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Sample records for 11mo sd 1y

  1. Ab initio calculations of magnetic properties of the interstitially doped YFe11Mo compound

    NASA Astrophysics Data System (ADS)

    Kokorina, E. E.; Medvedev, M. V.; Nekrasov, I. A.

    2016-02-01

    The recent increase in the number of studies of RFe11- x M x compounds is related to their promising application as permanent magnets. However, the insufficiently high value of the Curie temperature T C of these compounds is a barrier to their widespread use. The increase in the Curie temperature of these compounds is achieved by doping with the light nonmetallic atoms such as hydrogen, nitrogen, and carbon. In this paper, it is shown numerically that this doping leads to drastic changes of the electronic band dispersions in a wide energy region around the Fermi level. This in turn changes values of the magnetic moments of ions and Heisenberg exchange interaction parameters. The values of ab initio calculated magnetic moments and direct exchange interaction parameters make it possible to calculate the Curie temperatures for both parent and nitrogen-doped compounds within the mean-field approach to the Heisenberg model in the sample of YFe11Mo, a typical representative of the R(Fe,M)12L class. Theoretical values of T C obtained for YFe11Mo and YFe11MoN (514 and 723 K respectively) are consistent with experimental ones (472 and 664 K) with an accuracy of 10%. Also, the calculated increase in T C upon nitrogenization (about 200 K) is in good agreement with the experimental data.

  2. Combined iron and folic acid supplementation with or without zinc reduces time to walking unassisted among Zanzibari infants 5- to 11-mo old.

    PubMed

    Olney, Deanna K; Pollitt, Ernesto; Kariger, Patricia K; Khalfan, Sabra S; Ali, Nadra S; Tielsch, James M; Sazawal, Sunil; Black, Robert; Allen, Lindsay H; Stoltzfus, Rebecca J

    2006-09-01

    Iron and zinc deficiencies have been associated with delayed motor development in nutritionally at-risk children, albeit inconsistently. In this community-based, randomized double-blind trial, iron+folic acid (FeFA) (12.5 mg Fe + 50 mug folic acid), zinc (Zn) (10 mg), and iron+folic acid+zinc (FeFA+Zn) supplements or a placebo were given daily for 1 y to nutritionally at-risk children in Pemba, Zanzibar. The effects of these treatments on attaining unassisted walking were evaluated using survival analysis for 354 children aged 5-11 mo at the start of supplementation. Treatment effects on changes in hemoglobin (Hb) and zinc protoporphyrin (ZPP) and height-for-age (HAZ) and weight-for-age (WAZ) Z scores were evaluated using linear regression. Attained motor milestone was recorded every 2 wk for 1 y. Hb, ZPP, HAZ, and WAZ were measured at baseline and after 6 mo of treatment. FeFA with or without Zn reduced the time it took for children to walk assisted. Children who received any iron walked unassisted sooner than those who received no iron [median difference approximately 15 d, P = 0.035, risk ratio (RR) = 1.28, 95% CI = 1.02, 1.61] and this effect was stronger in those who had iron deficiency anemia (IDA) at baseline (median difference was approximately 30 d; P = 0.002; RR = 1.68; 95% CI = 1.21, 2.32). FeFA alone and Zn alone improved Hb and ZPP compared with placebo. There were no significant treatment effects on changes in HAZ or WAZ. The effects of treatment on time to walking may have been mediated by improvements in iron status or hemoglobin, but were not mediated through improvements in growth. PMID:16920865

  3. SD46 Facilities and Capabilities

    NASA Technical Reports Server (NTRS)

    Ramachandran, N.; Curreri, Peter A. (Technical Monitor)

    2002-01-01

    The displays for the Materials Conference presents some of the facilities and capabilities in SD46 that can be useful to a prospective researcher from University, Academia or other government labs. Several of these already have associated personnel as principal and co-investigators on NASA peer reviewed science investigations. 1. SCN purification facility 2. ESL facility 3. Static and Dynamic magnetic field facility 4. Microanalysis facility 5. MSG Investigation - PFMI 6. Thermo physical Properties Measurement Capabilities.

  4. The SD oscillator and its attractors

    NASA Astrophysics Data System (ADS)

    Cao, Q.; Wiercigroch, M.; Pavlovskaia, E.; Grebogi, C.; Michael, J.; Thompson, T.

    2008-02-01

    We propose a new archetypal oscillator for smooth and discontinuous systems (SD oscillator). This oscillator behaves both smooth and discontinuous system depending on the value of the smoothness parameter. New dynamic behaviour is presented for the transitions from the smooth to discontinuous regime.

  5. NDPC-SD Data Probes Worksheet

    ERIC Educational Resources Information Center

    National Dropout Prevention Center for Students with Disabilities, 2011

    2011-01-01

    This worksheet from the National Dropout Prevention Center for Students with Disabilities (NDPC-SD) is an optional tool to help schools organize multiple years of student and program data for the purpose of identifying school-completion needs that can be addressed through the implementation of research-based interventions. It is designed for use…

  6. Experimental study of upper sd shell nuclei and evolution of sd-fp shell gap

    SciTech Connect

    Sarkar, M. Saha

    2012-06-27

    The intruder orbitals from the fp shell play important role in the structure of nuclei around the line of stability in the upper sd shell. Experimentally we have studied {sup 35}Cl, {sup 30}P, {sup 36}Cl, {sup 37}Ar and {sup 34}Cl in this mass region using the INGA setup. Large basis cross-shell shell model calculations have indicated the need for change of the sd-fp energy gap for reliable reproduction of negative parity and high spin positive parity states. Indication of population of states of large deformation has been found in our data. Theoretical interpretation of these states has been discussed.

  7. Understanding nuclei in the upper sd - shell

    SciTech Connect

    Sarkar, M. Saha; Bisoi, Abhijit; Ray, Sudatta; Kshetri, Ritesh; Sarkar, S.

    2014-08-14

    Nuclei in the upper-sd shell usually exhibit characteristics of spherical single particle excitations. In the recent years, employment of sophisticated techniques of gamma spectroscopy has led to observation of high spin states of several nuclei near A ≃ 40. In a few of them multiparticle, multihole rotational states coexist with states of single particle nature. We have studied a few nuclei in this mass region experimentally, using various campaigns of the Indian National Gamma Array setup. We have compared and combined our empirical observations with the large-scale shell model results to interpret the structure of these nuclei. Indication of population of states of large deformation has been found in our data. This gives us an opportunity to investigate the interplay of single particle and collective degrees of freedom in this mass region.

  8. Final report of the safety assessment of Alcohol Denat., including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the denaturants, Quassin, Brucine Sulfate/Brucine, and Denatonium Benzoate.

    PubMed

    2008-01-01

    Alcohol Denat. is the generic term used by the cosmetics industry to describe denatured alcohol. Alcohol Denat. and various specially denatured (SD) alcohols are used as cosmetic ingredients in a wide variety of products. Many denaturants have been previously considered, on an individual basis, as cosmetic ingredients by the Cosmetic Ingredient Review (CIR) Expert Panel, whereas others, including Brucine and Brucine Sulfate, Denatonium Benzoate, and Quassin, have not previously been evaluated. Quassin is a bitter alkaloid obtained from the wood of Quassia amara. Quassin has been used as an insect antifeedant and insecticide and several studies demonstrate its effectiveness. At oral doses up to 1000 mg/kg using rats, Quassin was not toxic in acute and short-term tests, but some reversible piloerection, decrease in motor activity, and a partial loss of righting reflex were found in mice at 500 mg/kg. At 1000 mg/kg given intraperitoneally (i.p.), all mice died within 24 h of receiving treatment. In a cytotoxicity test with brine shrimp, 1 mg/ml of Quassin did not possess any cytotoxic or antiplasmodial activity. Quassin administered to rat Leydig cells in vitro at concentrations of 5-25 ng/ml inhibited both the basal and luteinizing hormone (LH)-stimulated testosterone secretion in a dose-related fashion. Quassin at doses up to 2.0 g/kg in drinking water using rats produced no significant effect on the body weights, but the mean weights of the testes, seminal vesicles, and epididymides were significantly reduced, and the weights of the anterior pituitary glands were significantly increased. The sperm counts and levels of LH, follicle-stimulating hormone (FSH), and testosterone were significantly lower in groups treated with Quassin. Brucine is a derivative of 2-hydroxystrychnine. Swiss-Webster mice given Brucine base, 30 ml/kg, had an acute oral LD(50) of 150 mg/kg, with central nervous system depression followed by convulsions and seizures in some cases. In those

  9. User's Manual for Space Debris Surfaces (SD_SURF)

    NASA Technical Reports Server (NTRS)

    Elfer, N. C.

    1996-01-01

    A unique collection of computer codes, Space Debris Surfaces (SD_SURF), have been developed to assist in the design and analysis of space debris protection systems. SD_SURF calculates and summarizes a vehicle's vulnerability to space debris as a function of impact velocity and obliquity. An SD_SURF analysis will show which velocities and obliquities are the most probable to cause a penetration. This determination can help the analyst select a shield design which is best suited to the predominant penetration mechanism. The analysis also indicates the most suitable parameters for development or verification testing. The SD_SURF programs offer the option of either FORTRAN programs and Microsoft EXCEL spreadsheets and macros. The FORTRAN programs work with BUMPERII version 1.2a or 1.3 (Cosmic released). The EXCEL spreadsheets and macros can be used independently or with selected output from the SD_SURF FORTRAN programs.

  10. Substellar objects around the sdB eclipsing Binaries

    NASA Astrophysics Data System (ADS)

    Zhu, Liying; Qian, Shengbang; Liao, Wenping; Zhao, Ergang; Li, Linjia

    2016-07-01

    The sdB-type eclipsing binary consists a very hot subdwarf B (sdB) type primary and a low mass secondary with short period. They are detached binaries and show very narrow eclipse profiles, which benefits the determination of the precise eclipse times. With the precise times of light minimum, we can detected small mass objects around them by analyzing the observed-calculated (O-C) curve based on the light time effect. For searching the substellar objects orbiting around the binaries, we have monitored sdB-type eclipsing binaries for decades. A group of brown dwarfs and planets have been detected since then. In the present paper, we focus on the target NSVS07826147, which may be another exoplanet host candidate among the group of the sdB-type eclipsing binaries.

  11. Photometric Survey to Search for Field sdO Pulsators

    NASA Astrophysics Data System (ADS)

    Johnson, C.; Green, E.; Wallace, S.; O'Malley, C.; Amaya, H.; Biddle, L.; Fontaine, G.

    2014-04-01

    We present the results of a campaign to search for subdwarf O (sdO) star pulsators among bright field stars. The motivation for this project is the recent discovery by Randall et al. (2011) of four rapidly pulsating sdO stars in the globular cluster ω Cen, with Teff near 50,000 K, 5.4 < log g < 6.0, and hydrogen-rich atmospheres. The only previously known sdO pulsator is significantly hotter at 68,500 K and log g = 6.1. All of the sdO pulsators identified so far are fainter than V≍17.4 and, thus, are poor candidates for an in-depth follow-up with asteroseismology. We therefore obtained high S/N light curves and spectroscopy for a number of field sdO stars to attempt to discover bright counterparts to these stars, particularly the ω Cen pulsators. Our primary sample consisted of 19 sdO stars with hydrogen-rich atmospheres, log N(He)/N(H) < -1.0, effective temperatures in the range 40,000 K < Teff < 67,000 K, and surface gravities 5.3 < log g < 6.1. We also observed 17 additional helium-rich sdO stars with log N(He)/N(H) > -0.1 and similar temperatures and gravities. To date, we have found no detectable pulsations at amplitudes above 0.08% (4 times the mean noise level) in any of the 36 field sdO stars that we observed. The presence of pulsations in ω Cen sdO stars and their apparent absence in seemingly comparable field sdO stars is perplexing. While very suggestive, the significance of this result is difficult to assess more completely right now due to remaining uncertainties about the temperature width and purity of the ω Cen instability strip and the existence of any sdO pulsators with weaker amplitudes than the current detection limit in globular clusters.

  12. Composite particle representation for light sd shell nuclei

    SciTech Connect

    Collinson, D.F.

    1986-01-01

    The Composite Particle Representation is applied to light sd shell nuclei /sup 20/O, /sup 20/F and /sup 20/Ne. The energy spectrum is found to agree exactly with the shell model in all cases. The CPR theory is then used to examine the possible boson structure of sd shell wavefunctions. Only in the case of /sup 20/O are the wavefunctions found to have a high boson probability.

  13. Purification, Characterization, and Optimum Conditions of Fermencin SD11, a Bacteriocin Produced by Human Orally Lactobacillus fermentum SD11.

    PubMed

    Wannun, Phirawat; Piwat, Supatcharin; Teanpaisan, Rawee

    2016-06-01

    Fermencin SD11, a bacteriocin produced by human orally Lactobacillus fermentum SD11, was purified, characterized, and optimized in conditions for bacterial growth and bacteriocin production. Fermencin SD11 was purified using three steps of ammonium sulfate precipitation, gel filtration chromatography, and reverse-phase high-performance liquid chromatography. The molecular weight was found to be 33,000 Da using SDS-PAGE and confirmed as 33,593.4 Da by liquid chromatography-mass spectrometry. Fermencin SD11 exhibited activity against a wide range of oral pathogens including cariogenic and periodontogenic pathogens and Candida. The active activity was stable between 60 - 80 °C in a pH range of 3.0 to 7.0. It was sensitive to proteolytic enzymes (proteinase K and trypsin), but it was not affected by α-amylase, catalase, lysozyme, and saliva. The optimum conditions for growth and bacteriocin production of L. fermentum SD11 were cultured at acidic with pH of 5.0-6.0 at 37 or 40 °C under aerobic or anaerobic conditions for 12 h. It is promising that L. fermentum SD11 and its bacteriocin may be an alternative approach for promoting oral health or prevention of oral diseases, e.g., dental caries and periodontitis, which would require further clinical trials. PMID:26892008

  14. Microwave Spectrum of the SD+3 Ion: Molecular Structure.

    PubMed

    Araki; Ozeki; Saito

    1998-11-01

    The J = 1-0 to 4-3 spectral lines of SD+3 were measured in the 152-610 GHz region using a source-modulated microwave spectrometer. The SD+3 ion was generated in a free space absorption cell by a hollow-cathode discharge in a gas mixture of D2S and D2. The rotational constant B0 and the centrifugal distortion constants DJ and DJK were determined from the measured frequencies. A vibration-rotation analysis was carried out and the rz structures of SH+3 and SD+3 were derived from their zero point averaged rotational constants, expressed as SH+3: rz = 1.36512(22) Å and thetaz = 94.098(26) degrees, and SD+3: rz = 1.36086(16) Å and thetaz = 94.1211(195) degrees, where the difference between thetaz(HSH) and thetaz(DSD) was assumed to be the same as that between thetaz(HPH) of PH3 and thetaz(DPD) of PD3. From the shift between the rz structures of SH+3 and SD+3, the re structure of SH+3 was estimated to be re = 1.35001(113) Å, thetae = 94.181(135) degrees. Copyright 1998 Academic Press. PMID:9770407

  15. Decay out of SD Band in ^192Pb

    NASA Astrophysics Data System (ADS)

    McNabb, D. P.; Cizewski, J. A.; Ding, K. Y.; Fotiades, N.; Archer, D. E.; Becker, J. A.; Bernstein, L. A.; Hauschild, K.; Younes, W.; Clark, R. M.; Fallon, P.; Lee, I. Y.; Macchiavelli, A. O.; MacLeod, R. W.

    1997-04-01

    Gamma-ray transitions linking the yrast SD bands to the known (ND) levels have been found in ^194Pb(M. J. Brinkman, et al., Phys. Rev. C53), R1461 (1996), A. Lopez-Martens, et al., Phys. Lett. B380, 18 (1996) and K. Hauschild, et al., submitted to Phys. Rev. C (1996). and ^194Hg.(T. L. Khoo, et al., Phys. Rev. Lett. 76), 1583 (1996). The spin, parity and excitation energy of these SD bands were established. Linking transitions are understood as arising from ND states nearby in excitation energy which are admixed with the SD states.(E. Vigezzi, et al., Phys. Lett. B249), 163 (1990). We anticipate a smaller phase space for quasicontinuous decay of the SD band in ^192Pb because it is predicted to lie lower in excitation than the SD band in ^194Pb.footnote S. J. Krieger, et al. Nucl. Phys. A542, 43 (1992). To search for linking transitions in ^192Pb we used the Gammasphere array at LBNL and the ^24Mg(^173Yb,5n) reaction at 134 MeV. Candidates for linking transitions and general features of the decay will be discussed.

  16. SD-CAS: Spin Dynamics by Computer Algebra System.

    PubMed

    Filip, Xenia; Filip, Claudiu

    2010-11-01

    A computer algebra tool for describing the Liouville-space quantum evolution of nuclear 1/2-spins is introduced and implemented within a computational framework named Spin Dynamics by Computer Algebra System (SD-CAS). A distinctive feature compared with numerical and previous computer algebra approaches to solving spin dynamics problems results from the fact that no matrix representation for spin operators is used in SD-CAS, which determines a full symbolic character to the performed computations. Spin correlations are stored in SD-CAS as four-entry nested lists of which size increases linearly with the number of spins into the system and are easily mapped into analytical expressions in terms of spin operator products. For the so defined SD-CAS spin correlations a set of specialized functions and procedures is introduced that are essential for implementing basic spin algebra operations, such as the spin operator products, commutators, and scalar products. They provide results in an abstract algebraic form: specific procedures to quantitatively evaluate such symbolic expressions with respect to the involved spin interaction parameters and experimental conditions are also discussed. Although the main focus in the present work is on laying the foundation for spin dynamics symbolic computation in NMR based on a non-matrix formalism, practical aspects are also considered throughout the theoretical development process. In particular, specific SD-CAS routines have been implemented using the YACAS computer algebra package (http://yacas.sourceforge.net), and their functionality was demonstrated on a few illustrative examples. PMID:20843716

  17. Reading Performance Correlates with White-Matter Properties in Preterm and Term Children

    ERIC Educational Resources Information Center

    Andrews, James S.; Ben-Shachar, Michal; Yeatman, Jason D.; Flom, Lynda L.; Luna, Beatriz; Feldman, Heidi M.

    2010-01-01

    Aim: We used diffusion tensor imaging to investigate the association between white-matter integrity and reading ability in a cohort of 28 children. Nineteen preterm children (14 males, five females; mean age 11y 11mo [SD 1y 10mo], mean gestational age 30.5wks (SD 3.2), mean birthweight was 1455g [SD 625]); and nine term children (five males, four…

  18. 78 FR 39820 - Standing Rock Sioux Tribe Disaster #SD-00058

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ... ADMINISTRATION Standing Rock Sioux Tribe Disaster SD-00058 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the Standing Rock Indian Reservation (FEMA-4123-DR), dated 06/25/2013. Incident: Severe... adversely affected by the disaster: Primary Area: Standing Rock Indian Reservation. The Interest Rates...

  19. 75 FR 4417 - Wind Cave National Park, Custer County, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... Wind Cave National Park, Custer County, SD AGENCY: National Park Service. ACTION: Notice of... Statement, Wind Cave National Park, Custer County, South Dakota. SUMMARY: Pursuant to Section 102(2)(C) of... Environmental Impact Statement (Plan), Wind Cave National Park, Custer County, South Dakota. On December 3,...

  20. 76 FR 35935 - South Dakota Disaster Number SD-00041

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... From the Federal Register Online via the Government Publishing Office U.S. SMALL BUSINESS ADMINISTRATION South Dakota Disaster Number SD-00041 AGENCY: U.S. Small Business Administration. ACTION... completed loan applications to: U.S. Small Business Administration, Processing and Disbursement...

  1. 76 FR 35936 - South Dakota Disaster Number SD-00041

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... From the Federal Register Online via the Government Publishing Office U.S. SMALL BUSINESS ADMINISTRATION South Dakota Disaster Number SD-00041 AGENCY: U.S. Small Business Administration. ACTION... completed loan applications to: U.S. Small Business Administration, Processing and Disbursement...

  2. 78 FR 29425 - South Dakota Disaster #SD-00057

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00057 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA-4115-DR), dated 05/10/2013. Incident: Severe Winter Storm and...

  3. 76 FR 40767 - South Dakota Disaster Number SD-00041

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... ADMINISTRATION South Dakota Disaster Number SD-00041 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of South Dakota (FEMA-1984-DR), dated 05/13/2011. Incident: Flooding. Incident... Non-Profit organizations in the State of South Dakota, dated 05/13/2011, is hereby amended to...

  4. 75 FR 19435 - South Dakota Disaster Number SD-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    ... ADMINISTRATION South Dakota Disaster Number SD-00027 AGENCY: Small Business Administration. ACTION: Amendment 1... Only for the State of South Dakota (FEMA-1886-DR), dated 03/09/2010. Incident: Severe Winter Storm and... State of South Dakota, dated 03/09/2010, is hereby amended to include the following areas as...

  5. 75 FR 13145 - SOUTH DAKOTA Disaster #SD-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION SOUTH DAKOTA Disaster SD-00027 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA-1886-DR), dated 03/09/2010. Incident: Severe Winter Storm and...

  6. 76 FR 54520 - South Dakota Disaster #SD-00042

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... ADMINISTRATION South Dakota Disaster SD-00042 AGENCY: U.S. Small Business Administration. ACTION: Notice. ] SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of South... Injury Loans Only): South Dakota: Aurora, Bon Homme, Brule, Clay, Dewey, Douglas, Gregory,...

  7. 75 FR 39994 - South Dakota Disaster Number SD-00031

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-13

    ... ADMINISTRATION South Dakota Disaster Number SD-00031 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of South Dakota (FEMA-1915-DR), dated 05/13/2010. Incident: Flooding. Incident... Non-Profit organizations in the State of South Dakota, dated 05/13/2010, is hereby amended to...

  8. 75 FR 28311 - South Dakota Disaster # SD-00031

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00031 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA--1915--DR), dated 05/13/2010. Incident: Flooding. Incident Period:...

  9. 75 FR 61229 - South Dakota Disaster #SD-00034

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00034 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA-1938-DR), dated 09/23/2010. Incident: Severe Storms and Flooding....

  10. 76 FR 30226 - South Dakota Disaster # SD-00041

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00041 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA-1984-DR), dated 05/13/2011. Incident: Flooding. Incident Period:...

  11. 75 FR 30873 - South Dakota Disaster Number SD-00031

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... ADMINISTRATION South Dakota Disaster Number SD-00031 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of South Dakota (FEMA-1915-DR), dated 05/13/2010. Incident: Flooding. Incident... Non-Profit organizations in the State of South Dakota, dated 05/13/2010, is hereby amended to...

  12. 75 FR 38154 - South Dakota Disaster Number SD-00031

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... ADMINISTRATION South Dakota Disaster Number SD-00031 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of SOUTH DAKOTA (FEMA-1915-DR), dated 05/13/2010. Incident: Flooding. Incident... Non-Profit organizations in the State of SOUTH DAKOTA, dated 05/13/2010, is hereby amended...

  13. 75 FR 28312 - South Dakota Disaster # SD-00030

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    2010-05-20

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00030 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA-1914-DR), dated 05/13/2010. Incident: Severe Winter Storm. Incident...

  14. 75 FR 47035 - South Dakota Disaster #SD-00033

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00033 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA-1929-DR), dated 07/29/2010. Incident: Severe storms, tornadoes, and...

  15. 75 FR 69732 - South Dakota Disaster #SD-00035

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00035 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... State of South Dakota (FEMA-1947-DR), dated 11/02/2010. Incident: Severe Storms and Flooding....

  16. 77 FR 46284 - Amendment of Class E Airspace; Lemmon, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Lemmon, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  17. 76 FR 40597 - Amendment of Class E Airspace; Madison, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Madison, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace...

  18. 78 FR 41837 - Establishment of Class E Airspace; Parkston, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Parkston, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class...

  19. 78 FR 48764 - South Dakota Disaster # SD-00061

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION South Dakota Disaster SD-00061 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY...: Submit completed loan applications to: U.S. Small Business Administration, Processing and...

  20. Outcome of Children with Hyperventilation-Induced High-Amplitude Rhythmic Slow Activity with Altered Awareness

    ERIC Educational Resources Information Center

    Barker, Alexander; Ng, Joanne; Rittey, Christopher D. C.; Kandler, Rosalind H.; Mordekar, Santosh R.

    2012-01-01

    Hyperventilation-induced high-amplitude rhythmic slow activity with altered awareness (HIHARS) is increasingly being identified in children and is thought to be an age-related non-epileptic electrographic phenomenon. We retrospectively investigated the clinical outcome in 15 children (six males, nine females) with HIHARS (mean age 7y, SD 1y 11mo;…

  1. Electroencephalographic Abnormalities during Sleep in Children with Developmental Speech-Language Disorders: A Case-Control Study

    ERIC Educational Resources Information Center

    Parry-Fielder, Bronwyn; Collins, Kevin; Fisher, John; Keir, Eddie; Anderson, Vicki; Jacobs, Rani; Scheffer, Ingrid E.; Nolan, Terry

    2009-01-01

    Earlier research has suggested a link between epileptiform activity in the electroencephalogram (EEG) and developmental speech-language disorder (DSLD). This study investigated the strength of this association by comparing the frequency of EEG abnormalities in 45 language-normal children (29 males, 16 females; mean age 6y 11mo, SD 1y 10mo, range…

  2. Effect of Osmotic-Release Oral System Methylphenidate on Different Domains of Attention and Executive Functioning in Children with Attention-Deficit-Hyperactivity Disorder

    ERIC Educational Resources Information Center

    Blum, Nathan J.; Jawad, Abbas F.; Clarke, Angela T.; Power, Thomas J.

    2011-01-01

    Aim: This study investigated whether components of attention and executive functioning improve when children with attention-deficit-hyperactivity disorder (ADHD) are treated with osmotic-release oral system (OROS) methylphenidate. Method: Thirty children (24 males, six females; mean age 8y 6mo, SD 1y 11mo; range 6y 5mo-12y 6mo) with ADHD combined…

  3. Carbon abundances of sdO stars from SPY

    NASA Astrophysics Data System (ADS)

    Hirsch, Heiko; Heber, Uli

    2009-06-01

    Ströer et al. (2007) recently suggested a classification of sdOs according to supersolar and subsolar helium abundances, with only the helium-enriched stars showing signes of carbon and/or nitrogen in their optical spectra. We aim to derive reliable carbon and nitrogen abundances by fitting synthetic spectra to data obtained with the UVES spectrograph at ESO. Here we present our first results of the analysis of carbon abundances in hot subdwarf O stars. By constructing a grid of model atmospheres consisting of hydrogen, helium and carbon we were able to derive atmospheric parameters of nine carbon rich sdOs. We find log(NC/Ntotal) up to ten times higher than the solar value, while the mean value for the effective temperature and the surface gravity is slightly lower than derived by helium-hydrogen models only. Surprisingly, we also find three fast rotators among our program stars.

  4. Shell Model Depiction of Isospin Mixing in sd Shell

    SciTech Connect

    Lam, Yi Hua; Smirnova, Nadya A.; Caurier, Etienne

    2011-11-30

    We constructed a new empirical isospin-symmetry breaking (ISB) Hamiltonian in the sd(1s{sub 1/2}, 0d{sub 5/2} and 0d{sub 3/2}) shell-model space. In this contribution, we present its application to two important case studies: (i){beta}-delayed proton emission from {sup 22}Al and (ii) isospin-mixing correction to superallowed 0{sup +}{yields}0{sup +}{beta}-decay ft-values.

  5. Gray-shading for the SD-4060 graphics device

    NASA Technical Reports Server (NTRS)

    Gloeckler, C.

    1975-01-01

    Grays, a FORTRAN program, is described which will generate gray shading for the SD-4060 graphics device. The program produces 10 shades of gray ranging from no shading at all to complete coverage of the film frame. The graphing capabilities are summarized and illustrated. The figures displayed are representative of the microfilm output, but the distinction between various intensities is much clearer on the film, especially at the more intense shading.

  6. Sex differences in the stress response in SD rats.

    PubMed

    Lu, Jing; Wu, Xue-Yan; Zhu, Qiong-Bin; Li, Jia; Shi, Li-Gen; Wu, Juan-Li; Zhang, Qi-Jun; Huang, Man-Li; Bao, Ai-Min

    2015-05-01

    Sex differences play an important role in depression, the basis of which is an excessive stress response. We aimed at revealing the neurobiological sex differences in the same study in acute- and chronically-stressed rats. Female Sprague-Dawley (SD) rats were randomly divided into 6 groups: chronic unpredictable mild stress (CUMS), acute foot shock (FS) and controls, animals in all 3 groups were sacrificed in proestrus or diestrus. Male SD rats were randomly divided into 3 groups: CUMS, FS and controls. Comparisons were made of behavioral changes in CUMS and control rats, plasma levels of corticosterone (CORT), testosterone (T) and estradiol (E2), and of the hypothalamic mRNA-expression of stress-related molecules, i.e. estrogen receptor α and β, androgen receptor, aromatase, mineralocorticoid receptor, glucocorticoid receptor, corticotropin-releasing hormone, arginine vasopressin and oxytocin. CUMS resulted in disordered estrus cycles, more behavioral and hypothalamic stress-related molecules changes and a stronger CORT response in female rats compared with male rats. Female rats also showed decreased E2 and T levels after FS and CUMS, while male FS rats showed increased E2 and male CUMS rats showed decreased T levels. Stress affects the behavioral, endocrine and the molecular response of the stress systems in the hypothalamus of SD rats in a clear sexual dimorphic way, which has parallels in human data on stress and depression. PMID:25687843

  7. Automated Drusen Segmentation and Quantification in SD-OCT Images

    PubMed Central

    Chen, Qiang; Leng, Theodore; Zheng, Luoluo; Kutzscher, Lauren; Ma, Jeffrey; de Sisternes, Luis; Rubin, Daniel L.

    2013-01-01

    Spectral domain optical coherence tomography (SD-OCT) is a useful tool for the visualization of drusen, a retinal abnormality seen in patients with age-related macular degeneration (AMD); however, objective assessment of drusen is thwarted by the lack of a method to robustly quantify these lesions on serial OCT images. Here, we describe an automatic drusen segmentation method for SD-OCT retinal images, which leverages a priori knowledge of normal retinal morphology and anatomical features. The highly reflective and locally connected pixels located below the retinal nerve fiber layer (RNFL) are used to generate a segmentation of the retinal pigment epithelium (RPE) layer. The observed and expected contours of the RPE layer are obtained by interpolating and fitting the shape of the segmented RPE layer, respectively. The areas located between the interpolated and fitted RPE shapes (which have nonzero area when drusen occurs) are marked as drusen. To enhance drusen quantification, we also developed a novel method of retinal projection to generate an en face retinal image based on the RPE extraction, which improves the quality of drusen visualization over the current approach to producing retinal projections from SD-OCT images based on a summed-voxel projection (SVP), and it provides a means of obtaining quantitative features of drusen in the en face projection. Visualization of the segmented drusen is refined through several post-processing steps, drusen detection to eliminate false positive detections on consecutive slices, drusen refinement on a projection view of drusen, and drusen smoothing. Experimental evaluation results demonstrate that our method is effective for drusen segmentation. In a preliminary analysis of the potential clinical utility of our methods, quantitative drusen measurements, such as area and volume, can be correlated with the drusen progression in non-exudative AMD, suggesting that our approach may produce useful quantitative imaging biomarkers

  8. Semantic description of drama scene by using SD-form

    NASA Astrophysics Data System (ADS)

    Niimi, Michiharu; Kawaguchi, Eiji

    1997-01-01

    Multimedia data processing is becoming more and more a central concern among the people who have been working on image processing. Multimedia database retrieval is one of such a problem. A foreign language study assisting system is a good example for a multimedia data base design. Because each language depends on conversational situation such as topic and speech intention as well as place of conversation.In that case, we can not neglect the semantic aspect of multimedia information. The author's group has already proposed a semantic structure description form, called the SD-form, of the language meaning. They studied the feasibility of its application to natural language generation, story understanding, and conversational text retrieval systems. This paper presents our new attempt to expand our previous system from a text database systems to a multimedia database system which include motion picture, speech sound as well as language text. the source of the data in this project is a series of bilingual TV drama broadcasted in Japan. The most important point is this attempt is that each video scene is described by a set of SD-forms by which scenes are retrieved semantically.

  9. FUSE Observations of He-rich sdB Stars

    NASA Technical Reports Server (NTRS)

    Swiegart, A. V.; Lanz, T.; Brown, T. M.; Hubeny, I.; Landsman, W. B.

    2003-01-01

    Most subdwarf B stars are extremely deficient in helium and selected light elements, but a minority are helium-rich. New evolutionary calculations suggest that these helium-rich sdB stars are the result of a delayed helium-core flash on the white dwarf cooling curve, which leads to extensive mixing between the hydrogen envelope and helium core. Such mixed stars should show greatly enhanced helium and carbon with respect to the other heavy elements. We have recently obtained FUSE spectra of two helium-rich sdB stars, PG1544+488 and JL87, revealing huge C Ill lines at 977 and 1176 A. Our analysis shows that PG1544+488 has a surface composition of 97% He, 2% C, and 1% N, in agreement with the new evolutionary scenario. While JL87 also reveals a large enrichment in carbon and nitrogen (1.4% and 0.4%, respectively), there is still a significant amount of hydrogen in its atmosphere.

  10. Digital LAMP in a sample self-digitization (SD) chip

    PubMed Central

    Herrick, Alison M.; Dimov, Ivan K.; Lee, Luke P.; Chiu, Daniel T.

    2012-01-01

    This paper describes the realization of digital loop-mediated DNA amplification (dLAMP) in a sample self-digitization (SD) chip. Digital DNA amplification has become an attractive technique to quantify absolute concentrations of DNA in a sample. While digital polymerase chain reaction is still the most widespread implementation, its use in resource—limited settings is impeded by the need for thermal cycling and robust temperature control. In such situations, isothermal protocols that can amplify DNA or RNA without thermal cycling are of great interest. Here, we showed the successful amplification of single DNA molecules in a stationary droplet array using isothermal digital loop-mediated DNA amplification. Unlike most (if not all) existing methods for sample discretization, our design allows for automated, loss-less digitization of sample volumes on-chip. We demonstrated accurate quantification of relative and absolute DNA concentrations with sample volumes of less than 2 μl. We assessed the homogeneity of droplet size during sample self-digitization in our device, and verified that the size variation was small enough such that straightforward counting of LAMP-active droplets sufficed for data analysis. We anticipate that the simplicity and robustness of our SD chip make it attractive as an inexpensive and easy-to-operate device for DNA amplification, for example in point-of-care settings. PMID:22399016

  11. Open sd-shell nuclei from first principles

    DOE PAGESBeta

    Jansen, Gustav R.; Signoracci, Angelo J.; Hagen, Gaute; Navratil, Petr

    2016-07-05

    We extend the ab initio coupled-cluster e ective interaction (CCEI) method to open-shell nuclei with protons and neutrons in the valence space, and compute binding energies and excited states of isotopes of neon and magnesium. We employ a nucleon-nucleon and three-nucleon interaction from chiral e ective eld theory evolved to a lower cuto via a similarity renormalization group transformation. We nd good agreement with experiment for binding energies and spectra, while charge radii of neon isotopes are underestimated. For the deformed nuclei 20Ne and 24Mg we reproduce rotational bands and electric quadrupole transitions within uncertainties estimated from an e ectivemore » eld theory for deformed nuclei, thereby demonstrating that collective phenomena in sd-shell nuclei emerge from complex ab initio calculations.« less

  12. Charge radii of neon isotopes across the sd neutron shell

    SciTech Connect

    Marinova, K.; Geithner, W.; Kappertz, S.; Kloos, S.; Kotrotsios, G.; Neugart, R.; Wilbert, S.; Kowalska, M.; Keim, M.; Blaum, K.; Lievens, P.; Simon, H.

    2011-09-15

    We report on the changes in mean square charge radii of unstable neon nuclei relative to the stable {sup 20}Ne, based on the measurement of optical isotope shifts. The studies were carried out using collinear laser spectroscopy on a fast beam of neutral neon atoms. High sensitivity on short-lived isotopes was achieved thanks to nonoptical detection based on optical pumping and state-selective collisional ionization, which was complemented by an accurate determination of the beam kinetic energy. The new results provide information on the structural changes in the sequence of neon isotopes all across the neutron sd shell, ranging from the proton drip line nucleus and halo candidate {sup 17}Ne up to the neutron-rich {sup 28}Ne in the vicinity of the ''island of inversion.'' Within this range the charge radius is smallest for {sup 24}Ne with N=14 corresponding to the closure of the neutron d{sub 5/2} shell, while it increases toward both neutron shell closures, N=8 and N=20. The general trend of the charge radii correlates well with the deformation effects which are known to be large for several neon isotopes. In the neutron-deficient isotopes, structural changes arise from the onset of proton-halo formation for {sup 17}Ne, shell closure in {sup 18}Ne, and clustering effects in {sup 20,21}Ne. On the neutron-rich side the transition to the island of inversion plays an important role, with the radii in the upper part of the sd shell confirming the weakening of the N=20 magic number. The results add new information to the radii systematics of light nuclei where data are scarce because of the small contribution of nuclear-size effects to the isotope shifts which are dominated by the finite-mass effect.

  13. Disilane-based cyclic deposition/etch of Si, Si:P and Si1-yCy:P layers: II. The CDE features

    NASA Astrophysics Data System (ADS)

    Hartmann, J. M.; Benevent, V.; Barnes, J. P.; Veillerot, M.; Prévitali, B.; Batude, P.

    2013-02-01

    We have developed innovative cyclic deposition/etch (CDE) processes in order to grow Si, Si:P and Si1-yCy:P raised sources and drains (RSDs) on patterned wafers. A Si2H6 + PH3 + SiCH6 chemistry was used for the 550 °C growth steps. Meanwhile, the selective etch of poly-crystalline layers on dielectrics was conducted at 600 °C with HCl + GeH4. We have first studied the specifics of those isobaric (P = 20 Torr) CDE processes on bulk, blanket Si(0 0 1) substrates. CDE-grown Si, Si:P and Si1-yCy(:P) layers were high crystalline quality and smooth, although these also contained 2-3% of Ge. Due to the preferential incorporation of P atoms in the lattice, the ‘apparent’ substitutional C content was higher for intrinsic than for in situ phosphorous-doped layers (1.29% versus 1.17% and 1.59% versus 1.47% for the two SiCH6 mass-flows probed). The atomic P concentration in our Si1-yCy:P layers was close to 2.6 × 1020 cm-3, versus 2.1 × 1020 cm-3 in the Si:P layers. The Si, Si:P and Si1-yCy(:P) thickness deposited in each CDE cycle decreased linearly as the HCl+GeH4 etch time increased, with the ‘equivalent’ etch rate (i.e. the slope of this linear decrease) being lower in intrinsic than in in situ doped layers. Higher C contents resulted in lower ‘equivalent’ etch rates. A CDE strategy suppressed the surface roughening occurring for high C content, several tens of nm thick Si1-yCy:P layers grown in one step only. We have then calibrated, for 19-23 nm thick CDE-grown Si, Si:P and Si1-yCy:P RSDs, the HCl + GeH4 etch time per step necessary to achieve full selectivity on patterned silicon-on-insulator substrates. Selectivity was obtained for intrinsic Si once 180 s etch steps were used. Longer etch times were needed for Si:P and especially Si1-yCy:P (270 and 315 s/CDE cycle, respectively). The resulting S/D areas were rather smooth and slightly facetted, but the un-protected poly-Si layers sitting on top of the gate stacks were completely removed with these etch

  14. Improved Hybrid Genome Assemblies of Two Strains of Bacteroides xylanisolvens, SD_CC_1b and SD_CC_2a, Obtained Using Illumina and 454 Sequencing Technologies

    PubMed Central

    Ramaraj, Thiruvarangan; Sundararajan, Anitha; Schilkey, Faye D.; DelVecchio, Vito G.; Donlon, Mildred; Ziemer, Cherie

    2014-01-01

    Bacteroides xlyanisolvens strains (SD_CC_1b, SD_CC_2a) isolated from human feces were grown on crystalline cellulose. Cellulolytic properties are not common in Bacteroides species. Here, we report improved genome sequences of both of the B. xlyanisolvens strains. PMID:24699955

  15. Improved hybrid genome assemblies of 2 strains of Bacteroides xylanisolvens SD-CC-1b and SD-CC-2a using Illumina and 454 sequencing technologies

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Bacteroides xlyanisolvens strains (SD_CC_1b, SD_CC_2a) isolated from human feces were able to grow on crystalline cellulose. Cellulolytic properties are not common in Bacteroides species. Here, we report improved genome sequences of both the B. xlyanisolvens strains....

  16. Elastic-plastic deformations of a beam with the SD-effect

    SciTech Connect

    Pavilaynen, Galina V.

    2015-03-10

    The results for the bending of a cantilever beam with the SD-effect under a concentrated load are discussed. To solve this problem, the standard Bernoulli-Euler hypotheses for beams and the Ilyushin model of perfect plasticity are used. The problem is solved analytically for structural steel A40X. The SD-effect for elastic-plastic deformations is studied. The solutions for beam made of isotropic material and material with the SD-effect are compared.

  17. SD-pair shell model study for {sup 126}Xe and {sup 128}Ba

    SciTech Connect

    Meng Xiangfei; Luo Yanan; Wang, Fu-rong; Pan Feng; Draayer, Jerry P.

    2008-04-15

    The SD-pair shell model is employed to study {sup 126}Xe and {sup 128}Ba. The results show that the spectra and electromagnetic transition strengths can be nicely described in terms of a three-parameter Hamiltonian. In our previous paper, we got a conclusion that the SD-pair approximation improves with the number of SD pairs N. This work shows that this conclusion can be extrapolated to the case with N=5.

  18. Thermal expansion, polarization and phase diagrams of Ba1-yBi2y/3Ti1-xZrxO3 and Ba1-yLayTi1-y/4O3 compounds

    NASA Astrophysics Data System (ADS)

    Gorev, Michail; Bondarev, Vitaly; Flerov, Igor; Maglione, Mario; Simon, Annie; Sciau, Philippe; Boulos, Madona; Guillemet-Fritsch, Sophie

    2009-02-01

    The thermal expansion properties of the ceramic compositions Ba1-yLayTi1-y/4O3 (y = 0.0, 0.026, 0.036, 0.054) and Ba1-yBi2y/3Ti1-xZrxO3 (y = 0.10; x = 0.0, 0.04, 0.05, 0.10, 0.15) were determined in the temperature range 120-700 K. We report the temperature-dependent measurements of the strain, thermal expansion coefficient and the magnitude of root mean square polarization. The results obtained are discussed together with the data on the structure and dielectric properties.

  19. How UV photolysis accelerates the biodegradation and mineralization of sulfadiazine (SD).

    PubMed

    Pan, Shihui; Yan, Ning; Liu, Xinyue; Wang, Wenbing; Zhang, Yongming; Liu, Rui; Rittmann, Bruce E

    2014-11-01

    Sulfadiazine (SD), one of broad-spectrum antibiotics, exhibits limited biodegradation in wastewater treatment due to its chemical structure, which requires initial mono-oxygenation reactions to initiate its biodegradation. Intimately coupling UV photolysis with biodegradation, realized with the internal loop photobiodegradation reactor, accelerated SD biodegradation and mineralization by 35 and 71 %, respectively. The main organic products from photolysis were 2-aminopyrimidine (2-AP), p-aminobenzenesulfonic acid (ABS), and aniline (An), and an SD-photolysis pathway could be identified using C, N, and S balances. Adding An or ABS (but not 2-AP) into the SD solution during biodegradation experiments (no UV photolysis) gave SD removal and mineralization rates similar to intimately coupled photolysis and biodegradation. An SD biodegradation pathway, based on a diverse set of the experimental results, explains how the mineralization of ABS and An (but not 2-AP) provided internal electron carriers that accelerated the initial mono-oxygenation reactions of SD biodegradation. Thus, multiple lines of evidence support that the mechanism by which intimately coupled photolysis and biodegradation accelerated SD removal and mineralization was through producing co-substrates whose oxidation produced electron equivalents that stimulated the initial mono-oxygenation reactions for SD biodegradation. PMID:25199943

  20. On the Components of Segregation Distortion in DROSOPHILA MELANOGASTER. II. Deletion Mapping and Dosage Analysis of the SD Locus

    PubMed Central

    Brittnacher, John G.; Ganetzky, Barry

    1983-01-01

    Segregation distorter (SD) chromosomes are preferentially transmitted to offspring from heterozygous SD/SD+ males owing to the induced dysfunction of the SD+-bearing sperm. This phenomenon involves at least two major loci: the Sd locus whose presence is necessary for distortion to occur and the Rsp locus which acts as the site of Sd action. Several additional loci on SD chromosomes enhance distortion.—In a previous study deletions were used to map the Sd locus and to determine some of its properties. We have extended this analysis with the isolation and characterization of 14 new deletions in the Sd region. From our results we conclude (1) SD chromosomes contain a single Sd locus located in region 37D2-6 of the salivary gland chromosome map. Deletion of this locus in any of three SD chromosomes now studied results in complete loss of ability to distort a sensitive chromosome; (2) the reduced male fecundity observed in many homozygous SD or SDi/SDj combinations is due at least in part to the action of the Sd locus. The fecundity of these males can be substantially increased by deletion of one Sd locus. Thus, it is the presence of two doses of Sd rather than the absence of Sd+ that produces the lowered male fecundity in SD homozygotes; (3) Sd behaves as a neomorph, whereas Sd+, if it exists at all, is amorphic with respect to segregation distortion; (4) these results support a model in which the Sd product is made in limiting amounts and the interaction of this product with the Rsp locus causes sperm dysfunction. The Sd product appears to act preferentially at Rsps (sensitive-Responder) but may also act at Rspi (insensitive-Responder). PMID:17246120

  1. Cytokeratin 8 in Association with sdLDL and ELISA Development

    PubMed Central

    Ashmaig, Mohmed

    2015-01-01

    Background: Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide. Cytokeratins (CKs) which may also be expressed in vascular smooth muscle cells (SMCs) are generally considered to be markers for the differentiation of epithelial cells. Small, dense, low-density lipoprotein (sdLDL) particles, also termed LDL-IV, independently predict risk of CVD. Aims: The aims of this study were to develop an analytical method, apart from ultracentrifugation capable of isolating sdLDL in order to study any associated proteins. Materials and Methods: Using modified gradient gel electrophoresis (GGE), de-identified sdLDL-enriched plasma was used to physically elute and isolate sdLDL particles. To validate the finding, additional plasma from 77 normal and 48 higher risk subjects were used to measure sdLDL particles and CK8. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting method were used to identify the characteristics of proteins associated with sdLDL. An enzyme-linked immunosorbent assay (ELISA) method was developed and validated for the measurement of CK8 in plasma. Results: The validation of the CK8 ELISA method showed good analytical performance. The isolated sdLDL particles were verified with nondenaturing GGE with the apolipoprotein B component confirmed by Western immunoblotting. Confirmed by SDS-PAGE and Western immunoblotting, CK8 was associated with sdLDL. Two-tailed statistical analysis showed that CK8 and sdLDL particles were significantly higher in the high-risk CVD group compared to control group (P < 0.01 and P < 0.01, respectively). Conclusion: This study reports a novel association between CK8 and sdLDL in individuals with CVD who have a predominance of sdLDL. PMID:26713292

  2. Quantum phase transitional patterns in the SD-pair shell model

    SciTech Connect

    Luo Yanan; Meng Xiangfei; Zhang Yu; Pan Feng; Draayer, Jerry P.

    2009-07-15

    Patterns of shape-phase transition in the proton-neutron coupled systems are studied within the SD-pair shell model. The results show that some transitional patterns in the SD-pair shell model are similar to the U(5)-SU(3) and U(5)-SO(6) transitions with signatures of the critical point symmetry of the interacting boson model.

  3. 32. DETAIL OF WALL SHOWN IN SD231. BEHIND WALL FRAMING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. DETAIL OF WALL SHOWN IN SD-2-31. BEHIND WALL FRAMING IS SAMPLING ROOM WITH WOOD SAMPLING ELEVATOR. CRUSHED OXIDIZED ORE BIN ON LEFT (SOUTH). - Bald Mountain Gold Mill, Nevada Gulch at head of False Bottom Creek, Lead, Lawrence County, SD

  4. HOW TO MAKE A SINGLETON sdB STAR VIA ACCELERATED STELLAR EVOLUTION

    SciTech Connect

    Clausen, Drew; Wade, Richard A. E-mail: wade@astro.psu.edu

    2011-06-01

    Many hot subdwarf B stars (sdBs) are in close binaries, and the favored formation channels for subdwarfs rely on mass transfer in a binary system to strip a core He-burning star of its envelope. However, these channels cannot account for sdBs that have been observed in long-period binaries nor the narrow mass distribution of isolated (or 'singleton') sdBs. We propose a new formation channel involving the merger of a helium white dwarf and a low-mass, hydrogen-burning star, which addresses these issues. Hierarchical triples whose inner binaries merge and form sdBs by this process could explain the observed long-period subdwarf+main-sequence binaries. This process would also naturally explain the observed slow rotational speeds of singleton sdBs. We also briefly discuss the implications of this formation channel for extreme horizontal branch morphology in globular clusters and the UV upturn in elliptical galaxies.

  5. Motor coordination, empathy, and social behaviour in school-aged children.

    PubMed

    Cummins, Ariane; Piek, Jan P; Dyck, Murray J

    2005-07-01

    Children with motor coordination problems are known to have emotional difficulties and poor social skills. The current study investigated whether children with poor motor ability have poor emotion recognition skills, and whether these could be linked to problems in social behaviour. It was hypothesized that difficulties in empathic ability might be related to the poor visuo-spatial processing ability identified in children with developmental coordination disorder (as defined by the American Psychiatric Association). The relationship between motor coordination, emotion recognition, and social behaviour was examined in a sample of 234 children (113 males, 121 females; mean age 9y 7mo, [SD 1y 8mo] age range 6y 8mo to 12y 11mo). From this sample two groups of 39 children each (17 females, 22 males), one group with motor difficulties (mean age 9y 11mo [SD 2y], range 6y 11mo to 12y 11mo) and the other of control children (mean age 10y [SD ly 11mo], range 6y 11mo to 12y 11mo), matched for age and sex, were compared using a set of six emotion recognition scales that measured both verbal and perceptual aspects of empathic ability. Children with motor difficulties were found to perform more poorly on scales measuring the ability to recognize static and changing facial expressions of emotion. This difference remained even when visuo-spatial processing was controlled. When controlling for emotion recognition and visuo-spatial organization, a child's motor ability remained a significant predictor of social behaviour. PMID:15991862

  6. Mineralogic variation in drill holes USW NRG-6, NRG-7/7a, SD-7, SD-9, SD-12, and UZ{number_sign}14: New data from 1996--1997 analyses

    SciTech Connect

    Chipera, S.J.; Vaniman, D.T.; Bish, D.L.; Carey, J.W.

    1997-05-30

    New quantitative X-ray diffraction (QXRD) mineralogic data have been obtained for samples from drill holes NRG-6, NRG-7/7A, SD-7, SD-9, SD- 12, and UZ{number_sign}14. In addition, new QXRD analyses were obtained on samples located in a strategic portion of drill hole USW H-3. These data improve our understanding of the mineral stratigraphy at Yucca Mountain, and they further constrain the 3-D Mineralogic Model of Yucca Mountain. Some of the unexpected findings include the occurrence of the zeolite chabazite in the vitric zone of USW SD-7, broad overlap of vitric and zeolitic horizons (over vertical ranges up to 70 m), and the previously unrecognized importance of the bedded tuft beneath the Calico Hills Formation as a subunit with generally more extensive zeolitization than the Calico Hills Formation in the southern part of the potential repository area. Reassessment of data from drill hole USW H-5 suggests that the zeolitization of this bedded unit occurs in the northwestern part of the repository exploration block as well. Further analyses of the same interval in USW H-3, however, have not permitted the same conclusion to be reached for the southwestern part of the repository block because of the much poorer quality of the cuttings in H-3 compared with those from H-5. X-ray fluorescence (XRF) chemical data for drill holes USW SD-7, 9, and 12 show that the zeolitic horizons provide a >10 million year record of retardation of Sr transport, although the data also show that simplistic models of one-dimensional downward flow in the unsaturated zone (UZ) are inadequate. Complex interstratification of zeolites and glass, with highly variable profiles between drill cores, point to remaining problems in constructing detailed mineral stratigraphies. However, the new data in this report provide important information for constructing bounding models of zeolite stratigraphy for transport calculations.

  7. New Mechanism for the Enhancement of sd Dominance in Interacting Boson Models

    NASA Astrophysics Data System (ADS)

    Dukelsky, J.; Pittel, S.

    2001-05-01

    We introduce an exactly solvable model for interacting bosons that extend up to high spin and interact through a repulsive pairing force. The model exhibits a phase transition to a state with almost complete sd dominance. The repulsive pairing interaction that underlies the model has a natural microscopic origin in the Pauli exclusion principle between constituent nucleons. As such, repulsive pairing between bosons seems to provide a new mechanism for the enhancement of sd dominance, giving further support for the validity of the sd interacting boson model.

  8. Purification and characterization of a novel plantaricin, KL-1Y, from Lactobacillus plantarum KL-1.

    PubMed

    Rumjuankiat, Kittaporn; Perez, Rodney Horanda; Pilasombut, Komkhae; Keawsompong, Suttipun; Zendo, Takeshi; Sonomoto, Kenji; Nitisinprasert, Sunee

    2015-06-01

    Three bacteriocins from Lactobacillus plantarum KL-1 were successfully purified using ammonium sulfate precipitation, cation-exchange chromatography and reverse-phase HPLC. The bacteriocin peptides KL-1X, -1Y and -1Z had molecular masses of 3053.82, 3498.16 and 3533.16 Da, respectively. All three peptides were stable at pH 2-12 and 25 °C and at high temperatures of 80 and 100 °C for 30 min and 121 °C for 15 min. However, they differed in their susceptibility to proteolytic enzymes and their inhibition spectra. KL-1Y showed broad inhibitory activities against Gram-positive and Gram-negative bacteria, including Salmonella enterica serovar Enteritidis DMST 17368, Pseudomonas aeruginosa ATCC 15442, P. aeruginosa ATCC 9027, Escherichia coli O157:H7 and E. coli ATCC 8739. KL-1X and -1Z inhibited only Gram-positive bacteria. KL-1X, KL-1Y and KL-1Z exhibited synergistic activity. The successful amino acid sequencing of KL-1Y had a hydrophobicity of approximately 30 % and no cysteine residues suggested its novelty, and it was designated "plantaricin KL-1Y". Plantaricin KL-1Y exhibited bactericidal activity against Bacillus cereus JCM 2152(T). Compared to nisin, KL-1Y displayed broad inhibitory activities of 200, 800, 1600, 800, 400 and 400 AU/mL against the growth of Bacillus coagulans JCM 2257(T), B. cereus JCM 2152(T), Listeria innocua ATCC 33090(T), Staphylococcus aureus TISTR 118, E. coli O157:H7 and E. coli ATCC 8739, respectively, whereas nisin had similar activities against only B. coagulans JCM 2257(T) and B. cereus JCM 2152(T). Therefore, the novel plantaricin KL-1Y is a promising antimicrobial substance for food safety uses in the future. PMID:25862353

  9. PTM-SD: a database of structurally resolved and annotated posttranslational modifications in proteins

    PubMed Central

    Craveur, Pierrick; Rebehmed, Joseph; de Brevern, Alexandre G.

    2014-01-01

    Posttranslational modifications (PTMs) define covalent and chemical modifications of protein residues. They play important roles in modulating various biological functions. Current PTM databases contain important sequence annotations but do not provide informative 3D structural resource about these modifications. Posttranslational modification structural database (PTM-SD) provides access to structurally solved modified residues, which are experimentally annotated as PTMs. It combines different PTM information and annotation gathered from other databases, e.g. Protein DataBank for the protein structures and dbPTM and PTMCuration for fine sequence annotation. PTM-SD gives an accurate detection of PTMs in structural data. PTM-SD can be browsed by PDB id, UniProt accession number, organism and classic PTM annotation. Advanced queries can also be performed, i.e. detailed PTM annotations, amino acid type, secondary structure, SCOP class classification, PDB chain length and number of PTMs by chain. Statistics and analyses can be computed on a selected dataset of PTMs. Each PTM entry is detailed in a dedicated page with information on the protein sequence, local conformation with secondary structure and Protein Blocks. PTM-SD gives valuable information on observed PTMs in protein 3D structure, which is of great interest for studying sequence–structure– function relationships at the light of PTMs, and could provide insights for comparative modeling and PTM predictions protocols. Database URL: PTM-SD can be accessed at http://www.dsimb.inserm.fr/dsimb_tools/PTM-SD/. PMID:24857970

  10. SdPI, The First Functionally Characterized Kunitz-Type Trypsin Inhibitor from Scorpion Venom

    PubMed Central

    Li, Tian; He, Yawen; Ma, Yibao; Chen, Zongyun; Wu, Yingliang; Li, Wenxin; Cao, Zhijian

    2011-01-01

    Background Kunitz-type venom peptides have been isolated from a wide variety of venomous animals. They usually have protease inhibitory activity or potassium channel blocking activity, which by virtue of the effects on predator animals are essential for the survival of venomous animals. However, no Kunitz-type peptides from scorpion venom have been functionally characterized. Principal Findings A new Kunitz-type venom peptide gene precursor, SdPI, was cloned and characterized from a venom gland cDNA library of the scorpion Lychas mucronatus. It codes for a signal peptide of 21 residues and a mature peptide of 59 residues. The mature SdPI peptide possesses a unique cysteine framework reticulated by three disulfide bridges, different from all reported Kunitz-type proteins. The recombinant SdPI peptide was functionally expressed. It showed trypsin inhibitory activity with high potency (Ki = 1.6×10−7 M) and thermostability. Conclusions The results illustrated that SdPI is a potent and stable serine protease inhibitor. Further mutagenesis and molecular dynamics simulation revealed that SdPI possesses a serine protease inhibitory active site similar to other Kunitz-type venom peptides. To our knowledge, SdPI is the first functionally characterized Kunitz-type trypsin inhibitor derived from scorpion venom, and it represents a new class of Kunitz-type venom peptides. PMID:22087336

  11. Characterization of MODIS SD screen vignetting function using observations from spacecraft yaw maneuvers

    NASA Astrophysics Data System (ADS)

    Wang, Zhipeng; Xiong, Xiaoxiong

    2009-08-01

    The MODIS reflective solar bands (RSB) include both the low-gain and high-gain spectral bands depending on their specific applications. MODIS RSBs are calibrated on-orbit by an on-board solar diffuser. In order to avoid detector response saturation when calibrating the high-gain bands, an optional attenuation screen, made of a metal plate with pinhole arrays, is placed in front of the SD panel. Since no pre-launch system-level characterization was made for the SD screen (SDS) vignetting function (VF), a series of spacecraft (Terra and Aqua) yaw maneuvers were carried out to perform on-orbit characterization of the VF. Assuming that the low-gain bands and the high-gain bands have the same VF, the current VF was derived from yaw observations using the MODIS low-gain bands through taking the ratio of their SD responses with and without the SDS in place. In this study, we attempt to characterize the SDS VF directly using detector responses of individual high-gain bands with the SDS in place only. The corresponding SD responses without the SDS, not available from measurements due to saturation, are calculated using detector gains, the SD bi-directional reflectance factor (BRF), and the view geometry that matches the yaw observations with the SDS in place. Results and discussions are focused on the band dependent and detector dependent features of the SDS VF, and their potential impact on the RSB calibration.

  12. The qSD12 Locus Controls Offspring Tissue-Imposed Seed Dormancy in Rice

    PubMed Central

    Gu, Xing-You; Turnipseed, E. Brent; Foley, Michael E.

    2008-01-01

    Seed component structures were grouped into maternal and offspring (embryo and endosperm) tissues to characterize a dormancy quantitative trait locus (QTL) for tissue-specific function using a marker-assisted genetic approach. The approach was devised to test if genotypic/allelic frequencies of a marker tightly linked to the QTL deviate from Mendelian expectations in germinated and nongerminated subpopulations derived from a segregation population of partially after-ripened seeds and was applied to the dormancy QTL qSD12 and qSD7-1 in a nearly isogenic background of rice. Experimental results unambiguously demonstrated that qSD12 functions in the offspring tissue(s) and suggested that qSD7-1 may control dormancy through the maternal tissues. These experiments also provide the first solid evidence that an offspring tissue-imposed dormancy gene contributes to the segregation distortion in a mapping population developed from partially after-ripened seeds and, in part, to the germination heterogeneity of seeds from hybrid plants. Offspring and maternal tissue-imposed dormancy genes express in very early and late stages of the life cycle, respectively, and interact to provide the species with complementary adaptation strategies. The qSD12 locus was narrowed to the region of ∼600 kbp on a high-resolution map to facilitate cloning and marker-assisted selection of the major dormancy gene. PMID:18711220

  13. The Mass of the sdB Primary of the Binary HS 2333+3927

    NASA Astrophysics Data System (ADS)

    Heber, U.; Drechsel, H.; Karl, C.; Østensen, R.; Folkes, S.; Napiwotzki, R.; Altmann, M.; Cordes, O.; Solheim, J.-E.; Voss, B.; Koester, D.

    2005-07-01

    Short period sdB binaries with cool companions are crucial to understand pre-CV evolution, because they will evolve into cataclysmic variables, when the sdB will have left the extended horizontal branch. Recently we discovered the sixth such system, HS 2333+3927, consisting of an sdB star and an M dwarf (period: 0.172 d) with a very strong reflection effect, but no eclipses. The reflection is stronger than in any of the other similar systems which renders a quantitative spectral analysis very difficult because the Balmer line profiles may be disturbed by the reflected light. A spectroscopic analysis results in {Teff} = 36 500 K, log{g} = 5.70, and log (nHe/nH) = -2.15. Mass-radius relations were derived from the results of the analysis of light and radial-velocity curves. Comparison with the mass-radius relation derived from the surface gravity of the sdB star favours a rather low mass of 0.38 M⊙ for the primary. The mass of the companion is 0.29 M⊙. HS 2333+3927 is the only known sdB+dM system with a period above the CV period gap.

  14. Hypertension during chronic exposure to cold: Comparison between Sprague Dawley (SD) and Long Evans (LE) strains

    SciTech Connect

    Riesselmann, A.; Baron, A.; Fregly, M.J. )

    1991-03-11

    Hypertension accompanies chronic exposure of SD rats to cold (5-6C), including elevation of systolic, diastolic, and mean blood pressures and cardiac hypertrophy. The renin-angiotensin system may play an important role. Earlier studies suggested that the LE strain may have a decrease in angiotensin I converting enzyme (ACE) activity. Measurement of ACE activity in plasmas of SE and LE strains revealed that basal activity of ACE in the plasma of the LE strain was significantly less than that of the SD strain. A second study was carried out in which both strains were exposed to cold for 7 weeks. There were clear differences between strains. Rats of the SD strain had a significant elevation in their blood pressure; a significantly increased urinary output of norepinephrine (NE) and epinephrine (E); and significant increases in weights of heart, kidneys, adrenals, and brown adipose tissue (IBAT) compared to their controls maintained at 26C. In contrast, rats of the LE strain were less responsive to cold in that blood pressure failed to rise as sharply and to attain as high a level; NE and E outputs, as well as weights of heart and IBAT were significantly less than those of rats of the cold-treated SD strain. Thus, the lower ACE activity in plasma of LE strain, as well as a reduced secretion of catecholamines, may protect these rats against the rise of blood pressure characteristically observed when rats of the SD strain are exposed to cold.

  15. Electrochromism in sputter deposited W1-y MoyO3 thin films

    NASA Astrophysics Data System (ADS)

    Arvizu, M. A.; Granqvist, C. G.; Niklasson, G. A.

    2016-02-01

    Electrochromic (EC) properties of tungsten-molybdenum oxide (W1-y MoyO3) thin films were investigated. The films were deposited on indium tin oxide covered glass by reactive DC sputtering from tungsten and molybdenum targets. Elemental compositions of the W1-y MoyO3 films were determined by Rutherford back scattering. Voltammetric cycling was performed in an electrolyte of 1 M LiClO4 in propylene carbonate. An increase in molybdenum content in the EC films caused both a shift towards higher energies and a lowering of the maximum of the optical absorption band, as compared with WO3 EC films. Durability under electrochemical cycling was diminished for W1-y MoyO3 EC films.

  16. Defect selective etching of GaAsyP1-y photovoltaic materials

    NASA Astrophysics Data System (ADS)

    Yaung, Kevin Nay; Tomasulo, Stephanie; Lang, Jordan R.; Faucher, Joseph; Lee, Minjoo Larry

    2014-10-01

    Rapid and accurate threading dislocation density (TDD) characterization of direct-gap GaAsyP1-y photovoltaic materials using molten KOH defect selective etching (DSE) is demonstrated. TDDs measured using molten KOH DSE show close agreement with those from both electron beam-induced current mapping and planar view transmission electron microscopy, provided TDD<107 cm-2. H3PO4 DSE is also demonstrated as an accurate method for characterizing TDD of GaP substrates. Taken together, the DSE methods described here enable TDD characterization over large areas (>105 μm2) from substrate to GaAsyP1-y device layer.

  17. Geobacter sp. SD-1 with enhanced electrochemical activity in high-salt concentration solutions.

    PubMed

    Sun, Dan; Call, Douglas; Wang, Aijie; Cheng, Shaoan; Logan, Bruce E

    2014-12-01

    An isolate, designated strain SD-1, was obtained from a biofilm dominated by Geobacter sulfurreducens in a microbial fuel cell. The electrochemical activity of strain SD-1 was compared with type strains, G. sulfurreducens PCA and Geobacter metallireducens GS-15, and a mixed culture in microbial electrolysis cells. SD-1 produced a maximum current density of 290 ± 29 A m−3 in a high-concentration phosphate buffer solution (PBS-H, 200 mM). This current density was significantly higher than that produced by the mixed culture (189 ± 44 A m−3) or the type strains (< 70 A m−3). In a highly saline water (SW; 50 mM PBS and 650 mM NaCl), current by SD-1 (158 ± 4 A m−3) was reduced by 28% compared with 50 mM PBS (220 ± 4 A m−3), but it was still higher than that of the mixed culture (147 ± 19 A m−3), and strains PCA and GS-15 did not produce any current. Electrochemical tests showed that the improved performance of SD-1 was due to its lower charge transfer resistance and more negative potentials produced at higher current densities. These results show that the electrochemical activity of SD-1 was significantly different than other Geobacter strains and mixed cultures in terms of its salt tolerance. PMID:25756125

  18. A New sdO+dM Binary with Extreme Eclipses and Reflection Effect

    NASA Astrophysics Data System (ADS)

    Derekas, A.; Németh, P.; Southworth, J.; Borkovits, T.; Sárneczky, K.; Pál, A.; Csák, B.; Garcia-Alvarez, D.; Maxted, P. F. L.; Kiss, L. L.; Vida, K.; Szabó, Gy. M.; Kriskovics, L.

    2015-08-01

    We report the discovery of a new totally eclipsing binary (R.A. = {06}{{h}}{40}{{m}}{29}{{s}}11; decl. = +38°56‧52″2 J = 2000.0; Rmax = 17.2 mag) with an sdO primary and a strongly irradiated red dwarf companion. It has an orbital period of Porb = 0.187284394(11) day and an optical eclipse depth in excess of 5 mag. We obtained 2 low-resolution classification spectra with GTC/OSIRIS and 10 medium-resolution spectra with WHT/ISIS to constrain the properties of the binary members. The spectra are dominated by H Balmer and He ii absorption lines from the sdO star, and phase-dependent emission lines from the irradiated companion. A combined spectroscopic and light curve analysis implies a hot subdwarf temperature of Teff(spec) = 55,000 ± 3000 K, surface gravity of log g (phot) = 6.2 ± 0.04 (cgs), and a He abundance of {log}(n{He}/n{{H}})=-2.24+/- 0.40. The hot sdO star irradiates the red dwarf companion, heating its substellar point to about 22,500 K. Surface parameters for the companion are difficult to constrain from the currently available data: the most remarkable features are the strong H Balmer and C ii-iii lines in emission. Radial velocity estimates are consistent with the sdO+dM classification. The photometric data do not show any indication of sdO pulsations with amplitudes greater than 7 mmag, and Hα-filter images do not provide evidence for the presence of a planetary nebula associated with the sdO star.

  19. Shell-model study for neutron-rich sd-shell nuclei

    SciTech Connect

    Kaneko, Kazunari; Sun Yang; Mizusaki, Takahiro; Hasegawa, Munetake

    2011-01-15

    The microscopic structure of neutron-rich sd-shell nuclei is investigated by using the spherical-shell model in the sd-pf valence space with the extended pairing plus quadrupole-quadrupole forces accompanied by the monopole interaction (EPQQM). The calculation reproduces systematically the known energy levels for even-even and odd-mass nuclei including the recent data for {sup 43}S, {sup 46}S, and {sup 47}Ar. In particular, the erosion of the N=28 shell closure in {sup 42}Si can be explained. Our EPQQM results are compared with other shell-model calculations with the SDPF-NR and SDPF-U effective interactions.

  20. Epoxy encapsulation of the Cernox™ SD thermometer for measuring the temperature of surfaces in liquid helium

    NASA Astrophysics Data System (ADS)

    Dhuley, R. C.; Van Sciver, S. W.

    2016-07-01

    We describe a procedure to pot a Cernox™ thermometer with the SD package in Stycast epoxy. The potting adapts the thermometer for measuring the temperature of a surface immersed in liquid helium (LHe) and other cryogens. The technique thermally insulates the sensor chip from the cryogen while preserving the surface mounting capability of the SD package. The potting introduced <1% shift in the resistance, <0.5% shift in the calibration at 4.2 K and 77 K, and provided repeatable measurements during thermal cycles between room temperature and 4.2 K.

  1. Initial results from the Solar Dynamic (SD) Ground Test Demonstration (GTD) project at NASA Lewis

    NASA Technical Reports Server (NTRS)

    Shaltens, Richard K.; Boyle, Robert V.

    1995-01-01

    A government/industry team designed, built, and tested a 2 kWe solar dynamic space power system in a large thermal/vacuum facility with a simulated sun at the NASA Lewis Research Center. The Lewis facility provides an accurate simulation of temperatures, high vacuum, and solar flux as encountered in low earth orbit. This paper reviews the goals and status of the Solar Dynamic (SD) Ground Test Demonstration (GTD) program and describes the initial testing, including both operational and performance data. This SD technology has the potential as a future power source for the International Space Station Alpha.

  2. 75 FR 31464 - Certification of the Attorney General; Shannon County, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Certification of the Attorney General; Shannon County, SD In accordance with Section 8 of the Voting Rights Act, 42 U.S.C. 1973f, I hereby certify that in my judgment the appointment of federal observers is necessary to enforce the guarantees of...

  3. AmeriFlux US-SdH Nebraska SandHills Dry Valley

    SciTech Connect

    Arkebauer, Tim J.; Billesbach, Dave

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site US-SdH Nebraska SandHills Dry Valley. Site Description - The Nebraska SandHills Dry Valley tower is located on public land owned by the University of Nebraska-Lincoln. The site is on a research cattle ranch where grazing primarily takes place.

  4. Semi-automatic geographic atrophy segmentation for SD-OCT images

    PubMed Central

    Chen, Qiang; de Sisternes, Luis; Leng, Theodore; Zheng, Luoluo; Kutzscher, Lauren; Rubin, Daniel L.

    2013-01-01

    Geographic atrophy (GA) is a condition that is associated with retinal thinning and loss of the retinal pigment epithelium (RPE) layer. It appears in advanced stages of non-exudative age-related macular degeneration (AMD) and can lead to vision loss. We present a semi-automated GA segmentation algorithm for spectral-domain optical coherence tomography (SD-OCT) images. The method first identifies and segments a surface between the RPE and the choroid to generate retinal projection images in which the projection region is restricted to a sub-volume of the retina where the presence of GA can be identified. Subsequently, a geometric active contour model is employed to automatically detect and segment the extent of GA in the projection images. Two image data sets, consisting on 55 SD-OCT scans from twelve eyes in eight patients with GA and 56 SD-OCT scans from 56 eyes in 56 patients with GA, respectively, were utilized to qualitatively and quantitatively evaluate the proposed GA segmentation method. Experimental results suggest that the proposed algorithm can achieve high segmentation accuracy. The mean GA overlap ratios between our proposed method and outlines drawn in the SD-OCT scans, our method and outlines drawn in the fundus auto-fluorescence (FAF) images, and the commercial software (Carl Zeiss Meditec proprietary software, Cirrus version 6.0) and outlines drawn in FAF images were 72.60%, 65.88% and 59.83%, respectively. PMID:24409376

  5. 76 FR 48120 - Black Hills National Forest, Custer, SD-Mountain Pine Beetle Response Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... Forest Service Black Hills National Forest, Custer, SD--Mountain Pine Beetle Response Project AGENCY...: This project proposes to treat areas newly infested by mountain pine beetles on approximately 325,000...-rocky-mountain-black-hills@fs.fed.us , with ``MPB Response Project'' in the subject line....

  6. Quasicontinuous spectrum of γ rays which feed and depopulate SD in ^194Pb.

    NASA Astrophysics Data System (ADS)

    McNabb, D. P.; Cizewski, J. A.; Ding, K.-Y.; Younes, W.; Khoo, T. L.; Lauritsen, T.; Archer, D. E.; Bauer, R. W.; Becker, J. A.; Bernstein, L. A.; Hauschild, K.; Clark, R. M.; Deleplanque, M. A.; Diamond, R. M.; Fallon, P.; Lee, I. Y.; Macchiavelli, A. O.; Stephens, F. S.; Kelly, W. H.

    1996-10-01

    The mechanism for decay from superdeformed (SD) to ``normal'' (ND) states in ^192Hg results in a large quasicontinuum component which can be fit by a statistical model.(R.G. Henry, et al., Phys. Rev. Lett. 73), 777 (1994). Recent experiments(M.J. Brinkman, et al., Phys. Rev. C53), R1461 (1996); T.L. Khoo, et al., Phys. Rev. Lett. 76, 1583 (1996). have also identified discrete one-step decays from SD to ND states in ^194Pb and ^194Hg which have allowed for the determination of excitation energy and spin of the second wells in these nuclei. We used the ^174Yb(^25Mg,5n) reaction at 130 MeV with a backed target and Gammasphere to study the total spectrum of γ rays in coincidence with the yrast SD band in ^194Pb. The response functions of the detectors were previously determined. The results of the preliminary analysis on the quasicontinuous γ rays which feed and depopulate the yrast SD band will be presented. This work was supported in part by the National Science Foundation and the U.S. Department of Energy.

  7. 78 FR 31430 - Proposed Establishment of Class E Airspace; Wagner, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ...This action proposes to establish Class E airspace at Wagner, SD. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Wagner Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  8. 78 FR 25232 - Proposed Establishment of Class E Airspace; Parkston, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ...This action proposes to establish Class E airspace at Parkston, SD. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Parkston Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  9. 78 FR 49985 - Proposed Establishment of Class E Airspace; Sisseton, SD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ...This action proposes to establish Class E airspace at Sisseton, SD. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Sisseton Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for SIAPs at the...

  10. SD-GIS-based temporal-spatial simulation of water quality in sudden water pollution accidents

    NASA Astrophysics Data System (ADS)

    Zhang, Bo; Qin, Yu; Huang, Mingxiang; Sun, Qiang; Li, Shun; Wang, Liqiang; Yu, Chaohui

    2011-07-01

    System dynamics (SD) is well suited for studying dynamic nonlinear complex systems. In this paper, SD is applied to a rapid-onset water pollution accident using a 1-D water quality model and a conceptual GIS-SD framework is constructed to simulate the temporal-spatial changes of pollutant concentration. Based on the component GIS and the SD model, a prototype system of water quality simulation in water pollution accidents is developed. The data collected on the spot in the Songhua River water pollution accident in November 2005 were used for model parameter calibration and model validation. The results showed that: (1) the constructed model could simulate the changes of nitrobenzene concentration with time in the Songhua River water pollution accident, especially during the peak concentration and at the arrival time of peak concentration, and that the simulated values and the on-the-spot monitored values corresponded with each other well; (2) the scenario simulation could be made by adjusting parameters u (longitudinal current velocity), E (longitudinal diffusion coefficient), and k (decay rate coefficient). Such a model can provide decision makers with quantitative information to optimize related emergency response measures.

  11. High Production of Squalene Using a Newly Isolated Yeast-like Strain Pseudozyma sp. SD301.

    PubMed

    Song, Xiaojin; Wang, Xiaolong; Tan, Yanzhen; Feng, Yingang; Li, Wenli; Cui, Qiu

    2015-09-30

    A yeast-like fungus, termed strain SD301, with the ability to produce a high concentration of squalene, was isolated from Shuidong Bay, China. The nucleotide sequence analysis of the internal transcribed spacer (ITS) region of SD301 indicated the strain belonged to Pseudozyma species. The highest biomass and squalene production of SD301 were obtained when glucose and yeast extracts were used as the carbon and nitrogen sources, respectively, with a C/N ratio of 3. The optimal pH and temperature were 6 and 25 °C, with 15 g L(-1) of supplemented sea salt. The maximum squalene productivity reached 0.039 g L(-1) h(-1) in batch fermentation, while the maximum squalene yield of 2.445 g L(-1) was obtained in fed-batch fermentation. According to our knowledge, this is the highest squalene yield produced thus far using fermentation technology, and the newly isolated strain Pseudozyma sp. SD301 is a promising candidate for commercial squalene production. PMID:26350291

  12. Linear in-wavenumber optical spectrum registration in SD-OCT

    NASA Astrophysics Data System (ADS)

    Gelikonov, Grigory V.; Gelikonov, Valentin M.; Shilyagin, Pavel A.

    2012-01-01

    An efficient technique of linear in-wavenumber optical spectrum registration in SD-OCT is proposed. Methods of partial phase correction of registered optical spectrum for in-wavenumber linearization are described and investigated. The decrease sensitivity decay with depth increasing degeneration is presented. The experimental results for sample media are presented.

  13. 78 FR 24228 - Lake Andes National Wildlife Refuge Complex, Lake Andes, SD; Final Comprehensive Conservation Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... review and comment following the announcement in the Federal Register on October 29, 2012 ] (77 FR 65574... Fish and Wildlife Service Lake Andes National Wildlife Refuge Complex, Lake Andes, SD; Final... conservation plan and finding of no significant impact (FONSI) for the Lake Andes National Wildlife...

  14. Exploring Stellar Evolution Models of sdB Stars using MESA

    NASA Astrophysics Data System (ADS)

    Schindler, Jan-Torge; Green, Elizabeth M.; Arnett, W. David

    2015-06-01

    Stellar evolution calculations have had great success reproducing the observed atmospheric properties of different classes of stars. Recent detections of g-mode pulsations in evolved He burning stars allow a rare comparison of their internal structure with stellar models. Asteroseismology of subdwarf B (sdB) stars suggests convective cores of 0.22-0.28 M⊙, ≳45% of the total stellar mass. Previous studies found significantly smaller convective core masses (≲0.19 M⊙) at a comparable evolutionary stage. We evolved stellar models with Modules for Experiments in Stellar Astrophysics (MESA) to explore how well the interior structures inferred from asteroseismology can be reproduced by standard algorithms. Our qualitative evolutionary paths, position in the log g-{{T}eff} diagram, and model timescales are consistent with previous results. The sdB masses from our full evolutionary sequences fall within the range of the empirical sdB mass distribution, but are nearly always lower than the median. Using standard MLT with atomic diffusion we find convective core masses of ˜0.17-0.18 M⊙, averaged over the entire sdB lifetime. We can increase the convective core sizes to be as large as those inferred from asteroseismology, but only for extreme values of the overshoot parameter (overshoot gives numerically unstable and physically unrealistic behavior at the boundary). High resolution three-dimensional simulations of turbulent convection in stars suggest that the Schwarzschild criterion for convective mixing systematically underestimates the actual extent of mixing because a boundary layer forms. Accounting for this would decrease the errors in both sdB total and convective core masses.

