 until 2012, covering all five Euro emission limit stages in force. NOx emissions from both diesel cars and light commercial vehicles have actually increased in real-driving over time although emission limits have been progressively tightened. This behavior is explained mostly by a significant discrepancy between engine conditions during real-driving and the homologation test procedure. This discrepancy is not important for the other pollutants or for gasoline light duty vehicles, for which the emission control equipment is found working over a wide range of engine conditions. Our results confirm emission factors from the latest HBEFA model when deterioration and engine load are accounted for. Recent remote sensing measurements of diesel cars and light commercial vehicles in London are at the same or higher levels. However, given that engine load is much lower in London, this coincidence is rather puzzling. A key uncertainty is the amount of primary NO2 in the exhaust, and potential systematic differences between dominant brands in European countries. Both needs further investigation.

  19. SU-E-I-90: Medical Physicists' Implication in Diagnostic CT in Switzerland: Results of After One Year of Experience

    SciTech Connect

    Ryckx, N.; Elandoy, C.; Bize, J.; Verdun, F.R.

    2014-06-01

    Purpose: Since January 1st 2008, the Swiss ordinance on radiation protection requires the involvement of a medical physicist to support the optimization process of medical imaging techniques using ionizing radiation. After a long process of implementation, this requirement is satisfied all over the country since the beginning of 2013. The goal of this contribution is to summarize the main results obtained in this first year of experience in CT. Methods: We assessed the output and clinical use of 45 CT units using a three-pronged approach. First, we assessed the output of the device (CTDIvol, primary beam collimation and HU in water at different tube tensions). Secondly, we characterized the local chest and abdomen acquisition and reconstruction protocols using the Catphan 600 phantom. Lastly, we assessed the clinical use of the machine by analyzing an extract of a dozen clinical examinations per unit. Results: 9 out of 45 units had incorrect collimator settings, e.g. 4mm instead of 1mm. We witnessed also a large spread in reconstruction parameters, especially for reconstructed slice thickness, thus showing notable variations in low contrast detectability performances. Clinical practice is also clearly spread out. For example, estimated patient effective dose per abdomen examination lies at 18.7+/−12.7mSv (min: 2.0mSv — max: 112.0mSv). Chest and brain scans have a narrower dispersion, but patient effective dose is also spread by about a factor of 10 to 20. Conclusion: The spread in clinical practice being fairly large, it appears of crucial importance to collaborate more closely with radiologists and technologists to assess it. The lack of statistical precision will imply that we analyze clinical practice according to a specific medical demand rather than an anatomical region. Furthermore, low contrast sensitivity (LCD) being a crucial parameter, an objective method using a model observer will be used to assess LCD.

  20. Refractive, Topographic, and Aberrometric Results at 2-Year Follow-Up for Accelerated Corneal Cross-Link for Progressive Keratoconus

    PubMed Central

    Bozkurt, Ercüment; Akcay, Betul Ilkay Sezgin; Kurt, Tugba; Yildirim, Yusuf; Günaydin, Zehra Karaagaç; Demirok, Ahmet

    2017-01-01

    Purpose. To report the visual, refractive, and corneal topography and wavefront aberration results of accelerated corneal cross-linking (CXL) during a 24-month follow-up. Methods. Forty-seven eyes underwent riboflavin-ultraviolet A-induced accelerated CXL treatment (30 mW/cm2 with a total dose of 7.2 joules/cm2). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical and cylindrical values, keratometry (K) measurements (Ksteep, Kflat, Kavg, and Kapex), central corneal thickness, and anterior corneal aberrometric analyses including total wavefront error (WFE), total high order aberration (HOA), astigmatism, trefoil, coma, quadrafoil, secondary astigmatism, and spherical aberration were evaluated. Results. The mean UDVA and CDVA were significantly improved at 1 (p = 0.003 and p = 0.004, resp.) and 2 years after treatment (p = 0.001 and p = 0.001, resp.). The mean Ksteep, Kflat, Kaverage, and Kapex values were significantly lower than baseline at 12 months (p = 0.008, p = 0.024, p = 0.001, and p = 0.014, resp.) and 24 months (p = 0.014, p = 0.017, p = 0.001, and p = 0.012, resp.). Corneal thickness showed a significant decrease at 1 month. Total HOA and coma decreased significantly at the 12-month (p = 0.001 and p = 0.009, resp.) and 24-month visits (p = 0.001 and p = 0.007, resp.). Conclusion. Accelerated CXL (30 mW/cm2) was found to be effective in improving UDVA, CDVA, corneal topography readings, total HOA, and coma aberrations during the 24-month follow-up. PMID:28197339

  1. Trajectories of Heroin Addiction: Growth Mixture Modeling Results Based on a 33-Year Follow-Up Study

    ERIC Educational Resources Information Center

    Hser, Yih-Ing; Huang, David; Chou, Chih-Ping; Anglin, M. Douglas

    2007-01-01

    This study investigates trajectories of heroin use and subsequent consequences in a sample of 471 male heroin addicts who were admitted to the California Civil Addict Program in 1964-1965 and followed over 33 years. Applying a two-part growth mixture modeling strategy to heroin use level during the first 16 years of the addiction careers since…

  2. Nineteen year results of THA using modular 9 mm S-ROM femoral component in patients with small femoral canals.

    PubMed

    Drexler, Michael; Dwyer, Tim; Marmor, Meir; Abolghasemian, Mansour; Chakravertty, Rajesh; Chechik, Ofir; Cameron, Hugh U

    2013-10-01

    A retrospective analysis was undertaken of 30 consecutive THA performed in 25 patients with hypoplastic proximal femurs, who had received a 9-mm uncemented modular S-ROM stem. The mean patient age was 42 years (17-69 years), mean height was 152.5 cm (130-170.5 cm), mean weight was 63 kg (39-90 kg), and mean follow-up period was 19 years (range, 12-23 years). Subsidence was seen in 2 hips, with asymptomatic femoral osteolysis present in 11 hips; overall survival of the femoral stem was 93.3%, with two revisions of the femoral component required for aseptic loosening. After a mean follow-up of 19 years, the use of the S-ROM 9 mm femoral stem in the patient with the small femur was associated with a low revision rate due to aseptic loosening of the stem.

  3. Erosion Results of the MISSE 8 Polymers Experiment After 2 Years of Space Exposure on the International Space Station

    NASA Technical Reports Server (NTRS)

    de Groh, Kim K.; Banks, Bruce A.; Asmar, Olivia C.; Yi, Grace T.; Mitchell, Gianna G.; Guo, Aobo; Sechkar, Edward A.

