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Sample records for 10-year period methods

  1. [Stability of steroids in plasma over a 10-year period].

    PubMed

    Kley, H K; Schlaghecke, R; Krüskemper, H L

    1985-12-01

    In order to examine whether plasma samples may be used for steroid analysis after long periods of storage, cortisol, testosterone, oestrone and oestradiol were remeasured in samples, which had been analysed 1.3-10.8 years earlier. The method for the measurement of these steroids was unchanged over this period. The results demonstrate that at a temperature of -25 degrees C steroids remained stable. Only cortisol and testosterone concentrations showed a small, insignificant decrease (6-9%) after 3 to 4 years of storage. These differences are well within the range of the precision of the method (interassay variation), which over a period of 11 years was 9.4%, 8.0%, 10.0% and 9.5% for cortisol, testosterone, oestrone and oestradiol, respectively. It is concluded that steroid hormones in human plasma are stable in our laboratory, and that they might be analysed even after more than 10 years of storage at -25 degrees C. PMID:3831227

  2. Retroperitoneal Fibrosis: A Retrospective Clinical Data Analysis of 30 Patients in a 10-year Period

    PubMed Central

    Zhou, Hai-Jiang; Yan, Yong; Zhou, Biao; Lan, Tian-Fei; Wang, Xue-Yan; Li, Chun-Sheng

    2015-01-01

    Background: Retroperitoneal fibrosis (RPF) is an uncommon disease that is characterized by development of fibrosclerotic tissues involving retroperitoneal structures. This study aimed to investigate the clinical features of 30 patients with RPF in a single center in Beijing in a 10-year period. Methods: We retrospectively analyzed clinical data on demographic characteristics, clinical manifestations, laboratory findings, radiological findings, modalities of treatments, outcomes and prognosis of 30 patients with RPF. Patients were treated in Beijing Chao-Yang Hospital between January 2003 and December 2013. Results: The mean age of patients with RPF was 56.7 ± 14.4 years. Twenty-three patients were men and seven patients were women. Acute phase reactants were elevated in most patients. Rheumatic factor was positive in 4/25 (16.0%) patients, and antinuclear antibody was positive in 6/22 (27.3%) patients. Elevation of IgG4 was observed in 9/22 (40.9%) patients. The most common type was I + III (n = 13), followed by I + II + III (n = 12). Five patients undertook an 18F-fluoro-deoxy-D-glucose positron emission tomography examination and increased uptake was detected in four patients. Eight patients received combination therapy with glucocorticoids and tamoxifen. Surgical intervention treatments included intraureteral double-J stent implantation (n = 26), percutaneous nephrostomy (n = 2), open ureterolysis and intraperitonealization of the ureters (n = 5) and laparoscopic ureterolysis and intraperitonealization of the ureters (n = 5). Three patients underwent hemodialysis because of renal failure. Conclusions: Clinical characteristics of RPF patients in our study are similar to those previously reported. Steroids and immunosuppressive therapy combined with ureterolysis could be a viable choice of treatment for RPF. More prospective, multi-center studies with a longer follow-up are warranted. PMID:25758277

  3. Influence of the isolation method on the 10-year clinical behaviour of posterior resin composite restorations.

    PubMed

    Raskin, A; Setcos, J C; Vreven, J; Wilson, N H

    2000-09-01

    The aims of this prospective randomised clinical study were to clinically evaluate a radiopaque, highly filled, hybrid, light-activated resin-based composite for posterior teeth (Occlusin, ICI Dental, Macclesfield, UK and GC Dental, Tokyo, Japan) and compare the performance of restorations placed using rubber dam or cotton roll isolation. One clinician placed 100 (42 Class I and 58 Class II) restorations of the material under investigation. The isolation mode for each restoration was determined randomly: 52 preparations were protected from contamination with cotton rolls and aspiration, and 48 preparations were isolated under rubber dam. At baseline and periodically thereafter (0.5, 1, 2, 3, 4, 5, 6, and 10 years), each composite was evaluated by two practitioners using a modified (USPHS) rating system. After 10 years, 37 restorations were reviewed. The results showed satisfactory clinical performance with and without rubber dam after 10 years. A concern was the number of failures at 10 years due to unsatisfactory proximal contact. The evaluations for the surviving restorations were acceptable but with a large reduction in the percentage with ideal occlusal and proximal anatomy. The 10-year comparison of isolation modes showed no statistically significant differences (Kruskal-Wallis test) for each of the evaluation criteria. Furthermore, survival analysis showed no significant difference between the groups (Mantel-Haenszel method). It was concluded that the 10-year clinical behaviour of the restorations of a posterior composite placed under well-controlled, effective isolation with cotton rolls and aspiration, was not significantly different from the behaviour of restorations placed using rubber dam isolation.

  4. Stability and change in sexual orientation identity over a 10-year period in adulthood.

    PubMed

    Mock, Steven E; Eibach, Richard P

    2012-06-01

    We examined reports of sexual orientation identity stability and change over a 10-year period drawing on data from the National Survey of Midlife Development in the United States (MIDUS I and II) and tested for three patterns: (1) heterosexual stability, (2) female sexual fluidity, and (3) bisexual fluidity. Fifty-four percent of the 2,560 participants were female and the average age was approximately 47 years. At Wave 1, 2,494 (97.42%) reported a heterosexual identity, 32 (1.25%) a homosexual identity, and 34 (1.33%) a bisexual identity and somewhat more than 2% reported a different sexual orientation identity at Wave 2. Although some support for each hypothesis was found, initial sexual orientation identity interacted with gender to predict a more complex pattern. For the sample as a whole, heterosexuality was the most stable identity. For women, bisexuality and homosexuality were equally unstable and significantly less stable than heterosexuality, suggesting that sexual orientation identity fluidity is a pattern that applies more to sexual minority women than heterosexual women. For men, heterosexuality and homosexuality were both relatively stable compared to bisexuality, which stood out as a particularly unstable identity. This pattern of results was consistent with previous findings and helps to address methodological limitations of earlier research by showing the characteristics of a population-based sample of heterosexual, homosexual, and bisexual identified men and women over time.

  5. Effect of meteorology and soil condition on metolachlor and atrazine volatilization over a 10 year period

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A 10-year study was conducted to focus on the impact of soil and climatic factors governing herbicide volatilization from an agricultural field. For the first 5 years, metolachlor [2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl) acetamide] and atrazine [6-chloro-N-ethyl-N’-(1-methyl...

  6. Effect of meteorology and soil condition on metolachlor and atrazine volatilization over a 10 year period

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Volatilization of pesticides can detrimentally affect the environment by contaminating soil and surface waters far away from where the pesticides were applied. A 10-year study was conducted to focus on the impact of soil and climatic factors governing herbicide volatilization from an agricultural f...

  7. Analysis of a single Helicobacter pylori strain over a 10-year period in a primate model.

    PubMed

    Liu, Hui; Fero, Jutta B; Mendez, Melissa; Carpenter, Beth M; Servetas, Stephanie L; Rahman, Arifur; Goldman, Matthew D; Boren, Thomas; Salama, Nina R; Merrell, D Scott; Dubois, Andre

    2015-05-01

    Helicobacter pylori from different individuals exhibits substantial genetic diversity. However, the kinetics of bacterial diversification after infection with a single strain is poorly understood. We investigated evolution of H. pylori following long-term infection in the primate stomach; Rhesus macaques were infected with H. pylori strain USU101 and then followed for 10 years. H. pylori was regularly cultured from biopsies, and single colony isolates were analyzed. At 1-year, DNA fingerprinting showed that all output isolates were identical to the input strain; however, at 5-years, different H. pylori fingerprints were observed. Microarray-based comparative genomic hybridization revealed that long term persistence of USU101 in the macaque stomach was associated with specific whole gene changes. Further detailed investigation showed that levels of the BabA protein were dramatically reduced within weeks of infection. The molecular mechanisms behind this reduction were shown to include phase variation and gene loss via intragenomic rearrangement, suggesting strong selective pressure against BabA expression in the macaque model. Notably, although there is apparently strong selective pressure against babA, babA is required for establishment of infection in this model as a strain in which babA was deleted was unable to colonize experimentally infected macaques.

  8. Marked reduction of anemia during pregnancy over a 10-year period in Montserrat.

    PubMed

    Simmons, W K; Simeon, D T; Bramble, D; Buffonge, C; Gallagher, P

    1996-03-01

    Anemia during pregnancy is associated with adverse outcomes including maternal and perinatal mortality. However, health education and other public health strategies seeking to reduce its prevalence have usually met with only limited success. The study reported here surveyed anemia of pregnancy on the island of Montserrat in 1980, 1985, and 1990. This involved examination of clinic and hospital records for over 90% of all women giving birth on Montserrat in 1980 and 1985, as well as 80% of those giving birth in 1990. This examination showed a dramatic reduction in the prevalence of anemia at the time of the first prenatal visit (a drop from 82% of the study women in 1980 to 23% in 1985 and 19% in 1990) and also a marked drop at three days postpartum (from 91% in 1980 to 41% in 1985 and 39% in 1990). Logistic regression analyses indicated that after controlling for three possible confounding factors (maternal age, parity, and weeks of gestation at first prenatal visit) the difference between the risk of developing anemia during pregnancy in 1980 as compared to 1985 or 1990 was still highly significant. The reasons for the observed drop in anemia's prevalence during the survey period are not entirely clear, partly because of the retrospective nature of the study. However, better nutrition resulting from improvement in the standard of living on Montserrat during the survey period could have been important, as could changes in health education and food supplementation activities. PMID:8919721

  9. Marked reduction of anemia during pregnancy over a 10-year period in Montserrat.

    PubMed

    Simmons, W K; Simeon, D T; Bramble, D; Buffonge, C; Gallagher, P

    1996-03-01

    Anemia during pregnancy is associated with adverse outcomes including maternal and perinatal mortality. However, health education and other public health strategies seeking to reduce its prevalence have usually met with only limited success. The study reported here surveyed anemia of pregnancy on the island of Montserrat in 1980, 1985, and 1990. This involved examination of clinic and hospital records for over 90% of all women giving birth on Montserrat in 1980 and 1985, as well as 80% of those giving birth in 1990. This examination showed a dramatic reduction in the prevalence of anemia at the time of the first prenatal visit (a drop from 82% of the study women in 1980 to 23% in 1985 and 19% in 1990) and also a marked drop at three days postpartum (from 91% in 1980 to 41% in 1985 and 39% in 1990). Logistic regression analyses indicated that after controlling for three possible confounding factors (maternal age, parity, and weeks of gestation at first prenatal visit) the difference between the risk of developing anemia during pregnancy in 1980 as compared to 1985 or 1990 was still highly significant. The reasons for the observed drop in anemia's prevalence during the survey period are not entirely clear, partly because of the retrospective nature of the study. However, better nutrition resulting from improvement in the standard of living on Montserrat during the survey period could have been important, as could changes in health education and food supplementation activities.

  10. Bibliometric analysis of scientific articles published in Brazilian and international orthodontic journals over a 10-year period

    PubMed Central

    Primo, Neudí Antonio; Gazzola, Vivian Bertoglio; Primo, Bruno Tochetto; Tovo, Maximiano Ferreira; Faraco Junior, Italo Medeiros

    2014-01-01

    Objective This study aimed at describing the profiles of Brazilian and international studies published in orthodontic journals. Methods The sample comprised 635 articles selected from two scientific journals, i.e., Dental Press Journal of Orthodontics and American Journal of Orthodontics and Dentofacial Orthopedics, which were analyzed at three different intervals over a 10-year period (1999 - 2004 - 2009). Articles were described in terms of knowledge domain, study design, and country of origin (or state of origin for Brazilian papers). Results The most frequent study designs adopted in international studies were cohort (23.9%) and cross-sectional (21.7%) designs. Among Brazilian papers, cross-sectional studies (28.9%) and literature reviews (24.6%) showed greater frequency. The topics most often investigated were dental materials (17%) and treatment devices (12.4%) in international articles, with the latter topic being addressed by 16% of the Brazilian publications, followed by malocclusion, with 12.6%. In all cases, the most frequent countries of origin coincided with the countries of origin of each journal. Conclusions The majority of the studies analyzed featured a low level of scientific evidence. Moreover, the findings showed that journals tend to publish studies produced in their own country of origin, and that there are marked discrepancies in the number of papers published by different Brazilian states. PMID:24945515

  11. No Outbreak of Vancomycin and Linezolid Resistance in Staphylococcal Pneumonia over a 10-Year Period

    PubMed Central

    Yayan, Josef; Ghebremedhin, Beniam; Rasche, Kurt

    2015-01-01

    Background Staphylococci can cause wound infections and community- and nosocomial-acquired pneumonia, among a range of illnesses. Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) have been rapidly increasing as a cause of infections worldwide in recent decades. Numerous reports indicate that S. aureus and MRSA are becoming resistant to many antibiotics, which makes them very dangerous. Therefore, this study retrospectively investigated the resistance to antimicrobial agents in all hospitalized patients suffering from community- or nosocomial-acquired pneumonia due to S. aureus and MRSA. Methods Information from the study groups suffering from either community- or nosocomial-acquired pneumonia caused by S. aureus or MRSA was gathered by searching records from 2004 to 2014 at the HELIOS Clinic Wuppertal, Witten/Herdecke University, Germany. The findings of antibiotic resistance were analyzed after the evaluation of susceptibility testing for S. aureus and MRSA. Results Total of 147 patients (63.9%, 95% CI 57.5%–69.8%), mean age 67.9 ± 18.5 years, with pneumonia triggered by S. aureus, and 83 patients (36.1%, 95% CI 30.2%–42.5%), mean age 72.3 ± 13.8 years, with pneumonia due to MRSA. S. aureus and MRSA developed no resistance to vancomycin (P = 0.019 vs. < 0.0001, respectively) or linezolid (P = 0.342 vs. < 0.0001, respectively). MRSA (95.3%) and S. aureus (56.3%) showed a high resistance to penicillin. MRSA (87.7%) was also found to have a high antibiotic resistance against ß-lactam antibiotics, compared to S. aureus (9.6%). Furthermore, MRSA compared to S. aureus, respectively, had increased antibiotic resistance to ciprofloxacin (90.1% vs. 17.0%), cefazolin (89.7% vs. 10.2%), cefuroxime (89.0% vs. 9.1%), levofloxacin (88.2% vs. 18.4%), clindamycin (78.0% vs. 14.7%), and erythromycin (76.5% vs. 20.8%). Conclusion No development of resistance was found to vancomycin and linezolid in patients with pneumonia caused by S. aureus and MRSA. PMID

  12. Use of Qualitative Methods in Published Health Services and Management Research: A 10-Year Review

    PubMed Central

    Weiner, Bryan J.; Amick, Halle R.; Lund, Jennifer L.; Lee, Shoou-Yih Daniel; Hoff, Timothy J.

    2011-01-01

    Over the past 10 years, the field of health services and management research has seen renewed interest in the use of qualitative research methods. This article examines the volume and characteristics of qualitative research articles published in nine major health services and management journals between 1998 and 2008. Qualitative research articles comprise 9% of research articles published in these journals. Although the publication rate of qualitative research articles has not kept pace with that of quantitative research articles, citation analysis suggests that qualitative research articles contribute comparably to the field’s knowledge base. A wide range of policy and management topics has been examined using qualitative methods. Case study designs, interviews, and documentary sources were the most frequently used methods. Half of qualitative research articles provided little or no detail about key aspects the study’s methods. Implications are discussed and recommendations are offered for promoting the publication of qualitative research. PMID:20675353

  13. Use of qualitative methods in published health services and management research: a 10-year review.

    PubMed

    Weiner, Bryan J; Amick, Halle R; Lund, Jennifer L; Lee, Shoou-Yih Daniel; Hoff, Timothy J

    2011-02-01

    Over the past 10 years, the field of health services and management research has seen renewed interest in the use of qualitative research methods. This article examines the volume and characteristics of qualitative research articles published in nine major health services and management journals between 1998 and 2008. Qualitative research articles comprise 9% of research articles published in these journals. Although the publication rate of qualitative research articles has not kept pace with that of quantitative research articles, citation analysis suggests that qualitative research articles contribute comparably to the field's knowledge base. A wide range of policy and management topics has been examined using qualitative methods. Case study designs, interviews, and documentary sources were the most frequently used methods. Half of qualitative research articles provided little or no detail about key aspects the study's methods. Implications are discussed and recommendations are offered for promoting the publication of qualitative research.

  14. From methadone to buprenorphine: changes during a 10 year period within a national opioid maintenance treatment programme.

    PubMed

    Riksheim, Marianne; Gossop, Michael; Clausen, Thomas

    2014-03-01

    Opioid maintenance treatment (OMT) is the most widely used treatment for opioid dependence. Maintenance programmes differ in various aspects and may also change over time. This paper investigates the changes in treatment practices within a national OMT programme during a 10 year period (2002-2011), especially with regard to the prescribing of methadone and buprenorphine. Data (n=34,001) were collected by annual assessments questionnaires. In 2002, only 16% of the OMT patients received buprenorphine as their maintenance medication. By 2011 this percentage had increased significantly (p<.001) to 50.3%. In the same period the number of patients more than tripled (from 1,984 to 6,640, p<.001), and programme attrition rates decreased (p=.020). This relatively rapid shift is a part of the increasing reliance of addiction medicine upon a range of medications administered by different routes which has not been previously charted within a national treatment programme.

  15. Changes in Active Commuting to School in Czech Adolescents in Different Types of Built Environment across a 10-Year Period

    PubMed Central

    Dygrýn, Jan; Mitáš, Josef; Gába, Aleš; Rubín, Lukáš; Frömel, Karel

    2015-01-01

    Active commuting (AC) to school represents a great opportunity to incorporate walking or cycling into adolescents’ everyday routine. The objective of the study was to describe changes in AC in Czech adolescents across a 10-year period in different built environments. Data from the 2001 and 2011 Czech Census of Population and Housing were used to examine the mode of transportation taken to school in 6236 adolescents. Changes in AC over time were analyzed for low and high walkable areas separately in two Czech regional cities, Olomouc and Hradec Králové. Between 2001 and 2011, the proportion of adolescents actively commuting to school decreased by 47%, from an absolute rate of 49.1% to 26%. The proportion of active commuters fell in low walkable areas by 61% and in high walkable areas by 39%. The results indicated that adolescents in 2011 were 2.7 times less (OR = 0.365, p < 0.001) likely to actively commute than in 2001. The AC behavior in Czech adolescents has a negative tendency to replicate travel-to-school patterns in adolescents previously described in more developed countries. The findings might serve as a recommendation for municipal policy. PMID:26501304

  16. Herpes Simplex Encephalitis (HSE) and its outcome in the Patients who were Admitted to a Tertiary Care Hospital in Mashhad, Iran, over a 10-year Period

    PubMed Central

    Sheybani, F.; Arabikhan, H.R.; Naderi, H.R.

    2013-01-01

    Introduction: The effective cure rate of acyclovir emphasizes the importance of an early diagnosis and treatment in reducing the considerable mortality and the morbidity in patients with Herpes Simplex Encephalitis (HSE). Methods: The demographic as well as clinical features, the lab data and the neuroimaging findings of the patients with HSE, which were confirmed by Cerebrospinal Fluid (CSF) PCR and/or brain MRI, were reviewed and analyzed statistically over a 10-year period. Results: Over a 10-year period, the characteristics of 45 patients with HSE were reviewed. 34 (76%) out of the 45 patients showed positive CSF HSV-1 PCR results. 8 (18%) had a normal CSF analysis and a CSF/blood glucose ratio of less than 0.5 was observed in 13 (29%) patients, while 14% had PMN-dominant pleocytosis. 68% of the patients for whom brain MRI was performed, had temporal lobe involvement. While 37 (83%) patients recovered completely, 6 (13%) survived with sequelae, and 2 (4%) died. Conclusion: Because of the increasing number of atypical forms of HSE and the great impact of an early diagnosis and treatment on a favourable outcome, the acyclovir therapy should be administrated for any type of febrile encephalopathy of unknown aetiology, until HSE can be excluded. PMID:24086858

  17. Causes of death in Japanese diabetics: A questionnaire survey of 18,385 diabetics over a 10-year period.

    PubMed

    Hotta, Nigishi; Nakamura, Jiro; Iwamoto, Yasuhiko; Ohno, Yoshiyuki; Kasuga, Masato; Kikkawa, Ryuichi; Toyota, Takayoshi

    2010-04-22

    We collated and analysed data from hospital records regarding the cause of death of 18,385 patients with diabetes who died in 282 medical institutions throughout Japan over the 10-year period between 1991 and 2000. Autopsy was carried out in 1750 cases. The most frequent cause of death in all 18,385 cases was malignant neoplasia, accounting for 34.1% of cases, followed by vascular diseases (including diabetic nephropathy, ischemic heart diseases and cerebrovascular diseases) in 26.8%, infections in 14.3%, and then diabetic coma in 1.2%. The most common malignancy was liver cancer, accounting for 8.6% of all the deaths. Of the deaths from vascular diseases, diabetic nephropathy was the cause of death in 6.8% of cases, and the frequency as cause of death for ischemic heart diseases and cerebrovascular diseases were similar at 10.2% and 9.8%, respectively. Myocardial infarction accounted for almost all the deaths from ischemic heart diseases, whereas deaths from cerebral infarction were 2.2-fold as common as those from cerebral hemorrhage. In the analyses of the relationship between age and causes of death in diabetic patients who underwent autopsy, the overall mortality rate as a result of vascular diseases increased with age, although the mortality rates from diabetic nephropathy and cerebrovascular diseases increased little from the fifth decade of life. The mortality rate from ischemic heart diseases increased with age, however, and was higher than the other forms of vascular diseases from the sixth decade of life, accounting for approximately 50% of vascular deaths in the eighth decade. Malignant neoplasia was the most frequent cause of death from the fifth decade of life, and was extremely common in the seventh decade, accounting for 46.3% of all the deaths. The mortality rate from infections varied little between age groups from the fifth decade of life. In the analyses of glycemic control and the age at the time of death, lifespans were 2.5 years shorter in

  18. Changes in the types of liver diseases requiring hepatic resection: a single-institution experience of 9016 cases over a 10-year period

    PubMed Central

    Cho, Hwui-Dong; Lee, Young-Joo; Park, Kwang-Min; Kim, Ki-Hun; Kim, Jin Cheon; Ahn, Chul-Soo; Moon, Deok-Bog; Ha, Tae-Yong; Lee, Sung-Gyu

    2016-01-01

    Backgrounds/Aims To understand the changing demands for hepatic resection (HR), we collected data regarding HR performed in a tertiary centre over a period of 10 years. Methods We carried out extensive search of institutional databases to identify HR cases performed between January 2005 and December 2014. A study cohort of 9,016 patients were divided into 5 disease categories, namely hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), intrahepatic duct stone disease (IHDS), colorectal cancer liver metastasis (CRLM), and uncommon/rare diseases (URD). Results There were 5,661 (62.8%) HCC cases, followed by 1441 (16.0%) CRLM, 942 (10.5%) ICC, 638 (7.1%) IHDS and 334 (3.7%) URD. The number of annual HR cases gradually increased from 443 in 2005 to 1,260 in 2015. Annual HCC cases also gradually increased, but the annual proportion of HCC cases fluctuated narrowly between 58.3% and 70.2%. Annual CRLM cases increased rapidly, and their proportion increased progressively from 4.7% to 20.5%. Annual ICC cases increased slowly, and their annual proportion fluctuated between 7.2% and 15.6%. Annual IHDS cases decreased slowly, and their annual proportion decreased progressively from 17.2% to 3.4%, while annual URD cases fluctuated, with annual proportions varying between 2.3% and 5.6%. Conclusions Annual cases of HR increased over the last 10 years in a tertiary center probably due to a center-specific centralization effect. The number of CRLM cases increased rapidly; those of HCC and ICC increased gradually, and those of IHDS declined gradually. We believe that these results reflect real changes in the types of liver disease requiring HR. PMID:27212990

  19. Processes of physical change to the seabed and bivalve recruitment over a 10-year period following experimental hydraulic clam dredging on Banquereau, Scotian Shelf

    NASA Astrophysics Data System (ADS)

    Gilkinson, K.; King, E. L.; Li, M. Z.; Roddick, D.; Kenchington, E.; Han, G.

    2015-01-01

    A previous study on the effects of experimental hydraulic clam dredging on seabed habitat and commercial bivalve populations revealed a lack of recovery after a 3-year post-dredging period (1998-2001) on a deep (65-75 m) offshore sandy bank on the Scotian Shelf, Canada. Follow-up sidescan sonar surveys were carried out 5 and 10 years after dredging (2003, 2008) in order to identify long-term processes of seabed recovery. Grab sampling was carried out 10 years after dredging to identify post-dredging commercial bivalve recruitment. Changes in the seafloor, including dredge tracks, were documented with a series of 7 sidescan sonar surveys between 1998 and 2008. A sediment mobility model was constructed based on modeled tidal current and hindcast wave data over this time period to quantify natural seabed disturbance and interpret changes to the dredge tracks mapped by sidescan sonar surveys. The model indicated that tidal currents had minimal effect on sediment mobilization. The main driving force associated with re-working of surficial sediments as evidenced by deterioration of dredge tracks in sonograms was annual fall/winter storms. While the annual frequency of storms and associated wave heights was variable, the observations and sediment mobility calculations suggest that the most influential variable is the magnitude of individual large storms, specifically storms with a significant wave height of ∼11 m. These storms are capable of generating mobile sediment layers of 20-30 cm thickness, equivalent to the dredge blade cutting depth. It appears that, with minor exceptions, sediment properties have returned to pre-dredging conditions 10 years after dredging in this habitat. Based on known age-length relationships, the four commercial bivalve species showed very low recruitment at the experimental site over the 10-year post-dredging period. However, this is unlikely due to a dredging effect since a similar pattern was observed in non-dredged areas.

  20. A bibliometric analysis of toxicology research productivity in Middle Eastern Arab countries during a 10-year period (2003–2012)

    PubMed Central

    2014-01-01

    Background Bibliometric studies are increasingly being used for research assessment by involving the application of statistical methods to scientific publications to obtain the bibliographics for each country. The main objective of this study was to analyse the research productivity originating from 13 Middle Eastern Arab (MEA) countries with articles published in toxicology journals. Methods Data from January 1, 2003 till December 31, 2012 were searched for documents with specific words in the toxicology field as a “source title” in any one of the 13 MEA countries. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies. Research productivity was adjusted to the national population and nominal gross domestic product (GDP) per capita. Results Documents (n = 1,240) were retrieved from 73 international peer-reviewed toxicology journals. The h-index of the retrieved documents was 39. Of the 73 journal titles, 52 (69.9%) have their IF listed in the ISI Journal Citation Reports 2012; 198 documents (16.0%) were published in journals that had no official IF. After adjusting for economy and population power, Egypt (193.6), Palestine (18.1), Kingdom of Saudi Arabia (KSA) (13.0), and Jordan (11.5) had the highest research productivity. Countries with large economies, such as the Kuwait, United Arab Emirates (UAE), and Oman, tended to rank relatively low after adjustment of GDP. The total number of citations at the time of data analysis (August 4, 2013) was 10,991, with a median (interquartile range) of 4 (1–11). MEA collaborated more with countries in the MEA regions (16.7%), especially KSA, Egypt, and UAE, followed by Europe (14.4%), especially with the United Kingdom and Germany. Conclusions The present data show a promising rise and a good start for toxicology research activity in toxicology journals in the Arab world. Research output is low in some countries, which can be improved by investing in more

  1. Antibiotic Resistance of Pseudomonas aeruginosa in Pneumonia at a Single University Hospital Center in Germany over a 10-Year Period

    PubMed Central

    Yayan, Josef; Ghebremedhin, Beniam; Rasche, Kurt

    2015-01-01

    Background Pseudomonas aeruginosa is a common cause of community-acquired and nosocomial-acquired pneumonia. The development of resistance of P. aeruginosa to antibiotics is increasing globally due to the overuse of antibiotics. This article examines, retrospectively, the antibiotic resistance in patients with community-acquired versus nosocomial-acquired pneumonia caused by P. aeruginosa or multidrug-resistant (MDR) P. aeruginosa. Methods Data from patients with community-acquired and nosocomial-acquired pneumonia caused by P. aeruginosa and MDR P. aeruginosa were collected from the hospital charts at the HELIOS Clinic, Witten/Herdecke University, Wuppertal, Germany, between January 2004 and August 2014. An antibiogram was created from all study patients with community-acquired and nosocomial-acquired pneumonia caused by P. aeruginosa or MDR P. aeruginosa. Results A total of 168 patients with mean age 68.1 ± 12.8 (113 [67.3% males and 55 [32.7%] females) were identified; 91 (54.2%) had community-acquired and 77 (45.8%) had nosocomial-acquired pneumonia caused by P. aeruginosa. Patients with community-acquired versus nosocomial-acquired pneumonia had a mean age of 66.4 ± 13.8 vs. 70.1 ± 11.4 years [59 vs. 54 (64.8% vs. 70.1%) males and 32 vs. 23 (35.2% vs. 29.9%) females]. They included 41 (24.4%) patients with pneumonia due to MDR P. aeruginosa: 27 (65.9%) community-acquired and 14 (34.1%) nosocomial-acquired cases. P. aeruginosa and MDR P. aeruginosa showed a very high resistance to fosfomycin (community-acquired vs. nosocomial-acquired) (81.0% vs. 84.2%; 0 vs. 85.7%). A similar resistance pattern was seen with ciprofloxacin (35.2% vs. 24.0%; 70.4% vs. 61.5%), levofloxacin (34.6% vs. 24.5%; 66.7% vs. 64.3%), ceftazidime (15.9% vs. 30.9; 33.3% vs. 61.5%), piperacillin (24.2% vs. 29.9%; 44.4% vs. 57.1%), imipenem (28.6% vs. 27.3%; 55.6% vs. 50.0%), piperacillin and tazobactam (23.1% vs. 28.6%; 44.4% vs. 50.0%), tobramycin (28.0% vs. 17.2%; 52.0% vs. 27

  2. Decline in lymphatic filariasis transmission with annual mass drug administration using DEC with and without albendazole over a 10year period in India.

    PubMed

    Sunish, I P; Kalimuthu, M; Rajendran, R; Munirathinam, A; Ashok Kumar, V; Nagaraj, J; Tyagi, B K

    2015-02-01

    The National Programme for the Elimination of Lymphatic Filariasis is underway in the endemic districts of Tamil Nadu State, South India, since 2001. Annual mass drug administration (MDA) was carried out by the state health department to all eligible individuals. The impact of MDAs on transmission parameters was evaluated in 2 revenue blocks, viz, one with DEC alone and the other with a combination of albendazole. After 10 years with 6 annual MDAs, the transmission indices reached low levels in both treatment arms, but still persisted. However, the DEC alone arm showed higher transmission rates, compared to the DEC+ALB arm. Few villages which demonstrated persistent transmission need to be targeted with an additional control measure viz, vector control, to achieve LF elimination. It is evident from the 10 year period of the study that inclusion of albendazole along with DEC has significantly reduced the transmission indices to almost nil level, as compared to DEC alone.

  3. 10-year prevalence of contact allergy in the general population in Denmark estimated through the CE-DUR method.

    PubMed

    Thyssen, Jacob Pontoppidan; Uter, Wolfgang; Schnuch, Axel; Linneberg, Allan; Johansen, Jeanne Duus

    2007-10-01

    The prevalence of contact allergy in the general population has traditionally been investigated through population-based epidemiological studies. A different approach is the combination of clinical epidemiological (CE) data and the World Health Organization-defined drug utilization research (DUR) method. The CE-DUR method was applied in Denmark to estimate the prevalence of contact allergy in the general population and compare it with the prevalence estimates from the Glostrup allergy studies. Contact allergy prevalence estimates ranging from very liberal ('worst case') to conservative ('best case') assumptions were based on patch test reading data in combination with an estimate of the number of persons eligible for patch testing each year based on sales data of the 'standard series'. The estimated 10-year prevalence of contact allergy ranged between 7.3% and 12.9% for adult Danes older than 18 years. The 10-year prevalence of contact allergy measured by CE-DUR was slightly lower than previous prevalence estimates from the Glostrup allergy studies. This could probably be explained by a decrease in nickel allergy. The CE-DUR approach holds the potential of being an efficient and easy monitoring method of contact allergy prevalence.

  4. Reducing Prescriptions of Long-Acting Benzodiazepine Drugs in Denmark: A Descriptive Analysis of Nationwide Prescriptions during a 10-Year Period.

    PubMed

    Eriksen, Sophie Isabel; Bjerrum, Lars

    2015-06-01

    Prolonged consumption of benzodiazepine drugs (BZD) and benzodiazepine receptor agonists (zolpidem, zaleplon, zopiclone; altogether Z drugs) is related to potential physiological and psychological dependence along with other adverse effects. This study aimed to analyse the prescribing of long-acting BZD (half-life >10 hr), compared to short-acting BZD in Denmark during a 10-year period. Descriptive analysis of total sales data from the Danish Register of Medicinal Product Statistics, to individuals in the primary healthcare sector, of all BZD and Z drugs in the period of 2003-2013. Prescription data derive from all community and hospital pharmacies in Denmark. The prescribing of long-acting BZD was reduced from 25.8 defined daily doses (DDD)/1000 inhabitants/day in 2003 to 8.8 DDD/1000 inhabitants/day in 2013, a relative reduction of 66%. The prescribing of short-acting BZD was reduced from 26.1 DDD/1000 inhabitants/day in 2003 to 16.4 DDD/1000 inhabitants/day in 2013, a relative reduction of 37%. Prescription data in this study did not include information about indications for initiating treatments. In addition, due to compliance problems, some of the prescribed drugs may not have been consumed according to the prescription. The observed reduction in BZD use was correlated to the introduction of new national guidelines on prescription of addictive drugs, but this study was not designed to detect a causal relationship. The prescribing of long-acting BZD decreased considerably more than the prescribing of short-acting BZD in the 10-year period. PMID:25382355

  5. The Vaginal Microbiota over an 8- to 10-Year Period in a Cohort of HIV-Infected and HIV-Uninfected Women

    PubMed Central

    Mehta, Supriya D.; Donovan, Brock; Weber, Kathleen M.; Cohen, Mardge; Ravel, Jacques; Gajer, Pawel; Gilbert, Douglas; Burgad, Derick; Spear, Greg T.

    2015-01-01

    Background We identified predominant vaginal microbiota communities, changes over time, and how this varied by HIV status and other factors in a cohort of 64 women. Methods Bacterial DNA was extracted from reposited cervicovaginal lavage samples collected annually over an 8–10 year period from Chicago Women’s Interagency HIV Study participants: 22 HIV-negative, 22 HIV-positive with stable infection, 20 HIV-positive with progressive infection. The vaginal microbiota was defined by pyrosequencing of the V1/V2 region of the 16S rRNA gene. Scheduled visits included Bacterial vaginsosis (BV) screening; clinically detected cases were referred for treatment. Hierarchical clustering identified bacterial community state types (CST). Multinomial mixed effects modeling determined trends over time in CST, by HIV status and other factors. Results The median follow-up time was 8.1 years (range 5.5–15.3). Six CSTs were identified. The mean relative abundance (RA) of Lactobacillus spp. by CST (with median number of bacterial taxa) was: CST-1–25.7% (10), CST-2–27.1% (11), CST-3–34.6% (9), CST-4–46.8% (9), CST-5–57.9% (4), CST-6–69.4% (2). The two CSTs representing the highest RA of Lactobacillus and lowest diversity increased with each additional year of follow-up (CST-5, adjusted odds ratio (aOR) = 1.62 [95% CI: 1.34–1.94]; CST-6, aOR = 1.57 [95 CI: 1.31–1.89]), while the two CSTs representing lowest RA of Lactobacillus and higher diversity decreased with each additional year (CST-1, aOR = 0.89 [95% CI: 0.80–1.00]; CST-2, aOR = 0.86 [95% CI: 0.75–0.99]). There was no association between HIV status and CST at baseline or over time. CSTs representing lower RA of Lactobacillus were associated with current cigarette smoking. Conclusions The vaginal microbial community significantly improved over time in this cohort of women with HIV and at high risk for HIV who had regular detection and treatment referral for BV. PMID:25675346

  6. Evidence of a dominant lineage of Vibrio cholerae-specific lytic bacteriophages shed by cholera patients over a 10-year period in Dhaka, Bangladesh.

    PubMed

    Seed, Kimberley D; Bodi, Kip L; Kropinski, Andrew M; Ackermann, Hans-Wolfgang; Calderwood, Stephen B; Qadri, Firdausi; Camilli, Andrew

    2011-01-01

    Lytic bacteriophages are hypothesized to contribute to the seasonality and duration of cholera epidemics in Bangladesh. However, the bacteriophages contributing to this phenomenon have yet to be characterized at a molecular genetic level. In this study, we isolated and sequenced the genomes of 15 bacteriophages from stool samples from cholera patients spanning a 10-year surveillance period in Dhaka, Bangladesh. Our results indicate that a single novel bacteriophage type, designated ICP1 (for the International Centre for Diarrhoeal Disease Research, Bangladesh cholera phage 1) is present in all stool samples from cholera patients, while two other bacteriophage types, one novel (ICP2) and one T7-like (ICP3), are transient. ICP1 is a member of the Myoviridae family and has a 126-kilobase genome comprising 230 open reading frames. Comparative sequence analysis of ICP1 and related isolates from this time period indicates a high level of genetic conservation. The ubiquitous presence of ICP1 in cholera patients and the finding that the O1 antigen of lipopolysaccharide (LPS) serves as the ICP1 receptor suggest that ICP1 is extremely well adapted to predation of human-pathogenic V. cholerae O1.

  7. What Are the Trends in Tonsillectomy Techniques in Wales? A Prospective Observational Study of 19,195 Tonsillectomies over a 10-Year Period

    PubMed Central

    Walijee, Hussein; Al-Hussaini, Ali; Harris, Andrew; Owens, David

    2015-01-01

    There are a multitude of techniques to undertake tonsillectomy, with hot techniques such as diathermy and coblation being associated with a higher risk of secondary haemorrhage. The UK National Prospective Tonsillectomy Audit (2004) advocated cold steel dissection and ties to be the gold standard. This prospective observational study investigates the trends in tonsillectomy techniques across Wales in the last decade to establish if surgeons have adhered to this national guidance. Data relating to tonsillectomy were extracted over a 10-year period from 1 January 2003 to 31 December 2012 from the Wales Surgical Instrument Surveillance Programme database. A total of 19,195 patients were included. Time-series analysis using linear regression showed there was an increase in the number of bipolar diathermy tonsillectomies by 84% (Pearson's r = 0.762, p = 0.010) and coblation tonsillectomies by 120% (r = 0.825, p = 0.003). In contrast, there was a fall in the number of cold steel dissection tonsillectomies with ties by 60% (r = −0.939, p < 0.001). This observational study suggests that the use of bipolar and coblation techniques for tonsillectomy has increased. This deviation from national guidance may be due to these techniques being faster with less intraoperative bleeding. Further study for the underlying reasons for the increase in these techniques is warranted. PMID:26693228

  8. What Are the Trends in Tonsillectomy Techniques in Wales? A Prospective Observational Study of 19,195 Tonsillectomies over a 10-Year Period.

    PubMed

    Walijee, Hussein; Al-Hussaini, Ali; Harris, Andrew; Owens, David

    2015-01-01

    There are a multitude of techniques to undertake tonsillectomy, with hot techniques such as diathermy and coblation being associated with a higher risk of secondary haemorrhage. The UK National Prospective Tonsillectomy Audit (2004) advocated cold steel dissection and ties to be the gold standard. This prospective observational study investigates the trends in tonsillectomy techniques across Wales in the last decade to establish if surgeons have adhered to this national guidance. Data relating to tonsillectomy were extracted over a 10-year period from 1 January 2003 to 31 December 2012 from the Wales Surgical Instrument Surveillance Programme database. A total of 19,195 patients were included. Time-series analysis using linear regression showed there was an increase in the number of bipolar diathermy tonsillectomies by 84% (Pearson's r = 0.762, p = 0.010) and coblation tonsillectomies by 120% (r = 0.825, p = 0.003). In contrast, there was a fall in the number of cold steel dissection tonsillectomies with ties by 60% (r = -0.939, p < 0.001). This observational study suggests that the use of bipolar and coblation techniques for tonsillectomy has increased. This deviation from national guidance may be due to these techniques being faster with less intraoperative bleeding. Further study for the underlying reasons for the increase in these techniques is warranted.

  9. What Are the Trends in Tonsillectomy Techniques in Wales? A Prospective Observational Study of 19,195 Tonsillectomies over a 10-Year Period.

    PubMed

    Walijee, Hussein; Al-Hussaini, Ali; Harris, Andrew; Owens, David

    2015-01-01

    There are a multitude of techniques to undertake tonsillectomy, with hot techniques such as diathermy and coblation being associated with a higher risk of secondary haemorrhage. The UK National Prospective Tonsillectomy Audit (2004) advocated cold steel dissection and ties to be the gold standard. This prospective observational study investigates the trends in tonsillectomy techniques across Wales in the last decade to establish if surgeons have adhered to this national guidance. Data relating to tonsillectomy were extracted over a 10-year period from 1 January 2003 to 31 December 2012 from the Wales Surgical Instrument Surveillance Programme database. A total of 19,195 patients were included. Time-series analysis using linear regression showed there was an increase in the number of bipolar diathermy tonsillectomies by 84% (Pearson's r = 0.762, p = 0.010) and coblation tonsillectomies by 120% (r = 0.825, p = 0.003). In contrast, there was a fall in the number of cold steel dissection tonsillectomies with ties by 60% (r = -0.939, p < 0.001). This observational study suggests that the use of bipolar and coblation techniques for tonsillectomy has increased. This deviation from national guidance may be due to these techniques being faster with less intraoperative bleeding. Further study for the underlying reasons for the increase in these techniques is warranted. PMID:26693228

  10. Formulation of an organic carbon trajectory over a 10-year period on a restored spoil island in south-central Florida

    NASA Astrophysics Data System (ADS)

    Schafer, T.; Ellis, R.; Osborne, T.; Hicks Pries, C.

    2015-12-01

    Long-term monitoring of restoration projects aims to determine long-term sustainability and stability of restored systems. In coastal wetlands, one indicator of restoration of ecosystem function can be seen with organic matter (specifically carbon) accretion. SL-15, a spoil island in Fort Pierce, Fl was restored in 2005, and has been monitored for return to natural condition over the last 10 years.. To assess sediment carbon accretion, sediment cores were collected in a set of eight plots, located on the SL-15 mangrove island and the surrounding seagrass recruitment area. These were analyzed for organic carbon, microbial biomass carbon, extractable carbon, and total nitrogen. The biogeochemical data collected in the previous year was compared to data collected in 2005-2007. Vegetation surveys were also completed to show the build-up of organic material in accordance with vegetation shift over the 9-year period. From this information, a trajectory has been formulated on organic carbon accretion and vegetation shift from the time of orginal restoration activities. By comparison to control sites nearby, realistic estimates of time required to reach natural levels of carbon and vegetation community structure can be calculated..

  11. 10-Year Research Update Review: The Epidemiology of Child and Adolescent Psychiatric Disorders--I. Methods and Public Health Burden

    ERIC Educational Resources Information Center

    Costello, E. Jane; Egger, Helen; Angold, Adrian

    2005-01-01

    Objective: To review recent progress in child and adolescent psychiatric epidemiology in the area of prevalence and burden. Method: The literature published in the past decade was reviewed under two headings: methods and findings. Results: Methods for assessing the prevalence and community burden of child and adolescent psychiatric disorders have…

  12. Is it time to bring the “Parent” into the prevention of parent to child transmission programs in India? A study of trends over a 10-year period in a prevention of parent to child transmission clinic in India

    PubMed Central

    Shiradkar, Swati; Mande, Shubhangi; Bapat, Gauri; Setia, Maninder Singh

    2016-01-01

    Objectives: The present study evaluated the changes in serology and human immunodeficiency virus (HIV) testing behaviors over a 10-year period in a center in India. Methods: We used clinical data collected at the antenatal clinic from 2002 to 2011. The key outcomes were: (1) Proportion of women who opted for HIV test and those who tested positive; (2) proportion of male partners who came in for HIV test and those who tested positive; and (3) proportion of women who opted for continuation of pregnancy or for medical termination of pregnancy. Results: We tested 11,452 women for HIV over the 10-year period from 2002 to 2011. The proportion of women who opted for HIV testing was 72.0% (95% confidence interval [CI]: 70.7–73.4%). The acceptance of test increased from 35.9% (95% CI: 31.7–40.4%) in 2002 to the peak of 82.6% (95% CI: 78.6–86.8%) in 2009 (P < 0.001). The overall HIV prevalence over the decade was 0.70% (95% CI: 0.55–0.87%). The prevalence high at 1.11% (95% CI: 0.23–3.24%) in 2002 and reduced to 0.37% (95% CI: 0.12–0.87%) in 2011 (P < 0.001). Only 0.57% of male partners tested for HIV over this time period. Conclusion: Strategies to improve acceptance of testing in pregnant women should be included in the Indian guidelines. The male partners do not get tested. Thus, this component needs to be strengthened - by targeted interventions for male spouses - to make the program more effective. PMID:27190414

  13. Evaluation of survival and success rates of dental implants reported in longitudinal studies with a follow-up period of at least 10 years: a systematic review.

    PubMed

    Moraschini, V; Poubel, L A da C; Ferreira, V F; Barboza, E dos S P

    2015-03-01

    The aim of this systematic review was to evaluate the survival and success rates of osseointegrated implants determined in longitudinal studies that conducted a follow-up of at least 10 years. A broad electronic search was conducted in MEDLINE/PubMed and the Cochrane Central Register of Controlled Trials (CENTRAL) for relevant publications in indexed journals, evaluating the clinical performance of dental implants. Using inclusion and exclusion criteria, two reviewers analyzed titles, abstracts, and complete articles, prioritizing studies of the randomized clinical trial type. A total of 23 articles were included in this review. Ten prospective studies, nine retrospective studies, and four randomized clinical trials, which evaluated 7711 implants, were selected. The mean follow-up time of the studies included was 13.4 years. All of the studies reported survival rates and mean marginal bone resorption values, with cumulative mean values of 94.6% and 1.3mm, respectively. Fourteen studies related success rates. Taking into consideration the disparate outcome measures employed to assess dental implant performance and within the limitations of this systematic review, we may affirm that osseointegrated implants are safe and present high survival rates and minimal marginal bone resorption in the long term.

  14. [Homicide in the elderly. A study of homicide in the aged based on an Aachen autopsy sample of the 10-year period 1976-1985].

    PubMed

    Schäfer, A T

    1989-01-01

    Investigations on the peculiarities of homicides of the elderly are missing in the German literature up to the present date. Therefore we undertook an evaluation of the case files collected at the Aachen Institute of Forensic Medicine from the ten-year-period 1976-1985. Among 3736 autopsies we found 183 cases of homicide with 35 victims of 60 years and older. We collected peculiarities of modus operandi related to victim, suspect and offence and compared the data with such from police criminal statistics and partially with German population statistics. Two types of homicide of the elderly can be differentiated: One is independent of the victim's age whereas the other exploits the living conditions in the higher age (living alone, socially isolated, ailing, helpless etc.) For these latter cases the name "Gerontocide" is proposed. The paper deals with the peculiar difficulties of criminal investigation and clarification in such cases, resulting on the one hand from the lack of suspicion if elderly people die, on the other hand from the more difficult detection of causal relationship between offence and death--especially in the presence of severe illness of the victim.

  15. Development of venous thromboembolism (VTE) in patients undergoing surgery for brain tumors: results from a single center over a 10 year period.

    PubMed

    Smith, Timothy R; Nanney, Allan D; Lall, Rishi R; Graham, Randall B; McClendon, Jamal; Lall, Rohan R; Adel, Joseph G; Zakarija, Anaadriana; Cote, David J; Chandler, James P

    2015-03-01

    Patients who undergo craniotomy for brain neoplasms have a high risk of developing venous thromboembolism (VTE), including deep vein thromboses (DVT) and pulmonary emboli (PE). The reasons for this correlation are not fully understood. This retrospective, single-center review aimed to determine the risk factors for VTE in patients who underwent neurosurgical resection of brain tumors at Northwestern University from 1999 to 2010. Our cohort included 1148 patients, 158 (13.7%) of whom were diagnosed with DVT and 38 (3.3%) of whom were diagnosed with PE. A variety of clinical factors were studied to determine predictors of VTE, including sex, ethnicity, medical co-morbidities, surgical positioning, length of hospital stay, tumor location, and tumor histology. Use of post-operative anticoagulants and hemorrhagic complications were also investigated. A prior history of VTE was found to be highly predictive of post-operative DVT (odds ratio [OR]=7.6, p=0.01), as was the patient's sex (OR=14.2, p<0.001), ethnicity (OR=0.5, p=0.04), post-operative intensive care unit days (OR=0.2, p=0.003), and tumor histology (OR=-0.16, p=0.01). Contrary to reports in the literature, the data collected did not indicate that the administration of post-operative medical prophylaxis for VTE was significant in preventing their formation (OR=-0.14, p=0.76). Hemorrhagic complications were low (2.2%) and resultant neurologic deficit was lower still (0.7%). The study indicates that patients with high-grade primary brain tumors and metastatic lesions should receive aggressive preventative measures in the post-operative period.

  16. Changes in serum levels of perfluoroalkyl substances during a 10-year follow-up period in a large population-based cohort.

    PubMed

    Stubleski, Jordan; Salihovic, Samira; Lind, Lars; Lind, P Monica; van Bavel, Bert; Kärrman, Anna

    2016-10-01

    Poly- and perfluoroalkyl substances (PFASs) are a group of man-made fluorinated chemicals which have, at background levels, been associated with negative health effects in humans. Thus far, most human biomonitoring studies have evaluated the general change in PFAS concentration over time by continuously testing various individuals. This is one of the few studies to report the longitudinal trend of a range of PFAS concentrations in humans. In addition, this is the first known longitudinal study to include a large background level exposed cohort of both men and women with the same age and location who were repeatedly sampled from 2001 to 2014. The longitudinal change in concentration of eight PFASs detected in serum collected from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort were determined and compared to results from general population studies. The sex-dependent changes in PFAS concentrations over time were also assessed. Serum was sampled from the same individuals at ages 70 (collection period 2001-2004), 75 (2006-2009) and 80 (2011-2014,). Eight (C6-11) of fourteen (C4-13) analyzed PFASs were usually detected in over 75% of individuals and assessed using a random effects (mixed) model. In the 579 individuals attending all three examinations, PFOSA and PFOS concentrations significantly decreased, while the remaining six PFASs significantly increased between ages 70 and 75. However, between ages 75 and 80 all PFAS concentrations significantly decreased. Overall from age 70 to 80, concentrations of PFHxS, PFUnDA, PFNA, and PFDA showed a significant increase (7% to 34%), whereas concentrations of PFOSA, PFHpA, PFOS, and PFOA (-75% to -27%) significantly decreased. Over time PFHxS concentrations increased more among women, while PFHpA concentrations showed a greater decrease among men. From age 70 to age 80, spanning from 2001-2004 to 2011-2014, the PIVUS cohort showed decreases in circulating levels of some PFASs phased out of

  17. 10-year survival of total ankle arthroplasties

    PubMed Central

    2011-01-01

    Background and purpose There is an ongoing need to review large series of total ankle replacements (TARs) for monitoring of changes in practice and their outcome. 4 national registries, including the Swedish Ankle Register, have previously reported their 5-year results. We now present an extended series with a longer follow-up, and with a 10-year survival analysis. Patients and methods Records of uncemented 3-component TARs were retrospectively reviewed, determining risk factors such as age, sex, and diagnosis. Prosthetic survival rates were calculated with exchange or removal of components as endpoint—excluding incidental exchange of the polyethylene meniscus. Results Of the 780 prostheses implanted since 1993, 168 (22%) had been revised by June 15, 2010. The overall survival rate fell from 0.81 (95% CI: 0.79–0.83) at 5 years to 0.69 (95% CI: 0.67–0.71) at 10 years. The survival rate was higher, although not statistically significantly so, during the latter part of the period investigated. Excluding the STAR prosthesis, the survival rate for all the remaining designs was 0.78 at 10 years. Women below the age of 60 with osteoarthritis were at a higher risk of revision, but age did not influence the outcome in men or women with rheumatoid arthritis. Revisions due to technical mistakes at the index surgery and instability were undertaken earlier than revisions for other reasons. Interpretation The results have slowly improved during the 18-year period investigated. However, we do not believe that the survival rates of ankle replacements in the near future will approach those of hip and knee replacements—even though improved instrumentation and design of the prostheses, together with better patient selection, will presumably give better results. PMID:22066551

  18. Natural History of Thyroid Function in Adults with Down Syndrome--10-Year Follow-Up Study

    ERIC Educational Resources Information Center

    Prasher, V.; Gomez, G.

    2007-01-01

    Background: The natural history of thyroid function in adults with Down syndrome (DS) is unknown. Method: This study investigated annual thyroid function tests in 200 adults with DS over a 10-year period. Results: Transient and persistent thyroid dysfunction was common. The 5- and 10-year incidence of definite hypothyroidism was 0.9%-1.64% and…

  19. Swift: 10 Years of Discovery

    NASA Astrophysics Data System (ADS)

    The conference Swift: 10 years of discovery was held in Roma at La Sapienza University on Dec. 2-5 2014 to celebrate 10 years of Swift successes. Thanks to a large attendance and a lively program, it provided the opportunity to review recent advances of our knowledge of the high-energy transient Universe both from the observational and theoretical sides. When Swift was launched on November 20, 2004, its prime objective was to chase Gamma-Ray Bursts and deepen our knowledge of these cosmic explosions. And so it did, unveiling the secrets of long and short GRBs. However, its multi-wavelength instrumentation and fast scheduling capabilities made it the most versatile mission ever flown. Besides GRBs, Swift has observed, and contributed to our understanding of, an impressive variety of targets including AGNs, supernovae, pulsars, microquasars, novae, variable stars, comets, and much more. Swift is continuously discovering rare and surprising events distributed over a wide range of redshifts, out to the most distant transient objects in the Universe. Such a trove of discoveries has been addressed during the conference with sessions dedicated to each class of events. Indeed, the conference in Rome was a spectacular celebration of the Swift 10th anniversary. It included sessions on all types of transient and steady sources. Top scientists from around the world gave invited and contributed talks. There was a large poster session, sumptuous lunches, news interviews and a glorious banquet with officials attending from INAF and ASI. All the presentations, as well as several conference pictures, can be found in the conference website (http://www.brera.inaf.it/Swift10/Welcome.html). These proceedings have been collected owing to the efforts of Paolo D’Avanzo who has followed each paper from submission to final acceptance. Our warmest thanks to Paolo for all his work. The Conference has been made possible by the support from La Sapienza University as well as from the ARAP

  20. Pediatric lung transplantation: 10 years of experience

    PubMed Central

    Camargo, Priscila C. L. B.; Pato, Eduardo Z. S.; Campos, Silvia V.; Afonso, José E.; Carraro, Rafael M.; Costa, André N.; Teixeira, Ricardo H. O. B.; Samano, Marcos N.; Pêgo-Fernandes, Paulo M.

    2014-01-01

    Lung transplantation is a well-established treatment for advanced lung diseases. In children, the diseases that most commonly lead to the need for a transplantation are cystic fibrosis, pulmonary hypertension, and bronchiolitis. However, the number of pediatric lung transplantations being performed is low compared with the number of transplants performed in the adult age group. The objective of this study was to demonstrate our experience with pediatric lung transplants over a 10-year period in a program initially designed for adults. PMID:24860860

  1. Optogenetics: 10 years of microbial opsins in neuroscience.

    PubMed

    Deisseroth, Karl

    2015-09-01

    Over the past 10 years, the development and convergence of microbial opsin engineering, modular genetic methods for cell-type targeting and optical strategies for guiding light through tissue have enabled versatile optical control of defined cells in living systems, defining modern optogenetics. Despite widespread recognition of the importance of spatiotemporally precise causal control over cellular signaling, for nearly the first half (2005-2009) of this 10-year period, as optogenetics was being created, there were difficulties in implementation, few publications and limited biological findings. In contrast, the ensuing years have witnessed a substantial acceleration in the application domain, with the publication of thousands of discoveries and insights into the function of nervous systems and beyond. This Historical Commentary reflects on the scientific landscape of this decade-long transition.

  2. Optogenetics: 10 years of microbial opsins in neuroscience

    PubMed Central

    Deisseroth, Karl

    2016-01-01

    Over the past 10 years, the development and convergence of microbial opsin engineering, modular genetic methods for cell-type targeting and optical strategies for guiding light through tissue have enabled versatile optical control of defined cells in living systems, defining modern optogenetics. Despite widespread recognition of the importance of spatiotemporally precise causal control over cellular signaling, for nearly the first half (2005–2009) of this 10-year period, as optogenetics was being created, there were difficulties in implementation, few publications and limited biological findings. In contrast, the ensuing years have witnessed a substantial acceleration in the application domain, with the publication of thousands of discoveries and insights into the function of nervous systems and beyond. This Historical Commentary reflects on the scientific landscape of this decade-long transition. PMID:26308982

  3. Detection of ectopic gastric mucosa in Meckel's diverticulum and in other aberrations by scintigraphy: ii. indications and methods--a 10-year experience.

    PubMed

    Sfakianakis, G N; Conway, J J

    1981-08-01

    Ten years' experience with pertechnetate (Tc-99m) abdominal scintigraphy has shown that the method is specifically indicated for the diagnosis and location of ectopic gastric mucosa in a Meckel's diverticulum, in enteric or gastric duplications and cysts, and in Barrett's esophagus. Careful patient preparation is essential, and sequential gamma camera imaging for 1 hr in the anterior projection is advisable, with complementary lateral, upright, and postvoiding views. Nonspecific accumulations of the tracer within tumours, intestinal obstructions, arteriovenous malformations, and the urinary tract can be recognized with the help of the clinical history and can be investigated by other tests. This approach has raised the accuracy of the method above 90%.

  4. Determination of selected cardiovascular active compounds in environmental aquatic samples--Methods and results, a review of global publications from the last 10 years.

    PubMed

    Stankiewicz, Albert; Giebułtowicz, Joanna; Stankiewicz, Urszula; Wroczyński, Piotr; Nałęcz-Jawecki, Grzegorz

    2015-11-01

    In recent years cardiovascular diseases were the second most common cause of death worldwide. Therefore, the consumption of cardiovascular drugs is high, which might result in an increase of them in the environment. The major source of aquatic environmental contamination is still effluents of wastewater treatment plants (WWTPs). Unfortunately removal of cardiovascular active compounds and/or their metabolites in WWTP is still unsatisfactory. Among microbial and abiotic degradation of these compounds during wastewater processes, photolysis and photodegradation of cardiovascular drugs also play an important role. New formed compounds may be more toxic or retain the properties of parent compounds. Thus the main goal of this paper was to provide a detailed and comprehensive review of used analytical methods, coupled to liquid chromatography-tandem mass spectrometry, to determine the presence of cardiovascular compounds in surface waters as well as WTTPs effluents and influents. Exhaustive preparation for mass spectrometry detection and quantitation including samples pre-treatment, and the common problem of the matrix effect are thoroughly explored in this paper. Additionally, the article provides some hints in respect of recently noted problematic issue related to the availability of specific standards for the analysis of drug's metabolites. Furthermore, information concerning the metabolism of cardiovascular active compounds including differences in metabolism within enantiomers is described. This article also touches on the problems associated with environmental risk assessment due to the presence of cardiovasculars in the environment. The paper also tries to explain differences in concentrations among cardiovascular compounds between countries worldwide.

  5. Administrative Reinstatement Interlock Programs: Florida, a 10-Year Study

    PubMed Central

    Voas, Robert B.; Tippetts, A. Scott; Grosz, Milton

    2013-01-01

    Background Interlocks reduce driving-under-the-influence (DUI) recidivism by 64%, but offenders resist installing them, preferring to risk driving while their driver’s licenses are revoked. One method of motivating offenders to install an interlock is require it for reinstatement of their driver’s license. This report updates an earlier evaluation of the administrative reinstatement interlock program (ARIP) procedure implemented in Florida in 2002. Method Driver records and interlock program records covering 120,000 DUI offenders were followed over 10 years. The flow through the sanction system—conviction, reinstatement, interlock program, and postinterlock period—is described. Logistical regression was used to identify the characteristics of offenders who installed interlocks, and survival analysis was used to evaluate the recidivism of offenders in the various stages in the ARIP. Results At any given time, approximately one third of the convicted offenders were serving their license-revocation periods. Half of the offenders who completed their revocation periods remain unqualified for reinstatement because they do not fulfill other requirements. ARIP offenders who do qualify for reinstatement and install interlocks have lower recidivism rates while the devices are on their vehicles. Conclusions After 10 years, Florida’s ARIP is a mature system that succeeds in forcing all offenders in the program who qualify for reinstatement to install an interlock for at least 6 months. However, half of all offenders who complete their mandatory revocation period are either unable to, or choose not to, qualify for reinstatement. PMID:23442206

  6. Photovoltaics - 10 years after Cherry Hill

    SciTech Connect

    Ralph, E.L.

    1984-05-01

    The question is, could a workshop today be effective in planning the next 10 years of development in the PV industry. Given is some insight into the Cherry Hill workshop, who was there and what was accomplished. Plans were made at workshop sessions, open panels discussed the needs, and invited papers were presented by experts in the field showing what concepts and ideas existed. The need for U.S. Government support of a 10 year PV development program was confirmed.

  7. Forward Period Analysis Method of the Periodic Hamiltonian System

    PubMed Central

    Wang, Pengfei

    2016-01-01

    Using the forward period analysis (FPA), we obtain the period of a Morse oscillator and mathematical pendulum system, with the accuracy of 100 significant digits. From these results, the long-term [0, 1060] (time unit) solutions, ranging from the Planck time to the age of the universe, are computed reliably and quickly with a parallel multiple-precision Taylor series (PMT) scheme. The application of FPA to periodic systems can greatly reduce the computation time of long-term reliable simulations. This scheme provides an efficient way to generate reference solutions, against which long-term simulations using other schemes can be tested. PMID:27727295

  8. "JPBI" 10 Years Later: Trends in Research Studies

    ERIC Educational Resources Information Center

    O'Dell, Sean M.; Vilardo, Brigid A.; Kern, Lee; Kokina, Anastasia; Ash, Allison N.; Seymour, Kimberly J.; Castrantas, Lauren M.; Kollar, Rachel B.; Wagner, Andrea M.; Bartholomew, Audrey; Thomas, Lisa B.

    2011-01-01

    In 2008, the "Journal of Positive Behavior Interventions" ("JPBI") celebrated 10 years in publication. As the flagship journal of positive behavior support (PBS), it is important to periodically examine the research published in "JPBI" to determine whether it reflects the basic principles of PBS, to explore the ways in which PBS is being…

  9. [10 years of liver transplantation in Peru].

    PubMed

    Chaman Ortiz, José Carlos; Padilla Machaca, P Martín; Rondon Leyva, Carlos; Carrasco Mascaró, Felix

    2010-01-01

    The article reviews the experience in 10 years of hepatic transplants performed by The Transplant Department of the National Hospital Guillermo Almenara Irigoyen (HNGAI), describing the history, surgical outcomes in adults and children, retransplantation, combined liver-kidney transplants, complications in 72 transplants performed at the time of submission of the article.

  10. Operations, Maintenance, and Replacement 10-Year Plan, 1990 -1999.

    SciTech Connect

    United States. Bonneville Power Administration.

    1990-08-01

    In 1988 Bonneville Power Administration (BPA) began work on this Operations, Maintenance, and Replacement 10-Year Plan to develop a levelized program that would assure high system reliability. During the Programs in Perspective (PIP) meetings in the late summer and fall of 1988, many of the concerns to be addressed in an Operations, Maintenance, and Replacement Plan were identified. Following these PIP meetings BPA established internal work groups. During the winter and spring of 1989, these work groups developed technical background and issue papers on topics that ranged from substation maintenance to environmental protection. In addition, a customer forum group was established and met on several occasions to review work on the plan, to offer ideas and points of view, and to assure that BPA understood customer concerns. Based on recommendations from the work group reports and customer input, BPA's O M Management Team developed the draft Operations, Maintenance, and Replacement 10-Year Plan that was released for public comment during the spring of 1990. During the public review period, BPA received a number of written comments from customers and the interested public. In addition, special meetings were held with interested customers. This final Operations, Maintenance, and Replacement 10-Year Plan reflects BPA's response to customers and interested public on each topic discussed in the 10-Year Plan. The plan is a distillation of BPA's strategies to achieve a levelized program over 10 years.

  11. Operations, Maintenance, and Replacement 10-Year Plan, 1990--1999

    SciTech Connect

    Not Available

    1990-08-01

    In 1988 Bonneville Power Administration (BPA) began work on this Operations, Maintenance, and Replacement 10-Year Plan to develop a levelized program that would assure high system reliability. During the Programs in Perspective (PIP) meetings in the later summer and fall of 1988, many of the concerns to be addressed in an Operations, Maintenance, and Replacement Plan were identified. Following these PIP meetings BPA established internal work groups. During the winter and spring of 1989, these work groups developed technical background and issue papers on topics that ranged from substation maintenance to environmental protection. In addition, a customer forum group was established and met on several occasions to review work on the plan, to offer ideas and points of view, and to assure that BPA understood customer concerns. Based on recommendations from the work group reports and customer input, BPA's O M Management Team developed the draft Operations, Maintenance, and Replacement 10-Year Plan that was released for public comment during the spring of 1990. During the public review period, BPA received a number of written comments from customers and the interested public. In addition, special meetings were held with interested customers. This final Operations, Maintenance, and Replacement 10-year Plan reflects BPA's response to customers and interested public on each topic discussed in the 10-Year Plan. The plan is a distillation of BPA's strategies to achieve a levelized program over 10 years.

  12. Neurology--the next 10 years.

    PubMed

    Baron, Ralf; Ferriero, Donna M; Frisoni, Giovanni B; Bettegowda, Chetan; Gokaslan, Ziya L; Kessler, John A; Vezzani, Annamaria; Waxman, Stephen G; Jarius, Sven; Wildemann, Brigitte; Weller, Michael

    2015-11-01

    Since the launch of our journal as Nature Clinical Practice Neurology in 2005, we have seen remarkable progress in many areas of neurology research, but what does the future hold? Will advances in basic research be translated into effective disease-modifying therapies, and will personalized medicine finally become a reality? For this special Viewpoint article, we invited a panel of Advisory Board members and other journal contributors to outline their research priorities and predictions in neurology for the next 10 years.

  13. Photovoltaics - 10 years after Cherry Hill

    NASA Astrophysics Data System (ADS)

    Ralph, E. L.

    The status of R&D programs connected with photovoltaic (PV) systems 10 years after the Cherry Hill workshop on 'Photovoltaic Conversion of Solar Energy for Terrestrial Applications' is assessed. The five categories of research recommended by the Cherry Hill Workshop are listed in a table together with their recommended research budget allocations. The workshop categories include: single-crystal Si cells; poly-Si cells; systems and diagnostics. Categories for thin film CdS/Cu2S and CuInSe2 cells are also included. The roles of government and private utility companies in providing adequate financial support for PV research programs is emphasized.

  14. Mitochondrial ROS Metabolism: 10 Years Later

    PubMed Central

    Kushnareva, Y. E.; Murphy, A. N.

    2015-01-01

    The role of mitochondria in oxidative stress is well recognized, but many questions are still to be answered. This article is intended to update our comprehensive review in 2005 by highlighting the progress in understanding of mitochondrial reactive oxygen species (ROS) metabolism over the past 10 years. We review the recently identified or re-appraised sources of ROS generation in mitochondria, such as p66shc protein, succinate dehydrogenase, and recently discovered properties of the mitochondrial antioxidant system. We also reflect upon some controversies, disputes, and misconceptions that confound the field. PMID:26071769

  15. Expected innovations of optical lithography in the next 10 years

    NASA Astrophysics Data System (ADS)

    Owa, Soichi; Hirayanagi, Noriyuki

    2016-03-01

    In the past 10 years, immersion lithography has been the most effective high volume manufacturing method for the critical layers of semiconductor devices. Thinking of the next 10 years, we can expect continuous improvement on existing 300 mm wafer scanners with better accuracy and throughput to enhance the total output value per input cost. This value productivity, however, can be upgraded also by larger innovations which might happen in optical lithography. In this paper, we will discuss the possibilities and the impossibilities of potential innovation ideas of optical lithography, which are 450 mm wafer, optical maskless, multicolor lithography, and metamaterial.

  16. Snowmobile trauma: 10 years' experience at Manitoba's tertiary trauma centre

    PubMed Central

    Stewart, Rena L.; Black, G. Brian

    2004-01-01

    Introduction According to the literature, the increased recreational use of the snowmobile has resulted in an increasing number of musculoskeletal injuries. We wished to examine whether previously described risk factors continue to be associated with snowmobile trauma and to identify previously unrecognized risks and specific patterns of injury. Methods We carried out a chart review of all snowmobile-related injuries over a 10-year period at the Health Sciences Centre in Winnipeg, the only level 1 trauma centre serving the Province of Manitoba, with particular attention to the risk factors of suboptimal lighting, excessive speed and alcohol consumption. Results We identified 480 injuries in 294 patients, and 81 (27.6%) of these patients died. Collisions accounted for 72% of the injury mechanisms. Of the injuries sustained, 31% occurred on roads. Excessive speed was a risk factor in 54% of patients, suboptimal lighting in 86% and a blood alcohol level greater than 0.08 in 70%. Musculoskeletal injuries accounted for 57% of those recorded. There were also brachial plexus injuries (3%) and knee dislocations (2%). To our knowledge, this is the largest study detailing injury associated with recreational use of snowmobiles in Canada. Conclusions Because snowmobile trauma is caused principally by human errors, it is potentially preventable. Efforts aimed at prevention must focus on the driver, who controls the common risk factors. The danger of snowmobiling while intoxicated must be emphasized. Trail-side monitoring is likely to be ineffective, as the majority of accidents do not occur on designated snowmobile trails. PMID:15132460

  17. Aqua's First 10 Years: An Overview

    NASA Technical Reports Server (NTRS)

    Parkinson, Claire L.

