Science.gov

Sample records for 15-year time frame

  1. A 15-Year Time-series Study of Tooth Extraction in Brazil.

    PubMed

    Cunha, Maria Aparecida Goncalves de Melo; Lino, Patrícia Azevedo; Santos, Thiago Rezende Dos; Vasconcelos, Mara; Lucas, Simone Dutra; Abreu, Mauro Henrique Nogueira Guimarães de

    2015-11-01

    Tooth loss is considered to be a public health problem. Time-series studies that assess the influence of social conditions and access to health services on tooth loss are scarce.This study aimed to examine the time-series of permanent tooth extraction in Brazil between 1998 and 2012 and to compare these series in municipalities with different Human Development Index (HDI) scores and with different access to distinct primary and secondary care.The time-series study was performed between 1998 and 2012, using data from the Brazilian National Health Information System. Time-series study was performed between 1998 and 2012. Two annual rates of tooth extraction were calculated and evaluated separately according to 3 parameters: the HDI, the presence of a Dental Specialty Center, and coverage by Oral Health Teams. The time-series was analyzed using a linear regression model.An overall decrease in the tooth-loss tendencies during this period was observed, particularly in the tooth-extraction rate during primary care procedures. In the municipalities with an HDI that was lower than the median, the average tooth-loss rates were higher than in the municipalities with a higher HDI. The municipalities with lower rates of Oral Health Team coverage also showed lower extraction rates than the municipalities with higher coverage rates.In general, Brazil has shown a decrease in the trend to extract permanent teeth during these 15 years. Increased human development and access to dental services have influenced tooth-extraction rates.

  2. A 15-Year Time-series Study of Tooth Extraction in Brazil

    PubMed Central

    Cunha, Maria Aparecida Goncalves de Melo; Lino, Patrícia Azevedo; dos Santos, Thiago Rezende; Vasconcelos, Mara; Lucas, Simone Dutra; de Abreu, Mauro Henrique Nogueira Guimarães

    2015-01-01

    Abstract Tooth loss is considered to be a public health problem. Time-series studies that assess the influence of social conditions and access to health services on tooth loss are scarce. This study aimed to examine the time-series of permanent tooth extraction in Brazil between 1998 and 2012 and to compare these series in municipalities with different Human Development Index (HDI) scores and with different access to distinct primary and secondary care. The time-series study was performed between 1998 and 2012, using data from the Brazilian National Health Information System. Time-series study was performed between 1998 and 2012. Two annual rates of tooth extraction were calculated and evaluated separately according to 3 parameters: the HDI, the presence of a Dental Specialty Center, and coverage by Oral Health Teams. The time-series was analyzed using a linear regression model. An overall decrease in the tooth-loss tendencies during this period was observed, particularly in the tooth-extraction rate during primary care procedures. In the municipalities with an HDI that was lower than the median, the average tooth-loss rates were higher than in the municipalities with a higher HDI. The municipalities with lower rates of Oral Health Team coverage also showed lower extraction rates than the municipalities with higher coverage rates. In general, Brazil has shown a decrease in the trend to extract permanent teeth during these 15 years. Increased human development and access to dental services have influenced tooth-extraction rates. PMID:26632688

  3. Solid-state framing camera with multiple time frames

    SciTech Connect

    Baker, K. L.; Stewart, R. E.; Steele, P. T.; Vernon, S. P.; Hsing, W. W.; Remington, B. A.

    2013-10-07

    A high speed solid-state framing camera has been developed which can operate over a wide range of photon energies. This camera measures the two-dimensional spatial profile of the flux incident on a cadmium selenide semiconductor at multiple times. This multi-frame camera has been tested at 3.1 eV and 4.5 keV. The framing camera currently records two frames with a temporal separation between the frames of 5 ps but this separation can be varied between hundreds of femtoseconds up to nanoseconds and the number of frames can be increased by angularly multiplexing the probe beam onto the cadmium selenide semiconductor.

  4. Reflections, 15 Years Later

    ERIC Educational Resources Information Center

    Knox, George

    2016-01-01

    George Knox reflects on his 15-year career as president of Labette Community College in Parsons, Kansas. Knox writes that, as a first-time president coming into a brand new system, he was very fortunate to have many seasoned presidents and mentors in Kansas and from the American Association of Community Colleges' (AACC) Presidents Academy. He says…

  5. 10 CFR 710.35 - Time frames.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Time frames. 710.35 Section 710.35 Energy DEPARTMENT OF... Matter or Special Nuclear Material Miscellaneous § 710.35 Time frames. Statements of time established for processing aspects of a case under this subpart are the agency's desired time frames in implementing...

  6. 10 CFR 710.35 - Time frames.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Time frames. 710.35 Section 710.35 Energy DEPARTMENT OF... Matter or Special Nuclear Material Miscellaneous § 710.35 Time frames. Statements of time established for processing aspects of a case under this subpart are the agency's desired time frames in implementing...

  7. 10 CFR 710.35 - Time frames.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Time frames. 710.35 Section 710.35 Energy DEPARTMENT OF... Matter or Special Nuclear Material Miscellaneous § 710.35 Time frames. Statements of time established for processing aspects of a case under this subpart are the agency's desired time frames in implementing...

  8. Maternal Jail Time, Conviction, and Arrest as Predictors of Children's 15-Year Antisocial Outcomes in the Context of a Nurse Home Visiting Program

    ERIC Educational Resources Information Center

    Shlafer, Rebecca J.; Poehlmann, Julie; Donelan-McCall, Nancy

    2012-01-01

    Data from the Nurse-Family Partnership intervention program were analyzed to compare the "selection" versus "unique" effects of maternal jail time on adolescent antisocial and health risk outcomes. Data from 320 women and their firstborn children were available from the prenatal, birth, and 15-year assessments. Consistent with a selection…

  9. Time evolution of an SLR reference frame

    NASA Astrophysics Data System (ADS)

    Angermann, D.; Gerstl, M.; Kelm, R.; Müller, H.; Seemüller, W.; Vei, M.

    2002-07-01

    On the basis of LAGEOS-1 and LAGEOS-2 data we computed a 10-years (1990-2000) solution for SLR station positions and velocities. The paper describes the data processing with the DGFI software package DOGS. We present results for station coordinates and their time variation for 41 stations of the global SLR network, and discuss the stability and time evolution of the SLR reference frame established in the same way. We applied different methods to assess the quality and consistency of the SLR results. The results presented in this paper include: (1) a time series of weekly estimated station coordinates; (2) a comparison of a 10-year LAGEOS-1 and LAGEOS-2 solution; (3) a comparison of 2.5-year solutions with the combined 10-year solution to assess the internal stability and the time evolution of the SLR reference frame; (4) a comparison of the SLR reference frame with ITRF97; and (5) a comparison of SLR station velocities with those of ITRF97 and NNR NUVEL-1A.

  10. Outside School Time: An Examination of Science Achievement and Non-Cognitive Characteristics of 15-Year Olds in Several Countries

    ERIC Educational Resources Information Center

    Suter, Larry E.

    2016-01-01

    Elementary and secondary students spend more hours outside of class than in formal school and thus have more time for interaction with everyday science. However, evidence from a large international survey, Program of International Student Assessment (PISA) (OECD 2012), found a negative relationship between number of hours attending after-school…

  11. Time reversibility in the quantum frame

    SciTech Connect

    Masot-Conde, Fátima

    2014-12-04

    Classic Mechanics and Electromagnetism, conventionally taken as time-reversible, share the same concept of motion (either of mass or charge) as the basis of the time reversibility in their own fields. This paper focuses on the relationship between mobile geometry and motion reversibility. The goal is to extrapolate the conclusions to the quantum frame, where matter and radiation behave just as elementary mobiles. The possibility that the asymmetry of Time (Time’s arrow) is an effect of a fundamental quantum asymmetry of elementary particles, turns out to be a consequence of the discussion.

  12. 28 CFR 570.21 - Time-frames.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Time-frames. 570.21 Section 570.21... PROGRAMS Pre-Release Community Confinement § 570.21 Time-frames. (a) Community confinement. Inmates may be... inmate's term of imprisonment or six months. (c) Exceeding time-frames. These time-frames may be...

  13. 28 CFR 570.21 - Time-frames.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Time-frames. 570.21 Section 570.21... PROGRAMS Pre-Release Community Confinement § 570.21 Time-frames. (a) Community confinement. Inmates may be... inmate's term of imprisonment or six months. (c) Exceeding time-frames. These time-frames may be...

  14. 28 CFR 570.21 - Time-frames.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Time-frames. 570.21 Section 570.21... PROGRAMS Pre-Release Community Confinement § 570.21 Time-frames. (a) Community confinement. Inmates may be... inmate's term of imprisonment or six months. (c) Exceeding time-frames. These time-frames may be...

  15. 28 CFR 570.21 - Time-frames.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Time-frames. 570.21 Section 570.21... PROGRAMS Pre-Release Community Confinement § 570.21 Time-frames. (a) Community confinement. Inmates may be... inmate's term of imprisonment or six months. (c) Exceeding time-frames. These time-frames may be...

  16. Outside school time: an examination of science achievement and non-cognitive characteristics of 15-year olds in several countries

    NASA Astrophysics Data System (ADS)

    Suter, Larry E.

    2016-03-01

    Elementary and secondary students spend more hours outside of class than in formal school and thus have more time for interaction with everyday science. However, evidence from a large international survey, Program of International Student Assessment (PISA) (OECD 2012), found a negative relationship between number of hours attending after-school science and science assessment scores in many countries, raising questions about why. The secondary analysis of the 2006, 2009, and 2012 PISA surveys found that in most Western countries the longer students attended after-school science programs (in a typical week), the lower their PISA standardized science test score, but the higher their positive attitudes toward future science careers, interest in science, and self-confidence in science. Several potential hypotheses for this relationship are examined and rejected. Further analysis of a causal relationship between frequent attendance in after-school programs and student achievement and attitudes should clearly identify the content of the program so that the analysis could distinguish experiences closely related to regular school curricula from the informal science activities that are not. A new analysis also should include carefully designed longitudinal surveys to test the effectiveness of informal experiences on later life choices in career and study. Revision of a Paper prepared for AERA meetings in Chicago, 19 April 2015.

  17. Variability of OH rotational temperatures on time scales from hours to 15 years by kinetic temperature variations, emission layer changes, and non-LTE effects

    NASA Astrophysics Data System (ADS)

    Noll, Stefan

    2016-07-01

    Rotational temperatures derived from hydroxyl (OH) line emission are frequently used to study atmospheric temperatures at altitudes of about 87 km. While the measurement only requires intensities of a few bright lines of an OH band, the interpretation can be complicated. Ground-based temperatures are averages for the entire, typically 8 km wide emission layer. Variations in the rotational temperature are then caused by changes of the kinetic temperature and the OH emission profile. The latter can also be accompanied by differences in the layer-averaged efficiency of the thermalisation of the OH rotational level populations. Since this especially depends on the frequency of collisions with O_2, which is low at high altitudes, the non-local thermodynamic equilibrium (non-LTE) contribution to the measured temperatures can be significant and variable. In order to understand the impact of the different sources of OH rotational temperature variations from time scales of hours to a solar cycle, we have studied spectra from the astronomical echelle spectrographs X-shooter and UVES located at Cerro Paranal in Chile. While the X-shooter data spanning 3.5 years allowed us to measure temperatures for 25 OH and two O_2 bands, the UVES spectra cover no more than 10 OH bands simultaneously but a period of about 15 years. These data have been complemented by kinetic temperature and OH and O_2 emission profiles from the multi-channel radiometer SABER on the TIMED satellite. Taking the O_2 and SABER kinetic temperatures as reference and considering the different band-dependent emission profiles, we could evaluate the contribution of non-LTE effects to the measured OH rotational temperatures depending on line set, band, and time. Non-LTE contributions are significant for most bands and can exceed 10 K. The amplitudes of their average nocturnal and seasonal variation are of the order of 1 to 2 K.

  18. 15 years of SO2 measurements at Popocatépetl volcano: from individual COSPEC measurements to real-time mini-DOAS-network measurements

    NASA Astrophysics Data System (ADS)

    Delgado Granados, Hugo; Cárdenas González, Lucio; Alvarez Nieves, José Manuel

    2010-05-01

    On December 21, 1994, Popocatépetl Volcano (PV) started to erupt explosively with a series of vulcanian-type events with large emissions of gas. The activity remained explosive along 1995 with a period of quiescence from August 1995 to early March 1996. On March 5, 1996 the volcano resumed the eruptive activity (vulcanian in nature) and on March 25 the eruptive style changed to effusive. The first lava dome was partially destroyed on April 30, 1996. Up to 2001, at least 12 lava domes were extruded and destroyed. Until December 2009, PV continues producing lava domes, and destroying them with vulcanian explosions. Here, a summary of the SO2 emissions at PV during the last 15 years is presented. Work on PV's gas emissions started in early 1994. Initially, on February 1st 1994, SO2 emissions were 16 kg/s measured with a correlation spectrometer (COSPEC). Gas emissions prior to the eruption were of a magmatic signature, and with a similar order-of-magnitude as emissions during the first year of eruption (10s-100s kg/ s). The values during the period between August 1995 and early March 1996 were ~9 kg/s in average (maximum of ~19 kg/s, and a minimum of ~1 kg/s). After 1996 the order-of-magnitude raised to an average of ~130 kg/s. SO2 emissions have had a high variability through time the maximum value was measured on December 13, 2000 (~2000 kg/s). Within the framework of the NOVAC (Network for the Observation of Volcanic and Atmospheric Change) project 4 mini-DOAS instruments have been deployed at PV, all stations acquire spectra in real-time and send the data to the receiving station at CENAPRED in Mexico City where data is collected for immediate evaluation of the volcanic activity. Automatically, data is also sent to a server in Chalmers University for archiving and other uses. Data is post-processed at CENAPRED and UNAM and a database is being built since 2005. These measurements allow to estimate SO2 emissions in real-time and in a more accurate way. The network

  19. The effects of the framing of time on delay discounting.

    PubMed

    DeHart, William Brady; Odum, Amy L

    2015-01-01

    We examined the effects of the framing of time on delay discounting. Delay discounting is the process by which delayed outcomes are devalued as a function of time. Time in a titrating delay discounting task is often framed in calendar units (e.g., as 1 week, 1 month, etc.). When time is framed as a specific date, delayed outcomes are discounted less compared to the calendar format. Other forms of framing time; however, have not been explored. All participants completed a titrating calendar unit delay-discounting task for money. Participants were also assigned to one of two delay discounting tasks: time as dates (e.g., June 1st, 2015) or time in units of days (e.g., 5000 days), using the same delay distribution as the calendar delay-discounting task. Time framed as dates resulted in less discounting compared to the calendar method, whereas time framed as days resulted in greater discounting compared to the calendar method. The hyperboloid model fit best compared to the hyperbola and exponential models. How time is framed may alter how participants attend to the delays as well as how the delayed outcome is valued. Altering how time is framed may serve to improve adherence to goals with delayed outcomes.

  20. Time and Outcome Framing in Intertemporal Tradeoffs

    ERIC Educational Resources Information Center

    Scholten, Marc; Read, Daniel

    2013-01-01

    A robust anomaly in intertemporal choice is the delay-speedup asymmetry: Receipts are discounted more, and payments are discounted less, when delayed than when expedited over the same interval. We developed 2 versions of the tradeoff model (Scholten & Read, 2010) to address such situations, in which an outcome is expected at a given time but…

  1. Reducing video frame rate increases remote optimal focus time

    NASA Technical Reports Server (NTRS)

    Haines, Richard F.

    1993-01-01

    Twelve observers made best optical focus adjustments to a microscope whose high-resolution pattern was video monitored and displayed first on a National Television System Committee (NTSC) analog color monitor and second on a digitally compressed computer monitor screen at frame rates ranging (in six steps) from 1.5 to 30 frames per second (fps). This was done to determine whether reducing the frame rate affects the image focus. Reducing frame rate has been shown to be an effective and acceptable means of reducing transmission bandwidth of dynamic video imagery sent from Space Station Freedom (SSF) to ground scientists. Three responses were recorded per trial: time to complete the focus adjustment, number of changes of focus direction, and subjective rating of final image quality. It was found that: the average time to complete the focus setting increases from 4.5 sec at 30 fps to 7.9 sec at 1.5 fps (statistical probability = 1.2 x 10(exp -7)); there is no significant difference in the number of changes in the direction of focus adjustment across these frame rates; and there is no significant change in subjectively determined final image quality across these frame rates. These data can be used to help pre-plan future remote optical-focus operations on SSF.

  2. Time pressure increases cooperation in competitively framed social dilemmas.

    PubMed

    Cone, Jeremy; Rand, David G

    2014-01-01

    What makes people willing to pay costs to benefit others? Does such cooperation require effortful self-control, or do automatic, intuitive processes favor cooperation? Time pressure has been shown to increase cooperative behavior in Public Goods Games, implying a predisposition towards cooperation. Consistent with the hypothesis that this predisposition results from the fact that cooperation is typically advantageous outside the lab, it has further been shown that the time pressure effect is undermined by prior experience playing lab games (where selfishness is the more advantageous strategy). Furthermore, a recent study found that time pressure increases cooperation even in a game framed as a competition, suggesting that the time pressure effect is not the result of social norm compliance. Here, we successfully replicate these findings, again observing a positive effect of time pressure on cooperation in a competitively framed game, but not when using the standard cooperative framing. These results suggest that participants' intuitions favor cooperation rather than norm compliance, and also that simply changing the framing of the Public Goods Game is enough to make it appear novel to participants and thus to restore the time pressure effect. PMID:25551386

  3. 12 CFR 1805.503 - Time frame for raising match.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Time frame for raising match. 1805.503 Section 1805.503 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS PROGRAM Matching Funds Requirements § 1805.503...

  4. Framing health messages based on anomalies in time preference.

    PubMed

    Ortendahl, Monica; Fries, James F

    2005-08-01

    Time discounting processes and their effects are increasingly taken into account in health-related decisions. Because these effects have a potentially large impact the characteristics of discounting should also be taken into consideration when framing health messages. Research on the relationship between time and health is discussed with a special focus on discounting biases. The criteria for selection of articles were potential practical application when formulating health messages. Time discounting processes vary with individuals and contexts. Therefore, no single model is expected to describe discounting processes completely. Discounting biases appear more prevalent in health decisions than in economic decisions, even when health and monetary outcomes are matched for utility. Research on decision-making under conditions of uncertainty has documented numerous anomalies of expected utility. Analysis on the anomalies related to intertemporal choice and discounted utility (DU) include the magnitude effect, dynamic inconsistency effect, instant endowment, status quo bias, and sequence effect. Discounting biases in the formulation of preventive health messages are important. The desire for behavioral change in these programs would benefit from considering the psychological factor of discounting. Framing health messages in terms of large, important outcomes or long delays should induce lower implicit discount rates. Framing health messages as losses rather than gains, or as involving a series of outcomes rather than individual outcomes, might similarly lower the implicit discount rate used.

  5. Stability of Gabor Frames Under Small Time Hamiltonian Evolutions

    NASA Astrophysics Data System (ADS)

    de Gosson, Maurice A.; Gröchenig, Karlheinz; Romero, José Luis

    2016-06-01

    We consider Hamiltonian deformations of Gabor systems, where the window evolves according to the action of a Schrödinger propagator and the phase-space nodes evolve according to the corresponding Hamiltonian flow. We prove the stability of the frame property for small times and Hamiltonians consisting of a quadratic polynomial plus a potential in the Sjöstrand class with bounded second-order derivatives. This answers a question raised in de Gosson (Appl Comput Harmonic Anal 38(2):196-221, 2015)

  6. Realization of fertility intentions by different time frames.

    PubMed

    Dommermuth, Lars; Klobas, Jane; Lappegård, Trude

    2015-06-01

    This paper focuses on the realization of positive fertility intentions with different time frames. The analyses are based on a unique combination of survey data and information from Norwegian administrative registers on childbearing in the years following the complete selected sample. Guided by the theoretical and empirical framework of the Theory of Planned Behavior (TPB), the results suggest that a fertility intention's time frame is relevant for childbearing behaviour, but the patterns are somewhat different for respondents who were childless at the time of the interview compared to those who already had children. Overall, childless were less likely to realize their fertility intentions than parents. Following the TPB, childless may underestimate the difficulty of acting on their intentions and therefore have more difficulty realizing their intentions, versus parents who take into account their ability to manage another child. The results also show that childless with an immediate fertility intention are more likely to succeed than those with a longer-term intention. Likewise, parents with an immediate fertility intention are more likely to realize their intention during the two first years after the interview, but after four years the childbearing rate was higher among those with longer-term fertility intentions. PMID:26047988

  7. 42 CFR 405.950 - Time frame for making a redetermination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Time frame for making a redetermination. 405.950....950 Time frame for making a redetermination. (a) General rule. The contractor mails, or otherwise... decision-making time frame begins on the date the contractor receives the late-filed request...

  8. 42 CFR 405.950 - Time frame for making a redetermination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Time frame for making a redetermination. 405.950....950 Time frame for making a redetermination. (a) General rule. The contractor mails, or otherwise... decision-making time frame begins on the date the contractor receives the late-filed request...

  9. 42 CFR 405.950 - Time frame for making a redetermination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 2 2013-10-01 2013-10-01 false Time frame for making a redetermination. 405.950....950 Time frame for making a redetermination. (a) General rule. The contractor mails, or otherwise... decision-making time frame begins on the date the contractor receives the late-filed request...

  10. 42 CFR 405.950 - Time frame for making a redetermination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 2 2012-10-01 2012-10-01 false Time frame for making a redetermination. 405.950....950 Time frame for making a redetermination. (a) General rule. The contractor mails, or otherwise... decision-making time frame begins on the date the contractor receives the late-filed request...

  11. Hydrofluoric acid burns: a 15-year experience.

    PubMed

    Stuke, Lance E; Arnoldo, Brett D; Hunt, John L; Purdue, Gary F

    2008-01-01

    Hydrofluoric acid (HF) is a strong inorganic acid commonly used in many domestic and industrial settings. It is one of the most common chemical burns encountered in a burn center and frequently engenders controversy in its management. We report our 15 year experience with management of HF burns. We reviewed our experience from 1990 to 2005 for patients admitted with HF burns. Primary treatment was with calcium gluconate gel. Arterial infusion of calcium and fingernail removal were reserved for unrelenting symptoms. There were 7944 acute burn admissions to our center during this study period, 204 of which were chemical burns. HF burns comprised 17% of these chemical burn admissions (35 patients). All were men, with a mean burn size of 2.1 +/- 1.5% (range, 1-6%) and hospital stay of 1.6 +/- 0.7 days (range, 0-3 days). The most common seasonal time of injury was in the summer. Twelve patients (34%) were admitted to the intensive care unit for a total of 14 intensive care unit days, primarily for arterial infusions. Ventilator support was not required in any patient. No electrolyte abnormalities occurred. All burns were either partial thickness or small full thickness with no operative intervention required and no deaths. The upper extremity was most commonly involved (29 patients, 83%). The most common cause was air conditioner cleaner (8 patients, 23%). HF is a common cause of chemical burns. Although hospital admission is usually required for vigorous treatment and pain control, burn size is usually small and does not cause electrolyte abnormalities, significant morbidity, or death. PMID:18849854

  12. 39 CFR 775.12 - Time frames for environmental impact statement actions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Time frames for environmental impact statement... NATIONAL ENVIRONMENTAL POLICY ACT PROCEDURES § 775.12 Time frames for environmental impact statement... environmental impact statements received in that office during the preceding week. The minimum time periods...

  13. 39 CFR 775.12 - Time frames for environmental impact statement actions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Time frames for environmental impact statement... NATIONAL ENVIRONMENTAL POLICY ACT PROCEDURES § 775.12 Time frames for environmental impact statement... environmental impact statements received in that office during the preceding week. The minimum time periods...

  14. 39 CFR 775.12 - Time frames for environmental impact statement actions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Time frames for environmental impact statement... NATIONAL ENVIRONMENTAL POLICY ACT PROCEDURES § 775.12 Time frames for environmental impact statement... environmental impact statements received in that office during the preceding week. The minimum time periods...

  15. 39 CFR 775.12 - Time frames for environmental impact statement actions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Time frames for environmental impact statement... NATIONAL ENVIRONMENTAL POLICY ACT PROCEDURES § 775.12 Time frames for environmental impact statement... environmental impact statements received in that office during the preceding week. The minimum time periods...

  16. 39 CFR 775.12 - Time frames for environmental impact statement actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Time frames for environmental impact statement... NATIONAL ENVIRONMENTAL POLICY ACT PROCEDURES § 775.12 Time frames for environmental impact statement... environmental impact statements received in that office during the preceding week. The minimum time periods...

  17. 42 CFR 403.251 - Loss ratio date and time frame provisions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Loss ratio date and time frame provisions. 403.251... Certification Program: Loss Ratio Provisions § 403.251 Loss ratio date and time frame provisions. (a) Initial... procedure that provides for the impact of a variety of factors, such as lapse of policies) for loss...

  18. 42 CFR 403.251 - Loss ratio date and time frame provisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Loss ratio date and time frame provisions. 403.251... Certification Program: Loss Ratio Provisions § 403.251 Loss ratio date and time frame provisions. (a) Initial... procedure that provides for the impact of a variety of factors, such as lapse of policies) for loss...

  19. 20 CFR 10.336 - What are the time frames for submitting bills?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false What are the time frames for submitting bills...' COMPENSATION ACT, AS AMENDED Medical and Related Benefits Medical Bills § 10.336 What are the time frames for submitting bills? To be considered for payment, bills must be submitted by the end of the calendar year...

  20. 20 CFR 10.336 - What are the time frames for submitting bills?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true What are the time frames for submitting bills...' COMPENSATION ACT, AS AMENDED Medical and Related Benefits Medical Bills § 10.336 What are the time frames for submitting bills? To be considered for payment, bills must be submitted by the end of the calendar year...

  1. 20 CFR 10.336 - What are the time frames for submitting bills?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false What are the time frames for submitting bills...' COMPENSATION ACT, AS AMENDED Medical and Related Benefits Medical Bills § 10.336 What are the time frames for submitting bills? To be considered for payment, bills must be submitted by the end of the calendar year...

  2. 20 CFR 30.421 - What are the time frames for submitting bills and reimbursement requests?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false What are the time frames for submitting bills... AMENDED Medical and Related Benefits Medical Bills § 30.421 What are the time frames for submitting bills and reimbursement requests? To be considered for payment, bills and reimbursement requests must...

  3. 20 CFR 30.421 - What are the time frames for submitting bills and reimbursement requests?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true What are the time frames for submitting bills... AMENDED Medical and Related Benefits Medical Bills § 30.421 What are the time frames for submitting bills and reimbursement requests? To be considered for payment, bills and reimbursement requests must...

  4. 20 CFR 30.421 - What are the time frames for submitting bills and reimbursement requests?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true What are the time frames for submitting bills... AMENDED Medical and Related Benefits Medical Bills § 30.421 What are the time frames for submitting bills and reimbursement requests? To be considered for payment, bills and reimbursement requests must...

  5. 20 CFR 10.336 - What are the time frames for submitting bills?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true What are the time frames for submitting bills...' COMPENSATION ACT, AS AMENDED Medical and Related Benefits Medical Bills § 10.336 What are the time frames for submitting bills? To be considered for payment, bills must be submitted by the end of the calendar year...

  6. 20 CFR 30.421 - What are the time frames for submitting bills and reimbursement requests?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false What are the time frames for submitting bills... AMENDED Medical and Related Benefits Medical Bills § 30.421 What are the time frames for submitting bills and reimbursement requests? To be considered for payment, bills and reimbursement requests must...

  7. 20 CFR 30.421 - What are the time frames for submitting bills and reimbursement requests?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false What are the time frames for submitting bills... AMENDED Medical and Related Benefits Medical Bills § 30.421 What are the time frames for submitting bills and reimbursement requests? To be considered for payment, bills and reimbursement requests must...

  8. 20 CFR 10.336 - What are the time frames for submitting bills?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false What are the time frames for submitting bills...' COMPENSATION ACT, AS AMENDED Medical and Related Benefits Medical Bills § 10.336 What are the time frames for submitting bills? To be considered for payment, bills must be submitted by the end of the calendar year...

  9. 21 CFR 814.40 - Time frames for reviewing a PMA.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Time frames for reviewing a PMA. 814.40 Section 814.40 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.40 Time frames...

  10. 21 CFR 814.40 - Time frames for reviewing a PMA.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Time frames for reviewing a PMA. 814.40 Section 814.40 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.40 Time frames...

  11. 21 CFR 814.40 - Time frames for reviewing a PMA.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Time frames for reviewing a PMA. 814.40 Section 814.40 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.40 Time frames...

  12. 21 CFR 814.40 - Time frames for reviewing a PMA.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Time frames for reviewing a PMA. 814.40 Section...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.40 Time frames for reviewing a PMA. Within 180 days after receipt of an application that is accepted for filing and to...

  13. 21 CFR 814.40 - Time frames for reviewing a PMA.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Time frames for reviewing a PMA. 814.40 Section...) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES FDA Action on a PMA § 814.40 Time frames for reviewing a PMA. Within 180 days after receipt of an application that is accepted for filing and to...

  14. Effects of Time Frame on the Recall Reliability of CFS Symptoms.

    PubMed

    Evans, Meredyth; Jason, Leonard A

    2015-09-01

    This study serves as an investigation of the reliability of symptom data as reported by individuals with chronic fatigue syndrome (CFS), across three recall time frames (the past week, the past month, and the past 6 months), and at two assessment points (with 1 week in between each assessment). Multilevel model analyses were used to determine the optimal recall time frame, in terms of test -retest reliability, for each of the Fukuda et al. (1994) case defining symptoms. Results suggested that the optimal time frame for reliably reporting CFS symptoms was six months for sore throat, lymph node pain, muscle pain, post-exertional malaise, headaches, memory/concentration difficulties, and unrefreshing sleep. For joint pain, the optimal time frame was one month. Researchers who are interested in the assessment of CFS symptoms need to take recall time frame into account, especially when the intended goal is to standardize and improve the methods used to reliably and accurately diagnose this complex illness.

  15. Prognosis after myocardial infarction: results of 15 year follow up.

    PubMed Central

    Merrilees, M A; Scott, P J; Norris, R M

    1984-01-01

    A total of 271 out of 757 patients who had suffered a myocardial infarction during 1966-7 were still alive after six years; these patients were subsequently followed up 15 years after the infarction. Two hundred and sixty eight (99%) of the patients alive at six years and 519 (95%) of the 549 originally discharged from hospital were traced. A coronary prognostic index, which had predicted survival both to three years and from three to six years after recovery from the infarct also predicted survival from six to 15 years after recovery. The major factor affecting survival to 15 years was age at the time of the original infarct. Among patients aged under 60 at the time of infarction women fared better than men (p = 0.027). Factors in the coronary prognostic index that were associated with impairment of left ventricular function at the time of infarction and that had predicted mortality to three years and from three to six years also predicted mortality from six to 15 years. These factors were cardiac enlargement, pulmonary venous congestion, and the presence of infarction before the index infarct. The dominant cause of death remained coronary heart disease and its complications. PMID:6229313

  16. Examining the Variability of Wind Power Output in the Regulation Time Frame: Preprint

    SciTech Connect

    Hodge, B. M.; Shedd, S.; Florita, A.

    2012-08-01

    This work examines the distribution of changes in wind power for different time scales in the regulation time frame as well as the correlation of changes in power output for individual wind turbines in a wind plant.

  17. Time frames and the distinction between affective and cognitive well-being.

    PubMed

    Luhmann, Maike; Hawkley, Louise C; Eid, Michael; Cacioppo, John T

    2012-08-01

    We examined whether the empirical differences between affective well-being (AWB) and cognitive well-being (CWB) might be due to (a) the use of different time frames in measures of AWB and CWB or (b) structural differences. In Study 1, a multitrait-multimethod (MTMM) analysis indicated that levels of different components are more similar but do not converge completely when the same time frame is used. In Study 2, we found that people are more likely to consider global life circumstances (as opposed to specific events and activities) when they evaluate their CWB, regardless of the specific time frame. In both studies, the time frame did not moderate the associations between AWB and CWB and important correlates (personality, life circumstances).

  18. Transformation from proper time on earth to coordinate time in solar system barycentric space-time frame of reference

    NASA Technical Reports Server (NTRS)

    Moyer, T. D.

    1976-01-01

    An expression was derived for the time transformation t - tau, where t is coordinate time in the solar system barycentric space-time frame of reference and tau is proper time obtained from a fixed atomic clock on earth. This transformation is suitable for use in the computation of high-precision earth-based range and Doppler observables of a spacecraft or celestial body located anywhere in the solar system; it can also be used in obtaining computed values of very long baseline interferometry data types. The formulation for computing range and Doppler observables, which is an explicit function of the transformation t - tau, is described briefly.

  19. PHENIX: Beyond 15 years of discovery

    SciTech Connect

    Morrison, David; Nagle, James L.

    2015-01-12

    The PHENIX experiment at BNL’s Relativistic Heavy Ion Collider (RHIC) was designed to uncover properties of the quark–gluon plasma (QGP) via rare penetrating probes. Over the past 15 years, the collaboration has delivered on its promised measurements, often with exciting results beyond those originally foreseen. That the QGP behaves as a nearly perfect fluid and that non-photonic electrons are substantially suppressed has led to the use of heavy quarks as probes of the medium. The PHENIX silicon vertex detectors are opening a new arena for QGP studies, and the MPC-EX, a novel forward calorimeter with silicon readout, accesses low-x physics via direct photons with unprecedented precision. PHENIX has proposed sPHENIX, a major upgrade using the recently acquired BaBar solenoid and full calorimetric coverage and high rate capabilities. sPHENIX will reconstruct jets and extend observables to higher transverse momentum, where comparisons to results from the Large Hadron Collider (LHC) heavy-ion program will provide the most insightful. Following the RHIC program, the nuclear physics community has identified an electron ion collider (EIC) as crucial to the next generation of QCD investigations. The BaBar magnet and sPHENIX calorimetry will be an excellent foundation for a new collaborative pursuit of discovery.

  20. PHENIX: Beyond 15 years of discovery

    DOE PAGES

    Morrison, David; Nagle, James L.

    2015-01-12

    The PHENIX experiment at BNL’s Relativistic Heavy Ion Collider (RHIC) was designed to uncover properties of the quark–gluon plasma (QGP) via rare penetrating probes. Over the past 15 years, the collaboration has delivered on its promised measurements, often with exciting results beyond those originally foreseen. That the QGP behaves as a nearly perfect fluid and that non-photonic electrons are substantially suppressed has led to the use of heavy quarks as probes of the medium. The PHENIX silicon vertex detectors are opening a new arena for QGP studies, and the MPC-EX, a novel forward calorimeter with silicon readout, accesses low-x physicsmore » via direct photons with unprecedented precision. PHENIX has proposed sPHENIX, a major upgrade using the recently acquired BaBar solenoid and full calorimetric coverage and high rate capabilities. sPHENIX will reconstruct jets and extend observables to higher transverse momentum, where comparisons to results from the Large Hadron Collider (LHC) heavy-ion program will provide the most insightful. Following the RHIC program, the nuclear physics community has identified an electron ion collider (EIC) as crucial to the next generation of QCD investigations. The BaBar magnet and sPHENIX calorimetry will be an excellent foundation for a new collaborative pursuit of discovery.« less

  1. Neonatal Duodenal Obstruction: A 15-Year Experience

    PubMed Central

    Rattan, Kamal Nain; Singh, Jasbir; Dalal, Poonam

    2016-01-01

    Background: Congenital duodenal obstruction is one of the commonest causes of neonatal intestinal obstruction. We are presenting our 15-year experience by analyzing clinical spectrum and outcome in neonates with duodenal obstruction admitted at our center. Material and Methods: The hospital records of all neonates admitted with duodenal obstruction from June 2000 to June 2015 were reviewed. The patient records were analyzed for antenatal diagnosis, age, sex, clinical presentation, diagnosis, associated anomalies, surgical procedures performed; postoperative morbidity and mortality. We excluded from our study malrotation of gut associated with congenital diaphragmatic hernia and abdominal wall defects. Results: A total of 81 patients were admitted, out of which 56 were males and 25 were females. Polyhydramnios was detected in 24 (30%) pregnancies. Average birth weight was 2.1±1.0Kg and average gestational age was 38 (SD±1) weeks with 17 (21%) preterm neonates. Presenting features were vomiting in 81(100%) which was bilious in 81% and non-bilious in 19%, epigastric fullness in 56 (69%) and dehydration in 18 (22%) and failure to thrive in 16 (19%). Most common cause of obstruction was duodenal atresia in 38 (46.9%), followed by malrotation of gut in 33 (40.7%), and annular pancreas in 4 cases. Depending upon site of location, infra-ampullary obstruction was the most common in 64 (79%), supra-ampullary in 9 (7.4%) and ampullary 8 neonates. Both duodenal atresia and malrotation of gut was present in 4 cases. X-ray abdomen was most commonly used investigation to confirm the diagnosis. All cases were managed surgically by open laparotomy. Eleven (13.5%) patients died due to sepsis and associated congenital anomalies. Conclusion: Congenital duodenal obstruction most commonly presents in early neonatal period with features of upper GIT obstruction like vomiting and epigastrium fullness as in our series. Early antenatal diagnosis and surgical interventions hold the key in

  2. A Possible Approach to Inclusion of Space and Time in Frame Fields of Quantum Representations of Real and Complex Numbers

    DOE PAGES

    Benioff, Paul

    2009-01-01

    Tmore » his work is based on the field of reference frames based on quantum representations of real and complex numbers described in other work. Here frame domains are expanded to include space and time lattices. Strings of qukits are described as hybrid systems as they are both mathematical and physical systems. As mathematical systems they represent numbers. As physical systems in each frame the strings have a discrete Schrodinger dynamics on the lattices.he frame field has an iterative structure such that the contents of a stage j frame have images in a stage j - 1 (parent) frame. A discussion of parent frame images includes the proposal that points of stage j frame lattices have images as hybrid systems in parent frames.he resulting association of energy with images of lattice point locations, as hybrid systems states, is discussed. Representations and images of other physical systems in the different frames are also described.« less

  3. Measuring dwell time percentage from head-mounted eye-tracking data--comparison of a frame-by-frame and a fixation-by-fixation analysis.

    PubMed

    Vansteenkiste, Pieter; Cardon, Greet; Philippaerts, Renaat; Lenoir, Matthieu

    2015-01-01

    Although analysing software for eye-tracking data has significantly improved in the past decades, the analysis of gaze behaviour recorded with head-mounted devices is still challenging and time-consuming. Therefore, new methods have to be tested to reduce the analysis workload while maintaining accuracy and reliability. In this article, dwell time percentages to six areas of interest (AOIs), of six participants cycling on four different roads, were analysed both frame-by-frame and in a 'fixation-by-fixation' manner. The fixation-based method is similar to the classic frame-by-frame method but instead of assigning frames, fixations are assigned to one of the AOIs. Although some considerable differences were found between the two methods, a Pearson correlation of 0.930 points out a good validity of the fixation-by-fixation method. For the analysis of gaze behaviour over an extended period of time, the fixation-based approach is a valuable and time-saving alternative for the classic frame-by-frame analysis. PMID:25529829

  4. An LCD driver with on-chip frame buffer and 3 times image compression

    NASA Astrophysics Data System (ADS)

    Sung, Star; Baudia, Jacques

    2008-01-01

    An LCD Driver with on-chip frame buffer and 3 times image compression codec reaching visually lossless image quality is presented. The frame buffer compression codec can encode and decode up to eight pixels in one clock cycle. Integrating a whole frame buffer with RGB=888 bits into the display driver sharply reduces power dissipated between the IO pad and PCB board at a cost of 50% IC die area increase. The existing working chip (STE2102, a ram-less LCD Driver with die size of 170mm x 12mm) is manufactured by ST Micro 0.18μm high voltage CMOS process. A new chip design with on-chip frame buffer SRAM and 3 times compression codec supporting QVGA (320x240) is completed which reduces the frame buffer SRAM density and area by a factor of ~3.0 times and cuts the power consumption of the on-chip SRAM frame buffer by ~9.0 times of which 3 times is contributed by less capacitive bit line load and another 3 times from data rate reduction from image compression. The compression codec having 25K gates in encoder and 10K in decoder accepts both YUV and RGB color formats. An on-chip color-space-conversion unit converts the decompressed YUV components with 420, 422 and 444 formats to be RGB format before driving out to be displayed. The high image quality is achieved by applying some patented proprietary compression algorithms including accurate prediction in DPCM, a Golomb-Rice like VLC coding with accurate predictive divider and an intelligent bit rate distribution control.

  5. KALREF—A Kalman filter and time series approach to the International Terrestrial Reference Frame realization

    NASA Astrophysics Data System (ADS)

    Wu, Xiaoping; Abbondanza, Claudio; Altamimi, Zuheir; Chin, T. Mike; Collilieux, Xavier; Gross, Richard S.; Heflin, Michael B.; Jiang, Yan; Parker, Jay W.

    2015-05-01

    The current International Terrestrial Reference Frame is based on a piecewise linear site motion model and realized by reference epoch coordinates and velocities for a global set of stations. Although linear motions due to tectonic plates and glacial isostatic adjustment dominate geodetic signals, at today's millimeter precisions, nonlinear motions due to earthquakes, volcanic activities, ice mass losses, sea level rise, hydrological changes, and other processes become significant. Monitoring these (sometimes rapid) changes desires consistent and precise realization of the terrestrial reference frame (TRF) quasi-instantaneously. Here, we use a Kalman filter and smoother approach to combine time series from four space geodetic techniques to realize an experimental TRF through weekly time series of geocentric coordinates. In addition to secular, periodic, and stochastic components for station coordinates, the Kalman filter state variables also include daily Earth orientation parameters and transformation parameters from input data frames to the combined TRF. Local tie measurements among colocated stations are used at their known or nominal epochs of observation, with comotion constraints applied to almost all colocated stations. The filter/smoother approach unifies different geodetic time series in a single geocentric frame. Fragmented and multitechnique tracking records at colocation sites are bridged together to form longer and coherent motion time series. While the time series approach to TRF reflects the reality of a changing Earth more closely than the linear approximation model, the filter/smoother is computationally powerful and flexible to facilitate incorporation of other data types and more advanced characterization of stochastic behavior of geodetic time series.

  6. 42 CFR 457.1160 - Program specific review process: Time frames.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... process: Time frames. (a) Eligibility or enrollment matter. A State must complete the review of a matter... services matter. The State must ensure that reviews are completed in accordance with the medical needs of... HUMAN SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS...

  7. An Agenda-Setting Time-Frame for the Civil Rights Issue, 1954-1976.

    ERIC Educational Resources Information Center

    Winter, James P.; Eyal, Chaim H.

    The role that time frame plays in the media agenda-setting process was studied by examining the single issue of civil rights over an extended period between 1954 and 1976. The public agenda was determined from 27 Gallup polls, conducted between 1954 and 1976, which asked respondents what they considered the most important issue facing the American…

  8. 42 CFR 457.1160 - Program specific review process: Time frames.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... process: Time frames. (a) Eligibility or enrollment matter. A State must complete the review of a matter... services matter. The State must ensure that reviews are completed in accordance with the medical needs of... HUMAN SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS...

  9. A population study of 5 to 15 year olds: full time maternal employment not associated with high BMI. The importance of screen-based activity, reading for pleasure and sleep duration in children's BMI.

    PubMed

    Taylor, Anne W; Winefield, Helen; Kettler, Lisa; Roberts, Rachel; Gill, Tiffany K

    2012-04-01

    To describe the relationship between maternal full time employment and health-related and demographic variables associated with children aged 5-15 years, and the factors associated with child overweight/obesity. Data from a chronic disease and risk factor surveillance system were limited to children aged 5-15 years whose mothers responded on their behalf (n = 641). Univariate/multivariate analyses described the differences between mothers who did and did not work full time. The same data were analysed comparing children who are overweight/obese against those with a normal BMI. The children of mothers who worked full time are more likely to be older, live in a household with a higher household income, be an only child or have one sibling or other child in the household, have a sole mother family structure and not spend any time reading for pleasure. No relationship was found between maternal employment and BMI. Compared with children of normal weight, those who were overweight/obese were more likely to spend no time studying, spend more than 2 h per day in screen-based activity and sleep less than 10 h per night. Child BMI status was not related to maternal employment. Although this analysis included eight diet related variables none proved to be significant in the final models.This study has shown that mothers' working status is not related to children's BMI. The relationship between overweight/obesity of children and high levels of screen-based activity, low levels of studying, and short sleep duration suggests a need for better knowledge and understanding of sedentary behaviours of children.

  10. Design and implementation of timing generator of frame transfer area-array CCD camera

    NASA Astrophysics Data System (ADS)

    Zhou, Jian-kang; Chen, Xin-hua; Zhou, Wang; Shen, Wei-min

    2008-03-01

    Frame transfer area-array CCD camera is the perfect solution for high-end real-time medical, scientific and industrial applications because it has characteristics of high fill factor, low dark current, high resolving power, high sensitivity, high linear dynamic range and electronic shutter capability. Time sequences of frame transfer area-array CCD camera have two compact segments: CCD driving sequences and CCD signal processing sequences. Proper working of CCD sensor lies on good driving sequences while accurate CCD signal processing sequences ensures high quality of CCD image. The relationship among CCD camera time sequences is complex and precise. The conventional methods are uneasy to implement time sequences of Frame transfer area-array CCD. Embedded designing method is introduced in this paper and field programmable gate array device is chosen as the hardware design platform. Phase-locked loops are used for precise phase shifting and embedded logic analyzer for waveform verification. CCD driving clocks, electronic shutter signal, A/D and black pixels clamp clocks and double correlation sampling clocks have been attained on the hardware platform and this timing generator can control exposure time flexibly. High quality images have been acquired through using this timing generator on the CCD circuit system board which has been designed by our team.

  11. LCFM - LIVING COLOR FRAME MAKER: PC GRAPHICS GENERATION AND MANAGEMENT TOOL FOR REAL-TIME APPLICATIONS

    NASA Technical Reports Server (NTRS)

    Truong, L. V.

    1994-01-01

    Computer graphics are often applied for better understanding and interpretation of data under observation. These graphics become more complicated when animation is required during "run-time", as found in many typical modern artificial intelligence and expert systems. Living Color Frame Maker is a solution to many of these real-time graphics problems. Living Color Frame Maker (LCFM) is a graphics generation and management tool for IBM or IBM compatible personal computers. To eliminate graphics programming, the graphic designer can use LCFM to generate computer graphics frames. The graphical frames are then saved as text files, in a readable and disclosed format, which can be easily accessed and manipulated by user programs for a wide range of "real-time" visual information applications. For example, LCFM can be implemented in a frame-based expert system for visual aids in management of systems. For monitoring, diagnosis, and/or controlling purposes, circuit or systems diagrams can be brought to "life" by using designated video colors and intensities to symbolize the status of hardware components (via real-time feedback from sensors). Thus status of the system itself can be displayed. The Living Color Frame Maker is user friendly with graphical interfaces, and provides on-line help instructions. All options are executed using mouse commands and are displayed on a single menu for fast and easy operation. LCFM is written in C++ using the Borland C++ 2.0 compiler for IBM PC series computers and compatible computers running MS-DOS. The program requires a mouse and an EGA/VGA display. A minimum of 77K of RAM is also required for execution. The documentation is provided in electronic form on the distribution medium in WordPerfect format. A sample MS-DOS executable is provided on the distribution medium. The standard distribution medium for this program is one 5.25 inch 360K MS-DOS format diskette. The contents of the diskette are compressed using the PKWARE archiving tools

  12. Decisions, decisions: analysis of age, cohort, and time of testing on framing of risky decision options.

    PubMed

    Mayhorn, Christopher B; Fisk, Arthur D; Whittle, Justin D

    2002-01-01

    Decision making in uncertain environments is a daily challenge faced by adults of all ages. Framing decision options as either gains or losses is a common method of altering decision-making behavior. In the experiment reported here, benchmark decision-making data collected in the 1970s by Tversky and Kahneman (1981, 1988) were compared with data collected from current samples of young and older adults to determine whether behavior was consistent across time. Although differences did emerge between the benchmark and the present samples, the effect of framing on decision behavior was relatively stable. The present findings suggest that adults of all ages are susceptible to framing effects. Results also indicated that apparent age differences might be better explained by an analysis of cohort and time-of-testing effects. Actual or potential applications of this research include an understanding of how framing might influence the decision-making behavior of people of all ages in a number of applied contexts, such as product warning interactions and medical decision scenarios.

  13. Efficient Time Frame Building for Online Data Reconstruction in ALICE Experiment

    NASA Astrophysics Data System (ADS)

    Rybalchenko, A.; Al-Turany, M.; Kouzinopoulos, C.; Winckler, N.

    2015-12-01

    After the Long Shutdown 2 period, the upgraded ALICE detector at the LHC will produce more than a terabyte of data per second. The data, constituted from a continuous un-triggered stream data, have to be distributed from about 250 First Level Processor nodes (FLPs) to about 1500 Event Processing Nodes (EPNs). Each FLP receives a small subset of the detector data that is chopped in sub-time frames. One EPN needs all the fragments from the 250 FLPs to build a full time frame. An algorithm has been implemented on the FLPs with the aim of optimizing the usage of the network connecting the FLPs and EPNs. The algorithm minimizes contention when several FLPs are sending to the same EPN. An adequate traffic shaping is implemented by delaying the sending time of each FLP by a unique offset. The payloads are stored in a buffer large enough to accommodate the delay provoked by the maximum number of FLPs. As the buffers are queued for sending, the FLPs can operate with the highest efficiency. Using the time information embedded in the data any further FLP synchronization can be avoided. Moreover, zero-copy and multipart messages of ZeroMQ are used to create full time frames on the EPNs without the overhead of copying the payloads. The concept and the performance measurement of the implementation on a reference computing cluster are presented.

  14. Construal level theory and theory of planned behavior: time frame effects on salient belief generation.

    PubMed

    Lutchyn, Yuliya; Yzer, Marco

    2011-07-01

    This study tests implications of different time specifications in behavioral definitions as used in belief-elicitation research. Using construal level theory and the theory of planned behavior as complementary frameworks, the authors examined temporal frame effects on beliefs about eating fruits and vegetables and beliefs about condom use generated in a belief-elicitation study. Consistent with propositions from construal level theory, the authors found that temporal perspective (performing the behavior tomorrow, in 3 months, in 6 months, or in 5 years) affects the type of salient behavioral beliefs, such that individuals generate more feasibility (efficacy) beliefs when thinking about proximal behaviors, but more desirability (attitudinal and normative) beliefs when the behavior in question is distal. The authors' results indicate the importance of time frame in behavioral definitions in belief-elicitation research.

  15. Quantum frames

    NASA Astrophysics Data System (ADS)

    Brown, Matthew J.

    2014-02-01

    The framework of quantum frames can help unravel some of the interpretive difficulties i the foundation of quantum mechanics. In this paper, I begin by tracing the origins of this concept in Bohr's discussion of quantum theory and his theory of complementarity. Engaging with various interpreters and followers of Bohr, I argue that the correct account of quantum frames must be extended beyond literal space-time reference frames to frames defined by relations between a quantum system and the exosystem or external physical frame, of which measurement contexts are a particularly important example. This approach provides superior solutions to key EPR-type measurement and locality paradoxes.

  16. Does the time frame between exercise influence the effectiveness of hydrotherapy for recovery?

    PubMed

    Halson, Shona L

    2011-06-01

    An increase in research investigating recovery strategies has occurred alongside the increase in usage of recovery by elite athletes. Because there is inconsistent evidence regarding the benefits of recovery on performance, it is necessary to examine research design to identify possible strategies that enhance performance in different athlete settings. The purpose of this review is to examine available recovery literature specifically related to the time frame between performance assessments to identify considerations for both research design and practical use of recovery techniques.

  17. Analysis of data systems requirements for global crop production forecasting in the 1985 time frame

    NASA Technical Reports Server (NTRS)

    Downs, S. W.; Larsen, P. A.; Gerstner, D. A.

    1978-01-01

    Data systems concepts that would be needed to implement the objective of the global crop production forecasting in an orderly transition from experimental to operational status in the 1985 time frame were examined. Information needs of users were converted into data system requirements, and the influence of these requirements on the formulation of a conceptual data system was analyzed. Any potential problem areas in meeting these data system requirements were identified in an iterative process.

  18. U.S. energy independence in 15 years

    SciTech Connect

    Rose, Chris R

    2008-01-01

    Establish U.S. energy independence within 15 years -- This is a enormous systems engineering challenge to thoroughly analyze the present mix of power generation, energy consumption in all sectors such as transportation, industrial, commercial and residential, and devise new technologies to assist the process to independence. At this level, all citizens will be affected, requiring not only effective technologies, but superior cost/benefit ratios and effective free market interactions. With U.S. energy independence, world markets will be influenced. It will be necessary to develop or modify new energy sources, possibly including storage, and adjust or modify energy consumption profiles. Figure 1 shows the expected transition from present-day energy consumption based on both domestic and imported energy. During the 15 year period, the U.S. transitions to energy independence, eliminating imports, and perhaps reduces total energy consumption due to increased efficiency. In the future, U.S. energy consumption is able to grow in accordance with national policies and enhanced domestic capabilities. At the present time, the primary energy import is hydrocarbon products -- primarily oil. Of that imported oil, most of it is used for transportation. In order to reduce the need for imported oil, the U.S. will need to revamp its energy supply and energy consumption mixes. This change in business and usage in the U.S. will require enonnous effort on the part of many organizations and individuals. Los Alamos National Laboratory (LANL) will take the technological lead on this grand challenge. Nearly all directorates, technical, planning and policy capabilities will be brought together and focused on this objective. A simplified chart of the interactions within LANL is shown in Figure 3. Given the enonnous undertaking of U.S. energy independence, the vast engineering, technological and science-based capabilities of LANL will work together performing systems engineering, applied

  19. Intelligent real-time CCD data processing system based on variable frame rate

    NASA Astrophysics Data System (ADS)

    Chen, Su-ting

    2009-07-01

    In order to meet the need of image shooting with CCD in unmanned aerial vehicles, a real-time high resolution CCD data processing system based on variable frame rate is designed. The system is consisted of three modules: CCD control module, data processing module and data display module. In the CCD control module, real-time flight parameters (e.g. flight height, velocity and longitude) should be received from GPS through UART (Universal Asynchronous Receiver Transmitter) and according to the corresponding flight parameters, the variable frame rate is calculated. Based on the calculated variable frame rate, CCD external synchronization control impulse signal is generated in the control of FPGA and then CCD data is read out. In the data processing module, data segmentation is designed to extract ROI (region of interest), whose resolution is equal to valid data resolution of HDTV standard conforming to SMPTE (1080i). On one hand, Ping-pong SRAM storage controller is designed in FPGA to real-time store ROI data. On the other hand, according to the need of intelligent observing, changeable window position is designed, and a flexible area of interest is obtained. In the real-time display module, a special video encoder is used to accomplish data format conversion. Data after storage is packeted to HDTV format by creating corresponding format information in FPGA. Through inner register configuration, high definition video analog signal is implemented. The entire system has been implemented in FPGA and validated. It has been used in various real-time CCD data processing situations.

  20. Talocalcaneal coalition in a 15 year old female basketball player.

    PubMed

    Schenkel, David; Degraauw, Jennifer; Degraauw, Christopher

    2010-12-01

    This case reports an adolescent athlete with activity related chronic bilateral dorsal foot pain and stiffness. A 15 year old competitive female basketball player presented to a chiropractor subsequent to an unsuccessful course of conservative treatment for posterior tibial dysfunction. The patient's plain films were incorrectly read as normal and a CT scan obtained by the radiologist called the findings bilateral osteoarthritis. The patient was awaiting a referral to a rheumatologist at the time of initial consultation with the chiropractor. Examination revealed limited subtalar mobility and review of the images revealed bilateral non-osseous talocalcaneal coalition. The patient was subsequently directed to a pediatric orthopedic surgeon and is scheduled for a resection of the coalition. Primary care practitioners should be aware of this uncommon, but not rare, variable clinical presentation as misdiagnosis and mismanagement could lead to suboptimal patient outcomes. To our knowledge this is the first case report of a patient with tarsal coalition published in chiropractic literature. In addition, this case is the first to report radiographic evidence of chronic mechanical stress to the second metatarsal associated with tarsal coalition.

  1. SLR Station Recovery, Center of Frame Motion, and Time Varying Gravity

    NASA Technical Reports Server (NTRS)

    Zelensky, Nikita P.; Lemoine, Frank G.; Chinn, Douglas S.; Melachroinos, Stavros; Wiser Beall, Jennifer; Larson, Jordan D.

    2012-01-01

    Weekly station position estimates, beginning with 1993, are derived from the ITRF2008-based SLR processing of up to four satellites: Lageos 1, Lageos2, Starlette, and Stella. Helmert parameters obtained from c omparison of weekly SLR station positions and the a-priori SLRF2008 station complement are evaluated for geocenter motion and scale. Two me thods for modeling time varying gravity are employed in the SLR satel lite POD processing, with GGM03S serving as the static gravity field. Both methods forward model atmosphere gravity derived from 6-hour ECM WF pressure data. The standard approach applies an annual 20x20 field estimated from 4 years of GRACE data, and the IERS2003 recommended linear rates for C20, C30, C40, C21, and S21. The alternate approach us es a new set of low-order/degree 4x4 coefficients estimated weekly fr om SLR & DORIS processing to 10 satellites from 1993-2012. This exper imental tvg4x4 model has been shown to improve the TOPEX, Jason-1, and Jason-2 altimeter satellite orbits,. In this paper we apply the more detailed time-variable gravity modeling to the SLR satellite POD pro cessing and subsequent reference frame analyses. For this study we will evaluate the orbit differences (periodic and secular) for the satel lites concerned, characterize the impact on the station coordinate solutions, and the impact on reference frame parameters (geocenter and s cale).

  2. Nature, nurture, or that fast food hamburger: media framing of diabetes in the New York Times from 2000 to 2010.

    PubMed

    Stefanik-Sidener, Kelsey

    2013-01-01

    Diabetes is a growing yet misunderstood health concern in the United States. This study examined the ways in which diabetes has been framed by the New York Times over the past decade. The public's perception of the causes and solutions to complex problems such as diabetes has significant implications for the way public policy interventions are viewed; therefore, understanding how diabetes is being framed in the media can be an important first step in shifting public opinion about ways to combat the disease. A content analysis of 239 articles published in the New York Times between 2000 and 2010 revealed that nearly one-third of articles failed to differentiate between type 1, type 2, and gestational diabetes, which may cause confusion given substantial differences in the root cause and treatment of each. An examination of frames used within each type of diabetes showed that the overall dominant frame across types was either a medical frame or a behavioral frame, with deficient use of a societal frame. The limited use of societal-level framing may make it difficult for the public to see the wider consequences of diabetes and decreases the likelihood of public support for policy solutions to combat the disease.

  3. Putting language back in the body: speech and gesture on three time frames.

    PubMed

    Kelly, Spencer D; Iverson, Jana M; Terranova, Joseph; Niego, Julia; Hopkins, Michael; Goldsmith, Leslie

    2002-01-01

    This article investigates the role that nonverbal actions play in language processing over 3 different time frames. First, we speculate that nonverbal actions played a role in how formal language systems emerged from our primate ancestors over evolutionary time. Next, we hypothesize that if nonverbal behaviors played a foundational role in the emergence of language over evolution, these actions should influence how children learn language in the present. Finally, we argue that nonverbal actions continue to play a role for adults in the moment-to-moment processing of language. Throughout, we take an embodied view of language and argue that the neural, cognitive, and social components of language processing are firmly grounded in bodily action. PMID:12405508

  4. Evaluating the Human Damage of Tsunami at Each Time Frame in Aggregate Units Based on GPS data

    NASA Astrophysics Data System (ADS)

    Ogawa, Y.; Akiyama, Y.; Kanasugi, H.; Shibasaki, R.; Kaneda, H.

    2016-06-01

    Assessments of the human damage caused by the tsunami are required in order to consider disaster prevention at such a regional level. Hence, there is an increasing need for the assessments of human damage caused by earthquakes. However, damage assessments in japan currently usually rely on static population distribution data, such as statistical night time population data obtained from national census surveys. Therefore, human damage estimation that take into consideration time frames have not been assessed yet. With these backgrounds, the objectives of this study are: to develop a method for estimating the population distribution of the for each time frame, based on location positioning data observed with mass GPS loggers of mobile phones, to use a evacuation and casualties models for evaluating human damage due to the tsunami, and evaluate each time frame by using the data developed in the first objective, and 3) to discuss the factors which cause the differences in human damage for each time frame. By visualizing the results, we clarified the differences in damage depending on time frame, day and area. As this study enables us to assess damage for any time frame in and high resolution, it will be useful to consider provision for various situations when an earthquake may hit, such as during commuting hours or working hours and week day or holiday.

  5. Side oblique real-time orthophotography with the 9Kx9K digital framing camera

    NASA Astrophysics Data System (ADS)

    Gorin, Brian A.

    2003-08-01

    BAE SYSTEMS has reported on a new framing camera incorporating an ultra high resolution CCD detector array comprised of 9,216 x 9,216 pixels fabricated on one silicon wafer. The detector array features a 1:2 frame-per-second readout capable of stereo imagery with Nyquist resolution of 57 lp/mm from high velocity, low altitude (V/H) airborne platforms. Flight tests demonstrated the capability of the focal plane electronics for differential image motion compensation (IMC) with Nyquist performance utilizing a focal plane shutter (FPS) to enable both nadir and significant side and forward oblique imaging angles. The impact of FPS for differential image motion compensation is evaluated with the exterior orientation calibration parameters, which include the existing shutter velocity and flight dynamics from sample mapping applications. System requirements for GPS/INS are included with the effect of vertical error and side oblique angle impact of the digital elevation map (DEM) required to create the orthophoto. Results from the differentiated "collinearity equations" which relate the image coordinates to elements of interior and exterior orientation are combined with the DEM impact to provide useful guidelines for side oblique applications. The application of real-time orthophotography is described with the implications for system requirements for side oblique orthophoto capability.

  6. Real-Time Detection and Tracking of Multiple People in Laser Scan Frames

    NASA Astrophysics Data System (ADS)

    Cui, J.; Song, X.; Zhao, H.; Zha, H.; Shibasaki, R.

    This chapter presents an approach to detect and track multiple people ro bustly in real time using laser scan frames. The detection and tracking of people in real time is a problem that arises in a variety of different contexts. Examples in clude intelligent surveillance for security purposes, scene analysis for service robot, and crowd behavior analysis for human behavior study. Over the last several years, an increasing number of laser-based people-tracking systems have been developed in both mobile robotics platforms and fixed platforms using one or multiple laser scanners. It has been proved that processing on laser scanner data makes the tracker much faster and more robust than a vision-only based one in complex situations. In this chapter, we present a novel robust tracker to detect and track multiple people in a crowded and open area in real time. First, raw data are obtained that measures two legs for each people at a height of 16 cm from horizontal ground with multiple registered laser scanners. A stable feature is extracted using accumulated distribu tion of successive laser frames. In this way, the noise that generates split and merged measurements is smoothed well, and the pattern of rhythmic swinging legs is uti lized to extract each leg. Second, a probabilistic tracking model is presented, and then a sequential inference process using a Bayesian rule is described. A sequential inference process is difficult to compute analytically, so two strategies are presented to simplify the computation. In the case of independent tracking, the Kalman fil ter is used with a more efficient measurement likelihood model based on a region coherency property. Finally, to deal with trajectory fragments we present a concise approach to fuse just a little visual information from synchronized video camera to laser data. Evaluation with real data shows that the proposed method is robust and effective. It achieves a significant improvement compared with existing laser

  7. Dynamics of supersonic microparticle impact on elastomers revealed by real–time multi–frame imaging

    PubMed Central

    Veysset, David; Hsieh, Alex J.; Kooi, Steven; Maznev, Alexei A.; Masser, Kevin A.; Nelson, Keith A.

    2016-01-01

    Understanding high–velocity microparticle impact is essential for many fields, from space exploration to medicine and biology. Investigations of microscale impact have hitherto been limited to post–mortem analysis of impacted specimens, which does not provide direct information on the impact dynamics. Here we report real–time multi–frame imaging studies of the impact of 7 μm diameter glass spheres traveling at 700–900 m/s on elastomer polymers. With a poly(urethane urea) (PUU) sample, we observe a hyperelastic impact phenomenon not seen on the macroscale: a microsphere undergoes a full conformal penetration into the specimen followed by a rebound which leaves the specimen unscathed. The results challenge the established interpretation of the behaviour of elastomers under high–velocity impact. PMID:27156501

  8. Dynamics of supersonic microparticle impact on elastomers revealed by real–time multi–frame imaging

    NASA Astrophysics Data System (ADS)

    Veysset, David; Hsieh, Alex J.; Kooi, Steven; Maznev, Alexei A.; Masser, Kevin A.; Nelson, Keith A.

    2016-05-01

    Understanding high–velocity microparticle impact is essential for many fields, from space exploration to medicine and biology. Investigations of microscale impact have hitherto been limited to post–mortem analysis of impacted specimens, which does not provide direct information on the impact dynamics. Here we report real–time multi–frame imaging studies of the impact of 7 μm diameter glass spheres traveling at 700–900 m/s on elastomer polymers. With a poly(urethane urea) (PUU) sample, we observe a hyperelastic impact phenomenon not seen on the macroscale: a microsphere undergoes a full conformal penetration into the specimen followed by a rebound which leaves the specimen unscathed. The results challenge the established interpretation of the behaviour of elastomers under high–velocity impact.

  9. Dynamics of supersonic microparticle impact on elastomers revealed by real-time multi-frame imaging.

    PubMed

    Veysset, David; Hsieh, Alex J; Kooi, Steven; Maznev, Alexei A; Masser, Kevin A; Nelson, Keith A

    2016-01-01

    Understanding high-velocity microparticle impact is essential for many fields, from space exploration to medicine and biology. Investigations of microscale impact have hitherto been limited to post-mortem analysis of impacted specimens, which does not provide direct information on the impact dynamics. Here we report real-time multi-frame imaging studies of the impact of 7 μm diameter glass spheres traveling at 700-900 m/s on elastomer polymers. With a poly(urethane urea) (PUU) sample, we observe a hyperelastic impact phenomenon not seen on the macroscale: a microsphere undergoes a full conformal penetration into the specimen followed by a rebound which leaves the specimen unscathed. The results challenge the established interpretation of the behaviour of elastomers under high-velocity impact. PMID:27156501

  10. Dynamics of supersonic microparticle impact on elastomers revealed by real-time multi-frame imaging.

    PubMed

    Veysset, David; Hsieh, Alex J; Kooi, Steven; Maznev, Alexei A; Masser, Kevin A; Nelson, Keith A

    2016-05-09

    Understanding high-velocity microparticle impact is essential for many fields, from space exploration to medicine and biology. Investigations of microscale impact have hitherto been limited to post-mortem analysis of impacted specimens, which does not provide direct information on the impact dynamics. Here we report real-time multi-frame imaging studies of the impact of 7 μm diameter glass spheres traveling at 700-900 m/s on elastomer polymers. With a poly(urethane urea) (PUU) sample, we observe a hyperelastic impact phenomenon not seen on the macroscale: a microsphere undergoes a full conformal penetration into the specimen followed by a rebound which leaves the specimen unscathed. The results challenge the established interpretation of the behaviour of elastomers under high-velocity impact.

  11. Achievement Motivation and Physical Fitness of 15-Year Old Girls

    ERIC Educational Resources Information Center

    Guszkowska, Monika; Rychta, Tadeusz

    2007-01-01

    Study aim: To determine the relations between the general and physical education-specific achievement motivation, and physical fitness of adolescent girls. Material and methods: A group of 52 girls aged 15 years were studied by applying two questionnaires: P-O scale of Widerszal-Bazyl for evaluating the general achievement motivation and Nishida's…

  12. Raising the Standard: A 15-Year Retrospective, 1987-2002.

    ERIC Educational Resources Information Center

    National Board for Professional Teaching Standards, Detroit, MI.

    This report describes the past 15 years of work by the National Board for Professional Teaching Standards (NBPTS) to raise the standards for teacher quality. The NBPTS identified five core propositions that describe the knowledge, skills, and dispositions characterizing accomplished teaching. It created professional standards for K-12 teachers,…

  13. Dynamics of high-speed micro-drop impact: numerical simulations and experiments at frame-to-frame times below 100 ns.

