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Sample records for 18th ed philadelphia

  1. Observing Sunspots with 18th Century Optics

    NASA Astrophysics Data System (ADS)

    Svalgaard, Leif

    2016-05-01

    The sunspot and group numbers in the 18th Century relies heavily on the observations by J.C. Staudauch during 1749-1799 performed with a three-foot 'sky tube', likely affected by spherical and chromatc aberration. An observing network has been set up to make drawings of the spots on the solar disk using original telescopes from the 18th Century or reconstructed 'sky tubes' with the same defects as the instruments available to and affordable for amateurs of the period. We report the initial results of the effort, finding that the counts of groups and the sunspot numbers must be multipled by three to reproduce modern observations. This confirms the scale factors derived from recent revisions of the solar record.

  2. 18th International Mouse Genome Conference

    SciTech Connect

    Darla R Miller

    2005-07-01

    The 18th International Mouse Genome Conference was held in Seattle, WA, US on October 18-22,2004. The meeting was partially supported by the Department of Energy, Grant No. DE-FG02-04ER63851. Abstracts can be seen at imgs.org and the summary of the meeting was published in “Mammalian Genome”, Vol 16, Number 7, Pages 471-475.

  3. 18th International Conference on Antiviral Research.

    PubMed

    Mitchell, William M

    2005-08-01

    The 18th International Conference on Antiviral Research (ICAR) was held at the Princess Sofia Hotel in Barcelona, Spain, from 11th-14th April, 2005. This is a yearly international meeting sponsored by the International Society for Antiviral Research (ISAR). The current president of ISAR is John A Secrest 3rd of the Southern Research Institute. The scientific programme committee was chaired by John C Drach from the University of Michigan. ISAR was founded in 1987 to exchange prepublication basic, applied and clinical information on the development of antiviral, chemical and biological agents as well as to promote collaborative research. The ISAR has had a major role in the significant advances of the past decade in the reduction of the societal burdens of viral diseases by the focus of ICAR on the discovery and clinical application of antiviral agents. The 18th ICAR was organised as a series of focus presentations on specific viral groups consisting of oral and poster presentations of original research findings. In addition, the conference included plenary speakers, award presentations, a minisymposium on bioterrorism, and a satellite symposium on clinical antiviral drug developments. The size of the conference (> 50 oral and 250 poster presentations) necessitates limitation to the most noteworthy in the judgment of this reviewer. The current membership of the ISAR is approximately 700 with approximately 50% the membership in attendance. PMID:16086663

  4. 8. 1770 S. CANALPORT & 530 W. 18TH STREET. SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. 1770 S. CANALPORT & 530 W. 18TH STREET. SOUTH FRONT MAIN ENTRY OF 1770 CANALPORT & SOUTHEAST CORNER OF 530 W. 18TH STREET. VIEW TO NORTHWEST - Peter Schoenhofen Brewery, West Eighteenth Street & Canalport Avenue, Chicago, Cook County, IL

  5. [Counteraction against alcoholism in religious letters of 18th century].

    PubMed

    Rok, B

    1999-01-01

    The Polish historiography talks at length about the problem of alcoholism in Poland in the 18th century. Estimates were made about the scale and consumption of alcoholic beverages. Many records are available today, mainly in the form of diaries, which describe the extent of drunkenness at that time. Much information on drinking bouts comes from satires (this article quotes after an anonymous satire found in the Polish manuscripts of the 18th century). Apart from the literature, also preachers contributed to the present knowledge of alcohol consumption within that period. Drunkenness was often mentioned in sermons and varied types of religious guides. The 18th century priests deemed drunkenness as a heavy sin and fiercely counteracted the abuse of alcoholic beverages, by condemning people in a state of intoxication. PMID:14631978

  6. [Astrologic and medical manuscript of the 18th Century].

    PubMed

    Kugener, Henri

    2010-01-01

    We present a manuscript from the 18th century, an extract taken from the "Great and the Little Albert" attributed to Albertus Magnus. The linguistic variety in the paper is typical for a text composed in Luxembourg. Added to this text are two incantations and a short cartomancy paper. PMID:20882751

  7. 7. B & O RAILROAD BRIDGE. PHILADELPHIA, PHILADELPHIA CO., PA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. B & O RAILROAD BRIDGE. PHILADELPHIA, PHILADELPHIA CO., PA. Sec. 1101, MP 3.11. - Northeast Railroad Corridor, Amtrak route between Delaware-Pennsylvania & Pennsylvania-New Jersey state lines, Philadelphia, Philadelphia County, PA

  8. 6. B & O RAILROAD BRIDGE. PHILADELPHIA, PHILADELPHIA CO., PA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. B & O RAILROAD BRIDGE. PHILADELPHIA, PHILADELPHIA CO., PA. Sec. 1101, MP 3.11. - Northeast Railroad Corridor, Amtrak route between Delaware-Pennsylvania & Pennsylvania-New Jersey state lines, Philadelphia, Philadelphia County, PA

  9. 20. Zoo Substation. Philadelphia, Philadelphia Co., PA. Sec. 1101, MP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Zoo Substation. Philadelphia, Philadelphia Co., PA. Sec. 1101, MP 87.25. - Northeast Railroad Corridor, Amtrak route between Delaware-Pennsylvania & Pennsylvania-New Jersey state lines, Philadelphia, Philadelphia County, PA

  10. The academician astronomers travelling in the 18th century.

    NASA Astrophysics Data System (ADS)

    Dumont, S.; Débarbat, S.

    1999-04-01

    In the 18th century, astronomers of the Académie des sciences of Paris made various contributions to the improvement of navigation: terrestrial determinations of longitude which improved charts for navigators, testing of marine clocks for longitude determinations at sea. In order to resolve the Cassini-Newton controversy regarding the shape of the Earth, the Académie proposed in 1735, that two expeditions should be made with a view to measuring a meridian arc. The results concluded that the Earth was flat on the sides of the poles, as predicted by Newton. By the mid-18th century, the first purely astronomical expedition (La Caille, Cap of Good Hope) led to the creation of an austral celestial map and new parallaxes. Later, Chappe d'Auteroche, Le Gentil and Pingré travelled to observe two transits of Venus over the Sun (1761, 1769) for the improvement of the solar parallax.

  11. 18th Space Photovoltaic Research and Technology Conference

    NASA Technical Reports Server (NTRS)

    Morton, Thomas L. (Compiler)

    2005-01-01

    The 18th Space Photovoltaic Research and Technology (SPRAT XVIII) Conference was held September 16 to 18, 2003, at the Ohio Aerospace Institute (OAI) in Brook Park, Ohio. The SPRAT conference, hosted by the Photovoltaic and Space Environments Branch of the NASA Glenn Research Center, brought together representatives of the space photovoltaic community from around the world to share the latest advances in space solar cell technology. This year s conference continued to build on many of the trends shown in SPRAT XVII-the continued advances of thin-film and multijunction solar cell technologies and the new issues required to qualify those types of cells for space applications.

  12. Roads and cities of 18th century France.

    PubMed

    Perret, Julien; Gribaudi, Maurizio; Barthelemy, Marc

    2015-01-01

    The evolution of infrastructure networks such as roads and streets are of utmost importance to understand the evolution of urban systems. However, datasets describing these spatial objects are rare and sparse. The database presented here represents the road network at the french national level described in the historical map of Cassini in the 18th century. The digitization of this historical map is based on a collaborative methodology that we describe in detail. This dataset can be used for a variety of interdisciplinary studies, covering multiple spatial resolutions and ranging from history, geography, urban economics to network science. PMID:26401316

  13. Roads and cities of 18th century France

    PubMed Central

    Perret, Julien; Gribaudi, Maurizio; Barthelemy, Marc

    2015-01-01

    The evolution of infrastructure networks such as roads and streets are of utmost importance to understand the evolution of urban systems. However, datasets describing these spatial objects are rare and sparse. The database presented here represents the road network at the french national level described in the historical map of Cassini in the 18th century. The digitization of this historical map is based on a collaborative methodology that we describe in detail. This dataset can be used for a variety of interdisciplinary studies, covering multiple spatial resolutions and ranging from history, geography, urban economics to network science. PMID:26401316

  14. An 18th century Tuscan pharmacy: analysis of the library.

    PubMed

    Giuffra, Valentina

    2015-01-01

    The archival documents of San Luca Hospital, which has long been the most important welfarist institution of the Republic of Lucca (Tuscany), are stored in the Record Offices of Lucca. The hospital was served by a pharmacy, where the medicaments were prepared for patients and for the needs of other institutions in the city. Three different inventories, dating back to 1719, 1749 and 1784, report on a list of books hosted in the pharmacy. The identification and analysis of the works available in the library have allowed to reconstruct the tendencies of pharmacy thoughts and practices in Lucca during the 18th century. The library of the pharmacy of San Luca Hospital revealed the persistence of ancient medicine and of the pharmacy tradition, based mainly on the use of the simples. However, the influence of iatrochemistry, which following the paracelsian theories contributed to convert pharmacy from a botanical science to a chemical discipline, increased in the second half of the century, when the library was enriched with more recent works. The analysis of the inventories demonstrates the presence of both the galenic-arabic and chemical tradition, therefore reflecting an 18th century pharmacy supplied with a composite literature. PMID:26203538

  15. Regina Salomea Pilsztynowa, ophthalmologist in 18th-century Poland.

    PubMed

    Konczacki, Janina M; Aterman, Kurt

    2002-01-01

    Regina Salomea Rusiecki (later Pilsztynowa) was a young, poorly educated Polish Catholic woman in the 18th century who became well known in Eastern Europe and the Ottoman Empire because of her skill in the treatment of cataracts and some other medical problems. She was born in 1718, and at the age of 14 she married an experienced, but significantly older, German Lutheran physician and ophthalmologist, Jakob Halpir. By helping him eagerly in his work, Pilsztynowa learned a great deal of her husband's way of treating cataracts and other ailments, and she ambitiously made use of the friendship and help of other physicians whom she met on her travels. Although there are some occurrences that could lead one to question aspects of Pilsztynowa's straight and honest character, one has also to point to her readiness to help where she could. PMID:11918899

  16. [The interpretation of pulmonary tuberculosis in the 18th century].

    PubMed

    Bernier, Jacques

    2005-01-01

    Pulmonary tuberculosis took on alarming proportions in the 18th-century Europe. This study examines the ways learned medical practitioners presented the causes of the malady in Great Britain and France, by analyzing 12 medical treatises. Four etiological models appears to have dominated medical thinking in this context: theories that emphasize contagion; those which attribute the cause to physiological disorders; those which find the origin in hereditary predispositions; and those theories which observe a link with behaviour and lifestyles. The study also shows how one of these theories - the hereditary theory - eventually triumphed over the others and became the dominant for the better part of the 19th century, and will be examined within the context of the growth of liberal and individualist ideology. PMID:15977379

  17. Scientific Psychology in the 18th Century: A Historical Rediscovery.

    PubMed

    Schwarz, Katharina A; Pfister, Roland

    2016-05-01

    As early as 1783, the almost forgotten philosopher, metaphysicist, and psychologist Ferdinand Ueberwasser (1752-1812) designated himself "Professor für empirische Psychologie und Logik" (professor of empirical psychology and logic) at the University of Münster, Germany. His position was initiated and supported by the minister and educational reformer Franz von Fürstenberg (1729-1810), who considered psychology a core scientific discipline that should be taught at each school and university. At the end of the 18th century, then, psychology seems to have been on the verge of becoming an independent academic discipline, about 100 years before Wilhelm Wundt founded the discipline's first official laboratory. It seems surprising that Ueberwasser's writings-including a seminal textbook on empirical psychology-have been almost entirely overlooked in most historical accounts. We focus on this important founding moment of psychological science and on the circumstances that eventually brought this seminal development to a halt. PMID:27217252

  18. JANNAF 18th Propulsion Systems Hazards Subcommittee Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Cocchiaro, James E. (Editor); Gannaway, Mary T. (Editor)

    1999-01-01

    This volume, the first of two volumes is a compilation of 18 unclassified/unlimited-distribution technical papers presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 18th Propulsion Systems Hazards Subcommittee (PSHS) meeting held jointly with the 36th Combustion Subcommittee (CS) and 24th Airbreathing Propulsion Subcommittee (APS) meetings. The meeting was held 18-21 October 1999 at NASA Kennedy Space Center and The DoubleTree Oceanfront Hotel, Cocoa Beach, Florida. Topics covered at the PSHS meeting include: shaped charge jet and kinetic energy penetrator impact vulnerability of gun propellants; thermal decomposition and cookoff behavior of energetic materials; violent reaction; detonation phenomena of solid energetic materials subjected to shock and impact stimuli; and hazard classification, insensitive munitions, and propulsion systems safety.

  19. Philadelphia and the Tomato.

    ERIC Educational Resources Information Center

    Smith, Andrew F.; Kling, Tatiana

    This booklet describes for elementary students the many contributions of people, traveling many places, over many years to bring the tomato to Philadelphia. The booklet includes the following: (1) "Introduction to the Tomato"; (2) "Where Does the Tomato Come From?"; (3) "The Spanish Tomato"; (4) "The Philadelphia Tomato"; (5) "Growing Tomato…

  20. The Philadelphia Experiment.

    ERIC Educational Resources Information Center

    Mathews, Jay

    2003-01-01

    Describes how the School District of Philadelphia turned over 20 schools to Edison Schools, the for-profit school management firm. Presents the cases of both the opponents and proponents of Edison Schools. Outlines the academic and financial records of the Edison firm and its efforts in Philadelphia. (WFA)

  1. Austrian Pharmacy in the 18th and 19th Century

    PubMed Central

    Kletter, Christa

    2010-01-01

    This overview reflects the extensive changes in the health care system which had significant effects on the apothecary’s profession and education. In the 18th century Maria Theresia assigned Gerard van Swieten to modernize the medical curriculum and to work out reforms for health care. The resulting sanitary bill released in 1770 and amended in 1773 became effective for the whole empire and influenced greatly the apothecary’s profession. The Viennese Medical Faculty continued to be the supervisory body for the apothecaries, a situation which prolonged the conflicts between the faculty and the apothecaries. The financial and social distress prevalent in the 19th century also affected the apothecary business and led to a crisis of the profession. Furthermore, the apothecaries’ missing influence over the sanitary authorities delayed the release of a badly needed new apothecary bill until 1906. The introduction of a specific pharmaceutical curriculum at the university in 1853 was a great step forward to improve the pharmaceutical education. Nevertheless, the secondary school exam was not compulsory for the studies until 1920 and, therefore, the graduates were not on a par with other university graduates before that date. Women, except nuns, were not allowed to work as pharmacists until 1900. PMID:21179353

  2. FOREWORD: 18th International School on Condensed Matter Physics

    NASA Astrophysics Data System (ADS)

    Dimova-Malinovska, Doriana; Genova, Julia; Nesheva, Diana; Petrov, Alexander G.; Primatarowa, Marina T.

    2014-12-01

    We are delighted to present the Proceedings of the 18th International School on Condensed Matter Physics: Challenges of Nanoscale Science: Theory, Materials, Applications, organized by the Institute of Solid State Physics of the Bulgarian Academy of Sciences and chaired by Professor Alexander G Petrov. On this occasion the School was held in memory of Professor Nikolay Kirov (1943-2013), former Director of the Institute and Chairman between 1991 and 1998. The 18ISCMP was one of several events dedicated to the 145th anniversary of the Bulgarian Academy of Sciences in 2014, and was held in the welcoming Black Sea resort of St. Constantine and Helena near Varna, at the Hotel and Congress Centre Frederic Joliot-Curie. Participants from 16 countries delivered 32 invited lectures, and 71 contributed posters were presented over three lively and well-attended evening sessions. Manuscripts submitted to the Proceedings were refereed in accordance with the guidelines of the Journal of Physics: Conference Series, and we believe the papers published herein testify to the high technical quality and diversity of contributions. A satellite meeting, Transition Metal Oxide Thin Films - Functional Layers in Smart Windows and Water Splitting Devices: Technology and Optoelectronic Properties was held in parallel with the School (http://www.inera.org, 3-6 Sept 2014). This activity, which took place under the FP7-funded project INERA, offered opportunities for crossdisciplinary discussions and exchange of ideas between both sets of participants. As always, a major factor in the success of the 18ISCMP was the social programme, headed by the organized events (Welcome and Farewell Parties) and enhanced in no small measure by a variety of pleasant local restaurants, bars and beaches. We are most grateful to staff of the Journal of Physics: Conference Series for their continued support for the School, this being the third occasion on which the Proceedings have been published under its

  3. Mingantu, 18th-Century Mongol Astronomer and Radioheliograph Namesake

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.

    2013-01-01

    The 18th-century Mongol astronomer Mingantu (1692-1765) has been honored with a city named after him and a nearby solar telescope array. During the IAU/Beijing, my wife and I went to the new Chinese solar radioheliograph, the Mingantu Observing Station, in Inner Mongolia, ~400 km northwest of Beijing, a project of the National Astronomical Observatories, Chinese Academy of Sciences. It currently contains 40 dishes each 4.5 m across, with a correlator from Beijing. Within a year, 60 2-m dishes will be added. We passed by the 12-century ruins of Xanadu (about 20 km north of Zhangbei) about halfway. The radioheliograph is in a plane about 1 km across, forming a three-armed spiral for interferometric solar mapping, something colleagues and I had carried out with the Jansky Very Large Array, taking advantage of the lunar occultation before annularity at the 20 May 2012 solar eclipse. In the central square of Mingantu city, a statue ~10-m high of the Mongol astronomer Mingantu appears. Its base bears a plaque ~1-m high of IAU Minor Planet Circular MPC 45750 announcing the naming in 2002 of asteroid 28242 Mingantu, discovered at a Chinese observatory in 1999. Mingantu carried out orbital calculations, mapping, mathematical work on infinite series, and other scientific research. He is honored by a modern museum behind the statue. The museum's first 40% describes Mingantu and his work, and is followed by some artifacts of the region from thousands of years ago. The final, large room contains a two-meter-square scale model of the radioheliograph, flat-screen televisions running Solar Dynamics Observatory and other contemporary visualizations, orreries and other objects, and large transparencies of NASA and other astronomical imagery. See my post at http://www.skyandtelescope.com/community/skyblog/newsblog/ specfically Astro-Sightseeing_in_Inner_Mongolia-167712965.html. We thank Yihua Yan for arranging the visit and Wang Wei (both NAOC) for accompanying us. My solar research

  4. Preface: 18th Aps-Sccm and 24th Airapt

    NASA Astrophysics Data System (ADS)

    Collins, Gilbert; Moore, David S.; Yoo, Choong-Shik; Buttler, William; Furlanetto, Michael; Evans, William

    2014-05-01

    The 18th Biennial International Conference of the APS Topical Group on Shock Compression of Condensed Matter in conjunction with the 24th Biennial International Conference of the International Association for the Advancement of High Pressure Science & Technology (AIRAPT) was held at the Westin Hotel in Seattle, Washington from 7-12 July, 2013. This is only the second time that these two organizations have held a Joint Conference — the first was 20 years previous (1993) in Colorado Springs, Colorado. Seattle was chosen for this joint conference because of its central location for the world-wide attendees as well as its metropolitan vibrancy. The scientific program consisted of 858 scheduled presentations organized into 23 topical areas and included contributed (537), invited (95), and plenary (6) lectures, as well as two poster sessions with 110 posters each. The scientific focus of the Joint Conference was on fundamental and applied research topics related to the static or dynamic compression of condensed matter. This multidisciplinary field of research encompasses areas of physics, chemistry, materials science, mechanics, geophysics and planetary physics, and applied mathematics. Experimental, computational and theoretical studies all play important roles. The organizers endeavored to intertwine static and dynamic experimental alongside computational and theoretical studies of similar materials in the organization of the sessions. This goal was aided by the addition of three special focus sessions on deep carbon budget, high energy density materials, and dynamic response of materials. 722 scientists and engineers from 25 countries registered at the conference, including 132 students from 12 countries. The attendee countries represented included: Argentina (2), Australia (2), Brazil (3), Canada (25), China (22), Czech Republic (2), France (35), Germany (19), India (6), Israel (21), Italy (10), Japan (49), Netherlands (1), Poland (1), Portugal (2), Russia (26

  5. PREFACE: 18th Microscopy of Semiconducting Materials Conference (MSM XVIII)

    NASA Astrophysics Data System (ADS)

    Walther, T.; Hutchison, John L.

    2013-11-01

    YRM logo This volume contains invited and contributed papers from the 18th international conference on 'Microscopy of Semiconducting Materials' held at St Catherine's College, University of Oxford, on 7-11 April 2013. The meeting was organised under the auspices of the Royal Microscopical Society and supported by the Institute of Physics as well as the Materials Research Society of the USA. This conference series deals with recent advances in semiconductor studies carried out by all forms of microscopy, with an emphasis on electron microscopy and scanning probe microscopy with high spatial resolution. This time the meeting was attended by 109 delegates from 17 countries world-wide. We were welcomed by Professor Sir Peter Hirsch, who noted that this was the first of these conferences where Professor Tony Cullis was unable to attend, owing to ill-health. During the meeting a card containing greetings from many of Tony's friends and colleagues was signed, and duly sent to Tony afterwards. As semiconductor devices shrink further new routes for device processing and characterisation need to be developed, and, for the latter, methods that offer sub-nanometre spatial resolution are particularly valuable. The various forms of imaging, diffraction and spectroscopy available in modern microscopes are powerful tools for studying the microstructure, electronic structure, chemistry and also electric fields in semiconducting materials. Recent advances in instrumentation, from lens aberration correction in both TEM and STEM instruments, to the development of a wide range of scanning probe techniques, as well as new methods of signal quantification have been presented at this conference. Two topics that have at this meeting again highlighted the interesting contributions of aberration corrected transmission electron microscopy were: contrast quantification of annular dark-field STEM images in terms of chemical composition (Z-contrast), sample thickness and strain, and the study of

  6. Undergraduate Program: Philadelphia

    NASA Astrophysics Data System (ADS)

    Betsock, Lori

    2008-08-01

    Undergraduate chemical science students—join us in Philadelphia on August 17 and 18, 2008, for an educational and career-oriented program designed specifically for you. Attend symposia about global climate change and clean energy; hear Nobel Laureate F. Sherwood Rowland speak about his fascinating career, "A Life in Tracer Chemistry". Weigh options for your future by attending the Graduate School Reality Check and graduate school recruiting events. All events will take place in the Sheraton Philadelphia City Center at 17th and Race Streets, except the Undergraduate Poster Sessions and Sci-Mix, which will be held in the Pennsylvania Convention Center.

  7. EDITORIAL: 18th European Conference on Dynamics of Molecular Systems 18th European Conference on Dynamics of Molecular Systems

    NASA Astrophysics Data System (ADS)

    Varandas, A. J. C.

    2011-08-01

    This special section of Comments on Atomic, Molecular and Optical Physics (CAMOP) in Physica Scripta collects some of the papers that have been presented at the 18th European Conference on Dynamics of Molecular Systems MOLEC 2010 held in September 2010 in Curia, Portugal, as part of a series of biennial MOLEC conferences. This started in 1976 in Trento, Italy, and has continued, visiting 17 cities in 11 countries, namely Denmark, The Netherlands, Israel, France, Italy, Germany, Czech Republic, Spain, United Kingdom, Turkey and Russia. Following the MOLEC tradition, the scientific programme of the Curia meeting focused on experimental and theoretical studies of molecular interactions, collision dynamics, spectroscopy, and related fields. It included invited speakers from 22 countries, who were asked to summarize the problems reported in their presentations with the objective of revealing the current thinking of leading researchers in atomic, molecular and optical physics. It is hoped that their authoritative contributions presented in this CAMOP special section will also appeal to non-specialists through their clear and broad introductions to the field as well as references to the accessible literature. This CAMOP special section comprises ten contributions, which cover theoretical studies on the electronic structure of molecules and clusters as well as dynamics of elastic, inelastic and reactive encounters between atoms, molecules, ions, clusters and surfaces. Specifically, it includes electronic structure calculations using the traditional coupled-cluster method (Barreto et al 028111), the electron-attached equation-of-motion coupled cluster method (Hansen et al 028110), the diffusion Monte Carlo method (López-Durán et al 028107) and the path-integral Monte Carlo method (Barragán et al 028109). The contributions on molecular dynamics include on-the-fly quasi-classical trajectories on a five-atom molecule (Yu 028104), quantum reaction dynamics on triatomics

  8. School Closings in Philadelphia

    ERIC Educational Resources Information Center

    Jack, James; Sludden, John

    2013-01-01

    In 2012, the School District of Philadelphia closed six schools. In 2013, it closed 24. The closure of 30 schools has occurred amid a financial crisis, headlined by the district's $1.35 billion deficit. School closures are one piece of the district's plan to cut expenditures and close its budget gap. The closures are also intended to…

  9. PHILADELPHIA ROADWAY STUDY

    EPA Science Inventory

    The Philadelphia Roadway Study was conducted to determine the horizontal and vertical extinction profiles of particles generated by vehicles, including fine (0-2.5 micrometers), coarse (2.5-15 micrometers), and total (0-15 micrometers) size fractions in the area surrounding a maj...

  10. EDITORIAL: The 18th Central European Workshop on Quantum Optics The 18th Central European Workshop on Quantum Optics

    NASA Astrophysics Data System (ADS)

    Sánchez-Soto, Luis L.; Man'ko, Margarita A.

    2012-02-01

    to the proceedings of the 15th CEWQO (Physica Scripta 2009 T135 011005). The 18th edition of CEWQO (CEWQO11) was held in Madrid in 2011. There were about 250 participants, from practically every European country. Many colleagues from other continents also joined the event, including well-established researchers in the field. This is a clear demonstration that these meetings provide an excellent chance to hear about the latest results and new directions of research. The organization of CEWQO11 was carried out by a committee consisting of members active in this topic in Madrid. From Universidad Complutense, Alberto Galindo and Luis L Sánchez-Soto from Universidad Autónoma, Jose Calleja and Carlos Tejedor; from Universidad Politécnica, Enrique Calleja; from Universidad Carlos III, Alberto Ibort; and from the National Research Council (CSIC), Juan León and Juan J García-Ripoll. Special thanks go to the Spanish Ministry for Science and Innovation, Universidad Complutense and the Quitemad Consortium for financial support. The proceedings of the 16th CEWQO held at the University of Turku, Finland and the 17th CEWQO held at the University of St Andrews, Scotland, UK are also available (Physica Scripta 2010 T140 and Physica Scripta 2011 T143). The present Topical Issue is a collection of papers presented in Madrid; they represent an illustrative sample of the major achievements and trends in this area. In turn, they reflect the wide range of interests in this rapidly evolving field. Some collaborators from different scientific centres who could not, due to different reasons, come to Madrid, but participated in previous CEWQOs and plan to participate in future CEWQOs, also contributed to this issue. The papers are arranged alphabetically by the name of the first author. Special thanks goes to Roger Wäppling, the Managing Editor of Physica Scripta, and Graeme Watt, the Publisher, for the opportunity to publish CEWQO11. From a Physica Scripta Editorial Board meeting it was

  11. PERSPECTIVE VIEW OF EAST (FRONT) ELEVATION DURING EXCAVATION OF 18TH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PERSPECTIVE VIEW OF EAST (FRONT) ELEVATION DURING EXCAVATION OF 18TH CENTURY BASEMENT ENTRY WELL AND DRAINAGE SYSTEM, LOOKING NORTHWEST - Belair, Tulip Grove Drive, Belair-at-Bowie, Bowie, Prince George's County, MD

  12. 8. Pennsylvania Railroad: 30th Street Station Powerhouse. Philadelphia, Philadelphia Co., ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Pennsylvania Railroad: 30th Street Station Powerhouse. Philadelphia, Philadelphia Co., PA. Sec. 1101, MP 88.11. - Northeast Railroad Corridor, Amtrak route between Delaware-Pennsylvania & Pennsylvania-New Jersey state lines, Philadelphia, Philadelphia County, PA

  13. 11. Pennsylvania Railroad: 30th Street Station. Philadelphia, Philadelphia Co., PA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Pennsylvania Railroad: 30th Street Station. Philadelphia, Philadelphia Co., PA. Sec. 1101, MP 88.10. - Northeast Railroad Corridor, Amtrak route between Delaware-Pennsylvania & Pennsylvania-New Jersey state lines, Philadelphia, Philadelphia County, PA

  14. 10. Pennsylvania Railroad: 30th Street Station. Philadelphia, Philadelphia Co., PA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Pennsylvania Railroad: 30th Street Station. Philadelphia, Philadelphia Co., PA. Sec. 1101, MP 88.10. - Northeast Railroad Corridor, Amtrak route between Delaware-Pennsylvania & Pennsylvania-New Jersey state lines, Philadelphia, Philadelphia County, PA

  15. 9. Pennsylvania Railroad: 30th Street Station. Philadelphia, Philadelphia Co., PA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Pennsylvania Railroad: 30th Street Station. Philadelphia, Philadelphia Co., PA. Sec. 1101, MP 88.10. - Northeast Railroad Corridor, Amtrak route between Delaware-Pennsylvania & Pennsylvania-New Jersey state lines, Philadelphia, Philadelphia County, PA

  16. Negative Numbers in the 18th and 19th Centuries: Phenomenology and Representations

    ERIC Educational Resources Information Center

    Maz-Machado, Alexander; Rico-Romero, Luis

    2009-01-01

    This article presents a categorization of the phenomena and representations used to introduce negative numbers in mathematics books published in Spain during the 18th and 19th centuries. Through a content analysis of fourteen texts which were selected for the study, we distinguished four phenomena typologies: physical, accounting, temporal and…

  17. Samson Occom: Mohegan Missionary and Writer of the 18th Century.

    ERIC Educational Resources Information Center

    Peyer, Bernd

    1982-01-01

    One of the first Native American authors, Samson Occom, a Mohegan Indian, began writing in the 18th century. His writings included an ethnographic essay on the Montauk Tribe, an autobiographical sketch of his educational experiences and missionary activities, and his first publication, "Sermon at the Execution of Moses Paul." (ERB)

  18. Johann Heinrich Pestalozzi: 18th Century Swiss Educator and Correctional Reformer

    ERIC Educational Resources Information Center

    Bowers, Fredalene B.; Gehring, Thom

    2004-01-01

    This is the second in a series of articles on famous correctional educators. The first article introduced Mary Carpenter: 19th Century English Correctional Education Hero. (Editor's Note: See the September 2003 Issue for the first article) This article focuses on Johann Heinrich Pestalozzi, 18th century Swiss educator. It begins with a summary of…

  19. John Stirling and the Classical Approach to Style in 18th Century England.

    ERIC Educational Resources Information Center

    Moran, Michael G.

    Most 18th-century rhetoricians viewed style as the expression of a writer's individual character and thought, placing little emphasis on the lists of figures common in many 17th-century rhetorics. John Stirling and others, however, continued the 17th-century tradition that reduced rhetoric largely to style and emphasized classical figures of…

  20. 6. LOOKING WEST SOUTHWEST, 18th STREET BRIDGE AT RIGHT, PENNSYLVANIA ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. LOOKING WEST SOUTHWEST, 18th STREET BRIDGE AT RIGHT, PENNSYLVANIA RAILROAD BRIDGE IN MIDDLE, CHICAGO TRANSIT AUTHORITY ORANGE LINE AT LEFT. - Pennsylvania Railroad, South Branch Chicago River Bridge, Spanning South Branch of Chicago River Bridge east of Canal Street, Chicago, Cook County, IL

  1. Pacific Telecommunications Council Annual Conference Proceedings (18th, Honolulu, Hawaii, January 14-18, 1996).

    ERIC Educational Resources Information Center

    Wedemeyer, Dan J. Ed.; Nickelson, Richard, Ed.

    The Pacific Telecommunications Council's 18th annual conference is presented in two volumes. The PTC'96 gathering focused on seven streams: socio-economic issues; regulatory, legal and political issues; business and finance solutions; country studies; education, training, and human resources; convergence and networks; and technologies and…

  2. The Treatment of the Motion of a Simple Pendulum in Some Early 18th Century Newtonian Textbooks

    ERIC Educational Resources Information Center

    Gauld, Colin

    2004-01-01

    The treatment of pendulum motion in early 18th century Newtonian textbooks is quite different to what we find in today's physics textbooks and is based on presuppositions and mathematical techniques which are not widely used today. In spite of a desire to present Newton's new philosophy of nature as found in his "Principia" 18th century textbook…

  3. Solutions To the Problem of Impact in the 17th and 18th Centuries and Teaching Newton's Third Law Today.

    ERIC Educational Resources Information Center

    Gauld, Colin

    1998-01-01

    Compares the ideas of young people about Newton's third law, focusing on youth of today and youth of the 17th and 18th centuries. Examines the use of Newton's third law in understanding impact phenomena in the 17th and 18th centuries. Contains 46 references. (DDR)

  4. 76 FR 25710 - Comment Request for Information Collection for Employment and Training (ET) Handbook 336, 18th...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ..., based on BAM survey results. The SQSP Handbook No. 336 includes an action plan for each state to... Request for Information Collection for Employment and Training (ET) Handbook 336, 18th Edition... concerning the collection of data about the proposed extension to ET Handbook 336, 18th...

  5. [Masters of obstetrics in the area of Vojvodina in the 18th and 19th century].

    PubMed

    Berić, B M

    1994-01-01

    The author reviews data about masters of obstetrics, physicians and surgeons nonphysicians, who worked in Vojvodina from the second half of the 18th till the beginning of the 20th century. They used to be the professional and time bridge as well as extremely important developmental link of continuity between the obstetrics of untrained and subsequently educated midwives and physicians gyneco--surgeons, later specialists gynecologists--obstetricians all as a part of integral discipline of gynecology and obstetrics in the area of Vojvodina. The existence of about 30 masters of obstetrics in the area of today's Vojvodina from the 18th to the 20th century, educated at medical faculties of Vienna, Budapest and Graz, points to the fact that obstetrics and gynecology in our regions in the 18th and especially 19th and 20th centuries, used to have similar, and somewhere identical trends and directions of development, like the obstetrics and gynecology of Central Europe of that time and that it used to be, just like it is today, a part of European gynecology and obstetrics. PMID:7739446

  6. 6. ANOTHER GRANDSTAND ENTRANCE, EAST WING OF GRANDSTAND. NOTE PHILADELPHIA ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. ANOTHER GRANDSTAND ENTRANCE, EAST WING OF GRANDSTAND. NOTE PHILADELPHIA ATHLETICS'S LETTER 'A' ON CARTOUCHE. - Shibe Park (Stadium), 2701 North Twenty-first Street, Philadelphia, Philadelphia County, PA

  7. Overview from west bank of Schuykill River. Philadelphia & ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Overview from west bank of Schuykill River. - Philadelphia & Reading Railroad, Bridge at West Falls, Spanning Schuylkill River, southeast of Roosevelt Boulevard Bridge, Philadelphia, Philadelphia County, PA

  8. 17. DETAIL OF BUILDER'S PLAQUE, LOOKING NORTH. Philadelphia & ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. DETAIL OF BUILDER'S PLAQUE, LOOKING NORTH. - Philadelphia & Reading Railroad, Wissahickon Creek Viaduct, Spanning Wissahickon Creek, north of Ridge Avenue Bridge, Philadelphia, Philadelphia County, PA

  9. 28. TURBINE HALL, ORIGINAL TURBO GENERATOR, LOOKING EAST Philadelphia ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. TURBINE HALL, ORIGINAL TURBO GENERATOR, LOOKING EAST - Philadelphia Electric Company, Richmond Power Station, Southeast end of Lewis Street along Delaware River, Philadelphia, Philadelphia County, PA

  10. 36. TURBINE HALL, NEW TURBO GENERATOR, LOOKING NORTHEAST Philadelphia ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. TURBINE HALL, NEW TURBO GENERATOR, LOOKING NORTHEAST - Philadelphia Electric Company, Richmond Power Station, Southeast end of Lewis Street along Delaware River, Philadelphia, Philadelphia County, PA

  11. 33. TURBINE HALL, ORIGINAL TURBO GENERATOR, INTACT CONDENSER Philadelphia ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. TURBINE HALL, ORIGINAL TURBO GENERATOR, INTACT CONDENSER - Philadelphia Electric Company, Richmond Power Station, Southeast end of Lewis Street along Delaware River, Philadelphia, Philadelphia County, PA

  12. 35. TURBINE HALL, NEW TURBO GENERATOR, LOOKING SOUTHEAST Philadelphia ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. TURBINE HALL, NEW TURBO GENERATOR, LOOKING SOUTHEAST - Philadelphia Electric Company, Richmond Power Station, Southeast end of Lewis Street along Delaware River, Philadelphia, Philadelphia County, PA

  13. 13. WEST END, LOOKING NE, PHILADELPHIA ZOO LION SCULPTURE IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. WEST END, LOOKING NE, PHILADELPHIA ZOO LION SCULPTURE IN FOREGROUND. - Connecting Railway, Schuylkill River Bridge, Spanning Schuylkill River, north of Girard Avenue Bridge, Philadelphia, Philadelphia County, PA

  14. 1. Photocopy of photograph (collection of Dillon and Co., Philadelphia) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of photograph (collection of Dillon and Co., Philadelphia) Photographer unknown, 1893 NORTHEAST FRONT AND SOUTHEAST SIDE - Philadelphia & Reading Railroad, Terminal Station, 1115-1141 Market Street, Philadelphia, Philadelphia County, PA

  15. 2. Photocopy of the fountain in front of Philadelphia Museum ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of the fountain in front of Philadelphia Museum of Art, ca. 1928, courtesy of Philadelphia Museum of Art - Fountain of the Sea Horses, Aquarium Lane, Philadelphia, Philadelphia County, PA

  16. Zach, Gotha and the Venus transits of the 18th and 19th centuries

    NASA Astrophysics Data System (ADS)

    Duerbeck, Hilmar W.

    Zach was a child and a secondary school boy when the Venus transits of the 18th century occurred, and we try to elucidate the somewhat garbled note given in Lalande' Bibliographie (1803). Zach - like many others - was interested in seeing a definitive result emerge from the observations. Encke, one of the first serious analysts of the observations, was supplied with information by Zach. We will briefly describe the attempts of Euler, du Séjour, Encke, Powalky and Newcomb to determine a reliable value of the solar parallax (the last one being finished only after the next pair of Venus transits had occurred!), and outline Zach's role in this field.

  17. Building 21: B21 Philadelphia

    ERIC Educational Resources Information Center

    EDUCAUSE, 2015

    2015-01-01

    As a non-selective neighborhood high school in the School District of Philadelphia, B21's mission is to empower networks of learners to connect with their passions and build agency to impact their world. Building 21 is organized into studios, workshops, and advisories. Core studios engage students in project-based learning. Blended learning…

  18. Philadelphia's "Servant-Leader" Superintendent

    ERIC Educational Resources Information Center

    Puente, Kelly

    2012-01-01

    This article profiles William Hite, Jr., a longtime educator and administrator, who began his career more than two decades ago as a high school athletic coach. Hite says his biggest passion is educating young people. And one of the best ways to serve students, he says, is by listening. Hite, 51, assumed his duties as Philadelphia's new…

  19. Getting REAL: The Philadelphia Story

    ERIC Educational Resources Information Center

    Lackney, Jefferey A.

    2006-01-01

    This article consists of the second part of an interview with John Sole and David Schrader on the Redesign of the High Schools in Philadelphia: Integrating Project Project-Based Learning and the Architectural Process January 2006. The first segment examined the work of educator John Sole. He emphasizes an active, self-directed project-based,…

  20. Cultural Participation in the Philadelphia Area.

    ERIC Educational Resources Information Center

    Hanford, Terry; And Others

    Described are the results of two separate surveys of cross-sections of the Philadelphia public concerning their cultural behavior, attitudes, and perceptions. The more recent survey was conducted in 1984 with a random telephone sample of 404 Philadelphia residents. The other survey consisted of a subset of approximately 400 Philadelphia area…

  1. Chapter 9: understanding the nervous system in the 18th century.

    PubMed

    Smith, Christopher U M

    2010-01-01

    The 18th century was an age of transition. The time-honored neuropsychology of classical and medieval times, mechanized in Descartes' hydraulic neurophysiology, was undermined by microscopical observations and careful physiological experimentation. Yet it was not until the very end of the century, when work on electric fish and amphibia began to suggest an acceptable successor to "animal spirit," that the old understanding of human neurophysiology began to fade. This chapter traces this slow retreat from the iatrophysics of the early part of the century, with its hollow nerves and animal spirits, through a number of stop-gap explanations involving mysterious subtle fluids or forces described variously as irritability, élan vital, vis viva, vis insita, the spirit of animation etc., or perhaps involving vibrations and vibratiuncles and mysterious magnetic effluvia, to the dawning electrophysiology of the end of the century and the beginning of the next. This developing understanding filtered slowly through to affect medical education, and the 18th century saw the development of strong medical schools at Leiden, Edinburgh, Paris, Bologna and London. Associated with these developments there was a great increase, as a well-known physician looking back at the beginning of the following century noted, in a class of diseases that had little concerned physicians in the preceding century - "nervous disorders." PMID:19892112

  2. Occupational medicine in the Idria mercury mine in the 18th century.

    PubMed

    Slavec, Z Z

    1998-12-01

    Of all medical sciences in Slovenia, occupational medicine has the longest tradition. It is not a mere coincidence that it had developed already at the beginning of 18th century in Idria. The Mercury mine in Idria, is the second largest European mine of its kind, next to the Spanish Almaden, and has been owned by the Habsburg dynasty for four centuries. To attain higher production, the miners in Idria received medical and social care much earlier than anywhere else; chronic intoxication caused by mercury fumes greatly hindered their working ability. The first and, at the same time, one of the most prominent doctors in Idria, J.A. Scopoli (1723-1788) perfectly described the symptoms of chronic intoxication with mercury in his work De Hydrargyro Idriensi Tentamina Physico-Chymico-Medica (Venice, 1761) and thus ranked himself among the early medical writers of occupational medicine, medical hygiene and toxicology. His predecessors were Ellenbog, Paracelsus, Mattioli and some others. The article describes the situation in the mine of Idria in the 17th and 18th century and focusses on Scopoli's mineralogical and medical discussion on mercury miners and mercurialism. PMID:11623564

  3. From Flamsteed to Piazzi and Lalande: new standards in 18th century astrometry

    NASA Astrophysics Data System (ADS)

    Lequeux, James

    2014-07-01

    Aims: The present high accuracy of stellar positions and proper motions allows us to determine the positional accuracy of old stellar catalogues. This has already been done for the most important catalogues from before the 18th century. Our aim is to extend this study to several 18th century catalogues. Methods: To do this, I studied ten catalogues: those of Flamsteed and Rømer, four catalogues of La Caille, and catalogues of Tobias Mayer, Bradley, Piazzi, and Lalande. A comparison with modern data, mostly from Hipparcos, compiled in the Simbad database of the CDS allowed me to determine the position errors of these catalogues. I also compared the stellar visual magnitudes given in eight of these catalogues with photometric V magnitudes. Results: Thanks to novel instruments, the rms positional accuracy improved from thousands to hundreds of arcsec in older catalogues to less than one minute in that of Flamsteed, and to 2-6 arcsec in the other catalogues I examined. These improvements allowed for the first time relatively accurate proper motions to be determined by 19th century astronomers. The catalogues with some corrections are available in digital form at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/567/A26

  4. Burns

    MedlinePlus

    ... of Surgery . 18th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap 22. Holmes JH, Heimbach DM. Burns. In: Brunicardi FC, Andersen DK, Billiar TR, et al, eds. Schwartz's Principles of Surgery . 9th ed. New ...

  5. Analyses of Etna Eruptive Activity From 18th Century and Characterization of Flank Eruptions

    NASA Astrophysics Data System (ADS)

    del Carlo, P.; Branca, S.; Coltelli, M.

    2003-12-01

    Etna explosive activity has usually been considered subordinate with respect to the effusive eruptions. Nevertheless, in the last decade and overall after the 2001 and 2002 flank eruptions, explosive activity has drawn the attention of the scientific and politic communities owing to the damages that the long-lasting ash fall caused to Sicily's economy. We analyzed the eruptions from the 18th century to find some analogous behavior of Etna in the past. A study of the Etna historical record (Branca and Del Carlo, 2003) evidenced that after the 1727 eruption, there are no more errors in the attribution of the year of the eruption. Furthermore from this time on, the scientific quality of the chronicles allowed us to obtain volcanological information and to estimate the magnitude of the major explosive events. The main goal of this work was to characterize the different typologies of Etna eruptions in the last three centuries. Meanwhile, we have tried to find the possible relationship between the two kinds of activity (explosive and effusive) in order to understand the complexity of the eruptive phenomena and define the short-term behavior of Etna. On the base of the predominance of the eruptive typology (effusive or explosive) we have classified the flank eruptions in three classes: i) Type 1: almost purely effusive; ii) Type 2: the intensity of explosive activity comparable with the effusive; iii) Type 3: almost purely explosive with minor lava effusion (only the 1763 La Montagnola and 2002 eruptions belong to this class). Long-lasting explosive activity is produced by flank eruptions with continuous ash emission and prolonged fallout on the flanks (e.g. 1763, 1811, 1852-53, 1886, 1892, 2001 and 2002 eruptions). At summit craters continuous activity is weaker, whereas the strongest explosive eruptions are short-lived events. Furthermore, from the 18th to 20th century there were several years of intense and discontinuous summit explosive activity, from high strombolian

  6. Auroras Observed in Portugal in Late 18th Century Obtained from Printed and Manuscript Meteorological Observations

    NASA Astrophysics Data System (ADS)

    Vaquero, José M.; Trigo, Ricardo M.

    2005-09-01

    We present a new catalogue of observations of the aurora borealis at Lisbon, i.e., at low-latitudes, in the late 18th century by Jacob Præ torius and Henrique Schulze, two German artillery officers. Dates of 18 auroras compiled by Præ torius and Schulze are compared with those published in other catalogues for that period. The number of annual auroras observed by the two Germans is then compared with two indices of solar activity showing a very good level of consistency between all time series. Finally, we have assessed the number of auroras observed taking into consideration the phase of the lunar cycle and the geomagnetic latitude of Lisbon.

  7. An analytical Raman spectroscopic study of an important english oil painting of the 18th Century

    NASA Astrophysics Data System (ADS)

    Edwards, Howell G. M.; Vandenabeele, Peter; Jehlicka, Jan; Benoy, Timothy J.

    2014-01-01

    An opportunity was afforded to analyse pigment specimens from an unrestored oil painting in the style of the English School of the mid-18th Century prior to conservation being undertaken. Raman spectroscopy was adopted to characterise the pigments and indicated the presence of a novel red pigment which was assigned to the complex chromium mineral, hemihedrite, in addition to other interesting materials found in combination. This is the first recorded identification of hemihedrite spectral signals in an art context in a range of mineral pigments that are otherwise typical of this period and some hypotheses are presented to explain its presence based on its occurrence with associated mineral pigments. It is suggested that the presence of powdered glass identified in certain areas of the painting enhanced the reflectivity of the pigment matrix.

  8. The 18th Congress of the International Society for Aerosols in Medicine.

    PubMed

    Mitchell, Jolyon P; Nichols, Steven C

    2011-09-01

    The 18th biennial Congress of ISAM was held for 4 days at the De Doelen Congress Centre, Rotterdam, Netherlands, at which approximately 350 delegates, including 60 session chairs and speakers, attended. The abstracts of the 49 podium talks and the 126 posters that were presented have been published in the society's technical journal (journal of Aerosol Medicine and Pulmonary Delivery), and the detailed program can be found on the ISAM website (www.isam.org). Postgraduate courses on the topics: 'Inhalation Therapy at the Intensive Care Unit'; 'Walking the Standards Maze: Standards for Device Development, Device Performance and Regulatory Approval'; and 'Nuts and Bolts of Aerosol Delivery: Theory, Guidelines and Practice', were offered to participants prior to the Congress itself. PMID:22833908

  9. Isotopic Ag-Cu-Pb record of silver circulation through 16th-18th century Spain.

    PubMed

    Desaulty, Anne-Marie; Telouk, Philippe; Albalat, Emmanuelle; Albarède, Francis

    2011-05-31

    Estimating global fluxes of precious metals is key to understanding early monetary systems. This work adds silver (Ag) to the metals (Pb and Cu) used so far to trace the provenance of coinage through variations in isotopic abundances. Silver, copper, and lead isotopes were measured in 91 coins from the East Mediterranean Antiquity and Roman world, medieval western Europe, 16th-18th century Spain, Mexico, and the Andes and show a great potential for provenance studies. Pre-1492 European silver can be distinguished from Mexican and Andean metal. European silver dominated Spanish coinage until Philip III, but had, 80 y later after the reign of Philip V, been flushed from the monetary mass and replaced by Mexican silver. PMID:21606351

  10. Isotopic Ag–Cu–Pb record of silver circulation through 16th–18th century Spain

    PubMed Central

    Desaulty, Anne-Marie; Telouk, Philippe; Albalat, Emmanuelle; Albarède, Francis

    2011-01-01

    Estimating global fluxes of precious metals is key to understanding early monetary systems. This work adds silver (Ag) to the metals (Pb and Cu) used so far to trace the provenance of coinage through variations in isotopic abundances. Silver, copper, and lead isotopes were measured in 91 coins from the East Mediterranean Antiquity and Roman world, medieval western Europe, 16th–18th century Spain, Mexico, and the Andes and show a great potential for provenance studies. Pre-1492 European silver can be distinguished from Mexican and Andean metal. European silver dominated Spanish coinage until Philip III, but had, 80 y later after the reign of Philip V, been flushed from the monetary mass and replaced by Mexican silver. PMID:21606351

  11. Proceedings of the 18th Annual Conference on Fossil Energy Materials.

    SciTech Connect

    Judkins, RR

    2004-11-02

    The 18th Annual conference on Fossil Energy Materials was held in Knoxville, Tennessee, on June 2 through June 4, 2004. The meeting was sponsored by the U.S. Department of Energy's (DOE) Office of Fossil Energy through the Advanced Research Materials Program (ARM). The objective of the ARM Program is to conduct research and development on materials for longer-term fossil energy applications, as well as for generic needs of various fossil fuel technologies. The management of the program has been decentralized to the DOE Oak Ridge Operations Office and Oak Ridge National Laboratory (ORNL). The research is performed by staff members at ORNL and by researchers at other national laboratories, universities, and in private industry. The work is divided into the following categories: (1) structural, ceramics, (2) new alloys and coatings, (3) functional materials, and (4) technology development and transfer.

