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  1. The Department of Obstetrics and Gynecology at Yale: the first one hundred fifty years, from Nathan Smith to Lee Buxton.

    PubMed Central

    Kohorn, E. I.

    1993-01-01

    The persons who directed the academic teaching of women's health at Yale Medical School are presented by biographical sketches recounting their achievements and some of the difficulties they encountered. Three who provided particular catalysis were Nathan Smith, Herbert Thoms, and Lee Buxton. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 PMID:8303913

  2. A proposal for a standardized system of reporting human lymph node morphology in relation to immunological function

    PubMed Central

    Cottier, H.; Turk, J.; Sobin, L.

    1972-01-01

    This Memorandum proposes a standardized system of reporting the histology of human lymph nodes based on commonly used simple staining techniques. The purpose is to provide a uniform, internationally acceptable system by which the histological structure of lymph nodes can be correlated with other parameters of immunological status. The proposed protocols are intended to provide information that is not available in conventional written reports, that use such terms as “hyperplasia” or “nonspecific lymphadenitis”. ImagesFigure 22Figure 13Figure 5Figure 4Figure 3Figure 14Figure 15Figure 9Figure 21Figure 8Figure 12Figure 17Figure 16Figure 2Figure 7Figure 6Figure 20Figure 19Figure 11Figure 10Figure 18 PMID:4539822

  3. Early chiropractic education in Oregon

    PubMed Central

    Keating, Joseph C

    2002-01-01

    Chiropractic education in the northwestern United States has its origins in the Marsh School & Cure in 1904. Most of the early schools were located in Portland, Oregon, including the D.D. Palmer College of Chiropractic (1908-1910), and several of these had merged by 1912 or 1913 to form the Pacific Chiropractic College, forerunner of today's Western States College. The latter was organized as a non-profit institution during the Great Depression, and struggled not only to survive but to create a higher standard. The early broad-scope of chiropractic training in the state probably encouraged the liberal scope of practice enjoyed in Oregon to this day. ImagesFigure 2Figure 3Figure 4Figure 6Figure 7Figure 8Figure 9Figure 11Figure 12Figure 13Figure 14Figure 15Figure 16Figure 18Figure 19Figure 20Figure 21Figure 22Figure 24

  4. Pulmonary mineral dust. A study of ninety patients by electron microscopy, electron microanalysis, and electron microdiffraction.

    PubMed Central

    Berry, J. P.; Henoc, P.; Galle, P.; Pariente, R.

    1976-01-01

    The results of a study of 90 patients are presented. Intrapulmonary mineral deposits were characterized by electron diffraction and electron probe microanalysis. Using this method, pneumoconioses may be distinguidhed from other pneumopathies. In cases of pneumoconiosis, there exists a specific relationship between the etiology of the dust exposure and the crystallographic characteristics of the intrapulmonary deposits. The nature of the deposits may be indicative of a specific type of pneumoconiosis. This method is particularly useful in differentiating between asbestos bodies and ferruginous bodies. The value of the method in general and its importance in the study of pneumoconiosis are discussed. Images Figure 4 Figure 13 Figure 5 Figure 14 Figure 6 Figure 15 Figure 7 Figure 16 Figure 8 Figure 17 Figure 1 Figure 9 Figure 10 Figure 2 Figure 11 Figure 3 Figure 12 PMID:937507

  5. Experimental lead nitrate poisoning: microscopic and ultrastructural study of the gills of tench (Tinca tinca, L.).

    PubMed Central

    Roncero, V; Vincente, J A; Redondo, E; Gãzquez, A; Duran, E

    1990-01-01

    A microscopic, ultrastructural, and morphometric study was made of the gills of tench (Tinca tinca, L.) subjected to acute experimental lead nitrate poisoning. Twenty-one adult tench were subjected to poisoning and a further 22 were used as controls. Lesions were characterized by the appearance of edema and epithelial hyperplasia and necrosis, both in cells forming part of the filtration barrier and in those in the interlamellar space. These processes developed in the course of the experiment, leading to the death of tench after 12 to 15 days of exposure to 75 ppm lead nitrate, at which point the concentrations of lead in the gills had reached their maximum. Images FIGURE 1. FIGURE 2. FIGURE 5. FIGURE 6. FIGURE 7. FIGURE 8. FIGURE 9. FIGURE 10. FIGURE 11. FIGURE 12. FIGURE 13. FIGURE 14. FIGURE 15. FIGURE 16. FIGURE 17. FIGURE 18. FIGURE 19. PMID:2088740

  6. Embryonic rationale for the primary correction of classical congenital clefts of the lip and palate.

    PubMed Central

    Millard, D. R.

    1994-01-01

    Primary correction of congenital clefts of the lip and palate should be designed to carry the interrupted embryonic process to normal completion. This is best accomplished by maxillary alignment with presurgical orthodontics, stabilisation of the maxillary alignment, obliteration of the alveolar cleft and construction of the nasal floor with periosteoplasty. This allows early construction of the lip by rotation and advancement and correction of the nose with columella lengthening, alar cartilage positioning and alar base cinching. This can be accomplished before school age. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 PMID:8017808

  7. Periocular xanthogranulomas associated with severe adult-onset asthma.

    PubMed Central

    Jakobiec, F A; Mills, M D; Hidayat, A A; Dallow, R L; Townsend, D J; Brinker, E A; Charles, N C

    1993-01-01

    This article describes six patients who presented, usually bilaterally, with yellow-orange, elevated, indurated, and nonulcerated xanthomatous eyelid lesions, typically extending into the anterior orbital fat, and sometimes involving the extraocular muscles and the lacrimal gland. Because the eyelids remained intact and because the process did not reach the deep orbital and perioptic connective tissues, visual acuity was well preserved. There is cosmetic morbidity and occasionally motility restriction with advancing involvement of the extraocular muscles. All patients had variably severe adult-onset asthma that required treatment with systemic prednisone and inhalants. No evidence of Erdheim-Chester disease was found in any patient, but the appearance in one patient, after 25 years of follow-up, of a separate subcutaneous necrobiotic xanthogranulomatous lesion in the mandibular region with an associated paraproteinemia, suggests that at least some of our cases might be a mild form of necrobiotic xanthogranuloma. For this reason, we would suggest repeated periodic serum protein immunoelectrophoretic studies as well as evaluation for lymphoma. Therapy probably should consist of low doses of periorbital radiotherapy coupled with high doses of corticosteroids. Should this not be successful, then systemic administration of corticosteroids with chemotherapeutic agents might be efficacious, as in necrobiotic xanthogranuloma. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 PMID:8140711

  8. A Workstation for Interactive Display and Quantitative Analysis of 3-D and 4-D Biomedical Images

    PubMed Central

    Robb, R.A.; Heffeman, P.B.; Camp, J.J.; Hanson, D.P.

    1986-01-01

    The capability to extract objective and quantitatively accurate information from 3-D radiographic biomedical images has not kept pace with the capabilities to produce the images themselves. This is rather an ironic paradox, since on the one hand the new 3-D and 4-D imaging capabilities promise significant potential for providing greater specificity and sensitivity (i.e., precise objective discrimination and accurate quantitative measurement of body tissue characteristics and function) in clinical diagnostic and basic investigative imaging procedures than ever possible before, but on the other hand, the momentous advances in computer and associated electronic imaging technology which have made these 3-D imaging capabilities possible have not been concomitantly developed for full exploitation of these capabilities. Therefore, we have developed a powerful new microcomputer-based system which permits detailed investigations and evaluation of 3-D and 4-D (dynamic 3-D) biomedical images. The system comprises a special workstation to which all the information in a large 3-D image data base is accessible for rapid display, manipulation, and measurement. The system provides important capabilities for simultaneously representing and analyzing both structural and functional data and their relationships in various organs of the body. This paper provides a detailed description of this system, as well as some of the rationale, background, theoretical concepts, and practical considerations related to system implementation. ImagesFigure 5Figure 7Figure 8Figure 9Figure 10Figure 11Figure 12Figure 13Figure 14Figure 15Figure 16

  9. Autopsy pathology in the acquired immune deficiency syndrome.

    PubMed Central

    Reichert, C. M.; O'Leary, T. J.; Levens, D. L.; Simrell, C. R.; Macher, A. M.

    1983-01-01

    The acquired immune deficiency syndrome (AIDS) is a devastating new illness which appears to be sexually and parenterally transmissible. AIDS was first described in the male homosexual community; however, the disease has more recently been described among intravenous drug abusers, Haitians, hemophiliacs, and others. The etiologic agent is unknown. AIDS may represent an infection by a previously undescribed organism, a mutant of a known microorganism, or a multifactorial combination of environmental, immunologic, and genetic factors. As a consequence of the disease's seemingly irreversible ablation of the cell-mediated immune system, AIDS victims succumb to a variety of infections and/or unusual neoplasms. In its fully developed form, mortality approaches 100%. At autopsy the gross and microscopic pathology of the syndrome can be divided into three general categories: 1) morphologic manifestations of profound lymphoid depletion; 2) infections, usually with mixed opportunistic pathogens; and 3) unusual neoplasms, most frequently Kaposi's sarcoma or high-grade lymphomas. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 21 PMID:6311021

  10. Rehabilitation After Anterior Cruciate Ligament Reconstruction in the Female Athlete

    PubMed Central

    Wilk, Kevin E.; Arrigo, Christopher; Andrews, James R.; Clancy, William G.

    1999-01-01

    Objective: To discuss the rehabilitation program after anterior cruciate ligament (ACL) reconstruction in the female athlete. In addition, we will discuss 8 unique characteristics identified in the female athlete and specific training drills to address and correct the potentially deleterious effects of these unique characteristics. Background: The female athlete appears to be more susceptible to noncontact ACL injuries than the male athlete. There seem to be many differences between the female and male athlete that may contribute to the increased injury rate in the female athlete. These variations include anatomical and neuromuscular considerations and differences. Description: Based on the unique characteristics of the female athlete and the anatomical and neuromuscular dissimilarities, a specially designed rehabilitation program has been established for the female athlete after ACL surgery. Clinical Advantages: The rehabilitation drills discussed in this article challenge the neuromuscular system through proprioception, kinesthesia, dynamic joint stability, neuromuscular control, and perturbation training activities. Improving the female athlete's neuromuscular system will, we believe, expedite the injured athlete's recovery after ACL injury or surgery. Although the concepts discussed are part of a postoperative rehabilitation program after ACL surgery, these concepts may also be implemented as a preventive program to assist in reducing the incidence of ACL injuries in the female athlete. ImagesFigure 1.Figure 2.Figure 4.Figure 5.Figure 6.Figure 7.Figure 8.Figure 9.Figure 10.Figure 11.Figure 12.Figure 13.Figure 14.Figure 15.Figure 16.Figure 17.Figure 18.Figure 19.Figure 20.Figure 21.Figure 22.Figure 23. PMID:16558561

  11. Familial canine dermatomyositis. Initial characterization of the cutaneous and muscular lesions.

    PubMed Central

    Hargis, A. M.; Haupt, K. H.; Hegreberg, G. A.; Prieur, D. J.; Moore, M. P.

    1984-01-01

    Familial canine dermatomyositis is a recently identified disease of collie dogs that resembles human juvenile dermatomyositis. The lesions in the skin and muscles obtained by biopsy from two litters of dogs were characterized for the purpose of determining the similarity of the lesions to those of human dermatomyositis. The cutaneous lesions began between 7 and 11 weeks of age and were present on the face, lips, ears, and skin over bony prominences of the limbs, feet, sternum, and tip of the tail. Histologically the cutaneous lesions frequently consisted of vesicles, pustules, and ulcers on the lips, face, and ears. Neutrophils, lymphocytes, mast cells, and macrophages were present throughout the dermis. Neutrophils and lymphocytes were also present in and around vessels. Between 13 and 19 weeks of age generalized muscle atrophy was noted. The muscle lesions consisted of interstitial lymphocyte, plasma cell, macrophage, and neutrophil accumulation; myofiber degeneration, regeneration, and atrophy; and fibrosis. Perivascular neutrophils, lymphocytes, and plasma cells were also seen. Histologically, the lesions resembled those present in human juvenile dermatomyositis; and these observations, coupled with clinical, immunologic, and clinical pathologic observations presented elsewhere, suggest that familial canine dermatomyositis is an appropriate and potentially useful model for human juvenile dermatomyositis. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 PMID:6465285

  12. A brief history of historical scholarship in chiropractic

    PubMed Central

    Keating, Joseph C

    2001-01-01

    This paper provides a cursory overview of attempts to discover, preserve and disseminate the history of the chiropractic profession, up to and including the organization of the Association for the History of Chiropractic (AHC). A surprisingly wide range of materials have been available for many decades, but sustained efforts at historical scholarship are more recent (past quarter century). The quality of these works has been uneven, but has improved with the emergence of chiropractic scholarly periodicals and interest from non-chiropractor investigators. Affiliates of the American-based AHC are located in Australia and Canada; organized historical scholarship in other regions of the world has yet to develop. Several substantial archival resources for historical investigations are available, and merit greater scrutiny and support within the profession. ImagesFigure 2Figure 3Figure 4Figure 5Figure 6Figure 7Figure 8Figure 9Figure 10Figure 11Figure 12Figure 13Figure 14Figure 15Figure 16Figure 17Figure 18Figure 19Figure 20Figure 21Figure 22Figure 23Figure 24Figure 25p136-ap136-bp136-cp136-dp136-e

  13. Characterization of the choroidal mast cell.

    PubMed Central

    Godfrey, W A

    1987-01-01

    The experimental studies performed on nonpigmented rat choroids and the review of the important literature covered in this thesis seem to justify the following statements: 1. Mast cells are present in the choroid in significant numbers. 2. Mast cell numbers vary considerably from one individual to another and from one location in the choroid to another. 3. The major concentration of mast cells in the uvea is in the posterior choroid. 4. The mast cells of the choroid have a preferential location along arterial vessels. 5. Choroidal mast cell population density apparently decreases with senescence. 6. Mast cell products are present in sufficient quantity to exert substantial effects on physiologic, immunologic, and inflammatory responses in the choroid. 7. Choroidal mast cell products are released with appropriate stimulation and share some properties with the connective-tissue mast cell. 8. Choroidal mast cell demonstrate enough differences to suggest that a local differentiation may be present and may represent a locally controlled modulating effect for choroidal physiologic, immunologic, and inflammatory reactions. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 PMID:3328921

  14. Immunocytochemical localization of peroxisomal enzymes in human liver biopsies.

    PubMed Central

    Litwin, J. A.; Völkl, A.; Müller-Höcker, J.; Hashimoto, T.; Fahimi, H. D.

    1987-01-01

    The immunocytochemical localization of catalase and three enzymes of the peroxisomal lipid beta-oxidation system--acyl-CoA oxidase, the bifunctional protein enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and 3-ketoacyl-CoA thiolase--in human liver biopsies was investigated by means of light and electron microscopy. The antisera raised against all four enzymes from rat liver cross-reacted with the corresponding proteins in homogenates of human liver as revealed by immunoblotting. For light-microscopic localization in glutaraldehyde-fixed Epon-embedded material, the removal of resin and controlled digestion with trypsin was necessary. At the ultrastructural level specific labeling for all four antigens was found by the protein A-gold technique in peroxisomes of liver parenchymal cells fixed with formaldehyde-low glutaraldehyde concentrations and embedded in Lowicryl K4M. In biopsies fixed with glutaraldehyde and embedded in Epon, treatment with metaperiodate or etching with sodium ethoxide improved the immunolabeling. After such treatment catalase showed the most intense labeling and acyl-CoA oxidase the weakest, the two other proteins exhibiting an intermediate immunoreaction. In material postfixed with osmium only catalase could be visualized in peroxisomes. The immunocytochemical investigation of peroxisomal proteins in human liver biopsies provides a simple and highly promising approach for further elucidation of the pathophysiology of peroxisomal disorders. Images Figures 2 and 3 Figure 4-7 Figures 9-12 Figure 1 Figure 8 Figure 13 Figure 14 Figure 15 Figure 16 PMID:2886050

  15. Ionescu-Shiley bovine pericardial bioprostheses. Histologic and ultrastructural studies.

    PubMed Central

    Hilbert, S. L.; Ferrans, V. J.; McAllister, H. A.; Cooley, D. A.

    1992-01-01

    Studies were done on the structural changes that develop in Ionescu-Shiley valves that are used as replacement heart valves for 4 to 8 years. These changes were compared with those found in similarly used porcine aortic valve (PAV) bioprostheses. A variety of morphologic differences were observed between bovine pericardial valve (BPV) and PAV bioprostheses after orthotopic implantation including: primary tissue failure associated with the use of an alignment suture, thickening of valve leaflet, leaflet tissue delamination, leaflet calcification, and dystrophic alterations of collagen. These findings indicate that valve design criteria directly influence the durability of pericardial valves. However, other factors unique to pericardial tissue also affect the durability and performance of BPVs. These factors include the inability of pericardial tissue to accommodate dynamic stresses; the extensive insudation of plasma proteins and lipids; and the inability to reduce leaflet calcification using agents that effectively mitigate calcification in PAV bioprostheses. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 PMID:1580331

  16. Pulmonary response and transmigration of inorganic fibers by inhalation exposure.

    PubMed Central

    Lee, K. P.; Barras, C. E.; Griffith, F. D.; Waritz, R. S.

    1981-01-01

    Rats, hamsters, and guinea pigs were exposed by inhalation to different concentrations of potassium octatitanate fibers. Following 3 months of exposure, the animals were sacrificed between the 15th and 24th month. The exposed animals showed dose-related dust deposition and pulmonary fibrosis mainly in the respiratory bronchiolar region. Most short fibers (less than 5 micrograms) were phagocytized by alveolar macrophages, but long fibers (greater than 10 micrograms) were phagocytized by foreign body giant cells. Dust-laden macrophages (dust cells) entered into the lumen of bronchial lymphatic or pulmonary blood vessels. Numerous dust cells were transported from the lung to the tracheobronchial and mediastinal lymph nodes where some dust cells penetrated into the blood or lymphatic circulation. Massive direct cell migration of the mediastinal adipose tissue from the lymph nodes occurred occasionally. Dust-laden giant cells were found only occasionally in the liver, and there was widespread migration of the fibers into other vital organs and tissues without any significant responses. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 PMID:7212016

  17. Immunohistochemical and ultrastructural analysis of medullary carcinoma of the thyroid in relation to hormone production.

    PubMed Central

    Kameya, T.; Shimosato, Y.; Adachi, I.; Abe, K.; Kasai, N.; Kimura, K.; Baba, K.

    1977-01-01

    Eighteen cases of medullary carcinoma of the thyroid were analyzed immunohistochemically for calcitonin- and ACTH-containing cells, and tumor cells in 8 cases were examined by an electron microscope and analyzed by manual and computer procedures with particular attention paid to the size and quality of secretory granules. Calcitonin- and ACTH-containing cells were found singly or in clusters in 14 and 11 tumors, respectively. In 4 cases, calcitonin-positive cell clusters and an increase in number of singly scattered C cells were seen apart from the main tumor, suggesting a multicentric nature of certain medullary carcinomas. Some ACTH-containing cells were apparently also positive for calcitonin. In a case of familial Sipple disease, follicular lining cells were replaced in areas with ACTH-containing cells. Three to five frequency distribution curves of the size of secretory granules were obtained in all of 6 cases analyzed, and at least two different types of granule matrix were identified. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 PMID:202164

  18. Light- and electron-microscopic histochemistry of Fabry's disease.

    PubMed Central

    Faraggiana, T.; Churg, J.; Grishman, E.; Strauss, L.; Prado, A.; Bishop, D. F.; Schuchman, E.; Desnick, R. J.

    1981-01-01

    A histochemical study was performed on light- and electron-microscopic level in a case of Fabry's disease. The patient underwent kidney transplantation for renal failure and died of heart failure 6 months later. Patient's tissues were studied at the light- and electron-microscopic levels with various embedding and staining techniques for lipids and carbohydrates. Two peroxidase-labeled lectins (from Ricinus communis and from Bandeiraea simplicifolia) known to have affinity for alpha- and beta-D-galactose, were strongly reactive with the storage material on frozen sections. The ultrahistochemical and extraction tests showed that the typical granules had a variable reactivity and morphologic characteristics in different cells, probably reflecting different composition. A small number of typical deposits were also observed in the transplanted kidney. This is the first reported case of recurrence of the storage disease in the allograft. Of interest was also the fact that the patient's blood inhibited normal alpha-galactosidase activity, suggesting a possible inhibitor-related mechanism in the pathogenesis of the recurrence. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 PMID:6786101

  19. Leukocytes in chemotactic-fragment-induced lung inflammation. Vascular emigration and alveolar surface migration.

    PubMed Central

    Shaw, J. O.

    1980-01-01

    Lung inflammation was induced in rabbits by intratracheal injections of chemotactic fragments obtained from zymosan-activated serum (CF-ZAS), and the route of vascular emigration and alveolar surface interaction of polymorphonuclear leukocytes (PMNs) and monocytes migrating into the lung was characterized by transmission (TEM) and scanning (SEM) electron-microscopic examination. Leukocytes migrated from capillaries and venules into the alveolar wall interstitium by adherence to the vascular endothelium and migration through the endothelial intracellular junction to attain a position between a reapposed endothelial cell junction and the vascular basement membrane. The cells then migrated into the interstitium through a narrow opening in the basement membrane. Leukocyte entrance into the alveolar space from the interstitium appeared to occur through small openings in the epithelial basement membrane at or near the Type I epithelial intercellular junction. Once in the alveolus, PMNs and macrophages demonstrated surface adherence and spreading along with evidence of migration, pseudopod extension, interalveolar pore transit, and retraction fiber formation. This study indicates the leukocyte influx into the alveolus in acute chemotactic-factor-induced inflammation is via a continuum of migrational activity, beginning at the pulmonary capillary endothelial surface and persisting on the alveolar epithelial surface. Images Figure 10 Figure 11 Figure 12 Figure 1 Figure 2 Figure 3 Figure 13 Figure 14 Figure 4 Figure 5 Figure 6 Figure 15 Figure 7 Figure 8 Figure 16 Figure 9 PMID:7435538

  20. The pathology of experimentally induced cecal amebiasis in gerbils (Meriones unguiculatus). Liver changes and amebic liver abscess formation.

    PubMed Central

    Chadee, K.; Meerovitch, E.

    1985-01-01

    The pathogenesis of experimentally induced cecal amebiasis in gerbils (Meriones unguiculatus) was studied from 5 to 60 days after inoculation. Ulcerative lesions were noted 10 to 60 days after inoculation. The sequential development of lesions was asynchronous and progressed from destruction of the interglandular epithelium and of glandular crypt elements to loss of mucosa and formation of granulomatous lesions in the submucosa involving the muscularis mucosae. Pathologic changes in the liver correlated with the formation of ulcerative cecal lesions. Subacute hepatic changes showed lymphocytic portal infiltrate, Kupffer cell hyperplasia, multinucleated giant cells, granuloma formation, and sinusoidal mononuclear and granulocytic infiltrates. Metastatic amebic liver abscesses occurred as early as 10 days after inoculation, and small abscesses were found in the portal areas of the right liver lobe. The sequential development and pathologic manifestation of the infection and the usefulness of the gerbil for the study of human intestinal amebiasis are discussed. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 PMID:4014436

  1. The pathogenesis of experimentally induced amebic liver abscess in the gerbil (Meriones unguiculatus).

    PubMed Central

    Chadee, K.; Meerovitch, E.

    1984-01-01

    Sequential development and pathology of experimentally induced amebic liver abscess in the gerbil (Meriones unguiculatus) were studied from 1 to 60 days after inoculation. Early lesions were characterized by an acute inflammatory response, which became granulomatous at 5 days. Early granulomas were discrete, with well-defined fibrohistiocytic walls. Trophozoite dissemination as a result of fibrolysis of granuloma wall was confined to the liver parenchyma. The granulomatous cellular infiltrate (less than 20 days) was characterized by granulocytes and histiocytes; older granulomas (greater than 30 days) were composed of lymphocytic infiltrate, plasma cells, and a few granulocytes, and were characterized by the absence of epithelioid histiocytes. The degree of pathologic change adjacent to liver granulomas followed the sequential development of the amebic liver abscess. Severe changes observed were portal canal lymphocytic infiltration, the presence of foreign body giant cells, periportal fibrosis, proliferation of bile duct epithelium, and hepatocyte anisonucleosis and ballooning degeneration. The pathogenesis of the infection and the usefulness of the gerbil model for the study of human amebiasis are discussed. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 PMID:6385727

  2. Age as a factor in the bacteriology and response to treatment of subperiosteal abscess of the orbit.

    PubMed Central

    Harris, G J

    1993-01-01

    The clinical course of SPA of the orbit is associated with the age of the patient. That association might be explained through a series of intermediate relationships: the clinical course correlates with the bacterial constituency, the bacterial constituency is related to physiologic derangement within the sinuses, the physiologic derangement may vary with the degree of obstruction of the sinus ostia, and the ostial caliber relative to the volume of the cavity that must be drained decreases with patient age into late adolescence. The controversy between pediatricians and surgeons over the appropriate indications for drainage might be resolved with the acknowledgement that each side is correct on the basis of the patient populations treated. It is hoped that recognition of the age-related variations in SPA will permit a more systematic approach to the management of this complex infectious disease. Images FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 FIGURE 25 FIGURE 26 FIGURE 27 PMID:8140703

  3. Chronic cutaneous graft-versus-host disease in man.

    PubMed Central

    Shulman, H. M.; Sale, G. E.; Lerner, K. G.; Barker, E. A.; Weiden, P. L.; Sullivan, K.; Gallucci, B.; Thomas, E. D.; Storb, R.

    1978-01-01

    This clinicopathologic study of patients with chronic graft-versus-host disease (GVHD) after allogeneic marrow transplantation emphasizes the most prominent feature of the syndrome, the cutaneous aspects, and describes the ophthalmic-oral sicca syndrome with sialoadenitis and the neurologic findings. Chronic cutaneous GVHD affected 19 of 92 recipients surviving 150 days or more. In 6 patients chronic GVHD presented as a continuation of acute GVHD; in 8 it occurred after the resolution of acute GVHD; and in 5 it arose without preceding acute GVHD, ie, de novo late onset. Two cutaneous types were distinguished. The generalized type affected 16 patients and ran a progressive course resulting in late complications of poikiloderma, diffuse dermal and subcutaneous fibrosis, and contractures. Microscopically, it resembled generalized morphea and lupus erythermatosus hypertrophicus et profundus. The local type affected 3 patients with a more variable picture of poikiloderma, dermal sclerosis, and contractures. Microscopically, it resembled lupus of erythematosus profundus and scleroderma. Guidelines for defining and subclassifying chronic cutaneous GVHD are proposed. Images Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 1 Figure 2 Figure 3 Figure 4 PMID:26221

  4. Specialized structure and metabolic activities of high endothelial venules in rat lymphatic tissues.

    PubMed Central

    Anderson, N D; Anderson, A O; Wyllie, R G

    1976-01-01

    Microscopic, histochemical and ultrastructural techniques were used to define characteristics of high endothelial venules (HEV) in rat lymphatic tissues. This endothelium contained acetyl esterase and acid hydrolase activities which were not altered by lymphocyte depletion. No immunoglobulins were detected on luminal surfaces of HEV by fluorescent antibody staining. Only minor structural differences were seen between HEV within lymph nodes and Peyer's patches. At both sites, high endothelial cells were linked together by macular junctional complexes and interlocking basal foot processes. Endothelial cell cytoplasm moulded about surfaces of lymphocytes migrating through the venular wall, and flocculant deposits of basement membrane formed over lymphocytes penetrating the basal lamina. The endothelium was ensheathed by three to five layers of overlapping reticular cell plates and connective tissue. Each plate was linked to the reticular meshwork of the node by collagen bundles and anchoring filaments which inserted into the plate's external limiting membrane. This permitted individual paltes to separate or approximate each other as tissue and intravascular pressure varied, and lymphocytes moved across the sheath by insinuating themselves into gaps between overlapping plates. This composite structure of the HEV wall appeared to facilitate lymphocyte entry into the node and minimized vascular leakge. Images Figures 11-13 Figures 1-4 Figure 5 Figure 6 Figure 7 Figure 8 Figures 9-10 Figures 14-15 Figure 16 Figures 17-20 Figure 22 Figure 23 Figure 24 PMID:1027726

  5. Cryo-transmission electron microscopy of a superstructure of fluid dioleoylphosphatidylcholine (DOPC) membranes.

    PubMed Central

    Klösgen, B; Helfrich, W

    1997-01-01

    Using cryo-transmission electron microscopy, we have obtained abundant and reproducible evidence for a superstructure of dioleoylphosphatidylcholine (DOPC) bilayers. Dispersions of vesicles were prepared by gentle shaking of a 2% suspension of DOPC in water followed in part by extrusion through a porous technical membrane. Sampling and cryofixation took place at various times within 3 weeks after the preparation. From the micrographs we infer that the small fraction of vesicles enclosing one another develop passages (connections) between the bilayers. In contrast, the superstructure is basically a feature of disconnected membranes. Among its modifications are isolated membrane bends or folds and a grainy membrane texture with a minimal grain spacing of 4-6 nm. In the extruded dispersions the passages and the superstructure seem to be formed mostly within the first day. The fraction of smooth and unilamellar vesicles is large at all times and in all dispersions. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 PMID:9414216

  6. Before Nugent took charge: early efforts to reform chiropractic education, 1919-1941

    PubMed Central

    Keating, Joseph C

    2003-01-01

    John J. Nugent, D.C. is remembered by many as either the “Abraham Flexner of Chiropractic” or the “anti-Christ of Chiropractic.” From 1941 until his forced retirement in 1959, the Irish-born Palmer graduate was one of the most important factors in the profession's educational reforms. Yet Nugent's work as the National Chiropractic Association's (NCA's) director of research was not the beginning of the campaign to upgrade chiropractic education. This paper looks at earlier influences and events which set the stage for Nugent's campaign. Among these were the introduction of licensure for chiropractors, the self-defeating actions of B.J. Palmer, the introduction of basic science legislation, the lethargy of the schools, and the struggle for control of education between the schools, on the one hand, and the NCA and the Council of State Chiropractic Examining Boards on the other ImagesFigure 1Figure 3Figure 4Figure 5Figure 6Figure 7Figure 9Figure 10Figure 11Figure 12Figure 13Figure 14Figure 15Figure 16Figure 17Figure 18Figure 19Figure 20Figure 21Figure 22Figure 23Figure 24Figure 25Figure 26Figure 28Figure 29Figure 30Figure 31Figure 32Figure 33Figure 34Figure 35Figure 36Figure 37Figure 38

  7. Ultrastructure of sarcoplasmic reticulum in atrial myocardium of patients with mitral valvular disease.

    PubMed Central

    Thiedermann, K. U.; Ferrans, V. J.

    1976-01-01

    Alterations observed in the sarcoplasmic reticulum of muscle cells in left and right atrial myocardium from 10 patients with mitral valvular disease consisted of: a) proliferation of rough-surfaced endoplasmic reticulum, which formed large cisterns in perinuclear areas of hypertrophied cells and was considered indicative of increased protein synthesis; b) proliferation of free sarcoplasmic reticulum, a change that occurred in degenerated cells and appeared to be related to loss of contractile elements; c) two types of aggregates of tubules of free SR--one type was associated wtih abnormal Z-band material and was found only in cells showing loss of myofibrils and proliferation of free SR, whereas the other was not associated with either of these changes and occurred in less severely altered cells; and d) proliferation and enlargement of cisterns of extended junctional sarcoplasmic reticulum, which formed two distinct types of complexes: the first of these consisted of large, convoluted (Type A) cisterns that were wide (550 to 650 A in thickness) and did not have a central dense lamina; the second was composed of stacks of concentric or parallel (Type B) cisterns that were narrower (220 to 300 A in thickness), had a central dense lamina, and were separated from one another by layers of glycogen granules. The formation of these complexes of cisterns was regarded as an extreme form of overdevelopment of extended junctional sarcoplasmic reticulum in atrial muscle cells. Images Figure 21 Figures 22-25 Figures 1-3 Figures 26-29 Figure 4 Figure 5 Figure 6 Figures 30 and 31 Figure 7 Figure 8 Figure 9 Figure 10 Figures 32-36 Figure 11 Figure 12 Figures 37-39 Figure 15 Figure 16 Figure 17 Figure 13 Figure 14 Figures 40 and 41 Figure 18 Figures 19 and 20 PMID:1275054

  8. Efficient Calculation of Earth Penetrating Projectile Trajectories

    DTIC Science & Technology

    2006-09-01

    seconds and stable trajectories are solved in less than three seconds. 15. NUMBER OF PAGES 119 14 . SUBJECT TERMS Ballistic, Penetration, Simulation...Bottom Half of Weapon from 2 Degree Angle of Attack ............... 14 Figure 9. Moment on Top Half of Weapon from a 2 Degree Angle of Attack... 14 Figure 10. Forces on Bottom Half of Weapon from 2 Degree Angle of Attack ...............15 Figure 11. Additional Areas of Stress Due to

  9. Adaptive, Tactical Mesh Networking: Control Base MANET Model

    DTIC Science & Technology

    2010-09-01

    pp. 316–320 Available: IEEE Xplore , http://ieeexplore.ieee.org [Accessed: June 9, 2010]. [5] N. Sidiropoulos, “Multiuser Transmit Beamforming...Mobile Mesh Segments of TNT Testbed .......... 11 Figure 5. Infrastructure and Ad Hoc Mode of IEEE 802.11................................ 13 Figure...6. The Power Spectral Density of OFDM................................................ 14 Figure 7. A Typical IEEE 802.16 Network

  10. A Geographic and Functional Network Flow Analysis Tool

    DTIC Science & Technology

    2014-06-01

    13 Figure 5. Quantum GIS with the ArcMaker plugin.........................................................14 Figure 6...System PPD-21 Presidential Policy Directive 21 QGIS Quantum GIS XML Extensible Markup Language xiv THIS PAGE INTENTIONALLY LEFT...heavily on Quantum GIS (QGIS 2012) to model our simulated networks. QGIS is a free, open source Geographic Information System software suite. We ran

  11. An Analysis of Serial Number Tracking Automatic Identification Technology as Used in Naval Aviation Programs

    DTIC Science & Technology

    2002-09-01

    13 1. Strengths ................................... 14 2. Weaknesses .................................. 14 E. SMART CARDS ...................................... 15...13 Figure 3. Magnetic Stripe .................................. 15 Figure 4. Smart Card with Magnetic Stripe and ICC .......... 18 Figure 5...2002) Figure 3. Magnetic Stripe E. SMART CARDS Integrated Circuit Cards or Smart Cards are devices the size and shape of a credit card that contain

  12. 100 Gbit Interconnects and Above: The Need for Speed

    DTIC Science & Technology

    2007-01-01

    ADM002197. 14 . ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT Same as Report (SAR) 18. NUMBER OF PAGES... 14 3.6 Protocols for the data center...interconnects .............. 14 Figure 7: Simplistic view of the current network (Core, Metro, Access, and Last Mile) ............. 15 Figure 8: Basics

  13. Framework for Estimating National Economic Development Benefits and Other Beneficial Effects of Flood Warning and Preparedness Systems

    DTIC Science & Technology

    1994-03-01

    11 Figure 5 - Shifting Linear Damage Curve ....... .................... 12 Figure 6 - Linear 3- D Damage Function...14 Figure 7 - Non-Linear 3- D Damage Function ....... .................. 15 Figure 8 - Damage Contour in Stage - Warning Space...Studies (P& G ) (Water Resources Council, 1983) and the National Economic Development Procedures Manual-Urban Flood Damage (Davis, et. al., 1988). It further

  14. Fire Extinguishing Performance of Firebane on JP-8 Jet Fuel Fires

    DTIC Science & Technology

    2012-04-17

    agent used, and effectiveness on the fires. Compressed air foam systems were used for the evaluations, the recommended agent delivery method for...the engine protocol pool fire ....................................... 14 Figure 6. Firebane 1115 foam blanket during engine nacelle test...15 Figure 7. 50-percent Firebane 1115 foam blanket during engine nacelle test .............................. 15

  15. Development of a Nonlinear 6-Degree of Freedom Miniature Rotary-Wing Unmanned Aerial Vehicle Software Model and PID Flight Path Controller Using MathWorks Simulink Simulation Environment

    DTIC Science & Technology

    2009-09-01

    MONITORING AGENCY NAME(S) AND ADDRESS(ES) N/A 10 . SPONSORING/MONITORING AGENCY REPORT NUMBER 11. SUPPLEMENTARY NOTES The views expressed in this...14 Figure 9. Channel Model Responses...............................................................................15 Figure 10 ... 10 Table 3. Sample of Full-Scale Aircraft Control Ranges (After [3

  16. Atmospheric Effects on Radio Frequency (RF) Wave Propagation in a Humid, Near-Surface Environment

    DTIC Science & Technology

    2010-03-01

    14 Figure 10. Transmit site M1 (foreground) and MNPS (background). Towers were identified as follows: M1 (NRL tower #1, Tx site), M2 (NRL... tower #2, Rx site), and MNPS (NPS tower , Tx site). ..............................................................15 Figure 11. Representative sample...34 Figure 23. Time-series sub-plot of ε1 to solar irradiance. .................................................35 Figure

  17. Experimental Studies of the Number 41 Primer and Ignition 5.56-mm Ammunition

    DTIC Science & Technology

    2006-09-01

    caliber primers are lead styphnate , barium nitrate, and antimony sulfide, Sb2S3. Lesser amounts of aluminum powder, tetracene, and...this particle, which apparently did not melt, consists primarily of Barium . ...........................................................14 Figure 17...15 Figure 21. Reference spectrum of barium nitrate (top) compared to a spectrum representative (**splat) of many residual particles from

  18. Cardiac disease induced by chronic adriamycin administration in dogs and an evaluation of vitamin E and selenium as cardioprotectants.

    PubMed Central

    Van Vleet, J. F.; Ferrans, V. J.; Weirich, W. E.

    1980-01-01

    Chronic adriamycin (ADR) intoxication was produced in three groups of beagle dogs by weekly intravenous injections (1 mg/kg body weight) for 20 weeks (cumulative dose 400 mg/sq m). Group A (6 dogs) received ADR only; Group B (6 dogs) were given ADR and weekly doses of vitamin E (17 mg/kg body weight) as alpha-tocopherol acetate; and Group C (6 dogs) received ADR and weekly doses of vitamin E as did Group B and selenium (0.06 mg/kg body weight as selenite). Each of the 18 dogs developed ADR-induced cardiomyopathy (CMY), and death occurred in 11 dogs during Weeks 17-20. Mortality was lowest in Group B (2 of 6), but no differences between groups were seen either in survival time of the dogs that died or in severity of CMY. Cardiomyopathy was more severe in dogs that died than in survivors. Congestive heart failure with transudation was present in 4 of 11 dogs that died. Cardiac histopathology was characterized by vacuolar degeneration of myocytes. Myocardial damage was most severe in the left ventricle and the ventricular septum, intermediate in the right ventricle and the left atrium, and least in the right atrium. Ultrastructural study showed that an early alteration in damaged myocytes was distention of sarcoplasmic reticulum to form sarcoplasmic vacuoles. Occasional damaged fibers had myofibrillar lysis and focal proliferation of sarcoplasmic reticulum. This study demonstrates that the dog offers a suitable model for studies of chronic ADR cardiotoxicity in man. The lack of cardioprotection from vitamin E and selenium supplementation fails to support the proposed role of lipoperoxidative damage in the development of chronic ADR-induced CMY. Images Figure 9 Figure 10 Figure 1 Figure 2 Figure 11 Figure 12 Figure 13 Figure 3 Figure 4 Figure 5 Figure 14 Figure 15 Figure 6 Figure 7 Figure 8 Figure 16 Figure 17 Figure 18 Figure 19 PMID:7361854

  19. The development of the trabecular meshwork and its abnormality in primary infantile glaucoma.

    PubMed Central

    Anderson, D R

    1981-01-01

    Tissue from ten eyes with infantile glaucoma and from 40 normal eyes of fetuses and infants without glaucoma were examined by light and electron microscopy. In normal development, the corneoscleral coat grows faster than the uveal tract during the last trimester, leading to a posterior migration of the ciliary body attachment from Schwalbe's line (5th month) to the scleral spur (9th month), and then to a location behind the scleral spur (postnatally). In infantile glaucoma, the insertion of the anterior ciliary body and iris overlaps the trabecular meshwork, similar to the late fetal position. The trabecular sheets are perforated, and there is no membrane over the surface of the trabecular meshwork. The trabecular beams are thicker than in normal infant eyes. There is both histologic and clinical evidence of traction on the iris root exerted by the thickened trabecular beams. These findings suggest that in congenital glaucoma the thickened beams had prevented the normal posterior migration of the ciliary body and iris root. This traction may compact the thickened trabecular beams, obstructing aqueous humor outflow. Release of the traction by an incision (goniotomy or trabeculotomy) of the thickened meshwork may relieve the obstruction. Of uncertain pathological significance is that there are no vacuoles in the endothelium of Schlemm's canal and there is a broad layer of collagen and amorphous material in the juxtacanalicular connective tissue. The ciliary processes are elongated inward, as if they were pulled by zonular traction (perhaps created by an enlarging diameter of the limbus with a fixed lens diameter). Images FIGURE 7 FIGURE 8 FIGURE 10 FIGURE 11 FIGURE 20 A FIGURE 20 B FIGURE 1 FIGURE 3 FIGURE 4 A FIGURE 4 B FIGURE 5 A FIGURE 5 B FIGURE 6 FIGURE 9 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 PMID:7342408

  20. Glomerular lesions induced in the rabbit by physicochemically altered homologous IgG.

    PubMed Central

    Cavalot, F.; Miyata, M.; Vladutiu, A.; Terranova, V.; Dubiski, S.; Burlingame, R.; Tan, E.; Brentjens, J.; Milgrom, F.; Andres, G.

    1992-01-01

    Immunization of rabbits with physicochemically altered homologous or even autologous IgG induces formation of antibodies combining with IgG of rabbit and of foreign species. Cardiac but not renal lesions were reported in such animals. This study examined the nephritogenic potential of the immune response to cationized or heat-aggregated homologous IgG of b9 or b4 allotype in rabbits of the b4 allotype. Rabbits injected with either b9 or b4 cationized IgG produced antibodies reactive with rabbit and human IgG and with histones; they also developed abnormal glomerular deposits of IgG b4 and C3 corresponding to alterations of the glomerular basement membranes (GBM). Rabbits injected with either b9 or b4 aggregated IgG developed antibodies reactive with rabbit and human IgG and abnormal glomerular deposits of IgG b4 and C3 in the GBM and in the mesangium with subendothelial and mesangial electron-dense deposits. Some rabbits in both groups had proliferative and exudative glomerulonephritis and proteinuria. The results showed that immunization of rabbits with physicochemically altered homologous IgG induces an immune response to rabbit and human IgG and to histones as well as glomerular deposits of autologous IgG and C3 and other glomerular lesions. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 21 Figure 22 Figure 23 Figure 24 Figure 25 Figure 26 Figure 27 Figure 28 Figure 29 Figure 30 PMID:1546743

  1. Transplant arteriosclerosis in a rat aortic model.

    PubMed Central

    Isik, F. F.; McDonald, T. O.; Ferguson, M.; Yamanaka, E.; Gordon, D.

    1992-01-01

    Transplant arteriosclerosis (TA) has emerged as an obstacle to the long-term survival of transplanted organs, especially cardiac transplants. The animal models that have been used to study TA have not been fully characterized with regard to features such as the time course of cell proliferation and the sequence of cell types arriving in the developing intimal lesion. We present a model of TA based on a transplanted segment of abdominal aorta that helps address these questions. Two strains of rats (PVG x DA) underwent orthotopic aortic transplantation without immunosuppression and were killed at 14, 20, 40, and 60 days after transplantation. The within-strain control group displayed minimal evidence of cellular rejection with minimal to absent intimal lesions. In contrast, the allograft group showed a linearly increasing intimal lesion, up through 60 days after transplantation. The mechanism of intimal thickening was by an increase in cell number at the earlier time points with the later deposition of extracellular matrix. The early intimal lesion consisted mostly of mononuclear inflammatory cells (45%) with gradually increasing presence of smooth muscle cells (SMC) in the intima between 20 and 60 days. Conversely, the media showed gradual infiltration by macrophage-type cells with virtual loss of all SMC from the media by 40 days. The proliferative index showed a peak of 6% and 8% at 20 days in both the intima and media, respectively, and was preceded by the presence of macrophages. In fact, most of the proliferating cells at the earlier time points were either monocytes/macrophages, or were immediately adjacent to monocyte-/macrophage-rich regions. This straight artery segment model of transplant arteriosclerosis provides an easily quantifiable system in which the effects of different interventions (e.g., immunosuppressive regimens) can be tested. Images Figure 2 Figure 3 Figure 6 Figure 7 Figure 8 Figure 9 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure

  2. The association of viruses with urveal melanoma.

    PubMed Central

    Albert, D M

    1979-01-01

    Electron microscopic examination of 57 ocular melanomas (54 human, two feline and one canine) revealed the presence of viral particles in six specimens. Herpesviruses particles were observed in one human specimen and were passed in human fibroblasts (WI-38), where they gave rise to intranuclear inclusions. A-type oncornavirus particles (oncogenic RNA virus) were observed in a second case, both in cells of tumor directly removed from an enucleated eye as well as in cells grown in tissue culture. In three human specimens and one feline specimen, togavirus particles were observed. Rubella is a member of this group, and the possibility that the presence of togavirus in these tumors is the result of latent ocular infection by rubella virus is raised. Herpes virus and RNA tumor viruses are widely considered as having a possible etiologic role for certain human cancers. The observation of togavirus is unexpected, as this virus has not been previously implicated in human or animal tumors. Injection of an RNA tumor virus (Gardner strain feline sarcoma virus) into the anterior chamber of newborn kittens resulted in the development of iris and ciliary body melanomas, many of which showed invasion and, in one instance, metastasis. This is the first animal model of a viral-induced uveal melanoma, and the histology and ultrastructure are described. These results emphasize the need for the continued investigation of the role of these viruses in uveal melanoma. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 PMID:545833

  3. Computational functions in biochemical reaction networks.

    PubMed Central

    Arkin, A; Ross, J

    1994-01-01

    In prior work we demonstrated the implementation of logic gates, sequential computers (universal Turing machines), and parallel computers by means of the kinetics of chemical reaction mechanisms. In the present article we develop this subject further by first investigating the computational properties of several enzymatic (single and multiple) reaction mechanisms: we show their steady states are analogous to either Boolean or fuzzy logic gates. Nearly perfect digital function is obtained only in the regime in which the enzymes are saturated with their substrates. With these enzymatic gates, we construct combinational chemical networks that execute a given truth-table. The dynamic range of a network's output is strongly affected by "input/output matching" conditions among the internal gate elements. We find a simple mechanism, similar to the interconversion of fructose-6-phosphate between its two bisphosphate forms (fructose-1,6-bisphosphate and fructose-2,6-bisphosphate), that functions analogously to an AND gate. When the simple model is supplanted with one in which the enzyme rate laws are derived from experimental data, the steady state of the mechanism functions as an asymmetric fuzzy aggregation operator with properties akin to a fuzzy AND gate. The qualitative behavior of the mechanism does not change when situated within a large model of glycolysis/gluconeogenesis and the TCA cycle. The mechanism, in this case, switches the pathway's mode from glycolysis to gluconeogenesis in response to chemical signals of low blood glucose (cAMP) and abundant fuel for the TCA cycle (acetyl coenzyme A). Images FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 7 FIGURE 10 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 PMID:7948674

  4. Ultrastructural alterations in allylamine cardiovascular toxicity. Late myocardial and vascular lesions.

    PubMed Central

    Boor, P. J.; Ferrans, V. J.