    2017-01-01

    Polymers and other oxidizable materials on the exterior of spacecraft in the low Earth orbit (LEO) space environment can be eroded due to reaction with atomic oxygen (AO). Therefore, in order to design durable spacecraft, it is important to know the LEO AO erosion yield (E(sub y), volume loss per incident oxygen atom) of materials susceptible to AO reaction. A spaceflight experiment, called the Polymers Experiment, which contained 42 samples, was developed to determine the effect of solar exposure on the AO E(sub y) of fluoropolymers flown in ram, wake, or zenith orientations. The Polymers Experiment was exposed to the LEO space environment on the exterior of the International Space Station (ISS) as part of the Materials International Space Station Experiment 8 (MISSE 8) mission. The MISSE 8 mission included samples flown in a zenith/nadir orientation for 2.14 years in the MISSE 8 Passive Experiment Container (PEC), and samples flown in a ram/wake orientation for 2.0 years in the Optical Reflector Materials Experiment-III (ORMatEIII) tray. The experiment included Kapton H (Registered Trademark) witness samples for AO fluence determination in each orientation. This paper provides an overview of the MISSE 8 mission, a description of the flight experiment with details on the polymers flown, the characterization techniques used, the AO fluence for each exposure orientation, and the LEO E(sub y) results. The E(sub y) of Teflon fluorinated ethylene propylene (FEP) samples flown in ram, wake, and zenith orientations have been compared, and the E(sub y) was found to be highly dependent on orientation and therefore environmental exposure. The FEP E(sub y) was found to directly correlate with the solar exposure/AO fluence ratio showing the effect of solar radiation and/or heating due to solar exposure on FEP erosion. In addition, back-surface carbon painted FEP (C-FEP) flown in the zenith orientation had a significantly higher E(sub y) than clear FEP or Al-FEP further

  4. Minimum 10 years follow-up surgical results of adolescent idiopathic scoliosis patients treated with TSRH instrumentation

    PubMed Central

    Ates, Bülent; Akalin, Serdar; Citak, Mehmet; Kaya, Alper; Alanay, Ahmet

    2006-01-01

    Last two decades witnessed great advances in the surgical treatment of idiopathic scoliosis. However, the number of studies evaluating the long-term results of these treatment methods is relatively low. During recent years, besides radiological and clinical studies, questionnaires like SRS-22 assessing subjective functional and mental status and life-quality of patients have gained importance for the evaluation of these results. In this study, surgical outcome and Turkish SRS-22 questionnaire results of 109 late-onset adolescent idiopathic scoliosis patients surgically treated with third-generation instrumentation [Texas Scottish Rite Hospital (TSRH) System] and followed for a minimum of 10 years were evaluated. The balance was analyzed clinically and radiologically by the measurement of the lateral trunk shift (LT), shift of head (SH), and shift of stable vertebra (SS). Mean age of the patients was 14.4±1.9 and mean follow-up period was 136.9±12.7 months. When all the patients were included, the preoperative mean Cobb angle of major curves in the frontal plane was 60.8°±17.5°. Major curves that were corrected by 38.7±22.1% in the bending radiograms, postoperatively achieved a correction of 64.0±15.8%. At the last follow-up visit, 10.3°±10.8° of correction loss was recorded in major curves in the frontal plane with 50.5±23.1% final correction rate. Also, the mean postoperative and final kyphosis angles and lumbar lordosis angles were 37.7°±7.4°, 37.0°±8.4°, 37.5°±8.7°, and 36.3°±8.5°, respectively. A statistically significant correction was obtained at the sagittal plane; mean postoperative changes compared to preoperative values were 7.9° and 12.9° for thoracic and lumbar regions, respectively. On the other hand, normal physiological thoracic and lumbar sagittal contours were achieved in 83.5% and 67.9% of the patients, respectively. Postoperatively, a statistically significant correction was obtained in LT, SH, and SS values (P<0

  5. SU-C-BRD-01: Multi-Centre Collaborative Quality Assurance Program for IMRT Planning and Delivery: Year 3 Results

    SciTech Connect

    McNiven, A; Jaffray, D; Letourneau, D

    2015-06-15

    Purpose: A multi-centre quality assurance program was developed to enable quality improvement by coupling measurement of intensity modulated radiotherapy (IMRT) planning and delivery performance for site-specific planning exercises with diagnostic testing. The third year of the program specifically assessed the quality of spine stereotactic body radiotherapy (SBRT) planning and delivery amongst the participating centres. Methods: A spine SBRT planning exercise (24 Gy in 2 fractions) was created and completed by participants prior to an on-site visit. The delivery portion of the on-site visit included spine SBRT plan delivery and diagnostic testing, which included portal image acquisition for quantification of phantom positioning error and multi-leaf collimator (MLC) calibration accuracy. The measured dose was compared to that calculated in the treatment planning system (TPS) using 3%/2mm composite analysis and 3%/3mm gamma analysis. Results: Fourteen institutions participated, creating 17 spine SBRT plans (15 VMAT and 2 IMRT). Three different TPS, two beam energies (6 MV and 6 MV FFF), and four MLC designs from two linac vendors were tested. Large variation in total monitor units (MU) per plan (2494–6462 MU) and dose-volume parameters was observed. The maximum point dose in the plans ranged from 116–149% and was dependent upon the TPS used. Pass rates for measured to planned dose comparison ranged from 89.4–100% and 97.3–100% for 3%/2mm and 3%/3mm criteria respectively. The largest measured MLC error did Result in one of the poorer pass rates. No direct correlation between phantom positioning error and pass rates overall. Conclusion: Significant differences were observed in the planning exercise for some plan and dose-volume parameters based on the TPS used. Standard evaluation criteria showed good agreement between planned and measured dose for all participants, however on an individual plan basis, diagnostic tests were able to identify contributing

  6. Long-Term Protection against Diphtheria in the Netherlands after 50 Years of Vaccination: Results from a Seroepidemiological Study

    PubMed Central

    Swart, E. M.; van Gageldonk, P. G. M.; de Melker, H. E.; van der Klis, F. R.; Berbers, G. A. M.; Mollema, L.