  15. Automated Segmentability Index for Layer Segmentation of Macular SD-OCT Images

    PubMed Central

    Lee, Kyungmoo; Buitendijk, Gabriëlle H.S.; Bogunovic, Hrvoje; Springelkamp, Henriët; Hofman, Albert; Wahle, Andreas; Sonka, Milan; Vingerling, Johannes R.; Klaver, Caroline C.W.; Abràmoff, Michael D.

    2016-01-01

    Purpose To automatically identify which spectral-domain optical coherence tomography (SD-OCT) scans will provide reliable automated layer segmentations for more accurate layer thickness analyses in population studies. Methods Six hundred ninety macular SD-OCT image volumes (6.0 × 6.0 × 2.3 mm3) were obtained from one eyes of 690 subjects (74.6 ± 9.7 [mean ± SD] years, 37.8% of males) randomly selected from the population-based Rotterdam Study. The dataset consisted of 420 OCT volumes with successful automated retinal nerve fiber layer (RNFL) segmentations obtained from our previously reported graph-based segmentation method and 270 volumes with failed segmentations. To evaluate the reliability of the layer segmentations, we have developed a new metric, segmentability index SI, which is obtained from a random forest regressor based on 12 features using OCT voxel intensities, edge-based costs, and on-surface costs. The SI was compared with well-known quality indices, quality index (QI), and maximum tissue contrast index (mTCI), using receiver operating characteristic (ROC) analysis. Results The 95% confidence interval (CI) and the area under the curve (AUC) for the QI are 0.621 to 0.805 with AUC 0.713, for the mTCI 0.673 to 0.838 with AUC 0.756, and for the SI 0.784 to 0.920 with AUC 0.852. The SI AUC is significantly larger than either the QI or mTCI AUC (P < 0.01). Conclusions The segmentability index SI is well suited to identify SD-OCT scans for which successful automated intraretinal layer segmentations can be expected. Translational Relevance Interpreting the quantification of SD-OCT images requires the underlying segmentation to be reliable, but standard SD-OCT quality metrics do not predict which segmentations are reliable and which are not. The segmentability index SI presented in this study does allow reliable segmentations to be identified, which is important for more accurate layer thickness analyses in research and population studies. PMID:27066311

  16. KIC 7668647: a 14 day beaming sdB+WD binary with a pulsating subdwarf

    NASA Astrophysics Data System (ADS)

    Telting, J. H.; Baran, A. S.; Nemeth, P.; Østensen, R. H.; Kupfer, T.; Macfarlane, S.; Heber, U.; Aerts, C.; Geier, S.

    2014-10-01

    The recently discovered subdwarf B (sdB) pulsator KIC 7668647 is one of the 18 pulsating sdB stars detected in the Kepler field. It features a rich g-mode frequency spectrum, with a few low-amplitude p-modes at short periods. This makes it a promising target for a seismic study aiming to constrain the internal structure of this star, and of sdB stars in general. We use new ground-based low-resolution spectroscopy, and the near-continuous 2.88 year Kepler light curve, to reveal that KIC 7668647 consists of a subdwarf B star with an unseen white-dwarf companion with an orbital period of 14.2 d. An orbit with a radial-velocity amplitude of 39 km s-1 is consistently determined from the spectra, from the orbital Doppler beaming seen by Kepler at 163 ppm, and from measuring the orbital light-travel delay of 27 s by timing of the many pulsations seen in the Kepler light curve. The white dwarf has a minimum mass of 0.40 M⊙. We use our high signal-to-noise average spectra to study the atmospheric parameters of the sdB star, and find that nitrogen and iron have abundances close to solar values, while helium, carbon, oxygen and silicon are underabundant relative to the solar mixture. We use the full Kepler Q06-Q17 light curve to extract 132 significant pulsation frequencies. Period-spacing relations and multiplet splittings allow us to identify the modal degree ℓ for the majority of the modes. Using theg-mode multiplet splittings we constrain the internal rotation period at the base of the envelope to 46-48 d as a first seismic result for this star. The few p-mode splittings may point at a slightly longer rotation period further out in the envelope of the star. From mode-visibility considerations we derive that the inclination of the rotation axis of the sdB in KIC 7668647 must be around ~60°. Furthermore, we find strong evidence for a few multiplets indicative of degree 3 ≤ ℓ ≤ 8, which is another novelty in sdB-star observations made possible by Kepler. Based on

  17. Test characteristics of two rapid antigen detection tests (SD FK50 and SD FK60) for the diagnosis of malaria in returned travellers

    PubMed Central

    Van der Palen, Mirna; Gillet, Philippe; Bottieau, Emmanuel; Cnops, Lieselotte; Van Esbroeck, Marjan; Jacobs, Jan

    2009-01-01

    Background Two malaria rapid diagnostic tests were evaluated in a travel clinic setting: the SD FK50 Malaria Ag Plasmodium falciparum test (a two-band test) and the SD FK60 Malaria Ag P. falciparum/Pan test (a three-band test). Methods A panel of stored whole blood samples (n = 452 and n = 614 for FK50 and FK60, respectively) from returned travellers was used. The reference method was microscopy with PCR in case of discordant results. Results For both tests, overall sensitivity for the detection of P. falciparum was 93.5%, reaching 97.6% and 100% at parasite densities above 100 and 1,000/μl respectively. Overall sensitivities for Plasmodium vivax, Plasmodium ovale and Plasmodium malariae for the FK60 test were 87.5%, 76.3% and 45.2%, but they reached 92.6% and 90.5% for P. vivax and P. ovale at parasite densities above 500/μl. Specificities were above 95% for all species and both tests when corrected by PCR, with visible histidine-rich protein-2 lines for P. malariae (n = 3) and P. vivax and P. ovale (1 sample each). Line intensities were reproducible and correlated to parasite densities. The FK60 tests provided clues to estimate parasite densities for P. falciparum below or above 1,000/μl. Conclusion Both the FK50 and FK60 performed well for the diagnosis of P. falciparum in the present setting, and the FK60 for the diagnosis of P. vivax and P. ovale at parasite densities > 500/μl. The potential use of the FK60 as a semi-quantitative estimation of parasite density needs to be further explored. PMID:19416497

  18. 40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Law Constant Less Than 0.1 Y/X Compound name CAS No. Acetaldol 107-89-1 Acetamide 60-35-5...

  19. 40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Law Constant Less Than 0.1 Y/X Compound name CAS No. Acetaldol 107-89-1 Acetamide 60-35-5...

  20. Reducing the artifacts in the identification of outer retinal boundary in the SD-OCT image with inherit retinal dystrophies.

    PubMed

    Min Zhang; Sekiguchi, Hiroyuki; Uji, Akihito; Yakami, Masahiro; Togashi, Kaori

    2015-08-01

    This paper presents a new SD-OCT outer retinal boundary identification method based on the improved graph-theoretic approach in SD-OCT retinal image, which is robust to the image quality degradation and the pathological morphology variability. The performance of the proposed method was verified using the SD-OCT image database with inherit retinal dystrophies, which suffer from the artifacts most among different macular degeneration diseases. The experimental results of the subjective evaluation indicated that the identification results using the proposed method was substantially improved compared with the current built-in software in the SD-OCT devices. PMID:26737258

  1. Chiral magnetic effect and SdH oscillations in Dirac and Weyl metals

    NASA Astrophysics Data System (ADS)

    Kharzeev, Dmitri; Monteiro, Gustavo; Abanov, Alexander

    2015-03-01

    In the present work, we consider the interplay of chiral anomaly and Shubnikov-de Haas (SdH) oscillations in recently discovered Dirac metals. The kinetic theory describing the transport in these new materials should account for the chiral anomaly. The unbalanced number of chiral zero-modes in the presence of magnetic field due to the chiral anomaly gives rise to an additional contribution to the electric current - the chiral magnetic effect. The zero-modes are topologically protected from scattering and their contribution to the current leads to a negative magnetoresistance. This effect was recently observed in measurements on the Dirac semimetal Cd3 As2, where the longitudinal (with respect to magnetic field) component of the resistivity tensor shows a negative slope, along with pronounced Shubnikov-de Haas (SdH) oscillations. We develop a combined description of both these phenomena within a chiral kinetic theory.

  2. HS 2333 + 3927: a new sdB binary with a large reflection effect

    NASA Astrophysics Data System (ADS)

    Karl, C. A.; Heber, U.; Drechsel, H.; Napiwotzki, R.; Altmann, M.; Østensen, R.; Folkes, S.; Solheim, J. E.; Cordes, O.; Voss, B.; Koester, D.

    2004-06-01

    We report the discovery of a binary, HS 2233 + 3927, consisting of an sdB star with a faint companion. From its lightcurve the orbital period of 14,844 s, the mass ratio, the inclination, and other system parameters are derived. The companion does not contribute to the optical light of the system except through a strong reflection effect. The semi-amplitude of the radial velocity curve K 1= 89.6 km/s-1 and a mass function of f(m) = 0.013 M ⊙ are determined. A preliminary spectroscopic analysis of the blue spectra using NLTE model atmospheres results in Teff= 36 500 K, log g= 5.70, and log(n He/n H) =-2.15. These parameters are typical for sdB stars, the companion is probably an M dwarf.

  3. Fragmentation-aware service provisioning for advance reservation multicast in SD-EONs.

    PubMed

    Li, Shengru; Lu, Wei; Liu, Xiahe; Zhu, Zuqing

    2015-10-01

    In this paper, we study the service provisioning schemes for dynamic advance reservation (AR) multicast requests in elastic optical networks (EONs). We first propose several algorithms that can handle the service scheduling and routing and spectrum assignment (RSA) of AR multicast requests jointly, including an integrated two-dimensional fragmentation-aware RSA (2D-FMA) that can alleviate the 2D fragmentation caused by light-tree provisioning. Then, we leverage the idea of software-defined EONs (SD-EONs) that utilizes OpenFlow (OF) in the control plane to demonstrate and evaluate the proposed algorithms. Specifically, we build an SD-EON control plane testbed, implement the algorithms in it, and perform control plane experiments on dynamic AR multicast provisioning. The results indicate that 2D-FMA achieves the best blocking performance and provides the shortest average setup delay. PMID:26480094

  4. Correlations of excited states for sd bosons in the presence of random interactions

    SciTech Connect

    Lei, Y.; Zhao, Y. M.; Yoshida, N.; Arima, A.

    2011-04-15

    In this work we study the yrast states of sd-boson systems in the presence of random interactions. It is found that the yrast states with spin-zero ground states among the random ensemble exhibit strong correlations, characterized by anharmonic vibration, s-boson or d-boson condensation, as well as vibrational and rotational motions. We study these correlations explicitly based on their wave functions and the features of two-body interactions in the random ensemble.

  5. Inversion for Eigenvalues and Modes Using Sierra-SD and ROL.

    SciTech Connect

    Walsh, Timothy; Aquino, Wilkins; Ridzal, Denis; Kouri, Drew Philip

    2015-12-01

    In this report we formulate eigenvalue-based methods for model calibration using a PDE-constrained optimization framework. We derive the abstract optimization operators from first principles and implement these methods using Sierra-SD and the Rapid Optimization Library (ROL). To demon- strate this approach, we use experimental measurements and an inverse solution to compute the joint and elastic foam properties of a low-fidelity unit (LFU) model.

  6. Cation and Vacancy Disorder in U1-yNdyO2.00-X Alloys

    DOE PAGESBeta

    Barabash, Rozaliya I.; Voit, Stewart L.; Aidhy, Dilpuneet S.; Lee, Seung Min; Knight, Travis W.; Sprouster, David J.; Ecker, Lynne E.

    2015-09-14

    In this study, the intermixing and clustering of U/Nd, O, and vacancies were studied by both laboratory and synchrotron-based x-ray diffraction in U1-yNdyO2-X alloys. It was found that an increased holding time at the high experimental temperature during initial alloy preparation results in a lower disorder of the Nd distribution in the alloys. Adjustment of the oxygen concentration in the U1-yNdyO2-X alloys with different Nd concentrations was accompanied by the formation of vacancies on the oxygen sublattice and a nanocrystalline component. The lattice parameters in the U1-yNdyO2-X alloys were also found to deviate significantly from Vegard's law when the Ndmore » concentration was high (53%) and decreased with increasing oxygen concentration. Such changes indicate the formation of large vacancy concentrations during oxygen adjustment at these high temperatures. Finally, the change in the vacancy concentration after the oxygen adjustment was estimated relative to Nd concentration and oxygen stoichiometry.« less

  7. Metabolomics approach to serum biomarker for loperamide-induced constipation in SD rats.

    PubMed

    Kim, Ji-Eun; Lee, Young-Ju; Kwak, Moon-Hwa; Jun, Go; Koh, Eun-Kyoung; Song, Sung-Hwa; Seong, Ji-Eun; Kim, Ji Won; Kim, Kyu-Bong; Kim, Suhkmann; Hwang, Dae-Youn

    2014-03-01

    Loperamide has long been known as an opioid-receptor agonist useful as a drug for treatment of diarrhea resulting from gastroenteritis or inflammatory bowel disease as well as to induce constipation. To determine and characterize putative biomarkers that can predict constipation induced by loperamide treatment, alteration of endogenous metabolites was measured in the serum of Sprague Dawley (SD) rats treated with loperamide for 3 days using (1)H nuclear magnetic resonance ((1)H NMR) spectral data. The amounts and weights of stool and urine excretion were significantly lower in the loperamide-treated group than the No-treated group, while the thickness of the villus, crypt layer, and muscle layer was decreased in the transverse colon of the same group. The concentrations of aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and creatinine (Cr) were also slightly changed in the loperamide-treated group, although most of the serum components were maintained at a constant level. Furthermore, pattern recognition of endogenous metabolites showed completely separate clustering of the serum analysis parameters between the No-treated group and loperamide-treated group. Among 35 endogenous metabolites, four amino acids (alanine, glutamate, glutamine and glycine) and six endogenous metabolites (acetate, glucose, glycerol, lactate, succinate and taurine) were dramatically decreased in loperamide-treated SD rats. These results provide the first data pertaining to metabolic changes in SD rats with loperamide-induced constipation. Additionally, these findings correlate the changes in 10 metabolites with constipation. PMID:24707303

  8. Symmetry of Isoscalar Matrix Elements and Systematics in the sd and beginning of fp shells

    NASA Astrophysics Data System (ADS)

    Orce, J. N.; Petkov, P.; Velázquez, V.; McKay, C. J.; Lesher, S. R.; Choudry, S.; Mynk, M.; Linnemann, A.; Jolie, J.; von Brentano, P.; Werner, V.; Yates, S. W.; McEllistrem, M. T.

    2006-03-01

    A careful determination of the lifetime and measurement of the branching ratio for decay of the first 2T=1+ state in 42Sc has allowed an accurate experimental test of charge independence in the A = 42 isobaric triplet. A lifetime of 69(17) fs was measured at the University of Kentucky, while relative intensities for the 975 keV and 1586 keV transitions depopulating the first 2T=1+ state have been determined at the University of Cologne as 100(1) and 8(1), respectively. Both measurements give an isoscalar matrix element, M0, of 6.4(9) (W.u.)1/2. This result confirms charge independence for the A=42 isobaric triplet. Shell model calculations have been carried out for understanding the global trend of M0 values for A = 4n + 2 isobaric triplets ranging from A = 18 to A = 42. The 21 (T=1)+ → 01 (T=1)+ transition energies, reduced transition probabilities and M0 values are reproduced to a high degree of accuracy. The trend of M0 strength along the sd shell is interpreted in terms of the shell structure. Certain discrepancies arise at the extremes of the sd shell, for the A = 18 and A = 38 isobaric triplets, which might be explained in terms of the low valence space at the extremes of the sd shell.

  9. Geology of the USW SD-12 drill hole Yucca Mountain, Nevada

    SciTech Connect

    Rautman, C.A.; Engstrom, D.A.

    1996-11-01

    Drill hole USW SD-12 is one of several holes drilled under Site Characterization Plan Study 8.3.1.4.3.1, also known as the {open_quotes}Systematic Drilling Program,{close_quotes} as part of the U.S. Department of Energy characterization program at Yucca Mountain, Nevada, which has been proposed as the potential location of a repository for high-level nuclear waste. The SD-12 drill hole is located in the central part of the potential repository area, immediately to the west of the Main Test Level drift of the Exploratory Studies Facility and slightly south of midway between the North Ramp and planned South Ramp declines. Drill hole USW SD-12 is 2166.3 ft (660.26 m) deep, and the core recovered essentially complete sections of ash-flow tuffs belonging to the lower half of the Tiva Canyon Tuff, the Pah Canyon Tuff, and the Topopah Spring Tuff, all of which are part of the Miocene Paintbrush Group. A virtually complete section of the Calico Hills Formation was also recovered, as was core from the entire Prow Pass Tuff formation of the Crater Flat Group.

  10. Metabolomics approach to serum biomarker for loperamide-induced constipation in SD rats

    PubMed Central

    Kim, Ji-Eun; Lee, Young-Ju; Kwak, Moon-Hwa; Jun, Go; Koh, Eun-Kyoung; Song, Sung-Hwa; Seong, Ji-Eun; Kim, Ji Won; Kim, Kyu-Bong; Kim, Suhkmann

    2014-01-01

    Loperamide has long been known as an opioid-receptor agonist useful as a drug for treatment of diarrhea resulting from gastroenteritis or inflammatory bowel disease as well as to induce constipation. To determine and characterize putative biomarkers that can predict constipation induced by loperamide treatment, alteration of endogenous metabolites was measured in the serum of Sprague Dawley (SD) rats treated with loperamide for 3 days using 1H nuclear magnetic resonance (1H NMR) spectral data. The amounts and weights of stool and urine excretion were significantly lower in the loperamide-treated group than the No-treated group, while the thickness of the villus, crypt layer, and muscle layer was decreased in the transverse colon of the same group. The concentrations of aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and creatinine (Cr) were also slightly changed in the loperamide-treated group, although most of the serum components were maintained at a constant level. Furthermore, pattern recognition of endogenous metabolites showed completely separate clustering of the serum analysis parameters between the No-treated group and loperamide-treated group. Among 35 endogenous metabolites, four amino acids (alanine, glutamate, glutamine and glycine) and six endogenous metabolites (acetate, glucose, glycerol, lactate, succinate and taurine) were dramatically decreased in loperamide-treated SD rats. These results provide the first data pertaining to metabolic changes in SD rats with loperamide-induced constipation. Additionally, these findings correlate the changes in 10 metabolites with constipation. PMID:24707303

  11. SD-MSAEs: Promoter recognition in human genome based on deep feature extraction.

    PubMed

    Xu, Wenxuan; Zhang, Li; Lu, Yaping

    2016-06-01

    The prediction and recognition of promoter in human genome play an important role in DNA sequence analysis. Entropy, in Shannon sense, of information theory is a multiple utility in bioinformatic details analysis. The relative entropy estimator methods based on statistical divergence (SD) are used to extract meaningful features to distinguish different regions of DNA sequences. In this paper, we choose context feature and use a set of methods of SD to select the most effective n-mers distinguishing promoter regions from other DNA regions in human genome. Extracted from the total possible combinations of n-mers, we can get four sparse distributions based on promoter and non-promoters training samples. The informative n-mers are selected by optimizing the differentiating extents of these distributions. Specially, we combine the advantage of statistical divergence and multiple sparse auto-encoders (MSAEs) in deep learning to extract deep feature for promoter recognition. And then we apply multiple SVMs and a decision model to construct a human promoter recognition method called SD-MSAEs. Framework is flexible that it can integrate new feature extraction or new classification models freely. Experimental results show that our method has high sensitivity and specificity. PMID:27018214

  12. Symmetry of Isoscalar Matrix Elements and Systematics in the sd and beginning of fp shells

    SciTech Connect

    Orce, J. N.; McKay, C. J.; Lesher, S. R.; Choudry, S.; Mynk, M.; McEllistrem, M. T.; Petkov, P.; Velazquez, V.; Linnemann, A.; Jolie, J.; Brentano, P. von; Werner, V.; Yates, S. W.

    2006-03-13

    A careful determination of the lifetime and measurement of the branching ratio for decay of the first 2{sub T=1}{sup +} state in 42Sc has allowed an accurate experimental test of charge independence in the A = 42 isobaric triplet. A lifetime of 69(17) fs was measured at the University of Kentucky, while relative intensities for the 975 keV and 1586 keV transitions depopulating the first 2{sub T=1}{sup +} state have been determined at the University of Cologne as 100(1) and 8(1), respectively. Both measurements give an isoscalar matrix element, M0, of 6.4(9) (W.u.)1/2. This result confirms charge independence for the A=42 isobaric triplet. Shell model calculations have been carried out for understanding the global trend of M0 values for A = 4n + 2 isobaric triplets ranging from A = 18 to A = 42. The 2{sub 1(T=1)}{sup +} {yields} 0{sub 1(T=1)}{sup +} transition energies, reduced transition probabilities and M0 values are reproduced to a high degree of accuracy. The trend of M0 strength along the sd shell is interpreted in terms of the shell structure. Certain discrepancies arise at the extremes of the sd shell, for the A = 18 and A 38 isobaric triplets, which might be explained in terms of the low valence space at the extremes of the sd shell.

  13. Scientific Use of the Sampler, Drill and Distribution Subsystem (SD2)

    NASA Astrophysics Data System (ADS)

    Armellin, R.; Di Lizia, P.; Crepaldi, M.; Bernelli-Zazzera, F.; Ercoli Finzi, A.

    Rosetta is the third cornerstone mission of the European Space Agency scientific program "Horizon 2000". Rosetta will be the first spacecraft to orbit around a comet nucleus. It was launched in March 2004 and will reach the comet 67P/ChurymovGerasimenko in 2014. A lander (Philae) will be released and land on the comet surface for in-situ investigation. One of the key subsystems of the lander Philae is the Sampler, Drill and Distribution (SD2) subsystem. SD2 provides in-situ operations devoted to soil drilling, samples collection, and their distribution to two evolved gas analyzers (COSAC and PTOLEMY) and one imaging instrument (ÇIVA). Recent studies have proven the existence of a correlation between the drill behavior during perforation and the mechanical characteristics of the cometary soil. This outlines the possibility of using SD2 not only as a tool to support other instruments, but also as a scientific instrument itself. In this paper the possibility of using the drill as a quasi-static penetrator is presented. Within this approach, laboratory tests on glass-foam specimens of different porosity show that the drill behaviour during penetration can be exploited for cometary soil characterization.

  14. Multimodal segmentation of optic disc and cup from stereo fundus and SD-OCT images

    NASA Astrophysics Data System (ADS)

    Miri, Mohammad Saleh; Lee, Kyungmoo; Niemeijer, Meindert; Abràmoff, Michael D.; Kwon, Young H.; Garvin, Mona K.

    2013-03-01

    Glaucoma is one of the major causes of blindness worldwide. One important structural parameter for the diagnosis and management of glaucoma is the cup-to-disc ratio (CDR), which tends to become larger as glaucoma progresses. While approaches exist for segmenting the optic disc and cup within fundus photographs, and more recently, within spectral-domain optical coherence tomography (SD-OCT) volumes, no approaches have been reported for the simultaneous segmentation of these structures within both modalities combined. In this work, a multimodal pixel-classification approach for the segmentation of the optic disc and cup within fundus photographs and SD-OCT volumes is presented. In particular, after segmentation of other important structures (such as the retinal layers and retinal blood vessels) and fundus-to-SD-OCT image registration, features are extracted from both modalities and a k-nearest-neighbor classification approach is used to classify each pixel as cup, rim, or background. The approach is evaluated on 70 multimodal image pairs from 35 subjects in a leave-10%-out fashion (by subject). A significant improvement in classification accuracy is obtained using the multimodal approach over that obtained from the corresponding unimodal approach (97.8% versus 95.2%; p < 0:05; paired t-test).

  15. Automated segmentation of serous pigment epithelium detachment in SD-OCT images

    NASA Astrophysics Data System (ADS)

    Sun, Zhuli; Shi, Fei; Xiang, Dehui; Chen, Haoyu; Chen, Xinjian

    2015-03-01

    Pigment epithelium detachment (PED) is an important clinical manifestation of multiple chorio-retinal disease processes, which can cause the loss of central vision. A 3-D method is proposed to automatically segment serous PED in SD-OCT images. The proposed method consists of five steps: first, a curvature anisotropic diffusion filter is applied to remove speckle noise. Second, the graph search method is applied for abnormal retinal layer segmentation associated with retinal pigment epithelium (RPE) deformation. During this process, Bruch's membrane, which doesn't show in the SD-OCT images, is estimated with the convex hull algorithm. Third, the foreground and background seeds are automatically obtained from retinal layer segmentation result. Fourth, the serous PED is segmented based on the graph cut method. Finally, a post-processing step is applied to remove false positive regions based on mathematical morphology. The proposed method was tested on 20 SD-OCT volumes from 20 patients diagnosed with serous PED. The average true positive volume fraction (TPVF), false positive volume fraction (FPVF), dice similarity coefficient (DSC) and positive predictive value (PPV) are 97.19%, 0.03%, 96.34% and 95.59%, respectively. Linear regression analysis shows a strong correlation (r = 0.975) comparing the segmented PED volumes with the ground truth labeled by an ophthalmology expert. The proposed method can provide clinicians with accurate quantitative information, including shape, size and position of the PED regions, which can assist diagnose and treatment.

  16. Geology of the USW SD-7 drill hole Yucca Mountain, Nevada

    SciTech Connect

    Rautman, C.A.; Engstrom, D.A.

    1996-09-01

    The USW SD-7 drill hole is one of several holes drilled under Site Characterization Plan Study 8.3.1.4.3.1, also known as the Systematic Drilling Program, as part of the U.S. Department of Energy characterization program at Yucca Mountain, Nevada. The Yucca Mountain site has been proposed as the potential location of a repository for high-level nuclear waste. The SD-7 drill hole is located near the southern end of the potential repository area and immediately to the west of the Main Test Level drift of the Exploratory Studies Facility. The hole is not far from the junction of the Main Test Level drift and the proposed South Ramp decline. Drill hole USW SD-7 is 2675.1 ft (815.3 m) deep, and the core recovered nearly complete sections of ash-flow tuffs belonging to the lower half of the Tiva Canyon Tuff, the Pah Canyon Tuff, and the Topopah Spring Tuff, all of which are part of the Miocene Paintbrush Group. Core was recovered from much of the underlying Calico Hills Formation, and core was virtually continuous in the Prow Pass Tuff and the Bullfrog Tuff. The SD-7 drill hole penetrated the top several tens of feet into the Tram Tuff, which underlies the Prow Pass and Bullfrog Tuffs. These latter three units are all formations of the Crater Flat Group, The drill hole was collared in welded materials assigned to the crystal-poor middle nonlithophysal zone of the Tiva Canyon Tuff; approximately 280 ft (85 m) of this ash-flow sheet was penetrated by the hole. The Yucca Mountain Tuff appears to be missing from the section at the USW SD-7 location, and the Pah Canyon Tuff is only 14.5 ft thick. The Pah Canyon Tuff was not recovered in core because of drilling difficulties, suggesting that the unit is entirely nonwelded. The presence of this unit is inferred through interpretation of down-hole geophysical logs.

  17. 40 CFR Table 28 to Subpart G of... - Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 9 2011-07-01 2011-07-01 false Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks 28 Table 28 to Subpart G of Part 63 Protection of Environment ENVIRONMENTAL... (SD) for Internal Floating Roof Tanks Deck construction Typical deck seam length factor...

  18. Complete Genome Sequence of Geobacter anodireducens SD-1T, a Salt-Tolerant Exoelectrogenic Microbe in Bioelectrochemical Systems.

    PubMed

    Sun, Dan; Cheng, Shaoan; Wang, Aijie; Huang, Fangliang; Liu, Wenzong; Xia, Xue

    2016-01-01

    Strain SD-1 is the type strain of the species Geobacter anodireducens, which was originally isolated from a microbial fuel cell reactor in the United States. The characteristic of this bacterium is its high electrochemical activity. Here, we report the fully assembled genome and plasmid sequence of G. anodireducens SD-1(T). PMID:27257213

  19. Complete Genome Sequence of Geobacter anodireducens SD-1T, a Salt-Tolerant Exoelectrogenic Microbe in Bioelectrochemical Systems

    PubMed Central

    Wang, Aijie; Huang, Fangliang; Liu, Wenzong; Xia, Xue

    2016-01-01

    Strain SD-1 is the type strain of the species Geobacter anodireducens, which was originally isolated from a microbial fuel cell reactor in the United States. The characteristic of this bacterium is its high electrochemical activity. Here, we report the fully assembled genome and plasmid sequence of G. anodireducens SD-1T. PMID:27257213

  20. 40 CFR Table 28 to Subpart G of... - Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 10 2012-07-01 2012-07-01 false Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks 28 Table 28 to Subpart G of Part 63 Protection of Environment ENVIRONMENTAL... (SD) for Internal Floating Roof Tanks Deck construction Typical deck seam length factor...

  1. 40 CFR Table 28 to Subpart G of... - Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 10 2014-07-01 2014-07-01 false Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks 28 Table 28 to Subpart G of Part 63 Protection of Environment ENVIRONMENTAL... (SD) for Internal Floating Roof Tanks Deck construction Typical deck seam length factor...

  2. 40 CFR Table 28 to Subpart G of... - Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 10 2013-07-01 2013-07-01 false Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks 28 Table 28 to Subpart G of Part 63 Protection of Environment ENVIRONMENTAL... (SD) for Internal Floating Roof Tanks Deck construction Typical deck seam length factor...

  3. 40 CFR Table 28 to Subpart G of... - Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Deck Seam Length Factors a (SD) for Internal Floating Roof Tanks 28 Table 28 to Subpart G of Part 63 Protection of Environment ENVIRONMENTAL... (SD) for Internal Floating Roof Tanks Deck construction Typical deck seam length factor...

  4. Plasmodium falciparum Rosetting Epitopes Converge in the SD3-Loop of PfEMP1-DBL1α

    PubMed Central

    Angeletti, Davide; Albrecht, Letusa; Blomqvist, Karin; Quintana, María del Pilar; Akhter, Tahmina; Bächle, Susanna M.; Sawyer, Alan; Sandalova, Tatyana; Achour, Adnane; Wahlgren, Mats; Moll, Kirsten

    2012-01-01

    The ability of Plasmodium falciparum parasitized RBC (pRBC) to form rosettes with normal RBC is linked to the virulence of the parasite and RBC polymorphisms that weaken rosetting confer protection against severe malaria. The adhesin PfEMP1 mediates the binding and specific antibodies prevent sequestration in the micro-vasculature, as seen in animal models. Here we demonstrate that epitopes targeted by rosette disrupting antibodies converge in the loop of subdomain 3 (SD3) which connects the h6 and h7 α-helices of PfEMP1-DBL1α. Both monoclonal antibodies and polyclonal IgG, that bound to epitopes in the SD3-loop, stained the surface of pRBC, disrupted rosettes and blocked direct binding of recombinant NTS-DBL1α to RBC. Depletion of polyclonal IgG raised to NTS-DBL1α on a SD3 loop-peptide removed the anti-rosetting activity. Immunizations with recombinant subdomain 1 (SD1), subdomain 2 (SD2) or SD3 all generated antibodies reacting with the pRBC-surface but only the sera of animals immunized with SD3 disrupted rosettes. SD3-sequences were found to segregate phylogenetically into two groups (A/B). Group A included rosetting sequences that were associated with two cysteine-residues present in the SD2-domain while group B included those with three or more cysteines. Our results suggest that the SD3 loop of PfEMP1-DBL1α is an important target of anti-rosetting activity, clarifying the molecular basis of the development of variant-specific rosette disrupting antibodies. PMID:23227205

  5. Correlation between SD-OCT, immunocytochemistry and functional findings in an animal model of retinal degeneration

    PubMed Central

    Cuenca, Nicolás; Fernández-Sánchez, Laura; Sauvé, Yves; Segura, Francisco J.; Martínez-Navarrete, Gema; Tamarit, José Manuel; Fuentes-Broto, Lorena; Sanchez-Cano, Ana; Pinilla, Isabel

    2014-01-01

    Purpose: The P23H rhodopsin mutation is an autosomal dominant cause of retinitis pigmentosa (RP). The degeneration can be tracked using different anatomical and functional methods. In our case, we evaluated the anatomical changes using Spectral-Domain Optical Coherence Tomography (SD-OCT) and correlated the findings with retinal thickness values determined by immunocytochemistry.Methods: Pigmented rats heterozygous for the P23H mutation, with ages between P18 and P180 were studied. Function was assessed by means of optomotor testing and ERGs. Retinal thicknesses measurements, autofluorescence and fluorescein angiography were performed using Spectralis OCT. Retinas were studied by means of immunohistochemistry. Results: Between P30 and P180, visual acuity decreased from 0.500 to 0.182 cycles per degree (cyc/deg) and contrast sensitivity decreased from 54.56 to 2.98 for a spatial frequency of 0.089 cyc/deg. Only cone-driven b-wave responses reached developmental maturity. Flicker fusions were also comparable at P29 (42 Hz). Double flash-isolated rod-driven responses were already affected at P29. Photopic responses revealed deterioration after P29.A reduction in retinal thicknesses and morphological modifications were seen in OCT sections. Statistically significant differences were found in all evaluated thicknesses. Autofluorescence was seen in P23H rats as sparse dots. Immunocytochemistry showed a progressive decrease in the outer nuclear layer (ONL), and morphological changes. Although anatomical thickness measures were significantly lower than OCT values, there was a very strong correlation between the values measured by both techniques.Conclusions: In pigmented P23H rats, a progressive deterioration occurs in both retinal function and anatomy. Anatomical changes can be effectively evaluated using SD-OCT and immunocytochemistry, with a good correlation between their values, thus making SD-OCT an important tool for research in retinal degeneration. PMID:25565976

  6. A complex noise reduction method for improving visualization of SD-OCT skin biomedical images

    NASA Astrophysics Data System (ADS)

    Myakinin, Oleg O.; Zakharov, Valery P.; Bratchenko, Ivan A.; Kornilin, Dmitry V.; Khramov, Alexander G.

    2014-05-01

    In this paper we consider the original method of solving noise reduction problem for visualization's quality improvement of SD-OCT skin and tumors biomedical images. The principal advantages of OCT are high resolution and possibility of in vivo analysis. We propose a two-stage algorithm: 1) process of raw one-dimensional A-scans of SD-OCT and 2) remove a noise from the resulting B(C)-scans. The general mathematical methods of SD-OCT are unstable: if the noise of the CCD is 1.6% of the dynamic range then result distortions are already 25-40% of the dynamic range. We use at the first stage a resampling of A-scans and simple linear filters to reduce the amount of data and remove the noise of the CCD camera. The efficiency, improving productivity and conservation of the axial resolution when using this approach are showed. At the second stage we use an effective algorithms based on Hilbert-Huang Transform for more accurately noise peaks removal. The effectiveness of the proposed approach for visualization of malignant and benign skin tumors (melanoma, BCC etc.) and a significant improvement of SNR level for different methods of noise reduction are showed. Also in this study we consider a modification of this method depending of a specific hardware and software features of used OCT setup. The basic version does not require any hardware modifications of existing equipment. The effectiveness of proposed method for 3D visualization of tissues can simplify medical diagnosis in oncology.

  7. The Mysterious sdO X-ray Binary BD+37°442

    NASA Astrophysics Data System (ADS)

    Heber, U.; Geier, S.; Irrgang, A.; Schneider, D.; Barbu-Barna, I.; Mereghetti, S.; La Palombara, N.

    2014-04-01

    Pulsed X-ray emission in the luminous, helium-rich sdO BD +37°442 has recently been discovered (La Palombara et al. 2012). It was suggested that the sdO star has a neutron star or white dwarf companion with a spin period of 19.2 s. After HD 49798, which has a massive white dwarf companion spinning at 13.2 s in an 1.55 day orbit, this is only the second O-type subdwarf from which X-ray emission has been detected. We report preliminary results of our ongoing campaign to obtain time-resolved high-resolution spectroscopy using the CAFE instrument at Calar Alto observatory and SARG at the Telescopio Nationale Galileo. Atmospheric parameters were derived via a quantitative NLTE spectral analysis. The line fits hint at an unusually large projected rotation velocity. Therefore it seemed likely that BD +37°442 is a binary similar to HD 49798 and that the orbital period is also similar. The level of X-ray emission from BD +37°442 could be explained by accretion from the sdO wind by a neutron star orbiting at a period of less than ten days. Hence, we embarked on radial velocity monitoring in order to derive the binary parameters of the BD+37°442 system and obtained 41 spectra spread out over several month in 2012. Unlike for HD 49798, no radial velocity variations were found and, hence, there is no dynamical evidence for the existence of a compact companion yet. The origin of the pulsed X-ray emission remains as a mystery.

  8. The orbital periods of three sdB eclipsing binary systems

    NASA Astrophysics Data System (ADS)

    Kilkenny, D.

    2014-12-01

    Recent timings of eclipses made between 2011 and 2014 are presented for three binary systems with hot subdwarf primary stars, AA Dor, NY Vir and EC 10246-2707. In the case of AA Dor, the period remains constant. In NY Vir, a rapidly pulsating sdBVr with a cool companion, the period change now appears more complex than can be described by a simple quadratic. EC 10246-2707, which has previously appeared to have a constant period, now appears to be showing a significant period increase. The effect of gravitational radiation in HW Vir-like systems is briefly discussed.

  9. EXOTIME: Searching for planets and measuring \\dot{P} in sdB pulsators

    NASA Astrophysics Data System (ADS)

    Lutz, R.; Schuh, S.; Silvotti, R.

    2012-12-01

    We review the status of the EXOTIME project (EXOplanet search with the TIming MEthod). The two main goals of EXOTIME are to search for sub-stellar companions to sdB stars in wide orbits, and to measure the secular variation of the pulsation periods, which are related to the evolutionary change of the stellar structure. Now, after four years of dense monitoring, we start to see some results and present the brown dwarf and exoplanet candidates V1636 Ori b and DW Lyn b.

  10. ARPES Study on the Strongly Correlated Iron Chalcogenides Fe1+ySexTe1-x

    NASA Astrophysics Data System (ADS)

    Liu, Zhongkai

    2014-03-01

    The level of electronic correlation has been one of the key questions in understanding the nature of iron-based superconductivity. Using Angle Resolved Photoemission Spectroscopy (ARPES), we systematically investigated the correlation level in the iron chalcogenide family Fe1+ySexTe1-x. For the parent compound Fe1.02Te, we discovered ``peak-dip-hump'' spectra with heavily renormalized quasiparticles in the low temperature antiferromagnetic (AFM) state, characteristic of coherent polarons seen in other correlated materials with complex electronic and lattice interactions. As the temperature (or Se ratio x) increases and Fe1.02SexTe1-x is in the paramagnetic (PM) phase, we observed dissociation behavior of polarons, suggestive of connection between the weakening electron-phonon coupling and AFM. Further increase of x leads to an incoherent to coherent crossover in the electronic structure, indicating a reduction in the electronic correlation as the superconductivity emerges. Furthermore, the reduction of the electronic correlation in Fe1+ySexTe1-x evolves in an orbital-dependent way, where the dxy orbital is influenced most significantly. At the other end of the phase diagram (FeSe) where the single crystal is not stable, we have studied the MBE-grown thin film which also reveals orbital-dependent strong correlation in the electronic structure. Our findings provide a quantitative comprehension on the correlation level and its evolution on the phase diagram of Fe1+ySexTe1-x. We discuss the physical scenarios leading to strong correlations and its connection to superconductivity.

  11. Quantum Anomalous Hall Effect in Hg_1-yMn_yTe Quantum Wells

    SciTech Connect

    Liu, Chao-Xing; Qi, Xiao-Liang; Dai, Xi; Fang, Zhong; Zhang, Shou-Cheng; /Stanford U., Phys. Dept.

    2010-03-19

    The quantum Hall effect is usually observed when the two-dimensional electron gas is subjected to an external magnetic field, so that their quantum states form Landau levels. In this work we predict that a new phenomenon, the quantum anomalous Hall effect, can be realized in Hg{sub 1-y}Mn{sub y}Te quantum wells, without the external magnetic field and the associated Landau levels. This effect arises purely from the spin polarization of the Mn atoms, and the quantized Hall conductance is predicted for a range of quantum well thickness and the concentration of the Mn atoms. This effect enables dissipationless charge current in spintronics devices.

  12. Activity in mice of recombinant BCG-EgG1Y162 vaccine for Echinococcus granulosus infection.

    PubMed

    Ma, Xiumin; Zhao, Hui; Zhang, Fengbo; Zhu, Yuejie; Peng, Shanshan; Ma, Haimei; Cao, Chunbao; Xin, Yan; Yimiti, Delixiati; Wen, Hao; Ding, Jianbing

    2016-01-01

    Cystic hydatid disease is a zoonotic parasitic disease caused by Echinococcus granulosus which is distributed worldwide. The disease is difficult to treat with surgery removal is the only cure treatment. In the high endemic areas, vaccination of humans is believed a way to protect communities from the disease. In this study we vaccinated BALB/c mice with rBCG-EgG1Y162, and then detected the level of IgG and IgE specifically against the recombinant protein by ELISA, rBCG-EgG1Y162 induced strong and specific cellular and humoral immune responses. In vitro study showed that rBCG-EgG1Y162 vaccine not only promote splenocytes proliferation but also active T cell. In addition, the rBCG-EgG1Y162 induced a protection in the mice against secondary infection of Echinococcus granulosus. PMID:26266551

  13. HS 0705+6700: a New Eclipsing sdB Binary

    NASA Astrophysics Data System (ADS)

    Drechsel, H.; Heber, U.; Napiwotzki, R.; Ostensen, R.; Solheim, J.-E.; Deetjen, J.; Schuh, S.

    HS 0705+6700 is a newly discovered eclipsing sdB binary system consisting of an sdB primary and a cool secondary main sequence star. CCD photometry obtained in October and November 2000 with the 2.5m Nordic (NOT) telescope (La Palma, Tenerife) in the B passband and with the 2.2m Calar Alto telescope (CAFOS, R filter) yielded eclipse light curves with complete orbital phase coverage at high time resolution. A periodogram analysis of 12 primary minimum times distributed over the time span from October 2000 to March 2001 allowed to derive the following exact period and linear ephemeris: prim. min. = HJD 2451822.759782(22) + 0.09564665(39) ṡ E A total of 15 spectra taken with the 3.5m Calar Alto telescope (TWIN spectrograph) on March 11-12, 2001, were used to establish the radial velocity curve of the primary star (K1 = 85.8 km/s) , and to determine its basic atmospheric parameters (Teff = 29300 K, log g = 5.47). The B and R light curves were solved using our Wilson-Devinney based light curve analysis code MORO (Drechsel et al. 1995, A&A 294, 723). The best fit solution yielded exact system parameters consistent with the spectroscopic results. Detailed results will be published elsewhere (Drechsel et al. 2001, A&A, in preparation).

  14. SdH oscillations and pressure effect of the Weyl semimetal NbAs

    NASA Astrophysics Data System (ADS)

    Luo, Yongkang; Ghimire, N. J.; Wartenbe, M.; Choi, Hongchul; Neupane, M.; McDonald, R. D.; Bauer, E. D.; Zhu, Jianxin; Thompson, J. D.; Ronning, F.

    Via angular Shubnikov-de Hass (SdH) quantum oscillations measurements, we determine the Fermi surface topology of NbAs. The SdH oscillations consist of two frequencies, corresponding to two Fermi surface extrema: 20.8 T (α-pocket) and 15.6 T (β-pocket). The analysis shows that the β-pocket has a Berry phase of π and a small effective mass 0.033 m0, indicative of a nontrivial topology; whereas the α-pocket has a trivial Berry phase of 0 and a heavier effective mass 0.066 m0. Subtle changes can be seen in the ρxx(T) profiles with pressure up to 2.31 GPa. The Fermi surfaces undergo an anisotropic evolution under pressure, while the topological features of the two pockets remain unchanged. Specific heat measurements reveal a small Sommerfeld coefficient γ0 = 0.09(1) mJ/(molK2) and a large Debye temperature, ΘD = 450(9) K, confirming a ``hard'' crystalline lattice that is stable under pressure. We also studied the Kadowaki-Woods ratio of this low-carrier-density massless system, RKW = 3.2×104µ Ω cm mol2K2J-2. After accounting for the small carrier density in NbAs, this RKW indicates a suppressed transport scattering rate relative to other metals.

  15. SdH oscillations and pressure effect of the Weyl semimetal NbAs

    NASA Astrophysics Data System (ADS)

    Luo, Yongkang; Ghimire, N. J.; Wartenbe, M.; Choi, Hongchul; Neupane, M.; McDonald, R. D.; Bauer, E. D.; Zhu, Jianxin; Thompson, J. D.; Ronning, F.

    Via angular Shubnikov-de Hass (SdH) quantum oscillations measurements, we determine the Fermi surface topology of NbAs. The SdH oscillations consist of two frequencies: 20.8 T (α-pocket) and 15.6 T (β-pocket). The analysis shows that the β-pocket has a Berry phase of π and a small effective mass 0.033 m0, indicative of a nontrivial topology; whereas the α-pocket has a trivial Berry phase of 0 and a heavier effective mass 0.066 m0. Subtle changes can be seen in the ρxx(T) profiles with pressure up to 2.31 GPa. The Fermi surfaces undergo an anisotropic evolution under pressure, while the topological features of the two pockets remain unchanged. Specific heat measurements reveal a small Sommerfeld coefficient γ0 = 0.09(1) mJ/(molK2) and a large Debye temperature, ΘD = 450(9) K, confirming a ``hard'' crystalline lattice. The Kadowaki-Woods ratio and a suppressed transport scattering rate are also studied.

  16. An automated framework for 3D serous pigment epithelium detachment segmentation in SD-OCT images

    PubMed Central

    Sun, Zhuli; Chen, Haoyu; Shi, Fei; Wang, Lirong; Zhu, Weifang; Xiang, Dehui; Yan, Chenglin; Li, Liang; Chen, Xinjian

    2016-01-01

    Pigment epithelium detachment (PED) is an important clinical manifestation of multiple chorioretinal diseases, which can cause loss of central vision. In this paper, an automated framework is proposed to segment serous PED in SD-OCT images. The proposed framework consists of four main steps: first, a multi-scale graph search method is applied to segment abnormal retinal layers; second, an effective AdaBoost method is applied to refine the initial segmented regions based on 62 extracted features; third, a shape-constrained graph cut method is applied to segment serous PED, in which the foreground and background seeds are obtained automatically; finally, an adaptive structure elements based morphology method is applied to remove false positive segmented regions. The proposed framework was tested on 25 SD-OCT volumes from 25 patients diagnosed with serous PED. The average true positive volume fraction (TPVF), false positive volume fraction (FPVF), dice similarity coefficient (DSC) and positive predictive value (PPV) are 90.08%, 0.22%, 91.20% and 92.62%, respectively. The proposed framework can provide clinicians with accurate quantitative information, including shape, size and position of the PED region, which can assist clinical diagnosis and treatment. PMID:26899236

  17. The role of glutathione detoxification pathway in MCLR-induced hepatotoxicity in SD rats.

    PubMed

    Li, Shangchun; Chen, Jun; Xie, Ping; Guo, Xiaochun; Fan, Huihui; Yu, Dezhao; Zeng, Cheng; Chen, Liang

    2015-12-01

    In the present study, we investigated the role of glutathione (GSH) and its related enzymes in Sprague Dawley (SD) rats subjected to microcystin-leucine-arginine (MCLR)-induced hepatotoxicity. SD rats were intraperitoneally (i.p.) injected with MCLR after pretreating with or without buthionine-(S,R)-sulfoximine (BSO), an inhibitor of GSH synthesis. The depletion of GSH with BSO enhanced MCLR-induced oxidative stress, resulting in more severe liver damage and higher MCLR accumulation. Similarly, the contents of malondialdehyde (MDA), total GSH (T-GSH), oxidized GSH (GSSG) and GSH were significantly enhanced in BSO pretreated rats following MCLR treatment. The study showed that the transcription of GSH-related enzymes such as glutathione-S-transferase (GST), γ-glutamylcysteine synthetase (γ-GCS), glutathione reductase (GR) varied in different ways (expect for glutathione peroxidase (GPx), whose gene expression was induced in all treated groups) with or without BSO pretreatment before MCLR exposure, suggesting an adaptative response of GSH-related enzymes at transcription level to combat enhancement of oxidative stress induced by MCLR when pretreated with BSO. These data suggested the tissues with low GSH concentration are highly vulnerable to MCLR toxicity and GSH was critical for the detoxification in MCLR-induced hepatotoxicity in vivo. PMID:24964298

  18. Complex dynamics of an archetypal self-excited SD oscillator driven by moving belt friction

    NASA Astrophysics Data System (ADS)

    Zhi-Xin, Li; Qing-Jie, Cao; Léger, Alain

    2016-01-01

    We propose an archetypal self-excited system driven by moving belt friction, which is constructed with the smooth and discontinuous (SD) oscillator proposed by the Cao et al. and the classical moving belt. The moving belt friction is modeled as the Coulomb friction to formulate the mathematical model of the proposed self-excited SD oscillator. The equilibrium states of the unperturbed system are obtained to show the complex equilibrium bifurcations. Phase portraits are depicted to present the hyperbolic structure transition, the multiple stick regions, and the friction-induced asymmetry phenomena. The numerical simulations are carried out to demonstrate the friction-induced vibration of multiple stick-slip phenomena and the stick-slip chaos in the perturbed self-excited system. The results presented here provide an opportunity for us to get insight into the mechanism of the complex friction-induced nonlinear dynamics in mechanical engineering and geography. Project supported by the National Natural Science Foundation of China (Grant Nos. 11372082 and 11572096) and the National Basic Research Program of China (Grant No. 2015CB057405).

  19. FUV, UV, and Optical Observations of the He-sdO Star BD+39 3226

    NASA Astrophysics Data System (ADS)

    Chayer, Pierre; Green, E. M.; Fontaine, G.

    2014-01-01

    Based on observations carried out with the Far Ultraviolet Spectroscopic Explorer, the Space Telescope Imaging Spectrograph, the MMT Observatory, and the Keck telescope HIRES spectrograph, we present a spectral analysis of the He-sdO star BD+39 3226. By fitting the MMT spectrum we obtain a gravity that is 0.7 dex higher than the one reported in the literature. The new atmospheric parameters will have an impact on the measurement of the HI column density toward BD+39 3226, and by this very fact on the deuterium abundance. The high-resolution spectra show stellar absorption lines coming from C, N, O, Si, P, S, Fe, and Ni. The spectra also show lines from heavy elements such as Ge, As, and Sn. On the other hand, neither Zr nor Pb absorption lines are detected. The non-detection of lead in BD+39 3226 indicates that the star does not belong to the newly discovered group of lead-rich He-sdO stars. P.C. is supported by the Canadian Space Agency under a Public Works and Government Services of Canada contract.

  20. A framework for classification and segmentation of branch retinal artery occlusion in SD-OCT

    NASA Astrophysics Data System (ADS)

    Guo, Jingyun; Shi, Fei; Zhu, Weifang; Chen, Haoyu; Chen, Xinjian

    2016-03-01

    Branch retinal artery occlusion (BRAO) is an ocular emergency which could lead to blindness. Quantitative analysis of BRAO region in the retina is very needed to assessment of the severity of retinal ischemia. In this paper, a fully automatic framework was proposed to classify and segment BRAO based on 3D spectral-domain optical coherence tomography (SD-OCT) images. To the best of our knowledge, this is the first automatic 3D BRAO segmentation framework. First, a support vector machine (SVM) based classifier is designed to differentiate BRAO into acute phase and chronic phase, and the two types are segmented separately. To segment BRAO in chronic phase, a threshold-based method is proposed based on the thickness of inner retina. While for segmenting BRAO in acute phase, a two-step segmentation is performed, which includes the bayesian posterior probability based initialization and the graph-search-graph-cut based segmentation. The proposed method was tested on SD-OCT images of 23 patients (12 of acute and 11 of chronic phase) using leave-one-out strategy. The overall classification accuracy of SVM classifier was 87.0%, and the TPVF and FPVF for acute phase were 91.1%, 5.5%; for chronic phase were 90.5%, 8.7%, respectively.

  1. Geology of the USW SD-9 drill hole, Yucca Mountain, Nevada

    SciTech Connect

    Engstrom, D.A.; Rautman, C.A.

    1996-10-01

    Drill hole USW SD-9 is one of several holes drilled under Site Characterization Plan Study as part of the characterization program at Yucca Mountain, Nevada, which has been proposed as the potential location of a repository for high-level nuclear waste. The SD-9 drill hole is located in the northern part of the potential repository area. Quantitative and semiquantitative data are included in this report for cover recovery, rock-quality designation (RQD), lithophysal cavity abundance, and fracturing. These data are spatially variable, both within and among the major formational-level stratigraphic units. Nonwelded intervals in general exhibit higher recoveries and more intact (higher) RQD values than welded intervals. The most intact, highest-RQD materials encountered within the Topopah Spring belong to the lower 33.3 ft of the middle nonlithophysal zone. This report includes quantitative data for the framework material properties of porosity, bulk and particle density, and saturated hydraulic conductivity. Graphical analysis of variations in these laboratory hydrologic properties indicates first-order control of material properties by the degree of welding and the presence of zeolite minerals. Many major lithostratigraphic contacts are not well expressed in the material-property profiles; contacts of material-property units are related more to changes in the intensity of welding. Approximate in-situ saturation data of samples preserved immediately upon recovery from the hole are included in the data tabulation.

  2. Global shear velocity heterogeneities in the D″ layer: Inversion from Sd-SKS differential travel times

    NASA Astrophysics Data System (ADS)

    Kuo, Ban-Yuan; Wu, Kuan-Yi

    1997-06-01

    A global map of shear velocity in the D″ layer results from the inversion of 340 differential travel times of diffracted S(SH) minus SKS(SV) (Sd-SKS), from long-period records of global seismic networks. The two-phase design reduces contamination from upper mantle heterogeneities and errors in location and origin time of the events. Additional corrections are made for (1) azimuthal anisotropy at stations where shear wave splitting parameters are available and for (2) travel time perturbations due to lower mantle asphericity, although both effects are minor compared with the observed residuals with respect to the preliminary reference Earth model (PREM) [Dziewonski and Anderson, 1981]. The corrected residuals, ranging from -16 to 18 s, are attributed to anomalies in D″ sampled by both phases. Taking these residuals as data and assuming a constant, 250-km-thick D″ layer, we invert for a lateral velocity variation model of D″ using spherical harmonics. In parameterizing D″ velocities, a high degree expansion (L=14) avoids aliasing, but only the reliably determined, low degree components (LI

  3. Direct gap Ge1-ySny alloys: Fabrication and design of mid-IR photodiodes

    NASA Astrophysics Data System (ADS)

    Senaratne, C. L.; Wallace, P. M.; Gallagher, J. D.; Sims, P. E.; Kouvetakis, J.; Menéndez, J.

    2016-07-01

    Chemical vapor deposition methods were developed, using stoichiometric reactions of specialty Ge3H8 and SnD4 hydrides, to fabricate Ge1-ySny photodiodes with very high Sn concentrations in the 12%-16% range. A unique aspect of this approach is the compatible reactivity of the compounds at ultra-low temperatures, allowing efficient control and systematic tuning of the alloy composition beyond the direct gap threshold. This crucial property allows the formation of thick supersaturated layers with device-quality material properties. Diodes with composition up to 14% Sn were initially produced on Ge-buffered Si(100) featuring previously optimized n-Ge/i-Ge1-ySny/p-Ge1-zSnz type structures with a single defected interface. The devices exhibited sizable electroluminescence and good rectifying behavior as evidenced by the low dark currents in the I-V measurements. The formation of working diodes with higher Sn content up to 16% Sn was implemented by using more advanced n-Ge1-xSnx/i-Ge1-ySny/p-Ge1-zSnz architectures incorporating Ge1-xSnx intermediate layers (x ˜ 12% Sn) that served to mitigate the lattice mismatch with the Ge platform. This yielded fully coherent diode interfaces devoid of strain relaxation defects. The electrical measurements in this case revealed a sharp increase in reverse-bias dark currents by almost two orders of magnitude, in spite of the comparable crystallinity of the active layers. This observation is attributed to the enhancement of band-to-band tunneling when all the diode layers consist of direct gap materials and thus has implications for the design of light emitting diodes and lasers operating at desirable mid-IR wavelengths. Possible ways to engineer these diode characteristics and improve carrier confinement involve the incorporation of new barrier materials, in particular, ternary Ge1-x-ySixSny alloys. The possibility of achieving type-I structures using binary and ternary alloy combinations is discussed in detail, taking into account

  4. Important operational parameters of membrane bioreactor-sludge disintegration (MBR-SD) system for zero excess sludge production.

    PubMed

    Yoon, Seong-Hoon

    2003-04-01

    In order to prevent excess sludge production during wastewater treatment, a membrane bioreactor-sludge disintegration (MBR-SD) system has been introduced, where the disintegrated sludge is recycled to the bioreactor as a feed solution. In this study, a mathematical model was developed by incorporating a sludge disintegration term into the conventional activated sludge model and the relationships among the operational parameters were investigated. A new definition of F/M ratio for the MBR-SD system was suggested to evaluate the actual organic loading rate. The actual F/M ratio was expected to be much higher than the apparent F/M ratio in MBR-SD. The kinetic parameters concerning the biodegradability of organics hardly affect the system performance. Instead, sludge solubilization ratio (alpha) in the SD process and particulate hydrolysis rate constant (k(h)) in biological reaction determine the sludge disintegration number (SDN), which is related with the overall economics of the MBR-SD system. Under reasonable alpha and k(h) values, SDN would range between 3 and 5 which means the amount of sludge required to be disintegrated would be 3-5 times higher for preventing a particular amount of sludge production. Finally, normalized sludge disintegration rate (q/V) which is needed to maintain a certain level of MLSS in the MBR-SD system was calculated as a function of F/V ratio. PMID:12697235

  5. Absolute density measurement of SD radicals in a supersonic jet at the quantum-noise-limit.

    PubMed

    Mizouri, Arin; Deng, L Z; Eardley, Jack S; Nahler, N Hendrik; Wrede, Eckart; Carty, David

    2013-12-01

    The absolute density of SD radicals in a supersonic jet has been measured down to (1.1 ± 0.1) × 10(5) cm(-3) in a modestly specified apparatus that uses a cross-correlated combination of cavity ring-down and laser-induced fluorescence detection. Such a density corresponds to 215 ± 21 molecules in the probe volume at any given time. The minimum detectable absorption coefficient was quantum-noise-limited and measured to be (7.9 ± 0.6) × 10(-11) cm(-1), in 200 s of acquisition time, corresponding to a noise-equivalent absorption sensitivity for the apparatus of (1.6 ± 0.1) × 10(-9) cm(-1) Hz(-1/2). PMID:24145480

  6. Microsporum fulvum IBRL SD3: as novel isolate for chicken feathers degradation.

    PubMed

    Darah, I; Nur-Diyana, A; Nurul-Husna, S; Jain, K; Lim, Sheh-Hong

    2013-12-01

    Keratinous wastes have increasingly become a problem and accumulate in the environment mainly in the form of feathers, generated mainly from a large number of poultry industries. As keratins are very difficult to degrade by general proteases, they pose a major environmental problem. Therefore, microorganisms which would effectively degrade keratins are needed for recycling such wastes. A geophilic dermatophyte, Microsporum fulvum IBRL SD3 which was isolated from a soil sample collected from a chicken feather dumping site using a baiting technique, was capable to produce keratinase significantly. The crude keratinase was able to degrade whole chicken feathers effectively. The end product of the degradation was protein that contained essential amino acids and may have potential application in animal feed production. Thus, M. fulvum could be a novel organism to produce keratinase for chicken feathers degradation. PMID:24013862

  7. Secondary metabolites from Penicillium pinophilum SD-272, a marine sediment-derived fungus.

    PubMed

    Wang, Ming-Hui; Li, Xiao-Ming; Li, Chun-Shun; Ji, Nai-Yun; Wang, Bin-Gui

    2013-06-01

    Two new secondary metabolites, namely, pinodiketopiperazine A (1) and 6,7-dihydroxy-3-methoxy-3-methylphthalide (2), along with alternariol 2,4-dimethyl ether (3) and L-5-oxoproline methyl ester (4), which were isolated from a natural source for the first time but have been previously synthesized, were characterized from the marine sediment-derived fungus Penicillium pinophilum SD-272. In addition, six known metabolites (5-10) were also identified. Their structures were elucidated by analysis of the NMR and mass spectroscopic data. The absolute configuration of compound 1 was determined by experimental and calculated ECD spectra. Compound 2 displayed potent brine shrimp (Artemia salina) lethality with LD₅₀ 11.2 μM. PMID:23792827

  8. Electrical Characterization of the RCA CDP1822SD Random Access Memory, Volume 1, Appendix a

    NASA Technical Reports Server (NTRS)

    Klute, A.

    1979-01-01

    Electrical characteristization tests were performed on 35 RCA CDP1822SD, 256-by-4-bit, CMOS, random access memories. The tests included three functional tests, AC and DC parametric tests, a series of schmoo plots, rise/fall time screening, and a data retention test. All tests were performed on an automated IC test system with temperatures controlled by a thermal airstream unit. All the functional tests, the data retention test, and the AC and DC parametric tests were performed at ambient temperatures of 25 C, -20 C, -55 C, 85 C, and 125 C. The schmoo plots were performed at ambient temperatures of 25 C, -55 C, and 125 C. The data retention test was performed at 25 C. Five devices failed one or more functional tests and four of these devices failed to meet the expected limits of a number of AC parametric tests. Some of the schmoo plots indicated a small degree of interaction between parameters.

  9. Isospin Symmetry Along The N=Z Line In The sd Shell

    SciTech Connect

    Della Vedova, F.; Lenzi, S. M.; Farnea, E.; Nespolo, M.; Bazzacco, D.; Brandolini, F.; Lunardi, S.; Menegazzo, R.; Rossi Alvarez, C.; Ur, C.A.; Ionescu-Bujor, M.; Bucurescu, D.; Iordachescu, A.; Marginean, N.; De Angelis, G.; Axiotis, M.; Napoli, D. R.; Bizzeti-Sona, A.; Bizzeti, P.G.

    2005-04-05

    Excited states have been studied in sd-shell nuclei following the 16O (70 MeV) + 24Mg (400 {mu}g/cm2) fusion-evaporation reaction. The GASP spectrometer in conjunction with the charged-particle detector ISIS and the Neutron ring allowed the detection of the {gamma}-rays in coincidence with evaporated light particles. New data on the mirror pairs A=31 and A=35 have been obtained. In particular, the comparison between the level schemes of 35Ar and 35Cl has confirmed the importance of the electromagnetic spin-orbit term, which explains the large Mirror Energy Difference values. Evidence of isospin mixing can be deduced from the E1 transitions.

  10. Support vector machine based IS/OS disruption detection from SD-OCT images

    NASA Astrophysics Data System (ADS)

    Wang, Liyun; Zhu, Weifang; Liao, Jianping; Xiang, Dehui; Jin, Chao; Chen, Haoyu; Chen, Xinjian

    2014-03-01

    In this paper, we sought to find a method to detect the Inner Segment /Outer Segment (IS/OS)disruption region automatically. A novel support vector machine (SVM) based method was proposed for IS/OS disruption detection. The method includes two parts: training and testing. During the training phase, 7 features from the region around the fovea are calculated. Support vector machine (SVM) is utilized as the classification method. In the testing phase, the training model derived is utilized to classify the disruption and non-disruption region of the IS/OS, and calculate the accuracy separately. The proposed method was tested on 9 patients' SD-OCT images using leave-one-out strategy. The preliminary results demonstrated the feasibility and efficiency of the proposed method.

  11. Source identification in acoustics and structural mechanics using Sierra/SD.

    SciTech Connect

    Walsh, Timothy Francis; Aquino, Wilkins; Ross, Michael

    2013-03-01

    In this report we derive both time and frequency-domain methods for inverse identification of sources in elastodynamics and acoustics. The inverse/design problem is cast in a PDE-constrained optimization framework with efficient computation of gradients using the adjoint method. The implementation of source inversion in Sierra/SD is described, and results from both time and frequency domain source inversion are compared to actual experimental data for a weapon store used in captive carry on a military aircraft. The inverse methodology is advantageous in that it provides a method for creating ground based acoustic and vibration tests that can reduce the actual number of flight tests, and thus, saving costs and time for the program.

  12. Toxicity of Methylcyclohexane and Its Effect on the Reproductive System in SD Rats

    PubMed Central

    Kang, Min-Gu; Kim, Tae-Gyun; Kang, Chung-Won

    2011-01-01

    Objectives There is limited data regarding the toxicity of methylcyclohexane, despite its wide use in rubber adhesives, paint diluents, and cleansing agents. This study aimed to verify the toxicity and influence on the reproductive system of methylcyclohexane after its repeated injection in Sprague Dawley (SD) rats. Methods Methylcyclohexane was injected subcutaneously into male and female SD rats once a day, five times a week, for 13 weeks at different doses (0, 10, 100, and 1,000 mg/kg/day) for each group. The toxicity of testing material was verified by observing the change in body and organ weight, hematological change, pathological findings, and effect on the reproductive system at each different concentration. Results In the 1,000 mg/kg/day group, there were cases of animal deaths. In animals that survived, hematological changes, including a decrease in the red blood cell count, were observed. A considerable weight gain or loss and pathological abnormalities in the liver, kidney, and other organs were found. However, the 10 and 100 mg/kg/day groups did not cause deaths or other specific abnormalities. In terms of reproductive toxicity, there were changes in hormone levels, including a significant decrease in hormones such as estradiol and progesterone (p < 0.001) in male animals. Menstrual cycle change for female animals did not show concentration dependency. Conclusion When injected repeatedly for 13 weeks, methylcyclohexane proved to be toxic for the liver, heart, and kidney at a high dose. The absolute toxic dose was 1,000 mg/kg/day, while the no observed adverse effect level was less than 100 mg/kg/day. The substance exerted little influence on the reproductive system. PMID:22953213

  13. SAMI3/SD-WACCM-X simulations of ionospheric variability during northern winter 2009

    NASA Astrophysics Data System (ADS)

    McDonald, S. E.; Sassi, F.; Mannucci, A. J.

    2015-09-01

    We have performed simulations using the Naval Research Laboratory's physics-based model of the ionosphere, Sami3 is A Model of the Ionosphere (SAMI3), to illustrate how neutral wind dynamics is responsible for day-to-day variability of the ionosphere. We have used neutral winds specified from the extended version of the specified dynamics Whole Atmosphere Community Climate Model (SD-WACCM-X), in which meteorology below 92 km is constrained by atmospheric specifications from an operational weather forecast model and reanalysis. To assess the realism of the simulations against observations, we have carried out a case study during January-February 2009, a dynamically disturbed time characterized by a sudden stratospheric warming (SSW) commencing 24 January 2009. Model results are compared with total electron content (TEC) from Jet Propulsion Laboratory global ionospheric maps. We show that SAMI3/SD-WACCM-X captures longitudinal variability in the equatorial ionization anomaly associated with nonmigrating tides, with strongest contributions coming from the diurnal eastward wave number 2 (DE2) and DE3. Both migrating and nonmigrating tides contribute to significant day-to-day variability, with TEC varying up to 16%. Our simulation during the SSW period reveals that at the Jicamarca longitude (285°E) on 27 January 2009 nonmigrating tides contribute to an enhancement of the electron density in the morning followed by a decrease in the afternoon. An enhancement of the semidiurnal eastward wave number 2 (SE2) and SE3 nonmigrating tides, likely associated with the appearance of the SSW, suggests that these tides increase the longitudinal variability of the SSW impact on the ionosphere. The conclusion is that realistic meteorology propagating upward from the lower atmosphere influences the dynamo region and reproduces aspects of the observed variability in the ionosphere.

  14. The study of the Oxytropis kansuensis-induced apoptotic pathway in the cerebrum of SD rats

    PubMed Central

    2013-01-01

    Background Locoweeds cause significant livestock poisoning and economic loss all over the world. Animals can develop locoism, a chronic neurological disease, after grazing on locoweeds. Oxytropis kansuensis is a variety of locoweed that contains swainsonine as its main toxic ingredient. The purpose of this study was to investigate the apoptotic pathway induced in the cerebrum by swainsonine. Results Twenty-four Sprague-Dawley rats were randomly divided into four groups (experimental groups I, II, III and a control group) and 6 SD rats of each group were feed in 3 cages separately. Rats were penned as groups and fed with feeds containing 15% (SW content 0.03‰), 30% (SW content 0.06‰), or 45% (SW content 0.09‰) O. kansuensis for experimental groups I, II, and III, respectively, or complete feed in the case of the control group. One hundred and nineteen days after poisoning, and all rats showed neurological disorders at different degrees, which were considered to be successful established a chronic poisoning model of O. kansuensis. rats were sacrificed and the expression of Fas, FasL, Bcl-2, Bax as well as cleaved caspase-3, -8 and -9 proteins in brain tissues were detected by Western blot. The results showed that SW treatment up-regulated Fas and Fas ligand (FasL) (P < 0.05), and that there was an increase in Bax and a decrease in Bcl-2 protein (P < 0.01). Moreover, SW treatment significantly increases the activation of caspase-3, 8 and -9, the key effectors in apoptosis pathway (P < 0.01). Conclusion Our data suggest that SW induces apoptosis in cells of the brain through death receptor and mitochondria-mediated, caspase-dependent apoptotic pathways in the brain tissue of SD rats. PMID:24148892

  15. Lactogenic Activity of an Enzymatic Hydrolysate from Octopus vulgaris and Carica papaya in SD Rats.

    PubMed

    Cai, Bingna; Chen, Hua; Sun, Han; Sun, Huili; Wan, Peng; Chen, Deke; Pan, Jianyu

    2015-11-01

    The traditional Chinese medicine theory believes that octopus papaya soup can stimulate milk production in lactating women. The objective of this study was to determine whether dietary supplementation with an enzymatic hydrolysate of Octopus vulgaris and Carica papaya (EHOC) could increase milk production and nutritional indexes in Sprague Dawley (SD) rats. Female SD rats (n = 24) were fed a control diet (n = 8), EHOC-supplemented diet, or a positive control diet (Shengruzhi) from day 10 of pregnancy to day 10 of lactation. Maternal serum, mammary gland (day 10 of lactation), milk, and pup weight (daily) were collected for analysis. Results showed that the EHOC diet obviously elevated daily milk yield and pup weight compared to the control group (P < .05). The EHOC diet was found to increase the concentration of prolactin (PRL), progesterone (P), estradiol (E2), and growth hormone (GH) significantly in the circulation and mammary gland. Mammary glands of EHOC-treated dams showed clear lobuloalveolar development and proliferation of myoepithelial cells, but no striking variations were observed among the groups. Furthermore, the nutrition content and immune globulin concentration in the milk of EHOC-supplemented dams were higher than those of the control group, especially the cholesterol, glucose, and IgG were higher by 44.98% (P < .001), 42.76% (P < .01), and 42.23% (P < .01), respectively. In conclusion, this article demonstrates that EHOC administration has beneficial effects on milk production in the dams and on performance of the dam and pup. These results indicate that EHOC could be explored as a potentially lactogenic nutriment for lactating women. PMID:26270883

  16. Local Variability of Macular Thickness Measurements With SD-OCT and Influencing Factors

    PubMed Central

    Miraftabi, Arezoo; Amini, Navid; Gornbein, Jeff; Henry, Sharon; Romero, Pablo; Coleman, Anne L.; Caprioli, Joseph; Nouri-Mahdavi, Kouros

    2016-01-01

    Purpose To compare the intrasession variability of spectral-domain optical coherence tomography (SD-OCT)-derived local macular thickness measures and explore influencing factors. Methods One hundred two glaucomatous eyes (102 patients) and 21 healthy eyes (21 subjects) with three good quality macular images during the same session were enrolled. Thickness measurements were calculated for 3° superpixels for the inner plexiform (IPL), ganglion cell (GCL), or retinal nerve fiber layers (mRNFL), GC/IPL, ganglion cell complex, and full macular thickness. Spatial distribution and magnitude of measurement errors (ME; differences between the 3 individual superpixel values and their mean) and association between MEs and thickness, age, axial length, and image quality were explored. Results MEs had a normal distribution with mostly random noise along with a small fraction of outliers (1.2%–6.6%; highest variability in mRNFL and on the nasal border) based on M-estimation. Boundaries of 95% prediction intervals for variability reached a maximum of 3 μm for all layers and diagnostic groups after exclusion of outliers. Correlation between proportion of outliers and thickness measures varied among various parameters. Age, axial length, or image quality did not influence MEs (P > 0.05 for both groups). Conclusions Local variability of macular SD-OCT measurements is low and uniform across the macula. The relationship between superpixel thickness and outlier proportion varied as a function of the parameter of interest. Translational Relevance Given the low and uniform variability within and across eyes, definition of an individualized ‘variability space' seems unnecessary. The variability measurements from this study could be used for designing algorithms for detection of glaucoma progression. PMID:27486555

  17. Thermoelectric properties of indium doped PbTe{sub 1-y}Se{sub y} alloys

    SciTech Connect

    Bali, Ashoka; Mallik, Ramesh Chandra; Wang, Heng; Snyder, G. Jeffrey

    2014-07-21

    Lead telluride and its alloys are well known for their thermoelectric applications. Here, a systematic study of PbTe{sub 1-y}Se{sub y} alloys doped with indium has been done. The powder X-Ray diffraction combined with Rietveld analysis confirmed the polycrystalline single phase nature of the samples, while microstructural analysis with scanning electron microscope results showed densification of samples and presence of micrometer sized particles. The temperature dependent transport properties showed that in these alloys, indium neither pinned the Fermi level as it does in PbTe, nor acted as a resonant dopant as in SnTe. At high temperatures, bipolar effect was observed which restricted the zT to 0.66 at 800 K for the sample with 30% Se content.

  18. Thermal expansivity of Ge{sub 1-y}Sn{sub y} alloys

    SciTech Connect

    Roucka, R.; Fang, Y.-Y.; Kouvetakis, J.; Chizmeshya, A. V. G.; Menendez, J.

    2010-06-15

    The temperature dependence of the lattice parameter of Ge{sub 1-y}Sn{sub y} alloys deposited on Si substrates has been determined from an analysis of their x-ray reciprocal-space maps. It is found that over the range 0

  19. Nonuniform paramagnetic state in nonstoichiometric lanthanum manganites La1- x Mn1- y O3

    NASA Astrophysics Data System (ADS)

    Arbuzova, T. I.; Naumov, S. V.

    2016-06-01

    The magnetic properties of nonstoichiometric lanthanum manganites La1- x Mn1- y O3 have been studied in the temperature range 80 K < T < 650 K. The Curie temperature T C changes nonmonotonically as the number of Mn4+ ions increases. In the paramagnetic region, there exist isolated Mn ions and magnetic polarons which can be conserved to T ⩽ 4 T C, independent of the lattice symmetry. In the T C < T < T pol region, the temperature dependences of the magnetic susceptibility are nonlinear and can be described by the Curie law with a temperature-dependent Curie constant C. The sample has been prepared having a composition near the O' → O structural transition; the spontaneous magnetization of the sample at T ⩽ 1.6 T C is associated to correlated polarons forming due to the double exchange in chains of the E-type antiferromagnetic phase.

  20. Ferro-Orbital Ordering Transition in Iron Telluride Fe1+yTe

    SciTech Connect

    Fobes, David; Zalinznyak, I.; Xu, Zhijun; Zhong, Ruidan; Gu, Genda; Tranquada, John M.; Harriger, Leland W.; Singh, D. K.; Garlea, Vasile O; Lumsden, Mark D; Winn, Barry L

    2014-01-01

    Fe1+yTe with y 0.05 exhibits a first-order phase transition on cooling to a state with a lowered structural symmetry, bicollinear antiferromagnetic order, and metallic conductivity, d /dT > 0. Here, we study samples with y = 0.09(1), where the frustration effects of the interstitial Fe decouple different orders, leading to a sequence of transitions. While the lattice distortion is closely followed by incommensurate magnetic order, the development of bicollinear order and metallic electronic coherence is uniquely associated with a separate hysteretic first-order transition, at a markedly lower temperature, to a phase with dramatically enhanced bond-order wave (BOW) order. The BOW state suggests ferro-orbital ordering, where electronic delocalization in ferromagnetic zigzag chains decreases local spin and results in metallic transport

  1. Interfacial solid-state reaction at thermally oxidized In1 - xGaxAsyP1 - y alloys

    NASA Astrophysics Data System (ADS)

    Kubo, Minoru; Sasai, Yoichi; Ogura, Mototsugu; Kohiki, Shigemi

    1988-07-01

    The interfacial reaction between thermally oxidized In1-xGaxAsyP1-y and an In1-xGaxAsyP1-y epilayer was studied using Raman and x-ray photoelectron spectroscopy (XPS) analyses. In Raman spectra, it was found that the appearance of the phonon modes, i.e., the first-order longitudinal (LO) and transverse-optical (TO) modes for crystalline arsenic, was due to the In1-xGaxAsyP1-y -oxide interfacial reaction. The XPS analyses showed that this reaction corresponded to the GaAs-oxide interfacial reaction, i.e., As2O3+2GaAs→Ga2O3+4As. Furthermore, the reaction depends on the composition y of In1-xGaxAsyP1-y, which may be due to the enhancement in the initial transient reaction by thermal damage of In1-xGaxAsyP1-y occurring at the interface.

  2. Evaluation of SD-208, a TGF-β-RI Kinase Inhibitor, as an Anticancer Agent in Retinoblastoma.

    PubMed

    Fadakar, Puran; Akbari, Abolfazl; Ghassemi, Fariba; Mobini, Gholam Reza; Mohebi, Masoumeh; Bolhassani, Manzar; Abed Khojasteh, Hoda; Heidari, Mansour

    2016-06-01

    Retinoblastoma is the most common intraocular tumor in children resulting from genetic alterations and transformation of mature retinal cells. The objective of this study was to investigate the effects of SD-208, TGF-β-RI kinase inhibitor, on the expression of some miRNAs including a miR-17/92 cluster in retinoblastoma cells. Prior to initiate this work, the cell proliferation was studied by Methyl Thiazolyl Tetrazolium (MTT) and bromo-2'-deoxyuridine (BrdU) assays. Then, the expression patterns of four miRNAs (18a, 20a, 22, and 34a) were investigated in the treated SD-208 (0.0, 1, 2 and 3 µM) and untreated Y-79 cells. A remarkable inhibition of the cell proliferation was found in Y-79 cells treated with SD-208 versus untreated cells. Also, the expression changes were observed in miRNAs 18a, 20a, 22 and 34a in response to SD-208 treatment (P<0.05). The findings of the present study suggest that the anti-cancer effect of SD-208 may be exerted due to the regulation of specific miRNAs, at least in this particular retinoblastoma cell line. To the best of the researchers' knowledge, this is the first report demonstrating that the SD-208 could alter the expression of tumor suppressive miRNAs as well as oncomiRs in vitro. In conclusion, the present data suggest that SD-208 could be an alternative agent in retinoblastoma treatment. PMID:27306340

  3. Refractive Error and Ocular Parameters: Comparison of Two SD-OCT Systems

    PubMed Central

    Ostrin, Lisa A.; Yuzuriha, Jill; Wildsoet, Christine F.