    2012-01-01

    NASA's Aqua spacecraft was launched at 2:55 a.m. on May 4, 2002, from Vandenberg Air Force Base in California, into a near-polar, sun-synchronous orbit at an altitude of 705 km. Aqua carries six Earth-observing instruments to collect data on water in all its forms (liquid, vapor, and solid) and on a wide variety of additional Earth system variables (Parkinson 2003). The design lifetime for Aqua's prime mission was 6 years, and Aqua is now well into its extended mission, approaching 10 years of successful operations. The Aqua data have been used for hundreds of scientific studies and continue to be used for scientific discovery and numerous practical applications.

  18. 10-year evapotranspiration estimates in a Bornean tropical rainforest

    NASA Astrophysics Data System (ADS)

    Kume, T.; Tanaka, N.; Komatsu, H.; Yoshifuji, N.; Saitoh, T. M.; Suzuki, M.; Kumagai, T.

    2010-12-01

    This study was undertaken to quantify 10-year evapotranspiration (ET) in a tropical rainforest, Sarawak, Malaysia. To this aim, a simplified big-leaf model was formulated, which can consider transpiration (Et) and rainfall interception (Ei). The model was independently validated using eddy covariance fluxes, rainfall interception based on throughfall and stemflow measurements, and sap flow measurements conducted for more than two years. Consequently, our big-leaf model could successfully reproduce Et and Ei. By using the model and a 10-year meteorological data set, Et, Ei, and ET was estimated in the period between 2000 and 2009. The annual Et , Ei, and ET averaged over 10 years were estimated as 1114, 209, and 1323 mm, respectively, with the small seasonal fluctuations. The derived estimations for 10 years showed conservative year-to-year variations in Et, Ei, and ET (CV = 5-7%) against considerable year-to-year variations in annual rainfall (CV = 11%). Specific rainfall characteristics in this site could be a reason for conservative year-to-year variations in Ei. Small interannual variations in meteorological conditions and no occurrence of unusually severe drought in this study period could be a reason for the small year-to-year variations in Et. As well, we compared ET, Ei at this site with those of other tropical forests. Our forest ET was smaller than global maximum value of ET estimated in other tropical forests because of the smaller Ei, relative to annual rainfall at this site. Based on the derived characteristics of ET, we also discussed possible changes in ET, Et, and Ei in response to changes in rainfall regime at this site.

  19. Numerical matrix method for quantum periodic potentials

    NASA Astrophysics Data System (ADS)

    Le Vot, Felipe; Meléndez, Juan J.; Yuste, Santos B.

    2016-06-01

    A numerical matrix methodology is applied to quantum problems with periodic potentials. The procedure consists essentially in replacing the true potential by an alternative one, restricted by an infinite square well, and in expressing the wave functions as finite superpositions of eigenfunctions of the infinite well. A matrix eigenvalue equation then yields the energy levels of the periodic potential within an acceptable accuracy. The methodology has been successfully used to deal with problems based on the well-known Kronig-Penney (KP) model. Besides the original model, these problems are a dimerized KP solid, a KP solid containing a surface, and a KP solid under an external field. A short list of additional problems that can be solved with this procedure is presented.

  20. Justification for Rhinoseptoplasty in Children – Our 10 Years Overview

    PubMed Central

    Kopacheva-Barsova, Gabriela; Nikolovski, Nikola

    2016-01-01

    BACKGROUND: Nasal septal surgery and rhinoplasty are controversial in children. Traditionally, an attitude of restraint has been employed by most surgeons till an empirical age of 16 to 18 years. This is to avoid the possible adverse effects that the growth spurts may have on the nose and midface region. AIM: The aim of this paper was to present the results of rhinoplasty in children in order to restore the anatomy and function or to promote normal development and outgrowth of the nose. MATERIAL AND METHODS: Ninety seven children aged 6-14, with severe nose deformities and breathing problems through the nose, were admitted for septo/rhinoplasty at the University Clinic for Ear, Nose and Throat, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Republic of Macedonia. At our Clinic, they have been observed and photographed (with parent permission) in the period of 10 years (2006-2016). The most frequent cause of these deformities was the nasal trauma in early childhood which was ignored or untreated. All of them rhino/septoplasty were indicated in accordance with the above-mentioned recommendations for rhino/septoplasty in early childhood and in adolescents. RESULTS: In 51 children and adolescents septoplasty were prepared. Mostly there was a group of younger children age from 6-10 (68%) and adolescents (32%). In the other 31 children and adolescents, septorhinoplasty was prepared. Mostly there were children older than 12 years old and adolescents (70%). Only 30% were younger than 12 years, of course with severe nasal breathing problems, nasal septal deformities and deformities of the nasal pyramid. CONCLUSION: The growth centres of the nose have to be avoided if possible; long-term nasal issues will theoretically be minimised. If the surgeon replaces it, the cartilage of the nose becomes straighter but still intact.

  1. Childhood AIDS nephropathy: a 10-year experience.

    PubMed Central

    Rajpoot, D.; Kaupke, C. J.; Vaziri, N. D.; Rao, T. K.; Pomrantz, A.; Fikrig, S.

    1996-01-01

    The objective of this study was to define the demographic, immunologic, and clinical characteristics of children with acquired immunodeficiency syndrome (AIDS) and AIDS nephropathy, and contrast this with the existing adult data. Data from 62 pediatric patients with AIDS who were treated at SUNY Health Science Center, Brooklyn, New York, between 1983 and 1993 were analyzed. Human immunodeficiency virus (HIV) infection was acquired during the neonatal period by vertical transmission (n = 60) or blood transfusion (n = 2). All children with AIDS who exhibited clinical nephropathy died (n = 16), with mean survival of 55.3 months. In contrast, 32 of 56 AIDS patients (70%) who did not manifest nephropathy were alive at the end of the study period. Patients with nephropathy were noted to have significantly lower CD4+ lymphocyte counts than those without nephropathy. These observations suggest that the predominant renal lesion in pediatric patients who acquired HIV infection during the perinatal period is focal segmental glomerulosclerosis, although a variety of other histological lesions were present. As in adults, the survival in children is dismal following the onset of clinical renal disease. In contrast to the adult population in whom multiple risk factors can potentially contribute to AIDS-associated nephropathy, occurrence of nephropathy in children with vertical HIV transmission provides convincing evidence for the pathogenetic role of HIV infection. PMID:8803430

  2. Makaton Peer Tutoring Evaluation: 10 Years On.

    ERIC Educational Resources Information Center

    Hooper, Helen; Walker, Margaret

    2002-01-01

    A survey of 23 establishments found 16 were still very active in using the Makaton peer tutoring method and reported that the method had not only contributed to an increase in communication and the effectiveness of interactions, but had also resulted in increased self-esteem, confidence, and assertiveness. (Contains references.) (CR)

  3. Trabecular metal tibial knee component still stable at 10 years

    PubMed Central

    Henricson, Anders; Nilsson, Kjell G

    2016-01-01

    Background and purpose Total knee replacement (TKR) in younger patients using cemented components has shown inferior results, mainly due to aseptic loosening. Excellent clinical results have been reported with components made of trabecular metal (TM). In a previous report, we have shown stabilization of the TM tibial implants for up to 5 years. In this study, we compared the clinical and RSA results of these uncemented implants with those of cemented implants. Patients and methods 41 patients (47 knees) aged ≤ 60 years underwent TKR. 22 patients (26 knees) received an uncemented monoblock cruciate-retaining (CR) tibial component (TM) and 19 patients (21 knees) received a cemented NexGen Option CR tibial component. Follow-up examination was done at 10 years, and 16 patients (19 knees) with TM tibial components and 17 patients (18 knees) with cemented tibial components remained for analysis. Results 1 of 19 TM implants was revised for infection, 2 of 18 cemented components were revised for knee instability, and no revisions were done for loosening. Both types of tibial components migrated in the first 3 months, the TM group to a greater extent than the cemented group. After 3 months, both groups were stable during the next 10 years. Interpretation The patterns of migration for uncemented TM implants and cemented tibial implants over the first 10 years indicate that they have a good long-term prognosis regarding fixation PMID:27357222

  4. Trabecular metal tibial knee component still stable at 10 years.

    PubMed

    Henricson, Anders; Nilsson, Kjell G

    2016-10-01

    Background and purpose - Total knee replacement (TKR) in younger patients using cemented components has shown inferior results, mainly due to aseptic loosening. Excellent clinical results have been reported with components made of trabecular metal (TM). In a previous report, we have shown stabilization of the TM tibial implants for up to 5 years. In this study, we compared the clinical and RSA results of these uncemented implants with those of cemented implants. Patients and methods - 41 patients (47 knees) aged ≤ 60 years underwent TKR. 22 patients (26 knees) received an uncemented monoblock cruciate-retaining (CR) tibial component (TM) and 19 patients (21 knees) received a cemented NexGen Option CR tibial component. Follow-up examination was done at 10 years, and 16 patients (19 knees) with TM tibial components and 17 patients (18 knees) with cemented tibial components remained for analysis. Results - 1 of 19 TM implants was revised for infection, 2 of 18 cemented components were revised for knee instability, and no revisions were done for loosening. Both types of tibial components migrated in the first 3 months, the TM group to a greater extent than the cemented group. After 3 months, both groups were stable during the next 10 years. Interpretation - The patterns of migration for uncemented TM implants and cemented tibial implants over the first 10 years indicate that they have a good long-term prognosis regarding fixation. PMID:27357222

  5. 7 CFR 625.9 - 10-year restoration cost-share agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false 10-year restoration cost-share agreements. 625.9... restoration cost-share agreements. (a) The restoration plan developed under § 625.12 forms the basis for the...) Incorporate all portions of a restoration plan; (2) Be for a period of 10 years; (3) Include all provisions...

  6. 7 CFR 625.9 - 10-year restoration cost-share agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false 10-year restoration cost-share agreements. 625.9... restoration cost-share agreements. (a) The restoration plan developed under § 625.13 forms the basis for the... agreement will: (1) Incorporate all portions of a restoration plan; (2) Be for a period of 10 years;...

  7. Periodization

    PubMed Central

    Lorenz, Daniel S.; Reiman, Michael P.; Walker, John C.

    2010-01-01

    Background: Clinicians are constantly faced with the challenge of designing training programs for injured and noninjured athletes that maximize healing and optimize performance. Periodization is a concept of systematic progression—that is, resistance training programs that follow predictable patterns of change in training variables. The strength training literature is abundant with studies comparing periodization schemes on uninjured, trained, and untrained athletes. The rehabilitation literature, however, is scarce with information about how to optimally design resistance training programs based on periodization principles for injured athletes. The purpose of this review is to discuss relevant training variables and methods of periodization, as well as periodization program outcomes. A secondary purpose is to provide an anecdotal framework regarding implementation of periodization principles into rehabilitation programs. Evidence Acquisition: A Medline search from 1979 to 2009 was implemented with the keywords periodization, strength training, rehabilitation, endurance, power, hypertrophy, and resistance training with the Boolean term AND in all possible combinations in the English language. Each author also undertook independent hand searching of article references used in this review. Results: Based on the studies researched, periodized strength training regimens demonstrate improved outcomes as compared to nonperiodized programs. Conclusions: Despite the evidence in the strength training literature supporting periodization programs, there is a considerable lack of data in the rehabilitation literature about program design and successful implementation of periodization into rehabilitation programs. PMID:23015982

  8. Draft 1992 : Operations, Maintenance, and Replacement 10-Year Plan.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-05-01

    Two years ago, BPA released its first-ever Operations, Maintenance, and Replacement (OM&R) 10-Year Plan. That effort broke new ground and was an extensive look at the condition of Operations, Maintenance, and Replacement on BPA`s power system. This document -- the 1992 OM&R 10-Year Plan -- uses that original plan as its foundation. It takes a look at how well BPA has accomplished the challenging task set out in the 1990 Plan. The 1992 Plan also introduces the Construction Program. Construction`s critical role in these programs is explored, and the pressures of construction workload -- such as the seasonal nature of the work and the broad swings in workload between projects and years -- are discussed. The document then looks at how situations may have changed with issues explored initially in the 1990 Plan. Importantly, this Plan also surfaces and explains some new issues that threaten to impact BPA`s ability to accomplish its OM&R workload. Finally, the document focuses on the revised strategies for Operations, Maintenance, Replacement, Construction, and Environment for the 1992 to 2001 time period, including the financial and human resources needed to accomplish those strategies.

  9. [Wavelet analysis on SO2 pollution index changes of Shanghai in recent 10 years].

    PubMed

    Wu, Xiao-ling; Zhang, Bin; Ai, Nan-shan; Liu, Li-jun

    2009-08-15

    Based on the continuous Mexican Hat wavelet transformation of time series of daily SO2 pollution index during last 10 years in Shanghai, the multiscale variations, primary period, catastrophe point and influencing factors are analyzed. The result shows that periodical fluctuation of SO2 pollution index varies at diverse time-scales, and the primary period of the daily variations is about 100 days; pollution pattern takes on serious in winter and light in summer in most scales due to meteorological conditions, and the catastrophe point of serious-light transformation of SO2 pollution index in a year is vernal and autumnal equinox; energy demand and socioeconomic development result in more seriousness in recent years and half result with twice the effort of endeavors of pollution elimination. Wavelet analysis is an effective method to time series of SO2 pollution index, also to multiscale variations of other pollutants. PMID:19799273

  10. Effects of Two Modes of Exercise Training on Physical Fitness of 10 Year-Old Children

    ERIC Educational Resources Information Center

    Ribeiro, Ligia G. dos Santos Chaves; Portal, Maria de Nazare Dias; da Silva, Joao Bittencourt; Saraiva, Alan; da Cruz Monte, Gerson, Jr.; Dantas, Estelio H. M.

    2010-01-01

    Study aim: To compare two exercise training modes on the physical fitness of 10 year-old children. Material and methods: A sample of 60 schoolboys aged 10 years were randomly divided into 3 groups: Traditional (TG), trained according to the Brazilian national curricular parameters, Maturational (MG), in which the degree of difficulty of the…

  11. Anaerobic bacteraemia: a 10-year retrospective epidemiological survey.

    PubMed

    De Keukeleire, Steven; Wybo, Ingrid; Naessens, Anne; Echahidi, Fedoua; Van der Beken, Mieke; Vandoorslaer, Kristof; Vermeulen, Stefan; Piérard, Denis

    2016-06-01

    In order to identify current trends in anaerobic bacteraemia, a 10-year retrospective study was performed in the University Hospital Brussel, Belgium. All clinically relevant bacteraemia detected from 2004 until 2013 were included. Medical records were reviewed in an attempt to define clinical parameters that might be associated with the occurrence of anaerobic bacteraemia. 437 of the isolated organisms causing anaerobic bacteraemia were thawed, subcultured and reanalyzed using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF). There were an average of 33 cases of anaerobic bacteraemia per year during 2004-2008 compared to an average of 27 cases per year during 2009-2013 (P = 0.017), corresponding to a decrease by 19% between the first and the latter period. Also, the total number of cases of anaerobic bacteraemia per 100,000 patient days decreased from 17.3 in the period from 2004 to 2008 to 13.7 in the period 2009 to 2013 (P = 0.023). Additionally, the mean incidence of anaerobic bacteraemia decreased during the study period (1.27/1000 patients in 2004 vs. 0.94/1000 patients in 2013; P = 0.008). In contrast, the proportion of isolated anaerobic bacteraemia compared to the number of all bacteraemia remained stable at 5%. Bacteroides spp. and Parabacteroides spp. accounted for 47.1% of the anaerobes, followed by 14.4% Clostridium spp., 12.6% non-spore-forming Gram-positive rods, 10.5% anaerobic cocci, 8.2% Prevotella spp. and other Gram-negative rods and 7.1% Fusobacterium spp. The lower gastrointestinal tract (47%) and wound infections (10%) were the two most frequent sources for bacteraemia, with the origin remaining unknown in 62 cases (21%). The overall mortality rate was 14%. Further studies focusing on the antimicrobial susceptibility and demographic background of patients are needed to further objectify the currently observed trends.

  12. Linear Scaling Electronic Structure Methods with Periodic Boundary Conditions

    SciTech Connect

    Gustavo E. Scuseria

    2008-02-08

    The methodological development and computational implementation of linear scaling quantum chemistry methods for the accurate calculation of electronic structure and properties of periodic systems (solids, surfaces, and polymers) and their application to chemical problems of DOE relevance.

  13. Statistical methods for detecting periodic fragments in DNA sequence data

    PubMed Central

    2011-01-01

    Background Period 10 dinucleotides are structurally and functionally validated factors that influence the ability of DNA to form nucleosomes, histone core octamers. Robust identification of periodic signals in DNA sequences is therefore required to understand nucleosome organisation in genomes. While various techniques for identifying periodic components in genomic sequences have been proposed or adopted, the requirements for such techniques have not been considered in detail and confirmatory testing for a priori specified periods has not been developed. Results We compared the estimation accuracy and suitability for confirmatory testing of autocorrelation, discrete Fourier transform (DFT), integer period discrete Fourier transform (IPDFT) and a previously proposed Hybrid measure. A number of different statistical significance procedures were evaluated but a blockwise bootstrap proved superior. When applied to synthetic data whose period-10 signal had been eroded, or for which the signal was approximately period-10, the Hybrid technique exhibited superior properties during exploratory period estimation. In contrast, confirmatory testing using the blockwise bootstrap procedure identified IPDFT as having the greatest statistical power. These properties were validated on yeast sequences defined from a ChIP-chip study where the Hybrid metric confirmed the expected dominance of period-10 in nucleosome associated DNA but IPDFT identified more significant occurrences of period-10. Application to the whole genomes of yeast and mouse identified ~ 21% and ~ 19% respectively of these genomes as spanned by period-10 nucleosome positioning sequences (NPS). Conclusions For estimating the dominant period, we find the Hybrid period estimation method empirically to be the most effective for both eroded and approximate periodicity. The blockwise bootstrap was found to be effective as a significance measure, performing particularly well in the problem of period detection in the

  14. Circles South East: the first 10 years 2002-2012.

    PubMed

    Bates, Andrew; Williams, Dominic; Wilson, Chris; Wilson, Robin J

    2014-07-01

    This article describes the first 10 years of the implementation of Circles of Support and Accountability (Circles) in the management of sexual offenders in South-East England by Circles South East (CSE). The Circles of 71 core members are reviewed in detail, with reference to demographic data, offense and sentencing histories, risk assessment data, and considerations regarding Multi-Agency Public Protection Arrangements. A group of 71 comparison subjects who were referred to CSE and deemed suitable for but did not receive the service was identified. Follow-up behaviors of both groups are examined (including all forms of reconviction, breach of orders, and prison recall). Over a comparable follow-up period of 55 months, the incidence of violent and contact sexual reconviction in the comparison group was significantly higher than for the Circles cohort. Comparisons are made between expected and actual levels of sexual reconviction, with the Circles cohort showing lower than expected rate of sexual reconviction but not to a statistically significant degree.

  15. Fatal burns in Manipal area: a 10 year study.

    PubMed

    Kumar, Virendra; Mohanty, Manoj Kumar; Kanth, Sarita

    2007-01-01

    The purpose of this study was to record and evaluate the causes and the magnitude of the fatal burn injuries retrospectively. An analysis of autopsy records revealed 19.4% cases of burn injuries amongst the total autopsies done over 10years period (1993-2002) in the mortuary of the department of Forensic Medicine of Kasturba medical College, Manipal. The majority of deaths (78.5%) occurred between 11 and 40years of age group with preponderance of females (74.8%). The flame burns were seen in 94.1% of the victims followed by scalds and electrical burns in 2.8% and 2.5% cases, respectively. The majority of burn incidents were accidental (75.8%) in nature followed by suicidal (11.5%) and homicidal (3.1%) deaths. The percentage of burn (TBSA) over 40% were observed in most of the cases (92.5%). The majority of deaths occurred within a week (69.87%) and most the victims died because of septicemia (50.9%). PMID:17046310

  16. The Cryptophlebia Leucotreta Granulovirus—10 Years of Commercial Field Use

    PubMed Central

    Moore, Sean D.; Kirkman, Wayne; Richards, Garth I.; Stephen, Peter R.

    2015-01-01

    In the last 15 years, extensive work on the Cryptophlebia leucotreta granulovirus (CrleGV) has been conducted in South Africa, initially in the laboratory, but subsequently also in the field. This culminated in the registration of the first CrleGV-based biopesticide in 2004 (hence, the 10 years of commercial use in the field) and the second one three years later. Since 2000, more than 50 field trials have been conducted with CrleGV against the false codling moth, Thaumatotibia leucotreta, on citrus in South Africa. In a representative sample of 13 field trials reported over this period, efficacy (measured by reduction in larval infestation of fruit) ranged between 30% and 92%. Efficacy was shown to persist at a level of 70% for up to 17 weeks after application of CrleGV. This only occurred where the virus was applied in blocks rather than to single trees. The addition of molasses substantially and sometimes significantly enhanced efficacy. It was also established that CrleGV should not be applied at less than ~2 × 1013 OBs per ha in order to avoid compromised efficacy. As CrleGV-based products were shown to be at least as effective as chemical alternatives, persistent and compatible with natural enemies, their use is recommended within an integrated program for control of T. leucotreta on citrus and other crops. PMID:25809025

  17. 10 years of surveillance of human tularaemia in France.

    PubMed

    Mailles, A; Vaillant, V

    2014-11-13

    Tularaemia has been mandatorily notifiable in France since October 2002. The surveillance aims to detect early any infection possibly due to bioterrorism and to follow up disease trends. We report the results of national surveillance from 2002 to 2012. A case is defined as a patient with clinical presentation suggestive of tularaemia and biological confirmation of infection or an epidemiological link with a biologically confirmed case. Clinical, biological and epidemiological data are collected using a standardised notification form. From 2002 to 2012, 433 cases were notified, with a median age of 49 years (range 2 to 95 years) and a male–female sex ratio of 1.8. Most frequent clinical presentations were glandular tularaemia (n=200; 46%) and ulceroglandular tularaemia (n=113; 26%). Most frequent at-risk exposures were handling hares (n=179; 41%) and outdoor leisure exposure to dust aerosols (n=217; 50%). Tick bites were reported by 82 patients (19%). Ten clusters (39 cases) were detected over the 10-year period, as well as a national outbreak during winter 2007/2008. The tularaemia surveillance system is able to detect small clusters as well as major outbreaks. Surveillance data show exposure to dust aerosols during outdoor leisure activities to be a major source of contamination in France.

  18. Temporal Validation of the UKPDS Outcomes Model Using 10-Year Posttrial Monitoring Data

    PubMed Central

    Leal, Jose; Hayes, Alison J.; Gray, Alastair M.; Holman, Rury R.; Clarke, Philip M.

    2013-01-01

    OBJECTIVE To evaluate the accuracy of the UK Prospective Diabetes Study Outcomes Model (UKPDS-OM) in predicting clinical outcomes during the UKPDS posttrial monitoring (PTM) period. RESEARCH DESIGN AND METHODS At trial end in 1997, the 4,031 surviving UKPDS patients, of the 5,102 originally enrolled in the study, returned to their usual care providers, with no attempts made to maintain them in their randomized therapy groups. PTM risk factor data were collected for 5 years and clinical outcome data for 10 years. The UKPDS-OM was used firstly to forecast likely progression of HbA1c, systolic blood pressure, total-to-HDL cholesterol ratio, and smoking status and secondly to estimate the likely first occurrence of seven major diabetes-related complications or death from any cause. Model predictions were compared against observed PTM data for risk factor time paths and survival probabilities for major diabetes complications. RESULTS UKPDS-OM–forecasted risk factor time paths were similar to those observed for HbA1c (up to 3 years) and total-to-HDL cholesterol ratio but underestimated for systolic blood pressure and smoking status. Predicted 10-year event probabilities were similar to those observed for blindness, ischemic heart disease, myocardial infarction, and renal failure but were higher for heart failure and death from any cause and lower for stroke and amputation. CONCLUSIONS The UKPDS-OM has good predictive accuracy for two of four risk factor time paths and for 10-year clinical outcome probabilities with the exception of stroke, amputation, heart failure, and death from any cause. An updated version of the model incorporating PTM data is being developed. PMID:23275370

  19. A method of periodic pattern localization on document images

    NASA Astrophysics Data System (ADS)

    Chernov, Timofey S.; Nikolaev, Dmitry P.; Kliatskine, Vitali M.

    2015-12-01

    Periodic patterns often present on document images as holograms, watermarks or guilloche elements which are mostly used for fraud protection. Localization of such patterns lets an embedded OCR system to vary its settings depending on pattern presence in particular image regions and improves the precision of pattern removal to preserve as much useful data as possible. Many document images' noise detection and removal methods deal with unstructured noise or clutter on documents with simple background. In this paper we propose a method of periodic pattern localization on document images which uses discrete Fourier transform that works well on documents with complex background.

  20. Personality disorder risk factors for suicide attempts over 10 years of follow-up.

    PubMed

    Ansell, Emily B; Wright, Aidan G C; Markowitz, John C; Sanislow, Charles A; Hopwood, Christopher J; Zanarini, Mary C; Yen, Shirley; Pinto, Anthony; McGlashan, Thomas H; Grilo, Carlos M

    2015-04-01

    Identifying personality disorder (PD) risk factors for suicide attempts is an important consideration for research and clinical care alike. However, most prior research has focused on single PDs or categorical PD diagnoses without considering unique influences of different PDs or of severity (sum) of PD criteria on the risk for suicide-related outcomes. This has usually been done with cross-sectional or retrospective assessment methods. Rarely are dimensional models of PDs examined in longitudinal, naturalistic prospective designs. In addition, it is important to consider divergent risk factors in predicting the risk of ever making a suicide attempt versus the risk of making an increasing number of attempts within the same model. This study examined 431 participants who were followed for 10 years in the Collaborative Longitudinal Personality Disorders Study. Baseline assessments of personality disorder criteria were summed as dimensional counts of personality pathology and examined as predictors of suicide attempts reported at annual interviews throughout the 10-year follow-up period. We used univariate and multivariate zero-inflated Poisson regression models to simultaneously evaluate PD risk factors for ever attempting suicide and for increasing numbers of attempts among attempters. Consistent with prior research, borderline PD was uniquely associated with ever attempting. However, only narcissistic PD was uniquely associated with an increasing number of attempts. These findings highlight the relevance of both borderline and narcissistic personality pathology as unique contributors to suicide-related outcomes. PMID:25705977

  1. Alopecia Areata in the Elderly: A 10-Year Retrospective Study

    PubMed Central

    Jang, Yong Hyun; Park, Kyung Hea; Kim, Sang Lim; Lim, Hyun Jung; Lee, Weon Ju; Lee, Seok-Jong

    2015-01-01

    Background Alopecia areata (AA) is an organ-specific autoimmune disease that typically occurs in young adults. AA in the elderly is relatively rare, thus little data have been reported. Objective This study aimed to understand the clinical characteristics of AA in the elderly. Methods We performed a 10-year retrospective study of AA in the elderly who visited our dermatologic clinic from January 2002 to December 2011. A clinical review of medical records and telephone interviews were performed by two dermatologists. Results Among 1,761 patients with newly diagnosed AA, 61 (3.5%) were older than 60 years at the first visit. Among those who completed a telephone interview, 74.3% (26/35) had less than 50% of scalp-localized hair loss. There was no association between the extent of AA and hair graying (p=0.679). Favorable therapeutic response was observed in 62.9% (22/35) of cases. Conclusion AA in the elderly shows mild disease severity and favorable treatment response. There is no association between graying and the extent of AA. However, the influence of aging on the pathogenesis of AA in the elderly deserves further investigation. PMID:26273157

  2. Hybrid transfer-matrix FDTD method for layered periodic structures.

    PubMed

    Deinega, Alexei; Belousov, Sergei; Valuev, Ilya

    2009-03-15

    A hybrid transfer-matrix finite-difference time-domain (FDTD) method is proposed for modeling the optical properties of finite-width planar periodic structures. This method can also be applied for calculation of the photonic bands in infinite photonic crystals. We describe the procedure of evaluating the transfer-matrix elements by a special numerical FDTD simulation. The accuracy of the new method is tested by comparing computed transmission spectra of a 32-layered photonic crystal composed of spherical or ellipsoidal scatterers with the results of direct FDTD and layer-multiple-scattering calculations.

  3. Periodicity detection method for small-sample time series datasets.

    PubMed

    Tominaga, Daisuke

    2010-01-01

    Time series of gene expression often exhibit periodic behavior under the influence of multiple signal pathways, and are represented by a model that incorporates multiple harmonics and noise. Most of these data, which are observed using DNA microarrays, consist of few sampling points in time, but most periodicity detection methods require a relatively large number of sampling points. We have previously developed a detection algorithm based on the discrete Fourier transform and Akaike's information criterion. Here we demonstrate the performance of the algorithm for small-sample time series data through a comparison with conventional and newly proposed periodicity detection methods based on a statistical analysis of the power of harmonics.We show that this method has higher sensitivity for data consisting of multiple harmonics, and is more robust against noise than other methods. Although "combinatorial explosion" occurs for large datasets, the computational time is not a problem for small-sample datasets. The MATLAB/GNU Octave script of the algorithm is available on the author's web site: http://www.cbrc.jp/%7Etominaga/piccolo/. PMID:21151841

  4. Strengths and Limitations of Period Estimation Methods for Circadian Data

    PubMed Central

    Troup, Eilidh; Halliday, Karen J.; Millar, Andrew J.

    2014-01-01

    A key step in the analysis of circadian data is to make an accurate estimate of the underlying period. There are many different techniques and algorithms for determining period, all with different assumptions and with differing levels of complexity. Choosing which algorithm, which implementation and which measures of accuracy to use can offer many pitfalls, especially for the non-expert. We have developed the BioDare system, an online service allowing data-sharing (including public dissemination), data-processing and analysis. Circadian experiments are the main focus of BioDare hence performing period analysis is a major feature of the system. Six methods have been incorporated into BioDare: Enright and Lomb-Scargle periodograms, FFT-NLLS, mFourfit, MESA and Spectrum Resampling. Here we review those six techniques, explain the principles behind each algorithm and evaluate their performance. In order to quantify the methods' accuracy, we examine the algorithms against artificial mathematical test signals and model-generated mRNA data. Our re-implementation of each method in Java allows meaningful comparisons of the computational complexity and computing time associated with each algorithm. Finally, we provide guidelines on which algorithms are most appropriate for which data types, and recommendations on experimental design to extract optimal data for analysis. PMID:24809473

  5. Handedness in Swedish 10-year-olds, Some Background and Associated Factors.

    ERIC Educational Resources Information Center

    Gillberg, Christopher; And Others

    1984-01-01

    Aims to obtain prevalence figures for left-handedness among 10-year-old Swedish children; to replicate some findings concerning Bishop's (1980) extended pathological left-handedness hypothesis; to evaluate the influence of factors such as the child's sex and reduced optimality in the pre-, peri-, and neonatal period; and to determine the…

  6. Students as Teachers: Effectiveness of a Peer-Led STEM Learning Programme over 10 Years

    ERIC Educational Resources Information Center

    Drane, Denise; Micari, Marina; Light, Gregory

    2014-01-01

    Peer-led small-group learning has been used quite extensively in the US to enhance performance and retention of undergraduate students in science, math, and engineering classes. This study presents the results from an evaluation of a peer-led small-group programme at a research university in the US over a 10-year period across five disciplines…

  7. Optimism, Pessimism, Mutuality, and Gender: Predicting 10-Year Role Strain in Parkinson's Disease Spouses

    ERIC Educational Resources Information Center

    Lyons, Karen S.; Stewart, Barbara J.; Archbold, Patricia G.; Carter, Julie H.

    2009-01-01

    Purpose: There is wide variability in how spouses providing care respond to their care situations. Few studies focus on the roles of both intra- and interpersonal factors in long-term spousal care, particularly in the context of Parkinson's disease (PD). The current study uses longitudinal data over a 10-year period to examine the roles of…

  8. 7 CFR 625.9 - 10-year restoration cost-share agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... restoration cost-share agreements. (a) The restoration plan developed under § 625.13 forms the basis for the... agreement will: (1) Incorporate all portions of a restoration plan; (2) Be for a period of 10 years; (3... implementation of the approved conservation treatment identified in the restoration plan; and (8) Include...

  9. A 10-Year Assessment of Information and Communication Technology Tasks Required in Undergraduate Agriculture Courses

    ERIC Educational Resources Information Center

    Edgar, Leslie D.; Johnson, Donald M.; Cox, Casandra

    2012-01-01

    This study sought to assess required information and communication technology (ICT) tasks in selected undergraduate agriculture courses in a land-grant university during a 10-year period. Selected agriculture faculty members in the fall 1999 (n = 63), 2004 (n = 55), and 2009 (n = 64) semesters were surveyed to determine the ICT tasks they required…

  10. Psychopathy and Offending From Adolescence to Adulthood: A 10-Year Follow-Up

    ERIC Educational Resources Information Center

    Gretton, Heather M.; Hare, Robert D.; Catchpole, Rosalind E. H.

    2004-01-01

    This study examined the predictive validity of the Hare Psychopathy Checklist: Youth Version (PCL:YV; A. E. Forth, D. S. Kosson, & R. D. Hare, 2003) from adolescence to early adulthood. The authors coded the PCL:YV using file information and collected criminal record information over a 10-year follow-up period on 157 boys, ages 12 through 18,…

  11. Prematures with and without Regressed Retinopathy of Prematurity: Comparison of Long-Term (6-10 Years) Ophthalmological Morbidity.

    ERIC Educational Resources Information Center

    Cats, Bernard P.; Tan, Karel E. W. P.

    Reporting long-term ophthalmologic sequelae among ex-prematures at 6 to 10 years of age, this study compares 42 ex-premature infants who had had regressed forms of retinopathy of prematurity (ROP) during the neonatal period with 42 matched non-ROP ex-premature controls at 6 to 10 years of age. Subjects were subdivided into four groups: (1) ROP…

  12. Surrogacy families 10 years on: relationship with the surrogate, decisions over disclosure and children's understanding of their surrogacy origins

    PubMed Central

    Jadva, V.; Blake, L.; Casey, P.; Golombok, S.

    2012-01-01

    BACKGROUND This study aimed to prospectively examine families created using surrogacy over a 10-year period in the UK with respect to intending parents' and children's relationship with the surrogate mother, parents' decisions over disclosure and children's understanding of the nature of their conception. METHODS Semi-structured interviews were administered by trained researchers to intending mothers, intending fathers and children on four occasions over a 10-year period. Forty-two families (19 with a genetic surrogate mother) participated when the child was 1-year old and by age 10 years, 33 families remained in the study. Data were collected on the frequency of contact with the surrogate mother, relationship with the surrogate, disclosure of surrogacy to the child and the child's understanding of their surrogacy birth. RESULTS Frequency of contact between surrogacy families and their surrogate mother decreased over time, particularly for families whose surrogate was a previously unknown genetic carrier (P < 0.001) (i.e. where they had met through a third party and the surrogate mother's egg was used to conceive the child). Most families reported harmonious relationships with their surrogate mother. At age 10 years, 19 (90%) children who had been informed of the nature of their conception had a good understanding of this and 13 of the 14 children who were in contact with their surrogate reported that they liked her. CONCLUSIONS Surrogacy families maintained good relationships with the surrogate mother over time. Children felt positive about their surrogate mother and their surrogacy birth. The sample size of this study was small and further, larger investigations are needed before firm conclusions can be drawn. PMID:22814484

  13. Looking forward, looking back-10 years in urology.

    PubMed

    Albersen, Maarten; Cartwright, Rufus; Choyke, Peter; Goldenberg, S Larry; Goldman, Howard; Lawrentschuk, Nathan; Linehan, W Marston; Murphy, Declan; Nagler, Harris; Scardino, Peter; Shortliffe, Linda; Stenzl, Arnulf; Theodorescu, Dan

    2014-11-01

    When Nature Reviews Urology launched in 2004, the field of urology was vastly different to that which we work in today, and the past 10 years have seen the field change immensely. As a specialty on the forefront of cutting-edge innovation, urologists are often the first to embrace new technologies and ideas. In this Viewpoint, members of the Nature Reviews Urology advisory board were asked what they thought was the most important change, issue or innovation in urology in the past 10 years, and what they expected to be the most important in the next decade. Here are their opinions. PMID:25348169

  14. Looking forward, looking back-10 years in urology.

    PubMed

    Albersen, Maarten; Cartwright, Rufus; Choyke, Peter; Goldenberg, S Larry; Goldman, Howard; Lawrentschuk, Nathan; Linehan, W Marston; Murphy, Declan; Nagler, Harris; Scardino, Peter; Shortliffe, Linda; Stenzl, Arnulf; Theodorescu, Dan

    2014-11-01

    When Nature Reviews Urology launched in 2004, the field of urology was vastly different to that which we work in today, and the past 10 years have seen the field change immensely. As a specialty on the forefront of cutting-edge innovation, urologists are often the first to embrace new technologies and ideas. In this Viewpoint, members of the Nature Reviews Urology advisory board were asked what they thought was the most important change, issue or innovation in urology in the past 10 years, and what they expected to be the most important in the next decade. Here are their opinions.

  15. Endometrial stem/progenitor cells: the first 10 years

    PubMed Central

    Gargett, Caroline E.; Schwab, Kjiana E.; Deane, James A.

    2016-01-01

    BACKGROUND The existence of stem/progenitor cells in the endometrium was postulated many years ago, but the first functional evidence was only published in 2004. The identification of rare epithelial and stromal populations of clonogenic cells in human endometrium has opened an active area of research on endometrial stem/progenitor cells in the subsequent 10 years. METHODS The published literature was searched using the PubMed database with the search terms ‘endometrial stem cells and menstrual blood stem cells' until December 2014. RESULTS Endometrial epithelial stem/progenitor cells have been identified as clonogenic cells in human and as label-retaining or CD44+ cells in mouse endometrium, but their characterization has been modest. In contrast, endometrial mesenchymal stem/stromal cells (MSCs) have been well characterized and show similar properties to bone marrow MSCs. Specific markers for their enrichment have been identified, CD146+PDGFRβ+ (platelet-derived growth factor receptor beta) and SUSD2+ (sushi domain containing-2), which detected their perivascular location and likely pericyte identity in endometrial basalis and functionalis vessels. Transcriptomics and secretomics of SUSD2+ cells confirm their perivascular phenotype. Stromal fibroblasts cultured from endometrial tissue or menstrual blood also have some MSC characteristics and demonstrate broad multilineage differentiation potential for mesodermal, endodermal and ectodermal lineages, indicating their plasticity. Side population (SP) cells are a mixed population, although predominantly vascular cells, which exhibit adult stem cell properties, including tissue reconstitution. There is some evidence that bone marrow cells contribute a small population of endometrial epithelial and stromal cells. The discovery of specific markers for endometrial stem/progenitor cells has enabled the examination of their role in endometrial proliferative disorders, including endometriosis, adenomyosis and Asherman

  16. 10 Years of Media Literacy Education in K-12 Schools

    ERIC Educational Resources Information Center

    Daunic, Rhys

    2011-01-01

    When the author started working with teachers and students on classroom multimedia productions a little over 10 years ago, he had not yet encountered the term "media literacy", nor did he realize he had joined a long standing international movement of media literacy educators. Serendipitous exposure to "old-media" texts by Neil Postman and Noam…

  17. Headshaking in a 10-year-old Thoroughbred mare

    PubMed Central

    2004-01-01

    Abstract A 10-year-old Thoroughbred mare was presented with a 2.5-week history of headshaking. Based on a thorough physical examination, blood analysis, and a fine needle aspirate of an enlarged thyroid gland, a tentative diagnosis of seasonal idiopathic headshaking was made. Treatment with cyproheptadine was attempted. PMID:15025153

  18. Technology for Distance Education: A 10 Year Prospective.

    ERIC Educational Resources Information Center

    Bates, A. W.

    This paper provides an overview of new technologies likely to be widely available within the next 10 years for teaching in Europe. It begins by presenting a framework which draws distinctions between different technologies based on their educational applications, i.e., for teaching or operational purposes, for communicating within or between…

  19. Highlights of 10-Year Remote Sensing Industry Analysis

    NASA Technical Reports Server (NTRS)

    Rabin, Ron

    2002-01-01

    A background and highlights of a 10 year remote sensing industry analysis are provided.Included are the following:Training, educational analysis, staff levels, and end-users analysis, market drivers, market segments,application areas, spatial resolution needs, use of image types.

  20. Duodenal adenocarcinoma in a 10-year-old boy.

    PubMed

    Mohamed, Zouari; Habib, Bouthour; Rabia, Ben Abdallah; Youssef, Hlel; Riath, Ben Malek; Youssef, Gharbi; Nejib, Kaabar

    2014-01-01

    Gastrointestinal malignancies are extremely rare in the paediatric population and duodenal cancers represent an even more unusual entity. It represents 0.3-1% of all gastrointestinal tumours. A case report of a 10-year-old boy with duodenal adenocarcinoma is reported and the difficulties of diagnosing and treating this rare tumour are discussed. PMID:24647303

  1. New actigraphic assessment method for periodic leg movements (PLM).

    PubMed

    Kazenwadel, J; Pollmächer, T; Trenkwalder, C; Oertel, W H; Kohnen, R; Künzel, M; Krüger, H P

    1995-10-01

    A new actigraphic method by which periodic leg movements (PLM) can be measured is presented. Data acquistion and analysis were brought into line to distinguish short-lasting repetive leg movements from random motor restlessness. The definition of PLM follows the generally accepted criteria for PLM scoring. Thirty restless legs patients, all also suffering from PLM, were investigated three times by polysomnography, including tibialis anterior surface electromyography and actigraphy. A high correlation (reliability) was found for the number of PLM per hour spent in bed between the two methods. Furthermore, the actigraph records PLM specifically. An index of random motor restlessness is not sufficient for a reliable PLM according. In addition, periodic movements in sleep (PMS) and PLM show comparable variability in general. The actigraphic assessment of PLM, however, gives a better measure because PMS recordings may result in a substantial underestimation of PLM when sleep efficiency is reduced. This method is an ambulatory assessment tool that can also be used for screening purposes.

  2. [Analysis on characteristics of red tide in Fujian coastal waters during the last 10 years].

    PubMed

    Li, Xue-Ding

    2012-07-01

    There were 161 red tide events collected during the last 10 years from 2001 to 2010 in Fujian coastal waters. Comprehensive analysis was performed using statistical methods and the results indicated the following characteristics of the temporal and spatial distribution of red tide in Fujian coastal waters: (1) Outbreaks of red tide often occurred between April and September, and the peak period was in May and June. Most red tide events lasted for 2 to 4 days, and the affected area was below 50 square kilometers. The first outbreak of red tide tended to occur earlier in recent years, and the lasting time became longer. (2) There were 20 species of organisms causing the red tides in Fujian coastal waters, among which 10 species were Bacillariophyta, 9 species were Dinophyta and 1 species was Protozoa. Prorocentrum donghaiense was the most frequent cause of red tides, followed by Noctiluca scintillans, Skeletonema costatum and Chaetoceros sp.. The species caused red tides obeyed the succession law and there were always new species involved. (2) In terms of spatial distribution, outbreaks of red tides mainly occurred in the coastal waters of Ningde, Fuzhou and Xiamen. The species causing red tides were Prorocentrum donghaiense and Noctiluca in the coastal waters in the north of Pingtan, Fujian Province, Skeletonema costatum and Chaetoceros in the coastal waters in the south of Pingtan, Fujian Province. The comprehensive analysis of the characteristics of red tides during the last 10 years is expected to provide scientific and reasonable basis for the prevention, reduction and forecast of red tides in Fujian coastal waters.

  3. [Analysis on characteristics of red tide in Fujian coastal waters during the last 10 years].

    PubMed

    Li, Xue-Ding

    2012-07-01

    There were 161 red tide events collected during the last 10 years from 2001 to 2010 in Fujian coastal waters. Comprehensive analysis was performed using statistical methods and the results indicated the following characteristics of the temporal and spatial distribution of red tide in Fujian coastal waters: (1) Outbreaks of red tide often occurred between April and September, and the peak period was in May and June. Most red tide events lasted for 2 to 4 days, and the affected area was below 50 square kilometers. The first outbreak of red tide tended to occur earlier in recent years, and the lasting time became longer. (2) There were 20 species of organisms causing the red tides in Fujian coastal waters, among which 10 species were Bacillariophyta, 9 species were Dinophyta and 1 species was Protozoa. Prorocentrum donghaiense was the most frequent cause of red tides, followed by Noctiluca scintillans, Skeletonema costatum and Chaetoceros sp.. The species caused red tides obeyed the succession law and there were always new species involved. (2) In terms of spatial distribution, outbreaks of red tides mainly occurred in the coastal waters of Ningde, Fuzhou and Xiamen. The species causing red tides were Prorocentrum donghaiense and Noctiluca in the coastal waters in the north of Pingtan, Fujian Province, Skeletonema costatum and Chaetoceros in the coastal waters in the south of Pingtan, Fujian Province. The comprehensive analysis of the characteristics of red tides during the last 10 years is expected to provide scientific and reasonable basis for the prevention, reduction and forecast of red tides in Fujian coastal waters. PMID:23002593

  4. Geometric method for forming periodic orbits in the Lorenz system

    NASA Astrophysics Data System (ADS)

    Nicholson, S. B.; Kim, Eun-jin

    2016-04-01

    Many systems in nature are out of equilibrium and irreversible. The non-detailed balance observable representation (NOR) provides a useful methodology for understanding the evolution of such non-equilibrium complex systems, by mapping out the correlation between two states to a metric space where a small distance represents a strong correlation [1]. In this paper, we present the first application of the NOR to a continuous system and demonstrate its utility in controlling chaos. Specifically, we consider the evolution of a continuous system governed by the Lorenz equation and calculate the NOR by following a sufficient number of trajectories. We then show how to control chaos by converting chaotic orbits to periodic orbits by utilizing the NOR. We further discuss the implications of our method for potential applications given the key advantage that this method makes no assumptions of the underlying equations of motion and is thus extremely general.

  5. Primary Nasal Tuberculosis in a 10-Year-Old Girl

    PubMed Central

    Özer, Murat; Özsurekçi, Yasemin; Cengiz, Ali Bülent; Özçelik, Uğur; Yalçın, Ebru; Gököz, Özay

    2016-01-01

    Nasal tuberculosis is a rare clinical entity which mainly presents in elderly people. Nasal tuberculosis has always been considered to be secondary to tuberculosis of the lungs, and in rare instances it is a primary infection, usually when mycobacteria are inhaled. We describe the case of a 10-year-old girl who was successfully treated for primary nasal tuberculosis. This patient is one of the very few children who have been reported to have primary nasal tuberculosis. PMID:27366187

  6. Primary Nasal Tuberculosis in a 10-Year-Old Girl.

    PubMed

    Özer, Murat; Özsurekçi, Yasemin; Cengiz, Ali Bülent; Özçelik, Uğur; Yalçın, Ebru; Gököz, Özay

    2016-01-01

    Nasal tuberculosis is a rare clinical entity which mainly presents in elderly people. Nasal tuberculosis has always been considered to be secondary to tuberculosis of the lungs, and in rare instances it is a primary infection, usually when mycobacteria are inhaled. We describe the case of a 10-year-old girl who was successfully treated for primary nasal tuberculosis. This patient is one of the very few children who have been reported to have primary nasal tuberculosis.

  7. Atypical presentation of macrophagic myofasciitis 10 years post vaccination.

    PubMed

    Ryan, Aisling M; Bermingham, Niamh; Harrington, Hugh J; Keohane, Catherine

    2006-12-01

    Macrophagic myofasciitis (MMF) is an uncommon inflammatory disorder of muscle believed to be due to persistence of vaccine-derived aluminium hydroxide at the site of injection. The condition is characterised by diffuse myalgias, arthralgia and fatigue. We describe a patient with histologically confirmed MMF whose presentation was atypical with left chest and upper limb pain beginning more than 10 years post vaccination. Treatment with steroids led to symptomatic improvement. Although rare, clinicians should consider MMF in cases of atypical myalgia.

  8. Oral maxillofacial neoplasms in an East African population a 10 year retrospective study of 1863 cases using histopathological reports

    PubMed Central

    Kamulegeya, Adriane; Kalyanyama, Boniphace M

    2008-01-01

    Background Neoplasms of the oral maxillofacial area are an interesting entity characterized by differences in nomenclature and classification at different centers. We report neoplastic histopathological diagnoses seen at the departments of oral maxillofacial surgery of Muhimbili and Mulago referral hospitals in Tanzania and Uganda respectively over a 10-year period. Methods We retrieved histopathological reports archived at the departments of oral maxillofacial surgery of Muhimbili and Mulago referral hospitals in Tanzania and Uganda respectively over a 10-year period from June 1989–July 1999. Results In the period between June 1989 and July 1999, 565 and 1298 neoplastic oro-facial cases were retrieved of which 284 (50.53%) and 967 (74.54%) were malignant neoplasms at Muhimbili and Mulago hospitals respectively. Overall 67.28% of the diagnoses recorded were malignant with Kaposi's sarcoma (21.98%), Burkiits lymphoma (20.45%), and squamous cell carcinoma (15.22%) dominating that group while ameloblastoma (9.23%), fibromas (7.3%) and pleomorphic adenoma (4.95%) dominated the benign group. The high frequency of malignancies could be due to inclusion criteria and the clinical practice of selective histopathology investigation. However, it may also be due to higher chances of referrals in case of malignancies. Conclusion There is need to reexamine the slides in these two centers in order to bring them in line with the most recent WHO classification so as to allow for comparison with reports from else where. PMID:18651958

  9. Avian response to bottomland hardwood reforestation: the first 10 years

    USGS Publications Warehouse

    Twedt, D.J.; Wilson, R.R.; Henne-Kerr, J.L.; Grosshuesch, D.A.

    2002-01-01

    Bttomland hardwood forests were planted on agricultural fields in Mississippi and Louisiana using either predominantly Quercus species (oaks) or Populus deltoides (eastern cottonwood). We assessed avian colonization of these reforested sites between 2 and 10 years after planting. Rapid vertical growth of cottonwoods (circa 2 - 3 m / yr) resulted in sites with forest structure that supported greater species richness of breeding birds, increased Shannon diversity indices, and supported greater territory densities than on sites planted with slower-growing oak species. Grassland birds (Spiza americana [Dickcissel], and Sturnella magna [Eastern Meadowlark]) were indicative of species breeding on oak-dominated reforestation # 10 years old. Agelaius phoeniceus (Red-winged Blackbird) and Colinus virginianus (Northern Bobwhite) characterized cottonwood reforestation # 4 years old, whereas 14 species of shrub-scrub birds (e.g., Passerina cyanea [Indigo Bunting]) and early-successional forest birds (e.g., Vireo gilvus [Warbling Vireo]) typified cottonwood reforestation 5 to 9 years after planting. Rates of daily nest survival did not differ between reforestation strategies. Nest parasitism increased markedly in older cottonwood stands, but was overwhelmed by predation as a cause of nest failure. Based on Partners in Flight prioritization scores and territory densities, the value of cottonwood reforestation for avian conservation was significantly greater than that of oak reforestation during their first 10 years. Because of benefits conferred on breeding birds, we recommend reforestation of bottomland hardwoods include a high proportion of fast-growing, early successional species such as cottonwood.

  10. MMI's Metadata and Vocabulary Solutions: 10 Years and Growing

    NASA Astrophysics Data System (ADS)

    Graybeal, J.; Gayanilo, F.; Rueda-Velasquez, C. A.

    2014-12-01

    The Marine Metadata Interoperability project (http://marinemetadata.org) held its public opening at AGU's 2004 Fall Meeting. For 10 years since that debut, the MMI guidance and vocabulary sites have served over 100,000 visitors, with 525 community members and continuous Steering Committee leadership. Originally funded by the National Science Foundation, over the years multiple organizations have supported the MMI mission: "Our goal is to support collaborative research in the marine science domain, by simplifying the incredibly complex world of metadata into specific, straightforward guidance. MMI encourages scientists and data managers at all levels to apply good metadata practices from the start of a project, by providing the best guidance and resources for data management, and developing advanced metadata tools and services needed by the community." Now hosted by the Harte Research Institute at Texas A&M University at Corpus Christi, MMI continues to provide guidance and services to the community, and is planning for marine science and technology needs for the next 10 years. In this presentation we will highlight our major accomplishments, describe our recent achievements and imminent goals, and propose a vision for improving marine data interoperability for the next 10 years, including Ontology Registry and Repository (http://mmisw.org/orr) advancements and applications (http://mmisw.org/cfsn).

  11. Periodic local MP2 method employing orbital specific virtuals

    SciTech Connect

    Usvyat, Denis Schütz, Martin; Maschio, Lorenzo

    2015-09-14

    We introduce orbital specific virtuals (OSVs) to represent the truncated pair-specific virtual space in periodic local Møller-Plesset perturbation theory of second order (LMP2). The OSVs are constructed by diagonalization of the LMP2 amplitude matrices which correspond to diagonal Wannier-function (WF) pairs. Only a subset of these OSVs is adopted for the subsequent OSV-LMP2 calculation, namely, those with largest contribution to the diagonal pair correlation energy and with the accumulated value of these contributions reaching a certain accuracy. The virtual space for a general (non diagonal) pair is spanned by the union of the two OSV sets related to the individual WFs of the pair. In the periodic LMP2 method, the diagonal LMP2 amplitude matrices needed for the construction of the OSVs are calculated in the basis of projected atomic orbitals (PAOs), employing very large PAO domains. It turns out that the OSVs are excellent to describe short range correlation, yet less appropriate for long range van der Waals correlation. In order to compensate for this bias towards short range correlation, we augment the virtual space spanned by the OSVs by the most diffuse PAOs of the corresponding minimal PAO domain. The Fock and overlap matrices in OSV basis are constructed in the reciprocal space. The 4-index electron repulsion integrals are calculated by local density fitting and, for distant pairs, via multipole approximation. New procedures for determining the fit-domains and the distant-pair lists, leading to higher efficiency in the 4-index integral evaluation, have been implemented. Generally, and in contrast to our previous PAO based periodic LMP2 method, the OSV-LMP2 method does not require anymore great care in the specification of the individual domains (to get a balanced description when calculating energy differences) and is in that sense a black box procedure. Discontinuities in potential energy surfaces, which may occur for PAO-based calculations if one is not

  12. Periodic local MP2 method employing orbital specific virtuals.

    PubMed

    Usvyat, Denis; Maschio, Lorenzo; Schütz, Martin

    2015-09-14

    We introduce orbital specific virtuals (OSVs) to represent the truncated pair-specific virtual space in periodic local Møller-Plesset perturbation theory of second order (LMP2). The OSVs are constructed by diagonalization of the LMP2 amplitude matrices which correspond to diagonal Wannier-function (WF) pairs. Only a subset of these OSVs is adopted for the subsequent OSV-LMP2 calculation, namely, those with largest contribution to the diagonal pair correlation energy and with the accumulated value of these contributions reaching a certain accuracy. The virtual space for a general (non diagonal) pair is spanned by the union of the two OSV sets related to the individual WFs of the pair. In the periodic LMP2 method, the diagonal LMP2 amplitude matrices needed for the construction of the OSVs are calculated in the basis of projected atomic orbitals (PAOs), employing very large PAO domains. It turns out that the OSVs are excellent to describe short range correlation, yet less appropriate for long range van der Waals correlation. In order to compensate for this bias towards short range correlation, we augment the virtual space spanned by the OSVs by the most diffuse PAOs of the corresponding minimal PAO domain. The Fock and overlap matrices in OSV basis are constructed in the reciprocal space. The 4-index electron repulsion integrals are calculated by local density fitting and, for distant pairs, via multipole approximation. New procedures for determining the fit-domains and the distant-pair lists, leading to higher efficiency in the 4-index integral evaluation, have been implemented. Generally, and in contrast to our previous PAO based periodic LMP2 method, the OSV-LMP2 method does not require anymore great care in the specification of the individual domains (to get a balanced description when calculating energy differences) and is in that sense a black box procedure. Discontinuities in potential energy surfaces, which may occur for PAO-based calculations if one is not

  13. Periodic local MP2 method employing orbital specific virtuals.

    PubMed

    Usvyat, Denis; Maschio, Lorenzo; Schütz, Martin

    2015-09-14

    We introduce orbital specific virtuals (OSVs) to represent the truncated pair-specific virtual space in periodic local Møller-Plesset perturbation theory of second order (LMP2). The OSVs are constructed by diagonalization of the LMP2 amplitude matrices which correspond to diagonal Wannier-function (WF) pairs. Only a subset of these OSVs is adopted for the subsequent OSV-LMP2 calculation, namely, those with largest contribution to the diagonal pair correlation energy and with the accumulated value of these contributions reaching a certain accuracy. The virtual space for a general (non diagonal) pair is spanned by the union of the two OSV sets related to the individual WFs of the pair. In the periodic LMP2 method, the diagonal LMP2 amplitude matrices needed for the construction of the OSVs are calculated in the basis of projected atomic orbitals (PAOs), employing very large PAO domains. It turns out that the OSVs are excellent to describe short range correlation, yet less appropriate for long range van der Waals correlation. In order to compensate for this bias towards short range correlation, we augment the virtual space spanned by the OSVs by the most diffuse PAOs of the corresponding minimal PAO domain. The Fock and overlap matrices in OSV basis are constructed in the reciprocal space. The 4-index electron repulsion integrals are calculated by local density fitting and, for distant pairs, via multipole approximation. New procedures for determining the fit-domains and the distant-pair lists, leading to higher efficiency in the 4-index integral evaluation, have been implemented. Generally, and in contrast to our previous PAO based periodic LMP2 method, the OSV-LMP2 method does not require anymore great care in the specification of the individual domains (to get a balanced description when calculating energy differences) and is in that sense a black box procedure. Discontinuities in potential energy surfaces, which may occur for PAO-based calculations if one is not

  14. 10-year clinical evaluation of a self-etching adhesive system.

    PubMed

    Akimoto, Naotake; Takamizu, Masaaki; Momoi, Yasuko

    2007-01-01

    This study evaluated the long-term clinical performance of a self-etching adhesive system, Clearfil Liner Bond 2. Two operators placed a total of 87 restorations among 42 patients. Carious dentin was identified with the help of Caries Detector and was removed using only a low speed round bur. Clearfil Liner Bond 2 was applied following the manufacturer's directions, and the resin composite was then placed. The number of restorations placed by cavity classification were: 8-Class I, 11-Class II, 21-Class III, 2-Class IV and 45-Class V. The restorations were evaluated in 5 categories according to modified USPHS criteria: pulpal response, marginal integrity, marginal discoloration, retention and secondary caries. Assessments were done at baseline, immediately after placement and at 6-months and 1, 5, 7 and 10 years. Recall rates at each assessment period were 83.9% (6-months), 82.8% (1 year), 59.8% (5 years), 77.0% (7 years) and 50.6% (10 years). In terms of assessment categories, there were no recorded sensitivity, retention loss or secondary caries at any of the five recall periods. At the 10-year assessment, 40 out of 44 restorations (90.9%) were rated Bravo for marginal integrity and 39 restorations (88.6%) were rated Bravo for marginal discoloration (Wilcoxon signed-ranks test p < 0.05). This data demonstrates the retention rate and pulpal response of the self-etching adhesive system Clearfil Liner Bond 2 was excellent at 10 years. Most cases showed slight marginal changes during clinical function; however, these changes were not clinically severe by USPHS criteria. These data demonstrate that placement of the Clearfil Liner Bond 2 self-etching adhesive system was demonstrated to be acceptable for the clinical restoration of human teeth following 10 years of clinical function.

  15. Developing of 10-year EEZ seafloor mapping and research program

    USGS Publications Warehouse

    Lockwood, M.; Hill, G.W.

    1988-01-01

    The intent of expanding the exploration already begun on the outer continental shelf to the frontier of the EEZ (Exclusive Economic Zone) is to determine the "characteristics' and resource potential of this region. To coordinate this exploration, a Joint Office for Mapping and Research (JOMAR) has been established by the US Geological Survey (in the Department of the Interior) and the National Oceanic and Atmospheric Administration (in the Department of Commerce). JOMAR's main purpose is to help direct and coordinate ongoing and planned seafloor related activities in the EEZ and prepare a 10-year plan for mapping and research. -from Authors

  16. Motor Speech Disorders: Where Will We Be in 10 Years?

    PubMed

    Duffy, Joseph R

    2016-08-01

    Research and practice in the area of motor speech disorders (MSDs) will change in the next 10 years, most likely in evolutionary rather revolutionary ways. We are likely to see an increase in the understanding of the underpinnings of MSDs and refinements in assessment and diagnosis. Management approaches probably will be refined, as will how outcomes are measured. The evidence base for treatment efficacy will grow. Technology and changes in the health care system will have strong and overarching, but not easily predicted, influences. This article provides a broad overview of these and related issues, with some cautious predictions. PMID:27232096

  17. Recurrent renal cell cancer: 10 years or more after nephrectomy.

    PubMed

    Abara, Emmanuel; Chivulescu, Iolanda; Clerk, Nilam; Cano, Pablo; Goth, Alexis

    2010-04-01

    Localized renal cell carcinoma (RCC) responds well to surgery. Patients often question how long they have to be on surveillance after their surgery. Several follow-up patterns have been described in the literature. Until 2009, no published established Canadian guidelines existed to assist Canadian health-care practitioners in the surveillance of these patients. We present 3 cases of RCC that recurred 10 years or longer after the initial nephrectomy. These cases emphasize the need for careful long-term follow-up, as recommended in the Canadian Urological Association guidelines. We also discuss the optimism of prolonged disease survival in the era of novel therapeutic agents that target angiogenesis. PMID:20368882

  18. 10-year update of Stirling cryogenic coolers in France

    NASA Astrophysics Data System (ADS)

    Martin, Jean-Yves

    2000-12-01

    This paper enters in the scope of the session on 10-year update of IR in France. Cryotechnologies is a leader in both the French and European markets as a designer and manufacturer of cryogenic coolers. Serial production of the first generation of Stirling cryocoolers started at Cryotechnologies in the late eighties. A range of integral Stirling coolers is nowadays available and completes the existing range of split Stirling cryocoolers. Technical improvements are keeping up with the market evolutions and new potential applications (costs reduction, fast cooldown time, increase of cooling power, very high reliability, pulse tube cold finger).

  19. Hepatitis C virus recurrence after liver transplantation: A 10-year evaluation

    PubMed Central

    Gitto, Stefano; Belli, Luca Saverio; Vukotic, Ranka; Lorenzini, Stefania; Airoldi, Aldo; Cicero, Arrigo Francesco Giuseppe; Vangeli, Marcello; Brodosi, Lucia; Panno, Arianna Martello; Di Donato, Roberto; Cescon, Matteo; Grazi, Gian Luca; De Carlis, Luciano; Pinna, Antonio Daniele; Bernardi, Mauro; Andreone, Pietro

    2015-01-01

    AIM: To evaluate the predictors of 10-year survival of patients with hepatitis C recurrence. METHODS: Data from 358 patients transplanted between 1989 and 2010 in two Italian transplant centers and with evidence of hepatitis C recurrence were analyzed. A χ2, Fisher’s exact test and Kruskal Wallis’ test were used for categorical and continuous variables, respectively. Survival analysis was performed at 10 years after transplant using the Kaplan-Meier method, and a log-rank test was used to compare groups. A P level less than 0.05 was considered significant for all tests. Multivariate analysis of the predictive role of different variables on 10-year survival was performed by a stepwise Cox logistic regression. RESULTS: The ten-year survival of the entire population was 61.2%. Five groups of patients were identified according to the virological response or lack of a response to antiviral treatment and, among those who were not treated, according to the clinical status (mild hepatitis C recurrence, “too sick to be treated” and patients with comorbidities contraindicating the treatment). While the 10-year survival of treated and untreated patients was not different (59.1% vs 64.7%, P = 0.192), patients with a sustained virological response had a higher 10-year survival rate than both the “non-responders” (84.7% vs 39.8%, P < 0.0001) and too sick to be treated (84.7% vs 0%, P < 0.0001). Sustained virological responders had a survival rate comparable to patients untreated with mild recurrence (84.7% vs 89.3%). A sustained virological response and young donor age were independent predictors of 10-year survival. CONCLUSION: Sustained virological response significantly increased long-term survival. Awaiting the interferon-free regimen global availability, antiviral treatment might be questionable in selected subjects with mild hepatitis C recurrence. PMID:25852276

  20. Is the Party Over? Cannabis and Juvenile Psychiatric Disorder: The Past 10 Years

    ERIC Educational Resources Information Center

    Rey, Joseph M.; Martin, Andres; Krabman, Peter

    2004-01-01

    Objective: To critically review cannabis research during the past 10 years in relation to rates of use, behavioral problems, and mental disorders in young people. Method: Studies published in English between 1994 and 2004 were identified through systematic searches of literature databases. The material was selectively reviewed focusing on child…

  1. Psychiatric Aspects of Child and Adolescent Obesity: A Review of the Past 10 Years

    ERIC Educational Resources Information Center

    Zametkin, Alan J.; Zoon, Christine K.; Klein, Hannah W.; Munson, Suzanne

    2004-01-01

    Objective: To review the past 10 years of published research on psychiatric aspects of child and adolescent obesity and highlight information mental health professionals need for preventing obesity in youths and diagnosing and treating it. Method: Researchers performed computerized and manual searches of the literature and summarized the most…

  2. Childhood Reactions to Terrorism-Induced Trauma: A Review of the Past 10 Years

    ERIC Educational Resources Information Center

    Fremont, Wanda P.

    2004-01-01

    Objective: To summarize the literature about the clinical presentation and treatment interventions of childhood reactions to terrorism-induced trauma. Method: The literature on children's responses to terrorist activities was reviewed. Results: Over the past 10 years, more research has emerged on the subject of terrorism in children. Many of the…

  3. Citations to Australian Astronomy: 5- and 10-Year Benchmarks

    NASA Astrophysics Data System (ADS)

    Kenyon, Katherine H.; Paramasivam, Arjun; Tu, Jiachin; Zhang, Albert; Graham, Alister W.

    2012-03-01

    Expanding upon Pimbblet's 2011 analysis of career h-indices for members of the Astronomical Society of Australia, we provide additional citation metrics which are geared to quantifying the current performance of all professional astronomers in Australia. We have trawled the staff web-pages of Australian Universities, Observatories and Research Organisations hosting professional astronomers, and identified 384 PhD-qualified, research-active, astronomers in the nation. 132 of these are not members of the Astronomical Society of Australia. Using the SAO/NASA Astrophysics Data System, we provide the three following common metrics based on publications in the first decade of the 21st century (2001-2010): h-index, author-normalised citation count and lead-author citation count. We additionally present a somewhat more inclusive analysis, applicable for many early-career researchers, that is based on publications from 2006-2010. Histograms and percentiles, plus top-performer lists, are presented for each category. Finally, building on Hirsch's empirical equation, we find that the (10-year) h-index and (10-year) total citation count T can be approximated by the relation AS12011_IE1.gif for h>~5.

  4. Bacterial nanocellulose production and application: a 10-year overview.

    PubMed

    Jozala, Angela Faustino; de Lencastre-Novaes, Leticia Celia; Lopes, André Moreni; de Carvalho Santos-Ebinuma, Valéria; Mazzola, Priscila Gava; Pessoa-Jr, Adalberto; Grotto, Denise; Gerenutti, Marli; Chaud, Marco Vinicius

    2016-03-01

    Production of bacterial nanocellulose (BNC) is becoming increasingly popular owing to its environmentally friendly properties. Based on this benefit of BNC production, researchers have also begun to examine the capacity for cellulose production through microbial hosts. Indeed, several research groups have developed processes for BNC production, and many studies have been published to date, with the goal of developing methods for large-scale production. During BNC bioproduction, the culture medium represents approximately 30 % of the total cost. Therefore, one important and challenging aspect of the fermentation process is identification of a new cost-effective culture medium that can facilitate the production of high yields within short periods of time, thereby improving BNC production and permitting application of BNC in the biotechnological, medical, pharmaceutical, and food industries. In this review, we addressed different aspects of BNC production, including types of fermentation processes and culture media, with the aim of demonstrating the importance of these parameters. PMID:26743657

  5. Characteristics of Primary Cutaneous T-Cell Lymphoma in Iran: A 10-Year Retrospective Study

    PubMed Central

    Fatemi Naeini, Farahnaz; Sadeghiyan, Hamidreza; Pourazizi, Mohsen; Najafian, Jamshid; Abtahi-Naeini, Bahareh

    2014-01-01

    Background. Primary cutaneous T-cell lymphomas (CTCLs) are a group of extranodal non-Hodgkin lymphomas that may be present in the skin without any evidence of extracutaneous disease. The aim of this study was to evaluate the epidemiological characteristics of primary CTCL in Isfahan, Iran. Method. A total of 95 patients who were diagnosed as having primary CTCL were recruited during a 10-year period (2003–2013) and were classified according to the new WHO-EORTC criteria. Results. The patient group consisted of 43 (44.8%) males and 53 (55.2%) females, which indicated a female predominance (M : F ratio 1 : 1.2). The mean age at the time of diagnosis was 41.78 ± 16.88 years (range: 7–84 years). Prior to diagnosis, the lesions had persisted for a mean of 8.34 ± 4.38 years (range: 0–55 years). The age at peak diagnosis was 20–40 years (43%). The most frequent subtypes were mycosis fungoides (MF) (88.5%). Four patients died from CTCL-related complications. Conclusions. The distinguishing epidemiologic characteristics of primary CTCL, particularly those MF, in Iran, are the absence of a male predominance and lower age at diagnosis. This is likely because of the characteristic ethnic group diversity and increased susceptibility among younger population. PMID:27437467

  6. The Ecology of Sustainable Implementation: Reflection on a 10-Year Case History Illustration.

    PubMed

    Rimehaug, Tormod

    2014-01-01

    The primary aim of this paper is to illustrate the strategic and ecological nature of implementation. The ultimate aim of implementation is not dissemination but sustainability beyond the implementation effort. A case study is utilized to illustrate these broad and long-term perspectives of sustainable implementation based on qualitative analyses of a 10-year implementation effort. The purveyors aimed to develop selective community prevention services for children in families burdened by parental psychiatric or addictive problems. Services were gradually disseminated to 23 sites serving 40 municipalities by 2013. Up to 2013, only one site terminated services after initial implementation. Although many sites suspended services for shorter periods, services are still offered at 22 sites. This case analysis is based on project reports, user evaluations, practitioner interviews, and service statistics. The paper focuses on the analyses and strategies utilized to cope with quality decay and setbacks as well as progress and success in disseminating and sustaining the services and their quality. Low-cost multilevel strategies to implement services at the community level were organized by a prevention unit in child psychiatry, supervised by a university department (purveyors). The purveyors were also involved in national and international collaboration and development. Multilevel strategies included manualized intervention, in-practice training methods, organizational responsibility, media strategies, service evaluation, staff motivation maintenance, quality assurance, and proposals for new law regulations. These case history aspects will be discussed in relation to the implementation literature, focusing on possible applicability across settings.