    2016-01-01

    Background and Aims To evaluate the National Immunisation Programme (NIP) a population-based cross-sectional seroepidemiological study was performed in the Netherlands. We assessed diphtheria antitoxin levels in the general Dutch population and in low vaccination coverage (LVC) areas where a relatively high proportion of orthodox Protestants live who decline vaccination based on religious grounds. Results were compared with a nationwide seroepidemiological study performed 11 years earlier. Methods In 2006/2007 a national serum bank was established. Blood samples were tested for diphtheria antitoxin IgG concentrations using a multiplex immunoassay for 6383 participants from the national sample (NS) and 1518 participants from LVC municipalities. A cut-off above 0.01 international units per ml (IU/ml) was used as minimum protective level. Results In the NS 91% of the population had antibody levels above 0.01 IU/ml compared to 88% in the 1995/1996 serosurvey (p<0.05). On average, 82% (vs. 78% in the 1995/1996 serosurvey, p<0.05) of individuals from the NS born before introduction of diphtheria vaccination in the NIP and 46% (vs. 37% in the 1995/1996 serosurvey, p = 0.11) of orthodox Protestants living in LVC areas had antibody levels above 0.01 IU/ml. Linear regression analysis among fully immunized individuals (six vaccinations) without evidence of revaccination indicated a continuous decline in antibodies in both serosurveys, but geometric mean antibodies remained well above 0.01 IU/ml in all age groups. Conclusions The NIP provides long-term protection against diphtheria, although antibody levels decline after vaccination. As a result of natural waning immunity, a substantial proportion of individuals born before introduction of diphtheria vaccination in the NIP lack adequate levels of diphtheria antibodies. Susceptibility due to lack of vaccination is highest among strictly orthodox Protestants. The potential risk of spread of diphtheria within the geographically

  7. First Results of 3 Year Monitoring of Red Wood Ants' Behavioural Changes and Their Possible Correlation with Earthquake Events

    NASA Astrophysics Data System (ADS)

    Berberich, Gabriele; Berberich, Martin; Grumpe, Arne; Wöhler, Christian; Schreiber, Ulrich

    2013-04-01

    Short-term earthquake predictions with an advance warning of several hours or days can currently not be performed reliably and remain limited to only a few minutes before the event. Abnormal animal behaviours prior to earthquakes have been reported previously but their detection creates problems in monitoring and reliability. A different situation is encountered for red wood ants (RWA; Formica rufa-group (Hymenoptera: Formicidae). They have stationary nest sites on tectonically active, gas-bearing fault systems. These faults may be potential earthquake areas and are simultaneously information channels deeply reaching into the crust. A particular advantage of monitoring RWA is their high sensitivity to environmental changes. Besides an evolutionarily developed extremely strong temperature sensitivity of 0.25 K, they have chemoreceptors for the detection of CO2 concentrations and a sensitivity for electromagnetic fields. Changes of the electromagnetic field are discussed or short-lived "thermal anomalies" are reported as trigger mechanisms for bioanomalies of impending earthquakes. For 3 years, we have monitored two Red Wood Ant mounds (Formica rufa-group), located at the seismically active Neuwied Basin (Eifel, Germany), 24/7 by high-resolution cameras equipped with a colour and infrared sensor. In the Neuwied Basin, an average of about 100 earthquakes per year with magnitudes up to M 3.9 occur located on different tectonic fault regimes (strike-slip faults and/or normal or thrust faults). The RWA mounds are located on two different fault regimes approximately 30 km apart. First results show that the ants have a well-identifiable standard daily routine. Correlation with local seismic events suggests changes in the ants' behaviour hours before the earthquake event: The nocturnal rest phase and daily activity are suppressed, and standard daily routine is continued not before the next day. Additional parameters that might have an effect on the ants' daily routine

  8. Probability of acoustic transmitter detections by receiver lines in Lake Huron: results of multi-year field tests and simulations

    USGS Publications Warehouse

    Hayden, Todd A.; Holbrook, Christopher M.; Binder, Thomas; Dettmers, John M.; Cooke, Steven J.; Vandergoot, Christopher S.; Krueger, Charles C.

    2016-01-01

    BackgroundAdvances in acoustic telemetry technology have led to an improved understanding of the spatial ecology of many freshwater and marine fish species. Understanding the performance of acoustic receivers is necessary to distinguish between tagged fish that may have been present but not detected and from those fish that were absent from the area. In this study, two stationary acoustic transmitters were deployed 250 m apart within each of four acoustic receiver lines each containing at least 10 receivers (i.e., eight acoustic transmitters) located in Saginaw Bay and central Lake Huron for nearly 2 years to determine whether the probability of detecting an acoustic transmission varied as a function of time (i.e., season), location, and distance between acoustic transmitter and receiver. Distances between acoustic transmitters and receivers ranged from 200 m to >10 km in each line. The daily observed probability of detecting an acoustic transmission was used in simulation models to estimate the probability of detecting a moving acoustic transmitter on a line of receivers.ResultsThe probability of detecting an acoustic transmitter on a receiver 1000 m away differed by month for different receiver lines in Lake Huron and Saginaw Bay but was similar for paired acoustic transmitters deployed 250 m apart within the same line. Mean probability of detecting an acoustic transmitter at 1000 m calculated over the study period varied among acoustic transmitters 250 m apart within a line and differed among receiver lines in Lake Huron and Saginaw Bay. The simulated probability of detecting a moving acoustic transmitter on a receiver line was characterized by short periods of time with decreased detection. Although increased receiver spacing and higher fish movement rates decreased simulated detection probability, the location of the simulated receiver line in Lake Huron had the strongest effect on simulated detection probability.ConclusionsPerformance of receiver

  9. Testing of Lunar Permanently Shadowed Regions for Water Ice: LEND Results for about Three Years of Observations

    NASA Astrophysics Data System (ADS)

    Sanin, A.; Mitrofanov, I.; Litvak, M.; Boynton, W. V.; Chin, G.; Evans, L. G.; Garvin, J.; Golovin, D.; Harshman, K.; McClanahan, T. R.; Malakhov, A.; Milikh, G. M.; Sagdeev, R.; Starr, R. D.