    2015-01-01

    Purpose Spectral domain optical coherence tomography (SD-OCT) was used to examine the influence of refractive error (RE) on foveal retinal and choroidal thicknesses and scleral canal width (SCW). The performance of the Cirrus and Bioptigen SD-OCT instruments was compared in the same eyes. Methods Both eyes of forty healthy human subjects, ages 22 to 38 years, were dilated and imaged, with the Cirrus OCT, using 6 mm 5-line rasters collapsed into one line, one centered on the fovea and one bisecting the optic nerve head. Seventy-two of the same eyes were imaged with the Bioptigen OCT, using 6 mm × 6 mm scans, one centered on the fovea and one on the optic nerve head. Subfoveal retinal and choroidal thicknesses and SCW were measured. Axial lengths (AL) and REs were obtained using an IOLMaster and a Grand Seiko autorefractor, respectively. Results Only right eyes were included in analyses. Spherical equivalent REs ranged from −12.18 to +8.12 D (mean: −3.44 ± 4.06 D), and ALs ranged from 20.56 to 29.17 mm (mean: 24.86 ± 1.91 mm). Myopia was associated with relatively thin choroids at the fovea (p<0.05) but normal retinal thickness. SCW was significantly correlated with AL as measured with the Bioptigen OCT (p<0.05). Retinal and choroidal thicknesses recorded with the Bioptigen OCT tended to be smaller than values obtained with the Cirrus OCT (mean difference: 5.63 and 24.76 µm, respectively), while the converse was true for the SCW (mean difference: 25.45 µm). Conclusions The finding that high myopes tend to have a thinner subfoveal choroid is consistent with previous studies. That high myopia was linked to enlarged scleral canals may help to explain the increased risk of glaucoma in myopia. Observed differences obtained with the Cirrus and Bioptigen instruments urge caution in comparing results collected with different instruments. PMID:25785537

  4. Intravenous Toxicity Study of Water-soluble Ginseng Pharmacopuncture in SD Rats

    PubMed Central

    Yu, Jun-Sang; Sun, Seung-Ho; Lee, Kwang-Ho; Kwon, Ki-Rok

    2015-01-01

    Objectives: Radix Ginseng has been used for thousands of years to treat a wide variety of diseases. Radix ginseng has also been used as a traditional medicine for boosting Qi energy and tonifying the spleen and lungs. Traditionally, its effect could be obtained orally. Nowadays, a new method, the injection of herbal medicine, is being used. This study was performed to investigate the single-dose intravenous toxicity of water-soluble ginseng pharmacopuncture (WSGP) in Sprague-Dawley (SD) rats. Methods: All experiments were carried out at Biotoxtech, an institute authorized to perform non-clinical studies under the regulation of Good Laboratory Practice (GLP). At the age of six weeks, 40 SD rats, 20 male rats and 20 female rats, were allocated into one of 4 groups according to the dosages they would receive. The WSGP was prepared in the Korean Pharmacopuncture Institute under the regulation of Korea-Good Manufacturing Practice (K-GMP). Dosages of WSGP were 0.1, 0.5 and 1.0 mL/animal for the experimental groups, and normal saline was administered to the control group. The rat's general conditions and body weights, the results of their hematological and biochemistry tests, and their necropsy and histopathological findings were investigated to identify the toxicological effect of WSGP injected intravenously. The effect was examined for 14 days after the WSGP injection. This study was performed under the approval of the Institutional Animal Ethics Committee of Biotoxtech. Results: No deaths were found in this single-dose toxicity test on the intravenous injection of WSGP, and no significant changes in the rat's general conditions and body weights, the results on their hematological and biochemistry test, and their necropsy findings were observed during the test. The local area of the injection site showed minial change. The lethal dose was assumed to be over 1.0 mL/animal in both sexes. Conclusion: These results indicate that WSGP is safe at dosages up to 1 m

  5. Low-temperature phase diagram of Fe1+yTe studied using x-ray diffraction

    NASA Astrophysics Data System (ADS)

    Koz, Cevriye; Rößler, Sahana; Tsirlin, Alexander A.; Wirth, Steffen; Schwarz, Ulrich

    2013-09-01

    We used low-temperature synchrotron x-ray diffraction to investigate the structural phase transitions of Fe1+yTe in the vicinity of a tricitical point in the phase diagram. A detailed analysis of the powder diffraction patterns and temperature dependence of the peak widths in Fe1+yTe showed that two-step structural and magnetic phase transitions occur within the compositional range 0.11≤y≤0.13. The phase transitions are sluggish, indicating a strong competition between the orthorhombic and the monoclinic phases. We combine high-resolution diffraction experiments with specific heat, resistivity, and magnetization measurements and present a revised temperature-composition phase diagram for Fe1+yTe.

  6. Diversity of DIS, SD and psi hairpins in HIV-1 isolates of group M: in silico study.

    PubMed

    Zarudnaya, M I; Potyahaylo, A L; Kolomiets, I N; Hovorun, D M

    2007-01-01

    The primary sequence and secondary structure of the region encompassing DIS, SD and psi hairpins in HIV-1 genomic RNAs have been analyzed for 731 group M isolates from NCBI database. The secondary structures have been predicted by the m fold program (M. Zuker). Though the primary sequence of the region studied was found to be highly heterogeneous, this region is folded into DIS, SD and psi hairpins (DIS-, SD- and psi-like hairpins) in 96% of the isolates studied. The phylogenetic analysis showed that the most frequent variants of DIS hairpin (DIS(Lai), DIS(Mal) and DIS(C)) tolerate certain base changes. Particularly, base changes at stem position 23 occur 5 and 33 times more frequently in DIS(Lai) than in DIS(Mal) and DIS(C), respectively, while A insertion at the 5'end of apical loop is tolerated in DIS(Mal) and DIS(C) but not in DIS(Lai). We have revealed that the bottom base pair substitution G-C --> A-U in SD hairpin is highly specific for subtype D isolates. All variants of DIS, SD and psi hairpins found in our database are discussed, systematized and presented in schemes of hypothetical transitions between variants via a single base change. Most variants of DIS and psi hairpins were found to adopt several conformations. PMID:18030736

  7. Behavior of LiFe1-yMnyPO4/C cathode materials upon electrochemical lithium intercalation/deintercalation

    NASA Astrophysics Data System (ADS)

    Novikova, Svetlana; Yaroslavtsev, Sergey; Rusakov, Vyacheslav; Chekannikov, Andrey; Kulova, Tatiana; Skundin, Alexander; Yaroslavtsev, Andrey

    2015-12-01

    LiFe1-yMnyPO4/C (y = 0-0.3) nanocomposites are prepared by the sol-gel method, and their properties are characterized with the use of the XRD analysis, SEM, impedance spectroscopy, charge/discharge tests, and Mössbauer spectroscopy. The samples with a low manganese content, LiFe1-yMnyPO4 (y = 0.1, 0.2) are characterized by an increased conductivity. In LiFe1-yMnyPO4 (x = 0.1-0.3), electrochemical lithium deintercalation/intercalation proceeds in two stages which due to the subsequent oxidation/reduction of iron and manganese ions. The LiFe1-yMnyPO4/С (y = 0.1, 0.2) samples show enhanced charge/discharge capacity, especially, at high current density (for LiFe0.9Mn0.1PO4/C, the discharge capacity is equal to 142 and 55 mAh g-1 at a current density of 20 and 1600 mA g-1, respectively). Mn2+ ↔ Mn3+ transition in LiFe1-yMnyPO4 proceeds via the solid solutions formation under gradual changes in the potential. For LiFe0.7Mn0.3PO4, oxidation and reduction of iron ions follow the same scenario. According to the Mössbauer spectroscopy data, manganese is orderly distributed in LixFeIII1-yMnyPO4: iron contains not more than one manganese cation in its nearest neighborhood. Moreover, combination of the Mössbauer spectroscopy and X-ray analysis data indicates that, in the interval where solid solutions exist in LixFe0.7Mn0.3PO4, the regions with an inhomogeneous distribution of divalent and trivalent manganese ions are formed.

  8. The estrogenic effects of benzylparaben at low doses based on uterotrophic assay in immature SD rats.

    PubMed

    Hu, Ying; Zhang, Zhaobin; Sun, Libei; Zhu, Desheng; Liu, Qingchun; Jiao, Jian; Li, Jun; Qi, Mingwen

    2013-03-01

    Benzylparaben (BzP), a type of parabens being used as a preservative agent in cosmetics, food, and pharmaceutical products, may be ingested by humans. In this study, we performed an immature uterotrophic assay using Sprague Dawley (SD) rats by intragastric administration to determine the estrogenic effects of BzP and found significant increases in uterine weight with doses of 0.16 mg/kg body weight and higher (P<0.05). The in vivo estrogenicity of BzP was supported by in vitro results from the human estrogen receptor α (hERα)-coactivator recruiting assay and in silico molecular docking analysis performed in this study. The in vitro estrogenic activity of BzP can be observed at concentrations of 1.0×10(-8) M and higher. Molecular docking analysis showed that BzP fits well into the agonist pocket of hERα. The lowest observed effect dose (LOED) (0.16 mg/kg/day) of BzP is much lower than the documented LOEDs of other parabens. Actual risk may exist for people who consume a diet high in BzP or use BzP-laden cosmetics. In addition, we tested the sensitivity of Wistar rats to 17β-estradiol by immature uterotrophic assay, and no obvious uterotrophic response was observed in the rats given doses up to 100 μg/kg body weight. PMID:23220609

  9. Spectrum of {gamma} rays from the decay of SD to normal states in {sup 191}Hg

    SciTech Connect

    Gassmann, D.; Khoo, T.L.; Lauritsen, T.

    1995-08-01

    In B.a.7. we propose that the statistical spectrum emitted from a sharp single excited state serves as a probe of pairing in excited states. A specific test of this proposal is the comparison of the spectra from even-even and odd-even nuclei. Whereas a pair gap exists in an even-even nucleus, it gets filled in an odd-even nucleus. Consequently, low-energy transitions can arise in the latter case, whereas they are calculated to be absent in the former case because very few levels exist in the cold gap region. In addition, transitions between 1.4 - 2.2 MeV, which {open_quotes}jump{close_quotes} across the gap, are predicted to have lower yield in the odd-even nuclei. Serendipitously, decay from a superdeformed state serves as a good initial excited sharp state. We extracted the spectrum pairwise-coincident with SD lines in {sup 191}Hg from Gammasphere data and compared it with the equivalent spectra from the even-even nuclei {sup 192,194}Hg. The differences that are predicted to occur are indeed observed. Thus, the data support our proposal that the reduction of pairing with thermal excitation energy can be probed with statistical decay spectra.

  10. Neutron Skins and Halo Orbits in the sd and pf Shells.

    PubMed

    Bonnard, J; Lenzi, S M; Zuker, A P

    2016-05-27

    The strong dependence of Coulomb energies on nuclear radii makes it possible to extract the latter from calculations of the former. The resulting estimates of neutron skins indicate that two mechanisms are involved. The first one-isovector monopole polarizability-amounts to noting that when a particle is added to a system it drives the radii of neutrons and protons in different directions, tending to equalize the radii of both fluids independently of the neutron excess. This mechanism is well understood and the Duflo-Zuker (small) neutron skin values derived 14 years ago are consistent with recent measures and estimates. The alternative mechanism involves halo orbits whose huge sizes tend to make the neutron skins larger and have a subtle influence on the radial behavior of sd and pf shell nuclei. In particular, they account for the sudden rise in the isotope shifts of nuclei beyond N=28 and the near constancy of radii in the A=40-56 region. This mechanism, detected here for the first time, is not well understood and may well go beyond the Efimov physics usually associated with halo orbits. PMID:27284653

  11. A search for substellar objects orbiting the sdB eclipsing binary HS 0705+6700

    NASA Astrophysics Data System (ADS)

    Qian, S.-B.; Shi, G.; Zola, S.; Koziel-Wierzbowska, D.; Winiarski, M.; Szymanski, T.; Ogloza, W.; Li, L.-J.; Zhu, L.-Y.; Liu, L.; He, J.-J.; Liao, W.-P.; Zhao, E.-G.; Wang, J.-J.; Zhang, J.; Jiang, L.-Q.

    2013-12-01

    By using 78 newly determined timings of light minima together with those collected from the literature, we analysed the changes in the observed minus calculated (O-C) diagram in HS 0705+6700, a short-period (2.3 h) eclipsing binary that consists of a very hot subdwarf B-type (sdB) star and a very cool fully convective red dwarf. We confirmed the cyclic variation in the O-C and refined the parameters of the circumbinary brown dwarf (reported to orbit the binary system in 2009) by analysing the changes for the light travel time effect that arises from the gravitational influence of the third body. Our results indicate the lower mass limit of the third body to be M3 sin i' = 33.7(±1.6) MJup. This companion would be a brown dwarf if its orbital inclination is larger than 27.7° and it is orbiting the central eclipsing binary with an eccentricity e ˜ 0.2 at a separation of about 3.7(±0.1) au.

  12. Classification of SD-OCT Volumes Using Local Binary Patterns: Experimental Validation for DME Detection

    PubMed Central

    Cheung, Carol Y.; Wong, Tien Y.; Lamoureux, Ecosse; Milea, Dan; Mériaudeau, Fabrice; Sidibé, Désiré

    2016-01-01

    This paper addresses the problem of automatic classification of Spectral Domain OCT (SD-OCT) data for automatic identification of patients with DME versus normal subjects. Optical Coherence Tomography (OCT) has been a valuable diagnostic tool for DME, which is among the most common causes of irreversible vision loss in individuals with diabetes. Here, a classification framework with five distinctive steps is proposed and we present an extensive study of each step. Our method considers combination of various preprocessing steps in conjunction with Local Binary Patterns (LBP) features and different mapping strategies. Using linear and nonlinear classifiers, we tested the developed framework on a balanced cohort of 32 patients. Experimental results show that the proposed method outperforms the previous studies by achieving a Sensitivity (SE) and a Specificity (SP) of 81.2% and 93.7%, respectively. Our study concludes that the 3D features and high-level representation of 2D features using patches achieve the best results. However, the effects of preprocessing are inconsistent with different classifiers and feature configurations. PMID:27555965

  13. Effect and mechanism of Salicornia bigelovii Torr. plant salt on blood pressure in SD rats.

    PubMed

    Zhang, Shumeng; Wei, Mingqian; Cao, Chunjie; Ju, Yaoyao; Deng, Yanqun; Ye, Tianwen; Xia, Zufeng; Chen, Meizhen

    2015-03-01

    In this paper, the effect and mechanism of Salicornia bigelovii Torr. plant salt (SPS) on blood pressure in Sprague Dawley (SD) rats were investigated. The results showed that the edible salt induced hypertension, but the SPS did not. Organ indices and Hematoxylin-Eosin (HE) staining analysis indicated that SPS had a protective effect on the kidney and liver. In comparison with the edible salt-treated group, nitric oxide (NO) content, angiotensin-II (Ang-II) and endothelin-1 (ET-1) levels in the serum of the SPS-treated group had no obvious changes, but serum creatinine concentration significantly decreased. Moreover, superoxide dismutase (SOD) and Na(+)-K(+)-ATPase activity increased while malondialdehyde (MDA) content decreased in the SPS-treated group. In conclusion, a long-term high salt intake could lead to hypertension. SPS, as a salt substitute, could increase the body's antioxidant ability to protect the kidney and liver from the damage caused by a high salt intake and effectively avoid the occurrence of hypertension. PMID:25631641

  14. Risk and Vulnerability Analysis of Satellites Due to MM/SD with PIRAT

    NASA Astrophysics Data System (ADS)

    Kempf, Scott; Schafer, Frank Rudolph, Martin; Welty, Nathan; Donath, Therese; Destefanis, Roberto; Grassi, Lilith; Janovsky, Rolf; Evans, Leanne; Winterboer, Arne

    2013-08-01

    Until recently, the state-of-the-art assessment of the threat posed to spacecraft by micrometeoroids and space debris was limited to the application of ballistic limit equations to the outer hull of a spacecraft. The probability of no penetration (PNP) is acceptable for assessing the risk and vulnerability of manned space mission, however, for unmanned missions, whereby penetrations of the spacecraft exterior do not necessarily constitute satellite or mission failure, these values are overly conservative. The newly developed software tool PIRAT (Particle Impact Risk and Vulnerability Analysis Tool) has been developed based on the Schäfer-Ryan-Lambert (SRL) triple-wall ballistic limit equation (BLE), applicable for various satellite components. As a result, it has become possible to assess the individual failure rates of satellite components. This paper demonstrates the modeling of an example satellite, the performance of a PIRAT analysis and the potential for subsequent design optimizations with respect of micrometeoroid and space debris (MM/SD) impact risk.

  15. Immunologic effects of anti-D (WinRho-SD) in children with immune thrombocytopenic purpura.

    PubMed

    Zimmerman, S A; Malinoski, F J; Ware, R E

    1998-02-01

    Intravenous immunoglobulin (IVIG) is an effective treatment for immune thrombocytopenic purpura (ITP) that induces transient blockade of the reticuloendothelial system (RES) with additional effects including alteration of T lymphocyte subsets and suppression of in vitro T lymphocyte proliferation. As anti-D also is an effective treatment for ITP, we investigated its in vitro and in vivo immunologic effects. The in vitro effects of various agents used in ITP therapy were compared using T lymphocyte proliferation assays. Anti-D caused significantly less inhibition than IVIG or dexamethasone, but non-specific protein was as suppressive as IVIG. Six children with chronic ITP were studied following anti-D administration. Patients received a single dose of anti-D (WinRho-SD, 50 microg/kg i.v. over 5 min) and were studied on day 0, day 7, and 1 month later. Anti-D did not affect T lymphocyte subsets including the T cell receptor variable beta repertoire, in vitro T lymphocyte proliferation to mitogens, recall antigens, or interleukin-2, in vitro IgG synthesis induced by pokeweed mitogen, or T lymphocyte cytokine mRNA levels. We conclude that anti-D has no demonstrable in vitro or in vivo effects on lymphocyte enumeration or function, and therefore likely is effective in the treatment of ITP primarily through RES blockade. PMID:9462545

  16. Optimization of a bioactive exopolysaccharide production from endophytic Fusarium solani SD5.

    PubMed

    Mahapatra, Subhadip; Banerjee, Debdulal

    2013-09-12

    Endophytic fungi were less investigated for exopolysaccharide production. In this study endophytic Fusarium solani SD5 was used for optimization of exopolysaccharide production. One variable at a time method and response surface methodology were employed to explore the optimum medium compositions and fermentation conditions. The organism produced maximum exopolysaccharide after 13.68 days of incubation at 28 °C in potato dextrose broth supplemented with (g%/l) glucose, 9.8; yeast extract, 0.69; KCl, 0.05; KH₂PO₄, 0.05 with medium pH 6.46. Use of 50 ml medium in 250 ml Erlenmeyer flask gives highest exopolysaccharide production. The organism produced more than two times higher exopolysaccharide (2.276 ± 0.032 g/l EPS) at optimized condition compared to pre-optimized condition (0.96 ± 0.021). In vivo toxicity test established nontoxic nature of the EPS (≤400 mg EPS/Kg of body weight). The EPS slightly altered intestinal indigenous bacteria and influenced the growth of beneficial Lactobacillus spp. PMID:23911494

  17. Alpha-cluster spectroscopy in 40Ca and in the sd-shell closure region

    NASA Astrophysics Data System (ADS)

    Reidemeister, G.; Ohkubo, S.; Michel, F.

    1990-01-01

    The low-energy 36(α,α) elastic scattering data of Gaul et al. are analyzed within the frame of the optical model, using energy-independent Woods-Saxon squared or model-independent geometries for the real part of the potential. The optical-model scattering amplitude is decomposed into its barrier and internal wave components to understand the rapid and complicated evolution of the angular distributions with incident energy. The properties of the low-energy bound and quasibound states supported by this potential are compared with those of the states of the deformed 4p-4h rotational band in 40Ca, built on the Jπ=0+, Ex=3.35 MeV state. The possibility of extending this local potential model approach to neighboring nuclei near the sd-shell closure is discussed. A negative-parity band of states with appreciable α-cluster character, starting around the α-particle threshold, is expected to be systematically present in this mass region.

  18. Alleviating anastrozole induced bone toxicity by selenium nanoparticles in SD rats.

    PubMed

    Vekariya, Kiritkumar K; Kaur, Jasmine; Tikoo, Kulbhushan

    2013-04-15

    Aromatase inhibitors like anastrozole play an undisputed key role in the treatment of breast cancer, but on the other hand, various side effects like osteoporosis and increased risk of bone fracture accompany the chronic administration of these drugs. Here we show for the first time that selenium nanoparticles, when given in conjugation to anastrozole, lower the bone toxicity caused by anastrozole and thus reduce the probable damage to the bone. Selenium nanoparticles at a dose of 5μg/ml significantly reduced the cell death caused by anastrozole (1μM) in HOS (human osteoblast) cells. In addition, our results also highlighted that in female SD rat model, SeNPs (0.25, 0.5, 1mg/kg/day) significantly prevented the decrease in bone density and increase in biochemical markers of bone resorption induced by anastrozole (0.2mg/kg/day) treatment. Histopathological examination of the femurs of SeNP treated group revealed ossification, mineralization, calcified cartilaginous deposits and a marginal osteoclastic activity, all of which indicate a marked restorative action, suggesting the protective action of the SeNPs. Interestingly, SeNPs (1mg/kg/day) also exhibited protective effect in ovariectomized rat model, by preventing osteoporosis, which signifies that bone loss due to estrogen deficiency can be effectively overcome by using SeNPs. PMID:23415680

  19. Classification of SD-OCT Volumes Using Local Binary Patterns: Experimental Validation for DME Detection.

    PubMed

    Lemaître, Guillaume; Rastgoo, Mojdeh; Massich, Joan; Cheung, Carol Y; Wong, Tien Y; Lamoureux, Ecosse; Milea, Dan; Mériaudeau, Fabrice; Sidibé, Désiré

    2016-01-01

    This paper addresses the problem of automatic classification of Spectral Domain OCT (SD-OCT) data for automatic identification of patients with DME versus normal subjects. Optical Coherence Tomography (OCT) has been a valuable diagnostic tool for DME, which is among the most common causes of irreversible vision loss in individuals with diabetes. Here, a classification framework with five distinctive steps is proposed and we present an extensive study of each step. Our method considers combination of various preprocessing steps in conjunction with Local Binary Patterns (LBP) features and different mapping strategies. Using linear and nonlinear classifiers, we tested the developed framework on a balanced cohort of 32 patients. Experimental results show that the proposed method outperforms the previous studies by achieving a Sensitivity (SE) and a Specificity (SP) of 81.2% and 93.7%, respectively. Our study concludes that the 3D features and high-level representation of 2D features using patches achieve the best results. However, the effects of preprocessing are inconsistent with different classifiers and feature configurations. PMID:27555965

  20. The crystal structure of the superconducting copper oxide carbonate (Ba 1- xSr x) 2Cu 1+ yO 2+2 y+ z(CO 3) 1- y. Defects in charge reservoirs and superconductivity

    NASA Astrophysics Data System (ADS)

    Izumi, Fujio; Kinoshita, Kyoichi; Matsui, Yoshio; Yanagisawa, Kasumi; Ishigaki, Tōru; Kamiyama, Takashi; Yamada, Tomoaki; Asano, Hajime

    1992-06-01

    The crystal structure of a new superconductor in the Ba-Sr-Cu-C-O system has been determined by neutron powder diffraction with the auxiliary use of electron diffraction and high-resolution transmission electron microscopy. This compound is a member of a solid solution with the general formula (Ba 1- xSr x) 2Cu 1+ yO 2+2 y+ zCO 3) 1- y, where x=4/9 , y=1/9, and z=0.10. It is tetragonal with a space group P42 12 or P overline42 1m and lattice parameters of a=5.56405 (18) Å and c=7.8570(4) Å. It is closely related in structure to Sr 2CuO 2CO 3, which is an end member of the solid solution: x=1, y=0, and x=0. Two-dimensional CuO 2 sheets and carbonate slabs, (Ba 1- xSr s) 2Cu yO 2 y+ z(CO 3) 1- y, alternate with each other along the [001] directions. As the formula of the slab shows, about 11% of C atoms are substituted by excess Cu atoms coordinated to O atoms which amount to 2 y+ z in the formula unit. These substitutional and interstitial defects enable hole carriers to move from the carbonate slab to the CuO 2 conduction sheet.

  1. Discovery, characterization and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa

    PubMed Central

    McCaughey, Laura C.; Josts, Inokentijs; Grinter, Rhys; White, Paul; Byron, Olwyn; Tucker, Nicholas P.; Matthews, Jacqueline M.; Kleanthous, Colin; Whitchurch, Cynthia B.; Walker, Daniel

    2016-01-01

    Increasing rates of antibiotic resistance among Gram-negative pathogens such as Pseudomonas aeruginosa means alternative approaches to antibiotic development are urgently required. Pyocins, produced by P. aeruginosa for intraspecies competition, are highly potent protein antibiotics known to actively translocate across the outer membrane of P. aeruginosa. Understanding and exploiting the mechanisms by which pyocins target, penetrate and kill P. aeruginosa is a promising approach to antibiotic development. In this work we show the therapeutic potential of a newly identified tRNase pyocin, pyocin SD2, by demonstrating its activity in vivo in a murine model of P. aeruginosa lung infection. In addition, we propose a mechanism of cell targeting and translocation for pyocin SD2 across the P. aeruginosa outer membrane. Pyocin SD2 is concentrated at the cell surface, via binding to the common polysaccharide antigen (CPA) of P. aeruginosa lipopolysaccharide (LPS), from where it can efficiently locate its outer membrane receptor FpvAI. This strategy of utilizing both the CPA and a protein receptor for cell targeting is common among pyocins as we show that pyocins S2, S5 and SD3 also bind to the CPA. Additional data indicate a key role for an unstructured N-terminal region of pyocin SD2 in the subsequent translocation of the pyocin into the cell. These results greatly improve our understanding of how pyocins target and translocate across the outer membrane of P. aeruginosa. This knowledge could be useful for the development of novel anti-pseudomonal therapeutics and will also support the development of pyocin SD2 as a therapeutic in its own right. PMID:27252387

  2. Discovery, characterization and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa.

    PubMed

    McCaughey, Laura C; Josts, Inokentijs; Grinter, Rhys; White, Paul; Byron, Olwyn; Tucker, Nicholas P; Matthews, Jacqueline M; Kleanthous, Colin; Whitchurch, Cynthia B; Walker, Daniel

    2016-08-01

    Increasing rates of antibiotic resistance among Gram-negative pathogens such as Pseudomonas aeruginosa means alternative approaches to antibiotic development are urgently required. Pyocins, produced by P. aeruginosa for intraspecies competition, are highly potent protein antibiotics known to actively translocate across the outer membrane of P. aeruginosa. Understanding and exploiting the mechanisms by which pyocins target, penetrate and kill P. aeruginosa is a promising approach to antibiotic development. In this work we show the therapeutic potential of a newly identified tRNase pyocin, pyocin SD2, by demonstrating its activity in vivo in a murine model of P. aeruginosa lung infection. In addition, we propose a mechanism of cell targeting and translocation for pyocin SD2 across the P. aeruginosa outer membrane. Pyocin SD2 is concentrated at the cell surface, via binding to the common polysaccharide antigen (CPA) of P. aeruginosa lipopolysaccharide (LPS), from where it can efficiently locate its outer membrane receptor FpvAI. This strategy of utilizing both the CPA and a protein receptor for cell targeting is common among pyocins as we show that pyocins S2, S5 and SD3 also bind to the CPA. Additional data indicate a key role for an unstructured N-terminal region of pyocin SD2 in the subsequent translocation of the pyocin into the cell. These results greatly improve our understanding of how pyocins target and translocate across the outer membrane of P. aeruginosa. This knowledge could be useful for the development of novel anti-pseudomonal therapeutics and will also support the development of pyocin SD2 as a therapeutic in its own right. PMID:27252387

  3. Chemical analyses of pore water from boreholes USW SD-6 and USW WT-24, Yucca Mountain, Nevada.

    PubMed

    Yang, In C; Peterman, Zell E; Scofield, Kevin M

    2003-01-01

    Analyses of pore water extracted from cores of boreholes USW SD-6 in the central part and USW WT-24 in the northern part of Yucca Mountain, Nevada, show significant vertical and lateral variations in dissolved-ion concentrations. Analyses of samples of only a few milliliters of pore water extracted by uniaxial or triaxial compression and by ultracentrifugation methods from adjacent core samples are generally in agreement, within the analytical error of 10% to 15%. However, the values of silica for water obtained by ultracentrifugation are consistently lower than values for water obtained by compression. The larger concentrations probably are due to localized pressure solution of silicate minerals during compression. The shallower water from core in borehole USW SD-6 was extracted from nonwelded units collectively referred to as the Paintbrush Tuff nonwelded (PTn). The deeper water was from core in both boreholes USW SD-6 and USW WT-24 in the nonwelded units referred to as the Calico Hills nonwelded (CHn). Significant differences in mean dissolved-ion concentrations in pore water between the PTn and CHn are (1) decreases in Ca, Mg, SO(4), and NO(3) and (2) increases in HCO(3) and (Na+K)/(Ca+Mg) ratios. The decrease in NO(3) and the increase in HCO(3) could be the result of denitrification through the oxidation of organic matter. The decrease in Ca and associated increase in (Na+K)/(Ca+Mg) is the result of ion exchange with zeolites in the CHn in borehole USW WT-24. This effect is not nearly as pronounced in borehole USW SD-6, probably reflecting a smaller amount of zeolitization of the CHn in USW SD-6. Geochemical calculations using the PHREEQC code indicate that the pore water from both boreholes USW SD-6 and USW WT-24 is uniformly undersaturated in anhydrite, gypsum, and amorphous silica, but supersaturated in quartz and chalcedony. The saturation of calcite, aragonite, sepiolite, and dolomite is more variable from sample to sample. PMID:12714300

  4. Aquaporin 4-specific T cells and NMO-IgG cause primary retinal damage in experimental NMO/SD.

    PubMed

    Zeka, Bleranda; Hastermann, Maria; Kaufmann, Nathalie; Schanda, Kathrin; Pende, Marko; Misu, Tatsuro; Rommer, Paulus; Fujihara, Kazuo; Nakashima, Ichiro; Dahle, Charlotte; Leutmezer, Fritz; Reindl, Markus; Lassmann, Hans; Bradl, Monika

    2016-01-01

    Neuromyelitis optica/spectrum disorder (NMO/SD) is a severe, inflammatory disease of the central nervous system (CNS). In the majority of patients, it is associated with the presence of pathogenic serum autoantibodies (the so-called NMO-IgGs) directed against the water channel aquaporin 4 (AQP4), and with the formation of large, astrocyte-destructive lesions in spinal cord and optic nerves. A large number of recent studies using optical coherence tomography (OCT) demonstrated that damage to optic nerves in NMO/SD is also associated with retinal injury, as evidenced by retinal nerve fiber layer (RNFL) thinning and microcystic inner nuclear layer abnormalities. These studies concluded that retinal injury in NMO/SD patients results from secondary neurodegeneration triggered by optic neuritis.However, the eye also contains cells expressing AQP4, i.e., Müller cells and astrocytes in the retina, epithelial cells of the ciliary body, and epithelial cells of the iris, which raised the question whether the eye can also be a primary target in NMO/SD. Here, we addressed this point in experimental NMO/SD (ENMO) induced in Lewis rat by transfer of AQP4268-285-specific T cells and NMO-IgG.We show that these animals show retinitis and subsequent dysfunction/damage of retinal axons and neurons, and that this pathology occurs independently of the action of NMO-IgG. We further show that in the retinae of ENMO animals Müller cell side branches lose AQP4 reactivity, while retinal astrocytes and Müller cell processes in the RNFL/ganglionic cell layers are spared. These changes only occur in the presence of both AQP4268-285-specific T cells and NMO-IgG.Cumulatively, our data show that damage to retinal cells can be a primary event in NMO/SD. PMID:27503347

  5. Primordial SdS universe from a 5D vacuum: scalar field fluctuations on Schwarzschild and Hubble horizons

    SciTech Connect

    Aguilar, José Edgar Madriz; Bellini, Mauricio E-mail: mbellini@mdp.edu.ar

    2010-11-01

    We study scalar field fluctuations of the inflaton field in an early inflationary universe on an effective 4D Schwarzschild-de Sitter (SdS) metric, which is obtained after make a planar coordinate transformation on a 5D Ricci-flat Schwarzschild-de Sitter (SdS) static metric. We obtain the important result that the spectrum of fluctuations at zeroth order is independent of the scalar field mass M on Schwarzschild scales, while on cosmological scales it exhibits a mass dependence. However, in the first-order expansion, the spectrum depends of the inflaton mass and the amplitude is linear with the Black-Hole (BH) mass m.

  6. A magnetic glassy phase in Fe1+ySexTe1-x single crystals

    NASA Astrophysics Data System (ADS)

    Lamura, G.; Shiroka, T.; Bonfà, P.; Sanna, S.; Bernardini, F.; De Renzi, R.; Viennois, R.; Giannini, E.; Piriou, A.; Emery, N.; Cimberle, M. R.; Putti, M.

    2013-04-01

    The evolution of magnetic order in Fe1+ySexTe1-x crystals as a function of Se content was investigated by means of ac/dc magnetometry and muon-spin spectroscopy. Experimental results and self-consistent density functional theory calculations both indicate that muons are implanted in vacant iron-excess sites, where they probe a local field mainly of dipolar origin, resulting from an antiferromagnetic (AFM) bicollinear arrangement of iron spins. This long-range AFM phase becomes progressively disordered with increasing Se content. At the same time all the tested samples manifest a marked glassy character that vanishes for high Se contents. The presence of local electronic/compositional inhomogeneities most likely favours the growth of clusters whose magnetic moment ‘freezes’ at low temperature. This glassy magnetic phase justifies both the coherent muon precession seen at short times in the asymmetry data, as well as the glassy behaviour evidenced by both dc and ac magnetometry.

  7. Impact ionization in AlxGa1-xAsySb1-y avalanche photodiodes

    NASA Astrophysics Data System (ADS)

    Grzesik, M.; Donnelly, J.; Duerr, E.; Manfra, M.; Diagne, M.; Bailey, R.; Turner, G.; Goodhue, W.

    2014-04-01

    Avalanche photodiodes (APDs) have been fabricated in order to determine the impact ionization coefficients of electrons (α) and holes (β) in AlxGa1-xAsySb1-y lattice matched to GaSb for three alloy compositions: (x = 0.40, y = 0.035), (x = 0.55, y = 0.045), and (x = 0. 65, y = 0.054). The impact ionization coefficients were calculated from photomultiplication measurements made on specially designed APDs, which allowed for both pure electron and pure hole injection in the same device. Photo-multiplication measurements were made at temperatures ranging from 77 K to 300 K for all three alloys. A quasi-physical model with an explicit temperature dependence was used to express the impact ionization coefficients as a function of electric-field strength and temperature. For all three alloys, it was found that α < β at any given temperature. In addition, the values of the impact ionization coefficients were found to decrease as the aluminum concentration of the AlGaAsSb alloy was increased. A value between 1.2 and 4.0 was found for β/α, which is dependent on temperature, alloy composition, and electric-field strength.

  8. Thermal Stability of MgyTi1-y Thin Films Investigated by Positron Annihilation Spectroscopy

    NASA Astrophysics Data System (ADS)

    Anastasopol, A.; Eijt, S. W. H.; Schut, H.; Mulder, F. M.; Plazaola, F.; Dam, B.

    Mg-Ti compounds are attractive candidates as hydrogen storage materials for their fast sorption kinetics and high storage capacity. In this context, an investigation of their thermal stability is of great importance. The thermal stability of MgyTi1-y thin films was investigated using positron annihilation spectroscopy. Despite the positive enthalpy of mixing of Mg and Ti, positron Doppler Broadening of Annihilation Radiation (DBAR) depth profiling showed that Mg0.9Ti0.1 films are stable up to 300°C. However, for Mg0.7Ti0.3 films, segregation of Mg and Ti was observed at 300oC by the appearance of a clear Ti signature in the S-W diagrams and in the Doppler broadening depth profiles analyzed using VEPFIT. The thickness of the 250-300 nm thin films remained unchanged during the heating treatments. We further present ab-initio calculations of positron lifetimes of the corresponding metal and metal hydride phases for comparison to our previous positron annihilation lifetime spectroscopy (PALS) study.

  9. Alleviating anastrozole induced bone toxicity by selenium nanoparticles in SD rats

    SciTech Connect

    Vekariya, Kiritkumar K.; Kaur, Jasmine; Tikoo, Kulbhushan

    2013-04-15

    Aromatase inhibitors like anastrozole play an undisputed key role in the treatment of breast cancer, but on the other hand, various side effects like osteoporosis and increased risk of bone fracture accompany the chronic administration of these drugs. Here we show for the first time that selenium nanoparticles, when given in conjugation to anastrozole, lower the bone toxicity caused by anastrozole and thus reduce the probable damage to the bone. Selenium nanoparticles at a dose of 5 μg/ml significantly reduced the cell death caused by anastrozole (1 μM) in HOS (human osteoblast) cells. In addition, our results also highlighted that in female SD rat model, SeNPs (0.25, 0.5, 1 mg/kg/day) significantly prevented the decrease in bone density and increase in biochemical markers of bone resorption induced by anastrozole (0.2 mg/kg/day) treatment. Histopathological examination of the femurs of SeNP treated group revealed ossification, mineralization, calcified cartilaginous deposits and a marginal osteoclastic activity, all of which indicate a marked restorative action, suggesting the protective action of the SeNPs. Interestingly, SeNPs (1 mg/kg/day) also exhibited protective effect in ovariectomized rat model, by preventing osteoporosis, which signifies that bone loss due to estrogen deficiency can be effectively overcome by using SeNPs. - Highlights: ► SeNPs significantly reduce bone toxicity in anastrozole treated rats. ► SeNPs successfully prevented osteoporosis in ovariectomized rats. ► SeNP treatment lowered the levels of TRAP and increased the levels of ALKP.

  10. Improved Determination of the Atmospheric Parameters of the Pulsating sdB Star Feige 48

    NASA Astrophysics Data System (ADS)

    Latour, M.; Fontaine, G.; Green, E. M.; Brassard, P.; Chayer, P.

    2014-06-01

    As part of a multifaceted effort to better exploit the asteroseismological potential of the pulsating sdB star Feige 48, we present an improved spectroscopic analysis of that star based on new grids of NLTE, fully line-blanketed model atmospheres. To that end, we gathered four high signal-to-noise ratio time-averaged optical spectra of varying spectral resolutions from 1.0 Å to 8.7 Å, and we made use of the results of four independent studies to fix the abundances of the most important metals in the atmosphere of Feige 48. The mean atmospheric parameters we obtained from our four spectra of Feige 48 are: T eff = 29,850 ± 60 K, log g = 5.46 ± 0.01, and log N(He)/N(H) = -2.88 ± 0.02. We also modeled, for the first time, the He II line at 1640 Å from the STIS archive spectrum of the star, and with this line we found an effective temperature and a surface gravity that match well with the values obtained with the optical data. With some fine tuning of the abundances of the metals visible in the optical domain, we were able to achieve a very good agreement between our best available spectrum and our best-fitting synthetic one. Our derived atmospheric parameters for Feige 48 are in rather good agreement with previous estimates based on less sophisticated models. This underlines the relatively small effects of the NLTE approach combined with line blanketing in the atmosphere of this particular star, implying that the current estimates of the atmospheric parameters of Feige 48 are reliable and secure.

  11. Improved determination of the atmospheric parameters of the pulsating sdB star Feige 48

    SciTech Connect

    Latour, M.; Fontaine, G.; Brassard, P.; Green, E. M.; Chayer, P.

    2014-06-10

    As part of a multifaceted effort to better exploit the asteroseismological potential of the pulsating sdB star Feige 48, we present an improved spectroscopic analysis of that star based on new grids of NLTE, fully line-blanketed model atmospheres. To that end, we gathered four high signal-to-noise ratio time-averaged optical spectra of varying spectral resolutions from 1.0 Å to 8.7 Å, and we made use of the results of four independent studies to fix the abundances of the most important metals in the atmosphere of Feige 48. The mean atmospheric parameters we obtained from our four spectra of Feige 48 are: T {sub eff} = 29,850 ± 60 K, log g = 5.46 ± 0.01, and log N(He)/N(H) = –2.88 ± 0.02. We also modeled, for the first time, the He II line at 1640 Å from the STIS archive spectrum of the star, and with this line we found an effective temperature and a surface gravity that match well with the values obtained with the optical data. With some fine tuning of the abundances of the metals visible in the optical domain, we were able to achieve a very good agreement between our best available spectrum and our best-fitting synthetic one. Our derived atmospheric parameters for Feige 48 are in rather good agreement with previous estimates based on less sophisticated models. This underlines the relatively small effects of the NLTE approach combined with line blanketing in the atmosphere of this particular star, implying that the current estimates of the atmospheric parameters of Feige 48 are reliable and secure.

  12. Heterologous Expression and Characterization of the Manganese-Oxidizing Protein from Erythrobacter sp. Strain SD21

    PubMed Central

    Nakama, Katherine; Medina, Michael; Lien, Ahn; Ruggieri, Jordan; Collins, Krystle

    2014-01-01

    The manganese (Mn)-oxidizing protein (MopA) from Erythrobacter sp. strain SD21 is part of a unique enzymatic family that is capable of oxidizing soluble Mn(II). This enzyme contains two domains, an animal heme peroxidase domain, which contains the catalytic site, followed by a C-terminal calcium binding domain. Different from the bacterial Mn-oxidizing multicopper oxidase enzymes, little is known about MopA. To gain a better understanding of MopA and its role in Mn(II) oxidation, the 238-kDa full-length protein and a 105-kDa truncated protein containing only the animal heme peroxidase domain were cloned and heterologously expressed in Escherichia coli. Despite having sequence similarity to a peroxidase, hydrogen peroxide did not stimulate activity, nor was activity significantly decreased in the presence of catalase. Both pyrroloquinoline quinone (PQQ) and hemin increased Mn-oxidizing activity, and calcium was required. The Km for Mn(II) of the full-length protein in cell extract was similar to that of the natively expressed protein, but the Km value for the truncated protein in cell extract was approximately 6-fold higher than that of the full-length protein, suggesting that the calcium binding domain may aid in binding Mn(II). Characterization of the heterologously expressed MopA has provided additional insight into the mechanism of bacterial Mn(II) oxidation, which will aid in understanding the role of MopA and Mn oxidation in bioremediation and biogeochemical cycling. PMID:25172859

  13. Purification and Characterization of the Manganese(II) Oxidizing Protein from Erythrobacter sp. SD-21

    NASA Astrophysics Data System (ADS)

    Nakama, K. R.; Lien, A.; Johnson, H. A.

    2013-12-01

    The manganese(II) oxidizing protein (Mop) found in the alpha-proteobacterium Erythrobacter sp. SD-21 catalyzes the formation of insoluble Mn(III/IV) oxides from soluble Mn(II). These Mn(III/IV) oxides formed are one of the strongest naturally occurring oxides, next to oxygen, and can be used to adsorb and oxidize toxic chemicals from the surrounding environment. Because of the beneficial use in the treatment of contaminated sources, the mechanism and biochemical properties of this novel enzyme are being studied. Due to low expression levels in the native host strain, purification of Mop has been problematic. To overcome this problem the gene encoding Mop, mopA, was cloned from the native host into a C-terminal histidine tag vector and expressed in Escherichia coli cells. Affinity chromatography under denaturing conditions have been applied in attempts to purify an active Mop. Western blots have confirmed that the protein is being expressed and is at the expected size of 250 kDa. Preliminary characterization on crude extract containing Mop has shown a Km and vmax value of 2453 uM and 0.025 uM min-1, respectively. Heme and pyrroloquinoline quinone can stimulate Mn(II) oxidizing activity, but hydrogen peroxide does not affect activity, despite the sequence similarity to animal heme peroxidase proteins. Research has been shown that calcium is essential for Mop activity. Purifying an active Mn(II) oxidizing protein will allow for a better understanding behind the enigmatic process of Mn(II) oxidation.

  14. Heterologous expression and characterization of the manganese-oxidizing protein from Erythrobacter sp. strain SD21.

    PubMed

    Nakama, Katherine; Medina, Michael; Lien, Ahn; Ruggieri, Jordan; Collins, Krystle; Johnson, Hope A

    2014-11-01

    The manganese (Mn)-oxidizing protein (MopA) from Erythrobacter sp. strain SD21 is part of a unique enzymatic family that is capable of oxidizing soluble Mn(II). This enzyme contains two domains, an animal heme peroxidase domain, which contains the catalytic site, followed by a C-terminal calcium binding domain. Different from the bacterial Mn-oxidizing multicopper oxidase enzymes, little is known about MopA. To gain a better understanding of MopA and its role in Mn(II) oxidation, the 238-kDa full-length protein and a 105-kDa truncated protein containing only the animal heme peroxidase domain were cloned and heterologously expressed in Escherichia coli. Despite having sequence similarity to a peroxidase, hydrogen peroxide did not stimulate activity, nor was activity significantly decreased in the presence of catalase. Both pyrroloquinoline quinone (PQQ) and hemin increased Mn-oxidizing activity, and calcium was required. The Km for Mn(II) of the full-length protein in cell extract was similar to that of the natively expressed protein, but the Km value for the truncated protein in cell extract was approximately 6-fold higher than that of the full-length protein, suggesting that the calcium binding domain may aid in binding Mn(II). Characterization of the heterologously expressed MopA has provided additional insight into the mechanism of bacterial Mn(II) oxidation, which will aid in understanding the role of MopA and Mn oxidation in bioremediation and biogeochemical cycling. PMID:25172859

  15. Wurtzite Zn1-y(MgxCd1-x)yO quaternary systems for photodiodes in visible spectral range

    NASA Astrophysics Data System (ADS)

    Nieda, Yoshiaki; Suzuki, Mari; Nakamura, Atsushi; Temmyo, Jiro; Tabares, Gema; Kurtz, Alejandro; Lopez, Manuel; Ulloa, José María; Hierro, Adrian; Muñoz, Elías

    2016-09-01

    We investigated the optical bandgap engineering of ZnO based quaternary alloy films of wurtzite Zn1-y(MgxCd1-x)yO for photodiodes in visible spectral range. Quaternary alloy films were successfully synthesized by remote-plasma enhanced metalorganic chemical vapor deposition (RPE-MOCVD). The wurtzite alloy system has an optical bandgap energy between 2.16 eV and 3.25 eV, which was controlled by the flow ratio of metalorganic sources. The crystal structure and composition was analyzed by X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). This revealed that carrier compensation effects by alloying with MgO in Zn1-xCdxO system decreases carrier concentration. Strong compensation effects were observed in the bandgap range of Zn1-y(MgxCd1-x)yO between 3.0 eV to 3.25 eV and the carrier concentration decreased to 1015-1018 cm-3. Schottky diodes of PEDOT: PSS/Zn1-y(MgxCd1-y)yO with optical bandgaps in the visible spectral range were fabricated to confirm the viability of photovoltaic applications. The diodes performed photovoltaic characteristics under a Xe-Hg lamp illumination through Schottky junctions. The photoresponse spectra showed a photosensitivity with cutoff energy of 2.23 eV and peak energy of 2.90 eV at 0 V biasing.

  16. Normal pressure synthesis of (Tl1-yCy)Ba2Ca3Cu4O12-δ superconductor

    NASA Astrophysics Data System (ADS)

    Khan, Nawazish A.; Ahmad, Shakeel; Khurram, A. A.; Ahmad, Maqsood

    2012-10-01

    Single phase (Tl1-yCy)Ba2Ca3Cu4O12-δ (Tl1-yCy-1234) (y = 0, 0.25, 0.5 and 0.75) superconductor samples have been prepared by solid state reaction method. The FTIR absorption measurements have confirmed the substitution of carbon at thallium site in the charge reservoir layer, (Tl1-yCy)Ba2O4-δ. The electron micrographs of these samples have shown that the carbon substitution has improved the grain morphology of Tl0.75C0.25-1234 sample. The y = 0.25 was found to be the optimum carbon concentration to achieve higher superconducting transition temperature Tc[0] and improved grain morphology. The superconducting transition temperature of Tl0.75C0.25-1234 sample has been increased to 100 K whereas a decrease in the superconducting transition temperature of Tl1-yCy-1234 (y = 0.5 and 0.75) samples was observed. However, the magnitude of diamagnetism has been decreased in all the carbon substituted samples.

  17. 40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL...

  18. Identification of a New Marine Bacterial Strain SD8 and Optimization of Its Culture Conditions for Producing Alkaline Protease

    PubMed Central

    Cui, Hongxia; Yang, Muyang; Wang, Liping; Xian, Cory J.

    2015-01-01

    While much attention has been given to marine microorganisms for production of enzymes, which in general are relatively more stable and active compared to those from plants and animals, studies on alkaline protease production from marine microorganisms have been very limited. In the present study, the alkaline protease producing marine bacterial strain SD8 isolated from sea muds in the Geziwo Qinhuangdao sea area of China was characterized and its optimal culture conditions were investigated. Strain SD8 was initially classified to belong to genus Pseudomonas by morphological, physiological and biochemical characterizations, and then through 16S rDNA sequence it was identified to be likely Pseudomonas hibiscicola. In addition, the culture mediums, carbon sources and culture conditions of strain SD8 were optimized for maximum production of alkaline protease. Optimum enzyme production (236U/mL when cultured bacteria being at 0.75 mg dry weight/mL fermentation broth) was obtained when the isolate at a 3% inoculum size was grown in LB medium at 20 mL medium/100mL Erlenmeyer flask for 48h culture at 30°C with an initial of pH 7.5. This was the first report of strain Pseudomonas hibiscicola secreting alkaline protease, and the data for its optimal cultural conditions for alkaline protease production has laid a foundation for future exploration for the potential use of SD8 strain for alkaline protease production. PMID:26716833

  19. 76 FR 58241 - Designation for the Aberdeen, SD; Decatur, IL; Hastings, NE; Fulton, IL; the State of Missouri...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ..., Federal Register (76 FR 15937), GIPSA requested applications for designation to provide official services... Grain Inspection, Packers and Stockyards Administration Designation for the Aberdeen, SD; Decatur, IL; Hastings, NE; Fulton, IL; the State of Missouri, and the State of South Carolina Areas AGENCY:...

  20. Identification of a New Marine Bacterial Strain SD8 and Optimization of Its Culture Conditions for Producing Alkaline Protease.

    PubMed

    Cui, Hongxia; Yang, Muyang; Wang, Liping; Xian, Cory J

    2015-01-01

    While much attention has been given to marine microorganisms for production of enzymes, which in general are relatively more stable and active compared to those from plants and animals, studies on alkaline protease production from marine microorganisms have been very limited. In the present study, the alkaline protease producing marine bacterial strain SD8 isolated from sea muds in the Geziwo Qinhuangdao sea area of China was characterized and its optimal culture conditions were investigated. Strain SD8 was initially classified to belong to genus Pseudomonas by morphological, physiological and biochemical characterizations, and then through 16S rDNA sequence it was identified to be likely Pseudomonas hibiscicola. In addition, the culture mediums, carbon sources and culture conditions of strain SD8 were optimized for maximum production of alkaline protease. Optimum enzyme production (236U/mL when cultured bacteria being at 0.75 mg dry weight/mL fermentation broth) was obtained when the isolate at a 3% inoculum size was grown in LB medium at 20 mL medium/100mL Erlenmeyer flask for 48h culture at 30°C with an initial of pH 7.5. This was the first report of strain Pseudomonas hibiscicola secreting alkaline protease, and the data for its optimal cultural conditions for alkaline protease production has laid a foundation for future exploration for the potential use of SD8 strain for alkaline protease production. PMID:26716833

  1. Application of chirally-deuterated (S)-D-(6-2H1)glucose to conformational studies

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Deuterated sugars are widely used to elucidate mechanisms of biosynthesis and of chemical reactions, and to confirm assignments of complex NMR or mass spectra. To date, however, there are few reported syntheses for regio and stereospecifically deuterated pyranoses. Chirally-deuterated (S)-D-(6-**2...

  2. Nocardiopsis sp. SD5: a potent feather degrading rare actinobacterium isolated from feather waste in Tamil Nadu, India.

    PubMed

    Saha, Subhasish; Dhanasekaran, D; Shanmugapriya, S; Latha, S

    2013-07-01

    Feather waste, generated in large quantities as a byproduct of commercial poultry processing, is nearly pure keratin protein, and keratin in its native state is not degradable by common proteolytic enzymes. The aim of the study was to find a potent feather degrading actinobacteria from feather waste soil. Out of 91 actinobacterial isolates recorded from feather waste soil in Tiruchirappalli and Nammakkal District, Tamil Nadu, India, isolate SD5 was selected for characterization because it exhibited significant keratinolytic activity. On the basis of the phenotypic, biochemical characterization and 16S rRNA gene-sequencing studies, the isolate was identified as Nocardiopsis sp. SD5. Protease and keratinase activity of Nocardiopsis sp. SD5 were analyzed. The enzyme was more stable over the neutral pH and the temperature of 40 °C. The optimum temperature and pH for both proteolytic and keratinolytic activity was determined at 50 °C and pH 9, respectively. Enzyme inhibitors, detergents and chelator declined the enzyme activity with increasing concentration. Nondenaturing polyacrylamide gel electrophoresis and zymogram elucidated the presence of 30 and 60 kDa protease enzymes. These findings indicated that thermo alkaliphilic feather degrading strain Nocardiopsis sp. SD5 could be used to control the feather waste pollution and to convert keratin rich feather waste into useful feedstock for poultry industry. PMID:23864545

  3. Nocardiopsis sp. SD5: A potent feather degrading rare actinobacterium isolated from feather waste in Tamil Nadu, India.

    PubMed

    Saha, Subhasish; Dhanasekaran, D; Shanmugapriya, S; Latha, S

    2012-08-23

    Feather waste, generated in large quantities as a byproduct of commercial poultry processing, is nearly pure keratin protein, and keratin in its native state is not degradable by common proteolytic enzymes. The aim of the study was to find a potent feather degrading actinobacteria from feather waste soil. Out of 91 actinobacterial isolates recorded from feather waste soil in Tiruchirappalli and Nammakkal District, Tamil Nadu, India, isolate SD5 was selected for characterization because it exhibited significant keratinolytic activity. On the basis of the phenotypic, biochemical characterization and 16S rRNA gene-sequencing studies, the isolate was identified as Nocardiopsis sp. SD5. Protease and keratinase activity of Nocardiopsis sp. SD5 were analyzed. The enzyme was more stable over the neutral pH and the temperature of 40 °C. The optimum temperature and pH for both proteolytic and keratinolytic activity was determined at 50 °C and pH 9, respectively. Enzyme inhibitors, detergents and chelator declined the enzyme activity with increasing concentration. Non denaturing poly acrylamide gel electrophoresis and zymogram elucidated the presence of 30 kda and 60 kda protease enzymes. These findings indicated that thermo alkaliphilic feather degrading strain Nocardiopsis sp. SD5 could be used to control the feather waste pollution and to convert keratin rich feather waste into useful feedstock for poultry industry. (© 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim). PMID:22914902

  4. HS 2333+3927: A new sdB+dM binary with a large reflection effect

    NASA Astrophysics Data System (ADS)

    Heber, U.; Drechsel, H.; Østensen, R.; Karl, C.; Napiwotzki, R.; Altmann, M.; Cordes, O.; Solheim, J.-E.; Voss, B.; Koester, D.; Folkes, S.

    2004-06-01

    We have discovered periodic light variations (P = 0.1718023 d) in the sdB star HS 2333+3927 in the BVR bands with amplitudes of 0.21, 0.28 and 0.33 mag, respectively. Sinusoidal radial velocity variations at the same period were detected with a semi-amplitude of K1 = 89.6 km s-1, indicating that it is binary system and that the light variations are caused by the reflection effect with no eclipses. A mass function of f(m)= 0.0128 M⊙ has been determined. The analysis of the light curve did not yield a unique solution, mainly because the albedo of the secondary is poorly constrained. Two solutions of equal quality with a high (A2= 1.0) and a low (A2= 0.39) albedo were considered further. Variability of the Balmer line profiles, most notably for Hα, was discovered, probably also caused by the reflection effect. A spectroscopic analysis results in Teff = 36 500 K, log g = 5.70, and log (nHe/nH) = -2.15. These characteristics are typical for sdB stars. Mass-radius relations are derived from the results of the analysis of light and radial-velocity curves. Comparison with the observed mass-radius relation of the sdB star and with that of lower main sequence stars for the companion allows us to discard the high albedo solution, because the resulting mass of the primary and the radius of the secondary would be unreasonably low. From a discussion of evolutionary models we constrain the plausible mass of the sdB to the range between 0.29 M⊙ and 0.47 M⊙. Accordingly, the mass of the secondary is between 0.24 M⊙ and 0.32 M⊙, indicating a spectral type of M3 to M4. HS 2333+3927 is only the sixth sdB+dM system discovered so far. An improved measurement of the gravity and the projected rotational velocity of the sdB star is required to further constrain the masses and to identify the evolutionary state of the sdB star uniquely. Based on observations obtained at the German-Spanish Astronomical Center (DSAZ) at Calar Alto, the Nordic Optical Telescope (NOT) and the Jacobus

  5. A CHANDRA OBSERVATION OF THE NEARBY SCULPTOR GROUP Sd GALAXY NGC 7793

    SciTech Connect

    Pannuti, Thomas G.; Staggs, Wayne D.; Schlegel, Eric M.; Filipovic, Miroslav D.; Payne, Jeffrey L.; Petre, Robert

    2011-07-15

    We conducted a Chandra ACIS observation of the nearby Sculptor Group Sd galaxy NGC 7793 as part of a multiwavelength study of supernova remnants (SNRs) in nearby galaxies. At the assumed distance to NGC 7793 of 3.91 Mpc, the limiting unabsorbed luminosity of the detected discrete X-ray sources is L{sub X} (0.2-10.0 keV) {approx}3x10{sup 36} erg s{sup -1}. A total of 22 discrete sources were detected at the {approx}3{sigma} level or greater including one ultraluminous X-ray source (ULX). Based on multiwavelength comparisons, we identify X-ray sources coincident with one SNR, the candidate microquasar N7793-S26, one H II region, and two foreground Galactic stars. We also find that the X-ray counterpart to the candidate radio SNR R3 is time variable in its X-ray emission: we therefore rule out the possibility that this source is a single SNR. A marked asymmetry is seen in the distribution of the discrete sources with the majority lying in the eastern half of this galaxy. All of the sources were analyzed using quantiles to estimate spectral properties and spectra of the four brightest sources (including the ULX) were extracted and analyzed. We searched for time variability in the X-ray emission of the detected discrete sources using our measured fluxes along with fluxes measured from prior Einstein and Roentgensatellit observations. From this study, three discrete X-ray sources are established to be significantly variable. A spectral analysis of the galaxy's diffuse emission is characterized by a temperature of kT = 0.19-0.25 keV. The luminosity function of the discrete sources shows a slope with an absolute value of {Gamma} = -0.65 {+-} 0.11 if we exclude the ULX. If the ULX is included, the luminosity function has a long tail to high L{sub X} with a poor-fitting slope of {Gamma} = -0.62 {+-} 0.2. The ULX-less slope is comparable to the slopes measured for the distributions of NGC 6946 and NGC 2403 but much shallower than the slopes measured for the distributions of

  6. High Brightness Picture Technology In SD-P40 Projection TV

    NASA Astrophysics Data System (ADS)

    Hasegawa, Shinichi

    1987-04-01

    Pioneer Electric Company has developed a new generation 40-inch rear projection SD-P40 television, a revolutionary, new television that realizes white peak brightness of 300 ft-I and high contrast. The combination of high brightness and high contrast is made possible primarily by newly developed optical-coupling technology that utilizes newly developed concepts. This new optical coupling technology cools the CRT quite efficiently, making it possible to greatly increase the CRT power input to obtain high brightness and at the same time provides greater reliability than direct view televisions. The new optical-coupling technology also makes it possible to almost completely eliminate the reflectance at the boundaries between the CRT and the lens and air, which gives much higher contrast than previous televisions. Not only does this optical-coupling technology provide high performance, in addition since the liquid coolant it employs functions as a liquid lens, the coupling lens can be designed to a uniform thinness and a small aperture. This greatly reduces the cost of the lens. Our newly developed optical-coupling technology is the ultimate form of cooling for the CRT tubes of projection televisions and coupling with the lens and will become the mainstream technology in the future. It is forecast that other manufacturers will also adopt this type of technology. The optical lens section, which is the heart of a projection television, is a hybrid structure with three aspherical plastic lenses and one glass spherical lens. It has higher performance image formation and greater temperature stability than previous televisions. The plastic lenses are all finished with multi-coating to hold down light loss and maximize transparency. This con-tributes greatly to increasing the brightness for a projection television. Previous 3-tube type projection televisions were bothered by low color uniformity, color shift, and low color rela-tive illumination. This model uses three bends

  7. Role of chalcogen vapor annealing in inducing bulk superconductivity in Fe1+yTe1-xSex [How does annealing in chalcogen vapor induce superconductivity in Fe1+yTe-xSex?

    DOE PAGESBeta

    Lin, Wenzhi; Ganesh, P.; Gianfrancesco, Anthony; Wang, Jun; Berlijn, Tom; Maier, Thomas A.; Kalinin, Sergei V.; Sales, Brian C.; Pan, Minghu

    2015-02-01

    Recent investigations have shown that Fe1+yTe1-xSex can be made superconducting by annealing it in Se and O vapors. The current lore is that these chalcogen vapors induce superconductivity by removing the magnetic excess Fe atoms. To investigate this phenomenon we performed a combination of magnetic susceptibility, specific heat and transport measurements together with scanning tunneling microscopy and spectroscopy and density functional theory calculations on Fe1+yTe1-xSex treated with Te vapor. We conclude that the main role of the Te vapor is to quench the magnetic moments of the excess Fe atoms by forming FeTem (m ≥ 1) complexes. We show thatmore » the remaining FeTem complexes are still damaging to the superconductivity and therefore that their removal potentially could further improve superconductive properties in these compounds.« less

  8. Chemical analyses of pore water from boreholes USW SD-6 and USW WT-24, Yucca Mountain, Nevada

    USGS Publications Warehouse

    Yang, I.C.; Peterman, Z.E.; Scofield, K.M.

    2003-01-01

    Analyses of pore water extracted from cores of boreholes USW SD-6 in the central part and USW WT-24 in the northern part of Yucca Mountain, Nevada, show significant vertical and lateral variations in dissolved-ion concentrations. Analyses of samples of only a few milliliters of pore water extracted by uniaxial or triaxial compression and by ultracentrifugation methods from adjacent core samples are generally in agreement, within the analytical error of 10% to 15%. However, the values of silica for water obtained by ultracentrifugation are consistently lower than values for water obtained by compression. The larger concentrations probably are due to localized pressure solution of silicate minerals during compression. The shallower water from core in borehole USW SD-6 was extracted from nonwelded units collectively referred to as the Paintbrush Tuff nonwelded (PTn). The deeper water was from core in both boreholes USW SD-6 and USW WT-24 in the nonwelded units referred to as the Calico Hills nonwelded (CHn). Significant differences in mean dissolved-ion concentrations in pore water between the PTn and CHn are (1) decreases in Ca, Mg, SO4, and NO3 and (2) increases in HCO3 and (Na+K)/(Ca+Mg) ratios. The decrease in NO3 and the increase in HCO3 could be the result of denitrification through the oxidation of organic matter. The decrease in Ca and associated increase in (Na+K)/(Ca+Mg) is the result of ion exchange with zeolites in the CHn in borehole USW WT-24. This effect is not nearly as pronounced in borehole USW SD-6, probably reflecting a smaller amount of zeolitization of the CHn in USW SD-6. Geochemical calculations using the PHREEQC code indicate that the pore water from both boreholes USW SD-6 and USW WT-24 is uniformly undersaturated in anhydrite, gypsum, and amorphous silica, but supersaturated in quartz and chalcedony. The saturation of calcite, aragonite, sepiolite, and dolomite is more variable from sample to sample. ?? 2002 Elsevier Science B.V. All rights

  9. Southern galaxies. VIII - Surface photometry of the SD spiral NGC 7793

    NASA Astrophysics Data System (ADS)

    de Vaucouleurs, G.; Davoust, E.

    1980-08-01

    Detailed surface photometry in blue light of the SA(s)d galaxy NGC 7793, the faintest of the five major members of the Sculptor group, is obtained from photoelectrically calibrated Mount Stromlo and McDonald photographs. The luminosity distribution is dominated by an exponential disk of effective radius αe = 2'.11 = 1.92 kpc contributing 98.6% of the total luminosity BT = 9.51 ± 0.06. The corrected face-on magnitude BT0 = 9.13 corresponds to MT0 = -18.35 at the revised distance Δ = 3.1 Mpc (Appendix C). The spheroidal component visible only in the vicinity of the nucleus can be represented by an r1/4 law of effective radius rIe = 6".0 = 91 pc and total magnitude BTI = 14.13 or 1.4% of the total luminosity of the galaxy. The position angle of the major axis is 97°, the mean axis ratio is q = b/a = 0.61, and the inclination = 53°. The concentration indices C21 = 1.68 and C32 = 1.48 are consistent with the Sd classification. The integrated colors from UBV aperture photometry are essentially constant at = 0.56 ± 0.02, = -0.07 ± 0.02, the corrected face-on colors are (B - V)T0 = 0.46, (U - B)T0 = -0.15 in close agreement with the colors of M33 and the mean values for type Scd. A decomposition of the disk into an underlying old component and a young arm component shows that 65.570 of the total luminosity comes from the old component which has a corrected central luminosity μcα(0) = 21.06 and an effective radius re = 1'.76 = 1.60 kpc. The neutral H I mass MH = 0.67 × 109 Msun corresponds to a hydrogen-luminosity ratio MH/LB = 0.14 which is less than half the average for the morphological type and luminosity class of NGC 7793. The large number of H ii regions and the strength of the Hα emission in the disk suggest that a large fraction of the hydrogen is ionized. The integrated magnitude of the brightest superassociation (Hodge Nr 20) B, = 16.0 ± 0.1 is derived in Appendix A. The effect of resolution on the apparent peak brightness is illustrated in Appendix B

  10. Role of chalcogen vapor annealing in inducing bulk superconductivity in Fe1 +yTe1 -xSex

    NASA Astrophysics Data System (ADS)

    Lin, Wenzhi; Ganesh, P.; Gianfrancesco, Anthony; Wang, Jun; Berlijn, Tom; Maier, Thomas A.; Kalinin, Sergei V.; Sales, Brian C.; Pan, Minghu

    2015-02-01

    Recent investigations have shown that Fe1 +yTe1 -xSex can be made superconducting by annealing it in Se and O vapors. The current lore is that these chalcogen vapors induce superconductivity by removing the magnetic excess Fe atoms. To investigate this phenomenon, we performed a combination of magnetic susceptibility, specific heat, and transport measurements together with scanning tunneling microscopy and spectroscopy and density functional theory calculations on Fe1 +yTe1 -xSex treated with Te vapor. We conclude that the main role of the Te vapor is to quench the magnetic moments of the excess Fe atoms by forming FeTem (m ≥1 ) complexes. We show that the remaining FeTem complexes are still damaging to the superconductivity and therefore that their removal potentially could further improve superconductive properties in these compounds.

  11. Influence of interstitial Fe to the phase diagram of Fe1+yTe1-xSex single crystals.

    PubMed

    Sun, Yue; Yamada, Tatsuhiro; Pyon, Sunseng; Tamegai, Tsuyoshi

    2016-01-01

    Superconductivity (SC) with the suppression of long-range antiferromagnetic (AFM) order is observed in the parent compounds of both iron-based and cuprate superconductors. The AFM wave vectors are bicollinear (π, 0) in the parent compound FeTe different from the collinear AFM order (π, π) in most iron pnictides. Study of the phase diagram of Fe1+yTe1-xSex is the most direct way to investigate the competition between bicollinear AFM and SC. However, presence of interstitial Fe affects both magnetism and SC of Fe1+yTe1-xSex, which hinders the establishment of the real phase diagram. Here, we report the comparison of doping-temperature (x-T) phase diagrams for Fe1+yTe1-xSex (0 ≤ x ≤ 0.43) single crystals before and after removing interstitial Fe. Without interstitial Fe, the AFM state survives only for x < 0.05, and bulk SC emerges from x = 0.05, and does not coexist with the AFM state. The previously reported spin glass state, and the coexistence of AFM and SC may be originated from the effect of the interstitial Fe. The phase diagram of Fe1+yTe1-xSex is found to be similar to the case of the "1111" system such as LaFeAsO1-xFx, and is different from that of the "122" system. PMID:27577047

  12. Pseudogap and proximity effect in the Bi2Te3/Fe1+yTe interfacial superconductor.

    PubMed

    He, M Q; Shen, J Y; Petrović, A P; He, Q L; Liu, H C; Zheng, Y; Wong, C H; Chen, Q H; Wang, J N; Law, K T; Sou, I K; Lortz, R

    2016-01-01

    In the interfacial superconductor Bi2Te3/Fe1+yTe, two dimensional superconductivity occurs in direct vicinity to the surface state of a topological insulator. If this state were to become involved in superconductivity, under certain conditions a topological superconducting state could be formed, which is of high interest due to the possibility of creating Majorana fermionic states. We report directional point-contact spectroscopy data on the novel Bi2Te3/Fe1+yTe interfacial superconductor for a Bi2Te3 thickness of 9 quintuple layers, bonded by van der Waals epitaxy to a Fe1+yTe film at an atomically sharp interface. Our data show highly unconventional superconductivity, which appears as complex as in the cuprate high temperature superconductors. A very large superconducting twin-gap structure is replaced by a pseudogap above ~12 K which persists up to 40 K. While the larger gap shows unconventional order parameter symmetry and is attributed to a thin FeTe layer in proximity to the interface, the smaller gap is associated with superconductivity induced via the proximity effect in the topological insulator Bi2Te3. PMID:27587000

  13. Effects of annealing, acid and alcoholic beverages on Fe1+yTe0.6Se0.4

    NASA Astrophysics Data System (ADS)

    Sun, Y.; Taen, T.; Tsuchiya, Y.; Shi, Z. X.; Tamegai, T.

    2013-01-01

    We have systematically investigated and compared different methods to induce superconductivity in the iron chalcogenide Fe1+yTe0.6Se0.4, including annealing in a vacuum, N2, O2 and I2 atmospheres and immersing samples into acid and alcoholic beverages. Vacuum and N2 annealing are proved to be ineffective in inducing superconductivity in a Fe1+yTe0.6Se0.4 single crystal. Annealing in O2 and I2 and immersion in acid and alcoholic beverages can induce superconductivity by oxidizing the excess Fe in the sample. Superconductivity in O2 annealed samples is of a bulk nature, while I2, acid and alcoholic beverages can only induce superconductivity near the surface. By comparing the different effects of O2, I2, acid and alcoholic beverages we propose a scenario to explain how the superconductivity is induced in the non-superconducting as-grown Fe1+yTe0.6Se0.4.

  14. Effects of Pnictogen Atmosphere Annealing on Fe1+yTe0.6Se0.4

    NASA Astrophysics Data System (ADS)

    Yamada, Tatsuhiro; Sun, Yue; Pyon, Sunseng; Tamegai, Tsuyoshi

    2016-02-01

    It has been clarified that bulk superconductivity in Fe1+yTe0.6Se0.4 can be induced by annealing in an appropriate atmosphere to remove the harmful effects of excess iron. In order to clarify the details of the annealing process, we studied the changes in the physical properties and reaction products of Fe1+yTe0.6Se0.4 annealed in pnictogen (P, As, Sb) atmospheres. Crystals annealed in a pnictogen atmosphere show bulk superconductivity and the values of Tc and Jc are about 14 K and (2-4) × 105 A/cm2 (2 K, self-field), respectively. It is also found that the reaction rate increases with the increase in the saturated vapor pressure of the pnictogen. Unexpectedly, the reaction products of Fe1+yTe0.6Se0.4 after annealing in a P atmosphere mainly consist of FeTe2. In addition, the amount of P required to obtain the optimal Tc is much smaller than the amount of excess iron, which is similar to the case of oxygen annealing. P, oxygen, and to some extent As could serve as catalysts to form FeTe2 to remove excess iron.

  15. Pseudogap and proximity effect in the Bi2Te3/Fe1+yTe interfacial superconductor

    PubMed Central

    He, M. Q.; Shen, J. Y.; Petrović, A. P.; He, Q. L.; Liu, H. C.; Zheng, Y.; Wong, C. H.; Chen, Q. H.; Wang, J. N.; Law, K. T.; Sou, I. K.; Lortz, R.

    2016-01-01

    In the interfacial superconductor Bi2Te3/Fe1+yTe, two dimensional superconductivity occurs in direct vicinity to the surface state of a topological insulator. If this state were to become involved in superconductivity, under certain conditions a topological superconducting state could be formed, which is of high interest due to the possibility of creating Majorana fermionic states. We report directional point-contact spectroscopy data on the novel Bi2Te3/Fe1+yTe interfacial superconductor for a Bi2Te3 thickness of 9 quintuple layers, bonded by van der Waals epitaxy to a Fe1+yTe film at an atomically sharp interface. Our data show highly unconventional superconductivity, which appears as complex as in the cuprate high temperature superconductors. A very large superconducting twin-gap structure is replaced by a pseudogap above ~12 K which persists up to 40 K. While the larger gap shows unconventional order parameter symmetry and is attributed to a thin FeTe layer in proximity to the interface, the smaller gap is associated with superconductivity induced via the proximity effect in the topological insulator Bi2Te3. PMID:27587000

  16. Fatty Acid Composition of Adipose Tissues in Obese Mice and SD Rats Fed with Isaria sinclairii Powder

    PubMed Central

    Ahn, Mi Young; Seo, Yun Jung; Ji, Sang Deok; Han, Jea Woong; Hwang, Jae Sam; Yun, Eun Young

    2010-01-01

    Isaria sinclairii (Cicada Dongchunghacho) was studied as a potential crude natural food in powdered form. The role of tissue fatty acids in relation to the anti-obesity effects of I. sinclairii (IS) was examined by feeding the powder to SD rats ad libitum at 0, 1.25, 2.5, 5 and 10% (calculated about 8 g/kg) of the feed for a period of 3 months and 6 months. The fatty acid composition profile as indicated GC-MS, showed significantly slight dose-dependent increases in the levels of unsaturated fatty acids, particularly, arachidonic acid (C20: 4n6) , oleic acid, linoleic acid, eicosadienoic acid, eicosapentaenoic acid (EPA) (C20: 5) concentration in the the ad libitum IS-fed groups compared to the control group in SD abdominal fat over 6 month period. Over viewing of the SD and Ob mice treated Isaria sinclairii powder; there were increases in the single (mono) unsaturated fatty acids ratio but decreases in polyunsaturated fatty acid. In IS-fed groups in proportion to the treatment period, this Dongchunghacho also induced an increase in the level of same result of unsaturated fatty acid in C57BL/6 obese (ob/ob) mice over a 6-month period treatment compared to those given 10% dry mulberry leaf powder (ML) or silkworm powder mixed with the standard diet. PMID:24278523

  17. Influence of the Al concentration on the electronic properties of coupled and uncoupled AlxGa1-xAs/AlAs/AlyGa1-yAs double quantum wells

    NASA Astrophysics Data System (ADS)

    Armas, L. E. G.; da Silva, E. C. F.; Duarte, C. A.; Pagnossin, I. R.; Quivy, A. A.; Menezes, J. W.; Jacinto, C.; Seabra, A. C.; Gusev, G. M.

    2014-07-01

    Shubnikov-de Haas (SdH) and Hall measurements have been used to investigate the electron densities and mobilities in a pair of adjacent two-dimensional electron gases (2DEGs), which were confined in coupled and uncoupled AlxGa1-xAs/AlAs/AlyGa1-yAs double quantum wells (DQWs), as a function of front-gate voltage (Vg). The electron densities and mobilities of the first and second sub-bands were determined using the fast Fourier transform (FFT) in both coupled and uncoupled samples, named S1, S2 and S3, which have different aluminum (Al) content in each well. Sample S1 was illuminated in order to reach the coupled behavior. The electronic properties of the samples have been compared, showing that the electron density and mobility decrease with increasing Al content within the quantum wells (QWs). The last fact was attributed to the alloy scattering in the AlxGa1-xAs quantum well.

  18. Using asymmetry analysis to reduce normal variability of Spectral Domain Optical Coherence Tomography (SD-OCT) macular thickness

    NASA Astrophysics Data System (ADS)

    Alluwimi, Muhammed Saad

    Purpose: To investigate the use of asymmetry analysis to reduce normal between-subject variability of macular thickness measurements using SD-OCT. Methods: 63 volunteers free of eye disease were recruited: 33 young subjects (ages 21 to 35 years with mean and SD of 25 +/- 1.7), and 30 older subjects (ages 45 to 85 years with mean and SD of 66.7 +/- 9.0). All participants passed a comprehensive ophthalmic examination within the past two years. Macular images were gathered with the Spectralis OCT (V 5.4, Heidelberg Engineering, GmbH). The overlay 8x8 grid was manually centered on the fovea and aligned with the foveal-disc axis, then divided into five zones per hemifield following the method of Um et al (2012 IOVS 53:1139); asymmetry was computed as the difference between superior and inferior zone thicknesses. We assumed that the lowest variation and the highest density of ganglion cells will be found ~3° to 6° from the foveal center, corresponding to zones 1 and 2. For each zone and age group, between-subject standard deviations (SDs) were compared for retinal thickness (RT) versus asymmetry using an F-test. To account for repeated measures, a probability of p < 0.0125 was required for statistical significance. Axial length (AL) and corneal curvature (CC) were measured with an IOLMaster by the same operator and during the same imaging session. Results: For OD, asymmetry analysis reduced between-subject variability in zones 1 and 2 in both groups (F > 3.2, p < 0.001). SD for zone 1 dropped from 12.0 to 3.0 mum in the young group and from 11.7 to 2.6 mum in the older group. SD for zone 2 dropped from 13.6 to 5.3 mum (young) and from 11.1 to 5.8 mum (older). Combining all subjects, neither RT nor asymmetry showed a strong correlation with AL or CC (R2 < 0.01). Analysis for OS yielded the same pattern of results, as did asymmetry analyses between eyes (F > 3.8, p < 0.0001). Conclusions: Asymmetry analysis reduced between-subject variability. These findings demonstrate

  19. The qSD12 Underlying Gene Promotes Abscisic Acid Accumulation in Early Developing Seeds to Induce Primary Dormancy in Rice

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Seeds acquire primary dormancy during their development and the phytohormone abscisic acid (ABA) is considered to play a role in inducing the dormancy. qSD12 is a major seed dormancy QTL identified from weedy rice. This research was conducted to identify qSD12 candidate genes, isolate the candidat...

  20. Electron g-factor in bulk Ga1-xInxAsySb1-y/GaSb quaternary alloy and in GaSb/Ga1-xInxAsySb1-y/GaSb Spherical quantum dots

    NASA Astrophysics Data System (ADS)

    Sánchez-Cano, R.; Porras-Montenegro, N.

    2011-12-01

    Secure quantum communications require an entanglement-preserving photo-detector in which quantum information is transmitted by photon polarization through an mid infrared optical fiber system and then transferred to electron spin in a optoelectronic semiconductor device. Using interpolation scheme we have investigated the electron g-factor in bulk Ga1-xInxAsySb1-y quaternary alloy matched to GaSb as a function of Indium and Arsenic concentration on the complete range 0≤x,y≤1. A specific g-factor as a function of the radius in a spherical GaSb/Ga1-xInxAsySb1-y/GaSb quantum dot heterostructure is calculated. Furthermore, we present calculations of the energy states including the Zeeman effect on the electrons confined in quaternary heterostructure quantum dots, with a parabolic confining potential under applied magnetic fields. Our calculations have been worked out by using interpolating methods to find the band gap as a function of the Indium concentration in order to determine the conduction band-offset at room temperature in GaSb/Ga1-xInxAsySb1-y/GaSb heterostructure, within the effective-mass approximation. Experimental or theoretical electron g-factor, spin-orbit splitting Δso, and coupling matrix elements Ep = (2/m0)||2 value between the states of the lowest conduction band Γ6 and the upper valence bands Γ8 for Ga1-xInxAsySb1-y/GaSb quaternary alloy are not readily available. Our predictions show that electron g-factor values are in the range between the electron g-factor measured in bulk GaSb when x→0 (g = -9.25) and that measured in InAs when x→1 (g = -18.08), but there is a remarkable minimum in the g-factor value (g≃-23.14) at x≃0.67.

  1. Cellulose film regenerated from Styela clava tunics have biodegradability, toxicity and biocompatibility in the skin of SD rats.