  12. To feel what others feel: two episodes from 18th century medicine.

    PubMed

    Justman, Stewart

    2011-06-01

    In the late 18th century two medical fashions--Mesmerism in France and the Perkins 'tractor' in the USA and England--appealed to the principle that a single universal force acts on all of us and is responsible for health and illness. This principle served both fashions well, as it made it all the easier for those who came within their force fields to experience the sort of sensations that other subscribers to the fashion also seemed to feel. The first research on what is now known as the placebo effect was in connection with these two movements. The propensity to feel what we suppose or imagine that others like us feel remains even now one of the channels of the placebo effect. PMID:21515551

  13. Proceedings of the 18th annual meeting of Japanese Society for Biological Sciences in Space.

    PubMed

    2004-11-01

    This issue contains the proceedings from the 18th annual meeting of the Japanese Society for Biological Sciences in Space, which was held at Fujita Health University, September 30-October 2, 2004. This includes papers from seven symposia: Present Status of the ISS Centrifuge and Its Scientific Goal, Strategy of Frontier Organisms--Plant Growth and Gravi-reception System, Animal Experiment in Space--Scientific Needs and Concerns, Scientific Significance of Biological Effects of Space Radiation, Adaptation of Animal Cells Against Gravity: Dynamics of Proteins and Fiber System, Growth and Gravity--How Has Gravity Associated Homeostasis Evolved and Developed?, and Tenth Anniversary of IML-2 and Its Follow-on Studies. In addition to the symposia papers, 26 general science papers from the annual meeting are included. PMID:15887354

  14. Six calendar systems in the European history from 18^{th} to 20^{th} Century

    NASA Astrophysics Data System (ADS)

    Theodossiou, Efstratios; Manimanis, Vassilios N.; Dimitrijević, Milan S.

    The following calendar systems, introduced in Europe from 18^{th} to 20^{th} century, which were in use for a shorter or longer period by a larger or smaller community, were reviewed and discussed: The French Revolutionary Calendar, the Theosebic calendar invented by Theophilos Kairis, the Revolutionary Calendar of the Soviet Union (or 'Bolshevik calendar'), the Fascist calendar in Italy and the calendar of the Metaxas dictatorship in Greece before World War II. Also the unique of them, which is still in use, the New Rectified Julian calendar of the Orthodox Church, adopted according to proposition of Milutin Milanković on the Congress of Orthodox Churches in 1923 in Constantinople, is presented and discussed. At the end, difficulties to introduce a new calendar are discussed as well.

  15. Preface of the 18th International Conference on Molecular Beam Epitaxy (MBE 2014)

    NASA Astrophysics Data System (ADS)

    Brown, April S.; Ptak, Aaron J.

    2015-09-01

    The first International Conference on Molecular Beam Epitaxy (IC-MBE) was held in Paris in 1978, chaired by Alfred Y. Cho. Every other year since, with the exception of a four-year break after the initial meeting, the IC-MBE has been held in European, Asian, and North American venues. The 18th and latest IC-MBE was held in Flagstaff, Arizona, USA, September 7-12, 2014, and was chaired by Yong-Hang Zhang (Arizona State University). MBE is an advanced crystal growth method that benefits areas from the study of fundamental physics, all the way through the production of devices used in countless fields. IC-MBE brings together researchers from all over the world, and is the premier forum for scientific and technological exchange among researchers investigating all types of materials growth using the MBE technique.

  16. Chemistry Everywhere. The 18th Biennial Conference on Chemical Education, Iowa State University, July 18-22, 2004

    NASA Astrophysics Data System (ADS)

    Burke, K. A.; Freilich, Mark; Greenbowe, Thomas J.; Harwood, William S.

    2004-04-01

    This article provides an overview of the upcoming 18th Biennial Conference on Chemical Education (BCCE) to be held on the campus of Iowa State University, Ames, Iowa, July 18-22, 2004. The report includes details of conference registration, campus housing, campus dining, off-campus housing, tours, social activities, plenary speakers, the conference banquet, travel, and Sci-Mix. The 18th BCCE is using an online abstract submission system, registration and campus housing, and campus dining system. Everything about the conference can be found at the conference Web site (accessed Mar 2004).

  17. Philadelphia

    Atmospheric Science Data Center

    2014-05-15

    ... to avoid the crowds and main roads is the Coastal Heritage Trail, a 440-kilometer (273-mile) collection of historic and other points of ... Service and the state of New Jersey. A portion of the Appalachian Mountains in Pennsylvania is captured in the upper left corner. The ...

  18. Parameterization of 18th January 2011 earthquake in Dalbadin Region, Southwest Pakistan

    NASA Astrophysics Data System (ADS)

    Shafiq-Ur-Rehman; Azeem, Tahir; Abd el-aal, Abd el-aziz Khairy; Nasir, Asma

    2013-12-01

    An earthquake of magnitude 7.3 Mw occurred on 18th January 2011 in Southwestern Pakistan, Baluchistan province (Dalbadin Region). The area has complex tectonics due to interaction of Indian, Eurasian and Arabian plates. Both thrust and strike slip earthquakes are dominant in this region with minor, localized normal faulting events. This earthquake under consideration (Dalbadin Earthquake) posed constraints in depth and focal parameters due to lack of data for evaluation of parameters from Pakistan, Iran or Afghanistan region. Normal faulting mechanism has been proposed by many researchers for this earthquake. In the present study the earthquake was relocated using the technique of travel time residuals. Relocated coordinates and depth were utilized to calculate the focal mechanism solution with outcome of a dominant strike slip mechanism, which is contrary to normal faulting. Relocated coordinates and resulting mechanism are more reliable than many reporting agencies as evaluation in this study is augmented by data from local seismic monitoring network of Pakistan. The tectonics in the area is governed by active subduction along the Makran Subduction Zone. This particular earthquake has strike slip mechanism due to breaking of subducting oceanic plate. This earthquake is located where oceanic lithosphere is subducting along with relative movements between Lut and Helmand blocks. Magnitude of this event i.e. Mw = 7.3, re evaluated depth and a previous study of mechanism of earthquake in same region (Shafiq et al., 2011) also supports the strike slip movement.

  19. [Public health services and healthcare workforce in Bakar of the 18th and 19th century].

    PubMed

    Čulina, Tatjana

    2014-01-01

    This review article draws on scarce and poorly studied archival information and several published articles to describe the development and organisation of public health services in the town of Bakar over the 18th and 19th century. For a short while at the turn of the 19th century, Bakar established a hospital run by two physicians and one surgeon to treat patients affected by the so called Škrljevo disease, an endemic type of syphilis. As the century went on, the number of healthcare providers increased by two more physicians, four surgeons, and three to six licensed midwives. There was also a town pharmacy, that worked all that time. As a busy port, the town also provided well-organised maritime sanitary services. As its economy changed over the two centuries to come to a halt after an initial boom, which resulted in a severe drop in population from 7600 to 2000 people, public services deteriorated, including public health. Maritime services suffered the hardest blow, while the workforce gradually came down to one or two physicians and surgeons and several midwives. PMID:25632775

  20. Analysis of Time Data in Chinese Astronomical Almanacs of the Late 18th Century

    NASA Astrophysics Data System (ADS)

    Lee, K.-W.; Mihn, B.-H.; Ahn, Y. S.; Choi, G.-E.

    2012-09-01

    We investigated the time data in Chinese astronomical almanacs of the late 18th century in order to estimate the accuracy of the Shixian calendar. It is known that the calendar was enforced during the period of the Ching dynasty (1664--1912), and several astronomical almanacs using the calendar are preserved in the Kyujanggak Institute for Korean Studies of Korea; these almanacs cover the years 1772, 1773, 1774, 1780, 1781, 1783, 1785, and 1787. We compiled the times of the new moon, sunrise/sunset, and twenty-four seasonal subdivisions from the almanacs and compared them with the results of modern calculations. As a result, we found that the times of the new moon and twenty-four seasonal subdivisions show average differences of ˜ 3.35 ± 4.43 and ˜ 9.67± 13.24 min, respectively. Regarding he sunrise/sunset time, however, we found that the difference was less than 1 min when we defined the time as the moment that the zenith distance (z) of the Sun is 90°, unlike the modern definition, z=90° 50'. We expect that this study to contribute to the understanding of the accuracy obtained by Shixian calendar in calculations of the movements of celestial bodies.

  1. Two positive tuberculosis cases in the late Nigrovits family, 18th century, Vác, Hungary.

    PubMed

    Szikossy, Ildikó; Pálfi, György; Molnár, Erika; Karlinger, Kinga; Kovács, Balázs K; Korom, Csaba; Schultz, Michael; Schmidt-Schultz, Tyede H; Spigelman, Mark; Donoghue, Helen D; Kustár, Ágnes; Pap, Ildikó

    2015-06-01

    Two mummies of the Hungarian mummy collection from Vác were the subjects of anthropological, paleopathological, radiological, paleomicrobiological, paleohistological and paleoproteomic studies. Both individuals belonged to the same family. The father, József Nigrovits (No 29), died at the age of 55 on the 11th of November 1793; his son, Antal Nigrovits (No 54), died on the 16th of July 1803, at the age of 22. They lived in the 18th century in Vác, a small town in northern Hungary. The macroscopic examination of the son showed a severely deformed neck and back region; the father has no visible mark of any illnesses. As earlier researches showed that tuberculosis was widespread in the community, the etiology of these deformities was examined. The paleomicrobiological results found that both individuals were infected with tuberculosis. Although they suffered from TB, the CT scan data of the bodies and their 3D reconstructions showed no skeletal evidence of tuberculosis. The deformity of the son turned to be a developmental abnormality of unknown origin, but no Pott's gibbus was present. PMID:25814300

  2. Climate and history in the late 18th and early 19th centuries

    NASA Astrophysics Data System (ADS)

    Feldman, Theodore S.

    As in many areas of human knowledge, the notion of climate acquired a deeper historical content around the turn of the 19th century. Natural philosophers, geographers, and others became increasingly aware of climate's own history and its relation to human, plant and animal, and Earth history. This article examines several aspects of this “historicization” of climate.The lively 18th century discussion of the influence of climate on society is well known. Montesquieu is its most famous representative, but Voltaire, Hume, Kant, and others also participated. Their debate was literary more than scientific, their goal the understanding of man, not climate. Partly for this reason and partly because of the lack of good information on climates, they made no attempt to gather substantial climatic data. In fact, the importance of systematically collecting reliable data was scarcely understood in any area of natural philosophy before the last decades of the century [Cf. Frängsmyr et al., 1990; Feldman, 1990]. Instead, participants in the debate repeated commonplaces dating from Aristotle and Hippocrates and based their conclusions on unreliable reports from travelers. As Glacken wrote of Montesquieu, “his dishes are from old and well-tested recipes” [Glacken, 1967, chapter 12]. This is not to say that the debate over climatic influence was not significant—only that its significance lay more in the history of man than in the atmospheric sciences.

  3. Interior view; Street Car Waiting House North Philadelphia Station, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view; Street Car Waiting House - North Philadelphia Station, Street Car Waiting House, 2900 North Broad Street, on northwest corner of Broad Street & Glenwood Avenue, Philadelphia, Philadelphia County, PA

  4. 11. SOUTH (REAR) ELEVATION OF THE PHILADELPHIA SAVING FUND SOCIETY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. SOUTH (REAR) ELEVATION OF THE PHILADELPHIA SAVING FUND SOCIETY (PSFS) BUILDING WITH MEETING HOUSE CORNICE IN FOREGROUND. - Twelfth Street Meeting House, 20 South Twelfth Street, Philadelphia, Philadelphia County, PA

  5. 42. Drawing entitled Atwater Kent Mfg. Co., Philadelphia, Pa., Plant ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. Drawing entitled Atwater Kent Mfg. Co., Philadelphia, Pa., Plant No. 7, Office Entrances, Wissahickon Avenue. The Ballinger Company - Atwater Kent Manufacturing Company, North Plant, 5000 Wissahickon Avenue, Philadelphia, Philadelphia County, PA

  6. 41. Drawing entitled Atwater Kent Mfg. Co., Philadelphia, Pa., Plant ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. Drawing entitled Atwater Kent Mfg. Co., Philadelphia, Pa., Plant No. 7, Elevation and Plan of Bridge. The Ballinger Company (1928) - Atwater Kent Manufacturing Company, North Plant, 5000 Wissahickon Avenue, Philadelphia, Philadelphia County, PA

  7. 38. Drawing entitled Atwater Kent Mfg. Co., Philadelphia, Pa., Plant ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. Drawing entitled Atwater Kent Mfg. Co., Philadelphia, Pa., Plant No. 7, First Story. The Ballinger Company (1928) - Atwater Kent Manufacturing Company, North Plant, 5000 Wissahickon Avenue, Philadelphia, Philadelphia County, PA

  8. 1. BEGINNING OF RAILWAY SUPERSTRUCTURE IN PHILADELPHIA COUNTY. FACING EAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. BEGINNING OF RAILWAY SUPERSTRUCTURE IN PHILADELPHIA COUNTY. FACING EAST DOWN MARKET STREET. - Market Street Elevated Railway, Market Street between Sixty-ninth & Forty-sixth Streets, Philadelphia, Philadelphia County, PA

  9. 5. AERIAL VIEW LOOKING NORTH SHOWING PHILADELPHIA MUSEUM OF ART, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. AERIAL VIEW LOOKING NORTH SHOWING PHILADELPHIA MUSEUM OF ART, SITE OF FORMER MAIN STORAGE RESERVOIR - Fairmount Waterworks, East bank of Schuylkill River, Aquarium Drive, Philadelphia, Philadelphia County, PA

  10. 2. Photocopy of photograph (from Moses King, Philadelphia and Notable ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of photograph (from Moses King, Philadelphia and Notable Philadelphians , 1902, p. 260) OBLIQUE VIEW, SHOWING SOUTH (FRONT) AND EAST(SIDE) ELEVATIONS - Old U.S. Mint, Chestnut & Juniper Streets, Philadelphia, Philadelphia County, PA

  11. Comprehensive District Reform: Philadelphia's Grand Experiment.

    ERIC Educational Resources Information Center

    Useem, Elizabeth; Balfanz, Robert

    2002-01-01

    This report describes "Philadelphia's Grand Experiment" in comprehensive school district reform, from its conception through its initial months of implementation. In 2001, as part of the remedy for low student performance, the governor ordered the state to take over governance of the Philadelphia School District, with a substantial number of…

  12. Philadelphia Youth Network. 2005 Annual Report

    ERIC Educational Resources Information Center

    Philadelphia Youth Network, 2005

    2005-01-01

    This paper presents the annual report of the Philadelphia Youth Network (PYN) for 2005. Throughout the year, PYN's members continued their focus on linking work and education in ways that promote access for young people to Philadelphia's growth economy, and supply a high-quality workforce to power the City's continued economic development. [For…

  13. Philadelphia Alternative Diploma Project. 1996-1997.

    ERIC Educational Resources Information Center

    Philadelphia School District, PA.

    A project was conducted in Philadelphia to help adult students obtain a high school diploma as an alternative to or enhancement of a General Educational Development (GED) certificate. During fiscal year 1996-97 the Metropolitan Career Center (MCC), in collaboration with the School District of Philadelphia, designed an Alternative Diploma Program…

  14. The Struggle To Survive: Work for Racial Ethnic Women in the 18th- and 19th-Century United States.

    ERIC Educational Resources Information Center

    Higginbotham, Elizabeth

    The work situations of Black, Mexican American, and Chinese immigrant women in 18th- and 19th-century United States are explored. Generally, when engaged in agricultural work, all ethnic people were considered units of labor. However, because the slave owner needed to perpetuate his property, Black women were allowed lower rates of production when…

  15. The "System of Chymists" and the "Newtonian Dream" in Greek-Speaking Communities in the 17th-18th Centuries

    ERIC Educational Resources Information Center

    Bokaris, Efthymios P.; Koutalis, Vangelis

    2008-01-01

    The acceptance of new chemical ideas, before the Chemical Revolution of Lavoisier, in Greek-speaking communities in the 17th and 18th centuries did not create a discourse of chemical philosophy, as it did in Europe, but rather a "philosophy" of chemistry as it was formed through the evolution of didactic traditions of Chemistry. This…

  16. [Semantics of learned quackery in the 17th and 18th centuries].

    PubMed

    Füssel, Marian

    2004-06-01

    In the 17th and 18th century republic of letters the problem of scientific fraud was met with a discourse of charlatanism. Departing from Johann Burchhard Menckes famous treatise on the Charlatanry of the learned the following essay traces how the accusations of academic and scientific misconduct put in terms of 'charlatanry' primarily helped to produce the new species of the erudite 'charlatan'. Facing a growing complexity of scientific culture this new frame of meaning, structured by numerous examples of scientific misconduct offered a new way of orientation in the world of learning. But besides its cognitive impacts the discourse of charlatanry allowed to create symbolic boundaries, which determined decisions upon the affiliation or non affiliation to the new forming scientific community by separating honourable from dishonourable scientific personae. Speaking of charlatanry therefore always implied a social distinction as much as a scientific. The discourses on charlatanry also mirror differentiations within the scientific field. At first dominated by a critique built on courteous or bourgeois values, the scientific field later on developed its own criteria of appraisal like authorship, originality, transparency etc. Attracting the attention of a further growing public sphere, the explicit verbalisation of claims not relating to the value system of a republic of letters primarily concerned with the production and distribution of knowledge finally led up to a more implicit moral economy of science. A change that at a large scale level can be described both as an internalisation of the values of scientific conduct and differentiation between justiciable and unjusticiable transgressions of the norms set up by the scientific community. PMID:15338535

  17. Hydro-meteorological extreme events in the 18th century in Portugal

    NASA Astrophysics Data System (ADS)

    Fragoso, Marcelo; João Alcoforado, Maria; Taborda, João Paulo

    2013-04-01

    The present work is carried out in the frame of the KLIMHIST PROJECT ("Reconstruction and model simulations of past climate in Portugal using documentary and early instrumental sources, 17th-19th century)", and is devoted to the study of hydro-meteorological extreme events during the last 350 years, in order to understand how they have changed in time and compare them with current analogues. More specifically, the results selected to this presentation will focus on some hydro-meteorological extreme events of the 18th century, like severe droughts, heavy precipitation episodes and windstorms. One of the most noteworthy events was the winterstorm Bárbara (3rd to 6th December 1739), already studied in prior investigations (Taborda et al, 2004; Pfister et al, 2010), a devastating storm with strong impacts in Portugal caused by violent winds and heavy rainfall. Several other extreme events were detected by searching different documentary archives, including individual, administrative and ecclesiastic sources. Moreover, a more detailed insight to the 1783-1787 period will be made with regard the Lisbon region, taking into consideration the availability of information for daily meteorological observations as well as documentary evidences, like descriptions from Gazeta de Lisboa, the periodic with more continuous publication in the 18thcentury. Key-words: Instrumental data, Documentary data, Extreme events, Klimhist Project, Portugal References Pfister, C., Garnier, E., Alcoforado, M.J., Wheeler, D. Luterbacher, J. Nunes, M.F., Taborda, J.P. (2010) The meteorological framework and the cultural memory of three severe winter-storms in early eighteenth-century Europe, Climatic Change, 101, 1-2, 281-310 Taborda, JP; Alcoforado, MJ and Garcia, JC (2004) O Clima do Sul de Portugal no Séc.XVIII, Centro de Estudos Geográficos, Área de de Investigação de Geo-Ecologia, relatório no 2

  18. Synthesis of calcium antimonate nano-crystals by the 18th dynasty Egyptian glassmakers

    NASA Astrophysics Data System (ADS)

    Lahlil, S.; Biron, I.; Cotte, M.; Susini, J.; Menguy, N.

    2010-01-01

    During the 18th Egyptian dynasty (1570-1292 B.C.), opaque white, blue and turquoise glasses were opacified by calcium antimonate crystals dispersed in a vitreous matrix. The technological processes as well as the antimony sources used to manufacture these crystals remain unknown. Our results shed a new light on glassmaking history: contrary to what was thought, we demonstrate that Egyptian glassmakers did not use in situ crystallization but first synthesized calcium antimonate opacifiers, which do not exist in nature, and then added them to a glass. Furthermore, using transmission electron microscopy (TEM) for the first time in the study of Egyptian opaque glasses, we show that these opacifiers were nano-crystals. Prior to this research, such a process for glassmaking has not been suggested for any kind of ancient opaque glass production. Studying various preparation methods for calcium antimonate, we propose that Egyptian craftsmen could have produced Ca2Sb2O7 by using mixtures of Sb2O3 or Sb2O5 with calcium carbonates (atomic ratio Sb/Ca=1) heat treated between 1000 and 1100°C. We developed an original strategy focused on the investigation of the crystals and the vitreous matrices using an appropriate suite of high-sensitivity and high-resolution micro- and nano-analytical techniques (scanning electron microscopy (SEM), X-ray diffraction (XRD), TEM). Synchrotron-based micro X-ray absorption near edge spectroscopy (μ-XANES) proved to be very well suited to the selective measure of the antimony oxidation state in the vitreous matrix. This work is the starting point for a complete reassessment not only of ancient Egyptian glass studies but more generally of high-temperature technologies used throughout antiquity.

  19. A comparison of large 18th-century floods on Danube: Vienna - Bratislava - Budapest

    NASA Astrophysics Data System (ADS)

    Kiss, Andrea; Parajka, Juraj

    2013-04-01

    The documentation of historic floods can help in better understanding of factors that might cause and contribute to large and extreme flood events. In particular, the analysis of historic floods provides information about flood seasonality, its changes and anthropogenic impacts on river flood regime which in some cases strongly influenced flood behaviour. The main objective of the present contribution is to document large and medium size flood events on Danube in Vienna, Bratislava and Budapest in the 18th century. In the present study, based on contemporary documentary evidence, for each of the three towns a five-scaled flood index series is developed to describe the magnitude and intensity of flood events. According to this classification, the 100-year flood event was characterised by the index value 5, while great destructive floods - depending on their extension, destructivity and further impacts - received the values 4 and 3, respectively. Less significant but still harmful flood events were classified as No. 2, and floods without further specification remained in the lowest category (No. 1). Beside classification issues, seasonality and flood frequency differences between the three towns are as well discussed. The results indicate that a greater number of flood events took place in the last decades of the century, but only a few flood events of the same magnitude are documented simultaneously in all three towns. And whereas in 1775 no winter flood event was reported in Vienna, an important ice jam flood was documented in Bratislava, and a catastrophic ice jam flood event, greatest of the century, occurred in Budapest. In 1787 autumn the greatest flood event of the century occurred in Vienna, while hardly any flood waves were observed at Budapest. While in Vienna, summer (and partly autumn) floods had great importance, in Budapest a large number of ice jam floods were documented. In some cases the differences are likely caused by different hydrometeorological

  20. Philadelphia Printing and Publishing, 1876-1976

    ERIC Educational Resources Information Center

    Whitehead, Thomas M.

    1976-01-01

    Two Philadelphia printing histories, both reflecting the relationship of printing to publishing, are examined in this article: the manufacture by the publisher of his own product and the development and commercialization of the photomechanical halftone process. (Author)

  1. COMPOSITE RECEPTOR METHOD APPLIED TO PHILADELPHIA AEROSOL

    EPA Science Inventory

    Particles were collected in dichotomous samplers at three sites in the Philadelphia area during summer, 1982, and analyzed by x-ray fluorescence, instrumental neutron activation, pyrolysis, and ion chromatography. An intermethod comparison showed that fine fraction results agreed...

  2. Philadelphia Eagles Honor NASA Astronaut Chris Ferguson

    NASA Video Gallery

    NASA astronaut Chris Ferguson returned to his hometown on Nov. 7 to serve as the Philadelphia Eagles' Honorary Captain during the NFL's "Monday Night Football" game. The Eagles hosted the Chicago B...

  3. The historical archaeology of the 17th- and 18th-century Jewish community of Nevis, British West Indies

    NASA Astrophysics Data System (ADS)

    Terrell, Michelle M.

    2000-11-01

    This is an historical archaeological examination of a 17th- and 18th-century Jewish community on the island of Nevis in the British West Indies. Unlike earlier archaeological studies of the Jewish Caribbean Diaspora that focused on single sites, this investigation used a community-wide approach to elucidate the daily experience of Sephardic Jews within the colonial Caribbean. This project included an archaeological excavation at the purported location of the community's synagogue, an electrical resistivity survey of the surviving cemetery, the construction of a map of property ownership in 18th-century Charlestown, and archival research. This study was carded out within a multiscalar and contextual framework that emphasized the importance of understanding the diaspora that brought the Jews to the West Indies, the development of the colonial Caribbean, and the surrounding environs of the port city of Charlestown, Nevis. The archaeological analysis of the supposed site of the synagogue proved that it was in fact that of a late 18th-century townhouse, but the associated land record research revealed the actual location of the community's former synagogue. Furthermore, the reconstruction of the physical layout of colonial-period Charlestown from the land records indicated the presence of a distinct Jewish quarter in the undesirable southern portion of the town. Evidence from the public records of Nevis and the social history of the members of the Jewish population unveiled external social and political pressures placed upon the Sephardim as well as internal religious and ethnic ties dig bound the community together. It is argued in closing that the archival evidence, in conjunction with the continued presence of a clustered settlement pattern like that of European Jewish communities during the medieval period, indicates that the Jews of the Caribbean were not fully integrated socially or politically into British colonial society. This examination of the Nevis community

  4. Non Destructive Investigation on the 17th/18th Century Sicilian Jewellery Collection at the Messina Regional Museum Using Mobile Raman Equipment

    NASA Astrophysics Data System (ADS)

    Barone, G.; Bersani, D.; Jehlicka, J.; Lottici, P. P.; Mazzoleni, P.; Raneri, S.; Vandenabeele, P.; Di Giacomo, C.; Larinà, G.

    2014-06-01

    A handheld Raman spectrometer operating at 785 nm was used for the in situ analysis of the gems present in the 17th/18th century Sicilian jewelry collection preserved in the Messina Regional Museum (Italy).

  5. Promoting alternative fuels in Philadelphia. Final report

    SciTech Connect

    1996-04-16

    The US Department of Energy`s grant to Citizens Fund was designed to support a grassroots organizing campaign, local coalition building and media activity initially focused on getting the Southeastern Pennsylvania Transit Authority (SEPTA) to acquire clean burning alternative fueled buses (e.g. natural gas). In addition, Citizens Fund through Pennsylvania Citizen Action would become involved in the Philadelphia Clean Cities organization sponsored by the City of Philadelphia through a DOE grant. The city reached out to a substantial number of organizations and community leaders and actively worked to get out the message on the need to promote and use alternatively-fueled vehicles. This report summarizes these activities.

  6. Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy

    PubMed Central

    Feldman, Michal; Hershkovitz, Israel; Sklan, Ella H.; Kahila Bar-Gal, Gila; Pap, Ildikó; Szikossy, Ildikó; Rosin-Arbesfeld, Rina

    2016-01-01

    Mutations of the Adenomatous polyposis coli (APC) gene are common and strongly associated with the development of colorectal adenomas and carcinomas. While extensively studied in modern populations, reports on visceral tumors in ancient populations are scarce. To the best of our knowledge, genetic characterization of mutations associated with colorectal cancer in ancient specimens has not yet been described. In this study we have sequenced hotspots for mutations in the APC gene isolated from 18th century naturally preserved human Hungarian mummies. While wild type APC sequences were found in two mummies, we discovered the E1317Q missense mutation, known to be a colorectal cancer predisposing mutation, in a large intestine tissue of an 18th century mummy. Our data suggests that this genetic predisposition to cancer already existed in the pre-industrialization era. This study calls for similar investigations of ancient specimens from different periods and geographical locations to be conducted and shared for the purpose of obtaining a larger scale analysis that will shed light on past cancer epidemiology and on cancer evolution. PMID:26863316

  7. 14. LION SCULPTURE, AT THE PHILADELPHIA MUSEUM OF ART, MOVED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. LION SCULPTURE, AT THE PHILADELPHIA MUSEUM OF ART, MOVED FROM MERCHANTS' EXCHANGE, WHERE IT RESTED ON THE STAIR WALL OF SIDE ENTRANCE STAIRS. (A REPLACEMENT LION HAS BEEN PLACED IN THE ORIGINAL SITE, AS DID ANOTHER REPLACEMENT IN THE OTHER SIDE OF THE BUILDING. FOR THIS LATTER REPLACEMENT SEE PA-1028-15). A VIEW OF THE MUSEUM IS IN THE BACKGROUND - Philadelphia Exchange Company, 143 South Third Street, Philadelphia, Philadelphia County, PA

  8. Affective Education in Philadelphia. Fastback 102.

    ERIC Educational Resources Information Center

    Newberg, Norman A.

    This small booklet describes the Affective Education Program established in Philadelphia in 1967. The program uses various classroom techniques such as the problems, plans, and sharing classroom structure to foster student leadership and cooperation; using group roles, feedback, and processing; and being responsive to student concerns. In…

  9. Philadelphia's Teacher Appraisal System Needs Improvement

    ERIC Educational Resources Information Center

    Royal, Camika; Tossman, Matthew

    2009-01-01

    The purpose of this paper is to inform the community about teacher appraisal methods in the School District of Philadelphia, outline the difficulties of the current system, and suggest approaches that would strengthen the teacher appraisal process. The authors gathered their information over three months in mid-2009 from multiple sources:…

  10. Philadelphia's Independence Starts Here: Disability Arts Festival

    ERIC Educational Resources Information Center

    Smith, Mimi Kenney

    2008-01-01

    In tribute to Philadelphia's world-changing past, Festival partners dubbed the month-long Disability Arts Festival "Independence Starts Here." Through it, they hoped to begin to change the future for over 675,000 people with disabilities in the area and their families. Led by Amaryllis Theatre Company, which now also serves as VSA arts of…

  11. Philadelphia's Renaissance Schools Initiative after Four Years

    ERIC Educational Resources Information Center

    Stratos, Kati; Wolford, Tonya; Reitano, Adrienne

    2015-01-01

    In 2010-2011, the School District of Philadelphia (the District) launched its Renaissance Schools Initiative, a program designed to dramatically improve student achievement in the District's lowest performing schools. Some schools became Promise Academies, based on the federal turnaround model, and remained District-operated neighborhood schools.…

  12. South Philadelphia Passive Sampler and Sensor Study

    EPA Science Inventory

    Starting in June 2013, the United States Environmental Protection Agency (U.S. EPA) and the City of Philadelphia Air Measurements Services began collaborative research on the use of passive samplers (PSs) and stand-alone air measurement (SAM) systems to improve information on the...

  13. Philadelphia, Pennsylvania: Solar in Action (Brochure)

    SciTech Connect

    Not Available

    2011-10-01

    This brochure provides an overview of the challenges and successes of Philadelphia, PA, a 2008 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

  14. [Control discourses and power relations of yellow fever: Philadelphia in 1793].

    PubMed

    Kim, Seohyung

    2014-12-01

    1793 Yellow fever in Philadelphia was the most severe epidemics in the late 18th century in the United States. More than 10% of the population in the city died and many people fled to other cities. The cause of yellow fever in the United States had close relationship with slaves and sugar in Philadelphia. Sugarcane plantation had needed many labors to produce sugar and lots of Africans had to move to America as slaves. In this process, Aëdes aegypti, the vector of yellow fever had migrated to America and the circumstances of ships or cities provided appropriate conditions for its breeding. In this period, the cause of yellow fever could not be established exactly, so suggestions of doctors became entangled in political and intellectual discourses in American society. There was a critical conflict between Jeffersonian Republicanism and Federalism about the origin and treatment of yellow fever. Benjamin Rush, a Jeffersonian Republican, suggested urban sanitation reform and bloodletting. He believed the infectious disease happened because of unsanitary city condition, so he thought the United States could be a healthy nation by improvement of the public health and sanitation. He would like to cope with national crisis and develop American society on the basis of republicanism. While Rush suggested the improvement of public health and sanitation, the city government of Philadelphia suggested isolation of yellow fever patients and quarantine. City government isolated the patients from healthy people and it reconstructed space of hospital. Also, it built orphanages to take care of children who lost their parents during the epidemic and implemented power to control people put in the state of exception. Of course, city government tried to protect the city and nation by quarantine of every ship to Philadelphia. Control policies of yellow fever in 1793 showed different conflicts and interactions. Through the yellow fever, Jeffersonian Republicanism and Federalism had

  15. Real-World Vehicle Emissions: A Summary of the 18th Coordinating Research Council On-Road Vehicle Emissions Workshop

    SciTech Connect

    Cadle, S. H.; Ayala, A.; Black, K. N.; Graze, R. R.; Koupal, J.; Minassian, F.; Murray, H. B.; Natarajan, M.; Tennant, C. J.; Lawson, D. R.

    2009-02-01

    The Coordinating Research Council (CRC) convened its 18th On-Road Vehicle Emissions Workshop March 31-April 2, 2008, with 104 presentations describing the most recent mobile source-related emissions research. In this paper we summarize the presentations from researchers whose efforts are improving our understanding of the contribution of mobile sources to air quality. Participants in the workshop discussed emission models and emissions inventories, results from gas- and particle-phase emissions studies from spark-ignition and diesel-powered vehicles (with an emphasis in this workshop on particle emissions), effects of fuels on emissions, evaluation of in-use emission-control programs, and efforts to improve our capabilities in performing on-board emissions measurements, as well as topics for future research.

  16. Venetian Rule and Control of Plague Epidemics on the Ionian Islands during 17th and 18th Centuries

    PubMed Central

    Konstantinidou, Katerina; Mantadakis, Elpis; Sardi, Thalia; Samonis, George

    2009-01-01

    During the 17th and 18th centuries, measures were taken by the Venetian administration to combat plague on the Ionian Islands. At that time, although the scientific basis of plague was unknown, the Venetians recognized its infectious nature and successfully decreased its spread by implementing an information network. Additionally, by activating a system of inspection that involved establishing garrisons along the coasts, the Venetians were able to control all local movements in plague-infested areas, which were immediately isolated. In contrast, the neighboring coast of mainland Greece, which was under Ottoman rule, was a plague-endemic area during the same period. We conclude that even in the absence of scientific knowledge, close observation and social and political measures can effectively restrain infectious outbreaks to the point of disappearance. PMID:19116047

  17. [Sanitary state of the ships of the Baltic fleet and development of the navy hygiene in the 18th century].

    PubMed

    Kostyuk, A V

    2015-09-01

    Sanitary and hygienic state of the Baltic navy ships in the 18th century was considered as unsatisfactory due to inappropriate habitation conditions answering hygienic requirements. The reason for the low ship habitation of that time was limited technological possibilities of the sail shipbuilding, lack of appropriate labour, and life and rest conditions for navy servicemen. In fact, wooden ships were not suitable for life activity of the navy crew, but contributed to disease increase. Because of the rapid development of the' navy hygiene and improvement of shipbuilding technologies, sanitary and hygienic state of local navy ships had became improving. With a glance on recommendations, developed by physicians D.P.Sinopeus and A.G.Bakherakht, were made following improvements: were implemented ventilators on ships, daily fumigation of ships rooms, monitoring of personal hygiene. PMID:26827523

  18. Soil resources and agriculture in the center of European Russia at the end of the 18th century

    NASA Astrophysics Data System (ADS)

    Alyabina, I. O.; Golubinsky, A. A.; Kirillova, V. A.; Khitrov, D. A.

    2015-11-01

    Soil-geographic and socioeconomic data were compared with the use of geoinformation technologies. The history of agricultural development of the East European Plain and distribution of population in Russia in the 18th century were studied by the example of Yaroslavl, Vladimir, and Ryazan gubernias (governorates). The analysis of the obtained data demonstrated considerable differences in land uses between the regions of the old (prior to the 16th century) development and the regions actively populated since the end of the 16th century. The soils of Vladimir and a half of Yaroslavl gubernias were most developed; in some local districts (uezds), the maximum possible efficiency of the use of the natural soil fertility was achieved. In contrast, in some chernozemic areas, considerable opportunities for the further extensive development were preserved, and the limits to the population growth were not reached. The level of agricultural loads on the territory remained relatively low.

  19. Metallographic study of articles of the Kamensk iron foundry and iron works produced in the 18th-20th centuries

    NASA Astrophysics Data System (ADS)

    Schastlivtsev, V. M.; Gizhevski, B. A.; Khlebnikova, Yu. V.; Naumov, S. V.; Egorova, L. Yu.

    2016-02-01

    Results have been presented for studies of the microstructure and chemical composition of a number of articles made of iron and cast iron at the Kamensk plant, which cover the period from the start of the production of iron on the territory of the city of Kamensk-Ural'skii at the turn of the 17th-18th centuries to the beginning of the 20th century. Differences in the composition of the Kamensk cast iron and modern grades of foundry cast iron have been established. Possible sources of technological difficulties and production waste at the Kamensk plant have been revealed. The potential of metallographic studies for the attribution of historical articles made of ferrous metals are shown.

  20. Venetian rule and control of plague epidemics on the Ionian Islands during 17th and 18th centuries.

    PubMed

    Konstantinidou, Katerina; Mantadakis, Elpis; Falagas, Matthew E; Sardi, Thalia; Samonis, George

    2009-01-01

    During the 17th and 18th centuries, measures were taken by the Venetian administration to combat plague on the Ionian Islands. At that time, although the scientific basis of plague was unknown, the Venetians recognized its infectious nature and successfully decreased its spread by implementing an information network. Additionally, by activating a system of inspection that involved establishing garrisons along the coasts, the Venetians were able to control all local movements in plague-infested areas, which were immediately isolated. In contrast, the neighboring coast of mainland Greece, which was under Ottoman rule, was a plague-endemic area during the same period. We conclude that even in the absence of scientific knowledge, close observation and social and political measures can effectively restrain infectious outbreaks to the point of disappearance. PMID:19116047

  1. PCR diagnostics of Mycobacterium tuberculosis in historic human long bone remains from 18th century burials in Kaiserebersdorf, Austria

    PubMed Central

    Bachmann, Lutz; Däubl, Barbara; Lindqvist, Charlotte; Kruckenhauser, Luise; Teschler-Nicola, Maria; Haring, Elisabeth

    2008-01-01

    Background In the present pilot study we applied recently published protocols for detecting Mycobacterium tuberculosis in human remains. We screened long bones from an 18th century cemetery and skulls from the anatomical "Weisbach collection" (19th century). In addition, besides the study of abundance of tuberculosis in inmates of the poorhouse itself, we were interested to test whether in this particular instance tuberculosis can be identified from cortical bones, which are rarely affected by tuberculosis, but mostly better preserved than the vertebral bodies or epiphyses. Method The DNA extractions from the bone samples were obtained following established ancient DNA protocols. Subsequently extracts were subjected to a series of PCR amplifications using primer pairs published previously [1,2]. PCR products of the expected size were subsequently sequenced. Results Only primers targeting the repetitive IS6110 insertion sequence yielded PCR products of appropriate size. In one sample only (skull sample WB354 of the "Weisbach collection") sequence analysis revealed an authentic M. tuberculosis sequence that matched to a reference sequence from GenBank. Conclusion With a variety of established PCR approaches we failed to detect M. tuberculosis DNA in historic human femurs from an 18th century cemetery relating to a poor house in Kaiserebersdorf, Austria. Our data may indicate that in this particular case, thoracic or lumbar vertebrae, i.e. bones that are severely affected by the disease, would be more suitable for molecular diagnostics than long bones. However, the unpredictable state of DNA preservation in bones from museum collections does not allow any general recommendation of any type of bone. PMID:18799009

  2. [Development of animal husbandry in Groningen in the 18th and 19th century; a broad outline].

    PubMed

    Paping, R F

    2001-01-01

    This overview is mainly focussed on the clay area forming the northern half of the province. It is the wealthiest and most characteristic part, being cultured since the Middle Ages as testified by the many churches that even small villages were able to construct. About 1700 the province of Groningen enjoyed already a modern economy, fitting in with that of the other coastal areas of Friesland, Zeeland and Holland (the last mentioned was the richest region of the world in the 17th and 18th century). As aspects of modernity at that time can be considered: 1) the use of modern agricultural methods with higher yields per hectare and higher milk yields per cow than produced in the land provinces on the sandy soils; 2) Agriculture was aimed at earning money by selling of hte products. In opposition to the farmers in the land provinces, who mainly produced for subsistence farming, the farmers in the coastal areas produced for the trade; 3) A high degree of specialization was found in the rural areas. 30-40% of the families had own farms, 25% of the population were labourers, owing only small pieces of land and the rest of the working population had occupations outside agriculture (craftmen, shopkeepers, shipmasters, merchants etc.). Whereas on the sandy soils practically every family owned a farm, be it mostly a very small one. After reviewing the changes in the distribution of land in use of the production of fieldcrops or for meadows-always in function of the market value of the products-and after a discussion of type of cattle husbandry (breeding, fattening, dairying) it is concluded that a relative decrease of the importance of cattle husbandry in the clay region during the 18th - 19th century can be observed. Intensification of land use had a positive effect on crop-production. The much-heard opinion that the cattle plague epizootic of 1768-1786 caused a transition in land use through a switch from animal husbandry to arable farming, is not held by the author

  3. Biomechanical beam analysis of long bones from a late 18th century slave cemetery in Cape Town, South Africa.

    PubMed

    Ledger, M; Holtzhausen, L M; Constant, D; Morris, A G

    2000-06-01

    This study aims to quantify the physical demands of a sample of late 18th century skeletons from an unmarked burial site on Cobern Street, Cape Town, South Africa. Historical studies suggest that these individuals were either slaves or "free black" people of low socioeconomic standing. Cortical cross-sectional areas of paired humeri and tibiae from the Cobern Street collection (N = 29), a modern cadaver collection (N = 31), and a hunter-gatherer collection (N = 30) were compared by means of biomechanical beam analysis on computerized tomography scans. Results showed that the Cobern Street sample, both males and females, were closer to the modern group in total tibial cortical area and in the second moments and polar moments of cortical area, than to the hunter-gatherer group. It is assumed that these results can be explained by differences in lower limb activity. Tibial strength properties showed the hunter-gatherer peoples to be highly mobile and active walkers in comparison to the Cobern Street and modern samples. The males from the Cobern Street sample showed significantly higher values for humeral strength properties than either the hunter-gatherer or modern individuals, attesting to their status as manual laborers. The humeral cross-sectional strength properties for females were very similar between the Cobern Street and modern groups but again significantly different from the hunter-gatherer sample. The domestic chores performed by females of the recent cadaver sample may be very similar to those performed by the Cobern Street sample. PMID:10813703

  4. Report on the 18th International Conference on X-ray and Inner-Shell Processes (X99).

    SciTech Connect

    Gemmell, D. S.; Physics

    2000-01-01

    The 18th conference of the series served as a forum for discussing fundamental issues in the field of x-ray and inner-shell processes and their application in various disciplines of science and technology. Special emphasis was given to the opportunities offered by modern synchrotron x-ray sources. The program included plenary talks, progress reports and poster presentations relating to new developments in the field of x-ray and inner-shell processes. The range of topics included: X-ray interactions with atoms, molecules, clusters, surfaces and solids; Decay processes for inner-shell vacancies; X-ray absorption and emission spectroscopy - Photoionization processes; Phenomena associated with highly charged ions and collisions with energetic particles; Electron-spin and -momentum spectroscopy; X-ray scattering and spectroscopy in the study of magnetic systems; Applications in materials science, biology, geosciences, and other disciplines; Elastic and inelastic x-ray scattering processes in atoms and molecules; Threshold phenomena (post-collision interaction, resonant Raman processes, etc.); Nuclear absorption and scattering of x-rays; 'Fourth-generation' x-ray sources; Processes exploiting the polarization and coherence properties of x-ray beams; Developments in experimental techniques (x-ray optics, temporal techniques, detectors); Microscopy, spectromicroscopy, and various imaging techniques; Non-linear processes and x-ray lasers; Ionization and excitation induced by charged particles and by x-rays; and Exotic atoms (including 'hollow' atoms and atoms that contain 'exotic' particles).

  5. Shedding New Light on the 18th Dynasty Mummies of the Royal Architect Kha and His Spouse Merit.

    PubMed

    Bianucci, Raffaella; Habicht, Michael E; Buckley, Stephen; Fletcher, Joann; Seiler, Roger; Öhrström, Lena M; Vassilika, Eleni; Böni, Thomas; Rühli, Frank J

    2015-01-01

    The mummies of Kha and his wife Merit were found intact in an undisturbed tomb in western Thebes near the ancient workers' village of Deir el-Medina. Previous MDCT (this abbreviation needs spelling out) investigations showed that the bodies of Kha and Merit did not undergo classical royal 18th Dynasty artificial mummification, which included removal of the internal organs. It was, therefore, concluded that the retention of the viscera in the body, combined with an absence of canopic jars in the burial chamber, meant the couple underwent a short and shoddy funerary procedure, despite their relative wealth at death. Nevertheless, all internal organs - brain, ocular bulbs/ocular nerves, thoracic and abdominal organs - showed a very good state of preservation, which contradicts the previous interpretation above. In order to better understand the type of mummification used to embalm these bodies, both wrapped mummies were reinvestigated using new generation X-ray imaging and chemical microanalyses Here we provide evidence that both individuals underwent a relatively high quality of mummification, fundamentally contradicting previous understanding. Elucidated "recipes", whose components had anti-bacterial and anti-insecticidal properties, were used to treat their bodies. The time and effort undoubtedly employed to embalm both Kha and Merit and the use of imported costly resins, notably Pistacia, do not support the previously held view that the two individuals were poorly mummified. Despite a lack of evisceration, the approach clearly allowed their in situ preservation as well as affording a fairly successful mummification. PMID:26200778

  6. Shedding New Light on the 18th Dynasty Mummies of the Royal Architect Kha and His Spouse Merit

    PubMed Central

    Bianucci, Raffaella; Habicht, Michael E.; Buckley, Stephen; Fletcher, Joann; Seiler, Roger; Öhrström, Lena M.; Vassilika, Eleni; Böni, Thomas; Rühli, Frank J.

    2015-01-01

    The mummies of Kha and his wife Merit were found intact in an undisturbed tomb in western Thebes near the ancient workers’ village of Deir el-Medina. Previous MDCT (this abbreviation needs spelling out) investigations showed that the bodies of Kha and Merit did not undergo classical royal 18th Dynasty artificial mummification, which included removal of the internal organs. It was, therefore, concluded that the retention of the viscera in the body, combined with an absence of canopic jars in the burial chamber, meant the couple underwent a short and shoddy funerary procedure, despite their relative wealth at death. Nevertheless, all internal organs - brain, ocular bulbs/ocular nerves, thoracic and abdominal organs - showed a very good state of preservation, which contradicts the previous interpretation above. In order to better understand the type of mummification used to embalm these bodies, both wrapped mummies were reinvestigated using new generation X-ray imaging and chemical microanalyses Here we provide evidence that both individuals underwent a relatively high quality of mummification, fundamentally contradicting previous understanding. Elucidated “recipes”, whose components had anti-bacterial and anti-insecticidal properties, were used to treat their bodies. The time and effort undoubtedly employed to embalm both Kha and Merit and the use of imported costly resins, notably Pistacia, do not support the previously held view that the two individuals were poorly mummified. Despite a lack of evisceration, the approach clearly allowed their in situ preservation as well as affording a fairly successful mummification. PMID:26200778

  7. The initial giant umbrella cloud of the May 18th, 1980, explosive eruption of Mount St. Helens

    USGS Publications Warehouse

    Sparks, R.S.J.; Moore, J.G.; Rice, C.J.

    1986-01-01

    The initial eruption column of May 18th, 1980 reached nearly 30 km altitude and released 1017 joules of thermal energy into the atmosphere in only a few minutes. Ascent of the cloud resulted in forced intrusion of a giant umbrella-shaped cloud between altitudes of 10 and 20 km at radial horizontal velocities initially in excess of 50 m/s. The mushroom cloud expanded 15 km upwind, forming a stagnation point where the radial expansion velocity and wind velocity were equal. The cloud was initiated when the pyroclastic blast flow became buoyant. The flow reduced its density as it moved away from the volcano by decompression, by sedimentation, and by mixing with and heating the surrounding air. Observations indicate that much of the flow, covering an area of 600 km2, became buoyant within 1.5 minutes and abruptly ascended to form the giant cloud. Calculations are presented for the amount of air that must have been entrained into the flow to make it buoyant. Assuming an initial temperature of 450??C and a magmatic origin for the explosion, these calculations indicate that the flow became buoyant when its temperature was approximately 150??C and the flow consisted of a mixture of 3.25 ?? 1011 kg of pyroclasts and 5.0 ?? 1011 kg of air. If sedimentation is considered, these figures reduce to 1.1 ?? 1011 kg of pyroclasts and 1.0 ?? 1011 kg of air. ?? 1986.