    2012-12-01

    Introduction: More than 50 years ago, it was sug-gested that some areas near the lunar poles are suffi-ciently cold to trap and preserve for a very long time (~Gy) hydrogen bearing volatiles, either primordial or produced at the Moon via solar wind interactions or brought to the Moon as water ice by comets and mete-oroids [1,2]. The results of observations made by radar onboard the Clementine spacecraft and by neutron (LPNS) and gamma-ray (LPGRS) spectrometers onboard the Lunar Prospector mission have been inter-preted as an enhancement of hydrogen abundance in permanently shadowed regions (PSRs) [3]. Unfortu-nately, the spatial resolution of these instruments were much broader than the size of any largest PSRs [4] requiring model dependent data deconvolution to res-lve signal from PSRs itself. Data Analysis: We would like to present updated results of analysis of Lunar Exploration Neutron Detector (LEND) data for about three years of lunar mapping. Data measured by collimated LEND detectors allows one to look at neutron flux distribution at Moon poles with much better spatial resolution then was achieved at previous space missions. Using the LEND data we had tested the hypothesis that all PSRs are contain a large amount of water ice permafrost and test for hydrogen presents in regolith of regions outside of PSRs. Discussion: Both analyses of individual PSRs and studies of groups of PSRs have shown that these spots of extreme cold at lunar poles are not associated with a strong effect of epithermal neutron flux suppression [5]. We found only three large PSRs, Shoemaker and Cabeus in the South and Rozhdestvensky U in the North, which manifest significant neutron suppression, from -5.5% to -14.9%. All other PSRs have much smaller suppression, no more than few percentages, if at all. Some PSRs even display excess of neutron emis-sion in respect to sunlit vicinity around them. Testing PSRs collectively, we have not found any average suppression for them. Only group of

  10. Aerosol measurements at the Gual Pahari EUCAARI station: preliminary results from first year in-situ measurements

    NASA Astrophysics Data System (ADS)

    Hyvärinen, A.-P.; Lihavainen, H.; Komppula, M.; Panwar, T. S.; Sharma, V. P.; Hooda, R. K.; Viisanen, Y.

    2010-04-01

    The Finnish Meteorogical Institute (FMI), together with The Energy and Resources Institute of India (TERI), contributed to the The European Integrated project on Aerosol Cloud Climate and Air Quality Interactions, EUCAARI, by conducting aerosol measurements in Gual Pahari, India, from December 2007 to January 2010. This paper describes the station setup in detail for the first time and provides 1st year preliminary results from the aerosol in-situ measurements, which include PM and BC masses, aerosol size distribution from 4 nm to 10 μm, and the scattering and absorption coefficients. The seasonal variation of the aerosol characteristics was very distinct in Gual Pahari. The highest concentrations were observed during the winter and the lowest during the rainy season. The average PM10 concentration (at STP conditions) was 177 μg m-3 and the average PM2.5 concentration was 120 μg m-3. A high percentage (4-9%) of the PM10 mass consisted of BC which indicates anthropogenic influence. The percentage of BC was higher during the winter; and according to the diurnal pattern of the BC fraction, the peak occurred during anthropogenic activity times. Another important source of aerosol particles in the area was new particle formation. The nucleated particles grew rapidly reaching the Aitken and accumulation mode size, thus contributing considerably to the aerosol load. The rainy season decreased the average fraction of particle mass in the PM2.5 size range, i.e. of secondary origin. The other removal, or in this case, dilution mechanism was based on convective mixing and boundary layer evolution. This diluted the aerosol when sun radiation and the temperature was high, i.e. especially during the pre-monsoon day time. The lighter and smaller particles were more effectively diluted.

  11. Patterns of care study for brachytherapy: results of the questionnaire for the years 2002 and 2007 in The Netherlands

    PubMed Central

    Slotman, Ben J.; Guedea, Ferran; Ventura, Montse; Londres, Bradley; Francois, Guy

    2011-01-01

    Purpose The goal of the ESTRO Patterns of Care study for Brachytherapy in Europe (PCBE) 2002 was to develop an aid to analyse brachytherapy practices. A 2nd version of the PCB questionnaire was created for 2007. Data over 2007 were collected at the radiotherapy institutions in The Netherlands and compared with those from 2002. The aim of this study is to describe national brachytherapy practices, to demonstrate trends, and to provide data for rational health care planning. Material and methods Data were collected using a web-based questionnaire. For each centre, a local coordinator, responsible for coordinating the questionnaires and support of the further analysis was assigned. Data from the national cancer incidence registry was used for comparison with the data from the 21 Dutch departments. Results There was a decrease in low-dose rate equipment in parallel to an increase in both pulsed-dose rate and high-dose rate equipment. The use of 3D CT and MR based imaging techniques showed a slow rise. The most common clinical procedures were for prostate, gynaecological, and oesophageal tumours. A large increase (146%) in permanent implant prostate applications using 125I seeds was observed. The numbers of oesophageal and gynaecological treatments remained stable. There is concern on the low numbers of cases treated in some institutions for a few complex treatment sites. For head and neck, anal canal, paediatrics, bladder and eye interventions it ranged from 3-20 patients per year per institution. Conclusions The increase in number of patient treated with brachytherapy is in accordance with the increases in cancer incidence. The percentage of all radiotherapy patients treated with brachytherapy (approximately 5%) remained stable. The survey identified certain trends in resources and techniques, as well as areas of expected improvement and possible gain in clinical outcome. Data reported from this survey can be used for further planning of resources, facilities and

  12. Rheumatoid Arthritis and Mortality Among Women During 36 Years of Prospective Follow-Up: Results From the Nurses’ Health Study

    PubMed Central

    SPARKS, JEFFREY A.; CHANG, SHUN-CHIAO; LIAO, KATHERINE P.; LU, BING; FINE, ALEXANDER R.; SOLOMON, DANIEL H.; COSTENBADER, KAREN H.; KARLSON, ELIZABETH W.

    2016-01-01

    Objective To evaluate rheumatoid arthritis (RA) and mortality risk among women followed prospectively in the Nurses’ Health Study (NHS). Methods We analyzed 119,209 women in the NHS who reported no connective tissue disease at enrollment in 1976. Comorbidity and lifestyle data were collected through biennial questionnaires. Incident RA cases were validated by medical records review. Cause of death was determined by death certificate and medical records review. Cox regression models estimated hazard ratios (HRs) and 95% confidence intervals (95% CIs) for all-cause, cardiovascular disease (CVD), cancer, and respiratory disease mortality for women with RA compared to those without RA. Results We validated 964 incident RA cases and identified 28,808 deaths during 36 years of prospective follow-up. Of 307 deaths among women with RA, 80 (26%) were from cancer, 70 (23%) were from CVD, and 44 (14%) were from respiratory causes. Women with RA had increased total mortality (HR 1.40, 95% CI 1.25–1.57) compared to those without RA, independent of mortality risk factors, including smoking. RA was associated with significantly increased respiratory disease mortality (HR 2.06, 95% CI 1.51–2.80) and cardiovascular disease mortality (HR 1.45, 95% CI 1.14–1.83), but not cancer mortality (HR 0.93, 95% CI 0.74–1.15). For women with seropositive RA, respiratory disease mortality was nearly 3-fold higher than among non-RA women (HR 2.67, 95% CI 1.89–3.77). Conclusion Women with RA had significantly increased mortality compared to those without RA. Respiratory disease and cardiovascular disease mortality were both significantly elevated for women with RA. The nearly 3-fold increased relative risk of respiratory disease mortality was observed only for those with seropositive RA. PMID:26473946

  13. One year of downwelling spectral radiance measurements from 100 to 1400 cm-1 at Dome Concordia: Results in clear conditions

    NASA Astrophysics Data System (ADS)

    Rizzi, R.; Arosio, C.; Maestri, T.; Palchetti, L.; Bianchini, G.; Del Guasta, M.