    PubMed

    Visser, Claas Willem; Frommhold, Philipp Erhard; Wildeman, Sander; Mettin, Robert; Lohse, Detlef; Sun, Chao

    2015-03-01

    Technologies including (3D-) (bio-)printing, diesel engines, laser-induced forward transfer, and spray cleaning require optimization and therefore understanding of micrometer-sized droplets impacting at velocities beyond 10 m s(-1). However, as yet, this regime has hardly been addressed. Here we present the first time-resolved experimental investigation of microdroplet impact at velocities up to V0 = 50 m s(-1), on hydrophilic and -phobic surfaces at frame rates exceeding 10(7) frames per second. A novel method to determine the 3D-droplet profile at sub-micron resolution at the same frame rates is presented, using the fringe pattern observed from a bottom view. A numerical model, which is validated by the side- and bottom-view measurements, is employed to study the viscous boundary layer inside the droplet and the development of the rim. The spreading dynamics, the maximal spreading diameter, the boundary layer thickness, the rim formation, and the air bubble entrainment are compared to theory and previous experiments. In general, the impact dynamics are equal to millimeter-sized droplet impact for equal Reynolds-, Weber- and Stokes numbers (Re, We, and St, respectively). Using our numerical model, effective scaling laws for the progression of the boundary layer thickness and the rim diameter are provided. The dimensionless boundary layer thickness develops in time (t) according to δBL ~ D0/√Re(t/τ)0.45, and the diameter of the rim develops as DRim ~ D0/√We(t/τ)0.68, with drop diameter D0 and inertial time scale τ = D0/V0. These scalings differ from previously assumed, but never validated, values. Finally, no splash is observed, at variance with many predictions but in agreement with models including the influence of the surrounding gas. This confirms that the ambient gas properties are key ingredients for splash threshold predictions.

  14. Dynamics of high-speed micro-drop impact: numerical simulations and experiments at frame-to-frame times below 100 ns.

    PubMed

    Visser, Claas Willem; Frommhold, Philipp Erhard; Wildeman, Sander; Mettin, Robert; Lohse, Detlef; Sun, Chao

    2015-03-01

    Technologies including (3D-) (bio-)printing, diesel engines, laser-induced forward transfer, and spray cleaning require optimization and therefore understanding of micrometer-sized droplets impacting at velocities beyond 10 m s(-1). However, as yet, this regime has hardly been addressed. Here we present the first time-resolved experimental investigation of microdroplet impact at velocities up to V0 = 50 m s(-1), on hydrophilic and -phobic surfaces at frame rates exceeding 10(7) frames per second. A novel method to determine the 3D-droplet profile at sub-micron resolution at the same frame rates is presented, using the fringe pattern observed from a bottom view. A numerical model, which is validated by the side- and bottom-view measurements, is employed to study the viscous boundary layer inside the droplet and the development of the rim. The spreading dynamics, the maximal spreading diameter, the boundary layer thickness, the rim formation, and the air bubble entrainment are compared to theory and previous experiments. In general, the impact dynamics are equal to millimeter-sized droplet impact for equal Reynolds-, Weber- and Stokes numbers (Re, We, and St, respectively). Using our numerical model, effective scaling laws for the progression of the boundary layer thickness and the rim diameter are provided. The dimensionless boundary layer thickness develops in time (t) according to δBL ~ D0/√Re(t/τ)0.45, and the diameter of the rim develops as DRim ~ D0/√We(t/τ)0.68, with drop diameter D0 and inertial time scale τ = D0/V0. These scalings differ from previously assumed, but never validated, values. Finally, no splash is observed, at variance with many predictions but in agreement with models including the influence of the surrounding gas. This confirms that the ambient gas properties are key ingredients for splash threshold predictions. PMID:25607820

  15. Full-Field Spectroscopy at Megahertz-frame-rates: Application of Coherent Time-Stretch Transform

    NASA Astrophysics Data System (ADS)

    DeVore, Peter Thomas Setsuda

    Outliers or rogue events are found extensively in our world and have incredible effects. Also called rare events, they arise in the distribution of wealth (e.g., Pareto index), finance, network traffic, ocean waves, and e-commerce (selling less of more). Interest in rare optical events exploded after the sighting of optical rogue waves in laboratory experiments at UCLA. Detecting such tail events in fast streams of information necessitates real-time measurements. The Coherent Time-Stretch Transform chirps a pulsed source of radiation so that its temporal envelope matches its spectral profile (analogous to the far field regime of spatial diffraction), and the mapped spectral electric field is slow enough to be captured by a real-time digitizer. Combining this technique with spectral encoding, the time stretch technique has enabled a new class of ultra-high performance spectrometers and cameras (30+ MHz), and analog-to-digital converters that have led to the discovery of optical rogue waves and detection of cancer cells in blood with one in a million sensitivity. Conventionally, the Coherent Time-Stretch Transform maps the spectrum into the temporal electric field, but the time-dilation process along with inherent fiber losses results in reduction of peak power and loss of sensitivity, a problem exacerbated by extremely narrow molecular linewidths. The loss issue notwithstanding, in many cases the requisite dispersive optical device is not available. By extending the Coherent Time-Stretch Transform to the temporal near field, I have demonstrated, for the first time, phase-sensitive absorption spectroscopy of a gaseous sample at millions of frames per second. As the Coherent Time-Stretch Transform may capture both near and far field optical waves, it is a complete spectro-temporal optical characterization tool. This is manifested as an amplitude-dependent chirp, which implies the ability to measure the complex refractive index dispersion at megahertz frame rates. This

  16. Time-resolved measurement technique for pulsed electron beam envelope basing on framing and streaking principle

    NASA Astrophysics Data System (ADS)

    Jiang, Xiao-Guo; Wang, Yuan; Yang, Zhi-Yong; Zhang, Huang; Wang, Yi

    2016-01-01

    The time-resolved electron beam envelope parameters, including cross sectional distribution and beam centroid position, are very important for the study of beam transmission characteristics in a magnetic field and for verifying the rationality of the magnetic field parameters employed. One kind of high time-resolved beam envelope measurement system has recently been developed, constituted of a high-speed framing camera and a streak camera. It can obtain three panoramic images of the beam and time continuous information along the given beam profile simultaneously. Recently obtained data has proved that several fast vibrations of the beam envelope along the diameter direction occur during the front and the tail parts of the electron beam. The vibration period is several nanoseconds. The effect of magnetic field on the electron beam is also observed and verified. Beam debugging experiments have proved that the existing beam transmission design is reasonable and viable. This beam envelope measurement system will establish a good foundation for beam physics research. Supported by National Natural Science Foundation of China (10675104, 11375162)

  17. Lytic Cycle of Toxoplasma gondii: 15 Years Later.

    PubMed

    Blader, Ira J; Coleman, Bradley I; Chen, Chun-Ti; Gubbels, Marc-Jan

    2015-01-01

    Toxoplasmosis is the clinical and pathological consequence of acute infection with the obligate intracellular apicomplexan parasite Toxoplasma gondii. Symptoms result from tissue destruction that accompanies lytic parasite growth. This review updates current understanding of the host cell invasion, parasite replication, and eventual egress that constitute the lytic cycle, as well as the ways T. gondii manipulates host cells to ensure its survival. Since the publication of a previous iteration of this review 15 years ago, important advances have been made in our molecular understanding of parasite growth and mechanisms of host cell egress, and knowledge of the parasite's manipulation of the host has rapidly progressed. Here we cover molecular advances and current conceptual frameworks that include each of these topics, with an eye to what may be known 15 years from now.

  18. AFFECT AND THE FRAMING EFFECT WITHIN INDIVIDUALS OVER TIME: RISK TAKING IN A DYNAMIC INVESTMENT SIMULATION

    PubMed Central

    SEO, MYEONG-GU; GOLDFARB, BRENT; BARRETT, LISA FELDMAN

    2011-01-01

    We examined the role of affect (pleasant or unpleasant feelings) and decision frames (gains or losses) in risk taking in a 20-day stock investment simulation in which 101 participants rated their current feelings while making investment decisions. As predicted, affect attenuated the relationships between decision frames and risk taking. After experiencing losses, individuals made more risky choices, in keeping with the framing effect. However, this tendency decreased and/or disappeared when loss was simultaneously experienced with either pleasant or unpleasant feelings. Similarly, individuals’ tendency to avoid risk after experiencing gains disappeared or even reversed when they simultaneously experienced pleasant feelings. PMID:26412860

  19. Time-Resolved Molecular Frame Dynamics of Fixed-in-Space CS2 Molecules

    SciTech Connect

    Bisgaard, Christer; Clarkin, Owen; Wu, Guorong; Lee, Anthony; Gessner, Oliver; Hayden, Carl; Stolow, Albert

    2009-04-02

    Random orientation of molecules within a sample leads to blurred observationsof chemical reactions studied from the laboratory perspective. Methodsdeveloped for the dynamic imaging of molecular structures and processesstruggle with this, as measurements are optimally made in the molecular frame.Here we uselaser alignment to transiently fix CS2 molecules in space longenough to elucidate, in the molecular reference frame, details of ultrafast electronic vibrationaldynamics during a photochemical reaction. These three-dimensional photoelectron imaging results, combined with ongoing efforts in molecular alignment and orientation, presage a wide range of insights obtainable fromtime-resolved studies in the molecular frame.

  20. Frame-Transfer Gating Raman Spectroscopy for Time-Resolved Multiscalar Combustion Diagnostics

    NASA Technical Reports Server (NTRS)

    Nguyen, Quang-Viet; Fischer, David G.; Kojima, Jun

    2011-01-01

    Accurate experimental measurement of spatially and temporally resolved variations in chemical composition (species concentrations) and temperature in turbulent flames is vital for characterizing the complex phenomena occurring in most practical combustion systems. These diagnostic measurements are called multiscalar because they are capable of acquiring multiple scalar quantities simultaneously. Multiscalar diagnostics also play a critical role in the area of computational code validation. In order to improve the design of combustion devices, computational codes for modeling turbulent combustion are often used to speed up and optimize the development process. The experimental validation of these codes is a critical step in accepting their predictions for engine performance in the absence of cost-prohibitive testing. One of the most critical aspects of setting up a time-resolved stimulated Raman scattering (SRS) diagnostic system is the temporal optical gating scheme. A short optical gate is necessary in order for weak SRS signals to be detected with a good signal- to-noise ratio (SNR) in the presence of strong background optical emissions. This time-synchronized optical gating is a classical problem even to other spectroscopic techniques such as laser-induced fluorescence (LIF) or laser-induced breakdown spectroscopy (LIBS). Traditionally, experimenters have had basically two options for gating: (1) an electronic means of gating using an image intensifier before the charge-coupled-device (CCD), or (2) a mechanical optical shutter (a rotary chopper/mechanical shutter combination). A new diagnostic technology has been developed at the NASA Glenn Research Center that utilizes a frame-transfer CCD sensor, in conjunction with a pulsed laser and multiplex optical fiber collection, to realize time-resolved Raman spectroscopy of turbulent flames that is free from optical background noise (interference). The technology permits not only shorter temporal optical gating (down

  1. Leprosy among children under 15 years of age: literature review*

    PubMed Central

    de Oliveira, Marcela Bahia Barretto; Diniz, Lucia Martins

    2016-01-01

    Leprosy is a chronic infectious disease caused by Mycobacterium leprae, representing a public health issue in some countries. Though more prevalent in adults, the detection of new cases in children under 15 years of age reveals an active circulation of bacillus, continued transmission and lack of disease control by the health system, as well as aiding in the monitoring of the endemic. Among patients under 15 years of age, the most affected age group is children between 10 and 14 years of age, although cases of patients of younger than 1 year of age have also been reported. Household contacts are the primary source of infection, given that caretakers, such as babysitters and others, must be considered in this scenario. Paucibacillary forms of the disease prevailed, especially borderline-tuberculoid leprosy, with a single lesion in exposed areas of the body representing the main clinical manifestation. Reactional states: Lepra reactions are rare, although some authors have reported high frequencies of this phenomenon, the most frequent of which is Type 1 Lepra Reaction. Peripheral nerve involvement has been described at alarming rates in some studies, which increases the chance of deformities, a serious problem, especially if one considers the age of these patients. The protective effect of BCG vaccination was found in some studies, but no consensus has been reached among different authors. Children must receive the same multidrug therapy regimen and the doses should, ideally, be calculated based on the child´s weight. Adverse reactions to this therapy are rare within this age group. This article aims to review epidemiological, clinical, and therapeutic aspects of leprosy in patients under 15 years of age. PMID:27192519

  2. Leprosy among children under 15 years of age: literature review.

    PubMed

    Oliveira, Marcela Bahia Barretto de; Diniz, Lucia Martins

    2016-04-01

    Leprosy is a chronic infectious disease caused by Mycobacterium leprae, representing a public health issue in some countries. Though more prevalent in adults, the detection of new cases in children under 15 years of age reveals an active circulation of bacillus, continued transmission and lack of disease control by the health system, as well as aiding in the monitoring of the endemic. Among patients under 15 years of age, the most affected age group is children between 10 and 14 years of age, although cases of patients of younger than 1 year of age have also been reported. Household contacts are the primary source of infection, given that caretakers, such as babysitters and others, must be considered in this scenario. Paucibacillary forms of the disease prevailed, especially borderline-tuberculoid leprosy, with a single lesion in exposed areas of the body representing the main clinical manifestation. Reactional states: Lepra reactions are rare, although some authors have reported high frequencies of this phenomenon, the most frequent of which is Type 1 Lepra Reaction. Peripheral nerve involvement has been described at alarming rates in some studies, which increases the chance of deformities, a serious problem, especially if one considers the age of these patients. The protective effect of BCG vaccination was found in some studies, but no consensus has been reached among different authors. Children must receive the same multidrug therapy regimen and the doses should, ideally, be calculated based on the child´s weight. Adverse reactions to this therapy are rare within this age group. This article aims to review epidemiological, clinical, and therapeutic aspects of leprosy in patients under 15 years of age. PMID:27192519

  3. Bronchial Leech Infestation in a 15-Year-Old Female

    PubMed Central

    Moslehi, Mohammad Ashkan; Imanieh, Mohammad Hadi

    2016-01-01

    Foreign body aspiration (FBA) is a common incidence in young children. Leeches are rarely reported as FBA at any age. This study describes a 15-year-old female who presented with hemoptysis, hematemesis, coughs, melena, and anemia seven months prior to admission. Chest X-ray showed a round hyperdensity in the right lower lobe. A chest computed tomography (CT) demonstrated an area of consolidation and surrounding ground glass opacities in the right lower lobe. Hematological investigations revealed anemia. Finally, bronchoscopy was performed and a 5 cm leech was found within the right B7-8 bronchus and removed by forceps and a Dormia basket. PMID:27752380

  4. [Socio-demographic impact of 15 years of family planning].

    PubMed

    Rosales Aujang, Enrique; Felguérez Flores, Jesús Alberto

    2005-08-01

    Familiar planning is an important branch of the preventive medicine that can have a great impact on the health of the humanity. The present study is an evaluation by a cross section of the effects obtained by the program of familiar planning during a period of 15 years in the Aguascalientes Delegation of the Mexican Institute of the Social Security, establishing therefore a diagnosis and identifying elements that can contribute in the suitable planning of strategies to improve the quality of the attention and to respond to social and health necessities of the population.

  5. Optical cell tracking analysis using a straight-forward approach to minimize processing time for high frame rate data.

    PubMed

    Seeto, Wen Jun; Lipke, Elizabeth Ann

    2016-03-01

    Tracking of rolling cells via in vitro experiment is now commonly performed using customized computer programs. In most cases, two critical challenges continue to limit analysis of cell rolling data: long computation times due to the complexity of tracking algorithms and difficulty in accurately correlating a given cell with itself from one frame to the next, which is typically due to errors caused by cells that either come close in proximity to each other or come in contact with each other. In this paper, we have developed a sophisticated, yet simple and highly effective, rolling cell tracking system to address these two critical problems. This optical cell tracking analysis (OCTA) system first employs ImageJ for cell identification in each frame of a cell rolling video. A custom MATLAB code was written to use the geometric and positional information of all cells as the primary parameters for matching each individual cell with itself between consecutive frames and to avoid errors when tracking cells that come within close proximity to one another. Once the cells are matched, rolling velocity can be obtained for further analysis. The use of ImageJ for cell identification eliminates the need for high level MATLAB image processing knowledge. As a result, only fundamental MATLAB syntax is necessary for cell matching. OCTA has been implemented in the tracking of endothelial colony forming cell (ECFC) rolling under shear. The processing time needed to obtain tracked cell data from a 2 min ECFC rolling video recorded at 70 frames per second with a total of over 8000 frames is less than 6 min using a computer with an Intel® Core™ i7 CPU 2.80 GHz (8 CPUs). This cell tracking system benefits cell rolling analysis by substantially reducing the time required for post-acquisition data processing of high frame rate video recordings and preventing tracking errors when individual cells come in close proximity to one another. PMID:27036782

  6. Optical cell tracking analysis using a straight-forward approach to minimize processing time for high frame rate data

    NASA Astrophysics Data System (ADS)

    Seeto, Wen Jun; Lipke, Elizabeth Ann

    2016-03-01

    Tracking of rolling cells via in vitro experiment is now commonly performed using customized computer programs. In most cases, two critical challenges continue to limit analysis of cell rolling data: long computation times due to the complexity of tracking algorithms and difficulty in accurately correlating a given cell with itself from one frame to the next, which is typically due to errors caused by cells that either come close in proximity to each other or come in contact with each other. In this paper, we have developed a sophisticated, yet simple and highly effective, rolling cell tracking system to address these two critical problems. This optical cell tracking analysis (OCTA) system first employs ImageJ for cell identification in each frame of a cell rolling video. A custom MATLAB code was written to use the geometric and positional information of all cells as the primary parameters for matching each individual cell with itself between consecutive frames and to avoid errors when tracking cells that come within close proximity to one another. Once the cells are matched, rolling velocity can be obtained for further analysis. The use of ImageJ for cell identification eliminates the need for high level MATLAB image processing knowledge. As a result, only fundamental MATLAB syntax is necessary for cell matching. OCTA has been implemented in the tracking of endothelial colony forming cell (ECFC) rolling under shear. The processing time needed to obtain tracked cell data from a 2 min ECFC rolling video recorded at 70 frames per second with a total of over 8000 frames is less than 6 min using a computer with an Intel® Core™ i7 CPU 2.80 GHz (8 CPUs). This cell tracking system benefits cell rolling analysis by substantially reducing the time required for post-acquisition data processing of high frame rate video recordings and preventing tracking errors when individual cells come in close proximity to one another.

  7. Quantum mechanics in non-inertial reference frames: Time-dependent rotations and loop prolongations

    NASA Astrophysics Data System (ADS)

    Klink, W. H.; Wickramasekara, S.

    2013-09-01

    This is the fourth in a series of papers on developing a formulation of quantum mechanics in non-inertial reference frames. This formulation is grounded in a class of unitary cocycle representations of what we have called the Galilean line group, the generalization of the Galilei group to include transformations amongst non-inertial reference frames. These representations show that in quantum mechanics, just as the case in classical mechanics, the transformations to accelerating reference frames give rise to fictitious forces. In previous work, we have shown that there exist representations of the Galilean line group that uphold the non-relativistic equivalence principle as well as representations that violate the equivalence principle. In these previous studies, the focus was on linear accelerations. In this paper, we undertake an extension of the formulation to include rotational accelerations. We show that the incorporation of rotational accelerations requires a class of loop prolongations of the Galilean line group and their unitary cocycle representations. We recover the centrifugal and Coriolis force effects from these loop representations. Loops are more general than groups in that their multiplication law need not be associative. Hence, our broad theoretical claim is that a Galilean quantum theory that holds in arbitrary non-inertial reference frames requires going beyond groups and group representations, the well-established framework for implementing symmetry transformations in quantum mechanics.

  8. Quantum mechanics in non-inertial reference frames: Time-dependent rotations and loop prolongations

    SciTech Connect

    Klink, W.H.; Wickramasekara, S.

    2013-09-15

    This is the fourth in a series of papers on developing a formulation of quantum mechanics in non-inertial reference frames. This formulation is grounded in a class of unitary cocycle representations of what we have called the Galilean line group, the generalization of the Galilei group to include transformations amongst non-inertial reference frames. These representations show that in quantum mechanics, just as the case in classical mechanics, the transformations to accelerating reference frames give rise to fictitious forces. In previous work, we have shown that there exist representations of the Galilean line group that uphold the non-relativistic equivalence principle as well as representations that violate the equivalence principle. In these previous studies, the focus was on linear accelerations. In this paper, we undertake an extension of the formulation to include rotational accelerations. We show that the incorporation of rotational accelerations requires a class of loop prolongations of the Galilean line group and their unitary cocycle representations. We recover the centrifugal and Coriolis force effects from these loop representations. Loops are more general than groups in that their multiplication law need not be associative. Hence, our broad theoretical claim is that a Galilean quantum theory that holds in arbitrary non-inertial reference frames requires going beyond groups and group representations, the well-established framework for implementing symmetry transformations in quantum mechanics. -- Highlights: •A formulation of Galilean quantum mechanics in non-inertial reference frames is presented. •The Galilei group is generalized to infinite dimensional Galilean line group. •Loop prolongations of Galilean line group contain central extensions of Galilei group. •Unitary representations of the loops are constructed. •These representations lead to terms in the Hamiltonian corresponding to fictitious forces, including centrifugal and Coriolis

  9. Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy.

    PubMed

    Liu, Fang; Yan, Wen Liang; Liu, Haibo; Zhang, Min; Sang, Hong

    2015-01-01

    We report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma. Histopathologic examination revealed poorly differentiated adenocarcinoma cells. They were stained positive for villin, CDX-2, CKpan (AE1/ AE3), CEA, CK8/18, CK19, CK7, EMA, Ki-67 (50%), and negative for S-100, CK20, CD34, GCDFP-15 and TTF-1. The patient underwent local excision, after the presence of other metastases was excluded. Nevertheless, local recurrence developed at the surgical bed one year later and PET/CT revealed metastases to lymph nodes, bone and skin. He died 2 years after the appearance of cutaneous metastases. We have reviewed the literature and described the immunohistochemical characteristics of cutaneous metastases from gastric adenocarcinoma. PMID:26312672

  10. Towards understanding software: 15 years in the SEL

    NASA Technical Reports Server (NTRS)

    Mcgarry, Frank; Pajerski, Rose

    1990-01-01

    For 15 years, the Software Engineering Laboratory (SEL) at GSFC has been carrying out studies and experiments for the purpose of understanding, assessing, and improving software, and software processes within a production software environment. The SEL comprises three major organizations: (1) the GSFC Flight Dynamics Division; (2) the University of Maryland Computer Science Department; and (3) the Computer Sciences Corporation Flight Dynamics Technology Group. These organizations have jointly carried out several hundred software studies, producing hundreds of reports, papers, and documents: all describing some aspect of the software engineering technology that has undergone analysis in the flight dynamics environment. The studies range from small controlled experiments (such as analyzing the effectiveness of code reading versus functional testing) to large, multiple-project studies (such as assessing the impacts of Ada on a production environment). The key findings that NASA feels have laid the foundation for ongoing and future software development and research activities are summarized.

  11. [Application of variable magnetic fields in medicine--15 years experience].

    PubMed

    Sieroń, Aleksander; Cieślar, Grzegorz

    2003-01-01

    The results of 15-year own experimental and clinical research on application of variable magnetic fields in medicine were presented. In experimental studies analgesic effect (related to endogenous opioid system and nitrogen oxide activity) and regenerative effect of variable magnetic fields with therapeutical parameters was observed. The influence of this fields on enzymatic and hormonal activity, free oxygen radicals, carbohydrates, protein and lipid metabolism, dielectric and rheological properties of blood as well as behavioural reactions and activity of central dopamine receptor in experimental animals was proved. In clinical studies high therapeutic efficacy of magnetotherapy and magnetostimulation in the treatment of osteoarthrosis, abnormal ossification, osteoporosis, nasosinusitis, multiple sclerosis, Parkinson's disease, spastic paresis, diabetic polyneuropathy and retinopathy, vegetative neurosis, peptic ulcers, colon irritable and trophic ulcers was confirmed. PMID:15049208

  12. The Iberoamerican Cerebrovascular Diseases Society: 15 years moving forward.

    PubMed

    Del Brutto, Oscar H; Diez-Tejedor, Exuperio; Sacks, Claudio; Ameriso, Sebastián F; Náder, Juan; Alonso de Leciñana, María; Massaro, Ayrton

    2013-06-01

    The Iberoamerican Cerebrovascular Diseases Society was founded 15 years ago. Being aware of the increased burden of stroke in Latin America, its members have been working to enhance the knowledge on stroke among physicians in the region, to increase public awareness on stroke warning signs, and to motivate public health authorities to implement programs that speed the access of stroke patients to specialized units. Besides organizing annual meetings that have convened an increasing number of attendees, the Society has been actively involved in the elaboration of guidelines for stroke classification and therapy that will be practical for use at a regional level, as well as in the consolidation of links with other stroke societies to increase the diffusion of local stroke issues to the medical community at large. The Society is also involved in the Safe Implementation of Treatment in Stroke trial as well as in other studies that will increase the knowledge on stroke management and prognosis in the region.

  13. [Renal cell carcinoma metastasis to the thyroid gland 15 years after nephrectomy].

    PubMed

    Mathiesen, Jes Sloth; Fleischer, Jens Geelmuyden; Godballe, Christian

    2015-01-26

    Renal cell carcinoma (RCC) metastasis to the thyroid gland is rare and can mimic primary thyroid carcinoma leading to diagnostic difficulties. We present a case of a 55-year-old female with RCC metastasis to the thyroid gland 15 years after nephrectomy. Diagnosis was made after total thyroidectomy. This case emphasizes the importance of considering metastasis in patients with increasing growth of the thyroid gland over a short period of time known with earlier RCC, even decades after nephrectomy. PMID:25612964

  14. MOSFET solid state switching circuit improves the 0 to 99% rise time for framing camera deflection electronics

    SciTech Connect

    Rivera, A.T.; Thomas, S.

    1996-09-01

    We have improved the 0 to 99% rise time voltage on our 2 frame deflection plates from 160 to 65 nS with the addition of a peaking circuit that works in conjunction with our primary 2 frame deflection circuitry. Our peaking technique has applications to other HV pulsers including those which must drive 51 ohm loads. Generally, rise time voltages are measured between 10 and 90%. To minimize the camera image blur resulting from the dynamic influence of deflection plate potentials acting on photocathode electrons, it was necessary to design a circuit that would rise from 0 to the 99% voltage level in under 100nS. Once this voltage was reached, it was necessary to stay within 1% of the attained voltage level for a duration of 1 uS. This was accomplished with the use of MOSFET solid state switching.

  15. Asymptomatic abdominal wall endometrioma 15 years after cesarean section.

    PubMed

    Tica, V I; Tomescu, C L; Tomescu, Aneta; Micu, Luminiţa; Zaher, M; Bafani, S; Beghim, M; Serbănescu, L; Tica, Irina

    2006-01-01

    Abdominal wall endometriosis is rare and its diagnosis is difficult. However, the consequences may be serious, like recurrences or even malignant transformation. We report a rarer case of asymptomatic abdominal wall endometrioma, accidentally found during a surgical procedure for a second cesarean section, in a 39-years old patient, without any relevant history of endometriosis. The tumor was subcutaneous, 3/3 cm in size, located in the left angle of the incision from the 15 years previously performed cesarean section and freely mobile in relation with the skin and the fascia. It was excised, with clear margins (to prevent recurrences), during the procedure. The patient was discharged after five days. The postoperative period and the follow-up at one and three months were uneventful. The pathological examination clarified the diagnosis by revealing an endometrioma with decidual reaction. Such a condition may be, therefore, evoked before an abdominal wall tumor, even without specific symptoms, even in a 39-years old woman and longtime after the possible causal surgery. Pathological examination remains the ultimate diagnostic tool. Relevant prophylactic attitude at the end of the cesarean section may be considered.

  16. Dynamic Characteristic Analysis of Spinal Motor Control Between 11- and 15-Year-Old Children.

    PubMed

    Chow, Daniel H; Lau, Newman M

    2016-07-01

    Spinal motor control can provide substantial insight for the causes of spinal musculoskeletal disorders. Its dynamic characteristics however, have not been fully investigated. The objective of this study is to explore the dynamic characteristics of spinal motor control via the fractional Brownian motion mathematical technique. Spinal curvatures and repositioning errors of different spinal regions in 64 children age 11- or 15-years old during upright stance were measured and compared for the effects of age and gender. With the application of the fractional Brownian motion analytical technique to the changes of spinal curvatures, distinct persistent movement behaviors could be determined, which could be interpreted physiologically as open-loop behaviors. Moreover, it was found that the spinal motor control of 15-year-old children was better than that of 11-year-old children with smaller repositioning error and less curvature variability as well as shorter response time and smaller curvature deformation.

  17. 15 years experience with helium ion radiotherapy for uvealmelanoma

    SciTech Connect

    Castro, Joseph R.; D.H. Char, P.L. Petti; Daftarii, K.; Quivey,J.M.; Singh, R.P.; Blakeley, E.A.; Phillips, T.L.

    1997-06-01

    Purpose: To review the long-term experience of helium iontherapy as a therapeutic alternative to enucleation for uveal melanoma,particularly with respect to survival, local control, and morbidity.Methods and Materials: 347 patients with uveal melanoma were treated withheluim ion RT from 1978-1992. A nonrandomized dose-searching study wasundertaken, with doses progressively reduced from 80 GyE in fivefractionsto 48 GyE in four fractions, given in 3-15 days, mean of 7days. Results: Local control was achieved in 96 percent of patients, withno difference in the rate of local control being seen at 80, 70, 60, or50 GyE in five fractions. At the lowest dose level of 48 GyE in fourfractions, the local control rate fell to 87 percent. Fifteen of 347patients (4 percent) had local regrowth in the eye requiring enucleation(12 patients), laser (1 patient) or reirradiation (2 patients). The timeof appearance of local regrowth ranged from 4 months to 5 yearsposttreatment, with 85 percent occurring within 3 years. Of the 347patients, 208 are alive as of May 1, 1997. The median follow up of allpatients is 8.5 years, range 1-17 years. Kaplan-Maier (K-M) survival is80 percent at 5 years, 76 percent at 10 years, and 72 percent at 15 yearsposttreatment. Patients with tumors not involving the ciliary body have a15-year K-M survival of 80 percent. The results for patients whose tumorsinvolved the ciliary body are poor, with a 15-year K-M survival of 43percent. Seventy-five percent of patients with tumors at least 3.0 mmfrom the fovea and optic nerve, and initial ultrasound height less than6.0 mm, retained vision of 20/200 or better posttreatment. Patients withtumors larger than 6 mm in thickness, or with tumors lying close to theoptic nerve or fovea, have a reduced chance of retaining useful vision.The enucleation rate is 19 percent, 3 percent for local failure and 16percent because of complications of the helium RT, particularlyneovascular glaucoma, which occurred in 35 percent of

  18. Early-onset schizophrenia: a 15-year follow-up.

    PubMed

    Röpcke, Bernd; Eggers, Christian

    2005-09-01

    The study describes the psychopathological and social outcome of patients treated for schizophrenia in adolescence (mean age at onset 16.0 years/SD 1.52) after a mean follow-up period of 15.4 years (10.2-21.2 years). Out of 55 patients consecutively admitted to hospital, 47 (85 %) could be traced and 39 (71 %) could be re-examined. At follow-up, 33/39 patients (85 %) had had at least one readmission. Full remission of global psychopathological symptoms [Clinical Global Impression (CGI) 15 years. In 26/37 cases (70 %), diagnosis at onset and overall diagnoses were the same. Our finding of an incidence of 61% insidious onset is similar to that in adult onset schizophrenia (AOS), but different to very early onset schizophrenia (VEOS), which shows a higher rate of insidious onset, cognitive impairment and poor outcome. Therefore, it seems that VEOS is a special group compared with early onset schizophrenia (EOS) and AOS. PMID:16220219

  19. Patterns of Weight Control Behavior among 15 year old Girls

    PubMed Central

    Balantekin, Katherine N.; Birch, Leann L.; Savage, Jennifer S.

    2015-01-01

    Objective The objectives were to identify and predict patterns of weight control behavior in 15 year old (yo) girls and to examine weight control group differences in energy intake. Method Subjects included 166 girls assessed every 2 years (ys) from age 5 to 15. Latent class analysis was used to identify patterns of weight control behaviors. Antecedent variables (e.g. inhibitory control at 7ys), and concurrent variables (e.g. BMI and dietary intake at 15ys) were included as predictors. Assessments were a combination of survey, interview, and laboratory measures. Results LCA identified four classes of weight control behaviors, Non-dieters (26%), and three dieting groups: Lifestyle (16%), Dieters (43%), and Extreme Dieters (17%). Levels of restraint, weight concerns, and dieting frequency increased across groups, from Non-dieters to Extreme Dieters. BMI at 5ys and inhibitory control at 7ys predicted weight control group at 15ys; e.g. with every one-point decrease in inhibitory control, girls were twice as likely to be Extreme Dieters than Non-dieters. Girls in the Extreme Dieters group were mostly classified as under-reporters, and had the lowest self-reported intake, but ate significantly more in the laboratory. Discussion Among 15yo girls, “dieting” includes a range of both healthy and unhealthy behaviors. Risk factors for membership in a weight control groups are present as early as 5ys. Patterns of intake in the laboratory support the view that lower reported energy intake by Extreme Dieters is likely due under-reporting as an intent to decrease intake, not actual decreased intake. PMID:26284953

  20. Automating Frame Analysis

    SciTech Connect

    Sanfilippo, Antonio P.; Franklin, Lyndsey; Tratz, Stephen C.; Danielson, Gary R.; Mileson, Nicholas D.; Riensche, Roderick M.; McGrath, Liam

    2008-04-01

    Frame Analysis has come to play an increasingly stronger role in the study of social movements in Sociology and Political Science. While significant steps have been made in providing a theory of frames and framing, a systematic characterization of the frame concept is still largely lacking and there are no rec-ognized criteria and methods that can be used to identify and marshal frame evi-dence reliably and in a time and cost effective manner. Consequently, current Frame Analysis work is still too reliant on manual annotation and subjective inter-pretation. The goal of this paper is to present an approach to the representation, acquisition and analysis of frame evidence which leverages Content Analysis, In-formation Extraction and Semantic Search methods to provide a systematic treat-ment of a Frame Analysis and automate frame annotation.

  1. Demonstration of 11-ps exposure time of a framing camera using pulse-dilation technology and a magnetic lens

    NASA Astrophysics Data System (ADS)

    Bai, Yanli; Long, Jinghua; Liu, Jinyuan; Cai, Houzhi; Niu, Lihong; Zhang, Dongfang; Ma, Xue; Liu, Dan; Yang, Qinlao; Niu, Hanben

    2015-12-01

    A framing camera with high temporal and spatial resolution is demonstrated using pulse-dilation technology and a magnetic lens. The magnetic field of the magnetic lens is simulated using LORENTZ-3EM software, and the magnetic field distribution on-axis is similar to a Gaussian function. The temporal and spatial resolutions of the instrument are measured using light at the wavelength of 266 nm from a frequency tripled femtosecond laser. The measured exposure time of this camera is ˜11 ps, and the spatial resolution is better than 100 μm.

  2. Framing Health Messages for Adolescents: Should We Use Objective Time Periods, Temporal Benchmarks, or Both?

    ERIC Educational Resources Information Center

    McKay, Michael T.; Cole, Jon C.; Sumnall, Harry R.; Goudie, Andrew J.

    2012-01-01

    Time perspective is a cognitive-motivational construct, which has been shown to be related to decision-making, motivation and adjustment. The majority of research into time perspective has been conducted in college students and/or general population samples. Focus groups were held as part of a larger investigation into the relationship between…

  3. Multihit two-dimensional charged-particle imaging system with real-time image processing at 1000 frames/s

    NASA Astrophysics Data System (ADS)

    Horio, Takuya; Suzuki, Toshinori

    2009-01-01

    A high-speed imaging system developed for two-dimensional counting of charged particles is presented. Microchannel plates coupled with a phosphor screen of a short emission lifetime (<1 μs) are used to visualize the two-dimensional positions of charged-particle impacts, and the image on the phosphor screen is captured with a 1 kHz complementary metal oxide semiconductor (CMOS) image sensor (512×512 pixels). A multistage image intensifier consisting of the first and second generation devices was used to compensate for the low sensitivity of CMOS. The centers of gravity (COG) of individual light spots in each image frame are calculated in real time by a field programmable gate array circuit. The performance of this system is tested by time-resolved photoelectron imaging (TR-PEI) of NO using (1+1') resonance enhanced multiphoton ionization via the A Σ2+ state with a femtosecond laser operated at 1 kHz. The new system enabled COG detection for more than ten particles in each frame at 1 kHz and achieved an extremely high degree of accuracy in the measurement of photoelectron angular distributions in TR-PEI.

  4. "simplest Molecule" Clarifies Modern Physics I. Cw Laser Space-Time Frame Dynamics

    NASA Astrophysics Data System (ADS)

    Reimer, T. C.; Harter, W. G.

    2014-06-01

    Molecular spectroscopy makes very precise applications of quantum theory including GPS, BEC, and laser clocks. Now it can return the favor by shedding some light on modern physics mysteries by further unifying quantum theory and relativity. * We first ask, "What is the simplest molecule?" Hydrogen H2 is the simplest, stable molecule. Positronium is an electron-positron (e+e-)-pair. An even simpler "molecule" or "radical" is a photon-pair (γ, γ) that under certain conditions can create an (e+e-)-pair. * To help unravel relativistic and quantum mysteries consider CW laser beam pairs or TE-waveguides. Remarkably, their wave interference immediately gives Minkowski space-time coordinates and clearly relates eight kinds of space-time wave dilations or contractions to shifts in Doppler frequency or wavenumber. * Modern physics students may find this approach significantly simplifies and clarifies relativistic physics in space-time (x,ct) and inverse time-space (ω,ck). It resolves some mysteries surrounding super-constant c=299,792,458m/s by proving "Evenson's Axiom" named in honor of NIST metrologist Ken Evenson (1932-2002) whose spectroscopy established c to start a precision-renaissance in spectroscopy and GPS metrology. * The following Talk II applies this approach to relativistic quantum mechanics.

  5. ``Simplest Molecule'' Clarifies Modern Physics I. CW Laser Space-Time Frame Dynamics

    NASA Astrophysics Data System (ADS)

    Reimer, Tyle; Harter, William

    2015-05-01

    Molecular spectroscopy makes very precise applications of quantum theory including GPS, BEC, and laser clocks. Now it can return the favor by shedding some light on modern physics mysteries by further unifying quantum theory and relativity. We first ask, ``What is the simplest molecule?'' Hydrogen H2 is the simplest stable molecule. Positronium is an electron-positron (e+e-) -pair. An even simpler ``molecule'' or ``radical'' is a photon-pair (γ, γ) that under certain conditions can create an (e+e-) -pair. To help unravel relativistic and quantum mysteries consider CW laser beam pairs or TE-waveguides. Remarkably, their wave interference immediately gives Minkowski space-time coordinates and clearly relates eight kinds of space-time wave dilations or contractions to shifts in Doppler frequency or wavenumber. Modern physics students may find this approach significantly simplifies and clarifies relativistic physics in space-time (x,ct) and inverse time-space (ω,ck). It resolves some mysteries surrounding super-constant c = 299,792,458 m/s by proving ``Evenson's Axiom'' named in honor of NIST metrologist Ken Evenson (1932-2002) whose spectroscopy established c to start a precision renaissance in spectroscopy and GPS metrology.

  6. Molecular evidence from the nuclear genome for the time frame of human evolution.

    PubMed

    Easteal, S; Herbert, G

    1997-01-01

    Evolutionary divergence times can be inferred from molecular distances if a molecular clock can be assumed and if the substitution rate can be estimated. We present new evidence from relative rate tests that the rate of substitution at fourfold degenerate sites of nuclear genome-coding DNA is uniform in primate and rodent lineages. We also review recent relative rate test results showing substitution rate uniformity in the nuclear genome of simian primates. DNA distances between a range of mammalian taxa shows that a molecular clock is inconsistent with many assumed divergence times irrespective of the assumed substitution rate. We find that the substitution rate that implies the best compromise fit with divergence times across the range of taxa is 2.0-2.25 x 10(-9). This range of substitution rates implies a divergence time of humans and chimpanzees of 4.0-3.6 million years ago. This postdates the occurrence of Ardipithecus ramidus and the earliest occurrence of Australopithecus afarensis, suggesting that the common ancestor of humans and chimpanzees was bipedal and that the trait has been lost in chimpanzees rather than gained in humans.

  7. Student Understanding of Time in Special Relativity: Simultaneity and Reference Frames.

    ERIC Educational Resources Information Center

    Scherr, Rachel E.; Shaffer, Peter S.; Vokos, Stamatis

    2001-01-01

    Reports on an investigation of students' understanding of the concept of time in special relativity. Discusses a series of research tasks to illustrate how student reasoning of fundamental concepts of relativity was probed. Indicates that after standard instruction, students have serious difficulties with the relativity of simultaneity and the…

  8. 15 Years of Terra, 14 Years of Application Usage

    NASA Astrophysics Data System (ADS)

    Schmaltz, J. E.; Alarcon, C.; Boller, R. A.; Cechini, M. F.; Davies, D.; Fu, G.; Gunnoe, T.; Hall, J. R.; Huang, T.; Ilavajhala, S.; Jackson, M.; King, J.; McGann, M.; Murphy, K. J.; Roberts, J. T.; Thompson, C. K.; Ye, G.

    2014-12-01

    The instruments onboard the Terra spacecraft were designed for long-term Earth science research but not long after launch it became apparent that this data and imagery could be made available in near real-time for applications users. During the year 2000 fire season in the western United States, the US Forest Service approached NASA with a request to expedite MODIS fire detections. The Rapid Response system was created to generate fire detections as well as true color imagery in both swath and geo-referenced formats. This imagery was used by a wide variety of applications, such as NASA's AERONET program, the USDA Foreign Agricultural Service, Antarctic resupply shipping, flood mapping for relief agencies, Deepwater Horizon monitoring, volcanic ash monitoring, as well as print, televised, and Internet media. From 2004, the University of Maryland's Web Fire Mapper helped distribute fire detection information in a variety of formats. However, the applications community expressed the need for near-real time access to the underlying data. This requirement led to the development of the Land Atmosphere Near real-time Capability for EOS (Earth Observing System) (LANCE) in 2009. To achieve the latency requirements, many components of the EOS satellite operations, ground and science processing systems had to be made more efficient. In addition, products that require ancillary data were modified to use alternate inputs. Forty Terra MODIS data products are currently available from LANCE. LANCE also includes data from other instruments including AIRS, AMSR-E, MLS, and OMI. To help near-real time users navigate this large data offering, a new imagery service was begun in 2011 - Global Imagery Browse Services (GIBS). This service provides very responsive viewing using the Web Map Tile Service protocol. These programs will continue to support and expand the use of Terra data for near-real time applications well into the future.

  9. Time-Dependent Selection of an Optimal Set of Sources to Define a Stable Celestial Reference Frame

    NASA Technical Reports Server (NTRS)

    Le Bail, Karine; Gordon, David

    2010-01-01

    Temporal statistical position stability is required for VLBI sources to define a stable Celestial Reference Frame (CRF) and has been studied in many recent papers. This study analyzes the sources from the latest realization of the International Celestial Reference Frame (ICRF2) with the Allan variance, in addition to taking into account the apparent linear motions of the sources. Focusing on the 295 defining sources shows how they are a good compromise of different criteria, such as statistical stability and sky distribution, as well as having a sufficient number of sources, despite the fact that the most stable sources of the entire ICRF2 are mostly in the Northern Hemisphere. Nevertheless, the selection of a stable set is not unique: studying different solutions (GSF005a and AUG24 from GSFC and OPA from the Paris Observatory) over different time periods (1989.5 to 2009.5 and 1999.5 to 2009.5) leads to selections that can differ in up to 20% of the sources. Observing, recording, and network improvement are some of the causes, showing better stability for the CRF over the last decade than the last twenty years. But this may also be explained by the assumption of stationarity that is not necessarily right for some sources.

  10. Survival of rock-colonizing organisms after 1.5 years in outer space.

    PubMed

    Onofri, Silvano; de la Torre, Rosa; de Vera, Jean-Pierre; Ott, Sieglinde; Zucconi, Laura; Selbmann, Laura; Scalzi, Giuliano; Venkateswaran, Kasthuri J; Rabbow, Elke; Sánchez Iñigo, Francisco J; Horneck, Gerda

    2012-05-01

    Cryptoendolithic microbial communities and epilithic lichens have been considered as appropriate candidates for the scenario of lithopanspermia, which proposes a natural interplanetary exchange of organisms by means of rocks that have been impact ejected from their planet of origin. So far, the hardiness of these terrestrial organisms in the severe and hostile conditions of space has not been tested over extended periods of time. A first long-term (1.5 years) exposure experiment in space was performed with a variety of rock-colonizing eukaryotic organisms at the International Space Station on board the European EXPOSE-E facility. Organisms were selected that are especially adapted to cope with the environmental extremes of their natural habitats. It was found that some-but not all-of those most robust microbial communities from extremely hostile regions on Earth are also partially resistant to the even more hostile environment of outer space, including high vacuum, temperature fluctuation, the full spectrum of extraterrestrial solar electromagnetic radiation, and cosmic ionizing radiation. Although the reported experimental period of 1.5 years in space is not comparable with the time spans of thousands or millions of years believed to be required for lithopanspermia, our data provide first evidence of the differential hardiness of cryptoendolithic communities in space.

  11. An assessment of the government liquid hydrogen requirements for the 1995-2005 time frame

    NASA Technical Reports Server (NTRS)

    Bain, Addison

    1990-01-01

    The results of government study of long range liquid hydrogen (LH2) requirements for the time period of 1995 through the year 2005 are presented. To assure an adequate supply of LH2 is available in support of various programs, it is imperative a long range projection of LH2 requirements be developed and maintained. This information is vital in planning for necessary procurement actions and assuring adequate industry lead time to acquiring the necessary production and distribution capabilities. The Advanced Launch System and High-Altitude Long-Endurance programs may represent the predominant government needs for LH2 in the long range. The assembled data clearly indicates a need for KSC (Kennedy Space Center) constant program/project surveillance. Also clear is the need for KSC to monitor industry's plans for LH2 plant production and distribution expansion.

  12. The JPL ASTER Volcano Archive: the development and capabilities of a 15 year global high resolution archive of volcano data.

    NASA Astrophysics Data System (ADS)

    Linick, J. P.; Pieri, D. C.; Sanchez, R. M.

    2014-12-01

    The physical and temporal systematics of the world's volcanic activity is a compelling and productive arena for the exercise of orbital remote sensing techniques, informing studies ranging from basic volcanology to societal risk. Comprised of over 160,000 frames and spanning 15 years of the Terra platform mission, the ASTER Volcano Archive (AVA: http://ava.jpl.nasa.gov) is the world's largest (100+Tb) high spatial resolution (15-30-90m/pixel), multi-spectral (visible-SWIR-TIR), downloadable (kml enabled) dedicated archive of volcano imagery. We will discuss the development of the AVA, and describe its growing capability to provide new easy public access to ASTER global volcano remote sensing data. AVA system architecture is designed to facilitate parameter-based data mining, and for the implementation of archive-wide data analysis algorithms. Such search and analysis capabilities exploit AVA's unprecedented time-series data compilations for over 1,550 volcanoes worldwide (Smithsonian Holocene catalog). Results include thermal anomaly detection and mapping, as well as detection of SO2 plumes from explosive eruptions and passive SO2 emissions confined to the troposphere. We are also implementing retrospective ASTER image retrievals based on volcanic activity reports from Volcanic Ash Advisory Centers (VAACs) and the US Air Force Weather Agency (AFWA). A major planned expansion of the AVA is currently underway, with the ingest of the full 1972-present LANDSAT, and NASA EO-1, volcano imagery for comparison and integration with ASTER data. Work described here is carried out under contract to NASA at the Jet Propulsion Laboratory as part of the California Institute of Technology.

  13. Predictors of River Ice Breakup Severity on the Yukon River in Interior Alaska: an Examination of the Past 15 Years

    NASA Astrophysics Data System (ADS)

    van Breukelen, C. M.

    2015-12-01

    On the major interior rivers of Alaska, spring river ice breakup is the single largest annual flood threat and can result in fatalities in addition to millions of dollars of damages. Unlike freeze up, which is a gradual, months-long progression, breakup is a quick process during which an entire winters worth of ice lifts and moves downstream in a short time frame (hours to days). Breakup types range between thermal and dynamic. A thermal breakup is relatively slow; ice degrades in place before moving downstream. A dynamic breakup is quicker; the ice is relatively strong before the breakup front moves past. Severe breakup flooding is typically a result of a dynamic breakup. Because the ice has not yet deteriorated, large, strong sheets of ice become jammed on islands, river bends, or other ice sheets, creating an ice jam. The water levels behind an ice jam can rise rapidly and with little warning. The goal of this study is to better understand predictors of breakup flood severity on the Upper and Middle Yukon River; between Eagle and Nulato, Alaska. We examine end of winter snowpack, ESRL Temperature Reanalysis data, and breakup-related flood observations from 2000 to 2015. Experience has shown that those years which have a large end of winter snowpack and a rapid spring warm-up have an above average chance of flooding, but this study seeks to expand on that knowledge base. What about years where only one of those factors (quick warm up or large snowpack) is present? Also, are there cases of years where the April antecedent conditions were similar, but the outcome of breakup was different? Why? Is flooding at a certain location an indicator that there will be flooding at another location downstream? This study is an in-depth examination of the past 15 years of breakup on the Yukon. A better understanding of these past events will lead to greater skill at predicting future events, and a better service for our stakeholders.

  14. Stopping time: Henry Fox Talbot and the origins of freeze-frame photography.

    PubMed

    Ramalingam, Chitra

    2008-09-01

    As an image-making tool for scientists studying the transient, instantaneous photography has long been seen as opening up a visual realm previously inaccessible to the inferior testimony of the human eye. But when photographic pioneer Henry Fox Talbot took the first photograph of a moving object by the light of an electric spark in 1851, he was guided by existing visual practices designed to create instantaneous vision in the eye itself. Exploring the background behind the peculiar subject of his experiment - a mechanically spinning disc - reveals a hidden prehistory of spark-illuminated photography: physicists' pre-photographic techniques for stopping time.

  15. MODVOLC: 15 years of autonomous observations of Earth's erupting volcanoes

    NASA Astrophysics Data System (ADS)

    Wright, Robert

    2015-04-01

    During the period 28 February 2000 and 31 December 2014, the MODVOLC system (http://modis.higp.hawaii.edu) has autonomously analyzed almost 9 trillion pixels contained with almost three million MODIS images, searching for evidence of high temperature thermal signatures associated with volcanic eruptions, and making the results available via the internet. Thermal unrest, mainly associated with active lava, be it in the form of flows, domes, lakes, or confined to vents, has been detected at 96 volcanoes during this period of time. This presentation reviews some important results that have been obtained using this data set.

  16. Nonlinear finite element model updating of an infilled frame based on identified time-varying modal parameters during an earthquake

    NASA Astrophysics Data System (ADS)

    Asgarieh, Eliyar; Moaveni, Babak; Stavridis, Andreas

    2014-11-01

    A model updating methodology is proposed for calibration of nonlinear finite element (FE) models simulating the behavior of real-world complex civil structures subjected to seismic excitations. In the proposed methodology, parameters of hysteretic material models assigned to elements (or substructures) of a nonlinear FE model are updated by minimizing an objective function. The objective function used in this study is the misfit between the experimentally identified time-varying modal parameters of the structure and those of the FE model at selected time instances along the response time history. The time-varying modal parameters are estimated using the deterministic-stochastic subspace identification method which is an input-output system identification approach. The performance of the proposed updating method is evaluated through numerical and experimental applications on a large-scale three-story reinforced concrete frame with masonry infills. The test structure was subjected to seismic base excitations of increasing amplitude at a large outdoor shake-table. A nonlinear FE model of the test structure has been calibrated to match the time-varying modal parameters of the test structure identified from measured data during a seismic base excitation. The accuracy of the proposed nonlinear FE model updating procedure is quantified in numerical and experimental applications using different error metrics. The calibrated models predict the exact simulated response very accurately in the numerical application, while the updated models match the measured response reasonably well in the experimental application.

  17. Methods and Measures Used for Follow-up at 15 Years of the English and Romanian Adoptee (ERA) Study

    ERIC Educational Resources Information Center

    Monographs of the Society for Research in Child Development, 2010

    2010-01-01

    This chapter covers the methods and measures used in the ERA study, with a special focus on age 15 outcomes. First, the authors outline the sample participation rate for the 15-year follow-up--the percentages in all cases referring to the numbers at the time of initial sample contact. They then describe the measures used in this monograph,…

  18. A look at global seismicity during 1999 in the longer-term time frame

    NASA Astrophysics Data System (ADS)

    Marza, Vasile; Carvalho, Juraci; Barros, Lucas; Chimpliganond, Cristiano

    An analysis and discussion of the main features and effects of the 1999global seismicity based especially on the inferred patterns of strong(Mw 7) earthquakes using NEIC/USGS data is presented.Based on the above data and their statistical features (see also Table 1)one may state that from the point of view of occurrence rate (number/yr)the 1999 global seismicity was fairly regular, but from the moment (orenergy) release standpoint it is well under the long-term average. The spacepartition was again rather typical and time distribution was quasi-Poissonian,noteworthy, the 1999 worldwide seismicity had an anomalously high deathtoll, to be discussed later. Two main new insights are brought by ouranalysis: (i) a (mega)quiescence along the whole south American segmentof circum-Pacific earthquake belt, which was inferred and rated asanomalous while it was underway and which, in retrospect, ended with thegreat (Mw = 8.4 HRV) 2001 Arequipa (Peru) event; (ii) an intriguingmonotonous rate decrease within only magnitude class 5.0 to 5.9 duringthe analyzed period (i.e., 1990-1999).

  19. The 2-MEV model: Constancy of adolescent environmental values within an 8-year time frame

    NASA Astrophysics Data System (ADS)

    Bogner, F. X.; Johnson, B.; Buxner, S.; Felix, L.

    2015-08-01

    The 2-MEV model is a widely used tool to monitor children's environmental perception by scoring individual values. Although the scale's validity has been confirmed repeatedly and independently as well as the scale is in usage within more than two dozen language units all over the world, longitudinal properties still need clarification. The purpose of the present study therefore was to validate the 2-MEV scale based on a large data basis of 10,676 children collected over an eight-year period. Cohorts of three different US states contributed to the sample by responding to a paper-and-pencil questionnaire within their pre-test initiatives in the context of field center programs. Since we used only the pre-program 2-MEV scale results (which is before participation in education programs), the data were clearly unspoiled by any follow-up interventions. The purpose of analysis was fourfold: First, to test and confirm the hypothesized factorized structure for the large data set and for the subsample of each of the three states. Second, to analyze the scoring pattern across the eight years' time range for both preservation and utilitarian preferences. Third, to investigate any age effects in the extracted factors. Finally, to extract suitable recommendations for educational implementation efforts.

  20. Community-acquired intracranial suppurative infections: A 15-year report

    PubMed Central

    Yıldırmak, Taner; Gedik, Habip; Şimşek, Funda; Kantürk, Arzu

    2014-01-01

    Background: The aim of this study was to retrospectively evaluate the characteristics, treatment, and prognosis of patients with intracranial suppurative infection (ISI) by review of clinical, radiological, and laboratory findings. Methods: The data collected from all patients who had been diagnosed with ISI and followed up at the Infectious Diseases and Clinical Microbiology Department of the study site between 1998 and 2013 were reviewed. Results: Of the 23 ISI patients identified, the mean age was 38.21 ± 12.61 years (range: 19–67 years, median: 34) and mean symptom duration was 22.25 ± 20.22 days. Headache was the most common symptom, the frontal lobe the most common localization of ISI, and mastoiditis due to chronic suppurative otitis media the most common source of infection causing ISI. Proteus mirabilis, Pseudomonas spp., Peptostreptococcus spp., Enterococcus avium, Mycobacterium tuberculosis complex, and Toxoplasma gondii were isolated from the specimens collected from 6 (37.5%) of the 16 patients who underwent invasive procedures. Of these 16 patients, 2 underwent craniotomy, 12 burr hole aspiration, and 2 stereotactic biopsy. The rate of recurrence was 0% and the rates of sequelae and fatality were both 8%. Conclusions: ISI should be considered in male patients presenting with headache and neurological signs and symptoms, whether with or without fever, on admission for early diagnosis and provision of timely, adequate therapy and, if required, surgical intervention to reduce mortality and sequelae rates. PMID:25317357

  1. Teaching, Practice, Feedback: 15 years of COMPASS science communication training

    NASA Astrophysics Data System (ADS)

    Neeley, L.; Smith, B.; McLeod, K.; English, C. A.; Baron, N.

    2014-12-01

    COMPASS is focused on helping scientists build the skills and relationships they need to effectively participate in public discourse. Founded in 2001 with an emphasis on ocean science, and since expanding to a broader set of environmental sciences, we have advised, coached, and/or trained thousands of researchers of all career stages. Over the years, our primary work has notably shifted from needing to persuade scientists why communication matters to supporting them as they pursue the question of what their communication goals are and how best to achieve them. Since our earliest forays into media promotion, we have evolved with the state of the science communication field. In recent years, we have adapted our approach to one that facilitates dialogue and encourages engagement, helps scientists identify the most relevant people and times to engage, tests our own assumptions, and incorporates relevant social science as possible. In this case study, we will discuss more than a decade of experience in helping scientists find or initiate and engage in meaningful conversations with journalists and policymakers.

  2. Familial cardiomyopathy--a 15-year follow-up.

    PubMed

    Rosenqvist, M; Biörck, G; de Faire, U; Freyschuss, U; Lindvall, K; Magnusson, B

    1980-01-01

    In 1961--1962 five families including 53 members with a familial form of cardiomyopathy (CMP) were examined. Fifteen years later a reinvestigation of the previously examined families was carried out using community registers; mortality as well as new family members were registered. Another 50 family members were thereby added. Three out of 6 young subjects who were diagnosed as having definite (2) or suspected (1) CMP at the initial examination died during the follow-up period. Four of the five families, totalling 39/41 members, were given a thorough noninvasive clinical examination including ECG, phonocardiogram exercise test, measurement of systolic time intervals and carotid arterial pulse curves, and echocardiography (Echo). A high number (17/39) of suspected or definite pathologic echocardiographic changes consistent with CMP was observed on reinvestigation. Eleven of these 17 were asymptomatic. Except for Echo, the non-invasive methods used in this study did not contribute to the diagnosis of CMP, but the non-Echo methods confirmed the Echo findings in those patients with symptoms of cardiac disease. The four reexamined families revealed a very heterogenous pattern of CMP, with both symmetric and asymmetric hypertrophy (ratio symmetric/asymmetric = 15 : 2). It may be questioned whether asymptomatic subjects with borderline changes, indicative of symmetric hypertrophy, will develop definite symmetric CMP or whether their symptoms constitute an early stage of asymmetric CMP. Echocardiographic findings may well fit with the theory of a dominant mode of inheritance.

  3. Perceptual frames in frequency estimation.

    PubMed

    Zyłowska, Aleksandra; Kossek, Marcin; Wawrzyniak, Małgorzata

    2014-02-01

    This study is an introductory investigation of cognitive frames, focused on perceptual frames divided into information and formal perceptual frames, which were studied based on sub-additivity of frequency estimations. It was postulated that different presentations of a response scale would result in different percentage estimates of time spent watching TV or using the Internet. The results supported the existence of perceptual frames that influence the perception process and indicated that information perceptual frames had a stronger effect than formal frames. The measures made possible the exploration of the operation of perceptual frames and also outlined the relations between heuristics and cognitive frames. PMID:24765715

  4. A magnetostratigraphic time frame for Plio-Pleistocene transgressions in the South Caspian Basin, Azerbaijan

    NASA Astrophysics Data System (ADS)

    Van Baak, C. G. C.; Vasiliev, I.; Stoica, M.; Kuiper, K. F.; Forte, A. M.; Aliyeva, E.; Krijgsman, W.

    2013-04-01

    The isolation of the Caspian Sea took place in the latest Miocene coinciding with a significant lowering of sea level and the deposition of a massive lowstand deltaic system. This so-called Productive Series is the main reservoir unit of the South Caspian oil-province. The Productive Series is overlain by marine clays from the Akchagylian and Apsheronian regional stages. During the Plio-Pleistocene, the Caspian basin experienced several short periods of intermittent connectivity with other marine basins. This work aims to create integrated, high-resolution, bio-magnetostratigraphic dating of these regional transgressions in key sections of the South Caspian Basin in Azerbaijan. We sample two long sections, the Lokbatan section in the Palaeo-Volga delta and the Xocashen section in the Kura Basin. Palaeoenvironmental reconstructions are derived from characteristic ostracod species. Rock magnetic analyses combined with thermal demagnetisation data indicate that the magnetic signal is carried dominantly by the iron oxide magnetite in the Productive Series of Lokbatan section and in the Xocashen section. The marine Akchagylian and Apsheronian of Lokbatan are characterised by the iron sulphide greigite, which appears to be of (near-) primary origin. The most logical correlation of the magnetic polarity patterns to the Geomagnetic Polarity Time Scale dates the Akchagylian transgression at ~ 3.2 Ma, a major transgression during the Apsheronian at ~ 2.0 Ma and the Bakunian transgression at 0.85-0.89 Ma. Ostracod assemblages indicate increasing salinities during these transgressions, from fresh water lacustrine to brackish-marine species. This implies that marine connections have been created with an adjacent basin that has a higher salinity, most likely the Black Sea.

  5. Moving Forward in Space and Time: How Strong is the Conceptual Link between Spatial and Temporal Frames of Reference?

    PubMed Central

    Bender, Andrea; Rothe-Wulf, Annelie; Hüther, Lisa; Beller, Sieghard

    2012-01-01

    People often use spatial vocabulary to describe temporal relations, and this increasingly has motivated attempts to map spatial frames of reference (FoRs) onto time. Recent research suggested that speech communities, which differ in how they conceptualize space, may also differ in how they conceptualize time and, more specifically, that the preferences for spatial FoRs should carry over to the domain of time. Here, we scrutinize this assumption (a) by reviewing data from recent studies on temporal references, (b) by comparing data we had collected in previous studies on preferences for spatial and temporal FoRs in four languages, (c) by analyzing new data from dynamic spatial tasks that resemble the temporal tasks more closely, and (d) by assessing the co-variation of individual preferences of English speakers across space and time. While the first set of data paints a mixed picture, the latter three do not support the assumption of a close link between referencing preferences across domains. We explore possible reasons for this lack of consistency and discuss implications for research on temporal references. PMID:23162519

  6. Taming the escape dynamics of nonadiabatic time-periodically driven quantum dissipative system within the frame of Wigner formalism

    NASA Astrophysics Data System (ADS)

    Shit, Anindita; Chattopadhyay, Sudip; Ray Chaudhuri, Jyotipratim

    2014-03-01

    Escape under the action of the external modulation constitutes a nontrivial generalization of an conventional Kramers rate because the system is away from thermal equilibrium. A derivation of this result from the point of view of Langevin dynamics in the frame of Floquet theorem in conjunction with the Kapitza-Landau time window (that leads to an attractive description of the time-dependent quantum dynamics in terms of time-independent one) has been provided. The quantum escape rate in the intermediate-to-high and very-high damping regime so obtained analytically using the phase space formalism associated with the Wigner distribution and path-integral formalism bears a quantum correction that depends strongly on the barrier height. It is shown that an increase of (amplitude/frequency) ratio causes the system to decay faster, in general. The crossover temperature between tunneling and thermal activation increases in the presence of field so that quantum effects in the escape are relevant at higher temperatures.

  7. Brief Report: Pregnant by Age 15 Years and Substance Use Initiation among US Adolescent Girls

    ERIC Educational Resources Information Center

    Cavazos-Rehg, Patricia A.; Krauss, Melissa J.; Spitznagel, Edward L.; Schootman, Mario; Cottler, Linda B.; Bierut, Laura Jean

    2012-01-01

    We examined substance use onset and associations with pregnancy by age 15 years. Participants were girls ages 15 years or younger (weighted n = 8319) from the 1999-2003 Youth Risk Behavior Surveillance System (YRBS). Multivariable logistic regression examined pregnancy as a function of substance use onset (i.e., age 10 years or younger, 11-12,…

  8. Deliberate Self-Harm by under-15-Year-Olds: Characteristics, Trends and Outcome

    ERIC Educational Resources Information Center

    Hawton, Keith; Harriss, Louise

    2008-01-01

    Background: Relatively little information is available about the characteristics and long-term outcome of children and adolescents aged under 15 years who present to general hospitals because of deliberate self-harm (DSH). Method: Information was collected on 710 consecutive under-15-year-olds presenting to a general hospital in central England…

  9. 29 CFR 570.33 - Prohibited occupations for minors 14 and 15 years of age.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Prohibited occupations for minors 14 and 15 years of age... minors 14 and 15 years of age. Link to an amendment published at 75 FR 28448, May 20, 2010. This subpart... revised text is set forth as follows: § 570.33 Occupations that are prohibited to minors 14 and 15...

  10. Using expert knowledge and modeling to define mangrove composition, functioning, and threats and estimate time frame for recovery.

    PubMed

    Mukherjee, Nibedita; Sutherland, William J; Khan, Md Nabiul I; Berger, Uta; Schmitz, Nele; Dahdouh-Guebas, Farid; Koedam, Nico

    2014-06-01

    Mangroves are threatened worldwide, and their loss or degradation could impact functioning of the ecosystem. Our aim was to investigate three aspects of mangroves at a global scale: (1) their constituents (2) their indispensable ecological functions, and (3) the maintenance of their constituents and functions in degraded mangroves. We focused on answering two questions: "What is a mangrove ecosystem" and "How vulnerable are mangrove ecosystems to different impacts"? We invited 106 mangrove experts globally to participate in a survey based on the Delphi technique and provide inputs on the three aspects. The outputs from the Delphi technique for the third aspect, i.e. maintenance of constituents and functions were incorporated in a modeling approach to simulate the time frame for recovery. Presented here for the first time are the consensus definition of the mangrove ecosystem and the list of mangrove plant species. In this study, experts considered even monospecific (tree) stands to be a mangrove ecosystem as long as there was adequate tidal exchange, propagule dispersal, and faunal interactions. We provide a ranking of the important ecological functions, faunal groups, and impacts on mangroves. Degradation due to development was identified as having the largest impact on mangroves globally in terms of spatial scale, intensity, and time needed for restoration. The results indicate that mangroves are ecologically unique even though they may be species poor (from the vegetation perspective). The consensus list of mangrove species and the ranking of the mangrove ecological functions could be a useful tool for restoration and management of mangroves. While there is ample literature on the destruction of mangroves due to aquaculture in the past decade, this study clearly shows that more attention must go to avoiding and mitigating mangrove loss due to coastal development (such as building of roads, ports, or harbors). PMID:25360265

  11. Using expert knowledge and modeling to define mangrove composition, functioning, and threats and estimate time frame for recovery.

    PubMed

    Mukherjee, Nibedita; Sutherland, William J; Khan, Md Nabiul I; Berger, Uta; Schmitz, Nele; Dahdouh-Guebas, Farid; Koedam, Nico

    2014-06-01

    Mangroves are threatened worldwide, and their loss or degradation could impact functioning of the ecosystem. Our aim was to investigate three aspects of mangroves at a global scale: (1) their constituents (2) their indispensable ecological functions, and (3) the maintenance of their constituents and functions in degraded mangroves. We focused on answering two questions: "What is a mangrove ecosystem" and "How vulnerable are mangrove ecosystems to different impacts"? We invited 106 mangrove experts globally to participate in a survey based on the Delphi technique and provide inputs on the three aspects. The outputs from the Delphi technique for the third aspect, i.e. maintenance of constituents and functions were incorporated in a modeling approach to simulate the time frame for recovery. Presented here for the first time are the consensus definition of the mangrove ecosystem and the list of mangrove plant species. In this study, experts considered even monospecific (tree) stands to be a mangrove ecosystem as long as there was adequate tidal exchange, propagule dispersal, and faunal interactions. We provide a ranking of the important ecological functions, faunal groups, and impacts on mangroves. Degradation due to development was identified as having the largest impact on mangroves globally in terms of spatial scale, intensity, and time needed for restoration. The results indicate that mangroves are ecologically unique even though they may be species poor (from the vegetation perspective). The consensus list of mangrove species and the ranking of the mangrove ecological functions could be a useful tool for restoration and management of mangroves. While there is ample literature on the destruction of mangroves due to aquaculture in the past decade, this study clearly shows that more attention must go to avoiding and mitigating mangrove loss due to coastal development (such as building of roads, ports, or harbors).

  12. Using expert knowledge and modeling to define mangrove composition, functioning, and threats and estimate time frame for recovery

    PubMed Central

    Mukherjee, Nibedita; Sutherland, William J; Khan, Md Nabiul I; Berger, Uta; Schmitz, Nele; Dahdouh-Guebas, Farid; Koedam, Nico

    2014-01-01

    Mangroves are threatened worldwide, and their loss or degradation could impact functioning of the ecosystem. Our aim was to investigate three aspects of mangroves at a global scale: (1) their constituents (2) their indispensable ecological functions, and (3) the maintenance of their constituents and functions in degraded mangroves. We focused on answering two questions: “What is a mangrove ecosystem” and “How vulnerable are mangrove ecosystems to different impacts”? We invited 106 mangrove experts globally to participate in a survey based on the Delphi technique and provide inputs on the three aspects. The outputs from the Delphi technique for the third aspect, i.e. maintenance of constituents and functions were incorporated in a modeling approach to simulate the time frame for recovery. Presented here for the first time are the consensus definition of the mangrove ecosystem and the list of mangrove plant species. In this study, experts considered even monospecific (tree) stands to be a mangrove ecosystem as long as there was adequate tidal exchange, propagule dispersal, and faunal interactions. We provide a ranking of the important ecological functions, faunal groups, and impacts on mangroves. Degradation due to development was identified as having the largest impact on mangroves globally in terms of spatial scale, intensity, and time needed for restoration. The results indicate that mangroves are ecologically unique even though they may be species poor (from the vegetation perspective). The consensus list of mangrove species and the ranking of the mangrove ecological functions could be a useful tool for restoration and management of mangroves. While there is ample literature on the destruction of mangroves due to aquaculture in the past decade, this study clearly shows that more attention must go to avoiding and mitigating mangrove loss due to coastal development (such as building of roads, ports, or harbors). PMID:25360265

  13. The 15-Year Evolution of the Thoracoscopic Anterior Release: Does It Still Have a Role?

    PubMed Central

    Arunakul, Rattalerk; Peterson, Alex; Bartley, Carrie E.; Cidambi, Krishna R.; Varley, Eric S.