  8. Evidence for tuberculosis in 18th/19th century slaves in Anse Sainte-Marguerite (Guadeloupe - French Western Indies).

    PubMed

    Lösch, Sandra; Kim, Mi-Ra; Dutour, Olivier; Courtaud, Patrice; Maixner, Frank; Romon, Thomas; Sola, Christophe; Zink, Albert

    2015-06-01

    During the American colonization in the 18th and 19th century, Africans were captured and shipped to America. Harsh living and working conditions often led to chronic diseases and high mortality rates. Slaves in the Caribbean were forced to work mainly on sugar plantations. They were buried in cemeteries like Anse Sainte-Marguerite on the isle of Grande-Terre (Guadeloupe) which was examined by archaeologists and physical anthropologists. Morphological studies on osseous remains of 148 individuals revealed 15 cases with signs for bone tuberculosis and a high frequency of periosteal reactions which indicates early stages of the disease. 11 bone samples from these cemeteries were analysed for ancient DNA. The samples were extracted with established procedures and examined for the cytoplasmic multicopy β-actin gene and Mycobacterium tuberculosis complex DNA (IS 6110) by PCR. An amplification product for M. tuberculosis with the size of 123 bp was obtained. Sequencing confirmed the result. This study shows evidence of M. tuberculosis complex DNA in a Caribbean slave population. PMID:25754341

  9. [The creation of hospitals by charities in Minas Gerais (Brazil) from 18th to 20th century].

    PubMed

    Marques, Rita de Cássia

    2011-01-01

    This article is the fruit of research into the cultural heritage of healthcare in Minas Gerais (Brazil) and explores the construction of hospitals supported by Catholic charities from the 18th to 20th century. Catholicism has always been strong in Minas Gerais, partly because the Portuguese Crown prohibited the free travel of priests, who were suspected of illegally trading in gold from the mines. A brotherhood was responsible for creating the first Santa Casa, in Vila Rica. Another very important religious group in Brazil, the Vincentians, was also devoted to charitable works and propagated the ideas on charity of Frederico Ozanan, based on the work of St. Vincent de Paul. This group comprised both a lay movement, supported by conferences organized by the St. Vincent de Paul Society, and a religious order, the Vincentian priests and nuns. Catholic physicians make up the third group studied here, organized in a professional association promoted by the Catholic Church. The brotherhoods, Vincentians, and associations, with their Santa Casas, represent a movement that is recognized worldwide. The enormous Catholic participation in these charitable works brought in the physicians, who would often make no charge and exerted efforts to create hospitals that served the population. Although the capital of Minas Gerais was the creation of republicans and positivists in the 20th century, with their ideas of modernity, it remained dependent on Christian charity for the treatment of the poor. PMID:21936227

  10. (Re)Constructions of Etymology of the Term "Electricity" in French German and Modern Greek Textbooks of Physics of 18th-19th Centuries

    ERIC Educational Resources Information Center

    Patsopoulos, Dimitrios

    2005-01-01

    The different and contrasting versions of the etymology of the term "electricity" in Modern Greek textbooks of Physics of the 18th and 19th century, which are influenced by French and German textbooks, are not mere (re)constructions that serve the didactic purposes and objectives of their authors. They are (in)directly related to the social and…

  11. The conjoined twin sisters Helen and Judith (1701-1723) and their pictorial impact in later 18th-century science.

    PubMed

    van der Weiden, Robin M F; Clausberg, Karl

    2015-08-01

    Given the uniqueness of the Hungarian conjoined twin sisters Helen and Judith (1701–1723) and their lasting influence as an anatomical showcase if not model for mental or social deviant states, we present here a closer scrutiny of their introduction into the scientific literature of the later 18th century by analyzing depictions of the twins from 1707 onwards. PMID:26133671

  12. Impact of Community College of Philadelphia Allied Health Programs on the Philadelphia Region. Report #117.

    ERIC Educational Resources Information Center

    Philadelphia Community Coll., PA.

    This report discusses the Allied Health programs at Community College of Philadelphia (CCP): (1) Clinical Laboratory Technician; (2) Dental Assisting Hygiene; (3) Dental Assisting Certificate; (4) Diagnostic Medical Imaging; (5) Dietetic Technician; (6) Health Information Technology; (7) Medical Assisting and Office Management; (8) Nursing; and…

  13. The construction of the country landscape in Veneto plains (North of Italy) during 18th-21st centuries

    NASA Astrophysics Data System (ADS)

    Borin, Maurizio; Novello, Elisabetta

    2013-04-01

    This paper focuses on the transformation that has taken place in the last four centuries in Veneto's plain in northern Italy. The analysis of statistical data over a long period of time has made it possible to chronologically reconstruct the gradual transformation of wetlands into arable land, suitable for human settlement and for the development of industrial activities. Particularly relevant are the policies adopted by the Republic of Venice (14th-18th centuries) with regard to the management of waters, policies which were continued by the Italian State after its unification in 1861. The evolution of the concept of land reclamation gradually came to include draining, hygienic, agrarian and environmental factors, paying attention to the specific character of both mountain and lagoon areas. Over many centuries new country areas were created, 2/5 of them located below sea level, which can be cultivated due to complex systems of canalization and water pumping. Both the State and landowners invested capital in a project that was not only meant to sustain private interest but that also met public needs. Since 1882 (when the Baccarini law was passed) the subject of the 'sanitary reclamation' began to be discussed in Italy. This concerned 1/16 of the total surface of the country, 400,000 hectares of which in Veneto, where malaria was directly or indirectly responsible for the death of thousands of people. New livelihoods substituted those of the past: some economies based, for instance, on the harvesting of the marshes' products or on the common use of marginal lands disappeared. The recent process of industrialization in Veneto, often carried out with little consideration for the environment, has eventually opened up a new chapter in the history of the countryside of this region, that of environmental and landscape enhancement.

  14. The first Finnish malariologist, Johan Haartman, and the discussion about malaria in 18th century Turku, Finland.

    PubMed

    Hulden, Lena

    2011-01-01

    After the Great Northern War in 1721, Sweden ceased to be an important military power. Instead, the kingdom concentrated on developing science. Swedish research got international fame with names as Carolus Linnaeus, Pehr Wargentin and Anders Celsius. Medical research remained limited and malaria was common especially in the coastal area and along the shores of the big lakes.Already in the beginning of the 18th century Swedish physicians recommended Peruvian bark as medication and they also emphasized that bleeding or blood-letting a malaria patient was harmful. Although malaria was a common disease in the kingdom, the situation was worst in the SW-part of Finland which consisted of the town of Turku and a large archipelago in the Baltic. The farmers had no opportunity to get modern healthcare until Johan Haartman was appointed district physician in 1754. To improve the situation he wrote a medical handbook intended for both the farmers and for persons of rank. Haartman's work was first published 1759 and he discussed all the different cures and medications. His aim was to recommend the best ones and warn against the harmful. His first choice was Peruvian bark, but he knew that the farmers could not afford it. Haartman was appointed professor in medicine at the Royal Academy of Turku in 1765. The malaria situation in Finland grew worse in the 1770's and Haartman analysed the situation. He found the connection between the warm summers and the spring epidemics next year.In a later thesis, Haartman analysed the late summer/early autumn malaria epidemics in the archipelago. Althouh Haartman did not know the connection between malaria and the vector, he gave astute advice and encouraged the farmers to build their cottages in windy places away from the shallow bays in which the Anopheles females hatched. Haartman died in 1788. After his death malaria research in Turku declined. His medical handbook would not be replaced until 1844. PMID:21324104

  15. The first Finnish malariologist, Johan Haartman, and the discussion about malaria in 18th century Turku, Finland

    PubMed Central

    2011-01-01

    After the Great Northern War in 1721, Sweden ceased to be an important military power. Instead, the kingdom concentrated on developing science. Swedish research got international fame with names as Carolus Linnaeus, Pehr Wargentin and Anders Celsius. Medical research remained limited and malaria was common especially in the coastal area and along the shores of the big lakes. Already in the beginning of the 18th century Swedish physicians recommended Peruvian bark as medication and they also emphasized that bleeding or blood-letting a malaria patient was harmful. Although malaria was a common disease in the kingdom, the situation was worst in the SW-part of Finland which consisted of the town of Turku and a large archipelago in the Baltic. The farmers had no opportunity to get modern healthcare until Johan Haartman was appointed district physician in 1754. To improve the situation he wrote a medical handbook intended for both the farmers and for persons of rank. Haartman's work was first published 1759 and he discussed all the different cures and medications. His aim was to recommend the best ones and warn against the harmful. His first choice was Peruvian bark, but he knew that the farmers could not afford it. Haartman was appointed professor in medicine at the Royal Academy of Turku in 1765. The malaria situation in Finland grew worse in the 1770's and Haartman analysed the situation. He found the connection between the warm summers and the spring epidemics next year. In a later thesis, Haartman analysed the late summer/early autumn malaria epidemics in the archipelago. Althouh Haartman did not know the connection between malaria and the vector, he gave astute advice and encouraged the farmers to build their cottages in windy places away from the shallow bays in which the Anopheles females hatched. Haartman died in 1788. After his death malaria research in Turku declined. His medical handbook would not be replaced until 1844. PMID:21324104

  16. Women's translations of scientific texts in the 18th century: a case study of Marie-Anne Lavoisier.

    PubMed

    Kawashima, Keiko

    2011-01-01

    In the 18th century, many outstanding translations of scientific texts were done by women. These women were important mediators of science. However, I would like to raise the issue that the 'selection,' which is the process by which intellectual women chose to conduct translation works, and those 'selections' made by male translators, would not be made at the same level. For example, Émilie du Châtelet (1706-1749), the only French translator of Newton's "Principia," admitted her role as participating in important work, but, still, she was not perfectly satisfied with the position. For du Châtelet, the role as a translator was only an option under the current conditions that a female was denied the right to be a creator by society. In the case of Marie-Anne Lavoisier (1743-1794), like du Châtelet, we find an acute feeling in her mind that translation was not the work of creators. Because of her respect toward creative geniuses and her knowledge about the practical situation and concrete results of scientific studies, the translation works done by Marie-Anne Lavoisier were excellent. At the same time, the source of this excellence appears paradoxical at a glance: this excellence of translation was related closely with her low self-estimation in the field of science. Hence, we should not forget the gender problem that is behind such translations of scientific works done by women in that era. Such a possibility was a ray of light that was grasped by females, the sign of a gender that was eliminated from the center of scientific study due to social systems and norms and one of the few valuable opportunities to let people know of her own existence in the field of science. PMID:22606747

  17. The ``System of Chymists'' and the ``Newtonian dream'' in Greek-speaking Communities in the 17th-18th Centuries

    NASA Astrophysics Data System (ADS)

    Bokaris, Efthymios P.; Koutalis, Vangelis

    2008-06-01

    The acceptance of new chemical ideas, before the Chemical Revolution of Lavoisier, in Greek-speaking communities in the 17th and 18th centuries did not create a discourse of chemical philosophy, as it did in Europe, but rather a “philosophy” of chemistry as it was formed through the evolution of didactic traditions of Chemistry. This “philosophical” chemistry was not based on the existence of any academic institutions, it was focused on the ontology of principles and forces governing the analysis/synthesis of matter and formulated two didactic traditions. The one, named “the system of chymists”, close to the Boylean/Cartesian tradition, accepted, contrary to Aristotelianism, the five “chymical” principles and also the analytical ideal, but the “chymical” principles were not under a conceptual and experimental investigation, as they were in Europe. Also, a crucial issue for this tradition remained the “mechanical” principles which were under the influence of the metaphysical nature of the Aristotelian principles. The other, close to the Boylean/Newtonian tradition, was the integrated presentation of the Newtonian “dream”, which maintained a discursive attitude with reference to the “chemical attractions”-“chemical affinities” and actualised the mathematical atomism of Boscovich, according to which the elementary texture of matter could be causally explained within this complex architecture of mathematical “ punkta”. In this tradition also coexisted, in a discursive synthesis, the “chemical element” of Lavoisier and the arguments of the new theory and its opposition to the phlogiston theory, but the “chemical affinities” were under the realm of the “physical element” as “metaphysical point”.

  18. Marble weathering and air pollution in Philadelphia

    NASA Astrophysics Data System (ADS)

    Feddema, J. J.; Meierding, T. C.

    Maps of damage to marble tombstones in the urban region of Philadelphia demonstrate a close spatial correspondence with airborne pollutant concentrations. Mean recession rates on upper tombstone faces are an order of magnitude greater (3.5 mm (100a) -1) in the center of the city than they are 20 km away in the suburbs and countryside (< 0.5 mm (100a) -1). Not only are more pollutants emitted in the city, but they are also concentrated in the city center by centripetal air movement into the urban heat island. Gaseous SO 2 appears to be the most damaging pollutant, as is shown by the presence of gypsum in urban stones. Although rainfall is important in removing sulfate reaction products, anthropogenically-induced acid rain has only a minor role in marble deterioration. High urban SO 2 concentrations cause sufficient gypsum accumulation within the stones to exfoliate the durable surface layer. Old photos of tombstones in central Philadelphia cemeteries show that exfoliation greatly accelerated between 1930 and 1960, concurrent with increases in SO 2 levels. Recent improvements in air quality are likely to have slowed stone deterioration.

  19. 44. Storehouse of Philadelphia Signal Depot, U.S. Army Corps of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. Storehouse of Philadelphia Signal Depot, U.S. Army Corps of Engineers, War Department (1942) - Atwater Kent Manufacturing Company, North Plant, 5000 Wissahickon Avenue, Philadelphia, Philadelphia County, PA

  20. Strategies for Talent Management: Greater Philadelphia Companies in Action

    ERIC Educational Resources Information Center

    Council for Adult and Experiential Learning (NJ1), 2008

    2008-01-01

    Human capital is one of the critical issues that impacts the Greater Philadelphia region's ability to grow and prosper. The CEO Council for Growth (CEO Council) is committed to ensuring a steady and talented supply of quality workers for this region. "Strategies for Talent Management: Greater Philadelphia Companies in Action" provides insights…

  1. Philadelphia's Renaissance Schools: Start up and Early Implementation. Executive Summary

    ERIC Educational Resources Information Center

    Research for Action, 2011

    2011-01-01

    In April 2009, Superintendent Arlene Ackerman announced her reform plan for the School District of Philadelphia (the District)--"Imagine 2014". Among other major initiatives, "Imagine 2014" laid the groundwork for Philadelphia's Renaissance Schools Initiative. The Renaissance Initiative, set to enter its second year in 2011-12, is an effort to…

  2. Going Small: Progress & Challenges of Philadelphia's Small High Schools

    ERIC Educational Resources Information Center

    Hartmann, Tracey; Reumann-Moore, Rebecca; Evans, Shani Adia; Haxton, Clarisse; Maluk, Holly; Neild, Ruth Curran

    2009-01-01

    Between 2003 and 2007, and without significant outside funding, the School District of Philadelphia created 25 new small high schools. This study, begun by Research for Action in 2006, follows the start-up and early implementation of these small high schools in Philadelphia. The study found that parents and students are interested in small high…

  3. A Trip to Historic Philadelphia on the Web.

    ERIC Educational Resources Information Center

    Wilson, Elizabeth K.

    1997-01-01

    Describes an electronic field trip to colonial Philadelphia (Pennsylvania). The historic locale has generated enough websites (Philadelphia Historic District, Betsy Ross homepage, and the Franklin Institute Science Museum) for students to take a virtual tour of the colonial capital. Suggests structuring the activity as a know-want-learn (KWL)…

  4. South Philadelphia Passive Sampler Method project communication sheet

    EPA Science Inventory

    The Environmental Protection Agency, Office of Research and Development (EPA ORD), EPA Region 3, and the City of Philadelphia Air Measurements Services (AMS) are collaborating on research project in South Philadelphia starting in the spring of 2013. This project investigates how...

  5. Philadelphia School District Deconstruction--A Case Requiring Consideration

    ERIC Educational Resources Information Center

    Lytle, James H.

    2013-01-01

    This article presents the author's views about the school district deconstruction in Philadelphia, Pennsylvania. He discusses his 30-year experience as a principal and central office administrator with the School District of Philadelphia and his involvement in the efforts to lead urban school reform in the country. He also describes the…

  6. For-Profit Writes Mandatory Courses for Philadelphia High Schools

    ERIC Educational Resources Information Center

    Olson, Lynn

    2005-01-01

    This article reports how Kaplan K12 Learning Services Group, a division of Kaplan Inc., has developed a new, standardized college-preparatory curriculum for the Philadelphia school district. The curriculum, which made its debut in the Philadelphia district in 2005, was a critical element in the district leadership's plan to improve secondary…

  7. The Classical Greek Program in the School District of Philadelphia.

    ERIC Educational Resources Information Center

    Masciantonio, Rudolph

    Classical Greek is taught as an elective to over 200 students in seven secondary schools of the School District of Philadelphia. In the past decade the restoration of Greek studies to the classical curriculum was called for, and in 1968 a Greek Curriculum Committee was established in Philadelphia to develop a program and instructional materials.…

  8. A Multi-Analytical Approach for the Evaluation of the Efficiency of the Conservation-Restoration Treatment of Moroccan Historical Manuscripts Dating to the 16th, 17th, and 18th Centuries.

    PubMed

    Hajji, Latifa; Boukir, Abdellatif; Assouik, Jamal; Kerbal, Abdelali; Kajjout, Mohamed; Doumenq, Pierre; De Carvalho, Maria Luisa

    2015-08-01

    The most critical steps during the conservation-restoration treatment applied in Moroccan libraries are the deacidification using immersion in a saturated aqueous calcium hydroxide (Ca(OH)2) solution and the consolidation of degraded manuscripts using Japanese paper. The present study aims to assess the efficiency of this restoration method using a multi-analytical approach. For this purpose, three ancient Arabic Moroccan manuscript papers dating back to the 16th, 17th, and 18th centuries were investigated to characterize the paper support and make a comparative study between pre-restoration and post-restoration states. Three structural and molecular characterization techniques including solid-state nuclear magnetic resonance spectroscopy on (13)C with cross-polarization and magic-angle spinning nuclear magnetic resonance ((13)C CP-MAS NMR), attenuated total reflectance Fourier transform infrared spectroscopy (ATR FT-IR), and X-ray diffraction (XRD) were used to elucidate the cellulose main features, to identify the inorganic composition of the papers, and to study the crystallinity of the samples. Inductively coupled plasma atomic emission spectrometry (ICP-AES) allowed us to obtain a qualitative and quantitative characterization of the mineral fillers used in the manufacturing of the papers. Scanning electron microscopy coupled to energy dispersive spectrometry (SEM-EDS) ascertained the state of conservation of the different papers and helped us to study the elemental composition of the samples. After restoration, it was shown that the deacidification improved the stability of papers by providing an important alkaline buffer, as demonstrated using FT-IR and energy dispersive spectrometry (EDS) results. However, XRD and ICP-AES did not confirm the pertinence of the treatment for all samples because of the unequal distribution of Ca on the paper surface during the restoration. The consolidation process was studied using SEM analysis; its effectiveness in restoring

  9. Spatial trends in S and Cl in ash leachates of the May 18th, 1980 eruption of Mt. St Helens

    NASA Astrophysics Data System (ADS)

    Ayris, Paul M.; Delmelle, Pierre; Durant, Adam J.; Damby, David E.; Maters, Elena C.

    2014-05-01

    It has long been known that surficial deposits of salts and acids on volcanic ash particles derive from interactions of ash with sulphur and halide species within the eruption plume and volcanic cloud. These compounds are mobilised as ash particles are wetted, and beneficial or detrimental environmental and health impacts may be induced where the most concentrated solutions are produced. However, limited mechanistic understanding of gas-ash interactions currently precludes prediction of the spatial distribution or variation in leachate chemistry and concentration following an eruption. Sampling and leachate analysis of freshly-fallen ash therefore offers the sole method by which such variations can be observed. Previous ash leachate studies often involve a limited number of ash samples, and utilise a 'one-dimensional' analysis that considers variation in terms of absolute distance from the source volcano. Here, we demonstrate that extensive sampling and a 'two-dimensional' analysis can uncover more complex spatial trends. We compiled over 358 leachate compositions from the May 18th 1980 eruption of Mt. St. Helens. Of the water-extracted leachates, only 95 compositions from ash sampled at 45 localities between 35 and 1129 km from the volcano are sufficiently documented to be retrospectively comparable. To consider the effects of intra-deposit variability, we calculated average concentrations of leachate data within 11×22 km grid cells across the region, and defined a data quality parameter to reflect confidence in the derived values. To investigate any dependence of leachate composition on the grain size distribution, we generated an interpolated map of geometric specific surface area variation across the deposit, normalising ash leachate data to the calculated specific surface area at the corresponding sampling location. The data treatment identifies S and Cl enrichments in proximal blast deposits; relatively constant Cl concentrations across the ashfall deposits

  10. Neuroimaging of the Philadelphia Neurodevelopmental Cohort

    PubMed Central

    Satterthwaite, Theodore D.; Elliott, Mark A.; Ruparel, Kosha; Loughead, James; Prabhakaran, Karthik; Calkins, Monica E.; Hopson, Ryan; Jackson, Chad; Keefe, Jack; Riley, Marisa; Mensh, Frank D.; Sleiman, Patrick; Verma, Ragini; Davatzikos, Christos; Hakonarson, Hakon; Gur, Ruben C.; Gur, Raquel E.

    2013-01-01

    The Philadelphia Neurodevelopmental Cohort (PNC) is a large-scale, NIMH funded initiative to understand how brain maturation mediates cognitive development and vulnerability to psychiatric illness, and understand how genetics impacts this process. As part of this study, 1,445 adolescents ages 8–21 at enrollment underwent multimodal neuroimaging. Here, we highlight the conceptual basis for the effort, the study design, and measures available in the dataset. We focus on neuroimaging measures obtained, including T1-weighted structural neuroimaging, diffusion tensor imaging, perfusion neuroimaging using arterial spin labeling, functional imaging tasks of working memory and emotion identification, and resting state imaging of functional connectivity. Furthermore, we provide characteristics regarding the final sample acquired. Finally, we describe mechanisms in place for data sharing that will allow the PNC to become a freely available public resource to advance our understanding of normal and pathological brain development. PMID:23921101

  11. Marylanders defeat Philadelphia: yellow fever updated.

    PubMed Central

    Woodward, T. E.; Beisel, W. R.; Faulkner, R. D.

    1976-01-01

    Those strategic points which influence this amateur historian to declare a victory for Baltimore and Maryland over Philadelphia are: I. Based upon clinical and epidemiological data, two Marylanders, Potter and Davidge, were among the first to contest Rush and his contagion theory; they told him so and published their views. To prove this point, Potter went to the extreme of inoculating himself with presumedly infected material. Stubbins Ffirth, a young University of Pennsylvania medical student, did the same four years later. To Rush's credit was ultimate abandonment of his originally held views. II. John Crawford, of Baltimore, although not the originator of the insect concept of transmission of infectious agents, published his concepts in 1811. III. Henry Rose Carter, a Maryland graduate, clearly delineated, in 1898, that after identification of an index case of yellow fever an extrinsic incubation period was necessary before the evolution of secondary cases. IV. James Carroll, another University of Maryland graduate, who worked as Deputy under Walter Reed with Lazear and Agramonte, helped prove Finlay's original concept that the Aedes aegypti mosquito was the natural vector of yellow fever. Carroll himself was the first experimentally induced case. V. Studies in primates provide new approaches for management of yellow fever. Nutritional support and treatment with specific anti-viral agents may be useful for therapy of human yellow fever. Maryland members of the Climatological are mindful of Philadelphia's rich medical heritage and of the many battles won in the City of Brotherly Love. Physicians in colonial and early America experienced The best and worst of times, theirs was an age of foolishness and belief, of incredulity and light, of darkness, despair and hope. This tale of two cities ends in peace. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 10 Fig. 11 PMID:822563

  12. [Medicine and religion in Spanish anti-superstition discourse of the 16th to 18th centuries: a battle for hegemony].

    PubMed

    Campagne, F A

    2000-01-01

    The object of this research is the study of the different kinds of relationships between medicine and religion that appear in the Spanish anti-superstition discourse from the 16th to the 18th century. Despite the relationship of alliance and collaboration between the two professional groups proposed by the Spanish theologians in their essays, situations of conflict and mutual distrust could also arise. The professional physician could be an ally of the Christian priest but also a dangerous rival. PMID:11640189

  13. 18th Workshop on Crystalline Silicon Solar Cells and Modules: Materials and Processes; Workshop Proceedings, 3-6 August 2008, Vail, Colorado

    SciTech Connect

    Sopori, B. L.

    2008-09-01

    The National Center for Photovoltaics sponsored the 18th Workshop on Crystalline Silicon Solar Cells & Modules: Materials and Processes, held in Vail, CO, August 3-6, 2008. This meeting provided a forum for an informal exchange of technical and scientific information between international researchers in the photovoltaic and relevant non-photovoltaic fields. The theme of this year's meeting was 'New Directions for Rapidly Growing Silicon Technologies.'

  14. 10. Photographic copy of original drawings (originals at Amtrack, Philadelphia, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photographic copy of original drawings (originals at Amtrack, Philadelphia, Pennsylvania) PLANS FOR FLOORBEAMS, SWAYS AND RAIL POSTS - Water Street Bridge, US Route 1 spanning Metro-North Commuter Railroad, New Haven, New Haven County, CT

  15. 11. Photographic copy of original drawings (originals at Amtrack, Philadelphia, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photographic copy of original drawings (originals at Amtrack, Philadelphia, Pennsylvania) END POST AND CHORDS - Water Street Bridge, US Route 1 spanning Metro-North Commuter Railroad, New Haven, New Haven County, CT

  16. 5.9 Mw, 18th June 2010 earthquake and fault segment linkage at Andaman - A study based on macroseismic survey, GPS geodesy and Coulomb stress changes

    NASA Astrophysics Data System (ADS)

    Som, S. K.; Jana, Prasun; Mohapatra, S. R.; Nayak, S. K.; Saha, Ashim Kumar

    2013-05-01

    18th June, 2010 5.9 Mw earthquake at North Andaman triggered along NW-SE pre-existing fault with reverse fault mechanism. Macroseismic survey and GPS geodesy reveal maximum damages following NE-SW trend due to normal fault mechanism. Coulomb stress modeling for post- and inter-seismic earthquakes after the 2004 mega-earthquake show different stages of fault segment linkage at North Andaman. The present earthquake has been explained as co-shock due to asiesmic soft linkage of fault propagation.

  17. Energy spectrum and arrival direction of primary cosmic rays of energy above 10 to the 18th power eV

    NASA Technical Reports Server (NTRS)

    Nagano, M.; Honda, M.; Mori, M.; Teshima, M.; Hayashida, N.; He, C. X.; Ishikawa, F.; Kamata, K.; Matsubara, Y.; Ohoka, H.

    1985-01-01

    The observation of ultra high energy cosmic rays with 20 sq km array has started at Akeno. The preliminary results on energy spectrum and arrival direction of energies above 10 to the 18th eV are prsented with data accumulated for four years with the 1 sq km array, for two years with the 4 sq km array and for a half year with the new array. The energy spectrum is consistent with the previous experiments showing the flattening above 10 to the 18.5 eV.

  18. Flood hazard and a rapidly growing capital in the floodplain: Social response on major 18th-century Danube floods in Pest (East-Budapest)

    NASA Astrophysics Data System (ADS)

    Kiss, Andrea

    2014-05-01

    Due to its floodplain location, Pest was especially prone to damages caused by great flood events. Before water regulation works, the greatest flood events, and the highest rate of destruction occurred during ice jam floods. Whereas in the first half of the 18th century Pest is restricted to the medieval downtown located on a higher terrain (Danube terrace), from the mid 18th century onwards the rapidly growing population established suburbs around the downtown in the lower-lying flood plain. Thus, while in the first half of the century floods were more dangerous for the harvest in the agricultural lands, in the second half of the century at the same place suburbs, urban areas with thousands of inhabitants were prone to the same danger. In the first half of the century at least three particularly large flood events, in 1712, 1732 and 1744, caused increasing problems in the close vicinity of the town (and its lands), the second half of the century - as part of a climatic anomaly (Maldá) famous of its weather extremes - was characterised by two extreme (in 1775 and 1799), at least two larger (1789 and 1795) and some more, medium-sized ice jam floods. While in terms of damaged houses the loss was only some dozens in the early part of the century, several hundreds of houses - actually, complete suburbs were erased by floods in 1775 and 1799. In the poster presentation a series of known damaging 18th-century floods, occurred at Pest, is presented, the short-term impacts (e.g. damages), and medium-, long-term administrative responses as well as related long-term landscape changes influenced by floods and flood protection are discussed. Another important aim of the poster is to present the main reasons why in the 18th century these great ice jam floods caused much greater damages (e.g. percentage of collapsed houses in suburbs) in Pest protected by dams than, for example, in the Buda suburbs with no dams, partly also located in high flood-risk areas, in the immediate

  19. ED, heal thyself.

    PubMed

    Becker, Nora V; Friedman, Ari B

    2014-02-01

    Emergency department (ED) wait times have continued to worsen despite receiving considerable attention for more than 2 decades and despite the availability of a variety of methods to restructure care in a more streamlined fashion. This article offers an economic framework that abstracts away from the details of operations research to understand the fundamental disincentives to improving wait times. Hospitals that reduce wait times are financially penalized if they must provide more uncompensated care as a result. Pending changes under the Patient Protection and Affordable Care Act are considered. We find that the likely effect of the Patient Protection and Affordable Care Act's insurance expansion is to reduce this penalty for improving ED wait times. Consequently, mandating adoption of solutions to ED crowding may be unnecessary and counterproductive. If the insurance expansion is insufficient to fully solve the problem, the hospital value-based purchasing initiative should adopt wait times as a goal in its next iteration. PMID:24332901

  20. PREFACE: EDS2010 Preface

    NASA Astrophysics Data System (ADS)

    Heggie, Malcolm I.

    2011-03-01

    The biennial international conference on Extended Defects in Semiconductors started in 1978 with a meeting in Hünfeld, Germany. Subsequent meetings rotated between Poland, France, Great Britain, Germany, Russia and Italy, culminating in EDS2004 in Chernogolovka, EDS2006 in Halle and EDS2008 in Poitiers. EDS2010 was held at the University of Sussex at Brighton, UK from September 19th to 24th. An extension of the tabulation of this history, which first appeared on the EDS2006 website, is given in the attached PDF. It is with sadness that we note one of the founders of the series, Prof. Dr Helmut Alexander, passed away on 3 December 2009 and we were proud to dedicate EDS2010 to his memory. It has become a tradition to make an award in his name, and this year it was made to Ivan Isacov for his poster "Electrical levels of dislocation networks in p- and n-type silicon". A short and warm celebration of Prof. Dr Alexander's life by his friends and colleagues, Prof. Drs Helmut Gottschalk, Eicke Weber and Wolfgang Schröter, is included in this volume. The conference was a forum for the state-of-the-art of investigation and modelling of extended defects in semiconductors. Scientists from universities, research institutes and industry made contributions to a deeper understanding of extended defects, their interaction with point defects and their role in the development of semiconductor technology. The remit of the conference included extended defects, nanostructures, nanoparticles, quantum dots and interfaces within semiconducting materials ranging from narrow to wide band gaps, including graphene-derived materials and diamond. Scientific interests range from defect geometry, electronic structure, dynamics, spectroscopy, microscopy, reactions and chemistry to introduction mechanisms, such as implantation and strained layers and the operation of devices such as integrated circuits, heterostructures, and solar cells. The organisers were confronted with a long period between

  1. Closing the Teacher Quality Gap in Philadelphia: New Hope and Old Hurdles. The Third Study of Teacher Quality in Philadelphia. A Report from "Learning from Philadelphia's School Reform"

    ERIC Educational Resources Information Center

    Useem, Elizabeth; Offenberg, Robert; Farley, Elizabeth

    2007-01-01

    This study of teacher staffing issues in the School District of Philadelphia explores the degree to which the district has succeeded in upgrading teachers' professional credentials, recruiting and retaining them, and equitably distributing experienced and credentialed teachers across all types of schools. Since the passage of "No Child Left…

  2. [Health care in Western Europe in the late 18th century, as reported in Sámuel Cseh-Szombaty's travel journal].

    PubMed

    Rab, Irén

    2015-07-19

    Medical doctors working in Hungary and Transylvania were all trained abroad before the medical faculty of the University of Nagyszombat was founded in 1769. Most Roman Catholic medical students were trained in Vienna and Italy, whereas Protestants in Germany, The Netherlands, and Switzerland. In the 18th century a total of 500 Hungarian medical students studied at universities in Western Europe. Medical students' peregrination did not involve academic training only: whenever they had the possibility, students visited renowned hospitals, university clinics and famous doctors in order to gain experience and medical practice to complete their education. Sámuel Cseh-Szombaty studied in Pest and Göttingen, obtained his medical doctor's diploma in Vienna in 1790, and then spent a year and a half at various medical institutions in Germany, The Netherlands, and England. Cseh-Szombaty's so far unpublished travel journal and alba amicorum provide a wealth of information about the practical knowledge that could be learned during peregrination, characteristics of medical training, patients' treatment, quality of German hospitals of the late 18th century, where the most famous doctors worked. It is an exciting description, how a doctor from Hungary spent his time studying in Western Europe. PMID:26170183

  3. Ankylosing spondylitis or diffuse idiopathic skeletal hyperostosis in royal Egyptian mummies of 18th -20th Dynasties? CT and archaeology studies.

    PubMed

    Saleem, Sahar N; Hawass, Zahi

    2014-12-01

    Objective. To study the computed tomography(CT) images of royal Ancient Egyptian mummies dated to the 18th to early 20th Dynasties for the claimed diagnoses of ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) and to correlate the findings with the archaeology literature.Methods. We studied the CT images of 13 royal Ancient Egyptian mummies (1492–1153 BC) for evidence of AS and DISH and correlated our findings with the archaeology literature.Results. The findings of the CT scans excluded the diagnosis of AS, based on the absence of sacroiliac joint erosions or fusion of the facet joints. Four mummies fulfilled the diagnostic criteria for DISH:Amenhotep III (18th Dynasty), Ramesses II, his son Merenptah, and Ramesses III (19th to early 20th Dynasties).The diagnosis of DISH, a commonly a symptomatic disease of old age, in the 4 pharaohs is in concordance with their longevity and active lifestyles.Conclusion. CT findings excluded the diagnosis of AS in the studied royal Ancient Egyptian mummies and brought into question the antiquity of the disease. The CT features of DISH during this ancient period were similar to those commonly seen in modern populations,and it is likely that they will also be similar in the future.The affection of Ramesses II and his son Merenptah supports familial clustering of DISH. The process of mummification may induce changes in the spine that should be considered during investigations of disease in ancient mummies. PMID:25329920

  4. [Genealogy of the Books of Practica medicinae in Europe before the End of 18th Century: From the Origin to the Disappearance].

    PubMed

    Sakai, Tatsuo

    2015-09-01

    The Practica medicinae represented the books written in Europe before the end of 18th century that dealt with individual deseases. In total, 100 Practica books, written by 95 authors, were collected and divided into four periods from the early 11th to the end of 18th century. The first Practica book was written at the Salernitan medical school on the basis of ancient medical books in the basic style, dealing with regional deseases arranged in "a capite ad calcem" manner, as well as with the fevers. The basic style comprised a majority in the first period and decreased gradually, becoming a minority in the 3rd and 4th periods. Sennert's practica was the largest and it elaborated with precise construction. The additional categories, such as female, children, and surgical deseases increased in the later periods. Those written in non-basic style based on pathogenesis or in alphabetical order also increased in the later periods. The practica books changed slightly and gradually, indicating the essential consistency of the concepts of diseases in these periods. PMID:26775338

  5. Discovery of the Philadelphia chromosome: a personal perspective

    PubMed Central

    Nowell, Peter C.

    2007-01-01

    Almost 50 years ago, David Hungerford and I noticed an abnormally small chromosome in cells from patients with chronic myelogenous leukemia (CML). This article is a personal perspective of the events leading to the discovery of this chromosome, which became known as the Philadelphia chromosome. As technology advanced over subsequent decades, the translocation resulting in the Philadelphia chromosome has been identified, its role in the development of CML has been confirmed, and a therapy directed against the abnormal protein it produces has shown promising results in the treatment of patients with CML. PMID:17671636

  6. Finnish wallpaper pigments in the 18th-19th century: Presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures

    NASA Astrophysics Data System (ADS)

    Castro, Kepa; Knuutinen, Ulla; Vallejuelo, Silvia Fdez-Ortiz de; Irazola, Mireia; Madariaga, Juan Manuel

    2013-04-01

    Several Finish wallpapers from the 18th and 19th century were analysed by using Raman spectroscopy assisted with EDXRF instrumentation, in an attempt of determine the pigments used in their manufacture process as well as of trying to date some of the samples through pigment composition. All pigments present in samples were determined and surprisingly the unusual and strange iron (III) chromate yellow pigment was found. Besides, unusual mixtures were found to obtain fashionable colours, especially in blue and green areas, where more than one blue pigments were mixed with green and yellow pigments. Blue verditer, ultramarine blue, Prussian blue, chrome yellow, calcite, lead white, red and yellow iron oxide, gypsum and carbon black were identified. The presence of the risky and poisonous emerald green must be highlighted. The results were compared with those found in other wallpapers from Spain and France.

  7. Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.

    PubMed

    Castro, Kepa; Knuutinen, Ulla; de Vallejuelo, Silvia Fdez-Ortiz; Irazola, Mireia; Madariaga, Juan Manuel

    2013-04-01

    Several Finish wallpapers from the 18th and 19th century were analysed by using Raman spectroscopy assisted with EDXRF instrumentation, in an attempt of determine the pigments used in their manufacture process as well as of trying to date some of the samples through pigment composition. All pigments present in samples were determined and surprisingly the unusual and strange iron (III) chromate yellow pigment was found. Besides, unusual mixtures were found to obtain fashionable colours, especially in blue and green areas, where more than one blue pigments were mixed with green and yellow pigments. Blue verditer, ultramarine blue, Prussian blue, chrome yellow, calcite, lead white, red and yellow iron oxide, gypsum and carbon black were identified. The presence of the risky and poisonous emerald green must be highlighted. The results were compared with those found in other wallpapers from Spain and France. PMID:23376265

  8. The American College of nuclear physicians 18th annual meeting and scientific sessions DOE day: Substance abuse and nuclear medicine abstracts

    SciTech Connect

    Not Available

    1992-02-01

    Despite the enormous personal and social cost Of substance abuse, there is very little knowledge with respect to the mechanisms by which these drugs produce addiction as well as to the mechanisms of toxicity. Similarly, there is a lack of effective therapeutic intervention to treat the drug abusers. In this respect, nuclear medicine could contribute significantly by helping to gather information using brain imaging techniques about mechanisms of drug addiction which, in turn, could help design better therapeutic interventions, and by helping in the evaluation and diagnosis of organ toxicity from the use of drugs of abuse. This volume contains six short descriptions of presentations made at the 18th Meeting of the American College of Nuclear Physicians -- DOE Day: Substance Abuse and Nuclear Medicine.

  9. [Inadequate burials as an important factor in plague epidemic amongst Serbs in the Habsburg monarchy by the end of the 18th century: a historical analysis].

    PubMed

    Vasin, Goran; Božanić, Snežana; Božić, Milica Kisić

    2014-01-01

    Analysis of the archaic customs of burying the deceased in Srem, primarily amongst Serbs, in the second half of the 18th century is the essential part of the paper that aims at clarifying the consequences of this negative habit onto the spreading of plague epidemic. The Austrian Empire tried to stop and prevent the epidemic with an array of legal norms, but in practice, these orders were often not upheld. Serbian Metropolitans Pavle Nenadović and Stefan Stratimirović insisted on eradicating superstition and retrograde, often uncivilized actions in burial rituals, and they partially succeeded. The example of plague in Irig and the surroundings in 1795-1796 explicitly shows the hazardous effects of the inadequate attitude towards the deceased as one of the factors in spreading the epidemic. Using primary archives, and published sources, with adequate literature, authors depict this complex historical process. PMID:25731012

  10. Forming, transfer and globalization of medical-pharmaceutical knowledge in South East Asian missions (17th to 18th c.) - historical dimensions and modern perspectives.

    PubMed

    Anagnostou, Sabine

    2015-06-01

    From the 17th to the 18th centuries, missionaries in Southeast Asia dedicated themselves to providing and establishing a professional medical-pharmaceutical supply for the local population and therefore explored the genuine Materia medica for easily available and affordable remedies, especially medicinal plants. In characteristic medical-pharmaceutical compendia, which can be classified as missionary pharmacopoeias, they laid down their knowledge to advise others and to guarantee a professional health care. As their knowledge often resulted from an exchange with indigenous communities, these compendia provide essential information about traditional plant uses of Southeast Asian people. Individual missionaries such as the Jesuit Georg Joseph Kamel (1661-1706) not only strove to explore medicinal plants but performed botanical studies and even composed comprehensive herbals. The Jesuit missionaries in particular played roles in both the order's own global network of transfer of medicinal drugs and knowledge about the application, and within the contemporary local and European scientific networks which included, for example, the famous Royal Society of London. The results of their studies were distributed all over the world, were introduced into the practical Materia medica of other regions, and contributed significantly to the academization of knowledge. In our article we will explain the different intentions and methods of exploring, the resulting works and the consequences for the forming of the pharmaceutical and scientific knowledge. Finally, we will show the options which the works of the missionaries can offer for the saving of traditional ethnopharmacological knowledge and for the development of modern phytotherapeutics and pharmaceutical supply. The publication is based on a comprehensive study on the phenomenon of missionary pharmacy which has been published as a book in 2011 (Anagnostou, 2011a) and shows now the potential of historical medical

  11. 78 FR 27025 - Modification of Class B Airspace; Philadelphia, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-09

    ... rulemaking (NPRM) to modify the Philadelphia, PA, Class B airspace area (77 FR 45290, July 31, 2012...: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... aircraft within Class B airspace, reduce controller workload, and reduce the potential for midair...

  12. South Philadelphia Passive Sampler and Sensor Study: Interim Report

    EPA Science Inventory

    Starting in June 2013, the United States Environmental Protection Agency (U.S. EPA) and the City of Philadelphia Air Measurements Services began collaborative research on the use of passive samplers (PSs) and stand-alone air measurement (SAM) systems to improve information on the...

  13. South Philadelphia Passive Sampler and Sensor Study - Interim Report

    EPA Science Inventory

    Starting in the June 2013, the U.S. EPA and the City of Philadelphia Air Measurements Services (AMS) began a collaborative research project to investigate how sensor-based, stand-alone air measurements (SAMs) and passive samplers (PSs) can help improve information on air pollutan...

  14. Short-Form Philadelphia Naming Test: Rationale and Empirical Evaluation

    ERIC Educational Resources Information Center

    Walker, Grant M.; Schwartz, Myrna F.

    2012-01-01

    Purpose: To create two matched short forms of the Philadelphia Naming Test (PNT; Roach, Schwartz, Martin, Grewal, & Brecher, 1996) that yield similar results to the PNT for measuring anomia. Method: In Study 1, archived naming data from 94 individuals with aphasia were used to identify which PNT items should be included in the short forms. The 2…

  15. The Philadelphia School District's Ongoing Financial Crisis

    ERIC Educational Resources Information Center

    Caskey, John; Kuperberg, Mark

    2014-01-01

    This article describes the budget crisis that the School District of Philadelphia has faced for the past few years. Three specific events triggered the 2012 crisis: an abrupt reduction in federal and state funding, the inability of the district to cut many of its costs, and political pressures on the district to spend available revenues in a given…

  16. Gratifications Lost: The 1985 Philadelphia Newspaper Strike and Media Use.

    ERIC Educational Resources Information Center

    Elliott, William R.; Rosenberg, William L.

    A study examined the relationship between newspaper gratifications sought and media use during and after a 1985 strike by unions of two Philadelphia newspapers, and the compensatory media behaviors, if any, people adopted to make up for the loss of their daily newspaper(s). It was hypothesized that during the strike, people would read more…

  17. Lodging Management Career Questionnaire of Greater Philadelphia Area.

    ERIC Educational Resources Information Center

    Bennett, Robert C., Jr.; Wetzel, Susan J.

    A survey was undertaken by Delaware County Community College's (Pennsylvania) Hotel/Restaurant Management program: (1) to provide students with local up-to-date information regarding the lodging industry in the Greater Philadelphia area; and (2) to provide information regarding necessary skills as perceived by the managers for the purpose of…

  18. The Library Company of Philadelphia: Historical Survey, Bibliography, Chronology.

    ERIC Educational Resources Information Center

    Sable, Martin H.

    1987-01-01

    Traces the history of the Library Company of Philadelphia, which was founded by Benjamin Franklin. Early book selection and scope of the collection, subsequent growth and development, and the various directors of the company are described. The bibliography includes publications of the Library Company and publications about the Library Company.…

  19. Identity Performance and Collectivist Leadership in the Philadelphia Student Union

    ERIC Educational Resources Information Center

    Rosen, Sonia M.

    2016-01-01

    Youth organizing work benefits young people in myriad ways, equipping them with the skills and dispositions to organize around the systemic inequities and policy decisions that threaten their communities. The findings from this life histories study in the Philadelphia Student Union (PSU) reveal that the organization's collectivist leadership model…

  20. A Research Brief: "Principals' Hiring of Teachers in Philadelphia"

    ERIC Educational Resources Information Center

    Ramirez, Heidi A.; Schofield, Lynne Steuerle; Black, Melissa

    2008-01-01

    The School District of Philadelphia (SDP), like many other urban school districts, struggles to increase its hiring and retention of experienced and highly qualified teachers in its low-performing/high-need schools. Excluding its charter schools, SDP serves approximately 165,000 students, largely from high-poverty (76%) and minority (85%)…

  1. Faith Partnerships and Public Schools in Philadelphia: Rewards and Perils.

    ERIC Educational Resources Information Center

    Mundell, Leah

    In 1999, Philadelphia (Pennsylvania) school superintendent David Hornbeck introduced educators and religious leaders to his requirement that each public school in the city develop a relationship with a faith partner, a religious institution that could share facilities and resources with the school. Hornbeck saw religious institutions and schools…

  2. Urban School Dropouts: Data Collection and Analysis in Philadelphia.

    ERIC Educational Resources Information Center

    Herron, William P.; Kemp, Edith S.

    In the late 1960's, educators and researchers became concerned with the dropout problem in large urban school districts. In Philadelphia, the Division of Pupil Personnel and Counseling (PPC) is responsible for collection of this data and reports this information to the state. The process has been computerized to cope with the large volume of data.…

  3. 77 FR 47792 - Drawbridge Operation Regulation; Schuylkill River, Philadelphia, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... FR 3316). Public Meeting We do not now plan to hold a public meeting. But you may submit a request... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Schuylkill River... River, mile 6.4 near Christian Street, at Philadelphia, PA. The proposed rule intends to change...

  4. 77 FR 63727 - Drawbridge Operation Regulation; Schuylkill River, Philadelphia, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... Operation Regulation; Schuylkill River, Philadelphia, PA in the FR (77 FR 47792). We received no comments on... FR Federal Register NPRM Notice of Proposed Rulemaking Sec. Section Symbol U.S.C. United States Code... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Schuylkill...

  5. Philadelphia's Renaissance Schools Initiative: 18 Month Interim Report

    ERIC Educational Resources Information Center

    Gold, Eva; Norton, Michael H.; Good, Deborah; Levin, Stephanie

    2012-01-01

    This report presents Year One (2010-11) school level achievement and attendance outcomes and case study findings from fall 2011 that focused on school leadership and instruction. Thirteen schools were included in the first year of Philadelphia's Renaissance Schools Initiative (2010-11). Of these schools: (1) Four K-8 schools were…

  6. Item Response Theory Modeling of the Philadelphia Naming Test

    ERIC Educational Resources Information Center

    Fergadiotis, Gerasimos; Kellough, Stacey; Hula, William D.

    2015-01-01

    Purpose: In this study, we investigated the fit of the Philadelphia Naming Test (PNT; Roach, Schwartz, Martin, Grewal, & Brecher, 1996) to an item-response-theory measurement model, estimated the precision of the resulting scores and item parameters, and provided a theoretical rationale for the interpretation of PNT overall scores by relating…

  7. Transition to High School: School "Choice" & Freshman Year in Philadelphia

    ERIC Educational Resources Information Center

    Gold, Eva; Evans, Shani Adia; Haxton, Clarisse; Maluk, Holly; Mitchell, Cecily; Simon, Elaine; Good, Deborah

    2010-01-01

    The School District of Philadelphia's tiered system of selective, nonselective, and charter high schools, and the process for high school choice, has created real variation in the degree to which high schools can successfully meet the needs of ninth graders. Research has shown that the ninth grade year is critical in determining a student's…

  8. Desegregation of Urban Schools... Is it Possible? The Philadelphia Story.

    ERIC Educational Resources Information Center

    Hanusey, Richard D.