    2016-09-01

    The present work examines downwelling radiance spectra measured at the ground during 2013 by a Far Infrared Fourier Transform Spectrometer at Dome C, Antarctica. A tropospheric backscatter and depolarization lidar is also deployed at same site, and a radiosonde system is routinely operative. The measurements allow characterization of the water vapor and clouds infrared properties in Antarctica under all sky conditions. In this paper we specifically discuss cloud detection and the analysis in clear sky condition, required for the discussion of the results obtained in cloudy conditions. First, the paper discusses the procedures adopted for the quality control of spectra acquired automatically. Then it describes the classification procedure used to discriminate spectra measured in clear sky from cloudy conditions. Finally a selection is performed and 66 clear cases, spanning the whole year, are compared to simulations. The computation of layer molecular optical depth is performed with line-by-line techniques and a convolution to simulate the Radiation Explorer in the Far InfraRed-Prototype for Applications and Development (REFIR-PAD) measurements; the downwelling radiance for selected clear cases is computed with a state-of-the-art adding-doubling code. The mean difference over all selected cases between simulated and measured radiance is within experimental error for all the selected microwindows except for the negative residuals found for all microwindows in the range 200 to 400 cm-1, with largest values around 295.1 cm-1. The paper discusses possible reasons for the discrepancy and identifies the incorrect magnitude of the water vapor total absorption coefficient as the cause of such large negative radiance bias below 400 cm-1.

  14. Ultrasound-guided foam sclerotherapy of great saphenous vein with 2% polidocanol – one-year follow-up results

    PubMed Central

    Osęka, Marcin; Tworus, Robert; Gałązka, Zbigniew

    2016-01-01

    Introduction Ultrasound-guided foam sclerotherapy (UGFS) of varicose veins is a useful treatment option. It is a relatively safe method in the case of limited, small varicose veins. In theory, a justified concern could be raised that the injection of an active drug into the large superficial venous vessels may potentially cause life-threatening consequences. Aim To assess the safety and efficacy of UGFS using a 2% solution of polidocanol (Aethoxysklerol 2%) in the case of great saphenous vein incompetence. Material and methods Fifty-two patients with great saphenous vein incompetence underwent ultrasound-guided foam sclerotherapy. The efficacy criterion was the elimination of reflux measured ultrasonographically and withdrawal or decrease of complaints: 1 week, and 1, 3, 6 and 12 months after the treatment. Complications of sclerotherapy were reported during follow-up. Results Decrease or withdrawal of complaints of chronic venous insufficiency was reported in 96% of cases (50 patients). Disappearance or decrease of varicose veins was noted in all patients (100%). During examination after 12 months, full success of ultrasound was achieved in 38 (73%) cases, and 11 (21%) patients presented a partial desired effect according to the consensus from Tegernsee. Persistence of reflux longer than 1 s in the treated great saphenous vein was reported in 3 (6%) cases. Serious complications, such as deep vein thrombosis, pulmonary embolism, dyspnea, anaphylaxis, or neurological abnormalities, were not recorded. Conclusions Ultrasound-guided foam sclerotherapy of incompetent great saphenous vein and varicosities with 2% polidocanol was found to be an effective and safe method of treatment during 1 year of observation. However, longer observation is necessary. PMID:27458485

  15. Lymphoma in patients treated with anti-TNF: results of the 3-year prospective French RATIO registry

    PubMed Central

    Mariette, Xavier; Tubach, Florence; Bagheri, Haleh; Bardet, Michel; Berthelot, Jean-Marie; Gaudin, Philippe; Heresbach, Denis; Martin, Antoine; Schaeverbeke, Thierry; Salmon, Dominique; Lemann, Marc; Hermine, Olivier; Raphael, Martine; Ravaud, Philippe

    2010-01-01

    Objective To describe cases of lymphoma associated with anti-TNF therapy, identify risk factors, estimate the incidence and compare risks for different anti-TNF agents. Methods We designed a national prospective registry (RATIO) from 2004 to 2006, for collecting all cases of lymphoma in French patients receiving anti-TNF therapy, whatever the indication. We conducted a case-control analysis including two controls treated with anti-TNF per case and an incidence study of lymphoma with the French population used as reference.. Results We collected 38 cases of lymphoma, 31 non-Hodgkin’s lymphoma (NHL) (26 B-cell and 5 T-cell), 5 Hodgkin’s lymphoma (HL) and 2 Hodgkin’s-like lymphoma. Epstein-Barr virus (EBV) was detected in 2 of 2 Hodgkin’s-like lymphoma, 3 of 5 HL and one NHL. Patients receiving adalimumab or infliximab had a higher risk than those treated with etanercept: SIR = 4.1 (2.3–7.1) and 3.6 (2.3–5.6) versus 0.9 (0.4– 1.8). The exposure to adalimumab or infliximab versus etanercept was an independent risk factor for lymphoma in the case-control study: odds ratio=4.7 (1.3– 17.7) and 4.1 (1.4–12.5), respectively. The sex and age- adjusted incidence rate of lymphoma was 42.1 per 100,000 patient-years. The standardized incidence ratio (SIR) was 2.4 (95% confidence interval [CI] 1.7–3.2). Conclusion Some lymphomas associated with immunosuppression may occur in patients receiving anti TNF therapy, and the risk of lymphoma is higher with monoclonal-antibody therapy than with soluble-receptor therapy. PMID:19828563

  16. Erosion Results of the MISSE 7 Polymers Experiment and Zenith Polymers Experiment After 1.5 Years of Space Exposure

    NASA Technical Reports Server (NTRS)

    De Groh, Kim K.; Banks, Bruce A.; Yi, Grace T.; Haloua, Athena; Imka, Emily C.; Mitchell, Gianna G.; Asmar, Olivia C.; Leneghan, Halle A.; Sechkar, Edward A.