    2015-01-01

    Study Design Retrospective. Purpose To determine how the indications for anterior thoracoscopic release and fusion have evolved over time. Overview of Literature Anterior release was commonly performed to correct severe spinal deformities before the advent of pedicle screw fixation. The thoracoscopic approach significantly reduced the morbidity, as compared to open thoracotomy procedures. Methods We reviewed charts and radiographs of pediatric spinal deformity patients who underwent thoracoscopic release/fusion for their deformity from 1994 to 2008. Indications for the thoracoscopic procedure were assigned to one of the following categories: hyperkyphosis, large/stiff scoliosis, crankshaft prevention, and 'other'. We analysed indications grouped in 3-year intervals to determine how the indications for this procedure evolved over the past 15 years. Results One hundred and thirty-eight patients (mean age, 15 years; range, 2-28 years) underwent the procedure, with 160 identified indications. The frequency of thoracoscopic anterior release/fusion decreased after peaking in the years 2000-2002. Initially, hyperkyphosis was the most frequent indication (15/33, 45%; 1994-1996), but declined to an intermittent indication since 2006. The use of thoracoscopy to prevent crankshaft has also declined, but remains an indication for the most immature cases (2/17, 12%; 2006-2008). Severe or rigid scoliosis is currently the most common indication for thoracoscopic release/fusion at our center (11/17, 65%; 2006-2008). Conclusions The indications for a thoracoscopic anterior release/fusion has evolved with our increased understanding of this procedure and improved posterior fixation with pedicle screw instrumentation. Thoracoscopy in select spinal deformity patients still has an important role despite its less frequent use, as compared to the past decade. PMID:26240714

  14. Using the Advanced Progressive Matrices (Set I) to Assess Fluid Ability in a Short Time Frame: An Item Response Theory-Based Analysis

    ERIC Educational Resources Information Center

    Chiesi, Francesca; Ciancaleoni, Matteo; Galli, Silvia; Primi, Caterina

    2012-01-01

    This article is aimed at evaluating the possibility that Set I of the Advanced Progressive Matrices (APM-Set I) can be employed to assess fluid ability in a short time frame. The APM-Set I was administered to a sample of 1,389 primary and secondary school students. Confirmatory factor analysis attested to the unidimensionality of the scale. Item…

  15. Persistence of artificial sweeteners in a 15-year-old septic system plume

    NASA Astrophysics Data System (ADS)

    Robertson, W. D.; Van Stempvoort, D. R.; Solomon, D. K.; Homewood, J.; Brown, S. J.; Spoelstra, J.; Schiff, S. L.

    2013-01-01

    SummaryGroundwater contamination from constituents such as NO3-, often occurs where multiple sources are present making source identification difficult. This study examines a suite of major ions and trace organic constituents within a well defined septic system plume in southern Ontario, Canada (Long Point site) for their potential use as wastewater tracers. The septic system has been operating for 20 years servicing a large, seasonal-use campground and tritium/helium age dating indicates that the 200 m long monitored section of the plume is about 15 years old. Four parameters are elevated along the entire length of the plume as follows; the mean electrical conductivity value (EC) in the distal plume zone is 926 μS/cm which is 74% of the mean value below the tile bed, Na+ (14.7 mg/L) is 43%, an artificial sweetener, acesulfame (12.1 μg/L) is 23% and Cl- (71.5 mg/L) is 137%. EC and Cl- appear to be affected by dispersive dilution with overlying background groundwater that has lower EC but has locally higher Cl- as result of the use of a dust suppressant (CaCl2) in the campground. Na+, in addition to advective dilution, could be depleted by weak adsorption. Acesulfame, in addition to the above processes could be influenced by increasing consumer use in recent years. Nonetheless, both Na+ and acesulfame remain elevated throughout the plume by factors of more than 100 and 1000 respectively compared to background levels, and are strong indicators of wastewater impact at this site. EC and Cl- are less useful because their contrast with background values is much less (EC) or because other sources are present (Cl-). Nutrients (NO3-, NH4+, PO43-, K+) and pathogens (Escherichia coli) do not persist in the distal plume zone and are less useful as wastewater indicators here. The artificial sweetener, acesulfame, has persisted at high concentrations in the Long Point plume for at least 15 years (and this timing agrees with tritium/helium-3 dating) and this compound likely

  16. ALH84001: The Key to Unlocking Secrets About Mars-15 Years and Counting

    NASA Technical Reports Server (NTRS)

    Gibson, Everett K.; McKay, D. S.; Thomas-Keprta, K. L.; Clemett, S. J.

    2011-01-01

    From the December 27, 1984 discovery of ALH84001, and its subsequent identification as a sample of Mars in 1993, mystery and debate has surrounded the meteorite [1]. With the realization that the ALH84001 sample was a orthopyroxenite and one of the oldest SNC meteorites (approx.4.09 Ga) [2] available to study, important and critical information about the Martian hydrosphere and atmosphere along with the early history and evolution of the planet could be obtained by studying the unique carbonate globules (approx.3.9 Ga) in the sample [3]. The initial work showed the carbonate globules were deposited within fractures and cracks in the host-orthopyroxene by low-temperature aqueous fluids [4]. Ideas that the carbonates were formed at temperatures [5] approaching 800 C were ruled out by later experiments [6]. The 1996 announcement by McKay et al. [7] that ALH84001 contained features which could be interpreted as having a biogenic origin generated considerable excitement and criticism. The NASA Administrator Dan Golden said the 1996 ALH84001 announcement saved NASAs Mars planetary exploration program and injected $6 billion dollars over five years into the scientific research and analysis efforts [8]. All of the original four lines of evidence for possible biogenic features within ALH84001 offered by McKay et al. have withstood the test of time. Criticism has been directed at the interpretation of the 1996 analytical data. Research has expanded to other SNC meteorites. Despite the numerous attacks on the ideas, the debate continues after 15 years. The 2009 paper by Thomas-Keprta et al. [9] on the origins of a suite of magnetites within the ALH84001 has offered strong arguments that some of the magnetites can only be formed by biogenic processes and not from thermal decomposition or shock events which happened to the meteorite. NASA s Astrobiology Institute was formed from the foundation laid by the ALH84001 hypothesis of finding life beyond the Earth. The strong

  17. Monitoring the state of vegetation in Hungary using 15 years long MODIS Data

    NASA Astrophysics Data System (ADS)

    Kern, Anikó; Bognár, Péter; Pásztor, Szilárd; Barcza, Zoltán; Timár, Gábor; Lichtenberger, János; Ferencz, Csaba

    2015-04-01

    emphasis on drought and heat waves. Te relationship between anomalies of vegetation characteristics and crop yield decrease in agricultural regions were characterised as well. The mean NDVI values of Hungary during the 15 years reveal the behaviour of the vegetation in the country, where the main land cover types (forest, agriculture and grassland) were distinguished as well. NDVI anomalies are analyzed separately for the main land cover types. Deviations from the potential maximum vegetation greenness are also calculated for the entire time period.

  18. Externalizing Behavior and Substance Use Related Problems at 15 Years in Prenatally Cocaine Exposed Adolescents

    PubMed Central

    Min, Meeyoung O.; Minnes, Sonia; Lang, Adelaide; Weishampel, Paul; Short, Elizabeth J.; Yoon, Susan; Singer, Lynn T.

    2014-01-01

    The effect of prenatal cocaine exposure (PCE) on externalizing behavior and substance use related problems at 15 years of age was examined. Participants consisted of 358 adolescents (183 PCE, 175 non-cocaine exposed (NCE)), primarily African-American and of low socioeconomic status, prospectively enrolled in a longitudinal study from birth. Regression analyses indicated that the amount of PCE was associated with higher externalizing behavioral problems (β=.15, p=.02). Adolescents with PCE were also 2.8 times (95% CI=1.38–5.56) more likely to have substance use related problems than their NCE counterparts. No differences between PCE adolescents in non-kinship adoptive or foster care (n=44) and PCE adolescents in maternal/relative care (n=139) were found in externalizing behavior or in the likelihood of substance use related problems. Findings demonstrate teratologic effects of PCE persisting into adolescence. PCE is a reliable marker for the potential development of problem behaviors in adolescence, including substance use related problems. PMID:24636687

  19. Chronicling an Era: 15 Years of SN 1987A with Chandra

    NASA Astrophysics Data System (ADS)

    Frank, Kari A.; Burrows, David N.

    2015-01-01

    Due to its close proximity, the remnant of SN 1987A is the only supernova remnant in which we can study the early developmental stages in detail, providing insight into stellar evolution, the mechanisms of the supernova explosion, and the transition from supernova to supernova remnant as the debris begins to interact with the surrounding CSM. We present here 15 years of X-ray observations with Chandra, including 4 new observations. The X-ray emission traces the progress of the blast wave and functions as a probe of the CSM. About 5000 days after the explosion, the blast wave began impacting the fringes of a dense equatorial ring. With Chandra, we are able to resolve this ring in X-ray images and monitor how it changes over time. We measure the apparent expansion rate of the ring, finding a sudden decrease in the velocity, from ~9000 km/s to ~2000 km/s, as the blast wave impacted the main body of the ring near day 5700. The soft X-ray flux has steadily increased, indicating the blast wave has continued to move through dense material. However, the latest observations suggest the flux has leveled off, a sign that the blast wave may be exiting the ring and on the verge of illuminating the previously unseen material beyond.

  20. Migratory Pathways and Connectivity in Asian Houbara Bustards: Evidence from 15 Years of Satellite Tracking

    PubMed Central

    Combreau, Olivier; Riou, Samuel; Judas, Jacky; Lawrence, Mark; Launay, Frédéric

    2011-01-01

    Information on migratory pathways and connectivity is essential to understanding population dynamics and structure of migrant species. Our manuscript uses a unique dataset, the fruit of 103 individual Asian houbara bustards captured on their breeding grounds in Central Asia over 15 years and equipped with satellite transmitters, to provide a better understanding of migratory pathways and connectivity; such information is critical to the implementation of biologically sound conservation measures in migrant species. At the scale of the distribution range we find substantial migratory connectivity, with a clear separation of migration pathways and wintering areas between western and eastern migrants. Within eastern migrants, we also describe a pattern of segregation on the wintering grounds. But at the local level connectivity is weak: birds breeding within the limits of our study areas were often found several hundreds of kilometres apart during winter. Although houbara wintering in Arabia are known to originate from Central Asia, out of all the birds captured and tracked here not one wintered on the Arabian Peninsula. This is very likely the result of decades of unregulated off-take and severe habitat degradation in this area. At a time when conservation measures are being implemented to safeguard the long-term future of this species, this study provides critical data on the spatial structuring of populations. PMID:21687684

  1. Serum triiodothyronine 7-15 years after fractionated low dose radioiodine therapy of thyrotoxicosis.

    PubMed

    Herrmann, J; Schaps, D; Rusche, H J; Berger, M; Krüskemper, H L; von zur Hühlen, A; Hackenberg, K; Reinwein, D

    1975-03-01

    In 189 of 334 patients, who had been treated with fractionated doses of radioiodine for Graves' disease 7-15 years ago, the serum concentrations of triiodothyronine have been estimated in additition to the following parameters: Protein bound 127-iodine (PB-127-I), free thyroxine index, cholesterol- and TSH-level in serum, tendon reflex time and clinical index according to Billewitz et al. (1969). In forty-one of the 189 sera the free T4 (AFT4) and free T3 (AFT3) concentrations were measured as well. The following hormonal and clinical patterns were observed: (1) Euthyroidism, with all parameters within the normal range in 148 patients (equals 78-4%). (2) Hypothyroidism with low serum T3, PBI, AFT4, AFT3 and elevated TSH six subjects (equals 3-2%). (3) Persistent hyperthyroidism with increased thyroid hormone concentrations and low TSH in seven cases (equals 3-7%). (4) In twenty-eight clinically euthyroid patients (equals 14-8%) TSH was elevated with normal PBI and AFT4. Twenty of these subjects had a low normal T3 and in nine the T3 was clearly in the hypothyroid range (40 plus or minus 12 mug/dl). (5) The constellation of normal T3, low T4 and elevated TSH, which has been frequently found after radioiodine therapy, has been seen in only moderate form in ten cases.

  2. Past 15-Year Trends in Adolescent Marijuana Use: Differences by Race/Ethnicity and Sex

    PubMed Central

    Johnson, Renee M.; Fairman, Brian; Gilreath, Tamika; Xuan, Ziming; Rothman, Emily F.; Parnham, Taylor; Furr-Holden, C. Debra M.

    2015-01-01

    Background The potential for increases in adolescent marijuana use is an important concern given recent changes in marijuana policy. The purpose of this study was to estimate trends in marijuana use from 1999-2013 among a national sample of US high school students. We examine changes over time by race/ethnicity and sex. Methods Data are from the National Youth Risk Behavior Survey (YRBS), which involves biennial, school-based surveys that generate nationally-representative data about 9th-12th grade students in the United States. Students self-reported sex, race/ethnicity, and marijuana use (i.e., lifetime use, current use, any use before age 13). We generated national estimates of the prevalence of marijuana use for the time period, and also tested for linear and quadratic trends (n=115,379). Results The prevalence of lifetime marijuana use decreased modestly from 1999 to 2009 (44% to 37%), and has increased slightly since 2009 (41%). Other marijuana use variables (e.g., past 30-day use) followed a similar pattern over time. The prevalence of past 30-day use from 1999-2013 for all groups and both sexes was 22.5%, and it was lowest among Asians and highest among American Indian/Alaska Natives. Although boys have historically had a higher prevalence of marijuana use, results indicate that male-female differences in marijuana use decreased over time. Conclusion Despite considerable changes in state marijuana policies over the past 15 years, marijuana use among high school students has largely declined. Continued surveillance is needed to assess the impact of policy changes on adolescent marijuana use. PMID:26361714

  3. Positive parenting mitigates the effects of poor self-regulation on BMI trajectories from age 4 to 15 years

    PubMed Central

    Connell, Lauren E.; Francis, Lori A.

    2014-01-01

    Objective This study sought to determine whether parenting style moderated the effects of delay of gratification on BMI trajectories from age 4 to 15 years. Methods Longitudinal data were analyzed on 778 children drawn from the Study of Early Child Care and Youth Development. Parenting style (authoritative, authoritarian, permissive, neglectful) was created from measures of mothers’ sensitivity and expectations for self-control when children were age 4 years. Self-regulation was also measured at 4 years using a well-known delay of gratification protocol. BMI was calculated from measured height and weight at each time point. Mixed modeling was used to test the interaction of parenting styles and ability to delay gratification on BMI trajectories from 4 to 15 years. Results There was a significant interaction effect of parenting and ability to delay on BMI growth from 4 to 15 years for boys. Boys who had authoritarian mothers and failed to delay gratification had a significantly steeper rate of growth in BMI from childhood through adolescence than children in any other parenting x delay group. Conclusions Authoritative and permissive parenting styles were protective against more rapid BMI gains for boys who could not delay gratification. Ability to delay gratification was protective against BMI gains for boys who had parents with authoritarian or neglectful parenting styles. PMID:23977874

  4. Factors Associated With Kyphosis Progression in Older Women: 15 years experience in the Study of Osteoporotic Fractures

    PubMed Central

    Kado, DM; Huang, MH; Karlamangla, AS; Cawthon, P; Katzman, W; Hillier, TA; Ensrud, K; Cummings, SR

    2012-01-01

    Age-related hyperkyphosis is thought to be a result of underlying vertebral fractures, but studies suggest that among the most hyperkyphotic women, only one in three have underlying radiographic vertebral fractures. Although commonly observed, there is no widely accepted definition of hyperkyphosis in older persons, and other than vertebral fracture, no major causes have been identified. To identify important correlates of kyphosis and risk factors for its progression over time, we conducted a 15 year retrospective cohort study of 1,196 women, aged 65 years and older at baseline (1986–88), from four communities across the United States: Baltimore County, MD; Minneapolis, MN, Portland, Oregon, and the Monongahela Valley, PA. Cobb angle kyphosis was measured from radiographs obtained at baseline and an average of 3.7 and 15 years later. Repeated measures, mixed effects analyses were performed. At baseline, the mean kyphosis angle was 44.7 degrees (standard error 0.4, standard deviation 11.9) and significant correlates included a family history of hyperkyphosis, prevalent vertebral fracture, low bone mineral density, greater body weight, degenerative disc disease, and smoking. Over an average of 15 years, the mean increase in kyphosis was 7.1 degrees (standard error 0.25). Independent determinants of greater kyphosis progression were prevalent and incident vertebral fractures, low bone mineral density and concurrent bone density loss, low body weight, and concurrent weight loss. Thus, age-related kyphosis progression may be best prevented by slowing bone density loss and avoiding weight loss. PMID:22865329

  5. High frame-rate real-time x-ray imaging of in situ high-velocity rifle bullets

    NASA Astrophysics Data System (ADS)

    D'Aries, Lawrence J.; Miller, Stuart R.; Robertson, Rob; Singh, Bipin; Nagarkar, Vivek V.

    2016-05-01

    High frame-rate imaging is a valuable tool for non-destructive evaluation (NDE) as well as for ballistic impact studies (terminal ballistics), in-flight projectile imaging, studies of exploding ordnance and characterization of other high-speed phenomena. Current imaging systems exist for these studies, however, none have the ability to do in-barrel characterization (in-bore ballistics) to image kinetics of the moving projectile BEFORE it exits the barrel. The system uses an intensified high-speed CMOS camera coupled to a specially designed scintillator to serve as the X-ray detector. The X-ray source is a sequentially fired portable pulsed unit synchronized with the detector integration window and is able to acquire 3,600 frames per second (fps) with mega-pixel spatial resolution and up to 500,000 fps with reduced pixel resolution. This paper will discuss our results imaging .30 caliber bullets traveling at ~1,000 m/s while still in the barrel. Information on bullet deformation, pitch, yaw and integrity are the main goals of this experimentation. Planned future upgrades for imaging large caliber projectiles will also be discussed.

  6. Marine mammal strandings and environmental changes: a 15-year study in the St. Lawrence ecosystem.

    PubMed

    Truchon, Marie-Hélène; Measures, Lena; L'Hérault, Vincent; Brêthes, Jean-Claude; Galbraith, Peter S; Harvey, Michel; Lessard, Sylvie; Starr, Michel; Lecomte, Nicolas

    2013-01-01

    Understanding the effects of climatic variability on marine mammals is challenging due to the complexity of ecological interactions. We used general linear models to analyze a 15-year database documenting marine mammal strandings (1994-2008; n = 1,193) and nine environmental parameters known to affect marine mammal survival, from regional (sea ice) to continental scales (North Atlantic Oscillation, NAO). Stranding events were more frequent during summer and fall than other seasons, and have increased since 1994. Poor ice conditions observed during the same period may have affected marine mammals either directly, by modulating the availability of habitat for feeding and breeding activities, or indirectly, through changes in water conditions and marine productivity (krill abundance). For most species (75%, n = 6 species), a low volume of ice was correlated with increasing frequency of stranding events (e.g. R(2)adj = 0.59, hooded seal, Cystophora cristata). This likely led to an increase in seal mortality during the breeding period, but also to increase habitat availability for seasonal migratory cetaceans using ice-free areas during winter. We also detected a high frequency of stranding events for mysticete species (minke whale, Balaenoptera acutorostrata) and resident species (beluga, Delphinapterus leucas), correlated with low krill abundance since 1994. Positive NAO indices were positively correlated with high frequencies of stranding events for resident and seasonal migratory cetaceans, as well as rare species (R(2)adj = 0.53, 0.81 and 0.34, respectively). This contrasts with seal mass stranding numbers, which were negatively correlated with a positive NAO index. In addition, an unusual multiple species mortality event (n = 114, 62% of total annual mortality) in 2008 was caused by a harmful algal bloom. Our findings provide an empirical baseline in understanding marine mammal survival when faced with climatic variability. This is a promising

  7. The Bender Gestalt test for 5- to 15-year old Brazilian children: norms and validity.

    PubMed

    Brito, G N; Santos, T R

    1996-11-01

    Norms for two modalities (normal and stress) of the Bender Gestalt test were developed for the neuropsychological assessment of children in the greater Rio de Janeiro area. For each modality, a measure of performance, a measure of speed and a measure of emotional disturbance were obtained. A total of 398 children (199 males and 199 females), 5 to 15 years old, who were attending a public school in Niterói were the subjects of this study. Analysis of the data revealed that age, but not sex, had a significant effect on performance, but not on speed, in both modalities such that older children made fewer errors than younger children. Also, the number of emotional indicators significantly decreased with age. Additionally, boys needed more time to complete the normal modality than girls, and showed a higher number of emotional indicators in both modalities. The Bender test was found to be valid in the sense that children who had failed at least one grade in school performed worse than those who had not. The number of emotional indicators was shown to be valid since it was significantly correlated with factors such as hyperactivity-conduct problem, and independent functioning, and inattention of the Composite Teacher Rating Scale (Brito GNO and Pinto RCA (1991). Journal of Clinical and Experimental Neuropsychology, 13: 417-418). We conclude that the Bender test is valid for use in schoolchildren, and the number of emotional indicators is valid as an index of psychopathology, but sex and age should be considered when using the norms in Brazil.

  8. Hearing and loud music exposure in 14-15 years old adolescents.

    PubMed

    Serra, Mario R; Biassoni, Ester C; Hinalaf, María; Abraham, Mónica; Pavlik, Marta; Villalobo, Jorge Pérez; Curet, Carlos; Joekes, Silvia; Yacci, María R; Righetti, Andrea

    2014-01-01

    Adolescent exposure to loud music has become a social and health problem whose study demands a holistic approach. The aims of the current study are: (1) To detect early noise-induced hearing loss among adolescents and establish its relationship with their participation in musical recreational activities and (2) to determine sound immission levels in nightclubs and personal music players (PMPs). The participants consisted in 172 14-15 years old adolescents from a technical high school. Conventional and extended high frequency audiometry, transient evoked otoacoustic emissions and questionnaire on recreational habits were administered. Hearing threshold levels (HTLs) were classified as: normal (Group 1), slightly shifted (Group 2), and significantly shifted (Group 3). The musical general exposure (MGE), from participation in recreational musical activities, was categorized in low, moderate, and high exposure. The results revealed an increase of HTL in Group 2 compared with Group 1 (P < 0.01), in Group 3 compared with Group 2 (P < 0.05) only in extended high frequency range, in Group 3 compared with Group 1 (P < 0.01). Besides, a decrease in mean global amplitude, reproducibility and in frequencies amplitude in Group 2 compared with Group 1 (P < 0.05) and in Group 3 compared with Group 1 (P < 0.05). A significant difference (P < 0.05) was found in Group 1's HTL between low and high exposure, showing higher HTL in high exposure. The sound immission measured in nightclubs (107.8-112.2) dBA and PMPs (82.9-104.6) dBA revealed sound levels risky for hearing health according to exposure times. It demonstrates the need to implement preventive and hearing health promoting actions in adolescents.

  9. Obstructive Sleep Apnea and 15-Year Cognitive Decline: The Atherosclerosis Risk in Communities (ARIC) Study

    PubMed Central

    Lutsey, Pamela L.; Bengtson, Lindsay G.S.; Punjabi, Naresh M.; Shahar, Eyal; Mosley, Thomas H.; Gottesman, Rebecca F.; Wruck, Lisa M.; MacLehose, Richard F.; Alonso, Alvaro

    2016-01-01

    Study Objectives: Prospective data evaluating abnormal sleep quality and quantity with cognitive decline are limited because most studies used subjective data and/or had short follow-up. We hypothesized that, over 15 y of follow-up, participants with objectively measured obstructive sleep apnea (OSA) and other indices of poor sleep quantity and quality would experience greater decline in cognitive functioning than participants with normal sleep patterns. Methods: ARIC participants (n = 966; mean age 61 y, 55% women) with in-home polysomnography (1996–1998) and repeated cognitive testing were followed for 15 y. Three cognitive tests (Delayed Word Recall, Word Fluency, and Digit Symbol Substitution) were administered at two time points (1996–1998 and 2011–2013). Ten additional cognitive tests were administered at the 2011–2013 neurocognitive examination. OSA was modeled using established clinical OSA severity categories. Multivariable linear regression was used to explore associations of OSA and other sleep indices with change in cognitive tests between the two assessments. Results: A median of 14.9 y (max: 17.3) passed between the two cognitive assessments. OSA category and additional indices of sleep (other measures of hypoxemia and disordered breathing, sleep fragmentation, sleep duration) were not associated with change in any cognitive test. Analyses of OSA severity categories and 10 cognitive tests administered only in 2011–2013 also showed little evidence of an association. Conclusions: Overall, abnormal sleep quality and quantity at midlife was not related to cognitive decline and later-life cognition. The effect of adverse sleep quality and quantity on cognitive decline among the elderly remains to be determined. Citation: Lutsey PL, Bengtson LG, Punjabi NM, Shahar E, Mosley TH, Gottesman RF, Wruck LM, MacLehose RF, Alonso A. Obstructive sleep apnea and 15-year cognitive decline: the Atherosclerosis Risk in Communities (ARIC) study. SLEEP 2016

  10. Citation Analysis of the Croatian Medical Journal: the First 15 Years

    PubMed Central

    Kovačić, Nataša; Huić, Mirjana; Ivaniš, Ana

    2008-01-01

    The Croatian Medical Journal (CMJ) is a bimonthly scientific journal, publishing mostly original articles. It is indexed in the Index Medicus/MEDLINE, Current Contents/Clinical Medicine, and the Science Citation Index – expanded. Since the CMJ’s 15th anniversary in 2007, our aim has been to assess the importance of the journal through its impact factor (IF) and immediacy index, with a particular focus placed on the proportion of self-citations. According the Web of Knowledge database, the current official IF for CMJ is 0.825, ranking it at the 62nd place out of 103 journals within the Thomson Scientific category “Medicine – General and Internal.” The exclusion of self-citations resulted in a small decrease in the journal’s rank – to 66th place. According to the Web of Science database, the predicted CMJ IF in 2007 is between 1.024 and 1.125, showing a clear increase. The immediacy index of the CMJ is continuously low, with a high contribution of self-citations, implying that articles published in the CMJ require more time to be cited, and that their topics are of particular interest to the journal's readers and contributors. Self-citations contributed significantly to the IF in the first few years after the journal was established. The proportion of independent citations progressively increased, and of all the citations included in the IF in 2007, almost 70% were fully independent. Some of these citations were from articles published in journals with IF higher than 5. Taken together, our data suggest that CMJ has significantly improved its citation data during the last 15 years, confirming that a quality-oriented editorial policy in a small peripheral journal may result in a truly increased international visibility. PMID:18293451

  11. Hearing and loud music exposure in 14-15 years old adolescents.

    PubMed

    Serra, Mario R; Biassoni, Ester C; Hinalaf, María; Abraham, Mónica; Pavlik, Marta; Villalobo, Jorge Pérez; Curet, Carlos; Joekes, Silvia; Yacci, María R; Righetti, Andrea

    2014-01-01

    Adolescent exposure to loud music has become a social and health problem whose study demands a holistic approach. The aims of the current study are: (1) To detect early noise-induced hearing loss among adolescents and establish its relationship with their participation in musical recreational activities and (2) to determine sound immission levels in nightclubs and personal music players (PMPs). The participants consisted in 172 14-15 years old adolescents from a technical high school. Conventional and extended high frequency audiometry, transient evoked otoacoustic emissions and questionnaire on recreational habits were administered. Hearing threshold levels (HTLs) were classified as: normal (Group 1), slightly shifted (Group 2), and significantly shifted (Group 3). The musical general exposure (MGE), from participation in recreational musical activities, was categorized in low, moderate, and high exposure. The results revealed an increase of HTL in Group 2 compared with Group 1 (P < 0.01), in Group 3 compared with Group 2 (P < 0.05) only in extended high frequency range, in Group 3 compared with Group 1 (P < 0.01). Besides, a decrease in mean global amplitude, reproducibility and in frequencies amplitude in Group 2 compared with Group 1 (P < 0.05) and in Group 3 compared with Group 1 (P < 0.05). A significant difference (P < 0.05) was found in Group 1's HTL between low and high exposure, showing higher HTL in high exposure. The sound immission measured in nightclubs (107.8-112.2) dBA and PMPs (82.9-104.6) dBA revealed sound levels risky for hearing health according to exposure times. It demonstrates the need to implement preventive and hearing health promoting actions in adolescents. PMID:25209042

  12. Behavioural early-life exposures and body composition at age 15 years

    PubMed Central

    Leary, S D; Lawlor, D A; Davey Smith, G; Brion, M J; Ness, A R

    2015-01-01

    Background/Objectives: Previous studies have demonstrated associations between some early-life exposures and later obesity, but most have used body mass index in childhood or adulthood as the outcome. The objective of this study was to investigate whether early-life exposures were associated with directly measured fat and lean mass in adolescence. Subjects/Methods: This study used data on 4750 mother–offspring pairs, collected as a part of the Avon Longitudinal Study of Parents and Children, Bristol, UK between 1991 and 1992; associations between behavioural exposures occurring from conception up to 5 years of age (maternal and paternal smoking during pregnancy, breastfeeding, age at introduction to solids, dietary patterns and physical inactivity during early childhood) and offspring body composition measured by dual-energy X-ray absorptiometry at ~15 years were assessed. Results: After full adjustment for potential confounders, maternal smoking during pregnancy, having a junk food diet and spending more time watching television in early childhood were all associated with higher fat mass at age 15, whereas maternal smoking, having a healthy diet and playing computer games more frequently in early childhood were all associated with a higher lean mass at age 15. Associations with paternal smoking were generally weaker for both fat and lean mass, but as there was no strong statistical evidence for maternal vs paternal differences, confounding by social factors rather than a direct effect of maternal smoking cannot be ruled out. Early feeding was not associated with fat or lean mass at age 15. Conclusions: This study does not provide compelling evidence for associations between most early-life factors and body composition in adolescence. However, possible associations with dietary patterns and physical inactivity in early childhood require further investigation in other cohorts that have direct measurements of adolescent body composition. PMID:25664839

  13. Population Based National Tuberculosis Prevalence Survey among Adults (>15 Years) in Pakistan, 2010–2011

    PubMed Central

    Qadeer, Ejaz; Fatima, Razia; Yaqoob, Aashifa; Tahseen, Sabira; Ul Haq, Mahboob; Ghafoor, Abdul; Asif, Muhammad; Straetemans, Masja; Tiemersma, Edine W.

    2016-01-01

    Background We aimed to determine the prevalence of pulmonary tuberculosis (TB) amongst the adult population in 2010–2011 in Pakistan. Method A nationwide cross-sectional survey with multistage cluster sampling was conducted among adults (≥15 years) in 95 clusters in 2010–2011. All consenting participants were screened for cough and by chest X-ray. Participants with presumptive TB submitted two sputum samples for smear microscopy, culture, and molecular testing if needed. The TB prevalence estimates were adjusted for missing data and the cluster design. Result Of 131,329 eligible individuals, 105,913 (81%) participated in the survey, of whom 10,471 (9.9%) were eligible for sputum examination. We found 341 bacteriologically positive TB cases of whom 233 had sputum smear-positive TB. The adjusted prevalence estimates for smear and bacteriologically positive TB were 270/100,000 (95% confidence interval (CI) 217–323), and 398/100,000 (95% CI 333–463), respectively. Only 61% of the diagnosed TB cases screened positive on symptoms (cough >2wks), whereas the other TB cases were detected based on X-ray abnormalities. The TB prevalence increased with age and was 1.8 times higher among men than women. The prevalence-to-notification ratio of smear-positive TB was 3.1 (95% CI 2.5–3.7), was higher among men than women, and increased with age. Conclusion Our data suggest that there is under-detection and/or -notification of TB, especially among men and elderly. TB control should be strengthened specifically in these risk groups. X-ray examination should be combined with symptom screening to enhance case detection. PMID:26863617

  14. Citation analysis of the Croatian Medical Journal: the first 15 years.

    PubMed

    Kovacić, Natasa; Huić, Mirjana; Ivanis, Ana

    2008-02-01

    The Croatian Medical Journal (CMJ) is a bimonthly scientific journal, that publishes mostly original articles. It is indexed in the Index Medicus/MEDLINE, Current Contents/Clinical Medicine, and the Science Citation Index Expanded. Since the CMJ's 15th anniversary in 2007, our aim has been to assess the importance of the Journal through its impact factor (IF) and immediacy index, with a particular focus placed on the proportion of self-citations. According the Web of Knowledge database, the current official IF for the CMJ is 0.825, ranking it 62nd out of 103 journals within the Thomson Scientific category "Medicine - General and Internal." The exclusion of self-citations resulted in a small decrease in the journal's rank - to 66th place. According to the Web of Science database, the predicted CMJ IF in 2007 is between 1.024 and 1.125, showing a clear increase. The immediacy index of the CMJ is continuously low, with a high contribution of self-citations, implying that articles published in the CMJ require more time to be cited, and that their topics are of particular interest to the journal's readers and contributors. Self-citations contributed significantly to the IF in the first few years after the journal was established. The proportion of independent citations progressively increased, and of all the citations included in the IF in 2007, almost 70% were fully independent. Some of these citations were from articles published in journals with IF higher than 5. Taken together, our data suggest that the CMJ has significantly improved its citation ratings during the last 15 years, confirming that a quality-oriented editorial policy in a small peripheral journal may result in a truly increased international visibility.

  15. Multi-Directional Sprinting and Acceleration Phase in Basketball and Handball Players Aged 14 and 15 Years.

    PubMed

    Popowczak, Marek; Rokita, Andrzej; Struzik, Artur; Cichy, Ireneusz; Dudkowski, Andrzej; Chmura, Paweł

    2016-10-01

    An important role in handball and basketball is played by ability to accelerate and ability to repeat multiple sprints. The aim of the study was to assess level of ability in multi-directional sprinting and running time over the first 5 m of the 30 m sprint in 93 basketball and handball players (46 boys and 47 girls) aged 14 to 15 years. The attempts were also made to find the relationships between the time of a 5-m run to evaluate initial acceleration phase and multi-directional sprinting evaluated using Five-Time Shuttle Run To Gates Test Statistical analysis revealed no important differences in times of 5-m runs and times of multi-directional sprinting between groups with different ages, genders, and sports specialties. Furthermore, no significant correlations were found based on Spearman's rank correlation coefficient between times of 5-m run and multi-directional sprinting in the most of subgroups studied.

  16. Placement from a Community-Based Mental Retardation Program: A 15-Year Follow-Up.

    ERIC Educational Resources Information Center

    Schalock, Robert L.; Genung, Tom L.

    1993-01-01

    Eighty-five persons with developmental disabilities who had been placed into independent housing and competitive employment 15 years previously were evaluated. Two primary groups emerged: 19% in and 59% not in mental retardation/developmental disability services. The two groups were compared on social and support networks, lifestyle, quality of…

  17. Mathematical Literacy of Hong Kong's 15-Year-Old Students in PISA

    ERIC Educational Resources Information Center

    Wong, Ka-Ming Patrick

    2003-01-01

    This article reports the performance of 15-year-old Hong Kong students in mathematical literacy in an international study called PISA 2000, in which Hong Kong has topped the list of 41 participating countries/regions, with a mean score significantly higher than all other countries except Japan and Korea. With the conceptual framework developed by…

  18. Children Treated for Nocturnal Enuresis: Characteristics and Trends over a 15-Year Period

    ERIC Educational Resources Information Center

    Kushnir, Jonathan; Kushnir, Baruch; Sadeh, Avi

    2013-01-01

    Background: Nocturnal Enuresis (NE) is one of the most prevalent childhood disorders and has significant negative psychosocial impact on the child and family. Objective: To assess the characteristics of children with NE and trends over a 15-year period. Methods: The study included 18,677 children [11,205 (60%) boys and 7,472 (40%) girls] referred…

  19. Stability and Change in Counseling Psychologists' Identities, Roles, Functions, and Career Satisfaction across 15 Years

    ERIC Educational Resources Information Center

    Goodyear, Rodney K.; Murdock, Nancy; Lichtenberg, James W.; McPherson, Robert; Koetting, Kristin; Petren, Suzanne

    2008-01-01

    The authors examined changes in the profession of counseling psychology by comparing results of similar surveys of Society of Counseling Psychology (SCP) members administered 15 years apart (in 1985 and 2000). The authors found the roles and settings of SCP members were relatively stable across this period but observed that notably fewer…

  20. Five Years of Tamoxifen Continues to Benefit Women 15 Years after Treatment

    Cancer.gov

    In a large randomized clinical trial, women with early-stage breast cancer who received 5 years of adjuvant treatment with tamoxifen had better outcomes up to 15 years after the start of treatment than those who received 2 years of tamoxifen therapy.

  1. PUBIS STRESS FRACTURE IN A 15-YEAR-OLD SOCCER PLAYER

    PubMed Central

    Bertolini, Fabrício Melo; Vieira, Rodrigo Barreiros; Oliveira, Lucas Henrique Araujo de; Lasmar, Rodrigo Pace; Junior, Otaviano de Oliveira

    2015-01-01

    This case report presents a 15-year-old football player who was diagnosed with a pubis stress fracture and underwent conservative treatment with satisfactory results. After a review of the literature, the clinical picture, diagnosis and treatment are described. The importance of this paper comes from the rarity of finding reports about this kind of injury in the literature. PMID:27027039

  2. Psychosocial Precursors and Correlates of Differing Internalizing Trajectories from 3 to 15 Years

    ERIC Educational Resources Information Center

    Letcher, Primrose; Smart, Diana; Sanson, Ann; Toumbourou, John W.

    2009-01-01

    Psychosocial precursors and correlates of parent-reported internalizing behavior trajectories across the age span of 3-15 years were explored using a community-based cohort of Australian children. Six internalizing trajectories had previously been identified for both girls (N = 810) and boys (N = 874) in this sample, comprising stable low, high,…

  3. Observations about Research Methodology during 15 Years of Presenting Capacity-Building Seminars

    ERIC Educational Resources Information Center

    van der Walt, Johannes L.

    2016-01-01

    In this paper, the author shares some of his most important impressions and experiences that he accumulated over a span of more than 15 years of facilitating courses in the foundations of scholarship and article-writing. This is done in an effort to stimulate discussion about the "art" of article-writing and also to help budding academic…

  4. How "Green" Are Today's 15-Year-Olds? PISA in Focus. No. 15

    ERIC Educational Resources Information Center

    OECD Publishing (NJ1), 2012

    2012-01-01

    How "green" are 15-year-olds? To what extent do they understand environmental issues? What are the sources of their information about the environment? Can they apply scientific principles and evidence to the world around them? This paper reports that across OECD (Organisation for Economic Cooperation and Development) countries, around one in five…

  5. Development of Face Recognition in 5- to 15-Year-Olds

    ERIC Educational Resources Information Center

    Kinnunen, Suna; Korkman, Marit; Laasonen, Marja; Lahti-Nuuttila, Pekka

    2013-01-01

    This study focuses on the development of face recognition in typically developing preschool- and school-aged children (aged 5 to 15 years old, "n" = 611, 336 girls). Social predictors include sex differences and own-sex bias. At younger ages, the development of face recognition was rapid and became more gradual as the age increased up…

  6. The Asset-Burden Paradox of Giftedness: A 15-Year Phenomenological, Longitudinal Case Study

    ERIC Educational Resources Information Center

    Peterson, Jean Sunde

    2012-01-01

    A 15-year phenomenological case study of an exceptional female from age 15 through 30 was focused on exploring the subjective experience of development during adolescence and young adulthood, with attention to how giftedness and context interacted. The main focus became her response to trauma, which was revealed early in the study. Data, including…

  7. Characteristics of 15-Year-Old Students Predicting Scientific Literacy Skills in Turkey

    ERIC Educational Resources Information Center

    Demir, Ergül

    2016-01-01

    Since 2003, Turkey regularly participates in PISA. According to the PISA 2012 results, 15-year-old students in Turkey performed below both OECD countries and participating countries. Defining the relations between students' characteristics and their scientific literacy skills is thought to provide deeper understanding for the nature of this…

  8. Squamous cell carcinoma of esophagus in a 15-year-old boy

    PubMed Central

    Hedawoo, J. B.; Nagdeve, N. G.; Sarve, G. N.

    2010-01-01

    A 15-year-old boy with well-differentiated squamous cell carcinoma of the lower esophagus is reported because of its rarity. The patient presented with dysphagia for 3 months and weight loss. The case was treated with radical excision, with excellent immediate response. PMID:20975784

  9. The Relationship between Bible Reading and Attitude toward Substance Use among 13-15 Year Olds

    ERIC Educational Resources Information Center

    Francis, Leslie J.

    2002-01-01

    The relationship between Bible reading and attitude toward drug use is examined among a sample of 25,888 teenagers, 13-15 year olds, throughout England and Wales. Information about sex, age, personality, belief in God, and church attendance was also considered. The conclusion is that Bible reading makes a small but significant contribution to…

  10. Behavior Disorders and Learning Disabilities over 15 Years in Rural Vermont.

    ERIC Educational Resources Information Center

    Huessy, Hans R.

    Early identification of Minimal Brain Dysfunction (MBD) is now easier, partly as a result of a series of 3 studies made in rural Vermont over a period of 15 years. MBD victims exhibit different behaviors at different ages. "Fidgetiness", a "nuisance" factor, and poor learning are all strong predictors of MBD for children at the 9th grade level.…

  11. Identifying Issue Frames in Text

    PubMed Central

    Sagi, Eyal; Diermeier, Daniel; Kaufmann, Stefan

    2013-01-01

    Framing, the effect of context on cognitive processes, is a prominent topic of research in psychology and public opinion research. Research on framing has traditionally relied on controlled experiments and manually annotated document collections. In this paper we present a method that allows for quantifying the relative strengths of competing linguistic frames based on corpus analysis. This method requires little human intervention and can therefore be efficiently applied to large bodies of text. We demonstrate its effectiveness by tracking changes in the framing of terror over time and comparing the framing of abortion by Democrats and Republicans in the U.S. PMID:23874909

  12. ALH84001: The Key to Unlocking Secrets About Mars-15 Years and Counting

    NASA Technical Reports Server (NTRS)

    Gibson, Everett K.

    2011-01-01

    From the December 27, 1984 discovery of ALH84001, and its subsequent identification as a sample of Mars in 1993, mystery and debate has surrounded the meteorite. With the realization that the ALH84001 sample was a orthopyroxenite and one of the oldest SNC meteorites (4.09 Ga) available to study, important and critical information about the Martian hydrosphere and atmosphere along with the early history and evolution of the planet could be obtained by studying the unique carbonate globules (3.9 Ga) in the sample. The initial work showed the carbonate globules were deposited within fractures and cracks in the host-orthopyroxene by low-temperature aqueous fluids. Ideas that the carbonates were formed at temperatures approaching 800oC were ruled out by later experiments. The 1996 announcement by McKay et al. that ALH84001 contained features which could be interpreted as having a biogenic origin generated considerable excitement and criticism. The NASA Administrator Dan Golden said the 1996 ALH84001 announcement saved NASA s Mars planetary exploration program and injected $6 billion dollars over five years into the scientific research and analysis efforts. All of the original four lines of evidence for possible biogenic features within ALH84001 offered by McKay et al. have withstood the test of time. Criticism has been directed at the interpretation of the 1996 analytical data. Research has expanded to other SNC meteorites. Despite the numerous attacks on the ideas, the debate continues after 15 years. The 2009 paper by Thomas-Keprta et al. on the origins of a suite of magnetites within the ALH84001 has offered strong arguments that some of the magnetites can only be formed by biogenic processes and not from thermal decomposition or shock events which happened to the meteorite. NASA s Astrobiology Institute was formed from the foundation laid by the ALH84001 hypothesis of finding life beyond the Earth. The strong astrobiology outreach programs have expanded because of

  13. 29 CFR 570.34 - Occupations that may be performed by minors 14 and 15 years of age.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Occupations that may be performed by minors 14 and 15 years... performed by minors 14 and 15 years of age. This subpart authorizes only the following occupations in which the employment of minors 14 and 15 years of age is permitted when performed for periods and...

  14. 29 CFR 570.33 - Occupations that are prohibited to minors 14 and 15 years of age.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Occupations that are prohibited to minors 14 and 15 years... prohibited to minors 14 and 15 years of age. The following occupations, which is not an exhaustive list... who are 14 and 15 years of age: (a) Manufacturing, mining, or processing occupations,...

  15. 29 CFR 570.31 - Secretary's determinations concerning the employment of minors 14 and 15 years of age.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... minors 14 and 15 years of age. 570.31 Section 570.31 Labor Regulations Relating to Labor (Continued) WAGE... determinations concerning the employment of minors 14 and 15 years of age. Link to an amendment published at 75... concerning the employment of minors 14 and 15 years of age. The employment of minors between 14 and 16...

  16. 29 CFR 570.33 - Occupations that are prohibited to minors 14 and 15 years of age.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Occupations that are prohibited to minors 14 and 15 years... prohibited to minors 14 and 15 years of age. The following occupations, which is not an exhaustive list... who are 14 and 15 years of age: (a) Manufacturing, mining, or processing occupations,...

  17. 29 CFR 570.33 - Occupations that are prohibited to minors 14 and 15 years of age.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Occupations that are prohibited to minors 14 and 15 years... prohibited to minors 14 and 15 years of age. The following occupations, which is not an exhaustive list... who are 14 and 15 years of age: (a) Manufacturing, mining, or processing occupations,...

  18. 29 CFR 570.33 - Occupations that are prohibited to minors 14 and 15 years of age.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Occupations that are prohibited to minors 14 and 15 years... prohibited to minors 14 and 15 years of age. The following occupations, which is not an exhaustive list... who are 14 and 15 years of age: (a) Manufacturing, mining, or processing occupations,...

  19. Consumption of dairy products and the 15-year incidence of age-related macular degeneration.

    PubMed

    Gopinath, Bamini; Flood, Victoria M; Louie, Jimmy C Y; Wang, Jie Jin; Burlutsky, George; Rochtchina, Elena; Mitchell, Paul

    2014-05-01

    Habitual consumption of dairy products has been shown to play an important role in the prevention of several chronic diseases. We aimed to prospectively assess the relationship between the change in dairy product consumption (both regular fat and low/reduced fat) and the 15-year incidence of age-related macular degeneration (AMD). In the Blue Mountains Eye Study, 2037 participants aged 49 years or above at baseline were re-examined at follow-up in 1997-9, 2002-4 and/or 2007-9. AMD was assessed from retinal photographs. Dietary data were collected using a semi-quantitative FFQ, and servings of dairy product consumption calculated. Over the 15-year follow-up, there were 352, 268 and eighty-four incident cases of any, early and late AMD, respectively. After adjusting for age, sex, current smoking, white cell count and fish consumption, a significant linear trend (P for trend = 0·003) was observed with decreasing consumption of total dairy foods and the 15-year incidence of late AMD, comparing the lowest v. highest quintile of intake (OR 2·80, 95 % CI 1·21, 3·04). Over the 15 years, decreased consumption of reduced-fat dairy foods was associated with an increased risk of incident late AMD, comparing the lowest to highest quintile of intake (OR 3·10, 95 % CI 1·18, 8·14, P for trend = 0·04). Decreasing total dietary Ca intake over the 15 years was also associated with an increased risk of developing incident late AMD (multivariable-adjusted P for trend = 0·03). A lower consumption of dairy products (regular and low fat) and Ca was independently associated with a higher risk of developing incident late AMD in the long term. Additional cohort studies are needed to confirm these findings.

  20. The outcome at 15 years of endoscopic anterior cruciate ligament reconstruction using hamstring tendon autograft for 'isolated' anterior cruciate ligament rupture.

    PubMed

    Bourke, H E; Gordon, D J; Salmon, L J; Waller, A; Linklater, J; Pinczewski, L A

    2012-05-01

    The purpose of this study was to report the outcome of 'isolated' anterior cruciate ligament (ACL) ruptures treated with anatomical endoscopic reconstruction using hamstring tendon autograft at a mean of 15 years (14.25 to 16.9). A total of 100 consecutive men and 100 consecutive women with 'isolated' ACL rupture underwent four-strand hamstring tendon reconstruction with anteromedial portal femoral tunnel drilling and interference screw fixation by a single surgeon. Details were recorded pre-operatively and at one, two, seven and 15 years post-operatively. Outcomes included clinical examination, subjective and objective scoring systems, and radiological assessment. At 15 years only eight of 118 patients (7%) had moderate or severe osteo-arthritic changes (International Knee Documentation Committee Grades C and D), and 79 of 152 patients (52%) still performed very strenuous activities. Overall graft survival at 15 years was 83% (1.1% failure per year). Patients aged < 18 years at the time of surgery and patients with > 2 mm of laxity at one year had a threefold increase in the risk of suffering a rupture of the graft (p = 0.002 and p = 0.001, respectively). There was no increase in laxity of the graft over time. ACL reconstructive surgery in patients with an 'isolated' rupture using this technique shows good results 15 years post-operatively with respect to ligamentous stability, objective and subjective outcomes, and does not appear to cause osteoarthritis.

  1. Rotary Blood Pumps as Long-Term Mechanical Circulatory Support: A Review of a 15-Year Berlin Experience.

    PubMed

    Hetzer, Roland; Kaufmann MEng, Friedrich; Potapov, Evgenij; Krabatsch, Thomas; Delmo Walter, Eva Maria

    2016-01-01

    This article reports our 15-year single-center experience with rotary blood pumps (RBPs) as long-term mechanical circulatory support (MCS) with emphasis on outcomes. For more than 15-year period, we have used various RBPs as bridge to transplantation or to myocardial recovery. Our group performed the first human implantation worldwide of RBCs, the MicroMed DeBakey ventricular assist device in November 1998 in a patient with end-stage heart failure who was supported for 47 days until his death. Based on this initial experience, we recognized the feasibility of providing long-term support and since then it has been our primary armamentarium in treating patients with heart failure. Between 1987 and September 2013, we have implanted 2208 ventricular assist devices ranging from pulsatile to continuous-flow systems, as short-term, long-term, or permanent support in patients with end-stage heart failure. In total, 1009 RBPs were implanted on 908 patients, and their outcomes are reported here. We have shared some milestones in MCS including the first implantation of Jarvik 2000 on the oldest patient (81-year old) in 2008 and the first worldwide implantation of a biventricular HeartWare. Over time, implantation techniques, anticoagulation, and postoperative care have been modified and individualized. A relevant aspect of our experience has been the incidence of pump thrombosis. This is particularly frustrating because the problem has occurred in the setting of full anticoagulation and antiplatelet therapy, guided by strict anticoagulation monitoring. It has become clear to us that the devices are still not perfect. Technical pump failures such as cable breaks also occur, prompting urgent pump exchange, and infection. A 15-year cumulative mortality rate is 46.9%. This report emphasizes that MCS with RBPs has evolved into a routine treatment in heart failure and is a highly feasible option for permanent therapy particularly for elderly patients. PMID:27568128

  2. Rotary Blood Pumps as Long-Term Mechanical Circulatory Support: A Review of a 15-Year Berlin Experience.

    PubMed

    Hetzer, Roland; Kaufmann MEng, Friedrich; Potapov, Evgenij; Krabatsch, Thomas; Delmo Walter, Eva Maria

    2016-01-01

    This article reports our 15-year single-center experience with rotary blood pumps (RBPs) as long-term mechanical circulatory support (MCS) with emphasis on outcomes. For more than 15-year period, we have used various RBPs as bridge to transplantation or to myocardial recovery. Our group performed the first human implantation worldwide of RBCs, the MicroMed DeBakey ventricular assist device in November 1998 in a patient with end-stage heart failure who was supported for 47 days until his death. Based on this initial experience, we recognized the feasibility of providing long-term support and since then it has been our primary armamentarium in treating patients with heart failure. Between 1987 and September 2013, we have implanted 2208 ventricular assist devices ranging from pulsatile to continuous-flow systems, as short-term, long-term, or permanent support in patients with end-stage heart failure. In total, 1009 RBPs were implanted on 908 patients, and their outcomes are reported here. We have shared some milestones in MCS including the first implantation of Jarvik 2000 on the oldest patient (81-year old) in 2008 and the first worldwide implantation of a biventricular HeartWare. Over time, implantation techniques, anticoagulation, and postoperative care have been modified and individualized. A relevant aspect of our experience has been the incidence of pump thrombosis. This is particularly frustrating because the problem has occurred in the setting of full anticoagulation and antiplatelet therapy, guided by strict anticoagulation monitoring. It has become clear to us that the devices are still not perfect. Technical pump failures such as cable breaks also occur, prompting urgent pump exchange, and infection. A 15-year cumulative mortality rate is 46.9%. This report emphasizes that MCS with RBPs has evolved into a routine treatment in heart failure and is a highly feasible option for permanent therapy particularly for elderly patients.

  3. Physical activity, fitness and body composition of Finnish police officers: a 15-year follow-up study.

    PubMed

    Sörensen, L; Smolander, J; Louhevaara, V; Korhonen, O; Oja, P

    2000-01-01

    This study evaluated changes in the physical activity, fitness and body composition of 103 police officers during a 15-year follow-up. The absolute aerobic capacity was similar in 1981 and 1996, muscular performance had declined, and body weight had increased approximately 0.5 kg/year. More than half the subjects (53%) had increased their leisure-time physical activity in 1996. The correlation was significant between physical activity in 1981 and physical fitness in 1996, but weak between physical activity in 1996 and fitness in 1996. It was also significant between waist circumference and waist/hip ratio in 1996 and physical activity during the previous 5 and 15 years. No significant correlations were found between physical activity and work ability or perceived physical or mental job stress. The physical fitness of middle-aged police officers seems to be predicted strongly by physical activity in early adulthood. Therefore health and fitness promotion measures should start at that time. This, together with regular systematic training, should help to sustain work ability of middle-aged police officers.

  4. Trisomy 18 mosaicism in a 15-year-old boy with normal intelligence and short stature

    SciTech Connect

    1995-05-08

    We report a 15-year-old boy with mosaicism for trisomy 18 and normal intelligence. Approximately 50% of his leukocytes are trisomic. This patient represents the sixth report of an individual with trisomy 18 mosaicism and normal intelligence. Those individuals with trisomy 18 mosaicism and normal intelligence need to be advised of increased risks for offspring with chromosome abnormalities and offered the option of prenatal diagnosis for cytogenetic anomalies. 6 refs.

  5. Type IV congenital laryngeal web: Case report and 15 year follow up.

    PubMed

    Sorichetti, Brendan; Moxham, John P; Kozak, Frederick K

    2016-01-01

    A five day old patient with mild VACTERL syndrome had repair of a type IV congenital laryngeal web with successful decannulation 76 days later. Voice and respiratory outcome is good with follow up 15 years later. This case presents a rare clinical finding of a type IV laryngeal web successfully repaired with a keel and subsequent long term follow up during an era when it was suggested that repair be delayed until 18 months of age at the earliest. PMID:26954872

  6. Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update

    PubMed Central

    Mishra, Kavita K.; Squire, Sarah; Lamborn, Kathleen; Banerjee, Anuradha; Gupta, Nalin; Wara, William M.; Prados, Michael D.; Berger, Mitchel S.

    2010-01-01

    To report long-term results for children with low-grade hypothalamic/chiasmatic gliomas treated on a phase II chemotherapy protocol. Between 1984 and 1992, 33 children with hypothalamic/chiasmatic LGGs received TPDCV chemotherapy on a phase II prospective trial. Median age was 3.0 years (range 0.3–16.2). Twelve patients (36%) underwent STRs, 14 (42%) biopsy only, and seven (21%) no surgery. Twenty patients (61%) had pathologic JPAs, nine (27%) grade II gliomas, and four (12%) no surgical sampling. Median f/u for surviving patients was 15.2 years (range 5.3–20.7); 20 of the 23 surviving patients had 14 or more years of follow-up. Fifteen-year PFS and OS were 23.4 and 71.2%, respectively. Twenty-five patients progressed, of whom 13 are NED, two are AWD, and 10 have died. All children who died were diagnosed and first treated at age three or younger. Age at diagnosis was significantly associated with relapse and survival (P = 0.004 for PFS and P = 0.037 for OS). No PFS or OS benefit was seen with STR versus biopsy/no sampling (P = 0.58 for PFS, P = 0.59 for OS). For patients with JPAs and WHO grade II tumors, the 15-year PFS was 18.8 and 22.2% (P = 0.95) and 15-year OS was 73.7 and 55.6% (P = 0.17), respectively. Upfront TPDCV for children with hypothalamic/chiasmatic LGGs resulted in 15-year OS of 71.2% and 15-year PFS of 23.4%. No survival benefit is demonstrated for greater extent of resection. Age is a significant prognostic factor for progression and survival. PMID:20221671

  7. Hamartoma of the urinary bladder in a 15-year-old boy

    PubMed Central

    Al Shahwani, Noora; Alnaimi, Abdulla Rashid; Ammar, Adham; Al-ahdal, Esra M.

    2016-01-01

    Hamartoma of the bladder is an unusual entity described in only eleven patients to date. It may present as painless hematuria, irritative urinary tract symptoms, or inability to void or it may be diagnosed incidentally. Hamartoma of the bladder may be isolated or occur as part of a syndrome. No isolated bladder hamartoma to date has shown malignant potential. We describe here a bladder hamartoma in a 15-year-old boy. PMID:27274896

  8. A 15-year-old boy with snoring and molar tooth sign.

    PubMed

    El-Kersh, Karim; Senthilvel, Egambaram

    2015-04-01

    A 15-year-old boy presented for evaluation of snoring and sleep-disordered breathing. The parents noted that the patient snored every night and that he had episodes when he stopped breathing, ending with gasping for air. He had no history of sleep walking, night terrors, tongue biting, or seizures. The patient had two healthy siblings, but he had a history of intellectual disability and developmental delay. The patient had a history of adenotonsillectomy. PMID:25846539

  9. Marine mammal strandings and environmental changes: a 15-year study in the St. Lawrence ecosystem.

    PubMed

    Truchon, Marie-Hélène; Measures, Lena; L'Hérault, Vincent; Brêthes, Jean-Claude; Galbraith, Peter S; Harvey, Michel; Lessard, Sylvie; Starr, Michel; Lecomte, Nicolas

    2013-01-01

    Understanding the effects of climatic variability on marine mammals is challenging due to the complexity of ecological interactions. We used general linear models to analyze a 15-year database documenting marine mammal strandings (1994-2008; n = 1,193) and nine environmental parameters known to affect marine mammal survival, from regional (sea ice) to continental scales (North Atlantic Oscillation, NAO). Stranding events were more frequent during summer and fall than other seasons, and have increased since 1994. Poor ice conditions observed during the same period may have affected marine mammals either directly, by modulating the availability of habitat for feeding and breeding activities, or indirectly, through changes in water conditions and marine productivity (krill abundance). For most species (75%, n = 6 species), a low volume of ice was correlated with increasing frequency of stranding events (e.g. R(2)adj = 0.59, hooded seal, Cystophora cristata). This likely led to an increase in seal mortality during the breeding period, but also to increase habitat availability for seasonal migratory cetaceans using ice-free areas during winter. We also detected a high frequency of stranding events for mysticete species (minke whale, Balaenoptera acutorostrata) and resident species (beluga, Delphinapterus leucas), correlated with low krill abundance since 1994. Positive NAO indices were positively correlated with high frequencies of stranding events for resident and seasonal migratory cetaceans, as well as rare species (R(2)adj = 0.53, 0.81 and 0.34, respectively). This contrasts with seal mass stranding numbers, which were negatively correlated with a positive NAO index. In addition, an unusual multiple species mortality event (n = 114, 62% of total annual mortality) in 2008 was caused by a harmful algal bloom. Our findings provide an empirical baseline in understanding marine mammal survival when faced with climatic variability. This is a promising

  10. Marine Mammal Strandings and Environmental Changes: A 15-Year Study in the St. Lawrence Ecosystem

    PubMed Central

    Truchon, Marie-Hélène; Measures, Lena; L’Hérault, Vincent; Brêthes, Jean-Claude; Galbraith, Peter S.; Harvey, Michel; Lessard, Sylvie; Starr, Michel; Lecomte, Nicolas

    2013-01-01

    Understanding the effects of climatic variability on marine mammals is challenging due to the complexity of ecological interactions. We used general linear models to analyze a 15-year database documenting marine mammal strandings (1994–2008; n = 1,193) and nine environmental parameters known to affect marine mammal survival, from regional (sea ice) to continental scales (North Atlantic Oscillation, NAO). Stranding events were more frequent during summer and fall than other seasons, and have increased since 1994. Poor ice conditions observed during the same period may have affected marine mammals either directly, by modulating the availability of habitat for feeding and breeding activities, or indirectly, through changes in water conditions and marine productivity (krill abundance). For most species (75%, n = 6 species), a low volume of ice was correlated with increasing frequency of stranding events (e.g. R2adj = 0.59, hooded seal, Cystophora cristata). This likely led to an increase in seal mortality during the breeding period, but also to increase habitat availability for seasonal migratory cetaceans using ice-free areas during winter. We also detected a high frequency of stranding events for mysticete species (minke whale, Balaenoptera acutorostrata) and resident species (beluga, Delphinapterus leucas), correlated with low krill abundance since 1994. Positive NAO indices were positively correlated with high frequencies of stranding events for resident and seasonal migratory cetaceans, as well as rare species (R2adj = 0.53, 0.81 and 0.34, respectively). This contrasts with seal mass stranding numbers, which were negatively correlated with a positive NAO index. In addition, an unusual multiple species mortality event (n = 114, 62% of total annual mortality) in 2008 was caused by a harmful algal bloom. Our findings provide an empirical baseline in understanding marine mammal survival when faced with climatic variability. This is a promising

  11. A New 15-year Multisite AWS Temperature and Pressure Record for West Antarctica

    NASA Astrophysics Data System (ADS)

    Reusch, D. B.; Alley, R. B.

    2002-05-01

    spanning West Antarctica from the Ross Island area (Ferrell) to the Bellingshausen Sea region (Siple Station) for the period 1979-1993. EOF analysis of the 15-year temperature records suggests significant (though as yet uninterpreted) differences between the easterly/ice-sheet (Siple Station and Byrd) and westerly/ice-shelf (Lettau, Marilyn, Ferrell) stations. Short-term trends in annual high and low temperatures are also present. These results support high confidence in the ANN-based predictions from ECMWF data for periods where AWS data are unavailable, e.g., before installation. ANNs thus provide a means to expand our surface meteorological records significantly in West Antarctica.

  12. ASTER VNIR 15 years growth to the standard imaging radiometer in remote sensing

    NASA Astrophysics Data System (ADS)

    Hiramatsu, Masaru; Inada, Hitomi; Kikuchi, Masakuni; Sakuma, Fumihiro

    2015-10-01

    The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) Visible and Near Infrared Radiometer (VNIR) is the remote sensing equipment which has 3 spectral bands and one along-track stereoscopic band radiometer. ASTER VNIR's planned long life design (more than 5 years) is successfully achieved. ASTER VNIR has been imaging the World-wide Earth surface multiband images and the Global Digital Elevation Model (GDEM). VNIR data create detailed world-wide maps and change-detection of the earth surface as utilization transitions and topographical changes. ASTER VNIR's geometric resolution is 15 meters; it is the highest spatial resolution instrument on NASA's Terra spacecraft. Then, ASTER VNIR was planned for the geometrical basis map makers in Terra instruments. After 15-years VNIR growth to the standard map-maker for space remote-sensing. This paper presents VNIR's feature items during 15-year operation as change-detection images , DEM and calibration result. VNIR observed the World-wide Earth images for biological, climatological, geological, and hydrological study, those successful work shows a way on space remote sensing instruments. Still more, VNIR 15 years observation data trend and onboard calibration trend data show several guide or support to follow-on instruments.

  13. Tobacco use among students aged 13-15 years--Baghdad, Iraq, 2008.

    PubMed

    2009-04-01

    In 2008, Iraq's parliament ratified the World Health Organization Framework Convention on Tobacco Control (WHO FCTC), which obligates participants to establish tobacco use monitoring, surveillance, and evaluation systems. Lack of data on adolescent tobacco use in Iraq led the Ministry of Health (MOH) to conduct the Global Youth Tobacco Survey (GYTS) in Baghdad in 2008. GYTS is a school-based survey of students aged 13--15 years that is self-administered in classes in selected schools. As in most Middle East countries, tobacco use in Iraq takes the form of cigarettes and shisha. Based on GYTS results, 7.4% of students aged 13--15 years reported having ever smoked cigarettes, 12.9% had ever smoked shisha, 3.2% currently smoked cigarettes, and 6.3% currently smoked shisha. Among never smokers aged 13--15 years, 13.0% reported they were likely to initiate cigarette smoking in the next year. Future declines in adolescent tobacco use in Iraq (and Baghdad) could be enhanced by expanding existing tobacco control programs to include prevention and cessation of the use of cigarettes and shisha, implementing measures that discourage adolescents who have never smoked from initiating tobacco use, expanding legislation to ban exposure to secondhand smoke in all indoor workplaces, and enacting legislation banning pro-tobacco advertising and sponsorship.

  14. VII. NIH Toolbox Cognition Battery (CB): factor structure for 3 to 15 year olds.

    PubMed

    Mungas, Dan; Widaman, Keith; Zelazo, Philip David; Tulsky, David; Heaton, Robert K; Slotkin, Jerry; Blitz, David L; Gershon, Richard C

    2013-08-01

    Confirmatory factor analysis was used the evaluate the dimensional structure underlying the NIH Toolbox Cognition Battery (CB) and the measures chosen to serve as concurrent validity criteria for the NIH Toolbox CB. These results were used to evaluate the convergent and discriminant validity of the CB in children ranging from 3 to 15 years of age. Results were evaluated separately for a 3- to 6-year-old group and a 8- to 15-year-old group because different validation measures were used in these age groups. Three distinct dimensions were found for the 3- to 6-year-old group: Vocabulary, Reading, and Fluid Abilities. Five dimensions were found for 8-15 year olds: Vocabulary, Reading, Episodic Memory, Working Memory, and Executive Function/Processing Speed. CB measures and their validation analogues consistently defined common factors in a pattern that broadly supported the convergent and discriminant validity of the CB, but results showed higher intercorrelation and less differentiation of cognitive dimensions in younger than in older children and in older children compared with adults. Age was strongly related to the cognitive dimensions underlying test performance in both groups of children and results are consistent with broader literature showing increasing differentiation of cognitive abilities associated with the rapid brain development that occurs from early childhood into adulthood.

  15. Tinnitus as an early indicator of permanent hearing loss. A 15 year longitudinal study of noise exposed workers.

    PubMed

    Griest, S E; Bishop, P M

    1998-07-01

    A retrospective study was designed to evaluate tinnitus (ringing or other sounds in the ears or head) as a potential early indicator of permanent hearing loss in a population of noise exposed workers. Data were examined from 91 male employees working in environments with noise levels ranging from 8 hour time weighted averages of 85 to 101 dBA over a period of 15 years. Results of annual audiometric testing were obtained as part of an ongoing hearing conservation program conducted since 1971 by ESCO Corporation, a steel foundry located in the Portland, Oregon metropolitan area. Results indicate the prevalence of tinnitus increases more than two and one half times for workers experiencing maximum threshold shifts > or = 15 decibels in hearing level (dBHL). Results also provide evidence that reports of tinnitus at the time of annual audiometric testing may be useful in identifying workers at greater risk for developing significant shifts in hearing thresholds. PMID:9748912

  16. Guidewire path tracking and segmentation in 2D fluoroscopic time series using device paths from previous frames

    NASA Astrophysics Data System (ADS)

    Wagner, Martin G.; Strother, Charles M.; Mistretta, Charles A.

    2016-03-01

    Recent efforts to perform a 3D reconstruction of interventional devices such as guidewires from monoplane and biplane fluoroscopic images require the segmentation of the exact device path in the respective 2D projection images. The segmentation of the device in low dose fluoroscopy images can be challenging since noise and motion artifacts degrade the image quality. Additionally, extracting the device path from the segmented region may result in ambiguous results due to overlapping device parts or discontinuities in the device segmentation. The purpose of this work is to present a novel guidewire tracking and segmentation algorithm, which segments the device region based on three different features based on a ridge detection filter, noise reduction for curvilinear structures as well as an a priori probability map. The features are calculated from background subtracted as well as unsubtracted fluoroscopic images. The device path extraction is based on a topology preserving thinning algorithm followed by a path search, which minimizes a cost function based on distance and directional difference between adjacent segments as well as the similarity to the device path extracted from the previous frame. The quantitative evaluation was performed using 7 data sets acquired from a canine study. Device shapes with different complexities are compared to semi-automatic segmentations. An average segmentation accuracy of 0.50 0.41 mm was achieved where each point along the device was compared to the point on the reference device centerline with the same distance to the device tip. In all cases the device path could be resolved correctly, which would allow a more accurate and reliable reconstruction of the 3D path of the device.