    Philadelphia's voluntary school desegregation plan is designed to offer pupils the opportunity for educational experiences in multicultural, multiracial schools, and to prevent white flight from the public schools. Strategies for achieving desegregation include the creation of magnet schools, voluntary school pairing, the Alternative for Middle…

  9. WorkReady Philadelphia: Preparing Youth for Job Readiness

    ERIC Educational Resources Information Center

    Pawlowski, Brett

    2010-01-01

    One of the great concerns of the business community involves the workforce pipeline: employers want to be sure that new entries into the labor pool, whether from the K-12 or postsecondary systems, are prepared for the jobs that await them. In Philadelphia, business and community leaders have joined forces to give students workplace learning…

  10. Literacy, Place, and Migration in Philadelphia among Ethnic Chinese

    ERIC Educational Resources Information Center

    Rovito, Michael; Masucci, Michele

    2009-01-01

    We introduce the need for scholars interested in literacy, geography, and cultural studies to examine the role of English language literacy in shaping assimilation experiences of recent immigrant groups. We consider a case study of English language self-efficacy among ethnic Chinese immigrants in the Philadelphia metropolitan area to suggest how…

  11. Language and Literacy Development in a Cambodian Community in Philadelphia.

    ERIC Educational Resources Information Center

    Hardman, Joel Carlton

    This study focused on language and literacy learning in a group of Cambodian families in Philadelphia (Pennsylvania) linked locally by an English-as-a-Second-Language (ESL) class, and more broadly by common histories, culture, and language. Over a period of 3 years, the researcher looked at: broad patterns of language and literacy use in this…

  12. Actionable Intelligence about Early Childhood Risks in Philadelphia

    ERIC Educational Resources Information Center

    LeBoeuf, Whitney A.; Barghaus, Katherine; Fantuzzo, John; Coe, Kristen; Brumley, Benjamin

    2016-01-01

    "Early childhood risks" are markers of early childhood experiences that extensive research has shown to be detrimental to later academic and behavioral outcomes. In Philadelphia, evidence indicates that seven early childhood risks tracked by public agencies have negative effects on early school outcomes. These risks include low…

  13. Systemwide Implementation of Project-Based Learning: The Philadelphia Approach

    ERIC Educational Resources Information Center

    Schwalm, Jason; Tylek, Karen Smuck

    2012-01-01

    Citywide implementation of project-based learning highlights the benefits--and the challenges--of promoting exemplary practices across an entire out-of-school time (OST) network. In summer 2009, the City of Philadelphia and its intermediary, the Public Health Management Corporation (PHMC), introduced project-based learning to a network of more…

  14. (Dis)empowerment: The Implementation of Corrective Mathematics in Philadelphia Empowerment Schools

    ERIC Educational Resources Information Center

    Connor, Hannah

    2011-01-01

    The need to improve math education around the country has been well documented, especially in urban school systems like Philadelphia. In Spring 2010, only 56.6% of students in Philadelphia Public schools scored proficient or advanced on the Pennsylvania State Standardized Assessment (PSSA). In Philadelphia Empowerment Schools, the 107 lowest…

  15. Edward (Ed) T. Schneider

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Research Pilot Edward T. Schneider is shown sitting in the cockpit of a McDonnell Douglas F/A-18 Hornet that was used in the High Angle-of-Attack Research Vehicle (HARV) program at the National Aeronautics and Space Administration's Ames - Dryden Flight Research Facility. When the aircraft arrived at the Dryden Facility in 1987, from the US Naval Air Test Center, Patuxent River, Maryland, it consisted of parts in crates. The aircraft crew made an airplane from those parts, and in doing so they took a 'sow's ear' and created a 'silk purse', thus the name on the side of the aircraft. Ed's helmet is from his time in the Navy. The design was taken from the Flag that is flown on the bow of a Navy ship, referred to as the Jack, and is navy blue with the 50 States being represented by the white stars. Ed arrived at the NASA Ames-Dryden Flight Research Facility (later renamed the Dryden Flight Research Center) on July 5, 1982, as a Navy Liaison Officer, becoming a NASA research pilot one year later. Ed was the project pilot for the F-18 High Angle-of-Attack program and later served as a project pilot for the F-15 aeronautical research aircraft, the NASA B-52 launch aircraft, and the SR-71 'Blackbird' aircraft. He served on active duty with the U.S. Navy from 1968 to 1983. Following squadron service he graduated from the U.S. Naval Test Pilot School, Patuxent River, Maryland, in 1973, and then served as an engineering test pilot, and test pilot school instructor at the Naval Air Test Center. Ed has been an active member of the Society of Experimental Test Pilots since 1974. He was made a Fellow of the Society in 1993 and served as its President in 1993/94. In 1996 he was awarded the NASA Exceptional Service Medal and the American Institute of Aeronautics and Astronautics' Chanute Flight Award. He retired as a NASA research pilot in September 2000.

  16. De Renatu Linguarum Antiquarum in Scholis Publicis Philadelphiae (On the Revival of Classical Languages in the Public Schools of Philadelphia)

    ERIC Educational Resources Information Center

    Masciantonio, Rudolph

    1977-01-01

    The enrollment in Latin and Greek classes in the Philadelphia public schools has increased greatly in the last ten years. Courses are offered in elementary as well as secondary schools. An audiolingual approach is used. Available from Universitaet des Saarlandes, Fachbereich 6.2, D-6600 Saarbrueken, West Germany. (Text is in Latin.) (CFM)

  17. Structural and behavioural changes in the short term preventive check in the northwest Balkans in the 18th and 19th centuries.

    PubMed

    Hammel, E A; Galloway, P R

    2000-03-01

    Fertility responded negatively to grain insufficiency (proxied by grain price increases), and mortality responded positively in Croatia-Slavonia-Srem in the 18th and 19th centuries, as in most of Europe. Shifts in the intensity and timing of these responses occurred over time as social and economic structures changed. Shifts in the elasticity of fertility with respect to grain supply inversely mimic and lag changes in the elasticity of mortality. Both appear to be induced by increasing land shortage, the collapse of feudalism, and differences in the patterns of adjustment to post-feudal conditions among former civil and military serfs. Generally, responses are stronger for civil and former civil serfs, who may have been in less favorable economic circumstances than the military. Fertility responses in the year of a price shock come to dominate those in the year following, suggesting a shift from contraception to abortion as economic and social conditions apparently worsened and strategies of control intensified. Analysis of monthly responses supports the conjecture based on the annual responses. The shift to the preventive check and strength of the preventive check in the same year as the price shock is unusual in Europe and beyond. Analysis is based on 25 parishes and employs lagged annual and monthly time series analysis with corrections for autocorrelation, in combination with ethnographic and historical data. PMID:12159002

  18. 18th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer. 30 October-2 November 2003, Bethesda, Maryland, USA.

    PubMed

    Marincola, Francesco M; Wang, Ena; Atkins, Michael B

    2004-01-01

    The 18th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer (iSBTc) was held at the Hyatt Regency, Bethesda, MD, close to the National Institutes of Health (NIH) campus. The meeting was organised on behalf of the society by Neil Berinstein from Aventis Pasteur, Toronto, Canada, Janice P Dutcher from Our Lady of Mercy Medical Center, Bronx, NY and Francesco M Marincola from the NIH, Bethesda, MD. The 2003 meeting included 57 oral presentations and > 100 poster presentations. There were > 800 registrants to the Annual Meeting and the multiple satellite symposia. The iSBTc, formerly the Society of Biological Therapy (SBT), was founded by R Oldham in 1984. Its membership has been rapidly growing of late, with > 500 members at present. The purpose of the iSBTc is to bring together those diverse individuals actively investigating biologic agents and biological response modifiers in the treatment of cancer, including clinicians and basic scientists from industry, government and academia. The President of the Society is Dr Michael B Atkins from Beth Israel Deaconess Medical Center, Boston, MA and the Vice President is Ulrich Keilholz from UKBF, Free University Berlin, Germany. PMID:14680473

  19. Quantitative analysis of human remains from 18(th)-19(th) centuries using X-ray fluorescence techniques: The mysterious high content of mercury in hair.

    PubMed

    Pessanha, Sofia; Carvalho, Marta; Carvalho, Maria Luisa; Dias, António

    2016-01-01

    In this work, we report the unusual concentration of mercury in the hair of an individual buried in the 18th to mid-19th centuries and the comparison with the elemental composition of other remains from the same individual. Two energy dispersive X-ray fluorescence (EDXRF) setups, one with tri-axial geometry and the second one with micro-beam capabilities and a vacuum system, for light elements detection, have been used. Quantitative evaluation of the obtained spectra were made by fundamental parameters and winAXIL program by compare mode method. The levels of Hg in the hair of buried samples presented a concentration over 5% (w/w), a significantly lower presence of this element in the cranium, and no Hg in the remaining organs. Furthermore, there was no evidence of Hg in the burial soil, which has been also analyzed. From this result, we could conclude that the possibility of post-mortem contamination from the burial surroundings is very unlikely. The obtained results are indicative of the apparent use of a mercury-based compound for medical purposes, most likely lice infestation. PMID:26653740

  20. The inquisitorial trial of a cross-dressing lesbian: reactions and responses to female homosexuality in 18th-century portugal.

    PubMed

    Soyer, François

    2014-01-01

    This article analyzes the inquisitorial trial of Maria Duran, a Catalan novice in the Dominican convent of Nossa Senhora do Paraíso in Portugal. Maria Duran was arrested by the Inquisition in 1741 and, after a lengthy trial, condemned in 1744 to a public lashing and exile. She was suspected of having made a pact with the Devil and was accused by many female witnesses of possessing a "secret penis" that she had allegedly used in her amorous relations with fellow nuns and novices. Her voluminous trial dossier offers a rare and fascinating documentary insight into the often extreme reactions that female homosexuality provoked from both men and women in early modern Portugal. Using the evidence offered by the 18th-century trial of Maria Duran, this article highlights female bewilderment when faced with female-on-female sexual violence and the difficulty that men (in this case, churchmen) had coming to terms with the existence of female homosexuality. It also discusses the case in light of the acts/identity debate among historians of the history of sexuality. PMID:25022623

  1. Structural and optical properties of wood and wood finishes studied using optical coherence tomography: application to an 18th century Italian violin.

    PubMed

    Latour, Gaël; Echard, Jean-Philippe; Soulier, Balthazar; Emond, Isabelle; Vaiedelich, Stéphane; Elias, Mady

    2009-11-20

    Optical coherence tomography (OCT) is especially attractive for the study of cultural heritage artifacts because it is noninvasive and nondestructive. We have developed an original full-field time-domain OCT system dedicated to the investigation of varnished and painted artifacts: an interferometric Mirau objective allows one to perform the scan without moving the works of art. The axial and transverse high resolution (respectively, 1.5 and 1 microm) are well adapted to the detection of the investigated structures (pigment grains, wood fibers, etc.). The illumination spectrum is in the visible range (centered at 630 nm, 150 nm wide) to potentially allow us to perform spectroscopic OCT on pigment particles. The examination of wood samples coated with a traditional finish, demonstrates the ability of the system to detect particles, characterize layers thickness, and image the three-dimensional wood structures below the varnishes. OCT has finally been applied to study in situ the coated wood surface of an 18th century Italian violin and provides important information for its conservation treatment. PMID:19935970

  2. Demonstration Assessment of LED Roadway Lighting: Philadelphia, PA

    SciTech Connect

    Royer, Michael P.; Tuenge, Jason R.; Poplawski, Michael E.

    2012-09-01

    For this demonstration assessment, 10 different groups of LED luminaires were installed at three sites in Philadelphia, PA. Each of the three sites represented a different set of conditions, most importantly with regard to the incumbent HPS luminaires, which were nominally 100 W, 150 W, and 250 W. The performance of each product was evaluated based on manufacturer data, illuminance calculations, field measurements of illuminance, and the subjective impressions of both regular and expert observers.

  3. Rebooting the EdD

    ERIC Educational Resources Information Center

    Wergin, Jon F.

    2011-01-01

    In this essay, Jon Wergin reminds readers of the philosophical and historical foundations of the doctor of education (EdD) degree. He argues that the EdD should be based, in large part, on John Dewey's progressive ideals of democratization and Paulo Freire's concepts of emancipatory education. Drawing on theories of reflective practice,…

  4. What Is Ag-Ed?

    ERIC Educational Resources Information Center

    Lindley, Judy

    Ag-Ed is an agricultural education project aimed at upper primary students, held in conjunction with the Toowoomba Show (similar to a county fair) in Queensland, Australia. The program achieves its purpose of helping children understand the impact and relevance that agriculture has on their everyday lives through two components, an Ag-Ed day and a…

  5. "Do Not Turn a Deaf Ear or a Blind Eye on Me, as I Am Your Son": New Conceptions of Childhood and Parenthood in 18th- and 19th-Century Jewish Letter-Writing Manuals

    ERIC Educational Resources Information Center

    Kogman, Tal

    2016-01-01

    This article focuses on the cultural functions of Hebrew letter-writing manuals published in German-speaking countries in the 18th and 19th centuries, aimed at young people. I argue that these books, which were used frequently as textbooks for studying Hebrew writing, conveyed modern ideological values and at the same time corresponded to the…

  6. [Louis XIV's Ginseng: Shaping of Knowledge on an Herbal Medicine in the Late 17th and the Early 18th Century France].

    PubMed

    Lee, Hye-Min

    2016-04-01

    This article aims to investigate the shaping of knowledge and discourse on ginseng, especially among physicians and botanists, since its introduction to France from the 17th century until the early 18th century. In France, knowledge on herbal medicine, including that of ginseng, was shaped under the influence of the modern state's policy and institution: mercantilism and the Académie royale des sciences. The knowledge of herbal medicine developed as an important part of the mercantilist policy supported systematically by the Académie. The East Asian ginseng, renowned as a panacea, was first introduced into France in the 17th century, initially in a roundabout way through transportation and English and Dutch publications of travel tales from various foreign countries. The publication activity was mainly conducted by Thévenot company with the intention to meet the needs of French mercantilism promoted by Colbert. It also implied interests on medicine in order to bolster the people's health. The Thévenot company's activity thus offered vital information on plants and herbs abroad, one of which was ginseng. Furthermore, with Louis XIV's dispatching of the Jesuit missionaries to East Asia, the Frenchmen were able to directly gather information on ginseng. These information became a basis for research of the Académie. In the Académie, founded in 1666 by Colbert, the king's physicians and botanists systematically and collectively studied on exotic plants and medical herbs including ginseng. They were also key figures of the Jardin du Roi. These institutions bore a striking contrast to the faculty of medicine at the University of Paris which has been a center of the traditional Galenic medicine. The research of the Académie on ginseng was greatly advanced, owing much to the reports and samples sent from China and Canada by Jartoux, Sarrazin, and Lapitau. From the early 18th century, the conservative attitude of the University of Paris, which was a stronghold of

  7. Effects of prenatal X-irradiation on the 14th-18th days of gestation on postnatal growth and development in the rat

    SciTech Connect

    Jensh, R.P.; Brent, R.L.

    1988-11-01

    Thirty-nine pregnant adult Wistar strain rats were randomly assigned to one of three exposure groups: 0, 0.75, or 1.50 Gy X-radiation total exposure. Animals were exposed from the 14th to the 18th days of gestation at 0, 0.15, or 0.30 Gy per day. At term, 15 rats were killed and morphologic analyses were completed. Twenty-four rats were allowed to deliver their offspring. On the first day of postnatal life, litters were reduced to a maximum of eight pups per litter, with equal numbers of male and female offspring wherever possible. A total of 187 pups were observed for the age of acquisition of five reflexes (air righting, surface righting, visual placing, negative geotaxis, auditory startle) and the appearance of four physiologic markers (pinna detachment, eye opening, vaginal opening, testes descent). There was significant dose-related weight reduction in term fetuses and offspring throughout the 86-day postnatal period. Postnatal growth rate (g gained/day) was unaffected. Adult offspring brain and gonadal weight and organ weight:body weight ratios were reduced. Using the PAC50 methodology, dose-related alterations occurred in the acquisition of several reflexes. All physiologic markers exhibited a dose-related delay in appearance. These results indicate that fractionated exposure to X-radiation during the fetal period in the rat results in dose-dependent alterations in postnatal growth and physiologic development. These studies are important for our understanding of the long-range effects of prenatal exposure to ionizing radiation late in gestation.

  8. The Problem of Longitude in the 18th Century: Jorge Juan, Antonio de Ulloa and the Expedition of the Paris Academy of Sciences to the Kingdom of Peru

    NASA Astrophysics Data System (ADS)

    Gutiérrez, Manuel Pérez

    2015-05-01

    Jorge Juan and Antonio de Ulloa, naval officers of the Spanish Navy in the Midshipmen's Royal Academy were appointed to take part in one of the most important scientific expeditions of the 18th century. The question of the shape of the Earth, of vital importance for navigation, was solved by the Paris Academy of Sciences by request of Louis XV of France in 1735. The aim was to determine the form of the ellipsoid that Newton had described in the 17th century for any spherical and homogeneous body in rotation about an axis. Two expeditions were prepared for the geodetic measures of meridian arc both in high latitudes (Lapland, Finland) and in the equatorial zone (the Kingdom of Peru); Pierre Louis Maupertuis took charge of the northern expedition whereas the second one was charged to La Condamine, along with Jorge Juan and Antonio de Ulloa. The results obtained by the Spaniards were gathered in a publication: Observaciones astronómicas y físicas hechas en los Reinos del Perú. In it, they dedicate a chapter to the determination of astronomic longitude with the only technology that was providing certain precision at the moment: the simultaneous observation of the same astronomic phenomenon in two different places. Specifically, they explain in detail in Book III: Las Observaciones de la Inmersiones y Emersiones de los satélites de Júpiter, como asimismo de los eclipses de Luna; de las cuales de deduce la Longitud de los Lugares, incluyendo las correcciones a efectuar por la variación de la declinación diaria del Sol.

  9. Dioxin analysis of Philadelphia northwest incinerator. Summary report. Volume 1

    SciTech Connect

    Milner, I.

    1986-01-01

    A study was conducted by US EPA Region 3 to determine the dioxin-related impact of the Philadelphia Northwest Incinerator on public health. Specifically, it was designed to assess quantitatively the risks to public health resulting from emissions into the ambient air of dioxins as well as the potential effect of deposition of dioxins on the soil in the vicinity of the incinerator. Volume 1 is an executive summary of the study findings. Volume 2 contains contractor reports, laboratory analysis results and other documentation.

  10. The Recovery Act is "Lighting Up" the streets of Philadelphia

    SciTech Connect

    Nutter, Michael; Gajewski, Katherine; Russell, Toby; Williams, Doug; Best, DeLain

    2010-01-01

    The Philadelphia Streets Department is converting 58,000 yellow and green traffic signals and will replace approximately 27,000 red LED lights that have come to the end of their useful life. The project will use approximately $3 million in EECBG funds, matched with $3 million in PECO funding, and will save the city approximately $1 million in electric costs each year. For more information on Recovery Act projects funded by the Department of Energy in Pennsylvania: http://www.energy.gov/recovery/pa.htm

  11. The Recovery Act is "Lighting Up" the streets of Philadelphia

    ScienceCinema

    Nutter, Michael; Gajewski, Katherine; Russell, Toby; Williams, Doug; Best, DeLain;

    2013-05-29

    The Philadelphia Streets Department is converting 58,000 yellow and green traffic signals and will replace approximately 27,000 red LED lights that have come to the end of their useful life. The project will use approximately $3 million in EECBG funds, matched with $3 million in PECO funding, and will save the city approximately $1 million in electric costs each year. For more information on Recovery Act projects funded by the Department of Energy in Pennsylvania: http://www.energy.gov/recovery/pa.htm

  12. Establishing a Physics mentoring Program for a Philadelphia Middle School

    NASA Astrophysics Data System (ADS)

    Mlack, J. T.; Wilson, A.; Harris, W.; White, A.; Mehta, S. S.; Ramdass, V.

    2010-03-01

    Our SPS chapter has established a regular physics mentoring program at Independence Charter Middle School located in Philadelphia, PA. Members visit the school on a bi-weekly basis and perform 1-2 hour, inquiry-based lecture demonstrations of physics phenomena that integrate with the science lessons of middle school students. At the end of the school year, a capstone activity in the form of a Rube Goldberg competition among the middle school students was held on the Drexel campus with Drexel faculty and graduate students participating as judges.

  13. Human impacts of hydrometeorological extremes in the Bohemian-Moravian Highlands derived from documentary sources in the 18th-19th centuries

    NASA Astrophysics Data System (ADS)

    Dolák, Lukáš; Brázdil, Rudolf; Valášek, Hubert

    2014-05-01

    The extent of damage caused by hydrometeorological events or extremes (HME) has risen up in the entire world in the last few years. Especially the floods, flash floods, torrential rains and hailstorms are the most typical and one of the most frequent kind of natural disasters in the central Europe. Catastrophes are a part of human history and people were forced to cope with their consequences (e. g. material damage, economical losses, impacts on agriculture and society or losses of human lives). This paper analyses the human impacts of HME in the Bohemian-Moravian Highlands (central part of the Czech Republic) on the basis of documentary sources from the 18th-19th centuries. The paper presents various negative impacts of natural disasters on lives and property and subsequent inconveniences of Czech peasants. The preserved archival documents of estates or domains became the primary sources of data (e. g. taxation reliefs, damaged records, reports of afflicted farmers, administrative correspondence etc.). Particularly taxation reliefs relate to taxation system in the Czech lands during the 17th-19th centuries allowing to farmers to ask for tax alleviation when their crops were significantly damaged by any HME. These archival documents are a highly valuable source for the study of human impacts of natural disasters. Devastating consequences of these extremes affected individual farmers much more than the aristocracy. Floods caused inundations of farmer's fields, meadows, houses and farm buildings, washed away the arable land with crops, caused losses of cattle, clogged the land with gravel and mud and destroyed roads, bridges or agricultural equipment. Afflicted fields became worthless and it took them many years to become became fertile again. Crop was also damaged by hailstorms, droughts or late/early frosts. All these events led to lack of food and seeds in the following year and it meant the decrease of living standard, misery and poverty of farmers. Acquired

  14. Effects of slope on the formation of dunes in dilute, turbulent pyroclastic currents: May 18th, 1980 Mt. St. Helens eruption

    NASA Astrophysics Data System (ADS)

    Bendana, Sylvana; Brand, Brittany D.; Self, Stephen

    2014-05-01

    The flanks of Mt St Helens volcano (MSH) are draped with thin, cross-stratified and stratified pyroclastic density current (PDC) deposits. These are known as the proximal bedded deposits produced during the May 18th, 1980 eruption of MSH. While the concentrated portions of the afternoon PDCs followed deep topographic drainages down the steep flanks of the volcano, the dilute overriding cloud partially decoupled to develop fully dilute, turbulent PDCs on the flanks of the volcano (Beeson, D.L. 1988. Proximal Flank Facies of the May 18, 1980 Ignimbrite: Mt. St. Helens, Washington.). The deposits along the flank thus vary greatly from those found in the pumice plain, which are generally thick, massive, poorly-sorted, block-rich deposits associated with the more concentrated portions of the flow (Brand et al, accepted. Dynamics of pyroclastic density currents: Conditions that promote substrate erosion and self-channelization - Mount St Helens, Washington (USA). JVGR). We explore the influence of topography on the formation of these dilute currents and influence of slope on the currents transport and depositional mechanisms. The deposits on steeper slopes (>15°) are fines depleted relative to the proximal bedded deposits on shallower slopes (<15°). Bedform amplitude and wavelength increase with increasing slope, as does the occurrence of regressive dunes. Increasing slope causes an increase in flow velocity and thus an increase in flow turbulence. The fines depleted deposits suggest that fine ash elutriation is more efficient in flows with stronger turbulence. The longer wavelength and amplitudes suggest that bedform morphology is directly related to flow velocity, an important finding since the controls on bedform wavelength and amplitude in density stratified flows remains poorly constrained. The occurrence of regressive dunes, often interpreted as high flow-regime bedforms, on steeper slopes relative to progressive dunes on shallower slopes further attests to the

  15. Paleoclimate Reconstruction during the 17th to 18th Century Using Fossil Coral Tsunami Boulders from Ishigaki Island, the Ryukyus, Japan

    NASA Astrophysics Data System (ADS)

    Tsuzuki, K.; Yokoyama, Y.; Seki, A.; Kawakubo, Y.; Araoka, D.; Suzuki, A.

    2014-12-01

    Resolution Inductively Coupled Plasma Mass Spectrometry) to reconstruct paleo SST during LIA (Kawakubo et al., 2014). LA-HR-ICPMS enables us to measure the long coral core rapidly. Our result shows SST variation in 17th-18th century in this area and SST declined in around 1700. This result reveals the response of Little Ice Age in the northwestern Pacific.

  16. Racial Disparities In Geographic Access To Primary Care In Philadelphia.

    PubMed

    Brown, Elizabeth J; Polsky, Daniel; Barbu, Corentin M; Seymour, Jane W; Grande, David

    2016-08-01

    Primary care is often thought of as the gateway to improved health outcomes and can lead to more efficient use of health care resources. Because of primary care's cardinal importance, adequate access is an important health policy priority. In densely populated urban areas, spatial access to primary care providers across neighborhoods is poorly understood. We examined spatial variation in primary care access in Philadelphia, Pennsylvania. We calculated ratios of adults per primary care provider for each census tract and included buffer zones based on prespecified drive times around each tract. We found that the average ratio was 1,073; the supply of primary care providers varied widely across census tracts, ranging from 105 to 10,321. We identified six areas of Philadelphia that have much lower spatial accessibility to primary care relative to the rest of the city. After adjustment for sociodemographic and insurance characteristics, the odds of being in a low-access area were twenty-eight times greater for census tracts with a high proportion of African Americans than in tracts with a low proportion of African Americans. PMID:27503960

  17. Urban ecosystem services and decision making for a green Philadelphia

    USGS Publications Warehouse

    Hogan, Dianna M.; Shapiro, Carl D.; Karp, David N.; Wachter, Susan M.

    2014-01-01

    Traditional approaches to urban development often do not account for, or recognize, the role of ecosystem services and the benefits these services provide to the health and well-being of city residents. Without such accounting, urban ecosystem services are likely to be degraded over time, with negative consequences for the sustainability of cities and the well-being of their residents (Millennium Ecosystem Assessment, 2005; Hirsch, 2008). On May 23, 2013, the Spatial Integration Laboratory for Urban Systems (SILUS), a collaboration between the U.S. Geological Survey (USGS) Science and Decisions Center and the Wharton GIS Lab, convened a one-day symposium—Urban Ecosystem Services and Decision Making: A Green Philadelphia—at the University of Pennsylvania in Philadelphia, Pennsylvania, to examine the role of green infrastructure in the environmental, economic, and social well-being of cities. Cosponsored by the USGS and the Penn Institute for Urban Research (Penn IUR), the symposium brought together policymakers, practitioners, and researchers from a range of disciplines to advance a research agenda on the use of science in public decision making to inform investment in green infrastructure and ecosystem services in urban areas. The city of Philadelphia has recently implemented a program designed to sustain urban ecosystem services and advance the use of green infrastructure. In 2009, the Philadelphia Mayor’s Office of Sustainability launched its Greenworks plan, establishing a citywide sustainability strategy. Major contributions towards its goals are being implemented in coordination with the Philadelphia Water Department (PWD). The Green City, Clean Waters initiative, the city’s nationally recognized stormwater management plan, was signed into action with the U.S. Environmental Protection Agency (EPA) in April 2012. The plan outlines a 25-year strategy to use green infrastructure to protect and improve the city’s watershed. Widespread support for the

  18. Effects of Using a Neuroeducational Intervention to Enhance Perseverance for Online EdD and EdS Students

    ERIC Educational Resources Information Center

    Cadle, Charles R.

    2013-01-01

    Developing and maintaining a "completion mindset" is a necessary mental condition for online educational doctorate (EdD) and educational specialist (EdS) students to obtain their advanced degrees. The purpose of this research study was to examine the effect of a neuroeducational intervention on a volunteer convenience sample of EdD and…

  19. Restructuring Philadelphia's Neighborhood High Schools: A Conversation with Constance Clayton and Michelle Fine.

    ERIC Educational Resources Information Center

    Schwartz, Robert

    1994-01-01

    This interview with Constance Clayton, superintendent of the Philadelphia (Pennsylvania) public schools, and Michelle Fine, professor of psychology and consultant, discusses the Philadelphia Schools Collaborative, a nonprofit organization established to lead the restructuring of the city's high schools. Central to the effort is the concept of…

  20. School Restructuring in Philadelphia: Management Lessons from 2002 to 2005. ECS Case Study

    ERIC Educational Resources Information Center

    Rhim, Lauren Morando

    2005-01-01

    In fall 2001, Pennsylvania initiated a "friendly takeover" of the School District of Philadelphia and embarked upon what at the time was characterized as the "largest-scale privatization of public schools ever undertaken." Under the guidance of a School Reform Commission comprising members appointed by the governor and the mayor of Philadelphia,…

  1. A Study of Southeast Asian Youth in Philadelphia: A Final Report.

    ERIC Educational Resources Information Center

    Peters, Heather A.

    This report describes and analyzes the current employment and educational pursuits of Southeast Asian (SEA) youth in the Philadelphia, Pennsylvania, community. The report provides information on the following: (1) demography, residential patterns, and composition of the Philadelphia SEA Refugee Community; (2) role of ethnic identity among the SEA…

  2. The Economic Impact of Community College of Philadelpia on the Philadelphia Area. Report #18.

    ERIC Educational Resources Information Center

    Philadelphia Community Coll., PA. Office of Institutional Research.

    This report presents results of a study of the economic impact of the Community College of Philadelphia (CCP) on the Philadelphia area. After introductory material highlights the origin of the study in a survey of the collective impact of all two- and four-year colleges and universities on the economy of the state, the paper discusses the role and…

  3. School Leadership and Reform: Case Studies of Philadelphia Principals. Occasional Paper.

    ERIC Educational Resources Information Center

    Spiri, Mary Helen

    This report is the result of a 10-month study of 12 principals in the School District of Philadelphia. The research included in the report is part of a body of qualitative data collected about schools engaged in Philadelphia's Children Achieving reform agenda. The report explores the nature of emerging responsibilities, the ways in which…

  4. The Philadelphia Partnership: Improving College Access and Retention Among Minority and Low-Income Students.

    ERIC Educational Resources Information Center

    Ender, Steven C.; Wiley, Byron A.; Pagano, Charles

    1998-01-01

    The Philadelphia Partnership is a Philadelphia School District (Pennsylvania) program, sponsored by the state higher education system and designed to increase the number of low-income and minority students in comprehensive, neighborhood magnet schools who attend college and graduate. A hundred sophomores are selected annually to participate in the…

  5. Philadelphia's Renaissance Schools: A Report on Start up and Early Implementation

    ERIC Educational Resources Information Center

    Gold, Eva; Good, Deborah; Robertson-Kraft, Claire; Callahan, M. Kate

    2011-01-01

    In April 2009, Superintendent Arlene Ackerman announced her reform plan for the School District of Philadelphia (the District)--"Imagine 2014". Among other major initiatives, "Imagine 2014" laid the groundwork for Philadelphia's Renaissance Schools Initiative. The Renaissance Initiative, set to enter its second year in 2011-12, is an effort to…

  6. Time's Up: Applying Teacher Management Skills to Solving Philadelphia's Problems

    ERIC Educational Resources Information Center

    Lax, Zach

    2013-01-01

    Teachers are natural problem solvers, and they should be using this quality to their advantage when it comes to solving the systemic issues that plague Philadelphia's education system. Many of the articles in this issue have already gone into great detail about what is happening in Philadelphia. Torch Lytle has provided a summary of the…

  7. Grow Your Own School Leaders: A Case Study of Principal Development in Philadelphia Schools

    ERIC Educational Resources Information Center

    Urban Education Collaborative, 2010

    2010-01-01

    In 2004-05, the School District of Philadelphia (SDP) began a groundbreaking partnership with the Eli Broad Foundation to develop the Academy for Leadership in Philadelphia Schools (ALPS), one of several Broad-funded, alternative principal development programs initiated across the country. The ALPS effort was designed to respond to two challenges:…

  8. How Students Are Leading Us: Youth Organizing and the Fight for Public Education in Philadelphia

    ERIC Educational Resources Information Center

    Conner, Jerusha; Rosen, Sonia

    2013-01-01

    Philadelphia has a rich history of high school student activism, stretching back to 1967, when 3,500 Philadelphia students walked out of their schools, marched to the Board of Education, and demanded the addition of black history courses taught by black teachers, the removal of police from high schools, and an increase in the hiring of black…

  9. WWC Review of the Report "Philadelphia's Renaissance Schools Initiative: 18 Month Interim Report"

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2012

    2012-01-01

    The study reviewed in this report examined the effects of Philadelphia's "Renaissance Schools Initiative" on students in K-8 schools after one year of implementation. Schools were selected for participation based on their School Performance Index (SPI) at the start of the 2010-11 school year. The SPI rates every school in Philadelphia from one to…

  10. School Budget Report for School District of Philadelphia: School Year 2008-2009

    ERIC Educational Resources Information Center

    Education Resource Strategies, 2009

    2009-01-01

    In the fall of 2007, Education Resource Strategies (ERS) was invited by Philadelphia's School Reform Commission to conduct a Resource Use Analysis for the School District of Philadelphia (SDP) that would in part inform a possible transition to weighted student funding. In April 2008, ERS began the first set of interviews and data gathering…

  11. Evaluating the Performance of Philadelphia's Charter Schools. Working Paper WR-550-WPF

    ERIC Educational Resources Information Center

    Zimmer, Ron; Blanc, Suzanne; Gill, Brian; Christman, Jolley

    2008-01-01

    Plagued by long-term poor student outcomes, a number of reforms have been implemented within the Philadelphia School District to improve performance, including the use of charter schools. The number of charter schools in Philadelphia has risen from four to more than 60 over the past decade, and these schools now serve over 30,000 students. Debate…

  12. 78 FR 76779 - Proposed Modification of the Philadelphia, PA, Class B Airspace Area

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ...This action proposes to amend the description of Area G of the Philadelphia Class B airspace area to correct a design error that resulted in the Class B airspace being published 2.1 nautical miles (NM) larger on the southeast side of the area than intended. No other changes to the Philadelphia Class B airspace are being...

  13. Preliminary estimation of the peak discharge at the Su Gologone spring (Central-East Sardinia) during the flood event of November 18th, 2013

    NASA Astrophysics Data System (ADS)

    Cossu, Antonello; De Waele, Jo; Sanna, Francesco; Sanna, Laura

    2014-05-01

    times at the spring, based on the speed of the water taken with a hydraulic reel specially dedicated for this type of survey. These data show that an increase in water level of just 60 cm, produces a flow rate ten times higher than that during low discharge. During the peak discharge at the spring the probe has recorded a rise in the water level of over 11 metres, between 18:00 and 21:00 on November 18th, 2013. Part of this increase, however, was due to the barrier function of the nearby Cedrino river, whose high water level has blocked the drainage of the water from the karst system. The water spring level curve shows a temporary lowering around noon, before the flood peak, probably due to the opening of the dam. On the basis of the comparison between the measured speed of water flow in the stages immediately preceding and succeeding the flood event and of the values of water level recorded by the multi-parametric probe, it has been possible to estimate the contribution of the karst spring to the peak discharge of the river in around 40 cubic metres per second, a value of two orders of magnitude greater than the average flow of the spring (around 200 L/s).

  14. Outbreak of cyclosporiasis associated with imported raspberries, Philadelphia, Pennsylvania, 2000.

    PubMed

    Ho, Alice Y; Lopez, Adriana S; Eberhart, Michael G; Levenson, Robert; Finkel, Bernard S; da Silva, Alexandre J; Roberts, Jacquelin M; Orlandi, Palmer A; Johnson, Caroline C; Herwaldt, Barbara L

    2002-08-01

    An outbreak of cyclosporiasis occurred in attendees of a wedding reception held in Philadelphia, Pennsylvania, on June 10, 2000. In a retrospective cohort study, 54 (68.4%) of the 79 interviewed guests and members of the wedding party met the case definition. The wedding cake, which had a cream filling that included raspberries, was the food item most strongly associated with illness (multivariate relative risk, 5.9; 95% confidence interval, 3.6 to 10.5). Leftover cake was positive for Cyclospora DNA by polymerase chain reaction analyses. Sequencing of the amplified fragments confirmed that the organism was Cyclospora cayetanensis. The year 2000 was the fifth year since 1995 that outbreaks of cyclosporiasis definitely or probably associated with Guatemalan raspberries have occurred in the spring in North America. Additionally, this is the second documented U.S. outbreak, and the first associated with raspberries, for which Cyclospora has been detected in the epidemiologically implicated food item. PMID:12141962

  15. Geophysical investigation at Philadelphia Naval Shipyard. Final report,

    SciTech Connect

    Sharp, M.K.

    1992-03-01

    Results of a geophysical investigation at the incinerator site of Philadelphia Naval Shipyard are presented. Following the end of World War II, 50 to 60 pallets of gas cylinders were reportedly buried to the west of the old incinerator at Girard Point. The contents of the cylinders are unknown. Extensive filling operations occurred at Girard Point from 1940 to 1970, resulting in shallow groundwater surface in the area, 2 to 10 ft deep, which would indicate that the cylinders are probably in direct contact with the water surface. The geophysical investigation presented in this report was designed to help alleviate uncertainties produced from previous studies in the area. The geophysical program included electromagnetic induction and magnetic survey methods. The results of the various surveys were integrated, and numerous anomalous areas were interpreted. Anomalies warranting further investigation were presented along with a priority ranking.

  16. Learning From Philadelphia: Topographies of HIV/AIDS Media Assemblages.

    PubMed

    Cartwright, Lisa

    2016-01-01

    For this contribution to the special issue on "Mapping Queer Bioethics," the author employs an array of public health and popular media texts (especially Jonathan Demme's film Philadelphia) to challenge the construction and reconstruction of HIV-positive bodies as sites of bioethical concern. In outlining notions of "digital restoration," the author argues that there has been of late a remapping of the first decade of the HIV/AIDS pandemic through media projects assembled from archived materials. Accordingly, the author suggests that in the first decades of the 2000s, we have witnessed a media-archaeological turn, whereby old materials have been reassembled for commemorative purposes that oftentimes perform a reshaping of the topography of the first decade of the AIDS pandemic. PMID:26642876

  17. What Is Ag-Ed?

    ERIC Educational Resources Information Center

    Linley, Judy; Mylne, Lee

    1998-01-01

    Ag-Ed, an agricultural education project for upper elementary students, was held in conjunction with the Toowoomba Show in Queensland, Australia. Agriculture industry representatives provided 20 interactive agricultural presentations for class groups, which were supplemented with a teacher resource-package containing a directory and 13 sections of…

  18. Overview of Deployed EDS Technologies

    SciTech Connect

    Martz, H E; Crawford, C

    2009-09-24

    The term explosive detection system (EDS) is used by the TSA to describe equipment that is certified to detect explosives in checked bags. The EDS, as certified, by the TSL must consist of device for interrogating a bag and an automated detection algorithm (ATD) for evaluating the results of the interrogation. We only consider CT as the interrogation device in this report. A schematic drawing of a CT-based EDS is shown in Figure 2. The output of the ATD is the binary decision of alarm or non-alarm. Alarms may true- or false-positives. Non-alarms may be true- or false-negatives. False positives are also denoted false alarms. The true detection means that the ATD reports an alarm when a threat is present in the scanned bag. The probability of detecting a threat given that a threat is present is denoted the probability of detection (PD). The probability of false alarm (PFA) is the case when an alarm is reported when a threat is not present in a bag. Certification in this context means passing tests for PD and PFA at the TSL. The results of the EDS include CT cross-sectional images of the bag and specifics about the alarmed objects generated by ATD. These results are presented on a display so that a person may override the decision of ATD and declare the alarm to be a non-alarm. This process is denoted clearing. Bags that are not cleared by the person are sent to a secondary inspection process. Here the bags may be opened or assessed with explosive trace detection (ETD) in order to clear the bags. Bags that are not cleared at this point are evaluated by an ordinance disposal team. The CT scanner along with ATD is denoted Level 1 screening. The process of clearing on a display is denoted Level 2 screening. Secondary inspection is denoted Level 3 screening. Vendors of the deployed EDSs supply the TSA with equipment for all three levels. Therefore, the term EDS may include the equipment provided for Levels 1, 2 and 3. A schematic diagram of an EDS and the levels of

  19. Redesigning physician compensation and improving ED performance.

    PubMed

    Finkelstein, Jeff; Lifton, James; Capone, Claudio

    2011-06-01

    Redesigning a physician compensation system in the emergency department (ED) should include goals of improving quality, productivity, and patient satisfaction. Tips for hospital administrators: A contemporary ED information system is needed to ensure that the ED is essentially a paperless operation. Transparency, internally and externally, is essential. ED physicians should perform as individuals, yet as members of a team. Incentives, especially incentive compensation, should strike a balance between individual and team performance. PMID:21692383

  20. Using Local History To Understand National Themes: The Yellow Fever Epidemic in Philadelphia in 1793.

    ERIC Educational Resources Information Center

    Westbury, Susan

    2003-01-01

    Provides background information for a local history project about the 1793 Philadelphia (Pennsylvania) yellow fever outbreak. Offers potential project topics to help students learn about local history and understand life in the eighteenth century United States. (CMK)

  1. 75 FR 21386 - Philadelphia International Airport, Capacity Enhancement Program, Environmental Impact Statement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Federal Aviation Administration Philadelphia International Airport, Capacity Enhancement Program, Environmental Impact Statement, Announcement of a Preferred Alternative AGENCY: Federal Aviation Administration... L. McDonald, Environmental Protection Specialist, Federal Aviation Administration,...

  2. Public Health and Law Collaboration: The Philadelphia Lead Court Study

    PubMed Central

    Gracely, Ed; Pan, Sarah; Cummings, Curtis; Palermo, Peter; Gould, George

    2013-01-01

    Objectives. We determined whether Philadelphia Lead Court is effective in enforcing lead hazard remediation in the homes of children with elevated blood lead levels. Methods. We created a deidentified data set for properties with an initial failed home inspection (IFHI) for lead hazards from January 1, 1998, through December 31, 2008, and compared compliance rates within the first year and time to compliance for lead hazard remediation between 1998 and 2002 (precourt period) and between 2003 and 2008 (court period). We evaluated predictors of time to compliance. Results. Within 1 year of the IFHI, 6.6% of the precourt and 76.8% of the court cases achieved compliance (P < .001) for the 3764 homes with data. Four years after the IFHI, 18% had attained compliance in the precourt period compared with 83.1% for the court period (P < .001). A proportional hazard analysis found that compliance was 8 times more likely in the court than the precourt period (P < .001). Conclusions. Lead court was more effective than precourt enforcement strategies. Most properties were remediated within 1 year of the IFHI, and time to compliance was significantly reduced. This model court could be replicated in other cities with similar enforcement problems. PMID:23678927

  3. Transgender health: findings from two needs assessment studies in Philadelphia.

    PubMed

    Kenagy, Gretchen P

    2005-02-01

    HIV/AIDS, suicide, violence, and barriers to health care access among transgender people were explored using two needs assessment surveys conducted in Philadelphia in 1997. A total of 182 people responded to a face-to-face interview or self-administered mail survey: 113 male-to-female individuals and 69 female-to-male individuals. About three-fifths of respondents had engaged in unprotected sexual activity during the past 12 months. The risk for HIV infection from unprotected sex was significantly higher among respondents of color than among white respondents. About one-third (30.1 percent) of respondents had attempted suicide. More than half of respondents had been forced to have sex, 56.3 percent had experienced violence in their homes, and 51.3 percent had been physically abused. Twenty-six percent of respondents had been denied medical care because they were transgender. These findings suggest that prevention services that specifically address HIV/AIDS, suicide, and violence among transgender people are urgently needed. PMID:15847234

  4. Philadelphia Electric Company's computer replacement lessons learned at Peach Bottom

    SciTech Connect

    Clark, J.M.; O'Hara, J.

    1989-01-01

    The current regulatory climate continues to prod today's nuclear utilities toward safer and more reliable operation of their plants. U.S. Nuclear Regulatory Commission guides NUREG-0660, NUREG-0696, and Supplement I to NUREG-0737 have all set forth increased requirements for plant monitoring. In response, the industry has looked at their existing plant computer systems as targets for enhancement or upgrade. This external pressure is nearly matched by the increasing demands made on existing computer systems by utility engineering and operations departments. The longer utilities postpone this evolution, the more likely they are to replace the entire system rather than upgrade the existing one. The older systems become harder to maintain and eventually are technically inferior to new systems, which have benefited from advances in computer technology in recent years. Enhancements become less economically advantageous than system replacements as the spread in technology widens. The object of this paper is to describe the Plant Process Computer Replacement Project at Philadelphia Electric Company's (PECo's) Peach Bottom Atomic Power Station. This paper explores (a) the impact on the plant, (b) the design and engineering services required, and (c) the planning and communication essential to a successful computer replacement project.

  5. Health Status of People Undergoing Foreclosure in the Philadelphia Region

    PubMed Central

    Lynch, Julia

    2009-01-01

    Objectives. We assessed the health status of people undergoing mortgage foreclosure in the Philadelphia region to determine if there was a relationship between foreclosure and health. Methods. Participants were recruited in partnership with a mortgage counseling agency. Participants' health status and health care use were compared with a community sample from the 2008 Southeastern Pennsylvania Household Health Survey. We used publicly filed foreclosure records to assess response bias. Results. Of the 250 people recruited, 36.7% met screening criteria for major depression. The foreclosure sample was significantly more likely than the community sample to not have insurance coverage (adjusted odds ratio [AOR] = 2.28; 95% confidence interval [CI] = 1.49, 3.48) and to not have filled a prescription because of cost in the preceding year (AOR = 3.44; 95% CI = 2.45, 4.83). Approximately 9% of the participants reported that their own or a family member's medical condition was the primary reason they were undergoing foreclosure. More than a quarter of those in foreclosure (27.7%) stated that they owed money to medical creditors. Conclusions. Foreclosure affects already-vulnerable populations. Public health practitioners may be able to leverage current efforts to connect homeowners with mortgage counseling agencies to improve health care access. PMID:19696373

  6. The origins of American physical anthropology in Philadelphia.

    PubMed

    Mann, Alan

    2009-01-01

    With its location on a river with easy access to the sea, its central placement between the English speaking colonies to the north and south and its trading connections with the western frontier, there were many reasons Philadelphia became one of the most important towns of prerevolutionary America. In the early 1770s, it was the site of the first meeting organized to deal with the perceived inequities of the British government toward the colonies. It was where Thomas Jefferson wrote much of the Declaration of Independence, whose soaring statements reflecting the Age of Enlightenment spoke of the equality of all men. It was to this debate, centered on just who was included in this declaration that the origins of physical anthropology in America can be traced. Notable men in the early phases of this disputation included Samuel Stanhope Smith and especially Samuel George Morton, considered the founder of American physical anthropology. The American School of Anthropology, which argued for the polygenic origins of human races was substantially founded on Morton's work. Recent accusations that Morton manipulated data to support his racist views would appear unfounded. The publication of The Origin of Species in 1859 and the issuing of the Emancipation Proclamation in 1862-63 effectively ended the earlier debates. By the time of the American Civil War, 1861-65, physical anthropology was beginning to explore other topics including growth and development and anthropometry. PMID:19890866

  7. Interpretations of cigarette advertisement warning labels by Philadelphia Puerto Ricans.

    PubMed

    Morris, Nancy; Gilpin, Dawn R; Lenos, Melissa; Hobbs, Renee

    2011-09-01

    This study examined Philadelphia Puerto Ricans' interpretations of the Surgeon General's warnings that appear on cigarette packaging and in advertisements. In-home family focus groups in which participants were asked to comment on magazine cigarette advertisements showed a great variety of interpretations of the legally mandated warning labels. These findings (a) corroborate and add to research in public health and communications regarding the possibility of wide variations in message interpretations and (b) support the call for public health messages to be carefully tested for effectiveness among different social groups. The article's focus on Puerto Ricans addresses the problem of misleading conclusions that can arise from aggregating all Latino subpopulations into one group. The use of a naturalistic setting to examine interpretations of messages about smoking departs from the experimental methods typically used for such research and provides new evidence that even a seemingly straightforward message can be interpreted in multiple ways. Understanding and addressing differences in message interpretation can guide public health campaigns aimed at reducing health disparities. PMID:21534024

  8. Short form Philadelphia Naming Test: Rationale and Empirical Evaluation

    PubMed Central

    Walker, Grant M.; Schwartz, Myrna F.

    2012-01-01

    Purpose To create two matched short forms of the Philadelphia Naming Test (PNT) that yield similar results to the PNT for measuring anomia. Methods Study 1: We first used archived naming data from 94 aphasic individuals to identify which PNT items should be included in the short forms, and the two constructed sets of 30 items, PNT30-A and PNT30-B, were validated using archived data from a separate group of 56 aphasic individuals. Study 2: We then evaluated the reliability of the PNT, PNT30-A, and PNT30-B across independent test administrations with a new group of 25 aphasic individuals selected to represent the full range of naming impairment. Results Study 1: PNT30-A and PNT30-B were found to be internally consistent; and accuracy scores on these subsets of items were highly correlated with the full PNT. Study 2: PNT accuracy was extremely reliable over the span of one week; and independent administrations of PNT30-A and PNT30-B produced similar results to the PNT and to each other. Conclusions The short forms can be used to reliably estimate PNT performance, and the results can be compared to the provided norms. The two matched tests allow for measurement of change in naming ability. PMID:22294412

  9. Increased mortality in Philadelphia associated with daily air pollution concentrations

    SciTech Connect

    Schwartz, J.; Dockery, D.W. )

    1992-03-01

    Cause-specific deaths by day for the years 1973 to 1980 in Philadelphia, Pennsylvania, were extracted from National Center for Health Statistics mortality tapes. Death from accidents (International Classification of Disease, Revision 9 greater than or equal to 800) and deaths outside of the city were excluded. Daily counts of deaths were regressed using Poisson regression on total suspended particulate (TSP) and/or SO2 on the same day and on the preceding day, controlling for year, season, temperature, and humidity. A significant positive association was found between total mortality (mean of 48 deaths/day) and both TSP (second highest daily mean, 222 micrograms/m3) and SO2 (second highest daily mean, 299 micrograms/m3). The strongest associations were found with the mean pollution of the current and the preceding days. Total mortality was estimated to increase by 7% (95% CI, 4 to 10%) with each 100-micrograms/m3 increase in TSP, and 5% (95% CI, 3 to 7%) with each 100-micrograms/m3 increase in SO2. When both pollutants were considered simultaneously, the SO2 association was no longer significant. Mortality increased monotonically with TSP. The effect of 100 micrograms/m3 TSP was stronger in subjects older than 65 yr of age (10% increase) compared with those younger than 65 yr of age (3% increase). Cause-specific mortality was also associated with a 100-micrograms/m3 increase in TSP: chronic obstructive pulmonary disease (ICD9 490-496), +19% (95% CI, 0 to 42%), pneumonia (ICD9 480-486 and 507), +11% (95% CI, -3 to +27%), and cardiovascular disease (ICD9 390-448), +10% (95% CI, 6 to 14%). These results are somewhat higher than previously reported associations, and they add to the body of evidence showing that particulate pollution is associated with increased daily mortality at current levels in the United States.