  7. The 10-year Course of PTSD in Borderline Patients and Axis II Comparison Subjects

    PubMed Central

    Zanarini, Mary C.; Hörz, Susanne; Frankenburg, Frances R.; Weingeroff, Jolie; Reich, D. Bradford; Fitzmaurice, Garrett

    2011-01-01

    Objective The first objective is to detail the prevalence of PTSD over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD and the third is to assess the relationship between sexual adversity and the likelihood of remission and recurrence of PTSD. Method The SCID I was administered to 290 borderline inpatients and 72 axis II comparison subjects during their index admission and re-administered at five contiguous two-year follow-up periods. Results The prevalence of PTSD declined significantly over time for patients with BPD (61%). Over 85% of borderline patients meeting criteria for PTSD at baseline experienced a remission by the time of the 10-year follow-up. Recurrences (40%) and new onsets (27%) were less common. A childhood history of sexual abuse significantly decreased the likelihood of remission from PTSD and an adult history of sexual assault significantly increased the likelihood of a recurrence of PTSD. Conclusion Taken together, the results of this study suggest that PTSD is not a chronic disorder for the majority of borderline patients. They also suggest a strong relationship between sexual adversity and the course of PTSD among patients with BPD. PMID:21564040

  8. Newspaper Coverage of Autism Treatment in Canada: 10-Year Trends (2004–2013)

    PubMed Central

    Lanovaz, Marc J; Dufour, Marie-Michèle; Shah, Shalaka

    2015-01-01

    Objective: To compare trends in coverage of empirically supported and alternative autism treatments in Canadian newspapers during a 10-year period and to examine whether the portrayal of empirically supported and alternative treatments differed. Method: We searched a sample of 10 daily local and national Canadian newspapers using the word autism combined with intervention or treatment in the Proquest Canadian Newsstand and Eureka.cc databases, which yielded a total of 857 articles published between 2004 and 2013. In our subsequent analyses, we only included articles whose main topic was autism and that referred to at least one treatment. We then categorized the 137 remaining articles by treatment and rated whether each treatment category was portrayed in a favourable, unfavourable, or neutral manner. Results: In total, 46% of the articles discussed at least 1 empirically supported treatment, 53% at least 1 alternative treatment, and 12% at least 1 uncategorized treatment. Newspaper articles provided favourable, unfavourable, and neutral portrayals of empirically supported treatments in 75%, 10%, and 16% of cases, respectively. In contrast, alternative treatments were portrayed favourably in 52%, unfavourably in 32%, and neutrally in 16% of cases. Our analyses indicated that empirically supported treatments were portrayed more favourably than alternative treatments (χ2 = 10.42, df = 2, P = 0.005). Conclusions: Despite some encouraging trends, our study has shown that researchers and clinicians must continue to clarify misconceptions about autism treatment. Families of people with autism spectrum disorders should be directed toward more reliable and accurate sources of information. PMID:26175392

  9. Parathyroid Carcinoma in a 10 Years Old Female Child.

    PubMed

    Rahman, M M; Karim, S S; Joarder, A I; Mubin, S; Abir, M M; Morshed, M S

    2015-07-01

    Parathyroid carcinoma (PC) is a rare cause of hypercalcaemia in children. Only 7 cases of PC have been reported so far in the world journal. The authors report the 8th case of parathyroid carcinoma in children less than 16 years of age. A 10 year old girl presented with difficulty in walking, dorsiflexion and ulnar deviation of both wrist joints and occasional pain in the central abdomen of about two years duration. Biochemical investigations revealed serum calcium 12.2 mg/dL (normal 9-11 mg/dL), serum alkaline phosphate 4992 U/L (normal 50-136 U/L), PTH (parathyroid hormone) 2217 pg/ml (normal 9-80 pg/ml). Parathyroid scintigraphy localized the lesion in the left parathyroid gland. X-ray showed bilateral coxa vera, genu valgus deformity and multiple stress fractures in both wrist joints. Histopathology confirmed PC with capsular and vascular invasion.

  10. Seismological network in China celebrates first 10 years

    NASA Astrophysics Data System (ADS)

    Chen, Y. T.; Zhou, G. W.; Wu, Z. L.

    Located near the boundary of the India, Pacific, and Eurasia plates, the Chinese continent is characterized by complex tectonics and high seismicity. Since the Sino-U.S. cooperative China Digital Seismograph Network (CDSN) began operating 10 years ago, it has played an active role in studying the seismology of China.Studies of the lithospheric structure and earthquake sources using digital seismic data are highly important in the study of geodynamics and the reduction of seismic disasters. Using the CDSN data, extensive studies were carried out by seismologists both in China and abroad. The studies investigated the lithospheric structure, seismic anisotropy within the upper mantle, and inversion of regional centroid moment tensors (RCMTs) of moderate to strong earthquakes. Earthquake sources were imaged based on broadband digital waveform analysis. As a result, over 100 papers have been published in China and abroad since 1990.

  11. Class III treatment using facial mask: Stability after 10 years

    PubMed Central

    Ramos, Adilson Luiz

    2014-01-01

    Early Class III malocclusion treatment may not have long-term stability due to mandibular growth. Although some features of this malocclusion point to a better prognosis, it is practically impossible for the orthodontist to foresee cases that require new intervention. Many patients need retreatment, whether compensatory or orthodontic-surgical. The present study reports the case of a Class III patient treated at the end of the mixed dentition with the use of a face mask followed by conventional fixed appliances. The case remains stable 10 years after treatment completion. It was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as a requirement for the title of certified by the BBO. PMID:25715726

  12. Class III treatment using facial mask: stability after 10 years.

    PubMed

    Ramos, Adilson Luiz

    2014-01-01

    Early Class III malocclusion treatment may not have long-term stability due to mandibular growth. Although some features of this malocclusion point to a better prognosis, it is practically impossible for the orthodontist to foresee cases that require new intervention. Many patients need retreatment, whether compensatory or orthodontic-surgical. The present study reports the case of a Class III patient treated at the end of the mixed dentition with the use of a face mask followed by conventional fixed appliances. The case remains stable 10 years after treatment completion. It was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as a requirement for the title of certified by the BBO.

  13. Scurvy in a 10-year-old boy.

    PubMed

    Cole, John A; Warthan, Molly M; Hirano, Stefanie A; Gowen, Clarence W; Williams, Judith V

    2011-01-01

    Scurvy, or hypovitaminosis C, is an uncommon condition that exists today primarily within certain unique populations-particularly the elderly subjects, patients with neurodevelopmental disabilities or psychiatric illnesses, or others with unusual dietary habits. Vitamin C is an essential nutrient in the human body, and is important in synthesizing collagen factor whose faulty production is responsible for most of the clinical manifestations of scurvy. These clinical manifestations can include dystrophic or corkscrew hairs, gingival hyperplasia, and weakened blood vessel walls, causing bleeding in the skin, joints, and other organs. Although rare in the Unites States, the presence of scurvy should not be forgotten because of its presence among susceptible populations. Moreover, with its diagnosis, treatment and cure is one of the simplest in modern medicine. We report a case of scurvy in a 10-year-old autistic child.

  14. New Jersey 10-year energy plan urges cogeneration reliance

    SciTech Connect

    Barber, J.

    1985-03-25

    The New Jersey DOE has drafted a 10-year master plan aimed at expanding state-wide conservation measures and encouraging the development of more than 2000 MW of cogenerated electricity through a combination of tax incentive and financial assistance programs. Although the plan deals with all sectors of energy use, the focus is on reducing industrial fuel and power costs. The incentives include a five-year exemption of new cogeneration facilities from property taxes, new buy-back rates equal to full avoided costs, and utility tariffs that allow the wheeling of cogenerated power. Part of the relicensing of casino-hotels could be a requirement for investigating the feasibility of installing a cogeneration system.

  15. The Troubling Trichotomy 10 Years Later: Where Are We Now?

    PubMed

    Barrocas, Albert

    2016-06-01

    A decade ago, "Nutrition Support and The Troubling Trichotomy: A Call To Action" was published in this journal, identifying existing conflicts among technological, ethical, and legal aspects of nutrition support therapy, particularly in terminal or end-of-life situations. Over the past 10 years, the American Society for Parenteral and Enteral Nutrition and others have responded to the action call. A "state of the trichotomy" reveals that while much has been achieved, differences in all 3 aspects will continue to exist due to their dynamic and ever-changing states. The technology arena has made it possible to increase the delivery of nutrition support in alternative settings with the use of telemedicine and social media. Critical/crucial conversations and earlier declarations of individual wishes for care and treatment while having decision-making capacity have been enhanced with the focus on patient-centered and family-centered care. The definition of death as brain death has been challenged in at least one instance. Conflicts between the state's interests and the individual's interests have added to recent legal controversies. Notwithstanding the progress made over the past 10 years, several challenges remain. The future challenges presented by the Troubling Trichotomy can be best confronted if we ACT-Accountability, Communication, and Teamwork. The focus of teamwork should move from multidisciplinary and interdisciplinary teams to transdisciplinary teams, reflecting the shift to function rather than form presented by the new healthcare environment. The transdisciplinary team will be able address the opportunities of the Troubling Trichotomy in the next decade by incorporating the 12 Cs, as detailed in the article.

  16. The Troubling Trichotomy 10 Years Later: Where Are We Now?

    PubMed

    Barrocas, Albert

    2016-06-01

    A decade ago, "Nutrition Support and The Troubling Trichotomy: A Call To Action" was published in this journal, identifying existing conflicts among technological, ethical, and legal aspects of nutrition support therapy, particularly in terminal or end-of-life situations. Over the past 10 years, the American Society for Parenteral and Enteral Nutrition and others have responded to the action call. A "state of the trichotomy" reveals that while much has been achieved, differences in all 3 aspects will continue to exist due to their dynamic and ever-changing states. The technology arena has made it possible to increase the delivery of nutrition support in alternative settings with the use of telemedicine and social media. Critical/crucial conversations and earlier declarations of individual wishes for care and treatment while having decision-making capacity have been enhanced with the focus on patient-centered and family-centered care. The definition of death as brain death has been challenged in at least one instance. Conflicts between the state's interests and the individual's interests have added to recent legal controversies. Notwithstanding the progress made over the past 10 years, several challenges remain. The future challenges presented by the Troubling Trichotomy can be best confronted if we ACT-Accountability, Communication, and Teamwork. The focus of teamwork should move from multidisciplinary and interdisciplinary teams to transdisciplinary teams, reflecting the shift to function rather than form presented by the new healthcare environment. The transdisciplinary team will be able address the opportunities of the Troubling Trichotomy in the next decade by incorporating the 12 Cs, as detailed in the article. PMID:26941110

  17. Outcomes of combined phacoemulsification and deep sclerectomy: a 10-year UK single-centre study

    PubMed Central

    Mercieca, K; Shevade, B; Anand, N

    2015-01-01

    Purpose To report the outcomes of combined phacoemulsification and -deep sclerectomy (phaco-DS) from a single UK centre over a 10-year period. Methods Retrospective analysis of phaco-DS data extracted from an ongoing glaucoma surgery database within Calderdale and Huddersfield NHS Trust. Two hundred and ninety-six eyes of 282 patients were included. Data included patient demographics, pre- and postoperative intraocular pressure (IOP), use of mitomycin C (MMC), spacer device implantation, and follow-up details including surgical success rates. IOP success criteria were: (A) IOP <19 mm Hg and/or 20% decrease from baseline and (B) IOP <16 mm Hg and/or 30% drop from baseline. Results Mean follow-up was 63.5±35.3 months. MMC was applied in 145 eyes (49%). Kaplan–Meier success rates in all eyes for criteria A were 89.1% and 80% with glaucoma medications (qualified success) and 81.2% and 68.3% without medications (unqualified success) at 2 and 5 years, respectively. Qualified success for criteria B was 72.4 and 61.4% and unqualified rates were 67.2 and 55.2% for the same time periods. Repeated-measures ANOVA showed significantly lower IOP in the phaco-DS with MMC group up to 3 years postoperatively (P=0.002). Cox's proportional hazards for criteria B, however, showed no significant effect of MMC application in the long term (P=0.2). Increasing age and laser goniopuncture were positively associated with success, whereas the absence of spacer devices was negatively associated. At last follow-up, 20% of eyes were on glaucoma medications. Complication rates were low with hypotony rates of 0.68%. Conclusions This study confirms the long-term safety and efficacy of phaco-DS as a primary glaucoma procedure. PMID:26337945

  18. Stress Generation, Avoidance Coping, and Depressive Symptoms: A 10-Year Model

    PubMed Central

    Holahan, Charles J.; Moos, Rudolf H.; Holahan, Carole K.; Brennan, Penny L.; Schutte, Kathleen K.

    2011-01-01

    This study examined (a) the role of avoidance coping in prospectively generating both chronic and acute life stressors and (b) the stress-generating role of avoidance coping as a prospective link to future depressive symptoms. Participants were 1,211 late-middle-aged individuals (500 women and 711 men) assessed 3 times over a 10-year period. As predicted, baseline avoidance coping was prospectively associated with both more chronic and more acute life stressors 4 years later. Furthermore, as predicted, these intervening life stressors linked baseline avoidance coping and depressive symptoms 10 years later, controlling for the influence of initial depressive symptoms. These findings broaden knowledge about the stress-generation process and elucidate a key mechanism through which avoidance coping is linked to depressive symptoms. PMID:16173853

  19. Rugby injuries to the cervical spine and spinal cord: a 10-year review.

    PubMed

    Scher, A T

    1998-01-01

    A 10-year review (1987-1996) of injuries sustained to the spine and spinal cord in rugby players with resultant paralysis has been undertaken. This article reviews that the incidence of serious rugby spine and spinal cord injuries in South Africa has increased over the 10-year period reviewed, despite stringent new rules instituted in an attempt to decrease the incidence of these injuries. The mechanisms of injury, as previously reported, remain the same as well as the phases of game responsible for injury of the tight scrum, tackle, rucks, and mauls. Two new observations are reported: the first is related to the occurrence of spinal cord concussion with transient paralysis, and the second is related to the increased incidence of osteoarthritis of the cervical spine in rugby players. PMID:9475983

  20. Physical aggression, compromised social support, and 10-year marital outcomes: Testing a relational spillover model.

    PubMed

    Sullivan, Kieran T; Pasch, Lauri A; Lawrence, Erika; Bradbury, Thomas N

    2015-12-01

    The purpose of the present study was to test a relational spillover model of physical aggression whereby physical aggression affects marital outcomes due to its effects on how spouses ask for and provide support to one another. Newlywed couples (n = 172) reported levels of physical aggression over the past year and engaged in interactions designed to elicit social support; marital adjustment, and stability were assessed periodically over the first 10 years of marriage. Multilevel modeling revealed that negative support behavior mediated the relationship between physical aggression and 10-year marital adjustment levels whereas positive support behavior mediated the relationship between physical aggression and divorce status. These findings emphasize the need to look beyond conflict when explaining how aggression affects relationships and when working with couples with a history of physical aggression who are seeking to improve their relationships.

  1. Physical aggression, compromised social support, and 10-year marital outcomes: Testing a relational spillover model.

    PubMed

    Sullivan, Kieran T; Pasch, Lauri A; Lawrence, Erika; Bradbury, Thomas N

    2015-12-01

    The purpose of the present study was to test a relational spillover model of physical aggression whereby physical aggression affects marital outcomes due to its effects on how spouses ask for and provide support to one another. Newlywed couples (n = 172) reported levels of physical aggression over the past year and engaged in interactions designed to elicit social support; marital adjustment, and stability were assessed periodically over the first 10 years of marriage. Multilevel modeling revealed that negative support behavior mediated the relationship between physical aggression and 10-year marital adjustment levels whereas positive support behavior mediated the relationship between physical aggression and divorce status. These findings emphasize the need to look beyond conflict when explaining how aggression affects relationships and when working with couples with a history of physical aggression who are seeking to improve their relationships. PMID:26168263

  2. ESO and Chile: 10 Years of Productive Scientific Collaboration

    NASA Astrophysics Data System (ADS)

    2006-06-01

    ESO and the Government of Chile launched today the book "10 Years Exploring the Universe", written by the beneficiaries of the ESO-Chile Joint Committee. This annual fund provides grants for individual Chilean scientists, research infrastructures, scientific congresses, workshops for science teachers and astronomy outreach programmes for the public. In a ceremony held in Santiago on 19 June 2006, the European Organisation for Astronomical Research in the Southern Hemisphere (ESO) and the Chilean Ministry of Foreign Affairs marked the 10th Anniversary of the Supplementary Agreement, which granted to Chilean astronomers up to 10 percent of the total observing time on ESO telescopes. This agreement also established an annual fund for the development of astronomy, managed by the so-called "ESO-Chile Joint Committee". ESO PR Photo 21/06 ESO PR Photo 21/06 Ten Years ESO-Chile Agreement Ceremony The celebration event was hosted by ESO Director General, Dr. Catherine Cesarsky, and the Director of Special Policy for the Chilean Ministry of Foreign Affairs, Ambassador Luis Winter. "ESO's commitment is, and always will be, to promote astronomy and scientific knowledge in the country hosting our observatories", said ESO Director General, Dr. Catherine Cesarsky. "We hope Chile and Europe will continue with great achievements in this fascinating joint adventure, the exploration of the universe." On behalf of the Government of Chile, Ambassador Luis Winter outlined the historical importance of the Supplementary Agreement, ratified by the Chilean Congress in 1996. "Such is the magnitude of ESO-Chile Joint Committee that, only in 2005, this annual fund represented 8 percent of all financing sources for Chilean astronomy, including those from Government and universities", Ambassador Winter said. The ESO Representative and Head of Science in Chile, Dr. Felix Mirabel, and the appointed Chilean astronomer for the ESO-Chile Joint Committee, Dr. Leonardo Bronfman, also took part in the

  3. METEONETWORK: 2002-2012, 10 years of activities

    NASA Astrophysics Data System (ADS)

    Mazza, Edoardo

    2013-04-01

    The role of citizen-scientists in collecting data and observations has been increasingly crucial in the last 10 years of atmospheric sciences. Meteonetwork is a non-profit organization founded by citizen scientists in 2002, in Lombardia, with the aim of raising public awareness about meteorological and climatological issues. Throughout the years the organization, besides the continuous holding of events such as meeting, conferences and talks, has been standing out because of its forum and its wide network of weather stations. Meteonetwork's forum is, in this field, the most read and followed in the country and with its 8459 members and over 4,217,505 posts turns out to be the 17th forum over the entire country. Its network is operated in cooperation with Centro Epson Meteo and collects amateur semi-professional stations distributed all over the Italian territory, providing real-time and daily data. It consists of 706 stations, among which more than 400 regularly updated; volunteers constantly work to perform quality control and ensure data reliability. Meteonetwork has also developed several collaborations with private and public institutions, among which DRIHM - Cima Research Foundation, Centro Epson Meteo di Milano, Arpa Veneto, Arpa Emilia-Romagna, Arpa Lombardia, Arpa Friuli - Venezia Giulia, Servizio Glaciologico Lombardo, C. N. R. - C. I. S. A, Università di Pisa, Università di Milano, University of Aberdeen, Protezione Civile - Regione Lombardia, Protezione Civile - Regione Piemonte stand out. As WMO emphasized in 2001 World Meteorological Day "Volunteers for the weather, climate and water" the contribution of citizen-scientists to scientific studies is remarkable. In this perspective Meteonetwork and the University of Milan, in April 2011, started a project of technical and scientific cooperation called Weatherness. The university is provided with data gathered by Meteoneonetwork's stations with the aim of improving the knowledge of the impact that heat

  4. 10 years of Terra Outreach over the Internet

    NASA Astrophysics Data System (ADS)

    Yuen, K.; Riebeek, H.; Chambers, L. H.

    2009-12-01

    1 Author Yuen, Karen JPL (818) 393-7716 2 Author Riebeek, Holli Sigma Space Corporation (department) at NASA Goddard Space Flight Center (Institution), Greenbelt, Maryland 3 Author Chambers, Lin NASA Abstract: Since launch, Terra has returned about 195 gigabytes (level 0) of data per day or 1 terabyte every 5 days. Few outlets were able to accommodate and quickly share that amount of information as well as the Internet. To honor the 10-year anniversary of the launch of Terra, we would like to highlight the education and outreach efforts of the Terra mission on the Internet and its reach to the science attentive public. The Internet or web has been the primary way of delivering Terra content to different groups- from formal and informal education to general public outreach. Through the years, many different web-based projects have been developed, and they were of service to a growing population of the science attentive public. One of Terra’s original EPO activities was the Earth Observatory. It was initially dedicated to telling the remote sensing story of Terra, but quickly grew to include science and imagery from other sensors. The web site allowed for collaboration across NASA centers, universities and other organizations by exchanging and sharing of story ideas, news and images. The award winning Earth Observatory helped pave the way for the more recently funded development of the Climate Change website. With its specific focus on climate change studies, once again, Terra stories and images are shared with an even more specific audience base. During the last 10 years, Terra as a mission has captured the imagination of the public through its visually stunning and artistically arresting images. With its five instruments of complementary but unique capabilities, the mission gave the world not just pretty pictures, but scientific data-based images. The world was able to see from space everything from calving icebergs to volcanic eruption plumes and the eye of a

  5. Adolescents’ attitudes toward sports, exercise and fitness predict physical activity 5 and 10 years later

    PubMed Central

    Graham, Dan J.; Sirard, John R.; Neumark-Sztainer, Dianne

    2011-01-01

    Objective To determine whether adolescent attitudes towards sports, exercise and fitness predict moderate-to-vigorous physical activity (MVPA) 5 and 10 years later. Method A diverse group of 1902 adolescents participating in Project EAT (Eating and Activity in Teens), reported weekly MVPA and attitudes toward sports, exercise and fitness in EAT-I (1998-99), EAT-II (2003-04), and EAT-III (2008-09). Results Mean MVPA was 6.4, 4.8, and 4.0 hrs/wk at baseline, 5-yr, and 10-yr follow-up, respectively. Attitudes toward sports, exercise, and fitness together predicted MVPA at 5- and 10-years. Among the predictors of 5- and 10-year MVPA, attitude’s effect size, though modest, was comparable to the effect sizes for sports participation and BMI. Adolescents with more-favorable attitudes toward sports, exercise and fitness engaged in approximately 30-40% more weekly MVPA at follow-up (1.7 hr/wk at 5 years and 1.2 hr/wk at 10 years) than those with less-favorable attitudes. Conclusion Adolescents’ exercise-related attitudes predict subsequent MVPA independent of baseline behavior suggesting that youth MVPA promotion efforts may provide long-term benefits by helping youth develop favorable exercise attitudes. PMID:21130803

  6. Functional and anatomic consequences of diabetic pregnancy on memory in 10-year-old children

    PubMed Central

    Thomas, Kathleen M.; Langworthy, Sara; Georgieff, Michael K.; Nelson, Charles A.

    2015-01-01

    Objective Pregnancies complicated by diabetes mellitus impair offspring memory functions during infancy and early childhood. The purpose of this study was to investigate the long term consequences of such pregnancies on memory and memory-related brain regions in 10-year-old children. Method Nineteen (19) children of diabetic mothers (CDMs) and thirty-five (35) children of non-diabetic mothers participated in this 10 year follow-up study. Memory performance was assessed using a continuous recognition memory task during which children made old/new judgments in response to pictures of concrete and abstract objects presented after different lags or delays. In addition, the volume of the hippocampal formation was measured using high resolution structural images. Results At 10 years of age, recognition memory performance of CDMs did not differ from children of non-diabetic mothers. Similarly, the volume of the hippocampal formation did not differ between groups. However, the size of the hippocampal formation in CDMs predicted the time those children needed to provide accurate responses in the continuous recognition memory task. Conclusion CDMs do not show memory impairments by 10 years of age, despite evidence for such impairments early in life. However, subtle differences in underlying neural processes may still be present. These results have important implications for long-term cognitive development of CDMs. PMID:26348971

  7. Variations in Titan's Ionospheric Densities over a 10 Year Time Period of the Cassini Mission

    NASA Astrophysics Data System (ADS)

    Madanian, H.; Cravens, T.; Richard, M. S.; Edberg, N. J. T.; Westlake, J. H.; Wahlund, J. E.; Waite, J. H., Jr.; Perryman, R.

    2015-12-01

    Titan hosts the most chemically complex atmosphere in the solar system. The first encounter of the Cassini spacecraft with Titan was in October 2004 with a closest approach altitude of 1147km. Since then the Cassini has made measurements of the ionospheric species over multiple flybys and has provided a unique opportunity to study long term effects on Titan's ionosphere including solar activity cycle. It has been shown that solar extreme ultraviolet radiation is the main source of ion production and production rates are highly dependent on solar zenith angle. We use data from the ion and Neutral Mass Spectrometer (INMS) and the Radio and Plasma Wave Science-Langmuir probe (RPWS-LP) instruments onboard the Cassini spacecraft to investigate changes in the ion composition of the ionosphere. We compare the observations with the results of our ionospheric models. Data from 21 targeted Titan flybys are used, covering the declining phase of solar cycle 23 into the double peak of solar cycle 24. We show that the ion densities have in fact increased during the high solar activity, especially at altitudes near the ionospheric peak, and unlike Earth, the Titan's thermosphere is contracted during high solar activity. Charge neutrality is assumed near the peak of the ionosphere, however difference exists between INMS total ion densities and RPWS-LP electron densities and it becomes more noticeable at high solar activity. This may be for several reasons including enhanced negative ion densities and increased electron recombination rates. The model results agree reasonably well with the in-situ measurements for most ion species at low and high solar activity conditions although overproduction exists for some ions (e.g. HCNH+) and underproduction is seen for some heavier species such as C7H7+.

  8. In Brief: Chandra Observatory marks 10 years in space

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2009-08-01

    NASA's Chandra X-ray Observatory, originally envisioned as a 5-year mission, was deployed into an elliptical orbit around Earth 10 years ago, on 23 July 1999. The most powerful X-ray telescope yet, Chandra has provided a peak into the high-energy universe and has independently confirmed the existence of dark energy. Martin Weisskopf, Chandra project scientist at NASA's Marshall Space Flight Center, Huntsville, Ala., said discoveries made possible by the observatory “have made dramatic changes to our understanding of the universe and its constituents.” “The Great Observatories program—of which Chandra is a major part—shows how astronomers need as many tools as possible to tackle the big questions out there,” said Ed Weiler, associate administrator of NASA's Science Mission Directorate at NASA Headquarters in Washington. The Hubble Space Telescope, Compton Gamma Ray Observatory, and Spitzer Space Telescope are NASA's other Great Observatories. For more information, visit http://chandra.harvard.edu/ten/ and http://chandra.nasa.gov.

  9. Competition, resources, and vegetation during 10 years in native grassland.

    PubMed

    Wilson, Scott D

    2007-12-01

    A 10-year experiment tested for variation in competition intensity over time in a natural grassland at the northern edge of the Great Plains. Growing-season precipitation varied fivefold during the study. All ecosystem-level variables varied significantly among years, and most covaried in expected ways. The covers of all common grasses possessing the C3 photosynthetic pathway varied significantly among years; in contrast, all common species with traits associated with drought tolerance (a C4 grass, a lichen, a spikemoss, and a subshrub) did not vary. Annual transplant experiments measured the competitive effects of neighbors on the growth of individuals of the native grass Bouteloua gracilis. A significant interaction between year and competition showed that competition intensity varied among years. The size of this effect, however, was small (eta2 = 0.074) relative to the size of the direct effect of competition (eta2 = 0.20) or the year in which the experiment was conducted (eta2 = 0.51). Further, competition intensity was not significantly related to any variable describing standing crop or resources, or species richness. Species richness was highest in years with high precipitation, standing crop, and individual growth, due to the recruitment of rare species that were absent from dry years. In summary, variation in competition intensity was statistically significant but had small effects relative to the direct effects of climate. PMID:18229830

  10. Dnepr Launch Missions: 10 Years Experience of Internatio nal Cooperation

    NASA Astrophysics Data System (ADS)

    Solovey, V. A.; Andreev, V. A.; Mikhailov, V. S.; Smagin, Y. N.; Kalnov, V. V.

    2008-08-01

    International Space Company "Kosmotras" (ISC "Kosmotras") was founded in 1997 by the decisions of the Russian Aviation and Space Agency and the National Space Agency of Ukraine. It incorporated leading space industries of Russia and Ukraine. The first Launch Contract was signed in 1998 and in 1999 Dnepr launch vehicle carrying SSTL UoSAT-12 spacecraft (SC) was launched. During 10 years of its activity in the launch services market, ISC "Kosmotras" has exercised 9 successful space launches as a result of which 39 SC were placed into orbit. The flight reliability of Dnepr Launch Vehicle (LV) is estimated as 0.97. Three configurations of Space Head Module (SHM) are available for payload accommodation: a standard- size SHM for multiple small satellite missions (cluster launches); a standard-size SHM for mid-size satellites; an extended SHM for large-size satellite. ISC "Kosmotras" exercises space launches from two launch bases: Baikonur Cosmodrome (Kazakhstan) and Yasny Launch Base (Russia). This allows flexible planning of launch operations.

  11. Dissociative recombination of H3+: 10 years in retrospect

    PubMed Central

    Larsson, Mats

    2012-01-01

    The dissociative recombination of has been an intriguing problem for more than half a century. The early experiments on during the first 20 years were carried out without mass analysis in decaying plasma afterglows, and thus the measured rates pertained to an uncontrolled mixture of and impurity ions. When mass analysis was used, the rate coefficient was determined to be an uneventful value of about 10−7 cm3 s−1, a very common rate coefficient for many molecular ions. But this was not the end of the story, not even the beginning of the end; it marked only the end of the beginning. The story I will tell in this article started about 10 years ago, when the dissociative recombination of was approaching its deepest crisis. Today, owing to an extensive experimental and theoretical effort, the state of affairs has reached a historically unique level of harmony, although there still remains many things to sort out. PMID:23028159

  12. Asian dust properties from 10 years of MISR data.

    NASA Astrophysics Data System (ADS)

    Kalashnikova, Olga; Sokolik, Irina; Garay, Michael; Wu, Dong

    2010-05-01

    We use the 10-year aerosol data record from the Multi-angle Imaging SpectroRadiometer (MISR) aboard the Terra satellite to investigate climatological linkages between the dust source activities, mid-range, and long-range transport of Asian dust. The inter-annual and seasonal variability of Asian dust loadings and properties as retrieved by MISR at selected regions along the transport routes was investigated. In particular, we examine the Taklamakan and East and Central Gobi regions (dust sources), South Korea and Japan regions (mid-range transport), and the North Pacific region along the northwestern U.S. coast (long-range transport). To avoid the gridding and averaging effects in Level 3 products, we use the Level 2 MISR data. Within each selected region, the analysis was performed to examine the multi-annual mean and variability of the aerosol optical depth and particle nonsphericity as well as time-lag correlation between the regions, taking into account the effects of MISR sampling and cloud coverage. The results will be presented and interpreted in the context of atmospheric dynamics variability, including variability of meteorological regimes in dust sources and the large-scale atmospheric circulation features controlling the trans-Pacific transport of Asian dust.

  13. Proteasome inhibitors in multiple myeloma: 10 years later

    PubMed Central

    Richardson, Paul G.; Cavo, Michele; Orlowski, Robert Z.; San Miguel, Jesús F.; Palumbo, Antonio; Harousseau, Jean-Luc

    2012-01-01

    Proteasome inhibition has emerged as an important therapeutic strategy in multiple myeloma (MM). Since the publication of the first phase 1 trials of bortezomib 10 years ago, this first-in-class proteasome inhibitor (PI) has contributed substantially to the observed improvement in survival in MM patients over the past decade. Although first approved as a single agent in the relapsed setting, bortezomib is now predominantly used in combination regimens. Furthermore, the standard twice-weekly schedule may be replaced by weekly infusion, especially when bortezomib is used as part of combination regimens in frontline therapy. Indeed, bortezomib is an established component of induction therapy for patients eligible or ineligible for autologous stem cell transplantation. Bortezomib has also been incorporated into conditioning regimens before autologous stem cell transplantation, as well as into post-ASCT consolidation therapy, and in the maintenance setting. In addition, a new route of bortezomib administration, subcutaneous infusion, has recently been approved. Recently, several new agents have been introduced into the clinic, including carfilzomib, marizomib, and MLN9708, and trials investigating these “second-generation” PIs in patients with relapsed/refractory MMs have demonstrated positive results. This review provides an overview of the role of PIs in the treatment of MM, focusing on developments over the past decade. PMID:22645181

  14. Past and next 10 years of medical informatics.

    PubMed

    Ückert, Frank; Ammenwerth, Elske; Dujat, Carl; Grant, Andrew; Haux, Reinhold; Hein, Andreas; Hochlehnert, Achim; Knaup-Gregori, Petra; Kulikowski, Casimir; Mantas, John; Maojo, Victor; Marschollek, Michael; Moura, Lincoln; Plischke, Maik; Röhrig, Rainer; Stausberg, Jürgen; Takabayashi, Katsuhiko; Winter, Alfred; Wolf, Klaus-Hendrik; Hasman, Arie

    2014-07-01

    More than 10 years ago Haux et al. tried to answer the question how health care provision will look like in the year 2013. A follow-up workshop was held in Braunschweig, Germany, for 2 days in May, 2013, with 20 invited international experts in biomedical and health informatics. Among other things it had the objectives to discuss the suggested goals and measures of 2002 and how priorities on MI research in this context should be set from the viewpoint of today. The goals from 2002 are now as up-to-date as they were then. The experts stated that the three goals: "patient-centred recording and use of medical data for cooperative care"; "process-integrated decision support through current medical knowledge" and "comprehensive use of patient data for research and health care reporting" have not been reached yet and are still relevant. A new goal for ICT in health care should be the support of patient centred personalized (individual) medicine. MI as an academic discipline carries out research concerning tools that support health care professionals in their work. This research should be carried out without the pressure that it should lead to systems that are immediately and directly accepted in practice. PMID:24952607

  15. The 10-Year Cost-Effectiveness of Lifestyle Intervention or Metformin for Diabetes Prevention

    PubMed Central

    2012-01-01

    OBJECTIVE The Diabetes Prevention Program (DPP) and its Outcomes Study (DPPOS) demonstrated that either intensive lifestyle intervention or metformin could prevent type 2 diabetes in high-risk adults for at least 10 years after randomization. We report the 10-year within-trial cost-effectiveness of the interventions. RESEARCH DESIGN AND METHODS Data on resource utilization, cost, and quality of life were collected prospectively. Economic analyses were performed from health system and societal perspectives. RESULTS Over 10 years, the cumulative, undiscounted per capita direct medical costs of the interventions, as implemented during the DPP, were greater for lifestyle ($4,601) than metformin ($2,300) or placebo ($769). The cumulative direct medical costs of care outside the DPP/DPPOS were least for lifestyle ($24,563 lifestyle vs. $25,616 metformin vs. $27,468 placebo). The cumulative, combined total direct medical costs were greatest for lifestyle and least for metformin ($29,164 lifestyle vs. $27,915 metformin vs. $28,236 placebo). The cumulative quality-adjusted life-years (QALYs) accrued over 10 years were greater for lifestyle (6.81) than metformin (6.69) or placebo (6.67). When costs and outcomes were discounted at 3%, lifestyle cost $10,037 per QALY, and metformin had slightly lower costs and nearly the same QALYs as placebo. CONCLUSIONS Over 10 years, from a payer perspective, lifestyle was cost-effective and metformin was marginally cost-saving compared with placebo. Investment in lifestyle and metformin interventions for diabetes prevention in high-risk adults provides good value for the money spent. PMID:22442395

  16. Examining the 10-Year Rebuilding Dilemma for U.S. Fish Stocks

    PubMed Central

    Patrick, Wesley S.; Cope, Jason

    2014-01-01

    Worldwide, fishery managers strive to maintain fish stocks at or above levels that produce maximum sustainable yields, and to rebuild overexploited stocks that can no longer support such yields. In the United States, rebuilding overexploited stocks is a contentious issue, where most stocks are mandated to rebuild in as short a time as possible, and in a time period not to exceed 10 years. Opponents of such mandates and related guidance argue that rebuilding requirements are arbitrary, and create discontinuities in the time and fishing effort allowed for stocks to rebuild due to differences in productivity. Proponents, however, highlight how these mandates and guidance were needed to curtail the continued overexploitation of these stocks by setting firm deadlines on rebuilding. Here we evaluate the statements made by opponents and proponents of the 10-year rebuilding mandate and related guidance to determine whether such points are technically accurate using a simple population dynamics model and a database of U.S. fish stocks to parameterize the model. We also offer solutions to many of the issues surrounding this mandate and its implementation by recommending some fishing mortality based frameworks, which meet the intent of the 10-year rebuilding requirement while also providing more flexibility. PMID:25375788

  17. Factors influencing infection in 10 years of battlefield open tibia fractures.

    PubMed

    Penn-Barwell, J G; Bennett, P M; Mortiboy, D E; Fries, C A; Groom, A F G; Sargeant, I D

    2016-04-01

    The aim of this study was to characterise severe open tibial shaft fractures sustained by the UK military personnel over 10 years of combat in Iraq and Afghanistan. The UK military Joint Theatre Trauma Registry was searched for all such injuries, and clinical records were reviewed for all patients. One hundred Gustilo-Anderson III tibia fractures in 89 patients were identified in the 10 year study period; the majority sustained injuries through explosive weapons (63, 68 %) with the remainder being injured from gunshot wounds. Three fractures were not followed up for 12 months and were therefore excluded. Twenty-two (23 %) of the remaining 97 tibial fractures were complicated by infection, with S. aureus being the causative agent in 13/22 infected fractures (59 %). Neither injury severity, mechanism, the use of an external fixator, the need for vascularised tissue transfer nor smoking status was associated with subsequent infection. Bone loss was significantly associated with subsequent infection (p < 0.0001, Fisher's exact test). This study presents 10 years of open tibial fractures sustained in Iraq and Afghanistan. Most infection in combat open tibia fractures is caused by familiar organisms, i.e. S. aureus. While the overall severity of a casualty's injuries was not associated with infection, the degree of bone loss from the fracture was. PMID:26993111

  18. 24 CFR 203.269 - Method of payment of periodic MIP.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Method of payment of periodic MIP...-Periodic Payment § 203.269 Method of payment of periodic MIP. In cases that the Commissioner deems..., that periodic MIP be remitted electronically. Open-end Insurance Charges—All Mortgages...

  19. 24 CFR 203.269 - Method of payment of periodic MIP.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Method of payment of periodic MIP...-Periodic Payment § 203.269 Method of payment of periodic MIP. In cases that the Commissioner deems..., that periodic MIP be remitted electronically. Open-end Insurance Charges—All Mortgages...

  20. 24 CFR 203.269 - Method of payment of periodic MIP.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Method of payment of periodic MIP...-Periodic Payment § 203.269 Method of payment of periodic MIP. In cases that the Commissioner deems..., that periodic MIP be remitted electronically. Open-end Insurance Charges—All Mortgages...

  1. 24 CFR 203.269 - Method of payment of periodic MIP.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Method of payment of periodic MIP...-Periodic Payment § 203.269 Method of payment of periodic MIP. In cases that the Commissioner deems..., that periodic MIP be remitted electronically. Open-end Insurance Charges—All Mortgages...

  2. 24 CFR 203.269 - Method of payment of periodic MIP.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Method of payment of periodic MIP...-Periodic Payment § 203.269 Method of payment of periodic MIP. In cases that the Commissioner deems..., that periodic MIP be remitted electronically. Open-end Insurance Charges—All Mortgages...

  3. A novel gene detection method based on period-3 property.

    PubMed

    Huang, Lun; Bataineh, Mohammad Al; Atkin, G E; Wang, Siyun; Zhang, Wei

    2009-01-01

    Processing of biomolecular sequences using communication theory techniques provides powerful approaches for solving highly relevant problems in bioinformatics by properly mapping character strings into numerical sequences. We provide an optimized procedure for predicting protein-coding regions in DNA sequences based on the period-3 property of coding region. We present a digital correlating and filtering approach in the process of predicting these regions, and find out their locations by using the magnitude of the output sequence. These approaches result in improved computational techniques for the solution of useful problems in genomic information science and technology. PMID:19963599

  4. Adolescent drug trafficking trends in the United Kingdom--a 10-year retrospective analysis.

    PubMed

    Vale, Ellen Louise Eva; Kennedy, Patrick John

    2004-12-01

    This paper reports data from HM Customs and Excise (HMCE) of recorded cases of adolescent drug trafficking through all sea and air points of entry into the UK over a 10-year period (May 1992-May 2002). We report the characteristics of 38 cases of mixed gender and nationality ranging in age between 13 and 18 years who have been apprehended by HMCE due to the illegal importation of drugs. Highlighted is an increasing trend in UK national male and female adolescents being apprehended for drug trafficking. Of particular note is the observation that more young adolescent females were apprehended importing large consignments of Class A substances than their male counterparts.

  5. 10-year experience of injuries sustained during clearance of anti-personnel mines.

    PubMed

    Brown, R; Chaloner, E; Mannion, S; Cheatle, T

    2001-12-15

    Clearance of anti-personnel mines and unexploded ordnance in countries recovering from war usually continues long after conflict has ceased. We prospectively recorded 92 traumatic injuries sustained by 73 mineclearers working in seven countries over a period of 10 years. 15% of injuries were fatal, with an incidence of 116 injuries per 100000 workers per year. Limb injury occurred in 59% of cases, with an overall amputation rate of 30%. 44% of injuries were sustained by workers handling a mine, resulting in severe upper limb and facial injuries. The incidence of facial injuries fell after the introduction of visors.

  6. Parathyroidectomy in the treatment of patients with chronic renal failure: a 10-year review.

    PubMed

    Bessell, J R; Proudman, W D; Parkyn, R F; Disney, A P

    1993-01-01

    The technique and outcome of surgery for the manifestations of secondary hyperparathyroidism are described. Forty-seven patients were analysed retrospectively over a 10-year period. Total parathyroidectomy and autotransplantation to the forearm was performed in all but five patients. Improvement occurred in 87 per cent of patients and there were no graft failures. Of six deaths, none was related to surgery. Four patients had recurrent hyperparathyroidism, three being graft dependent and one requiring re-exploration of the neck. Total parathyroidectomy and autotransplantation is a safe and effective approach. The major management problem was graft hyperplasia, seen in three of the 47 patients and managed by simple excision.

  7. A 10-Year Climatology of Amazonian Rainfall Derived from Passive Microwave Satellite Observations

    NASA Technical Reports Server (NTRS)

    Negri, Andrew J.; Anagnostou, Emmanouil N.; Adler, Robert F.

    1998-01-01

    In this study we present and describe a satellite-derived precipitation climatology over northern South America using a passive microwave technique, the Goddard Profiling Algorithm. A period of data slightly longer than 10 years is examined. The climatologies take the form of the mean estimated (adjusted) rainfall for a 10-year (+) period, with sub-divisions by month and meteorological season. For the six-year period 1992-1997, when two satellites were in operation, diurnal variability (to the extent it is discerned by four unequally spaced observations) is presented. We find an alternating pattern of morning and maxima stretching from the northeast (Atlantic coast) clear across the continent to the Pacific. The effects of topography, coastlines and geography (river valleys) on the rainfall patterns are clear. Interannual variability is examined by computing the deviations of yearly and warm season (DJF) rainfall from their respective long-term means. Interannual variability of the diurnal nature of the rainfall is presented, and the strong El Nino event of 1997-1998 is discussed.

  8. Spectrum of Sinonasal Tumors: A 10-year Experience at a Tertiary Care Hospital in North India

    PubMed Central

    Shirazi, Nadia; Bist, Sampan S.; Selvi, Thamarai N.; Harsh, Meena

    2015-01-01

    Objective Sinonasal tumors are a highly heterogeneous group of tumors that account for less than 1% of all cancers. Precise diagnosis is essential because the natural history, treatment, and prognosis vary for different neoplasms. We reviewed 610 cases of sinonasal lesions to understand this entity better. Methods A total of 610 sinonasal biopsies/specimens were received over a period of 10 years (2004–14). All the samples were processed and stained with hematoxylin and eosin. Special staining for microorganisms and immunohistochemistry were performed where indicated. Results Benign lesions were 72% with nasal polyp being the most common. Malignant lesions made up 21.2% of lesions with nasopharyngeal carcinoma being the most common while 7.7% cases were inflammatory/non-neoplastic. The most common cause for this was fungal sinusitis. The maxillary sinus was the most frequently involved site in all the lesions (62%). The average age of presentation was 40 years old, and the male to female ratio was 3:1 in those with benign tumors. The average age of presentation in the malignant and inflammatory group were 45 and 43 years, respectively, with an almost equal sex ratio in both categories. Computed tomography and magnetic resonance imaging scans were done in virtually all cases to assess the extent of the tumor as well as bony destruction. Local recurrence was the most frequent cause of treatment failure. Conclusion Tumors of the nasal cavity are often grouped with those in the paranasal sinuses. Benign tumors constituted approximately 75% of tumors in our hospital. Squamous cell carcinoma was the most common malignancy of this region. These tumors need to be studied closely and accurately because their proximity to vital structures pose significant challenges for their treatment and may be the source of significant patient morbidity. PMID:26674709

  9. HEMIPELVECTOMY: ERASTO GAERTNER HOSPITAL'S EXPERIENCES WITH 32 CASES IN 10 YEARS

    PubMed Central

    Freitas, Rosyane Rena de; Crivellaro, André Luiz Soares; Mello, Glauco José Pauka; Neto, Múrio Armani; Filho, Geraldo de Freitas; Silva, Letícia Viani da

    2015-01-01

    Objective: To show the experience of the Erasto Gaertner Hospital with hemipelvectomy surgery over a 10-year period. Methods: This was a retrospective study on 32 patients who underwent hemipelvectomy at Erasto Gaertner Hospital between 1998 and 2008, assessing clinical and surgical characteristics. Results: Among the 32 patients, 15 were female and 17 were male. The mean age was 37.94 years. Eight cases showed involvement of the neurovascular bundle: three were located in the iliac and extended to the thigh, two were in the acetabulum and extended to the thigh and three were in the acetabulum and pubis. Twenty-three cases presented a neurovascular bundle free from neoplasia: 11 were restricted to the iliac, six were in the acetabular region, two were in the pubic ramus and four extended to the whole hemipelvis bone. One case involved the iliac-femoral vessels: one in the pubic ramus. Seven cases of chondrosarcoma and four cases of Ewing's sarcoma represented the majority. Eight cases underwent external hemipelvectomy and 24 underwent internal hemipelvectomy (11 were type I; four were type II; two were type II + III; three were type III and four were type IV). Of these 24 cases, 13 did not have any reconstruction, 10 had a fibular graft and one had an iliacfemoral vein and artery prosthesis. Twenty-six surgeries were curative and six were palliative. There were 14 deaths. Survival of two and five years was seen in 11 and 10 cases, respectively. For six cases, less than two years had passed since the operation. Three cases were lost during follow-up. Conclusion: This study shows the experiences of an oncology reference service specializing in highly complex surgical treatment. PMID:27022573

  10. 10 years of Cassini/VIMS observations at Titan

    NASA Astrophysics Data System (ADS)

    Sotin, C.; Brown, R. H.; Baines, K. H.; Barnes, J.; Buratti, B. J.; Clark, R. N.; Jaumann, R.; LeMouelic, S.; Nicholson, P. D.; Rodriguez, S.; Soderblom, J.; Soderblom, L.; Stephan, K.

    2014-04-01

    The interplanetary space probe Cassini/Huygens reached Saturn in July 2004 after seven years of cruise phase. Today, the German-lead Cosmic Dust Analyser (CDA) is operated continuously for 10 years in orbit around Saturn. During the cruise phase CDA measured the interstellar dust flux at one AU distance from the Sun, the charge and composition of interplanetary dust grains and the composition of the Jovian nanodust streams. The first discovery of CDA related to Saturn was the measurement of nanometer sized dust particles ejected by its magnetosphere to interplanetary space with speeds higher than 100 km/s. Their origin and composition was analysed and an their dynamical studies showed a strong link to the conditions of the solar wind plasma flow. A recent surprising result was, that stream particles stem from the interior of Enceladus. Since 2004 CDA measured millions of dust impacts characterizing the dust environment of Saturn. The instrument showed strong evidence for ice geysers located at the south pole of Saturn's moon Enceladus in 2005. Later, a detailed compositional analysis of the salt-rich water ice grains in Saturn's E ring system lead to the discovery of liquid water below the icy crust connected to an ocean at depth feeding the icy jets. CDA was even capable to derive a spatially resolved compositional profile of the plume during close Enceladus flybys. A determination of the dust-magnetosphere interaction and the discovery of the extended E ring allowed the definition of a dynamical dust model of Saturn's E ring describing the observed properties. The measured dust density profiles in the dense E ring revealed geometric asymmetries. Cassini performed shadow crossings in the ring plane and dust grain charges were measured in shadow regions delivering important data for dust-plasma interaction studies. In the last years, dedicated measurement campaigns were executed by CDA to monitor the flux of interplanetary and interstellar dust particles reaching

  11. Background Oriented Schlieren Method Using Multi-scale Periodic Pattern

    NASA Astrophysics Data System (ADS)

    Hatanaka, Kazuaki; Saito, Tsutomu

    Background oriented schlieren (BOS) method is an optical visualization technique for flow fields utilizing the phenomenon that the refractive index of fluid changes when a disturbance occurs in the flow field [1, 2].

  12. Construction of Large Period Symplectic Maps by Interpolative Methods

    SciTech Connect

    Warnock, Robert; Cai, Yunhai; Ellison, James A.; /New Mexico U.

    2009-12-17

    The goal is to construct a symplectic evolution map for a large section of an accelerator, say a full turn of a large ring or a long wiggler. We start with an accurate tracking algorithm for single particles, which is allowed to be slightly non-symplectic. By tracking many particles for a distance S one acquires sufficient data to construct the mixed-variable generator of a symplectic map for evolution over S, given in terms of interpolatory functions. Two ways to find the generator are considered: (1) Find its gradient from tracking data, then the generator itself as a line integral. (2) Compute the action integral on many orbits. A test of method (1) has been made in a difficult example: a full turn map for an electron ring with strong nonlinearity near the dynamic aperture. The method succeeds at fairly large amplitudes, but there are technical difficulties near the dynamic aperture due to oddly shaped interpolation domains. For a generally applicable algorithm we propose method (2), realized with meshless interpolation methods.

  13. Stunted at 10 Years. Linear Growth Trajectories and Stunting from Birth to Pre-Adolescence in a Rural Bangladeshi Cohort

    PubMed Central

    Svefors, Pernilla; Rahman, Anisur; Ekström, Eva-Charlotte; Khan, Ashraful Islam; Lindström, Emma; Persson, Lars Åke; Ekholm Selling, Katarina

    2016-01-01

    Background Few studies in low-income settings analyse linear growth trajectories from foetal life to pre-adolescence. The aim of this study is to describe linear growth and stunting from birth to 10 years in rural Bangladesh and to analyse whether maternal and environmental determinants at conception are associated with linear growth throughout childhood and stunting at 10 years. Methods and Findings Pregnant women participating in the MINIMat trial were identified in early pregnancy and a birth cohort (n = 1054) was followed with 19 growth measurements from birth to 10 years. Analyses of baseline predictors and mean height-for-age Z-scores (HAZ) over time were modelled using GLMM. Logistic regression analysis was used to investigate the associations between baseline predictors and stunting (HAZ<-2) at 10 years. HAZ decreased to 2 years, followed by an increase up to 10 years, while the average height-for-age difference in cm (HAD) to the WHO reference median continued to increase up to 10 years. Prevalence of stunting was highest at 2 years (50%) decreasing to 29% at 10 years. Maternal height, maternal educational level and season of conception were all independent predictors of HAZ from birth to pre-adolescence (p<0.001) and stunting at 10 years. The highest probability to be stunted at 10 years was for children born by short mothers (<147.5 cm) (ORadj 2.93, 95% CI: 2.06–4.20), mothers with no education (ORadj 1.74, 95% CI 1.17–2.81) or those conceived in the pre-monsoon season (ORadj 1.94, 95% CI 1.37–2.77). Conclusions Height growth trajectories and prevalence of stunting in pre-adolescence showed strong intergenerational associations, social differentials, and environmental influence from foetal life. Targeting women before and during pregnancy is needed for the prevention of impaired child growth. PMID:26934484

  14. Enteroviruses in Spain: virological and epidemiological studies over 10 years (1988-97).

    PubMed Central

    Trallero, G.; Casas, I.; Tenorio, A.; Echevarria, J. E.; Castellanos, A.; Lozano, A.; Breña, P. P.

    2000-01-01

    A total of 15,662 clinical samples were analysed for enterovirus (EV) isolation in cell cultures during a 10-year period (1988-97). Furthermore, 210 isolates of EV obtained in primary laboratories within Spain from patients with meningitis were characterized. The total number of EV typed was 758, including 727 non-polio EV and 31 Sabin-like (SL) polioviruses. Twenty-eight EV serotypes were represented. Echoviruses comprised 90% (653/727) of fully typed non-polio EV. The four most prevalent serotypes were echovirus 30, echovirus 9, echovirus 6 and echovirus 4. Echovirus 30 was the main serotype associated with meningitis. Echovirus 9 was the aetiological agent in 20 outbreaks of meningitis while the occurrence of echovirus 6 was localized in 1 year (1997). Coxsackieviruses A and B occurred in 3 and 7% of the non-polio EV respectively. Coxsackievirus B5 presented the relative greater abundance. This paper examines the epidemiology of EV in Spain to serotype level over a 10-year period with special attention to non-polio EV associated with meningitis. PMID:10982074

  15. Factors associated with arterial stiffness in children aged 9-10 years

    PubMed Central

    Batista, Milena Santos; Mill, José Geraldo; Pereira, Taisa Sabrina Silva; Fernandes, Carolina Dadalto Rocha; Molina, Maria del Carmen Bisi

    2015-01-01

    OBJECTIVE To analyze the factors associated with stiffness of the great arteries in prepubertal children. METHODS This study with convenience sample of 231 schoolchildren aged 9-10 years enrolled in public and private schools in Vitória, ES, Southeastern Brazil, in 2010-2011. Anthropometric and hemodynamic data, blood pressure, and pulse wave velocity in the carotid-femoral segment were obtained. Data on current and previous health conditions were obtained by questionnaire and notes on the child’s health card. Multiple linear regression was applied to identify the partial and total contribution of the factors in determining the pulse wave velocity values. RESULTS Among the students, 50.2% were female and 55.4% were 10 years old. Among those classified in the last tertile of pulse wave velocity, 60.0% were overweight, with higher mean blood pressure, waist circumference, and waist-to-height ratio. Birth weight was not associated with pulse wave velocity. After multiple linear regression analysis, body mass index (BMI) and diastolic blood pressure remained in the model. CONCLUSIONS BMI was the most important factor in determining arterial stiffness in children aged 9-10 years. PMID:25902563

  16. Impact of Adolescent Alcohol and Drug Use on Neuropsychological Functioning in Young Adulthood: 10-Year Outcomes

    PubMed Central

    Hanson, Karen L.; Medina, Krista Lisdahl; Padula, Claudia B.; Tapert, Susan F.; Brown, Sandra A.

    2011-01-01

    Background Alcohol and other substance use disorders (AUD/SUD) are common among youth and often continue into adulthood; therefore, the neurocognitive effects of substance use are of great concern. Because neuromaturation continues into young adulthood, youth with AUD/SUD may be at risk for lasting cognitive decrements. This study prospectively examines neuropsychological functioning over 10 years as a function of AUD/SUD history and outcomes. Methods The 51 participants consisted of 18 youth with persisting AUD/SUD, 19 youth with remitted AUD/SUD, and 14 community youth with no AUD/SUD history followed over 10 years (ages 16 to 27 on average) with neuropsychological testing and substance use interviews on 8 occasions. Neuropsychological performance from baseline to 10-year follow-up was compared between the three groups. Results Despite scoring higher than controls at intake, both AUD/SUD groups showed a relative decline in visuospatial construction at 10-year follow-up (p=.001). Regressions showed that alcohol use (β=−.33, p < .01) and drug withdrawal symptoms (β=−.31, p<.05) over follow-up were predictive of year 10 visuospatial function. Alcohol use also predicted verbal learning and memory (β=−.28, p<.05), while stimulant use predicted visual learning and memory function (β=−.33, p=.01). More recent substance use was associated with poorer executive function (β=.28, p<.05). Discussion These findings confirm prior studies suggesting that heavy, chronic alcohol and other substance use persisting from adolescence to young adulthood may produce cognitive disadvantages, primarily in visuospatial and memory abilities. Youth who chronically consume heavy quantities of alcohol and/or experience drug withdrawal symptoms may be particularly at risk for cognitive deterioration by young adulthood. PMID:21532924

  17. Changes in Pulmonary Function Up to 10 Years After Locoregional Breast Irradiation

    SciTech Connect

    Erven, Katrien; Weltens, Caroline; Nackaerts, Kristiaan; Fieuws, Steffen; Decramer, Marc; Lievens, Yolande

    2012-02-01

    Purpose: To evaluate the long-term impact of locoregional breast radiotherapy (RT) on pulmonary function tests (PFTs). Methods and Materials: This study included 75 women who underwent postoperative locoregional breast RT. PFTs were performed before RT and 3, 6, and 12 months and 8 to 10 years after RT. By use of univariate and multivariate analyses, the impact of treatment- and patient-related factors on late changes in PFTs was evaluated. Results: During the first year after RT, all PFTs significantly worsened at 3 to 6 months after RT (p < 0.05). At 12 months, forced vital capacity (FVC), vital capacity (VC), and forced expiratory volume in 1 second (FEV{sub 1}) recovered almost to baseline values, whereas total lung capacity (TLC) and diffusion capacity of carbon monoxide (DL{sub CO}) recovered only slightly and were still found to be decreased compared with baseline (p < 0.05). At 8 to 10 years after RT, mean reductions in FEV{sub 1} of 4% (p = 0.03) and in VC, DL{sub CO}, and TLC of 5%, 9%, and 11% (all p < 0.0001), respectively, were observed compared with pre-RT values. On multivariate analysis, tamoxifen use negatively affected TLC at 8 to 10 years after RT (p = 0.033), whereas right-sided irradiation was associated with a late reduction in FEV{sub 1} (p = 0.027). For FEV{sub 1} and DL{sub CO}, an early decrease was predictive for a late decrease (p = 0.003 and p = 0.0009, respectively). Conclusions: The time course of PFT changes after locoregional RT for breast cancer follows a biphasic pattern. An early reduction in PFTs at 3 to 6 months with a partial recovery at 12 months after RT is followed by a late, more important PFT reduction up to 8 to 10 years after RT. Tamoxifen use may have an impact on this late decline in PFTs.

  18. The Dynamics of Free Recall and Their Relation to Rehearsal between 8 and 10 Years of Age

    ERIC Educational Resources Information Center

    Lehmann, Martin; Hasselhorn, Marcus

    2010-01-01

    The present study longitudinally examined changes in recall in children between the ages of 8 and 10 years. Given the increasingly sophisticated use of memory strategies during this developmental period, correspondences between study and recall dynamics were of particular interest. Seventy-six children performed free-recall tasks on 5 occasions…

  19. 26 CFR 601.204 - Changes in accounting periods and in methods of accounting.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 20 2010-04-01 2010-04-01 false Changes in accounting periods and in methods of... (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601.204 Changes in accounting periods and in methods of accounting. (a) Accounting periods. A taxpayer...

  20. 26 CFR 601.204 - Changes in accounting periods and in methods of accounting.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 20 2013-04-01 2013-04-01 false Changes in accounting periods and in methods of... (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601.204 Changes in accounting periods and in methods of accounting. (a) Accounting periods. A taxpayer...

  1. Tracking 10-year competitive winning performance of judo athletes across age groups.

    PubMed

    Julio, Ursula F; Takito, Monica Y; Mazzei, Leandro; Miarka, Bianca; Sterkowicz, Stanislaw; Franchini, Emerson

    2011-08-01

    Little information is available concerning early specialization and competitive success in judo across the early training years. Thus, the present objective was to verify the stability of individual competitive performance of a state-level championship for judo athletes who had been previously successful. For this, 406 athletes from six age groups (9 to 20+ years old) of each sex were followed for 10 years. Using recorded data from the São Paulo State Judo Federation beginning in 1999, the scores and standings for these judo players were analyzed. The proportion of medal winners during this period was not constant, differing from the grand mean in all groups of both 204 males and 202 females. At the end of this period, only 7% of the male and 5% of the female athletes had maintained their competitive levels. Successful competitive performance in early judo competition was not associated with success later in adulthood. PMID:21987915

  2. Tracking 10-year competitive winning performance of judo athletes across age groups.

    PubMed

    Julio, Ursula F; Takito, Monica Y; Mazzei, Leandro; Miarka, Bianca; Sterkowicz, Stanislaw; Franchini, Emerson

    2011-08-01

    Little information is available concerning early specialization and competitive success in judo across the early training years. Thus, the present objective was to verify the stability of individual competitive performance of a state-level championship for judo athletes who had been previously successful. For this, 406 athletes from six age groups (9 to 20+ years old) of each sex were followed for 10 years. Using recorded data from the São Paulo State Judo Federation beginning in 1999, the scores and standings for these judo players were analyzed. The proportion of medal winners during this period was not constant, differing from the grand mean in all groups of both 204 males and 202 females. At the end of this period, only 7% of the male and 5% of the female athletes had maintained their competitive levels. Successful competitive performance in early judo competition was not associated with success later in adulthood.

  3. The abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, India

    PubMed Central

    Srivastava, Amresh Kumar; Stitt, Larry; Thakar, Meghana; Shah, Nilesh; Chinnasamy, Gurusamy

    2009-01-01

    Background The outcome of first episode schizophrenia has several determinants. Socioecological factors, particularly living conditions, migration, community and culture, not only affect the level of risk but also the outcome. Mega cities around the world show a unique socioecological condition that has several challenges for mental health. The present study reports on the long-term status of patients with schizophrenia in such a mega city: Mumbai, India. Aim This study aims to reveal the long-term outcome of patients suffering from schizophrenia with special reference to clinical symptoms and social functioning. Methods The cohort for this study was drawn from a 10-year follow-up of first episode schizophrenia. Patients having completed 10 years of consistent treatment after first hospitalisation were assessed on psychopathological and recovery criteria. Clinical as well as social parameters of recovery were evaluated. Descriptive statistics with 95% confidence intervals are provided. Results Of 200 patients recruited at the beginning of this study, 122 patients (61%) were present in the city of Mumbai at the end of 10-year follow-up study period. Among 122 available patients, 101 patients (50.5%) were included in the assessment at the end of 10-year follow-up study period, 6 patients (3.0%) were excluded from the study due to changed diagnosis, and 15 patients (7.5%) were excluded due to admission into long-term care facilities. This indicates that 107 out of 122 available patients (87.7%) were living in the community with their families. Out of 101 (50.5%) patients assessed at the end of 10 years, 61 patients (30.5%) showed improved recovery on the Clinical Global Impression Scale, 40 patients (20%) revealed no improvement in the recovery, 43 patients (72.9%) were able to live independently, and 24 patients (40%) were able to find employment. Conclusion With 10 years of treatment, the recovery rate among schizophrenia patients in Mumbai was 30.5%. Among the

  4. Clinical performance of three anterior restorative materials over 10 years.

    PubMed

    Jokstad, A; Mjör, I A; Nilner, K; Kaping, S

    1994-02-01

    The long-term performance of two chemically activated composite resins was compared to that of one silicate cement. Bulk and cavosurface marginal discoloration was evaluated with both an indirect photographic method and the direct US Public Health Service evaluation system. The results confirmed that composite resins had superior performance but higher secondary caries incidence than did silicate cements. The macrofilled composite resins showed better clinical performance than the microfilled restorations, as well as similar incidences of bulk and marginal discoloration. The agreement between the scores obtained with the direct evaluation criteria and those resulting from the indirect evaluation method was relatively poor. The indirect scores were usually the same or poorer than the direct clinical scores. The results indicated that the clinical evaluation may be the least sensitive of the two methods. The discrepancy in the scorings may, on the other hand, signify that the indirect photographic method records reflectance spectra that are not normally obtained in vivo.

  5. Infrared photometry of Venus - Variation during 10 years?

    NASA Astrophysics Data System (ADS)

    Nagata, T.; Sato, S.; Mukai, T.; Mukai, S.

    1985-08-01

    Narrowband filter (3.6-micron wavelength, 0.08-micron bandwidth) observations of the infrared flux of Venus are reported. The observations over the period from 1982 through 1984 covered a range of phase angle from 27 to 94 degrees. Normalized values of flux at the Venus-earth distance of 1 AU were (4.0-5.4) x 10 to the -17th watt per square centimeter per inverse centimeter, and the phase angle dependence of the data is rather weak. Furthermore, when the evening terminator of Venus was seen, lower values of flux were obtained, in contrast with higher values at the morning terminator. The phase angle dependence is quite different from that of Martonchik and Beer (1975), the difference possibly suggesting an intrinsic time variation of haze particles over ten years in the upper haze layer of the Venus cloudcover.

  6. Development of 5- and 10-year-old pediatric phantoms based on polygon mesh surfaces

    SciTech Connect

    Melo Lima, V. J. de; Cassola, V. F.; Kramer, R.; Oliveira Lira, C. A. B. de; Khoury, H. J.; Vieira, J. W.

    2011-08-15

    Purpose: The purpose of this study is the development of reference pediatric phantoms for 5- and 10-year-old children to be used for the calculation of organ and tissue equivalent doses in radiation protection. Methods: The study proposes a method for developing anatomically highly sophisticated pediatric phantoms without using medical images. The 5- and 10-year-old male and female phantoms presented here were developed using 3D modeling software applied to anatomical information taken from atlases and textbooks. The method uses polygon mesh surfaces to model body contours, the shape of organs as well as their positions, and orientations in the human body. Organ and tissue masses comply with the corresponding data given by the International Commission on Radiological Protection (ICRP) for the 5- and 10-year-old reference children. Bones were segmented into cortical bone, spongiosa, medullary marrow, and cartilage to allow for the use of micro computer tomographic ({mu}CT) images of trabecular bone for skeletal dosimetry. Results: The four phantoms, a male and a female for each age, and their organs are presented in 3D images and their organ and tissue masses in tables which show the compliance of the ICRP reference values. Dosimetric data, calculated for the reference pediatric phantoms by Monte Carlo methods were compared with corresponding data from adult mesh phantoms and pediatric stylized phantoms. The comparisons show reasonable agreement if the anatomical differences between the phantoms are properly taken into account. Conclusions: Pediatric phantoms were developed without using medical images of patients or volunteers for the first time. The models are reference phantoms, suitable for regulatory dosimetry, however, the 3D modeling method can also be applied to medical images to develop patient-specific phantoms.

  7. Treatment of the edentulous atrophic maxilla using zygomatic implants: evaluation of survival rates over 5-10 years.

    PubMed

    Yates, J M; Brook, I M; Patel, R R; Wragg, P F; Atkins, S A; El-Awa, A; Bakri, I; Bolt, R

    2014-02-01

    The aim of this retrospective observational cohort study was to analyse and report the 5-10-year survival rates of endosseous zygomatic implants used in the rehabilitation of the atrophic maxilla. Forty-three consecutive zygomatic implant placements in 25 patients were evaluated over a 5-10-year period. All zygomatic implant surgery was carried out under general anaesthesia. Nobel Biocare zygomatic machined-surface implants were used, and placement was undertaken using the modified sinus slot method. The main outcome measures and determinants for success were survival of the restored implants and the proportion of originally planned prostheses delivered to patients. Of the 25 patients treated, 12 were male and 13 were female; 19 were non-smokers, and the mean age at time of surgery was 64 years. Patients were treatment-planned for implant-retained bridgework, a removable prosthesis retained by fixed cast gold or milled titanium beams, or magnet-retained removable prostheses. A combination of zygomatic and conventional implants was used in all but one patient. In this study it was shown that the overall success rate for zygomatic implants was 86%, with six of the implants either failing to integrate or requiring removal due to persistent infection associated with the maxillary sinus. All patients received their planned prosthesis, although in six cases the method of retention required modification. This study illustrates that zygomatic implants are a successful and important treatment option when trying to restore the atrophic maxilla, with the potential to avoid additional augmentation/grafting procedures and resulting in a high long-term success rate. PMID:24120903

  8. Soil physicochemical properties after 10 years of animal waste applications

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Application of animal waste to cropland provides a method of waste disposal and benefits both soil and crops. The objective of this study was to evaluate the long-term effects of land application of animal waste and inorganic fertilizer on selected soil chemical and physical properties. The animal w...

  9. Experiences from 10 years of school programmes at GEOMAR Kiel

    NASA Astrophysics Data System (ADS)

    Dengg, Joachim

    2014-05-01

    GEOMAR Helmholtz Centre for Ocean Research Kiel, Germany, started a programme of cooperations with secondary schools in 2003, which has been expanding continually since that time. By active involvement of teachers and students, the Centre's research topics are communicated to schools, and young people are encouraged to develop their interest for biogeosciences. The portfolio of activities includes: project work with schools over periods from one day to several months, individual student theses at the research centre, internships, a weekly "Research Club" allowing individual experiments, summer school programmes, teacher training courses, joint activities with international partners and a video-project in which students portray scientific aspects of oceanic oxygen minimum zones (in the context of the Collaborative Research Center SFB 754) to other students. Essential prerequisites for these activities are the direct involvement of the Centre's researchers who contribute their expertise and act as role-models for the students, dedicated staff for coordination and continuity, and financial and structural support both at the research centre and the schools.