    2016-01-01

    Polymers and other oxidizable materials on the exterior of spacecraft in the low Earth orbit (LEO) space environment can be eroded due to reaction with atomic oxygen (AO). Therefore, in order to design durable spacecraft it is important to know the LEO AO erosion yield (E(sub y), volume loss per incident oxygen atom) of materials susceptible to AO reaction. Two spaceflight experiments, the Polymers Experiment and the Zenith Polymers Experiment, were developed to determine the AO E(sub y) of various polymers flown in ram, wake or zenith orientations in LEO. These experiments were flown as part of the Materials International Space Station Experiment 7 (MISSE 7) mission for 1.5 years on the exterior of the International Space Station (ISS). The experiments included Kapton H(TradeMark) witness samples for AO fluence determination in ram and zenith orientations. The Polymers Experiment also included samples to determine whether AO erosion of high and low ash containing polymers is dependent on fluence. This paper provides an overview of the MISSE 7 mission, a description of the flight experiments with details on the polymers flown, the characterization techniques used, the AO fluence for each exposure orientation, and the LEO E(sub y) results. The E(sub y) values ranged from 7.99x10(exp -28)cu cm/atom for TiO2/Al2O3 coated Teflon(TradeMark) fluorinated ethylene propylene (FEP) flown in the ram orientation to 1.22x10(exp -23cu cm/atom for polyvinyl alcohol (PVOH) flown in the zenith orientation. The E(sub y) of similar samples flown in different orientations has been compared to help determine solar exposure and associated heating effects on AO erosion. The E(sub y) data from these ISS spaceflight experiments provides valuable information for LEO spacecraft design purposes.

  17. Familial factors related to lung function in children aged 6-10 years. Results from the PAARC epidemiologic study.

    PubMed

    Kauffmann, F; Tager, I B; Muñoz, A; Speizer, F E

    1989-06-01

    Familial factors related to lung function between six and 10 years of age have been studied among 1,160 children whose both parents were examined in 1975 in the French PAARC (Pollution Atmosphérique et Affections Respiratoires Chroniques) Cooperative Study. The three indices FVC (forced vital capacity), FEV1 (forced expiratory volume in one second), and FEF25-75 (forced expiratory flow between 25 and 75 per cent of the vital capacity) were studied after adjustment for sex, town, age, and height (and weight for children's FVC and FEV1). Maternal (but not paternal) smoking was associated with a significant decrease in FEV1 and FEF25-75, but not in FVC. Familial resemblance was observed for all indices between children and parents and between siblings. None of the environmental factors considered (i.e., parental smoking or education) or body habitus explained the familial resemblance observed. Conversely, after taking into account the aggregation between siblings, associations between children's lung function and parental characteristics (smoking, lung function) remained significant. Parental-children correlations exhibited an increasing temporal trend with increasing age of the children. All but one correlation for FVC, FEV1, and FEF25-75 residuals of children with mothers' residuals were higher in the oldest age group compared with the youngest age group at the 0.10 level. Furthermore, correlations between siblings of opposite sex were significantly lower than correlations between siblings of like sex, especially for FEV1/FVC and FEF25-75/FVC. Results suggest that different growth patterns between boys and girls may be a critical factor in the study of lung function familial resemblance.

  18. Deep Vadose Zone Treatability Test for the Hanford Central Plateau. Interim Post-Desiccation Monitoring Results, Fiscal Year 2015

    SciTech Connect

    Truex, Michael J.; Strickland, Christopher E.; Oostrom, Martinus; Johnson, Christian D.; Tartakovsky, Guzel D.; Johnson, Timothy C.; Clayton, Ray E.; Chronister, Glen B.

    2015-09-01

    A field test of desiccation is being conducted as an element of the Deep Vadose Zone Treatability Test Program. The active desiccation portion of the test has been completed. Monitoring data have been collected at the field test site during the post-desiccation period and are reported herein. This is an interim data summary report that includes about 4 years of post-desiccation monitoring data. The DOE field test plan proscribes a total of 5 years of post-desiccation monitoring.

  19. Evolution of the concept of Capacity-building, results achieved during the past years and the future

    NASA Astrophysics Data System (ADS)

    Laffaiteur, M.; Camacho, S.

    Capacity-building is one of the key elements for the implementation of space applications programmes, particularly in developing countries. As early as 1982, the work programme of the United Nations Programme on Space Applications was expanded in order to promote education and training by organizing seminars, training courses and workshops in various areas, such as astronomy, telecommunications and Earth observation. In the framework of this Programme, the Office for Outer Space Affairs undertook the initiative, at the beginning of the 1990's, aimed at establishing regional centres for space science and technology education, affiliated to the United Nations and located in developing countries. These centres have started their activities between 1995 and 2000 in Africa, Asia and the Pacific, and Latin America and the Caribbean. The centres are based on the concept that by pooling material and human resources, developing countries can have education and training centres, of an international-level quality. A considerable impetus has been given to capacity-building after the UNISPACE III Conference, in particular in the "Vienna Declaration on Space and Human Development". The necessity to enhance capacity-building through the development of human and budgetary resources, the training of teachers, the exchange of teaching methods, materials and experience and the development of infrastructure and policy regulatories. In the process of the implementation of the recommendations of UNISPACE III, Action Teams led by Governments were established. One of them was exclusively dealing with capacity-building. Its proposals have been reviewed last June by the Committee on the Peaceful Uses of Outer Space (COPUOS) and will be examined, among other reports of Action Teams, by the General Assembly in next October. A lot of work has been done during the past years and have produced very important results. But there is still an important gap in capacity-building between space

  20. Stereotactic radiosurgery for vestibular schwannomas: average 10-year follow-up results focusing on long-term hearing preservation.

    PubMed

    Watanabe, Shinya; Yamamoto, Masaaki; Kawabe, Takuya; Koiso, Takao; Yamamoto, Tetsuya; Matsumura, Akira; Kasuya, Hidetoshi

    2016-12-01

    serviceable hearing before SRS who were followed up, hearing acuity was preserved in 23 (35%). Actuarial serviceable hearing preservation rates were 49%, 24%, and 12% at the 60th, 120th, and 180th post-SRS month, respectively. On univariable analysis, only cystic-type tumor (HR 3.36, 95% CI 1.18-9.36; p = 0.02) was shown to have a significantly unfavorable association with FP. Multivariable analysis followed by univariable analysis revealed that higher age (≥ 65 years: HR 2.66, 95% CI 1.16-5.92; p = 0.02), larger tumor volume (≥ 8 cm(3): HR 5.36, 95% CI 1.20-17.4; p = 0.03), and higher cochlear dose (mean cochlear dose > 4.2 Gy: HR 2.22, 95% CI 1.07-4.77; p = 0.03) were unfavorable factors for hearing preservation. CONCLUSIONS Stereotactic radiosurgery achieved good long-term results in this series. Tumor control was acceptable, and there were few serious complications in patients with small- to medium-sized VSs. Unfortunately, hearing preservation was not satisfactory. However, the longer the observation period, the more important it becomes to compare post-SRS hearing decreases with the natural decline in untreated cases.