  10. Chronic myelogenous leukemia (CML) with variant Philadelphia chromosome

    SciTech Connect

    Lorch, C.A.; Burkart, P.T.; Estman, A.

    1994-09-01

    Approximately 95% of patients with CML have the Philadelphia chromosome (Ph). Less than 10% of these have variant translocations. A 39-year-old male was diagnosed with CML after bone marrow examination. Cytogenetic studies showed a variant Ph chromosome, 46,X,t(16;22)(p13,q11), with chromosome 9 appearing cytogenetically normal. Southern blot analysis of peripheral blood showed BCR rearrangement within the 5.8 kb major breakpoint region. Reverse transriptase PCR (RT-PCR) studies confirmed the involvement of the C-ABL gene from chromosome 9. One year later, prior to matched unrelated transplant, a repeat marrow showed t(3;21) in addition to the variant Ph chromosome. Five months post-transplant, bone marrow showed only normal 46,XX donor cells and BCR rearrangement was not detectable by secondary RT-PCR. Two months later, a nodule, which proved to be a chloroma, was removed from the skin. Molecular studies of nodular DNA showed BCR rearrangement and cytogenetic studies showed karyotypic progression: 45,XY,t(3;21),t(4;8),t(16;22),-7. The patient`s marrow continued to show normal 46,XX donor chromosomes, but secondary RT-PCR studies showed marrow involvement. The disease progressed and the patient died. This case is remarkable for the rare variant Ph translocation, the extramedullary and skin disease progression, and the monitoring with secondary RT-PCR studies, along with cytogenetic analysis. These techniques, combined, lead to a more accurate assessment and follow-up of the disease progression.

  11. Diversity of breakpoints of variant Philadelphia chromosomes in chronic myeloid leukemia in Brazilian patients

    PubMed Central

    Chauffaille, Maria de Lourdes Lopes Ferrari; Bandeira, Ana Carolina de Almeida; da Silva, Aline Schiavoni Guarnieri

    2014-01-01

    Background Chronic myeloid leukemia is a myeloproliferative disorder characterized by the Philadelphia chromosome or t(9;22)(q34.1;q11.2), resulting in the break-point cluster region-Abelson tyrosine kinase fusion gene, which encodes a constitutively active tyrosine kinase protein. The Philadelphia chromosome is detected by karyotyping in around 90% of chronic myeloid leukemia patients, but 5–10% may have variant types. Variant Philadelphia chromosomes are characterized by the involvement of another chromosome in addition to chromosome 9 or 22. It can be a simple type of variant when one other chromosome is involved, or complex, in which two or more chromosomes take part in the translocation. Few studies have reported the incidence of variant Philadelphia chromosomes or the breakpoints involved among Brazilian chronic myeloid leukemia patients. Objective The aim of this report is to describe the diversity of the variant Philadelphia chromosomes found and highlight some interesting breakpoint candidates for further studies. Methods the Cytogenetics Section Database was searched for all cases with diagnoses of chronic myeloid leukemia during a 12-year period and all the variant Philadelphia chromosomes were listed. Results Fifty (5.17%) cases out of 1071 Philadelphia-positive chronic myeloid leukemia were variants. The most frequently involved chromosome was 17, followed by chromosomes: 1, 20, 6, 11, 2, 10, 12 and 15. Conclusion Among all the breakpoints seen in this survey, six had previously been described: 11p15, 14q32, 15q11.2, 16p13.1, 17p13 and 17q21. The fact that some regions get more frequently involved in such rare rearrangements calls attention to possible predisposition that should be further studied. Nevertheless, the pathological implication of these variants remains unclear. PMID:25638762

  12. Instability of EDS maglev systems

    SciTech Connect

    Cai, Y.; Chen, S.S.

    1993-09-01

    Instabilities of an EDS maglev suspension system with 3 D.O.F. and 5 D.O.F. vehicles traveling on a double L-shaped set of guideway conductors have been investigated with various experimentally measured magnetical force data incorporated into the theoretical models. Divergence and flutter are obtained from both analytical and numerical solutions for coupled vibration of the 3 D.O.F. maglev vehicle model. Instabilities of five direction motions (heave, slip, rill, pitch and yaw) are observed for the 4 D.O.F. vehicle model. It demonstrates that system parameters, such as, system damping, vehicle geometry and coupling effects among five different motions play very important roles in the occurrence of dynamic instabilities of maglev vehicles.

  13. Perspective: Academic obstetrics-gynecology departments in the city of Philadelphia: are the wheels coming off?

    PubMed

    Croft, Damien J

    2011-03-01

    Maternity care in Philadelphia is in an unprecedented and precarious situation, as all the community hospitals that once provided maternity care services have either closed completely or stopped providing maternity services. Six academic medical centers (AMCs) in the city of Philadelphia now provide care to a population of 1.5 million requiring increasingly complex and expensive maternity care, at the same time as insurance premiums and the malpractice crisis in Pennsylvania peaked. The AMCs are able to continue providing maternity care to this population that includes a large proportion of poor, minority, and un- or underinsured patients thanks to government subsidization of resident education, the services provided by resident physicians, and the influx of government and industry research funds, but the financial outlook of academic obstetrics-gynecology departments in this city is dire. Obstetric academic medicine in Philadelphia has come to more closely resemble a "big wheel" tricycle than Flexner's "three-legged stool." Clinical medicine is the driver (the large front wheel and pedal) pulling along education and research, the two smaller wheels in the back. A maternity care alliance is needed in Philadelphia allowing area AMCs to pool and trade resources, reduce costs, improve quality and innovation, and share risks. Philadelphia may serve as an early warning for other cities and AMCs around the country and has the opportunity to serve as a model for how to overcome these serious challenges. PMID:21248611

  14. Media campaign educates public on ED overcrowding.

    PubMed

    2004-04-01

    A Tennessee health care system is reducing overcrowding in its EDs with a media campaign that urges patients with nonurgent needs to seek other care options. The campaign has contributed to a 5% decrease in ED volume at one hospital in the first few months. Advertising spots urge patients to go to primary care physicians and urgent care clinics. ED staff help educate patients while treating them for nonurgent needs. PMID:15077530

  15. Tick-borne encephalitis-still on the map: Report of the 18th annual meeting of the international scientific working group on tick-borne encephalitis (ISW-TBE).

    PubMed

    Kunze, Ursula

    2016-07-01

    The 18th meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE)-a group of neurologists, general practitioners, clinicians, travel physicians, virologists, pediatricians and epidemiologists-was held under the title 'Tick-borne encephalitis-still on the map'. The conference agenda was divided into six sessions: 'National Implementation of EU notifiable disease status', 'Virology', 'Epidemiology and Risk areas & Poster Walk Epidemiological Update', 'Clinic', 'Environmental Factors' and 'New Findings and Diagnosis'. Key topics such as 'TBE as a notifiable disease-results of the third European survey', 'TBE vaccines over the years', 'Overview of flaviviruses', 'TBE virus phylogenetics', 'Current epidemiological developments and investigations', 'Clinical aspects', 'TBE in veterinary medicine', 'Laboratory diagnostic', 'Occupational risk', 'Allergy, obesity, and vaccination' were presented and extensively discussed. PMID:27189584

  16. The men of Nelson's navy: a comparative stable isotope dietary study of late 18th century and early 19th century servicemen from Royal Naval Hospital burial grounds at Plymouth and Gosport, England.

    PubMed

    Roberts, Patrick; Weston, Sam; Wild, Bastien; Boston, Ceridwen; Ditchfield, Peter; Shortland, Andrew J; Pollard, A Mark

    2012-05-01

    We present stable isotopic analyses of collagen from 80 servicemen excavated from the late 18th/early 19th century naval hospitals at Plymouth (50) and Haslar, Gosport (30) in southern England. Historical records suggest that, the diets of these two populations should be essentially identical. While δ(15) N of the rib collagen confirmed that naval servicemen were relatively well-catered for in terms of meat allowance (Plymouth average δ(15) N = 11.1‰, Gosport = 11.9‰), stable carbon isotope analysis produced average values for the two assemblages, which were significantly different (Plymouth average δ(13) C = -18.8‰, Gosport = -20.0‰). We postulate that these differences stem from divergent naval postings, with a greater proportion of Plymouth individuals serving in areas that entailed a greater input of C(4) foodstuffs. By comparison with published data from approximately contemporary burials at Snake Hill, Ontario, Canada and Chesapeake Bay, Virginia, we suggest that this area is the east coast of North America. For 15 of the 30 individuals from Gosport, we have data on ribs, femur, and dentine from the same skeleton, which appear to show that they came from a variety of locations in their preadolescence, but converged in dietary terms onto a "naval average," which is consistent with historical evidence for recruitment patterns into the Navy at the time. By comparison with published data from skeletons recovered from the wreck of the Mary Rose (sank 1545), we conclude that this naval diet was virtually unchanged from the 16th century to the end of the 18th century. PMID:22407735

  17. Aerosol acidity characterization of large metropolitan areas: Pilot and planning for Philadelphia

    SciTech Connect

    Waldman, J.M.; Koutrakis, P.; Burton, R.; Wilson, W.E.; Purdue, L.J.

    1993-01-01

    The report described the EPA's multi-year program to investigate the specific issues surrounding human exposures to aerosol activity. Philadelphia, a large metropolitan area in the heart of the northeastern seaboard afflicted with photochemical regional smog during the summertime, was chosen as the first city in the program. A pilot study of ambient concentrations was conducted in July 1991. An annular denuder system (ADS) sampler was operated for two weeks near downtown Philadelphia, with a second unit operated in central, suburban New Jersey, the same location of measurements in past years. The Philadelphia site was found to have higher concentrations of most major aerosol species, ammonia and acidic particles than in New Jersey, showing that aerosol neutralization within the urban center will not necessarily totally eliminate acidic particle exposures.

  18. Un-Leaded Only: Toward a Safer City for Children. A 2002 Report on Childhood Lead Paint Poisoning in Philadelphia.

    ERIC Educational Resources Information Center

    McCauley, Colleen; Yanoff, Shelly D.; Fynes, Steven E.

    As part of its work in improving the lives and life changes of children in the Philadelphia region, the Philadelphia Citizens for Children and Youth examined the problem of local childhood lead paint poisoning. This report describes their efforts, beginning with a description of the impact of lead poisoning on children's health and a discussion of…

  19. Student Achievement in Privately Managed and District-Managed Schools in Philadelphia Since the State Takeover. Research Brief

    ERIC Educational Resources Information Center

    Gill, Brian; Zimmer, Ron; Christman, Jolley; Blanc, Suzanne

    2007-01-01

    Following a state takeover of the Philadelphia public schools in 2002, 45 schools were turned over to private managers, making Philadelphia the site of the nation's largest experiment in the private management of public schools. This study examines achievement effects in the privately managed schools, as well as in schools with district-led…

  20. Care of the Health of Boys in Girard, College, Philadelphia, Pennsylvania. Bulletin, 1914, No. 40. Whole Number 614

    ERIC Educational Resources Information Center

    United States Bureau of Education, Department of the Interior, 1914

    1914-01-01

    Girard College was founded and endowed by Stephen Girard, mariner and merchant, a native of France, who came to Philadelphia in 1776. After a long life of service to his adopted city, State, and country, he died in 1831, leaving the bulk of his estate in trust to the city of Philadelphia for the erection and maintenance of what is now known as…

  1. 78 FR 40399 - Safety Zone; Fifth Coast Guard District Fireworks Displays, Delaware River; Philadelphia, PA.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Fifth Coast Guard District Fireworks Displays, Delaware River; Philadelphia, PA. AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is temporarily changing the enforcement date of a safety zone for one...

  2. Blurring the Boundaries: A Case Study of Private Sector Involvement in Philadelphia Public Schools

    ERIC Educational Resources Information Center

    Gold, Eva; Christman, Jolley Bruce; Herold, Benjamin

    2007-01-01

    As a result of a state takeover, the School District of Philadelphia has been implementing a "diverse provider model" in which for-profit and nonprofit organizations have been hired as school managers. This study explores the first three years of the model, examining the shift away from the rhetoric of competition to the evolution of a…

  3. SEASONAL ABUNDANCE OF ORGANIC MOLECULAR MARKERS IN URBAN PARTICULATE MATTER FROM PHILADELPHIA, PA

    EPA Science Inventory

    Organic molecular markers were measured in airborne particulate matter (PM10) from the City of Philadelphia North Broad Street air quality monitoring site to identify the seasonal abundances of key tracer compounds together with their dominant sources. Daily PM10...

  4. Educating Women for Art and Commerce: The Philadelphia School of Design, 1848-1932.

    ERIC Educational Resources Information Center

    Walls, Nina de Angeli

    1994-01-01

    Reports on the history and accomplishments of the Philadelphia School of Design for Women (Moore College of Art and Design) during the late 19th and early 20th centuries. Contends that the school negotiated tensions between the market forces of the job market and the individual aspirations of its students. (CFR)

  5. 77 FR 45290 - Proposed Modification of Class B Airspace Area; Philadelphia, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... established the Philadelphia, PA, Terminal Control Area (TCA) with an effective date of March 27, 1975 (39 FR 43710). In 1993, as part of the Airspace Reclassification Final Rule (56 FR 65638), the term ``terminal... Federal Register of November 30, 2010 (75 FR 74127), six informal airspace meetings were held in...

  6. 78 FR 3482 - Self-Regulatory Organizations; Stock Clearing Corporation of Philadelphia; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; Stock Clearing Corporation of Philadelphia; Notice of Filing of Proposed Rule Change With Respect to the Amendment of the By-Laws of Its Parent Corporation, The NASDAQ OMX Group, Inc. December 26,...

  7. School Restructuring in Philadelphia: Management Lessons from 2002 to 2005. ECS Policy Brief

    ERIC Educational Resources Information Center

    Rhim, Lauren Morando

    2005-01-01

    To identify the lessons learned from contracting with private managers in Philadelphia from 2002 to 2005, the author conducted an extensive document review and interviewed state, district and EMO personnel involved with the restructuring process and the specific management structure implemented to administer the Partnership School Model in…

  8. QUANTITATION, DETECTION AND MEASUREMENT PRECISION OF ORGANIC MOLECULAR MARKERS IN URBAN PARTICULATE MATTER FROM PHILADELPHIA, PA

    EPA Science Inventory

    This work focuses on analysis of organic molecular markers in airborne particulate matter (PM) by Gas Chromatography/Ion Trap Mass Spectrometry (GC/IT MS). The particulate samples used in the method development were collected as PM10 in metropolitan Philadelphia during...

  9. The Effect of Local Reform on Title I Schoolwide Programs in Philadelphia. Publication Series No. 5.

    ERIC Educational Resources Information Center

    Wong, Kenneth K.; Sunderman, Gail L.

    In 1995, the Philadelphia (Pennsylvania) school district began an initiative aimed at improving student achievement titled the Children Achieving initiative. This reform agenda introduced 10 components that included local decision making, development of standards, and increased professional development for staff. The Children Achieving agenda is…

  10. Uneven Playing Field: Demographic Differences and High School "Choice" in Philadelphia. Policy Brief

    ERIC Educational Resources Information Center

    Research for Action, 2010

    2010-01-01

    Every fall, eighth graders participate in the School District of Philadelphia's high school application and admissions process, vying for spots in a tiered system of public high schools across the city. This policy brief looks at disparities in the students who are successful in exercising school "choice" in the District's high school selection…

  11. 78 FR 14359 - Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-05

    ... 21, 2012 (77 FR 58583). At the request of a company official, the Department reviewed the... Employment and Training Administration Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA; Verizon Business Networks Services, Inc., Specialist-Tech Customer...

  12. 75 FR 25285 - John Heinz National Wildlife Refuge at Tinicum, Philadelphia and Delaware Counties, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... regular business hours at John Heinz NWR at Tinicum, 8601 Lindbergh Blvd., Philadelphia, PA 19153. FOR... field. The 200 acres of freshwater tidal marsh represents approximately 80 percent of Pennsylvania's..., such as tourism, and local economic impacts; and (6) Coordination and communication issues...

  13. The Assessment of Present-Moment Awareness and Acceptance: The Philadelphia Mindfulness Scale

    ERIC Educational Resources Information Center

    Cardaciotto, LeeAnn; Herbert, James D.; Forman, Evan M.; Moitra, Ethan; Farrow, Victoria

    2008-01-01

    The purpose of this project was to develop a bidimensional measure of mindfulness to assess its two key components: present-moment awareness and acceptance. The development and psychometric validation of the Philadelphia Mindfulness Scale is described, and data are reported from expert raters, two nonclinical samples (n = 204 and 559), and three…

  14. Evaluating an Experiential Learning Program: The GLCA--Philadelphia Urban Semester

    ERIC Educational Resources Information Center

    DeHaan, Robert F.; Van Wagner, Karen

    1977-01-01

    Findings of this study indicate a high positive evaluation by participants of the Great Lakes Colleges Association--Philadelphia Urban Semester program, designed to help students understand the city, develop self-understanding, and to learn about a field of work related to occupational goals. (MB)

  15. Principals' Hiring of Teachers in Philadelphia Schools: A Research Report on Improving Teacher Quality

    ERIC Educational Resources Information Center

    Ramirez, Heidi A.; Schofield, Lynne Steuerle; Black, Melissa

    2009-01-01

    The School District of Philadelphia (SDP), like many other urban school districts, struggles to increase its hiring and retention of experienced and highly qualified teachers in its low-performing/high-need schools. Toward the goal of improving teacher quality and the experience balance, particularly in hard-to-staff schools, the Philadelphia…

  16. Unfulfilled Promise: The Dimensions and Characteristics of Philadelphia's Dropout Crisis, 2000-2005

    ERIC Educational Resources Information Center

    Neild, Ruth Curran; Balfanz, Robert

    2006-01-01

    This report uses a unique set of data obtained from the Kids Integrated Data System (KIDS), which is housed at the University of Pennsylvania's Cartographic Modeling Laboratory. The KIDS system merges individual-level data on young people from the School District of Philadelphia and the city's social service agencies, including the Department of…

  17. The Efficacy of Philadelphia's K-to-8 Schools Compared to Middle Grades Schools.

    ERIC Educational Resources Information Center

    Offenberg, Robert M.

    2001-01-01

    Natural experiments explored the effects of attending public Philadelphia K-to-8 schools or public middle schools on eighth- and ninth-grade achievement. Found that students attending K-8 schools had higher reading, mathematics, and science achievement than students attending middle schools serving similar communities. Suggested that number of…

  18. A Philadelphia Story: Building Civic Capacity for School Reform in a Privatizing System

    ERIC Educational Resources Information Center

    Gold, Eva; Simon, Elaine; Cucchiara, Maia; Mitchell, Cecily; Riffer, Morgan

    2007-01-01

    This report was undertaken to assess the state of civic capacity for education reform in Philadelphia. It challenges community and civic sectors of the city to put aside individual interests and work together to mobilize resources to pursue the collective good of public school improvement. The report demonstrates that many of the elements…

  19. The Black Inner City as Frontier Outpost: Images and Behavior of a Philadelphia Neighborhood. Monograph 7.

    ERIC Educational Resources Information Center

    Ley, David

    While the earth's geography is well known, vast sections of the human landscape are considered to be unsurveyed by scientific explores; In this monograph the world of black America is studied. The boundaries and patterns of a black neighborhood in inner Philadelphia are charted, and its behavioral and environmental characteristics identified. Such…

  20. The Budget Development Process: A Case Study of the Philadelphia School District, 1977.

    ERIC Educational Resources Information Center

    Weiner, Debra S.

    This study analyzes the process used in developing the 1977-78 operating budget of the Philadelphia school district. The purpose of the study was to determine what changes are required to assure greater efficiency and effectiveness in resource allocations in the face of increasingly scarce funds available to urban public school systems. Using a…

  1. Development and Simulation Testing of a Computerized Adaptive Version of the Philadelphia Naming Test

    ERIC Educational Resources Information Center

    Hula, William D.; Kellough, Stacey; Fergadiotis, Gerasimos

    2015-01-01

    Purpose: The purpose of this study was to develop a computerized adaptive test (CAT) version of the Philadelphia Naming Test (PNT; Roach, Schwartz, Martin, Grewal, & Brecher, 1996), to reduce test length while maximizing measurement precision. This article is a direct extension of a companion article (Fergadiotis, Kellough, & Hula, 2015),…

  2. Superintendent's Management Information Center, School District of Philadelphia, 1986-1987.

    ERIC Educational Resources Information Center

    Philadelphia School District, PA. Office of Planning, Research and Evaluation.

    This report provides district administrators with the following information about schools and districts in the Philadelphia Public School System: (1) student characteristics; (2) staff characteristics; (3) attendance data; (4) program data; (5) student performance variables; and (6) graduate data. The report is organized into four sections. The…

  3. An Analysis of the Dial-A-Teacher Assistance Program (DATALINE), School District of Philadelphia.

    ERIC Educational Resources Information Center

    Blackwell, William R.

    The Dial-A-Teacher Assistance project (DATALINE) is a telephone resource center which provides assistance or information to parents and pupils about problems related to homework, as well as information about Parent Partnership activities and services available to parents and children in the School District of Philadelphia. The theory behind the…

  4. 76 FR 49383 - Proposed Amendment of Class D and E Airspace; North Philadelphia, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... Airport, North Philadelphia, PA, due to the closing of Willow Grove Naval Air Station and Warminster NAWC... Specialist, Operations Support Group, Eastern Service Center, Air Traffic Organization, Federal ] Aviation..., views, or arguments, as they may desire. Comments that provide the factual basis supporting the...

  5. Sowing City Schools: Teachers and Garden Education in Havana and Philadelphia

    ERIC Educational Resources Information Center

    Bucher, Katie Ann

    2012-01-01

    This dissertation examines how pedagogies of sustainability are embedded in socio-cultural contexts and policy structures and driven by the localized actions of teachers. Through a comparative case study in two cities with extensive and varied school garden programs, Havana and Philadelphia, this dissertation analyzes the roles, understandings,…

  6. Public Education in Philadelphia: The Crucial Need for Civic Capacity in a Privatized Environment

    ERIC Educational Resources Information Center

    Blanc, Suzanne; Simon, Elaine

    2007-01-01

    Like many other U.S. cities, Philadelphia experienced a prolonged period of deindustrialization and job loss during the second half of the 20th century. As in other northern cities, the process of suburbanization went hand in hand with white flight, increased racial segregation of the city and its schools, and increasingly inadequate funding of…

  7. Reproducibility of the WHO histological criteria for the diagnosis of Philadelphia chromosome-negative myeloproliferative neoplasms.

    PubMed

    Gianelli, Umberto; Bossi, Anna; Cortinovis, Ivan; Sabattini, Elena; Tripodo, Claudio; Boveri, Emanuela; Moro, Alessia; Valli, Riccardo; Ponzoni, Maurilio; M Florena, Ada; F Orcioni, Giulio; Ascani, Stefano; Bonoldi, Emanuela; Iurlo, Alessandra; Gugliotta, Luigi; Franco, Vito

    2014-06-01

    This study, performed on behalf of the Italian Registry of Thrombocythaemias (Registro Italiano Trombocitemie), aimed to test the inter-observer reproducibility of the histological parameters proposed by the WHO classification for the diagnosis of the Philadelphia chromosome-negative myeloproliferative neoplasms. A series of 103 bone marrow biopsy samples of Philadelphia chromosome-negative myeloproliferative neoplasms consecutively collected in 2004 were classified according to the WHO criteria as follows: essential thrombocythaemia (n=34), primary myelofibrosis (n=44) and polycythaemia vera (n=25). Two independent groups of pathologists reviewed the bone marrow biopsies. The first group was asked to reach a collegial 'consensus' diagnosis. The second group reviewed individually all the cases to recognize the main morphological parameters indicated by the WHO classification and report their results in a database. They were subsequently instructed to individually build a 'personal' diagnosis of myeloproliferative neoplasms subtype just assembling the parameters collected in the database. Our results indicate that high levels of agreement (≥70%) have been reached for about all of the morphological features. Moreover, among the 18 evaluated histological features, 11 resulted statistically more useful for the differential diagnosis among the different Philadelphia chromosome-negative myeloproliferative neoplasms. Finally, we found a high percentage of agreement (76%) between the 'personal' and 'consensus' diagnosis (Cohen's kappa statistic >0.40). In conclusion, our results support the use of the histological criteria proposed by the WHO classification for the Philadelphia chromosome-negative myeloproliferative neoplasms to ensure a more precise and early diagnosis for these patients. PMID:24201120

  8. "Welcome to Philadelphia": An Original Dramatization of Life in the 1780s.

    ERIC Educational Resources Information Center

    Stakes, Mary E.

    Teachers can create an interest in the founding period of U.S. history and present students with an authentic view of this time period through the presentation of this play. The dramatic pretense of the play is that the audience, by their presence, is part of the drama. The audience plays the part of travelers visiting a Philadelphia home in the…

  9. Assessing Residential Segregation among Medicaid Recipients with Psychiatric Disability in Philadelphia

    ERIC Educational Resources Information Center

    Metraux, Stephen; Caplan, Joel M.; Klugman, Dutch; Hadley, Trevor R.

    2007-01-01

    This study assesses the extent of residential segregation among 15,246 people diagnosed with psychiatric disabilities and receiving Medicaid (MA) in Philadelphia, and an identically sized group of MA recipients serving as matched controls. Results indicate that overall levels of residential segregation among this group were modest at their most…

  10. Closing the Teacher Quality Gap in Philadelphia: New Hope and Old Hurdles

    ERIC Educational Resources Information Center

    Useem, Elizabeth; Offenberg, Robert; Farley, Elizabeth

    2007-01-01

    In this report, three specific questions guide the analyses that follow: (1) To what degree has the School District of Philadelphia upgraded the teaching credentials of its teachers? (2) How well has the district succeeded in reducing teacher attrition and increasing the experience level of its workforce? (3) Have district efforts since the state…

  11. Closing the Teacher Quality Gap in Philadelphia: New Hope and Old Hurdles. Executive Summary

    ERIC Educational Resources Information Center

    Useem, Elizabeth; Offenberg, Robert; Farley, Elizabeth

    2007-01-01

    This study of teacher staffing issues in the School District of Philadelphia, the third in a series, outlines the degree to which the district has succeeded in upgrading teachers' professional credentials, recruiting and retaining them, and equitably distributing experienced and credentialed teachers across all types of schools. Since the passage…

  12. Getting a Feel for the Market: The Use of Privatized School Management in Philadelphia

    ERIC Educational Resources Information Center

    Byrnes, Vaughan

    2009-01-01

    This study evaluates the impact of the privatization of education services in the Philadelphia School District, using an interrupted time series design. The sample observes 88 middle-grades schools, beginning with the 1996-97 school year, and finds that, by 2006, four years postintervention, the achievement growth rate of schools run by…

  13. Spatial analysis of volatile organic compounds in South Philadelphia using passive samplers

    EPA Science Inventory

    Select volatile organic compounds (VOCs) were measured in the vicinity of a petroleum refinery and related operations in South Philadelphia, Pennsylvania, USA, using passive air sampling and laboratory analysis methods. Two-week, time-integrated samplers were deployed at 17 sites...

  14. Elements of Success: WorkReady Philadelphia Program Year 2011-2012 Report

    ERIC Educational Resources Information Center

    Philadelphia Youth Network, 2012

    2012-01-01

    What does it take to deliver WorkReady Philadelphia's high-quality career-connected programming? In short, it's all about the "elements"--those essential components of the system that combine to produce success for young people. This 2011-12 WorkReady report reinforces this theme by using visual aspects of the "Periodic Table of Elements", which…

  15. A Survey of Automotive Mechanics Programs in the Philadelphia Public Schools. Report No. 8701.

    ERIC Educational Resources Information Center

    Chern, Hermine J.; And Others

    During March and April of 1986, the three members of the Career Education Evaluation Unit of the Philadelphia (Pennsylvania) School District interviewed 29 automotive mechanics teachers working at nine comprehensive high schools, two vocational technical schools, and two skills centers. The interviews focused on the implementation of standardized…

  16. Contracting Out Schools: The First Year of the Philadelphia Diverse Provider Model

    ERIC Educational Resources Information Center

    Bulkley, Katrina; Mundell, Leah; Riffer, Morgan

    2004-01-01

    Educators nationwide focused on Philadelphia in the summer of 2001 as politicians and policy makers explored the possibility of a state takeover of the city's school system, a seismic power shift that would produce the largest privatization of a public school district in American history. The findings reported in this document are based on…

  17. 76 FR 409 - Philadelphia International Airport, Capacity Enhancement Program, Environmental Impact Statement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ..., 2010 (75 FR 52736). The Final EIS was prepared in compliance with the National Environmental Policy Act... Metropolitan Area during all weather conditions. This ROD sets forth FAA's final determination and... demand in the Philadelphia Metropolitan Area during all weather conditions. The Environmental...

  18. Use of Subsidized Child Care by Philadelphia Families: Findings and Discussion.

    ERIC Educational Resources Information Center

    Sterman, Sara Vernon; Dichter, Harriet

    The study examined the consequences of delay in enrollment in subsidized child care and the impact of funding on the choices and perceived opportunities of families once they begin receiving child care subsidies. Subjects were 106 working families in Philadelphia who are either using subsidized child care or who are waiting to enroll in the…

  19. The Launch of the Philadelphia Education Research Consortium: Lessons Learned from the First Year of Implementation

    ERIC Educational Resources Information Center

    Shaw, Kate

    2016-01-01

    The Philadelphia Education Research Consortium (PERC) was launched in July 2014 as an innovative place-based consortium of educational research partners from multiple sectors. Its primary objective is to provide research and analyses on some of the city's most pressing education issues. As such, PERC's research agenda is driven by both traditional…

  20. What Works Clearinghouse Quick Review: "Philadelphia's Renaissance Schools Initiative: 18 Month Interim Report"

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2012

    2012-01-01

    The study examined the effectiveness of Philadelphia's Renaissance Schools Initiative after one year of implementation. The Renaissance Schools Initiative, which began in the 2010-11 school year, aimed at improving low-performing schools by providing new management, additional resources, and new educational strategies. The study reported that…

  1. Context, Conditions, and Consequences: Freshman Year Transition in Philadelphia. Policy Brief

    ERIC Educational Resources Information Center

    Gold, Eva; Evans, Shani Adia; Haxton, Clarisse; Maluk, Holly Plastaras; Mitchell, Cecily A.; Simon, Elaine; Good, Deborah

    2010-01-01

    This policy brief focuses on the School District of Philadelphia's high school selection process and the ways in which it reinforces and compounds inequities that already exist among the District's tiered system of selective, non-selective, and charter high schools. Focused in particular on the impact that these policies have on non-selective…

  2. School District of Philadelphia School Closings: An Analysis of Student Achievement

    ERIC Educational Resources Information Center

    Research For Action, 2013

    2013-01-01

    For any school closing policy to minimize adverse effects on student achievement, students from closed buildings should be placed in higher performing ones. To provide a more in-depth analysis of the potential academic impacts of the School District of Philadelphia's proposed school closure plan, Research for Action (RFA) compared 32 schools…

  3. 75 FR 80568 - Proposed Modification of the Philadelphia, PA, Class B Airspace Area; Public Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... Philadelphia, PA (75 FR 74127). The name and phone number of the person to contact for further information has subsequently been changed. This action provides the correct information. Correction In notice of meetings FR Doc. 2010-30085, as published on November 30, 2010 (75 FR 74127) on page 74127, column two, make...

  4. ASSOCIATIONS BETWEEN PARTICULATE MATTER COMPONENTS AND DAILY MORTALITY AND MORBIDITY IN PHILADELPHIA, PA

    EPA Science Inventory

    In evaluating the health risks from particulate matter (PM), the question remains as to which component(s) of PM are most harmful. We investigated this issue using PM mass, PM constituents, mortality, and the elderly hospital admission data in Philadelphia, PA. Daily paired PM...

  5. Turning It around: A Collective Effort to Understand and Resolve Philadelphia's Dropout Crisis

    ERIC Educational Resources Information Center

    Philadelphia Youth Network, 2006

    2006-01-01

    Today and every day, in neighborhoods and communities throughout Philadelphia, young people are making decisions that will change their lives forever. Some will decide to stay in school, graduate, and prepare themselves for college and careers. Others, who left school without a diploma, will summon the courage to seek out educational programs they…

  6. Extension, Communities, and Schools: Results of a Collaborative Forestry Education Project in Philadelphia.

    ERIC Educational Resources Information Center

    Broussard, Shorna R.; Jones, Stephen B.

    2001-01-01

    Penn State Extension, Philadelphia community leaders, school district administrators, and teachers developed a comprehensive program to teach inner-city youth about forestry and forest management. Evaluation results indicate that students were more knowledgeable about forestry and forest management; teachers were more likely to use natural…

  7. Symposium (International) on Combustion, 18th, 1980

    SciTech Connect

    Anon

    1980-08-01

    This conference proceedings contains 196 papers. 181 papers are indexed separately. Topics covered include: combustion generated pollution; propellant combustion; fluidized bed combustion; combustion of droplets and spray; premixed flame studies; fire studies; flame stabilization; coal flammability; chemical kinetics; turbulent combustion; soot; coal combustion; modeling of combustion processes; combustion diagnostics; detonations and explosions; ignition; internal combustion engines; combustion studies; and furnaces.

  8. 18th Annual School Construction Report, 2013

    ERIC Educational Resources Information Center

    Abramson, Paul

    2013-01-01

    The bottom line on school construction in 2012 is that total spending edged up slightly from the previous year, (to $12.9 billion from $12.2 billion), but the spending for new schools declined from $6.9 billion to $6.177 billion. The increase in overall spending was attributable to more spending for additions and a major increase in spending for…

  9. 18th Annual Residence Hall Construction Report

    ERIC Educational Resources Information Center

    Agron, Joe

    2007-01-01

    It is said that "home is where the heart is." Many colleges and universities are keeping that in mind as they continue to invest in building residential facilities to attract students to on-campus living. Residence hall construction at the nation's higher-education institutions remains strong, as the benefits to students, parents, and the college…

  10. The 18th Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Topics concerning aerospace mechanisms, their functional performance, and design specifications are presented. Discussed subjects include the design and development of release mechanisms, actuators, linear driver/rate controllers, antenna and appendage deployment systems, position control systems, and tracking mechanisms for antennas and solar arrays. Engine design, spaceborne experiments, and large space structure technology are also examined.

  11. Mechanical Ventilation and ARDS in the ED

    PubMed Central

    Mohr, Nicholas M.; Miller, Christopher N.; Deitchman, Andrew R.; Castagno, Nicole; Hassebroek, Elizabeth C.; Dhedhi, Adam; Scott-Wittenborn, Nicholas; Grace, Edward; Lehew, Courtney; Kollef, Marin H.

    2015-01-01

    BACKGROUND: There are few data regarding mechanical ventilation and ARDS in the ED. This could be a vital arena for prevention and treatment. METHODS: This study was a multicenter, observational, prospective, cohort study aimed at analyzing ventilation practices in the ED. The primary outcome was the incidence of ARDS after admission. Multivariable logistic regression was used to determine the predictors of ARDS. RESULTS: We analyzed 219 patients receiving mechanical ventilation to assess ED ventilation practices. Median tidal volume was 7.6 mL/kg predicted body weight (PBW) (interquartile range, 6.9-8.9), with a range of 4.3 to 12.2 mL/kg PBW. Lung-protective ventilation was used in 122 patients (55.7%). The incidence of ARDS after admission from the ED was 14.7%, with a mean onset of 2.3 days. Progression to ARDS was associated with higher illness severity and intubation in the prehospital environment or transferring facility. Of the 15 patients with ARDS in the ED (6.8%), lung-protective ventilation was used in seven (46.7%). Patients who progressed to ARDS experienced greater duration in organ failure and ICU length of stay and higher mortality. CONCLUSIONS: Lung-protective ventilation is infrequent in patients receiving mechanical ventilation in the ED, regardless of ARDS status. Progression to ARDS is common after admission, occurs early, and worsens outcome. Patient- and treatment-related factors present in the ED are associated with ARDS. Given the limited treatment options for ARDS, and the early onset after admission from the ED, measures to prevent onset and to mitigate severity should be instituted in the ED. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT01628523; URL: www.clinicaltrials.gov PMID:25742126

  12. Expedition 7 Crew Interview: Ed Lu

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Ed Lu of Expedition Seven is seen during a pre-launch interview. He explains why he became interested in space flight. He states that this is a different type of mission and gives his reaction to the Columbia Space Shuttle tragedy. The handover of Expedition six is explained by Ed Lu. The challenges of this mission are also described by Lu. These challenges include working with a crew member reduction from three to two, and the conservation of clothing and consumables. Ed Lu talks about what it is like to work with commander Yuri Malenchenko in space. Finally, Ed Lu states that he will continue scientific experiments in space on calcium loss in bones.

  13. MicroED data collection and processing

    SciTech Connect

    Hattne, Johan; Reyes, Francis E.; Nannenga, Brent L.; Shi, Dan; Cruz, M. Jason de la; Leslie, Andrew G. W.; Gonen, Tamir

    2015-07-01

    The collection and processing of MicroED data are presented. MicroED, a method at the intersection of X-ray crystallography and electron cryo-microscopy, has rapidly progressed by exploiting advances in both fields and has already been successfully employed to determine the atomic structures of several proteins from sub-micron-sized, three-dimensional crystals. A major limiting factor in X-ray crystallography is the requirement for large and well ordered crystals. By permitting electron diffraction patterns to be collected from much smaller crystals, or even single well ordered domains of large crystals composed of several small mosaic blocks, MicroED has the potential to overcome the limiting size requirement and enable structural studies on difficult-to-crystallize samples. This communication details the steps for sample preparation, data collection and reduction necessary to obtain refined, high-resolution, three-dimensional models by MicroED, and presents some of its unique challenges.

  14. 'Mystery shoppers' can uncover ED weaknesses.

    PubMed

    2006-12-01

    One veteran "mystery shopper" has uncovered several common ED practices that can hurt patient satisfaction. You can learn from her observations to improve your ED's customer service: Be sure to let all of your patients know how long they might expect to wait before seeing a doctor. Wash your hands where the patient can see you, so they can be confident you are practicing good hygiene. Clearly explain all forms and discharge instructions to help ensure patient compliance. PMID:17209484

  15. Non–Emergency Department (ED) Interventions to Reduce ED Utilization: A Systematic Review

    PubMed Central

    Morgan, Sofie Rahman; Chang, Anna Marie; Alqatari, Mahfood; Pines, Jesse M.

    2014-01-01

    Objectives Recent health policy changes have focused efforts on reducing emergency department (ED) visits as a way to reduce costs and improve quality of care. This was a systematic review of interventions based outside the ED aimed at reducing ED use. Methods This study was designed as a systematic review. We reviewed the literature on interventions in five categories: patient education, creation of additional non-ED capacity, managed care, prehospital diversion, and patient financial incentives. Studies written in English, with interventions administered outside of the ED, and a comparison group where ED use was an outcome, were included. Two independent reviewers screened search results using MEDLINE, Cochrane, OAIster, or Scopus. The following data were abstracted from included studies: type of intervention, study design, population, details of intervention, effect on ED use, effect on non-ED health care use, and other health and financial outcomes. Quality of individual articles was assessed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) guidelines. Results Of 39 included studies, 34 were observational and five were randomized controlled trials. Two of five studies on patient education found reductions in ED use ranging from 21% to 80%. Out of 10 studies of additional non-ED capacity, four showed decreases of 9% to 54%, and one a 21% increase. Both studies on prehospital diversion found reductions of 3% to 7%. Of 12 studies on managed care, 10 had decreases ranging from 1% to 46%. Nine out of 10 studies on patient financial incentives found decreases of 3% to 50%, and one a 34% increase. Nineteen studies reported effect on non-ED use with mixed results. Seventeen studies included data on health outcomes, but 13 of these only included data on hospitalizations rather than morbidity and mortality. Seven studies included data on cost outcomes. According to the GRADE guidelines, all studies had at least some risk of bias, with four

  16. Philadelphia chromosome-negative non-Hodgkin's lymphoma occurring in Philadelphia chromosome-positive chronic myeloid leukemia: A case report and literature review

    PubMed Central

    SHEN, ZHENG-LEI; YIN, LIE-FEN; MAO, WEN-WEN; LIANG, JIN; YANG, LING

    2016-01-01

    The current study reports the case of a patient with Philadelphia chromosome-negative (Ph−) non-Hodgkin's lymphoma (NHL) and chronic phase (CP) Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) that also possessed characteristic enlarged lymph nodes. A lymph node biopsy resulted in the diagnosis of CP-CML, in addition to T-lymphoblastic cell NHL with negative break point cluster/Abelson tyrosine kinase fusion genes in the lymph node of the patient, which was diagnosed as Ph− NHL. A review of the literature was performed in the present study to investigate the genetic differences between Ph− NHL and Ph+ NHL in patients with CML. The median age of patients with NHL and CML was 41 years. The follow-up time of patients with Ph+ NHL was significantly shorter (mean, <6 months) compared to the follow-up time of patients with Ph− NHL (mean, >15 months). Therefore the present study concludes that Ph+ NHL may be more aggressive compared with Ph+ NHL. The present study suggests that additional studies are required to assess the clinical and genetic characteristics of NHL patients with CML. PMID:27073575

  17. Spatial and Temporal Patterns in Cimex lectularius (Hemiptera: Cimicidae) Reporting in Philadelphia, PA

    PubMed Central

    MABUD, TARUB S.; BARBARIN, ALEXIS M.; BARBU, CORENTIN M.; LEVY, KATELYN H.; EDINGER, JASON; LEVY, MICHAEL Z.

    2014-01-01

    We analyzed a comprehensive telephone log of pest infestation reports to assess the spatial and temporal trends in Cimex lectularius L. (bed bug) reporting throughout Philadelphia, PA. Citywide spatial analyses of reports from September 2011 to June 2012 revealed several statistically significant bed bug hotspots. However, these were small and diffuse. Temporal analyses of reports from December 2008 to May 2011 detected prominent seasonality in bed bug reporting, peaking in August and reaching a nadir in February each year. Controlling for seasonal cycling, the number of bed bug reports in Philadelphia increased steadily at a rate of ≈4.5% per month (or 69.45% per year) from December 2008 to May 2011. While it may be difficult to spatially target citywide bed bug control measures because of the insects’ widespread migration, interventions informed by seasonal trends may enhance efforts to curb the recent increases in urban bed bug populations. PMID:24605452

  18. Update on the management of Philadelphia chromosome positive chronic myelogenous leukemia: role of nilotinib

    PubMed Central

    Emole, Josephine; Talabi, Taiwo; Pinilla-Ibarz, Javier

    2016-01-01

    Chronic myelogenous leukemia (CML) is a pluripotent stem cell disease characterized by the presence of the Philadelphia chromosome and the bcr-abl gene. The discovery of tyrosine kinase inhibitors (TKIs) revolutionized therapy for CML, such that durable response, increased overall survival, and increased progression-free survival of patients in chronic phase CML is now possible. Due to resistance and intolerance to imatinib, there was need for development of second- and third-generation TKIs for the treatment of CML. This review examines the role of nilotinib, an oral second-generation TKI, in the treatment of Philadelphia positive CML. The pharmacology, efficacy, and safety of nilotinib are critically evaluated. Patient-related issues, including tolerance, drug interactions, and quality of life issues are also examined. PMID:27013862

  19. Acute, fatal Sarcocystis calchasi-associated hepatitis in Roller pigeons (Columbia livia f. dom.) at Philadelphia Zoo

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Four Roller pigeons (Columba livia f. dom.) at the Philadelphia Zoo died suddenly. Necropsy examination revealed macroscopic hepatitis. Microscopically, the predominant lesions were in liver, characterized with necrosis and mixed cell inflammatory response. Sarcocystis calchasi-like schizonts and fr...

  20. Evaluation of the 2012 18th Maternal and Child Health (MCH) Epidemiology and 22nd CityMatCH MCH Urban Leadership Conference: six month impact on science, program, and policy.

    PubMed

    Arellano, Danielle E; Goodman, David A; Howlette, Travis; Kroelinger, Charlan D; Law, Mark; Phillips, Donna; Jones, Jessica; Brantley, Mary D; Fitzgerald, Maureen

    2014-09-01

    The 18th Maternal and Child Health (MCH) Epidemiology and 22nd CityMatCH MCH Urban Leadership Conference took place in December 2012, covering MCH science, program, and policy issues. Assessing the impact of the Conference on attendees' work 6 months post-Conference provides information critical to understanding the impact and the use of new partnerships, knowledge, and skills gained during the Conference. Evaluation assessments, which included collection of quantitative and qualitative data, were administered at two time points: at Conference registration and 6 months post-Conference. The evaluation files were merged using computer IP address, linking responses from each assessment. Percentages of attendees reporting Conference impacts were calculated from quantitative data, and common themes and supporting examples were identified from qualitative data. Online registration was completed by 650 individuals. Of registrants, 30 % responded to the 6 month post-Conference assessment. Between registration and 6 month post-Conference evaluation, the distribution of respondents did not significantly differ by organizational affiliation. In the 6 months following the Conference, 65 % of respondents reported pursuing a networking interaction; 96 % shared knowledge from the Conference with co-workers and others in their agency; and 74 % utilized knowledge from the Conference to translate data into public health action. The Conference produced far-reaching impacts among Conference attendees. The Conference served as a platform for networking, knowledge sharing, and attaining skills that advance the work of attendees, with the potential of impacting organizational and workforce capacity. Increasing capacity could improve MCH programs, policies, and services, ultimately impacting the health of women, infants, and children. PMID:25107597

  1. History of individuals of the 18th/19th centuries stored in bones, teeth, and hair analyzed by LA-ICP-MS--a step in attempts to confirm the authenticity of Mozart's skull.

    PubMed

    Stadlbauer, Christina; Reiter, Christian; Patzak, Beatrix; Stingeder, Gerhard; Prohaska, Thomas

    2007-06-01

    A cranium stored in the Stiftung Mozarteum in Salzburg/Austria which is believed to be that of Mozart, and skeletal remains of suspected relatives which have been excavated from the Mozart family grave in the cemetery in Salzburg, have been subjected to scientific investigations to determine whether or not the skull is authentic. A film project by the Austrian television ORF in collaboration with Interspot Film on this issue was broadcast at the beginning of the "Mozart year 2006". DNA analysis could not clarify relationships among the remains and, therefore, assignment of the samples was not really possible. In our work this skull and excavated skeletal remains have been quantified for Pb, Cr, Hg, As, and Sb content by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) to obtain information about the living conditions of these individuals. A small splinter of enamel (less than 1 mm(3)) from a tooth of the "Mozart cranium" was also available for investigation. Quantification was performed by using spiked hydroxyapatite standards. Single hair samples which are recorded to originate from Mozart have also been investigated by LA-ICP-MS and compared with hair samples of contemporary citizens stored in the Federal Pathologic-Anatomical Museum, Vienna. In general, Pb concentrations up to approximately 16 mug g(-1) were found in the bone samples of 18th century individuals (a factor of 7 to 8 higher than in recent samples) reflecting elevated Pb levels in food or beverages. Elevated Pb levels were also found in hair samples. The amount of Sb in the enamel sample of the "Mozart cranium" (approx. 3 mug g(-1)) was significantly higher than in all the other tooth samples investigated, indicating possible Sb ingestion in early childhood. Elevated concentrations of elements in single hair samples gave additional information about possible exposure of the individuals to heavy metals at a particular point in their life. PMID:17429616

  2. Seizing Opportunities: Genie Tyburski--Ballard Spahr Andrews & Ingersoll, LLP, Philadelphia

    ERIC Educational Resources Information Center

    Library Journal, 2004

    2004-01-01

    Genie Tyburski did not set out to be a law librarian. When asked at Drexel's library school what kind of librarian she wanted to be, she was surprised that "a good one" was not one of the options. But six weeks into the semester, she landed a part-time cataloging job at Community Legal Services in Philadelphia; six months later she was the library…

  3. The feasibility of refuse-fired energy generation in Philadelphia, Pennsylvania

    NASA Astrophysics Data System (ADS)

    Christman, W. M., III

    1982-02-01

    The City of Philadelphia presently disposes of 816, 480 megagrams per year (MGY) of residential refuse, with 1 megagram = 10 to the 3rd power hilograms. Alternatives to a base case of continued incineration and landfilling are evaluated. It is assured that the feasibility studies will yield compatible products and will run a uniform economic analysis against the base case, using as inputs the outputs of the feasibility analyses.