  10. Evidence-based causation in toxicology: A 10-year retrospective.

    PubMed

    James, R C; Britt, J K; Halmes, N C; Guzelian, P S

    2015-12-01

    We introduced Evidence-based Toxicology (EBT) in 2005 to address the disparities that exist between the various Weight-of-Evidence (WOE) methods typically applied in the regulatory hazard decision-making arena and urged toxicologists to adopt the evidence-based guidelines long-utilized in medicine (i.e., Evidence-Based Medicine or EBM). This review of the activities leading to the adoption of evidence-based methods and EBT during the last decade demonstrates how fundamental concepts that form EBT, such as the use of systematic reviews to capture and consider all available information, are improving toxicological evaluations performed by various groups and agencies. We reiterate how the EBT framework, a process that provides a method for performing human chemical causation analyses in an objective, transparent and reproducible manner, differs significantly from past and current regulatory WOE approaches. We also discuss why the uncertainties associated with regulatory WOE schemes lead to a definition of the term "risk" that contains unquantifiable uncertainties not present in this term as it is used in epidemiology and medicine. We believe this distinctly different meaning of "risk" should be clearly conveyed to those not familiar with this difference (e.g., the lay public), when theoretical/nomologic risks associated with chemical-induced toxicities are presented outside of regulatory and related scientific parlance.

  11. Fournier's Gangrene: A Summary of 10 Years of Clinical Experience

    PubMed Central

    Oguz, Abdullah; Gümüş, Metehan; Turkoglu, Ahmet; Bozdağ, Zübeyir; Ülger, Burak Veli; Agaçayak, Elif; Böyük, Abdullah

    2015-01-01

    We aimed to present our clinical experience with FG treatment. Fournier's gangrene (FG) is a rare but serious disease characterized by progressive necrosis in the genitourinary and perineal region. The retrospective study included 43 patients. Patients were divided into 2 groups as survivors and nonsurvivors. Included in the analysis were data pertaining to demographics, predisposing factors, comorbidities, results of bacteriologic analyses, number of debridements, duration of treatment, FG Severity Index (FGSI) score, fecal diversion methods (trephine ostomy or Flexi-Seal Fecal Management System-FMS), and dressing methods (wet or negative aspiration system). In the nonsurvivor group, urea, WBC, and age were significantly higher, whereas albumin, hematocrit, platelet count, and length of hospital stay (LOHS) were significantly lower compared to the survivor group. Mean FGSI was lower in survivors in comparison with nonsurvivors (5.00 ± 1.86 and 10.00 ± 1.27, respectively; P < 0.001). We conclude that FGSI is an important predictor in the prognosis of FG. Vacuum-assisted closure (VAC) should be performed in compliant patients in order to enhance patient comfort by reducing pain and the number of dressings. Fecal diversion should be performed as needed, preferably by using FMS. The trephine ostomy should be the method of choice in cases where an ostomy is necessary. PMID:25859652

  12. The drug-target residence time model: a 10-year retrospective.

    PubMed

    Copeland, Robert A

    2016-02-01

    The drug-target residence time model was first introduced in 2006 and has been broadly adopted across the chemical biology, biotechnology and pharmaceutical communities. While traditional in vitro methods view drug-target interactions exclusively in terms of equilibrium affinity, the residence time model takes into account the conformational dynamics of target macromolecules that affect drug binding and dissociation. The key tenet of this model is that the lifetime (or residence time) of the binary drug-target complex, and not the binding affinity per se, dictates much of the in vivo pharmacological activity. Here, this model is revisited and key applications of it over the past 10 years are highlighted.

  13. Elective treatment of bleeding varices with the Sugiura operation over 10 years.

    PubMed

    Orozco, H; Mercado, M A; Takahashi, T; Hernández-Ortiz, J; Capellán, J F; Garcia-Tsao, G

    1992-06-01

    A 10-year experience with the devascularization operation described by Sugiura is reported here. The operation was performed electively in 100 patients in whom it was not possible to place a shunt, all of whom had different kinds of hepatopathies (63 Child's A, 32 Child's B, and 5 Child's C). In 15 patients, the procedure was done in one stage (6% operative mortality, 1 patient), and, in 51, it was performed in two stages. Eight deaths were recorded in the 63 patients of the Child's A group, with a total of 111 operations. The operative mortality rate for this group was 12% and, as related to the number of operative procedures, 7% (8 of 111 operations). Seventeen patients were not considered for a second stage. Rebleeding in the early postoperative period was 4% and at long-term 6%. Incapacitating encephalopathy was found in 2 of the 71 surviving patients (3%). Survival (as determined by Kaplan-Meier tests) was 75% (1 year), 70% (5 years), and 69.2% (10 years). Six esophageal fistulas were observed secondary to transection. The Sugiura operation is an excellent complement to the therapeutic armamentarium used to treat portal hypertension, with low rebleeding and encephalopathy rates.

  14. Post-Test Analysis of a 10-Year Sodium Heat Pipe Life Test

    NASA Technical Reports Server (NTRS)

    Rosenfeld, John H.; Locci, Ivan E.; Sanzi, James L.; Hull, David R.; Geng, Steven M.

    2011-01-01

    High-temperature heat pipes are being evaluated for use in energy conversion applications such as fuel cells, gas turbine re-combustors, Stirling cycle heat sources; and with the resurgence of space nuclear power both as reactor heat removal elements and as radiator elements. Long operating life and reliable performance are critical requirements for these applications. Accordingly, long-term materials compatibility is being evaluated through the use of high-temperature life test heat pipes. Thermacore, Inc., has carried out a sodium heat pipe 10-year life test to establish long-term operating reliability. Sodium heat pipes have demonstrated favorable materials compatibility and heat transport characteristics at high operating temperatures in air over long time periods. A representative one-tenth segment Stirling Space Power Converter heat pipe with an Inconel 718 envelope and a stainless steel screen wick has operated for over 87,000 hr (10 years) at nearly 700 C. These life test results have demonstrated the potential for high-temperature heat pipes to serve as reliable energy conversion system components for power applications that require long operating lifetime with high reliability. Detailed design specifications, operating history, and post-test analysis of the heat pipe and sodium working fluid are described. Lessons learned and future life test plans are also discussed.

  15. A 10-year Review of the Clinical Presentation and Treatment Outcome of Asherman's Syndrome at a Center with Limited Resources

    PubMed Central

    Takai, IU; Kwayabura, AS; Ugwa, EA; Idrissa, A; Obed, JY; Bukar, M

    2015-01-01

    Background: Many women suffer from some degree of intrauterine adhesions (IUAs) presenting with various clinical symptoms and signs. Hysteroscopy is the mainstay of diagnosis, classification, and treatment of the IUA. Aim: This study was undertaken to review the clinical features and treatment outcome in patients diagnosed with Asherman's syndrome at the University of Maiduguri Teaching Hospital (UMTH), Maiduguri, over a 10 years period, 1997–2006. Subjects and Methods: This is a retrospective study of cases of Asherman's syndrome managed at the UMTH over a 10-year period, from January 1, 1997 to December 31, 2006. Case records of the patients were retrieved from medical records' Department. Sociodemographic and clinical information relating to clinical presentations, treatment modalities, and outcomes were collated. The data were analyzed using SPSS 16.0 Statistical Computer Package (SPSS Inc., IL, USA 2006). Chi-square and binary logistic regression were used for inferential statistics. Results: Asherman's syndrome constituted 8.1% (81/996) of all gynecological operations in UMTH during the study period. The case records retrieval rate was 96.3% (78/81 folders). Most of the patients, 59% (46/78) were in their third decade and majority 85.9% (67/78) were married. The most common risk factor was pregnancy-associated, accounting for 61.5% (48/78). Infertility and hypomenorrhea were the most common mode of presentations in 55.1% (43/78) and 32.1% (25/78) of cases, respectively. Most of the patients 85.9% (67/78) were treated by blind dilatation and curettage (D/C), Foley's catheter insertion and estrogen-progesterone combination. Correction of menses was seen in 37.2% (29/78) of the patients while the pregnancy rate was 32.1% (25/78). On binary logistic regression age of the respondents, multigravidity, and previous pelvic surgeries for pregnancy (C/S and D/C for abortion) emerged as the only respondent's related risk factors associated with the development of

  16. The Next 10 Years in Voice Evaluation and Treatment.

    PubMed

    Barkmeier-Kraemer, Julie M; Patel, Rita R

    2016-08-01

    Voice disorders are thought to affect approximately one third of all individuals within the United States during their lifetime. Individuals who require the use of their voice as part of their occupations are at highest risk for developing voice problems. Unfortunately, efficient diagnosis and effective management of voice disorders can be challenged by difficulty accessing professionals with the necessary expertise to diagnose and treat voice problems efficiently. Within the next decade, technological advancements show promise for improving the efficiency and effectiveness of intervention for voice disorders. Exciting developments in laryngeal imaging, modeling of patient-specific vocal patterns, and implementation of smart mobile technology and telehealth will greatly improve the accuracy of diagnosing voice problems and enhance implementation and carryover of effective voice treatment methods to daily communication demands. PMID:27232091

  17. Prostate cancer treated with HIFU: A 10-year experience

    NASA Astrophysics Data System (ADS)

    Chapelon, Jean-Yves; Curiel, Laura; Gelet, Albert

    2001-05-01

    Objectives: To evaluate our overall experience in HIFU in the prostate cancer application, for its two main indications: as a primary care and as a salvage therapy after radiation. Material and method: Group 1: patients treated with HIFU as primary care for localized prostate cancer, with a baseline PSA level lower than 30 ng/ml, and with at least 1 year of follow-up were included in this analysis. Group 2: patients with a local recurrence after radiation. They were all treated using the Ablatherm HIFU device (EDAP S.A., France). Results: Group 1: n=242 patients. The mean nadir PSA was 0.63 sd 1.30 ng/ml, and further follow-up evidenced a 81% negative biopsy rate. These results are influenced by the usual prognostic factors (clinical stage, baseline PSA, Gleason score), and, as for the other treatment option, the nadir allows prediction of the patient outcome. Group 2: n=71 patients. After HIFU treatment, 80% of the patients presented negative biopsies, and 61% had a nadir PSA level lower than 0.5 ng/ml, obtained within 3 months. No rectal injury occurred since the use of specific parameters. Conclusion: Transrectal HIFU is a valuable option for prostate cancer, for primary care as well as for salvage therapy.

  18. Management of inguinal hernia in premature infants: 10-year experience

    PubMed Central

    Crankson, Stanley John; Al Tawil, Khalil; Al Namshan, Mohammad; Al Jadaan, Saud; Baylon, Beverly Jane; Gieballa, Mutaz; Ahmed, Ibrahim Hakim

    2015-01-01

    Aim: Debatable issues in the management of inguinal hernia in premature infants remain unresolved. This study reviews our experience in the management of inguinal hernia in premature infants. Materials and Methods: Retrospective chart review of premature infants with inguinal hernia from 1999 to 2009. Infants were grouped into 2: Group 1 had repair (HR) just before discharge from the neonatal intensive care unit (NICU) and Group 2 after discharge. Results: Eighty four premature infants were identified. None of 23 infants in Group 1 developed incarcerated hernia while waiting for repair. Of the 61 infants in Group 2, 47 (77%) underwent day surgery repair and 14 were admitted for repair. At repair mean postconceptional age (PCA) in Group1 was 39.5 ± 3.05 weeks. Mean PCA in Group 2 was 66.5 ± 42.73 weeks for day surgery infants and 47.03 ± 8.87 weeks for admitted infants. None of the 84 infants had an episode of postoperative apnea. Five (5.9%) infants presented subsequently with metachronous contralateral hernia and the same number of infants had hernia recurrence. Conclusions: Delaying HR in premature infants until ready for discharge from the NICU allows for repair closer to term without increasing the risk of incarceration. Because of low occurrence of metachronous hernia contralateral inguinal exploration is not justified. Day surgery HR can be performed in former premature infant if PCA is >47 weeks without increasing postoperative complications. PMID:25552826

  19. Diagnosis and treatment of acute urogenital and genitalia tract traumas: 10-year clinical experience

    PubMed Central

    Zou, Qingsong; Fu, Qiang

    2015-01-01

    Objective: To report our 10-year diagnosis and treatment experience of acute urogenital and genitalia tract traumas and outline the management of the traumatic injury. Methods: We reviewed the diagnoses and treatments of 208 cases of acute kidney, ureter, bladder, urethra, or male genitalia injuries in our department between March 2002 and March 2012. The patient data including general information, injury position and mechanism, diagnosis and treatment, the follow-up information was analyzed and summarized. Results: Of 62 patients with renal injury examined by ultrasound and computed tomography (CT) examination, 45 were treated conservatively, 9 with superselective arterial embolization, and 8 with nephrectomy. Intravenous pyelogram (IVP) was conducted in two patients with ureteral injury, one was treated with cystoscopic ureteral catheterization and the other with ureteric reimplantation. Bladder injury (6 patients) confirmed with a waterflood susceptibility test combined with CT scans underwent laparotomy and the bladder suturing was done. Of 92 patients with urethral injury, 6 were treated with a nonoperative approach (indwelling catheter), 18 with urethral realignment, 35 with cystoscopic urethral realignment, 29 with end-to-end anastomotic urethroplasty, and 4 with urethral repairmen. Of the 24 cases with penile injuries, 1 underwent conservative treatment, 8 were treated with debridement and suture ligation, and 15 were managed with suture repair of the penis white membrane. Of the 24 cases with penile injuries, 1 underwent conservative treatment, 8 were treated with debridement and suture ligation, and 15 were managed with suture repair of the penis white membrane. During the follow-up period, 62 patients with renal injury had normal renal function. Neither of the two patients with ureteral injury developed hydronephrosis. Twenty-nine patients with urethral injury suffered from urethral structure. All patients with vesical or genital injury recovered

  20. Incidental Diagnosis of Filariasis in Superficial Location by FNAC: A Retrospective Study of 10 Years

    PubMed Central

    Khare, Pratima; Jha, Aditi; Chauhan, Nidhi; Chand, Priyanka

    2014-01-01

    Background: Filariasis, transmitted by the bite of various species of mosquito, is a common disease of tropical belt of the world. In South East Asia, including India, it is a major public health problem. The parasite is primarily confined to Lymphatic channel or lymph nodes where it can remain viable for more than two decades. The most common presentation of the disease is asymptomatic/ subclinical microfilaremia, Hydrocele, acute adeno-lymphangitis (ADL) and chronic lymphatic disease. However, the disease may rarely present as superficial swellings at unusual sites. Incidental findings of microfilaria on fine needle aspiration cytology in these situations, helps in prompt recognition of the disease. Aim: The aim of this retrospective study was to assess the incidental diagnosis of Filariasis on fine needle aspiration cytology (FNAC), done for swellings in superficial locations over last ten years at our institute. Materials and Methods: This retrospective study was conducted over a period of 10 years from April 2003 to March 2013 on the cases where FNAC was carried out on swellings in superficial locations of the body. Twenty cases of filariasis were diagnosed on routine FNAC material obtained from various superficial sites. Their data was retrieved and analyzed. Results: Among the 20 cases diagnosed as filariasis on FNAC, six cases involved lymph nodes, six involved testiculo-scrotal region, three cases of thyroid swelling, soft tissue swelling in three cases and breast lump in two cases. On FNA smears, microfilariae were seen in all 20 cases, eggs in three cases, adult female worm in two cases and adult male worm in one case. Adherence of inflammatory cells and macrophages to microfilariae was noticed in 4 cases. Eosinophilia was present in seven cases. Microfilaremia was present in only three cases. Causative agent was Wuchereria bancrofti in all cases. Conclusion: Although not so common, filariasis should be considered as one of the differential diagnosis of

  1. Emphysematous pyelonephritis: A 10-year experience with 26 cases

    PubMed Central

    Misgar, Raiz Ahmad; Mubarik, Idrees; Wani, Arshad Iqbal; Bashir, Mir Iftikhar; Ramzan, Mahroosa; Laway, Bashir Ahmad

    2016-01-01

    Background: Emphysematous pyelonephritis (EPN) is a necrotizing infection which results in gas within the renal parenchyma, collecting system, or perinephric tissue. A majority of cases occur in patients with diabetes mellitus (DM). In EPN, early aggressive medical treatment may avoid nephrectomy. Aims: The aim of this study was to analyze the characteristics of patients with EPN with respect to patient demographics, clinical presentation, diagnostic investigations, microbiological findings, treatment modality and outcome, and the influence of prognostic factors on the outcome. Materials and Methods: We reviewed the hospital records of 26 patients with EPN for clinical, laboratory, radiological, and microbiological findings, treatments given, and outcome. The severity of EPN was graded as per the Huang classification. We applied the reported prognostic factors to our patients to find out whether these factors correlated with failure of conservative treatment. Results: All the study subjects had DM and all but two of them were females. The majority of our patients (61.5%) had extensive EPN (class 3 or 4) and majority (76.9%) had two or more bad prognostic factors. Escherichia coli was the most common causative organism involved in 50% of our cases. Twenty-three (88.5%) of our patients responded to conservative treatment, two required nephrectomy, and one expired on conservative treatment. Conclusions: In this series of patients with EPN, all had DM, nearly all were women, and E. coli was the most frequently isolated pathogen. Nearly a third of our patients had bilateral disease. Despite the presence of two or more bad prognostic factors and extensive EPN (class 3 or 4) in a majority of our patients, conservative treatment afforded a striking success rate of 88.5%. We recommend early aggressive medical treatment and suggest that nephrectomy should be considered only if patients deteriorate or do not improve on conservative treatment. PMID:27366713

  2. Pediatric flexor tendon injuries: A 10-year outcome analysis

    PubMed Central

    Sikora, Sheena; Lai, Michelle; Arneja, Jugpal S

    2013-01-01

    BACKGROUND: Primary flexor tendon repair was first introduced in the 1960s. Since then, major advances in the understanding of flexor tendon anatomy and biology have led to improved outcomes following repair. Relative to the adult population, sparse knowledge exists as to which operative and postoperative treatments are most successful in children. This is due, in part, to the rarity of pediatric tendon lacerations compared with the adult population, but also related to challenges when working with smaller anatomy and the decreased compliance in children with respect to rehabilitation protocols. Published reports indicate that the incidence of ‘good’ flexor tendon repair outcomes is as low as 53%. OBJECTIVE: To determine the injury pattern and demographics of pediatric flexor tendon injuries involving zones I, II and III over the past decade, and to report results and identify treatment paradigms that are associated with optimal outcomes. METHODS: A retrospective chart review of all flexor tendon injuries involving zones I, II and III between April 2001 and December 2010 was performed. Parameters reviewed included demographics, injury mechanism, repair technique, outcomes and complications. RESULTS: A total of 47 patients with a median age of eight years experienced 100 tendon injuries. The most common cause of injury was glass (n=22), with the most common digit injured being the small finger (n=30). Tendon injuries included the following: flexor digitorum superficialis (n=46); flexor digitorum profundus (n=45), flexor pollicis longus (n=8); and adductor pollicis longus (n=1). Zone III had the highest number of injuries (n=47), followed by zone II (n=39). Ninety tendons were repaired using polyester suture, the most common size being 4-0. The modified Kessler technique was used in the majority of cases (n=62). Only 22 tendons underwent an epitendinous repair. Splint immobilization was used in 30 patients and a full cast in 17. The median duration of

  3. The Effects of Lack of Joint Goal Planning on Divorce over 10 Years

    PubMed Central

    Gere, Judith; Almeida, David M.; Martire, Lynn M.

    2016-01-01

    Given the negative consequences of divorce on health and well-being, it is important to try to identify its predictors. In the current study we used data from the National Survey of Midlife Development (N = 2801) to examine the longitudinal effects of lack of joint goal planning with a romantic relationship partner on divorce over a 10-year period. Multilevel regression analyses showed that lack of joint planning with the relationship partner was associated with a 19% increase in the odds of divorce, even when controlling for various demographic (i.e., age, gender, relationship length, number of children in the household), individual (i.e., neuroticism, positive affect, negative affect, physical symptoms, planning), and relationship (i.e., marital empathy, partner strain, partner disagreement, marital satisfaction, commitment). These results demonstrate the importance of considering one’s partner when making decisions and plans for the future, given that it has clear implications for relationship dissolution. PMID:27668863

  4. Health Care Finance Executive Personalities Revisited: A 10-Year Follow-up Study.

    PubMed

    Lieneck, Cristian; Nowicki, Michael

    2015-01-01

    A dynamic health care industry continues to call upon health care leaders to possess not one but multiple competencies. Inherent personality characteristics of leaders often play a major role in personal as well as organizational success to include those in health care finance positions of responsibility. A replication study was conducted to determine the Myers-Briggs personality-type differences between practicing health care finance professionals in 2014, as compared with a previous 2003 study. Results indicate a significant shift between both independent samples of health care finance professionals over the 10-year period from original high levels of introversion to that of extraversion, as well as higher sensing personality preferences, as compared with the original sample's high level of intuition preferences. Further investigation into the evolving role of the health care finance manager is suggested, while continued alignment of inherent, personal characteristics is suggested to meet ongoing changes in the industry.

  5. From Exotic to Mainstream: A 10-year Odyssey from Internet Speed to Boundary Spanning with Scrum

    NASA Astrophysics Data System (ADS)

    Baskerville, Richard; Pries-Heje, Jan; Madsen, Sabine

    Based on four empirical studies conducted over a 10-year time period from 1999 to 2008 we investigate how local software processes interact with global changes in the software development context. In 1999 companies were developing software at high speed in a desperate rush to be first-to-market. In 2001 a new high speed/quick results development process had become established practice. In 2003 changes in the market created the need for a more balanced view on speed and quality, and in 2008 companies were successfully combining agile and plan driven approaches to achieve the benefits of both. The studies reveal a twostage pattern in which dramatic changes in the market causes disruption of established practices, experimentation, and process adaptations followed by consolidation of lessons learnt into a new (and once again mature) software development process. Limitations, implications, and areas for future research are discussed.

  6. Tuberculosis in Israel: a 10-year survey of an immigrant society.

    PubMed

    Dolberg, O T; Alkan, M; Schlaeffer, F

    1991-07-01

    Over a 10-year period (1978-87), 279 tuberculosis (TB) patients were diagnosed at the Soroka Medical Center. Of these, 48% were Ethiopian Jews, 28% Bedouin Arabs, and 24% were Jews of other origins. The Bedouin and Ethiopian patients were younger and had fewer concomitant diseases. The Ethiopian patients were hospitalized longer than other patients. Ethiopian and Bedouin patients were less compliant with therapy. There were 187 cases of pulmonary TB (67%), and 92 cases of extrapulmonary TB (33%). The majority of the Bedouin and Ethiopian patients had pulmonary tuberculosis, while extrapulmonary TB was more frequent among the rest of the patients. It is concluded that TB in the Negev reflects the diversity of its population, with characteristics of both a developing and a developed country. PMID:2071375

  7. Trends in Cardiovascular Disease Risk Factor Prevalence and Estimated 10-Year Cardiovascular Risk Scores in a Large Untreated French Urban Population: The CARVAR 92 Study

    PubMed Central

    Karam, Carma; Beauchet, Alain; Czernichow, Sebastien; de Roquefeuil, Florence; Bourez, Alain; Mansencal, Nicolas; Dubourg, Olivier

    2015-01-01

    Background Surveys measuring effectiveness of public awareness campaigns in reducing cardiovascular disease (CVD) incidence have yielded equivocal findings. The aim of this study was to describe cardiovascular risk factors (CVRFs) changes over the years in an untreated population-based study. Methods Between 2007 and 2012, we conducted a screening campaign for CVRFs in men aged 40 to 65 yrs and women aged 50 to 70 yrs in the western suburbs of Paris. Data were complete for 20,324 participants of which 14,709 were untreated. Results The prevalence trend over six years was statistically significant for hypertension in men from 25.9% in 2007 to 21.1% in 2012 (p=0.002) and from 23% in 2007 to 12.7% in 2012 in women (p<0.0001). The prevalence trend of tobacco smoking decreased from 38.6% to 27.7% in men (p=0.0001) and from 22.6% to 16.8% in women (p=0.113). The Framingham 10-year risk for CVD decreased from 13.3 ± 8.2 % in 2007 to 11.7 ± 9.0 % in 2012 in men and from 8.0 ± 4.1 % to 5.9 ± 3.4 % in women. The 10-year risk of fatal CVD based on the European Systematic COronary Risk Evaluation (SCORE) decreased in men and in women (p <0.0001). Conclusions Over a 6-year period, several CVRFs have decreased in our screening campaign, leading to decrease in the 10-year risk for CVD and the 10-year risk of fatal CVD. Cardiologists should recognize the importance of community prevention programs and communication policies, particularly tobacco control and healthier diets to decrease the CVRFs in the general population. PMID:25906186

  8. Period analysis of hydrologic series through moving-window correlation analysis method

    NASA Astrophysics Data System (ADS)

    Xie, Yangyang; Huang, Qiang; Chang, Jianxia; Liu, Saiyan; Wang, Yimin

    2016-07-01

    Period analysis is of great significance for understanding various hydrologic processes and predicting the future hydrological regime of a watershed or region. Hence, many period analysis methods including fast Fourier transform (FFT), maximum entropy spectral analysis (MESA) and wavelet analysis (WA) have been developed to study this issue. However, due to the complex components of hydrologic series and the limitations of these conventional methods, the problem is still difficult to be solved. In this paper, the moving-window correlation analysis method (MWCA) has been proposed for analyzing the periodic component of hydrologic series, which includes construction of periodic processes, significant test of periods and time frequency analysis. Three commonly used methods (FFT, MESA and WA) and MWCA are employed to investigate the periods of synthetic series and observed hydrologic series, respectively. The results show that FFT, MESA and WA are not always as good as expected when detecting periods of a time series. By contrast, MWCA has better application effects, which could identify the true periods of time series, extract the reliable periodic components, find the active time ranges of periodic components and resist the disturbance of noises. In conclusion, MWCA is suitable to identify the true periods of hydrologic time series.

  9. Injuries in a Professional Ballet Dance Company: A 10-year Retrospective Study.

    PubMed

    Ramkumar, Prem N; Farber, Joseph; Arnouk, Johnny; Varner, Kevin E; Mcculloch, Patrick C

    2016-03-01

    Ballet dancers are high-performance athletes who are particularly susceptible to a wide variety of musculoskeletal injuries. However, they are relatively understudied, and data on their injury rates are lacking. This retrospective study features the largest aggregate data on professional ballet dancers to date and aims to identify the most common diagnoses and areas of injury in this unique population to better direct preventative and clinical practices. The study encompassed a 10-year period from January 2000 to December 2010 of dancers from a single company. Data regarding the dancers' age, gender, location of injury, and diagnosis were collected from workers' compensation claims, company records, and medical records maintained by the treating doctors. These were analyzed to determine metrics on injury incidence, frequency, and diagnosis. Over the 10-year span, 574 injuries occurred. There were approximately 52 dancers per year for a total of 153 who danced at least one complete season during the study period. The average age was 27, and 53% were female. Given turnover with retirement and replacements, the total number of dancer-years was 520, indicating an injury incidence per annum of 1.10 (574 injuries per 520 dancer-years). The most common locations of injury were foot and ankle and the lumbar spine, with the three most common diagnoses making up greater than a third (37%) of the total. As the current largest study in professional ballet, the findings set the benchmark metrics for musculoskeletal injury to the foot, ankle, and lumbar spine sites. Future studies should aim to identify injury risk factors and modalities for prevention of these injuries. PMID:27025450

  10. Deaths in the Cook County jail: 10-year report, 1995-2004.

    PubMed

    Kim, Seijeoung; Ting, Andrew; Puisis, Michael; Rodriguez, Sergio; Benson, Roger; Mennella, Connie; Davis, Faith

    2007-01-01

    The aims of this study were to describe causes of death during the 10-year period between 1995 and 2004 in a large urban jail in Chicago; to compare disease specific mortality rates between the jail population and the general population; to explore demographic and incarceration characteristics of the inmates who died in the jail by cause of death; and to examine gender difference in demographic characteristics, incarceration patterns, and causes of death. A total of 178 deaths occurring in the jail over a 10-year period (1995-2004) were reviewed. Age-adjusted disease-specific mortality rates were computed for the jail population and compared with the rates in the US general population. Cause of death, demographic variables, and incarceration related factors were retrieved from multiple computerized databases. Descriptive analyses were performed to examine demographic and incarceration-related patterns by cause of death and gender. Heart disease was the most frequent cause of death in the jail population, followed by cerebrovascular disease and suicide. Mortality rates for heart diseases, infectious/inflammatory conditions and suicide were higher for jail inmates than the general population. Black inmates accounted for the majority of deaths due to illnesses and homicide, and a much higher proportion of white and Hispanic inmates were involved in suicide deaths. Deaths due to drug overdose or withdrawal were disproportionately higher among female inmates compared with male inmates. Consistent review of mortality rates and causes of deaths in jail can be a useful tool to better understand health issues and needs of jail inmates. Surveillance of acute and chronic illnesses and strategic reengineering of jail health care is a key to quality improvement for incarcerated populations for whom the jail system becomes their primary care provider. PMID:17136629

  11. Injuries in a Professional Ballet Dance Company: A 10-year Retrospective Study.

    PubMed

    Ramkumar, Prem N; Farber, Joseph; Arnouk, Johnny; Varner, Kevin E; Mcculloch, Patrick C

    2016-03-01

    Ballet dancers are high-performance athletes who are particularly susceptible to a wide variety of musculoskeletal injuries. However, they are relatively understudied, and data on their injury rates are lacking. This retrospective study features the largest aggregate data on professional ballet dancers to date and aims to identify the most common diagnoses and areas of injury in this unique population to better direct preventative and clinical practices. The study encompassed a 10-year period from January 2000 to December 2010 of dancers from a single company. Data regarding the dancers' age, gender, location of injury, and diagnosis were collected from workers' compensation claims, company records, and medical records maintained by the treating doctors. These were analyzed to determine metrics on injury incidence, frequency, and diagnosis. Over the 10-year span, 574 injuries occurred. There were approximately 52 dancers per year for a total of 153 who danced at least one complete season during the study period. The average age was 27, and 53% were female. Given turnover with retirement and replacements, the total number of dancer-years was 520, indicating an injury incidence per annum of 1.10 (574 injuries per 520 dancer-years). The most common locations of injury were foot and ankle and the lumbar spine, with the three most common diagnoses making up greater than a third (37%) of the total. As the current largest study in professional ballet, the findings set the benchmark metrics for musculoskeletal injury to the foot, ankle, and lumbar spine sites. Future studies should aim to identify injury risk factors and modalities for prevention of these injuries.

  12. Energy Expansion for the Period of Anharmonic Oscillators by the Method of Lindstedt-Poincare

    ERIC Educational Resources Information Center

    Fernandez, Francisco M.

    2004-01-01

    A simple, straightforward and efficient method is proposed for the calculation of the period of anharmonic oscillators as an energy series. The approach is based on perturbation theory and the method of Lindstedt-Poincare.

  13. A 10-year prognostic model for patients with suspected angina attending a chest pain clinic

    PubMed Central

    Sekhri, Neha; Perel, Pablo; Clayton, Tim; Feder, Gene S; Hemingway, Harry; Timmis, Adam

    2016-01-01

    Background and objective Diagnostic models used in the management of suspected angina provide no explicit information about prognosis. We present a new prognostic model of 10-year coronary mortality in patients presenting for the first time with suspected angina to complement the Diamond-Forrester diagnostic model of disease probability. Methods and results A multicentre cohort of 8762 patients with suspected angina was followed up for a median of 10 years during which 233 coronary deaths were observed. Developmental (n=4412) and validation (n=4350) prognostic models based on clinical data available at first presentation showed good performance with close agreement and the final model utilised all 8762 patients to maximise power. The prognostic model showed strong associations with coronary mortality for age, sex, chest pain typicality, smoking status, diabetes, pulse rate, and ECG findings. Model discrimination was good (C statistic 0.83), patients in the highest risk quarter accounting for 173 coronary deaths (10-year risk of death: 8.7%) compared with a total of 60 deaths in the three lower risk quarters. When the model was simplified to incorporate only Diamond-Forrester factors (age, sex and character of symptoms) it underestimated coronary mortality risk, particularly in patients with reversible risk factors. Conclusions For the first time in patients with suspected angina, a prognostic model is presented based on simple clinical factors available at the initial cardiological assessment. The model discriminated powerfully between patients at high risk and lower risk of coronary death during 10-year follow-up. Clinical utility was reflected in the prognostic value it added to the updated Diamond-Forrester diagnostic model of disease probability. PMID:26928409

  14. Natrelle Round Silicone Breast Implants: Core Study Results at 10 Years

    PubMed Central

    Murphy, Diane K.

    2014-01-01

    Background: Allergan’s Natrelle round silicone-filled breast implants were approved by the U.S. Food and Drug Administration in 2006 based on interim results from the Core Study; final 10-year study results are now available. Methods: Seven hundred fifteen subjects were implanted with smooth and Biocell textured Natrelle round silicone implants and attended clinic visits at 0 to 4 weeks, 6 months, 1 year, and annually through 10 years. Approximately one-third of subjects underwent magnetic resonance imaging at years 1, 3, 5, 7, and 9 to assess rupture. Results: Complication rates showed modest increases over the previously published 6-year rates. The Kaplan-Meier capsular contracture rate was 18.9 percent for augmentation, 28.7 percent for revision-augmentation, and 24.6 percent for reconstruction. Among augmentation subjects, capsular contracture was significantly lower (p = 0.023) for submuscular (15.7 percent) versus subglandular (26.3 percent) placement. The overall rupture rate in the magnetic resonance imaging cohort was 13.0 percent for subjects and 7.7 percent for implants. By the end of the study, 81.8 percent of augmentation subjects still had an original implant in place. Using a five-point scale, 94.2 percent of augmentation, 83.8 percent of revision-augmentation, and 90.7 percent of reconstruction subjects reported being satisfied or definitely satisfied with their implants. Significant improvement over baseline was also seen in overall breast satisfaction and satisfaction with breast size, shape, feel, and how well they matched. Conclusion: The 10-year data from the Natrelle Core Study, which can guide surgeons and patients in decision-making, demonstrate safety and high levels of patient satisfaction. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III. PMID:24867717

  15. A sampling method for the reconstruction of a periodic interface in a layered medium

    NASA Astrophysics Data System (ADS)

    Sun, Guanying; Zhang, Ruming

    2016-07-01

    In this paper, we consider the inverse problem of reconstructing periodic interfaces in a two-layered medium with TM-mode. We propose a sampling-type method to recover the top periodic interface from the near-field data measured on a straight line above the total structure. Finally, numerical experiments are illustrated to show the effectiveness of the method.

  16. An improved correlation method for determining the period of a torsion pendulum

    SciTech Connect

    Luo Jie; Wang Dianhong

    2008-09-15

    Considering variation of environment temperature and unhomogeneity of background gravitational field, an improved correlation method was proposed to determine the variational period of a torsion pendulum with high precision. The result of processing experimental data shows that the uncertainty of determining the period with this method has been improved about twofolds than traditional correlation method, which is significant for the determination of gravitational constant with time-of-swing method.

  17. An improved correlation method for determining the period of a torsion pendulum.

    PubMed

    Luo, Jie; Wang, Dian-Hong

    2008-09-01

    Considering variation of environment temperature and unhomogeneity of background gravitational field, an improved correlation method was proposed to determine the variational period of a torsion pendulum with high precision. The result of processing experimental data shows that the uncertainty of determining the period with this method has been improved about twofolds than traditional correlation method, which is significant for the determination of gravitational constant with time-of-swing method.

  18. Spatiotemporal Trends Analysis of Pyrethroid Sediment Concentrations Spanning 10 Years in a Residential Creek in California.

    PubMed

    Hall, Lenwood W; Anderson, Ronald D; Killen, William D

    2016-02-01

    The objective of this study was to assess temporal and spatial trends for eight pyrethroids monitored in sediment spanning 10 years from 2006 to 2015 in a residential stream in California (Pleasant Grove Creek). The timeframe for this study included sampling 3 years during a somewhat normal non-drought period (2006-2008) and 3 years during a severe drought period (2013-2015). Regression analysis of pyrethroid concentrations in Pleasant Grove Creek for 2006, 2007, 2008, 2012, 2013, 2014, and 2015 using ½ the detection limit for nondetected concentrations showed statistically significant declining trends for cyfluthrin, cypermethrin, deltamethrin, permethrin, and total pyrethoids. Additional trends analysis of the Pleasant Grove Creek pyrethroid data using only measured concentrations, without nondetected values, showed similar statistically significant declining trends for cyfluthrin, cypermethrin, deltamethrin, esfenvalerate, fenpropathrin, permethrin, and total pyrethroids. Spatial trends analysis for the specific creek sites showed that six of the eight pyrethroids had a greater number of sites with statistically significant declining concentrations. Possible reasons for reduced pyrethroid concentrations in the stream bed in Pleasant Grove Creek during this 10-year period are label changes in 2012 that reduced residential use and lack of precipitation during the later severe drought years of 2013-2015. PMID:26643307

  19. 100% Retention of Snowpack Derived Nitrogen Over 10 Years in High Arctic Tundra

    NASA Astrophysics Data System (ADS)

    Choudhary, S.; Tye, A. M.; Young, S. D.; West, H. M.; Phoenix, G. K.

    2013-12-01

    Tundra ecosystems are susceptible to atmospheric nitrogen (N) deposition, increasing as a result of anthropogenic activities as well as climate change. Depositions that get accumulated within the snowpack during winter months are released in spring during snowmelt, providing a periodic input of reactive N in the melt water to such nutrient limited ecosystems. Identifying ecosystem N retention and allocation and how this change over time is important to understanding the long-term consequences of such N depositions to these ecosystems. We reanalysed 10 years later an atmospheric N deposition study established in Svalbard that in 2001 used 15N isotope tracers to determine the fate of N released from melting snowpack. Applications of 15N (99 atom%) at 0.1 and 0.5 g N m-2 were made immediately after snowmelt in 2001 as either Na15NO3 or 15NH4Cl. These applications were approximately 1 × and 5 × the yearly atmospheric deposition rates. In both the previous short-term (one week to two years after 15N tracer application) and our long-term re-sampling (10 years after 15N tracer application), ~67% of the total applied 15N was retained in the ecosystem, irrespective of the N forms or N dose. This meant the tundra had 100% long-term N retention after initial partitioning, suggesting a highly conservative N cycling. Bryophytes, followed by the organic soil horizon and then the microbial biomass formed the greatest short-term 15N sink. Maximum changes in 15N retention from the short- to long-term were observed in the microbial 15N pools, with ~75% of the 15N in soil located in its biomass during the initial partitioning (July 2001) decreasing to ~17% 10 years later. This indicates significant microbial N turnover mostly into stable humus N. In contrast, vascular plants, particularly Salix polaris, showed significant increases (~60%) in their 15N retention after 10 years, indicating a high capacity for acting as a long-term N sink in this tundra ecosystem. Because the largest

  20. Quadrature methods for periodic singular and weakly singular Fredholm integral equations

    NASA Technical Reports Server (NTRS)

    Sidi, Avram; Israeli, Moshe

    1988-01-01

    High-accuracy numerical quadrature methods for integrals of singular periodic functions are proposed. These methods are based on the appropriate Euler-Maclaurin expansions of trapezoidal rule approximations and their extrapolations. They are subsequently used to obtain accurate quadrature methods for the solution of singular and weakly singular Fredholm integral equations. Throughout the development the periodic nature of the problem plays a crucial role. Such periodic equations are used in the solution of planar elliptic boundary value problems such as those that arise in elasticity, potential theory, conformal mapping, and free surface flows. The use of the quadrature methods is demonstrated with numerical examples.

  1. Cannabis use and the course of schizophrenia: 10-year follow-up after first hospitalization

    PubMed Central

    Foti, Daniel J.; Kotov, Roman; Guey, Lin T.; Bromet, Evelyn J.

    2013-01-01

    Objective The authors examined the relationship between cannabis use and the course of illness in schizophrenia over 10 years following first psychiatric hospitalization. Method We assessed 229 patients with a schizophrenia-spectrum disorder five times: during the first admission, and 6 months, 2 years, 4 years, and 10 years later. Ratings of cannabis use and psychiatric symptoms (psychotic, negative, disorganized, and depressive) were made at each assessment. Results The lifetime rate of cannabis use was 66.2%, and survival analysis revealed that this usage was associated with an earlier onset of psychosis. The rates of current use ranged from 10% to 18% across assessments. Cannabis status was moderately stable, with concordance between waves ranging rtet = 0.48 – 0.78. Mixed-effects logistic regression revealed that changes in cannabis use were associated with changes in psychotic symptoms over time even after gender, age, socio-economic status, other drug use, antipsychotic medication use, and other symptoms were controlled. Structural equation modeling indicated that the association with psychotic symptoms was bi-directional. Conclusions Cannabis use is associated with an adverse course of psychotic symptoms in schizophrenia, and vice versa, even after taking into account other clinical, substance, and demographic variables. The specificity of this relationship suggests that clinical interventions to reduce cannabis use may be best targeted at individuals with prominent psychotic symptoms. PMID:20478874

  2. Bibliometric Analysis of Orthopedic Literature on Total Knee Arthroplasty in Asian Countries: A 10-year Analysis

    PubMed Central

    Eom, Sang Hwa; Bamne, Ankur B.; Chowdhry, Madhav; Chae, Ihn Seok

    2015-01-01

    Purpose We aimed to determine the quantity and quality of research output of selected Asian countries in the field of total knee arthroplasty (TKA) in the last 10 years. Materials and Methods Top 15 Asian countries were selected according to their gross domestic product. The Science Citation Index Expanded database was used to search for the literature published between 2004 and 2013 using "Total Knee Arthroplasty". The numbers of articles, journals and citations and the contribution of each country were analyzed. The articles were classified according to the type of study and the relative proportion of each type was analyzed. Results Asian surgeons have increasingly contributed to orthopedic literature on TKA for the past 10 years, but the dominant contribution came from only a few countries. The total number of articles published by Asian countries increased by 261%, with Japan producing most of the studies and China showing the maximum growth rate. The majority of studies were published in low impact factor journals. Korea published the highest proportion of articles in high impact factor journals. Clinical papers were most frequent. Conclusions Our identification of research productivity pertaining to TKA among Asian countries gives a unique insight into the level of academic research in the field of TKA in these countries. There is a need to improve the quality of research to enhance the publishing power in high impact journals as well as the need for more basic research and epidemiological studies considering the unique differences among Asian patients undergoing TKA. PMID:26389067

  3. Particle mesh Ewald method for three-dimensional systems with two-dimensional periodicity

    NASA Astrophysics Data System (ADS)

    Kawata, Masaaki; Nagashima, Umpei

    2001-05-01

    A particle mesh Ewald method for calculating Coulomb interactions in three-dimensional (3D) systems with two-dimensional (2D) periodicity was developed. Computational efficiency and accuracy of this method were evaluated for a TIP3P water system with 2928 particles in a cubic box with 2D periodicity. The accuracy of this method for calculating Coulomb interactions is comparable to our previous method that uses Fourier integral. For calculations with maximum errors in the Coulomb force of 0.4- 20.0 kJ mol -1 nm-1, the current method was up to five times faster than the previous method.

  4. Changes in Neuropsychological Functioning over 10 Years Following Adolescent Substance Abuse Treatment

    PubMed Central

    Hanson, Karen L.; Cummins, Kevin; Tapert, Susan F.; Brown, Sandra A.

    2011-01-01

    Previously, Anderson, Ramo, Cummins, and Brown (2010) described six distinct patterns of alcohol and other drug (AOD) use during the decade following adolescents’ treatment for alcohol and other substance use disorders (A/SUD). This time period represents a phase of significant neurodevelopment and the influence of substance use on the brain is a concern. In the present study we examined patterns of neuropsychological function over these 10 years in relation to the AOD trajectories identified for youth as they transition into their twenties. Participants were part of a longitudinal research project following adolescents with and without A/SUD who received neuropsychological examinations at baseline and up to 7 times thereafter spanning 10 years (N=213; 46% female at baseline). Neuropsychological trajectories were significantly related to substance involvement patterns over time on measures of verbal learning and memory (ps=.011 to <.0001), visuospatial memory (p=.0002), and verbal attention/working memory (p=.020), with heavier use patterns generally followed by poorer cognition. Heavy use of alcohol alone was independently associated with poorer verbal memory over time. Further, substance withdrawal symptoms during each follow-up time point were related to poorer verbal learning and memory scores (ps<.05), while substance abuse/dependence diagnostic criteria were not related to neuropsychological performance levels. These findings suggest that AOD use during adolescence and young adulthood may primarily influence performance that relies on later maturing brain structures, although further research is needed. Higher levels of AOD withdrawal symptoms may signify greater neuropsychological impairment, reflecting potential neurotoxic effects of AOD use. PMID:21443308

  5. Evaluation of a Hybrid Dynamic Stabilization and Fusion System in the Lumbar Spine: A 10 Year Experience

    PubMed Central

    Kashkoush, Ahmed; Agarwal, Nitin; Paschel, Erin; Goldschmidt, Ezequiel

    2016-01-01

    Introduction: The development of adjacent-segment disease is a recognized consequence of lumbar fusion surgery. Posterior dynamic stabilization, or motion preservation, techniques have been developed which theoretically decrease stress on adjacent segments following fusion. This study presents the experience of using a hybrid dynamic stabilization and fusion construct for degenerative lumbar spine pathology in place of rigid arthrodesis. Methods: A clinical cohort investigation was conducted of 66 consecutive patients (31 female, 35 male; mean age: 53 years, range: 25 – 76 years) who underwent posterior lumbar instrumentation with the Dynesys Transition Optima (DTO) implant (Zimmer-Biomet Spine, Warsaw, IN) hybrid dynamic stabilization and fusion system over a 10-year period. The median length of follow-up was five years. DTO consists of pedicle screw fixation coupled to a rigid rod as well as a flexible longitudinal connecting system. All patients had symptoms of back pain and neurogenic claudication refractory to non-surgical treatment. Patients underwent lumbar arthrodesis surgery in which the hybrid system was used for stabilization instead of arthrodesis of the stenotic adjacent level. Results: Indications for DTO instrumentation were primary degenerative disc disease (n = 52) and failed back surgery syndrome (n = 14). The most common dynamically stabilized and fused segments were L3-L4 (n = 37) and L5-S1 (n = 33), respectively. Thirty-eight patients (56%) underwent decompression at the dynamically stabilized level, and 57 patients (86%) had an interbody device placed at the level of arthrodesis. Complications during the follow-up period included a single case of screw breakage and a single case of pseudoarthrosis. Ten patients (15%) subsequently underwent conversion of the dynamic stabilization portion of their DTO instrumentation to rigid spinal arthrodesis. Conclusion: The DTO system represents a novel hybrid dynamic stabilization and fusion construct

  6. Does Loss of Spasticity Matter? A 10-Year Follow-up after Selective Dorsal Rhizotomy in Cerebral Palsy

    ERIC Educational Resources Information Center

    Tedroff, Kristina; Lowing, Kristina; Jacobson, Dan N. O.; Astrom, Eva

    2011-01-01

    Aim: The aim of this study was to evaluate the long-term effects of selective dorsal rhizotomy (SDR) in children with cerebral palsy (CP). Method: Nineteen children (four females, 15 males; mean age 4y 7mo, SD 1y 7mo) with bilateral spastic CP, were prospectively assessed at baseline and 18 months, 3 years, and 10 years after SDR. Assessments…

  7. VARIABILITY OF LUMINOUS STARS IN THE LARGE MAGELLANIC CLOUD USING 10 YEARS OF ASAS DATA

    SciTech Connect

    Szczygiel, D. M.; Stanek, K. Z.; Bonanos, A. Z.; Pojmanski, G.; Pilecki, B.; Prieto, J. L. E-mail: kstanek@astronomy.ohio-state.ed E-mail: gp@astrouw.edu.p E-mail: jose@obs.carnegiescience.ed

    2010-07-15

    Motivated by the detection of a recent outburst of the massive luminous blue variable LMC-R71, which reached an absolute magnitude M{sub V} = -9.3 mag, we undertook a systematic study of the optical variability of 1268 massive stars in the Large Magellanic Cloud, using a recent catalog by Bonanos et al. as the input. The ASAS All Star Catalog provided well-sampled light curves of these bright stars spanning 10 years. Combining the two catalogs resulted in 599 matches, on which we performed a variability search. We identified 117 variable stars, 38 of which were not known before, despite their brightness and large amplitude of variation. We found 13 periodic stars that we classify as eclipsing binary (EB) stars, 8 of which are newly discovered bright massive EBs composed of OB-type stars. The remaining 104 variables are either semi- or non-periodic, the majority (85) being red supergiants (RSGs). Most (26) of the newly discovered variables in this category are also RSGs with only three B and four O stars.

  8. Aging parents' caregiving and rehabilitating a brain-injured son: an autoethnography of a 10-year journey.

    PubMed

    Hassan, Syed Tajuddin Syed; Jamaludin, Husna

    2014-01-01

    This autoethnography withdraws from information accumulated through a 10-year period of daily-weekly-monthly descriptive observation-recording (triangulated- parents & house-helper) of caregiving and rehabilitating of our brain injured son (survivor/care-receiver). We present it as an interactive voice of verbal conversation, thoughts, insights, and interpretations. It is delivered as a series of articulation intra-pulsated with our interrogation of societal-cultural-religious perspectives, norms and biases, and aligns with the CAP (Creative Analytical Practices) method of Ellis. This autoethnography glows from the richness of information which encapsulates the challenges confronting us the aging parent caregivers, the gradual incremental mind mending achievement of our son, and the interactive verbalizations and thoughts, of the caregivers, care-receiver, and other persons. The overwhelming mental and physical pain and struggle of the survivor and the aging caregivers and their sense of celebratory-satisfaction with rehabilitation progress are highlighted. Interpretation and valuation of positive and negative responses of other persons provide a critical matrix to this autoethnography. We intend to inform other caregivers and relevant healthcare professionals through this autoethnography. PMID:25763170

  9. Aging parents’ caregiving and rehabilitating a brain-injured son: an autoethnography of a 10-year journey

    PubMed Central

    Hassan, Syed Tajuddin Syed; Jamaludin, Husna

    2014-01-01

    This autoethnography withdraws from information accumulated through a 10-year period of daily-weekly-monthly descriptive observation-recording (triangulated- parents & house-helper) of caregiving and rehabilitating of our brain injured son (survivor/care-receiver). We present it as an interactive voice of verbal conversation, thoughts, insights, and interpretations. It is delivered as a series of articulation intra-pulsated with our interrogation of societal-cultural-religious perspectives, norms and biases, and aligns with the CAP (Creative Analytical Practices) method of Ellis. This autoethnography glows from the richness of information which encapsulates the challenges confronting us the aging parent caregivers, the gradual incremental mind mending achievement of our son, and the interactive verbalizations and thoughts, of the caregivers, care-receiver, and other persons. The overwhelming mental and physical pain and struggle of the survivor and the aging caregivers and their sense of celebratory-satisfaction with rehabilitation progress are highlighted. Interpretation and valuation of positive and negative responses of other persons provide a critical matrix to this autoethnography. We intend to inform other caregivers and relevant healthcare professionals through this autoethnography. PMID:25763170

  10. Aging parents' caregiving and rehabilitating a brain-injured son: an autoethnography of a 10-year journey.

    PubMed

    Hassan, Syed Tajuddin Syed; Jamaludin, Husna

    2014-01-01

    This autoethnography withdraws from information accumulated through a 10-year period of daily-weekly-monthly descriptive observation-recording (triangulated- parents & house-helper) of caregiving and rehabilitating of our brain injured son (survivor/care-receiver). We present it as an interactive voice of verbal conversation, thoughts, insights, and interpretations. It is delivered as a series of articulation intra-pulsated with our interrogation of societal-cultural-religious perspectives, norms and biases, and aligns with the CAP (Creative Analytical Practices) method of Ellis. This autoethnography glows from the richness of information which encapsulates the challenges confronting us the aging parent caregivers, the gradual incremental mind mending achievement of our son, and the interactive verbalizations and thoughts, of the caregivers, care-receiver, and other persons. The overwhelming mental and physical pain and struggle of the survivor and the aging caregivers and their sense of celebratory-satisfaction with rehabilitation progress are highlighted. Interpretation and valuation of positive and negative responses of other persons provide a critical matrix to this autoethnography. We intend to inform other caregivers and relevant healthcare professionals through this autoethnography.

  11. Prospects for Emerging Infections in East and Southeast Asia 10 Years after Severe Acute Respiratory Syndrome

    PubMed Central

    Pfeiffer, Dirk; Oshitani, Hitoshi

    2013-01-01

    It is 10 years since severe acute respiratory syndrome (SARS) emerged, and East and Southeast Asia retain a reputation as a hot spot of emerging infectious diseases. The region is certainly a hot spot of socioeconomic and environmental change, and although some changes (e.g., urbanization and agricultural intensification) may reduce the probability of emerging infectious diseases, the effect of any individual emergence event may be increased by the greater concentration and connectivity of livestock, persons, and products. The region is now better able to detect and respond to emerging infectious diseases than it was a decade ago, but the tools and methods to produce sufficiently refined assessments of the risks of disease emergence are still lacking. Given the continued scale and pace of change in East and Southeast Asia, it is vital that capabilities for predicting, identifying, and controlling biologic threats do not stagnate as the memory of SARS fades. PMID:23738977

  12. Prospects for emerging infections in East and southeast Asia 10 years after severe acute respiratory syndrome.

    PubMed

    Horby, Peter W; Pfeiffer, Dirk; Oshitani, Hitoshi

    2013-06-01

    It is 10 years since severe acute respiratory syndrome (SARS) emerged, and East and Southeast Asia retain a reputation as a hot spot of emerging infectious diseases. The region is certainly a hot spot of socioeconomic and environmental change, and although some changes (e.g., urbanization and agricultural intensification) may reduce the probability of emerging infectious diseases, the effect of any individual emergence event may be increased by the greater concentration and connectivity of livestock, persons, and products. The region is now better able to detect and respond to emerging infectious diseases than it was a decade ago, but the tools and methods to produce sufficiently refined assessments of the risks of disease emergence are still lacking. Given the continued scale and pace of change in East and Southeast Asia, it is vital that capabilities for predicting, identifying, and controlling biologic threats do not stagnate as the memory of SARS fades.

  13. Predictors Associated with Changes of Weight and Total Cholesterol among two Occupational Cohorts over 10 Years

    PubMed Central

    Stanford, Joseph B.; Murtaugh, Maureen A.; Greenwood, Jessica L.J.; Gren, Lisa H.; Hegmann, Kurt T.; Thiese, Matthew S.

    2015-01-01

    Objective To ascertain worker health characteristics and psychosocial factors associated with changes in body weight and total cholesterol (TC) among two production operation populations. Methods We performed descriptive and predictive analysis of questionnaire data and biomedical measurements from two prospective cohort studies. Our key outcomes were changes in weight, and TC over 5–10 years between baseline and exit assessments. Results 146 subjects were analyzed. Increases in weight were associated with belief in being overweight and baseline overweight and obesity. Increases in TC levels were associated with female gender, belief that TC levels were “not good,” and feeling depressed. Conclusion Most of the reported associations with increases in weight and TC levels are amenable to interventions and may be a target for workplace intervention programs. PMID:26147542

  14. Federal Transit Administration's noise and vibration Guidance Manual: Updates after 10 years of experience

    NASA Astrophysics Data System (ADS)

    Hanson, Carl E.

    2005-09-01

    In April 1995, the Federal Transit Administration of the U.S. Department of Transportation issued its guidance manual, ``Transit Noise and Vibration Impact Assessment.'' The manual was written to provide direction for the preparation of noise and vibration sections of environmental documents for public transportation projects in the interest of promoting quality and uniformity in assessments. In the 10 years since its release, the guidance manual has been used as the basis of noise and vibration assessments in over 80 environmental documents and has been used worldwide as a standard method for performing transit noise analyses. An updated version has recently been prepared that takes account of improvements in tools, changes in the environmental assessment procedures, modifications of impact criteria, and experience with mitigation measures. These factors, and other background information, will be discussed to provide insight regarding the revisions in the new edition.

  15. Spectral Methods for Detecting Periodicity in Library Circulation Data: A Case Study.

    ERIC Educational Resources Information Center

    Decroos, Francis; And Others

    1997-01-01

    Describes an investigation that was conducted to show the feasibility of spectral methods in information science, particularly for analyzing academic library circulation data. Signal analysis methods were used to detect periodicity, and spectral methods show promise for analyzing time series and other signals in information science. (Author/LRW)

  16. A 10-Year Retrospective Review of a Nonrandomized Cohort of 458 Patients Undergoing Radical Radiotherapy or Cystectomy in Yorkshire, UK

    SciTech Connect

    Munro, Nicholas P.; Sundaram, Subramnian K.; Weston, Philip; Fairley, Lesley; Harrison, Simon C.W.; Forman, David; Chahal, Rohit

    2010-05-01

    Purpose: We have previously reported on the mortality, morbidity, and 5-year survival of 458 patients who underwent radical radiotherapy or surgery for invasive bladder cancer in Yorkshire from 1993 to 1996. We aim to present the 10-year outcomes of these patients and to reassess factors predicting survival. Methods and Materials: The Northern and Yorkshire Cancer Registry identified 458 patients whose cases were subjected to Kaplan-Meier all-cause survival analyses, and a retrospective casenote analysis was undertaken on 398 (87%) for univariate and multivariate Cox proportional hazards modeling. Additional proportional hazards regression modeling was used to assess the statistical significance of variables on overall survival. Results: The ratio of radiotherapy to cystectomy was 3:1. There was no significant difference in overall 10-year survival between those who underwent radiotherapy (22%) and radical cystectomy (24%). Univariate analyses suggested that female sex, performance status, hydronephrosis and clinical T stage, were associated with an inferior outcome at 10 years. Patient age, tumor grade, treatment delay, and caseload factors were not significant. Multivariate analysis models were created for 0-2 and 2-10 years after treatment. There were no significant differences in treatment for 0-2 years; however, after 2 years follow-up there was some evidence of increased survival for patients receiving surgery compared with radiotherapy (hazard ratio 0.66, 95% confidence interval: 0.44-1.01, p = 0.06). Conclusions: a 10-year minimum follow-up has rarely been reported after radical treatment for invasive bladder cancer. At 10 years, there was no statistical difference in all-cause survival between surgery and radiotherapy treatment modalities.

  17. Homogenization of Periodic Masonry Using Self-Consistent Scheme and Finite Element Method

    NASA Astrophysics Data System (ADS)

    Kumar, Nitin; Lambadi, Harish; Pandey, Manoj; Rajagopal, Amirtham

    2016-01-01

    Masonry is a heterogeneous anisotropic continuum, made up of the brick and mortar arranged in a periodic manner. Obtaining the effective elastic stiffness of the masonry structures has been a challenging task. In this study, the homogenization theory for periodic media is implemented in a very generic manner to derive the anisotropic global behavior of the masonry, through rigorous application of the homogenization theory in one step and through a full three-dimensional behavior. We have considered the periodic Eshelby self-consistent method and the finite element method. Two representative unit cells that represent the microstructure of the masonry wall exactly are considered for calibration and numerical application of the theory.

  18. The direct approach to gravitation and electrostatics method for periodic systems.

    PubMed

    Losilla, S A; Sundholm, D; Jusélius, J

    2010-01-14

    The direct approach to gravitation and electrostatics (DAGE) algorithm is an accurate, efficient, and flexible method for calculating electrostatic potentials. In this paper, we show that the algorithm can be easily extended to consider systems with many different kinds of periodicities, such as crystal lattices, surfaces, or wires. The accuracy and performance are nearly the same for periodic and aperiodic systems. The electrostatic potential for semiperiodic systems, namely defects in crystal lattices, can be obtained by combining periodic and aperiodic calculations. The method has been applied to an ionic model system mimicking NaCl, and to a corresponding covalent model system.

  19. Self-Esteem during University Studies Predicts Career Characteristics 10 Years Later

    ERIC Educational Resources Information Center

    Salmela-Aro, Katariina; Nurmi, Jari-Erik

    2007-01-01

    To examine how self-esteem measured during university studies would impact on the characteristics of the work career 10 years later, 297 university students completed the Rosenberg's self-esteem inventory four times while at university and various career-related questionnaires 10 years later. Latent Growth Curve Modeling showed that a high overall…

  20. Effect of Ocular Alignment on Emmetropization in Children <10 years with Amblyopia

    PubMed Central

    Kulp, Marjean T.; Foster, Nicole C.; Holmes, Jonathan M.; Kraker, Raymond T.; Melia, B. Michele; Repka, Michael X.; Tien, D. Robbins

    2012-01-01

    Purpose To determine whether change in refractive error is associated with ocular alignment in 105 children 3 to <7 years of age who previously participated in a randomized trial comparing atropine and patching for moderate amblyopia. Design Prospective cohort study Methods One hundred five children 3 to <7 years of age previously participated in a randomized trial comparing atropine with patching for moderate amblyopia. Cycloplegic refraction was measured at baseline and 10 years of age. Ocular alignment at baseline was categorized as orthotropic, microtropic (1–8Δ horizontal tropia), or heterotropic (>8Δ horizontal tropia). Multivariate regression models evaluated whether change in spherical equivalent refractive error was associated with alignment category, after adjusting for age, baseline spherical equivalent refractive error, and type of amblyopia treatment. Results Between enrollment and the age 10-year exam there was a decrease in spherical equivalent refractive error from hyperopia to less hyperopia (amblyopic eye: − 0.65D, 95%CI −0.85, −0.46; fellow eye: −0.39D, 95%CI −0.58, −0.20). A greater decrease in amblyopic eye refractive error was associated with better ocular alignment category (p=0.004), with the greatest decrease occurring in orthotropic patients. There was no relationship between ocular alignment category and change in fellow-eye refractive error. Conclusions Among children treated for anisometropic, strabismic, or combined mechanism amblyopia, there is a decrease in amblyopic eye spherical equivalent refractive error to less hyperopia after controlling for baseline refractive error. This negative shift toward emmetropia is associated with ocular alignment, which supports the suggestion that better motor and sensory fusion promote emmetropization. PMID:22633344

  1. Treatment of Bilateral Refractive Amblyopia in Children 3 to <10 Years Old

    PubMed Central

    Wallace, David; Chandler, Danielle L.; Beck, Roy W.; Arnold, Robert W.; Bacal, Darron A.; Birch, Eileen E.; Felius, Joost; Frazier, Marcela; Holmes, Jonathan M.; Hoover, Darren; Klimek, Deborah A.; Lorenzana, Ingryd; Quinn, Graham E.; Repka, Michael X.; Suh, Donny W.; Tamkins, Susanna

    2007-01-01

    Purpose To determine the amount and time course of binocular visual acuity improvement during treatment of bilateral refractive amblyopia in children age 3 to <10 years old Design Prospective, multicenter noncomparative intervention Methods 113 children (mean age = 5.1 years) with previously untreated bilateral refractive amblyopia were enrolled at 27 community- and university-based sites and were provided optimal spectacle correction. Bilateral refractive amblyopia was defined as 20/40 to 20/400 best-corrected binocular acuity in the presence of ≥ 4.00 D hypermetropia by spherical equivalent and/or ≥ 2.00 D astigmatism in each eye. Best-corrected binocular and monocular visual acuities were measured at baseline and at 5, 13, 26 and 52 weeks. The primary study outcome was binocular acuity at one year. Results Mean binocular visual acuity improved from 0.50 logMAR (20/63) at baseline to 0.11 logMAR (20/25) at one year (mean improvement 3.9 lines, 95% confidence interval [CI] = 3.5 to 4.2). Mean improvement at one year for the 84 children with baseline binocular acuity of 20/40 to 20/80 was 3.4 lines (95% CI = 3.2 to 3.7) and for the 16 children with baseline binocular acuity of 20/100 to 20/320 was 6.3 lines (95% CI = 5.1 to 7.5). The cumulative probability of binocular acuity of 20/25 or better was 21% at 5 weeks, 46% at 13 weeks, 59% at 26 weeks, and 74% at 52 weeks. Conclusions Treatment of bilateral refractive amblyopia with spectacle correction improves binocular visual acuity in children age 3 to <10 years old, with most improving to 20/25 or better within one year. PMID:17707330

  2. Type 2 Diabetes and 10-Year Risk of Dementia and Cognitive Impairment Among Older Mexican Americans

    PubMed Central

    Mayeda, Elizabeth R.; Haan, Mary N.; Kanaya, Alka M.; Yaffe, Kristine; Neuhaus, John

    2013-01-01

    OBJECTIVE Type 2 diabetes has been linked with increased risk of dementia and cognitive impairment among older adults and with premature mortality in young and middle-aged adults. No studies have evaluated the association between diabetes and dementia among Mexican Americans, a population with a high burden of diabetes. We evaluated the association of diabetes with incidence of dementia and cognitive impairment without dementia (CIND) among older Mexican Americans while accounting for competing risk from death. RESEARCH DESIGN AND METHODS This study included 1,617 participants 60–98 years of age from the Sacramento Area Latino Study on Aging followed up to 10 years from 1998. We evaluated the association between diabetes and dementia/CIND with competing risk regression models. RESULTS Participants free of dementia/CIND at baseline (n = 1,617) were followed annually up to 10 years. There were 677 (41.9%) participants with diabetes, 159 (9.8%) incident dementia/CIND cases, and 361 (22.3%) deaths. Treated and untreated diabetes (hazard ratio 2.12 [95% CI 1.65–2.73] and 2.15 [1.58–2.95]) and dementia/CIND (2.48 [1.75–3.51]) were associated with an increased risk of death. In models adjusted for competing risk of death, those with treated and untreated diabetes had an increased risk of dementia/CIND (2.05 [1.41–2.97] and 1.55 [0.93–2.58]) compared with those without diabetes. CONCLUSIONS These findings provide evidence that the association between type 2 diabetes and dementia/CIND among Mexican Americans remains strong after accounting for competing risk of mortality. Treatments that modify risk of death among those with diabetes may change future dementia risk. PMID:23514732

  3. Financial problems and health complaints among farm couples: results of a 10-year follow-up study.

    PubMed

    Gorgievski-Duijvesteijn, M J; Giesen, C W; Bakker, A B

    2000-07-01

    Over a 10-year period, this survey study of 91 Dutch dairy farm couples investigated both causal and reversed causal relationships between couples' financial problems and husbands' and wives' mental and physical health complaints, as well as crossover effects of mental and physical health complaints between spouses. These relationships were tested simultaneously using structural equation modeling analyses. Results showed that financial problems were not predictive of health complaints for either spouse but that husbands' health complaints did predict both couples' financial problems and wives' health complaints 10 years later. These findings emphasize the importance of mental and physical health as resources for both the business and the family. For wives, these effects were not found, which may reflect the different positions of husbands and wives at the farm and, hence, the different ways they allocate their resources.

  4. Heterotopic ossification: review of histologic findings and tissue distribution in a 10-year experience.

    PubMed

    Liu, Katharine; Tripp, Sheryl; Layfield, Lester J

    2007-01-01

    Heterotopic ossification (HO) within tissues involved by a pathologic process is a well-recognized phenomenon. It is most frequently observed in atherosclerotic plaques, in soft tissue around joints, and in the central nervous system. Less frequently, carcinomas and some benign neoplasms will undergo heterotopic ossification. We performed a retrospective review of our experience with HO over a 10-year period to determine the frequency and tissue site distribution of heterotopic ossification. A computerized review of surgical pathology records of approximately 126,000 reports revealed 85 cases in which heterotopic ossification, ectopic bone or metaplastic bone was specifically mentioned in the surgical pathology diagnosis. Twenty-two cases were neoplasms of non-osseous tissues, and 63 cases were non-neoplastic lesions. Immunohistochemical staining for bone morphogenic proteins (BMP) 1, 4, and 6 was performed. Fourteen cases showed staining for BMP-1, 22 cases showed staining for BMP-4, and five cases showed weak staining for BMP-6. HO is a relatively infrequent finding and is more commonly seen in degenerative and reparative conditions than in neoplasms. PMID:17728073

  5. Impacts of Natural Hazards on Primary Health Care Facilities of Iran: A 10-Year Retrospective Survey

    PubMed Central

    Ardalan, Ali; Mowafi, Hani; Yousefi, Homa

    2013-01-01

    Public health facilities in Iran are exposed to a wide range of natural hazards. This article presents the first survey of the impacts of such natural hazards on primary health care (PHC) centers in Iran from 2001 to 2011. A retrospective survey was conducted in 25 out of 30 provinces of Iran. Archival reports at provincial public health departments were cross-referenced with key informant interviews. During a 10-year period, 119 natural hazard events were recorded that led to physical damage and/or functional failure in 1,401 health centers, 127 deaths and injury or illness in 644 health staff. Earthquakes accounted for the most physical damage and all health-worker deaths. However, there was an increasing trend of impacts due to hydro-meteorological hazards. Iran’s health system needs to establish a registry to track the impact of natural hazards on health facilities, conduct regular hazard and vulnerability assessments and increase mitigation and preparedness measures. Keywords: Disaster, primary health care, facility, Iran, natural hazard Corresponding author: Ali Ardalan MD, PhD. Iran’s National Institute of Health Research, Tehran University of Medical Sciences. Harvard Humanitarian Initiative. Email: aardalan@tums.ac.ir PMID:23863871

  6. Global Tpw and Uth Trends Inferred from 10 Years of Hiirs and MODIS Data

    NASA Astrophysics Data System (ADS)

    Borbas, E. E.; Menzel, P.; Frey, R.; Heidinger, A. K.; Bearson, N.