    PubMed

    Song, Sung Hwa; Kim, Ji Eun; Lee, Young Ju; Kwak, Moon Hwa; Sung, Geum Yong; Kwon, Soon Hong; Son, Hong Joo; Lee, Hee Seob; Jung, Young Jin; Hwang, Dae Youn

    2014-06-01

    Cellulose is one of the most widespread biomolecules in nature and has been exploited in various applications including scaffolding, tissue engineering, and tissue formation. To evaluate the biocompatibility of cellulose film manufactured from Styela clava tunics (SCT-CF), these films were implanted in Sprague-Dawley (SD) rats for various lengths of time, after which they were subjected to mechanical and biological analyses. The cellulose powders (12-268 m) obtained from SCT was converted into films via casting methods without adding any additives. SCT-CF contained about 98 % α-cellulose and very low concentrations of ββ-cellulose. Additionally, the crystallinity index (CrI) of SCT-CF was lower (10.71 %) than that of wood pulp-cellulose films (WP-CF) (33.78 %). After implantation for 90 days, the weight loss and formation of surface corrugations were greater in SCT-CF than that of WP-CF, while the surface roughness was significantly higher in WP-CF than SCT-CF. However, there were no differences in the number of white blood cells between SCT-CF implanted rats and vehicle implanted rats. The level of metabolic enzymes representing liver and kidney toxicity in the serum of SCT-CF implanted rats was maintained at levels consistent with vehicle implanted rats. Moreover, no significant alteration of the epidermal hyperplasia, inflammatory cell infiltration, redness, and edema were observed in SD rats implanted with SCT-CF. Taken together, these results indicate that SCT-CF showed good degradability and non-toxicity without inducing an immune response in SD rats. Further, the data presented here constitute strong evidence that SCT-CF has the potential for use as a powerful biomaterial for medical applications including stitching fiber, wound dressing, scaffolding, absorbable hemostats and hemodialysis membrane. PMID:24577945

  2. The NPOESS Preparatory Project Science Data Segment (SDS) Data Depository and Distribution Element (SD3E) System Architecture

    NASA Technical Reports Server (NTRS)

    Ho, Evelyn L.; Schweiss, Robert J.

    2008-01-01

    The National Polar-orbiting Operational Environmental Satellite System (NPOESS) Preparatory Project (NPP) Science Data Segment (SDS) will make daily data requests for approximately six terabytes of NPP science products for each of its six environmental assessment elements from the operational data providers. As a result, issues associated with duplicate data requests, data transfers of large volumes of diverse products, and data transfer failures raised concerns with respect to the network traffic and bandwidth consumption. The NPP SDS Data Depository and Distribution Element (SD3E) was developed to provide a mechanism for efficient data exchange, alleviate duplicate network traffic, and reduce operational costs.

  3. Prenylated indolediketopiperazine peroxides and related homologues from the marine sediment-derived fungus Penicillium brefeldianum SD-273.

    PubMed

    An, Chun-Yan; Li, Xiao-Ming; Li, Chun-Shun; Xu, Gang-Ming; Wang, Bin-Gui

    2014-02-01

    Three new indolediketopiperazine peroxides, namely, 24-hydroxyverruculogen (1), 26-hydroxyverruculogen (2), and 13-O-prenyl-26-hydroxyverruculogen (3), along with four known homologues (4-7), were isolated and identified from the culture extract of the marine sediment-derived fungus Penicillium brefeldianum SD-273. Their structures were determined based on the extensive spectroscopic analysis and compound 1 was confirmed by X-ray crystallographic analysis. The absolute configuration of compounds 1-3 was determined using chiral HPLC analysis of their acidic hydrolysates. Each of the isolated compounds was evaluated for antibacterial and cytotoxic activity as well as brine shrimp (Artemia salina) lethality. PMID:24473173

  4. Complete Nucleotide Sequence of cfr-Carrying IncX4 Plasmid pSD11 from Escherichia coli

    PubMed Central

    Sun, Jian; Deng, Hui; Li, Liang; Chen, Mu-Ya; Fang, Liang-Xing; Yang, Qiu-E

    2014-01-01

    We report the complete nucleotide sequence of a plasmid carrying the multiresistance gene cfr. This plasmid was isolated from an Escherichia coli strain of swine origin in 2011. This 37,672-bp plasmid, pSD11, had an IncX4 backbone similar to those of the IncX4 plasmids obtained from the United States and Australia, in which the cfr gene was flanked by two copies of IS26 and a truncated Tn1331 was inserted. PMID:25403661

  5. Prenylated Indolediketopiperazine Peroxides and Related Homologues from the Marine Sediment-Derived Fungus Penicillium brefeldianum SD-273

    PubMed Central

    An, Chun-Yan; Li, Xiao-Ming; Li, Chun-Shun; Xu, Gang-Ming; Wang, Bin-Gui

    2014-01-01

    Three new indolediketopiperazine peroxides, namely, 24-hydroxyverruculogen (1), 26-hydroxyverruculogen (2), and 13-O-prenyl-26-hydroxyverruculogen (3), along with four known homologues (4–7), were isolated and identified from the culture extract of the marine sediment-derived fungus Penicillium brefeldianum SD-273. Their structures were determined based on the extensive spectroscopic analysis and compound 1 was confirmed by X-ray crystallographic analysis. The absolute configuration of compounds 1–3 was determined using chiral HPLC analysis of their acidic hydrolysates. Each of the isolated compounds was evaluated for antibacterial and cytotoxic activity as well as brine shrimp (Artemia salina) lethality. PMID:24473173

  6. [Metabolomic approach to evaluating the effect of the mixed decoction of kelp and licorice on system metabolism of SD rats].

    PubMed

    Sun, Run-bin; Yu, Xiao-yi; Mao, Yong; Ge, Chun; Yang Na; A, Ji-ye; Tang, Yu-ping; Duan, Jin-ao; Ma, Zi-teng; Wu, Xu-tong; Zhu, Xuan-xuan; Wang, Guang-ji

    2015-03-01

    The aim of the study is to evaluate the effects of the single and mixed decoction of Thallus laminariae (kelp) and Glycyrrhiza glabra (licorice) on the metabolism and their difference. The mixed decoction of kelp and licorice and the single decoction were made and intragastrically administered to the SD rats. The effect on system metabolism, the toxicity of liver and kidney were assessed by GC-MS profiling of the endogenous molecules in serum, routine biochemical assays and histographic inspection of tissues from SD rats, separately. The mixed decoction of kelp and licorice induced more obvious pathological abnormalities in SD rats than a single decoction of kelp, while the extracts of licorice did not show any pathological change. Neither the mixed, nor the single decoction showed abnormal histopathology. After intragastric administration of extracts for 5 days, the mixed decoction induced a decrease of ALT (no significant change in the groups of single decoction) and an increase of BUN (so did the single decoction of kelp). Metabolomic profile of the molecules in serum revealed that the metabolic patterns were all obviously affected for the three groups, i.e., the mixed and single decoction of kelp and licorice. The rats given with the single decoction of kelp showed a similar pattern to that of the mixed decoction, indicating that the kelp primarily contributed the perturbation of metabolism for the mixed decoction. All three groups induced a decrease of branched chain amino acids, TCA cycle intermediates and glycolysis intermediates (e.g., pyruvic acid and lactic acid) and an increase of 3-hydroxybutyric acid. Kelp decoction showed stronger potential in reducing TCA cycle intermediates and glycolysis intermediates than the other two groups, while the levels of branched chain amino acids were the lowest after licorice extracts were given. These results suggested that the effect of the mixed decoction on metabolism was closely associated with both kelp and

  7. New extrapolation method for low-lying states of nuclei in the sd and the pf shells

    SciTech Connect

    Shen, J. J.; Zhao, Y. M.; Arima, A.; Yoshinaga, N.

    2011-04-15

    We study extrapolation approaches to evaluate energies of low-lying states for nuclei in the sd and pf shells, by sorting the diagonal matrix elements of the nuclear shell-model Hamiltonian. We introduce an extrapolation method with perturbation and apply our new method to predict both low-lying state energies and E2 transition rates between low-lying states. Our predicted results arrive at an accuracy of the root-mean-squared deviations {approx}40-60 keV for low-lying states of these nuclei.

  8. Phase conversion from hexagonal CuS(y)Se(1-y) to cubic Cu(2-x)S(y)Se(1-y): composition variation, morphology evolution, optical tuning, and solar cell applications.

    PubMed

    Xu, Jun; Yang, Xia; Yang, Qingdan; Zhang, Wenjun; Lee, Chun-Sing

    2014-09-24

    In this work, we report a simple and low-temperature approach for the controllable synthesis of ternary Cu-S-Se alloys featuring tunable crystal structures, compositions, morphologies, and optical properties. Hexagonal CuS(y)Se(1-y) nanoplates and face centered cubic (fcc) Cu(2-x)S(y)Se(1-y) single-crystal-like stacked nanoplate assemblies are synthesized, and their phase conversion mechanism is well investigated. It is found that both copper content and chalcogen composition (S/Se atomic ratio) of the Cu-S-Se alloys are tunable during the phase conversion process. Formation of the unique single-crystal-like stacked nanoplate assemblies is resulted from oriented stacking coupled with the Ostwald ripening effect. Remarkably, optical tuning for continuous red shifts of both the band-gap absorption and the near-infrared localized surface plasmon resonance are achieved. Furthermore, the novel Cu-S-Se alloys are utilized for the first time as highly efficient counter electrodes (CEs) in quantum dot sensitized solar cells (QDSSCs), showing outstanding electrocatalytic activity for polysulfide electrolyte regeneration and yielding a 135% enhancement in power conversion efficiency (PCE) as compared to the noble metal Pt counter electrode. PMID:25162581

  9. The superconducting transition temperatures of Fe1+xSe1-y, Fe1+xSe1-yTey and (K/Rb/Cs)zFe2-xSe2

    NASA Astrophysics Data System (ADS)

    Harshman, Dale R.; Fiory, Anthony T.

    2012-04-01

    In a recent contribution to this journal, it was shown that the transition temperatures of optimal high-TC compounds obey the algebraic relation {T}_{{C0}}={k}_{{B}}^{-1}\\beta /\\ell \\zeta , where ℓ is related to the mean spacing between interacting charges in the layers, ζ is the distance between interacting electronic layers, β is a universal constant and kB is Boltzmann’s constant. The equation was derived assuming pairing based on interlayer Coulomb interactions between physically separated charges. This theory was initially validated for 31 compounds from five different high-TC families (within an accuracy of ±1.37 K). Herein we report the addition of Fe1+xSe1-y and Fe1+xSe1-yTey (both optimized under pressure) and AzFe2-xSe2 (for A = K, Rb or Cs) to the growing list of Coulomb-mediated superconducting compounds in which TC0 is determined by the above equation. Doping in these materials is accomplished through the introduction of excess Fe and/or Se deficiency, or a combination of alkali metal and Fe vacancies. Consequently, a very small number of vacancies or interstitials can induce a superconducting state with a substantial transition temperature. The confirmation of the above equation for these Se-based Fe chalcogenides increases to six the number of superconducting families for which the transition temperature can be accurately predicted.

  10. New ex-ovo colorectal-cancer models from different SdFFF-sorted tumor-initiating cells.

    PubMed

    Mélin, Carole; Perraud, Aurélie; Christou, Niki; Bibes, Romain; Cardot, Philippe; Jauberteau, Marie-Odile; Battu, Serge; Mathonnet, Muriel

    2015-11-01

    Despite effective treatments, relapse of colorectal cancer (CRC) is frequent, in part caused by the existence of tumor-initiating cells (TICs). Different subtypes of TICs, quiescent and activated, coexist in tumors, defining the tumor aggressiveness and therapeutic response. These subtypes have been sorted by hyperlayer sedimentation field-flow fractionation (SdFFF) from WiDr and HCT116 cell lines. On the basis of a new strategy, including TIC SdFFF sorting, 3D Matrigel amplification, and grafting of corresponding TIC colonies on the chick chorioallantoic membrane (CAM), specific tumor matrices could be obtained. If tumors had similar architectural structure with vascularization by the host system, they had different proliferative indices in agreement with their initial quiescent or activated state. Protein analysis also revealed that tumors obtained from a population enriched for "activated" TICs lost "stemness" properties and became invasive. In contrast, tumors obtained from a population enriched for "quiescent" TICs kept their stemness properties and seemed to be less proliferative and invasive. Then, it was possible to produce different kinds of tumor which could be used as selective supports to study carcinogenesis and therapy sensitivity. PMID:26427501

  11. High-resolution spectrometer: solution to the axial resolution and ranging depth trade-off of SD-OCT

    NASA Astrophysics Data System (ADS)

    Marvdashti, Tahereh; Lee, Hee Yoon; Ellerbee, Audrey K.

    2013-03-01

    We demonstrate a cross-dispersed spectrometer for Spectral Domain Optical Coherence Tomography (SD-OCT). The resolution of a conventional SD-OCT spectrometer is limited by the available sizes of the linear array detectors. The adverse consequences of this finite resolution is a trade-off between achieving practical field of view (i.e. ranging depth) and maintaining high axial resolution. Inspired by spectrometer designs for astronomy, we take advantage of very high pixel-density 2D CCD arrays to map a single-shot 2D spectrum to an OCT A-scan. The basic system can be implemented using a high-resolution Echelle grating crossed with a prism in a direction orthogonal to the dispersion axis. In this geometry, the interferometric light returning from the OCT system is dispersed in two dimensions; the resulting spectrum can achieve more pixels than a traditional OCT spectrometer (which increases the ranging depth) and maintains impressive axial resolution because of the broad bandwidth of the detected OCT light. To the best of our knowledge, we present the first demonstration of OCT data using an Echelle-based cross-dispersed spectrometer. Potential applications for such a system include high-resolution imaging of the retina or the anterior segment of the eye over extended imaging depths and small animal imaging.

  12. Electronic disorder and magnetic-field-induced superconductivity enhancement in Fe1+y(Te1-xSex)

    NASA Astrophysics Data System (ADS)

    Hu, Jin; Liu, Tijiang; Qian, Bin; Mao, Zhiqiang

    2012-02-01

    The iron chalcogenide Fe1+y(Te1-xSex) superconductor system exhibits a unique electronic and magnetic phase diagram distinct from those seen in iron pnictides: bulk superconductivity does not appear immediately following the suppression of long-range (π,0) AFM order. Instead, an intermediate phase with weak charge carrier localization appears between AFM order and bulk superconductivity (Liu et al., Nat. Mater. 9, 719 (2010)). In this talk, we report our recent studies on the relationship between the normal state and superconducting properties in Fe1+y(Te1-xSex). We show that the superconducting volume fraction VSC and normal state metallicity significantly increase while the normal state Sommerfeld coefficient γ and Hall coefficient RH drop drastically with increasing Se content in the underdoped superconducting region. Additionally, VSC is surprisingly enhanced by magnetic field in heavily underdoped superconducting samples. The implications of these results will be discussed. Our analyses suggest that the suppression of superconductivity in the underdoped region is associated with electronic disorder caused by incoherent magnetic scattering arising from (π,0) magnetic fluctuations.

  13. Analysis of surface defects in Si1-y C y epilayers formed by the oversaturation of carbon

    NASA Astrophysics Data System (ADS)

    Colston, Gerard; Myronov, Maksym; Rhead, Stephen; Leadley, David

    2015-11-01

    Strained Si1-y C y epilayers have been grown on Si (001) by reduced pressure chemical vapor deposition, using low-cost precursors disilane and trimethylsilane. Substitutional C incorporation has been achieved in strained epilayers up to y = 1.5%, while higher C content of at least 2.4% is observed in relaxed layers. These results are comparable to the highest concentrations achieved using more highly reactive, but expensive, precursors. These relatively high C content epilayers were found to form defects throughout growth attributed to the clustering of C adatoms, which result in localized accelerated amorphous growth and, consequently, hillocks forming on the epilayer surface. The formation, size and distribution of these surface defects has been analyzed through the use of various microscopic techniques. The size and density of these structural defects increases with both C content and epilayer thickness. In our layers of fixed growth time, substitutional C compositions above 1.5% causes hillocks to fuse on the surface; subsequently amorphous growth occurs, which forms an amorphous layer over the crystalline Si1-y C y epilayer and hence prevents further epitaxy or reliable device fabrication. The results of this investigation suggest that substitutional C composition of below 1.5% could be achieved without the need for expensive and volatile precursors or complex growth processes, assuming sufficiently thin layers are grown.

  14. Direct evidence of the fermi-energy-dependent formation of Mn interstitials in modulation doped Ga1-yAlyAs/Ga1-xMnxAs/Ga1-yAlyAs heterostructures

    SciTech Connect

    Yu, K.M.; Walukiewicz, W.; Wojtowicz, T.; Lim, W.L.; Liu, X.; Dobrowolska, M.; Furdyna, J.K.

    2004-01-30

    Using ion channeling techniques, we investigate the lattice locations of Mn in Ga{sub 1-x}Mn{sub x}As quantum wells between Be-doped Ga{sub 1-y}Al{sub y}As barriers. The earlier results showed that the Curie temperature T{sub C} depends on the growth sequence of the epitaxial layers. A lower T{sub C} was found in heterostructures in which the Ga{sub 1-x}Mn{sub x}As layer is grown after the modulation-doped barrier. Here we provide direct evidence that this reduction in T{sub C} is directly correlated with an increased formation of magnetically inactive Mn interstitials. The formation of interstitials is induced by a shift of the Fermi energy as a result of the transfer of holes from the barrier to the quantum well during the growth.

  15. Activation of c-myb by 5' retrovirus promoter insertion in myeloid neoplasms is dependent upon an intact alternative splice donor site (SD') in gag

    SciTech Connect

    Ramirez, Jean Marie; Houzet, Laurent; Koller, Richard; Bies, Juraj; Wolff, Linda; Mougel, Marylene . E-mail: mmougel@univ-montp1.fr

    2004-12-20

    Alternative splicing in Mo-MuLV recruits a splice donor site, SD', within the gag that is required for optimal replication in vitro. Remarkably, this SD' site was also found to be utilized for production of oncogenic gag-myb fusion RNA in 100% of murine-induced myeloid leukemia (MML) in pristane-treated BALB/c mice. Therefore, we investigated the influence of silent mutations of SD' in this model. Although there was no decrease in the overall incidence of disease, there was a decrease in the incidence of myeloid leukemia with a concomitant increase in lymphoid leukemia. Importantly, there was a complete lack of myeloid tumors associated with 5' insertional mutagenic activation of c-myb, suggesting the specific requirement of the SD' site in this mechanism.

  16. Activation of c-myb by 5' retrovirus promoter insertion in myeloid neoplasms is dependent upon an intact alternative splice donor site (SD') in gag.

    PubMed

    Ramirez, Jean Marie; Houzet, Laurent; Koller, Richard; Bies, Juraj; Wolff, Linda; Mougel, Marylène

    2004-12-20

    Alternative splicing in Mo-MuLV recruits a splice donor site, SD', within the gag that is required for optimal replication in vitro. Remarkably, this SD' site was also found to be utilized for production of oncogenic gag-myb fusion RNA in 100% of murine-induced myeloid leukemia (MML) in pristane-treated BALB/c mice. Therefore, we investigated the influence of silent mutations of SD' in this model. Although there was no decrease in the overall incidence of disease, there was a decrease in the incidence of myeloid leukemia with a concomitant increase in lymphoid leukemia. Importantly, there was a complete lack of myeloid tumors associated with 5' insertional mutagenic activation of c-myb, suggesting the specific requirement of the SD' site in this mechanism. PMID:15567434

  17. Antisite-disorder, magnetic and thermoelectric properties of Mo-rich Sr2Fe1-yMo1+yO6 (0 ≤y≤ 0.2) double perovskites.

    PubMed

    Popuri, Srinivasa R; Redpath, Debbie; Chan, Gavin; Smith, Ronald I; Cespedes, Oscar; Bos, Jan-Willem G

    2015-06-21

    Structure analysis using X-ray and neutron powder diffraction and elemental mapping has been used to demonstrate that nominal A-site deficient Sr(2-x)FeMoO(6-δ) (0 ≤x≤ 0.5) compositions form as Mo-rich Sr(2)Fe(1-y)Mo(1+y)O(6) (0 ≤y≤ 0.2) perovskites at high temperatures and under reducing atmospheres. These materials show a gradual transition from the Fe and Mo rock salt ordered double perovskite structure to a B-site disordered arrangement. Analysis of the fractions of B-O-B' linkages revealed a gradual increase in the number of Mo-O-Mo linkages at the expense of the ferrimagnetic (FIM) Fe-O-Mo linkages that dominate the y = 0 material. All samples contain about 10-15% antiferromagnetic (AF) Fe-O-Fe linkages, independent of the degree of B-site ordering. The magnetic susceptibility of the y = 0.2 sample is characteristic of a small domain ferrimagnet (T(c)∼ 250 K), while room temperature neutron powder diffraction demonstrated the presence of G-type AF ordering linked to the Fe-O-Fe linkages (m(Fe) = 1.25(7)μ(B)). The high temperature thermoelectric properties are characteristic of a metal with a linear temperature dependence of the Seebeck coefficient, S (for all y) and electrical resistivity ρ (y≥ 0.1). The largest thermoelectric power factor S(2)/ρ = 0.12 mW m(-1) K(-1) is observed for Sr(2)FeMoO(6) at 1000 K. PMID:25501989

  18. Complete Genome Sequence of Herbinix luporum SD1D, a New Cellulose-Degrading Bacterium Isolated from a Thermophilic Biogas Reactor

    PubMed Central

    Koeck, Daniela E.; Maus, Irena; Wibberg, Daniel; Winkler, Anika; Zverlov, Vladimir V.; Liebl, Wolfgang; Pühler, Alfred; Schwarz, Wolfgang H.

    2016-01-01

    A novel cellulolytic bacterial strain was isolated from an industrial-scale biogas plant. The 16S rRNA gene sequence of the strain SD1D showed 96.4% similarity to Herbinix hemicellulosilytica T3/55T, indicating a novel species within the genus Herbinix (family Lachnospiraceae). Here, the complete genome sequence of Herbinix luporum SD1D is reported. PMID:27445379

  19. Comparison of the Abilities of SD-OCT and SS-OCT in Evaluating the Thickness of the Macular Inner Retinal Layer for Glaucoma Diagnosis

    PubMed Central

    Lee, Kyoung Min; Lee, Eun Ji; Kim, Tae-Woo; Kim, Hyunjoong

    2016-01-01

    Purpose To compare the abilities of spectral-domain optical coherence tomography (OCT) (SD-OCT; Spectralis, Heidelberg Engineering) and swept-source OCT (SS-OCT; DRI-OCT1 Atlantis system, Topcon) for analyzing the macular inner retinal layers in diagnosing glaucoma. Methods The study included 60 patients with primary open-angle glaucoma (POAG) and 60 healthy control subjects. Macular cube area was scanned using SD-OCT and SS-OCT on the same day to assess the thicknesses of the macular retinal nerve fiber layer (mRNFL), ganglion cell layer plus inner plexiform layer (GCIPL), and total retinal layer in nine subfields defined by the Early Treatment Diabetic Retinopathy Study (ETDRS). The abilities of the parameters to discriminate between the POAG and control groups were assessed using areas under the receiver operating characteristic curves (AUCs). Results Glaucoma-associated mRNFL and GCIPL thinning was more common in the outer zones than inner zones for both SD-OCT and SS-OCT. The mRNFL and GCIPL measurements showed distinct pattern differences between SD-OCT and SS-OCT in each ETDRS subfield. Although the glaucoma-diagnosis ability was comparable between SD-OCT and SS-OCT for most of the parameters, AUC was significantly larger for SD-OCT measurements of the GCIPL thickness in the outer temporal zones (p = 0.003) and of the mRNFL thickness in the outer nasal zones (p = 0.001), with the former having the largest AUC for discriminating POAG from healthy eyes (AUC = 0.894). Conclusion Spectralis SD-OCT and DRI SS-OCT have similar glaucoma-diagnosis abilities based on macular inner layer thickness analysis. However, Spectralis SD-OCT was potentially superior to DRI SS-OCT in detecting GCIPL thinning in the outer temporal zone, where the glaucomatous damage predominantly occurs. PMID:26812064

  20. Complete Genome Sequence of Herbinix luporum SD1D, a New Cellulose-Degrading Bacterium Isolated from a Thermophilic Biogas Reactor.

    PubMed

    Koeck, Daniela E; Maus, Irena; Wibberg, Daniel; Winkler, Anika; Zverlov, Vladimir V; Liebl, Wolfgang; Pühler, Alfred; Schwarz, Wolfgang H; Schlüter, Andreas

    2016-01-01

    A novel cellulolytic bacterial strain was isolated from an industrial-scale biogas plant. The 16S rRNA gene sequence of the strain SD1D showed 96.4% similarity to Herbinix hemicellulosilytica T3/55(T), indicating a novel species within the genus Herbinix (family Lachnospiraceae). Here, the complete genome sequence of Herbinix luporum SD1D is reported. PMID:27445379

  1. Supercontinuum generation in nonlinear fibers using high-energy figure-of-eight mode-locked fiber laser for SD-OCT application

    NASA Astrophysics Data System (ADS)

    Xu, Bo; Nagata, Tsubasa; Yamashita, Shinji

    2014-05-01

    Generation of flat and broadband supercontinum is demonstrated in an all fiber system using the high-energy noise-like pulses from a stable figure-of-eight fiber laser and nonlinear fibers. This SC source is successfully applied to the spectral domain optical coherence tomography (SD-OCT). The axial resolution is significantly improved compared with the case of the superluminescent diode source. SD-OCT imaging is also demonstrated.

  2. The sexually dimorphic on the Y-chromosome gene (sdY) is a conserved male-specific Y-chromosome sequence in many salmonids

    PubMed Central

    Yano, Ayaka; Nicol, Barbara; Jouanno, Elodie; Quillet, Edwige; Fostier, Alexis; Guyomard, René; Guiguen, Yann

    2013-01-01

    All salmonid species investigated to date have been characterized with a male heterogametic sex-determination system. However, as these species do not share any Y-chromosome conserved synteny, there remains a debate on whether they share a common master sex-determining gene. In this study, we investigated the extent of conservation and evolution of the rainbow trout (Oncorhynchus mykiss) master sex-determining gene, sdY (sexually dimorphic on the Y-chromosome), in 15 different species of salmonids. We found that the sdY sequence is highly conserved in all salmonids and that sdY is a male-specific Y-chromosome gene in the majority of these species. These findings demonstrate that most salmonids share a conserved sex-determining locus and also strongly suggest that sdY may be this conserved master sex-determining gene. However, in two whitefish species (subfamily Coregoninae), sdY was found both in males and females, suggesting that alternative sex-determination systems may have also evolved in this family. Based on the wide conservation of sdY as a male-specific Y-chromosome gene, efficient and easy molecular sexing techniques can now be developed that will be of great interest for studying these economically and environmentally important species. PMID:23745140

  3. OD(X/sup 2/II) and SD(X/sup 2/II) from reactions of D atoms with OCS under bulk and precursor geometry limited conditions

    SciTech Connect

    Haeusler, D.; Rice, J.; Wittig, C.

    1987-10-08

    Reactions of D atoms with OCS were studied by 193-nm pulsed laser photolysis of DBr as a nearly monoenergetic D-atom source. Nascent OD(X/sup 2/II) and SD(X/sup 2/II) rotational, vibrational, spin-orbit, and ..lambda..-doublet populations were obtained under single-collision bulk conditions at 300 K. The SD channel is favored energetically (..delta.. H = -43 +/- 13 and 230 +/- 13 kJ mol/sup -1/ for the SD and OD channels, respectively) and is the dominant pathway ((SD)/(OD) = 5 +/- 2). Nascent OD(X/sup 2/II) products were also obtained from a precursor geometry limited (PGL) reaction by using the weakly bound van der Waals complex SCO-DBr. The OD(X/sup 2/II) rotational distributions are the same for both bulk and PGL conditions and can be reproduced by using a statistical model. Due to experimental difficulties, SD(X/sup 2/II) distributions could not be obtained under PGL conditions. The SD(X/sup 2/II) distribution obtained under bulk conditions is very nonstatistical, suggesting that this species is not formed via a long-lived DSCO intermediate complex in which vibrational energy is randomized.

  4. Chemical profile of the secondary metabolites produced by a deep-sea sediment-derived fungus Penicillium commune SD-118

    NASA Astrophysics Data System (ADS)

    Shang, Zhuo; Li, Xiaoming; Meng, Li; Li, Chunshun; Gao, Shushan; Huang, Caiguo; Wang, Bingui

    2012-03-01

    Bioassay-guided fractionation of the crude extract from Penicillium commune SD-118, a fungus obtained from a deep-sea sediment sample, resulted in the isolation of a known antibacterial compound, xanthocillin X ( 1), and 14 other known compounds comprising three steroids ( 2-4), two ceramides ( 5 and 6), six aromatic compounds ( 7-12), and three alkaloids ( 13-15). Xanthocillin X ( 1) was isolated for the first time from a marine fungus. In the bioassay, xanthocillin X ( 1) displayed remarkable antimicrobial activity against Staphylococcus aureus and Escherichia coli, and significant cytotoxicity against MCF-7, HepG2, H460, Hela, Du145, and MDA-MB-231 cell lines. Meleagrin ( 15) exhibited cytotoxicity against HepG2, Hela, Du145, and MDA-MB-231 cell lines. This is the first report of the cytotoxicity of xanthocillin X ( 1).

  5. Analysis of Genes for Succinoyl Trehalose Lipid Production and Increasing Production in Rhodococcus sp. Strain SD-74

    PubMed Central

    Inaba, Tomohiro; Tokumoto, Yuta; Miyazaki, Yusuke; Inoue, Naoyuki; Maseda, Hideaki; Nakajima-Kambe, Toshiaki; Uchiyama, Hiroo

    2013-01-01

    Succinoyl trehalose lipids (STLs) are promising glycolipid biosurfactants produced from n-alkanes that are secreted by Rhodococcus species bacteria. These compounds not only exhibit unique interfacial properties but also demonstrate versatile biochemical actions. In this study, three novel types of genes involved in the biosynthesis of STLs, including a putative acyl coenzyme A (acyl-CoA) transferase (tlsA), fructose-bisphosphate aldolase (fda), and alkane monooxygenase (alkB), were identified. The predicted functions of these genes indicate that alkane metabolism, sugar synthesis, and the addition of acyl groups are important for the biosynthesis of STLs. Based on these results, we propose a biosynthesis pathway for STLs from alkanes in Rhodococcus sp. strain SD-74. By overexpressing tlsA, we achieved a 2-fold increase in the production of STLs. This study advances our understanding of bacterial glycolipid production in Rhodococcus species. PMID:24038682

  6. Toxic Effects of Tetrabromobisphenol A on Thyroid Hormones in SD Rats and the Derived-reference Dose.

    PubMed

    Yang, Yan; Ni, Wei Wei; Yu, Lin; Cai, Ze; Yu, Yun Jiang

    2016-04-01

    The present study determined the thyroid hormone interference of tetrabromobisphenol A (TBBPA) in Sprague-Dawley (SD) rats, and the derived-reference dose (RfD) of different endpoint effects on mammals based on experimental results and data collection. Based on repeated exposure toxicity tests on mammals and extensive research, the present study used BMDS240 Software to derive a benchmark dose, and analyzed the accuracy and uncertainty, and similarity with other studies. Test results on triiodothyronine (T3), thyroxine (T4), and thyroid stimulating hormone (TSH) demonstrated that all the indicators presented a non-monotonous dose-effect relationship clearly, except TSH in male rats exposed to 0-1000 mg/kg BW per day. Therefore, RfDs were derived from different critical effects. In summary, RfD for mammals in the present study was found to be 0.6 mg/kg per day. PMID:27241741

  7. Continuous imaging of the blood vessels in tumor mouse dorsal skin window chamber model by using SD-OCT

    NASA Astrophysics Data System (ADS)

    Peng, Xiao; Yang, Shaozhuang; Yu, Bin; Wang, Qi; Lin, Danying; Gao, Jian; Zhang, Peiqi; Ma, Yiqun; Qu, Junle; Niu, Hanben

    2016-03-01

    Optical Coherence Tomography (OCT) has been widely applied into microstructure imaging of tissues or blood vessels with a series of advantages, including non-destructiveness, real-time imaging, high resolution and high sensitivity. In this study, a Spectral Domain OCT (SD-OCT) system with higher sensitivity and signal-to-noise ratio (SNR) was built up, which was used to observe the blood vessel distribution and blood flow in the dorsal skin window chamber of the nude mouse tumor model. In order to obtain comparable data, the distribution images of blood vessels were collected from the same mouse before and after tumor injection. In conclusion, in vivo blood vessel distribution images of the tumor mouse model have been continuously obtained during around two weeks.

  8. NLTE spectral analysis of the sdOB primary of the eclipsing binary system LB 3459 (AA Dor)

    NASA Astrophysics Data System (ADS)

    Rauch, T.

    2000-04-01

    We present a spectral analysis of the sdOB primary star of the binary system LB 3459 based on high-resolution high-S/N optical and UV spectra. The metal abundances are determined by means of state-of-the-art NLTE model atmospheres. We determined Teffw42 and log gw{5.2} within very small error limits. The He (1/125 solar), C (1/265), N (1/33), O (1/12), and Si (1/5) abundances appear strongly depleted while that of Fe and Ni are roughly solar and Mg is strongly enriched by a factor of 6. The spectroscopic distance to LB 3459 is d = 396 pc. The mass of the primary component of LB 3459 is 0.330 M_sun derived from comparisons with theoretical models for sdO stars in the log T_eff - \\log g plane. The mass of the secondary is then 0.066 M_sun derived from the mass function. There remains some disagreement between the radius derived from log g and the above mass, and that derived from analysis of the radial-velocity curve and the eclipse curves. LB 3459 is a close binary system which had experienced a common envelope (CE) phase during its evolution. It fits in the ``low mass case B'' scenario of Iben & Livio (1993) and the secondary is a brown dwarf. The spectroscopically determined rotational velocity of the primary is v_rot = 34 ± 10 km* sec-1. Thus even bound rotation (v_rot = 45.7 km* sec-1) cannot be ruled out. Based on observations collected at the European Southern Observatory, La Silla, Chile (proposals 55.D-0319, 56.C-0165) and on data retrieved from the International Ultraviolet Explorer (IUE) Final Archive.

  9. Quantitatively evaluating detoxification of the hepatotoxic microcystin-LR through the glutathione (GSH) pathway in SD rats.

    PubMed

    Guo, Xiaochun; Chen, Liang; Chen, Jun; Xie, Ping; Li, Shangchun; He, Jun; Li, Wei; Fan, Huihui; Yu, Dezhao; Zeng, Cheng

    2015-12-01

    Glutathione (GSH) plays crucial roles in antioxidant defense and detoxification metabolism of microcystin-LR (MC-LR). However, the detoxification process of MC-LR in mammals remains largely unknown. This paper, for the first time, quantitatively analyzes MC-LR and its GSH pathway metabolites (MC-LR-GSH and MC-LR-Cys) in the liver of Sprague-Dawley (SD) rat after MC-LR exposure. Rats received intraperitoneal (i.p.) injection of 0.25 and 0.5 lethal dose 50 (LD50) of MC-LR with or without pretreatment of buthionine-(S,R)-sulfoximine (BSO), an inhibitor of GSH synthesis. The contents of MC-LR-GSH were relatively low during the experiment; however, the ratio of MC-LR-Cys to MC-LR reached as high as 6.65 in 0.5 LD50 group. These results demonstrated that MC-LR-GSH could be converted to MC-LR-Cys efficiently, and this metabolic rule was in agreement with the data of aquatic animals previously reported. MC-LR contents were much higher in BSO + MC-LR-treated groups than in the single MC-LR-treated groups. Moreover, the ratio of MC-LR-Cys to MC-LR decreased significantly after BSO pretreatment, suggesting that the depletion of GSH induced by BSO reduced the detoxification of MCs. Moreover, MC-LR remarkably induced liver damage, and the effects were more pronounced in BSO pretreatment groups. In conclusion, this study verifies the role of GSH in the detoxification of MC-LR and furthers our understanding of the biochemical mechanism for SD rats to counteract toxic cyanobacteria. PMID:26490924

  10. Effects of Methane-Rich Saline on the Capability of One-Time Exhaustive Exercise in Male SD Rats

    PubMed Central

    Xin, Lei; Sun, Xuejun; Lou, Shujie

    2016-01-01

    Purpose To explore the effects of methane-rich saline (CH4 saline) on the capability of one-time exhaustive exercise in male SD rats. Methods Thirty rats were equally divided into to three groups at random: control group (C), placebo group (P) and methane saline group (M). Rats in M group underwent intraperitoneal injection of CH4 saline, and the other two groups simultaneously underwent intraperitoneal injection of normal saline. Then, the exercise capability of rats was tested through one-time exhaustive treadmill exercise except C group. Exercise time and body weight were recorded before and after one-time exhaustive exercise. After exhaustive exercise, the blood and gastrocnemius samples were collected from all rats to detect biochemical parameters in different methods. Results It was found that the treadmill running time was significantly longer in rats treated with CH4 saline. At the same time, CH4 saline reduced the elevation of LD and UN in blood caused by one-time exhaustive exercise. The low level of blood glucose induced by exhaustive exercise was also normalized by CH4 saline. Also CH4 saline lowered the level of CK in plasma. Furthermore, this research indicated that CH4 saline markedly increased the volume of T-AOC in plasma and alleviated the peak of TNF-α in both plasma and gastrocnemius. From H&E staining, CH4 saline effectively improved exercise-induced structural damage in gastrocnemius. Conclusions CH4 saline could enhance exercise capacity in male SD rats through increase of glucose aerobic oxidation, improvement of metabolic clearance and decrease of exhaustive exercise-induced gastrocnemius injury. PMID:26942576

  11. Ion beam synthesis of 3C-(Si1-xC1-y)Gex+y solid solutions

    NASA Astrophysics Data System (ADS)

    Weih, P.; Stauden, Th.; Ecke, G.; Shokhovets, S.; Zgheib, Ch.; Voelskow, M.; Skorupa, W.; Ambacher, O.; Pezoldt, J.

    2005-03-01

    In the present study cubic 3C-(Si1-xC1-y)Gex+y solid solutions were created by using ion beam synthesis. 3C-SiC thin layers grown on on-axis Si (111) substrates by Molecular Beam Epitaxy were implanted with Ge in order to incorporate Ge atoms in the Silicon Carbide lattice. Two series of experiments were carried out. The implantation energy was chosen to be 140 keV and 200 keV and the implantation dose 1 × 1017 cm-2 and 4.7 × 1016 cm-2 respectively. The samples were annealed under rapid thermal annealing conditions in the temperature range between 800 °C and 1300 °C. X-ray diffraction measurements indicate an enlargement of the lattice constant. The observed higher absorption in the implanted layers could be a sign of a band gap reduction as a consequence of Ge incorporation.

  12. Compositional dependence of optical transition energies in highly mismatched Zn1-xCdxTe1-yOy alloys

    NASA Astrophysics Data System (ADS)

    Tanaka, Tooru; Mizoguchi, Kosuke; Terasawa, Toshiki; Okano, Yuuki; Saito, Katsuhiko; Guo, Qixin; Nishio, Mitsuhiro; Yu, Kin Man; Walukiewicz, Wladek

    2016-02-01

    Highly mismatched Zn1-xCdxTe1-yOy layers with a wide range of Cd and O compositions of 0-0.7 and 0.005-0.02, respectively, were grown by molecular beam epitaxy for the application of intermediate band solar cells. The electron transition energies from the valence band (VB) to E- and E+ bands decreased with increasing Cd content. The variation of the transition energies was consistent with the theoretical calculation based on the band anticrossing model. The magnitude of the optical absorption due to electron transitions from the VB to E- band was strongly dependent on the Cd content because of the changing character of the E- band.

  13. Quaternary Bismide Alloy ByGa1-yAs1-xBix Lattice Matched to GaAs

    SciTech Connect

    Deaton, D. A.; Ptak, A. J.; Alberi, K.; Mascarenhas, A.

    2012-07-15

    We report on the lattice matched quaternary alloy, B{sub y}Ga{sub 1-y}As{sub 1-x}Bi{sub x} grown by molecular beam epitaxy at conditions conducive to bismuth incorporation. Incorporating a smaller atom (boron) along with the larger atom (bismuth) allows for a reduction of the epi-layer strain and lattice matching to GaAs for compositions of Bi:B{approx_equal}1.3:1. The addition of boron flux does not significantly affect the bismuth incorporation and no change in the band gap energy is observed with increasing boron content. However, excess, non-substitutional boron is incorporated which leads to an increase in hole density, as well as an increase in the density of shallow in-gap states as observed by the loss of localization of photo-excited excitons.

  14. Nonlinear structure-composition relationships in the Ge1-ySny/Si(100) (y<0.15) system

    DOE PAGESBeta

    Beeler, R.; Roucka, R.; Chizmeshya, A. V. G.; Kouvetakis, J.; Menéndez, J.

    2011-07-26

    The compositional dependence of the cubic lattice parameter in Ge1-ySny alloys has been revisited. Large 1000-atom supercell ab initio simulations confirm earlier theoretical predictions that indicate a positive quadratic deviation from Vegard's law, albeit with a somewhat smaller bowing coefficient, θ = 0.047 Å, than found from 64-atom cell simulations (θ = 0.063 Å). On the other hand, measurements from an extensive set of alloy samples with compositions y < 0.15 reveal a negative deviation from Vegard's law. The discrepancy with earlier experimental data, which supported the theoretical results, is traced back to an unexpected compositional dependence of the residualmore » strain after growth on Si substrates. The experimental bowing parameter for the relaxed lattice constant of the alloys is found to be θ = -0.066 Å. Possible reasons for the disagreement between theory and experiment are discussed in detail.« less

  15. Structures and magnetic properties of Tm1- y Y y Mn1- x Co x O3

    NASA Astrophysics Data System (ADS)

    Tanaka, Toshiyuki; Kumagai, Akira; Amakai, Yusuke; Momono, Naoki; Murayama, Shigeyuki; Takano, Hideaki

    2013-08-01

    The structure and magnetic properties of Tm1- y Y y Mn1- x Co x O3 with 0 ≦ x ≦ 0.5 and 0 ≦ y ≦ 0.3 were investigated by X-ray diffraction, specific heat and magnetization measurements. Thulium manganite TmMnO3 prepared by solid-state synthesis at ambient pressure is hexagonal and antiferromagnetic with a Nèel temperature T N of 86 K. The substitution of Y for Tm in TmMnO3 does not greatly affect the fundamental hexagonal structure. The magnetization and specific heat measurement results for Tm1- y Y y MnO3 can be qualitatively explained in terms of the dilution effect of Tm by Y. On the other hand, the structure of TmMn1- x Co x O3 changes gradually from hexagonal to orthorhombic with the substitution of Co for Mn; hexagonal and orthorhombic phases coexist in samples for x ≦ 0.3 whereas TmMn0.6Co0.4O3 is almost a single orthorhombic phase. The magnetization of TmMn0.6Co0.4O3 in a field of 250 Oe increases rapidly at about 60K with decreasing temperature. The difference between zero-field-cooled (ZFC) and field-cooled (FC) magnetizations increases remarkably at about 60 K. Moreover, the temperature dependences of the ZFC and the FC magnetizations exhibit peaks at about 40 and 30K, respectively. Thus, TmMn1- x Co x O3 exhibits complex magnetic properties.

  16. High antimony content GaAs1-zNz-GaAs1-ySby type-II ``W'' structure for long wavelength emission

    NASA Astrophysics Data System (ADS)

    Rathi, M. K.; Khandekar, A. A.; Song, Xueyan; Babcock, S. E.; Mawst, L. J.; Kuech, T. F.

    2009-09-01

    GaAs1-zNz-GaAs1-ySby type-II "W" structures were studied for long wavelength (1300-1600 nm) applications. These structures were grown on a GaAs substrate using metal-organic vapor phase epitaxy. The antimony and nitrogen compositions in the pseudomorphic GaAs1-ySby and GaAs1-zNz were estimated by separately growing GaAs1-ySby-GaAs and GaAs1-zNz-GaAs strained superlattices. X-ray studies indicate that a maximum of y =0.37 antimony can be incorporated in the pseudomorphic GaAs1-ySby film grown using triethyl gallium (TEGa), trimethyl antimony (TMSb) and arsine (AsH3) at the growth temperatures employed. A postgrowth anneal was used to improve the emission intensity but leads to shifts in the emission wavelength. An emission wavelength as long as 1.47 μm was realized using a GaAs1-zNz-GaAs1-ySby-GaAs1-zNz structure.

  17. Hybridization and suppression of the superconductivity in CeFeAsO1-y. Pressure and temperature dependences of the electronic structure

    SciTech Connect

    Yamaoka, Hitoshi; Jarrige, Ignace; Ikeda-Ohno, Atsushi; Tsutsui, Satoshi; Lin, Jung-Fu; Takeshita, Nao; Miyazawa, Kiichi; Iyo, Akira; Kito, Hijiri; Eisaki, Hiroshi; Hiraoka, Nozomu; Ishii, Hirofumi; Tsuei, Ku-Ding

    2010-09-23

    Pressure and temperature dependence of the electronic structure of superconducting (SC) CeFeAsO1-y and non-SC CeFeAsO1-y have been investigated using two complementary hard x-ray spectroscopic probes at the Ce L3 edge, partial fluorescence yield x-ray absorption spectroscopy and resonant x-ray emission spectroscopy. With increasing pressure, the ratio between the intensity of the peak related to the f0 (Ce4+ ) state and that of the f1 (Ce3+ ) state, I(f0)/I(f1 ), is found to increase continuously for both compounds, indicating a continuous increase in the Ce valence. The valence of non-SC CeFeAsO1-y is found to be slightly higher than that of SC CeFeAsO1-y in the entire pressure and temperature ranges of this study. The valence of CeFeAsO1-y around 6 GPa, where the superconductivity breaks down, is estimated to be ~3.0 , but no change in the valence is observed upon cooling. The dependence of the interatomic distances on the concentration of oxygen vacancies is studied via extended absorption fine structure spectroscopy.

  18. Molecular beam epitaxial growth and optical properties of lattice-matched MgxZn1-xSeyTe1-y alloys on InP substrates

    NASA Astrophysics Data System (ADS)

    Naniwae, Koichi; Iwata, Hiroshi; Yashiki, Kenichiro

    1999-06-01

    Molecular beam epitaxial growth and the optical properties of lattice-matched MgxZn1-xSeyTe1-y alloys on InP were investigated. Two-dimensional growth and high crystalline quality were achieved by forming an InP buffer layer and a Zn0.48Cd0.52Se buffer layer before the MgxZn1-xSeyTe1-y layer growth. The band-gap energy (Eg) of the MgxZn1-xSeyTe1-y films, measured by optical-reflection measurements, increased with the Mg content and is expressed by the quadratic equation Eg=0.90x2+0.83x+2.37. We found that the Stokes shifts of MgxZn1-xSeyTe1-y quaternary alloys, which seemed to originate from deep trap levels related to Te clusters, were larger than those of ZnSeTe ternary alloys. The refractive index of MgxZn1-xSeyTe1-y at a wavelength of 600 nm decreased as the Mg content rose, as expressed by the linear equation n600(x)=-1.09x+2.99.

  19. SD-208, a Novel Protein Kinase D Inhibitor, Blocks Prostate Cancer Cell Proliferation and Tumor Growth In Vivo by Inducing G2/M Cell Cycle Arrest

    PubMed Central

    Tandon, Manuj; Salamoun, Joseph M.; Carder, Evan J.; Farber, Elisa; Xu, Shuping; Deng, Fan; Tang, Hua; Wipf, Peter; Wang, Q. Jane

    2015-01-01

    Protein kinase D (PKD) has been implicated in many aspects of tumorigenesis and progression, and is an emerging molecular target for the development of anticancer therapy. Despite recent advancement in the development of potent and selective PKD small molecule inhibitors, the availability of in vivo active PKD inhibitors remains sparse. In this study, we describe the discovery of a novel PKD small molecule inhibitor, SD-208, from a targeted kinase inhibitor library screen, and the synthesis of a series of analogs to probe the structure-activity relationship (SAR) vs. PKD1. SD-208 displayed a narrow SAR profile, was an ATP-competitive pan-PKD inhibitor with low nanomolar potency and was cell active. Targeted inhibition of PKD by SD-208 resulted in potent inhibition of cell proliferation, an effect that could be reversed by overexpressed PKD1 or PKD3. SD-208 also blocked prostate cancer cell survival and invasion, and arrested cells in the G2/M phase of the cell cycle. Mechanistically, SD-208-induced G2/M arrest was accompanied by an increase in levels of p21 in DU145 and PC3 cells as well as elevated phosphorylation of Cdc2 and Cdc25C in DU145 cells. Most importantly, SD-208 given orally for 24 days significantly abrogated the growth of PC3 subcutaneous tumor xenografts in nude mice, which was accompanied by reduced proliferation and increased apoptosis and decreased expression of PKD biomarkers including survivin and Bcl-xL. Our study has identified SD-208 as a novel efficacious PKD small molecule inhibitor, demonstrating the therapeutic potential of targeted inhibition of PKD for prostate cancer treatment. PMID:25747583

  20. Chalcogen (O2, S, Se, Te) atmosphere annealing induced bulk superconductivity in Fe1+yTe1-xSex single crystal

    NASA Astrophysics Data System (ADS)

    Sun, Y.; Tsuchiya, Y.; Yamada, T.; Taen, T.; Pyon, S.; Shi, Z. X.; Tamegai, T.

    2014-09-01

    We reported a detailed study of Fe1+yTe0.6Se0.4 single crystals annealed in the atmosphere of chalcogens (O2, S, Se, Te). After annealing with appropriate amount of chalcogens, Fe1+yTe0.6Se0.4 single crystals show Tc higher than 14 K with a sharp transition width ∼1 K. Critical current density Jc for the annealed crystals reach a very high value ∼2-4 × 105 A/cm2 under zero field, and is also robust under applied field at low temperatures. Magneto-optical imaging reveal that the Jc is homogeneously distributed in the annealed crystals and isotropic in the ab-plane. Our results show that annealing in the atmosphere of chalcogens can successfully induce bulk superconductivity in Fe1+yTe0.6Se0.4.

  1. Oliver E. Buckley Condensed Matter Prize Lecture: S-d Exchange, Spin Accumulation, And The Roots Of Spintronics

    NASA Astrophysics Data System (ADS)

    Berger, Luc

    2013-03-01

    The success of spintronics in metals such as nickel, cobalt, Ni-Fe and Ni-Co is based on the existence of high-mobility spin-up 4s electrons at the Fermi level, which carry most of the current. The spin-up Fermi level is located above the top of the 3d band. This basic fact, first recognized by Mott in 1936, was confirmed by the Hall-effect measurements of Pugh et al. (1950-1965), and by data of deviation from Matthiessen's rule by Campbell, Fert and Jaoul (1967-1977). In order to explain giant magnetoresistance and the existence of the spin-transfer torque, an interaction is needed which couples 4s conduction electrons to magnetic 3d electrons. This is the s-d exchange interaction, introduced by Vonsovskii in 1946 and Zener in 1951. Theories of Gilbert damping, based on s-d exchange, were soon developed (Turov (1955), Mitchell (1957)). But a serious problem was caused by the existence of a momentum gap between spin-up and spin-down Fermi surfaces, which prevents spin switching from happening at low T. The problem can be solved if local defects exist which act as extra sources of momentum. One such source is spin-flip scattering (Turov (1961), Heinrich, Freitova and Kambersky (1967)). A second one is the presence of an interface (Slonczewski (1996), Berger (1996)). Spin accumulation is another concept of importance to spintronics. It represents an imbalance between spin-up and spin-down Fermi levels. Introduced by Aronov in 1976, it was developed by Johnson and Silsbee (1985-1993) and by Valet and Fert (1993). It is the hidden agent through which the current ``pumps'' energy into many spintronics devices. In semiconductor lasers, the same role is played by the difference between conduction-band and valence-band Fermi levels. A momentum gap problem also exists in lasers made of indirect-gap semiconductors, and it is solved similarly.

  2. Paleointensity estimates derived from non-SD recording materials: Testing the IZZI technique on MD slag and a new bootstrap procedure

    NASA Astrophysics Data System (ADS)

    Shaar, R.; Ron, H.; Tauxe, L.; Kessel, R.; Agnon, A.

    2011-12-01

    Experimental techniques to determine paleomagnetic field intensity are based on a theoretical framework that is valid only for single-domain (SD) ferromagnetic particles. Yet, most of the available materials exhibit distinctly non-SD properties. Hence, designing a robust paleointensity methodology for non-SD is a fundamental challenge in paleomagnetism. Here we test the IZZI Thellier absolute paleointensity technique on slag material that has properties of small MD. The test has two purposes: 1) to describe the characteristic non-SD patterns occurring in Arai plots, and 2) to identify the optimal approach in interpreting non-SD behavior. We produced 4 synthetic re-melted slag samples with identical magneto-mineralogical properties under field intensities of 20, 40, 60 and 80 μT. We ran three batches of IZZI paleointensity experiments on 10 specimens per samples. The IZZI experiments were designed to identify the dependency of the results on the ratio and the angle between the field used in the paleointensity experiment (BTRM) and the field in which the NRM was acquired (BNRM). The results demonstrate different types of Arai plots, systematically dependent on the angle and the proportion between BTRM and BNRM. Straight-line Arai plots occur when the two fields are parallel and equal, and seem to always give the 'true' slope. Convex curves occur when BTRM is parallel and significantly stronger than BNRM. Concave curves occur in all the other cases and yield two end-case slopes that are always different from the 'true' slope. The zigzags of the Arai plot increase with the proportion between BTRM and BNRM, and as the angle between BTRM and BNRM approaches 90°. We test the accuracy of the commonly used data analysis approach of best fitting line through a chosen segment of the Arai plot. We conclude that best fitting line in curved plots cannot provide robust paleointensity estimates. However, the two 'end-case' slopes in concave curves can provide adequate

  3. A population of serumdeprivation-induced bone marrow stem cells (SD-BMSC) expresses marker typical for embryonic and neural stem cells

    SciTech Connect

    Sauerzweig, Steven Munsch, Thomas; Lessmann, Volkmar; Reymann, Klaus G.; Braun, Holger

    2009-01-01

    The bone marrow represents an easy accessible source of adult stem cells suitable for various cell based therapies. Several studies in recent years suggested the existence of pluripotent stem cells within bone marrow stem cells (BMSC) expressing marker proteins of both embryonic and tissue committed stem cells. These subpopulations were referred to as MAPC, MIAMI and VSEL-cells. Here we describe SD-BMSC (serumdeprivation-induced BMSC) which are induced as a distinct subpopulation after complete serumdeprivation. SD-BMSC are generated from small-sized nestin-positive BMSC (S-BMSC) organized as round-shaped cells in the top layer of BMSC-cultures. The generation of SD-BMSC is caused by a selective proliferation of S-BMSC and accompanied by changes in both morphology and gene expression. SD-BMSC up-regulate not only markers typical for neural stem cells like nestin and GFAP, but also proteins characteristic for embryonic cells like Oct4 and SOX2. We hypothesize, that SD-BMSC like MAPC, MIAMI and VSEL-cells represent derivatives from a single pluripotent stem cell fraction within BMSC exhibiting characteristics of embryonic and tissue committed stem cells. The complete removal of serum might offer a simple way to specifically enrich this fraction of pluripotent embryonic like stem cells in BMSC cultures.

  4. An Asteroseismological Analysis of the Short-Period Pulsating sdB Star EC 05217-3914

    NASA Astrophysics Data System (ADS)

    Billères, M.; Fontaine, G.

    2005-07-01

    We present the results of a detailed asteroseimological analysis of the southern hemisphere sdB pulsator EC 05217-3914. This analysis rests on our gathering of high S/N ratio observations at the NTT using the SUSI2 camera. Some 37 h of data were obtained over a 5 night run. We uncovered several frequency components in the period range 129-218 s, several of which form multiplets with equally spaced components. The latter are best explained in terms of rotational splitting in a star with a rotation period of 13.1 h. Excluding the rotationally-split components, we identified 5 independent pulsation modes with which to play the game of asteroseismology. Using an efficient period-matching code we explored the parameter space and found an excellent fit to the observed periods. We present the results of this exercise: our preliminary identification of the pulsation modes in EC 05217-3914 and the determination of its fundamental parameters through asteroseismology.

  5. A planet orbiting an sdB star and an M dwarf in 2M 1938+4603

    NASA Astrophysics Data System (ADS)

    Blokesz, Adam; Baran, Andrzej; Zola, Stanislaw

    2015-09-01

    We present a preliminary analysis of the 2M 1938+4603 star. It is an eclipsing binary system consisting of a primary sdB component and a secondary M dwarf. The photometric data are dominated by mutual eclipses and a very strong reflection effect. The primary has a fairly rich pulsation spectrum which can be used to study its interior. On the other hand, the pulsations affect the binary trend and vice versa what makes the analysis very difficult. Therefore, we attempted at proper modeling of the light variation due to eclipses and reflection and their removal from the data so it does not affect the Fourier analysis of stellar pulsations. We focus on mid-times of over 16 000 primary and secondary minima, which were used to verify stability of the orbital period. The O-C diagram indicates possible parabolic and sinusoidal variations, commonly explained by period changes caused by evolution and a presence of a third body, respectively.

  6. Improving the Significance of MM/SD Risk Analysis by Application of the SRL Ballistic Limit Equation

    NASA Astrophysics Data System (ADS)

    Schafer, Frank; Putzar, Robin; Ryan, Shannon; Lambert, Michel

    2009-03-01

    In this paper, a new ballistic limit equation (BLE) for satellite equipment placed behind satellite structure walls is presented. Application of this equation in micrometeoroid and space debris (MM/SD) risk analysis (RA) tools for satellites can lead to a more realistic quantitative assessment of the actual failure risk of satellite equipment from hypervelocity impacts (HVI) and hence, of the failure risk of a satellite. This is because in contrast to the BLEs that are currently in use in RA tools, in the new equation the intrinsic shielding capabilities of the satellite equipment are considered explicitly.The BLE has been developed for application to configurations consisting of a Whipple shield or a honeycomb sandwich panel placed in front of a backwall. It considers explicitly the thickness, material and spacing of each of the three involved plates. The backwall represents the cover plate or the external wall of spacecraft equipment that is placed behind the spacecraft's structure wall. The BLE has been experimentally calibrated to the most common spacecraft equipment: fuel and heat pipes, pressure vessels, electronics boxes, harness, and batteries. Further, suitable failure criteria have been defined for each equipment type. The critical projectile masses calculated with the new BLE for satellite equipment placed behind satellite structure walls are considerably larger than the critical projectile masses calculated for the standalone structure wall of the satellite.

  7. Successful prevention of post-transfusion Rh alloimmunization by intravenous Rho (D) immune globulin (WinRho SD).

    PubMed

    Anderson, B; Shad, A T; Gootenberg, J E; Sandler, S G

    1999-03-01

    Alloimmunization to the D blood group antigen following the transfusion of D-positive red blood cells to a D-negative recipient may be prevented in most persons by a prompt and adequate dose of Rho (D) immune globulin (RhIG). Until recently, the only RhIG approved by the US Food and Drug Administration (FDA) for this indication required intramuscular injection, an inconvenient and painful route for the relatively large volume that may be required. We describe the successful prevention of Rh alloimmunization following the unintentional transfusion of D-positive red blood cells to a D-negative infant by the intravenous infusion of WinRho SD, a new RhIG that is FDA-approved for prevention of post-transfusion Rh alloimmunization by intravenous administration. We believe that this more convenient and less painful approach should be the treatment of choice for preventing Rh alloimmunization following the transfusion of D-positive red cells to a D-negative recipient. PMID:10072121

  8. Optically deviated focusing method based high-speed SD-OCT for in vivo retinal clinical applications

    NASA Astrophysics Data System (ADS)

    Wijesinghe, Ruchire Eranga; Park, Kibeom; Kim, Pilun; Oh, Jaeryung; Kim, Seong-Woo; Kim, Kwangtae; Kim, Beop-Min; Jeon, Mansik; Kim, Jeehyun

    2016-04-01

    The aim of this study is to provide accurately focused, high-resolution in vivo human retinal depth images using an optically deviated focusing method with spectral-domain optical coherence tomography (SD-OCT) system. The proposed method was applied to increase the retinal diagnosing speed of patients with various values of retinal distances (i.e., the distance between the crystalline eye lens and the retina). The increased diagnosing speed was facilitated through an optical modification in the OCT sample arm configuration. Moreover, the optical path length matching process was compensated using the proposed optically deviated focusing method. The developed system was mounted on a bench-top cradle to overcome the motion artifacts. Further, we demonstrated the capability of the system by carrying out in vivo retinal imaging experiments. The clinical trials confirmed that the system was effective in diagnosing normal and abnormal retinal layers as several retinal abnormalities were identified using non-averaged single-shot OCT images, which demonstrate the feasibility of the method for clinical applications.

  9. Mode identification based on time-series spectrophotometry for the bright rapid sdB pulsator EC 01541-1409

    NASA Astrophysics Data System (ADS)

    Randall, S. K.; Fontaine, G.; Geier, S.; Van Grootel, V.; Brassard, P.

    2014-03-01

    We present an analysis of time-resolved spectrophotometry gathered with FORS/VLT for the rapidly pulsating hot B subdwarf EC 01541-1409 with the aim of identifying the degree index ℓ of the larger amplitude modes. This mode identification can be extremely useful in detailed searches for viable asteroseismic models in parameter space, and can be crucial for testing the validity of a solution a posteriori. To achieve it, we exploit the ℓ-dependence of the monochromatic amplitude, phase, and velocity-to-amplitude ratio of a mode as a function of wavelength. We use the ℓ-sensitive phase lag between the flux perturbation and the radial velocity as an additional diagnostic tool. On this basis, we are able to unambiguously identify the dominant 140.5 s pulsation of our target as a radial mode, and the second-highest amplitude periodicity at 145.8 s as an ℓ = 2 mode. We further exploit the exceptionally high-sensitivity data that we gathered for the dominant mode to infer modal properties that are usually quite difficult to estimate in sdB pulsators, namely the physical values of the dimensionless radius, temperature, and surface gravity perturbations. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere, Chile (proposal ID 087.D-0047).Appendix A is available in electronic form at http://www.aanda.org

  10. Incorporation of learned shape priors into a graph-theoretic approach with application to the 3D segmentation of intraretinal surfaces in SD-OCT volumes of mice

    NASA Astrophysics Data System (ADS)

    Antony, Bhavna J.; Song, Qi; Abràmoff, Michael D.; Sohn, Eliott; Wu, Xiaodong; Garvin, Mona K.

    2014-03-01

    Spectral-domain optical coherence tomography (SD-OCT) finds widespread use clinically for the detection and management of ocular diseases. This non-invasive imaging modality has also begun to find frequent use in research studies involving animals such as mice. Numerous approaches have been proposed for the segmentation of retinal surfaces in SD-OCT images obtained from human subjects; however, the segmentation of retinal surfaces in mice scans is not as well-studied. In this work, we describe a graph-theoretic segmentation approach for the simultaneous segmentation of 10 retinal surfaces in SD-OCT scans of mice that incorporates learned shape priors. We compared the method to a baseline approach that did not incorporate learned shape priors and observed that the overall unsigned border position errors reduced from 3.58 +/- 1.33 μm to 3.20 +/- 0.56 μm.

  11. Control of grain protein contents through SEMIDWARF1 mutant alleles: sd1 increases the grain protein content in Dee-geo-woo-gen but not in Reimei.

    PubMed

    Terao, Tomio; Hirose, Tatsuro

    2015-06-01

    A new possibility for genetic control of the protein content of rice grains was suggested by the allele differences of the SEMIDWARF1 (SD1) mutation. Two quantitative trait loci-qPROT1 and qPROT12-were found on chromosomes 1 and 12, respectively, using backcrossed inbred lines of Sasanishiki/Habataki//Sasanishiki///Sasanishiki. One of them, qPROT1, increased almost all grain proteins instead of only certain proteins in the recessive Habataki allele. Fine mapping of qPROT1 revealed that two gene candidates-Os01g0883800 and Os01g0883900-were included in this region. Os01g0883800 encoded Gibberellin 20 oxidase 2 as well as SD1, the dwarf gene used in the so-called 'Green Revolution'. Mutant analyses as well as sequencing analysis using the semi-dwarf mutant cultivars Dee-geo-woo-gen and Calrose 76 revealed that the sd1 mutant showed significantly higher grain protein contents than their corresponding wild-type cultivars, strongly suggesting that the high protein contents were caused by sd1 mutation. However, the sd1 mutant Reimei did not have high grain protein contents. It is possible to control the grain protein content and column length separately by selecting for sd1 alleles. From this finding, the genetic control of grain protein content, as well as the column length of rice cultivars, might be possible. This ability might be useful to improve rice nutrition, particularly in areas where the introduction of semi-dwarf cultivars is not advanced. PMID:25492221

  12. Density functional theory calculations of the turbostratically disordered compound [(SnSe)1+y]m(VSe2)n

    DOE PAGESBeta

    Rudin, Sven P.; Johnson, David C.

    2015-04-30

    Among composite materials that layer constituent substances of nanoscale thicknesses, [(SnSe)1+y ]m(VSe2)n emerges as an example where the constituents retain incommensurate lattice structures. Perpendicular to the stacking direction, the system exhibits random translations and random rotations on average, i.e., turbostratic disorder, with local regions showing twelvefold diffraction patterns. Earlier theoretical work on these structures showed that combining density functional theory with an empirical treatment of the van der Waals interaction gave structural parameters in good agreement with experiment, but no attempt was made to examine the relative orientations. Here we approximate the extended system with one extended constituent and onemore » finite constituent, which allows the treatment of all relative orientations on equal footing. Furthermore, the calculations show how the twelvefold periodicity follows from how the ions of the SnSe layer lock in with favored positions relative to the VSe2 layer, and the associated energy scale supports arguments for the overall turbostratic disorder.« less

  13. Electronic structures and the estimated Curie temperatures of (Ga1-yIny)1-xMnxAs

    NASA Astrophysics Data System (ADS)

    Miura, K.; Iwasawa, M.; Imanaga, S.; Ami, T.

    2003-12-01

    The electronic structures of (Ga1-yIny)1-xMnxAs have been investigated using the Korringa, Kohn and Rostoker (KKR) method with the coherent potential approximation (CPA). The estimated Curie temperature (TC) of Ga1-xMnxAs is higher than that of (Ga0.5In0.5)1-xMnxAs and In1-xMnxAs when x≲0.10. On the other hand, the estimated TC of Ga1-xMnxAs saturates with an increase of x when x≳0.05, but that of (Ga0.5In0.5)1-xMnxAs and In1-xMnxAs does not saturate even when x>0.10. These results are in good agreement with the previous experimental results. Our calculated results predict that the TC of (Ga0.5In0.5)1-xMnxAs and In1-xMnxAs will be higher than that of Ga1-xMnxAs when x≳0.10.

  14. Local structures in mixed LixFe1-yMyPO4 (M=Co, Ni) electrode materials

    NASA Astrophysics Data System (ADS)

    Jalkanen, K.; Lindén, J.; Karppinen, M.

    2015-10-01

    We employ 57Fe Mössbauer spectroscopy as a local tool to probe electrical environments of Fe2+ and Fe3+ at different lithiation (x) and cation-substitution (y) levels in LixFe1-yMyPO4/C (M=Co, Ni) Li-ion battery electrode materials. Upon delithiation the local environment of Fe3+ remains unaffected for the parent y=0 system due to the LiFePO4/FePO4 phase separation, whereas for y>0 changes in the electrical environment are seen for Fe3+. When the Fe2+/Fe3+ redox couple is partially-delithiated, a decreasing quadrupole splitting value is observed for Fe3+ with increasing y, implying a more symmetric electrical environment. The increasing concentration of the Co2+/Ni2+ substituent introduces increasing amounts of Li atoms in the Fe3+-containing phase, and these nearest-neighbor Li atoms are suspected to cause the changes seen in the local environment of Fe3+.

  15. Engineering the Transformation Strain in LiMnyFe1-yPO4 Olivines for Ultrahigh Rate Battery Cathodes.

    PubMed

    Ravnsbæk, Dorthe B; Xiang, Kai; Xing, Wenting; Borkiewicz, Olaf J; Wiaderek, Kamila M; Gionet, Paul; Chapman, Karena W; Chupas, Peter J; Tang, Ming; Chiang, Yet-Ming

    2016-04-13

    Alkali ion intercalation compounds used as battery electrodes often exhibit first-order phase transitions during electrochemical cycling, accompanied by significant transformation strains. Despite ∼30 years of research into the behavior of such compounds, the relationship between transformation strain and electrode performance, especially the rate at which working ions (e.g., Li) can be intercalated and deintercalated, is still absent. In this work, we use the LiMnyFe1-yPO4 system for a systematic study, and measure using operando synchrotron radiation powder X-ray diffraction (SR-PXD) the dynamic strain behavior as a function of the Mn content (y) in powders of ∼50 nm average diameter. The dynamically produced strain deviates significantly from what is expected from the equilibrium phase diagrams and demonstrates metastability but nonetheless spans a wide range from 0 to 8 vol % with y. For the first time, we show that the discharge capacity at high C-rates (20-50C rate) varies in inverse proportion to the transformation strain, implying that engineering electrode materials for reduced strain can be used to maximize the power capability of batteries. PMID:26930492

  16. Molecular characterization and specific detection of Anaplasma species (AP-sd) in sika deer and its first detection in wild brown bears and rodents in Hokkaido, Japan.

    PubMed

    Moustafa, Mohamed Abdallah Mohamed; Lee, Kyunglee; Taylor, Kyle; Nakao, Ryo; Sashika, Mariko; Shimozuru, Michito; Tsubota, Toshio

    2015-12-01

    A previously undescribed Anaplasma species (herein referred to as AP-sd) has been detected in sika deer, cattle and ticks in Japan. Despite being highly similar to some strains of A. phagocytophilum, AP-sd has never been detected in humans. Its ambiguous epidemiology and the lack of tools for its specific detection make it difficult to understand and interpret the prevalence of this Anaplasma species. We developed a method for specific detection, and examined AP-sd prevalence in Hokkaido wildlife. Our study included 250 sika deer (Cervus nippon yesoensis), 13 brown bears (Ursus arctos yesoensis) and 252 rodents including 138 (Apodemus speciosus), 45 (Apodemus argenteus), 42 (Myodes rufocanus) and 27 (Myodes rutilus) were collected from Hokkaido island, northern Japan, collected during 2010 to 2015. A 770 bp and 382 bp segment of the 16S rRNA and gltA genes, respectively, were amplified by nested PCR. Results were confirmed by cloning and sequencing of the positive PCR products. A reverse line blot hybridization (RLB) based on the 16S rRNA gene was then developed for the specific detection of AP-sd. The prevalence of AP-sd by nested PCR in sika deer was 51% (128/250). We detected this Anaplasma sp. for the first time in wild brown bears and rodents with a prevalence of 15% (2/13) and 2.4% (6/252), respectively. The sequencing results of the 16S rRNA and gltA gene amplicons were divergent from the selected A. phagocytophilum sequences in GenBank. Using a newly designed AP-sd specific probe for RLB has enabled us to specifically detect this Anaplasma species. Besides sika deer and cattle, wild brown bears and rodents were identified as potential reservoir hosts for AP-sd. This study provided a high throughput molecular method that specifically detects AP-sd, and which can be used to investigate its ecology and its potential as a threat to humans in Japan. PMID:26431688

  17. Stochastic emergence of inflaton fluctuations in a SdS primordial universe with large-scale repulsive gravity from a 5D vacuum

    NASA Astrophysics Data System (ADS)

    Reyes, L. M.; Madriz Aguilar, J. E.; Bellini, M.

    2011-06-01

    We develop a stochastic approach to study scalar-field fluctuations of the inflaton field in an early inflationary universe with a black hole (BH), which is described by an effective 4D Schwarzschild-de Sitter (SdS) metric. This effective 4D metric is the induced metric on a 4D hypersurface, here representing our universe, which is obtained from a 5D Ricci-flat SdS static metric, after implementing a planar coordinate transformation. On this background, we found that at the end of the inflation, the squared fluctuations of the inflaton field are not exactly scale independent and result sensitive to the mass of the BH.

  18. NaxLi0.7-xNi1-yMnyO2 as a new positive electrode material for lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Chiba, Kazuki; Taguchi, Noboru; Shikano, Masahiro; Sakaebe, Hikari

    2016-04-01

    In this study, a new class of contenders for high-voltage and high-capacity positive electrode materials with the composition NaxLi0.7-xNi1-yMnyO2 (0.03 < x ≤ 0.25, 0.5 ≤ y ≤ 0.8) was synthesized by thermal treatment; these positive electrode materials synthesized by Na+/Li+ exchange using P3sbnd Na0.7Ni1-yMnyO2 (0.5 ≤ y ≤ 0.8) as the precursor exhibited a mixture of layered and spinel structures. The (dis)charge voltage-capacity curve of materials with these compositions significantly varied according to the residual Na and Mn content. Notably, HT-NaxLi0.7-xNi1-yMnyO2 (x = 0.093, y = 0.67) exhibited a maximum discharge capacity of 261 mA h g-1 at an average voltage of 3.36 V at 25 °C (between 2.0 and 4.8 V), which translates to an energy density of 943 W h kg-1. The obtained electrochemical performance is rationalized by the phase fractions of layered and spinel structures, which is triggered by the residual Na and Mn content in NaxLi0.7-xNi1-yMnyO2.

  19. Disilane-based cyclic deposition/etch of Si, Si:P and Si1-yCy:P layers: I. The elementary process steps

    NASA Astrophysics Data System (ADS)

    Hartmann, J. M.; Benevent, V.; Barnes, J. P.; Veillerot, M.; Deguet, C.

    2013-02-01

    We have benchmarked the 550 °C, 20 Torr growth of Si:P and Si1-yCy:P using SiH4 and Si2H6. P segregation has prevented us from reaching P+ ion concentrations in Si higher than a few 1019 cm-3 using SiH4; the resulting surface ‘poisoning’ led to a severe growth rate reduction. Meanwhile, [P+] increased linearly with the phosphine flow when using Si2H6 as the Si precursor; values as high as 1.7 × 1020 cm-3 were obtained. The Si:P growth rate using Si2H6 was initially stable then increased as the PH3 flow increased. Mono-methylsilane flows 6.5-10 times higher were needed with Si2H6 than with SiH4 to reach the same substitutional C concentrations in intrinsic Si1-yCy layers ([C]subst. up to 1.9%). Growth rates were approximately six times higher with Si2H6 than with SiH4, however. 30 nm thick Si1-yCy layers became rough as [C]subst. exceeded 1.6% (formation of increasing numbers of islands). We have also studied the structural and electrical properties of ‘low’ and ‘high’ C content Si1-yCy:P layers (˜ 1.5 and 1.8%, respectively) grown with Si2H6. Adding significant amounts of PH3 led to a reduction of the tensile strain in the films. This was due to the incorporation of P atoms (at the expense of C atoms) in the substitutional sites of the Si matrix. Si1-yCy:P layers otherwise became rough as the PH3 flow increased. Resistivities lower than 1 mΩ cm were nevertheless associated with those Si1-yCy:P layers, with P atomic concentrations at most 3.9 × 1020 cm-3. Finally, we have quantified the beneficial impact of adding GeH4 to HCl for the low-temperature etching of Si. Etch rates 12-36 times higher with HCl + GeH4 than with pure HCl were achieved at 20 Torr. Workable etch rates close to 1 nm min-1 were obtained at 600 °C (versus 750 °C for pure HCl), enabling low-temperature cyclic deposition/etch strategies for the selective epitaxial growth of Si, Si:P and Si1-yCy:P layers on patterned wafers.

  20. Ge1-ySny (y = 0.01-0.10) alloys on Ge-buffered Si: Synthesis, microstructure, and optical properties

    NASA Astrophysics Data System (ADS)

    Senaratne, C. L.; Gallagher, J. D.; Jiang, Liying; Aoki, Toshihiro; Smith, D. J.; Menéndez, J.; Kouvetakis, J.

    2014-10-01

    Novel hydride chemistries are employed to deposit light-emitting Ge1-ySny alloys with y ≤ 0.1 by Ultra-High Vacuum Chemical Vapor Deposition (UHV-CVD) on Ge-buffered Si wafers. The properties of the resultant materials are systematically compared with similar alloys grown directly on Si wafers. The fundamental difference between the two systems is a fivefold (and higher) decrease in lattice mismatch between film and virtual substrate, allowing direct integration of bulk-like crystals with planar surfaces and relatively low dislocation densities. For y ≤ 0.06, the CVD precursors used were digermane Ge2H6 and deuterated stannane SnD4. For y ≥ 0.06, the Ge precursor was changed to trigermane Ge3H8, whose higher reactivity enabled the fabrication of supersaturated samples with the target film parameters. In all cases, the Ge wafers were produced using tetragermane Ge4H10 as the Ge source. The photoluminescence intensity from Ge1-ySny/Ge films is expected to increase relative to Ge1-ySny/Si due to the less defected interface with the virtual substrate. However, while Ge1-ySny/Si films are largely relaxed, a significant amount of compressive strain may be present in the Ge1-ySny/Ge case. This compressive strain can reduce the emission intensity by increasing the separation between the direct and indirect edges. In this context, it is shown here that the proposed CVD approach to Ge1-ySny/Ge makes it possible to approach film thicknesses of about 1 μm, for which the strain is mostly relaxed and the photoluminescence intensity increases by one order of magnitude relative to Ge1-ySny/Si films. The observed strain relaxation is shown to be consistent with predictions from strain-relaxation models first developed for the Si1-xGex/Si system. The defect structure and atomic distributions in the films are studied in detail using advanced electron-microscopy techniques, including aberration corrected STEM imaging and EELS mapping of the average diamond-cubic lattice.

  1. Scan direction induced charging dynamics and the application for detection of gate to S/D shorts in logic devices

    NASA Astrophysics Data System (ADS)

    Lei, Ming; Tian, Qing; Wu, Kevin; Zhao, Yan

    2016-03-01

    Gate to source/drain (S/D) short is the most common and detrimental failure mechanism for advanced process technology development in Metal-Oxide-Semiconductor-Field-Effect-Transistor (MOSFET) device manufacturing. Especially for sub-1Xnm nodes, MOSFET device is more vulnerable to gate-S/D shorts due to the aggressive scaling. The detection of this kind of electrical short defect is always challenging for in-line electron beam inspection (EBI), especially new shorting mechanisms on atomic scale due to new material/process flow implementation. The second challenge comes from the characterization of the shorts including identification of the exact shorting location. In this paper, we demonstrate unique scan direction induced charging dynamics (SDCD) phenomenon which stems from the transistor level response from EBI scan at post metal contact chemical-mechanical planarization (CMP) layers. We found that SDCD effect is exceptionally useful for gate-S/D short induced voltage contrast (VC) defect detection, especially for identification of shorting locations. The unique SDCD effect signatures of gate-S/D shorts can be used as fingerprint for ground true shorting defect detection. Correlation with other characterization methods on the same defective location from EBI scan shows consistent results from various shorting mechanism. A practical work flow to implement the application of SDCD effect for in-line EBI monitor of critical gate-S/D short defects is also proposed, together with examples of successful application use cases which mostly focus on static random-access memory (SRAM) array regions. Although the capability of gate-S/D short detection as well as expected device response is limited to passing transistors and pull-down transistors due to the design restriction from standard 6-cell SRAM structure, SDCD effect is proven to be very effective for gate-S/D short induced VC defect detection as well as yield learning for advanced technology development.

  2. Thermal expansion of the Paintbrush tuff recovered from borehole USW SD-12 at pressures 30 MPa: Data report

    SciTech Connect

    Martin, R.J.; Noel, J.S.; Boyd, P.J.; Riggins, M.; Price, R.H.