  4. ED Patients with Prolonged Complaints and Repeat ED Visits Have an Increased Risk of Depression

    PubMed Central

    Brickman, Kristopher R.; Bahl, Rajiv; Marcinkowski, Nathan F.; Ammons, Katelyn R.; Akpunonu, Peter

    2016-01-01

    Introduction The objective of this study was to explore associations between presenting chief complaints of prolonged symptomatology, patient usage of the emergency department (ED), and underlying depression so that emergency physicians may better target patients for depression screening. Methods A convenience sample of ED patients were administered the Beck Depression Inventory-II (BDI-II) to assess for depression. We correlated completed BDI-II surveys to patient information including demographics, pertinent history of present illness information, and past medical history. Results Out of 425 participants screened, we identified complaints of two weeks or longer in 92 patients (22%). Of these patients, mild to severe depression was recognized in over half of the population (47), yet only nine patients reported a prior depression diagnosis. These 92 patients also visited the ED three times as frequently as those patients with more acute complaints (p<0.001). Finally, our study showed that patients with mild to severe depression had three times as many ED visits compared to patients with minimal or no depression (p<0.001). Conclusion Patients with complaints of symptomatology two weeks or longer are more likely to have underlying depression when presenting to the ED. Patients with three or more ED visits within the past year also have a greater incidence of underlying depression. We found a strong correlation between complaints with symptomatology of two weeks or longer and multiple ED visits, in which underlying depression may have contributed to these patients’ ED visits. PMID:27625727

  5. A Quantitative Content Analysis of Mercer University MEd, EdS, and Doctoral Theses

    ERIC Educational Resources Information Center

    Randolph, Justus J.; Gaiek, Lura S.; White, Torian A.; Slappey, Lisa A.; Chastain, Andrea; Harris, Rose Prejean

    2010-01-01

    Quantitative content analysis of a body of research not only helps budding researchers understand the culture, language, and expectations of scholarship, it helps identify deficiencies and inform policy and practice. Because of these benefits, an analysis of a census of 980 Mercer University MEd, EdS, and doctoral theses was conducted. Each thesis…

  6. Using Multispectral Analysis in GIS to Model the Potential for Urban Agriculture in Philadelphia

    NASA Astrophysics Data System (ADS)

    Dmochowski, J. E.; Cooper, W. P.

    2010-12-01

    In the context of growing concerns about the international food system’s dependence on fossil fuels, soil degradation, climate change, and other diverse issues, a number of initiatives have arisen to develop and implement sustainable agricultural practices. Many seeking to reform the food system look to urban agriculture as a means to create localized, sustainable agricultural production, while simultaneously providing a locus for community building, encouraging better nutrition, and promoting the rebirth of depressed urban areas. The actual impact of such system, however, is not well understood, and many critics of urban agriculture regard its implementation as impractical and unrealistic. This project uses multispectral imagery from United States Department of Agriculture’s National Agricultural Imagery Program with a one-meter resolution to quantify the potential for increasing urban agriculture in an effort to create a sustainable food system in Philadelphia. Color infrared images are classified with a minimum distance algorithm in ArcGIS to generate baseline data on vegetative cover in Philadelphia. These data, in addition to mapping on the ground, form the basis of a model of land suitable for conversion to agriculture in Philadelphia, which will help address questions related to potential yields, workforce, and energy requirements. This research will help city planners, entrepreneurs, community leaders, and citizens understand how urban agriculture can contribute to creating a sustainable food system in a major North American city.

  7. MicroED data collection and processing

    PubMed Central

    Hattne, Johan; Reyes, Francis E.; Nannenga, Brent L.; Shi, Dan; de la Cruz, M. Jason; Leslie, Andrew G. W.; Gonen, Tamir

    2015-01-01

    MicroED, a method at the intersection of X-ray crystallography and electron cryo-microscopy, has rapidly progressed by exploiting advances in both fields and has already been successfully employed to determine the atomic structures of several proteins from sub-micron-sized, three-dimensional crystals. A major limiting factor in X-ray crystallography is the requirement for large and well ordered crystals. By permitting electron diffraction patterns to be collected from much smaller crystals, or even single well ordered domains of large crystals composed of several small mosaic blocks, MicroED has the potential to overcome the limiting size requirement and enable structural studies on difficult-to-crystallize samples. This communication details the steps for sample preparation, data collection and reduction necessary to obtain refined, high-resolution, three-dimensional models by MicroED, and presents some of its unique challenges. PMID:26131894

  8. One Year Medical Outcomes and ED Recidivism Following ED Observation for Cocaine-Associated Chest Pain

    PubMed Central

    Cunningham, Rebecca; Walton, Maureen A.; Weber, Jim Edward; O'Broin, Samantha; Tripathi, Shanti P; Maio, Ronald F.; Booth, Brenda M.

    2010-01-01

    Chest pain is the most common complaint among cocaine users who present to the ED seeking care and many hospital resources are applied to stratify cocaine users in regard to future cardiac morbidity and mortality. Little is known about the longitudinal cardiac and non cardiac medical outcomes of cocaine users who have been stratified to an ED observation period following their ED visit. Objectives to examine one-year cardiac outcomes in a low-intermediate risk sample of patients with cocaine- associated chest pain in an urban ED, as well as to examine ED recidivism one year for cardiac and non-cardiac complaints. Methods Prospective consecutive cohort study of patients (18–60 years) who presented to an urban Level 1 ED with cocaine-associated chest pain and were risk stratified to low-intermediate cardiac risk. Exclusion criteria: EKG suggestive of AMI, elevated serum cardiac markers, history of AMI or CABG, hemodynamic instability, unstable angina. Baseline interviews using validated measures of health functioning, and substance use were conducted during CPOU stay, and 3, 6, and 12 months. ED utilization during the study year was abstracted from medical chart. Zero-Inflated Poisson regression analyses were conducted to predict recurrent ED visits. Results 219 participants (73% participation) were enrolled, 65% returned to the ED post index visit; 23% returned for chest pain, of these 66% had a positive cocaine urine screen. No patient had an AMI within the one year follow up period. Patients with continued cocaine use were more likely to have a recurrent ED visit (p<0.001) but these repeat visits were most often related to musculoskeletal pain (21%), and injury (30%) rather than potential cardiac complaints. Conclusions Patients with cocaine-associated chest pain who are low to intermediate cardiac risk and complete a CPOU protocol have less then 1% rate of MI in the subsequent 12-months. PMID:18824277

  9. Improving ED efficiency to capture additional revenue.

    PubMed

    Mandavia, Sujal; Samaniego, Loretta

    2016-06-01

    An increase in the number of patients visiting emergency departments (EDs) presents an opportunity for additional revenue if hospitals take four steps to optimize resources: Streamline the patient pathway and reduce the amount of time each patient occupies a bed in the ED. Schedule staff according to the busy and light times for patient arrivals. Perform registration and triage bedside, reducing initial wait times. Create an area for patients to wait for test results so beds can be freed up for new arrivals. PMID:27451568

  10. Canadian EdGEO National Workshop Program

    NASA Astrophysics Data System (ADS)

    Clinton, L. A.; Haidl, F. M.; Hymers, L. A.; van der Flier-Keller, E.

    2009-05-01

    Established in the early 1970s, EdGEO supports locally driven geosciences workshops for Canadian teachers. Workshops are organized by geoscientists and teachers, and typically have field, laboratory and classroom components. Grants of up to $3000 per workshop are available from the National EdGEO Program. By providing educational opportunities for today's teachers and, through them, their students, EdGEO seeks to cultivate a heightened awareness of our planet. EdGEO workshops provide teachers with potential fieldtrip sites for their students and the knowledge, enthusiasm and materials to inspire their students to engage in geoscience. Networking opportunities with local experts promote the importance of the geoscience profession. The expected result is an improved capacity on the part of Canadians to understand the Earth and to make informed decisions, especially with regard to the use of mineral and energy resources, the maintenance and remediation of the environment, and response to geological hazards. There exists a critical need to provide teachers with training and resources to tackle their Earth science curricula. In 2008, EdGEO supported fourteen workshops, with an unprecedented 521 teachers attending. These teachers then used our resources to reach an estimated 14,000 students during that single academic year. EdGEO workshops are locally driven and are therefore very diverse. Workshops are strongly tied to the provincial curriculum, focus on a specific geoscience topic, or may be largely field-based to demonstrate and practice how field activities could be incorporated into Earth science teaching. Many strive to include all of these important components. Geoscientists and teachers work collaboratively to develop and deliver EdGEO workshops to ensure that the activities can be effectively used in the classroom. The length of these professional development opportunities range from two-hour sessions to several days, and can generally accommodate up to twenty

  11. ROBUST ESTIMATES OF THE ED50

    EPA Science Inventory

    To explore the possibility that robust estimators of location can be adapted to the problem of estimating the ED50 in binary-response bioassay, 10 estimators are compared. A Monte Carlo study is conducted to determine the mean squared errors (MSE) of the estimators. Taking into a...

  12. The Trouble with the Ed.D

    ERIC Educational Resources Information Center

    Flessa, Joseph

    2007-01-01

    This article review examines Arthur Levine's 2005 "Educating School Leaders," a report that recommended the elimination of the Ed.D. and the establishment of a new degree, the Master's in Educational Administration. The article review draws attention to the central irony of Levine's report: after chronicling the many ways that schools of education…

  13. The Consequences of edTPA

    ERIC Educational Resources Information Center

    Greenblatt, Deborah

    2016-01-01

    States and teacher preparation programs across the country are increasingly using a teacher candidate assessment called edTPA. The purpose? To make sure that teacher candidates are ready and able to teach before they begin their careers. The teacher performance assessment requires candidates to compile a portfolio that consists of lesson plans,…

  14. 5. Photocopy of 1963 photograph showing parlor in the center ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopy of 1963 photograph showing parlor in the center (18th century) section of the mansion. Original photograph at the Philadelphia Museum of Art. - Strawberry Mansion, Philadelphia, Philadelphia County, PA

  15. Neighborhood racial composition, social capital and black all-cause mortality in Philadelphia.

    PubMed

    Hutchinson, Rebbeca N; Putt, Mary A; Dean, Lorraine T; Long, Judith A; Montagnet, Chantal A; Armstrong, Katrina

    2009-05-01

    Neighborhood characteristics such as racial composition and social capital have been widely linked to health outcomes, but the direction of the relationship between these characteristics and health of minority populations is controversial. Given this uncertainty, we examined the relationship between neighborhood racial composition, social capital, and black all-cause mortality between 1997 and 2000 in 68 Philadelphia neighborhoods. Data from the U.S. Census, the Philadelphia Health Management Corporation's 2004 Southeast Pennsylvania Community Health Survey, and city vital statistics were linked by census tract and then aggregated into neighborhoods, which served as the unit of analysis. Neighborhood social capital was measured by a summative score of respondent assessments of: the livability of their community, the likelihood of neighbors helping one another, their sense of belonging, and the trustworthiness of their neighbors. After adjustment for the sociodemographic characteristics of neighborhood residents, black age-adjusted all-cause mortality was significantly higher in neighborhoods that had lower proportion of black residents. Neighborhood social capital was also associated with lower black mortality, with the strongest relationship seen for neighborhoods in the top half of social capital scores. There was a significant interaction between racial composition and social capital, so that the effect of social capital on mortality was greatest in neighborhoods with a higher proportion of black residents and the effect of racial composition was greatest in neighborhoods with high social capital. These results demonstrate that age-adjusted all-cause black mortality is lowest in mostly black neighborhoods with high levels of social capital in Philadelphia. PMID:19324485

  16. Phylogenetic Reconstruction of the Legionella pneumophila Philadelphia-1 Laboratory Strains through Comparative Genomics

    PubMed Central

    Ensminger, Alexander W.

    2013-01-01

    Over 20 years ago, two groups independently domesticated Legionella pneumophila from a clinical isolate of bacteria collected during the first recognized outbreak of Legionnaires’ disease (at the 1976 American Legion’s convention in Philadelphia). These two laboratory strains, JR32 and Lp01, along with their derivatives, have been disseminated to a number of laboratories around the world and form the cornerstone of much of the research conducted on this important pathogen to date. Nevertheless, no exhaustive examination of the genetic distance between these strains and their clinical progenitor has been performed thus far. Such information is of paramount importance for making sense of several phenotypic differences observed between these strains. As environmental replication of L. pneumophila is thought to exclusively occur within natural protozoan hosts, retrospective analysis of the domestication and axenic culture of the Philadelphia-1 progenitor strain by two independent groups also provides an excellent opportunity to uncover evidence of adaptation to the laboratory environment. To reconstruct the phylogenetic relationships between the common laboratory strains of L. pneumophila Philadelphia-1 and their clinical ancestor, we performed whole-genome Illumina resequencing of the two founders of each laboratory lineage: JR32 and Lp01. As expected from earlier, targeted studies, Lp01 and JR32 contain large deletions in the lvh and tra regions, respectively. By sequencing additional strains derived from Lp01 (Lp02 and Lp03), we retraced the phylogeny of these strains relative to their reported ancestor, thereby reconstructing the evolutionary dynamics of each laboratory lineage from genomic data. PMID:23717549

  17. Dioxin analysis of Philadelphia Northwest Incinerator. Summary report. Volume 2. Appendices A - F. Technical report

    SciTech Connect

    Neulicht, R.

    1985-10-31

    A study was conducted by US EPA Region 3 to determine the dioxin-related impact of the Philadelphia Northwest Incinerator on public health. Specifically, it was designed to assess quantitatively the risks to public health resulting from emissions into the ambient air of dioxins as well as the potential effect of deposition of dioxins on the soil in the vicinity of the incinerator. Volume 1 is an executive summary of the study findings. Volume 2 contains contractor reports, laboratory analysis results and other documentation.

  18. Evolving Therapeutic Strategies for the Classic Philadelphia-Negative Myeloproliferative Neoplasms

    PubMed Central

    Kaplan, Jason B.; Stein, Brady L.; McMahon, Brandon; Giles, Francis J.; Platanias, Leonidas C.

    2016-01-01

    Despite the emergence of JAK inhibitors, there is a need for disease-modifying treatments for Philadelphia-negative myeloproliferative neoplasms (MPNs). JAK inhibitors ameliorate symptoms and address splenomegaly, but because of the heterogeneous contributors to the disease process, JAK inhibitor monotherapy incompletely addresses the burden of disease. The ever-growing understanding of MPN pathogenesis has provided the rationale for testing novel and targeted therapeutic agents, as monotherapies or in combination, in preclinical and clinical settings. A number of intriguing options have emerged, and it is hoped that further progress will lead to significant changes in the natural history of MPNs. PMID:26870834

  19. Site handbook: data acquisition system information, passive solar retrofit Automobile Maintenance Facility, City of Philadelphia

    SciTech Connect

    Not Available

    1985-01-01

    Data were collected at the City of Philadelphia's Auto Maintenance Facility using an Aeoloan Kinetics PDL-24 data acquisition system. Instantaneous data readings were recorded each 15 seconds by the microprocessor. These channel readings were then averaged to produce hourly values which were then stored on an audio cassette. The energy saving strategies include: styrofoam and concrete roof coverings; weatherstripping; replacement of north windows with combination insulation and view glazing; PVC strips between heated and unheated areas; gas fired radiant heaters at individual work stations; reduction of the number of light fixtures; and the installation of retrofit window units for radiant solar heating, daylighting, ventilation, glare control and vandalism protection.

  20. Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia or Chronic Myeloid Leukemia in Lymphoid Blast Crisis.

    PubMed

    Kolenova, Alexandra; Maloney, Kelly W; Hunger, Stephen P

    2016-08-01

    The clinical characteristics of chronic myeloid leukemia (CML) in lymphoid blast crisis (BC) can resemble those of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph ALL). Because of this, there can be concern as to whether a patient with newly diagnosed Ph leukemia has Ph ALL or CML in lymphoid BC. This distinction has significant potential therapeutic implications because most children with Ph ALL are now treated with chemotherapy plus a tyrosine kinase inhibitor, whereas allogeneic stem cell transplant is usually recommended for any patient with CML that presents in or later develops BC. PMID:27164534

  1. Cytoplasmic Streaming - Skylab Student Experiment ED-63

    NASA Technical Reports Server (NTRS)

    1973-01-01

    This chart describes the Skylab student experiment (ED-63), Cytoplasmic Streaming, proposed by Cheryl A. Peitz of Arapahoe High School, Littleton, Colorado. Experiment ED-63 was to observe the effect of zero-gravity on cytoplasmic streaming in the aquatic plant named Elodea, commonly called water weed or water thyme. The phenomenon of cytoplasmic streaming is not well understood, but it is recognized as the circulation mechanism of the internal materials or cytoplasm of a cell. Cytoplasm is a gelatinous substance that has the ability to change its viscosity and flow, carrying various cell materials with it. The activity can be stimulated by sunlight or heat. In March 1972, NASA and the National Science Teachers Association selected 25 experiment proposals for flight on Skylab. Science advisors from the Marshall Space Flight Center aided and assisted the students in developing the proposals for flight on Skylab.

  2. Syncope risk stratification in the ED.

    PubMed

    Dipaola, Franca; Costantino, Giorgio; Solbiati, Monica; Barbic, Franca; Capitanio, Chiara; Tobaldini, Eleonora; Brunetta, Enrico; Zamunér, Antonio Roberto; Furlan, Raffaello

    2014-09-01

    Syncope may be the final common presentation of a number of clinical conditions spanning benign (i.e. neurally-mediated syncope) to life-threatening diseases (i.e. cardiac syncope). Hospitalization rate after a syncopal episode is high. An effective risk stratification is crucial to identify patients at risk of poor prognosis in the short term period to avoid unnecessary hospital admissions. The decision to admit or discharge a syncope patient from the ED is often based on the physician's clinical judgment. In recent years, several prognostic tools (i.e. clinical prediction rules and risk scores) have been developed to provide emergency physicians with accurate guidelines for hospital admission. At present, there are no compelling evidence that prognostic tools perform better than physician's clinical judgment in assessing the short-term outcome of syncope. However, the risk factors characterizing clinical prediction rules and risk scores may be profitably used by emergency doctors in their decision making, specifically whenever a syncope patient has to be discharged from ED or admitted to hospital. Patients with syncope of undetermined etiology, who are characterized by an intermediate-high risk profile after the initial evaluation, should be monitored in the ED. Indeed, data suggest that the 48h following syncope are at the highest risk for major adverse events. A new tool for syncope management is represented by the Syncope Unit in the ED or in an outpatient setting. Syncope Unit may reduce hospitalization and length of hospital stay. However, further studies are needed to clarify whether syncope patients' prognosis can be also improved. PMID:24811585

  3. Regional Energy Deployment System (ReEDS)

    SciTech Connect

    Short, W.; Sullivan, P.; Mai, T.; Mowers, M.; Uriarte, C.; Blair, N.; Heimiller, D.; Martinez, A.

    2011-12-01

    The Regional Energy Deployment System (ReEDS) is a deterministic optimization model of the deployment of electric power generation technologies and transmission infrastructure throughout the contiguous United States into the future. The model, developed by the National Renewable Energy Laboratory's Strategic Energy Analysis Center, is designed to analyze the critical energy issues in the electric sector, especially with respect to potential energy policies, such as clean energy and renewable energy standards or carbon restrictions. ReEDS provides a detailed treatment of electricity-generating and electrical storage technologies and specifically addresses a variety of issues related to renewable energy technologies, including accessibility and cost of transmission, regional quality of renewable resources, seasonal and diurnal generation profiles, variability of wind and solar power, and the influence of variability on the reliability of the electrical grid. ReEDS addresses these issues through a highly discretized regional structure, explicit statistical treatment of the variability in wind and solar output over time, and consideration of ancillary services' requirements and costs.

  4. Evolution of Interannual and Decadal/Interdecadal variability of the SPCZ since the late 18th century using a network of Fiji coral δ18O time-series

    NASA Astrophysics Data System (ADS)

    Dassie, E. P.; Linsley, B. K.; Correge, T.; Wu, H. C.; Lemley, G. M.; Cabioch, G.

    2012-12-01

    interannual and D/I coral δ18O variability from equatorial sites in the Pacific (e.g. Maiana). Collectively, our results from the SPCZ region reflect the validity of the coral δ18O composite to track regional climatic variability at both interannual and decadal/interdecadal timescales. From the late 18th century to the late 19th century the D/I band dominates the Fiji composite while the ENSO-band amplitude is relatively small. Starting around 1885, this tendency reverses and we observed a drastic decrease in the D/I signal amplitude, with its variance reduced by more than 50%, while the ENSO-band signal increases progressively in amplitude toward the present, reaching unprecedented values during the mid-20th century. This switch around 1885 A.D. is unique over the last 250 years and may correspond to a reorganization of Pacific-wide climate.

  5. The introduction of deaconess nurses at the German hospital of the city of Philadelphia in the 1880s.

    PubMed

    Schweikardt, Christoph

    2010-01-01

    In 1884, seven deaconesses from Iserlohn, Germany, came to the Philadelphia German Hospital to take over nursing care and hospital administration. This article deals with the preparation and implementation of deaconess rule at the German Hospital and conflicts during the tenure of the first two Sisters Superior, Marie Krueger (1826-1887) and Wanda von Oertzen (1845-1897). Recruitment of the deaconesses took place within a network of relations between German and American motherhouses. Before their arrival in Philadelphia, the benefactor of the German Hospital, John D. Lankenau (1817-1901), had committed himself to hospital rule by the Sister Superior. A Deaconess Committee was created to deal with the opposition of the Medical Board. Introducing deaconesses to the Philadelphia German Hospital led to a major change of medical personnel and allowed the hospital to develop a new corporate identity. PMID:20067089

  6. Health-hazard evaluation report HETA 88-207-2195, Northwest Incinerator, Philadelphia, Pennsylvania

    SciTech Connect

    Kinnes, G.M.; Bryant, C.J.

    1992-03-01

    In response to a request from the City of Philadelphia and the American Federation of State, County and Municipal Employees, District Council 33, Local 427, an evaluation was undertaken of possible hazardous working conditions at the Northwest Incinerator (SIC-4953), Philadelphia, Pennsylvania. Full shift personal breathing zone and general area air samples were analyzed for polychlorinated dibenzodioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), total dust, respirable dust, crystalline silica (14808607), and metals. Airborne concentrations of respirable nuisance dust were all well below the permissible exposure limits. Concentrations of PCDDs/PCDFs expressed as 2,3,7,8-tetrachloro-dibenzo-p-dioxin (1746016) (TCDD) equivalents ranged from 0.01 to 12.8 picograms per cubic meter. There was also significant lead (7439921) surface contamination in one wipe sample. The authors conclude that possible exposures to PCDDs/PCDFs via inhalation and from surface contamination did exist. The facility ceased operations immediately after the evaluation. The authors recommend measures to cut down on exposure should the site be reopened for use or remediation.

  7. Cannabis extract treatment for terminal acute lymphoblastic leukemia with a Philadelphia chromosome mutation.

    PubMed

    Singh, Yadvinder; Bali, Chamandeep

    2013-09-01

    Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells and is typically well treated with combination chemotherapy, with a remission state after 5 years of 94% in children and 30-40% in adults. To establish how aggressive the disease is, further chromosome testing is required to determine whether the cancer is myeloblastic and involves neutrophils, eosinophils or basophils, or lymphoblastic involving B or T lymphocytes. This case study is on a 14-year-old patient diagnosed with a very aggressive form of ALL (positive for the Philadelphia chromosome mutation). A standard bone marrow transplant, aggressive chemotherapy and radiation therapy were revoked, with treatment being deemed a failure after 34 months. Without any other solutions provided by conventional approaches aside from palliation, the family administered cannabinoid extracts orally to the patient. Cannabinoid resin extract is used as an effective treatment for ALL with a positive Philadelphia chromosome mutation and indications of dose-dependent disease control. The clinical observation in this study revealed a rapid dose-dependent correlation. PMID:24474921

  8. Why support a women's medical college? Philadelphia's early male medical pro-feminists.

    PubMed

    Peitzman, Steven J

    2003-01-01

    The male founders and early faculty of Philadelphia's Woman's Medical College were mostly abolitionist physicians, zealous moralists for whom medical feminism formed only one of the cherished causes they could "manfully" and righteously defend. Male faculty of the late nineteenth century comprised "self-made" men, mostly new specialists, for whom strict sexism probably seemed inconsistent with progressive medicine. For some of these physicians-obviously a small minority-defending medical women and breaking the barriers of fraternity could be consistent with "manly" responsibility. The outcome of the collaboration of women and the dissident men physicians in nineteenth-century Philadelphia amounted to another seeming paradox: the majority of the male medical profession, both locally and nationally, tyrannically hindered women's entry into the profession, yet medicine opened its doors in advance of law and the clergy; and where this first occurred, such as in the community centered on Woman's Medical College, a novel gender rearrangement arose based on collaboration and friendship. PMID:14523261

  9. EDS coal liquefaction process development. Phase V. EDS Consolidation Program: flushing and blowdown system design

    SciTech Connect

    1984-01-01

    The flushing and blowdown system of an EDS plant provides the means of removing viscous coal products and slurry streams from plant vessels and lines. In addition, it provides the flushing oil needed during normal operations for purging instruments in slurry service, for flushing slurry pump and slurry agitator seals, and for flushing slurry safety valve inlet lines. It contains a blowdown system for collecting material from washing operations, including the transport of the collected material to slop tankage. The rerun options for depleting the inventory of collected slop are a related aspect of the flushing and blowdown system design although specific equipment for handling slop is not part of the flushing and blowdown system facilities. This report documents the results of a study which evaluates the flushing and blowdown requirements for a commercial-scale EDS plant. The work was conducted as part of the EDS Consolidation Program. The design recommendations represent a consolidation of learnings accrued during previous phases of the EDS Project including results obtained from ECLP operations, from the ECLP Test Program, and from past EDS Study Design preparations. 1 reference, 4 figures, 2 tables.

  10. EFFECTS OF ETHANE DIMETHANESULFONATE (EDS) ON ADULT AND IMMATURE RABBIT LEYDIG CELLS: COMPARISON WITH EDS-TREATED RAT LEYDIG CELLS

    EPA Science Inventory

    Ethane-dimethanesulfonate (EDS) has been shown to selectively kill Leydig cells and depress testosterone production in adult rats. ecent study has shown that immature rat leydig cells are less sensitive to EDS exposure. here is evidence that the rabbit metabolizes EDS to methane ...

  11. EDS Coal Liquefaction Process Development. Phase V. Laboratory evaluation of the characteristics of EDS Illinois bottoms

    SciTech Connect

    Lao, T C; Levasseur, A A

    1984-02-01

    This interim report documents work carried out by Combustion Engineering, Inc. under a contract to Exxon Research and Engineering Company to develop a conceptual Hybrid Boiler design fueled by the vacuum distillation residue (vacuum bottoms) derived from Illinois No. 6 coal in the EDS Coal Liquefaction Process. This report was prepared by Combustion Engineering, Inc., and is the first of two reports on the predevelopment phase of the Hybrid Boiler program. This report covers the results of a laboratory investigation to assess the fuel and ash properties of EDS vacuum bottoms. The results of the laboratory testing reported here were used in conjunction with Combustion Engineering's design experience to predict fuel performance and to develop appropriate boiler design parameters. These boiler design parameters were used to prepare the engineering design study reported in EDS Interim Report FE-2893-113, the second of the two reports on the predevelopment phase of the Hybrid Boiler Program. 46 figures, 29 tables.

  12. ED navigators steer patients to appropriate providers.

    PubMed

    2012-03-01

    At Presbyterian Healthcare Services in Albuquerque, NM, emergency department navigators refer patients with minor ailments to primary care providers or urgent care centers. All patients are triaged by nurse in ED. - Appropriate patients are sent to the hospital's Lean Track area where they are evaluated by a physician or mid-level provider. - Patients who can safely be treated in 12-24 hours are referred to the navigator, who obtains an appointment for them with a primary care provider or urgent care center. PMID:22423392

  13. Seasonal abundance of organic molecular markers in urban particulate matter from Philadelphia, PA

    NASA Astrophysics Data System (ADS)

    Li, Min; McDow, Stephen R.; Tollerud, David J.; Mazurek, Monica A.

    Organic molecular markers were measured in airborne particulate matter (PM10) from the City of Philadelphia North Broad Street air quality monitoring site to identify the seasonal abundance of key tracer compounds together with their dominant sources. Daily PM10 samples were collected seasonally in 2000 for four 2-week periods (January, April, August, and October). The North Broad Street site is within a heavily populated location in Philadelphia, PA. A suite of 52 individual organic marker compounds was monitored in the PM10 samples. Molecular markers, homologous compound series, and nonpolar and polar organic compounds were detected at ng m -3 ambient concentrations using gas chromatography/ion trap mass spectrometry (GC/IT MS). Organic diacids (C 3-C 9) and monoacids (C 10-C 30) had seasonal mass concentrations ranging from 91.0 (winter) to 261.8 ng m -3 (summer). Total n-alkanes (C 25-C 33) ranged from 25.9 (spring) to 49.5 ng m -3 (fall), total PAHs from 2.1 ng m -3 (summer) to 4.1 ng m -3 (winter), and total hopanes ranged from 4.0 ng m -3 (winter) to 7.4 ng m -3 (fall). The molecular marker ambient mass concentrations were normalized by the annual average mass of PM10 elemental carbon (EC) for the central Philadelphia area. The ambient mass concentrations to EC and OC ratios ranged from 2.6×10 -3 for total PAHs to EC to 115.3×10 -3 for total n-alkanoic acids to EC, 0.5×10 -3 for total PAHs to OC to 23.8×10 -3 for total n-alkanoic acids to OC. Ambient concentrations of individual markers are similar to other reported levels for metropolitan Los Angeles, CA and Atlanta, GA. Seasonal and daily variations of marker compounds are consistent with motor vehicle exhaust, particularly in winter. Summer concentration patterns indicate the importance of secondary organic aerosol to the PM10 ambient mass.

  14. Passive damping in EDS maglev systems.

    SciTech Connect

    Rote, D. M.

    2002-05-03

    There continues to be strong interest in the subjects of damping and drag forces associated with electrodynamic suspension (EDS) systems. While electromagnetic drag forces resist the forward motion of a vehicle and therefore consume energy, damping forces control, at least in part, the response of the vehicle to disturbances. Ideally, one would like to reduce the drag forces as much as possible while retaining adequate damping forces to insure dynamic stability and satisfactory ride quality. These two goals turn out to be difficult to achieve in practice. It is well known that maglev systems tend to be intrinsically under damped. Consequently it is often necessary in a practical system design to enhance the damping passively or actively. For reasons of cost and simplicity, it is desirable to rely as much as possible on passive damping mechanisms. In this paper, rough estimates are made of the passive damping and drag forces caused by various mechanisms in EDS systems. No attention will be given to active control systems or secondary suspension systems which are obvious ways to augment passive damping mechanisms if the latter prove to be inadequate.

  15. 33 CFR 165.T05-0495 - Safety Zone, Sugar House Casino Fireworks Display, Delaware River; Philadelphia, PA.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... general safety zone regulations found in 33 CFR 165.23 apply to the safety zone created by this temporary... Fireworks Display, Delaware River; Philadelphia, PA. 165.T05-0495 Section 165.T05-0495 Navigation and... Areas Fifth Coast Guard District § 165.T05-0495 Safety Zone, Sugar House Casino Fireworks...

  16. Examination of the Philadelphia Geriatric Morale Scale as a Subjective Quality-of-Life Measure in Elderly Hong Kong Chinese

    ERIC Educational Resources Information Center

    Wong, Eric; Woo, Jean; Hui, Elsie; Ho, Suzanne C.

    2004-01-01

    Purpose: We examine the psychometric properties of the Philadelphia Geriatric Morale Scale (PGMS) in an elderly Chinese population in Hong Kong. Design and Methods: The study consisted of two cohorts: (a) 759 participants aged 70 years and older living in the community who were recruited as part of a territory-wide health survey and interviewed in…

  17. [Alternative fuel vehicles for clean cities]. Final report from the City of Philadelphia Managing Director`s Office

    SciTech Connect

    Hadalski, J.M.

    1995-09-30

    The City of Philadelphia was awarded a grant for the ``development of a Public Information Component for the Clean Cities Program involving alternative fuels usage within the city of Philadelphia and the surrounding counties in the Philadelphia region``. During the summer of 1993, it was felt that the public needed considerable information on the costs, benefits, emission data, conversion information, and infrastructure requirements. Embodied in the 1993 proposal was the notion that a model could be developed within some type of structure charged with the tasks of market introduction of alternative fuels in the Greater Philadelphia area in a concerted, comprehensive way. As originally envisioned, in executing this grant, the City had several objectives in mind. Among these were the following: the organizing of various media events to showcase alternative fuels usage; (2) to begin a networking process with fleet managers in the area; (3) to provide sources of information to fleet managers and others interested in, and concerned with the conversion to alternative fuels; (4) documentation on research and analysis associated with alternative fuels.

  18. Over 30 Years of Language-in-Education Policy and Planning: Potter Thomas Bilingual School in Philadelphia.

    ERIC Educational Resources Information Center

    Cahnmann, Melisa

    1998-01-01

    Changes in politics, the economy, demographics, and local leadership all led to the establishment of the Potter Thomas Bilingual School in Philadelphia in 1969. Describes the school's history; how it created, implemented, and sustained language policies within its personnel, curriculum, evaluation, and community policies; and present and future…

  19. Report on "Let There Be Light: Nonfiction for Today's Children," the 1991 Drexel/Philadelphia Library Annual Conference.

    ERIC Educational Resources Information Center

    Gniewek, Debra Lyman; And Others

    1991-01-01

    Includes four papers from the 1991 conference on nonfiction for children that was sponsored by Drexel University and the Free Library of Philadelphia. Topics discussed include writing books for children; research for illustrating children's books; and the winner of the 1991 Drexel Citation, Aliki Liacouras Brandenberg. (LRW)

  20. A POPULATION EXPOSURE MODEL FOR PARTICULATE MATTER: CASE STUDY RESULTS FOR PM 2.5 IN PHILADELPHIA, PA

    EPA Science Inventory

    A population exposure model for particulate matter (PM), called the Stochastic Human Exposure and Dose Simulation (SHEDS-PM) model, has been developed and applied in a case study of daily PM2.5 exposures for the population living in Philadelphia, PA. SHEDS-PM is a probabilisti...

  1. An Investigation of Philadelphia's Youth Aid Panel: A Community-Based Diversion Program for First-Time Youthful Offenders.

    ERIC Educational Resources Information Center

    Chernoff, Nina W.; Watson, Bernadine H.

    This report describes the Philadelphia Youth Aid Panel (YAP), an alternative approach to juvenile justice. YAPs, also known as Community Accountability Panels, evolved from 1950s legislation empowering panels of community members to handle low-level juvenile offenders. The Youth Aid Panel allows low-level juvenile offenders who have admitted their…

  2. Boosting Adolescent and Young Adult Literacy: An Examination of Literacy Teaching and Learning in Philadelphia's Accelerated High Schools

    ERIC Educational Resources Information Center

    Gold, Eva; Edmunds, Kimberly; Maluk, Holly; Reumann-Moore, Rebecca

    2011-01-01

    In 2010-11, the School District of Philadelphia (the District) operated thirteen accelerated high schools that served approximately 2,000 under-credited, over-age students. Each of the accelerated schools was managed by one of seven external providers, each with its own educational approach, and each with a contractual agreement with the…

  3. Correlates to Human Papillomavirus Vaccination Status and Willingness to Vaccinate in Low-Income Philadelphia High School Students

    ERIC Educational Resources Information Center

    Bass, Sarah B.; Leader, Amy; Shwarz, Michelle; Greener, Judith; Patterson, Freda

    2015-01-01

    Background: Little is known about the correlates of human papillomavirus (HPV) vaccination or willingness to be vaccinated in urban, minority adolescents. Methods: Using responses to the 2013 Youth Risk Behavior Survey in Philadelphia, a random sample of high schools provided weighted data representing 20,941 9th to 12th graders. Stratified by…

  4. Designing Interactive Courseware: Creating an Electronic Edition of the Notes of Debates in the Philadelphia Convention of 1787.

    ERIC Educational Resources Information Center

    Schick, James B. M.

    2002-01-01

    Describes the educational philosophy and decisions that shaped development of an electronic reader's edition of James Madison's notes on the debates of the Philadelphia Convention of 1787. Discusses the role of hypermedia in history instruction. %Illustrates and explains the design of the resource. (PAL)

  5. School District of Philadelphia Student Achievement as Related to 2008-2009 K-8 Teachers' Perceptions of Major Academic Indicators

    ERIC Educational Resources Information Center

    Mason-Dorman, Cheryl

    2013-01-01

    The School District of Philadelphia (SDP), established in 1818, is the eighth largest school district in the United States, with a student enrollment of 184,560 K-12 students. Like most of the other large urban school districts in the United States, its student population consists of more minority students than non-minority students. As the white…

  6. Acquisition Policy Planning and Litigation: Language Planning in the Context of "Y.S. v. District of Philadelphia."

    ERIC Educational Resources Information Center

    Skilton, Ellen E.

    1992-01-01

    This paper discusses language policy and educational practice in the context of a class action law suit filed on behalf of Asian students in Philadelphia concerning their linguistic and academic needs. It addresses both macro and micro perspectives in its discussion of litigation policy, acquisition policy planning, and Asian Americans in the…

  7. CIO of the Year 2006: Pat Renzulli--The School District of Philadelphia's Top Technology Officer Puts Students First

    ERIC Educational Resources Information Center

    Technology & Learning, 2006

    2006-01-01

    This article profiles Pat Renzulli, CIO for the School District of Philadelphia, who was selected as David Kearns CIO of the Year 2006. Among other accomplishments, she developed a process for principals to receive key performance indicators, lead the implementation of an instructional management system, rolled out a district-wide technology…

  8. Adult Learning and Technology in OECD Countries. Proceedings of a Round Table (Philadelphia, Pennsylvania, February 14-16, 1996).

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France). Centre for Educational Research and Innovation.

    This book, which is based on the papers presented by the various countries attending an international conference on technology and adult learning, contains 16 papers examining the use of technology in adult learning programs in the context of major institutional and economic change. The following papers are included: "A View from Philadelphia:…

  9. The Accountability System: Defining Responsibility for Student Achievement. Children Achieving: Philadelphia's Education Reform. Progress Report Series 1996-1997.

    ERIC Educational Resources Information Center

    Luhm, Theresa; Foley, Ellen; Corcoran, Tom

    This report explores issues related to accountability in the context of Children Achieving, the school reform effort of Philadelphia (Pennsylvania). The accountability system begins with content standards in English/language arts, mathematics, science, and the arts. The Stanford-9 Achievement Test has been designated to assess how students are…

  10. 40 CFR 52.2053 - The Motor Vehicle Emissions Budgets for the Pennsylvania Counties in the Philadelphia-Wilmington...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... following revised 2009 Motor Vehicle Emissions Budgets (MVEBs) for fine particulate matter (PM2.5) and nitrogen oxides (NOX) for the Pennsylvania Counties in the Philadelphia-Wilmington, PA-NJ-DE 1997 PM2.5...: Applicable geographic area Year Tons peryear NOX Tons peryear PM2.5 Pennsylvania Counties in the...

  11. 40 CFR 52.2053 - The Motor Vehicle Emissions Budgets for the Pennsylvania Counties in the Philadelphia-Wilmington...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... following revised 2009 Motor Vehicle Emissions Budgets (MVEBs) for fine particulate matter (PM2.5) and nitrogen oxides (NOX) for the Pennsylvania Counties in the Philadelphia-Wilmington, PA-NJ-DE 1997 PM2.5...: Applicable geographic area Year Tons peryear NOX Tons peryear PM2.5 Pennsylvania Counties in the...

  12. Text message program improves outcomes, decreases ED utilization among ED patients with poorly controlled diabetes.

    PubMed

    2014-02-01

    Diabetic patients who lack access to primary care tend to frequent the ED, often with complications from their disease that could have been prevented with proper management and education. To get around the problem of access, researchers tested an automated program that continuously delivered educational messaging via text to a group of patients who presented to the ED with poorly controlled diabetes. After six months, researchers noted improvements in Hb A1c levels, self-reported medication adherence, and ED utilization when compared with a control group. And the impact was particularly noteworthy among Latinos, according to the researchers. The text messaging program, dubbed TExT-Med, was developed by four physicians and two diabetes educators. The messages were delivered daily, and contained educational as well motivational content derived from the National Diabetes Education Program.There were also medication reminders, healthy living challenges, and trivia questions about diabetes. At six months, Hb A1c levels decreased by 1.05% in the intervention group, compared to 0.60% in the control group, and self-reported medication adherence improved from 4.5 to 5.4 (as measured on an 8 point scale) in the intervention group versus a decrease of 0.1 in the control group. During the six-month study period, 35.9% of patients in the intervention group presented to the ED for care, as compared to 51.6% of patients in the control group. PMID:24505864

  13. Circulating Cytokine Levels as Markers of Inflammation in Philadelphia Negative Myeloproliferative Neoplasms: Diagnostic and Prognostic Interest

    PubMed Central

    Mondet, Julie; Hussein, Kais; Mossuz, Pascal

    2015-01-01

    Cytokines are well known mediators of numerous physiological and pathological processes. They contribute to the regulation of normal hematopoiesis but increasing data suggest that they also have a clinical impact in some hematopoietic malignancies. In particular, there is evidence that cytokines are implicated in the functional symptoms of Philadelphia negative myeloproliferative neoplasms (Ph− MPNs), suggesting that evaluation of circulating levels of cytokines could be of clinical interest for the characterization of patients at the time of diagnosis and for disease prognosis. In this review, we present the current knowledge on alteration of circulating cytokine profiles in MPNs and their role in myelofibrosis pathogenesis. Phenotypic correlation, prognostic value of cytokines, and impact of JAK inhibitors are also discussed. PMID:26525644

  14. Health-hazard evaluation report HETA 86-356-1930, Social Security District Office, Philadelphia, Pennsylvania

    SciTech Connect

    Burr, G.A.; Kline, M.K.

    1988-09-01

    In response to a request from the manager of the District Office of the Social Security Administration, located in Philadelphia, Pennsylvania, an investigation was made of possible hazardous working conditions at that site. Employees had experienced headaches and nausea perhaps arising from cigarette smoke, kerosene, and gasoline fumes. There were times when both kerosene and gasoline were stored at a gas station next to the office building. Interior carbon dioxide (CO/sub 2/) levels ranged from 800 to 1000 parts per million. Carbon monoxide levels were negligible. Temperatures ranged from 72 to 77 degrees. Relative humidity ranged from 39 to 50%. The authors recommend that air flows and rates be adjusted, the ventilation system be cleaned and corrected, and the gas station alter its schedule. Other recommendations included making technical adjustments to some equipment and making a complaint system and safety manual available to the employees.

  15. Distribution and transport of trace substances in the Schuylkill River basin from Berne to Philadelphia, Pennsylvania

    USGS Publications Warehouse

    Stamer, John K.; Yorke, Thomas H.; Pederson, Gary L.

    1985-01-01

    During the period from October 1978 to March 1981, the U.S. Geological Survey assessed the river quality of the Schuylkill River basin in Pennsylvania from the headwaters to the Fairmount Dam at Philadelphia (river mile 8.4). The assessment focused on the distribution and transport of trace metals and organic substances (trace substances). Trace metals included were arsenic, beryllium, cadmium, copper, lead, mercury, nickel, and zinc; trace organic substances included organochlorine insecticides and polychlorinated biphenyls. In general, concentrations of trace substances in the streambed sediments were greater in the main stem of the Schuylkill River than in its tributaries and exceeded the background concentrations in the study area. Concentrations of most trace metals in the sediments were lowest in the Berne area (river mile 95) and highest in the urban-industrial area of Reading (river mile 76). Concentrations generally decreased from Reading downstream to Philadelphia (river mile 10.2). Concentrations of the organochlorine insecticides chlordane, DDT and its metabolites, and dieldrin generally increased gradually from Berne to Philadelphia. Average concentrations of trace metals in the main stem of the Schuylkill River in the sediment-sized fraction, less than 0.063 millimeters, were: zinc, 603 ?g/g (micrograms per gram); lead, 284 ?g/g; copper, 252 ?g/g; nickel, 119 ?g/g; chromium, 96 ?g/g; beryllium, 8.2 ?g/g; arsenic, 0.64 ?g/g; and mercury, 0.002 ?g/g. Average concentrations of trace organic substances in sediments of the main stem of the river were: polychlorinated biphenyls, 152 ?g/kg (micrograms per kilogram); chlordane, 24 ?g/kg; DDT and its metabolites, 18 ?g/kg; and dieldrin, 1.8 ?g/kg. The average annual transport of trace substances by the river was computed for chromium, copper, lead, nickel, and zinc. Concentrations of other trace substances in the sediment-water mixtures were generally undetectable. Of the trace metals, average annual transport

  16. Hospital organizational change and financial status: costs and outcomes of care in Philadelphia.

    PubMed

    Crawford, Albert G; Goldfarb, Neil; May, Reuel; Moyer, Kerry; Jones, Jayne; Nash, David B

    2002-01-01

    Two recent changes in Philadelphia-area hospital organizations are consolidation into systems and acquisition of 2 medical school hospitals by a for-profit chain. This study explored whether such consolidation and conversion affected costs and outcomes of care. The analysis included 1,617,581 discharges from 49 acute-care hospitals from 1997 to 1999. Analyses within and between medical school hospitals examined trends in discharges, case mix, length of stay, and mortality. The study addressed 2 questions: whether, as hospitals consolidate into medical school hospital-based systems, volume, severity, length of stay, and mortality increase in those hospitals; and whether for-profit conversion redistributes complex, high-cost admissions to nonprofit hospitals. The 2 medical school hospitals that became for-profit experienced decreases in volume and resource intensity, coupled at one with an increase in severity. However, these patterns were produced more by the system's financial instability than by consolidation or conversion. PMID:12487339

  17. University-assisted community school program of West Philadelphia: democratic partnerships that make a difference.

    PubMed

    Harkavy, Ira

    2005-01-01

    The university-assisted community school model is showing results for children and youth in West Philadelphia. The University of Pennsylvania's (Penn's) Center for Community Partnerships has coordinated universitywide efforts, in partnership with the community, in order to create and develop community school programs. The Sayre program aims to become a university-assisted community school, with a comprehensive community problem-solving curriculum and communitywide program that is fully integrated across both the Sayre curriculum and the curriculum of a number of Penn's schools. The Penn-Sayre project demonstrates that higher education can be a permanent anchor for revitalizing schools and communities if the vast resources it possesses, particularly its faculty, students, and staff, are brought to bear in a coordinated fashion. PMID:16315515

  18. STS-56 ESC Earth observation of metropolitan Philadelphia, PA at night

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-56 electronic still camera (ESC) Earth observation image shows metropolitan Philadelphia, Pennsylvania at night as recorded on the 48th orbit of Discovery, Orbiter Vehicle (OV) 103. The image was recorded with an image intensifier on the Hand-held, Earth-oriented, Real-time, Cooperative, User-friendly, Location-targeting and Environmental System (HERCULES). HERCULES is a device that makes it simple for shuttle crewmembers to take pictures of Earth as they merely point a modified 35mm camera and shoot any interesting feature, whose latitude and longitude are automatically determined in real-time. Center coordinates on this image are 39.970 degrees north latitude and 75.157 degrees west longitude. Digital file name is ESC04033.IMG.

  19. A case-crossover analysis of air pollution and mortality in Philadelphia.

    PubMed Central

    Neas, L M; Schwartz, J; Dockery, D

    1999-01-01

    This study reassessed Schwartz and Dockery's analysis of daily mortality from nonexternal causes among residents of Philadelphia, Pennsylvania, over 8 years, from 1973 to 1980 [American Review of Respiratory Disease 145:600-604 (1992)]. A Poisson regression analysis using the same model found that a 100-microg/m(3) increment in the 48-hr mean concentration of total suspended particulates (TSP) was associated with increased all-cause mortality [rate ratio = 1.069; 95% confidence interval (CI), 1.043-1.096) after adjustment for quadratic trend, season, year, previous day's mean temperature, dew point, winter temperature, and indicators of hot (temperature > 80 degrees F) and humid days (dew point > 66 degrees F). Critics suggested that time-varying factors such as season and day of week were not sufficiently controlled in this analysis and subsequent studies in other locations. We used a conditional logistic regression analysis with a case-crossover design to reanalyze the data, with air pollution in the prior and subsequent weeks to the day of death serving as referent periods. The case-crossover approach controls for season and day of week by design rather than modeling. We found that a 100-microg/m(3) increment in the 48-hr mean level of TSP was associated with increased all-cause mortality [odds ratio (OR) = 1.056; CI, 1.027-1.086) after adjustment for the same weather variables as above. Similar associations were observed for deaths in individuals over 65 years of age (OR = 1.074; CI, 1. 037-1.111) and for deaths due to cardiovascular disease (OR = 1.063; CI, 1.021-1.107). The current case-crossover analysis confirms the general conclusion of the previous Poisson regression analysis of an association of TSP with daily mortality in Philadelphia, Pennsylvania. PMID:10417359

  20. Familial translocation involving chromosomes 1 and 9 in a patient with Philadelphia-positive CML

    SciTech Connect

    Rehman, K.; Rosner, F.; Shanske, A.

    1994-09-01

    CML has provided a model for understanding the genetic basis of neoplasia. Approximately 5% of Philadelphia-positive patients have a variant chromosome rearrangement. We recently evaluated a patient with a previously unreported simple variant translocation that is part of a familial rearrangement. He had a constitutional translocation, t(1;9)(p21;p22), which was initially identified after his wife had a routine amniocentesis. Case report: K.H. was a 54-year-old male with CML for 4 years. He had been treated until recently with hydroxyurea. An abnormal male karyotype, 46,XY,t(1;9)(q21;p22),t(9;22)(q34;q11) was recorded from an unstimulated blood sample soon after diagnosis. Both translocations involved the same number 9 homologue resulting in a derivative 9(1pter{r_arrow}1q21::9p22{r_arrow}9q34::22q11{r_arrow}22qter). A recent CT scan of the chest showed a lytic lesion of a rib with associated soft tissue mass in the right costo-vertebral angle. He was hospitalized for progressive pain in the right lower chest and fever, treated for a UTI, required multiple transfusions for declining hemoglobin and platelets and died shortly thereafter. Autopsy revealed widespread chloromas as part of terminal CML. At least 13 complex rearrangements involving chromosomes 1, 9 and 22 are known. Our case represents a unique rearrangement with a familial component and also unique breakpoints for a Philadelphia variant. In line with the current view of cancer as a clonal disorder, perhaps the constitutional translocation contributed to the multi-step nature of the malignant transformation. In fact, a number of cancer-specific breakpoints in both regions of 1p and 9p are involved in the familial translocation.