    2014-12-01

    The HIRS and MODIS (MOD07) TPW and UTH algorithm retrieves total column precipitable water vapor and integrated high (UTH), mid, and low layer tropospheric humidity. It is a statistical regression (Seemann et al 2003 and 2008) developed from an atmospheric profile data base (SeeBor, Borbas et al, 2005) that consists of geographically and seasonally distributed radiosonde, ozonesonde, and ECMWF ReAnalysis data. TPW and UTH are determined for clear sky radiances measured by HIRS (at 20km and later 10km resolution) and MODIS (5km resolution) over land and ocean both day and night. The Space Time Gridding (STG) framework is used to calculate daily and monthly composites of the moisture properties. It has two components. (1) Space gridding where geophysical properties are first filtered based on a set of criteria (e.g. time of day, etc.) and then aggregated into equal-angle grid cells. (2) Time gridding where daily statistics are computed from the aggregate of pixels in each grid cell. Longer-term, such as monthly, statistics are derived from the daily gridded statistics. The HIRS and MODIS TPW and UTH products are binned into a global map of 0.5 degree lat-lon boxes daily, compiled into monthly amounts, and inspected for trends over a 10-year time period (2000-2009). The HIRS and MODIS TPW data is also compared to the NASA NVAP dataset.

  7. The incidence of secondary tumors of the heart and pericardium: a 10-year study.

    PubMed

    Mukai, K; Shinkai, T; Tominaga, K; Shimosato, Y

    1988-09-01

    Secondary tumors of the heart and pericardium are much more common than primary tumors. During a 10-year period (1976-1985), only one instance of a primary tumor (malignant mesothelioma) was identified among 2,649 autopsies of malignant tumors at the National Cancer Center Hospital. In contrast, there were 407 cases in which heart and/or pericardium were secondarily involved with a malignant tumor from other organs. In 78 cases, the secondary tumors were present only in the pericardium, while in 329 cases, the tumors involved the heart itself with or without pericardial involvement. Among the primary tumors, three-quarters were carcinomas of various organs. In addition there were 53 hematologic malignancies, 19 melanomas and 17 sarcomas. In 31 cases, cardiac failure was the direct cause of death. The secondary tumors of the heart were often overlooked clinically because the cardiac dysfunction appeared to be part of the deteriorating general condition. Electrocardiography and echocardiography were often helpful in suggesting the presence of cardiac metastases. Appropriate diagnostic procedures and therapeutic intervention should be considered for the care of patients with advanced malignancy and sudden onset of cardiac failure.

  8. Early treatment of Class III malocclusion: 10-year clinical follow-up

    PubMed Central

    de ALMEIDA, Marcio Rodrigues; de ALMEIDA, Renato Rodrigues; OLTRAMARI-NAVARRO, Paula Vanessa Pedron; CONTI, Ana Cláudia de Castro Ferreira; NAVARRO, Ricardo de Lima; CAMACHO, José Gustavo Dala Déa

    2011-01-01

    Angle Class III malocclusion has been a challenge for researchers concerning diagnosis, prognosis and treatment. It has a prevalence of 5% in the Brazilian population, and may have a genetic or environmental etiology. This malocclusion can be classified as dentoalveolar, skeletal or functional, which will determine the prognosis. Considering these topics, the aim of this study was to describe and discuss a clinical case with functional Class III malocclusion treated by a two-stage approach (interceptive and corrective), with a long-term follow-up. In this case, the patient was treated with a chincup and an Eschler arch, used simultaneously during 14 months, followed by corrective orthodontics. It should be noticed that, in this case, initial diagnosis at the centric relation allowed visualizing the anterior teeth in an edge-to-edge relationship, thereby favoring the prognosis. After completion of the treatment, the patient was followed for a 10-year period, and stability was observed. The clinical treatment results showed that it is possible to achieve favorable outcomes with early management in functional Class III malocclusion patients. PMID:21952927

  9. Atmospheric emissions and trends of nitrous oxide deduced from 10 years of ALE-GAGE data

    NASA Technical Reports Server (NTRS)

    Prinn, R.; Cunnold, D.; Alyea, F.; Rasmussen, R.; Simmonds, P.

    1990-01-01

    Long-term measurements of nitrous oxide (N2O) obtained during the Atmospheric Lifetime Experiment (ALE) and the Global Atmospheric Gases Experiment (GAGE) for a period from 1978 to 1988 are presented and interpreted. It is observed that the average concentration in the Northern Hemisphere is 0.75 +/- 0.16 ppbv higher than in the Southern Hemisphere and that the global average linear trend in N2O lies in the range from 0.25 to 0.31 percent/year. The measured trends and latitudinal distributions are shown to be consistent with the hypothesis that stratospheric photodissociation is the major atmospheric sink for N2O, while the cause of the N2O trend is suggested to be a combination of a growing tropical source and a growing Northern mid-latitude source. A 10-year average global N2O emission rate of (20.5 +/- 2.4) x 10 to the 12th g N2O/year is deduced from the ALE/GAGE data.

  10. Ecosystem Service Restoration after 10 Years of Rewetting Peatlands in NE Germany

    NASA Astrophysics Data System (ADS)

    Zerbe, Stefan; Steffenhagen, Peggy; Parakenings, Karsten; Timmermann, Tiemo; Frick, Annett; Gelbrecht, Jörg; Zak, Dominik

    2013-06-01

    The restoration of ecosystem services, i.e., production, regulation, and information, is a global challenge, which the federal state of Mecklenburg-Vorpommern in NE Germany addressed in 2000 by rewetting over 20,000 ha of degraded peatlands within the Mire Restoration Program. We evaluated ecosystem services in 23 rewetted sites by assessing the following mire parameters within a ten year period: (a) dominant vegetation at the ecosystem level, (b) peat formation potential at the landscape level, and (c) aboveground biomass and nutrient levels. Seven to 10 years after rewetting, the wetlands formed a mosaic of vegetation types with the highest potential for peat formation and several dominant, peat-forming species accumulated high levels of aboveground biomass and nutrients (C, N, P). Common reed ( Phragmites australis) accumulated the most biomass (up to 24 t dry matter/ha), and N+P during the growing season. A future management option is to annually harvest aquatic and wetland plants to reduce nutrient levels in restored mire ecosystems.

  11. Argon laser panretinal photocoagulation in ischemic central retinal vein occlusion. A 10-year prospective study.

    PubMed

    Hayreh, S S; Klugman, M R; Podhajsky, P; Servais, G E; Perkins, E S

    1990-01-01

    We conducted a prospective, planned study of argon laser panretinal photocoagulation (PRP) in ischemic central retinal vein occlusion (CRVO) over a 10-year period in 123 eyes. On comparing the lasered eyes versus the nonlasered eyes, there was no statistically significant difference between the two groups in the incidence of development of angle neovascularization (NV), neovascular glaucoma (NVG), retinal and/or optic disc NV, or vitreous hemorrhage, or in visual acuity. Our study, however, did show a statistically significant (P = 0.04) difference in the incidence of iris NV between the two groups, with iris NV less prevalent in the laser group than in the nonlaser group, but only when the PRP was performed within 90 days after the onset of CRVO. The other parameter which showed a statistically significant difference between the two groups was the peripheral visual fields-the laser group suffered a significantly (P less than or equal to 0.03) greater loss than the non-laser group. We discuss the implications of these findings in light of the natural history of ischemic CRVO and of ocular NV. Since the original rationale for advocating PRP in ischemic CRVO was the proven beneficial effect of PRP on ocular NV in proliferative diabetic retinopathy, we also discuss the disparities in the disease process between ischemic CRVO and proliferative diabetic retinopathy and in their responses to PRP. PMID:1698170

  12. Ecosystem service restoration after 10 years of rewetting peatlands in NE Germany.

    PubMed

    Zerbe, Stefan; Steffenhagen, Peggy; Parakenings, Karsten; Timmermann, Tiemo; Frick, Annett; Gelbrecht, Jörg; Zak, Dominik

    2013-06-01

    The restoration of ecosystem services, i.e., production, regulation, and information, is a global challenge, which the federal state of Mecklenburg-Vorpommern in NE Germany addressed in 2000 by rewetting over 20,000 ha of degraded peatlands within the Mire Restoration Program. We evaluated ecosystem services in 23 rewetted sites by assessing the following mire parameters within a ten year period: (a) dominant vegetation at the ecosystem level, (b) peat formation potential at the landscape level, and (c) aboveground biomass and nutrient levels. Seven to 10 years after rewetting, the wetlands formed a mosaic of vegetation types with the highest potential for peat formation and several dominant, peat-forming species accumulated high levels of aboveground biomass and nutrients (C, N, P). Common reed (Phragmites australis) accumulated the most biomass (up to 24 t dry matter/ha), and N+P during the growing season. A future management option is to annually harvest aquatic and wetland plants to reduce nutrient levels in restored mire ecosystems. PMID:23636204

  13. Steady-periodic method for modeling mode instability in fiber amplifiers.

    PubMed

    Smith, Arlee V; Smith, Jesse J

    2013-02-11

    We present a detailed description of the methods used in our model of mode instability in high-power, rare earth-doped, large-mode-area fiber amplifiers. Our model assumes steady-periodic behavior, so it is appropriate to operation after turn on transients have dissipated. It can be adapted to transient cases as well. We describe our algorithm, which includes propagation of the signal field by fast-Fourier transforms, steady-state solutions of the laser gain equations, and two methods of solving the time-dependent heat equation: alternating-direction-implicit integration, and the Green's function method for steady-periodic heating.

  14. Very Weak Signals (VWS) detected by stacking method according to different astronomical periodicities (HiCum)

    NASA Astrophysics Data System (ADS)

    van Ruymbeke, M.; Zhu, P.; Cadicheanu, N.; Naslin, S.

    2007-11-01

    A stacking method to detect very weak signals is introduced in this paper. This method is to stack observed data in different well known periodicities according to the astronomical clock since majority geophysical observations are time based. We validated this method by applying it in four different cases. Interactions behind the observed parameters become obviously after it is stacked in two diurnal and semidiurnal tidal periodical waves. Amplitude and phase variations will be also measurable when a sliding windows stacking is used. This could be an important reference to find precursors before some earthquakes and volcanic events, corresponding to attenuations of medium patterns.

  15. A New Method for Studying the Periodic System Based on a Kohonen Neural Network

    ERIC Educational Resources Information Center

    Chen, David Zhekai

    2010-01-01

    A new method for studying the periodic system is described based on the combination of a Kohonen neural network and a set of chemical and physical properties. The classification results are directly shown in a two-dimensional map and easy to interpret. This is one of the major advantages of this approach over other methods reported in the…

  16. A novel sensitivity-based method for damage detection of structures under unknown periodic excitations

    NASA Astrophysics Data System (ADS)

    Naseralavi, S. S.; Salajegheh, E.; Fadaee, M. J.; Salajegheh, J.

    2014-06-01

    This paper presents a technique for damage detection in structures under unknown periodic excitations using the transient displacement response. The method is capable of identifying the damage parameters without finding the input excitations. We first define the concept of displacement space as a linear space in which each point represents displacements of structure under an excitation and initial condition. Roughly speaking, the method is based on the fact that structural displacements under free and forced vibrations are associated with two parallel subspaces in the displacement space. Considering this novel geometrical viewpoint, an equation called kernel parallelization equation (KPE) is derived for damage detection under unknown periodic excitations and a sensitivity-based algorithm for solving KPE is proposed accordingly. The method is evaluated via three case studies under periodic excitations, which confirm the efficiency of the proposed method.

  17. Work stress, sleep deficiency and predicted 10-year cardiometabolic risk in a female patient care worker population

    PubMed Central

    Jacobsen, Henrik Børsting; Reme, Silje Endresen; Sembajwe, Grace; Hopcia, Karen; Stiles, Tore C.; Sorensen, Glorian; Porter, James H.; Marino, Miguel; Buxton, Orfeu M.

    2014-01-01

    Objectives The aim of this study was to investigate the longitudinal effect of work-related stress, sleep deficiency and physical activity on 10-year cardiometabolic risk among an all-female worker population. Methods Data on patient care workers (n=99) was collected two years apart. Baseline measures included: job stress, physical activity, night work and sleep deficiency. Biomarkers and objective measurements were used to estimate 10-year cardiometabolic risk at follow-up. Significant associations (P<0.05) from baseline analyses were used to build a multivariable linear regression model. Results The participants were mostly white nurses with a mean age of 41 years. Adjusted linear regression showed that having sleep maintenance problems, a different occupation than nurse, and/or not exercising at recommended levels at baseline increased the 10-year cardiometabolic risk at follow-up. Conclusions In female workers prone to work-related stress and sleep deficiency, maintaining sleep and exercise patterns had a strong impact on modifiable 10-year cardiometabolic risk. PMID:24809311

  18. An Analysis of Periodic Components in BL Lac Object S5 0716 +714 with MUSIC Method

    NASA Astrophysics Data System (ADS)

    Tang, J.

    2012-01-01

    Multiple signal classification (MUSIC) algorithms are introduced to the estimation of the period of variation of BL Lac objects.The principle of MUSIC spectral analysis method and theoretical analysis of the resolution of frequency spectrum using analog signals are included. From a lot of literatures, we have collected a lot of effective observation data of BL Lac object S5 0716 + 714 in V, R, I bands from 1994 to 2008. The light variation periods of S5 0716 +714 are obtained by means of the MUSIC spectral analysis method and periodogram spectral analysis method. There exist two major periods: (3.33±0.08) years and (1.24±0.01) years for all bands. The estimation of the period of variation of the algorithm based on the MUSIC spectral analysis method is compared with that of the algorithm based on the periodogram spectral analysis method. It is a super-resolution algorithm with small data length, and could be used to detect the period of variation of weak signals.

  19. The Remains of the Dam: What Have We Learned From 10 Years of Dam Removals?

    NASA Astrophysics Data System (ADS)

    Grant, G. E.; O'Connor, J. E.; Major, J. J.

    2012-12-01

    Over the past 10 years in the U.S., dam removal has evolved from an occasionally implemented, rarely studied, and poorly understood intervention to improve rivers, to a much more frequently accomplished and better studied and understood approach to river restoration. Over that same time period, the numbers and sizes of dams and volumes of sediment released have dramatically increased. By some estimates close to 1000 dams have been removed over the last 100 years, with most of those occurring within the last 10. While most of these are small (less than 15 m high) dams, removals of dams up to 70 m high are presently underway. Releases of sediment associated with these removals over the past 10 years have also increased by close to four orders of magnitude; for example removal of the Elwha River dams in Washington is estimated to release almost 107 m3 of sediment into the lower Elwha River. Given a decade's worth of dam removals and, in some cases, well-orchestrated case studies of the effects of removal on the geomorphology and (to a lesser extent) ecology of rivers, what have we learned? More specifically, where do we now stand with respect to being able to predict the consequences of future dam removals? Drawing on both field examples and numerical models of dam removals in the western U.S., several key lessons stand out. Although every dam removal and river are different, removals initiate very rapid upstream river response and reservoir erosion and evacuation of sediment by various mechanisms that are strongly controlled by grain size of the deposit, volumes of residual sediment relative to total reservoir volume, and style of dam removal (instantaneous versus staged). Erosion of sediment accumulations in fully and partially filled (by sediment) reservoirs proceeds by different trajectories and rates, with full reservoirs releasing sediment primarily by upstream knickpoint retreat while erosion and sediment release in partially-filled reservoirs proceeds by

  20. Climatological Analysis of the Exclusive Economic Zone of Mexico Based on 10 Years of Satellite Imagery

    NASA Astrophysics Data System (ADS)

    Gonzalez Rodriguez, E.; Trasviña-Castro, A.; Aguirre Bahena, F.

    2013-05-01

    low (<25 mg m-3) and are not found associated to low temperatures and/or low depths of the euphotic zone. The oceanic region shows maximum values for both sea surface temperatures and depth of the euphotic zone as is to be expected in oligotrophic regions of the sea. Anomalies for all three variables will also shown to discuss the interannual variability of this 10-years period of study.

  1. Long period perturbations of earth satellite orbits. [Von Zeipel method and zonal harmonics

    NASA Technical Reports Server (NTRS)

    Wang, K. C.

    1979-01-01

    All the equations involved in extending the PS phi solution to include the long periodic and second order secular effects of the zonal harmonics are presented. Topics covered include DSphi elements and relations for their conconical transformation into the PS phi elements; the solution algorithm based on the Von Zeipel method; and the elimination of long periodic terms and analytical integration of primed variables. The equations were entered into the ASOP program, checked out, and verified. Comparisons with numerical integrations show the long period theory to be accurate within several meters after 800 revolutions.

  2. Method for detection and correction of errors in speech pitch period estimates

    NASA Technical Reports Server (NTRS)

    Bhaskar, Udaya (Inventor)

    1989-01-01

    A method of detecting and correcting received values of a pitch period estimate of a speech signal for use in a speech coder or the like. An average is calculated of the nonzero values of received pitch period estimate since the previous reset. If a current pitch period estimate is within a range of 0.75 to 1.25 times the average, it is assumed correct, while if not, a correction process is carried out. If correction is required successively for more than a preset number of times, which will most likely occur when the speaker changes, the average is discarded and a new average calculated.

  3. Method for minimization of solution costs for transient dynamic analysis of nonlinear periodic structures

    SciTech Connect

    Van Kirk, J.S.; Bogard, W.T.; Wood, L.R.

    1982-01-01

    Techniques are described for the transient dynamic analysis of nonlinear periodic structures subjected to time history excitations. These techniques consider the special characteristics of periodic structures in conjunction with the psuedo-force approach in numerical integration to reduce computerized solution costs. A special purpose computer code, based on these techniques, is applied to a specific nonlinear periodic structure: the response of a pressurized water reactor core to a postulated main coolant pipe rupture. Comparisons with a general purpose finite element code, using consistent integration methods, demonstrate the savings in solution cost.

  4. PLANT POISONING IN THAILAND: A 10-YEAR ANALYSIS FROM RAMATHIBODI POISON CENTER.

    PubMed

    Sriapha, Charuwan; Tongpoo, Achara; Wongvisavakorn, Sunun; Rittilert, Panee; Trakulsrichai, Satariya; Srisuma, Sahaphume; Wananukul, Winai

    2015-11-01

    Plant poisoning is not uncommon in Thailand. The objective of this study was to determine the incidence, type, clinical manifestations, severity and outcomes of plant poisoned patients in Thailand over a 10-year period. We retrospectively reviewed data from the Ramathibodi Poison Center Toxic Exposure Surveillance System for 2001-2010. A total of 2,901 poisonous plant exposure cases were identified, comprising 3.1% of the 92,392 poison cases recorded during the study period. This was the fifth most common type of poisoning recorded. Children aged < 13 years comprised the largest percent (69.8%) of the cases. The major type of exposure was unintentional ingestion. Ninety-nine types of poisonous plants were recorded as the causative agents among 99.1%of the cases. Gastrointestinal symptoms were reported in 72.0% of cases with Jatropha curcas (physic nut) comprising 54.1% of these. Most patients had only minor signs and symptoms. The mortality rate among the total plant poisoning cases was 0.9%, with 26 deaths. Thirteen deaths occurred in children aged < 13 years. The greatest number of fatalities were due to ingestion of Manihot esculenta (cassava), primarily due to multi-system organ failure. Children aged < 13 years are at the greatest risk for plant poisoning in Thailand; mostly unintentional. Most cases were minor and the mortality rate was low. Jatropha curcas was the most common cause of poisoning and Manihot esculenta was the most common cause of death. Public education is important to minimize these poisonings.

  5. PLANT POISONING IN THAILAND: A 10-YEAR ANALYSIS FROM RAMATHIBODI POISON CENTER.

    PubMed

    Sriapha, Charuwan; Tongpoo, Achara; Wongvisavakorn, Sunun; Rittilert, Panee; Trakulsrichai, Satariya; Srisuma, Sahaphume; Wananukul, Winai

    2015-11-01

    Plant poisoning is not uncommon in Thailand. The objective of this study was to determine the incidence, type, clinical manifestations, severity and outcomes of plant poisoned patients in Thailand over a 10-year period. We retrospectively reviewed data from the Ramathibodi Poison Center Toxic Exposure Surveillance System for 2001-2010. A total of 2,901 poisonous plant exposure cases were identified, comprising 3.1% of the 92,392 poison cases recorded during the study period. This was the fifth most common type of poisoning recorded. Children aged < 13 years comprised the largest percent (69.8%) of the cases. The major type of exposure was unintentional ingestion. Ninety-nine types of poisonous plants were recorded as the causative agents among 99.1%of the cases. Gastrointestinal symptoms were reported in 72.0% of cases with Jatropha curcas (physic nut) comprising 54.1% of these. Most patients had only minor signs and symptoms. The mortality rate among the total plant poisoning cases was 0.9%, with 26 deaths. Thirteen deaths occurred in children aged < 13 years. The greatest number of fatalities were due to ingestion of Manihot esculenta (cassava), primarily due to multi-system organ failure. Children aged < 13 years are at the greatest risk for plant poisoning in Thailand; mostly unintentional. Most cases were minor and the mortality rate was low. Jatropha curcas was the most common cause of poisoning and Manihot esculenta was the most common cause of death. Public education is important to minimize these poisonings. PMID:26867365

  6. Course of Depression in a 10-year Prospective Study: Evidence for Qualitatively Distinct Subgroups

    PubMed Central

    Klein, Daniel N.; Kotov, Roman

    2016-01-01

    The course of depressive disorders can vary considerable, with some individuals exhibiting a chronic course and poor outcomes, while others have a more episodic course and better outcomes. However it is unclear whether degree of chronicity is continuous or reflects qualitatively distinct subgroups. Using data from a 5-wave, 10-year, naturalistic study of 127 depressed outpatients, we examined whether depression chronicity lies on a continuum or manifests natural boundaries. Spline regression was used to test 7 continuous and discontinuous models of the relationship between depression during the first follow-up interval and multiple outcomes at subsequent follow-ups. In order to further validate the findings, we also created empirically-derived subgroups based on the results of the spline regression analyses and compared them on baseline clinical characteristics and long-term outcomes. There was a clear and consistent discontinuity indicating that for higher levels of chronicity during the first 30 month period, depression was linearly related to outcome; in contrast, for lower levels of chronicity, depression in the initial interval was unrelated to subsequent outcomes. The findings were strikingly consistent across the 4 follow-up evaluations using multiple outcomes and goodness-of-fit indices. In addition, the chronic group--as defined by the first follow-up period--exhibited more baseline chronic depression, anxiety and personality disorders, family history of dysthymia, and childhood adversity, and was more likely to attempt suicide and be hospitalized during follow-up, than the non-chronic group. Results suggest that there are qualitatively distinct classes of patients with more and less chronic depressions, and support the utility of longitudinal course as a means of parsing depression into more homogeneous subgroups. PMID:26845258

  7. Nighttime Sleep Macrostructure Is Altered in Otherwise Healthy 10-Year-Old Overweight Children

    PubMed Central

    Chamorro, Rodrigo; Algarín, Cecilia; Garrido, Marcelo; Causa, Leonardo; Held, Claudio; Lozoff, Betsy; Peirano, Patricio

    2014-01-01

    Objective Epidemiological evidence shows an inverse relationship between sleep duration and overweight/obesity risk. However, there are few polysomnographic studies that relate the organization of sleep stages to pediatric overweight (OW). We compared sleep organization in otherwise healthy OW and normal weight (NW) 10-year-old children. Subjects Polysomnographic assessments were performed in 37 NW and 59 OW children drawn from a longitudinal study beginning in infancy. Weight and height were used to evaluate body-mass index (BMI) according to international criteria. Non-REM (NREM) sleep (stages N1, N2 and N3), rapid eye movement (REM) sleep (stage R), and wakefulness (stage W) were visually scored. Sleep parameters were compared in NW and OW groups for the whole total sleep period (SPT) and for each successive third of it using independent student t-tests or non-parametric tests. The relationship between BMI and sleep variables was evaluated by correlation analyses controlling for relevant covariates. Results The groups were similar in timing of sleep onset and offset, and sleep period time. BMI was inversely related to total sleep time (TST) and sleep efficiency. OW children showed reduced TST, sleep efficiency, and stage R amount, but higher stage W amount. In analysis by thirds of the SPT, the duration of stage N3 episodes, was shorter in the first third and longer in the second third in OW children, compared with NW children. Conclusions Our results show reduced sleep amount and quality in otherwise healthy OW children. The lower stage R amount and changes involving stage N3 throughout the night suggest that OW in childhood is associated with modifications not only in sleep duration, but also in the ongoing nighttime patterns of NREM sleep and REM sleep stages. PMID:24352291

  8. Migration to the Downtown Eastside neighbourhood of Vancouver and changes in service use in a cohort of mentally ill homeless adults: a 10-year retrospective study

    PubMed Central

    Somers, Julian M; Moniruzzaman, Akm; Rezansoff, Stefanie N

    2016-01-01

    Objectives Little research has investigated the role of migration as a potential contributor to the spatial concentration of homeless people with complex health and social needs. In addition, little is known concerning the relationship between possible migration and changes in levels of service use over time. We hypothesised that homeless, mentally ill individuals living in a concentrated urban setting had migrated from elsewhere over a 10-year period, in association with significant increases in the use of public services. Setting Recruitment was concentrated in the Downtown Eastside neighbourhood of Vancouver, Canada. Participants Participants (n=433) met criteria for chronic homelessness and serious mental illness, and provided consent to access administrative data. Methods Linked administrative data were used to retrospectively examine geographic relocation as well as rates of health, justice, and social welfare service utilisation in each of the 10 years prior to recruitment. Generalised estimating equations were used to estimate the effect of migration on service use. Results Over a 10-year period there was significant movement into Vancouver's Downtown Eastside neighbourhood (from 17% to 52% of the cohort). During the same period, there were significant annual increases in community medical services (adjusted rate ratio (ARR) per year=1.08; 95% CI 1.06 to 1.10), hospital admissions (ARR=1.08; 95% CI 1.04 to 1.11), criminal convictions (ARR=1.08; 95% CI 1.03 to 1.13), and financial assistance payments (ARR=1.04; 95% CI 1.03 to 1.06). Migration was significantly associated with financial assistance, but not with other types of services. Conclusions Significant increases in service use over a 10-year period coincided with significant migration into an urban area where relevant services were concentrated. These results highlight opportunities for early intervention in spatially diverse neighbourhoods to interrupt trajectories marked by worsening health and

  9. Cleft lip and palate and related factors: A 10 years study in university hospitalised patients at Mashhad — Iran

    PubMed Central

    Noorollahian, Morteza; Nematy, Mohsen; Dolatian, Atiyeh; Ghesmati, Hengameh; Akhlaghi, Saeed; Khademi, Gholam Reza

    2015-01-01

    Background: Oral-facial clefts including cleft lip and palate are the most common congenital malformations of the head and neck. Environmental factors such as maternal hormonal disorders, use of psychiatric medications, vitamin and folic acid deficiency, hypoxia, cigarette smoking and maternal obesity and overweight can affect the incidence of these disorders. In Iran, one of the associated problems is a lack of accurate statistics regarding the present status of the patients, which can cause a disturbance in the health programmes of Ministry of Health and Medical Education. The aim of this study was to report the status of 398 cases of cleft lip and palate in Sheikh and Imam Reza Hospitals of Mashhad over a 10-year period. Materials and Methods: This retrospective descriptive study was performed using data collection method and included the evaluation of the recorded files and completing the data forms. In this study, the file records of 398 patients referring to Mashhad Sheikh and Imam Reza (P.U.H) Hospitals were studied, from the beginning of 2002 to the end of 2011; the obtained data from the files were collected and classified. Results: The highest frequency was related to cleft palate alone (40.7%); frequencies were lower regarding the cleft lip and palate and cleft lip alone (34.41% and 24.87%, respectively). Approximately, half of the patients were from rural areas of the city and had articulation disorders. Most of the patients were the first-born children of the family and their parents were consanguineously married; about one-third of the patients had a family history of the disease. Conclusion: According to the results of the present study, cleft lip is more frequent in males and cleft palate is more prevalent in females; the obtained results are consistent with the global statistics. PMID:26712297

  10. Modeling habit forms of sapphire crystals using the principles of periodic-bond-chain method

    NASA Astrophysics Data System (ADS)

    Bakholdin, S. I.; Maslov, V. N.

    2015-03-01

    The potential of the periodic-bond-chain method for calculating the sequence of manifestation of faces of corundum single crystals is considered. The leading role of the faces of the pinacoid, high rhombohedron, and hexagonal prism is demonstrated. The calculation results are compared with the experimental data on faceting the lateral surface of cylindrical sapphire single crystals grown by the Stepanov method and with the faceting data for crystals grown by the flux method and natural crystals.

  11. Comparison of Recharge Estimation Methods During a Wet Period in a Karst Aquifer.

    PubMed

    Guardiola-Albert, Carolina; Martos-Rosillo, Sergio; Pardo-Igúzquiza, Eulogio; Durán Valsero, Juan José; Pedrera, Antonio; Jiménez-Gavilán, Pablo; Liñán Baena, Cristina

    2015-01-01

    Management of water resources, implying their appropriate protection, calls for a sound evaluation of recharge. Such assessment is very complex in karst aquifers. Most methods are developed for application to detrital aquifers, without taking into account the extraordinary heterogeneity of porosity and permeability of karst systems. It is commonly recommended to estimate recharge using multiple methods; however, differences inherent to the diverse methods make it difficult to clarify the accuracy of each result. In this study, recharge was estimated in a karst aquifer working in a natural regime, in a Mediterranean-type climate, in the western part of the Sierra de las Nieves (southern Spain). Mediterranean climate regions are characterized by high inter-annual rainfall variability featuring long dry periods and short intense wet periods, the latter constituting the most important contribution to aquifer water input. This paper aims to identify the methods that provide the most plausible range of recharge rate during wet periods. Six methods were tested: the classical method of Thornthwaite-Mather, the Visual Balan code, the chloride balance method, and spatially distributed methods such as APLIS, a novel spatiotemporal estimation of recharge, and ZOODRM. The results help determine valid methods for application in the rest of the unit of study and in similar karst aquifers.

  12. Predisposing Factors, Microbial Characteristics, and Clinical Outcome of Microbial Keratitis in a Tertiary Centre in Hong Kong: A 10-Year Experience

    PubMed Central

    Ng, Alex Lap-Ki; To, Kelvin Kai-Wang; Choi, Chile Chi-Lai; Yuen, Leonard Hsu; Yim, Suk-Ming; Chan, Keith Shun-Kit; Lai, Jimmy Shiu-Ming; Wong, Ian Yat-Hin

    2015-01-01

    Purpose. To study the risk factors, microbial profile, antibiotic susceptibility pattern, and outcome for microbial keratitis over the past 10 years in a tertiary center in Hong Kong. Methods. All cases with corneal scraping performed in Queen Mary Hospital, Hong Kong from January 2004 to December 2013 were included. Clinical outcome was defined as poor if the final visual acuity (VA) was abnormal or worse than presenting VA, a major complication occurred, or therapeutic keratoplasty was required. Results. 347 scrapes were performed in the 10-year period growing 130 microorganisms (32.3% culture positive rate). Contact lens use was the commonest risk factor. The commonest isolates were coagulase-negative Staphylococcus and Pseudomonas aeruginosa. Fluoroquinolone susceptibility was tested in 47 Gram-negative bacteria with 93.6% susceptibility (100% for Pseudomonas). 90.7% of cases had good visual outcome. Multivariate logistic regression showed age (p = 0.03), trauma (p = 0.006), and ulcer size >3 mm (p = 0.039) to be independently associated with poor outcome. Conclusion. There was no shifting trend in the isolate distribution or emergence of resistant strains in our study. Contact lens wear was the commonest risk factor, with Pseudomonas being the most frequent isolate in this group. It remained 100% susceptible to fluoroquinolones and 97% cases had good visual outcome. PMID:26167295

  13. Domain decomposition method for Maxwell’s equations: Scattering off periodic structures

    NASA Astrophysics Data System (ADS)

    Schädle, Achim; Zschiedrich, Lin; Burger, Sven; Klose, Roland; Schmidt, Frank

    2007-09-01

    We present a domain decomposition approach for the computation of the electromagnetic field within periodic structures. We use a Schwarz method with transparent boundary conditions at the interfaces of the domains. Transparent boundary conditions are approximated by the perfectly matched layer method (PML). An adaptive strategy to determine optimal PML parameters is developed. Thus we can treat Wood anomalies appearing in periodic structures. We focus on the application to typical EUV lithography line masks. Light propagation within the multilayer stack of the EUV mask is treated analytically. This results in a drastic reduction of the computational costs and allows for the simulation of next generation lithography masks on a standard personal computer.

  14. Recurrent Gram-Negative Bloodstream Infection: A 10-Year Population-Based Cohort Study

    PubMed Central

    Al-Hasan, Majdi N.; Eckel-Passow, Jeanette E.; Baddour, Larry M.

    2010-01-01

    Background Recurrent gram-negative bloodstream infection (BSI) has not been evaluated in a population-based setting; therefore, we performed a population-based retrospective cohort study to examine the incidence, recurrence, and mortality rates of gram-negative BSI. Methods We identified 944 episodes of gram-negative BSI, including 98 recurrent episodes, among Olmsted County, Minnesota, residents from 1/1/1998 to 12/31/2007. Kaplan-Meier method was used to estimate the cumulative incidence rate of recurrence and 28-day all-cause mortality rate of gram-negative BSI. Cox proportional hazard regression was used to determine risk factors for recurrence. Results The overall age- and gender-adjusted incidence rate of gram-negative BSI per 100,000 person-years was 84.5 (95% confidence interval [CI]: 79.1–90.0), including 75.7 (95% CI: 70.6–80.8) for first episodes and 8.8 (95% CI: 7.1–10.6) for recurrent episodes. Among 846 patients with first episodes of gram-negative BSI, the cumulative incidence rates of recurrence after 1, 5, and 10 years of the initial episode were 5.6%, 9.2%, and 14.6%, respectively, with death treated as a competing risk. Patients with Klebsiella species were more likely than those with Escherichia coli BSI to develop recurrent gram-negative BSI (hazard ratio: 2.33 [95% CI: 1.34–3.92], p=0.003). The 28-day all-cause mortality rates following the initial and second episodes of gram-negative BSI were 10.0% (95% CI: 8.0–12.0) and 11.3% (95% CI: 4.4–18.2), respectively. Conclusions Even though recurrent gram-negative BSI was relatively uncommon in the general population, up to 15% of patients with gram-negative BSI developed a recurrent episode within 10 years of the initial episode. PMID:20378069

  15. Periodicity of flare index revisited using the Hilbert-Huang transform method

    NASA Astrophysics Data System (ADS)

    Gao, P. X.; Liang, H. F.; Zhu, W. W.

    2011-04-01

    Using the Hilbert-Huang Transform (HHT) method, we investigate the periodicity in the monthly mean flare indices from 1966 to 2007 (corresponding to almost four complete solar cycles), calculated by T. Atac and A. Ozguc. The results show as following. (1) The periods of 9.37 ± 2.53, 11.8 ± 0.172 and 23.6 ± 0.316 years are found to be statistically significant in the flare index. The most eminent period is 9.37 ± 2.53 years. (2) Other periods of 0.237 ± 0.196 years (86.6 ± 71.6 days), 0.525 ± 0.0508 years (191 ± 18.5 days), 1.05 ± 0.478 years (383 ± 174 days) and 2.37 ± 0.395 years are below the 99% confidence level line, suggesting they are due to stochastic random noise.

  16. Stochastic response and bifurcation of periodically driven nonlinear oscillators by the generalized cell mapping method

    NASA Astrophysics Data System (ADS)

    Han, Qun; Xu, Wei; Sun, Jian-Qiao

    2016-09-01

    The stochastic response of nonlinear oscillators under periodic and Gaussian white noise excitations is studied with the generalized cell mapping based on short-time Gaussian approximation (GCM/STGA) method. The solutions of the transition probability density functions over a small fraction of the period are constructed by the STGA scheme in order to construct the GCM over one complete period. Both the transient and steady-state probability density functions (PDFs) of a smooth and discontinuous (SD) oscillator are computed to illustrate the application of the method. The accuracy of the results is verified by direct Monte Carlo simulations. The transient responses show the evolution of the PDFs from being Gaussian to non-Gaussian. The effect of a chaotic saddle on the stochastic response is also studied. The stochastic P-bifurcation in terms of the steady-state PDFs occurs with the decrease of the smoothness parameter, which corresponds to the deterministic pitchfork bifurcation.

  17. Prevalence of dermatoses in dermatologic evaluation requests from patients admitted to a tertiary hospital for 10 years*

    PubMed Central

    Dantas, Lia Dias Pinheiro; Bakos, Lucio; Balbinot, Gabriela; Drechsler, Carine Elisabete Rost; Eidt, Letícia Maria

    2015-01-01

    Skin diseases are common in hospitalized patients. However, there is a lack of data concerning their frequency. The objective of this study is to evaluate the prevalence of dermatological diagnoses in hospitalized patients after consultation requested by nondermatologist physicians to the Department of Dermatology, Hospital de Clinicas de Porto Alegre period of 10 years. A total of 5685 patients were evaluated, representing an average of 48.2 patients per month. The five most frequent groups were infectious dermatoses(33.25%), eczematous dermatoses (11.49%), drug reactions (11.43%), vascular dermatoses (6.81%) and group of pruritus, prurigo nodularis and urticaria (hives) (4.71%). PMID:26560228

  18. A robust direct-integration method for rotorcraft maneuver and periodic response

    NASA Technical Reports Server (NTRS)

    Panda, Brahmananda

    1992-01-01

    The Newmark-Beta method and the Newton-Raphson iteration scheme are combined to develop a direct-integration method for evaluating the maneuver and periodic-response expressions for rotorcraft. The method requires the generation of Jacobians and includes higher derivatives in the formulation of the geometric stiffness matrix to enhance the convergence of the system. The method leads to effective convergence with nonlinear structural dynamics and aerodynamic terms. Singularities in the matrices can be addressed with the method as they arise from a Lagrange multiplier approach for coupling equations with nonlinear constraints. The method is also shown to be general enough to handle singularities from quasisteady control-system models. The method is shown to be more general and robust than the similar 2GCHAS method for analyzing rotorcraft dynamics.

  19. Semi-Periodic Sequences and Extraneous Events in Earthquake Forecasting: I. Theory and Method, Parkfield Application

    NASA Astrophysics Data System (ADS)

    Nava Pichardo, Fidencio Alejandro; Quinteros Cartaya, Claudia Beatriz; Glowacka, Ewa; Frez Cárdenas, José Duglas

    2014-07-01

    We present a new method to identify semi-periodic sequences in the occurrence times of large earthquakes, which allows for the presence of multiple semi-periodic sequences and/or events not belonging to any identifiable sequence in the time series. The method, based on the analytic Fourier transform, yields estimates of the departure from periodicity of an observed sequence, and of the probability that the sequence is not due to chance. These estimates are used to make and to evaluate forecasts of future events belonging to each sequence. Numerous tests with synthetic catalogs show that the method is surprisingly capable of correctly identifying sequences, unidentifiable by eye, in complicated time series. Correct identification of a given sequence depends on the number of events it contains, on the sequence's departure from periodicity, and, in some cases, on the choice of starting and ending times of the analyzed time window; as well as on the total number of events in the time series. Some particular data combinations may result in spectra where significant periods are obscured by large amplitudes artifacts of the transform, but artifacts can be usually recognized because they lack harmonics; thus, in most of these cases, true semi-periodic sequences may not be identified, but no false identifications will be made. A first example of an application of the method to real seismicity data is the analysis of the Parkfield event series. The analysis correctly aftcasts the September 2004 earthquake. Further applications to real data from Japan and Venezuela are shown in a companion paper.

  20. Fourier Representation Methods for Møller-Plesset Perturbation Theory in One-Dimensionally Periodic Systems

    NASA Astrophysics Data System (ADS)

    Fripiat, J. G.; Delhalle, J.; Harris, Frank E.

    2007-12-01

    Ab initio studies of one-dimensionally periodic systems are advantageously carried out by methods that employ Fourier representations and the Ewald method for accelerating the lattice sums. This communication desribes the first investigation in which these techniques have been applied at the Mo/ller-Plesset level of perturbation theory, MBPT(2). Second-order corrections to the restricted Hartree-Fock energy and energy bands are reported for H2, Be, and LiH chains, and these results are compared to direct-space extended-system and oligomer computations. The methods described herein exhibit improved convergence relative to the other methods to which they are compared.

  1. High-Dose-Rate Rotte 'Y' Applicator Brachytherapy for Definitive Treatment of Medically Inoperable Endometrial Cancer: 10-Year Results

    SciTech Connect

    Coon, Devin; Beriwal, Sushil Heron, Dwight E.; Kelley, Joseph L.; Edwards, Robert P.; Sukumvanich, Paniti; Zorn, Kristin K.; Krivak, Thomas C.

    2008-07-01

    Purpose: To assess the intermediate clinical outcomes of medically inoperable patients with endometrial cancer treated with definitive Rotte 'Y' applicator high-dose-rate brachytherapy (HDRB) over a 10-year period. Methods and Materials: Forty-nine inoperable patients were treated with HDRB from 1997 to 2007. Forty three (84%) were markedly obese (body mass index >35 kg/m{sup 2}). Thirty-one patients (63.3%) underwent two-dimensional treatment planning, whereas 18 patients (36.7%) underwent three-dimensional treatment planning. Thirty five of the patients (71.4%) were first treated with external beam radiotherapy (EBRT). For patients receiving EBRT in addition to HDRB, the median Y-applicator dose was 20 Gy in 5 fractions; for patients receiving HDRB alone it was 35 Gy in 5 fractions. All patients received two Y-applicator treatments per day. Results: Median follow-up time for all patients was 33 months. Acute HDRB toxicities were limited to Grade 1 and 2 occurring in 5 patients. One patient had a myocardial infarction. Four patients had late Grade 2 or 3 toxicity. Three patients had local recurrence (median time to recurrence, 16 months). The 3- and 5-year actuarial cause-specific survival rates were 93% and 87%, respectively; the overall survival rate was 83% and 42%, respectively, at 3 and 5 years. Conclusions: Twice-daily HDRB using a Y-applicator is a well-tolerated and efficacious regimen for the definitive treatment of medically inoperable patients with early-stage endometrial cancer. The recent incorporation of three-dimensional treatment planning has the potential to further decrease treatment morbidities.

  2. Reduction in Hospital-Wide Clinical Laboratory Specimen Identification Errors following Process Interventions: A 10-Year Retrospective Observational Study

    PubMed Central

    Ning, Hsiao-Chen; Lin, Chia-Ni; Chiu, Daniel Tsun-Yee; Chang, Yung-Ta; Wen, Chiao-Ni; Peng, Shu-Yu; Chu, Tsung-Lan; Yu, Hsin-Ming; Wu, Tsu-Lan

    2016-01-01

    Background Accurate patient identification and specimen labeling at the time of collection are crucial steps in the prevention of medical errors, thereby improving patient safety. Methods All patient specimen identification errors that occurred in the outpatient department (OPD), emergency department (ED), and inpatient department (IPD) of a 3,800-bed academic medical center in Taiwan were documented and analyzed retrospectively from 2005 to 2014. To reduce such errors, the following series of strategies were implemented: a restrictive specimen acceptance policy for the ED and IPD in 2006; a computer-assisted barcode positive patient identification system for the ED and IPD in 2007 and 2010, and automated sample labeling combined with electronic identification systems introduced to the OPD in 2009. Results Of the 2000345 specimens collected in 2005, 1023 (0.0511%) were identified as having patient identification errors, compared with 58 errors (0.0015%) among 3761238 specimens collected in 2014, after serial interventions; this represents a 97% relative reduction. The total number (rate) of institutional identification errors contributed from the ED, IPD, and OPD over a 10-year period were 423 (0.1058%), 556 (0.0587%), and 44 (0.0067%) errors before the interventions, and 3 (0.0007%), 52 (0.0045%) and 3 (0.0001%) after interventions, representing relative 99%, 92% and 98% reductions, respectively. Conclusions Accurate patient identification is a challenge of patient safety in different health settings. The data collected in our study indicate that a restrictive specimen acceptance policy, computer-generated positive identification systems, and interdisciplinary cooperation can significantly reduce patient identification errors. PMID:27494020

  3. Publication and non-publication of drug trial results: a 10-year cohort of trials in Norwegian general practice

    PubMed Central

    Brænd, Anja Maria; Straand, Jørund; Jakobsen, Rune Bruhn; Klovning, Atle

    2016-01-01

    Objectives Previously, we identified a 10-year cohort of protocols from applications to the Norwegian Medicines Agency 1998–2007, consisting of 196 drug trials in general practice. The aim of this study was to examine whether trial results were published and whether trial funding and conflicts of interest were reported. Design Cohort study of trials with systematic searches for published results. Setting Clinical drug trials in Norwegian general practice. Methods We performed systematic literature searches of MEDLINE, Embase and CENTRAL to identify publications originating from each trial using characteristics such as test drug, comparator and patient groups as search terms. When no publication was identified, we contacted trial sponsors for information regarding trial completion and reference to any publications. Main outcome measures We determined the frequency of publication of trial results and trial characteristics associated with publication of results. Results Of the 196 trials, 5 were never started. Of the remaining 191 trials, 71% had results published in a journal, 11% had results publicly available elsewhere and 18% of trials had no results available. Publication was more common among trials with an active comparator drug (χ2 test, p=0.040), with a larger number of patients (total sample size≥median, p=0.010) and with a longer trial period (duration≥median, p=0.025). Trial funding was reported in 85% of publications and increased over time, as did reporting of conflicts of interest among authors. Among the 134 main journal articles from the trials, 60% presented statistically significant results for the investigational drug, and the conclusion of the article was favourable towards the test drug in 78% of papers. Conclusions We did not identify any journal publication of results for 29% of the general practice drug trials. Trials with an active comparator, larger and longer trials were more likely to be published. PMID:27067893

  4. Antidepressant use and 10-year incident fracture risk: the population-based Canadian Multicentre Osteoporosis Study (CaMoS)

    PubMed Central

    Bernatsky, S.; Abrahamowicz, M.; Papaioannou, A.; Bessette, L.; Adachi, J.; Goltzman, D.; Prior, J.; Kreiger, N.; Towheed, T.; Leslie, W. D.; Kaiser, S.; Ioannidis, G.; Pickard, L.; Fraser, L.-A.; Rahme, E.

    2016-01-01

    Summary We used data from a large, prospective Canadian cohort to assess the association between selective serotonin reuptake inhibitors (SSRIs) and serotonin and noradrenaline reuptake inhibitors (SNRIs) and fracture. We found an increased risk of fractures in individuals who used SSRI or SNRI, even after controlling for multiple risk factors. Introduction Previous studies have suggested an association between SSRIs and increasing risk of fragility fractures. However, the majority of these studies were not long-term analyses or were performed using administrative data and, thus, could not fully control for potential confounders. We sought to determine whether the use of SSRIs and SNRIs is associated with increased risk of fragility fracture, in adults aged 50+. Methods We used data from the Canadian Multicentre Osteoporosis Study (CaMos), a prospective randomly selected population-based community cohort; our analyses focused on subjects aged 50+. Time to event methodology was used to assess the association between SSRI/SNRI use, modeled time-dependently, and fragility fracture. Results Among 6,645 subjects, 192 (2.9 %) were using SSRIs or/and SNRIs at baseline. During the 10-year study period, 978 (14.7 %) participants experienced at least one fragility fracture. In our main analysis, SSRI/SNRI use was associated with increased risk of fragility fracture (hazard ratio (HR), 1.88; 95 % confidence intervals (CI), 1.48–2.39). After controlling for multiple risk factors, including Charlson score, previous falls, and bone mineral density hip and lumbar bone density, the adjusted HR for current SSRI/SNRI use remained elevated (HR, 1.68; 95 % CI, 1.32–2.14). Conclusions Our results lend additional support to an association between SSRI/SNRI use and fragility fractures. Given the high prevalence of antidepressants use, and the impact of fractures on health, our findings may have a significant clinical impact. PMID:24566587

  5. 26 CFR 601.204 - Changes in accounting periods and in methods of accounting.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 20 2014-04-01 2014-04-01 false Changes in accounting periods and in methods of accounting. 601.204 Section 601.204 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601.204 Changes in accounting...

  6. Method of electric field flow fractionation wherein the polarity of the electric field is periodically reversed

    DOEpatents

    Stevens, Fred J.

    1992-01-01

    A novel method of electric field flow fractionation for separating solute molecules from a carrier solution is disclosed. The method of the invention utilizes an electric field that is periodically reversed in polarity, in a time-dependent, wave-like manner. The parameters of the waveform, including amplitude, frequency and wave shape may be varied to optimize separation of solute species. The waveform may further include discontinuities to enhance separation.

  7. Reaching Spanish-speaking smokers online: a 10-year worldwide research program

    PubMed Central

    Muñoz, Ricardo Felipe; Chen, Ken; Bunge, Eduardo Liniers; Bravin, Julia Isabela; Shaughnessy, Elizabeth Annelly; Pérez-Stable, Eliseo Joaquín

    2014-01-01

    Objective To describe a 10-year proof-of-concept smoking cessation research program evaluating the reach of online health interventions throughout the Americas. Methods Recruitment occurred from 2002–2011, primarily using Google.com AdWords. Over 6 million smokers from the Americas entered keywords related to smoking cessation; 57 882 smokers (15 912 English speakers and 41 970 Spanish speakers) were recruited into online self-help automated intervention studies. To examine disparities in utilization of methods to quit smoking, cessation aids used by English speakers and Spanish speakers were compared. To determine whether online interventions reduce disparities, abstinence rates were also compared. Finally, the reach of the intervention was illustrated for three large Spanish-speaking countries of the Americas—Argentina, Mexico, and Peru—and the United States of America. Results Few participants had utilized other methods to stop smoking before coming to the Internet site; most reported using no previous smoking cessation aids: 69.2% of Spanish speakers versus 51.8% of English speakers (P < 0.01). The most used method was nicotine gum, 13.9%. Nicotine dependence levels were similar to those reported for in-person smoking cessation trials. Overall observed quit rate for English speakers was 38.1% and for Spanish speakers, 37.0%; quit rates in which participants with missing data were considered to be smoking were 11.1% and 10.6%, respectively. Neither comparison was significantly different. Conclusions The systematic use of evidence-based Internet interventions for health problems could have a broad impact throughout the Americas, at little or no cost to individuals or to ministries of health. PMID:25211569

  8. Extending the TIME concept: what have we learned in the past 10 years?(*).

    PubMed

    Leaper, David J; Schultz, Gregory; Carville, Keryln; Fletcher, Jacqueline; Swanson, Theresa; Drake, Rebecca

    2012-12-01

    The TIME acronym (tissue, infection/inflammation, moisture balance and edge of wound) was first developed more than 10 years ago, by an international group of wound healing experts, to provide a framework for a structured approach to wound bed preparation; a basis for optimising the management of open chronic wounds healing by secondary intention. However, it should be recognised that the TIME principles are only a part of the systematic and holistic evaluation of each patient at every wound assessment. This review, prepared by the International Wound Infection Institute, examines how new data and evidence generated in the intervening decade affects the original concepts of TIME, and how it is translated into current best practice. Four developments stand out: recognition of the importance of biofilms (and the need for a simple diagnostic), use of negative pressure wound therapy (NPWT), evolution of topical antiseptic therapy as dressings and for wound lavage (notably, silver and polyhexamethylene biguanide) and expanded insight of the role of molecular biological processes in chronic wounds (with emerging diagnostics and theranostics). Tissue: a major advance has been the recognition of the value of repetitive and maintenance debridement and wound cleansing, both in time-honoured and novel methods (notably using NPWT and hydrosurgery). Infection/inflammation: clinical recognition of infection (and non infective causes of persisting inflammation) is critical. The concept of a bacterial continuum through contamination, colonisation and infection is now widely accepted, together with the understanding of biofilm presence. There has been a return to topical antiseptics to control bioburden in wounds, emphasised by the awareness of increasing antibiotic resistance. Moisture: the relevance of excessive or insufficient wound exudate and its molecular components has led to the development and use of a wide range of dressings to regulate moisture balance, and to protect

  9. Extending the TIME concept: what have we learned in the past 10 years?(*).

    PubMed

    Leaper, David J; Schultz, Gregory; Carville, Keryln; Fletcher, Jacqueline; Swanson, Theresa; Drake, Rebecca

    2012-12-01

    The TIME acronym (tissue, infection/inflammation, moisture balance and edge of wound) was first developed more than 10 years ago, by an international group of wound healing experts, to provide a framework for a structured approach to wound bed preparation; a basis for optimising the management of open chronic wounds healing by secondary intention. However, it should be recognised that the TIME principles are only a part of the systematic and holistic evaluation of each patient at every wound assessment. This review, prepared by the International Wound Infection Institute, examines how new data and evidence generated in the intervening decade affects the original concepts of TIME, and how it is translated into current best practice. Four developments stand out: recognition of the importance of biofilms (and the need for a simple diagnostic), use of negative pressure wound therapy (NPWT), evolution of topical antiseptic therapy as dressings and for wound lavage (notably, silver and polyhexamethylene biguanide) and expanded insight of the role of molecular biological processes in chronic wounds (with emerging diagnostics and theranostics). Tissue: a major advance has been the recognition of the value of repetitive and maintenance debridement and wound cleansing, both in time-honoured and novel methods (notably using NPWT and hydrosurgery). Infection/inflammation: clinical recognition of infection (and non infective causes of persisting inflammation) is critical. The concept of a bacterial continuum through contamination, colonisation and infection is now widely accepted, together with the understanding of biofilm presence. There has been a return to topical antiseptics to control bioburden in wounds, emphasised by the awareness of increasing antibiotic resistance. Moisture: the relevance of excessive or insufficient wound exudate and its molecular components has led to the development and use of a wide range of dressings to regulate moisture balance, and to protect

  10. A 10-year longitudinal fMRI study of narrative comprehension in children and adolescents.

    PubMed

    Szaflarski, Jerzy P; Altaye, Mekibib; Rajagopal, Akila; Eaton, Kenneth; Meng, Xiangxiang; Plante, Elena; Holland, Scott K

    2012-11-15

    Comprehension of spoken narratives requires coordination of multiple language skills. As such, for normal children narrative skills develop well into the school years and, during this period, are particularly vulnerable in the face of brain injury or developmental disorder. For these reasons, we sought to determine the developmental trajectory of narrative processing using longitudinal fMRI scanning. 30 healthy children between the ages of 5 and 18 enrolled at ages 5, 6, or 7, were examined annually for up to 10 years. At each fMRI session, children were presented with a set of five, 30s-long, stories containing 9, 10, or 11 sentences designed to be understood by a 5 year old child. fMRI data analysis was conducted based on a hierarchical linear model (HLM) that was modified to investigate developmental changes while accounting for missing data and controlling for factors such as age, linguistic performance and IQ. Performance testing conducted after each scan indicated well above the chance (p<0.002) comprehension performance. There was a linear increase with increasing age in bilateral superior temporal cortical activation (BAs 21 and 22) linked to narrative processing. Conversely, age-related decreases in cortical activation were observed in bilateral occipital regions, cingulate and cuneus, possibly reflecting changes in the default mode networks. The dynamic changes observed in this longitudinal fMRI study support the increasing role of bilateral BAs 21 and 22 in narrative comprehension, involving non-domain-specific integration in order to achieve final story interpretation. The presence of a continued linear development of this area throughout childhood and teenage years with no apparent plateau, indicates that full maturation of narrative processing skills has not yet occurred and that it may be delayed to early adulthood.

  11. Haiti's progress in achieving its 10-year plan to eliminate cholera: hidden sickness cannot be cured.

    PubMed

    Koski-Karell, Victoria; Farmer, Paul E; Isaac, Benito; Campa, Elizabeth M; Viaud, Loune; Namphy, Paul C; Ternier, Ralph; Ivers, Louise C

    2016-01-01

    Since the beginning of the cholera epidemic in Haiti 5 years ago, the prevalence of this deadly water-borne disease has fallen far below the initial rates registered during its explosive outset. However, cholera continues to cause extensive suffering and needless deaths across the country, particularly among the poor. The urgent need to eliminate transmission of cholera persists: compared to the same period in 2014, the first 4 months of 2015 saw three times the number of cholera cases. Drawing upon epidemiology, clinical work (and clinical knowledge), policy, ecology, and political economy, and informed by ethnographic data collected in a rural area of Haiti called Bocozel, this paper evaluates the progress of the nation's 10-year Plan for the Elimination of Cholera. Bocozel is a rice-producing region where most people live in extreme poverty. The irrigation network is decrepit, the land is prone to environmental shocks, fertilizer is not affordable, and the government's capacity to assist farmers is undermined by resource constraints. When peasants do have rice to sell, the price of domestically grown rice is twice that of US-imported rice. Canal water is not only used to irrigate thousands of acres of rice paddies and sustain livestock, but also to bathe, wash, and play, while water from wells, hand pumps, and the river is used for drinking, cooking, and bathing. Only one out of the three government-sponsored water treatment stations in the research area is still functional and utilized by those who can afford it. Latrines are scarce and often shared by up to 30 people; open defecation remains common. Structural vulnerabilities cut across all sectors - not just water, sanitation, health care, and education, but agriculture, environment, (global and local) commerce, transportation, and governance as well. These are among the hidden sicknesses that impede Haiti and its partners' capacity to eliminate cholera. PMID:27307774

  12. A 10-year spatial and temporal trend of sulfate across the United States

    NASA Astrophysics Data System (ADS)

    Malm, William C.; Schichtel, Bret A.; Ames, Rodger B.; Gebhart, Kristi A.

    2002-11-01

    Legislative and regulatory mandates have resulted in reduced sulfur dioxide (SO2) emissions in both the eastern and western United States with anticipation that concurrent levels of ambient SO2, SO42-, and rainwater acidity would decrease. This paper examines spatial and temporal trends in ambient SO42- concentration from 1988 to 1999, SO2 emissions from 1990 to 1999, and the relationship between these two variables. The SO42- concentration data came from combining data from the Interagency Monitoring of Protected Visual Environments (IMPROVE) and the Clean Air Status and Trends Network (CASTNet). Over 70 sites spread across the continental United States are considered in this analysis. From a spatial perspective, the 90th percentile summer sulfate concentrations are highest along the Ohio River Valley and in central Tennessee where the emission density of SO2 is greatest. These concentrations are a factor of 2 greater than the Northeast, northern Michigan, and coastal areas of the Southeast and about a factor of 15 greater than the central western United States. In the East, the largest SO42- decreases in the 80th percentile concentrations occurred north of the Ohio River Valley, while most monitoring sites south of Kentucky and Virginia showed increasing and decreasing trends that were not statistically significant. Big Bend National Park, Texas, Cranberry, North Carolina, and Lassen Volcanic National Park, California, are the only areas that show a statistically significant increase in SO42- mass concentrations. The 1990-1999 annual 80th percentile SO42- time series were compared to the annual SO2 emissions over four broad United States regions. Each region had a unique time series pattern with the SO42- concentrations and SO2 emissions closely tracking each other over the 10-year period. Both the SO42- and SO2 emissions decreased in the Northeast (28%) and the West (15%), while there was little change in the Southeast and a 15% increase over Texas, New Mexico

  13. Haiti's progress in achieving its 10-year plan to eliminate cholera: hidden sickness cannot be cured.

    PubMed

    Koski-Karell, Victoria; Farmer, Paul E; Isaac, Benito; Campa, Elizabeth M; Viaud, Loune; Namphy, Paul C; Ternier, Ralph; Ivers, Louise C

    2016-01-01

    Since the beginning of the cholera epidemic in Haiti 5 years ago, the prevalence of this deadly water-borne disease has fallen far below the initial rates registered during its explosive outset. However, cholera continues to cause extensive suffering and needless deaths across the country, particularly among the poor. The urgent need to eliminate transmission of cholera persists: compared to the same period in 2014, the first 4 months of 2015 saw three times the number of cholera cases. Drawing upon epidemiology, clinical work (and clinical knowledge), policy, ecology, and political economy, and informed by ethnographic data collected in a rural area of Haiti called Bocozel, this paper evaluates the progress of the nation's 10-year Plan for the Elimination of Cholera. Bocozel is a rice-producing region where most people live in extreme poverty. The irrigation network is decrepit, the land is prone to environmental shocks, fertilizer is not affordable, and the government's capacity to assist farmers is undermined by resource constraints. When peasants do have rice to sell, the price of domestically grown rice is twice that of US-imported rice. Canal water is not only used to irrigate thousands of acres of rice paddies and sustain livestock, but also to bathe, wash, and play, while water from wells, hand pumps, and the river is used for drinking, cooking, and bathing. Only one out of the three government-sponsored water treatment stations in the research area is still functional and utilized by those who can afford it. Latrines are scarce and often shared by up to 30 people; open defecation remains common. Structural vulnerabilities cut across all sectors - not just water, sanitation, health care, and education, but agriculture, environment, (global and local) commerce, transportation, and governance as well. These are among the hidden sicknesses that impede Haiti and its partners' capacity to eliminate cholera.

  14. Comparative analysis of computational methods for periodic transonic flows at low and high frequencies

    NASA Astrophysics Data System (ADS)

    Mohaghegh, M. R.; Malek-Jafarian, M.

    2015-12-01

    This paper presents a comparative analysis via simulation of time-periodic unsteady inviscid flow at low and high frequencies using Time Spectral Method (TSM) and comparing it with the traditional methods such as BDF and Explicit Structured Adaptive Grid Method. The TSM uses a Fourier representation in time. Mathematical tools used here are discrete Fourier transformations. The TSM has been proposed for the fast and efficient computation of periodic unsteady flows. This method has been evaluated and has been validated with NACA pitching airfoils that are widely used and prevalent 2D external aerodynamics test cases. To validate the results presented by the TSM are compared with experimental data and two the other methods. It shows a significant reduction in the computational expense compared to the conventional time-accurate methods, due to taking advantage of the periodic nature of flow by Fourier representation for temporal discretization that has a high accuracy. Also it has shown that TSM can be applied accurately for ample rang of variations of frequency (NACA 64A010 (CT6)) and variations in angle of attacks (NACA 0012 (CT1)).

  15. Aggression and Violence among Iranian Adolescents and Youth: A 10-year Systematic Review

    PubMed Central

    Sadeghi, Saeid; Farajzadegan, Ziba; Kelishadi, Roya; Heidari, Kamal

    2014-01-01

    Background: Although the overwhelming majority of Iranian adolescents are well-adjusted, a substantial group exhibits high levels of maladjustment and deficient functioning. Escalation of criminal violence among the youth population has become a major public policy issue and a serious public health problem. In reviewing a 10-year literature, this article aimed to describe and propose primary assumptions regarding the correlates of aggressive and violent behaviors in Iranian adolescents and youth. Methods: Bibliographic databases such as PubMed and Google Scholar along with Iranian databases including PubMed, IranMedex, Magiran, Irandoc, Psychoinfo, and Emrofor Scientific Information Database, and Magiran constituted the databases which we searched for the relevant literature. Overall 98 articles met the inclusion criteria, allowing us to initiate the discussion. Results: Reportedly, prevalence of violence and aggression among the Iranian adolescents and youth ranged from 30% to 65.5% while males being 2½ times more affected than females. The role of gender, family environment, family size, socioeconomic status, and victimization in perpetuating the circumstances was apparent. Conclusions: Relatively high prevalence of violence and aggression among Iranian youth and adolescents is a warning sign and a great challenge to the social system. Reviewed studies suffer from certain methodological and conceptual limitations. Undertaking community-based studies to estimate the actual extent of the problem is warranted. PMID:26157572

  16. Inhibitory control in otherwise healthy overweight 10-year-old children

    PubMed Central

    Reyes, S; Peirano, P; Peigneux, P; Lozoff, B; Algarin, C

    2015-01-01

    BACKGROUND Preventing obesity is a worldwide public health priority. In vulnerable children living in obesogenic environments, with easy access to high-caloric food, alterations in inhibitory control functions might favor excessive food intake and affect energy regulation. We hypothesized that overweight/obese children would present lower inhibitory control in comparison to normal weight children. METHODS We measured inhibitory control functions in 93 otherwise healthy overweight/obese and 92 normal weight 10-year-old children using the Stroop test and the Go/No-Go task. Event-related potentials were recorded during the Go/No-Go task. RESULTS Overweight/obese children showed slower reaction times (1248.6 ms (95% confidence interval (CI): 1182.9–1314.3) vs 1149.0 ms (95% CI: 1083.0–1215.1)) on the Stroop test, higher reaction time variability (0.25 (95% CI: 0.22–0.27) vs 0.21 (95% CI: 0.19–0.24)) on the Go/No-Go task and decreased P300 amplitude (4.1 µV (95% CI: 3.0–5.2) vs 6.4 µV (95% CI: 5.2–7.6)) on event-related potentials compared with normal weight children. CONCLUSIONS Our results indicate altered inhibitory control functions in otherwise healthy overweight/obese children, which might contribute to their excessive food consumption. PMID:25869603

  17. Depression Amplifies the Influence of Central Obesity on 10-Year Incidence of Diabetes: Findings from MIDUS

    PubMed Central

    Karlamangla, Arun

    2016-01-01

    Background Central obesity is a major risk factor for diabetes but many obese individuals never develop diabetes, suggesting the presence of important effect modifiers. Depression has emerged as a key risk factor for poor glycemic control, but to our knowledge, no previous work has investigated whether depression amplifies the effect of central obesity on glucoregulation. Methods and Findings We used a national sample of adults without prevalent diabetes (MIDUS; N = 919) to test for synergy between central obesity and depression in the development of diabetes 10 years later. We found that depression amplified the association of waist-to-hip ratio (WHR) with incident diabetes adjusted for age, race, gender, education, physical activity, and sleep problems (p = 0.01 for test of interaction). The relative risk for incident diabetes per every 0.1 increment in WHR was 1.75 (95% CI: 1.31; 2.33) in those without depression and 3.78 in those with depression (95% CI: 2.14; 6.66). Conclusions These results confirm the role of depression as a robust risk factor for the development of diabetes and for the first time, demonstrate a synergy between depression and central obesity. Identifying and addressing depression could prove to be an effective approach to preventing diabetes in at risk individuals. Ultimately, elucidating the interplay among risk factors from different domains will be key to understanding multifactorial diseases such as diabetes and informing theory-based, patient-centered interventions aimed at reducing diabetes risk. PMID:27755576

  18. The paediatric flat foot and general anthropometry in 140 Australian school children aged 7 - 10 years

    PubMed Central

    2011-01-01

    Background Many studies have found a positive relationship between increased body weight and flat foot posture in children. Methods From a study population of 140 children aged seven to 10 years, a sample of 31 children with flat feet was identified by screening with the FPI-6. Basic anthropometric measures were compared between subjects with and without flat feet as designated. Results The results of this study, in contrast to many others, question the association of flat feet and heavy children. A significant relationship between foot posture and weight (FPI (L) r = -0.186 (p < 0.05), FPI(R) r = -0.194 (p < 0.05), waist girth (FPI (L) r = -0.213 (p < 0.05), FPI(R) r = -0.228 (p < 0.01) and BMI (FPI (L) r = -0.243 (p < 0.01), FPI(R) r = -0.263 (p < 0.01) was identified, but was both weak and inverse. Conclusions This study presents results which conflict with those of many previous investigations addressing the relationship between children's weight and foot posture. In contrast to previous studies, the implication of these results is that heavy children have less flat feet. Further investigation is warranted using a standardized approach to assessment and a larger sample of children to test this apparent contradiction. PMID:21513507

  19. Annual and interannual variations of Earth-emitted radiation based on a 10-year data set

    NASA Technical Reports Server (NTRS)

    Bess, T. Dale; Smith, G. Louis; Charlock, Thomas P.; Rose, Fred G.

    1989-01-01

    The method of empirical orthogonal functions (EOF) was applied to a 10-year data set of outgoing longwave radiation. Spherical harmonic functions are used as a basis set for producing equal area map results. The following findings are noted. The first EOF accounts for 66 percent of the variance. After that, each EOF accounts for only a small variance, forming a slowly converging series. The first two EOF's describe mainly the annual cycle. The third EOF is primarily the semiannual cycle although many other EOF's also contain significant semiannual parts. These results reaffirm those based on a shorter data set. In addition, a much stronger spring/fall mode was found in the central equatorial Pacific Ocean for the second EOF than was found earlier. This difference is attributed to the use of broadband radiometer data which were available for the present study. The earlier study used data from a window channel instrument which is not as sensitive to water vapor variations. The fourth EOF describes much of the 1976 to 1977 and 1982 to 1983 ENSO phenomena. There is typically a gap in the spectrum between a semiannual peak and the annual cycle for all but the first EOF. A semiannual OLR dipole straddles the Asian-Australian monsoon track.

  20. High-Fidelity Generalization Method of Cells for Inelastic Periodic Multiphase Materials

    NASA Technical Reports Server (NTRS)

    Aboudi, Jacob; Pindera, Marek-Jerzy; Arnold, Steven M.

    2002-01-01

    An extension of a recently-developed linear thermoelastic theory for multiphase periodic materials is presented which admits inelastic behavior of the constituent phases. The extended theory is capable of accurately estimating both the effective inelastic response of a periodic multiphase composite and the local stress and strain fields in the individual phases. The model is presently limited to materials characterized by constituent phases that are continuous in one direction, but arbitrarily distributed within the repeating unit cell which characterizes the material's periodic microstructure. The model's analytical framework is based on the homogenization technique for periodic media, but the method of solution for the local displacement and stress fields borrows concepts previously employed by the authors in constructing the higher-order theory for functionally graded materials, in contrast with the standard finite-element solution method typically used in conjunction with the homogenization technique. The present approach produces a closed-form macroscopic constitutive equation for a periodic multiphase material valid for both uniaxial and multiaxial loading. The model's predictive accuracy in generating both the effective inelastic stress-strain response and the local stress said inelastic strain fields is demonstrated by comparison with the results of an analytical inelastic solution for the axisymmetric and axial shear response of a unidirectional composite based on the concentric cylinder model, and with finite-element results for transverse loading.

  1. Relationship Status Predicts Lower Restrictive Eating Pathology for Bisexual and Gay Men across 10-year Follow-up

    PubMed Central

    Brown, Tiffany A.; Keel, Pamela K.