    1997-09-01

    Experimental results are presented for 24 thermal expansion experiments performed on 5 welded specimens of the Paintbrush tuff recovered from borehole USW SD-12 at Yucca Mountain, Nevada. The thermal expansion experiments were performed at constant confining pressures between 1 and 30 MPa. On three specimens, the highest confining pressure measurements were performed first to inhibit thermally induced damage which might occur at lower confining pressures. At each confining pressure two complete thermal cycles were performed. The specimens were heated (to a nominal temperature of 250 C) and cooled at the nominal rate of 0.319 C per minute. The change in specimen length as a function of temperature was measured with two linear variable displacement transducers mounted on endcaps secured to the specimen. The strain increases with increasing temperature and the strain vs temperature curves are concave upward. On cooling, there is hysteresis at the higher temperatures at all confining pressures. The first heating/cooling cycle is anomalous; hysteresis is pronounced, and a permanent shortening of the specimen is observed at the termination of the cycle. The magnitude of the effect was similar for all five specimens regardless of whether the first cycle was carried out at the highest or lowest confining pressure. For subsequent cycles at all confining pressures, no permanent strain develops, and the strain versus temperature curves re very similar. The mean coefficients of thermal expansion ({alpha}) range from 7.9 to 10.8{sup {minus}6} C{sup {minus}1} at temperatures below 100 C, to 14.2 to 20.6 x 10{sup {minus}6} C{sup {minus}1} at temperatures approaching 250 C. The effect of confining pressure on thermal expansion is small. For temperatures above 175 C, the mean coefficients of thermal expansion decreases by 10--12% as the pressure increases from 1 to 30 MPa.

  3. Field Application of SD Bioline Malaria Ag Pf/Pan Rapid Diagnostic Test for Malaria in Greece

    PubMed Central

    Tseroni, Maria; Pervanidou, Danai; Tserkezou, Persefoni; Rachiotis, George; Pinaka, Ourania; Baka, Agoritsa; Georgakopoulou, Theano; Vakali, Annita; Dionysopoulou, Martha; Terzaki, Irene; Marka, Andriani; Detsis, Marios; Evlampidou, Zafiroula; Mpimpa, Anastasia; Vassalou, Evdokia; Tsiodras, Sotirios; Tsakris, Athanasios; Kremastinou, Jenny; Hadjichristodoulou, Christos

    2015-01-01

    Greece, a malaria-free country since 1974, has experienced re-emergence of Plasmodium vivax autochthonous malaria cases in some agriculture areas over the last three years. In early 2012, an integrated control programme (MALWEST Project) was launched in order to prevent re-establishment of the disease. In the context of this project, the rapid diagnostic tests (RDT) of SD Bioline Malaria Ag Pf/Pan that detects hrp-2 and pan-LDH antigens were used. The aim of this study was to assess the field application of the RDT for the P. vivax diagnosis in comparison to light microscopy and polymerase chain reaction (PCR). A total of 955 samples were tested with all three diagnostic tools. Agreement of RDT against microscopy and PCR for the diagnosis of P. vivax was satisfactory (K value: 0.849 and 0.976, respectively). The sensitivity, specificity and positive predictive value of RDT against PCR was 95.6% (95% C.I.: 84.8-99.3), 100% (95% C.I.: 99.6-100.0) and 100% (95% CI: 91.7-100.0) respectively, while the sensitivity, specificity and positive predictive value of RDT against microscopic examination was 97.4% (95% C.I.: 86.1-99.6), 99.4% (95% C.I.: 98.6-99.8) and 86.1% (95% CI: 72.1-94.7), respectively. Our results indicate that RDT performed satisfactory in a non-endemic country and therefore is recommended for malaria diagnosis, especially in areas where health professionals lack experience on light microscopy. PMID:25803815

  4. Effect of Cage Space on Behavior and Reproduction in Crl:CD(SD) and BN/Crl Laboratory Rats.

    PubMed

    Gaskill, Brianna N; Pritchett-Corning, Kathleen R

    2015-09-01

    The 2011 Guide for the Care and Use of Laboratory Animals contains recommendations regarding the amount of cage space for mothers with litters. Literature on cage-space use in breeding rats is sparse. We hypothesized that, if present, differences in behavior and reproduction would be detected between the smallest and largest cages tested. BN/Crl and Crl:CD(SD) rats were assigned to a cage treatment (580 cm(2), 758 cm(2), 903 cm(2), or 1355 cm(2)) and breeding configuration (single: male removed after birth of pups; pair: 1 male, 1 female) in a factorial design for 12 wk. All cages received 20 to 25 g of nesting material, and nests were scored weekly. Pups were weaned, sexed, and weighed between postnatal days 18 and 26. Adult behavior and location in the cage were videorecorded by scan-sampling on the litter's postnatal days 0 through 8 and 14 through 21. Press posture in adults and play behavior in pups were recorded according to a 1-0 sampling method. Differences in reproductive parameters were limited to expected differences related to rat genetic background and weaning weight in pups, which was lowest in the pair-bred CD rats in the smallest cages. Press posture in adults in the smaller cages increased as the pups became mobile. Pair-housed outbred rats in the smallest commercially available cage we tested showed behavioral changes and a lower pup weaning weight. Both laboratory animal scientists and caging manufacturers should address the challenge of providing more biologically relevant cage complexity rather than merely increasing floor space. PMID:26424247

  5. Effect of Cage Space on Behavior and Reproduction in Crl:CD(SD) and BN/Crl Laboratory Rats

    PubMed Central

    Gaskill, Brianna N; Pritchett-Corning, Kathleen R

    2015-01-01

    The 2011 Guide for the Care and Use of Laboratory Animals contains recommendations regarding the amount of cage space for mothers with litters. Literature on cage-space use in breeding rats is sparse. We hypothesized that, if present, differences in behavior and reproduction would be detected between the smallest and largest cages tested. BN/Crl and Crl:CD(SD) rats were assigned to a cage treatment (580 cm2, 758 cm2, 903 cm2, or 1355 cm2) and breeding configuration (single: male removed after birth of pups; pair: 1 male, 1 female) in a factorial design for 12 wk. All cages received 20 to 25 g of nesting material, and nests were scored weekly. Pups were weaned, sexed, and weighed between postnatal days 18 and 26. Adult behavior and location in the cage were videorecorded by scan-sampling on the litter's postnatal days 0 through 8 and 14 through 21. Press posture in adults and play behavior in pups were recorded according to a 1–0 sampling method. Differences in reproductive parameters were limited to expected differences related to rat genetic background and weaning weight in pups, which was lowest in the pair-bred CD rats in the smallest cages. Press posture in adults in the smaller cages increased as the pups became mobile. Pair-housed outbred rats in the smallest commercially available cage we tested showed behavioral changes and a lower pup weaning weight. Both laboratory animal scientists and caging manufacturers should address the challenge of providing more biologically relevant cage complexity rather than merely increasing floor space. PMID:26424247

  6. Six week swimming followed by acute uptakes of ginsenoside Rg1 may affect aerobic capacity of SD rats

    PubMed Central

    Haam, Saebom; Park, Hyon

    2015-01-01

    [Purpose] The purpose of this study is to examine the effects of six-weeks of endurance swim training and short-term intake of Rg1 on the expression of related proteins as well as improvement of aerobic exercise capacity in 8-week-old male SD rats. [Methods] The groups were divided into placebo (NP, n=6), Rg1 (NRG, n=6), exercise+placebo (EP, n=7), and exercise+Rg1 (ERG, n=7). On completion of the 6-week swimming exercise, Rg1-intake groups were treated with acute uptakes (3 times within 24hrs) of Rg1. After the treatment, all groups were subjected to a swim to exhaustion test, and then the mass of muscle tissue, mRNA expression level and activity of citrate synthase (CS) were analyzed on plantaris. [Results] There were no differences in the effect of 6-week swimming exercise and short-term intake of Rg1 on body weight and muscle mass between groups. Although the CS mRNA expression was elevated in the exercise group and combined treatment group, there was no significant difference in CS activity. Acute uptakes of Rg1 did not affect swimming time to exhaustion, but it was increased by 235% and 314% by the 6-weeks of exercise and combined treatment of exercise and Rg1, respectively, which suggests that the combined treatment increased the effect on the capacity of aerobic exercise. [Conclusion] Based on these results, it was confirmed that even a short-term treatment of Rg1 can give an additive effect for improvement of exercise function, and additional studies are needed for the mechanisms and modes of its working. PMID:27274464

  7. Nano-hydroxyapatite particles induce apoptosis on MC3T3-E1 cells and tissue cells in SD rats

    NASA Astrophysics Data System (ADS)

    Wang, Liting; Zhou, Gang; Liu, Haifeng; Niu, Xufeng; Han, Jingyun; Zheng, Lisha; Fan, Yubo

    2012-04-01

    While the advantages of nanomaterials are being increasingly recognized, their potential toxicity is drawing more and more attention and concern. In this study, we explore the toxicity mechanism of 20-30 nm rod-shaped hydroxyapatite (HA) nanoparticles in vitro and in vivo. The nanoparticles were prepared by precipitation and characterized by IR, XRD and TEM. Concentrations of 0 μg mL-1, 10 μg mL-1, 100 μg mL-1, 1 mg mL-1, and 10 mg mL-1 were applied to the MC3T3-E1 cells for viability (MTT-test). Based on the characteristic differences of the two methods of cell death, the morphological features of the MC3T3-E1 cell line co-cultured with nano-hydroxyapatite (n-HA) (10 mg mL-1) for 24 h were also observed by TEM. Furthermore, important serum biochemical markers and histopathological examinations were used to evaluate the potential toxicological effect of n-HA on the major organs of SD rats injected intraperitoneally with n-HA (33.3 mg kg-1 body weight). In the results, we found cell growth inhibition and apoptosis in MC3T3-E1 cells co-cultured with n-HA. Moreover, apoptosis but not necrosis was illustrated in liver and renal tissue by using histopathology slices and serum biochemical markers. It suggests that apoptosis may be the possible mechanism of n-HA toxicity and provides a better understanding of the biocompatibility of nanomaterials applied in human bone repair.

  8. Quantitative spectral analysis of the sdB star HD 188112: A helium-core white dwarf progenitor

    NASA Astrophysics Data System (ADS)

    Latour, M.; Heber, U.; Irrgang, A.; Schaffenroth, V.; Geier, S.; Hillebrandt, W.; Röpke, F. K.; Taubenberger, S.; Kromer, M.; Fink, M.

    2016-01-01

    Context. HD 188112 is a bright (V = 10.2 mag) hot subdwarf B (sdB) star with a mass too low to ignite core helium burning and is therefore considered a pre-extremely low-mass (ELM) white dwarf (WD). ELM WDs (M ≲ 0.3 M⊙) are He-core objects produced by the evolution of compact binary systems. Aims: We present in this paper a detailed abundance analysis of HD 188112 based on high-resolution Hubble Space Telescope (HST) near- and far-ultraviolet spectroscopy. We also constrain the mass of the star's companion. Methods: We use hybrid non-LTE model atmospheres to fit the observed spectral lines, and to derive the abundances of more than a dozen elements and the rotational broadening of metallic lines. Results: We confirm the previous binary system parameters by combining radial velocities measured in our UV spectra with the previously published values. The system has a period of 0.60658584 days and a WD companion with M ≥ 0.70 M⊙. By assuming a tidally locked rotation combined with the projected rotational velocity (v sin i = 7.9 ± 0.3 km s-1), we constrain the companion mass to be between 0.9 and 1.3 M⊙. We further discuss the future evolution of the system as a potential progenitor of an underluminous type Ia supernova. We measure abundances for Mg, Al, Si, P, S, Ca, Ti, Cr, Mn, Fe, Ni, and Zn, and for the trans-iron elements Ga, Sn, and Pb. In addition, we derive upper limits for the C, N, O elements and find HD 188112 to be strongly depleted in carbon. We find evidence of non-LTE effects on the line strength of some ionic species such as Si ii and Ni ii. The metallic abundances indicate that the star is metal-poor, with an abundance pattern most likely produced by diffusion effects.

  9. Self-limiting growth when using trimethyl bismuth (TMBi) in the metal-organic vapor phase epitaxy (MOVPE) of GaAs1-yBiy

    NASA Astrophysics Data System (ADS)

    Forghani, Kamran; Guan, Yingxin; Wood, Adam W.; Anand, Amita; Babcock, Susan E.; Mawst, Luke J.; Kuech, Thomas F.

    2014-06-01

    Theoretical and experimental studies have confirmed that the GaAs1-yBiy semiconductor alloy system has potential for long wavelength applications and devices with improved performance over other materials emitting at similar wavelengths. The growth of GaAs1-yBiy by metal-organic vapor phase epitaxy (MOVPE) remains a challenge; bismuth is not easily incorporated into the GaAs matrix due the large difference in electronegativity and covalent radii between As and Bi. These differences often lead to Bi surface segregation or very low incorporation rates of Bi into the GaAs matrix. We have studied the growth of GaAs1-yBiy quantum well structures using trimethyl bismuth as the Bi source. A reduced growth rate is observed with increasing Bi precursor flux into the growth reactor. Additionally, an increase in the growth time for the Bi-containing layer at very low growth temperatures does not lead to a corresponding increase in layer thickness, which is indicative of a near self-limiting growth. Complex compositional profiles deduced from combining x-ray diffraction analysis with the transmission electron microscopy investigations are used to develop a phenomenological model of the MOVPE growth of GaAs1-yBiy heterostructures which includes a complex interplay of the chemical surface species. The presence of a methyl-terminated surface, associated with the use of trimethyl Bi, particularly at low growth temperatures, leads to an effective “site blocking” by Bi precursor inhibiting the growth of GaAs1-yBiy hetero-structures.

  10. Hydride Properties and IRON-57 Mossbauer Effect Studies in TITANIUM(COPPER(1-Y)IRON(Y)) Intermetallic Compounds.

    NASA Astrophysics Data System (ADS)

    Zakaria, Ahmad

    1987-12-01

    The hydrogen absorption properties of the Ti(Cu _{rm 1-y}Fe _{rm y}) (0 <=q y <=q 1) intermetallic compound were systematically investigated. X-ray diffraction data indicated that the intermetallic compound adopted the gammaTiCu structure for 0 <=q y <=q.1 and crystallized in the TiFe structure for.5 <=q y <=q 1. A mixture of these two phases was observed for 0.1 < y <.5. The lattice parameters for the pure intermetallic compounds and hydrided samples were measured. The heat of hydride formation, DeltaH, as a function of Fe content was determined from pressure-composition isotherms and the Van't Hoff relation. In the composition range 0 <=q y <=q.1 the value of DeltaH varied from -74.3 kJ (mole H_{2 })^{-1} to -59.1 kJ (mole H_{2})^{ -1}. For.5 <=q y <=q 1 it went from -49.5 kJ (mole H_{2})^{-1} to -27.3 kJ (mole H_ {2})^{-1}. We have found that DeltaH values derived from a model proposed by Shilov et al. for calculating DeltaH of the multicomponent hydrides were in good agreement with the experimental data by about 3%. Other properties of the hydride such as hydrogen storage capacity and hysteresis effect were also found to be y dependent. Systematic ^{57}Fe Mossbauer effect studies were also carried out in the intermetallic compound and hydride systems with the emphasis on the isomer shift measurements. The total s-electron densities at the Fe nucleus (|psi_{ rm s}({rm o})|^ {2}) increases when the Fe content y decreases in the pure intermetallic compounds. | psi_{rm s}({rm o })|^{2} decreases with the introduction of the hydrogen. In the hydride system |psi_{rm s}({rm o})|^{2 } was found to be y independent. Interpretation of the data was based on the changes in | psi_{rm s}({rm o })|^{2} due to expansion and contraction of the host lattice and the electronic structure differences. The decrease in | psi_{rm s}({rm o })|^{2} due to the hydrogenation in the TiCu-like hydride (0 <=q y <=q.1) could be accounted for by the volume effect only. For TiFe-like hydride

  11. Defect engineering of complex semiconductor alloys: Cu2-2xMxO1-yXy

    NASA Astrophysics Data System (ADS)

    Lany, Stephan; Stevanovic, Vladan

    2013-03-01

    The electrical properties of semiconductors are generally controlled via doping, i.e., the incorporation of dilute concentrations of aliovalent impurity atoms, whereas the band structure properties (gap, effective masses, optical properties) are manipulated by alloying, i.e., the incorporation of much larger amounts of isovalent elements. Theoretical approaches usually address either doping or alloying, but rarely both problems at the same time. By combining defect supercell calculations, GW quasi-particle energy calculation, and thermodynamic modeling, we study the range of electrical and band structure properties accessible by alloying aliovalent cations (M = Mg, Zn, Cd) and isovalent anions (X = S, Se) in Cu2O. In order to extend dilute defect models to higher concentrations, we take into account the association/dissociation of defect pairs and complexes, as well as the composition dependence of the band gap and the band edge energies. Considering a composition window for the Cu2-2xMxO1-yXy alloys of 0 <= (x,y) <= 0.2, we predict a wide range of possible band gaps from 1.7 to 2.6 eV, and net doping concentrations between p = 1019 cm-3 and n = 1017cm-3, notably achieving type conversion from p- to n-type at Zn or Cd compositions around x = 0.1. This work is supported as part of the SunShot initiative by the U. S. Department of Energy, Office of Energy Efficiency and Renewable Energy under Contract No. DE-AC36-08GO28308 to NREL.

  12. Thermal stability against reduction of LaMn{sub 1-y}Co{sub y}O{sub 3} perovskites

    SciTech Connect

    Pecchi, Gina Campos, Claudia; Pena, Octavio

    2009-04-02

    Thermal and reduction-oxidation stability of substituted LaMn{sub 1-y}Co{sub y}O{sub 3} perovskite-type oxides (0.0 {<=} y{sub Co} {<=} 1.0) prepared by the citrate route have been studied by means of surface area, X-ray diffraction, FTIR spectroscopy and magnetic properties. The perovskite orthorhombic structure is found for y{sub Co} {<=} 0.5, with the exception of y{sub Co} = 0.1, which corresponds better to rhombohedral LaMnO{sub 3.15}. For y{sub Co} > 0.5 the diffraction profiles are quite similar to the cobaltite's rhombohedral structure. Magnetic iso-field studies (ZFC-FC) reveal that, for y{sub Co} {<=} 0.50, the system presents an antiferromagnetic canted-like ordering of the Mn/Co sublattice, in which the presence of divalent Co ion creates Mn{sup 3+}-Mn{sup 4+} pairs that interact ferromagnetically through the oxygen orbital. This interpretation is confirmed by the magnetization loops, in which the magnetic moment increases when substituting Mn for Co. Therefore, the general trend is: for y{sub Co} {<=} 0.5, the Co ions are inserted in the manganite structure and for y{sub Co} > 0.5, the Mn ions are inserted in cobaltite structure. The enhancement of the ferromagnetic properties and the thermal stability against reduction for y{sub Co} = 0.5 is attributed to optimized Co{sup 2+}-Mn{sup 4+} interactions.

  13. Thermoelectric Inhomogeneities in (Ag(sub 1-y)SbTe2)(sub x)(PbTe)(sub 1-x)

    NASA Technical Reports Server (NTRS)

    Snyder, G. Jeffrey; Chen, Nancy; Gascoin, Franck; Mueller, Eckhard; Karpinski, Gabriele; Stiewe, Christian

    2006-01-01

    A document presents a study of why materials of composition (Ag1 ySbTe2)0.05 (PbTe)0.95 [0< or = y < or = 1] were previously reported to have values of the thermoelectric figure of merit [ZT (where Z = alpha(sup 2)/rk, alpha is the Seebeck coefficient, r is electrical resistivity, k is thermal conductivity, and T is absolute temperature)] ranging from <1 to >2. In the study, samples of (AgSbTe2)0.05(PbTe)0.95, (Ag0.67SbTe2)0.05 (PbTe)0.95, and (Ag0.55SbTe2)0.05(PbTe)0.95 were prepared by melting followed, variously, by slow or rapid cooling. Analyses of these samples by x-ray diffraction, electron microscopy, and scanning-microprobe measurements of the Seebeck coefficient led to the conclusion that these materials have a multiphase character on a scale of the order of millimeters, even though they appear homogeneous in x-ray diffraction and electron microscopy. The Seebeck measurements showed significant variations, including both n-type and p-type behavior in the same sample. These variations were found to be consistent with observed variations of ZT. The rapidly quenched samples were found to be less inhomogeneous than were the furnace-cooled ones; hence, rapid quenching was suggested as a basis of research on synthesizing more nearly uniform high-ZT samples.

  14. Structural phase transitions of robust insulating Bi1-xLaxFe1-yTiyO3 multiferroics

    NASA Astrophysics Data System (ADS)

    Zhang, Linlin; Yu, Jian; Itoh, Mitsuru

    2014-03-01

    In contrast to leaky BiFeO3, of which two structural phase transitions of cycloidal modulated antiferromagnetic-paramagnetic and ferroelectric-paraelectric are observed below 850 °C, chemical co-substitution to form Bi1-xLaxFe1-yTiyO3 ternary solid solution makes these multiferroic ceramics become robust insulating low dielectric loss and exhibit rich structural phase transitions. Differential thermal analysis and temperature-dependent X-ray diffraction measurements probe four first-order structural phase transitions, e.g., TH = 305 °C, TN = 365 °C, TC = 810 °C, and TS = 830 °C observed in the Bi0.98La0.02Fe0.99Ti0.01O3 system, which are reasonably attributed to Brazovskii-type cycloidal modulated antiferromagnetic-helimagnetic (at TH) and helimagnetic-paramagnetic (at TN) magnetic phase transitions, ferroelectric-paraelectric (at TC) and rhombohedral-cubic (at TS) structural phase transitions, respectively. Magnetic phase transition temperatures change a little but ferroelectric and lattice structural phase transition temperatures decrease gradually with increasing co-substitution up to composition-induced rhombohedral-(pseudo-)cubic structural phase boundary. The first-order nature of magnetic phase transition and emergence of helimagnetic phase were attributed to Ti3+ d1 magnetic disorder distribution in the Fe3+ d5-O-Fe3+ d5 chains, while the first-order nature becomes weak with increasing co-substitution, owing to decreased ferroelectric rhombohedral lattice distortion. An intermediate rhombohedral paraelectric phase is discovered intervening between ferroelectric rhombohedral and paraelectric cubic phase, of which the temperature range defined by difference between TC and TS increases with increasing co-substitution. It was found that TC and TS are able to be predicted quantitatively by reduced mass of unit cell. These findings enrich our understanding of ferroic phase transitions and advance designing novel high temperature multiferroic compounds.

  15. Theory of the evolution of magnetic order in Fe1+yTe compounds with increasing interstitial iron

    NASA Astrophysics Data System (ADS)

    Ducatman, Samuel; Fernandes, Rafael M.; Perkins, Natalia B.

    2014-10-01

    We examine the influence of the excess of interstitial Fe on the magnetic properties of Fe1+yTe compounds. Because in iron chalcogenides the correlations are stronger than in the iron arsenides, we assume in our model that some of the Fe orbitals give rise to localized magnetic moments. These moments interact with each other via exchange interactions as well as phonon-mediated biquadratic interactions that favor a collinear double-stripe state, corresponding to the ordering vectors (±π/2,±π/2). The remaining Fe orbitals are assumed to be itinerant, giving rise to the first-principles derived Fermi surface displaying nesting features at momenta (π,0)/(0,π). Increasing the amount of itinerant electrons due to excess Fe, y, leads to changes in the Fermi surface and to the suppression of its nesting properties. As a result, due to the Hund's coupling between the itinerant and localized moments, increasing y leads to modifications in the local moments' exchange interactions via the multiorbital generalization of the long-range Ruderman-Kittel-Kasuya-Yosida (RKKY) interaction. By numerically computing the RKKY corrections and minimizing the resulting effective exchange Hamiltonian, we find, in general, that the excess electrons introduced in the system change the classical magnetic ground state from a double-stripe state to an incommensurate spiral, consistent with the experimental observations. We show that these results can be understood as a result of the suppression of magnetic spectral weight of the itinerant electrons at momenta (π,0)/(0,π), combined with the transfer of broad magnetic spectral weight from large to small momenta, promoted by the introduction of excess Fe.

  16. Investigation of Transport Anomalies in LANTHANUM(1-Y) STRONTIUM(Y)CHROMIUM(1-X)MANGANESE(X)OXYGEN(3)

    NASA Astrophysics Data System (ADS)

    Raffaelle, Ryne Patrick

    1990-08-01

    This dissertation presents an investigation of several anomalies associated with electronic transport in the La_{1-y}Sr_{y}Cr_{1-x}Mn_{x} O_3 series. The specific anomaly which prompted this study was a large decrease in electrical conductivity when small amounts of Mn were substituted for Cr in LaCrO _3. This decrease was followed by a sharp rise in the conductivity as the Mn content is increased. This conductivity minimum was unexpected due to the fact that LaMnO_3 was believed to have the same conduction mechanism (small polarons) and nearly the same activation energy as LaCrO_3, but a larger conductivity. A detailed set of electrical conductivity measurements was performed on the LaCr_{1-x}Mn_{x} O_3 series. The conductivity minimum has been attributed to an energy difference between polarons located on Cr or Mn ions as a result of this study. A crossover from multiple-trapping to percolation among energetically lower Mn sites qualitatively explained the conductivity of the LaCr_{1-x}Mn _{x}O _3 series. This explanation combined aspects from traditionally separate models of disordered electronic transport. Thermopower measurements were performed on the LaCr_{1-x}Mn _{x}O _3 series and a similar series in which 10 mol% Sr was substituted for La to investigate the crossover dependence on the carrier concentration. The concentration of small polarons in the Mn end members is much larger than was expected from naturally occurring structural defects. The expected increase in carrier concentration with Sr substitution was suppressed in nearly all Mn containing samples. This work was concluded by suggesting a possible Mn ^{+2}-Mn^{+4 } electronic structure which seems to resolve these problems.

  17. Planning and implementation of the on-comet operations of the instrument SD2 onboard the lander Philae of Rosetta mission

    NASA Astrophysics Data System (ADS)

    Di Lizia, P.; Bernelli-Zazzera, F.; Ercoli-Finzi, A.; Mottola, S.; Fantinati, C.; Remetean, E.; Dolives, B.

    2016-08-01

    The lander Philae of the Rosetta mission landed on the surface of the comet 67 P/Churyumov-Gerasimenko on November 12, 2014. Among the specific subsystems and instruments carried on Philae, the sampling, drilling and distribution (SD2) subsystem had the role of providing in-situ operations devoted to soil drilling, sample collection, and their distribution to three scientific instruments. After landing, a first sequence of scientific activities was carried out, relying mainly on the energy stored in the lander primary battery. Due to the limited duration and the communication delay, these activities had to be carried out automatically, with a limited possibility of developing and uploading commands from the ground. Philae's landing was not nominal and SD2 was operated in unexpected conditions: the lander was not anchored to the soil and leant on the comet surface shakily. Nevertheless, one sampling procedure was attempted. This paper provides an overview of SD2 operation planning and on-comet operations, and analyses SD2 achievements during the first science sequence of Philae's on-comet operations.

  18. EFFECTS OF 20 WEEK EXPOSURES IN FEMALE SPRAGUE-DAWLEY (S-D) RATS TO THE DRINKING WATER DISINFECTION BY-PRODUCT DIBROMOACETIC ACID

    EPA Science Inventory

    Effects of 20 week exposures in female Sprague-Dawley (S-D) rats to the drinking water disinfection by-product dibromoacetic acid. A S Murr and J M Goldman, Endocrinol. Br., RTD, NHEERL, ORD, US EPA, Res. Tri. Pk, NC. Sponsor: Audrey Cummings

    The drinking water disinfect...

  19. EFFECTS OF 20 WEEK EXPOSURES IN FEMALE SPRAGUE-DAWLEY (S-D) RATS TO DIBROMOACETIC ACID, A DRINKING WATER DISINFECTANT BY-PRODUCT

    EPA Science Inventory

    Effects of 20 week exposures in female Sprague-Dawley (S-D) rats to the drinking water disinfection by-product dibromoacetic acid. A S Murr and J M Goldman, Endocrinol. Br., RTD, NHEERL, ORD, US EPA, Res. Tri. Pk, NC. Sponsor: Audrey Cummings

    The drinking water disinfect...

  20. LONG-TERM SD-OCT/SLO IMAGING OF NEURORETINA AND RETINAL PIGMENT EPITHELIUM AFTER SUB-THRESHOLD INFRARED LASER TREATMENT OF DRUSEN

    PubMed Central

    MOJANA, FRANCESCA; BRAR, MANPREET; CHENG, LINGYUN; BARTSCH, DIRK-UWE G.; FREEMAN, WILLIAM R.

    2012-01-01

    PURPOSE To determine the long-term effect of sub-threshold diode laser treatment for drusen in patients with non-exudative age-related macular degeneration (AMD) with spectral domain optical coherence tomography combined with simultaneous scanning laser ophthalmoscope (SD-OCT/SLO). METHODS 8 eyes of 4 consecutive AMD patients with bilateral drusen previously treated with sub-threshold diode laser were imaged with SD-OCT/SLO. Abnormalities in the outer retina layers reflectivity as seen with SD-OCT/SLO were retrospectively analyzed and compared with color fundus pictures and autofluorescence images (AF) acquired immediately before and after the laser treatment. RESULTS A focal discrete disruptions in the reflectivity of the outer retinal layers was noted in 29% of the laser lesions. The junction in between the inner and outer segment of the photoreceptor was more frequently affected, with associated focal damage of the outer nuclear layer. Defects of the RPE were occasionally detected. These changes did not correspond to threshold burns on color fundus photography, but corresponded to focal areas of increased AF in the majority of the cases. CONCLUSIONS Sub-threshold diode laser treatment causes long-term disruption of the retinal photoreceptor layer as analyzed by SD-OCT/SLO. The concept that sub-threshold laser treatment can achieve a selected RPE effect without damage to rods and cones may be flawed. PMID:21157398

  1. Detailed Morphological Changes of Foveoschisis in Patient with X-Linked Retinoschisis Detected by SD-OCT and Adaptive Optics Fundus Camera.

    PubMed

    Akeo, Keiichiro; Kameya, Shuhei; Gocho, Kiyoko; Kubota, Daiki; Yamaki, Kunihiko; Takahashi, Hiroshi

    2015-01-01

    Purpose. To report the morphological and functional changes associated with a regression of foveoschisis in a patient with X-linked retinoschisis (XLRS). Methods. A 42-year-old man with XLRS underwent genetic analysis and detailed ophthalmic examinations. Functional assessments included best-corrected visual acuity (BCVA), full-field electroretinograms (ERGs), and multifocal ERGs (mfERGs). Morphological assessments included fundus photography, spectral-domain optical coherence tomography (SD-OCT), and adaptive optics (AO) fundus imaging. After the baseline clinical data were obtained, topical dorzolamide was applied to the patient. The patient was followed for 24 months. Results. A reported RS1 gene mutation was found (P203L) in the patient. At the baseline, his decimal BCVA was 0.15 in the right and 0.3 in the left eye. Fundus photographs showed bilateral spoke wheel-appearing maculopathy. SD-OCT confirmed the foveoschisis in the left eye. The AO images of the left eye showed spoke wheel retinal folds, and the folds were thinner than those in fundus photographs. During the follow-up period, the foveal thickness in the SD-OCT images and the number of retinal folds in the AO images were reduced. Conclusions. We have presented the detailed morphological changes of foveoschisis in a patient with XLRS detected by SD-OCT and AO fundus camera. However, the findings do not indicate whether the changes were influenced by topical dorzolamide or the natural history. PMID:26356828

  2. Detailed Morphological Changes of Foveoschisis in Patient with X-Linked Retinoschisis Detected by SD-OCT and Adaptive Optics Fundus Camera

    PubMed Central

    Akeo, Keiichiro; Kameya, Shuhei; Gocho, Kiyoko; Kubota, Daiki; Yamaki, Kunihiko; Takahashi, Hiroshi

    2015-01-01

    Purpose. To report the morphological and functional changes associated with a regression of foveoschisis in a patient with X-linked retinoschisis (XLRS). Methods. A 42-year-old man with XLRS underwent genetic analysis and detailed ophthalmic examinations. Functional assessments included best-corrected visual acuity (BCVA), full-field electroretinograms (ERGs), and multifocal ERGs (mfERGs). Morphological assessments included fundus photography, spectral-domain optical coherence tomography (SD-OCT), and adaptive optics (AO) fundus imaging. After the baseline clinical data were obtained, topical dorzolamide was applied to the patient. The patient was followed for 24 months. Results. A reported RS1 gene mutation was found (P203L) in the patient. At the baseline, his decimal BCVA was 0.15 in the right and 0.3 in the left eye. Fundus photographs showed bilateral spoke wheel-appearing maculopathy. SD-OCT confirmed the foveoschisis in the left eye. The AO images of the left eye showed spoke wheel retinal folds, and the folds were thinner than those in fundus photographs. During the follow-up period, the foveal thickness in the SD-OCT images and the number of retinal folds in the AO images were reduced. Conclusions. We have presented the detailed morphological changes of foveoschisis in a patient with XLRS detected by SD-OCT and AO fundus camera. However, the findings do not indicate whether the changes were influenced by topical dorzolamide or the natural history. PMID:26356828

  3. An Analysis on Teachers' Politeness Strategy and Student's Compliance in Teaching Learning Process at SD Negeri 024184 Binjai Timur Binjai--North Sumatra-Indonesia

    ERIC Educational Resources Information Center

    Manik, Sondang; Hutagaol, Juniati

    2015-01-01

    This study aims to find out the politeness strategies used by the teachers and how the politeness affects to the student's compliance. The focus is on directive and expressive speech acts. The subjects of this study were two teachers and the students of class II-A and II-B at SD 024184 Binjai Timur Binjai. The data was gathered by video audio…

  4. Automated geographic atrophy segmentation for SD-OCT images using region-based C-V model via local similarity factor

    PubMed Central

    Niu, Sijie; de Sisternes, Luis; Chen, Qiang; Leng, Theodore; Rubin, Daniel L.

    2016-01-01

    Age-related macular degeneration (AMD) is the leading cause of blindness among elderly individuals. Geographic atrophy (GA) is a phenotypic manifestation of the advanced stages of non-exudative AMD. Determination of GA extent in SD-OCT scans allows the quantification of GA-related features, such as radius or area, which could be of important value to monitor AMD progression and possibly identify regions of future GA involvement. The purpose of this work is to develop an automated algorithm to segment GA regions in SD-OCT images. An en face GA fundus image is generated by averaging the axial intensity within an automatically detected sub-volume of the three dimensional SD-OCT data, where an initial coarse GA region is estimated by an iterative threshold segmentation method and an intensity profile set, and subsequently refined by a region-based Chan-Vese model with a local similarity factor. Two image data sets, consisting on 55 SD-OCT scans from twelve eyes in eight patients with GA and 56 SD-OCT scans from 56 eyes in 56 patients with GA, respectively, were utilized to quantitatively evaluate the automated segmentation algorithm. We compared results obtained by the proposed algorithm, manual segmentation by graders, a previously proposed method, and experimental commercial software. When compared to a manually determined gold standard, our algorithm presented a mean overlap ratio (OR) of 81.86% and 70% for the first and second data sets, respectively, while the previously proposed method OR was 72.60% and 65.88% for the first and second data sets, respectively, and the experimental commercial software OR was 62.40% for the second data set. PMID:26977364

  5. Evaluation of SD BIOLINE Syphilis 3.0 for Rapid Diagnosis of Syphilis: Report from a Regional Sexually Transmitted Infection Reference Laboratory in North India

    PubMed Central

    Mehra, Bhanu; Bhattar, Sonali; Saxena, Shikhar; Rawat, Deepti; Bhalla, Preena

    2016-01-01

    Background: Serology is considered the mainstay of syphilis diagnosis. The limitations of the traditional serological methods and the advent and availability of novel immunochromatographic assays have led to the widespread application of rapid point-of-care procedures as screening tools for syphilis. However, these tests have not been extensively evaluated. This study was designed to evaluate the performance of a rapid syphilis diagnostic test known as SD BIOLINE Syphilis 3.0 (SD Biostandard Diagnostics Private Limited, Gurgaon, Haryana, India). Materials and Methods: A panel comprising of 50 venereal disease research laboratory reactive and 50 nonreactive sera was tested using SD BIOLINE Syphilis 3.0. The performance of the test was evaluated using IMMUTREP Treponema pallidum hemagglutination assay (TPHA) (OMEGA Diagnostics Limited, Scotland, United Kingdom) as the reference standard and sensitivity, specificity, and negative and positive predictive values were calculated. Results: The sensitivity, specificity, and positive and negative predictive values of SD BIOLINE Syphilis 3.0 were 92.86% (confidence interval of 95%: 80.52–98.50%), 98.28% (90.76-99.96%), 97.50% (86.84–99.94%), and 95.00% (86.08–98.96%), respectively, compared to TPHA as the gold standard. Conclusion: Keeping in view the high sensitivity and specificity of SD BIOLINE Syphilis 3.0, we conclude that the test can be used as a tool for rapid on-site diagnosis of syphilis and as an alternative to TPHA for detection of antibodies to Treponema pallidum. PMID:27013811

  6. Toward a consistent model of the B0.5IVe + sdO binary φ Persei.

    NASA Astrophysics Data System (ADS)

    Bozic, H.; Harmanec, P.; Horn, J.; Koubsky, P.; Scholz, G.; McDavid, D.; Hubert, A.-M.; Hubert, H.

    1995-12-01

    A detailed analysis of a very rich collection of spectroscopic and photometric observations of the bright Be star φ Per is presented. Earlier reports that φ Per is a double-lined spectroscopic binary consisting of two emission-line objects are confirmed. An orbital solution based on the emission-wing radial velocities for both stars has led to a determination of the orbital elements which defines the correct orbital phases. All data since the beginning of this century can be reconciled with a constant orbital period of 126.6731d+/-0.0071d. The new orbital solution gives lower masses than those found by earlier investigators, namely M_1_sin^3^i=16.35Msun_ and M_2_sin^3^i=1.69Msun_. These masses are in agreement with the recently derived spectral classes B0.5IVe and sdO6: for the primary and secondary, respectively. Long-term light variations are positively correlated with the emission strength, and in the U-B vs. B-V diagram the object has changed its apparent photometric type from a B supergiant toward an MS object. Dereddening of the mean seasonal UBV magnitudes from recent years (when spectra show the weakest recorded Balmer emission) leads to a photometric spectral type a bit earlier than B1V. An important and exciting finding is that the emission lines of both stars have been weakening simultaneously in recent years, which seems to indicate some kind of interaction between the binary components. The presence of rapid light variability is confirmed, but its more detailed analysis is postponed for another study. Low-amplitude orbital light variations with rather complicated light and color curves are found after the removal of long-term and rapid changes. The principal maxima and minima of the orbital light curves can be traced in both old and new photometry and can probably be attributed to specific circumstellar structures whose signatures are also seen spectroscopically. Finally, systematic secular changes in the shape and amplitude of the orbital radial

  7. Magnetic Characterization of Synthetic SD-like Pyrrhotite and Its Demagnetization under Hydrostatic Pressure up to 1.8 GPa

    NASA Astrophysics Data System (ADS)

    Bezaeva, N. S.; Chareev, D. A.; Rochette, P.; Kars, M.; Gattacceca, J.

    2014-12-01

    Monoclinic pyrrhotite (Fe7S8) is a common ferrimagnetic mineral in both terrestrial rocks and meteorites (e.g., SNC, Rumuruti chondrites…). It is also recognized as a candidate magnetic mineral for Martian magnetic anomalies. We synthesized SD-like monoclinic pyrrhotite at 245°C using the molten-salt synthesis method [1]. Here we characterize its magnetic properties including its behavior under hydrostatic pressure up to 1.8 GPa. Data were collected in the 10K to 360°C temperature range and include measurements of low-field magnetic susceptibility (χ0), thermomagnetic curves χ0(T), major hysteresis loops, back-field remanence demagnetization curves, first-order reversal curve (FORC), alternating field and pressure demagnetization of saturation isothermal remanent magnetization (SIRM or Mrs), low temperature MPMS datasets (field and frequency dependencies of χ0, field-cooled and zero-field-cooled remanence FC-ZFC and room temperature SIRM heating-cooling cycles) as well as X-ray diffraction (XRD) spectra. χ0(T) indicates a single Curie point at 320°C characteristic of monoclinic pyrrhotite. For application of hydrostatic pressure up to 1.8 GPa we used a nonmagnetic high-pressure cell of piston-cylinder type entirely made of "Russian alloy" (Ni57Cr40Al3) with 8 mm of inner diameter similar to the cell, described in [2]. Application of 1.8 GPa resulted in demagnetization (decrease in SIRM) of the sample by 38%. Repeated cycling from 1.8 GPa to atmospheric pressure and back resulted in further decrease in remanence by 44% (for 3 cycles). The characteristic Besnus transition of pyrrhotite is observed at ~34 K. The observed hysteresis parameters (Mrs/Ms=0.53, Bcr/Bc=1.17, Bcr=41 mT, where Ms is saturation magnetization, Bc and Bcr are coercivity and remanent coercivity, respectively) are consistent with pseudo-single-domain range, previously established in literature [3]. Superparamagnetic (SP) grains are not present in the sample as no frequency dependence of

  8. How to predict return to work after lumbar discectomy: answers from the NeuroPoint-SD registry.

    PubMed

    Than, Khoi D; Curran, Jill N; Resnick, Daniel K; Shaffrey, Christopher I; Ghogawala, Zoher; Mummaneni, Praveen V

    2016-08-01

    OBJECTIVE To date, the factors that predict whether a patient returns to work after lumbar discectomy are poorly understood. Information on postoperative work status is important in analyzing the cost-effectiveness of the procedure. METHODS An observational prospective cohort study was completed at 13 academic and community sites (NeuroPoint-Spinal Disorders [NeuroPoint-SD] registry). Patients undergoing single-level lumbar discectomy were included. Variables assessed included age, sex, body mass index (BMI), SF-36 physical function score, Oswestry Disability Index (ODI) score, presence of diabetes, smoking status, systemic illness, workers' compensation status, and preoperative work status. The primary outcome was working status within 3 months after surgery. Stepwise logistic regression analysis was performed to determine which factors were predictive of return to work at 3 months following discectomy. RESULTS There were 127 patients (of 148 total) with data collected 3 months postoperatively. The patients' average age at the time of surgery was 46 ± 1 years, and 66.9% of patients were working 3 months postoperatively. Statistical analyses demonstrated that the patients more likely to return to work were those of younger age (44.5 years vs 50.5 years, p = 0.008), males (55.3% vs 28.6%, p = 0.005), those with higher preoperative SF-36 physical function scores (44.0 vs 30.3, p = 0.002), those with lower preoperative ODI scores (43.8 vs 52.6, p = 0.01), nonsmokers (83.5% vs 66.7%, p = 0.03), and those who were working preoperatively (91.8% vs 26.2%, p < 0.0001). When controlling for patients who were working preoperatively (105 patients), only age was a statistically significant predictor of postoperative return to work (44.1 years vs 51.1 years, p = 0.049). CONCLUSIONS In this cohort of lumbar discectomy patients, preoperative working status was the strongest predictor of postoperative working status 3 months after surgery. Younger age was also a predictor

  9. GIT1Y321 phosphorylation is required for ERK1/2- and PDGF-dependent VEGF secretion from osteoblasts to promote angiogenesis and bone healing.

    PubMed

    Rui, Ze; Li, Xiang; Fan, Jin; Ren, Yongxin; Yuan, Yufeng; Hua, Zhengzhe; Zhang, Ning; Yin, Guoyong

    2012-10-01

    Bone healing depends on vascular endothelial growth factor (VEGF) secretion from osteoblasts to promote angiogenesis. We examined the influence of the tyrosine 321 site of G protein-coupled receptor kinase interacting protein 1 (GIT1) on platelet-derived growth factor (PDGF)-induced VEGF synthesis in vitro and on bone healing in vivo. Cultured osteoblasts were prepared from calvaria of 1-2-day-old rats. The phospho-activation of extracellular signal-regulated kinases 1/2 (ERK1/2), GIT1, the interaction between GIT1 and ERK1/2, and VEGF mRNA expression were measured in response to PDGF. In addition, PDGF was applied following pretreatment with the MEK1/2 inhibitor PD98059 or the Src inhibitor PP2. We mutated tyrosines 293 or 321 of GIT1 individually to phenylalanine (mutants GIT1Y293F and GIT1Y321F) and incorporated these mutants and native GIT1 into lentivirus vectors. The relationship between GIT1 and ERK1/2, and VEGF mRNA expression in cultured osteoblasts were detected after infection with GIT1WT-, GIT1Y293F- and GIT1Y321F-expressing lentivirus in response to PDGF. Bone healing and expression of VEGF and the angiogenic marker PECAM-1 were evaluated after infection at the fracture site. Activation of ERK1/2 by phosphorylation, GIT1 tyrosine phosphorylation, GIT1-ERK1/2 interaction, and VEGF mRNA expression were all significantly increased in osteoblasts after PDGF stimulation, but all responses were dramatically inhibited by pretreatment with PD98059. Tyrosine phosphorylation, GIT1 interaction with ERK1/2, and VEGF mRNA expression were dramatically inhibited by pretreatment with PP2 or infection with GIT1Y321F-expressing lentivirus. Expression of VEGF and PECAM-1 was significantly lower at the fracture sites infected with GIT1Y321F-expressing lentivirus and bone healing was significantly delayed compared to fracture sites infected with GIT1WT. In conclusion, tyrosine 321 of GIT1 is a critical phosphorylation site for GIT1 interaction with ERK1/2, regulation of

  10. Growth, strain relaxation properties and high-κ dielectric integration of mixed-anion GaAs{sub 1-y}Sb{sub y} metamorphic materials

    SciTech Connect

    Zhu, Y.; Clavel, M.; Goley, P.; Hudait, M. K.

    2014-10-07

    Mixed-anion, GaAs{sub 1-y}Sb{sub y} metamorphic materials with a wide range of antimony (Sb) compositions extending from 15% to 62%, were grown by solid source molecular beam epitaxy (MBE) on GaAs substrates. The impact of different growth parameters on the Sb composition in GaAs{sub 1-y}Sb{sub y} materials was systemically investigated. The Sb composition was well-controlled by carefully optimizing the As/Ga ratio, the Sb/Ga ratio, and the substrate temperature during the MBE growth process. High-resolution x-ray diffraction demonstrated a quasi-complete strain relaxation within each composition of GaAs{sub 1-y}Sb{sub y}. Atomic force microscopy exhibited smooth surface morphologies across the wide range of Sb compositions in the GaAs{sub 1-y}Sb{sub y} structures. Selected high-κ dielectric materials, Al{sub 2}O{sub 3}, HfO{sub 2}, and Ta{sub 2}O{sub 5} were deposited using atomic layer deposition on the GaAs{sub 0.38}Sb{sub 0.62} material, and their respective band alignment properties were investigated by x-ray photoelectron spectroscopy (XPS). Detailed XPS analysis revealed a valence band offset of >2 eV for all three dielectric materials on GaAs{sub 0.38}Sb{sub 0.62}, indicating the potential of utilizing these dielectrics on GaAs{sub 0.38}Sb{sub 0.62} for p-type metal-oxide-semiconductor (MOS) applications. Moreover, both Al{sub 2}O{sub 3} and HfO{sub 2} showed a conduction band offset of >2 eV on GaAs{sub 0.38}Sb{sub 0.62}, suggesting these two dielectrics can also be used for n-type MOS applications. The well-controlled Sb composition in several GaAs{sub 1-y}Sb{sub y} material systems and the detailed band alignment analysis of multiple high-κ dielectric materials on a fixed Sb composition, GaAs{sub 0.38}Sb{sub 0.62}, provides a pathway to utilize GaAs{sub 1-y}Sb{sub y} materials in future microelectronic and optoelectronic applications.

  11. Tailoring the Valence Band Offset of Al2O3 on Epitaxial GaAs(1-y)Sb(y) with Tunable Antimony Composition.

    PubMed

    Liu, Jheng-Sin; Clavel, Michael; Hudait, Mantu K

    2015-12-30

    Mixed-anion, GaAs1-ySby metamorphic materials with tunable antimony (Sb) compositions extending from 0 to 100%, grown by solid source molecular beam epitaxy (MBE), were used to investigate the evolution of interfacial chemistry under different passivation conditions. X-ray photoelectron spectroscopy (XPS) was used to determine the change in chemical state progression as a function of surface preclean and passivation, as well as the valence band offsets, conduction band offsets, energy band parameters, and bandgap of atomic layer deposited Al2O3 on GaAs1-ySby for the first time, which is further corroborated by X-ray analysis and cross-sectional transmission electron microscopy. Detailed XPS analysis revealed that the near midpoint composition, GaAs0.45Sb0.55, passivation scheme exhibits a GaAs-like surface, and that precleaning by HCl and (NH4)2S passivation are mandatory to remove native oxides from the surface of GaAsSb. The valence band offsets, ΔEv, were determined from the difference in the core level to the valence band maximum binding energy of GaAs1-ySby. A valence band offset of >2 eV for all Sb compositions was found, indicating the potential of utilizing Al2O3 on GaAs1-ySby (0 ≤ y ≤ 1) for p-type metal-oxide-semiconductor (MOS) applications. Moreover, Al2O3 showed conduction band offset of ∼2 eV on GaAs1-ySby (0 ≤ y ≤ 1), suggesting Al2O3 dielectric can also be used for n-type MOS applications. The surface passivation of GaAs0.45Sb0.55 materials and the detailed band alignment analysis of Al2O3 high-κ dielectrics on tunable Sb composition, GaAs1-ySby materials, provides a pathway to utilize GaAsSb materials in future microelectronic and optoelectronic applications. PMID:26642121

  12. Tricritical Lifshitz point in the temperature-pressure-composition diagram for (PbySn1-y)2P2(SexS1-x)6 ferroelectrics

    NASA Astrophysics Data System (ADS)

    Andersson, O.; Chobal, O.; Rizak, I.; Rizak, V.

    2009-11-01

    The heat capacity of Sn2P2S6 ferroelectric crystals has been measured under quasihydrostatic pressures up to 0.7 GPa. The analysis of the heat-capacity and literature data for the birefringence shows that the tricritical point of Sn2P2S6 is in the 0.20-0.25 GPa range. Moreover, in the approximation of a linear change in the free-energy expansion coefficients, with respect to concentration and pressure, thermodynamic trajectories have been constructed for (PbySn1-y)2P2(SexS1-x)6 solid solutions. We have thereby identified the region of the T-p-y-x diagram for (PbySn1-y)2P2(SexS1-x)6 showing the tricritical Lifshitz point.

  13. Variation and fractionation of lithium isotope ratios within single tourmaline crystals in the pegmatites of the Black Hills, SD

    NASA Astrophysics Data System (ADS)

    Gross, M.; Nabelek, P. I.

    2012-12-01

    Lithium isotopes are quickly becoming a valuable geochemical tool, providing insight into a broad range of studies. Li isotopes have been utilized in studies with subjects ranging from mantle processes to planetary accretion on stars. Yet, as an emerging technique, a number of uncertainties remain to be resolved. Two basic questions must be answered in order to apply isotope studies in a meaningful way: How do isotopes fractionate from each other and what do the isotope ratios mean? Previous studies on intra-crystal Li isotope signatures in tourmaline are extremely limited. One study showed roughly homogenous isotope profile using secondary ion mass spectroscopy (SIMS) analysis (Ludwig et al. 2011). If Li isotopes are in fact variable within individual crystals, however, it has implications for previous models of pegmatite formation reached using Li isotopes, as well as the root cause of Li isotope fractionation in tourmaline. For this study, tourmaline samples were collected from several texturally different pegmatite localities in the Black Hills, SD. Lithium concentrations and isotope ratios were measured along numerous points in a tourmaline crystal to discern how they change within a single crystal. The tourmaline was dissolved by an alkali fusion technique. Concentrations were determined at the University of Missouri using a Perkin-Elmer Optima 3300 Inductively Coupled Plasma Optical Emission Spectrometer (ICP-OES). Isotope measurements were performed at University of Maryland-College Park by a Nu Plasma Multi-collector ICP-MS. The procedure followed the three-column cation exchange chromatography method. Additionally, elemental mapping was performed on one sample using the JEOL JXA-8200 Superprobe at Washington University in St. Louis. Results of this research reveal that extreme fractionation of Li is possible within single tourmaline crystals. The δ7Li values measured are among the highest measured in rocks, though the average for each crystal falls

  14. On the 300km discontinuity with Conversion Phases SdP in the Tonga-Fiji Region

    NASA Astrophysics Data System (ADS)

    Zhou, Y.; Sui, Y.

    2011-12-01

    Conversion phases SdP are powerful for retrieving information of velocity interfaces of deep structure of Earth's interior. The high sensitivity seismograph network Japan (Hi-net) has about 800 seismometers which can provide digital waveform data from since 2004 through internet. The difference between the focal depths and the depth of 300 km discontinuity determines the sizes of Fresnel zones at the discontinuity for the waveform data from the seismic network, so seismic waveform of six earthquakes with depths from 145 to 220km between 2004 and 2011 beneath Tonga-Fiji region are retrieved from Hi-net (www.hinet.bosai.go.jp). The magnitudes of the events used are Mb 5.0-5.7 which means there are good signal-noise ratios and relatively simple source time functions. In this study, the focal depths determined with pP phases are provided by EHB database for those before 2006 and www.globalcmt.org for those after that year. After filtering with 0.2-1.0Hz (e.g. Castle and Creager, JGR, 2000) and manually selection, waveform data are divided to 5-8 groups related to the regional locations of seismometers and proceeded with N-th root slant-stack method, then we can get the related vespegram in differential time vs slowness. There are 38 vespegrams for 6 events. From the vespegrams, the conversion phases are picked according to the references of the theoretical values of the differential times and slownesses. The parameters read from vespegrams are inverted with IASP91 model to the depths and locations of conversion points. The conversion points related to 300 km discontinuity are distributed from 302 to 328km in the Fuji-Tonga region. For the vespegrams from one certain event but sub-networks, the depth variation are less than 20 km, mostly are less than 11km. Especially, the depth variation of the event 6 are just 8 km. So in the square region with 200 * 300 km, the lateral variation of the depth of the 300 km discontinuity is relatively small. Comparing with the former

  15. Influence of interstitial Fe to the phase diagram of Fe1+yTe1−xSex single crystals

    PubMed Central

    Sun, Yue; Yamada, Tatsuhiro; Pyon, Sunseng; Tamegai, Tsuyoshi

    2016-01-01

    Superconductivity (SC) with the suppression of long-range antiferromagnetic (AFM) order is observed in the parent compounds of both iron-based and cuprate superconductors. The AFM wave vectors are bicollinear (π, 0) in the parent compound FeTe different from the collinear AFM order (π, π) in most iron pnictides. Study of the phase diagram of Fe1+yTe1−xSex is the most direct way to investigate the competition between bicollinear AFM and SC. However, presence of interstitial Fe affects both magnetism and SC of Fe1+yTe1−xSex, which hinders the establishment of the real phase diagram. Here, we report the comparison of doping-temperature (x-T) phase diagrams for Fe1+yTe1−xSex (0 ≤ x ≤ 0.43) single crystals before and after removing interstitial Fe. Without interstitial Fe, the AFM state survives only for x < 0.05, and bulk SC emerges from x = 0.05, and does not coexist with the AFM state. The previously reported spin glass state, and the coexistence of AFM and SC may be originated from the effect of the interstitial Fe. The phase diagram of Fe1+yTe1−xSex is found to be similar to the case of the “1111” system such as LaFeAsO1−xFx, and is different from that of the “122” system. PMID:27577047

  16. Observation of multiple superconducting gaps in Fe1+yTe1-xSex via a nanoscale approach to point-contact spectroscopy

    NASA Astrophysics Data System (ADS)

    Peng, Haibing; De, Debtanu; Wu, Zheng; Diaz-Pinto, Carlos

    2012-11-01

    We report a novel experimental approach to point-contact Andreev reflection spectroscopy with diagnostic capability via a unique design for nanoscale normal metal/superconductor devices with excellent thermomechanical stability, and have employed this method to unveil the existence of two superconducting energy gaps in iron chalcogenide Fe1+yTe1-xSex, which is crucial for understanding its pairing mechanism. This work opens up new opportunities to study gap structures in superconductors and elemental excitations in solids.

  17. Reduced pressure chemical vapor deposition of Si/Si1-yCy heterostructures for n-type metal-oxide-semiconductor transistors

    NASA Astrophysics Data System (ADS)

    Hartmann, J. M.; Ernst, T.; Loup, V.; Ducroquet, F.; Rolland, G.; Lafond, D.; Holliger, P.; Laugier, F.; Semeria, M. N.; Deleonibus, S.

    2002-09-01

    We have grown by reduced pressure chemical vapor deposition Si/Si1-yCy/Si heterostructures for electrical purposes. The incorporation of substitutional carbon atoms into Si creates a carrier confinement in the channel region of metal-oxide-semiconductor (MOS) transistors. Indeed, tensile strain Si1-yCy layers present a type II band alignment with Si, with a conduction band offset of the order of 60 meV per at. % of substitutional carbon atoms. For small SiH3CH3 flows, all the incoming carbon atoms are incorporated into substitutional sites. At 600 degC, when the SiH3CH3 flow increases, the substitutional carbon concentration saturates at 1.12%. Meanwhile, the total carbon concentration CT still increases, following a simple law: CT/(1-CT)=0.88 * F(SiH3CH3)/F(SiH4). This is a sign that a growing number of C atoms incorporates into interstitial sites. The hydrogenated chemistry adopted does not enable one to achieve selectivity over SiO2-masked wafers, but does not however generate any adverse loading effect. We have integrated Si/Si1-yCy/Si stacks (which have been shown to be stable versus conventional gate oxidations and electrical activation anneals) into the channel region of ultrashort gate length (50 nm) nMOS transistors. Secondary ions mass spectrometry profiling has shown that C atoms segregate from the Si1-yCy layer into the Si cap and the SiO2 gate, but also that they block the diffusion paths of B coming from the antipunch through layer towards the gate, generating very retrograde doping profiles. The addition of C leads to a degradation of the electron mobility which seems to be linked to the high amount of C atoms into interstitial sites.

  18. A systematic study of the optical and electrical properties of Ge1-ySny and Ge1-x-ySixSn y semiconductor alloys

    NASA Astrophysics Data System (ADS)

    Harris, Thomas R.

    In order to fully utilize newly developed Ge1-ySny and Ge1-x-ySixSny materials for new novel optoelectronic devices, the optical and electrical properties of these alloys were investigated using photoluminescence (PL) and Hall-effect measurements. Direct bandgap PL emission was observed from almost all the samples, making them very promising candidates for Si-based light emitting devices. T-dependent PL studies also indicate that the indirect-to-direct bandgap transition of Ge1-ySny alloys might take place at a much lower Sn content than the theory predicts. T-dependent Hall-effect measurements showed both degenerate parallel conducting layers as well as a conductivity type change from p to n at around 370-435 K, which could affect the operation of devices made from these materials. Etch studies were performed to determine the properties of the epilayers alone. Reasonable results for the average volume carrier density in the film were obtained. It was also found that there exists high level of surface states at the surface of almost all the samples. These studies should be very useful for the development of practical devices based on Ge1-ySny alloys.

  19. The marine isolate Novosphingobium sp. PP1Y shows specific adaptation to use the aromatic fraction of fuels as the sole carbon and energy source.

    PubMed

    Notomista, Eugenio; Pennacchio, Francesca; Cafaro, Valeria; Smaldone, Giovanni; Izzo, Viviana; Troncone, Luca; Varcamonti, Mario; Di Donato, Alberto

    2011-04-01

    Novosphingobium sp. PP1Y, isolated from a surface seawater sample collected from a closed bay in the harbour of Pozzuoli (Naples, Italy), uses fuels as its sole carbon and energy source. Like some other Sphingomonads, this strain can grow as either planktonic free cells or sessile-aggregated flocks. In addition, this strain was found to grow as biofilm on several types of solid and liquid hydrophobic surfaces including polystyrene, polypropylene and diesel oil. Strain PP1Y is not able to grow on pure alkanes or alkane mixtures but is able to grow on a surprisingly wide range of aromatic compounds including mono, bi, tri and tetracyclic aromatic hydrocarbons and heterocyclic compounds. During growth on diesel oil, the organic layer is emulsified resulting in the formation of small biofilm-coated drops, whereas during growth on aromatic hydrocarbons dissolved in paraffin the oil layer is emulsified but the drops are coated only if the mixtures contain selected aromatic compounds, like pyrene, propylbenzene, tetrahydronaphthalene and heterocyclic compounds. These peculiar characteristics suggest strain PP1Y has adapted to efficiently grow at the water/fuel interface using the aromatic fraction of fuels as the sole carbon and energy source. PMID:21258788

  20. Relaxation Dynamics and Threading Dislocations in ZnSe and ZnS y Se1- y /GaAs (001) Heterostructures

    NASA Astrophysics Data System (ADS)

    Kujofsa, T.; Cheruku, S.; Yu, W.; Outlaw, B.; Xhurxhi, S.; Obst, F.; Sidoti, D.; Bertoli, B.; Rago, P. B.; Suarez, E. N.; Jain, F. C.; Ayers, J. E.

    2013-09-01

    The design of lattice-mismatched semiconductor devices requires a predictive model for strains and threading dislocation densities. Previous work enabled modeling of uniform layers but not the threading dislocations in device structures with arbitrary compositional grading. In this work we present a kinetic model for lattice relaxation which includes misfit-threading dislocation interactions, which have not been considered in previous annihilation-coalescence models. Inclusion of these dislocation interactions makes the kinetic model applicable to compositionally graded structures, and we have applied it to ZnSe/GaAs (001) and ZnS y Se1- y /GaAs (001) heterostructures. The results of the kinetic model are consistent with the observed threading dislocation behavior in ZnSe/GaAs (001) uniform layers, and for graded ZnS y Se1- y /GaAs (001) heterostructures the kinetic model predicts that the threading dislocation density may be reduced by the inclusion of grading buffer layers employing compositional overshoot. This "dislocation compensation" effect is consistent with our high-resolution x-ray diffraction experimental results for graded ZnS y Se1- y /GaAs (001) structures grown by photoassisted metalorganic vapor-phase epitaxy.

  1. Cation and Vacancy Disorder in U1-yNdyO2.00-X Alloys

    SciTech Connect

    Barabash, Rozaliya I.; Voit, Stewart L.; Aidhy, Dilpuneet S.; Lee, Seung Min; Knight, Travis W.; Sprouster, David J.; Ecker, Lynne E.

    2015-09-14

    In this study, the intermixing and clustering of U/Nd, O, and vacancies were studied by both laboratory and synchrotron-based x-ray diffraction in U1-yNdyO2-X alloys. It was found that an increased holding time at the high experimental temperature during initial alloy preparation results in a lower disorder of the Nd distribution in the alloys. Adjustment of the oxygen concentration in the U1-yNdyO2-X alloys with different Nd concentrations was accompanied by the formation of vacancies on the oxygen sublattice and a nanocrystalline component. The lattice parameters in the U1-yNdyO2-X alloys were also found to deviate significantly from Vegard's law when the Nd concentration was high (53%) and decreased with increasing oxygen concentration. Such changes indicate the formation of large vacancy concentrations during oxygen adjustment at these high temperatures. Finally, the change in the vacancy concentration after the oxygen adjustment was estimated relative to Nd concentration and oxygen stoichiometry.

  2. Compositional dependence of the crystal symmetry of Eu3+-doped (SrxBa1-x)2CaWyMo1-yO6 phosphors

    NASA Astrophysics Data System (ADS)

    Sletnes, M.; Valmalette, J. C.; Grande, T.; Einarsrud, M.-A.

    2016-01-01

    Two series of A-site and B-site Eu3+ doped (SrxBa1-x)2CaWyMo1-yO6 double perovskite phosphor materials were prepared via a modified Pechini sol-gel route; (SrxBa1-x)1.96Eu0.02K0.02CaWyMo1-yO6 and (SrxBa1-x)2Ca0.96Eu0.02Li0.02WyMo1-yO6 (x and y=0, 0.25, 0.50, 0.75, 1). The Sr/Ba ratio was the main determinant for the crystal symmetry of the series, while variation in the W/Mo ratio did influence the crystal symmetry significantly. The crystal structure evolved with Sr/Ba ratio from cubic Fm 3 bar m for x=0, via tetragonal I 4 / m for x=0.25, to monoclinic P 21 / n for x≥0.5, as verified by Rietveld refinement of X-ray diffractograms as well as by Raman spectroscopy. The reported boundaries for the compositionally induced phase transitions are in very good agreement with reported optical properties.

  3. Production, purification, and characterization of antifungal metabolite from Pseudomonas aeruginosa SD12, a new strain obtained from tannery waste polluted soil.

    PubMed

    Dharni, Seema; Alam, Mansoor; Kalani, Komal; Abdul-Khaliq; Samad, Abdul; Srivastava, Santosh Kumar; Patra, Dharani Dhar

    2012-05-01

    A new strain, SD12, was isolated from tannery waste polluted soil and identified as Pseudomonas aeruginosa on the basis of phenotypic traits and by comparison of 16S rRNA sequences. This bacterium exhibited broad-spectrum antagonistic activity against phytopathogenic fungi. The strain produced phosphatases, cellulases, proteases, pectinases, and HCN and also retained its ability to produce hydroxamate-type siderophore. A bioactive metabolite was isolated from P. aeruginosa SD12 and was characterized as 1-hydroxyphenazine ((1-OH-PHZ) by nuclear magnetic resonance (NMR) spectral analysis. The strain was used as a biocontrol agent against root rot and wilt disease of pyrethrum caused by Rhizoctonia solani. The stain is also reported to increase the growth and biomass of Plantago ovata. The purified compound, 1-hydroxyphenazine, also showed broad-spectrum antagonistic activity towards a range of phytopathogenic fungi, which is the first report of its kind. PMID:22561863

  4. Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon.

    PubMed Central

    Capon, C; Maes, E; Michalski, J C; Leffler, H; Kim, Y S

    2001-01-01

    This paper describes structural characterization by NMR, MS and degradative studies of mucin glycans from normal human descending colon obtained freshly at autopsy. The saccharides were mainly based on core 3 (GlcNAcbeta1-3GalNAc). Among the terminal saccharide determinants Sd(a)/Cad-antigen-like structures were prominent, and Lewis x, sialyl Lewis x and sulphated Lewis x were found as minor components, whereas blood group H and A antigenic determinants were absent. The saccharides were markedly different from those of mucins from colon cancers or colon cancer cell lines analysed so far, in which cores 1 and 2 are prominent features, and in which various other terminal determinants have been found, but not Sd(a)/Cad. PMID:11577689

  5. Detailed software design of an ultra-parallel ultra-high speed SD-OCT for real-time 4D display at 12 volume/second

    NASA Astrophysics Data System (ADS)

    Hiro-Oka, H.; Choi, D.; Shimizu, K.; Ohbayashi, K.

    2012-01-01

    We report on the software design of an ultra-parallel ultra-high speed spectral domain optical coherence tomography (SD-OCT) system. In our system, optical de-multiplexers divide an interferogram into 320 light every 18.7 GHz frequency, instead of a refractive grating for spectroscopy so far used in conventional SD-OCT. These optical elements enable to get rid of a re-sampling process and contribute to reduce the load of computing. The fast Fourier transform (FFT) is performed by field-programmable gate array (FPGA) and real-time 3D OCT images are created on graphics processing unit (GPU). Our system achieves a real-time 3D OCT image display (4D display) with an A-scan, B-scan, and volume rate of 10 MHz, 4 kHz, and 12 volumes per second, respectively.

  6. Optimization of Cry3A Yields in Bacillus thuringiensis by Use of Sporulation-Dependent Promoters in Combination with the STAB-SD mRNA Sequence

    PubMed Central

    Park, Hyun-Woo; Ge, Baoxue; Bauer, Leah S.; Federici, Brian A.

    1998-01-01

    The insecticidal activity of Bacillus thuringiensis strains toxic to coleopterous insects is due to Cry3 proteins assembled into small rectangular crystals. Toxin synthesis in these strains is dependent primarily upon a promoter that is active in the stationary phase and a STAB-SD sequence that stabilizes the cry3 transcript-ribosome complex. Here we show that significantly higher yields of Cry3A can be obtained by using dual sporulation-dependent cyt1Aa promoters to drive the expression of cry3Aa when the STAB-SD sequence is included in the construct. The Cry3A yield per unit of culture medium obtained with this expression system was 12.7-fold greater than that produced by DSM 2803, the wild-type strain of B. thuringiensis from which Cry3Aa was originally described, and 1.4-fold greater than that produced by NB176, a mutant of the same strain containing two or three copies of cry3Aa, which is the active ingredient of the commercial product Novodor, used for control of beetle pests. The toxicities of Cry3A produced with this construct or the wild-type strain were similar when assayed against larvae of the cottonwood leaf beetle, Chrysomela scripta. The volume of Cry3A crystals produced with cyt1Aa promoters and the STAB-SD sequence was 1.3-fold that of typical bipyramidal Cry1 crystals toxic to lepidopterous insects. The dual-promoter/STAB-SD system offers an additional method for potentially improving the efficacy of insecticides based on B. thuringiensis. PMID:9758822

  7. Lattice distortion-induced phase transformations in La{sub 1-y}Pr{sub y}MnO{sub 3+{delta}} manganites

    SciTech Connect

    Bukhanko, F. N.

    2013-04-15

    The structural and magnetic phase transformations that occur in the system of self-doped La{sub 1-y}Pr{sub y}MnO{sub 3+{delta}} ({delta} Almost-Equal-To 0.1, 0 {<=} y {<=} 1) manganites in the temperature range 4.2-300 K are studied by X-ray diffraction and measuring the temperature and field dependences of dc magnetization. The low-temperature magnetic phase transformations induced by the substitution of Pr for La correlate well with the structural phase transformations at T = 300 K, which indicates a strong coupling of the electronic and magnetic subsystems of La{sub 1-y}Pr{sub y}MnO{sub 3+{delta}} manganites with the crystal lattice. The anomalies of the magnetic and structural properties detected in this work in the form of peaks and inflection points in the concentration dependences of the magnetization and lattice parameters of the pseudocubic phase of La{sub 1-y}Pr{sub y}MnO{sub 3+{delta}} (0.1 {<=} y {<=} 0.7) in the temperature range 4.2-300 K are explained in terms of the existing concepts of the effect of Fermi surface nesting on the renormalization of the density of states and the hole dispersion near E{sub F} in the presence of a strong coupling of holes with low-frequency optical phonons, which results in their transformation into quasiparticles. The narrow peak in the magnetization curve M(y) of La{sub 1-y}Pr{sub y}MnO{sub 3+{delta}} that is detected near y = 0.3 at T = 4.2 K is assumed to correspond to the peak of coherence of quasiparticles with a low energy of coupling with the crystal lattice near E{sub F}, which was found earlier in the photoelectron emission spectra of manganites. The disappearance of the narrow magnetization peak with increasing Pr concentration is explained by the transition of charge carriers from the mode of 'light' holes weakly coupled to one of the soft phonons to the mode of 'heavy' holes strongly coupled to several phonons. The transition between phases with strongly different effective quasiparticle masses proceeds

  8. Microstructure analyses and thermoelectric properties of Ag{sub 1-x}Pb{sub 18}Sb{sub 1+y}Te{sub 20}

    SciTech Connect

    Perlt, S.; Hoeche, Th.; Dadda, J.; Mueller, E.; Bauer Pereira, P.; Hermann, R.; Sarahan, M.; Pippel, E.; Brydson, R.

    2012-09-15

    This study reports microstructural investigations of long-term annealed Ag{sub 1-x}Pb{sub m}Sb{sub 1+y}Te{sub 2+m} (m=18, x=y=0, hereinafter referred to as AgPb{sub 18}SbTe{sub 20}) (Lead-Antimony-Silver-Tellurium, LAST-18) as well as of Ag{sub 1-x}Pb{sub 18}Sb{sub 1+y}Te{sub 20}, i.e. Ag-deficient and Sb-excess LAST-18 (x{ne}0,y{ne}0), respectively. Two different length scales are explored. The micrometer scale was evaluated by SEM to analyze the volume fraction and the number of secondary phases as well as the impact of processing parameters on the homogeneity of bulk samples. For AgPb{sub 18}SbTe{sub 20}, site-specific FIB liftout of TEM lamellae from thermoelectrically characterized samples was accomplished to investigate the structure on the nanometer scale. High-resolution TEM and energy-filtered TEM were performed to reveal shape and size distribution of nanoprecipitates, respectively. A hypothesis concerning the structure-property relationship is set out within the frame of a gradient annealing experiment. This study is completed by results dealing with inhomogeneities on the micrometer scale of Ag{sub 1-x}Pb{sub 18}Sb{sub 1+y}Te{sub 20} and its electronic properties. Highlights: Black-Right-Pointing-Pointer SEM and TEM microstructure investigation of long-term annealed AgPb{sub 18}SbTe{sub 20}. Black-Right-Pointing-Pointer SEM and thermoelectric studies on Ag{sub 1-x}Pb{sub 18}Sb{sub 1+y}Te{sub 20}. Black-Right-Pointing-Pointer Discussion concerning structure-property relationship in long-term annealed AgPb{sub 18}SbTe{sub 20}. Black-Right-Pointing-Pointer Correlation between Ag{sub 1-x}Pb{sub 18}Sb{sub 1+y}Te{sub 20} microscale structure and electronic properties.

  9. Surface free energy ( γsd) of active carbons determined by inverse gas chromatography: influences of the origin of precursors, the burn off level and the chemical modification

    NASA Astrophysics Data System (ADS)

    Cossarutto, L.; Vagner, C.; Finqueneisel, G.; Weber, J. V.; Zimny, T.

    2001-06-01

    The dispersive component of the surface free energies ( γsd) of commercial active carbons (AC) from various origins were determined by inverse gas chromatography at infinite dilution (IGC-ID). This method discriminates clearly the AC produced from wood (and activated/carbonised with phosphoric acid) and those from coconut-shell (carbonised and steam activated at 850°C). The values for the last AC (from coconut) are twice higher than the values for AC of wood origin. The structure and shape of the pores have to be considered to explain these values. It seems that for AC, IGC-ID globally characterises the most energetic micropores. This can be observed, in this work, by two ways: (i) washing of commercial AC (chemically activated) allows to liberate a part of the micropores blocked by soluble phosphate and consequently increases the γsd value; (ii) modifying coconuts AC by chemical treatment (formamide) results in a strong decrease of both microporosity and γsd value. On the contrary, thermal activation of the modified AC increases at the same time the microporosity and the surface free energy. Finally, we demonstrate that the IGC method is also an useful tool to monitor in situ the evolutions of the surface properties of carbonaceous materials.

  10. Effects of Onion (Allium cepa L.) Extract Administration on Intestinal α-Glucosidases Activities and Spikes in Postprandial Blood Glucose Levels in SD Rats Model

    PubMed Central

    Kim, Sun-Ho; Jo, Sung-Hoon; Kwon, Young-In; Hwang, Jae-Kwan

    2011-01-01

    Diets high in calories and sweetened foods with disaccharides frequently lead to exaggerated postprandial spikes in blood glucose. This state induces immediate oxidant stress and free radicals which trigger oxidative stress-linked diabetic complications. One of the therapeutic approaches for decreasing postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes, α-amylase and α-glucosidases, in the digestive organs. Therefore, the inhibitory activity of Korean onion (Allium cepa L.) extract against rat intestinal α-glucosidases, such as sucrase, maltase, and porcine pancreatic α-amylase were investigated in vitro and in vivo. The content of quercetin in ethyl alcohol extract of onion skin (EOS) was 6.04 g/100 g dried weight of onion skin. The in vitro half-maximal inhibitory concentrations (IC50) of EOS and quercetin, a major phenolic in onion, on rat intestinal sucrase were 0.40 and 0.11 mg/mL, respectively. The postprandial blood glucose lowering effects of EOS and quercetin were compared to a known type 2 diabetes drug (Acarbose), a strong α-glucosidase inhibitor in the Sprague-Dawley (SD) rat model. In rats fed on sucrose, EOS significantly reduced the blood glucose spike after sucrose loading. The area under the blood glucose-time curve (AUClast) in EOS-treated SD rats (0.5 g-EOS/kg) was significantly lower than in untreated SD rats (259.6 ± 5.1 vs. 283.1 ± 19.2 h·mg/dL). The AUClast in quercetin-treated SD rats (0.5 g-quercetin/kg) was similar to in EOS-treated group (256.1 ± 3.2 vs. 259.6 ± 5.1 h·mg/dL). Results from this study indicates that although quercetin does have blood glucose lowering potential via α-glucosidase inhibition, there are other bioactive compounds present in onion skin. Furthermore, the effects of two weeks administration of EOS in a high carbohydrate-dietary mixture (Pico 5053) on sucrase and maltase activities in intestine were evaluated in SD rat model. Compared to

  11. Modeling the System Parameters of 2M 1533+3759: A New Longer Period Low-Mass Eclipsing sdB+dM Binary

    NASA Astrophysics Data System (ADS)

    For, B.-Q.; Green, E. M.; Fontaine, G.; Drechsel, H.; Shaw, J. S.; Dittmann, J. A.; Fay, A. G.; Francoeur, M.; Laird, J.; Moriyama, E.; Morris, M.; Rodríguez-López, C.; Sierchio, J. M.; Story, S. M.; Strom, A.; Wang, C.; Adams, S. M.; Bolin, D. E.; Eskew, M.; Chayer, P.

    2010-01-01

    We present new photometric and spectroscopic observations for 2M 1533+3759 (= NSVS 07826147), the seventh eclipsing subdwarf B star + M dwarf (sdB+dM) binary ever found. It has an orbital period of 0.16177042 days, or ~3.88 hr, significantly longer than the 2.3-3.0 hr periods of the other known eclipsing sdB+dM systems. Spectroscopic analysis of the hot primary yields T eff = 29230 ± 125 K, log g = 5.58 ± 0.03, and log N(He)/N(H) = -2.37 ± 0.05. The sdB velocity amplitude is K 1 = 71.1 ± 1.0 km s-1. The only detectable light contribution from the secondary is due to the surprisingly strong reflection effect, whose peak-to-peak BVRI amplitudes are 0.10, 0.13, 0.15, and 0.19 mag, respectively. Light-curve modeling produced several solutions corresponding to different values of the system mass ratio, q (M 2/M 1), but only one is consistent with a core helium burning star, q = 0.301. The orbital inclination is 86fdg6. The sdB primary mass is M 1 = 0.376 ± 0.055 M sun and its radius is R 1 = 0.166 ± 0.007 R sun. 2M 1533+3759 joins PG 0911+456 (and possibly also HS 2333+3927) in having an unusually low mass for an sdB star. SdB stars with masses significantly lower than the canonical value of 0.48 M sun, down to as low as 0.30 M sun, were theoretically predicted by Han et al., but observational evidence has only recently begun to confirm the existence of such stars. The existence of core helium burning stars with masses lower than 0.40-0.43 M sun implies that at least some sdB progenitors have initial main-sequence masses of 1.8-2.0 M sun or more, i.e., they are at least main-sequence A stars. The orbital separation in 2M 1533+3759 is a = 0.98 ± 0.04R sun. The secondary has M 2 = 0.113 ± 0.017 M sun, R 2 = 0.152 ± 0.005R sun, and T_eff_{2} = 3100 ± 600 K, consistent with a main-sequence M5 star. If 2M 1533+3759 becomes a cataclysmic variable (CV), its orbital period will be 1.6 hr, below the CV period gap.

  12. Comparative analysis of high-performance infrared avalanche InxGa1-xAsyP1-y and Hg1-xCdxTe heterophotodiodes

    NASA Astrophysics Data System (ADS)

    Kholodnov, Viacheslav; Drugova, Albina; Nikitin, Mikhail; Chekanova, Galina

    2012-10-01

    Technology of infrared (IR) avalanche photodiodes (APDs) gradually moves from simple single element APD to 2D focal plane arrays (FPA). Spectral covering of APDs is expanded continuously from classic 1.3 μm to longer wavelengths due to using of narrow-gap semiconductor materials like Hg1-xCdxTe. APDs are of great interest to developers and manufacturers of different optical communication, measuring and 3D reconstruction thermal imaging systems. Major IR detector materials for manufacturing of high-performance APDs became heteroepitaxial structures InxGa1-xAsyP1-y and Hg1-xCdxTe. Progress in IR APD technology was achieved through serious improvement in material growing techniques enabling forming of multilayer heterostuctures with separate absorption and multiplication regions (SAM). Today SAM-APD design can be implemented both on InxGa1-xAsyP1-y and Hg1-xCdxTe multilayer heteroepitaxial structures. To create the best performance optimal design avalanche heterophotodiode (AHPD) it is necessary to carry out a detailed theoretical analysis of basic features of generation, avalanche breakdown and multiplication of charge carriers in proper heterostructure. Optimization of AHPD properties requires comprehensive estimation of AHPD's pixel performance depending on pixel's multi-layer structure design, layers doping, distribution of electric field in the structure and operating temperature. Objective of the present article is to compare some features of 1.55 μm SAM-AHPDs based on InxGa1-xAsyP1-y and Hg1-xCdxTe.