  1. Capillary Study - Skylab Student Experiment ED-72

    NASA Technical Reports Server (NTRS)

    1973-01-01

    This chart describes the Skylab student experiment ED-72, Capillary Study, proposed by Roger G. Johnson of St. Paul, Mirnesota. Johnson theorized that capillary rise might continue to infinity in Skylab's zero-gravity environment. The behavior of fluids, particularly their flow properties in a low-gravity environment, had been important from the time that Robert H. Goddard launched his liquid-fueled rockets in the 1920's to the more sophisticated space systems of the day. It was necessary to design fluid-flow systems that would not only overcome the lack of gravity but also overcome, or take advantage of, the effect of surface tension. In March 1972, NASA and the National Science Teachers Association selected 25 experiment proposals for flight on Skylab. Science advisors from the Marshall Space Flight Center aided and assisted the students in developing the proposals for flight on Skylab.

  2. Contribution of ED admissions to inpatient hospital revenue.

    PubMed

    Sacchetti, Alfred; Harris, Russell H; Warden, Todd; Roth, Sandra

    2002-01-01

    Emergency department (ED) practices are traditionally profiled in terms of their patient encounters. Such evaluations reflect a preponderance of outpatient visits while crediting income from admitted patients to traditional hospital-based services. This study evaluates the contribution of ED admissions to inpatient hospital revenue. The study was set at an urban tertiary care community hospital with university affiliation. Information referable to ED patients was collected from the hospital's Universal Billing Code (UB-92)-based patient information warehouse. Data fields referable to hospital charges, insurance type, and disposition were used for analysis of a 1-year period from September 1, 1998 to August 31, 1999. Statistical analysis was through chi square and ANOVA. During the study period 33,174 patients were treated in the ED with 6,671 (20%) admitted to inpatient services. Total hospital charges for all ED patients during this time were $107 million dollars with $9.1 million (8.5%) generated from discharged patients and $98.0 million (91.5%) from admitted ED patients (P <.001). Mean charges for individual discharged patients were $344.10 whereas for individual admitted patients mean charges were $14,692.28. (P <.001) Medicaid and self pay represented 55.4% of the insurance coverage for discharged ED patients whereas these same insurance classes accounted for only 16.3% of admitted patients. (P <.001) Medicare visits accounted for 12.7% of discharged ED patients but 60.7% of admitted patients (P <.001). Total hospital gross revenue for inpatient services for the study period was $288 million of which 34% was contributed from admitted ED patients. ED services represent a major source of inpatient hospital revenue. The recognition of the ED's potential in this area may be lost if income from patients admitted through the ED is credited to traditional hospital-based services. PMID:11781909

  3. News Conference: Take a hold of Hands-on Science Meeting: Prize-winning physics-education talks are a highlight of the DPG spring meeting in Jena Event: Abstracts flow in for ICPE-EPEC 2013 Schools: A new Schools Physics Partnership in Oxfordshire Conference: 18th MPTL is forum for multimedia in education Meeting: Pursuing playful science with Science on Stage Forthcoming events

    NASA Astrophysics Data System (ADS)

    2013-03-01

    Conference: Take a hold of Hands-on Science Meeting: Prize-winning physics-education talks are a highlight of the DPG spring meeting in Jena Event: Abstracts flow in for ICPE-EPEC 2013 Schools: A new Schools Physics Partnership in Oxfordshire Conference: 18th MPTL is forum for multimedia in education Meeting: Pursuing playful science with Science on Stage Forthcoming events

  4. Could your ED meet a 15-minute service pledge?

    PubMed

    2003-01-01

    Patients dissatisfied with long waits is one of the most pressing problems that emergency department (ED) managers must address, and there is a trend of EDs offering service guarantees to patients to obtain higher satisfaction scores. At participating EDs, patients are offered letters of apology, movie passes, or a free visit if the guarantee isn't met. Census increased dramatically after the guarantee programs were implemented. To ensure the guarantees are met, additional nursing staff or ED beds may need to be added. PMID:12515111

  5. Success of Elective Cholecystectomy Treatment Plans After ED Visit

    PubMed Central

    Bingener, Juliane; Thomsen, Kristine M.; McConico, Andrea; Hess, Erik P.; Habermann, Elizabeth B.

    2014-01-01

    Introduction Differentiation between patients with acute cholecystitis and patients with severe biliary colic can be challenging. Patients with undiagnosed acute cholecystitis can incur repeat emergency department (ED) visits, which is resource intensive. Methods Billing records from 2000 – 2013 of all adults who visited the ED in the 30 days preceding their cholecystectomy were analyzed. Patients who were discharged from the ED and underwent elective cholecystectomy were compared to those who were discharged and returned to the ED within 30 days. T-tests, chi-square tests and multivariable analysis were utilized as appropriate. Results From 2000 - 2013, 3138 patients (34%) presented to the ED within 30 days prior to surgery, 63% were women, mean age 51 years, and of those 1625 were directly admitted from the ED for cholecystectomy while 1513 patients left the ED to return for an elective cholecystectomy. Patients who were discharged were younger (mean age 49 vs 54 yrs, p<0.001) and had shorter ED stays (5.9 vs 7.2 hrs, p<0.001) than the patients admitted immediately. Of the discharged patients, 303 (20%) returned to the ED within 30 days to undergo urgent cholecystectomy. Compared to patients with successful elective cholecystectomy after the ED visit, those who failed the pathway were more likely to have an ASA score > 3 and were <40 or ≥60 compared to the successful group. Conclusions One in five patients failed the elective cholecystectomy pathway after ED discharge, leading to additional patient distress and use of resources. Further risk factor assessment may help design efficient care pathways. PMID:25043530

  6. Simulation of ground-water flow in the Potomac-Raritan-Magothy aquifer system near the Defense Supply Center Philadelphia, and the Point Breeze Refinery, southern Philadelphia County, Pennsylvania

    USGS Publications Warehouse

    Schreffler, C.L.

    2001-01-01

    Ground-water flow in the Potomac-Raritan- Magothy aquifer system (PRM) in south Philadelphia and adjacent southwestern New Jersey was simulated by use of a three-dimensional, seven-layer finite-difference numerical flow model. The simulation was run from 1900, which was prior to groundwater development, through 1995 with 21 stress periods. The focus of the modeling was on a smaller area of concern in south Philadelphia in the vicinity of the Defense Supply Center Philadelphia (DSCP) and the Point Breeze Refinery (PBR). In order to adequately simulate the ground-water flow system in the area of concern, a much larger area was modeled that included parts of New Jersey where significant ground-water withdrawals, which affect water levels in southern Philadelphia, had occurred in the past. At issue in the area of concern is a hydrocarbon plume of unknown origin and time of release. The ground-water-flow system was simulated to estimate past water-level altitudes in and near the area of concern and to determine the effect of the Packer Avenue sewer, which lies south of the DSCP, on the ground-water-flow system. Simulated waterlevel altitudes for the lower sand unit of the PRM on the DSCP prior to 1945 ranged from pre-development, unstressed altitudes to 3 feet below sea level. Simulated water-level altitudes for the lower sand unit ranged from 3 to 7 feet below sea level from 1946 to 1954, from 6 to 10 feet below sea level from 1955 to 1968, and from 9 to 11 feet below sea level from 1969 to 1978. The lowest simulated water-level altitude on the DSCP was 10.69 feet below sea level near the end of 1974. Model simulations indicate ground water was infiltrating the Packer Avenue sewer prior to approximately 1947 or 1948. Subsequent to that time, simulated ground-water-level altitudes were lower than the bottom of the sewer.

  7. Urban sustainable energy development: A case study of the city of Philadelphia

    NASA Astrophysics Data System (ADS)

    Argyriou, Iraklis

    This study explores the role of cities in sustainable energy development through a governance-informed analysis. Despite the leading position of municipalities in energy sustainability, cities have been mostly conceptualized as sites where energy development is shaped by external policy scales, i.e. the national level. A growing body of research, however, critiques this analytical perspective, and seeks to better understand the type of factors and dynamics that influence energy sustainability within a multi-level policy context for urban energy. Given that particular circumstances are applicable across cities, a context-specific analysis can provide insight regarding how sustainable energy development takes place in urban areas. In applying such an analytical perspective on urban energy sustainability, this study undertakes a qualitative case study analysis for the city of Philadelphia, Pennsylvania, by looking at four key local policy initiatives relevant to building energy efficiency and solar electricity development at the municipal government and city-wide level. The evaluation of the initiatives suggests that renewable electricity use has increased substantially in the city over the last years but the installed capacity of local renewable electricity systems, including solar photovoltaics, is low. On the other hand, although the city has made little progress in meeting its building energy efficiency targets, more comprehensive action is taken in this area. The study finds that the above outcomes have been shaped mainly by four factors. The first is the city government's incremental policy approach aiming to develop a facilitative context for local action. The second is the role that a diverse set of stakeholders have in local sustainable energy development. The third is the constraints that systemic policy barriers create for solar power development. The fourth is the ways through which the relevant multi-level policy environment structures the city

  8. MedEdPORTAL: Educational Scholarship for Teaching

    ERIC Educational Resources Information Center

    Reynolds, Robby J.; Candler, Christopher S.

    2008-01-01

    MedEdPORTAL is an online publication service provided at no charge by the Association of American Medical Colleges (AAMC). The intent is to promote collaboration and educational scholarship by helping educators publish and share educational resources. With MedEdPORTAL, users can quickly locate high-quality, peer-reviewed teaching materials in both…

  9. Teaching Elementary School Social Studies Methods under edTPA

    ERIC Educational Resources Information Center

    An, Sohyun

    2016-01-01

    This article reports a self-study that analyzes my experience as a teacher educator navigating a turbulent educational landscape with the advent of edTPA. The data consist of my journal entries, the syllabi, handouts, work submitted by my students, and course evaluations. Data were analyzed by using an inductive process to describe how the edTPA…

  10. ExpandED Options: Learning beyond High School Walls

    ERIC Educational Resources Information Center

    ExpandED Schools, 2014

    2014-01-01

    Through ExpandED Options by TASC, New York City high school students get academic credit for learning career-related skills that lead to paid summer jobs. Too many high school students--including those most likely to drop out--are bored or see classroom learning as irrelevant. ExpandED Options students live the connection between mastering new…

  11. Web Formation - Skylab Student Experiment ED-52

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Judith S. Miles of Lexington High School, Lexington, Massachusetts, proposed skylab student experiment ED-52, Web Formation. This experiment was a study of a spider's behavior in a weightless environment. The geometrical structure of the web of the orb-weaving spider provides a good measure of the condition of its central nervous system. Since the spider senses its own weight to determine the required thickness of web material and uses both the wind and gravity to initiate construction of its web, the lack of gravitational force in Skylab provided a new and different stimulus to the spider's behavioral response. Two common cross spiders, Arabella and Anita, were used for the experiment aboard the Skylab-3 mission. After initial disoriented attempts, both spiders produced almost Earth-like webs once they had adapted to weightlessness. This photograph is of Arabella, a cross spider, in her initial attempt at spirning a web. This picture was taken by the crew of the Skylab 3 mission before Arabella adapted to her new environment.

  12. TechEdSat Nano-Satellite Series Fact Sheet

    NASA Technical Reports Server (NTRS)

    Murbach, Marcus; Martinez, Andres; Guarneros Luna, Ali

    2014-01-01

    TechEdSat-3p is the second generation in the TechEdSat-X series. The TechEdSat Series uses the CubeSat standards established by the California Polytechnic State University Cal Poly), San Luis Obispo. With typical blocks being constructed from 1-unit (1U 10x10x10 cm) increments, the TechEdSat-3p has a 3U volume with a 30 cm length. The project uniquely pairs advanced university students with NASA researchers in a rapid design-to-flight experience lasting 1-2 semesters.The TechEdSat Nano-Satellite Series provides a rapid platform for testing technologies for future NASA Earth and planetary missions, as well as providing students with an early exposure to flight hardware development and management.

  13. Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia

    ClinicalTrials.gov

    2015-10-29

    B-cell Adult Acute Lymphoblastic Leukemia; Blastic Phase Chronic Myelogenous Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia; Untreated Adult Acute Lymphoblastic Leukemia

  14. Superfund record of decision (EPA Region 3): Publicker Industries, Inc., operable unit 3, Philadelphia, PA, December 28, 1995

    SciTech Connect

    1997-04-01

    This decision document presents the selected remedial action for Operable Unit No. 3 of the Publicker Industries Site (the Site) in Philadelphia, Pennsyvlania. The major components of the selected remedy include: Abandonment of on-Site ground water wells; Removal, treatment, and off-Site disposal of liquids and sediments in contaminated electric utilities; Removal, treatment and off-Site disposal of liquids and sediments in contaminated stormwater trenches and utilities; and Removal treatment and off-Site disposal of miscellaneous wastes.

  15. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells.

    PubMed

    Karvela, Maria; Baquero, Pablo; Kuntz, Elodie M; Mukhopadhyay, Arunima; Mitchell, Rebecca; Allan, Elaine K; Chan, Edmond; Kranc, Kamil R; Calabretta, Bruno; Salomoni, Paolo; Gottlieb, Eyal; Holyoake, Tessa L; Helgason, G Vignir

    2016-06-01

    A major drawback of tyrosine kinase inhibitor (TKI) treatment in chronic myeloid leukemia (CML) is that primitive CML cells are able to survive TKI-mediated BCR-ABL inhibition, leading to disease persistence in patients. Investigation of strategies aiming to inhibit alternative survival pathways in CML is therefore critical. We have previously shown that a nonspecific pharmacological inhibition of autophagy potentiates TKI-induced death in Philadelphia chromosome-positive cells. Here we provide further understanding of how specific and pharmacological autophagy inhibition affects nonmitochondrial and mitochondrial energy metabolism and reactive oxygen species (ROS)-mediated differentiation of CML cells and highlight ATG7 (a critical component of the LC3 conjugation system) as a potential specific therapeutic target. By combining extra- and intracellular steady state metabolite measurements by liquid chromatography-mass spectrometry with metabolic flux assays using labeled glucose and functional assays, we demonstrate that knockdown of ATG7 results in decreased glycolysis and increased flux of labeled carbons through the mitochondrial tricarboxylic acid cycle. This leads to increased oxidative phosphorylation and mitochondrial ROS accumulation. Furthermore, following ROS accumulation, CML cells, including primary CML CD34(+) progenitor cells, differentiate toward the erythroid lineage. Finally, ATG7 knockdown sensitizes CML progenitor cells to TKI-induced death, without affecting survival of normal cells, suggesting that specific inhibitors of ATG7 in combination with TKI would provide a novel therapeutic approach for CML patients exhibiting persistent disease. PMID:27168493

  16. A comparison of acid aerosol and ozone exposure patterns in a summertime study of metropolitan Philadelphia

    SciTech Connect

    Waldman, J.M.; Liang, C.S.K.; Koutrakis, P.; Suh, H.; Allen, G.; Burton, R.; Wilson, W.E.

    1994-12-31

    A study of acid aerosol and ozone exposure patterns was conducted for metropolitan Philadelphia between June and August 1992. Included in the study design were daily monitoring of particulate strong acidity (PSA), sulfate (SO{sub 4}{sup {minus}2}) and hourly ozone data (O{sub 3}) at a citywide network. A continuous sulfate thermal speciation analyzer at one site collected hourly concentration data for SO{sub 4}{sup {minus}2} aerosol. The current paper presents temporal patterns of continuous measurements for O{sub 3} and SO{sub 4}{sup {minus}2} aerosol. Both pollutants had similar daily peak periods in the mid-afternoon, although the range for O{sub 3} was much greater than for SO{sub 4}{sup {minus}2} aerosol. The daily peak values were also correlated for the two species during the study period. It seems that many of the same meteorological factors affect the spatial and temporal patterns for these lung irritants. Hence, the similarity in exposure patterns for O{sub 3} and SO{sub 4}{sup {minus}2} aerosol is reason for concern, regarding possible synergism from coincident doses.

  17. Clinical features of patients with Philadelphia-negative myeloproliferative neoplasms complicated by portal hypertension

    PubMed Central

    Yan, Matthew; Geyer, Holly; Mesa, Ruben; Atallah, Ehab; Callum, Jeannie; Bartoszko, Justyna; Yee, Karen; Maganti, Manjula; Wong, Florence; Gupta, Vikas

    2015-01-01

    Backgroud Portal hypertension (PHTN) has been reported to afflict 7-18% of patients with Philadelphia-negative myeloproliferative neoplasms (MPNs), with complications of variceal bleeding and ascites. The clinical features and outcomes of these patients are unclear. Patients and Methods In this multi-centre retrospective study, we evaluated the clinical features of 51 patients with MPNs complicated by PHTN. Results The diagnosis of underlying MPN was most frequently polycythemia vera (PV) (39%) and primary myelofibrosis (MF) (35%), followed by post-PV myelofibrosis (18%), essential thrombocythemia (ET) (4%) and post-ET myelofibrosis (4%). Frequency of JAK2 V617F mutation appears as expected in the underlying MPN. Thrombosis within the splanchnic circulation was prevalent in patients with polycythemia compared to other MPNs (76% vs. 26%, p=0.0007). Conclusions PV and MF patients have a higher incidence of PHTN in our population, with thrombosis contributing to PHTN development in PV patients. Patients with splanchnic circulation thrombosis are potential candidates for screening for portal hypertension. These data may be useful for developing screening strategies for early detection of PHTN in patients with MPN. PMID:25027569

  18. Abrupt evolution of Philadelphia chromosome-positive acute myeloid leukemia in myelodysplastic syndrome.

    PubMed

    Fukunaga, Akiko; Sakoda, Hiroto; Iwamoto, Yoshihiro; Inano, Shojiro; Sueki, Yuki; Yanagida, Soshi; Arima, Nobuyoshi

    2013-03-01

    Myelodysplastic syndrome (MDS) is a clonal disorder arising from an alteration in multipotent stem cells, which lose the ability of normal proliferation and differentiation. Disease progression occurs in approximately 30% MDS cases. Specific chromosomal alterations seem responsible for each step in the evolution of acute myeloid leukemia (AML). Multiple genetic aberrations occur during the clonal evolution of MDS; however, few studies report the presence of the Philadelphia (Ph) chromosome. We report a rare case of Ph-positive AML, which evolved during the course of low-risk MDS. The patient, a 76-year-old man with mild leukocytopenia, was diagnosed with MDS, refractory neutropenia (RN). After 1.5 yr, his peripheral blood and bone marrow were suddenly occupied by immature basophils and myeloblasts, indicating the onset of AML. A bone marrow smear showed multilineage dysplasia, consistent with MDS evolution. Chromosomal analysis showed an additional t(9;22)(q34;q11) translocation. Because progression occurred concurrently with emergence of the Ph chromosome, we diagnosed this case as Ph-positive AML with basophilia arising from the clonal evolution of MDS. The patient was initially treated with nilotinib. A hematological response was soon achieved with disappearance of the Ph chromosome in the bone marrow. Emergence of Ph-positive AML in the course of low-risk MDS has rarely been reported. We report this case as a rare clinical course of MDS. PMID:23240925

  19. Creating a business environment in inventory management - The Philadelphia Electric Company experiences

    SciTech Connect

    Franks, A.J.; Birch, H. )

    1992-01-01

    Philadelphia Electric Company's (PECo's) Nuclear Engineering and Services Department was asked to develop a (non-fuel) inventory management philosophy that will optimize inventory dollars at Peach Bottom atomic power station and Limerick generating station. The ultimate goal of the project is to maximize the potential for the correct parts being available at the lowest possible level of investment. There are many factors that make the management of maintenance, repair, and operating (MRO) supply inventories more complicated than managing finished goods, work-in-progress, or raw materials. Determining correct inventory levels for nuclear power plants is complicated by the irregular demand for spare parts and the cyclic nature of demand caused by refueling outages. Based on the information collected, it was determined that PECo's nuclear group needed to develop policies and strategies to address the following issues: (1) inventory classification based on part criticality, usage, and demand forecast; (2) item level ordering policies based on classification system; (3) inventory performance management; and (4) management of obsolete/surplus parts. Currently, policies are being developed to manage surplus and obsolete materials. Opportunities are being explored regarding the potential capitalization of critical components and parts. The policies established for classification, ordering policies, and performance management are being translated into work processes via common procedures and guidelines.

  20. The Philadelphia Brief Assessment of Cognition (PBAC): A Validated Screening Measure for Dementia

    PubMed Central

    Libon, David J.; Rascovsky, Katya; Gross, Rachel G.; White, Matthew T.; Xie, Sharon X.; Dreyfuss, Michael; Boller, Ashley; Massimo, Lauren; Moore, Peachie; Kitain, Jessica; Coslett, H. Branch; Chatterjee, Anjan; Grossman, Murray

    2012-01-01

    The Philadelphia Brief Assessment of the Cognition (PBAC) is a brief dementia-screening instrument. The PBAC assesses five cognitive domains: working memory/executive control; lexical retrieval/language; visuospatial/visuoconstructional operations; verbal/visual episodic memory; and behavior/social comportment. A revised version of the PBAC was administered to 198 participants including patients with Alzheimer’s disease (AD) (n=46) and four groups of patients with frontotemporal dementia (FTD) syndromes: behavioral-variant FTD (bvFTD; n=65), semantic-variant primary progressive aphasia (PPA) (svPPA; n=22), non-fluent/agrammatic-variant PPA (nfaPPA; n=23), and corticobasal syndrome (CBS; n=42), and a group of normal controls (n=15). The total PBAC score was highly correlated with the MMSE. The criterion validity of the PBAC was assessed relative to standard neuropsychological test performance. Using standard neuropsychological test performance as a criterion, the total PBAC score accurately identified the presence and severity of dementia. Intra-class correlations between PBAC subscales and standard neuropsychological tests were highly significant. PBAC subscales demonstrated good clinical utility in distinguishing AD and FTD subtypes using receiver operating characteristic analysis and standard diagnostic performance statistics to determine optimal subscale cut scores. The PBAC is a valid tool and able to assesses differential patterns neuropsychological/behavioral impairment in a broad range of neurodegenerative conditions. PMID:22084867

  1. The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort

    PubMed Central

    Robinson, Elise B.; Kirby, Andrew; Ruparel, Kosha; Yang, Jian; McGrath, Lauren; Anttila, Verneri; Neale, Benjamin M.; Merikangas, Kathleen; Lehner, Thomas; Sleiman, Patrick M.A.; Daly, Mark J.; Gur, Ruben; Gur, Raquel; Hakonarson, Hakon

    2014-01-01

    The objective of this analysis was to examine the genetic architecture of diverse cognitive abilities in children and adolescents, including the magnitude of common genetic effects and patterns of shared and unique genetic influences. Subjects included 3,689 members of the Philadelphia Neurodevelopmental Cohort, a general population sample of ages 8-21 years who completed an extensive battery of cognitive tests. We used genome-wide complex trait analysis (GCTA) to estimate the SNP-based heritability of each domain, as well as the genetic correlation between all domains that showed significant genetic influence. Several of the individual domains suggested strong influence of common genetic variants (e.g. reading ability, h2g=0.43, p=4e-06; emotion identification, h2g=0.36, p=1e-05; verbal memory, h2g=0.24, p=0.005). The genetic correlations highlighted trait domains that are candidates for joint interrogation in future genetic studies (e.g. language reasoning and spatial reasoning, r(g)=0.72, p=0.007). These results can be used to structure future genetic and neuropsychiatric investigations of diverse cognitive abilities. PMID:25023143

  2. The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort.

    PubMed

    Robinson, E B; Kirby, A; Ruparel, K; Yang, J; McGrath, L; Anttila, V; Neale, B M; Merikangas, K; Lehner, T; Sleiman, P M A; Daly, M J; Gur, R; Gur, R; Hakonarson, H

    2015-04-01

    The objective of this analysis was to examine the genetic architecture of diverse cognitive abilities in children and adolescents, including the magnitude of common genetic effects and patterns of shared and unique genetic influences. Subjects included 3689 members of the Philadelphia Neurodevelopmental Cohort, a general population sample comprising those aged 8-21 years who completed an extensive battery of cognitive tests. We used genome-wide complex trait analysis to estimate the SNP-based heritability of each domain, as well as the genetic correlation between all domains that showed significant genetic influence. Several of the individual domains suggested strong influence of common genetic variants (for example, reading ability, h(2)g=0.43, P=4e-06; emotion identification, h(2)g=0.36, P=1e-05; verbal memory, h(2)g=0.24, P=0.005). The genetic correlations highlighted trait domains that are candidates for joint interrogation in future genetic studies (for example, language reasoning and spatial reasoning, r(g)=0.72, P=0.007). These results can be used to structure future genetic and neuropsychiatric investigations of diverse cognitive abilities. PMID:25023143

  3. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells

    PubMed Central

    Karvela, Maria; Baquero, Pablo; Kuntz, Elodie M.; Mukhopadhyay, Arunima; Mitchell, Rebecca; Allan, Elaine K.; Chan, Edmond; Kranc, Kamil R.; Calabretta, Bruno; Salomoni, Paolo; Gottlieb, Eyal; Holyoake, Tessa L.; Helgason, G. Vignir

    2016-01-01

    ABSTRACT A major drawback of tyrosine kinase inhibitor (TKI) treatment in chronic myeloid leukemia (CML) is that primitive CML cells are able to survive TKI-mediated BCR-ABL inhibition, leading to disease persistence in patients. Investigation of strategies aiming to inhibit alternative survival pathways in CML is therefore critical. We have previously shown that a nonspecific pharmacological inhibition of autophagy potentiates TKI-induced death in Philadelphia chromosome-positive cells. Here we provide further understanding of how specific and pharmacological autophagy inhibition affects nonmitochondrial and mitochondrial energy metabolism and reactive oxygen species (ROS)-mediated differentiation of CML cells and highlight ATG7 (a critical component of the LC3 conjugation system) as a potential specific therapeutic target. By combining extra- and intracellular steady state metabolite measurements by liquid chromatography-mass spectrometry with metabolic flux assays using labeled glucose and functional assays, we demonstrate that knockdown of ATG7 results in decreased glycolysis and increased flux of labeled carbons through the mitochondrial tricarboxylic acid cycle. This leads to increased oxidative phosphorylation and mitochondrial ROS accumulation. Furthermore, following ROS accumulation, CML cells, including primary CML CD34+ progenitor cells, differentiate toward the erythroid lineage. Finally, ATG7 knockdown sensitizes CML progenitor cells to TKI-induced death, without affecting survival of normal cells, suggesting that specific inhibitors of ATG7 in combination with TKI would provide a novel therapeutic approach for CML patients exhibiting persistent disease. PMID:27168493

  4. 56th and Walnut: A Philly Gut Rehab Development; Philadelphia, Pennsylvania (Fact Sheet)

    SciTech Connect

    Not Available

    2013-11-01

    Load-bearing brick-masonry multifamily buildings are prevalent in urban areas across much of the Northeast and mid-Atlantic. In most instances, these buildings are un-insulated unless they have been renovated within the past two decades. Affordable housing capital budgets typically limit what can be spent and energy improvements often take a back seat to basic capital improvements such as interior finish upgrades and basic repairs. The Consortium for Advanced Residential Buildings (CARB) is researching cost effective solution packages for significant energy efficiency and indoor air-quality improvements in these urban buildings. To explore how these low-cost retrofits can effectively integrate energy efficiency upgrades, CARB partnered with Columbus Property Management and Development, Inc. on a community-scale gut rehabilitation project located at 56th Street and Walnut Street in Philadelphia, consisting of 32 units in eleven 3-story buildings. These buildings were built in the early 1900s using stone foundations and solid brick-masonry walls. They were renovated in the 1990s to have interior light gauge metal framing with R-13 batt in the above-grade walls, induced-draft furnaces, and central air conditioning.

  5. The Impact of Variant Philadelphia Chromosome Translocations on the Clinical Course of Chronic Myeloid Leukemia

    PubMed Central

    Eyüpoğlu, Damla; Bozkurt, Süreyya; Haznedaroğlu, İbrahim; Büyükaşık, Yahya; Güven, Deniz

    2016-01-01

    Chronic myeloid leukemia (CML) is genetically characterized by the presence of the reciprocal translocation t(9;22) with the formation of Philadelphia (Ph) chromosome. Sometimes, the Ph translocation is generated by variant rearrangements. The prognostic impact of the variant translocations is still controversial. Among the 180 patients with Ph-positive CML who were treated in Hacettepe University Faculty of Medicine Division of Hematology, variant translocations were detected, and retrospectively clinical and prognostic features were described. Also we performed a comprehensive literature review on the prognosis of such variant cases before and after tyrosine kinase inhibitor era. Five patients (2.7%) had variant Ph chromosomes, involved in the rearrangements were chromosomes 2 (2 cases), 11, 14 and 15. Patients were treated with imatinib or dasatinib. All patients reached a stable major molecular response suggesting a prognosis not worse than standard translocation individuals. Our present data were compatible with the data of previous studies indicating no difference in the prognosis between standard and variant translocations in tyrosine kinase inhibitors era of CML. PMID:27020722

  6. Synthetic aperture radar imagery of airports and surrounding areas: Philadelphia Airport

    NASA Technical Reports Server (NTRS)

    Onstott, Robert G.; Gineris, Denise J.

    1990-01-01

    The statistical description of ground clutter at an airport and in the surrounding area is addressed. These data are being utilized in a program to detect microbursts. Synthetic Aperture Radar (SAR) data were collected at the Philadelphia Airport. These data and the results of the clutter study are described. This 13 km x 10 km scene was imaged at 9.38 GHz and HH-polarization and contained airport grounds and facilities (6 percent), industrial (14 percent), residential (14 percent), fields (10 percent), forest (8 percent), and water (33 percent). Incidence angles ranged from 40 to 84 deg. Even at the smallest incidence angles, the distributed targets such as forest, fields, water, and residential rarely had mean scattering coefficients greater than -10 dB. Eighty-seven percent of the image had scattering coefficients less than -17.5 dB. About 1 percent of the scattering coefficients exceeded 0 dB, with about 0.1 percent above 10 dB. Sources which produced the largest cross sections were largely confined to the airport grounds and areas highly industrialized. The largest cross sections were produced by observing broadside large buildings surrounded by smooth surfaces.

  7. Exchange of Nitrogen through an Urban Tidal Freshwater Wetland in Philadelphia, Pennsylvania.

    PubMed

    Elsey-Quirk, Tracy; Smyth, A; Piehler, M; Mead, J V; Velinsky, D J

    2013-01-01

    Tidal freshwater wetlands in urban settings can be subject to elevated N concentrations, which can promote the exchange of N between the marsh, water, and atmosphere, including denitrification. We used a multitiered approach consisting of direct measurements of N fluxes and denitrification, tidal hypsometry, and N load modeling to examine N exchanges in an urban tidal freshwater wetland of the Delaware River Estuary, Philadelphia, PA. Sediment cores and aboveground biomass were collected at 20 locations across a range of elevations and plant communities in April, July, and October 2010. Nitrate was taken up by the marsh during all seasons. In the spring, the high rate of NH production from the sediment was correlated with NO uptake, suggesting dissimilatory reduction to NH as a potentially important process. Denitrification rates were greatest in July, averaging 5.5 ± 0.6 mg N m h. Adjusted for tidal inundation using a refined digital elevation model, denitrification averaged 0.08, 0.5, and 0.2 g N m mo for April, July, and October, respectively. Less than 10% of the modeled N load was estimated to have been removed in the months measured. A combination of high N load, limited marsh area that represented ∼1% of the watershed area, and conservative extrapolation of denitrification rates contributed to the low estimate of the N load attenuated. PMID:23673851

  8. ABL kinase mutation and relapse in 4 pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia cases.

    PubMed

    Aoe, Michinori; Shimada, Akira; Muraoka, Michiko; Washio, Kana; Nakamura, Yoshimi; Takahashi, Takahide; Imada, Masahide; Watanabe, Toshiyuki; Okada, Ken; Nishiuchi, Ritsuo; Miyamura, Takako; Chayama, Kosuke; Shibakura, Misako; Oda, Megumi; Morishima, Tsuneo

    2014-01-01

    The tyrosine kinase inhibitor (TKI) imatinib mesylate (IM) revolutionized the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-ALL), which had showed poor prognosis before the dawn of IM treatment. However, if Ph-ALL patients showed IM resistance due to ABL kinase mutation, second-generation TKI, dasatinib or nilotinib, was recommended. We treated 4 pediatric Ph-ALL patients with both IM and bone marrow transplantation (BMT); however, 3 relapsed. We retrospectively examined the existence of ABL kinase mutation using PCR and direct sequencing methods, but there was no such mutation in all 4 diagnostic samples. Interestingly, two relapsed samples from patients who were not treated with IM before relapse did not show ABL kinase mutation and IM was still effective even after relapse. On the other hand, one patient who showed resistance to 3 TKI acquired dual ABL kinase mutations, F359C at the IM-resistant phase and F317I at the dasatinib-resistant phase, simultaneously. In summary, Ph-ALL patients relapsed with or without ABL kinase mutation. Furthermore, ABL kinase mutation was only found after IM treatment, so an IM-resistant clone might have been selected during the IM treatment and intensive chemotherapy. The appropriate combination of TKI and BMT must be discussed to cure Ph-ALL patients. PMID:24652384

  9. Targeting BCL-2 and ABL/LYN in Philadelphia chromosome-positive acute lymphoblastic leukemia.

    PubMed

    Leonard, Jessica T; Rowley, Joelle S J; Eide, Christopher A; Traer, Elie; Hayes-Lattin, Brandon; Loriaux, Marc; Spurgeon, Stephen E; Druker, Brian J; Tyner, Jeffrey W; Chang, Bill H

    2016-08-31

    Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+)ALL) remains a challenge. Although the addition of targeted tyrosine kinase inhibitors (TKIs) to standard cytotoxic therapy has greatly improved upfront treatment, treatment-related morbidity and mortality remain high. TKI monotherapy provides only temporary responses and renders patients susceptible to the development of TKI resistance. Thus, identifying agents that could enhance the activity of TKIs is urgently needed. Recently, a selective inhibitor of B cell lymphoma 2 (BCL-2), ABT-199 (venetoclax), has shown impressive activity against hematologic malignancies. We demonstrate that the combination of TKIs with venetoclax is highly synergistic in vitro, decreasing cell viability and inducing apoptosis in Ph(+)ALL. Furthermore, the multikinase inhibitors dasatinib and ponatinib appear to have the added advantage of inducing Lck/Yes novel tyrosine kinase (LYN)-mediated proapoptotic BCL-2-like protein 11 (BIM) expression and inhibiting up-regulation of antiapoptotic myeloid cell leukemia 1 (MCL-1), thereby potentially overcoming the development of venetoclax resistance. Evaluation of the dasatinib-venetoclax combination for the treatment of primary Ph(+)ALL patient samples in xenografted immunodeficient mice confirmed the tolerability of this drug combination and demonstrated its superior antileukemic efficacy compared to either agent alone. These data suggest that the combination of dasatinib and venetoclax has the potential to improve the treatment of Ph(+)ALL and should be further evaluated for patient care. PMID:27582059

  10. Water quality data for precipitation and storm runoff in Pennypack Creek Basin, Philadelphia, Pennsylvania

    USGS Publications Warehouse

    Speight, D.W.

    1989-01-01

    This report presents data on the chemistry of precipitation and storm runoff that were collected during 29 storms from July 1979 through November 1980, in an urban environment in the Pennypack Creek basin, Philadelphia, Pennsylvania. Daily mean and instantaneous stream discharge data were collected at two U.S. Geological Survey gaging stations. Water-quality data collected from these sites and from one storm-sewer sampling site included nutrients, chemical and biochemical oxygen demands, solids, metals, major anions, other constituents, and pH. Instantaneous loads of selected constituents were computed. Chemical oxygen demand, biochemical oxygen demand, sulfate, alkalinity, chloride, and dissolved solids generally were low in precipitation and runoff. During the November 5, 1980 storm at Pine Road, dissolved nitrate concentrations equaled or exceeded 10 milligrams per liter in 17 percent of the samples analyzed and dissolved ammonia nitrogen concentrations exceeded 2.5 milligrams per liter. Generally, a comparison of median concentration of copper, lead, or zinc in precipitation and runoff at the Tustin Street storm-sewer site showed that median concentrations in precipitation were greater than those in runoff.

  11. African American community leaders' policy recommendations for reducing racial disparities in HIV infection, treatment, and care: results from a community-based participatory research project in Philadelphia, Pennsylvania.

    PubMed

    Nunn, Amy; Sanders, Julia; Carson, Lee; Thomas, Gladys; Cornwall, Alexandra; Towey, Caitlin; Lee, Hwajin; Tasco, Marian; Shabazz-El, Waheedah; Yolken, Annajane; Smith, Tyrone; Bell, Gary; Feller, Sophie; Smith, Erin; James, George; Shelton Dunston, Brenda; Green, Derek

    2015-01-01

    African Americans account for 45% of new HIV infections in the United States. Little empirical research investigates African American community leaders' normative recommendations for addressing these disparities. Philadelphia's HIV infection rate is 5 times the national average, nearly 70% of new infections are among African Americans, and 2% of African Americans in Philadelphia are living with HIV/AIDS. Using a community-based participatory research approach, we convened focus groups among 52 African American community leaders from diverse backgrounds to solicit normative recommendations for reducing Philadelphia's racial disparities in HIV infection. Leaders recommended that (a) Philadelphia's city government should raise awareness about HIV/AIDS with media campaigns featuring local leaders, (b) local HIV-prevention interventions should address social and structural factors influencing HIV risks rather than focus exclusively on mode of HIV transmission, (c) resources should be distributed to the most heavily affected neighborhoods of Philadelphia, and (d) faith institutions should play a critical role in HIV testing, treatment, and prevention efforts. We developed a policy memo highlighting these normative recommendations for how to enhance local HIV prevention policy. This policy memo led to Philadelphia City Council hearings about HIV/AIDS in October 2010 and subsequently informed local HIV/AIDS prevention policy and development of local HIV prevention interventions. This community-based participatory research case study offers important lessons for effectively engaging community leaders in research to promote HIV/AIDS policy change. PMID:24879446

  12. African American community leaders' policy recommendations for reducing racial disparities in HIV infection, treatment and care: results from a community-based participatory research project in Philadelphia, PA

    PubMed Central

    Nunn, Amy; Sanders, Julia; Carson, Lee; Thomas, Gladys; Cornwall, Alexandra; Towey, Caitlin; Lee, Hwajin; Tasco, Marian; Shabazz-El, Waheedah; Yolken, Annajane; Smith, Tyrone; Bell, Gary; Feller, Sophie; Smith, Erin; James, George; Dunston, Brenda Shelton; Green, Derek

    2015-01-01

    African Americans account for 45% of new HIV infections in the United States. Little empirical research investigates African American community leaders' normative recommendations for addressing these disparities. Philadelphia's HIV infection rate is five times the national average, nearly 70% of new infections are among African Americans, and 2% of African Americans in Philadelphia are living with HIV/AIDS. Using a community-based participatory research (CBPR) approach, we convened focus groups among 52 African American community leaders from diverse backgrounds to solicit normative recommendations for reducing Philadelphia's racial disparities in HIV infection. Leaders recommended: 1) Philadelphia's city government should raise awareness about HIV/AIDS with media campaigns featuring local leaders; 2) Local HIV prevention interventions should address social and structural factors influencing HIV risks rather than focus exclusively on mode of HIV transmission; 3) Resources should be distributed to the most heavily impacted neighborhoods of Philadelphia; and 4) Faith institutions should play a critical role in HIV testing, treatment and prevention efforts. We developed a policy memo highlighting these normative recommendations for how to enhance local HIV prevention policy. This policy memo led to Philadelphia City Council hearings about HIV/AIDS in October 2010 and subsequently informed local HIV/AIDS prevention policy and development of local HIV prevention interventions. This CBPR case study offers important lessons for effectively engaging community leaders in research to promote HIV/AIDS policy change. PMID:24879446

  13. Having a patient advocate dedicated to the ED.

    PubMed

    2008-02-01

    The ED at St. Mary's Hospital in Tucson, AZ, has its own departmental patient advocate. This new staff position saves a lot of time for the rest of the team members. Here are some of the functions a patient advocate can perform in your ED: proactively prevent problems and satisfy delivery of care needs in a timelier manner to avoid complaints; train the ED staff in customer service and communication techniques; communicate with outside clinics to support uninsured or underinsured patients who don't have primary care physicians. PMID:18447293

  14. Philadelphia Geriatric Morale Scale in Essential Tremor: A Population-Based Study in Three Spanish Communities

    PubMed Central

    Louis, Elan D.; Benito-León, Julián; Bermejo-Pareja, Félix

    2009-01-01

    BACKGROUND Essential tremor (ET) is associated with both functional disability and depression. Each could contribute to a poor sense of well-being and low morale. We hypothesized that morale would be lower in ET cases than controls. METHODS Using a population-based, cross-sectional design, morale was assessed in 187 ET cases and 561 matched controls living in three communities in central Spain using the Philadelphia Geriatric Center Morale Scale (PGCMS)(range = 0 [low morale]–17), which included three dimensions of psychological well-being: agitation, lonely dissatisfaction, and attitude toward own aging. RESULTS The PGCMS score was lower in ET cases than controls (9.41 ± 3.21 vs. 10.39 ± 2.92, p < 0.001), as were the Agitation subscore (3.17 ± 1.71 vs. 3.78 ± 1.67, p < 0.001) and Lonely Dissatisfaction subscore (3.75 ± 1.34 vs. 4.02 ± 1.24, p < 0.05). Nearly one-half of the ET cases were classified as having low morale compared with only one-third of controls (p = 0.006). In a linear regression analysis adjusting for demographic factors and multiple comorbid conditions, ET cases had a lower log PGCMS score than controls (p < 0.001). Exclusion of participants on antidepressant medication did not change the results. CONCLUSIONS Our results indicate that morale is significantly lower in community-dwelling ET cases than in matched controls. This lower morale could in part be a proxy for mild, untreated depression. It therefore seems important to detect and then possibly treat this problem to improve the psychological well-being of patients with this disease. PMID:18512746

  15. Cost and effectiveness of an eye care adherence program for Philadelphia children with significant visual impairment.

    PubMed

    Pizzi, Laura T; Snitzer, Melanie; Amos, Tony; Prioli, Katherine M; Steele, Deon; Levin, Alex V

    2015-06-01

    The follow-up rate among children with vision problems in the authors' outreach programs has been <5%. The authors therefore developed a social worker (SW) intervention, the Children's Eye Care Adherence Program (CECAP), for Philadelphia school children. The objective of this study was to measure CECAP's effectiveness and cost, as well as to identify barriers to care through a conceptual framework and geomapping software. A SW reviewed records to identify children needing follow-up and phoned families to identify and resolve barriers to eye care and scheduled appointments. Effectiveness was defined as the percent completing ≥ 1 follow-up visit within the physician-recommended time frame. Cost was measured for SW time (SW wage rates+benefits) and additional materials (forms, postage, phone charges). Barriers were organized into a conceptual framework depicting predisposing factors, system factors, and financial factors. Geomapping software was used to illustrate follow-up rates. In all, 120 patients required additional pediatric ophthalmic care; 71 patients were contacted and returned for care (59.2%); 49 patients were contacted but did not return (40.8%). SW time was 3h rs/patient for those who returned and 2 hrs/patient for those who did not return. Based on the CECAP program total cost ($14,249) and the reimbursement payment ($6265.66), the net cost of the CECAP program was $7983.59. Predisposing factors were the primary barrier theme for patients who did not follow up. CECAP significantly improved adherence to eye care but comes at an additional cost. Future efforts should focus on reducing operational efficiencies and targeting CECAP based on predictors of follow-up. PMID:25647611

  16. Photokeratitis Linked to Metal Halide Bulbs in Two Gymnasiums - Philadelphia, Pennsylvania, 2011 and 2013.

    PubMed

    Finn, Lauren E; Gutowski, Jennifer; Alles, Steve; Mirowitz, Naomi; Johnson, Caroline; Osterhoudt, Kevin C; Patel, Ami

    2016-01-01

    In December 2011 and December 2013, the Philadelphia Department of Public Health (PDPH) received separate reports of clusters of photokeratitis linked to gymnasium events. Photokeratitis, a painful eye condition resulting from unprotected exposure to ultraviolet radiation, has previously been linked to metal halide lamps with broken outer envelopes (1,2). To investigate the cause of these clusters and further characterize patients with photokeratitis, PDPH administered questionnaires to potentially exposed persons, established a case definition, and conducted environmental assessments of both gymnasiums. Because event attendee registration information was available, a cohort study was conducted to evaluate the 2011 cluster of 242 persons who met the photokeratitis case definition. A case-series investigation was conducted to evaluate the 2013 cluster of 20 persons who met the photokeratitis case definition for that event. These investigations indicated that Type R metal halide bulbs with broken outer envelopes found in both gymnasiums were the probable cause of the photokeratitis. The Food and Drug Administration has made a number of recommendations regarding the use of metal halide bulbs in facilities where bulbs are at elevated risk for breaking, such as schools and indoor sports facilities (3). Because Type R metal halide lamps do not self-extinguish once the outer envelope is broken, these bulbs should be removed from settings with a high risk for outer envelope rupture, such as gymnasiums, or should be placed within enclosed fixtures. In instances where these bulbs cannot be exchanged for self-extinguishing lamps, Type R lamps with a broken outer envelope should be replaced immediately to limit exposure to ultraviolet radiation. A broken outer envelope can be detected by the presence of glass on the floor, or visual examination of the bulb when the power is turned off. A broken outer envelope is difficult to detect when the lamp is emitting light. PMID

  17. Dasatinib and low-intensity chemotherapy in elderly patients with Philadelphia chromosome-positive ALL.

    PubMed

    Rousselot, Philippe; Coudé, Marie Magdelaine; Gokbuget, Nicola; Gambacorti Passerini, Carlo; Hayette, Sandrine; Cayuela, Jean-Michel; Huguet, Françoise; Leguay, Thibaut; Chevallier, Patrice; Salanoubat, Celia; Bonmati, Caroline; Alexis, Magda; Hunault, Mathilde; Glaisner, Sylvie; Agape, Philippe; Berthou, Christian; Jourdan, Eric; Fernandes, José; Sutton, Laurent; Banos, Anne; Reman, Oumedaly; Lioure, Bruno; Thomas, Xavier; Ifrah, Norbert; Lafage-Pochitaloff, Marina; Bornand, Anne; Morisset, Laure; Robin, Valérie; Pfeifer, Heike; Delannoy, Andre; Ribera, Josep; Bassan, Renato; Delord, Marc; Hoelzer, Dieter; Dombret, Herve; Ottmann, Oliver G

    2016-08-11

    Prognosis of Philadelphia-positive (Ph(+)) acute lymphoblastic leukemia (ALL) in the elderly has improved during the imatinib era. We investigated dasatinib, another potent tyrosine kinase inhibitor, in combination with low-intensity chemotherapy. Patients older than age 55 years were included in the European Working Group on Adult ALL (EWALL) study number 01 for Ph(+) ALL (EWALL-PH-01 international study) and were treated with dasatinib 140 mg/day (100 mg/day over 70 years) with intrathecal chemotherapy, vincristine, and dexamethasone during induction. Patients in complete remission continued consolidation with dasatinib, sequentially with cytarabine, asparaginase, and methotrexate for 6 months. Maintenance therapy was dasatinib and vincristine/dexamethasone reinductions for 18 months followed by dasatinib until relapse or death. Seventy-one patients with a median age of 69 years were enrolled; 77% had a high comorbidity score. Complete remission rate was 96% and 65% of patients achieved a 3-log reduction in BCR-ABL1 transcript levels during consolidation. Only 7 patients underwent allogeneic hematopoietic stem cell transplantation. At 5 years, overall survival was 36% and up to 45% taking into account deaths unrelated to disease or treatment as competitors. Thirty-six patients relapsed, 24 were tested for mutation by Sanger sequencing, and 75% were T315I-positive. BCR-ABL1(T315I) was tested by allele-specific oligonucleotide reverse transcription-quantitative polymerase chain reaction in 43 patients and detection was associated with short-term relapses. Ten patients (23%) were positive before any therapy and 8 relapsed, all with this mutation. In conclusion, dasatinib combined with low-intensity chemotherapy was well-tolerated and gave long-term survival in 36% of elderly patients with Ph(+) ALL. Monitoring of BCR-ABL1(T315I) from diagnosis identified patients with at high risk of early relapse and may help to personalize therapy. PMID:27121472

  18. Philadelphia chromosome-positive leukemia stem cells in acute lymphoblastic leukemia and tyrosine kinase inhibitor therapy

    PubMed Central

    Thomas, Xavier

    2012-01-01

    Leukemia stem cells (LSCs), which constitute a minority of the tumor bulk, are functionally defined on the basis of their ability to transfer leukemia into an immunodeficient recipient animal. The presence of LSCs has been demonstrated in acute lymphoblastic leukemia (ALL), of which ALL with Philadelphia chromosome-positive (Ph+). The use of imatinib, a tyrosine kinase inhibitor (TKI), as part of front-line treatment and in combination with cytotoxic agents, has greatly improved the proportions of complete response and molecular remission and the overall outcome in adults with newly diagnosed Ph+ ALL. New challenges have emerged with respect to induction of resistance to imatinib via Abelson tyrosine kinase mutations. An important recent addition to the arsenal against Ph+ leukemias in general was the development of novel TKIs, such as nilotinib and dasatinib. However, in vitro experiments have suggested that TKIs have an antiproliferative but not an antiapoptotic or cytotoxic effect on the most primitive ALL stem cells. None of the TKIs in clinical use target the LSC. Second generation TKI dasatinib has been shown to have a more profound effect on the stem cell compartment but the drug was still unable to kill the most primitive LSCs. Allogeneic stem cell transplantation (SCT) remains the only curative treatment available for these patients. Several mechanisms were proposed to explain the resistance of LSCs to TKIs in addition to mutations. Hence, TKIs may be used as a bridge to SCT rather than monotherapy or combination with standard chemotherapy. Better understanding the biology of Ph+ ALL will open new avenues for effective management. In this review, we highlight recent findings relating to the question of LSCs in Ph+ ALL. PMID:22993661

  19. Concurrent sexual partnerships among African American women in Philadelphia: results from a qualitative study

    PubMed Central

    Nunn, Amy; Dickman, Samuel; Cornwall, Alexandra; Kwakwa, Helena; Mayer, Kenneth H.; Rosengard, Cynthia

    2014-01-01

    Background African American women are disproportionately affected by HIV/AIDS. Concurrent sexual partnerships may contribute to racial disparities in HIV infection. Little is known about attitudes and practices related to concurrency among African American women and the social, structural and behavioral factors that influence concurrency. Methods We recruited 19 heterosexual African American women engaging in concurrent sexual partnerships from a public health clinic in Philadelphia in 2009. We conducted in-depth interviews exploring social norms, attitudes and practices about concurrency, and the structural, social and behavioral factors influencing concurrent sexual partnerships. Grounded theory guided interview protocols and data analysis. Results Seventeen women reported one main and one or more non-main partners; two reported no main partners. Many women used condoms more frequently with non-main than main partners, noting they trust main partners more than non-main partners. Social factors influencing concurrency included social normalization of concurrency, inability to negotiate partners’ other concurrent partnerships, being unmarried, and not trusting main and non-main partners. Not trusting partners and the community at large were the most commonly cited reasons that women engaged in concurrent partnerships. Structural factors included economic dependence on partners, partners’ dependence on women for economic support and housing, and incarceration that interrupted partnerships. Behavioral factors including alcohol and cocaine use influenced concurrency. Conclusions Social, structural, and behavioral factors strongly influenced these African American women’s concurrent sexual partnerships. Many evidence-based interventions (EBIs) disseminated by the US Centers for Disease Control and Prevention (CDC) focus largely on behavioral factors and may fail to address the social and structural factors influencing African American women’s sexual networks

  20. Motivations for prescription drug misuse among young men who have sex with men (YMSM) in Philadelphia

    PubMed Central

    Kecojevic, Aleksandar; Corliss, Heather L.; Lankenau, Stephen E.