  1. [Results of self image studies in children and adolescents (11/12-years-old to 16/17-years-old)].

    PubMed

    Göth, N

    1978-02-01

    The author in his present paper reports the results of studies made in an effort to reconstructively validate a method of self-imaging during childhood and adolescence. From the investigative results obtained it is apparent that during adolescence large self-image/ideal-image differences and low self-image values correlate with neuroticism, a situation which is similar to that which is usually observed in adults. Timid and introverted juveniles differ significantly from less timid and extroverted juveniles in both the self-image level and the self-image/ideal-image difference. Aside from the fact that the self-image level has been found to be relatively independent of intelligence, there are correlations between the maternal and child's self-image. It is of interest to note that the self-image level of children whose parents got a divorce is lower than that of children coming from intact families.

  2. [Adenotonsillectomy: the evaluation of the long-term results after more than 7 years from the intervention].

    PubMed

    Esposito, E; Pucci, V; Mesolella, M; Motta, S

    1992-01-01

    A study was carried out on 110 patients with various diseases related to chronic inflammation of the tonsils and to hypertrophic adenoids. Sixty-two of these patients underwent adenotonsillectomy, while the others were followed clinically and, where necessary, given medical treatment. At the first observation the patients were between the ages of 2 and 12 (mean age 6.1 years). At the start of the present study the patients ages ranged from 10 to 22 (mean age 17 years). Clinical follow-up was carried out on the patients 2 and 7 years after the first observation and/or adenotonsillectomy. The patients were divided into homogeneous groups according to the severity of symptoms. The A.A. evaluated changes of the following clinical parameters: annual frequency of inflammatory pharyngotonsillar episodes, nasal respiratory obstruction, sore throat, otologic pathology. Evaluations were carried out statistically in each group. After more than 7 years from surgery, the significant reduction of various diseases related to chronic inflammation of the tonsils and to hypertrophic adenoids, in accordance with the findings after 2 years from surgery, underline the effectiveness of adenotonsillectomy in correctly selected candidates.

  3. Land use mix and five-year mortality in later life: Results from the Cognitive Function and Ageing Study

    PubMed Central

    Wu, Yu-Tzu; Prina, A. Matthew; Jones, Andy; Barnes, Linda E.; Matthews, Fiona E.; Brayne, Carol; MRC CFAS

    2016-01-01

    This study explores the potential modifying effect of age and mediation effect of co-morbidity on the association between land use mix, a measure of neighbourhood walkability, and five-year mortality among the 2424 individuals participating in the year-10 follow-up of the Cognitive Function and Ageing Study in England. Postcodes of participants were mapped onto Lower-layer Super Output Areas, a small area level geographical unit in the UK, and linked to Generalised Land Use data. Cox regression models were fitted to investigate the association. For the younger older age group (75–79 years), the effect of high land use mix on an elevated risk of mortality was mediated by co-morbidity. For older old age groups (80–84, 85+ years), a higher land use mix was directly associated with a 10% lower risk of five-year mortality. The findings suggest differential impacts of land use mix on the health of the younger and older old. PMID:26798962

  4. Thermal regime and potential bedrock weathering in alpine rockwalls of Austria: Results from eight years of monitoring (2006-2014)

    NASA Astrophysics Data System (ADS)

    Kellerer-Pirklbauer, Andreas; Wecht, Matthias

    2015-04-01

    FTC and eFTC was lowest during the hydrological year 06/07 (snow poor and warm winter) whereas highest in 11/12 (snow poor but rather cool winter). In contrast, results are completely different at two substantially higher-elevated but also north-exposed RTS (2639 and 2700 m asl) with highest FTC values in 06/07 and lowest in 11/12. Furthermore, at the two flat bedrock sites (at 2603 and 2650 m asl) the number of FTC and eFTC was highest in 06/07 related to the thin and short winter snow cover. The latter observation suggests that supposed warmer and snow-poor winters in the future will enhance diurnal freeze-thaw cycles and the intensity of near-surface physical weathering in the bedrock of the Austrian Alps. This seems to be feasible at least for elevations above c.2600 m asl.

  5. Results of one year of observations of Solar Flares made by "Solar X-ray Spectrometer (SOXS)" Mission

    NASA Astrophysics Data System (ADS)

    Jain, R.; Dave, H.; Kumar, S.; Deshpande, M. R.

    The first space borne solar astronomy experiment of India namely ``Solar X-ray Spectrometer (SOXS) mission has completed one year of its successful operation in geostationary orbit. The SOXS mission onboard GSAT-2 Indian spacecraft was launched successfully by GSLV-D2 rocket on 08 May 2003 to study the energy release and particle acceleration in solar flares. We briefly present the scientific objectives and instrumentation of the SOXS mission. The SOXS is composed of two independent payloads viz. SOXS Low Energy Detector (SLD) payload, and SOXS High Energy Detector (SHD) payload. We restrict our presentation to SLD payload that designed, developed and fabricated by Physical Research Laboratory (PRL) in collaboration with Space Application Centre (SAC), Ahmedabad and ISRO Satellite Centre (ISAC), Bangalore of Indian Space Research Organization (ISRO). The SLD payload employs the state-of-the-art solid state detectors viz. Si PIN and Cadmium-Zinc-Telluride (CZT) devices that operate at near room temperature (-20 ^0 C). The dynamic energy range of Si PIN and CZT detectors are 4-25 and 4-56 keV. The Si PIN provides sub-keV energy resolution while CZT reveals ˜ 2 keV energy resolution throughout the dynamic range. The instrument has onboard flare triggering logic software and 5 MB-memory bank. The data is transmitted to Master Control Facility (MCF), Hasan with 8 kbps telemetry rate. The observations are made in fixed energy windows (temporal) mode and in spectral mode with 100ms cadence during the flare. The SLD has observed more than 140 flares of C and M class since its commissioning in the orbit. We present the preliminary results and the X-ray emission characteristics of these flares, and a detailed study of a few typical solar flares, which are impulsive but associated with CMEs, in view of energy release and particle emission by them. The high sensitivity of the SLD and sub-keV energy resolution of Si PIN detector allows the intensity and mean energy of the Fe

  6. THE YOUNG SOLAR ANALOGS PROJECT. I. SPECTROSCOPIC AND PHOTOMETRIC METHODS AND MULTI-YEAR TIMESCALE SPECTROSCOPIC RESULTS

    SciTech Connect

    Gray, R. O.; Briley, M. M.; Lambert, R. A.; Fuller, V. A.; Newsome, I. M.; Seeds, M. F.; Saken, J. M.; Kahvaz, Y.; Corbally, C. J.