  13. Photoluminescence of A- and B-site Eu3+-substituted (SrxBa1-x)2CaWyMo1-yO6 phosphors

    NASA Astrophysics Data System (ADS)

    Sletnes, M.; Lindgren, M.; Valmalette, J. C.; Wagner, N. P.; Grande, T.; Einarsrud, M.-A.

    2016-05-01

    The photoluminescence of two series of A- and B-site Eu3+ substituted (SrxBa1-x)2CaWyMo1-yO6 double perovskite phosphor materials, (SrxBa1-x)1.96Eu0.02K0.02CaWyMo1-yO6 and (SrxBa1-x)2Ca0.96Eu0.02Li0.02WyMo1-yO6 (x and y=0, 0.25, 0.50, 0.75, and 1), were studied systematically as a function of stoichiometry and crystal structure. The Eu3+ lattice sites controlled by co-doping with either K or Li were confirmed by Raman spectroscopy. The variation in integrated emission intensity and emission colour over the experimental matrix was examined using statistical tools, and the observed trends were rationalized based on the physical and electronic structure of the phosphors. Phosphors with Eu on B-site with maximum Sr content had remarkably higher emission intensities than all other materials, but the emission was more orange than red due to domination of the 5D0-7F1 (595 nm) transition of Eu3+. The relative intensities of the 5D0-7F2 (615 nm) and 5D0-7F1 transitions of Eu3+, and thus the red-shift of the emission, decreased linearly with increasing Sr content in the A-site Eu-substituted phosphors, and reached a maximum for Sr1.96Eu0.02K0.02CaW0.25Mo0.75O6. A maximum external quantum efficiency of 17% was obtained for the phosphor Sr2Ca0.7Eu0.15Li0.15W0.5Mo0.5O6 with Eu on B-site.

  14. Anomalous dependence of c-axis polarized Fe B1g phonon mode with Fe and Se concentrations in Fe1+yTe1-xSex

    NASA Astrophysics Data System (ADS)

    Um, Y. J.; Subedi, A.; Toulemonde, P.; Ganin, A. Y.; Boeri, L.; Rahlenbeck, M.; Liu, Y.; Lin, C. T.; Carlsson, S. J. E.; Sulpice, A.; Rosseinsky, M. J.; Keimer, B.; Le Tacon, M.

    2012-02-01

    We report on an investigation of the lattice dynamical properties in a range of Fe1+yTe1-xSex compounds, with special emphasis on the c-axis polarized vibration of Fe with B1g symmetry, a Raman active mode common to all families of Fe-based superconductors. We have carried out a systematic study of the temperature dependence of this phonon mode as a function of Se x and excess Fe y concentrations. In parent compound Fe1+yTe, we observe an unconventional broadening of the phonon between room temperature and magnetic ordering temperature TN. The situation smoothly evolves toward a regular anharmonic behavior as Te is substituted for Se and long-range magnetic order is replaced by superconductivity. Irrespective to Se contents, excess Fe is shown to provide an additional damping channel for the B1g phonon at low temperatures. We performed density functional theory ab initio calculations within the local density approximation to calculate the phonon frequencies, including magnetic polarization and Fe nonstoichiometry in the virtual crystal approximation. We obtained a good agreement with the measured phonon frequencies in the Fe-deficient samples, while the effects of Fe excess are poorly reproduced. This may be due to excess Fe-induced local magnetism and low-energy magnetic fluctuations that cannot be treated accurately within these approaches. As recently revealed by neutron scattering and muon spin rotation studies, these phenomena occur in the temperature range where anomalous decay of the B1g phonon is observed and suggests a peculiar coupling of this mode with local moments and spin fluctuations in Fe1+yTe1-xSex.

  15. Distribution of impurity states and charge transport in Zr0.25Hf0.75Ni1+xSn1-ySby nanocomposites

    NASA Astrophysics Data System (ADS)

    Liu, Yuanfeng; Makongo, Julien P. A.; Page, Alexander; Sahoo, Pranati; Uher, Ctirad; Stokes, Kevin; Poudeu, Pierre F. P.

    2016-02-01

    Energy filtering of charge carriers in a semiconducting matrix using atomically coherent nanostructures can lead to a significant improvement of the thermoelectric figure of merit of the resulting composite. In this work, several half-Heusler/full-Heusler (HH/FH) nanocomposites with general compositions Zr0.25Hf0.75Ni1+xSn1-ySby (0≤x≤0.15 and y=0.005, 0.01 and 0.025) were synthesized in order to investigate the behavior of extrinsic carriers at the HH/FH interfaces. Electronic transport data showed that energy filtering of carriers at the HH/FH interfaces in Zr0.25Hf0.75Ni1+xSn1-ySby samples strongly depends on the doping level (y value) as well as the energy levels occupied by impurity states in the samples. For example, it was found that carrier filtering at HH/FH interfaces is negligible in Zr0.25Hf0.75Ni1+xSn1-ySby (y=0.01 and 0.025) composites where donor states originating from Sb dopant dominate electronic conduction. However, we observed a drastic decrease in the effective carrier density upon introduction of HH/FH interfaces for the mechanically alloyed Zr0.25Hf0.75Ni1+xSn0.995Sb0.005 samples where donor states from unintentional Fe impurities contribute the largest fraction of conduction electrons. This work demonstrates the ability to synergistically integrate the concepts of doping and energy filtering through nanostructuring for the optimization of electronic transport in semiconductors.

  16. Experimental oxygen potentials of U1-yPryO2± x and thermodynamic assessment of the U-Pr-O system

    DOE PAGESBeta

    McMurray, Jake W.; Silva, Chinthaka M.

    2015-12-09

    Thermogravimetric analysis (TGA) was used to determine the oxygen potentials of fluorite urania-praseodymia (U1-yPryO2± x) solid solutions for y = 0.10 and 0.20 between 1000 and 1500 °C. A thermodynamic assessment of U-Pr-O system was performed using the CALPHAD (CALculation of PHAse Diagrams) method. Furthermore, the models well reproduce the TGA measurements and the computed phase relations are in good agreement with those proposed from an X-ray diffraction investigation.

  17. Experimental oxygen potentials for U1-yPryO2±x and thermodynamic assessment of the U-Pr-O system

    NASA Astrophysics Data System (ADS)

    McMurray, J. W.; Silva, C. M.

    2016-03-01

    Thermogravimetric analysis (TGA) was used to determine the oxygen potentials of fluorite urania-praseodymia (U1-yPryO2±x) solid solutions for y = 0.10 and 0.20 between 1000 and 1500 °C. A thermodynamic assessment of U-Pr-O system was performed using the CALPHAD (CALculation of PHAse Diagrams) method. The models well reproduce the TGA measurements and the computed phase relations are in good agreement with those proposed from an X-ray diffraction investigation.

  18. SYNTHESIS AND PIEZOELECTRIC PROPERTIES OF (Ba1-xCax)(Ti1-yZry)O3 BY A NOVEL COMPOSITE-HYDROXIDE-MEDIATED APPROACH

    NASA Astrophysics Data System (ADS)

    Kimura, Takeshi; Yin, Shu; Hashimoto, Takatoshi; Sasaki, Atushi; Tokano, Yuichi; Sato, Tsugio

    2012-06-01

    High purity (Ba1-xCax)(Ti1-yZry)O3((x,y)=(0.00,0.00)-(0.50,0.50)) were synthesized by a composite-hydroxide-mediated approach at 200°C using a sealed tube with a rolling system. The powders with an average size of 50 nm in diameter and narrow size distribution were produced. The highest electromechanical coupling factor kr was 36.1% ((x,y) = (0.05,0.03)) and highest mechanical quality factor Qm was 256 ((x,y) = (0.11,0.13)).

  19. Urbach rule and disordering processes in Cu6P(S1-xSex)5Br1-yIy superionic conductors

    NASA Astrophysics Data System (ADS)

    Kranjčec, M.; Studenyak, I. P.; Kurik, M. V.

    2006-04-01

    Compositional behavior of Urbach absorption edge is studied as well as the effect of compositional disordering on the parameters of exciton phonon interaction, phase transition temperatures and electric conductivity in Cu6P(S1-xSex)5Br1-yIy superionic solid solutions. The effect of different types of disordering on the optical absorption processes and specific features of compositional changes in the absorption edge spectra under S→Se and Br→I anion substitution in the mixed crystals are investigated. (x, T) phase diagrams for Cu6P(S1-xSex)5X (X=I, Br) solid solutions are studied.

  20. Three ways to solve the orbit of KIC 11 558 725: a 10-day beaming sdB+WD binary with a pulsating subdwarf

    NASA Astrophysics Data System (ADS)

    Telting, J. H.; Østensen, R. H.; Baran, A. S.; Bloemen, S.; Reed, M. D.; Oreiro, R.; Farris, L.; Ottosen, T. A.; Aerts, C.; Kawaler, S. D.; Heber, U.; Prins, S.; Green, E. M.; Kalomeni, B.; O'Toole, S. J.; Mullally, F.; Sanderfer, D. T.; Smith, J. C.; Kjeldsen, H.

    2012-08-01

    The recently discovered subdwarf B (sdB) pulsator KIC 11 558 725 is one of the 16 pulsating sdB stars detected in the Kepler field. It features a rich g-mode frequency spectrum, with a few low-amplitude p-modes at short periods. This makes it a promising target for a seismic study aiming to constrain the internal structure of this star, and of sdB stars ingeneral. We have obtained ground-based spectroscopic radial-velocity measurements of KIC 11 558 725 based on low-resolution spectra in the Balmer-line region, spanning the 2010 and 2011 observing seasons. From these data we have discovered that KIC 11 558 725 is a binary with period P = 10.05 d, and that the radial-velocity amplitude of the sdB star is 58 km s-1. Consequently the companion of the sdB star has a minimum mass of 0.63 M⊙, and is therefore most likely an unseen white dwarf. We analyse the near-continuous 2010-2011 Kepler light curve to reveal the orbital Doppler-beaming effect, giving rise to light variations at the 238 ppm level, which is consistent with the observed spectroscopic orbital radial-velocity amplitude of the subdwarf. We use the strongest 70 pulsation frequencies in the Kepler light curve of the subdwarf as clocks to derive a third consistent measurement of the orbital radial-velocity amplitude, from the orbital light-travel delay. The orbital radius asdBsini = 11.5 R⊙ gives rise to a light-travel time delay of 53.6 s, which causes aliasing and lowers the amplitudes of the shortest pulsation frequencies, unless the effect is corrected for. We use our high signal-to-noise average spectra to study the atmospheric parameters of the sdB star, deriving Teff = 27 910 K andlog g = 5.41 dex, and find that carbon, nitrogen and oxygen are underabundant relative to the solar mixture. Furthermore, we analyse the Kepler light curve for its pulsational content and extract more than 160 significant frequencies.We investigate the pulsation frequencies for expected period spacings and rotational

  1. Effects of Soluble Phosphate on Phosphate-Solubilizing Characteristics and Expression of gcd Gene in Pseudomonas frederiksbergensis JW-SD2.

    PubMed

    Zeng, Qingwei; Wu, Xiaoqin; Wen, Xinyi

    2016-02-01

    Phosphate-solubilizing bacteria have the ability of solubilizing mineral phosphate in soil and promoting growth of plants, but the activity of phosphate solubilization is influenced by exogenous soluble phosphate. In the present study, the effects of soluble phosphate on the activity of phosphate solubilization, acidification of media, growth, and organic acid secretion of phosphate-solubilizing bacterium Pseudomonas frederiksbergensis JW-SD2 were investigated under six levels of soluble phosphate conditions. The activity of phosphate solubilization decreased with the increase of soluble phosphate concentration, accompanying with the increase of media pH. However, the growth was promoted by adding soluble phosphate. Production of gluconic, tartaric, and oxalic acids by the strain was reduced with the increase of concentration of soluble phosphate, while acetic and pyruvic acids showed a remarkable increase. Gluconic acid predominantly produced by the strain at low levels of soluble phosphate showed that this acid was the most efficient organic acid in phosphate solubilization. Pyrroloquinoline quinone-glucose dehydrogenase gene gcd (pg5SD2) was cloned from the strain, and the expressions of pg5SD2 gene were repressed gradually with the increase of concentration of soluble phosphate. The soluble phosphate regulating the transcription of the gcd gene is speculated to underlie the regulation of the secretion of gluconic acid and subsequently the regulation of the activity of phosphate solubilization. Future research needs to consider a molecular engineering strategy to reduce the sensitivity of PSB strain to soluble phosphate via modification of the regulatory mechanism of gcd gene, which could improve the scope of PSB strains' application. PMID:26573634

  2. SD 1313-0019: Another Second-generation Star with [Fe/H] = -5.0, Observed with the Magellan Telescope

    NASA Astrophysics Data System (ADS)

    Frebel, Anna; Chiti, Anirudh; Ji, Alexander P.; Jacobson, Heather R.; Placco, Vinicius M.

    2015-09-01

    We present a Magellan/MIKE high-resolution (R ˜ 35,000) spectrum of the ancient star SD 1313-0019, which has an iron abundance of {{[Fe/H]}}=-5.0, paired with a carbon enhancement of {{[C/Fe]}}˜ 3.0. The star was initially identified by Allende Prieto et al. in the BOSS survey. Its medium-resolution spectrum suggested a higher metallicity of {{[Fe/H]}}=-4.3 due to the Ca ii K line blending with a CH feature, which is a common issue related to the search for the most iron-poor stars. This star joins several other similar stars with {{[Fe/H]}}≲ -5.0 that all display a combination of low-iron and high-carbon abundances. Other elemental abundances of SD 1313-0019 follow that of more metal-rich halo stars. Fitting the abundance pattern with yields of Population III supernovae suggests that SD 1313-0019 had only one massive progenitor star with 20-30 {M}⊙ that must have undergone a mixing and fallback episode. Overall, there are now five stars known with {{[Fe/H]}}≲ -5.0 (1D local thermodynamic equilibrium abundances). This ever-increasing population of carbon-rich, iron-deficient stars can potentially constrain nucleosynthesis in Population III stars and their supernova explosions, the formation mechanisms of the first low-mass stars, and the nature of the first galaxies. This paper includes data gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile.

  3. Development of quercetin-phospholipid complex to improve the bioavailability and protection effects against carbon tetrachloride-induced hepatotoxicity in SD rats.

    PubMed

    Zhang, Kexia; Zhang, Meiyu; Liu, Ziying; Zhang, Yuanyuan; Gu, Liqiang; Hu, Gaosheng; Chen, Xiaohui; Jia, Jingming

    2016-09-01

    Quercetin (QT) is a natural flavonoid with various biological activities and pharmacological actions. However, the bioavailability of QT is relatively low due to its low solubility which severely limits its use. In this study, we intended to improve the bioavailability of QT by preparing quercetin-phospholipid complex (QT-PC) and investigate the protective effect of QT-PC against carbon tetrachloride (CCl4) induced acute liver damage in Sprague-Dawley (SD) rats. The physicochemical properties of QT-PC were characterized in terms of infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), powder X-ray diffraction (XRPD) and water/n-octanol solubility. FTIR, DSC and XRPD data confirmed the formation of QT-PC. The water solubility of QT was improved significantly in the prepared complex, indicating its increased hydrophilicity. Oral bioavailability of QT and QT-PC was evaluated in SD rats, and the plasma QT was estimated by HPLC-MS. QT-PC exhibited higher Cmax (1.58±0.11 vs. 0.67±0.08μg/mL), increased AUC0-∞ (8.60±1.25 vs. 2.41±0.51mg/Lh) and t1/2z (7.76±1.09 vs. 4.81±0.87h) when compared to free QT. The greater absorption of QT-PC group suggested the improved bioavailability. Moreover, biochemical changes and histopathological observations revealed that QT-PC provided better protection to rat liver than free QT at the same dose. Thus, phospholipid complexation might be one of the suitable approaches to improve the oral bioavailability of QT and obtain better protective effects against CCl4 induced acute liver damage in SD rats than free QT at the same dose level. PMID:27431774

  4. References for HNF-SD-WM-TRD-007, ``System specification for the double-shell tank system: HNF-PROs, CFRs, DOE Orders, WACs``

    SciTech Connect

    Shaw, C.P.

    1998-07-30

    HNF-SD-WM-TRD-O07, System Specification for the Double-Shell Tank System, (hereafter referred to as DST Specification), defines the requirements of the double-shell tank system at the Hanford Site for Phase 1 privatization. Many of the sections in this document reference other documents for design guidance and requirements. Referenced documents include Project Hanford Management Contract (PHMC) procedures (HNF-PROS), Codes of Federal Regulation (CFRs), DOE Orders, and Washington Administrative Codes (WACs). This document provides rationale for the selection and inclusion of HNF-PROS, CFRs, DOE Orders and WACs.

  5. Crystal structures of RPt{sub 3-x}Si{sub 1-y}(R=Y, Tb, Dy, Ho, Er, Tm, Yb) studied by single crystal X-ray diffraction

    SciTech Connect

    Gribanov, Alexander; Grytsiv, Andriy; Rogl, Peter; Seropegin, Yurii; Giester, Gerald

    2009-07-15

    The crystal structures of ternary compounds RPt{sub 3-x}Si{sub 1-y}(R=Y, Tb, Dy, Ho, Er, Tm, Yb) have been elucidated from X-ray single crystal CCD data. All compounds are isotypic and crystallize in the tetragonal space group P4/mbm. The general formula RPt{sub 3-x}Si{sub 1-y} arises from defects: x{approx}0.20, y{approx}0.14. The crystal structure of RPt{sub 3-x}Si{sub 1-y} can be considered as a packing of four types of building blocks which derive from the CePt{sub 3}B-type unit cell by various degrees of distortion and Pt, Si-defects. - Graphical Abstract: Electron density in RPt{sub 3-x}Si{sub 1-y} at 0, 1/2 , 0.

  6. Preparation and electrochemical magnesium insertion behaviors of Mg 0.5+ y(Me yTi 1- y) 2(PO 4) 3 (Me = Cr, Fe)

    NASA Astrophysics Data System (ADS)

    Makino, Koji; Katayama, Yasushi; Miura, Takashi; Kishi, Tomiya

    A series of transition metal phosphates, Mg 0.5+ y(Fe yTi 1- y) 2(PO 4) 3 (MFTP) and Mg 0.5+ y(Cr yTi 1- y) 2(PO 4) 3 (MCTP), modified from Mg 0.5Ti 2(PO 4) 3 (MTP) were prepared by sol-gel method and evaluated as a possible cathode material for magnesium cells. The lattice structures of MFTP and MCTP at 0≤ y≤0.5 were identical with that of MTP, while their unit cell volumes were smaller than that of MTP due to the increased amount of Mg 2+ ions. Electrochemical magnesium insertion into MFTP and MCTP was found to be possible as observed for MTP. However, the limiting extent of magnesium insertion into MFTP at 0.1≤ y≤0.5 was small compared with MTP and remarkably dependent on the discharge current density during discharge. These facts suggested that the insertion limit is determined not by the number of available sites for Mg 2+ or electrons but by the mobility of Mg 2+ in these host materials correlating with decrease in the unit cell volume.

  7. Mn(II) Oxidation Is Catalyzed by Heme Peroxidases in “Aurantimonas manganoxydans” Strain SI85-9A1 and Erythrobacter sp. Strain SD-21▿

    PubMed Central

    Anderson, C. R.; Johnson, H. A.; Caputo, N.; Davis, R. E.; Torpey, J. W.; Tebo, B. M.

    2009-01-01

    A new type of manganese-oxidizing enzyme has been identified in two alphaproteobacteria, “Aurantimonas manganoxydans” strain SI85-9A1 and Erythrobacter sp. strain SD-21. These proteins were identified by tandem mass spectrometry of manganese-oxidizing bands visualized by native polyacrylamide gel electrophoresis in-gel activity assays and fast protein liquid chromatography-purified proteins. Proteins of both alphaproteobacteria contain animal heme peroxidase and hemolysin-type calcium binding domains, with the 350-kDa active Mn-oxidizing protein of A. manganoxydans containing stainable heme. The addition of both Ca2+ ions and H2O2 to the enriched protein from Aurantimonas increased manganese oxidation activity 5.9-fold, and the highest activity recorded was 700 μM min−1 mg−1. Mn(II) is oxidized to Mn(IV) via an Mn(III) intermediate, which is consistent with known manganese peroxidase activity in fungi. The Mn-oxidizing protein in Erythrobacter sp. strain SD-21 is 225 kDa and contains only one peroxidase domain with strong homology to the first 2,000 amino acids of the peroxidase protein from A. manganoxydans. The heme peroxidase has tentatively been named MopA (manganese-oxidizing peroxidase) and sheds new light on the molecular mechanism of Mn oxidation in prokaryotes. PMID:19411418

  8. Single oral dose toxicity test of polycalcium, a mixed composition of polycan and calcium lactate-gluconate 1:9 (G/G) in SD rat.

    PubMed

    Kim, Joo-Wan; Choi, Jae-Suk; Ha, Yu-Mi; Choi, In Soon; Kim, Ki-Young; Cho, Hyung-rae; Rha, Chae-hun; Ku, Sae-Kwang

    2013-11-01

    The object of this study was to obtain acute oral toxicity information of Polycalcium, a mixed composition of Polycan and Calcium lactate-gluconate 1:9 (g/g), in Sprague-Dawely (SD) rats. In order to investigate the toxicity and identify target organs, Polycalcium were once orally administered to female and male SD rats at dose levels of 2000, 1000, 500 and 0 (control) mg/kg body weights. The mortality, changes on body weight and clinical signs were monitored during 14 days after treatment with gross observation, changes on the organ weights and histopathology of principle organs and treatment sites based on the recommendation of KFDA Guidelines [2009-116, 2009]. As the results of single oral treatment of Polycalcium, no treatment related mortalities were observed within 14 days after end of treatment up to 2000 mg/kg, the limited dosage of rodents in the both genders. In addition, no Polycalcium treatment related changes on the body and organ weights, clinical signs, necropsy and histopathological findings were detected. The results obtained in this study suggest that the Polycalcium is non-toxic in rats. The LD50 and approximate LD in rats after single oral dose of Polycalcium were considered over 2000 mg/kg in both female and male, respectively. PMID:24191319

  9. Vibrational relaxation dynamics of SD molecules in As{sub 2}S{sub 3}: Observation of an anomalous isotope effect

    SciTech Connect

    Engholm, J.R.; Happek, U.; Rella, C.W.

    1995-12-31

    It is generally assumed that the vibrational relaxation of molecular impurities in crystals and glasses mainly depends on the order of the decay process, with lower order processes leading to more rapid relaxation (a behavior that is known under the term {open_quotes}gap-law{close_quotes}). Here we present measurements that contradict this assumption. Using high intensity psec pulses of the Stanford FEL we measured the relaxation rate of the SD vibrational stretch mode (at a frequency of 1800 cm) by applying a pump-probe technique. We find relaxation rates on the order of 2x10{sup 9} sec{sup -1}, which are a factor of 2 lower than those found for the isotope molecule SH (at a frequency of about 2500 cm{sup - 1}) in the same host{sup 1}. We recall that the relaxation of the SD vibrational stretch mode is controlled by a lower order process as compared to the SH molecule, which is due to the smaller number of host vibrational quanta to match the energy of the stretch mode; a fact we have confirmed experimentally by temperature dependent relaxation measurements. Thus our remits are in marked contrast to the so-called {open_quotes}Gap-Law{close_quotes} and emphasize the importance of the molecule - host coupling in the relaxation dynamics.

  10. Analysis of helium-rich subdwarf O stars. 1: NLTE models, methods, and fits for 21 Palomar Green survey sdOs

    NASA Technical Reports Server (NTRS)

    Thejll, P.; Bauer, F.; Saffer, R.; Liebert, J.; Kunze, D.; Shipman, H. L.

    1994-01-01

    Atmospheric parameters for 21 helium-rich hot subdwarf O stars from the Palomar Green survey are found from fits of non-local thermodynamic equilibrium (NLTE) models to optical spectra. About 250 new NLTE models in the parameter range T(sub eff) from 35,000 to 65,000 K, log (g) from 4.0 to 6.5, and epsilon(He) from 50% He to 99% He have been calculated. A fit for each object is presented. Estimated distances and luminosities are calculated, assuming a mass of 0.5 solar masses. Large distances above the Galactic plane are found, and this implies that the majority of the sdO stars belong to a different stellar population than the sdB, planetary nebulae and white dwarf stars. Possibilities may include the halo and a 'thick disk.' Kinematical data from the literature are also discussed in view of the found distances. Five of the stars have been observed, modeled, and analyzed by Dreizler et al., and significant differences exist between their results and ours for these stars. The reason for these differences is not yet known, but the problem does not alter the conclusions about population membership that we present.

  11. THE ROMER DELAY AND MASS RATIO OF THE sdB+dM BINARY 2M 1938+4603 FROM KEPLER ECLIPSE TIMINGS

    SciTech Connect

    Barlow, Brad N.; Wade, Richard A.; Liss, Sandra E.

    2012-07-10

    The eclipsing binary system 2M 1938+4603 consists of a pulsating hot subdwarf B star and a cool M dwarf companion in an effectively circular three-hour orbit. The light curve shows both primary and secondary eclipses, along with a strong reflection effect from the cool companion. Here, we present constraints on the component masses and eccentricity derived from the Romer delay of the secondary eclipse. Using six months of publicly available Kepler photometry obtained in short-cadence mode, we fit model profiles to the primary and secondary eclipses to measure their centroid values. We find that the secondary eclipse arrives on average 2.06 {+-} 0.12 s after the midpoint between primary eclipses. Under the assumption of a circular orbit, we calculate from this time delay a mass ratio of q = 0.2691 {+-} 0.0018 and individual masses of M{sub sd} = 0.372 {+-} 0.024 M{sub Sun} and M{sub c} = 0.1002 {+-} 0.0065 M{sub Sun} for the sdB and M dwarf, respectively. These results differ slightly from those of a previously published light-curve modeling solution; this difference, however, may be reconciled with a very small eccentricity, ecos {omega} Almost-Equal-To 0.00004. We also report a decrease in the orbital period of P-dot = (-1.23 {+-} 0.07) Multiplication-Sign 10{sup -10}.

  12. Chemistry and dynamics of the secondary ozone layer during the sudden stratospheric warming in the southern hemisphere in 2002, using WACCM-SD

    NASA Astrophysics Data System (ADS)

    Smith-Johnsen, Christine; Limpasuvan, Varavut; Yvan, Orsolini; Frode, Stordal

    2015-04-01

    A sudden stratospheric warming (SSW) will affect the chemistry and dynamics of the middle atmosphere, and up to the thermosphere. The major warmings occur roughly every other year in the northern hemispheric winter, but has only been observed once in the southern hemisphere, during the antarctic winter of 2002. In this paper we will investigate the effects of the 2002 southern hemispheric warming on the upper atmosphere, by using the National Centre for Atmospheric Research's Whole Atmosphere Community Climate Model with specified dynamics (WACCM-SD). The secondary ozone layer at around 90km altitude will be the focus, and chemical compounds such as hydrogen, oxygen, carbon monoxide and nitric oxide will be studied as well as the temperature and zonal, meridional and vertical winds, all outputs from WACCM-SD. Three reductions of the zonal mean zonal wind occurs before the final reversal from westerlies to easterlies winds defines the onset of the SSW. At about the same time, at 90 km altitude, an increase of O3 can be seen, and a decrease of NOX, O, CO, H and temperature.

  13. Non-radiative recombination in Ge1-ySny light emitting diodes: The role of strain relaxation in tuned heterostructure designs

    NASA Astrophysics Data System (ADS)

    Gallagher, J. D.; Senaratne, C. L.; Xu, C.; Sims, P.; Aoki, T.; Smith, D. J.; Menéndez, J.; Kouvetakis, J.

    2015-06-01

    This paper describes the properties of Ge1-ySny light emitting diodes with a broad range of Sn concentrations (y = 0.0-0.11). The devices are grown upon Si(100) platforms using ultra-low temperature deposition of highly reactive Ge and Sn hydrides. The device fabrication adopts two new photodiode designs which lead to optimized performance and enables a systematic study of the effects of strain relaxation on emission efficiency. In contrast with n-Ge/i-Ge1-ySny/p-Ge analogs, which in most cases contain two defected interfaces, our designs include a p-layer with composition Ge1-zSnz chosen to be z < y to facilitate light extraction, but with z close enough to y to guarantee no strain relaxation at the i/p interface. In addition, a Ge1-xSnx alloy is also used for the n layer, with compositions in the 0 ≤ x ≤ y range, so that defected and non-defected n/i interfaces can be studied. The electroluminescence spectra vs the Sn content y in the intrinsic layer of the diodes exhibit a monotonic shift in the emission wavelength from 1550 nm to 2500 nm. On the other hand, the emission intensities show a complex dependence that cannot be explained solely on the basis of Sn concentrations. Detailed theoretical modeling of these intensities makes it possible to extract recombination lifetimes that are found to be more than three times longer in samples in which strain relaxation has not occurred at the n-i interface, demonstrating the existence of a large non-radiative contribution from the relaxation defects. This finding is particularly significant for direct gap diodes with y > 0.09, for which it is practically impossible to avoid strain relaxation in n-Ge/i-Ge1-ySny/p-Ge analogs. The new designs introduced here open the door to the fabrication of highly efficient electrically pumped systems for applications in future generations of integrated photonics.

  14. Oncosuppressive Suicide Gene Virotherapy “PVH1-yCD/5-FC” for Pancreatic Peritoneal Carcinomatosis Treatment: NFκB and Akt/PI3K Involvement

    PubMed Central

    Réjiba, Soukaina; Bigand, Christelle; Parmentier, Celine; Masmoudi, Ahmed; Hajri, Amor

    2013-01-01

    Peritoneal carcinomatosis is common in advanced pancreatic cancer. Despite current standard treatment, patients with this disease until recently were considered incurable. Cancer gene therapy using oncolytic viruses have generated much interest over the past few years. Here, we investigated a new gene directed enzyme prodrug therapy (GDEPT) approach for an oncosuppressive virotherapy strategy using parvovirus H1 (PV-H1) which preferentially replicates and kills malignant cells. Although, PV-H1 is not potent enough to destroy tumors, it represents an attractive vector for cancer gene therapy. We therefore sought to determine whether the suicide gene/prodrug system, yCD/5-FC could be rationally combined to PV-H1 augmenting its intrinsic oncolytic activity for pancreatic cancer prevention and treatment. We showed that the engineered recombinant parvovirus rPVH1-yCD with 5-FC treatment increased significantly the intrinsic cytotoxic effect and resulted in potent induction of apoptosis and tumor growth inhibition in chemosensitive and chemoresistant cells. Additionally, the suicide gene-expressing PV-H1 infection reduced significantly the constitutive activities of NFκB and Akt/PI3K. Combination of their pharmacological inhibitors (MG132 and LY294002) with rPVH1-yCD/5-FC resulted in substantial increase of antitumor activity. In vivo, high and sustained expression of NS1 and yCD was observed in the disseminated tumor nodules and absent in normal tissues. Treatment of mice bearing intraperitoneal pancreatic carcinomatosis with rPVH1-yCD/5-FC resulted in a drastic inhibition of tumor cell spreading and subsequent increase in long-term survival. Together, the presented data show the improved oncolytic activity of wPV-H1 by yCD/5-FC and thus provides valuable effective and promising virotherapy strategy for prevention of tumor recurrence and treatment. In the light of this study, the suicide gene parvovirotherapy approach represents a new weapon in the war against

  15. Photoluminescence study of {InxGa1-xAs}/{InyAl1-yAs} one-side-modulation-doped asymmetric step quantum wells

    NASA Astrophysics Data System (ADS)

    Li, Hanxuan; Wang, Zhanguo; Liang, Jiben; Xu, Bo; Jiang, Chao; Gong, Qian; Liu, Fengqi; Zhou, Wei

    1998-06-01

    Fourier transform photoluminescence measurements were carried out to investigate the optical transitions in {InxGa1-xAs}/{InyAl1-yAs} one-side-modulation-doped asymmetric step quantum wells. Samples with electron density ns between 0.8 and 5.3 × 10 12cm -2 are studied. Strong recombination involving one to three populated electron subbands with the first heavyhole subband is observed. Fermi edge singularity (FES) clearly can be observed for some samples. The electron subband energies in the {InGaAs}/{InAlAs} step quantum wells were calculated by a self-consistent method, taking into account strain and nonparabolicity effects and the comparison with the experimental data shows a good agreement. Our results can help improve understanding for the application of {InGaAs}/{InAlAs} step quantum wells in microelectronic and optoelectronic devices.

  16. Processing & properties La{sub 1-x}A{sub x}Co{sub 1-y}Fe{sub y}O{sub 3}(A = Sr, Ca) perovskites

    SciTech Connect

    Stevenson, J.W.; Armstrong, T.R.; Pederson, L.R.

    1995-04-01

    Selected compositions within the system La{sub 1-x}A{sub x}Co{sub 1-y}Fe{sub y}O{sub 3-{delta}}(A = Sr, Ca) were prepared by combustion synthesis and characterized by XRD, TGA, electrical conductivity, and oxygen permeation measurements. Substantial weight loss (due to loss of lattice oxygen) was observed in some compositions at high temperatures. For Sr containing materials, this weight loss increased with increasing Sr content. A substantial decrease in electronic conductivity was observed at high temperatures in Sr doped materials; this decrease was related to the decreased oxygen stoichiometry at these temperatures. In Sr doped compositions, oxygen flux increased with increasing Sr content. Calculated values of ionic conductivity were greater than the conductivity of yttria stabilized zirconia. Substitution of Ca for Sr resulted in substantially lower fluxes.

  17. Time resolved photoluminescence spectroscopy of narrow gap Hg1-xCdxTe/CdyHg1-yTe quantum well heterostructures

    NASA Astrophysics Data System (ADS)

    Morozov, S. V.; Rumyantsev, V. V.; Antonov, A. V.; Kadykov, A. M.; Maremyanin, K. V.; Kudryavtsev, K. E.; Mikhailov, N. N.; Dvoretskii, S. A.; Gavrilenko, V. I.

    2014-07-01

    Photoluminescence (PL) spectra and kinetics of narrow gap Hg1-xCdxTe/CdyHg1-yTe quantum well (QW) heterostructures grown by molecular beam epitaxy technique are studied. Interband PL spectra are observed from 18 K up to the room temperature. Time resolved studies reveal an additional PL line with slow kinetics (7 μs at 18 K) related to deep defect states in barrier layers. These states act as traps counteracting carrier injection into QWs. The decay time of PL signal from QW layers is about 5 μs showing that gain can be achieved at wavelengths 10-20 μm by placing such QWs in HgCdTe structures with waveguides.

  18. Evolution of photoinduced effects in phase-separated Sm0.5Sr0.5Mn1-yCryO3 thin films.

    PubMed

    Chai, Xiaojie; Xing, Hui; Jin, Kexin

    2016-01-01

    Systematic study on electrical transport properties has been performed in Sm0.5Sr0.5Mn1-yCryO3 thin films illuminated by the light. An evolution of persistent and transient photoinduced effects induced by the impurity doping and temperature has been observed, which is closely related to the number of ferromagnetic clusters. The maximum persistent photoinduced effect is observed at y = 0.08 and the corresponding value is about 61.7% at the power density of 13.7 mW/mm(2). The underlying mechanism can be understood by the coexistence and competition of the multiphases in phase-separated manganites induced by Cr-doping. These results would pave the way for practical applications in innovative photoelectric devices of all-oxides. PMID:27001006

  19. Distributed Bragg reflector lattice-matched Pb/sub 1-x/Sn/sub x/Te/PbSe/sub y/Te/sub 1-y/ diode lasers

    SciTech Connect

    Kapon, E.; Zussman, A.; Katzir, A.

    1984-02-01

    Distributed Bragg reflector (DBR) lattice-matched Pb/sub 1-x/Sn/sub x/Te/PbSe/sub y/Te/sub 1-y/ diode lasers were fabricated using liquid phase epitaxy. These DBR lasers were operated within a limited range of heat-sink temperatures 8.5--38 K, and the threshold current density at 20 K was approx.3 kA/cm/sup 2/. Single longitudinal-mode operation was obtained up to more than three times the threshold current. The DBR lasers exhibited continuous tuning over a relatively wide range of approx.6 cm/sup -1/ near 775 cm/sup -1/ (12.9 ..mu..m). The average tuning rate was 0.21 cm/sup -1//K, and it was much smaller than the rate for corresponding Fabry--Perot lasers, which was 2.3 cm/sup -1//K.

  20. Comparison between experimental and theoretical determination of the local structure of the GaAs1-yNy dilute nitride alloy

    NASA Astrophysics Data System (ADS)

    Ciatto, Gianluca; D'Acapito, Francesco; Sanna, Simone; Fiorentini, Vincenzo; Polimeni, Antonio; Capizzi, Mario; Mobilio, Settimio; Boscherini, Federico

    2005-03-01

    We present a combined experimental and theoretical study of the local structure of the GaAs1-yNy dilute nitride alloy. Experimental results obtained by x-ray absorption spectroscopy have been compared with first-principles density-functional supercell calculations and with the predictions of three different valence force field models. Both experiments and calculations find that inclusion of N induces static disorder in the Ga-As bond length distribution. An increase of the Ga-As bond length upon N incorporation in gallium arsenide has been observed; this is due to the competing effects of the decrease of the free lattice parameter and the tensile strain due to pseudomorphic growth. The different theoretical calculations reproduce more or less accurately this bond length expansion; we discuss the performance of the different valence force field models in predicting the measured bond lengths.

  1. Nonlinear structure-composition relationships in the Ge1-ySny/Si(100) (y<0.15) system

    SciTech Connect

    Beeler, R.; Roucka, R.; Chizmeshya, A. V. G.; Kouvetakis, J.; Menéndez, J.

    2011-07-26

    The compositional dependence of the cubic lattice parameter in Ge1-ySny alloys has been revisited. Large 1000-atom supercell ab initio simulations confirm earlier theoretical predictions that indicate a positive quadratic deviation from Vegard's law, albeit with a somewhat smaller bowing coefficient, θ = 0.047 Å, than found from 64-atom cell simulations (θ = 0.063 Å). On the other hand, measurements from an extensive set of alloy samples with compositions y < 0.15 reveal a negative deviation from Vegard's law. The discrepancy with earlier experimental data, which supported the theoretical results, is traced back to an unexpected compositional dependence of the residual strain after growth on Si substrates. The experimental bowing parameter for the relaxed lattice constant of the alloys is found to be θ = -0.066 Å. Possible reasons for the disagreement between theory and experiment are discussed in detail.

  2. The recombination velocity at III-V compound heterojunctions with applications to Al (x) Ga(1-x)As-GaAs(1-y)Sb(y)

    NASA Technical Reports Server (NTRS)

    Kim, J. S.

    1978-01-01

    Interface recombination velocity in AlxGa1-xAs-GaAs and A10.85 Ga0.15As-GaAs1-ySby heterojunction systems was studied as a function of lattice mismatch. The results are applied to the design of highly efficient III-V heterojunction solar cells. A horizontal liquid-phase epitaxial growth system was used to prepare p-p-p and p-p-n double heterojunction test samples with specified values of x and y. Samples were grown at each composition, with different GaAs and GaAsSb layer thicknesses. A method was developed to obtain the lattice mismatch and lattice constants in mixed single crystals grown on (100) and (111)B oriented GaAs substrates.

  3. Room-temperature oxidation of hypostoichiometric uranium-plutonium mixed oxides U1-yPuyO2-x - A depth-selective approach

    NASA Astrophysics Data System (ADS)

    Vauchy, Romain; Robisson, Anne-Charlotte; Belin, Renaud C.; Martin, Philippe M.; Scheinost, Andreas C.; Hodaj, Fiqiri

    2015-10-01

    In the present work, TGA, XAS and XRD were used to evidence the spontaneous oxidation of biphasic U1-yPuyO2-x samples, with y = 0.28 and 0.45, at room temperature and upon exposure to low moisture and oxygen contents. The oxidation occurs within very short timescales (e.g. O/M ratio increasing from 1.94 to 1.98 within ∼1 μm surface layer in ∼50 h). The combined use of these three complementary methods offered a depth-selective approach from the sample's bulk to its surface and allowed a thorough understanding of the underlying processes involved during the formation of the oxidized layer and of its thickening with time. We believe our results to be of interest in the prospect of fabricating hypo-stoichiometric uranium-plutonium mixed oxides since mastering the oxygen content is a crucial point for many of the fuel properties.

  4. Calculation of the Ti(C y N1- y )-Ti4C2S2-MnS-austenite equilibrium in Ti-bearing steels

    NASA Astrophysics Data System (ADS)

    Liu, W. J.; Jonas, J. J.

    1989-08-01

    A thermodynamic model is presented for the equilibria among various precipitates (Ti(C y N1- y ), Ti4C2S2, and MnS) and austenite containing six alloying elements (C, Mn, N, S, Si, and Ti). This model is applied to four microalloyed steels with Ti levels of 0.05, 0.11, 0.18, and 0.25 pct. The calculations show that the Ti in these steels cannot be completely dissolved over the austenite temperature range. However, the compositions of the undissolved Ti carbonitrides differ significantly from pure TiN, as 10 to 40 pct of the nitrogen is replaced by carbon. An expression for the Gibbs energy for the formation of Ti4C2S2 in austenite is estimated. The present predictions are compared with those of the Hudd, Jones, and Kale (HJK) model; considerable differences are observed at temperatures below 1250°C.

  5. Intrinsic Josephson properties in Pb1-ySr2Y1-xCaxCu2+yO7+δ epitaxial films

    NASA Astrophysics Data System (ADS)

    Komori, Sachio; Kakeya, Itsuhiro

    2014-12-01

    We report the first observation of intrinsic Josephson junction (IJJ) characteristics in the Pb1-ySr2Y1-xCaxCu2+yO7+δ (Pb1212) epitaxial film. Pb1212 epitaxial film has been grown on SrTiO3 (100) substrates by a two-step growth technique. A small mesa structure (S = 4μm2) has been fabricated on a film surface using a standard photolithography and an Ar ion milling technique. The superconducting transition temperature of the IJJ is 43 K. At 4.2 K, the value of Jc (the critical current density) is 2.2 kA/cm2. The depth of the hysteresis defined as α = (Jc+Jr)/ Jc is 0.89, where Jr is the return current density. The temperature dependence of Jc shows good agreement with Ambegaokar-Baratoff theory.

  6. Infectivity, Pathogenicity, and Virulence of Trypanosoma cruzi Isolates from Sylvatic Animals and Vectors, and Domestic Dogs from the United States in ICR Strain Mice and SD Strain Rats

    PubMed Central

    Roellig, Dawn M.; Yabsley, Michael J.

    2010-01-01

    Trypanosoma cruzi, the causative agent of Chagas disease, is widespread in the southern United States. In addition to detection in numerous wildlife host species, cases have been diagnosed in domestic dogs and humans. In the current investigation, groups of laboratory mice [Crl:CD1 (ICR)] were inoculated with one of 18 United States T. cruzi isolates obtained from a wide host range to elucidate their infectivity, pathogenicity, and virulence. In addition, laboratory rats (SD strain) were inoculated with four isolates. Mice and rats were susceptible to infection with all strains, but no morbidity or mortality was noted, which indicates that these T. cruzi isolates from the United States had low virulence for laboratory mice and rats. PMID:20810814

  7. Mechanical properties of fractures from drillholes, UE25-NRG-4; USW-NRG-6; USW-NRG-7; USW-SD-9, at Yucca Mountain, Nevada

    SciTech Connect

    Olsson, W.A.; Brown, S.R.

    1997-01-01

    Rock cores from drillholes UE25-NRG-4, USW-NRG-6, USW-NRG-7, and USW-SD-9 containing natural fractures were obtained from the Sample Management Facility at Yucca Mountain, Nevada. All recoverable fractures were sheared at constant normal stresses from 2.5 to 15 MPa, in the as-received condition (air-dry). Detailed profilometer data were collected from each fracture surface before testing. The tests yielded the normal closure as a function of normal stress, and the shear stress and dilation as functions of shear offset. The constitutive properties obtained from these stress-displacement relations were: normal stiffness, shear stiffness, shear strength, and dilation angle at peak shear stress. Shear strength plotted against normal stress for four thermomechanical units shows that friction angle varies from 370 to 460 and cohesion varies from 0.02 to 1.71 MPa.

  8. B{sub s(d)}-B{sub s(d)} mixing constraints on flavor changing decays of t and b quarks

    SciTech Connect

    Faessler, Amand; Gutsche, Thomas; Lyubovitskij, Valery E.; Kovalenko, Sergey; Schmidt, Ivan

    2010-10-01

    We study those dimension 6 effective operators which generate flavor-changing quark-gluon transitions of the third generation quarks, with t{yields}g+u(c) and b{yields}g+d(s), and which could be of interest for LHC experiments. We analyze the contribution of these operators to B{sub s(d)}-B{sub s(d)} mixing and derive limits on the corresponding effective couplings from the existing experimental data. The standard model gauge invariance relates these couplings to the couplings controlling t{yields}g+u(c). On this basis we derive upper limits for the branching ratios of these processes. We further show that forthcoming LHC experiments might be able to probe the studied operators and the physics beyond the standard model related to them.

  9. Aspewentins D-H, 20-Nor-isopimarane Derivatives from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310.

    PubMed

    Li, Xiao-Dong; Li, Xiao-Ming; Li, Xin; Xu, Gang-Ming; Liu, Yang; Wang, Bin-Gui

    2016-05-27

    Five new 20-nor-isopimarane diterpenoids, aspewentins D-H (1-5), along with a related known congener, aspewentin A (6), were isolated from the culture extract of Aspergillus wentii SD-310, a fungal strain obtained from a deep-sea sediment sample. The structures of these compounds were established on the basis of spectroscopic interpretation, and the absolute configurations of compounds 1-5 were determined by X-ray crystallographic analysis and TDDFT-ECD calculations. The isolated compounds were evaluated for antimicrobial activity against nine human and aquatic pathogenic bacteria and four plant pathogenic fungi as well as for lethality against brine shrimp (Artemia salina). 20-Nor-isopimarane derivatives rarely occur in fungi, and only three (aspewentins A-C) have previously been reported from a marine-derived fungus. PMID:27148955

  10. Magnetic structure and its role in the possible Weyl state in topological semimetal Sr1 - yMn1 - zSb2 (0 < y , z < 0 . 1)

    NASA Astrophysics Data System (ADS)

    Zhang, Qiang; Cao, Huibo; Liu, Jinyu; Tennant, Alan; Ditusa, John; Mao, Zhiqiang

    Very recently, Liu et al (arxiv.org/pdf/1507.07978, (2015)) discovered the first magnetic topological semimetal Sr1-yMn1-zSb2(01-yMn1-zSb2, either the FM ordering at 304< T<565 K or the FM component of the canted AFM order for T<304 K, is sufficient to break time-reversal symmetry likely creating a Weyl semimetal. This work is supported by the U.S. Department of Energy under EPSCoR Grant No. DE-SC0012432 with additional support from the Louisiana Board of Regents.

  11. Cell-Type Specific Channelopathies in the Prefrontal Cortex of the fmr1-/y Mouse Model of Fragile X Syndrome1,2,3

    PubMed Central

    Johnston, Daniel; Brager, Darrin H.

    2015-01-01

    Abstract Fragile X syndrome (FXS) is caused by transcriptional silencing of the fmr1 gene resulting in the loss of fragile X mental retardation protein (FMRP) expression. FXS patients display several behavioral phenotypes associated with prefrontal cortex (PFC) dysfunction. Voltage-gated ion channels, some of which are regulated by FMRP, heavily influence PFC neuron function. Although there is evidence for brain region-specific alterations to the function a single type of ion channel in FXS, it is unclear whether subtypes of principal neurons within a brain region are affected uniformly. We tested for alterations to ion channels critical in regulating neural excitability in two subtypes of prefrontal L5 pyramidal neurons. Using somatic and dendritic patch-clamp recordings, we provide evidence that the functional expression of h-channels (Ih) is down-regulated, whereas A-type K+ channel function is up-regulated in pyramidal tract-projecting (PT) neurons in the fmr1-/y mouse PFC. This is the opposite pattern of results from published findings from hippocampus where Ih is up-regulated and A-type K+ channel function is down-regulated. Additionally, we find that somatic Kv1-mediated current is down-regulated, resulting in increased excitability of fmr1-/y PT neurons. Importantly, these h- and K+ channel differences do not extend to neighboring intratelencephalic-projecting neurons. Thus, the absence of FMRP has divergent effects on the function of individual types of ion channels not only between brain regions, but also variable effects across cell types within the same brain region. Given the importance of ion channels in regulating neural circuits, these results suggest cell-type-specific phenotypes for the disease. PMID:26601124

  12. Origin of giant piezoelectric effect in lead-free K1-xNaxTa1-yNbyO3 single crystals.

    PubMed

    Tian, Hao; Meng, Xiangda; Hu, Chengpeng; Tan, Peng; Cao, Xilong; Shi, Guang; Zhou, Zhongxiang; Zhang, Rui

    2016-01-01

    A series of high-quality, large-sized (maximum size of 16 × 16 × 32 mm(3)) K1-xNaxTa1-yNbyO3 (x = 0.61, 0.64, and 0.70 and corresponding y = 0.58, 0.60, and 0.63) single crystals were grown using the top-seed solution growth method. The segregation of the crystals, which allowed for precise control of the individual components of the crystals during growth, was investigated. The obtained crystals exhibited excellent properties without being annealed, including a low dielectric loss (0.006), a saturated hysteresis loop, a giant piezoelectric coefficient d33 (d33 = 416 pC/N, determined by the resonance method and d33(*) = 480 pC/N, measured using a piezo-d33 meter), and a large electromechanical coupling factor, k33 (k33 = 83.6%), which was comparable to that of lead zirconate titanate. The reason the piezoelectric coefficient d33 of K0.39Na0.61Ta0.42Nb0.58O3 was larger than those of the other two crystals grown was elucidated through first-principles calculations. The obtained results indicated that K1-xNaxTa1-yNbyO3 crystals can be used as a high-quality, lead-free piezoelectric material. PMID:27160075

  13. Suppression of superconductivity in La1.85Sr0.15Cu1-yNiyO4: The relevance of local lattice distortions

    NASA Astrophysics Data System (ADS)

    Haskel, D.; Stern, E. A.; Polinger, V.; Dogan, F.

    2001-02-01

    The effect of Ni substitution upon the local structure of La1.85Sr0.15Cu1-yNiyO4 is commonly neglected when addressing the Ni-induced destruction of the superconducting state at y≈0.03 and a metal-insulator transition at y≈0.05. It is also sometimes assumed that direct substitution of a dopant into the CuO2 planes has a detrimental effect on superconductivity due to in-plane lattice distortions around the dopants. We present here results from angular-dependent x-ray absorption fine structure (XAFS) measurements at the Ni, La and Sr K-edges of oriented powders of La1.85Sr0.15Cu1-yNiyO4 with y=0.01, 0.03, 0.06. A special magnetic alignment geometry allowed us to measure pure ĉ and ab̂ oriented XAFS at the Ni K-edge in identical fluorescence geometries. Both the near-edge absorption spectra (XANES) and the XAFS unequivocally show that the NiO6 octahedra are largely contracted along the c-axis, by ≈ 0.16 Å. Surprisingly, the Ni-O planar bonds and the Ni-O-Cu/Ni planar buckling angle are nearly identical to their Cu counterparts. The NiO6 octahedral contraction drives the macroscopic ĉ-axis contraction observed with Ni-doping. The local ĉ-axis strongly fluctuates, due to the different NiO6 and CuO6 octahedral configurations and the much stronger bonding of a La+3 ion than a Sr+2 ion to the O(2) apical oxygens. We discuss the relevance of these findings to the mechanisms of Tc suppresion and hole-localization by Ni dopants.

  14. Electron-capture and β-decay Rates for sd-Shell Nuclei in Stellar Environments Relevant to High-density O-Ne-Mg Cores

    NASA Astrophysics Data System (ADS)

    Suzuki, Toshio; Toki, Hiroshi; Nomoto, Ken'ichi

    2016-02-01

    Electron-capture and β-decay rates for nuclear pairs in the sd-shell are evaluated at high densities and high temperatures relevant to the final evolution of electron-degenerate O-Ne-Mg cores of stars with initial masses of 8-10 M⊙. Electron capture induces a rapid contraction of the electron-degenerate O-Ne-Mg core. The outcome of rapid contraction depends on the evolutionary changes in the central density and temperature, which are determined by the competing processes of contraction, cooling, and heating. The fate of the stars is determined by these competitions, whether they end up with electron-capture supernovae or Fe core-collapse supernovae. Since the competing processes are induced by electron capture and β-decay, the accurate weak rates are crucially important. The rates are obtained for pairs with A = 20, 23, 24, 25, and 27 by shell-model calculations in the sd-shell with the USDB Hamiltonian. Effects of Coulomb corrections on the rates are evaluated. The rates for pairs with A = 23 and 25 are important for nuclear Urca processes that determine the cooling rate of the O-Ne-Mg core, while those for pairs with A = 20 and 24 are important for the core contraction and heat generation rates in the core. We provide these nuclear rates at stellar environments in tables with fine enough meshes at various densities and temperatures for studies of astrophysical processes sensitive to the rates. In particular, the accurate rate tables are crucially important for the final fates of not only O-Ne-Mg cores but also a wider range of stars, such as C-O cores of lower-mass stars.

  15. Expression of angiostatin cDNA in human gallbladder carcinoma cell line GBC-SD and its effect on endothelial proliferation and growth

    PubMed Central

    Yang, Ding-Zhong; He, Jing; Zhang, Ji-Cheng; Wang, Zuo-Ren

    2006-01-01

    AIM: To explore the influence of angiostatin up-regulation on the biologic behavior of gallbladder carcinoma cells in vitro and in vitro, and the potential value of angiostatin gene therapy for gallbladder carcinoma. METHODS: A eukaryotic expression vector of pcDNA3.1(+) containing murine angiostatin was constructed and identified by restriction endonuclease digestion and sequencing. The recombinant vector pcDNA3.1-angiostatin was transfected into human gallbladder carcinoma cell line GBC-SD with Lipofectamine 2000, and paralleled with the vector and mock control. The resistant clone was screened by G418 filtration. Angiostatin transcription and protein expression were examined by RT-PCR, immunofluorescence and Western-blot. The supernatant was collected to treat endothelial cells. Cell proliferation and growth in vitro were observed under microscope. RESULTS: Murine angiostatin cDNA was successfully cloned into the eukaryotic expression vector pcDNA3.1 (+). After 14 d of transfection and selection with G418, macroscopic resistant cell cloning was formed in the experimental group transfected with pcDNA 3.1(+)-angiostatin and vector control. But untreated cells died in the mock control. Angiostatin was detected by RT-PCR and protein expression was detected in the experimental group by immunofluorescence and Western-blot. Cell proliferation and growth in vitro in the three groups were observed respectively under microscope. No significant difference was observed in the growth speed of GBC-SD cells between groups that were transfected with and without angiostatin. After treatment with supernatant, significant differences were observed in endothelial cell (ECV-304) growth in vitro. The cell proliferation and growth were inhibited. CONCLUSION: Angiostatin does not directly inhibit human gallbladder carcinoma cell proliferation and growth in vitro, but the secretion of angiostatin inhabits endothelial cell proliferation and growth. PMID:16718765

  16. Observations of PW activity in the MLT during SSW events using a chain of SuperDARN radars and SD-WACCM

    NASA Astrophysics Data System (ADS)

    Stray, N. H.; Orsolini, Y. J.; Espy, P. J.; Limpasuvan, V.; Hibbins, R. E.

    2015-01-01

    This study investigates the effect of Stratospheric Sudden Warmings (SSWs) on Planetary Wave (PW) activity in the Mesosphere-Lower Thermosphere (MLT). PW activity near 95 km is derived from meteor wind data using a chain of 8 SuperDARN radars at high northern latitudes that span longitudes from 150° W to 25° E and latitudes from 51 to 66° N. Zonal wave number 1 and 2 components were extracted from the meridional wind for the years 2000-2008. The observed wintertime PW activity shows common features associated with the stratospheric wind reversals and the accompanying stratospheric warming events. Onset dates for seven SSW events accompanied by an elevated stratopause (ES) were identified during this time period using the Specified Dynamics Whole Atmosphere Community Climate Model (SD-WACCM). For the seven events, a significant enhancement in wave number 1 and 2 PW amplitudes near 95 km was found to occur after the wind reversed at 50 km, with amplitudes maximizing approximately 5 days after the onset of the wind reversal. This PW enhancement in the MLT after the event was confirmed using SD-WACCM. When all cases of polar cap wind reversals at 50 km were considered, a significant, albeit moderate, correlation of 0.4 was found between PW amplitudes near 95 km and westward polar-cap stratospheric winds at 50 km, with the maximum correlation occurring ~3 days after the maximum westward wind. These results indicate that the enhancement of PW amplitudes near 95 km are a common feature of SSWs irrespective of the strength of the wind reversal.

  17. Rapid, Accurate, and Non-Invasive Measurement of Zebrafish Axial Length and Other Eye Dimensions Using SD-OCT Allows Longitudinal Analysis of Myopia and Emmetropization

    PubMed Central

    Collery, Ross F.; Veth, Kerry N.; Dubis, Adam M.; Carroll, Joseph; Link, Brian A.

    2014-01-01

    Refractive errors in vision can be caused by aberrant axial length of the eye, irregular corneal shape, or lens abnormalities. Causes of eye length overgrowth include multiple genetic loci, and visual parameters. We evaluate zebrafish as a potential animal model for studies of the genetic, cellular, and signaling basis of emmetropization and myopia. Axial length and other eye dimensions of zebrafish were measured using spectral domain-optical coherence tomography (SD-OCT). We used ocular lens and body metrics to normalize and compare eye size and relative refractive error (difference between observed retinal radial length and controls) in wild-type and lrp2 zebrafish. Zebrafish were dark-reared to assess effects of visual deprivation on eye size. Two relative measurements, ocular axial length to body length and axial length to lens diameter, were found to accurately normalize comparisons of eye sizes between different sized fish (R2 = 0.9548, R2 = 0.9921). Ray-traced focal lengths of wild-type zebrafish lenses were equal to their retinal radii, while lrp2 eyes had longer retinal radii than focal lengths. Both genetic mutation (lrp2) and environmental manipulation (dark-rearing) caused elongated eye axes. lrp2 mutants had relative refractive errors of −0.327 compared to wild-types, and dark-reared wild-type fish had relative refractive errors of −0.132 compared to light-reared siblings. Therefore, zebrafish eye anatomy (axial length, lens radius, retinal radius) can be rapidly and accurately measured by SD-OCT, facilitating longitudinal studies of regulated eye growth and emmetropization. Specifically, genes homologous to human myopia candidates may be modified, inactivated or overexpressed in zebrafish, and myopia-sensitizing conditions used to probe gene-environment interactions. Our studies provide foundation for such investigations into genetic contributions that control eye size and impact refractive errors. PMID:25334040

  18. Synthesis, crystal structure investigation and magnetism of the complex metal-rich boride series Cr{sub x}(Rh{sub 1-y}Ru{sub y}){sub 7-x}B{sub 3} (x=0.88-1; y=0-1) with Th{sub 7}Fe{sub 3}-type structure

    SciTech Connect

    Misse, Patrick R.N.; Mbarki, Mohammed; Fokwa, Boniface P.T.

    2012-08-15

    Powder samples and single crystals of the new complex boride series Cr{sub x}(Rh{sub 1-y}Ru{sub y}){sub 7-x}B{sub 3} (x=0.88-1; y=0-1) have been synthesized by arc-melting the elements under purified argon atmosphere on a water-cooled copper crucible. The products, which have metallic luster, were structurally characterized by single-crystal and powder X-ray diffraction as well as EDX measurements. Within the whole solid solution range the hexagonal Th{sub 7}Fe{sub 3} structure type (space group P6{sub 3}mc, no. 186, Z=2) was identified. Single-crystal structure refinement results indicate the presence of chromium at two sites (6c and 2b) of the available three metal Wyckoff sites, with a pronounced preference for the 6c site. An unexpected Rh/Ru site preference was found in the Ru-rich region only, leading to two different magnetic behaviors in the solid solution: The Rh-rich region shows a temperature-independent (Pauli) paramagnetism whereas an additional temperature-dependent paramagnetic component is found in the Ru-rich region. - Graphical abstract: The new complex boride series Cr{sub x}(Rh{sub 1-y}Ru{sub y}){sub 7-x}B{sub 3} (x=0.88-1; y=0-1) has been synthesized by arc melting the elements under purified argon atmosphere. Beside the 3d/4d site preference within the whole solid solution, an unexpected Rh/Ru site preference was found in the Ru-rich region only, leading to two different magnetic behaviors: The Rh-rich region shows a temperature-independent (Pauli) paramagnetism whereas an additional temperature-dependent paramagnetic component is found in the Ru-rich region. Highlights: Black-Right-Pointing-Pointer Synthesis of a new boride series fulfilling Vegard Acute-Accent s rule. Black-Right-Pointing-Pointer 3d/4d site preference. Black-Right-Pointing-Pointer Unexpected Ru/Rh site preference. Black-Right-Pointing-Pointer Rh-rich region is Pauli paramagnetic. Black-Right-Pointing-Pointer Ru-rich region is Pauli and temperature-dependent paramagnetic.

  19. Constraints on the winds of hot subdwarf stars from X-ray observations of two sdB binaries with compact companions: CD -30° 11223 and PG 1232-136

    NASA Astrophysics Data System (ADS)

    Mereghetti, S.; La Palombara, N.; Esposito, P.; Gastaldello, F.; Tiengo, A.; Heber, U.; Geier, S.; Wilms, J.

    2014-07-01

    Little observational data are available on the weak stellar winds of hot subdwarf stars of B spectral type (sdB). Close binary systems composed of an sdB star and a compact object (white dwarf, neutron star or black hole) could be detected as accretion-powered X-ray sources. The study of their X-ray emission can probe the properties of line-driven winds of sdB stars that cannot be derived directly from spectroscopy because of the low luminosity of these stars. Here we report on the first sensitive X-ray observations of two sdB binaries with compact companions. CD -30° 11223 is the sdB binary with the shortest known orbital period (1.2 h) and its companion is certainly a white dwarf. PG 1232-136 is an sdB binary considered the best candidate to host a black hole companion. We observed these stars with XMM-Newton in 2013 August for 50 ks and in 2009 July for 36 ks, respectively. None of them was detected and we derived luminosity upper limits of ˜1.5 × 1029 erg s-1 for CD -30° 11223 and ˜5 × 1029 erg s-1 for PG 1232-136. The corresponding mass-loss rate for PG 1232-136 is poorly constrained, owing to the unknown efficiency for black hole accretion. On the other hand, in the case of CD -30° 11223 we could derive, under reasonable assumptions, an upper limit of ˜3 × 10-13 M⊙ yr-1 on the wind mass-loss rate from the sdB star. This is one of the few observational constraints on the weak winds expected in this class of low-mass hot stars. We also report the results on the X-ray emission from a cluster of galaxies serendipitously discovered in the field of CD -30° 11223.

  20. Construction integrity assessment report (ETN-98-0005) S-Farm overground transfer (OGT) system valve pit 241-S-B to valve pit 241-S-D

    SciTech Connect

    HICKS, D.F.

    1999-08-12

    The S-Farm overground transfer (OGT) line will bypass the existing line(s), between valve pits 241-S-B and 241-S-D that no longer meet system requirements. The new OGT line will provide a waste transfer pipeline between these valve pits in support of saltwell pumping activities. The length of the OGT line is approximately 180 ft from pit to pit. The primary pipe is nominal 1-in. diameter stainless steel (SST) braided Ethylene-propylene Diene Monomer (EPDM) hose. The encasement pipe is a nominal 3-in., flanged, SST pipe made up of several different length pipe spool pieces (drawing H-2-829564, sh. 1 and sh. 2). The OGT line slopes from valve pit 241-S-B toward valve pit 241-S-D. At each end, the primary and encasement pipe connect to a pit entry spool piece. The pit entry spool pieces are constructed of prefabricated SST materials. These spool pieces allow for the separation of the primary and encasement pipelines after the pipes have entered the valve pits (drawing H-2-818280, sh. 2). The pit entry spool pieces also allow for leak detection of the encasement pipe at each end (drawing H-2-829564, sh. 2). The OGT encasement pipeline is supported above ground by adjustable height unistrut brackets and precast concrete bases (drawing H-2-829654, sh. 1). The pipeline is heat-traced and insulated. The heat tracing and insulation supply and retain latent heat that prevents waste solidification during transfers and provides freeze protection. The total length of the pipeline is above ground, thereby negating the need for cathodic corrosion protection. This Construction Integrity Assessment Report (CIAR) is prepared by Fluor Daniel Northwest for Numatec Hanford Corporation/Lockheed Martin Hanford Corporation, the operations contractor, and the U. S. Department of Energy, the system owner. The CIAR is intended to verify that construction was performed in accordance with the provisions of Washington Administrative Code, WAC-173-303-640 (3) (c), (e), (f) and (h).

  1. Triple-axis X-ray Reciprocal Space Mapping of In(y)Ga(1-y)As Thermophotovoltaic Diodes Grown on (100) InP Substrates

    SciTech Connect

    M Dashiell; H Ehsani; P Sander; F Newman; C Wang; Z Shellenbarger; D Donetski; N Gu; S Anikeev

    2006-02-16

    Analysis of the composition, strain-relaxation, layer-tilt, and the crystalline quality of In{sub y}Ga{sub 1-y}As/InP{sub 1-x}As{sub x} thermophotovoltaic (TPV) diodes grown by metal organic vapor phase epitaxy (MOVPE) is demonstrated using triple-axis x-ray reciprocal space mapping techniques. In{sub 0.53}Ga{sub 0.47}As (E{sub gap} = 0.74eV) n/p junction diodes are grown lattice matched (LM) to InP substrates and lattice mismatched (LMM) In{sub 0.67}Ga{sub 0.33}As (E{sub gap} = 0.6eV) TPV diodes are grown on three-step InP{sub 1-x}As{sub x} (0 < x < 0.32) buffer layers on InP substrates. X-ray reciprocal space maps about the symmetric (400) and asymmetric (533) reciprocal lattice points (RELPs) determine the in-plane and out-of-plane lattice parameters and strain of the In{sub y}Ga{sub 1-y}As TPV active layer and underlying InP{sub 1-x}As{sub x} buffers. Triple-axis x-ray rocking curves about the LMM In{sub 0.67}Ga{sub 0.33}As RELP show an order of magnitude increase of its full width at half maximum (FWHM) compared to that from the LM In{sub 0.53}Ga{sub 0.47}As (250asec vs. 30asec). Despite the significant RELP broadening the photovoltaic figure of merits show that the electronic quality of the LMM In{sub 0.67}Ga{sub 0.33}As approaches that of the lattice matched diode material. This indicates that misfit-related crystalline imperfections are not dominating the photovoltaic response of the optimized LMM In{sub 0.67}Ga{sub 0.33}As material compared with the intrinsic recombination processes and/or recombination through native point defects which would be present in both LMM and LM diode material. However, additional RELP broadening in non-optimized LMM In{sub 0.67}Ga{sub 0.33}As n/p junction diodes does correspond to significant degradation of TPV diode open circuit voltage and minority carrier lifetime demonstrating that there is correlation between x-ray FWHM and the electronic performance of the LMM TPV diodes.

  2. COPPER(1-Y)SILVER(Y)INDIUM - DISULFIDE(1-X)SELENIDE(2X) as a Prototype of the Pentenary Chalcopyrite Semiconductor Systems.

    NASA Astrophysics Data System (ADS)

    Chapman, Glenn Harrison

    The group III-V mixed alloy quarternary semiconductors, such as Ga(,(1-y))In(,y)As(,(1-x))P(,x) have been extensively employed in lattice matching different semiconducting layers (at specific bandgaps) to form heterojunction electro-optical devices. However, these cover only a limited set of direct bandgap/lattice constant combinations. The analogous pentenary alloys, consisting of the ternary chalcopyrite groups I -III-VI(,2) and II-IV-V(,2), have the potential of similar applications as they cover an even wider band/lattice range. As a prototype of such alloys, samples of the pentenary Cu(,(1 -y))Ag(,y)InS(,2(1-x))Se(,2x) have been synthesized and studied. Samples were prepared by reacting stoichimetric powder mixtures at about 900 C. X-ray diffractometry tests suggest the compounds maintained complete powder solid solubility throughout the system in the chalcopyrite crystal structure. The intrinsic conductivity type of the alloys appear to follow a trend towards n-type for silver and sulfur rich compounds, while forming p-type for copper and selenium rich materials. The bandgap of these samples were measured using cathodoluminescence techniques, which generally have some ambiguity in their resulting estimates. To generate better values of the band parameters extensive computer modeling for the emission spectra from heavily doped direct bandgap materials was done. The effect of band tails and Gaussian impurity states on the luminescence spectra was studied for changes in doping densities, temperature and carrier injection levels. Formulae were derived from these models to obtain better estimates of the bandgap and impurity activation levels. Algorithms were developed to obtain the impurity spreading energy of a tailed or Gaussian band, and the quasi-Fermi energy levels for injected current in a material with a specific band structure. Cathodoluminescence measurements were made at 300 and 77 K on the samples. As predicted by the models, it was found easier to

  3. Role of chalcogen vapor annealing in inducing bulk superconductivity in Fe1+yTe1-xSex [How does annealing in chalcogen vapor induce superconductivity in Fe1+yTe-xSex?

    SciTech Connect

    Lin, Wenzhi; Ganesh, P.; Gianfrancesco, Anthony; Berlijn, Tom; Maier, Thomas A.; Kalinin, Sergei V.; Sales, Brian C.; Pan, Minghu

    2015-02-01

    Recent investigations have shown that Fe1+yTe1-xSex can be made superconducting by annealing it in Se and O vapors. The current lore is that these chalcogen vapors induce superconductivity by removing the magnetic excess Fe atoms. To investigate this phenomenon we performed a combination of magnetic susceptibility, specific heat and transport measurements together with scanning tunneling microscopy and spectroscopy and density functional theory calculations on Fe1+yTe1-xSex treated with Te vapor. We conclude that the main role of the Te vapor is to quench the magnetic moments of the excess Fe atoms by forming FeTem (m ≥ 1) complexes. We show that the remaining FeTem complexes are still damaging to the superconductivity and therefore that their removal potentially could further improve superconductive properties in these compounds.

  4. Synthesis, crystal structure investigation and magnetism of the complex metal-rich boride series Crx(Rh1-yRuy)7-xB3 (x=0.88-1; y=0-1) with Th7Fe3-type structure

    NASA Astrophysics Data System (ADS)

    Misse, Patrick R. N.; Mbarki, Mohammed; Fokwa, Boniface P. T.

    2012-08-01

    Powder samples and single crystals of the new complex boride series Crx(Rh1-yRuy)7-xB3 (x=0.88-1; y=0-1) have been synthesized by arc-melting the elements under purified argon atmosphere on a water-cooled copper crucible. The products, which have metallic luster, were structurally characterized by single-crystal and powder X-ray diffraction as well as EDX measurements. Within the whole solid solution range the hexagonal Th7Fe3 structure type (space group P63mc, no. 186, Z=2) was identified. Single-crystal structure refinement results indicate the presence of chromium at two sites (6c and 2b) of the available three metal Wyckoff sites, with a pronounced preference for the 6c site. An unexpected Rh/Ru site preference was found in the Ru-rich region only, leading to two different magnetic behaviors in the solid solution: The Rh-rich region shows a temperature-independent (Pauli) paramagnetism whereas an additional temperature-dependent paramagnetic component is found in the Ru-rich region.

  5. The Fourier transform method and the SD-bar approach for the analytical and numerical treatment of multicenter overlap-like quantum similarity integrals

    SciTech Connect

    Safouhi, Hassan . E-mail: hassan.safouhi@ualberta.ca; Berlu, Lilian

    2006-07-20

    Molecular overlap-like quantum similarity measurements imply the evaluation of overlap integrals of two molecular electronic densities related by Dirac delta function. When the electronic densities are expanded over atomic orbitals using the usual LCAO-MO approach (linear combination of atomic orbitals), overlap-like quantum similarity integrals could be expressed in terms of four-center overlap integrals. It is shown that by introducing the Fourier transform of delta Dirac function in the integrals and using the Fourier transform approach combined with the so-called B functions, one can obtain analytic expressions of the integrals under consideration. These analytic expressions involve highly oscillatory semi-infinite spherical Bessel functions, which are the principal source of severe numerical and computational difficulties. In this work, we present a highly efficient algorithm for a fast and accurate numerical evaluation of these multicenter overlap-like quantum similarity integrals over Slater type functions. This algorithm is based on the SD-bar approach due to Safouhi. Recurrence formulae are used for a better control of the degree of accuracy and for a better stability of the algorithm. The numerical result section shows the efficiency of our algorithm, compared with the alternatives using the one-center two-range expansion method, which led to very complicated analytic expressions, the epsilon algorithm and the nonlinear D-bar transformation.

  6. A Combination of CDF and D0 limits on the branching ratio of B0(s)(d) ---> mu+ mu- decays

    SciTech Connect

    Bernhard, R.; Glenzinski, D.; Herndon, M.; Kamon, T.; Krutelyov, V.; Landsberg, G.; Lehner, F.; Lin, C.J.; Mrenna, S.; /Zurich U. /Fermilab /Wisconsin U., Madison /Texas A-M /Brown U.

    2005-08-01

    The authors combine the results of CDF and D0 searches for the rare decays B{sub s}{sup 0} {yields} {mu}{sup +}{mu}{sup -} and B{sub d}{sup 0} {yields} {mu}{sup +}{mu}{sup -}. The experiments use 364 pb{sup -1} and 300 pb{sup -1} of data respectively. The limits on the branching ratios are obtained by normalizing the estimated sensitivity to the decay B{sup +} {yields} J/{psi}K{sup +} taking into account the fragmentation ratios f{sub u}/f{sub s(d)}. The combined results exclude branching ratios of BR(B{sub s}{sup 0} {yields} {mu}{sup +}{mu}{sup -}) > 1.5 x 10{sup -7} and BR(B{sub d}{sup 0} {yields} {mu}{sup +}{mu}{sup -}) > 4.0 x 10{sup -8} at 95% confidence level. These are the most stringent limits on these decays at the present time.

  7. Time Course of the Changes in Novel Trioxane Antimalarial 99/411 Pharmacokinetics upon Antiepileptic Drugs Co-Administration in SD Rats

    PubMed Central

    Singh, Yeshwant; Kushwaha, Hari Narayan; Misra, Anamika; Hidau, Mahendra Kumar; Singh, Shio Kumar

    2014-01-01

    Objective. The study aimed to evaluate the influences of coadministration of antiepileptic drugs (AEDs) on an antimalarial candidate 99/411 pharmacokinetic (PK) profile. Method. For this, single oral dose PK drug interaction studies were conducted between 99/411 and FDA approved AEDs, namely, Phenytoin (PHT), Carbamazepine (CBZ), and Gabapentin (GB) in both male and female SD rats, to assess the coadministered and intersexual influences on 99/411 PK profile. Results. Studies revealed that there were no significant alterations in the PK profile of 99/411 upon PHT and CBZ coadministration in both male and female rats, while systemic exposure of 99/411 was significantly increased by about 80% in female rats upon GB coadministration. In terms of AUC, there was an increase from 2471 ± 586 to 4560 ± 1396 ng·h/mL. Overall, it was concluded that simultaneous administration of AEDs with 99/411 excludes the requirements for dose adjustment, additional therapeutic monitoring, contraindication to concomitant use, and/or other measures to mitigate risk, except for GB coadministration in females. These findings are further helpful to predict such interactions in humans, when potentially applied through proper allometric scaling to extrapolate the data. PMID:25383231

  8. Non-LTE analysis of extremely helium-rich stars. The hot sdO stars LSE 153, 259 and 263

    NASA Technical Reports Server (NTRS)

    Husfeld, D.; Butler, K.; Heber, U.; Drilling, J. S.

    1989-01-01

    Results of a non-LTE fine analysis based mainly on high-resolution CASPEC spectra for three extremely helium-rich sdO stars are discussed in order to explain hydrogen deficiency in single stars. High temperature (Teff = 70,000 to 75,000 K) and a position in the log Teff - log g diagram were found close to the Eddington limit. Various abundance estimates are derived for hydrogen (upper limits only), carbon, nitrogen, and magnesium. Hydrogen is reduced to less than 10 percent by number in LSE 153 and LSE 263, and to less than 5 percent in LSE 259. The hydrogen deficiency is accompanied by nitrogen- and carbon-enrichment in LSE 153 and LSE 259 only. In LSE 263, carbon is depleted by about 1 dex. Stellar masses obtained by assuming that a core mass-luminosity relation holds for these stars, were found to be in the range 0.6-0.9 solar mass, yielding luminosities log L/L:solar = 3.7-4.5. Two of the program stars (LSE 153 and 259) appear to be possible successors of the R CrB and helium B stars, whereas the third star (LSE 263) displays a much lower carbon content in its photosphere making it an exceptional case among the known hydrogen deficient stars.

  9. Anti-D (WinRho SD) treatment of children with chronic autoimmune thrombocytopenic purpura stimulates transient cytokine/chemokine production.

    PubMed

    Semple, J W; Allen, D; Rutherford, M; Woloski, M; David, M; Wakefield, C; Butchart, S; Freedman, J; Blanchette, V

    2002-03-01

    Intravenous anti-D is often used in the treatment of autoimmune thrombocytopenic purpura (AITP), but little is known about its mechanisms of action. To investigate anti-D's potential in vivo mechanism(s) of action, a small group (N = 7) of children with chronic AITP was studied. The children initially received either 25 or 50 microg/kg of WinRho-SD in a four-cycle cross-over trial, and peripheral blood samples from the first and third cycles were assessed for cytokine levels at pre-treatment, 3 hr, 1 day, and 8 days post-treatment. Results showed that platelet counts significantly increased in all the children by day 8 post-treatment. Analysis of serum by ELISA showed that there was a significant but transient rise in both pro- and anti-inflammatory cytokine/chemokine levels (e.g., IL1RA, IL6, GM-CSF, MCP-1 alpha, TNF-alpha and MCP-1) by 3 hr post-treatment in both cycles which returned to baseline levels by 8 days post-treatment. These results suggest that anti-D administration may initially activate the RES in the form of cytokine/chemokine secretion, which is subsequently followed by an increase in platelet counts. It is possible that the induced cytokine/chemokine storm may have an effect on several physiological processes such as those mediating either adverse effects or potentially RES phagocytic activity. PMID:11891813

  10. Synergistic Effects of [Ile⁷]Surfactin Homologues with Bacillomycin D in Suppression of Gray Mold Disease by Bacillus amyloliquefaciens Biocontrol Strain SD-32.