    2015-01-01

    Objective Cross-sectional studies support that bisexual and gay (BG) men are at increased risk for eating pathology, and romantic relationships may buffer against risk; however, no studies have examined this association longitudinally. The current study examined how romantic relationships impact the trajectory of eating pathology in BG versus heterosexual men. Method BG (n=51) and heterosexual (n=522) men completed surveys of health and eating behaviors at baseline and 10-year follow-up. Results For BG men, being single at baseline prospectively predicted an increase in Drive for Thinness scores over 10-year follow-up. Additionally, for BG men in relationships at baseline, lower relationship satisfaction predicted an increase in Drive for Thinness scores over time. Conversely, these relationship variables did not predict trajectory of eating pathology for heterosexual men. Discussion Implications for theoretical models of risk, including objectification theory and sexual minority stress theory, and prevention, including peer-led cognitive dissonance based interventions, are discussed. PMID:26172055

  2. Ciguatera fish poisoning in Hong Kong--a 10-year perspective on the class of ciguatoxins.

    PubMed

    Wong, Chun-Kwan; Hung, Patricia; Lo, Janice Y C

    2014-08-01

    The present study used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to investigate retrospectively ciguatoxin (CTX)-positive samples as determined by mouse bioassay (MBA) in the past 10 years in Hong Kong. The results showed that Pacific CTXs (P-CTX-1, -2 and -3) were the most commonly observed toxins found in the samples, indicating Pacific Ocean areas as the most important origin of ciguatera fish poisoning. Clinical diagnosis from ciguatera patients also revealed the predominance of neurological illnesses in most cases, supporting intoxication of Pacific origin. This study demonstrated the ability of laboratory analysis to identify and quantify Pacific CTXs in suspected fish samples, so as to support the clinical diagnosis of ciguatera. Comparative analysis (Student's t-test and Spearman's rank correlation analysis) on the two CTX detection methods showed approximate linearity for overall P-CTXs (P-CTX-1, -2 and -3)/P-CTX-1 alone as derived by LC-MS/MS and total toxicity levels (P-CTX-1 equivalent) as determined by MBA. The LC-MS/MS method coupled with the rapid extraction method could allow the detection of trace amount of CTXs at levels below the clinically relevant limit, 0.1 ppb P-CTX-1 in fish flesh. For practical application, the adoption of a two-tiered approach for testing, chemical analysis by LC-MS/MS for toxic fish screening, coupled with biological assay by MBA for final toxicity confirmation, was proposed for first-line screening of CTX in potentially contaminated fish samples in the market, with an aim to minimizing the use of laboratory mice and at the same time providing reasonably effective means for routine analysis.

  3. Experience from 10 years of full-scale operation with enhanced biological phosphorus removal at Oresundsverket.

    PubMed

    Tykesson, E; Jönsson, L E; la Cour Jansen, J

    2005-01-01

    Ten years of full-scale experience with enhanced biological phosphorus removal (EBPR) has been evaluated. During the start-up period lack of carbon source was the main operational problem and a higher level of volatile fatty acids was secured by introducing a primary sludge hydrolysis. Acidic thermal sludge hydrolysis was used as the sludge treatment method at the plant during about three years. One effluent stream, rich in carbon and precipitant, was brought back to the process leading to an improvement of the phosphorus removal both by an improved biological process and chemical precipitation. A quite stable process of EBPR was developed with low levels of effluent phosphorus concentration. Stringent effluent discharge limits during short evaluation periods necessitated a continued work for improvement of the short-term stability. During periods with lack of carbon, such as industrial holiday or rainy periods, both simultaneous precipitation and reduced aeration have been successfully tested as strategies for securing low levels of effluent phosphorus.

  4. Acute paediatric bite injuries treated on inpatient basis: a 10-year retrospective study and criteria for hospital admission.

    PubMed

    Shipkov, Hristo; Stefanova, Penka; Sirakov, Vladimir; Stefanov, Rumen; Dachev, Dimitar; Simeonov, Martin; Ivanov, Biser; Nenov, Momchil

    2013-12-01

    The aim of this study was to evaluate the acute bite wounds in children treated on an inpatient basis over a 10-year period and the criteria for inpatient treatment. This study comprised all acute mammalian bite injuries in relation to all paediatric bite injuries seen at the Emergency Surgical Department (ESD). Inclusion criteria were: aged between 0-18 years; acute human or animal bite injuries (presenting for the first time); and inpatient treatment. Exclusion criteria were: bite wounds treated elsewhere and referred for complications; bites treated on an outpatient basis referred for complications; and all insect bites. Over 10 years, 12,948 children were seen at the ESD. There were 167 children (0.77%) with mammalian bite wounds. Twelve of them responded to the inclusion criteria. They presented 7.18% of all mammalian bite injuries and 0.09% of all paediatric emergency visits at the ESD. The average age was 3.82 ± 1.63 years (from 1.3-7 years). The time elapsed between the accident to the wound debridement was 118.64 ± 101.39 minutes. There were 10 dogs, one horse, and one rabbit bite. Surgical treatment comprised debridement, saline irrigation, and primary closure or reconstruction. All patients received antibiotics in the postoperative period. The average hospital stay was 5.92 ± 2.39 days. In one case a partial distal flap necrosis occurred. Animal bite injuries treated on an inpatient basis are predominantly dog bites in young children under 10 years of age, with deep, extended, and commonly multiple injuries. Only 7% of paediatric bite injuries require inpatient treatment.

  5. Alternative exact method for random walks on finite and periodic lattices with traps

    NASA Astrophysics Data System (ADS)

    Soler, Jose M.

    1982-07-01

    An alternative general method for random walks in finite or periodic lattices with traps is presented. The method gives, in a straightforward manner and in very little computing time, the exact probability that a random walker, starting from a given site, will undergo n steps before trapping. Another version gives the probability that the walker is at any other given position after n steps. The expected walk lengths calculated for simple lattices agree exactly with those given by a previous exact method by Walsh and Kozak.

  6. Long-Term Results after Placement of Aortic Bifurcation Self-Expanding Stents: 10 Year Mortality, Stent Restenosis, and Distal Disease Progression

    SciTech Connect

    Houston, J. Graeme Bhat, Raj; Ross, Rose; Stonebridge, Peter A.

    2007-02-15

    Purpose. To retrospectively evaluate the 10 year follow-up results in patients who had 'kissing' self-expanding stent aortic bifurcation reconstruction. Methods. Forty-three patients were treated with 'kissing' self-expanding stents for aortoiliac occlusive disease. Early follow-up with clinical and ankle brachial pressure indices (ABPI) was performed at 3, 6, 12, and 24 months and with intra-arterial digital subtraction angiography at 12-24 months; clinical and angiographic follow-up was performed for symptom recurrence up to 10 years after treatment. Retrospective record review was performed to assess mortality, clinical patency, angiographic patency, and secondary assisted patency of both stents and downstream peripheral vessels at 5 and 10 years follow-up. Results. The 2 year primary angiographic and secondary assisted stent patencies were 89% and 93%, respectively. At 10 years follow-up in 40 patients the mortality was 38% (due to myocardial infarction, stroke, chronic renal failure, malignancy, and liver failure). At 5 and 10 years follow-up the primary clinical stent patency was 82% and 68%, and the secondary assisted stent patency 93% and 86%, respectively. At 5 and 10 years, the distal vessel patency was 86% and 72%, and the secondary assisted distal vessel patency treated by surgical or endovascular techniques was 94% and 88%, respectively. At 10 years there was no limb loss. Conclusion. The long-term (10 year) results of aortic bifurcation arterial self-expanding stent placement in patients with arterial occlusive disease show a 10 year primary stent patency rate of 68% but a secondary assisted patency rate of 86%. In addition there is a high overall mortality due to other cardiovascular causes and the rate of distal disease progression and loss of patency is similar to the loss of stent patency rate.

  7. The nucleonic matter LOCV calculations in a periodic box versus the FHNC method

    NASA Astrophysics Data System (ADS)

    Modarres, M.; Tafrihi, A.

    2013-10-01

    The lowest order constrained variational (LOCV) method is reformulated for a fixed number of nucleons in a period box (PBLOCV) with the inter-nucleon interactions such as the Bethe homework potential, vB, and the scalar (v4) part of the Argonne interaction (. The two-body cluster approximation is used in the (PB)LOCV formalism to obtain the energy per particle subjected to the normalization constraint for an infinite (a finite) number of nucleons. It is shown that our (PB)LOCV results are reasonably consistent with those of Fantoni and Schmidt (Periodic-Box) Fermi HyperNetted Chain ((PB)FHNC) calculations. In addition, unlike the thermodynamic limit, it is found that the normalization constraint in the periodic box is not exactly satisfied. However, it is realized that, by increasing the number of particles, the value of normalization constraint in the periodic box improves. Therefore, the two-body cluster approximation in the PBLOCV method becomes more reliable in the larger periodic boxes than the smaller ones. On the other hand, the PBLOCV energy per particle approaches the corresponding LOCV prediction for the large number of particles. The anisotropic behavior of the PB two-body distribution function, which is one of the main point of this report, is discussed. Finally, it is found that the PBLOCV results, i.e. the total (two-body cluster) energy and the normalization constraint, similar to the PBFHNC calculations depend on the number of particles in the periodic box and this dependence principally becomes negligible for the large number of particles.

  8. Carbodiimide or periodate method to prepare peroxidase hydrazide for its use in immunoassay.

    PubMed

    Shrivastav, Tulsidas G

    2004-01-01

    Peroxidase hydrazides were prepared by conjugating horseradish peroxidase (HRP) to adipic acid dihydrazide (ADH) by carbodiimide or periodate oxidation method. The resulting HRP hydrazides (ADH-HRP) were conjugated to cortisol-21-hemisuccinate (cortisol-21-HS) by forming diimide bonds using the N-hydroxysuccinimide (NHS) carbodiimide mediated reaction. The prepared cortisol-21-HS-ADH-HRP enzyme conjugates were utilized for the development of an enzyme linked immunosorbent assay (ELISA) for direct estimation of cortisol. To the cortisol antibody coated microtiter wells, standard or serum sample (50 microL), along with 100 microL of cortisol-21-HS-ADH-HRP enzyme conjugate (ADH-HRP used is prepared by either carbodiimide or periodate oxidation method), was incubated for 1 hr at 37 degrees C. Bound enzyme activity was measured by using tetramethyl benzidine/hydrogen peroxide (TMB/H202) as substrate. The sensitivity, specificity, and recovery of the assays were found to be identical when ELISAs were employed with cortisol enzyme conjugates prepared by conjugating cortisol-21-HS to HRP hydrazide, made either by the carbodiimide method or periodate oxidation method. PMID:15461389

  9. 10 years after rio-concepts on the contribution of chemistry to a sustainable development.

    PubMed

    Eissen, Marco; Metzger, Jürgen O; Schmidt, Eberhard; Schneidewind, Uwe

    2002-02-01

    The principles of the United Nations Conference on Environment and Development (UNCED), held in June 1992 in Rio de Janeiro, and Agenda 21, the comprehensive plan of action for the 21st century, adopted 10 years ago by more than 170 governments, address the pressing problems of today and also aim at preparing the world for the challenges of this century. The conservation and management of resources for development are the main focus of interest, to which the sciences will have to make a considerable contribution. Natural, economic, and social sciences will have to be integrated in order to achieve this aim. In their future programs, the associations of the chemical industries in Europe, Japan, and the USA have explicitly accepted their obligation to foster a sustainable development. In this review we investigate innovations in chemistry exemplarily for such a development with regard to their ecological, economical, and social dimensions from an integrated and interdisciplinary perspective. Since base chemicals are produced in large quantities and important product lines are synthesized from them, their resource-saving production is especially important for a sustainable development. This concept has been shown, amongst others, by the example of the syntheses of propylene oxide and adipic acid. In the long run, renewable resources that are catalytically processed could replace fossil raw materials. Separation methods existing today must be improved considerably to lower material and energy consumption. Chemistry might become the pioneer of an innovative energy technique. The design of chemical products should make possible a sustainable processing and recycling and should prevent their bio-accumulation. Methods and criteria to assess their contribution to a sustainable development are necessary. The time taken to introduce the new more sustainable processes and products has to be diminished by linking their development with operational innovation management and with

  10. An adequacy evaluation of a 10-year, four-country nutrition and health programme

    PubMed Central

    Berti, Peter R; Mildon, Alison; Siekmans, Kendra; Main, Barbara; MacDonald, Carolyn

    2010-01-01

    Background Evaluations of large-scale health and nutrition programmes in developing countries are needed for determining the effectiveness of interventions. This article critically analyses a non-governmental organization (NGO)-led large-scale, multi-country, 10-year micronutrient and health (MICAH) programme with an ‘adequacy evaluation’, that is, a documentation of time trends in the expected direction. Methods MICAH was implemented from 1996 to 2005 in selected areas of Ethiopia, Ghana, Malawi and Tanzania, reaching >6 million people with numerous health and nutrition interventions. Coverage and impact were monitored through surveys at baseline, midpoint and end of funding. The data were subjected to post-hoc methods of quality determination, and, if of suitable quality, included in the adequacy evaluation. Results Most collected data were of moderate or high quality and therefore included in the adequacy evaluation. There were moderate to large improvements in vitamin A status in Ethiopian school-age children, children <5 years of age in Tanzania and Ghana and mothers in Ghana. Iodine status improved in Malawi and Tanzania. Anaemia rates and malaria prevalence decreased in women, pregnant women and pre-school children in Ghana, Malawi and Tanzania, but anaemia increased in Ethiopian women. Large increases were reported for rates of exclusive breastfeeding and immunization. Child growth improved to the maximum that would be predicted with the given interventions. Conclusions Numerous nutrition and health impacts were observed in the intervention areas, often of a magnitude equal to or larger than observed in controlled interventions or trials. These results show the value of integrated long-term interventions. PMID:20202929

  11. Effect of Training School Teachers on Oral Hygiene Status of 8-10 Years Old Government School Children of Udaipur City, India

    PubMed Central

    Bhat, Nagesh; Asawa, Kailash; Tak, Mridula; Singh, Anukriti; Shinde, Kushal; Gandhi, Neha; Doshi, Astha

    2016-01-01

    Introduction Provision of oral health knowledge to the children by their teachers at the school level can prove to be more fruitful because it is the time period during which the children begin to learn the basic oral hygiene practices and are most prone to dental caries. Aim This study was carried out to assess the effect of training school teachers on oral hygiene status of 8-10 years old government school children of Udaipur city, India. Materials and Methods A total of nine school teachers and 279, 8-10 year old school children from two government schools were included in the study. The questionnaire on oral health knowledge and practice contained 17 questions to evaluate the knowledge and practice of children towards oral hygiene before and after the teachers training program. Baseline and six months post training data on oral health knowledge and practice was obtained by the questionnaire method. Baseline and six months post training data on oral hygiene status was obtained by OHI-S Index. Statistical analysis was done using software SPSS 22, the test used were McNemar’s test, paired t-test. Results Pre and post training data were compared and it was found that there was a significant improvement in oral health knowledge and practices of school teachers and children. Also oral hygiene status of school children was significantly improved after the program. Conclusion Results of the present study suggest that experiential learning is an effective school based oral health education method for improvement of oral hygiene in primary school children. PMID:27656573

  12. A Longitudinal Examination of 10-year Change in Vocational and Educational Activities for Adults with Autism Spectrum Disorders

    PubMed Central

    Taylor, Julie Lounds; Center, Vanderbilt Kennedy; Mailick, Marsha R.

    2014-01-01

    The transition from adolescence to adulthood has been shown to be a time of amplified risk for individuals with autism spectrum disorders (ASD). It is unknown, however, whether problems in educational attainment and employment in the years after high school exit represent “momentary perturbations” in development or a “turning point” with long-lasting effects throughout adulthood. The present study addressed this question by examining 10-year trajectories of vocational and educational activities for adults with ASD, as well as the personal characteristics and environmental resources that predicted these activities. Participants were 161 adults with ASD (ages 18-52 at the start of the study, M=30.9 years) who were part of a larger longitudinal study. Data were collected at 6 time points over a 10-year period. Results indicated significant declines in the level of independence and engagement in vocational/educational activities over the study period, particularly for women. Greater independence in vocational activities was found for those with more independence in activities of daily living. Net of personal characteristics, receipt of more services was marginally related to greater improvement in vocational independence. PMID:24001150

  13. A longitudinal examination of 10-year change in vocational and educational activities for adults with autism spectrum disorders.

    PubMed

    Taylor, Julie Lounds; Mailick, Marsha R

    2014-03-01

    The transition from adolescence to adulthood has been shown to be a time of amplified risk for individuals with autism spectrum disorders (ASD). It is unknown, however, whether problems in educational attainment and employment in the years after high school exit represent momentary perturbations in development or a turning point with long-lasting effects throughout adulthood. The present study addressed this question by examining 10-year trajectories of vocational and educational activities for adults with ASD, as well as the personal characteristics and environmental resources that predicted these activities. Participants were 161 adults with ASD (ages 18-52 years at the start of the study; M = 30.9) who were part of a larger longitudinal study. Data were collected at 6 time points over a 10-year period. Results indicated significant declines in the level of independence and engagement in vocational/educational activities over the study period, particularly for women. Greater independence in vocational activities was found for those with more independence in activities of daily living. After controlling for personal characteristics, receipt of more services was marginally related to greater improvement in vocational independence.

  14. A Randomized Trial Comparing Part-time Patching with Observation for Children 3–10 Years Old with Intermittent Exotropia

    PubMed Central

    Cotter, Susan A.; Mohney, Brian G.; Chandler, Danielle L.; Holmes, Jonathan M.; Repka, Michael X.; Melia, Michele; Wallace, David K.; Beck, Roy W.; Birch, Eileen E.; Kraker, Raymond T.; Tamkins, Susanna M.; Miller, Aaron M.; Sala, Nicholas A.; Glaser, Stephen R.

    2014-01-01

    over a 6-month period is uncommon with or without patching treatment. Although there is a slightly lower deterioration rate with patching, both management approaches are reasonable for treating 3 to 10 year olds with IXT. PMID:25234012

  15. Predicting 10-Year Risk of Fatal Cardiovascular Disease in Germany: An Update Based on the SCORE-Deutschland Risk Charts

    PubMed Central

    Rücker, Viktoria; Keil, Ulrich; Fitzgerald, Anthony P; Malzahn, Uwe; Prugger, Christof; Ertl, Georg; Heuschmann, Peter U; Neuhauser, Hannelore

    2016-01-01

    Estimation of absolute risk of cardiovascular disease (CVD), preferably with population-specific risk charts, has become a cornerstone of CVD primary prevention. Regular recalibration of risk charts may be necessary due to decreasing CVD rates and CVD risk factor levels. The SCORE risk charts for fatal CVD risk assessment were first calibrated for Germany with 1998 risk factor level data and 1999 mortality statistics. We present an update of these risk charts based on the SCORE methodology including estimates of relative risks from SCORE, risk factor levels from the German Health Interview and Examination Survey for Adults 2008–11 (DEGS1) and official mortality statistics from 2012. Competing risks methods were applied and estimates were independently validated. Updated risk charts were calculated based on cholesterol, smoking, systolic blood pressure risk factor levels, sex and 5-year age-groups. The absolute 10-year risk estimates of fatal CVD were lower according to the updated risk charts compared to the first calibration for Germany. In a nationwide sample of 3062 adults aged 40–65 years free of major CVD from DEGS1, the mean 10-year risk of fatal CVD estimated by the updated charts was lower by 29% and the estimated proportion of high risk people (10-year risk > = 5%) by 50% compared to the older risk charts. This recalibration shows a need for regular updates of risk charts according to changes in mortality and risk factor levels in order to sustain the identification of people with a high CVD risk. PMID:27612145

  16. Predicting 10-Year Risk of Fatal Cardiovascular Disease in Germany: An Update Based on the SCORE-Deutschland Risk Charts.

    PubMed

    Rücker, Viktoria; Keil, Ulrich; Fitzgerald, Anthony P; Malzahn, Uwe; Prugger, Christof; Ertl, Georg; Heuschmann, Peter U; Neuhauser, Hannelore

    2016-01-01

    Estimation of absolute risk of cardiovascular disease (CVD), preferably with population-specific risk charts, has become a cornerstone of CVD primary prevention. Regular recalibration of risk charts may be necessary due to decreasing CVD rates and CVD risk factor levels. The SCORE risk charts for fatal CVD risk assessment were first calibrated for Germany with 1998 risk factor level data and 1999 mortality statistics. We present an update of these risk charts based on the SCORE methodology including estimates of relative risks from SCORE, risk factor levels from the German Health Interview and Examination Survey for Adults 2008-11 (DEGS1) and official mortality statistics from 2012. Competing risks methods were applied and estimates were independently validated. Updated risk charts were calculated based on cholesterol, smoking, systolic blood pressure risk factor levels, sex and 5-year age-groups. The absolute 10-year risk estimates of fatal CVD were lower according to the updated risk charts compared to the first calibration for Germany. In a nationwide sample of 3062 adults aged 40-65 years free of major CVD from DEGS1, the mean 10-year risk of fatal CVD estimated by the updated charts was lower by 29% and the estimated proportion of high risk people (10-year risk > = 5%) by 50% compared to the older risk charts. This recalibration shows a need for regular updates of risk charts according to changes in mortality and risk factor levels in order to sustain the identification of people with a high CVD risk. PMID:27612145

  17. Vaccine-associated measles in the low-incidence country of Korea over a 10-year period.

    PubMed

    Choe, Young June; Eom, Hye Suk; Bae, Geun-Ryang

    2014-01-01

    As the incidence of measles decreases, cases reported as suspected measles will increasingly involve rash associated with measles vaccination itself. In this study, we assessed vaccine-associated measles cases reported in Korea between 2002 and 2012 using a standardized assessment and following by the World Health Organization case definition criteria. We retrospectively analyzed data regarding (i) wild-type measles and (ii) vaccine-associated measles in patients aged 12-23 months. The presence or absence of fever, rash, cough, coryza, conjunctivitis, and Koplik spots were reviewed. Males were more likely to be reported with vaccine-associated measles than with wild-type measles (68% vs. 47%, P < 0.05). The number of patients with wild-type measles peaked between April and July, whereas that of patients with vaccine-associated measles remained relatively constant throughout the year. However, after excluding the cases reported during the 2007 outbreak in Korea, the trend was similar between the two groups. Cough, coryza, and conjunctivitis were more likely to be present in patients with wild-type measles (32-61% vs. 10-43%, P < 0.05); conversely, the absence of these symptoms was noted in most patients with vaccine-associated measles. We therefore conclude that cough, coryza, and conjunctivitis may be useful as key positive findings to distinguish between wild-type measles and vaccine-associated measles infection among 12-23-month-old patients in a country with a low incidence of measles. PMID:24858606

  18. Living in danger: previous violence, socioeconomic position, and mortality risk among women over a 10-year period.

    PubMed

    Trygged, Sven; Hedlund, Ebba; Kåreholt, Ingemar

    2014-01-01

    Violence against women has many negative consequences. In this short report the authors investigate patterns of mortality among women experiencing violence leading to inpatient care from 1992 to 2006. Do women who are victims of severe violence have an increased mortality risk (a) in general? (b) by violence? (c) by suicide? Does socioeconomic position have any bearing on the mortality risk? The study was based on Swedish national registers, where 6,085 women exposed to violence resulting in inpatient care were compared with a nonexposed population sample of 55,016 women. Women of all social strata previously exposed to severe violence and treated in hospital had a highly increased risk of premature death from all-cause mortality, violence, or suicide. Women previously exposed to severe violence continue to live a life in danger. There is need for a societal response to support and protect these women against further violence after discharge from hospital.

  19. Visual plus nonvisual hallucinations in Parkinson's disease: development and evolution over 10 years.

    PubMed

    Goetz, Christopher G; Stebbins, Glenn T; Ouyang, Bichun

    2011-10-01

    The objective of the study was to assess the development and evolution of visual and nonvisual hallucinations in patients with Parkinson's disease over 10 years. Hallucinations increase over time, but minimal attention has been placed on nonvisual domains. We studied 60 patients with Parkinson's disease who had never hallucinated at baseline and followed them over 10 years. The Rush Hallucination Inventory monitored frequency and type (visual, auditory, tactile, olfactory) of hallucinations at baseline and after 0.5, 1.5, 4, 6, and 10 years. Descriptive statistics were applied, and general estimating equation modeling assessed longitudinal risks. Over 10 years, visual hallucinations were endorsed by patients more frequently than other sensory modalities. Whereas isolated visual hallucinations dominated the early hallucination profile, visual plus nonvisual hallucinations accounted for progressively higher proportions of hallucinators over 10 years: 0.5 years, 0%; 4 years, 26%; 6 years, 47%; 10 years, 60% (odds ratio, 1.17; confidence interval, 1.01-1.37; P = .04). Once visual plus nonvisual hallucinations developed, the risk of continuing to have multidomain hallucinations was high (odds ratio, 3.67; confidence interval, 1.13-11.93; P = .03). Hallucination severity was highly associated with current visual plus nonvisual hallucinations (odds ratio, 4.06; confidence interval, 2.93-5.61; P < .0001) and the continuation of multidomain hallucinations (odds ratio, 1.58; confidence interval, 1.12-2.24; P = .01). Whereas visual hallucinations in isolation are classic in Parkinson's disease, nonvisual hallucinations emerge over time, and the combination of visual with nonvisual hallucinations predominates in late Parkinson's disease. To capture the breadth and severity of hallucinations in chronically hallucinating patients with Parkinson's disease, screening inventories and practice-based interviews must include questions on both visual and nonvisual components.

  20. Linear-scaling explicitly correlated treatment of solids: Periodic local MP2-F12 method

    SciTech Connect

    Usvyat, Denis

    2013-11-21

    Theory and implementation of the periodic local MP2-F12 method in the 3*A fixed-amplitude ansatz is presented. The method is formulated in the direct space, employing local representation for the occupied, virtual, and auxiliary orbitals in the form of Wannier functions (WFs), projected atomic orbitals (PAOs), and atom-centered Gaussian-type orbitals, respectively. Local approximations are introduced, restricting the list of the explicitly correlated pairs, as well as occupied, virtual, and auxiliary spaces in the strong orthogonality projector to the pair-specific domains on the basis of spatial proximity of respective orbitals. The 4-index two-electron integrals appearing in the formalism are approximated via the direct-space density fitting technique. In this procedure, the fitting orbital spaces are also restricted to local fit-domains surrounding the fitted densities. The formulation of the method and its implementation exploits the translational symmetry and the site-group symmetries of the WFs. Test calculations are performed on LiH crystal. The results show that the periodic LMP2-F12 method substantially accelerates basis set convergence of the total correlation energy, and even more so the correlation energy differences. The resulting energies are quite insensitive to the resolution-of-the-identity domain sizes and the quality of the auxiliary basis sets. The convergence with the orbital domain size is somewhat slower, but still acceptable. Moreover, inclusion of slightly more diffuse functions, than those usually used in the periodic calculations, improves the convergence of the LMP2-F12 correlation energy with respect to both the size of the PAO-domains and the quality of the orbital basis set. At the same time, the essentially diffuse atomic orbitals from standard molecular basis sets, commonly utilized in molecular MP2-F12 calculations, but problematic in the periodic context, are not necessary for LMP2-F12 treatment of crystals.

  1. Unification of some biochemical methods of research in the pre- and post-flight periods

    NASA Technical Reports Server (NTRS)

    Tigranyan, R. A.

    1980-01-01

    The biochemical methods for determination of various parameters and factors during pre- and post-flight periods, as used by American and Soviet teams dealing with space flight medicine are compared. The emphasis is on the exchange of information on the study of the blood and urine content of space travelers before and after space flight. A series of electrolytic, enzymatic, and hormonal factors is discussed.

  2. Predictors of temporal patterns of psychiatric distress during 10 years following the nuclear accident at Three Mile Island.

    PubMed

    Dew, M A; Bromet, E J

    1993-04-01

    The present study examines psychiatric symptom levels during a 10-year period in a community sample of mothers of young children. All were identified in the early aftermath of the 1979 Three Mile Island nuclear accident, and followed through the accident's 1989 anniversary. Cluster analysis was used to identify long-term distress profiles during the study period; women's temporal profiles were found to be either (a) stable and at low, clinically nonsignificant levels of distress across all measurement points or (b) at consistently elevated, clinically significant levels that varied with the timing of postaccident events such as the restart of the undamaged reactor and the 10th anniversary. Subsequent multivariate analyses indicated that preaccident characteristics, as well as parameters reflecting respondents' initial involvement with, and reactions to the accident, were important for distinguishing between women within the two temporal profile groups. Implications of the results for both policy formulation and continued research on significant environmental stressors is discussed. PMID:8511662

  3. Evaluation of selected methods for determining streamflow during periods of ice effect

    USGS Publications Warehouse

    Melcher, Norwood B.; Walker, J.F.

    1992-01-01

    Seventeen methods for estimating ice-affected streamflow are evaluated for potential use with the U.S. Geological Survey streamflow-gaging station network. The methods evaluated were identified by written responses from U.S. Geological Survey field offices and by a comprehensive literature search. The methods selected and techniques used for applying the methods are described in this report. The methods are evaluated by comparing estimated results with data collected at three streamflow-gaging stations in Iowa during the winter of 1987-88. Discharge measurements were obtained at 1- to 5-day intervals during the ice-affected periods at the three stations to define an accurate baseline record. Discharge records were compiled for each method based on data available, assuming a 6-week field schedule. The methods are classified into two general categories-subjective and analytical--depending on whether individual judgment is necessary for method application. On the basis of results of the evaluation for the three Iowa stations, two of the subjective methods (discharge ratio and hydrographic-and-climatic comparison) were more accurate than the other subjective methods and approximately as accurate as the best analytical method. Three of the analytical methods (index velocity, adjusted rating curve, and uniform flow) could potentially be used at streamflow-gaging stations, where the need for accurate ice-affected discharge estimates justifies the expense of collecting additional field data. One analytical method (ice-adjustment factor) may be appropriate for use at stations with extremely stable stage-discharge ratings and measuring sections. Further research is needed to refine the analytical methods. The discharge-ratio and multiple-regression methods produce estimates of streamflow for varying ice conditions using information obtained from the existing U.S. Geological Survey streamflow-gaging network.

  4. Pattern of Venous Thromboembolism Occurrence in Gynecologic Malignancy: Incidence, Timing, and Distribution a 10-Year Retrospective Single-institutional Study

    PubMed Central

    Ye, Shuang; Zhang, Wei; Yang, Jiaxin; Cao, Dongyan; Huang, Huifang; Wu, Ming; Lang, Jinghe; Shen, Keng

    2015-01-01

    Abstract The aim of this single-institutional 10-year retrospective study was to investigate the clinical pattern (incidence, type, timing, and location) of venous thromboembolism (VTE) in Chinese patients with gynecologic cancer. Cases were identified by searching institutional Electronic Discharge Database. A comprehensive review of medical documentation was then performed to collect relevant data. The detection of VTE was symptom-triggered. A total of 155 VTE events were identified out of 7562 cases over the past 10-year period in our hospital. The incidence of clinically significant VTE was 2.0% in gynecologic malignancy, with vulvar cancer (3.7%) and ovarian cancer (2.5%) being the high-risk types (P = 0.01, Chi-square test). Perioperative period (35.1%) and preoperation (29.1%) were the 2 incidence peaks. Seventeen cases of pulmonary embolism (PE) occurred prior to surgery. Ovarian cancer patients were more likely to present preoperative PE compared to other site of cancer (76.4%; P = 0.01, Chi-square test). More preoperative VTE cases were complicated by PE than those in the perioperative period (39.5% vs 17.3%, P = 0.02, Chi-square test). Bilateral lower extremity deep vein thrombosis (DVT) accounted for 32.6% and there existed a preponderance of left-sided DVT (47.5% vs 17.0%, ratio 2.79:1). Femoral vein (36.6%) was the most common location for DVT. About 2.0% of the Chinese patients with gynecologic carcinoma developed clinical VTE, mostly during perioperative period and the time of diagnosis. The true incidence might have been under-estimated due to several reasons. The need for increased patient education and awareness of VTE is of importance. PMID:26683971

  5. Cost savings associated with 10 years of road safety policies in Catalonia, Spain

    PubMed Central

    Suelves, Josep M; Barbería, Eneko

    2013-01-01

    Abstract Objective To determine whether the road safety policies introduced between 2000 and 2010 in Catalonia, Spain, which aimed primarily to reduce deaths from road traffic collisions by 50% by 2010, were associated with economic benefits to society. Methods A cost analysis was performed from a societal perspective with a 10-year time horizon. It considered the costs of: hospital admissions; ambulance transport; autopsies; specialized health care; police, firefighter and roadside assistance; adapting to disability; and productivity lost due to institutionalization, death or sick leave of the injured or their caregivers; as well as material and administrative costs. Data were obtained from a Catalan hospital registry, the Catalan Traffic Service information system, insurance companies and other sources. All costs were calculated in euros (€) at 2011 values. Findings A substantial reduction in deaths from road traffic collisions was observed between 2000 and 2010. Between 2001 and 2010, with the implementation of new road safety policies, there were 26 063 fewer road traffic collisions with victims than expected, 2909 fewer deaths (57%) and 25 444 fewer hospitalizations. The estimated total cost savings were around €18 000 million. Of these, around 97% resulted from reductions in lost productivity. Of the remaining cost savings, 63% were associated with specialized health care, 15% with adapting to disability and 8.1% with hospital care. Conclusion The road safety policies implemented in Catalonia in recent years were associated with a reduction in the number of deaths and injuries from traffic collisions and with substantial economic benefits to society. PMID:23397348

  6. Decreases in human immunodeficiency virus infection rates in Kombolcha, Ethiopia: a 10-year data review

    PubMed Central

    Shiferaw, Melashu Balew; Gebregergs, Gebremedhin Berhe; Sinishaw, Mulusew Alemneh; Yesuf, Yohannes Amede

    2016-01-01

    Introduction Acquired immunodeficiency syndrome is one of the most serious public health and development challenges in sub-Saharan Africa, including Ethiopia. A particular challenge for prevention strategies has been the emergence of hotspot areas. Therefore, human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome programs should not be based on national level statistics, but need to be more focused geographically. Kombolcha is one of the high spot areas with different projects and development corridors. Hence, the aim of this study is to assess the trend of HIV infection rates among patients who visited Africa Service Committee clinic from 2005 to 2014. Methods An institutional-based cross-sectional study was conducted from January 1 to January 30, 2016. All records of new patients enrolled from February 8, 2005 to December 31, 2014 were reviewed. Data on sociodemographic information, risky sexual behavior, and HIV test result were collected from each study participant using data collection format. Data were analyzed using SPSS version 20.0. A multivariate logistic regression model was used to identify risk factors of HIV infection. Results The overall HIV infection was 10.8% (2,233/20,674). The rate of infection varied from 13.3% in 2005 to 4.5% in 2014, and its trend had significantly declined from 2008 to 2014. Urban residence (adjusted odds ratio [AOR]: 2.53; 95% confidence interval [CI]: 1.22–5.25), patients who ever had intercourse with penetration (AOR: 5.62; 95% CI: 1.11–28.57), and those who had marriage experience (AOR: 11.65; 95% CI: 4.2–32.3) were more infected with HIV. Conclusion The trend of HIV infection significantly reduced in the last 10 years in Kombolcha area. However, the HIV infection still remains high (4.5%) that needs intervention of those who had marriage experience, risky sexual behavior, and urban dwellers. PMID:27462177

  7. The 10-year Trend of Periprocedural Complication Following Carotid Artery Stenting; Single Center Experience

    SciTech Connect

    Hong, Jeong-Ho; Kang, Jihoon; Yeo, Min-Ju; Kim, Beom Joon; Jang, Min Uk; Bae, Hee-Joon; Kwon, O-Ki; Hwang, Gyo Jun; Oh, Chang Wan; Jung, Cheolkyu; Lee, Ji Sung; Han, Moon-Ku

    2015-04-15

    PurposeCarotid endarterectomy and stenting are used to treat carotid stenosis, with the volume of carotid artery procedures increasing over the past decade. We investigated the 10-year trend of periprocedural complications with an increasing procedure volume of carotid stenting at a single tertiary hospital.MethodsWe collected 416 consecutive cases (384 patients) of carotid artery stenting performed for either symptomatic (231 cases, 55.5 %) or asymptomatic (185 cases, 44.5 %) internal carotid artery stenosis at a single center. Periprocedural complication was defined as any stroke, myocardial infarction, or death. Procedure-related outcome included any dissection, hemodynamic event, or periprocedural complication.ResultsThe mean age was 68.8 years (82.8 % males; range of 20–89 years); 23.9 % were older than 75 years. Before the procedure, 99.3 and 56.0 % of patients received antiplatelet and lipid-lowering medication, respectively. The overall periprocedural complication rate was 3.6 % (1.6 and 5.2 % in the asymptomatic and symptomatic group, respectively). The composite outcome of any stroke or death was 3.4 %. Periprocedural complication and procedure-related outcome showed a decremental trend with increasing procedure volume, and this trend remained after adjusting for confounders.ConclusionsOur study suggests that carotid stenting at an experienced center might reduce the periprocedural complications. Our periprocedural complication rate of carotid artery stenting may be comparable to, or somewhat lower than, that reported in other clinical trials.

  8. Estrogen receptor testing and 10-year mortality from breast cancer: A model for determining testing strategy

    PubMed Central

    Naugler, Christopher

    2012-01-01

    Background: The use of adjuvant tamoxifen therapy in the treatment of estrogen receptor (ER) expressing breast carcinomas represents a major advance in personalized cancer treatment. Because there is no benefit (and indeed there is increased morbidity and mortality) associated with the use of tamoxifen therapy in ER-negative breast cancer, its use is restricted to women with ER expressing cancers. However, correctly classifying cancers as ER positive or negative has been challenging given the high reported false negative test rates for ER expression in surgical specimens. In this paper I model practice recommendations using published information from clinical trials to address the question of whether there is a false negative test rate above which it is more efficacious to forgo ER testing and instead treat all patients with tamoxifen regardless of ER test results. Methods: I used data from randomized clinical trials to model two different hypothetical treatment strategies: (1) the current strategy of treating only ER positive women with tamoxifen and (2) an alternative strategy where all women are treated with tamoxifen regardless of ER test results. The variables used in the model are literature-derived survival rates of the different combinations of ER positivity and treatment with tamoxifen, varying true ER positivity rates and varying false negative ER testing rates. The outcome variable was hypothetical 10-year survival. Results: The model predicted that there will be a range of true ER rates and false negative test rates above which it would be more efficacious to treat all women with breast cancer with tamoxifen and forgo ER testing. This situation occurred with high true positive ER rates and false negative ER test rates in the range of 20-30%. Conclusions: It is hoped that this model will provide an example of the potential importance of diagnostic error on clinical outcomes and furthermore will give an example of how the effect of that error could be

  9. The DOTS strategy in China: results and lessons after 10 years.

    PubMed Central

    Xianyi, Chen; Fengzeng, Zhao; Hongjin, Duanmu; Liya, Wan; Lixia, Wang; Xin, Du; Chin, Daniel P.

    2002-01-01

    OBJECTIVE: To analyse the five-point tuberculosis (TB) strategy, DOTS, 10 years after its implementation in one-half of China's population, and to suggest lessons for future implementation of the DOTS strategy. METHODS: We analysed trends in case-finding and treatment outcome over time following implementation of the DOTS strategy in each county, using routine reporting data from the Infectious and Endemic Disease Control (IEDC) project (1991 - 2000). We also determined the proportion of counties with different levels of case-finding for the fifth and sixth years of DOTS implementation. FINDINGS: From 1991 to 1995, DOTS expanded rapidly to cover more than 90% of target population and counties. By 2000, 8 million TB suspects had received free diagnostic evaluation: 1.8 million TB cases were diagnosed, free treatment was provided to 1.3 million smear-positive cases, and more than 90% were cured. During DOTS implementation, the percentage of previously treated cases decreased among all smear-positive cases and treatment outcomes improved. Despite these achievements, the detection rate for new smear-positive cases in the project was estimated to be only 54% in 1998, and 41.2% of the counties had a below average or low level of case-finding (with substantial variation between provinces). CONCLUSIONS: The IEDC project demonstrated that it is feasible to rapidly expand DOTS on a large scale. The global target of an 85% cure rate was quickly achieved, and the level of drug-resistance was probably reduced by this project. However, case-detection did not reach the 70% global target, and more research is needed on how to enhance this. PMID:12131998

  10. Improvement of the periodate-borohydride surface-labeling method for human blood platelets

    SciTech Connect

    Steiner, B.; Clemetson, K.J.; Luescher, E.F.

    1983-01-01

    The periodate/sodium boro(/sup 3/H)hydride ((/sup 3/H)-NaBH4) method is extensively used for the specific labeling of cell surface glycoproteins. Reduction with tritiated borohydride is also used in other surface-labeling techniques, the neuraminidase/galactose oxidase/(/sup 3/H)-NaBH4 method (specific for terminal galactose and N-acetyl-galactosamine residues) and the pyridoxal phosphate/(/sup 3/H)-NaBH4 method (specific for protein). By modification of the reaction conditions during the periodate-oxidation and borohydride-reduction, the ratio of the incorporated to the total added radioactivity could be increased by a factor of 50, while the specific activity of the labeled material was twice as high as in the original method. Alternatively, by another modification, the specific activity of the labeled material could be increased about 10-fold. The influence of the most important parameters was investigated in detail. Sodium dodecyl sulfate gel electrophoresis and fluorography demonstrate that the labeling pattern of the membrane glycoproteins is the same as with the conventional method.

  11. Perturbation method for the floquet eigenvalues and stability boundary of periodic linear systems

    NASA Astrophysics Data System (ADS)

    Wu, W.-T.; Griffin, J. H.; Wickert, J. A.

    1995-04-01

    A multiple parameter perturbation method is developed to determine the Floquet eigenvalues and stability boundary of a linear discrete system that is described by a system of ordinary differential equations with periodic coefficients. In the method, the state of the system is determined by solving a number of decoupled problems and, as a result, implementation of the method is computationally efficient even when the dimension of the system is large. The method is first applied to Mathieu's equation in order to illustrate its application to a relatively straightforward, standard problem. It is then applied to the torsional analysis of a boat's drive train to show application to a large scale system of some practical importance.

  12. [Tumors of the adipose tissue during 10 years of diagnostic activities (1979-1988)].

    PubMed

    Grandi, E; Trisolini, M P

    1990-01-01

    Adipose tissue tumors in ten years of diagnostic activity (1979-1988). We have reconsidered our material on tumors of adipose tissue, which were observed for 10 years, from 1979 to 1988, at Istituto di Anatomia Patologica dell'Università degli Studi - Arcispedale S. Anna di Ferrara. The whole collection consists of 772 tumors, 742 lipomas and 30 liposarcomas. We have intended to examine the development of our diagnostic experience through time and compare our data with those of literature. Simple lipomas and fibrolipomas are the most common histological types (78.8%), followed by angiolipomas (3.6%) and intramuscular lipomas (2.5%). The other types have a lower percentage. In every cases the morphologic and clinicopathologic features are shown, as well as compared with those of literature, and discordances that may result are interpreted. We are firmly convinced that routine diagnosis is not always compatible with rigid classifications and that it is not easy to use morphologic criteria which vary in quality and quantity. We have consequently aimed at reducing any possible distortion in diagnosis due to subjectivity, by sticking rigorously to consolidated morphology. Although our findings mostly agree with those of literature, some discordances still exist; the most significant of them regard age incidence. Among spindle cell lipomas there are two cases diagnosed in early childhood; the number of angiolipomas as well seems to be very high in this period of life. Particularly important from the clinical point of view has been the decision of diagnosing a thigh tumor as lipoblastoma in an eighteen-year-old boy. Other discordances seem to us less significant, as, for example, the absence of intramuscular lipomas in the thigh, which is to be considered, in our opinion, a chance event that we could not explain otherwise. Liposarcomas represent the 4% of the cases. Only one cases has been diagnosed in a patient less than 40 years old. The location sites agree with those

  13. Is flow cytometric evaluation of DNA degradation a reliable method to investigate the early postmortem period?

    PubMed

    Di Nunno, N R; Costantinides, F; Bernasconi, P; Bottin, C; Melato, M

    1998-03-01

    The time of death can be established by determining the length of the postmortem interval. Many methods have been proposed to achieve this goal. Flow cytometric evaluation of DNA degradation seems to be reliable for the first 72 hours after death. Our study evaluated the correspondence of the corruption process between in vitro and corpse tissues. We chose spleen tissue to perform our investigation because it is rich in nucleated cells. Results showed a precise correspondence between the two kinds of samples in the time period between 24 and 36 hours. The period from 36 to 72 hours is characterized by a much looser correspondence than that found in the first period. After the first 72 hours, DNA denaturation is massive and does not allow useful cytofluorimetric readings. The spleen does not seem to be the most suitable organ for this type of investigation because it tends to colliquate very rapidly. We therefore are evaluating other organs to identify a more suitable tissue source for the investigation of longer postmortem period using flow cytometry.

  14. Seal, replacement or monitoring amalgam restorations with occlusal marginal defects? Results of a 10-year clinical trial.

    PubMed

    Moncada, G; Fernández, E; Mena, K; Martin, J; Vildósola, P; De Oliveira Junior, O B; Estay, J; Mjör, I A; Gordan, V V

    2015-11-01

    The aim of this prospective and blind clinical trial was to assess the effectiveness of sealing localized marginal defects of amalgam restoration that were initially scheduled to be replaced. A cohort of twenty six patients with 60 amalgam restorations (n=44Class I and n=16Class II), that presented marginal defects deviating from ideal (Bravo) according to USPHS criteria, were assigned to either sealing or replacement groups: A: sealing n=20, Replacement n=20, and no treatment (n=20). Two blind examiners evaluated the restorations at baseline (K=0.74) and after ten years (K=0.84) according with USPHS criteria, in four parameters: marginal adaptation (MA), secondary caries (SC), marginal staining (MS) and teeth sensitivity (TS). Multiple comparison of restorations degradation/upgrade was analyzed by Friedman test and the comparisons within groups were performed by Wilcoxon test. After 10 years, 44 restorations were assessed (73.3%), Group A: n=14 and Group B: n=16; and Group C: n=14 sealing and replacement amalgam restorations presented similar level of quality in MA (p=0.76), SC (p=0.25) and TS (p=0.52), while in MS (p=0.007) presented better performance in replacement group after 10-years. Most of the occlusal amalgam restorations with marginal gaps showed similar long term outcomes than the restorations were sealed, replaced, or not treated over a 10-year period. Most of the restorations of the three groups were clinically acceptable, under the studied parameters. All restorations had the tendency to present downgrade/deterioration over time. PMID:26231302

  15. Analysis of all-optically tunable functionalities in subwavelength periodic structures by the Fourier modal method

    NASA Astrophysics Data System (ADS)

    Bej, Subhajit; Tervo, Jani; Francés, Jorge; Svirko, Yuri P.; Turunen, Jari

    2016-05-01

    We propose the nonlinear Fourier Modal Method (FMM) [J. Opt. Soc. Am. B 31, 2371 (2014)] as a convenient and versatile numerical tool for the design and analysis of grating based next generation all-optical devices. Here, we include several numerical examples where the FMM is used to simulate all-optically tunable functionalities in sub-wavelength periodic structures. At first, we numerically investigate a 1-D periodic nonlinear binary grating with amorphous TiO2. We plot the diffraction efficiency in the transmitted orders against the structure depth for normally incident plane wave. Change in diffraction efficiencies for different incident field amplitudes are evident from the plots. We verify the accuracy of our implementation by comparing our results with the results obtained with the nonlinear Split Field-Finite Difference Time Domain (SF-FDTD) method. Next we repeat the same experiment with vertically standing amorphous Titanium dioxide (TiO2) nanowire arrays grown on top of quartz which are periodic in two mutually perpendicular directions and examine the efficiencies in the direct transmitted light for different incident field amplitudes. Our third example includes analysis of a form birefringent linear grating with Kerr medium. With FMM we demonstrate that the birefringence of such a structure can be tuned by all-optical means. As a final example, we design a narrow band Guided Mode Resonance Filter (GMRF). Numerical experiments based on the nonlinear FMM reveal that the spectral tunability of such a filter can be obtained by all-optical means.

  16. Early Predictors of Career Development: A 10-Year Follow-up Study

    ERIC Educational Resources Information Center

    Ferreira, Joaquim Armando; Santos, Eduardo J. R.; Fonseca, Antonio C.; Haase, Richard F.

    2007-01-01

    This paper presents empirical findings from a 10-year longitudinal study of the educational and occupational socialization of 445 participants who were about 7 years old when first tested, and about 17 years old at the fourth time of measurement. In addition to collecting psychological measurements from the participants, behavioral reports were…

  17. A Content Analysis of 10 Years of Clinical Supervision Articles in Counseling

    ERIC Educational Resources Information Center

    Bernard, Janine M.; Luke, Melissa

    2015-01-01

    This content analysis follows Borders's (2005) review of counseling supervision literature and includes 184 counselor supervision articles published over the past 10 years. Articles were coded as representing 1 of 3 research types or 1 of 3 conceptual types. Articles were then analyzed for main topics producing 11 topic categories.

  18. Educational Attainment of 10-Year-Old Children with Treated and Untreated Visual Defects.

    ERIC Educational Resources Information Center

    Stewart-Brown, Sarah; And Others

    1985-01-01

    Children with visual impairments who participated in a 10-year survey were compared with peers on measures of intelligence, reading, mathematics, and sporting ability. Results are consistent with earlier findings of increased intelligence among Ss with myopia and slightly reduced intelligence among Ss with amblyopia. It was concluded that the…

  19. Personnel Needs in School Psychology: A 10-Year Follow-Up Study on Predicted Personnel Shortages

    ERIC Educational Resources Information Center

    Castillo, Jose M.; Curtis, Michael J.; Tan, Sim Yin

    2014-01-01

    Concerns regarding whether a sufficient supply of school psychologists exists have been evident for decades. Studies have predicted that school psychology would face a critical personnel shortage that would peak in 2010, but continue into the foreseeable future. The current study is a 10-year follow-up investigation based on previously published…

  20. Bullying and Attention-Deficit-Hyperactivity Disorder in 10-Year-Olds in a Swedish Community

    ERIC Educational Resources Information Center

    Holmberg, Kirsten; Hjern, Anders

    2008-01-01

    The association of attention-deficit-hyperactivity disorder (ADHD) with bullying in the peer group in school was studied in an entire population of 577 fourth graders (10-year-olds) in one municipality in Stockholm, Sweden. The schoolchildren were screened for ADHD in a two-step procedure that included Conners' ratings of behavioural problems:…

  1. Childhood Peer Reputation as a Predictor of Competence and Symptoms 10 Years Later

    ERIC Educational Resources Information Center

    Gest, Scott D.; Sesma, Arturo, Jr.; Masten, Ann S.; Tellegen, Auke

    2006-01-01

    This study examined the differential developmental significance of multiple domains of peer reputation in childhood for current and future competence and symptoms. Participants were 205 children from a normative school cohort who completed assessments in grades 3-6 and then again 10 years later. Through re-analysis of original data from the…

  2. Getting an Early Start: Communication about Sexuality among Mothers and Children 6-10 Years Old

    ERIC Educational Resources Information Center

    Pluhar, Erika; Jennings, Tanya; DiIorio, Colleen

    2006-01-01

    Little information exists on communication about sexuality between parents and preadolescent children. This study collected qualitative data on family sexuality communication from 3 focus groups conducted with African American mothers of 6-10 year old children. Two broad themes emerged from the data: "Beyond the Birds and the Bees" and "Let's Talk…

  3. Psychosocial Family Treatment for a 10-Year-Old with Schizoaffective Disorder

    ERIC Educational Resources Information Center

    Klaus, Nicole M.; Fristad, Mary A.; Malkin, Catherine; Mackinaw-Koons, Barbara

    2008-01-01

    Schizophrenia spectrum disorders are rare in childhood and little is known about their psychosocial treatment. Relevant findings from the adult and child literature are reviewed. The case of 10-year-old "Michael" is presented, who participated in a randomized clinical trial of a psychoeducational family treatment for mood disorders. Following…

  4. Case Report: Homicide by a 10-Year-Old Girl with Autistic Disorder

    ERIC Educational Resources Information Center

    Mukaddes, Nahit Motavalli; Topcu, Zerrin

    2006-01-01

    This case study presents a 10-year-old girl with a diagnosis of Autistic Disorder, who killed her 6-month-old sister by throwing her out of a window. Her aggressive-impulsive behavior had a persistent pattern. She had a history of epilepsy, and was frequently exposed to physical abuse. She never attended a structured treatment program. Here, we…

  5. Frontal Electroencephalogram Activation Asymmetry, Emotional Intelligence, and Externalizing Behaviors in 10-Year-Old Children

    ERIC Educational Resources Information Center

    Santesso, L. Diane; Dana, L. Reker; Schmidt, Louis A.; Segalowitz, Sidney J.

    2006-01-01

    The purpose of the present study was to examine the relations among resting frontal brain electrical activity (EEG) (hypothesized to reflect a predisposition to positive versus negative affect and ability to regulate emotions), emotional intelligence, and externalizing behaviors in a sample of non-clinical 10-year-old children. We found that boys…

  6. Computer Card Games in Computer Science Education: A 10-Year Review

    ERIC Educational Resources Information Center

    Kordaki, Maria; Gousiou, Anthi

    2016-01-01

    This paper presents a 10-year review study that focuses on the investigation of the use of computer card games (CCGs) as learning tools in Computer Science (CS) Education. Specific search terms keyed into 10 large scientific electronic databases identified 24 papers referring to the use of CCGs for the learning of CS matters during the last…

  7. Impact of Adolescent Alcohol and Drug Use on Neuropsychological Functioning in Young Adulthood: 10-Year Outcomes

    ERIC Educational Resources Information Center

    Hanson, Karen L.; Medina, Krista Lisdahl; Padula, Claudia B.; Tapert, Susan F.; Brown, Sandra A.

    2011-01-01

    Because of ongoing neuromaturation, youth with chronic alcohol/substance use disorders (AUD/SUD) are at risk for cognitive decrements during young adulthood. We prospectively examined cognition over 10 years based on AUD/SUD history. Youth (N = 51) with no AUD/SUD history (n = 14), persisting AUD/SUD (n = 18), or remitted AUD/SUD (n = 19) were…

  8. Maintenance of Response Suppression Following Overcorrection: A 10-Year Retrospective Examination of Eight Cases.

    ERIC Educational Resources Information Center

    Foxx, Richard M.; Livesay, Jim

    1984-01-01

    A retrospective analysis of the progress of eight institutionalized subjects who had been successfully treated in overcorrection procedures 10 years earlier revealed that maladaptive behaviors of the highest functioning individuals showed the longest term and best suppression, and that staff tend to return to the status quo after the expert…

  9. Physical Activity Patterns During School Recess: A Study in Children 6 to 10 Years Old

    ERIC Educational Resources Information Center

    Lopes, Victor; Vasques, Catarina Margarida Silva; de Oliveira Pereira, Maria Beatriz Ferreira Leite

    2006-01-01

    The aims of this study were to characterize the spontaneous physical activity of children during school recess, and to estimate variation in physical activity associated with gender and age. A MTI actigraph (Model 7164) was used with a sample of 140 boys and 131 girls, 6 to 10 years of age. MTI counts were converted to METs using a regression…

  10. Public School Voice Clinics, Part II: Diagnosis and Recommendations--A 10-Year Review.

    ERIC Educational Resources Information Center

    Miller, Sandra Q.; Madison, Charles L.

    1984-01-01

    In 10 years of school district voice clinics, 249 cases were reviewed. Vocal nodules, chronic laryngitis and thickened cords were frequently noted. One-third of the cases had concomitant allergies, ear, and/or upper respiratory problems. Direct voice therapy was recommended for 65 percent of attendees. (Author/CL)

  11. Colon perforation during percutaneous renal surgery: a 10-year experience in a single endourology centre.

    PubMed

    Kachrilas, Stefanos; Stefanos, Kachrilas; Papatsoris, Athanasios; Athanasios, Papatsoris; Bach, Christian; Christian, Bach; Kontos, Stylianos; Stylianos, Kontos; Faruquz, Zaman; Zaman, Faruquz; Goyal, Anuj; Anuj, Goyal; Masood, Junaid; Junaid, Masood; Buchholz, Noor; Noor, Buchholz

    2012-06-01

    The use of percutaneous renal surgery has been recently revolutionised with novel endourological instruments and techniques. However, the incidence, prevention and management of severe complications such as colon perforation still lack consensus. By presenting our 10-year experience, we would like to highlight the diagnosis and management of the rare complication of colon perforation.

  12. Individual Oral Exams in Mathematics Courses: 10 Years of Experience at the Air Force Academy

    ERIC Educational Resources Information Center

    Boedigheimer, Ralph; Ghrist, Michelle; Peterson, Dale; Kallemyn, Benjamin

    2015-01-01

    Over the last 10 years faculty members in the Department of Mathematical Sciences at the United States Air Force Academy have incorporated individual oral exams into mathematics courses. We have experimented with various approaches, shared results and ideas with other department members, and refined our techniques. We have found that this…

  13. Re-Visited: A Tracer Study 10 Years Later--Detective Process

    ERIC Educational Resources Information Center

    Levin-Rozalis, Miry

    2004-01-01

    Does an early childhood program have an influence on its participants that is detectable 10 years later? The answer is "yes". This research managed to detect differences between children of Ethiopian origin who had immigrated to Israel. It also managed to generalize and conceptualize these differences and provide an explanation of them: The…

  14. Eastern Michigan University's Automated Storage and Retrieval System: 10 Years Later

    ERIC Educational Resources Information Center

    Bullard, Rita; Wrosch, Jackie

    2009-01-01

    Automated storage/retrieval systems (ASRSs) are playing an integral part in today's library operations and collections management. Eastern Michigan University installed an ASRS as part of the new Halle Library, which opened in May 1998, to provide "storage" for up to 800,000 items. Over the past 10 years our policies and procedures have been…

  15. Eating With Your Heart In Mind: 7 to 10 Year Olds.

    ERIC Educational Resources Information Center

    National Heart, Lung, and Blood Inst. (DHHS/NIH), Bethesda, MD.

    The purpose of this brightly illustrated guide is to teach 7-10 year old children that all healthy Americans, 2 years of age or older, should eat in a way that is low in saturated fat and cholesterol so as to help reduce the risk of heart disease. The theme reflected throughout the manual is that changes in eating patterns help lower blood…

  16. Self-Controlled Feedback in 10-Year-Old Children: Higher Feedback Frequencies Enhance Learning

    ERIC Educational Resources Information Center

    Chiviacowsky, Suzete; Wulf, Gabriele; de Medeiros, Franklin Laroque; Kaefer, Angelica; Wally, Raquel

    2008-01-01

    The purpose of the present study was to examine whether learning in 10-year-old children--that is, the age group for which the Chiviacowsky et al. (2006) study found benefits of self-controlled knowledge of results (KR)--would differ depending on the frequency of feedback they chose. The authors surmised that a relatively high feedback frequency…

  17. Learning Benefits of Self-Controlled Knowledge of Results in 10-Year-Old Children

    ERIC Educational Resources Information Center

    Chiviacowsky, Suzete; Wulf, Gabriele; Laroque de Medeiros, Franklin; Kaefer, Angelica; Tani, Go

    2008-01-01

    The purpose of the present study was to examine whether the learning benefits of self-controlled knowledge of results (KR) would generalize to children. Specifically, the authors chose 10-year-old children representative of late childhood. The authors used a task that required the children to toss beanbags at a target. One group received KR…

  18. If We Could Plan the Next 10 Years in Science Education...

    ERIC Educational Resources Information Center

    Mansell, Warwick

    2013-01-01

    Two major sessions at the 2013 ASE Summer Celebration Conference in Hatfield offered teachers (and other educators) the chance to debate and define the key issues facing science education over the next 10 years. Participants were asked to suggest the important issues. Then those with similar proposals were put into groups to develop the idea ready…

  19. Motor Performance and Dyslexia in a National Cohort of 10-Year-Old Children

    ERIC Educational Resources Information Center

    Haslum, M. N.; Miles, T. R.

    2007-01-01

    Data from the 10-year follow-up of the 1970 British Births Survey were examined for associations between motor performance and dyslexia. Five tests of motor performance were used: (a) balancing on one leg, (b) throwing a ball in the air, clapping and catching it, (c) walking backwards, (d) sorting matches and (e) graphaesthesia (recognizing shapes…

  20. Motor Skills in Children Aged 7-10 Years, Diagnosed with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Whyatt, Caroline P.; Craig, Cathy M.

    2012-01-01

    This study used the Movement Assessment Battery for Children (M-ABC2) to assess motor skills in children aged 7-10 years with autism (n = 18) in comparison to two groups of age-matched typically developing children; a receptive vocabulary matched group (n = 19) and a nonverbal IQ matched group (n = 22). The results supported previous work, as…

  1. Relationship between Motor Skill and Body Mass Index in 5- to 10-Year-Old Children

    ERIC Educational Resources Information Center

    D'Hondt, Eva; Deforche, Benedicte; De Bourdeaudhuij, Ilse; Lenoir, Matthieu

    2009-01-01

    The purpose of this study was to investigate gross and fine motor skill in overweight and obese children compared with normal-weight peers. According to international cut-off points for Body Mass Index (BMI) from Cole et al. (2000), all 117 participants (5-10 year) were classified as being normal-weight, overweight, or obese. Level of motor skill…

  2. Parent-Child Relations and Adolescent Self-Image Following Divorce: A 10-Year Study.

    ERIC Educational Resources Information Center

    Dunlop, Rosemary; Burns, Ailsa; Bermingham, Suzanne

    2001-01-01

    Explored links between self-image, family structure (divorced or intact), parent-child relations, and gender at 3 intervals over 10 years during adolescence to early adulthood. Results suggest a consistent relationship between high parental care, low overprotective control, and better self-image scores with a stronger effect among subjects from…

  3. Langerhans cell histiocytosis: recurrent lesions affecting mandible in a 10-year-old patient.

    PubMed

    Loducca, S V; Mantesso, A; Araújo, N S; Magalhães, M H

    2001-01-01

    Hand-Schuller-Christian disease is a multifocal variant of eosinophilic granuloma, characterised by the classical triad of bony lesions, exophthalmos and diabetes insipidus. This case relates recurrent Langerhans' cell histiocytosis lesions presented as destruction of periodontal support associated with diabetes in a 10-year-old patient. Medical history suggests that the case represents a case of Hand-Schuller Christian disease.

  4. Anticipatory Action Planning Increases from 3 to 10 Years of Age in Typically Developing Children

    ERIC Educational Resources Information Center

    Jongbloed-Pereboom, Marjolein; Nijhuis-van der Sanden, Maria W. G.; Saraber-Schiphorst, Nicole; Craje, Celine; Steenbergen, Bert

    2013-01-01

    The primary aim of this study was to assess the development of action planning in a group of typically developing children aged 3 to 10 years (N = 351). The second aim was to assess reliability of the action planning task and to relate the results of the action planning task to results of validated upper limb motor performance tests. Participants…

  5. 24 CFR 203.203 - Issuance and nature of insured 10-year protection plans.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Issuance and nature of insured 10-year protection plans. 203.203 Section 203.203 Housing and Urban Development Regulations Relating to... Underwriting Procedures Insured Ten-Year Protection Plans (plan) § 203.203 Issuance and nature of insured...

  6. Fringe-period selection for a multifrequency fringe-projection phase unwrapping method

    NASA Astrophysics Data System (ADS)

    Zhang, Chunwei; Zhao, Hong; Jiang, Kejian

    2016-08-01

    The multi-frequency fringe-projection phase unwrapping method (MFPPUM) is a typical phase unwrapping algorithm for fringe projection profilometry. It has the advantage of being capable of correctly accomplishing phase unwrapping even in the presence of surface discontinuities. If the fringe frequency ratio of the MFPPUM is too large, fringe order error (FOE) may be triggered. FOE will result in phase unwrapping error. It is preferable for the phase unwrapping to be kept correct while the fewest sets of lower frequency fringe patterns are used. To achieve this goal, in this paper a parameter called fringe order inaccuracy (FOI) is defined, dominant factors which may induce FOE are theoretically analyzed, a method to optimally select the fringe periods for the MFPPUM is proposed with the aid of FOI, and experiments are conducted to research the impact of the dominant factors in phase unwrapping and demonstrate the validity of the proposed method. Some novel phenomena are revealed by these experiments. The proposed method helps to optimally select the fringe periods and detect the phase unwrapping error for the MFPPUM.

  7. Periodic nonlinear Fourier transform for fiber-optic communications, Part I: theory and numerical methods.

    PubMed

    Kamalian, Morteza; Prilepsky, Jaroslaw E; Le, Son Thai; Turitsyn, Sergei K

    2016-08-01

    In this work, we introduce the periodic nonlinear Fourier transform (PNFT) method as an alternative and efficacious tool for compensation of the nonlinear transmission effects in optical fiber links. In the Part I, we introduce the algorithmic platform of the technique, describing in details the direct and inverse PNFT operations, also known as the inverse scattering transform for periodic (in time variable) nonlinear Schrödinger equation (NLSE). We pay a special attention to explaining the potential advantages of the PNFT-based processing over the previously studied nonlinear Fourier transform (NFT) based methods. Further, we elucidate the issue of the numerical PNFT computation: we compare the performance of four known numerical methods applicable for the calculation of nonlinear spectral data (the direct PNFT), in particular, taking the main spectrum (utilized further in Part II for the modulation and transmission) associated with some simple example waveforms as the quality indicator for each method. We show that the Ablowitz-Ladik discretization approach for the direct PNFT provides the best performance in terms of the accuracy and computational time consumption. PMID:27505799

  8. Periodic dielectric structure for production of photonic band gap and method for fabricating the same

    DOEpatents

    Ozbay, Ekmel; Tuttle, Gary; Michel, Erick; Ho, Kai-Ming; Biswas, Rana; Chan, Che-Ting; Soukoulis, Costas

    1995-01-01

    A method for fabricating a periodic dielectric structure which exhibits a photonic band gap. Alignment holes are formed in a wafer of dielectric material having a given crystal orientation. A planar layer of elongate rods is then formed in a section of the wafer. The formation of the rods includes the step of selectively removing the dielectric material of the wafer between the rods. The formation of alignment holes and layers of elongate rods and wafers is then repeated to form a plurality of patterned wafers. A stack of patterned wafers is then formed by rotating each successive wafer with respect to the next-previous wafer, and then placing the successive wafer on the stack. This stacking results in a stack of patterned wafers having a four-layer periodicity exhibiting a photonic band gap.

  9. Periodic dielectric structure for production of photonic band gap and method for fabricating the same

    DOEpatents

    Ozbay, E.; Tuttle, G.; Michel, E.; Ho, K.M.; Biswas, R.; Chan, C.T.; Soukoulis, C.

    1995-04-11

    A method is disclosed for fabricating a periodic dielectric structure which exhibits a photonic band gap. Alignment holes are formed in a wafer of dielectric material having a given crystal orientation. A planar layer of elongate rods is then formed in a section of the wafer. The formation of the rods includes the step of selectively removing the dielectric material of the wafer between the rods. The formation of alignment holes and layers of elongate rods and wafers is then repeated to form a plurality of patterned wafers. A stack of patterned wafers is then formed by rotating each successive wafer with respect to the next-previous wafer, and then placing the successive wafer on the stack. This stacking results in a stack of patterned wafers having a four-layer periodicity exhibiting a photonic band gap. 42 figures.

  10. Second-order two-scale method for bending behaviors of composite plate with periodic configuration

    NASA Astrophysics Data System (ADS)

    Zhu, Guoqing; Cui, Junzhi

    2010-06-01

    In this paper, the second-order two-scale analysis method for bending behaviors of the plate made from composites with 3-D periodic configuration is presented by means of construction way. It can capture the microscopic 3-D mechanics behaviors caused from 3-D micro-structures. First, directly starting from the 3-D elastic plate model of composite materials with 3-D periodic configuration, three cell models are defined, and correspondingly the three classes of cell functions only defined on 3 normalized cells are constructed. And then, the effective homogenization parameters of composites are calculated from those local functions, it leads to a 2-D homogenized laminar plate problem. Next, to solve it the homogenization solution is obtained. Finally, the second-order two-scale solution is constructed from the micro-cell functions and the homogenization solution.

  11. Second-Order Two-Scale Method for Bending Behaviors of Composite Plate with Periodic Configuration

    NASA Astrophysics Data System (ADS)

    Zhu, Guoqing; Cui, Junzhi

    2010-05-01

    In this paper, the second-order two-scale analysis method for bending behaviors of the plate made from composites with 3-D periodic configuration is presented by means of construction way. It can capture the microscopic 3-D mechanics behaviors caused from 3-D micro-structures. First, directly starting from the 3-D elastic plate model of composite materials with 3-D periodic configuration, three cell models are defined, and correspondingly the three classes of cell functions only defined on 3 normalized cells are constructed. And then, the effective homogenization parameters of composites are calculated from those local functions, it leads to a 2-D homogenized laminar plate problem. Next, to solve it the homogenization solution is obtained. Finally, the second-order two-scale solution is constructed from the micro-cell functions and the homogenization solution.

  12. The 10-year course of Alcoholics Anonymous participation and long-term outcomes: a follow-up study of outpatient subjects in Project MATCH.

    PubMed

    Pagano, Maria E; White, William L; Kelly, John F; Stout, Robert L; Tonigan, J Scott

    2013-01-01

    This study investigates the 10-year course and impact of Alcoholics Anonymous (AA)-related helping (AAH), step-work, and meeting attendance on long-term outcomes. Data were derived from 226 treatment-seeking alcoholics recruited from an outpatient site in Project MATCH and followed for 10 years post treatment. Alcohol consumption, AA participation, and other-oriented behavior were assessed at baseline, end of the 3-month treatment period, and 1, 3, and 10 years post treatment. Controlling for explanatory baseline and time-varying variables, results showed significant direct effects of AAH and meeting attendance on reduced alcohol outcomes and a direct effect of AAH on improved other-oriented interest. PMID:23327504

  13. The 10 Year Course of AA Participation and Long-Term Outcomes: A Follow-up Study of Outpatient Subjects in Project MATCH

    PubMed Central

    White, William L.; Kelly, John F.; Stout, Robert L.; Carter, Rebecca R.; Tonigan, J. Scott

    2012-01-01

    This study investigates the 10-year course and impact of AA-related helping (AAH), step-work, and meeting attendance on long-term outcomes. Data were derived from 226 treatment-seeking alcoholics recruited from an outpatient site in Project MATCH and followed for 10 years post-treatment. Alcohol consumption, AA participation, and other-oriented behavior were assessed at baseline, end of the 3-month treatment period, and one year, three years, and 10 years post-treatment. Controlling for explanatory baseline and time-varying variables, results showed significant direct effects of AAH and meeting attendance on reduced alcohol outcomes and a direct effect of AAH on improved other-oriented interest. PMID:23327504

  14. DNS of Flows over Periodic Hills using a Discontinuous-Galerkin Spectral-Element Method

    NASA Technical Reports Server (NTRS)

    Diosady, Laslo T.; Murman, Scott M.