    2015-12-15

    This is the first in a series of papers presenting methods and results from the Young Solar Analogs Project, which began in 2007. This project monitors both spectroscopically and photometrically a set of 31 young (300–1500 Myr) solar-type stars with the goal of gaining insight into the space environment of the Earth during the period when life first appeared. From our spectroscopic observations we derive the Mount Wilson S chromospheric activity index (S{sub MW}), and describe the method we use to transform our instrumental indices to S{sub MW} without the need for a color term. We introduce three photospheric indices based on strong absorption features in the blue-violet spectrum—the G-band, the Ca i resonance line, and the Hydrogen-γ line—with the expectation that these indices might prove to be useful in detecting variations in the surface temperatures of active solar-type stars. We also describe our photometric program, and in particular our “Superstar technique” for differential photometry which, instead of relying on a handful of comparison stars, uses the photon flux in the entire star field in the CCD image to derive the program star magnitude. This enables photometric errors on the order of 0.005–0.007 magnitude. We present time series plots of our spectroscopic data for all four indices, and carry out extensive statistical tests on those time series demonstrating the reality of variations on timescales of years in all four indices. We also statistically test for and discover correlations and anti-correlations between the four indices. We discuss the physical basis of those correlations. As it turns out, the “photospheric” indices appear to be most strongly affected by emission in the Paschen continuum. We thus anticipate that these indices may prove to be useful proxies for monitoring emission in the ultraviolet Balmer continuum. Future papers in this series will discuss variability of the program stars on medium (days–months) and short

  7. Helping Italian science teachers to make earth and climate active lessons. Results of 3 years support with the ICLEEN project

    NASA Astrophysics Data System (ADS)

    Cattadori, M.

    2013-12-01

    collaboration with the University of Trento dealing with the effectiveness of the service as well as the usability of the graphic user interface (GUI). The present work aims to illustrate the essential features of the service I-cleen and the results achieved during the last three years of operation. It will be display and interpret for the first time data with web traffic, and other data from downloading and publishing documents of the teaching resources and the main outcomes of the above mentioned tests. The purpose of this contribution is to highlight strengths and weaknesses of this experience and potentially able to provide valuable information on the role of today's web based services and online communities to help support teachers in earth and climate sciences subjects.

  8. The four-year functional result after a displaced subcapital hip fracture treated with three different surgical options.

    PubMed

    Mouzopoulos, George; Stamatakos, Michalis; Arabatzi, Helen; Vasiliadis, George; Batanis, George; Tsembeli, Anastasia; Tzurbakis, Mathaios; Safioleas, Michalis

    2008-06-01

    According to the literature, hip function after hip fracture is affected by the type of surgery. Our aim was to determine the correlation between surgical treatment of hip fracture and postoperative function in the elderly. Inclusion criteria were displaced hip fracture and age over 70 years. One hundred and twenty-nine participants were randomly divided into three groups according to the type of the surgical operation they underwent (hemi-arthroplasty [Merete, Berlin, Germany], total arthroplasty [Plus; De Puy, Warsaw, IN, USA] and internal fixation [Richards plate screw; Smith & Nephew, Memphis, TN, USA]). The function of the patients was estimated using the following parameters: the Barthel Index and Harris Hip Score, the range of passive hip motion, the gait speed of individuals, after 1 and 4 years of follow-up. The Barthel Index scores after 4 years of follow-up were 85.3, 82.6, 80.1 after total arthroplasty, hemi-arthroplasty and internal fixation respectively. Similarly, the Harris Hip Scores after 4 years of follow-up were 83.7, 79.5 and 73.6. The range of passive hip motion in the three groups of patients did not differ significantly (p>0.05). Also, patients of the total arthroplasty and hemi-arthroplasty groups walked faster than the patients of the internal fixation group 4 years after discharge (p<0.05). In conclusion, we believe that total hip arthroplasty is the treatment of choice for displaced subcapital hip fractures in patients over 70 years old.

  9. Large Renal Artery Aneurysm Treated with Guglielmi Detachable Coils: Procedural and 4-Year Follow-up Results

    SciTech Connect

    Damascelli, Bruno; Bartorelli, Antonio L.; Ticha, Vladimira; Trabattoni, Daniela; Lanocita, Rodolfo

    2008-07-15

    A large aneurysm of the left renal artery was found incidentally during abdominal ultrasound in a 39-year-old woman with no medical or family history of cardiovascular disease. Vascular pathology with a dysplastic appearance was confirmed by magnetic resonance angiography and the patient was offered transcatheter embolization. Since the position and size of the neck of the aneurysm could not be determined at angiography, detachable platinum coils were used for occlusion. The procedure was performed without complications. During a 4-year follow-up no alterations of renal function, recanalization of the aneurysm, or perfusion defects in the rest of the left renal circulation were noted.

  10. Twelve-year results of a direct-bonded partial prosthesis in a patient with advanced periodontitis: a clinical report.

    PubMed

    Minami, Hiroyuki; Minesaki, Yoshito; Suzuki, Shiro; Tanaka, Takuo

    2012-08-01

    Prosthodontic treatment for patients with advanced periodontitis is a therapeutic challenge. A minimally invasive technique is preferred to preserve the remaining mobile abutment teeth. This report describes the initial clinical treatment and 12-year follow-up of a direct-bonded prosthesis reinforced with a cast metal framework, used as a conservative treatment option to replace periodontally involved maxillary lateral incisors.

  11. Effectiveness of Strategy Training for Struggling English Language Students: Profiles and Results of a Five-year Study

    ERIC Educational Resources Information Center

    Taylor, Josephine A.; Gomez, Julio Cesar; Quintero, Gloria; Nausa, Ricardo; Rey, Luz Libia

    2011-01-01

    This study examines a group of approximately 1,100 English as a foreign language students who attended a tutoring program dedicated to training learners in study skills and language learning strategies. The study covers a five-year period of time during which the tutoring program remained consistent in its focus and organization. Students…

  12. Finnish Parental Involvement Ethos, Health Support, Health Education Knowledge and Participation: Results from a 2-Year School Health Intervention

    ERIC Educational Resources Information Center

    Sormunen, Marjorita; Tossavainen, Kerttu; Turunen, Hannele

    2013-01-01

    A 2-year, participatory action research school health study focused on developing components for home-school partnerships to support children's health learning process. Two intervention schools implemented strengthened health and collaboration-orientated activities; two control schools followed the national core curriculum without extracurricular…

  13. Evaluation of the Children at Risk Program: Results 1 Year after the End of the Program. Research in Brief.

    ERIC Educational Resources Information Center

    Harr