    PubMed

    Tanaka, Keijitsu; Amaki, Yusuke; Ishihara, Atsushi; Nakajima, Hiromitsu

    2015-06-10

    We previously reported that Bacillus amyloliquefaciens biocontrol strain SD-32 produces powerful antifungal lipopeptides, C17 bacillomycin D homologues. In the course of the investigation we found that the antifungal activity of the culture supernatant of this bacterium was not ascribed exclusively to bacillomycin D. We attempted to identify metabolites other than bacillomycin D to gain insight into the mechanism for the biocontrol by this bacterium. After purifying the fractions of the culture supernatant exhibiting synergistic activity with bacillomycin D, we isolated two new cyclic lipodepsipeptides, anteiso-C13 and iso-C13 [Ile(7)]surfactins, together with three known [Ile(7)]surfactins. Interestingly, [Ile(7)]surfactins showed synergistic activities with bacillomycin D to gray mold disease on cucumber leaves but not to Botrytis cinerea itself in vitro, suggesting that the synergistic effects might be on infection processes of the fungus. Actually, we observed that they did not show synergistic actions on conidial germination or mycelial growth of B. cinerea on the leaves. PMID:25976169

  11. Analysis of aquifer tests conducted in boreholes USW WT-10, UE-25 WT No. 12, and USW SD-7, 1995-96, Yucca Mountain, Nevada

    SciTech Connect

    O`Brien, G.M.

    1997-09-01

    Single-borehole aquifer tests were conducted in three boreholes in the Yucca Mountain area between March 1995 and January 1996 to obtain estimates of borehole specific capacity and aquifer transmissivity. Analysis of aquifer testing in borehole USW SD-7 also resulted in an estimate of reservoir volume. Aquifer-test data were analyzed with the Cooper and Jacob straight-line method, two modified Theis nonequilibrium equation solutions, and a modified reservoir-limit solution. The highest estimates of transmissivity were in borehole USW WT-10, completed in the Topopah Spring Tuff. Mean transmissivity, based on the results of three drawdown tests, was 1,600 meters squared per day. Mean specific capacity in borehole USW WT-10 after 5 hours of pumping was 1,100 meters squared per day, and was estimated to be 740 meters squared per day after 24 hours of pumping. Aquifer testing in borehole UE-25 WT No. 12 appeared to be significantly affected by well losses. A mean transmissivity of 7 meters squared per day was obtained on the basis of analysis of three drawdown tests in borehole UE-25 WT No. 12. Mean specific capacity in borehole UE-25 WT No. 12, after 24 hours of pumping, was 7 meters squared per day. Borehole UE-25 WT No. 12 seemed to be producing water from fractures that could provide only a limited amount of water to the borehole.

  12. Doping effects of Co and Cu on superconductivity and magnetism in Fe1+yTe0.6Se0.4 single crystals.

    PubMed

    Zhang, Z T; Yang, Z R; Li, L; Ling, L S; Zhang, C J; Pi, L; Zhang, Y H

    2013-01-23

    We report on the investigation of Co and Cu substitution effects on superconductivity and magnetism in Fe(1+y)Te(0.6)Se(0.4) single crystals. The parent Fe(1.01)Te(0.59)Se(0.41) shows a nodeless bulk superconductivity as revealed in heat capacity measurement, which is gradually suppressed by either Co or Cu doping. It is found that the Co or Cu doping mainly serves as scatterers rather than charge carrier doping, which is in agreement with the DFT calculation (2010 Phys. Rev. Lett. 105 157004) reported by Wadati et al. In comparison with Cu doping, Co doping shows a stronger influence on magnetism while a less evident suppression effect on superconductivity. Upon substitution of Co for Fe, a Schottky heat capacity anomaly develops gradually at low temperatures, implying the existence of a paramagnetic moment in the Co-doped samples. In contrast, Cu doping may mainly serve as non-magnetic scatterers, where no Schottky anomaly is observed. PMID:23238220

  13. Electrical behavior of nano-polycrystalline (La 1- yK y) 0.7Ba 0.3MnO 3 manganites

    NASA Astrophysics Data System (ADS)

    Mazaheri, M.; Akhavan, M.

    2010-11-01

    We present a study of the structural and electrical behavior of nano-polycrystalline mixed barium and alkali substituted lanthanum-based manganite, (La 1- yK y) 0.7Ba 0.3MnO 3 with y=0.0-0.3. The samples were synthesized by the polymerization complex sol-gel method. The powder X-ray diffraction (XRD) data of the samples show a single-phase character with R3¯c space group. The magnetic and electrical transport properties of the nano-polycrystalline samples have been investigated in the temperature range 50-300 K and a magnetic field up to 10 kOe. The metal-insulator transition temperature Tp of all the samples decreased with potassium doping, and also, it increased slightly with the application of magnetic field. The low field magnetoresistance, which is absent in the single-crystalline perovskite, was observed and increased with decreasing temperature. Comparing the experimental resistivity data with the theoretical models shows that the high temperature electrical behavior of these samples is in accordance with the adiabatic small polaron-hopping model. In the metal-ferromagnetic region the resistivity is found to be quite well described by ρ=ρ0+ρ2T2+ρ4.5T4.5.

  14. Determination of the easy axis of magnetization in terbium-yttrium iron garnet Tb1Y2Fe5O12 at low temperatures

    NASA Astrophysics Data System (ADS)

    Lahoubi, Mahieddine; Wang, Wei; Pu, Shengli

    2015-11-01

    Experimental investigations have been carried out on a spherical single crystal of terbium yttrium iron garnet (Tb1Y2Fe5O12) by means of magnetization measurements in strong dc magnetic fields up to 200 kOe applied along the <111>, <110> and <100> crystallographic directions at low temperatures (T<20 K) with a high degree of resolution both in field and temperature. The strong anisotropic magnetic behavior which appears at 4.2 K is due to the competition between <111> and <100> directions to be the easy axis of spontaneous magnetization while the <110> direction remains the more difficult axis. The magnetization measurement at 4.2 K leaving the sample to rotate freely on itself suggests that the easy axis of spontaneous magnetization is along the <100> direction. However, due to the magnetic anisotropy energies associated with both <100> and <111> directions which are close to each other, the phase <111> becomes more stable as soon as the magnetic field exceeds 10 kOe or the temperature is higher than 10 K. The results are compared with previous works.

  15. Raman spectroscopy characterization of actinide oxides (U 1-yPu y)O 2: Resistance to oxidation by the laser beam and examination of defects

    NASA Astrophysics Data System (ADS)

    Jégou, C.; Caraballo, R.; Peuget, S.; Roudil, D.; Desgranges, L.; Magnin, M.

    2010-10-01

    Structural changes in four (U 1-yPu y)O 2 materials with very different plutonium concentrations (0 ⩽ y ⩽ 1) and damage levels (up to 110 dpa) were studied by Raman spectroscopy. The novel experimental approach developed for this purpose consisted in using a laser beam as a heat source to assess the reactivity and structural changes of these materials according to the power supplied locally by the laser. The experiments were carried out in air and in water with or without hydrogen peroxide. As expected, the material response to oxidation in air depends on the plutonium content of the test oxide. At the highest power levels U 3O 8 generally forms with UO 2 whereas no significant change in the spectra indicating oxidation is observed for samples with high plutonium content ( 239PuO 2). Samples containing 25 wt.% plutonium exhibit intermediate behavior, typified mainly by a higher-intensity 632 cm -1 peak and the disappearance of the 1LO peak at 575 cm -1. This can be attributed to the presence of anion sublattice defects without any formation of higher oxides. The range of materials examined also allowed us to distinguish partly the chemical effects of alpha self-irradiation. The results obtained with water and hydrogen peroxide (a water radiolysis product) on a severely damaged 238PuO 2 specimen highlight a specific behavior, observed for the first time.

  16. Effect of Surface Preparation on Mechanical Properties of Ni Contacts on Polycrystalline (Bi1- x Sb x )2(Te1- y Se y )3 Alloys

    NASA Astrophysics Data System (ADS)

    Kashi, S.; Keshavarz, M. K.; Vasilevskiy, D.; Masut, R. A.; Turenne, S.

    2012-06-01

    We present a comparison of different surface preparation techniques for hot-extruded (Bi1- x Sb x )2(Te1- y Se y )3 alloys prior to Ni plating and their consequences on adhesion. The surface preparation is carried out by a relatively fast and well-controlled electrochemical etching procedure that provides morphologies with homogeneous flat surfaces on a scale of tens of micrometers. This procedure is not optimal for Ni metallization since it does not ensure enough roughness on the surface. Applying wet chemical etching with hypochlorite and nitric acid after the electrochemical etching changes the morphology, and the surface roughness increases, as evidenced by scanning electron microscopy and atomic force microscopy. Tensile tests carried out on n-type and p-type 1-mm-thick specimens, covered with a 12- μm Ni layer followed by Sn-Pb soldered joints, confirm a significant improvement in the ultimate adhesion strength, with fracture occurring within the thermoelectric material. Use of this two-step surface treatment, after slicing and prior to metallization, leads to maximum adhesion strength of around 38 MPa for either type of thermoelectric material. These results are consistent with the morphological changes observed by scanning electron microscopy on the surface after chemical etching.

  17. Growth and characterization of highly tensile strained Ge1-xSnx formed on relaxed InyGa1-yP buffer layers

    NASA Astrophysics Data System (ADS)

    Wang, Wei; Loke, Wan Khai; Yin, Tingting; Zhang, Zheng; D'Costa, Vijay Richard; Dong, Yuan; Liang, Gengchiau; Pan, Jisheng; Shen, Zexiang; Yoon, Soon Fatt; Tok, Eng Soon; Yeo, Yee-Chia

    2016-03-01

    Ge0.94Sn0.06 films with high tensile strain were grown on strain-relaxed InyGa1-yP virtual substrates using solid-source molecular beam epitaxy. The in-plane tensile strain in the Ge0.94Sn0.06 film was varied by changing the In mole fraction in InxGa1-xP buffer layer. The tensile strained Ge0.94Sn0.06 films were investigated by transmission electron microscopy, x-ray diffraction, and Raman spectroscopy. An in-plane tensile strain of up to 1% in the Ge0.94Sn0.06 was measured, which is much higher than that achieved using other buffer systems. Controlled thermal anneal experiment demonstrated that the strain was not relaxed for temperatures up to 500 °C. The band alignment of the tensile strained Ge0.94Sn0.06 on In0.77Ga0.23P was obtained by high resolution x-ray photoelectron spectroscopy. The Ge0.94Sn0.06/In0.77Ga0.23P interface was found to be of the type I band alignment, with a valence band offset of 0.31 ± 0.12 eV and a conduction band offset of 0.74 ± 0.12 eV.

  18. Dynamics and mechanism of oxygen annealing in Fe1+yTe0.6Se0.4 single crystal.

    PubMed

    Sun, Yue; Tsuchiya, Yuji; Taen, Toshihiro; Yamada, Tatsuhiro; Pyon, Sunseng; Sugimoto, Akira; Ekino, Toshikazu; Shi, Zhixiang; Tamegai, Tsuyoshi

    2014-01-01

    Iron chalcogenide Fe(Te,Se) attracted much attention due to its simple structure, which is favorable for probing the superconducting mechanism. Its less toxic nature compared with iron arsenides is also advantageous for applications of iron-based superconductors. By intercalating spacer layers, superconducting transition temperature has been raised over 40 K. On the other hand, the presence of excess Fe is almost unavoidable in Fe(Te,Se) single crystals, which hinders the appearance of bulk superconductivity and causes strong controversies over its fundamental properties. Here we report a Systematical study of O2-annealing dynamics in Fe(1+y)Te(1-x)Sex by controlling the amount of O2, annealing temperature, and time. Bulk superconductivity can be gradually induced by increasing the amount of O2 and annealing time at suitable temperatures. The optimally annealed crystals can be easily obtained by annealing with ~1.5% molar ratio of oxygen at 400 °C for more than 1 hour. Superconductivity was witnessed to evolve mainly from the edge of the crystal to the central part. After the optimal annealing, the complete removal of excess Fe was demonstrated via STM measurements. Some fundamental properties were recharacterized and compared with those of as-grown crystals to discuss the influence of excess Fe. PMID:24695095

  19. In-plane/out-of-plane disorder influence on the magnetic anisotropy of Fe1-yMnyPt-L10 bulk alloy

    NASA Astrophysics Data System (ADS)

    Cuadrado, R.; Liu, Kai; Klemmer, Timothy J.; Chantrell, R. W.

    2016-03-01

    The random substitution of a non-magnetic species instead of Fe atoms in FePt-L10 bulk alloy will permit to tune the magnetic anisotropy energy of this material. We have performed by means of first principles calculations a study of Fe1-yMnyPt-L10 (y = 0.0, 0.08, 0.12, 0.17, 0.22, and 0.25) bulk alloy for a fixed Pt concentration when the Mn species have ferro-/antiferromagnetic (FM,AFM) alignment at the same(different) atomic plane(s). This substitution will promote several in-plane lattice values for a fixed amount of Mn. Charge hybridization will change compared to the FePt-L10 bulk due to this lattice variation leading to a site resolved magnetic moment modification. We demonstrate that this translates into a total magnetic anisotropy reduction for the AFM phase and an enhancement for the FM alignment. Several geometric configurations were taken into account for a fixed Mn concentration because of different possible Mn positions in the simulation cell.

  20. Optimization of growth conditions for (La1-yPry)1-x CaxMnO3 thin films on annealed oxide substrates

    NASA Astrophysics Data System (ADS)

    Schaefer, Brian; Grant, Daniel; Biswas, Amlan

    2014-03-01

    Consistent growth of flat, epitaxial thin films is essential for uncovering the unique transport characteristics of rare-earth manganite systems. We have developed pulsed laser deposition growth conditions for (La1-yPry)1-x CaxMnO3 (LPCMO, y = 0.4, 0.5, 0.6) thin films on annealed NdGaO3 (NGO) and SrTiO3 (STO) substrates. The extra annealing step for NGO and STO produces atomically flat substrates with well-defined terraces of unit cell step height. Films grown on these annealed substrates demonstrate better lattice matching compared to films grown on as-received substrates. Consequently, annealing substrates before film growth leads to higher quality thin films with a more controllable thickness. We demonstrate that these optimized growth parameters yield LPCMO thin films that are also atomically flat, as confirmed by atomic force microscopy. We are using these thin films to restrict phase growth to reduced dimensions and to study the origin of thermodynamic phase competition due to first order transitions in manganites. NSF DMR-0804452

  1. Quaternary phase diagrams of spinel Liy□1-yMnxNi2 -xO4 and composite cathode voltages for concentration gradient materials

    NASA Astrophysics Data System (ADS)

    Hao, Shiqiang; Lu, Zhi; Wolverton, Christopher

    2016-07-01

    Core-shell coating structures and concentration gradient materials may enhance Li-ion battery performance by integrating advantages of core and shell components without introducing unfavorable problems associated with general coatings. The fundamental thermodynamic properties of concentration gradient composite materials are complex due to the multicomponent nature of the problem. We systematically study the thermodynamics of ordering and phase separation in the quaternary spinel Liy□1-yMnxNi2 -xO4 (□ means vacancy) system by density functional theory calculations, together with the coupled cluster expansion method with interactions within and between (Li/□) and (Mn/Ni) sublattices. On the basis of coupled cluster expansion interactions and Monte Carlo simulations, we calculate quaternary phase diagrams as a function of temperature as well as voltage profiles of single ordered phases and multiphase composite structures. The phase diagram and voltage results are in good agreement with available experimental observations. We also predict a stable high-voltage ordered compound LiMnNiO4, with a very high delithiation voltage of 4.76 V. For the composite (Mn-rich+Ni -rich) cathode materials, the voltage profiles show combinations of plateaus from each component compound. The computational strategy of combining quaternary phase diagrams with voltage calculations provides a pathway to understand and design concentration gradient materials.

  2. Effect of Transition Metal Ordering on the Electronic Properties of LiNi1 - y - xCoyMnxO2 Cathode Materials for Li-ion Batteries

    NASA Astrophysics Data System (ADS)

    Longo, Roberto; Kong, Fantai; Kc, Santosh; Yeon, Dong-Hee; Yoon, Jaegu; Park, Jin-Hwan; Doo, Seok-Kwang; Cho, Kyeongjae; MSL Team; SAIT Team

    2015-03-01

    Current Li-ion batteries use layered oxides as cathode materials, specially LiCoO2 or LiNi1 - y - xCoyMnxO2(NCM), and graphite as anode. Co layered oxides suffer from the high cost and toxicity of cobalt, together with certain instability at high operational temperatures. To overcome these difficulties, the synthesis of novel materials composed of layered oxides with different sets of Transition Metals (TM) has become the most successful way to solve the particular drawbacks of every single-oxide family. Although layered materials can deliver larger capacity than other families of cathode materials, the energy density has yet to be increased in order to match the expectations deposited on the NCM oxides. To acquire a high capacity, they need to be cycled at high operational voltages, resulting in voltage and capacity fading over a large number of cycles. In this work, we examine the phase diagram of the Li-Ni-Co-Mn-O system and the effect of TM ordering on the electronic properties of NCM cathode materials, using density-functional theory. Our findings will provide conceptual guidance in the experimental search for the mechanisms driving the voltage and capacity fading of the NCM family of cathode materials, in an attempt to solve such structural instability problems and, thus, improving the performance of the NCM cathode materials. This work was supported by Samsung GRO project.

  3. Hydrogen motion and local structure of metals in β-Ti1-yVyHx as studied by 1H NMR

    NASA Astrophysics Data System (ADS)

    Ueda, Takahiro; Hayashi, Shigenobu; Hayamizu, Kikuko

    1993-09-01

    Hydrogen motion in β-Ti1-yVyHx (y=0.2, 0.4, 0.6, and 0.8; x~1) alloys was studied by 1H NMR, with which the temperature and frequency dependences of proton spin-lattice relaxation times (T1) were measured over the temperature range 105-400 K and at frequencies 9, 22.5, 52, and 90 MHz. The temperature dependences of T1 change systematically with the metal composition; with a decrease in the concentration of V, the minimum value of T1 increases and the temperature at which T1 is minimized shifts to the higher-temperature side. These results are analyzed with two-site jumps of a proton between unequal potential wells, in which Brouwer's model is assumed to describe local structure of the alloys. Good agreement between the experimental and calculated T1 values is given by this treatment, unlike the isotropic diffusion model. The following three parameters are used for the calculation: activation energies for Ti and V are ETi=16 and EV=9.5 kJ/mol, respectively, and the frequency prefactor is τ0=1.5×10-11 s for 0.4<=y<=0.8. The obtained ETi and EV values agree with those of pure metal hydrides such as TiHx and VHx, respectively.

  4. High-Tc Nodeless s±-wave Superconductivity in (Y,La)FeAsO1-y with Tc=50K:As75-NMR Study

    NASA Astrophysics Data System (ADS)

    Mukuda, H.; Furukawa, S.; Kinouchi, H.; Yashima, M.; Kitaoka, Y.; Shirage, P. M.; Eisaki, H.; Iyo, A.

    2012-10-01

    We report on an As75-NMR study on the Fe-pnictide high-Tc superconductor Y0.95La0.05FeAsO1-y (Y0.95La0.051111) with Tc=50K that includes no magnetic rare-earth elements. The measurement of the nuclear-spin lattice-relaxation rate (751/T1) has revealed that the nodeless bulk superconductivity takes place at Tc=50K while antiferromagnetic spin fluctuations develop moderately in the normal state. These features are consistently described by the multiple fully gapped s±-wave model based on the Fermi-surface nesting. Incorporating the theory based on band calculations, we propose that the reason that Tc=50K in Y0.95La0.051111 is larger than Tc=28K in La1111 is that the Fermi-surface multiplicity is maximized, and hence the Fermi-surface nesting condition is better than that in La1111.

  5. Giant superconducting fluctuation and anomalous semiconducting normal state in NdO1-xFxBi1-yS2 single crystals

    NASA Astrophysics Data System (ADS)

    Liu, Jianzhong; Fang, Delong; Wang, Zhenyu; Xing, Jie; Du, Zengyi; Li, Sheng; Zhu, Xiyu; Yang, Huan; Wen, Hai-Hu

    2014-06-01

    We report the successful growth of the \\text{NdO}_{1-x}\\text{F}_x\\text{Bi}_{1-y}\\text{S}_2 single crystals and prove the intrinsic superconductivity. Resistive and magnetic measurements reveal that the bulk superconducting transition occurs at T_c = 4.83\\ \\text{K} . Measurements of excess conductivity and the in-plane angle-dependent resistance reveal a giant superconducting fluctuation far above Tc (extending to 2T_c\\text{-}4T_c ). This is supported by the Nernst and the scanning tunneling measurements. Analysis based on the anisotropic Ginzburg-Landau theory gives a very large anisotropy \\gamma=\\sqrt{m_c/m_{ab}}\\approx30\\text{-}50 . Two gap features with magnitudes of about 3.5 +/- 0.3\\ \\text{meV} and 7.5 +/- 1\\ \\text{meV} were observed by scanning tunneling spectroscopy. The smaller gap is associated with the bulk superconducting transition yielding a huge ratio 2\\Delta^{1}_s/k_BT_c=16.8 , and the gapped feature remains up to 20-30 K. Another fascinating phenomenon is that the normal state recovered by applying a high magnetic field along the c-axis shows an anomalous semiconducting behavior. All these suggest that the superconductivity in this newly discovered superconductor may have an exotic reason which is beyond the BCS picture.

  6. Modeling preparation condition and composition-activity relationship of perovskite-type LaxSr1-xFeyCo1-yO3 nano catalyst.

    PubMed

    Oskoui, Samira Arefi; Niaei, Aligholi; Tseng, Hui-Hsin; Salari, Dariush; Izadkhah, Behrang; Hosseini, Seyed Ali

    2013-12-01

    In this paper, an artificial neural network (ANN) is first applied to perovskite catalyst design. A series of perovskite-type oxides with the LaxSr1-xFeyCo1-yO3 general formula were prepared with a sol-gel autocombustion method under different preparation conditions. A three-layer perceptron neural network was used for modeling and optimization of the catalytic combustion of toluene. A high R2 value was obtained for training and test sets of data: 0.99 and 0.976, respectively. Due to the presence of full active catalysts, there was no necessity to use an optimizer algorithm. The optimum catalysts were La0.9Sr0.1Fe0.5Co0.5O3 (Tc=700 and 800 °C and [citric acid/nitrate]=0.750), La0.9Sr0.1Fe0.82Co0.18O3 (Tc=700 °C, [citric acid/nitrate]=0.750), and La0.8Sr0.2Fe0.66Co0.34O3 (Tc=650 °C, [citric acid/nitrate]=0.525) exhibiting 100% conversion for toluene. More evaluation of the obtained model revealed the relative importance and criticality of preparation parameters of optimum catalysts. The structure, morphology, reducibility, and specific surface area of catalysts were investigated with XRD, SEM, TPR, and BET, respectively. PMID:24102474

  7. Model of infiltrated La1-xSrxCo1-yFeyO3-δ cathodes for intermediate temperature solid oxide fuel cells

    NASA Astrophysics Data System (ADS)

    Enrico, Anna; Costamagna, Paola

    2014-12-01

    We consider an LSCF (La1-xSrxCo1-yFeyO3-δ) cathode formed of straight fibers. Being LSCF a mixed ionic electronic conductor (MIEC), we consider that it features two separate charge conduction paths, one for electrons and one for oxygen-ions. Infiltrated dopant particles, adherent to the LSCF fibers, create contact points between the ionic and the electronic conductive paths, among which, otherwise, the charge transfer reaction would be negligible. Based on this picture of the doped LSCF electrode, a model is developed. The model includes the evaluation of (i) electron and oxygen-ion conduction along the LSCF fiber, and (ii) charge transfer reaction occurring at the doping particles and, possibly, at the electrode/electrolyte interface. The model is applied to infiltrated cathodes based on different LSCF scaffolds, and the results are compared to literature experimental data, demonstrating good agreement. In particular, the model captures well the improvement of performance of the doped electrodes over the undoped ones, which can be five to tenfold or even more, and can bring the 1/Rp values to the order of magnitude of 105 S m-2 at 1000 K. Deviations between model results and literature experimental data at high doping levels are discussed in terms of percolation and partial pore obstruction.

  8. Observation of acoustic-phonon-like mode driven by magnetic imbalance between neighboring Fe atoms in Fe1+yTe (y < 0 . 12)

    NASA Astrophysics Data System (ADS)

    Fobes, David; Zaliznyak, Igor; Xu, Zhijun; Gu, Genda; Tranquada, John M.; He, Xu-Gang; Ku, Wei; Garlea, Ovidiu

    2014-03-01

    We have studied the evolution with temperature of the low-energy inelastic spectra of Fe1+yTe (y < 0 . 12), a parent compound of the iron-chalcogenide superconductor family, revealing an acoustic mode at an unexpected position. Recently, we found evidence for the formation of a bond-order wave leading to ferro-orbital order in the monoclinic phase, in part due to the observation of an elastic structural peak at (100) in the low-temperature monoclinic phase [D. Fobes, et al., arXiv:1307.7162]. In the inelastic spectra we observe a sharp acoustic-phonon-like mode dispersing out of the (100) position in the monoclinic phase. Surprisingly, the mode survives in the tetragonal phase, despite the absence of a Bragg peak at (100); such a peak is forbidden by symmetry. LDA calculations suggest this mode could involve significant magnetic scattering. By assuming in-phase virtual displacement of the Fe atoms from their equilibrium position in a frozen phonon calculation, we have found a small but significant imbalance in the magnetic moments between the two Fe atoms within the unit cell, suggesting magnetic contribution to the mode. Work at BNL supported by Office of Basic Energy Sciences, US DOE, under Contract No. DE-AC02-98CH10886. Research conducted at ORNL Spallation Neutron Source was sponsored by the Scientific User Facilities Division, Office of Basic Energy Sciences, US DOE.

  9. Chromosome landmarks and autosome-sex chromosome translocations in Rumex hastatulus, a plant with XX/XY1Y2 sex chromosome system.

    PubMed

    Grabowska-Joachimiak, Aleksandra; Kula, Adam; Książczyk, Tomasz; Chojnicka, Joanna; Sliwinska, Elwira; Joachimiak, Andrzej J

    2015-06-01

    Rumex hastatulus is the North American endemic dioecious plant with heteromorphic sex chromosomes. It is differentiated into two chromosomal races: Texas (T) race characterised by a simple XX/XY sex chromosome system and North Carolina (NC) race with a polymorphic XX/XY1Y2 sex chromosome system. The gross karyotype morphology in NC race resembles the derived type, but chromosomal changes that occurred during its evolution are poorly understood. Our C-banding/DAPI and fluorescence in situ hybridization (FISH) experiments demonstrated that Y chromosomes of both races are enriched in DAPI-positive sequences and that the emergence of polymorphic sex chromosome system was accompanied by the break of ancestral Y chromosome and switch in the localization of 5S rDNA, from autosomes to sex chromosomes (X and Y2). Two contrasting domains were detected within North Carolina Y chromosomes: the older, highly heterochromatinised, inherited from the original Y chromosome and the younger, euchromatic, representing translocated autosomal material. The flow-cytometric DNA estimation showed ∼3.5 % genome downsizing in the North Carolina race. Our results are in contradiction to earlier reports on the lack of heterochromatin within Y chromosomes of this species and enable unambiguous identification of autosomes involved in the autosome-heterosome translocation, providing useful chromosome landmarks for further studies on the karyotype and sex chromosome differentiation in this species. PMID:25394583

  10. Effect of Mg doping on the local structure of LiMgyCo1-yO2 cathode material investigated by X-ray absorption spectroscopy

    NASA Astrophysics Data System (ADS)

    Cheng, J. H.; Pan, C. J.; Nithya, C.; Thirunakaran, R.; Gopukumar, S.; Chen, C. H.; Lee, J. F.; Chen, J. M.; Sivashanmugam, A.; Hwang, B. J.

    2014-04-01

    A higher capacity and better cyclability are apparent when magnesium is introduced into the structure of LiCoO2 (y = 0.15). XRD analysis of LiMgyCo1-yO2 (y = 0, 0.1, 0.15), synthesized at 800 °C using a microwave assisted method, shows that the material is in the R-3m space group and to have a slightly expanded unit cell that increases with greater magnesium doping. Structural analysis by X-ray absorption spectroscopy (XAS) at the Co K-edge, L-edge and O K-edge shows that the magnesium is located in the transition metal layer rather than in the lithium layer and the charge balance results from the formation of oxygen vacancies rather than Co4+, while cobalt remains in the 3+ oxidation state. Interestingly, oxygen is found to participate in the charge compensation. Both magnesium, in the transition metal layer, and the Co-defect structure are attributed to the contribution towards structural stabilization of LiCoO2, thereby resulting in its enhanced electrochemical performance.

  11. Effects of counter-doping on the transport and magnetic properties of Ga_1-xMn_xAs_1-yTe _y

    NASA Astrophysics Data System (ADS)

    Scarpulla, M. A.; Dubon, O. D.; Yu, K. M.; Walukiewicz, W.

    2004-03-01

    It has been demonstrated that the Fermi level-induced reduction of the formation energy of interstitial Mn donors limits the maximum concentrations of magnetically active substitutional Mn_Ga acceptors and free holes in Ga_1-xMn_xAs [K.M. Yu, et al., Phys. Rev. B 65, 201303 (2002)]. This saturation level limits the Curie temperature (T_C) of films thicker than 60 nm to ˜110 K. It has been suggested that it may be possible increase TC by intentionally doping Ga_1-xMn_xAs with donors. Such counter-doping would stabilize the Fermi energy and prevent the transfer of Mn atoms from substitutional to interstitial sites [K.M. Yu, et al., Phys. Rev. B 68, 041308 (2003)]. To test this hypothesis we have used ion-implantation and pulsed laser melting to introduce Te donors. This counter doping scheme decouples the concentrations of local spins and holes, allowing us to probe the interaction of carrier transport and ferromagnetism. We have observed that strong ferromagnetism in Ga_1-xMn_xAs_1-yTey coexists with hopping conduction at low temperatures, which is in contrast to the metallic behavior usually observed in Ga_1-xMn_xAs films with x>0.03. This work was supported in part by the U.S. DOE under Contract No. DE-AC03-76SF00098 and by the Hellman Fund.

  12. Lasing characteristics of Yb-doped gadolinium yttrium mixed oxyorthosilicate Yb:(Gd0.1Y0.9)2SiO5

    NASA Astrophysics Data System (ADS)

    Chu, Hongwei; Zhao, Shengzhi; Yang, Kejian; Zhao, Jia; Li, Dechun; Li, Guiqiu; Li, Tao; Qiao, Wenchao; Xu, Xiaodong; Zheng, Lihe; Xu, Jun

    2015-07-01

    A continuous wave (CW) tunable laser based on an alloyed oxyorthosilicate Yb:(Gd0.1Y0.9)2SiO5 was demonstrated for the first time. With an output coupler (OC) of T = 10%, a maximum output power of 958 mW was obtained with a slope efficiency of 18.2%. Simultaneous multi-wavelength operation was also observed with an OC of T = 4%. The M2 factor of the CW laser beam was measured to be 1.06. The thermo-optic coefficient was estimated to be 7.1 × 10-6/K. By using a 400 μm-thick GaAs wafer as saturable absorber, a stably Q-switched laser at 1080.4 nm was also firstly realized. A minimum pulse duration of 60.2 ns was obtained with a repetition rate of 47.6 kHz under an absorbed pump power of 11.25 W. The corresponding highest pulse energy and peak power were 5.3 μJ and 88 W, respectively. By using a V-type cavity and an OC of T = 4%, the laser can be tuned in the range from 1021 to 1094 nm.

  13. Laxative effects of Liriope platyphylla are tightly correlated with suppression of endoplasmic reticulum stress in loperamide-induced constipation of SD rats

    PubMed Central

    Kim, Ji-Eun; Go, Jun; Sung, Ji-Eun; Lee, Hyun-Ah; Seo, Eun-Ji; Yun, Woo-Bin

    2016-01-01

    A dysfunction of endoplasmic reticulum (ER) stress response can result in various diseases, including cancer, inflammation, diabetes and neurodegenerative disorders. To investigate whether ER stress response can play an essential role in the induction and treatment of chronic constipation, alterations in the key parameters for ER stress were measured in loperamide (Lop) induced constipation Sprague Dawley (SD) rats treated with aqueous extracts of Liriope platyphylla (AEtLP), which has been shown to have a laxative effect. Symptoms of chronic constipation including alteration of stool parameters and the transverse colon's structure were successfully induced by Lop treatment. Laxative effects such as enhancement of stools parameters, recovery of the mucosa thickness, increased muscle thickness and recovery of flat luminal surface were also observed in the Lop+AEtLP treated group. Furthermore, enhancement of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation and inositol-requiring enzyme 1 beta (IRE1β) expression, key indicators for ER stress, that were observed in the Lop+vehicle treated group were significantly recovered in the Lop+AEtLP treated group, although the phosphorylation level of c-Jun N-terminal protein kinase (JNK) remained constant. Moreover, alterations in the transcription level of the marker genes X-box binding protein 1 (XBP-1) and growth arrest and DNA damage-inducible protein (GADD34) were similar to those of eIF2α and IRE1β. However, their level was slightly or completely recovered after AEtLP treatment. Overall, this study provides the first evidence that ER stress response may be tightly correlated with chronic constipation induced by Lop treatment, as well as the laxative effects of AEtLP. PMID:27051439

  14. Characterization of Changes in Global Genes Expression in the Distal Colon of Loperamide-Induced Constipation SD Rats in Response to the Laxative Effects of Liriope platyphylla

    PubMed Central

    Kim, Ji Eun; Park, So Hae; Kwak, Moon Hwa; Go, Jun; Koh, Eun Kyoung; Song, Sung Hwa; Sung, Ji Eun; Lee, Hee Seob; Hong, Jin Tae; Hwang, Dae Youn

    2015-01-01

    To characterize the changes in global gene expression in the distal colon of constipated SD rats in response to the laxative effects of aqueous extracts of Liriope platyphylla (AEtLP), including isoflavone, saponin, oligosaccharide, succinic acid and hydroxyproline, the total RNA extracted from the distal colon of AEtLP-treated constipation rats was hybridized to oligonucleotide microarrays. The AEtLP treated rats showed an increase in the number of stools, mucosa thickness, flat luminal surface thickness, mucin secretion, and crypt number. Overall, compared to the controls, 581 genes were up-regulated and 216 genes were down-regulated by the constipation induced by loperamide in the constipated rats. After the AEtLP treatment, 67 genes were up-regulated and 421 genes were down-regulated. Among the transcripts up-regulated by constipation, 89 were significantly down-regulated and 22 were recovered to the normal levels by the AEtLP treatment. The major genes in the down-regulated categories included Slc9a5, klk10, Fgf15, and Alpi, whereas the major genes in the recovered categories were Cyp2b2, Ace, G6pc, and Setbp1. On the other hand, after the AEtLP treatment, ten of these genes down-regulated by constipation were up-regulated significantly and five were recovered to the normal levels. The major genes in the up-regulated categories included Serpina3n, Lcn2 and Slc5a8, whereas the major genes in the recovered categories were Tmem45a, Rerg and Rgc32. These results indicate that several gene functional groups and individual genes as constipation biomarkers respond to an AEtLP treatment in constipated model rats. PMID:26151867

  15. Gallotannin-Enriched Extract Isolated from Galla Rhois May Be a Functional Candidate with Laxative Effects for Treatment of Loperamide-Induced Constipation of SD Rats.

    PubMed

    Kim, Ji Eun; Go, Jun; Koh, Eun Kyoung; Song, Sung Hwa; Sung, Ji Eun; Lee, Hyun Ah; Lee, Young Hee; Hong, Jin Tae; Hwang, Dae Youn

    2016-01-01

    Several natural products containing tannins are used as traditional medicines for treatment of constipation; however, their pharmacological mechanism is not well understood. The laxative effects of gallotannin-enriched extract isolated from Galla Rhois (GEGR) were investigated using a constipation model induced by loperamide (Lop) injection. After analysis for antioxidant activity of GEGR, alterations in the excretion parameters, histological structure, mucin secretion, and related protein levels were measured in the transverse colon of Sprague Dawley (SD) rats with Lop-induced constipation following treatment with 250, 500 and 1,000 mg/ml of GEGR. The number and weight of feces increased significantly by 48-79% and 128-159%, respectively, in the Lop+GEGR treated group relative to the Lop+vehicle treated group, while food intake and water consumption were maintained at a constant level. The thickness of mucosa, muscle and flat luminal surface, as well as the number of goblet cells and crypt of lieberkuhn were enhanced in the Lop+GEGR treated group. Moreover, mucin secretion increased significantly in a dose dependent manner in the Lop+GEGR treated group. Furthermore, the downstream signaling pathway of the muscarinic acetylcholine receptors (mAChR) M2 and M3 was recovered by GEGR treatment, although the expression level varied. The levels of Gα expression and inositol triphosphate (IP3) concentration were also recovered in the Lop+GEGR treated group relative to the Lop+vehicle treated group. The results of the present study provide strong evidence that tannins distributed in various medicinal plants are important candidates for improving chronic constipation induced by Lop treatment in animal models. PMID:27618438

  16. Induction of Sd(a)-sialomucin and sulfated H-sulfomucin in mouse small intestinal mucosa by infection with parasitic helminth.

    PubMed

    Tsubokawa, Daigo; Ishiwata, Kenji; Goso, Yukinobu; Yokoyama, Takuya; Kanuka, Hirotaka; Ishihara, Kazuhiko; Nakamura, Takeshi; Tsuji, Naotoshi

    2015-06-01

    Mucin is a major component of mucus on gastrointestinal mucosa. Mucin alteration in the host is considered to be the principal event for expulsion of intestinal helminths. However, it is unclear what mucin alterations are induced by various helminth infections. In this study, the alterations of mouse small intestinal mucin after infection with two nematodes, Nippostrongylus brasiliensis and Heligmosomoides polygyrus, which parasitize the jejunal epithelium, and a cestode, Vampirolepis nana, which parasitizes the ileal epithelium, were examined biochemically and histologically using two anti-mucin monoclonal antibodies (mAbs), HCM31 and PGM34, which recognize Sd(a) antigen, NeuAcα2-3(GalNAcβ1-4)Galβ1-4GlcNAcβ-, and sulphated H type 2 antigen, Fucα1-2Galβ1-4GlcNAc(6SO₃H)β-, respectively. The goblet cell mucins that reacted with HCM31 increased conspicuously on the jejunal mucosa concurrently with expulsion of N. brasiliensis. Increased levels of HCM31-reactive mucins were observed in the jejunal mucosa after H. polygyrus infection, despite the ongoing parasitism. Goblet cell mucins that reacted with PGM34 increased on the ileal mucosa during V. nana parasitism. Small intestinal goblet cells reacting with the two mAbs were not observed in non-infected mice, although sialomucins and sulfomucins were abundantly present. Additionally, the number of ileal goblet cells that reacted with the two mAbs was increased at the time of expulsion of heterophyid trematode. These results indicate that the type of specific acidic mucins expressed after infection varies among species of intestinal helminth, and, furthermore, that the relationship with worm expulsion is also different. PMID:25819298

  17. Investigating the reversibility of structural modifications of LixNiyMnzCo1-y-zO₂ cathode materials during initial charge/discharge, at multiple length scales

    DOE PAGESBeta

    Hwang, Sooyeon; Bak, Seong -Min; Kim, Seung Min; Chung, Kyung Yoon; Chang, Wonyoung

    2015-08-11

    In this work, we investigate the structural modifications occurring at the bulk, subsurface, and surface scales of LixNiyMnzCo1-y-zO₂ (NMC; y, z = 0.8, 0.1 and 0.4, 0.3, respectively) cathode materials during the initial charge/discharge. Various analytical tools, such as X-ray diffraction, selected-area electron diffraction, electron energy-loss spectroscopy, and high-resolution electron microscopy, are used to examine the structural properties of the NMC cathode materials at the three different scales. Cut-off voltages of 4.3 and 4.8 V are applied during the electrochemical tests as the normal and extreme conditions, respectively. The high-Ni-content NMC cathode materials exhibit unusual behaviors, which is deviate frommore » the general redox reactions during the charge or discharge. The transition metal (TM) ions in the high-Ni-content NMC cathode materials, which are mostly Ni ions, are reduced at 4.8 V, even though TMs are usually oxidized to maintain charge neutrality upon the removal of Li. It was found that any changes in the crystallographic and electronic structures are mostly reversible down to the sub-surface scale, despite the unexpected reduction of Ni ions. However, after the discharge, traces of the phase transitions remain at the edges of the NMC cathode materials at the scale of a few nanometers (i.e., surface scale). This study demonstrates that the structural modifications in NMC cathode materials are induced by charge as well as discharge at multiple length scales. These changes are nearly reversible after the first cycle, except at the edges of the samples, which should be avoided because these highly localized changes can initiate battery degradation.« less

  18. AFM Morphology Study of Si1-Y GeY:H Films Deposited by LF PE CVD from Silane-Germane with Different

    SciTech Connect

    Sanchez, L; Kosarev, A

    2005-03-28

    The morphology of Si{sub 1-Y} Ge{sub Y}:H films in the range of Y=0.23 to 0.9 has been studied by AFM. The films were deposited by Low Frequency (LF) PE CVD at substrate temperature T{sub s}=300 C and discharge frequency f=110 kHz from silane+germane mixture with and without, Ar and H{sub 2} dilution. The films were deposited on silicon and glass substrates. AFM images were taken and analyzed for 2 x 2 mm{sup 2} area. All the images demonstrated ''grain'' like structure, which was characterized by the height distribution function F(H) average roughness , standard height deviation Rq, lateral correlation length L{sub c} area distribution function F(s), mean grain area , diameter distribution function F(d), and mean grain diameter . The roughness of the films monotonically increases with Y for all dilutions, but more significantly in the films deposited without dilution. L{sub c} continuously grows with Y in the films deposited without dilution, while more complex behavior L{sub c}(Y) is observed in the films deposited with H- or Ar dilution. The sharpness of F(H) characterized by curtosis {gamma} depends on dilution and the sharpest F(H) are for the films deposited with Ar ({gamma}=5.30,Y=0.23) and without dilution ({gamma}=4.3, Y=0.45). Isothermal annealing caused increase of , L{sub c} in the films deposited with H- and Ar dilutions, while in the films prepared without dilution the behavior was more complex, depending on the substrates. Significant narrowing of the height distribution was observed in the films deposited with H dilution or without dilution.

  19. Fully Coupled Modeling of Burnup-Dependent (U1- y , Pu y )O2- x Mixed Oxide Fast Reactor Fuel Performance

    NASA Astrophysics Data System (ADS)

    Liu, Rong; Zhou, Wenzhong; Zhou, Wei

    2016-03-01

    During the fast reactor nuclear fuel fission reaction, fission gases accumulate and form pores with the increase of fuel burnup, which decreases the fuel thermal conductivity, leading to overheating of the fuel element. The diffusion of plutonium and oxygen with high temperature gradient is also one of the important fuel performance concerns as it will affect the fuel material properties, power distribution, and overall performance of the fuel pin. In order to investigate these important issues, the (U1- y Pu y )O2- x fuel pellet is studied by fully coupling thermal transport, deformation, oxygen diffusion, fission gas release and swelling, and plutonium redistribution to evaluate the effects on each other with burnup-dependent models, accounting for the evolution of fuel porosity. The approach was developed using self-defined multiphysics models based on the framework of COMSOL Multiphysics to manage the nonlinearities associated with fast reactor mixed oxide fuel performance analysis. The modeling results showed a consistent fuel performance comparable with the previous results. Burnup degrades the fuel thermal conductivity, resulting in a significant fuel temperature increase. The fission gas release increased rapidly first and then steadily with the burnup increase. The fuel porosity increased dramatically at the beginning of the burnup and then kept constant as the fission gas released to the fuel free volume, causing the fuel temperature to increase. Another important finding is that the deviation from stoichiometry of oxygen affects greatly not only the fuel properties, for example, thermal conductivity, but also the fuel performance, for example, temperature distribution, porosity evolution, grain size growth, fission gas release, deformation, and plutonium redistribution. Special attention needs to be paid to the deviation from stoichiometry of oxygen in fuel fabrication. Plutonium content will also affect the fuel material properties and performance

  20. Low-temperature MOVPE using TEGa for suppressed layer undulation in InxGa1-xAs/GaAs1-yPy superlattice on vicinal substrates

    NASA Astrophysics Data System (ADS)

    Fujii, Hiromasa; Sodabanlu, Hassanet; Sugiyama, Masakazu; Nakano, Yoshiaki

    2015-03-01

    InxGa1-xAs/GaAs1-yPy strain-balanced superlattice (SL) is a promising narrow-gap material that can be lattice-matched to Ge or GaAs. When growing uniform SLs on vicinal substrates for Ge-based application, formation of step-bunching and the resultant layer undulation is a critical problem. The present paper reports low-temperature metal-organic vapor phase epitaxy (MOVPE) with triethylgallium (TEGa) to improve the stability and the uniformity of SL growth. Using trimetylgallium (TMGa), steps were severely bunched especially during InGaAs growth at high temperature, and the average reflectance of SLs significantly decreased due to lattice relaxation above 580 °C. Lowering the growth temperature to 550-530 °C was effective in order to grow 100-period SLs with a mirror-like surface, but an apparent lateral layer undulation was still confirmed by ex-situ X-ray-diffraction and STEM observation. Growth of SLs below 530 °C with TMGa was found to result in serious crystal degradation due to unstable growth in the kinetically-limited temperature range. In contrast, use of TEGa enabled 100-period SLs to be successfully grown even at lower temperature owing to its efficient pyrolysis process. Highly uniform SLs with negligible layer undulation were grown at 510 °C with TEGa, showing a photoluminescence spectrum which was as sharp as the one for SLs grown on an exact-oriented substrate. The absorption spectra for the SLs grown with TEGa showed similarly sharp edge with a strong exciton peak.

  1. Disorder-dependent superconducting phase diagram at high magnetic fields in Fe1+ySexTe1-x (x˜0.4)

    NASA Astrophysics Data System (ADS)

    Gebre, T.; Li, G.; Whalen, J. B.; Conner, B. S.; Zhou, H. D.; Grissonnanche, G.; Kostov, M. K.; Gurevich, A.; Siegrist, T.; Balicas, L.

    2011-11-01

    We compare the superconducting phase-diagram under high magnetic fields (up to H=45 T) of Fe1+ySe0.4Te0.6 single crystals originally grown by the Bridgman-Stockbarger (BRST) technique, which were annealed to display narrow superconducting transitions and the optimal transition temperature Tc≳14 K, with the diagram for samples of similar stoichiometry grown by the traveling-solvent floating-zone technique as well as with the phase diagram reported for crystals grown by a self-flux method. We find that the so-annealed samples tend to display higher ratios Hc2/Tc, particularly for fields applied along the interplanar direction, where the upper critical field Hc2(T) exhibits a pronounced concave down curvature followed by saturation at lower temperatures T. This last observation is consistent with previous studies indicating that this system is Pauli limited. An analysis of our Hc2(T) data using a multiband theory suggests the emergence of the Fulde-Ferrel-Larkin-Ovchnikov state at low temperatures. A detailed structural x-ray analysis, reveals no impurity phases but an appreciable degree of mosaicity in as-grown BRST single crystals that remains unaffected by the annealing process. Energy-dispersive x-ray analysis showed that the annealed samples have a more homogeneous stoichiometric distribution of both Fe and Se with virtually the same content of interstitial Fe as the nonannealed ones. Thus we conclude that the excess of Fe, in contrast to structural disorder, contributes to the decrease of the superconducting upper-critical fields of this series. Finally, a scaling analysis of the fluctuation conductivity in the superconducting critical regime, suggests that the superconducting fluctuations have a two-dimensional character in this system.

  2. Signs of high-temperature superconductivity in frustrated manganites La1 - y Sm y MnO3 + δ ( y = 0.85, 1)

    NASA Astrophysics Data System (ADS)

    Bukhanko, F. N.; Bukhanko, A. F.

    2016-03-01

    The characteristics signs of the coexistence of nanoscale superconductivity and fluctuating antiferromagnetic state of the spin-liquid type have been revealed for the first time in frustrated manganites La1‒ y Sm y MnO3 + δ (δ ~ 0.1, y = 0.85, 1.0) in the form of macroscopic quantization of magnetic properties in weak magnetic fields. A sharp decrease and oscillations of close-in-magnitude critical temperatures of transitions to fluctuating antiferromagnetic ( T A) and superconducting ( T c0) states with an increase in the external magnetic field strength have been found. Quantum oscillations of the magnetization and magnetic susceptibility near the critical temperatures of fluctuating antiferromagnetic phase transitions of the A- and CE-types have been discovered and investigated in detail. It has been shown that the studied samples exhibit properties of a multicomponent composite in which at temperatures T < 60 K in weak magnetic fields, there coexist fluctuating charge and antiferromagnetic correlations of the A- and CE-types with properties of the spin-liquid state and a small fraction of the superconducting phase in the form of individual and Josephsontunnel- junction-coupled superconducting loops with low critical currents. It has been assumed that, in samples with samarium concentrations y ≥ 0.8 at temperatures below 60 K, there is a new inhomogeneous state of doped manganites of the magneto-electronic liquid crystal type with strong quantum fluctuations of the magnetic and electronic order parameters, which are similar to electronic liquid crystals in lightly doped high-temperature superconducting cuprates.

  3. Interplay of superconductivity and d—f correlation in CeFeAs1-xPxO1-yFy

    NASA Astrophysics Data System (ADS)

    Luo, Yong-Kang; Li, Yu-Ke; Wang, Cao; Lin, Xiao; Dai, Jian-Hui; Cao, Guang-Han; Xu, Zhu-An

    2013-08-01

    The recent discovery of high-temperature superconductivity in iron-based pnictides (chalcogenides) not only triggers tremendous enthusiasm in searching for new superconducting materials, but also opens a new avenue to the study of the Kondo physics. CeFeAsO is a parent compound of the 1111-type iron-based superconductors. It shows 3d-antiferromagnetic (AFM) ordering below ~ 139 K and 4f-AFM ordering below ~ 4 K. On the other hand, the phosphide CeFePO is a ferromagnetically correlated heavy-fermion (HF) metal with Kondo scale TK ~ 10 K. These properties set up a new platform for research of the interplay among magnetism, Kondo effect, and superconductivity (SC). In this review, we present the recent progress in the study of chemical pressure effect in CeFeAsO1-yFy (y = 0 and 0.05). This P/As-doping in CeFeAsO serves as an effective controlling parameter which leads to two magnetic critical points, xc1 ≃ 0.4 and xc2 ≃ 0.92, associated with suppression of 3d and 4f magnetism, respectively. We also observe a turning point of AFM-FM ordering of Ce3+ moment at xc3 ≃ 0.37. The SC is absent in the phase diagram, which is attributed to the destruction to Cooper pair by Ce-FM fluctuations in the vicinity of xc1. We continue to investigate CeFeAs1-xPxO0.95F0.05. With the separation of xc1 and xc3, this chemical pressure results in a broad SC region 0<= x <= 0.53, while the original HF behavior is driven away by 5% F- doping. Different roles of P and F dopings are addressed, and the interplay between SC and Ce-4f magnetism is also discussed.

  4. Strain relaxation properties of InAs{sub y}P{sub 1-y} metamorphic materials grown on InP substrates

    SciTech Connect

    Hudait, Mantu K.; Lin, Y.; Ringel, S. A.

    2009-03-15

    The strain relaxation mechanism and defect properties of compositionally step-graded InAs{sub y}P{sub 1-y} buffers grown by molecular beam epitaxy on InP have been investigated. InAsP layers having lattice misfits ranging from 1% to 1.4% with respect to InP, as well as subsequently grown lattice matched In{sub 0.69}Ga{sub 0.31}As overlayers on the metamorphic buffers were explored on both (100) and 2 deg. offcut (100) InP substrates. The metamorphic graded buffers revealed very efficient relaxation coupled with low threading dislocation densities on the order of (1-2)x10{sup 6} cm{sup -2} for the range of misfit values explored here. A detailed analysis via high resolution x-ray diffraction revealed that the strain relaxed symmetrically, with equivalent numbers of {alpha} and {beta} dislocations, and to greater than 90% for all cases, regardless of substrate offcut. Further analysis showed the relaxation to always be glide limited in these materials when grown on a graded buffer compared to a single step layer. The threading dislocation density was observed by plan-view transmission electron microscopy to be constant for the range of misfit values studied here in the top layer of the graded structures, which is attributed to the very efficient use of residual dislocations and the dominance of dislocation glide over nucleation in these graded anion metamorphic buffers, suggesting great promise for metamorphic devices with lattice constants greater than that of InP to be enabled by InAsP metamorphic structures on InP.

  5. Report to the Legislature on Senate Concurrent Resolution 118 SD1 HD1: Improving the Community's Understanding of the Department of Education's Programs and School Expenses Including a Comparison with Other States on Adequacy of Funds

    ERIC Educational Resources Information Center

    Hawaii Educational Policy Center, 2008

    2008-01-01

    The 2007 Hawai'i State Legislature passed Senate Concurrent Resolution 118 S.D.1 HD 1 Improving the Community's Understanding of the Department of Education's Programs and School Expenses Including a Comparison with Other States on Adequacy of Funds. Among the requests contained in the resolution were the following: "Be it further resolved the…

  6. Transgenerational Effects of Di (2-Ethylhexyl) Phthalate in the Male CRL:CD(SD) Rat: Added Value of Assessing Multiple Offspring per Litter

    PubMed Central

    Gray, Leon Earl; Barlow, Norman J.; Howdeshell, Kembra L.; Ostby, Joseph S.; Furr, Johnathan R.; Gray, Clark L.

    2009-01-01

    In the rat, some phthalates alter sexual differentiation at relatively low dosage levels by altering fetal Leydig cell development and hormone synthesis, thereby inducing abnormalities of the testis, gubernacular ligaments, epididymis, and other androgen-dependent tissues. In order to define the dose-response relationship between di(2-ethylhexyl) phthalate (DEHP) and the Phthalate Syndrome of reproductive alterations in F1 male rats, Sprague-Dawley (SD) rat dams were dosed by gavage from gestational day 8 to day 17 of lactation with 0, 11, 33, 100, or 300 mg/kg/day DEHP (71–93 males per dose from 12 to 14 litters per dose). Some of the male offspring continued to be exposed to DEHP via gavage from 18 days of age to necropsy at 63–65 days of age (PUB cohort; 16–20/dose). Remaining males were not exposed after postnatal day 17 (in utero-lactational [IUL] cohort) and were necropsied after reaching full maturity. Anogenital distance, sperm counts and reproductive organ weights were reduced in F1 males in the 300 mg/kg/day group and they displayed retained nipples. In the IUL cohort, seminal vesicle weight also was reduced at 100 mg/kg/day. In contrast, serum testosterone and estradiol levels were unaffected in either the PUB or IUL cohorts at necropsy. A significant percentage of F1 males displayed one or more Phthalate Syndrome lesions at 11 mg/kg/day DEHP and above. We were able to detect effects in the lower dose groups only because we examined all the males in each litter rather than only one male per litter. Power calculations demonstrate how using multiple males versus one male/litter enhances the detection of the effects of DEHP. The results at 11 mg/kg/day confirm those reported from a National Toxicology Program multigenerational study which reported no observed adverse effect levels-lowest observed adverse effect levels of 5 and 10 mg/kg/day DEHP, respectively, via the diet. PMID:19482887

  7. Molecular Weight Dependent Glucose Lowering Effect of Low Molecular Weight Chitosan Oligosaccharide (GO2KA1) on Postprandial Blood Glucose Level in SD Rats Model

    PubMed Central

    Jo, Sung-Hoon; Ha, Kyoung-Soo; Moon, Kyoung-Sik; Kim, Jong-Gwan; Oh, Chen-Gum; Kim, Young-Cheul; Apostolidis, Emmanouil; Kwon, Young-In

    2013-01-01

    This research investigated the effect of enzymatically digested low molecular weight (MW) chitosan oligosaccharide on type 2 diabetes prevention. Three different chitosan oligosaccharide samples with varying MW were evaluated in vitro for inhibition of rat small intestinal α-glucosidase and porcine pancreatic α-amylase (GO2KA1; <1000 Da, GO2KA2; 1000–10,000 Da, GO2KA3; MW > 10,000 Da). The in vitro results showed that all tested samples had similar rat α-glucosidase inhibitory and porcine α-amylase inhibitory activity. Based on these observations, we decided to further investigate the effect of all three samples at a dose of 0.1 g/kg, on reducing postprandial blood glucose levels in Sprague-Dawley (SD) rat model after sucrose loading test. In the animal trial, all tested samples had postprandial blood glucose reduction effect, when compared to control, however GO2KA1 supplementation had the strongest effect. The glucose peak (Cmax) for GO2KA1 and control was 152 mg/dL and 193 mg/dL, respectively. The area under the blood glucose-time curve (AUC) for GO2KA1 and control was 262 h mg/dL and 305 h mg/dL, respectively. Furthermore, the time of peak plasma concentration of blood glucose (Tmax) for GO2KA1 was significantly delayed (0.9 h) compared to control (0.5 h). These results suggest that GO2KA1 could have a beneficial effect for blood glucose management relevant to diabetes prevention in normal and pre-diabetic individuals. The suggested mechanism of action is via inhibition of the carbohydrate hydrolysis enzyme α-glucosidase and since GO2KA1 (MW < 1000 Da) had higher in vivo effect, we hypothesize that it is more readily absorbed and might exert further biological effect once it is absorbed in the blood stream, relevant to blood glucose management. PMID:23839092

  8. On the impact of the temporal variability of the collisional quenching process on the mesospheric OH emission layer: a study based on SD-WACCM4 and SABER

    NASA Astrophysics Data System (ADS)

    Kowalewski, S.; von Savigny, C.; Palm, M.; McDade, I. C.; Notholt, J.

    2014-09-01

    The mesospheric OH Meinel emissions are subject of many theoretical and observational studies devoted to this part of the atmosphere. Depending on the initial vibrational level of excitation the altitude of the considered OH Meinel emission is systematically shifted, which has important implications for the intercomparison of different studies considering different transition bands. Previous model studies suggest that these vertical shifts are essentially caused by the process of collisional quenching with atomic oxygen. Following this hypothesis, a recent study found experimental evidence of a coherent seasonality at tropical latitudes between vertical shifts of different OH Meinel bands and changes in atomic oxygen concentrations. Despite the consistent finding of the above mentioned hypothesis, it cannot be excluded that the actual temporal variability of the vertical shifts between different OH Meinel bands may in addition be controlled or even dominated by other processes. It remains an open question whether the observed temporal evolution is indeed mainly controlled by the modulation of the collisional quenching process with atomic oxygen. By means of a sensitivity study which employs a quenching model to simulations made with the SD-WACCM4 chemistry climate model, we aim at assessing this question. From this study we find that the observed seasonality of vertical OH Meinel shifts is only partially controlled by temporal changes in atomic oxygen concentrations, while molecular oxygen has another noticeable impact on the vertical OH Meinel shifts. This in particular becomes evident for the diurnal variability of vertical OH Meinel shifts, which reveal only a poor correlation with the atomic oxygen species. Furthermore, changes in the H + O3 source gases provide another mechanism that can potentially affect the diurnal variability in addition. By comparison with limb radiance observations from the SABER/TIMED satellite this provides an explanation for the less

  9. Thermodynamic modeling of As and P incorporation In GaxIn1-xPyAs1-y epitaxial layers grown by organometallic vapor phase epitaxy

    NASA Astrophysics Data System (ADS)

    Jordan, A. S.

    1995-11-01

    The quaternary epitaxial film Gaxln1-x As1-y (Q) lattice-matched to InP is the active layer in lasers emitting between 1.1 and 1.55 μm. In this paper, we present a thermodynamic analysis of the group V incorporation in Q layers prepared by organometallic vapor phase epitaxy. We have recently given an equilibrium description of the combined pyrolysis of AsH3 and PH3 for any input flow rate and H2 dilution as a function of growth temperature and total pressure, ptot. To extend the treatment to gas-solid equilibrium, the Q solid is considered to be a quaternary regular solution subject to the constraint of mixing on both sublattices, for which activities were previously published. Knowing the free-energy of formation of the four bounding binary compounds, a root for yp at a given temperature, input flow rates and ptot is obtained by iteration that stops at values ofP_{As_4 } andP_{P_4 } simultaneously satisfying the free-energies of formation and the gas flow material balance as well as the site conservation constraint. At a constant ptot in complete thermodynamic equilibrium, yp slowly increases with temperature (800 1200K). Taking into account the incomplete decomposition of PH3 and considering the undecomposed fraction of PH3 as an “inert” gas, the analysis shows a rapid rise in yp with temperature in the deposition zone. Clearly, to attain the desirable thermodynamic regime at, say, ˜650°C, the use of an alternative source, such as tertiarybutylphosphine, is desirable. We present the solid composition, yp, as a function of temperature and PH3 flow rate for realistic parameters for Q materials emitting between 1.1 1.55 urn. We also show the predicted lattice mismatch and emission wavelength associated with yp. A preliminary comparison with experimental data obtained in our laboratory is in reasonable accord with the calculated results.

  10. Interband electronic transitions and phase transformation of multiferroic Bi1-xLaxFe1-yTiyO3 ceramics revealed by temperature-dependent spectroscopic ellipsometry

    NASA Astrophysics Data System (ADS)

    Xu, L. P.; Zhang, L. L.; Jiang, P. P.; Yu, J.; Duan, Z. H.; Hu, Z. G.; Zhu, Z. Q.; Chu, J. H.

    2013-12-01

    Optical properties and phase transition of Bi1-xLaxFe1-yTiyO3 (BLFTO) ceramics with different composition (0.02 ≤ x ≤ 0.10, 0.01 ≤ y ≤ 0.06) have been investigated by spectroscopic ellipsometry (SE) in the temperature range of -70-450 °C. The real part of the complex dielectric function ɛ1 increases with the temperature. Meanwhile, the imaginary part ɛ2 in the low-energy region decreases with the temperature and has an opposite trend in the high-energy side. Four typical interband transitions (Ea ˜ 2.50 eV, Eb ˜ 2.70 eV, Ec ˜ 3.60 eV, and Ed ˜ 4.25 eV) can be observed from the second derivative of the complex dielectric functions with aid of the standard critical point model. The critical point (CP) transition becomes broadening and shifts to a lower energy side as La and Ti compositions increase. Moreover, the CP transition energies show a red-shift trend with increasing the temperature until 320 °C, due to the lattice thermal expansion and electron-phonon interaction. The typical interband transitions and partial spectral weight present anomalies in the proximity of antiferromagnetic transition owing to the coupling between magnetic and ferroelectric order parameters and spin-lattice coupling for BLFTO multiferroic materials. It was found that the Néel temperature of BLFTO ceramics decreases from 364 to 349 °C with increasing doping composition of La and Ti elements. These phenomena can be attributed to the modification of electronic structure and magnetic order because the differences of electronegativity and ionic radii between Bi and La, Fe and Ti induce the variations on the bond angle and bond length between cations and anions. Moreover, the substitution for magnetic Fe3+ ions with nonmagnetic Ti4+ ions can reduce the exchange interaction between adjacent magnetic moments. Therefore, SE technique can be sensitive for detecting the phase/structural transitions of multiferroic oxides.

  11. Molecular approaches to p- and n-nanoscale doping of Ge 1-ySn y semiconductors: Structural, electrical and transport properties

    NASA Astrophysics Data System (ADS)

    Xie, Junqi; Tolle, J.; D'Costa, V. R.; Weng, C.; Chizmeshya, A. V. G.; Menendez, J.; Kouvetakis, J.

    2009-08-01

    We report the development of practical doping protocols via designer molecular sources to create n- and p-type doped Ge 1-ySn y layers grown directly upon Si(1 0 0). These materials will have applications in the fabrication of advanced PIN devices that are intended to extend the infrared optical response beyond that of Ge by utilizing the Sn composition as an additional design parameter. Highly controlled and efficient n-doping of single-layer structures is achieved using custom built P(GeH 3) 3 and As(GeH 3) 3, precursors containing preformed Ge-As and Ge-P near-tetrahedral bonding arrangements compatible with the structure of the host Ge-Sn lattice. Facile substitution and complete activation of the P and As atoms at levels ˜10 17-10 19 cm -3 is obtained via in situ depositions at low temperatures (350 °C). Acceptor doping is readily achieved using conventional diborane yielding carrier concentrations between 10 17-10 19 cm -3 under similar growth conditions. Full activation of the as-grown dopant concentrations is demonstrated by combined SIMS and Hall experiments, and corroborated using a contactless spectroscopic ellipsometry approach. RTA processing of the samples leads to a significant increase in carrier mobility comparable to that of bulk Ge containing similar doping levels. The alloy scattering contribution appears to be negligible for electron carrier concentrations beyond 10 19 cm -3 in n-type samples and hole concentrations beyond 10 18 cm -3 in p-type samples. A comparative study using the classical lower-order hydrides PH 3 and AsH 3 produced n-doped films with carrier densities (up to 9 × 10 19 cm -3) similar to those afforded by P(GeH 3) 3 and As(GeH 3) 3. However, early results indicate that the simpler PH 3 and AsH 3 sources yield materials with inferior morphology and microstructure. Calculations of surface energetics using bond enthalpies suggest that the latter massive compounds bind to the surface via strong Ge-Ge bonds and likely act as

  12. Improved Thermoelectric Performance of p-type Skutterudite YbxFe4-yPtySb12 (0.8 x 1, y = 1 and 0.5)

    SciTech Connect

    Cho, Jung Y; Ye, Zuxin; Tessema, Misle; Salvador, James R.; Waldo, Richard; Yang, Jiong; Zhang, Weiqing; Yang, Jihui; Cai, Wei; Wang, Hsin

    2013-01-01

    Thermoelectric performance of p-type skutterudites currently lags that of the corresponding n-type materials and improvement of this important class of materials have become the focus of considerable research effort world-wide. Recent calculations find promising band structural features in p-type skutterudite materials of the type AeFe3NiSb12 ( Ae = Ca, Sr, or Ba) which could potentially lead to excellent thermoelectric properties. Recent work on the Yb- filled analog of the these formulations (YbFe3NiSb12) however finds that the onset of intrinsic conduction at lower than expected temperatures deteriorates the performance above 500 K leading to poor performance in the temperature range of interest for automotive waste heat recovery applications. We therefore seek a way to increase the band gap in order to find a way to minimize the deleterious effects of intrinsic conduction. Here we present ab initio band structure calculations and the synthesis and thermoelectric properties of YbxFe4-yPtySb12 (0.8 x 1, y = 1 and 0.5). Ab initio calculations find that the band gap increases for YbFe3PtSb12 as compared to the Ni-containing analog, though no such increase in the band gap energy was found for as compared to YbFe3.5Ni0.5Sb12. The y = 1 samples shows a characteristic transition to intrinsic conduction with a decrease in the Seebeck coefficient at temperatures above 700 K. The increased carrier concentration in y = 0.5 virtually eliminates any evidence of intrinsic conduction and the Seebeck coefficients for these samples increase monotonically up to 750 K, resulting in power factors approaching 27 W/cm K2 at 750 K. These power factors combined with low thermal conductivity result in a ZT = 0.9 at 750 K for Yb0.95Fe3.5Pt0.5Sb12.

  13. Development of sputtering systems for large-area deposition of CuIn1-xGaxSe1-ySy thin-film solar cells

    NASA Astrophysics Data System (ADS)

    Dhere, Neelkanth G.; Gade, Vivek S.; Jahagirdar, Anant H.; Kadam, Ankur A.; Patil, Harshad P.; Kulkarni, Sachin S.

    2003-07-01

    CuIn1-xGaxSe1-ySy (CIGS) thin-film modules are expected to become cheaper than crystalline silicon modules within 5 yr. At present, commissioning and reaching full production of thin film modules is delayed because of nonavailability of turnkey manufacturing plants. Very few universities are conducting research on development of PV plants. CIGS thin-film solar cells are being prepared routinely at Florida Solar Energy Center (FSEC) on glass and metallic foil substrates for terrestrial and space applications. Earlier, the substrate size was limited to 3×3 cm2. This article presents results of development of large-area sputtering systems for preparation of large (15.2×15.2 cm2) CIGS thin-film solar cells. The facilities have the potential of serving as a nucleus of a pilot plant for fabrication of CIGS minimodules. Initial problems of bowing of the brass diaphragm, restriction of effective water flow and consequent heating of the target material were resolved by increasing the thickness of the backing plate and redesigning the structural members. Thickness uniformity was improved by modifying the magnetic field distribution in the middle 15 cm portion of the 10.2×30.5 cm2 magnetron sputtering sources by selectively removing nickel-coated soft-iron pieces at the rear. This resulted in Mo layer thickness uniformity of +/-3% over 10.2×10.2 cm2. The magnetic field was boosted at extremities to avoid precipitous ~15% drop beyond 10.2 cm. With this, thickness uniformities of +/-2.5% for Mo and +/-4.5% for ZnO over 12.7×10.2 cm2 have been achieved however with a continuing drop beyond 12.7 cm width. Modifying the magnetic field to achieve better distribution by preferentially removing soft irons pieces and also boosting of the magnetic field at the ends are two new concepts introduced and successfully utilized in this study. Scaling up of the large-area uniform deposition of metallic precursor layers was a challenging task. The efforts were directed towards obtaining

  14. Ge{sub 1-y}Sn{sub y} (y = 0.01-0.10) alloys on Ge-buffered Si: Synthesis, microstructure, and optical properties

    SciTech Connect

    Senaratne, C. L.; Kouvetakis, J.; Gallagher, J. D.; Jiang, Liying; Smith, D. J.; Menéndez, J.; Aoki, Toshihiro

    2014-10-07

    Novel hydride chemistries are employed to deposit light-emitting Ge{sub 1-y}Sn{sub y} alloys with y ≤ 0.1 by Ultra-High Vacuum Chemical Vapor Deposition (UHV-CVD) on Ge-buffered Si wafers. The properties of the resultant materials are systematically compared with similar alloys grown directly on Si wafers. The fundamental difference between the two systems is a fivefold (and higher) decrease in lattice mismatch between film and virtual substrate, allowing direct integration of bulk-like crystals with planar surfaces and relatively low dislocation densities. For y ≤ 0.06, the CVD precursors used were digermane Ge₂H₆ and deuterated stannane SnD₄. For y ≥ 0.06, the Ge precursor was changed to trigermane Ge₃H₈, whose higher reactivity enabled the fabrication of supersaturated samples with the target film parameters. In all cases, the Ge wafers were produced using tetragermane Ge₄H₁₀ as the Ge source. The photoluminescence intensity from Ge{sub 1–y}Sn{sub y}/Ge films is expected to increase relative to Ge{sub 1–y}Sn{sub y}/Si due to the less defected interface with the virtual substrate. However, while Ge{sub 1–y}Sn{sub y}/Si films are largely relaxed, a significant amount of compressive strain may be present in the Ge{sub 1–y}Sn{sub y}/Ge case. This compressive strain can reduce the emission intensity by increasing the separation between the direct and indirect edges. In this context, it is shown here that the proposed CVD approach to Ge{sub 1–y}Sn{sub y}/Ge makes it possible to approach film thicknesses of about 1 μm, for which the strain is mostly relaxed and the photoluminescence intensity increases by one order of magnitude relative to Ge{sub 1–y}Sn{sub y}/Si films. The observed strain relaxation is shown to be consistent with predictions from strain-relaxation models first developed for the Si{sub 1–x}Ge{sub x}/Si system. The defect structure and atomic distributions in the films are studied in detail using advanced electron

  15. Fluorine-ion conductivity of different technological forms of solid electrolytes R 1- y M y F3- y (LaF3 Type ) ( M = Ca, Sr, Ba; R Are Rare Earth Elements)

    NASA Astrophysics Data System (ADS)

    Sorokin, N. I.; Sobolev, B. P.

    2016-05-01

    We have investigated the conductivity of some representatives of different technological forms of fluoride-conducting solid electrolytes R 1- y M y F3- y ( M = Ca, Sr, Ba; R are rare earth elements) with an LaF3 structure: single crystals, cold- and hot-pressing ceramics based on a charge prepared in different ways (mechanochemical synthesis, solid-phase synthesis, and fragmentation of single crystals), polycrystalline alloys, etc. It is shown (by impedance spectroscopy), that different technological forms of identical chemical composition ( R, M, y) exhibit different electrical characteristics. The maximum conductivity is observed for the single-crystal form of R 1- y M y F3- y tysonite phases, which provides (in contrast to other technological forms) the formation of true volume ion-conducting characteristics.

  16. Effects of Ga- and Sb-precursor chemistry on the alloy composition in pseudomorphically strained GaAs 1-ySb y films grown via metalorganic vapor phase epitaxy

    NASA Astrophysics Data System (ADS)

    Khandekar, A. A.; Yeh, J. Y.; Mawst, L. J.; Song, Xueyan; Babcock, S. E.; Kuech, T. F.

    2007-05-01

    GaAs-based multiple quantum well (MQW) heterostructures comprised of metastable alloys such as GaAs 1-ySb y-GaAs 1-zN z have potential for realizing high-performance and low temperature-sensitivity lasers in the 1.55 μm wavelength region. However, strain-induced 'lattice-latching' and Sb-surface segregation effects limit the Sb-mole fractions in the pseudomorphically strained GaAs 1-ySb y layers to y⩽0.2. The effect of Ga- and Sb-precursor chemistry and the growth temperature on the Sb-incorporation efficiency in strain-relaxed and strained, pseudomorphic GaAs 1-ySb y films was studied using metalorganic vapor phase epitaxy. Both trimethyl- and triethyl-gallium (TMGa and TEGa) and trimethyl- and triethyl-antimony (TMSb and TESb) were used as Ga- and Sb-precursors, in four different source combinations, with arsine. The Sb-mole fraction in the strained GaAs 1-ySb y films was found to be lower than that in the relaxed films for all of the precursor chemistries. The highest Sb-incorporation rates were found with the TEGa-based growth with strained-layer compositions up to y˜0.48 being obtained for the growth conditions employed. The results were discussed in terms of the strain-related thermodynamic effects and the chemical kinetics of precursor surface decomposition for the different precursor chemistries.

  17. Method for synthesizing fine-grained phosphor powders of the type (RE.sub.1- Ln.sub.x)(P.sub.1-y V.sub.y)O.sub.4

    DOEpatents

    Phillips, Mark L. F.

    1998-01-01

    A method for generating well-crystallized photo- and cathodoluminescent oxide phosphor powders. The method of this invention uses hydrothermal synthesis and annealing to produce nearly monosized (RE.sub.1-x Ln.sub.x)(P.sub.1-y V.sub.y)O.sub.4 (Ln.dbd.Ce.fwdarw.Lu) phosphor grains with crystallite sizes from 0.04 to 5 .mu.m. Such phosphors find application in cathode-ray tube, flat-panel, and projection displays.

  18. Magnetic and chemical order-disorder transformations in Co2Fe(Ga1-xSix) and Co2Fe(Al1-ySiy) Heusler alloys

    NASA Astrophysics Data System (ADS)

    Umetsu, Rie Y.; Okubo, Akinari; Kainuma, Ryosuke

    2012-04-01

    The concentration dependence of the order-disorder phase transformation temperature from the L21 to the B2 phase (TtL21/B2) and magnetic properties of Co2Fe(Ga1-xSix) and Co2Fe(Al1-ySiy) Heusler alloys were investigated. In the phase diagrams, a crossover of the Curie temperature (TC) and TtL21/B2 was confirmed at around y = 0.45 in Co2Fe(Al1-ySiy), whereas the TC and TtL21/B2 monotonically changed with x in Co2Fe (Ga1-xSix). The slopes of the linear concentration dependence of TtL21/B2 for Co2Fe(Al1-ySiy) drastically changed at about y = 0.45, suggesting that the chemical interchange energy between Fe and Al in Co2FeAl alloy is affected by the magnetic ordering.

  19. Inoculation with endophytic Bacillus megaterium 1Y31 increases Mn accumulation and induces the growth and energy metabolism-related differentially-expressed proteome in Mn hyperaccumulator hybrid pennisetum.

    PubMed

    Zhang, Wen-hui; He, Lin-yan; Wang, Qi; Sheng, Xia-Fang

    2015-12-30

    In this study, a hydroponic culture experiment was conducted in a greenhouse to investigate the molecular and microbial mechanisms involved in the endophytic Bacillus megaterium 1Y31-enhanced Mn tolerance and accumulation in Mn hyperaccumulator hybrid pennisetum. Strain 1Y31 significantly increased the dry weights (ranging from 28% to 94%) and total Mn uptake (ranging from 23% to 112%) of hybrid pennisetum treated with 0, 2, and 10mM Mn compared to the control. Total 98 leaf differentially expressed proteins were identified between the live and dead bacterial inoculated hybrid pennisetum. The major leaf differentially expressed proteins were involved in energy generation, photosynthesis, response to stimulus, metabolisms, and unknown function. Furthermore, most of the energy generation and photosynthesis-related proteins were up-regulated, whereas most of the response to stimulus and metabolism-related proteins were down-regulated under Mn stress. Notably, the proportion of indole-3-acetic acid (IAA)-producing endophytic bacteria was significantly higher in the bacterial inoculated plants under Mn stress. The results suggested that strain 1Y31 increased the growth and Mn uptake of hybrid pennisetum through increasing the efficiency of photosynthesis and energy metabolism as well as the proportion of plant growth-promoting endophytic bacteria in the plants. PMID:26241871

  20. Effects of molecular beam epitaxy growth conditions on composition and optical properties of In{sub x}Ga{sub 1-x}Bi{sub y}As{sub 1-y}

    SciTech Connect

    Zhong, Y.; Dongmo, P. B.; Zide, J. M. O.; Petropoulos, J. P.

    2012-03-12

    We describe the growth conditions of In{sub x}Ga{sub 1-x}Bi{sub y}As{sub 1-y} (lattice-mismatched and matched) on InP substrates by molecular beam epitaxy and the resulting properties. Due to their anomalously narrow bandgaps and the presence of bismuth, these materials are promising for optoelectronics and thermoelectrics. Low growth temperature and moderate As/Bi beam equivalent pressure ratios are beneficial for Bi incorporation, in good qualitative agreement with GaBi{sub y}As{sub 1-y} on GaAs. Up to 6.75% bismuth is incorporated. High resolution x-ray diffraction and reciprocal space mapping show that In{sub x}Ga{sub 1-x}Bi{sub y}As{sub 1-y} samples exhibit good crystalline quality and zero relaxation. The band gap is reduced in agreement with theoretical predictions. Lattice-matched samples have been produced with lattice mismatch {<=}0.21%.

  1. Preparation and characterization of (1 - y)BiFeO3/y(Ba0.7Na0.3Ti0.7Nb0.3)O3 multiferroic ceramics

    NASA Astrophysics Data System (ADS)

    Jarboui, Ahmed; Bahri, Fathi; Khemakhem, Hamadi

    2013-04-01

    We present in this work a contribution to the study of the solid solution (1 - y)BiFeO3/y(Ba0.7Na0.3Ti0.7Nb0.3)O3. Room temperature X-ray diffraction patterns for some prepared compositions confirmed the formation of perovskite structure. The study of the evolution of dielectric properties as a function of sintering temperature allowed us to determine the optimum conditions that minimize the presence of defects and oxygen stoichiometric limit fluctuations due to the volatility of bismuth. The variation of permittivity as a function of temperature and frequency for the (1 - y)BiFeO3/y(Ba0.7Na0.3Ti0.7Nb0.3)O3 solid solution was measured. The effect of Ba0.7Na0.3Ti0.7Nb0.3O3 addition content on crystal structure, dielectric and magnetic properties of BiFeO3 was investigated. Raman measurements reveal resonant enhancement of two-phonon excitation for (1 - y)BiFeO3/y(Ba0.7Na0.3Ti0.7Nb0.3)O3 samples. We also expect that the solid solution shows weak ferromagnetic behavior for low Ba0.7Na0.3Ti0.7Nb0.3O3 levels of substitution.

  2. Sociological-Dysfunctionality(SD) Tyrrany-of-Arrogance((ToA) Versus (So Miscalled) ``Wisdom-of-Crowds'' Fascism; Jargonial-Obfuscation(JO) Egocentrism Enabling Would Be ``Sciences'' to be Alas Mere SEANCES!!!.