    1985-01-01

    The late myocardial and vascular ultrastructural changes in rat hearts following consumption of the cardiovascular toxin allylamine were studied. Rats were given 0.1% allylamine HCl in drinking water for 10-104 days. From 10 to 21 days, there was organization of acute myocardial necrosis by macrophages and scattered polymorphonuclear leukocytes with prominent interstitial-cell proliferation. Alterations at 21-104 days included extensive scarring with formation of dense mature collagen with scattered fibroblasts present, grossly evident left-ventricular aneurysm, and gross and microscopic changes similar to those observed in the secondary form of endocardial fibroelastosis. Areas of scar contained highly cellular foci of smooth-muscle cells, myofibroblasts, and abundant extracellular elastin. Cardiac myocytes frequently showed markedly disorganized myofilaments, bizarrely distorted mitochondria with condensed cristae, and other severe degenerative changes. Small vessels within and adjacent to scar showed proliferation of intimal smooth-muscle cells. Endothelial lesions or recent or organized thrombi were not seen. Focal endocardial metaplasia, consisting of both chondroid and osseous tissue, was found in areas of transmural scarring, or ventricular aneurysm. Chondrocytes had the overall nuclear and cellular morphology, abundant rough endoplasmic reticulum, and surrounding lacunae typical of mature fibrocartilage. In some areas, the collagen matrix was undergoing calcification with the typical cross-banded pattern of calcifying connective tissue. Osteocytes were located in a densely calcified bone matrix and displayed characteristic cellular extensions into surrounding canaliculi. These findings indicate a severe myocardial, small-vessel, and endocardial injury during the course of chronic allylamine intoxication. Images Figure 13 Figure 14 Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 15 Figure

  5. Information Security: Federal Guidance Needed to Address Control Issues With Implementing Cloud Computing

    DTIC Science & Technology

    2010-05-01

    Figure 2: Cloud Computing Deployment Models 13 Figure 3: NIST Essential Characteristics 14 Figure 4: NASA Nebula Container 37...Access Computing Environment (RACE) program, the National Aeronautics and Space Administration’s (NASA) Nebula program, and the Department of...computing programs: the DOD’s RACE program; NASA’s Nebula program; and Department of Transportation’s CARS program, including lessons learned related

  6. Detailed Analysis Case Studies of Trapped Plasmas at the Earth’s Magnetic Equator

    DTIC Science & Technology

    1993-06-01

    5 Figure 2. Plasma Density L Dependance ...... ......... 7 Figure 3. Plasmapause Magnetic Activity Dependance . . 8 Figure 4. Plasma Density L... Dependance - Normalized . . 10 Figure 5. The Dusk Bulge . . . .............. 13 Figure 6. Magnetosphere’s Electric and Magnetic Fields 14 Figure 7...1970). 6 -. ~ .ZJ.:AUGUST 12,1968 . -. ----- OUTBOUND PASS - 2 3 4 5 ___ ... 7....9 L Figure 2. Plasma Density L Dependance 7 0D3 #n /2 OUT JND tN

  7. Characterization of Seismic Noise at Selected Non-Urban Sites

    DTIC Science & Technology

    2010-03-01

    Hz center frequency for vertical, east-west and north-south components of wind farm ground motion during the 50-min periods 0000 - 0050 (turbines...13 Figure 6. Hourly power PDFs at 4-Hz center frequency for vertical ground motion for the period 0400 – 1200 GMT...15 Figure 7. Wind speed data recorded at the Enfield site. Data dropouts occurred during the 10-min periods

  8. Modeling and Measurement of Electromagnetic Fields Near LORAN-C and OMEGA Stations

    DTIC Science & Technology

    1987-06-15

    NEC model with top - 13 radial guys Figure 4. LaMoure OMEGA NEC model showing wire numbers 14 Figure 5. LaMoure OMEGA modeling results showing 15...Figure 13. Nantucket LORAN modeling results for 26 electric fields Figure 14 . Nantucket LORAN modeling results for 27 magnetic fields Figure 15. Dana...antennas 14 . Electric and magnetic field strength meter 61 requirements 15. Electric field meter calibration results 66 (low range) 16. Electric field

  9. An Inverse Model of Double Diffusive Convection in the Beaufort Sea

    DTIC Science & Technology

    2009-12-01

    Master’s Thesis 4. TITLE AND SUBTITLE An Inverse Model of Double Diffusive Convection in the Beaufort Sea 6. AUTHOR(S) Jeremiah E. Chaplin 5 ...convection and mixing within the homogeneous layers............................... 5 Figure 4. Ice tethered profiler system....................14...Figure 5 . Location of ITP 1-6.............................15 Figure 6. Temperature – Salinity plot for ITPs 1-6........18 Figure 7. Histogram of data

  10. Countering Overseas Threats: DOD and State Need to Address Gaps in Monitoring of Security Equipment Transferred to Lebanon

    DTIC Science & Technology

    2014-02-01

    2013 5 Figure 3: Photographs of Lebanese Armed Forces Equipment Prepared for End-Use Monitoring 14 Figure 4: U.S. Officials Conducting an Inventory...of U.S.-Provided Equipment at a Lebanese Armed Forces Facility 15 Figure 5: Photographs of U.S. Equipment Provided to Lebanon’s Internal Security...Assistance to Lebanon Figure 3: Photographs of Lebanese Armed Forces Equipment Prepared for End-Use Monitoring During our visit to Beirut in July

  11. The Aerodynamics of a Maneuvering UCAV 1303 Aircraft Model and its Control through Leading Edge Curvature Change

    DTIC Science & Technology

    2012-09-01

    14 Figure 9. UCAV 1303 Model with Dimensions (Inches). From [1]. ..............................15 Figure 10. A Small Rubber Tube Placed over the...DC motor. A third motor is enclosed in a waterproofed mechanism which supports roll motions. The model is supported in the inverted position in order...entire system, from tunnel velocity to model motion, is driven by a PC based LabVIEW software. B. THE UCAV 1303 MODEL In order to perform a flow

  12. Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors.

    PubMed Central

    Cortinovis, C.; Klimek, F.; Nogueira, E.

    1991-01-01

    application of some carcinogens at high doses, they are not obligatory precursors of hepatocellular tumors. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 21 Figure 22 Figure 23 Figure 24 PMID:1951631

  13. Experimental and clinical observations on massive suprachoroidal hemorrhage.

    PubMed Central

    Lakhanpal, V

    1993-01-01

    in such future studies on massive suprachoroidal hemorrhage. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 FIGURE 25 FIGURE 26 FIGURE 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 FIGURE 32 FIGURE 33 FIGURE 34 FIGURE 35 FIGURE 36 FIGURE 37 FIGURE 38 FIGURE 39 FIGURE 40 FIGURE 41 FIGURE 42 FIGURE 43 FIGURE 44 FIGURE 45 FIGURE 46 FIGURE 47 FIGURE 48 FIGURE 49 FIGURE 51 figure 52 FIGURE 53 FIGURE 54 FIGURE 55 FIGURE 56 FIGURE 57 FIGURE 58 FIGURE 59 FIGURE 60 FIGURE 61 FIGURE 62 FIGURE 63 FIGURE 64 FIGURE 65 FIGURE 66 FIGURE 67 FIGURE 68 FIGURE 69 PMID:8140705

  14. Histopathologic studies of ischemic optic neuropathy.

    PubMed Central

    Knox, D L; Kerrison, J B; Green, W R

    2000-01-01

    FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 A FIGURE 24 B FIGURE 24 C FIGURE 24 D FIGURE 24 E FIGURE 24 F FIGURE 25 A FIGURE 25 B FIGURE 25 C FIGURE 25 D FIGURE 25 E FIGURE 25 F FIGURE 26 FIGURE 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 PMID:11190024

  15. The response of the macaque tracheobronchial epithelium to acute ozone injury. A quantitative ultrastructural and autoradiographic study.

    PubMed Central

    Wilson, D. W.; Plopper, C. G.; Dungworth, D. L.

    1984-01-01

    important participants in the repair of chemically injured airway epithelium; stratification and increased amounts of cytoplasmic filament bundles and desmosomal attachments, rather than being evidence of squamous metaplasia or dysplastic change, might be stereotypic responses of airway epithelium to injury; and the ciliated cell population becomes less susceptible to ozone-induced necrosis with continuing exposure. Images Figure 21 Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 26 Figure 27 PMID:6540523

  16. Cellular pathology of homozygous familial hypercholesterolemia.

    PubMed Central

    Buja, L. M.; Kovanen, P. T.; Bilheimer, D. W.

    1979-01-01

    2 Figure 3 Figure 4 Figure 5 Figure 10 Figure 11 Figure 25 Figure 26 Figure 27 Figure 28 Figure 29 Figure 8 Figure 9 Figure 24 Figure 20 Figure 21 Figure 12 Figure 13 Figure 14 Figure 15 Figure 22 Figure 23 PMID:118674

  17. Constitution and behavior of follicular structures in the human anterior pituitary gland.

    PubMed Central

    Ciocca, D. R.; Puy, L. A.; Stati, A. O.

    1984-01-01

    Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 PMID:6326578

  18. Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape.

    PubMed Central

    White, J. G.; Rao, G. H.

    1998-01-01

    in combination with taxol, inhibited the cold-induced shape change but not dilation of the open canalicular system. Rewarming eliminated open canalicular system dilation and restored lentiform appearance. The results indicate that microtubule coils are the major structural elements responsible for disc shape and its restoration after submaximal stimulation or rewarming of chilled platelets. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 21 Figure 22 Figure 23 Figure 24 Figure 25 Figure 26 Figure 27 Figure 28 Figure 29 Figure 30 PMID:9466587

  19. Mouse bronchiolar cell carcinogenesis. Histologic characterization and expression of Clara cell antigen in lesions induced by N-nitrosobis-(2-chloroethyl) ureas.

    PubMed Central

    Rehm, S.; Lijinsky, W.; Singh, G.; Katyal, S. L.

    1991-01-01

    neoplastic lesions. N-nitroso-methyl-bis-chloroethylurea- and NTCU-induced mouse bronchiolar cell alterations could be an interesting new model to study mechanisms of bronchiolar cell differentiation and tumor formation. Images Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 PMID:1651059

  20. Project CHECO Southeast Asia Report. Search and Rescue Operations in SEA, 1 January 1971 - 31 March 1972

    DTIC Science & Technology

    1972-10-17

    34 ................ 14 Figure 4. HH-43 " Pedro " .. ........... . 15 Figure 5. HC-130P "King" ....... ..... . Y•.•. 16 Figure 6. A-1 "Sandys" Escorting a...HH-43 " Pedros " were assigned to the 37th for the LBR mission. The Pedro helicopters were primarily used in non-hostile environments and were limited...available for combat rescue.9/ 40ARRSq. The 40ARRSq was also equipped with Jolly Green and Pedro helicopters. The squadron moved from Udorn RTAFB to NKP RTAFB

  1. Rugged, Thin GaAs Solar Cell Development. Phase I.

    DTIC Science & Technology

    1986-06-16

    PAGE Figure I n-GaAs/n-Ge Profile 10 Fi’,ure 2 AIGaAs/GaAs/Ge Solar Cell - I - V Curve 12 Figure 3(a) AIGaAs/GaAs/Ge Solar Cell - I - V Curve 14 Figure 3...b) Donor Profile for GaAs on Ge 15 Figure 4 AIGaAs/GaAs/Ge Solar Cell - I - V Curve 17 Figure 5 AIGaAs/GaAs/Ge Solar Cell - I - V Curve 18 Figure 6 I-V

  2. Mammary gland neoplasia in long-term rodent studies.

    PubMed Central

    Russo, I H; Russo, J

    1996-01-01

    in cancer initiation. Comparative studies with the development of the human breast and the pathogenesis of breast cancer have contributed to validate rodent-to-human extrapolations. However, it has not been definitively established what type of information is necessary for human risk assessment, whether currently toxicity testing methodologies are sufficient for fulfilling those needs, or whether treatment-induced tumorigenic responses in rodents are predictive of potential human risk. An alternative to the traditional bioassays are mechanism-based toxicology and molecular and cellular approaches, combined with comparative in vitro systems. These approaches might allow the rapid screen of chemicals for setting priorities for further studies to determine the dose-response relationship for chemical effects at low doses, to assess effects other than mutagenesis and/or tumorigenesis, or to establish qualitative and quantitative relationships of biomarkers to toxic effects. Until there is enough information on the predictive value of mechanism-based toxicology for risk assessment, this approach should be used in conjunction with and validated by the traditional in vivo long-term bioassays. Images Figure 1. Figure 2. Figure 3. Figure 4. Figure 5. Figure 6. Figure 7. A Figure 7. B Figure 8. A Figure 8. B Figure 9. Figure 10. Figure 11. Figure 12. Figure 13. Figure 14. Figure 15. Figure 16. Figure 17. Figure 18. Figure 19. Figure 20. Figure 21. Figure 22. Figure 23. Figure 24. Figure 25. Figure 26. PMID:8899375

  3. Ocular explosion during cataract surgery: a clinical, histopathological, experimental, and biophysical study.

    PubMed Central

    Bullock, J D; Warwar, R E; Green, W R

    1998-01-01

    -bank eyes and the theoretical analyses of this entity show that the pressure required to produce such an injury is much more easily obtained with a 3- or 5-mL syringe than with a syringe 10 mL or larger. CONCLUSIONS: Explosion of an eyeball during the injection of anesthesia for ocular surgery is a devastating injury that may go unrecognized. The probability of an ocular explosion can be minimized by careful use of a syringe 10 mL or larger with a blunt needle, by discontinuing the injection if resistance is met, and by inspecting the globe prior to ocular massage or placement of a Honan balloon. When ocular explosion occurs, immediate referral to and intervention by a vitreoretinal surgeon is optimal. Practicing ophthalmologists should be aware of this blinding but preventable complication of ocular surgery. Images FIGURE 1 Figure 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 PMID:10360292

  4. Acquired mitochondrial impairment as a cause of optic nerve disease.

    PubMed Central

    Sadun, A

    1998-01-01

    . ( Images FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURES 24 FIGURES 25 FIGURES 26 FIGURES 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 PMID:10360310

  5. The ultrastructure of conjunctival melanocytic tumors.

    PubMed Central

    Jakobiec, F A

    1984-01-01

    melanocytes and exhibited more haphazard arrangements of the melanofilaments, which were only partially melaninized. Mitochondria were more numerous than in dendritic melanocytes, and monoribosomes predominated over polyribosomes. Cytoplasmic filaments were inconspicuous. Cells in the immediate subepithelial connective tissue zone had features identical to those of the cells within the junctional nests. Smaller, lymphocytoid cells with less numerous and more rudimentary melanosomes were found in the middle and deeper portions of the lesions.(ABSTRACT TRUNCATED AT 400 WORDS) Images FIGURE 21 FIGURE 22 FIGURE 42 FIGURE 67 FIGURE 1 FIGURE 62 FIGURE 26 FIGURE 29 FIGURE 37 FIGURE 11 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 23 FIGURE 24 FIGURE 25 FIGURE 27 FIGURE 28 FIGURE 30 FIGURE 31 FIGURE 32 FIGURE 33 FIGURE 34 FIGURE 35 FIGURE 36 FIGURE 38 FIGURE 39 FIGURE 40 FIGURE 41 FIGURE 43 FIGURE 44 FIGURE 45 FIGURE 46 FIGURE 47 FIGURE 48 FIGURE 49 FIGURE 50 FIGURE 51 FIGURE 52 FIGURE 53 FIGURE 54 FIGURE 55 FIGURE 56 FIGURE 57 FIGURE 58 FIGURE 59 FIGURE 60 FIGURE 61 FIGURE 63 FIGURE 64 FIGURE 65 FIGURE 66 FIGURE 68 FIGURE 69 FIGURE 70 FIGURE 71 FIGURE 72 FIGURE 73 FIGURE 74 FIGURE 75 FIGURE 76 FIGURE 77 FIGURE 78 FIGURE 79 FIGURE 80 FIGURE 81 FIGURE 82 FIGURE 83 FIGURE 84 FIGURE 85 FIGURE 86 FIGURE 87 FIGURE 88 FIGURE 89 PMID:6398936

  6. Myocardial diseases of animals.

    PubMed Central

    Van Vleet, J. F.; Ferrans, V. J.

    1986-01-01

    seen less frequently; and, in contrast to man, coronary artery disease and myocardial ischemia are rather infrequent in animals. The present review shows clearly that the spectrum of myocardial diseases in animals is enlarging and that many newly recognized diseases are emerging and assuming considerable importance. For example, various heritable cardiomyopathies have recently been described in the KK mouse, cattle, and rats. Increasingly recognized myocardial diseases include cardiomyopathies in cats, dogs, and birds; anthracycline cardiotoxicity; furazolidone cardiotoxicity; ionophore cardiotoxicity; myocardial damage associated with central nervous system injuries; myocardial hypertrophy in Images Figure 1 Figure 2 Figure 45 Figure 46 Figure 47 Figure 48 Figure 61 Figure 62 Figure 63 Figure 64 Figure 79 Figure 75 Figure 76 Figure 77 Figure 78 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 21 Figure 22 Figure 23 Figure 24 Figure 25 Figure 26 Figure 27 Figure 28 Figure 29 & 30 Figure 31 Figure 32 Figure 33 Figure 34 Figure 35 Figure 36 Figure 37 Figure 38 Figure 39 Figure 40 Figure 41 Figure 42 Figure 43 Figure 44 Figure 49 Figure 50 Figure 51 Figure 52 Figure 53 Figure 54 Figure 55 Figure 56 Figure 57 Figure 58 Figure 59 Figure 60 Figure 65 Figure 66 Figure 67 Figure 68 Figure 69 Figure 70 Figure 71 & 72 Figure 73 & 74 PMID:3524254

  7. Advanced Coats' disease.

    PubMed Central

    Haik, B G

    1991-01-01

    further study. Specimens from patients with intraocular hemorrhage should be viewed cautiously, since erythrocytes contain high levels of enolase. Analysis of subretinal aspirates is an extremely accurate method of confirming the diagnosis of Coats' disease. The key diagnostic findings are the presence of cholesterol crystals and pigment-laden macrophages and the absence of tumor cells on fresh preparations. The technique should be reserved for patients where retinoblastoma has been ruled out by all noninvasive means and massive subretinal drainage is anticipated. The natural progression in advanced Coats' disease is toward the development of a blind, painful eye. Spontaneous regression does rarely occur, and some eyes quietly progress to a phthisical state.(ABSTRACT TRUNCATED AT 400 WORDS) Images FIGURE 2 FIGURE 3 FIGURE 4 A FIGURE 4 B FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 FIGURE 25 FIGURE 26 FIGURE 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 FIGURE 32 FIGURE 33 FIGURE 34 A FIGURE 34 B FIGURE 35 FIGURE 36 FIGURE 38 FIGURE 39 FIGURE 41 FIGURE 42 FIGURE 43 FIGURE 44 FIGURE 45 FIGURE 46 A FIGURE 46 B FIGURE 47 A FIGURE 47 B FIGURE 48 A FIGURE 48 B FIGURE 49 FIGURE 50 FIGURE 51 FIGURE 52 FIGURE 54 FIGURE 54 (cont.) FIGURE 55 FIGURE 57 FIGURE 58 FIGURE 59 FIGURE 60 FIGURE 61 FIGURE 62 FIGURE 63 FIGURE 64 FIGURE 65 FIGURE 66 A FIGURE 66 B FIGURE 67 A FIGURE 67 B PMID:1808814

  8. Scar remodeling after strabismus surgery.

    PubMed Central

    Ludwig, I H

    1999-01-01

    limitation of versions, less separation of the tendons from sclera, and thicker appearance of the scar segments. The use of nonabsorbable sutures in the repair procedure reduced the recurrence rate. Histologic examination of the clinical stretched scar specimens showed dense connective tissue that was less well organized compared with normal tendon. In the tissue culture studies, cells cultured from the stretched scar specimens grew rapidly and were irregularly shaped. A high-molecular-weight protein was identified in the culture medium. By contrast, cells cultured from normal tendon (controls) grew more slowly and regularly, stopped growing at 4 days, and produced less total protein than cultured stretched scar specimens. In the animal model studies, the collagenase-treated sites showed elongated scars with increased collagen between the muscle and the sclera, as well as increased collagen creep rates, compared with the saline-treated controls. The use of nonabsorbable sutures in collagenase-treated animal model surgery sites was associated with shorter, thicker scars compared with similar sites sutured with absorbable sutures. CONCLUSIONS: A lengthened or stretched, remodeled scar between an operated muscle tendon and sclera is a common occurrence and is a factor contributing to the variability of outcome after strabismus repair, even years later. This abnormality may be revealed by careful exploration of previously operated muscles. Definitive repair requires firm reattachment of tendon to sclera with nonabsorbable suture support. Images FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 FIGURE 25 FIGURE 26 FIGURE 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 FIGURE 32 FIGURE 33 FIGURE 34 FIGURE 35 FIGURE 36 FIGURE 37 FIGURE 38 FIGURE 39 FIGURE 40 FIGURE 41 FIGURE 42 FIGURE 43 FIGURE 44 FIGURE 45 FIGURE 46 FIGURE 52

  9. Red krypton and blue-green argon panretinal laser photocoagulation for proliferative diabetic retinopathy: a laboratory and clinical comparison.

    PubMed Central

    Blankenship, G W

    1986-01-01

    than the pretreatment acuities with fewer cases having larger losses of vision in the krypton treated group. Loss of peripheral visual field was equal with the two types of treatment having a minimal decrease with the IV-4e isopter, but substantial loss with the I-4e isopter. Additional vitreous hemorrhage rarely occurred in either group, but was slightly more frequent in those treated with krypton. Complete regression was accomplished in most eyes with pretreatment disc and/or NVE in both groups, but persistence of neovascularization was more frequent in those treated with krypton. Overall, the wavelength used seemingly had little effect on the result.(ABSTRACT TRUNCATED AT 400 WORDS) Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 PMID:2438841

  10. Physiology and anatomy of synaptic connections between thick tufted pyramidal neurones in the developing rat neocortex.

    PubMed Central

    Markram, H; Lübke, J; Frotscher, M; Roth, A; Sakmann, B

    1997-01-01

    Images Figure 1 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 Figure 16 Figure 17 Figure 18 Figure 20 Figure 22 PMID:9147328

  11. The influence of salt on the structure and energetics of supercoiled DNA.

    PubMed Central

    Schlick, T.; Li, B.; Olson, W. K.

    1994-01-01

    supercoiled DNA function, not only for closed circular DNA,but also for linear DNA with small looped regions. Images FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 19 FIGURE 21 PMID:7696459

  12. Cultured corneal epithelia for ocular surface disease.

    PubMed Central

    Schwab, I R

    1999-01-01

    from any eye is difficult, making confirmation of such work challenging. 7. The results of the rabbit model suggest that allogeneic grafts may restore a nearly normal ocular epithelial surface to certain ocular surface injuries. Images FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 FIGURE 25 FIGURE 26 FIGURE 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 FIGURE 32 FIGURE 33 FIGURE 34 FIGURE 35 FIGURE 36 FIGURE 37 FIGURE 38 FIGURE 39 FIGURE 40 FIGURE 41 FIGURE 42 FIGURE 43 FIGURE 44 FIGURE 45 FIGURE 46 FIGURE 47 FIGURE 48 FIGURE 49 FIGURE 50 FIGURE 51 FIGURE 52 FIGURE 53 FIGURE 54 FIGURE 55 FIGURE 56 FIGURE 57 FIGURE 58 PMID:10703147

  13. Functional organization of mitotic microtubules. Physical chemistry of the in vivo equilibrium system.

    PubMed Central

    Inoué, S; Fuseler, J; Salmon, E D; Ellis, G W

    1975-01-01

    Equilibrium between mitotic microtubules and tubulin is analyzed, using birefringence of mitotic spindle to measure microtubule concentration in vivo. A newly designed temperature-controlled slide and miniature, thermostated hydrostatic pressure chamber permit rapid alteration of temperature and of pressure. Stress birefringence of the windows is minimized, and a system for rapid recording of compensation is incorporated, so that birefringence can be measured to 0.1 nm retardation every few seconds. Both temperature and pressure data yield thermodynamic values (delta H similar to 35 kcal/mol, delta S similar to 120 entropy units [eu], delta V similar to 400 ml/mol of subunit polymerized) consistent with the explanation that polymerization of tubulin is entropy driven and mediated by hydrophobic interactions. Kinetic data suggest pseudo-zero-order polymerization and depolymerization following rapid temperature shifts, and a pseudo-first-order depolymerization during anaphase at constant temperature. The equilibrium properties of the in vivo mitotic microtubules are compared with properties of isolated brain tubules. Images FIGURE 1 FIGURE 2 FIGURE 5 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 19 PMID:1139037

  14. Reconstruction of the lids of a child with microblepharon and multiple congenital anomalies.

    PubMed Central

    Merriam, J C; Stalnecker, M C; Merriam, G R

    1988-01-01

    The initial stages in the rehabilitation of a male child with severe microblepharon, corneal opacities, bilateral facial clefts, bilateral complete cleft lip and palate, and unilateral syndactyly are described. Review of the literature suggests that severe microblepharon is associated with other craniofacial anomalies, and often the child is stillborn or retarded. Surviving children have been abandoned because of their appearance. The child described in this case appears to be unique because his intelligence is normal, and, to our knowledge, this is the first reported case of penetrating keratoplasty after reconstruction of functional eyelids. The principal problems after corneal grafting appear to have been chronic partial exposure due to inadequate lid length and a poor Bell's reflex and the persistence of a rim of vascularized fibrous tissue around the corneal graft. Future reconstructive surgery is outlined. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20 FIGURE 21 FIGURE 22 PMID:2979029

  15. Ultrastructural lesions of the liver in human peliosis. A report of 12 cases.

    PubMed Central

    Zafrani, E. S.; Cazier, A.; Baudelot, A. M.; Feldmann, G.

    1984-01-01

    Ultrastructural lesions of the liver were studied in 12 patients with peliosis hepatis. This vascular lesion consisted of cavities filled with red blood cells and sometimes lined with an endothelial barrier; the cavities were due to cystic dilatation of the space of Disse and/or sinusoidal lumen. The passage of red blood cells through the endothelial barrier was occasionally demonstrated. Other striking alterations included the presence of numerous blebs on the sinusoidal membrane of the hepatocytes and the existence of multiple cellular layers lining the sinusoids. Perisinusoidal fibrosis appeared on follow-up biopsies in 3 patients. There was no major abnormality of the hepatocytes or of the hepatic venules. These findings suggest that alterations of the sinusoidal barrier might constitute the primary event in peliosis, although secondary changes to increased pressure and hypoxia within the lobules cannot be excluded. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 PMID:6696047

  16. Kinetics and ultrastructural studies of the induction of rat alveolar macrophage fusion by mediators released from mitogen-stimulated lymphocytes.

    PubMed Central

    Sone, S.; Bucana, C.; Hoyer, L. C.; Fidler, I. J.

    1981-01-01

    Treatment of F344 rat alveolar macrophages (AMs) in vitro with cell-free supernatant fluids obtained from concanavalin-A (Con A)-stimulated syngeneic lymphocytes induced extensive fusion. The lymphokine responsible for the fusion of AMs (but not other cells) is here referred to as AM fusion factor (Con-A-MFF). Fusion is dependent on the dose of Con-A-MFF and the population density of AM cultures and occurred 10 hours after Con-A-MFF was added to cultures of normal AMs. Con-A-MFF must interact with AMs for more than 8 hours before full expression of fusion is reached at 24 hours. Using a technique allowing for sequential scanning to transmission electron microscopy analysis of cells, the authors determined the relationship of the morphologic characteristics of the surface and the internal structure of cells fusing to form multinucleate giant cells (MGCs). The process of AM fusion begins with the aggregation of AMs, followed by interdigitation of cell processes. Serial sections of MGCs showed lysosomes associated with remnants of plasma membrane in the cytoplasm. The MGCs contained numerous organelles associated with increased secretory activity of cells. Images Figure 13 Figure 14 Figure 3 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 PMID:7234965

  17. Ultrastructural analysis of contractile cell development in lung microvessels in hyperoxic pulmonary hypertension. Fibroblasts and intermediate cells selectively reorganize nonmuscular segments.

    PubMed Central

    Jones, R.

    1992-01-01

    The current study traces the development of contractile cells in the nonmuscular segments of rat lung microvessels in hyperoxic pulmonary hypertension. New intimal cells first develop into a well-defined layer beneath the endothelium and internal to an elastic lamina. Ultrastructurally, these cells are found to be 1) fibroblasts recruited to the vessel wall from the interstitium and 2) intermediate cells, a population of preexisting vascular cells (structurally between a smooth muscle cell and a pericyte). Early in hyperoxia (days 3 through 7), interstitial fibroblasts migrate and align around the smallest vessels in which an elastic lamina is either absent or fragmentary. These cells then are incorporated into the vessel wall by tropoelastin secretion and the formation of an elastic lamina along their abluminal margin. After day 7, the new mural fibroblasts acquire the features of contractile cells, namely a basal lamina, extensive microfilaments, and dense bodies. In other vessels, as early as day 3 of hyperoxia, intermediate cells within the vessel intima begin to acquire the additional filaments and dense bodies of contractile cells. As hyperoxia continues, each cell pathway gives rise to vessels with distinct intimal or medial layers of contractile cells. In this way, thick-walled 'newly muscularized' vessel segments form adjacent to the capillary bed. Images Figure 1 Figure 5 Figure 6 Figure 7 p1500-a Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 PMID:1466406

  18. Histochemical and ultrastructural studies in fibrodysplasia ossificans progressiva (myositis ossificans progressiva).

    PubMed Central

    Maxwell, W. A.; Spicer, S. S.; Miller, R. L.; Halushka, P. V.; Westphal, M. C.; Setser, M. E.

    1977-01-01

    By light microscopy the subdermal nodule of a patient with fibrodysplasia ossificans progressiva (FOP) had a fibromatoid histologic appearance. The cytoplasm of the cells stained strongly for mannose-rich glycoprotein with the concanavalin A-horseradish peroxidase (con A-HRP) method. The tumors also exhibited abundant hyaluronidase-digestible mucopolysaccharide in the interstitium with various basic staining reagents. This material appeared to consist principally of hyaluronic acid or chondroitin sulfate with few or mainly masked sulfate esters. At the ultrastructural level, cells interpreted as the tumor cells in the subdermal nodule from the patient displayed extremely hyperplastic granular reticulum and well-developed Golgi elements and appeared very active in synthesis and secretion of protein. The material in the dilated cisternae of the granular reticulum stained for glycoprotein with the con-A-HRP method. Macrophages which comprised the other main cell type in the nodules commonly contacted the tumor cells and occasionally evidenced engulfment of these cells. The intercellular matrix of the nonossified subdermal nodule exhibited greatly increased mucosubstance and, by electron microscopy, showed an unusual network of dialyzed iron-reactive acid muco-substance in the interstitium. Images Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figures 15-16 Figure 17 Figure 18 Figure 1 Figures 2-3 PMID:141214

  19. Surgical treatment of obesity: a review.

    PubMed Central

    Fobi, M. A. L.

    2004-01-01

    Obesity is a chronic disease due to excess fat storage, a genetic predisposition, and strong environmental contributions. This problem is worldwide, and the incidence is increasing daily. There are medical, physical, social, economic, and psychological comorbid conditions associated with obesity. There is no cure for obesity except possibly prevention. Nonsurgical treatment has been inadequate in providing sustained weight loss. Currently, surgery offers the only viable treatment option with longterm weight loss and maintenance for the morbidly obese. Surgeries for weight loss are called bariatric surgeries. There is no one operation that is effective for all patients. Gastric bypass operations are the most common operations currently used. Because there are inherent complications from surgeries, bariatric surgeries should be performed in a multidisciplinary setting. The laparoscopic approach is being used by some surgeons in performing the various operations. The success rate--usually defined as >50% excess weight loss that is maintained for at least five years from bariatric surgery--ranges from 40% in the simple to >70% in the complex operations. The weight loss from surgical treatment results in significant improvements and, in some cases, complete resolution of comorbid conditions associated with obesity. Patients undergoing surgery for obesity need lifelong nutritional supplements and medical monitoring. Images Figure 4 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 PMID:14746355

  20. Pulmonary and thoracic macrophage subpopulations and clearance of particles from the lung.

    PubMed Central

    Lehnert, B E

    1992-01-01

    Pulmonary macrophages consist of several subpopulations that can be defined by their anatomical locations as well as by other criteria. In addition to the well-known alveolar macrophages that reside on the alveolar surface, pulmonary macrophages also occur in the conducting airways, in various pulmonary interstitial regions, and, in some mammalian species, in the lung's intravascular compartment. Other thoracic macrophages of relevance to pulmonary defense and some lung disease processes are the pleural macrophages resident in the pleural space and macrophages present in regional lymph nodes that receive lymphatic drainage from the lung. Of the above subpopulations of pulmonary and thoracic macrophages, the alveolar macrophages have received the most experimental attention in the context of the pulmonary clearance and retention of deposited particles. Accordingly, less information is currently available regarding the roles other pulmonary and thoracic populations of macrophages may play in the removal of particles from the lower respiratory tract and associated tissue compartments. This report provides an overview of the various subpopulations of pulmonary and thoracic macrophages, as defined by their anatomical locations. The known and postulated roles of macrophages in the pulmonary clearance and retention of particles are reviewed, with particular emphasis on macrophage-associated processes involved in the pulmonary clearance of relatively insoluble particles. Images FIGURE 1. FIGURE 2. FIGURE 3. FIGURE 5. FIGURE 8. FIGURE 12. FIGURE 14. FIGURE 15. FIGURE 16. FIGURE 17. FIGURE 18. FIGURE 19. A FIGURE 19. B FIGURE 21. FIGURE 22. PMID:1396454

  1. Ultrastructural studies of the gray platelet syndrome.

    PubMed Central

    White, J. G.

    1979-01-01

    The gray platelet syndrome (GPS) is a rare inherited disorder in which peripheral blood platelets are relatively large, vacuolated, and almost devoid of cytoplasmic granulation. In the present study we have evaluated the ultrastructure and cytochemistry of platelets from 2 patients with the GPS to determine precisely which organelles are missing from their cells. The findings indicate that gray platelets contain normal numbers of mitochondria, dense bodies, peroxisomes, and lysosomes but specifically lack alpha-granules. Preliminary studies of megakaryocytes from 1 of the 2 patients suggest that the defect in granule formation may lie at the level of the Golgi zone. Images Figure 15 Figure 16 Figures 17 and 18 Figures 19 and 20 Figure 3 Figure 4 Figures 5 and 6 Figures 7 and 8 Figure 27 Figure 28 Figure 29 Figure 30 Figure 31 Figure 32 Figure 9 Figure 10 Figure 11 Figure 12 Figures 13 and 14 Figures 21 and 22 Figures 23 through 26 Figure 1 Figure 2 PMID:453324

  2. Network Modeling and Simulation Environment (NEMSE)

    DTIC Science & Technology

    2012-07-01

    Loop Using OPNET Modeler Demo ................................................ 3 3.2.3 COPE Demo...11 B 4.3 OPNET ...13 Figure 15: Antenna Pattern in OpNet ............................................................................... 13 Figure 16: NEMSE Box

  3. Rat alveolar myofibroblasts acquire alpha-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis.

    PubMed Central

    Vyalov, S. L.; Gabbiani, G.; Kapanci, Y.

    1993-01-01

    The majority of fibroblasts in alveolar septa are characterized by the presence of cytoplasmic bundles of microfilaments that contain cytoplasmic actin isoforms; these cells have been named contractile interstitial cells or V-type myofibroblasts. In the rat, they express desmin as intermediate filament protein. In this study, we explored the possibility that modulation and replication of such septal fibroblasts result in the appearance of alpha-smooth muscle (alpha-SM) actin-positive myofibroblasts, typical of lung fibrosis. Experimental pulmonary fibrosis was produced by a unique intratracheal instillation of bleomycin to 28 rats. Eight additional rats used as controls received the equivalent volume of saline. Paraffin and frozen sections of lungs were examined at days 1, 3, 5 and 7 after treatment. Microfilaments and intermediate filaments were stained using antibodies against total actin, alpha-SM actin, desmin, vimentin, keratin, and SM myosin. Electron microscopic labeling of desmin and alpha-SM actin using immunogold technique was done on Lowicryl K4M resin-embedded specimens. alpha-SM actin appeared in desmin-positive alveolar fibroblasts as early as 24 hours after intratracheal bleomycin instillation; the modulation of alpha-SM actin in these cells was preceded by a lymphomonocytic infiltration of alveolar septa. Twenty-four hours to 3 days after bleomycin administration, a proliferation of alveolar myofibroblasts occurred. Fibrosis with laying down of collagen fibers took place after the above mentioned cellular modifications. Our results support the view that septal fibroblastic cells can modulate into typical alpha-SM actin-containing myofibroblasts during experimental bleomycin-induced pulmonary fibrosis. In such a modulation a possible role of cytokines, particularly of transforming growth factor-beta, is considered. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14

  4. The soft keratoprosthesis.

    PubMed Central

    Caldwell, D R

    1997-01-01

    appearance. Images FIGURE 1 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 17A FIGURE 17B FIGURE 18 FIGURE 19 PMID:9440192

  5. Acute respiratory bronchiolitis: an ultrastructural and autoradiographic study of epithelial cell injury and renewal in rhesus monkeys exposed to ozone.

    PubMed Central

    Castleman, W. L.; Dungworth, D. L.; Schwartz, L. W.; Tyler, W. S.

    1980-01-01

    The pathogenesis of acute respiratory bronchiolitis was examined in rhesus monkeys exposed to 0.8 ppm ozone fpr 4--50 hours. Epithelial injury and renewal was qualitatively and quantitatively characterized by correlated techniques of scanning and transmission electron microscopy as well as by light-microscopic autoradiography following labeling with tritiated thymidine. Extensive degeneration and necrosis of Type 1 epithelial cells occurred on the respiratory bronchiolar wall during the initial 4--12 hours of exposure. Increased numbers of labeled epithelial cells were present in this region after 18 hours of exposure, and the highest labeling index (18% was measured after 50 hours of exposure. Most (67--80%) of the labeled cells and all the mitotic epithelial cells (22) observed ultrastructurally were cuboidal bronchiolar epithelial cells. Of the labeled epithelial cells, 20--33% were Type 2 epithelial cells. After 50 hours of exposure the respiratory bronchiolar epithelium was hyperplastic. The predominant inflammatory cell in respiratory bronchiolar exudate was the alveolar macrophage. Monkeys that were exposed for 50 hours and allowed to recover in unozonized air for 7 days had incomplete resolution of respiratory bronchiolar epithelial hyperplasia. The results indicate that Type 1 epithelial cells lining respiratory bronchioles are the cell type most sensitive to injury and that both cuboidal bronchiolar epithelial cells and Type 2 epithelial cells function as stem cells in epithelial renewal. Images Figure 16 Figure 17 Figure 18 Figure 19 Figure 20 Figure 21 Figure 22 Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 23 Figure 24 Figure 25 Figure 9 Figure 10 Figure 26 Figure 27 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 PMID:6767409

  6. Products of cells cultured from gliomas. VI. Immunofluorescent, morphometric, and ultrastructural characterization of two different cell types growing from explants of human gliomas.

    PubMed Central

    McKeever, P. E.; Smith, B. H.; Taren, J. A.; Wahl, R. L.; Kornblith, P. L.; Chronwall, B. M.

    1987-01-01

    cell types may increase our understanding of the mechanism of antigenic changes in gliomas and may provide clues to improved therapeutic approaches. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 PMID:3555104

  7. Ultrastructure of the myocardium after pulmonary embolism. A study in the rat.

    PubMed Central

    Cuénoud, H. F.; Joris, I.; Majno, G.

    1978-01-01

    of right-sided failure; it can be correlated with the electrocardiographic abnormalities found in the comparable human condition. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 16 Figure 17 Figure 5 Figure 6 Figure 7 Figure 18 Figure 19 Figure 20 Figure 8 Figure 21 Figure 22 Figure 9 Figure 23 Figure 10 Figure 24 Figure 11 Figure 25 Figure 26 Figure 12 Figure 27 Figure 28 Figure 13 Figure 14 Figure 15 PMID:677269

  8. Hantavirus Pulmonary Syndrome

    PubMed Central

    Zaki, Sherif R.; Greer, Patricia w.; Coffield, Lisa M.; Goldsmith, Cynthia S.; Nolte, Kurt B.; Foucar, Kathy; Feddersen, Richard M.; Zumwalt, Ross E.; Miller, Gayle L.; Khan, Ali S.; Rollin, Pierre E.; Ksiazek, Thomas G.; Nichol, Stuart T.; Mahy, Brian W.J.; Peters, Clarence J.

    1995-01-01

    a newly recognized, often fatal disease, with a spectrum of microscopic morphological changes, which may be an important cause of severe and fatal illness presenting as adult respiratory distress syndrome. ImagesFigure 1Figure 2Figure 3Figure 4Figure 5Figure 6Figure 7Figure 8Figure 9Figure 10Figure 11Figure 12Figure 13Figure 14Figure 15 PMID:7887439

  9. Eduard Jaeger's Test-Types (Schrift-Scalen) and the historical development of vision tests.

    PubMed Central

    Runge, P E

    2000-01-01

    PURPOSE: Eduard Jaeger's original Test-Types were carefully evaluated: (1) to determine whether Jaeger had maintained a consistent standard, (2) to establish the correct Snellen equivalent for Jaeger's Test-Types, (3) to answer the question of why and how the standard was lost, and (4) to compare the visual angle of optotypes to lines of continuous text. METHODS: All original Viennese editions of Jaeger's Test-Types, as well as first generation United Kingdom (UK) and United States (US) versions, were evaluated. Data were collected objectively using a microruler with a 20X loupe and subjectively using a laser distance-measuring device. The data were analyzed using Microsoft Excel. All previous measurements of Jaeger's Test-Types, objective and subjective, collected over the past 133 years were compared to the current data and to each other. RESULTS: The correct Snellen equivalent of Jaeger's Test-Types was determined. The visual angle created from the measurement of the height of lowercase letters, without ascenders or descenders, provides an accurate method of assigning a visual angle of a line of continuous text. Comparing the typefaces used in printing first generation UK and US versions of Jaeger's Test-Types to the Viennese editions provided an explanation for the absence of a consistent standard for Jaeger's Test-Types today. CONCLUSIONS: All 10 versions of Jaeger's original Test-Types are virtually identical and established a gold standard for reading vision tests. Jaeger's standard was lost when his Test-Types were first printed in the UK and the US using local typefaces. The Jaeger standard has been re-established. Visual angles determined using continuous text are comparable to those obtained by using optotypes. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7C FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19A FIGURE 19B p409-a FIGURE 20 FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 FIGURE

  10. Increased atherosclerosis and glomerulonephritis in cynomolgus monkeys (Macaca fascicularis) given injections of BSA over an extended period of time.

    PubMed Central

    Stills, H. F.; Bullock, B. C.; Clarkson, T. B.

    1983-01-01

    , attached to, and penetrating into the intima of the coronary lesions. No correlation was seen between the development of glomerulonephritis and either aortic or coronary artery atherosclerosis. Images Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 Figure 15 PMID:6227252

  11. Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.

    PubMed Central

    Nickoloff, B. J.; Karabin, G. D.; Barker, J. N.; Griffiths, C. E.; Sarma, V.; Mitra, R. S.; Elder, J. T.; Kunkel, S. L.; Dixit, V. M.

    1991-01-01

    transforming growth factor-alpha mRNAs. Further elucidation of the cellular and molecular basis for the genesis and evolution of psoriasis will provide the framework for a better evaluation of the cause and treatment of this skin disease. Images Figure 1 Figure 1 Figure 2 Figure 14 Figure 15 Figure 16 PMID:1702929

  12. 50 CFR Figure 13 to Part 679 - BSAI C. Opilio Tanner Crab Bycatch Limitations Zone

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false BSAI C. Opilio Tanner Crab Bycatch Limitations Zone 13 Figure 13 to Part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL... ECONOMIC ZONE OFF ALASKA Pt. 679, Fig. 13 Figure 13 to Part 679—BSAI C. Opilio Tanner Crab...