    2014-01-01

    Direct numerical simulation (DNS) of turbulent compressible flows is performed using a higher-order space-time discontinuous-Galerkin finite-element method. The numerical scheme is validated by performing DNS of the evolution of the Taylor-Green vortex and turbulent flow in a channel. The higher-order method is shown to provide increased accuracy relative to low-order methods at a given number of degrees of freedom. The turbulent flow over a periodic array of hills in a channel is simulated at Reynolds number 10,595 using an 8th-order scheme in space and a 4th-order scheme in time. These results are validated against previous large eddy simulation (LES) results. A preliminary analysis provides insight into how these detailed simulations can be used to improve Reynoldsaveraged Navier-Stokes (RANS) modeling

  15. Reproducibility and Relative Validity of a Short Food Frequency Questionnaire in 9-10 Year-Old Children.

    PubMed

    Saeedi, Pouya; Skeaff, Sheila A; Wong, Jyh Eiin; Skidmore, Paula M L

    2016-01-01

    The aim of this study was to assess the reproducibility and validity of a non-quantitative 28-item food frequency questionnaire (FFQ). Children aged 9-10 years (n = 50) from three schools in Dunedin, New Zealand, completed the FFQ twice and a four-day estimated food diary (4DEFD) over a two-week period. Intraclass correlation coefficients (ICC) and Spearman's correlation coefficients (SCC) were used to determine reproducibility and validity of the FFQ, respectively. Weekly intakes were estimated for each food item and aggregated into 23 food items/groups. More than half of the food items/groups (52.2%) had an ICC ≥0.5. The median SCC between FFQ administrations was 0.66 (ranging from 0.40 for processed meat to 0.82 for sweets and non-dairy drinks). Cross-classification analysis between the first FFQ and 4DEFD for ranking participants into thirds showed that breakfast cereals had the highest agreement (54.0%) and pasta the lowest (34.0%). In validity analyses, 70% of food items/groups had a SCC ≥0.3. Results indicate that the FFQ is a useful tool for ranking children according to food items/groups intake. The low respondent burden and relative simplicity of the FFQ makes it suitable for use in large cohort studies of 9-10 year-old children in New Zealand. PMID:27164137

  16. Reproducibility and Relative Validity of a Short Food Frequency Questionnaire in 9-10 Year-Old Children.

    PubMed

    Saeedi, Pouya; Skeaff, Sheila A; Wong, Jyh Eiin; Skidmore, Paula M L

    2016-01-01

    The aim of this study was to assess the reproducibility and validity of a non-quantitative 28-item food frequency questionnaire (FFQ). Children aged 9-10 years (n = 50) from three schools in Dunedin, New Zealand, completed the FFQ twice and a four-day estimated food diary (4DEFD) over a two-week period. Intraclass correlation coefficients (ICC) and Spearman's correlation coefficients (SCC) were used to determine reproducibility and validity of the FFQ, respectively. Weekly intakes were estimated for each food item and aggregated into 23 food items/groups. More than half of the food items/groups (52.2%) had an ICC ≥0.5. The median SCC between FFQ administrations was 0.66 (ranging from 0.40 for processed meat to 0.82 for sweets and non-dairy drinks). Cross-classification analysis between the first FFQ and 4DEFD for ranking participants into thirds showed that breakfast cereals had the highest agreement (54.0%) and pasta the lowest (34.0%). In validity analyses, 70% of food items/groups had a SCC ≥0.3. Results indicate that the FFQ is a useful tool for ranking children according to food items/groups intake. The low respondent burden and relative simplicity of the FFQ makes it suitable for use in large cohort studies of 9-10 year-old children in New Zealand.

  17. Reproducibility and Relative Validity of a Short Food Frequency Questionnaire in 9–10 Year-Old Children

    PubMed Central

    Saeedi, Pouya; Skeaff, Sheila A.; Wong, Jyh Eiin; Skidmore, Paula M. L.

    2016-01-01

    The aim of this study was to assess the reproducibility and validity of a non-quantitative 28-item food frequency questionnaire (FFQ). Children aged 9–10 years (n = 50) from three schools in Dunedin, New Zealand, completed the FFQ twice and a four-day estimated food diary (4DEFD) over a two-week period. Intraclass correlation coefficients (ICC) and Spearman’s correlation coefficients (SCC) were used to determine reproducibility and validity of the FFQ, respectively. Weekly intakes were estimated for each food item and aggregated into 23 food items/groups. More than half of the food items/groups (52.2%) had an ICC ≥0.5. The median SCC between FFQ administrations was 0.66 (ranging from 0.40 for processed meat to 0.82 for sweets and non-dairy drinks). Cross-classification analysis between the first FFQ and 4DEFD for ranking participants into thirds showed that breakfast cereals had the highest agreement (54.0%) and pasta the lowest (34.0%). In validity analyses, 70% of food items/groups had a SCC ≥0.3. Results indicate that the FFQ is a useful tool for ranking children according to food items/groups intake. The low respondent burden and relative simplicity of the FFQ makes it suitable for use in large cohort studies of 9–10 year-old children in New Zealand. PMID:27164137

  18. [Analytical, toxicological and forensic aspects of drug-facilitated crimes: 10 years of experience].

    PubMed

    Pépin, G

    2010-03-01

    Although being a relatively old phenomenon, drug-facilitated crime has been well described over the past 20 years as being the administration without the knowledge of the victim of a psychoactive substance in criminal purposes (rape, robbery, theft, money extortion, even murder). Drug-facilitated crime involves also mistreatment of older people or children treated by their parents in order to obtain sedation. Drug-facilitated crimes are often difficult to solve mainly due to analytical issues. Since 10 years, we developed and improved specific methods using LC-MS/MS (benzodiazepines, neuroleptics) and GC-MS/MS (GHB, cannabis) to detect the drugs involved in such crimes. After the intake of a low dosage of a particular drug, those methods allow to detect the analyte of interest up to 3-5 days in blood, 10-15 days in urine, and more than 1 year in hair. In drug-facilitated crime cases, blood and urine are frequently collected too late, more than 12 h after the drug intake and in some cases with a delay greater than 48 h after the event. Thus, the most used molecules are undetectable by the techniques classically used in a laboratory of biology. Moreover, a "good" compound that can be used to commit a drug-facilitated crime usually possesses a short elimination half-life and amnesic properties, so that the victim is less able to accurately recall the circumstances under which the offence occurred. The recent progress in analytical toxicology, particularly for laboratories working in the field of forensic toxicology, permits to elucidate many cases of drug-facilitated crimes. Heaven to the introduction of the sequential analysis of hair and the use of sophisticated analytical techniques such as tandem mass-spectrometry for the toxicologist to bring the scientific proof to the applicant authorities in the description of the criminal act and to confuse the offender. The author presents the results of 583 presumed cases of drug-facilitated crimes analyzed by his

  19. 10-year Field Measurement Program of Post-Wildfire Tree Root Decay, Kootenay National Park, British Columbia

    NASA Astrophysics Data System (ADS)

    Martin, Y. E.; Johnson, E. A.; Kroeker, S.

    2013-12-01

    Tree population dynamics in subalpine forests of the Canadian Rockies are dominated by wildfire disturbance (Gallaway et al., 2009), with wildfire return intervals most often being shorter than the potential lifespan of trees. These crown wildfires kill all trees, resulting in a gradual decline of tree root strength in shallow soils in the immediate post-wildfire years. Tree root networks have been shown to provide mechanical reinforcement of shear strength in shallow soils (Schmidt et al., 2001; Roering et al., 2003). Therefore, decreases in tree root reinforcement in post-wildfire years may result in increased debris slide and debris flow activity during this time period (e.g., Benda and Dunne, 1997; Martin, 2007; Jackson and Roering, 2009). To our knowledge, our study is the first that has measured tree root strength annually for 10 years following a crown wildfire to document the nature and timing of tree root decay. Suggestions have been made that studies documenting the decay of tree roots following timber harvesting provide a reasonable analogue for post-wildfire tree root decay; drainage basin modeling studies considering hillslope erosion resulting from episodic wildfires have had to rely on this assumption (e.g., Benda and Dunne, 1997; Martin, 2007). Herein, we present our annual field measurements of post-wildfire tree root strength made over the past 10 years at a post-wildfire site in Kootenay National Park, Canadian Rockies. The episodic nature of crown wildfire occurrence over time in these forests results in periods of tree root decay in the immediate post-fire years, and an associated susceptibility for mass wasting during these time periods. In July 2003, two large crown fires were ignited by lightning in Kootenay National Park, British Columbia, Canada and merged to burn approximately 17 000 hectares. Our field measurements were made in the subalpine forest of Hawk Creek drainage basin, Kootenay National Park. Measurements of tree root

  20. An Effective Method of Introducing the Periodic Table as a Crossword Puzzle at the High School Level

    ERIC Educational Resources Information Center

    Joag, Sushama D.

    2014-01-01

    A simple method to introduce the modern periodic table of elements at the high school level as a game of solving a crossword puzzle is presented here. A survey to test the effectiveness of this new method relative to the conventional method, involving use of a wall-mounted chart of the periodic table, was conducted on a convenience sample. This…

  1. Three-dimensional periodic complex structures in soft matter: investigation using scattering methods.

    PubMed

    Impéror-Clerc, Marianne

    2012-10-01

    Three-dimensional periodic complex structures are encountered in various soft matter systems such as liquid crystals, block-copolymer phases and the related nano-structured materials. Here, we review several well-defined topologies: two-dimensional hexagonal phase, three-dimensional packing of spheres, tetrahedral close packing (tcp) bi-continuous and tri-continuous cubic phases. We illustrate how small-angle X-ray scattering experiments help us to investigate these different structures and introduce the main available structural models based on both direct and inverse methods.

  2. Three-dimensional periodic complex structures in soft matter: investigation using scattering methods

    PubMed Central

    Impéror-Clerc, Marianne

    2012-01-01

    Three-dimensional periodic complex structures are encountered in various soft matter systems such as liquid crystals, block-copolymer phases and the related nano-structured materials. Here, we review several well-defined topologies: two-dimensional hexagonal phase, three-dimensional packing of spheres, tetrahedral close packing (tcp) bi-continuous and tri-continuous cubic phases. We illustrate how small-angle X-ray scattering experiments help us to investigate these different structures and introduce the main available structural models based on both direct and inverse methods. PMID:24098843

  3. Apparatus and method for automatically and periodically introducing a fluid into a producing oil well

    SciTech Connect

    Soderberg, P.B.

    1987-07-21

    This patent describes a method for periodically and automatically introducing a fluid into a producing well through a tubing drain valve in a string of production tubing, comprising: disabling temporarily, automatically and at periodic time intervals a string of sucker rods disposed within the string of production tubing between a surface-located means for operating the sucker rods and a downhole pump so that a mechanical actuator on the string of sucker rods is stopped in a predetermined position on one side of a lever means of the tubing drain valve. An apparatus is described useful for periodically and automatically introducing a fluid into a producing well through a tubing drain valve located in a production string, comprising: a string of production tubing suitable for suspension in a producing well; surface and downhole pumps connected by a string of sucker rods for lifting well fluids through the production tubing; a tubing drain valve within the production string, the tubing drain valve actuated to its opened position by increased pressure within the production tubing and actuated to its closed position by movement of a lever means of the value; means in communication with the interior of the production tubing for pressurizing the production tubing to a pressure sufficient to open the tubing drain valve; means in communication with the interior of the production tubing for introducing a fluid into the production tubing; an actuator means disposed on the string of sucker rods for mechanically closing the tubing drain valve by cooperation with the lever means on the valve; and means for controlling automatically the operation of the above components at periodic time intervals for automatically conveying a fluid into the production tubing and through the tubing drain valve.

  4. The relationship between household income and dietary intakes of 1-10 year old urban Malaysian

    PubMed Central

    Lin, Khor Geok; Sariman, Sarina; Lee, Huang Soo; Siew, Chin Yit; Mohd Yusof, Barakatun Nisak; Mun, Chan Yoke; Mohamad, Maznorila

    2015-01-01

    BACKGROUND/OBJECTIVES Diet plays an important role in growth and development of children. However, dietary intakes of children living in either rural or urban areas can be influenced by household income. This cross-sectional study examined energy, nutrient and food group intakes of 749 urban children (1-10 years old) by household income status. SUBJECTS/METHODS Children's dietary intakes were obtained using food recall and record for two days. Diet adequacy was assessed based on recommended intakes of energy and nutrients and food group servings. RESULTS For toddlers, all nutrients except dietary fiber (5.5 g) exceeded recommended intakes. Among older children (preschoolers and school children), calcium (548 mg, 435 mg) and dietary fiber (7.4 g, 9.4 g) did not meet recommendations while percentage of energy from total fat and saturated fats exceeded 30% and 10%, respectively. The mean sodium intakes of preschoolers (1,684 mg) and school children (2,000 mg) were relatively high. Toddlers in all income groups had similar energy and nutrient intakes and percentages meeting the recommended intakes. However, low income older children had lowest intakes of energy (P < 0.05) and most nutrients (P < 0.05) and highest proportions that did not meet recommended energy and nutrient intakes. For all food groups, except milk and dairy products, all age groups had mean intakes below the recommended servings. Compared to middle and high income groups, low income preschoolers had the lowest mean intake of fruits (0.07 serving), meat/poultry (0.78 serving) and milk/dairy products (1.14 serving) while low income toddlers and school children had the least mean intake of fruits (0.09 serving) and milk/dairy products (0.54 serving), respectively. CONCLUSION Low socioeconomic status, as indicated by low household income, could limit access to adequate diets, particularly for older children. Parents and caregivers may need dietary guidance to ensure adequate quantity and quality of home

  5. Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children

    PubMed Central

    Bibiloni, Maria del Mar; Salas, Rogelio; Novelo, Hilda I.; Villarreal, Jesús Z.; Sureda, Antoni; Tur, Josep A.

    2015-01-01

    Background and Aims The increase in overweight and obese children may be linked to increased rates of dyslipidaemia. The aim was to assess the prevalence of dyslipidaemia and associated risk factors among the Northern Mexican child population. Methods and Results Four hundred and fifty-one subjects aged between 2 and 10 (47.5% girls) took part in the Nuevo León State Survey of Nutrition and Health 2011–2012. According to the 2011 Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, serum lipid levels (mg/dL) were categorized into three subgroups (acceptable, borderline-high/low or high/low) as follows: TChol: acceptable <170, borderline-high 170–199, high ≥200; LDL-chol: acceptable <110, borderline-high 110–129, high ≥130; non-HDL-chol: acceptable <120, borderline-high 120–144, high ≥145; HDL-chol: acceptable >45, borderline-low 40–45, low <40; and TG: acceptable <75, borderline-high 75–99, high ≥100 in ≤9 year-old children, and acceptable <90, borderline-high 90–129, and high ≥130 in 10 year-old children. The overall prevalence of borderline-high + high TG, non-HDL-chol, TChol, and LDL-chol was 63.0%, 44.1%, 43.5%, and 29.9%, respectively. The overall prevalence of borderline-low + low HDL-chol was 46.3%. The overall frequency of dyslipidaemia was 54.3%. Thirteen children (2.9%) had all five symptoms of dyslipidaemia. The most common dyslipidaemia was high TG in combination (26.2%) and in isolation (10.6%). Conclusions Half of the children had at least one abnormal lipid concentration. A high TG level was the most frequent dyslipidaemia. Obesity was associated with the occurrence of at least one abnormal lipid level. These findings emphasize the need to pay further attention to the prevention of cardiovascular disease and obesity from an early age. PMID:25793380

  6. Finite difference method to find period-one gait cycles of simple passive walkers

    NASA Astrophysics Data System (ADS)

    Dardel, Morteza; Safartoobi, Masoumeh; Pashaei, Mohammad Hadi; Ghasemi, Mohammad Hassan; Navaei, Mostafa Kazemi

    2015-01-01

    Passive dynamic walking refers to a class of bipedal robots that can walk down an incline with no actuation or control input. These bipeds are sensitive to initial conditions due to their style of walking. According to small basin of attraction of passive limit cycles, it is important to start with an initial condition in the basin of attraction of stable walking (limit cycle). This paper presents a study of the simplest passive walker with point and curved feet. A new approach is proposed to find proper initial conditions for a pair of stable and unstable period-one gait limit cycles. This methodology is based on finite difference method which can solve the nonlinear differential equations of motion on a discrete time. Also, to investigate the physical configurations of the walkers and the environmental influence such as the slope angle, the parameter analysis is applied. Numerical simulations reveal the performance of the presented method in finding two stable and unstable gait patterns.

  7. Periodical capacity setting methods for make-to-order multi-machine production systems

    PubMed Central

    Altendorfer, Klaus; Hübl, Alexander; Jodlbauer, Herbert

    2014-01-01

    The paper presents different periodical capacity setting methods for make-to-order, multi-machine production systems with stochastic customer required lead times and stochastic processing times to improve service level and tardiness. These methods are developed as decision support when capacity flexibility exists, such as, a certain range of possible working hours a week for example. The methods differ in the amount of information used whereby all are based on the cumulated capacity demand at each machine. In a simulation study the methods’ impact on service level and tardiness is compared to a constant provided capacity for a single and a multi-machine setting. It is shown that the tested capacity setting methods can lead to an increase in service level and a decrease in average tardiness in comparison to a constant provided capacity. The methods using information on processing time and customer required lead time distribution perform best. The results found in this paper can help practitioners to make efficient use of their flexible capacity. PMID:27226649

  8. Assessing the accuracy of the isotropic periodic sum method through Madelung energy computation

    NASA Astrophysics Data System (ADS)

    Ojeda-May, Pedro; Pu, Jingzhi

    2014-04-01

    We tested the isotropic periodic sum (IPS) method for computing Madelung energies of ionic crystals. The performance of the method, both in its nonpolar (IPSn) and polar (IPSp) forms, was compared with that of the zero-charge and Wolf potentials [D. Wolf, P. Keblinski, S. R. Phillpot, and J. Eggebrecht, J. Chem. Phys. 110, 8254 (1999)]. The results show that the IPSn and IPSp methods converge the Madelung energy to its reference value with an average deviation of ˜10-4 and ˜10-7 energy units, respectively, for a cutoff range of 18-24a (a/2 being the nearest-neighbor ion separation). However, minor oscillations were detected for the IPS methods when deviations of the computed Madelung energies were plotted on a logarithmic scale as a function of the cutoff distance. To remove such oscillations, we introduced a modified IPSn potential in which both the local-region and long-range electrostatic terms are damped, in analogy to the Wolf potential. With the damped-IPSn potential, a smoother convergence was achieved. In addition, we observed a better agreement between the damped-IPSn and IPSp methods, which suggests that damping the IPSn potential is in effect similar to adding a screening potential in IPSp.

  9. Performance of the radial semblance method for the location of very long period volcanic signals

    USGS Publications Warehouse

    Almendros, J.; Chouet, B.

    2003-01-01

    We investigate the performance of a source location method that combines multichannel semblance and particle motions and is being increasingly used to obtain estimates of the source locations of very long period (VLP) seismic signals recorded on volcanoes. The method makes use of the radial particle motions and large wavelengths that characterize the VLP events. To assess the capabilities of this radial semblance method, and to better understand its limitations, we quantify the effects of window length, noise contents of the signal, inaccurate velocity models, receiver coverage, and orientation errors in the horizontal components of the receivers. Our results show that the semblance method performs best when (1) the noise level is low enough to allow a good characterization of the waveforms, (2) the sources are located at distances between one half of the average receiver spacing and about two times the network aperture, and (3) the orientations of the horizontal components of the seismometers are known with relative accuracy. When these requirements are met, the radial semblance method constitutes an adequate tool to obtain preliminary locations of VLP volcanic signals recorded by broadband networks. Moreover, we provide a formula to determine the radial semblance level that should be used to define error regions associated to the estimated source locations.

  10. A Unique Case of Mycophenolate Induced Colitis after 10 Years of Use

    PubMed Central

    Govil, Yogesh

    2016-01-01

    A 31-year-old female with a history of lupus nephritis on Hydroxychloroquine, Prednisone, and Mycophenolate Mofetil (MMF) for 10 years presented to the hospital for ankle swelling. On day four, she started to have severe, nonbloody, watery diarrhea with abdominal distension and tenderness. Stool PCR was negative for C. difficile. CT abdomen/pelvis showed gaseous distension of the colon without any obstruction. Flexible sigmoidoscopy revealed a normal looking mucosa. Histopathology showed crypt atrophy and increased crypt apoptosis, consistent with MMF colitis. The diarrhea resolved three days after stopping MMF. Although generally well tolerated, diarrhea is a common side effect of MMF. Most cases occur in the first six months of starting MMF. This case is unique because it describes MMF colitis in lupus after more than 10 years. Thus, MMF colitis should be considered as a differential in patients taking it, regardless of the duration of use.

  11. A Unique Case of Mycophenolate Induced Colitis after 10 Years of Use.

    PubMed

    Goyal, Abhinav; Salahuddin, Moiz; Govil, Yogesh

    2016-01-01

    A 31-year-old female with a history of lupus nephritis on Hydroxychloroquine, Prednisone, and Mycophenolate Mofetil (MMF) for 10 years presented to the hospital for ankle swelling. On day four, she started to have severe, nonbloody, watery diarrhea with abdominal distension and tenderness. Stool PCR was negative for C. difficile. CT abdomen/pelvis showed gaseous distension of the colon without any obstruction. Flexible sigmoidoscopy revealed a normal looking mucosa. Histopathology showed crypt atrophy and increased crypt apoptosis, consistent with MMF colitis. The diarrhea resolved three days after stopping MMF. Although generally well tolerated, diarrhea is a common side effect of MMF. Most cases occur in the first six months of starting MMF. This case is unique because it describes MMF colitis in lupus after more than 10 years. Thus, MMF colitis should be considered as a differential in patients taking it, regardless of the duration of use. PMID:27668102

  12. Advanced Trauma Life Support (ATLS) in Hungary; The First 10 Years.

    PubMed

    Varga, Endre; Endre, Endre; Kószó, Balázs; Pető, Zoltán; Ágoston, Zsuzsanna; Gyura, Erika; Nardai, Gábor; Boa, Kristóf; Süveges, Gábor

    2016-01-01

    Advanced Trauma Life Support (ATLS) programs are recognized as the standard educational trauma program worldwide. Data suggest that ATLS has a positive impact on the value of trauma care. The ATLS Hungary program has been started in 2005, celebrating its 10-year anniversary this year. In the present brief communication a brief overview is provided on the program.Student evaluation and statistical data about the participants were collected throughout the 10-year history of the Hungarian program.Student evaluation shows a high level of satisfaction amongst the participating doctors. Most participants are working in higher level centers. The Hungarian program shows good quality according to the participants. Establishing at least one new center is crucial to be able to provide the course for every professional interested in it or required to take it. PMID:27162927

  13. A Unique Case of Mycophenolate Induced Colitis after 10 Years of Use

    PubMed Central

    Govil, Yogesh

    2016-01-01

    A 31-year-old female with a history of lupus nephritis on Hydroxychloroquine, Prednisone, and Mycophenolate Mofetil (MMF) for 10 years presented to the hospital for ankle swelling. On day four, she started to have severe, nonbloody, watery diarrhea with abdominal distension and tenderness. Stool PCR was negative for C. difficile. CT abdomen/pelvis showed gaseous distension of the colon without any obstruction. Flexible sigmoidoscopy revealed a normal looking mucosa. Histopathology showed crypt atrophy and increased crypt apoptosis, consistent with MMF colitis. The diarrhea resolved three days after stopping MMF. Although generally well tolerated, diarrhea is a common side effect of MMF. Most cases occur in the first six months of starting MMF. This case is unique because it describes MMF colitis in lupus after more than 10 years. Thus, MMF colitis should be considered as a differential in patients taking it, regardless of the duration of use. PMID:27668102

  14. Advanced Trauma Life Support (ATLS) in Hungary; The First 10 Years.

    PubMed

    Varga, Endre; Endre, Endre; Kószó, Balázs; Pető, Zoltán; Ágoston, Zsuzsanna; Gyura, Erika; Nardai, Gábor; Boa, Kristóf; Süveges, Gábor

    2016-01-01

    Advanced Trauma Life Support (ATLS) programs are recognized as the standard educational trauma program worldwide. Data suggest that ATLS has a positive impact on the value of trauma care. The ATLS Hungary program has been started in 2005, celebrating its 10-year anniversary this year. In the present brief communication a brief overview is provided on the program.Student evaluation and statistical data about the participants were collected throughout the 10-year history of the Hungarian program.Student evaluation shows a high level of satisfaction amongst the participating doctors. Most participants are working in higher level centers. The Hungarian program shows good quality according to the participants. Establishing at least one new center is crucial to be able to provide the course for every professional interested in it or required to take it.

  15. Germination rate of Phyllospadix japonicus seeds relative to storage methods and periods

    NASA Astrophysics Data System (ADS)

    Park, Jung-Im; Lee, Kun-Seop; Son, Min Ho

    2014-03-01

    To determine the optimal storage method and longest possible storage period of Phyllospadix japonicus seeds, we examined post-storage germination rates using different storage methods and periods for P. japonicus seeds harvested in Korean coastal waters. P. japonicus seeds are classified as recalcitrant seeds with an average moisture content of 45.4%. Germination rates of P. japonicus seeds stored in seawater at 4 °C, seawater at room temperature with air supply, and an aquarium with continuous seawater circulation ranged from 35.0% to 43.5%, whereas seeds stored in seawater at 30°C, a refrigerator at -20°C, and a desiccator at room temperature did not germinate. Seeds stored at 4°C maintained germination rates of 72.5˜73.0% until 30 days of storage, but showed rapidly decreasing germination rates after 60 days and no germination after 180 days. Since few studies have investigated seed storage of P. japonicus, these results will serve as useful data for seed-based P. japonicus habitat restoration.

  16. A stream-gaging network analysis for the 7-Day, 10-year annual low flow in New Hampshire streams

    USGS Publications Warehouse

    Flynn, Robert H.

    2003-01-01

    The 7-day, 10-year (7Q10) low-flow-frequency statistic is a widely used measure of surface-water availability in New Hampshire. Regression equations and basin-characteristic digital data sets were developed to help water-resource managers determine surface-water resources during periods of low flow in New Hampshire streams. These regression equations and data sets were developed to estimate streamflow statistics for the annual and seasonal low-flow-frequency, and period-of-record and seasonal period-of-record flow durations. generalized-least-squares (GLS) regression methods were used to develop the annual 7Q10 low-flow-frequency regression equation from 60 continuous-record stream-gaging stations in New Hampshire and in neighboring States. In the regression equation, the dependent variables were the annual 7Q10 flows at the 60 stream-gaging stations. The independent (or predictor) variables were objectively selected characteristics of the drainage basins that contribute flow to those stations. In contrast to ordinary-least-squares (OLS) regression analysis, GLS-developed estimating equations account for differences in length of record and spatial correlations among the flow-frequency statistics at the various stations. A total of 93 measurable drainage-basin characteristics were candidate independent variables. On the basis of several statistical parameters that were used to evaluate which combination of basin characteristics contribute the most to the predictive power of the equations, three drainage-basin characteristics were determined to be statistically significant predictors of the annual 7Q10: (1) total drainage area, (2) mean summer stream-gaging station precipitation from 1961 to 90, and (3) average mean annual basinwide temperature from 1961 to 1990. To evaluate the effectiveness of the stream-gaging network in providing regional streamflow data for the annual 7Q10, the computer program GLSNET (generalized-least-squares NETwork) was used to analyze the

  17. Monitoring the affordability of healthy eating: a case study of 10 years of the Illawarra Healthy Food Basket.

    PubMed

    Williams, Peter

    2010-11-01

    Healthy food baskets have been used around the world for a variety of purposes, including: examining the difference in cost between healthy and unhealthy food; mapping the availability of healthy foods in different locations; calculating the minimum cost of an adequate diet for social policy planning; developing educational material on low cost eating and examining trends on food costs over time. In Australia, the Illawarra Healthy Food Basket was developed in 2000 to monitor trends in the affordability of healthy food compared to average weekly wages and social welfare benefits for the unemployed. It consists of 57 items selected to meet the nutritional requirements of a reference family of five. Bi-annual costing from 2000-2009 has shown that the basket costs have increased by 38.4% in the 10-year period, but that affordability has remained relatively constant at around 30% of average household incomes. PMID:22254001

  18. The Future of Federated Search, or What Will the World Look like in 10 Years

    ERIC Educational Resources Information Center

    Turner, Rich

    2009-01-01

    In this article, the author contends that in 10 years, federated search--or search of any kind for that matter--won't exist. He elaborates that the "function" of search will exist--but not in a context with which anyone is familiar today. So if "search" doesn't exist in 2018, how will people find the information that they need across vast volumes…

  19. Perinatal air pollution exposure and development of asthma from birth to age 10 years.

    PubMed

    Sbihi, Hind; Tamburic, Lillian; Koehoorn, Mieke; Brauer, Michael

    2016-04-01

    Within-city variation in air pollution has been associated with childhood asthma development, but findings have been inconsistent. We examined whether perinatal air pollution exposure affected asthma onset during "pre-school and "school age" periods in a population-based birth cohort.65,254 children born between 1999 and 2002 in the greater Vancouver metropolitan region were followed until age 10 years using linked administrative health databases. Asthma cases were sex- and age-matched to five randomly chosen controls. Associations between exposure to air pollutants estimated with different methods (interpolation (inverse-distance weighted (IDW)), land use regression, proximity) and incident asthma during the pre-school (0-5 years) and school age (6-10 years) periods were estimated with conditional logistic regression.6948 and 1711 cases were identified during the pre-school and school age periods, respectively. Following adjustment for birthweight, gestational period, household income, parity, breastfeeding at discharge, maternal age and education, asthma risk during the pre-school years was increased by traffic pollution (adjusted odds ratio using IDW method per interquartile increase (95% CI): nitric oxide 1.06 (1.01-1.11), nitrogen dioxide 1.09 (1.04-1.13) and carbon monoxide 1.05 (1.01-1.1)). Enhanced impacts were observed amongst low-term-birthweight cases. Associations were independent of surrounding residential greenness.Within-city air pollution variation was associated with new asthma onset during the pre-school years.

  20. Long-Term Effects of Synthetic versus Analytic Phonics Teaching on the Reading and Spelling Ability of 10 Year Old Boys and Girls

    ERIC Educational Resources Information Center

    Johnston, Rhona S.; McGeown, Sarah; Watson, Joyce E.

    2012-01-01

    A comparison was made of 10-year-old boys and girls who had learnt to read by analytic or synthetic phonics methods as part of their early literacy programmes. The boys taught by the synthetic phonics method had better word reading than the girls in their classes, and their spelling and reading comprehension was as good. In contrast, with analytic…

  1. Evaluation of fire-safety programs that use 10-year smoke alarms.

    PubMed

    Jackson, Mark; Wilson, Jonathan; Akoto, Judith; Dixon, Sherry; Jacobs, David E; Ballesteros, Michael F

    2010-10-01

    The Centers for Disease Control and Prevention began funding a Smoke Alarm Installation and Fire Safety Education (SAIFE) program in 1998. This program involves the installation of lithium-powered "10-year" smoke alarms in homes at high risk for fires and injuries. This study aimed to (1) determine among original SAIFE homes if the lithium-powered alarms were still present and functional 8-10 years after installation and (2) understand factors related to smoke alarm presence and functionality. Data on a total of 384 homes and 601 smoke alarms in five states were collected and analyzed. Only one-third of alarms were still functional; 37% of installed alarms were missing; and 30% of alarms were present, but not functioning. Alarms were less likely to be functioning if they were installed in the kitchen and if homes had a different resident at follow-up. Of the 351 alarms that were present and had a battery at the time of the evaluation, only 21% contained lithium-powered batteries. Of these, 78% were still functioning. Programs that install lithium-powered alarms should use units that have sealed-in batteries and "hush" buttons. Additionally, education should be given on smoke alarm maintenance that includes a message that batteries in these alarms should not be replaced. Lithium-powered smoke alarms should last up to 10 years if maintained properly. PMID:20177753

  2. Parental stress and perceived vulnerability at 5 and 10 years after pediatric SCT.

    PubMed

    Vrijmoet-Wiersma, C M J; Egeler, R M; Koopman, H M; Bresters, D; Norberg, A L; Grootenhuis, M A

    2010-06-01

    With the aim of assessing parental stress after SCT, 73 parents of children and adolescents who underwent SCT 5 or 10 years ago responded to questionnaires on general distress (General Health Questionnaire (GHQ)), disease-related stress (Pediatric Inventory for Parents-short form (PIP-SF)) and perceptions of child vulnerability (Child Vulnerability Scale (CVS)). General distress scores were comparable with the reference groups, but 40% of the mothers at 5 years after SCT reported increased stress levels as compared with 26% in the community-based reference group. Disease-related stress was comparable with the reference group of parents of children who were just off cancer treatment, 5 years after SCT. At 10 years after SCT, scores were lower than the reference group. Perceived child vulnerability did diminish over time, but remained high in parents of SCT survivors, compared with parents of healthy children: 96% of the parents at 5 years after SCT and 76% of the parents at 10 years after SCT scored above the cutoff point. Perceived vulnerability was found to be a predictor for parental disease-related stress. To conclude, although most parents of SCT survivors are resilient, the majority of parents perceive their child to be much more vulnerable as compared with parents of healthy children. This perception is associated with disease-related stress and may induce overprotective parenting. PMID:19881554

  3. Long Term Clinical Prognostic Factors in Relapsing-Remitting Multiple Sclerosis: Insights from a 10-Year Observational Study

    PubMed Central

    Ehling, Rainer; Lutterotti, Andreas; Hegen, Harald; Di Pauli, Franziska; Auer, Michael; Deisenhammer, Florian; Reindl, Markus; Berger, Thomas

    2016-01-01

    Background Multiple sclerosis (MS) has a highly heterogenic course making prediction of long term outcome very difficult. Objective The objective was to evaluate current and identify additional clinical factors that are linked to long term outcome of relapsing-remitting MS assessed by disability status 10 years after disease onset. Methods This observational study included 793 patients with relapsing-remitting MS. Clinical factors hypothesized to influence long term outcome measured by EDSS scores 10 years after disease onset were analysed by Kaplan-Meier-estimates. Multinomial logistic regression models regarding mild (EDSS ≤2.5), moderate (EDSS 3.0–5.5) or severe (EDSS ≥6.0) disability were calculated to correct for confounders. Results Secondary progression was the strongest predictor of severe disability (Hazard ratio [HR] 503.8, 95% confidence interval [CI] 160.0–1580.1); p<0.001). Complete remission of neurological symptoms at onset reduced the risk of moderate disability (HR 0.42; CI 0.23–0.77; p = 0.005), while depression (HR 3.59; CI 1.14–11.24; p = 0.028) and cognitive dysfunction (HR 4.64; CI 1.11–19.50; p = 0.036) 10 years after disease onset were associated with severe disability. Oligoclonal bands and pregnancy were not correlated with disability. Conclusion We were able to identify clinically apparent chronic depression and cognitive dysfunction to be associated with adverse long term outcome in MS and to confirm that pregnancy has no negative impact. Additionally, we emphasize the positive predictive value of complete remission of initial symptoms. PMID:27391947

  4. RECONSTRUCTION OF THE ANTERIOR CRUCIATE LIGAMENT WITH THE CENTRAL THIRD OF THE QUADRICEPS MUSCLE TENDON: ANALYSIS OF 10-YEAR RESULTS

    PubMed Central

    Guimarães, Marcus Valladares; Junior, Lúcio Honório de Carvalho; Terra, Dalton Lopes

    2015-01-01

    Objective: Assess clinical results using two different protocols, 10 years after ACL reconstruction surgery with the central third of quadriceps muscle tendon (QT). Method: Between November /1997 and April/1998, 25 patients were submitted to 25 ACL reconstructions with QT by transtibial technique. The bone portion of the graft was fixated on femoral tunnel with interference screw and the tendinous portion of tibial tunnel with screw with washer. Two patients injured the new when playing soccer. Six patients were not available for follow-up (24%). Seventeen patients were evaluated, 15 men and two women, with mean age at surgery time of 28.53 ± 6.64 years. All patients were examined at six months, one year, and ten years after surgery. Clinical evaluation was made by the Lysholm scale, and the knee evaluation, with the Hospital for Special Surgery scale. Results: The patients had their injuries operated after 9.87 ± 14.42 months of the accident. According to Lysholm scale, the results at the end of the first year were 98.71 ± 2.47 and, after 10 years, 97.35 ± 3.12. Using the Hospital for Special Surgery scale, the mean score was 95.07 ± 5.23 in one year, and 94.87 ± 4.16 in 10 years. All patients returned to their professional activities with the same previous status. Fifteen (88.24%) patients were able to return to their sports activities, one by modifying the practice, while another one switched to another sport. No patient complained of pain on the donor area in the medium and long term. The sports return rate was excellent, and no changes were found on the femoropatellar joint. PMID:27022511

  5. Detection of Periodic Leg Movements by Machine Learning Methods Using Polysomnographic Parameters Other Than Leg Electromyography

    PubMed Central

    Umut, İlhan; Çentik, Güven

    2016-01-01

    The number of channels used for polysomnographic recording frequently causes difficulties for patients because of the many cables connected. Also, it increases the risk of having troubles during recording process and increases the storage volume. In this study, it is intended to detect periodic leg movement (PLM) in sleep with the use of the channels except leg electromyography (EMG) by analysing polysomnography (PSG) data with digital signal processing (DSP) and machine learning methods. PSG records of 153 patients of different ages and genders with PLM disorder diagnosis were examined retrospectively. A novel software was developed for the analysis of PSG records. The software utilizes the machine learning algorithms, statistical methods, and DSP methods. In order to classify PLM, popular machine learning methods (multilayer perceptron, K-nearest neighbour, and random forests) and logistic regression were used. Comparison of classified results showed that while K-nearest neighbour classification algorithm had higher average classification rate (91.87%) and lower average classification error value (RMSE = 0.2850), multilayer perceptron algorithm had the lowest average classification rate (83.29%) and the highest average classification error value (RMSE = 0.3705). Results showed that PLM can be classified with high accuracy (91.87%) without leg EMG record being present. PMID:27213008

  6. Detection of Periodic Leg Movements by Machine Learning Methods Using Polysomnographic Parameters Other Than Leg Electromyography.

    PubMed

    Umut, İlhan; Çentik, Güven

    2016-01-01

    The number of channels used for polysomnographic recording frequently causes difficulties for patients because of the many cables connected. Also, it increases the risk of having troubles during recording process and increases the storage volume. In this study, it is intended to detect periodic leg movement (PLM) in sleep with the use of the channels except leg electromyography (EMG) by analysing polysomnography (PSG) data with digital signal processing (DSP) and machine learning methods. PSG records of 153 patients of different ages and genders with PLM disorder diagnosis were examined retrospectively. A novel software was developed for the analysis of PSG records. The software utilizes the machine learning algorithms, statistical methods, and DSP methods. In order to classify PLM, popular machine learning methods (multilayer perceptron, K-nearest neighbour, and random forests) and logistic regression were used. Comparison of classified results showed that while K-nearest neighbour classification algorithm had higher average classification rate (91.87%) and lower average classification error value (RMSE = 0.2850), multilayer perceptron algorithm had the lowest average classification rate (83.29%) and the highest average classification error value (RMSE = 0.3705). Results showed that PLM can be classified with high accuracy (91.87%) without leg EMG record being present.

  7. Estimation of the free core nutation period by the sliding-window complex least-squares fit method

    NASA Astrophysics Data System (ADS)

    Zhou, Yonghong; Zhu, Qiang; Salstein, David A.; Xu, Xueqing; Shi, Si; Liao, Xinhao

    2016-05-01

    Estimation of the free core nutation (FCN) period is a challenging prospect. Mostly, two methods, one direct and one indirect, have been applied in the past to address the problem by analyzing the Earth orientation parameters observed by the very long baseline interferometry. The indirect method estimates the FCN period from resonance effects of the FCN on forced nutation terms, whereas the direct method estimates the FCN period using the Fourier Transform (FT) approach. However, the FCN period estimated by the direct FT technique suffers from the non-stationary characteristics of celestial pole offsets (CPO). In this study, the FCN period is estimated by another direct method, i.e., the sliding-window complex least-squares fit method (SCLF). The estimated values of the FCN period for the full set of 1984.0-2014.0 and four subsets (1984.0-2000.0, 2000.0-2014.0, 1984.0-1990.0, 1990.0-2014.0) range from -428.8 to -434.3 mean solar days. From the FT to the SCLF method, the estimate uncertainty of the FCN period falls from several tens of days to several days. Thus, the SCLF method may serve as an independent direct way to estimate the FCN period, complementing and validating the indirect resonance method that has been frequently used before.

  8. Reliability of Fitness Tests Using Methods and Time Periods Common in Sport and Occupational Management

    PubMed Central

    Burnstein, Bryan D.; Steele, Russell J.; Shrier, Ian

    2011-01-01

    Context: Fitness testing is used frequently in many areas of physical activity, but the reliability of these measurements under real-world, practical conditions is unknown. Objective: To evaluate the reliability of specific fitness tests using the methods and time periods used in the context of real-world sport and occupational management. Design: Cohort study. Setting: Eighteen different Cirque du Soleil shows. Patients or Other Participants: Cirque du Soleil physical performers who completed 4 consecutive tests (6-month intervals) and were free of injury or illness at each session (n = 238 of 701 physical performers). Intervention(s): Performers completed 6 fitness tests on each assessment date: dynamic balance, Harvard step test, handgrip, vertical jump, pull-ups, and 60-second jump test. Main Outcome Measure(s): We calculated the intraclass coefficient (ICC) and limits of agreement between baseline and each time point and the ICC over all 4 time points combined. Results: Reliability was acceptable (ICC > 0.6) over an 18-month time period for all pairwise comparisons and all time points together for the handgrip, vertical jump, and pull-up assessments. The Harvard step test and 60-second jump test had poor reliability (ICC < 0.6) between baseline and other time points. When we excluded the baseline data and calculated the ICC for 6-month, 12-month, and 18-month time points, both the Harvard step test and 60-second jump test demonstrated acceptable reliability. Dynamic balance was unreliable in all contexts. Limit-of-agreement analysis demonstrated considerable intraindividual variability for some tests and a learning effect by administrators on others. Conclusions: Five of the 6 tests in this battery had acceptable reliability over an 18-month time frame, but the values for certain individuals may vary considerably from time to time for some tests. Specific tests may require a learning period for administrators. PMID:22488138

  9. Mortality rates at 10 years are higher in diabetic than in non-diabetic patients with chronic lower extremity peripheral arterial disease

    PubMed Central

    Mueller, Thomas; Hinterreiter, Franz; Poelz, Werner; Haltmayer, Meinhard; Dieplinger, Benjamin

    2016-01-01

    Patients with lower extremity peripheral artery disease (PAD) have a substantially increased risk for mortality as compared to healthy individuals. We aimed to evaluate the risk for all-cause mortality in PAD patients and in healthy controls during a 10-year follow-up period. Our hypothesis was that the mortality rates at 10 years would differ in diabetic and non-diabetic PAD patients. Our study group consisted of 331 consecutive patients with symptomatic PAD <75 years of age admitted to a tertiary care hospital, including 216 patients without diabetes and 115 with diabetes. Control subjects without atherosclerotic disease were matched to the patients in a 1:1 design by sex, age, and diabetes mellitus status. The outcome measure was all-cause mortality at 10 years. Mortality rates at 10 years were 29% in non-diabetic PAD patients versus 14% in age- and sex-matched non-diabetic controls (risk ratio (RR), 2.31; 95% confidence interval (CI), 1.54–3.47; p<0.001), and 58% in diabetic PAD patients versus 19% in age- and sex-matched diabetic controls (RR, 4.06; 95% CI, 2.67–6.18; p<0.001). Further, PAD patients with diabetes had a significantly increased risk for death within 10 years than did the non-diabetic PAD patients (RR, 2.51; 95% CI, 1.72–3.66; p<0.001). Diabetes was independently associated with outcome, and was the strongest predictor of death in multivariate Cox proportional hazards regression. We conclude that mortality rates at 10 years differ in PAD patients <75 years old with and without diabetes. Our findings suggest that future studies should apply distinct risk assessment strategies in the two PAD subgroups. PMID:27067137

  10. A Method for Calculation of the Upper Limit of Mendeleev's Periodic Table

    NASA Astrophysics Data System (ADS)

    Khazan, Albert

    2010-03-01

    40 years ago some scientists claimed that elements heaviest than No.110 are impossible. The technics got much progress in the last years: element 118 has already been registered. Now, the researchers of Joint Inst. for Nuclear Research (Dubna, Russia) claim that the Periodic Table will end with element 150. However they do not provide theoretical proofs to this claim, because the stability limits of electronic shells they calculated by means of Quantum Mechanics do not answer this question in exact. In contrast, I focused onto the contents of chemical compounds along the Table. The used method is as follows. First, it was found that, given any chemical compound, the contents of any element in it (per 1 gram-atom) is described by the equation of a equilateral hyperbola Y=K/X. Then the scaling coefficient was deduced for the hyperbolas, thus the atomic mass of the last (heaviest) element, 411.66, was found as the abscissa of the ultimate point of the arc drawn by the tops of the hyperbolas. With it, the number of the last element, 155, was found as a consequence. See: Khazan A. Upper Limit in Mendeleev's Periodic Table --- Element No.155. Svenska fysikarkivet, 2009.

  11. Numerical method for the computation of flow in irregular domains that exhibit geometric periodicity using nonstaggered grids

    SciTech Connect

    Kelkar, K.M.; Choudhury, D.; Minkowycz, W.J.

    1997-01-01

    Flows in many engineering applications occur in devices that exhibit geometric periodicity, giving rise to flow characteristics that are spatially periodic. This periodicity can be of two types, translational and rotational. Since the geometries encountered in practice are often complex, periodic boundary-fitted grids are used over a typical module to predict such flows. Nonstaggered grids are frequently used for discretizing the equations governing the flow. These methods employ Cartesian velocities as the primary unknowns. In rotationally periodic geometries, these components themselves are not periodic, necessitating special considerations in incorporating the periodicity conditions over the periodic modules. The aim of the present study is to propose modifications to the conventional nonstaggered grid methods for computations of spatially periodic flows, so that geometric periodicities can be treated in a unified manner. The proposed formulation represents a generalization of the existing formulations for nonstaggered grids and can be applied for the discretization of the governing equations in domains with or without periodicity. The proposed formulation is first validated by comparing the computed solutions with the exact solutions for Couette flows in a parallel-plate channel and a cylindrical annulus. The method is then applied to three physical situations to illustrate its utility.

  12. A periodic energy decomposition analysis method for the investigation of chemical bonding in extended systems

    NASA Astrophysics Data System (ADS)

    Raupach, Marc; Tonner, Ralf

    2015-05-01

    The development and first applications of a new periodic energy decomposition analysis (pEDA) scheme for extended systems based on the Kohn-Sham approach to density functional theory are described. The pEDA decomposes the bonding energy between two fragments (e.g., the adsorption energy of a molecule on a surface) into several well-defined terms: preparation, electrostatic, Pauli repulsion, and orbital relaxation energies. This is complemented by consideration of dispersion interactions via a pairwise scheme. One major extension toward a previous implementation [Philipsen and Baerends, J. Phys. Chem. B 110, 12470 (2006)] lies in the separate discussion of electrostatic and Pauli and the addition of a dispersion term. The pEDA presented here for an implementation based on atomic orbitals can handle restricted and unrestricted fragments for 0D to 3D systems considering periodic boundary conditions with and without the determination of fragment occupations. For the latter case, reciprocal space sampling is enabled. The new method gives comparable results to established schemes for molecular systems and shows good convergence with respect to the basis set (TZ2P), the integration accuracy, and k-space sampling. Four typical bonding scenarios for surface-adsorbate complexes were chosen to highlight the performance of the method representing insulating (CO on MgO(001)), metallic (H2 on M(001), M = Pd, Cu), and semiconducting (CO and C2H2 on Si(001)) substrates. These examples cover diverse substrates as well as bonding scenarios ranging from weakly interacting to covalent (shared electron and donor acceptor) bonding. The results presented lend confidence that the pEDA will be a powerful tool for the analysis of surface-adsorbate bonding in the future, enabling the transfer of concepts like ionic and covalent bonding, donor-acceptor interaction, steric repulsion, and others to extended systems.

  13. A periodic energy decomposition analysis method for the investigation of chemical bonding in extended systems.

    PubMed

    Raupach, Marc; Tonner, Ralf

    2015-05-21

    The development and first applications of a new periodic energy decomposition analysis (pEDA) scheme for extended systems based on the Kohn-Sham approach to density functional theory are described. The pEDA decomposes the bonding energy between two fragments (e.g., the adsorption energy of a molecule on a surface) into several well-defined terms: preparation, electrostatic, Pauli repulsion, and orbital relaxation energies. This is complemented by consideration of dispersion interactions via a pairwise scheme. One major extension toward a previous implementation [Philipsen and Baerends, J. Phys. Chem. B 110, 12470 (2006)] lies in the separate discussion of electrostatic and Pauli and the addition of a dispersion term. The pEDA presented here for an implementation based on atomic orbitals can handle restricted and unrestricted fragments for 0D to 3D systems considering periodic boundary conditions with and without the determination of fragment occupations. For the latter case, reciprocal space sampling is enabled. The new method gives comparable results to established schemes for molecular systems and shows good convergence with respect to the basis set (TZ2P), the integration accuracy, and k-space sampling. Four typical bonding scenarios for surface-adsorbate complexes were chosen to highlight the performance of the method representing insulating (CO on MgO(001)), metallic (H2 on M(001), M = Pd, Cu), and semiconducting (CO and C2H2 on Si(001)) substrates. These examples cover diverse substrates as well as bonding scenarios ranging from weakly interacting to covalent (shared electron and donor acceptor) bonding. The results presented lend confidence that the pEDA will be a powerful tool for the analysis of surface-adsorbate bonding in the future, enabling the transfer of concepts like ionic and covalent bonding, donor-acceptor interaction, steric repulsion, and others to extended systems. PMID:26001445

  14. A periodic energy decomposition analysis method for the investigation of chemical bonding in extended systems

    SciTech Connect

    Raupach, Marc; Tonner, Ralf

    2015-05-21

    The development and first applications of a new periodic energy decomposition analysis (pEDA) scheme for extended systems based on the Kohn-Sham approach to density functional theory are described. The pEDA decomposes the bonding energy between two fragments (e.g., the adsorption energy of a molecule on a surface) into several well-defined terms: preparation, electrostatic, Pauli repulsion, and orbital relaxation energies. This is complemented by consideration of dispersion interactions via a pairwise scheme. One major extension toward a previous implementation [Philipsen and Baerends, J. Phys. Chem. B 110, 12470 (2006)] lies in the separate discussion of electrostatic and Pauli and the addition of a dispersion term. The pEDA presented here for an implementation based on atomic orbitals can handle restricted and unrestricted fragments for 0D to 3D systems considering periodic boundary conditions with and without the determination of fragment occupations. For the latter case, reciprocal space sampling is enabled. The new method gives comparable results to established schemes for molecular systems and shows good convergence with respect to the basis set (TZ2P), the integration accuracy, and k-space sampling. Four typical bonding scenarios for surface-adsorbate complexes were chosen to highlight the performance of the method representing insulating (CO on MgO(001)), metallic (H{sub 2} on M(001), M = Pd, Cu), and semiconducting (CO and C{sub 2}H{sub 2} on Si(001)) substrates. These examples cover diverse substrates as well as bonding scenarios ranging from weakly interacting to covalent (shared electron and donor acceptor) bonding. The results presented lend confidence that the pEDA will be a powerful tool for the analysis of surface-adsorbate bonding in the future, enabling the transfer of concepts like ionic and covalent bonding, donor-acceptor interaction, steric repulsion, and others to extended systems.

  15. Project Energize: intervention development and 10 years of progress in preventing childhood obesity.

    PubMed

    Rush, Elaine; Cairncross, Carolyn; Williams, Margaret Hinepo; Tseng, Marilyn; Coppinger, Tara; McLennan, Steph; Latimer, Kasha

    2016-01-26

    Prevention of childhood obesity is a global priority. The school setting offers access to large numbers of children and the ability to provide supportive environments for quality physical activity and nutrition. This article describes Project Energize, a through-school physical activity and nutrition programme that celebrated its 10-year anniversary in 2015 so that it might serve as a model for similar practices, initiatives and policies elsewhere. The programme was envisaged and financed by the Waikato District Health Board of New Zealand in 2004 and delivered by Sport Waikato to 124 primary schools as a randomised controlled trial from 2005 to 2006. The programme has since expanded to include all 242 primary schools in the Waikato region and 70 schools in other regions, including 53,000 children. Ongoing evaluation and development of Project Energize has shown it to be sustainable (ongoing for >10 years), both effective (lower obesity, higher physical fitness) and cost effective (one health related cost quality adjusted life year between $18,000 and $30,000) and efficient ($45/child/year) as a childhood 'health' programme. The programme's unique community-based approach is inclusive of all children, serving a population that is 42% Māori, the indigenous people of New Zealand. While the original nine healthy eating and seven quality physical activity goals have not changed, the delivery and assessment processes has been refined and the health service adapted over the 10 years of the programme existence, as well as adapted over time to other settings including early childhood education and schools in Cork in Ireland. Evaluation and research associated with the programme delivery and outcomes are ongoing. The dissemination of findings to politicians and collaboration with other service providers are both regarded as priorities.

  16. Project Energize: intervention development and 10 years of progress in preventing childhood obesity.

    PubMed

    Rush, Elaine; Cairncross, Carolyn; Williams, Margaret Hinepo; Tseng, Marilyn; Coppinger, Tara; McLennan, Steph; Latimer, Kasha

    2016-01-01

    Prevention of childhood obesity is a global priority. The school setting offers access to large numbers of children and the ability to provide supportive environments for quality physical activity and nutrition. This article describes Project Energize, a through-school physical activity and nutrition programme that celebrated its 10-year anniversary in 2015 so that it might serve as a model for similar practices, initiatives and policies elsewhere. The programme was envisaged and financed by the Waikato District Health Board of New Zealand in 2004 and delivered by Sport Waikato to 124 primary schools as a randomised controlled trial from 2005 to 2006. The programme has since expanded to include all 242 primary schools in the Waikato region and 70 schools in other regions, including 53,000 children. Ongoing evaluation and development of Project Energize has shown it to be sustainable (ongoing for >10 years), both effective (lower obesity, higher physical fitness) and cost effective (one health related cost quality adjusted life year between $18,000 and $30,000) and efficient ($45/child/year) as a childhood 'health' programme. The programme's unique community-based approach is inclusive of all children, serving a population that is 42% Māori, the indigenous people of New Zealand. While the original nine healthy eating and seven quality physical activity goals have not changed, the delivery and assessment processes has been refined and the health service adapted over the 10 years of the programme existence, as well as adapted over time to other settings including early childhood education and schools in Cork in Ireland. Evaluation and research associated with the programme delivery and outcomes are ongoing. The dissemination of findings to politicians and collaboration with other service providers are both regarded as priorities. PMID:26809555

  17. Maturogenesis of Two Maxillary Central Incisors: A Case Report with 10 Years of Follow Up

    PubMed Central

    Ghorbanzadeh, Abdollah

    2015-01-01

    This case report describes the treatment of two immature maxillary central incisors in a 7-year-old female patient. She suffered complicated crown fracture because of trauma, and the root formation was incomplete. White mineral trioxide aggregate (MTA) was selected as the pulp-capping material after cervical pulpotomy to preserve the pulp tissue vitality and achieve maturogenesis. Follow-up evaluations showed successful treatment in terms of preservation of pulp vitality and demonstrated marked continuous physiological root development. During 10 years of follow-up, both teeth were clinically asymptomatic, and radiographic evaluations showed apparent root regeneration with apical root-end closure without pulp or periapical pathosis. PMID:26622286

  18. SATVI - after 10 years closing in on a new and better vaccine to prevent tuberculosis.

    PubMed

    Hanekom, Willem A; Hawkridge, Anthony; Mahomed, Hassan; Scriba, Thomas J; Tameris, Michele; Hughes, Jane; Hatherill, Mark; Day, Cheryl L; Hussey, Gregory D

    2012-03-02

    The vision of the South African Tuberculosis Vaccine Initiative (SATVI) (www.satvi.uct.ac.za) is 'A World Without TB' and our mission is 'Innovative and high-quality TB vaccine research in Africa, to impact the global epidemic'. Over the last 10 years, our focus has been twofold: first, clinical trials of BCG and of new candidate vaccines, and second, complementary research that addresses critical questions in TB vaccine development. SATVI is now widely regarded as the leading TB vaccine clinical research site in the world.

  19. Othering: difference understood??: a 10-year analysis and critique of the nursing literature.

    PubMed

    Canales, Mary K

    2010-01-01

    It has been 10 years since Advances in Nursing Science (ANS) published the first article that articulated othering within a nursing framework. This issue's topic, Critique and Replication, provided an opportunity for analysis of the influence of the original ANS article on the visibility and application of othering within nursing literature. Comprehensive searches of major health databases identified 32 publications citing the original ANS article. The analysis focused on exclusionary and inclusionary othering, role taking, and constructions of the other. Results indicate that although othering has become more visible within nursing literature, exclusionary othering dominates. The article concludes with thoughts for moving beyond othering and toward engagement.

  20. A case of choroidal osteoma in a 10-year-old child

    PubMed Central

    Behera, Madhusmita; Das, Manmath Kumar

    2015-01-01

    Choroidal osteoma is a rare, benign tumor, usually diagnosed in healthy adult women in their second or third decade of life. Though its etiology and pathogenesis are unclear, it is usually diagnosed due to its typical clinical features of yellowish-orange colored subretinal lesion at posterior pole and a dense echogenic plaque persisting even in lower gains on B-scan ultrasonography. Mostly unilateral (79%), the median age of diagnosis is 26 years. It is relatively rare in children. We report a case of choroidal osteoma in a 10-year-old boy. PMID:26586966

  1. Solitary fibrous tumor arising slowly in the vulva over 10 years: case report and review.

    PubMed

    Taki, Mana; Baba, Tsukasa; Mandai, Masaki; Suzuki, Ayako; Mikami, Yoshiki; Matsumura, Noriomi; Konishi, Ikuo

    2012-05-01

    Solitary fibrous tumor (SFT), which was first described as a pleural lesion by Klemperer and Rabin in 1931, is a rare, slow-growing neoplasm characterized by the proliferation of fibroblast-like spindle cells arranged in a patternless manner with few nuclear atypia. Extrathoracic SFT have increasingly been recognized, but those in the genital tract are extremely rare. Gynecological SFT behave as tumors with low malignant potential to recur, metastasize, or affect nearby organs resulting in infertility. We report a case of vulvar SFT slowly growing for 10 years, and propose a strategy for the diagnosis and treatment of gynecological SFT.

  2. Incontinentia Pigmenti; a Rare Multisystem Disorder: Case Report of a 10-Year-Old Girl

    PubMed Central

    Rafatjoo, Rezvan; Taghdisi Kashani, Amene

    2016-01-01

    Incontinentia pigmenti is a rare genodermatosis in which the skin involvement occurs in all patients. Additionally, other ectodermal tissues may be affected such as the central nervous system, eyes, hair, nails and teeth. The disease has an X-linked dominant inheritance pattern. But in our case, there was a mutation in the body cells due to incontinentia pigmenti. The dermatological findings occur in four successive phases. We report the case of a 10-year-old female presented cutaneous, dental and ophthalmic characteristic with 3 years follow-up. Dental anomalies such as hypodontia, peg-shaped anterior teeth, malformed primary and permanent teeth, and delayed eruption were seen in our patient.

  3. Peroral Endoscopic Myotomy for the Treatment of Achalasia in a 10-Year-Old Male Patient

    PubMed Central

    Filser, Jörg; Dick, Anke; Meyer, Thomas; Germer, Christoph-Thomas; von Rahden, Burkard H.A.

    2014-01-01

    Peroral endoscopic myotomy (POEM) is a new endoscopic treatment for achalasia with very good short-term results in adults. Data about POEM in pediatric patients are missing. We present the case of a 10-year-old male patient with type I (classic) achalasia, successfully treated with POEM. The procedure was accomplished in a similar fashion to the technique used in adults. Short-term results were fine, with a complete control of dysphagia and absence of reflux. We suggest that POEM is a suitable option in pediatric patients—similar to adults—but long-term results must be awaited. PMID:26171309

  4. Mycoplasma pneumoniae associated organising pneumonia in a 10 year old boy.

    PubMed

    Wachowski, O; Demirakça, S; Müller, K-M; Scheurlen, W

    2003-03-01

    We describe a 10 year old boy with organising pneumonia associated with acute Mycoplasma pneumoniae infection. The diagnosis of organising pneumonia was made by open lung biopsy and the M pneumoniae infection was proven serologically. Antibiotic and long term corticosteroid treatment resulted in steadily improving pulmonary function monitored by spirometry. The introduction of anti-inflammatory treatment with NSAIDs/immunosuppressive agents in order to spare steroids was well tolerated and resulted in further improvement of the pulmonary function. To our knowledge this is the first documented case of Mycoplasma pneumoniae associated organising pneumonia to be reported in a child.

  5. [Multicenter retrospective analysis of the patients with sarcoidosis with a 10 year interval in observations].

    PubMed

    Vizel', I Iu; Shmelev, E I; Baranova, O P; Barlamov, P N; Borodina, G L; Denisova, O A; Dobin, V L; Kulbaisov, A M; Kupaev, V I; Listopadova, M V; Ovsiannikov, N V; Os'kin, D N; Petrov, D V; Solov'ev, K I; Shul'zhenko, L V; Vizel', A A

    2014-01-01

    Comparison of the state of 83 patients with histologically confirmed sarcoidosis observed with a 10 year interval revealed remission in 47% of the cases. The main factors having negative effect on prognosis of the disease included extrapulmonary symptoms, the use ofcorticosteroids (at all stages, especially at stage I and in Lofgren syndrome) and antituberculosis drugs, positive TB test. Risk factors of relapses were stage II sarcoidosis, the use of systemic corticosteroids in patients with Lofgren syndrome and antituberculosis drugs, initially low FEV1/FVLC ratio and the number of lymphocytes in peripheral blood. PMID:25799827

  6. Photodynamic therapy for bronchial carcinoid tumours: complete response over a 10-year follow-up.

    PubMed

    Moghissi, Keyvan; Dixon, Kate; Gibbins, Sally

    2013-06-01

    A 63-year old woman diagnosed in September 2001 with a typical bronchial carcinoid of the left upper lobe bronchus extending into the left main stem bronchus is presented. The patient was unsuitable for standard surgical treatment, and the topography was not amenable for a parenchyma-saving bronchoplastic procedure. Two cycles of bronchoscopic photodynamic therapy (PDT) were undertaken at 6 monthly intervals. The patient has now been followed up regularly for over 10 years without signs of recurrence bronchoscopically or radiologically. To our knowledge, this is the first case of a carcinoid tumour treated solely by PDT. PMID:23284100

  7. Isolated intramedullary spinal cysticercosis in a 10-year-old female showing dramatic response with albendazole

    PubMed Central

    Azfar, Shah F.; Kirmani, Sanna; Badar, Farheen; Ahmad, Ibne

    2011-01-01

    Neurocysticercosis is the most common parasitic infection of the central nervous system caused by larvae of Taenia solium. Spinal cysticercosis is an uncommon site of cysticercal infection, and isolated intramedullary involvement is even rarer. We present a case of 10-year-old girl who presented with gradual onset paraparesis with sensory loss and bowel and bladder incontinence. Magnetic resonance imaging (MRI) of spine revealed a cystic lesion with mural nodule (scolex) which was diagnostic for cysticercosis. Patient was treated with antihelminthic, which led to marked clinico-radiological improvement. PMID:21977090

  8. The effects of fire severity on black carbon additions to forest soils - 10 years post fire

    NASA Astrophysics Data System (ADS)

    Poore, R.; Wessman, C. A.; Buma, B.

    2013-12-01

    horizon and the top 10cm mineral horizon. The soils were sieved to 2mm and their BC content measured using the Kurth-MacKenzie-DeLuca method of digesting labile carbon using nitric acid and hydrogen peroxide at 95C for 20hrs. We integrated both remotely sensed data and field observations. We used the Relative Difference Normalized Burn Ratio (RdNBR) calculated by Monitoring Trends in Burn Severity (MTBS). This index used Landsat images from July in the years before and after the fire and is based on differences in bands 4 and 7, with the aim of assessing coarse scale changes in soil and vegetation post fire. For each plot we also collected data on tree mortality and organic soil depth. These metrics were chosen from the Composite Burn Index as those that were most reliable even 10 years after the fire. We observed no significant differences in BC totals between high severity fire and unburned plots, although BC increased slightly on burned plots. Early results for low severity sites (analysis still in progress) suggest that BC increased in plots experiencing lower severity fires compared to unburned and high severity plots. Comparing carbon and BC totals on unburned and severely burned plots, and assuming no loss of BC from mineral soil during the fire, we observed a 1.2% conversion of burned biomass to BC, which corresponds with literature estimates of 1-4%.

  9. Postoperative epidural analgesia for patients undergoing pectus excavatum corrective surgery: a 10-year retrospective analysis

    PubMed Central

    Siddiqui, Asad; Tse, Andrew; Paul, James E; Fitzgerald, Peter; Teh, Bernice

    2016-01-01

    Introduction Managing postoperative pain in patients undergoing minimally invasive pectus excavatum repair (Nuss procedure) is challenging but essential in facilitating ambulation and minimizing the length of stay. Although multiple epidural regimens with varying opioids are presently used for pain management, there is currently no clinical consensus regarding which epidural regimen provides the best analgesia outcomes with the fewest side effects. This 10-year retrospective cohort study was performed to compare the quality of analgesia and the incidence of side effects associated with the three most common epidural regimens used at a tertiary care children’s hospital, in patients undergoing the Nuss procedure. Methods Seventy-two pediatric patients were identified as having been treated with one of three epidural regimens for postoperative pain management following the Nuss procedure: Group A (n=12) received 0.125% bupivacaine and 5 µg/mL fentanyl, Group B (n=21) received 0.125% bupivacaine and 10 µg/mL hydromorphone, and Group C (n=39) received 0.1% ropivacaine and 20 µg/mL hydromorphone. Our primary outcome was maximal daily pain scores (numerical rating scale 0–10), with an analytical focus on postoperative day 1 scores. The primary outcome was analyzed using linear regression. The secondary outcomes included the length of stay, side-effect profiles as reflected by the number of treatments for nausea and pruritus, pain scores according to epidural site insertion, occurrence of breakthrough pain, and presence of severe pain throughout their hospital stay. Secondary outcomes were analyzed using linear or logistic regression adjusted for pain scores at baseline. The criterion for statistical significance was set a priori at alpha =0.05. Results Group A had significantly higher day-1 pain scores (score 5.42/10) than Group B (4.52/10; P=0.030) and Group C (4.49/10; P=0.015) after adjusting for baseline pain and age. No significant difference in maximum daily

  10. 24 CFR 232.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Amortization period. (1) The loan shall have an amortization of either 5, 10, or 15 years by providing for... period in excess of 15 years unless the amount of the loan exceeds $50,000.00, in which event the amortization period may be increased to 20 years, with a provision for 240 monthly amortization payments....

  11. 24 CFR 232.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Amortization period. (1) The loan shall have an amortization of either 5, 10, or 15 years by providing for... period in excess of 15 years unless the amount of the loan exceeds $50,000.00, in which event the amortization period may be increased to 20 years, with a provision for 240 monthly amortization payments....

  12. 24 CFR 232.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Amortization period. (1) The loan shall have an amortization of either 5, 10, or 15 years by providing for... period in excess of 15 years unless the amount of the loan exceeds $50,000.00, in which event the amortization period may be increased to 20 years, with a provision for 240 monthly amortization payments....

  13. 24 CFR 232.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Amortization period. (1) The loan shall have an amortization of either 5, 10, or 15 years by providing for... period in excess of 15 years unless the amount of the loan exceeds $50,000.00, in which event the amortization period may be increased to 20 years, with a provision for 240 monthly amortization payments....

  14. 24 CFR 232.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Amortization period. (1) The loan shall have an amortization of either 5, 10, or 15 years by providing for... period in excess of 15 years unless the amount of the loan exceeds $50,000.00, in which event the amortization period may be increased to 20 years, with a provision for 240 monthly amortization payments....

  15. Accuracy of the Generalized Self-Consistent Method in Modelling the Elastic Behaviour of Periodic Composites

    NASA Technical Reports Server (NTRS)

    Walker, Kevin P.; Freed, Alan D.; Jordan, Eric H.

    1993-01-01

    Local stress and strain fields in the unit cell of an infinite, two-dimensional, periodic fibrous lattice have been determined by an integral equation approach. The effect of the fibres is assimilated to an infinite two-dimensional array of fictitious body forces in the matrix constituent phase of the unit cell. By subtracting a volume averaged strain polarization term from the integral equation we effectively embed a finite number of unit cells in a homogenized medium in which the overall stress and strain correspond to the volume averaged stress and strain of the constrained unit cell. This paper demonstrates that the zeroth term in the governing integral equation expansion, which embeds one unit cell in the homogenized medium, corresponds to the generalized self-consistent approximation. By comparing the zeroth term approximation with higher order approximations to the integral equation summation, both the accuracy of the generalized self-consistent composite model and the rate of convergence of the integral summation can be assessed. Two example composites are studied. For a tungsten/copper elastic fibrous composite the generalized self-consistent model is shown to provide accurate, effective, elastic moduli and local field representations. The local elastic transverse stress field within the representative volume element of the generalized self-consistent method is shown to be in error by much larger amounts for a composite with periodically distributed voids, but homogenization leads to a cancelling of errors, and the effective transverse Young's modulus of the voided composite is shown to be in error by only 23% at a void volume fraction of 75%.