  17. Reference Frames and Relativity.

    ERIC Educational Resources Information Center

    Swartz, Clifford

    1989-01-01

    Stresses the importance of a reference frame in mechanics. Shows the Galilean transformation in terms of relativity theory. Discusses accelerated reference frames and noninertial reference frames. Provides examples of reference frames with diagrams. (YP)

  18. Locus of Control: Relation to Schizophrenia, to Recovery, and to Depression and Psychosis - A 15-Year Longitudinal Study

    PubMed Central

    Harrow, Martin; Hansford, Barry G.; Astrachan-Fletcher, Ellen B.

    2009-01-01

    Purpose The present prospectively designed 15-year longitudinal research was conducted to study whether locus of control is linked to diagnosis, to major symptoms, to functioning and recovery, and to personality for schizophrenia patients, depressive patients, and patients with other major disorders. Procedure The research studied 128 patients from the Chicago Follow-up Study at the acute phase and reassessed them 5 times over a 15-year period. Patients were evaluated on locus of control, global outcome, recovery, premorbid developmental achievements, psychosis, diagnosis, depression, and personality variables. Results 1.) After the acute phase, schizophrenia patients were not more external than other diagnostic groups. 2.) Internality is associated with increased recovery in schizophrenia (p<.05). 3.) A more external locus of control was related to depression (p=.01). 4.) The relationship between externality and psychosis was significant (p<.05). Conclusions In severe psychiatric disorders a more external locus of control is not specific to schizophrenia and after the acute phase is not associated with one particular diagnostic group. A more external locus of control is related to fewer periods of recovery, to both depressed mood and psychosis, and to various aspects of personality (p<.05). PMID:19573929

  19. Hospitalization Incidence, Mortality, and Seasonality of Common Respiratory Viruses Over a Period of 15 Years in a Developed Subtropical City

    PubMed Central

    Chan, Paul K.S.; Tam, Wilson W.S.; Lee, Tsz Cheung; Hon, Kam Lun; Lee, Nelson; Chan, Martin C.W.; Mok, Hing Yim; Wong, Martin C.S.; Leung, Ting Fan; Lai, Raymond W.M.; Yeung, Apple C.M.; Ho, Wendy C.S.; Nelson, E. Anthony S.; Hui, David S.C.

    2015-01-01

    Abstract Information on respiratory viruses in subtropical region is limited. Incidence, mortality, and seasonality of influenza (Flu) A/B, respiratory syncytial virus (RSV), adenovirus (ADV), and parainfluenza viruses (PIV) 1/2/3 in hospitalized patients were assessed over a 15-year period (1998–2012) in Hong Kong. Male predominance and laterally transversed J-shaped distribution in age-specific incidence was observed. Incidence of Flu A, RSV, and PIV decreased sharply from infants to toddlers; whereas Flu B and ADV increased slowly. RSV conferred higher fatality than Flu, and was the second killer among hospitalized elderly. ADV and PIV were uncommon, but had the highest fatality. RSV, PIV 2/3 admissions increased over the 15 years, whereas ADV had decreased significantly. A “high season,” mainly contributed by Flu, was observed in late-winter/early-spring (February–March). The “medium season” in spring/summer (April–August) was due to Flu and RSV. The “low season” in late autumn/winter (October–December) was due to PIV and ADV. Seasonality varied between viruses, but predictable distinctive pattern for each virus existed, and temperature was the most important associating meteorological variable. Respiratory viruses exhibit strong sex- and age-predilection, and with predictable seasonality allowing strategic preparedness planning. Hospital-based surveillance is crucial for real-time assessment on severity of new variants. PMID:26579810

  20. Picosecond (picoframe) framing camera evaluations.

    PubMed

    Liu, Y; Sibbett, W; Walker, D R

    1992-03-01

    Detailed theoretical evaluations of picoframe-I- and II-type framing cameras are presented, and predicted performance characteristics are compared with experimental results. The methods of theoretical simulations are described, and a suite of computer programs was developed. The theoretical analyses indicate that the existence of fringe fields in the vicinity of the deflectors is the main factor that limits the dynamic spatial resolutions and frame times of these particular designs of framing camera, and possible refinements are outlined. PMID:20720702

  1. 15 years later: on the physics of high-rise building collapses

    NASA Astrophysics Data System (ADS)

    Jones, Steven; Korol, Robert; Szamboti, Anthony; Walter, Ted

    2016-08-01

    On September 11, 2001, the world witnessed the total collapse of three large steel-framed high-rises. Since then, scientists and engineers have been working to understand why and how these unprecedented structural failures occurred.

  2. The framing of drivers' route choices when travel time information is provided under varying degrees of cognitive load.

    PubMed

    Katsikopoulos, K V; Duse-Anthony, Y; Fisher, D L; Duffy, S A

    2000-01-01

    In two experiments, participants chose between staying on a main route with a certain travel time and diverting to an alternative route that could take a range of travel times. In the first experiment, travel time information was displayed on a sheet of paper to participants seated at a desk. In the second experiment, the same information was displayed in a virtual environment through which participants drove. Overall, participants were risk-averse when the average travel time along the alternative route was shorter than the certain travel time of the main route but risk-seeking when the average travel time of the alternative route was longer than the certain travel time along the main route. In the second experiment, in which cognitive load was higher, participants simplified their decision-making strategies. A simple probabilistic model describes the risk-taking behavior and the load effects. Actual or potential applications of this research include the development of efficient travel time information systems for drivers.

  3. 2-20 ns interframe time 2-frame 6.151 keV x-ray imaging on the recently upgraded Z Accelerator: A progress report

    SciTech Connect

    Bennett, G. R.; Smith, I. C.; Shores, J. E.; Sinars, D. B.; Robertson, G.; Atherton, B. W.; Jones, M. C.; Porter, J. L.

    2008-10-15

    When used for the production of an x-ray imaging backlighter source on Sandia National Laboratories' recently upgraded 26 MA Z Accelerator, the terawatt-class, multikilojoule, 526.57 nm Z-Beamlet laser (ZBL) [P. K. Rambo et al., Appl. Opt. 44, 2421 (2005)], in conjunction with the 6.151 keV (1s{sup 2}-1s2p triplet line of He-like Mn) curved-crystal imager [D. B. Sinars et al., Rev. Sci. Instrum. 75, 3672 (2004); G. R. Bennett et al., Rev. Sci. Instrum. 77, 10E322 (2006)], is capable of providing a high quality x radiograph per Z shot for inertial confinement fusion (ICF), complex hydrodynamics, and other high-energy-density physics experiments. For example, this diagnostic has recently afforded microgram-scale mass perturbation measurements on an imploding ignition-scale 1 mg ICF capsule [G. R. Bennett et al., Phys. Rev. Lett. 99, 205003 (2007)], where the perturbation was initiated by a surrogate deuterium-tritium (DT) fuel fill tube. Using an angle-time multiplexing technique, ZBL now has the capability to provide two spatially and temporally separated foci in the Z chamber, allowing 'two-frame' imaging to be performed, with an interframe time range of 2-20 ns. This multiplexing technique allows the full area of the four-pass amplifiers to be used for the two pulses, rather than split the amplifiers effectively into two rectangular sections, with one leg delayed with respect to the other, which would otherwise double the power imposed onto the various optics thereby halving the damage threshold, for the same irradiance on target. The 6.151 keV two frame technique has recently been used to image imploding wire arrays, using a 7.3 ns interframe time. The diagnostic will soon be converted to operate with p-rather than s-polarized laser light for enhanced laser absorption in the Mn foil, plus other changes (e.g., operation at the possibly brighter 6.181 keV Mn 1s{sup 2}-1s2p singlet line), to increase x-ray yields. Also, a highly sensitive inline multiframe ultrafast

  4. 2-20 ns interframe time 2-frame 6.151 keV x-ray imaging on the recently upgraded Z Accelerator: A progress report

    NASA Astrophysics Data System (ADS)

    Bennett, G. R.; Smith, I. C.; Shores, J. E.; Sinars, D. B.; Robertson, G.; Atherton, B. W.; Jones, M. C.; Porter, J. L.

    2008-10-01

    When used for the production of an x-ray imaging backlighter source on Sandia National Laboratories' recently upgraded 26MA Z Accelerator, the terawatt-class, multikilojoule, 526.57nm Z-Beamlet laser (ZBL) [P. K. Rambo et al., Appl. Opt. 44, 2421 (2005)], in conjunction with the 6.151keV (1s2-1s2p triplet line of He-like Mn) curved-crystal imager [D. B. Sinars et al., Rev. Sci. Instrum. 75, 3672 (2004); G. R. Bennett et al., Rev. Sci. Instrum. 77, 10E322 (2006)], is capable of providing a high quality x radiograph per Z shot for inertial confinement fusion (ICF), complex hydrodynamics, and other high-energy-density physics experiments. For example, this diagnostic has recently afforded microgram-scale mass perturbation measurements on an imploding ignition-scale 1mg ICF capsule [G. R. Bennett et al., Phys. Rev. Lett. 99, 205003 (2007)], where the perturbation was initiated by a surrogate deuterium-tritium (DT) fuel fill tube. Using an angle-time multiplexing technique, ZBL now has the capability to provide two spatially and temporally separated foci in the Z chamber, allowing "two-frame" imaging to be performed, with an interframe time range of 2-20ns. This multiplexing technique allows the full area of the four-pass amplifiers to be used for the two pulses, rather than split the amplifiers effectively into two rectangular sections, with one leg delayed with respect to the other, which would otherwise double the power imposed onto the various optics thereby halving the damage threshold, for the same irradiance on target. The 6.151keV two frame technique has recently been used to image imploding wire arrays, using a 7.3ns interframe time. The diagnostic will soon be converted to operate with p-rather than s-polarized laser light for enhanced laser absorption in the Mn foil, plus other changes (e.g., operation at the possibly brighter 6.181keV Mn 1s2-1s2p singlet line), to increase x-ray yields. Also, a highly sensitive inline multiframe ultrafast (1ns gate time

  5. Synchronization as a biological, psychological and social mechanism to create common time: A theoretical frame and a single case study.

    PubMed

    Bao, Yan; Pöppel, Ernst; Wang, Lingyan; Lin, Xiaoxiong; Yang, Taoxi; Avram, Mihai; Blautzik, Janusch; Paolini, Marco; Silveira, Sarita; Vedder, Aline; Zaytseva, Yuliya; Zhou, Bin

    2015-12-01

    Synchronizing neural processes, mental activities, and social interactions is considered to be fundamental for the creation of temporal order on the personal and interpersonal level. Several different types of synchronization are distinguished, and for each of them examples are given: self-organized synchronizations on the neural level giving rise to pre-semantically defined time windows of some tens of milliseconds and of approximately 3 s; time windows that are created by synchronizing different neural representations, as for instance in aesthetic appreciations or moral judgments; and synchronization of biological rhythms with geophysical cycles, like the circadian clock with the 24-hr rhythm of day and night. For the latter type of synchronization, an experiment is described that shows the importance of social interactions for sharing or avoiding common time. In a group study with four subjects being completely isolated together for 3 weeks from the external world, social interactions resulted both in intra- and interindividual circadian synchronization and desynchronization. A unique phenomenon in circadian regulation is described, the "beat phenomenon," which has been made visible by the interaction of two circadian rhythms with different frequencies in one body. The separation of the two physiological rhythms was the consequence of social interactions, that is, by the desire of a subject to share and to escape common time during different phases of the long-term experiment. The theoretical arguments on synchronization are summarized with the general statement: "Nothing in cognitive science makes sense except in the light of time windows." The hypothesis is forwarded that time windows that express discrete timing mechanisms in behavioral control and on the level of conscious experiences are the necessary bases to create cognitive order, and it is suggested that time windows are implemented by neural oscillations in different frequency domains. PMID:26663630

  6. Synchronization as a biological, psychological and social mechanism to create common time: A theoretical frame and a single case study.

    PubMed

    Bao, Yan; Pöppel, Ernst; Wang, Lingyan; Lin, Xiaoxiong; Yang, Taoxi; Avram, Mihai; Blautzik, Janusch; Paolini, Marco; Silveira, Sarita; Vedder, Aline; Zaytseva, Yuliya; Zhou, Bin

    2015-12-01

    Synchronizing neural processes, mental activities, and social interactions is considered to be fundamental for the creation of temporal order on the personal and interpersonal level. Several different types of synchronization are distinguished, and for each of them examples are given: self-organized synchronizations on the neural level giving rise to pre-semantically defined time windows of some tens of milliseconds and of approximately 3 s; time windows that are created by synchronizing different neural representations, as for instance in aesthetic appreciations or moral judgments; and synchronization of biological rhythms with geophysical cycles, like the circadian clock with the 24-hr rhythm of day and night. For the latter type of synchronization, an experiment is described that shows the importance of social interactions for sharing or avoiding common time. In a group study with four subjects being completely isolated together for 3 weeks from the external world, social interactions resulted both in intra- and interindividual circadian synchronization and desynchronization. A unique phenomenon in circadian regulation is described, the "beat phenomenon," which has been made visible by the interaction of two circadian rhythms with different frequencies in one body. The separation of the two physiological rhythms was the consequence of social interactions, that is, by the desire of a subject to share and to escape common time during different phases of the long-term experiment. The theoretical arguments on synchronization are summarized with the general statement: "Nothing in cognitive science makes sense except in the light of time windows." The hypothesis is forwarded that time windows that express discrete timing mechanisms in behavioral control and on the level of conscious experiences are the necessary bases to create cognitive order, and it is suggested that time windows are implemented by neural oscillations in different frequency domains.

  7. Traumatic Dental Injuries Among 12-15-Year-Old-School Children in Panchkula

    PubMed Central

    Chopra, Amandeep; Lakhanpal, Manav; Rao, NC; Gupta, Nidhi; Vashisth, Shelja

    2014-01-01

    Background: Traumatic dental injury (TDI) in children and adolescents has become one of the most serious dental public health problems. Despite such a high prevalence of dental trauma, very less attention has been paid to TDI, its etiology, and prevention. Objectives: To determine the prevalence of anterior tooth traumatic dental injuries in 12-15-year-old school children of Panchkula district, India, and to find any correlation with the cause, gender, extent of overbite as well as over-jet, and previous treatment. Patients and Methods: A multistage sample of 12-15-year-old school children (n = 810) in Panchkula district, Haryana, was selected. The children were screened using WHO criteria for oral examination and a trained dental surgeon examined the children. Those with clinical TDI were examined further for the type of traumatic injuries using Elis classification modified by Holland. Overjet and overbite were recorded. After examination, questions regarding the cause of trauma and its treatment were asked. Data were subjected to statistical analysis using the Chi square and Mantel-Haenszel tests by SPSS version 20.0. Results: The results showed that out of 810 children, 86 (10.2 %) had TDI. Males had higher prevalence of trauma than females (P < 0.05). The common cause of trauma was fall (51.11%) followed by sports injuries (41.86%). Enamel-dentin fracture without pulpal involvement was the most common type of trauma and the most frequent involved teeth were maxillary central incisors. A significant association was observed between overjet and overbite and trauma. Only 3.5% of the children affected with trauma had received treatment. Conclusions: The prevalence of traumatic injuries to permanent incisors in 12-15-year-old Panchkula school children was relatively high. TDI was associated with gender, overjet, and lip competence. There was a great unmet treatment need. PMID:25032172

  8. Epidemiological Follow-up 15 Years after the Breast Cancer Scandal in Essen.

    PubMed

    Hauth, E A M; Berkemeyer, S; Jaeger, H; Forsting, M; Hoffmann, B; Jöckel, K-H

    2012-06-01

    Purpose: In the years 1993-1996 a number of presumably false-positive breast cancer diagnoses were made by a pathologist in Essen. A follow-up, undertaken 15 years later, investigated how many women had tumour recurrence and/or metastasis or had died from breast cancer. Material and Methods: A total of 151 (68 %) out of 222 women could be traced. One hundred and forty-seven (66.2 %) of the 222 women were alive. The observed survival rate, number of recurrences and/or metastases, and number of deaths from breast cancer were compared with data from the Munich Tumour Registry. The number of breast cancer cases among daughters of the affected women was ascertained. Results: The total observed survival rate at follow-up after 15 years was 93 %, a much higher figure than the survival rate of 45 % given by the Munich Tumour Registry. Recurrence and/or metastasis or death from breast cancer occurred in 9/222 cases (4.1 %). The incidence for these events calculated according to data from the Munich Tumour Registry is 13 %. Two daughters (2.2 %) out of a total of 90 were diagnosed with breast cancer whereas, according to the German Cancer Research Centre, the expected rate would have been between 5 and 10 %. Conclusions: The results of our follow-up after 15 years show that more women survived than expected and that the number of recurrences and/or metastases and deaths due to breast cancer was lower than expected. Fewer daughters of affected women were diagnosed with breast cancer than expected. These results support our suspicion that not all women diagnosed with breast cancer by a pathologist in Essen actually had breast cancer.

  9. Gouty arthritis in a 15-year-old girl with Bartter's syndrome.

    PubMed

    Derakhshan, Nima; Derakhshan, Dorna; Basiratnia, Mitra; Fallahzadeh, Mohammad Hossein; Hashemi, Ghamar; Derakhshan, Ali

    2010-11-01

    A 15-year-old girl, a known case of Bartter's syndrome (BS) for 7 years, developed severe pain in her right knee and right and left ankle. Her older sister had BS and developed end-stage renal disease (ESRD) at the age of 14 years. Her serum uric acid was 12.6 mg/dL, 6 months ago, and 15.4 mg/dL in her recent lab data. Hyperuricemia and gouty arthritis are commonly seen in adults with BS, but to our knowledge there is no report of gouty arthritis in pediatric literature.

  10. Hemoptysis workup before embolization: single-center experience with a 15-year period follow-up.

    PubMed

    de Gregorio, Miguel A; Medrano, Joaquin; Laborda, Alicia; Higuera, Teresa

    2007-12-01

    The objective of this work was to present our experience in arterial embolization in the endovascular treatment of massive hemoptysis and remark on the importance of the workup before embolization. We present some clinical aspects to keep in mind before carrying out a bronchial embolization in a patient with severe hemoptysis. The main causes of hemoptysis are presented, as well as diagnosis means and the most important therapeutic procedures aimed to stabilize the patient who will undergo a bronchial arterial embolization. Likewise, we present our own experience with 401 patients with over a 15-year period of follow-up. PMID:18572140

  11. Visual illusions on the Internet: 15 years of change in technology and user behavior.

    PubMed

    Bach, Michael

    2014-01-01

    Abstract. Looking back over 15 years of demonstrating visual phenomena and optical illusions on the Internet, I will discuss two major topics. The first concerns the methodology used to present interactive visual experiments on the web, with respect to (a) wide accessibility, ie independent of browser and platform, (b) capable and elegant graphic user interface, (c) sufficient computational power, (d) ease of development and, finally, (e) future-proofing in an ever-changing online environment. The second major topic addresses some aspects of user behaviour, mainly temporal patterns (eg changes over weeks. years, long-term), which reveal that there are more visitors during office hours.

  12. [Coexistence of Crohn disease and Wegener granulomatosis in a 15-year-old patient].

    PubMed

    Sieczkowska, Agnieszka; Lewandowski, Piotr; Szumera, Małgorzata; Kamińska, Barbara

    2011-01-01

    Crohn disease is being diagnosed more and more frequently in children and teenagers. Clinical symptoms are mainly related to the gastrointestinal tract, however there are many reports in the literature about the coexistence of Crohn disease with other autoimmunological disorders such as celiac disease, autoimmune hypothyroidism, systemic lupus erythematosus and Wegener granulomatosis. We report a 15-year-old patient with Crohn disease who also developed Wegener granulomatosis. The presented case illustrates the difficulties in establishing the diagnosis when symptoms of the original disease are superimposed on symptoms of a different disorder. PMID:22516704

  13. Adenocarcinoma at ureterosigmoidostomy junction in a renal transplant recipient 15 years after conversion to ileal conduit.

    PubMed

    Weinstein, T; Zevin, D; Kyzer, S; Korzets, A; Halperin, M; Luria, B; Levi, J

    1995-08-01

    In recent years, adenocarcinoma of the colon mucosa has become a recognized complication of ureterosigmoidostomy and in most cases the tumor arises at the site of ureterocolonic anastomosis. We report a case of a 29-year-old renal transplant recipient who developed two colonic carcinomas at the site of ureterosigmoidostomy 25 years after the urinary diversion and 15 years after conversion to an ileal conduit. This case emphasizes the need for a careful life-long follow-up of all patients who undergo ureterosigmoidostomy. PMID:8529301

  14. A Summer School for High School students: a 15 years experience.

    NASA Astrophysics Data System (ADS)

    Zamorano, Nelson

    2004-03-01

    During the last 15 years we have been offering a summer course (usually lasting four weeks) to interested high school students. In this work we summarizes its evolution, mainly of the physics course, during these years. The summer school started with 45 students for a physics course, and now we have 4000 students applying to the different subjects offered. In the physics course, we have offered, from the very beginning, a numerical complement to the students, where we use maple, excel and Interactive Physics. Starting from this experience we have derived to winter school for younger students and collective experiments like measuring the Earth radious using the Eratosthenes method.

  15. [Health surveillance in a steel making industry with electric arc furnace: 15 years of experience].

    PubMed

    Corti, P

    2012-01-01

    This paper analyzes the results of health surveillance carried out in an electric steel mill for 15 years. We have analyzed the trend of audiometry, spirometry and main indicators of exposure to chemical risk: serum lead, urinary OH-pyrene, erythrocyte ZPP, and the results of risk assessment of stress work related. The analyses of the trend of audiometry, spirometry and biological monitoring shows an important improving in the working environment due to the progressive automation of production steps in the course of several years, consistent and correct use of DPI, information and training.

  16. Temporal Space Lymphatic Malformation in a 15-Year-Old Adolescent: An Extraordinary Case.

    PubMed

    Igoumenakis, Dimosthenis; Logothetis, Ioannis; Barmpagadaki, Alina; Ieromonachou, Panayotis; Mastorakis, George

    2016-07-01

    Lymphatic malformations-previously called lymphangiomas or cystic hygromas-are regarded as non-malignant primary disorders of the lymphatic system. They appear predominantly in infants and children, with 90 % of cases being diagnosed by the age of 2 years. Also, they constitute an infrequent entity, accounting for 5 % of all benign tumors in infants and children. In adults they are extremely rare. In the present article we present an extraordinary case of a lymphatic malformation that ensued in the temporal area of a 15-year old adolescent.

  17. Plummer-Vinson syndrome in a 15-year-old boy.

    PubMed

    Dinler, Gönül; Tander, Burak; Kalayci, Ayhan Gazi; Rizalar, Riza

    2009-01-01

    Plummer-Vinson syndrome presents as a classical triad of dysphagia, iron deficiency anemia and upper esophageal web(s). The syndrome usually occurs in adults, and is rare in childhood. We report a case of this syndrome occurring in a 15-year-old boy. He presented with dysphagia and anemia. Radiological examination showed the presence of webs at the cervical esophagus. The boy was treated with endoscopic balloon dilation and iron supplementation and remains in good general condition six months after the treatment.

  18. Temporal Space Lymphatic Malformation in a 15-Year-Old Adolescent: An Extraordinary Case.

    PubMed

    Igoumenakis, Dimosthenis; Logothetis, Ioannis; Barmpagadaki, Alina; Ieromonachou, Panayotis; Mastorakis, George

    2016-07-01

    Lymphatic malformations-previously called lymphangiomas or cystic hygromas-are regarded as non-malignant primary disorders of the lymphatic system. They appear predominantly in infants and children, with 90 % of cases being diagnosed by the age of 2 years. Also, they constitute an infrequent entity, accounting for 5 % of all benign tumors in infants and children. In adults they are extremely rare. In the present article we present an extraordinary case of a lymphatic malformation that ensued in the temporal area of a 15-year old adolescent. PMID:27408452

  19. [Relapse of bleeding ulcer in a 15 year-old boy with collagenous gastritis].

    PubMed

    Haase, Anne-Mette; Kelsen, Jens

    2012-06-18

    Collagenous gastritis (CG) is a rare disorder. Two patient groups are known: 1) Children and young adults, presenting with anaemia and abdominal pain, and 2) adults presenting with watery diarrhoea. In the latter group, CG is frequently associated with collagenous colitis and/or coeliac disease. This case concerns a 15-year-old boy with a bleeding ulcer. The biopsies from corpus ventriculi showed a thickened subepithelial collagen band (> 10 micrometres), and the patient was diagnosed with CG. Ulcers are rarely linked to CG. CG should be considered when ulcers are found in children and young adults. PMID:22713227

  20. A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells.

    PubMed

    Müller, Martin; Schröer, Jana; Azoitei, Ninel; Eiseler, Tim; Bergmann, Wendy; Köhntop, Ralf; Lin, Qiong; Costa, Ivan G; Zenke, Martin; Genze, Felicitas; Weidgang, Clair; Seufferlein, Thomas; Liebau, Stefan; Kleger, Alexander

    2015-01-01

    The protein kinase D isoenzymes PKD1/2/3 are prominent downstream targets of PKCs (Protein Kinase Cs) and phospholipase D in various biological systems. Recently, we identified PKD isoforms as novel mediators of tumour cell-endothelial cell communication, tumour cell motility and metastasis. Although PKD isoforms have been implicated in physiological/tumour angiogenesis, a role of PKDs during embryonic development, vasculogenesis and angiogenesis still remains elusive. We investigated the role of PKDs in germ layer segregation and subsequent vasculogenesis and angiogenesis using mouse embryonic stem cells (ESCs). We show that mouse ESCs predominantly express PKD2 followed by PKD3 while PKD1 displays negligible levels. Furthermore, we demonstrate that PKD2 is specifically phosphorylated/activated at the time of germ layer segregation. Time-restricted PKD2-activation limits mesendoderm formation and subsequent cardiovasculogenesis during early differentiation while leading to branching angiogenesis during late differentiation. In line, PKD2 loss-of-function analyses showed induction of mesendodermal differentiation in expense of the neuroectodermal germ layer. Our in vivo findings demonstrate that embryoid bodies transplanted on chicken chorioallantoic membrane induced an angiogenic response indicating that timed overexpression of PKD2 from day 4 onwards leads to augmented angiogenesis in differentiating ESCs. Taken together, our results describe novel and time-dependent facets of PKD2 during early cell fate determination. PMID:26148697

  1. A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells

    PubMed Central

    Müller, Martin; Schröer, Jana; Azoitei, Ninel; Eiseler, Tim; Bergmann, Wendy; Köhntop, Ralf; Lin, Qiong; Costa, Ivan G; Zenke, Martin; Genze, Felicitas; Weidgang, Clair; Seufferlein, Thomas; Liebau, Stefan; Kleger, Alexander

    2015-01-01

    The protein kinase D isoenzymes PKD1/2/3 are prominent downstream targets of PKCs (Protein Kinase Cs) and phospholipase D in various biological systems. Recently, we identified PKD isoforms as novel mediators of tumour cell-endothelial cell communication, tumour cell motility and metastasis. Although PKD isoforms have been implicated in physiological/tumour angiogenesis, a role of PKDs during embryonic development, vasculogenesis and angiogenesis still remains elusive. We investigated the role of PKDs in germ layer segregation and subsequent vasculogenesis and angiogenesis using mouse embryonic stem cells (ESCs). We show that mouse ESCs predominantly express PKD2 followed by PKD3 while PKD1 displays negligible levels. Furthermore, we demonstrate that PKD2 is specifically phosphorylated/activated at the time of germ layer segregation. Time-restricted PKD2-activation limits mesendoderm formation and subsequent cardiovasculogenesis during early differentiation while leading to branching angiogenesis during late differentiation. In line, PKD2 loss-of-function analyses showed induction of mesendodermal differentiation in expense of the neuroectodermal germ layer. Our in vivo findings demonstrate that embryoid bodies transplanted on chicken chorioallantoic membrane induced an angiogenic response indicating that timed overexpression of PKD2 from day 4 onwards leads to augmented angiogenesis in differentiating ESCs. Taken together, our results describe novel and time-dependent facets of PKD2 during early cell fate determination. PMID:26148697

  2. Athletic Classmates, Physical Self-Concept, and Free-Time Physical Activity: A Longitudinal Study of Frame of Reference Effects

    ERIC Educational Resources Information Center

    Trautwein, Ulrich; Gerlach, Erin; Ludtke, Oliver

    2008-01-01

    The systematic analysis of factors that promote or impede physical activity in children is an urgent task for educational researchers. The present study investigated the reciprocal relationship between physical self-concept, teacher-assigned grades in physical education classes, and free-time physical activity, and analyzed positive and negative…

  3. The integration of visual context information in facial emotion recognition in 5- to 15-year-olds.

    PubMed

    Theurel, Anne; Witt, Arnaud; Malsert, Jennifer; Lejeune, Fleur; Fiorentini, Chiara; Barisnikov, Koviljka; Gentaz, Edouard

    2016-10-01

    The current study investigated the role of congruent visual context information in the recognition of facial emotional expression in 190 participants from 5 to 15years of age. Children performed a matching task that presented pictures with different facial emotional expressions (anger, disgust, happiness, fear, and sadness) in two conditions: with and without a visual context. The results showed that emotions presented with visual context information were recognized more accurately than those presented in the absence of visual context. The context effect remained steady with age but varied according to the emotion presented and the gender of participants. The findings demonstrated for the first time that children from the age of 5years are able to integrate facial expression and visual context information, and this integration improves facial emotion recognition.

  4. International Conference on Population and Development at 15 Years: Achieving Sexual and Reproductive Health and Rights for All?

    PubMed Central

    Roseman, Mindy Jane

    2010-01-01

    Sexual and reproductive health remains the contentious concept it was at the 1994 United Nations International Conference on Population and Development (ICPD), held in Cairo, Egypt. In light of the recent 15-year review of ICPD, we suggest several areas where advocates, practitioners, and researchers can inform future progress for sexual and reproductive health. These include the following: improving measurement and accountability related to the evidence base for sexual and reproductive health, indicators of program success, and the tracking of resource flows; creating and renewing alliances to strengthen advocacy; and employing new resource mobilization strategies. Given the 20-year goals established at ICPD, now is the time to move toward finally achieving the sexual and reproductive health and rights agenda. PMID:20075310

  5. The integration of visual context information in facial emotion recognition in 5- to 15-year-olds.

    PubMed

    Theurel, Anne; Witt, Arnaud; Malsert, Jennifer; Lejeune, Fleur; Fiorentini, Chiara; Barisnikov, Koviljka; Gentaz, Edouard

    2016-10-01

    The current study investigated the role of congruent visual context information in the recognition of facial emotional expression in 190 participants from 5 to 15years of age. Children performed a matching task that presented pictures with different facial emotional expressions (anger, disgust, happiness, fear, and sadness) in two conditions: with and without a visual context. The results showed that emotions presented with visual context information were recognized more accurately than those presented in the absence of visual context. The context effect remained steady with age but varied according to the emotion presented and the gender of participants. The findings demonstrated for the first time that children from the age of 5years are able to integrate facial expression and visual context information, and this integration improves facial emotion recognition. PMID:27367301

  6. [Microsurgical management of male infertility in china: 15-year development and prospects].

    PubMed

    Peng, Jing; Li, Zheng; Tu, Xiang-An; Tian, Long; Zhang, Yan; Hong, Kai; Wang, Xiang; Yuan, Yi-Ming; Zhao, Lian-Ming; Ping, Ping; Zhou, Li-Xin; Liu, Yi-Dong; Mao, Xiang-Ming; Zhao, Fu-Jun; Chen, Xiang-Feng; Dong, Qiang; Sun, Zhong-Yi; Zhou, Tie; Liu, Zhi-yong; Sun, Xiang-Zhou; Jiang, Tao; Philip, S Li

    2014-07-01

    Male infertility is a common and complex disease in urology and andrology, and for many years there has been no effective surgical treatment. With the emergence of microsurgery and assisted reproductive medicine (IVF/ICSI), rapid development has been achieved in the treatment of male infertility. The Center for Male Reproductive Medicine and Microsurgery at Weill Cornell Medical College of Cornell University has been playing an important leading role in developing microsurgical techniques for the management of male infertility. The development of microsurgical treatment of male infertility in China has experienced the 3 periods of emerging, making, and boosting ever since its systematic introduction from Weill Cornell Medical College 15 years ago. At present, many Chinese hospitals have adopted microsurgery in the management of male infertility, which has contributed to the initial establishment of a microsurgical treatment system for male infertility in China. However, some deficiencies do exist concerning microsurgical treatment of male infertility, as in normalized technical training programs for competent surgeons, unified criteria for evaluation of surgical outcomes, and detailed postoperative follow-up data. This article presents an overview on the 15-year development of microsurgical management of male infertility in China, points out the existing deficiencies, and offers some propositions for the promotion of its development.

  7. Evaluation of antimicrobial resistance of Helicobacter pylori in the last 15 years in West Poland.

    PubMed

    Karpiński, Tomasz M; Andrzejewska, Ewa; Eder, Piotr; Linke, Krzysztof; Szkaradkiewicz, Andrzej

    2015-09-01

    Increasing resistance to drugs represents a serious problem in treatment of infections with Helicobacter pylori, providing cause of frequent therapeutic failures. Present study aimed at analysis of changes in resistance of H. pylori to antibiotics in West Poland within the recent 15 years. 108 strains of H. pylori were analysed, isolated from gastric mucosa of adult patients. Group 1 involved 66 strains isolated in years of 1998/1999. Group 2 comprised 42 isolates obtained in years of 2013/2014. Susceptibility to amoxicillin (AMX), clarithromycin (CL), tetracycline (TC) and metronidazole (MTZ) was determined by E-test (AB Biodisc). All strains on both studied groups were susceptible to AMX. In group 1 all strains proved to be susceptible to TC, while 9% and 36% of tested strains were resistant to CL and MTZ, respectively. By contrast, in group 2, 31% and 83% of strains were resistant to CL and MTZ, respectively. In parallel, 14% strains were found to be resistant to TC (according to EUCAST interpretations). In West Poland, within recent 15 years a dramatic increase was noted in H. pylori strains resistant to metronidazole. In parallel, a significant increase was noted in proportion of strains resistant to clarithromycin.

  8. EXPOSE-E: an ESA astrobiology mission 1.5 years in space.

    PubMed

    Rabbow, Elke; Rettberg, Petra; Barczyk, Simon; Bohmeier, Maria; Parpart, André; Panitz, Corinna; Horneck, Gerda; von Heise-Rotenburg, Ralf; Hoppenbrouwers, Tom; Willnecker, Rainer; Baglioni, Pietro; Demets, René; Dettmann, Jan; Reitz, Guenther

    2012-05-01

    The multi-user facility EXPOSE-E was designed by the European Space Agency to enable astrobiology research in space (low-Earth orbit). On 7 February 2008, EXPOSE-E was carried to the International Space Station (ISS) on the European Technology Exposure Facility (EuTEF) platform in the cargo bay of Space Shuttle STS-122 Atlantis. The facility was installed at the starboard cone of the Columbus module by extravehicular activity, where it remained in space for 1.5 years. EXPOSE-E was returned to Earth with STS-128 Discovery on 12 September 2009 for subsequent sample analysis. EXPOSE-E provided accommodation in three exposure trays for a variety of astrobiological test samples that were exposed to selected space conditions: either to space vacuum, solar electromagnetic radiation at >110 nm and cosmic radiation (trays 1 and 3) or to simulated martian surface conditions (tray 2). Data on UV radiation, cosmic radiation, and temperature were measured every 10 s and downlinked by telemetry. A parallel mission ground reference (MGR) experiment was performed on ground with a parallel set of hardware and samples under simulated space conditions. EXPOSE-E performed a successful 1.5-year mission in space.

  9. 200-BP-1 Prototype Hanford Barrier -- 15 Years of Performance Monitoring

    SciTech Connect

    Ward, Anderson L.; Draper, Kathryn E.; Link, Steven O.; Clayton, Ray E.

    2011-09-30

    Monitoring is an essential component of engineered barrier system design and operation. A composite capacitive cover, including a capillary break and an evapotranspiration (ET) barrier at the Hanford Site, is generating data that can be used to help resolve these issues. The prototype Hanford barrier was constructed over the 216-B-57 Crib in 1994 to evaluate surface-barrier constructability, construction costs, and physical and hydrologic performance at the field scale. The barrier has been routinely monitored between November 1994 and September 1998 as part of a Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) treatability test of barrier performance for the 200 BP 1 Operable Unit. Since FY 1998, monitoring has focused on a more limited set of key water balance, stability, and biotic parameters. In FY 2009, data collection was focused on: (1) water-balance monitoring, consisting of precipitation, runoff, soil moisture storage, and drainage measurements with evapotranspiration calculated by difference; (2) stability monitoring, consisting of asphalt-layer-settlement, basalt-side-slope-stability, and surface-elevation measurements; (3) vegetation dynamics; and (4) animal use. September 2009 marked 15 years since the start of monitoring and the collection of performance data. This report describes the results of monitoring activities during the period October 1, 2008, through September 30, 2009, and summarizes the 15 years of performance data collected from September 1994 through September 2009.

  10. Coronary artery occlusion after arterial switch operation in an asymptomatic 15-year-old boy.

    PubMed

    Saini, Ashish P; Cyran, Stephen E; Ettinger, Steven M; Pauliks, Linda B

    2016-08-16

    A 15-year-old boy with transposition of the great arteries (TGA) and neonatal arterial switch operation (ASO) presented with complete occlusion of the left main coronary artery (LMCA). Intra-operatively, an intramural left coronary artery was identified. Therefore, since age 7 years he had a series of screening exercise stress tests. At 13 years old, he had 3 to 4 mm ST segment depression in the infero-lateral leads without symptoms. This progressed to 4.2 mm inferior ST segment depression at 15 years old with normal stress echocardiogram. Sestamibi myocardial perfusion scan and cardiac magnetic resonance imaging was inconclusive. Therefore, a coronary angiogram was obtained which showed complete occlusion of the LMCA with ample collateralization from the right coronary artery system. This was later confirmed on a computed tomogram (CT) angiogram, obtained in preparation of coronary artery bypass grafting. The case illustrates the difficulty of detecting coronary artery stenosis and occlusion in young patients with rich collateralization. Coronary CT angiogram and conventional angiography were the best imaging modalities to detect coronary anomalies in this adolescent with surgically corrected TGA. Screening CT angiography may be warranted for TGA patients, particularly for those with known coronary anomalies.

  11. Coronary artery occlusion after arterial switch operation in an asymptomatic 15-year-old boy

    PubMed Central

    Saini, Ashish P; Cyran, Stephen E; Ettinger, Steven M; Pauliks, Linda B

    2016-01-01

    A 15-year-old boy with transposition of the great arteries (TGA) and neonatal arterial switch operation (ASO) presented with complete occlusion of the left main coronary artery (LMCA). Intra-operatively, an intramural left coronary artery was identified. Therefore, since age 7 years he had a series of screening exercise stress tests. At 13 years old, he had 3 to 4 mm ST segment depression in the infero-lateral leads without symptoms. This progressed to 4.2 mm inferior ST segment depression at 15 years old with normal stress echocardiogram. Sestamibi myocardial perfusion scan and cardiac magnetic resonance imaging was inconclusive. Therefore, a coronary angiogram was obtained which showed complete occlusion of the LMCA with ample collateralization from the right coronary artery system. This was later confirmed on a computed tomogram (CT) angiogram, obtained in preparation of coronary artery bypass grafting. The case illustrates the difficulty of detecting coronary artery stenosis and occlusion in young patients with rich collateralization. Coronary CT angiogram and conventional angiography were the best imaging modalities to detect coronary anomalies in this adolescent with surgically corrected TGA. Screening CT angiography may be warranted for TGA patients, particularly for those with known coronary anomalies. PMID:27574609

  12. Coronary artery occlusion after arterial switch operation in an asymptomatic 15-year-old boy.

    PubMed

    Saini, Ashish P; Cyran, Stephen E; Ettinger, Steven M; Pauliks, Linda B

    2016-08-16

    A 15-year-old boy with transposition of the great arteries (TGA) and neonatal arterial switch operation (ASO) presented with complete occlusion of the left main coronary artery (LMCA). Intra-operatively, an intramural left coronary artery was identified. Therefore, since age 7 years he had a series of screening exercise stress tests. At 13 years old, he had 3 to 4 mm ST segment depression in the infero-lateral leads without symptoms. This progressed to 4.2 mm inferior ST segment depression at 15 years old with normal stress echocardiogram. Sestamibi myocardial perfusion scan and cardiac magnetic resonance imaging was inconclusive. Therefore, a coronary angiogram was obtained which showed complete occlusion of the LMCA with ample collateralization from the right coronary artery system. This was later confirmed on a computed tomogram (CT) angiogram, obtained in preparation of coronary artery bypass grafting. The case illustrates the difficulty of detecting coronary artery stenosis and occlusion in young patients with rich collateralization. Coronary CT angiogram and conventional angiography were the best imaging modalities to detect coronary anomalies in this adolescent with surgically corrected TGA. Screening CT angiography may be warranted for TGA patients, particularly for those with known coronary anomalies. PMID:27574609

  13. Nonfatal bathroom injuries among persons aged ≥15 years--United States, 2008.

    PubMed

    2011-06-10

    In 2008, approximately 21.8 million persons aged ≥15 years sustained nonfatal, unintentional injuries, resulting in approximately $67.3 billion in lifetime medical costs. Information about where injuries occur is limited, but bathrooms commonly are believed to be a particularly hazardous location. To investigate this assumption, CDC analyzed data from a nationally representative sample of emergency departments (EDs) to describe the incidence and circumstances of nonfatal injuries in bathrooms (in any setting) among persons aged ≥15 years in the United States. This report describes the results of that investigation, which found that, based on 3,339 cases documented in the 2008 National Electronic Surveillance System All Injury Program (NEISS-AIP) database, an estimated 234,094 nonfatal bathroom injuries were treated in U.S. EDs. Injury rates increased with age, and most injuries (81.1%) were caused by falls. All persons, but especially older adults, should be aware of bathroom activities that are associated with a high risk for injury and of environmental modifications that might reduce that risk. PMID:21659980

  14. [Radiology of osteoarticular changes in patients undergoing periodic hemodialysis for more than 15 years].

    PubMed

    Orzincolo, C; Bedani, P L; Scutellari, P N; Ghedini, M; Storari, A; Cavallari, L; Cardona, P

    1991-05-01

    Osteoarticular complications, which are characterized by osseous pain, pathologic fractures, and decreased articular mobility, represent one of the major problems affecting long-term (over 15 years) hemodialysis patients. These changes seem to have a multifactorial etiology; they include osteomalacia, secondary hyperparathyroidism, and dialysis-related amyloidosis. Ten patients (5 males and 5 females, mean age 55 +/- 7 years) on long-term (over 15 years) hemodialysis were submitted to X-ray examinations of the skull, spine, shoulders, wrists, pelvis, and knees. Serum calcium, phosphorous, parathyroid hormone, alkaline phosphatase, and basal aluminium levels were also calculated. Osteopenia was demonstrated in all patients. Seven of them had alterations due to hyperparathyroidism. Six patients exhibited signs related to dialysis spondyloarthropathy; in 9 cases amyloid lesions, geodes, and erosions were present in wrists, humeral heads, or hips. One patient exhibited osteomalacic changes. Most long-term dialysis patients presented multifactorial osteoarticular changes due to hyperparathyroidism, osteomalacia, and dialysis-related amyloidosis. Clinical symptoms and decreased articular mobility appeared to be due mainly to amyloid osteoarthropathy.

  15. [Statistical studies on suicides in Shiga Prefecture during the 15-year period, 1974 to 1988].

    PubMed

    Yamamoto, Y; Yamada, M; Fukunaga, T; Tatsuno, Y

    1990-04-01

    The authors examined 3,335 cases of suicides among the unnatural deaths in Shiga Prefecture during the 15-year period, 1974 to 1988. The results obtained were as follows: The number of suicides in a year amounted to 200 during the period from 1974 to 1982, and increased to 280 in 1983 at maximum. The cases of suicide were more in male than in female. The incidence of suicide was higher in March to July and the peak of incidence was observed in April. The highest frequency of suicides was in 40-49 year age group in male, and 70-79 year group in female. Among various procedures of suicide, hanging was most frequent during the past 15 years in both sexes, and the following procedure was carbon monoxide poisoning in male and drowning in female. As to the occupation, housewives and person without a regular occupation constituted 53.1% of the total suicidal cases, and products makers and laborers were found in 11.1%. With regarded to the causative factors, "suffering from illness" was the most frequent factor, and followed by "insanity or mental disorder", "problems of economic distress", "disagreement with family" and others.

  16. Pulse Pressure Magnifies the Effect of COMT Val(158)Met on 15 Years Episodic Memory Trajectories.

    PubMed

    Persson, Ninni; Lavebratt, Catharina; Sundström, Anna; Fischer, Håkan

    2016-01-01

    We investigated whether a physiological marker of cardiovascular health, pulse pressure (PP), and age magnified the effect of the functional COMT Val(158)Met (rs4680) polymorphism on 15-years cognitive trajectories [episodic memory (EM), visuospatial ability, and semantic memory] using data from 1585 non-demented adults from the Betula study. A multiple-group latent growth curve model was specified to gauge individual differences in change, and average trends therein. The allelic variants showed negligible differences across the cognitive markers in average trends. The older portion of the sample selectively age-magnified the effects of Val(158)Met on EM changes, resulting in greater decline in Val compared to homozygote Met carriers. This effect was attenuated by statistical control for PP. Further, PP moderated the effects of COMT on 15-years EM trajectories, resulting in greater decline in Val carriers, even after accounting for the confounding effects of sex, education, cardiovascular diseases (diabetes, stroke, and hypertension), and chronological age, controlled for practice gains. The effect was still present after excluding individuals with a history of cardiovascular diseases. The effects of cognitive change were not moderated by any other covariates. This report underscores the importance of addressing synergistic effects in normal cognitive aging, as the addition thereof may place healthy individuals at greater risk for memory decline. PMID:26973509

  17. Reproducibility of a web-based FFQ for 13- to 15-year-old Danish adolescents.

    PubMed

    Bjerregaard, Anne A; Tetens, Inge; Olsen, Sjurdur F; Halldorsson, Thorhallur I

    2016-01-01

    FFQ are widely used in large-scale studies to assess dietary intake. To aid interpretation of diet-disease associations assessment of validity must be performed. Reproducibility is one aspect of validity focusing on the stability of repeated assessment with the same method which may also reveal problems in instrument design or participant instructions. The aim of the present study was to evaluate the reproducibility of a web-based FFQ targeting Danish adolescents within the Danish National Birth Cohort (DNBC). Data for the present study were obtained from a prospective design nested within the DNBC. Adolescents aged 13 to 15 years old (n 48, 60 % girls) completed the FFQ twice 4 weeks apart. The proportion of adolescents consistently classified into the same tertile according to amount of food intake ranged from 45 % (fish) to 77 % (vegetables), whereas classification into opposite tertiles ranged from 0 % (fruit, oils and dressing) to 15 % (beverages). Overall, no significant differences were observed in intake of food groups or nutrients between the two completions of the FFQ. Mean crude Spearman correlation for all food groups was 0·56 and mean intra-class correlation for all food groups was 0·61. In conclusion, the reproducibility of the FFQ for Danish adolescents was acceptable. The study revealed that adolescents aged 13-15 years seemed capable of recalling consistently overall dietary habits and had some difficulties estimating the frequency of consumption of regularly consumed food items. PMID:26855775

  18. High aerosol acidity despite declining atmospheric sulfate concentrations over the past 15 years

    NASA Astrophysics Data System (ADS)

    Weber, Rodney J.; Guo, Hongyu; Russell, Armistead G.; Nenes, Athanasios

    2016-04-01

    Particle acidity affects aerosol concentrations, chemical composition and toxicity. Sulfate is often the main acid component of aerosols, and largely determines the acidity of fine particles under 2.5 μm in diameter, PM2.5. Over the past 15 years, atmospheric sulfate concentrations in the southeastern United States have decreased by 70%, whereas ammonia concentrations have been steady. Similar trends are occurring in many regions globally. Aerosol ammonium nitrate concentrations were assumed to increase to compensate for decreasing sulfate, which would result from increasing neutrality. Here we use observed gas and aerosol composition, humidity, and temperature data collected at a rural southeastern US site in June and July 2013 (ref. ), and a thermodynamic model that predicts pH and the gas-particle equilibrium concentrations of inorganic species from the observations to show that PM2.5 at the site is acidic. pH buffering by partitioning of ammonia between the gas and particle phases produced a relatively constant particle pH of 0-2 throughout the 15 years of decreasing atmospheric sulfate concentrations, and little change in particle ammonium nitrate concentrations. We conclude that the reductions in aerosol acidity widely anticipated from sulfur reductions, and expected acidity-related health and climate benefits, are unlikely to occur until atmospheric sulfate concentrations reach near pre-anthropogenic levels.

  19. Effect of frame size and time-on-pasture on steer performance, longissimus muscle fatty acid composition, and tenderness in a forage-finishing system.

    PubMed

    Duckett, S K; Fernandez Rosso, C; Volpi Lagreca, G; Miller, M C; Neel, J P S; Lewis, R M; Swecker, W S; Fontenot, J P

    2014-10-01

    Angus-cross steers (n = 96; BW = 309 ± 34 kg; 13.5 mo of age) were used to determine the effects of frame size (medium or small) and time-on-pasture (TOP) on meat composition and palatability in a 2-yr study. Finishing steers grazed mixed pastures (bluegrass/white clover; April start) and were slaughtered after 89-, 146-, and 201-d TOP. At 24 h postmortem, carcass traits were collected and a rib from each carcass was obtained for proximate and fatty acid composition, Warner-Bratzler shear force (WBSF), and postmortem proteolysis. In yr 1, postmortem aging treatments included 14 and 28 d, whereas in yr 2, postmortem aging treatments included 2, 4, 7, 14, and 28 d. Increasing frame size of the finishing steers produced greater (P < 0.05) ADG by 0.10 kg, BW by 24 kg, HCW by 14 kg, and ribeye size by 2.65 cm(2). All other carcass, meat composition, and tenderness measures did not differ (P > 0.05) due to frame size or 2-way interaction with TOP. Increasing TOP resulted in quadratic increases (P < 0.01) in BW and HCW. Ribeye area, fat thickness, KPH, marbling scores, quality grades, and yield grades increased (P < 0.001) linearly as TOP increased. Time-on-pasture linearly increased (P = 0.001) palmitic (C16:0) acid, oleic (C18:1 cis-9) acid, SFA, and MUFA in the LM. Both n-6 PUFA, linoleic (C18:2) and arachidonic (C20:4) acids, decreased linearly (P = 0.001) with increasing TOP. Increasing TOP linearly reduced (P = 0.01) concentrations of all n-3 fatty acids in the LM. These changes resulted in a linear reduction (P = 0.01) in n-6 to n-3 fatty acid ratio with advancing TOP; however, the magnitude of the difference was small (1.46 vs. 1.37). At 14 d of postmortem aging, WBSF was lowest (P < 0.001) for 89-d TOP and greatest (P < 0.05) for the 201-d TOP. After 28 d of postmortem aging, WBSF values for 89- and 146-d TOP did not differ (P > 0.05) compared to the 14-d postmortem aging WBSF values. However, in steaks from 201-d TOP, additional postmortem aging to 28 d reduced

  20. Solar/hydrogen systems assessment. Volume 1: Solar/hydrogen systems for the 1985 - 2000 time frame

    NASA Technical Reports Server (NTRS)

    Foster, R. W.; Tison, R. R.; Escher, W. J. D.; Hanson, J. A.

    1980-01-01

    Opportunities for commercialization of systems capable of producing hydrogen from solar energy were studied. The hydrogen product costs that might be achieved by the four selected candidate systems was compared with the pricing structure and practices of the commodity gas market. Subsequently, product cost and market price match was noted to exist in the small user sector of the hydrogen marketplace. Barriers to and historical time lags in, commercialization of new technologies are reviewed. Recommendations for development and demonstration programs designed to accelerate the commercialization of the candidate systems are presented.

  1. Cardiorespiratory Fitness Levels among U.S. Youth Aged 12-15 Years: United States, 1999-2004 and 2012

    MedlinePlus

    ... the National Technical Information Service NCHS Cardiorespiratory Fitness Levels Among U.S. Youth Aged 12–15 Years: United ... of girls aged 12–15 years had adequate levels of cardiorespiratory fitness. Overall, 42.2% of youth ...

  2. 29 CFR 570.31 - Secretary's determinations concerning the employment of minors 14 and 15 years of age.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... minors 14 and 15 years of age. 570.31 Section 570.31 Labor Regulations Relating to Labor (Continued) WAGE... INTERPRETATION Employment of Minors Between 14 and 16 Years of Age (Child Labor Reg. 3) § 570.31 Secretary's determinations concerning the employment of minors 14 and 15 years of age. The employment of minors between...

  3. 29 CFR 570.31 - Secretary's determinations concerning the employment of minors 14 and 15 years of age.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... minors 14 and 15 years of age. 570.31 Section 570.31 Labor Regulations Relating to Labor (Continued) WAGE... INTERPRETATION Employment of Minors Between 14 and 16 Years of Age (Child Labor Reg. 3) § 570.31 Secretary's determinations concerning the employment of minors 14 and 15 years of age. The employment of minors between...

  4. 29 CFR 570.31 - Secretary's determinations concerning the employment of minors 14 and 15 years of age.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... minors 14 and 15 years of age. 570.31 Section 570.31 Labor Regulations Relating to Labor (Continued) WAGE... INTERPRETATION Employment of Minors Between 14 and 16 Years of Age (Child Labor Reg. 3) § 570.31 Secretary's determinations concerning the employment of minors 14 and 15 years of age. The employment of minors between...

  5. 29 CFR 570.31 - Secretary's determinations concerning the employment of minors 14 and 15 years of age.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... minors 14 and 15 years of age. 570.31 Section 570.31 Labor Regulations Relating to Labor (Continued) WAGE... INTERPRETATION Employment of Minors Between 14 and 16 Years of Age (Child Labor Reg. 3) § 570.31 Secretary's determinations concerning the employment of minors 14 and 15 years of age. The employment of minors between...

  6. Multi-Directional Sprinting and Acceleration Phase in Basketball and Handball Players Aged 14 and 15 Years.

    PubMed

    Popowczak, Marek; Rokita, Andrzej; Struzik, Artur; Cichy, Ireneusz; Dudkowski, Andrzej; Chmura, Paweł

    2016-10-01

    An important role in handball and basketball is played by ability to accelerate and ability to repeat multiple sprints. The aim of the study was to assess level of ability in multi-directional sprinting and running time over the first 5 m of the 30 m sprint in 93 basketball and handball players (46 boys and 47 girls) aged 14 to 15 years. The attempts were also made to find the relationships between the time of a 5-m run to evaluate initial acceleration phase and multi-directional sprinting evaluated using Five-Time Shuttle Run To Gates Test Statistical analysis revealed no important differences in times of 5-m runs and times of multi-directional sprinting between groups with different ages, genders, and sports specialties. Furthermore, no significant correlations were found based on Spearman's rank correlation coefficient between times of 5-m run and multi-directional sprinting in the most of subgroups studied. PMID:27565172

  7. Ten- to 15-year results of the Oxford Phase III mobile unicompartmental knee arthroplasty

    PubMed Central

    Lisowski, L. A.; Meijer, L. I.; van den Bekerom, M. P. J.; Pilot, P.; Lisowski, A. E.

    2016-01-01

    Aims The interest in unicompartmental knee arthroplasty (UKA) for medial osteoarthritis has increased rapidly but the long-term follow-up of the Oxford UKAs has yet to be analysed in non-designer centres. We have examined our ten- to 15-year clinical and radiological follow-up data for the Oxford Phase III UKAs. Patients and Methods Between January 1999 and January 2005 a total of 138 consecutive Oxford Phase III arthroplasties were performed by a single surgeon in 129 patients for medial compartment osteoarthritis (71 right and 67 left knees, mean age 72.0 years (47 to 91), mean body mass index 28.2 (20.7 to 52.2)). Both clinical data and radiographs were prospectively recorded and obtained at intervals. Of the 129 patients, 32 patients (32 knees) died, ten patients (12 knees) were not able to take part in the final clinical and radiological assessment due to physical and mental conditions, but via telephone interview it was confirmed that none of these ten patients (12 knees) had a revision of the knee arthroplasty. One patient (two knees) was lost to follow-up. Results The mean follow-up was 11.7 years (10 to 15). A total of 11 knees (8%) were revised. The survival at 15 years with revision for any reason as the endpoint was 90.6% (95% confidence interval (CI) 85.2 to 96.0) and revision related to the prosthesis was 99.3% (95% CI 97.9 to 100). The mean total Knee Society Score was 47 (0 to 80) pre-operatively and 81 (30 to 100) at latest follow-up. The mean Oxford Knee Score was 19 (12 to 40) pre-operatively and 42 (28 to 55) at final follow-up. Radiolucency beneath the tibial component occurred in 22 of 81 prostheses (27.2%) without evidence of loosening. Conclusion This study supports the use of UKA in medial compartment osteoarthritis with excellent long-term functional and radiological outcomes with an excellent 15-year survival rate. Cite this article: Bone Joint J 2016;98-B(10 Suppl B):41–7. PMID:27694515

  8. The time-frame of acute resistance exercise effects on football skill performance: the impact of exercise intensity.

    PubMed

    Draganidis, Dimitrios; Chatzinikolaou, Athanasios; Jamurtas, Athanasios Z; Carlos Barbero, Jose; Tsoukas, Dimitrios; Theodorou, Apostolos Spyridon; Margonis, Konstantinos; Michailidis, Yannis; Avloniti, Alexandra; Theodorou, Anastasios; Kambas, Antonis; Fatouros, Ioannis

    2013-01-01

    The purpose of this study was to determine the recovery rate of football skill performance following resistance exercise of moderate or high intensity. Ten elite football players participated in three different trials: control, low-intensity resistance exercise (4 sets, 8-10 repetitions/set, 65-70% 1 repetition maximum [1RM]) and high-intensity resistance exercise (4 sets, 4-6 repetitions/set, 85-90% 1RM) in a counterbalanced manner. In each experimental condition, participants were evaluated pre, post, and at 24, 48, 72 h post exercise time points. Football skill performance was assessed through the Loughborough Soccer Passing Test, long passing, dribbling, shooting and heading. Delayed onset muscle soreness, knee joint range of motion, and muscle strength (1RM) in squat were considered as muscle damage markers. Blood samples analysed for creatine kinase activity, C-reactive protein, and leukocyte count. Passing and shooting performance declined (P < 0.05) post-exercise following resistance exercise. Strength declined post-exercise following high-intensity resistance exercise. Both trials induced only a mild muscle damage and inflammatory response in an intensity-dependent manner. These results indicate that football skill performance is minimally affected by acute resistance exercise independent of intensity suggesting that elite players may be able to participate in a football practice or match after only 24 h following a strength training session. PMID:23301779

  9. The time-frame of acute resistance exercise effects on football skill performance: the impact of exercise intensity.

    PubMed

    Draganidis, Dimitrios; Chatzinikolaou, Athanasios; Jamurtas, Athanasios Z; Carlos Barbero, Jose; Tsoukas, Dimitrios; Theodorou, Apostolos Spyridon; Margonis, Konstantinos; Michailidis, Yannis; Avloniti, Alexandra; Theodorou, Anastasios; Kambas, Antonis; Fatouros, Ioannis

    2013-01-01

    The purpose of this study was to determine the recovery rate of football skill performance following resistance exercise of moderate or high intensity. Ten elite football players participated in three different trials: control, low-intensity resistance exercise (4 sets, 8-10 repetitions/set, 65-70% 1 repetition maximum [1RM]) and high-intensity resistance exercise (4 sets, 4-6 repetitions/set, 85-90% 1RM) in a counterbalanced manner. In each experimental condition, participants were evaluated pre, post, and at 24, 48, 72 h post exercise time points. Football skill performance was assessed through the Loughborough Soccer Passing Test, long passing, dribbling, shooting and heading. Delayed onset muscle soreness, knee joint range of motion, and muscle strength (1RM) in squat were considered as muscle damage markers. Blood samples analysed for creatine kinase activity, C-reactive protein, and leukocyte count. Passing and shooting performance declined (P < 0.05) post-exercise following resistance exercise. Strength declined post-exercise following high-intensity resistance exercise. Both trials induced only a mild muscle damage and inflammatory response in an intensity-dependent manner. These results indicate that football skill performance is minimally affected by acute resistance exercise independent of intensity suggesting that elite players may be able to participate in a football practice or match after only 24 h following a strength training session.

  10. Solar/hydrogen systems for the 1985 to 2000 time frame. Volume I. Solar/hydrogen systems assessment. Final report

    SciTech Connect

    Foster, R. W.; Tison, R. R.; Escher, W. J.D.; Hanson, J. A.

    1980-06-01

    The findings of a study of opportunities for commercialization of systems capable of producing hydrogen from solar energy are presented in two volumes. A compendium of monographs by specialists in the fields of solar energy conversion technologies, hydrogen production technologies and related technology descriptions from the general literature comprise Volume II. This data base was used to support an evaluation and selection process that identified four candidate solar/hydrogen systems best suited to commercialization within the next two decades. Volume I first reviews the background of the work and the methods used. Then an evaluation of the hydrogen product costs that might be achieved by the four selected candidate systems (photovoltaic/water electrolysis, thermal-heat engine/water electrolysis, wind energy/water electrolysis, small hydrogen/water electrolysis) is compared with the pricing structure and practices of the commodity gas market. Subsequently, product cost and market price match is noted to exist in the small user sector of the hydrogen marketplace. Barriers to and historical time lags in, commercialization of new technologies are then reviewed. Finally, recommendations for development and demonstration programs designed to accelerate the commercialization of the candidate systems are presented.

  11. Real-time cardiac synchronization with fixed volume frame rate for reducing physiological instabilities in 3D FMRI.

    PubMed

    Tijssen, Rob H N; Okell, Thomas W; Miller, Karla L

    2011-08-15

    Although 2D echo-planar imaging (EPI) remains the dominant method for functional MRI (FMRI), 3D readouts are receiving more interest as these sequences have favorable signal-to-noise ratio (SNR) and enable imaging at a high isotropic resolution. Spoiled gradient-echo (SPGR) and balanced steady-state free-precession (bSSFP) are rapid sequences that are typically acquired with highly segmented 3D readouts, and thus less sensitive to image distortion and signal dropout. They therefore provide a powerful alternative for FMRI in areas with strong susceptibility offsets, such as deep gray matter structures and the brainstem. Unfortunately, the multi-shot nature of the readout makes these sequences highly sensitive to physiological fluctuations, and large signal instabilities are observed in the inferior regions of the brain. In this work a characterization of the source of these instabilities is given and a new method is presented to reduce the instabilities observed in 3D SPGR and bSSFP. Rapidly acquired single-slice data, which critically sampled the respiratory and cardiac waveforms, showed that cardiac pulsation is the dominant source of the instabilities. Simulations further showed that synchronizing the readout to the cardiac cycle minimizes the instabilities considerably. A real-time synchronization method was therefore developed, which utilizes parallel-imaging techniques to allow cardiac synchronization without alteration of the volume acquisition rate. The implemented method significantly improves the temporal stability in areas that are affected by cardiac-related signal fluctuations. In bSSFP data the tSNR in the brainstem increased by 45%, at the cost of a small reduction in tSNR in the cortical areas. In SPGR the temporal stability is improved by approximately 20% in the subcortical structures and as well as cortical gray matter when synchronization was performed.

  12. Green-laser induced maculopathy in a 15-year-old boy.

    PubMed

    Yan, William; Chakrabarti, Rahul; Little, Matthew; Carden, Susan M

    2016-06-01

    We report the case a 15-year-old boy who presented with retinopathy caused by a green-diode (class IIIB) laser. The patient was followed over a period of 8 weeks. Visual acuity on day 1 was 6/7.5, with central scotoma in the right eye, and 6/5 in the left eye. Macular optical coherence tomography of the right eye day 1 showed focal subfoveal disruption of the photoreceptor ellipsoid and myoid zones extending through the external limiting membrane to the outer nuclear layer. At week 8, visual acuity was 6/6 right eye and 6/5 in the left eye. Disruption of the ellipsoid and myoid layers, though still present, had improved.

  13. Mosquito Surveillance for 15 Years Reveals High Genetic Diversity Among West Nile Viruses in Israel.

    PubMed

    Lustig, Yaniv; Hindiyeh, Musa; Orshan, Laor; Weiss, Leah; Koren, Ravit; Katz-Likvornik, Shiri; Zadka, Hila; Glatman-Freedman, Aharona; Mendelson, Ella; Shulman, Lester M

    2016-04-01

    West Nile Virus (WNV) is endemic in Israel and has been the cause of several outbreaks in recent years. In 2000, a countrywide mosquito survey was established to monitor WNV activity and characterize viral genotypes in Israel. We analyzed data from 7135 pools containing 277 186 mosquitoes collected over the past 15 years and, here, report partial sequences of WNV genomes obtained from 102 of the 336 positive mosquito pools. Phylogenetic analysis demonstrated that cluster 4 and the Mediterranean and Eastern European subtypes of cluster 2 within WNV lineage 1 circulated in Israel, as did WNV lineage 2, highlighting a high genetic diversity of WNV genotypes in our region. As a major crossroads for bird migration between Africa and Eurasia and with a long history of human infection, Israel serves as a resource hub for WNV in Africa and Eurasia and provides valuable information on WNV circulation in these regions. PMID:26597260

  14. 15-Year blast furnace campaign concept for the reline of blast furnace C at Iscor

    SciTech Connect

    Noska, T.G.L.

    1995-07-01

    Since the 1970`s, when blast furnace campaigns of 3 to 5 years were experienced at the Vanderbijlpark Works, consequent improvements of cooling and refractory concepts as well as the development of a hot guniting practice for belly and lower shaft resulted in campaigns of 10 years and more. Having mastered the problems in belly and lower shaft, the furnace hearth became the ultimate limit and two hearth breakouts were experienced in the last 5 years in South Africa. After analyzing the causes for these breakouts, the requirements for a hearth refractory design, aimed at a 15-year plus campaign life, were formulated. A refractory design concept, which satisfies these requirements were developed based on European, American and Japanese philosophies.

  15. Patch-test results in children and adolescents: systematic review of a 15-year period*

    PubMed Central

    Rodrigues, Dulcilea Ferraz; Goulart, Eugênio Marcos Andrade

    2016-01-01

    The number of studies on patch-test results in children and adolescents has gradually increased in recent years, thus stimulating reviews. This paper is a systematic review of a 15-year period devoted to studying the issue. Variations pertaining to the number and age groups of tested children and/or adolescents, the number of subjects with atopy/atopic dermatitis history, the quantity, type and concentrations of the tested substances, the test technique and type of data regarding clinical relevance, must all be considered in evaluating these studies, as they make it harder to formulate conclusions. The most common allergens in children were nickel, thimerosal, cobalt, fragrance, lanolin and neomycin. In adolescents, they were nickel, thimerosal, cobalt, fragrance, potassium dichromate, and Myroxylon pereirae. Knowledge of this matter aids health professionals in planning preventive programs aimed at improving children's quality of life and ensuring that their future prospects are not undermined. PMID:26982781

  16. Laparoscopic surgery: surgical education in the People's Republic of China: changes after 15 years.

    PubMed

    Li, Ji-Hui; Witzke, Donald B; Gagliardi, Raymond J

    2007-06-01

    The introduction of laparoscopic surgery education in Mainland China took place in 1991, when Chinese surgeons rushed to the hospital where the first laparoscopic cholecystectomy in the country was performed to learn the keyhole technique; and different groups of surgeons from Western countries visited the land to convey their experience and foresight with their friendship. The situation in laparoscopic surgery and its education has changed a lot in the last 15 years. Communication via conference and workshops are used heavily as a teaching method in laparoscopic surgery education. Technical training is conveyed mainly in laparoscopic centers. Simple simulators created by Chinese surgeons, technical support by the Western forerunners, financial support, and other resources from major companies, and the large population contributed a lot to the fast development of laparoscopic surgery in China. PMID:17581456

  17. Targeted sustainable development: 15 years of government and community intervention on the St. Lawrence River.

    PubMed

    Villeneuve, Serge; Painchaud, Jean; Dugas, Clément

    2006-02-01

    From 1988 to 2003, the St. Lawrence Action Plan, a Canada - Quebec cooperation agreement on the St. Lawrence River, helped to mobilize a still-growing number of stakeholders in the conservation and protection of this great river and generated tangible results in a number of areas of intervention. The successes enjoyed in the area of industrial, agricultural and urban clean-up, in protecting plant and animal species and their habitats, and in acquiring new knowledge on the state and trends of the ecosystem reflect the sustained efforts of government and non-government partners over the course of those 15 years. The committed involvement of local communities provides assurance of the sustainable development of this vast ecosystem.