  13. 50 CFR Figure 13 to Part 679 - BSAI C. Opilio Tanner Crab Bycatch Limitations Zone

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false BSAI C. Opilio Tanner Crab Bycatch Limitations Zone 13 Figure 13 to Part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL... ECONOMIC ZONE OFF ALASKA Pt. 679, Fig. 13 Figure 13 to Part 679—BSAI C. Opilio Tanner Crab...

  14. 50 CFR Figure 13 to Part 679 - BSAI C. Opilio Tanner Crab Bycatch Limitations Zone

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false BSAI C. Opilio Tanner Crab Bycatch Limitations Zone 13 Figure 13 to Part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL... ECONOMIC ZONE OFF ALASKA Pt. 679, Fig. 13 Figure 13 to Part 679—BSAI C. Opilio Tanner Crab...

  15. 50 CFR Figure 13 to Part 679 - BSAI C. Opilio Tanner Crab Bycatch Limitations Zone

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false BSAI C. Opilio Tanner Crab Bycatch Limitations Zone 13 Figure 13 to Part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL... ECONOMIC ZONE OFF ALASKA Pt. 679, Fig. 13 Figure 13 to Part 679—BSAI C. Opilio Tanner Crab...

  16. Quantum Enhanced Imaging by Entangled States

    DTIC Science & Technology

    2009-07-01

    2009 13 . SUPPLEMENTARY NOTES 14. ABSTRACT The use of entangled states in a prospective standoff imaging sensor has been explored. Specifically... 13 FIGURE 6 UNFOLDED VERSION OF SETUP FOR PSEUDO-THERMAL GHOST IMAGING. ....................... 13 FIGURE 7 SYSTEM...ALONG ATMOSPHERIC PATH. (D)-(E) FFTS OF STARTING AND FINAL DISTRIBUTIONS OF BEAM. ABSCISSA IS IN CYCLES PER METER. ......... 22 FIGURE 13 VARIANCE

  17. 50 CFR Figure 13 to Part 223 - Single Grid Hard TED Escape Opening

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Single Grid Hard TED Escape Opening 13 Figure 13 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND.... 223, Fig. 13 Figure 13 to Part 223—Single Grid Hard TED Escape Opening EC01JY91.060...

  18. 16 CFR Figure 13 to Part 1633 - Labels for Imported Mattress With Foundation

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Labels for Imported Mattress With Foundation 13 Figure 13 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt.1633, Fig. 13 Figure...

  19. 16 CFR Figure 13 to Part 1633 - Labels for Imported Mattress With Foundation

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Labels for Imported Mattress With Foundation 13 Figure 13 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt.1633, Fig. 13 Figure...

  20. 16 CFR Figure 13 to Part 1633 - Labels for Imported Mattress With Foundation

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Labels for Imported Mattress With Foundation 13 Figure 13 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt.1633, Fig. 13 Figure...

  1. Unified Kinetic Approach for Simulation of Gas Flows in Rarefied and Continuum Regimes

    DTIC Science & Technology

    2007-06-01

    Number: WPAFB 07-0761, 21 Dec 2007. 14 . ABSTRACT This report was developed under a SBIR contract. The objective of this effort was to develop a...experiment) .................................... 14 Figure 6 Comparison of the UFS results with DSMC results for the shock wave problem at Mach...5........................................................................................................... 14 Figure 7 Comparison of Tx and Ty for

  2. What Happens When the Supply Chain Breaks? Implications for the Army Supply Chain Under Attack

    DTIC Science & Technology

    2007-11-02

    56 FIGURES Figure 1: Generic SCOR Model ...34.....................................................................................................................9 Figure 3: Define, Measure, Improve Model ...15 Figure 4: DoD SCOR Model

  3. Methods of and system for swing damping movement of suspended objects

    DOEpatents

    Jones, J.F.; Petterson, B.J.; Strip, D.R.

    1991-03-05

    A payload suspended from a gantry is swing damped in accordance with a control algorithm based on the periodic motion of the suspended mass or by servoing on the forces induced by the suspended mass. 13 figures.

  4. Whimsical Path to Math: Implementing the Navigations Series

    ERIC Educational Resources Information Center

    Christy, Donna M.

    2006-01-01

    This article describes lessons that link mathematics topics with literature, the NCTM's Navigations series, and art projects. Each lesson is designed around a theme and is laced throughout with fantasy. (Contains 13 figures.)

  5. Wilbrand's knee of the primate optic chiasm is an artefact of monocular enucleation.

    PubMed Central

    Horton, J C

    1997-01-01

    chiasm. It forms gradually over a period of years following monocular enucleation, presumably from shrinkage of the optic chiasm caused by atrophy of fibers from the enucleated eye. Therefore, the superior temporal hemianopia in the "other eye" seen in the anterior chiasmal syndrome cannot be due to compression of Wilbrand's Knee. I propose that it occurs from combined compression of the optic chiasm and one (or both) optic nerves. Images FIGURE 2 FIGURE 5A FIGURE 5B FIGURE 6 FIGURE 7 A FIGURE 7 B FIGURE 7 C FIGURE 7 D FIGURE 7 E FIGURE 7 F FIGURE 7 G FIGURE 7 H FIGURE 8A FIGURE 8B FIGURE 9A FIGURE 9B FIGURE 10 FIGURE 11A FIGURE 11B FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 16 FIGURE 18 FIGURE 20 PMID:9440188

  6. Ballistic Flash Characterization: Penetration and Back-Face Flash

    DTIC Science & Technology

    2012-03-01

    14 Figure 3: Shot T210 Flash X-Radius vs Time .................................................................. 24 Figure 4: 7075 Set A Model...Cumulative Area ................................................................. 35 Figure 5: 7075 Set A Model Average Area...35 Figure 6: 7075 Set B Model Cumulative Area

  7. High Linearity Wideband Coherent Amplitude Modulation (AM) Radio Frequency (RF)-Photonic Links

    DTIC Science & Technology

    2005-10-01

    HOMODYNE DETECTION............................4 FIGURE 3. A DUAL- BALANCED DETECTOR...STRETCHER WOUND WITH PM FIBER..........................................................................14 FIGURE 10. THE DUAL- BALANCED PHOTODETECTOR...46 FIGURE 35. A SECOND SCHEME FOR BALANCING THE Y-JUNCTION

  8. Coastal Bathymetry Using Satellite Observation in Support of Intelligence Preparation of the Environment

    DTIC Science & Technology

    2011-09-01

    14 Figure 8. Bathymetry of San Diego Harbor estimated by IKONOS (left) compared with Fugro multibeam ......is the ground truth bathymetry of San Diego Harbor as determined six months after the satellite imagery from a Fugro West multibeam SONAR survey

  9. Demonstration and Analysis of Reusable Launch Vehicle Operations

    DTIC Science & Technology

    2006-08-01

    15 Figure 9: P-7B Parachute Recovery...to the Launch Site......................................................... 18 Figure 12: P-7A Flight Profile - From Liftoff to Parachute Deployment...9 Table 6. Updated Model of P-7A Trajectory Events ...................................................... 19 Table

  10. Evaluation of errors due to Compton scattering in gamma-ray emission imaging

    SciTech Connect

    Bruno, M.F.

    1983-12-01

    A set of computer simulation programs were developed to aid in the design of new instrumentation and in the design and evaluation of algorithms for scatter correction in positron emission computed tomography. 14 references, 15 figures, 3 tables. (ACR)

  11. Microstructure and Mechanical Properties of HSLA-100 Steel

    DTIC Science & Technology

    1990-12-01

    13 Figure 4. High Strength Bainite Strength Components .................... 20 Figure 5. Bainitic Steel Tempering and DBTT ...21 Figure 6. Tempered Bainite Steel Yield Stress and DBTT .................. 21 Figure 7. HSLA-100 Steel Yield Strength versus Aging...Energy at -84°C ............... 31 Figure 14. HSLA-100 Steel Lot GQH DBTT ............................ 31 Figure 15. HSLA-100 Steel Lot GQH Ductility

  12. Advanced Technology Demonstrator for IR Imaging Missile Warning System

    DTIC Science & Technology

    2002-02-01

    13 Figure 9: Paraglider ...but also mountains, towers, other flying platform and e.g. paratroopers/ paragliders . Some of these objects have no plume, this excludes UV-devices for...Figure 9: Paraglider - The device also has to have the ability to recognize these a.m. objects, so it has to be an imaging device with intelligent image

  13. Engineering Design Guidance for Detached Breakwaters as Shoreline Stabilization Structure

    DTIC Science & Technology

    1993-12-01

    Lakeview Park shoreline. Combinations of wave height, period, direction, and still-water levels were studied to determine test conditions that produced a...77 Structural Design Objectives ........................... 77 Design Wave and Water Level Selection .................... 77...Chesapeake Bay at Bay Ridge, Maryland ................... 9 Figure 8. Aerial view of Lakeview Park , Lorain, Ohio ......... 13 Figure 9. Detached

  14. Firefighting and Emergency Response Study of Advanced Composites Aircraft. Objective 2: Firefighting Effectiveness of Technologies and Agents on Composite Aircraft Fires

    DTIC Science & Technology

    2011-12-31

    composite fire, AFFF, MIL-F-24835F, UHP , firefighting gel, extinguishment U U U UU 33 Brent M. Pickett Reset i Distribution A: Approved for public...12 Figure 8. (a) Temperature and (b) Total Heat Flux for Representative AA and UHP Test Runs...13 Figure 9. Photograph Following UHP Extinguishment, Showing

  15. A Bayesian Approach to User Stopping Rules for Information Retrieval Systems.

    ERIC Educational Resources Information Center

    Kraft, Donald H.; Waller, W. G.

    1981-01-01

    Presents a dynamic model of user behavior when scanning an information storage and retrieval system output list, compares rules for determining the user's optimum stopping point, presents an algorithm for implementing the Bayesian model, and discusses implications for retrieval system design. Provided are 13 figures and 15 references. (Author/RBF)

  16. Group Collaboration in Organizations: Architectures, Methodologies and Tools

    DTIC Science & Technology

    2002-03-01

    Communication (From Schrage, 1995). ....................13 Figure 2. Collaborative Model (From: Schrage, 1995...At different times Asynchronous Communication : Communication between parties that takes place at different time. The message is sent at one...together as a group Group Support Systems (GSS): Information systems that support the work of groups ( communication , decision making) xvi

  17. Hydrolytic and Peroxyhydrolytic Degradation of Nerve Agent Analogs with Low Molecular Weight Bimetallic Catalysts

    DTIC Science & Technology

    2005-01-01

    sulfuric acid , followed by neutralization and extraction results in 1. While both routes provide 1 in usable percentile yields, the second can be run on...sulfones with periodic acid as the oxygen donor.13 Figure 1. Ball-and-stick representation of catalysts 3a (left) and 3b with counter ions omitted

  18. Micro-Composite Fabrication via Field-Aided Laminar Composite (FALCom) Processing

    DTIC Science & Technology

    2012-09-01

    MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12 . DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution... 12 Figure 9. Schematic of laser and UV mold movements. .............................................................. 12 ...processing apparatus. .........................................................13 Figure 12 . Images of UV photopolymer samples, (l-r): sample with

  19. An Incremental Language Conversion Method to Convert C++ into Ada95

    DTIC Science & Technology

    1996-12-01

    Background ........................................................................... 10 2.1 Software Layer Architecture... 10 2.2 The Object-Oriented Model of RDT ........................................... 12 3. Sum m ary of Current Knowledge... 10 Figure 2. The Object-Oriented Model of RDT ................................. 13 Figure 3. An example to describe the difference

  20. City of Freeport, Florida, State Road 20 Water Main Installation, Final Environmental Assessment, Eglin Air Force Base, Florida

    DTIC Science & Technology

    2010-07-01

    1-5 1.4.2 Potential Issues Studied in Detail .................................................................................................1-6...and Species Occurring Within or Adjacent to the Proposed Action Sites ...............3-13 Figure 3-7. Existing Roads in the Proposed Action Study ...Area (View 1 to 4) .......................................................3-20 Figure 3-8. Existing Roads in the Proposed Action Study Area (View 5

  1. Urban-Small Building Complex Environment: W07US Stability Analysis, Volume AS-3 (Urban Versus Rural Diurnal Stability Cycles)

    DTIC Science & Technology

    2009-09-01

    cirrus . From personal observations, a solar radiometer sometimes has difficulty sensing very thin cirrus clouds . Revising the cause and effects...13 Figure 6. Defining a “case” as a period of stable conditions over consecutive... defined as viii those periods in which the atmosphere transitions between stable and unstable (and visa versa) conditions. Therefore, the time

  2. An Experiment in Collaborative Team Decision Making in Complex Information Processing Environments

    DTIC Science & Technology

    2006-02-28

    researchers.13 Figure 2: Sample MERMAIDS Screen with Incident Map (right side) And Incident Aerial Photograph (left side...SAS: Applications Programming: A Gentle Introduction. Belmont, CA: Duxbury Press. 14 MERMAIDS -- Medical Emergency Response using Military Asset in...an Integrated Decision Support ( MERMAIDS )2. Figure 2 shows a screen capture of the MERMAIDS interface with possible location of incidents and the

  3. Clutter Identification Using Electromagnetic Survey Data

    DTIC Science & Technology

    2013-07-01

    Demonstration at the former Spencer Artillery Range, TN during May 2012. The dynamic test area covered 0.5 Ha of open field. We report the classification...2 Figure 4-1 – Spencer Range demonstration site layout...the MP system for the Dynamic Area at the former Spencer Artillery Range, TN. .....................................13 Figure 7-1 – Data contour

  4. Afghanistan Narcotics: The Bigger Battle Toward Stabilization

    DTIC Science & Technology

    2009-04-01

    65  iv Table of Figures Figure 1. Poppy ...Cultivation in Afghanistan 1996-2006......................................................... 13 Figure 2. Opium poppy cultivation change in Afghanistan...20 Figure 4. Opium Poppy Cultivation in Afghanistan (ha), 2003-2007 .................................... 20 Figure 5. Salaries in Afghanistan

  5. Multiple Strategy Bio-Detection Sensor Platforms Made From Carbon and Polymer Materials

    DTIC Science & Technology

    2007-11-02

    antibodies would bind in a uniform manner to the nitrocellulose-coated slides. In addition it was demonstrated that antibodies that recognize E . coli bacteria can...bacteria in solution. 13 Figure 11: The image on the left is of E . coli bacteria captured by antibodies and the image on the right is of Primary antibody

  6. Aqueous Solution Heat Pipe Transport: Qu-Tube vs. Capillary-Pumped Heat Pipe

    DTIC Science & Technology

    2013-07-01

    9 Figure 5: Progressive IR Images for the V- Meniscus of HP-1(left) and HP-1...N (right) ............................ 10 Figure 6: Progressive IR Images for the V- Meniscus of QT-1 (left) and HP-1 (right...11 Figure 7: Progressive IR Images for the H- Meniscus of QT-1 (left) and HP-1 (right) ............................... 13 Figure 8

  7. Process Improvements for the AH-64 Tail Rotor Vibration Analysis

    DTIC Science & Technology

    2007-06-01

    Free vortex wake (Scully) ! 7. Wind turbine induction flow (rotors only) a 1...Scissor Tail Rotor Variant 7 Figure 4. RPM Sensor Installation (17) 12 Figure 5. Accelerometer and Tachometer Installation locations. (17) 13 Figure...weight adjusted made to the aft pocket. (17) An accelerometer is used to measure the accelerations in vertical direction. An optical tachometer is

  8. 16 CFR Figures 11, 12 and 13 to... - Hemispherical Anvil and Curbstone Anvil

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Hemispherical Anvil and Curbstone Anvil 11, Figures 11, 12 and 13 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Figs. 11, 12, 13 Figures...

  9. 16 CFR Figures 11, 12 and 13 to... - Hemispherical Anvil and Curbstone Anvil

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Hemispherical Anvil and Curbstone Anvil 11, Figures 11, 12 and 13 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Figs. 11, 12, 13 Figures...

  10. 16 CFR Figures 11, 12 and 13 to... - Hemispherical Anvil and Curbstone Anvil

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Hemispherical Anvil and Curbstone Anvil 11, Figures 11, 12 and 13 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Figs. 11, 12, 13 Figures...

  11. 16 CFR Figure 13 to Part 1633 - Labels for Imported Mattress With Foundation

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Labels for Imported Mattress With Foundation 13 Figure 13 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt. 1633, Fig. 13...

  12. 16 CFR Figures 11, 12 and 13 to... - Hemispherical Anvil and Curbstone Anvil

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Hemispherical Anvil and Curbstone Anvil 11, Figures 11, 12 and 13 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Figs. 11, 12, 13 Figures...

  13. 16 CFR Figures 11, 12 and 13 to... - Hemispherical Anvil and Curbstone Anvil

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Hemispherical Anvil and Curbstone Anvil 11, Figures 11, 12 and 13 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Figs. 11, 12, 13 Figures...

  14. 16 CFR Figure 13 to Part 1633 - Labels for Imported Mattress With Foundation

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Labels for Imported Mattress With Foundation 13 Figure 13 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt. 1633, Fig. 13...

  15. Cost Analysis of Electric Grid Enhancement Utilizing Distributed Generation in Post-War Reconstruction

    DTIC Science & Technology

    2009-03-01

    IEEE Spectrum Online Article, "Re-engineering Iraq,” Feb. 2006.)....................................................................5 Figure 5...Capstone Microturbines (Source: Capstone Turbine Coorperation) ..............12 Figure 6: Caterpillar Model 3406C 300kW Reciprocating Diesel...Generator (Source: Caterpillar ) .......................................................................................................13 Figure 7

  16. Piezoelectric Non-linear Nanomechanical Temperature and Acceleration Intensive Clocks (PENNTAC)

    DTIC Science & Technology

    2014-05-01

    13 Figure 15: Microcontroller based...final temperature stability of < 2 ppm from – 40 to + 85 °C was demonstrated for a microcontroller -based ovenized oscillator. Fundamental limits...the resonator center frequency is programmed to be at a particular frequency at a given temperature by storing in the microcontroller the amount of

  17. Breast Cancer Chemoresistance Mechanisms Through PI 3-Kinase and Akt Signaling

    DTIC Science & Technology

    2015-07-01

    PI3K/Akt pathway inhibitors including the PI3K inhibitor (BKM120) and the Akt inhibitor (MK2206) (Figure 13). Figure 12. Hyperactive (A) PI3K or...The PI3K/Akt pathway is hyperactive in more than 70% of breast tumors and is critical for tumor progression and resistance to anti-cancer drugs

  18. Performance Comparison of High Resolution Weather Research and Forecasting Model Output with North American Mesoscale Model Initialization Grid Forecasts

    DTIC Science & Technology

    2012-05-01

    12  Figure 6. Comparison of the 2-m dew point temperature RMSE statistic for Domain 2. .......................... 13...Figure 7. Comparison of the 2-m dew point temperature Bias statistic for Domain 2. ............................. 14  Figure 8. Comparison of the mean sea...for Domain 2. ........................................................................................... 27  Figure 18. Comparison of the 2-m dew

  19. Benchmarking Peer Production Mechanisms, Processes & Practices

    ERIC Educational Resources Information Center

    Fischer, Thomas; Kretschmer, Thomas

    2008-01-01

    This deliverable identifies key approaches for quality management in peer production by benchmarking peer production practices and processes in other areas. (Contains 29 footnotes, 13 figures and 2 tables.)[This report has been authored with contributions of: Kaisa Honkonen-Ratinen, Matti Auvinen, David Riley, Jose Pinzon, Thomas Fischer, Thomas…

  20. Minnesota Health Statistics 1984. [34th Annual Summary Report.

    ERIC Educational Resources Information Center

    Minnesota State Dept. of Health, Minneapolis. Center for Health Statistics.

    This annual summary of vital statistics contains technical notes on changes in the summary format, sources of data, data quality, geographic allocation, and definition of rates. A total of 56 data tables and 13 figures are provided in the areas of: (1) an overview of 1984 vital statistics; (2) live births; (3) reported induced abortions; (4)…

  1. Minnesota Health Statistics 1986. (36th Annual Summary Report).

    ERIC Educational Resources Information Center

    Minnesota State Dept. of Health, Minneapolis. Center for Health Statistics.

    This annual summary of vital statistics from the state of Minnesota contains technical notes on changes in the summary format, sources of data, data quality, geographic allocation, and definition of rates. A total of 63 data tables and 13 figures are provided in the areas of: (1) an overview of 1986 vital statistics; (2) live births; (3) reported…

  2. Understanding Academic Information Seeking Habits through Analysis of Web Server Log Files: The Case of the Teachers College Library Website

    ERIC Educational Resources Information Center

    Asunka, Stephen; Chae, Hui Soo; Hughes, Brian; Natriello, Gary

    2009-01-01

    Transaction logs of user activity on an academic library website were analyzed to determine general usage patterns on the website. This paper reports on insights gained from the analysis, and identifies and discusses issues relating to content access, interface design and general functionality of the website. (Contains 13 figures and 8 tables.)

  3. 50 CFR Figure 13 to Part 223 - Single Grid Hard TED Escape Opening

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Single Grid Hard TED Escape Opening 13 Figure 13 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES...

  4. 50 CFR Figure 13 to Part 223 - Single Grid Hard TED Escape Opening

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Single Grid Hard TED Escape Opening 13 Figure 13 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES...

  5. Fatigue Behavior of a Functionally-Graded Titanium Matrix Composite

    DTIC Science & Technology

    2005-03-01

    6: Buckling guide and teflon strip ........................................................................ 13 Figure 7: Test apparatus...out for the placement of the extensometer. A thin strip of Teflon was placed on either side to minimize friction. Finally, the buckling guide was...attached by finger-tightening four machine screws with nuts and washers. Figure 6: Buckling guide and teflon strip Testing Setup All tests

  6. Code Pulse: Software Assurance (SWA) Visual Analytics for Dynamic Analysis of Code

    DTIC Science & Technology

    2014-09-01

    interface for the Code Pulse dynamic tracer ............. 13 Figure 5. Layout and visualization exploration mockup ...code coverage user interface ........................................................... 23 Figure 13. Mockups of package tree view to control what...involved, we designed the user experience that would satisfy both the use cases and our requirements. This came in the form of low fidelity mockups and

  7. The ocular manifestations of congenital infection: a study of the early effect and long-term outcome of maternally transmitted rubella and toxoplasmosis.

    PubMed Central

    O'Neill, J F

    1998-01-01

    and may vary from blindness and severe mental retardation to minor retinochoroidal lesions of little consequence. Effective solutions for either the prevention or treatment of congenital toxoplasmosis have not been developed in this country but are under intensive and continuing investigation. Images FIGURE 4 FIGURE 5A FIGURE 5B FIGURE 5C FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 FIGURE 15A FIGURE 15B FIGURE 16 FIGURE 17 FIGURE 18 FIGURE 19 FIGURE 20A FIGURE 20B FIGURE 20C FIGURE 20D FIGURE 20E FIGURE 20F FIGURE 20G FIGURE 20H FIGURE 20J FIGURE 20K FIGURE 21 FIGURE 22 FIGURE 23 FIGURE 24 A FIGURE 24B FIGURE 25 FIGURE 26 FIGURE 27 FIGURE 28 FIGURE 29 FIGURE 30 FIGURE 31 FIGURE 32 PMID:10360309

  8. Fatigue Behavior of IM7/BMI 5250-4 Composite at Room and Elevated Temperatures

    DTIC Science & Technology

    2015-03-01

    Tension-Tension Fatigue Tests ...............................................................21 4.2.5 Fully Reversed Fatigue Tests ...10 Figure 5: Example of Steel Reaching the Endurance Limit on S-N Curve [15] ............... 11 Figure 6: Tension-Tension Fatigue Test ...14 Figure 7: Tension-Compression Fatigue Test Specimen. All Dimension are in Inches. All Tolerances are ±0.001 in

  9. Symmetry in Sign Language Poetry

    ERIC Educational Resources Information Center

    Sutton-Spence, Rachel; Kaneko, Michiko

    2007-01-01

    This paper considers the range of ways that sign languages use geometric symmetry temporally and spatially to create poetic effect. Poets use this symmetry in sign language art to highlight duality and thematic contrast, and to create symbolic representations of beauty, order and harmony. (Contains 8 tables, 14 figures and 6 notes.)

  10. Desensitizing Flame Structure and Exhaust Emissions to Flow Parameters in an Ultra-Compact Combustor

    DTIC Science & Technology

    2012-03-22

    14 Figure 2.9: CFD computed radial temperature (K) at UCC exit plane showing potential for multiple peak temperatures...21 x Figure 2.12: Changes in jet plume trajectories based on injection angle ................... 22 Figure...operate above stoichiometric fuel-to-air conditions in order to obtain an appropriate heat release in the combustor to produce the necessary work from

  11. Ballistic Compressor Examination of Electrodeposited Niobium.

    DTIC Science & Technology

    1988-03-01

    Properles of Dense Gaein Experbnental The m odynamicm Volume 11, Experimental Themodynamics of Non-Reacting Fuhds B. LeNeindre and B. Vodar, ed...A47 M -. .15 U. a 013 16 .0 O Sample Ag 14 Figure 4. Location of selected SEM micrographs in relation to channel regions of A9 and A47. The numbering

  12. FY 2009 SERDP Annual Report

    DTIC Science & Technology

    2010-02-01

    Landscape Mosaic Technology to Compliment Coral Reef Resource Mapping and Monitoring; and Weapons Systems and Platforms - Alternative for Perchlorates in...flickering used in coral reef Mosaicing Software ................................ 14 Figure II-4. Riverside Fire Laboratory-Research on transition of...three workshops: Coral Reef Monitoring and Assessment; ASETSDefense: Sustainable Surface Engineering for Aerospace and Defense; and Environmentally

  13. Digest of Education Statistics, 1980.

    ERIC Educational Resources Information Center

    Grant, W. Vance; Eiden, Leo J.

    The primary purpose of this publication is to provide an abstract of statistical information covering the broad field of American education from prekindergarten through graduate school. Statistical information is presented in 14 figures and 200 tables with brief trend analyses. In addition to updating many of the statistics that have appeared in…

  14. Airborne Wind Energy: Implementation and Design for the U.S. Air Force

    DTIC Science & Technology

    2011-03-01

    11 2.3. Jet Streams & Global Wind Patterns...3. A typical jet stream pattern, with two jet streams per hemisphere 17 ............... 14 Figure 4. Wind power density (kW/m 2 ) that was...turbines and airfoils in energy production; in wind towers, limited blade portions (red) contribute predominantly to power production; the kite

  15. Demonstration and Validation of Controlled Low-Strength Materials for Corrosion Mitigation of Buried Steel Pipes: Final Report on Project F09-A17

    DTIC Science & Technology

    2015-12-01

    7 2.3.1 Cathodic protection and monitoring .......................................................................... 7 2.3.2 Corrosion ...3.2.6 Native-soil backfill without cathodic protection (JB6) ............................................. 31 3.2.7 Summary of corrosion data...14 Figure 12. ER corrosion rate versus time for JB1 (flowable fill) with cathodic protection

  16. Ballistics of the 30-06 Rifle Cartridge

    DTIC Science & Technology

    2012-11-30

    Sporting Arms and Ammunition Manufacturer’s Institute ( SAAMI ) specifications is 60,000 psi or 50,000 cup. With modern powders, many commercial loads...2850 fps is also notable, but this load exceeds the SAAMI peak pressure (62,000 psi) for this cartridge at 68,100 psi. (14) Figure 3: A comparison

  17. Pre-Cast Concrete Panels for Contingency Rigid Airfield Pavement Damage Repairs

    DTIC Science & Technology

    2010-06-01

    Figure 16. Swift-Lift Installation into Precast Concrete Panel ..................................................... 14 Figure 17. Wall -Saw Cutting... Wall -saw and walk-behind concrete saw). Table 6 is a precast concrete panel fabrication timeline and Table 7 is precast panel placement timeline...AFRL-RX-TY-TR-2010-0095 PRECAST CONCRETE PANELS FOR CONTINGENCY RIGID AIRFIELD PAVEMENT DAMAGE REPAIRS Reza S. Ashtiani, Christopher J

  18. Point Defect Properties in Iron Chromium Alloys

    DTIC Science & Technology

    2006-09-01

    Creep of Nuclear Fuel Pin Cladding [23]. .....................................17 Figure 16. Diagram of Material Hardening and Embrittlement...Irradiation Creep of Nuclear Fuel Pin Cladding [23] 18 • Radiation hardening and embrittlement. This is a second order phenomenon which is caused by the...Atom in a Crystal Lattice [16]........................................................14 Figure 11. > Interstitial [17

  19. Detection of Microcracks in Trunnion Rods Using Ultrasonic Guided Waves

    DTIC Science & Technology

    2015-07-01

    compress the surrounding concrete and prevent it from experiencing excessive destructive tensile forces. These rods are now experiencing ongoing failures...5 Figure 4. Full-scale 4-rod test bed during construction and concrete ...diameter grease-embedded trunnion anchor rod with concrete termination. ...................... 14 Figure 11. Variation in load and the resulting

  20. Ceramic oxide powders and the formation thereof

    DOEpatents

    Katz, J.L.; Chenghung Hung.

    1993-12-07

    Ceramic oxide powders and a method for their preparation. Ceramic oxide powders are obtained using a flame process whereby two or more precursors of ceramic oxides are introduced into a counterflow diffusion flame burner wherein said precursors are converted into ceramic oxide powders. The morphology, particle size, and crystalline form of the ceramic oxide powders are determined by process conditions. 14 figures.

  1. Prototyping a Web-Enabled Decision Support System to Improve Capacity Management of Aviation Training

    DTIC Science & Technology

    2005-09-01

    image of “Cockpit Charts” as displayed from the NAPP Integrated Production Data Repository (NIPDR) website. Comp/fly day: 60 Outs Cumm : 232 Comp...plan day: 46 IPP Cumm : Outs Cumm : 140 Primary SIT: 100 IPP Cumm : 143 Inter. SIT: 65 Prim Preload:14 Figure 2. Cockpit Charts. (From: Training

  2. Analysis of Alternative Watch Schedules for Shipboard Operations: A Guide for Commanders

    DTIC Science & Technology

    2012-03-01

    Safety Administration POMS Profile Of Mood States PCO Prospective Commanding Officers PEO Prospective Executive Officers PVT Psychomotor... perception (From Murphy, 2002) 14 Figure 7. Performance in the sustained wakefulness condition expressed as mean relative performance and the...briefed to Prospective Commanding Officers ( PCO ) and Prospective Executive Officers (PEO) at the Navy Command Leadership School. Additionally Command

  3. Effects of Prior Aging on the Creep Response of Carbon Fiber Reinforced PMR-15 Neat Resin at 288 C in an Air Environment

    DTIC Science & Technology

    2007-06-01

    14 Figure 6: Shrinkage of T-650-35/PMR-15 composite ...used thermosetting polyimide resins for high-temperature polymer-matrix composite applications. Of the many high-temperature resins, PMR-15 has good...specifications for the use of this material, it was observed that the thermal oxidative stability of PMR-15 composites was not only influenced by the curing

  4. Optimal Wind Corrected Flight Path Planning for Autonomous Micro Air Vehicles

    DTIC Science & Technology

    2007-03-01

    14 Figure 4 - TACMAV Flexible Wings ( Higgs , 2005...fuselage for easy 14 storage in a nine inch diameter tube. These flexible wings reduce the span-wise storage requirements by over sixty percent ( Higgs ...2005). Figure 4 - TACMAV Flexible Wings ( Higgs , 2005) 2.2.2 Equipment Mounts The lightweight TACMAV is equipped with sensors capable

  5. An Investigation of Collaborative Leadership

    DTIC Science & Technology

    2013-01-01

    Disiplined Collaboration ............................................................ 14 Figure 3: Positive Deviance Model...horizontally across other internal and external units and organizations. When we move to a more detailed definition of collaboration, we can further define...shape management approach, Hansen describes how the leader is at the intersection of the organization’s vertical internal efforts and the

  6. Solar Air Heating Metal Roofing for Reroofing, New Construction, and Retrofit

    DTIC Science & Technology

    2013-06-01

    roof, gym wall and roof before the ESTCP project. ......................... 14 Figure 9. Plan view schematic of solar air heating mechanical systems ...16 Figure 10. Schematic of domestic hot water heating system ................................................. 17...Gaffney Fitness Center, located at Fort Meade, Maryland. The solar air heating metal roofing system uses conventional metal roofing in a traditional

  7. Fluid Methods for Modeling Large, Heterogeneous Networks

    DTIC Science & Technology

    2005-08-01

    14 Figure 10: RED vs. PI control ....................................................................................................................................15...80 Figure 60: Implementation of PI controller emphasizing role of operating point q0...81 Figure 61: Comparison of RED and PI control under time-varying and heavy TCP loads ........................................81

  8. Augmenting Naval Capabilities in Remote Locations

    DTIC Science & Technology

    2009-12-01

    waste, and overload . 14 Figure 6. Theory of Constraints. Theory of constraints is utilized to eliminate process variation. In lean, this...trawlers and small freight ships. They used these as “mother-ships” to launch their attacks from. Today, the pirates will tow along two or three skiffs

  9. Evaluation of a Gentex (registered trademark) ORO-NASAL Oxygen Mask for Integration with the Aqualung (registered trademark) Personal Helicopter Oxygen Delivery System (PHODS)

    DTIC Science & Technology

    2008-07-13

    13 8b. Onyx II® Digital Pulse Oximeter...was backed up with an Onyx II pulse oximeter (figure 8b) (Yamaya et al., 2002). Additionally, color vision testing using the Ishihara pseudo...Figure 8b. Onyx II® Digital Pulse Oximeter. 14 Figure 8c. Blue

  10. A Harmonic Motion Experiment

    ERIC Educational Resources Information Center

    Gluck, P.; Krakower, Zeev

    2010-01-01

    We present a unit comprising theory, simulation and experiment for a body oscillating on a vertical spring, in which the simultaneous use of a force probe and an ultrasonic range finder enables one to explore quantitatively and understand many aspects of simple and damped harmonic motions. (Contains 14 figures.)

  11. Exploring Individual Differences in Workload Assessment

    DTIC Science & Technology

    2014-12-26

    15 Figure 4: Operator Workload & Red-line (Adapted from (Cassenti and Kelley 2006)) .. 17 Figure 5: ECG Signal...times and Goal attainment Human Physiologic Response Electrocardiography ( ECG ) and Electrooculography (EOG) 8 NASA-TLX is a multi-dimensional...Electrooculography (EOG) signals, and heart rate (HR) and heart rate variability (HRV) as determined from Electrocardiography ( ECG

  12. A Study to Determine Product Costs for Chemistry Laboratory Tests at Darnall Army Community Hospital

    DTIC Science & Technology

    1986-06-01

    purposes, many test procedures whose time values were identical were grouped together, e.g. all of the Dupont (trademark) automated chemistry analyzer tests...department for use in apportioning indirect expenses. 15 Figure 5. Dupont automated chemistry analyzer tests calcium bilirubin magnesium salicylic acid amylase...case mix cost accounting process ................ 9 4. Workcenter organization .................................... 14 5. DuPont automated chemistry

  13. Development of an Angular Distribution Function for the Study of Atomic Lattice Structures Used in Atomistic Simulation

    DTIC Science & Technology

    1991-03-01

    Structures Used in Atanistic Simulation 6. AUTHOR(S) David Wesley, Capt, USAF 7. PERFORMING ORGA1 NIZATION NAME(S) AND ADDRESS(ES) 8 . PERFORMING...42 7 Appendix A: Program Lattice for Generating Model Lattices ................ 43 8 Appendix B: RDF Fortran Programs...15 Figure 8 : Inner ADF’s for model systems .............................................. 16 Figure 9: Outer ADF’s for model systems

  14. COVERT: A Framework for Finding Buffer Overflows in C Programs via Software Verification

    DTIC Science & Technology

    2010-08-01

    4.2 PANA : Combining Numeric and Predicate Abstraction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 4.3 Numeric Abstraction...15 Figure 10: Bar Chart Showing Comparison of Running Times Between COPPER, BLAST, and PANA as the CHECKER for All Tests...COPPER, and PANA Comparison . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 v | CMU/SEI-2010-TR-029 vi

  15. Enabling Technologies for Point and Remote Sensing of Chemical and Biological Agents Using Surface Enhanced Raman Scattering (SERS) Techniques

    DTIC Science & Technology

    2009-09-01

    silver colloid. .........................15 Figure 10. SEM images of various Bacillus spores on (a) fabricated substrate, (b) Klarite substrate...Figure 12. Comparison of SERS spectra from several Bacillus spore samples collected on Klarite substrates collected on Renishaw system...19 Figure 13. Comparison of SERS spectra from several Bacillus spore samples on FON

  16. Establishment of Maximum Voluntary Compressive Neck Tolerance Levels

    DTIC Science & Technology

    2011-07-01

    neck circumference ............................................................................... 15 Figure 14. Response vs. waist circumference ...Figure 14. Response vs. waist circumference Figure 14 suggests a positive linear trend between maximum average forceand waist circumference (with...between weight and waist circumference (r=0.59) as this population was artificially limited through selection for weight under 150 lbs. None of the

  17. Onboard Stability Control System for a Flapping Wing Nano Air Vehicle

    DTIC Science & Technology

    2009-04-24

    15 Figure 14. Vehicle response to hover command with nitinol actuators and sensors...with nitinol actuators and sensors modeled. An extended Kalman filter has been implemented to estimate the functional roll rate from sensor...Actuators The wing control actuators subcomponent consists of nitinol wires connected to mechanisms that dictate the wing kinematics. These mechanisms

  18. Common Operating Picture and Planning Environment for Disaster Response

    DTIC Science & Technology

    2008-06-01

    New Madrid Seismic Zone spans several states along the Mississippi River. The entire seismic zone is best illustrated by a...CA earthquake. 15 Figure 6. New Madrid Seismic Zone Earthquake Compared to the 1994 Northridge, CA Earthquake For Figure 7, “Red indicates...Department of Natural Resources technical bulletin restates the New Madrid Seismic Zone (NMSZ) potential: 1990 Federal Emergency Management

  19. Network Centric Communications for Expeditionary or Carrier Strike Groups

    DTIC Science & Technology

    2011-12-01

    NETWORK SYSTEM ....................... 15 FIGURE 9 – HYPOTHESIZED OPERATIONAL DESIGN FOR NEXT GENERATION AUTOMATED DIGITAL NETWORK SYSTEM ( ADNS ...Lieutenant Lady Cude (SSC PAC) for information on Satellite Communications, Advanced Digital Network System ( ADNS ) and Naval communications policy and gaps...technologies, processes and policies necessary to provide GIG interoperability have been slowly tested and released by the Defense Information System Agency

  20. Limited Investigation of Active Feel Control Stick System (Active Stick)

    DTIC Science & Technology

    2009-06-01

    at VCORNER .............. 15 Figure 12: Pitch Rate Response to 1.5 g Commanded Force PTI at VHI ......................... 16 Figure 13: Pitch Angle...Response to 1.5 g Commanded Force PTI at VHI ...................... 17 Figure 14: Flight Control System Stick Attributes at VLO...23 Figure 19: Cooper-Harper Ratings for Head Down Display Task ( VHI ) ......................... 24 Figure 20: Fine

  1. A Discovery Process for Initializing Ad Hoc Underwater Acoustic Networks

    DTIC Science & Technology

    2008-12-01

    Bay (near the Seaweb network gateway node). ..................................................................... 15 Figure 11. Bellhop eigenray ...compute the eigenray traces and channel impulse response using code from Torres [18] that employs a Bellhop Gaussian beam tracing acoustic propagation...model. Figure 11 depicts the eigenray traces and channel impulse response for the Halifax trial environment with a transmit frequency of 12 kHz, water

  2. Unmanned Aerial Vehicle-Mounted High Sensitivity RF Receiver to Detect Improvised Explosive Devices

    DTIC Science & Technology

    2007-09-01

    14 E. PICOSCOPE .........................................16 F. SINGLE BOARD COMPUTER .............................17 G. CONCLUSION...ICOM America)......15 Figure 8. Pico Scope 3205. (From Picotech)................16 Figure 9. Single Board Computer ...........................18...controlled by a PC. The High Sensitivity RF Receiver system used a single board computer onboard the TERN for this purpose. Figure 7

  3. Connecting American Manufacturing (CAM)

    DTIC Science & Technology

    2013-12-01

    15 Figure 3 Part Sourcing Process ... process not only had a negative effect on the supplier base, but also decreased the revenue and goodwill of the MFG.com marketplace. MFG.com...provide the DoD with additional qualified suppliers for sole-sourced parts at more cost effective pricing. However, the process proved to be cumbersome

  4. Decomposing Solids to Develop Spatial Sense

    ERIC Educational Resources Information Center

    Obara, Samuel

    2009-01-01

    Three sets of activities are presented in the form of puzzles. These activities focus on students' investigations of three-dimensional models, observing how they look and feel. The improvement of students' spatial sense and conceptual understanding after experiencing the activities is described. (Contains 15 figures.)

  5. Integrated Field-Scale, Lab-Scale, and Modeling Studies for Improving the Ability to Assess the Groundwater to Indoor Air Pathway at Chlorinated Solvent-Impacted Groundwater Sites

    DTIC Science & Technology

    2012-08-01

    Monitoring of Indoor Air Radon Concentrations with Time .................................14 Radon Concentrations in Soil Gas... Radon soil gas concentration contours [pCi/L] ...........................................................15 Figure 13. SF6 in indoor air with a constant...calibrations ect. August 2010- present* *SF6 started in December 2010, Radon started in February 2011 All available soil gas and

  6. Human Factors Assessment of the UH-60M Common Avionics Architecture System (CAAS) Crew Station During the Limited User Evaluation (LEUE)

    DTIC Science & Technology

    2005-12-01

    ratings between seat position and results between instrument flight rule ( IFR ) and visual flight rule (VFR) flights. The mean workload rating for...SART scores for left and right seats.............................................................. 15 Figure 13. Comparison of VFR with IFR SA for...left seat........................................................... 16 Figure 14. Comparison of VFR with IFR SA for right seat

  7. Hearing Is Believing: Dalcroze Solfege and Musical Understanding

    ERIC Educational Resources Information Center

    Thomsen, Kathy M.

    2011-01-01

    Dalcroze solfege engages the ear and the mind in chords, functional harmony, and key relationships, in addition to scales, intervals, and melodies. This article provides an overview of Dalcroze solfege by describing its methodology and by offering sample exercises for beginners as well as advanced students. (Contains 15 figures and 5 notes.)

  8. Environmental Assessment: Proposed Fire Station Little Mountain Test Annex, Utah

    DTIC Science & Technology

    2010-03-19

    deficiencies are related to living areas, size of fire station bays and doors, disinfection facilities, and hazardous materials response capability. Scope...15 Figure 5: State of Utah Recommended Areas of Non-Attainment for Ozone ............................. 16 Figure 6...Protection Association NHPA National Historic Preservation Act NOx Oxides of Nitrogen O3 Ozone OSHA Occupational Safety and Health Administration

  9. Assessing the Impact of Auditory Peripheral Displays for UAV Operators

    DTIC Science & Technology

    2007-11-01

    NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7 . PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Massachusetts... 7 Independent Variables...for the transformed (LN) late arrival reaction times. ......... 15 Figure 7 : The box plots of the number of missed radio calls

  10. The U.S. Air Force-Developed Adaptation of the Multi-Attribute Task Battery for the Assessment of Human Operator Workload and Strategic Behavior

    DTIC Science & Technology

    2010-07-01

    for the lower and upper portion of the gauge. .................................................................................. 5 Figure 006 – A gauge...15 Figure 017 – A Scheduling window with a 5 -minute trial set to a low Tracking difficulty, and 8 Communications events...16 Figure 018 – A Scheduling window with a 5 -minute trial set to a

  11. 50 CFR Figure 15 to Part 223 - Weedless TED Brace Bar Description

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Weedless TED Brace Bar Description 15 Figure 15 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES...

  12. 50 CFR Figure 15 to Part 223 - Weedless TED Brace Bar Description

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Weedless TED Brace Bar Description 15 Figure 15 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES...