  16. HIV-positive shopper who bit employee gets 10 years in jail.

    PubMed

    1996-05-31

    Judge John Goshgarian sentenced John [name removed] to 10 years in prison for biting a store employee and then declaring he was HIV-positive. An unidentified employee at the Sam's Club store in Gurnee, IL tried to block [name removed] from exiting during questioning about a check he had just written. The bite [name removed] made on the employee's arm left teeth marks and drew blood. [Name removed] was charged with criminal transmission of HIV, a charge rarely used. He pled guilty to a lesser offense-aggravated battery in a public way, as well as related charges of forgery, possession of a fictitious driver's license, and obstruction of justice. The judge sentenced [name removed] to the maximum of 10 years in prison on the battery charge; criminal transmission punishment is 3 to 7 years in prison. [Name removed]'s test results remain sealed, although the store employee has been notified of the results and is undergoing monthly testing for HIV antibodies. Thus far, the results show he does not have the virus.

  17. The EnviSAT ASAR Mission: A Look Back At 10 Years Of Operation

    NASA Astrophysics Data System (ADS)

    Miranda, N.; Rosich, B.; Meadows, P. J.; Haria, K.; Small, D.; Schubert, A.; Lavalle, M.; Collard, F.; Johnsen, H.; Guarnieri, A. Monti; D'Aria, D.

    2013-12-01

    The Advanced Synthetic Aperture Radar (ASAR) on- board Envisat operated successfully for just over 10 years until the failure of Envisat in April 2012. ASAR was ESA's very first deployment of a C-band phased- array antenna, allowing extended imaging capacity in comparison to its ERS SAR predecessors. As such it operated in various acquisition modes - Image (IM), Alternating Polarisation (AP), Wide Swath (WS), Global Monitoring (GM), and Wave (WV). For IM and AP modes there was a selection of 7 swaths with swath width from 100 km to 56 km: IM was single- polarisation, while AP was dual-pol, offering a choice from HH&VV, HH&HV, or VV&VH. WS and GM modes had a total swath width of 405 km based on the combination of 5 sub-swaths. WV acquired imagettes of 10 km by 10 km every 100 km along the satellite track. This paper is a look back to the 10 years of ASAR operations, covering topics such as the ASAR Instrument (characteristics, acquisition modes, product tree and observation scenario), Instrument Calibration and Performance Verification (including instrument stability, internal calibration, external calibration, absolute radiometric calibration, localisation accuracy, absolute geolocation accuracy, performance verification and product calibration), ASAR specific missions (wave and polarimetric), particular ASAR events such as antenna resets, burst synchronisation, AP swath modifications and the Envisat orbit change in October 2010.

  18. 10 Years of Height Resolved, Cloud-Track, Vector Winds from MISR

    NASA Astrophysics Data System (ADS)

    Garay, M. J.; Mueller, K. J.; Moroney, C. M.; Jovanovic, V.; Wu, D. L.; Diner, D. J.

    2009-12-01

    By utilizing multiple camera views and fast image matching algorithms to identify common features and determine feature motion, the MISR instrument on NASA’s Terra satellite has now collected nearly 10 years of height-resolved, cloud-track, vector winds using a single, globally consistent algorithm. The MISR cloud-track winds are reported globally on mesoscale domains of 70.4 km × 70.4 km and referenced to stereoscopically derived heights above the earth ellipsoid, which have a nominal vertical resolution of approximately 500 m. Importantly, from the standpoint of climate research, the stereo height assignment and wind retrieval are largely insensitive to instrument calibration changes because the pattern matcher relies only on relative brightness values, rather than the absolute magnitude of the brightness. We will describe comparisons with other wind datasets, including geostationary cloud drift winds, scatterometer surface winds, and reanalysis model winds, that demonstrate the quality of the MISR winds. We will also show the coverage and resolution advantages that MISR provides relative to these other datasets. Additionally, because the global winds are driven primarily by the global (im)balance of heating, monitoring variations in the winds over 10 years promises to yield important insights into the processes related to the hydrologic cycle and transport of heat and water vapor, such as the Madden-Julian Oscillation (MJO) and the El Niño Southern Oscillation (ENSO).

  19. Cementless total knee arthroplasty with Profix: a 8- to 10-year follow-up study.

    PubMed

    Hardeman, François; Vandenneucker, Hilde; Van Lauwe, Johan; Bellemans, Johan

    2006-12-01

    A consecutive series of 115 cementless Profix (Smith and Nephew, Memphis, USA) Total Knee Arthroplasties performed in 113 patients were followed in order to determine the functional results and survivorship at 8 to 10 years. All patients were included in a prospective database and were reviewed annually until final follow-up. Patients overall satisfaction was excellent or good in 91.3% of cases. The mean Knee Society's knee and function scores increased respectively from 49.3 and 36.7 preoperatively to 93.1 and 82.2 postoperatively. The Kaplan-Meier estimate of implant survival at 10 years was 97.1%. Two patients underwent revision and were considered as failures. One patient had a fracture of the medial condyle at 4 days post-surgery, and the other was revised for aseptic loosening of the tibial component at 6 years post-surgery. On the basis of this long-term follow-up study, we can conclude that the Profix Total Knee System is effective and safe. PMID:17064905

  20. Overview of Aqua MODIS 10-year On-orbit Calibration and Performance

    NASA Technical Reports Server (NTRS)

    Xiong, X.; Wenny, B.; Sun, J.; Wu, A.; Chen, H.; Angal, A.; Choi, T.; Madhavan, S.; Geng, X.; Link, D.; Toller, G.; Barnes, W.; Salomonson, V.

    2012-01-01

    Since launch in May 2002, Aqua MODIS has successfully operated for nearly 10 years, continuously collecting global datasets for scientific studies of key parameters of the earth's land, ocean, and atmospheric properties and their changes over time. The quality of these geophysical parameters relies on the input quality of sensor calibrated radiances. MODIS observations are made in 36 spectral bands with wavelengths ranging from visible (VIS) to longwave infrared (LWIR). Its reflective solar bands (RSB) are calibrated using data collected from its on-board solar diffuser and regularly scheduled lunar views. The thermal emissive bands (TEB) are calibrated using an on-board blackbody (BB). The changes in the sensor's spectral and spatial characteristics are monitored by an on-board spectroradiometric calibration assembly (SRCA). This paper presents an overview of Aqua MODIS 10-year on-orbit operation and calibration activities, from launch to present, and summarizes its on-orbit radiometric, spectral, and spatial calibration and characterization performance. In addition, it will illustrate and discuss on-orbit changes in sensor characteristics and corrections applied to continuously maintain the sensor level 1B (L1B) data quality, as well as lessons learned that could benefit future calibration efforts.

  1. Highlights from 10 Years of NASA/KNMI/FMI Collaboration on UV Remote Sensing from Space

    NASA Technical Reports Server (NTRS)

    Bhartia, Pawan K.

    2010-01-01

    The first joint meeting between NASA, KNMI and FMI scientists was held on 13 & 14 June, 2000, almost exactly 10 years ago. NASA had recently selected 14 US scientists to work on instrument calibration, science algorithms, and validation activities related to the Ozone Monitoring Instrument (OMI) that we being built by collaboration between the Netherlands and Finland for flight on NASA's EOS Aura satellite. The progress on this project had been remarkable for a space based instrument. Only two years before this meeting my colleague Ernest Hilsenrath and I had visited Netherlands at the invitation of Fokker Space to persuade KNMI management to collaborate with NASA on this mission. And only 4 years after the first science meeting was held OMI was lunched on the Aura spacecraft. Next month will be the 6 th anniversary of this launch and very successful operation of OMI. All this was possible because of the leadership from Dr. Hennie Kelder and KNMI management who in 1998 saw the opportunity for Netherlands in the mission and stepped up to the challenge by creating a young and talented team of scientists at KNMI under the leadership of Dr. Pieterenel Levelt. This vision has now put Netherlands as the leading country in the world in monitoring air quality from space. Recent selection of TROPOMI by ESA attests to the success of this vision. I will present some selected highlights of our very successful collaboration on this project over the past 10 years.

  2. Prenatal alcohol and marijuana exposure: effects on neuropsychological outcomes at 10 years.

    PubMed

    Richardson, Gale A; Ryan, Christopher; Willford, Jennifer; Day, Nancy L; Goldschmidt, Lidush

    2002-01-01

    This report from a longitudinal study of the effects of prenatal alcohol and marijuana exposure investigates whether these drugs affect neuropsychological development at 10 years of age. Women were recruited from a medical assistance prenatal clinic and interviewed about their substance use at the end of each trimester of pregnancy, at 8 and 18 months, and at 3, 6, 10, 14, and 16 years. Half of the women were African American, and half were Caucasian. The women were generally from lower socioeconomic status families and had obtained high school degrees. At the 10-year follow-up, 593 children completed a neuropsychological battery, which focused on problem solving, learning and memory, mental flexibility, psychomotor speed, attention, and impulsivity. Prenatal alcohol use was found to have a significant negative impact on learning and memory skills, as measured by the WRAML. Prenatal marijuana exposure also had an effect on learning and memory, as well as on impulsivity, as measured by a continuous performance task. The effects of prenatal alcohol and marijuana exposure persisted when other predictors of learning and memory were controlled. We continue to follow these offspring into the adolescent years when further neuropsychological deficits may become evident.

  3. Estimation of the Unextendable Dead Time Period in a Flow of Physical Events by the Method of Maximum Likelihood

    NASA Astrophysics Data System (ADS)

    Nezhel'skaya, L. A.

    2016-09-01

    A flow of physical events (photons, electrons, and other elementary particles) is studied. One of the mathematical models of such flows is the modulated MAP flow of events circulating under conditions of unextendable dead time period. It is assumed that the dead time period is an unknown fixed value. The problem of estimation of the dead time period from observations of arrival times of events is solved by the method of maximum likelihood.

  4. Crowd-out 10 years later: have recent public insurance expansions crowded out private health insurance?

    PubMed

    Gruber, Jonathan; Simon, Kosali

    2008-03-01

    Ten years ago, Cutler and Gruber [Cutler, D., Gruber, J., 1996. Does public health insurance crowdout private insurance? Quarterly Journal of Economics 111, 391-430] suggested that crowd-out might be quite large, but much subsequent research has questioned this conclusion. Our results using improved data and methods clearly show that crowd-out is still significant in the 1996-2002 period. This finding emerges most strongly when we consider family level measures of public insurance eligibility. We also find that recent anti-crowd-out provisions in public expansions may have had the opposite effect, lowering take-up by the uninsured faster than they lower crowd-out of private insurance.

  5. Cold start extra emissions as a function of engine stop time: Evolution over the last 10 years

    NASA Astrophysics Data System (ADS)

    Favez, Jean-Yves; Weilenmann, Martin; Stilli, Jan

    Cars with catalysts show a significant increase in exhaust emissions at engine start. These extra emissions are expressed as the difference, over a particular driving cycle, between emissions generated when the vehicle is started and when the engine or the catalyst are stably warm. Experimental data, suitable for the assessment of cold start emissions, are usually available for completely cooled engines. Most results originate from tests at ambient temperature of 20-30 °C and with an engine stop time of at least 12 h. On the other hand, data including shorter stop times are very rare. The present work investigates the influence of exhaust emissions with shorter stop times, i.e. 0.5, 1, 2 and 4 h. The main goal consists in the comparison of emissions exhausted by recent car models (Euro-4) against emissions assessed in the framework of a similar campaign 10 years ago (FAV1/Euro-1 vehicles). A short survey of the current extra emission estimation methods is presented in this paper. It is shown that some methods are not suited for providing correct estimations in all cases. We discuss the fact that different estimation methods can show either similar or completely different results depending on the evolution behaviour of the hot emissions. Due to new technologies, e.g. the catalyst and improved engine control algorithms, emissions have been considerably reduced over the last 10 years. In this study it is determined how the relative extra emissions, i.e. extra emissions relative to the extra emissions for the standard stop time of 12 h, expressed as a function of stop time have changed. We may claim with caution that for medium stop times of 0.5-4 h the average relative extra emissions of Euro-4 vehicles are well below the average of the relative extra emissions of Euro-1 vehicles.

  6. Tropospheric Nitrogen Dioxide Column Density Trends Seen from the 10-year Record of OMI Measurements over East Asia

    NASA Astrophysics Data System (ADS)

    Irie, H.; Muto, T.; Itahashi, S.; Kurokawa, J. I.

    2015-12-01

    The Ozone Monitoring Instrument (OMI) aboard the Aura satellite recorded the 10-year (2005-2014) of tropospheric nitrogen dioxide (NO2) vertical column density (VCD) data. The data set taken over East Asia was analyzed to estimate linear trends on national and grid bases for two periods of 2005-2011 and 2011-2014. The most striking features are leveling-off or decreasing trends seen in NO2 VCDs over China for 2011-2014 after continuous increases for 2005-2011. In particular, a significant reduction by ~14% occurred from 2013 through 2014, attaining to the level of 2009. The grid-basis trend analysis implies that the turnaround seen in the trends occurred on a province or larger spatial scale and was likely due mainly to the technical improvement such as the widespread use of de-NOx units. Another prominent features are seen in Japan, where NO2 VCDs decreased at a rate of ~4% per year from 2005 to 2011. The rate was almost unchanged between the two periods 2005-2011 and 2011-2014, while the significant power substitution of thermal power generation for the nuclear power generation took place in Japan after 2011, when a massive earthquake occurred off the Pacific coast of northern Japan. This reflects a less contribution of NOx emissions from the power plant sector than that from the transport sector in the Pacific Belt Zone lying over metropolitan areas.

  7. Rosetta begins its 10-year journey to the origins of the Solar System

    NASA Astrophysics Data System (ADS)

    2004-03-01

    Rosetta’s mission began at 08h17 CET (07h17 GMT) on 2 March when a European Ariane 5 launch vehicle liftered off from the Guiana Space Centre, Europe’s spaceport in Kourou, French Guiana. The launcher successfully placed its upper stage and payload into an eccentric coast orbit (200 x 4000 km). About two hours later, at 10h14 CET (09h14 GMT) the upper stage ignited its own engine to reach an escape velocity in order to leave the Earth’s gravity field and enter heliocentric orbit. The Rosetta probe was released about 18 minutes later. “After the recent success of Mars Express, Europe is now heading to deep space with another fantastic mission. We will have to be patient, as the rendezvous with the comet will not take place until ten years from now, but I think it’s worth the wait” said ESA’s Director General Jean-Jacques Dordain witnessing the launch from Kourou. ESA’s Operations Centre (ESOC) in Darmstadt, Germany, has established contact with the probe as it flies away from Earth at a relative speed of about 3.4 km/s. ESOC will be in charge of Rosetta operations and orbit determination throughout the mission. During the next eight months, the spacecraft’s onboard systems will be checked and its science payload will be commissioned. A 10-year odyssey Rosetta will be reactivated for planetary flybys, which will be used to modify its trajectory through gravity assist manoeuvres. During the trip, the probe could also observe one or more asteroids, observation of asteroids being one of the mission's secondary objectives. The first planetary encounter will be in March 2005, as Rosetta flies by the Earth for the first time. The gravity assist will boost Rosetta into an orbit that will take it to Mars two years later. During its close encounter with Mars in February 2007, Rosetta will approach to a distance of about 200 km and conduct science observations. This Martian flyby will be followed by another Earth flyby in November the same year. Both

  8. A Simple yet Accurate Method for Students to Determine Asteroid Rotation Periods from Fragmented Light Curve Data

    ERIC Educational Resources Information Center

    Beare, R. A.

    2008-01-01

    Professional astronomers use specialized software not normally available to students to determine the rotation periods of asteroids from fragmented light curve data. This paper describes a simple yet accurate method based on Microsoft Excel[R] that enables students to find periods in asteroid light curve and other discontinuous time series data of…

  9. Numerical quadrature methods for integrals of singular periodic functions and their application to singular and weakly singular integral equations

    NASA Technical Reports Server (NTRS)

    Sidi, A.; Israeli, M.

    1986-01-01

    High accuracy numerical quadrature methods for integrals of singular periodic functions are proposed. These methods are based on the appropriate Euler-Maclaurin expansions of trapezoidal rule approximations and their extrapolations. They are used to obtain accurate quadrature methods for the solution of singular and weakly singular Fredholm integral equations. Such periodic equations are used in the solution of planar elliptic boundary value problems, elasticity, potential theory, conformal mapping, boundary element methods, free surface flows, etc. The use of the quadrature methods is demonstrated with numerical examples.

  10. Acoustic anechoic layers with singly periodic array of scatterers: Computational methods, absorption mechanisms, and optimal design

    NASA Astrophysics Data System (ADS)

    Yang, Hai-Bin; Li, Yue; Zhao, Hong-Gang; Wen, Ji-Hong; Wen, Xi-Sen

    2014-10-01

    The acoustic properties of anechoic layers with a singly periodic array of cylindrical scatterers are investigated. A method combined plane wave expansion and finite element analysis is extended for out-of-plane incidence. The reflection characteristics of the anechoic layers with cavities and locally resonant scatterers are discussed. The backing is a steel plate followed by an air half space. Under this approximate zero transmission backing condition, the reflection reduction is induced by the absorption enhancement. The absorption mechanism is explained by the scattering/absorption cross section of the isolated scatterer. Three types of resonant modes which can induce efficient absorption are revealed. Due to the fact that the frequencies of the resonant modes are related to the size of the scatterers, anechoic layers with scatterers of mixed size can broaden the absorption band. A genetic optimization algorithm is adopted to design the anechoic layer with scatterers of mixed size at a desired frequency band from 2 kHz to 10 kHz for normal incidence, and the influence of the incident angle is also discussed.

  11. An autocorrelation method to detect periodic gravitational waves from neutron stars in binary systems

    NASA Astrophysics Data System (ADS)

    Viceré, Andrea; Yvert, Michel

    2016-08-01

    Rotating, non-axisymmetric neutron stars are expected to emit continuous gravitational waves at a nearly stable frequency. Nowadays about 2500 pulsars have been detected, thanks to their beamed electromagnetic emission, and many more of these objects should exist, whose electromagnetic beam does not include Earth and cannot be detected. The gravitational emission is not beamed, and could be accessible to gravitational observatories, even though no detection as been claimed yet. About half of the pulsars predicted to possibly emit gravitational waves in the frequency range accessible to ground-based interferometers belongs to binary systems; this is an additional complication, because the frequencies of these pulsars are Doppler-shifted due to their orbital motion, and an optimal detection strategy would require a computing power far beyond the present capabilities. We present here an approach which allows searching all-sky for such sources, over a broad range of frequencies, orbital periods and binary system eccentricities, reaching sensitivities potentially good enough to provide candidates for more sophisticated hierarchical detection methods. We test this new technique using real data taken during the first science run of Virgo, and estimating the sensitivity to a set of simulated pulsar signals.

  12. Proposed method for measurement of flow rate in turbulent periodic pipe flow

    NASA Astrophysics Data System (ADS)

    Werzner, E.; Ray, S.; Trimis, D.

    2011-12-01

    The present investigation deals with a previously proposed flow metering technique for laminar, fully-developed, time-periodic pipe flow. Employing knowledge of the pulsation frequency-dependent relationship between the mass flow rate and the pressure gradient, the method allows reconstruction of the instantaneous mass flow rate on the basis of a recorded pressure gradient time series. In order to explore if the procedure can be extended for turbulent flows, numerical simulations for turbulent, fully-developed, sinusoidally pulsating pipe flow with low pulse amplitude have been carried out using a ν2-f turbulence model. The study covers pulsation frequencies, ranging from the quasi-steady up to the inertia-dominated frequency regime, and three cycle-averaged Reynolds numbers of 4360, 9750 and 15400. After providing the theoretical background of the flow rate reconstruction principle, the numerical model and an experimental facility for the verification of simulations are explained. The obtained results, presented in time and frequency domain, show good agreement with each other and indicate a frequency dependence, similar to that used for the signal reconstruction for laminar flows. A modified dimensionless frequency definition has been introduced, which allows a generalised representation of the results considering the influence of Reynolds number.

  13. Comparison of Columnar Water Vapor Measurements During The Fall 1997 ARM Intensive Observation Period: Optical Methods

    NASA Technical Reports Server (NTRS)

    Schmid, Beat; Michalsky, J.; Slater, D.; Barnard, J.; Halthore, R.; Liljegren, J.; Holben, B.; Eck, T.; Livingston, J.; Russell, P.; Hipskind, R. Stephen (Technical Monitor)

    2000-01-01

    In the fall of 1997 the Atmospheric Radiation Measurement (ARM program conducted an intensive Observation Period (IOP) to study water vapor at its Southern Great Plains (SGP) site. Among the large number of instruments, four sun-tracking radiometers were present to measure the columnar water vapor (CWV). All four solar radiometers retrieve CWV by measuring solar transmittance in the 0.94-micrometer water vapor absorption band. As one of the steps in the CWV retrievals the aerosol component is subtracted from the total transmittance, in the 0.94-micrometer band. The aerosol optical depth comparisons among the same four radiometers are presented elsewhere. We have used three different methods to retrieve CWV. Without attempting to standardize on the same radiative transfer model and its underlying water vapor spectroscopy we found the CWV to agree within 0.13 cm (rms) for CWV values ranging from 1 to 5 cm. Preliminary results obtained when using the same updated radiative transfer model with updated spectroscopy for all instruments will also be shown. Comparisons to the microwave radiometer results will be included in the comparisons.

  14. Active Ingredients of Treatment and Client Mechanisms of Change in Behavioral Treatments for Alcohol Use Disorders: Progress 10 Years Later

    PubMed Central

    Magill, M.; Kiluk, B.D.; McCrady, B.; Tonigan, J.S.; Longabaugh, R.

    2015-01-01

    Background The current review revisits the article entitled: Active Ingredients of Behavioral Treatments for Alcohol Use Disorders (AUDs) published in Alcoholism: Clinical and Experimental Research. This work summarized proceedings from a 2004 Symposium of the same name that was held at the Annual Meeting of the Research Society on Alcoholism (RSA). A decade has passed, which provides occasion for an evaluation of progress. In 2014, an RSA symposium titled Active Treatment Ingredients and Client Mechanisms of Change in Behavioral Treatments for Alcohol Use Disorders: Progress 10 Years Later did just that. Overview The current review revisits state-of-the-art research on the three treatments examined 10 years ago: Cognitive Behavioral Therapy (CBT), Alcohol Behavior Couples Therapy (ABCT), and Twelve Step Facilitation (TSF). Because of its empirically-validated effectiveness and robust research agenda on the study of process-outcome, Motivational Interviewing (MI) has been selected as the fourth treatment modality to be discussed. For each of these four treatments, the reviewers provide a critical assessment of current theory and research with a special emphasis on key recommendations for the future. Conclusions Noteworthy progress has been made in identifying AITs and MOBCs in these four behavioral interventions for alcohol and other drug use disorders. Not only have we established some of the mechanisms through which these evidence-based treatments work, but we have also uncovered some of the limitations in our existing frameworks and methods. Further progress in this area will require a broader view with respect to conceptual frameworks, analytic methods, and measurement instrumentation. PMID:26344200

  15. Effects of background and classroom characteristics on the science achievement of 10-year-old students

    NASA Astrophysics Data System (ADS)

    Rosier, Malcolm

    1990-01-01

    Effects of characteristics of science classrooms on the science achievement of students were examined in the context of a simple model. The model incorporated prior attributes of the students in terms of home background, sex, and verbal and quantitative ability. The model was estimated by means of partial least squares multivariate procedures using data for 10-year-old Queensland students from the Second International Science Study. The results demonstrated the dominant influence of home background and verbal/mathematical ability. Female students tended to have lower scores after allowing for the influence of the other variables in the model. Students who stated that there were more student initiated activities in their science lessons tended to have lower achievement.

  16. Incontinentia Pigmenti; a Rare Multisystem Disorder: Case Report of a 10-Year-Old Girl

    PubMed Central

    Rafatjoo, Rezvan; Taghdisi Kashani, Amene

    2016-01-01

    Incontinentia pigmenti is a rare genodermatosis in which the skin involvement occurs in all patients. Additionally, other ectodermal tissues may be affected such as the central nervous system, eyes, hair, nails and teeth. The disease has an X-linked dominant inheritance pattern. But in our case, there was a mutation in the body cells due to incontinentia pigmenti. The dermatological findings occur in four successive phases. We report the case of a 10-year-old female presented cutaneous, dental and ophthalmic characteristic with 3 years follow-up. Dental anomalies such as hypodontia, peg-shaped anterior teeth, malformed primary and permanent teeth, and delayed eruption were seen in our patient. PMID:27602400

  17. Incontinentia Pigmenti; a Rare Multisystem Disorder: Case Report of a 10-Year-Old Girl.

    PubMed

    Rafatjoo, Rezvan; Taghdisi Kashani, Amene

    2016-09-01

    Incontinentia pigmenti is a rare genodermatosis in which the skin involvement occurs in all patients. Additionally, other ectodermal tissues may be affected such as the central nervous system, eyes, hair, nails and teeth. The disease has an X-linked dominant inheritance pattern. But in our case, there was a mutation in the body cells due to incontinentia pigmenti. The dermatological findings occur in four successive phases. We report the case of a 10-year-old female presented cutaneous, dental and ophthalmic characteristic with 3 years follow-up. Dental anomalies such as hypodontia, peg-shaped anterior teeth, malformed primary and permanent teeth, and delayed eruption were seen in our patient. PMID:27602400

  18. [Association between Crohn's disease and primary sclerosing cholangitis in a 10 year old girl].

    PubMed

    Muñoz Lozón, Ana; Iglesias Blázquez, Cristina; Menéndez Arias, Cristina; Domínguez Sánchez, Patricia

    2016-06-01

    A 10 year old girl with diarrhea, abdominal pain, weight loss and fever of one month and a half of evolution. Analytical and sonographic findings raised the possibility of inflammatory bowel disease. Endoscopy and histology showed findings consistent with Crohn's disease. Treatment was initiated with mesalazine and exclusive enteral nutrition. Later corticosteroid treatment, immunosuppressive drugs and ursodeoxycholic acid were added due to cholestasis and persistent hypergammaglobulinemia. Magnetic resonance cholangiography and liver biopsy confirmed the diagnosis of concomitant primary sclerosing cholangitis. The association between Crohn's disease and primary sclerosing cholangitis is rare, predominantly in males between 20 and 40 years old and it presents a great clinical variability. The confirmation of the diagnosis requires magnetic resonance cholangiography or endoscopic retrograde cholangiopancreatography. The prognosis is poor and there is no treatment to slow the progression of the disease.

  19. The genetic and environmental etiology of high math performance in 10-year-old twins.

    PubMed

    Petrill, Stephen A; Kovas, Yulia; Hart, Sara A; Thompson, Lee A; Plomin, Robert

    2009-07-01

    The genetic and environmental etiology of high math performance (at or above the 85%tile) was examined in a population-based sample of 10-year-old twins (nMZ = 1,279, nDZ = 2,305). Math skills were assessed using a web-based battery of math performance tapping skills related to the UK National Math Curriculum. Probandwise concordance rates and liability threshold models indicated that genetic and shared environmental influences were significant, and that these estimates were generally similar to those obtained across the normal range of ability and did not vary significantly by gender. These results suggest that the genetic and environmental influences at the high end of ability are likely to be continuous with those that affect the entire range of math performance across all children irrespective of gender.

  20. Perceived neighborhood safety, recovery capital, and successful outcomes among mothers 10 years after substance abuse treatment

    PubMed Central

    Evans, E.; Li, L.; Buoncristiani, S.; Hser, Y.I.

    2014-01-01

    This study examines perceived neighborhood characteristics associated with successful outcome among mothers 10 years after being treated for substance use disorders. Data were obtained from 713 mothers first studied at admission to drug treatment in California in 2000-2002 and followed-up in 2009-2011. At follow-up, 53.6% of mothers had a successful outcome (i.e., no use of illicit drugs and not involved with the criminal justice system). Perceived neighborhood safety almost doubled the odds of success. Perceived neighborhood safety interacted with social involvement, decreasing the odds of success among mothers who reported more versus less neighborhood social involvement. Perceived neighborhood climate is associated with long-term outcomes among mothers with substance use disorders independent of individual-level characteristics, underscoring the need for further efforts to understand its interaction with recovery capital in ways that promote and impede health. PMID:24832914

  1. A review of Internet pornography use research: methodology and content from the past 10 years.

    PubMed

    Short, Mary B; Black, Lora; Smith, Angela H; Wetterneck, Chad T; Wells, Daryl E

    2012-01-01

    Internet pornography (IP) use has increased over the past 10 years. The effects of IP use are widespread and are both negative (e.g., relationship and interpersonal distress) and positive (e.g., increases in sexual knowledge and attitudes toward sex). Given the possible negative effects of IP use, understanding the definition of IP, the types of IP used, and reasons for IP use is important. The present study reviews the methodology and content of available literature regarding IP use in nondeviant adult populations. The study seeks to determine how the studies defined IP, utilized validated measures of pornography use, examined variables related to IP, and addressed form and function of IP use. Overall, studies were inconsistent in their definitions of IP, measurement, and their assessment of the form and function of IP use. Discussion regarding how methodological differences between studies may impact the results and the ability to generalize findings is provided, and suggestions for future studies are offered. PMID:22032795

  2. Organic anti-corrosion systems in FGD lignite-fired units -- 10 years of operation experience

    SciTech Connect

    Schwart, G.; Moellmann, A.

    1998-07-01

    In order to meet the limitation of sulfur dioxide emission that came into force at the 1st July 1988 RWE Energie installed 37 flue gas desulfurizing plants (FGD) in 4 lignite fired stations. These FGD's are operated on basis of the limestone process. The types of scrubber are different. To protect the inner steel surfaces of the scrubbers and the ducts from corrosion by the flue gas and the condensate, rubbers and coatings are used. During 10 years of operation experience with FGD's several types of corrosion protection systems in the surface in the scrubber and the ducts were used. The reliability and break down mechanism of different types of soft rubber linings and resin systems is discussed.

  3. Evolution of Science Operations after 10 years of the Mars Express Mission

    NASA Astrophysics Data System (ADS)

    Cardesin Moinelo, Alejandro; Martin, Patrick

    2013-10-01

    The Mars Express mission was launched in June 2003 and has been providing great amounts of data since its arrival to Mars in Christmas 2003, covering a wide range of science objectives at all levels, from the surface and sub-surface geology, atmosphere dynamics and composition, up to the interaction with the magnetosphere and the characterization of the Martian sytem including its two moons, Phobos and Deimos. In these last 10 years, the Mars Express Science Operations Center has been responsible for the coordination of the scientific requirements and the implementation of the science plan, aiming to obtain the maximum scientific return of the mission while respecting the operational constraints. In this contribution we will show some of the operational challenges of the mission, focusing on the improvements and adaptations of the past years, not only in terms of technical and scientific requirements which have been varying with time, but also the optimization of the interfaces with all the teams involved.

  4. Voice disorders without organic diseases of the larynx. A 10-year review of 62 patients.

    PubMed

    Watanabe, Y; Miura, M; Shoji, H

    1983-01-01

    We reviewed the clinical records of 62 patients with voice disorders without organic diseases of the larynx who were examined in the Department of Otolaryngology, Kurume University Hospital during the 10 years from 1971 to 1980. There were 9 patients with psychogenic dysphonia, 24 with vocal abuse, 4 with spastic dysphonia, 9 with mutational voice disturbance, 8 with virilization of voice, 7 with dysphonia attributed to diseases of other organs than the larynx, and 1 with senile change of voice. The clinical service to the patients with these kinds of dysphonia has been poor in Japan for lack of trained voice pathologists. This has been also the case with our department. Recognition for the necessity of voice pathologists is strongly demanded.

  5. Pertussis Accompanying Recent Mycoplasma Infection in a 10-Year-Old Girl.

    PubMed

    Cheon, Mi Kyung; Na, Hyunju; Han, Seung Beom; Kwon, Hyo Jin; Chun, Yoon Hong; Kang, Jin Han

    2015-09-01

    Recently, the incidence of pertussis has been increasing; however, reports on mixed infection of pertussis with other respiratory pathogens are rare in highly immunized populations. We report the case of a 10-year-old girl who presented with cough, post-tussive emesis, and fever. She was subsequently diagnosed with bronchopneumonia. Although she had received five doses of diphtheria-tetanus-acellular pertussis vaccine, polymerase chain reaction of her nasopharyngeal aspirate confirmed Bordetella pertussis infection. In addition, serologic testing for Mycoplasma pneumoniae was also positive. The patient was treated with roxithromycin without any complications. This is the first report of mixed B. pertussis and M. pneumoniae infection in Korea. To avoid under-diagnosis, pertussis should be considered in patients with chronic cough even when other respiratory pathogens have been documented. PMID:26483996

  6. Tuskegee Bioethics Center 10th anniversary presentation: "Commemorating 10 years: ethical perspectives on origin and destiny".

    PubMed

    Prograis, Lawrence J

    2010-08-01

    More than 70 years have passed since the beginning of the Public Health Service syphilis study in Tuskegee, Alabama, and it has been over a decade since President Bill Clinton formally apologized for it and held a ceremony for the Tuskegee study participants. The official launching of the Tuskegee University National Center for Bioethics in Research and Health Care took place two years after President Clinton's apology. How might we fittingly discuss the Center's 10th Anniversary and the topic 'Commemorating 10 Years: Ethical Perspectives on Origin and Destiny'? Over a decade ago, a series of writers, many of them African Americans, wrote a text entitled 'African-American Perspectives on Biomedical Ethics'; their text was partly responsible for a prolonged reflection by others to produce a subsequent work, 'African American Bioethics: Culture, Race and Identity'. What is the relationship between the discipline of bioethics and African American culture? This and related questions are explored in this commentary.

  7. A 10-year plan to study the aquifer system of Indian Wells Valley, California

    USGS Publications Warehouse

    Lipinski, Paul; Knochenmus, Darwin D.

    1981-01-01

    Water needs of the population of Indian Wells Valley, Calif., must be met through further development of ground-water resources. Studies show that annual ground-water pumpage there has increased since 1945 and has exceeded mean annual recharge since 1966. Continued and increased stress on the aquifer system of the valley is expected because population in the valley is predicted to double by 1998 and triple by 2020, based on 1977 population figures. The U.S. Geological Survey proposes a 10-year program to develop a data base to aid in evaluation of future water-management alternatives. A study plan has been developed that describes present and potential problems and objectives of the program, and outlines work items to be undertaken in the study area. (USGS)

  8. Inflammation in end-stage renal disease--what have we learned in 10 years?

    PubMed

    Carrero, Juan J; Stenvinkel, Peter

    2010-01-01

    The first reports connecting uremic inflammation with a wasted and atherogenic phenotype and poor outcome initiated in the late 1990s. Since then, about 3500 publications appear on Medline, reflecting the exponential interest that this topic has evoked in nephrology. What was described as a "novel" risk factor 10 years ago has now evolved into an established finding in patients with end-stage renal disease (ESRD). The purpose of this review is to summarize the main advances contributing to our current understanding of the complex inflammatory processes present in ESRD. Causes and consequences of inflammation, genetic heritability of the inflammatory response, implications on outcome prognostication, and contemporary therapeutic evidence are some of the various topics discussed.

  9. [10 years after Chernobyl--radioactivity of mother's milk-- measurements from Tirol, Tibet and Nepal].

    PubMed

    Lechner, W; Brunner, P; Bergant, A; Pastner, E; Müller, D

    1997-11-28

    10 years after the Chernobyl disaster gamma radioactivity from Cs-137 was determined in 53 breast milk samples from Tyrol, as well as 9 samples from Tibet and 2 from Nepal by means of a gamma-spectrometer with a germanium detector. In contrast to the values obtained within a few days, and again 1 year after the nuclear plant catastrophe, all samples from Tyrol showed gamma radioactivity levels (median 0.07 nCi/l; range 0.02-0.20 nCi/l) which were now below the limit laid down for baby food in Austria (0.3 nCi/l-11.1 Bq). The samples from Tibet and Nepal registered a slightly higher level of gamma radioactivity (median 0.16 nCi/l; range 0.16-0.41 nCi/l).

  10. A review of Internet pornography use research: methodology and content from the past 10 years.

    PubMed

    Short, Mary B; Black, Lora; Smith, Angela H; Wetterneck, Chad T; Wells, Daryl E

    2012-01-01

    Internet pornography (IP) use has increased over the past 10 years. The effects of IP use are widespread and are both negative (e.g., relationship and interpersonal distress) and positive (e.g., increases in sexual knowledge and attitudes toward sex). Given the possible negative effects of IP use, understanding the definition of IP, the types of IP used, and reasons for IP use is important. The present study reviews the methodology and content of available literature regarding IP use in nondeviant adult populations. The study seeks to determine how the studies defined IP, utilized validated measures of pornography use, examined variables related to IP, and addressed form and function of IP use. Overall, studies were inconsistent in their definitions of IP, measurement, and their assessment of the form and function of IP use. Discussion regarding how methodological differences between studies may impact the results and the ability to generalize findings is provided, and suggestions for future studies are offered.

  11. Minimum 10-Year Wear Analysis of Highly Cross-Linked Polyethylene in Cementless Total Hip Arthroplasty.

    PubMed

    So, Kazutaka; Goto, Koji; Kuroda, Yutaka; Matsuda, Shuichi

    2015-12-01

    Fifty-four patients (64 hips) underwent cementless total hip arthroplasty between 2000 and 2003 with a 22-mm zirconia ceramic bearing on highly cross-linked polyethylene, and were evaluated with a mean 11.9-year postoperative follow-up (range, 10-14 years). Linear wear was measured on the anteroposterior radiograph of the hip. No evidence of osteolysis and loosening was found on the final radiograph in any of the cases, and the steady-state linear wear rate was 0.017±0.018 mm/year. No significant correlation was found between the linear wear rate and age, body weight, cup inclination angle, or polyethylene thickness. Highly cross-linked polyethylene showed excellent wear resistance for >10 years when used in combination with 22-mm zirconia heads.

  12. Total knee arthroplasty using cementless keels and cemented tibial trays: 10-year results

    PubMed Central

    Kolisek, Frank R.; Mont, Michael A.; Seyler, Thorsten M.; Marker, David R.; Jessup, Nenette M.; Siddiqui, Junaed A.; Monesmith, Eric

    2008-01-01

    The problem of early mechanical stability of cemented and cementless keels of the tibial component in total knee arthroplasty (TKA) is controversial. The purpose of this study was to assess clinical and radiographic outcomes of a cohort of 51 TKAs using a cemented platform with cementless keel fixation. At a mean follow-up of 10.4 years (range, 7 to 14 years), the mean Knee Society Score (KSS) was 93 points (range, 59 to 100 points), and the mean functional score was 73 points (range, 0 to 100 points). Only one patient demonstrated progressive tibial radiolucencies at 13.1 years follow-up, which resolved with a revision with an exchange of components. The results of this study suggest that a proximally cemented tibial tray with a press-fit keel TKA provides excellent mean 10-year outcomes. PMID:18185931

  13. The World Health Organization European Health in Prisons Project After 10 Years: Persistent Barriers and Achievements

    PubMed Central

    Gatherer, Alex; Moller, Lars; Hayton, Paul

    2005-01-01

    The recognition that good prison health is important to general public health has led 28 countries in the European Region of the World Health Organization (WHO) to join a WHO network dedicated to improving health within prisons. Within the 10 years since that time, vital actions have been taken and important policy documents have been produced. A key factor in making progress is breaking down the isolation of prison health services and bringing them into closer collaboration with the country’s public health services. However, barriers to progress remain. A continuing challenge is how best to move from policy recommendations to implementation, so that the network’s fundamental aim of noticeable improvements in the health and care of prisoners is further achieved. PMID:16186449

  14. After more than 10 years of Gulf War veteran medical evaluations, what have we learned?

    PubMed

    Gray, Gregory C; Gackstetter, Gary D; Kang, Han K; Graham, John T; Scott, Ken C

    2004-06-01

    Since the 1991 Gulf War, more than 10 years and 1 billion dollars of health evaluations and research have been invested in understanding illnesses among Gulf War veterans. We examined the extensive published healthcare utilization data in an effort to summarize what has been learned. Using multiple search techniques, data as of June 2003 from four different national Gulf War health registries and numerous hospitalization and ambulatory care reports were reviewed. Thus far, published reports have not revealed a unique Gulf War syndrome nor identified specific exposures that might explain postwar morbidity. Instead, they have demonstrated that Gulf War veterans have had an increase in multi-symptom condition, injury, and mental health diagnoses. While these diagnoses are similar to those experienced by other comparable military populations, their explanation is not fully understood. New strategies to identify risk factors for, and to reduce, such postdeployment conditions are summarized.

  15. Pertussis Accompanying Recent Mycoplasma Infection in a 10-Year-Old Girl

    PubMed Central

    Cheon, Mi Kyung; Na, Hyunju; Han, Seung Beom; Kwon, Hyo Jin; Chun, Yoon Hong

    2015-01-01

    Recently, the incidence of pertussis has been increasing; however, reports on mixed infection of pertussis with other respiratory pathogens are rare in highly immunized populations. We report the case of a 10-year-old girl who presented with cough, post-tussive emesis, and fever. She was subsequently diagnosed with bronchopneumonia. Although she had received five doses of diphtheria-tetanus-acellular pertussis vaccine, polymerase chain reaction of her nasopharyngeal aspirate confirmed Bordetella pertussis infection. In addition, serologic testing for Mycoplasma pneumoniae was also positive. The patient was treated with roxithromycin without any complications. This is the first report of mixed B. pertussis and M. pneumoniae infection in Korea. To avoid under-diagnosis, pertussis should be considered in patients with chronic cough even when other respiratory pathogens have been documented. PMID:26483996

  16. [Mosaic trisomy of chromosome 20 in a patient with congenital anomalies--10-years observation].

    PubMed

    Barg, Ewa; Gil, Justyna; Wikiera, Beata; Smigiel, Robert

    2009-01-01

    Trisomy 20 is one of the most often identified disorders in amniocytes, but in a postnatal analysis is detected rather rarely. We present a girl with dysmorphic features, congenital defects, tumor of a suprarenal gland, hypothyroidism and abnormal intelligence. The recognition of mosaic trisomy 20 was confirmed after cytogenetic examination of the skin fibroblast. The karyotype is described as mos 47,XX,+20/46,XX. The karyotype from peripheral blood lymphocytes, which was examined in the 1st year of life, was normal female (46,XX) and the Turner syndrome was excluded. During 10 years we observed that the dysmorphic features were increased and suggested genetic reasons of these features. In children with dysmorphic features and normal karyotype of blood lymphocytes a wide-ranged genetic counseling is necessary.

  17. Mutual influences between child emotion regulation and parent-child reciprocity support development across the first 10 years of life: Implications for developmental psychopathology.

    PubMed

    Feldman, Ruth

    2015-11-01

    Elucidating the mechanisms by which infant birth conditions shape development across lengthy periods is critical for understanding typical and pathological development and for targeted early interventions. This study examined how newborns' regulatory capacities impact 10-year outcomes via the bidirectional influences of child emotion regulation (ER) and reciprocal parenting across early development. Guided by dynamic systems theory, 125 infants were tested at seven time points: birth, 3, 6, 12, and 24 months and 5 and 10 years. Initial regulatory conditions were measured by respiratory sinus arrhythmia (RSA; vagal tone) and neurobehavioral regulation (Brazelton, 1973) at birth. At each assessment between 3 months and 5 years, infant ER was microcoded from age-appropriate paradigms and mother-child reciprocity observed during social interactions. Four regulation-related outcomes were measured at 10 years: child RSA, empathy measured by mother-child conflict discussion and a lab paradigm, accident proneness, and behavior problems. An autoregressive cross-lagged structural model indicated that infant birth conditions impacted 10-year outcomes via three mechanisms. First, child ER and reciprocal parenting were individually stable across development and were each predicted by regulatory birth conditions, describing gradual maturation of ER and reciprocity over time. Second, better ER skills at one time point were related to greater reciprocity at the next time point and vice versa, and these cross-time effects defined a field of individual-context mutual influences that mediated the links between neonatal RSA and 10-year outcomes. Third, direct associations emerged between neonatal regulation and outcome, suggesting that birth conditions may establish a neurobiological milieu that promotes a more mature and resilient system. These mechanisms describe distinct "attractor" states that constrain the system's future options, emphasize the importance of defining behavior

  18. Mutual influences between child emotion regulation and parent-child reciprocity support development across the first 10 years of life: Implications for developmental psychopathology.

    PubMed

    Feldman, Ruth

    2015-11-01

    Elucidating the mechanisms by which infant birth conditions shape development across lengthy periods is critical for understanding typical and pathological development and for targeted early interventions. This study examined how newborns' regulatory capacities impact 10-year outcomes via the bidirectional influences of child emotion regulation (ER) and reciprocal parenting across early development. Guided by dynamic systems theory, 125 infants were tested at seven time points: birth, 3, 6, 12, and 24 months and 5 and 10 years. Initial regulatory conditions were measured by respiratory sinus arrhythmia (RSA; vagal tone) and neurobehavioral regulation (Brazelton, 1973) at birth. At each assessment between 3 months and 5 years, infant ER was microcoded from age-appropriate paradigms and mother-child reciprocity observed during social interactions. Four regulation-related outcomes were measured at 10 years: child RSA, empathy measured by mother-child conflict discussion and a lab paradigm, accident proneness, and behavior problems. An autoregressive cross-lagged structural model indicated that infant birth conditions impacted 10-year outcomes via three mechanisms. First, child ER and reciprocal parenting were individually stable across development and were each predicted by regulatory birth conditions, describing gradual maturation of ER and reciprocity over time. Second, better ER skills at one time point were related to greater reciprocity at the next time point and vice versa, and these cross-time effects defined a field of individual-context mutual influences that mediated the links between neonatal RSA and 10-year outcomes. Third, direct associations emerged between neonatal regulation and outcome, suggesting that birth conditions may establish a neurobiological milieu that promotes a more mature and resilient system. These mechanisms describe distinct "attractor" states that constrain the system's future options, emphasize the importance of defining behavior

  19. Impact of the Active Healthy Kids Canada report card: a 10-year analysis.

    PubMed

    Tremblay, Mark S; Barnes, Joel D; Cowie Bonne, Jennifer

    2014-05-01

    For 20 years Active Healthy Kids Canada (AHKC) has worked to inspire the country to engage all children and youth in physical activity (PA). The primary vehicle to achieve this is the AHKC Report Card on Physical Activity for Children and Youth, which has been released annually since 2005. Using 10 years of experience with this knowledge translation and synthesis mechanism, this paper aggregates and consolidates diverse evidence demonstrating the impact of the Report Card and related knowledge translation activities. Over the years many evaluations, consultations, assessments, and surveys have helped inform changes in the Report Card to improve its impact. Guided by a logic model, the various assessments have traversed areas related to distribution and reach, meeting stakeholder needs, use of the Report Card, its influence on policy, and advancing the mission of AHKC. In the past 10 years, the Report Card has achieved > 1 billion media impressions, distributed > 120,000 printed copies and > 200,000 electronic copies, and benefited from a collective ad value > $10 million. The Report Card has been replicated in 14 countries, 2 provinces, 1 state and 1 city. AHKC has received consistent positive feedback from stakeholders and end-users, who reported that the Report Card has been used for public awareness/education campaigns and advocacy strategies, to strengthen partnerships, to inform research and program design, and to advance and adjust policies and strategies. Collectively, the evidence suggests that the Report Card has been successful at powering the movement to get kids moving, and in achieving demonstrable success on immediate and intermediate outcomes, although the long-term goal of improving the PA of Canadian children and youth remains to be realized. PMID:25426911

  20. Lamont-Doherty's Secondary School Field Research Program: 10 years of field research-based education.

    NASA Astrophysics Data System (ADS)

    Newton, R.; Vincent, S.; Gribbin, S.; Peteet, D. M.; Sambrotto, R.; Bostick, B. C.; Corbett, E.; Nguyen, K.; Bjornton, J.; Lee, D.; Dubossi, D.; Reyes, N.

    2014-12-01

    This fall marks the 10th year in which we have run a research-project-based educational program for high school students and science teachers at the Lamont-Doherty Earth Observatory. This summer's cohort included 31 teenagers, 7 science teachers, and 16 college students, most of whom are returning to the program to help run the research projects. Nearly all of our students attend non-competitive-entry public schools in NYC or the neighborhoods around the Observatory. Over 80% are from under-served minority populations. Most receive Title I/III assistance. About 60% are young women. During the past 10 years, nearly all of our participants have gone on to 4-year colleges. About half are declaring science and engineering majors. Our students receive scholarship support at rates several times higher than their graduating peers, including 5 Gates Millennium scholars over the past 5 years. Our science is centered on studies of a nearby tidal wetland, where we have expanded from fish collections in year one to include everything from sediment core analysis to soil chemistry to nutrient cycles to the local food web. In this presentation we will look back over 10 years of experience and focus on what lessons can be learned about (1) how to engage teams of young investigators in authentic scientific research; (2) what cultural/organizational structures encourage them to make use of place- and project-based learning and (3) what the participants themselves report as the most useful aspects of our programming. The presentation will include video clips from the students' field experiences and from reflective interviews with "graduates".

  1. Community Structure and Quality After 10 Years in Two Central Ohio Mitigation Bank Wetlands

    NASA Astrophysics Data System (ADS)

    Spieles, Douglas J.; Coneybeer, Meagan; Horn, Jonathan

    2006-11-01

    We evaluate two 10-year-old mitigation bank wetlands in central Ohio, one created and one with restored and enhanced components, by analysis of vegetation characteristics and by comparison of the year-10 vegetation and macroinvertebrate communities with reference wetlands. To assess different measures of wetland development, we compare the prevalence of native hydrophytes with an index of floristic quality and we evaluate the predictability of these parameters in year 10, given 5 years of data. Results show that the mitigation wetlands in this study meet vegetation performance criteria of native hydrophyte establishment by year 5 and maintain these characteristics through year 10. Species richness and floristic quality, as well as vegetative similarity with reference wetlands, differ among mitigation wetlands in year 1 and also in their rate of change during the first 10 years. The prevalence of native hydrophytes is reasonably predictable by year 10, but 5 years of monitoring is not sufficient to predict future trends of floristic quality in either the created or restored wetland. By year 10, macroinvertebrate taxa richness does not statistically differ among these wetlands, but mitigation wetlands differ from reference sites by tolerance index and by trophic guild dominance. The created wetland herbivore biomass is significantly smaller than its reference, whereas detritivore biomass is significantly greater in the created wetland and smaller in the restored wetland as compared with respective reference wetlands. These analyses illustrate differences in measures of wetland performance and contrast the monitoring duration necessary for legal compliance with the duration required for development of more complex indicators of ecosystem integrity.

  2. Impact of the Active Healthy Kids Canada report card: a 10-year analysis.

    PubMed

    Tremblay, Mark S; Barnes, Joel D; Cowie Bonne, Jennifer

    2014-05-01

    For 20 years Active Healthy Kids Canada (AHKC) has worked to inspire the country to engage all children and youth in physical activity (PA). The primary vehicle to achieve this is the AHKC Report Card on Physical Activity for Children and Youth, which has been released annually since 2005. Using 10 years of experience with this knowledge translation and synthesis mechanism, this paper aggregates and consolidates diverse evidence demonstrating the impact of the Report Card and related knowledge translation activities. Over the years many evaluations, consultations, assessments, and surveys have helped inform changes in the Report Card to improve its impact. Guided by a logic model, the various assessments have traversed areas related to distribution and reach, meeting stakeholder needs, use of the Report Card, its influence on policy, and advancing the mission of AHKC. In the past 10 years, the Report Card has achieved > 1 billion media impressions, distributed > 120,000 printed copies and > 200,000 electronic copies, and benefited from a collective ad value > $10 million. The Report Card has been replicated in 14 countries, 2 provinces, 1 state and 1 city. AHKC has received consistent positive feedback from stakeholders and end-users, who reported that the Report Card has been used for public awareness/education campaigns and advocacy strategies, to strengthen partnerships, to inform research and program design, and to advance and adjust policies and strategies. Collectively, the evidence suggests that the Report Card has been successful at powering the movement to get kids moving, and in achieving demonstrable success on immediate and intermediate outcomes, although the long-term goal of improving the PA of Canadian children and youth remains to be realized.

  3. Neurocognition and Duration of Psychosis: A 10-year Follow-up of First-Episode Patients.

    PubMed

    Rund, Bjørn Rishovd; Barder, Helene Eidsmo; Evensen, Julie; Haahr, Ulrik; ten Velden Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Johannes; Larsen, Tor Ketil; Melle, Ingrid; Opjordsmoen, Stein; Røssberg, Jan Ivar; Simonsen, Erik; Sundet, Kjetil; Vaglum, Per; McGlashan, Thomas; Friis, Svein

    2016-01-01

    A substantial proportion of schizophrenia-spectrum patients exhibit a cognitive impairment at illness onset. However, the long-term course of neurocognition and a possible neurotoxic effect of time spent in active psychosis, is a topic of controversy. Furthermore, it is of importance to find out what predicts the long-term course of neurocognition. Duration of untreated psychosis (DUP), accumulated time in psychosis the first year after start of treatment, relapse rates and symptoms are potential predictors of the long-term course. In this study, 261 first-episode psychosis patients were assessed neuropsychologically on one or more occasions. Patients were tested after remission of psychotic symptoms and reassessed 1, 2, 5, and 10 years after inclusion. The neurocognitive battery consisted of California Verbal Learning Test, Wisconsin Card Sorting Test, Controlled Oral Word Association Task, Trail Making A and B, and Finger Tapping. We calculated a composite score by adding the z-scores of 4 tests that were only moderately inter-correlated, not including Finger Tapping. Data were analyzed by a linear mixed model. The composite score was stable over 10 years. No significant relationship between psychosis before (DUP) or after start of treatment and the composite score was found, providing no support for the neurotoxicity hypothesis, and indicating that psychosis before start of treatment has no significant impact on the course and outcome in psychosis. We found no association between symptoms and the neurocognitive trajectory. Stable remission during the first year predicted neurocognitive functioning, suggesting that the early clinical course is a good predictor for the long-term course.

  4. Nonconventional Methods in Teaching Matter, Atoms, Molecules and the Periodic Table for Nonmajor Students.

    ERIC Educational Resources Information Center

    Cherif, Abour A.; Adams, Gerald E.; Cannon, Charles E.

    1997-01-01

    Describes several activities used to teach students from middle school age to college nonmajors about the nature of matter, atoms, molecules and the periodic table. Strategies integrate such approaches as hands-on activities, visualization, writing, demonstrations, role play, and guided inquiry. For example, the periodic table is viewed as a town…

  5. 26 CFR 601.204 - Changes in accounting periods and in methods of accounting.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... accounting. 601.204 Section 601.204 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601... changes his accounting period shall, before using the new period for income tax purposes, comply with...

  6. 26 CFR 601.204 - Changes in accounting periods and in methods of accounting.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... accounting. 601.204 Section 601.204 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601... changes his accounting period shall, before using the new period for income tax purposes, comply with...

  7. A Method of Speech Periodicity Enhancement Using Transform-domain Signal Decomposition☆

    PubMed Central

    Lee, Tan; Kleijn, W. Bastiaan; Kong, Ying-Yee

    2015-01-01

    Periodicity is an important property of speech signals. It is the basis of the signal’s fundamental frequency and the pitch of voice, which is crucial to speech communication. This paper presents a novel framework of periodicity enhancement for noisy speech. The enhancement is applied to the linear prediction residual of speech. The residual signal goes through a constant-pitch time warping process and two sequential lapped-frequency transforms, by which the periodic component is concentrated in certain transform coefficients. By emphasizing the respective transform coefficients, periodicity enhancement of noisy residual signal is achieved. The enhanced residual signal and estimated linear prediction filter parameters are used to synthesize the output speech. An adaptive algorithm is proposed for adjusting the weights for the periodic and aperiodic components. Effectiveness of the proposed approach is demonstrated via experimental evaluation. It is observed that harmonic structure of the original speech could be properly restored to improve the perceptual quality of enhanced speech. PMID:26150679

  8. Estimation of soil water storage using temporal stability in four land uses over 10 years on the Loess Plateau, China

    NASA Astrophysics Data System (ADS)

    Liu, Bingxia; Shao, Ming'an

    2014-09-01

    An understanding of the temporal stability of soil water storage (SWS) in deep soil profiles is critical to optimize monitoring strategies and to predict the status of soil water on the Loess Plateau. This study tested and validated the feasibility of estimating mean SWS over multiple years by the SWSs at selected locations. The SWSs in 0-1, 1-2, 2-3, and 3-4 m layers were collected using neutron probes at 11 sites in each of four land-use types: cropland (CL), grassland (GL), fallow land (FL), and shrubland (SL). The most time-stable locations (MTSLs) for the various layers and the location at mid-slope for each land use were selected on 20 sampling occasions during a calibration period from July 2004 to December 2005. A validation data sets from January 2006 to October 2013 was used to test the length of time the estimates of mean SWS remained valid. The SWSs in SL and GL decreased with plant growth, and the temporal variations were larger in SL and GL than in FL and CL. The temporal stability of the SWSs was high for all soil layers in four land uses, with the rank correlations over the threshold of significance (α = 0.05) over 10 years. The degree of temporal stability of SWSs was ranked as CL > FL > GL > SL, and the temporal stability of SWSs in SL and GL decreased with increasing lengths of observation period, as indicated by lower mean Spearman's correlations for all soil layers. The MTSLs selected from the calibration period could accurately estimate mean SWSs for diverse layers under four land uses with estimation errors less than 10% over eight years. The study verified that a single location at mid-slope of each land use could be sampled in order to reduce the required number of samples and save time and labor while maintaining a high accuracy of prediction over multiple years.

  9. Rosetta begins its 10-year journey to the origins of the Solar System

    NASA Astrophysics Data System (ADS)

    2004-03-01

    Rosetta’s mission began at 08h17 CET (07h17 GMT) on 2 March when a European Ariane 5 launch vehicle liftered off from the Guiana Space Centre, Europe’s spaceport in Kourou, French Guiana. The launcher successfully placed its upper stage and payload into an eccentric coast orbit (200 x 4000 km). About two hours later, at 10h14 CET (09h14 GMT) the upper stage ignited its own engine to reach an escape velocity in order to leave the Earth’s gravity field and enter heliocentric orbit. The Rosetta probe was released about 18 minutes later. “After the recent success of Mars Express, Europe is now heading to deep space with another fantastic mission. We will have to be patient, as the rendezvous with the comet will not take place until ten years from now, but I think it’s worth the wait” said ESA’s Director General Jean-Jacques Dordain witnessing the launch from Kourou. ESA’s Operations Centre (ESOC) in Darmstadt, Germany, has established contact with the probe as it flies away from Earth at a relative speed of about 3.4 km/s. ESOC will be in charge of Rosetta operations and orbit determination throughout the mission. During the next eight months, the spacecraft’s onboard systems will be checked and its science payload will be commissioned. A 10-year odyssey Rosetta will be reactivated for planetary flybys, which will be used to modify its trajectory through gravity assist manoeuvres. During the trip, the probe could also observe one or more asteroids, observation of asteroids being one of the mission's secondary objectives. The first planetary encounter will be in March 2005, as Rosetta flies by the Earth for the first time. The gravity assist will boost Rosetta into an orbit that will take it to Mars two years later. During its close encounter with Mars in February 2007, Rosetta will approach to a distance of about 200 km and conduct science observations. This Martian flyby will be followed by another Earth flyby in November the same year. Both

  10. Midline Crossing: Developmental Trend from 3 to 10 Years of Age in a Preferential Card-Reaching Task

    ERIC Educational Resources Information Center

    Carlier, M.; Doyen, A.-L.; Lamard, C.

    2006-01-01

    We assessed 110 left-handed and 322 right-handed children aged from 3 to 10 years, using Bishop's card-reaching task. Manual body midline crossings were observed. A regular developmental trend was observed from 3 to 10 years: older children crossed the body midline more frequently when reaching for cards than did younger children. The factor age…

  11. Subclinical Hypothyroidism Is Associated with Increased Risk for Cancer Mortality in Adult Taiwanese—A 10 Years Population-Based Cohort

    PubMed Central

    Tseng, Fen-Yu; Lin, Wen-Yuan; Li, Chia-Ing; Li, Tsai-Chung; Lin, Cheng-Chieh; Huang, Kuo-Chin

    2015-01-01

    Background The association between subclinical hypothyroidism (SCH) and cancer mortality is seldom discussed. Methods A total of 115,746 participants without thyroid disease history, aged 20 and above, were recruited from four nationwide health screening centers in Taiwan from 1998 to 1999. SCH was defined as a serum thyroid-stimulating hormone (TSH) level of 5.0–19.96 mIU/L with normal total thyroxine concentrations. Euthyroidism was defined as a serum TSH level of 0.47–4.9 mIU/L. Cox proportional hazards regression analyses were used to estimate the relative risks (RRs) of death from cancer for adults with SCH during a 10-year follow-up period. Results Among 115,746 adults, 1,841 had SCH (1.6%) and 113,905 (98.4%) had euthyroidism. There were 1,532 cancer deaths during the 1,034,082 person-years follow-up period. Adjusted for age, gender, body mass index, diabetes, hypertension, dyslipidemia, smoking, alcohol drinking, betel nut chewing, physical activity, income, and education level, the RRs (95% confidence interval) of cancer deaths among subjects with SCH versus euthyroid subjects were 1.51 (1.06 to 2.15). Cancer site analysis revealed a significant increased risk of bone, skin and breast cancer among SCH subjects (RR 2.79, (1.01, 7.70)). The risks of total cancer deaths were more prominent in the aged (RR 1.71, (1.02 to 2.87)), in females (RR 1.69 (1.08 to 2.65)), and in heavy smokers (RR 2.24, (1.19 to 4.21)). Conclusions Subjects with SCH had a significantly increased risk for cancer mortality among adult Taiwanese. This is the first report to demonstrate the association between SCH and cancer mortality. PMID:25830770

  12. Measuring the band structures of periodic beams using the wave superposition method

    NASA Astrophysics Data System (ADS)

    Junyi, L.; Ruffini, V.; Balint, D.

    2016-11-01

    Phononic crystals and elastic metamaterials are artificially engineered periodic structures that have several interesting properties, such as negative effective stiffness in certain frequency ranges. An interesting property of phononic crystals and elastic metamaterials is the presence of band gaps, which are bands of frequencies where elastic waves cannot propagate. The presence of band gaps gives this class of materials the potential to be used as vibration isolators. In many studies, the band structures were used to evaluate the band gaps. The presence of band gaps in a finite structure is commonly validated by measuring the frequency response as there are no direct methods of measuring the band structures. In this study, an experiment was conducted to determine the band structure of one dimension phononic crystals with two wave modes, such as a bi-material beam, using the frequency response at only 6 points to validate the wave superposition method (WSM) introduced in a previous study. A bi-material beam and an aluminium beam with varying geometry were studied. The experiment was performed by hanging the beams freely, exciting one end of the beams, and measuring the acceleration at consecutive unit cells. The measured transfer function of the beams agrees with the analytical solutions but minor discrepancies. The band structure was then determined using WSM and the band structure of one set of the waves was found to agree well with the analytical solutions. The measurements taken for the other set of waves, which are the evanescent waves in the bi-material beams, were inaccurate and noisy. The transfer functions at additional points of one of the beams were calculated from the measured band structure using WSM. The calculated transfer function agrees with the measured results except at the frequencies where the band structure was inaccurate. Lastly, a study of the potential sources of errors was also conducted using finite element modelling and the errors in

  13. Analysis of complications from 600 retroperitoneoscopic procedures of the upper urinary tract during the last 10 years

    PubMed Central

    Liapis, Dimitri; De La Taille, Alexandre; Ploussard, Guillaume; Robert, Grégoire; Bastien, Laurence; Hoznek, Andras; Vordos, Dimitri; Abbou, Claude; Salomon, Laurent

    2008-01-01

    Introduction The aim of this study is to review 10 years experience of retroperitoneoscopy procedures. Methods 600 patients treated between 1995 and 2007 netroperitoneoscopy (nephrectomy, partial and total nephrectomy, adrenalectomy, pyeloplasty, renal cyst, calyceal diverticulectomy) were reviewed for per, peri and post operative complications including patients in the learning curve. Results The mean blood loss was 159mL. Conversion to open surgery was required in 28 patients (4.6%) primarily due to technical problems during dissection (elective). There were 32 (5.3%) surgical complications, including bleeding or hematomas in 12 cases and 2 of them required reintervention, urinomas in 8 which were treated by installation of a ureteral drainage (JJ stent). Wound or deep abscesses happened in 4, urinary fistula in 1 and pancreatic fistula in another. Evisceration (hernias) was seen in 3 patients. Intestinal injury occurred in 2. The complication rate depended on the difficulty of the procedure and learning curve of the surgeon. Twenty eight patients (4.6%) presented medical post-operative complications (hyperthermias, deep venous thrombosis, pyelonephritis, pulmonary superinfections, pulmonary atelectasia and transient vascular ischemic accident). Mean postoperative hospital stay was 6.2 days (ranged from 2 to 20). Conclusion Retroperitoneoscopy can be the technique of choice for accessing and carrying out all the surgery of the upper urinary tract respecting the principles of oncological surgery. After experience with 600 cases during the last 10 years the technique has become safe, simplified, reproducible and effective although not easy. Most complications are minor and easily managed. PMID:18807049

  14. Evaluation of Haemophilus influenzae type b carrier status among children 10 years after the introduction of Hib vaccine in Brazil

    PubMed Central

    Zanella, Rosemeire Cobo; Brandileone, Maria Cristina de Cunto; Andrade, Ana Lúcia; Ogassavara, Cinthya Terumi; Fiório, Cleiton Eduardo; Brandão, Angela Pires; Almeida, Samanta Cristine Grassi; Lemos, Ana Paula Silva; Gorla, Maria Cecília; Carvalhanas, Telma Regina; Sato, Helena; Liphaus, Bernadete; Nerger, Maria Lígia; Conde, Monica; Ribeiro, Ana Freitas

    2015-01-01

    The aim of the present study was to assess the prevalence of Haemophilus influenzae type b (Hib) nasopharyngeal (NP) colonisation among healthy children where Hib vaccination using a 3p+0 dosing schedule has been routinely administered for 10 years with sustained coverage (> 90%). NP swabs were collected from 2,558 children who had received the Hib vaccine, of whom 1,379 were 12-< 24 months (m) old and 1,179 were 48-< 60 m old. Hi strains were identified by molecular methods. Hi carriage prevalence was 45.1% (1,153/2,558) and the prevalence in the 12-< 24 m and 48-< 60 m age groups were 37.5% (517/1,379) and 53.9% (636/1,179), respectively. Hib was identified in 0.6% (16/2,558) of all children in the study, being 0.8% (11/1,379) and 0.4% (5/1,179) among the 12-< 24 m and 48-< 60 m age groups, respectively. The nonencapsulate Hi colonisation was 43% (n = 1,099) and was significantly more frequent at 48-< 60 m of age (51.6%, n = 608) compared with that at 12-< 24 m of age (35.6%, n = 491). The overall resistance rates to ampicillin and chloramphenicol were 16.5% and 3.7%, respectively; the co-resistance was detected in 2.6%. Our findings showed that the Hib carrier rate in healthy children under five years was very low after 10 years of the introduction of the Hib vaccine. PMID:26517654

  15. 24 CFR 241.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-Supplemental Loans To Finance Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems.... No energy saving loan shall have an amortization period in excess of 15 years unless the amount...

  16. 24 CFR 241.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-Supplemental Loans To Finance Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems.... No energy saving loan shall have an amortization period in excess of 15 years unless the amount...

  17. 24 CFR 241.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-Supplemental Loans To Finance Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems.... No energy saving loan shall have an amortization period in excess of 15 years unless the amount...

  18. 24 CFR 241.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-Supplemental Loans To Finance Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems.... No energy saving loan shall have an amortization period in excess of 15 years unless the amount...

  19. 24 CFR 241.540 - Method of loan payment and amortization period.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-Supplemental Loans To Finance Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems.... No energy saving loan shall have an amortization period in excess of 15 years unless the amount...

  20. A Study on the Bacteriological Profile and Antibiogram of Bacteremia in Children Below 10 Years in a Tertiary Care Hospital in Bangalore, India

    PubMed Central

    Tiwari, Devendra Kumar; Golia, Saroj; K.T., Sangeetha; C.L., Vasudha

    2013-01-01

    Introduction: Blood stream infections are very common in the pediatric age group. Patients with bacteremia may have either a transient bacteremia that may be rapidly and permanently cleared by a patient’s host defenses with no major consequences, or persistent bacteremia which can be self-limited without development of focal infection or sequelae, or may progress to a more serious fatal infection or toxic symptoms. Objectives: The aim of our study is to analyze the hospital data on bacteremia in children less than 10 years with special reference to male and female cases, the pathogens involved, and the antibiotic susceptibility patterns. Methods: Over a one year period samples were collected from 128 children who included all newborn babies and children admitted with fever and suspected of having sepsis. Blood was collected depending upon age groups with aseptic precaution and incubated at 37oC for 10 days. Subcultures were made on blood agar and MacConkey agar plates. Organisms were identified and antibiotic sensitivity test of the isolates were performed. Results: Out of 128 suspected cases, 32 (25%) was culture positive. Male to female ratio is 1.28:1.0. Klebsiella species (43.75%) was the most common organism isolated followed by Staphylococcus aureus (18.75%). Prevalence of gram negative organism was 71.87%. Most of the gram negative organisms showed maximum resistance to ampicillin and the gram positive organisms to penicillin. In this study three gram negative organisms were extended-spectrum beta lactamases (ESBLs) producers and one Pseudomonas aeruginosa was metallo-beta lactamase (MBL) producer. 33.33% of staphylococcus aureus was Methicillin resistant Staphylococcus aureus (MRSA) strains. Interpretation and Conclusion: This study showed a 25% prevalence rate of bacteremia among children with an increasing prevalence in the age group of 5-10 years and also an observed decline in susceptibility of the pathogens to common antibiotics which ultimately