  18. Pelvic osteomyelitis in a 15-year-old girl: case report.

    PubMed

    Tural Kara, Tugce; Ozdemir, Halil; Fitoz, Suat; Ciftci, Ergin; Ince, Erdal

    2016-10-01

    Pelvic osteomyelitis is a rare infection. Ilium, ischium, pubis and acetabulum are commonly affected sites. Pelvic radiography, pelvic magnetic resonance and scintigraphy are useful imaging techniques for diagnosis. However, diagnoses should be confirmed with bone biopsy from the lesion. Sometimes diagnosis is delayed because of deep localization of infection site. Here in, we report a 15-year-old girl with left groin pain who was diagnosed as pelvic osteomyelitis one month after initial symptoms. Patient was successfully treated with antibiotics for 8 weeks. In conclusion, although pelvic osteomyelitis is an unusual infection in childhood, it should be considered as differential diagnoses of pain in groin, hips, thigh, abdomen and spine. If diagnosis is suspicious, empiric treatment should be started quickly, because it will be possible to achieve satisfactory clinical results with effective treatment. PMID:27606666

  19. Isolated 3-methylcrotonyl-CoA carboxylase deficiency in a 15-year-old girl.

    PubMed

    Murayama, K; Kimura, M; Yamaguchi, S; Shinka, T; Kodama, K

    1997-06-01

    A 15-year-old girl with a former clinical diagnosis of cerebral palsy was found to have isolated deficiency of 3-methylcrotonyl-CoA carboxylase (MCC) on gas chromatography-mass spectrometry (GC/MS) analysis and enzyme determination. Her symptoms included marked growth retardation from birth, profound mental retardation, tonic seizures, rigospastic quadriplegia with opisthotonic dystonia, gastroesophageal reflux with poor esophageal peristalsis, and recurrent episodes of aspiration pneumonia. Brain MRI revealed marked brain atrophy, involving both the gray and white matter. Although she did not exhibit acute metabolic decompensation or acute encephalopathy, her neurological symptoms continuously worsened. This patient is the oldest among reported cases of MCC deficiency who had symptoms at birth, and this case may have the severest sequelae of the longest known natural course of this inborn error of metabolism.

  20. Once Annealed Highly Cross-Linked Polyethylene Exhibits Low Wear at 9 to 15 Years.

    PubMed

    D'Antonio, James; Capello, William N; Ramakrishnan, Rama

    2016-05-01

    A once annealed highly cross-linked polyethylene (HXLPE) was introduced in 1998. Concerns regarding its long-term performance and oxidative resistance exist because of the presence of retained free radicals. The authors studied 48 patients with 50 hip implants having an average age of 62 years. They were followed for 9 to 15 years. The purpose of this study was to determine linear wear rate and the incidence of osteolysis and/or mechanical failure. At an average follow-up of 12.2 years, the annual linear wear rate was 0.018 mm (SD, 0.024 mm). No mechanical failures or osteolysis have been found to date. The clinical performance of this HXLPE continues to meet expectations despite the presence of free radicals. [Orthopedics. 2016; 39(3):e565-e571.]. PMID:27088350

  1. The endovascular management of recurrent aortic hypoplasia and coarctation in a 15-year-old male.

    PubMed

    Rhodes, Andrew B; O'Donnell, Sean D; Gillespie, David L; Rasmussen, Todd E; Johnson, Chatt A; Fox, Charles J; Burklow, Thomas R; Hagler, David J

    2005-03-01

    A 15-year-old male complained of easy fatigability, leg weakness, and pain on exertion with episodes of syncope while playing baseball. His past medical history was significant for aortic coarctation associated with a congenital bovine hypoplastic aortic arch. A recent arteriogram revealed innominate and left common carotid artery stenosis as well as recurrent coarctation. He had previously undergone three Dacron patch aortoplasties. At the age of 7, he underwent a fourth operation for recurrent coarctation and because of extensive scar tissue in the region of his prior procedures, a left subclavian artery-to-descending aortic bypass was performed. An endovascular repair to deal with the recent recurrence was performed because of prior surgical difficulties. Percutaneous balloon-expandable stents were placed in the aortic coarctation, innominate, and the left common carotid arteries. Postprocedure, ankle brachial indices were >1 and the patient remains asymptomatic after 1 year.

  2. Pelvic osteomyelitis in a 15-year-old girl: case report.

    PubMed

    Tural Kara, Tugce; Ozdemir, Halil; Fitoz, Suat; Ciftci, Ergin; Ince, Erdal

    2016-10-01

    Pelvic osteomyelitis is a rare infection. Ilium, ischium, pubis and acetabulum are commonly affected sites. Pelvic radiography, pelvic magnetic resonance and scintigraphy are useful imaging techniques for diagnosis. However, diagnoses should be confirmed with bone biopsy from the lesion. Sometimes diagnosis is delayed because of deep localization of infection site. Here in, we report a 15-year-old girl with left groin pain who was diagnosed as pelvic osteomyelitis one month after initial symptoms. Patient was successfully treated with antibiotics for 8 weeks. In conclusion, although pelvic osteomyelitis is an unusual infection in childhood, it should be considered as differential diagnoses of pain in groin, hips, thigh, abdomen and spine. If diagnosis is suspicious, empiric treatment should be started quickly, because it will be possible to achieve satisfactory clinical results with effective treatment.

  3. X-ray emission from interacting wind massive binaries: A review of 15 years of progress

    NASA Astrophysics Data System (ADS)

    Rauw, Gregor; Nazé, Yaël

    2016-09-01

    Previous generations of X-ray observatories revealed a group of massive binaries that were relatively bright X-ray emitters. This was attributed to emission of shock-heated plasma in the wind-wind interaction zone located between the stars. With the advent of the current generation of X-ray observatories, the phenomenon could be studied in much more detail. In this review, we highlight the progress that has been achieved in our understanding of the phenomenon over the last 15 years, both on theoretical and observational grounds. All these studies have paved the way for future investigations using the next generation of X-ray satellites that will provide crucial information on the X-ray emission formed in the innermost part of the wind-wind interaction.

  4. Patch-test results in children and adolescents: systematic review of a 15-year period.

    PubMed

    Rodrigues, Dulcilea Ferraz; Goulart, Eugênio Marcos Andrade

    2016-01-01

    The number of studies on patch-test results in children and adolescents has gradually increased in recent years, thus stimulating reviews. This paper is a systematic review of a 15-year period devoted to studying the issue. Variations pertaining to the number and age groups of tested children and/or adolescents, the number of subjects with atopy/atopic dermatitis history, the quantity, type and concentrations of the tested substances, the test technique and type of data regarding clinical relevance, must all be considered in evaluating these studies, as they make it harder to formulate conclusions. The most common allergens in children were nickel, thimerosal, cobalt, fragrance, lanolin and neomycin. In adolescents, they were nickel, thimerosal, cobalt, fragrance, potassium dichromate, and Myroxylon pereirae. Knowledge of this matter aids health professionals in planning preventive programs aimed at improving children's quality of life and ensuring that their future prospects are not undermined.

  5. Results of our 15-year study into the biological effects of microwave exposure.

    PubMed

    Djordjević, Z; Kolak, A; Djoković, V; Ristić, P; Kelećević, Z

    1983-06-01

    The results obtained during 15 years of clinical and experimental examinations of biological microwave exposure effects are briefly surveyed. Some important results are reported. Based on their experience, the authors present their attitudes concerning harmful microwave effects on living matter. They consider that microwave effects, either direct or indirect, are the results of hyperthermia. Exposure of the living body to irradiation intensities not causing thermal effects do not induce important pathological alterations in the irradiated organisms. Also, it has been pointed out that the term "injury" is more suitable than the term "microwave sickness" when harmful effects of microwaves to the living organism are concerned. According to the authors, the term "microwave sickness" is not acceptable as a synonym for professional diseases of persons working with sources of microwave energy, since it refers to the complex of insufficiently defined symptoms of uncertain etiology. PMID:6882314

  6. Prevalence of Waterpipe Tobacco Smoking Among Population Aged 15 Years or Older, Vietnam, 2010

    PubMed Central

    Van Minh, Hoang; Giang, Kim Bao; Nga, Pham Thi Quynh; Hai, Phan Thi; Minh, Nguyen Thac; Hsia, Jason

    2013-01-01

    Introduction The prevalence of waterpipe tobacco smoking is increasing globally and is associated with adverse outcomes requiring tobacco control interventions. We estimated the prevalence of waterpipe tobacco use among adult populations in Vietnam in 2010 and examined its association with sociodemographic factors. Methods We used data from the Global Adult Tobacco Survey (GATS) conducted in Vietnam in 2010. GATS surveyed a national representative sample of adults aged 15 years or older from 11,142 households by using a 2-phase sampling design analogous to a 3-stage stratified cluster sampling. Descriptive statistical analyses and multivariate logistic regression modeling were conducted. Results A total of 6.4% of Vietnamese aged 15 years or older (representing about 4.1 million adult waterpipe smokers) reported current waterpipe tobacco smoking. The prevalence of waterpipe tobacco smoking was significantly higher among men than women (13% vs 0.1%). Area of residence (rural or urban), age group, asset-based wealth quintile, and geographic region of residence were significantly associated with waterpipe tobacco smoking among men. The significant correlates of current waterpipe tobacco smoking among men were lower education levels, being middle-aged (45–54 years), lower asset-based wealth levels, living in rural areas, not living in the South East and the Mekong River Delta geographic regions, and the belief that smoking does not causes diseases. Conclusion Rural dwellers who are poor should be targeted in tobacco control programs. Further studies are needed that examine perceptions of the adverse health effects and the cultural factors of waterpipe tobacco smoking. PMID:23597395

  7. Correlates of 15-Year Maintenance of Physical Activity in Middle-Aged Women

    PubMed Central

    Janssen, Imke; Dugan, Sheila A.; Karavolos, Kelly; Lynch, Elizabeth B.; Powell, Lynda H.

    2014-01-01

    Purpose To gain a better understanding of the correlates of sustained physical activity in midlife women, we used longitudinal epidemiologic data to investigate links between sustained physical activity and constructs advocated by three basic behavioral and social science theories: 1) self-determination; 2) social cognitive; and 3) social networks. Methods A random sample of 90 mid-life women, stratified by level of physical activity over 15 years, was selected from the Chicago cohort of the longitudinal Study of Women’s Health Across the Nation (SWAN). Using data on self-reported physical activity collected over 15 years, women were categorized into consistently active, spoardically active, and sedentary. New data were collected on theory-relevant constructs, i.e. autonomous motivation (assessed by the Treatment Self-Regulation Questionnaire (TSRQ)) and self-efficacy (assessed by the Self-Efficacy and Exercise Habits Survey). Every SWAN woman identified a close female friend who also completed the physical activity questionnaire. Results SWAN women with higher autonomous motivation (p=0.002) and higher self-efficacy (p<0.001) were more likely to be consistently physically active in analyses adjusted for age, race, and socioeconomic status. Sixty one percent of SWAN women with a history of consistent physical activity had a friend who is currently highly active, versus 34% and 23% for sporadically active and sedentary women, respectively (test for trend p=0.008). Conclusions In midlife women, constructs advocated by basic behavioral and social science theories were consistent with long-term patterns of physical activity behavior. Special focus should be given to these basic theories in the design of interventions to promote sustained physical activity in midlife women. PMID:23813123

  8. [15 years' results in the treatment of differentiated thyroid carcinoma in a region of endemic goiter].

    PubMed

    Perinetti, H A; Staneloni, L N; Vitale, R

    1990-01-01

    We have evaluated the results of differentiated thyroid carcinoma treatment after 15 years of follow up. The group consisted of 120 cases of papillary type and 144 cases of follicular type; the mean age of the patients was 38.2 years for papillary and 46.5 for the follicular. The ratio men/women was 1/4 for the papillary and 1/3.2 for the follicular. The prognostic factors evaluated included: a) histologic types according to WHO classification, b) clinical stage, c) age and d) sex. The staging of the disease followed the classification suggested by Smendal, stage I: intraglandular disease; stage II: regional lymph node metastases; stage III: invasion of other tissues in the neck or mediastinum and stage IV: distant metastases. The basic treatment was surgery with the use of 131I and thyroid hormone. The results were statistically analyzed with the conventional life table method or chi square. At 15 years the overall survival was 84 +/- 4% for the papillary type and 66 +/- 9% for the follicular type (p = 0.01) (Fig. 1). The patients treated in stage I had a survival of 90 +/- 5%, significantly higher than those in stage II (53 +/- 8%), p less than 0.03. In stage III and IV the small number of patients made it difficult to interpret the results statistically (Fig. 2). The age of the patients appears to be another prognostic factor. The group under 40 years had 85 +/- 5% of survival compared to 59 +/- 4% over 40 years, p less than 0.01 (Fig. 3).(ABSTRACT TRUNCATED AT 250 WORDS)

  9. Development of a Nomarski-type multi-frame interferometer as a time and space resolving diagnostics for the free electron density of laser-generated plasma

    SciTech Connect

    Boerner, M.; Frank, A.; Pelka, A.; Schaumann, G.; Schoekel, A.; Schumacher, D.; Roth, M.; Fils, J.; Blazevic, A.; Hessling, T.; Basko, M. M.; Maruhn, J.; Tauschwitz, An.

    2012-04-15

    This article reports on the development and set-up of a Nomarski-type multi-frame interferometer as a time and space resolving diagnostics of the free electron density in laser-generated plasma. The interferometer allows the recording of a series of 4 images within 6 ns of a single laser-plasma interaction. For the setup presented here, the minimal accessible free electron density is 5 x 10{sup 18} cm{sup -3}, the maximal one is 2 x 10{sup 20} cm{sup -3}. Furthermore, it provides a resolution of the electron density in space of 50 {mu}m and in time of 0.5 ns for one image with a customizable magnification in space for each of the 4 images. The electron density was evaluated from the interferograms using an Abel inversion algorithm. The functionality of the system was proven during first experiments and the experimental results are presented and discussed. A ray tracing procedure was realized to verify the interferometry pictures taken. In particular, the experimental results are compared to simulations and show excellent agreement, providing a conclusive picture of the evolution of the electron density distribution.

  10. Thirty Frames per Second

    ERIC Educational Resources Information Center

    Kelly, Bruce

    2006-01-01

    Analyzing real motion with frame-by-frame precision can be conducted using modestly priced digital-video camcorders. Although well below the 1,000 frames-per-second threshold of high-speed cameras, commercially available camcorders grab 30 frames per second. A replay dissected at this lower frequency is fun to watch, challenges students'…

  11. National survey of the oral health of 12- and 15-year-old schoolchildren in the United Arab Emirates.

    PubMed

    El-Nadeef, M A I; Al Hussani, E; Hassab, H; Arab, I A

    2009-01-01

    This paper describes the first national survey of oral health in the United Arab Emirates (UAE). Using WHO criteria, dental caries and fluorosis were recorded in 2651 schoolchildren aged 12 and 15 years, and periodontal disease in those aged 15 years. The prevalence of dental caries in the permanent teeth of 12-year-olds was 54%; the mean DMFT (number of decayed, missing or filled permanent teeth) per child was 1.6. The prevalence of dental caries in 15-year-olds was 65% and the mean DMFT was 2.5. For the UAE as a whole, 70% of 12-year-old schoolchildren had no dental fluorosis and 37% of 15-year-olds had healthy periodontal tissues.

  12. Diagnostic algorithm for unilateral sinus disease: a 15-year retrospective review

    PubMed Central

    Silva, Marianella Paz; Pinto, Jayant M.; Corey, Jacquelynne P.; Mhoon, Ernest E.; Baroody, Fuad M.; Naclerio, Robert M.

    2016-01-01

    Background Patients presenting with unilateral sinus symptoms or nasal polyps raise concerns about sinister pathology. Yet despite the relatively common occurrence of this presentation, and its potential severity, an organized diagnostic approach to unilateral sinus disease (USD) has never been defined. The purpose of this work was to propose a diagnostic algorithm for managing patients with USD based on prior experience. Methods We performed a retrospective review of the medical records of all patients with USD who underwent surgical intervention and had pathological specimens during a 15-year period at an urban academic center. Nasal endoscopy and computed tomography (CT) scan findings, demographic characteristics, presenting symptoms, medical histories, and previous treatments were analyzed. Results A total of 191 patients met the inclusion criteria, 153 of whom were initially diagnosed at our center. Among the latter group, 51 (33%) presented with a nasal mass or polyp observed by endoscopy. Inverted papilloma was present in 16% of those cases, and malignant tumors comprised 14%. In contrast, of patients without an obvious nasal polyp (n = 102), 2% had inverted papilloma and 3% had malignancies. Overall, chronic rhinosinusitis was the most common diagnosis both in patients with polyps (67%) and those without nasal polyps (69%). Conclusion Although USD is most likely to represent chronic inflammation, there exists a fair likelihood of finding malignant pathology, particularly in cases where patients have a unilateral polyp. Based on this review, we propose a strategy for the management of new presentations of USD. PMID:25880633

  13. Ethmoid pneumocele presenting with exophthalmos 15 years after endoscopic sinus surgery

    PubMed Central

    Song, Michelle; Ahn, Sun M.; Reh, Douglas R.

    2015-01-01

    Introduction: A pneumocele is an abnormal dilation of an air-containing sinus beyond the normal margins of bone, with associated bony thinning. A delayed ethmoid pneumocele after sinus surgery has not previously been reported. Methods: A case report of a patient with a delayed ethmoid pneumocele after sinus surgery. The diagnostic workup, operative approach, and postoperative results were evaluated. Results: A 57-year-old female with a history of endoscopic sinus surgery 15 years prior presented with right eye proptosis and severe orbital and facial pressure. A maxillofacial computed tomography showed a markedly expanded air-filled right anterior ethmoid space with a dehiscent lamina papyracea, consistent with a pneumocele. Marsupialization of the pneumocele as well as a revision ethmoidectomy were performed, with a visible return of the orbital contents to a more natural position. The patient experienced worsened diplopia immediately postoperatively that resolved within two weeks. Conclusions: This case demonstrates that a pneumocele can present even years after endoscopic sinus surgery, and acute but temporary development or worsening of diplopia can result from surgical decompression of the pneumocele as the eye returns to its natural position. PMID:26302735

  14. Surgical treatment of primary hyperparathyroidism due to parathyroid tumor: A 15-year experience

    PubMed Central

    Feng, Lu; Zhang, Xu; Liu, Shan-Ting

    2016-01-01

    The aim of this study was to highlight our experience over a 15-year period in dealing with primary hyperparathyroidism (PHPT) due to a parathyroid tumor. Parathyroidectomy is the standard therapy for patients with PHPT. Our study included all patients with PHPT treated by parathyroidectomy at the Affiliated Cancer Hospital of Zhengzhou University, China. Between 1998 and 2013, a total of 107 patients were recruited. Their clinical data, presentation, laboratory examinations, imageological diagnoses and surgical approaches were analyzed retrospectively. Eighty-four cases (78.5%) were followed up. During a median follow-up period of 5.7 years, a total of 80 patients were without recurrence and metastasis. The main symptoms of PHPT patients were palpable neck mass, joint pains and pathological fracture. The high levels of preoperative parathyroid hormone (PTH) and serum calcium in PHPT patients decreased to below the normal upper limit within 3 days of surgery. The sensitivity of neck ultrasonography, sestamibi scanning, CT, MRI and the combination of three or four types of test were 86.0%, 90.4%, 80.8%, 79.6% and 96.1%, respectively. A 50% or greater drop in PTH levels within 20 min compared with the highest PTH levels before surgery occurred in 95/107 cases (88.8%). Transient hypocalcemia was the most common surgical complication. The ultrasonography and sestamibi scan is the most effective examination for parathyroid tumor. The 20 min PTH measurement appears to be extremely useful, and avoids unnecessary bilateral exploration.

  15. [Pedagocic and didactic renovation for histology and embryology learning. A 15 years experience].

    PubMed

    D'Ottavio, Alberto E; Bassan, Norberto D

    2006-01-01

    This paper describes the pedagogical and didactical renovation carried out between 1986 y 2001 in the Cathedra of Histology and Embryology (Faculty of Medical Sciences, National University of Rosario). This process, initiated with pilot tests during early 70s and a full length paper in late 70s, was centered in differential activities performed by teachers and students, being adapted to the massive and no restricted admission during that period (2000 +/- 500 students). The design included individual and/or group management of self-learning and self-evaluation modules, training laboratories in microscopic diagnosis using protocols similar to clinical records, problem-solving sessions and theoretical sessions of consult and relearning, placed at the end of the aforesaid learning situations. Learning followed a decreasing support trajectory ([see text]) for reaching a systemic self-learning, relevant for incessant medical education. Its permanence and optimal results along 15 years encourage us to present this model as a valid and reliable one for Faculties with histological and embryological contents developed in a traditional formal or as a contribution to the passage from a traditional curriculum with independent subjects to other, renovated or innovative, with varied grades of integration. PMID:17639806

  16. Nonossifying fibroma (metaphyseal fibrous defect) of the mandible in a 15-year-old boy.

    PubMed

    Mannan, Abul Ala; Singh, N Gopendro; Al-Waheeb, Salah; Taher, Taher N; Mohammed, Emad El Din El Din

    2015-06-01

    We describe a rare case of nonossifying fibroma of the mandible in a 15-year-old boy who presented with a left mandibular swelling. Conventional imaging showed an expansile radiolucent lesion involving the angle and the body of the left mandible. The lesion was curetted, and a miniplate was implanted at the excision site. Microscopic examination of the removed specimen revealed a cellular lesion characterized by a proliferation of uniform spindle-shaped cells in a vague but prominent storiform pattern, which represented the classic appearance of nonossifying fibroma. Three months later, radiography detected a fracture of the implantation plate. The area was re-explored with curettage of the soft tissue, which on microscopy demonstrated findings similar to the initial curettage findings. Follow-up radiology revealed satisfactory healing of the jaw, and no further recurrence was seen 2 years after the initial surgery. We present this case to highlight the importance of recognizing nonossifying fibroma in the mandible, which can be easily confused with more common mandibular lesions. PMID:26053991

  17. Leprosy in children and adolescents under 15 years old in an urban centre in Brazil.

    PubMed

    Santos, Selton Diniz; Penna, Gerson Oliveira; Costa, Maria da Conceição Nascimento; Natividade, Marcio Santos; Teixeira, Maria Glória

    2016-05-24

    This original study describes the intra-urban distribution of cases of leprosy in residents under 15 years old in Salvador, Bahia, Brazil; the study also identifies the environment in which Mycobacterium leprae is being transmitted. The cases were distributed by operational classification, clinical forms, type of contact and the addresses were geo-referenced by neighborhood. Between 2007 and 2011, were reported 145 cases of leprosy in target population living in Salvador, corresponding to detection rates of 6.21, 6.14, 5.58, 5.41 and 6.88/100,000 inhabitants, respectively. The spatial distribution of the disease was focal. Of the 157 neighborhoods of Salvador, 44 (28.6%) notified cases of leprosy and in 22 (50%) of these were detected more than 10 cases per 100,000 inhabitants. The infectious forms were found in 40% of cases. Over 90% of cases had been living in Salvador for more than five years. Overall, 52.6% reported having had contact with another infected individual inside the household and 25% in their social circle. In Salvador, M. leprae transmission is established. The situation is a major concern, since transmission is intense at an early age, indicating that this endemic disease is expanding and contacts extend beyond individual households. PMID:27223655

  18. [Changes in food allergen sensitization rates of Japanese allergic children during the last 15 years].

    PubMed

    Kusunoki, Takashi; Miyanomae, Takeshi; Inoue, Yasuhiro; Itoh, Masatoshi; Yoshioka, Takakazu; Okafuji, Ikuo; Nishikomori, Ryuta; Heike, Toshio; Nakahata, Tatsutoshi

    2004-07-01

    In order to evaluate the changes in food allergen sensitization rates of allergic children, serum samples from 85 patients about 15 years ago (past group) and those from 90 current patients (present group) were randomly selected, and the specific IgE for six food allergens (wheat, peanuts, sesame, mackerel, ovomucoid, and kiwi) were measured with the CAP-RAST system. Sensitivity rates (class 2 or higher) for wheat and peanuts were significantly higher in the present than in the past group. Although there was no statistical difference in sensitivity rates (class 2 or higher) for kiwi between the groups, sensitivity rates (class 1 or higher) of the present group were significantly higher than those of the past group, indicating that the number of cases mildly sensitized to kiwi has been increasing. This trend was especially marked among children aged 6 or younger, and there was no statistical difference in sensitivity rates among those aged 7 or older. For the management of food allergy, special attention should therefore be paid not only to an increase in the number of patients, but also to changes in the kinds of causative foods.

  19. Clinical applications of maternal plasma fetal DNA analysis: translating the fruits of 15 years of research.

    PubMed

    Chiu, Rossa Wai Kwun; Lo, Yuk Ming Dennis

    2013-01-01

    The collection of fetal genetic materials is required for the prenatal diagnosis of fetal genetic diseases. The conventional methods for sampling fetal genetic materials, such as amniocentesis and chorionic villus sampling, are invasive in nature and are associated with a risk of fetal miscarriage. For decades, scientists had been pursuing studies with goals to develop non-invasive methods for prenatal diagnosis. In 1997, the existence of fetal derived cell-free DNA molecules in plasma of pregnant women was first demonstrated. This finding provided a new source of fetal genetic material that could be obtained safely through the collection of a maternal blood sample and provided a new avenue for the development of non-invasive prenatal diagnostic tests. Now 15 years later, the diagnostic potential of circulating fetal DNA analysis has been realized. Fruitful research efforts have resulted in the clinical implementation of a number of non-invasive prenatal tests based on maternal plasma DNA analysis and included tests for fetal sex assessment, fetal rhesus D blood group genotyping and fetal chromosomal aneuploidy detection. Most recently, research groups have succeeded in decoding the entire fetal genome from maternal plasma DNA analysis which paved the way for the achievement of non-invasive prenatal diagnosis of many single gene diseases. A paradigm shift in the practice of prenatal diagnosis has begun.

  20. Adolescent female volleyballers' (aged 13-15 years) body build classification and proficiency in competitions.

    PubMed

    Stamm, Raini; Stamm, Meelis; Koskel, Säde

    2006-12-01

    The present paper studies the body build and proficiency in the game of 74 female volleyballers aged 13-15 years from eight teams, who participated in Estonian championships. Fourteen anthropometric measurements were taken from the players, and these data were systematized into a 5 SD height-weight classification (small, medium, large, pyknomorphous and leptomorphous). The players participated in 28 matches, which were recorded in parallel with two computers equipped with the program Game. The girls' proficiency in the game was assessed in the same body build classes. For each class, the total number of serves, receptions, attacks and blocks, their mean values per player and percentage from elements performed during the whole tournament were calculated. In the same way, for each class the total number of points scored and separately the number of points scored in serve, attack and block were calculated. For each class the mean index of proficiency was calculated for serve, reception, attack and block. The results showed, that the most successful were the girls of class 3 with big height and weight. The small girls of class 1 were the least successful. The players belonging to the other classes formed an intermediate group. The authors recommend the use of the body build classification as it enables simultaneous assessment of body build and proficiency in competitions.

  1. Surgical treatment of primary hyperparathyroidism due to parathyroid tumor: A 15-year experience

    PubMed Central

    Feng, Lu; Zhang, Xu; Liu, Shan-Ting

    2016-01-01

    The aim of this study was to highlight our experience over a 15-year period in dealing with primary hyperparathyroidism (PHPT) due to a parathyroid tumor. Parathyroidectomy is the standard therapy for patients with PHPT. Our study included all patients with PHPT treated by parathyroidectomy at the Affiliated Cancer Hospital of Zhengzhou University, China. Between 1998 and 2013, a total of 107 patients were recruited. Their clinical data, presentation, laboratory examinations, imageological diagnoses and surgical approaches were analyzed retrospectively. Eighty-four cases (78.5%) were followed up. During a median follow-up period of 5.7 years, a total of 80 patients were without recurrence and metastasis. The main symptoms of PHPT patients were palpable neck mass, joint pains and pathological fracture. The high levels of preoperative parathyroid hormone (PTH) and serum calcium in PHPT patients decreased to below the normal upper limit within 3 days of surgery. The sensitivity of neck ultrasonography, sestamibi scanning, CT, MRI and the combination of three or four types of test were 86.0%, 90.4%, 80.8%, 79.6% and 96.1%, respectively. A 50% or greater drop in PTH levels within 20 min compared with the highest PTH levels before surgery occurred in 95/107 cases (88.8%). Transient hypocalcemia was the most common surgical complication. The ultrasonography and sestamibi scan is the most effective examination for parathyroid tumor. The 20 min PTH measurement appears to be extremely useful, and avoids unnecessary bilateral exploration. PMID:27602126

  2. Caustic Agent Ingestion by a 1.5-Year-Old Boy.

    PubMed

    Gharib, Behdad; Mohammadpour, Masoud; Yaghmaie, Bahareh; Sharifzadeh, Meisam; Mehdizadeh, Mehrzad; Zamani, Fatemeh; Edalatkhah, Rouhollah; Mohsenipour, Reihaneh

    2016-07-01

    We present a case of caustic ingestion by a 1.5-year-old boy. The caustic agent was drain opener which is a strong alkaline substance. Children in Iran and many other countries are still exposed to not "child proof" (child resistant packaging) toxic substance containers. Ingestion of caustic agents may lead to necrosis, perforation, and strictures. Substances that are ingested more frequently are liquid alkali material which causes severe, deep liquefaction necrosis. Common signs and symptoms of caustic agents are vomiting, drooling, refusal to drink, oral burns, stridor, hematemesis, dyspnea, dysphagia and abdominal pain. Even if no oropharyngeal lesion is seen, a significant esophageal injury which can lead to perforation and stricture cannot be ruled out. If abdominal pain or rigidity, substernal, chest or back pain exists, visceral perforation should be considered. The first thing to be checked is airway assessment. A lot of patients should be admitted to intensive care unit, and endoscopic evaluation, surgical intervention, long-term hospitalization, and worsening quality of life or among the complications. Preventive measures especially at the country level and approving proper legislation for obligating the related industries to produce child proof containers for house hold toxic products are the urgent measures to be followed by all of us.

  3. Social background, bullying, and physical inactivity: National study of 11- to 15-year-olds.

    PubMed

    Henriksen, P W; Rayce, S B; Melkevik, O; Due, P; Holstein, B E

    2016-10-01

    More children from lower social backgrounds are physically inactive than those from higher ones. We studied whether bullying was a mediating factor between lower social background and physical inactivity. We also examined the combined effect of low social class and exposure to bullying on physical inactivity. The Danish sample of the Health Behaviour in School-aged Children (HBSC) study 2006 included 6269 schoolchildren in three age groups: 11-, 13-, and 15-year-olds from a random sample of 80 schools. The students answered the internationally standardized HBSC questionnaire. The applied definition leaves 4.0% in the category physically inactive. The sex and age-adjusted OR (95% CI) for physical inactivity was 2.10 (1.39-3.18) among students with low social class and unclassifiable 3.53 (2.26-5.53). Exposure to bullying was associated with physical inactivity, sex and age-adjusted OR = 2.39 (1.67-3.41). Exposure to bullying did not explain the association between social class and physical inactivity. The association between social class and physical inactivity was more pronounced among participants also exposed to bullying. In conclusion, there was a significantly increased odds ratio for physical inactivity among students from lower social classes and for students exposed to bullying. There was a combined effect of low social class and bullying on physical inactivity.

  4. Corneal Thickness Profile and Associations in Chinese Children Aged 7 to 15 Years Old

    PubMed Central

    Ma, Yingyan; Zhu, Xiaofeng; He, Xiangui; Lu, Lina; Zhu, Jianfeng; Zou, Haidong

    2016-01-01

    Corneal thickness (CT) maps of the central (2-mm diameter), para-central (2 to 5-mm diameter), peripheral (5 to 6-mm diameter), and minimum (5-mm diameter) cornea were measured in normal Chinese school children aged 7 to 15 years old using Fourier-domain optical coherence tomography. Multiple regression analyses were performed to explore the effect of associated factors [age, gender, refraction, axial length and corneal curvature radius (CCR)] on CT and the relationship between central corneal thickness (CCT) and intraocular pressure (IOP). A total of 1228 eyes from 614 children were analyzed. The average CCT was 532.96 ± 28.33 μm for right eyes and 532.70 ±28.45 μm for left eyes. With a 10 μm increase in CCT, the IOP was elevated by 0.37 mm Hg, as measured by noncontact tonometry. The CT increased gradually from the center to the periphery. The superior and superior nasal regions had the thickest CTs, while the thinnest points were primarily located in the inferior temporal cornea. The CCT was associated with CCR (p = 0.008) but not with gender (p = 0.075), age (p = 0.286), axial length (p = 0.405), or refraction (p = 0.985). In the para-central region and the peripheral cornea, increased CT was associated with younger age, male gender, and a flatter cornea. PMID:26751798

  5. Gout in a 15-year-old boy with juvenile idiopathic arthritis: a case study

    PubMed Central

    2014-01-01

    Joint pain is a common complaint in pediatrics and is most often attributed to overuse or injury. In the face of persistent, severe, or recurrent symptoms, the differential typically expands to include bony or structural causes versus rheumatologic conditions. Rarely, a child has two distinct causes for joint pain. In this case, an obese 15-year-old male was diagnosed with gout, a disease common in adults but virtually ignored in the field of pediatrics. The presence of juvenile idiopathic arthritis (JIA) complicated and delayed the consideration of this second diagnosis. Indeed, the absence of gout from this patient’s differential diagnosis resulted in a greater than two-year delay in receiving treatment. The patients’ BMI was 47.4, and he was also mis-diagnosed with osteochondritis dissecans and underwent medical treatment for JIA, assorted imaging studies, and multiple surgical procedures before the key history of increased pain with red meat ingestion, noticed by the patient, and a subsequent elevated uric acid confirmed his ultimate diagnosis. With the increased prevalence of obesity in the adolescent population, the diagnosis of gout should be an important consideration in the differential diagnosis for an arthritic joint in an overweight patient, regardless of age. PMID:24393408

  6. Social background, bullying, and physical inactivity: National study of 11- to 15-year-olds.

    PubMed

    Henriksen, P W; Rayce, S B; Melkevik, O; Due, P; Holstein, B E

    2016-10-01

    More children from lower social backgrounds are physically inactive than those from higher ones. We studied whether bullying was a mediating factor between lower social background and physical inactivity. We also examined the combined effect of low social class and exposure to bullying on physical inactivity. The Danish sample of the Health Behaviour in School-aged Children (HBSC) study 2006 included 6269 schoolchildren in three age groups: 11-, 13-, and 15-year-olds from a random sample of 80 schools. The students answered the internationally standardized HBSC questionnaire. The applied definition leaves 4.0% in the category physically inactive. The sex and age-adjusted OR (95% CI) for physical inactivity was 2.10 (1.39-3.18) among students with low social class and unclassifiable 3.53 (2.26-5.53). Exposure to bullying was associated with physical inactivity, sex and age-adjusted OR = 2.39 (1.67-3.41). Exposure to bullying did not explain the association between social class and physical inactivity. The association between social class and physical inactivity was more pronounced among participants also exposed to bullying. In conclusion, there was a significantly increased odds ratio for physical inactivity among students from lower social classes and for students exposed to bullying. There was a combined effect of low social class and bullying on physical inactivity. PMID:26454139

  7. Gout in a 15-year-old boy with juvenile idiopathic arthritis: a case study.

    PubMed

    Morris, Hallie; Grant, Kristen; Khanna, Geetika; White, Andrew J

    2014-01-06

    Joint pain is a common complaint in pediatrics and is most often attributed to overuse or injury. In the face of persistent, severe, or recurrent symptoms, the differential typically expands to include bony or structural causes versus rheumatologic conditions. Rarely, a child has two distinct causes for joint pain. In this case, an obese 15-year-old male was diagnosed with gout, a disease common in adults but virtually ignored in the field of pediatrics. The presence of juvenile idiopathic arthritis (JIA) complicated and delayed the consideration of this second diagnosis. Indeed, the absence of gout from this patient's differential diagnosis resulted in a greater than two-year delay in receiving treatment. The patients' BMI was 47.4, and he was also mis-diagnosed with osteochondritis dissecans and underwent medical treatment for JIA, assorted imaging studies, and multiple surgical procedures before the key history of increased pain with red meat ingestion, noticed by the patient, and a subsequent elevated uric acid confirmed his ultimate diagnosis. With the increased prevalence of obesity in the adolescent population, the diagnosis of gout should be an important consideration in the differential diagnosis for an arthritic joint in an overweight patient, regardless of age.

  8. Caustic Agent Ingestion by a 1.5-Year-Old Boy.

    PubMed

    Gharib, Behdad; Mohammadpour, Masoud; Yaghmaie, Bahareh; Sharifzadeh, Meisam; Mehdizadeh, Mehrzad; Zamani, Fatemeh; Edalatkhah, Rouhollah; Mohsenipour, Reihaneh

    2016-07-01

    We present a case of caustic ingestion by a 1.5-year-old boy. The caustic agent was drain opener which is a strong alkaline substance. Children in Iran and many other countries are still exposed to not "child proof" (child resistant packaging) toxic substance containers. Ingestion of caustic agents may lead to necrosis, perforation, and strictures. Substances that are ingested more frequently are liquid alkali material which causes severe, deep liquefaction necrosis. Common signs and symptoms of caustic agents are vomiting, drooling, refusal to drink, oral burns, stridor, hematemesis, dyspnea, dysphagia and abdominal pain. Even if no oropharyngeal lesion is seen, a significant esophageal injury which can lead to perforation and stricture cannot be ruled out. If abdominal pain or rigidity, substernal, chest or back pain exists, visceral perforation should be considered. The first thing to be checked is airway assessment. A lot of patients should be admitted to intensive care unit, and endoscopic evaluation, surgical intervention, long-term hospitalization, and worsening quality of life or among the complications. Preventive measures especially at the country level and approving proper legislation for obligating the related industries to produce child proof containers for house hold toxic products are the urgent measures to be followed by all of us. PMID:27424019

  9. Giant cell interstitial pneumonia in a 15-year-old boy.

    PubMed

    Kakugawa, Tomoyuki; Mukae, Hiroshi; Nagata, Towako; Ishii, Hiroshi; Kaida, Hideyuki; Hayashi, Tomayoshi; Suematsu, Takashi; Kadota, Jun-ichi; Kohno, Shigeru

    2002-11-01

    Giant cell interstitial pneumonia (GIP) is a very uncommon respiratory disease. We report a juvenile patient with GIP aged 15 years. Although he has a negative past history of direct exposure to hard metals, we could not exclude possible exposure in very small amounts through his parents. Microscopic examination of lung biopsy specimen obtained by video-assisted thoracoscopy revealed marked cellular interstitial infiltrates and prominent intraalveolar macrophages as well as giant cells showing cellular cannibalism. Analysis of the biopsied lung tissue for cobalt and tungsten was negative. Clinical symptoms, laboratory, and radiological findings improved markedly after treatment with corticosteroids. To our knowledge, only eleven cases of GIP have been reported in Japan. Although possible exposure to hard metals was identified in 9 of the 11 reported cases, there is no clear dose-dependent relationship with onset and prognosis. The average age at onset was 46.2+/-15.0 years. Our patient is the youngest case of GIP reported in the world. PMID:12487179

  10. Bilateral Total Knee Arthroplasty in a 15 Year Old With Skeletal Dysplasia and Open Physes.

    PubMed

    Ho, Jason C; Siqueira, Marcelo B P; Jacob, Paul; Goodwin, Ryan C; Barsoum, Wael K

    2016-05-01

    There are limited reports of total knee arthroplasty (TKA) in the pediatric population. The use of constrained, stemmed components is particularly unusual in the setting of open physes due to concerns with growth arrest and implant survivorship. The current authors describe a 15-year-old boy with open growth plates and an epiphyseal dysplasia-like condition affecting the knees bilaterally. He had no other significant medical or orthopedic conditions and his genetic workup was negative. He had severe knee pain and a bilateral 40° valgus with severe lateral compartment arthritis. Conservative treatment provided no symptom relief, and the patient had been wheelchair bound for 18 months prior to presentation. Treatment with simultaneous bilateral TKA using cemented, stemmed, and constrained components was undertaken. There were no intraoperative complications, and his final follow-up was at 5.6 years postoperatively. Radiographic evaluation at follow-up showed that components were well placed with no loosening. The patient had pain-free motion and a perfect Knee injury and Osteoarthritis Outcome Score. Based on the review of the literature and the outcomes of this case, the authors believe simultaneous bilateral TKA using cemented, stemmed, and constrained components is a reasonable option for joint reconstruction in the pediatric patient with open physes who also has significant arthritis and deformity not of oncologic origin. [Orthopedics. 2016; 39(3):e549-e552.]. PMID:27045485

  11. Leprosy in children and adolescents under 15 years old in an urban centre in Brazil

    PubMed Central

    Santos, Selton Diniz; Penna, Gerson Oliveira; Costa, Maria da Conceição Nascimento; Natividade, Marcio Santos; Teixeira, Maria Glória

    2016-01-01

    This original study describes the intra-urban distribution of cases of leprosy in residents under 15 years old in Salvador, Bahia, Brazil; the study also identifies the environment in which Mycobacterium leprae is being transmitted. The cases were distributed by operational classification, clinical forms, type of contact and the addresses were geo-referenced by neighborhood. Between 2007 and 2011, were reported 145 cases of leprosy in target population living in Salvador, corresponding to detection rates of 6.21, 6.14, 5.58, 5.41 and 6.88/100,000 inhabitants, respectively. The spatial distribution of the disease was focal. Of the 157 neighborhoods of Salvador, 44 (28.6%) notified cases of leprosy and in 22 (50%) of these were detected more than 10 cases per 100,000 inhabitants. The infectious forms were found in 40% of cases. Over 90% of cases had been living in Salvador for more than five years. Overall, 52.6% reported having had contact with another infected individual inside the household and 25% in their social circle. In Salvador, M. leprae transmission is established. The situation is a major concern, since transmission is intense at an early age, indicating that this endemic disease is expanding and contacts extend beyond individual households. PMID:27223655

  12. Micronutrient interventions on cognitive performance of children aged 5-15 years in developing countries.

    PubMed

    Khor, Geok Lin; Misra, Snigdha

    2012-01-01

    It is estimated that more than 200 million young children worldwide fail to reach their potential in cognitive development owing to undernutrition. Numerous studies have assessed the effects of micronutrient supplementation on growth and cognitive development in infants, toddlers and preschoolers. However, micronutrient interventions on the cognitive performance of older children are limited. This article seeks to provide an update on micronutrient interventions and cognitive outcomes among children aged 5-15 years in developing countries. A total of 13 randomized controlled trials published since 2000 were identified. Majority of these studies assessed the effects of micronutrient-fortified foods on various domains of cognitive function. Among key micronutrients assessed were iron, zinc, iodine and vitamin A. This review found a lack of consistency in the impact of micronutrient supplementation on intelligence, long term mental functions and school examination grades of the children. A beneficial effect of micronutrient supplementation on short term memory was more consistently reported. Overall, the evidence from this review for the impact of micronutrients on cognitive performance in older children remains equivocal. In light of the growing interest on the influence of nutrition on cognition, it is important that culturally-appropriate and sufficiently sensitive assessment tools be used for measuring the desired cognitive outcomes that are most likely to be affected by the nutrients under study. PMID:23017305

  13. Results of proximal gastric vagotomy over 1-5 years in a district general hospital.

    PubMed

    Makey, D A; Tovey, F I; Heald, R J

    1979-01-01

    One hundred and seventy-three underwent proximal gastric vagotomy for duodenal ulceration over a 6-year period. One hundred and fifteen of these have been followed up for 1-5 years. The operative mortality was nil and the result was satisfactory in 91 per cent. The incidence of side effects was small, notably that of dumping being 2.4 per cent and of diarrhoea, 3.6 per cent. Incidence of postoperative heartburn was reduced from 13 per cent to 4 per cent by the introduction of hepatic interposition. The incidence of recurrent ulceration was 5.1 per cent after an average interval of 2 years and that of new gastric ulceration 2.6 per cent after an average of 4 years. There were no recurrent ulcers in those who had peroperative Burge tests, although secretory studies showed no difference between those tested and those not tested. Most recurrences occurred in the earliest cases operated on before Burge testing was introduced and when only 2 cm of the lower oesophagus were exposed.

  14. University of the seas, 15 years of oceanographic schools on board of the Marion Dufresne

    NASA Astrophysics Data System (ADS)

    Malaize, Bruno; Deverchere, Jacques; Leau, Hélène; Graindorge, David

    2015-04-01

    Since the first University at Sea, proposed by two French Universities (Brest and Bordeaux) in 1999, the R/V Marion Dufresne, in collaboration with the French Polar institute (IPEV), has welcome 12 oceanographic schools. The main objective of this educational and scientific program is to stimulate the potential interest of highly graduated students in scientific fields dealing with oceanography, and to broaden exchanges with foreign universities, strengthening a pool of excellence at a high international scientific level. It is a unique opportunity for the students to discover and to be involved in the work in progress of collecting scientific data on board of a ship, and to attend international research courses given by scientists involved in the cruise program. They also experience the final task of the scientific work by presenting their own training results, making posters on board, and writing a cruise report. For some University at Sea, students had also updated a daily journal, available on internet, hosted by the main institutions involved (as IPEV or EPOC, Bordeaux University). All this work is done in English, a common language to all the participants. An overview of these 15 years background experience will be presented, underlying the financial supports used, the logistic on board, as well as all the benefits acquiered by all former students, now in permanent positions in different international institutions.

  15. Corneal Epithelium Thickness Profile in 614 Normal Chinese Children Aged 7–15 Years Old

    PubMed Central

    Ma, Yingyan; He, Xiangui; Zhu, Xiaofeng; Lu, Lina; Zhu, Jianfeng; Zou, Haidong

    2016-01-01

    The purpose of the study is to describe the values and distribution of corneal epithelium thickness (CET) in normal Chinese school-aged children, and to explore associated factors with CET. CET maps were measured by Fourier-domain optical coherence tomography (FD-OCT) in normal Chinese children aged 7 to 15 years old from two randomly selected schools in Shanghai, China. Children with normal intraocular pressure were further examined for cycloplegic autorefraction, corneal curvature radius (CCR) and axial length. Central (2-mm diameter area), para-central (2- to 5-mm diameter area), and peripheral (5- to 6-mm diameter area) CET in the superior, superotemporal, temporal, inferotemporal, inferior, inferonasal, nasal, superonasal cornea; minimum, maximum, range, and standard deviation of CET within the 5-mm diameter area were recorded. The CET was thinner in the superior than in the inferior and was thinner in the temporal than in the nasal. The maximum CET was located in the inferior zone, and the minimum CET was in the superior zone. A thicker central CET was associated with male gender (p = 0.009) and older age (p = 0.037) but not with CCR (p = 0.061), axial length (p = 0.253), or refraction (p = 0.351) in the multiple regression analyses. CCR, age, and gender were correlated with para-central and peripheral CET. PMID:27004973

  16. Choledochoduodenostomy. Analysis of 71 cases followed for 5 to 15 years.

    PubMed Central

    Escudero-Fabre, A; Escallon, A; Sack, J; Halpern, N B; Aldrete, J S

    1991-01-01

    To investigate the long-term effectiveness of choledochoduodenostomy (CDD), the experience with 71 patients followed for 5 or more years after CDD was analyzed retrospectively. From 1968 to 1984, 134 patients underwent CDD. Eight patients (6%) died in the immediate postoperative period, 55 left the hospital, 8 of them were lost to follow-up, and 47 were followed but died before 5 years elapsed after CDD. The remaining 71 patients form the data base for this analysis: 38 were followed for more than 5 years, 25 were followed for more than 10 years, and 8 were followed for more than 15 years (mean 12.1 years +/- 1.3 SEM). Choledocholithiasis, chronic pancreatitis, and postoperative stricture were the indications for CDD. Cholangitis was observed in only three patients. The diameter of the common bile duct (CBD) was large in most patients (mean 18 mm +/- 0.9 SEM). These results infer that CDD is effective to treat non-neoplastic obstructing lesions of the distal CBD on a long-term basis and that the presence of a dilated CBD (more than 16 mm) that allows the construction of a CDD more than 14 mm is essential to obtain good results. PMID:2039295

  17. X-ray Sources in the Magellanic Clouds: analysis of 15 Years of XMM-Newton and Chandra Observations

    NASA Astrophysics Data System (ADS)

    Yang, J.; Laycock, S.; Christodoulou, D.; Drake, J.; Fingerman, S.; Hong, J.; Zezas, A.; Antoniou, V.; Coe, M.; Ho, W.

    2016-06-01

    Using ˜160 XMM-Newton, ˜180 Chandra, and all weekly RXTE observations, we have generated a comprehensive library of the known pulsars in the Small and Large Magellanic Clouds (SMC, LMC). We classify various pulsar properties in the range of log L_{X}=32-38 erg s^{-1} and incorporate related parameters in theoretical models. With the high time-resolution data of the EPIC and Chandra cameras and the latest calibration files and software, our 15 year pipeline generates a suite of useful products for each pulsar detection: event lists, high time-resolution light curves, periodograms, spectra, and complete histories of the dot{P}, the pulse fraction, etc., in the broad, soft (0.2-2 keV), and hard (2-12 keV) energy bands. After combining the observations from these telescopes, we found that 15 pulsars are clearly spinning up and another 15 pulsars are distinctly spinning down. We also used the faintest and brightest sources to map out the propeller line and the Eddington line, respectively. We compared the observed pulse profiles to geometric models of X-ray emission in order to constrain the physical parameters of the pulsars. We are preparing a public release of this library so that it can be used by other groups as well.

  18. A greigite-based magnetostratigraphic time frame for the Late Miocene to Recent DSDP Leg 42B cores from the Black Sea

    NASA Astrophysics Data System (ADS)

    Van Baak, Christiaan; Vasiliev, Iuliana; Palcu, Dan; Dekkers, Mark; Krijgsman, Wout

    2016-05-01

    Throughout the Late Neogene, the Black Sea experienced large paleoenvironmental changes, switching between (anoxic) marine conditions when connected to the Mediterranean Sea and (oxic) freshwater conditions at times of isolation. We create a magnetostratigraphic time frame for three sites drilled during Deep Sea Drilling Project (DSDP) Leg 42B to the Black Sea (drilled in 1975). At the time, magnetostratigraphic dating was impossible because of the presence of the little understood iron sulfide mineral greigite (in sediments a precursor to pyrite) as magnetic carrier. Our rock-magnetic results indicate that only anoxic conditions result in poor magnetic signal, likely as a result of pyrite formation in the water column rather than in the sediment. The magnetostratigraphic results indicate that Hole 379A, drilled in the basin center, has a continuous sedimentary record dating back to 1.3 Ma. Hole 380/380A is subdivided into three consistent intervals, 0-700 mbsf, 700-860 mbsf and 860-1075 mbsf. The top unit covers the Pleistocene but the magnetostratigraphy is likely compromised by the presence of mass transport deposits. The middle unit spans between 4.3 and 6.1 Ma and records continuous deposition at ~10 cm/kyr. The lower unit lacks the independent age constraints to correlate the obtained magnetostratigraphy. Hole 381 is drilled on the Bosporus slope and as a result, hiatuses are common. A correlation to the nearby Hole 380/380A is proposed, but indicates deposits cannot straightforwardly be traced across the slope. Our improved age model does not support the original interpretation based on these cores of a desiccation of the Black Sea during the Messinian salinity crisis.

  19. A 15 year legacy of cloud and atmosphere observations in Barrow, Alaska

    NASA Astrophysics Data System (ADS)

    Shupe, M.

    2012-12-01

    For the past 15 years, the U.S. Department of Energy Atmospheric Radiation Measurement (ARM) Program has operated the North Slope of Alaska (NSA) atmospheric observatory in Barrow, Alaska. Barrow offers many valuable perspectives on the Arctic environment that complement observations at lower latitudes. Unique features of the Arctic region include cold and dry atmospheric conditions, strong annual variability in sun light, a seasonally high-reflective surface, and persistent clouds that involve mixed-phase processes. ARM's ultimate objective with its flagship observatory at the northernmost point in U.S. territory is to provide measurements that can be used to improve the understanding of these atmospheric physical and radiative properties and processes such that they can be better represented in climate models. The NSA is the most detailed and long-lasting cloud-radiation-atmosphere observatory in the Arctic, providing continuous, sophisticated measurements of climate-relevant parameters. Instrument suites include active radars and lidars at various frequencies, passive radiometers monitoring radiation in microwave, infrared, visible and ultraviolet wavelengths, meteorological towers, and sounding systems. Together these measurements are used to characterize many of the important properties of clouds, aerosols, atmospheric radiation, dynamics, thermodynamics, and the surface. The coordinated nature of these measurements offers important multi-dimensional insight into many fundamental processes linking these different elements of the climate system. Moreover, the continuous operations of the facility support these observations over the full diurnal cycle and in all seasons of the year. This presentation will highlight a number of important studies and key findings that have been facilitated by the NSA observations during the first 15 years in operation. Some of these include: a thorough documentation of clouds, their occurrence frequency, phase, microphysical

  20. Short Time Impulse Response Function (STIRF) for automatic evaluation of the variation of the dynamic parameters of reinforced concrete framed structures during strong earthquakes.

    NASA Astrophysics Data System (ADS)

    Carlo Ponzo, Felice; Ditommaso, Rocco

    2015-04-01

    the results provided in this study, the methodology seems to be able to evaluate fast variations (over time) of dynamic parameters of a generic reinforced concrete framed structure. Further analyses are necessary to better calibrate the length of the moving time-window (in order to minimize the spurious frequency within each Interferometric Response Function evaluated on both weak and strong motion phases) and to verify the possibility to use the STIRF to analyse the nonlinear behaviour of general systems. Acknowledgements This study was partially funded by the Italian Civil Protection Department within the project DPC-RELUIS 2014 - RS4 ''Seismic observatory of structures and health monitoring''. References R. Ditommaso, F.C. Ponzo (2015). Automatic evaluation of the fundamental frequency variations and related damping factor of reinforced concrete framed structures using the Short Time Impulse Response Function (STIRF). Engineering Structures, 82 (2015), 104-112. http://dx.doi.org/10.1016/j.engstruct.2014.10.023.

  1. [Social stratification and nutritional anthropometry in children under 15 years old La Escalera, Lara State, Venezuela].

    PubMed

    Torres-Villanueva, Mario; Dellán-Rodríguez, Graciela; Papale-Centofanti, Jham; Rodríguez, Dioslibeth; Mendoza, Norelis; Berné, Yelitza

    2007-09-01

    Malnutrition is a public health problem for underdeveloped countries. From the 852 million of undernourished estimated by FAO between 2000 and 2002, 815 million belonged to underdeveloped countries, 28 million to countries in transition and 9 million to developed countries. Malnutrition in Venezuela had a 6% raise between 2000 and 2002, when it went from 11% to 17%. This work was done with children under 15 years old from La Escalera, using classic indicators and their combination, relating them with socioeconomic conditions, through the NBI and Graffar Méndez Castellano methods, as to consider the population nutritional profile. The higher prevalence corresponded to normal nutritional values, which oscillated between 55,7% and 80,7% in the 7-14 years old group and the 2-6 years old group, respectively. Malnutrition was found in the under 2 years old group and 7-14 years old group, with values ranging between 12,5 and 41,0% respectively. The least prevalence was found for excess malnutrition. 100% of the families in this study are poor, according to NBI; although the Graffar Mendez Castellano method established that poverty was about 60%, while 40% belonged to a medium-low status. Relating nutritional diagnosis with social stratification and the mother's educational level, three patterns were observed: III, IV and V, prevailing normal diagnosis, followed by malnutrition by deficit and malnutrition by excess, respectively. The predominating mother's educational level corresponded to incomplete high school, followed by analphabetism and the least prevalent has complete basic elementary education. It should be noted that the nutrition deficit was inversely related to the socioeconomic stratification and the mother's educational level.

  2. Survey of rehabilitation support for children 0–15 years in a rural part of Kenya

    PubMed Central

    Gona, Joseph K.; Odera-Mung’ala, Victor; Newton, Charles R.; Geere, Jo-Anne; Hong, Chia Swee; Hartley, Sally

    2014-01-01

    Purpose Information regarding the nature, availability and distribution of rehabilitation services for children with disabilities across developing countries is scarce, and data that do exist are of variable quality. If planning and development are to progress, information about service provision is vital. The aim was to establish the scope and nature of rehabilitation support available to children with disabilities (0–15 years) and their families in rural Kenya. Method A comprehensive sample comprising service provision in the health and special education sectors was established. Non-governmental and community-based organisations were also included. A survey of rehabilitation services was conducted through examination of service-related documentation and key informant interviews with the heads of services. Results Rehabilitation comprised hospital-based occupational therapy, physiotherapy and orthopaedic technology; and seven special education establishments plus an education assessment resource centre. There was one non-government organisation and one community-based organisation relevant to children with disabilities. Activities focused on assessment, diagnosis and raising community awareness. Provision was challenged by inadequate staffing, resources and transport. Government funding was supplemented variously by donations and self-sufficiency initiatives. Rehabilitation approaches appeared to be informed by professional background of practitioner, rather than the needs of child. Service documentation revealed use of inconsistent recording methods. Conclusions The data highlight the challenges of rehabilitation, demanding greater investment in personnel and their training, more material resources, improved access to the community and better recording mechanisms. Implications for Rehabilitation There needs to be greater investment in rehabilitation provision in developing countries. Consideration of community-based initiatives is required to support better

  3. Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research.

    PubMed

    Parrott, A. C.

    2001-12-01

    MDMA (3,4-methylenedioxymethamphetamine) or 'Ecstasy' was scheduled as an illegal drug in 1986, but since then its recreational use has increased dramatically. This review covers 15 years of research into patterns of use, its acute psychological and physiological effects, and the long-term consequences of repeated use. MDMA is an indirect monoaminergic agonist, stimulating the release and inhibiting the reuptake of serotonin (5-HT) and, to a lesser extent, other neurotransmitters. Single doses of MDMA have been administered to human volunteers in double-blind placebo-controlled trials, although most findings are based upon recreational MDMA users. The 'massive' boost in neurotransmitter activity can generate intense feelings of elation and pleasure, also hyperactivity and hyperthermia. This psychophysiological arousal may be exacerbated by high ambient temperatures, overcrowding, prolonged dancing and other stimulant drugs. Occasionally the 'serotonin syndrome' reactions may prove fatal. In the days after Ecstasy use, around 80% of users report rebound depression and lethargy, due probably to monoaminergic depletion. Dosage escalation and chronic pharmacodynamic tolerance typically occur in regular users. Repeated doses of MDMA cause serotonergic neurotoxicity in laboratory animals, and there is extensive evidence for long-term neuropsychopharmacological damage in humans. Abstinent regular Ecstasy users often display reduced levels of 5-HT, 5-HIAA, tryptophan hydroxylase and serotonin transporter density; functional deficits in learning/memory, higher cognitive processing, sleep, appetite and psychiatric well-being, and, most paradoxically, 'loss of sexual interest/pleasure'. These psychobiological deficits are greatest in heavy Ecstasy users and may reflect serotonergic axonal loss in the higher brain regions, especially the frontal lobes, temporal lobes and hippocampus. These problems seem to remain long after the recreational use of Ecstasy has ceased

  4. Malaysia family-planning centers strive to maintain gains won in 15-year period.

    PubMed

    Roemer, R

    1968-09-12

    Family planning in Malaysia is discussed. Family planning began in Malaysia about 15 years ago through the efforts of voluntary family Planning Associations in the various Malay states. In 1966 the Malaysian Parliament passed the National Family Planning Act setting up the National FAmily Planning Board to formulate policies and methods for the promotion and spread of family planning knowledge and practice on the grounds of health of mothers and children and welfare of the family. In 1967, the board set a target of 40,000 new acceptors of family planning and 90% of the target was reached. This represents 3% of the child-bearing married women aged 15-49. The target for 1968 of 65,000 new acceptors is being achieved. A survey of acceptors is to be carried out from December 1968 to April 1969 to ascertain how many women who accepted family planning continue to practice it. Malaysia's crude birth rate declined from 46.2 in 1957 to 37.3 in 1966 before the government program was instituted. Abortion attempts have been frequent. The main method of contraception used is oral contraceptives. According to a 1957 survey, 31% of the married women in the metropolitan areas and 2% of rural women were using contraception. Presently, in Malaysia there is a need to: 1) train personnel to provide services, 2) inform and motivate families to accept family planning, 3) continue a broad educational program, 4) reform Malaysia's antiquated abortion law, and 5) integrate family planning services more fully into the general health services of the country.

  5. A 15-Year-Old Male Baseball Player With a Mass in the Brachialis Muscle.

    PubMed

    Golub, Ivan J; Garcia, Roberto A; Wittig, James C

    2016-05-01

    A 15-year-old boy presented with a mass in his right arm after suffering a minor injury playing baseball. He had been diagnosed with a hematoma. There was no other outstanding medical/surgical history. Magnetic resonance images showed a heterogeneous mass arising from the brachialis muscle that mainly enhanced peripherally with extremely scant internal nodular enhancement. Core needle biopsy cells were positive for CD31 and CD34, markers for atypical endothelial cells, as well as MIB-1 and p53. The final diagnosis was an angiosarcoma of the brachialis muscle. Pediatric angiosarcoma, particularly within deep tissue, is exceedingly rare. Histological and immunohistochemical modalities led to the diagnosis. Magnetic resonance images suggested a mass with a large cystic/hemorrhagic space that could have been misconstrued as a hematoma had there been absolutely no nodular or septal enhancement. The patient underwent neoadjuvant chemotherapy and radiation before undergoing limb-sparing surgery that included resection of the mass with the brachialis muscle and short head of the biceps muscle. Neoadjuvant treatment was deemed successful due to a drastic reduction in the size of the tumor and 95% tumor necrosis. The patient was disease free 2 years postoperatively. There had been no local/systemic recurrences. He was pain free, had normal elbow function, and had returned to playing baseball. It is important to be extremely suspicious when a patient presents with a hemorrhagic, painless, enlarging mass after sustaining minor trauma. A careful and meticulous biopsy must be completed to achieve the correct diagnosis. Magnetic resonance imaging with gadolinium is recommended for evaluation because these masses can be often misinterpreted as hematomas. [Orthopedics. 2016; 39(3):e545-e548.].

  6. REOPERATION FOR INTRACRANIAL HYPERTENSION IN TWIST1 CONFIRMED SAETHRE-CHOTZEN SYNDROME: A 15 YEAR REVIEW

    PubMed Central

    Woods, Roger H; Ul-Haq, Ehtesham; Wilkie, Andrew OM; Jayamohan, Jayaratnam; Richards, Peter G; Johnson, David; Lester, Tracy; Wall, Steven A

    2009-01-01

    Background Saethre-Chotzen syndrome (SCS) is a syndromic craniosynostosis defined by a genetic mutation affecting the TWIST1 gene on chromosome 7p21. SCS is typically associated with uni- or bi-coronal synostosis, eyelid ptosis, dysmorphic external ears and other variable facial and limb abnormalities. Surgical management of the craniosynostosis addresses the calvarial deformity and may relieve or reduce risk of intracranial hypertension. The aim of this study was to assess surgical intervention, with particular consideration of reoperation rate for intracranial hypertension, in SCS patients. Method A retrospective casenote analysis was performed on all patients with a confirmed TWIST1 gene abnormality, who attended the Oxford Craniofacial Unit over a 15-year period. Each patient’s mutation and clinical features were recorded. Surgical intervention and sequelae were examined in greater detail. Results Thirty-four patients with genetically confirmed SCS were identified. All had craniosynostosis (bicoronal 76%, unicoronal 18%, bicoronal and sagittal 6%), and the majority had eyelid ptosis, low frontal hairline and external ear anomalies. Thirty-one cases had received surgical intervention. Nine of 26 patients (35%) with minimum 12 month follow-up after primary intervention, and 8 of 19 patients (42%) with minimum 5 year follow-up, developed intracranial hypertension necessitating secondary calvarial surgery. Conclusions Despite standard surgical intervention, patients with SCS have a high rate (35 - 42%) of recurrent intracranial hypertension necessitating further surgical expansion. All patients with either bicoronal synostosis or unicoronal synostosis with syndromic features, should be screened for TWIST1 mutations as this confers a greater risk than non-syndromic synostosis of the same sutures. Regular follow-up of SCS patients throughout the childhood years is essential. PMID:19483581

  7. A 15-Year-Old Male Baseball Player With a Mass in the Brachialis Muscle.

    PubMed

    Golub, Ivan J; Garcia, Roberto A; Wittig, James C

    2016-05-01

    A 15-year-old boy presented with a mass in his right arm after suffering a minor injury playing baseball. He had been diagnosed with a hematoma. There was no other outstanding medical/surgical history. Magnetic resonance images showed a heterogeneous mass arising from the brachialis muscle that mainly enhanced peripherally with extremely scant internal nodular enhancement. Core needle biopsy cells were positive for CD31 and CD34, markers for atypical endothelial cells, as well as MIB-1 and p53. The final diagnosis was an angiosarcoma of the brachialis muscle. Pediatric angiosarcoma, particularly within deep tissue, is exceedingly rare. Histological and immunohistochemical modalities led to the diagnosis. Magnetic resonance images suggested a mass with a large cystic/hemorrhagic space that could have been misconstrued as a hematoma had there been absolutely no nodular or septal enhancement. The patient underwent neoadjuvant chemotherapy and radiation before undergoing limb-sparing surgery that included resection of the mass with the brachialis muscle and short head of the biceps muscle. Neoadjuvant treatment was deemed successful due to a drastic reduction in the size of the tumor and 95% tumor necrosis. The patient was disease free 2 years postoperatively. There had been no local/systemic recurrences. He was pain free, had normal elbow function, and had returned to playing baseball. It is important to be extremely suspicious when a patient presents with a hemorrhagic, painless, enlarging mass after sustaining minor trauma. A careful and meticulous biopsy must be completed to achieve the correct diagnosis. Magnetic resonance imaging with gadolinium is recommended for evaluation because these masses can be often misinterpreted as hematomas. [Orthopedics. 2016; 39(3):e545-e548.]. PMID:27045482

  8. Salivary gland tumours: a 15-year review at the Dental Centre Lagos University Teaching Hospital.

    PubMed

    Ladeinde, A L; Adeyemo, W L; Ogunlewe, M O; Ajayi, O F; Omitola, O G

    2007-12-01

    The aim of this study was to determine the relative frequency of tumours of the salivary gland seen at the Dental Centre, Lagos University Teaching Hospital, Nigeria over a period of 15 years. All cases that were histologically diagnosed as salivary gland tumours from January 1990 to December 2004 were retrieved from the histopathology records of the Department of Oral Pathology and Biology and Department of Oral and Maxillofacial Surgery of the Lagos University Teaching Hospital, Lagos, Nigeria. All the cases were subjected to analysis of age, sex, site of occurrence and histologic diagnosis based on 1991 World Health Organisation (WHO) classification. Salivary gland constituted 6.3% of all oro-facial tumours and tumour-like lesions. The frequency of malignant tumours was 60.8% (n = 73) and benign tumours 39.2% (n = 47). Minor salivary glands (63.3%) were mostly affected. The male-to-female ratio was 1.1:1, and most (72.5%) of the tumours occurred in the age group of 21-60 years. Pleomorphic adenoma was the most commonly occurring tumour (29.2%) followed by adenoid cystic carcinoma (19.2%). The predominant benign and malignant tumours were pleomorphic adenoma and adenoid cystic carcinoma respectively. Palate (45.8%) was the most frequently affected site. The mean.age (+/-SD) of patients with benign tumours was significantly lower than those with malignant tumours (P = 0.003). The incidence of salivary gland tumours in this study is higher than in most previous reports. Malignant tumours which occurred in older age group were the most commonly seen.

  9. Quality of life in families of Croatian veterans 15 years after the war.

    PubMed

    Zdjelarević, Ana; Komar, Zoran; Loncar, Mladen; Plasć, Ivana Dijanić; Hrabac, Pero; Groznica, Ivana; Marcinko, Darko

    2011-01-01

    Exposure to war trauma with its consequences such as post traumatic stress disorder (PTSD) and disability due to combat injuries poses a significant problem for modern Croatian society. However, this is also a public health problem requiring continuous study of effective treatment strategies to achieve an increase in quality of life of most war-affected groups. Aim of this study was to examine the quality of life of population most affected by war - families of Croatian veterans. Present study included 126 female participants, who agreed to complete physical and psychiatric examination organized by the Ministry of Family, War Veterans and Intergenerational Solidarity. Included were participants with status of either wife of war veteran suffering from PTSD, wife who lost her husband in war circumstances or wife of war veteran with physical disabilities resulting from war activities. All three groups were asked to fill out the World Health Organization Quality of Life Questionnaire - short form (WHOQOL-BREF). Results indicate that assumed intensity of secondary trauma is not associated with quality of life. Namely, the highest level of satisfaction was found in wives of the most seriously affected invalids of war (M=3.77; sd=0.741), folowed by the wives of deceased soldiers (M=3.5; sd= 0.697), while the lowest quality of life results were found in wives of veterans suffering from PTSD (M=3.12; sd=0.608). Our results confirm that, nearly 15 years after the war, wives of disabled or killed Croatian soldiers have a (comparatively) satisfactory quality of their everyday lives, compared to the wives of veterans suffering from PTSD.