  13. Deployer: A Robot-Deploying Robot

    DTIC Science & Technology

    2003-04-01

    6: Bandicoot 11 Figure 7: Deployer mast in a.) retracted, b.) extending, and c.) fully extended positions. 13 Figure 8: Wombat climbing stairs with...mast in a.) retracted, b.)extending, and c.) fully extended positions. 13 Deploy er Outfitting - Wombat The second Urban Robot, Wombat (Fig.8), was...equipped with a single, rear-mounted ISIS transceiver and a Swarm Radio to communicate with all of the Joeys. In addition, Wombat was equipped with

  14. Compact, Low-Noise Magnetic Sensor with Fluxgate (DC) and Induction (AC) Modes of Operation

    DTIC Science & Technology

    2009-07-01

    complete bi-polar cycle, and 20 stacked measurements are selected. Two obstacles to dual-mode operation are magnetic hysteresis in the ferrite cores and...13 Figure 5.2 - Dual mode receiver probe. Left: a photo of the 3-axis probe; Right: details of the probe. Two ferrite core excitation coils...response of coil #1 with different core materials (a) Nanocrystalline bar; (b) Ferrite 78 rods; (c) P-1103 rods

  15. A Conceptual and Analytical Study of the Utility of Speed in Naval Operations. Volume 1

    DTIC Science & Technology

    1976-07-01

    tv.uhitiilotica tn uirinniv y uil 11 lirloutli to frtilt 1.1 ( by the sclvj to In oluch veltilcimnn fl. III, i~Imt ic’l,piani;~ Nva4 Movi ~tuct.’" An...Course 40 ; -30 I .20 Wn~ porn Rangi - 0 1Iwm 10 I i 0 2 𔃻 Purtmer to PurotiO• .J1r.1id R, Ito VI-13 Figure V1-3 Aotual Capture Distance Versau

  16. Best Value Analysis of Tool/Individual Material Readiness List (IMRL) Items for Carrier Air Wing Five (CVW-5) F/A-18 Hornet Squadrons from NAF Atsugi to MCAS Iwakuni, Japan

    DTIC Science & Technology

    2012-06-01

    Coleman, & Hodge , 2011). We use some of their findings for transportation and shipping costs to determine whether there is a cost savings to the Naval...relational map of U.S. military bases in Japan. 13 Figure 10. Relational Map of U.S. Military Bases in Japan (From Debord, Coleman, & Hodge , 2011...aviation accidents since the earliest days of flight, whether it was propeller nicks , tire damage, or tears to airframe fabric, but FOD actually

  17. Proceedings of the Fourth International Workshop on a Research Agenda for Maintenance and Evolution of Service-Oriented Systems (MESOA 2010)

    DTIC Science & Technology

    2011-09-01

    Process 10 Figure 2-2: BPMN Example 11 Figure 2-3: Business Measures Summary 12 Figure 2-4: BPEL Mapping 13 Figure 2-5: Proposed Optimization Loop...a BPMS. Graphical standards in this stage (e.g., business process modeling and notation [ BPMN ], Unified Modeling Language activity diagrams) allow...structured as follows. Section 2.2 introduces the key technologies used in our study, BPMN and business process execution language (BPEL); Section 2.3

  18. Multigenerational Breast Cancer Risk Factors in African-American Women

    DTIC Science & Technology

    1998-10-01

    emotional support provided by family/friends. Further work is in progress to identify BRCA1 gene mutations in women with affected relatives with breast...10 Figures Figure 1. Schematic Diagram of the BRCA2 Gene ............................................ 13 Figure 2A. Family...polymorphic variants in these genes in at-risk African American women. The results of these first studies conducted in three families indicated that

  19. A Personal Computer-Based Head-Spine Model

    DTIC Science & Technology

    1998-09-01

    will be marketed to amusement and theme parks and roller coaster designers to ensure that their roller coasters and mechanical rides are safe. By...14 15 Element Model (original and settled positions) 6-12 Figure 6-15 Head Cervical Spine Simulation- 3G Vertical Accelerations 6-13 Figure 7-1...experimentally determined frequency response of humans to vertical excitation and by creating head-spine models for other primates and comparing the model

  20. Studies and Experiments in Structural Dynamics and Control

    DTIC Science & Technology

    2006-12-30

    11 Figure 6: Closed-Loop Responses Due To Statistical Controller Design......................... 13 Figure 7: Reaction Wheel and Thruster Torques Due...of self awareness. The outline of the research goes as follows. First, a brief modeling of satellite with reaction wheels and thrusters will be...7 shows the control action from both reaction wheel cluster and thrusters. It was noted that the action of statistical controller was large at the

  1. Minimum Release of Tributyltin to Prevent Macrofouling

    DTIC Science & Technology

    1990-10-01

    identify by block number) The minimum release of tni-and dibutyltin has been determined for both barnacles and hydrozoans. The test method involved...prevented hydrozoans from attaching. No minimum release rate could be calculated for the dibutyltin because the flux rates were not high enoughi to achieve a...DATA FOR SETTLEMENT WITH TRI- AND DIBUTYLTIN ........................................... 13 FIGURES 1. Percent settlement of barnacles relative to

  2. Crowdsourcing ISR: A Systems Thinking Approach to Knowledge Dynamics in Intelligence Operations

    DTIC Science & Technology

    2013-09-01

    12 Figure 3. Circular causality of a feedback loop (After Capra , 1996) .............................13 Figure 4. Drawing Hands...management and design ( Capra , 1996). It is through an open systems perspective that this thesis proceeds with its analysis. Taking an open systems...system’s structure and behavior through mechanisms called feedback loops. As explained by Capra a feedback loop is “a circular arrangement of

  3. Evaluation Criteria for Aged Asphalt Concrete Surfaces

    DTIC Science & Technology

    2007-06-01

    extraction / recovery process, and Table 3 pre- sents the results for conventional properties of the AC samples. ERDC/GSL TR-07-18 13 Figure 11...Figure 7, cores were extracted on site and the beams were sawn in the laboratory. Once the in situ modulus was obtained with the PSPA and the cores...were extracted , the sample was sawed and removed, and the hole was patched. Portable seismic pavement analyzer tests The PSPA (Figure 10), developed

  4. Toxicity of DEDGN (Diethyleneglycol Dinitrate), Synthetic-HC Smoke Combustion Products, Solvent Yellow 33 and Solvent Green 3 to Freshwater Aquatic Organisms.

    DTIC Science & Technology

    1987-01-15

    APR edition may be used untl exhausted.SEUIYC.SFATOOPT45AG All other editwmn are obsoet. SCRT QASFCnNO HSP ~ % % %" 9ECUNY CaASIICAION Of rWS PAug 19...Cont’d) Diethyleneglycol Zinc chloride dinitrate Lead chloride Synthetic-HC smoke Cadmium chloride combustion products Arsenic chloride HCL Carbon ...tested as a group, they exhibited only minimal toxicity to Daphnia magna (Table 13; Figure 5). Carbon tetrachloride does not appear to be acutely toxic

  5. Abrasion Testing of Products Containing Nanomaterials, SOP-R-2: Scientific Operating Procedure Series: Release (R)

    DTIC Science & Technology

    2016-04-01

    Possible applications include CNTs incorporated in epoxy or other polymer matrices and TiO2 embedded in concrete . The particle number/mass concentration...i.e., epoxy test samples, CNT reinforced epoxy test samples, commercially available CNTs, concrete disks, plates painted with ENM-containing...show possible release of 30 nm TiO2 particles from self-cleaning concrete . ERDC SR-16-2 13 Figure 3. Total particle concentration released

  6. Spectrally Analyzed Embedded Infrared Fiber Optic Diagnostic of Advanced Composite Propellant Combustion

    DTIC Science & Technology

    2006-05-31

    observations, XM39. This nitramine composite propellant is 76 per cent RDX with most of the balance made up by the binder cellulose acetate butyrate and the...13 Figure 7 Predicted Model Spectrum for Pure Decomposition Gas at 6 atm with a 0.3 cm Absorption Path Length...program of in situ diagnostics and laboratory experiments has led to more advanced models of the gas phase processes in the dark zone and secondary flame

  7. Airborne Laser Systems Testing and Analysis (essals et analyse des systemes laser embarques)

    DTIC Science & Technology

    2010-04-01

    4 EMT-2 Laser Spot Energy Measurement 5-11 Figure 5-5 PILASTER FRCT Target Construction 5-12 Figure 5-6 PILASTER FXDT Target Layout 5-13 Figure 5... energy has been optically collected, obstacle detection/classification is performed through an analog detection of the echoes and two successive analysis ... analysis (i.e., geometry, energy distribution, time analysis ), for the maximum number of pulses (spots) in a sequence, for the PHOENIX NIR camera; and

  8. Scheduling for Cost-Plus Construction Projects. Volume 1. Lessons Learned and PROMAN User’s Guide

    DTIC Science & Technology

    1990-09-01

    Page I Suggested Activity Codes 12 2 Poor Subarea Code Value Definition 13 FIGURES I Primavera Utility Menu 18 2 Confinn Selection Menu 19 3 Project...capacity of 40 megabytes will be needed. There must be space for the PROMAN programs, the PROMAN output files, and Primavera Project Management System...auto- mated systems in use at the NTF office be used, as much as possible, to provide the required data. The N’TF office used the Primavera scheduling

  9. Prevention and Treatment of Heterotopic Ossification

    DTIC Science & Technology

    2012-02-01

    Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14 . ABSTRACT The factors contributing to heterotopic ossification (HO...days after delivery of the AdBMP2 or 13 Figure 14 : Photomicrographs of immunofluorescence staining for MMP-9 (red) neurofilament (green) and von...day after receiving AdBMP2 transduced cells, whereas MMP9 positive cells appeared to be uniformly dispersed within the control tissues (figure 14

  10. A Novel Application of the Point of Aim Trace Feature for the Engagement Skills Trainer 2000

    DTIC Science & Technology

    2011-03-01

    acceleration and changes in ambient pressure (e.g., blast) than the vestibulocochlear organs (and their associated central projections) (Lawson & Rupert...more than 10 percent (%) of troops sustaining concussion or brain injury and somewhere between 5 and 15% developing long term sequelae (Zoroya, 24 May... acceleration just before the shot—an apparent jerked trigger or flinch. 13 Figure 8. EST plot shot with poor aim technique.     Selecting

  11. Periscopic Spine Surgery

    DTIC Science & Technology

    2005-03-01

    3D Internal Organ Position From ................... Wong 2004a: Respiratory Motion Compensation Studies Using............ Wong 2004b: MRI for modeling...to the skin motion stage for tracking ............ 13 Figure 13: Dynamic MRI images of patients acquired during free breathing. The imaging sequence...of these is magnetic resonance imaging ( MRI ). Using dynamic MRI , we are able to capture snapshots of the anatomy during respiration (Figure 13) and use

  12. Dynamic Response Analysis of an Icosahedron Shaped Lighter Than Air Vehicle

    DTIC Science & Technology

    2015-03-26

    results using a modal analysis. The experimental setup designed will allow future research on the interaction between the frame and skin of icosahedron...Icosahedron Frame ( on Right) with Membrane Skin ( on Left)......................... 13 Figure 3: Beam Cross-section for Icosahedron Frame ...LTAV Lighter Than Air Vehicle m Meter M Mass Matrix MATLAB Matrix Laboratory MAV Micro Air Vehicle MPa Megapascal n Mode Number N Number of

  13. Numerical And Experimental Study of the Performance of a Drop-Shaped Pin Fin Heat Exchanger

    DTIC Science & Technology

    2003-06-01

    62 APPENDIX C. SAMPLE NUMERICAL RUN ........................65 APPENDIX D. SAMPLE EXPERIMENTAL RUN .........................67...10 Figure 4. Finite element model ..............................11 Figure 5. Sample Model meshing (X/D=2,S/D=2,L/D=1.2) ........13 Figure 6...the last 10 iterations. 12 Figure 5. Sample Model meshing (X/D=2,S/D=2,L/D=1.2) 5. Solution Technique All

  14. Lightening the Load of a USMC Rifle Platoon Through Robotics Integration

    DTIC Science & Technology

    2014-06-01

    NUMBERS 6. AUTHOR(S) Sian E. Stimpert 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 8...PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING /MONITORING AGENCY NAME(S) AND ADDRESS(ES) N/A 10. SPONSORING/MONITORING AGENCY REPORT NUMBER...13 Figure 4. Basic Rifle Platoon Organization (from Hyper War, 1944) ............................17 Figure 5. Iraq and Afghanistan USMC

  15. Building an Agent Technology for Users of the LOCATE Workspace Layout Tool

    DTIC Science & Technology

    2001-04-30

    the user clicks on a lightbulb alert attached to the interface object for which information has been retrieved and is taken to a Java Window that...Figure la. Lightbulbs Indicating Information Retrieved by LOCATE’s Agent Network ..... 13 Figure lb. Deletion ofWorkstation Lightbulb ...form of a small lightbulb inside the object for which information has been retrieved. By clicking on a lightbulb , the user is taken to a Java

  16. Comparison Of Direct Simple Shear Confinement Methods On Clay And Silt Specimens

    DTIC Science & Technology

    2011-12-20

    Shape of a Rubber Specimen Under Constant Height Direct Simple Shear Condition: (a) strain < 10%, (b) strain >10% (DeGroot et al, 1992...wire-reinforced rubber membrane constructed at the Norwegian Geotechnical Institute (NGI) (Figure 1-3). Figure 1-3 – Direct Simple Shear Confinement...confined specimens using a rubber membrane and aluminum rings. The rings were packed tightly together and the sample was consolidated using lead weights

  17. Separation of Oxygen from Seawater by Membrane Permeation

    DTIC Science & Technology

    1989-03-01

    Availability Codos 3Avd t’l and/or list Special List of Figures Figure 1. Schematic of pervaporation process .................. 2 Figure 2. Schematic...oxygen extraction rate from seawater by pervaporation ....... ....................... 7 Figure 5. Photograph of the experimental set-up for measuring the...12 Figure 9. Pressure drop across pervaporation module as a function of feed water flow rate ................. 13 Figure 10

  18. Application of Satellite-Derived Wind Profiles to Joint Precision Airdrop System (JPADS) Operations

    DTIC Science & Technology

    2010-03-01

    Stirling pulse tube cryocooler (BAE, 2010). A 31 schematic diagram of the AIRS instrument configuration is presented in Figure 13. Figure 14...Technology., March 2007. Hattis, Philip, Kai Angemueller, Thomas Fill, Robert Wright, Richard Benney, and David LeMoine. An In-flight Precision Airdrop...C. Holt, Timothy, J. Schmit, Robert M. Aune, Anthony J. Schreiner, Gary S. Wade and Donald G. Gray. Application of GOES-8/9 Soundings to Weather

  19. An Analysis Tool in a Knowledge Based Software Engineering Environment.

    DTIC Science & Technology

    1986-03-21

    Project Database Record . ...... 111-12 Figure 3.5 User Profile Record ... ........ 111-12 Figure 3.6 Project Save Store Record ..... .. 111-13 Figure 3.7...LOAD PROJECT , SAVE PROJECT, LOAD PROFILE, and SAVE PROFILE. When a save project command is entered by the user, the SAVE PROJECT subfunction stores the...functions allow the user to not have to repeatedly re-enter operating system commands. SAVE PROJECT and LOAD PROJECT save the information into a permanent

  20. Statistical Analysis of Atmospheric Forecast Model Accuracy - A Focus on Multiple Atmospheric Variables and Location-Based Analysis

    DTIC Science & Technology

    2014-04-01

    as the primary variable for this study. The analysis separated the observation station data into three categories: Valleys, Plains, and Mountains ...each of 1 km, 3 km, and observation data ( Mountain ). Surface temperature (K) is indicated along the x-axis...13 Figure 10. Histogram plots for each of 1 km, 3 km, and observation data ( Mountain ). Surface temperature (K) is indicated along the x-axis

  1. Comparison of the 1.5 Mile Run Times at 7,200 Feet and Simulated 850 Feet in a Hyperoxic Room

    DTIC Science & Technology

    2012-03-01

    VO2 max ) Test ......................................... 7 Figure 3 - VO2 Max results for Male, Female and All Subjects. * p...0.001 between Male and Female VO2 ’s. ............................................................. 11 Figure 4 - VO2 Max vs Predicted VO2 Max at 850...and 7,200 Feet ................. 12 Figure 5 - Actual VO2 Max vs Predicted VO2 Max at ALT (7,200 Feet) ....... 13 Figure 6 - VO2 Max vs

  2. Evaluation of Carbohydrate-Derived Fulvic Acid (CHD-FA) as a Topical Broad-Spectrum Antimicrobial for Drug-Resistant Wound Infections

    DTIC Science & Technology

    2014-10-01

    molecular mechanisms during wound healing with CHD-FA. Figure 5. Wound images of rats infected with A. baumannii (ATCC BAA-747) and treated with CHD-FA...host gene expression profiling to better assess the cellular and molecular mechanisms during wound healing with CHD-FA. 13 Figure 6. Wound...expression profiling will be performed to better assess the cellular and molecular mechanisms during wound healing with CHD-FA. 20 Figure 5

  3. Investigation of Failed Components from a 7-in High Altitude Research Program (HARP) Cannon

    DTIC Science & Technology

    2011-11-01

    copper- brazed steel. Figure 20 presents the EDS spectrum obtained from the M174 recoil unit failed tube. Table 1 shows the elemental composition in...cut of the tube. Figure 21 shows the cross section. The single-strip type of spiral-wound and copper- brazed steel tube can be observed on this...of primarily ferrite and is consistent with that expected for this alloy . 14 Figure 21. Cross section of the failed M174 recoil unit tube

  4. Displacement of Tethered Hydro-Acoustic Modems by Uniform Horizontal Currents

    DTIC Science & Technology

    2009-12-01

    surface of a 1097 m deep water column , the MATLAB algorithm needs the cable drag coefficient to be CD = 1.6. The cable shapes are similar and the...being approximately 2000 m long (see Figure 14). Figure 14. Moored case study with spherical float BZ–26 syntactic foam is used as flotation ...spherical float, Nitronic 50B cable, D = 16 mm, s = 2000 m, V = 3 kt, current flows right to left 27 The volume of the flotation material

  5. Corrosion Fatigue of Metals in Marine Environments

    DTIC Science & Technology

    1981-07-01

    Severn River Water ... 82 Figure 73. Effect of Stress Ratio on Corrosion Fatigue of 17 - 4PH Steel (H1100) in Seawater 84 Figure...300 E 200 * n 100 s 0 600 500 400 300 200 100 0 « FIGURE 73. Effect of Stress Ratio on Corrosion Fatigue of 17 - 4PH Steel (H1100) in...14 Figure 16. Schematic of Simple Model for Corrosion-Enhanced Crack Nucleation at Emerging Slip Step 17 Figure 17 . Corrosion

  6. Effective Acquisition Strategies for Systems Engineering and Technical Assistance (SETA)

    DTIC Science & Technology

    2012-07-01

    of which operate in strict accordance with the law and provide products and services to the DoD at competitive prices . The fact is that without...market (i.e., making an economic exchange) beyond that which is reflected in the price of a good or service. In-house provision would eliminate the...laboratories, the private sector followed suit by reducing its defense industrial capacity primarily through mergers and buyouts . 14 Figure

  7. U.S. Army Nurse Membership, Accession and Loss Profiles (1987). Volume 1, Reserves

    DTIC Science & Technology

    1988-12-01

    is given in Table 14. Figure 11 shows this geograpic distribution for all USAR nurses for each individual rank from Second Lieutenant to Colonel. The...location of medical units or a recruiting/attrition The geograpic distribution of TPR locations for AING nurses differed from that of the USAR. Members...characteristics would also be helpful for market segmentation research. In addition, family configuration data would aid recruiters as well as policy makers c

  8. A-10 Thunderbolt II (Warthog) Systems Engineering Case Study

    DTIC Science & Technology

    2010-01-01

    The A-1E Skyraider (L) and A-37A Dragonfly (R) .......... 14 Figure 7. Army’s AH-56 Cheyenne...integrating varied functional data will be emphasized. When they are taken together, the student is provided real- world , detailed examples of how the...history and experiences in World War II by both the Allied and Axis powers had helped shape the doctrine of the Air Force to emphasize strategic

  9. Population Viability Analysis of the Endangered Shortnose Sturgeon

    DTIC Science & Technology

    2011-12-01

    overlaid on a Google satellite map that indicates barren training areas (dotted outline) on Fort Stewart. Note also the contrast between developed...Creek confluence and downstream of a large, barren area used for training. Figure 18. Water chemistry measurements from headwater watersheds on Fort...PVA. 14 Figure 7. Schematic map of bridge sample locations overlaid on a Google satellite map that indicates barren training areas (dotted

  10. Functional Rehabilitation With a Foot Plate Modification for Circular External Fixation

    DTIC Science & Technology

    2013-04-05

    return-to-duty rates in service members participating in the RTR and using a novel custom orthosis . This may ultimately translate into higher return-to...secondary to back pain, separated from the Army Abbreviation: IDEO, intrepid dynamic extraskeletal orthosis .14 Figure 6. The white arrow demonstrates a break...Owens JG, et al. Can an ankle- foot orthosis change hearts and minds? J Surg Orthop Adv. 2011;20(1):8-18. 15. Patzkowski JC, Owens JG, Blanck RV

  11. Investigation of Impact Load Absorption through Suspension Line Elongation

    DTIC Science & Technology

    1952-12-01

    16 1. Charts . . ’ . . . .. . . 16 2. glong~tion Ratin of Li; Goups . . . 163. Graphs . .. .. .. .. .. .. .. ... . 16 SECTION IV - DISCUSSION OF...Tester . ...................... z14 Figure 16 . Frazier Air Porosity Tester in Use ....... 215 Figure 17. 30 ft., Extended Skirt CsnoW’ in Deployment Bag...line than on canopies strung with high elongation line. WMADR 5&~5T 1 CONCLUSIONS; 15. Nylon is superior to fortisan in shock absorbing capacity. 16

  12. Controlled Tests of Educators and Submersible Pumps

    DTIC Science & Technology

    1994-09-01

    Waterways Experiment S.ation CatellEing -in-Publication Data Controlled tests of eductors and submersible pumps / by James p . Clausner ... [et al...14 Figure 13a. Sample test data collected by the computer ............ 16 Figure 14. Pull-out test of DRP eductor...20 Figure 15. One-minute average production rates for the DRP and Indian River Inlet eductors ........................ 26 Figure 16 . One-minute average

  13. Modeling Heterogeneous Carbon Nanotube Networks for Photovoltaic Applications Using Silvaco Atlas Software

    DTIC Science & Technology

    2012-06-01

    14 Figure 9. The spectral responses of gallium indium phosphide (GaInP), gallium arsenide (GaAs), and germanium (Ge) solar cells are graphed...power was not created until 1954 when Chapin, Fuller, and Pearson developed a silicon based solar cell for Bell Labs. Since the creation of the...top layer of a Gallium Arsenide (GaAs) solar cell which was simulated in ATLAS software. 3 II. BACKGROUND The use of CNTs to improve the

  14. Circularly Polarized Measurements of Radar Backscatter from Terrain.

    DTIC Science & Technology

    1980-02-01

    Figure 2:. Entrance to Mark Twain National Forest in Southern Missouri ....... ...................... ... 14 Figure 3: Site 2--an area of shortleaf pine...conditions). The tree measurements were completed in Mark Twain National Forest in Southern Missouri (sites 1-6); the road-surface measurements were...measurements for this program were completed at six sites in the Mark Twain National Forest in Southern Missouri during August and again in November of

  15. Tactile Instrument for Aviation

    DTIC Science & Technology

    2000-07-30

    of cat sensory development (from Turner and Bateson , 1988).............................14 Figure 12: Helmet mounted tactile display (from Morag, 1987...Matthews and Gregory , 1999; Braithwaite, Groh, and Alvarez, 1997). The cost of spatial disorientation mishaps also includes mission failure, the...3 4 5 6 7 8 9 10 11 12 Conception Gestation Birth Figure 11: Ontology of cat sensory development (from Turner and Bateson , 1988). 3

  16. Analysis of Voltage and Current Signal Processing in a Li-ion Battery Management System

    DTIC Science & Technology

    2010-09-01

    Results. .......................................................14 Figure 11. Inverting OPAMP Frequency Response...FPGA Field Programmable Gate Array LCS Littoral Combat Ship MOSFET Metal Oxide Semiconductor Field Effect Transistor OPAMP Operational Amplifier...Probe LEM OPAMP DC Value 30 kHz Test Results. DC Value is the DC Component of OPAMP Signal xix 0 0.5 1 1.5 2 2.5 3 3.5 x 10 -4 0 1 2 3 20

  17. Agile Methods in Air Force Sustainment: Status and Outlook

    DTIC Science & Technology

    2014-07-01

    reproduced with permission from Mountain Goat Software and Mike Cohn; adaptations added in unshaded boxes) [ Mountain Goat Software 2005] 14 Figure 4: Types...the original figure from Mountain Goat Software to include the first four ceremonies of the above list. More information on Scrum can be found from...Demonstrations Sprint Retrospective Figure 3: Key Elements of Scrum (reproduced with permission from Mountain Goat Software and Mike Cohn; adaptations

  18. Experimental Evaluation of the Corrosive Potential of Flux Residue Cleaning Agents.

    DTIC Science & Technology

    2007-11-02

    0.0003 inch) pitting corrosion was detected on the aluminum casing components that were cleaned with the water-based deter- gent cleaner and coated with... Corrosion Pitting on Specimen 7212 ......... 14 Figure 4. Photomicrograph Documenting Corrosion Damage on Surface of Specimen 6123...specimens, the maximum depth of pitting corrosion attack measured less than 0.001 inch which represents less than two percent of the specimens available

  19. The status of electric industry restructuring

    SciTech Connect

    Morey, M.

    1996-12-31

    This presentation discusses current electric utility regulatory reform with a focus on the impacts of competition in the Midwest marketplace. Information and data are presented through 14 figures and 30 tables. Regulatory issues at the state and Federal levels are very briefly outlined, including reciprocity, unbundling, stranded cost recovery, and independent system operation. Graphical data on energy capacity by source, capacity additions, wholesale markets, electricity prices, and market development are also presented.

  20. Applications of Ion-Beam Milling and Deposition Techniques to HEL (High Energy Laser) Optics.

    DTIC Science & Technology

    1981-11-23

    using a Twyman -Green interferometer with one leg in the vacuum deposition chamber ........ ...................... .. 14 Figure 3. Deomonstration of...of beam current and voltage. 13 b) I Figure 2. Photographs of interference pattern produced using a Twyman -Green interferometer with one leg in the...Measurements of optical surface roughness were made versus milling depth for various ion beam conditions and geometry arrangements. A Twyman -Green

  1. Multiplexed fluorescence detector system for capillary electrophoresis

    DOEpatents

    Yeung, E.S.; Taylor, J.A.

    1994-06-28

    A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis. 14 figures.

  2. Next Generation Data Collection System for Mobile Detection and Discrimination of Unexploded Ordnance

    DTIC Science & Technology

    2008-09-10

    a bicycle wheel that was attached to the RAP and which was in constant contact with the ground. For one run, when the system was moving at a brisk 2...bike wheel encoder assembly..................................................................................14 Figure 6: Bicycle wheel assembly mounted...use purposely built tow-vehicles and trailers and both deploy arrays of Geonics EM61 metal detectors and total-field magnetometers. The main

  3. Hardware Model of a Shipboard Generator

    DTIC Science & Technology

    2009-05-19

    together and connecting them in series electrically provides a rated capacity of 4 HP. Figure 3: Coupled Motors 14 Figure 4: Motor Nameplate... Series programmable DC power supplies were chosen from lab inventory to meet this requirement. The power supplies were placed in a parallel master-slave...voltage IM = armature current RM = armature resistance VC = counter voltage (back electromotive force) If the magnetic field is

  4. Micromachined Precision Inertial Instruments

    DTIC Science & Technology

    2003-11-01

    and vacuum packaging techniques to achieve degree-per-hour inertial micro-gyroscopes. A single-wafer, all-silicon, high aspect-ratio p...Although vacuum packaging substantially reduces the mechanical noise of a surface micromachined accelerometer and lowers the output noise floor...it is desirable to operate sensors in atmosphere since vacuum packaging is not cost effective [15]. Figure 10: Performance improvements for In

  5. The Use of an Ultra-Compact Combustor as an Inter-Turbine Burner for Improved Engine Performance

    DTIC Science & Technology

    2014-03-27

    flame speed at the reference condition. For the 500g case, the flame structure changes significantly, creating a mushroom vortex and propagating at a...fluid against the outer circumference of the cavity, while the lighter combustion products migrate toward the inner circumference. This contributes...the ITB engines is a product of limiting the main burner exit temperature. 21 Figure 17: T-s Diagram of a Gas Turbine Engine with an ITB [15] Figures

  6. Chemotherapy and Drug Targeting in the Treatment of Leishmaniasis

    DTIC Science & Technology

    1989-05-30

    15 Figure 2. Distribution of Cutaneous and Mucocutaneous Leishmaniasis (6). . . . . . . . . . . . . . . 16 Figure 3. Chemical Structunesof Purine...braziliensis (5,6). 3. Cutaneous Leishmaniasis: presents as open, ulcerated lesions on the skin. This form generally heals spontaneously over a period of...the incurable "diffuse cutaneous leishmaniasis’, a condition similar to leprosy (4). ELOw lner4M.:)ty 0. a rodlc CaseS Figure 1. Distribution of

  7. Defense Contract Management: DOD’s Lack of Adherence to Key Contracting Principles on Iraq Oil Contract Put Government Interests at Risk

    DTIC Science & Technology

    2007-07-01

    cost reductions attributable to its audit findings. We compared the sustention rates on DCAA’s 11 RIO I contract audits to the sustention rates...for 100 DCAA audits of other Iraq contract actions, and found that the sustention rates varied widely for both groups. DOD’s Army Corps of Engineers...Figure 1: Reasons for DCAA Questioned Costs 8 Figure 2: Elapsed Days from Notice to Proceed to Definitization 15 Figure 3: Comparison of Sustention

  8. Maximum Likelihood Fusion Model

    DTIC Science & Technology

    2014-08-09

    data fusion, hypothesis testing,maximum likelihood estimation, mobile robot navigation REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT...61 vi 9 Bibliography 62 vii 10 LIST OF FIGURES 1.1 Illustration of mobile robotic agents. Land rovers such as (left) Pioneer robots ...simultaneous localization and mapping 1 15 Figure 1.1: Illustration of mobile robotic agents. Land rovers such as (left) Pioneer robots , (center) Segways

  9. Investigation of the Interface Phenomena Due to Interaction of High Intensity Stress Waves with Geologic Boundaries

    DTIC Science & Technology

    1991-11-30

    shockwave ........................ 10 Figure 5. Stress-density data fit for gray granodiorite ........... 15 Figure 6. Stress-density data fit for NTS...types were dry NTS tuff, gray granodiorite , and limestone, [5] and [6]. The data obtained in Ref. [5] were obtained from high pressure die assemblies...The results are shown in Figures 5 - 7. The data fit analysis for granodiorite resulted in two curves passing through the data points. The first curve

  10. Minutes of the Explosives Safety Seminar (23rd) Held at Atlanta, Georgia on 9-11 August 1988. Volume 1

    DTIC Science & Technology

    1988-08-01

    evce Securing the lift truck load was also considered for mitigating the accident involving a drop which resulted in a detonation. Using battery...15 1/30 < a/z < 1/15 1.0 >15 > 1/15 Figur. 4 Pressurs-Ir.oulse Relation fnP Stpl A2m 407 p peak applied pressure (F/L 2 ) i applied specific impulse

  11. Biological and aerodynamic problems with the flight of animals

    NASA Technical Reports Server (NTRS)

    Holst, E. V.; Kuchemann, D.

    1980-01-01

    Biological and aerodynamic considerations related to birds and insects are discussed. A wide field is open for comparative biological, physiological, and aerodynamic investigations. Considerable mathematics related to the flight of animals is presented, including 20 equations. The 15 figures included depict the design of bird and insect wings, diagrams of propulsion efficiency, thrust, lift, and angles of attack and photographs of flapping wing free flying wing only models which were built and flown.

  12. Airblast Attenuation Experiments for the M-X Trench.

    DTIC Science & Technology

    1978-12-31

    Reynolds number ReD and large sandgrain roughness ks, the friction coefficient Cf’is independent of Reynolds number. Under MX prototype conditions...transverse ribs in the MX trench, an equivalent sandgrain roughness k= exp 2.5 (2) and R is determined from empirical curves of Dalle-Donne and Meyer...formula for rough pipes ........ . 15 Figure 3. East facility ...... ................ . 20 Figure 4. NASA Ames electric arc shock tube schematic . 21

  13. The Rise of Robots and the Implications for Military Organizations

    DTIC Science & Technology

    2013-09-01

    Drones, Bots, Unmanned Systems, Unmanned Aerial Vehicle, Unmanned Ground Vehicle, Unmanned Surface Vehicle, Unmanned Underwater Vehicle, Exoskeleton ...2 exoskeleton . Cyberdyne’s HAL-5 is shown in Figure 8. 15 Figure 8. Cyberdyne’s HAL-5 (From Cyberdyne). 16 THIS PAGE INTENTIONALLY LEFT...their human operators are also considered T-bots. Ironman’s exoskeleton suit could represent the evolutionary goal for manned T-bots. Given the

  14. Spectrometer for measuring the concentration of components in a fluid stream and method for using same

    DOEpatents

    Durham, M.D.; Stedman, D.H.; Ebner, T.G.; Burkhardt, M.R.

    1991-12-03

    A device and method are described for measuring the concentrations of components of a fluid stream. Preferably, the fluid stream is an in-situ gas stream, such as a fossil fuel fired flue gas in a smoke stack. The measurements are determined from the intensity of radiation over a selected range of radiation wavelengths using peak-to-trough calculations. The need for a reference intensity is eliminated. 15 figures.

  15. Map Classification In Image Data

    DTIC Science & Technology

    2015-09-25

    sub-classes. . . . . . . . . . . . . . . . 15 Figure 3.2 Architecture of a deep CNN. . . . . . . . . . . . . . . . . . . . 24 Figure 4.1 Examples of...22 Table 3.4 Experimental setup for four runs to examine the deep CNN BVLC Reference CaffeNet...images called positives, di- vided into sub-classes including basic maps, pilotage charts, web maps, and sketches. Ad- ditionally, 1,200 images without

  16. Advanced Methods for Passive Acoustic Detection, Classification, and Localization of Marine Mammals

    DTIC Science & Technology

    2014-09-30

    in the case of aerial surveys, significantly dangerous . In both the areas critical to the Navy and in other areas critical to marine mammals, PAM... animal calls via hyperbolic methods, Journal of the Acoustical Society of merica 97, 3352–3353 (1995). Morrissey, R. P., J. Ward, N. DiMarzio, S... animal as it follows its prey just prior to capture. Figure 6: Example of tracking highly ambiguous localizations. 15 Figure 7

  17. NPS AUV Integrated Simulator

    DTIC Science & Technology

    1992-03-01

    147 3. GRAPHIC OBJECT MODEI’QUSING OBJECTFILE FORMAT (cIF)...................... ........... 149. APPENDIX -C. NPS, AUV SONAR CLASSIFICATION SYSTEM...Monterey Bay .. 15 Figure 2.8 Graphics simulation for NPS AUV sonar visualization .......... 15’ Figure 3.1 Integrated simulator network physical...3.11 Integrated simulation display of AUV minefield searh ........ 39 Figure4.1 NPS AUV sonar beam profiles in the NPS pool .......... 43 Figure 42 NPS

  18. Restoring the Nexus of History-Theory-Doctrine in Military Thought: Implications for the Republic of Korea Army

    DTIC Science & Technology

    2013-05-23

    and an ironclad warship known as a Turtle Ship. As stated above, the traditional military thought of Korea was well developed and could achieve...34- 35. 15 Figure 1. The Turtle Ship (Geobukseon) and Multiple Rocket Launcher (Hwacha...Misfortunes: The Anatomy of Failure in War. 1st ed. New York: Vintage Books, 1991. Collins, Jim. Good to Great: Why Some Companies Make the Leap and Others

  19. Efficacy of Two Novel Anodic Coatings for Enhanced Corrosion Protection of Aluminum Armor Alloys

    DTIC Science & Technology

    2014-01-01

    dolly pulled off at 1980 psi. .....................................................................................................15 Figure 17. ASTM D...tests were performed using a loading fixture commonly referred to as a “ dolly .” The dolly is secured normal to the coating surface using a cyanoacrylate...adhesive. After allowing the adhesive to cure for 24 h at 25 °C at 50% relative humidity, the attached dolly was inserted into the test apparatus

  20. Data Integration: Charting a Path Forward to 2035

    DTIC Science & Technology

    2011-02-14

    15 Figure 5: Data Architecture and Semantic Integration Framework……………………………...16 Figure 6: Depiction of...leadership and ability to execute. 6 Gartner defines the discipline of data integration as ―practices, architectural techniques and tools for...knowledge creation becomes possible. Finally, data models are the backbone of data architecture and are necessary, but also a key challenge to

  1. Inventory of Physical and Cultural Elements, Middle Mississippi River Floodplain (River Reach - St. Louis, Missouri, to Cairo, Illinois)

    DTIC Science & Technology

    1975-01-01

    poultry farming. The province is unglaciated, and the uplands generally are covered by a shallow thickness of residual clay soil changing to...Illinois) and becomes less pronounced towards Olive Branch" (a • Within the Tertiary period approximately T to 50 million years ago. 15 Figure 2...strongly rolling area is west of Olive Branch. In most places the soils formed in depressions in loess that is between 20 and 30 ft thick over

  2. Cold Flow Diluent Mixing Study Using Radial High Density Ratio Jets into a Circular Freestream

    DTIC Science & Technology

    2010-07-01

    CAD) solid models. From the CAD model, computational grids are generated for the CFD simulations using Gridgen v.15. Appropriate flow modeling...release, Distribution is unlimited 4 Figure 2: Geometry and Mesh Boundaries in Water Jet Simulations Grid Generation and Flow Model GRIDGEN v.15...generated using GRIDGEN v.15. Figure 4 shows the computational domain for the dual-jet configuration. The modeled domain contains 1.3 to 1.8

  3. Do-it-yourself guideline for constructing a solar alcohol distillation system

    SciTech Connect

    Kennedy, B.W.

    1982-07-27

    The development and testing of a solar powered distillation system are described. The system consists of a parabolic dish collector, a two axis sun tracking stand, sun tracking solar cell system, condenser, fermentation tanks, and continuous distillation still. The assembly instructions for the parabolic dish are included as well as the basic steps to follow in mashing and fermenting of corn meal. 15 figures. (DMC)

  4. An Evaluation of the Technical Feasibility of the Packed Tower Advanced Oxidation Process for the Removal and Destruction of Contaminants from Water

    DTIC Science & Technology

    1996-06-01

    reactor unit. This last factor is of particularly great importance since it largely determines the size and basic design of the reactor. Levenspiel (6... Levenspiel , 6; Charpentier, 15). Figure 2 represents the concentration profiles across a phase boundary for each reactant as envisioned by film theory. A...of steps in series, the rate is governed by the slowest step ( Levenspiel , 6). If the chemical reaction is extremely rapid (essentially instantaneous

  5. Human Infrastructure Detection and Exploitation (HIDE)

    DTIC Science & Technology

    2009-11-01

    Ammonia-based agents used for cleaning, etc., can be detected using chemical sensors. Other chemicals, like cockroach killer, methane, etc., might...people by observing whether some of the machines are in use in a location or building. In this experiment, we will operate a drilling machine and a band ...15 Figure 12. Machine experiment setup. Experimental Setup: • Place IR imagers focusing on the drill/ band saw at about 16 ft from the

  6. Solving Inverse Problems for Mechanistic Systems Biology Models with Unknown Inputs

    DTIC Science & Technology

    2014-10-16

    the therapy is extremely difficult [9]. Other drug therapies, including pain medicine, vasopressors and type 2 diabetes mellitus , basically suffer...interrelationships between tesaglitazar exposure and renal function in patients with type 2 diabetes mellitus ,” J. Clin. Pharmacol., vol. 52, pp. 1317–1327...including mechanistic modeling studies in cancer chemotherapy (e.g., [12, 13]), anti- diabetic drugs (e.g., [14]) and HIV (e.g., [15]). Figure 1

  7. Thermal Battery Operating Gas Atmosphere Control and Heat Transfer Optimization

    DTIC Science & Technology

    2012-09-01

    Approved for public release; distribution unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT The effects of gases and gas mixtures on global...highly effective in atmospheres of pure hydrogen and are potentially useful in mixtures of hydrogen and air. Barium chromate (BaCrO4) placed in contact...15 Figure 9. Gas gettering from a 79.6/20.4 volume percent hydrogen/air mixture

  8. Laser Doppler Velocimetry Measurements Across A Normal Shock In Transonic Flow

    DTIC Science & Technology

    1993-03-01

    15 A. SUPERSONIC WIND TUNNEL ..... ............. .. 15 B. LASER DOPPLER VELOCIMETRY SYSTEM ........... .. 20 1. Laser and Optics...of instability or high velocity gradients. Studies done on particle lag prediction, Chesnakas and Andrew [Ref. 15 ], and particle dynamics effects on...form the convergent-divergent nozzle and test 15 Figure 5. Supersonic Wind Tunnel CONVERGENT. D•VRGENT CONTROL VALVE SBLEtO TEST SECTION CONTROL VALVE

  9. Improved Processing, Analysis and Use of Historical Photography

    DTIC Science & Technology

    2010-10-01

    11 Figure 4. New Mexico and Texas study site locations ......................................................... 15 Figure 5...Mexico and two sites were located in Texas . The sites provided a wide range of sizes, spanning from 1 to 774 square miles. A comparative analysis of...demonstration. Six of the sites were located in New Mexico, and two were in Texas . Figure 4 presents a map of the study site locations. These sites

  10. The Acousto-Optic Interaction in an Infinite Slab of Isotropic Material,

    DTIC Science & Technology

    1980-04-01

    AD-A097 202 HARRY DIAMOND LABS ADELPHI MD F/S 17/1 THE ACOUSTO - OPTIC INTERACTION IN AN INFINITE SLAB OF ISOTROPIC -- ETC(U) APR 80 S D SCHARF...611101.91A0011 .A1.A1 HOL Project: A10935 1S. KEY WONS (Cf ft "W reweee eld. It neceseeM md Io.t.Itl by block nm er) Acousto - optics Diffraction Mathieu... Acousto - Optic Interaction for Bragg Angles ...................... 13 FIGURES 1. Incident wave is split by acoustic wave into discrete diffracted orders

  11. Analysis and Simulation of Hypervelocity Gouging Impacts

    DTIC Science & Technology

    2006-06-01

    Hypervelocity Gouging Test . . 8 -11 8.2.4 Further Results from the Comparison of CTH Simulations to the 1-D Penetration Theory . . . 8 - 13 8.2.5...more plasticity and gouge depth is generated and the temperature profile is correspondingly more significant. 8 - 13 Figure 8.14: Comparison of CTH...19a. NAME OF RESPONSIBLE PERSON 19b. TELEPHONE NUMBER (include area code) Standard Form 298 (Rev. 8 –98) Prescribed by ANSI Std. Z39.18 13 –06–2006

  12. Southern Great Basin Seimological data report for 1980 and preliminary data analysis

    SciTech Connect

    King, K.W.; Engdahl, E.R.

    1984-06-01

    Earthquake data for the calendar year 1980 are presented for earthquakes occurring within and adjacent to the southern Nevada seismograph network. Locations, magnitudes, and selected focal mechanisms for these events and events from prior years of network operation are presented and discussed in relation to the geologic framework of the region. The principal results are that (1) earthquakes concentrate in fault zones having a northeast orientation, (2) fault zones having a northwest orientation are quiescent or nearly so, and (3) no earthquakes have been detected closer than 12 km to the Yucca Mountain nuclear waste repository study area. 12 references, 13 figures.

  13. Basin-edge diapirism and updip salt flow in Zechstein of southern North Sea

    SciTech Connect

    Jenyon, M.K.

    1985-12-01

    Some unusual and interesting structural geometries have been recognized on seismic lines recorded in the United Kingdom sector the southern Permian basin of the North Sea. They seem to be the result of diapirism at the northern edge of the (Upper Permian) Zechstein salt basin, and involve the preservation of a 75 km (47 mi) long prism of a younger Mesozoic sequence replaced elsewhere by the widespread Jurassic/Cretaceous late Kimmerian unconformity. It is suggested that the diapiric features described are due to the movement of salt toward the basin edge having been dammed by a change in facies from basinal halite to shelf lithologies over a short distance. 13 figures.

  14. Implementation and Testing of Ice and Mud Source Functions in WAVEWATCH III (registered trademark)

    DTIC Science & Technology

    2013-04-19

    dispersed ice field, J. Fluid Mech., 202, 43-81. Mei, C.C. and Liu, K.-F., 1987: A Bingham - plastic model for a muddy seabed under long waves. J...Implementation and Testing of Ice and Mud Source Functions in WAVEWATCH III® W. Erick rogErs Mark D. orzEch Ocean Dynamics and Prediction Branch Oceanography...11 Figure 6. Final state of the second two-dimensional test case, as explained in the text. .............. 13 Figure 7. Comparison of WW3- predicted

  15. Piezocomposites for Active Surface Control

    DTIC Science & Technology

    1999-01-19

    section of 100 mm single layer SmartPanel 3 Figure 4. Preliminary design for 2-layer SmartPanel 3 Figure 5. Baseline SonoPanel configuration 4 Figure 6...baseline SonoPanel design 10 Figure 12. TVR of 100 x 100 mm baseline SonoPanel design 10 Figure 13. FFVS of 250 x 250 mm baseline SonoPanel design ...12 Figure 14. TVR of 250 x 250 mm baseline SonoPanel design 12 Figure15. 100 mm, 250 mm, and 750 mm SonoPanel transducers 13 Figure 16

  16. Method of making permanent magnets

    DOEpatents

    McCallum, R.W.; Dennis, K.W.; Lograsso, B.K.; Anderson, I.E.

    1993-09-07

    A method for making an isotropic permanent magnet comprises atomizing a melt of a rare earth-transition metal alloy (e.g., an Nd--Fe--B alloy enriched in Nd and B) under conditions to produce protectively coated, rapidly solidified, generally spherical alloy particles. Wherein a majority of the particles are produced/size classified within a given size fraction (e.g., 5 to 40 microns diameter) exhibiting optimum as-atomized magnetic properties and subjecting the particles to concurrent elevated temperature and elevated isotropic pressure for a time effective to yield a densified, magnetically isotropic magnet compact having enhanced magnetic properties and mechanical properties. 13 figures.

  17. High resolution track etch autoradiography

    DOEpatents

    Solares, G.; Zamenhof, R.G.

    1994-12-27

    A detector assembly is disclosed for use in obtaining alpha-track autoradiographs, the detector assembly including a substantially boron-free substrate; a detector layer deposited on the substantially boron-free substrate, the detector layer being capable of recording alpha particle tracks and exhibiting evidence of the alpha tracks in response to being exposed to an etchant, the detector layer being less than about 2 microns thick; and a protective layer deposited on the detector layer, the protective layer being resistant to the etchant and having a thickness of about 0.5 to 1 microns. 13 figures.

  18. Apparatus and methods for detecting chemical permeation

    DOEpatents

    Vo-Dinh, T.