    2015-01-01

    Background Prescription drug misuse (i.e. opioids, tranquilizers and stimulants) has become the fastest growing area of substance abuse among young adults. Limited studies focus on prescription drug misuse among young men who have sex with men (YMSM, aged 18–29 years). Furthermore, little is known about YMSM’s motivations for misuse. The purpose of this study was to explore personal motivations for prescription drug misuse among YMSM, including the possible connection between misuse and sexual behaviors. Methods As part of a larger mixed methods study of 191 YMSM recruited in Philadelphia during 2012–2013, we conducted semi-structured qualitative interviews with 25 of these participants to gather additional contextual information about their prescription drug misuse. We conducted thematic analysis of qualitative data. Results While our results corroborated previous literature on motives for misuse of prescription drugs, our data yielded some distinct motivations specific among YMSM. These motives included social/recreational motives, facilitating sex with other men (including motives such as use of opioids for less painful anal receptive sex), and psychological motives such as depression, stress management, coping with everyday hardships (opioids and tranquilizers) or feeling more energized (stimulants). Prescription drugs were commonly misused within the broader contexts of participants' polysubstance use, adding to the significance of this problem. Conclusions Our findings offer insights into YMSM’s motivations for prescription drug misuse, and point to the importance of recognizing and addressing them. While substance use is likely related to various psychosocial issues impacting YMSM, it also may lead to significant health consequences. Results support the need to include prescription drugs and polysubstance use in harm reduction messages and treatment approaches aimed at substance using YMSM. PMID:25936445

  1. Current Concepts in Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

    PubMed Central

    Bernt, Kathrin M.; Hunger, Stephen P.

    2014-01-01

    The t(9;22)(q34;q11) or Philadelphia chromosome creates a BCR–ABL1 fusion gene encoding for a chimeric BCR–ABL1 protein. It is present in 3–4% of pediatric acute lymphoblastic leukemia (Ph+ ALL), and about 25% of adult ALL cases. Prior to the advent of tyrosine kinase inhibitors (TKI), Ph+ ALL was associated with a very poor prognosis despite the use of intensive chemotherapy and frequently hematopoietic stem-cell transplantation (HSCT) in first remission. The development of TKIs revolutionized the therapy of Ph+ ALL. Addition of the first generation ABL1 class TKI imatinib to intensive chemotherapy dramatically increased the survival for children with Ph+ ALL and established that many patients can be cured without HSCT. In parallel, the mechanistic understanding of Ph+ ALL expanded exponentially through careful mapping of pathways downstream of BCR–ABL1, the discovery of mutations in master regulators of B-cell development such as IKZF1 (Ikaros), PAX5, and early B-cell factor (EBF), the recognition of the complex clonal architecture of Ph+ ALL, and the delineation of genomic, epigenetic, and signaling abnormalities contributing to relapse and resistance. Still, many important basic and clinical questions remain unanswered. Current clinical trials are testing second generation TKIs in patients with newly diagnosed Ph+ ALL. Neither the optimal duration of therapy nor the optimal chemotherapy backbone are currently defined. The role of HSCT in first remission and post-transplant TKI therapy also require further study. In addition, it will be crucial to continue to dig deeper into understanding Ph+ ALL at a mechanistic level, and translate findings into complementary targeted approaches. Expanding targeted therapies hold great promise to decrease toxicity and improve survival in this high-risk disease, which provides a paradigm for how targeted therapies can be incorporated into treatment of other high-risk leukemias. PMID:24724051

  2. Black carbon concentrations in a goods-movement neighborhood of Philadelphia, PA

    PubMed Central

    Mizes, Chris; Lee, John; Burstyn, Igor

    2014-01-01

    Communities along the Delaware River in Philadelphia, USA such as Port Richmond, are subject to traffic associated with goods movement to and from port facilities and local industry. Air pollution associated with this traffic poses an environmental health concern in this and other urban areas. Our study measures black carbon (BC) in Port Richmond and examines its relationship to expected sources such as truck traffic. We used a participatory sampling method to conduct 1-min measurements over 8-hour periods at 14 homes, a school and park, during a 4-week period in June 2012. Measurements over 9 sampling days had a 30-min average BC concentration of 1.2 μg m−3, and a maximum of 12 μg m−3. Statistical analyses showed some effect of traffic, but greater association between BC concentrations and weather and time of day. BC concentrations varied more by location than by day, and distance to traffic arterials and interstate freeway was a predictor of this variance. While our dataset is limited by number and variety of observations, major findings indicate that BC concentration varies more by location than by day, there is a decrease in median BC concentration with increased distance from an interstate highway, and an expected effect of diesel traffic on average daily BC concentrations. Our findings are an important step towards understanding patterns and determinants of BC concentration in communities colocated with major ports. Our study also demonstrates that participatory methods in air pollution monitoring can help increase awareness of local air pollution levels. PMID:24668123

  3. Concentration of Tobacco Advertisements at SNAP and WIC Stores, Philadelphia, Pennsylvania, 2012

    PubMed Central

    Chilton, Mariana; Zhao, Qian-Wei; Szymkowiak, Dorota; Coffman, Ryan; Mallya, Giridhar

    2015-01-01

    Introduction Tobacco advertising is widespread in urban areas with racial/ethnic minority and low-income households that participate in nutrition assistance programs. Tobacco sales and advertising are linked to smoking behavior, which may complicate matters for low-income families struggling with disparate health risks relating to nutrition and chronic disease. We investigated the relationship between the amount and type of tobacco advertisements on tobacco outlets and the outlet type and location. Methods By using field visits and online images, we inspected all licensed tobacco retail outlets in Philadelphia (N = 4,639). Point pattern analyses were used to identify significant clustering of tobacco outlets and outlets with exterior tobacco advertisements. Logistic regression was used to analyze the relationship between the outlet’s acceptance of Supplemental Nutrition Assistance Program (SNAP) and Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and the presence of tobacco advertisements. Results Tobacco outlets with exterior tobacco advertisements were significantly clustered in several high-poverty areas. Controlling for racial/ethnic and income composition and land use, SNAP and WIC vendors were significantly more likely to have exterior (SNAP odds ratio [OR], 2.11; WIC OR, 1.59) and interior (SNAP OR, 3.43; WIC OR, 1.69) tobacco advertisements than other types of tobacco outlets. Conclusion Tobacco advertising is widespread at retail outlets, particularly in low-income and racial/ethnic minority neighborhoods. Policy makers may be able to mitigate the effects of this disparate exposure through tobacco retail licensing, local sign control rules, and SNAP and WIC authorization. PMID:25654220

  4. Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms.

    PubMed

    Skov, Vibe; Larsen, Thomas Stauffer; Thomassen, Mads; Riley, Caroline Hasselbalch; Jensen, Morten K; Bjerrum, Ole Weis; Kruse, Torben A; Hasselbalch, Hans Carl

    2012-01-01

    Myeloproliferation, myeloaccumulation (decreased apoptosis), inflammation, bone marrow fibrosis and angiogenesis are cardinal features of the Philadelphia-negative chronic myeloproliferative neoplasms: essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF). Histone deacetylases (HDACs) have a critical role in modulating gene expression and, accordingly, in the control of cell pathobiology and cancer development. HDAC inhibition has been shown to inhibit tumor growth (impaired myeloproliferation), to modulate the balance between pro- and antiapoptotic proteins in favor of apoptosis (enhanced apoptosis) and also to inhibit angiogenesis. Recently, enhanced HDAC enzyme activity has been found in CD34+cells from patients with PMF, enzyme activity levels highly exceeding those recorded in other chronic myeloproliferative neoplasms (CMPNs). The raised levels correlated to the degree of splenomegaly, suggesting that HDAC might be recruited as ET or PV progresses into myelofibrosis or PMF progresses into a more advanced stage. Accordingly, HDAC inhibition is an obvious novel therapeutic approach in these neoplasms. Using global gene expression profiling of whole blood from patients with CMPNs, we have found a pronounced deregulation of HDAC genes, involving significant up-regulation of the HDAC genes 9 and 11, with the highest expression levels being found in patients with ET (HDAC9 and 11), PMF (HDAC9) and CMPNs (both HDAC9 and HDAC11). Furthermore, we have identified that the HDAC6 gene is progressively expressed in patients with ET, PV and PMF, reflecting a steady accumulation of abnormally expressed HDAC6 during disease evolution. Our results lend further support to HDACs as important epigenetic targets in the future treatment of patients with CMPNs. Since the highest expression levels of HDAC genes were recorded in ET, in PMF and in the entire CMPN group, their down-regulation by HDAC inhibitors might be associated with decreased disease

  5. Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia.

    PubMed

    Kim, Dae-Young; Joo, Young-Don; Lim, Sung-Nam; Kim, Sung-Doo; Lee, Jung-Hee; Lee, Je-Hwan; Kim, Dong Hwan Dennis; Kim, Kihyun; Jung, Chul Won; Kim, Inho; Yoon, Sung-Soo; Park, Seonyang; Ahn, Jae-Sook; Yang, Deok-Hwan; Lee, Je-Jung; Lee, Ho-Sup; Kim, Yang Soo; Mun, Yeung-Chul; Kim, Hawk; Park, Jae Hoo; Moon, Joon Ho; Sohn, Sang Kyun; Lee, Sang Min; Lee, Won Sik; Kim, Kyoung Ha; Won, Jong-Ho; Hyun, Myung Soo; Park, Jinny; Lee, Jae Hoon; Shin, Ho-Jin; Chung, Joo-Seop; Lee, Hyewon; Eom, Hyeon-Seok; Lee, Gyeong Won; Cho, Young-Uk; Jang, Seongsoo; Park, Chan-Jeoung; Chi, Hyun-Sook; Lee, Kyoo-Hyung

    2015-08-01

    We investigated the effects of nilotinib plus multiagent chemotherapy, followed by consolidation/maintenance or allogeneic hematopoietic cell transplantation (allo-HCT) for adult patients with newly diagnosed Philadelphia-positive (Ph-pos) acute lymphoblastic leukemia (ALL). Study subjects received induction treatment that comprised concurrent vincristine, daunorubicin, prednisolone, and nilotinib. After achieving complete hematologic remission (HCR), subjects received either 5 courses of consolidation, followed by 2-year maintenance with nilotinib, or allo-HCT. Minimal residual disease (MRD) was assessed at HCR, and every 3 months thereafter. The molecular responses (MRs) were defined as MR3 for BCR-ABL1/G6PDH ratios ≤10(-3) and MR5 for ratios <10(-5). Ninety evaluable subjects, ages 17 to 71 years, were enrolled in 17 centers. The HCR rate was 91%; 57 subjects received allo-HCT. The cumulative MR5 rate was 94%; the 2-year hematologic relapse-free survival (HRFS) rate was 72% for 82 subjects that achieved HCR, and the 2-year overall survival rate was 72%. Subjects that failed to achieve MR3 or MR5 were 9.1 times (P = .004) or 6.3 times (P = .001) more prone to hematologic relapse, respectively, than those that achieved MR3 or MR5. MRD statuses just before allo-HCT and at 3 months after allo-HCT were predictive of 2-year HRFS. Adverse events occurred mainly during induction, and most were reversible with dose reduction or transient interruption of nilotinib. The combination of nilotinib with high-dose cytotoxic drugs was feasible, and it effectively achieved high cumulative complete molecular remission and HRFS rates. The MRD status at early postremission time was predictive of the HRFS. This trial was registered at www.clinicaltrials.gov as #NCT00844298. PMID:26065651

  6. Philadelphia-Negative Classical Myeloproliferative Neoplasms: Critical Concepts and Management Recommendations From European LeukemiaNet

    PubMed Central

    Barbui, Tiziano; Barosi, Giovanni; Birgegard, Gunnar; Cervantes, Francisco; Finazzi, Guido; Griesshammer, Martin; Harrison, Claire; Hasselbalch, Hans Carl; Hehlmann, Rudiger; Hoffman, Ronald; Kiladjian, Jean-Jacques; Kröger, Nicolaus; Mesa, Ruben; McMullin, Mary F.; Pardanani, Animesh; Passamonti, Francesco; Vannucchi, Alessandro M.; Reiter, Andreas; Silver, Richard T.; Verstovsek, Srdan; Tefferi, Ayalew

    2011-01-01

    We present a review of critical concepts and produce recommendations on the management of Philadelphia-negative classical myeloproliferative neoplasms, including monitoring, response definition, first- and second-line therapy, and therapy for special issues. Key questions were selected according the criterion of clinical relevance. Statements were produced using a Delphi process, and two consensus conferences involving a panel of 21 experts appointed by the European LeukemiaNet (ELN) were convened. Patients with polycythemia vera (PV) and essential thrombocythemia (ET) should be defined as high risk if age is greater than 60 years or there is a history of previous thrombosis. Risk stratification in primary myelofibrosis (PMF) should start with the International Prognostic Scoring System (IPSS) for newly diagnosed patients and dynamic IPSS for patients being seen during their disease course, with the addition of cytogenetics evaluation and transfusion status. High-risk patients with PV should be managed with phlebotomy, low-dose aspirin, and cytoreduction, with either hydroxyurea or interferon at any age. High-risk patients with ET should be managed with cytoreduction, using hydroxyurea at any age. Monitoring response in PV and ET should use the ELN clinicohematologic criteria. Corticosteroids, androgens, erythropoiesis-stimulating agents, and immunomodulators are recommended to treat anemia of PMF, whereas hydroxyurea is the first-line treatment of PMF-associated splenomegaly. Indications for splenectomy include symptomatic portal hypertension, drug-refractory painful splenomegaly, and frequent RBC transfusions. The risk of allogeneic stem-cell transplantation–related complications is justified in transplantation-eligible patients whose median survival time is expected to be less than 5 years. PMID:21205761

  7. Social, structural and behavioral drivers of concurrent partnerships among African American men in Philadelphia.

    PubMed

    Nunn, Amy; Dickman, Samuel; Cornwall, Alexandra; Rosengard, Cynthia; Kwakwa, Helena; Kim, Daniel; James, George; Mayer, Kenneth H

    2011-11-01

    African Americans face disproportionately higher risks of HIV infection. Concurrent sexual relationships, or sexual partnerships that overlap in time, are more common among African Americans than individuals of other races and may contribute to racial disparities in HIV infection. However, little is known about attitudes, norms and practices among individuals engaged in concurrent partnerships. Little is also known about the processes through which structural, behavioral, and social factors influence concurrent sexual relationships. We recruited 24 heterosexual African American men involved in concurrent sexual relationships from a public health clinic in Philadelphia. We conducted in-depth interviews exploring these men's sexual practices; social norms and individual attitudes about concurrency; perceived sexual health risks with main and non-main partners; and the social, structural, and behavioral factors contributing to concurrent sexual relationships. Twenty-two men reported having one main and one or more non-main partners; two reported having no main partners. Respondents generally perceived sexual relationships with non-main partners as riskier than relationships with main partners and used condoms far less frequently with main than non-main partners. Most participants commented that it is acceptable and often expected for men and women to engage in concurrent sexual relationships. Social factors influencing participants' concurrent partnerships included being unmarried and trusting neither main nor non-main partners. Structural factors influencing concurrent partnerships included economic dependence on one or more women, incarceration, unstable housing, and unemployment. Several men commented that individual behavioral factors such as alcohol and cocaine use contributed to their concurrent sexual partnerships. Future research and interventions related to sexual concurrency should address social and structural factors in addition to conventional HIV risk

  8. Structure of catalase determined by MicroED.

    PubMed

    Nannenga, Brent L; Shi, Dan; Hattne, Johan; Reyes, Francis E; Gonen, Tamir

    2014-01-01

    MicroED is a recently developed method that uses electron diffraction for structure determination from very small three-dimensional crystals of biological material. Previously we used a series of still diffraction patterns to determine the structure of lysozyme at 2.9 Å resolution with MicroED (Shi et al., 2013). Here we present the structure of bovine liver catalase determined from a single crystal at 3.2 Å resolution by MicroED. The data were collected by continuous rotation of the sample under constant exposure and were processed and refined using standard programs for X-ray crystallography. The ability of MicroED to determine the structure of bovine liver catalase, a protein that has long resisted atomic analysis by traditional electron crystallography, demonstrates the potential of this method for structure determination. PMID:25303172

  9. SSF Terra-FM1 Ed3A

    Atmospheric Science Data Center

    2016-07-13

    SSF Terra-FM1 Ed3A Project Title:  CERES Discipline:  Clouds Radiation Budget ...   Reverb Tutorial Subset/Visualization Tool: CERES Order Tool Subset Data:  CERES Search and Subset Tool (HDF4 & ...

  10. SSF Aqua-FM3 Ed3A

    Atmospheric Science Data Center

    2016-07-13

    SSF Aqua-FM3 Ed3A Project Title:  CERES Discipline:  Clouds Radiation Budget ...   Reverb Tutorial Subset/Visualization Tool: CERES Order Tool Subset Data:  CERES Search and Subset Tool (HDF4 & ...

  11. Many Teens Give Sex Ed a Failing Grade

    MedlinePlus

    ... gov/news/fullstory_160906.html Many Teens Give Sex Ed a Failing Grade International study finds courses ... HealthDay News) -- Teens around the world are getting sex education in schools that fail to address their ...

  12. Cancer and lymph nodes

    MedlinePlus

    ... ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2014:chap 69. National Cancer Institute. The Immune System. www.cancer. ... ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2014:chap 69.

  13. Redefining the EdD: Seeking a Separate Identity

    ERIC Educational Resources Information Center

    Boyce, Barbara Ann

    2012-01-01

    The purpose of this manuscript was to discuss the recommendations and guidelines of the Carnegie Group's 2007 effort to "Reclaim the EdD" as well as to outline the work completed at the University of Virginia related to their re-design of the Doctor of Education (EdD) degree. In order to address the re-envision and re-formulation of the Doctor of…

  14. Rethinking the Ed.D., or What's in a Name?

    ERIC Educational Resources Information Center

    Townsend, Barbara K.

    This paper traces the development of the Ed.D., explores the purposes the degree serves, and assesses its value. The creation of the degree stemmed largely from the reluctance of faculty in Arts and Sciences to offer the Ph.D. in professional schools. The one thing most Ed.D. programs have in common is that it is supposed to be an applied or…

  15. Community paramedics fill gaps, take load off EDs.

    PubMed

    2014-03-01

    In a continuing effort to ease demand on busy EDs, some communities are coming up with new ways to leverage paramedics. Under a three-year pilot program in Raleigh, NC, a select group of paramedics with added training are being used to assess patients with mental health or addiction problems and transfer them to alternative facilities when appropriate. In Robbinsdale, MN, a community paramedicine program is filling in care gaps for patients with chronic diseases and other complaints who are at risk for repeat ED visits or inpatient hospitalizations. * Administrators of the Raleigh, NC, program say that in 2013, paramedics diverted more than 300 patients to alternative facilities. Of these, only 20% to 25% need further transport to the hospital. * Every time the NC paramedics divert a patient from the ED to an alternative facility, they return an estimated 14 bed-hours back to the ED. * In addition to responding to patients with non-urgent needs, the Robbinsdale, MN, community paramedicine program is a referral source for ED physicians who are concerned about follow-up care for patients who have presented to the ED with medical problems that require ongoing attention. PMID:24640290

  16. Source identification of atmospheric PCBs in Philadelphia/Camden using positive matrix factorization followed by the potential source contribution function

    NASA Astrophysics Data System (ADS)

    Du, Songyan; Rodenburg, Lisa A.

    The concentrations of gas-phase polychlorinated biphenyls (PCBs) in the atmosphere of the Camden, NJ, USA are elevated by as much as 20 times over regional background. These high PCB levels are a concern because they lead to atmospheric deposition loadings of PCBs to the tidal Delaware River that exceed the entire total maximum daily load (TMDL). Two models were applied to the atmospheric PCB concentration data from Camden in an attempt to identify the PCB source types and regions. Positive matrix factorization (PMF) was used to identify the source types. Four factors were identified which are thought to represent sources such as volatilized Aroclors and particle-phase PCBs. The potential source contribution function (PSCF) model was then used to identify the geographic source regions by examining the origination points for air parcels that result in high PCB concentrations at the Camden receptor site. The PSCF model for ΣPCBs indicates PCB source regions throughout the Philadelphia-Camden metro area, including portions of both Pennsylvania and New Jersey. The PSCF plots for the resolved PMF factors suggest that factors 1-4 show fewer distinct source regions, indicating that their sources are diffuse and/or lie very close to the receptor site. The PSCF plots for factors 2 and 3 reveal very different source regions. Factor 2 primarily arises from the city of Philadelphia, whereas factor 3 originates in southern New Jersey and south of Philadelphia. This study demonstrates the utility of the combined PMF/PSCF approach in identifying atmospheric PCB source types and regions.

  17. Inhibition of MDM2 by Nilotinib Contributes to Cytotoxicity in Both Philadelphia-Positive and Negative Acute Lymphoblastic Leukemia

    PubMed Central

    Liu, Tao; Chiang, Kuang-Yueh; Zhou, Muxiang

    2014-01-01

    Nilotinib is a selective BCR-ABL tyrosine kinase inhibitor related to imatinib that is more potent than imatinib. Nilotinib is widely used to treat chronic myelogenous leukemia (CML) and Philadelphia-positive (Ph+) acute lymphoblastic leukemia (ALL). The present study identifies Mouse double minute 2 homolog (MDM2) as a target of nilotinib. In studying ALL cell lines, we found that the expression of MDM2 in both Philadelphia positive (Ph+) and Philadelphia negative (Ph-) ALL cells was remarkably inhibited by nilotinib, in a dose- and time-dependent manner. Further studies demonstrated that nilotinib inhibited MDM2 at the post-translational level by inducing MDM2 self-ubiquitination and degradation. Nilotinib-mediated MDM2 downregulation did not result in accumulation and activation of p53. Inhibition of MDM2 in nilotinib-treated ALL cells led to downregulation of the anti-apoptotic protein X-linked inhibitor of apoptosis protein (XIAP), a translational target of MDM2, resulting in activation of caspases. Inhibition of XIAP following nilotinib-mediated downregulation of MDM2 resulted in apoptosis of MDM2-expressing ALL; however, similar nilotinib treatment induced stronger apoptosis in Ph+/MDM2+ ALL than in Ph-/MDM2+ or Ph+/MDM2- ALL. The ALL cells that were Ph-/MDM2- were totally resistant to nilotinib. These results suggested that nilotinib can inhibit MDM2 and induce a p53-independent apoptosis pathway by downregulating XIAP; thus, nilotinib can treat not only Ph+, but also Ph- ALL patients whose cancer cells overexpress MDM2. PMID:24968304

  18. Is JAK2V617F Mutation the Only Factor for Thrombosis in Philadelphia-Negative Chronic Myeloproliferative Neoplasms?

    PubMed

    Uyanik, Mehmet Sevki; Baysal, Mehmet; Pamuk, Gulsum Emel; Maden, Muhammet; Akker, Mustafa; Umit, Elif Gulsum; Demir, Muzaffer; Aydogdu, Erkan

    2016-09-01

    The most common genetic disorder in Philadelphia negative chronic myeloproliferative neoplasms is the JAK2-V617F mutation. In the present study, we aimed to determine risk factors for thrombosis in patients with essential thrombocytosis and polycythemia vera. We screened the medical records of 101 patients. Risk factors which may predict thrombosis were recorded. Venous thrombosis (VT) before diagnosis was significantly higher in JAK2 positive patients. VT after diagnosis was similar in JAK2 positive and negative groups, and was significantly higher in elderly patients. Treatment places importance on the JAK2 mutation under unmodifiable cardiovascular risk factors such as advanced age after diagnosis. PMID:27429517

  19. Acute, fatal Sarcocystis calchasi-associated hepatitis in Roller pigeons (Columba livia f. dom.) at Philadelphia Zoo.

    PubMed

    Trupkiewicz, J G; Calero-Bernal, R; Verma, S K; Mowery, J; Davison, S; Habecker, P; Georoff, T A; Ialeggio, D M; Dubey, J P

    2016-01-30

    Four Roller pigeons (Columba livia f. dom.) at the Philadelphia Zoo died suddenly. Necropsy examination revealed macroscopic hepatitis. Microscopically, the predominant lesions were in liver, characterized with necrosis and mixed cell inflammatory response. Sarcocystis calchasi-like schizonts and free merozoites were identified in liver. Transmission electron microscopy confirmed that schizonts were in hepatocytes. A few schizonts were in spleen. PCR using S. calchasi-specific primers confirmed the diagnosis. Neither lesions nor protozoa were found in brain and muscles. This is the first report of acute visceral S. calchasi-associated sarcocystosis in naturally infected avian hosts. PMID:26801595

  20. A report from the American Academy of Neurology 2014 Annual Meeting (April 26-May 3 - Philadelphia, Pennsylvania, USA).

    PubMed

    Rabasseda, X

    2014-06-01

    Not far from the Liberty Bell Hall and the historical parks of old Philadelphia, the Pennsylvania Convention Center hosted this year's American Academy of Neurology Annual Meeting for a full week of integrated science, symposium and general poster sessions. A great amount of research papers were presented and discussed during the meeting by attendees taking refuge from the downpour outside during at least 2 days. But the science was worth staying indoors to witness high-quality research, as summarized in this report. PMID:24983592

  1. Philadelphia's community based drug abuse program: broader medical and social concepts.

    PubMed

    Schut, J

    1975-06-01

    The rehabilitation of drug dependent people has undergone drastic changes since first attempts were made to curb the abuse of illegal drugs. The isolated law-enforcement model proved to be of no use in this area. So, too, the medical model, the psychological model and the public health model proved disappointingly low in their results. During the last ten years, a so-called "metabolic replacement model" has had its upsurge, creating a controversy still under discussion. The Drug Abuse Rehabilitation Programs of the West Philadelphia Community Mental Health Consortium, Inc. have been in the forefront with its treatment models. Established in 1968 as a purely methadone maintenance program, it has evolved into becoming a model, applying community mental health principles. This paper will explore this model further, describing the mechanics of its changes. From a municipal hospital-based methadone dispensing station, the program has developed into a multi-modality project. Three decentralized drug-free outpatient services are located in the midst of the community where the drug abuse problem is more accute. Outreach is emphasized and case-funding is applied. A possibly unique river-front motel was just acquired for the development of a community-based treatment modality. The 94 rooms were converted into a first-floor alcoholism program which also has a "highway safety program" and an intermediate care facility for alcoholics. The second floor of this facility contains outpatient services for the treatment of drug addicts, including a methadone maintenance program, counselling, family therapy and group therapy. The place where most of the emphasis has been placed is the Work Rehabilitation Center (a novel approach whereby patients will spend up to six hours in "partial hospitalization"). Clients will be tested for vocational aptitude and four workshops will be developed on the premises - carpentry, automotive, electricity and clerical. A huge cafeteria with a semi

  2. Authentic Field-Based Learning Experiences for EdD Students

    ERIC Educational Resources Information Center

    Hershberger, Jane Boag

    2009-01-01

    This EPP examines the problem of EdD coursework not having sufficient connection to the work that EdD students will eventually assume as leaders of school districts or other educational systems. It reviews literature critical of EdD programs and websites of educational administration professional organizations with recommended curriculum for EdD…

  3. Foreword: 18th Aps-Sccm and 24th Airapt

    NASA Astrophysics Data System (ADS)

    Collins, Gilbert; Moore, David S.; Yoo, Choong-Shik

    2014-05-01

    This second joint conference between the APS Topical Group on Shock Compression of Condensed Matter and the International Association for the Advancement of High Pressure Science and Technology (AIRAPT) demonstrates that static and dynamic compression of condensed matter continues to be a vibrant field of science and engineering. It is also by its nature an interdisciplinary field, incorporating chemistry, materials science, solid mechanics, plasma physics, and condensed matter physics, and utilizes theoretical, computational, and experimental tools. Recent years have brought about many advances in loading platforms, diagnostics, and computations that are leading to the emergence of many new avenues of research. These advances are also breathing new life into traditional topics such as equations of state, phase transformations, and chemistry at extreme conditions. The plenary lectures by Gennady Kanel, Karl Syassen, David Ceperley, Jon Eggert, Duck Young Kim, and Richard Kraus spanned the disciplines of static and dynamic high pressure physics and illustrated the breadth of the field. They also showed that interesting and important problems remain for researchers of the future to solve. The main guiding principal in the organization of this conference was to intertwine static and dynamical experimental alongside computational and theoretical studies of similar materials. To achieve this goal, we arranged the conference to include static, dynamic, and computational components in the same sessions, quite often taking presenters out of their comfort zone. The three special sessions on Deep Carbon Budget (organized by Giulia Galli and Rus Hemley), High Energy Density Materials (organized by Raymond Jeanloz and Jon Eggert), and Dynamic Response of Materials (organized by Yogendra Gupta and John Sarrao) furthered this guiding principal. We also endeavored to represent the breadth of static and dynamic high pressure science and technology, notably beyond that done at national laboratories. To this end, a significant fraction of the plenary, invited and contributed presentations showcased work done in academia, defense laboratories and industry, as well as internationally. Although travel distance and visa issues always present difficulties, the conference had strong representation from a record number of international participants, including sizable groups from Russia and China (thanks to Tony Zocher and Frank Cherne), as well as Japan, the United Kingdom, France, Canada, Germany, Israel, and Italy. It is our sincere hope that international interactions that occurred at the conference will lead to further collaborations in the future. Finally, we strived to increase student participation at the conference. Through the leadership of Scott Alexander and his committee, a new all-day student symposium was held the day before the main conference, with only student attendees and presenters, in order to acclimate the students to conference participation and help them network with their peers. In cooperation with the APS Topical Group and the AIRAPT and with additional support from DTRA and the AWE, the conference was able to provide financial assistance to a large number of students to attend the conference and present their research. This aid helped increase the number of student attendees significantly over previous conferences. Finally, the conference sponsored a networking lunch for students and representatives from a number of laboratories and other institutions, which was well attended. Seattle proved itself to be an excellent venue for the conference. The international flavor of the city provided ample dining options and numerous activity choices outside of the conference sessions. The major international airport made travel as easy as possible, as Seattle is a convenient central location for attendees from Europe and Asia. The conference was truly a team effort with critical contributions from many individuals. We deeply appreciate their contributions to the success of the conference and the publication of these proceedings. G

  4. The 18th Annual Condensed Matter Physics Meeting

    NASA Astrophysics Data System (ADS)

    Chaplin, Don; Hutchinson, Wayne; Yazidjoglou, Nick; Stewart, Glen

    The Handbook contains abstracts of oral and poster presentations covering various aspects of condensed matter physics such as magnetism, superconductivity, semiconductor materials and their properties, as well as the use of nuclear techniques in studies of these materials. 162 contributions have been considered to be in the INIS subject scope and were indexed separately.

  5. Lightning and Gunpowder in the 18th Century

    NASA Astrophysics Data System (ADS)

    Krider, E. P.

    2006-12-01

    On or before June, 1751, Benjamin Franklin and co-workers showed that gunpowder could be ignited by a small electric spark, and subsequently people used gunpowder to enhance the explosions of "thunder houses" to demonstrate that grounded metallic rods would protect model structures against lightning damage. Even before the sentry box and kite experiments proved that thunderclouds are electrified and that lightning is an electrical discharge in 1752, Franklin had hypothesized that a tall, well-grounded conductor might reduce or prevent lightning damage by silently discharging the cloud, and if a discharge did occur, then the tall rod would offer a preferred place for the lightning to strike, and the grounding conductors would guide the current into the ground in a harmless fashion. Over the next 10 years, experience gained through practice showed that grounded rods did indeed protect ordinary structures from lightning damage, but a question remained about the best way to protect gunpowder magazines. In 1762, Franklin recommended a tall "mast not far from it, which may reach 15 or 20 feet above the top of it, with a thick iron rod in one piece fastened to it, pointed at the highest end, and reaching down through the earth till it comes to water," and in 1772 he made a similar recommendation for protecting the British powder magazine at Purfleet. In 1780, Jan Ingenhousz asked Franklin to "communicate to me some short hints, which may occur to you about the most convenient manner of constructing gun powder magazines, the manner of preserving the powder from moisture and securing the building in the best manner from the effects of lightning." In his reply, Franklin detailed a method of protection that is almost perfect, "they should be constructed in the Ground; that the Walls should be lin'd with Lead, the Floor Lead, all 1/4 Inch thick & the Joints well solder'd; the Cover Copper; with a little Scuttle to enter, the whole in the Form of a Canister for Tea. If the Edges of the Cover scuttle fall into a Copper Channel containing Mercury, not the smallest Particle of Air or Moisture can enter to the Powder, even tho' the Walls stood in Water, or the whole was under Water." In 1876, the Scottish physicist, James Clerk Maxwell, made almost exactly the same recommendation for protecting against lightning, a method known today as a "Faraday cage."

  6. Using prognostic model-generated meteorological output in the AERMOD dispersion model: an illustrative application in Philadelphia, PA.

    PubMed

    Touma, Jawad S; Isakov, Vlad; Cimorelli, Alan J; Brode, Roger W; Anderson, Bret

    2007-05-01

    In this study, we introduce the prospect of using prognostic model-generated meteorological output as input to steady-state dispersion models by identifying possible advantages and disadvantages and by presenting a comparative analysis. Because output from prognostic meteorological models is now routinely available and is used for Eulerian and Lagrangian air quality modeling applications, we explore the possibility of using such data in lieu of traditional National Weather Service (NWS) data for dispersion models. We apply these data in an urban application where comparisons can be made between the two meteorological input data types. Using the U.S. Environment Protection Agency's American Meteorological Society/U.S. Environmental Protection Agency Regulatory Model (AERMOD) air quality dispersion model, hourly and annual average concentrations of benzene are estimated for the Philadelphia, PA, area using both hourly MM5 model-generated meteorological output and meteorological data taken from the NWS site at the Philadelphia International Airport. Our intent is to stimulate a discussion of the relevant issues and inspire future work that examines many of the questions raised in this paper. PMID:17518224

  7. ED quality performance moves into the public reporting arena.

    PubMed

    2010-09-01

    As an ED manager, you face the growing challenge of your performance data being shared with the public and with hospital administration. Be sure to share the good news with your administration, so they can use it to help market the hospital. When adverse rankings appear, you have two options: Seek additional resources to improve performance, or challenge the data. Use an automated system to access"real-time"data on your department's performance, so you will always be ready to defend your ED. PMID:20853578

  8. Automated SEM-EDS GSR Analysis for Turkish Ammunitions

    SciTech Connect

    Cakir, Ismail; Uner, H. Bulent

    2007-04-23

    In this work, Automated Scanning Electron Microscopy with Energy Dispersive X-ray Spectrometry (SEM-EDS) was used to characterize 7.65 and 9mm cartridges Turkish ammunition. All samples were analyzed in a SEM Jeol JSM-5600LV equipped BSE detector and a Link ISIS 300 (EDS). A working distance of 20mm, an accelerating voltage of 20 keV and gunshot residue software was used in all analysis. Automated search resulted in a high number of particles analyzed containing gunshot residues (GSR) unique elements (PbBaSb). The obtained data about the definition of characteristic GSR particles was concordant with other studies on this topic.

  9. Microbiologic Methods Utilized in the MAL-ED Cohort Study

    PubMed Central

    Houpt, Eric; Gratz, Jean; Kosek, Margaret; Zaidi, Anita K. M.; Qureshi, Shahida; Kang, Gagandeep; Babji, Sudhir; Mason, Carl; Bodhidatta, Ladaporn; Samie, Amidou; Bessong, Pascal; Barrett, Leah; Lima, Aldo; Havt, Alexandre; Haque, Rashidul; Mondal, Dinesh; Taniuchi, Mami; Stroup, Suzanne; McGrath, Monica; Lang, Dennis

    2014-01-01

    A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals. PMID:25305291

  10. Characterization of pyrotechnic reaction residue particles by SEM/EDS.

    PubMed

    Kosanke, Ken L; Dujay, Richard C; Kosanke, Bonnie

    2003-05-01

    Today the method commonly used for detecting gunshot residue is through the combined use of scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). In recent years, this same methodology began to find use in detecting and characterizing pyrotechnic reaction residue (PRR) particles whether produced by explosion or burning. This is accomplished by collecting particulate samples from a surface in the immediate area of the pyrotechnic reaction. Suspect PRR particles are identified by their morphology (typically 1 to 20 microm spheroidal particles) using an SEM; then they are analyzed for the elements they contain using X-ray EDS. This can help to identify the general type of pyrotechnic composition involved. PMID:12762523

  11. Automated SEM-EDS GSR Analysis for Turkish Ammunitions

    NASA Astrophysics Data System (ADS)

    Cakir, Ismail; Uner, H. Bulent

    2007-04-01

    In this work, Automated Scanning Electron Microscopy with Energy Dispersive X-ray Spectrometry (SEM-EDS) was used to characterize 7.65 and 9mm cartridges Turkish ammunition. All samples were analyzed in a SEM Jeol JSM-5600LV equipped BSE detector and a Link ISIS 300 (EDS). A working distance of 20mm, an accelerating voltage of 20 keV and gunshot residue software was used in all analysis. Automated search resulted in a high number of particles analyzed containing gunshot residues (GSR) unique elements (PbBaSb). The obtained data about the definition of characteristic GSR particles was concordant with other studies on this topic.

  12. Mode of Delivery among HIV-Infected Pregnant Women in Philadelphia, 2005-2013

    PubMed Central

    Adams, Joëlla W.; Anderson, Emily A.

    2015-01-01

    Objective Current guidelines call for HIV-infected women to deliver via scheduled Caesarean when the maternal HIV viral load (VL) is >1,000 copies/ml. We describe the mode of delivery among HIV-infected women and evaluate adherence to relevant recommendations. Study Design We performed a population-based surveillance analysis of HIV-infected pregnant women in Philadelphia from 2005 to 2013, comparing mode of delivery (vaginal, scheduled Caesarean, or emergent Caesarean) by VL during pregnancy, closest to the time of delivery (≤1,000 copies/ml versus an unknown VL or VL >1,000 copies/ml) and associated factors in multivariable analysis. Results Our cohort included 824 deliveries from 648 HIV-infected women, of whom 69.4% had a VL ≤1,000 copies/ml and 30.6% lacked a VL or had a VL >1,000 copies/ml during pregnancy, closest to the time of delivery. Mode of delivery varied by VL: 56.6% of births were vaginal, 30.1% scheduled Caesarean, and 13.3% emergent Caesarean when the VL was ≤1,000 copies/ml; when the VL was unknown or >1,000 copies/ml, 32.9% of births were vaginal, 49.9% scheduled Caesarean and 17.5% emergent Caesarean. In multivariable analyses, Hispanic women (adjusted odds ratio (AOR) 0.17, 95% Confidence Interval (CI) 0.04–0.76) and non-Hispanic black women (AOR 0.27, 95% CI 0.10–0.77) were less to likely to deliver via scheduled Caesarean compared to non-Hispanic white women. Women who delivered prior to 38 weeks’ gestation (AOR 0.37, 95% CI 0.18–0.76) were also less likely to deliver via scheduled Caesarean compared to women who delivered after 38 weeks’ gestation. An interaction term for race and gestational age at delivery was significant in multivariable analysis. Non-Hispanic black (AOR 0.06, 95% CI 0.01–0.36) and Hispanic women (AOR 0.03, 95% CI 0.00–0.59) were more likely to deliver prematurely and less likely to deliver via scheduled C-section compared to non-Hispanic white women. Having a previous Caesarean (AOR 27.77, 95% CI 8

  13. Arteriogram

    MedlinePlus

    ... M. Catheterization and angiography. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... Atherosclerotic peripheral arterial disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  14. Food poisoning prevention

    MedlinePlus

    ... with suspected enteric infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  15. Aspiration

    MedlinePlus

    ... diagnosis of benign lesions. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... patient with liver disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  16. Catheter-associated UTI

    MedlinePlus

    ... health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... with urinary tract infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  17. Toxins

    MedlinePlus

    ... trace metals and others. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ... Ford MD. Acute poisoning. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  18. Stent

    MedlinePlus

    ... of coronary artery disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... Atherosclerotic peripheral arterial disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  19. Pulmonary valve stenosis

    MedlinePlus

    ... BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... AJ. Congenital heart disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  20. Alpha-1 antitrypsin deficiency

    MedlinePlus

    ... and metabolic hepatic disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... Chronic obstructive pulmonary disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  1. Hydrocodone and acetaminophen overdose

    MedlinePlus

    ... Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier ... Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier ...

  2. Forehead lift

    MedlinePlus

    ... Nahai F. Managing the cosmetic patient. In: Neligan PC, ed. Plastic Surgery . 3rd ed. Philadelphia, PA: Elsevier ... Mosby; 2014:chap 27. Warren RJ. In: Neligan PC, ed. Plastic Surgery . 3rd ed. Philadelphia, PA: Elsevier ...

  3. Facelift

    MedlinePlus

    ... Nahai F. Managing the cosmetic patient. In: Neligan PC, ed. Plastic Surgery . 3rd ed. Philadelphia, PA: Elsevier ... 2014:chap 27. Warren RJ. Facelift. In: Neligan PC, ed. Plastic Surgery . 3rd ed. Philadelphia, PA: Elsevier ...

  4. Prostate cancer

    MedlinePlus

    ... Wein AJ, Kavoussi LR, Novick AC, Patin AW, Peters CA, eds. Campbell-Walsh Urology . 10th ed. Philadelphia, ... Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, eds. Campbell-Walsh Urology . 10th ed. Philadelphia, ...

  5. Bathroom safety - adults

    MedlinePlus

    ... EH, Katz PR, Malone ML, eds. Practice of Geriatrics . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap ... Warshaw GA, et al., eds. Ham's Primary Care Geriatrics: A Case-Based Approach. . 6th ed. Philadelphia, PA: ...

  6. Aging changes in the kidneys and bladder

    MedlinePlus

    ... EH, Katz PR, Malone ML, eds. Practice of Geriatrics . 4th ed. Philadelphia, PA: Elsevier Mosby; 2007:chap ... EH, Katz PR, Malone ML, eds. Practice of Geriatrics . 4th ed. Philadelphia, PA: Elsevier Mosby; 2007:chap ...

  7. Aging changes in immunity

    MedlinePlus

    ... EH, Katz PR, Malone ML, eds. Practice of Geriatrics . 4th ed. Philadelphia, PA: Elsevier Mosby; 2007:564. ... Rockwood K, Woodhouse K, eds. Brocklehurst's Textbook of Geriatric Medicine and Gerontology. 7th ed. Philadelphia PA: Elsevier ...

  8. Aging changes in the nervous system

    MedlinePlus

    ... EH, Katz PR, Malone ML, eds. Practice of Geriatrics . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap ... EH, Katz PR, Malone ML, eds. Practice of Geriatrics . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap ...

  9. Pulmonary edema

    MedlinePlus

    ... failure: pathophysiology and diagnosis. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... failure: management and prognosis. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  10. Viral gastroenteritis

    MedlinePlus

    ... with suspected enteric infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  11. Basal ganglia dysfunction

    MedlinePlus

    ... 71. Lang AE. Parkinsonism. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... AE. Other movement disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  12. Immune response

    MedlinePlus

    ... inflammation and tissue repair. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... and adaptive immune systems. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  13. Hemoglobin derivatives

    MedlinePlus

    ... Approach to the anemias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... injuries of the lung In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  14. Hypertensive heart disease

    MedlinePlus

    ... failure: pathophysiology and diagnosis. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... Victor RG. Arterial hypertension. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  15. Caplan syndrome

    MedlinePlus

    ... G. Interstitial lung disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... SM. Occupational lung disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  16. Leg pain

    MedlinePlus

    ... J. Peripheral venous disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  17. Campylobacter infection

    MedlinePlus

    ... with suspected enteric infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: ... with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: ...

  18. ALP isoenzyme test

    MedlinePlus

    ... or abnormal liver tests. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ... bladder and bile ducts In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  19. Giardia infection

    MedlinePlus

    ... with suspected enteric infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  20. Salmonella enterocolitis

    MedlinePlus

    ... with suspected enteric infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  1. Catheter-related UTI

    MedlinePlus

    ... health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... with urinary tract infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  2. ALP - blood test

    MedlinePlus

    ... or abnormal liver tests. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ... gallbladder and bile ducts. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  3. Cholera

    MedlinePlus

    ... with suspected enteric infection. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: ...

  4. Staph infections - hospital

    MedlinePlus

    ... health care-associated infections. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... Chambers HF. Staphylococcal infections. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  5. Peritonitis - spontaneous

    MedlinePlus

    ... Cirrhosis and its sequelae. In: Goldman L,Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... peritoneum, mesentery, and omentum. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  6. Aneurysm

    MedlinePlus

    ... of the gastrointestinal tract. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ... Diseases of the aorta. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: ...

  7. Colds and the flu - what to ask your doctor - adult

    MedlinePlus

    ... 2016. Hayden FG. Influenza. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ... RB. The common cold. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  8. Immunofixation -- urine

    MedlinePlus

    ... Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, PA: ... Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ...

  9. Factor IX assay

    MedlinePlus

    ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ...

  10. Factor VIII assay

    MedlinePlus

    ... LE, Heslop HE, Weitz JI, Anastasi, J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ...

  11. Fibrin degradation products

    MedlinePlus

    ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ...

  12. Factor XII assay

    MedlinePlus

    ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ...

  13. Factor X assay

    MedlinePlus

    ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ... LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: ...

  14. Hemolysis

    MedlinePlus

    ... eds. Cecil Medicine . 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 163. Gallagher PG. Hemolytic anemias: red ... eds. Cecil Medicine . 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 164. Gallagher PG, Jarolim P. Red ...

  15. Polycystic kidney disease

    MedlinePlus

    ... eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 129. Porter CC, Avner Ed. ... Nelson Textbook of Pediatrics . 19th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 515. Somlo S, Torres VE, Caplan ...

  16. Small intestine aspirate and culture

    MedlinePlus

    ... eds. Cecil Medicine . 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 291. Semrad CE. Approach to the ... eds. Cecil Medicine . 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 142. Giannella RA. Infectious enteritis and ...

  17. Eye burning - itching and discharge

    MedlinePlus

    ... Duker JS, eds. Ophthalmology . 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 4.7. Rubenstein JB, Tannan ... Duker JS, eds. Ophthalmology . 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 4.6. Snyder RW, Slade ...

  18. Culture - duodenal tissue

    MedlinePlus

    ... eds. Cecil Medicine . 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 291. Semrad CE. Approach to the ... eds. Cecil Medicine . 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 142. Giannella RA. Infectious enteritis and ...

  19. Endoscopy

    MedlinePlus

    ... eds. Campbell-Walsh Urology . 10th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 8. Lentz GM. Endoscopy: hysteroscopy ... VL, eds. Comprehensive Gynecology . 6th ed. Philadelphia, PA: Elsevier Mosby; 2012:chap 10. Phillips BB. General principles ...

  20. Vacuum-assisted delivery

    MedlinePlus

    ... In: Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics: Normal and Problem Pregnancies . 6th ed. Philadelphia, PA: ... EG, Cline MK, Sakornbut EL, eds. Family Medicine Obstetrics . 3rd ed. Philadelphia, PA: Elsevier Mosby; 2008:chap ...