  10. Rovibrational spectroscopy using a kinetic energy operator in Eckart frame and the multi-configuration time-dependent Hartree (MCTDH) approach

    SciTech Connect

    Sadri, Keyvan Meyer, Hans-Dieter; Lauvergnat, David; Gatti, Fabien

    2014-09-21

    For computational rovibrational spectroscopy the choice of the frame is critical for an approximate separation of overall rotation from internal motions. To minimize the coupling between internal coordinates and rotation, Eckart proposed a condition [“Some studies concerning rotating axes and polyatomic molecules,” Phys. Rev. 47, 552–558 (1935)] and a frame that fulfills this condition is hence called an Eckart frame. A method is developed to introduce in a systematic way the Eckart frame for the expression of the kinetic energy operator (KEO) in the polyspherical approach. The computed energy levels of a water molecule are compared with those obtained using a KEO in the standard definition of the Body-fixed frame of the polyspherical approach. The KEO in the Eckart frame leads to a faster convergence especially for large J states and vibrationally excited states. To provide an example with more degrees of freedom, rotational states of the vibrational ground state of the trans nitrous acid (HONO) are also investigated.

  11. Tick-Borne Encephalitis Virus Habitats in North East Germany: Reemergence of TBEV in Ticks after 15 Years of Inactivity

    PubMed Central

    Krienke, Anja; Riebold, Diana; Loebermann, Micha; Littmann, Martina; Fiedler, Karin; Klaus, Christine; Süss, Jochen; Reisinger, Emil Christian

    2014-01-01

    The incidence of tick-borne encephalitis has risen in Europe since 1990 and the tick-borne encephalitis virus (TBEV) has been documented to be spreading into regions where it was not previously endemic. In Mecklenburg-West Pomerania, a federal state in Northern Germany, TBEV was not detectable in over 16,000 collected ticks between 1992 and 2004. Until 2004, the last human case of TBE in the region was reported in 1985. Following the occurrence of three autochthonous human cases of TBE after 2004, however, we collected ticks from the areas in which the infections were contracted. To increase the chance of detecting TBEV-RNA, some of the ticks were fed on mice. Using nested RT-PCR, we were able to confirm the presence of TBEV in ticks for the first time after 15 years. A phylogenetic analysis revealed a close relationship between the sequences we obtained and a TBEV sequence from Mecklenburg-East Pomerania published in 1992 and pointed to the reemergence of a natural focus of TBEV after years of low activity. Our results imply that natural foci of TBEV may either persist at low levels of activity for years or reemerge through the agency of migrating birds. PMID:25110671

  12. Scoliosis screening results of primary school students (11-15 years old group) in the west side of Istanbul.

    PubMed

    Çolak, Tuğba Kuru; Apti, Adnan; Dereli, E Elçin; Özdinçler, Arzu Razak; Çolak, İlker

    2015-09-01

    [Purpose] The present study aimed to find out the scoliosis prevalence 11-15 years old children and to create awareness about scoliosis. [Subjects and Methods] All of the children were assessed using the Adams Forward Bendings Test and a scoliometer. Sagittal plane changes such as kyphosis, lordosis, hypokyphosis, hypolordosis and anterior head tilt were screened. Children with trunk rotation angles (ATR) of 4 degrees or more were suspected of having scoliosis, and were evaluated for a second time for gibbosity height, arm-trunk distance, and ATR. [Results] A total of 2,207 children were screened and the evaluation revealed there were 11 girls (0.49%) with a Cobb angle of 10 degrees and more. The maximum Cobb angle was 43° (right thoracic-left lumbar) and the maximum ATR was 12°. Two children had kyphosis and lordosis, and one had hypokyphosis and was diagnosed as having idiopathic scoliosis. [Conclusion] Families should regularly check their children, even if they are not diagnosed as having scoliosis in school screenings. It is our opinion that our study increased the awareness of the families about scoliosis by screening, brochures and posters. In the future, if school screenings were performed as a routine procedure and scoliotic students were followed over the long term, the actual effectiveness of screening would be able to be detected. PMID:26504296

  13. Lessons learnt from the 15 years experience of the French case in the field of HLLL waste

    SciTech Connect

    Ouzounian, G.

    2007-07-01

    Year 2006 has been marked in France by the vote in the Parliament of the Planning Act of 28 June, 2006, concerning the sustainable management of radioactive materials and waste. This vote was the achievement of a 15 years research programme performed as required by the previous Research Law of 1991, also known as the Bataille Law, from the name of Christian Bataille, MP, who drafted it and monitored its enforcement as a member of the Parliamentary Office for Scientific and Technological Assessment (Office Parlementaire d'Evaluation des Choix Scientifiques et Techniques - OPECST). At that time a stepwise approach to siting was introduced in the process. It included the study of several alternatives to the geological disposal of long lived high level radioactive waste. Those alternatives have been thoroughly studied and assessed before the Government decided to submit the bill to the Parliament. Experience has been gained not only on the scientific and technical aspects, but also in the field of decision making process, also called now governance. However, not only the results of the research programme were decisive in preparing the bill, but also of major importance were the industrial experience of ANDRA and the rigorous programme management along all those years. Main lessons learnt from the experience are given in this paper. (authors)

  14. Evaluation of the Effectiveness of the Stereotactic Body Frame in Reducing Respiratory Intrafractional Organ Motion Using the Real-Time Tumor-Tracking Radiotherapy System

    SciTech Connect

    Bengua, Gerard; Ishikawa, Masayori; Sutherland, Kenneth; Horita, Kenji; Yamazaki, Rie; Fujita, Katsuhisa; Onimaru, Rikiya; Katoh, Noriwo; Inoue, Tetsuya; Onodera, Shunsuke; Shirato, Hiroki

    2010-06-01

    Purpose: To evaluate the effectiveness of the stereotactic body frame (SBF), with or without a diaphragm press or a breathing cycle monitoring device (Abches), in controlling the range of lung tumor motion, by tracking the real-time position of fiducial markers. Methods and Materials: The trajectories of gold markers in the lung were tracked with the real-time tumor-tracking radiotherapy system. The SBF was used for patient immobilization and the diaphragm press and Abches were used to actively control breathing and for self-controlled respiration, respectively. Tracking was performed in five setups, with and without immobilization and respiration control. The results were evaluated using the effective range, which was defined as the range that includes 95% of all the recorded marker positions in each setup. Results: The SBF, with or without a diaphragm press or Abches, did not yield effective ranges of marker motion which were significantly different from setups that did not use these materials. The differences in the effective marker ranges in the upper lobes for all the patient setups were less than 1mm. Larger effective ranges were obtained for the markers in the middle or lower lobes. Conclusion: The effectiveness of controlling respiratory-induced organ motion by using the SBF+diaphragm press or SBF + Abches patient setups were highly dependent on the individual patient reaction to the use of these materials and the location of the markers. They may be considered for lung tumors in the lower lobes, but are not necessary for tumors in the upper lobes.

  15. Sudden, unexpected death of a 15-year-old boy due to pancarditis

    PubMed Central

    Osculati, Antonio; Visonà, Silvia Damiana; Ventura, Francesco; Castelli, Francesca; Andrello, Luisa

    2016-01-01

    Abstract Background: Generally, rheumatic heart disease is, today, sporadic in developed countries, even though it continues to be a major health hazard in the developing ones. It is also a very rare cause of sudden unexpected death. We report a case of a 15-year-old boy who suddenly died at home. Since 3 days he had presented fever and chest pain. The family physician had diagnosed bronchitis and treated the boy with amoxicillin. Methods: Seven hours after death, a forensic autopsy were performed . Before the autopsy, anamnesis and some circumstantial data were collected from the boy's parents. During the autopsy, samples for histological, toxicological and molecular examinations were collected. The samples for the histology (brain, hypophysis, heart and pericardium, lungs, spleen, liver, kidney, adrenal glands) were formalin fixed and paraffin embedded. Each section was stained with Hematoxylin-Eosin. Immunostaining was also performed, with anti-CD 68, anti-CD3, anti-CD 20, anti-myeloperoxidase. Microbiological cultures were performed on cardiac blood, myocardium, pericardial effusion and cerebrospinal fluid samples collected during autopsy. Blood specimens were also processed through PCR, in order to reveal the presence of Enteroviruses, Chickenpox virus, Epstein Barr virus. Also chemical-toxicological examinations for the detection of the main medications and drugs were performed on blood samples. Results: The anamnesis, collected before the autopsy, revealed an acute pharyngitis few weeks before. The autopsy, and the following histological and immunochemical examinations suggested an immunological etiology. The immunohistochemistry, showing a strong positivity of antiCD68 antibodies, integrated with clinical-anamnestic information, leads to hypothesize a rheumatic carditis. Conclusion: In light of this case, at least 3 main messages of great importance for the clinician can be deduced. First, an accurate anamnesis collected by the family physician could have

  16. Investigating earthquake scaling relationships from a 15 year archive of InSAR-derived earthquake models

    NASA Astrophysics Data System (ADS)

    Funning, G. J.; Ferreira, A. M.; Parsons, B. E.

    2008-12-01

    In the 15 years since the first InSAR study of the 1992 Landers earthquake, the first event to be studied using InSAR, over 50 events have been studied wholly or jointly using InSAR. This constitutes a rich archive of published studies that can be mined for information on earthquake phenomenology. Empirical earthquake scaling relationships, as can be inferred from estimates of fault dimensions, slip and moment for multiple earthquakes, are extensively used in seismic hazard forecasting, and also constitute a means of placing constraints on the bulk mechanical behaviour of the seismogenic upper crust. As a source of such data, studies that utilise information from InSAR have an advantage over seismic methods in that in many cases, a key parameter, the fault length, can be measured directly from the observations. In addition, in cases of good interferogram coherence, the high spatial density of surface deformation observations that InSAR affords can place tight constraints on fault width and other important parameters. We present here a preliminary survey of earthquake scaling relationships as supported by the existing archive of InSAR earthquake studies. We find that for events with Mw > 6, the data support moment scaling with the square of fault length, in keeping with the studies of Scholz and others, and imply proportionality between fault average slip and fault length. There are currently too few datapoints for great earthquakes (Mw > 8) to assess any proposed change in scaling for such events. Scatterplots of average slip versus fault length show two broad fields -- an area of high slip-to-length ratios (> 2 × 10-5) which are predominantly associated with faults with low long-term slip rates, predominantly from intraplate settings, and an area of lower slip-to-length ratios (< 2 × 10-5) which typically are larger events from faults with higher long-term slip rates (e.g. the North Anatolian and Kunlun faults, and the Peru-Chile subduction zone). In addition

  17. Copper-complexed catenanes and rotaxanes in motion: 15 years of molecular machines.

    PubMed

    Durot, Stéphanie; Reviriego, Felipe; Sauvage, Jean-Pierre

    2010-11-28

    In this review, we try to summarise the work performed in our laboratories in the course of the last 15 years, in the field of catenane- and rotaxane-based molecular machines containing copper(I), copper(II) or zinc(II) atoms. We put our work into perspective, showing how the properties of the compounds made have been gradually improved, mostly in terms of motion rate. In parallel, the function of the molecular machines elaborated have been made more and more complex. Instead of discussing all the systems elaborated and studied in our team, we preferred to select a few representative examples and show what were the principles which guided us for improving their performances and how the compounds were experimentally modified to afford new functions and faster-responding molecular machines. Starting from an electrochemically-driven "swinging" [2]catenane, reported in 1994, whose rearrangement was disappointingly slow, we could recently elaborate fast moving pirouetting copper-complexed [2]rotaxanes or molecular shuttles. The rearrangement mechanism of the pirouetting systems, as studied by experimental and computational methods, led us to synthesise interlocking compounds with a very open structure around the copper centre, allowing facile ligand exchange. With such compounds, whose copper centres are highly accessible, the minutes or hours required for the first generation of molecular machines to rearrange were converted to milliseconds or seconds, demonstrating that the rate limiting step in the electrochemically-steered copper catenanes and rotaxanes is probably decoordination of ligands to be replaced by entering ligands leading to the new form of the species. In addition to the electrochemically-piloted systems, we discuss a few compounds, which were not set in motion using an electrochemical signal but rather a chemical stimulus, including porphyrin-containing [2]rotaxanes or a "molecular muscle", based on a [2]rotaxane dimer of the hermaphroditic type. In

  18. Methods for Expanding Rotary Wing Aircraft Health and Usage Monitoring Systems to the Rotating Frame through Real-time Rotor Blade Kinematics Estimation

    NASA Astrophysics Data System (ADS)

    Allred, Charles Jefferson

    mechanism, similar to a Stewart Platform. A calibration method for this device is developed and the improved orientation estimation results are shown. The second method is not specific to the fully articulated rotor head mounting geometry of the first method. Rather, it utilizes micro-electromechanical (MEMS) accelerometers and gyroscopes configured to measure the centrifugal acceleration and rotation rate induced through rotor head rotation differentially. By measuring these quantities differentially, other accelerations from the fuselage reference frame are removed from the measurement, resulting in acceleration and rate quantities that are impacted only by the angle of the sensors relative to the plane of rotation. By mounting these sensors strategically and symmetrically about the rotor blade root center of rotation, the orientation of the rotor blade can be estimated in real time.

  19. Nutritional Transition in Children under Five Years and Women of Reproductive Age: A 15-Years Trend Analysis in Peru

    PubMed Central

    Loret de Mola, Christian; Quispe, Renato; Valle, Giancarlo A.; Poterico, Julio A.

    2014-01-01

    Background Rapid urbanization, increase in food availability, and changes in diet and lifestyle patterns have been changing nutritional profiles in developing nations. We aimed to describe nutritional changes in children under 5 years and women of reproductive age in Peru, during a 15-year period of rapid economic development and social policy enhancement. Materials and Methods Trend analyses of anthropometric measures in children of preschool age and women between 15–49 years, using the Peruvian National Demographic and Family Health Surveys (DHS) from 1996 to 2011. WHO growth curves were used to define stunting, underweight, wasting and overweight in children <5y. We employed the WHO BMI-age standardized curves for teenagers between 15–19y. In women >19 years, body mass index (BMI) was analyzed both categorically and as a continuous variable. To statistically analyze the trends, we used regression models: Linear and Poisson for continuous and binary outcomes, respectively. Results We analyzed data from 123 642 women and 64 135 children, from 1996 to 2011. Decreases over time were evidenced for underweight (p<0.001), wasting (p<0.001), and stunting (p<0.001) in children under 5y. This effect was particularly noted in urban settings. Overweight levels in children reduced (p<0.001), however this reduction stopped, in urban settings, since 2005 (∼12%). Anemia decreased in children and women (p<0.001); with higher reduction in urban (↓43%) than in rural children (↓24%). BMI in women aged 15–19 years increased (p<0.001) across time, with noticeable BMI-curve shift in women older than 30 years. Moreover, obesity doubled during this period in women more than 19y. Conclusion Nutrition transition in Peru shows different patterns for urban and rural populations. Public policies should emphasize targeting both malnutrition conditions—undernutrition/stunting, overweight/obesity and anemia—considering age and place of residence in rapid developing societies

  20. A Look into the National Drought Mitigation Center: Providing 15 Years of Drought Services (Invited)

    NASA Astrophysics Data System (ADS)

    Svoboda, M. D.; Hayes, M. J.; Knutson, C. L.; Wardlow, B. D.

    2009-12-01

    The National Drought Mitigation Center (NDMC) was formed in 1995 at the University of Nebraska-Lincoln. Over the past 15 years, the NDMC has made it a priority to work with various local, state, tribal and federal entities to provide a suite of drought/climate services, with a goal of bringing research to fruition through applications and operations. Through our research and outreach projects, the NDMC has worked to reduce risk to drought by developing several mitigation strategies, monitoring and decision making tools and other services aimed at enhancing our nation’s capacity to cope with drought. Two of the earliest NDMC activities were the creation of a website and assessing drought conditions around the United States. An electronic drought clearinghouse was built in 1995 at drought.unl.edu. The site was designed, and still concentrates, on the concepts of drought monitoring, planning, and mitigation and also serves as a repository of information from around the world. The NDMC’s electronic quarterly newsletter, DroughtScape, disseminates information about all things drought to people across the country. In addition, the NDMC has developed and is home to websites for the U.S. Drought Monitor (USDM), Drought Impact Reporter (DIR), and the Vegetation Drought Response Index (VegDRI). In an effort to inform decision makers, the NDMC continually pursues ways to raise the awareness and visibility of drought as one of the most costly hazards we face. This began in the mid-1990s with the creation of a state-based drought impact assessment map that would help lead to the formation of the USDM in 1999 and the DIR in 2005. The NDMC plays a key role in producing the weekly USDM and the monthly North American Drought Monitor (NADM). The USDM was created out of collaborations between the NDMC, United States Department of Agriculture (USDA) and National Oceanic and Atmospheric Administration (NOAA) and has quickly become one of the most widely used products in assessing

  1. VIRTUAL FRAME BUFFER INTERFACE

    NASA Technical Reports Server (NTRS)

    Wolfe, T. L.

    1994-01-01

    Large image processing systems use multiple frame buffers with differing architectures and vendor supplied user interfaces. This variety of architectures and interfaces creates software development, maintenance, and portability problems for application programs. The Virtual Frame Buffer Interface program makes all frame buffers appear as a generic frame buffer with a specified set of characteristics, allowing programmers to write code which will run unmodified on all supported hardware. The Virtual Frame Buffer Interface converts generic commands to actual device commands. The virtual frame buffer consists of a definition of capabilities and FORTRAN subroutines that are called by application programs. The virtual frame buffer routines may be treated as subroutines, logical functions, or integer functions by the application program. Routines are included that allocate and manage hardware resources such as frame buffers, monitors, video switches, trackballs, tablets and joysticks; access image memory planes; and perform alphanumeric font or text generation. The subroutines for the various "real" frame buffers are in separate VAX/VMS shared libraries allowing modification, correction or enhancement of the virtual interface without affecting application programs. The Virtual Frame Buffer Interface program was developed in FORTRAN 77 for a DEC VAX 11/780 or a DEC VAX 11/750 under VMS 4.X. It supports ADAGE IK3000, DEANZA IP8500, Low Resolution RAMTEK 9460, and High Resolution RAMTEK 9460 Frame Buffers. It has a central memory requirement of approximately 150K. This program was developed in 1985.

  2. Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia.

    PubMed

    Stipancic, Gordana; Sepec, Marija Pozgaj; Sabolic, Lavinija La Grasta; Radica, Ana; Skrabic, Veselin; Severinski, Srecko; Tiljak, Mirjana Kujundzic

    2011-01-01

    The aim of the study was to determine the clinical and biochemical characteristics of type 1 diabetes mellitus (DM) at presentation in children younger than 15 years in Croatia during a 9-year period, with special attention to diabetic ketoacidosis (DKA) incidence. The registered data set comprised blood glucose, pH, serum bicarbonate levels, and clinical symptoms at disease manifestation. During the study period, 692 children were diagnosed with type 1 DM. Polydipsia (96.7%), polyuria (96.05%), and weight loss (82.7%) were the most frequent symptoms anticipating disease detection. Enuresis was recorded in 11.55%. A total of 36.41% patients had DKA (pH < 7.3) at disease onset. During the 9-year period, the percentage of children presenting with DKA at time of diagnosis decreased from 41.67% to 33.33% (z = 1.68, p = 0.046). A positive family history of DM, the only factor with an impact on the DKA incidence rate in our population, lowers the probability of the development of ketoacidosis. This study confirms the importance of the detection of the classic symptoms of polyuria, polydipsia, and weight loss in patients with new-onset type 1 DM. The percentage of patients with DKA at diabetes onset decreased during the observed period but is still high and includes one-third of all patients. This is why in every acutely ill child, especially at a younger age, one should evaluate the possibility of type 1 DM to avoid the development of ketoacidosis. PMID:22145453

  3. Online teaching and learning in oceanography: A look back at 15 years of undergraduate general education (Invited)

    NASA Astrophysics Data System (ADS)

    Reed, D.

    2013-12-01

    Online courses in higher education have garnered a growing presence in the popular media, yet misperceptions abound. Consequently, a retrospective examination of the evolution of an online oceanography class, first offered to undergraduates at the San Jose State University in the fall semester of 1998, may be especially relevant to the development of future efforts in this field. Since that initial offering, the development of the course, involving the creation of virtual field experiences whereby students take on the role of practicing research oceanographers, has been supported through several awards from the National Science Foundation, principally the Division of Undergraduate Education and the Geoscience Directorate. The online material, organized into expeditions, which focus on the nature of scientific discovery, has evolved over time from a static graphics and text-based format to include video, largely available through YouTube, and animations that take advantage of social media, all to highlight contemporary ocean research. To sustain the project beyond NSF funding, the course has been offered throughout the academic year, and in winter and summer special sessions, to more the 4000 students over the 15 year period since its initial offering. The materials have always been openly available through the course website (http://oceansjsu.com) to institutions throughout the world, long in advance of current MOOC movement. Just as the course format, and available content, have evolved, so have the students enrolled in the class, which now more closely mirror the university student body as a whole. Future efforts in course development should span multi-campus university systems to take advantage of the collective scientific expertise available and to leverage the effort across a larger number of courses and disciplines.

  4. Tackling malnutrition: a systematic review of 15-year research evidence from INDEPTH health and demographic surveillance systems

    PubMed Central

    Arthur, Samuelina S.; Nyide, Bongiwe; Soura, Abdramane Bassiahi; Kahn, Kathleen; Weston, Mark; Sankoh, Osman

    2015-01-01

    Background Nutrition is the intake of food in relation to the body's dietary needs. Malnutrition results from the intake of inadequate or excess food. This can lead to reduced immunity, increased susceptibility to disease, impaired physical and mental development, and reduced productivity. Objective To perform a systematic review to assess research conducted by the International Network for the Demographic Evaluation of Populations and their Health (INDEPTH) of health and demographic surveillance systems (HDSSs) over a 15-year period on malnutrition, its determinants, the effects of under and over nutrition, and intervention research on malnutrition in low- and middle-income countries (LMICs). Methods Relevant publication titles were uploaded onto the Zotero research tool from different databases (60% from PubMed). Using the keywords ‘nutrition’, ‘malnutrition’, ‘over and under nutrition’, we selected publications that were based only on data generated through the longitudinal HDSS platform. All titles and abstracts were screened to determine inclusion eligibility and full articles were independently assessed according to inclusion/exclusion criteria. For inclusion in this study, papers had to cover research on at least one of the following topics: the problem of malnutrition, its determinants, its effects, and intervention research on malnutrition. One hundred and forty eight papers were identified and reviewed, and 67 were selected for this study. Results The INDEPTH research identified rising levels of overweight and obesity, sometimes in the same settings as under-nutrition. Urbanisation appears to be protective against under-nutrition, but it heightens the risk of obesity. Appropriately timed breastfeeding interventions were protective against malnutrition. Conclusions Although INDEPTH has expanded the global knowledge base on nutrition, many questions remain unresolved. There is a need for more investment in nutrition research in LMICs in order to

  5. Evaluating Trends in Historical PM2.5 Element Concentrations by Reanalyzing a 15-Year Sample Archive

    NASA Astrophysics Data System (ADS)

    Hyslop, N. P.; White, W. H.; Trzepla, K.

    2014-12-01

    The IMPROVE (Interagency Monitoring of PROtected Visual Environments) network monitors aerosol concentrations at 170 remote sites throughout the United States. Twenty-four-hour filter samples of particulate matter are collected every third day and analyzed for chemical composition. About 30 of the sites have operated continuously since 1988, and the sustained data record (http://views.cira.colostate.edu/web/) offers a unique window on regional aerosol trends. All elemental analyses have been performed by Crocker Nuclear Laboratory at the University of California in Davis, and sample filters collected since 1995 are archived on campus. The suite of reported elements has remained constant, but the analytical methods employed for their determination have evolved. For example, the elements Na - Mn were determined by PIXE until November 2001, then by XRF analysis in a He-flushed atmosphere through 2004, and by XRF analysis in vacuum since January 2005. In addition to these fundamental changes, incompletely-documented operational factors such as detector performance and calibration details have introduced variations in the measurements. Because the past analytical methods were non-destructive, the archived filters can be re-analyzed with the current analytical systems and protocols. The 15-year sample archives from Great Smoky Mountains (GRSM), Mount Rainier (MORA), and Point Reyes National Parks (PORE) were selected for reanalysis. The agreement between the new analyses and original determinations varies with element and analytical era. The graph below compares the trend estimates for all the elements measured by IMPROVE based on the original and repeat analyses; the elements identified in color are measured above the detection limit more than 90% of the time. The trend estimates are sensitive to the treatment of non-detect data. The original and reanalysis trends are indistinguishable (have overlapping confidence intervals) for most of the well-detected elements.

  6. Is it possible and worth keeping track of deaths within general practice? Results of a 15 year observational study

    PubMed Central

    Beaumont, B; Hurwitz, B

    2003-01-01

    Aim: To assess the value of maintaining a death register in a general practice with particular reference to monitoring quality of care. Design of study: Observational study. Setting: Inner London general practice. Method: The practice maintained a manual death register, retained medical records of all deceased patients, and requested information on cause of death from health authorities and coroners for 15 years. Main outcome measures: Number and causes of deaths; 3 yearly age standardised death rates; proportion of deaths formally notified to the practice; place of death; source of cause of death information. Results: During the study period 578 patients died. Practice age standardised death rates fell significantly from 35.59 to 27.12/1000. 498 (86.2%) deaths were formally notified to the practice, 392 within 7 days of death. Of 143 deaths reported to the coroner, only 45 coroners' reports were received. 360 (64.1%) died in hospital, 139 (24.8%) at home, and 38 (6.8%) in a hospice. Death certificate cause of death information was obtained from patients' records in 33.6% (n=194) of cases and from health authority sources for 50% (n=289). The pattern of ascertained causes of deaths was similar to the national pattern. Conclusion: A death register can examine trends in practice deaths by age and place of death and comparisons undertaken with nationally published mortality data. An accurate picture of cause of death cannot be generated from routine data flows alone. There is delay in informing GPs of patient deaths. Meaningful and timely monitoring of deaths cannot be undertaken by individual practices. National Statistics should provide routine analysis of GP death certificate information. PMID:14532364

  7. Fatal Passenger Vehicle Crashes with At Least 1 Driver Younger than 15 Years: A Fatality Analysis Reporting System Study

    ERIC Educational Resources Information Center

    Frisch, Larry; Plessinger, Alexander

    2007-01-01

    Context: A small number of fatalities continue to occur due to motor vehicle crashes on highways in which at least 1 passenger vehicle (automobile, van, or small truck) is driven by a child younger than 15 years. Purpose: The purpose of this study was to extend previous work suggesting that such crashes occur frequently in the Southern states and…

  8. Proficiency Assessment of Male Volleyball Teams of the 13-15-Year Age Group at Estonian Championships

    ERIC Educational Resources Information Center

    Stamm, Meelis; Stamm, Raini; Koskel, Sade

    2008-01-01

    Study aim: Assessment of feasibility of using own computer software "Game" at competitions. Material and methods: The data were collected during Estonian championships in 2006 for male volleyball teams of the 13-15-years age group (n = 8). In all games, the performance of both teams was recorded in parallel with two computers. A total of 19 games…

  9. Health Behaviors and Protective Factors of School Students Aged 13-15 Years Old in Four Cities of China

    ERIC Educational Resources Information Center

    Tian, Benchun; Zhang, Wei; Qian, Ling; Lv, Shuhong; Tian, Xiangyang; Xiong, Guanglian; Yan, Weihong; Zhang, Xinwei; Kann, Laura K.; Riley, Leanne

    2007-01-01

    This paper presents baseline data on health behaviors and protective factors among junior middle school students aged 13-15 years old in China for the purpose of developing priorities, establishing programs and policies for school health and youth health and also establishing trends in the prevalence of these behaviors. The 2003 CHINA GSHS…

  10. The Relationship between Psychological Health and Attitude toward Christianity among Pupils Aged 11 to 15 Years in England

    ERIC Educational Resources Information Center

    Francis, Leslie J.; Burton, Linda

    2007-01-01

    Advocates of the secularization thesis describe radical decline in the significance of the Christian tradition among young people in England. In this context, a sample of 5,808 pupils age 11 to 15 years provided data about their religious identity and practice and completed the short-form Revised Junior Eysenck Personality Questionnaire (as a…

  11. Differential diagnosis of double site intussusception in childhood: a 15-year-old girl presenting with bowel obstruction.

    PubMed

    Davidson, Joseph; Wright, Naomi Jane; Kufeji, Dorothy

    2015-01-01

    Abdominal pain in a teenage girl is common; however, thorough history and examination can often distinguish a more rare or sinister diagnosis. We present a case of a 15-year-old girl presenting with abdominal pain, who was subsequently diagnosed with double intussusception secondary to her previously unrecognised Peutz-Jeghers syndrome (PJS). PMID:26581705

  12. Brief Screening Instrument of Posttraumatic Stress Disorder for Children and Adolescents 7-15 Years of Age

    ERIC Educational Resources Information Center

    Liu, AiZhong; Tan, Hongzhuan; Zhou, Jia; Li, Shuoqi; Yang, Tubao; Sun, Zhenqiu; Wen, Shi Wu

    2007-01-01

    The objective of this paper is to develop a brief screening instrument of posttraumatic stress disorder (PTSD) for young victims of natural disasters. Data were derived from flood victims in 1998 and 1999 in Hunan, China. A representative population sample of 6,852 subjects 7-15 years of age was selected. Among them, 6,073 (88.6%) were…

  13. The Campus Environmental Management System Cycle in Practice: 15 Years of Environmental Management, Education and Research at Dalhousie University

    ERIC Educational Resources Information Center

    Clarke, Amelia

    2006-01-01

    Purpose: To challenge the deliberate strategy approach of the environmental management system (EMS) cycle, and offer a model based on both the practical reality experienced at Dalhousie University and emergent strategy theory. Also, to share some of the lessons learned in the 15 years of environmental management at Dalhousie University.…

  14. Primary internal carotid artery aneurysm in a 15-year-old male: case report and review of the literature.

    PubMed

    Lopez, Daniel; Sarac, Timur; Lorenz, Robert

    2015-01-01

    Extracranial internal carotid artery aneurysms are a rare entity in the adult population. Very little information is known in the pediatric population. We present a case of a 15-year-old male with an isolated internal carotid artery aneurysm and a review of the literature.

  15. Individuality and Contextual Influences on Drug Dependence: A 15-Year Prospective Longitudinal Study of Adolescents from Harlem

    ERIC Educational Resources Information Center

    Brook, Judith S.; Lee, Jung Yeon; Brown, Elaine N.; Finch, Stephen J.; Brook, David W.

    2012-01-01

    In this 15-year longitudinal study the authors investigated individual and contextual factors that predispose adolescents from a disadvantaged urban area to drug dependence in adulthood. Adolescents were recruited from schools serving East Harlem in New York City. Of the 838 participants followed to adulthood, 59% were women, 55% were African…

  16. Financial Literacy of 15-Year-Olds: Results from PISA 2012. Data Point. NCES 2014-102

    ERIC Educational Resources Information Center

    Gonzales, Patrick; Kelly, Dana

    2014-01-01

    This Data Point uses data from the 2012 administration of the Program for International Student Assessment (PISA) financial literacy assessment. PISA is an international assessment that measures 15-year-old students' reading, mathematics, and science literacy and, in 2012, general problem solving and financial literacy. PISA is coordinated by…

  17. What Can Influence Students' Environmental Attitudes? Results from a Study of 15-Year-Old Students in France

    ERIC Educational Resources Information Center

    Le Hebel, Florence; Montpied, Pascale; Fontanieu, Valérie

    2014-01-01

    The purpose of this study is to investigate the environmental attitudes (EA) in the population of 15-year-old French students and, to check if the French student population presents similar EA categorization as described in the different models in the literature (e.g. the Model of Ecological Values, Wiseman & Bogner 2003). The second aim of…

  18. The Interest-Driven Pursuits of 15 Year Olds: "Sparks" and Their Association with Caring Relationships and Developmental Outcomes

    ERIC Educational Resources Information Center

    Ben-Eliyahu, Adar; Rhodes, Jean E.; Scales, Peter

    2014-01-01

    In this study, we examined the characteristics of adolescents' deep interests or "sparks," the role of relationships in supporting the development of sparks, and whether having a spark was associated with positive developmental outcomes. Participants included 1,860 15 years olds from across the United States who participated in the…

  19. Socratic Teaching Is Not Teaching, but Direct Transmission Is: Notes from 13 to 15-Year Olds' Conceptions of Teaching

    ERIC Educational Resources Information Center

    Tikva, Judith Bar

    2010-01-01

    We studied what 13-15-year-olds believe teaching's components are. Thirty-six children viewed two films: direct transmission (DT) and Socratic teaching (ST) and a third film of a non-teaching conversation (C). We investigated the participants' understanding of teaching's components and the role of intentionality in teaching. All children judged…

  20. Impact of Research Training Environment and Holland Personality Type: A 15-Year Follow-Up of Research Productivity

    ERIC Educational Resources Information Center

    Mallinckrodt, Brent; Gelso, Charles J.

    2002-01-01

    Ratings of the research training environment (RTE) and Holland personality type from 325 counseling psychology students who participated in G. M. Royalty, C. J. Gelso, B. Mallinckrodt, and K. Garrett's (1986) study were examined as predictors of the students' research productivity 15 years later. Graduates' research productivity was determined by…

  1. The Incentive Grant Approach in Higher Education: A 15 Year Record. Institute for Educational Leadership Reports: Nine.

    ERIC Educational Resources Information Center

    Finkelstein, Martin

    The incentive grant approach in higher Education is a resource allocation strategy that may have significant positive impact on educational performance. This document covers: (1) the incentive grant approach to resource allocation; (2) the evolution during the past 15 years of types of incentive grant programs and the contrasting roles played by…

  2. Facing the Future: A Focus on Mathematical Literacy among Australian 15-Year-Old Students in PISA 2003

    ERIC Educational Resources Information Center

    Thomson, Sue; Cresswell, John; De Bortoli, Lisa

    2004-01-01

    The Programme for International Student Assessment (PISA) is an initiative of the Organisation for Economic Co-operation and Development (OECD) in Paris. The overall aim of PISA is to measure how well 15-year-olds approaching the end of their compulsory schooling are prepared for meeting the challenges they will face in their lives beyond school.…

  3. Bone Mineral Content and Density Among Female NCAA Division I Athletes Across the Competitive Season and Over a Multi-Year Time Frame.

    PubMed

    Stanforth, Dixie; Lu, Tao; Stults-Kolehmainen, Matthew A; Crim, Brittany N; Stanforth, Philip R

    2016-10-01

    Stanforth, D, Lu, T, Stults-Kolehmainen, MA, Crim, BN, and Stanforth, PR. Bone mineral content and density among female NCAA Division I athletes across the competitive season and over a multi-year time frame. J Strength Cond Res 30(10): 2828-2838, 2016-Longitudinal and cross-sectional bone mineral content (BMC) and bone mineral density (BMD) comparisons were made among impact and nonimpact sports. Female collegiate athletes, 18-23 years of age, from basketball (BB; n = 38), soccer (SOC; n = 47), swimming (SW; n = 52), track sprinters and jumpers (TR; n = 49), and volleyball (VB; n = 26) had BMC/BMD measures preseason and postseason over 3 years. Control groups of 85 college females, 18-24 years of age, who completed 2 tests 1-3 years apart and of 170 college females, 18-20 years of age, were used for the longitudinal and cross-sectional analyses, respectively. A restricted maximum likelihood linear mixed model regression analysis with a compound symmetric heterogeneous variance-covariance matrix structure was used for all analyses (p ≤ 0.05). Increases from year-1 preseason to year-3 postseason included the following: total BMC (3.3%), total BMD (1.4%), and spine BMD (4.5%) for BB; total BMC (1.5%) and leg BMD (1.2%) for SOC; arm (1.8%), leg (1.9%), and total BMD (5.7%) for SW; total BMC (2.0%), arm (1.7%), leg (2.3%), pelvis (3.4%), spine (6.0%), and total BMD (2.3%) for TR; and arm (4.1%), leg (2.0%), pelvis (2.0%), spine (2.0%), and total BMD (2.7%) for VB. Comparisons among sports determined that BB had higher BMC and BMD values than all other sports for all variables except spine and total BMD; BB, SOC, TR, and VB had higher total BMC (11-29%), leg BMD (13-20%), and total BMD (9-15%) than SW and CON, and there were few differences among SOC, TR, and VB. In conclusion, small, significant increases in many BMC and BMD measures occur during female athlete's collegiate careers. The BMC and BMD differences between impact and nonimpact sports are large compared

  4. HLW Return from France to Germany - 15 Years of Experience in Public Acceptance and Technical Aspects - 12149

    SciTech Connect

    Graf, Wilhelm

    2012-07-01

    Germany over the whole 15-year long project running time could be faced efficiently. It has to be concluded that despite of all problems the anti-nuclear activities have caused so far, all transports of vitrified HLW have always been completed successfully by adapting the commonly established safety, security and public acceptance measures to the special conditions and needs in Germany and coordinating the activities of all parties involved but at the expense of high costs for industry and government and a challenging operational complexity. Apart from an anticipatory project planning a good communication between all involved industrial parties and the French and the German government was the key to the effective management of such shipments and to minimize the radiological, economic, environmental, public and political impact. The future will show how efficiently the gained experience can be used for further return projects which are to be realized since no reprocessed waste has yet been returned from UK and neither the medium-level nor the low-level radioactive waste has been transferred from France to Germany. (author)

  5. 29 CFR 570.35 - Hours of work and conditions of employment permitted for minors 14 and 15 years of age.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... minors 14 and 15 years of age. 570.35 Section 570.35 Labor Regulations Relating to Labor (Continued) WAGE... and conditions of employment permitted for minors 14 and 15 years of age. (a) Hours standards. Except... provided, for any youth 14 or 15 years of age who: (i) Has graduated from high school; (ii) Has...

  6. 29 CFR 570.35 - Hours of work and conditions of employment permitted for minors 14 and 15 years of age.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... minors 14 and 15 years of age. 570.35 Section 570.35 Labor Regulations Relating to Labor (Continued) WAGE... and conditions of employment permitted for minors 14 and 15 years of age. (a) Hours standards. Except... provided, for any youth 14 or 15 years of age who: (i) Has graduated from high school; (ii) Has...

  7. 29 CFR 570.35 - Hours of work and conditions of employment permitted for minors 14 and 15 years of age.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... minors 14 and 15 years of age. 570.35 Section 570.35 Labor Regulations Relating to Labor (Continued) WAGE... and conditions of employment permitted for minors 14 and 15 years of age. (a) Hours standards. Except... provided, for any youth 14 or 15 years of age who: (i) Has graduated from high school; (ii) Has...

  8. 29 CFR 570.35 - Hours of work and conditions of employment permitted for minors 14 and 15 years of age.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... minors 14 and 15 years of age. 570.35 Section 570.35 Labor Regulations Relating to Labor (Continued) WAGE... and conditions of employment permitted for minors 14 and 15 years of age. (a) Hours standards. Except... provided, for any youth 14 or 15 years of age who: (i) Has graduated from high school; (ii) Has...

  9. Impact of Cryoglobulinemic Syndrome on the Outcome of Chronic Hepatitis C Virus Infection: A 15-Year Prospective Study.

    PubMed

    Lauletta, Gianfranco; Russi, Sabino; Conteduca, Vincenza; Sansonno, Loredana; Dammacco, Franco; Sansonno, Domenico

    2013-08-26

    We evaluated the influence of cryoglobulinemic syndrome (CS) on the outcome of chronic hepatitis C virus (HCV) infection in a 15-year prospective study. We assessed a cohort of 950 chronically HCV-infected patients, collected from the beginning of 1990 to the end of 2010. All patients had received a liver histologic diagnosis. Mixed cryoglobulinemia (MC) was determined in 246 patients (25.8%), of whom 184 also had CS. They were assessed every 3 months for 15 years, at least; 141 patients with CS and 601 without MC completed the study.No spontaneous clearance of cryoglobulins was noted. Type II to type III spontaneous switching was ascertained in 1.6% (0.08%/yr) patients. The estimated progression rate of liver fibrosis was lower in CS(+) than in MC(-) patients (p < 0.05). The 15-year cumulative probability of developing cirrhosis and/or hepatocellular carcinoma was higher in MC(-) than in CS(+) patients (24.9% vs. 14.2%, p < 0.005 and 20.3% vs. 7.5%, p = 0.003, respectively). Renal insufficiency, neurologic impairment, or B-cell non-Hodgkin lymphoma were significantly more frequent in CS(+) than in MC(-) patients (32.6% vs. 3%, p < 0.0001; 31.2% vs. 4.8%, p < 0.0001; and 15% vs. 7.1%, p = 0.003, respectively). However, in spite of different morbidity features and causes of death, the 15-year survival rate was similar in the 2 groups (70.2% vs. 71.7%). Antiviral therapy had an undisputable impact on patient outcome.This 15-year prospective cohort study shows that, although CS has no influence on the overall survival of HCV-infected patients, it significantly modifies the natural history of chronically HCV-infected patients.

  10. Mental health inequalities in Slovenian 15-year-old adolescents explained by personal social position and family socioeconomic status

    PubMed Central

    2014-01-01

    Introduction Mental health inequalities are an increasingly important global problem. This study examined the association between mental health status and certain socioeconomic indicators (personal social position and the socioeconomic status of the family) in Slovenian 15-year-old adolescents. Methods Data originate from the WHO-Collaborative cross-national ‘Health Behavior in School-aged Children’ study conducted in Slovenia in 2010 (1,815 secondary school pupils, aged 15). Mental health status was measured by: KIDSCREEN-10, the Strength and Difficulties questionnaire (SDQ), a life satisfaction scale, and one question about feelings of depression. Socioeconomic position was measured by the socioeconomic status of the family (Family Affluence Scale, perceived material welfare, family type, occupational status of parents) and personal social position (number of friends and the type of school). Logistic regression and a multivariate analysis of variance (MANOVA) were performed. Results Girls had 2.5-times higher odds of suffering feelings of depression (p < 0.001), 1.5-times higher odds of low life satisfaction (p = 0.008), and a greater chance of a lower quality of life and a higher SDQ score than boys (p = 0.001). The adolescents who perceived their family’s material welfare as worse had 4-times higher odds (p < 0.001) of a low life satisfaction, a greater chance of a low quality of life, and a higher SDQ score than those who perceived it as better (p < 0.001). Adolescents with no friends had lower KIDSCREEN-10 and higher SDQ scores than those who had more than three friends. Conclusions Despite the fact that Slovenia is among the EU members with the lowest rates of social inequalities, it was found that adolescents with a lower socioeconomic position have poorer mental health than those with a higher socioeconomic position. Because of the financial crisis, we can expect an increase in social inequalities and a greater impact on

  11. 15-year incidence of diabetic ketoacidosis at onset of type 1 diabetes in children from a regional setting (Auckland, New Zealand)

    PubMed Central

    Jefferies, Craig; Cutfield, Samuel W.; Derraik, José G. B.; Bhagvandas, Jignal; Albert, Benjamin B.; Hofman, Paul L.; Gunn, Alistair J.; Cutfield, Wayne S.

    2015-01-01

    We assessed the incidence of diabetic ketoacidosis (DKA) in children aged <15 years with newly diagnosed type 1 diabetes mellitus (T1DM) in the Auckland Region (New Zealand) in 1999–2013, in a retrospective review of a complete regional cohort. DKA and its severity were classified according to ISPAD 2014 guidelines. Of 730 children presenting with new-onset T1DM over the 15-year time period, 195 cases had DKA of any severity (27%). There was no change in the incidence of DKA or the proportion of children with severe DKA at presentation. The incidence of DKA among children aged <2.0 years (n = 40) was 53% compared to 25% for those aged 2–14 years (n = 690; p = 0.005). In children aged 2–14 years, increasing age at diagnosis was associated with greater likelihood of DKA at presentation (p = 0.025), with the odds of DKA increasing 1.06 times with each year increase in age. Non-Europeans were more likely to present in DKA than New Zealand Europeans (OR 1.52; p = 0.048). Despite a consistent secular trend of increasing incidence of T1DM, there was no reduction in the incidence of DKA in new-onset T1DM in the Auckland Region over time. Thus, it is important to explore ways to reduce DKA risk. PMID:25989414

  12. 15-year incidence of diabetic ketoacidosis at onset of type 1 diabetes in children from a regional setting (Auckland, New Zealand).

    PubMed

    Jefferies, Craig; Cutfield, Samuel W; Derraik, José G B; Bhagvandas, Jignal; Albert, Benjamin B; Hofman, Paul L; Gunn, Alistair J; Cutfield, Wayne S

    2015-05-19

    We assessed the incidence of diabetic ketoacidosis (DKA) in children aged <15 years with newly diagnosed type 1 diabetes mellitus (T1DM) in the Auckland Region (New Zealand) in 1999-2013, in a retrospective review of a complete regional cohort. DKA and its severity were classified according to ISPAD 2014 guidelines. Of 730 children presenting with new-onset T1DM over the 15-year time period, 195 cases had DKA of any severity (27%). There was no change in the incidence of DKA or the proportion of children with severe DKA at presentation. The incidence of DKA among children aged <2.0 years (n = 40) was 53% compared to 25% for those aged 2-14 years (n = 690; p = 0.005). In children aged 2-14 years, increasing age at diagnosis was associated with greater likelihood of DKA at presentation (p = 0.025), with the odds of DKA increasing 1.06 times with each year increase in age. Non-Europeans were more likely to present in DKA than New Zealand Europeans (OR 1.52; p = 0.048). Despite a consistent secular trend of increasing incidence of T1DM, there was no reduction in the incidence of DKA in new-onset T1DM in the Auckland Region over time. Thus, it is important to explore ways to reduce DKA risk.

  13. Time dependent three-dimensional body frame quantal wave packet treatment of the H + H2 exchange reaction on the Liu-Siegbahn-Truhlar-Horowitz (LSTH) surface

    NASA Technical Reports Server (NTRS)

    Neuhauser, Daniel; Baer, Michael; Judson, Richard S.; Kouri, Donald J.

    1989-01-01

    The first successful application of the three-dimensional quantum body frame wave packet approach to reactive scattering is reported for the H + H2 exchange reaction on the LSTH potential surface. The method used is based on a procedure for calculating total reaction probabilities from wave packets. It is found that converged, vibrationally resolved reactive probabilities can be calculated with a grid that is not much larger than required for the pure inelastic calculation. Tabular results are presented for several energies.

  14. Frame independent cosmological perturbations

    SciTech Connect

    Prokopec, Tomislav; Weenink, Jan E-mail: j.g.weenink@uu.nl

    2013-09-01

    We compute the third order gauge invariant action for scalar-graviton interactions in the Jordan frame. We demonstrate that the gauge invariant action for scalar and tensor perturbations on one physical hypersurface only differs from that on another physical hypersurface via terms proportional to the equation of motion and boundary terms, such that the evolution of non-Gaussianity may be called unique. Moreover, we demonstrate that the gauge invariant curvature perturbation and graviton on uniform field hypersurfaces in the Jordan frame are equal to their counterparts in the Einstein frame. These frame independent perturbations are therefore particularly useful in relating results in different frames at the perturbative level. On the other hand, the field perturbation and graviton on uniform curvature hypersurfaces in the Jordan and Einstein frame are non-linearly related, as are their corresponding actions and n-point functions.

  15. Frame Rate and Human Vision

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.

    2012-01-01

    To enhance the quality of the theatre experience, the film industry is interested in achieving higher frame rates for capture and display. In this talk I will describe the basic spatio-temporal sensitivities of human vision, and how they respond to the time sequence of static images that is fundamental to cinematic presentation.

  16. Should Women Younger Than 40 Years of Age With Invasive Breast Cancer Have a Mastectomy?: 15-Year Outcomes in a Population-Based Cohort

    SciTech Connect

    Cao, Jeffrey Q.; Truong, Pauline T.; Olivotto, Ivo A.; Olson, Robert; Coulombe, Genevieve; Keyes, Mira; Weir, Lorna; Gelmon, Karen; Bernstein, Vanessa; Woods, Ryan; Speers, Caroline; Tyldesley, Scott

    2014-11-01

    Purpose: Optimal local management for young women with early-stage breast cancer remains controversial. This study examined 15-year outcomes among women younger than 40 years treated with breast-conserving surgery plus whole-breast radiation therapy (BCT) compared with those treated with modified radical mastectomy (MRM). Methods and Materials: Women aged 20 to 39 years with early-stage breast cancer diagnosed between 1989 and 2003 were identified in a population-based database. Primary outcomes of breast cancer–specific survival (BCSS), overall survival (OS) and secondary outcomes of local relapse–free survival (LRFS), locoregional relapse–free survival (LRRFS), and distant relapse–free survival (DRFS) were calculated using Kaplan-Meier methods and compared between BCT and MRM cohorts using log-rank tests. A planned subgroup analysis was performed on patients considered “ideal” for BCT (ie, T1N0, negative margins and no extensive ductal carcinoma in situ) and in whom local therapy may have the largest impact on survival because of low systemic risk. Results: 965 patients were identified; 616 had BCT and 349 had MRM. The median follow-up time was 14.4 years (range, 8.4-23.3 years). Overall, 15-year rates of BCSS (76.0% vs 74.1%, P=.62), OS (74.2% vs 73.0%, P=.75), LRFS (85.4% vs 86.5%, P=.95), LRRFS (82.2% vs 81.6%, P=.61), and DRFS (74.4% vs 71.6%, P=.40) were similar between the BCT and MRM cohorts. In the “ideal” for BCT subgroup, there were 219 BCT and 67 MRM patients with a median follow-up time of 15.5 years. The 15-year BCSS (86.1% vs 82.9%, P=.57), OS (82.6% vs 82.9%, P=.89), LRFS (86.2% vs 84.2%, P=.50), LRRFS (83.1% vs 78.3%, P=.24), and DRFS (84.8% vs 79.1%, P=.17) were similar in the BCT and MRM cohorts. Conclusions: This population-based analysis with long-term follow-up confirmed that women younger than 40 years treated with BCT had similar 15-year outcomes compared with MRM. Young age alone is not a contraindication to BCT.

  17. Frame synchronization in PCM telemetry.

    NASA Technical Reports Server (NTRS)

    Peavey, B.

    1971-01-01

    The frame synchronization performance characteristics are defined that can be measured under actual operating conditions. The frame synchronization process is explained, and test data on the performance of frame synchronizers and frame synchronization codes are presented. The application of frame synchronization methods in specific cases is considered in the light of code selection, frame length, and data recovery.

  18. Hyperbaric Oxygen Therapy in Branch Retinal Artery Occlusion in a 15-Year-Old Boy with Methylenetetrahydrofolate Reductase Mutation

    PubMed Central

    Kadayifcilar, Sibel; Eldem, Bora

    2015-01-01

    Purpose. To report the efficacy of hyperbaric oxygen (HBO) therapy in a case of branch retinal artery occlusion (BRAO) in a 15-year-old boy. Methods. We report a 15-year-old boy with sudden loss of vision due to BRAO. Examination included laboratory evaluation for systemic risk factors. Follow-up exams included visual acuity, fundus examination, fundus fluorescein angiography, and visual field testing. HBO therapy was employed for treatment. Results. Medical history was positive for isolated glucocorticoid deficiency. Laboratory evaluation disclosed hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) mutation. The visual acuity 0.05 at presentation improved to 0.8 after 20 days of HBO therapy. There was no change on visual fields. Conclusion. In this pediatric case, HBO therapy was useful in the treatment of BRAO. PMID:25722905

  19. Causes of Death in Children Aged < 15 Years in the Inner Mongolia Region of China, 2008-2012

    PubMed Central

    Wang, Ying; Du, Maolin; Hao, Zhihui; Zhang, Hairong; Zhang, Qing; Hao, Wenli; Xi, Lei; Sun, Juan

    2016-01-01

    The objective of our study was to identify the causes of death in children <15 years of age in Inner Mongolia and to examine the age-specific causes of death. Study data from 2008–2012 were obtained from the Death Registry System that is maintained by the Inner Mongolia Centers for Disease Control and Prevention. The mortality rate (per 100,000) for children <15 years of age was calculated and stratified by age in different years. We computed the proportion of age-specific causes of death for children <15 years that occurred between 2008 and 2012 across eight monitoring points in Inner Mongolia. We used a log-linear model to analyze the year and age effects on childhood mortality. From 2008-2012, the standardized mortality of children <15 years of age was 42.78/100,000. The mortality rate was not significantly different from 2008 to 2012 (p>0.05); the mortality rate was the highest in the <1-year age group (p<0.05); and the mortality rate of the <1-year age group was higher in 2012 compared to that in 2009 (p<0.05), 2010 (p<0.05), and 2011 (p<0.05). In children aged 1-14 years, the leading cause of death was injuries, among which transport accident injuries were the most prevalent. To reduce the childhood mortality rate in Inner Mongolia, China, we should focus on the prevention of perinatal deaths in infants <1 year of age and on the prevention of transport accident injuries among older children (1-14 years). PMID:27157187

  20. Modern Steel Framed Schools.

    ERIC Educational Resources Information Center

    American Inst. of Steel Construction, Inc., New York, NY.

    In view of the cost of structural framing for school buildings, ten steel-framed schools are examined to review the economical advantages of steel for school construction. These schools do not resemble each other in size, shape, arrangement or unit cost; some are original in concept and architecture, and others are conservative. Cost and…

  1. The Landscape of Inappropriate Laboratory Testing: A 15-Year Meta-Analysis

    PubMed Central

    Zhi, Ming; Ding, Eric L.; Theisen-Toupal, Jesse; Whelan, Julia; Arnaout, Ramy

    2013-01-01

    Background Laboratory testing is the single highest-volume medical activity and drives clinical decision-making across medicine. However, the overall landscape of inappropriate testing, which is thought to be dominated by repeat testing, is unclear. Systematic differences in initial vs. repeat testing, measurement criteria, and other factors would suggest new priorities for improving laboratory testing. Methods A multi-database systematic review was performed on published studies from 1997–2012 using strict inclusion and exclusion criteria. Over- vs. underutilization, initial vs. repeat testing, low- vs. high-volume testing, subjective vs. objective appropriateness criteria, and restrictive vs. permissive appropriateness criteria, among other factors, were assessed. Results Overall mean rates of over- and underutilization were 20.6% (95% CI 16.2–24.9%) and 44.8% (95% CI 33.8–55.8%). Overutilization during initial testing (43.9%; 95% CI 35.4–52.5%) was six times higher than during repeat testing (7.4%; 95% CI 2.5–12.3%; P for stratum difference <0.001). Overutilization of low-volume tests (32.2%; 95% CI 25.0–39.4%) was three times that of high-volume tests (10.2%; 95% CI 2.6–17.7%; P<0.001). Overutilization measured according to restrictive criteria (44.2%; 95% CI 36.8–51.6%) was three times higher than for permissive criteria (12.0%; 95% CI 8.0–16.0%; P<0.001). Overutilization measured using subjective criteria (29.0%; 95% CI 21.9–36.1%) was nearly twice as high as for objective criteria (16.1%; 95% CI 11.0–21.2%; P = 0.004). Together, these factors explained over half (54%) of the overall variability in overutilization. There were no statistically significant differences between studies from the United States vs. elsewhere (P = 0.38) or among chemistry, hematology, microbiology, and molecular tests (P = 0.05–0.65) and no robust statistically significant trends over time. Conclusions The landscape of overutilization varies

  2. A 15-Year Longitudinal Analysis of Trends in Elective Urological Surgery – An Evidence Base for Modernising Medical Careers

    PubMed Central

    Nathaniel, C; Sangar, VK; Payne, SR

    2007-01-01

    INTRODUCTION The impact of Modernising Medical Careers on the differential need for consultant urologists and urological surgeons is as yet unknown. This study's aim was to determine what changes there had been in operative urological activity so as to predict the need for urological surgeons in the future. MATERIALS AND METHODS A retrospective study of all elective operative urological surgery over a 15-year period was performed. The absolute numbers of patients presenting for different grades of surgery were aggregated and analysed using the Spearman's rank correlation test. RESULTS Aggregated data from 27,839 procedures demonstrated no change in the number of operations (r 0.01; NS) or the number of diagnostic endoscopic procedures (r 0.21; NS) carried out over the study period. There was a decrease in endoscopic surgery related to a 70% reduction in trans-urethral resection of the prostate (TURP) (r −0.89; P = <0.0001) and an increase in ureteroscopic interventions (r 0.82; P = 0.0002) for stone disease. There was no change in the amount of major surgery carried out (r −0.43; NS) over the 15 years. CONCLUSIONS There have been changes to the pattern of surgery urologists have provided over the last 15 years but the need for complex surgical interventions has not altered. This suggests there will be as great a need for operating surgeons in the future, as currently exists. PMID:17346412

  3. The NICHD neonatal research network: changes in practice and outcomes during the first 15 years.

    PubMed

    Fanaroff, Avroy A; Hack, Maureen; Walsh, Michele C

    2003-08-01

    The National Institute of Child Health and Human Development (NICHD) Neonatal Research Network was founded in 1986 to perform trials that, because of their size and complexity, were beyond the scope of a single center and required the expertise and resources of many collaborating centers. This report briefly documents changes in mortality, selected morbidities, and therapies amongst Network centers. The Network registry incorporating perinatal and neonatal data on all infants with a birth weight 501-1500 g cared for at participating centers served as the database. Mortality and selected morbidities were compared for 3 time periods, 1987/1988, (7 centers 1,765 infants, presurfactant); 1993/1994 (12 centers, 4,593 infants, postsurfactant and moderate antenatal corticosteroid utilization); and 1999/2000 (15 centers, 5,848 infants, postsurfactant and widespread corticosteroid use). Detailed outcomes for infants with birth weights between 501 and 800 g, and gestational ages of 23 to 25 weeks are also presented because they dramatically document the changes over time. Mortality for the entire cohort decreased from 23% in 1987/1988 to 17% in 1993/1994 and 14% in 1999/2000. Between 1987/1988 and 1999/2000 mortality prior to discharge, decreased from 66% to 45% for infants weighing 501-750 g; from 34% to 12% for birth weight between 751 to 1000 g, and from 13% to 7% for infants between 1001 and 1500 g. Mortality was higher in boys. Survival free of major morbidity (chronic lung disease/bronchopulmonary dysplasia, necrotizing enterocolitis or grade III/IV intraventricular hemorrhage) did not change significantly over time. Since the inception of the Network, multiple births have increased from 18% to 26%; deliveries by Cesarean section from 47% to 57%, and antenatal corticosteroid use increased from 16% to 79%. Surfactant, which was not used prior to 1990, is now given to 57% of the infants, including 87% with birth weights between 501 and 750 g. There have been significant

  4. Exploring the Planet Mercury: 1.5 Years of MESSENGER Orbital Observations

    NASA Astrophysics Data System (ADS)

    Solomon, Sean C.; Nittler, L. R.; McNutt, R. L., Jr.

    2012-10-01

    Launched in 2004, MESSENGER flew by Mercury three times in 2008-2009 en route to becoming the first spacecraft to orbit the solar system’s innermost planet in March 2011. MESSENGER’s chemical remote sensing measurements of Mercury’s surface indicate that the planet’s bulk silicate fraction, low in Fe and high in Mg, differs from those of the other inner planets. Moreover, surface materials are richer in the moderately volatile constituents S and K than predicted by most current models for inner planet formation. Global image mosaics and targeted high-resolution images reveal that Mercury experienced globally extensive volcanism, with large expanses of plains emplaced as flood lavas and widespread examples of pyroclastic deposits likely emplaced during explosive eruptions of volatile-bearing magmas. Bright deposits within impact craters host fresh-appearing, rimless depressions or hollows, often with high-reflectance interiors and halos and likely formed through processes involving the geologically recent loss of volatiles. The large-scale deformational history of Mercury, although dominated by near-global contractional deformation as first seen by Mariner 10, is more complex than first appreciated, with numerous examples of extensional deformation that accompanied impact crater and basin modification. Mercury’s magnetic field is dominantly dipolar, but the field is axially symmetric and equatorially asymmetric, a geometry that poses challenges to dynamo models for field generation. The interaction between the solar wind and Mercury’s magnetosphere, among the most dynamic in the solar system, serves both to replenish the exosphere and space weather the planet’s surface. Plasma ions of planetary origin are seen throughout the sampled volume of Mercury’s magnetosphere, with maxima in heavy-ion fluxes in the planet’s magnetic-cusp regions. Bursts of energetic electrons, seen at most local times, point to an efficient acceleration mechanism operating

  5. Teaching Global Change to Undergraduates at Universidad Nacional de Colombia for 15 years

    NASA Astrophysics Data System (ADS)

    Mesa, O. J.

    2015-12-01

    First let's describe the context. Approximately 80% of our students in Medellin major in engineering. In the National University system students can choose freely twenty percent of the credits. Their decisions are made taking into account various reasons. As far as we know the amount of work and the expected grades are factors besides the interest in the topics. Statistics show that there is an even distribution among complementary professional, cross-disciplinary and general interest courses. Plan B took the name from Lexter Brown book, which was the original inspiration and text. The program expanded with more in depth consideration to a general understanding of climate and climate change science, and to water and energy crises because they are close to my research area. But we consider other global change uses as well, including recycling, loss of biodiversity, food crises, economics of climate change and demographic and social issues. We developed a textbook whose title would translate as "Where is the Globe heading?" that refers to a usual saying during Christmas time in relation to candle balloons popular at that time of the year that children and teen-agers try to catch. The expression reflects the need for predictions, call for action, but also acknowledges that chance is a factor to consider. I believe it summarizes well the content of the course. The class meets in a large auditorium with 250 sits. We moved from the usual size room of about 50 because of the large demand during registration. This forced us to adjust the methodology, but our evaluation is that such a large audience is worthwhile. Student's feedbacks at the end of the semester confirm this with very good rating and general comments. Besides crude diagnostics of the problems based on data and science we always make an effort to present solutions. For instance there is ample consideration to renewal energy technologies. Globalization is also a theme of the course, there are local actions but

  6. 15-Year biochemical relapse free survival in clinical Stage T1-T3 prostate cancer following combined external beam radiotherapy and brachytherapy; Seattle experience

    SciTech Connect

    Sylvester, John E. . E-mail: johnsylvester@seattleprostate.com; Grimm, Peter D.; Blasko, John C.; Millar, Jeremy; Orio, Peter F.; Skoglund, Scott; Galbreath, Robert W.; Merrick, Gregory

    2007-01-01

    Purpose: Long-term biochemical relapse-free survival (BRFS) rates in patients with clinical Stages T1-T3 prostate cancer continue to be scrutinized after treatment with external beam radiation therapy and brachytherapy. Methods and Materials: We report 15-year BRFS rates on 223 patients with clinically localized prostate cancer that were consecutively treated with I{sup 125} or Pd {sup 103} brachytherapy after 45-Gy neoadjuvant EBRT. Multivariate regression analysis was used to create a pretreatment clinical prognostic risk model using a modified American Society for Therapeutic Radiology and Oncology consensus definition (two consecutive serum prostate-specific antigen rises) as the outcome. Gleason scoring was performed by the pathologists at a community hospital. Time to biochemical failure was calculated and compared by using Kaplan-Meier plots. Results: Fifteen-year BRFS for the entire treatment group was 74%. BRFS using the Memorial Sloan-Kettering risk cohort analysis (95% confidence interval): low risk, 88%, intermediate risk 80%, and high risk 53%. Grouping by the risk classification described by D'Amico, the BRFS was: low risk 85.8%, intermediate risk 80.3%, and high risk 67.8% (p = 0.002). Conclusions: I{sup 125} or Pd{sup 103} brachytherapy combined with supplemental EBRT results in excellent 15-year biochemical control. Different risk group classification schemes lead to different BRFS results in the high-risk group cohorts.

  7. Risk factors for acute and overuse sport injuries in Swedish children 11 to 15 years old: What about resistance training with weights?

    PubMed

    Boström, A; Thulin, K; Fredriksson, M; Reese, D; Rockborn, P; Hammar, M L

    2016-03-01

    To determine the 1-year self-reported incidence of overuse and traumatic sport injuries and risk factors for injuries in children participating in a summer sports camp representing seven different sports. 4363 children, 11 to 15 years old participating in a summer camp in seven different sports answered a questionnaire. Injury in this cross-sectional study was defined as a sport-related trauma or overload leading to pain and dysfunction preventing the person from participation in training or competition for at least 1 week. A number of risk factors for injury were investigated such as sex, age, number of hours spent on training in general, and on resistance training with weights. Nearly half [49%, 95% confidence interval (CI) 48-51%] of the participants had been injured as a result of participation in a sport during the preceding year, significantly more boys than girls (53%, 95% CI 50-55% vs 46%, 95% CI 43-48%; P < 0.001). Three factors contributed to increased incidence of sport injuries: age, sex, and resistance training with weights. Time spent on resistance training with weights was significantly associated with sport injuries in a logistic regression analysis. In children age 11 to 15 years, the risk of having a sport-related injury increased with age and occurred more often in boys than in girls. Weight training was the only modifiable risk factor that contributed to a significant increase in the incidence of sport injuries.

  8. Expansion of signal transduction by G proteins The second 15 years or so: From 3 to 16 α subunits plus βγ dimers

    PubMed Central

    Birnbaumer, Lutz

    2007-01-01

    The first 15 years, or so, brought the realization that there existed a G protein coupled signal transduction mechanism by which hormone receptors regulate adenylyl cyclases and the light receptor rhodopsin activates visual phosphodiesterase. Three G proteins, Gs, Gi and transducin (T) had been characterized as αβγ heterotrimers, and Gsα-GTP and Tα-GTP had been identified as the sigaling arms of Gs and T. These discoveries were made using classical biochemical approaches, and culminated in the purification of these G proteins. The second 15 years, or so, are the subject of the present review. This time coincided with the advent of powerful recombinant DNA techniques. Combined with the classical approaches, the field expanded the repertoire of G proteins from 3 to 16, discovered the superfamily of seven transmembrane G protein coupled receptors (GPCRs) – which is not addressed in this article – and uncovered an amazing repertoire of effector functions regulated not only by αGTP complexes but also by βγ dimers. Emphasis is placed in presenting how the field developed with the hope of conveying why many of the new findings were made. PMID:17258171

  9. Sprint Performance Changes and Determinants in Afro-Caribbean Adolescents Between 13 and 15 Years Old

    PubMed Central

    Copaver, Karine Babel; Hertogh, Claude; Hue, Olivier

    2012-01-01

    Afro-Caribbean sprinters often reach high performance levels at an early age. Adolescence is a time of morphological and physiological changes. This study was designed to analyze the evolution in parameters of short sprint performance during adolescence in Afro-Caribbean boys, especially the stride number/body height ratio (SN/BH), which is at the interface of technical and morphological factors. Seventy-one 13-year-old boys performed vertical jumps and short sprint races. The races were filmed with a view to determine stride variables. Anthropometric parameters were also measured. The same tests were performed two years later. Body height and SN/BH were the main predictors of sprint performance. The delta of performance was principally explained by stride length and stride number. Although deterioration in technical parameters was expected, the parameters related to body size and stride length were the main sprint performance predictors rather than explosive force. These results could be useful in developing tests to detect sprint potential in youth. PMID:23487285

  10. Results of distraction callus osteogenesis in hand and foot in Iran: A 15-year experience

    PubMed Central

    Forootan, Kamal Seyed; Forootan, Nazila Seyed; Lebaschi, Amir Hussein

    2015-01-01

    Background: Distraction osteogenesis (DS) is currently an important technique for lengthening shortened bones of the hand and foot. Authors report their experience in applying DS for various conditions of the hand and foot using a distractor that the senior author has designed. Materials and Methods: Records of patients who underwent DS for hand and foot conditions in a private clinic were retrieved between January 2001 and January 2015. Data concerning distraction, outcome, and complications were recorded. Results: There were 17 patients, 7 males, and 10 females with a total 24 distractions. The mean length gained was 21.2 mm (1.69) and the mean total treatment time was 198.58 (15.88) days. Overall, complications occurred in 9 (37.5%) distractions. Major complications occurred in 2 (8.33%) of distractions. Minor complications occurred in 7 (29.2%) distractions. Conclusion: DS is an effective modality for lengthening bones of the hand and feet for both traumatic and congenital conditions. Joint stiffness/contracture is an important complication following DS of the metatarsals. PMID:26487873

  11. Onsets and codas in 1.5-year-olds’ word recognition

    PubMed Central

    Swingley, Daniel

    2009-01-01

    Previous tests of toddlers’ phonological knowledge of familiar words using word recognition tasks have examined syllable onsets but not word-final consonants (codas). However, there are good reasons to suppose that children’s knowledge of coda consonants might be less complete than their knowledge of onset consonants. To test this hypothesis, the present study examined 14- to 21-month-old children’s knowledge of the phonological forms of familiar words by measuring their comprehension of correctly-pronounced and mispronounced instances of those words using a visual fixation task. Mispronunciations substituted onset or coda consonants. Adults were tested in the same task for comparison with children. Children and adults fixated named targets more upon hearing correct pronunciations than upon hearing mispronunciations, whether those mispronunciations involved the word’s initial or final consonant. In addition, detailed analysis of the timing of adults’ and children’s eye movements provided clear evidence for incremental interpretation of the speech signal. Children’s responses were slower and less accurate overall, but children and adults showed nearly identical temporal effects of the placement of phonological substitutions. The results demonstrate accurate encoding of consonants even in words children cannot yet say. PMID:20126290

  12. Inequalities in Nutrition between Cambodian Women over the Last 15 Years (2000–2014)

    PubMed Central

    Greffeuille, Valérie; Sophonneary, Prak; Laillou, Arnaud; Gauthier, Ludovic; Hong, Rathmony; Hong, Rathavuth; Poirot, Etienne; Dijkhuizen, Marjoleine; Wieringa, Frank; Berger, Jacques

    2016-01-01

    This study aimed to describe the trends over four nationally representative Demographic Health Surveys (2000, 2005, 2010, and 2014) of the nutritional status of women of reproductive age in Cambodia and to assess the main factors of inequality with regards to nutrition. The prevalence of undernutrition and over-nutrition evolved in opposite trends from 2000 to 2014, with a significant decrease in underweight and a significant increase in overweight women. This results in a shift, with overweight prevalence in women being higher than underweight for the first time in 2014. Anemia was constantly high and still affected 45% of women in 2014. Multivariate analysis showed that age, wealth index, maternal education, number of children, year of survey, and anemia were contributing factors for being underweight. Being overweight was positively related to increase in age, wealth index, number of children, and year of survey; and negatively related to anemia and increase in education level. The risk of anemia was higher in the poorest households and for less-educated women and women living in rural areas. Consequently, policies should target the most vulnerable women, especially the youngest, and support integrated interventions in the health, social, and agriculture sectors to reduce inequalities in nutrition between women. PMID:27104556

  13. The 15 years of comet photometry: A comparative analysis of 80 comets

    NASA Technical Reports Server (NTRS)

    Osip, David J.; Schleicher, David G.; Millis, Robert L.; Ahearn, Michael F.; Birch, Peter V.