    1994-12-27

    Apparatus and methods for detecting the permeation of hazardous or toxic chemicals through protective clothing are disclosed. The hazardous or toxic chemicals of interest do not possess the spectral characteristic of luminescence. The apparatus and methods utilize a spectrochemical modification technique to detect the luminescence quenching of an indicator compound which upon permeation of the chemical through the protective clothing, the indicator is exposed to the chemical, thus indicating chemical permeation. The invention also relates to the fabrication of protective clothing materials. 13 figures.

  19. Instrumented Experiments Aboard the Frigate WOLF. Wolf 2: Background Information Concerning the Transducers and Mounting Methods Used

    DTIC Science & Technology

    1992-08-01

    signaalbewerkingssysteem. Acc.,sion r rNTIS I Sr ,J. ,0..." .7.. ......... .......... I.-. . .- "," .. Ib TNO-report PML 292489093 Page 3 CONTENTS ...SUMMARY/SAMENVATTING 2 CONTENTS 3 1 INTRODUCTION 5 2 BLAST MEASUREMENTS 7 2.1 Pressure transducers 7 2.2 Mounting method of the pressure transducers 8 3... contents of this container are shown in Figure 13. Figure 13 Measurement set-up during the Wolf Phase II experiments (891057-19) TNO-report PML 292489093

  20. Transitioning Domain Analysis: An Industry Experience.

    DTIC Science & Technology

    1996-06-01

    Planning Activities 15 5.2 Contracting Resources 16 5.2.1 FODA Research Team 16 5.2.2 Supporting Organizations 18 5.3 Tool & Database Plan 18 5.3.1...References 6 Implementation 6.1 Analysis of Operator Services’ Requirements Process 21 6.2 Preliminary Planning for FODA Training by SEI 21...Groups in the Pilot Study 9 Figure 2: Flow of Communication and Needs Between the SEI, GSP and Operator Services 13 Figure 3: Nortel FODA

  1. Microelectronic superconducting crossover and coil

    DOEpatents

    Wellstood, F.C.; Kingston, J.J.; Clarke, J.

    1994-03-01

    A microelectronic component comprising a crossover is provided comprising a substrate, a first high T[sub c] superconductor thin film, a second insulating thin film comprising SrTiO[sub 3]; and a third high T[sub c] superconducting film which has strips which crossover one or more areas of the first superconductor film. An in situ method for depositing all three films on a substrate is provided which does not require annealing steps and which can be opened to the atmosphere between depositions. 13 figures.

  2. Effects of supply conditions on film thickness in lubricated Hertzian contacts

    NASA Technical Reports Server (NTRS)

    Dalmaz, G.; Godet, M.

    1980-01-01

    A generalization of the hydrodynamic expression for Hertzian contacts is described and various methods for calculating the thickness of the oil film winter steady-state, isothermal conditions are given. This is important for engineering applications such as gears and bearings because these results are closer to real operating conditions. Theories of lubrication are discussed, and the mathematics involved are presented using approximately 30 equations and 13 figures. For lubricated, linear, elliptical or point Hertzian contacts it is demonstrated how to calculate the thickness of the oil film at the center of the contact for steady-state isothermal conditions.

  3. Numerical Hopkinson Bar Analysis: Uni-Axial Stress and Planar Bar-Specimen Interface Conditions by Design

    DTIC Science & Technology

    2004-09-01

    3- D analysis, uni-axial stress, specimen design, planar bar-specimen interface, transmission tube 16. SECURITY CLASSIFICATION OF: 19a. NAME OF...direction; subscripts i = C, D , and E represent bar-center, specimen-edge, and bar-edge, respectively; superscripts j = 1 and 2; “1” = IB-S interface...S BD / D = 0.60 , S SH / D 1.00= , SD̂ = 0.60. .........13 Figure 11. Axial stress distribution on the surface of ceramic specimen at a different

  4. In Vitro Toxicity of Aluminum Nanoparticles in Rat Alveolar Macrophages

    DTIC Science & Technology

    2006-03-01

    This is due to aluminum’s effects on the gills, causing high ventilation rates, low oxygen blood tension, and overall gill damage that include an...there are many similarities between chromium (Cr), essential in glucose metabolism, and aluminum. Urine and plasma samples were taken from diabetic ...53 12. Figure 4-8: TNF-alpha Production….……………………………………………….54 .. 13. Figure 5-1: LD50 Dose Estimates and Low Exposure

  5. World economic outlook: a survey by the staff of the International Monetary Fund. [Monograph

    SciTech Connect

    Not Available

    1981-01-01

    This report extends the analysis of economic developments, policies, and prospects first presented in the May 1980 Outlook. the estimates and projections for various groups of industrial and developing countries are built up on a country-by-country basis, drawing on the International Monetary Fund's statistical resources and consultations. The global perspective now covers the People's Republic of China, nonmember European countries, and the Soviet Union. The report begins with a general survey, followed by chapters on industrial countries, oil-exporting developing countries, and non-oil developing countries. Key policy issues are identified as stagflation in industrial countries and global adjustment and financing. 14 figures, 50 tables. (DCK)

  6. Shore Ice Ride-Up and Pile-Up Features. Part 2. Alaska’s Beaufort Sea Coast--1983 and 1984,

    DTIC Science & Technology

    1984-09-01

    up to 3 m high on one edge of On the northwest side of Narwhal Island (Fig. the sandbag perimeter wall and in places had cas- A2) the sandy gravel...ice southwest end of Narwhal Island, VA-m-thick ice ride-up on the south side of Pole Island (position was thrust from the west approximately 30 m 0...ups were seen on several of the Narwhal Island. In addition, in several places ice barrier islands located northeast of Anderson Pt. 14 % . -_ Figure

  7. Distribution of radium and plutonium in human bone

    SciTech Connect

    Schlenker, R.A.

    1984-01-01

    This paper presents aspects of current and recent work on the distribution of radium and plutonium near the surfaces of human bone and applications of the data. Included are sections on methods, surface deposit thickness, radium distribution near the endosteal surface, the use of alpha spectrometry in conjunction with autoradiography, radium distribution in the mastoid, and factors affecting plutonium specific activity. Emphasis is placed on the alpha spectrometry technique because of its usefulness and its recent application to problems of local dosimetry. 19 references, 14 figures, 6 tables.

  8. Electrochemical thinning of silicon

    DOEpatents

    Medernach, J.W.

    1994-01-11

    Porous semiconducting material, e.g. silicon, is formed by electrochemical treatment of a specimen in hydrofluoric acid, using the specimen as anode. Before the treatment, the specimen can be masked. The porous material is then etched with a caustic solution or is oxidized, depending of the kind of structure desired, e.g. a thinned specimen, a specimen, a patterned thinned specimen, a specimen with insulated electrical conduits, and so on. Thinned silicon specimen can be subjected to tests, such as measurement of interstitial oxygen by Fourier transform infra-red spectroscopy (FTIR). 14 figures.

  9. Heartrate Response to a Single Submaximal Workload (Astrand’s Test) as an Estimate of Maximal Oxygen Uptake in British Servicemen

    DTIC Science & Technology

    1978-05-01

    Sercemen 23 6 FIGURE 1 7 Estimated max 102 and measured (treadmill) max 10ý - Athletes 25 8 Duplicated tests - estimated max 102 26 8 FIGURE 2 9 FIGURE 3 10...FIGURE 4 11 Estimation of max VO.rom cycle load or from subtmaxlmal VO2 28 12 PUMr 5 13 Fuxsi 6 14 FIGURE 7 15 "Diurnal Effects 32 16 FMIURE 8 17...Confirmatory criteria were increased respiratory quotient, and heartate near ago-predicted maximum . Lt study 6 blood samples were taken after each rui from

  10. Development of an Air Sampling and Analytical Method for 1,6-Hexamethylene Diisocyanate.

    DTIC Science & Technology

    1981-07-10

    naphthalenemethylamine (NMA) previously used by Levine et al. for collecting airborne diisocyanates in bubblers (7), and N -l- naphthyl - ethylenediamine (NED...1473 // 1 , __..... ... SECURITY CLASSIFICATI N OF’THIS PAGE 1I1’en Date En Now. INTRODUCTION During the summer of 1979 the principal investigator...configuration for analysis of NMA and HDI-NMA - - _V I O 14. Figur 2. HL hoaormso M n D-MAadTI sn cI (-$ . ! _ - 0 I ! 4 8 1 164 8 2 1 * 1 0 .. . . . . II

  11. Two-phase chromium-niobium alloys exhibiting improved mechanical properties at high temperatures

    DOEpatents

    Liu, C.T.; Takeyama, Masao.

    1994-02-01

    The specification discloses chromium-niobium alloys which exhibit improved mechanical properties at high temperatures in the range of 1250 C and improved room temperature ductility. The alloys contain a Cr[sub 2]Nb-rich intermetallic phase and a Cr-rich phase with an overall niobium concentration in the range of from about 5 to about 18 at. %. The high temperature strength is substantially greater than that of state of the art nickel-based superalloys for enhanced high temperature service. Further improvements in the properties of the compositions are obtained by alloying with rhenium and aluminum; and additional rare-earth and other elements. 14 figures.

  12. Enhanced photo-activated luminescence for screening polychlorobiphenyls (PCBs) and other related chlorinated compounds

    DOEpatents

    Tuan Vodinh.

    1993-12-21

    The presence of polychlorinated biphenyls and other chlorinated compounds in a sample is determined by treating the sample with a photo-activator and then exposing the treated sample to a UV light source. The UV light produces a photo-product complex, which is subsequently excited with UV light to cause luminescence of the complex. The luminescence is detected and characteristics of the luminescence spectra are used to determine the presence of chlorinated compounds and also the quantity of the chlorine in the compounds. 14 figures.

  13. Mathematical Fluid Dynamics of Store and Stage Separation

    DTIC Science & Technology

    2005-05-01

    used to characterize the interaction of the waves with the microstructure and the results are validated against experiment. 14 . SUBJECT TERMS boundary...problem (Problem P 1) ..... 14 Figure 12 Computational schlieren snapshots of instantaneous cavity flow fields with and w ithout jet control...governed by 14 SC71193.RFRFTV r RoCKWELL J SCIENTIFIC L[G] - (7a) 2 =0, (7b) G(ooz, 0) < oc• (7c) where 6(x) signifies the delta function of x. Further

  14. Hybrid Architectures for Evolutionary Computing Algorithms

    DTIC Science & Technology

    2008-01-01

    STATEMENT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. PA# WPAFB 08-0064 13. SUPPLEMENTARY NOTES 14 . ABSTRACT This report documents the...operator (in Xilinx StateCadtool) …….. 14 Figure 6. Partial code fragment of the declone operator, hand coded from state Diagram...Histogram of number of words added by exhaustive search for the runs of Figure 12 ………………………………………………………... 27 Figure 14 . Performance comparison of

  15. The Investigation into Hydraulic Gear Pump Efficiencies in the First Few Hours of the Pump’s Lives and a Comparative Study of Accelerated Life Tests Methods on Hydraulic Fluid Power Gear Pumps. Part III.

    DTIC Science & Technology

    1980-07-31

    8217 Milwaukee School of Engineering 1025 N. MilwaukeeSt. _Milwaukee1 _Wisconsin 53201 ______ ICOMTT40LLING OFFICE NAML ANt- .UorRLSb 12 RIEPORT DATF US Army...Other test standards used in this effort are referenced in report parts I and II. -1- 80 9 11 O14, Figure No. 3.3.6 Number of Pump Test Specimens Broken...Z0(0-- .0-*0- 5a--- m- CD 0.E C CCM,0 A MCD 0. A L"J 0 A 3.7 Observations 3.7.1 Using either of the two methods for determining displacement produces

  16. Monoclonal antibodies for the separate detection of halodeoxyuridines and method for their use

    DOEpatents

    Vanderlaan, M.; Watkins, B.E.; Stanker, L.H.

    1991-10-01

    Monoclonal antibodies are described which have specific affinities for halogenated nucleoside analogs and are preferentially selective for one particular halogen. Such antibodies, when incorporated into immunochemical reagents, may be used to identify and independently quantify the cell division character of more than one population or subpopulation in flow cytometric measurements. Independent assessment of division activity in cell sub-populations facilitates selection of appropriate time and dose for administration of anti-proliferative agents. The hybridomas which secrete halogen selective antibodies and the method of making them are described. 14 figures.

  17. The Shock and Vibration Bulletin: Proceedings on the Symposium on shock and Vibration (52nd) Held in New Orleans, Louisiana on 26-28 October 1981. Part 1. Welcome, Keynote Address, Invited Papers, Rotor Dynamics and Machinery Vibration

    DTIC Science & Technology

    1982-05-01

    experimental manikins to learn more about the 24 Figure 14 Figure ISr 25 Figure 10 IAX Vehicle X4%ay EtI*cM: TheWfl Eflet: " Emaecioecs (IemptUAImp...drifts in the tunnels. In other caes, we actually run Figure 25 illustrates a high explosive simulation technique cables up to the top of the mountain...OCK TARGET ~ 8TRUCTUft Fig. 25 - High explosive simulation technique (HEST) Kg I Figure 26 I 31 CENTRAL REFEREN4CE RACR ANdFO CHARGE- CONdSTRUCTED FROM

  18. Description of the MHS Health Level 7 Chemistry Laboratory for Public Health Surveillance

    DTIC Science & Technology

    2012-09-01

    3 Data Origination and Flow Process...Methods used to determine timeframe in HL7 data…………………………………….…….14 Figure 1: HL7 Laboratory data flow process…………………………………………………………………….7 Figure...laboratory testing. Document Title 5 5 EpiData Center Department HL7 Microbiology Technical Document Data Origination and Flow Process Figure

  19. Identification and Characterization of Post-Translational Modifications on EAF1 and EAF2 in Prostate Cancer

    DTIC Science & Technology

    2014-06-01

    16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON USAMRMC a . REPORT U b ...upper blot) and goat anti-GAPDH (lower blot). 14 Figure 4 A B Figure 4: Loss of either hmg-1.2 or pha-4 in eaf-1 knockout C. elegans results...Figure 6 A B GFP-HMGB1 + RFP GFP-HMGB1 + RFP-U19 Merged GFP RFP Hoechst GFP-ce-hmg1.2 + Myc GFP-ce-hmg1.2 + Myc-ce-eaf1 Merged GFP Hoechst GFP

  20. Aerospace Mechanisms Symposium (22nd) Held at Hampton, Virginia on 4-6 May 1988.

    DTIC Science & Technology

    1988-05-06

    base with redundant reading heads. The Mobile Transporter also has to detect which bay it is on at any time. Various methods of encoding truss... extend from the actuator. As the wax cools and solidifies, it contracts, allowing the rod to be pushed back into the actuator. These commercial...and 2b. This actuator will extend 7.5 cm against a resisting force of 120 N (27 Ibs) when heated from 35 0 C to 40 0 C. 14 Figure 2a: HOP Ac~utcr

  1. A Progress Report on Undergraduate Software Engineering Education

    DTIC Science & Technology

    1994-05-01

    Figures Figure 2.1. Locations of Undergraduate Programs Surveyed 3 Figure 3.1. Locations of Software Engineering Graduate Programs 14 Figure 3.2 Growth of...and Senior Years 21 Figure 3.4 CMU Combined Electrical and Computer Engineering Curriculum 22 Table of Tables Table 3.1. Graduate Programs in...Software Engineering 13 Table 3.2. Graduate Programs in Computer Science with a Software Engineering Option 13 ii CMU/SEI-94-TR-11 A Progress Report on

  2. Microelectronic superconducting device with multi-layer contact

    DOEpatents

    Wellstood, F.C.; Kingston, J.J.; Clarke, J.

    1993-10-26

    A microelectronic component comprising a crossover is provided comprising a substrate, a first high T[sub c] superconductor thin film, a second insulating thin film comprising SrTiO[sub 3] ; and a third high T[sub c] superconducting film which has strips which crossover one or more areas of the first superconductor film. An in situ method for depositing all three films on a substrate is provided which does not require annealing steps. The photolithographic process is used to separately pattern the high T[sub c] superconductor thin films. 14 figures.

  3. Steam Reforming of Methyl Fuel - Phase I

    DTIC Science & Technology

    1977-06-30

    1./CHR[ON ) M A-14 ....... FIGURE 11. REKRF5ThA OF~j ~ U MAIN PRODUCT MOLE FRACTIONS 1 C(S),2 COP3 C02 9 4 CH4,5 H2o6 H20 1.0 .8 *z __ _ _-_-_ __" o...c~.0 A- RU FIGU Rh "TR O 0F -ME7THY5LJ MRIN PRODUCT MOLE FRACTIONS IC(S) 2 COP3 C0294 CH4 .5 H2 G H20 Ld .4 .2- .00 (ST[RM/CRBfON)M A- 17 FICURE 14

  4. Evaluation of Suppression of Hydroprocessed Renewable Jet (HRJ) Fuel Fires with Aqueous Film Forming Foam (AFFF)

    DTIC Science & Technology

    2011-07-01

    Capture of a Tallow Fire ....................................................15 Figure 14. Foam Layer Advancing from Lower Left to Upper Right...the conventional JP-8 fuel (MIL-DTL-83133F) that is currently used by the Air Force and two bio-oil derived HRJ fuels: Camelina and Tallow . The HRJ...Conventional Jet Fuel (JP-8) Shell Oil Products/ Mobil > 100 °F (> 38 °C) Camelina HRJ UOP LLC > 100 °F (> 38 °C) Tallow HRJ UOP LLC > 100 °F (> 38 °C

  5. Nevada Nuclear Waste Storage Investigations environmental area characterization report, compiled July 1982

    SciTech Connect

    1984-07-01

    The Environmental Area Characterization Report describes the southwestern corner of the Nevada Test Site, Nye County, Nevada, a potential location for a geologic repository for high-level radioactive waste. The characterization summarizes reports supplied by Sandia National Laboratories, which cover the following topics: atmosphere, radiation background, hydrosphere, biosphere, energy and mineral resources, socioeconomics, and cultural resources. This report is one of a series of documents sponsored by the US Department of Energy, Nevada Nuclear Waste Storage Investigations Project. 43 references, 15 figures, 20 tables.

  6. Effects of Positive Acceleration on Corneal Stability in Photorefractive Keratectomy (PRK) Subjects

    DTIC Science & Technology

    2005-06-01

    Corneal Topography …………………..………………………………... 17 Visual Acuity…………………………………………………………..... 18 Discussion...Change As A Function of +Gz………………………. 15 Figure 12: Autokeratometry Changes As A Function Of +Gz……………………. 16 Figure 13: Corneal Topography ...both eyes within 10 minutes. Corneal topography data was collected using the EyeSys Vista™ HANDHELD CORNEAL TOPOGRAPHER (HCT) (Figure 8

  7. Role of the 5HT3 Receptor in Alcohol Drinking and Aggression Using A Transgenic Mouse Model

    DTIC Science & Technology

    2005-09-01

    F(1,35) = 33.85, P < 0.0005] and N5 generations [F(1,35) = 6.33, P < 0.017]. Interactions of background and transgene presence were found for N1 [F... interaction was found for the N5 generation as well [F(2,51) = 4.55, P < 0.15]. Figure 2. Contextual conditioning is influenced by 5-HT3 receptor...2,51) = 164.56, P < 0.0005] and transgene presence [F(1,51) = 51.66, P < 0.0005] were found, as was an interaction between background and transgene

  8. Cr-W-V bainitic/ferritic steel with improved strength and toughness and method of making

    DOEpatents

    Klueh, R.L.; Maziasz, P.J.

    1994-03-08

    This work describes a high strength, high toughness bainitic/ferritic steel alloy comprising about 2.75% to 4.0% chromium, about 2.0% to 3.5% tungsten, about 0.10% to 0.30% vanadium, and about 0.1% to 0.15% carbon with the balance iron, wherein the percentages are by total weight of the composition, wherein the alloy having been heated to an austenitizing temperature and then cooled at a rate sufficient to produce carbide-free acicular bainite. 15 figures.

  9. Gas flow means for improving efficiency of exhaust hoods

    DOEpatents

    Gadgil, A.J.

    1994-01-11

    Apparatus is described for inhibiting the flow of contaminants in an exhaust enclosure toward an individual located adjacent an opening into the exhaust enclosure by providing a gas flow toward a source of contaminants from a position in front of an individual to urge said contaminants away from the individual toward a gas exit port. The apparatus comprises a gas manifold which may be worn by a person as a vest. The manifold has a series of gas outlets on a front face thereof facing away from the individual and toward the contaminants to thereby provide a flow of gas from the front of the individual toward the contaminants. 15 figures.

  10. Commercial scale demonstration enhanced oil recovery by micellar-polymer flood. Monthly progress report, March 1985

    SciTech Connect

    Mueller, L.M.

    1985-03-01

    This report describes work conducted on the Maraflood oil recovery process, M-1 Project, throughout the month of March 1985. Information is presented under two Work Breakdown Structure (WBS) elements: WBS 2300 - performance monitoring; and WBS 2400 - economic monitoring. Performance monitoring reporting includes discussions of the 2.5-acre and 5.0-acre pattern oil cut performance for March 1985. Economic monitoring discusses the abandonment of one producing well in the 2.5-acre pattern area of the M-1 Project. 15 figures.

  11. Research Using In Vivo Simulation of Meta-Organizational Shared Decision-making (SDM). Task 4: Modeling of Communication and Decision Functions within a Shared Decision-making (SDM) Framework

    DTIC Science & Technology

    2011-12-01

    coordonnée, ce qui peut être particulièrement utile lorsque les organisations ou les groupes planifient et développent des tâches et des scénarios à...the main concepts and constructs used throughout the research process . DRDC CSS CR 2011-33 15 Figure 1: Overview of research strategy...impacts, media involvement, and political processes ; 2) Uncertainty – which includes sub-elements such as novelty of situation, anticipation and planning

  12. Flash Platform Examination

    DTIC Science & Technology

    2011-03-01

    15 Figure 14: The Myna Audio Editor is a powerful web based tool to “remix music tracks and audio clips. Apply sound effects and record your...displays “real time ship traffic and the positions of moored vessels in the world’s largest ports powered by the vesseltracker.com AIS network”[117... powered by LCDS ES2. The application features wizard-style guided navigation for self service customers, real-time document collaboration, and a live chat

  13. Apparatus for storing high magnetic fields having reduced mechanical forces and reduced magnetic pollution

    DOEpatents

    Prueitt, M.L.; Mueller, F.M.; Smith, J.L.

    1991-04-09

    The present invention identifies several configurations of conducting elements capable of storing extremely high magnetic fields for the purpose of energy storage or for other uses, wherein forces experienced by the conducting elements and the magnetic field pollution produced at locations away from the configuration are both significantly reduced over those which are present as a result of the generation of such high fields by currently proposed techniques. It is anticipated that the use of superconducting materials will both permit the attainment of such high fields and further permit such fields to be generated with vastly improved efficiency. 15 figures.

  14. Shockwave Propagation in Nonequilibrium Air Plasma

    DTIC Science & Technology

    2006-07-01

    V cm-1), the observed B3Πg – A3Σu+ intensity jumps by at least 20% compared to the steady state in 2 μs. This requires a rate of change of the...S.E.Ponomareva, V.M.Shibkov, High Temp. 29, 468 (1990) 5. Y.Z. Ionikh, N. V . Chernysheva, A . V . Meshchanov, A . P. Yalin and R.B. Miles, Phys. Lett. A 259...Cathode Anode 15 Figure 2a -15 -10 -5 0 m V 1.51.00.50.0 mS 20 15 10 5 m

  15. Large Scale Integrated Circuits for Military Applications.

    DTIC Science & Technology

    1977-05-01

    4 -» E§o, •»- "O irt » z •— C C CO o s- E E 1- 10 0 8 •"•» 4 - O...Institutional Considerations iii v 1 4 9 16 17 19 19 29 35 39 42 48 53 59 59 65 68 71 75 75 78 LJ vii &a m u : »1 s...rr""- I u I! I > a ii ,11 la. lb. lc. 2. 3. 4 . 5. 6. 7, 8a. 8b. 9. 10. 11. 12. 13. 1%. 15. FIGURES Price/Gate

  16. Modelling and assessment of advanced processes for integrated environmental control of coal-fired power plants. Technical progress report

    SciTech Connect

    Barrett, J.G.; Bloyd, C.N.; McMichael, F.C.; Rubin, E.S.

    1984-07-01

    The key objective of this research is the development of a computer based model for the assessment of integrated environmental control (IEC) systems for conventional and advanced coal fired power plant designs. Efforts during the period April 1-June 30, 1984 focused on, (1) testing of a preliminary integrated model linking pre-combustion and post-combustion control options for conventional plants; (2) documentation of the analytical models of existing control technology options; (3) development and preliminary testing of a second model design for the propagation and analysis of uncertainty; and (4) development of new analytical models needed for IEC assessments. Activities and accomplishments in each of these areas are described. 4 references, 13 figures, 4 tables.

  17. Method for imaging with low frequency electromagnetic fields

    DOEpatents

    Lee, K.H.; Xie, G.Q.

    1994-12-13

    A method is described for imaging with low frequency electromagnetic fields, and for interpreting the electromagnetic data using ray tomography, in order to determine the earth conductivity with high accuracy and resolution. The imaging method includes the steps of placing one or more transmitters, at various positions in a plurality of transmitter holes, and placing a plurality of receivers in a plurality of receiver holes. The transmitters generate electromagnetic signals which diffuse through a medium, such as earth, toward the receivers. The measured diffusion field data H is then transformed into wavefield data U. The travel times corresponding to the wavefield data U, are then obtained, by charting the wavefield data U, using a different regularization parameter [alpha] for each transform. The desired property of the medium, such as conductivity, is then derived from the velocity, which in turn is constructed from the wavefield data U using ray tomography. 13 figures.

  18. Striped bass, temperature, and eutrophication: a speculative hypothesis for environmental risk

    SciTech Connect

    Coutant, C.C.

    1982-01-01

    The paradoxical record of striped bass distribution and abundance, including population declines in coastal waters and variable success of freshwater introductions, is analyzed for consistency with a thermal niche-dissolved oxygen-squeeze hypothesis. A commonality among diverse field and laboratory observations supports a genetic-based thermal niche for the species that changes to lower temperatures as fish age. This shift can cause local conditions, especially warm surface strata and deoxygenated deep water, to be incompatible with the success of large fish. Crowding due to temperature preferences and avoidance of low oxygen concentrations can lead to pathological symptoms and over fishing, which may contribute to population declines. Through a mixture of evidence and conjecture, the thermal niche-dissolved oxygen hypothesis is proposed as a unified perspective of the habitat requirements of the species that can aid in its study and management. 141 references, 13 figures.

  19. Characterization of two types of crystalloids in pleomorphic adenomas of minor salivary glands. A light-microscopic, electron-microscopic, and histochemical study.

    PubMed Central

    Campbell, W. G.; Priest, R. E.; Weathers, D. R.

    1985-01-01

    Crystalloids have been previously described in salivary gland tumors. In order to ascertain the incidence of these structures, the authors reviewed a series of 294 minor salivary gland tumors. One hundred thirty pleomorphic adenomas were identified, and 6 of these contained crystalloids. No crystalloids were found in other benign or malignant salivary gland tumors. These six file cases and a recent seventh case containing crystalloids were studied by light and electron microscopy and with histochemistry. Two types of crystalloids were found. One case contained previously described tyrosine-rich crystalloids, and the other six contained crystalloids composed of radially arranged collagen fibers. Both types of crystalloids are further characterized and discussed. Images Figure 1-3 Figure 4-6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 PMID:2982270

  20. SPLENOPORTAGRAPHY IN PORTAL HYPERTENSION—Its Value in Selecting the Operative Procedure of Choice

    PubMed Central

    Mikkelsen, William P.; Pattison, Arthur C.

    1957-01-01

    Splenoportagraphy has become an almost indispensable adjunct to the surgical management of portal hypertension. In many instances it will provide the basis for the selection of the operative procedure. Certain instances of intrahepatic portal hypertension due to cirrhosis that might better be managed by splenorenal shunt rather than by the generally preferred method of direct end-to-side portacaval shunt may be determined by this procedure. The procedure finds its greatest application in the accurate delineation of the three major types of extrahepatic portal hypertension, each of which demands a different surgical approach. ImagesFigure 1.Figure 2.Figure 3.Figure 4.Figure 5.Figure 6.Figure 7.Figure 8.Figure 9.Figure 10.Figure 11.Figure 12.Figure 13.Figure 14. PMID:13413692

  1. Neovascularization and tumor growth in the rabbit brain. A model for experimental studies of angiogenesis and the blood-brain barrier.

    PubMed Central

    Zagzag, D.; Brem, S.; Robert, F.

    1988-01-01

    A model for the study of tumor angiogenesis within the rabbit brain is presented. Implantation of the VX2 carcinoma provides a reproducible tumor accompanied by angiogenesis. The authors report the sequential growth, histology, tumor neovascularization, and vascular permeability of this tumor following its intracerebral implantation. Tumor angiogenesis correlates with the rapid and logarithmic intracerebral tumor growth. The proliferation of blood vessels in the tumor and the organization of tumor cells around tumor vessels are described. Breakdown of the blood-brain barrier (detected by Evans blue leakage) starts in the early stages of tumor development and becomes prominent as the tumor vasculature and size increase. This model is useful for experimental studies of angiogenesis. Images Figure 2 Figure 3 Figure 6 Figure 4 Figure 5 Figure 7 Figure 8 Figure 10 Figure 12 Figure 13 Figure 15 PMID:2451889

  2. Benefits of explosive cutting for nuclear-facility applications

    SciTech Connect

    Hazelton, R.F.; Lundgren, R.A.; Allen, R.P.

    1981-06-01

    The study discussed in this report was a cost/benefit analysis to determine: (1) whether explosive cutting is cost effective in comparison with alternative metal sectioning methods and (2) whether explosive cutting would reduce radiation exposure or provide other benefits. Two separate approaches were pursued. The first was to qualitatively assess cutting methods and factors involved in typical sectioning cases and then compare the results for the cutting methods. The second was to prepare estimates of work schedules and potential radiation exposures for candidate sectioning methods for two hypothetical, but typical, sectioning tasks. The analysis shows that explosive cutting would be cost effective and would also reduce radiation exposure when used for typical nuclear facility sectioning tasks. These results indicate that explosive cutting should be one of the principal cutting methods considered whenever steel or similar metal structures or equipment in a nuclear facility are to be sectioned for repair or decommissioning. 13 figures, 7 tables. (DLC)

  3. Photobioreactors: models for interaction of light intensity, reactor design, and algal physiology

    SciTech Connect

    Frohlich, B.T.; Webster, I.A.; Ataai, M.M.; Shuler, M.L.

    1983-01-01

    A generalized structured, nonsegregated model for algal growth has been developed. Cell components were active biomass, reserves, chlorophyll and associated pigments, and photosynthate. The computer model can predict the behavior of the system in batch and continuous culture. The model can be used to determine the optimal combination of independent variables (dilution rate (D), incident light intensity (I/sub 0/), concentration of the first-limiting inorganic nutrient (S/sub 0/), and vessel geometry (L)) to maximize the economic productivity of a continuous culture system. An effectiveness factor approach has been developed that allows the rapid estimation of the combination of D, I/sub 0/, S/sub 0/, and L resulting in light-limited growth. This approach is novel in that it is applied to the reactor as a whole rather than a single catalyst pellet. 39 references, 13 figures.

  4. Thread gauge for tapered threads

    DOEpatents

    Brewster, A.L.

    1994-01-11

    The thread gauge permits the user to determine the pitch diameter of tapered threads at the intersection of the pitch cone and the end face of the object being measured. A pair of opposed anvils having lines of threads which match the configuration and taper of the threads on the part being measured are brought into meshing engagement with the threads on opposite sides of the part. The anvils are located linearly into their proper positions by stop fingers on the anvils that are brought into abutting engagement with the end face of the part. This places predetermined reference points of the pitch cone of the thread anvils in registration with corresponding points on the end face of the part being measured, resulting in an accurate determination of the pitch diameter at that location. The thread anvils can be arranged for measuring either internal or external threads. 13 figures.

  5. Neutron and gamma dose and spectra measurements on the Little Boy replica

    SciTech Connect

    Hoots, S.; Wadsworth, D.

    1984-06-01

    The radiation-measurement team of the Weapons Engineering Division at Lawrence Livermore National Laboratory (LLNL) measured neutron and gamma dose and spectra on the Little Boy replica at Los Alamos National Laboratory (LANL) in April 1983. This assembly is a replica of the gun-type atomic bomb exploded over Hiroshima in 1945. These measurements support the National Academy of Sciences Program to reassess the radiation doses due to atomic bomb explosions in Japan. Specifically, the following types of information were important: neutron spectra as a function of geometry, gamma to neutron dose ratios out to 1.5 km, and neutron attenuation in the atmosphere. We measured neutron and gamma dose/fission from close-in to a kilometer out, and neutron and gamma spectra at 90 and 30/sup 0/ close-in. This paper describes these measurements and the results. 12 references, 13 figures, 5 tables.

  6. Analysis of gravity anomaly over coral-reef oil field: Wilfred Pool, Sullivan County, Indiana

    SciTech Connect

    Dana, S.W.

    1980-03-01

    To compare the measured and theoretical gravity anomaly of a typical coral-reef oil field, data were collected from the wilfred Pool, Sullivan County, Indiana. Densities of available core samples from the field were determined and the anomaly was calculated, taking into account the lateral and vertical variation of density and the geologic structure known from core studies and drilling-log records of lithologic types penetrated by the wells. Comparison of the theoretical and actual anomalies indicated a rough correspondence except for several sharp negative anomalies on the flanks of the measured gravity anomaly. Further studies indicated that the negative anomalies are possibly due to fluvial erosion that produced, on the surface of the youngest Pennsylvanian sediments, channels which were later filled with glacial till of lower density than the sediments. 13 figures.

  7. Radiological dose assessments of atolls in the Northern Marshall Islands

    SciTech Connect

    Robison, W.L.

    1983-11-01

    Methods and models used to estimate the radiation doses to a returning population of the atolls in the Marshall Islands are presented. In this environment natural processes have acted on source-term radionuclides for nearly 30 years. The data bases developed for the models, and the results of the radiological dose analyses at the various atolls are described. The major radionuclides in order of their contribution to the total estimated doses were /sup 137/Cs, /sup 90/Sr, /sup 239/ /sup 240/Pu, /sup 241/Am, and /sup 60/Co. Exposure pathways in order of their contribution to the estimated doses were: terrestrial food chain, external ..gamma.., marine food chain, inhalation, and cistern water and ground water. 56 references, 13 figures, 16 tables.

  8. Fabrication process for a gradient index x-ray lens

    DOEpatents

    Bionta, R.M.; Makowiecki, D.M.; Skulina, K.M.

    1995-01-17

    A process is disclosed for fabricating high efficiency x-ray lenses that operate in the 0.5-4.0 keV region suitable for use in biological imaging, surface science, and x-ray lithography of integrated circuits. The gradient index x-ray optics fabrication process broadly involves co-sputtering multi-layers of film on a wire, followed by slicing and mounting on block, and then ion beam thinning to a thickness determined by periodic testing for efficiency. The process enables the fabrication of transmissive gradient index x-ray optics for the 0.5-4.0 keV energy range. This process allows the fabrication of optical elements for the next generation of imaging and x-ray lithography instruments in the soft x-ray region. 13 figures.

  9. Portable centrifugal analyzer for the determination of rapid reaction kinetics

    SciTech Connect

    Bostick, W.D.; Bauer, M.L.; McCracken, R.; Mrochek, J.E.

    1980-02-01

    A portable centrifugal analyzer prototype is capable of rapidly initiating reactions and monitoring 17 optical channels as they rotate past a stationary photodetector. An advanced rotor drive permits transfer of discretely loaded sample and reagent into a cuvette within 60 ms. Various rotor designs have been employed to ensure effieicnt mixing concurrent with solution transfer, thus permitting absorbance or luminescence measurements to be made almost immediately after solution contract. Dye-dillution studies have been used to investigate transfer and mixing efficiencies. Rotor designs with parallel access for sample and reagent into the cuvette were found to promote efficient mixing during liquid transfer. The hypochlorite-luminol chemiluminescent reaction served to demonstrate the utility of the system for performing rapid kinetic analyses. Appropriate adjustment of reaction conditions allows first-order reaction half-lives as short as 0.04 s to be measured. 13 figures, 3 tables.

  10. Preburn versus postburn mineralogical and geochemical characteristics of overburden and coal at the Hanna, Wyoming underground coal gasification site

    SciTech Connect

    Oliver, R.L.; Youngberg, A.D.

    1983-12-01

    Hundreds of mineralogic and geochemical tests were done under US Department of Energy contracts on core samples taken from the Hanna underground coal gasification site. These tests included x-ray diffraction studies of minerals in coal ash, overburden rocks, and heat-altered rocks; x-ray fluorescence analyses of oxides in coal ash and heat-altered rocks; semi-quantitative spectrographic analyses of elements in coal, overburden, and heat-altered rocks; chemical analyses of elements and compounds in coal, overburden, and heat-altered rocks and ASTM proximate and ultimate analyses of coal and heat-altered coal. These data sets were grouped, averaged, and analyzed to provide preburn and postburn mineralogic and geochemical characteristics of rock units at the site. Where possible, the changes in characteristics from the preburn to the postburn state are related to underground coal gasification processes. 11 references, 13 figures, 8 tables.

  11. Cerebral scintigraphy--the phoenix rises again.

    PubMed Central

    Shepstone, B. J.

    1988-01-01

    This paper reviews the development of cerebral scintigraphy from its early days of planar imaging with simple technetium-99m labelled compounds to the recent revival of the technique in the form of positron-emission and single-photon emission tomography. A short explanation of instrumentation and radiopharmaceuticals is given as a prelude to a description of both techniques in normal and pathological situations. Particular emphasis is placed on the more readily-available single-photon emission-tomographic techniques using labelled amines in the functional investigation of disorders not readily diagnosed by computed tomography. Images Figure 2(a) Figure 3 Figure 4 Figure 5 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 PMID:3047720

  12. Teaching electron diffraction and imaging of macromolecules.

    PubMed Central

    Chiu, W; Schmid, M F; Prasad, B V

    1993-01-01

    Electron microscopic analysis can be used to determine the three-dimensional structures of macromolecules at resolutions ranging between 3 and 30 A. It differs from nuclear magnetic resonance spectroscopy or x-ray crystallography in that it allows an object's Coulomb potential functions to be determined directly from images and can be used to study relatively complex macromolecular assemblies in a crystalline or noncrystalline state. Electron imaging already has provided valuable structural information about various biological systems, including membrane proteins, protein-nucleic acid complexes, contractile and motile protein assemblies, viruses, and transport complexes for ions or macromolecules. This article, organized as a series of lectures, presents the biophysical principles of three-dimensional analysis of objects possessing different symmetries. Images FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 17 FIGURE 18 PMID:8324196

  13. Morphology of the spleen and lymph nodes in fatal visceral leishmaniasis.

    PubMed Central

    Veress, B; Omer, A; Satir, A A; El Hassan, A M

    1977-01-01

    Histological appearances of the spleen and lymph nodes were analysed in twenty fatal cases of human visceral leishmaniasis from Sudan. Marked atrophy of the splenic white pulp was associated with necrosis and fibrosis of thymus-dependent area, accumulation of parasite-containing histiocytes and plasma cell hyperplasia. Depletion of small lymphocytes in the paracortical areas of the lymph nodes was accomplained by proliferation of plasma cells and histiocytes in the paracortex. Depletion of small lymphocytes in thymus-dependent regions of lymph nodes and spleen is viewed as arising from immune suppression associated with antigen overloading or other factors, which may impair those aspects of lymphocyte-macrophage cooperation that are presumably necessary to kill the invading parasites. Images Figures 1-4 Figures 5-6 PMID:590992

  14. Application of asphalt emulsion seals to uranium mill tailings

    SciTech Connect

    Hartley, J.N.; Koehmstedt, P.L.; Esterl, D.J.; Freeman, H.D.; Clark, R.L.

    1980-11-01

    Studies of asphalt emulsion sealants have demonstrated that the sealants are effective in containing radon and other potentially hazardous material within uranium tailings. The laboratory and field studies have further demonstrated that radon exhalation from uranium tailings piles can be reduced by greater than 99% to less than background levels. Field tests at the tailings pile in Grand Junction, Colorado confirmed that an 8-cm admix seal containing 22 wt % asphalt could be effectively applied with a cold-mix paver. Other techniques were successfully tested, including a soil stabilizer and a hot, rubberized asphalt seal that was applied with a distributor truck. After the seals were applied and conpacted, overburden was applied over the seal to protect the seal from ultraviolet degradation. 14 figures.

  15. Status of the development of 2-(5-cyanotetrazolato) pentaamminecobalt(III) perchlorate for DDT devices

    SciTech Connect

    Lieberman, M.L.; Fronabarger, J.W.

    1980-01-01

    The inorganic explosive 2-(5-cyanotetrazolato) pentaamminecobalt(III) perchlorate (CP) was synthesized by conventional coordination chemistry preparative methods. Its structure has been established via /sup 15/N NMR spectroscopy and x-ray diffraction techniques. Impurities have been identified and characterized. Procedures for qualification of the powder for detonator use have been established. Investigations of thermal properties are underway and no corrosion or compatibility problems have been determined under normal detonator environments. The physics of deflagration-to-detonation transition (DDT) of CP is being addressed. Studies are in progress to determine the shock characteristics of unreacted material, detonation parameters, equation of state of the reaction products, and characteristics of the transition to detonation. Engineering considerations have included measurements relating CP particle size, compaction behavior, spark sensitivity, shock sensitivity thermal ignition sensitivity, growth-to-detonation in device hardware, and output. 14 figures, 3 tables.

  16. Theoretical implications on ISABELLE physics

    SciTech Connect

    Wang, L L.C.

    1980-01-01

    A brief historical review of the development of understanding of the weak interaction and its final unification with electromagnetic theory is given first. Then the production cross sections of W/sup + -/ and Z/sup 0/ in hadronic scatterings are estimated; CVC, scaling, Drell-Yan model, structure functions and perturbative QCD, sigma/sub w/, sigma/sub z/, and production rate are aspects considered. Next, the detection of the Z/sup 0/ and W/sup + -/ in leptonic decay and hadronic decay is discussed, along with some detail features of the Drell-Yan model. Then an estimate of the onia production is given, and the Higgs boson and the technicolor pseudoscalar production are considered. In conclusion, anticipated work in these areas at ISABELLE is summarized. 48 references, 14 figures, 2 tables. (RWR)

  17. Wildlife distribution and abundance on the Utah oil shale tracts 1975-1984

    SciTech Connect

    Grant, C.V.

    1986-07-01

    Distribution and abundance of 215 amphibians, reptiles, birds, and mammals were monitored for 10 years on Utah's Oil Shale Tracts using line transects, mist netting, and live trapping. Wildlife monitoring was conducted in four major vegetation types and during all seasons to establish a quantitative baseline for use in impact identification during oil shale mining. Habitat preferences were established for many species in cold desert vegetation of two types of desert shrub, and juniper and riparian woodlands. Seasonal, annual, and habitat distribution of each class demonstrated a variety of adaptive responses to environmental variables. The most important environmental variables, that is, those factors resulting in a predictable change in wildlife populations, were, in descending order: weather, food resource, shelter, and competition. 31 references, 14 figures, 10 tables.

  18. In-Situ Tuff Water Migration/Heater Experiment: posttest thermal analysis

    SciTech Connect

    Eaton, R.R.; Johnstone, J.K.; Nunziato, J.W.; Korbin, C.M.

    1983-10-01

    This report describes posttest laboratory experiments and thermal computations for the In-Situ Tuff Water Migration/Heater Experiment that was conducted in Grouse Canyon Welded Tuff in G-Tunnel, Nevada Test Site. Posttest laboratory experiments were designed to determine the accuracy of the temperatures measured by the rockwall thermocouples during the in-situ test. The posttest laboratory experiments showed that the measured in-situ rockwall temperatures were 10 to 20{sup 0}C higher than the true rockwall temperatures. The posttest computational results, obtained with the thermal conduction code COYOTE, were compared with the experimentally obtained data and with calculated pretest results. Daily heater output power fluctuations (+-4%) caused by input power line variations and the sensitivity of temperature to heater output power required care in selecting the average heater output power values used in the code. The posttest calculated results compare reasonably well with the experimental data. 10 references, 14 figures, 5 tables.

  19. Final Report of the Lower Extremity Assessment Program (LEAP 99-2). Volume 2

    DTIC Science & Technology

    2000-08-01

    2 tB/3 1B 1A 0 MB 131310 BFR/OS BMetB Boot Type Figure 7: Injury Comparisons PMN 4 2A USS/ MedEng DBFR/ MedEng PATS 2 OBS/OB DGB/OS OSanda/ 1A 1...0 Sanda/ CS CS/OS SB/OS SER/OS SER/ MedEng BS/ MedEng Boot Type 14 Figure 8: Injury Comparisons Combat Boot 4 3 213 *M-14 2A *PMN MTS 2 18 1A n=5 n=l 1...AD NO. TECOM PROJECT NO. 8-EI-495-BPF001 REPORT NO. ATC-8199 (VOLUME II) USAISR INSTITUTE REPORT LEAP 99- 2 VOLUME II FINAL REPORT OF THE

  20. Radiological survey of Johnston Atoll. Dates of survey: April-August 1980. Revision 1

    SciTech Connect

    Jaffe, R.J.; Tipton, W.J.

    1982-04-01

    A radiological survey was conducted over all land areas of Johnston Atoll between April and August 1980. The survey was performed to locate and quantify residual surface transuranic (i.e., plutonium and americium) contamination resulting from three THOR missile aborts which occurred during that portion of the 1962 atmospheric nuclear testing series conducted by the United States from Johnston Island. A high purity germanium planar detector was utilized to enhance the detection sensitivity for the 59.5 keV gamma ray from /sup 241/Am. Results are reported as equivalent surface concentration in units of nCi/m/sup 2/. Conversion factors are also included for several other assumed source distributions. Soil samples were obtained to determine plutonium-to-americium ratios. 7 references, 14 figures, 1 table.