    NASA Astrophysics Data System (ADS)

    Bradshaw, John; Martin, Brian; Siegel, Edward Carl-Ludwig; Euclid, Alexandria; Young, Frederic; Clay, London; CarlZimmer/NYTimes/ReedElsevier/YoungsuckChi/Alcatel-Lucent/Thale Group/ThompsonCSF/PhalesGrope/KFAZ Collaboration; artin Correidora./Carlos Perelman Collaboration; Grigory Perelman/Richard Hamilton/Linda Naser/David Gruber Collaboration; Alexander Dewedney/Massimo Pigliucci Collaboration; Orrin Pilkey/Linda Pilkey-Jarvis/Robert Parks/Simon Levay Collaboration

    2013-03-01

    Bradshaw[''Healing Shame That Binds You'']-''Brian Martin'' SD ToA is via constant interminable media-hype spin-doctoring show-biz popularity promotion, witness ubiquitous talking-heads: ''Kuku'' sci.-guy(knows everything about everything), Green,Tyson, Alda,,,, ad infinitum, ad nauseum!!!; worse still ''scientific''-societies&apos seizing conferences/journals agendas, perverted into mere SEANCES:

  3. In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse.

    PubMed

    Máthé, Domokos; Horváth, Ildikó; Szigeti, Krisztián; Donohue, Sean R; Pike, Victor W; Jia, Zisheng; Ledent, Catherine; Palkovits, Miklós; Freund, Tamás F; Halldin, Christer; Gulyás, Balázs

    2013-02-01

    We aimed to evaluate the novel high-affinity and relatively lipophilic CB(1) receptor (CB(1)R) antagonist radioligand [(125)I]SD7015 for SPECT imaging of CB(1)Rs in vivo using the multiplexed multipinhole dedicated small animal SPECT/CT system, NanoSPECT/CT(PLUS) (Mediso, Budapest, Hungary), in knock-out CB(1) receptor knock-out (CB(1)R-/-) and wildtype mice. In order to exclude possible differences in cerebral blood flow between the two types of animals, HMPAO SPECT scans were performed, whereas in order to confirm the brain uptake differences of the radioligand between knock-out mice and wildtype mice, in vivo scans were complemented with ex vivo autoradiographic measurements using the brains of the same animals. With SPECT/CT imaging, we measured the brain uptake of radioactivity, using %SUV (% standardised uptake values) in CB(1)R-/- mice (n=3) and C57BL6 wildtype mice (n=7) under urethane anaesthesia after injecting [(125)I]SD7015 intravenously or intraperitoneally. The Brookhaven Laboratory mouse MRI atlas was fused to the SPECT/CT images by using a combination of rigid and non-rigid algorithms in the Mediso Fusion™ (Mediso, Budapest, Hungary) and VivoQuant (inviCRO, Boston, MA, USA) softwares. Phosphor imager plate autoradiography (ARG) was performed on 4 μm-thin cryostat sections of the excised brains. %SUV was 8.6±3.6 (average±SD) in CB(1)R-/- mice and 22.1±12.4 in wildtype mice between 2 and 4 h after injection (p<0.05). ARG of identically taken sections from wildtype mouse brain showed moderate radioactivity uptake when compared with the in vivo images, with a clear difference between grey matter and white matter, whereas ARG in CB(1)R(-/-) mice showed practically no radioactivity uptake. [(125)I]SD7015 enters the mouse brain in sufficient amount to enable SPECT imaging. Brain radioactivity distribution largely coincides with that of the known CB(1)R expression pattern in rodent brain. We conclude that [(125)I]SD7015 should be a useful SPECT

  4. In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse

    PubMed Central

    Máthé, Domokos; Horváth, Ildikó; Szigeti, Krisztián; Donohue, Sean R.; Pike, Victor W.; Jia, Zisheng; Ledent, Catherine; Palkovits, Miklós; Freund, Tamás F.; Halldin, Christer; Gulyás, Balázs

    2014-01-01

    We aimed to evaluate the novel high-affinity and relatively lipophilic CB1 receptor (CB1R) antagonist radioligand [125I]SD7015 for SPECT imaging of CB1Rs in vivo using the multiplexed multipinhole dedicated small animal SPECT/CT system, NanoSPECT/CTPLUS (Mediso, Budapest, Hungary), in knock-out CB1 receptor knock-out (CB1R-/-) and wildtype mice. In order to exclude possible differences in cerebral blood flow between the two types of animals, HMPAO SPECT scans were performed, whereas in order to confirm the brain uptake differences of the radioligand between knock-out mice and wildtype mice, in vivo scans were complemented with ex vivo autoradiographic measurements using the brains of the same animals. With SPECT/CT imaging, we measured the brain uptake of radioactivity, using %SUV (% standardised uptake values) in CB1R-/- mice (n = 3) and C57BL6 wildtype mice (n = 7) under urethane anaesthesia after injecting [125I]SD7015 intravenously or intraperitoneally. The Brookhaven Laboratory mouse MRI atlas was fused to the SPECT/CT images by using a combination of rigid and non-rigid algorithms in the Mediso Fusion™ (Mediso, Budapest, Hungary) and VivoQuant (inviCRO, Boston, MA, USA) softwares. Phosphor imager plate autoradiography (ARG) was performed on 4 μm-thin cryostat sections of the excised brains. %SUV was 8.6 ± 3.6 (average ± SD) in CB1R-/- mice and 22.1 ± 12.4 in wildtype mice between 2 and 4 h after injection (p < 0.05). ARG of identically taken sections from wildtype mouse brain showed moderate radioactivity uptake when compared with the in vivo images, with a clear difference between grey matter and white matter, whereas ARG in CB1R(-/-) mice showed practically no radioactivity uptake. [125I]SD7015 enters the mouse brain in sufficient amount to enable SPECT imaging. Brain radioactivity distribution largely coincides with that of the known CB1R expression pattern in rodent brain. We conclude that [125I]SD7015 should be a useful SPECT radioligand for

  5. Nonstoichiometry in inorganic fluorides: 2. Ionic conductivity of nonstoichiometric M 1 - x R xF2 + x and R 1 - y M yF3 - y crystals ( M = Ca, Sr, Ba; R are rare earth elements)

    NASA Astrophysics Data System (ADS)

    Sobolev, B. P.; Sorokin, N. I.

    2014-11-01

    The peak manifestation of nonstoichiometry in fluoride systems in the number of phases with valuable properties and wide homogeneity ranges is 45 MF2- RF3 systems, where M = Ca, Sr, Ba and R are 15 rare earth elements from La to Lu and Y (with Pm and Sc excluded). A deviation from stoichiometry in crystals of the M 1 - x R xF2 + x (CaF2 fluorite type) and R 1 - y M yF3 - y (LaF3 tysonite type) phases is responsible for the fluorine superionic conductivity σ. The range of variation in σ with changes in the qualitative ( M, R) and quantitative ( x, y) compositions in both structure types is very wide. The σ value changes by a factor of 108 in the M 1 - x R xF2 + x phases (at 500 K) and by a factor of 106 in the R 1 - y M yF3 - y phases (at 293 K). Changing compositions, one can also obtain crystals with σ values large enough for their use as fluorine-conducting solid electrolytes. Phases promising for solid electrolytes were revealed in the MFm- RFn systems ( m < n ≤ 4), which were studied within the program of searching for new multicomponent fluoride materials at the Institute of Crystallography, Russian Academy of Sciences (IC RAS). Superionic conductivity is one of the peak manifestations of the influence of defect structure of nonstoichiometric crystals on their properties. The subject of this review is the results of the studies performed at the IC RAS on the ionic conductivity of single crystals of the M 1 - x R xF2 + x and R 1 - y M yF3 - y nonstoichiometric phases.

  6. Fermi surfaces and p -d hybridization in the diluted magnetic semiconductor Ba1 -xKx(Zn1-yMny) 2As2 studied by soft x-ray angle-resolved photoemission spectroscopy

    NASA Astrophysics Data System (ADS)

    Suzuki, H.; Zhao, G. Q.; Zhao, K.; Chen, B. J.; Horio, M.; Koshiishi, K.; Xu, J.; Kobayashi, M.; Minohara, M.; Sakai, E.; Horiba, K.; Kumigashira, H.; Gu, Bo; Maekawa, S.; Uemura, Y. J.; Jin, C. Q.; Fujimori, A.

    2015-12-01

    The electronic structure of the new diluted magnetic semiconductor Ba1-xKx(Zn1-yMny )2As2 (x =0.30 , y =0.15 ) in single crystal form has been investigated by angle-resolved photoemission spectroscopy (ARPES). Measurements with soft x rays clarify the host valence-band electronic structure primarily composed of the As 4 p states. Two hole pockets around the Γ point, a hole corrugated cylinder surrounding the Γ and Z points, and an electron pocket around the Z point are observed, and explain the metallic transport of Ba1-xKx(Zn1-yMny )2As2 . This is contrasted with Ga1-xMnxAs (GaMnAs), where it is located above the As 4 p valence-band maximum (VBM) and no Fermi surfaces have been clearly identified. Resonance soft x-ray ARPES measurements reveal a nondispersive (Kondo-resonance-like) Mn 3 d impurity band near the Fermi level, as in the case of GaMnAs. However, the impurity band is located well below the VBM, unlike the impurity band in GaMnAs, which is located around and above the VBM. We conclude that, while the strong hybridization between the Mn 3 d and the As 4 p orbitals plays an important role in creating the impurity band and inducing high temperature ferromagnetism in both systems, the metallic transport may predominantly occur in the host valence band in Ba1-xKx(Zn1-yMny )2As2 and in the impurity band in GaMnAs.

  7. Analytical representation of the thermal conductivity and electrical resistivity of UC/sub 1 +- x/, PuC/sub 1-x/, and (U/sub y/Pu/sub 1-y/)C/sub 1 +- x/

    SciTech Connect

    Storms, E.K.

    1982-12-01

    This report uses selected measurements from the literature to construct analytical expressions that describe the electrical and thermal conductivity of pure, high-density UC/sub 1 +- x/, PuC/sub 1-x/, and (U/sub y/Pu/sub 1-y/C/sub 1 +- x/ as a function of x,y, and temperature. The approach shows that many of the differences between the reported measurements can be resolved if the carbon cntent of the single-phase material is taken into account. Analytical expressions are also given that describe the temperature variation of the phase boundaries for these phases. 16 figures.

  8. Experimental oxygen potentials of U1-yPryO2± x and thermodynamic assessment of the U-Pr-O system

    SciTech Connect

    McMurray, Jake W.; Silva, Chinthaka M.

    2015-12-09

    Thermogravimetric analysis (TGA) was used to determine the oxygen potentials of fluorite urania-praseodymia (U1-yPryO2± x) solid solutions for y = 0.10 and 0.20 between 1000 and 1500 °C. A thermodynamic assessment of U-Pr-O system was performed using the CALPHAD (CALculation of PHAse Diagrams) method. Furthermore, the models well reproduce the TGA measurements and the computed phase relations are in good agreement with those proposed from an X-ray diffraction investigation.

  9. The sequence complementarity between HIV-1 5' splice site SD4 and U1 snRNA determines the steady-state level of an unstable env pre-mRNA.

    PubMed Central

    Kammler, S; Leurs, C; Freund, M; Krummheuer, J; Seidel, K; Tange, T O; Lund, M K; Kjems, J; Scheid, A; Schaal, H

    2001-01-01

    HIV-1 env expression from certain subgenomic vectors requires the viral regulatory protein Rev, its target sequence RRE, and a 5' splice site upstream of the env open reading frame. To determine the role of this splice site in the 5'-splice-site-dependent Rev-mediated env gene expression, we have subjected the HIV-1 5' splice site, SD4, to a mutational analysis and have analyzed the effect of those mutations on env expression. The results demonstrate that the overall strength of hydrogen bonding between the 5' splice site, SD4, and the free 5' end of the U1 snRNA correlates with env expression efficiency, as long as env expression is suboptimal, and that a continuous stretch of 14 hydrogen bonds can lead to full env expression, as a result of stabilizing the pre-mRNA. The U1 snRNA-mediated stabilization is independent of functional splicing, as a mismatch in position +1 of the 5' splice site that led to loss of detectable amounts of spliced transcripts did not preclude stabilization and expression of the unspliced env mRNA, provided that Rev enables its nuclear export. The nucleotides capable of participating in U1 snRNA:pre-mRNA interaction include positions -3 to +8 of the 5' splice site and all 11 nt constituting the single-stranded 5' end of U1 snRNA. Moreover, env gene expression is significantly decreased upon the introduction of point mutations in several upstream GAR nucleotide motifs, which are mediating SF2/ASF responsiveness in an in vitro splicing assay. This suggests that the GAR sequences may play a role in stabilizing the pre-mRNA by sequestering U1 snRNP to SD4. PMID:11333022

  10. Suppression of HPV-16 late L1 5′-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs

    PubMed Central

    Li, Xiaoze; Johansson, Cecilia; Glahder, Jacob; Mossberg, Ann-Kristin; Schwartz, Stefan

    2013-01-01

    Human papillomavirus type 16 (HPV-16) 5′-splice site SD3632 is used exclusively to produce late L1 mRNAs. We identified a 34-nt splicing inhibitory element located immediately upstream of HPV-16 late 5′-splice site SD3632. Two AUAGUA motifs located in these 34 nt inhibited SD3632. Two nucleotide substitutions in each of the HPV-16 specific AUAGUA motifs alleviated splicing inhibition and induced late L1 mRNA production from episomal forms of the HPV-16 genome in primary human keratinocytes. The AUAGUA motifs bind specifically not only to the heterogeneous nuclear RNP (hnRNP) D family of RNA-binding proteins including hnRNP D/AUF, hnRNP DL and hnRNP AB but also to hnRNP A2/B1. Knock-down of these proteins induced HPV-16 late L1 mRNA expression, and overexpression of hnRNP A2/B1, hnRNP AB, hnRNP DL and the two hnRNP D isoforms hnRNP D37 and hnRNP D40 further suppressed L1 mRNA expression. This inhibition may allow HPV-16 to hide from the immune system and establish long-term persistent infections with enhanced risk at progressing to cancer. There is an inverse correlation between expression of hnRNP D proteins and hnRNP A2/B1 and HPV-16 L1 production in the cervical epithelium, as well as in cervical cancer, supporting the conclusion that hnRNP D proteins and A2/B1 inhibit HPV-16 L1 mRNA production. PMID:24013563

  11. Chemical synthesis of nanocrystalline BaTiO3 and Ba1-xSrxTi1-yZryO3 [(i) x = 0.03, y = 0 (ii) x = 0, y = 0.03 ] ceramics

    NASA Astrophysics Data System (ADS)

    Das, R. N.; Pramanik, P.

    2004-03-01

    Nanocrystalline BaTiO3 powders were prepared via a chemical process. This process involved the addition of aqueous barium nitrate, titanyl nitrate, triethanolamine (TEA) and sucrose to produce a homogeneous complex solution. After the complete evaporation of homogenous solution, the Ba-Ti-TEA-sucrose complex decomposed and produced black, fluffy precursor materials. The precursor materials on calcinations to 700 °C for 2 h produced nanocrystalline BaTiO3 with the corresponding average x-ray and TEM particle size {\\sim } 20 nm. BaTiO3 powders modified with SrTiO3 [Ba1-xSrxTi1-yZryO3 (x = 0.03, y = 0)] and BaZrO3 [Ba1-xSrxTi1-yZryO3 (x = 0, y = 0.03)] were also prepared using this route and investigated through x-ray diffraction and energy dispersive x-ray analysis.

  12. Enhancement of superconducting transition temperature due to antiferromagnetic spin fluctuations in iron pnictides LaFe(As1-xPx)(O1-yFy): 31P-NMR studies

    NASA Astrophysics Data System (ADS)

    Mukuda, H.; Engetsu, F.; Yamamoto, K.; Lai, K. T.; Yashima, M.; Kitaoka, Y.; Takemori, A.; Miyasaka, S.; Tajima, S.

    2014-02-01

    Systematic 31P-NMR studies on LaFe(As1-xPx)(O1-yFy) with y =0.05 and 0.1 have revealed that the antiferromagnetic spin fluctuations (AFMSFs) at low energies are markedly enhanced around x =0.6 and 0.4, respectively, and as a result, Tc exhibits respective peaks at 24 and 27 K against the P substitution for As. This result demonstrates that the AFMSFs are responsible for the increase in Tc for LaFe(As1-xPx)(O1-yFy) as a primary mediator of the Cooper pairing. From a systematic comparison of AFMSFs with a series of (La1-zYz)FeAsOδ compounds in which Tc reaches 50 K for z =0.95, we remark that a moderate development of AFMSFs causes Tc to increase up to 50 K under the condition that the local lattice parameters of the FeAs tetrahedron approach those of the regular tetrahedron. We propose that Tc of Fe-pnictides exceeding 50 K is maximized under an intimate collaboration of the AFMSFs and other factors originating from the optimization of the local structure.

  13. Theoretical consideration of magnetic phase formation in MnFeAsyP1-y and Mn2-x FexAs0.5P0.5 systems in the collective electron model

    NASA Astrophysics Data System (ADS)

    Valkov, V. I.; Golovchan, A. V.; Varyukhin, D. V.

    2012-05-01

    Experimental magnetic field dependences of magnetization in isostructural systems MnFeAsyP1-y (0.2 ≤ у ≤ 0.66) and Mn2-xFexAs0.5P0.5 (0.5 ≤ x ≤ 1.1) are analyzed by using the results of calculations from the first principles and the model approach. It is shown that the basis of the electronic mechanism of changing the type of magnetic phases in the system Mn2-xFexAs0.5P0.5 with cationic substitution is the change in the filling of the d-band. In the system MnFeAsyP1-y with anionic substitution the destabilization of the ferromagnetic phase and the occurrence of an antiferromagnetic one with decreasing the arsenic concentration can be caused by a change of the width of density of electronic states, owing to a considerable reduction of the unit-cell volume.

  14. Effects of lutein or lutein in combination with vitamin C on mRNA expression and activity of antioxidant enzymes and status of the antioxidant system in SD rats

    PubMed Central

    Song, Min-Hae; Shin, Eu-Chul; Hwang, Dae-Youn

    2015-01-01

    This study was conducted to investigate the effects of lutein alone or in combination with vitamin C on the antioxidant defense system in rats. A total of 18 eight-week-old male Sprague Dawley (SD) rats were randomly assigned to three groups for 4 weeks: control (CON), lutein (LUT, 50 mg lutein/kg BW) and lutein plus vitamin C (LVC, 50 mg lutein/kg BW+1,000 mg vitamin C/kg BW). No differences in body weight, relative live weight or plasma biochemical profiles were observed among treatment groups. In the hepatic antioxidant defense systems, the mRNA expression of superoxide dismutase (SOD) in the LUT and LVC groups was significantly (P<0.05) higher than that in the CON group, whereas the mRNA level of glutathione peroxidase (GPX), catalase (CAT) and glutathione S-transferase (GST) was not affected by the administration of antioxidants. SOD and GST activities in the LUT and LVC groups were significantly higher (P<0.05) than those in the CON group, whereas GPX, CAT and lipid peroxidation did not differ among groups. In addition, the LVC group showed a significant (P<0.05) increase in plasma and hepatic total antioxidant power (TAP) relative to the CON group. Overall, administration of lutein in combination with vitamin C improved the status of the total antioxidant defense system in SD rats. PMID:26472964

  15. Isopiestic Investigation of the Osmotic and Activity Coefficients of {yMgCl2 + (1 - y)MgSO4}(aq) and the Osmotic Coefficients of Na2SO4.MgSO4(aq) at 298.15 K

    SciTech Connect

    Miladinovic, J; Ninkovic, R; Todorovic, M; Rard, J A

    2007-06-06

    Isopiestic vapor pressure measurements were made for {l_brace}yMgCl{sub 2} + (1-y)MgSO{sub 4}{r_brace}(aq) solutions with MgCl{sub 2} ionic strength fractions of y = 0, 0.1997, 0.3989, 0.5992, 0.8008, and (1) at the temperature 298.15 K, using KCl(aq) as the reference standard. These measurements for the mixtures cover the ionic strength range I = 0.9794 to 9.4318 mol {center_dot} kg{sup -1}. In addition, isopiestic measurements were made with NaCl(aq) as reference standard for mixtures of {l_brace}xNa{sub 2}SO{sub 4} + (1-x)MgSO{sub 4}{r_brace}(aq) with the molality fraction x = 0.50000 that correspond to solutions of the evaporite mineral bloedite (astrakanite), Na{sub 2}Mg(SO{sub 4}){sub 2} {center_dot} 4H{sub 2}O(cr). The total molalities, m{sub T} = m(Na{sub 2}SO{sub 4}) + m(MgSO{sub 4}), range from m{sub T} = 1.4479 to 4.4312 mol {center_dot} kg{sup -1} (I = 5.0677 to 15.509 mol {center_dot} kg{sup -1}), where the uppermost concentration is the highest oversaturation molality that could be achieved by isothermal evaporation of the solvent at 298.15 K. The parameters of an extended ion-interaction (Pitzer) model for MgCl2(aq) at 298.15 K, which were required for an analysis of the {l_brace}yMgCl{sub 2} + (1-y)MgSO{sub 4}{r_brace}(aq) mixture results, were evaluated up to I = 12.025 mol {center_dot} kg{sup -1} from published isopiestic data together with the six new osmotic coefficients obtained in this study. Osmotic coefficients of {l_brace}yMgCl{sub 2} + (1-y)MgSO{sub 4}{r_brace}(aq) solutions from the present study, along with critically-assessed values from previous studies, were used to evaluate the mixing parameters of the extended ion-interaction model.

  16. Experimental investigation and numerical modelling of photocurrent oscillations in lattice matched Ga1-xInxNyAs1-y/GaAs quantum well p-i-n photodiodes.

    PubMed

    Royall, Ben; Khalil, Hagir; Mazzucato, Simone; Erol, Ayse; Balkan, Naci

    2014-01-01

    Photocurrent oscillations, observed at low temperatures in lattice-matched Ga1-xInxNyAs1-y/GaAs multiple quantum well (MQW) p-i-n samples, are investigated as a function of applied bias and excitation wavelength and are modelled with the aid of semiconductor simulation software. The oscillations appear only at low temperatures and have the highest amplitude when the optical excitation energy is in resonance with the GaInNAs bandgap. They are explained in terms of electron accumulation and the formation of high-field domains in the GaInNAs QWs as a result of the disparity between the photoexcited electron and hole escape rates from the QWs. The application of the external bias results in the motion of the high-field domain towards the anode where the excess charge dissipates from the well adjacent to anode via tunnelling. PMID:24548551

  17. Effect of on band alignment of compressively strained Ga 1- xIn xN y As 1- y- zSb z/GaAs quantum well structures

    NASA Astrophysics Data System (ADS)

    Aissat, A.; Nacer, S.; Seghilani, M.; Vilcot, J. P.

    2010-11-01

    In this paper, we provide a systematic investigation of the band alignment of quinary GaInNAsSb alloy based quantum wells, starting from the simplest ternary GaInAs compound to the new quinary GaInNAsSb one. We calculate the band gap and the band discontinuities of Ga 1- xIn xN y As 1- y- zSb z structures, using band anticrossing (BAC) models applied simultaneously to conduction and valence band. Nitrogen and antimony concentrations leading to an emission wavelength of 1.6 μm have been determined ( x=38%, y=2%, z=4%). This structure shows a good electron confinement resulting in a high characteristic temperature. GaInNAsSb has been found to be a potentially superior material to both InGaAsP and GaInNAs for communication wavelength laser applications.

  18. A model for the spectral blueshift caused by the In-N clusters in InxGa1-xNyAs1-y (x<0.4 and y≤0.04) after annealing

    NASA Astrophysics Data System (ADS)

    Zhao, Chuan-Zhen; Li, Na-Na; Wei, Tong; Wang, Sha-Sha; Lu, Ke-Qing

    2013-07-01

    A model describing the spectral blueshift of the quaternary alloy InxGa1-xNyAs1-y (x<0.4 and y≤0.04) caused by the In-N clusters after annealing is developed by modifying the band-anticrossing (BAC) model. In the modified BAC model, we consider the effect of the added In-N clusters after annealing on the parameters in the band anticrossing model. It is found that the variation of the N level can be considered to be proportional to the variation of the average number of the nearest-neighbor In atoms per N atom, and the variation of the coupling interaction between the N level and the Γ conduction band is determined by the added In-N bonds and the In content. The obtained results are in agreement well with the experimental data. It is very helpful to explain the essence of the blueshift caused by annealing.

  19. Crystal structure, magnetic and infrared spectroscopy studies of the LiCr{sub y}Fe{sub 1-y}P{sub 2}O{sub 7} solid solution

    SciTech Connect

    Bih, Hssain; Saadoune, Ismael; Ehrenberg, Helmut; Fuess, Hartmut

    2009-04-15

    The lithium double diphosphates LiCr{sub y}Fe{sub 1-y}P{sub 2}O{sub 7} have been investigated by X-ray diffraction, SQUID measurements and vibrational spectroscopy. The Rietveld refinements based on the XRD patterns show the existence of a continuous solid solution over the whole composition range (0<=y<=1.0) with a continuous evolution of the monoclinic unit cell parameters (S.G. P2{sub 1}). The transition metal ions connect the diphosphate anions forming a three-dimensional network with channels filled by Li{sup +} cations expected to exhibit high mobility. All compounds order magnetically at low temperatures due the Fe-Fe interactions. The ordering temperature decreases with increasing Cr content. The slope in Curie-Weiss fits to the 1/chi vs T data in the paramagnetic domain clearly shows the existence of Fe{sup 3+} and Cr{sup 3+} in their high spin states, and a ferromagnetic component is clearly detected for y=0, 0.2 and 0.4. IR spectra have been interpreted using factor group analysis. The small shift of the frequencies is due to the influence of the chromium amount. The POP angles were estimated using the Lazarev's relationship. - Graphical abstract: Crystal structure of LiCr{sub y}Fe{sub 1-y}P{sub 2}O{sub 7} diphosphates, view along the 'a' axis. Red circles denote the lithium atoms. For interpretation of this figure legend, the reader is referred to the web version of this article.

  20. Single-Step Synthesis of FeSO4F1-yOHy (0 ≤ y ≤ 1) Positive Electrodes for Li-Based Batteries

    SciTech Connect

    Ati, M; Sougrati, M-T; Rousse, G; Recham, N; Doublet, M-L; Jumas, J-C; Tarascon, J-M

    2012-05-29

    The recent discovery of electrochemical activity at 3.6 V vs Li+/Li0 in LiFeSO4F has generated widespread research activity in this new family of fluorosulfate electrode materials aiming at either increasing the Fe3+/Fe2+ redox potential, searching for new active members, or extending this family to hydroxyl-fluorosulfates. Here we present a new low temperature single step synthesis of FeSO4F1-yOHy phases using FeF3 and Fe2(SO4)3 ∙ nH2O as precursors. Using thorough chemical analytical techniques to test for F- content in conjunction with Moessbauer measurements, we demonstrate the existence of a limited solid solution (0.35 < y < 1) within this system. Members pertaining to this solid solution have a redox activity ranging from 3.2 to 3.6 V vs Li+/Li0 and show sustained reversible capacity retention of 130 mAh/g which makes them potentially interesting for Li-based polymer batteries. We demonstrate that the Li-insertion-deinsertion mechanism depends markedly on the sample F- content by using joint in situ XRD and Moessbauer spectroscopy. Moreover, we show the versatility of our synthetic approach by extending it to the elaboration of Fe1-zMzSO4F1-yOHy phases with M = Ti and V.

  1. Alloying of GaNxAs1-x with InNxAs1-x: A simple formula for the band gap parametrization of Ga1-yInyNxAs1-x alloys

    NASA Astrophysics Data System (ADS)

    Kudrawiec, R.

    2007-01-01

    It has been shown that the band gap energy of dilute nitride ternary alloys (Ga1-yInyNxAs1-x in this case) can be predicted by knowing the band gap energy for dilute nitride binary alloys (GaNxAs1-x and InNxAs1-x alloys in this case) and a bowing parameter. The band gap energy for GaNxAs1-x and InNxAs1-x can be calculated after the band anticrossing (BAC) model [W. Shan et al., Phys. Rev. Lett. 82, 1221 (1999)] or other formula, whereas the bowing parameter can be assumed to be the same as for the GaInAs alloy. This approach does not require the BAC parameters related to Ga1-yInyNxAs1-x and can be applied for other dilute nitride ternary alloys. The obtained band gap predictions are in good agreement with available experimental data for as-grown GaInNAs materials. It means that the proposed energy gap parametrization corresponds to the random environment of N atoms by Ga and In atoms since alloying of GaNxAs1-x with InNxAs1-x also corresponds to alloying of Ga-rich environment of N atoms (which is expected for the as-grown GaInNAs material with low indium content) with In-rich environment of N atoms (which is expected for the as-grown GaInNAs material with high indium content).

  2. Muon spin relaxation study of the Cu spin dynamics in electron-doped high- Tc superconductor Pr0.86LaCe0.14Cu1-yZnyO4

    NASA Astrophysics Data System (ADS)

    Risdiana; Adachi, T.; Oki, N.; Koike, Y.; Suzuki, T.; Watanabe, I.

    2010-07-01

    Muon-spin-relaxation (μSR) measurements have been performed for the partially Zn-substituted electron-doped high- Tc superconductor Pr0.86LaCe0.14Cu1-yZnyO4+α-δ with y=0-0.05 and the reduced oxygen content δ=0-0.09 , in order to investigate nonmagnetic Zn-impurity effects on the Cu-spin dynamics. For all the measured samples with 0.01≤δ≤0.09 , it has been found that a fast depolarization of muon spins is observed below 100 K due to the effect of Pr3+ moments and that the μSR time spectrum in the long-time region above 5μsec increases with decreasing temperature at low temperatures below 30 K possibly due to slowing down of the Cu-spin fluctuations assisted by Pr3+ moments. No Zn-induced slowing down of the Cu-spin fluctuations has been observed for moderately oxygen-reduced samples with 0.04≤δ≤0.09 , which is very different from the μSR results of La2-xSrxCu1-yZnyO4 . The possible reason may be that there are no dynamical stripe correlations of spins and electrons in the electron-doped high- Tc cuprates or that the effect of Pr3+ moments on the μSR spectra is stronger than that of a small amount of Zn impurities.

  3. Structural properties and application in lithium cells of Li(Ni0.5Co0.5)1-yFeyO2 (0 ≤ y ≤ 0.25) prepared by sol-gel route: Doping optimization

    NASA Astrophysics Data System (ADS)

    Abdel-Ghany, A. E.; Hashem, A. M.; Elzahany, E. A.; Abuzeid, H. A.; Indris, S.; Nikolowski, K.; Ehrenberg, H.; Zaghib, K.; Mauger, A.; Julien, C. M.

    2016-07-01

    Layered Li(Co0.5Ni0.5)1-yFeyO2 (0.0 ≤ y ≤ 0.25) oxides were prepared by citric-acid assisted sol-gel method. Elemental and structural properties were investigated by energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), Raman scattering (RS) and Mössbauer spectroscopy, and magnetometry. EDX images show a homogeneous distribution of Fe ions. XRD and RS spectroscopy reveal that the materials crystallize as a LiNiO2sbnd LiCoO2sbnd LiFeO2 solid solution with the typical rhombohedral α-NaFeO2 structure (R 3 bar m S.G.) up to y = 0.2 at which composition a secondary phase was observed. For y > 0.2 the XRD results show the appearance of the α-LiFeO2 phase with the cubic structure (Fm3m S.G.). The degree of cation mixing investigated by XRD analysis and magnetic measurements is z < 0.04, for y < 0.2. Electrochemical tests of Li(Co0.5Ni0.5)1-yFeyO2 (0.0 ≤ y ≤ 0.1) oxides in lithium cells show the influence of iron substitution. The best results have been obtained for the composition y(Fe) = 0.05, where the electrical conductivity is maximum. A specific capacity 32 mAh g-1 is maintained at 8C rate.

  4. Disproportionation and thermochemical sulfate reduction reactions in S-H20-Ch4 and S-D2O-CH4 systems from 200 to 340 °C at elevated pressures

    USGS Publications Warehouse

    Yuan, Shunda; Chou, I-Ming; Burruss, Robert A.

    2013-01-01

    Elemental sulfur, as a transient intermediate compound, by-product, or catalyst, plays significant roles in thermochemical sulfate reduction (TSR) reactions. However, the mechanisms of the reactions in S-H2O-hydrocarbons systems are not clear. To improve our understanding of reaction mechanisms, we conducted a series of experiments between 200 and 340 °C for S-H2O-CH4, S-D2O-CH4, and S-CH4-1m ZnBr2 systems in fused silica capillary capsules (FSCC). After a heating period ranging from 24 to 2160 hours (hrs), the quenched samples were analyzed by Raman spectroscopy. Combined with the in situ Raman spectra collected at high temperatures and pressures in the S-H2O and S-H2O-CH4 systems, our results showed that (1) the disproportionation of sulfur in the S-H2O-CH4 system occurred at temperatures above 200 °C and produced H2S, SO42-, and possibly trace amount of HSO4-; (2) sulfate (and bisulfate), in the presence of sulfur, can be reduced by methane between 250 and 340 °C to produce CO2 and H2S, and these TSR temperatures are much closer to those of the natural system (2O-CH4 system may take place simultaneously, with TSR being favored at higher temperatures; and (4) in the system S-D2O-CH4, both TSR and the competitive disproportionation reactions occurred simultaneously at temperatures above 300 °C, but these reactions were very slow at lower temperatures. Our observation of methane reaction at 250 °C in a laboratory time scale suggests that, in a geologic time scale, methane may be destroyed by TSR reactions at temperatures > 200 °C that can be reached by deep drilling for hydrocarbon resources.

  5. SD Bioline malaria antigen Pf (HRP-2/pLHD) for assessing efficacy of artemisinin combination therapy against Plasmodium falciparum in pediatric patients in the Democratic Republic of the Congo

    PubMed Central

    Kilauzi, Albert Lukuka; Mulumba, Jose Gaby Tshikuka; Magafu, Mgaywa Gilbert Mjungu Damas; Matchaba-Hove, Reginald; Tapera, Roy; Magafu, Naoko Shimizu; Tamfum, Jean Jacques Muyembe

    2015-01-01

    Introduction The emergence of Plasmodium falciparum resistance to artemisinin combination therapy (ACT) is a worrying development. It calls for close surveillance to monitor the efficacy of the drugs. The objectives of this study were to determine the performance of SD Bioline malaria AgPf(HRP-2/pLDH) 3 band Rapid Diagnostic Test (RDT) against Giemsa-stained blood smear and evaluate the suitability of this test in assessing the therapeutic efficacy of ACT in pediatric malaria patients in the Democratic Republic of the Congo (DRC). Methods Five hundred and one patients with malaria symptoms were screened for P. falciparum in Kinshasa, DRC. Of the 166 patients who tested positive for P. falciparum at recruitment (day 0), 103 consented to participate in this study and were followed up and retested for P. falciparum on day 3, day 7, day 14, day 21 and day 28. Results Sensitivity and specificity of the test were significantly high on day 0 and so were their positive and negative predictive values. Higher proportions of false positive cases were observed on the HRP-2 band irrespective of patient parasite densities during the follow up but these were barely seen on the pLDH band. Some patients turned positive during follow up but pLDH readings remained consistent with blood smear readings. Conclusion SD Bioline malaria AgPf(HRP-2/pLDH) RDT demonstrated high performance in DRC. Thus, the test can be employed to assess the efficacy of ACT in pediatric malaria patients and prioritize areas that require the deployment of advanced testing like polymerase chain reaction (PCR). PMID:26966500

  6. Helping Children Outgrow War. SD Technical Paper.

    ERIC Educational Resources Information Center

    Miller, Vachel W.; Affolter, Friedrich W.

    Helping children outgrow war is an overarching goal of educational reconstruction in post-conflict settings, but responses must be highly adaptive and informed by insights gained from interventions elsewhere. This guidebook offers seven examples of successful interventions in post-conflict settings internationally, situating them within a…

  7. SD-4060OCPLT4 program, user's guide

    NASA Technical Reports Server (NTRS)

    Glazer, J.

    1973-01-01

    A brief description of the Orbit Comparison Plot (OCPLT4) program is presented, along with user information and a source program listing. In addition to correcting several errors that existed in the original program, this program incorporates the following new features: (1) For any satellite whose observations are processed by the Definitive Orbit Determination System (DODS), the orbital uncertainty estimates (OUE) can be obtained via appropriate card input with no major modification to the program. (2) All satellite-related information (e.g., plotter scales, cutoff limits, plotting frequencies) is user controlled via card input. (3) Not all components of OUE must be obtained. The user has the option of obtaining only the radial component if there is no need for the other two components. (4) The altitude and time graph formats are controlled by the user and are not stored for specific satellites.

  8. Postscript: SD-Squared Revisited Again

    ERIC Educational Resources Information Center

    Woollams, Anna M.; Lambon Ralph, Matthew A.; Plaut, David C.; Patterson, Karalyn

    2010-01-01

    The current authors reply to a postscript by Coltheart, Tree, and Saunders which was in response to the current authors response on a comment by the current authors on the original article. The current authors begin by responding to the final challenge posed by Coltheart, Tree, and Saunders (2010). They believe that both experimental and…

  9. SOYBEAN.APHID.2.SD.2011

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soybean aphid (SA, Aphis glycines Matsumura) has been an important pest of soybean (Glycine max (L.) Merr.) in the United States since 2000. Identification and genetic characterization of SA resistance in early maturing soybean germplasm will facilitate development of aphid-resistant cultivars in no...

  10. Resonances in s-d shell nuclei

    SciTech Connect

    Schiffer, J.P.

    1981-01-01

    It appears that the system we have studied here, /sup 24/Mg(/sup 16/O,/sup 12/C)/sup 28/Si representing /sup 40/Ca as the composite nucleus, is perhaps the heaviest one that exhibits strong enough resonances that quantitative measurements may be contemplated. But we have uncovered only a small corner of what is there and even within this system a huge amount of work remains. The nature of these resonances is not yet clear. The sequence may perhaps have an explanation that is schematically outlined, namely that there are several families of quasistationary states in /sup 40/Ca, but that the slopes of these families do not necessarily coincide with the slope of the grazing partial waves that provide us with a narrow transparent strip of a window on the underlying structure of the nucleus. We must concentrate a lot of effort and ingenuity in order to maximize the information we gather through this window and only then may we hope to sensibly attempt forming hypotheses about the underlying simple pattern.

  11. SOYBEAN.DEFOLIATION.1.SD.2011

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Various chewing insects feed upon soybean plants, and their infestations may be economically significant in some years in the north-central United States. Soybean lines that are resistant to defoliation may be useful for management of chewing insect pests. Levels of defoliation from chewing insec...

  12. SOYBEAN.DEFOLIATION.2.SD.2011

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Several types of chewing insects feed upon soybean plants, and their infestations may be economically significant in some years in the north-central United States. Soybean lines that are resistant to defoliation may be useful in the management of chewing insect pests. Levels of defoliation from c...

  13. Final Report, SD-265; Project TACT.

    ERIC Educational Resources Information Center

    Air Force Systems Command, L.G. Hanscom Field, MA. Electronic Systems Div.

    The project objective has been to determine what creative thought processes can best take advantage of new technology in computer hardware and software. The plan has been to acquire or develop on-line computer systems of significant mathematical power, and to explore their use in vivo in teaching and research situations. The main product of…

  14. Local structure in the Li-ion battery cathode material Li x(Mn yFe 1- y)PO 4 for 0 < x ≤ 1 and y = 0.0, 0.5 and 1.0

    NASA Astrophysics Data System (ADS)

    Burba, Christopher M.; Frech, Roger

    Infrared and Raman spectroscopy have been used to investigate the Li-ion battery cathode materials Li x(Mn yFe 1- y)PO 4 for 0 < x ≤ 1 and y = 0.0, 0.5 and 1.0. In the Raman spectrum of Li(Mn 0.5Fe 0.5)PO 4, the frequency of the P O43- symmetric stretching mode is very similar to that found in LiFePO 4 and LiMnPO 4, suggesting that the P-O bond lengths are similar across the entire Li(Mn yFe 1- y)PO 4 solid-solution series. The more localized ν 1 and ν 3 bands (symmetric and antisymmetric P O43- stretching modes, respectively) in the infrared spectra exhibit two-mode behavior for all three Li(Mn yFe 1- y)PO 4 compositions studied, whereas the P O43- antisymmetric bending modes (ν 4) and the Li + cage mode frequencies vary with Mn 2+ concentration. The vibrational modes in Li x(Mn 0.5Fe 0.5)PO 4 are sensitive to lithium content (x) and are, thus, used to investigate changes in the (Mn 0.5Fe 0.5)PO 4 framework under cycling. The lack of spectral changes during the Fe 2+/Fe 3+ redox couple (3.7 V versus Li +/Li) suggests that the P O43- anions have similar local environments in Li(Mn 0.5 (II)Fe 0.5 (II))PO 4 and Li 0.5(Mn 0.5 (II)Fe 0.5 (III))PO 4. Two-phase behavior is confirmed during the Mn 2+/Mn 3+ redox couple (4.2 V), and the infrared spectrum for (Mn 0.5 (III)Fe 0.5 (III))PO 4 is similar to that of FePO 4 since both phases contain P O43- anions coordinated only to trivalent transition metal ions. However, the P O43- anions are much more distorted in (Mn 0.5 (III)Fe 0.5 (III))PO 4 compared to FePO 4, probably as a result of deformation of the MnO 6 octahedra induced by Jahn-Teller active Mn 3+ ions in the (Mn 0.5 (III)Fe 0.5 (III))PO 4 structure. Raman spectra suggest that the carbon layer coating the Li(Mn 0.5Fe 0.5)PO 4 particles (to improve electronic contact between particles) is predominantly composed of sp 2-hybridized carbon atoms.

  15. Investigation of upconversion and downconversion fluorescence emissions from β-NaLn1F{sub 4}:Yb{sup 3+}, Ln2{sup 3+} (Ln1 = Y, Lu; Ln2 = Er, Ho, Tm, Eu) hexagonal disk system

    SciTech Connect

    He, Enjie; Zheng, Hairong; Gao, Wei; Tu, Yinxun; Lu, Ying; Li, Guian

    2013-09-01

    Graphical abstract: Well-defined β-NaLn1F4:Yb{sup 3+}, Ln2{sup 3+} (Ln1 = Y, Lu; Ln2 = Er, Ho, Tm, Eu) hexagonal thin disks with a simple and user-friendly hydrothermal approach by using sodium citrate as a shape modifier. Much stronger UC and DC fluorescence emissions were observed in NaLuF{sub 4}-based hexagonal disks than that for NaYF{sub 4} counterparts. The strength of hypersensitive transitions is mainly attributed to the decrease of local symmetry Ln-F bond lengths in β-NaLuF{sub 4}. It will show a great potential in improving near-infrared conversion efficiency of silicon solar cells and removable sub-micro luminescent platforms. - Highlights: • Regular hexagonal disks (NaLnF{sub 4}) were synthesized by a simple hydrothermal method. • Much stronger UC and DC emissions were observed in NaLuF{sub 4}-based disks. • Stronger fluorescence emissions in NaLuF{sub 4}-based disks were explained reasonably. • NaLuF{sub 4}-based disks can act as a removable luminescent platform for nano-assembly. • NaLuF{sub 4}-based disks can be applied in improving efficiency of solar cells. - Abstract: Uniform hexagonal β-NaLn1F{sub 4}:Yb{sup 3+}, Ln2{sup 3+} (Ln1 = Y, Lu; Ln2 = Er, Ho, Tm, Eu) disks were synthesized with hydrothermal method in which the sodium citrate was used as a shape modifier. The experimental observation indicated that both upconversion and downconversion fluorescence emissions were significantly stronger in β-NaLuF{sub 4} than that for β-NaYF{sub 4}. It was found that the stronger hypersensitive transitions were mainly due to the increase of J–O parameter (Ω{sub 2}) in β-NaLuF{sub 4} host, while the stronger insensitive transitions were mainly caused by the stronger overlap of electron cloud that was induced by the decrease of Ln-F bond lengths. Additionally, the larger absorption strength in the near-infrared region is another important factor for the stronger fluorescence emissions. The current research has a great potential in

  16. Approved IFCC recommendation on reporting results for blood glucose: International Federation of Clinical Chemistry and Laboratory Medicine Scientific Division, Working Group on Selective Electrodes and Point-of-Care Testing (IFCC-SD-WG-SEPOCT).

    PubMed

    D'Orazio, Paul; Burnett, Robert W; Fogh-Andersen, Niels; Jacobs, Ellis; Kuwa, Katsuhiko; Külpmann, Wolf R; Larsson, Lasse; Lewenstam, Andrzej; Maas, Anton H J; Mager, Gerhard; Naskalski, Jerzy W; Okorodudu, Anthony O

    2006-01-01

    In current clinical practice, plasma and blood glucose are used interchangeably with a consequent risk of clinical misinterpretation. In human blood, glucose is distributed, like water, between erythrocytes and plasma. The molality of glucose (amount of glucose per unit water mass) is the same throughout the sample, but the concentration is higher in plasma, because the concentration of water and therefore glucose is higher in plasma than in erythrocytes. Different devices for the measurement of glucose may detect and report fundamentally different quantities. Different water concentrations in the calibrator, plasma, and erythrocyte fluid can explain some of the differences. Results for glucose measurements depend on the sample type and on whether the method requires sample dilution or uses biosensors in undiluted samples. If the results are mixed up or used indiscriminately, the differences may exceed the maximum allowable error for glucose determinations for diagnosing and monitoring diabetes mellitus, thus complicating patient treatment. The goal of the International Federation of Clinical Chemistry and Laboratory Medicine, Scientific Division, Working Group on Selective Electrodes and Point of Care Testing (IFCC-SD-WG-SEPOCT) is to reach a global consensus on reporting results. The document recommends reporting the concentration of glucose in plasma (in the unit mmol/L), irrespective of sample type or measurement technique. A constant factor of 1.11 is used to convert concentration in whole blood to the equivalent concentration in plasma. The conversion will provide harmonized results, facilitating the classification and care of patients and leading to fewer therapeutic misjudgments. PMID:17163827

  17. Increased Locomotor Activity and Non-Selective Attention and Impaired Learning Ability in SD Rats after Lentiviral Vector-Mediated RNA Interference of Homer 1a in the Brain

    PubMed Central

    Hong, Qin; Yang, Lei; Zhang, Min; Pan, Xiao-Qin; Guo, Mei; Fei, Li; Tong, Mei-Ling; Chen, Rong-Hua; Guo, Xi-Rong; Chi, Xia

    2013-01-01

    Our previous studies found that Homer 1a, a scaffolding protein localized at the post-synaptic density (PSD) of glutamatergic excitatory synapses, is significantly down-regulated in the brain of spontaneous hypertensive rats (SHR), an animal model of attention deficit hyperactivity disorder (ADHD). Furthermore, a first-line treatment drug for ADHD, methylphenidate, can up-regulate the expression of Homer 1a. To investigate the possible role of Homer 1a in the etiology and pathogenesis of ADHD, a lentiviral vector containing miRNA specific for Homer 1a was constructed in this study. Intracerebroventricular injection of this vector into the brain of Sprague Dawley (SD) rats significantly decreased Homer 1a mRNA and protein expression levels. Compared to their negative controls, these rats displayed a range of abnormal behaviors, including increased locomotor activity and non-selective attention and impaired learning ability. Our results indicated that Homer 1a down-regulation results in deficits in control over behavioral output and learning similar to ADHD. PMID:23289010

  18. Characterization of optical and crystal qualities in In xGa 1- xN/In yGa 1- yN multi-quantum wells grown by MOCVD

    NASA Astrophysics Data System (ADS)

    Lee, Sung-Nam; Sakong, Tan; Lee, Wonseok; Paek, Hosun; Seon, Moonsuk; Lee, In-Hwan; Nam, Okhyun; Park, Yongjo

    2003-03-01

    We have investigated the optical and structural qualities of In xGa 1- xN/In yGa 1- yN multi-quantum wells (MQWs) on sapphire substrates using atomic force microscope (AFM), high resolution X-ray diffraction (HRXRD), and photoluminescence (PL). In 0.08Ga 0.92N/ In 0.02Ga 0.98N five MQWs were grown by metalorganic chemical vapor deposition with three different well growth rates. We found from HRXRD and AFM that the interface roughness of MQWs was improved and the density of threading dislocation with screw component was decreased from 1.2×10 9/cm 2 to 2.5×10 7/cm 2 with decreasing the growth rate. Moreover, PL measurements revealed that the MQWs grown with a lower growth rate represented higher PL intensity, narrower line width and less energy shift in power dependent PL. This implies that lower growth rate allows adatoms on the surface to have longer time to arrive at two-dimensional step ledges of growth front and thereby enhances crystal quality compared with higher growth rate, leading to enhanced optical and crystal quality of MQWs.

  19. Pressure effect on the magnetism of the diluted magnetic semiconductor (B a1 -xKx ) (Zn1-yM ny ) 2A s2 with independent spin and charge doping

    NASA Astrophysics Data System (ADS)

    Sun, F.; Li, N. N.; Chen, B. J.; Jia, Y. T.; Zhang, L. J.; Li, W. M.; Zhao, G. Q.; Xing, L. Y.; Fabbris, G.; Wang, Y. G.; Deng, Z.; Uemura, Y. J.; Mao, H. K.; Haskel, D.; Yang, W. G.; Jin, C. Q.

    2016-06-01

    We used x-ray magnetic circular dichroism (XMCD) to probe the ferromagnetic properties of As p -symmetric (4 p ) states in the recently synthesized diluted magnetic semiconductor (B a1 -xKx) (Zn1-yM ny) 2A s2 system under ambient- and high-pressure conditions. The As K -edge XMCD signal scales with the sample magnetization (dominated by Mn) and scales with the ferromagnetic ordering temperature T c , and hence it is representative of the bulk magnetization. The XMCD intensity gradually decreases upon compression and vanishes at around 25 GPa, indicating quenching of ferromagnetism at this pressure. Transport measurements show a concomitant increase in conductivity with pressure, leading to a nearly metallic state at about the same pressure where magnetic order collapses. High-pressure x-ray diffraction shows an absence of structural transitions to 40 GPa. The results indicate that the mobility of doped holes, probed by both transport and x-ray absorption spectroscopy (4 p band broadening), is intimately connected with the mechanism of magnetic ordering in this class of compounds and that its control using external pressure provides an alternative route for tuning the magnetic properties in diluted magnetic semiconductor materials.

  20. First Principles Calculations of Oxygen Vacancy Formation and Migration in Ba1-xSrxCo1-yFeyO3-δ Perovskites

    SciTech Connect

    Merkle, Rotraut; Mastrikov, Yuri A.; Kotomin, Eugene A.; Kuklja, Maija M.; Maier, Joachim

    2012-01-01

    Based on first principles DFT calculations, we analyze oxygen vacancy formation and migration energies as a function of chemical composition in complex multicomponent (Ba,Sr)(Co,Fe)O3-δ perovskites which are candidate materials for SOFC cathodes and permeation membranes. The atomic relaxation, electronic charge redistribution and energies of the transition states of oxygen migration are compared for several perovskites to elucidate the atomistic reason for the exceptionally low migration barrier in Ba0.5Sr0.5Co0.8Fe0.2O3-δ that was previously determined experimentally. The critical comparison of Ba1-xSrxCo1-yFeyO3-δ perovskites with different cation compositions and arrangements shows that in addition to the geometric constraints the electronic structure plays a considerable role for the height of the oxygen migration barrier in these materials. These findings help understand advantages and limitations of the fast oxygen permeation and exchange properties of Ba0.5Sr0.5Co0.8Fe0.2O3-δ.

  1. Luminescent spectroscopy and structural properties of Ce3+-doped low-temperature X1-Y2SiO5 material prepared by polymer-assisted sol-gel method

    NASA Astrophysics Data System (ADS)

    Hamroun, M. S. E.; Guerbous, L.; Bensafi, A.

    2016-04-01

    Cerium (Ce3+)-doped monoclinic X1-Y2SiO5 (YSO)-type oxyorthosilicates powders were prepared by monomer and polymer-assisted sol-gel method. The present work aims to study the influence of ethylene glycol (EG) monomer, polyethylene glycol (PEG) polymer and polyvinyl alcohol (PVA) polymer, as fuels and nucleating agents for the crystallization, on structural and luminescence properties of the Ce3+ (xCe = 0.01)-doped Y2SiO5. The X-ray diffraction technique, field emission scanning electron microscopy, Fourier transform infrared spectroscopy and steady photoluminescence have been used to characterize the samples. It is found that the types of fuels affect the phase purity and luminescent characteristics of phosphors. All samples exhibit intense violet-blue asymmetric emission band in the range of 370-540 nm with a maximum intensity centered at around 420 nm assigned to the 5d → 4f (2F5/2, 2F7/2) interconfigurational transitions of Ce3+ ion in YSO nanomaterial. Finally, the vibronic coupling parameters are estimated and discussed.

  2. Improvement of (Pb1-xLax)(ZryTi1-y)1-x/4O3 ferroelectric thin films by use of SrRuO3/Ru/Pt/Ti bottom electrodes

    NASA Astrophysics Data System (ADS)

    Liu, Kuo-Shung; Tseng, Tzu-Feng; Lin, I.-Nan

    1998-03-01

    This work deposits (Pb1-xLax)(ZryTi1-y)1-x/4O3 (PLZT) thin films, possessing good ferroelectric properties (Pr=14.4 μC/cm2), on Pt/Ti/SiO2/Si substrates, using SrRuO3 perovskite as bottom electrodes. Precoating a metallic Ru layer on Pt/Ti/SiO2/Si substrates prior to depositing SrRuO3 bottom electrode further improves the film electrical properties. The optimum ferroelectric properties achieved are Pr=25.6 μC/cm2, Ec=47.1 kV/cm, and ɛr=1204. Analyzing the elemental depth profiles using secondary ions mass spectroscopy reveals that the presence of the metallic Ru layer effectively suppresses the outward diffusion of Ti and Si species. The interdiffusion between the SrRuO3 layer and the subsequently deposited PLZT is also substantially reduced, an effect that is presumed to be the primary factor in improving ferroelectric properties for PLZT thin films.

  3. Crystal structure of new Li + ion conducting perovskites: Li 2 xCa 0.5- xTaO 3 and Li 0.2[Ca 1- ySr y] 0.4TaO 3

    NASA Astrophysics Data System (ADS)

    Pham, Quoc Nghi; Crosnier-Lopez, Marie-Pierre; Le Berre, Françoise; Fauth, François; Fourquet, Jean-Louis

    2004-09-01

    Two new solid solutions—Li 2 xCa 0.5- xTaO 3 (0.05⩽ x⩽0.25) and Li 0.2[Ca 1- ySr y] 0.4TaO 3 (0< y⩽0.15)—based on the A defective ABO 3 perovskite structural type, are synthesized. The crystal structures of these Li + ion conducting compounds are solved from synchrotron radiation and conventional X-ray powder diffraction data. The unit cells exhibit a classical orthorhombic distortion of the cubic perovskite model (space group Pnma No. 62) with parameters close to 2a p, 2 ap, 2a p ( ap, primitive cubic cell parameter). The distortion of the cubic aristotype arises from the three tilts system a+b-b- of the TaO 6 octahedra. For the same lithium content ( x=0.10), the Sr 2+ substitution to Ca 2+ is found to enhance the electrical conductivity by quasi-one order of magnitude (at 200 °C, bulk dc conductivity values are close to 2.3×10 -6 and 1.1×10 -5 S cm -1 for Li 0.2Ca 0.4TaO 3 and Li 0.2[Ca 0.9Sr 0.1] 0.4TaO 3, respectively).

  4. Direct Observation of Lattice Aluminum Environments in Li Ion Cathodes LiNi1-y-zCoyAlzO2 and Al-Doped LiNixMnyCozO2 via (27)Al MAS NMR Spectroscopy.

    PubMed

    Dogan, Fulya; Vaughey, John T; Iddir, Hakim; Key, Baris

    2016-07-01

    Direct observations of local lattice aluminum environments have been a major challenge for aluminum-bearing Li ion battery materials, such as LiNi1-y-zCoyAlzO2 (NCA) and aluminum-doped LiNixMnyCozO2 (NMC). (27)Al magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy is the only structural probe currently available that can qualitatively and quantitatively characterize lattice and nonlattice (i.e., surface, coatings, segregation, secondary phase etc.) aluminum coordination and provide information that helps discern its effect in the lattice. In the present study, we use NMR to gain new insights into transition metal (TM)-O-Al coordination and evolution of lattice aluminum sites upon cycling. With the aid of first-principles DFT calculations, we show direct evidence of lattice Al sites, nonpreferential Ni/Co-O-Al ordering in NCA, and the lack of bulk lattice aluminum in aluminum-"doped" NMC. Aluminum coordination of the paramagnetic (lattice) and diamagnetic (nonlattice) nature is investigated for Al-doped NMC and NCA. For the latter, the evolution of the lattice site(s) upon cycling is also studied. A clear reordering of lattice aluminum environments due to nickel migration is observed in NCA upon extended cycling. PMID:27299505

  5. Synthesis, structure, and transport properties of type-I derived clathrate Ge(46-x)P(x)Se(8-y) (x = 15.4(1); y = 0-2.65) with diverse host-guest bonding.

    PubMed

    Kirsanova, Maria A; Mori, Takao; Maruyama, Satofumi; Matveeva, Maria; Batuk, Dmitry; Abakumov, Artem M; Gerasimenko, Andrei V; Olenev, Andrei V; Grin, Yuri; Shevelkov, Andrei V

    2013-01-18

    A first clathrate compound with selenium guest atoms, [Ge(46-x)P(x)]Se(8-y)□(y) (x = 15.4(1); y = 0-2.65; □ denotes a vacancy), was synthesized as a single-phase and structurally characterized. It crystallizes in the space group Fm3 with the unit cell parameter a varying from 20.310(2) to 20.406(2) Å and corresponding to a 2 × 2 × 2 supercell of a usual clathrate-I structure. The superstructure is formed due to the symmetrical arrangement of the three-bonded framework atoms appearing as a result of the framework transformation of the parent clathrate-I structure. Selenium guest atoms occupy two types of polyhedral cages inside the positively charged framework; all selenium atoms in the larger cages form a single covalent bond with the framework atoms, relating the title compounds to a scanty family of semiclathrates. According to the measurements of electrical resistivity and Seebeck coefficient, [Ge(46-x)P(x)]Se(8-y)□(y) is an n-type semiconductor with E(g) = 0.41 eV for x = 15.4(1) and y = 0; it demonstrates the maximal thermoelectric power factor of 2.3 × 10(-5) W K(-2) m(-1) at 660 K. PMID:23276305

  6. Dependence of the mixed alkali effect on temperature and total alkali oxide content in y[xLi{sub 2}O.(1-x)Na{sub 2}O].(1-y)B{sub 2}O{sub 3} glasses

    SciTech Connect

    Gao Yong . E-mail: yonggao@uni-muenster.de

    2005-11-15

    The complex conductivity spectra of mixed alkali borate glasses of compositions y [xLi{sub 2}O.(1-x)Na{sub 2}O].(1-y)B{sub 2}O{sub 3} (with x=0.0, 0.2, 0.4, 0.6, 0.8, 1.0; y=0.1, 0.2, 0.3) in a frequency range between 10{sup -2}Hz and 3MHz and at temperatures ranging from 298 to 573K have been studied. For each glass composition the conductivities show a transition from the dc values into a dispersive regime where the conductivity is found to increase continuously with frequency, tending towards a linear frequency dependence at sufficiently low temperatures. Mixed alkali effects (MAEs) in the dc conductivity and activation energy are identified and discussed. It has been for the first time found that the strength of the MAE in the logarithm of the dc conductivity linearly increases with the total alkali oxide content, y, and the reciprocal temperature, 1/T.

  7. Competing effects of Mn and Y doping on the low-energy excitations and phase diagram of La1 -yYyFe1 -xMnxAsO0.89F0.11 iron-based superconductors

    NASA Astrophysics Data System (ADS)

    Moroni, M.; Sanna, S.; Lamura, G.; Shiroka, T.; De Renzi, R.; Kappenberger, R.; Afrassa, M. A.; Wurmehl, S.; Wolter, A. U. B.; Büchner, B.; Carretta, P.

    2016-08-01

    Muon spin rotation (μ SR ) and 19F nuclear magnetic resonance (NMR) measurements were performed to investigate the effect of Mn for Fe substitutions in La1 -yYyFe1 -xMnxAsO0.89F0.11 superconductors. While for y =0 a very low critical concentration of Mn (x =0.2 % ) is needed to quench superconductivity, as y increases the negative chemical pressure introduced by Y for La substitution stabilizes superconductivity and for y =20 % it is suppressed at Mn contents an order of magnitude larger. A magnetic phase arises once superconductivity is suppressed both for y =0 and for y =20 % . Low-energy spin fluctuations give rise to a peak in 19F NMR 1 /T1 with an onset well above the superconducting transition temperature and whose magnitude increases with x . Also the static magnetic correlations probed by 19F NMR linewidth measurements show a marked increase with Mn content. The disruption of superconductivity and the onset of the magnetic ground state are discussed in the light of the proximity of LaFeAsO0.89F0.11 to a quantum critical point.

  8. Growth of Ga0.46In0.54NyAs1-y Single Quantum Wells on InP(100) Substrate by Metalorganic Chemical Vapor Deposition

    NASA Astrophysics Data System (ADS)

    Ubukata, Akinori; Dong, Jie; Matsumoto, Koh; Ishihara, Yoshio

    2000-10-01

    GaInNAs has been demonstrated as a 1 eV material that is lattice-matched to GaAs. Similarly, it is expected that for GaInNAs, which is lattice-matched to InP with an In content of over 50%, a band gap from 0.7 to 0.3 eV should be achievable if a few percent N could be incorporated. A Ga0.46In0.54NyAs1-y/InP single quantum well (SQW) structure grown at a relatively high growth temperature has been attempted. Low AsH3 partial pressure appeared to enhance N incorporation. A strong photoluminescence (PL) emission was observed without post-growth annealing at the growth temperature of 650 to 680°C. For our reactor, the PL properties of GaInNAs appeared to improve for the growth pressure of 120 Torr since a narrow PL linewidth as low as 32 meV was obtained at that pressure. In the low-temperature PL measurement, blue shift was observed.

  9. Facile synthesis and photoluminescence of near-infrared-emitting CdTe(x)Se(1-x) and CdTe(x)Se(1-x)/Cd(y)Zn(-1-y)S quantum dots.

    PubMed

    Zhang, Ruili; Wang, Jianrong; Yang, Ping

    2014-03-01

    High-quality colloidal photoluminescent (PL) CdTe(x)Se(1-x) quantum dots (QDs) with gradient distribution of components, consisting of Te-rich inner cores and Se-rich outer shells, were synthesized via a facile organic method using stearic acid as a capping agent. The transmission electron microscopy observation and X-ray diffraction analysis indicated that the CdTe(x)Se(1-x) QDs revealed a "dot" shaped morphology and exhibited a zinc-blende structure which located between those of bulk CdTe and CdSe (with the lattice parameters between those of bulk CdTe and CdSe). The ternary CdTe(x)Se(1-x) QDs were emitting in the red to near-infrared (NIR) range. In order to enhance the PL properties and reduce the sensitivity to oxidation of CdTe-based QDs, the CdTe(x)Se(1-x) QDs were coated with Cd(y)Zn(1-y)S multishells by using different growth kinetics of CdS and ZnS. The coated QDs exhibited a controlled red shift of PL compared with the initial CdTe(x)Se(1-x) cores and revealed much improved PL intensity. Because of thier tunable emission from red to NIR, these composite QDs open new possibilities in band gap engineering and in developing NIR fluorescent probes for biological imaging and detection. PMID:24745260

  10. Large superconducting double-gap, a pronounced pseudogap and evidence for proximity-induced topological superconductivity in the Bi2Te3/Fe1+yTe interfacial superconductor

    NASA Astrophysics Data System (ADS)

    Shen, J. Y.; He, M. Q.; He, Q. L.; Law, K. T.; Sou, I. K.; Lortz, R.; Petrovic, A. P.

    We investigate directional point-contact spectroscopy on a Bi2Te3/ Fe1+yTe heterostructure, fabricated via van der Waals epitaxy, which is interfacial superconducting with an onset TC at 12K and zero resistance below 8K. A large superconducting twin-gap structure is seen down to 0.27K, together with a zero bias conductance peak. The anisotropic smaller gap (Δ1) is around 5 meV at 0.27K and closes at 8K, while the other one (Δ2), as large as 12 meV, is isotropic and eventually evolves into a pseudogap closing at 40K. Both, the two-gap BTK and Dynes models can well reproduce our data, demonstrating Δ1 should be associated with the proximity-induced superconductivity in the topological Bi2Te3 layer, while Δ2 may be attributed to an intrinsically-doped FeTe thin film at the interface. This work was supported by grants from the Research Grants Council of the Hong Kong Special Administrative Region, China (603010, SEGHKUST03).

  11. Enhanced piezoelectricity in (1 -x)Bi1.05Fe1-yAyO3-xBaTiO3 lead-free ceramics: site engineering and wide phase boundary region.

    PubMed

    Zheng, Ting; Jiang, Zhenggen; Wu, Jiagang

    2016-07-28

    Site engineering has been employed to modulate the piezoelectric activity of high temperature (1 -x)Bi1.05Fe1-yScyO3-xBaTiO3 lead-free ceramics fabricated by a conventional solid-state method together with a quenching technique. The effects of x and y content on the phase structure, microstructure, and electrical properties have been investigated in detail. A wide rhombohedral (R) to pseudo-cubic (C) phase boundary was formed in the ceramics with x = 0.30 and 0 ≤y≤ 0.07, thus leading to enhanced piezoelectricity (d33 = 120-180 pC N(-1)), ferroelectricity (Pr = 19-22 μC cm(-2)) and a high Curie temperature (TC = 478-520 °C). In addition, the influence of different element substitutions for Fe(3+) on phase structure and electrical behavior was also investigated. Improved piezoelectricity (d33 = 160-180 pC N(-1)) and saturated P-E loops can be simultaneously achieved in the ceramics with A = Sc, Ga, and Al due to the R-C phase boundary. As a result, site engineering may be an efficient way to modulate the piezoelectricity of BiFeO3-BaTiO3 lead-free ceramics. PMID:27357104

  12. Structural, thermal and microstructural studies of the proton conductor BaCe0.7Zr0.1Y0.05Zn0.15O3 for IT-SOFCs

    NASA Astrophysics Data System (ADS)

    Hossain, S.; Radenahmad, N.; Zaini, J. H.; Begum, F.; Azad, A. K.

    2016-03-01

    The specimen of BaCe0.7Zr0.1Y0.05Zn0.15O3, a perovskite-type electrolyte, has been synthesized for application in an anode-supported protonic solid oxide fuel cell by the conventional solid state reaction in air at 1200°C for 12 hours. Structural and thermal characterization has been performed using room temperature X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA) and Differential Thermal Analysis (DTA). Rietveld analysis of the XRD data has been analyzed by FullProf program and confirmed the single phase of the sample with an orthorhombic crystal structure in the Pbnm space group. To understand the temperature dependent behaviour TG/DTA scan of the precursor was recorded. The TG/DTA scan was performed under constant flow of Argon which exhibits a gradual weight loss up to 900oC. The SEM image of the pellet surface of the sample shows that the sample sintered at 1200oC was dense and suitable to use as electrolyte in solid oxide fuel cells (SOFCs).

  13. Ni-induced local distortions in La1.85Sr0.15Cu1-yNiyO4 and their relevance to Tc suppression: An angular-resolved XAFS study

    NASA Astrophysics Data System (ADS)

    Haskel, Daniel; Stern, Edward A.; Polinger, Victor; Dogan, Fatih

    2001-09-01

    We present results from angular-resolved x-ray-absorption fine-structure (XAFS) measurements at the Ni, La, and Sr K edges of oriented powders of La1.85Sr0.15Cu1-yNiyO4, with y=0.01, 0.03, 0.06. A special magnetic alignment procedure allowed us to measure pure ĉ- and ab-oriented XAFS at the Ni K edge in identical fluorescence geometries. Both the x-ray-absorption near-edge structure and the XAFS unequivocally show that the NiO6 octahedra are contracted along the c axis by ~0.32 Å relative to CuO6 octahedra while the in-plane distances of NiO6 and CuO6 octahedra are the same within 0.01 Å. The NiO6 octahedral contraction drives the average ĉ axis contraction measured by diffraction with increasing content of Ni. The local ĉ axis shows strong spatial fluctuations, due to the different NiO6 and CuO6 octahedral configurations and the stronger bonding of a La3+ ion than a Sr2+ ion to the O(2) apical oxygens of such octahedra. We discuss the relevance of these findings to the mechanisms of loss of superconductivity at y~0.03 and hole localization above y~0.05 by Ni dopants.

  14. Characterization of Motor Control in Handwriting Difficulties in Children with or without Developmental Coordination Disorder

    ERIC Educational Resources Information Center

    Chang, Shao-Hsia; Yu, Nan-Ying

    2010-01-01

    Aim: The purpose of this study was to characterize handwriting deficits in children with developmental coordination disorder (DCD) using computerized movement analyses. Method: Seventy-two children (40 females, 32 males; mean age 7y, SD 7mo; range 6y 2mo to 7y 11mo) with handwriting deficits (33 with DCD, 39 without DCD); and 22 age- and…

  15. Investigating the reversibility of structural modifications of LixNiyMnzCo1-y-zO₂ cathode materials during initial charge/discharge, at multiple length scales

    SciTech Connect

    Hwang, Sooyeon; Bak, Seong -Min; Kim, Seung Min; Chung, Kyung Yoon; Chang, Wonyoung

    2015-08-11

    In this work, we investigate the structural modifications occurring at the bulk, subsurface, and surface scales of LixNiyMnzCo1-y-zO₂ (NMC; y, z = 0.8, 0.1 and 0.4, 0.3, respectively) cathode materials during the initial charge/discharge. Various analytical tools, such as X-ray diffraction, selected-area electron diffraction, electron energy-loss spectroscopy, and high-resolution electron microscopy, are used to examine the structural properties of the NMC cathode materials at the three different scales. Cut-off voltages of 4.3 and 4.8 V are applied during the electrochemical tests as the normal and extreme conditions, respectively. The high-Ni-content NMC cathode materials exhibit unusual behaviors, which is deviate from the general redox reactions during the charge or discharge. The transition metal (TM) ions in the high-Ni-content NMC cathode materials, which are mostly Ni ions, are reduced at 4.8 V, even though TMs are usually oxidized to maintain charge neutrality upon the removal of Li. It was found that any changes in the crystallographic and electronic structures are mostly reversible down to the sub-surface scale, despite the unexpected reduction of Ni ions. However, after the discharge, traces of the phase transitions remain at the edges of the NMC cathode materials at the scale of a few nanometers (i.e., surface scale). This study demonstrates that the structural modifications in NMC cathode materials are induced by charge as well as discharge at multiple length scales. These changes are nearly reversible after the first cycle, except at the edges of the samples, which should be avoided because these highly localized changes can initiate battery degradation.

  16. FTIR and Raman Study of the LixTiyMn1-yO2 (y = 0, 0.11) Cathodes in Methylpropyl Pyrrolidinium Bis(fluoro-sulfonyl)imide, LiTFSI Electrolyte

    SciTech Connect

    Hardwick, L.J.; Lucas, I.T.; Doeff, M.M.; Kostecki, R.; Saint, J.A.

    2009-02-02

    This work demonstrates the protective effect of partial titanium substitution in Li{sub x}Ti{sub 0.11}Mn{sub 0.89}O{sub 2} against surface decomposition in room-temperature ionic liquid (RTILs) cells. Raman microscopy and reflectance Fourier transform IR (FTIR) spectroscopy were used to analyze electrodes recovered from cycled Li/Li{sub x}Ti{sub y}Mn{sub 1-y}O{sub 2} (y=0, 0.11) cells containing the 0.5 mol/kg LiTFSI in P{sub 13}FSI RTIL electrolyte. [TFSI=bis(trifluoromethanesulfonyl)imide.] Raman and FTIR spectra of cycled Li{sub x}MnO{sub 2} cathodes showed many distinct bands that can be attributed to both the electrolyte and electrode decomposition products. The thickness of the amorphous porous layer on the Li{sub x}MnO{sub 2} cathode increased during cycling. The surface degradation of Li{sub x}MnO{sub 2} and precipitation of electrolyte decomposition products contributed to the film growth. Improved cycling behavior was observed in cells containing Li{sub x}Ti{sub 0.11}Mn{sub 0.89}O{sub 2}, yet Raman spectroscopy also showed possible surface degradation. The FTIR spectra of cycled Li{sub x}MnO{sub 2} and Li{sub x}Ti{sub 0.11}Mn{sub 0.89}O{sub 2} cathodes displayed bands characteristic for LiSO{sub 3}CF{sub 3} and Li{sub 2}NSO{sub 2}CF{sub 3}, which originate from the reaction of the TFSI anion with traces of water present in the cell.

  17. Tuning of magnetoelectric coupling in (1-y)Bi0.8Dy0.2FeO3-yNi0.5Zn0.5Fe2O4 multiferroic composites

    NASA Astrophysics Data System (ADS)

    Mazumdar, S. C.; Khan, M. N. I.; Islam, Md. Fakhrul; Hossain, A. K. M. Akther

    2016-03-01

    Magnetoelectric composites (1-y)Bi0.8Dy0.2FeO3 (BDFO)-yNi0.5Zn0.5Fe2O4 (NZFO) with y=0.0, 0.1, 0.2, 0.3, 0.4, 0.5 and 1.0 are synthesized by conventional solid state reaction route. The X-ray diffraction analysis confirms the coexistence of orthorhombic perovskite BDFO and spinel NZFO phases with no third phase. Microstructural and surface morphology are studied by Field Emission Scanning Electron Microscopy. Quantitative elemental analysis of the samples is carried out by Energy Dispersive X-ray Spectroscopy. The real part of the initial permeability increases and relative quality peak broadens with the ferrite content in the composites. Dielectric constant, loss tangent, relative quality factor and ac conductivity are measured as a function of frequency at room temperature. The dielectric constant shows usual dielectric dispersion at lower frequencies due to Maxwell-Wagner type interfacial polarization. The complex impedance spectroscopy is used to distinguish between the grain and grain boundary contribution to the total resistance. The modulus study reveals the ease of polaron hopping and negligibly small contribution of electrode effect. The magnetic hysteresis has been studied to know the response of NZFO phase to the applied magnetic field in the composite. The saturation and remanent magnetization are found to increase with increase in NZFO in the composite. The magnetoelectric voltage coefficient, αME is measured as a function of applied dc magnetic field. The tuning of ferrite percentage and dc magnetic field results in highest αME (~66 mV/cm Oe) for the composite with 40% NZFO at 4.7 kOe which is attributed to the enhanced mechanical coupling between the two phases. The incorporation of BDFO and NZFO enhances the multiferroic properties in the present composite which are quite promising from application point of view.

  18. Determination of structural, mechanical and corrosion properties of Nb2O5 and (NbyCu 1-y)Ox thin films deposited on Ti6Al4V alloy substrates for dental implant applications.

    PubMed

    Mazur, M; Kalisz, M; Wojcieszak, D; Grobelny, M; Mazur, P; Kaczmarek, D; Domaradzki, J

    2015-02-01

    In this paper comparative studies on the structural, mechanical and corrosion properties of Nb2O5/Ti and (NbyCu1-y)Ox/Ti alloy systems have been investigated. Pure layers of niobia and niobia with a copper addition were deposited on a Ti6Al4V titanium alloy surface using the magnetron sputtering method. The physicochemical properties of the prepared thin films were examined with the aid of XRD, XPS SEM and AFM measurements. The mechanical properties (i.e., nanohardness, Young's modulus and abrasion resistance) were performed using nanoindentation and a steel wool test. The corrosion properties of the coatings were determined by analysis of the voltammetric curves. The deposited coatings were crack free, exhibited good adherence to the substrate, no discontinuity of the thin film was observed and the surface morphology was homogeneous. The hardness of pure niobium pentoxide was ca. 8.64GPa. The obtained results showed that the addition of copper into pure niobia resulted in the preparation of a layer with a lower hardness of ca. 7.79 GPa (for niobia with 17 at.% Cu) and 7.75 GPa (for niobia with 25 at.% Cu). The corrosion properties of the tested thin films deposited on the surface of titanium alloy depended on the composition of the thin layer. The addition of copper (i.e. a noble metal) to Nb2O5 film increased the corrosion resistance followed by a significant decrease in the value of corrosion currents and, in case of the highest Cu content, the shift of corrosion potential towards the noble direction. The best corrosion properties were obtained from a sample of Ti6Al4V coated with (Nb0.75Cu0.25)Ox thin film. It seems that the tested materials could be used in the future as protection coatings for Ti alloys in biomedical applications such as implants. PMID:25492191

  19. Magnetoelectric coupling in lead-free piezoelectric Lix(K0.5Na0.5)1 - xNb1 - yTayO3 and magnetostrictive CoFe2O4 laminated composites

    NASA Astrophysics Data System (ADS)

    Fu, Jiyong; Santa Rosa, Washington; M'Peko, Jean Claude; Algueró, Miguel; Venet, Michel

    2016-04-01

    To replace lead zirconium titanate in magnetoelectric (ME) composites owing to concerns regarding its toxicity, we investigate the ME coupling in bilayer composites comprising lead-free Lix(K0.5Na0.5)1 - xNb1 - yTayO3 (LKNNT) (piezoelectric) and CoFe2O4 (magnetostrictive) phases. We prepare the LKNNT ceramics and measure its piezoelectric coefficient d31, a crucial ingredient determining ME couplings, for several Li (x = 0.03 , 0.035 , 0.04) and Ta (y = 0.15 , 0.2 , 0.25) concentrations, and find that the highest d31 occurs at y = 0.2 for all the values of x studied here. We then evaluate both the transverse (αE,31) and the longitudinal (αE,33) low-frequency ME coupling coefficients of our composites, for each the above composition of (x , y). At x = 0.03, we find the usual scenario of αE,31 and αE,33, i.e., the strongest ME coupling occurs when d31 is maximal, namely at y = 0.2. On the other hand, interestingly, we also obtain the strongest ME coupling when the LKNNT layer has a relatively weaker d31, e.g., at y = 0.25 for x = 0.035 and y = 0.15 for x = 0.04, following from the interplay of d31 and other ingredients (e.g., dielectric constant). Our calculated ME couplings, with αE,31 in magnitude around twice of αE,33, are comparable to those in lead-based composites. The effect of the volume fraction and interface parameter on the ME coupling is also discussed.

  20. Using real-time electron microscopy to explore the effects of transition-metal composition on the local thermal stability in charged LixNiyMnzCo1-y-zO2 cathode materials

    DOE PAGESBeta

    Hwang, Sooyeon; Kim, Seung Min; Bak, Seong -Min; Kim, Se Young; Cho, Byung -Won; Chung, Kyung Yoon; Lee, Jeong Yong; Stach, Eric A.; Chang, Wonyoung

    2015-05-08

    In this study, we use in-situ transmission electron microcopy (TEM) to investigate the thermal decomposition that occurs at the surface of charged LixNiyMnzCo1-y-zO2 (NMC) cathode materials of different composition (with y, z=0.8, 0.1 and 0.6, 0.2 and 0.4, 0.3), after they have been charged to their practical upper limit voltage (4.3V). By heating these materials inside the TEM, we are able to directly characterize near surface changes in both their electronic structure (using electron energy loss spectroscopy) and crystal structure and morphology (using electron diffraction and bright-field imaging). The most Ni-rich material (y, z = 0.8, 0.1) is found tomore » be thermally unstable at significantly lower temperatures than the other compositions – this is manifested by changes in both the electronic structure and the onset of phase transitions at temperatures as low as 100°C. Electron energy loss spectroscopy indicates that the thermally induced reduction of Ni ions drives these changes, and that this is exacerbated by the presence of an additional redox reaction that occurs at 4.2V in the y, z = 0.8, 0.1 material. Exploration of individual particles shows that there are substantial variations in the onset temperatures and overall extent of these changes. Of the compositions studied, the composition of y, z = 0.6, 0.2 has the optimal combination of high energy density and reasonable thermal stability. The observations herein demonstrate that real time electron microscopy provide direct insight into the changes that occur in cathode materials with temperature, allowing optimization of different alloy concentrations to maximize overall performance.« less