    1991-01-01

    In 1976, a program of narrowband photometry of comets was initiated that has encompassed well over 400 nights of observations. To date, the program has provided detailed information on 80 comets, 11 of which were observed during multiple apparitions. The filters (initially isolating CN, C2, and continuum and later including C3, OH, and NH) as well as the detectors used for the observations were changed over time, and the parameters adopted in the reduction and modeling of the data have likewise evolved. Accordingly, we have re-reduced the entire database and have derived production rates using current values for scalelengths and fluorescence efficiencies. Having completed this task, the results for different comets can now be meaningfully compared. The general characteristics that are discussed include ranges in composition (molecular production rate ratios) and dustiness (gas production compared with Af(rho)). Additionally an analysis of trends on how the production rates vary with heliocentric distance and on pre- and post-perihelion asymmetries in the production rates of individual comets. Possible taxonomic groupings are also described.

  14. Inequalities in Nutrition between Cambodian Women over the Last 15 Years (2000-2014).

    PubMed

    Greffeuille, Valérie; Sophonneary, Prak; Laillou, Arnaud; Gauthier, Ludovic; Hong, Rathmony; Hong, Rathavuth; Poirot, Etienne; Dijkhuizen, Marjoleine; Wieringa, Frank; Berger, Jacques

    2016-01-01

    This study aimed to describe the trends over four nationally representative Demographic Health Surveys (2000, 2005, 2010, and 2014) of the nutritional status of women of reproductive age in Cambodia and to assess the main factors of inequality with regards to nutrition. The prevalence of undernutrition and over-nutrition evolved in opposite trends from 2000 to 2014, with a significant decrease in underweight and a significant increase in overweight women. This results in a shift, with overweight prevalence in women being higher than underweight for the first time in 2014. Anemia was constantly high and still affected 45% of women in 2014. Multivariate analysis showed that age, wealth index, maternal education, number of children, year of survey, and anemia were contributing factors for being underweight. Being overweight was positively related to increase in age, wealth index, number of children, and year of survey; and negatively related to anemia and increase in education level. The risk of anemia was higher in the poorest households and for less-educated women and women living in rural areas. Consequently, policies should target the most vulnerable women, especially the youngest, and support integrated interventions in the health, social, and agriculture sectors to reduce inequalities in nutrition between women. PMID:27104556

  15. Changes in tobacco use among youths aged 13-15 years - Panama, 2002 and 2008.

    PubMed

    2009-01-01

    Tobacco use is the single most preventable cause of death in the world today, and the majority of smokers begin using tobacco products before age 18 years. However, before the late 1990s, few countries had reliable data on youth tobacco use. In 1999, the World Health Organization (WHO), CDC, and the Canadian Public Health Association developed the Global Youth Tobacco Survey (GYTS) to help countries monitor youth tobacco use. At the same time, WHO initiated the Framework Convention on Tobacco Control (WHO FCTC), the first international public health treaty on tobacco control. Panama ratified WHO FCTC in 2004 and enacted two key antitobacco regulations in 2005 and 2008. To evaluate progress toward attaining tobacco control goals in Panama, Panama's Ministry of Health, CDC, and WHO compared results from GYTS surveys conducted in Panama in 2002 and 2008. This report summarizes the results of that comparison, which revealed substantial decreases from 2002 to 2008 in youth current cigarette smoking (13.2% versus 4.3%), current use of tobacco products other than cigarettes (9.8% versus 5.8%), and likely initiation of smoking by never smokers (13.8% versus 10.0%). In addition, factors influencing tobacco use showed substantial decreases, including 1) exposure to secondhand smoke (SHS) at home and in public places, 2) best friends smoking, 3) protobacco advertising in newspapers and magazines, and 4) having an object with a tobacco company logo on it. These results suggest that comprehensive regulations in Panama helped reduce tobacco use among adolescents and further gains are possible. PMID:19129746

  16. Changes in tobacco use among youths aged 13-15 years - Panama, 2002 and 2008.

    PubMed

    2009-01-01

    Tobacco use is the single most preventable cause of death in the world today, and the majority of smokers begin using tobacco products before age 18 years. However, before the late 1990s, few countries had reliable data on youth tobacco use. In 1999, the World Health Organization (WHO), CDC, and the Canadian Public Health Association developed the Global Youth Tobacco Survey (GYTS) to help countries monitor youth tobacco use. At the same time, WHO initiated the Framework Convention on Tobacco Control (WHO FCTC), the first international public health treaty on tobacco control. Panama ratified WHO FCTC in 2004 and enacted two key antitobacco regulations in 2005 and 2008. To evaluate progress toward attaining tobacco control goals in Panama, Panama's Ministry of Health, CDC, and WHO compared results from GYTS surveys conducted in Panama in 2002 and 2008. This report summarizes the results of that comparison, which revealed substantial decreases from 2002 to 2008 in youth current cigarette smoking (13.2% versus 4.3%), current use of tobacco products other than cigarettes (9.8% versus 5.8%), and likely initiation of smoking by never smokers (13.8% versus 10.0%). In addition, factors influencing tobacco use showed substantial decreases, including 1) exposure to secondhand smoke (SHS) at home and in public places, 2) best friends smoking, 3) protobacco advertising in newspapers and magazines, and 4) having an object with a tobacco company logo on it. These results suggest that comprehensive regulations in Panama helped reduce tobacco use among adolescents and further gains are possible.

  17. 15 years of upper tropospheric relative humidity in-situ measurements by the MOZAIC programme

    NASA Astrophysics Data System (ADS)

    Neis, Patrick; Smit, Herman G. J.; Alteköster, Lukas; Rohs, Susanne; Wahner, Andreas; Spichtinger, Peter; Petzold, Andreas

    2015-04-01

    Water vapour is a major parameter in weather prediction and climate research. However, the interaction between water vapour in the upper troposphere and lowermost stratosphere (UT/LS) and tropopause dynamics are not well understood. Furthermore, the knowledge about potential trends and feedback mechanisms of upper troposphere/lower stratosphere water vapour is low because of the large variability of observations and relatively short data records. A continuous measurement of upper tropospheric humidity (UTH) is still difficult because the abundance of UTH is highly variable on spatial and temporal scales, which cannot be resolved, neither by the global radiosondes network nor by satellites. Since 1994, UTH data with high spatial and temporal resolution are provided by the in-situ measurements aboard civil passenger aircraft from the MOZAIC/IAGOS-programme (www.iagos.org). The measurement system is based on a capacitive hygrometer with a simultaneous temperature measurement installed in a conventional Rosemount housing. In recent studies the MOZAIC Capacitive Hygrometer (MCH) and its improved successor IAGOS Capacitive Hygrometer (ICH) are compared against research-grade water vapour instruments during airborne field studies. The qualification of the Capacitive Hygrometer for the use in long-term observation programmes is successfully demonstrated and the continuation of high data quality is confirmed for the transition from MCH to ICH. After the reanalysis of the relative humidity data from 1994 to 2009, this extensive and unique data set is examined by criteria of continuity, homogeneity and quantity of data coverage, to identify global regions suitable for UTH climatology and trend analyses. For the identified target regions time series and climatologies of, e.g., relative humidity with respect to ice, temperature, and absolute humidity are investigated. First results of this study will be presented.

  18. ESA's billion star surveyor - Flight operations experience from Gaia's first 1.5 Years

    NASA Astrophysics Data System (ADS)

    Milligan, D.; Rudolph, A.; Whitehead, G.; Loureiro, T.; Serpell, E.; di Marco, F.; Marie, J.; Ecale, E.

    2016-10-01

    This paper details the initial in-flight mission operations experience from ESA's ultra-precise Gaia spacecraft. Tasked with mapping the positions and movements of 1 billion stars to unprecedented precision (to the 10 s of micro-arc-second level, comparable to the width of a coin on the Moon as viewed from Earth). ESA's Science cornerstone mission is expected to also discover and chart 100,000's of new objects including near Earth Asteroids, exoplanets, brown dwarfs and Quasars. After a flawless launch 19 Dec 2013, Gaia was brought the circa 1.5 million kms into L2 via a sequence of technically demanding orbit transfer manoeuvres using onboard thrusters in thrust vectoring mode. Starting in parallel to this, and lasting 6 months, the full spacecraft was commissioned and brought gradually up to the highest operational mode. A number of problems were detected and tackled during commissioning and early routine phase operations. An apparent dimming of the on-board laser and imaged stars, was tracked down to water ice building up inside the telescope enclosure. Also apparent was more straylight than expected. Elsewhere, a micro-propulsion thruster developed unexpected performance levels and a back-up chemical thruster suffered a failed latch valve. These issues, like several others, were dealt with and solved in a series of review meetings, in-orbit special operations and newly developed procedures and on-board software changes. After commissioning Gaia was working so well that it was producing approximately 45% more science data than originally foreseen, primarily since it was able to see stars fainter than required. The mission operations concept was quickly adapted to partially automate ground operations and increase ground station time to allow the full scientific potential of Gaia to be realised.

  19. Cosmetic outcome 1-5 years after breast conservative surgery, irradiation and systemic therapy.

    PubMed

    Kelemen, Gyöngyi; Varga, Zoltán; Lázár, György; Thurzó, László; Kahán, Zsuzsanna

    2012-04-01

    The late side-effects of the local therapy of early breast cancer depend on many patient- and therapy-related parameters. We aimed at investigating the factors that influence the cosmetic and functional outcomes among our breast cancer patients after breast-conserving surgery and conformal radiotherapy, with or without adjuvant systemic therapy. A study was made of the association of the cosmetic outcome after a median follow-up time of 2.4 years and the clinical data on 198 patients extracted from a prospectively compiled database. Breast tenderness occurred more frequently among patients ≤50 years old (p < 0.05). Long-term side effects were related to radiotherapy-related factors the most, while no effect of the systemic therapy could be detected. The risk of hyperpigmentation, breast edema and breast fibrosis increased by 18%, 23% and 7%, respectively for every 100 cm(3) increase in the irradiated breast volume, while that of breast edema and breast fibrosis increased by 21% and 12%, respectively for every 10 cm(3) increase in the boost volume. Patients who received a photon boost were significantly more likely to develop breast edema and fibrosis than those who received electrons (p < 0.005). Dose inhomogeneity was related to the volume of the irradiated breast (p = 0.037). Dyspigmentation developed more often among patients older than 50 years, while smoking favoured both dyspigmentation and teleangiectasia. Breast edema was related to dyspigmentation (p = 0.003), fibrosis (p < 0.001) and breast asymmetry (p = 0.032), whereas none of these abnormalities were associated with teleangiectasia. Body image changes were more frequent at a younger age (p < 0.005), while the need to change clothing habits occurred more often at an older age (p < 0.05). Radiotherapy-related parameters appear to exert the greatest effect on the overall cosmetic outcome after breast-conserving surgery and postoperative radiotherapy.

  20. A 15-year global biogeochemical reanalysis with ocean colour data assimilation

    NASA Astrophysics Data System (ADS)

    Ford, David; Barciela, Rosa

    2013-04-01

    A continuous global time-series of remotely sensed ocean colour observations is available from 1997 to the present day. However coverage is incomplete, and limited to the sea surface. Models are therefore required to provide full spatial coverage, and to investigate the relationships between physical and biological variables and the carbon cycle. Data assimilation can then be used to constrain models to fit the observations, thereby combining the advantages of both sources of information. As part of the European Space Agency's Climate Change Initiative (ESA-CCI), we assimilate chlorophyll concentration derived from ocean colour observations into a coupled physical-biogeochemical model. The data assimilation scheme (Hemmings et al., 2008, J. Mar. Res.; Ford et al., 2012, Ocean Sci.) uses the information from the observations to update all biological and carbon cycle state variables within the model. Global daily reanalyses have been produced, with and without assimilation of merged ocean colour data provided by GlobColour, for the period September 1997 to August 2012. The assimilation has been shown to significantly improve the model's representation of chlorophyll concentration, at the surface and at depth. Furthermore, there is evidence of improvement to the representation of pCO2, nutrients and zooplankton concentration compared to in situ observations. We use the results to quantify recent seasonal and inter-annual variability in variables including chlorophyll concentration, air-sea CO2 flux and alkalinity. In particular, we explore the impact of physical drivers such as the El Niño Southern Oscillation (ENSO) on the model's representation of chlorophyll and the carbon cycle, and the pros and cons of the model reanalyses compared to observation-based climatologies. Furthermore, we perform a comparison between the GlobColour product and an initial version of a new merged product being developed as part of the ESA-CCI. Equivalent year-long hindcasts are

  1. Should Parents Allow Their Adolescent Children to Drink at Home? Family Factors as Predictors of Alcohol Involvement Trajectories Over 15 Years

    PubMed Central

    Levitt, Ash; Cooper, M. Lynne

    2015-01-01

    Objective: The present study examined familial risk and protective factors as moderators of parents allowing their adolescent children to drink at home on longitudinal alcohol involvement trajectories. Method: A total of 772 community adolescents and their parents provided data beginning in 1989 and at four subsequent time points over 15 years; Black adolescents were intentionally oversampled (50% at baseline). Results: Outcomes related to allowing adolescents to drink at home depended on family structure: Adolescents from intact families who were allowed to drink at home showed the lowest levels of alcohol use and problems over time, whereas those from nonintact families who were allowed to drink at home showed the highest levels of involvement. These results controlled for family history of alcohol problems, consistent parenting styles, and demographic characteristics. Conclusions: Results suggest that allowing adolescents to drink at home is neither inherently protective nor risky but depends on the family context. Implications for the development of adolescent alcohol involvement are discussed. PMID:26402346

  2. Real-time atomic-resolution imaging of crystal growth process in water by phase modulation atomic force microscopy at one frame per second

    SciTech Connect

    Miyata, Kazuki; Asakawa, Hitoshi; Fukuma, Takeshi

    2013-11-11

    Recent advancement in dynamic-mode atomic force microscopy (AFM) has enabled its operation in liquid with atomic-scale resolution. However, its imaging speed has often been too slow to visualize atomic-scale dynamic processes. Here, we propose a method for making a significant improvement in the operation speed of dynamic-mode AFM. In this method, we use a wideband and low-latency phase detector with an improved algorithm for the signal complexification. We demonstrate atomic-scale imaging of a calcite crystal growth process in water at one frame per second. The significant improvement in the imaging speed should enable various studies on unexplored atomic-scale interfacial processes.

  3. 10-15 years of GST monitoring over mountain permafrost in Switzerland: Indicators for driving forces for permafrost evolution

    NASA Astrophysics Data System (ADS)

    Staub, Benno; Delaloye, Reynald; Hilbich, Christin; Lambiel, Christophe; Nötzli, Jeannette; Völksch, Ingo

    2013-04-01

    different landform types (e.g. debris mantled terrain, talus slopes, rock glaciers, ice-cored moraines, push moraines), the topographical context (e.g. exposure to wind and solar radiation, remobilization of snow by avalanches) and regional aspects (e.g. precipitation events, timing and duration of the insulating snow cover). GST anomalies, indices and derivatives are analyzed over a large data set (~15 field sites) provided by the PERMOS network and different institutions within the SNF Sinergia project «The Evolution of Mountain Permafrost in Switzerland» (TEMPS, 2011-2014). First results show that GST anomalies observed during the past 10 to 15 years show largest disparities for different types of landforms and topographical contexts (because of modified snow cover dynamics). Despite of the complex and highly variable pattern of precipitation in the Swiss Alps, regional differences in GST anomalies remain remarkable small. These findings implicate that future permafrost monitoring based on GST does not necessarily depend on a dense network with a high number of field sites, but should cover at least one suitable spot per region with a variety of different topographical contexts.

  4. Energy balance in rainfed herbaceous crops in a semiarid environment for a 15-year experiment. 1. Impact of farming systems

    NASA Astrophysics Data System (ADS)

    Moreno, M. M.; Moreno, C.; Lacasta, C.; Tarquis, A. M.; Meco, R.

    2012-04-01

    During the last years, agricultural practices have led to increase yields by means of the massive consumption on non-renewable fossil energy. However, the viability of a production system does not depend solely on crop yield, but also on its efficiency in the use of available resources. This work is part of a larger study assessing the effects of three farming systems (conventional, conservation with zero tillage, and organic) and four barley-based crop rotations (barley monoculture and in rotation with vetch, sunflower and fallow) on the energy balance of crop production under the semi-arid conditions over a 15 year period. However, the present work is focused on the farming system effect, so crop rotations and years are averaged. Experiments were conducted at "La Higueruela" Experimental Farm (4°26' W, 40°04' N, altitude 450 m) (Spanish National Research Council, Santa Olalla, Toledo, central Spain). The climate is semi-arid Mediterranean, with an average seasonal rainfall of 480 mm irregularly distributed and a 4-month summer drought period. Conventional farming included the use of moldboard plow for tillage, chemical fertilizers and herbicides. Conservation farming was developed with zero tillage, direct sowing and chemical fertilizers and herbicides. Organic farming included the use of cultivator and no chemical fertilizers or herbicides. The energy balance method used required the identification and quantification of all the inputs and outputs implied, and the conversion to energy values by corresponding coefficients. The parameters considered were (i) energy inputs (EI) (diesel, machines, fertilizers, herbicides, seeds) (ii) energy outputs (EO) (energy in the harvested biomass), (iii) net energy produced (NE) (EI - EO), (iv) the energy output/input ratio (O/I), and (v) energy productivity (EP) (Crop yield/EI). EI was 3.0 and 3.5 times higher in conservation (10.4 GJ ha-1 year-1) and conventional (11.7 GJ ha-1 year-1) than in organic farming (3.41 GJ ha-1

  5. Section at Frame 195, Section at Frame 154, Section at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Section at Frame 195, Section at Frame 154, Section at Midship, Section at Frame 45, Longitudinal Section at Reinforced Bow Structure - US Coast Guard Icebreaker Glacier, Suisun Bay Reserve Fleet, Benicia, Solano County, CA

  6. Celestial Reference Frames

    NASA Astrophysics Data System (ADS)

    Jacobs, Christopher S.

    2013-03-01

    Concepts and Background: This paper gives an overview of modern celestial reference frames as realized at radio frequencies using the Very Long baseline Interferometry (VLBI) technique. We discuss basic celestial reference frame concepts, desired properties, and uses. We review the networks of antennas used for this work. We briefly discuss the history of the science of astrometry touching upon the discovery of precession, proper motion, nutation, and parallax, and the field of radio astronomy. Building Celestial Frames: Next, we discuss the multi-step process of building a celestial frame: First candidate sources are identified based on point-like properties from single dish radio telescopes surveys. Second, positions are refined using connected element interferometers such as the Very Large Array, and the ATCA. Third, positions of approximately milli-arcsecond (mas) accuracy are determined using intercontinental VLBI surveys. Fourth, sub-mas positions are determined by multiyear programs using intercontinental VLBI. These sub-mas sets of positions are then verified by multiple teams in preparation for release to non-specialists in the form of an official IAU International Celestial Reference Frame (ICRF). The process described above has until recently been largely restricted to work at S/X-band (2.3/8.4 GHz). However, in the last decade sub-mas work has expanded to include celestial frames at K-band (24 GHz), Ka-band (32 GHz), and Q-band (43 GHz). While these frames currently have the disadvantage of far smaller data sets, the astrophysical quality of the sources themselves improves at these higher frequencies and thus make these frequencies attractive for realizations of celestial reference frames. Accordingly, we review progress at these higher frequency bands. Path to the Future: We discuss prospects for celestial reference frames over the next decade. We present an example of an error budget for astrometric VLBI and discuss the budget's use as a tool for

  7. Celestial Reference Frame

    NASA Astrophysics Data System (ADS)

    Jacobs, Christopher S.

    2013-09-01

    Concepts and Background: This paper gives an overview of modern celestial reference frames as realized at radio frequencies using the Very Long baseline Interferometry (VLBI) technique. We discuss basic celestial reference frame concepts, desired properties, and uses. We review the networks of antennas used for this work. We briefly discuss the history of the science of astrometry touching upon the discovery of precession, proper motion, nutation, and parallax, and the field of radio astronomy. Building Celestial Frames: Next, we discuss the multi-step process of building a celestial frame: First candidate sources are identified based on point-like properties from single dish radio telescopes surveys. Second, positions are refined using connected element interferometers such as the Very Large Array, and the ATCA. Third, positions of approximately milli-arcsecond (mas) accuracy are determined using intercontinental VLBI surveys. Fourth, sub-mas positions are determined by multiyear programs using intercontinental VLBI. These sub-mas sets of positions are then verified by multiple teams in preparation for release to non-specialists in the form of an official IAU International Celestial Reference Frame (ICRF). The process described above has until recently been largely restricted to work at S/X-band (2.3/8.4 GHz). However, in the last decade sub-mas work has expanded to include celestial frames at K-band (24 GHz), Ka-band (32 GHz), and Q-band (43 GHz). While these frames currently have the disadvantage of far smaller data sets, the astrophysical quality of the sources themselves improves at these higher frequencies and thus make these frequencies attractive for realizations of celestial reference frames. Accordingly, we review progress at these higher frequency bands. Path to the Future: We discuss prospects for celestial reference frames over the next decade. We present an example of an error budget for astrometric VLBI and discuss the budget's use as a tool for

  8. Prevalence and self perception of Dental Fluorosis among 15 year old school children in Prakasham district of south India

    PubMed Central

    Naidu, Guntipalli M; Rahamthullah, S A K Uroof; Kopuri, Raj Kumar Chowdary; Kumar, Y Anil; Suman, S V; Balaga, Ramesh Naidu

    2013-01-01

    Background: To assess the Prevalence and self perception of dental fluorosis among 15 - year old school children. Materials & Methods: A cross sectional study was conducted on 840, 15 - year old school children from 12 schools of Prakasam district. After taking informed consent from their parents or legal representatives, an interview was conducted using a pretested questionnaire to collect the data regarding self perception of dental fluorosis, dental behaviour, and source of water and diet and socio demographic characters. Oral examination was done under natural light to score Deans fluorosis index. Statistical test used was chisquare test. Results: Study revealed that 82.04% of the study population were having dental fluorosis. Out of which only 42.3% were aware of the existing situations. 47.90% of boys are aware of dental fluorosis where as 40.50% of girls are aware of dental fluorosis. Fluorosis score in relation to gender is not statistically significant (chisquare (8.796);p=0.117). Conclusion: Dental fluorosis is a public health problem in Kanigiri town. As there was no study conducted in Kanigiri town even though it is one of the severely affected area in our country. Active steps must be taken to De fluoridate the water before distribution to reduce the morbidity associated with dental fluorosis in this area. How to cite this article: Naidu GM, Rahamthullah SA, Kopuri RK, Kumar YA, Suman SV, Balaga RN. Prevalence and self perception of Dental Fluorosis among 15 year old school children in Prakasham district of south India. J Int Oral Health 2013; 5(6):67-71. PMID:24453447

  9. Brainstem cavernoma hemorrhage during pregnancy in a 15-year-old: description of a unique neurosurgical approach.

    PubMed

    Ranger, Adrianna M; Chaudhary, Navjot; Avery, Michael; Lownie, Stephen

    2013-10-01

    Cavernous haemangiomas, or cavernous malformations, have been reported during pregnancy, most of which have been either supratentorial or spinal lesions. We encountered a 15-year old pregnant patient with a rapidly progressive and haemorrhagic brainstem cavernous haemangioma. The case presented here describes the history and findings of this patient, as well as the less-commonly utilized technique we used to access the floor of the fourth ventricle via occipital craniotomy for complete macroscopic resection of this lesion, resulting in the gradual return of most of her neurological deficits. PMID:23001930

  10. Bilateral pulmonary emboli after bilateral mastectomy in a 15-year-old boy with hypogonadism: A case report

    PubMed Central

    Piggott, JR; Yazdani, Arjang

    2010-01-01

    Pulmonary emboli are rare, yet serious, complications of body contouring surgery. When they occur, they more often follow as complications of long, invasive procedures in adults. The present report details a case of bilateral pulmonary emboli in an obese 15-year-old boy with hypogonadism undergoing bilateral mastectomy for gynecomastia. The diagnosis of bilateral pulmonary emboli was made on the basis of clinical presentation and positive ventilation/perfusion scan. The patient responded well to heparin anticoagulation treatment. The relevance of pediatric obesity, pediatric body contouring surgery and the risk of thromboembolic events in pediatric patients are discussed. PMID:22131848

  11. Control measures to trace ≤ 15-year-old contacts of index cases of active pulmonary tuberculosis.

    PubMed

    Oliveira, Cláudia Di Lorenzo; Melo, Angelita Cristine de; Oliveira, Lílian Ruth Silva de; Froede, Emerson Lopes; Camargos, Paulo

    2015-01-01

    This was descriptive study carried out in a medium-sized Brazilian city. In ≤ 15-year-old contacts of index cases of active pulmonary tuberculosis, we assessed compliance with the Brazilian national guidelines for tuberculosis control. We interviewed 43 contacts and their legal guardians. Approximately 80% of the contacts were not assessed by the municipal public health care system, and only 21% underwent tuberculin skin testing. The results obtained with the Chi-square Automatic Interaction Detector method suggest that health care teams have a biased attitude toward assessing such contacts and underscore the need for training health professionals regarding tuberculosis control programs.

  12. Control measures to trace ≤ 15-year-old contacts of index cases of active pulmonary tuberculosis

    PubMed Central

    Oliveira, Cláudia Di Lorenzo; de Melo, Angelita Cristine; de Oliveira, Lílian Ruth Silva; Froede, Emerson Lopes; Camargos, Paulo

    2015-01-01

    This was descriptive study carried out in a medium-sized Brazilian city. In ≤ 15-year-old contacts of index cases of active pulmonary tuberculosis, we assessed compliance with the Brazilian national guidelines for tuberculosis control. We interviewed 43 contacts and their legal guardians. Approximately 80% of the contacts were not assessed by the municipal public health care system, and only 21% underwent tuberculin skin testing. The results obtained with the Chi-square Automatic Interaction Detector method suggest that health care teams have a biased attitude toward assessing such contacts and underscore the need for training health professionals regarding tuberculosis control programs. PMID:26578137

  13. A successful treatment of hypercalcemia with zoledronic acid in a 15-year-old boy with acute lymphoblastic leukemia

    PubMed Central

    Park, Hye-Jin; Choi, Eun-Jin

    2016-01-01

    Severe hypercalcemia in children is a rare medical emergency. We present a case of a 15-year-old boy with hypercalcemia (total calcium level, 14.2 mg/dL) with a normal complete blood count, no circulating blasts in the peripheral blood film, and no other signs of acute lymphoblastic leukemia (ALL), including no signs of lymphadenopathy or hepatosplenomegaly. The hypercalcemia was successfully treated with zoledronic acid. As hypercalcemia can be the only presenting symptom of ALL in children, the diagnosis is often delayed. In children presenting with hypercalcemia, malignancies must be considered in the differential diagnosis. PMID:27462588

  14. Ontogeny of two-point discrimination for fingers and toes in children (ages 7 through 15 years).

    PubMed

    Richards, P M; Persinger, M A; Michel, R N

    1998-06-01

    Accuracies of two-point discrimination (successive 2-min increments between 0 and 10 mm) for the middle fingers and the middle toes for 87 children from ages 7 through 15 years were measured to obtain normative data. The finer discriminative capacity for the fingers rather than the toes was evident. Whereas discriminative accuracy approached the asymptote with distances equal to or greater than 4 mm for the fingers, distances equal to or greater than 8 mm were required for the toes. For this ontogenetic range, the effects for toes vs fingers was much greater than the effect size for age.

  15. 15 Years of CIAO

    NASA Astrophysics Data System (ADS)

    McDowell, Jonathan

    2014-11-01

    The first release of the Chandra data analysis system CIAO in the summer of 1999 enabled initial Chandra guest observer science. We continue to extend and improve the CIAO package, supporting both advanced use by experienced X-ray astronomers and simple analysis by novice users. Ongoing recent usability improvements include high level scripts to automate common, repetitive tasks and simplify the data reduction process, and improved support for merging observations that have been split due to thermal constraints. We present these improvements, discuss new documentation threads and present statistics on CIAO downloads and helpdesk usage.

  16. Modelling Survival and Mortality Risk to 15 Years of Age for a National Cohort of Children with Serious Congenital Heart Defects Diagnosed in Infancy

    PubMed Central

    Knowles, Rachel L.; Bull, Catherine; Wren, Christopher; Wade, Angela; Goldstein, Harvey; Dezateux, Carol

    2014-01-01

    Background Congenital heart defects (CHDs) are a significant cause of death in infancy. Although contemporary management ensures that 80% of affected children reach adulthood, post-infant mortality and factors associated with death during childhood are not well-characterised. Using data from a UK-wide multicentre birth cohort of children with serious CHDs, we observed survival and investigated independent predictors of mortality up to age 15 years. Methods Data were extracted retrospectively from hospital records and death certificates of 3,897 children (57% boys) in a prospectively identified cohort, born 1992–1995 with CHDs requiring intervention or resulting in death before age one year. A discrete-time survival model accounted for time-varying predictors; hazards ratios were estimated for mortality. Incomplete data were addressed through multilevel multiple imputation. Findings By age 15 years, 932 children had died; 144 died without any procedure. Survival to one year was 79.8% (95% confidence intervals [CI] 78.5, 81.1%) and to 15 years was 71.7% (63.9, 73.4%), with variation by cardiac diagnosis. Importantly, 20% of cohort deaths occurred after age one year. Models using imputed data (including all children from birth) demonstrated higher mortality risk as independently associated with cardiac diagnosis, female sex, preterm birth, having additional cardiac defects or non-cardiac malformations. In models excluding children who had no procedure, additional predictors of higher mortality were younger age at first procedure, lower weight or height, longer cardiopulmonary bypass or circulatory arrest duration, and peri-procedural complications; non-cardiac malformations were no longer significant. Interpretation We confirm the high mortality risk associated with CHDs in the first year of life and demonstrate an important persisting risk of death throughout childhood. Late mortality may be underestimated by procedure-based audit focusing on shorter-term surgical

  17. Impacts of artificial reservoirs on floristic diversity and plant functional traits in dry forests after 15 years.

    PubMed

    Lopes, S F; Vale, V S; Prado Júnior, J A; Schiavini, I

    2015-08-01

    Dams are of paramount importance to a wide variety of human services and many of their environmental problems are known; however, there are few studies in the world addressing the impacts on the native vegetation previously distant from water bodies which became close to the lakeshore created by a dam. Thus, this paper aims to analyze the responses of a dry forest to a dam after 15 years. For this, 20 random samples of 40 trees were made, 10 close to the lakeshore and 10 distant from it, by applying the central square point method. Close to the dam, we found higher values regarding basal area, number of trees, number of evergreen trees, and zoochoric syndrome, but there were lower values of Shannon's diversity index. Therefore, the impacts of the dam after 15 years caused several changes to the tree community. The greater basal area close to the dam suggests that water deficit during the dry season was decreased and plants have thicker trunks. On the other hand, this sector had much more zoochoric syndrome and a larger number of evergreen trees than plots which are distant from water, suggesting changes with regard to the community's ecological functions. Furthermore, structural floristic data shows that the sector close to the dam is less similar to other deciduous forests within the same geographical region than the sector distant from water, thus providing evidence of the impacts of dams on the tree community.

  18. Duration of immunity following immunization with live measles vaccine: 15 years of observation in Zhejiang Province, China.

    PubMed Central

    Dai, B.; Chen, Z. H.; Liu, Q. C.; Wu, T.; Guo, C. Y.; Wang, X. Z.; Fang, H. H.; Xiang, Y. Z.

    1991-01-01

    The duration of immunity following measles vaccination of 2882 immunized children has been investigated in a closed region of China for 15 years. A total of 1002 of the children were treated as primary immunization subjects, and 1547 as reimmunization subjects. These two cohorts were not in contact with known wild measles virus over the whole observation period, and the results obtained probably reflected the antibody responses to measles vaccine alone. The remaining 333 vaccinees came into contact with wild measles virus, and this permitted evaluation of the protective effect of the measles vaccines tested: 4 children experienced very mild clinical measles, and 329 experienced subclinical infection, including 12 who had had undetectable haemagglutination-inhibition antibodies for 9-10 years. These results indicate that the immunity induced by successful primary immunization may persist for at least 15 years. Within this period, a second dose of vaccine only induces low antibody responses which decrease rapidly to their original levels. This provides strong evidence that the immunity produced by primary immunization is long-lasting. However, there were some indications that reimmunization might produce better effects if live attenuated measles virus were used with a longer interval between doses. PMID:1934235

  19. Comparison of breast, cow, and soy feedings in the prevention of onset of allergic disease: a 15-year prospective study.

    PubMed

    Gruskay, F L

    1982-08-01

    It has been reported that the feeding of cow's milk may enhance the development of atopy in predisposed infants. A prospective study following children from birth through 15 years of age in a private pediatric practice was designed to determine if the food ingested during the first months of life is related to the development of atopy in the offspring of allergic families. Each of 328 children with a positive family history of allergy was assigned to one of three groups according to the feeding preference of the parents: 48 were fed breast milk; 79 soy-based formula; and 201, cow's milk formula. All groups had egg, citrus, tomato, and wheat restrictions as well as inhalant allergen avoidance. These were compared to a control group of 580 children with no family history of allergy. Breast fed infants were found to have approximately one-half the incidence of atopy of cow's milk or soy formula fed infants from atopic families when followed for up to 15 years. Soy feeding produced no advantage over cow's milk in the prophylaxis of allergic disease. There was a three-fold increase in clinically apparent atopic disease in offspring of allergic families when compared to controls but only a two-fold increase if the infant was breast fed. These results support the hypothesis that breast feeding and delay of exposure to known allergens may reduce the frequency of clinical allergic disease in the offspring of allergic families.

  20. International Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress.

    PubMed

    Woodward, D F; Jones, R L; Narumiya, S

    2011-09-01

    It is now more than 15 years since the molecular structures of the major prostanoid receptors were elucidated. Since then, substantial progress has been achieved with respect to distribution and function, signal transduction mechanisms, and the design of agonists and antagonists (http://www.iuphar-db.org/DATABASE/FamilyIntroductionForward?familyId=58). This review systematically details these advances. More recent developments in prostanoid receptor research are included. The DP(2) receptor, also termed CRTH2, has little structural resemblance to DP(1) and other receptors described in the original prostanoid receptor classification. DP(2) receptors are more closely related to chemoattractant receptors. Prostanoid receptors have also been found to heterodimerize with other prostanoid receptor subtypes and nonprostanoids. This may extend signal transduction pathways and create new ligand recognition sites: prostacyclin/thromboxane A(2) heterodimeric receptors for 8-epi-prostaglandin E(2), wild-type/alternative (alt4) heterodimers for the prostaglandin FP receptor for bimatoprost and the prostamides. It is anticipated that the 15 years of research progress described herein will lead to novel therapeutic entities. PMID:21752876

  1. Pattern of malignancies in children <15 years of age reported in Hadhramout Cancer Registry, Yemen between 2002 and 2014

    PubMed Central

    Jawass, Mazin A.; Al-Ezzi, Jalil I.; Gouth, Hanan S. Bin; Bahwal, Saleh A.; Bamatraf, Fawzia F.; Ba’amer, Abubakir A.

    2016-01-01

    Objectives: To describe the patterns of childhood cancers in Hadhramout Sector, Yemen between January 2002 and December 2014. Methods: This descriptive retrospective study was based on secondary data from Hadhramout Cancer Registry, Hadhramout, Yemen. All Yemeni children under age of 15 years, who were diagnosed with cancer were included. The International Childhood Cancer Classification system was used to categorize cancer types. Results: A total of 406 childhood cancers of both gender <15 years of age were reported. These represented 8.5% of all cases registered. The mean age was 7.34 ± 4.18 years. There were 240 males (59.1%) and 166 females (40.9%) with a male to female ratio of 1.4:1. Calculated incidence of cancer in children in this population is 1.9 per 100,000. The predominant age group was 5-9 years (35%) followed by 10-14 years (33.7%), and 0-4 years group (31%). The most common group of malignancies were hematological malignancies accounting for 47% of cases, followed by nervous system malignancies (15%). The most frequently reported cancer types were lymphoma (24%), leukemia (23%), carcinoma (13.1%), and central nervous system (CNS) tumors (11.6%). Conclusions: There is a lower frequency of childhood cancer in Hadhramout Sector when compared with developed countries. The most common cancers among children were lymphoma, leukemia, carcinoma, and CNS tumors. PMID:27146613

  2. Efficient key frames selection for panorama generation from video

    NASA Astrophysics Data System (ADS)

    Fadaeieslam, Mohammad Javad; Soryani, Mohsen; Fathy, Mahmood

    2011-04-01

    A video sequence consists of several hundred frames, and as a result, creating a panoramic image from these frames is a very time-consuming process. Consecutive frames have large overlap areas that do not provide much information. Therefore, some key frames must be extracted for better performance. There are a number of methods for key-frame selection that match all frames in a video sequence. We present a novel and efficient method to select key frames from video for creating a large panoramic mosaic without matching all frames. Consecutive frames are transformed and projected onto the common mosaic surface and the position of each corner of the next frame is predicted with a distinct Kalman filter on this surface. The overlap area between each predicted frame and its previous key frame is used as the criterion to select the next key frame. This method uses video information to reduce features and align frames with repeated structures more accurately. We show that this approach is an efficient preprocessing step and substantially reduces the time required to construct panorama from a video sequence.

  3. Tuberculosis situation among tribal population of Car Nicobar, India, 15 years after intensive tuberculosis control project and implementation of a national tuberculosis programme.

    PubMed Central

    Murhekar, M. V.; Kolappan, C.; Gopi, P. G.; Chakraborty, A. K.; Sehgal, S. C.

    2004-01-01

    OBJECTIVE: To assess the tuberculosis (TB) situation in the tribal community of Car Nicobar island 15 years after the national TB programme was implemented in this area after an intensive phase of TB control in 1986. METHODS: The entire population of Car Nicobar was enumerated through a house-to-house survey. Children aged <14 years were tuberculin tested and read for reaction sizes. Individuals aged >15 years were asked about the presence of chest symptoms (cough, chest pain, and unexplained fever for two weeks or longer and haemoptysis), and sputum samples were collected from patients with chest symptoms. Sputum samples were examined for presence of acid-fast bacilli. FINDINGS: Among the 4,543 children enumerated, 4,351 (95.8%) were tuberculin tested and read. Of the 981 children without bacille Calmette-Guerin scars, 161 (16.4%) were infected with TB. A total of 77 cases who were smear-positive for TB were detected from among 10,570 people aged >15 years; the observed smear-positive case prevalence was 728.5 per 100,000. The standardized prevalence of TB infection, annual risk of TB infection, and prevalence of cases smear-positive for TB were 17.0%, 2.5%, and 735.3 per 100,000, respectively. CONCLUSION: The prevalence of TB infection and smear-positive cases of TB increased significantly between 1986 and 2002. Such escalation took place despite the implementation of the national TB programme on this island, which was preceded by a set of special anti-TB measures that resulted in sputum conversion in a substantially large proportion of the smear-positive cases prevalent in the community. The most likely reason for the increase seems to be the absence of a district TB programme with enough efficiency to sustain the gains made from the one-time initial phase of special anti-TB measures. High risk of transmission of TB infection currently observed on this island calls for a drastic and sustained improvement in TB control measures. PMID:15640919

  4. Effectiveness of Ministry of Internal Affairs Regulation Number 15 Year 2008 about Mainstreaming Gender on Basic Education Level in the East Java, Indonesia

    ERIC Educational Resources Information Center

    Handayani, Trisakti; Widodo, Wahyu

    2016-01-01

    General purpose of this research are: assessing the implementation of Permendagri no. 15 year 2008 about Gender Mainstreaming on Basic Education Levels in the East Java Province, analyze the problem of the implementation of Permendagri no. 15 year 2008 about Gender Mainstreaming on Basic Education Levels in the East Java Province and analyze the…

  5. Nutrients and light limit biomass growth of N2-fixing but not non-fixing trees in tropical forests after 15 years of fertilization

    NASA Astrophysics Data System (ADS)

    Trierweiler, Annette; Wright, Joseph; Winter, Klaus; Hedin, Lars

    2015-04-01

    Tropical forests contribute a major fraction to the land C sink but the role of soil nutrients in limiting tree biomass growth in response to rising atmospheric CO2 is poorly known. Recent findings suggest that, following disturbance, successionally young forests may be deficient in nitrogen (N) and/or phosphorus (P), however nutrient manipulations of mature forests have revealed surprisingly weak effects of nutrients on the stem growth of mature individual trees. It is unclear how such weak experimental nutrient effects are reconciled with the existence of broad geographical correlations between soil nutrients and forest biomass growth. While tree growth is a complex function of nutrients, light, and canopy status, it is plausible that responses differ across different plant functional types. Here we use data from the longest running tropical fertilization experiment to ask first whether different functional groups have different nutrient needs, second, whether a differential nutrient limitation response will affect biomass accretion, and third, whether there is an interactive light-nutrient effect. Finally we examined how nutrient responses changed over time. We show that, in an intact and biodiverse mature tropical forest in Panama, N2-fixing trees more than double their basal area growth rate when exposed to increased soil P and N in the first 11 years of fertilization, for an overall 60% increase over 15 years. In contrast, there was no effect of nutrient treatment on the growth of non-fixing trees. We found a strong interactive effect of soil nutrients and light on fixer tree growth as the greatest growth response was in mature canopy-level trees with full access to light and potentially new nitrogen through fixation. In addition, the positive nutrient effect declined over the 15 years, rather than the expected increase. Our findings suggest that N2-fixing tree species may play a disproportionately important role in governing tropical forest response to

  6. Lifestyle counseling for type 2 diabetes risk reduction in Dutch primary care: results of the APHRODITE study after 0.5 and 1.5 years.

    PubMed

    Vermunt, Paulina W A; Milder, Ivon E J; Wielaard, Frits; de Vries, Jeanne H M; van Oers, Hans A M; Westert, Gert P

    2011-09-01

    OBJECTIVE To study the overall effect of the Active Prevention in High-Risk Individuals of Diabetes Type 2 in and Around Eindhoven (APHRODITE) lifestyle intervention on type 2 diabetes risk reduction in Dutch primary care after 0.5 and 1.5 years and to evaluate the variability between general practices. RESEARCH DESIGN AND METHODS Individuals at high risk for type 2 diabetes (Finnish Diabetes Risk Score ≥13) were randomly assigned into an intervention group (n = 479) or a usual-care group (n = 446). Comparisons were made between study groups and between general practices regarding changes in clinical and lifestyle measures over 1.5 years. Participant, general practitioner, and nurse practitioner characteristics were compared between individuals who lost weight or maintained a stable weight and individuals who gained weight. RESULTS Both groups showed modest changes in glucose values, weight measures, physical activity, energy intake, and fiber intake. Differences between groups were significant only for total physical activity, saturated fat intake, and fiber intake. Differences between general practices were significant for BMI and 2-h glucose but not for energy intake and physical activity. In the intervention group, the nurse practitioners' mean years of work experience was significantly longer in individuals who were successful at losing weight or maintaining a stable weight compared with unsuccessful individuals. Furthermore, successful individuals more often had a partner. CONCLUSIONS Risk factors for type 2 diabetes could be significantly reduced by lifestyle counseling in Dutch primary care. The small differences in changes over time between the two study groups suggest that additional intervention effects are modest. In particular, the level of experience of the nurse practitioner and the availability of partner support seem to facilitate intervention success. PMID:21775759

  7. Antibody persistence and immune memory in adults, 15 years after a three-dose schedule of a combined hepatitis A and B vaccine.

    PubMed

    Van Damme, P; Leroux-Roels, G; Crasta, P; Messier, M; Jacquet, J-M; Van Herck, K

    2012-01-01

    A combined hepatitis A and B vaccine is available since 1996. Two separate open-label primary studies evaluated the immunogenicity and safety of this hepatitis A and B vaccine (720 EI.U of HAV and 20 µg of HBsAg) in 306 healthy subjects aged 17-43 years who received three doses of the vaccine following a 0, 1, and 6 months schedule. These subjects were followed up annually for the next 15 years to evaluate long-term persistence of anti-HAV and anti-HBs antibodies. The subjects whose antibody concentrations fell below the cut-offs between Year 11 and Year 15 (anti-HAV: <15 mIU/ml; anti-HBs: <10 mIU/ml) were offered an additional dose of the appropriate monovalent hepatitis A and/or B vaccine. In subjects who received the additional vaccine dose, a blood sample was collected 1 month after vaccination. At the Year 15 time point, all subjects in Study A and Study B were seropositive for anti-HAV antibodies and 89.3% and 92.9% of subjects in the respective studies had anti-HBs antibody concentrations ≥10 mIU/ml. Four subjects (two in each study) received an additional dose of monovalent hepatitis B vaccine and mounted anamnestic responses to vaccination. No vaccine-related serious adverse events were reported. This study confirms the long-term immunogenicity of the three-dose regimen of the combined hepatitis A and B vaccine, as eliciting long-term persistence of antibodies and immune memory against hepatitis A and B for up to at least 15 years after a primary vaccination.

  8. Parenting Stress and Child Behavior Problems within Families of Children with Developmental Disabilities: Transactional Relations across 15 Years

    PubMed Central

    Woodman, Ashley C.; Mawdsley, Helena P.; Hauser-Cram, Penny

    2014-01-01

    Parents of children with developmental disabilities (DD) are at increased risk of experiencing psychological stress compared to other parents. Children’s high levels of internalizing and externalizing problems have been found to contribute to this elevated level of stress. Few studies have considered the reverse direction of effects, however, in families where a child has a DD. The present study investigated transactional relations between child behavior problems and maternal stress within 176 families raising a child with early diagnosed DD. There was evidence of both child-driven and parent-driven effects over the 15-year study period, spanning from early childhood (age 3) to adolescence (age 18), consistent with transactional models of development. Parent-child transactions were found to vary across different life phases and with different domains of behavior problems. PMID:25462487

  9. Jaw and tooth abnormalities detected on panoramic radiographs in New Zealand children aged 10-15 years.

    PubMed

    Cholitgul, W; Drummond, B K

    2000-03-01

    Panoramic radiographs of 1,608 children and adolescents aged 10 to 15 years (797 males and 811 females) were reviewed to determine the prevalence of tooth and jaw abnormalities. Abnormalities were detected on 21 percent of the radiographs (23 percent females and 17.3 percent males); 879 teeth were diagnosed with abnormalities on 331 radiographs. The more common abnormalities were malpositioned teeth, missing teeth, misshaped teeth, and teeth with hypoplastic appearance. Bony abnormalities and growth problems were detected in a few radiographs. This study demonstrates the value of panoramic radiography in detecting or confirming dental abnormalities, and supports recommendations on the use of panoramic radiography to aid in the assessment of dental development. PMID:10860374

  10. Diagnosis and management of sports-related concussion: a 15-year-old athlete with a concussion.

    PubMed

    Zafonte, Ross

    2011-07-01

    Concussion in youth athletes is a growing problem worldwide. During the past decade, significant progress has been made in standardization of the assessment of young athletes, and a growing appreciation of metabolic vulnerability, activity, and cognitive challenges has led to guidelines and suggestions for rest from the field as well as cognitive rest from school. Outcome data have begun to establish groups linked to symptom class, genetics, and sex who are at risk of worse outcomes from concussions. Decisions regarding return to activity are now based on at-rest symptoms, graded increases in activity, and neuropsychological testing. Using the case of Ms X, a 15-year-old otherwise healthy high school student who fell while skiing, evaluation, prognosis, and management of concussion are discussed.

  11. Direct adhesive pin-retained restorations for severely worn dentition treatment: a 1.5-year follow-up report.

    PubMed

    de Andrade, Camila Lima; Gonçalves, Thais Marques Simek Vega; Santos, Ícaro Leite dos; Barros, Michel Silva; Araújo, Nubia Rafaela Ribeiro; Cury, Altair Antoninha Del Bel

    2014-01-01

    Excessive occlusal surface wear can result in occlusal disharmony, functional and esthetic impairment. As a therapeutic approach, conventional single crowns have been proposed, but this kind of treatment is complex, highly invasive and expensive. This case report describes the clinical outcomes of an alternative minimally invasive treatment based on direct adhesive-pin retained restorations. A 64-year-old woman with severely worn dentition, eating problems related to missing teeth and generalized tooth hypersensitivity was referred for treatment. Proper treatment planning based on the diagnostic wax-up simulation was used to guide the reconstruction of maxillary anterior teeth with direct composite resin over self-threading dentin pins. As the mandibular remaining teeth were extremely worn, a tooth-supported overdenture was installed. A stabilization splint was also used to protect the restorations. This treatment was a less expensive alternative to full-mouth rehabilitation with positive esthetic and functional outcomes after 1.5 years of follow-up.

  12. Stable isotope analysis of a newly established macrofaunal food web 1.5 years after the Hebei Spirit oil spill.

    PubMed

    Han, Eunah; Park, Hyun Je; Bergamino, Leandro; Choi, Kwang-Sik; Choy, Eun Jung; Yu, Ok Hwan; Lee, Tae Won; Park, Heung-Sik; Shim, Won Joon; Kang, Chang-Keun

    2015-01-15

    We examined trophic relationships in a newly established community 1.5 years after the Hebei Spirit oil spill on the west coast of Korea. Carbon and nitrogen stable isotope ratios in consumers and their potential food sources were compared between the oil-spill site and reference site, located 13.5 km from the oil-spill spot. The isotopic mixing model and a novel circular statistics rejected the influx of petrogenic carbon into the community and identified spatial consistencies such as the high contributions of microphytobenthos, food-chain length, and the isotopic niche of each feeding guild between sites. We suggested that high level of trophic plasticity and the prevalence of omnivory of consumers may promote the robustness of food web against the oil contamination. Furthermore, we highlighted the need of holistic approaches including different functional groups to quantify changes in the food web structure and assess the influence of different perturbations including oil spill.

  13. The Adventitia Resection in Treatment of Liver Hydatid Cyst: A Case Report of a 15-Year-Old Boy

    PubMed Central

    Ma, Zhenhua; Yang, Wei; Yao, Yingmin; Liu, Qingguang

    2014-01-01

    Human hydatid disease is a significant health problem in endemic regions caused by the larval form of Echinococcus granulosus. In this paper, we report a case of liver hydatid cyst. The patient, a 15-year-old boy, presented with a history of intermittent upper abdominal pain of a few-month duration was referred to our hospital for investigation. Computed tomographic scan and laboratory test suggested a hydatid cyst in the right lobe of liver. The adventitia resection of hydatid cyst was smoothly performed as there was a less bloody virtual space between adventitia and outer membrane. Our diagnosis was made using an imaging approach and was confirmed during surgery. We proposed the adventitia resection of hydatid cyst could be safe and easy to perform with low risk of bleeding and bile leakage. PMID:24782939

  14. Late outcome of very severe blunt head trauma: a 10-15 year second follow-up.

    PubMed Central

    Thomsen, I V

    1984-01-01

    Forty patients with very severe blunt head trauma (post-traumatic amnesia greater than or equal to 1 month) were initially examined at an average of 4.5 months after the injury. The patients were visited in their homes 2.5 years and 10-15 years after the accident and questionnaires were presented to patients, relatives and/or staff. Though physical impairment, dysarthria and defects of memory remained severe in many cases, the psychosocial sequelae presented the most serious problems. Permanent changes in personality and emotion were reported in two thirds and were especially frequent among the youngest patients. The worse overall outcome was seen in cases with severe brainstem involvement or anterior lesions or both. In spite of the great frequency of deficits long-term improvement of functional state was common and several regained at least some work capacity. PMID:6707671

  15. Individuality and contextual influences on drug dependence: a 15-year Prospective longitudinal study of adolescents from Harlem.

    PubMed

    Brook, Judith S; Lee, Jung Yeon; Brown, Elaine N; Finch, Stephen J; Brook, David W

    2012-01-01

    In this 15-year longitudinal study the authors investigated individual and contextual factors that predispose adolescents from a disadvantaged urban area to drug dependence in adulthood. Adolescents were recruited from schools serving East Harlem in New York City. Of the 838 participants followed to adulthood, 59% were women, 55% were African American, and 45% were Puerto Rican. Self-report data were obtained on externalizing and internalizing problems, substance use, and contextual influences across adolescence and young adulthood. Drug dependence was assessed in adulthood. Multivariate logistic regressions of drug dependence were performed on the whole sample and separately by gender. Each of the domains was associated with adult drug dependence. Although mean gender differences were found, most associations of risk factors with drug dependence did not vary significantly by gender. Treating externalizing and internalizing problems, reducing substance use, and providing coping skills for adverse contextual influences in adolescence and young adulthood may reduce the likelihood of becoming drug dependent in adulthood.

  16. Retrospective review of the case of cutaneous anthrax-malignant pustule from 1995 in 15-year old girl.

    PubMed

    Kajfasz, Piotr; Bartoszcze, Michał; Borkowski, Piotr Karol; Basiak, Wojciech

    2014-01-01

    A 15-year-old girl was admitted to our Department with cutaneous lesion resembling black eschar. Anamnesis revealed that before getting ill she was wearing pullover made of rough sheep's wool and ornaments made of leather like straps. Cutaneous anthrax was confirmed by identification of B. anthracis in specimens from weeping ulceration, culture from black eschar, thermoprecipitation test, and bioassay on guinea pig. The girl was treated with crystalline Penicillin. She responded well to the therapy and recovered after 28 days. What attracts attention in presented case is the fact that the girl didn't belong to high risk group of human anthrax, which might lead to misdiagnosis. In 1990-1999, Poland there were reported 22 cases of anthrax - it was almost exclusively cutaneous form. In the years following 1999 antrax was reported even less often - in the period 1991-2013 it was recorded a total of 26 cutaneous anthrax cases.

  17. Discriminatory power of game-related statistics in 14-15 year age group male volleyball, according to set.

    PubMed

    García-Hermoso, Antonio; Dávila-Romero, Carlos; Saavedra, Jose M

    2013-02-01

    This study compared volleyball game-related statistics by outcome (winners and losers of sets) and set number (total, initial, and last) to identify characteristics that discriminated game performance. Game-related statistics from 314 sets (44 matches) played by teams of male 14- to 15-year-olds in a regional volleyball championship were analysed (2011). Differences between contexts (winning or losing teams) and "set number" (total, initial, and last) were assessed. A discriminant analysis was then performed according to outcome (winners and losers of sets) and "set number" (total, initial, and last). The results showed differences (winning or losing sets) in several variables of Complexes I (attack point and error reception) and II (serve and aces). Game-related statistics which discriminate performance in the sets index the serve, positive reception, and attack point. The predictors of performance at these ages when players are still learning could help coaches plan their training. PMID:23829141

  18. Variability in lateralised blood flow response to language is associated with language development in children aged 1-5 years.

    PubMed

    Kohler, M; Keage, H A D; Spooner, R; Flitton, A; Hofmann, J; Churches, O F; Elliott, S; Badcock, N A

    2015-01-01

    The developmental trajectory of language lateralisation over the preschool years is unclear. We explored the relationship between lateralisation of cerebral blood flow velocity response to object naming and cognitive performance in children aged 1-5 years. Functional transcranial Doppler ultrasound was used to record blood flow velocity bilaterally from middle cerebral arteries during a naming task in 58 children (59% male). At group level, the Lateralisation Index (LI) revealed a greater relative increase in cerebral blood flow velocity within the left as compared to right middle cerebral artery. After controlling for maternal IQ, left-lateralised children displayed lower expressive language scores compared to right- and bi-lateralised children, and reduced variability in LI. Supporting this, greater variability in lateralised response, rather than mean response, was indicative of greater expressive language ability. Findings suggest that a delayed establishment of language specialisation is associated with better language ability in the preschool years.

  19. Antibiotic prescribing of village doctors for children under 15 years with upper respiratory tract infections in rural China

    PubMed Central

    Zhang, Zhixia; Zhan, Xingxin; Zhou, Hongjun; Sun, Fang; Zhang, Heng; Zwarenstein, Merrick; Liu, Qian; Li, Yingxue; Yan, Weirong

    2016-01-01

    Abstract The aim of this study was to explore the knowledge, attitudes, and practices of village doctors regarding the prescribing of antibiotics for children under 15 years with upper respiratory tract infections (URTIs) in rural China. Twelve focus group discussions (FGDs) were conducted in Xianning, a prefecture-level city in rural China, during December 2014. We conducted 6 FGDs with 35 village doctors, 3 with 13 primary caregivers (11 parents), and 3 with 17 directors of township hospitals, county-level health bureaus, county-level Centers for Disease Control and Prevention, or county-level Chinese Food and Drug Administration offices. Audio records of the interviews were transcribed verbatim and analyzed using the thematic analysis approach. Participants believed that unnecessary antibiotic prescribing for children under 15 years with The occurrence of URTIs was a problem in village clinics in rural China. The discussions revealed that most of the village doctors had inadequate knowledge and misconceptions about antibiotic use, which was an important factor in the unnecessary prescribing. Village doctors and directors reported that the doctors’ fear of complications, the primary caregivers’ pressure for antibiotic treatment, and the financial considerations of patient retention were the main factors influencing the decision to prescribe antibiotics. Most of the primary caregivers insisted on antibiotics, even when the village doctors were reluctant to prescribe them, and they preferred to go to see those village doctors who prescribed antibiotics. The interviewees also gave their opinions on what would be the most effective measures for optimizing antibiotic prescriptions; these included educational/training campaigns, strict regulations on antibiotic prescription, and improved supervision. Findings emphasized the need to improve the dissemination of information and training/education, and implement legislation on the rational use of antibiotics. And it

  20. Informative-frame filtering in endoscopy videos

    NASA Astrophysics Data System (ADS)

    An, Yong Hwan; Hwang, Sae; Oh, JungHwan; Lee, JeongKyu; Tavanapong, Wallapak; de Groen, Piet C.; Wong, Johnny

    2005-04-01

    Advances in video technology are being incorporated into today"s healthcare practice. For example, colonoscopy is an important screening tool for colorectal cancer. Colonoscopy allows for the inspection of the entire colon and provides the ability to perform a number of therapeutic operations during a single procedure. During a colonoscopic procedure, a tiny video camera at the tip of the endoscope generates a video signal of the internal mucosa of the colon. The video data are displayed on a monitor for real-time analysis by the endoscopist. Other endoscopic procedures include upper gastrointestinal endoscopy, enteroscopy, bronchoscopy, cystoscopy, and laparoscopy. However, a significant number of out-of-focus frames are included in this type of videos since current endoscopes are equipped with a single, wide-angle lens that cannot be focused. The out-of-focus frames do not hold any useful information. To reduce the burdens of the further processes such as computer-aided image processing or human expert"s examinations, these frames need to be removed. We call an out-of-focus frame as non-informative frame and an in-focus frame as informative frame. We propose a new technique to classify the video frames into two classes, informative and non-informative frames using a combination of Discrete Fourier Transform (DFT), Texture Analysis, and K-Means Clustering. The proposed technique can evaluate the frames without any reference image, and does not need any predefined threshold value. Our experimental studies indicate that it achieves over 96% of four different performance metrics (i.e. precision, sensitivity, specificity, and accuracy).

  1. Aluminum space frame technology

    SciTech Connect

    Birch, S.

    1994-01-01

    This article examines the increased application of aluminum to the construction of automobile frames. The topics of the article include a joint venture between Audi and Alcoa, forms in which aluminum is used, new alloys and construction methods, meeting rigidity and safety levels, manufacturing techniques, the use of extrusions, die casting, joining techniques, and pollution control during manufacturing.

  2. Framing Evolution Discussion Intellectually

    ERIC Educational Resources Information Center

    Oliveira, Alandeom W.; Cook, Kristin; Buck, Gayle A.

    2011-01-01

    This study examines how a first-year biology teacher facilitates a series of whole-class discussions about evolution during the implementation of a problem-based unit. A communicative theoretical perspective is adopted wherein evolution discussions are viewed as social events that the teacher can frame intellectually (i.e., present or organize as…

  3. Popcorn Story Frames.

    ERIC Educational Resources Information Center

    DiLella, Carol Ann

    This paper presents "popcorn story frames"--holistic outlines that facilitate comprehension when reading and writing stories, useful for outlining stories read and for creating outlines for original student stories--that are particularly useful for elementary and intermediate school students. "Popcorn" pops in a horizontal manner rather than in a…

  4. Frame dragging and superenergy

    SciTech Connect

    Herrera, L.; Di Prisco, A.; Carot, J.

    2007-08-15

    We show that the vorticity appearing in stationary vacuum spacetimes is always related to the existence of a flow of superenergy on the plane orthogonal to the vorticity vector. This result, together with the previously established link between vorticity and superenergy in radiative (Bondi-Sachs) spacetimes, strengthens further the case for this latter quantity as the cause of frame dragging.

  5. Disformal gravity theories: A Jordan frame analysis

    NASA Astrophysics Data System (ADS)

    Sakstein, Jeremy; Verner, Sarunas

    2015-12-01

    The Jordan frame action for general disformal theories is presented and studied for the first time, motivated by several unresolved mysteries that arise when working in the Einstein frame. We present the Friedmann equations and, specializing to exponential functions, study the late-time cosmology using both dynamical systems methods and by finding approximate solutions. Our analysis reveals that either the disformal effects are irrelevant or the Universe evolves towards a phantom phase where the equation of state of dark energy is -3 . There is a marginal case where the asymptotic state of the Universe depends on the model parameters and de Sitter solutions can be obtained. Our findings indicate that the metric singularity found using the Einstein frame construction corresponds to phantom behavior in the Jordan frame and we argue that this is the case for general disformal theories.

  6. Quantitative rotating frame relaxometry methods in MRI.

    PubMed

    Gilani, Irtiza Ali; Sepponen, Raimo

    2016-06-01

    Macromolecular degeneration and biochemical changes in tissue can be quantified using rotating frame relaxometry in MRI. It has been shown in several studies that the rotating frame longitudinal relaxation rate constant (R1ρ ) and the rotating frame transverse relaxation rate constant (R2ρ ) are sensitive biomarkers of phenomena at the cellular level. In this comprehensive review, existing MRI methods for probing the biophysical mechanisms that affect the rotating frame relaxation rates of the tissue (i.e. R1ρ and R2ρ ) are presented. Long acquisition times and high radiofrequency (RF) energy deposition into tissue during the process of spin-locking in rotating frame relaxometry are the major barriers to the establishment of these relaxation contrasts at high magnetic fields. Therefore, clinical applications of R1ρ and R2ρ MRI using on- or off-resonance RF excitation methods remain challenging. Accordingly, this review describes the theoretical and experimental approaches to the design of hard RF pulse cluster- and adiabatic RF pulse-based excitation schemes for accurate and precise measurements of R1ρ and R2ρ . The merits and drawbacks of different MRI acquisition strategies for quantitative relaxation rate measurement in the rotating frame regime are reviewed. In addition, this review summarizes current clinical applications of rotating frame MRI sequences. Copyright © 2016 John Wiley & Sons, Ltd.

  7. One-Shot Measurement of Spin-Lattice Relaxation Times in the Off-Resonance Rotating Frame of Reference with Applications to Breast

    NASA Astrophysics Data System (ADS)

    Fairbanks, Ethan Jefferson

    1994-01-01

    Off-resonance spin locking makes use of the novel relaxation time T_{1rho} ^{rm off}, which may be useful in characterizing breast disease. Knowledge of T _{rm 1rho}^{rm off} is essential for optimization of spin -locking imaging methods. The purpose of this work was to develop an optimal imaging technique for in vivo measurement of T_{rm 1rho}^ {rm off}. Measurement of T _{1rho}^{rm off } using conventional methods requires long exam times which are not suitable for patients. Exam time may be shortened by utilizing a one-shot method developed by Look and Locker, making in vivo measurements possible. The imaging method consisted of a 180^circ inversion pulse followed by a series of small-angle alpha pulses to tip a portion of the longitudinal magnetization into the transverse plane for readout. During each relaxation interval (between alpha pulses), a spin-locking pulse was applied off-resonance to achieve T_ {1rho}^{rm off} relaxation. The value of T_{rm 1rho}^{rm off} was then determined using a three-parameter non-linear least-squares fitting procedure. Values of T_ {1rho}^{rm off} were measured for normal and pathologic breast tissues at several resonant offsets. These measurements revealed that image contrast can be manipulated by altering the resonant offset of the spin-locking pulse. Whereas T _1 relaxation times were nearly identical for normal and cancerous tissues, T_{1 rho}^{rm off} relaxation times differed significantly. These results may be useful in improving image contrast in magnetic resonance imaging.

  8. A 15-year warranty period for asymptomatic individuals without coronary artery calcium: a prospective follow-up of 9715 individuals

    PubMed Central

    Valenti, Valentina; Hartaigh, Bríain ó; Heo, Ran; Cho, Iksung; Schulman-Marcus, Joshua; Gransar, Heidi; Truong, Quynh A.; Shaw, Leslee J.; Knapper, Joseph; Kelkar, Anita A.; Sandesara, Pratik; Lin, Fay Y.; Sciarretta, Sebastiano; Chang, Hyuk-Jae; Callister, Tracy Q.; Min, James K

    2015-01-01

    Objective To examine long-term prognosis of a zero coronary artery calcium (CAC) score among asymptomatic individuals and its associated warranty period. Background Emerging evidence supports CAC=0 as a favorable cardiovascular short-to-intermediate term prognostic factor. Methods 9715 individuals undergoing CAC imaging were stratified by age, Framingham risk score (FRS) and Adult Treatment Panel III (NCEP ATP III) categories and followed for a mean of 14.6 (12.9–16.8) years. Cox regression, area under the receiver operating characteristic curve (AUC) and net reclassification information (NRI) were used to assess all-cause mortality, discrimination and reclassification of CAC=0 compared with FRS and NCEP ATP III, respectively. A warranty period was pre-defined as <1% annual mortality rate. Vascular age was estimated by linear regression. Results Among 4864 individuals with baseline CAC=0 (mean age 52.1±10.8 years; 57.9% male), 229 deaths occurred. The warranty period of CAC=0 was almost 15 years for individuals at low and intermediate risk with no significant differences regarding age and gender. CAC=0 was associated with a vascular age of 1, 10, 20, and 30 years below chronologic age for individuals between 50–59, 60–69, 70–79, and ≥80 years, respectively. CAC score was the strongest predictor of death (HR 2.67, 95% CI 2.29–3.11) that enabled discrimination and consistent reclassification beyond FRS (AUC 0.71 vs. 0.64, p<0.001) and NCEP ATP III (AUC 0.72 vs. 0.64, p<0.001). Conclusions CAC=0 confers a 15-year warranty period against mortality among individuals at low-to-intermediate risk, which is unaffected by age or gender. Furthermore, in individuals considered at high-risk by clinical risk scores the presence of CAC=0 confers better survival than in individuals at low-to-intermediate risk but with any CAC. PMID:26189116

  9. Evaluation Efficacy of Ferrous Sulfate Therapy on Headaches of 5-15 Years Old Iron Deficient Children with Migraine

    PubMed Central

    Fallah, R; Zare Bidoki, S; Ordooei, M

    2016-01-01

    Background Some researches have shown the association between iron deficiency and migraine headache in adults. The aim of present study was to evaluate efficacy of ferrous sulfate treatment on migraine headaches of 5-15 years old migraineur children with iron deficiency. Materials and Methods In a quasi- experimental study, monthly frequency, severity, duration and disability of headaches of 5-15 years old migraineur children that prophylactic therapy was indicated in them and had iron deficiency who were referred to Pediatric Neurology Clinic of Shahid Sadoughi University of Medical Sciences, Yazd, Iran between 2013 and 2015 and were treated with 2mg/kg/day topiramate plus 4mg/kg/day of ferrous sulfate for three consecutive months, were evaluated and headache characteristics before and after treatment were compared. Results In this study, 98 children with mean age of 9.72±3.19 were evaluated that 31children (31.6%) had iron deficiency. Monthly frequency (22.89±7.18 vs.14.5±4.56, P= 0.02), severity score (8.12± 1.76 vs. 5.03±1.15, P= 0.02) and disability score of headache (38.23±10.7vs. 30.12±7.46, P= 0.03) were more in children with iron deficiency. Iron therapy was effective in decreasing of monthlyfrequency 22.89± 7.18 vs. 10.13±4.51, P = 0.001), severity score (8.12±1.76 vs. 5.11±1.62, P =0.001), duration (2.14±1.23 vs.1.14±1.01, P= 0.001) and disability score of headache (38.23±10.7 vs. 22.87±8.65, P= 0.01). Conclusion In children, iron deficiency increased monthly frequency, severity and disability of migraine headache and ferrous sulfate can be used as a safe and effective drug in migraine prophylaxis. PMID:27222700

  10. A two-dose schedule for combined hepatitis A and B vaccination in children aged 6-15 years.

    PubMed

    Kurugöl, Zafer; Mutlubaş, Fatma; Ozacar, Tijen

    2005-04-22

    A combined hepatitis A and B vaccine, Twinrix, in a paediatric formulation for ages 1-15 years and in an adult formulation for those ages 16 years and older, became commercially available in Turkey as well as in many countries. It is administered according to a three-dose schedule (0, 1 and 6 months). A reduction in the number of doses would improve the compliance rate and reduce administration costs. Therefore, we planned a trial evaluation of the immunogenicity, safety and reactogenicity profile of a high-dose combined hepatitis A and B vaccine, administered in two doses, compared with the profile of a paediatric-dose combined vaccine, administered in three doses, in healthy children aged 6-15 years. One hundred children were randomly attributed to the two study groups. The first group (paediatric-dose vaccine group) received the licensed Twinrix Paediatric, at months 0, 1 and 6; the second group (high-dose vaccine group) received the high-dose vaccine, following a 0, 6 months schedule. The reactogenicity was assessed after each vaccine dose. The immunogenicity was evaluated by testing for anti-HBs and anti-HAV antibodies. Seroconversion rates and geometric mean titres (GMTs) were compared. Both formulations of the combined vaccine were well tolerated. The high-dose combined vaccine administered in two doses, elicits satisfactory immunogenicity profiles, similar to those elicited by the paediatric vaccine administered in three doses. On completion of the vaccination schedule in the two groups all children were protected against hepatitis B and immune for hepatitis A. Anti-HAV GMTs after completion of the vaccination schedule were 7163 mlU/ml in the paediatric-dose group, 8241 mlU/ml in the high-dose group; anti-HBs GMTs were 8679 and 4583 mlU/ml, respectively. These results indicate that a two-dose schedule, compared with the standard three-dose schedule, offers fewer injections for satisfactory protection against the two infections. This means fewer clinic

  11. Nanosecond frame cameras

    SciTech Connect

    Frank, A M; Wilkins, P R

    2001-01-05

    The advent of CCD cameras and computerized data recording has spurred the development of several new cameras and techniques for recording nanosecond images. We have made a side by side comparison of three nanosecond frame cameras, examining them for both performance and operational characteristics. The cameras include; Micro-Channel Plate/CCD, Image Diode/CCD and Image Diode/Film; combinations of gating/data recording. The advantages and disadvantages of each device will be discussed.