  1. Violent tornado climatography, 1880-1982

    SciTech Connect

    Grazulis, T.P.

    1984-05-01

    All known information sources, ranging from newspaper reports to the University of Chicago (DAPPL) and National Oceanic and Atmospheric Administration (NOAA/NSSFC) data lists, were utilized to produce a self-consistent compilation and description of violent tornado occurrences in the contiguous United States for the years 1880 through 1982. The 969 F-scale 4 and 5 tornadoes comprise the most complete and rational data base available for studies elated to violent tornado risk assessment; the data provide improved bases for licensing decisions and development of standards in safety at nuclear facility sites. Reconciliation of the DAPPL and NSSFC data lists for violent tornadoes has been achieved. Analysis of the data shows geographical and temporal variability of tornado occurrences; suggestions are given to help account for nonuniform distributions, and other suggestions are made for needed future research. 32 references, 14 figures, 8 tables.

  2. ELECTRON MICROSCOPIC STUDIES OF RENAL DISEASE

    PubMed Central

    Latta, Harrison

    1960-01-01

    The nephrotic syndrome, glomerulonephritis, disseminated lupus erythematosus and the Fanconi syndrome show characteristic changes with electron microscopy. Experimental studies of animals were carried out to determine the significance of such changes by observing reactions that occur under carefully controlled conditions. A lesion with collagen deposition that was found in the centrolobular region of glomeruli sheds new light on the function of this region. This evidence must be considered in developing an understanding of how the production of urine is controlled. Fluid-filled compartments and various bodies associated with the ultrastructure of tubule cells can be produced under conditions which suggest that these structures play a role in tubular resorption. ImagesFigure 1, 2.Figure 3.Figure 4, 5.Figure 6, 7.Figure 8, 9.Figure 10.Figure 11, 12.Figure 13, 14.Figure 15, 16.Figure 17. PMID:13759386

  3. Noise control at fossil fuel power plants: an industrywide assessment of costs and benefits. Final report

    SciTech Connect

    Hoover, R.M.

    1983-12-01

    This report presents the results of a study on the costs and perceived benefits of noise control measures currently installed at fossil power plants. Information for this study was sought from the entire fossil power plant industry in this country through a questionnaire survey and through discussions with utility personnel. A total of 84 power companies responded with information on plants. In addition, five power plants with extensive noise control measures were selected for detailed study. For these plants, case histories were prepared following plant visits and discussions with utility personnel regarding the specific noise control measures. Based on these case histories and the results of the questionnaire survey, noise control costs and perceived benefits are presented for major power plant equipment categories including draft fans, boiler feed pumps, turbine-generator systems, valves, and transformers. 12 references, 14 figures, 7 tables.

  4. Middle Cenozoic depositional, tectonic, and sea level history of southern San Joaquin basin, California

    SciTech Connect

    Decelles, P.G.

    1988-11-01

    As a prolific producer of hydrocarbons, the San Joaquin basin in south-central California has been the subject of geological research since the late nineteenth century. Much of this research has focused on the subsurface Eocene to lower Miocene succession because of its attractive reservoir potential. Although seismic and well-log data are available in profuse quantities, the complex sedimentary architecture of the basin fill, the application of local and inconsistent stratigraphic nomenclature, and the inherent limitations of subsurface data have led to much confusion concerning the middle Cenozoic history of the basin. This paper presents a sedimentological analysis of the depositional systems in the Eocene to lower Miocene strata of the San Emigdio and Tehachapi Mountains. The various depositional systems are considered within the contexts of encompassing depositional sequences to reconstruct the middle Cenozoic depositional, tectonic, and sea level history of the southern San Joaquin basin. 14 figures, 1 table.

  5. Laboratory-scale evaluations of alternative plutonium precipitation methods

    SciTech Connect

    Martella, L.L.; Saba, M.T.; Campbell, G.K.

    1984-02-08

    Plutonium(III), (IV), and (VI) carbonate; plutonium(III) fluoride; plutonium(III) and (IV) oxalate; and plutonium(IV) and (VI) hydroxide precipitation methods were evaluated for conversion of plutonium nitrate anion-exchange eluate to a solid, and compared with the current plutonium peroxide precipitation method used at Rocky Flats. Plutonium(III) and (IV) oxalate, plutonium(III) fluoride, and plutonium(IV) hydroxide precipitations were the most effective of the alternative conversion methods tested because of the larger particle-size formation, faster filtration rates, and the low plutonium loss to the filtrate. These were found to be as efficient as, and in some cases more efficient than, the peroxide method. 18 references, 14 figures, 3 tables.

  6. Zuni sequence in Williston basin - evidence for Mesozoic paleotectonism

    SciTech Connect

    Shurr, G.W.; Anna, L.O.; Peterson, J.A.

    1989-01-01

    The Zuni sequence in the Williston basin is a largescale lithogenetic package bounded by interregional unconformities. Within the sequence, three major subdivisions are separated by unconformities or marker beds and correspond with chronostratigraphic units: (1) Middle and Upper Jurassic, (2) Lower Cretaceous, and (3) Upper Cretaceous and Paleocene. The basin has clear expression in the Jurassic subdivision, poor expression in the Lower Cretaceous, and good expression in the Upper Cretaceous. A series of seven marginal paleotectonic elements surround the basin center on the west, south, and east in the US. Five more marginal elements have been described in Canada. Occurrences of oil in the Jurassic and Lower Cretaceous and of natural gas in the Upper Cretaceous are broadly related to the pattern of marginal paleotectonic elements. 14 figures, 1 table.

  7. Preparation and composition of superconducting copper oxides based on Ga-O layers

    DOEpatents

    Dabrowski, B.; Vaughey, J.T.; Poeppelmeier, K.R.

    1994-12-20

    A high temperature superconducting material with the general formula GaSr[sub 2]Ln[sub 1[minus]x]M[sub x]Cu[sub 2]O[sub 7[+-]w] wherein Ln is selected from the group consisting of La, Ce, Pt, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb and Y and M is selected from the group consisting of C and Sr, 0.2[<=]x[<=]0.4 and w is a small fraction of one. A method of preparing this high temperature superconducting material is provided which includes heating and cooling a mixture to produce a crystalline material which is subsequently fired, ground and annealed at high pressure and temperature in oxygen to establish superconductivity. 14 figures.

  8. Structural changes induced by energetic heavy-ion bombardment in BaFe/sub 12/O/sub 19/: HREM investigation for low irradiation doses

    SciTech Connect

    Hervieu, M.; Groult, D.; Raveau, B.; Fuchs, G.

    1986-04-01

    Monocrystalline and polycrystalline samples of hexaferrite BaFe/sub 12/O/sub 19/ irradiated with argon and krypton ion beams of 44 and 35 MeV per nucleon, respectively, have been investigated by HREM for doses close to a x 10/sub 13/ and 2 x 10/sub 12/ ions.cm..sqrt../sub 1/. Electron microscopy examinations of the samples placed in the low energy range (0 less than or equal to E < 0.6 GeV for Ar and 0 less than or equal to E < 0.9 GeV for Kr) show several characteristic, morphologic, and crystallographic features involving numerous fractures, important bendings of the crystals, and extensive disorder leading to the loss of periodicity in the c direction. Typical induced defects have been observed and are believed to be associated with displacement cascades created by the primary ejected ions. 14 references, 14 figures.

  9. Separation of alkali, alkaline earth and rare earth cations by liquid membranes containing macrocyclic carriers. Fourth progress report, 1 November 1981-31 July 1982

    SciTech Connect

    Christensen, J J; Izatt, R M

    1982-07-31

    The H/sub 2/O-CHCl/sub 3/-H/sub 2/O liquid membrane system was characterized with respect to the effect on cation (K/sup +/) transport rate of salt concentration and anion type. A bulk liquid membrane cell was used. A mathematical model for cation flux is being developed for several cations, several macrocycles, and mixtures of two or three cations. Eu/sup 3 +/ was not transported by 18-crown-6, but its reduced from Eu/sup 2 +/ was. Cation transport properties of calixarenes are also being investigated. Emulsion membrane systems were studied as a way of increasing the cation transport. Pb/sup 2 +/ was found to be transported by dicyclohexano-18-crown-6 through the liquid membrane. Transport rates of metal cation nitrates were measured in a water-toluene-water emulsion membrane system. 14 figures, 7 tables. (DLC)

  10. Apparatus and method for servicing an elongated suspended pump motor in an electric power plant with limited access

    DOEpatents

    Chavez, R.V.; Ekeroth, D.E.; Johnson, F.T.; Matusz, J.M.

    1994-04-26

    Elongated coolant pumps suspended under steam generators within containment in a power plant with limited access space, are removed and replaced by an elongated maintenance cart with an elongated opening along one side in which the motor is received. Rollers support the cart for conveying the elongated motor in an upright position out from under the steam generator and onto an elevator. The elevator is lowered to transfer support of the cart and motor through trunnions to saddles straddling the elevator for rotation of the cart to a generally horizontal position. The elevator then raises the horizontally disposed cart carrying the motor to a higher floor where it is rolled off the elevator and out through the auxiliary equipment hatch. 14 figures.

  11. Automated interferometric alignment system for paraboloidal mirrors

    DOEpatents

    Maxey, L.C.

    1993-09-28

    A method is described for a systematic method of interpreting interference fringes obtained by using a corner cube retroreflector as an alignment aid when aligning a paraboloid to a spherical wavefront. This is applicable to any general case where such alignment is required, but is specifically applicable in the case of aligning an autocollimating test using a diverging beam wavefront. In addition, the method provides information which can be systematically interpreted such that independent information about pitch, yaw and focus errors can be obtained. Thus, the system lends itself readily to automation. Finally, although the method is developed specifically for paraboloids, it can be seen to be applicable to a variety of other aspheric optics when applied in combination with a wavefront corrector that produces a wavefront which, when reflected from the correctly aligned aspheric surface will produce a collimated wavefront like that obtained from the paraboloid when it is correctly aligned to a spherical wavefront. 14 figures.

  12. Engineering evaluation of plant oils as diesel fuel. Final report. Vol. I

    SciTech Connect

    Engler, C.R.; Johnson, L.A.; Lepori, W.A.; Yarbrough, C.M.

    1983-09-13

    This project includes evaluations of cottonseed oils and sunflower oil ethyl esters in both direct injection and precombustion chamber design diesel engines. It is one part of a major research program at Texas A and M University to study the technical feasibility of using plant oils or animal fats as alternative diesel fuels. Goals for the overall program are to define physical and chemical characteristics and optimum processing methods required for high quality alternative diesel fuels from plant or animal oils and to investigate effects of engine design on alternative fuel performance. This report describes work done under the current contract which includes evaluations of cottonseed oils and sunflower oil interesterified with ethanol as alternative diesel fuels. 15 figures, 18 tables.

  13. Investigation of Boundary-Layer Transition on Smooth Hemispherical Bodies

    DTIC Science & Technology

    2010-11-17

    was 0° . The sounding rocket propelling the test item had an M6 "Honest John" first stage motor, with an M5 "Nike’’ upper stage. 10 0 TC1 5 c TC2...Unclassifierl Unclassified 10 0 TC1 5 0 TC2 0 TC3 1::. TC4 v TC5 0 TC6 I> TC7 * TC8 + TC9 • TC10 -5 X TC11 I * TC12 - 10 0 5 10 15 Figure 2...5 of 18 American Institute of Aeronautics and Astronautics U nclassilierl nclassified 101 0 TC1 5 0 TC2 ¢ TC3 /;. TC4 v TC5 0 TC6 t> TC7

  14. Phase-sensitive flow cytometer

    DOEpatents

    Steinkamp, J.A.

    1993-12-14

    A phase-sensitive flow cytometer (FCM) provides additional FCM capability to use the fluorescence lifetime of one or more fluorochromes bound to single cells to provide additional information regarding the cells. The resulting fluorescence emission can be resolved into individual fluorescence signals if two fluorochromes are present or can be converted directly to a decay lifetime from a single fluorochrome. The excitation light for the fluorochromes is modulated to produce an amplitude modulated fluorescence pulse as the fluorochrome is excited in the FCM. The modulation signal also forms a reference signal that is phase-shifted a selected amount for subsequent mixing with the output modulated fluorescence intensity signal in phase-sensitive detection circuitry. The output from the phase-sensitive circuitry is then an individual resolved fluorochrome signal or a single fluorochrome decay lifetime, depending on the applied phase shifts. 15 figures.

  15. Chemical effect of entrained particles in coal conversion streams. Sixth quarterly technical progress report, November 1, 1982-January 31, 1983

    SciTech Connect

    Stinespring, C.; Yousefian, V.; Gruninger, J.; Annen, K.; Frankel, D.; Stewart, G.

    1983-01-01

    A major objective of the US Department of Energy is to increase coal utilization through the development of combustion stream cleanup technologies. Many of the existing cleanup devices as well as advanced concepts rely on heterogeneous processes (i.e., gas-solid interactions) to achieve efficient stream removal. Examples of such devices include particle injection and granular bed filters for alkali removal, limestone injection for SO/sub x/ removal in fluid bed combustors, dry injection for SO/sub x/removal in entrained combustion, and trace metal adsorption and removal on fly ash. Recent studies indicate that the successful use of turbines in combined cycle processes may depend on understanding the interaction between the gas phase alkali and particles in the combustion stream to substantially reduce turbine corrosion. This report documents progress in efforts to model the heterogeneous chemistry of coal combustion streams as well as laboratory studies to obtain critical input data for the report. 5 references, 15 figures.

  16. Chemical and physical characterization of phosphorus smokes for inhalation exposure and toxicology studies. Final report. [Red phosphorus containing butyl rubber; white phosphorus impregnated in felt

    SciTech Connect

    Ramsey, R.S.; Moneyhun, J.H.; Holmberg, R.W.

    1985-04-01

    The chemical and physical properties of the aerosols produced from the combustion of red phosphorus containing butyl rubber (RPBR) and white phosphorus impregnated in felt (WPF) have been examined. The aerosols were produced at a uniform concentration by extruding softened raw material and burning the emerging filament or by igniting fragments of the formulations in a convective air flow. Aeorsol particle sizes were found to be within the respirable range, varying from 0.4 to 1.0 micrometers depending upon generation conditions and aerosol age at collection. Chemically, both RPBR and WPF aerosols were found to be very similar, composed primarily of water and phosphoric acids. Organic compounds and inorganic gases were detected only at trace levels. 11 references, 15 figures, 11 tables.

  17. Major salt beds of the Palo Duro and Dalhart Basins, Texas

    SciTech Connect

    Not Available

    1983-12-01

    Major salt beds are defined as salt intervals at least 75 feet thick that contain no interbeds greater than 10 feet thick and include no more than 15 percent non-salt interbeds. Maps based on the interpretation of geophysical logs from hundreds of oil and gas exploration wells reveal seven major salt beds in the Palo Duro Basin and one major salt bed in the Dalhart Basin. The most extensive major salt beds are in the central and northern Palo Duro Basin, in the Upper San Andres Formation and the Lower San Andres Formation Units 4 and 5. Of these, the major salt bed within the Lower San Andres Formation Unit 4 is the most widespread and generally the thickest. 7 references, 15 figures, 2 tables.

  18. Handbook on surficial uranium deposits. Chapter 3. World distribution relative to climate and physical setting

    SciTech Connect

    Carlisle, D

    1983-01-01

    This chapter discusses regional controls which affect the world distribution of surficial chemogenic uranium deposits. The most important of these are (1) climate, (2) geomorphology, including physiographic and climatic stability, and (3) provenance, i.e., the weathering terrain from which uranium and associated substances are derived. The three economically important environments are the calcrete environment, simple evaporative environments and paludal environments. Of these three categories, the calcrete uranium environment is probably the most uniquely constrained in terms of regional climate, geomorphic setting, provenance (vanadium as well as uranium) and especially the need for long term stability of both climate and physiography. Purely evaporative deposits, though subject to some of the same kinds of constraints, can also reflect local circumstances and a wider range of climates, physiographic settings, and source terrains. The third category encompassing bogs, marshes and organic-rich playas can form under an even wider range of climates and settings provided only that organic materials accumulate in abundance and are contacted by uranium-bearing waters. For all of these reasons and also because of the great economic importance of the calcrete environment as well as its relative novelty and complexity the discussion in this chapter is focused on calcrete, dolocrete and gypcrete uranium deposits. Objective data are reviewed first follwed by inferences and suggestions. 13 figures.

  19. Overview of the oxidation and scavenging characteristics of April rains (OSCAR) experiment

    SciTech Connect

    Easter, R.C.; Dana, M.T.; Thorp, J.M.; Busness, K.M.; Hales, J.M.; Raynor, G.S.; Benkovitz, C.M.; Tanner, R.L.; Shannon, J.D.

    1984-04-01

    The OSCAR (Oxidation and Scavenging Characteristics of April Rains) field experiment was conducted in April, 1981, as part of the MAP3S/RAINE program. The OSCAR study was designed to provide detailed characterizations of the physicochemical and dynamical features of selected cyclonic storm systems as they traversed the eastern U.S. Major experiment components included sequential precipitation chemistry measurements, aircraft measurements both in cloud and in clear air in storm inflow regions, surface-level air chemistry measurements, and supporting meteorological measurements. The precipitation chemisty network consisted of an intermediate-density network with 37 sampling sites covering the region from southern Ontario to Tennessee and from Illinois to New Hampshire, and a high-density network with 47 sampling sites located in a 100 by 100 km area in northeast Indiana. A total of four storm events were studied during the experiment. The report describes the design and operational aspects for the high-density and intermediate-density components of the experiment, and the composition of the integrated OSCAR data set which has been developed. A synoptic meteorological description of the four storm events studied during OSCAR is also provided. 17 references, 13 figures, 8 tables.

  20. Experimental modeling of role of gravity and lateral shortening in Zagros mountain belt

    SciTech Connect

    Koyi, H.

    1988-11-01

    Dynamically scaled analogs of the geologic structures of the Zagros mountain belt are used to argue that different parts of the Zagros Mountains of Iran record different combinations of the effects of a gravity-driven overturn and a southwest-northeast lateral shortening superimposed on the Zagros overturn. Partially scaled material models have been used to simulate the Zagros geodynamics, which involve layer-parallel compression of a 6 to 7 km-thick Phanerozoic carbonate cover containing a pattern of preshortening diapirs. The folds in the Zagros form rapidly (1.5 mm/yr in a 20 to 30 km-wide zone), reactivate some of the preshortening diapirs, and generate new synshortening listric diapirs. A third set of postshortening diapirs rises from the Hormuz decollement behind the fold-thrust front. Model buckle folds superimposed on diapirs or pillows tend to avoid and curve around preshortening diapirs, which flatten in the synclines. Model profiles show that lateral shortening induces residual salt at depth to flow toward and rise through the anticlinal cores as synshortening or postshortening diapirs. The author suggests that any salt pillows in currently diapir-free zones of the Zagros fold-thrust belt may surface as diapirs through the anticlines in the future. 13 figures, 4 tables.

  1. Focus control system for stretched-membrane mirror module

    DOEpatents

    Butler, B.L.; Beninga, K.J.

    1991-05-21

    A focus control system dynamically sets and controls the focal length of a reflective membrane supported between a perimeter frame. A rear membrane is also supported between the perimeter frame rearward and spaced apart from a back side of the reflective membrane. The space between the membranes defines a plenum space into which a mass of gas at a first pressure is inserted. The pressure differential between the first pressure and an external pressure, such as the atmospheric pressure, causes the reflective membrane to assume a first curvature relative to a reference plane associated with the perimeter frame. This curvature defines the focal length of the reflective membrane. The focal length is dynamically controlled by changing the volume of the plenum space, thereby changing the first pressure. The system can be used to change or maintain the pressure differential and hence the front membrane curvature. The plenum volume is changed by pushing or pulling on a central section of the rear membrane using a suitable actuator. Sensing means continuously sense the location of the reflective membrane relative to the reference plane. This sensed position is compared to a reference position, and a resulting error signal, comprising the difference between the sensed position and reference position, drives the actuator in a direction to minimize the difference. A vent value compensates for temperature changes or leaks in the closed volume by allowing the pressure differential to be adjusted as required to center the working range of the actuator about the desired focal length. 13 figures.

  2. Carbon-bonded carbon fiber insulation for radioisotope space power systems

    SciTech Connect

    Wei, G.C.; Robbins, J.M.

    1985-05-01

    A carbon-bonded carbon fiber (CBCF) insulation developed for a radioisotope heat source is made from chopped rayon fiber about 10 ..mu..m in diameter and 250 ..mu..m long, which is carbonized and bonded with phenolic resin particles. The CBCF is an excellent lightweight insulating material with a nominal density of 0.2 Mg/m/sup 3/ and a thermal conductivity of 0.24 W/(m-K) in vacuum at 2000/sup 0/C. Several attributes that make CBCF particularly suitable for the heat source application have been identified. These include light weight, low thermal conductivity, chemical compatibility, and high-temperature capabilities. The mechanical strength of CBCF insulation is satisfactory for the application. The basic fabrication technique was refined to eliminate undesirable large pores and cracks often present in materials fabricated by earlier techniques. Also, processing was scaled up to increase the fabrication rate by a factor of 10. The specific properties of the CBCF were tailored by adjusting material and processing variables to obtain the desired results. 22 references, 13 figures, 4 tables.

  3. Configurational testing of electron beam ionization for coal fly ash precipitators. Quarterly report No. 2, November 5, 1983-February 4, 1984

    SciTech Connect

    Davis, R.H.

    1984-01-01

    The energy-geometry matching condition reported in Quarterly Report No. 1 has been incorporated in the design of a Mark II precharger and construction is underway. By matching the energy and geometry, monopolar charging is assured by providing a charging zone outside the ionization zone. Particle charges greater than the Pauthenier limit were observed using a bi-electrode geometry. Either or both free electron charging or space-charge enhancement of the electric field may be responsible for the increase in charge above the theoretical limit for the average electric field. A separate experiment on free electron charging proceeded during this quarter and the progress is reported. To date the exhaustive experiments on resistance modification by simple electron beam irradiation have not provided evidence to support practical utilization. However, preliminary experiments do suggest that the presence of small amounts of SO/sub 2/ and the subsequent conversion of SO/sub 2/ by electron beam treatment may conductively coat high resistivity fly ash particles with a resultant reduction in resistivity. The status of the laboratory precipitator test system is reported along with the preparations for tests of the new Mark II precharger module. During this quarter a patent disclosure on a device to enhance radiation dose was submitted to the US Department of Energy. 13 figures.

  4. Glucagon-, glicentin-, and pancreatic polypeptide-like immunoreativities in rectal carcinoids and related colorectal cells.

    PubMed Central

    Fiocca, R.; Capella, C.; Buffa, R.; Fontana, R.; Solcia, E.; Hage, E.; Chance, R. E.; Moody, A. J.

    1980-01-01

    Three nonargentaffin rectal carcinoids have been investigated immunohistochemically. In one case most tumor cells reacted with antiglucagon sera as well as with antiglicentin, antibovine pancreatic polypeptide (BPP), and antihuman pancreatic polypeptide (HPP) sera; they were identified ultrastructurally as L cells. Another case showed glucagon-, glicentin-, and BPP-immunoreactive cells but lacked HPP immunoreactivity. In the third case glucagon- and glicentin-immunoreactive cells were well represented, while PP immunoreactivities were scarce. Parallel investigations of human rectal and sigmoid mucosa showed numerous cells reacting with glucagon, glicentin, and BPP antisera, most of which lacked HPP immunoreactivity. Cells reacting with glucagon and glicentin antisera, while lacking PP immunoreactivities, were also found. Thus, both tumor and nontumor cells produce glucagonlike immunoreactive (GLI) peptides--one of which may be glicentin or a related molecule--as well as PP-related sequences, although differing histochemically and ultrastructurally from glucagon or PP cells of the human pancreas. It is concluded that nonargentaffin rectal carcinoids are histogenetically linked to nonargentaffin endocrine cells of the human rectum. Images p[92]-a Figures 1-3 Figure 4 Figure 5 PMID:7395969

  5. Chemically induced bidirectional differentiation of embryonal carcinoma cells in vitro.

    PubMed Central

    Speers, W. C.; Birdwell, C. R.; Dixon, F. J.

    1979-01-01

    N,N-dimethylacetamide, hexamethylene bisacetamide, and Polybrene induced rapid and extensive differentiation in vitro in an otherwise slowly differentiating subline of embryonal carcinoma cells. The type of differentiated cell induced was dependent on the spatial organization of the stem cells during drug treatment. In monalayer culture "epithelial" cells were produced exclusively. However, treatment of aggregated suspension cultures yielded predominantly "fibroblast-like" cells. The undifferentiated embryonal carcinoma cells and the two differentiated cell types were morphologically distinct when examined by light microscopy, scanning electron microscopy, and transmission electron microscopy; and they had differences in cell surface antigens. Both differential cell types produced large amounts of fibronectin, whereas the embryonal carcinoma cells produced only minimal amounts. This system provides a convenient way to induce relatively synchronous differentiation of embryonal carcinoma cells into specific differentiated cell types. Images Figure 5 Figure 6 Figure 1 Figure 2 Figure 3 Figure 4 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 PMID:507191

  6. Modeling of strongly heat-driven flow in partially saturated fractured porous media

    SciTech Connect

    Pruess, K.; Tsang, Y.W.; Wang, J.S.Y.

    1984-10-01

    We have performed modeling studies on the simultaneous transport of heat, liquid water, vapor, and air in partially saturated fractured porous media, with particular emphasis on strongly heat-driven flow. The presence of fractures makes the transport problem very complex, both in terms of flow geometry and physics. The numerical simulator used for our flow calculations takes into account most of the physical effects which are important in multi-phase fluid and heat flow. It has provisions to handle the extreme non-linearities which arise in phase transitions, component disappearances, and capillary discontinuities at fracture faces. We model a region around an infinite linear string of nuclear waste canisters, taking into account both the discrete fractures and the porous matrix. From an analysis of the results obtained with explicit fractures, we develop equivalent continuum models which can reproduce the temperature, saturation, and pressure variation, and gas and liquid flow rates of the discrete fracture-porous matrix calculations. The equivalent continuum approach makes use of a generalized relative permeability concept to take into account for fracture effects. This results in a substantial simplification of the flow problem which makes larger scale modeling of complicated unsaturated fractured porous systems feasible. Potential applications for regional scale simulations and limitations of the continuum approach are discussed. 27 references, 13 figures, 2 tables.

  7. Inhaled particles in human disease and animal models: use of electron beam instrumentation.

    PubMed Central

    Brody, A R

    1984-01-01

    The mineral pneumoconioses (lung disease caused by inhalation of inorganic dust) have been an important disease entity for centuries. In the last several decades, the electron microscope has been used to elucidate the distribution and identification of inhaled minerals, to aid in establishing etiologic factors, and less commonly, to determine the basic biologic mechanisms through which inhaled minerals cause lung disease. In this section, I review the instrumentation and tissue preparation currently used to address some modern problems in particle-induced lung disease. For example, human pneumoconioses of undetermined etiology can be clarified by electron microscopy and X-ray energy spectrometry. In addition, the initial deposition patterns of asbestos and silica are demonstrated in animal models, and the contributions of electron microscopy in establishing the initial lesions of asbestosis are described. Images FIGURE 1. FIGURE 2. FIGURE 3. FIGURE 4. FIGURE 5. FIGURE 6. FIGURE 7. FIGURE 8. FIGURE 9. FIGURE 9. FIGURE 10. FIGURE 11. FIGURE 12. FIGURE 13. FIGURE 14. PMID:6090114

  8. Subterranean stress engineering experiments

    SciTech Connect

    Campbell, J.R.; Colgate, S.A.; Wheat, B.M.

    1980-01-01

    The state of stress in a subterranean rock mass has classically been assumed to be constant at best. In soil with a high clay content, preconsolidation and drainage methods can lead to more stable foundation material, but methods for engineering the stresses in large masses of rock are not well known. This paper shows the results from an experiment designed to alter the in situ rock stress field in an oil shale mine. This was done by hydrofracturing the rock by use of a packed-well injection system and then propping the crack open with a thixotropic gel, which slowly hardened to the consistency of cement. Successive hydrofracture and high-pressure grouting resulted in an overstressed region. Well-head injection pressures, surface tilts, injection rates, and subterranean strains were measured and recorded on floppy disk by a Z-80 microprocessor. The results were then transmitted to the large computer system at the Los Alamos Scientific Laboratory (LASL). To put the data in a more useful form, computer-generated movies of the tilts and strains were made by use of computer graphics developed at LASL. The purpose of this paper is to present results from the Single Large Instrumented Test conducted in the Colony Oil Shale Mine near Rifle, Colorado. 13 figures.

  9. Measurements of uranium mill tailings consolidation characteristics

    SciTech Connect

    Fayer, M J

    1985-02-01

    A series of experiments were conducted on uranium mill tailings from the tailings pile in Grand Junction, Colorado, to determine their consolidation characteristics. Three materials (sand, sand/slimes mix, slimes) were loaded under saturated conditions to determine their saturated consolidated behavior. During a separate experiment, samples of the slimes material were kept under a constant load while the pore pressure was increased to determine the partially saturated consolidation behavior. Results of the saturated tests compared well with published data. Sand consolidated the least, while slimes consolidated the most. As each material consolidated, the measured hydraulic conductivity decreased in a linear fashion with respect to the void ratio. Partially saturated experiments with the slimes indicated that there was little consolidation as the pore pressure was increased progressively above 7 kPa. The small amount of consolidation that did occur was only a fraction of the amount of saturated consolidation. Preliminary measurements between pore pressures of 0 and 7 kPa indicated that measurable consolidation could occur in this range of pore pressure, but only if there was no load. 13 references, 13 figures.

  10. Immunoreactivity of anti-streptococcal monoclonal antibodies to human heart valves. Evidence for multiple cross-reactive epitopes.

    PubMed Central

    Gulizia, J. M.; Cunningham, M. W.; McManus, B. M.

    1991-01-01

    Association of group A streptococci with acute rheumatic fever and valvular heart disease is well established; however the basis of valve injury remains unclear. In this study, anti-streptococcal monoclonal antibodies (MAbs) cross-reactive with myocardium were reacted with sections from 22 rheumatic valves, nine normal, five endocarditic, one 'floppy,' and one Marfan valve. In immunohistochemical studies, MAb reactivity was observed with cardiac myocytes, smooth muscle cells, cell surface and cytoplasm of endothelial cells lining valves, and valvular interstitial cells. Endothelial basement membrane and elastin fibrils reacted with the MAbs, whereas collagen was unreactive. Similar reactivity was seen with sera from acute rheumatic fever patients. The anti-streptococcal MAbs reacted with intravalvular myosin and vimentin in Western blots, and purified elastin competitively inhibited the binding of the anti-streptococcal MAbs to whole group A streptococci. The data show that human heart valves have numerous sites of immunoreactivity with anti-streptococcal MAbs and acute rheumatic fever sera of potential importance in the pathogenesis of rheumatic valvular injury. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 PMID:1704188

  11. Kinetics and advanced digester design for anaerobic digestion of water hyacinth and primary sludge

    SciTech Connect

    Chynoweth, D.P.; Dolenc, D.A.; Ghosh, S.; Henry, M.P.; Jerger, D.E.; Srivastava, V.J.

    1982-01-01

    A research program centered around a facility located at Walt Disney World (WDW) is in progress to evaluate the use of water hyacinth (WH) for secondary and tertiary wastewater treatment, to optimize growth of WH under these conditions, and to convert the resultant primary sludge (PS) and WH to methane via anaerobic digestion. This article describes the status of the biogasification component of this program, which includes baseline and advanced digestion experiments with individual feeds and blends and the design of an experimental test unit (ETU) to be installed at WDW. Experiments with several blends demonstrated that methane yields can be predicted from the fractional content and methane yield of each component. The process was found to adhere to the Monod kinetic model for microbial growth, and associated kinetic parameters were developed for various feed combinations. A novel upflow digester is achieving significantly higher conversion than a stirred-tank digester. Of several pretreatment techniques used, only alkaline treatment resulted in increased biodegradability. A larger scale (4.5 m/sup 3/) experimental test unit is being designed for installation at WDW in 1982. 13 figures, 4 tables.

  12. A hydrophobic hole transporting system to improve moisture stability of perovskite solar cells (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Xiao, Lixin

    2016-09-01

    Non-ion additive hole-transporting material (HTM) of hydrophobic oligothiophene derivative named DR3TBDTT and triphenylamine derivative of N,N'-di(3-methylphenyl)-N,N-diphenyl-4,4-diaminobiphenyl (TPD) were used for the organic-inorganic hybrid perovskite solar cells. The power conversion efficiency (PCE) was comparable to the device using Li-TFSI doped spiro-MeOTAD. Moreover, the PCE decreases by only 10% after approximately 1000 h without encapsulation, which suggests an alternative method to improve the stability of perovskite solar cells[1-3 ]. Figure 1. Schematic illustration of the energy diagram of the device without lithium salts REFERENCES [1] Zheng, L.; Ma, Y.; Chu, S.; Wang, S.; Qu, B.; Xiao, L.; Chen, Z.;Gong, Q.; Wu, Z.; Hou, X. Nanoscale 6, 8171-8176 (2014). [2] Zheng Lingling, Chung Yao-Hsien, Ma Yingzhuang, Zhang Lipei, Xiao Lixin, Chen Zhijian, Wang Shufeng, Qu Bo and Gong Qihuang, Chem. Commun. 50, 11196-11199 (2014). [3] Ma Yingzhuang, Chung Yao-Hsien, Zheng Lingling, Zhang Danfei, Yu Xiao, Xiao Lixin, Chen Zhijian, Wang Shufeng, Qu Bo, Gong Qihuang, and Zou Dechun, ACS Appl. Mater. Interfaces 7 (12), 6406-6411 (2015)

  13. HHF35, a muscle actin-specific monoclonal antibody. II. Reactivity in normal, reactive, and neoplastic human tissues.

    PubMed Central

    Tsukada, T.; McNutt, M. A.; Ross, R.; Gown, A. M.

    1987-01-01

    Monoclonal antibody HHF35 has previously been characterized biochemically as recognizing isotypes of actin (alpha and gamma) which are specific to muscle cells. In this study, the authors have investigated the normal and pathologic tissue distribution of HHF35-positive cells using the avidin-biotin immunoperoxidase method on methacarn-fixed, paraffin-embedded sections of human tissue. In addition to muscle tissues (smooth, skeletal, and cardiac) the antibody localizes to myoepithelium, as well as most of the capsular cells of several parenchymal organs, including liver, kidney, and spleen, with extension of the latter cells into the splenic trabeculaes. In pathologic tissues, the antibody localizes to cells, identified by some investigators as "myofibroblasts," in the stroma of certain tumors, within hyperplastic fibrous tissue responses ("fibromatoses") such as Dupuytren's contracture, and within fibrotic lung tissue. HHF35 also localizes to cells that proliferate within the intima in lesions of atherosclerosis and to a unique population of reactive mesothelial and submesothelial cells. Among tumors, it is positive only on leiomyomas, leiomyosarcomas, and rhabdomyosarcomas, and negative on all nonmuscle sarcomas. This antibody thus shows great potential utility as a diagnostic reagent in various pathologic conditions, most especially in the diagnosis of tumors of muscle origin. Images Figure 1 Figure 2 p392-a Figure 5 Figure 6 Figure 7 Figure 8 p397-a p398-a Figure 13 Figure 14 PMID:3555106

  14. Pancreas transplantation. An immunohistologic and histopathologic examination of 100 grafts.

    PubMed Central

    Sibley, R. K.; Sutherland, D. E.

    1987-01-01

    The authors examined tissues obtained by biopsy, pancreatectomy, and autopsy from 100 pancreas grafts to determine the cause of dysfunction or failure of the graft. Immunohistologic examination of 42 tissues to determine the mononuclear cell phenotypes and Class I and II antigen expression was performed as well. Technical factors--infections, thrombosis, obstruction--accounted for a large number of graft losses, but immunologic-mediated mechanisms resulted in graft dysfunction and failure as well. Pleomorphic inflammatory infiltrates were present in grafts with acute rejection, as well as Silastic and Prolamine duct-obstructed grafts. Criteria useful in the identification of acute rejection from pancreatitis included a more intense, predominantly mononuclear cell infiltration of transformed lymphocytes in the exocrine pancreas and evidence of vascular rejection--endovasculitis or fibrinoid necrosis. Increased expression and/or induction of Class I and II antigens on pancreatic constituents occurred in grafts with evidence of acute rejection, but also with Silastic and prolamine duct-obstructed pancreatitis. An isletitis occurred in 25% of the grafts. Nine of the 25 grafts (36%) with isletitis also had selective loss of beta cells from the islets. Recurrent diabetes mellitus appeared to have developed in these cases, which accounted for loss of graft function. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 PMID:3037911

  15. Extrinsic fiber optic displacement sensors and displacement sensing systems

    DOEpatents

    Murphy, K.A.; Gunther, M.F.; Vengsarkar, A.M.; Claus, R.O.

    1994-04-05

    An extrinsic Fizeau fiber optic sensor comprises a single-mode fiber, used as an input/output fiber, and a multimode fiber, used purely as a reflector, to form an air gap within a silica tube that acts as a Fizeau cavity. The Fresnel reflection from the glass/air interface at the front of the air gap (reference reflection) and the reflection from the air/glass interface at the far end of the air gap (sensing reflection) interfere in the input/output fiber. The two fibers are allowed to move in the silica tube, and changes in the air gap length cause changes in the phase difference between the reference reflection and the sensing reflection. This phase difference is observed as changes in intensity of the light monitored at the output arm of a fused biconical tapered coupler. The extrinsic Fizeau fiber optic sensor behaves identically whether it is surface mounted or embedded, which is unique to the extrinsic sensor in contrast to intrinsic Fabry-Perot sensors. The sensor may be modified to provide a quadrature phase shift extrinsic Fizeau fiber optic sensor for the detection of both the amplitude and the relative polarity of dynamically varying strain. The quadrature light signals may be generated by either mechanical or optical means. A plurality of the extrinsic sensors may connected in cascade and multiplexed to allow monitoring by a single analyzer. 14 figures.

  16. Early Tertiary subsidence and sedimentary facies - Northern Sirte Basin, Libya

    SciTech Connect

    Gumati, Y.D.; Kanes, W.H.

    1985-12-01

    The subsidence curves and subsidence rate curves for the Sirte basin, constructed from the stratigraphic record, show that subsidence was continuous throughout Late Cretaceous and Tertiary times, reaching a maximum during the Paleocene and Eocene, when a major reactivation of faults occurred. Shales and carbonates were deposited during all of the Late Cretaceous and Tertiary. Abrupt lateral facies changes occur from the platform areas toward the deeper troughs along with steep downdip thickening. The absence of upper Paleozoic and lower Mesozoic sediments suggests that the area was domed, faulted, and eroded during the late Mesozoic. As a result of crustal extension during the Paleocene, a marked lithologic and structural change occurred. The Heira Shale succeeded the Kalash Limestone in the Marada trough. Reactivation of the earlier faults, accompanied by an increase in the sediment supply from the south, caused these lower Paleocene shales to cover the entire area, with the exception of the old highs where carbonate deposition continued. An intercalation of shales and carbonates provides a sensitive indicator of change of depth and sediment type. 14 figures.

  17. Rift basins of interior Sudan: petroleum exploration and discovery

    SciTech Connect

    Schull, T.J.

    1988-10-01

    The sedimentary basins of interior Sudan are characterized by thick nonmarine clastic sequences of Jurassic(.)-Cretaceous and Tertiary age. Over 45,000 ft (13,716 m) of sediment was deposited in the deepest trough and extensive basinal areas are underlain by more than 20,000 ft (6096 m) of sedimentary rocks. The depositional sequences include thick lacustrine shales and claystones, flood plain claystones, and lacustrine, fluvial, and alluvial sandstones and conglomerates. Those lacustrine claystones deposited in a suboxic environment provide good oil-prone source rocks. Reservoir sandstones have been found in a wide variety of nonmarine sandstone facies. The extensional tectonism that formed these basins began in the Jurassic(.)-Early Cretaceous. Movement along major fault trends continued intermittently into the Miocene. This deformation resulted in a complex structural history that led to the formation of several deep fault-bounded troughs, major interbasinal highs, and complex basin flanks. This tectonism has created a wide variety of structures, many of which have become effective hydrocarbon traps. During the past eight years, several important oil discoveries have been made. Significant accumulations have been delineated in the Heglig and Unity areas, where estimated recoverable reserves are 250-300 million bbl of oil. 14 figures.

  18. Nutrient influences on leaf photosynthesis

    SciTech Connect

    Longstreth, D.J.; Nobel, P.S.

    1980-01-01

    The net rate of CO/sub 2/ uptake for leaves of Gossypium hirsutum L. was reduced when the plants were grown at low concentrations of NO/sub 3//sup -/, PO/sub 4//sup 2 -/, or K/sup +/. The water vapor conductance was relatively constant for all nutrient levels, indicating little effect on stomatal response. Although leaves under nutrient stress tended to be lower in chlorophyll and thinner, the ratio of mesophyll surface area to leaf area did not change appreciably. Thus, the reduction in CO/sub 2/ uptake rate at low nutrient levels was due to a decrease in the CO/sub 2/ conductance expressed per unit mesophyll cell wall area (g/sub CO/sup cell//sub 2/). The use of g/sub CO//sup cell//sub 2/ and nutrient levels expressed per unit of mesophyll cell wall provides a new means of assessing nutrient effects on CO/sub 2/ uptake of leaves. 14 figures, 1 table.

  19. Recovery of metal oxides from fly ash. Volume 3. Commercial facility design criteria. Final report

    SciTech Connect

    Wilder, R.F.; Barrett, P.J.; Henslee, L.W. Jr.

    1984-06-01

    An engineering, cost and financial evaluation study was carried out for a conceptual commercial plant to process fly ash into marketable metal oxides by the direct HCl acid leach process. The proposed plant site was adjacent to the TVA Kingston, Tennessee power plant and was sized to process 1 million tons of ash (dry basis) per year. The capital cost requirements for the HCl direct acid leach (DAL) optimized process plant were estimated to be $244,390,000. Based upon the reported Kingston plant fly ash analysis and extractability, the conceptual commercial plant would annually produce about 158,000 TPY of alumina, 102,000 TPY of ferric oxide, 46,000 TPY of gypsum, 81,000 TPY of alkali sulfate salts, 866,000 TPY of spent fly ash and 1,940,000 kWh of excess cogeneration power. Potential long term average revenues were projected to be $126,400,000 per year which would indicate a commercial project's economics may be quite adequate. Volume 1 of this study report presents the investment and operating cost data, revenue considerations and an evaluation of profitability. Volume 2 presents the engineering data and capital cost estimates and Volume 3 presents the commercial facility design criteria. 16 references, 14 figures, 4 tables.

  20. Evaluation of the Steel Creek ecosystem in relation to the proposed restart of the L-Reactor: interim report

    SciTech Connect

    Not Available

    1983-09-01

    This interim report of findings from studies by SREL has updated information on several key components of the Steel Creek ecosystem. We have emphasized two categories of the Steel Creek biota: Endangered Species (American alligator) and species for which environmental degradation within SRP boundaries might result in changes in offsite resource abundance. Wintering waterfowl surveys in the vicinity of the Steel Creek delta have demonstrated a pattern of increased utilization over the duration of these studies (1981-83). Wood stork utilization of SRP swamp areas also appeared to be substantially increased relative to previous years. Thermal alteration of the Steel Creek delta areas will eliminate this area as wood stork foraging habitat. Anadromous fish utilization of the Steel Creek area was also substantially increased in 1983 relative to 1982. The differences in anadromous fish species utilization patterns between 1982 and 1983 are probably a result of the markedly different river flow conditions between the two years. Studies of the American alligator have continued. No further reproduction by alligators has been observed in the Steel Creek system. 24 references, 14 figures, 13 tables.

  1. Cementation and compaction history of synorogenic foreland basin sedimentary rocks from Huaco, Argentina

    SciTech Connect

    Damanti, J.F.; Jordan, T.E.

    1989-07-01

    The Sierra de Huaco exposes the western flank of the Bermejo foreland basin of central western Argentina. The exposed 5400-m section is well dated (14-2.3 Ma) and consists of synorogenic continental strata. Petrographic data combined with decompaction techniques provide first-order estimates of the absolute age of cementation of the sandstones. This information can be used to interpret petroleum migration paths and reservoir potential. Three diagenetic zones have been recognized, each characterized by a dominant cementing material within a distinct framework texture. These textures reflect varying degrees of compaction and framework-grain replacement prior to cementation. The diagenetic histories of the three zones were genetically linked to thrusting in the adjacent Precordillera, changes in depositional environment, and subsurface fluid flow. The depth at which cementation occurred in each zone is constrained by comparison of observed intergrain volume to predicted volumes (for uncemented sands) at any given burial depth. First-order estimates of the absolute age of cementation in each zone were made possible by comparing these relationships with a curve of accumulation history of the decompacted strata. The lowest zone compacted with little interstitial cement for as long as 11 m.y. after deposition. The middle zone was cemented within 3 m.y. after deposition. The upper zone experienced framework-grain replacement by calcite at very shallow depths within 2 m.y. and experienced little compaction. 14 figures, 1 table.

  2. Role of petroleum reserves in the development of the Mexican economy revisited

    SciTech Connect

    Valdes, R.M.

    1986-01-01

    The importance of petroleum reserves in the development of Mexico's economy since 1976 was examined. Large oil discoveries in the mid 1970's allowed Mexico to overcome the 1976 economic crisis and propelled the country to a brief period of rapid economic expansion during 1978-1981. However, mismanagement and capital flight wasted much of Mexico's oil resources and these factors combined with the increasing burden of the foreign debt service and weakening oil markets eventually led the country to the 1982 economic crisis. This crisis has become the worst in half a century because for four years the country has been unable to find a way out of its current economic impasse. This has resulted in sharply falling standards of life and great uncertainty about the economic viability of the country. In contrast to the 1976 crisis, no painless solution exists to the current one. Only profound structural changes will solve permanently the problems facing Mexico now. 37 references, 14 figures, 2 tables.

  3. Accretion of the south Florida platform, late Quaternary development

    SciTech Connect

    Holmes, C.W.

    1985-02-01

    Stratigraphic information from high-resolution seismic data obtained across the southwest Florida platform indicates that the modern shelf is a constructional platform with Pliocene(.)-Pleistocene and Holocene sediments resting on an eroded karstic Miocene platform. The Miocene surface dips away from the coastline with significant breaks in slope occurring at the center of the shelf and at the shelf edge. At the southwest corner of the platform, this surface crops out to form a terrace. This terrace lies along the west-facing continental slope of the Florida shelf and is progressively buried to the south by younger deposits - reefs and sediment - so that it has no surface expression in the Florida Straits. A paired reef complex rests on the thickest post-Miocene sediments that mark the edge of the modern shelf. The deepest reef forms a well-developed escarpment with its crest buried by approximately 15 m (50 ft) of sediment. The shallower reef is a low swale over most of its extent but developed into a large reef-spit complex (Howell Hook) in the central part of the study area. Within the Pliocene-Pleistocene and Holocene sediments, two stratigraphic units can be delineated: (1) a lower progradational unit of Pliocene-Pleistocene(.) age that can be traced under the shelf-edge reef and continuously onlaps the Miocene(.) surface, and (2) an upper unit of late Pleistocene-Holocene age which is composed of reef and pelagic sediment. 14 figures.

  4. Measurements of heavy quark and lepton lifetimes

    SciTech Connect

    Jaros, J.A.

    1985-02-01

    The PEP/PETRA energy range has proved to be well-suited for the study of the lifetimes of hadrons containing the b and c quarks and the tau lepton for several reasons. First, these states comprise a large fraction of the total interaction rate in e/sup +/e/sup -/ annihilation and can be cleanly identified. Second, the storage rings have operated at high luminosity and so produced these exotic states copiously. And finally, thanks to the interplay of the Fermi coupling strength, the quark and lepton masses, and the beam energy, the expected decay lengths are in the 1/2 mm range and so are comparatively easy to measure. This pleasant coincidence of cleanly identified and abundant signal with potentially large effects has made possible the first measurements of two fundamental weak couplings, tau ..-->.. nu/sub tau/W and b ..-->.. cW. These measurements have provided a sharp test of the standard model and allowed, for the first time, the full determination of the magnitudes of the quark mixing matrix. This paper reviews the lifetime studies made at PEP during the past year. It begins with a brief review of the three detectors, DELCO, MAC and MARK II, which have reported lifetime measurements. Next it discusses two new measurements of the tau lifetime, and briefly reviews a measurement of the D/sup 0/ lifetime. Finally, it turns to measurements of the B lifetime, which are discussed in some detail. 18 references, 14 figures, 1 table.

  5. MESOI Version 2. 0: an interactive mesoscale Lagrangian puff dispersion model with deposition and decay

    SciTech Connect

    Ramsdell, J.V.; Athey, G.F.; Glantz, C.S.

    1983-11-01

    MESOI Version 2.0 is an interactive Lagrangian puff model for estimating the transport, diffusion, deposition and decay of effluents released to the atmosphere. The model is capable of treating simultaneous releases from as many as four release points, which may be elevated or at ground-level. The puffs are advected by a horizontal wind field that is defined in three dimensions. The wind field may be adjusted for expected topographic effects. The concentration distribution within the puffs is initially assumed to be Gaussian in the horizontal and vertical. However, the vertical concentration distribution is modified by assuming reflection at the ground and the top of the atmospheric mixing layer. Material is deposited on the surface using a source depletion, dry deposition model and a washout coefficient model. The model also treats the decay of a primary effluent species and the ingrowth and decay of a single daughter species using a first order decay process. This report is divided into two parts. The first part discusses the theoretical and mathematical bases upon which MESOI Version 2.0 is based. The second part contains the MESOI computer code. The programs were written in the ANSI standard FORTRAN 77 and were developed on a VAX 11/780 computer. 43 references, 14 figures, 13 tables.

  6. Coping with changing risks in utility capital investments

    SciTech Connect

    Geraghty, D.M.

    1984-03-01

    The debate on the efficacy of different types of electric utility investments over the last decade has been fragmentary. There have been advocates of least-cost strategies, improved regulatory techniques, ''small'' versus ''big'' technologies, politically satisfying investments, maximizing long-run benefits, and so on. In addition, many contributors to the debate have pointed out that uncertainty or risk is pervasive throughout all of the investment alternatives and that the proper accounting for risk in investment decision making is crucial. All these positions have merits in their own right but very little has been done to integrate all the pieces of the debate. This article proposes that meaningful analyses and choices between investment decisions cannot be accomplished unless one considers some key characteristics of each investment simultaneously. The first half discusses the importance of some of these key characteristics of utility investments and presents some results of recent analyses. The second half concentrates on one specific characteristic, risk, and suggests ways to manage it for different types of investments. 13 references, 14 figures, 3 tables.

  7. Paleotectonics and hydrocarbon accumulation, Powder River basin, Wyoming

    SciTech Connect

    Slack, P.B.

    1981-04-01

    The Belle Fourche arch, a subtle northeast-trending paleoarch, extends across the central part of the Powder River basin, Wyoming, to the Black Hills uplift. The arch is the result of differential vertical uplift, primarily during Cretaceous time, on numerous northeast-trending structural lineaments. Stratigraphic evidence suggests that the structural lineaments which form the Belle Fourche arch have rejuvenated periodically throughout the Phanerozoic. Evidence includes: (1) localization of Minnelusa Formation (Permian) hydrocarbon production along the crest of the arch; (2) localization of Dakota Formation (Cretaceous) alluvial point-bar production on the crest of the arch; (3) localization of lower Muddy Formation (Cretaceous) channel deposits parallel with, and on the downthrown sides of, lineament trends; (4) abrupt change in depositional strike of upper Muddy Formation (Cretaceous) marine bars close to the arch; (5) superposition of Turner sandstone (Cretaceous) channel deposits along the trends of Muddy channels; and (6) localization of virtually all significant Upper Cretaceous Shannon and Sussex sandstone offshore marine-bar production along the crest of the arch. Subtle uplift along the arch was persistent during at least lower Muddy through Sussex deposition, a period of about 35 m.y. 14 figures.

  8. A beta 1-integrin receptor for fibronectin in human kidney glomeruli.

    PubMed Central

    Kerjaschki, D.; Ojha, P. P.; Susani, M.; Horvat, R.; Binder, S.; Hovorka, A.; Hillemanns, P.; Pytela, R.

    1989-01-01

    The fibronectin receptor (FNR) is a transmembrane heterodimeric glycoprotein which shares a common beta 1-chain with several other members of the integrin family of adhesion receptors. The authors have prepared a membrane fraction of isolated human glomeruli, from which two proteins (apparent molecular weights 120 kd and 140 kd) bound to a fibronectin-column, and were selectively released by the synthetic peptide Arg-Gly-Asp-Ser. These molecules were labeled in immune overlays by an antibody raised against the FNR from human placenta that recognizes both the FNR-specific a-chain and the group-specific beta 1-integrin chain. In sections of normal human kidneys this antibody labeled predominately the mesangia and the peripheral capillary walls of glomeruli by an immunoperoxidase procedure. Quantitative immunoelectron microscopy, using an indirect immunogold procedure, revealed a preferential localization along the cell membranes of mesangial, epithelial, and endothelial cells that face the mesangial matrix or the glomerular basement membrane (GBM). In kidney biopsies from patients with various glomerular diseases (membranous and other forms of glomerulonephritis, minimal change disease) the distribution was similar to that in normal glomeruli. These findings indicate that a beta 1-integrin-related FNR is present in normal and diseased human glomeruli. Images Figure 1-4 Figure 5 Figure 6-10 Figure 11-16 PMID:2521774

  9. Burial history and thermal maturity, Rocky Mountain front ranges, foothills, and foreland, east-central British Columbia and adjacent Alberta, Canada

    SciTech Connect

    Kalkreuth, W.; McMechan, M.

    1988-11-01

    The regional pattern of maturation of Cretaceous strata in the study area was determined from vitrinite-reflectance measurements. Maturation increases from west to east across the Foothills to a maximum near the eastern limit of Foothills deformation and decreases farther east. Maturation along the eastern limit of deformation also decreases northward significantly. Reflectance measurements from Carboniferous strata exposed in the Front Ranges are much lower than values from the Lower Cretaceous near the eastern limit of deformation. Modeling using burial history curves indicates the regional maturation pattern largely reflects variations in the depth and/or duration of burial beneath Maastrichtian-Eocene foredeep deposits. However, differential vertical movements associated with the Peace River arch/embayment in the Carboniferous, Triassic, Early Cretaceous and Maastrichtian-Eocene had an important effect on the maturation pattern. Determined and estimated maturation levels for reservoir strata are consistent with the known occurrences of gas fields and oil pools, except along the relatively unexplored western margin of the study area. There, moderate maturation levels indicate a potential for wet-gas or oil preservation in shallow structures containing Triassic and Lower Carboniferous carbonates in the south. In the north, structures in the western Foothills deforming Triassic strata with lower levels of maturation are breached. 15 figures.

  10. Localization of hepatitis B surface antigen in conventional paraffin sections of the liver. Comparison of immunofluorescence, immunoperoxidase, and orcein staining methods with regard to their specificity and reliability as antigen marker.

    PubMed Central

    Nayak, N. C.; Sachdeva, R.

    1975-01-01

    Hepatitis B antigen (HBAg) has been demonstrated in conventional formalin-fixed paraffin-embedded liver tissue by peroxidase and fluorescent immunostaining as well as by orcein. Complete locational and morphologic identity is seen between material stained by specific immunologic methods and by orcein. The antigen is restricted to the cytoplasm and is generally observed in the hepatocyte; it is present in three morphologic forms. Certain morphologic forms can even be identified in hematoxylin and eosin-stained tissue. Results of immunostaining procedures indicate that the antigen demonstrated in this study consists entirely of surface coat of hepatitis B virus (HBsAg). This seems to be the only component revealed by orcein staining. The latter is considered to be a good marker of the surface antigen and to have certain advantages over immunostaining. It is suggested that suitability of conventional paraffin sections for the detection of HBAg has wide and important implications. Images Figures 1-5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 PMID:55076

  11. Aging with respect to flammability and other properties in fire-retarded ethylene propylene rubber and chlorosulfonated polyethylene

    SciTech Connect

    Salazar, E.A.; Bouchard, D.A.; Furgal, D.T.

    1982-03-01

    The flammability characteristics of ethylene propylene and chlorosulfonated polyethylene rubbers containing fire-retardant additives, aged in different thermal and radiation environments have been studied. Flammability parameters for these materials (time to ignition, mass pyrolysis, buring rate and fuel consumption) when exposed to, and aged in thermal, radiation, and thermal/radiation environments are discussed. Two formulations of each type of rubber are compared. The results are a direct contradiction to expected results based on small-scale flammability tests. They show that the fire-retarding agents used in this investigation do not reduce, and in some cases, contribute to, rubber flammability when exposred to a full-scale fire environment. In addition, the results show that for full-scale fire conditions, the energy required for ignition of chlorosulfonated polyethylene is lower than that required for ethylene propylene rubber; a complete reversal of expected results. The effects of aging on the tensile-elongation properties have been determined. Radiation dose-rate effects are also discussed. Results show that the fire-retardant additives have a negligible influence on the tested materials' tensile-elongation properties and on material aging, regardless of the aging environment. The data obtained, however, may be too limited to show significant dose-rate effects. 15 figures, 9 tables.

  12. Creep cavitation in 304 stainless steel

    SciTech Connect

    Chen, I.W.; Argon, A.S.

    1981-01-01

    Creep cavitation in 304 stainless steel at 0.5 T/sub m/ was investigated. Two specially developed techniques were used to study the nucleation and growth of grain-boundary cavities. It was found that cavities nucleated heterogeneously throughout the creep history and those observed were well in their growth stage. Comparison of these observations with the theory for cavity nucleation requires that a high interfacial stress be present. Experiments suggest that such stress concentrations are present in the early stages of boundary sliding, and in additional transients associated with intermittent sliding of boundaries throughout the creep life. It was found that microstructural variations such as those caused by twins which strongly affect initial particle densities on boundaries can alter cavitation behavior drastically. Our results also show that wedge cracks are the result of accelerated linking of growing cavities in the triple point region of stress concentration and are not a separate phenomenon. Furthermore, at higher strain rates growth of cavities can be accelerated by grain boundary sliding. Lastly, evidence is given to support the view that in engineering alloys which contain complex phas constitutents particularly along grain-boundaries, cavitation in long term service is likely to be caused by cavities nucleated in connection with a prior cold forming operation. 15 figures.

  13. FLUOMEG: a planar finite difference mesh generator for fluid flow problems with parallel boundaries. [In FORTRAN IV

    SciTech Connect

    Kleinstreuer, C.; Patterson, M.R.

    1980-05-01

    A two- or three-dimensional finite difference mesh generator capable of discretizing subrectangular flow regions (planar coordinates) with arbitrarily shaped bottom contours (vertical dimension) was developed. This economical, interactive computer code, written in FORTRAN IV and employing DISSPLA software together with graphics terminal, generates first a planar rectangular grid of variable element density according to the geometry and local kinematic flow patterns of a given fluid flow problem. Then subrectangular areas are deleted to produce canals, tributaries, bays, and the like. For three-dimensional problems, arbitrary bathymetric profiles (river beds, channel cross section, ocean shoreline profiles, etc.) are approximated with grid lines forming steps of variable spacing. Furthermore, the code works as a preprocessor numbering the discrete elements and the nodal points. Prescribed values for the principal variables can be automatically assigned to solid as well as kinematic boundaries. Cabinet drawings aid in visualizing the complete flow domain. Input data requirements are necessary only to specify the spacing between grid lines, determine land regions that have to be excluded, and to identify boundary nodes. 15 figures, 2 tables.

  14. Acid precipitation and drinking water quality in the eastern United States. Final report, November 1981-January 1984

    SciTech Connect

    Taylor, F.; Taylor, J.A.; Symons, G.E.; Collins, J.J.; Schock, M.R.

    1984-01-01

    Research was conducted to provide accurate modern and historical data on drinking water quality and the possible effect of acid precipitation on water samples. Samples of source raw and finished water were collected from more than 300 surface and groundwater supplies in the New England States, New York, New Jersey, Pennsylvania, West Virginia, Virginia, and North Carolina. The samples were analyzed at EPA laboratories. Historical records were obtained dating back to 1886. Acid rain may dissolve harmful elements from soils and from water supply distribution systems. Because soils can alter the character of acid rain through buffering, causal relationships are difficult to identify. A helpful approach to this problem is the use of indices of water supply sensitiviy and corrosiveness. With these indices, drinking water standards, and reliable chemical data, an assessment of water supply characteristics has been accomplished. Though solution products of acid rain in the water supply sources studied do not exceed EPA Primary Drinking Water Regulations, a large number of tests for aluminum showed levels that could be of concern to kidney dialysis patients. Because of the present water quality conditions (low alkalinity and pH) at numerous water sources, future acid deposition could be expected to have a detrimental effect on water quality. 42 references, 15 figures, 42 tables.

  15. Meiotic process and aneuploidy

    SciTech Connect

    Grell, R.F.

    1985-01-01

    The process of meiosis is analyzed by dissecting it into its component parts using the early oocyte of Drosophila as a model. Entrance of the oocytes into premeiotic interphase signals initiation of DNA replication which continues for 30 h. Coincidentally, extensive synaptonemal complexes appear, averaging 50 ..mu..m (132 h), peaking at 75 ..mu..m (144 h) and continuing into early vitellarial stages. Recombinational response to heat, evidenced by enhancement or induction of exchange, is limited to the S-phase with a peak at 144 h coinciding with maximal extension of the SC. Coincidence of synapsis and recombination response with S at premeiotic interphase is contrary to their conventional localization at meiotic prophase. The interrelationship between exchange and nondisjunction has been clarified by the Distributive Pairing Model of meiosis. Originally revealed through high frequencies of nonrandom assortment of nonhomologous chromosomes, distributive pairing has been shown to follow and to be noncompetitive with exchange, to be based on size-recognition, not homology, and as a raison d'etre, to provide a segregational mechanism for noncrossover homologues. Rearrangements, recombination mutants and aneuploids may contribute noncrossover chromosomes to the distributive pool and so promote the nonhomologous associations responsible for nondisjunction of homologues and regular segregation of nonhomologues. 38 references, 15 figures. (ACR)

  16. Late Cretaceous - Cenozoic development of outer continental margin, southwestern Nova Scotia

    SciTech Connect

    Swift, S.A.

    1987-06-01

    The growth pattern for the outer continental margin of Nova Scotia during the Late Cretaceous and Cenozoic was studied using seismic stratigraphy and well data. Sediment accumulation was broadly controlled by temporal changes in relative sea level, but significant spatial and temporal changes in accumulation patterns were caused by changes in sediment supply rate, morphology, erosion by abyssal currents, and salt tectonics. A Jurassic-Early Cretaceous carbonate platform remained exposed until the Late Cretaceous and controlled the location and steepness of the paleoslope until the late Miocene. Local erosion of the outer shelf and slope in the late Paleocene-early Eocene produced chalky fans on the upper rise. The relationship between erosion of the shelf in the late Eocene and early Oligocene, and abyssal current erosion of the upper rise in the Oligocene, is unclear. Seaward extensions of Tertiary shelf-edge canyons are poorly defined except for the Eocene fans. In the Miocene, abyssal currents eroded a bench on the upper continental rise. Subsequently, sediments lapped onto and buried the paleoslope. The lower rise above horizon A/sup u/ (Oligocene) is composed of fans and olistostromes shed from halokinetic uplift of the upper rise. Current eroded unconformities are common in the rise sequence, but the only current deposit is a Pliocene interval (< 300 m) restricted to the lowermost rise. Pleistocene turbidity currents eroded the present canyon morphology. 15 figures, 2 tables.

  17. The Clinical Physiology of Water Metabolism

    PubMed Central

    Weitzman, Richard E.; Kleeman, Charles R.

    1979-01-01

    Water balance is tightly regulated within a tolerance of less than 1 percent by a physiologic control system located in the hypothalamus. Body water homeostasis is achieved by balancing renal and nonrenal water losses with appropriate water intake. The major stimulus to thirst is increased osmolality of body fluids as perceived by osmoreceptors in the anteroventral hypothalamus. Hypovolemia also has an important effect on thirst which is mediated by arterial baroreceptors and by the renin-angiotensin system. Renal water loss is determined by the circulating level of the antidiuretic hormone, arginine vasopressin (AVP). AVP is synthesized in specialized neurosecretory cells located in the supraoptic and paraventricular nuclei in the hypothalamus and is transported in neurosecretory granules down elongated axons to the posterior pituitary. Depolarization of the neurosecretory neurons results in the exocytosis of the granules and the release of AVP and its carrier protein (neurophysin) into the circulation. AVP is secreted in response to a wide variety of stimuli. Change in body fluid osmolality is the most potent factor affecting AVP secretion, but hypovolemia, the renin-angiotensin system, hypoxia, hypercapnia, hyperthermia and pain also have important effects. Many drugs have been shown to stimulate the release of AVP as well. Small changes in plasma AVP concentration of from 0.5 to 4 μU per ml have major effects on urine osmolality and renal water handling. ImagesFigure 5.Figure 12.Figure 15.Figure 16. PMID:394480

  18. Multiple conductances in the large K+ channel from Chara corallina shown by a transient analysis method.

    PubMed Central

    Tyerman, S D; Terry, B R; Findlay, G P

    1992-01-01

    The large conductance K+ channel in the tonoplast of Chara corallina has subconductance states (substates). We describe a method that detects substates by monitoring the time derivative of channel current. Substates near to the full conductance tend to have long durations and high probabilities, while those of smaller amplitude occur with less probability and short duration. The substate pattern is similar in cell-attached, inside-out and outside-out patches over a range of temperatures. The pattern changes at high Ca2+ concentration (10 mol m-3) on the cytoplasmic face of inside-out patches. One substate at approximately 50% of the full conductance is characterized by a high frequency of transitions from the full conductance level. This midstate conductance is not a constant proportion of the full conductance but changes as a function of membrane potential difference (p.d.) showing strong inward rectification. We suggest that the channel is a single pore that can change conformation and/or charge profile to give different conductances. The mean durations of the full conductance level and the midstate decrease as the membrane p.d. becomes more negative. Programs for analysis of channel kinetics based on an half-amplitude detection criterion are shown to be unsuitable for analysis of the K+ channel. Images FIGURE 1 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 FIGURE 15 FIGURE 16 PMID:1504245

  19. Effects of loading on the growth rates of deep stress-corrosion cracks

    SciTech Connect

    Beavers, J.A.; Christman, T.K.

    1990-08-01

    The goal of this research program was to determine the effects of loading on growth of stress-corrosion cracks (SCC) in line pipe steel and whether special loading procedures could actually inhibit crack growth. Of particular interest was the effect of hydrostatic retesting on the subsequent growth of existing cracks. The growth rate experiments showed that the slow-strain rate loading could successfully nucleate a group of fine cracks with depths up to 0.025 inches (0.64 mm). However, the subsequent cyclic loading at typical operating stress levels (lower than experienced during the slow- strain rate loading) produced minimal crack growth and stopped soon after the test was started. The limited growth is believed to be a real phenomenon which means this is not a suitable procedure for the measurement of average crack growth rates. These experiments indicate that cracks grown at high stress (as in the slow-strain rate phase) do not readily propagate at lower stress levels. This may be because of crack closure (compressive crack tip residual stress) induced by the initial higher stress level. If that is true, then hydrostatic retests could inhibit the growth of existing stress-corrosion cracks, especially if the hydrostatic tests are conducted at high stress levels. 15 figures, 3 tabs.

  20. Mechanisms of radiation-induced neoplastic cell transformation

    SciTech Connect

    Yang, T.C.H.; Tobias, C.A.

    1984-04-01

    Studies with cultured mammalian cells demonstrated clearly that radiation can transform cells directly and can enhance the cell transformation by oncogenic DNA viruses. In general, high-LET heavy-ion radiation can be more effective than X and gamma rays in inducing neoplastic cell transformation. Various experimental results indicate that radiation-induced DNA damage, most likely double-strand breaks, is important for both the initiation of cell transformation and for the enhancement of viral transformation. Some of the transformation and enhancement lesions can be repaired properly in the cell, and the amount of irrepairable lesions produced by a given dose depends on the quality of radiation. An inhibition of repair processes with chemical agents can increase the transformation frequency of cells exposed to radiation and/or oncogenic viruses, suggesting that repair mechanisms may play an important role in the radiation transformation. The progression of radiation-transformed cells appears to be a long and complicated process that can be modulated by some nonmutagenic chemical agents, e.g., DMSO. Normal cells can inhibit the expression of transforming properties of tumorigenic cells through an as yet unknown mechanism. The progression and expression of transformation may involve some epigenetic changes in the irradiated cells. 38 references, 15 figures, 1 table.

  1. Chemistry of 2,3-dimethylene-2,3-dihydrofurans and other reactive olefins prepared by the flash vacuum pyrolysis of substituted furylmethyl esters

    SciTech Connect

    Cassady, T.J.

    1985-03-01

    The flash vacuum pyrolysis chemistry of a series of methyl-substituted, furfuryl benzoates and methyl-substituted, 3-furylmethyl benzoates has been investigated. Mechanisms were proposed for the formation of the pyrolysis products, from each of the compounds studied, which involved either ..cap alpha.. or ..beta.. eliminations of benzoic acid after one or more (3,3) sigmatropic shifts of the benzoate group. These reactions provide a method for the preparation of the bis(methylene)-dihydrofurans which are the furan analogs of the ortho- and para-quinodimethanes, an actively investigated group of reactive intermediates. The chemical reactions of the 2,3-bis(methylene)-2,3-dihydrofurans, which were investigated in this study, included thermal dimerization reactions, Diels-Alder reactions and chelatropic reactions with sulfur dioxide. Pyrolysis of diesters of 3,4-bis(hydroxymethyl)-2,5-dimethylfuran formed furanoradialene as the only major, nonpolymeric product. Warming the product solutions to room temperature converted furanoradialene into one (4+2) dimer. Several approaches toward the synthesis of (2.2.2.2.)-(2,3,4,5)furanophane were investigated. The failure to produce the desired furanophane was attributed to a retro(4+4) reaction which occurred during the pyrolysis of 4,4'-bis(acetoxymethyl)-5,5'-dimethyl-(2,2)(2,3)furanophane. 277 references, 15 figures, 6 tables.

  2. Apparatus for weighing and identifying characteristics of a moving vehicle

    DOEpatents

    Muhs, J.D.; Jordan, J.K.; Tobin, K.W. Jr.; LaForge, J.V.

    1993-11-09

    Apparatus for weighing a vehicle in motion is provided by employing a plurality of elongated fiber-optic sensors defined by an optical fiber embedded in an encasement of elastomeric material and disposed parallel to each other on the roadway in the path of moving vehicles. Each fiber-optic sensor is provided with contact grid means which can be selectively altered to provide the fiber-optic sensors with sensitivities to vehicular weight different from each other for weighing vehicles in an extended weight range. Switch means are used in conjunction with the fiber-optic sensors to provide signals indicative of the speed of the moving vehicle, the number of axles on the vehicle, weight distribution, tire position, and the wheelbase of the vehicle. The use of a generally N-shaped configuration of switch means also provides a determination of the number of tires on each axle and the tire footprint. When switch means in this configuration are formed of optical fibers, the extent of light transmission through the fibers during contact with the tires of the vehicle is indicative of the vehicle weight. 15 figures.

  3. Coal unit trains: operations, maintenance, and technology. Volume 4. Costs and benefits of aluminum coal cars. Final report

    SciTech Connect

    Boghani, A.B.

    1984-11-01

    This report examines the costs and benefits to a utility of acquiring aluminum coal cars. After discussing the history of aluminum car production, the report describes in detail the characteristics of several aluminum cars now in use, and the experience of railroads and utilities with them. The effects of acquiring aluminum cars instead of steel cars on the fuel cost, crew cost, maintenance-of-way cost, and car costs (capital and maintenance) are discussed. An illustrative example is given, in which the internal rate of return (IRR) and payback period of the extra investment made to acquire aluminum cars are calculated. A parametric analysis is performed to determine the sensitivity of IRR and payback period to the freight-rate discount for the aluminum car, the inflation rate, the purchase price of aluminum and steel cars, their maintenance costs, bad order ratios, car lives, salvage values, trip length, and car utilization. The study concludes that the aluminum cars can be an excellent investment, provided a reasonable freight-rate discount is obtained. The first cost of an aluminum car compared to that of a steel car, its estimated downtime, its estimated maintenance cost, and the anticipated degree of its utilization are also shown to significantly affect the attractiveness of the extra investment. In addition, the study reveals that some aluminum cars have proved more durable in service than others. Thus, the importance of a thorough evaluation of the design of the aluminum cars being offered is demonstrated. 11 references, 15 figures, 8 tables.

  4. Capillary pressure techniques: application to exploration and development geology

    SciTech Connect

    Jennings, J.B.

    1987-10-01

    Capillary pressure can be viewed as the pressure required to drive a fluid through a pore throat and displace the pore wetting fluid, with greater pressure being required as the pore throat becomes smaller. The size and distribution of pore throats within a host rock control its capillary pressure characteristics, which in turn control fluid behavior in the pore system. Mercury-injection capillary pressure curves, which measure capillarity, are obtained by injecting mercury into sample plugs to produce a plot of injection pressure vs. mercury saturation. The resulting capillary pressure curves can provide qualitative assessments of reservoir rock using such calculated values as pore-throat sorting, reservoir grade, and oil columns required to obtain 50 and 75% oil saturations. Regional capillary pressure maps of these calculated values identify a north-south trend of favorable reservoir rock along the state line between Montana and North Dakota in the third porosity (C) zone of the Ordovician Red River Formation. Oil migration and trapping can be significantly controlled by capillary pressure. By understanding capillarity, they can obtain better insight on the nature of reservoir rock, oil accumulations, and permeability relationships. 15 figures, 1 table.

  5. Design and operation of a passive neutron monitor for assaying the TRU content of solid wastes

    SciTech Connect

    Brodzinski, R.L.; Brown, D.P.; Rieck, H.G. Jr.; Rogers, L.A.

    1984-02-01

    A passive neutron monitor has been designed and built for determining the residual transuranic (TRU) and plutonium content of chopped leached fuel hulls and other solid wastes from spent Fast Flux Test Facility (FFTF) fuel. The system was designed to measure as little as 8 g of plutonium or 88 mg of TRU in a waste package as large as a 208-l drum which could be emitting up to 220,000 R/hr of gamma radiation. For practical purposes, maximum assay times were chosen to be 10,000 sec. The monitor consists of 96 /sup 10/BF/sub 3/ neutron sensitive proportional counting tubes each 5.08 cm in diameter and 183 cm in active length. Tables of neutron emission rates from both spontaneous fission and (..cap alpha..,n) reactions on oxygen are given for all contributing isotopes expected to be present in spent FFTF fuel. Tables of neutron yeilds from isotopic compositions predicted for various exposures and cooling times are also given. Methods of data reduction and sources, magnitude, and control of errors are discussed. Backgrounds and efficiencies have been measured and are reported. A section describing step-by-step operational procedures is included. Guidelines and procedures for quality control and troubleshooting are also given. 13 references, 15 figures, 4 tables.

  6. Magnetic resonance imaging of the central nervous system in children with a new nonionic gadolinium contrast agent--gadoteridol injection (ProHance).

    PubMed Central

    Byrd, S. E.; Darling, C. F.; Wilczynski, M. A.

    1993-01-01

    This article reports the results of clinical testing in pediatric patients of a new contrast agent, gadoteridol injection (ProHance), developed by Squibb Diagnostic as a nonionic gadolinium agent for use in magnetic resonance imaging (MRI). Thirteen children (four girls and nine boys) ranging in age from 10 to 18 years were enrolled in the study. The children had MR studies of the brain and/or spine with T1-weighted, T2-weighted, and postgadoteridol injection T1-weighted sequences. Five children had primary brain or spine neoplasms, three children had metastatic disease to the central nervous system, one child had a recurrent brain neoplasm and spinal canal metastasis, one child had an arteriovenous malformation, and two children were normal on the MRI studies. No minor or major reactions to gadoteridol injection developed in the 13 patients. Gadoteridol injection provided excellent delineation and enhancement of the arteriovenous malformation and all of the primary and secondary neoplasms of the central nervous system except for one case of a grade 1 glioma of the midbrain. Gadoteridol injection is a safe and excellent contrast agent for use in MRI. Images Figures 1-5 Figures 6-10 PMID:8496990

  7. Design characteristics of the hydrocyclone for the recovery of coal fines

    SciTech Connect

    Davis, P.K.; Clendenin, H.B.; Peter, M.M.

    1984-01-01

    The relevant design parameters and flow variables of the standard hydrocyclone have been identified. Two experimental systems have been designed and constructed so that the flow rate, inlet area, vortex finder length and diameter, underflow diameter, length of hydrocyclone chamber and cone angle can all be varied, one at a time, while all the other variables are held constant. Dimensional analysis was used to guide the experiments. Initially spheres were used to model solid particles. Data has been taken using spheres ranging in size from 0.03175 m to 0.09525 m with specific gravities varying from 1.05 to 2.10. This range of specific gravities was chosen so as to contain the specific gravity range of coal which varies from 1.2 to 1.6. The specific gravities of the waste materials in gob (clay, shale, pyrite and sandstone) are greater than 2.00. It was later shown that the data taken using spheres compare well with random shaped coal particles with approximately the same mean diameters as the spheres. The sphere data can be used to select a hydrocyclone configuration to perform a specific separation task. In this research, the sphere data was used as a guide to select a configuration to separate coal fines from gob material. Good coal fines recovery from gob samples has been achieved on a batch basis. An an example, Table 1 gives data from one sample showing a combined recovery of 99% by weight with a product rating of 0.95. Another significant finding in this research is that dynamic similitude as predicted by dimensional analysis can be verified using the two experimental systems with hydrocyclones with different diameters. Thus the data taken can be used to scale up or down as the need arises. 10 references, 13 figures, 1 table.

  8. Technical and economic feasibility of utilizing apple pomace as a boiler feedstock

    SciTech Connect

    Sargent, S.A.

    1983-01-01

    Apple pomace or presscake, was evaluated for suitability as a boiler feedstock for Michigan firms processing apple juice. Based upon the physical and chemical characteristics of pomace, handling/direct combustion systems were selected to conform with operating parameters typical of the industry. Fresh pomace flow rates of 29,030 and 88,998 kg/day (64,000 and 194,000 lb/day) were considered as representative of small and large processors, respectively, and the material was assumed to be dried to 15% moisture content (wet basis) prior to storage and combustion. Boilers utilizing pile-burning, fluidized-bed-combustion, and suspension-firing technologies were sized for each flow rate, resulting in energy production of 2930 and 8790 kW (10 and 30 million Btu/h), respectively. A life-cycle cost analysis was performed giving Average Annual Costs for the three handling/combustion system combinations (based on the Uniform Capital Recovery factor). An investment loan at 16% interest with a 5-year payback period was assumed. The break-even period for annual costs was calculated by anticipated savings incurred through reduction of fossil-fuel costs during a 5-month processing season. Large processors, producing more than 88,998 kg pomace/day, could economically convert to a suspension-fired system substituting for fuel oil, with break-even occurring after 4 months of operation of pomace per year. Small processors, producing less than 29,030 kg/day, could not currently convert to pomace combustion systems given these economic circumstances. A doubling of electrical-utility costs and changes in interest rates from 10 to 20% per year had only slight effects on the recovery of Average Annual Costs. Increases in fossil-fuel prices and the necessity to pay for pomace disposal reduced the cost-recovery period for all systems, making some systems feasible for small processors. 39 references, 13 figures, 10 tables.

  9. Swelling and dissolution of cellulose in amine oxide/water systems

    SciTech Connect

    Chanzy, H.; Noe, P.; Paillet, M.; Smith, P.

    1983-01-01

    The swelling behavior and the dissolution process of various cellulosic fibers, both native and regenerated, in N-methylmorpholine N-oxide (MMNO), dimethylethanolamine N-oxide (DMEAO), and mixtures thereof were studied in the presence of various amounts of water. The principal tools in this investigation were optical microscopy and wide-angle X-ray scattering (WAXS). The two amine oxides could either dissolve or only swell cellulose, depending on the water concentration, which was found to be of critical importance. Three domains of water concentration were found important. When only a few percent water was present, cellulose fibers, such as ramie, cotton, rayon, etc., dissolved readily without noticeable swelling in the amine oxide/water system brought above its melting point. At a relatively high water concentration (e.g., 18% w/w for MMNO), the cellulose fibers exhibited an extensive swelling (up to sevenfold increase in the fiber diameter) but no dissolution. In that case, the removal of the swelling agent showed that the initial native cellulose fibers were converted into an unoriented cellulose II structure. With still greater water content (e.g., 20% and more for MMNO or 15% for DMEAO), only partial swelling was observed, and the native cellulose fibers recovered their initial oriented cellulose I structure after removal of the swelling medium. X-ray investigations provided no evidence forthe formation of cellulose/solvent complexes in the swollen fibers. A relatively large decrease of the cellulose I (110) reflection was found in the WAXS patterns of the gels. This is interpreted as due to a preferential cleavage of the cellulose crystals along the corresponding plane when the cellulose fibers are exposed to the swelling forces of the amine oxide/water systems. 29 references, 13 figures, 1 table.

  10. Study of nonlinear waves described by the cubic Schroedinger equation

    SciTech Connect

    Walstead, A.E.

    1980-03-12

    The cubic Schroedinger equation (CSE) is ubiquitous as a model equation for the long-time evolution of finite-amplitude near-monochromatic dispersive waves. It incorporates the effects of the radiation field pressure on the constitutive properties of the supporting medium in a self-consistent manner. The properties of the uniformly transiating periodic wave solutions of the one-dimensional CSE are studied here. These (so-called cnoidal) waves are characterized by the values of four parameters. Whitham's averaged variational principle is used to derive a system of quasilinear evolution equations (the modulational equations) for the values of these parameters when they are slowly varying in space and time. Explicit expressions for the characteristic velocities of the modulational equations are obtained for the full set of cnoidal waves. Riemann invariants are obtained for several limits for the stable case, and growth rates are obtained for several limits, including the solitary wave chain, for the unstable case. The results for several nontrivial limiting cases agree with those obtained by independent methods by others. The dynamics of the CSE generalized to two spatial dimensions are studied for the unstable case. A large class of similarity solutions with cylindrical symmetry are obtained systematically using infinitesimal transformation group techniques. The methods are adapted to obtain the symmetries of the action functional of the CSE and to deduce nine integral invariants. A numerical study of the self-similar solutions reveals that they are modulationally unstable and that singularities dominate the dynamics of the CSE in two dimensions. The CSE is derived using perturbation theory for a specific problem in plasma physics: the evolution of the envelope of a near-monochromatic electromagnetic wave in a cold magnetized plasma. 13 figures, 2 tables.

  11. Characterization of indoor particle sources: A study conducted in the metropolitan Boston area.

    PubMed Central

    Abt, E; Suh, H H; Allen, G; Koutrakis, P

    2000-01-01

    An intensive particle monitoring study was conducted in homes in the Boston, Massachusetts, area during the winter and summer of 1996 in an effort to characterize sources of indoor particles. As part of this study, continuous particle size and mass concentration data were collected in four single-family homes, with each home monitored for one or two 6-day periods. Additionally, housing activity and air exchange rate data were collected. Cooking, cleaning, and the movement of people were identified as the most important indoor particle sources in these homes. These sources contributed significantly both to indoor concentrations (indoor-outdoor ratios varied between 2 and 33) and to altered indoor particle size distributions. Cooking, including broiling/baking, toasting, and barbecuing contributed primarily to particulate matter with physical diameters between 0.02 and 0.5 microm [PM((0.02-0.5))], with volume median diameters of between 0.13 and 0.25 microm. Sources of particulate matter with aerodynamic diameters between 0.7 and 10 microm [PM((0.7-10))] included sautéing, cleaning (vacuuming, dusting, and sweeping), and movement of people, with volume median diameters of between 3 and 4.3 microm. Frying was associated with particles from both PM((0.02-0.5)) and PM((0.7-10)). Air exchange rates ranged between 0.12 and 24.3 exchanges/hr and had significant impact on indoor particle levels and size distributions. Low air exchange rates (< 1 exchange/hr) resulted in longer air residence times and more time for particle concentrations from indoor sources to increase. When air exchange rates were higher (> 1 exchange/hr), the impact of indoor sources was less pronounced, as indoor particle concentrations tracked outdoor levels more closely. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 PMID:10620522

  12. Comparative assessment of TRU waste forms and processes. Volume I. Waste form and process evaluations

    SciTech Connect

    Ross, W.A.; Lokken, R.O.; May, R.P.; Roberts, F.P.; Timmerman, C.L.; Treat, R.L.; Westsik, J.H. Jr.

    1982-09-01

    This study provides an assesses seven waste forms and eight processes for immobilizing transuranic (TRU) wastes. The waste forms considered are cast cement, cold-pressed cement, FUETAP (formed under elevated temperature and pressure) cement, borosilicate glass, aluminosilicate glass, basalt glass-ceramic, and cold-pressed and sintered silicate ceramic. The waste-immobilization processes considered are in-can glass melting, joule-heated glass melting, glass marble forming, cement casting, cement cold-pressing, FUETAP cement processing, ceramic cold-pressing and sintering, basalt glass-ceramic processing. Properties considered included gas generation, chemical durability, mechanical strength, thermal stability, and radiation stability. The ceramic products demonstrated the best properties, except for plutonium release during leaching. The glass and ceramic products had similar properties. The cement products generally had poorer properties than the other forms, except for plutonium release during leaching. Calculations of the Pu release indicated that the waste forms met the proposed NRC release rate limit of 1 part in 10/sup 5/ per year in most test conditions. The cast-cement process had the lowest processing cost, followed closely by the cold-pressed and FUETAP cement processes. Joule-heated glass melting had the lower cost of the glass processes. In-can melting in a high-quality canister had the highest cost, and cold-pressed and sintered ceramic the second highest. Labor and canister costs for in-can melting were identified. The major contributor to costs of disposing of TRU wastes in a defense waste repository is waste processing costs. Repository costs could become the dominant cost for disposing of TRU wastes in a commercial repository. It is recommended that cast and FUETAP cement and borosilicate glass waste-form systems be considered. 13 figures, 16 tables.

  13. Use of corn distiller's solubles from an ethanol plant for aquaculture

    SciTech Connect

    Kohler, C.C.

    1984-06-01

    Wet stillage can economically be separated into two fractions: distiller's grain and distiller's solubles. Wet corn distiller's grain has shown potential as a feed supplement for ruminants, swine, and poultry. However, the soluble fraction (with suspended particles) is of little food value to terrestrial animals because of its high water content; it is not generally economically feasible to concentrate it further. The purpose of this project is to determine if the soluble by-product could potentially be used as a food source in an aquatic environment where its high water content would not necessarily pose an impediment. Studies have shown that corn distiller's solubles are not highly toxic to aquatic organisms at concentrations ranging up to 10,000 ppM. However, the high biological oxygen demand of the material requires that it be administered to ponds at rates less than 2000 ppM on a daily basis. Golden shiners were observed to actively consume the particulates of the corn distiller's solubles. Direct consumption of the particulates by fish makes the use of corn distiller's solubles in aquaculture much more attractive than if the by-product only serves to increase pond fertility. Despite the minimum amount of food material added to the ponds, production of shrimp and fish was favorable over the 4 month growing periods. Golden shiners reared in the same ponds as shrimp had production rates equivalent to 130 kg ha/sup -1/. Monoculture of shrimp at higher densities (3000 to 5000 shrimp stocked per pond versus 2000 in 1982) resulted in an average production equivalent to approximately 228 kg ha/sup -1/, with individual shrimp averaging 10.5 g. Based on estimated wholesale prices of $10.00 and $7.75 per kilogram for frozen shrimp and live fish, respectively, the gross profit margin would have exceeded $2000 ha/sup -1/ both years. 25 references, 13 figures, 13 tables.

  14. Visualization of drug-nucleic acid interactions at atomic resolution. IX. Structures of two N,N-dimethylproflavine: 5-iodocytidylyl (3'-5') guanosine crystalline complexes

    SciTech Connect

    Bhandary, K.K.; Sakore, T.D.; Sobell, H.M.; King, D.; Gabbay, E.J.

    1984-01-01

    This paper describes two complexes containing N,N-dimethylproflavine and the dinucleoside monophosphate, 5-iodocytidylyl(3'-5')guanosine (iodoCpG). The first complex is triclinic, space group P1, with unit cell dimensions a = 11.78 A, b = 14.55 A, c = 15.50 A, ..cap alpha.. = 89.2/sup 0/, ..beta.. 86.2/sup 0/, ..gamma.. = 96.4/sup 0/. The second complex is monoclinic, space group P2/sub 1/, with a = 14.20 A, b = 19.00 A, c = 20.73 A, ..beta.. = 103.6/sup 0/. Both structures have been solved to atomic resolution and refined by Fourier and least squares methods. The first structure has been refined anisotropically to a residual of 0.09 on 5025 observed reflections using block diagonal least squares, while the second structure has been refined isotropically to a residual of 0.13 on 2888 reflections with full matrix least squares. The asymmetric unit in both structures contains two dimethylproflavine molecules and two iodoCpG molecules; the first structure has 16 water molecules (a total of 134 non-hydrogen atoms), while the second structure has 18 water molecules (a total of 136 non-hydrogen atoms). Both structures demonstrate intercalation of dimethylproflavine between base-paired iodoCpG dimers. In addition, dimethylproflavine molecules stack on either side of the intercalated duplex, being related by a unit cell translation along b and a axes, respectively. 16 references, 13 figures, 5 tables.

  15. Experimental extrinsic allergic alveolitis and pulmonary angiitis induced by intratracheal or intravenous challenge with Corynebacterium parvum in sensitized rats.

    PubMed Central

    Yi, E. S.; Lee, H.; Suh, Y. K.; Tang, W.; Qi, M.; Yin, S.; Remick, D. G.; Ulich, T. R.