  12. Frame for a firearm

    DOEpatents

    Crandall, David L.; Watson, Richard W.

    2008-03-04

    A firearm frame which is adapted to be disposed in operative relationship as a component part of a firearm, the firearm having disposed in operative relationships each with one or more of the others, a barrel, a receiver, and at least one firing mechanism; wherein the barrel and receiver form operative parts of a movable assembly and the at least one firing mechanism is disposed in a substantially stationary operative relationship therewith; the firearm frame including at least one elongated support structure discrete from the barrel and receiver, the elongated support structure being adapted to directly support the movable assembly in an operative movable relationship therewith; whereby at least one of the barrel and receiver is in direct contact with and movable on the elongated support structure; and, a firing mechanism support structure connected to the at least one elongated support structure, the firing mechanism support structure being adapted to have the firing mechanism connected thereto; the firearm frame also directly supporting the movable assembly and the firing mechanism in corresponding movable and stationary operative relationships each with the other.

  13. Prevalence of Tuberculosis among Veterans, Military Personnel and their Families in East Azerbaijan Province Violators of the last 15 Years.

    PubMed

    Azad Aminjan, Maboud; Moaddab, Seyyed Reza; Hosseini Ravandi, Mohammad; Kazemi Haki, Behzad

    2015-10-01

    Nowadays in the world, tuberculosis is the second largest killer of adults after HIV. Due to the location of presidios that is mostly located in hazardous zones soldiers and army personnel are considered high risk, therefore we decided to determine the prevalence of tuberculosis status in this group of people. This was a cross-sectional descriptive research that studied the prevalence of pulmonary tuberculosis in soldiers and military personnel in the last 15 years in tuberculosis and lung disease research center at Tabriz University of Medical Sciences. The statistical population consisted of all the soldiers and military personnel. The detection method in this study was based on microscopic examination following Ziehl-Neelsen Stain and in Leuven Stein Johnson culturing. Descriptive statistics was used for statistical analysis and statistical values less than 0.05 were considered significant. By review information in this center since the 1988-2013 with 72 military personnel suffering from tuberculosis, it was revealed that among them 30 women, 42 men, 14 soldiers, 29 family members, and 29 military personnel are pointed. A significant correlation was found between TB rates among military personnel and their families. Although in recent years, the national statistics indicate a decline of tuberculosis, but the results of our study showed that TB is still a serious disease that must comply with the first symptoms of tuberculosis in military personnel and their families that should be diagnosed as soon as possible.

  14. Cerebral venous thrombosis associated with homozygous factor V Leiden mutation in a 15-year-old girl of Tunisian origin.

    PubMed

    Salem-Berrabah, Olfa Ben; Fekih-Mrissa, Nejiba; Laayouni, Samy; Gritli, Nasreddine; Mrissa, Ridha

    2011-01-01

    Cerebral venous thrombosis (CVT) is a rare disease. It has numerous and complex etiologies. Inherited or acquired prothrombotic states play a key role in the development of this disease, such as factor V G1691A mutation (FV Leiden). A 15-year-old girl presented to the Department of Neurology with a complaint of severe headache with visual blurring. The diagnosis of CVT was not initially suspected because of the patient's condition on presentation. An MRI showed thrombosis in the superior sagittal sinus, confirming venous stroke. Anticardiolipin and antiphospholipid antibodies were assessed. In addition, inherited prothrombotic defects, such as protein C, protein S, and antithrombin deficiencies, and genetic mutations for FV Leiden, prothrombin gene G20210A (FII G20210A), and methyltetrahydrofolate reductase C677T (MTHFR C677T) were studied. All results were unremarkable except for the unique homozygous FV Leiden mutation, which likely contributed to this prothrombotic situation. This study highlights the fact that FV Leiden may play a significant role in the onset of CVT in young patients. PMID:22048515

  15. Gingival proliferative lesions in children and adolescents in Brazil: A 15-year-period cross-sectional study

    PubMed Central

    daSilva, Fabiana Caroline; Piazzetta, Cleto Mariosvaldo; Torres-Pereira, Cassius Carvalho; Schussel, Juliana Lucena; Amenábar, José Miguel

    2016-01-01

    Background: Studies assessing the prevalence of oral lesions in children and adolescents, particularly in gingiva are scarce in the literature. The aim of the study was to describe the distribution of gingival proliferative lesions based on clinical and histopathological diagnoses in children and adolescents. Materials and Methods: A review of clinical charts of children and adolescents aged between 0 and 18 years old, admitted to the Oral Medicine Outpatient Unit, of Universidade Federal do Paraná, for 15 years (1994–2009) was performed. Results: Six hundred and sixty-nine out of 5,129 patients treated during this period were aged between 0 and 18 years old, and 45 of these had gingival lesions. The largest number of lesions was observed between 11 and 16 years old. The majority of the patients were referred by Curitiba's public health system. Pyogenic granuloma was the most frequent lesion (19 = 42.2%), followed by peripheral giant cell lesion (11 = 24.4%), gingival fibromatosis (10 = 22.2%), and peripheral ossifying fibroma (5 = 11.1%). Conclusion: Gingival proliferative lesions can show similar clinical characteristics. Appropriate clinical and histopathological diagnoses are necessary to guide the healthcare professional to establish the adequate treatment and to estimate the risk of recurrence. PMID:27041840

  16. [Publishing--weighty characteristic of scientific productivity (analysis of scientific publications of 15-years period since Chernobyl catastrophe)].

    PubMed

    Bebeshko, V H; Bazyka, D A; Chumak, A A; Zapisochnyĭ, O Z

    2003-01-01

    We have carried out a complex analysis of scientific reports of the RCRM for the last 15-years since Chernobyl holocaust. One may notice considerable growth of circulation and quality coefficient of publication of scientific research. The tendency shape of the publications over a period of 1986-2001 looks like a straight line and dynamics of references on RCRM publications--an exponential curve. Degree of scientific effort connected with priority directions of the RCRM considerably exceed similar indices in the world. Studies of immunological and hematological irradiation effects, radiation shielding of population, radiation impact on a fetus and offspring are being carried out most intensively nowadays. The article highlights the innovations in the work of the center as a leading part of the research of the RCRM closely tied with the Chernobyl tragedy and its medical consequences, urgent need to improve and develop methodical and directive documents to make better health care management of Ukrainian people suffered from Chernobyl disaster. The above-mentioned consequences and accumulated experience of their resolution having global character, are not only important for Ukraine, but also have an international value.

  17. Concurrent little leaguer's elbow and shoulder in a 15-year-old baseball pitcher and football quarterback.

    PubMed

    Domes, Christopher M; Petering, Ryan C; Chesnutt, James C; Mirarchi, Adam

    2012-01-16

    Little leaguer's elbow and Little leaguer's shoulder are overuse pathologies seen in overhead-throwing athletes. No instance of simultaneously occurring pathologies has been published. A 15-year-old baseball pitcher and football quarterback developed pain in his throwing shoulder and elbow during spring baseball, which partially resolved with several months of rest. During fall football practice, he felt a pop and pain over his medial throwing elbow. Five days after the initial injury, medial elbow tenderness, mild swelling, and decreased range of motion were noted. Radiographs revealed a Salter I avulsion fracture of the medial humeral epicondyle (Little leaguer's elbow) and a periosteal reaction along the lateral aspect of the humeral metadiaphysis with slight widening (Little leaguer's shoulder). Surgical fixation of the medial epicondyle fracture and nonoperative treatment of the shoulder pathology were performed. Two-year follow-up radiographs showed a healed medial epicondylar fracture and resolution of the periosteal reaction of the humeral metadiaphysis. The patient returned to full activity and was starting quarterback for his football team. Biomechanical forces specific to overhead-throwing activities are associated with the development of Little leaguer's elbow and shoulder. Treatments of both pathologies remain controversial, with either initial operative vs nonoperative care. In this patient, a good outcome was achieved with surgical fixation of the elbow fracture and conservative management of the shoulder pathology. Educating coaches and parents on proper throwing technique and pitching limits should be the first step in reducing the occurrence of either pathology in this population.

  18. Fifteen Years of Collaborative Innovation and Achievement: NASA Nebraska Space Grant Consortium 15-Year Program Performance and Results Report

    NASA Technical Reports Server (NTRS)

    Schaaf, Michaela M. (Editor); Bowen, Brent D.; Fink, Mary M.; Nickerson, Jocelyn S.; Avery Shelly; Calamaio, Caprice; Carstenson, Larry; Dugan, James; Farr, Lynne; Farritor, Shane

    2003-01-01

    This 15-year evaluation serves as a summary document highlighting the numerous and complete successes of the Nebraska Space Grant Program. Innovation has been highlighted through significant new endeavors during this 5-year period, such as placement of students and faculty at NASA Centers and the expansion of NSGC Native American Outreach Programs. While the last national program evaluation resulted in Nebraska s ranking as the top Capability Enhancement Consortium, and 5th best overall, Nebraska felt there was room for significant growth and development. This has been validated through the recent competitive attainment of Designated Grant status and has allowed for the exploration of new initiatives, as well as the expansion of already successful programs. A comprehensive strategic planning effort has involved all Nebraska representative entities and has guided Nebraska Space Grant through the evaluation period, providing a basis for continual advancement. Nebraska rigorously employs evaluation techniques to ensure that stated outcomes and metrics are achieved and that weaknesses are identified and corrected. With this coordinated approach, Nebraska expects that the next 5 years will yield new opportunities for significant achievement. Nebraska Space Grant will embrace new national endeavors, including the integration of Pender Public Schools -Nebraska s NASA Explorer School, geospatial initiatives, and the National Student Satellite Program.

  19. Cerebral venous thrombosis associated with homozygous factor V Leiden mutation in a 15-year-old girl of Tunisian origin

    PubMed Central

    Salem-Berrabah, Olfa Ben; Fekih-Mrissa, Nejiba; Laayouni, Samy; Gritli, Nasreddine; Mrissa, Ridha

    2011-01-01

    Cerebral venous thrombosis (CVT) is a rare disease. It has numerous and complex etiologies. Inherited or acquired prothrombotic states play a key role in the development of this disease, such as factor V G1691A mutation (FV Leiden). A 15-year-old girl presented to the Department of Neurology with a complaint of severe headache with visual blurring. The diagnosis of CVT was not initially suspected because of the patient's condition on presentation. An MRI showed thrombosis in the superior sagittal sinus, confirming venous stroke. Anticardiolipin and antiphospholipid antibodies were assessed. In addition, inherited prothrombotic defects, such as protein C, protein S, and antithrombin deficiencies, and genetic mutations for FV Leiden, prothrombin gene G20210A (FII G20210A), and methyltetrahydrofolate reductase C677T (MTHFR C677T) were studied. All results were unremarkable except for the unique homozygous FV Leiden mutation, which likely contributed to this prothrombotic situation. This study highlights the fact that FV Leiden may play a significant role in the onset of CVT in young patients. PMID:22048515

  20. Dental caries status and oral health practice among 12-15 year old children in Jorpati, Kathmandu.

    PubMed

    Khanal, S; Acharya, J

    2014-09-01

    Oral health is an essential component of health throughout life. There has been a decline in dental caries and periodontal disease in developed countries which can be attributed to the implementation of preventive programmes but in developing countries dental diseases are still on the rise. Therefore this cross sectional study was carried out to assess the prevalence of dental caries and oral hygiene practices among 12 to 15 years old children. Self administered close ended questionnaires were used to assess the oral hygiene practice. The overall dental caries prevalence was 58.3% and the mean DMFT score was 1.2 (± 1.79) and the deft score was 0.6 (± 1.24). Majority of the children (84.1%) presented with the practice of brushing their teeth once everyday using tooth brush and toothpaste. Regular dental check up was very poor (5.6%) but 77.4% reported that they visited a dentist in case of pain or presence of stains in the teeth. Females (63.4%) and children studying in higher secondary class (74.2%) showed a "good" level of oral hygiene practice than males and children in secondary class respectively. Children having "good" practice presented with "low" dental caries severity. The utilization of dental services was poor in the children, therefore highlighting the necessity to implement preventive programmes is important which would help in reducing the incidence of the dental caries as well as aiding in prompt treatment of dental caries at its initial stages.

  1. Farm machinery injuries: the 15-year experience at an urban joint trauma center system in a rural state.

    PubMed

    Jawa, Randeep S; Young, David H; Stothert, Joseph C; Yetter, Diane; Dumond, Robbie; Shostrom, Valerie K; Cemaj, Samuel; Rautiainen, Risto H; Mercer, David W

    2013-01-01

    Farm machinery is a major source of injury. The objective of this study is to characterize the incidence, injury characteristics, and outcomes of patients admitted with farm machinery injuries (FMIs) to an urban joint trauma system in a rural state. A retrospective 15-year review of the trauma registries of the two trauma centers that function as a single state-designated Level I joint trauma center system was conducted. There were 65 admissions for FMIs at hospital A and 41 at hospital B; this represents under 0.4% of total trauma admissions. The patients ranged in age from 2 to 87 years. At hospital A, 89% of admitted patients sustained extremity injuries, 16% sustained torso trauma, 92% required surgical intervention, and the mortality rate was 0%. At hospital B, 60% of admitted patients sustained extremity injuries, 36.6% of patients sustained torso trauma, 63% required surgical intervention, and the mortality rate was 14.6%. Tractor-related injuries were responsible for 17% of admissions at hospital A and 69% at hospital B. Of the six fatalities, five were tractor related. The data demonstrate that FMIs affect people in nearly all decades of life. FMIs at the two hospitals had differing injury characteristics and outcomes, in large part secondary to the differing frequency of tractor-related injuries. FMIs frequently required surgical intervention. PMID:23540300

  2. Overview of the MISSE 7 Polymers and Zenith Polymers Experiments After 1.5 Years of Space Exposure

    NASA Technical Reports Server (NTRS)

    Yi, Grace T.; deGroh, Kim, K.; Banks, Bruce A.; Haloua, Athena; Imka, Emily C.; Mitchell, Gianna G.

    2013-01-01

    As part of the Materials International Space Station Experiment 7 (MISSE 7), two experiments called the Polymers Experiment and the Zenith Polymers Experiment were flown on the exterior of the International Space Station (ISS) and exposed to the low Earth orbit (LEO) space environment for 1.5 years. The Polymers Experiment contained 47 samples, which were flown in a ram or wake flight orientation. The objectives of the Polymers Experiment were to determine the LEO atomic oxygen erosion yield (Ey, volume loss per incident oxygen atoms, given in cu cm/atom) of the polymers, and to determine if atomic oxygen erosion of high and low ash containing polymers is dependent on fluence. The Zenith Polymers Experiment was flown in a zenith flight orientation. The primary objective of the Zenith Polymers Experiment was to determine the effect of solar exposure on the erosion of fluoropolymers. Kapton H (DuPont, Wilmington, DE) was flown in each experiment for atomic oxygen fluence determination. This paper provides an introduction to both the MISSE 7 Polymers Experiment and the MISSE 7 Zenith Polymers Experiment, and provides initial erosion yield results.

  3. Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.

    PubMed

    Wu, Xueling; Zhang, Zhenhai; Schramm, Chaim A; Joyce, M Gordon; Kwon, Young Do; Zhou, Tongqing; Sheng, Zizhang; Zhang, Baoshan; O'Dell, Sijy; McKee, Krisha; Georgiev, Ivelin S; Chuang, Gwo-Yu; Longo, Nancy S; Lynch, Rebecca M; Saunders, Kevin O; Soto, Cinque; Srivatsan, Sanjay; Yang, Yongping; Bailer, Robert T; Louder, Mark K; Mullikin, James C; Connors, Mark; Kwong, Peter D; Mascola, John R; Shapiro, Lawrence

    2015-04-23

    HIV-1-neutralizing antibodies develop in most HIV-1-infected individuals, although highly effective antibodies are generally observed only after years of chronic infection. Here, we characterize the rate of maturation and extent of diversity for the lineage that produced the broadly neutralizing antibody VRC01 through longitudinal sampling of peripheral B cell transcripts over 15 years and co-crystal structures of lineage members. Next-generation sequencing identified VRC01-lineage transcripts, which encompassed diverse antibodies organized into distinct phylogenetic clades. Prevalent clades maintained characteristic features of antigen recognition, though each evolved binding loops and disulfides that formed distinct recognition surfaces. Over the course of the study period, VRC01-lineage clades showed continuous evolution, with rates of ∼2 substitutions per 100 nucleotides per year, comparable to that of HIV-1 evolution. This high rate of antibody evolution provides a mechanism by which antibody lineages can achieve extraordinary diversity and, over years of chronic infection, develop effective HIV-1 neutralization. PMID:25865483

  4. Treatment of choledochal cyst in a pediatric population. A single institution experience of 15-years. Case series

    PubMed Central

    Silva-Baez, Hector; Coello-Ramírez, Pedro; Ixtabalán-Escalante, Eddy Mizraím; Sotelo-Anaya, Eduardo; Gallo-Morales, Mariana; Cordero-Estrada, Eduardo; Sainz-Escarrega, Victor Hugo; Ploneda-Valencia, César Felipe

    2015-01-01

    Background Choledochal cyst (CC) is a rare congenital anomaly of the bile duct that approximately 75% of the patients are diagnosed in childhood. Without a standardized surgical procedure for the biliary reconstruction, we present our experience over the last 15 years and show the differences between the biliary reconstructions techniques in our population. Methods We did a retrospective hospital archive search for patients admitted to the pediatric surgery department with the diagnosis of a choledochal cyst from January 2000 to June 2015. Results We found 15 patients, of which, 1 was excluded because of missing data from the hospital record. Of the remaining 14, eight had hepaticojejunal (HY) anastomosis in Roux-en-Y, with a 25% rate of complications; six had hepatoduodenal (HD) anastomosis with a rate of complications of 16.6%. The average hospital length of stay in the group of HD vs. HY was 14 ± 1.6-days vs. 19 ± 8.2-days respectively. Discussion There are no standardized surgical reconstruction techniques of the biliary tract after the CC excision, there is literature that supports the biliary reconstruction with an HY and an HD without a distinct advantage over one or the other. Conclusion: In our series HD anastomosis represents a safe procedure with fewer complications than HY. PMID:26900456

  5. Neurocognitive dysfunction and psychosocial outcome in patients with bipolar I disorder at 15-year follow-up

    PubMed Central

    Burdick, K. E.; Goldberg, J. F.; Harrow, M.

    2010-01-01

    Objective Despite increasing interest in cognitive dysfunction in bipolar disorder, little is known about its impact on functional outcome relative to affective symptoms. Method A total of 33 bipolar I subjects were evaluated at index hospitalization and prospectively followed up 15 years later. Affective symptoms, cognition, global functioning, work, and social adjustment were assessed at follow-up and analyzed by linear regression. Results Global functional impairment was significantly associated with poor performance on a cognitive measure of processing speed (WAIS Digit Symbol). Digit symbol performance also was the sole significant predictor of social functioning. Neither symptom severity nor course of illness features significantly contributed to global and social functioning. In contrast, verbal learning deficits, recent depression, and lifetime hospitalizations all were independently associated with work disability. Conclusion Processing speed is robustly associated with social and global functioning in bipolar disorder. Poor work functioning is significantly related to subsyndromal depression, course of illness, and verbal learning deficits. Cognitive and mood symptoms warrant consideration as independent determinants of functioning in patients with bipolar disorder many years after an index manic episode. PMID:20637012

  6. Seroprevalence of hepatitis a and associated factors among 1-15 year old children in Eastern Turkey

    PubMed Central

    Karaman, Serap; Karaman, Kamuran; Kızılyıldız, Baran Serdar; Ceylan, Nesrin; Kaba, Sultan; Parlak, Mehmet; Beger, Burhan; Ceylan, Abdullah

    2015-01-01

    Background: Hepatitis A is a common infectious disease during childhood worldwide. Recently, great deal of changes in the epidemiology has been reported. The seroepidemiologic studies of this infection are not sufficient in Eastern region of Turkey. Objective: To investigate the seroprevalence and association with socio-demographic variables of hepatitis A in 1-15 year old children in Van. Patients and Methods: This study was performed on 510 one to fifteen year old children from outpatient pediatric clinics in Yüzüncü Yıl University, Faculty of Medicine during last three months of 2009. Anti-HAV IgG was measured in sera by enzyme-linked immunosorbent assay. The information about subjects was recorded on standardized forms and a chart review survey was performed. Results: The overall ratio for seropositivity was 54.9%. Statistical significance was found between hepatitis A seroprevalence and age, collective use of domestic items, fresh water resources, localization and type of toilet and the number of households. Conclusion: This study provided the most recent data of seropositivity and revealed the preliminary indication of epidemiological shift in seroprevalence of Hepatitis A virus in a region with high endemicity. PMID:26770581

  7. Farm machinery injuries: the 15-year experience at an urban joint trauma center system in a rural state.

    PubMed

    Jawa, Randeep S; Young, David H; Stothert, Joseph C; Yetter, Diane; Dumond, Robbie; Shostrom, Valerie K; Cemaj, Samuel; Rautiainen, Risto H; Mercer, David W

    2013-01-01

    Farm machinery is a major source of injury. The objective of this study is to characterize the incidence, injury characteristics, and outcomes of patients admitted with farm machinery injuries (FMIs) to an urban joint trauma system in a rural state. A retrospective 15-year review of the trauma registries of the two trauma centers that function as a single state-designated Level I joint trauma center system was conducted. There were 65 admissions for FMIs at hospital A and 41 at hospital B; this represents under 0.4% of total trauma admissions. The patients ranged in age from 2 to 87 years. At hospital A, 89% of admitted patients sustained extremity injuries, 16% sustained torso trauma, 92% required surgical intervention, and the mortality rate was 0%. At hospital B, 60% of admitted patients sustained extremity injuries, 36.6% of patients sustained torso trauma, 63% required surgical intervention, and the mortality rate was 14.6%. Tractor-related injuries were responsible for 17% of admissions at hospital A and 69% at hospital B. Of the six fatalities, five were tractor related. The data demonstrate that FMIs affect people in nearly all decades of life. FMIs at the two hospitals had differing injury characteristics and outcomes, in large part secondary to the differing frequency of tractor-related injuries. FMIs frequently required surgical intervention.

  8. Effects of mountain beaver management and thinning on 15-year-old Douglas fir growth and survival.

    PubMed

    Campbell, Dan L; Engeman, Richard M; Farley, James P

    2015-07-01

    We examined 4-year growth of 15-year-old damaged and undamaged Douglas fir (Pseudotsuga menzesii) after integrating temporary population reductions of mountain beaver (Aplodontia rufa) with thinning in a pre-commercial hand-planted plantation in western Washington. Five treatment combinations were considered: (1) trapping mountain beavers in an unthinned area, (2) trapping before thinning to 65 trees/ha (160 trees/ac), (3) no trapping and thinning to 65 trees/ha, (4) no trapping and thinning to 146 trees/ha (360 trees/ac), and (5) no trapping and no thinning. Removal of ≥ 90 % of mountain beavers temporarily reduced mountain beaver activity whether the stand was unthinned or thinned. Diameter growth at breast height (dbh) was greater for undamaged trees than for damaged trees in thinned areas. Tree height growth was greatest in trapped areas whether thinned or not. No differences were detected in 4-year survival between trees damaged aboveground and those without aboveground damage, which may be related to undetected root damage to trees without aboveground damage. Basal diameter growth and dbh growth were greatest for areas thinned to 65 trees/ha. Seventy-eight percent of stomachs from mountain beaver trapped in winter contained Douglas fir root or stem materials. Overall, short-term removal of mountain beavers integrated with pre-commercial thinning promoted growth of crop trees.

  9. Assessment of the Dietary Intake of Schoolchildren in South Africa: 15 Years after the First National Study

    PubMed Central

    Steyn, Nelia; Eksteen, Gabriel; Senekal, Marjanne

    2016-01-01

    There has not been a national dietary study in children in South Africa since 1999. Fortification of flour and maize meal became mandatory in October 2003 to address micronutrient deficiencies found in the national study in 1999. The purpose of this review was to identify studies done after 1999 in schoolchildren, 6–15 years old, in order to determine whether dietary intakes reflected improvements in micronutrients, namely: iron, zinc, vitamin A, folate, thiamine, riboflavin, vitamin B6, and niacin. An electronic and hand search was done to identify all studies complying with relevant inclusion criteria. The search yielded 10 studies. Overall, there is a paucity of dietary studies which have included the fortified nutrients; only four, of which only one, reported on all micronutrients; making it difficult to determine whether fortification has improved the micronutrient intake of schoolchildren. This is further complicated by the fact that different dietary methods were used and that studies were only done in three of the nine provinces and thus are not generalizable. The results of these studies clearly point to the importance of doing a national study on the dietary intake of schoolchildren in order to confirm the outcomes of the fortification process. PMID:27548214

  10. Vocations as a source of identity: reciprocal relations between Big Five personality traits and RIASEC characteristics over 15 years.

    PubMed

    Wille, Bart; De Fruyt, Filip

    2014-03-01

    Although work is a core part of life, the direction of influence from personality to work has typically been conceived as only unidirectional. The present study aims to contribute to the literature by considering reciprocal relations between personality and occupational characteristics, drawing on current perspectives from personality psychology (i.e., the social investment principle) and using a well-established framework to conceptualize career development (i.e., Holland's RIASEC theory). For this purpose, a longitudinal cohort of college alumni (N = 266) was tracked across a substantial and significant period in their professional career. Big Five personality traits and RIASEC occupational characteristics were assessed at the career start and 15 years later when their careers had unfolded. A combination of observed and latent variable analyses were used to disentangle the longitudinal and reciprocal relations between traits and occupational characteristics. Our results indicate that personality shapes and is shaped by our vocational experiences, suggesting that work can be a source of identity. The implications for theory and research on personality in the industrial and organizational literature are discussed alongside a number of practical implications for organizational and counseling settings.

  11. Effects of mountain beaver management and thinning on 15-year-old Douglas fir growth and survival.

    PubMed

    Campbell, Dan L; Engeman, Richard M; Farley, James P

    2015-07-01

    We examined 4-year growth of 15-year-old damaged and undamaged Douglas fir (Pseudotsuga menzesii) after integrating temporary population reductions of mountain beaver (Aplodontia rufa) with thinning in a pre-commercial hand-planted plantation in western Washington. Five treatment combinations were considered: (1) trapping mountain beavers in an unthinned area, (2) trapping before thinning to 65 trees/ha (160 trees/ac), (3) no trapping and thinning to 65 trees/ha, (4) no trapping and thinning to 146 trees/ha (360 trees/ac), and (5) no trapping and no thinning. Removal of ≥ 90 % of mountain beavers temporarily reduced mountain beaver activity whether the stand was unthinned or thinned. Diameter growth at breast height (dbh) was greater for undamaged trees than for damaged trees in thinned areas. Tree height growth was greatest in trapped areas whether thinned or not. No differences were detected in 4-year survival between trees damaged aboveground and those without aboveground damage, which may be related to undetected root damage to trees without aboveground damage. Basal diameter growth and dbh growth were greatest for areas thinned to 65 trees/ha. Seventy-eight percent of stomachs from mountain beaver trapped in winter contained Douglas fir root or stem materials. Overall, short-term removal of mountain beavers integrated with pre-commercial thinning promoted growth of crop trees. PMID:25772877

  12. Assessment of the Dietary Intake of Schoolchildren in South Africa: 15 Years after the First National Study.

    PubMed

    Steyn, Nelia; Eksteen, Gabriel; Senekal, Marjanne

    2016-01-01

    There has not been a national dietary study in children in South Africa since 1999. Fortification of flour and maize meal became mandatory in October 2003 to address micronutrient deficiencies found in the national study in 1999. The purpose of this review was to identify studies done after 1999 in schoolchildren, 6-15 years old, in order to determine whether dietary intakes reflected improvements in micronutrients, namely: iron, zinc, vitamin A, folate, thiamine, riboflavin, vitamin B6, and niacin. An electronic and hand search was done to identify all studies complying with relevant inclusion criteria. The search yielded 10 studies. Overall, there is a paucity of dietary studies which have included the fortified nutrients; only four, of which only one, reported on all micronutrients; making it difficult to determine whether fortification has improved the micronutrient intake of schoolchildren. This is further complicated by the fact that different dietary methods were used and that studies were only done in three of the nine provinces and thus are not generalizable. The results of these studies clearly point to the importance of doing a national study on the dietary intake of schoolchildren in order to confirm the outcomes of the fortification process. PMID:27548214

  13. Vibration of x-braced portal frames

    NASA Astrophysics Data System (ADS)

    Chang, C. H.; Wang, P. Y.; Lin, Y. W.

    1987-09-01

    Both free and forced vibrations of elastic X-braced portal frames are investigated. Solutions of the Euler-Bernoulli equation for the transverse vibration coupled with the axial vibration are used. The first five natural frequencies, with the angle of inclination, α, of the bracing bars ranging from 15° to 75°, with different slenderness ratios, R, of the columns, and different stiffness of the floor beam and crossing bars, are presented along with two sets of the natural modes of the frames with α = 45°. For the forced vibration, the dynamic responses of the frames with a concentrated horizontal time dependent force acting at a top joint are studied. The responses of the frames with α = 45° are analyzed in detail.

  14. A Logistic Regression Analysis of Turkey's 15-Year-Olds' Scoring above the OECD Average on the PISA'09 Reading Assessment

    ERIC Educational Resources Information Center

    Kasapoglu, Koray

    2014-01-01

    This study aims to investigate which factors are associated with Turkey's 15-year-olds' scoring above the OECD average (493) on the PISA'09 reading assessment. Collected from a total of 4,996 15-year-old students from Turkey, data were analyzed by logistic regression analysis in order to model the data of students who were split…

  15. Transitions in students' epistemic framing along two axes

    NASA Astrophysics Data System (ADS)

    Irving, Paul W.; Martinuk, Mathew Sandy; Sayre, Eleanor C.

    2013-06-01

    We use epistemological framing to interpret participants’ behavior during group problem-solving sessions in an intermediate mechanics course. We are interested in how students frame discussion and in how the groups shift discussion framings. Our analysis includes two framing axes, expansive vs narrow and serious vs silly, which together incorporate and extend prior work on how students frame discussions in physics education research. We present markers for where discussion falls on these axes. We support our conclusions with both microanalytic excerpts of discussion and overall analysis of 75 hours of video-based data. We find that the group spends most of its time in more serious framings, and slightly more than half of its time in more narrow ones. The teaching assistant is the participant who initiates the largest number of frame shifts, and her shifts include bids to all quadrants in the expansive or narrow and serious or silly plane.

  16. The fully non-linear post-Friedmann frame-dragging vector potential: magnitude and time evolution from N-body simulations

    NASA Astrophysics Data System (ADS)

    Thomas, Daniel B.; Bruni, Marco; Wands, David

    2015-09-01

    Newtonian simulations are routinely used to examine the matter dynamics on non-linear scales. However, even on these scales, Newtonian gravity is not a complete description of gravitational effects. A post-Friedmann approach shows that the leading-order correction to Newtonian theory is a vector potential in the metric. This vector potential can be calculated from N-body simulations, requiring a method for extracting the velocity field. Here, we present the full details of our calculation of the post-Friedmann vector potential, using the Delaunay Tessellation Field Estimator code. We include a detailed examination of the robustness of our numerical result, including the effects of box size and mass resolution on the extracted fields. We present the power spectrum of the vector potential and find that the power spectrum of the vector potential is ˜105 times smaller than the power spectrum of the fully non-linear scalar gravitational potential at redshift zero. Comparing our numerical results to perturbative estimates, we find that the fully non-linear result can be more than an order of magnitude larger than the perturbative estimate on small scales. We extend the analysis of the vector potential to multiple redshifts, showing that this ratio persists over a range of scales and redshifts. We also comment on the implications of our results for the validity and interpretation of Newtonian simulations.

  17. Conformal frame dependence of inflation

    SciTech Connect

    Domènech, Guillem; Sasaki, Misao E-mail: misao@yukawa.kyoto-u.ac.jp

    2015-04-01

    Physical equivalence between different conformal frames in scalar-tensor theory of gravity is a known fact. However, assuming that matter minimally couples to the metric of a particular frame, which we call the matter Jordan frame, the matter point of view of the universe may vary from frame to frame. Thus, there is a clear distinction between gravitational sector (curvature and scalar field) and matter sector. In this paper, focusing on a simple power-law inflation model in the Einstein frame, two examples are considered; a super-inflationary and a bouncing universe Jordan frames. Then we consider a spectator curvaton minimally coupled to a Jordan frame, and compute its contribution to the curvature perturbation power spectrum. In these specific examples, we find a blue tilt at short scales for the super-inflationary case, and a blue tilt at large scales for the bouncing case.

  18. A greigite-based magnetostratigraphic time frame for the Late Miocene to Recent DSDP Leg 42B cores from the Black Sea

    NASA Astrophysics Data System (ADS)

    van Baak, Christiaan; Vasiliev, Iuliana; Palcu, Dan; Dekkers, Mark; Krijgsman, Wout

    2016-04-01

    In 1975, during DSDP Leg 42B to the Black Sea, three sites were drilled with a total of 2318 m cored and a recovery of 55%. While to modern scientific standards this may not be very impressive, these sites still represent the longest available records of sedimentation in the basinal part of the Black Sea. The main stratigraphic objectives of DSDP Leg 42B were to 1) obtain a complete Pleistocene litho- and biostratigraphic section and 2) study interactions between the Black Sea and Mediterranean Sea, focusing on glacio-eustatic sea level change, periods of lacustrine sedimentation, periods of anoxia, and 3) to establish a paleoclimatic record. Major problems establishing a timescale emerged after drilling due to a) the general shortage of definitive paleontological age markers and b) the general lack of agreement on correlation and time zonation of sedimentary units. Magnetostratigraphic dating could have solved these timescale problems but was hindered by the presence of the little understood authigenic iron sulphide mineral greigite (Fe3S4) as main magnetic carrier. In recent years, the understanding of greigite has significantly improved and is considered a reliable magnetic carrier. Especially in the circum-Black Sea region, many Miocene to recent, land-based sections are magnetostratigraphically dated with greigite as magnetic carrier. We therefore resampled the cores of DSDP Leg 42B to see whether after 40 years of storage any of the original signal is preserved. Our results show these cores are still surprisingly useful for magnetostratigraphic dating. Complications arise due to the presence of hiatuses, especially in the near-Bosporus locations. Our age model gives important new insights into the response of the Black Sea to major paleoenvironmental and climatic changes related to the late Miocene Messinian salinity crisis and throughout the Pleistocene. More generally, our results show that for future deep-sea drilling expeditions to the Black Sea, the

  19. Greigite-based magnetostratigraphic framework for the Late Miocene to recent DSDP Leg 42B cores from the Black Sea: A new time frame for old cores

    NASA Astrophysics Data System (ADS)

    Baak, C. V.; Vasiliev, I.; Grothe, A.; Kuiper, K.; Raffi, I.; Krijgsman, W.

    2014-12-01

    In 1975, DSDP Leg 42B to the Black Sea, three sites were drilled with a total of 2318 m cored and a recovery of 55%. While to modern standards this may not be very impressive, these sites still represent the best record of sedimentation in the basinal part of the Black Sea. The main stratigraphic objectives of DSDP Leg 42B were to 1) obtain a complete Pleistocene litho- and biostratigraphic section and 2) study interactions between the Black Sea and Mediterranean Sea, focusing on glacio-eustatic sea level change, periods of lacustrine sedimentation, periods of stagnation, and to establish a paleoclimatic record. Major problems establishing a timescale emerged after drilling due to a) the general shortage of definitive paleontological age markers and b) the general lack of agreement on correlation and time zonation of sedimentary units. Magnetostratigraphic dating could have solved these timescale problems but was hindered by the presence of the little understood authigenic iron sulphide mineral greigite (Fe3S4) as main magnetic carrier. In recent years, the understanding of greigite has significantly improved and is considered a reliable magnetic carrier. Especially in the circum-Black Sea region, many Miocene to recent, land-based sections are magnetostratigraphically dated with greigite as magnetic carrier. We therefore resample the cores of DSDP Leg 42B to see whether after 40 years of storage any of the original signal is preserved. Our results show these cores are surprisingly useful for magnetostratigraphic dating. We create an integrated bio-magnetostratigraphic framework for the sites of Leg 42B, focusing on the Latest Miocene and Plio-Pleistocene. Ar/Ar dating of an ash-layer at site 380A gives additional age constraints. Our age model gives important new insights into the response of the Black Sea to major paleoenvironmental and climatic changes like e.g. the Messinian salinity crisis, the mid-Pliocene warm period and Pleistocene glaciations on the

  20. Socioeconomic and geographic inequalities in adolescent smoking: A multilevel cross-sectional study of 15 year olds in Scotland

    PubMed Central

    Levin, K.A.; Dundas, R.; Miller, M.; McCartney, G.

    2014-01-01

    The objective of the study was to present socioeconomic and geographic inequalities in adolescent smoking in Scotland. The international literature suggests there is no obvious pattern in the geography of adolescent smoking, with rural areas having a higher prevalence than urban areas in some countries, and a lower prevalence in others. These differences are most likely due to substantive differences in rurality between countries in terms of their social, built and cultural geography. Previous studies in the UK have shown an association between lower socioeconomic status and smoking. The Scottish Health Behaviour in School-aged Children study surveyed 15 year olds in schools across Scotland between March and June of 2010. We ran multilevel logistic regressions using Markov chain Monte Carlo method and adjusting for age, school type, family affluence, area level deprivation and rurality. We imputed missing rurality and deprivation data using multivariate imputation by chained equations, and re-analysed the data (N = 3577), comparing findings. Among boys, smoking was associated only with area-level deprivation. This relationship appeared to have a quadratic S-shape, with those living in the second most deprived quintile having highest odds of smoking. Among girls, however, odds of smoking increased with deprivation at individual and area-level, with an approximate dose–response relationship for both. Odds of smoking were higher for girls living in remote and rural parts of Scotland than for those living in urban areas. Schools in rural areas were no more or less homogenous than schools in urban areas in terms of smoking prevalence. We discuss possible social and cultural explanations for the high prevalence of boys' and girls' smoking in low SES neighbourhoods and of girls' smoking in rural areas. We consider possible differences in the impact of recent tobacco policy changes, primary socialization, access and availability, retail outlet density and the home

  1. Dental pain among 10–15 year old children attending oral health promoting schools: A cross-sectional study

    PubMed Central

    Saheer, Abdul; Kousalya, Pallavi Swami; Raju, Rekha; Gubbihal, Radha

    2015-01-01

    Introduction: Dental pain is a major public health problem and one of the consequences of oral diseases which requires significant adjustments in life management leading to decreased quality of life. Objective: To assess prevalence of dental pain and its impact on daily life and to explore its relationship with oral health behavior and clinical oral status among 10-15 year old school children attending oral health promoting schools. Method: This cross sectional study was conducted in 6 schools serving low -middle socio economic strata in Bangalore, India. A total of 1237 children were surveyed for history of dental pain during past 3 month. Participants who reported dental pain completed self-reported oral health behaviour and Child dental pain questionnaire. Clinical oral examination included assessment of dental caries, periodontal status. Data was analyzed using t - test, Chi-square test, ANOVA and Regression Analysis. Results: Prevalence of dental pain was 15.6% (n = 194). Among children with pain, 17%, 43% and 40% reported mild, moderate and severe pain. Impact on daily activities was reported by 66%. Mean DMFT and DMFS was 1.80 and 2.11 Mean deft and defs was 2.47 and 3.41. Multiple logistic regression revealed that severity and impact of dental pain was associated with gender, frequency of tooth brushing, consumption of sweets and deciduous dental caries experience. Conclusion: Prevalence of Dental pain is associated with brushing behavior, consumption of sweets and deciduous dental caries experience, showing need for further attention to these conditions and a need to strengthen preventive and therapeutic dental services. PMID:26942112

  2. Socioeconomic and geographic inequalities in adolescent smoking: a multilevel cross-sectional study of 15 year olds in Scotland.

    PubMed

    Levin, K A; Dundas, R; Miller, M; McCartney, G

    2014-04-01

    The objective of the study was to present socioeconomic and geographic inequalities in adolescent smoking in Scotland. The international literature suggests there is no obvious pattern in the geography of adolescent smoking, with rural areas having a higher prevalence than urban areas in some countries, and a lower prevalence in others. These differences are most likely due to substantive differences in rurality between countries in terms of their social, built and cultural geography. Previous studies in the UK have shown an association between lower socioeconomic status and smoking. The Scottish Health Behaviour in School-aged Children study surveyed 15 year olds in schools across Scotland between March and June of 2010. We ran multilevel logistic regressions using Markov chain Monte Carlo method and adjusting for age, school type, family affluence, area level deprivation and rurality. We imputed missing rurality and deprivation data using multivariate imputation by chained equations, and re-analysed the data (N = 3577), comparing findings. Among boys, smoking was associated only with area-level deprivation. This relationship appeared to have a quadratic S-shape, with those living in the second most deprived quintile having highest odds of smoking. Among girls, however, odds of smoking increased with deprivation at individual and area-level, with an approximate dose-response relationship for both. Odds of smoking were higher for girls living in remote and rural parts of Scotland than for those living in urban areas. Schools in rural areas were no more or less homogenous than schools in urban areas in terms of smoking prevalence. We discuss possible social and cultural explanations for the high prevalence of boys' and girls' smoking in low SES neighbourhoods and of girls' smoking in rural areas. We consider possible differences in the impact of recent tobacco policy changes, primary socialization, access and availability, retail outlet density and the home

  3. Colonic polyposis in a 15 year-old boy: Challenges and lessons from a rural resource-poor area

    PubMed Central

    Kakembo, Nasser; Kisa, Phyllis; Fitzgerald, Tamara; Ozgediz, Doruk; Sekabira, John

    2016-01-01

    Introduction Colorectal polyps usually present with rectal bleeding and are associated with increased risk of colorectal carcinoma. Evaluation and management in resource-poor areas present unique challenges. Presentation of case This 15 year-old boy presented with 9 years of painless rectal bleeding and 2 years of a prolapsing rectal mass after passing stool. He had 3 nephews with similar symptoms. On clinical assessment and initial exam under anesthesia, an impression of a polyposis syndrome was made and a biopsy taken from the mass that revealed inflammatory polyps with no dysplasia. He was identified during a pediatric surgical outreach to a rural area with no endoscopy, limited surgical services, and no genetic testing available, even at a tertiary center. He subsequently had a three-stage proctocolectomy and ileal pouch anal anastomosis with good outcome after referral to a tertiary care center. The surgical specimen showed many polyps scattered through the colon. Discussion In the absence of endoscopic surveillance and diagnostic services including advanced pathology and genetic testing, colorectal polyposis syndromes are a significant challenge if encountered in these settings. Reports from similar settings have not included this surgical treatment, often opting for partial colectomy. Nonetheless, good outcomes can be achieved even given these constraints. The case also illustrates the complexity of untreated chronic pediatric surgical disease in rural resource-poor areas with limited health care access. Conclusion Polyposis syndromes in children present unique challenges in rural resource-poor settings. Good outcomes can be achieved with total proctocolectomy and ileal pouch anastomosis. PMID:27144002

  4. Long-term outcome after liver transplantation for hepatic schistosomiasis: a single-center experience over 15 years.

    PubMed

    El Moghazy, Walid; Kashkoush, Samy; O'hali, Wael; Abdallah, Khalid

    2015-01-01

    Our objective was to study the long-term outcomes of patients who had undergone liver transplantation because of schistosomiasis at our institute over the last 15 years. Four hundred forty-one patients underwent liver transplantation at our institute, and 14 did so for schistosomiasis. The survival of patients who underwent transplantation for schistosomiasis was compared with that of patients who underwent transplantation for other liver diseases. Survival curves were drawn via the Kaplan-Meier method and were compared with the log-rank test. P < 0.05 was considered significant. All 14 patients were male, and the average age was 56.8 ± 8.4 years. The average Model for End-Stage Liver Disease score was 18.2 ± 5.6, and the average Child-Pugh score was 10.6 ± 1.2. All patients had splenomegaly; pretransplant variceal bleeding occurred in 7 patients (50%), and portal vein thrombosis was diagnosed in 5 patients (36%). Patient survival was 75% 1 year after transplantation and 75% at the end of follow-up because no patients were lost after the first year. Patients who underwent transplantation for other causes achieved survival rates of 86% and 76% 1 and 10 years after transplantation, respectively. There was no significant survival difference between the 2 groups (P = 0.66). All patients who survived the early posttransplant period had functioning liver grafts with no reported diagnoses of schistosomiasis in the new grafts. In conclusion, liver transplantation for patients with schistosomiasis has a favorable outcome with no risk of reactivation.

  5. Prevalence of the developmental defects of the enamel in children aged 12–15 years in Kollam district

    PubMed Central

    Ravindran, Rathy; Saji, Ajish M.

    2016-01-01

    Aim and Objectives: To determine the prevalence of developmental defects of enamel in children aged 12–15 years in Kollam district and to examine the etiological factors associated with the developmental defects of the enamel (DDE). Materials and Methods: A total of 2,500 children from 10 urban and 10 rural schools were examined using modified DDE criteria for recording enamel defects. Ten index permanent teeth were screened for the DDE. Results: The overall prevalence of the DDE was found to be 32% and the prevalence is higher in urban schools (34.3%) compared to rural schools (29.6%). The most common tooth affected by the defect was maxillary right lateral incisor (P = 28.6%) and the tooth least affected was maxillary right first premolar (P = 3%). The most common deformity was demarcated opacities (P = 28.76%) and the least common deformity was combination of diffuse opacities and hypoplasia and combination of demarcated, diffuse opacities, and hypoplasia (P = 0%). There was a very high significant association between DDE and the mothers’ pregnancy age, illness during pregnancy for mother, medication taken during pregnancy by mother, prematurity of birth, intubation done during prematurity, birth weight, systemic illness during the first 5 years of life, intake of drugs or chemicals during the first 5 years of life, nutritional status, and trauma or infection on deciduous teeth and dental caries. Conclusions: The study population showed a prevalence of 32% and very high significant association between perinatal, natal, and postnatal etiological factors. It indicates the need for educating the population about the risk factors for the DDE. PMID:27011929

  6. VIOLENT FRAMES IN ACTION

    SciTech Connect

    Sanfilippo, Antonio P.; McGrath, Liam R.; Whitney, Paul D.

    2011-11-17

    We present a computational approach to radical rhetoric that leverages the co-expression of rhetoric and action features in discourse to identify violent intent. The approach combines text mining and machine learning techniques with insights from Frame Analysis and theories that explain the emergence of violence in terms of moral disengagement, the violation of sacred values and social isolation in order to build computational models that identify messages from terrorist sources and estimate their proximity to an attack. We discuss a specific application of this approach to a body of documents from and about radical and terrorist groups in the Middle East and present the results achieved.

  7. The Levels of Visual Framing

    ERIC Educational Resources Information Center

    Rodriguez, Lulu; Dimitrova, Daniela V.

    2011-01-01

    While framing research has centered mostly on the evaluations of media texts, visual news discourse has remained relatively unexamined. This study surveys the visual framing techniques and methods employed in previous studies and proposes a four-tiered model of identifying and analyzing visual frames: (1) visuals as denotative systems, (2) visuals…

  8. Clinical outcome study and radiological findings of Zweymuller metal on metal total hip arthroplasty. a follow-up of 6 to 15 years.

    PubMed

    Paleochorlidis, Ilias S; Badras, Leonidas S; Skretas, Efstathios F; Georgaklis, Vasilios A; Karachalios, Theofilos S; Malizos, Konstantinos N

    2009-01-01

    We report the clinical and radiological outcome of 99 Zweymuller metal on metal total hip arthroplasties in 84 patients followed up prospectively for a mean period of 9.5 (range, 6-15) years. There were 29 (34.5%) male and 55 (65.5%) female patients with a mean age of 62.85 years (range, 50-70 years) at the time of surgery. All patients had osteoarthritis. One acetabular component and one stem were revised due to aseptic loosening. One femoral stem was revised due to a periprosthetic fracture. HHS score improved from a preoperative mean of 62.56 points (SD 8.87) to a final postoperative follow-up mean of 93.48 (SD 7.7). Cumulative success rate for both implants at 13 years, with aseptic loosening as the end point, was 97.05%, while for both implants at 13 years, with revision for any reason as the end point, it was 91.17%. Satisfactory results were observed with the use of this prosthesis. PMID:20041375

  9. Aluminum and silica in drinking water and the risk of Alzheimer's disease or cognitive decline: findings from 15-year follow-up of the PAQUID cohort.

    PubMed

    Rondeau, Virginie; Jacqmin-Gadda, Hélène; Commenges, Daniel; Helmer, Catherine; Dartigues, Jean-François

    2009-02-15

    The authors examined associations between exposure to aluminum or silica from drinking water and risk of cognitive decline, dementia, and Alzheimer's disease among elderly subjects followed for 15 years (1988-2003). They actively searched for incident cases of dementia among persons aged 65 years or over living in 91 civil drinking-water areas in southern France. Two measures of exposure to aluminum were assessed: geographic exposure and individual exposure, taking into account daily consumption of tap water and bottled water. A total of 1,925 subjects who were free of dementia at baseline and had reliable water assessment data were analyzed. Using random-effects models, the authors found that cognitive decline with time was greater in subjects with a higher daily intake of aluminum from drinking water (>or=0.1 mg/day, P=0.005) or higher geographic exposure to aluminum. Using a Cox model, a high daily intake of aluminum was significantly associated with increased risk of dementia. Conversely, an increase of 10 mg/day in silica intake was associated with a reduced risk of dementia (adjusted relative risk =0.89, P=0.036). However, geographic exposure to aluminum or silica from tap water was not associated with dementia. High consumption of aluminum from drinking water may be a risk factor for Alzheimer's disease.

  10. OVERWEIGHT, OBESITY AND ASSOCIATED FACTORS AMONG 13-15 YEARS OLD STUDENTS IN THE ASSOCIATION OF SOUTHEAST ASIAN NATIONS MEMBER COUNTRIES, 2007-2014.

    PubMed

    Pengpid, Supa; Peltzer, Karl

    2016-03-01

    The aim of this study was to assess overweight or obesity and associated factors in school-going adolescents in the Association of Southeast Asian Nations (ASEAN) member countries. The analysis included 30,284 school children 13-15 years of age from seven ASEAN members participating in the Global School-based Student Health Survey (GSHS) between 2007 and 2013. The overall prevalence of overweight or obesity across seven ASEAN countries (excluding Brunei) was 9.9%, significantly higher in boys (11.5%) than in girls (8.3%). Among eight ASEAN countries, the highest prevalence of overweight or obesity was in Brunei Darus-salam (36.1%), followed by Malaysia (23.7%), and the lowest was in Myanmar (3.4%) and Cambodia (3.7%). Multivariate logistic regression analysis found that younger age, coming from an upper middle country, never been hungry, and not walking or biking to school were associated with overweight or obesity. In addition, among boys, having three or more servings of vegetables per day and having no close friends, and among girls, having fast foods two or more times per week, been victims of bullying and having peer support were additional factors associated with overweight or obesity. Increased strategies utilizing a number of the risk factors identified are needed to prevent and treat overweight or obesity in adolescents in ASEAN member countries. PMID:27244964

  11. OVERWEIGHT, OBESITY AND ASSOCIATED FACTORS AMONG 13-15 YEARS OLD STUDENTS IN THE ASSOCIATION OF SOUTHEAST ASIAN NATIONS MEMBER COUNTRIES, 2007-2014.

    PubMed

    Pengpid, Supa; Peltzer, Karl

    2016-03-01

    The aim of this study was to assess overweight or obesity and associated factors in school-going adolescents in the Association of Southeast Asian Nations (ASEAN) member countries. The analysis included 30,284 school children 13-15 years of age from seven ASEAN members participating in the Global School-based Student Health Survey (GSHS) between 2007 and 2013. The overall prevalence of overweight or obesity across seven ASEAN countries (excluding Brunei) was 9.9%, significantly higher in boys (11.5%) than in girls (8.3%). Among eight ASEAN countries, the highest prevalence of overweight or obesity was in Brunei Darus-salam (36.1%), followed by Malaysia (23.7%), and the lowest was in Myanmar (3.4%) and Cambodia (3.7%). Multivariate logistic regression analysis found that younger age, coming from an upper middle country, never been hungry, and not walking or biking to school were associated with overweight or obesity. In addition, among boys, having three or more servings of vegetables per day and having no close friends, and among girls, having fast foods two or more times per week, been victims of bullying and having peer support were additional factors associated with overweight or obesity. Increased strategies utilizing a number of the risk factors identified are needed to prevent and treat overweight or obesity in adolescents in ASEAN member countries.

  12. Cognitive framing in action.

    PubMed

    Huhn, John M; Potts, Cory Adam; Rosenbaum, David A

    2016-06-01

    Cognitive framing effects have been widely reported in higher-level decision-making and have been ascribed to rules of thumb for quick thinking. No such demonstrations have been reported for physical action, as far as we know, but they would be expected if cognition for physical action is fundamentally similar to cognition for higher-level decision-making. To test for such effects, we asked participants to reach for a horizontally-oriented pipe to move it from one height to another while turning the pipe 180° to bring one end (the "business end") to a target on the left or right. From a physical perspective, participants could have always rotated the pipe in the same angular direction no matter which end was the business end; a given participant could have always turned the pipe clockwise or counter-clockwise. Instead, our participants turned the business end counter-clockwise for left targets and clockwise for right targets. Thus, the way the identical physical task was framed altered the way it was performed. This finding is consistent with the hypothesis that cognition for physical action is fundamentally similar to cognition for higher-level decision-making. A tantalizing possibility is that higher-level decision heuristics have roots in the control of physical action, a hypothesis that accords with embodied views of cognition. PMID:26970853

  13. High Performance Commercial Fenestration Framing Systems

    SciTech Connect

    Mike Manteghi; Sneh Kumar; Joshua Early; Bhaskar Adusumalli

    2010-01-31

    A major objective of the U.S. Department of Energy is to have a zero energy commercial building by the year 2025. Windows have a major influence on the energy performance of the building envelope as they control over 55% of building energy load, and represent one important area where technologies can be developed to save energy. Aluminum framing systems are used in over 80% of commercial fenestration products (i.e. windows, curtain walls, store fronts, etc.). Aluminum framing systems are often required in commercial buildings because of their inherent good structural properties and long service life, which is required from commercial and architectural frames. At the same time, they are lightweight and durable, requiring very little maintenance, and offer design flexibility. An additional benefit of aluminum framing systems is their relatively low cost and easy manufacturability. Aluminum, being an easily recyclable material, also offers sustainable features. However, from energy efficiency point of view, aluminum frames have lower thermal performance due to the very high thermal conductivity of aluminum. Fenestration systems constructed of aluminum alloys therefore have lower performance in terms of being effective barrier to energy transfer (heat loss or gain). Despite the lower energy performance, aluminum is the choice material for commercial framing systems and dominates the commercial/architectural fenestration market because of the reasons mentioned above. In addition, there is no other cost effective and energy efficient replacement material available to take place of aluminum in the commercial/architectural market. Hence it is imperative to improve the performance of aluminum framing system to improve the energy performance of commercial fenestration system and in turn reduce the energy consumption of commercial building and achieve zero energy building by 2025. The objective of this project was to develop high performance, energy efficient commercial

  14. Frame architecture for video servers

    NASA Astrophysics Data System (ADS)

    Venkatramani, Chitra; Kienzle, Martin G.

    1999-11-01

    Video is inherently frame-oriented and most applications such as commercial video processing require to manipulate video in terms of frames. However, typical video servers treat videos as byte streams and perform random access based on approximate byte offsets to be supplied by the client. They do not provide frame or timecode oriented API which is essential for many applications. This paper describes a frame-oriented architecture for video servers. It also describes the implementation in the context of IBM's VideoCharger server. The later part of the paper describes an application that uses the frame architecture and provides fast and slow-motion scanning capabilities to the server.

  15. Intelligence's likelihood and evolutionary time frame

    NASA Astrophysics Data System (ADS)

    Bogonovich, Marc

    2011-04-01

    This paper outlines hypotheses relevant to the evolution of intelligent life and encephalization in the Phanerozoic. If general principles are inferable from patterns of Earth life, implications could be drawn for astrobiology. Many of the outlined hypotheses, relevant data, and associated evolutionary and ecological theory are not frequently cited in astrobiological journals. Thus opportunity exists to evaluate reviewed hypotheses with an astrobiological perspective. A quantitative method is presented for testing one of the reviewed hypotheses (hypothesis i; the diffusion hypothesis). Questions are presented throughout, which illustrate that the question of intelligent life's likelihood can be expressed as multiple, broadly ranging, more tractable questions.

  16. Assessment of Mandibular Movements in 10 to 15 Year-old Patients With and Without Temporomandibular Disorders.

    PubMed

    Cortese, Silvina G; Biondi, Ana M; Fridman, Diana E; Guitelman, Ingrid; Farah, Catalina L

    2015-12-01

    The aim of this study was to establish reference values for mandibular movements in 10- to 15-year-olds without dysfunction and compare these values to those in patients of the same age with tempromandibular disorders (TMD) and those found previously in a group of children younger than 11 years old without TMD. Children of both genders who visited the Department of Comprehensive Pediatric Dentistry at Buenos Aires University in 2013 and whose parents or guardians provided consent were evaluated using TMD/RDC by standardized pediatric dentists (Kappa 0.88). Three groups were formed according to diagnostic summary: Group C, without TMD; Group Ia, with myofascial pain, and Group Ib, pain with limited mouth opening. The following variables were analyzed: age, gender and mandibular movements. The sample included 169 patients aged 12.5±1.76 years, of whom 62.36% did not have TMD (C) while 37.27% were diagnosed with muscle disorder (29.58% Ia and 7.69% Ib). For Group C, the following values (in mm) were recorded: maximal unassisted opening: 48.28±6.14; right lateral movement 8.78±2.50; left lateral movement: 9.60±2.64; protrusion: 4.94±2.58 and overbite: 2.98 ± 2.5, with no variation associated to sex, but with differences in the values recorded for all movements compared to those obtained for mixed dentition (p=0.0001). Analysis of mean values for mandibular movements in all 3 groups only revealed differences for maximal unassisted opening (p= 0.0317). With relation to gender, TMD was more frequent in females, with significant differences between Groups C and Ia (p=0.019). In males without dysfunction, average maximal opening was 48.28±6.14mm, with lower values in patients with TMD. Mandibular movements in pediatric patients without TMD showed significant differences according to dentition type and age.

  17. 15 years of zooming in and zooming out: Developing a new single scale national active fault database of New Zealand

    NASA Astrophysics Data System (ADS)

    Ries, William; Langridge, Robert; Villamor, Pilar; Litchfield, Nicola; Van Dissen, Russ; Townsend, Dougal; Lee, Julie; Heron, David; Lukovic, Biljana

    2014-05-01

    In New Zealand, we are currently reconciling multiple digital coverages of mapped active faults into a national coverage at a single scale (1:250,000). This seems at first glance to be a relatively simple task. However, methods used to capture data, the scale of capture, and the initial purpose of the fault mapping, has produced datasets that have very different characteristics. The New Zealand digital active fault database (AFDB) was initially developed as a way of managing active fault locations and fault-related features within a computer-based spatial framework. The data contained within the AFDB comes from a wide range of studies, from plate tectonic (1:500,000) to cadastral (1:2,000) scale. The database was designed to allow capture of field observations and remotely sourced data without a loss in data resolution. This approach has worked well as a method for compiling a centralised database for fault information but not for providing a complete national coverage at a single scale. During the last 15 years other complementary projects have used and also contributed data to the AFDB, most notably the QMAP project (a national series of geological maps completed over 19 years that include coverage of active and inactive faults at 1:250,000). AFDB linework and attributes was incorporated into this series but simplification of linework and attributes has occurred to maintain map clarity at 1:250,000 scale. Also, during this period on-going mapping of active faults has improved upon these data. Other projects of note that have used data from the AFDB include the National Seismic Hazard Model of New Zealand and the Global Earthquake Model (GEM). The main goal of the current project has been to provide the best digital spatial representation of a fault trace at 1:250,000 scale and combine this with the most up to date attributes. In some areas this has required a simplification of very fine detailed data and in some cases new mapping to provide a complete coverage

  18. Trends in the Prevalence of Morbid and Severe Obesity in Australian Children Aged 7-15 Years, 1985-2012

    PubMed Central

    Garnett, Sarah P.; Baur, Louise A.; Jones, Aimee M. D.; Hardy, Louise L.

    2016-01-01

    Objective Children with severe obesity have greater risk of adverse health outcomes. The purpose of this study was to assess trends in the prevalence of morbid and severe obesity in Australian children between 1985 and 2012. Methods Secondary analysis of four national Australian cross-sectional surveys of measured height/weight in 7–15 year olds: Australian Health and Fitness Survey 1985 (n = 8,486), National Nutrition Survey 1995 (n = 1,541), the National Children’s Nutrition and Physical Activity Survey 2007 (n = 2,585) and the National Health Survey 2012 (n = 2,940). International Obesity Taskforce cut-point was used for morbid obesity (equivalent to a BMI ≥35kg/m2 at age 18 years). Severe obesity class 2 was defined as BMI ≥120% and <140% of the 95th percentile of the CDC 2000 growth charts or a BMI ≥35 and <40, and severe obesity class 3 as BMI ≥140% of the 95th percentile or a BMI ≥40. Results Between 1985 and 2012 the prevalence of morbid obesity increased from 0.2% to 1.8%, class 2 severe obesity from 0.3% to 2.0%, and class 3 from 0.1% to 0.5%. Children with morbid obesity represented 11.3% of children with obesity in 1985 and increased to 22.5% in 2012 (P = 0.005). Children with severe obesity represented 19.3% of children with obesity in 1985 and increased to 32.0% in 2012 (P = 0.016). The greatest increase was observed between 1995 and 2007. The proportion of children who were classified as morbidly or severely obese was not significantly different between 2007 and 2012, nor was it significantly different between age and sex groups. Conclusion Prevalence of morbid and severe obesity among children is low, but has significantly increased between 1985 and 2012. In contrast to overweight and obese children, children with morbid obesity require tertiary intervention. Failure to treat these children will have significant implications for the individual child and community. PMID:27171503

  19. Assessment of Mandibular Movements in 10 to 15 Year-old Patients With and Without Temporomandibular Disorders.

    PubMed

    Cortese, Silvina G; Biondi, Ana M; Fridman, Diana E; Guitelman, Ingrid; Farah, Catalina L

    2015-12-01

    The aim of this study was to establish reference values for mandibular movements in 10- to 15-year-olds without dysfunction and compare these values to those in patients of the same age with tempromandibular disorders (TMD) and those found previously in a group of children younger than 11 years old without TMD. Children of both genders who visited the Department of Comprehensive Pediatric Dentistry at Buenos Aires University in 2013 and whose parents or guardians provided consent were evaluated using TMD/RDC by standardized pediatric dentists (Kappa 0.88). Three groups were formed according to diagnostic summary: Group C, without TMD; Group Ia, with myofascial pain, and Group Ib, pain with limited mouth opening. The following variables were analyzed: age, gender and mandibular movements. The sample included 169 patients aged 12.5±1.76 years, of whom 62.36% did not have TMD (C) while 37.27% were diagnosed with muscle disorder (29.58% Ia and 7.69% Ib). For Group C, the following values (in mm) were recorded: maximal unassisted opening: 48.28±6.14; right lateral movement 8.78±2.50; left lateral movement: 9.60±2.64; protrusion: 4.94±2.58 and overbite: 2.98 ± 2.5, with no variation associated to sex, but with differences in the values recorded for all movements compared to those obtained for mixed dentition (p=0.0001). Analysis of mean values for mandibular movements in all 3 groups only revealed differences for maximal unassisted opening (p= 0.0317). With relation to gender, TMD was more frequent in females, with significant differences between Groups C and Ia (p=0.019). In males without dysfunction, average maximal opening was 48.28±6.14mm, with lower values in patients with TMD. Mandibular movements in pediatric patients without TMD showed significant differences according to dentition type and age. PMID:27095624

  20. Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species.

    PubMed

    Pistocchi, Rossella; Guerrini, Franca; Pezzolesi, Laura; Riccardi, Manuela; Vanucci, Silvana; Ciminiello, Patrizia; Dell'Aversano, Carmela; Forino, Martino; Fattorusso, Ernesto; Tartaglione, Luciana; Milandri, Anna; Pompei, Marinella; Cangini, Monica; Pigozzi, Silvia; Riccardi, Elena

    2012-01-01

    The Northern Adriatic Sea is the area of the Mediterranean Sea where eutrophication and episodes related to harmful algae have occurred most frequently since the 1970s. In this area, which is highly exploited for mollusk farming, the first occurrence of human intoxication due to shellfish consumption occurred in 1989, nearly 10 years later than other countries in Europe and worldwide that had faced similar problems. Until 1997, Adriatic mollusks had been found to be contaminated mostly by diarrhetic shellfish poisoning toxins (i.e., okadaic acid and dinophysistoxins) that, along with paralytic shellfish poisoning toxins (i.e., saxitoxins), constitute the most common marine biotoxins. Only once, in 1994, a toxic outbreak was related to the occurrence of paralytic shellfish poisoning toxins in the Adriatic coastal waters. Moreover, in the past 15 years, the Adriatic Sea has been characterized by the presence of toxic or potentially toxic algae, not highly widespread outside Europe, such as species producing yessotoxins (i.e., Protoceratium reticulatum, Gonyaulax spinifera and Lingulodinium polyedrum), recurrent blooms of the potentially ichthyotoxic species Fibrocapsa japonica and, recently, by blooms of palytoxin-like producing species of the Ostreopsis genus. This review is aimed at integrating monitoring data on toxin spectra and levels in mussels farmed along the coast of the Emilia-Romagna region with laboratory studies performed on the species involved in the production of those toxins; toxicity studies on toxic or potentially toxic species that have recently appeared in this area are also reviewed. Overall, reviewed data are related to: (i) the yessotoxins producing species P. reticulatum, G. spinifera and L. polyedrum, highlighting genetic and toxic characteristics; (ii) Adriatic strains of Alexandrium minutum, Alexandrium ostenfeldii and Prorocentrum lima whose toxic profiles are compared with those of strains of different geographic origins; (iii) F