    1996-01-01

    Extrinsic allergic alveolitis and pulmonary sarcoidosis are granulomatous diseases of the lung for which clinical presentation and anatomic site of granuloma formation differ. Extrinsic allergic alveolitis is caused by inhaled antigens, whereas the nature and source of the inciting antigen in sarcoidosis is unknown. To test the hypothesis that the route via which antigen is introduced to the lung contributes to the clinicopathological presentation of pulmonary granulomatous disease, rats immunized with intravenous (i.v.) Corynebacterium parvum were challenged after 2 weeks with either intratracheal (i.t.) or i.v. C. parvum. The granulomatous inflammation elicited by i.t. challenge predominantly involved alveolar spaces and histologically simulated extrinsic allergic alveolitis. In contrast, the inflammation induced by i.v. challenge was characterized by granulomatous angiitis and interstitial inflammation simulating sarcoidosis. Elevations of leukocyte counts and TNF levels in bronchoalveolar fluid, which reflect inflammation in the intra-alveolar compartment, were much more pronounced after i.t. than after i.v. challenge. Tumor necrosis factor, interleukin-6, CC chemokine, CXC chemokine, and adhesion molecule mRNA and protein expression occurred in each model. In conclusion, i.t. or i.v. challenge with C. parvum in sensitized rats caused pulmonary granulomatous inflammation that was histologically similar to human extrinsic allergic alveolitis and sarcoidosis, respectively. Although the soluble and cellular mediators of granulomatous inflammation were qualitatively similar in both disease models, the differing anatomic source of the same antigenic challenge was responsible for differing clinicopathological presentations. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 11 Figure 13 Figure 12 Figure 14 PMID:8863677

  16. An experimental approach to the study of intraocular Toxocara canis.

    PubMed Central

    Luxenberg, M N

    1979-01-01

    An experimental study of nematode endophthalmitis due to T canis and review of the literature has been presented. Six owl monkeys were infected either by nasogastric tube using embryonated T canis eggs or by carotid or intravitreal injection of second stage larvae. The clinical manifestations, especially ocular, were observed and various diagnostic tests performed. Only minimal or no intraocular changes were seen after systemic infection but significant abnormalities such as retinal hemorrhages and venous dilation were noted after intravitreal infection. Motile larvae were observed in the lenses of three eyes and in the vitreous of five eyes and, probably a sixth, after intravitreal injection. The intensity and timing of the intraocular reaction seemed to correlate with the infecting dose and apparent disappearance of larvae from the eye. Pathologic confirmation of larvae in the lens was obtained in one eye. A marked inflammatory reaction occurred in eyes receiving intraocular infection but none was seen in eyes with only systemic infectin. Various laboratory and serologic studies were performed, including the ELISA test, which were used to evaluate systemic as well as intraocular responses to infection with T canis. The two monkeys infected by nasogastric tube gave a positive ELISA response in the serum but intraocular fluids gave a negative response in all monkeys including those infected syst:mically and/or intraocularly. Problems in the understanding of clinical aspects of the disease, laboratory diagnosis and treatment are discussed. The need for future experimental studies is emphasized. Images FIGURE 1 A FIGURE 1 B FIGURE 1 C FIGURE 2 A FIGURE 2 B FIGURE 2 C FIGURE 2 D FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 A FIGURE 6 B FIGURE 7 FIGURE 8 FIGURE 9 A FIGURE 9 B FIGURE 10 FIGURE 11 FIGURE 12 FIGURE 13 FIGURE 14 PMID:120993

  17. Human aortic fibrolipid lesions. Progenitor lesions for fibrous plaques, exhibiting early formation of the cholesterol-rich core.

    PubMed Central

    Bocan, T. M.; Guyton, J. R.

    1985-01-01

    The early development of the lipid-rich core and other features of atherosclerotic fibrous plaques has been elucidated by examining discrete, small regions of raised intima in human aorta, which often bear a resemblance to both fatty streaks and fibrous plaques. Approximately one-fourth of small raised lesions (less than 16 sq mm of surface area) contained little or no stainable lipid, while three-fourths had a characteristic appearance, which included a superficial layer of foam cells, a core of noncrystalline and/or crystalline lipid, and a developed or developing collagenous cap. Total intimal volumes of the lipid-containing lesions, termed "fibrolipid lesions," ranged from 3 to 43 microliters, with the majority less than 16 microliters. Core lipid in the smallest lesions was located in the musculoelastic layer of the intima. In larger lesions the core extended luminally into the elastic hyperplastic layer, and cholesterol crystals were found more frequently. Total cholesterol concentration in fibrolipid lesions was similar to that in fatty streaks; however, the ratio of unesterified to total cholesterol was relatively high, similar to that found in fibrous plaques. It is concluded that 1) the formation of a lipid-rich core and cholesterol crystallization are early events in the development of many raised lesions; 2) the consistent association between the superficial layer of foam cells and the deep-lying lipid-rich core raises the possibility of an influence, possibly indirect, of foam-cell lipid metabolism on core formation; and 3) the fibrolipid lesion may represent one stage in a potential transitional morphologic sequence between fatty streak and fibrous plaque. Images Figure 2 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 Figure 10 Figure 11 Figure 12 Figure 13 Figure 14 PMID:4025509

  18. Precambrian to Jurassic rocks of Arabian Gulf and adjacent areas: their facies, depositional setting, and hydrocarbon habitat

    SciTech Connect

    Alsharhan, A.S.; Kendal, C.G.S.C.

    1986-08-01

    The first sediments to onlap the metamorphosed Precambrian Arabian shield were Infracambrian (Proterozoic) to Middle Cambrian carbonates, clastics, and evaporites. The oldest Arabian reservoir rocks occur in the Precambrian to lower Paleozoic Era Salt of the Huqf Group, which forms the Birba field of Oman. The Middle Cambrian sequence was followed by Late Cambrian through Early Permian marine sandstones and continental to littoral siltstones and variegated shales. The first commercial oil discovered in the Arabian Gulf region occurs in fluvial sands of the Ordovician to Permian Haima and Haushi Groups of the Marmul field in south Oman. These strata are also productive in other fields and are sealed by unconformable contact with the Al Khlata Formation or beneath shale of the Albian Nahr Umr Formation. The deeply buried kerogen sediments of the Huqf Group to the southeast are believed to be the source rocks for these fields of south Oman. The Late Permian to Triassic deposits of the Arabian Peninsula are mainly widespread carbonates and evaporites that were deposited during a period of relative tectonic stability. Their deposition on an epeiric shelf was punctuated by a series of transgressions and regressions. Significant gas reserves have been proven in deep wells in the Arabian Gulf. These wells penetrate large deep structures in the Permian Khuff shelf carbonates. These carbonates have developed secondary porosity and lie beneath interbedded shale and dolomites of the Sudair or Suwei Formation. The source of gas in the Khuff is unknown but could lie in more deeply buried formations. The large deep structures of the Khuff are considered to be among the most attractive for gas potential in the region today. 14 figures, 2 tables.

  19. Myth of nuclear explosions at waste disposal sites

    SciTech Connect

    Stratton, W.R.

    1983-10-01

    Approximately 25 years ago, an event is said to have occurred in the plains immediately west of the southern Ural mountains of the Soviet Union that is being disputed to this very day. One person says it was an explosion of nuclear wastes buried in a waste disposal site; other people say it was an above-ground test of an atomic weapon; still others suspect that an alleged contaminated area (of unknown size or even existence) is the result of a series of careless procedures. Since the event, a number of articles about the disposal-site explosion hypothesis written by a Soviet exile living in the United Kingdom have been published. Although the Soviet scientist's training and background are in the biological sciences and his knowledge of nuclear physics or chemistry is limited, people who oppose the use of nuclear energy seem to want to believe what he says without question. The work of this Soviet biologist has received wide exposure both in the United Kingdom and the United States. This report presents arguments against the disposal-site explosion hypothesis. Included are discussions of the amounts of plutonium that would be in a disposal site, the amounts of plutonium that would be needed to reach criticality in a soil-water-plutonium mixture, and experiments and theoretical calculations on the behavior of such mixtures. Our quantitative analyses show that the postulated nuclear explosion is so improbable that it is essentially impossible and can be found only in the never-never land of an active imagination. 24 references, 14 figures, 5 tables.

  20. Supermolecular structure of cellulose: stepwise decrease in LODP and particle size of cellulose hydrolyzed after chemical treatment. [Leveling-off degree of polymerization

    SciTech Connect

    Yachi, T.; Hayashi, J.; Takai, M.; Shimizu, Y.

    1983-01-01

    It was observed by electron microscopy that rayons hydrolyzed with 2.4 N HCl at 100/sup 0/C for 2 h, followed by ultrasonic treatment were split into homogeneous particles having a size of about 200 A(2000A). In the previous work with rayons, crystallite length, long period, and chain length calculated from their LODP were all about 200 A(2000A), regardless of the type of rayon. The agreement between particle size and length suggested strongly that a rayon microfibril has a periodic structure along its axis at intervals of about A(2000A). Celluloses II, III, and IV and cellulose regenerated from its esters were derived both from native cellulose and rayons in the fibrous state. After hydrolysis, all the modifications derived from native cellulose showed an LODP of about 80 and rod-like fragments which showed a maximum at 400 A(2000A) in the frequency distribution of their lengths. All of the modifications, except mercerized native cellulose, showed a meridional small-angle reflection corresponding to 400 A(2000A). All the modifications from rayons showed an LODP of about 40. The esters derived from native cellulose were recrystallized by heat treatment and then saponified into cellulose II. After hydrolysis, they showed an LODP of about 40 (200 A(2000A) in chain length), a meridional reflection showing a long period of about 200 A(2000A), and a particle-like fragment having a size of about 200 A(2000A). For native cellulose, after chemical and physical treatments, the LODP, the long period, and the fragment length all decreased stepwise and by the same amounts. The steps were an integral multiple of 200 A(2000A), which is the value of the crystallite length obtained for the native and all other celluloses. The results suggest that native cellulose has a periodic structure at intervals of 200 A(2000A) in length. 40 references, 14 figures, 5 tables.

  1. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.

    PubMed Central

    Rice, D; Barone, S

    2000-01-01

    Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes (i.e., proliferation, migration, differentiation, synaptogenesis, myelination, and apoptosis). Evidence from numerous sources demonstrates that neural development extends from the embryonic period through adolescence. In general, the sequence of events is comparable among species, although the time scales are considerably different. Developmental exposure of animals or humans to numerous agents (e.g., X-ray irradiation, methylazoxymethanol, ethanol, lead, methyl mercury, or chlorpyrifos) demonstrates that interference with one or more of these developmental processes can lead to developmental neurotoxicity. Different behavioral domains (e.g., sensory, motor, and various cognitive functions) are subserved by different brain areas. Although there are important differences between the rodent and human brain, analogous structures can be identified. Moreover, the ontogeny of specific behaviors can be used to draw inferences regarding the maturation of specific brain structures or neural circuits in rodents and primates, including humans. Furthermore, various clinical disorders in humans (e.g., schizophrenia, dyslexia, epilepsy, and autism) may also be the result of interference with normal ontogeny of developmental processes in the nervous system. Of critical concern is the possibility that developmental exposure to neurotoxicants may result in an acceleration of age-related decline in function. This concern is compounded by the fact that developmental neurotoxicity that results in small effects can have a profound societal impact when amortized across the entire population and across the life span of humans. Images Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 8 Figure 9 Figure 12 Figure 14 Figure 16 Figure 17 PMID:10852851

  2. Development of peatlands in northern Minnesota. Final report

    SciTech Connect

    Wright, H.E. Jr.; Glaser, P.H.; Janssens, J.A.

    1985-01-01

    Boreal peatlands are widely distributed across northern Minnesota, where they cover more than 20% of the regional landscape. A regional survey of these peatlands reveals a remarkable degree of uniformity among the vegetation assemblages and an exceptionally close relationship among the vegetation, water chemistry, water level, and presumed hydrology. These relationships are best integrated by the striking landform patterns that, from the air, resemble fluvial landforms such as islands, rivers, and ripple marks. The patterns instead indicate a sensitive adjustment of peat growth to local hydrology and water quality, making the landform patterns an exceptionally important tool for discerning the potential directions and controls on peatland development. A detailed investigation of the Red Lake peatland was undertaken to test a hypothesis on landform development based on an analysis of variations in the present-day landforms, vegetation, water chemistry, and inferred direction of water movement. The peat stratigraphy, based largely on an analysis of fossil bryophytes, indicates that the west-central watershed at Red Lake was overrum by an ombrotrophic bog forest approximately 2000 years ago, but that the forest was subsequently replaced by non-forested Sphagnum communities similar to the vegetation in the present-day bog drains and Sphagnum lawns. These results agree with the initial hypothesis. The stratigraphy indicates that the forested bog islands have expanded over the last 400 years, which indicates a more sensitive adjustment of the patterns to hydrological variations than predicted by the hypothesis. These results may be applicable to a much wider area because of the broad regional uniformity of the peatland patterns. 57 references, 14 figures, 6 tables.

  3. Late Triassic-Jurassic paleogeography and origin of Gulf of Mexico basin

    SciTech Connect

    Salvador, A.

    1987-04-01

    The basic structural and stratigraphic framework of the Gulf of Mexico Basin was established during the Late Triassic and the Jurassic. During the Late Triassic and Early Jurassic, as the North American plate started to separate from the South American and African plates, the area of the future basin was part of an extensive landmass broken by tensional grabens that were filled by red beds and volcanics. Marine deposition was restricted to embayments of the Pacific Ocean in northwestern and central Mexico. These marine embayments persisted during the early Middle Jurassic, but seawater did not reach the future Gulf of Mexico Basin until the Callovian. Widespread salt deposits known today from two separate areas of the basin resulted from this initial flooding. During the Late Jurassic, marine conditions progressively extended over increasingly larger parts of the Gulf of Mexico Basin. However, the basin was not connected to the Atlantic Ocean until late in the Jurassic. This paleogeographic reconstruction suggests that the Gulf of Mexico Basin formed as a result of the southward drift of the Yucatan continental block away from the remainder of the North American plate. The separation began in the Late Triassic, continued slowly and sporadically during the Early and Middle Jurassic, and quickened after the Middle Jurassic salt formed. As a result, the salt deposits were split into the two segments known today, and oceanic crust formed in the center of the basin. Early in the Late Jurassic, the Yucatan platform reached its present position and the Gulf of Mexico Basin was born. 14 figures.

  4. Frictional pressure drop in horizontal pneumatic conveying of coal and limestone

    SciTech Connect

    Daw, C.S.; Thomas, J.F.

    1983-08-01

    Pneumatic conveying experiments were conducted at Oak Ridge National Laboratory (ORNL) with crushed coal, limestone, and coal-limestone mixtures on a conveying system designed to represent the branch feed lines in the TVA 20-MW(e) atmospheric fluidized bed combustor. Test conditions were chosen to cover the anticipated operating ranges of the pilot plant. Details of the experimental apparatus and a summary of the results are presented in ORNL/TM-7724. This report is a further analysis of the horizontal pressure-drop data produced by the ORNL experiments. The results are compared with previous data and correlations in the literature, and the combined data provide strong evidence that there at least two possible pressure-drop modes in horizontal, dilute-phase conveying. The ORNL results follow a high-pressure-drop mode, while a major portion of data in the literature follow a low-pressure-drop mode. The results of Mehta (1955) and Peskin (1963) confirm the existence of the high-pressure-drop mode. It is proposed that the two pressure-drop modes result from inertia-dominated and viscous-dominated flow. With an inertial model, it is possible to derive an expression for the horizontal pressure drop that agrees remarkably well with the ORNL data, the larger-particle data of Mehta (1955), and the data of Peskin (1963). The small particle data of Mehta and the bulk of the data in the literature appear to follow the viscous flow model developed by Julian and Dukler (1965). It also appears that some data in the literature may represent combinations of the two flow regimes or transitions between them. 29 references, 15 figures, 2 tables.

  5. Slurry fired heater cold-flow modelling

    SciTech Connect

    Moujaes, S.F.

    1983-07-01

    This report summarizes the experimental and theoretical work leading to the scale-up of the SRC-I Demonstration Plant slurry fired heater. The scale-up involved a theoretical model using empirical relations in the derivation, and employed variables such as flow conditions, liquid viscosity, and slug frequency. Such variables have been shown to affect the heat transfer characteristics ofthe system. The model assumes that, if all other variables remain constant, the heat transfer coefficient can be scaled up proportional to D/sup -2/3/ (D = inside diameter of the fired heater tube). All flow conditions, liquid viscosities, and pipe inclinations relevant to the demonstration plant have indicated a slug flow regime in the slurry fired heater. The annular and stratified flow regimes should be avoided to minimize the potential for excessive pipe erosion and to decrease temperature gradients along the pipe cross section leading to coking and thermal stresses, respectively. Cold-flow studies in 3- and 6.75-in.-inside-diameter (ID) pipes were conducted to determine the effect of scale-up on flow regime, slug frequency, and slug dimensions. The developed model assumes that conduction heat transfer occurs through the liquid film surrounding the gas slug and laminar convective heat transfer to the liquid slug. A weighted average of these two heat transfer mechanisms gives a value for the average pipe heat transfer coefficient. The cold-flow work showed a decrease in the observed slug frequency between the 3- and 6.75-ID pipes. Data on the ratio of gas to liquid slug length in the 6.75-in. pipe are not yet complete, but are expected to yield generally lower values than those obtained in the 3-in. pipe; this will probably affect the scale-up to demonstration plant conditions. 5 references, 15 figures, 7 tables.

  6. Empirical characterization of oil-shale cratering experiments. [RDX, ANFO, PETN, TNT

    SciTech Connect

    Edwards, C.L.; Craig, J.L.; Lombardo, K.

    1983-01-01

    Numerous small- and intermediate-size cratering experiments have been conducted in Piceance Creek Basin oil shale at the Colony and Anvil Points oil shale mines near Rifle, Colorado. The purpose of these experiments was to evaluate scaling as a tool to infer the behavior of large-scale tests from small-scale experiments, to calibrate the hydrodynamic computer codes used to model explosive fragmentation of oil shale, and to investigate the influence of bedding plane orientation, natural joints, fractures, and the grade of oil shale on rock fragmentation. The small tests were made using PETN and RDX explosive with charge sizes of a few grams. The intermediate-sized tests used ANFO or TNT explosives with charge sizes of 5 to 100 kg. Crater dimensions were measured on all experiments. Crater volumes were calculated from screened rubble volumes on the intermediate-scale experiments and measured directly on the small-scale experiments. Fragment size distributions were measured on most of the intermediate-sized tests and on several of the small-scale experiments. The analyses of these cratering data show: (1) small-scale cratering tests can be used to qualitatively predict the kinds of geologic interactions that will influence a larger-scale experiment; (2) the site specific geology plays a dominant role in the formation of the crater; (3) small flaws and fractures influence crater development and particle size distributions in small-scale craters in the same manner that joint and fracture systems influence intermediate-scale experiments; (4) complex site geology causes increases in the critical and optimum depths of burial and changes the symmetry of the crater; and (5) small- and intermediate-scale cratering experiments can be used to calibrate hydrodynamic computer codes if great care is used to identify the effect of site specific geology. 15 figures, 6 tables.

  7. Oligocene volcanism and multiple caldera formation in the Chinati Mountains, Presidio County, Texas

    SciTech Connect

    Cepeda, J.C.; Henry, C.D.

    1983-01-01

    The Chinati Mountains caldera, which lies in Trans-Pecos Texas in the southern Basin and Range Province, was formed by eruption of the Mitchell Mesa Rhyolite. Volcanism in the Chinati Mountains area began several million years before formation of the Chinati Mountains caldera. Rocks of the Morita Ranch Formation, Infiernito caldera, and Shely Group ring the caldera on the south, east, and north. After its collapse, the caldera was filled by rhyolitic to trachytic lava flows and an ash-flow tuff of the Chinati Mountains Group. These include, from oldest to youngest, the lower trachyte, middle trachyte, lower rhyolite, upper trachyte, and upper rhyolite (ash-flow tuff). The Chinati Mountains Group was then intruded by the West Chinati Stock, the resurgent dome of the caldera. Three cycles of rhyolitic to trachytic magmatism, all derived from a zoned magma chamber, are represented by (1) Mitchell Mesa Rhyolite to lower and middle trachytes, (2) lower rhyolite to upper trachyte, and (3) upper rhyolite to West Chinati Stock. Dominant caldera collapse followed eruption of the Mitchell Mesa Rhyolite, but collapse is also associated with rhyolitic eruptions in the second and third cycles. The entire sequence erupted between 32 and 33 mya. The Chinati Mountains area is the site of one major, inactive silver mine and numerous prospects for silver, lead, zinc, copper, molybdenum, uranium, and fluorite. The Shafter silver district produced 31 million ounces of silver from Permian dolomitic limestones just south of the southern boundary of the caldera. Major prospects are associated with a quartz-monzonite porphyry intrusion (copper-molybdenum) just west of Shafter and with the West Chinati Stock (silver, lead, zinc, copper, and fluorite). All mineralization is probably genetically related to the caldera. 74 references, 15 figures, 3 tables.

  8. Facies and geologic history of an exposed Miocene rift-margin carbonate platform: Gulf of Suez, Egypt

    SciTech Connect

    James, N.P.; Coniglio, M.; Aissaoui, D.M.; Purser, B.H.

    1988-05-01

    Abu Shaar is a small exhumed carbonate platform of lower to middle Miocene age on a horst of Precambrian crystalline rock along the western side of the Gulf of Suez. The reef-rimmed complex is entirely dolomite but with exquisitely preserved primary and diagenetic microfabrics. Similar platforms, some of which contain hydrocarbons, are buried beneath evaporites in the Gulf. The platform developed in three stages, defined as local members of the Rudeis Formation. The first stage records deposition during progressive marine onlap as aprons of mixed terrigenous-carbonate sediments evolved into a wide reef-rimmed platform. Synsedimentary platform-margin collapse subsequently removed the most seaward portions of the reefs along the eastern Gulf-facing margin. These truncation surfaces were then covered by a second phase of reef growth and deposition of fore-reef carbonates. The third and final stage, deposited following a sea level drop and subaerial exposure, is a series of well-bedded peritidal carbonates that become progressively more evaporitic upward. Fore-reef facies are again truncated by synsedimentary slope failure. Former evaporites are now recorded as collapse breccias, contorted bedding, black chert nodules, and evaporite molds. Porosity is mainly secondary as vugs and molds and is highest in platform interior facies. These more porous sediments contained more aragonitic components originally and were less affected by submarine cementation. In contrast, the higher degree of synsedimentary lithification of platform-margin reef and fore-reef sediments is comparable with what is commonly observed in modern reef-dominated platform margins. 15 figures, 1 tables.

  9. Evaluation of the Malvern optical particle monitor. [Volumetric size distribution

    SciTech Connect

    Anderson, R. J.; Johnson, E.

    1983-07-01

    The Malvern 2200/3300 Particle Sizer is a laser-based optical particle sizing device which utilizes the principle of Fraunhofer Diffraction as the means of particle size measurement. The instrument is designed to analyze particle sizes in the range of 1 to 1800 microns diameter through a selection of lenses for the receiving optics. It is not a single-particle counter but rather an ensemble averager over the distribution of particles present in the measuring volume. Through appropriate measurement techniques, the instrument can measure the volumetric size distribution of: solids in gas or liquid suspension; liquid droplets in gas or other immiscible liquids; and, gas bubbles in liquid. (Malvern Handbook, Version 1.5). This report details a limited laboratory evaluation of the Malvern system to determine its operational characteristics, limitations, and accuracy. This investigation focused on relatively small particles in the range of 5 to 150 microns. Primarily, well characterized particles of coal in a coal and water mixture were utilized, but a selection of naturally occurring, industrially generated, and standard samples (i.e., glass beads) wer also tested. The characteristic size parameter from the Malvern system for each of these samples was compared with the results of a Coulter particle counter (Model TA II) analysis to determine the size measurement accuracy. Most of the particulate samples were suspended in a liquid media (water or isoton, plus a dispersant) for the size characterization. Specifically, the investigations contained in this report fall into four categories: (a) Sample-to-lense distance and sample concentration studies, (b) studies testing the applicability to aerosols, (c) tests of the manufacturer supplied software, and (d) size measurement comparisons with the results of Coulter analysis. 5 references, 15 figures, 2 tables.

  10. Occurrence of amitotic division of trophoblast cell nuclei in blastocysts of the western spotted skunk (Spilogale putorius latifrons).

    PubMed

    Isakova, Galina K; Mead, Rodney A

    2004-01-01

    A cytogenetic examination of spreaded cells of diapausing and early activated blastocysts obtained from 7 female western spotted skunks was performed. Mitosis was not observed in 1626 cells obtained from 9 diapausing blastocysts; however, 12 (1.5%) figures of diploid mitosis were seen in 851 cells from 5 early activated embryos. Diameter of the cell nuclei varied from 4 to 29 microm during diapause, and from 5 to 40 microm in activated blastocyst, and the heterogeneity in nuclear size was significantly different between diapausing and activated embryos (P<0.01). About 80% of nuclei from diapausing blastocysts measured 9 to 16 microm, whereas a similar percentage of nuclei from activated blastocysts ranged from 15 to 27 microm. Many enlarged nuclei exhibited morphological features characteristic of mammalian polytene (i.e. endopolyploid with polytenic organization of chromosomes) trophoblast cells. The number of silver stained nucleoli in all the nuclei did not exceed 2, which corresponds to the number of nucleolus organizers in the diploid karyotype in this species of skunk and suggests the polytene organization of chromosomes in enlarged nuclei. About 10% of large interphase nuclei were observed to undergo amitosis, i.e. direct division by constriction. The resulting nuclear fragments in diapausing blastocysts usually had normal morphology and active nucleoli. In activated embryos, nearly 15% of amitotically divided nuclei appeared to be dividing into fragments of unequal size, one of which had normal cell nuclear morphology and extremely large silver positive nucleoli, and the other fragment exhibited signs of cell death. We interpret these data as indicating that 1) amitotic division of trophoblast endopolyploid cell nuclei in the skunk blastocysts may generate new trophoblast cells which contribute to increased cell number during both diapause and activation stages, and 2) activation of blastocysts after diapause is related to the production of trophoblast cells with enhanced synthetic capabilities.

  11. Alteration of tissue disposition of cadmium by chelating agents. [Mice; rats

    SciTech Connect

    Klaassen, C.D.; Waalkes, M.P.; Cantilena, L.R. Jr.

    1984-03-01

    The effect of several chelating agents (diethyldithiocarbamic acid, DDC; nitrilotriacetic acid, NTA; 2,3-dimercaptopropanol, BAL; d,l-penicillamine, PEN; 2,3-dimercaptosuccinic acid, DMSA; ethylenediaminetetraacetic acid, EDTA; and diethylenetriaminepentaacetic acid, DTPA) on the toxicity, distribution and excretion of cadmium (Cd) was determined in mice. When chelators were administered immediately after Cd, significant increases in survival were noted after treatment with DMSA, EDTA, and DTPA. DTPA, followed by EDTA and then DMSA, were consistently the most effective in decreasing the tissue concentrations of Cd and increasing the excretion of Cd. NTA, BAL, DDC and PEN had no beneficial effects. To determine the role of MT in the acute decrease in chelator efficacy following Cd poisoning, rats were injected IV with Cd followed by DTPA at various times after Cd. Although DTPA reduced Cd content in the various organs when given immediately after Cd, the chelator was ineffective at all later times. Increases in hepatic and renal metallothionein (MT) did not occur until 2 hr after Cd, and did not coincide with the earlier drop in chelator efficacy. Blockade of MT synthesis by actinomycin D failed to eliminate this decreased DTPA effectiveness. Therefore, it appears that MT does not play an important role in the acute decrease in efficacy of chelation therapy for Cd poisoning. The effect of repeated daily administration of chelators on the distribution and excretion of Cd was studied by administering chelators daily for 5 days starting 48 hr after Cd. DTPA, EDTA, DMSA and BAL significantly increased the urinary elimination of Cd. Thus, mobilization of Cd into urine occurs with repeated chelation therapy, which may decrease tissue concentrations of Cd and reduce the toxicity of the metal. 4 references, 15 figures, 2 tables.

  12. Expanding the scope of lamellar keratoplasty.

    PubMed Central

    Rich, L F

    1999-01-01

    PURPOSE: To investigate whether applications of current technology, such as cryolathe and excimer laser, might improve outcomes and increase use of lamellar keratoplasty. METHODS: Six studies were performed, beginning with animals and progressing to human subjects. The first study compared cryolathed with hand-dissected rabbit corneas to ascertain which created a smoother donor interface. The second animal pilot study was done to determine whether thickness of donor cornea resection could be accurately predicted with the cryolathe. A prospective animal trial was then undertaken to compare lamellar keratoplasty outcomes using cryolathed versus hand-dissected tissue. The fourth work extrapolated previous animal findings to lamellar keratoplasty in human disease. Finally, two ongoing studies are described. The first explores the possibility of sutureless lamellar keratoplasty. The second utilizes the excimer laser to dissect the recipient stromal bed. RESULTS: The initial animal pilot study demonstrated a clearer stromal surface in cryolathed versus hand-dissected corneal tissue. The second pilot showed that plano-powered donor tissue could be generated to predetermined thickness. The prospective animal trial revealed that clear grafts of intended thickness could be obtained with cryolathing. Human studies suggested that lamellar keratoplasty using cryolathe-prepared donor tissue may offer superior results to free-hand dissection. Finally, one ongoing study indicates that sutureless lamellar keratoplasty is untenable, and the other shows that clear grafts can be obtained by combining cryolathed donor tissue with recipient photoablation. CONCLUSION: This body of work demonstrates that use of new lamellar keratoplasty technology may offer expanded scope and better outcomes than traditional lamellar keratoplasty techniques. Images FIGURE 1 FIGURE 3 FIGURE 4A FIGURE 4B FIGURE 8A FIGURE 8B FIGURE 9 FIGURE 10 FIGURE 10B FIGURE 11A FIGURE 11B FIGURE 12A FIGURE 12B FIGURE 13

  13. Experimental study of radiative pion capture on /sup 13/C, /sup 20/Ne, /sup 90/Zr, /sup 19/F and /sup 12/C

    SciTech Connect

    Martoff, C.J.

    1980-11-01

    Photon spectra for 50 < E/sub ..gamma../ < 135 MeV have been measured from the radiative capture of stopped negative pions by the nuclides /sup 13/C, /sup 19/F, /sup 20/Ne, and /sup 90/Zr. The e/sup +/e/sup -/ pair spectrometer system used has resolution 850 keV fwhm and photon detection efficiency 5 x 10/sup -6/. The total radiative capture branching ratios measured are /sup 13/C (1.66 +- 0.25)%, /sup 19/F (2.40 +- 0.48)%, /sup 20/Ne (1.60 +- 0.24)%, and /sup 90/Zr (2.1 +- 0.5)%. The partial radiative capture branching ratios to four bound states and two resonances in /sup 20/F, and two bound states and three resonances in /sup 13/B have also been measured. The branching ratio for /sup 13/C(..pi../sup -/,..gamma..)/sup 13/B g.s. is (6.1 +- 1.2) x 10/sup -4/. Comparison of this result with the beta decay rate of /sup 13/B shows that (84 +- 16)% of the pion capture amplitude is accounted for by the Gamow-Teller matrix element. Further analysis suggests that much of the remaining strength is E2. The measured branching ratios to resonant states in /sup 13/C(..pi../sup -/,..gamma..)/sup 13/B are shown to be in agreement with detailed shell model calculations. The total single-particle strength in these transitions is shown to be approximately half as large as that of the T = 3/2 part of the E1 photoresonance (the Giant Dipole Resonance) in /sup 13/C. The branching ratio for /sup 20/Ne(..pi../sup -/,..gamma..)/sup 20/F (T = 1, J/sup ..pi../ = 1/sup +/, E/sub x/ = 1.06 MeV) is 0.91 +- 0.52).10/sup -4/. Comparison with the electroexcitation of the analog giant M1 state in /sup 20/Ne (11.24 MeV) shows that the M1 transition amplitude is less than (46 +- 14)% Gamow-Teller. This result is in agreement with detailed shell model calculations of the M1 transition. The photon spectrum for radiative pion capture from flight (reaction /sup 12/C(..pi../sup +/ T = 44 MeV, ..gamma.. at 90/sup 0/)) has been measured. 13 figures, 12 tables.

  14. Comparative acute and subchronic toxicity of ethylene glycol monopropyl ether and ethylene glycol monopropyl ether acetate

    SciTech Connect

    Katz, G.V.; Krasavage, W.J.; Terhaar, C.J.

    1984-08-01

    The acute toxicity of ethylene glycol monopropyl ether (EGPE) and ethylene-glycol monopropyl ether acetate (EGPEA) was determined in a series of standardized tests. The oral LD/sub 50/ in rats was 3089 and 9456 mg/kg EGPE and EGPEA, respectively. Skin irritation was slight following an occluded single dose application of either compound to the guinea pig abdomen. The dermal LD/sub 50/ for guinea pigs was 1 to 5 mL/kg and greater than 20 mL/kg EGPE and EGPEA, respectively. EGPE produced a very weak positive sensitization response in one of five guinea pigs. EGPE produced transient moderate to severe eye irritation in rabbits while EGPEA produced slight eye irritation. Subchronic toxicity was determined in a series of oral and inhalation studies. Groups of 10 male rats were dosed with 15, 7.5, 3.75 or 1.88 mmole/kg EGPE and 30, 15, or 7.5 mmole/kg EGPEA by gavage 5 days/week for 6 weeks. Hemoglobinuria was seen at least once at all dose levels of both compounds. EGPE had little effect on feed consumption or body weight gain, while body weight gain was reduced in the two high dose groups exposed to EGPEA and feed consumption was reduced at all dose levels. Hematologic changes were seen at all dose levels of both compounds. Absolute and/or relative spleen weights were increased at all but the lowest EGPE dose level and at all EGPEA dose levels. Gross and histopathologic examinations revealed significant effects on the spleen of animals exposed to EGPE and on the spleen, liver, kidney, and testes of animals exposed to EGPEA. Groups of 10 rats (5 M, 5 F) were exposed to 800, 400, 200 or 100 ppm EGPE or EGPEA 6 hr/day, 5 days/week for a total of 11 exposures. Body weight gains in all exposure groups were comparable to controls. 13 references, 13 figures, 9 tables.

  15. Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

    PubMed Central

    Schaffner, T.; Taylor, K.; Bartucci, E. J.; Fischer-Dzoga, K.; Beeson, J. H.; Glagov, S.; Wissler, R. W.

    1980-01-01

    lysozyme or acid lipase activity. The occurrence of a population of cells with several functional and structural features of macrophages among the lipid-laden cells of experimental diet-induced arterial lesions suggests that some foam cells may be derived from monocytes. An alternative explanation, that metabolically altered autochthonous arterial wall cells assume one or more characteristics of mononuclear phagocytes is less likely, since some of the markers used in these experiments are unrelated. Both explanations deserve further careful study. Images Figure 1 Figure 2 Figure 3 Figures 4-7 Figures 8-11 Figure 12 Figure 13 Figures 14-16 PMID:6772035

  16. Lanthanide-amine template synthesis. Preparation and molecular structures of Ln(L) (CH/sub 3/CN) (CF/sub 3/SO/sub 3/)/sub 3/ (L = 1,9-Bis(2-aminoethyl)-1,4,6,9,12,14-hexaazacyclohexadecane; Ln = La, Yb) and La(en)/sub 4/(CH/sub 3/CN)(CF/sub 3/SO/sub 3/)/sub 3/

    SciTech Connect

    Smith, P.H.; Raymond, K.N.

    1985-10-09

    The title compounds have been prepared as part of a project to prepare kinetically inert macrocyclic amine complexes of the lanthanides in which the metal is surrounded by a covalently linked cage of amine ligating groups. The macrocycles are prepared in a reaction utilizing the metal ion as a template. The structures have been determined by single-crystal X-ray diffraction. The macrocyclic amine-lanthanide complexes have been prepared by the addition of bis(dimethylamino)methane to 1 equiv of lanthanide ion and 2 equiv of tren (N(CH/sub 2/CH/sub 2/NH/sub 2/)/sub 3/) in acetonitrile. The lanthanum complex (LaC/sub 19/H/sub 39/N/sub 9/O/sub 9/S/sub 3/F/sub 9/) prepared by this procedure is 10-coordinate with eight nitrogens from the macrocycle and two oxygens from two trifluoromethanesulfonate (triflate) anions. It crystallizes in space group P1 with Z = 2 and a = 10.716 (2) A, b = 13.733 (2) A, c = 14.211 (2) A, ..cap alpha.. = 98.87 (2)/sup 0/, ..beta.. = 97.54 (2)/sup 0/, and ..gamma.. = 107.45 (2)/sup 0/. The analogous ytterbium complex (YbC/sub 19/H/sub 39/N/sub 9/O/sub 9/S/sub 3/F/sub 9/) is 9-coordinate with one triflate oxygen and eight nitrogens from the macrocycle. It also crystallizes in space group P1 with Z = 2 and a = 9.594 (2) A, b = 10.940 (2) A, c = 18.072 (2) A, ..cap alpha.. = 74.07 (1)/sup 0/, ..beta.. = 74.70(1); and ..gamma.. = 81.90 (1)/sup 0/. The lanthanum-ethylenediamine complex (LaC/sub 13/H/sub 35/N/sub 9/O/sub 9/S/sub 3/F/sub 9/) is 9-coordinate with eight nitrogens from four ethylenediamines and one oxygen from a triflate anion and crystallizes in space group P1 with Z = 2 and a = 9.526 (2) A, b = 12.919 (2) A, c = 14.077 (2) A, ..cap alpha.. = 102.62 (1)/sup 0/, ..beta.. = 91.38 (l)/sup 0/, and ..gamma.. = 98.03 (1)/sup 0/. 14 references, 13 figures, 12 tables.

  17. Low-energy nuclear fusion data and their relation to magnetic and laser fusion

    SciTech Connect

    Jarmie, N.

    1980-04-01

    The accuracy of the basic fusion data for the T(d,n)/sup 4/He, /sup 3/He(d,p)/sup 4/He, T(t,2n)/sup 4/He, D(d,n)/sup 3/He, and D(d,p)T reactions was investigated in the 10- to 100-keV bombarding energy region, and the effects of inaccuracies on the design of fusion reactors were assessed. The data base for these reactions (particularly, the most critical T(d,n)/sup 4/He reaction) rests on 25-year-old experiments the accuracy (often assumed to be +- 5%) of which has rarely been questioned: yet, in all except the d + d reactions, there are significant differences among data sets. The errors in the basic data sets may be considerably larger than previously expected, and the effect on design calculations should be significant. Much of the trouble apparently lies in the accuracy of the energy measurements, which are difficult at low energies. Systematic errors of up to 50% are possible in the reactivity values of the present T(d,n)/sup 4/He data base. The errors in the reactivity will propagate proportionately into the errors in fusion probabilities in reactor calculations. /sup 3/He(d,p)/sup 4/He reaction cross sections could be in error by as much as 50% in the low-energy region. The D(d,n)/sup 3/He and D(d,p)T cross sections appear to be well known and consistent. The T(t,2n)/sup 4/He cross section is poorly known and may be subject to large systematic errors. Improved absolute measurements for all the reactions in the low bombarding energy region (10 to 100 keV) are needed, but until they are done, the data sets should be left as they are (except for T(t,2n)/sup 4/He data, which could be lowered by about 50%). The apparent uncertainties of these data sets should be kept in mind. 14 figures.

  18. The Geographic Distribution of Boulder Halo Craters at Mid-to-High Latitudes on Mars

    NASA Technical Reports Server (NTRS)

    Rader, L. X.; Fassett, C. I.; Levy, J. S.; King, I. R.; Chaffey, P. M.; Wagoner, C. M.; Hanlon, A. E.; Watters, J. L.; Kreslavsky, M. A.; Holt, J. W.; Dyar, M. D.

    2017-01-01

    Extensive evidence exists for ground ice at mid-to-high latitudes on Mars, including results from neutron spectroscopy [1-3], thermal properties [4-5], geomorphology [e.g., 6-9], and the in situ observations of Mars Phoenix [10]. This ground ice has been hypothesized to be emplaced diffusively and fill pores [11], or to have accumulated by ice and dust deposition that draped or mantled the terrain [7, 12]. These two processes are not mutually exclusive; both potentially have occurred on Mars [5]. One of the landforms found in areas where ground ice is common on Mars are boulder halo craters [e.g., 13-15] (Figure 1), which are topographically muted impact craters that are filled by ice-rich regolith. They are outlined by boulders that trace a circular outline of the original crater rim. Boulder halos generally have distinctly higher boulder densities than the surrounding background plains and have few boulders in their interiors. The mechanism of boulder halo crater formation is somewhat uncertain. Our working model is that an impact event occurs with sufficient size to excavate to a depth greater than the boulder-poor, ice-rich soils. Excavated boulders are deposited around the crater's rim and in its proximal ejecta. Quite rapidly [14], the crater becomes infilled by icy soil. Rather than being buried, boulders in the halo remain at the surface, perhaps be-cause they 'float' relative to finer-grained materials [14, 16]. Regardless of the details of this process, the life-time of boulders at the surface is much greater than the timescale needed to remove most of the craters' topography. Physical weathering of rocks must be greatly out-paced by crater infilling (the opposite of what is typical, e.g., on the Moon [17]). The rapidity of this infilling is easiest to understand if icy mantling material is deposited and accumulates, rather than simply being added by pore filling of soils. If this model is correct, boulder halos only form when they excavate rock

  19. Acquired color vision loss and a possible mechanism of ganglion cell death in glaucoma.

    PubMed Central

    Nork, T M

    2000-01-01

    FIGURE 4 FIGURE 5 FIGURE 8 FIGURE 9 FIGURE 10 FIGURE 11 FIGURE 15 FIGURE 16 FIGURE 18 FIGURE 20 FIGURE 21 FIGURE 22 PMID:11190032

  20. Retinal photic injury in normal and scorbutic monkeys.

    PubMed Central

    Tso, M O

    1987-01-01

    disruption of the blood-retinal barrier. The photo-oxidative reaction appears to linger, resulting in chronic retinal degeneration. It is hypothesized that in some forms of age-related macular degeneration, patients suffer from repeated mild photic insult throughout their lifetime. Aging has been associated with subclinical scurvy, which leads to even greater susceptibility to photic injury. Although ascorbate moderates many biochemical functions of the body and helps the retina ameliorate photo-oxidative injury, it should be regarded as a nutritional supplement to maintain health when consumed in appropriate amounts and not as a therapeutic agent for the treatment of severe insults. Images FIGURE 1 A FIGURE 1 B FIGURE 2 A FIGURE 2 B FIGURE 3 A FIGURE 3 B FIGURE 4 A FIGURE 4 B FIGURE 4 C FIGURE 4 D FIGURE 4 E FIGURE 5 A FIGURE 5 B FIGURE 5 C FIGURE 5 D FIGURE 5 E FIGURE 5 F FIGURE 6 A FIGURE 6 B FIGURE 7 A FIGURE 7 B FIGURE 7 C FIGURE 7 D FIGURE 7 E FIGURE 7 F FIGURE 8 A FIGURE 8 B FIGURE 8 C FIGURE 9 A FIGURE 9 B FIGURE 9 C FIGURE 9 D FIGURE 9 E FIGURE 9 F FIGURE 10 A FIGURE 10 B FIGURE 10 C FIGURE 10 D FIGURE 11 A FIGURE 11 B FIGURE 11 C FIGURE 11 D FIGURE 11 E FIGURE 11 F FIGURE 12 A FIGURE 12 B FIGURE 13 A FIGURE 13 B FIGURE 14 FIGURE 15 A FIGURE 15 B FIGURE 16 FIGURE 17 FIGURE 18 A FIGURE 18 B FIGURE 19 FIGURE 20 A FIGURE 20 B FIGURE 21 FIGURE 22 A FIGURE 22 B FIGURE 23 A FIGURE 23 B FIGURE 24 A FIGURE 24 B FIGURE 25 A FIGURE 25 B FIGURE 26 A FIGURE 26 B FIGURE 26 C FIGURE 26 D FIGURE 27 A FIGURE 27 B PMID:3447341

  1. The Pajarito Plateau: a bibliography

    USGS Publications Warehouse

    Mathien, Frances Joan; Steen, Charlie R.; Allen, Craig D.

    1993-01-01

    Pajarito Plateau is described as the high tableland that lies between the Jemez Mountains on the west and the Rio Grande on the east. From north to south, it extends from the Chama Valley to La Cañada de Cochiti (Hewett 1906:14)(Figure 1). Because human activity rarely stops at such definite boundaries, major ethnographic studies of Tewa (San Ildefonso and Santa Clara) and Keres (Cochiti) linguistic groups are included. (Even though most of the historic pueblos occupied by the Tewa and Keres are not located on the Pajarito Plateau, oral traditions and archaeological data suggest that these groups once occupied sites on the plateau.) Towa studies are not included because Steen believed Towa ancestors were not involved in major cultural developments of the Pajarito Plateau. In addition, a bibliography of the Jemez area (home of Towa people) has been prepared by Michael Elliott (1982) and included with his nomination of large Pueblo sites near Jemez Springs to the National Register of Historic Places that is on file at the Museum of New Mexico, Laboratory of Anthropology, in Santa Fe. Both Steen and Mathien included references to geographically and historically related material that does not focus on the Pajarito Plateau but, nonetheless, is important to understanding the area's archaeology and physical environment, for example, lithic resources available from Cerro Pedernal or in the Sangre de Cristo Mountains.

  2. FOREWORD: Heterogenous nucleation and microstructure formation—a scale- and system-bridging approach Heterogenous nucleation and microstructure formation—a scale- and system-bridging approach

    NASA Astrophysics Data System (ADS)

    Emmerich, H.

    2009-11-01

    in [8]. Furthermore, the honorable invitation to publish a special issue in Journal of Physics: Condensed Matter dedicated to the Priority Program's topic allows the obtained results to be communicated to relevant international colleagues, which stimulates further interest and encourages future collaborations. The issue comprises the research results of the participants during the first two year period of the Priority Program as well as that of the international referees of the program. Now, what precisely is the research concept of the Priority Program and thus, what are the articles in this special issue dedicated to? Ever since the pioneering work of Volmer and Weber [9], Becker and Döring [10] as well as Turnbull and Fisher [11] nucleation has been modelled more or less phenomenologically. These traditional models describe nucleation by stochastic processes of single atoms, respectively, molecules, which attach at primary droplets. Those thereby growing droplets become stable by reaching a critical size. This concept has largely been employed to model thermal activated first-order phase transformations. However it contains basic weak points, which raises the question of its physical justification. For instance, the dependence of the interfacial free energy on the critical size of a nucleus is—from the point of view of recent experiments—not considered adequately. In the past years, several advances have been performed to put the modelling of nucleation and microstructure formation on a wider base [12-15]. Figure 1 Figure 1. Illustration of the interdisciplinary approach in the Research Priority Program 'Nucleation and Growth Kinetics in Colloids and Metals—Steps towards a Scale- and System-Bridging Understanding' [8]: to advance towards a system- and scale-bridging detailed understanding of the energetics and kinetics of heterogeneous nucleation and micro-structure formation, two different experimental (binary colloids and binary metallic alloys) model